BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1971 (PAB1971) DE:DOLICHYL-PHOSPHATE MANNOSE SYNTHASE (287 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||D75177 dolichyl-phosphate mannose synthase PAB1971 - Pyroco... 562 e-159 pir||A71037 hypothetical protein PH1585 - Pyrococcus horikoshii ... 447 e-125 sp|Q58619|YC22_METJA HYPOTHETICAL PROTEIN MJ1222 >gi|2128734|pir... 215 6e-55 pir||G69047 conserved hypothetical protein MTH136 - Methanobacte... 176 2e-43 pir||H70561 probable transferase - Mycobacterium tuberculosis (s... 144 1e-33 emb|CAA18811.1| (AL023093) putative transferase [Mycobacterium l... 136 4e-31 pir||G69148 dolichyl-phosphate mannose synthase related protein ... 129 3e-29 pir||A75176 dolichyl-phosphate mannose synthase related protein ... 129 3e-29 pir||D69148 dolichyl-phosphate mannose synthase related protein ... 127 1e-28 pir||D71038 hypothetical protein PH1596 - Pyrococcus horikoshii ... 123 3e-27 gi|11497660 dolichol-P-glucose synthetase, putative [Archaeoglob... 118 1e-25 gi|11497999 glycosyltransferase, putative [Archaeoglobus fulgidu... 109 5e-23 gi|11497940 dolichol-P-glucose synthetase, putative [Archaeoglob... 105 7e-22 emb|CAC11300.1| (AL445063) conserved hypothetical protein [Therm... 98 9e-20 pir||B71154 hypothetical protein PH0433 - Pyrococcus horikoshii ... 97 2e-19 emb|CAC15463.1| (AJ294477) putative polyprenol phosphate mannosy... 94 1e-18 dbj|BAA19644.1| (AB002668) unnamed protein product [Actinobacill... 94 2e-18 pir||E69142 mannosyltransferase - Methanobacterium thermoautotro... 94 2e-18 pir||F75058 dolichol-p-glucose synthetase PAB1411 - Pyrococcus a... 93 3e-18 pir||B75100 glycosyltransferase PAB1587 - Pyrococcus abyssi (str... 93 4e-18 pir||C69052 conserved hypothetical protein MTH1392 - Methanobact... 91 2e-17 pir||E82657 dolichyl-phosphate mannose synthase related protein ... 87 2e-16 gb|AAK43334.1| Dolichol-phosphate mannosyltransferase [Sulfolobu... 86 4e-16 gb|AAC35924.1| (AF071085) putative glycosyl transferase [Enteroc... 85 7e-16 gb|AAD30975.1|AF121895_1 (AF121895) dolichol-phosphate-mannose s... 82 6e-15 gb|AAC98797.1| (AF007875) dolichol monophosphate mannose synthas... 82 8e-15 gi|6753670 dolichol-phosphate (beta-D) mannosyltransferase 1 [Mu... 82 8e-15 pir||G75191 dolichol-phosphate mannosyltransferase PAB2307 - Pyr... 82 8e-15 emb|CAB11300.1| (Z98604) hypothetical protein MLCB2052.02 [Mycob... 81 1e-14 gi|4503363 dolichyl-phosphate mannosyltransferase polypeptide 1;... 80 3e-14 gb|AAF80640.1|AC069251_33 (AC069251) F2D10.6 [Arabidopsis thaliana] 80 3e-14 pir||B70945 hypothetical protein Rv2051c - Mycobacterium tubercu... 80 3e-14 gb|AAG32629.1|AF102883_1 (AF102883) mannose phospho-dolichol syn... 80 4e-14 gb|AAF53817.1| (AE003663) CG10166 gene product [Drosophila melan... 79 7e-14 sp|Q57964|Y544_METJA HYPOTHETICAL PROTEIN MJ0544 >gi|2127875|pir... 78 9e-14 emb|CAB61668.1| (AL133213) putative glycosyl transferase. [Strep... 76 4e-13 pir||H71223 probable dolichol-phosphate mannosyltransferase - Py... 76 6e-13 pir||B75440 rfbJ protein/conserved hypothetical protein - Deinoc... 75 8e-13 gb|AAG19457.1| (AE005038) glycosyl transferase-like; Gtl [Haloba... 75 1e-12 pir||T38633 dolichol monophosphate mannose synthase - fission ye... 71 1e-11 gb|AAD01952.1| (AF033015) unknown [Listeria monocytogenes] 71 1e-11 pir||T40534 dolichyl-phosphate beta-gluco syltransferase - fissi... 71 1e-11 gb|AAG19351.1| (AE005030) galactosyltransferase homolog; Gst [Ha... 70 3e-11 gi|7019323 dolichyl phosphate glucosyltransferase; Alg5, S. cere... 70 3e-11 gb|AAG09682.1|AF183413_1 (AF183413) dolichyl-phosphate beta-gluc... 70 3e-11 gi|6325029 UDP-glucose:dolichyl-phosphate glucosyltransferase; A... 69 6e-11 >pir||D75177 dolichyl-phosphate mannose synthase PAB1971 - Pyrococcus abyssi (strain Orsay) >gi|5458009|emb|CAB49499.1| (AJ248284) DOLICHYL-PHOSPHATE MANNOSE SYNTHASE [Pyrococcus abyssi] Length = 287 Score = 562 bits (1433), Expect = e-159 Identities = 287/287 (100%), Positives = 287/287 (100%) Query: 1 MRLDKVRVENENDKELIAFINSLGIEINENALPIIGRYYVEILGTRYEAESFDELKSLVG 60 MRLDKVRVENENDKELIAFINSLGIEINENALPIIGRYYVEILGTRYEAESFDELKSLVG Sbjct: 1 MRLDKVRVENENDKELIAFINSLGIEINENALPIIGRYYVEILGTRYEAESFDELKSLVG 60 Query: 61 RLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHI 120 RLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHI Sbjct: 61 RLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHI 120 Query: 121 INRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKG 180 INRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKG Sbjct: 121 INRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKG 180 Query: 181 NLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEII 240 NLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEII Sbjct: 181 NLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEII 240 Query: 241 VEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFVDLFRR 287 VEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFVDLFRR Sbjct: 241 VEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFVDLFRR 287 >pir||A71037 hypothetical protein PH1585 - Pyrococcus horikoshii >gi|3258014|dbj|BAA30697.1| (AP000006) 313aa long hypothetical protein [Pyrococcus horikoshii] Length = 313 Score = 447 bits (1138), Expect = e-125 Identities = 213/287 (74%), Positives = 254/287 (88%) Query: 1 MRLDKVRVENENDKELIAFINSLGIEINENALPIIGRYYVEILGTRYEAESFDELKSLVG 60 ++L+ RV + D EL++F+ SLGIE+NE ALPIIGRYY+ IL Y +ES+D L+ ++ Sbjct: 27 VKLESARVSSREDSELLSFVKSLGIEVNEKALPIIGRYYIRILDVEYTSESWDGLREIIN 86 Query: 61 RLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHI 120 +L KTYIVMPAYNEEKTIG VLDSLL+VF NIIVVDDGS+D+TREIAKSKGVHV+SHI Sbjct: 87 KLRKTYIVMPAYNEEKTIGSVLDSLLKVFKPNNIIVVDDGSKDKTREIAKSKGVHVISHI 146 Query: 121 INRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKG 180 INRGLGGALGTGI YA+ +GAEI+VTFDADGQH++EDAL+VIKPV EG+ DLAIGSRFKG Sbjct: 147 INRGLGGALGTGIYYALMRGAEIIVTFDADGQHLLEDALKVIKPVVEGRADLAIGSRFKG 206 Query: 181 NLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEII 240 ++ QMPLVKR+GNI LN ITA+FA RY++D+QSGLRAFSR CAS++KITCDGYAVSSEII Sbjct: 207 DIGQMPLVKRIGNIVLNTITAVFAMRYVTDSQSGLRAFSRACASKIKITCDGYAVSSEII 266 Query: 241 VEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFVDLFRR 287 VEASR KC+IVE+PI AVYTEYSMKKGTNV+EGIKIA+NL +D+FRR Sbjct: 267 VEASRGKCKIVEVPIKAVYTEYSMKKGTNVMEGIKIAINLLLDIFRR 313 >sp|Q58619|YC22_METJA HYPOTHETICAL PROTEIN MJ1222 >gi|2128734|pir||E64452 conserved hypothetical protein MJ1222 - Methanococcus jannaschii >gi|1591853|gb|AAB99226.1| (U67563) dolichol-P-glucose synthetase isolog [Methanococcus jannaschii] Length = 243 Score = 215 bits (541), Expect = 6e-55 Identities = 113/221 (51%), Positives = 151/221 (68%), Gaps = 5/221 (2%) Query: 66 YIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGL 125 ++V+PA+NEEK IG+ L +L + +NI+VVDDGS D+T EIAK +GV V HI+NRGL Sbjct: 20 FVVVPAFNEEKMIGETLKNLKKE-GYKNIVVVDDGSMDKTSEIAKKEGVIVCRHILNRGL 78 Query: 126 GGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF--KGNLN 183 GGALGTGI+ A+ +I++TFDADGQH +D +V+KPV D+AIGSR K L Sbjct: 79 GGALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLFEGYDMAIGSRMMDKNELK 138 Query: 184 QMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV--KITCDGYAVSSEIIV 241 MPLVKR+GN LN IT + +++D+QSGLRAFS A ++ + D Y VSSE I+ Sbjct: 139 NMPLVKRIGNFGLNFITYLMGGYFVTDSQSGLRAFSYEAAKKIIGDLKSDRYEVSSEFII 198 Query: 242 EASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFV 282 A + ++ E+PI +YTEYSM +GTNVI G KI L + Sbjct: 199 LAKKHGLKLKEVPIKTIYTEYSMSRGTNVITGFKILFKLIM 239 >pir||G69047 conserved hypothetical protein MTH136 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621176|gb|AAB84642.1| (AE000802) dolichyl-phosphate mannose synthase [Methanobacterium thermoautotrophicum] Length = 220 Score = 176 bits (442), Expect = 2e-43 Identities = 99/206 (48%), Positives = 136/206 (65%), Gaps = 10/206 (4%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREI-----AKSKGVHVVSHII 121 +V+P YNEEKT+ V++SLL R +I VDDGSRD T EI ++ G+ V +H+I Sbjct: 14 VVVPVYNEEKTVAGVIESLLDRGYR--VIAVDDGSRDSTPEILAGIASERDGLSVYTHVI 71 Query: 122 NRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGN 181 NRGLG AL TG+R AV +GA +VTFDADGQH +D VI+P+ +G+ D+ IGSR + Sbjct: 72 NRGLGTALRTGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEADVVIGSR---D 128 Query: 182 LNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIV 241 ++MPL + +GN +NL+T +F +SD+QSGLRAF+ AS + I GY VSSEII Sbjct: 129 FSEMPLSRSLGNTLMNLLTLLFYGCRVSDSQSGLRAFTARAASVIDIKSRGYGVSSEIIG 188 Query: 242 EASRKKCRIVEIPITAVYTEYSMKKG 267 E R R+ E+ I +YT ++ KG Sbjct: 189 EIHRNGLRMREVTIKTIYTPETISKG 214 >pir||H70561 probable transferase - Mycobacterium tuberculosis (strain H37RV) >gi|2105063|emb|CAB08827.1| (Z95436) hypothetical protein Rv3631 [Mycobacterium tuberculosis] Length = 241 Score = 144 bits (360), Expect = 1e-33 Identities = 80/223 (35%), Positives = 129/223 (56%), Gaps = 8/223 (3%) Query: 66 YIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGL 125 ++V+PA+NE IG V+ + VF ++++ VDDGS D T +IA+ G H+V H IN G Sbjct: 15 WVVIPAFNEAAVIGKVVTDVRSVF--DHVVCVDDGSTDGTGDIARRSGAHLVRHPINLGQ 72 Query: 126 GGALGTGIRYAVYK-GAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF-----K 179 G A+ TGI YA + GA++ TFD DGQH V+D ++ + G D+ IG+RF K Sbjct: 73 GAAIQTGIEYARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGAGDVDVVIGTRFGRPVGK 132 Query: 180 GNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEI 239 + ++ PL+KR+ ++ ++DT +GLR F++ A + IT G + ++E Sbjct: 133 ASASRPPLMKRIVLQTGARLSRRGRRLGLTDTNNGLRVFNKTVADGLNITMSGMSHATEF 192 Query: 240 IVEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFV 282 I+ + R+ E P+ +YTEYS KG ++ G+ I + F+ Sbjct: 193 IMLIAENHWRVAEEPVEVLYTEYSKSKGQPLLNGVNIIFDGFL 235 >emb|CAA18811.1| (AL023093) putative transferase [Mycobacterium leprae] Length = 239 Score = 136 bits (338), Expect = 4e-31 Identities = 81/228 (35%), Positives = 131/228 (56%), Gaps = 16/228 (7%) Query: 66 YIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGL 125 +IV+PA+NE IG+V+ + VF ++++ VDDGS D T EIA G H+V H +N G Sbjct: 11 WIVIPAFNEAAIIGEVVTDVRAVF--DHVVCVDDGSADGTGEIALRAGAHLVRHPVNLGQ 68 Query: 126 GGALGTGIRYAVYK-GAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLN- 183 G A+ TG+ YA + A++ TFDADGQH V+D ++ + D+ IG+RF G L+ Sbjct: 69 GAAIQTGVEYARRQPAAQVFATFDADGQHRVKDLAALVDRLGAHDVDVVIGTRF-GRLDG 127 Query: 184 -QMPLVKRVGNIALNLITAIFAFRY--------ISDTQSGLRAFSRNCASRVKITCDGYA 234 ++P++K G L + A R ++DT +GLR F++ A + IT G + Sbjct: 128 GRLPILK--GPPFLKRVVLRTAARLSRRGRRLGLTDTNNGLRVFNKKVADGLDITMTGMS 185 Query: 235 VSSEIIVEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFV 282 ++E ++ + R+ E+P+ +YTEYS KG ++ G+ I + F+ Sbjct: 186 HANEFVMLIADNHWRVDEVPVEVLYTEYSKSKGQPLLNGVNIIFDGFL 233 >pir||G69148 dolichyl-phosphate mannose synthase related protein 1 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621438|gb|AAB84883.1| (AE000823) dolichyl-phosphate mannose synthase related protein [Methanobacterium thermoautotrophicum] Length = 248 Score = 129 bits (322), Expect = 3e-29 Identities = 86/226 (38%), Positives = 121/226 (53%), Gaps = 8/226 (3%) Query: 60 GRLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSH 119 G M+ V+PA+NEE+T+ V+ L ++I+VDDGS DRT + + G V+SH Sbjct: 20 GVAMRVVTVIPAFNEERTVESVVRGALE---HGDVILVDDGSTDRTAALGEEAGARVISH 76 Query: 120 IINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF- 178 N G G AL TGIR A+ +++V DADGQH + V G D IGSRF Sbjct: 77 PKNLGKGAALKTGIREALGGDYDVIVFMDADGQHDPSLIPELASAVNGG--DFIIGSRFI 134 Query: 179 KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV-KITCDGYAVSS 237 + N + MPL +++ N I + I+D+QSG RA S A + +I D Y S Sbjct: 135 RNNHDSMPLHRQLSNRITTWILRLATGYRITDSQSGFRAISARYAHLILEIPYDDYVYES 194 Query: 238 EIIVEASRKKCRIVEIPITAVYTEYSMKKGT-NVIEGIKIALNLFV 282 E I E SR + RI E+PIT Y + G +V++ I+ + LFV Sbjct: 195 EAICETSRHRLRIAEVPITCTYGDEKSYIGVGDVLQYIRFIVRLFV 240 >pir||A75176 dolichyl-phosphate mannose synthase related protein PAB1981 - Pyrococcus abyssi (strain Orsay) >gi|5457998|emb|CAB49488.1| (AJ248284) DOLICHYL-PHOSPHATE MANNOSE SYNTHASE RELATED PROTEIN [Pyrococcus abyssi] Length = 211 Score = 129 bits (322), Expect = 3e-29 Identities = 77/205 (37%), Positives = 117/205 (56%), Gaps = 11/205 (5%) Query: 63 MKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIIN 122 MK +++PAYNEEK IG VL + +IVVDDGS+D T ++AK GV V+ N Sbjct: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFV--NEVIVVDDGSKDNTADVAKRFGVRVIRLPEN 58 Query: 123 RGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNL 182 RG G A+ GI++A KG +I+V DADGQH ++ ++I P+ +G D IG R Sbjct: 59 RGKGAAMREGIKHA--KG-DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVI-KA 114 Query: 183 NQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVE 242 + PLV+++ N + + + DTQSG RA R I + Y V +E++++ Sbjct: 115 GKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLP--DIESERYEVETEVLIK 172 Query: 243 ASRKKCRIVEIPITAVYTEYSMKKG 267 ++K RIVE+P++ T Y ++ G Sbjct: 173 VAKKGARIVEVPVS---TRYDVETG 194 >pir||D69148 dolichyl-phosphate mannose synthase related protein 2 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621435|gb|AAB84880.1| (AE000823) dolichyl-phosphate mannose synthase related protein [Methanobacterium thermoautotrophicum] Length = 291 Score = 127 bits (316), Expect = 1e-28 Identities = 80/223 (35%), Positives = 117/223 (51%), Gaps = 7/223 (3%) Query: 63 MKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIIN 122 M+ V+PA+NEE IG V+ LL + +IVVDDGS DRT +A+ G V+ H N Sbjct: 1 MRIVAVIPAFNEEVAIGSVV--LLTGEHVDEVIVVDDGSADRTAHVAEMAGARVIRHHRN 58 Query: 123 RGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF-KGN 181 G G AL TG A A+++VT DAD QH + ++++P+ G+ D+ GSR+ G Sbjct: 59 LGKGAALKTGFEAA---DADVIVTLDADAQHNPAEIPKLVEPILRGEADVVNGSRYLHGR 115 Query: 182 LNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIV 241 P +RVG L+ T I I+DTQSG RAFS + G+ V SE++ Sbjct: 116 DENTPRYRRVGQKILDRATNISTGLDITDTQSGFRAFSSASIPHFRFRDPGFVVESEMLA 175 Query: 242 EASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFVDL 284 +A+ RIVE+ + Y + + G+ + L + DL Sbjct: 176 DAAEAGLRIVEVEVGVRY-DVDGSTRNPISHGVSVLLRIIGDL 217 >pir||D71038 hypothetical protein PH1596 - Pyrococcus horikoshii >gi|3258025|dbj|BAA30708.1| (AP000006) 215aa long hypothetical protein [Pyrococcus horikoshii] Length = 215 Score = 123 bits (305), Expect = 3e-27 Identities = 72/204 (35%), Positives = 114/204 (55%), Gaps = 11/204 (5%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINR 123 K +++PAYNEE+ IG+VL + + +IVVDDGS D T ++A G V+ N Sbjct: 6 KISVIIPAYNEERRIGNVLKGIPDFV--DEVIVVDDGSSDGTSKVAMELGATVIRLNKNS 63 Query: 124 GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLN 183 G G A+ G++ + +I+V DADGQH ++ R++KP+ EG+ DL IG R Sbjct: 64 GKGAAMREGLKIST---GDIIVFMDADGQHNPKEIYRLVKPIVEGRADLVIGRRII-TRG 119 Query: 184 QMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVEA 243 + P+ +++ N + + + I DTQSG RA R I D Y V +E++++A Sbjct: 120 KRPMSRKISNFITTRLITLKTRKKILDTQSGFRAIRREFVP--VIESDRYEVETEVLIKA 177 Query: 244 SRKKCRIVEIPITAVYTEYSMKKG 267 +K RI+E+PI+ T Y ++ G Sbjct: 178 IKKGARILEVPIS---TRYDVETG 198 >gi|11497660 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] >gi|7483292|pir||G69254 dolichol-P-glucose synthetase homolog - Archaeoglobus fulgidus >gi|2650613|gb|AAB91190.1| (AE001104) dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] Length = 369 Score = 118 bits (292), Expect = 1e-25 Identities = 74/197 (37%), Positives = 114/197 (57%), Gaps = 9/197 (4%) Query: 63 MKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIIN 122 MK IV+P +E+ +I V+ L + + IIVVDD S DRT EIA+ G V+ + Sbjct: 1 MKVSIVLPTKDEQNSIEKVVRDCLSLGFEKEIIVVDD-SADRTPEIAEKLGCKVIRGV-- 57 Query: 123 RGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNL 182 +G G A G R++ +I+V DADG + + R+I+P+ +G+ DL IGSRFKG + Sbjct: 58 KGYGRAFLEGFRHS---SGDIIVMLDADGSYDALEIPRLIEPIVKGEADLVIGSRFKGKI 114 Query: 183 --NQMPLVKR-VGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEI 239 MP R VGN L +T + +SD SG+RA ++ +++ C G ++E+ Sbjct: 115 MPKAMPWHHRYVGNPVLTKLTNLLFKTKLSDVHSGMRALRKDALAKIDPVCPGMEFATEL 174 Query: 240 IVEASRKKCRIVEIPIT 256 +++A+ K RIVE+PIT Sbjct: 175 VLKAAIKGLRIVEVPIT 191 >gi|11497999 glycosyltransferase, putative [Archaeoglobus fulgidus] >gi|7445538|pir||C69298 glycosyltransferase homolog - Archaeoglobus fulgidus >gi|2650247|gb|AAB90850.1| (AE001078) glycosyltransferase, putative [Archaeoglobus fulgidus] Length = 305 Score = 109 bits (269), Expect = 5e-23 Identities = 74/224 (33%), Positives = 118/224 (52%), Gaps = 16/224 (7%) Query: 63 MKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIIN 122 M +V+P NEE+ IG+V++ + R ++V+D S+DRTREIA+ KG VV Sbjct: 1 MDVTVVIPTLNEEEAIGEVVEGFAKRGFR--VLVIDGNSKDRTREIAREKGAEVVIQS-G 57 Query: 123 RGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF---- 178 +G G A+ ++I+V D DG ++ E+ R+++P+ EG D IG+RF Sbjct: 58 KGKGQAVAEAFEIV---DSDILVLVDGDGTYLPEEVYRLLEPIKEGGADHVIGNRFASFE 114 Query: 179 KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSE 238 KG ++ L+ GN LN+ + + D SG RA + V++T G+ V +E Sbjct: 115 KGAFTRLNLI---GNKLLNMFFRLAYGVELRDILSGYRALKKEVYKSVELTKPGFEVETE 171 Query: 239 IIVEASRKKCRIVEIPITAVYTEYSMKKGTNVI-EGIKIALNLF 281 + VE K RIVE+PIT Y + K N + +G +I ++ Sbjct: 172 LTVETLAKGFRIVEVPIT--YRKRGGKTKLNPLRDGFRIGKTIY 213 >gi|11497940 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] >gi|7483293|pir||H69290 dolichol-P-glucose synthetase homolog - Archaeoglobus fulgidus >gi|2650309|gb|AAB90908.1| (AE001082) dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] Length = 371 Score = 105 bits (259), Expect = 7e-22 Identities = 68/212 (32%), Positives = 115/212 (54%), Gaps = 15/212 (7%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGLG 126 +V+P NEEK I +++ L V +E IIVVDD S D T EIA+ G V+ ++ +G G Sbjct: 4 VVLPTKNEEKAIEEIVKKCLVVGVKE-IIVVDD-STDSTPEIAEKLGCRVIKNV--KGYG 59 Query: 127 GALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNL--NQ 184 A G+++A +I+V DADG + + ++++P+ + D+ IGSRFKG + Sbjct: 60 NAYLEGLKHA---SGDIIVLMDADGTYDPAEIPKLVEPILRDEADVVIGSRFKGKIMPGA 116 Query: 185 MPLV-KRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVEA 243 MP K +GN L +T SD SG RA ++ S++ + C G ++E +++ Sbjct: 117 MPWHHKYLGNPLLTKLTNFLFGTGFSDVHSGFRAIKKSSLSQLDLKCPGMEFATEFVLKT 176 Query: 244 SRKKCRIVEIPITAVYTEYSMKKGTNVIEGIK 275 + R++E+P+T Y +KG + + + Sbjct: 177 TMSGLRLLEVPVT-----YYPRKGDSKLRSFR 203 >emb|CAC11300.1| (AL445063) conserved hypothetical protein [Thermoplasma acidophilum] Length = 225 Score = 98.3 bits (241), Expect = 9e-20 Identities = 75/195 (38%), Positives = 100/195 (50%), Gaps = 10/195 (5%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINR 123 K V+P NEE TIG V+D + FP IIVVD S DRTREIA+SKG V+ R Sbjct: 7 KVSFVIPTINEEGTIGSVIDGIRSEFPNSEIIVVDTNSTDRTREIARSKGARVIEE-PRR 65 Query: 124 GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSR--FKGN 181 G G A TGI A EI+V D DG + + +I+ + + D R F+ + Sbjct: 66 GYGRAYQTGIPAA---SGEIIVCMDGDGTYPTDVVKPLIELLIADRVDFISCDRITFRTS 122 Query: 182 LNQMPLVKRVGNIALNL-ITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEII 240 N L VGN+ LNL I +F R + D+QSG+ F ++K +G + S I Sbjct: 123 KNYTTL-HYVGNMVLNLTIRILFKVRMV-DSQSGMWVFRSEIYRKMKNLGNGMSFSQNIK 180 Query: 241 VEASRKKCRIVEIPI 255 +EA R +EIPI Sbjct: 181 IEAVRHGV-FMEIPI 194 >pir||B71154 hypothetical protein PH0433 - Pyrococcus horikoshii >gi|3256836|dbj|BAA29519.1| (AP000002) 304aa long hypothetical protein [Pyrococcus horikoshii] Length = 304 Score = 97.1 bits (238), Expect = 2e-19 Identities = 69/212 (32%), Positives = 108/212 (50%), Gaps = 15/212 (7%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGLG 126 I++P NEE+ IG V++ ++ NI+V+D S DRTREIAK KG VV +G G Sbjct: 12 ILIPTKNEEEGIGWVIEEFKKL-GYNNILVIDGHSTDRTREIAKEKGAKVVLQT-GKGKG 69 Query: 127 GALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLNQMP 186 A+ + +E+VV D DG + +D ++++P+ G + IG+R + + Sbjct: 70 QAVAEAFKLI---DSEVVVLIDGDGTYDPKDVEKMLEPIRRGIAEHVIGNRLENF--EDG 124 Query: 187 LVKRVGNIALNLITAIFAFRY---ISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVEA 243 R+ I + A+F F Y + D SG RAF++ V++ G+ V +E+ VE Sbjct: 125 AFTRLNLIGNKIFNALFRFLYGVPVYDMLSGYRAFTKELYKSVELKKHGFEVETELTVET 184 Query: 244 SRKKCRIVEIPITAVYTEYSMKKGTNVIEGIK 275 K RI E+PI Y +KG + IK Sbjct: 185 VAKGFRIAEVPI-----NYYKRKGKANLHPIK 211 >emb|CAC15463.1| (AJ294477) putative polyprenol phosphate mannosyl transferase 1 (Ppm1) [Mycobacterium smegmatis] Length = 265 Score = 94.4 bits (231), Expect = 1e-18 Identities = 65/224 (29%), Positives = 106/224 (47%), Gaps = 14/224 (6%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKG------VHVV 117 +T +++P YNE + + ++ + P+ +I+VVDDGS D T +A VHV+ Sbjct: 23 RTLVIIPTYNERENLPLIVGRVHHACPQVHILVVDDGSPDGTGALADELALADPDRVHVM 82 Query: 118 SHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSR 177 GLG A G + + +G ++V DADG H E+ R++ V G DLAIGSR Sbjct: 83 HRTSKAGLGAAYLAGFDWGLRRGYSVLVEMDADGSHAPEELSRLLDAVDAG-ADLAIGSR 141 Query: 178 F--KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITC---DG 232 + G + P + V + N + I D +G RA+ R ++ ++ G Sbjct: 142 YVPGGTVRNWPWRRLVLSKTANTYSRFLLGVGIHDITAGYRAYRREVLEKIDLSAVDSKG 201 Query: 233 YAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGI 274 Y ++ A +VE+PIT E + K G+N+ E + Sbjct: 202 YCFQIDLTWRAINNGFSVVEVPITFTERELGVSKMSGSNIREAM 245 >dbj|BAA19644.1| (AB002668) unnamed protein product [Actinobacillus actinomycetemcomitans] Length = 234 Score = 94.0 bits (230), Expect = 2e-18 Identities = 59/201 (29%), Positives = 110/201 (54%), Gaps = 15/201 (7%) Query: 63 MKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIIN 122 MK +++P YNE ++I +LD L + +P + IV++D +D T +I ++ G +V+ IN Sbjct: 1 MKILLIIPCYNESESIISLLDEL-KDYPEYDYIVINDCFKDNTSKIVRNYGANVIDLPIN 59 Query: 123 RGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF---K 179 GL G + TG+ YA +I + D DGQH+ + +++ + +G D+AI SRF K Sbjct: 60 LGLSGGVQTGMMYATKNDYDICIQIDGDGQHMPSEIYKLVDKIKDG-VDIAISSRFLESK 118 Query: 180 GNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSS-- 237 + +Q ++ +G + +F+ ++D SG+RAF++N ++ YA + Sbjct: 119 DSYSQ-TFLRALGAKHIQFCIKLFSGLTLTDPTSGMRAFTKNVFQQM-----AYATNERP 172 Query: 238 --EIIVEASRKKCRIVEIPIT 256 + ++ +R RI E+ +T Sbjct: 173 EPDTMLYFARLGYRIEEVQVT 193 >pir||E69142 mannosyltransferase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621387|gb|AAB84837.1| (AE000818) mannosyltransferase [Methanobacterium thermoautotrophicum] Length = 221 Score = 93.6 bits (229), Expect = 2e-18 Identities = 70/225 (31%), Positives = 116/225 (51%), Gaps = 13/225 (5%) Query: 68 VMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGLGG 127 ++PAYNEEK+IG ++D + + P IIVVD+ S DRT EIA S+GV V+ +G Sbjct: 4 LIPAYNEEKSIGPLIDRIKMLCPDSEIIVVDNNSSDRTSEIATSRGVRVIFE-GKQGKAN 62 Query: 128 ALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLNQ--M 185 A+ R E V DAD ++ +D+ +++ + D+ +GSR G + Sbjct: 63 AMVAAFRNT---RTEYAVMMDADLTYLPDDSRVLVEVLKAEGADVVLGSRLNGEKEDGAI 119 Query: 186 PLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV---KITCDGYAVSSEIIVE 242 + VGN L+ TA + +SD +G AF+R + + G+ + +E+ + Sbjct: 120 SRINTVGNHILS-FTASILYSPVSDVCTGHWAFNRRAIRHILEEGLNYSGFELEAEMFSK 178 Query: 243 ASRKKCRIVEIPITAVYTEYSMK-KGTNVIEGIKIALNLFVDLFR 286 +R +IVE+PIT Y + S + K ++ +G KI L ++ R Sbjct: 179 LARAGLKIVEVPIT--YRKRSDEPKLSSFTDGFKIFRTLVLERLR 221 >pir||F75058 dolichol-p-glucose synthetase PAB1411 - Pyrococcus abyssi (strain Orsay) >gi|5458876|emb|CAB50363.1| (AJ248287) DOLICHOL-P-GLUCOSE SYNTHETASE [Pyrococcus abyssi] Length = 378 Score = 93.2 bits (228), Expect = 3e-18 Identities = 62/196 (31%), Positives = 102/196 (51%), Gaps = 10/196 (5%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENI---IVVDDGSRDRTREIAKSKGVHVVSHIINR 123 +++P NEEK + V+ + + + I+V D S D+T EIA++ G V+ + Sbjct: 12 VILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQK-GK 70 Query: 124 GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLN 183 G G A G + A KG IV+ D DG + ++ ++++ + + D IGSR KG + Sbjct: 71 GYGDAYLEGFKVA--KGKYIVM-MDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIE 127 Query: 184 Q--MPLVKR-VGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEII 240 MP + R +GN L I +SD SG RA R+ ++ + C G +SE+I Sbjct: 128 PGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMI 187 Query: 241 VEASRKKCRIVEIPIT 256 +EA++ +I E+PIT Sbjct: 188 IEAAKAGLKIAEVPIT 203 >pir||B75100 glycosyltransferase PAB1587 - Pyrococcus abyssi (strain Orsay) >gi|5458615|emb|CAB50103.1| (AJ248286) glycosyltransferase [Pyrococcus abyssi] Length = 233 Score = 92.8 bits (227), Expect = 4e-18 Identities = 62/201 (30%), Positives = 109/201 (53%), Gaps = 11/201 (5%) Query: 62 LMKTYIVMPAYNEEKTIGDVLDSL-LRVFPREN----IIVVDDGSRDRTREIAKSKGVHV 116 + + +++PAYNEE+TIG V+D + ++ +E ++V + S DRT EIA++KG + Sbjct: 1 MKRVVVLLPAYNEEETIGKVIDEIPVKKLEKEGYKVTVVVANGPSTDRTEEIARNKGA-I 59 Query: 117 VSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGS 176 V +I G + + + + +V DAD + + ++K + E D+ IGS Sbjct: 60 VYNIAKGGKARDVKHALSMIDFP-YDYLVMLDADYTYPPQYIYDIVKALEE--YDVVIGS 116 Query: 177 RFKGNLNQ--MPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYA 234 R KG + MP V ++GN L+LI I + ISD +G+ F + ++I +G+ Sbjct: 117 RLKGKIEDGAMPKVNKLGNWGLSLIATILYGKKISDVCTGMWGFRKYVLDSIEIDANGFD 176 Query: 235 VSSEIIVEASRKKCRIVEIPI 255 + + + VEA +K +I E+PI Sbjct: 177 LEANLYVEAVKKGFKIGEVPI 197 >pir||C69052 conserved hypothetical protein MTH1392 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622503|gb|AAB85869.1| (AE000902) dolichyl-phosphate mannoosyltransferase related protein [Methanobacterium thermoautotrophicum] Length = 564 Score = 90.9 bits (222), Expect = 2e-17 Identities = 64/206 (31%), Positives = 106/206 (51%), Gaps = 11/206 (5%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGLG 126 +V+PA NEEKT+G V+++ + + +IVVDDGS D T A+ G V+ H NRG G Sbjct: 27 VVIPALNEEKTVGSVIEAARKSDMVDEVIVVDDGSTDNTAGAAEDAGATVIRHTSNRGKG 86 Query: 127 GALGTGIRYAVYKGAEIVVTFDADGQHIVEDAL-RVIKPVAEGKTDLAIGSRFKGNLNQM 185 AL TG +++ +IVV DAD +++ + + R+IKP+ G+ DL +RF+ ++ Sbjct: 87 AALKTGFKHS---RGDIVVFVDADLENMTTEKIERMIKPIITGRADLT-KTRFRRKAGRV 142 Query: 186 PLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVEASR 245 + A L+ F SG A R+ ++K D Y V I+++A Sbjct: 143 TEL-----TAKPLLKFFFPEIKFEQPLSGQFAAKRSALEKMKFEED-YGVDVGIVLDADV 196 Query: 246 KKCRIVEIPITAVYTEYSMKKGTNVI 271 + E+ I ++ + + K NV+ Sbjct: 197 LGLTVREVDIGNIHHDMASLKDLNVV 222 >pir||E82657 dolichyl-phosphate mannose synthase related protein XF1638 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106693|gb|AAF84447.1|AE003990_10 (AE003990) dolichyl-phosphate mannose synthase related protein [Xylella fastidiosa] Length = 274 Score = 87.0 bits (212), Expect = 2e-16 Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 4/197 (2%) Query: 65 TYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRG 124 T I++PA NE +I V+ L P ++IVVDDGS D T + ++ H RG Sbjct: 11 TAIIIPALNEALSIRKVITDALAYCP--HVIVVDDGSDDGTANCISDLPIILIRHPQRRG 68 Query: 125 LGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLNQ 184 G AL +G A G + V+T D DGQH D R++ + IG+R + ++ Sbjct: 69 KGAALRSGFAAATQLGVQGVITMDGDGQHSAADFPRLLAAANYHPGCVIIGARLR-KRSE 127 Query: 185 MPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVEAS 244 P ++R+GN + + I DTQSG R + + + ++ + + +++++ A+ Sbjct: 128 QPWIRRIGNHFGDWGISWGCGCRIVDTQSGQRFYPASVFTLPDVSGEDFVFEAQLLISAA 187 Query: 245 RKK-CRIVEIPITAVYT 260 R+ R++ +PI A Y+ Sbjct: 188 RQAGARMIAVPIEARYS 204 >gb|AAK43334.1| Dolichol-phosphate mannosyltransferase [Sulfolobus solfataricus] Length = 255 Score = 86.2 bits (210), Expect = 4e-16 Identities = 70/229 (30%), Positives = 109/229 (47%), Gaps = 15/229 (6%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFP-RENIIVVDDGSRDRTREIAKSKGVHVVSHIIN--- 122 IV+P YNE I +++ + R+ P I++VDD S D T I + +H ++ +I Sbjct: 28 IVIPTYNERDNIVKLVEEINRIVPYNSRILIVDDNSPDGTALILQELNIHNLTVLIRHNE 87 Query: 123 RGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF--KG 180 RGLG AL GI A+ ++ +VT DAD H + ++K DL IGSR+ G Sbjct: 88 RGLGSALRYGISKAIELESDFIVTMDADFSHNPKYLPEMMKIALNENCDLVIGSRYVIGG 147 Query: 181 NLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCD---GYAVSS 237 + L +R+ + N + + + I D S R +SR A+ + + CD GY Sbjct: 148 GIENWSLSRRIISKGANYLFKLVSHSPIMDNTSNYRIYSRR-AALLALECDTTNGYEFQI 206 Query: 238 EIIVEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFVDLFR 286 I + R +I E PI V K G + + +K LN F+ + R Sbjct: 207 CSIFKIIRNNLKIKEYPIIFV----DRKTGKSKL-NLKEILNWFLYIIR 250 >gb|AAC35924.1| (AF071085) putative glycosyl transferase [Enterococcus faecalis] Length = 241 Score = 85.4 bits (208), Expect = 7e-16 Identities = 60/204 (29%), Positives = 99/204 (48%), Gaps = 12/204 (5%) Query: 63 MKTYIVMPAYNEEKTIGDVLDSLLRVFPRE--------NIIVVDDGSRDRTREIAKSKGV 114 MK +++PAYNEE+ I + S+ F +E + +V++DGS D T++I + + Sbjct: 1 MKVLLIIPAYNEEENILRTIASI-ETFKQEVTHFQHELDYVVINDGSTDGTKQILEVNQI 59 Query: 115 HVVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAI 174 + + ++N G+GGA+ TG +YA+ ++ FD DG H + +++P+AEG + Sbjct: 60 NAIHLVLNLGIGGAVQTGYKYALENEYDVAXQFDGDGXHDIXSLPILLEPLAEGXCXFSX 119 Query: 175 GSRF-KGNLN--QMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCD 231 GSRF GN Q ++R G L+ I G RA +R + Sbjct: 120 GSRFIPGNXASFQSXKMRRXGIRLLSFCXXXAXGXTIYXVTXGXRAGNRKVIAFFAKRYP 179 Query: 232 GYAVSSEIIVEASRKKCRIVEIPI 255 E IV +K+ IVE P+ Sbjct: 180 TNYPEPESIVHLIKKRFVIVERPV 203 >gb|AAD30975.1|AF121895_1 (AF121895) dolichol-phosphate-mannose synthase [Cricetulus griseus] Length = 266 Score = 82.3 bits (200), Expect = 6e-15 Identities = 68/235 (28%), Positives = 110/235 (45%), Gaps = 20/235 (8%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRENI----IVVDDGSRDRTREIAKS-KGVHVVS 118 K +++P YNE + + ++ L++ F +I I++DDGS D TRE+A+ + ++ Sbjct: 32 KYSVLLPTYNERENLPLIVWLLVKSFSESSINYEIIIIDDGSPDGTREVAEQLEKIYGPD 91 Query: 119 HIINR------GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDL 172 I+ R GLG A GI++A V+ DAD H + I+ EG D+ Sbjct: 92 RILLRPREKKLGLGTAYIHGIKHAT---GNYVIIMDADLSHHPKFIPEFIRKQKEGNFDI 148 Query: 173 AIGSRFKGN--LNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV--KI 228 G+R+KGN + L +++ + N IT I SD R + + ++ K Sbjct: 149 VSGTRYKGNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKC 208 Query: 229 TCDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGIKIALNLF 281 GY E+IV A + I E+PI+ V Y K G ++ +K L LF Sbjct: 209 VSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLF 263 >gb|AAC98797.1| (AF007875) dolichol monophosphate mannose synthase [Homo sapiens] Length = 253 Score = 81.9 bits (199), Expect = 8e-15 Identities = 68/245 (27%), Positives = 114/245 (45%), Gaps = 20/245 (8%) Query: 54 ELKSLVGRLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENI----IVVDDGSRDRTREIA 109 EL+ R K +++P YNE + + ++ L++ F I I++DDGS D TR++A Sbjct: 9 ELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVA 68 Query: 110 KS-KGVHVVSHIINR------GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVI 162 + + ++ I+ R GLG A G+++A ++ DAD H + I Sbjct: 69 EQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHAT---GNYIIIMDADLSHHPKFIPEFI 125 Query: 163 KPVAEGKTDLAIGSRFKGN--LNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSR 220 + EG D+A G+R+KGN + L +++ + N +T I SD R + + Sbjct: 126 RKKKEGNFDIASGTRYKGNGGIYGWDLKRKIISRGANFLTQILLTPGASDLTGSFRLYPK 185 Query: 221 NCASRV--KITCDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGIKI 276 ++ K GY E+IV A + I E+PI+ V Y K G ++ +K Sbjct: 186 EVLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSFLKG 245 Query: 277 ALNLF 281 L LF Sbjct: 246 LLTLF 250 >gi|6753670 dolichol-phosphate (beta-D) mannosyltransferase 1 [Mus musculus] >gi|3073773|dbj|BAA25759.1| (AB004789) dolichol-phosphate-mannose synthase [Mus musculus] Length = 260 Score = 81.9 bits (199), Expect = 8e-15 Identities = 68/235 (28%), Positives = 108/235 (45%), Gaps = 20/235 (8%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRE----NIIVVDDGSRDRTREIAKSKG-VHVVS 118 K +++P YNE + + ++ L++ F II++DDGS D TRE+A+ ++ Sbjct: 26 KYSVLLPTYNERENLPLIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIYGPD 85 Query: 119 HIINR------GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDL 172 I+ R GLG A GI++A V+ DAD H + I+ EG D+ Sbjct: 86 RILLRPREKKLGLGTAYIHGIKHAT---GNYVIIMDADLSHHPKFIPEFIRKQKEGNFDI 142 Query: 173 AIGSRFKGN--LNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV--KI 228 G+R+KGN + L +++ + N IT I SD R + + ++ K Sbjct: 143 VSGTRYKGNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKC 202 Query: 229 TCDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGIKIALNLF 281 GY E+IV A + I E+PI+ V Y K G ++ +K L LF Sbjct: 203 VSKGYVFQMEMIVRARQMNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLF 257 >pir||G75191 dolichol-phosphate mannosyltransferase PAB2307 - Pyrococcus abyssi (strain Orsay) >gi|5457491|emb|CAB48982.1| (AJ248283) DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE [Pyrococcus abyssi] Length = 362 Score = 81.9 bits (199), Expect = 8e-15 Identities = 64/206 (31%), Positives = 104/206 (50%), Gaps = 18/206 (8%) Query: 62 LMKTYIVMPAYNEEKTIGDV---LDSLLRVFPRENIIVVDDGSRDRT----REIAKSKGV 114 +MK +++P YNE + + ++ +D L+ + E IIVVDD S D T +E++ V Sbjct: 11 IMKVSVIVPTYNERENLEELFSRIDKALKDYDYE-IIVVDDDSPDETWKKAQELSSVYPV 69 Query: 115 HVVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAI 174 V+ I +GL A+ G + A ++ V DAD QH E ++K + EG DLAI Sbjct: 70 KVIRRINEKGLSSAVIRGFKEA---SGDVFVVMDADLQHPPEVIPELLKRIKEG-ADLAI 125 Query: 175 GSRFK--GNLNQMPLVKRVGNIALNLIT--AIFAFRYISDTQSGLRAFSRNCASRVKITC 230 SR+ G + PL +++ + +I A+ R I D SG A RN V + Sbjct: 126 ASRYVKGGRVENWPLYRKLISKGAIMIARVALPKIRSIKDPVSGFFALKRNVVDNVNLNP 185 Query: 231 DGYAVSSEIIVEASRKKCRIVEIPIT 256 G+ + EI+++ + R+ E+P T Sbjct: 186 IGFKILLEILIKG--RYSRVEEVPFT 209 >emb|CAB11300.1| (Z98604) hypothetical protein MLCB2052.02 [Mycobacterium leprae] Length = 277 Score = 81.1 bits (197), Expect = 1e-14 Identities = 58/221 (26%), Positives = 98/221 (44%), Gaps = 14/221 (6%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKG------VHVVSHI 120 +++P +NE + + L +P ++++VDDGS D T E+A HV+ Sbjct: 21 VIIPTFNELENLPVTHGRLKDAYPEIHVLIVDDGSPDGTGELADELAQVDPGCTHVMHRT 80 Query: 121 INRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRF-- 178 GLG A G + + + ++V DADG H E R++ V G DLAIGSR+ Sbjct: 81 TKDGLGTAYLAGFAWGMSRDYSVLVEMDADGSHAPEQLHRLLGAVDAG-ADLAIGSRYVN 139 Query: 179 KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV---KITCDGYAV 235 G + P + + N + + + D +G RA+ R + + GY Sbjct: 140 GGTVRNWPWQRLALSKTANKYSRLALGIDVHDITAGYRAYRREVLEAIDLDSVASKGYCF 199 Query: 236 SSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGI 274 ++ I+E+PIT E+ + K G+N+ E + Sbjct: 200 QIDLTWRTVNNGFVIIEVPITFTEREFGLSKMSGSNIREAL 240 >gi|4503363 dolichyl-phosphate mannosyltransferase polypeptide 1; dolichol monophosphate mannose synthase [Homo sapiens] >gi|11420524|ref|XP_009467.1| dolichyl-phosphate mannosyltransferase polypeptide 1 [Homo sapiens] >gi|3062806|dbj|BAA25646.1| (D86198) dolichol-phosphate-mannose synthase [Homo sapiens] >gi|5817251|emb|CAB53749.1| (AL034553) dJ914P20.1 (dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit) [Homo sapiens] Length = 260 Score = 80.0 bits (194), Expect = 3e-14 Identities = 69/254 (27%), Positives = 116/254 (45%), Gaps = 20/254 (7%) Query: 45 TRYEAESFDELKSLVGRLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENI----IVVDDG 100 +R S EL+ R K +++P YNE + + ++ L++ F I I++DDG Sbjct: 7 SRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDG 66 Query: 101 SRDRTREIAKS-KGVHVVSHIINR------GLGGALGTGIRYAVYKGAEIVVTFDADGQH 153 S D TR++A+ + ++ I+ R GLG A G+++A ++ DAD H Sbjct: 67 SPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHAT---GNYIIIMDADLSH 123 Query: 154 IVEDALRVIKPVAEGKTDLAIGSRFKGN--LNQMPLVKRVGNIALNLITAIFAFRYISDT 211 + I+ EG D+ G+R+KGN + L +++ + N +T I SD Sbjct: 124 HPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFLTQILLRPGASDL 183 Query: 212 QSGLRAFSRNCASRV--KITCDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--G 267 R + + ++ K GY E+IV A + I E+PI+ V Y K G Sbjct: 184 TGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGG 243 Query: 268 TNVIEGIKIALNLF 281 ++ +K L LF Sbjct: 244 NEIVSFLKGLLTLF 257 >gb|AAF80640.1|AC069251_33 (AC069251) F2D10.6 [Arabidopsis thaliana] Length = 246 Score = 80.0 bits (194), Expect = 3e-14 Identities = 65/235 (27%), Positives = 110/235 (46%), Gaps = 12/235 (5%) Query: 53 DELKSLVGRLMKTYIVMPAYNEEKTIGDVLDSLLRVFPREN--IIVVDDGSRDRTREIAK 110 DE+++ + K I++P YNE I ++ + + + IIVVDDGS D T+EI K Sbjct: 3 DEMETKGEKKYKYSIIIPTYNERLNIAIIVYLIFKHLRDVDFEIIVVDDGSPDGTQEIVK 62 Query: 111 S-KGVHVVSHIINRGLGGALGTGIRYA---VYKGAEIVVTFDADGQHIVEDALRVIKPVA 166 + ++ I+ R LG G Y + + VV DAD H + IK Sbjct: 63 QLQQLYGEDRILLRARAKKLGLGTAYIHGLKHATGDFVVIMDADLSHHPKYLPSFIKKQL 122 Query: 167 EGKTDLAIGSRFK--GNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCAS 224 E + G+R+ G ++ L++++ + N++ + +SD R + ++ Sbjct: 123 ETNASIVTGTRYVKGGGVHGWNLMRKLTSRGANVLAQTLLWPGVSDLTGSFRLYKKSALE 182 Query: 225 RVKITC--DGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGIK 275 V +C GY E+IV A+RK I E+PIT V + K G+ ++E +K Sbjct: 183 DVISSCVSKGYVFQMEMIVRATRKGYHIEEVPITFVDRVFGTSKLGGSEIVEYLK 237 >pir||B70945 hypothetical protein Rv2051c - Mycobacterium tuberculosis (strain H37RV) >gi|2896788|emb|CAA17265.1| (AL021899) hypothetical protein Rv2051c [Mycobacterium tuberculosis] Length = 874 Score = 80.0 bits (194), Expect = 3e-14 Identities = 60/228 (26%), Positives = 101/228 (43%), Gaps = 15/228 (6%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKG------VHVV 117 + +++P +NE + + + L + P +++VVDD S D T ++A HV+ Sbjct: 611 RVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPDGTGQLADELAQADPGRTHVM 670 Query: 118 SHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSR 177 GLG A G + + + ++V DADG H E R++ V G DLAIGSR Sbjct: 671 HRTAKNGLGAAYLAGFAWGLSREYSVLVEMDADGSHAPEQLQRLLDAVDAG-ADLAIGSR 729 Query: 178 F--KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVK---ITCDG 232 + G + P + V + N + + I D +G RA+ R + + G Sbjct: 730 YVAGGTVRNWPWRRLVLSKTANTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKG 789 Query: 233 YAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEG-IKIA 277 Y ++ + E+PIT E + K G+N+ E +K+A Sbjct: 790 YCFQIDLTWRTVSNGFVVTEVPITFTERELGVSKMSGSNIREALVKVA 837 >gb|AAG32629.1|AF102883_1 (AF102883) mannose phospho-dolichol synthase [Hypocrea jecorina] Length = 243 Score = 79.6 bits (193), Expect = 4e-14 Identities = 60/232 (25%), Positives = 102/232 (43%), Gaps = 13/232 (5%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRENI----IVVDDGSRDRTREIAKSKGVHVVSH 119 K +++P YNE K + V L R F + I+VDDGS D T+++A H Sbjct: 10 KYSVILPTYNERKNLPIVAWLLNRTFTEHQLDWELIIVDDGSPDGTQDVANQLVKAYAPH 69 Query: 120 IINRGLGGALGTGIRYA---VYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGS 176 ++ + G LG G Y + V+ DAD H + ++I +G D+ G+ Sbjct: 70 VVLKTRSGKLGLGTAYVHGLQFVTGNFVIIMDADFSHHPKFIPQMIAVQKKGNYDIVTGT 129 Query: 177 RFKGN--LNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCD--G 232 R+ GN + L ++ + NL +SD R + ++ +V + + G Sbjct: 130 RYAGNGGVFGWDLKRKFVSRGANLFADTVLRPGVSDLTGSFRLYKKSVLEKVISSTESKG 189 Query: 233 YAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGIKIALNLFV 282 Y E++V A C + E+PI+ V Y K G ++E K +L++ Sbjct: 190 YTFQMEMMVRAKAMGCTVAEVPISFVDRVYGESKLGGDEIVEYAKGVFSLWL 241 >gb|AAF53817.1| (AE003663) CG10166 gene product [Drosophila melanogaster] Length = 241 Score = 78.8 bits (191), Expect = 7e-14 Identities = 63/232 (27%), Positives = 105/232 (45%), Gaps = 14/232 (6%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPREN----IIVVDDGSRDRTREIAKS-KGVHVVS 118 K I+MP YNE+ + ++ +++ +IV+DDGS D T ++AK + ++ Sbjct: 7 KYSILMPTYNEKDNLPIIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYGED 66 Query: 119 HIINRGLGGALGTGIRYA---VYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIG 175 I+ R G LG G Y + + +V DAD H + IK EG D+ G Sbjct: 67 KIVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIVSG 126 Query: 176 SRFKGN--LNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITC--D 231 +R+ GN + +++ + N ++ + SD R + ++ + +C Sbjct: 127 TRYAGNGGVFGWDFKRKLISRGANFLSQVLLRPNASDLTGSFRLYKKDVLEKCIASCVSK 186 Query: 232 GYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK--GTNVIEGIKIALNLF 281 GY E++V A + I E+PIT V Y K GT +I+ K L LF Sbjct: 187 GYVFQMEMLVRARQHGYTIAEVPITFVDRIYGTSKLGGTEIIQFAKNLLYLF 238 >sp|Q57964|Y544_METJA HYPOTHETICAL PROTEIN MJ0544 >gi|2127875|pir||H64367 dolichyl-phosphate mannose synthase - Methanococcus jannaschii >gi|1592295|gb|AAB98538.1| (U67504) dolichyl-phosphate mannose synthase [Methanococcus jannaschii] Length = 229 Score = 78.4 bits (190), Expect = 9e-14 Identities = 58/205 (28%), Positives = 102/205 (49%), Gaps = 19/205 (9%) Query: 68 VMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIA-----KSK-GVHVVSHII 121 ++PA+NEEK I VL L ++ R + +VVDDGS+D T +I K+K V+++ + Sbjct: 4 IIPAFNEEKNILKVLKDLEKL--RVDAVVVDDGSKDNTSKIVEEFAKKAKINVYLIRNEK 61 Query: 122 NRGLGGALGTGIRYAV-YKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKG 180 N G A+ G ++A+ + ++ D D QH D +++K + + D G R Sbjct: 62 NEGKAKAIEKGTKFALSLNKYKYIIYIDGDYQHKPMDIPKLLKKLEDTNADAVFGIR--- 118 Query: 181 NLNQMPLVKRVGNIALNLITAIFA------FRYISDTQSGLRAFSRNCASRVKITCDGYA 234 +PL +++ N +++T++ F + D Q G R +K DGYA Sbjct: 119 KYKHIPLHRQISNFFASILTSLAVLIYSKRFYFFRDVQCGFRIIKAEFLKDMKFG-DGYA 177 Query: 235 VSSEIIVEASRKKCRIVEIPITAVY 259 V I ++ ++K +IVE ++ Y Sbjct: 178 VEHFIALQLAKKGAKIVEEYVSVEY 202 >emb|CAB61668.1| (AL133213) putative glycosyl transferase. [Streptomyces coelicolor A3(2)] Length = 302 Score = 76.1 bits (184), Expect = 4e-13 Identities = 57/217 (26%), Positives = 96/217 (43%), Gaps = 12/217 (5%) Query: 60 GRLMKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKG-----V 114 G L +++P YNE + I ++ + P +++V DD S D T ++A V Sbjct: 18 GPLGTALVIIPTYNEAENIKAIVTRVREAVPEAHVLVADDNSPDGTGKLADELAAADDHV 77 Query: 115 HVVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAI 174 V+ GLG A G R+ + G +++ DADG H E+ R++ A DL + Sbjct: 78 QVMHRKGKEGLGAAYLAGFRWGLEHGYGVLIEMDADGSHQPEELPRLL--TALKGADLVL 135 Query: 175 GSRF--KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV---KIT 229 GSR+ G + P + + + ++ + I + D G RAF R + ++ Sbjct: 136 GSRWVPGGRVVNWPKSREIISRGGSMYSRIALDLPLRDITGGYRAFRRETLEGLGLEEVA 195 Query: 230 CDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK 266 GY ++ A + +VE+PIT V E K Sbjct: 196 SQGYCFQVDLARRAIKAGYHVVEVPITFVERELGDSK 232 >pir||H71223 probable dolichol-phosphate mannosyltransferase - Pyrococcus horikoshii >gi|3256436|dbj|BAA29119.1| (AP000001) 353aa long hypothetical dolichol-phosphate mannosyltransferase [Pyrococcus horikoshii] Length = 353 Score = 75.7 bits (183), Expect = 6e-13 Identities = 63/211 (29%), Positives = 101/211 (47%), Gaps = 30/211 (14%) Query: 63 MKTYIVMPAYNEEKTIGDV---LDSLLRVFPRENIIVVDDGSRDRT----REIAKSKGVH 115 MK I++P YNE + ++ + S L+ + E II+VDD S D+T E++K V Sbjct: 1 MKVSIIVPTYNERDNLEELFSRISSALKGYDYE-IIIVDDDSPDKTWEKAMELSKLYPVK 59 Query: 116 VVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIG 175 V+ + +GL A+ G A ++ V DAD QH E +++ + +G D+AI Sbjct: 60 VIRRVNEKGLSSAVIRGFSEA---SGDVFVVMDADLQHPPEVIPSLLREIEKGN-DIAIA 115 Query: 176 SRFK--GNLNQMPLVKR--------VGNIALNLITAIFAFRYISDTQSGLRAFSRNCASR 225 SR+ G + P +R +G +AL I I D SG A R+ Sbjct: 116 SRYVKGGKVENWPFYRRLISRGAIIIGRLALPKIAGI------KDPVSGFFALKRSVVEG 169 Query: 226 VKITCDGYAVSSEIIVEASRKKCRIVEIPIT 256 VK+ G+ + EI+++ K R+ E+P T Sbjct: 170 VKLNPIGFKILMEILIKG--KYSRVTEVPFT 198 >pir||B75440 rfbJ protein/conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6458811|gb|AAF10652.1|AE001958_6 (AE001958) rfbJ protein/conserved hypothetical protein [Deinococcus radiodurans] Length = 219 Score = 75.3 bits (182), Expect = 8e-13 Identities = 42/110 (38%), Positives = 66/110 (59%), Gaps = 6/110 (5%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGLG 126 +V+PA+NEE+T+GDV+ + L + P ++V DGS D T ++A++ G VV + N G G Sbjct: 14 VVIPAFNEEETVGDVVRAALTLTPE--VVVASDGSADATAQVARTAGARVVELLENAGKG 71 Query: 127 GALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRV-IKPVAEGKTDLAIG 175 AL ++ AE VV D D Q + + L V ++PV +G+ D+ IG Sbjct: 72 PALAAALQAT---DAEYVVMLDGDLQGLTREHLDVLLRPVLDGELDMTIG 118 >gb|AAG19457.1| (AE005038) glycosyl transferase-like; Gtl [Halobacterium sp. NRC-1] Length = 305 Score = 74.5 bits (180), Expect = 1e-12 Identities = 61/218 (27%), Positives = 96/218 (43%), Gaps = 11/218 (5%) Query: 68 VMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGLGG 127 ++P NE TI DV+D L V +++VVD S D T +A G VV G G Sbjct: 11 LVPTRNEAATIADVIDGLFEVGVG-HVLVVDGNSADDTAAVAAEHGAEVVQQS-GDGKGQ 68 Query: 128 ALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKG-NLNQMP 186 A+ G+ A V+ D DG + A R++ P+ G+ + +G R M Sbjct: 69 AVREGVSLIE---AAYVLLLDGDGTNPPAQASRLLDPLVAGEAEHVVGDRTADMRPGAMS 125 Query: 187 LVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVEASRK 246 + ++GN +N D SG RAF+ R+ ++ +G+ + +E+ VE SR Sbjct: 126 TLNQIGNRLINRAFHRIHGEDYGDILSGYRAFTAESFDRMFLSAEGFGIETEMAVECSRH 185 Query: 247 KCRIVEIPITAVYTEYSMKKGTN---VIEGIKIALNLF 281 +P T Y TN + +G +I L L+ Sbjct: 186 NITTRVVPTT--YRARPDDSETNLHPISDGARIILTLY 221 >pir||T38633 dolichol monophosphate mannose synthase - fission yeast (Schizosaccharomyces pombe) >gi|2258414|gb|AAC98795.1| (AF007873) dolichol monophosphate mannose synthase [Schizosaccharomyces pombe] >gi|2388967|emb|CAB11700.1| (Z98979) dolichol-phosphate mannosyltransferase [Schizosaccharomyces pombe] Length = 236 Score = 71.4 bits (172), Expect = 1e-11 Identities = 55/217 (25%), Positives = 95/217 (43%), Gaps = 12/217 (5%) Query: 62 LMKTYIVMPAYNEEKTIGDVLDSLLRVFPREN----IIVVDDGSRDRTREIAKS-KGVHV 116 + K +++P YNE K + + + + F +E I+++DD S D T+E+AK + ++ Sbjct: 1 MSKYSVLLPTYNERKNLPIITYLIAKTFDQEKLDWEIVIIDDASPDGTQEVAKELQKIYG 60 Query: 117 VSHIINRGLGGALGTGIRYA---VYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLA 173 I+ + G LG G Y + + V+ DAD H + IK E D+ Sbjct: 61 EDKILLKPRSGKLGLGTAYIHGLKFATGDFVIIMDADFSHHPKYLPEFIKLQKEHNYDIV 120 Query: 174 IGSRFK--GNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRV--KIT 229 +G+R+ G + L ++ + NL+ + +SD R + + + ++T Sbjct: 121 LGTRYAKDGGVYGWNLKRKFISRGANLLASTVLGTGVSDVTGSFRLYKKPVLETLMSEVT 180 Query: 230 CDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKK 266 GY EII A I E+PI V Y K Sbjct: 181 SKGYVFQMEIIARAREHNYTIGEVPIAFVDRLYGESK 217 >gb|AAD01952.1| (AF033015) unknown [Listeria monocytogenes] Length = 315 Score = 71.4 bits (172), Expect = 1e-11 Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 19/227 (8%) Query: 64 KTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINR 123 K +++P YNEE TIG V+D + P +I V D+ S+D+T EIAK G +V + + Sbjct: 7 KVAVLLPCYNEELTIGKVIDDFKKELPNADIYVYDNNSKDKTFEIAKDHGA-IVRKEMRQ 65 Query: 124 GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNL- 182 G G + + A+ + D D + E +++ + + ++ IG R Sbjct: 66 GKGNVVRSMFADI---DADYYLMVDGDDTYPAEYCHEILEVLRNKEANMVIGDRLSNGTY 122 Query: 183 ---NQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEI 239 N+ ++ N I IF + D +G R F R + + G+ + +E+ Sbjct: 123 TEENKRNFHDFGNSLVRNTINRIFKSN-LRDIMTGYRGFDRYFVKTMPVLSPGFEIETEM 181 Query: 240 IVEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIALNLFVDLFR 286 + A + + EI I +Y + EG + LN F D F+ Sbjct: 182 SIHALENRFLVKEIEI-----DYRDRP-----EGSESKLNTFSDGFK 218 >pir||T40534 dolichyl-phosphate beta-gluco syltransferase - fission yeast (Schizosaccharomyces pombe) >gi|3116140|emb|CAA18889.1| (AL023288) dolichyl-phosphate beta-glucosyltransferase [Schizosaccharomyces pombe] Length = 322 Score = 71.0 bits (171), Expect = 1e-11 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 34/244 (13%) Query: 67 IVMPAYNEEKTIGDVL----DSLLRVF--------PRENIIVVDDGSRDRT--------R 106 +++PAYNE K IG++L D L + + R I++VDD S+D T Sbjct: 66 VIVPAYNESKRIGNMLQETVDHLEKYYRSSSSAGQRRWEILIVDDESKDTTVNAVLEFSN 125 Query: 107 EIAKSKGVHVVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVA 166 ++ + V S NRG GGA+ G+ YA + + DADG D + K + Sbjct: 126 KLDLRDHLRVCSLKRNRGKGGAVTWGMLYA---RGQYAIFADADGASQFSDLELLFKNMP 182 Query: 167 EG-KTDLAIGSRFKGNLNQMPLVKR--VGNIALNL---ITAIFAFRYISDTQSGLRAFSR 220 G + + +GSR +N +VKR + N ++ + I R I DTQ G + FSR Sbjct: 183 PGPRGGVVVGSR-AHMVNTAAVVKRSFIRNFLMHCFHKLLQILGIREIGDTQCGFKLFSR 241 Query: 221 NCASRV--KITCDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGIKIAL 278 + ++ +G+ E++ A I+E+PIT + E K T + + I +A+ Sbjct: 242 EAYQSIFPRMHVEGWIFDIEVLTLARFFGLPIIEVPIT--WHEVGGSKMTLLKDSISMAI 299 Query: 279 NLFV 282 +L V Sbjct: 300 DLLV 303 >gb|AAG19351.1| (AE005030) galactosyltransferase homolog; Gst [Halobacterium sp. NRC-1] Length = 229 Score = 70.2 bits (169), Expect = 3e-11 Identities = 52/189 (27%), Positives = 84/189 (43%), Gaps = 6/189 (3%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIINRGLG 126 + M YNE I VL + +V DGS DRT EIA+ G V+ +G G Sbjct: 13 VAMGTYNEAAAIDTVLTDIADATDDRARVVCVDGSSDRTPEIAREHGATVIEQE-PQGYG 71 Query: 127 GALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLNQMP 186 A+ + A +V+T D D + +E + + EG D+ G R + MP Sbjct: 72 VAVAAALDAA---DTPVVITTDCDNTYPMERIPAFLARINEGY-DVVSGDRLYWGADTMP 127 Query: 187 LVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVEASRK 246 R+GN A IT++ + DT +G+RA+ + T +S+E+++ + Sbjct: 128 AFNRLGNAAFAAITSLLVGERVHDTTTGMRAYRAPVIDAIDWT-QNTGLSAELLIRPLCR 186 Query: 247 KCRIVEIPI 255 ++E PI Sbjct: 187 NYDVIEEPI 195 >gi|7019323 dolichyl phosphate glucosyltransferase; Alg5, S. cerevisiae, homolog of [Homo sapiens] >gi|11359864|pir||T51776 dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) [imported] - human >gi|5281121|gb|AAD41465.1|AF102850_1 (AF102850) dolichyl-phosphate beta-glucosyltransferase [Homo sapiens] >gi|6841520|gb|AAF29113.1|AF161498_1 (AF161498) HSPC149 [Homo sapiens] Length = 324 Score = 69.9 bits (168), Expect = 3e-11 Identities = 61/215 (28%), Positives = 103/215 (47%), Gaps = 29/215 (13%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPREN---------IIVVDDGSRDRTREIA-------K 110 +V+P+YNEEK + ++D L + +IVVDDGS+D+T ++A Sbjct: 69 VVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQKYG 128 Query: 111 SKGVHVVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAE--- 167 S V V++ + NRG GGA+ GI + +G +I++ DADG D ++ K + + Sbjct: 129 SDKVRVITLVKNRGKGGAIRMGIFSS--RGEKILMA-DADGATKFPDVEKLEKGLNDLQP 185 Query: 168 --GKTDLAIGSRF---KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNC 222 + +A GSR K ++ Q + + + + + I DTQ G + F+R Sbjct: 186 WPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREA 245 Query: 223 ASRV--KITCDGYAVSSEIIVEASRKKCRIVEIPI 255 ASR + + +A E++ A K I EI + Sbjct: 246 ASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAV 280 >gb|AAG09682.1|AF183413_1 (AF183413) dolichyl-phosphate beta-glucosyltransferase [Homo sapiens] Length = 324 Score = 69.9 bits (168), Expect = 3e-11 Identities = 61/215 (28%), Positives = 103/215 (47%), Gaps = 29/215 (13%) Query: 67 IVMPAYNEEKTIGDVLDSLLRVFPREN---------IIVVDDGSRDRTREIA-------K 110 +V+P+YNEEK + ++D L + +IVVDDGS+D+T ++A Sbjct: 69 VVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQKYG 128 Query: 111 SKGVHVVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAE--- 167 S V V++ + NRG GGA+ GI + +G +I++ DADG D ++ K + + Sbjct: 129 SDKVRVITLVKNRGKGGAIRMGIFSS--RGEKILMA-DADGATKFPDVEKLEKGLNDLQP 185 Query: 168 --GKTDLAIGSRF---KGNLNQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNC 222 + +A GSR K ++ Q + + + + + I DTQ G + F+R Sbjct: 186 WPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREA 245 Query: 223 ASRV--KITCDGYAVSSEIIVEASRKKCRIVEIPI 255 ASR + + +A E++ A K I EI + Sbjct: 246 ASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAV 280 >gi|6325029 UDP-glucose:dolichyl-phosphate glucosyltransferase; Alg5p [Saccharomyces cerevisiae] >gi|728823|sp|P40350|ALG5_YEAST DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE >gi|1077101|pir||S48136 dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) [validated] - yeast (Saccharomyces cerevisiae) >gi|535141|emb|CAA54680.1| (X77573) dolichyl-phosphate beta-glucosyltransferase [Saccharomyces cerevisiae] >gi|1181261|emb|CAA64260.1| (X94561) dolichyl-phosphate beta-glucosyltransferase [Saccharomyces cerevisiae] >gi|1370470|emb|CAA97942.1| (Z73583) ORF YPL227c [Saccharomyces cerevisiae] Length = 334 Score = 69.1 bits (166), Expect = 6e-11 Identities = 73/248 (29%), Positives = 115/248 (45%), Gaps = 38/248 (15%) Query: 67 IVMPAYNEEKTI----GDVLDSLLRVF-PRENIIVVDDGSRDRTRE----IAKSK----- 112 +V+P+YNE I D + L + R I++VDDGS D T + I K + Sbjct: 77 VVIPSYNETGRILLMLTDAISFLKEKYGSRWEIVIVDDGSTDNTTQYCLKICKEQFKLNY 136 Query: 113 -GVHVVSHIINRGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAE---G 168 ++ NRG GGA+ G + K DADG D ++I +++ Sbjct: 137 EQFRIIKFSQNRGKGGAVRQGFLHIRGKYGLFA---DADGASKFSDVEKLIDAISKIETS 193 Query: 169 KTDL-------AIGSRFKGNLNQMPLVKR--VGNIAL---NLITAIFAFRYISDTQSGLR 216 TDL AIGSR +N ++KR + N + + + IF R I DTQ G + Sbjct: 194 STDLKTTKPAVAIGSRAH-MVNTEAVIKRSMIRNCLMYGFHTLVFIFGIRSIKDTQCGFK 252 Query: 217 AFSRNCASRV--KITCDGYAVSSEIIVEASRKKCRIVEIPITAVYTEYSMKKGTNVIEGI 274 F+R ++ + +G+ EI++ A RK+ +I EIPI+ + E K I+ I Sbjct: 253 LFNRAAILKIFPYLHTEGWIFDVEILILAIRKRIQIEEIPIS--WHEVDGSKMALAIDSI 310 Query: 275 KIALNLFV 282 K+A +L + Sbjct: 311 KMAKDLVI 318 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.321 0.140 0.387 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96821753 Number of Sequences: 2977 Number of extensions: 3971300 Number of successful extensions: 10051 Number of sequences better than 1.0e-10: 46 Number of HSP's better than 0.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 9949 Number of HSP's gapped (non-prelim): 47 length of query: 287 length of database: 189,106,746 effective HSP length: 57 effective length of query: 230 effective length of database: 154,992,987 effective search space: 35648387010 effective search space used: 35648387010 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 164 (68.3 bits)