BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1970 (trpB-2) DE:tryptophan synthase, subunit beta (trpB-2)
(451 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75177 tryptophan synthase, chain beta (trpb-2) PAB1970 - P... 916 0.0
sp|O59265|TRPB_PYRHO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437005|... 792 0.0
sp|Q9Y9H2|TRB2_AERPE TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|743700... 633 e-180
gi|11498839 tryptophan synthase, subunit beta (trpB-1) [Archaeog... 552 e-156
sp|O27520|TRB2_METTH TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|743701... 552 e-156
sp|O67409|TRB2_AQUAE TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|743701... 539 e-152
sp|Q9WZ09|TRB2_THEMA TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|743701... 517 e-145
dbj|BAB10143.1| (AB005231) tryptophan synthase beta chain [Arabi... 488 e-137
gb|AAK41171.1| Tryptophan synthase beta chain (trpB) [Sulfolobus... 481 e-135
sp|P50383|TRPB_SULSO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|1004319|... 469 e-131
gb|AAK41396.1| Tryptophan synthase beta chain, hypothetical (trp... 437 e-121
sp|Q9Y8T5|TRB1_AERPE TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|743700... 408 e-113
emb|CAC11807.1| (AL445065) tryptophan synthase, beta chain [Ther... 391 e-108
sp|Q9YGB0|TRPB_PYRKO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|11269298... 174 2e-42
sp|O66923|TRB1_AQUAE TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|743699... 173 4e-42
pir||F75162 tryptophan synthase, chain beta (trpb-1) PAB2048 - P... 173 5e-42
gi|11499193 tryptophan synthase, subunit beta (trpB-2) [Archaeog... 170 3e-41
pir||C81377 tryptophan synthase (EC 4.2.1.20) beta chain Cj0348 ... 165 1e-39
sp|Q60179|TRPB_METJA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|2118310|... 164 2e-39
sp|P14638|TRPB_METVO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|150072|g... 161 1e-38
sp|P19868|TRPB_BACST TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80229|pi... 161 2e-38
prf||1603216A Trp synthase [Bacillus stearothermophilus] 161 2e-38
sp|P56929|TRPB_RHIET TRYPTOPHAN SYNTHASE BETA CHAIN >gi|5834681|... 159 8e-38
sp|O08376|TRPB_MYCTU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7436999|... 157 3e-37
sp|P50909|TRB1_THEMA TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|212037... 155 7e-37
sp|P26921|TRPB_METTM TRYPTOPHAN SYNTHASE BETA CHAIN >gi|99120|pi... 155 1e-36
sp|O27696|TRB1_METTH TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|743700... 155 1e-36
sp|P16609|TRPB_THETH TRYPTOPHAN SYNTHASE BETA CHAIN >gi|94734|pi... 153 4e-36
pir||B81169 tryptophan synthase, beta chain NMB0699 [imported] -... 152 1e-35
pir||H81936 probable tryptophan synthase (EC 4.2.1.20) beta chai... 152 1e-35
gb|AAF61457.1|AF139661_2 (AF139661) tryptophan synthase beta sub... 151 1e-35
pir||D75455 tryptophan synthase, beta subunit - Deinococcus radi... 151 1e-35
sp|Q01998|TRPB_LACLA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|421430|p... 150 2e-35
sp|O68905|TRPB_MYCIT TRYPTOPHAN SYNTHASE BETA CHAIN >gi|3152733|... 150 2e-35
sp|P12290|TRPB_CAUCR TRYPTOPHAN SYNTHASE BETA CHAIN >gi|279952|p... 150 3e-35
dbj|BAB05382.1| (AP001512) tryptophan synthase (beta subunit) [B... 148 9e-35
sp|P16706|TRPB_ACICA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|95335|pi... 147 2e-34
pir||T07937 tryptophan synthase (EC 4.2.1.20) beta chain - Chlam... 147 3e-34
sp|Q59169|TRPB_BUCSC TRYPTOPHAN SYNTHASE BETA CHAIN >gi|769838|g... 146 3e-34
sp|P14671|TRP1_ARATH TRYPTOPHAN SYNTHASE BETA CHAIN 1 PRECURSOR ... 145 1e-33
gb|AAD51338.1|AF173835_2 (AF173835) tryptophan synthetase beta s... 144 2e-33
sp|P00933|TRPB_SALTY TRYPTOPHAN SYNTHASE BETA CHAIN >gi|4699724|... 143 3e-33
pir||TSEBBT tryptophan synthase (EC 4.2.1.20) beta chain - Salmo... 143 3e-33
sp|P13228|TRP_NEUCR TRYPTOPHAN SYNTHASE >gi|101877|pir||A32959 t... 143 3e-33
sp|P25269|TRP2_ARATH TRYPTOPHAN SYNTHASE BETA CHAIN 2 PRECURSOR ... 143 3e-33
pdb|1QOP|B Chain B, Crystal Structure Of Wild-Type Tryptophan Sy... 143 3e-33
pir||JN0593 tryptophan synthase (EC 4.2.1.20) beta chain - Bacil... 143 4e-33
sp|O05625|TRPB_STRCO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7481832|... 143 4e-33
pdb|1BEU|B Chain B, Trp Synthase (D60n-Ipp-Ser) With K+ >gi|3212... 143 4e-33
pdb|1QOQ|B Chain B, Crystal Structure Of Wild-Type Tryptophan Sy... 143 4e-33
gb|AAC60450.1| (S65045) tryptophan synthase beta-subunit, TrpB [... 143 5e-33
gb|AAF91181.1|AF207903_2 (AF207903) bifunctional tryptophan synt... 142 7e-33
sp|Q9ZJU9|TRPB_HELPJ TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437012|... 142 9e-33
sp|P56142|TRPB_HELPY TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437003|... 141 1e-32
pir||T47190 tryptophan synthase (EC 4.2.1.20) beta chain [import... 141 2e-32
pdb|2TYS|B Chain B, Crystal Structures Of Mutant (Betak87t) Tryp... 141 2e-32
pir||H83640 tryptophan synthase beta chain PA0036 [imported] - P... 141 2e-32
sp|P00932|TRPB_ECOLI TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7428396|... 141 2e-32
gb|AAA65145.1| (U23491) tryptophan synthase beta subunit [Escher... 141 2e-32
gb|AAB60040.1| (U23495) tryptophan synthase beta subunit [Escher... 141 2e-32
pdb|1UBS|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) With A Mu... 141 2e-32
dbj|BAA14793.1| (D90763) Tryptophan synthase b chain (EC 4.2.1.2... 141 2e-32
pir||E82232 tryptophan synthase, beta chain VC1170 [imported] - ... 141 2e-32
gb|AAA73808.1| (U25420) tryptophan synthase beta subunit [Escher... 140 3e-32
pir||TSPSBA tryptophan synthase (EC 4.2.1.20) beta chain - Pseud... 140 3e-32
sp|P07345|TRPB_PSEAE TRYPTOPHAN SYNTHASE BETA CHAIN >gi|151616|g... 140 3e-32
sp|P34817|TRPB_PSESY TRYPTOPHAN SYNTHASE BETA CHAIN >gi|476480|p... 140 3e-32
pir||JQ1073 tryptophan synthase (EC 4.2.1.20) beta-2 chain precu... 140 3e-32
sp|P07600|TRPB_BACSU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80435|pi... 139 5e-32
sp|P17167|TRPB_LACCA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80566|pi... 139 6e-32
sp|P43284|TRP2_MAIZE TRYPTOPHAN SYNTHASE BETA CHAIN 2 PRECURSOR ... 139 6e-32
gb|AAA65169.1| (U23496) tryptophan synthase beta subunit [Escher... 139 6e-32
gb|AAA73814.1| (U25421) tryptophan synthase beta subunit [Escher... 139 6e-32
gb|AAA73832.1| (U25425) tryptophan synthase beta subunit [Escher... 139 6e-32
gi|6321412 tryptophan synthetase; Trp5p [Saccharomyces cerevisia... 139 8e-32
sp|P16578|TRP_COPCI TRYPTOPHAN SYNTHASE >gi|83890|pir||JU0401 tr... 138 1e-31
sp|P22097|TRPB_VIBPA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|48490|em... 138 1e-31
sp|P43283|TRP1_MAIZE TRYPTOPHAN SYNTHASE BETA CHAIN 1 (ORANGE PE... 138 2e-31
sp|P42391|TRPB_BUCAP TRYPTOPHAN SYNTHASE BETA CHAIN >gi|625652|p... 138 2e-31
sp|Q44687|TRPB_BUCMH TRYPTOPHAN SYNTHASE BETA CHAIN >gi|6492283|... 138 2e-31
sp|O50046|TRPB_CAMAC TRYPTOPHAN SYNTHASE BETA CHAIN 2 PRECURSOR ... 137 2e-31
sp|O13831|TRP_SCHPO TRYPTOPHAN SYNTHASE >gi|7493535|pir||T37946 ... 137 3e-31
pir||C82688 tryptophan synthase beta chain XF1375 [imported] - X... 137 3e-31
sp|O68428|TRPB_BUCDN TRYPTOPHAN SYNTHASE BETA CHAIN >gi|3170097|... 136 4e-31
sp|Q9X4E5|TRPB_RHOSH TRYPTOPHAN SYNTHASE BETA CHAIN >gi|4761127|... 135 9e-31
sp|P11080|TRPB_PSEPU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|77778|pi... 134 3e-30
sp|O84172|TRPB_CHLTR TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437000|... 133 3e-30
pir||T04330 probable tryptophan synthase (EC 4.2.1.20) beta chai... 132 6e-30
sp|P43760|TRPB_HAEIN TRYPTOPHAN SYNTHASE BETA CHAIN >gi|1075400|... 131 1e-29
sp|Q59992|TRPB_SYNY3 TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437004|... 131 2e-29
sp|P06561|TRPB_BRELA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80602|pi... 126 4e-28
sp|P18285|TRPB_HALVO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|99231|pi... 125 8e-28
sp|Q44685|TRPB_BUCAI TRYPTOPHAN SYNTHASE BETA CHAIN >gi|10038953... 125 8e-28
sp|P54203|TRPB_PASMU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|733125|g... 123 5e-27
pir||T45257 probable tryptophan synthase (EC 4.2.1.20) beta chai... 122 9e-27
emb|CAA79516.1| (Z19090) tryptophan synthase; beta subunit [Vibr... 120 3e-26
gb|AAG18887.1| (AE004991) tryptophan synthase beta chain; TrpB [... 117 2e-25
dbj|BAA14796.1| (D90764) Tryptophan synthase b chain (EC 4.2.1.2... 115 1e-24
pir||T42090 tryptophan synthase (EC 4.2.1.20) - fission yeast (... 114 2e-24
emb|CAB42885.2| (AJ239040) tryptophan synthase beta-subunit [Pre... 109 8e-23
gb|AAD17312.1| (AF121272) putative tryptophan synthase beta subu... 99 9e-20
gb|AAG14886.1|AF293320_2 (AF293320) tryptophan synthase beta sub... 89 1e-16
gb|AAG14782.1|AF293268_2 (AF293268) tryptophan synthase beta sub... 87 3e-16
gb|AAG14874.1|AF293314_2 (AF293314) tryptophan synthase beta sub... 87 3e-16
gb|AAG14864.1|AF293309_2 (AF293309) tryptophan synthase beta sub... 87 4e-16
gb|AAG14784.1|AF293269_2 (AF293269) tryptophan synthase beta sub... 86 9e-16
gb|AAG14800.1|AF293277_2 (AF293277) tryptophan synthase beta sub... 85 2e-15
gb|AAD04365.1| (AF084897) mutant tryptophan synthase [Neurospora... 71 3e-11
>pir||F75177 tryptophan synthase, chain beta (trpb-2) PAB1970 - Pyrococcus
abyssi (strain Orsay) >gi|5458011|emb|CAB49501.1|
(AJ248284) tryptophan synthase, subunit beta (trpB-2)
[Pyrococcus abyssi]
Length = 451
Score = 916 bits (2342), Expect = 0.0
Identities = 451/451 (100%), Positives = 451/451 (100%)
Query: 1 MLFYQCREVPSMKVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEE 60
MLFYQCREVPSMKVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEE
Sbjct: 1 MLFYQCREVPSMKVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEE 60
Query: 61 LVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSH 120
LVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSH
Sbjct: 61 LVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSH 120
Query: 121 KINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRK 180
KINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRK
Sbjct: 121 KINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRK 180
Query: 181 TLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVL 240
TLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVL
Sbjct: 181 TLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVL 240
Query: 241 NHVLMHQTVIGLEAKEQMEEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAV 300
NHVLMHQTVIGLEAKEQMEEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAV
Sbjct: 241 NHVLMHQTVIGLEAKEQMEEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAV 300
Query: 301 EPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLIN 360
EPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLIN
Sbjct: 301 EPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLIN 360
Query: 361 HGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNL 420
HGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNL
Sbjct: 361 HGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNL 420
Query: 421 SGHGLLDLKGYEDYLDGKLEDYEPRDLPVKS 451
SGHGLLDLKGYEDYLDGKLEDYEPRDLPVKS
Sbjct: 421 SGHGLLDLKGYEDYLDGKLEDYEPRDLPVKS 451
>sp|O59265|TRPB_PYRHO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437005|pir||G71036 probable
tryptophan synthase beta chain - Pyrococcus horikoshii
>gi|3258012|dbj|BAA30695.1| (AP000006) 459aa long
hypothetical tryptophan synthase beta chain [Pyrococcus
horikoshii]
Length = 459
Score = 792 bits (2022), Expect = 0.0
Identities = 381/435 (87%), Positives = 414/435 (94%)
Query: 13 KVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYI 72
K +L DG IP+RWYNILPDLPEPL PPLDPET E I+ EKL RIFA+EL+KQE S +RYI
Sbjct: 13 KSILKDGEIPKRWYNILPDLPEPLSPPLDPETNETINPEKLTRIFAKELIKQEFSEKRYI 72
Query: 73 EIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYA 132
+IP E+R+LY+KIGRPTPLFRATNLEK+L TPARIYFKYEGATVTGSHKINTALAQAYYA
Sbjct: 73 KIPKEVRELYAKIGRPTPLFRATNLEKILKTPARIYFKYEGATVTGSHKINTALAQAYYA 132
Query: 133 KKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFP 192
KK+GI+RLVTETGAGQWGTALSLAGAL+GLKVRVYM RASY QKPYRK LM IYGAEVFP
Sbjct: 133 KKEGIKRLVTETGAGQWGTALSLAGALIGLKVRVYMTRASYYQKPYRKILMEIYGAEVFP 192
Query: 193 SPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGL 252
SPSENTEVGKRFL+EDPNHPGSLGIAISEAIEDVL DEKARYSLGSVLNHVLMHQTVIGL
Sbjct: 193 SPSENTEVGKRFLREDPNHPGSLGIAISEAIEDVLSDEKARYSLGSVLNHVLMHQTVIGL 252
Query: 253 EAKEQMEEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGV 312
EAK+Q++EFEEPDVIIGCVGGGSNFAGL+YPF+KDVLDGK+EYEFIAVEP+A PTMT+GV
Sbjct: 253 EAKKQVKEFEEPDVIIGCVGGGSNFAGLSYPFIKDVLDGKAEYEFIAVEPRAVPTMTKGV 312
Query: 313 YTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQT 372
YTYDYGDSAGLTPK+KM+TLGH YYVPPIHAGGLRYHGLAPTLSVL+NHGIVKP+AYHQT
Sbjct: 313 YTYDYGDSAGLTPKIKMYTLGHTYYVPPIHAGGLRYHGLAPTLSVLMNHGIVKPMAYHQT 372
Query: 373 EVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYE 432
EVFEAAVLFAKAEGIVPAPESAHAV+AVIDKALEA+R+G+E VILFNLSGHGLLDLKGYE
Sbjct: 373 EVFEAAVLFAKAEGIVPAPESAHAVRAVIDKALEAKRKGEETVILFNLSGHGLLDLKGYE 432
Query: 433 DYLDGKLEDYEPRDL 447
DYL+GKLEDYEP+ L
Sbjct: 433 DYLEGKLEDYEPQIL 447
>sp|Q9Y9H2|TRB2_AERPE TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|7437006|pir||H72458 probable
tryptophan synthase beta chain APE2316 - Aeropyrum
pernix (strain K1) >gi|5106017|dbj|BAA81328.1|
(AP000064) 449aa long hypothetical tryptophan synthase
beta chain [Aeropyrum pernix]
Length = 449
Score = 633 bits (1614), Expect = e-180
Identities = 305/431 (70%), Positives = 356/431 (81%), Gaps = 3/431 (0%)
Query: 21 IPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRK 80
+P WYNILPDLPE + PPL+P+T EP+D L ++F + L++QE+SRERYIEIPGE+ +
Sbjct: 15 VPTSWYNILPDLPEEVPPPLNPKTGEPVDPSALAKLFPKALIEQEVSRERYIEIPGEVHE 74
Query: 81 LYSKIGR-PTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIER 139
Y R PTPL RA NLE+ L TPA IY+KYEG T TGSHKINTALAQAYY K +G+ER
Sbjct: 75 AYISFARRPTPLLRAVNLERALNTPAEIYYKYEGVTPTGSHKINTALAQAYYNKLEGVER 134
Query: 140 LVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTE 199
LVTETGAGQWG+ALS AGA G+KVRVYM R SY QKPYR+TLM +YGAEV+PSPS+ TE
Sbjct: 135 LVTETGAGQWGSALSAAGAYFGVKVRVYMVRVSYLQKPYRRTLMELYGAEVYPSPSDKTE 194
Query: 200 VGKRFLKEDPNHPGSLGIAISEAIEDVLKDE-KARYSLGSVLNHVLMHQTVIGLEAKEQM 258
G++ L E+PNHPGSLGIAISEAIEDV+ A+YSLGSVLNHVL+HQTVIGLEA++Q
Sbjct: 195 FGRKLLAENPNHPGSLGIAISEAIEDVINSGGNAKYSLGSVLNHVLLHQTVIGLEAEKQF 254
Query: 259 EEFEE-PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDY 317
E PD++IG VGGGSNFAG YPF++ L G S FIAVEPKA+P+MTRGVYTYDY
Sbjct: 255 REAGVYPDIMIGAVGGGSNFAGFTYPFIRHRLKGSSSTRFIAVEPKASPSMTRGVYTYDY 314
Query: 318 GDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEA 377
GD+AGLTP LKMHTLGH Y VPPIHAGGLRYHG+APTLSVL+ HGIV+ AYHQ EVF A
Sbjct: 315 GDTAGLTPLLKMHTLGHTYQVPPIHAGGLRYHGVAPTLSVLLKHGIVEARAYHQREVFRA 374
Query: 378 AVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLDG 437
A +FAKAEGIVPAPESAHAVKA ID+A++AR EG+ +VI FNLSGHGLLDL+GY +YLDG
Sbjct: 375 AHMFAKAEGIVPAPESAHAVKAAIDEAIKARDEGRRVVIAFNLSGHGLLDLQGYREYLDG 434
Query: 438 KLEDYEPRDLP 448
LEDYEP ++P
Sbjct: 435 TLEDYEPEEIP 445
>gi|11498839 tryptophan synthase, subunit beta (trpB-1) [Archaeoglobus fulgidus]
>gi|7674372|sp|O29028|TRB2_ARCFU TRYPTOPHAN SYNTHASE
BETA CHAIN 2 >gi|7437017|pir||G69404 tryptophan
synthase, subunit beta (trpB-1) homolog - Archaeoglobus
fulgidus >gi|2649345|gb|AAB90007.1| (AE001019)
tryptophan synthase, subunit beta (trpB-1)
[Archaeoglobus fulgidus]
Length = 435
Score = 552 bits (1408), Expect = e-156
Identities = 266/430 (61%), Positives = 331/430 (76%), Gaps = 4/430 (0%)
Query: 13 KVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYI 72
K++L + +P+ WYN+LPDLPEPL PPL P T+EP+ E L+ IF + L++QE+S ER+I
Sbjct: 8 KIMLDESEMPKEWYNVLPDLPEPLPPPLHPATQEPVKPEDLEPIFPKGLIQQEMSGERWI 67
Query: 73 EIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYA 132
IP ++R++Y +I RPTPL RA LEK L TPARIYFKYEGA+ GSHK NTA+AQAYY
Sbjct: 68 RIPEDVREIY-RIWRPTPLVRAERLEKALKTPARIYFKYEGASPPGSHKPNTAVAQAYYN 126
Query: 133 KKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFP 192
K+G+ERL TETGAGQWG+AL A L + VYM + S+ QKPYR+ +M +G EV P
Sbjct: 127 AKEGVERLTTETGAGQWGSALCFATKLFEMACTVYMVKVSFMQKPYRRVMMETWGGEVIP 186
Query: 193 SPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGL 252
SPS+ TEVG++ L E+P+ PGSLGIAISEAIED K+E +YSLGSVLNHVL+HQTVIGL
Sbjct: 187 SPSDRTEVGRKILAENPDTPGSLGIAISEAIEDAAKNENTKYSLGSVLNHVLLHQTVIGL 246
Query: 253 EAKEQMEEFEE-PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRG 311
E K Q+E+ +E PDV+IGCVGGGSNFAGL YPFV D +G + E IAVEP A PT+T G
Sbjct: 247 ETKAQLEKVDEKPDVLIGCVGGGSNFAGLTYPFVNDAKNG--DLEIIAVEPAACPTLTAG 304
Query: 312 VYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQ 371
Y YD+GD AGLTP LKM+TLGH + PPIHAGGLRYHG APTL +L+ HG++K A Q
Sbjct: 305 EYKYDFGDVAGLTPLLKMYTLGHDFIPPPIHAGGLRYHGDAPTLCMLVKHGVIKARAVKQ 364
Query: 372 TEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGY 431
FEA +LFA+ EGI+PAPE+ HAV+A ID+A++AR +E VI+F SGHGLLDL+ Y
Sbjct: 365 LPTFEAGLLFARTEGIIPAPETNHAVRAAIDEAIKARENNEEKVIVFGFSGHGLLDLQAY 424
Query: 432 EDYLDGKLED 441
+DYL G+L D
Sbjct: 425 DDYLAGRLAD 434
>sp|O27520|TRB2_METTH TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|7437016|pir||F69063 tryptophan
synthase, beta subunit homolog - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622591|gb|AAB85951.1| (AE000908) tryptophan
synthase, beta subunit homolog [Methanobacterium
thermoautotrophicum]
Length = 429
Score = 552 bits (1407), Expect = e-156
Identities = 260/428 (60%), Positives = 334/428 (77%), Gaps = 3/428 (0%)
Query: 13 KVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYI 72
K+VL + IP++WYNI PDLP PL P +PE + +IE L R+F+ +++QE+S ER+I
Sbjct: 4 KIVLDENEIPKKWYNINPDLPSPLPEPKNPEGGK--NIENLPRVFSRGVLEQEMSMERWI 61
Query: 73 EIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYA 132
+IP E+ +Y IGRPTPLFRA LE++L TPARIY+K E + TGSHK+NTA+AQAYYA
Sbjct: 62 KIPREVMDVYKMIGRPTPLFRAKGLEEMLDTPARIYYKREDYSPTGSHKLNTAIAQAYYA 121
Query: 133 KKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFP 192
+K G ERL TETGAGQWGTALSLA +L+ L+ +VYM R S+ QKP+RKT+M++YG EV P
Sbjct: 122 RKDGAERLTTETGAGQWGTALSLACSLMDLQCKVYMVRVSFNQKPFRKTIMQLYGGEVVP 181
Query: 193 SPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGL 252
SPS +TE G+R LKEDP HPGSLGIAISEA+E+ L++E YSLGSVLNHVL+HQTVIGL
Sbjct: 182 SPSNHTEFGRRMLKEDPEHPGSLGIAISEAMEEALQEENVYYSLGSVLNHVLLHQTVIGL 241
Query: 253 EAKEQME-EFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRG 311
E K+Q+E E PD++IGCVGGGSNF G +PFVKD LDGK + EFIA EPK+ PT+T G
Sbjct: 242 ETKKQLEIAGETPDIMIGCVGGGSNFGGAIFPFVKDKLDGKLDCEFIAAEPKSCPTLTAG 301
Query: 312 VYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQ 371
Y YD+GD+AG+TP LKM+TLGH + P +HAGGLRYHG++P +++L+ G++ A Q
Sbjct: 302 EYRYDFGDTAGMTPLLKMYTLGHDFVPPSVHAGGLRYHGMSPQVALLVREGVINARAVPQ 361
Query: 372 TEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGY 431
+FE+ V FAKAEG+VPAPE+ HA+ ID+A + R G+E I+ + SGHGLLDLKGY
Sbjct: 362 HTIFESGVKFAKAEGVVPAPETCHAISVAIDEARKCRETGEEKTIVISFSGHGLLDLKGY 421
Query: 432 EDYLDGKL 439
DYL+GK+
Sbjct: 422 GDYLEGKI 429
>sp|O67409|TRB2_AQUAE TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|7437010|pir||G70422 tryptophan
synthase beta subunit - Aquifex aeolicus
>gi|2983814|gb|AAC07370.1| (AE000739) tryptophan
synthase beta subunit [Aquifex aeolicus]
Length = 434
Score = 539 bits (1374), Expect = e-152
Identities = 268/433 (61%), Positives = 327/433 (74%), Gaps = 5/433 (1%)
Query: 13 KVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYI 72
K +L +G IP++W NILP LPEPL+PPLDPET EP+ EKL IF E LV+QE+S + +I
Sbjct: 3 KFLLSEGEIPKKWLNILPLLPEPLEPPLDPETMEPVKPEKLLAIFPEPLVEQEVSDKEWI 62
Query: 73 EIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYA 132
+IP E+ +YS + RPTPL RA NLE+ LGTPA+I++K E + GSHK NTA+AQAYY
Sbjct: 63 DIPEEVLDIYS-LWRPTPLHRAKNLEEFLGTPAKIFYKNESVSPPGSHKPNTAVAQAYYN 121
Query: 133 KKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFP 192
K G++RL TETGAGQWG+ALS A L+ RVYM R SY QKPYR+ LM + EV P
Sbjct: 122 KISGVKRLTTETGAGQWGSALSFATQFFDLQCRVYMVRVSYNQKPYRRILMETWKGEVIP 181
Query: 193 SPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGL 252
SPS T G+++ +E+P HPGSLGIAISEAIE+ E +YSLGSVLNHVL+HQTVIGL
Sbjct: 182 SPSPYTNAGRKYYEENPEHPGSLGIAISEAIEEAASREDTKYSLGSVLNHVLLHQTVIGL 241
Query: 253 EAKEQMEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDG---KSEYEFIAVEPKAAPTM 308
EAK+QMEE PDVIIG VGGGSNFAGL++PF+ DVL G K + + +AVEP+A PT+
Sbjct: 242 EAKKQMEEAGYYPDVIIGAVGGGSNFAGLSFPFLADVLRGDKRKEDLKVLAVEPEACPTL 301
Query: 309 TRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIA 368
T+G Y YD+GDS GLTP +KM+TLGH + PIHAGGLRYHG AP + L N G + +A
Sbjct: 302 TKGEYKYDFGDSVGLTPLIKMYTLGHDFVPSPIHAGGLRYHGDAPLVCKLYNLGYIDAVA 361
Query: 369 YHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
Y QTEVFEAAV FA+ EGIVPAPESAHA+KA ID+AL+ + G+E VILFNLSGHG DL
Sbjct: 362 YKQTEVFEAAVTFARTEGIVPAPESAHAIKAAIDEALKCKETGEEKVILFNLSGHGYFDL 421
Query: 429 KGYEDYLDGKLED 441
Y+ YL G+L D
Sbjct: 422 SAYDKYLHGELTD 434
>sp|Q9WZ09|TRB2_THEMA TRYPTOPHAN SYNTHASE BETA CHAIN 2 >gi|7437015|pir||H72363 tryptophan
synthase, beta subunit - Thermotoga maritima (strain
MSB8) >gi|4981053|gb|AAD35624.1|AE001729_4 (AE001729)
tryptophan synthase, beta subunit [Thermotoga maritima]
Length = 422
Score = 517 bits (1316), Expect = e-145
Identities = 254/419 (60%), Positives = 318/419 (75%), Gaps = 3/419 (0%)
Query: 14 VVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIE 73
V L IP+ WYN+L DLP LDPPLDPET++PI EKL IF L++QE+S ER+IE
Sbjct: 5 VNLKPEEIPKHWYNVLADLPFKLDPPLDPETKQPISPEKLSVIFPMSLIEQEVSEERFIE 64
Query: 74 IPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAK 133
IP + K Y+ + RPTPL RAT LE+ L TPARIY+KYEG + TGSHK NTA+AQAYY K
Sbjct: 65 IPEPVLKEYA-VYRPTPLIRATFLEEYLQTPARIYYKYEGVSPTGSHKPNTAIAQAYYNK 123
Query: 134 KQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPS 193
+G++RLVTETGAGQWG+ALS AGA GL+V+V+M + SYQQKP RK +M ++G +V PS
Sbjct: 124 IEGVKRLVTETGAGQWGSALSYAGAKFGLEVKVFMVKVSYQQKPMRKYMMNLFGGKVTPS 183
Query: 194 PSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGLE 253
PSE T G++ L EDP++PGSLGIAISEA+E + D +YSLGSVLNHVL+HQTVIGLE
Sbjct: 184 PSEETNFGRKILSEDPDNPGSLGIAISEALEVAVSDPNTKYSLGSVLNHVLLHQTVIGLE 243
Query: 254 AKEQMEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGV 312
K+Q+E E+PD+++GC GGGSNF G PFV D L G+ + F+A EP A P++T+G
Sbjct: 244 IKKQLELIGEKPDILLGCHGGGSNFGGTILPFVPDKLSGR-DIRFVACEPAACPSLTKGN 302
Query: 313 YTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQT 372
Y YD+GD+AGLTP LKM+TLG + P IHAGGLRYHG AP ++ L+ G+V+ A+ Q
Sbjct: 303 YDYDFGDTAGLTPLLKMYTLGKDFIPPKIHAGGLRYHGSAPIIARLVKEGLVEAQAFDQD 362
Query: 373 EVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGY 431
E FEAA +FAK EGI+PAPESAHA+ I +A +A+ EGKE VI+F LSGHGLLDL Y
Sbjct: 363 ETFEAAKIFAKLEGIIPAPESAHAIAGAIREAKKAKEEGKERVIVFTLSGHGLLDLTAY 421
>dbj|BAB10143.1| (AB005231) tryptophan synthase beta chain [Arabidopsis thaliana]
Length = 506
Score = 488 bits (1242), Expect = e-137
Identities = 234/422 (55%), Positives = 306/422 (72%), Gaps = 2/422 (0%)
Query: 21 IPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRK 80
IP++WYN++ DL PPL P+T EPI E L +F EL+KQE ++ER+I+IP E+ +
Sbjct: 67 IPKQWYNLVADLSVKPPPPLHPKTFEPIKPEDLAHLFPNELIKQEATQERFIDIPEEVLE 126
Query: 81 LYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+Y K+ RPTPL RA LEKLL TPARIYFKYEG + GSHK NTA+ QAYY K+G++ +
Sbjct: 127 IY-KLWRPTPLIRAKRLEKLLQTPARIYFKYEGGSPAGSHKPNTAVPQAYYNAKEGVKNV 185
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
VTETGAGQWG++L+ A +L GL V+ SY KPYR+ +M+ +GA+V PSPS+ TE
Sbjct: 186 VTETGAGQWGSSLAFASSLFGLDCEVWQVANSYHTKPYRRLMMQTWGAKVHPSPSDLTEA 245
Query: 201 GKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGLEAKEQMEE 260
G+R L+ DP+ PGSLGIAISEA+E ++E +Y LGSVLNHVL+HQT+IG E +QME
Sbjct: 246 GRRILESDPSSPGSLGIAISEAVEVAARNEDTKYCLGSVLNHVLLHQTIIGEECIQQMEN 305
Query: 261 F-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDYGD 319
F E PD+IIGC GGGSNFAGL++PF+++ L GK AVEP A P++T+GVY YD+GD
Sbjct: 306 FGETPDLIIGCTGGGSNFAGLSFPFIREKLKGKINPVIRAVEPSACPSLTKGVYAYDFGD 365
Query: 320 SAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAV 379
+AGLTP +KMHTLGH + PIHAGGLRYHG+AP +S + G ++ I+ Q E F+ A+
Sbjct: 366 TAGLTPLMKMHTLGHDFIPDPIHAGGLRYHGMAPLISHVYEQGFMEAISIPQIECFQGAI 425
Query: 380 LFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLDGKL 439
FA+ EGI+PAPE HA+ A I +AL + G+ VIL + GHG DL Y+ YL G+L
Sbjct: 426 QFARTEGIIPAPEPTHAIAATIREALRCKETGEAKVILMAMCGHGHFDLTSYDKYLKGEL 485
Query: 440 ED 441
D
Sbjct: 486 VD 487
>gb|AAK41171.1| Tryptophan synthase beta chain (trpB) [Sulfolobus solfataricus]
Length = 425
Score = 481 bits (1225), Expect = e-135
Identities = 236/423 (55%), Positives = 314/423 (73%), Gaps = 6/423 (1%)
Query: 14 VVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIE 73
+V D +P+ WYNI+PDLP+PL PP DP+ I+ L+ I +E+++Q+ + ERYI+
Sbjct: 1 MVKEDEILPKYWYNIIPDLPKPLPPPRDPQGAYFSRIDLLRSILPKEVLRQQFTIERYIK 60
Query: 74 IPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAK 133
IP E+R Y IGRPTPLFRA LE+ L TPARIYFKYEGAT TGSHKINTA+ QAY+AK
Sbjct: 61 IPEEVRDRYLSIGRPTPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTAIPQAYFAK 120
Query: 134 KQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPS 193
++GIE +VTETGAGQWGTA++LA ++ +K ++M + SY+QKP R+++M++YGA V+ S
Sbjct: 121 EEGIEHVVTETGAGQWGTAVALAASMYNMKSTIFMVKVSYEQKPMRRSIMQLYGANVYAS 180
Query: 194 PSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGLE 253
P+ TE G++ L+ +P HPGSLGIA+SEAIE LK+E RY +GSVL+ VL+HQ+VIG E
Sbjct: 181 PTNLTEYGRKILETNPQHPGSLGIAMSEAIEYALKNE-FRYLVGSVLDVVLLHQSVIGQE 239
Query: 254 AKEQMEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGV 312
Q++ E+ D++IGCVGGGSNF G YPF+ K +IAV P ++G
Sbjct: 240 TITQLDLLGEDADILIGCVGGGSNFGGFTYPFI----GNKKGKRYIAVSSAEIPKFSKGE 295
Query: 313 YTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQT 372
Y YD+ DSAGL P +KM TLG Y PPI+AGGLRYHG+APTLS+L GIV+ Y++
Sbjct: 296 YKYDFPDSAGLLPLVKMITLGKDYVPPPIYAGGLRYHGVAPTLSLLTKEGIVEWREYNER 355
Query: 373 EVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYE 432
E+FEAA +F + +GIVPAPESAHA++AV+D+A+EAR+ + VI+FNLSGHGLLDL YE
Sbjct: 356 EIFEAAKIFIENQGIVPAPESAHAIRAVVDEAIEARKNNERKVIVFNLSGHGLLDLSNYE 415
Query: 433 DYL 435
+
Sbjct: 416 SMM 418
>sp|P50383|TRPB_SULSO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|1004319|emb|CAA90307.1| (Z50014)
tryptophan synthase component b [Sulfolobus
solfataricus]
Length = 425
Score = 469 bits (1194), Expect = e-131
Identities = 232/423 (54%), Positives = 309/423 (72%), Gaps = 6/423 (1%)
Query: 14 VVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIE 73
+V D +P+ WYNI+PDLP+PL PP DP+ I+ L+ I +E+++Q+ + ERYI+
Sbjct: 1 MVKEDEILPKYWYNIIPDLPKPLPPPRDPQGAYFSRIDLLRSILPKEVLRQQFTIERYIK 60
Query: 74 IPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAK 133
IP E+R Y IGRPTPLFRA LE+ L TPARIYFKYEGAT TGSHKINTA+ QAY+AK
Sbjct: 61 IPEEVRDRYLSIGRPTPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTAIPQAYFAK 120
Query: 134 KQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPS 193
++GIE VTETG GQ G A++L ++ +K ++ + SY+QKP R+++M++YGA V+ S
Sbjct: 121 EEGIEHAVTETGXGQRGNAVALXASMYNMKSTIFTVKVSYEQKPMRRSIMQLYGANVYAS 180
Query: 194 PSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGLE 253
P+ TE G++ L+ +P HPGSLGIA+SEAIE LK+E RY +GSVL+ VL+HQ+VIG E
Sbjct: 181 PTNLTEYGRKILETNPQHPGSLGIAMSEAIEYALKNE-FRYLVGSVLDVVLLHQSVIGQE 239
Query: 254 AKEQMEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGV 312
Q++ E+ D++IGCVGGGSNFAG YPF+ K +IAV P ++G
Sbjct: 240 TITQLDLLGEDADILIGCVGGGSNFAGFTYPFI----GNKKGKRYIAVSSAEIPKFSKGE 295
Query: 313 YTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQT 372
Y YD+ DSAGL P +KM TLG Y PPI+AGGLRYHG+APTLS+L GIV+ Y++
Sbjct: 296 YKYDFPDSAGLLPLVKMITLGKDYVPPPIYAGGLRYHGVAPTLSLLTKEGIVEWREYNER 355
Query: 373 EVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYE 432
E+FEAA +F + +GIVPAPESAHA++AV+D+A+EAR+ + VI+FNLSGHGLLDL YE
Sbjct: 356 EIFEAAKIFIENQGIVPAPESAHAIRAVVDEAIEARKNNERKVIVFNLSGHGLLDLSNYE 415
Query: 433 DYL 435
+
Sbjct: 416 SMM 418
>gb|AAK41396.1| Tryptophan synthase beta chain, hypothetical (trpB-like)
[Sulfolobus solfataricus]
Length = 429
Score = 437 bits (1111), Expect = e-121
Identities = 218/426 (51%), Positives = 298/426 (69%), Gaps = 6/426 (1%)
Query: 12 MKVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERY 71
+++ LP IP +WYNILPDLPE L PP DP + +E LK + ++++ E ++ERY
Sbjct: 5 IRIDLPQDEIPAQWYNILPDLPEELPPPQDPTGKS---LELLKEVLPSKVLELEFAKERY 61
Query: 72 IEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYY 131
++IP E+ + Y ++GRPTP+ RA LE+ LG +IY K E T TGSHKIN+ALA YY
Sbjct: 62 VKIPDEVLERYLQVGRPTPIIRAKRLEEYLGNNIKIYLKMESYTYTGSHKINSALAHVYY 121
Query: 132 AKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVF 191
AK + + TETGAGQWG++++LA AL +K ++M R SY KPYRK +M++YGAEV
Sbjct: 122 AKLDNAKFVTTETGAGQWGSSVALASALFRMKAHIFMVRTSYYAKPYRKYMMQMYGAEVH 181
Query: 192 PSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIG 251
PSPS+ TE G++ L +D NHPGSLGIAIS+A+E K+ +Y +GSV+N +M +T+ G
Sbjct: 182 PSPSDLTEFGRQLLAKDSNHPGSLGIAISDAVEYAHKN-GGKYVVGSVVNSDIMFKTIAG 240
Query: 252 LEAKEQMEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVL-DGKSEYEFIAVEPKAAPTMT 309
+EAK+QME E+PD IIG VGGGSN+A LAYPF+ D L GK ++IA P MT
Sbjct: 241 MEAKKQMELIGEDPDYIIGVVGGGSNYAALAYPFLGDELRSGKVRRKYIASGSSEVPKMT 300
Query: 310 RGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAY 369
+GVY YDY D+A L P LKM+T+G + PP++AGGLRYHG+APTLS+LI+ GIV+ Y
Sbjct: 301 KGVYKYDYPDTAKLLPMLKMYTIGSDFVPPPVYAGGLRYHGVAPTLSLLISKGIVQARDY 360
Query: 370 HQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLK 429
Q E F+ A LF++ EG +PAPE++HA+ + + A EA++ G+ +L + SGHGLLDL
Sbjct: 361 SQEESFKWAKLFSELEGYIPAPETSHALPILAEIAEEAKKSGERKTVLVSFSGHGLLDLG 420
Query: 430 GYEDYL 435
Y L
Sbjct: 421 NYASVL 426
>sp|Q9Y8T5|TRB1_AERPE TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|7437007|pir||E72488 probable
tryptophan synthase beta chain APE2548 - Aeropyrum
pernix (strain K1) >gi|5106254|dbj|BAA81565.1|
(AP000064) 427aa long hypothetical tryptophan synthase
beta chain [Aeropyrum pernix]
Length = 427
Score = 408 bits (1038), Expect = e-113
Identities = 222/422 (52%), Positives = 277/422 (65%), Gaps = 11/422 (2%)
Query: 21 IPRRWYNILPDLPEPLDPPLDPE-TEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELR 79
+P RWYNI DLPEPL P DPE E I L RI L++ E R+++IPGE+R
Sbjct: 4 VPLRWYNIAADLPEPLPPLRDPEGLREESRIALLSRILPSRLIEDEYILARWVDIPGEVR 63
Query: 80 KLYSKIGRPTPLFRATNLEKLLGTPAR--IYFKYEGATVTGSHKINTALAQAYYAKKQGI 137
K ++IGRPTPL RA LEK+LG R IY+K E TGSHKINTA+AQAYYAK G
Sbjct: 64 KALARIGRPTPLIRAEGLEKVLGVKGRVRIYYKSEAVLPTGSHKINTAIAQAYYAKLDGA 123
Query: 138 ERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSEN 197
+ +VTETGAGQWG A S A AL+GLK V+M +S++ K R+ LM GA V SPS+
Sbjct: 124 KEIVTETGAGQWGLAASTAAALMGLKATVFMTASSFKSKIQRRLLMEAQGARVISSPSKL 183
Query: 198 TEVGKRFLKE-DPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGLEAKE 256
T+ G+ L+E HPGSLG+AI+EA+E L+ RY GSVL VLMHQTVIGLEA +
Sbjct: 184 TDTGREALEEYGSTHPGSLGLAIAEAVEYTLESGDRRYLPGSVLEAVLMHQTVIGLEALD 243
Query: 257 QMEEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKS--EYEFIAVEPKAAPTMTRGVYT 314
Q+ E EPDV++ CVGGGSNF G YP + L G+ + FIA E AAP +TRG Y
Sbjct: 244 QLPE--EPDVVVACVGGGSNFGGFTYPMIGARLRGEGFEKTRFIAAESTAAPKLTRGEYR 301
Query: 315 YDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEV 374
YD DS+ + P KM+TLGHRY PP HA GLRYHG++P+LS+L G+V+ A Q E
Sbjct: 302 YDGLDSSLILPLAKMYTLGHRYTPPPSHAAGLRYHGVSPSLSILRRLGLVEAEAIPQEEA 361
Query: 375 FEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDY 434
+ +L A++EG+VPAPES+HAV A AR+ V+ FNLSGHGLLDL +
Sbjct: 362 LASILLMARSEGVVPAPESSHAVALA---ARIARKLPDGSVVAFNLSGHGLLDLDALQKA 418
Query: 435 LD 436
L+
Sbjct: 419 LE 420
>emb|CAC11807.1| (AL445065) tryptophan synthase, beta chain [Thermoplasma
acidophilum]
Length = 424
Score = 391 bits (994), Expect = e-108
Identities = 204/426 (47%), Positives = 284/426 (65%), Gaps = 8/426 (1%)
Query: 12 MKVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERY 71
+++ L +P WYNILPDLPE L P D ET E D LK+ ++++ E S ERY
Sbjct: 2 IRIDLKQDEMPDHWYNILPDLPEELPTPRD-ETGEAFDT--LKKAVPAKVLEYEFSGERY 58
Query: 72 IEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYY 131
+IP E+ + Y ++GRPTP+ RA LE+LLG +I+ K E T +GSHKIN+ALA ++
Sbjct: 59 PKIPDEILERYMQVGRPTPIIRAKKLEELLGGNLKIFLKMESYTYSGSHKINSALAHVFF 118
Query: 132 AKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVF 191
A+++G + + TETGAGQWG+A++LA AL ++ ++M R S+ KPYRK +M +YGA
Sbjct: 119 AREEGAKFVSTETGAGQWGSAVALASALFHMESHIFMVRTSFYAKPYRKYMMYMYGAHPH 178
Query: 192 PSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIG 251
PSPSE TE G+ LK P+ PGSLG+AISEAI L D +Y GSV+N ++ +T+ G
Sbjct: 179 PSPSEFTEYGREVLKRMPDTPGSLGLAISEAIHYAL-DNGGKYIAGSVINSDILFKTIAG 237
Query: 252 LEAKEQME-EFEEPDVIIGCVGGGSNFAGLAYPFVKDVL-DGKSEYEFIAVEPKAAPTMT 309
+EAK+QME E+PD I+G VGGGSN+A LA+PF+ D L GK +IA K P MT
Sbjct: 238 MEAKKQMEMAGEDPDYIVGVVGGGSNYAALAFPFLADELSSGKIRRTYIASGSKEVPKMT 297
Query: 310 RGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAY 369
G Y YDY D+ + P LKM+T+G+ + P ++AGGLRYH +APTLS+L+N GIV Y
Sbjct: 298 EGEYRYDYPDTGKVLPLLKMYTIGYDFIPPAVYAGGLRYHAVAPTLSLLMNKGIVSARDY 357
Query: 370 HQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLK 429
Q E F+ A +F++ EG +PAPE++HA+ I K + + G++ +L + SGHGLLDL
Sbjct: 358 DQEEAFKWARIFSETEGYIPAPETSHALP--ILKEIADKNRGEKKTVLVSFSGHGLLDLG 415
Query: 430 GYEDYL 435
Y + L
Sbjct: 416 NYAEAL 421
>sp|Q9YGB0|TRPB_PYRKO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|11269298|pir||T43927 tryptophan
synthase (EC 4.2.1.20) beta chain [imported] -
Pyrococcus kodakaraensis >gi|5545309|dbj|BAA82550.1|
(AB030011) beta subunit of tryptophan synthase
[Thermococcus kodakaraensis]
Length = 389
Score = 174 bits (437), Expect = 2e-42
Identities = 140/387 (36%), Positives = 191/387 (49%), Gaps = 43/387 (11%)
Query: 59 EELVKQEISRERYIEIP--GELRKLYSK--IGRPTPLFRATNLEKLLGTPARIYFKYEGA 114
E L K E + +++ + P E + Y + GRPTPL+ A L K LG A+IY K E
Sbjct: 20 EPLKKLERAYKKFKDDPEFNETLEYYLRNWAGRPTPLYYAERLSKKLGG-AKIYLKREDL 78
Query: 115 TVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQ 174
G+HK N + QA AK G ERL+ ETGAGQ G A ++AGALLG+KV VYM +
Sbjct: 79 LHGGAHKTNNGIGQALLAKFMGKERLIAETGAGQHGVATAMAGALLGMKVDVYMGAEDVE 138
Query: 175 QKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKAR 233
++ M + GA V P E G R LK+ AI+EA+ D V E +
Sbjct: 139 RQKMNVFRMGLLGARVIP-----VESGSRTLKD----------AINEALRDWVATFEYSH 183
Query: 234 YSLGSVLNH------VLMHQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFV 285
Y +GSV+ V Q+VIG EA+EQ+ E E PD ++ CVGGGSN G+ YPFV
Sbjct: 184 YLIGSVVGPYPYPVIVRDFQSVIGREAREQILEAEGTLPDAVVACVGGGSNAMGIFYPFV 243
Query: 286 KDVLDGKSEYEFIAVEPKAAPTMTRGVY--TYDYGDSAGLTPKLKMHTLGHRYYVPPIH- 342
D I VE + G++ + + G+ L + P H
Sbjct: 244 ND------RVRLIGVE-AGGKGLETGLHAASLNAGELGVFHGMLSYFLQNEEGQITPTHS 296
Query: 343 -AGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVI 401
+ GL Y G+ P + L + G + + E A ++ EGI+PA ESAHAV +
Sbjct: 297 VSAGLDYPGVGPEHAYLKDSGRAEYVTVTDEEALRAFHELSRTEGILPALESAHAVAYAM 356
Query: 402 DKALEARREGKEMVILFNLSGHGLLDL 428
A E K+ +I+ NLSG G DL
Sbjct: 357 KIAPEM---DKDEIIIVNLSGRGDKDL 380
>sp|O66923|TRB1_AQUAE TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|7436998|pir||G70361 tryptophan
synthase (EC 4.2.1.20) beta chain - Aquifex aeolicus
>gi|2983288|gb|AAC06880.1| (AE000703) tryptophan
synthase beta subunit [Aquifex aeolicus]
Length = 397
Score = 173 bits (434), Expect = 4e-42
Identities = 132/356 (37%), Positives = 178/356 (49%), Gaps = 38/356 (10%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL+ A L K +G A+IY K E TG+HKIN + Q K+ G +R++ ETG
Sbjct: 56 GRPTPLYFAEKLTKYVGG-AKIYLKREDLLHTGAHKINNTIGQCLLTKRMGKKRVIAETG 114
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A + A AL GL+ VYM +++ M++ GA+V E + G R L
Sbjct: 115 AGQHGVATATASALFGLECVVYMGEEDAERQALNVFRMKLLGAKV-----EIVKSGSRTL 169
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIGLEAKEQM 258
K+ AI+EA+ D V E Y +GSV+ V Q+VIG E KEQ+
Sbjct: 170 KD----------AINEALRDWVTNVESTHYVIGSVVGPHPFPMIVRDFQSVIGRETKEQI 219
Query: 259 --EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
+E PD I+ CVGGGSN G+ YPFV+D + I VE T
Sbjct: 220 LQKEGRLPDAIVACVGGGSNAMGIFYPFVED-----KGVQLIGVEAGGYGLETGQHAASI 274
Query: 317 YGDSAGLTPKLKMHTL-GHRYYVPPIH--AGGLRYHGLAPTLSVLINHGIVKPIAYHQTE 373
G S G+ +K + L + P H + GL Y G+ P ++ K E
Sbjct: 275 CGGSVGILHGMKSYFLQDEEGQIQPTHSISAGLDYPGVGPEHALFHEIKRAKYTTATDEE 334
Query: 374 VFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE-GKEMVILFNLSGHGLLDL 428
E L A+ EGI+PA ESAHAV KA+E RE GK+ +++ NLSG G D+
Sbjct: 335 ALEGFKLLARTEGIIPALESAHAV----IKAVEVARELGKDGIVVINLSGRGDKDM 386
>pir||F75162 tryptophan synthase, chain beta (trpb-1) PAB2048 - Pyrococcus
abyssi (strain Orsay) >gi|5457891|emb|CAB49381.1|
(AJ248284) tryptophan synthase, subunit beta (trpB-1)
[Pyrococcus abyssi]
Length = 388
Score = 173 bits (433), Expect = 5e-42
Identities = 136/360 (37%), Positives = 177/360 (48%), Gaps = 46/360 (12%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL+ A L K +G A+IY K E G+HK N A+ QA AK G RL+ ETG
Sbjct: 48 GRPTPLYYAERLTKKVGG-AKIYLKREDLLHGGAHKTNNAIGQALLAKFMGKTRLIAETG 106
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A ++AGALLG+KV +YM +++ M++ GA V P G + L
Sbjct: 107 AGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIP-----VHTGSKTL 161
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIGLEAKEQM 258
K+ AI+EA+ D V E + Y +GSV+ V Q+VIG EA+EQ+
Sbjct: 162 KD----------AINEALRDWVATFEYSHYLIGSVVGPHPYPIIVRDFQSVIGREAREQI 211
Query: 259 EEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------KAAPTM 308
E E PDVI+ CVGGGSN G+ YPFVKD I VE K + ++
Sbjct: 212 LEAEGDLPDVIVACVGGGSNAMGIFYPFVKD-----KSVRLIGVEAGGKGIESGKHSASL 266
Query: 309 TRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIA 368
G + G G+ G I A GL Y G+ P + L G + +
Sbjct: 267 NAG----EIGVFHGMLSYFLQDEEGQIRTTHSI-APGLDYPGVGPEHAYLKESGRAEYVT 321
Query: 369 YHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
E A ++ EGI+PA ESAHAV I A E R+ VI+ NLSG G DL
Sbjct: 322 VTDEEALRAFHELSRTEGIIPALESAHAVAYAIKLAREMSRDD---VIIVNLSGRGDKDL 378
>gi|11499193 tryptophan synthase, subunit beta (trpB-2) [Archaeoglobus fulgidus]
>gi|3334387|sp|O28672|TRB1_ARCFU TRYPTOPHAN SYNTHASE
BETA CHAIN 1 >gi|7437002|pir||G69449 tryptophan synthase
(EC 4.2.1.20) beta chain - Archaeoglobus fulgidus
>gi|2648960|gb|AAB89649.1| (AE000992) tryptophan
synthase, subunit beta (trpB-2) [Archaeoglobus fulgidus]
Length = 397
Score = 170 bits (426), Expect = 3e-41
Identities = 140/415 (33%), Positives = 198/415 (46%), Gaps = 67/415 (16%)
Query: 32 LPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPL 91
+PE L PPL+ E E+ D K F L E Y++ S GRPTPL
Sbjct: 24 VPEVLIPPLE-ELEKAYDRFKDDEEFKARL-------EYYLK---------SYAGRPTPL 66
Query: 92 FRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGT 151
+ A NL + LG +IY K E G+HKIN + QA AK G +R++ ETGAGQ G
Sbjct: 67 YFAENLSRELGV--KIYLKREDLLHGGAHKINNTIGQALLAKFMGKKRVIAETGAGQHGV 124
Query: 152 ALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNH 211
A ++A ALLGL+ +YM Y+++ M + GA+V E G R LK+
Sbjct: 125 ATAMAAALLGLEAEIYMGAEDYERQKMNVFRMELLGAKV-----TAVESGSRTLKD---- 175
Query: 212 PGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTVIGLEAKEQMEEFE-- 262
AI+EA+ D ++ E Y +GSV+ V Q VIG EA+ Q+ E E
Sbjct: 176 ------AINEALRDWVESFEHTHYLIGSVVGPHPFPTIVRDFQAVIGKEARRQIIEAEGG 229
Query: 263 EPDVIIGCVGGGSNFAGLAYPFVKDVL---------DGKSEYEFIAVEPKAAPTMTRGVY 313
PD II CVGGGSN G+ +PF+ D + +G A + + G+
Sbjct: 230 MPDAIIACVGGGSNAMGIFHPFLNDDVRLIGVEAGGEGIESGRHSASLTAGSKGVLHGML 289
Query: 314 TYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTE 373
+Y D G+ L H++ + GL Y G+ P + L G + + + E
Sbjct: 290 SYFLQDEEGM--MLDTHSV----------SAGLDYPGVGPEHAYLKETGRCEYVTVNDEE 337
Query: 374 VFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
A +K EGI+PA ESAHA+ + A E +R+ V++ NLSG G D+
Sbjct: 338 ALRAFKTLSKLEGIIPALESAHAIAYAMKMAEEMQRDD---VLVVNLSGRGDKDM 389
>pir||C81377 tryptophan synthase (EC 4.2.1.20) beta chain Cj0348 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967823|emb|CAB74185.1| (AL139075) tryptophan
synthase beta chain [Campylobacter jejuni]
Length = 392
Score = 165 bits (413), Expect = 1e-39
Identities = 134/379 (35%), Positives = 191/379 (50%), Gaps = 52/379 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
EL K Y +GRPTPL+ A NL K IY K E TG+HKIN A+AQA AKK G
Sbjct: 44 ELLKTY--VGRPTPLYFARNLSKKY--QHEIYLKREDLNHTGAHKINNAIAQALLAKKMG 99
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++++ ETGAGQ G A + A ALLGL+ +YM Q++ M + GA++ S
Sbjct: 100 KKKIIAETGAGQHGLATATAAALLGLECEIYMGATDVQRQALNVYKMELLGAKIHAVQS- 158
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEK-ARYSLGSVLN-----HVLMH-QTV 249
G + LKE A + AI+ + D K Y +GS + ++MH Q++
Sbjct: 159 ----GLKTLKE----------ATTAAIQAWVGDIKNIFYVVGSAVGPYPYPKMVMHFQSI 204
Query: 250 IGLEAKEQMEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE------- 301
IG E K Q+++ ++ D II VGGGSN AG+ Y F+KD + I +E
Sbjct: 205 IGKECKMQLQKLNKKVDYIIAAVGGGSNAAGIFYDFIKD-----ENVKLIGIEAGGLGID 259
Query: 302 -PKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIH--AGGLRYHGLAPTLSVL 358
P A T+ +G G G+ K+ LG+ + P+H + GL Y G+ P + L
Sbjct: 260 TPYHAATLNKG----KTGIIHGMKTKVLQDDLGN---ILPVHSVSAGLDYPGIGPLHAFL 312
Query: 359 INHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILF 418
+ A E +A L K EGI+ A ES+HA+ A ++K + K+ VI+
Sbjct: 313 FESKRAQYHAISDEECMQALKLLCKEEGIIAAIESSHAL-AFLEKLCPTLK--KKSVIVV 369
Query: 419 NLSGHGLLDLKGYEDYLDG 437
NLSG G D++ DY G
Sbjct: 370 NLSGRGDKDMQMIRDYKKG 388
>sp|Q60179|TRPB_METJA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|2118310|pir||D64429 tryptophan
synthase (EC 4.2.1.20) beta chain - Methanococcus
jannaschii >gi|1591690|gb|AAB99040.1| (U67546)
tryptophan synthase beta subunit (trpB) [Methanococcus
jannaschii]
Length = 404
Score = 164 bits (410), Expect = 2e-39
Identities = 140/408 (34%), Positives = 195/408 (47%), Gaps = 60/408 (14%)
Query: 42 PETEEPIDIEKLKRIFAEELVKQEIS-RERYIEIPGELRKLYSKIGRPTPLFRATNLEKL 100
PET P I +L+ F + E + RE + + L +GRPTPL+ A L +
Sbjct: 27 PETLMPA-IAELEEAFKRFWINNEGNFREEFYAL------LRDYVGRPTPLYYAERLSEE 79
Query: 101 LGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALL 160
LG ++Y K E G+HKIN AL QA AKK G +R++ ETGAGQ G A + A A L
Sbjct: 80 LG--CKVYLKREDLAHLGAHKINNALGQALLAKKMGKKRVIAETGAGQHGVATAAACAKL 137
Query: 161 GLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAIS 220
GL+ +YM +++ M + GA+V P G + LK+ A++
Sbjct: 138 GLECIIYMGAKDVERQKLNVFRMELMGAKVIP-----VFGGSQTLKD----------AVN 182
Query: 221 EAIEDVLKDEKAR-YSLGSVLN------HVLMHQTVIGLEAKEQMEEFEE--PDVIIGCV 271
EA+ D + + Y LGS L V Q VIG E KEQ+ E E PDVI+ CV
Sbjct: 183 EALRDWTTNVRTTYYLLGSALGPHPYPMMVREFQRVIGKELKEQILEKEGRLPDVIVACV 242
Query: 272 GGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMHT 331
GGGSN G Y F+ D + E AVE +G+ T +G S +H
Sbjct: 243 GGGSNAIGAFYEFLDD------DVELYAVEAGG-----KGIETGMHGASLCAGEVGVLH- 290
Query: 332 LGHRYYVPPIHAG----------GLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLF 381
G + YV G GL Y G+ P LS L + G +K + E EA L
Sbjct: 291 -GAKIYVKEDEFGQIEESYSISAGLDYPGVGPELSFLKDEGRIKAVCVTDDEALEAFQLL 349
Query: 382 AKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLK 429
+ EGI+PA ES+HA+ + A + K+ +++ NLSG G D++
Sbjct: 350 CRLEGILPALESSHALAYAVKL---ADKLDKDDIMVINLSGRGDKDVQ 394
>sp|P14638|TRPB_METVO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|150072|gb|AAA72854.1| (M35130)
tryptophan synthase B [Methanococcus voltae]
Length = 409
Score = 161 bits (404), Expect = 1e-38
Identities = 130/409 (31%), Positives = 200/409 (48%), Gaps = 55/409 (13%)
Query: 42 PETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLL 101
PE +P +E+LK + E ++ E + K Y+ GR TPL+ A NL + L
Sbjct: 22 PEVLKPA-VEELKEAYKELKDDEDFQNELAYYL-----KHYA--GRETPLYYAKNLTEKL 73
Query: 102 GTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLG 161
G A+IY K E G+HK N + QA AKK G R++ ETGAGQ G S+AGAL G
Sbjct: 74 GG-AKIYLKREDLLHGGAHKTNNTIGQALLAKKMGKTRIIAETGAGQHGVGTSMAGALFG 132
Query: 162 LKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISE 221
L+ ++M R +++ M++ GA+V P + G + LK+ A++E
Sbjct: 133 LETEIFMGRVDTERQQPNVARMKLLGAKVTP-----VDTGSKVLKD----------AVNE 177
Query: 222 AIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQMEEFEE--PDVIIGCVG 272
A+ + E Y LG+V+ V Q+VIG E K+Q+ E EE PD ++ C+G
Sbjct: 178 AMRNWTATFENTHYLLGTVMGPHPFPTMVRDFQSVIGKEVKKQIMEQEERLPDYLVACIG 237
Query: 273 GGSNFAGLAYPFVKDVL----DGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLK 328
GGSN GL +PF+ + + D + I +E +G+ T +G S K
Sbjct: 238 GGSNAMGLFHPFLSNNISTGNDDAKNVKMIGIEAAG-----KGLNTSLHGASITKGEKGV 292
Query: 329 MHTLGHRYYVPPIH---------AGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAV 379
+H + Y++ + GL Y G+ P + L N G V+ + + +A +
Sbjct: 293 LHGM-LSYFLQDEDGQIEEAYSISAGLDYPGIGPEHAYLHNLGRVQYASATDKQALKAFM 351
Query: 380 LFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
+ EGI+PA ES+HA+ I+ A K+ +++ NLSG G DL
Sbjct: 352 ELTRTEGIIPALESSHAIAYAIE---NAGNMDKDDIMVINLSGRGDKDL 397
>sp|P19868|TRPB_BACST TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80229|pir||JT0524 tryptophan
synthase (EC 4.2.1.20) beta chain - Bacillus
stearothermophilus >gi|216354|dbj|BAA00427.1| (D00539)
tryptophan synthase beta-subunit [Bacillus
stearothermophilus]
Length = 404
Score = 161 bits (403), Expect = 2e-38
Identities = 147/424 (34%), Positives = 201/424 (46%), Gaps = 64/424 (15%)
Query: 32 LPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPL 91
+PE L PL+ E E +D + A+E KQE YI I L GRPTPL
Sbjct: 19 VPETLMLPLE-EIEAELD-----KALADESFKQE-----YIRI------LQHYSGRPTPL 61
Query: 92 FRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGT 151
A NL + LG A++Y K E TG+HKIN A+ QA AK+ G ++L+ ETGAGQ G
Sbjct: 62 TFAPNLTRQLGG-AKMYLKREDLNHTGAHKINNAIGQALLAKRMGKKKLIAETGAGQHGV 120
Query: 152 ALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNH 211
A + A G+ V+M +++ M++ GAEV P S G R LK+
Sbjct: 121 AAATVAAHFGMDCIVFMGEEDIKRQELNVFRMKLLGAEVVPVSS-----GNRTLKD---- 171
Query: 212 PGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQME--EFE 262
A +EAI V + Y +GSV+ V Q +IG EAKEQ E +
Sbjct: 172 ------ATNEAIRYWVAHCDDHFYMIGSVVGPHPYPKMVREFQRIIGDEAKEQFLACEGK 225
Query: 263 EPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE--------PKAAPTMTRGVYT 314
PDVI+ CVGGGSN G+ YPF++D + + VE P A T+T+G
Sbjct: 226 LPDVIVACVGGGSNAIGMFYPFLQD------DVRLVGVEAAGKGIDTPYHAATITKGT-- 277
Query: 315 YDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEV 374
G G L G + P + GL Y G+ P + L + G V+ + E
Sbjct: 278 --KGVIHGAMTYLLQDEYG-QIVEPYSISAGLDYPGVGPEHAYLASIGRVRYESVTDEEA 334
Query: 375 FEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDY 434
A L A+ EGI+PA ESAHAV ++ A+ + +L LSG G D++ +
Sbjct: 335 VAAFRLLAQTEGIIPAIESAHAVAKAVEL---AQSMSPDETVLICLSGRGDKDVQTMMRH 391
Query: 435 LDGK 438
L K
Sbjct: 392 LGAK 395
>prf||1603216A Trp synthase [Bacillus stearothermophilus]
Length = 404
Score = 161 bits (403), Expect = 2e-38
Identities = 147/424 (34%), Positives = 201/424 (46%), Gaps = 64/424 (15%)
Query: 32 LPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPL 91
+PE L PL+ E E +D + A+E KQE YI I L GRPTPL
Sbjct: 19 VPETLMLPLE-EIEAELD-----KALADESFKQE-----YIRI------LQHYSGRPTPL 61
Query: 92 FRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGT 151
A NL + LG A++Y K E TG+HKIN A+ QA AK+ G ++L+ ETGAGQ G
Sbjct: 62 TFAPNLTRQLGG-AKMYLKREDLNHTGAHKINNAIGQALLAKRMGKKKLIAETGAGQHGV 120
Query: 152 ALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNH 211
A + A G+ V+M +++ M++ GAEV P S G R LK+
Sbjct: 121 AAATVAAHFGMDCIVFMGEEDIKRQELNVFRMKLLGAEVVPVSS-----GNRTLKD---- 171
Query: 212 PGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQME--EFE 262
A +EAI V + Y +GSV+ V Q +IG EAKEQ E +
Sbjct: 172 ------ATNEAIRYWVAHCDDHFYMIGSVVGPHPYPKMVREFQRIIGDEAKEQFLACEGK 225
Query: 263 EPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE--------PKAAPTMTRGVYT 314
PDVI+ CVGGGSN G+ YPF++D + + VE P A T+T+G
Sbjct: 226 LPDVIVACVGGGSNAIGMFYPFLQD------DVRLVGVEAAGKGIDTPYHAATITKGT-- 277
Query: 315 YDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEV 374
G G L G + P + GL Y G+ P + L + G V+ + E
Sbjct: 278 --KGVIHGAMTYLLQDEYG-QIVEPYSISAGLDYPGVGPEHAYLASIGRVRYESVTDEEA 334
Query: 375 FEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDY 434
A L A+ EGI+PA ESAHAV ++ A+ + +L LSG G D++ +
Sbjct: 335 VAAFRLLAQTEGIIPAIESAHAVAKAVEL---AQSMSPDETVLICLSGRGDKDVQTMMRH 391
Query: 435 LDGK 438
L K
Sbjct: 392 LGAK 395
>sp|P56929|TRPB_RHIET TRYPTOPHAN SYNTHASE BETA CHAIN >gi|5834681|emb|CAB55324.1|
(AJ245564) tryptophan synthase beta subunit [Rhizobium
etli]
Length = 406
Score = 159 bits (397), Expect = 8e-38
Identities = 126/363 (34%), Positives = 171/363 (46%), Gaps = 50/363 (13%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
IGRP+PL+ A L LG A+IYFK E TGSHKIN + Q AK+ G R++ ET
Sbjct: 64 IGRPSPLYFAERLTAELGG-AKIYFKREDMNHTGSHKINNCIGQILLAKRMGKTRIIAET 122
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAGQ G A + A GL VYM +++ M++ GAEV P + +
Sbjct: 123 GAGQHGVASAAVAARFGLPCMVYMGATDVERQAPNVFRMKLLGAEVKPMTAGS------- 175
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQ 257
G+L A++EA+ D V E Y +G+ V Q++IG EAKEQ
Sbjct: 176 --------GTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSMIGAEAKEQ 227
Query: 258 M--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVL----------DGKSEYEFIAVEPKAA 305
M E PD+++ VGGGSN G+ +PF+ D G E A +
Sbjct: 228 MLAAEGRLPDLVVAAVGGGSNAIGIFHPFLDDSSMKIVGVEAGGKGLQGDEHCASITAGS 287
Query: 306 PTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVK 365
P + G TY D G + GH + GL Y G+ P S L + G V
Sbjct: 288 PGVLHGNRTYLLQDGDGQIKE------GHSI------SAGLDYPGIGPEHSWLSDIGRVD 335
Query: 366 PIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGL 425
+ E EA + EGI+PA E+AHA+ VI + A + GK+ +IL NLSG G
Sbjct: 336 YMPIMDHEALEAFQTLTRLEGIIPALEAAHAIAEVIKR---APKMGKDEIILMNLSGRGD 392
Query: 426 LDL 428
D+
Sbjct: 393 KDI 395
>sp|O08376|TRPB_MYCTU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7436999|pir||B70557 tryptophan
synthase (EC 4.2.1.20) beta chain - Mycobacterium
tuberculosis (strain H37RV) >gi|2113896|emb|CAB08906.1|
(Z95554) trpB [Mycobacterium tuberculosis]
Length = 410
Score = 157 bits (392), Expect = 3e-37
Identities = 128/399 (32%), Positives = 188/399 (47%), Gaps = 57/399 (14%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYF 109
IE++ + +E V Q+ +++ L+ Y+ GRP+PL+ AT L + G+ ARI+
Sbjct: 38 IEEVTAAYQKERVSQD-----FLDDLDRLQANYA--GRPSPLYEATRLSQHAGS-ARIFL 89
Query: 110 KYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMA 169
K E TGSHKIN L QA A++ G R++ ETGAGQ G A + A ALLGL +YM
Sbjct: 90 KREDLNHTGSHKINNVLGQALLARRMGKTRVIAETGAGQHGVATATACALLGLDCVIYMG 149
Query: 170 RASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLK 228
++ MR+ GAEV + G + LK+ AI+EA D V
Sbjct: 150 GIDTARQALNVARMRLLGAEVVA-----VQTGSKTLKD----------AINEAFRDWVAN 194
Query: 229 DEKARYSLGSVL------NHVLMHQTVIGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGL 280
+ Y G+ V Q +IG+EA+ Q+ + PD ++ CVGGGSN G+
Sbjct: 195 ADNTYYCFGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLPDAVVACVGGGSNAIGI 254
Query: 281 AYPFVKD----------VLDGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMH 330
+ F+ D DG A +P G ++Y D G T ++ H
Sbjct: 255 FHAFLDDPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYLLQDEDGQT--IESH 312
Query: 331 TLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPA 390
++ + GL Y G+ P + L G V +E +A L + EGI+PA
Sbjct: 313 SI----------SAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAMDAFGLLCRMEGIIPA 362
Query: 391 PESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLK 429
ESAHAV + +E G+ VI+ NLSG G D++
Sbjct: 363 IESAHAVAGALKLGVEL---GRGAVIVVNLSGRGDKDVE 398
>sp|P50909|TRB1_THEMA TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|2120373|pir||S59049 tryptophan
synthase (EC 4.2.1.20) beta chain - Thermotoga maritima
(strain MSB8) >gi|1054861|emb|CAA63391.1| (X92729)
tryptophan synthase beta-subunit [Thermotoga maritima]
>gi|4980630|gb|AAD35231.1|AE001699_8 (AE001699)
tryptophan synthase, beta subunit [Thermotoga maritima]
Length = 389
Score = 155 bits (389), Expect = 7e-37
Identities = 135/398 (33%), Positives = 194/398 (47%), Gaps = 60/398 (15%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYF 109
+E+L+ + EE++K E + + ++ L GRPTPL+ A L + G ARIY
Sbjct: 21 LEELEAAY-EEIMKDESFWKEFNDL------LRDYAGRPTPLYFARRLSEKYG--ARIYL 71
Query: 110 KYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMA 169
K E TG+HKIN A+ Q AKK G R++ ETGAGQ G A + A AL G++ +YM
Sbjct: 72 KREDLLHTGAHKINNAIGQVLLAKKMGKTRIIAETGAGQHGVATATAAALFGMECVIYMG 131
Query: 170 RA-SYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLK 228
+ +QKP M++ GA+V P S G R LK+ AI+EA+ D +
Sbjct: 132 EEDTIRQKP-NVERMKLLGAKVVPVKS-----GSRTLKD----------AINEALRDWIT 175
Query: 229 D-EKARYSLGSVLNH------VLMHQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAG 279
+ + Y +GSV+ V Q VIG E K+Q+ E E PD I+ CVGGGSN AG
Sbjct: 176 NLQTTYYVIGSVVGPHPYPIIVRNFQKVIGEETKKQILEKEGRLPDYIVACVGGGSNAAG 235
Query: 280 LAYPFVKDVLDGKSEYEFIAVEP--------KAAPTMTRGVYTYDYGDSAGLTPKLKMHT 331
+ YPF+ S + I VE K A ++ +G Y +G +
Sbjct: 236 IFYPFI------DSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKT-----FVLQD 284
Query: 332 LGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAP 391
+ V + GL Y G+ P + G V A E +A + ++ EGI+PA
Sbjct: 285 DWGQVQVTHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPAL 344
Query: 392 ESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLK 429
ES+HA+ A + K V++ NLSG G DL+
Sbjct: 345 ESSHAL------AYLKKINIKGKVVVVNLSGRGDKDLE 376
>sp|P26921|TRPB_METTM TRYPTOPHAN SYNTHASE BETA CHAIN >gi|99120|pir||B40362 tryptophan
synthase (EC 4.2.1.20) beta chain - Methanobacterium
thermoautotrophicum (strain Marburg)
>gi|149749|gb|AAA73032.1| (M65060) tryptophan synthase
beta-subunit [Methanobacterium thermoautotrophicum]
Length = 390
Score = 155 bits (387), Expect = 1e-36
Identities = 125/362 (34%), Positives = 169/362 (46%), Gaps = 51/362 (14%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPT L+ A NL + LG R+Y K E TG+HKIN + QA A G RL+ ETG
Sbjct: 50 GRPTGLYHARNLSEKLG--CRVYLKREDMLHTGAHKINNTIGQALLAGYMGKRRLIAETG 107
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A + AGAL G+ V VYM +++ M I GA V P S G R L
Sbjct: 108 AGQHGIATAAAGALFGMDVDVYMGTEDVERQKLNVFRMEISGARVIPVDS-----GSRTL 162
Query: 206 KEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVL------NHVLMHQTVIGLEAKEQM 258
K+ AI++A+ D + E Y +GS + V Q+VIG EA+EQ+
Sbjct: 163 KD----------AINQAMRDWISSVEDTHYLIGSTMGPHPYPTMVKHFQSVIGREAREQI 212
Query: 259 EEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
E E PD II CVGGGSN G+ F+ D + E I E G+ + +
Sbjct: 213 LEIEGELPDTIIACVGGGSNAIGIFSAFLDD------DVELIGAEGGG-----EGIESGN 261
Query: 317 YGDSAGLTPKLKMHTLGHRYYVPPIHAG----------GLRYHGLAPTLSVLINHGIVKP 366
+G + + +H G YV G GL Y G+ P + L+ G
Sbjct: 262 HGATLSAGSEGVLH--GSLSYVLQDDDGQINEAHSVSAGLDYPGVGPEHAYLMETGRAMY 319
Query: 367 IAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLL 426
E L ++ EGI+PA ESAHA+ + A + GK +++ NLSG G
Sbjct: 320 EPITDAEALRGFKLLSRCEGIMPALESAHAIACLEKYASKPENRGKTVIV--NLSGRGDK 377
Query: 427 DL 428
D+
Sbjct: 378 DM 379
>sp|O27696|TRB1_METTH TRYPTOPHAN SYNTHASE BETA CHAIN 1 >gi|7437001|pir||G69088 tryptophan
synthase (EC 4.2.1.20) beta chain - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622787|gb|AAB86131.1| (AE000924) tryptophan
synthase, beta subunit [Methanobacterium
thermoautotrophicum]
Length = 392
Score = 155 bits (387), Expect = 1e-36
Identities = 130/398 (32%), Positives = 191/398 (47%), Gaps = 58/398 (14%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYF 109
+E+L+R F + R+ E+ LR+ G+PT L+ A NL + LG R+Y
Sbjct: 23 LEELERAF----LHYRDDRKFMAELEYHLREY---AGKPTGLYYARNLSEKLG--CRVYL 73
Query: 110 KYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMA 169
K E TG+HKIN + QA A+ G R++ ETGAGQ G A + AGAL G+ V +YM
Sbjct: 74 KREDMLHTGAHKINNTIGQALLARYMGKTRIIAETGAGQHGIATAAAGALFGMDVDIYMG 133
Query: 170 RASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD 229
+++ M + GAEV P S G R LK+ AI+EA+ D + +
Sbjct: 134 TEDVERQKLNVFRMEVSGAEVIPVDS-----GSRTLKD----------AINEAMRDWISN 178
Query: 230 -EKARYSLGSVL------NHVLMHQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGL 280
+ Y +GS + V Q+VIG EA+EQ+ E E PD +I CVGGGSN G+
Sbjct: 179 VDDTHYLIGSTMGPHPYPTMVKHFQSVIGREAREQILEVEGELPDTVIACVGGGSNAIGI 238
Query: 281 AYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYV-- 338
F+ D + E I E G+ + ++G + + +H G YV
Sbjct: 239 FSAFMDD------DVELIGAEGGG-----EGIESGNHGATLSAGSEGILH--GSLSYVLQ 285
Query: 339 ------PPIH--AGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPA 390
H + GL Y G+ P + L++ G + TE L ++ EGI+PA
Sbjct: 286 DGDGQISEAHSVSAGLDYPGVGPEHAHLMDTGRARYEPVTDTEALRGFRLLSRYEGIMPA 345
Query: 391 PESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
ESAHA+ + A + GK +++ NLSG G D+
Sbjct: 346 LESAHAIACLERYAEKPENRGKTVIV--NLSGRGDKDM 381
>sp|P16609|TRPB_THETH TRYPTOPHAN SYNTHASE BETA CHAIN >gi|94734|pir||A35407 tryptophan
synthase (EC 4.2.1.20) beta chain - Thermus aquaticus
>gi|155133|gb|AAA27508.1| (M32108) tryptophan synthetase
B (EC 4.2.1.20) [Thermus thermophilus]
Length = 404
Score = 153 bits (383), Expect = 4e-36
Identities = 126/367 (34%), Positives = 177/367 (47%), Gaps = 36/367 (9%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL+ A L + G A+++ K E TG+HKIN L QA A++ G R++ ETG
Sbjct: 61 GRPTPLYHAKRLSEYWGG-AQVFLKREDLLHTGAHKINNTLGQALLARRMGKRRVIAETG 119
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G +++ AL GL+ VYM +++ M++ GAEV P G R L
Sbjct: 120 AGQHGVSVATVAALFGLECVVYMGEEDVRRQALNVFRMKLLGAEVRP-----VAAGSRTL 174
Query: 206 KEDPNHPGSLGIAISEAIEDVLKDEKAR-YSLGSVLN------HVLMHQTVIGLEAKEQM 258
K+ A +EAI D + + + Y LGSV+ V Q+VIG E K Q
Sbjct: 175 KD----------ATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQS 224
Query: 259 EEF--EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
E PD +I VGGGSN GL PF + +G+ + I VE A ++ G +
Sbjct: 225 LELFGRLPDALIAAVGGGSNAIGLFAPFAY-LPEGRP--KLIGVE-AAGEGLSTGRHAAS 280
Query: 317 YG-DSAGLTPKLKMHTL-GHRYYVPPIH--AGGLRYHGLAPTLSVLINHGIVKPIAYHQT 372
G G+ M+ L H + P H + GL Y G+ P S + G+ + +
Sbjct: 281 IGAGKRGVLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDE 340
Query: 373 EVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYE 432
E E L A+ EGI+PA ESAHA+ E K+ V++ NLSG G D+
Sbjct: 341 EALEGFKLLARLEGIIPALESAHAIAYAAKVVPEM---DKDQVVVINLSGRGDKDVTEVM 397
Query: 433 DYLDGKL 439
L G+L
Sbjct: 398 RLLGGEL 404
>pir||B81169 tryptophan synthase, beta chain NMB0699 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225927|gb|AAF41116.1| (AE002424) tryptophan
synthase, beta subunit [Neisseria meningitidis MC58]
Length = 400
Score = 152 bits (379), Expect = 1e-35
Identities = 124/364 (34%), Positives = 176/364 (48%), Gaps = 51/364 (14%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
+GRP+P++ A L + LG A+I+ K E TG+HK+N + QA AK+ G +R++ ET
Sbjct: 57 VGRPSPVYHAARLSEHLGG-AQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAET 115
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAGQ G A + A G+ VYM Q++ M++ GA V E G R
Sbjct: 116 GAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGANVV-----GVESGSRT 170
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQ 257
LK+ A++EA+ + V + + Y +G+ V Q VIG EAK Q
Sbjct: 171 LKD----------AMNEAMREWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQ 220
Query: 258 MEEF--EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTY 315
M+E +PDV + CVGGGSN GL +P++ G+ + VE GV T
Sbjct: 221 MQEAIGRQPDVAVACVGGGSNAIGLFHPYI-----GEENVRLVGVEAGGL-----GVNTP 270
Query: 316 DYGDSAGLTPKLKMHTL-GHRYYVPPIHAG----------GLRYHGLAPTLSVLINHGIV 364
D+ +A +T + L G R Y+ G GL Y G+ P S L + V
Sbjct: 271 DH--AAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHSHLHDIKRV 328
Query: 365 KPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHG 424
+ E EA L + EGI+PA ES+HAV + A + GK+ VIL NLSG G
Sbjct: 329 EYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVK---NAPKMGKDQVILVNLSGRG 385
Query: 425 LLDL 428
D+
Sbjct: 386 DKDI 389
>pir||H81936 probable tryptophan synthase (EC 4.2.1.20) beta chain NMA0904
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7379616|emb|CAB84181.1| (AL162754) putative
tryptophan synthase beta chain [Neisseria meningitidis
Z2491]
Length = 400
Score = 152 bits (379), Expect = 1e-35
Identities = 124/364 (34%), Positives = 176/364 (48%), Gaps = 51/364 (14%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
+GRP+P++ A L + LG A+I+ K E TG+HK+N + QA AK+ G +R++ ET
Sbjct: 57 VGRPSPVYHAARLSEHLGG-AQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAET 115
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAGQ G A + A G+ VYM Q++ M++ GA V E G R
Sbjct: 116 GAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGANVV-----GVESGSRT 170
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQ 257
LK+ A++EA+ + V + + Y +G+ V Q VIG EAK Q
Sbjct: 171 LKD----------AMNEAMREWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQ 220
Query: 258 MEEF--EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTY 315
M+E +PDV + CVGGGSN GL +P++ G+ + VE GV T
Sbjct: 221 MQEAIGRQPDVAVACVGGGSNAIGLFHPYI-----GEENVRLVGVEAGGL-----GVNTP 270
Query: 316 DYGDSAGLTPKLKMHTL-GHRYYVPPIHAG----------GLRYHGLAPTLSVLINHGIV 364
D+ +A +T + L G R Y+ G GL Y G+ P S L + V
Sbjct: 271 DH--AAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHSHLHDIKRV 328
Query: 365 KPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHG 424
+ E EA L + EGI+PA ES+HAV + A + GK+ VIL NLSG G
Sbjct: 329 EYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVK---NAPKMGKDQVILVNLSGRG 385
Query: 425 LLDL 428
D+
Sbjct: 386 DKDI 389
>gb|AAF61457.1|AF139661_2 (AF139661) tryptophan synthase beta subunit [Azospirillum
brasilense]
Length = 405
Score = 151 bits (378), Expect = 1e-35
Identities = 123/379 (32%), Positives = 181/379 (47%), Gaps = 48/379 (12%)
Query: 80 KLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIER 139
+L +GRP PL+ A L + LG A+IYFK E TG+HKIN + Q A++ G +R
Sbjct: 56 QLKQYVGRPNPLYYAERLTEKLGG-AKIYFKREELNHTGAHKINNCIGQILLARRMGKKR 114
Query: 140 LVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTE 199
++ ETGAGQ G A + AL + +YM ++ M++ GAEV P S
Sbjct: 115 IIAETGAGQHGVATATVCALFDMPCVIYMGETDIARQQPNVFRMKLLGAEVVPVTS---- 170
Query: 200 VGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGL 252
G R LK+ A++EA+ D V Y +G+ V Q+VIG
Sbjct: 171 -GARTLKD----------AMNEALRDWVTNVADTYYLIGTAAGPHPYPAMVRDFQSVIGD 219
Query: 253 EAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTR 310
E + QM+E E PD ++ CVGGGSN GL +PF+ D + +AVE
Sbjct: 220 EVRVQMQELEGRLPDSLVACVGGGSNAIGLFHPFLDD-----PSVQMVAVEAAG-----H 269
Query: 311 GVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAG----------GLRYHGLAPTLSVLIN 360
G+ +A +T G+R Y+ G GL Y G+ P S L +
Sbjct: 270 GIDKGPLAHAASITGGRPGVLHGNRTYLLQDEDGQILEGHSISAGLDYPGVGPEHSWLHD 329
Query: 361 HGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNL 420
G V+ ++ E +A L A+ EGI+PA ESAHA+ ++ + A + K+ +++ L
Sbjct: 330 IGRVEYVSATDQETLDAFQLCARTEGIIPALESAHALAEIVKR---APKLPKDHLMVLCL 386
Query: 421 SGHGLLDLKGYEDYLDGKL 439
SG G D+ +L KL
Sbjct: 387 SGRGDKDIFSVAQHLGVKL 405
>pir||D75455 tryptophan synthase, beta subunit - Deinococcus radiodurans
(strain R1) >gi|6458666|gb|AAF10518.1|AE001947_1
(AE001947) tryptophan synthase, beta subunit
[Deinococcus radiodurans]
Length = 431
Score = 151 bits (378), Expect = 1e-35
Identities = 136/410 (33%), Positives = 186/410 (45%), Gaps = 51/410 (12%)
Query: 32 LPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPL 91
+PE L P LD E E+ + K F +EL R L +GRP L
Sbjct: 38 VPETLIPALD-ELEQAYEAAKQDPEFLDELD----------------RLLREFVGRPNSL 80
Query: 92 FRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGT 151
+ A L + G A+IY K E TG+HKIN LAQA AK+ G ++++ ETGAGQ G
Sbjct: 81 YLAERLTEHAGG-AKIYLKREDQNFTGAHKINNCLAQALLAKRMGKQKIIAETGAGQHGV 139
Query: 152 ALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNH 211
A + A ALLGL VYM +++ M++ GAEV P S G LK+ N
Sbjct: 140 ASATAAALLGLSCVVYMGEEDMRRQSLNVFRMQLLGAEVRPVTS-----GTATLKDATNE 194
Query: 212 PGSLGIAISEAIEDVLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQMEEFE--- 262
AI E + +V Y LGSV+ V Q+VIG E K Q++E E
Sbjct: 195 ------AIREWVTNV---RDTFYILGSVVGPHPYPAMVRDFQSVIGEEVKVQLQEKEGRS 245
Query: 263 EPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDYG-DSA 321
PD I+ CVGGGSN G+ PF L I E A + G++
Sbjct: 246 VPDAIVACVGGGSNAIGIFAPFA--YLPEGERPRLIGTE-AAGHGVDTGMHAASVAWGRV 302
Query: 322 GLTPKLKMHTLG--HRYYVPPIH-AGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAA 378
G+ M+ + VPP + GL Y G+ P G+ + + + E
Sbjct: 303 GVLHGSMMYLMNDDEGQIVPPHSISAGLDYPGIGPEHCYYSVMGMAEYVPVTDAQALEGL 362
Query: 379 VLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
L + EGI+PA ESAHA+ + AR+ E +++ NLSG G D+
Sbjct: 363 QLLTRLEGIIPALESAHAISYAVQL---ARQMKPEEIVVVNLSGRGDKDV 409
>sp|Q01998|TRPB_LACLA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|421430|pir||S35129 tryptophan
synthase (EC 4.2.1.20) beta chain - Lactococcus lactis
subsp. lactis >gi|149521|gb|AAA25228.1| (M87483)
tryptophan synthase beta subunit [Lactococcus lactis]
Length = 402
Score = 150 bits (376), Expect = 2e-35
Identities = 126/376 (33%), Positives = 175/376 (46%), Gaps = 38/376 (10%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
EL K Y +GR PL+ A L + G A+IY K E TG+HKIN AL Q AKK G
Sbjct: 50 ELLKDY--VGRENPLYYAKRLTEYAGG-AKIYLKREDLNHTGAHKINNALGQVLLAKKMG 106
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
+++ ETGAGQ G A + A AL G++ +YM +++ M + GA+V
Sbjct: 107 KNKVIAETGAGQHGVASATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKV-----H 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTV 249
+ G R LK+ A++ A+ V + E Y +GSVL V +Q V
Sbjct: 162 SVTDGSRVLKD----------AVNAALRAWVAQVEDTHYVMGSVLGPHPFPQIVRDYQAV 211
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKD---VLDGKSEYEFIAVEPKA 304
IG EA+ Q E E PD ++ CVGGGSN GL YPFV D + G P
Sbjct: 212 IGQEARAQFLEKENKLPDALVACVGGGSNSMGLFYPFVNDESVAMYGVEAAGLGIDTPHH 271
Query: 305 APTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIV 364
A T+T+G G G + G I A GL Y G+ P S G
Sbjct: 272 AATITKG----RPGVLHGTLMDVLQDENGQMLEAFSISA-GLDYPGIGPEHSYFNAVGRA 326
Query: 365 KPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHG 424
K + E E + ++ EGI+PA ES+HA+ + A E G + ++ LSG G
Sbjct: 327 KYVDITDEEALEGFKILSRTEGIIPALESSHAIAYAVKLAKEL---GADKSMIVCLSGRG 383
Query: 425 LLDLKGYEDYLDGKLE 440
D+ ++ L+ + E
Sbjct: 384 DKDVVQVKERLEAEKE 399
>sp|O68905|TRPB_MYCIT TRYPTOPHAN SYNTHASE BETA CHAIN >gi|3152733|gb|AAC17134.1|
(AF057042) tryptophan synthase beta subunit
[Mycobacterium intracellulare]
Length = 421
Score = 150 bits (376), Expect = 2e-35
Identities = 132/438 (30%), Positives = 194/438 (44%), Gaps = 77/438 (17%)
Query: 30 PDLPEPLDPPLDPETEEP-------------------IDIEKLKRIFAEELVKQEISRER 70
PDLP P +P EP IE++ + +E V Q+
Sbjct: 9 PDLPLPSAAIAEPTRHEPDAGGHFGVYGGRYVAEALMAVIEEVTTAYEKERVNQD----- 63
Query: 71 YIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAY 130
+++ L+ Y+ GRP+PL+ A L + G ARI+ K E TGSHKIN L QA
Sbjct: 64 FLDTLDYLQANYA--GRPSPLYEAPRLSEQAG--ARIFLKREDLNHTGSHKINNVLGQAL 119
Query: 131 YAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEV 190
A++ G +R++ ETGAGQ G A + A ALLGL+ +YM +++ MR+ GA V
Sbjct: 120 LAQRMGKKRVIAETGAGQHGVATATACALLGLECVIYMGAVDTERQALNVARMRLLGATV 179
Query: 191 FPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HV 243
+ + G + LK+ AI+EA D V + Y G+ V
Sbjct: 180 V-----SVQSGSKTLKD----------AINEAFRDWVTNADNTFYCFGTAAGPHPFPAMV 224
Query: 244 LMHQTVIGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKD----------VLDG 291
Q +IGLEA+ Q+ + PD ++ C+GGGSN G+ +PF+ D DG
Sbjct: 225 RDFQRIIGLEARAQIQAQAGRLPDAVLACIGGGSNAIGIFHPFIDDPGVRLIGFEAAGDG 284
Query: 292 KSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGL 351
A +P +G ++Y D G T ++ H++ + GL Y G+
Sbjct: 285 VETGRHAATFSGGSPGAFQGSFSYLLQDEDGQT--IESHSI----------SAGLDYPGV 332
Query: 352 APTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG 411
P + L T + EGI+PA ESAHAV + A E G
Sbjct: 333 GPEHAWLRERVSTTRGWVRNTRGCARFRTLCRTEGIIPAIESAHAVAGALKVAPEL---G 389
Query: 412 KEMVILFNLSGHGLLDLK 429
K +I+ NLSG G D++
Sbjct: 390 KAAIIVVNLSGRGDKDVE 407
>sp|P12290|TRPB_CAUCR TRYPTOPHAN SYNTHASE BETA CHAIN >gi|279952|pir||C43664 tryptophan
synthase (EC 4.2.1.20) beta chain - Caulobacter
crescentus >gi|144287|gb|AAA23057.1| (M19129) tryptophan
synthase B protein (trpB; gtg start codon; EC 4.2.1.20)
[Caulobacter crescentus]
Length = 406
Score = 150 bits (375), Expect = 3e-35
Identities = 123/373 (32%), Positives = 177/373 (46%), Gaps = 50/373 (13%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRP+PL+ A L + G A+IYFK + TGSHKIN AL Q A + G R++ ETG
Sbjct: 65 GRPSPLYFAERLTEHFGG-AKIYFKRDELNHTGSHKINNALGQILLAMRMGKTRIIAETG 123
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A + A GL VYM +++ M + GAEV P S
Sbjct: 124 AGQHGVATATVCARFGLPCVVYMGATDVERQKPNVFRMNLLGAEVRPVSSGT-------- 175
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQM 258
G+L A++EA+ D V Y +G+ V Q+VIG EA+EQ+
Sbjct: 176 -------GTLKDAMNEAMRDWVTNVHDTYYLIGTAAGPHPYPVMVRDFQSVIGAEAREQI 228
Query: 259 EEFEE--PDVIIGCVGGGSNFAGLAYPFVKD----VLDGKSEYEFIAVEPKAA------P 306
E E PD ++ C+GGGSN GL +PF+ D ++ ++ ++ + AA P
Sbjct: 229 LEMEGRLPDAVVACIGGGSNAIGLFHPFLGDEGVRLIGVEAAGHGVSTDKHAASLTGGRP 288
Query: 307 TMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKP 366
+ G TY D G + H++ + GL Y G+ P S L + G +
Sbjct: 289 GVLHGNRTYLLQDDDGQI--IDAHSI----------SAGLDYPGIGPEHSFLHDIGRAEY 336
Query: 367 IAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLL 426
++ TE EA L + EGI+PA E AHA+ V + A E GK +++ NL G G
Sbjct: 337 VSTTDTEALEAFKLCSTLEGIIPALEPAHALARVGEIAQEL---GKGKIVVMNLCGRGDK 393
Query: 427 DLKGYEDYLDGKL 439
D+ + L K+
Sbjct: 394 DIFTVAEALGRKI 406
>dbj|BAB05382.1| (AP001512) tryptophan synthase (beta subunit) [Bacillus halodurans]
Length = 399
Score = 148 bits (371), Expect = 9e-35
Identities = 121/361 (33%), Positives = 170/361 (46%), Gaps = 49/361 (13%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPT L A N+ + LG A+IY K E TG+HK+N A+ QA AK+ G +++V ETG
Sbjct: 57 GRPTALTYAKNMSETLGG-AKIYLKREDLLHTGAHKLNNAMGQALLAKRMGKKKIVAETG 115
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A + A GL+ +V+M +++ M + GAEV P+ S G + L
Sbjct: 116 AGQHGVATATIAARFGLECKVFMGEEDMERQALNVFRMELLGAEVVPATS-----GSKTL 170
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQM 258
K+ A +EAI V + Y +GSV+ V Q +IG EA+ Q
Sbjct: 171 KD----------ATNEAIRYWVTHADDTFYLIGSVVGPHPYPQMVRDFQRIIGDEARAQF 220
Query: 259 EEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVL---------DGKSEYEFIAVEPKAAPT 307
+E P +I CVGGGSN G YPF++D + G + A K
Sbjct: 221 QEITGTLPTEVIACVGGGSNAIGTFYPFLEDDVKLIGVEAAGKGVETSQHAATITKGRVG 280
Query: 308 MTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPI 367
+ G TY D AG + P + GL Y G+ P + L + G VK
Sbjct: 281 VIHGSMTYLLQDDAGQITE------------PYSISAGLDYPGVGPEHAYLASTGRVKYD 328
Query: 368 AYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLD 427
A E +A + EGI+PA ESAHA+ ++ A++ +E IL LSG G D
Sbjct: 329 AVTDKEALDALKQLSVHEGIIPAVESAHALAKAFER---AKQLSQEESILVCLSGRGDKD 385
Query: 428 L 428
+
Sbjct: 386 V 386
>sp|P16706|TRPB_ACICA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|95335|pir||B36151 tryptophan
synthase (EC 4.2.1.20) beta chain - Acinetobacter
calcoaceticus >gi|141798|gb|AAA21902.1| (M58444)
tryptophan synthase beta-subunit [Acinetobacter
calcoaceticus]
Length = 403
Score = 147 bits (368), Expect = 2e-34
Identities = 122/369 (33%), Positives = 177/369 (47%), Gaps = 50/369 (13%)
Query: 79 RKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIE 138
R L +GRP+PL+ A K LG A+IY K E TGSHK+N + QA AK G +
Sbjct: 52 RDLAYYVGRPSPLYYAERWSKKLGG-AQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKK 110
Query: 139 RLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENT 198
R++ ETGAGQ G A + A LGL+ V+M +++ MR+ GA V P S
Sbjct: 111 RIIAETGAGQHGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGATVIPVQS--- 167
Query: 199 EVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIG 251
G + LK+ A++EA+ D V + Y +G+V V Q++IG
Sbjct: 168 --GSKTLKD----------AMNEAMRDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIG 215
Query: 252 LEAKEQMEE--FEEPDVIIGCVGGGSNFAGLAYPFVKD----VLDGKSEYEFIAVEPKAA 305
EA+ Q++E PD ++ CVGGGSN GL YPF+ D + ++ I +A
Sbjct: 216 REARRQIQEQAGRLPDALVACVGGGSNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSA 275
Query: 306 PT------MTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
P + G TY D G ++ H++ + GL Y G+ P S L
Sbjct: 276 PLNAGHVGVLHGNRTYLMSDPQGQI--IETHSI----------SAGLDYPGVGPEHSFLK 323
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFN 419
+ V+ + E + + EGI+PA ESAHA+ A + K A K+ +I+ N
Sbjct: 324 DMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHAM-AYVTKL--APTMDKDQIIIAN 380
Query: 420 LSGHGLLDL 428
+SG G DL
Sbjct: 381 VSGRGDKDL 389
>pir||T07937 tryptophan synthase (EC 4.2.1.20) beta chain - Chlamydomonas
reinhardtii (fragment) >gi|2970343|gb|AAC25986.1|
(AF047024) tryptophan synthase beta [Chlamydomonas
reinhardtii]
Length = 444
Score = 147 bits (367), Expect = 3e-34
Identities = 124/375 (33%), Positives = 168/375 (44%), Gaps = 53/375 (14%)
Query: 85 IGRPTPLFRATNLEKLLGTP----ARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+GR TPL+ A L T A IY K E TG+HKIN +L QA K+ +R+
Sbjct: 99 VGRETPLYHAERLSAHYKTADGGHAEIYLKREDLNHTGAHKINNSLGQALLCKRLNKQRI 158
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A LGLK VYM +++ MR+ GAEV P S
Sbjct: 159 IAETGAGQHGVATATICARLGLKCIVYMGAKDMERQALNVFRMRLCGAEVRPVNS----- 213
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLE 253
G LK+ A SEAI D V E Y LGS V Q+VIG E
Sbjct: 214 GTATLKD----------ATSEAIRDWVTNVETTHYILGSAAGPHPYPMMVREFQSVIGRE 263
Query: 254 AKEQMEE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVL----------DGKSEYEFIAVE 301
K Q +E PD+++ CVGGGSN G+ F+ D +G + + A
Sbjct: 264 TKVQAQEKWGGLPDIVMACVGGGSNAIGIFNEFINDTSVRLIGVEAGGEGVNTTKHAATL 323
Query: 302 PKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINH 361
P + G Y+Y D G + P + GL Y G+ P S L +
Sbjct: 324 TMGTPGVLHGSYSYLLQDDDG------------QIIDPHSISAGLDYPGIGPEHSFLKDV 371
Query: 362 GIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLS 421
+ A E E L +K EGI+PA E++HA+ A ++K + + G +VI N S
Sbjct: 372 KRAEYYAVTDAEALEGFQLLSKLEGIIPALETSHAI-AYLEKLIPTLKSGTRVVI--NCS 428
Query: 422 GHGLLDLKGYEDYLD 436
G G D+ Y++
Sbjct: 429 GRGDKDVNNAMKYIN 443
>sp|Q59169|TRPB_BUCSC TRYPTOPHAN SYNTHASE BETA CHAIN >gi|769838|gb|AAA92796.1| (U09185)
tryptophan synthase beta subunit [Buchnera aphidicola]
Length = 392
Score = 146 bits (366), Expect = 3e-34
Identities = 123/369 (33%), Positives = 173/369 (46%), Gaps = 48/369 (13%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL NL K GT RIY K E G+HK N L QA AK+ + ++ ETG
Sbjct: 53 GRPTPLTLCRNLTK--GTNTRIYLKREDLLHGGAHKTNQVLGQALLAKQMKKKEIIAETG 110
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A +L+ ALL LK R+YM +++ M++ GA+V P S N
Sbjct: 111 AGQHGVAAALSCALLNLKCRIYMGIKDIERQKQNVFRMKLMGAQVIPVKSGN-------- 162
Query: 206 KEDPNHPGSLGIAISEAIEDVLKDE-KARYSLGSVLNH------VLMHQTVIGLEAKEQM 258
G+L A +EA+ D ++ A Y LG+ V Q+VIG E K+Q+
Sbjct: 163 -------GTLKDACNEALRDWSENYINAHYMLGTAAGPHPYPTIVKQFQSVIGKETKQQI 215
Query: 259 EEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
E E P+ +I CVGGGSN G+ F++D + I VEP G++T
Sbjct: 216 FEKEHCLPNSVIACVGGGSNAIGIFSSFIED-----TSVNLIGVEPGGI-----GIHTEK 265
Query: 317 YGDSA---------GLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPI 367
+G S G+ K+ G I A GL + + P + L + V +
Sbjct: 266 HGASLICGETGIFFGMKSKVMQTHEGQIKESWSISA-GLDFPAVGPEHAWLDSIKRVTYV 324
Query: 368 AYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLD 427
+ +E A +K EGI+PA ES+HA+ I L K ++ N+SG G D
Sbjct: 325 SITDSEAVHAFQHLSKLEGIIPALESSHALAYAI--KLMNNYPNKNQTLIVNISGRGDKD 382
Query: 428 LKGYEDYLD 436
LK E +L+
Sbjct: 383 LKTVEKFLN 391
>sp|P14671|TRP1_ARATH TRYPTOPHAN SYNTHASE BETA CHAIN 1 PRECURSOR >gi|99767|pir||A31393
tryptophan synthase (EC 4.2.1.20) beta-1 chain precursor
- Arabidopsis thaliana >gi|166892|gb|AAA32878.1|
(M23872) tryptophan synthase beta subunit [Arabidopsis
thaliana] >gi|9758261|dbj|BAB08760.1| (AB005232)
tryptophan synthase beta chain 1 precursor [Arabidopsis
thaliana]
Length = 470
Score = 145 bits (361), Expect = 1e-33
Identities = 127/373 (34%), Positives = 173/373 (46%), Gaps = 49/373 (13%)
Query: 85 IGRPTPLFRATNLEKLL----GTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+GR +PL+ A L + G IY K E TG+HKIN A+AQA AK+ G +R+
Sbjct: 125 VGRESPLYFAERLTEHYRRENGEGPLIYLKREDLNHTGAHKINNAVAQALLAKRLGKKRI 184
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A GL+ +YM +++ MR+ GAEV
Sbjct: 185 IAETGAGQHGVATATVCARFGLECIIYMGAQDMERQALNVFRMRLLGAEV-----RGVHS 239
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLE 253
G LK+ A SEAI D V E Y LGSV V VIG E
Sbjct: 240 GTATLKD----------ATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGKE 289
Query: 254 AKEQMEE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------K 303
++Q E +PDV++ CVGGGSN GL + FV D +E I VE K
Sbjct: 290 TRKQALEKWGGKPDVLVACVGGGSNAMGLFHEFVND-----TEVRMIGVEAAGFGLDSGK 344
Query: 304 AAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGI 363
A T+T+G D G G L G + P + GL Y G+ P S + G
Sbjct: 345 HAATLTKG----DVGVLHGAMSYLLQDDDG-QIIEPHSISAGLDYPGVGPEHSFFKDMGR 399
Query: 364 VKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGH 423
+ + E EA ++ EGI+PA E++HA+ A ++K +G +V+ N SG
Sbjct: 400 AEYYSITDEEALEAFKRVSRLEGIIPALETSHAL-AYLEKLCPTLSDGTRVVL--NFSGR 456
Query: 424 GLLDLKGYEDYLD 436
G D++ YLD
Sbjct: 457 GDKDVQTVAKYLD 469
>gb|AAD51338.1|AF173835_2 (AF173835) tryptophan synthetase beta subunit [Zymomonas mobilis
subsp. pomaceae]
Length = 408
Score = 144 bits (359), Expect = 2e-33
Identities = 130/400 (32%), Positives = 191/400 (47%), Gaps = 46/400 (11%)
Query: 42 PETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLL 101
PET PI +E L + + L ER +L + Y +GRP+PL+ A L +
Sbjct: 31 PETLMPIILE-LNQEYRRALKDPSFIAER-----DDLLEHY--VGRPSPLYFAPRLTEAW 82
Query: 102 GTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLG 161
G A+IY K E TG+HKIN + Q AK+ G R++ ETGAGQ G A + A G
Sbjct: 83 GG-AKIYLKREDLNHTGAHKINNCIGQVLLAKRMGKTRVIAETGAGQHGVATATVAARFG 141
Query: 162 LKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISE 221
L V+M +++ M++ GAEV P + G R LK+ A++E
Sbjct: 142 LSCTVFMGELDTERQQPNVFRMKLLGAEVRP-----VKAGSRTLKD----------AMNE 186
Query: 222 AIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQMEEFEE--PDVIIGCVG 272
A+ D V + Y LG+ V Q+VIG EA+EQ+++ E+ PD++I +G
Sbjct: 187 ALRDWVAHIDDTFYILGTAAGPHPYPEMVRDFQSVIGREAREQIQKAEKRLPDLLIARLG 246
Query: 273 GGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDY-GDSAGLTPKLKMHT 331
GGSN GL +PF+ D ++ I VE A M G + G + G+ + +
Sbjct: 247 GGSNAMGLFHPFLDD-----TDVAMIGVE-AAGEGMETGRHAASLTGGAPGIVHGNRTYL 300
Query: 332 L-GHRYYVPPIH--AGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIV 388
L + H + GL Y G+ P S L + V+ E A + EGI+
Sbjct: 301 LYDENGQIKDAHSISAGLDYPGIGPEHSWLKDIKRVRYETITDNEALAAFQQLCRLEGII 360
Query: 389 PAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
PA ES+H A+ + A A GK+ +I+ NLSG G D+
Sbjct: 361 PALESSH---ALAEAAKIAPTMGKDKIIIVNLSGRGDKDI 397
>sp|P00933|TRPB_SALTY TRYPTOPHAN SYNTHASE BETA CHAIN >gi|4699724|pdb|1BKS|B Chain B,
Tryptophan Synthase (E.C.4.2.1.20) From Salmonella
Typhimurium >gi|1421255|pdb|1TTQ|B Chain B, Tryptophan
Synthase (E.C.4.2.1.20) In The Presence Of Potassium At
Room Temperature >gi|1421253|pdb|1TTP|B Chain B,
Tryptophan Synthase (E.C.4.2.1.20) In The Presence Of
Cesium, Room Temperature >gi|6730204|pdb|1CW2|B Chain B,
Crystal Structure Of The Complex Of Bacterial Tryptophan
Synthase With The Transition State Analogue Inhibitor
4-(2- Hydroxyphenylsulfinyl)-Butylphosphonic Acid
>gi|6980601|pdb|1C8V|B Chain B, Crystal Structure Of The
Complex Of Bacterial Tryptophan Synthase With The
Transition State Analogue Inhibitor 4-(2-
Hydroxyphenylthio)-Butylphosphonic Acid
>gi|4699591|pdb|1A5S|B Chain B, Crystal Structure Of
Wild-Type Tryptophan Synthase Complexed With
5-Fluoroindole Propanol Phosphate And L-Ser Bound As
Amino Acrylate To The Beta Site >gi|6980565|pdb|1C29|B
Chain B, Crystal Structure Of The Complex Of Bacterial
Tryptophan Synthase With The Transition State Analogue
Inhibitor 4-(2- Hydroxyphenylthio)-1-Butenylphosphonic
Acid >gi|6730160|pdb|1C9D|B Chain B, Crystal Structure
Of The Complex Of Bacterial Tryptophan Synthase With The
Transition State Analogue Inhibitor 4-(2-
Hydroxy-4-Fluorophenylthio)-Butylphosphonic Acid
>gi|6730207|pdb|1CX9|B Chain B, Crystal Structure Of The
Complex Of Bacterial Tryptophan Synthase With The
Transition State Analogue Inhibitor 4-(2-
Aminophenylthio)-Butylphosphonic Acid
>gi|47942|emb|CAA24667.1| (V01377) reading frame (trpB)
[Salmonella typhimurium] >gi|154385|gb|AAA27234.1|
(J01810) trpb [Salmonella typhimurium]
Length = 397
Score = 143 bits (358), Expect = 3e-33
Identities = 128/383 (33%), Positives = 176/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ +E PD +I CVGGGSN G+ F+ D G I VEP
Sbjct: 208 IGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE--GKEMVIL 417
+ G ++ E EA + EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 SIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHA----LAHALKMMREQPEKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>pir||TSEBBT tryptophan synthase (EC 4.2.1.20) beta chain - Salmonella
typhimurium >gi|4699588|pdb|1A50|B Chain B, Crystal
Structure Of Wild-Type Tryptophan Synthase Complexed
With 5-Fluoroindole Propanol Phosphate
>gi|4699620|pdb|2WSY|B Chain B, Crystal Structure Of
Wild-Type Tryptophan Synthase
Length = 396
Score = 143 bits (358), Expect = 3e-33
Identities = 128/383 (33%), Positives = 176/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 46 DLLKNYA--GRPTALTKCQNITA--GTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 101
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 102 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 160
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 161 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 206
Query: 250 IGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ +E PD +I CVGGGSN G+ F+ D G I VEP
Sbjct: 207 IGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG-----LIGVEPGG--- 258
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 259 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLN 316
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE--GKEMVIL 417
+ G ++ E EA + EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 317 SIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHA----LAHALKMMREQPEKEQLLV 372
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 373 VNLSGRGDKDIFTVHDILKARGE 395
>sp|P13228|TRP_NEUCR TRYPTOPHAN SYNTHASE >gi|101877|pir||A32959 tryptophan synthase (EC
4.2.1.20) - Neurospora crassa >gi|168916|gb|AAA33616.1|
(J04594) tryptophan synthetase [Neurospora crassa]
Length = 708
Score = 143 bits (358), Expect = 3e-33
Identities = 118/379 (31%), Positives = 183/379 (48%), Gaps = 52/379 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
E R Y +GRP L +A L + G A I+ K E TGSHKIN AL Q A++ G
Sbjct: 349 EYRSYYPWMGRPGQLHKAERLTEYAGG-ANIWLKREDLNHTGSHKINNALGQLLLARRLG 407
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++++ ETGAGQ G A + A G++ V+M +++ M++ GA+V
Sbjct: 408 KKKIIAETGAGQHGVATATVCAKFGMECTVFMGAEDVRRQALNVFRMKLLGAKVVA---- 463
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTV 249
E G R L++ A++EA+ V+ Y +GS + V Q+V
Sbjct: 464 -VEAGSRTLRD----------AVNEALRYWVVNLADTHYIIGSAIGPHPFPTIVRTFQSV 512
Query: 250 IGLEAKEQMEE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE------ 301
IG E K+QM E + PD ++ CVGGGSN G+ YPF D + + VE
Sbjct: 513 IGNETKQQMLEKRGKLPDAVVACVGGGSNAVGMFYPFSND-----PSVKLLGVEAGGDGV 567
Query: 302 --PKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRY-YVPPIH--AGGLRYHGLAPTLS 356
P+ + T+T G S G+ ++ + L ++Y + H + GL Y G+ P LS
Sbjct: 568 DTPRHSATLTAG--------SKGVLHGVRTYILQNQYGQIEDTHSISAGLDYPGVGPELS 619
Query: 357 VLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVI 416
+ K +A + FE L ++ EGI+PA ES+H + ++ A + + +++VI
Sbjct: 620 NWKDTERAKFVAATDAQAFEGFRLMSQLEGIIPALESSHGIWGALELA-KTMKPDEDVVI 678
Query: 417 LFNLSGHGLLDLKGYEDYL 435
LSG G D++ D L
Sbjct: 679 C--LSGRGDKDVQSVADEL 695
>sp|P25269|TRP2_ARATH TRYPTOPHAN SYNTHASE BETA CHAIN 2 PRECURSOR >gi|7437013|pir||T06037
tryptophan synthase (EC 4.2.1.20) beta chain T24A18.20 -
Arabidopsis thaliana >gi|166894|gb|AAA32879.1| (M81620)
tryptophan synthase beta-subunit [Arabidopsis thaliana]
>gi|4490703|emb|CAB38837.1| (AL035680) tryptophan
synthase beta-subunit (TSB2) [Arabidopsis thaliana]
>gi|7269560|emb|CAB79562.1| (AL161566) tryptophan
synthase beta-subunit (TSB2) [Arabidopsis thaliana]
Length = 475
Score = 143 bits (358), Expect = 3e-33
Identities = 135/408 (33%), Positives = 190/408 (46%), Gaps = 56/408 (13%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLL----GTPA 105
+ +L+ F ++ RE E+ K Y +GR +PL+ A L + G
Sbjct: 102 LSELETAFYSLATDEDFQREL-----AEILKDY--VGRESPLYFAERLTEHYRRENGEGP 154
Query: 106 RIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVR 165
IY K E TG+HKIN A+AQA AK+ G +R++ ETGAGQ G A + A GL+
Sbjct: 155 LIYLKREDLNHTGAHKINNAVAQALLAKRLGKKRIIAETGAGQHGVATATVCARFGLQCI 214
Query: 166 VYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED 225
+YM +++ MR+ GAEV G LK+ A SEAI D
Sbjct: 215 IYMGAQDMERQALNVFRMRLLGAEV-----RGVHSGTATLKD----------ATSEAIRD 259
Query: 226 -VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQ-MEEF-EEPDVIIGCVGGGSN 276
V E Y LGSV V VIG E ++Q ME++ +PDV++ CVGGGSN
Sbjct: 260 WVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGKETRKQAMEKWGGKPDVLVACVGGGSN 319
Query: 277 FAGLAYPFVKDVLDGKSEYEFIAVEP--------KAAPTMTRGVYTYDYGDSAGLTPKLK 328
GL + FV D +E I VE K A T+T+G D G G L
Sbjct: 320 AMGLFHEFVDD-----TEVRMIGVEAAGFGLDSGKHAATLTKG----DVGVLHGAMSYLL 370
Query: 329 MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIV 388
G + P + GL Y G+ P S L + G + + E EA ++ EGI+
Sbjct: 371 QDDDG-QIIEPHSISAGLDYPGVGPEHSFLKDVGRAEYFSVTDEEALEAFKRVSRLEGII 429
Query: 389 PAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLD 436
PA E++HA+ A ++K +G +V+ N SG G D++ YL+
Sbjct: 430 PALETSHAL-AHLEKLCPTLPDGARVVL--NFSGRGDKDVQTAIKYLE 474
>pdb|1QOP|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With Indole Propanol Phosphate
Length = 396
Score = 143 bits (358), Expect = 3e-33
Identities = 128/383 (33%), Positives = 176/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 46 DLLKNYA--GRPTALTKCQNITA--GTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 101
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 102 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 160
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 161 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 206
Query: 250 IGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ +E PD +I CVGGGSN G+ F+ D G I VEP
Sbjct: 207 IGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG-----LIGVEPGG--- 258
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 259 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLN 316
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE--GKEMVIL 417
+ G ++ E EA + EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 317 SIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHA----LAHALKMMREQPEKEQLLV 372
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 373 VNLSGRGDKDIFTVHDILKARGE 395
>pir||JN0593 tryptophan synthase (EC 4.2.1.20) beta chain - Bacillus
amyloliquefaciens >gi|216357|dbj|BAA03153.1| (D14069)
tryptophan synthase B [Bacillus subtilis]
>gi|448381|prf||1917173A Trp synthase:SUBUNIT=beta
[Bacillus subtilis]
Length = 400
Score = 143 bits (357), Expect = 4e-33
Identities = 126/380 (33%), Positives = 175/380 (45%), Gaps = 49/380 (12%)
Query: 81 LYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
L+ GRPT L A + LG A+IY K E TGSHKIN AL Q AKK G ++
Sbjct: 51 LFDYSGRPTALTFADRVSDDLGG-AKIYLKREDLNHTGSHKINNALGQILLAKKMGKTKI 109
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A A G + V+M ++ M++ GAEV P S N
Sbjct: 110 IAETGAGQHGVAAATAAAKFGFECTVFMGEEDVARQSLNVFRMKLLGAEVVPVSSGN--- 166
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIGLE 253
G+L A +EAI V E Y +GSV+ V Q +IG E
Sbjct: 167 ------------GTLKDATNEAIRYWVQHCEDHFYLIGSVVGPHPYPYIVREFQKIIGEE 214
Query: 254 AKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE--------PK 303
AKEQ+ E PD ++ CVGGG+N G+ F+ + + E I VE P
Sbjct: 215 AKEQLLRVEGTLPDKVVACVGGGTNAMGIFQAFLDE------DTELIGVEAAGKGIDTPL 268
Query: 304 AAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGI 363
A T+ +G +G L + + P + GL Y G+ P + L G
Sbjct: 269 HAATIAKGTLGVIHGSMTYL-----IQDAYGQIIEPYSISAGLDYPGIGPEHAYLHKSGR 323
Query: 364 VKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALE-ARREGKEMVILFNLSG 422
V + E A L ++ EGI+PA ESAHA + KA E A+ K+ +IL +LSG
Sbjct: 324 VTYESVTDEEAIAALRLLSETEGILPAIESAHA----LAKAFEMAKDMDKDKIILVSLSG 379
Query: 423 HGLLDLKGYEDYLDGKLEDY 442
G D+ + L+ ++ +
Sbjct: 380 RGDKDVHTLMNVLENAVKTH 399
>sp|O05625|TRPB_STRCO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7481832|pir||T35066 tryptophan
synthase beta chain - Streptomyces coelicolor
>gi|3169557|gb|AAC63502.1| (AF054585) tryptophan
synthase beta subunit [Streptomyces coelicolor A3(2)]
>gi|5596782|emb|CAB51429.1| (AL096884) tryptophan
synthase beta subunit [Streptomyces coelicolor A3(2)]
Length = 427
Score = 143 bits (357), Expect = 4e-33
Identities = 126/363 (34%), Positives = 168/363 (45%), Gaps = 52/363 (14%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRP+ L G ARI+ K E TGSHKIN L QA K+ G R++ ETG
Sbjct: 66 GRPSALTEVPRFAAEAGG-ARIFLKREDLNHTGSHKINNVLGQALLTKRMGKTRVIAETG 124
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A + A AL GL +YM +++ MR+ GAEV S G R L
Sbjct: 125 AGQHGVATATACALFGLDCTIYMGEIDTRRQALNVARMRMLGAEVIAVKS-----GSRTL 179
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQM 258
K+ AI+EA D V ++ Y G+V V VIG+EA+ Q+
Sbjct: 180 KD----------AINEAFRDWVANVDRTHYLFGTVAGPHPFPAMVRDFHRVIGVEARRQL 229
Query: 259 EE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
E PD I CVGGGSN GL + F+ D ++ I EP GV T +
Sbjct: 230 LEQAGRLPDAAIACVGGGSNAIGLFHAFIPD-----ADVRLIGCEPAG-----HGVETGE 279
Query: 317 YGDSAGLTPKLKMHTLGHRYYV----------PPIHAGGLRYHGLAPTLSVLINHGIVKP 366
+ +A LT G R YV P + GL Y G+ P + L + G +
Sbjct: 280 H--AATLTAGEPGILHGSRSYVLQDDEGQITEPYSISAGLDYPGIGPEHAYLKDSGRGEY 337
Query: 367 IAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE-GKEMVILFNLSGHGL 425
A +A L ++ EGI+PA ESAHA+ ALE RE G++ +++ NLSG G
Sbjct: 338 RAVTDDAAMQALRLLSRTEGIIPAIESAHALAG----ALEVGRELGRDGLLVVNLSGRGD 393
Query: 426 LDL 428
D+
Sbjct: 394 KDM 396
>pdb|1BEU|B Chain B, Trp Synthase (D60n-Ipp-Ser) With K+ >gi|3212366|pdb|1A5A|B
Chain B, Cryo-Crystallography Of A True Substrate,
Indole-3-Glycerol Phosphate, Bound To A Mutant
(Alphad60n) Tryptophan Synthase Alpha2beta2 Complex
Reveals The Correct Orientation Of Active Site Alpha Glu
49 >gi|3212368|pdb|1A5B|B Chain B, Cryo-Crystallography
Of A True Substrate, Indole-3-Glycerol Phosphate, Bound
To A Mutant (Alpha D60n) Tryptophan Synthase Alpha2beta2
Complex Reveals The Correct Orientation Of Active Site
Alpha Glu 49
Length = 397
Score = 143 bits (357), Expect = 4e-33
Identities = 127/381 (33%), Positives = 175/381 (45%), Gaps = 52/381 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ +E PD +I CVGGGSN G+ F+ D G I VEP
Sbjct: 208 IGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE--GKEMVIL 417
+ G ++ E EA + EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 SIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHA----LAHALKMMREQPEKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGK 438
NLSG G D+ D L +
Sbjct: 374 VNLSGRGDKDIFTVHDILKAR 394
>pdb|1QOQ|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With Indole Glycerol Phosphate
Length = 396
Score = 143 bits (357), Expect = 4e-33
Identities = 128/383 (33%), Positives = 176/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 46 DLLKNYA--GRPTALTKCQNITA--GTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 101
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 102 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 160
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 161 ----GSATLKD----------ACNEALADWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 206
Query: 250 IGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ +E PD +I CVGGGSN G+ F+ D G I VEP
Sbjct: 207 IGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG-----LIGVEPGG--- 258
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 259 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLN 316
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE--GKEMVIL 417
+ G ++ E EA + EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 317 SIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHA----LAHALKMMREQPEKEQLLV 372
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 373 VNLSGRGDKDIFTVHDILKARGE 395
>gb|AAC60450.1| (S65045) tryptophan synthase beta-subunit, TrpB [Bacillus subtilis,
K, Peptide, 400 aa]
Length = 400
Score = 143 bits (356), Expect = 5e-33
Identities = 126/380 (33%), Positives = 175/380 (45%), Gaps = 49/380 (12%)
Query: 81 LYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
L+ GRPT L A + LG A+IY K E TGSHKIN AL Q AKK G ++
Sbjct: 51 LFDYSGRPTALTFADRVSDDLGG-AKIYLKREDLNHTGSHKINNALGQILLAKKMGKTKI 109
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A A G + V+M ++ M++ GAEV P S N
Sbjct: 110 IAETGAGQHGVAAATAAAKFGFECTVFMGEEDVARQSLNVFRMKLLGAEVVPVSSGN--- 166
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIGLE 253
G+L A +EAI V E Y +GSV+ V Q +IG E
Sbjct: 167 ------------GTLKDATNEAIRYWVQHCEDHFYLIGSVVGPHPYPYIVREFQKIIGEE 214
Query: 254 AKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE--------PK 303
AKEQ+ E PD ++ CVGGG+N G+ F+ + + E I VE P
Sbjct: 215 AKEQLLRVEGTLPDKVVACVGGGTNAMGIFQAFLDE------DTELIGVEAAGKGIDTPL 268
Query: 304 AAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGI 363
A T+ +G +G L + + P + GL Y G+ P + L G
Sbjct: 269 HAATIAKGTLGVIHGSMTYL-----IQDAYGQIIEPYSISAGLDYPGIGPEHAYLHKSGR 323
Query: 364 VKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALE-ARREGKEMVILFNLSG 422
V + E A L ++ EGI+PA ESAHA + KA E A+ K+ +IL +LSG
Sbjct: 324 VTYESVTDEEALAALRLLSETEGILPAIESAHA----LAKAFEMAKDMDKDKIILVSLSG 379
Query: 423 HGLLDLKGYEDYLDGKLEDY 442
G D+ + L+ ++ +
Sbjct: 380 RGDKDVHTLMNVLENGVKTH 399
>gb|AAF91181.1|AF207903_2 (AF207903) bifunctional tryptophan synthase TRPB [Aspergillus
nidulans]
Length = 723
Score = 142 bits (355), Expect = 7e-33
Identities = 117/378 (30%), Positives = 172/378 (44%), Gaps = 50/378 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
E R Y +GRP+ L AT L + +G A I+ K E TGSHKIN AL Q A++ G
Sbjct: 364 EYRSYYPYMGRPSSLHLATRLTEHVGG-ANIWLKREDLNHTGSHKINNALGQILLARRLG 422
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
R++ ETGAGQ G A + A G+K VYM +++ M++ GA V
Sbjct: 423 KTRIIAETGAGQHGVATATVCAKFGMKCVVYMGAEDVRRQALNVFRMKLLGASVVA---- 478
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
+ G R L++ A++EA+ + D + Y +GS + V +Q+V
Sbjct: 479 -VDAGSRTLRD----------AVNEALRAWVVDLDTTHYIIGSAIGPHPFPTIVRTYQSV 527
Query: 250 IGLEAKEQMEE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVL----------DGKSEYEF 297
IG E K+Q++E + PD ++ CVGGGSN G YPF KD DG
Sbjct: 528 IGEETKQQLQEQIGKLPDAVVACVGGGSNAVGSFYPFSKDTSVKLLGVEAGGDGIDTNRH 587
Query: 298 IAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSV 357
A + + GV TY D G + H++ + GL Y G+ P LS
Sbjct: 588 SATLSGGSKGVLHGVRTYILQDEHGQVS--ETHSI----------SAGLDYPGVGPELSN 635
Query: 358 LINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVIL 417
+ IA + A+ EGI+PA ES+HA+ + A + +G I+
Sbjct: 636 WKDSDRAHFIAATDAQALSGFRTMAQTEGIIPALESSHAIWGAQELAKTMKGKGD---IV 692
Query: 418 FNLSGHGLLDLKGYEDYL 435
+SG G D++ + L
Sbjct: 693 LTVSGRGDKDVESVAESL 710
>sp|Q9ZJU9|TRPB_HELPJ TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437012|pir||C71836 tryptophan
synthase beta chain - Helicobacter pylori (strain J99)
>gi|4155803|gb|AAD06778.1| (AE001546) TRYPTOPHAN
SYNTHASE BETA CHAIN [Helicobacter pylori J99]
Length = 393
Score = 142 bits (354), Expect = 9e-33
Identities = 128/413 (30%), Positives = 185/413 (43%), Gaps = 64/413 (15%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYF 109
+ +L++ F L +E +E + R L +GRP+PL N+ + ++Y
Sbjct: 23 LRELEQAFDTCLKDEEFQKEYF-------RLLKDFVGRPSPLTLCQNI--VSNPKVKLYL 73
Query: 110 KYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMA 169
K E G+HK N AL QA AKK G R++ ETGAGQ G A ++A ALL LK ++M
Sbjct: 74 KREDLIHGGAHKTNQALGQALLAKKMGKTRIIAETGAGQHGVATAIACALLNLKCVIFMG 133
Query: 170 RASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD 229
+++ MR+ GAEV G LK+ A++EA+ D
Sbjct: 134 GKDIKRQEMNVFRMRLLGAEV-----REVNSGSATLKD----------AVNEALRDWASS 178
Query: 230 EK-ARYSLGSVL------NHVLMHQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGL 280
K Y LG+ V Q +IG E K Q+ E E PD +I CVGGGSN G+
Sbjct: 179 YKDTHYLLGTSAGPHPYPTMVKTFQKMIGDEVKSQILEKENRLPDYVIACVGGGSNAIGI 238
Query: 281 AYPFVKDVLDGKSEYEFIAVEP--------KAAPTMTRGVYTYDYGDSAGLTPK-----L 327
F+ D E + I VEP K T+ +G +G+ L
Sbjct: 239 FSAFLND-----KEVKLIGVEPAGLGLETNKHGATLNKGRVGILHGNKTYLLQDDEGQIA 293
Query: 328 KMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGI 387
+ H++ + GL Y G+ P S L G + E EA L + EGI
Sbjct: 294 ESHSI----------SAGLDYPGVGPEHSYLKEIGRAVYESASDIEALEAFRLLCQKEGI 343
Query: 388 VPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLDGKLE 440
+PA ES+HA+ + A++ +E +I+ NLSG G DL + L G L+
Sbjct: 344 IPALESSHALAYALKL---AQKCAQEKIIVVNLSGRGDKDLSTVYNALKGGLK 393
>sp|P56142|TRPB_HELPY TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437003|pir||F64679 tryptophan
synthase (EC 4.2.1.20) beta chain - Helicobacter pylori
(strain 26695) >gi|2314445|gb|AAD08323.1| (AE000632)
tryptophan synthase, beta subunit (trpB) [Helicobacter
pylori 26695]
Length = 393
Score = 141 bits (353), Expect = 1e-32
Identities = 127/413 (30%), Positives = 183/413 (43%), Gaps = 64/413 (15%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYF 109
+ +L++ F L ++ +E + R L +GRP+PL N+ + ++Y
Sbjct: 23 LRELEQAFDACLKDEKFQKEYF-------RLLKDFVGRPSPLTLCQNI--VSNPKVKLYL 73
Query: 110 KYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMA 169
K E G+HK N AL QA AKK G R++ ETGAGQ G A ++A ALL LK V+M
Sbjct: 74 KREDLIHGGAHKTNQALGQALLAKKMGKTRIIAETGAGQHGVATAIACALLNLKCVVFMG 133
Query: 170 RASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD 229
+++ M + GAEV G LK+ A++EA+ D
Sbjct: 134 SKDIKRQEMNVFRMHLLGAEV-----REVNSGSATLKD----------AVNEALRDWASS 178
Query: 230 EK-ARYSLGSVL------NHVLMHQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGL 280
K Y LG+ V Q +IG E K Q+ E E PD +I CVGGGSN G+
Sbjct: 179 YKDTHYLLGTAAGPHPYPTMVKTFQKMIGDEVKSQILEKENRLPDYVIACVGGGSNAIGI 238
Query: 281 AYPFVKDVLDGKSEYEFIAVEP--------KAAPTMTRGVYTYDYGDSAGLTPK-----L 327
F+ D E + I VEP K T+ +G +G+ L
Sbjct: 239 FSAFLND-----KEVKLIGVEPAGLGLETNKHGATLNKGRVGILHGNKTYLLQDDEGQIA 293
Query: 328 KMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGI 387
+ H++ + GL Y G+ P S L G + E EA L + EGI
Sbjct: 294 ESHSI----------SAGLDYPGVGPEHSYLKESGRAVYESASDAEALEAFKLLCQKEGI 343
Query: 388 VPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLDGKLE 440
+PA ES+HA+ + A + +E +I+ NLSG G DL + L G L+
Sbjct: 344 IPALESSHALAYALKLAQKCE---EESIIVVNLSGRGDKDLSTVYNALKGGLK 393
>pir||T47190 tryptophan synthase (EC 4.2.1.20) beta chain [imported] -
Escherichia coli >gi|775160|gb|AAA65163.1| (U23494)
tryptophan synthase beta subunit [Escherichia coli]
Length = 397
Score = 141 bits (352), Expect = 2e-32
Identities = 127/383 (33%), Positives = 176/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTKTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + ++ I VEP
Sbjct: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-----TDVGLIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E EA EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 STGRADYVSITDEEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPEKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>pdb|2TYS|B Chain B, Crystal Structures Of Mutant (Betak87t) Tryptophan
Synthase Alpha2 Beta2 Complex With Ligands Bound To The
Active Sites Of The Alpha And Beta Subunits Reveal
Ligand-Induced Conformational Changes
Length = 397
Score = 141 bits (352), Expect = 2e-32
Identities = 127/383 (33%), Positives = 175/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+H N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTRTTLYLKREDLLHGGAHTTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ +E PD +I CVGGGSN G+ F+ D G I VEP
Sbjct: 208 IGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE--GKEMVIL 417
+ G ++ E EA + EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 SIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHA----LAHALKMMREQPEKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>pir||H83640 tryptophan synthase beta chain PA0036 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9945857|gb|AAG03426.1|AE004443_4 (AE004443)
tryptophan synthase beta chain [Pseudomonas aeruginosa]
Length = 402
Score = 141 bits (352), Expect = 2e-32
Identities = 113/367 (30%), Positives = 173/367 (46%), Gaps = 56/367 (15%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
+GRP+PL+ A L + G A+IY K E TG+HKIN + Q A++ G +R++ ET
Sbjct: 58 VGRPSPLYFAERLTEHCGG-AKIYLKREELNHTGAHKINNCIGQILLARRMGKKRIIAET 116
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAG G A + A GL+ +YM ++ M++ GAEV P +
Sbjct: 117 GAGMHGVATATVAARFGLQCVIYMGTTDIDRQQANVFRMKLLGAEVIPVTAGT------- 169
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQ 257
G+L A++EA+ D V + Y +G+V V Q VIG E +EQ
Sbjct: 170 --------GTLKDAMNEALRDWVTNVDSTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQ 221
Query: 258 MEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------KAAPT 307
+ E E PD ++ C+GGGSN GL +PF+ D + + + VE K A +
Sbjct: 222 LAEKEGRLPDSLVACIGGGSNAMGLFHPFLDD-----AGVQIVGVEAAGHGIDTGKHAAS 276
Query: 308 MTRGVYTYDYGDSAGLTPK-----LKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHG 362
+ GV +G+ L + H++ + GL Y G+ P + L + G
Sbjct: 277 LNGGVPGVLHGNRTFLLQDADGQIIDAHSI----------SAGLDYPGIGPEHAWLHDTG 326
Query: 363 IVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSG 422
V+ + E EA + EGI+PA ES+HA+ V +A KE +++ NLSG
Sbjct: 327 RVEYTSITDDEALEAFHTCCRLEGIIPALESSHALAEVFKRAPSL---PKEHIMVVNLSG 383
Query: 423 HGLLDLK 429
G D++
Sbjct: 384 RGDKDMQ 390
>sp|P00932|TRPB_ECOLI TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7428396|pir||TSECB tryptophan
synthase (EC 4.2.1.20) beta chain - Escherichia coli
>gi|43205|emb|CAA23674.1| (V00372) trpB [Escherichia
coli] >gi|147958|gb|AAA57300.1| (J01714) tryptophan
synthase beta subunit [Escherichia coli]
>gi|775125|gb|AAB60034.1| (U23489) tryptophan synthase
beta subunit [Escherichia coli]
>gi|775132|gb|AAA65139.1| (U23490) tryptophan synthase
beta subunit [Escherichia coli]
>gi|775146|gb|AAA65151.1| (U23492) tryptophan synthase
beta subunit [Escherichia coli]
>gi|775153|gb|AAA65157.1| (U23493) tryptophan synthase
beta subunit [Escherichia coli]
>gi|775197|gb|AAA65175.1| (U23500) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924763|gb|AAA73790.1| (U25417) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924770|gb|AAA73796.1| (U25418) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924777|gb|AAA73802.1| (U25419) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924798|gb|AAA73820.1| (U25422) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924805|gb|AAA73826.1| (U25423) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924819|gb|AAA73838.1| (U25426) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924826|gb|AAA73844.1| (U25427) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924833|gb|AAA73850.1| (U25428) tryptophan synthase
beta subunit [Escherichia coli]
>gi|924840|gb|AAA73856.1| (U25429) tryptophan synthase
beta subunit [Escherichia coli]
>gi|1787515|gb|AAC74343.1| (AE000224) tryptophan
synthase, beta protein [Escherichia coli K12]
>gi|4377530|emb|CAA23663.1| (V00365) trpB [Escherichia
coli]
Length = 397
Score = 141 bits (351), Expect = 2e-32
Identities = 128/383 (33%), Positives = 175/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E EA EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPDKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>gb|AAA65145.1| (U23491) tryptophan synthase beta subunit [Escherichia coli]
Length = 397
Score = 141 bits (351), Expect = 2e-32
Identities = 128/383 (33%), Positives = 175/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E EA EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPDKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>gb|AAB60040.1| (U23495) tryptophan synthase beta subunit [Escherichia coli]
>gi|775180|gb|AAB60045.1| (U23497) tryptophan synthase
beta subunit [Escherichia coli]
>gi|775187|gb|AAB60051.1| (U23498) tryptophan synthase
beta subunit [Escherichia coli]
>gi|775192|gb|AAB60055.1| (U23499) tryptophan synthase
beta subunit [Escherichia coli]
>gi|1185400|gb|AAA87793.1| (U25884) tryptophan synthase
beta subunit [Escherichia coli]
>gi|1185405|gb|AAA87797.1| (U25885) tryptophan synthase
beta subunit [Escherichia coli]
>gi|1185410|gb|AAA87801.1| (U25886) tryptophan synthase
beta subunit [Escherichia coli]
Length = 397
Score = 141 bits (351), Expect = 2e-32
Identities = 127/383 (33%), Positives = 176/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + ++ I VEP
Sbjct: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-----TDVGLIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E EA EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPEKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>pdb|1UBS|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) With A Mutation Of Lys
87 ->thr In The B Subunit And In The Presence Of Ligand
L-Serine >gi|2098384|pdb|2TRS|B Chain B, Crystal
Structures Of Mutant (Betak87t) Tryptophan Synthase
Alpha2 Beta2 Complex With Ligands Bound To The Active
Sites Of The Alpha And Beta Subunits Reveal
Ligand-Induced Conformational Changes
>gi|2098386|pdb|2TSY|B Chain B, Crystal Structures Of
Mutant (Betak87t) Tryptophan Synthase Alpha2 Beta2
Complex With Ligands Bound To The Active Sites Of The
Alpha And Beta Subunits Reveal Ligand-Induced
Conformational Changes
Length = 397
Score = 141 bits (351), Expect = 2e-32
Identities = 126/381 (33%), Positives = 174/381 (45%), Gaps = 52/381 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+H N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTRTTLYLKREDLLHGGAHTTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ +E PD +I CVGGGSN G+ F+ D G I VEP
Sbjct: 208 IGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARRE--GKEMVIL 417
+ G ++ E EA + EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 SIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHA----LAHALKMMREQPEKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGK 438
NLSG G D+ D L +
Sbjct: 374 VNLSGRGDKDIFTVHDILKAR 394
>dbj|BAA14793.1| (D90763) Tryptophan synthase b chain (EC 4.2.1.20). [Escherichia
coli]
Length = 396
Score = 141 bits (351), Expect = 2e-32
Identities = 128/383 (33%), Positives = 175/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 46 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 101
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 102 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 160
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 161 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 206
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 207 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPGG--- 258
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 259 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 316
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E EA EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 317 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPDKEQLLV 372
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 373 VNLSGRGDKDIFTVHDILKARGE 395
>pir||E82232 tryptophan synthase, beta chain VC1170 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655646|gb|AAF94329.1|
(AE004197) tryptophan synthase, beta subunit [Vibrio
cholerae]
Length = 396
Score = 141 bits (351), Expect = 2e-32
Identities = 120/371 (32%), Positives = 166/371 (44%), Gaps = 48/371 (12%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPT L N+ K GT ++Y K E G+HK N L QA AK+ G ++ ETG
Sbjct: 53 GRPTALTLTQNITK--GTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKHEIIAETG 110
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A +LA ALLGLK RVYM +++ MR+ GA V P S G L
Sbjct: 111 AGQHGVATALACALLGLKCRVYMGAKDVERQSPNVFRMRLMGATVIPVHS-----GSATL 165
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIGLEAKEQM 258
K+ A +EA+ D E A Y LG+ V Q +IG E K Q+
Sbjct: 166 KD----------ACNEALRDWSASYETAHYLLGTAAGPHPFPTIVREFQRIIGEETKNQI 215
Query: 259 --EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
E PD +I CVGGGSN G+ F+++ I +EP +G++T+
Sbjct: 216 LAREGRLPDAVIACVGGGSNAIGMFADFIEE-----ESVRLIGIEPAG-----KGIHTHQ 265
Query: 317 YGDSA---------GLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPI 367
+G G+ L G + A GL + + P + L G +
Sbjct: 266 HGAPLKHGKTGIFFGMKAPLMQDEHGQVEESYSVSA-GLDFPSVGPQHAYLNAIGRAEYE 324
Query: 368 AYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLD 427
+ E +A A+ EGI+PA ES+HA+ I A KE +++ NLSG G D
Sbjct: 325 SITDDEALDAFQALARNEGIIPALESSHALAHAIKMAY--AEPDKEQLLVVNLSGRGDKD 382
Query: 428 LKGYEDYLDGK 438
+ L+ K
Sbjct: 383 IFTVHKLLEDK 393
>gb|AAA73808.1| (U25420) tryptophan synthase beta subunit [Escherichia coli]
Length = 397
Score = 140 bits (350), Expect = 3e-32
Identities = 128/383 (33%), Positives = 175/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQXPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E EA EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPDKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>pir||TSPSBA tryptophan synthase (EC 4.2.1.20) beta chain - Pseudomonas
aeruginosa
Length = 401
Score = 140 bits (350), Expect = 3e-32
Identities = 113/367 (30%), Positives = 173/367 (46%), Gaps = 56/367 (15%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
+GRP+PL+ A L + G A+IY K E TG+HKIN + Q A++ G +R++ ET
Sbjct: 57 VGRPSPLYFAERLTEHCGG-AKIYLKREELNHTGAHKINNCIGQILLARRMGKKRIIAET 115
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAG G A + A GL+ +YM ++ M++ GAEV P +
Sbjct: 116 GAGMHGLATATVAARFGLQCVIYMGTTDIDRQQANVFRMKLLGAEVIPVTAGT------- 168
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQ 257
G+L A++EA+ D V + Y +G+V V Q VIG E +EQ
Sbjct: 169 --------GTLKDAMNEALRDWVTNVDSTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQ 220
Query: 258 MEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------KAAPT 307
+ E E PD ++ C+GGGSN GL +PF+ D + + + VE K A +
Sbjct: 221 LAEKEGRLPDSLVACIGGGSNAMGLFHPFLDD-----AGVQIVGVEAAGHGIDTGKHAAS 275
Query: 308 MTRGVYTYDYGDSAGLTPK-----LKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHG 362
+ GV +G+ L + H++ + GL Y G+ P + L + G
Sbjct: 276 LNGGVPGVLHGNRTFLLQDADGQIIDAHSI----------SAGLDYPGIGPEHAWLHDIG 325
Query: 363 IVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSG 422
V+ + E EA + EGI+PA ES+HA+ V +A KE +++ NLSG
Sbjct: 326 RVEYTSITDDEALEAFHTCCRLEGIIPALESSHALAEVFKRAPSL---PKEHIMVVNLSG 382
Query: 423 HGLLDLK 429
G D++
Sbjct: 383 RGDKDMQ 389
>sp|P07345|TRPB_PSEAE TRYPTOPHAN SYNTHASE BETA CHAIN >gi|151616|gb|AAA88462.1| (M15826)
tryptophan synthase beta subunit [Pseudomonas
aeruginosa]
Length = 402
Score = 140 bits (350), Expect = 3e-32
Identities = 113/367 (30%), Positives = 173/367 (46%), Gaps = 56/367 (15%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
+GRP+PL+ A L + G A+IY K E TG+HKIN + Q A++ G +R++ ET
Sbjct: 58 VGRPSPLYFAERLTEHCGG-AKIYLKREELNHTGAHKINNCIGQILLARRMGKKRIIAET 116
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAG G A + A GL+ +YM ++ M++ GAEV P +
Sbjct: 117 GAGMHGLATATVAARFGLQCVIYMGTTDIDRQQANVFRMKLLGAEVIPVTAGT------- 169
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQ 257
G+L A++EA+ D V + Y +G+V V Q VIG E +EQ
Sbjct: 170 --------GTLKDAMNEALRDWVTNVDSTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQ 221
Query: 258 MEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------KAAPT 307
+ E E PD ++ C+GGGSN GL +PF+ D + + + VE K A +
Sbjct: 222 LAEKEGRLPDSLVACIGGGSNAMGLFHPFLDD-----AGVQIVGVEAAGHGIDTGKHAAS 276
Query: 308 MTRGVYTYDYGDSAGLTPK-----LKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHG 362
+ GV +G+ L + H++ + GL Y G+ P + L + G
Sbjct: 277 LNGGVPGVLHGNRTFLLQDADGQIIDAHSI----------SAGLDYPGIGPEHAWLHDIG 326
Query: 363 IVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSG 422
V+ + E EA + EGI+PA ES+HA+ V +A KE +++ NLSG
Sbjct: 327 RVEYTSITDDEALEAFHTCCRLEGIIPALESSHALAEVFKRAPSL---PKEHIMVVNLSG 383
Query: 423 HGLLDLK 429
G D++
Sbjct: 384 RGDKDMQ 390
>sp|P34817|TRPB_PSESY TRYPTOPHAN SYNTHASE BETA CHAIN >gi|476480|pir||JQ2126 tryptophan
synthase (EC 4.2.1.20) beta chain - Pseudomonas syringae
>gi|151620|gb|AAA26014.1| (M95710) tryptophan synthase
beta subunit [Pseudomonas syringae]
Length = 408
Score = 140 bits (350), Expect = 3e-32
Identities = 116/367 (31%), Positives = 175/367 (47%), Gaps = 56/367 (15%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
+GRP+PL+ A L + G A+IY K E TG+HKIN + Q A++ G +R++ ET
Sbjct: 62 VGRPSPLYFAERLTEFCGG-AKIYLKREELNHTGAHKINNCIGQILLARRMGKKRIIAET 120
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAG G A + A GL+ +YM +++ M++ GAEV P +
Sbjct: 121 GAGMHGVATATVAARFGLQCVIYMGTTDIERQQANVFRMKLLGAEVIPVVAGT------- 173
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQ 257
G+L A++EA+ D V E Y +G+V V Q VIG E ++Q
Sbjct: 174 --------GTLKDAMNEALRDWVTNVEDTFYLIGTVAGPHPYPAMVRDFQAVIGKETRDQ 225
Query: 258 M--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------KAAPT 307
+ +E PD ++ C+GGGSN GL +PF LD KS E I VE K A +
Sbjct: 226 LQAQEGRLPDSLVACIGGGSNAMGLFHPF----LDDKS-VEIIGVEAAGHGIETGKHAAS 280
Query: 308 MTRGVYTYDYGDSAGLTPK-----LKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHG 362
+ GV +G+ L + H++ + GL Y G+ P + L + G
Sbjct: 281 LNGGVPGVLHGNRTFLLQDDDGQIIDAHSI----------SAGLDYPGIGPEHAWLHDIG 330
Query: 363 IVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSG 422
V+ + E +A + EGI+PA ESAHA+ V +A K+ +++ NLSG
Sbjct: 331 RVQYTSVTDDEALDAFHKCCRLEGIIPALESAHALAEVFKRAPTL---PKDHLMVVNLSG 387
Query: 423 HGLLDLK 429
G D++
Sbjct: 388 RGDKDMQ 394
>pir||JQ1073 tryptophan synthase (EC 4.2.1.20) beta-2 chain precursor -
Arabidopsis thaliana
Length = 475
Score = 140 bits (349), Expect = 3e-32
Identities = 127/373 (34%), Positives = 176/373 (47%), Gaps = 49/373 (13%)
Query: 85 IGRPTPLFRATNLEKLL----GTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+GR +PL+ A L + G IY K E TG+HKIN A+A A AK+ G +R+
Sbjct: 130 VGRESPLYFAERLTEHYRRENGEGPLIYLKREDLNHTGAHKINNAVACALLAKRLGKKRI 189
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A GL+ +YM +++ MR+ GAEV
Sbjct: 190 IAETGAGQHGVATATVCARFGLQCIIYMGAQDMERQALNVFRMRLLGAEV-----RGVHS 244
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLE 253
G LK+ A SEAI D V E Y LGSV V VIG E
Sbjct: 245 GTATLKD----------ATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGKE 294
Query: 254 AKEQ-MEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------K 303
++Q ME++ +PDV++ CVGGGSN GL + FV D +E I VE K
Sbjct: 295 TRKQAMEKWGGKPDVLVACVGGGSNAMGLFHEFVDD-----TEVRMIGVEAAGFGLDSGK 349
Query: 304 AAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGI 363
A T+T+G D G G L G + P + GL Y G+ P S L + G
Sbjct: 350 HAATLTKG----DVGVLHGAMSYLLQDDDG-QIIEPHSISAGLDYPGVGPEHSFLKDVGR 404
Query: 364 VKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGH 423
+ + E EA ++ EGI+PA E++HA+ A ++K +G +V+ N SG
Sbjct: 405 AEYFSVTDEEALEAFKRVSRLEGIIPALETSHAL-AHLEKLCPTLPDGARVVL--NFSGR 461
Query: 424 GLLDLKGYEDYLD 436
G D++ YL+
Sbjct: 462 GDKDVQTAIKYLE 474
>sp|P07600|TRPB_BACSU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80435|pir||E22794 tryptophan
synthase (EC 4.2.1.20) beta chain - Bacillus subtilis
>gi|143772|gb|AAA22869.1| (K01391) TrpB protein
[Bacillus subtilis] >gi|143812|gb|AAA20865.1| (M80245)
TrpB [Bacillus subtilis] >gi|2634682|emb|CAB14180.1|
(Z99115) tryptophan synthase (beta subunit) [Bacillus
subtilis] >gi|224467|prf||1106178C protein trpB
[Bacillus subtilis]
Length = 400
Score = 139 bits (348), Expect = 5e-32
Identities = 136/427 (31%), Positives = 195/427 (44%), Gaps = 66/427 (15%)
Query: 32 LPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPL 91
+PE L PLD +++ F +++ RE Y + L K YS GRPT L
Sbjct: 19 VPETLMQPLD----------EIQTAF-KQIKDDPAFREEYYK----LLKDYS--GRPTAL 61
Query: 92 FRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGT 151
A + + LG A+IY K E TGSHKIN AL QA AKK G +++ ETGAGQ G
Sbjct: 62 TYADRVTEYLGG-AKIYLKREDLNHTGSHKINNALGQALLAKKMGKTKIIAETGAGQHGV 120
Query: 152 ALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNH 211
A + A G V+M ++ M++ GAEV P S N
Sbjct: 121 APATVAAKFGFSCTVFMGEEDVARQSLNVFRMKLLGAEVVPVTSGN-------------- 166
Query: 212 PGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIGLEAKEQMEEFE-- 262
G+L A +EAI V E Y +GSV+ V Q +IG EAK+Q++ E
Sbjct: 167 -GTLKDATNEAIRYWVQHCEDHFYMIGSVVGPHPYPQVVREFQKMIGEEAKDQLKRIEGT 225
Query: 263 EPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE--------PKAAPTMTRGVYT 314
PD ++ CVGGGSN G+ F+ + + E I E P A T+++G
Sbjct: 226 MPDKVVACVGGGSNAMGMFQAFLNE------DVELIGAEAAGKGIDTPLHAATISKGTVG 279
Query: 315 YDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEV 374
+G L + + P + GL Y G+ P + L G V + E
Sbjct: 280 VIHGSLTYL-----IQDEFGQIIEPYSISAGLDYPGIGPEHAYLHKSGRVTYDSITDEEA 334
Query: 375 FEAAVLFAKAEGIVPAPESAHAVKAVIDKALE-ARREGKEMVILFNLSGHGLLDLKGYED 433
+A L ++ EGI+PA ESAHA + KA + A+ + +IL LSG G D+ +
Sbjct: 335 VDALKLLSEKEGILPAIESAHA----LAKAFKLAKGMDRGQLILVCLSGRGDKDVNTLMN 390
Query: 434 YLDGKLE 440
L+ +++
Sbjct: 391 VLEEEVK 397
>sp|P17167|TRPB_LACCA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80566|pir||JS0343 tryptophan
synthase (EC 4.2.1.20) beta chain - Lactobacillus casei
>gi|216759|dbj|BAA00386.1| (D00496) trpB protein
[Lactobacillus casei]
Length = 406
Score = 139 bits (347), Expect = 6e-32
Identities = 115/368 (31%), Positives = 178/368 (48%), Gaps = 40/368 (10%)
Query: 81 LYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
L + RP+ L+ A N+ + LG A+IY K E TG+HKIN + QA AK G +RL
Sbjct: 58 LVNYANRPSLLYYAKNMTEDLGG-AKIYLKREDLNHTGAHKINNVIGQALLAKHLGKKRL 116
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + AL+G+ ++M + ++ M + GA+V P S
Sbjct: 117 IAETGAGQHGVATATIAALMGMDCEIFMGKEDTDRQKLNVYRMELLGAKVHPVTS----- 171
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN-----HVLMH-QTVIGLE 253
G LK+ A++ +++ + Y LGS + ++ H Q+VI E
Sbjct: 172 GSMVLKD----------AVNATLQEWASPSDDTFYVLGSAVGPAPFPEMVKHFQSVISTE 221
Query: 254 AKEQME--EFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--KAAPTMT 309
+K+Q++ E + PD+++ CVGGGSN G ++ D + + VE K A T
Sbjct: 222 SKQQLQAKEAQLPDMVVACVGGGSNAIGSFAAYIDD-----PSVQLVGVEAAGKGADT-D 275
Query: 310 RGVYTYDYGDSAGLTPKLK-MHTLGHRYYVPPIH--AGGLRYHGLAPTLSVLINHGIVKP 366
R T + G S G+ +K + + P++ + GL Y G+ P + L G +
Sbjct: 276 RTAATIERG-SVGIFHGMKSLFMQNEDGQIDPVYSISAGLDYPGVGPEHAALAQEGRAQY 334
Query: 367 IAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLL 426
+ E EA AK EGIV A ES HA+ A ++K A + K+ +I+ LSG G
Sbjct: 335 VGITDDEAVEAFTYIAKQEGIVAAIESCHAI-AYVEKI--APQMAKDQIIICTLSGRGDK 391
Query: 427 DLKGYEDY 434
D+ Y
Sbjct: 392 DVASIAKY 399
>sp|P43284|TRP2_MAIZE TRYPTOPHAN SYNTHASE BETA CHAIN 2 PRECURSOR (ORANGE PERICARP 2)
>gi|320135|pir||PQ0450 tryptophan synthase (EC 4.2.1.20)
beta-2 chain precursor - maize (fragment)
>gi|168574|gb|AAA33491.1| (M76685) tryptophan synthase
beta-subunit [Zea mays]
Length = 443
Score = 139 bits (347), Expect = 6e-32
Identities = 122/368 (33%), Positives = 174/368 (47%), Gaps = 39/368 (10%)
Query: 85 IGRPTPLFRATNL----EKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+GR +PL+ A L ++ GT IY K E TG+HKIN A+AQA AK+ G +R+
Sbjct: 98 VGRESPLYFAERLTEHYKRADGTGPLIYLKREDLNHTGAHKINNAVAQALLAKRLGKQRI 157
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + GL+ +YM +++ MR+ GAEV
Sbjct: 158 IAETGAGQHGVATATVCRRFGLQCIIYMGAQDMERQALNVFRMRLLGAEV-----RAVHS 212
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLE 253
G LK+ A SEAI D V E Y LGSV V VIG E
Sbjct: 213 GTATLKD----------ATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVREFHKVIGKE 262
Query: 254 AKEQ-MEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDV---LDGKSEYEFIAVEPKAAPTM 308
+ Q M+++ +PDV++ CVGGGSN GL + FV+D L G K A T+
Sbjct: 263 TRRQAMDKWGGKPDVLVACVGGGSNAMGLFHEFVEDQDVRLVGLEAAGHGVDTDKHAATL 322
Query: 309 TRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIA 368
T+G +G + L + + P + GL Y G+ P S L + G + +
Sbjct: 323 TKGQVGVLHGSMSYL-----LQDDDGQVIEPHSISAGLDYPGVGPEHSFLKDIGRAEYDS 377
Query: 369 YHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
E +A ++ EGI+PA E++HA+ A ++K +G +V+ N SG G D+
Sbjct: 378 VTDQEALDAFKRVSRLEGIIPALETSHAL-AYLEKLCPTLADGVRVVV--NCSGRGDKDV 434
Query: 429 KGYEDYLD 436
YLD
Sbjct: 435 HTASKYLD 442
>gb|AAA65169.1| (U23496) tryptophan synthase beta subunit [Escherichia coli]
Length = 397
Score = 139 bits (347), Expect = 6e-32
Identities = 126/387 (32%), Positives = 174/387 (44%), Gaps = 60/387 (15%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV--- 159
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-----EKARYSLGSVLNH------VLM 245
H GS + +A + L+D E A Y LG+ V
Sbjct: 160 --------------HSGS--ATLKDACNEGLRDWSGSYETAHYMLGTAAGPHPYPTIVRE 203
Query: 246 HQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPK 303
Q +IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 204 FQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPG 258
Query: 304 AAPTMTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTL 355
G+ T ++G G+ +K M T + + GL + + P
Sbjct: 259 G-----HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQH 313
Query: 356 SVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KE 413
+ L + G ++ E EA EGI+PA ES+HA + AL+ RE KE
Sbjct: 314 AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPEKE 369
Query: 414 MVILFNLSGHGLLDLKGYEDYLDGKLE 440
+++ NLSG G D+ D L + E
Sbjct: 370 QLLVVNLSGRGDKDIFTVHDILKARGE 396
>gb|AAA73814.1| (U25421) tryptophan synthase beta subunit [Escherichia coli]
Length = 397
Score = 139 bits (347), Expect = 6e-32
Identities = 127/383 (33%), Positives = 175/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K M T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E +A EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 STGRADYVSITDDEALKAFKTLCLHEGIIPALESSHA----LAHALKMMRENPDKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>gb|AAA73832.1| (U25425) tryptophan synthase beta subunit [Escherichia coli]
Length = 397
Score = 139 bits (347), Expect = 6e-32
Identities = 127/383 (33%), Positives = 175/383 (45%), Gaps = 52/383 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPGG--- 259
Query: 308 MTRGVYTYDYG-----DSAGLTPKLK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
G+ T ++G G+ +K + T + + GL + + P + L
Sbjct: 260 --HGIETGEHGAPLKHGRVGIYFGMKAPMIQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREG--KEMVIL 417
+ G ++ E EA EGI+PA ES+HA + AL+ RE KE +++
Sbjct: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA----LAHALKMMRENPDKEQLLV 373
Query: 418 FNLSGHGLLDLKGYEDYLDGKLE 440
NLSG G D+ D L + E
Sbjct: 374 VNLSGRGDKDIFTVHDILKARGE 396
>gi|6321412 tryptophan synthetase; Trp5p [Saccharomyces cerevisiae]
>gi|136373|sp|P00931|TRP_YEAST TRYPTOPHAN SYNTHASE
>gi|68333|pir||TSBYAB tryptophan synthase (EC 4.2.1.20)
- yeast (Saccharomyces cerevisiae)
>gi|4674|emb|CAA24635.1| (V01342) trp5 [Saccharomyces
cerevisiae] >gi|1322496|emb|CAA96727.1| (Z72548) ORF
YGL026c [Saccharomyces cerevisiae]
Length = 707
Score = 139 bits (346), Expect = 8e-32
Identities = 124/380 (32%), Positives = 175/380 (45%), Gaps = 53/380 (13%)
Query: 77 ELRKLYSKIGRPTPLFRATNL-EKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQ 135
+ + LYS IGRP+ L +A L E G A+I+ K E TGSHKIN ALAQ AK+
Sbjct: 341 DFKSLYSYIGRPSSLHKAERLTEHCQG--AQIWLKREDLNHTGSHKINNALAQVLLAKRL 398
Query: 136 GIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPS 195
G + ++ ETGAGQ G A + A A GL V+M +++ MRI GA+V +
Sbjct: 399 GKKNVIAETGAGQHGVATATACAKFGLTCTVFMGAEDVRRQALNVFRMRILGAKVIAVTN 458
Query: 196 ENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKAR-YSLGSVLNH------VLMHQT 248
G + L++ A SEA + + K Y +GS + V Q+
Sbjct: 459 -----GTKTLRD----------ATSEAFRFWVTNLKTTYYVVGSAIGPHPYPTLVRTFQS 503
Query: 249 VIGLEAKEQ---MEEFEEPDVIIGCVGGGSNFAGLAYPFVKDVL----------DGKSEY 295
VIG E KEQ M + PD ++ CVGGGSN G+ PF D DG
Sbjct: 504 VIGKETKEQFAAMNNGKLPDAVVACVGGGSNSTGMFSPFEHDTSVKLLGVEAGGDGVDTK 563
Query: 296 EFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTL 355
A P + GV TY DS G H++ + GL Y G+ P L
Sbjct: 564 FHSATLTAGRPGVFHGVKTYVLQDSDGQVH--DTHSV----------SAGLDYPGVGPEL 611
Query: 356 SVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMV 415
+ + G + IA + L ++ EGI+PA ES+HAV + A + + + +V
Sbjct: 612 AYWKSTGRAQFIAATDAQALLGFKLLSQLEGIIPALESSHAVYGACELA-KTMKPDQHLV 670
Query: 416 ILFNLSGHGLLDLKGYEDYL 435
I N+SG G D++ + L
Sbjct: 671 I--NISGRGDKDVQSVAEVL 688
>sp|P16578|TRP_COPCI TRYPTOPHAN SYNTHASE >gi|83890|pir||JU0401 tryptophan synthase (EC
4.2.1.20) - inky cap (Coprinus cinereus)
>gi|167217|gb|AAA51432.1| (M91661) tryptophan synthetase
[Coprinus cinereus]
Length = 702
Score = 138 bits (345), Expect = 1e-31
Identities = 121/399 (30%), Positives = 185/399 (46%), Gaps = 51/399 (12%)
Query: 59 EELVKQEISRERYIEIPG---ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGAT 115
+ L + E + + IE P E+R LY+ RP+ L+ A NL K G A I+ K E
Sbjct: 314 DALAELEEAHKSAIEDPAFWEEVRSLYTYSNRPSNLYLAENLTKEAGG-ANIWLKREDLN 372
Query: 116 VTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQ 175
TGSHKIN AL Q AK+ G R++ ETGAGQ G A + A GL+ +YM ++
Sbjct: 373 HTGSHKINNALGQILLAKRIGKTRIIAETGAGQHGVATATVCAKFGLECVIYMGAEDVRR 432
Query: 176 KPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARY 234
+ + + + G + + P + G LK+ A++EA+ D V Y
Sbjct: 433 QALKLFRIEMLGGKAWVIPVHS---GSCTLKD----------AVNEAMRDWVTNLSTTHY 479
Query: 235 SLGSVLNH------VLMHQTVIGLEAKEQMEEF--EEPDVIIGCVGGGSNFAGLAYPFVK 286
+GS + V Q VIG E K Q++E + PDV++ CVGGGSN G Y F+
Sbjct: 480 LVGSAIGPHPFPTIVRDFQKVIGEEIKAQLKEVRGKLPDVVVACVGGGSNAIGTFYDFIP 539
Query: 287 DVL----------DGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRY 336
D +G ++ A P + GV TY D AG ++ H++
Sbjct: 540 DKSVRLVGVEAGGEGIDGHKHSATLSMGQPGVLHGVRTYILQDKAGQI--IETHSI---- 593
Query: 337 YVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHA 396
+ GL Y G+ P + L + G + + + + EGI+PA ES+HA
Sbjct: 594 ------SAGLDYPGVGPEHAWLKDSGRADYVVCTDEDALRGFRMLTQKEGIIPALESSHA 647
Query: 397 VKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYL 435
+ + K ++ + K++VI LSG G D++ + L
Sbjct: 648 IWEGV-KIAKSLPKDKDIVIC--LSGRGDKDVEQISELL 683
>sp|P22097|TRPB_VIBPA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|48490|emb|CAA35035.1| (X17149)
tryptophan synthase; beta subunit [Vibrio
parahaemolyticus]
Length = 396
Score = 138 bits (344), Expect = 1e-31
Identities = 127/389 (32%), Positives = 173/389 (43%), Gaps = 49/389 (12%)
Query: 59 EELVKQEISRERYIEIPGELRKLYSKI-GRPTPLFRATNLEKLLGTPARIYFKYEGATVT 117
E+L + I + E E L + GRPT L NL K GT ++Y K E
Sbjct: 25 EQLEQAFIDAQEDPEFRSEFMTLLQEYAGRPTALTLTRNLTK--GTKTKLYLKREDLLHG 82
Query: 118 GSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKP 177
G+HK N L QA AK+ G ++ ETGAGQ G A +LA ALLGLK RVYM +++
Sbjct: 83 GAHKTNQVLGQALLAKRMGKHEIIAETGAGQHGVATALACALLGLKCRVYMGAKDVERQS 142
Query: 178 YRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSL 236
M++ GAEV P S G LK+ A +EA+ D E A Y L
Sbjct: 143 PNVFRMKLMGAEVIPVHS-----GSATLKD----------ACNEALRDWSGSYEDAHYLL 187
Query: 237 GSVLNH------VLMHQTVIGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDV 288
G+ V Q +IG E K Q+ E PD +I CVGGGSN G+ F+++
Sbjct: 188 GTAAGPHPFPTIVREFQRMIGEETKNQILAREGRLPDAVIACVGGGSNAIGMFADFIEE- 246
Query: 289 LDGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSA---------GLTPKLKMHTLGHRYYVP 339
I VEP +G+ T +G G+ L G
Sbjct: 247 ----ESVRLIGVEPAG-----KGIDTDQHGAPLKHGKTGIFFGMKAPLMQDENGQVEESY 297
Query: 340 PIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKA 399
+ A GL + + P + L G + E EA A++EGI+PA ES+HA+
Sbjct: 298 SVSA-GLDFPSVGPQHAHLNAIGRAEYDNVTDDEALEAFQELARSEGIIPALESSHALAH 356
Query: 400 VIDKALEARREGKEMVILFNLSGHGLLDL 428
+ A E KE +++ NLSG G D+
Sbjct: 357 ALRMARE--NPEKEQLLVVNLSGRGDKDI 383
>sp|P43283|TRP1_MAIZE TRYPTOPHAN SYNTHASE BETA CHAIN 1 (ORANGE PERICARP 1)
>gi|320136|pir||PQ0449 tryptophan synthase (EC 4.2.1.20)
beta-1 chain - maize (fragment)
>gi|168572|gb|AAA33490.1| (M76684) tryptophan synthase
beta-subunit [Zea mays]
Length = 389
Score = 138 bits (343), Expect = 2e-31
Identities = 122/373 (32%), Positives = 175/373 (46%), Gaps = 49/373 (13%)
Query: 85 IGRPTPLFRATNL----EKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+GR +PL+ A L ++ GT IY K E G+HKIN A+AQA AK+ G +R+
Sbjct: 44 VGRESPLYFAERLTEHYKRADGTGPLIYLKREDLNHRGAHKINNAVAQALLAKRLGKQRI 103
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A GL+ +YM +++ M++ GAEV
Sbjct: 104 IAETGAGQHGVATATVCARFGLQCIIYMGAQDMERQALNVFRMKLLGAEV-----RAVHS 158
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLE 253
G LK+ A SEAI D V E Y LGSV V VIG E
Sbjct: 159 GTATLKD----------ATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVREFHKVIGKE 208
Query: 254 AKEQ-MEEF-EEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVE--------PK 303
+ Q M ++ +PDV++ CVGGGSN GL + FV+D + I VE K
Sbjct: 209 TRRQAMHKWGGKPDVLVACVGGGSNAMGLFHEFVED-----QDVRLIGVEAAGHGVDTDK 263
Query: 304 AAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGI 363
A T+T+G +G + L + + P + GL Y G+ P S L + G
Sbjct: 264 HAATLTKGQVGVLHGSMSYL-----LQDDDGQVIEPHSISAGLDYPGVGPEHSFLKDIGR 318
Query: 364 VKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGH 423
+ + E +A ++ EGI+PA E++HA+ A ++K +G +V+ N SG
Sbjct: 319 AEYDSVTDQEALDAFKRVSRLEGIIPALETSHAL-AYLEKLCPTLPDGVRVVL--NCSGR 375
Query: 424 GLLDLKGYEDYLD 436
G D+ YLD
Sbjct: 376 GDKDVHTASKYLD 388
>sp|P42391|TRPB_BUCAP TRYPTOPHAN SYNTHASE BETA CHAIN >gi|625652|pir||C49897 tryptophan
synthase (EC 4.2.1.20) beta chain - Buchnera aphidicola
>gi|396658|emb|CAA79500.1| (Z19055) beta subunit of
tryptophan synthetase [Buchnera aphidicola]
Length = 399
Score = 138 bits (343), Expect = 2e-31
Identities = 120/361 (33%), Positives = 169/361 (46%), Gaps = 49/361 (13%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL NL GT RIY K E G+HK N L QA A K + ++ ETG
Sbjct: 53 GRPTPLTLCNNLTN--GTKTRIYLKREDLLHGGAHKTNQVLGQAMLAVKMKKKEIIAETG 110
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A ++A AL LK ++YM +++ M++ GAEV + E G L
Sbjct: 111 AGQHGVAAAIASALFNLKCKIYMGYKDIKRQSPNVFRMKLMGAEVV-----SVESGSGTL 165
Query: 206 KEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTVIGLEAKEQM 258
K+ A +EA+ D ++ +K+ Y +G+ V Q +IG EAK+Q+
Sbjct: 166 KD----------ACNEALRDWSRNYQKSHYMIGTAAGPHPYPTIVKEFQKMIGEEAKKQI 215
Query: 259 EEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
E E PD II CVGGGSN G+ F+ + + I VEP +G+ T
Sbjct: 216 LEQENRLPDAIIACVGGGSNAIGIFSDFIDE------DVNLIGVEPAG-----QGIETGK 264
Query: 317 YG-----DSAGLTPKLKMHTL----GHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPI 367
+G G+ +K H + G I A GL + + P S L + K +
Sbjct: 265 HGAPLNHGRTGIYFGMKSHLMQSQEGQIEKSWSISA-GLDFPSVGPEHSWLNSIHRAKYV 323
Query: 368 AYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLD 427
+ E EA + +K EGI+PA ES+HA+ + L KE V + NLSG G D
Sbjct: 324 SITDIEALEAFQILSKKEGIIPALESSHALAYAL--KLMYLDPKKEQVFIVNLSGRGDKD 381
Query: 428 L 428
+
Sbjct: 382 I 382
>sp|Q44687|TRPB_BUCMH TRYPTOPHAN SYNTHASE BETA CHAIN >gi|6492283|gb|AAF14254.1|AF132318_4
(AF132318) beta subunit of tryptophan synthetase
[Buchnera aphidicola]
Length = 392
Score = 138 bits (343), Expect = 2e-31
Identities = 114/368 (30%), Positives = 170/368 (45%), Gaps = 48/368 (13%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL NL K GT +IY K E G+HK N L QA AKK + ++ ETG
Sbjct: 53 GRPTPLTLCRNLTK--GTKTKIYLKREDLLHGGAHKTNQVLGQALLAKKMKKKEIIAETG 110
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A + + ALL LK R+YM ++ M++ GAEV P + +
Sbjct: 111 AGQHGVAAAFSCALLNLKCRIYMGLKDINRQQQNVFRMKLMGAEVIPVKTGS-------- 162
Query: 206 KEDPNHPGSLGIAISEAIEDVLKDE-KARYSLGSVLNH------VLMHQTVIGLEAKEQM 258
G+L A +EA+ D ++ A Y LG+ V Q++IG E K Q+
Sbjct: 163 -------GTLKDACNEALRDWSENYINAHYMLGTAAGPHPYPTIVKEFQSIIGKETKRQI 215
Query: 259 --EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
EE P+ +I CVGGGSN G+ F+ D + I VEP +G++T
Sbjct: 216 VREENCLPNAVIACVGGGSNAIGIFSSFISD-----NSVSLIGVEPGG-----KGIHTNK 265
Query: 317 YGDSA---------GLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPI 367
+G G+ K+ G I A GL + + P + L + + +
Sbjct: 266 HGAPLTHGETGIFFGMKTKIMQTEEGQIKESWSISA-GLDFPAVGPEHAWLYSTKRAQYV 324
Query: 368 AYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLD 427
+ E A +K+EGI+PA ES+HA+ + L K +++ N+SG G D
Sbjct: 325 SITDHEAVNAFRCLSKSEGIIPALESSHALAYAL--KLMNNHPQKNQILIVNISGRGDKD 382
Query: 428 LKGYEDYL 435
++ +++L
Sbjct: 383 IETVKNFL 390
>sp|O50046|TRPB_CAMAC TRYPTOPHAN SYNTHASE BETA CHAIN 2 PRECURSOR
>gi|2792520|gb|AAB97087.1| (AF042320) tryptophan
synthase beta subunit [Camptotheca acuminata]
>gi|2801771|gb|AAB97526.1| (AF042321) tryptophan
synthase beta [Camptotheca acuminata]
Length = 466
Score = 137 bits (342), Expect = 2e-31
Identities = 124/360 (34%), Positives = 170/360 (46%), Gaps = 39/360 (10%)
Query: 85 IGRPTPLFRATNL----EKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+GR +PL+ A L ++ G IY K E TG+HKIN A+AQA AK+ G +R+
Sbjct: 121 VGRESPLYFAERLTLHYKRPNGEGPEIYLKREDLNHTGAHKINNAVAQALLAKRLGKKRI 180
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A GL+ +YM +++ MR+ GAEV
Sbjct: 181 IAETGAGQHGVATATVCARFGLQCVIYMGAQDMERQALNVFRMRLLGAEV-----RAVHS 235
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLE 253
G LK+ A SEAI D V E Y LGSV V VIG E
Sbjct: 236 GTATLKD----------ATSEAIRDWVTNVESTHYILGSVAGPHPYPMMVREFHAVIGKE 285
Query: 254 AKEQMEE--FEEPDVIIGCVGGGSNFAGLAYPFV--KDV-LDGKSEYEFIAVEPKAAPTM 308
++Q E +PDV++ CVGGGSN GL + FV KDV + G F K A T+
Sbjct: 286 TRKQALEKWGGKPDVLVACVGGGSNAMGLFHEFVDDKDVRMIGVEAAGFGLDSGKHAATL 345
Query: 309 TRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIA 368
T+G + G G L G + P + GL Y G+ P S L + G +
Sbjct: 346 TKG----EVGVLHGAMSYLLQDDDG-QIIEPHSISAGLDYPGVGPEHSFLKDIGRAEYYC 400
Query: 369 YHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDL 428
E EA ++ EGI+PA E++HA+ A ++K G ++V+ N SG G D+
Sbjct: 401 CTDEEALEAFKRLSRLEGIIPALETSHAL-AFLEKLCPTLPNGTKVVL--NCSGRGDKDV 457
>sp|O13831|TRP_SCHPO TRYPTOPHAN SYNTHASE >gi|7493535|pir||T37946 tryptophan synthase (EC
4.2.1.20) - fission yeast (Schizosaccharomyces pombe)
>gi|2388914|emb|CAB11651.1| (Z98974) tryptophan synthase
(EC 4.2.1.20) [Schizosaccharomyces pombe]
Length = 697
Score = 137 bits (341), Expect = 3e-31
Identities = 119/371 (32%), Positives = 174/371 (46%), Gaps = 36/371 (9%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
E R Y +GRP+ L A L + G A I+ K E GSHKIN + Q AK+ G
Sbjct: 338 EFRSYYEYMGRPSALDYAKRLTEYCGG-AHIWLKREDLNHGGSHKINNCIGQILLAKRLG 396
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
R++ ETGAGQ G A ++ A G+K +YM +++ +R+ GAEV P S
Sbjct: 397 KNRIIAETGAGQHGVATAICAAKFGMKCTIYMGAEDCRRQALNVFRIRLLGAEVVPVTS- 455
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTV 249
G + L++ A++EA++ V + + Y +GS + V Q+V
Sbjct: 456 ----GTQTLRD----------AVNEALKAWVEQIDTTHYLIGSAIGPHPFPTIVKTFQSV 501
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFV--KDVLDGKSEYEFIAVE-PKA 304
IG E K QM+E + PD ++ CVGGGSN G+ PF K V+ E V+ PK
Sbjct: 502 IGEETKAQMQEKRKKLPDAVVACVGGGSNSIGMFSPFKADKSVMMLGCEAGGDGVDTPKH 561
Query: 305 APTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIV 364
+ T+T G G G+ + G I A GL Y G+ P LS L
Sbjct: 562 SATLTMG----KVGVFHGVRTYVLQREDGQIQDTHSISA-GLDYPGVGPELSELKYTNRA 616
Query: 365 KPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHG 424
+ IA + E EGI+PA ES+HAV ++ A++ K+ I+ +SG G
Sbjct: 617 EFIAVTDAQCLEGFRALCHLEGIIPALESSHAVYGGMEL---AKKLPKDKDIVITISGRG 673
Query: 425 LLDLKGYEDYL 435
D++ + L
Sbjct: 674 DKDVQSVAEQL 684
>pir||C82688 tryptophan synthase beta chain XF1375 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106380|gb|AAF84184.1|AE003969_1 (AE003969)
tryptophan synthase beta chain [Xylella fastidiosa]
Length = 449
Score = 137 bits (341), Expect = 3e-31
Identities = 118/369 (31%), Positives = 173/369 (45%), Gaps = 50/369 (13%)
Query: 79 RKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIE 138
+ L +GRP+P++ A L + +G A+I K E TG+HKIN + QA A + G
Sbjct: 101 KDLKDYVGRPSPIYHAERLSRKVGG-AQILLKREDLNHTGAHKINNTIGQALLAARMGKT 159
Query: 139 RLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENT 198
R++ ETGAGQ G A + A LGL+ VYM +++ M++ GA V P S
Sbjct: 160 RIIAETGAGQHGVASATVAARLGLECVVYMGATDIERQQINVYRMKLLGATVVPVTS--- 216
Query: 199 EVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIG 251
G LK+ A++EA+ D V Y +G+V V ++G
Sbjct: 217 --GSATLKD----------ALNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVG 264
Query: 252 LEAKEQM-EEFEE-PDVIIGCVGGGSNFAGLAYPFVKD----VLDGKSEYEFIAVEPKAA 305
EA+ QM E++ PD + CVGGGSN GL + F+ D + ++ + IA AA
Sbjct: 265 REARAQMIEDYGRLPDAMTACVGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAA 324
Query: 306 ------PTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
P + G TY D G L+ H++ + GL Y G+ P + L
Sbjct: 325 SIVAGRPGVLHGNRTYVVCDDDGQI--LETHSV----------SAGLDYPGVGPEHAFLA 372
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFN 419
+ G V+ + E A L A EGI+ A ES+HAV + AR K+ ++L N
Sbjct: 373 DSGRVQYVGIRDEEALAAFHLLAHTEGILAALESSHAVAHAMTL---ARDLPKDALVLCN 429
Query: 420 LSGHGLLDL 428
LSG G D+
Sbjct: 430 LSGRGDKDV 438
>sp|O68428|TRPB_BUCDN TRYPTOPHAN SYNTHASE BETA CHAIN >gi|3170097|gb|AAC27735.1|
(AF038565) tryptophan synthase large subunit [Buchnera
aphidicola]
Length = 397
Score = 136 bits (340), Expect = 4e-31
Identities = 119/368 (32%), Positives = 166/368 (44%), Gaps = 48/368 (13%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL NL K GT RIY K E G+HK N L QA A + ++ ETG
Sbjct: 53 GRPTPLTLCNNLTK--GTKTRIYLKREDLLHGGAHKTNQVLGQAILAIRMKKNEIIAETG 110
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A ++A ALL LK R+YM +++ M++ GAEV P
Sbjct: 111 AGQHGVATAIACALLNLKCRIYMGIKDIKRQHPNVFRMKLMGAEVIPV------------ 158
Query: 206 KEDPNHPGSLGIAISEAIEDVLKDEK-ARYSLGSVLNH------VLMHQTVIGLEAKEQM 258
N G+L A +EA+ D K + Y +G+ V Q +IG E K+Q+
Sbjct: 159 ---KNGSGTLKDACNEALRDWSNSYKNSHYMIGTAAGPHPYPTIVREFQKIIGEETKQQI 215
Query: 259 --EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
+E + P+ II CVGGGSN G+ F+ D E I VEP +G+ T
Sbjct: 216 LEQETKLPNAIIACVGGGSNAIGIFSNFIND-----KEVSLIGVEPGG-----KGIKTGQ 265
Query: 317 YG-----DSAGLTPKLKMHTL----GHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPI 367
+G G+ +K H + G I A GL + + P + L + + +
Sbjct: 266 HGAPLKHGRTGIFFGMKSHLMQDQEGQIQESWSISA-GLDFPSVGPEHAWLNSINRAQYV 324
Query: 368 AYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLD 427
+ E + L K EGI+PA ES+HA+ + L KE + + NLSG G D
Sbjct: 325 SITDQEALDTFQLLCKKEGIIPALESSHALAYAL--KLMNLSPKKEQIFVVNLSGRGDKD 382
Query: 428 LKGYEDYL 435
+ D L
Sbjct: 383 IFTVHDIL 390
>sp|Q9X4E5|TRPB_RHOSH TRYPTOPHAN SYNTHASE BETA CHAIN >gi|4761127|gb|AAD29261.1|AF107093_6
(AF107093) tryptophan synthase beta chain [Rhodobacter
sphaeroides]
Length = 409
Score = 135 bits (337), Expect = 9e-31
Identities = 116/365 (31%), Positives = 168/365 (45%), Gaps = 52/365 (14%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
+GRP+PL+ A L + LG A+IY K + TG+HKIN L Q A++ G R++ ET
Sbjct: 63 VGRPSPLYFAPRLTEHLGG-AKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAET 121
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAGQ G A + A GLK VYM +++ MR+ GAEV P S
Sbjct: 122 GAGQHGVATATVCAKFGLKCVVYMGAHDVERQAPNVFRMRLLGAEVVPVTSGR------- 174
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VLMHQTVIGLEAKEQ 257
G+L A+++A+ D V Y +G+V V Q++IG E + Q
Sbjct: 175 --------GTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQSIIGREVRWQ 226
Query: 258 MEEFEE---PDVIIGCVGGGSNFAGLAYPFVKDV--------LDGKS---EYEFIAVEPK 303
+ E EE PD ++ +GGGSN GL +PF+ D GK E A
Sbjct: 227 LAEQEEGRLPDTLVAAIGGGSNAMGLFHPFLDDPSVRIVGVEAGGKGVDDRMEHCASLTG 286
Query: 304 AAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGI 363
P + G TY D+ G L+ ++ + GL Y G+ P + L + G
Sbjct: 287 GRPGVLHGNRTYLLQDADGQI--LEGFSI----------SAGLDYPGIGPEHAWLHDTGR 334
Query: 364 VKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGH 423
+ ++ E EA L EGI+PA E +HA+ VI A R + +I+ N+ G
Sbjct: 335 AEYVSITDAEALEAFQLCCALEGIIPALEPSHALAHVIKIAPTLPR---DHIIVMNMCGR 391
Query: 424 GLLDL 428
G D+
Sbjct: 392 GDKDI 396
>sp|P11080|TRPB_PSEPU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|77778|pir||B30768 tryptophan
synthase (EC 4.2.1.20) beta chain - Pseudomonas putida
>gi|45749|emb|CAA31661.1| (X13299) trpB gene product (AA
1 - 405) [Pseudomonas putida]
Length = 405
Score = 134 bits (333), Expect = 3e-30
Identities = 111/364 (30%), Positives = 172/364 (46%), Gaps = 50/364 (13%)
Query: 85 IGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTET 144
IGRP PL+ A L + G A+I+FK E TG+HK+N + Q AK+ G +RL+ ET
Sbjct: 60 IGRPNPLYFAERLTEHCGG-AKIFFKREELNHTGAHKVNNCIGQVLLAKRMGKKRLIAET 118
Query: 145 GAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRF 204
GAG G A + A GL +YM +++ M++ GAE+ P +
Sbjct: 119 GAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLLGAEIVPVTAGT------- 171
Query: 205 LKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQ 257
G+L A++EA+ D V E Y +G+V V Q++IG E + Q
Sbjct: 172 --------GTLKDAMNEALRDWVTNVEDTFYLIGTVAGPHPYPAMVRDFQSIIGKETRAQ 223
Query: 258 MEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTY 315
++E E PD ++ CVGGGSN GL + F+++ + I VE GV+T
Sbjct: 224 LQEKEGRLPDSLVACVGGGSNAMGLFHEFLEE-----PSVQIIGVEAGG-----HGVHTD 273
Query: 316 DYGDSAGLTPKLKMHTLGHRYY--------VPPIH--AGGLRYHGLAPTLSVLINHGIVK 365
+ S +H G+R Y + H + GL Y G+ P + L V+
Sbjct: 274 KHAASLNGGVPGVLH--GNRTYLLQDEDGQITDAHSISAGLDYPGIGPEHAYLHEVKRVE 331
Query: 366 PIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGL 425
++ E +A + EGI+PA ES+HA+ I + A + K+ +++ LSG G
Sbjct: 332 YVSITDDEALDAFHATCRLEGIIPALESSHALAEAIKR---APKLPKDHLMVVCLSGRGD 388
Query: 426 LDLK 429
D++
Sbjct: 389 KDMQ 392
>sp|O84172|TRPB_CHLTR TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437000|pir||A71547 tryptophan
synthase (EC 4.2.1.20) beta chain - Chlamydia
trachomatis (serotype D, strain UW3/Cx)
>gi|3328574|gb|AAC67761.1| (AE001291) Tryptophan
Synthase (Beta Chain) [Chlamydia trachomatis]
Length = 392
Score = 133 bits (332), Expect = 3e-30
Identities = 115/368 (31%), Positives = 161/368 (43%), Gaps = 62/368 (16%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GR TPL N + + P R++ K E TG+HK+N AL Q AK G R+V ETG
Sbjct: 50 GRQTPLTEVKNFARAIDGP-RVFLKREDLLHTGAHKLNNALGQCLLAKYLGKTRVVAETG 108
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ G A + A A LGL VYM +++ MR GAEV V K
Sbjct: 109 AGQHGVATATACAYLGLDCVVYMGAKDVERQKPNVEKMRFLGAEV-------VSVTK--- 158
Query: 206 KEDPNHPGSLGI--AISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKE 256
GS G+ A+++A++D Y LGS L + V Q+VI E KE
Sbjct: 159 -------GSCGLKDAVNQALQDWATTHSFTHYCLGSALGPLPYPDIVRFFQSVISAEVKE 211
Query: 257 QMEEF--EEPDVIIGCVGGGSNFAGLAYPFVKD--------------VLDGKSEYEFIAV 300
Q+ +PD++I C+GGGSN G + F+ + + GK F
Sbjct: 212 QIHAVAGRDPDILIACIGGGSNAIGFFHHFIPNPKVQLIGVEGGGLGISSGKHAARFAT- 270
Query: 301 EPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLIN 360
P + G Y+Y D G L+ H++ + GL Y + P + +
Sbjct: 271 ---GRPGVFHGFYSYLLQDDDGQV--LQTHSI----------SAGLDYPSVGPDHAEMHE 315
Query: 361 HGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNL 420
G E A L + EGI+PA ES+HA+ ++ A KE +++ NL
Sbjct: 316 SGRAFYTLATDEEALRAFFLLTRNEGIIPALESSHALAHLVSIAPSL---PKEQIVIVNL 372
Query: 421 SGHGLLDL 428
SG G DL
Sbjct: 373 SGRGDKDL 380
>pir||T04330 probable tryptophan synthase (EC 4.2.1.20) beta chain - rice
>gi|2081609|dbj|BAA19928.1| (AB003491) tryptophan
synthase B [Oryza sativa]
Length = 470
Score = 132 bits (330), Expect = 6e-30
Identities = 120/373 (32%), Positives = 169/373 (45%), Gaps = 47/373 (12%)
Query: 85 IGRPTPLFRATNLEKLL----GTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERL 140
+GR +PL+ +L + GT IY K E TG+HKIN A+AQA AK+ G +R+
Sbjct: 123 VGRLSPLYFVESLTEHYRRENGTGPLIYLKREDNNHTGAHKINNAVAQALSAKRLGKKRI 182
Query: 141 VTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEV 200
+ ETGAGQ G A + A GL+ +YM +++ M++ GAEV
Sbjct: 183 IAETGAGQHGVATATVCASFGLECIIYMGAQDMERQALNVFRMKLLGAEV---------- 232
Query: 201 GKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLE 253
+E + +L A SEAI D V E Y LGSV V VIG E
Sbjct: 233 -----REVHSGTATLKDATSEAIRDWVTNVENTHYILGSVAGPHPYPMMVREFHKVIGKE 287
Query: 254 AKEQMEE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEP--------K 303
+ Q E +PDV++ CVGGGSN GL + FV D E I VE K
Sbjct: 288 TRRQALEKWGGKPDVLVACVGGGSNAMGLFHEFVDD-----QEVRMIGVEAAGFGVDSVK 342
Query: 304 AAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGI 363
A T+T+G +G L + + P + GL Y G+ P S + + G
Sbjct: 343 HAATLTKGDVGVLHG---SLAMSYLLQDDDGQVIEPHSISAGLDYPGVGPEHSFVKDMGR 399
Query: 364 VKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGH 423
+ + E ++ EGI+PA E++HA+ A ++K +G +V FN SG
Sbjct: 400 AEYDSATDEEALAGFKRVSRLEGIIPALETSHAL-AYLEKLCPTLFDGTRVV--FNFSGR 456
Query: 424 GLLDLKGYEDYLD 436
G D+ LD
Sbjct: 457 GDKDVDTVAKSLD 469
>sp|P43760|TRPB_HAEIN TRYPTOPHAN SYNTHASE BETA CHAIN >gi|1075400|pir||I64122 tryptophan
synthase (EC 4.2.1.20) beta chain - Haemophilus
influenzae (strain Rd KW20) >gi|1574269|gb|AAC23078.1|
(U32822) tryptophan synthase beta subunit (trpB)
[Haemophilus influenzae Rd]
Length = 397
Score = 131 bits (327), Expect = 1e-29
Identities = 124/384 (32%), Positives = 174/384 (45%), Gaps = 60/384 (15%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L NL K GT ++Y K E G+HK N L Q AK+ G
Sbjct: 48 DLLKNYA--GRPTALTLCRNLTK--GTKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMG 103
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
R++ ETGAGQ G A +LA A+L + RVYM +++ MR+ GAEV P
Sbjct: 104 KTRIIAETGAGQHGVATALACAMLDMPCRVYMGAKDVERQSPNVFRMRLMGAEVIP---- 159
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
+ G LK+ A EA+ D + E Y LG+ V Q +
Sbjct: 160 -VQKGSCSLKD----------ACCEAMRDWSANYETTHYLLGTAAGPHPFPTIVREFQKM 208
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I VGGGSN G+ F+ + S I VEP
Sbjct: 209 IGEETKRQILEREGRLPDTVIAAVGGGSNAIGMFADFIDE-----SNVRLIGVEPAG--- 260
Query: 308 MTRGVYTYDYGDSAGLTPKLKMHTLGHRYYV-PPIH-------------AGGLRYHGLAP 353
+G+ T ++G LK T G + + PI + GL + + P
Sbjct: 261 --KGIETGEHG------APLKHGTTGIYFGMKSPIMQDKDGQIEESYSISAGLDFPSVGP 312
Query: 354 TLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKE 413
+ L G ++ E A AK EGI+PA ES+HA+ + K ++ E KE
Sbjct: 313 QHAYLNEIGRADYVSITDEEALNAFQELAKHEGIIPALESSHALAYAL-KLIKQNPE-KE 370
Query: 414 MVILFNLSGHGLLDLKGYEDYLDG 437
+++ NLSG G D+ + L+G
Sbjct: 371 QLLVVNLSGRGDKDIFTVDKILNG 394
>sp|Q59992|TRPB_SYNY3 TRYPTOPHAN SYNTHASE BETA CHAIN >gi|7437004|pir||S75990 tryptophan
synthase (EC 4.2.1.20) beta chain - Synechocystis sp.
(strain PCC 6803) >gi|295259|gb|AAA27302.1| (L14596)
tryptophan synthase beta subunit [Synechocystis sp.]
>gi|1001350|dbj|BAA10837.1| (D64006) tryptophan synthase
beta subunit [Synechocystis sp.]
>gi|741993|prf||2008311A Trp synthase:SUBUNIT=beta
[Synechocystis sp.]
Length = 412
Score = 131 bits (326), Expect = 2e-29
Identities = 136/421 (32%), Positives = 185/421 (43%), Gaps = 58/421 (13%)
Query: 32 LPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPL 91
+PE L P L E EE + + F EEL L K Y +GR +PL
Sbjct: 29 VPETLMPALT-ELEEAYYRYRAESSFQEELAG--------------LLKDY--VGRSSPL 71
Query: 92 FRATNLEKLL----GTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAG 147
+ A L GT IY K E TG+HKIN AL Q AK+ G +R++ ETGAG
Sbjct: 72 YFAERLSAHYARPDGTYPLIYLKREDLNHTGAHKINNALGQVLLAKRMGKKRIIAETGAG 131
Query: 148 QWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKE 207
Q G A + A GL+ +YM +++ M + GA V P +
Sbjct: 132 QHGVATATVCARFGLECIIYMGVQDMERQKLNVFRMNLLGARVQPVTAGT---------- 181
Query: 208 DPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLN------HVLMHQTVIGLEAKEQ-ME 259
G+L A SEAI D V E Y LGSV V VIG E ++Q ++
Sbjct: 182 -----GTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHRVIGQETRQQALK 236
Query: 260 EFEE-PDVIIGCVGGGSNFAGLAYPFVKDV---LDGKSEYEFIAVEPKAAPTMTRGVYTY 315
++ PD+++ CVGGGSN GL Y F+ + L G V K A T+T G
Sbjct: 237 KWGGLPDILLACVGGGSNAMGLFYDFIDEPAVRLIGIEAAGESIVSGKHAATLTMGKPGV 296
Query: 316 DYGD-SAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEV 374
+G S L K T H + GL Y G+ P S L + G + + E
Sbjct: 297 LHGAMSYLLQDKEGQVTEAHSI------SAGLDYPGVGPEHSYLKDAGRAEYYSVTDQEA 350
Query: 375 FEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDY 434
A ++ EGI+PA E+AHA A ++ + G+ +VI N SG G D++ Y
Sbjct: 351 ITALQRLSQLEGIIPALETAHAF-AYLETLCPQLKNGERIVI--NCSGRGDKDVQTVAKY 407
Query: 435 L 435
L
Sbjct: 408 L 408
>sp|P06561|TRPB_BRELA TRYPTOPHAN SYNTHASE BETA CHAIN >gi|80602|pir||F24723 tryptophan
synthase (EC 4.2.1.20) beta chain - Corynebacterium
glutamicum >gi|39597|emb|CAA28627.1| (X04960) trpB (AA
1-416) [Corynebacterium glutamicum]
Length = 416
Score = 126 bits (314), Expect = 4e-28
Identities = 126/418 (30%), Positives = 181/418 (43%), Gaps = 70/418 (16%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTP---AR 106
+++L++ F + E E + G LR +GRPTPL +NL L G AR
Sbjct: 33 LDQLEKAFVDATNSPEFREE----LGGYLRDY---LGRPTPLTECSNLP-LAGEGKGFAR 84
Query: 107 IYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRV 166
I+ K E G+HK N + Q AK+ G R++ ETGAGQ GTA +LA AL+GL+ V
Sbjct: 85 IFLKREDLVHGGAHKTNQVIGQVLLAKRMGKTRIIAETGAGQHGTATALACALMGLECVV 144
Query: 167 YMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED- 225
YM ++ M+++GA+V P S + G+L A++EA+ D
Sbjct: 145 YMGAKDVARQQPNVYRMQLHGAKVIPVESGS---------------GTLKDAVNEALRDW 189
Query: 226 VLKDEKARYSLGSVLNH------VLMHQTVIGLEAKEQMEE--FEEPDVIIGCVGGGSNF 277
++ Y LG+ V VI EAK QM E + PDV++ CVGGGSN
Sbjct: 190 TATFHESHYLLGTRAGPHPFPTIVREFHKVISEEAKAQMLERTGKLPDVVVACVGGGSNA 249
Query: 278 AGLAYPFVKDVLDGKSEYEFIAVEP--------KAAPTMTRGVYTYDYGDSAGLTPKLKM 329
G+ F+ D E + EP K T+T G G G L
Sbjct: 250 IGMFADFIDD-----EGVELVGAEPAGEGLDSGKHGATITNG----QIGILHGTRSYLMR 300
Query: 330 HTLGHRYYVPPIHAG------GLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAK 383
++ G I AG G H P + KP + + A+
Sbjct: 301 NSDGQVEESYSISAGLDYPGVGHSTHTCTPPARTTLVSPTPKPSKHSSS--------LAR 352
Query: 384 AEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLDGKLED 441
EGI+P V+ + +A A EG+ + IL +LSG G D+ D+ G LE+
Sbjct: 353 YEGIIPRTGILTRVRLRLKRAKTAEEEGQNLTILVSLSGRGDKDV----DHRAGTLEE 406
>sp|P18285|TRPB_HALVO TRYPTOPHAN SYNTHASE BETA CHAIN >gi|99231|pir||B36044 tryptophan
synthase (EC 4.2.1.20) beta chain [validated] -
Haloferax volcanii (strain WFD11)
>gi|149043|gb|AAA72863.1| (M36177) tryptophan synthetase
B (trpB) [Haloferax volcanii]
Length = 423
Score = 125 bits (312), Expect = 8e-28
Identities = 120/398 (30%), Positives = 168/398 (42%), Gaps = 73/398 (18%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL RA L + +Y K E G+HK+N AL Q AK G ER++ ETG
Sbjct: 54 GRPTPLQRADRLSERYDR--EVYLKREDLLHGGAHKLNNALGQVLLAKYMGKERIIAETG 111
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ GTA ++A A L + +YM ++ M++ G+EV P VG+ L
Sbjct: 112 AGQHGTATAMACAHLDMPCEIYMGERDINRQRPNVFRMKLNGSEVNP-----VTVGRGTL 166
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQM 258
KE AISE + D E Y +GSV+ + V Q+VI EA+ Q
Sbjct: 167 KE----------AISETMRDWETNVEDTHYVIGSVVGPHPFPSMVRDFQSVISEEARTQA 216
Query: 259 EE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYD 316
E PD ++ C GGGSN G FV D E A + G T +
Sbjct: 217 REKLGRLPDAVVACAGGGSNTMGAFAEFVDD-------------EETALYAVEAGGSTLE 263
Query: 317 YGDSAGLTPKLKMHTLGHRYYVPPIH-----------------AGGLRYHGLAPTLSVLI 359
+ AG+ P T G + + GL Y G+ P L+ L+
Sbjct: 264 VDEEAGVAPNSASLTTGSEGILHGARTRLLQDRDGQIMESHSVSSGLDYAGVGPELAHLV 323
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAV--------IDKALEARREG 411
+ G V + A ++ EGI+PA ESAHA + A A G
Sbjct: 324 DTGRVTAVNVDDDAALTAFHRLSQMEGIIPALESAHAFGYLEVWSSGPDAPDAENADDLG 383
Query: 412 KEMVILFNLSGHGLLDLKGYEDYLDGKLEDYEPRDLPV 449
+ +V+ N+SG G D L+ +E+ RD+ +
Sbjct: 384 EYVVV--NVSGRGDKD-------LESAIEETYERDIDI 412
>sp|Q44685|TRPB_BUCAI TRYPTOPHAN SYNTHASE BETA CHAIN >gi|10038953|dbj|BAB12988.1|
(AP001118) tryptophan synthase beta chain [Buchnera sp.
APS]
Length = 388
Score = 125 bits (312), Expect = 8e-28
Identities = 115/394 (29%), Positives = 179/394 (45%), Gaps = 51/394 (12%)
Query: 60 ELVKQEISRERYIEIPGELRKLYSKI-GRPTPLFRATNLEKLLGTPARIYFKYEGATVTG 118
EL K +S ++ E + L GRPTPL NL K GT +IY K E G
Sbjct: 26 ELEKNFVSAQKDAEFQKKFFYLLQNYAGRPTPLTLCKNLTK--GTKTKIYLKREDLLHGG 83
Query: 119 SHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPY 178
+HK N L QA A + + ++ ETGAGQ G A ++A AL LK R+YM +++
Sbjct: 84 AHKTNQVLGQAMLAIRMKKKEIIAETGAGQHGVASAIACALFNLKCRIYMGIKDIKRQNT 143
Query: 179 RKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLG 237
M++ GAEV N G+L A +EA+ D +K+ Y +G
Sbjct: 144 NVFRMKLMGAEVI---------------SVKNGSGTLKDACNEALRDWSSSYKKSHYMIG 188
Query: 238 SVLNH------VLMHQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVL 289
+ V Q +IG E K+Q+ E E PD II C+GGGSN G+ F+ D
Sbjct: 189 TAAGPHPYPTIVREFQKMIGEETKKQILEKENKLPDSIIACIGGGSNAIGIFSDFIND-- 246
Query: 290 DGKSEYEFIAVEPKAAPTMTRGVYTYDYG-----DSAGLTPKLKMHTLGHR---YYVPPI 341
+ I VEP G++T +G G+ +K H + ++
Sbjct: 247 ----KVNLIGVEPAG-----YGIHTGKHGAPLKHGRTGIYFGMKSHLMQNKQGQIQESWS 297
Query: 342 HAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVI 401
+ GL + + P + L + K ++ E A + ++ EGI+PA ES+HA+ +
Sbjct: 298 ISAGLDFPSVGPEHAWLNSINRAKYVSITDEEAISAFQVLSRKEGIIPALESSHALAYAL 357
Query: 402 DKALEARREGKEMVILFNLSGHGLLDLKGYEDYL 435
L + E +++ NLS ++++K + Y+
Sbjct: 358 --KLMKKDPTIEQILIANLS---VVEIKIFLQYM 386
>sp|P54203|TRPB_PASMU TRYPTOPHAN SYNTHASE BETA CHAIN >gi|733125|gb|AAC43609.1| (U22344)
tryptophan synthase beta subunit [Pasteurella multocida]
Length = 403
Score = 123 bits (305), Expect = 5e-27
Identities = 124/421 (29%), Positives = 189/421 (44%), Gaps = 55/421 (13%)
Query: 42 PETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLL 101
PE P+ ++ L++ F E + +E ++++ L + GRPT L R NL +
Sbjct: 19 PEILMPV-LKNLEKAFVEAQ-QDPTFKETFLDL------LKNYAGRPTALTRCRNLTQ-- 68
Query: 102 GTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTA-LSLAGALL 160
G+ ++Y K E G+HK N L Q AK+ G R++ ETGAGQ G A +LA A+L
Sbjct: 69 GSKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATTALACAML 128
Query: 161 GLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAIS 220
G+ ++YM +++ MR+ GA V T V K SL A
Sbjct: 129 GMPCQIYMGAKDVERQSPNVFRMRLMGANV-------TAVTK--------GSASLKDACC 173
Query: 221 EAIEDVLKD-EKARYSLGSVLNH------VLMHQTVIGLEAKEQM--EEFEEPDVIIGCV 271
EA+ D ++ E Y LG+ V Q +IG E K+Q+ E PD +I V
Sbjct: 174 EAMRDWAENYEHTHYLLGTAAGPHPFPTIVREFQKIIGEETKQQILAREGRLPDAVIAAV 233
Query: 272 GGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDYG-----DSAGLTPK 326
GGGSN G+ F+++ + I VEP +G+ T +G + G+
Sbjct: 234 GGGSNAIGMFNDFIEE-----TSVRLIGVEPAG-----KGIATGQHGAPLGHGTTGIYFG 283
Query: 327 LK---MHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAK 383
+K M T + + GL + + P + L G + + E A A+
Sbjct: 284 MKAPLMQTPDGQIEESYSISAGLDFPSVGPQHAHLQAIGRAEYESITDDEALSAFEALAR 343
Query: 384 AEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLDGKLEDYE 443
EGI+PA ESAHA+ + L R KE +++ NLSG G D+ + L K +
Sbjct: 344 DEGIIPALESAHALAYAL--KLIQRHAEKEQLLVVNLSGRGDKDIFTVDRILSQKGVSHA 401
Query: 444 P 444
P
Sbjct: 402 P 402
>pir||T45257 probable tryptophan synthase (EC 4.2.1.20) beta chain [imported] -
Mycobacterium leprae (fragment)
>gi|4883463|emb|CAB43180.1| (AL049913) putative
tryptophan synthase beta chain [Mycobacterium leprae]
Length = 340
Score = 122 bits (303), Expect = 9e-27
Identities = 100/323 (30%), Positives = 148/323 (44%), Gaps = 54/323 (16%)
Query: 50 IEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYF 109
IE++ + +E V Q+ ++++ +L+ Y+ GRP+PL+ AT L + G+ RI+
Sbjct: 45 IEEVTAAYEKERVNQD-----FLDLLDKLQANYA--GRPSPLYEATRLSEYAGS-VRIFL 96
Query: 110 KYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMA 169
K E TGSHKIN L Q A++ G R++ ETGAGQ G A + A AL GL +YM
Sbjct: 97 KREDLNHTGSHKINNVLGQTLLAQRMGKTRVIAETGAGQHGVATATACALFGLDCVIYMG 156
Query: 170 RASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLK 228
++ MR+ GAEV + E G R LK+ AI++A D V
Sbjct: 157 ALDTARQALNVARMRLLGAEVV-----SVETGSRTLKD----------AINDAFRDWVTN 201
Query: 229 DEKARYSLGSVL------NHVLMHQTVIGLEAKEQM--EEFEEPDVIIGCVGGGSNFAGL 280
+ Y G+ V Q VIGLE + Q+ + PD + C+GGGSN G+
Sbjct: 202 ADNTYYCFGTASGPHPFPTMVRDLQRVIGLETRRQIQYQAGRLPDAVTACIGGGSNAIGI 261
Query: 281 AYPFVKD----------VLDGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMH 330
+ F+ D DG A P +G ++Y D G T ++ H
Sbjct: 262 FHAFLDDPGVRLVGFEAAGDGVETGRHAATLTGGLPGAFQGTFSYLLQDEDGQT--IESH 319
Query: 331 TLGHRYYVPPIHAGGLRYHGLAP 353
++ A GL Y G+ P
Sbjct: 320 SI----------AAGLDYPGVGP 332
>emb|CAA79516.1| (Z19090) tryptophan synthase; beta subunit [Vibrio metschnikovii]
Length = 391
Score = 120 bits (299), Expect = 3e-26
Identities = 111/363 (30%), Positives = 158/363 (42%), Gaps = 57/363 (15%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPT L NL K GT ++Y K E G+HK N L Q K+ G ++ ETG
Sbjct: 53 GRPTALTLTRNLTK--GTKTKLYLKREDLLHGGAHKTNEVLGQGLVGKRMGKSAIIAETG 110
Query: 146 AGQWGTALSLAGALLGLKVRVYM-ARASYQQKP--YRKTLMRIYGAEVFPSPSENTEVGK 202
AGQ G +LA AL+GLK R+ M A+ +Q P +R LM AE PS
Sbjct: 111 AGQHGVGSALASALVGLKCRIIMGAKNLERQSPNVFRMKLM----AESIPSSV------- 159
Query: 203 RFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNH------VLMHQTVIGLEAKE 256
+L +A++EA+ D E Y LG+ V Q +IG E K
Sbjct: 160 -----------TLKVAVNEALRDWSATETTHYYLGTAAGPHPYPTIVREFQRIIGEETKL 208
Query: 257 QM--EEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYT 314
Q+ E PD ++ C+GGGSN G+ F+ + + I +EP +G+ T
Sbjct: 209 QILAREGRLPDAVLACIGGGSNAIGMFADFIDE-----ANVRLIGIEPAG-----KGIDT 258
Query: 315 YDYGDSA---------GLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVK 365
+ +G G+ L + G + A GL + + P + L G
Sbjct: 259 HQHGAPLKHGKTGIFFGMKAPLMQDSYGQVEESYSVSA-GLDFPSVGPQHAHLNAIGRAN 317
Query: 366 PIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGL 425
+ E EA A+ EGI+ A ES+HA+ I A KE +++ NLSG G
Sbjct: 318 YESITDDEALEAFQSIARNEGIIAALESSHALAYAIKMA--RIDPDKEQLLVVNLSGRGD 375
Query: 426 LDL 428
D+
Sbjct: 376 KDI 378
>gb|AAG18887.1| (AE004991) tryptophan synthase beta chain; TrpB [Halobacterium sp.
NRC-1]
Length = 430
Score = 117 bits (291), Expect = 2e-25
Identities = 114/372 (30%), Positives = 161/372 (42%), Gaps = 55/372 (14%)
Query: 86 GRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 145
GRPTPL A L + G +Y K E G+HK+N AL Q AK G +R+V ETG
Sbjct: 62 GRPTPLTHAPTLSQRHGVD--VYLKREDLLHGGAHKLNNALGQVLLAKYMGKDRIVAETG 119
Query: 146 AGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFL 205
AGQ GTA ++A A L + +YM R ++ MR++ A+V P VG L
Sbjct: 120 AGQHGTATAMACAALEMPCEIYMGRTDVNRQRPNVFRMRLHDADVNP-----VTVGSGTL 174
Query: 206 KEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVL------NHVLMHQTVIGLEAKEQM 258
KE AI+E + D Y +GSV+ + V Q +I E + Q
Sbjct: 175 KE----------AINETMRDWATNVADTHYVIGSVVGPHPFPSMVRDFQAIISEELRAQS 224
Query: 259 EE--FEEPDVIIGCVGGGSNFAGLAYPFVKDVL---------DGKSEYEFIAVEPKA--- 304
E E P +I C GGGSN G FV + + + +AVE
Sbjct: 225 REQLGELPAAVIACAGGGSNTMGAFGAFVGSASLPGAPAGTHEPAPDVDLLAVEAGGSRL 284
Query: 305 --------APTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLS 356
AP + + T G G KL G + A GL Y G+ P L+
Sbjct: 285 GVDDDAGYAPN-SASLSTGTEGVLHGARTKLLQTETGQIVESHSVSA-GLDYAGVGPELA 342
Query: 357 VLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVI 416
L++ G + P A ++ EG++PA E++HAV A+ + +G V+
Sbjct: 343 HLVDTGRITPTNVDDDAALAAFHRLSRDEGVIPALETSHAVAAL------DQYDGDGPVV 396
Query: 417 LFNLSGHGLLDL 428
+ N+SG G DL
Sbjct: 397 V-NVSGRGDKDL 407
>dbj|BAA14796.1| (D90764) Tryptophan synthase b chain (EC 4.2.1.20). [Escherichia
coli]
Length = 344
Score = 115 bits (285), Expect = 1e-24
Identities = 92/251 (36%), Positives = 120/251 (47%), Gaps = 38/251 (15%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 46 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 101
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 102 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 160
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGSVLNH------VLMHQTV 249
G LK+ A +EA+ D E A Y LG+ V Q +
Sbjct: 161 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 206
Query: 250 IGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPT 307
IG E K Q+ E E PD +I CVGGGSN G+ F+ + G I VEP
Sbjct: 207 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-----LIGVEPGG--- 258
Query: 308 MTRGVYTYDYG 318
G+ T ++G
Sbjct: 259 --HGIETGEHG 267
>pir||T42090 tryptophan synthase (EC 4.2.1.20) - fission yeast
(Schizosaccharomyces pombe) (fragment)
>gi|1749434|dbj|BAA13775.1| (D89113) similar to
Saccharomyces cerevisiae triptophan synthase, SWISS-PROT
Accession Number P00931 [Schizosaccharomyces pombe]
Length = 420
Score = 114 bits (283), Expect = 2e-24
Identities = 115/357 (32%), Positives = 164/357 (45%), Gaps = 43/357 (12%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
E R Y +GRP+ L A L + G A I+ K E GSHKIN + Q AK+ G
Sbjct: 78 EFRSYYEYMGRPSALDYAKRLTEYCGG-AHIWLKREDLNHGGSHKINNCIGQILLAKRLG 136
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQK-----PYRKTLMRIYGAEVF 191
R++ ETGAGQ G A ++ A K+ M ++ QK +R+ GAEV
Sbjct: 137 KNRIIAETGAGQHGVATAICPA----KIWYEMYYPTWVQKIVVVQALNVFRIRLLGAEVV 192
Query: 192 PSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSVLNH------VL 244
P S G + L++ A++EA++ V + + Y GS + V
Sbjct: 193 PLTS-----GTQTLRD----------AVNEALKAWVEQIDTTHYLTGSAIGPHPFPTIVK 237
Query: 245 MHQTVIGLEAKEQMEEFEE--PDVIIGCVGGGSNFAGLAYPFV--KDVLDGKSEYEFIAV 300
Q+VIG E K QM+E + PD ++ CVGGGSN G+ PF K V+ E V
Sbjct: 238 TFQSVIGEETKAQMQEKRKKLPDAVVACVGGGSNSIGMFSPFKADKSVMMLGCEAGGDGV 297
Query: 301 E-PKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLI 359
+ PK + T+T G G G+ + G I A GL Y G+ P LS L
Sbjct: 298 DTPKHSATLTMG----KVGVFHGVRTYVLQREDGQIQDTHSISA-GLDYPGVGPELSELK 352
Query: 360 NHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVI 416
+ IA + E EGI+PA ES+HAV ++ A + ++ K++VI
Sbjct: 353 YTNRAEFIAVTDAQCLEGFRALCHLEGIIPALESSHAVYGGMELAKKLPKD-KDIVI 408
>emb|CAB42885.2| (AJ239040) tryptophan synthase beta-subunit [Prevotella albensis]
Length = 254
Score = 109 bits (269), Expect = 8e-23
Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 33/237 (13%)
Query: 61 LVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSH 120
+++ E ++ Y+++ L +GRP+PL+ A + G ++Y K E TG+H
Sbjct: 27 IIESEDFQKEYMQL------LRDYVGRPSPLYYAKRMSDRYG--CQLYLKREDLNHTGAH 78
Query: 121 KINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRK 180
KIN + Q AKK G R++ ETGAGQ G A + AL+ ++ ++M +++
Sbjct: 79 KINNTVGQILMAKKMGKTRIIAETGAGQHGVATATVCALMDMECEIFMGATDVERQHTNV 138
Query: 181 TLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEKARYSLGSV 239
M++ GA+V P + N +L A SEAI D E Y +GS
Sbjct: 139 ERMKMLGAKVHPVRTGNM---------------TLSDACSEAIRDWCCHPENTFYIVGST 183
Query: 240 L------NHVLMHQTVIGLEAKEQMEE---FEEPDVIIGCVGGGSNFAGLAYPFVKD 287
+ + V Q++I E K Q++E + PD +I CVGGGSN AG Y ++ D
Sbjct: 184 MGPHPYPDIVAKMQSIISKELKGQLQEKIGRDYPDYLIACVGGGSNAAGTIYHYIDD 240
>gb|AAD17312.1| (AF121272) putative tryptophan synthase beta subunit precursor
[Gracilaria gracilis]
Length = 339
Score = 99.1 bits (243), Expect = 9e-20
Identities = 81/230 (35%), Positives = 110/230 (47%), Gaps = 32/230 (13%)
Query: 61 LVKQEISRERYIEIPGELRKL----YSKIGRPTPLFRATNLEKLL----GTPARIYFKYE 112
L + E S R E P L++L +GRP+PL+ A L G+ +IY K E
Sbjct: 125 LQELEASYHRIKEDPEFLQELGGLLRDYVGRPSPLYFAERLTSRYARADGSGPQIYLKRE 184
Query: 113 GATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARAS 172
TG+HKIN +LAQ AK+ G R++ ETGAGQ G A + A GL+ VYM
Sbjct: 185 DLNHTGAHKINNSLAQVLLAKRLGKTRIIAETGAGQHGVATATVCARFGLQCIVYMGAKD 244
Query: 173 YQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIED-VLKDEK 231
+++ MR+ GAEV P S + +L A+SEAI D V +
Sbjct: 245 MERQALNVFRMRLLGAEVRPVTSGS---------------ATLTNALSEAIRDWVTYPIE 289
Query: 232 ARYSLGSVLNH------VLMHQTVIGLEAKEQMEE--FEEPDVIIGCVGG 273
Y +GSV V Q IG E +EQ E +PD+++ CVGG
Sbjct: 290 THYIVGSVAGPHPYPMIVRDFQACIGRETREQALEKWGGKPDILLACVGG 339
>gb|AAG14886.1|AF293320_2 (AF293320) tryptophan synthase beta subunit [Escherichia coli]
Length = 190
Score = 88.9 bits (217), Expect = 1e-16
Identities = 64/163 (39%), Positives = 83/163 (50%), Gaps = 20/163 (12%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT A +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNATLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGS 238
G LK+ A +EA+ D E A Y LG+
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGT 190
>gb|AAG14782.1|AF293268_2 (AF293268) tryptophan synthase beta subunit [Escherichia coli]
>gi|10186334|gb|AAG14786.1|AF293270_2 (AF293270)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186337|gb|AAG14788.1|AF293271_2 (AF293271)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186340|gb|AAG14790.1|AF293272_2 (AF293272)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186343|gb|AAG14792.1|AF293273_2 (AF293273)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186346|gb|AAG14794.1|AF293274_2 (AF293274)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186349|gb|AAG14796.1|AF293275_2 (AF293275)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186352|gb|AAG14798.1|AF293276_2 (AF293276)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186358|gb|AAG14802.1|AF293278_2 (AF293278)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186361|gb|AAG14804.1|AF293279_2 (AF293279)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186364|gb|AAG14806.1|AF293280_2 (AF293280)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186367|gb|AAG14808.1|AF293281_2 (AF293281)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186370|gb|AAG14810.1|AF293282_2 (AF293282)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186373|gb|AAG14812.1|AF293283_2 (AF293283)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186376|gb|AAG14814.1|AF293284_2 (AF293284)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186379|gb|AAG14816.1|AF293285_2 (AF293285)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186382|gb|AAG14818.1|AF293286_2 (AF293286)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186385|gb|AAG14820.1|AF293287_2 (AF293287)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186388|gb|AAG14822.1|AF293288_2 (AF293288)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186391|gb|AAG14824.1|AF293289_2 (AF293289)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186394|gb|AAG14826.1|AF293290_2 (AF293290)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186397|gb|AAG14828.1|AF293291_2 (AF293291)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186400|gb|AAG14830.1|AF293292_2 (AF293292)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186403|gb|AAG14832.1|AF293293_2 (AF293293)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186406|gb|AAG14834.1|AF293294_2 (AF293294)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186409|gb|AAG14836.1|AF293295_2 (AF293295)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186412|gb|AAG14838.1|AF293296_2 (AF293296)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186415|gb|AAG14840.1|AF293297_2 (AF293297)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186418|gb|AAG14842.1|AF293298_2 (AF293298)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186421|gb|AAG14844.1|AF293299_2 (AF293299)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186424|gb|AAG14846.1|AF293300_2 (AF293300)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186427|gb|AAG14848.1|AF293301_2 (AF293301)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186430|gb|AAG14850.1|AF293302_2 (AF293302)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186433|gb|AAG14852.1|AF293303_2 (AF293303)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186436|gb|AAG14854.1|AF293304_2 (AF293304)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186439|gb|AAG14856.1|AF293305_2 (AF293305)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186442|gb|AAG14858.1|AF293306_2 (AF293306)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186445|gb|AAG14860.1|AF293307_2 (AF293307)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186448|gb|AAG14862.1|AF293308_2 (AF293308)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186454|gb|AAG14866.1|AF293310_2 (AF293310)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186457|gb|AAG14868.1|AF293311_2 (AF293311)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186460|gb|AAG14870.1|AF293312_2 (AF293312)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186463|gb|AAG14872.1|AF293313_2 (AF293313)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186475|gb|AAG14880.1|AF293317_2 (AF293317)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186478|gb|AAG14882.1|AF293318_2 (AF293318)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186481|gb|AAG14884.1|AF293319_2 (AF293319)
tryptophan synthase beta subunit [Escherichia coli]
Length = 190
Score = 87.4 bits (213), Expect = 3e-16
Identities = 63/163 (38%), Positives = 82/163 (49%), Gaps = 20/163 (12%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGS 238
G LK+ A +EA+ D E A Y LG+
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGT 190
>gb|AAG14874.1|AF293314_2 (AF293314) tryptophan synthase beta subunit [Escherichia coli]
>gi|10186469|gb|AAG14876.1|AF293315_2 (AF293315)
tryptophan synthase beta subunit [Escherichia coli]
>gi|10186472|gb|AAG14878.1|AF293316_2 (AF293316)
tryptophan synthase beta subunit [Escherichia coli]
Length = 190
Score = 87.4 bits (213), Expect = 3e-16
Identities = 63/163 (38%), Positives = 82/163 (49%), Gaps = 20/163 (12%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGS 238
G LK+ A +EA+ D E A Y LG+
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGT 190
>gb|AAG14864.1|AF293309_2 (AF293309) tryptophan synthase beta subunit [Escherichia coli]
Length = 190
Score = 87.0 bits (212), Expect = 4e-16
Identities = 63/163 (38%), Positives = 82/163 (49%), Gaps = 20/163 (12%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKQMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSE 196
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P S
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS- 161
Query: 197 NTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKD-EKARYSLGS 238
G LK+ A +EA+ D E A Y LG+
Sbjct: 162 ----GSATLKD----------ACNEALRDWSGSYETAHYMLGT 190
>gb|AAG14784.1|AF293269_2 (AF293269) tryptophan synthase beta subunit [Escherichia coli]
Length = 190
Score = 85.8 bits (209), Expect = 9e-16
Identities = 50/116 (43%), Positives = 65/116 (55%), Gaps = 4/116 (3%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N+ GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFP 192
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
>gb|AAG14800.1|AF293277_2 (AF293277) tryptophan synthase beta subunit [Escherichia coli]
Length = 190
Score = 84.7 bits (206), Expect = 2e-15
Identities = 50/116 (43%), Positives = 64/116 (55%), Gaps = 4/116 (3%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
+L K Y+ GRPT L + N GT +Y K E G+HK N L QA AK+ G
Sbjct: 47 DLLKNYA--GRPTALTKCQNTTA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFP 192
++ ETGAGQ G A +LA ALLGLK R+YM +++ MR+ GAEV P
Sbjct: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
>gb|AAD04365.1| (AF084897) mutant tryptophan synthase [Neurospora crassa]
Length = 133
Score = 70.6 bits (170), Expect = 3e-11
Identities = 39/92 (42%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 77 ELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQG 136
E R Y +GRP L +A L + G A I+ K EG TGSHKIN AL Q A++ G
Sbjct: 41 EYRSYYPWMGRPGQLHKAERLTEYAGG-ANIWLKREGLNHTGSHKINNALGQLLLARRLG 99
Query: 137 IERLVTETGAGQWGTALSLAGALLGLKVRVYM 168
++++ ETGAGQ G A + A G++ V+M
Sbjct: 100 KKKIIAETGAGQHGVATATVCAKFGMECTVFM 131
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.139 0.404
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 177949781
Number of Sequences: 2977
Number of extensions: 7955201
Number of successful extensions: 21288
Number of sequences better than 1.0e-10: 108
Number of HSP's better than 0.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 20826
Number of HSP's gapped (non-prelim): 124
length of query: 451
length of database: 189,106,746
effective HSP length: 56
effective length of query: 395
effective length of database: 155,591,474
effective search space: 61458632230
effective search space used: 61458632230
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)