BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1981 (PAB1981) DE:DOLICHYL-PHOSPHATE MANNOSE SYNTHASE RELATED PROTEIN (211 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75176 dolichyl-phosphate mannose synthase related protein ... 415 e-115 pir||D71038 hypothetical protein PH1596 - Pyrococcus horikoshii ... 296 2e-79 pir||D69148 dolichyl-phosphate mannose synthase related protein ... 158 4e-38 pir||G69148 dolichyl-phosphate mannose synthase related protein ... 155 4e-37 pir||F75058 dolichol-p-glucose synthetase PAB1411 - Pyrococcus a... 138 7e-32 sp|Q58619|YC22_METJA HYPOTHETICAL PROTEIN MJ1222 >gi|2128734|pir... 137 9e-32 pir||A71037 hypothetical protein PH1585 - Pyrococcus horikoshii ... 137 1e-31 gi|11497660 dolichol-P-glucose synthetase, putative [Archaeoglob... 136 3e-31 gi|11497940 dolichol-P-glucose synthetase, putative [Archaeoglob... 134 1e-30 pir||D75177 dolichyl-phosphate mannose synthase PAB1971 - Pyroco... 129 2e-29 sp|Q57964|Y544_METJA HYPOTHETICAL PROTEIN MJ0544 >gi|2127875|pir... 127 8e-29 pir||G69047 conserved hypothetical protein MTH136 - Methanobacte... 126 2e-28 gi|11497999 glycosyltransferase, putative [Archaeoglobus fulgidu... 122 4e-27 pir||B71154 hypothetical protein PH0433 - Pyrococcus horikoshii ... 120 1e-26 pir||E82657 dolichyl-phosphate mannose synthase related protein ... 115 6e-25 gi|11498189 dolichol-P-glucose synthetase, putative [Archaeoglob... 114 1e-24 pir||C69052 conserved hypothetical protein MTH1392 - Methanobact... 113 1e-24 pir||H70561 probable transferase - Mycobacterium tuberculosis (s... 106 2e-22 gb|AAF80640.1|AC069251_33 (AC069251) F2D10.6 [Arabidopsis thaliana] 104 1e-21 pir||G75191 dolichol-phosphate mannosyltransferase PAB2307 - Pyr... 103 2e-21 dbj|BAB06488.1| (AP001516) dolichyl-phosphate mannose synthase [... 102 4e-21 gb|AAF72730.1|AF265258_3 (AF265258) dolichyl-phosphate beta-gluc... 101 9e-21 pir||H71223 probable dolichol-phosphate mannosyltransferase - Py... 100 1e-20 gb|AAC98796.1| (AF007874) dolichol monophosphate mannose synthas... 100 2e-20 gb|AAF53817.1| (AE003663) CG10166 gene product [Drosophila melan... 100 2e-20 gb|AAG00234.1|AF283817_1 (AF283817) dolichol phosphate mannose s... 99 5e-20 pir||G70463 dolichol-phosphate mannosyltransferase - Aquifex aeo... 98 8e-20 emb|CAA18811.1| (AL023093) putative transferase [Mycobacterium l... 98 8e-20 gb|AAB63812.1| (AF009829) unknown [Mycobacterium bovis] 96 2e-19 pir||T33929 hypothetical protein Y66H1A.2 - Caenorhabditis elega... 96 4e-19 gi|6753670 dolichol-phosphate (beta-D) mannosyltransferase 1 [Mu... 94 9e-19 gb|AAG32629.1|AF102883_1 (AF102883) mannose phospho-dolichol syn... 94 1e-18 gi|4503363 dolichyl-phosphate mannosyltransferase polypeptide 1;... 94 2e-18 gi|6325029 UDP-glucose:dolichyl-phosphate glucosyltransferase; A... 93 2e-18 gb|AAD30975.1|AF121895_1 (AF121895) dolichol-phosphate-mannose s... 93 2e-18 pir||F70546 hypothetical protein Rv0539 - Mycobacterium tubercul... 92 5e-18 gb|AAK42146.1| Dolichyl-phosphate mannose synthase related prote... 90 1e-17 emb|CAB61668.1| (AL133213) putative glycosyl transferase. [Strep... 90 2e-17 gb|AAK41593.1| Dolichyl-phosphate mannose synthase related prote... 90 2e-17 pir||T40534 dolichyl-phosphate beta-gluco syltransferase - fissi... 89 3e-17 pir||T38633 dolichol monophosphate mannose synthase - fission ye... 89 5e-17 gb|AAC98797.1| (AF007875) dolichol monophosphate mannose synthas... 89 5e-17 gb|AAK43334.1| Dolichol-phosphate mannosyltransferase [Sulfolobu... 88 9e-17 pir||B75100 glycosyltransferase PAB1587 - Pyrococcus abyssi (str... 87 1e-16 gb|AAG19457.1| (AE005038) glycosyl transferase-like; Gtl [Haloba... 87 1e-16 emb|CAC11300.1| (AL445063) conserved hypothetical protein [Therm... 87 1e-16 pir||E69142 mannosyltransferase - Methanobacterium thermoautotro... 86 4e-16 gb|AAF52633.1| (AE003620) CG7870 gene product [Drosophila melano... 86 4e-16 pir||A71157 hypothetical protein PH0456 - Pyrococcus horikoshii ... 85 6e-16 pir||T34006 hypothetical protein H43I07.2 - Caenorhabditis elega... 85 6e-16 gb|AAF79605.1|AC027665_6 (AC027665) F5M15.10 [Arabidopsis thaliana] 85 6e-16 dbj|BAA19644.1| (AB002668) unnamed protein product [Actinobacill... 84 1e-15 pir||T34632 probable bi-functional transferase/deacetylase - Str... 83 2e-15 gi|7019323 dolichyl phosphate glucosyltransferase; Alg5, S. cere... 83 2e-15 gb|AAG09682.1|AF183413_1 (AF183413) dolichyl-phosphate beta-gluc... 83 2e-15 pir||G75005 hyaluronan synthase related PAB1314 - Pyrococcus aby... 82 4e-15 gb|AAC04771.1| (AF036677) PmrF [Salmonella typhimurium] 82 5e-15 emb|CAB76989.1| (AL159178) putative glycosyltransferase [Strepto... 82 7e-15 gb|AAG18896.1| (AE004992) dolichol-P-glucose synthetase; Dpg [Ha... 82 7e-15 pir||B75440 rfbJ protein/conserved hypothetical protein - Deinoc... 81 9e-15 sp|P77757|YFBF_ECOLI HYPOTHETICAL 36.3 KD PROTEIN IN AIS-PMRD IN... 80 3e-14 gb|AAC35924.1| (AF071085) putative glycosyl transferase [Enteroc... 80 3e-14 pir||T00571 dolichyl-phosphate beta-glucosyltransferase homolog ... 79 5e-14 gb|AAD01952.1| (AF033015) unknown [Listeria monocytogenes] 79 5e-14 pir||D72736 probable dolichol-phosphate-mannosyltransferase APE0... 78 6e-14 emb|CAC15463.1| (AJ294477) putative polyprenol phosphate mannosy... 78 1e-13 pir||T44819 dolichyl-phosphate beta-glucosyltransferase (EC 2.4.... 76 3e-13 gi|6325441 dolichol phosphate mannose synthase; Dpm1p [Saccharom... 75 7e-13 emb|CAC11893.1| (AL445065) dolichol-phosphate-mannosyltransferas... 75 7e-13 sp|P54856|DPM1_USTMA DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (DOL... 74 2e-12 pir||S70643 dolichyl-phosphate-mannose synthase precursor - Tryp... 73 2e-12 pir||S77381 rfbJ protein - Synechocystis sp. (strain PCC 6803) >... 73 2e-12 pir||T34985 probable sugar transferase - Streptomyces coelicolor... 73 3e-12 emb|CAB11300.1| (Z98604) hypothetical protein MLCB2052.02 [Mycob... 72 6e-12 emb|CAB72208.1| (AL138851) putative bi-functional transferase/de... 71 1e-11 gb|AAG19351.1| (AE005030) galactosyltransferase homolog; Gst [Ha... 70 2e-11 sp|O21943|GTRB_BPSF2 BACTOPRENOL GLUCOSYL TRANSFERASE >gi|246541... 69 3e-11 sp|O22007|GTRB_BPSF5 BACTOPRENOL GLUCOSYL TRANSFERASE >gi|246547... 69 3e-11 pir||B70945 hypothetical protein Rv2051c - Mycobacterium tubercu... 69 3e-11 gb|AAC69672.1| (AF019746) putative beta1,3-glucosyltransferase W... 69 3e-11 pir||D83201 probable glycosyl transferase PA3553 [imported] - Ps... 69 4e-11 pir||S76171 hypothetical protein - Synechocystis sp. (strain PCC... 68 7e-11 sp|P77293|GTRB_ECOLI BACTOPRENOL GLUCOSYL TRANSFERASE HOMOLOG FR... 68 7e-11 sp|Q9T1D6|GTRB_BPSFX BACTOPRENOL GLUCOSYL TRANSFERASE >gi|665275... 68 7e-11 emb|CAB81849.1| (AL161691) putative glucosyltransferase [Strepto... 68 7e-11 pir||D69769 cellulose synthase homolog ydaM - Bacillus subtilis ... 68 9e-11 gb|AAF09026.1| (AF139596) GtrBI [Shigella flexneri] 68 9e-11 >pir||A75176 dolichyl-phosphate mannose synthase related protein PAB1981 - Pyrococcus abyssi (strain Orsay) >gi|5457998|emb|CAB49488.1| (AJ248284) DOLICHYL-PHOSPHATE MANNOSE SYNTHASE RELATED PROTEIN [Pyrococcus abyssi] Length = 211 Score = 415 bits (1056), Expect = e-115 Identities = 211/211 (100%), Positives = 211/211 (100%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG Sbjct: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLV 120 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLV Sbjct: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLV 120 Query: 121 RKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEVLIKVAKKGARI 180 RKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEVLIKVAKKGARI Sbjct: 121 RKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEVLIKVAKKGARI 180 Query: 181 VEVPVSTRYDVETGHFRFRDIINFILTLLRY 211 VEVPVSTRYDVETGHFRFRDIINFILTLLRY Sbjct: 181 VEVPVSTRYDVETGHFRFRDIINFILTLLRY 211 >pir||D71038 hypothetical protein PH1596 - Pyrococcus horikoshii >gi|3258025|dbj|BAA30708.1| (AP000006) 215aa long hypothetical protein [Pyrococcus horikoshii] Length = 215 Score = 296 bits (749), Expect = 2e-79 Identities = 144/210 (68%), Positives = 174/210 (82%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGK 61 K+SVIIPAYNEE+RIG VL IP+FV+EVIVVDDGS D T+ VA G VIRL +N GK Sbjct: 6 KISVIIPAYNEERRIGNVLKGIPDFVDEVIVVDDGSSDGTSKVAMELGATVIRLNKNSGK 65 Query: 62 GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLVR 121 GAAMREG+K + GDIIVFMDADGQH+PKEI +++ PI++G AD VIG+R+I GKRP+ R Sbjct: 66 GAAMREGLKISTGDIIVFMDADGQHNPKEIYRLVKPIVEGRADLVIGRRIITRGKRPMSR 125 Query: 122 KLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEVLIKVAKKGARIV 181 K+SNFITT LI K ++K+ DTQSGFRAI+REF+P IES+RYEVETEVLIK KKGARI+ Sbjct: 126 KISNFITTRLITLKTRKKILDTQSGFRAIRREFVPVIESDRYEVETEVLIKAIKKGARIL 185 Query: 182 EVPVSTRYDVETGHFRFRDIINFILTLLRY 211 EVP+STRYDVETGHF+ DI F+ L++Y Sbjct: 186 EVPISTRYDVETGHFKMIDIFRFLFALIKY 215 >pir||D69148 dolichyl-phosphate mannose synthase related protein 2 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621435|gb|AAB84880.1| (AE000823) dolichyl-phosphate mannose synthase related protein [Methanobacterium thermoautotrophicum] Length = 291 Score = 158 bits (396), Expect = 4e-38 Identities = 88/196 (44%), Positives = 117/196 (58%), Gaps = 4/196 (2%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 M++ +IPA+NEE IG V+ E V+EVIVVDDGS D TA VA+ G RVIR N G Sbjct: 1 MRIVAVIPAFNEEVAIGSVVLLTGEHVDEVIVVDDGSADRTAHVAEMAGARVIRHHRNLG 60 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVI--KAGKRP 118 KGAA++ G + A D+IV +DAD QH+P EIPK++ PI++G+AD V G R + + P Sbjct: 61 KGAALKTGFEAADADVIVTLDADAQHNPAEIPKLVEPILRGEADVVNGSRYLHGRDENTP 120 Query: 119 LVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPD--IESERYEVETEVLIKVAKK 176 R++ I + DTQSGFRA +P + VE+E+L A+ Sbjct: 121 RYRRVGQKILDRATNISTGLDITDTQSGFRAFSSASIPHFRFRDPGFVVESEMLADAAEA 180 Query: 177 GARIVEVPVSTRYDVE 192 G RIVEV V RYDV+ Sbjct: 181 GLRIVEVEVGVRYDVD 196 >pir||G69148 dolichyl-phosphate mannose synthase related protein 1 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621438|gb|AAB84883.1| (AE000823) dolichyl-phosphate mannose synthase related protein [Methanobacterium thermoautotrophicum] Length = 248 Score = 155 bits (388), Expect = 4e-37 Identities = 89/218 (40%), Positives = 133/218 (60%), Gaps = 11/218 (5%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 M+V +IPA+NEE+ + V+ E +VI+VDDGS D TA + + G RVI P+N G Sbjct: 23 MRVVTVIPAFNEERTVESVVRGALEH-GDVILVDDGSTDRTAALGEEAGARVISHPKNLG 81 Query: 61 KGAAMREGIKHAKG---DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAG-- 115 KGAA++ GI+ A G D+IVFMDADGQHDP IP++ + + G DF+IG R I+ Sbjct: 82 KGAALKTGIREALGGDYDVIVFMDADGQHDPSLIPELASAVNGG--DFIIGSRFIRNNHD 139 Query: 116 KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREF---LPDIESERYEVETEVLIK 172 PL R+LSN ITT ++R ++ D+QSGFRAI + + +I + Y E+E + + Sbjct: 140 SMPLHRQLSNRITTWILRLATGYRITDSQSGFRAISARYAHLILEIPYDDYVYESEAICE 199 Query: 173 VAKKGARIVEVPVSTRYDVETGHFRFRDIINFILTLLR 210 ++ RI EVP++ Y E + D++ +I ++R Sbjct: 200 TSRHRLRIAEVPITCTYGDEKSYIGVGDVLQYIRFIVR 237 >pir||F75058 dolichol-p-glucose synthetase PAB1411 - Pyrococcus abyssi (strain Orsay) >gi|5458876|emb|CAB50363.1| (AJ248287) DOLICHOL-P-GLUCOSE SYNTHETASE [Pyrococcus abyssi] Length = 378 Score = 138 bits (343), Expect = 7e-32 Identities = 84/197 (42%), Positives = 120/197 (60%), Gaps = 12/197 (6%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEV-----IVVDDGSKDNTADVAKRFGVRVIRL 55 ++VSVI+P NEEK + KV+ +I E + ++ I+V D S D T ++A+ G +VIR Sbjct: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIR- 66 Query: 56 PENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV---I 112 + +G G A EG K AKG IV MD DG +DPKEIPK++ + K ADFVIG R+ I Sbjct: 67 QKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKI 126 Query: 113 KAGKRP-LVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLP--DIESERYEVETEV 169 + G P L R + N + T ++ K KV D SGFRAIKR+ L ++ E +E+ Sbjct: 127 EPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEM 186 Query: 170 LIKVAKKGARIVEVPVS 186 +I+ AK G +I EVP++ Sbjct: 187 IIEAAKAGLKIAEVPIT 203 >sp|Q58619|YC22_METJA HYPOTHETICAL PROTEIN MJ1222 >gi|2128734|pir||E64452 conserved hypothetical protein MJ1222 - Methanococcus jannaschii >gi|1591853|gb|AAB99226.1| (U67563) dolichol-P-glucose synthetase isolog [Methanococcus jannaschii] Length = 243 Score = 137 bits (342), Expect = 9e-32 Identities = 78/199 (39%), Positives = 118/199 (59%), Gaps = 11/199 (5%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIP-EFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 ++ V++PA+NEEK IG+ L + E ++VVDDGS D T+++AK+ GV V R NRG Sbjct: 18 EIFVVVPAFNEEKMIGETLKNLKKEGYKNIVVVDDGSMDKTSEIAKKEGVIVCRHILNRG 77 Query: 61 KGAAMREGIKHA---KGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGK- 116 G A+ GIK A K II+ DADGQH PK++ K++ P++ D IG R++ + Sbjct: 78 LGGALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLFEGYDMAIGSRMMDKNEL 137 Query: 117 --RPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIK----REFLPDIESERYEVETEVL 170 PLV+++ NF + V D+QSG RA ++ + D++S+RYEV +E + Sbjct: 138 KNMPLVKRIGNFGLNFITYLMGGYFVTDSQSGLRAFSYEAAKKIIGDLKSDRYEVSSEFI 197 Query: 171 IKVAKKGARIVEVPVSTRY 189 I K G ++ EVP+ T Y Sbjct: 198 ILAKKHGLKLKEVPIKTIY 216 >pir||A71037 hypothetical protein PH1585 - Pyrococcus horikoshii >gi|3258014|dbj|BAA30697.1| (AP000006) 313aa long hypothetical protein [Pyrococcus horikoshii] Length = 313 Score = 137 bits (341), Expect = 1e-31 Identities = 86/223 (38%), Positives = 126/223 (55%), Gaps = 14/223 (6%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFV--NEVIVVDDGSKDNTADVAKRFGVRVIRLPENR 59 K +++PAYNEEK IG VL + + N +IVVDDGSKD T ++AK GV VI NR Sbjct: 90 KTYIVMPAYNEEKTIGSVLDSLLKVFKPNNIIVVDDGSKDKTREIAKSKGVHVISHIINR 149 Query: 60 GKGAAMREGIKHA---KGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVI-KAG 115 G G A+ GI +A +IIV DADGQH ++ K+I P+++G AD IG R G Sbjct: 150 GLGGALGTGIYYALMRGAEIIVTFDADGQHLLEDALKVIKPVVEGRADLAIGSRFKGDIG 209 Query: 116 KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIE--SERYEVETEVLIKV 173 + PLV+++ N + T+ + V D+QSG RA R I+ + Y V +E++++ Sbjct: 210 QMPLVKRIGNIVLNTITAVFAMRYVTDSQSGLRAFSRACASKIKITCDGYAVSSEIIVEA 269 Query: 174 AKKGARIVEVPVS---TRYDVETGHFRFRDI---INFILTLLR 210 ++ +IVEVP+ T Y ++ G I IN +L + R Sbjct: 270 SRGKCKIVEVPIKAVYTEYSMKKGTNVMEGIKIAINLLLDIFR 312 >gi|11497660 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] >gi|7483292|pir||G69254 dolichol-P-glucose synthetase homolog - Archaeoglobus fulgidus >gi|2650613|gb|AAB91190.1| (AE001104) dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] Length = 369 Score = 136 bits (338), Expect = 3e-31 Identities = 86/210 (40%), Positives = 122/210 (57%), Gaps = 14/210 (6%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPE--FVNEVIVVDDGSKDNTADVAKRFGVRVIRLPEN 58 MKVS+++P +E+ I KV+ + F E+IVVDD S D T ++A++ G +VIR Sbjct: 1 MKVSIVLPTKDEQNSIEKVVRDCLSLGFEKEIIVVDD-SADRTPEIAEKLGCKVIR--GV 57 Query: 59 RGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRP 118 +G G A EG +H+ GDIIV +DADG +D EIP++I PI+KG+AD VIG R K P Sbjct: 58 KGYGRAFLEGFRHSSGDIIVMLDADGSYDALEIPRLIEPIVKGEADLVIGSR-FKGKIMP 116 Query: 119 LV-----RKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIE--SERYEVETEVLI 171 R + N + T L K K+ D SG RA++++ L I+ E TE+++ Sbjct: 117 KAMPWHHRYVGNPVLTKLTNLLFKTKLSDVHSGMRALRKDALAKIDPVCPGMEFATELVL 176 Query: 172 KVAKKGARIVEVPVSTRYDVETGHFR-FRD 200 K A KG RIVEVP++ + R FRD Sbjct: 177 KAAIKGLRIVEVPITYHPRIGFSKLRSFRD 206 >gi|11497940 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] >gi|7483293|pir||H69290 dolichol-P-glucose synthetase homolog - Archaeoglobus fulgidus >gi|2650309|gb|AAB90908.1| (AE001082) dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] Length = 371 Score = 134 bits (333), Expect = 1e-30 Identities = 82/191 (42%), Positives = 115/191 (59%), Gaps = 10/191 (5%) Query: 3 VSVIIPAYNEEKRIGKVLAE-IPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGK 61 ++V++P NEEK I +++ + + V E+IVVDD S D+T ++A++ G RVI+ +G Sbjct: 2 ITVVLPTKNEEKAIEEIVKKCLVVGVKEIIVVDD-STDSTPEIAEKLGCRVIK--NVKGY 58 Query: 62 GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV---IKAGKRP 118 G A EG+KHA GDIIV MDADG +DP EIPK++ PI++ +AD VIG R I G P Sbjct: 59 GNAYLEGLKHASGDIIVLMDADGTYDPAEIPKLVEPILRDEADVVIGSRFKGKIMPGAMP 118 Query: 119 LVRK-LSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLP--DIESERYEVETEVLIKVAK 175 K L N + T L D SGFRAIK+ L D++ E TE ++K Sbjct: 119 WHHKYLGNPLLTKLTNFLFGTGFSDVHSGFRAIKKSSLSQLDLKCPGMEFATEFVLKTTM 178 Query: 176 KGARIVEVPVS 186 G R++EVPV+ Sbjct: 179 SGLRLLEVPVT 189 >pir||D75177 dolichyl-phosphate mannose synthase PAB1971 - Pyrococcus abyssi (strain Orsay) >gi|5458009|emb|CAB49499.1| (AJ248284) DOLICHYL-PHOSPHATE MANNOSE SYNTHASE [Pyrococcus abyssi] Length = 287 Score = 129 bits (322), Expect = 2e-29 Identities = 77/205 (37%), Positives = 117/205 (56%), Gaps = 11/205 (5%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFV--NEVIVVDDGSKDNTADVAKRFGVRVIRLPEN 58 MK +++PAYNEEK IG VL + +IVVDDGS+D T ++AK GV V+ N Sbjct: 63 MKTYIVMPAYNEEKTIGDVLDSLLRVFPRENIIVVDDGSRDRTREIAKSKGVHVVSHIIN 122 Query: 59 RGKGAAMREGIKHA--KG-DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVI-KA 114 RG G A+ GI++A KG +I+V DADGQH ++ ++I P+ +G D IG R Sbjct: 123 RGLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNL 182 Query: 115 GKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLP--DIESERYEVETEVLIK 172 + PLV+++ N + + + DTQSG RA R I + Y V +E++++ Sbjct: 183 NQMPLVKRVGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEIIVE 242 Query: 173 VAKKGARIVEVPVS---TRYDVETG 194 ++K RIVE+P++ T Y ++ G Sbjct: 243 ASRKKCRIVEIPITAVYTEYSMKKG 267 >sp|Q57964|Y544_METJA HYPOTHETICAL PROTEIN MJ0544 >gi|2127875|pir||H64367 dolichyl-phosphate mannose synthase - Methanococcus jannaschii >gi|1592295|gb|AAB98538.1| (U67504) dolichyl-phosphate mannose synthase [Methanococcus jannaschii] Length = 229 Score = 127 bits (317), Expect = 8e-29 Identities = 84/204 (41%), Positives = 117/204 (57%), Gaps = 19/204 (9%) Query: 6 IIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRF------GVRVIRLPENR 59 IIPA+NEEK I KVL ++ + + +VVDDGSKDNT+ + + F V +IR +N Sbjct: 4 IIPAFNEEKNILKVLKDLEKLRVDAVVVDDGSKDNTSKIVEEFAKKAKINVYLIRNEKNE 63 Query: 60 GKGAAMREGIKHA----KGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAG 115 GK A+ +G K A K I+++D D QH P +IPK++ + +AD V G R K Sbjct: 64 GKAKAIEKGTKFALSLNKYKYIIYIDGDYQHKPMDIPKLLKKLEDTNADAVFGIRKYK-- 121 Query: 116 KRPLVRKLSNFITT------TLIRAKIKQKVDDTQSGFRAIKREFLPDIE-SERYEVETE 168 PL R++SNF + LI +K D Q GFR IK EFL D++ + Y VE Sbjct: 122 HIPLHRQISNFFASILTSLAVLIYSKRFYFFRDVQCGFRIIKAEFLKDMKFGDGYAVEHF 181 Query: 169 VLIKVAKKGARIVEVPVSTRYDVE 192 + +++AKKGA+IVE VS Y E Sbjct: 182 IALQLAKKGAKIVEEYVSVEYHDE 205 >pir||G69047 conserved hypothetical protein MTH136 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621176|gb|AAB84642.1| (AE000802) dolichyl-phosphate mannose synthase [Methanobacterium thermoautotrophicum] Length = 220 Score = 126 bits (314), Expect = 2e-28 Identities = 77/201 (38%), Positives = 115/201 (56%), Gaps = 12/201 (5%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADV-----AKRFGVRVIRLPE 57 V+V++P YNEEK + V+ + + VI VDDGS+D+T ++ ++R G+ V Sbjct: 12 VAVVVPVYNEEKTVAGVIESLLDRGYRVIAVDDGSRDSTPEILAGIASERDGLSVYTHVI 71 Query: 58 NRGKGAAMREGIKHAKGD---IIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKA 114 NRG G A+R G++ A + IV DADGQHDP +I +I P++KG+AD VIG R Sbjct: 72 NRGLGTALRTGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEADVVIGSR--DF 129 Query: 115 GKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAI--KREFLPDIESERYEVETEVLIK 172 + PL R L N + L +V D+QSG RA + + DI+S Y V +E++ + Sbjct: 130 SEMPLSRSLGNTLMNLLTLLFYGCRVSDSQSGLRAFTARAASVIDIKSRGYGVSSEIIGE 189 Query: 173 VAKKGARIVEVPVSTRYDVET 193 + + G R+ EV + T Y ET Sbjct: 190 IHRNGLRMREVTIKTIYTPET 210 >gi|11497999 glycosyltransferase, putative [Archaeoglobus fulgidus] >gi|7445538|pir||C69298 glycosyltransferase homolog - Archaeoglobus fulgidus >gi|2650247|gb|AAB90850.1| (AE001078) glycosyltransferase, putative [Archaeoglobus fulgidus] Length = 305 Score = 122 bits (302), Expect = 4e-27 Identities = 69/192 (35%), Positives = 109/192 (55%), Gaps = 5/192 (2%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 M V+V+IP NEE+ IG+V+ + V+V+D SKD T ++A+ G V+ + +G Sbjct: 1 MDVTVVIPTLNEEEAIGEVVEGFAKRGFRVLVIDGNSKDRTREIAREKGAEVV-IQSGKG 59 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLV 120 KG A+ E + DI+V +D DG + P+E+ +++ PI +G AD VIG R K Sbjct: 60 KGQAVAEAFEIVDSDILVLVDGDGTYLPEEVYRLLEPIKEGGADHVIGNRFASFEKGAFT 119 Query: 121 R--KLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER--YEVETEVLIKVAKK 176 R + N + R ++ D SG+RA+K+E +E + +EVETE+ ++ K Sbjct: 120 RLNLIGNKLLNMFFRLAYGVELRDILSGYRALKKEVYKSVELTKPGFEVETELTVETLAK 179 Query: 177 GARIVEVPVSTR 188 G RIVEVP++ R Sbjct: 180 GFRIVEVPITYR 191 >pir||B71154 hypothetical protein PH0433 - Pyrococcus horikoshii >gi|3256836|dbj|BAA29519.1| (AP000002) 304aa long hypothetical protein [Pyrococcus horikoshii] Length = 304 Score = 120 bits (298), Expect = 1e-26 Identities = 68/189 (35%), Positives = 109/189 (56%), Gaps = 6/189 (3%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEF-VNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGK 61 V+++IP NEE+ IG V+ E + N ++V+D S D T ++AK G +V+ L +GK Sbjct: 10 VTILIPTKNEEEGIGWVIEEFKKLGYNNILVIDGHSTDRTREIAKEKGAKVV-LQTGKGK 68 Query: 62 GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV--IKAGKRPL 119 G A+ E K +++V +D DG +DPK++ K++ PI +G A+ VIG R+ + G Sbjct: 69 GQAVAEAFKLIDSEVVVLIDGDGTYDPKDVEKMLEPIRRGIAEHVIGNRLENFEDGAFTR 128 Query: 120 VRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER--YEVETEVLIKVAKKG 177 + + N I L R V D SG+RA +E +E ++ +EVETE+ ++ KG Sbjct: 129 LNLIGNKIFNALFRFLYGVPVYDMLSGYRAFTKELYKSVELKKHGFEVETELTVETVAKG 188 Query: 178 ARIVEVPVS 186 RI EVP++ Sbjct: 189 FRIAEVPIN 197 >pir||E82657 dolichyl-phosphate mannose synthase related protein XF1638 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106693|gb|AAF84447.1|AE003990_10 (AE003990) dolichyl-phosphate mannose synthase related protein [Xylella fastidiosa] Length = 274 Score = 115 bits (284), Expect = 6e-25 Identities = 74/212 (34%), Positives = 109/212 (50%), Gaps = 14/212 (6%) Query: 4 SVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGKGA 63 ++IIPA NE I KV+ + + VIVVDDGS D TA+ + +IR P+ RGKGA Sbjct: 12 AIIIPALNEALSIRKVITDALAYCPHVIVVDDGSDDGTANCISDLPIILIRHPQRRGKGA 71 Query: 64 AMREGIKHAKG---DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLV 120 A+R G A ++ MD DGQH + P+++A +IG R+ K ++P + Sbjct: 72 ALRSGFAAATQLGVQGVITMDGDGQHSAADFPRLLAAANYHPGCVIIGARLRKRSEQPWI 131 Query: 121 RKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREF--LPDIESERYEVETEVLIKVAKK-G 177 R++ N I ++ DTQSG R LPD+ E + E ++LI A++ G Sbjct: 132 RRIGNHFGDWGISWGCGCRIVDTQSGQRFYPASVFTLPDVSGEDFVFEAQLLISAARQAG 191 Query: 178 ARIVEVPVSTRYDV-------ETGHFRF-RDI 201 AR++ VP+ RY HFR RD+ Sbjct: 192 ARMIAVPIEARYSTPHSPNVFRKSHFRMVRDL 223 >gi|11498189 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] >gi|7483291|pir||E69322 dolichol-P-glucose synthetase homolog - Archaeoglobus fulgidus >gi|2650038|gb|AAB90655.1| (AE001064) dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus] Length = 581 Score = 114 bits (282), Expect = 1e-24 Identities = 69/227 (30%), Positives = 119/227 (52%), Gaps = 17/227 (7%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFG----- 49 MK+S+++PAYNE KR+ + E+ + E+I+ +DGSKD T +A Sbjct: 54 MKISIVLPAYNEAKRLRGAVEEVIKAAEKTGYDFEIIIAEDGSKDGTDRIAAELAASNPR 113 Query: 50 VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 ++ + E G+G A+ A GD++V+MD D D + +++ II DF G Sbjct: 114 IKHLHSDERLGRGRALMNAFSKASGDVVVYMDVDLATDLSHLKELVDAIIVEGYDFSTGS 173 Query: 110 RVIKAGK--RPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESE----RY 163 R++K + RP R++++ L+R + K+ D Q GF+A +R+ + D+ E + Sbjct: 174 RLMKESQTDRPAKREIASRGYNFLVRLFLGSKLHDHQCGFKAFRRDLILDLGKEVKDNHW 233 Query: 164 EVETEVLIKVAKKGARIVEVPVSTRYDVETGHFRFRDIINFILTLLR 210 +TEVL+ K+G R+ E+PV ++ ET +DI+ +LR Sbjct: 234 FWDTEVLVLAQKRGYRVKEIPVRWKHGGETKVAFGKDILYMFSQILR 280 >pir||C69052 conserved hypothetical protein MTH1392 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622503|gb|AAB85869.1| (AE000902) dolichyl-phosphate mannoosyltransferase related protein [Methanobacterium thermoautotrophicum] Length = 564 Score = 113 bits (281), Expect = 1e-24 Identities = 75/188 (39%), Positives = 109/188 (57%), Gaps = 11/188 (5%) Query: 3 VSVIIPAYNEEKRIGKVL--AEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 VSV+IPA NEEK +G V+ A + V+EVIVVDDGS DNTA A+ G VIR NRG Sbjct: 25 VSVVIPALNEEKTVGSVIEAARKSDMVDEVIVVDDGSTDNTAGAAEDAGATVIRHTSNRG 84 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQH-DPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPL 119 KGAA++ G KH++GDI+VF+DAD ++ ++I ++I PII G AD + KAG Sbjct: 85 KGAALKTGFKHSRGDIVVFVDADLENMTTEKIERMIKPIITGRADLTKTRFRRKAG---- 140 Query: 120 VRKLSNFITTTLIRAKIKQ-KVDDTQSGFRAIKREFLPDIE-SERYEVETEVLIKVAKKG 177 +++ L++ + K + SG A KR L ++ E Y V+ +++ G Sbjct: 141 --RVTELTAKPLLKFFFPEIKFEQPLSGQFAAKRSALEKMKFEEDYGVDVGIVLDADVLG 198 Query: 178 ARIVEVPV 185 + EV + Sbjct: 199 LTVREVDI 206 >pir||H70561 probable transferase - Mycobacterium tuberculosis (strain H37RV) >gi|2105063|emb|CAB08827.1| (Z95436) hypothetical protein Rv3631 [Mycobacterium tuberculosis] Length = 241 Score = 106 bits (262), Expect = 2e-22 Identities = 64/199 (32%), Positives = 102/199 (51%), Gaps = 12/199 (6%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGKG 62 V V+IPA+NE IGKV+ ++ + V+ VDDGS D T D+A+R G ++R P N G+G Sbjct: 14 VWVVIPAFNEAAVIGKVVTDVRSVFDHVVCVDDGSTDGTGDIARRSGAHLVRHPINLGQG 73 Query: 63 AAMREGIKHAK----GDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV------I 112 AA++ GI++A+ + D DGQH K++ ++ + GD D VIG R Sbjct: 74 AAIQTGIEYARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGAGDVDVVIGTRFGRPVGKA 133 Query: 113 KAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLP--DIESERYEVETEVL 170 A + PL++++ L R + + DT +G R + +I TE + Sbjct: 134 SASRPPLMKRIVLQTGARLSRRGRRLGLTDTNNGLRVFNKTVADGLNITMSGMSHATEFI 193 Query: 171 IKVAKKGARIVEVPVSTRY 189 + +A+ R+ E PV Y Sbjct: 194 MLIAENHWRVAEEPVEVLY 212 >gb|AAF80640.1|AC069251_33 (AC069251) F2D10.6 [Arabidopsis thaliana] Length = 246 Score = 104 bits (256), Expect = 1e-21 Identities = 70/203 (34%), Positives = 104/203 (50%), Gaps = 18/203 (8%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN----EVIVVDDGSKDNTADVAKR----FGVRVI 53 K S+IIP YNE I ++ I + + E+IVVDDGS D T ++ K+ +G I Sbjct: 14 KYSIIIPTYNERLNIAIIVYLIFKHLRDVDFEIIVVDDGSPDGTQEIVKQLQQLYGEDRI 73 Query: 54 RL---PENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 L + G G A G+KHA GD +V MDAD H PK +P I ++ +A V G R Sbjct: 74 LLRARAKKLGLGTAYIHGLKHATGDFVVIMDADLSHHPKYLPSFIKKQLETNASIVTGTR 133 Query: 111 VIKAG---KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI----ESERY 163 +K G L+RKL++ L + + V D FR K+ L D+ S+ Y Sbjct: 134 YVKGGGVHGWNLMRKLTSRGANVLAQTLLWPGVSDLTGSFRLYKKSALEDVISSCVSKGY 193 Query: 164 EVETEVLIKVAKKGARIVEVPVS 186 + E++++ +KG I EVP++ Sbjct: 194 VFQMEMIVRATRKGYHIEEVPIT 216 >pir||G75191 dolichol-phosphate mannosyltransferase PAB2307 - Pyrococcus abyssi (strain Orsay) >gi|5457491|emb|CAB48982.1| (AJ248283) DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE [Pyrococcus abyssi] Length = 362 Score = 103 bits (254), Expect = 2e-21 Identities = 75/227 (33%), Positives = 125/227 (55%), Gaps = 21/227 (9%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN----EVIVVDDGSKDNT----ADVAKRFGVRV 52 MKVSVI+P YNE + + ++ + I + + E+IVVDD S D T +++ + V+V Sbjct: 12 MKVSVIVPTYNERENLEELFSRIDKALKDYDYEIIVVDDDSPDETWKKAQELSSVYPVKV 71 Query: 53 IRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVI 112 IR +G +A+ G K A GD+ V MDAD QH P+ IP+++ I +G AD I R + Sbjct: 72 IRRINEKGLSSAVIRGFKEASGDVFVVMDADLQHPPEVIPELLKRIKEG-ADLAIASRYV 130 Query: 113 KAGK---RPLVRKLSNFITTTLIRAKIK--QKVDDTQSGFRAIKREFLPDIESE--RYEV 165 K G+ PL RKL + + R + + + D SGF A+KR + ++ +++ Sbjct: 131 KGGRVENWPLYRKLISKGAIMIARVALPKIRSIKDPVSGFFALKRNVVDNVNLNPIGFKI 190 Query: 166 ETEVLIKVAKKGARIVEVPVS--TRYDVETGHFRFRDIINFILTLLR 210 E+LIK + +R+ EVP + TR E+ + + ++N++ + R Sbjct: 191 LLEILIK--GRYSRVEEVPFTFGTRLSGES-KLKGKTMLNYLRHVYR 234 >dbj|BAB06488.1| (AP001516) dolichyl-phosphate mannose synthase [Bacillus halodurans] Length = 222 Score = 102 bits (251), Expect = 4e-21 Identities = 70/201 (34%), Positives = 109/201 (53%), Gaps = 13/201 (6%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNE--VIVVDDGSKDNTADVAKRFGVRVIRLPENR 59 ++SV+IPAYNE + + + I + E VIVVDDGS D+T +A+R + LP N+ Sbjct: 3 RISVVIPAYNEASDLPQTIQGIRDLSLECEVIVVDDGSVDDTKKIAERLADITVALPVNQ 62 Query: 60 GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKR-- 117 GKG A+ EG K A+G IV +DAD E+ ++ P++ +AD VIG + K+ Sbjct: 63 GKGQALMEGWKRAEGTHIVMLDADLGSTSSEMAHLLPPLLTNEADLVIGMLPTHSSKKGF 122 Query: 118 PLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER---YEVETEVLIKVA 174 LV+K + I + + SG RA R +LP + E + VET++L+ Sbjct: 123 GLVKKRAQ----QYIAKRTGAFLTAPLSGQRAFHRRWLPSLLEENVQGFGVETQMLLHFL 178 Query: 175 KKGARIVEVP--VSTRYDVET 193 +GA + E+P ++ RY +T Sbjct: 179 LRGAVVKEIPTLMAHRYTGKT 199 >gb|AAF72730.1|AF265258_3 (AF265258) dolichyl-phosphate beta-glucosyltransferase [Rhodococcus sp. S9] Length = 342 Score = 101 bits (248), Expect = 9e-21 Identities = 67/205 (32%), Positives = 105/205 (50%), Gaps = 27/205 (13%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNE-------VIVVDDGSKDNTADVAKRF-----GV 50 + V+IP YNEE + K + + E + E + + D+ S D T VA R GV Sbjct: 22 LEVVIPVYNEEADLEKCIRRLHEHLEERIPFRSRITIADNASNDGTLAVAHRLADEIDGV 81 Query: 51 RVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG-- 108 RV L E +G+G A++ + D++ +MD D D + ++AP++ G +D IG Sbjct: 82 RVHHLDE-KGRGRALKAVWLASDADVVAYMDVDLSTDLNALMPLVAPLLSGHSDLAIGSR 140 Query: 109 ----KRVIKAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIK----REFLPDIES 160 RV++ KR L+ + N I T +RA+ D Q GF+A++ R+ LP +E Sbjct: 141 LNRSSRVVRGVKRELISRSYNLILRTSLRARF----SDAQCGFKAMRTDVARQLLPLVED 196 Query: 161 ERYEVETEVLIKVAKKGARIVEVPV 185 + +TE+L+ K G RI EVPV Sbjct: 197 TGWFFDTELLVIAEKVGLRIHEVPV 221 >pir||H71223 probable dolichol-phosphate mannosyltransferase - Pyrococcus horikoshii >gi|3256436|dbj|BAA29119.1| (AP000001) 353aa long hypothetical dolichol-phosphate mannosyltransferase [Pyrococcus horikoshii] Length = 353 Score = 100 bits (247), Expect = 1e-20 Identities = 77/228 (33%), Positives = 121/228 (52%), Gaps = 23/228 (10%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN----EVIVVDDGSKDNT----ADVAKRFGVRV 52 MKVS+I+P YNE + ++ + I + E+I+VDD S D T +++K + V+V Sbjct: 1 MKVSIIVPTYNERDNLEELFSRISSALKGYDYEIIIVDDDSPDKTWEKAMELSKLYPVKV 60 Query: 53 IRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVI 112 IR +G +A+ G A GD+ V MDAD QH P+ IP ++ I KG+ D I R + Sbjct: 61 IRRVNEKGLSSAVIRGFSEASGDVFVVMDADLQHPPEVIPSLLREIEKGN-DIAIASRYV 119 Query: 113 KAGK---RPLVRKLSN---FITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESE--RYE 164 K GK P R+L + I L KI + D SGF A+KR + ++ ++ Sbjct: 120 KGGKVENWPFYRRLISRGAIIIGRLALPKI-AGIKDPVSGFFALKRSVVEGVKLNPIGFK 178 Query: 165 VETEVLIKVAKKGARIVEVP--VSTRYDVETGHFRFRDIINFILTLLR 210 + E+LIK K +R+ EVP STR E+ + + ++N++ + R Sbjct: 179 ILMEILIK--GKYSRVTEVPFTFSTRKFGES-KLKGKTMVNYLRHVYR 223 >gb|AAC98796.1| (AF007874) dolichol monophosphate mannose synthase [Caenorhabditis briggsae] Length = 242 Score = 100 bits (246), Expect = 2e-20 Identities = 71/207 (34%), Positives = 102/207 (48%), Gaps = 26/207 (12%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN----EVIVVDDGSKDNTADVAK----RFGVRVI 53 K S+I+P YNE++ + + I +++ E+I+VDD S D T DVAK +G I Sbjct: 9 KYSIILPTYNEKENLPICIWLIEKYLKGISYEIIIVDDASPDGTQDVAKLLEKEYGENKI 68 Query: 54 RLPENRGK---GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 + GK G A G+ A+G+ I+ MDAD H PK IP++IA K D V G R Sbjct: 69 LIKPRAGKLGLGTAYSHGLSFARGEFIILMDADLSHHPKFIPEMIALQQKYKLDIVTGTR 128 Query: 111 VIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER- 162 G KR + K +NF+ L + V D FR K+E L + +E Sbjct: 129 YKNGGGVSGWDLKRKTISKGANFLAQFL----LNPGVSDLTGSFRLYKKEVLATLIAESV 184 Query: 163 ---YEVETEVLIKVAKKGARIVEVPVS 186 Y + E++ + K G RI EVP+S Sbjct: 185 SKGYVFQMEMMFRAKKSGYRIGEVPIS 211 >gb|AAF53817.1| (AE003663) CG10166 gene product [Drosophila melanogaster] Length = 241 Score = 99.8 bits (245), Expect = 2e-20 Identities = 70/209 (33%), Positives = 104/209 (49%), Gaps = 28/209 (13%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFGV----- 50 K S+++P YNE+ + ++ I +++ EVIV+DDGS D T DVAK Sbjct: 7 KYSILMPTYNEKDNLPIIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYGED 66 Query: 51 RVIRLPENR--GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 +++ P G G A GIKHA GD IV +DAD H PK IP+ I +G+ D V G Sbjct: 67 KIVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIVSG 126 Query: 109 KRVIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFL----PD 157 R G KR L+ + +NF++ L+R D FR K++ L Sbjct: 127 TRYAGNGGVFGWDFKRKLISRGANFLSQVLLR----PNASDLTGSFRLYKKDVLEKCIAS 182 Query: 158 IESERYEVETEVLIKVAKKGARIVEVPVS 186 S+ Y + E+L++ + G I EVP++ Sbjct: 183 CVSKGYVFQMEMLVRARQHGYTIAEVPIT 211 >gb|AAG00234.1|AF283817_1 (AF283817) dolichol phosphate mannose synthase [Schistosoma mansoni] Length = 237 Score = 98.7 bits (242), Expect = 5e-20 Identities = 78/232 (33%), Positives = 113/232 (48%), Gaps = 31/232 (13%) Query: 4 SVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRF----GVRVI 53 S+I+P YNE++ + + I + +N E+I+VDD S D T +VAK+ G I Sbjct: 5 SIILPTYNEKENLPIITWIIDKVMNKSGFPYELIIVDDNSPDGTGEVAKKLQSILGENKI 64 Query: 54 RLPENRGK---GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 L GK G+A G+K AKGD I+ MDAD H PK IP+ I + D D V G R Sbjct: 65 ILKPRSGKLGLGSAYLHGLKFAKGDFIIIMDADLSHHPKFIPEFIKLQKQHDYDVVTGTR 124 Query: 111 VIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI----E 159 G KR L+ + +N+I L+R K D FR K+ L D+ Sbjct: 125 YASNGGVSGWDLKRKLISRTANYIAQVLLR----PKASDLTGSFRLYKKAVLQDLVSRCT 180 Query: 160 SERYEVETEVLIKVAKKGARIVEVPVSTRYDVETGHFRF--RDIINFILTLL 209 S Y + E+++ + G +I EV + T D G + +II +I+ LL Sbjct: 181 SRGYVFQMEMIVLASSLGYKIGEVGI-TFVDRFYGESKLGGTEIIQYIMGLL 231 >pir||G70463 dolichol-phosphate mannosyltransferase - Aquifex aeolicus >gi|2984166|gb|AAC07699.1| (AE000762) dolichol-phosphate mannosyltransferase [Aquifex aeolicus] Length = 322 Score = 97.9 bits (240), Expect = 8e-20 Identities = 72/199 (36%), Positives = 112/199 (56%), Gaps = 24/199 (12%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFG-----VR 51 +SV+IPAYNEE+ I + ++ + ++ E+I VDDGS D T ++ K V+ Sbjct: 2 ISVVIPAYNEEENIPVLYEKLKKVLDSLGEDYEIIFVDDGSTDRTPEILKEIANKDKKVK 61 Query: 52 VIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV 111 VIR N G+ AA+ G +HAKGD+I+ MDAD Q+DP++IPK++ + +G D V G R Sbjct: 62 VIRFRRNYGQTAAIYAGFEHAKGDVIITMDADLQNDPEDIPKLLEKMKEG-YDIVSGWR- 119 Query: 112 IKAGKRP-LVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEV- 169 K K P L RKL + I +I ++ D +A K + ++ Y + ++ Sbjct: 120 -KDRKDPFLSRKLPSKIANWIISKVTGVELHDYGCTLKAYKADI-----AKMYRLYGDMH 173 Query: 170 --LIKVAKK-GARIVEVPV 185 L +AK+ GA+I E+PV Sbjct: 174 RFLPALAKRFGAKITEIPV 192 >emb|CAA18811.1| (AL023093) putative transferase [Mycobacterium leprae] Length = 239 Score = 97.9 bits (240), Expect = 8e-20 Identities = 62/202 (30%), Positives = 107/202 (52%), Gaps = 16/202 (7%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGKG 62 V ++IPA+NE IG+V+ ++ + V+ VDDGS D T ++A R G ++R P N G+G Sbjct: 10 VWIVIPAFNEAAIIGEVVTDVRAVFDHVVCVDDGSADGTGEIALRAGAHLVRHPVNLGQG 69 Query: 63 AAMREGIKHAK----GDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV--IKAGK 116 AA++ G+++A+ + DADGQH K++ ++ + D D VIG R + G+ Sbjct: 70 AAIQTGVEYARRQPAAQVFATFDADGQHRVKDLAALVDRLGAHDVDVVIGTRFGRLDGGR 129 Query: 117 RPLVRKLSNFITTTLIR--AKIKQK-----VDDTQSGFRAIKREFLP--DIESERYEVET 167 P++ K F+ ++R A++ ++ + DT +G R ++ DI Sbjct: 130 LPIL-KGPPFLKRVVLRTAARLSRRGRRLGLTDTNNGLRVFNKKVADGLDITMTGMSHAN 188 Query: 168 EVLIKVAKKGARIVEVPVSTRY 189 E ++ +A R+ EVPV Y Sbjct: 189 EFVMLIADNHWRVDEVPVEVLY 210 >gb|AAB63812.1| (AF009829) unknown [Mycobacterium bovis] Length = 218 Score = 96.3 bits (236), Expect = 2e-19 Identities = 70/195 (35%), Positives = 106/195 (53%), Gaps = 9/195 (4%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGKG 62 V+V++P NEE+ + VLA IP +VVD+ S D+TA VA R G +V+ P G G Sbjct: 6 VTVVLPCLNEEESLPAVLAAIPAGYR-ALVVDNNSTDDTATVAARHGAQVVVEPRP-GYG 63 Query: 63 AAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKR-PLVR 121 +A+ G+ A I+ +DADG D ++PK++A + KG AD V G+R AG P V Sbjct: 64 SAVHAGVLAATTPIVAVIDADGSMDAGDLPKLVAELDKG-ADLVTGRRRPVAGLHWPWVA 122 Query: 122 KLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPD--IESERYEVETEVLIKVAKKGAR 179 ++ + + +R + + V D + R +RE L D + R E+L++ A G R Sbjct: 123 RVGTVVMSWRLRTRHRLPVHDI-APMRVARREALLDLGVVDRRSGYPLELLVRAAAAGWR 181 Query: 180 IVEVPVSTRYDVETG 194 +VE+ VS Y TG Sbjct: 182 VVELDVS--YGPRTG 194 >pir||T33929 hypothetical protein Y66H1A.2 - Caenorhabditis elegans >gi|4226150|gb|AAD12857.1| (AF125462) similar to glycosyl transferases (Pfam:PF00535, Score=80.8, E=2.9e-20, N=1); strong similarity to dolichol-phosphate-mannose synthase [Caenorhabditis elegans] Length = 244 Score = 95.6 bits (234), Expect = 4e-19 Identities = 70/207 (33%), Positives = 101/207 (47%), Gaps = 26/207 (12%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFV----NEVIVVDDGSKDNTADVAK----RFGVRVI 53 K S+I+P YNE++ + + I ++ +EVI+VDD S D T +AK +G I Sbjct: 11 KYSIILPTYNEKENLPICIWLIENYLKEVSHEVIIVDDASPDGTQGIAKLLQKEYGDDKI 70 Query: 54 RLPENRGK---GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 + GK G A G+ A+G+ I+ MDAD H PK IP++IA K D V G R Sbjct: 71 LIKPRVGKLGLGTAYSHGLSFARGEFIILMDADLSHHPKFIPEMIALQHKYKLDIVTGTR 130 Query: 111 VIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER- 162 G KR + K +NF+ L + V D FR KR+ L + +E Sbjct: 131 YKDGGGVSGWDLKRKTISKGANFLAQFL----LNPGVSDLTGSFRLYKRDILSKLIAESV 186 Query: 163 ---YEVETEVLIKVAKKGARIVEVPVS 186 Y + E++ + K G RI EVP+S Sbjct: 187 SKGYVFQMEMMFRAKKSGYRIGEVPIS 213 >gi|6753670 dolichol-phosphate (beta-D) mannosyltransferase 1 [Mus musculus] >gi|3073773|dbj|BAA25759.1| (AB004789) dolichol-phosphate-mannose synthase [Mus musculus] Length = 260 Score = 94.4 bits (231), Expect = 9e-19 Identities = 65/209 (31%), Positives = 105/209 (50%), Gaps = 28/209 (13%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNE------VIVVDDGSKDNTADVAKRFGV----- 50 K SV++P YNE + + ++ + + +E +I++DDGS D T +VA++ Sbjct: 26 KYSVLLPTYNERENLPLIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIYGPD 85 Query: 51 RVIRLPENR--GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 R++ P + G G A GIKHA G+ ++ MDAD H PK IP+ I +G+ D V G Sbjct: 86 RILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSG 145 Query: 109 KRVIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI--- 158 R G KR ++ + +NFIT L+R D FR ++E L + Sbjct: 146 TRYKGNGGVYGWDLKRKIISRGANFITQILLR----PGASDLTGSFRLYRKEVLQKLIEK 201 Query: 159 -ESERYEVETEVLIKVAKKGARIVEVPVS 186 S+ Y + E++++ + I EVP+S Sbjct: 202 CVSKGYVFQMEMIVRARQMNYTIGEVPIS 230 >gb|AAG32629.1|AF102883_1 (AF102883) mannose phospho-dolichol synthase [Hypocrea jecorina] Length = 243 Score = 94.0 bits (230), Expect = 1e-18 Identities = 70/209 (33%), Positives = 99/209 (46%), Gaps = 29/209 (13%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNE------VIVVDDGSKDNTADVA----KRFGVR 51 K SVI+P YNE K + V + E +I+VDDGS D T DVA K + Sbjct: 10 KYSVILPTYNERKNLPIVAWLLNRTFTEHQLDWELIIVDDGSPDGTQDVANQLVKAYAPH 69 Query: 52 VIRLPENRGK---GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 V+ L GK G A G++ G+ ++ MDAD H PK IP++IA KG+ D V G Sbjct: 70 VV-LKTRSGKLGLGTAYVHGLQFVTGNFVIIMDADFSHHPKFIPQMIAVQKKGNYDIVTG 128 Query: 109 KRVIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI--- 158 R G KR V + +N T++R V D FR K+ L + Sbjct: 129 TRYAGNGGVFGWDLKRKFVSRGANLFADTVLR----PGVSDLTGSFRLYKKSVLEKVISS 184 Query: 159 -ESERYEVETEVLIKVAKKGARIVEVPVS 186 ES+ Y + E++++ G + EVP+S Sbjct: 185 TESKGYTFQMEMMVRAKAMGCTVAEVPIS 213 >gi|4503363 dolichyl-phosphate mannosyltransferase polypeptide 1; dolichol monophosphate mannose synthase [Homo sapiens] >gi|11420524|ref|XP_009467.1| dolichyl-phosphate mannosyltransferase polypeptide 1 [Homo sapiens] >gi|3062806|dbj|BAA25646.1| (D86198) dolichol-phosphate-mannose synthase [Homo sapiens] >gi|5817251|emb|CAB53749.1| (AL034553) dJ914P20.1 (dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit) [Homo sapiens] Length = 260 Score = 93.6 bits (229), Expect = 2e-18 Identities = 65/209 (31%), Positives = 105/209 (50%), Gaps = 28/209 (13%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNE------VIVVDDGSKDNTADVAKRF-----GV 50 K SV++P YNE + + ++ + + +E +I++DDGS D T DVA++ Sbjct: 26 KYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSD 85 Query: 51 RVIRLPENR--GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 R++ P + G G A G+KHA G+ I+ MDAD H PK IP+ I +G+ D V G Sbjct: 86 RILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSG 145 Query: 109 KRVIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI--- 158 R G KR ++ + +NF+T L+R D FR ++E L + Sbjct: 146 TRYKGNGGVYGWDLKRKIISRGANFLTQILLR----PGASDLTGSFRLYRKEVLEKLIEK 201 Query: 159 -ESERYEVETEVLIKVAKKGARIVEVPVS 186 S+ Y + E++++ + I EVP+S Sbjct: 202 CVSKGYVFQMEMIVRARQLNYTIGEVPIS 230 >gi|6325029 UDP-glucose:dolichyl-phosphate glucosyltransferase; Alg5p [Saccharomyces cerevisiae] >gi|728823|sp|P40350|ALG5_YEAST DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE >gi|1077101|pir||S48136 dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) [validated] - yeast (Saccharomyces cerevisiae) >gi|535141|emb|CAA54680.1| (X77573) dolichyl-phosphate beta-glucosyltransferase [Saccharomyces cerevisiae] >gi|1181261|emb|CAA64260.1| (X94561) dolichyl-phosphate beta-glucosyltransferase [Saccharomyces cerevisiae] >gi|1370470|emb|CAA97942.1| (Z73583) ORF YPL227c [Saccharomyces cerevisiae] Length = 334 Score = 93.2 bits (228), Expect = 2e-18 Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 36/220 (16%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNE-------VIVVDDGSKDNTADVAKRF------- 48 +SV+IP+YNE RI +L + F+ E +++VDDGS DNT + Sbjct: 75 LSVVIPSYNETGRILLMLTDAISFLKEKYGSRWEIVIVDDGSTDNTTQYCLKICKEQFKL 134 Query: 49 ---GVRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIK---GD 102 R+I+ +NRGKG A+R+G H +G +F DADG ++ K+I I K Sbjct: 135 NYEQFRIIKFSQNRGKGGAVRQGFLHIRGKYGLFADADGASKFSDVEKLIDAISKIETSS 194 Query: 103 ADFVIGKRVIKAG------------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAI 150 D K + G KR ++R + TL+ + + DTQ GF+ Sbjct: 195 TDLKTTKPAVAIGSRAHMVNTEAVIKRSMIRNCLMYGFHTLVFIFGIRSIKDTQCGFKLF 254 Query: 151 KR----EFLPDIESERYEVETEVLIKVAKKGARIVEVPVS 186 R + P + +E + + E+LI +K +I E+P+S Sbjct: 255 NRAAILKIFPYLHTEGWIFDVEILILAIRKRIQIEEIPIS 294 >gb|AAD30975.1|AF121895_1 (AF121895) dolichol-phosphate-mannose synthase [Cricetulus griseus] Length = 266 Score = 93.2 bits (228), Expect = 2e-18 Identities = 65/209 (31%), Positives = 105/209 (50%), Gaps = 28/209 (13%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNE------VIVVDDGSKDNTADVAKRFGV----- 50 K SV++P YNE + + ++ + + +E +I++DDGS D T +VA++ Sbjct: 32 KYSVLLPTYNERENLPLIVWLLVKSFSESSINYEIIIIDDGSPDGTREVAEQLEKIYGPD 91 Query: 51 RVIRLPENR--GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 R++ P + G G A GIKHA G+ ++ MDAD H PK IP+ I +G+ D V G Sbjct: 92 RILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSG 151 Query: 109 KRVIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI--- 158 R G KR ++ + +NFIT L+R D FR ++E L + Sbjct: 152 TRYKGNGGVYGWDLKRKIISRGANFITQILLR----PGASDLTGSFRLYRKEVLQKLIEK 207 Query: 159 -ESERYEVETEVLIKVAKKGARIVEVPVS 186 S+ Y + E++++ + I EVP+S Sbjct: 208 CVSKGYVFQMEMIVRARQLNYTIGEVPIS 236 >pir||F70546 hypothetical protein Rv0539 - Mycobacterium tuberculosis (strain H37RV) >gi|2114001|emb|CAB08973.1| (Z95558) hypothetical protein Rv0539 [Mycobacterium tuberculosis] Length = 210 Score = 92.1 bits (225), Expect = 5e-18 Identities = 68/192 (35%), Positives = 103/192 (53%), Gaps = 9/192 (4%) Query: 6 IIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGKGAAM 65 ++P NEE+ + VLA IP +VVD+ S D+TA VA R G +V+ P G G+A+ Sbjct: 1 MLPCLNEEESLPAVLAAIPAGYR-ALVVDNNSTDDTATVAARHGAQVVVEPRP-GYGSAV 58 Query: 66 REGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKR-PLVRKLS 124 G+ A I+ +DADG D ++PK++A + KG AD V G+R AG P V ++ Sbjct: 59 HAGVLAATTPIVAVIDADGSMDAGDLPKLVAELDKG-ADLVTGRRRPVAGLHWPWVARVG 117 Query: 125 NFITTTLIRAKIKQKVDDTQSGFRAIKREFLPD--IESERYEVETEVLIKVAKKGARIVE 182 + + +R + + V D + R +RE L D + R E+L++ A G R+VE Sbjct: 118 TVVMSWRLRTRHRLPVHDI-APMRVARREALLDLGVVDRRSGYPLELLVRAAAAGWRVVE 176 Query: 183 VPVSTRYDVETG 194 + VS Y TG Sbjct: 177 LDVS--YGPRTG 186 >gb|AAK42146.1| Dolichyl-phosphate mannose synthase related protein [Sulfolobus solfataricus] Length = 242 Score = 90.5 bits (221), Expect = 1e-17 Identities = 62/163 (38%), Positives = 90/163 (55%), Gaps = 11/163 (6%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVN--EVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 +S+IIPA+NEE+RIG+ L +I + E++VV DG DNT +V K+F V+++ G Sbjct: 2 ISIIIPAFNEERRIGRTLEKISSTLPNAEIVVVFDGH-DNTPEVVKKFPVKLLISESRLG 60 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLV 120 KG A++ GI + ++ +DAD +E+ KI++ DAD VI KR I PL Sbjct: 61 KGGAIKRGINESNFQRVLLLDADFPITEEELDKILST----DADLVIPKRKIVG--MPLK 114 Query: 121 RKL--SNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESE 161 RK FI T I K D Q+G + + RE + DI E Sbjct: 115 RKFLHKGFIIITKILFPSLAKFSDFQAGVKLVNREKVLDILDE 157 >emb|CAB61668.1| (AL133213) putative glycosyl transferase. [Streptomyces coelicolor A3(2)] Length = 302 Score = 90.1 bits (220), Expect = 2e-17 Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 24/218 (11%) Query: 5 VIIPAYNEEKRIGKVLAEIPEFVNE--VIVVDDGSKDNTADVAKRFG-----VRVIRLPE 57 VIIP YNE + I ++ + E V E V+V DD S D T +A V+V+ Sbjct: 25 VIIPTYNEAENIKAIVTRVREAVPEAHVLVADDNSPDGTGKLADELAAADDHVQVMHRKG 84 Query: 58 NRGKGAA----MREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIK 113 G GAA R G++H G +++ MDADG H P+E+P+++ +KG AD V+G R + Sbjct: 85 KEGLGAAYLAGFRWGLEHGYG-VLIEMDADGSHQPEELPRLLT-ALKG-ADLVLGSRWVP 141 Query: 114 AGK---RPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREF-----LPDIESERYEV 165 G+ P R++ + + R + + D G+RA +RE L ++ S+ Y Sbjct: 142 GGRVVNWPKSREIISRGGSMYSRIALDLPLRDITGGYRAFRRETLEGLGLEEVASQGYCF 201 Query: 166 ETEVLIKVAKKGARIVEVPVSTRYDVETGHFRF-RDII 202 + ++ + K G +VEVP+ T + E G + RDI+ Sbjct: 202 QVDLARRAIKAGYHVVEVPI-TFVERELGDSKMSRDIL 238 >gb|AAK41593.1| Dolichyl-phosphate mannose synthase related protein [Sulfolobus solfataricus] Length = 228 Score = 89.7 bits (219), Expect = 2e-17 Identities = 67/196 (34%), Positives = 105/196 (53%), Gaps = 15/196 (7%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVN--EVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 +SVIIPA+NEE+RIGK L +I + EV+VV DG DNT +V K+F V++I E G Sbjct: 25 ISVIIPAFNEERRIGKTLEKISSTLPNAEVVVVFDGH-DNTPEVVKKFPVKLIISKERLG 83 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPLV 120 KG A++ GI + ++ +DAD +E+ KI++ DAD VI +R I PL Sbjct: 84 KGMALKRGITESNFQRVLLLDADFPITEEELNKILST----DADLVIPRRKIIG--MPLK 137 Query: 121 RKLSN--FITTTLIRAKIKQKVDDTQSGFRAIKRE----FLPDIESERYEVETEVLIKVA 174 R+ + FI T I K D Q+G + + RE L ++ + + ++ Sbjct: 138 RRFLHKAFIVLTKILFPSLLKFSDFQAGVKLVNREKVVSVLDELIINDFLFDVNLIYAFK 197 Query: 175 KKGARIVEVPVSTRYD 190 ++ +I EV ++ +D Sbjct: 198 RRHYKIKEVEINYIHD 213 >pir||T40534 dolichyl-phosphate beta-gluco syltransferase - fission yeast (Schizosaccharomyces pombe) >gi|3116140|emb|CAA18889.1| (AL023288) dolichyl-phosphate beta-glucosyltransferase [Schizosaccharomyces pombe] Length = 322 Score = 89.3 bits (218), Expect = 3e-17 Identities = 64/218 (29%), Positives = 100/218 (45%), Gaps = 32/218 (14%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN--------------EVIVVDDGSKDNTADVAK 46 ++++VI+PAYNE KRIG +L E + + E+++VDD SKD T + Sbjct: 62 IQITVIVPAYNESKRIGNMLQETVDHLEKYYRSSSSAGQRRWEILIVDDESKDTTVNAVL 121 Query: 47 RFG--------VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPI 98 F +RV L NRGKG A+ G+ +A+G +F DADG ++ + + Sbjct: 122 EFSNKLDLRDHLRVCSLKRNRGKGGAVTWGMLYARGQYAIFADADGASQFSDLELLFKNM 181 Query: 99 IKGD-ADFVIGKRVIKAG-----KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKR 152 G V+G R KR +R L++ +++ DTQ GF+ R Sbjct: 182 PPGPRGGVVVGSRAHMVNTAAVVKRSFIRNFLMHCFHKLLQILGIREIGDTQCGFKLFSR 241 Query: 153 E----FLPDIESERYEVETEVLIKVAKKGARIVEVPVS 186 E P + E + + EVL G I+EVP++ Sbjct: 242 EAYQSIFPRMHVEGWIFDIEVLTLARFFGLPIIEVPIT 279 >pir||T38633 dolichol monophosphate mannose synthase - fission yeast (Schizosaccharomyces pombe) >gi|2258414|gb|AAC98795.1| (AF007873) dolichol monophosphate mannose synthase [Schizosaccharomyces pombe] >gi|2388967|emb|CAB11700.1| (Z98979) dolichol-phosphate mannosyltransferase [Schizosaccharomyces pombe] Length = 236 Score = 88.5 bits (216), Expect = 5e-17 Identities = 62/209 (29%), Positives = 100/209 (47%), Gaps = 28/209 (13%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKR----FGVR 51 K SV++P YNE K + + I + + E++++DD S D T +VAK +G Sbjct: 3 KYSVLLPTYNERKNLPIITYLIAKTFDQEKLDWEIVIIDDASPDGTQEVAKELQKIYGED 62 Query: 52 VIRLPENRGK---GAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 I L GK G A G+K A GD ++ MDAD H PK +P+ I + + D V+G Sbjct: 63 KILLKPRSGKLGLGTAYIHGLKFATGDFVIIMDADFSHHPKYLPEFIKLQKEHNYDIVLG 122 Query: 109 KRVIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFL----PD 157 R K G KR + + +N + +T++ V D FR K+ L + Sbjct: 123 TRYAKDGGVYGWNLKRKFISRGANLLASTVLGT----GVSDVTGSFRLYKKPVLETLMSE 178 Query: 158 IESERYEVETEVLIKVAKKGARIVEVPVS 186 + S+ Y + E++ + + I EVP++ Sbjct: 179 VTSKGYVFQMEIIARAREHNYTIGEVPIA 207 >gb|AAC98797.1| (AF007875) dolichol monophosphate mannose synthase [Homo sapiens] Length = 253 Score = 88.5 bits (216), Expect = 5e-17 Identities = 63/209 (30%), Positives = 102/209 (48%), Gaps = 28/209 (13%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNE------VIVVDDGSKDNTADVAKRF-----GV 50 K SV++P YNE + + ++ + + +E +I++DDGS D T DVA++ Sbjct: 19 KYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSD 78 Query: 51 RVIRLPENR--GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 R++ P + G G A G+KHA G+ I+ MDAD H PK IP+ I +G+ D G Sbjct: 79 RILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKKKEGNFDIASG 138 Query: 109 KRVIKAG-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI--- 158 R G KR ++ + +NF+T L + D FR +E L + Sbjct: 139 TRYKGNGGIYGWDLKRKIISRGANFLTQIL----LTPGASDLTGSFRLYPKEVLEKLIEK 194 Query: 159 -ESERYEVETEVLIKVAKKGARIVEVPVS 186 S+ Y + E++++ + I EVP+S Sbjct: 195 CVSKGYVFQMEMIVRARQLNYTIGEVPIS 223 >gb|AAK43334.1| Dolichol-phosphate mannosyltransferase [Sulfolobus solfataricus] Length = 255 Score = 87.8 bits (214), Expect = 9e-17 Identities = 66/228 (28%), Positives = 115/228 (49%), Gaps = 25/228 (10%) Query: 4 SVIIPAYNEEKRIGKVLAEIPEFV---NEVIVVDDGSKDNTADVAKRFGVR---VIRLPE 57 S++IP YNE I K++ EI V + +++VDD S D TA + + + V+ Sbjct: 27 SIVIPTYNERDNIVKLVEEINRIVPYNSRILIVDDNSPDGTALILQELNIHNLTVLIRHN 86 Query: 58 NRGKGAAMREGIKHA---KGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKA 114 RG G+A+R GI A + D IV MDAD H+PK +P+++ + + D VIG R + Sbjct: 87 ERGLGSALRYGISKAIELESDFIVTMDADFSHNPKYLPEMMKIALNENCDLVIGSRYVIG 146 Query: 115 G-------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER---YE 164 G R ++ K +N++ + + I +D+T + +R L +E + YE Sbjct: 147 GGIENWSLSRRIISKGANYLFKLVSHSPI---MDNTSNYRIYSRRAALLALECDTTNGYE 203 Query: 165 VETEVLIKVAKKGARIVEVPVSTRYDVETG--HFRFRDIINFILTLLR 210 + + K+ + +I E P+ D +TG ++I+N+ L ++R Sbjct: 204 FQICSIFKIIRNNLKIKEYPI-IFVDRKTGKSKLNLKEILNWFLYIIR 250 >pir||B75100 glycosyltransferase PAB1587 - Pyrococcus abyssi (strain Orsay) >gi|5458615|emb|CAB50103.1| (AJ248286) glycosyltransferase [Pyrococcus abyssi] Length = 233 Score = 87.4 bits (213), Expect = 1e-16 Identities = 65/205 (31%), Positives = 105/205 (50%), Gaps = 25/205 (12%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIP-------EFVNEVIVVDDGSKDNTADVAKRFGVRVIR 54 +V V++PAYNEE+ IGKV+ EIP + V+V + S D T ++A+ G V Sbjct: 3 RVVVLLPAYNEEETIGKVIDEIPVKKLEKEGYKVTVVVANGPSTDRTEEIARNKGAIVY- 61 Query: 55 LPENRGKGAAMREGIKHAKG------DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 N KG R+ +KHA D +V +DAD + P+ I I+ + + D VIG Sbjct: 62 ---NIAKGGKARD-VKHALSMIDFPYDYLVMLDADYTYPPQYIYDIVKAL--EEYDVVIG 115 Query: 109 KRV---IKAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIE--SERY 163 R+ I+ G P V KL N+ + + +K+ D +G ++ L IE + + Sbjct: 116 SRLKGKIEDGAMPKVNKLGNWGLSLIATILYGKKISDVCTGMWGFRKYVLDSIEIDANGF 175 Query: 164 EVETEVLIKVAKKGARIVEVPVSTR 188 ++E + ++ KKG +I EVP++ R Sbjct: 176 DLEANLYVEAVKKGFKIGEVPINYR 200 >gb|AAG19457.1| (AE005038) glycosyl transferase-like; Gtl [Halobacterium sp. NRC-1] Length = 305 Score = 87.4 bits (213), Expect = 1e-16 Identities = 60/215 (27%), Positives = 103/215 (47%), Gaps = 9/215 (4%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEF-VNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 +V ++P NE I V+ + E V V+VVD S D+TA VA G V++ G Sbjct: 7 EVCALVPTRNEAATIADVIDGLFEVGVGHVLVVDGNSADDTAAVAAEHGAEVVQ-QSGDG 65 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV--IKAGKRP 118 KG A+REG+ + ++ +D DG + P + +++ P++ G+A+ V+G R ++ G Sbjct: 66 KGQAVREGVSLIEAAYVLLLDGDGTNPPAQASRLLDPLVAGEAEHVVGDRTADMRPGAMS 125 Query: 119 LVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPD--IESERYEVETEVLIKVAKK 176 + ++ N + + D SG+RA E + +E + +ETE+ ++ ++ Sbjct: 126 TLNQIGNRLINRAFHRIHGEDYGDILSGYRAFTAESFDRMFLSAEGFGIETEMAVECSRH 185 Query: 177 GARIVEVPVSTRY---DVETGHFRFRDIINFILTL 208 VP + R D ET D ILTL Sbjct: 186 NITTRVVPTTYRARPDDSETNLHPISDGARIILTL 220 >emb|CAC11300.1| (AL445063) conserved hypothetical protein [Thermoplasma acidophilum] Length = 225 Score = 87.4 bits (213), Expect = 1e-16 Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 11/210 (5%) Query: 2 KVSVIIPAYNEEKRIGKVLAEI-PEFVN-EVIVVDDGSKDNTADVAKRFGVRVIRLPENR 59 KVS +IP NEE IG V+ I EF N E+IVVD S D T ++A+ G RVI P R Sbjct: 7 KVSFVIPTINEEGTIGSVIDGIRSEFPNSEIIVVDTNSTDRTREIARSKGARVIEEPR-R 65 Query: 60 GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV-IKAGKR- 117 G G A + GI A G+IIV MD DG + + +I +I DF+ R+ + K Sbjct: 66 GYGRAYQTGIPAASGEIIVCMDGDGTYPTDVVKPLIELLIADRVDFISCDRITFRTSKNY 125 Query: 118 PLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEVLIKV-AKK 176 + + N + IR K ++ D+QSG + E +++ + IK+ A + Sbjct: 126 TTLHYVGNMVLNLTIRILFKVRMVDSQSGMWVFRSEIYRKMKNLGNGMSFSQNIKIEAVR 185 Query: 177 GARIVEVPVS-----TRYDVETGHFRFRDI 201 +E+P+ T+ ++T H F ++ Sbjct: 186 HGVFMEIPIRYGVRITKPKLKTWHDGFHNL 215 >pir||E69142 mannosyltransferase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621387|gb|AAB84837.1| (AE000818) mannosyltransferase [Methanobacterium thermoautotrophicum] Length = 221 Score = 85.8 bits (209), Expect = 4e-16 Identities = 63/197 (31%), Positives = 105/197 (52%), Gaps = 14/197 (7%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFV--NEVIVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 ++ +IPAYNEEK IG ++ I +E+IVVD+ S D T+++A GVRVI +G Sbjct: 1 MTFLIPAYNEEKSIGPLIDRIKMLCPDSEIIVVDNNSSDRTSEIATSRGVRVI-FEGKQG 59 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGD-ADFVIGKRVI---KAGK 116 K AM ++ + + V MDAD + P + +++ ++K + AD V+G R+ + G Sbjct: 60 KANAMVAAFRNTRTEYAVMMDADLTYLPDD-SRVLVEVLKAEGADVVLGSRLNGEKEDGA 118 Query: 117 RPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER-----YEVETEVLI 171 + + N I + + + V D +G A R + I E +E+E E+ Sbjct: 119 ISRINTVGNHILS-FTASILYSPVSDVCTGHWAFNRRAIRHILEEGLNYSGFELEAEMFS 177 Query: 172 KVAKKGARIVEVPVSTR 188 K+A+ G +IVEVP++ R Sbjct: 178 KLARAGLKIVEVPITYR 194 >gb|AAF52633.1| (AE003620) CG7870 gene product [Drosophila melanogaster] Length = 326 Score = 85.8 bits (209), Expect = 4e-16 Identities = 71/202 (35%), Positives = 98/202 (48%), Gaps = 33/202 (16%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEI-----------PEFVNEVIVVDDGSKDNTADVA---- 45 +++SVI+PAYNEE+R+ +L E P F EVIVV DGS+D T VA Sbjct: 66 LELSVIVPAYNEEQRLPSMLDECLAFLEQKSAGTPNFTYEVIVVSDGSQDATVSVALGYS 125 Query: 46 KRFG---VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADG-----QHDPKEIP-KIIA 96 K+ G VRV+ L ENRGKG A+R G+ A+G ++F DADG +D E+ K +A Sbjct: 126 KKHGAEKVRVLELIENRGKGGAVRMGMLSARGRNLLFADADGATKFPDYDKLEVALKQLA 185 Query: 97 PIIKGDADFVIGKRVIKAGKRPLVRKLSNFITT----TLIRAKIKQKVDDTQSGF----R 148 P + D IG R R I L+ + + DTQ GF R Sbjct: 186 PEWRDDG-IAIGSRAHLENDAIATRSFFRTILMHGFHFLVWLFAVRSIRDTQCGFKLFTR 244 Query: 149 AIKREFLPDIESERYEVETEVL 170 R+ + ER+ + E+L Sbjct: 245 TTARKLFTSLHVERWAFDVELL 266 >pir||A71157 hypothetical protein PH0456 - Pyrococcus horikoshii >gi|3256859|dbj|BAA29542.1| (AP000002) 314aa long hypothetical protein [Pyrococcus horikoshii] Length = 314 Score = 85.0 bits (207), Expect = 6e-16 Identities = 65/197 (32%), Positives = 100/197 (49%), Gaps = 13/197 (6%) Query: 3 VSVIIPAYNEEKRIGKVLA-----EIPEFVNEVIVVDDGSKDNTADVAKRFG---VRVIR 54 +S+IIPAYNEE+ I + + + P V+EVIVVDDGS+D T + AK ++V++ Sbjct: 1 MSIIIPAYNEEENIKRAIKAALSQDYP--VSEVIVVDDGSEDGTYERAKEIKDHRLKVLK 58 Query: 55 LPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK-RVIK 113 + ++RGK A+ EG+K AKG +IV DAD + +++ D V G+ RVI Sbjct: 59 I-DHRGKAGAINEGLKIAKGSVIVTTDADSFMSKDAVRRLVERFYSDDVVAVGGQIRVIV 117 Query: 114 AGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIES-ERYEVETEVLIK 172 LV+ + + R K + + A +R+ L I +R VE K Sbjct: 118 ESFMTLVQDIEHLRIAMYRRGKELENLSLAPGPLSAFRRDVLEKIGGIQRSIVEDYATTK 177 Query: 173 VAKKGARIVEVPVSTRY 189 + KK R+V P + Y Sbjct: 178 IVKKYGRVVYAPKAKLY 194 >pir||T34006 hypothetical protein H43I07.2 - Caenorhabditis elegans >gi|4262643|gb|AAD14758.1| (AF125965) similar to glycosyl transferases (Pfam:PF00535, Score:55.6, E= 1.1e-12, N=1) [Caenorhabditis elegans] Length = 697 Score = 85.0 bits (207), Expect = 6e-16 Identities = 65/216 (30%), Positives = 104/216 (48%), Gaps = 33/216 (15%) Query: 3 VSVIIPAYNEEKRIGKVLAEI-----------PEFVNEVIVVDDGSKDNTADV-----AK 46 +SVIIPA NE +RI +L + +F E+IVVDDGS D TAD+ A+ Sbjct: 83 LSVIIPAMNEVERIEIMLDDCCDYLEARAEKDKDFTYEIIVVDDGSTDETADIVVQIGAR 142 Query: 47 RFGVRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADG-------QHDPKEIPKIIA--P 97 R +RV+++ NRGKG A++ G+ H+ G +I+F DADG ++ KE+ + P Sbjct: 143 RQNLRVLKMKANRGKGGAVKMGVLHSSGKLILFADADGATKFADFENLEKEMLRTAGGEP 202 Query: 98 IIKGDADFVIGKRVIKAGKRPLVRKLSNFITT----TLIRAKIKQKVDDTQSGF----RA 149 + + ++ R + VR + I L+ + + DTQ GF R+ Sbjct: 203 LDESFPAVIVASRAHLEAESMAVRSVPRTILMLGFHLLVYTFAARTIKDTQCGFKLFTRS 262 Query: 150 IKREFLPDIESERYEVETEVLIKVAKKGARIVEVPV 185 I P + ER+ + E++ + + EV V Sbjct: 263 IAARIFPVLHIERWAFDVELIFLCERWTVPVKEVSV 298 >gb|AAF79605.1|AC027665_6 (AC027665) F5M15.10 [Arabidopsis thaliana] Length = 256 Score = 85.0 bits (207), Expect = 6e-16 Identities = 60/184 (32%), Positives = 90/184 (48%), Gaps = 26/184 (14%) Query: 29 EVIVVDDGSKDNTADVAKR----FGVRVIRL---PENRGKGAAMREGIKHAKGDIIVFMD 81 E+IVVDDGS D T ++ K+ +G I L + G G A G+KHA GD +V MD Sbjct: 43 EIIVVDDGSPDGTQEIVKQLQQLYGEDRILLRARAKKLGLGTAYIHGLKHATGDFVVIMD 102 Query: 82 ADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAG---KRPLVRKLSNFITTTLIRAKIKQ 138 AD H PK +P I ++ +A V G R +K G L+RKL++ L + + Sbjct: 103 ADLSHHPKYLPSFIKKQLETNASIVTGTRYVKGGGVHGWNLMRKLTSRGANVLAQTLLWP 162 Query: 139 KVDDTQSGFRAI------------KREFLPDI----ESERYEVETEVLIKVAKKGARIVE 182 V D FR + K+ L D+ S+ Y + E++++ +KG I E Sbjct: 163 GVSDLTGSFRIMSDLRTSLFGRLYKKSALEDVISSCVSKGYVFQMEMIVRATRKGYHIEE 222 Query: 183 VPVS 186 VP++ Sbjct: 223 VPIT 226 >dbj|BAA19644.1| (AB002668) unnamed protein product [Actinobacillus actinomycetemcomitans] Length = 234 Score = 84.3 bits (205), Expect = 1e-15 Identities = 62/196 (31%), Positives = 97/196 (48%), Gaps = 9/196 (4%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN-EVIVVDDGSKDNTADVAKRFGVRVIRLPENR 59 MK+ +IIP YNE + I +L E+ ++ + IV++D KDNT+ + + +G VI LP N Sbjct: 1 MKILLIIPCYNESESIISLLDELKDYPEYDYIVINDCFKDNTSKIVRNYGANVIDLPINL 60 Query: 60 GKGAAMREGIKHAKG---DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAG- 115 G ++ G+ +A DI + +D DGQH P EI K++ IK D I R +++ Sbjct: 61 GLSGGVQTGMMYATKNDYDICIQIDGDGQHMPSEIYKLVDK-IKDGVDIAISSRFLESKD 119 Query: 116 --KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAI-KREFLPDIESERYEVETEVLIK 172 + +R L I+ + D SG RA K F + E + ++ Sbjct: 120 SYSQTFLRALGAKHIQFCIKLFSGLTLTDPTSGMRAFTKNVFQQMAYATNERPEPDTMLY 179 Query: 173 VAKKGARIVEVPVSTR 188 A+ G RI EV V+ R Sbjct: 180 FARLGYRIEEVQVTMR 195 >pir||T34632 probable bi-functional transferase/deacetylase - Streptomyces coelicolor >gi|5042285|emb|CAB44539.1| (AL078618) putative bi-functional transferase/deacetylase [Streptomyces coelicolor] Length = 743 Score = 83.5 bits (203), Expect = 2e-15 Identities = 50/120 (41%), Positives = 68/120 (56%), Gaps = 8/120 (6%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVN--EVIVVDDGSKDNTADVAKRFG---VRVIRLPE 57 VSVI+PAYNE++ I L + + E+IVVDDGS D TAD+A+ G VRV+R Sbjct: 389 VSVIVPAYNEKECIEATLRSLARSTHPVEIIVVDDGSTDGTADIAESLGLPGVRVVR-QA 447 Query: 58 NRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKR 117 N GK AA+ G++HA+ DI+V MD D +P + ++ P V G K G R Sbjct: 448 NAGKPAALNNGVRHARYDIVVMMDGDTVFEPDTVRHLVQPFADPSVGAVAGN--AKVGNR 505 >gi|7019323 dolichyl phosphate glucosyltransferase; Alg5, S. cerevisiae, homolog of [Homo sapiens] >gi|11359864|pir||T51776 dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) [imported] - human >gi|5281121|gb|AAD41465.1|AF102850_1 (AF102850) dolichyl-phosphate beta-glucosyltransferase [Homo sapiens] >gi|6841520|gb|AAF29113.1|AF161498_1 (AF161498) HSPC149 [Homo sapiens] Length = 324 Score = 83.5 bits (203), Expect = 2e-15 Identities = 67/202 (33%), Positives = 101/202 (49%), Gaps = 35/202 (17%) Query: 2 KVSVIIPAYNEEKRIGKVLAEI-----------PEFVNEVIVVDDGSKDNTADVA----K 46 ++SV++P+YNEEKR+ ++ E P F EVIVVDDGSKD T+ VA + Sbjct: 66 QLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQ 125 Query: 47 RFG---VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDA 103 ++G VRVI L +NRGKG A+R GI ++G+ I+ DADG ++ K+ + D Sbjct: 126 KYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL--NDL 183 Query: 104 DFVIGKRVIKAGKRPLVRKLS----NFITTTLIRA-------KIKQKVDDTQSGFRAIKR 152 + I G R + K S ++ T L+ + + DTQ GF+ R Sbjct: 184 QPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTR 243 Query: 153 E----FLPDIESERYEVETEVL 170 E + ER+ + E+L Sbjct: 244 EAASRTFSSLHVERWAFDVELL 265 >gb|AAG09682.1|AF183413_1 (AF183413) dolichyl-phosphate beta-glucosyltransferase [Homo sapiens] Length = 324 Score = 83.5 bits (203), Expect = 2e-15 Identities = 67/202 (33%), Positives = 101/202 (49%), Gaps = 35/202 (17%) Query: 2 KVSVIIPAYNEEKRIGKVLAEI-----------PEFVNEVIVVDDGSKDNTADVA----K 46 ++SV++P+YNEEKR+ ++ E P F EVIVVDDGSKD T+ VA + Sbjct: 66 QLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQ 125 Query: 47 RFG---VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDA 103 ++G VRVI L +NRGKG A+R GI ++G+ I+ DADG ++ K+ + D Sbjct: 126 KYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL--NDL 183 Query: 104 DFVIGKRVIKAGKRPLVRKLS----NFITTTLIRA-------KIKQKVDDTQSGFRAIKR 152 + I G R + K S ++ T L+ + + DTQ GF+ R Sbjct: 184 QPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTR 243 Query: 153 E----FLPDIESERYEVETEVL 170 E + ER+ + E+L Sbjct: 244 EAASRTFSSLHVERWAFDVELL 265 >pir||G75005 hyaluronan synthase related PAB1314 - Pyrococcus abyssi (strain Orsay) >gi|5458999|emb|CAB50485.1| (AJ248288) HYALURONAN SYNTHASE RELATED [Pyrococcus abyssi] Length = 350 Score = 82.3 bits (200), Expect = 4e-15 Identities = 69/193 (35%), Positives = 96/193 (48%), Gaps = 13/193 (6%) Query: 2 KVSVIIPAYNEEKRIGKVLA-----EIPEFVNEVIVVDDGSKDNTADVAKRFG---VRVI 53 KVSVIIPAYNEE+ I K + + P V EVIVVDDGS+D T + AK V+VI Sbjct: 37 KVSVIIPAYNEEENIKKAIKAALSQDYP--VEEVIVVDDGSEDGTYEKAKEVKDERVKVI 94 Query: 54 RLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK-RVI 112 R+ E++GK A+ EG+K AKG++IV DAD + +++ D V G+ RVI Sbjct: 95 RI-EHKGKAGAINEGLKLAKGEVIVVTDADSFMSRDAVRRLVERFHSEDVVAVGGQIRVI 153 Query: 113 KAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIES-ERYEVETEVLI 171 ++ + + RAK + + A +RE L I VE Sbjct: 154 VDSFLAFIQDIEHLRIAMYRRAKELEDLTLAPGPLSAFRREALERIGGFVNSLVEDYATT 213 Query: 172 KVAKKGARIVEVP 184 K KK ++V P Sbjct: 214 KALKKFGKVVYSP 226 >gb|AAC04771.1| (AF036677) PmrF [Salmonella typhimurium] Length = 327 Score = 81.9 bits (199), Expect = 5e-15 Identities = 62/221 (28%), Positives = 106/221 (47%), Gaps = 17/221 (7%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFGVRV--- 52 KVSV+IP YNE++ + +++ E++++DDGS D++A++ + Sbjct: 9 KVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVKASQEADSH 68 Query: 53 ---IRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 I L N G+ AA+ G H GD+I+ +DAD Q+ P+EIP+++A K D F + Sbjct: 69 IISILLNRNYGQHAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVA---KADEGFDVVG 125 Query: 110 RVIKAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEV 169 V + + L RK ++ I LI+ + + D RA +R + D +E T + Sbjct: 126 TVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYGCMLRAYRRPII-DTMLRCHERSTFI 184 Query: 170 LIKVAKKGARIVEVPV-STRYDVETGHFRFRDIINFILTLL 209 I R E+PV + + F +IN + L+ Sbjct: 185 PILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLV 225 >emb|CAB76989.1| (AL159178) putative glycosyltransferase [Streptomyces coelicolor A3(2)] Length = 242 Score = 81.5 bits (198), Expect = 7e-15 Identities = 58/183 (31%), Positives = 90/183 (48%), Gaps = 6/183 (3%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGKG 62 V V++P NE + VLA IP +VVD+GS D +AD+A+ G V+ P RG G Sbjct: 12 VDVVLPCLNEAGALPWVLARIPAGWR-ALVVDNGSTDGSADLARSLGATVVTEPR-RGFG 69 Query: 63 AAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKA-GKRPLVR 121 AA G+ A D++ F D D DP + + I G +D V+G+R +A G P+ Sbjct: 70 AACHAGLTAATADVVCFCDCDASLDPGLLTPFVREIRAGTSDLVLGRRRPQARGAWPVHA 129 Query: 122 KLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFL--PDIESERYEVETEVLIKVAKKGAR 179 + N ++R + ++ D RA +RE L + R +++++ A G R Sbjct: 130 RAGNLALARMLRRRTGLRLHDL-GPLRAARRERLLALGLTDRRSGYPLQMVVRAADAGWR 188 Query: 180 IVE 182 I E Sbjct: 189 IAE 191 >gb|AAG18896.1| (AE004992) dolichol-P-glucose synthetase; Dpg [Halobacterium sp. NRC-1] Length = 614 Score = 81.5 bits (198), Expect = 7e-15 Identities = 56/204 (27%), Positives = 96/204 (46%), Gaps = 19/204 (9%) Query: 1 MKVSVIIPAYNEEKRIGKVLAE--------IPEFVNEVIVVDDGSKDNT-----ADVAKR 47 ++VSV++PAYNE I + +P EVIV +DG D+T A A++ Sbjct: 6 VEVSVVLPAYNEADTIDATVHTTVETLAGFLPAGSFEVIVAEDGCDDDTPARADALAAEQ 65 Query: 48 FGVRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVI 107 VR + + G+G A+ A GD +V+ D D D + + ++ + G AD Sbjct: 66 SAVRHLHSEQRLGRGGALNAAFDVADGDTLVYFDTDLATDMRHLETLVERVRTGSADVAT 125 Query: 108 GKRVI--KAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKRE----FLPDIESE 161 G R + + RP R + + + +R + V D Q GF+A+ R + D+ E Sbjct: 126 GSRWMPGETADRPAKRGIPSRVFNGAVRTLLGSSVRDHQCGFKALSRSAFEALVDDVADE 185 Query: 162 RYEVETEVLIKVAKKGARIVEVPV 185 + +TE+L++ ++G + E V Sbjct: 186 HWFWDTELLVRAQRQGFDVEEFAV 209 >pir||B75440 rfbJ protein/conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6458811|gb|AAF10652.1|AE001958_6 (AE001958) rfbJ protein/conserved hypothetical protein [Deinococcus radiodurans] Length = 219 Score = 81.1 bits (197), Expect = 9e-15 Identities = 41/107 (38%), Positives = 63/107 (58%), Gaps = 1/107 (0%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGVRVIRLPENRGKG 62 V+V+IPA+NEE+ +G V+ EV+V DGS D TA VA+ G RV+ L EN GKG Sbjct: 12 VAVVIPAFNEEETVGDVVRAALTLTPEVVVASDGSADATAQVARTAGARVVELLENAGKG 71 Query: 63 AAMREGIKHAKGDIIVFMDADGQHDPKE-IPKIIAPIIKGDADFVIG 108 A+ ++ + +V +D D Q +E + ++ P++ G+ D IG Sbjct: 72 PALAAALQATDAEYVVMLDGDLQGLTREHLDVLLRPVLDGELDMTIG 118 >sp|P77757|YFBF_ECOLI HYPOTHETICAL 36.3 KD PROTEIN IN AIS-PMRD INTERGENIC REGION >gi|7446787|pir||D64996 hypothetical protein b2254 - Escherichia coli (strain K-12) >gi|1788588|gb|AAC75314.1| (AE000315) putative sugar transferase [Escherichia coli K12] >gi|1799606|dbj|BAA16077.1| (D90856) DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (EC 2.4.1.83) (DOLICHOL- PHOSPHATE MANNOSE SYNTHASE) (DOLICHYL-PHOSPHATE BETA-D- MANNOSYLTRANSFERASE). [Escherichia coli] Length = 322 Score = 79.6 bits (193), Expect = 3e-14 Identities = 60/221 (27%), Positives = 107/221 (48%), Gaps = 17/221 (7%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADV------AKRFG 49 KVSV+IP YNE++ + +++ E++++DDGS DN+A + A+ Sbjct: 9 KVSVVIPVYNEQESLPELIRRTTTACESLGKEYEILLIDDGSSDNSAHMLVEASQAENSH 68 Query: 50 VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 + I L N G+ +A+ G H GD+I+ +DAD Q+ P+EIP+++A K D + + Sbjct: 69 IVSILLNRNYGQHSAIMAGFSHVTGDLIITLDADLQNPPEEIPRLVA---KADEGYDVVG 125 Query: 110 RVIKAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYEVETEV 169 V + + RK ++ + LI+ + + D RA +R + D +E T + Sbjct: 126 TVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYGCMLRAYRRHIV-DAMLHCHERSTFI 184 Query: 170 LIKVAKKGARIVEVPV-STRYDVETGHFRFRDIINFILTLL 209 I R +E+PV + + F +IN + L+ Sbjct: 185 PILANIFARRAIEIPVHHAEREFGESKYSFMRLINLMYDLV 225 >gb|AAC35924.1| (AF071085) putative glycosyl transferase [Enterococcus faecalis] Length = 241 Score = 79.6 bits (193), Expect = 3e-14 Identities = 65/210 (30%), Positives = 96/210 (44%), Gaps = 30/210 (14%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEV---------IVVDDGSKDNTADVAKRFGVR 51 MKV +IIPAYNEE+ I + +A I F EV +V++DGS D T + + + Sbjct: 1 MKVLLIIPAYNEEENILRTIASIETFKQEVTHFQHELDYVVINDGSTDGTKQILEVNQIN 60 Query: 52 VIRLPENRGKGAAMREGIKHA---KGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIG 108 I L N G G A++ G K+A + D+ D DG HD +P ++ P+ +G F G Sbjct: 61 AIHLVLNLGIGGAVQTGYKYALENEYDVAXQFDGDGXHDIXSLPILLEPLAEGXCXFSXG 120 Query: 109 KRVIKAG---------KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIE 159 R I +R +R LS F I ++G R + F Sbjct: 121 SRFIPGNXASFQSXKMRRXGIRLLS-FCXXXAXGXTIYXVTXGXRAGNRKVIAFF----- 174 Query: 160 SERYEV---ETEVLIKVAKKGARIVEVPVS 186 ++RY E E ++ + KK IVE PV+ Sbjct: 175 AKRYPTNYPEPESIVHLIKKRFVIVERPVN 204 >pir||T00571 dolichyl-phosphate beta-glucosyltransferase homolog F12L6.29 - Arabidopsis thaliana >gi|6598395|gb|AAF18606.1|AC003674_1 (AC003674) putative dolichyl-phosphate beta-glucosyltransferase [Arabidopsis thaliana] Length = 336 Score = 78.8 bits (191), Expect = 5e-14 Identities = 65/230 (28%), Positives = 107/230 (46%), Gaps = 47/230 (20%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVN-----------EVIVVDDGSKDNTADVAKRF--- 48 +S+I+PAYNEE R+ L E +++ EV++VDDGS D T VA F Sbjct: 68 LSLIVPAYNEELRLPAALEETMDYLQDRASRDKSFSFEVVIVDDGSVDGTKRVAFDFIRK 127 Query: 49 ----GVRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKI---------- 94 +RVI L +N+GKG A+R+G+ H++G +++ +DADG ++ K+ Sbjct: 128 YTIDNIRVIPLGKNQGKGEAIRKGMLHSRGQLLLMLDADGATKVTDLEKLENQINAVARE 187 Query: 95 ---IAPIIKGDADFVIGKRVIKA-GKRPLVRKLS--------NFITT---TLIRAKIKQK 139 I D DF IG + A G R + + + NF+ ++ Sbjct: 188 EYSIRNPASKDMDFKIGDVQVSAFGSRAHLEEKALATRKWYRNFLMKGFHLVVLLAAGPG 247 Query: 140 VDDTQSGF----RAIKREFLPDIESERYEVETEVLIKVAKKGARIVEVPV 185 + DTQ GF RA R ++ +R+ + E++ + +VE+ V Sbjct: 248 IRDTQCGFKMFTRAAARRLFTNVHLKRWCFDVELVYLCKRFNIPMVEISV 297 >gb|AAD01952.1| (AF033015) unknown [Listeria monocytogenes] Length = 315 Score = 78.8 bits (191), Expect = 5e-14 Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 14/221 (6%) Query: 2 KVSVIIPAYNEEKRIGKVLAEI-PEFVN-EVIVVDDGSKDNTADVAKRFGVRVIRLPENR 59 KV+V++P YNEE IGKV+ + E N ++ V D+ SKD T ++AK G ++R + Sbjct: 7 KVAVLLPCYNEELTIGKVIDDFKKELPNADIYVYDNNSKDKTFEIAKDHGA-IVRKEMRQ 65 Query: 60 GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV-----IKA 114 GKG +R D + +D D + + +I+ + +A+ VIG R+ + Sbjct: 66 GKGNVVRSMFADIDADYYLMVDGDDTYPAEYCHEILEVLRNKEANMVIGDRLSNGTYTEE 125 Query: 115 GKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLP--DIESERYEVETEVLIK 172 KR N + I K + D +G+R R F+ + S +E+ETE+ I Sbjct: 126 NKRNF-HDFGNSLVRNTINRIFKSNLRDIMTGYRGFDRYFVKTMPVLSPGFEIETEMSIH 184 Query: 173 VAKKGARIVEVPVSTRYDVETGHFR---FRDIINFILTLLR 210 + + E+ + R E + F D I+T++R Sbjct: 185 ALENRFLVKEIEIDYRDRPEGSESKLNTFSDGFKVIMTIVR 225 >pir||D72736 probable dolichol-phosphate-mannosyltransferase APE0426 - Aeropyrum pernix (strain K1) >gi|5104068|dbj|BAA79384.1| (AP000059) 373aa long hypothetical dolichol-phosphate-mannosyltransferase [Aeropyrum pernix] Length = 373 Score = 78.4 bits (190), Expect = 6e-14 Identities = 62/206 (30%), Positives = 101/206 (48%), Gaps = 21/206 (10%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN-------EVIVVDDGSKDNTADVAKRFG----- 49 +VSVI+P NE I + + + + E++ VDD S D T + +R Sbjct: 22 EVSVIVPTLNERDNIRPLYVGLKKSLEGAGLECFEIVFVDDSSTDGTIEEVERLSRSDPR 81 Query: 50 VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 VR+I +G A+ EG++ A+G + V MDAD QH P+ +P ++ + G+AD + Sbjct: 82 VRLIVRRGEKGLSRAVLEGLRRARGRVAVVMDADLQHPPETVPLLVEKVAGGEADLAVAS 141 Query: 110 RVIKAGK---RPLVRKLSNFITTTLIRAKI--KQKVDDTQSGFRAIKREFL-PDIESER- 162 R G+ LVR++ + L I ++ D SGF A+ E + P I S R Sbjct: 142 RYAPGGRVEGWSLVRRIISRGAVLLAWLLIPESRRTRDPVSGFFAVNLERVRPAIVSGRG 201 Query: 163 YEVETEVLIKVAKKGARIVEVPVSTR 188 +++ E+L AR+V+VP + R Sbjct: 202 FKILLEIL--YTNPYARVVDVPFTFR 225 >emb|CAC15463.1| (AJ294477) putative polyprenol phosphate mannosyl transferase 1 (Ppm1) [Mycobacterium smegmatis] Length = 265 Score = 77.6 bits (188), Expect = 1e-13 Identities = 60/201 (29%), Positives = 95/201 (46%), Gaps = 20/201 (9%) Query: 5 VIIPAYNEEKRIGKVLAEIPEFVNEV--IVVDDGSKDNTADVAKRFG------VRVIRLP 56 VIIP YNE + + ++ + +V +VVDDGS D T +A V V+ Sbjct: 26 VIIPTYNERENLPLIVGRVHHACPQVHILVVDDGSPDGTGALADELALADPDRVHVMHRT 85 Query: 57 ENRGKGAAMREGIKHA--KG-DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIK 113 G GAA G +G ++V MDADG H P+E+ +++ + G AD IG R + Sbjct: 86 SKAGLGAAYLAGFDWGLRRGYSVLVEMDADGSHAPEELSRLLDAVDAG-ADLAIGSRYVP 144 Query: 114 AG---KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDI-----ESERYEV 165 G P R + + T R + + D +G+RA +RE L I +S+ Y Sbjct: 145 GGTVRNWPWRRLVLSKTANTYSRFLLGVGIHDITAGYRAYRREVLEKIDLSAVDSKGYCF 204 Query: 166 ETEVLIKVAKKGARIVEVPVS 186 + ++ + G +VEVP++ Sbjct: 205 QIDLTWRAINNGFSVVEVPIT 225 >pir||T44819 dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) [imported] - Ajellomyces capsulata >gi|6014695|gb|AAF01464.1|AF189370_1 (AF189370) dolichyl-phosphate beta-glucosyltransferase [Ajellomyces capsulatus] Length = 406 Score = 76.1 bits (184), Expect = 3e-13 Identities = 67/282 (23%), Positives = 106/282 (36%), Gaps = 96/282 (34%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVN---------------------------------- 28 +SV++PA+NEE R+G +L E ++ Sbjct: 90 MSVVVPAFNEEDRLGGMLEEAVNYLERTYGKLAECQQDGTLLHEVTKCERTRRRKLDGGA 149 Query: 29 ---------------EVIVVDDGSKDNTADVAKRFG------------------------ 49 E++VV DGS D T + A F Sbjct: 150 NGSANRSADMPVRGWEILVVSDGSTDGTVETALAFAKDHQLSPHPKSHPGPWSTVADADG 209 Query: 50 -------VRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIK-- 100 +RVI L +NRGKG A+ G++H +G ++F DADG ++ K+++ + Sbjct: 210 VHTPPGTIRVITLTKNRGKGGAVTHGMRHVRGQYVIFADADGASRFDDLGKLVSACQRIE 269 Query: 101 --GDADFVIGKRVIKAGKRPLVR--KLSNFITTT------LIRAKIKQKVDDTQSGFRAI 150 +G R G +V+ KL NF+ + ++ + DTQ GF+ Sbjct: 270 DVQSRGLAVGSRAHLVGSEAVVKRSKLRNFLMHSFHLILRILTPPATASIKDTQCGFKLF 329 Query: 151 KREFLPDI----ESERYEVETEVLIKVAKKGARIVEVPVSTR 188 R LP I SE + + E+L+ G + EVPV R Sbjct: 330 SRASLPYIIPYMHSEGWIFDVEMLMLAEFAGIPVAEVPVGWR 371 >gi|6325441 dolichol phosphate mannose synthase; Dpm1p [Saccharomyces cerevisiae] >gi|118823|sp|P14020|DPM1_YEAST DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (DOLICHOL-PHOSPHATE MANNOSE SYNTHASE) (DOLICHYL-PHOSPHATE BETA-D-MANNOSYLTRANSFERASE) >gi|83002|pir||A32122 dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) precursor - yeast (Saccharomyces cerevisiae) >gi|171418|gb|AAA34578.1| (J04184) dolichol phosphate mannose synthase precursor (EC 2.4.1.83) [Saccharomyces cerevisiae] >gi|786315|gb|AAB68116.1| (U25842) Dolichol-phosphate mannosyltransferase (Dolichol-phosphate mannose synthase) (Swiss Prot. accession number P14020) [Saccharomyces cerevisiae] Length = 267 Score = 74.9 bits (181), Expect = 7e-13 Identities = 58/204 (28%), Positives = 97/204 (47%), Gaps = 45/204 (22%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEI-----PEFVN--EVIVVDDGSKDNTADVA-----KRF 48 ++ SVI+PAY+E+ I + + PE E+I VDD S+D + + + + Sbjct: 3 IEYSVIVPAYHEKLNIKPLTTRLFAGMSPEMAKKTELIFVDDNSQDGSVEEVDALAHQGY 62 Query: 49 GVRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKII------------- 95 VR+I RG +A+ +G AKG +V MDAD QH P+ +PK+ Sbjct: 63 NVRIIVRTNERGLSSAVLKGFYEAKGQYLVCMDADLQHPPETVPKLFESLHDHAFTLGTR 122 Query: 96 -APIIKGDADFVIGKRVIKAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREF 154 AP + D D+ + +RVI + R + R L+ D SGF +++++ Sbjct: 123 YAPGVGIDKDWPMYRRVISSTARMMARPLT--------------IASDPMSGFFGLQKKY 168 Query: 155 LP-----DIESERYEVETEVLIKV 173 L DI S+ +++ E+L K+ Sbjct: 169 LENCNPRDINSQGFKIALELLAKL 192 >emb|CAC11893.1| (AL445065) dolichol-phosphate-mannosyltransferase related protein [Thermoplasma acidophilum] Length = 246 Score = 74.9 bits (181), Expect = 7e-13 Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 25/205 (12%) Query: 1 MKVSVIIPAYNE----EKRIGKVLAEIPEFVNEVIVVDDGSKDNTAD-VAKRFG----VR 51 +++SV+ NE E+ I V + E+IVVDD S D T + +A+R V Sbjct: 3 VQISVVAATLNEIDNIEQFIDGVEGVLKGMEFEIIVVDDNSSDGTKEYLARRMNEDTHVV 62 Query: 52 VIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV 111 VI P G +++ GI+ A G+I++ MDAD QH P IPK+I+ I+ G D V+G R Sbjct: 63 VIENPYRFGMLRSLKLGIEKAGGEIVLVMDADMQHPPSAIPKLISRIVDG-CDIVVGSRY 121 Query: 112 IKAGK-------RPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESER-- 162 + G R + + + F+ L+ + + D SGF A +R+ D + Sbjct: 122 VDGGSAGDRDAFRAALSRGAEFLAHALVPS--SRMTSDPMSGFFAFRRDLRHDFAYRQTF 179 Query: 163 ----YEVETEVLIKVAKKGARIVEV 183 Y + ++I + A++ +V Sbjct: 180 ATADYGAKILLIILAENRHAKVCDV 204 >sp|P54856|DPM1_USTMA DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (DOLICHOL-PHOSPHATE MANNOSE SYNTHASE) (DOLICHYL-PHOSPHATE BETA-D-MANNOSYLTRANSFERASE) >gi|7448313|pir||S71642 dolichyl phosphoryl mannose synthase - smut fungus (Ustilago maydis) >gi|1322289|gb|AAC49401.1| (U54797) dolichyl phosphoryl mannose synthase [Ustilago maydis] Length = 294 Score = 73.7 bits (178), Expect = 2e-12 Identities = 54/217 (24%), Positives = 97/217 (43%), Gaps = 48/217 (22%) Query: 4 SVIIPAYNEEKRIGKVLAEIP---------EFVN-EVIVVDDGSKDNTADV-----AKRF 48 SVI+PA+ E + ++ + E N E+I+VDD S+D + + ++ + Sbjct: 31 SVIVPAFRENLNLRPLVTRLSSAFASQSSSELANTEIIIVDDNSRDGSVETVSALQSEGY 90 Query: 49 GVRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPI---------- 98 VR+I RG +A+ G + A+G ++ MDAD QH P+ +P ++ + Sbjct: 91 NVRIIVATSERGLSSAVVRGFREARGQRMICMDADLQHPPEAVPSLLLALNGQKSFVLGT 150 Query: 99 -----IKGDADFVIGKRVIKAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKRE 153 + D D+ + +R+I +G R L R L++ D SGF I + Sbjct: 151 RYGVGVSMDKDWPLHRRIISSGARMLARPLTS--------------ASDPMSGFFGITKH 196 Query: 154 FL----PDIESERYEVETEVLIKVAKKGARIVEVPVS 186 I ++ +++ ++L+K I EVP S Sbjct: 197 SFHTADHHINAQGFKIALDLLVKSGVHSTDIAEVPFS 233 >pir||S70643 dolichyl-phosphate-mannose synthase precursor - Trypanosoma brucei brucei >gi|1150648|emb|CAA90875.1| (Z54162) dolichyl-phosphate-mannose synthase [Trypanosoma brucei brucei] Length = 267 Score = 73.4 bits (177), Expect = 2e-12 Identities = 55/196 (28%), Positives = 95/196 (48%), Gaps = 24/196 (12%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN--------EVIVVDDGSKDNTADVAKR----- 47 +K S+I+PAY E + + A + + E+++VDD S+D + +V ++ Sbjct: 3 VKYSIIVPAYKECGNLSHLQAGVDRLADDGFSKNEVEMVIVDDNSRDGSVEVVEKVRNEG 62 Query: 48 FGVRVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVI 107 +GVR+ +RG +A+ GI +KG I+ MDAD QH PK +P ++ + K +FV Sbjct: 63 YGVRIEVRTNDRGLSSAVIHGISVSKGSFILVMDADLQHPPKTVPCLLRALEKPGVEFVC 122 Query: 108 GKRV---IKAGKR-PLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPD-----I 158 G R ++ K PL R+ ++ L A+ + D SGF R + + Sbjct: 123 GTRYGAGVEIDKDWPLHRRFISWGARLL--ARPLTPLSDPMSGFFGPSRSMFFNGGREVV 180 Query: 159 ESERYEVETEVLIKVA 174 Y++ E+ +K A Sbjct: 181 NPIGYKIALELFVKCA 196 >pir||S77381 rfbJ protein - Synechocystis sp. (strain PCC 6803) >gi|1652563|dbj|BAA17484.1| (D90906) RfbJ protein [Synechocystis sp.] Length = 318 Score = 73.4 bits (177), Expect = 2e-12 Identities = 50/192 (26%), Positives = 95/192 (49%), Gaps = 10/192 (5%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVNE--VIVVDDGSKDNTADVAKRFGVRVIRLPENR 59 +++V++P NE I +V+ + + + + V D+ S D+TA VA++ G ++R + Sbjct: 10 RLAVLVPCRNEALTITQVVTDFRQQLPNAAIYVYDNCSTDDTATVAQQAGA-IVRYEKQP 68 Query: 60 GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVIKAGKRPL 119 GKG +R + DI + +D D ++ + + ++I +I D V+G R + + Sbjct: 69 GKGNVIRRMFADIEADIYILVDGDNTYEAEAVGRLIDRLINEQLDMVVGARRSEVKDKEA 128 Query: 120 VR---KLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFL---PDIESERYEVETEVLIKV 173 R + N + ++ + ++DD SG+R R F+ P I S +E+ETE+ I Sbjct: 129 YRFGHRSGNQLLKGIVELQFGARLDDMLSGYRIFSRRFVKCFPAI-SNGFEIETELTIHT 187 Query: 174 AKKGARIVEVPV 185 + E PV Sbjct: 188 LELRLPFAEEPV 199 >pir||T34985 probable sugar transferase - Streptomyces coelicolor >gi|3395543|emb|CAA20162.1| (AL031182) putative sugar transferase [Streptomyces coelicolor A3(2)] Length = 478 Score = 72.6 bits (175), Expect = 3e-12 Identities = 54/170 (31%), Positives = 89/170 (51%), Gaps = 14/170 (8%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFG-----V 50 ++SV++P +NE I + + + + E+ VDDGS D T D+ ++ G V Sbjct: 5 QLSVVVPCFNEAAVIERFHSAVENVLGPSNLDYEICYVDDGSTDRTPDLIRQLGFADPRV 64 Query: 51 RVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 R + L N GK +AM G++ ++G +V MDAD QH P+ IP+++ +G D V+ +R Sbjct: 65 RYVVLSRNFGKESAMLAGLRMSRGQAVVLMDADLQHPPELIPRMLELHARG-YDQVVPRR 123 Query: 111 VIKAGKRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIES 160 +AG +VR L + L+R + KV D FR + R + + S Sbjct: 124 -DRAGD-GVVRTLLSRGYYALVRHLMDVKVLDGAGDFRLLSRHAVDTVLS 171 >emb|CAB11300.1| (Z98604) hypothetical protein MLCB2052.02 [Mycobacterium leprae] Length = 277 Score = 71.8 bits (173), Expect = 6e-12 Identities = 58/205 (28%), Positives = 92/205 (44%), Gaps = 24/205 (11%) Query: 3 VSVIIPAYNEEKRI----GKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFG------VRV 52 V VIIP +NE + + G++ PE V++VDDGS D T ++A V Sbjct: 19 VLVIIPTFNELENLPVTHGRLKDAYPEI--HVLIVDDGSPDGTGELADELAQVDPGCTHV 76 Query: 53 IRLPENRGKGAAMREGIKHAKG---DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 + G G A G ++V MDADG H P+++ +++ + G AD IG Sbjct: 77 MHRTTKDGLGTAYLAGFAWGMSRDYSVLVEMDADGSHAPEQLHRLLGAVDAG-ADLAIGS 135 Query: 110 RVIKAG---KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIE-----SE 161 R + G P R + R + V D +G+RA +RE L I+ S+ Sbjct: 136 RYVNGGTVRNWPWQRLALSKTANKYSRLALGIDVHDITAGYRAYRREVLEAIDLDSVASK 195 Query: 162 RYEVETEVLIKVAKKGARIVEVPVS 186 Y + ++ + G I+EVP++ Sbjct: 196 GYCFQIDLTWRTVNNGFVIIEVPIT 220 >emb|CAB72208.1| (AL138851) putative bi-functional transferase/deacetylase [Streptomyces coelicolor A3(2)] Length = 734 Score = 70.6 bits (170), Expect = 1e-11 Identities = 41/100 (41%), Positives = 60/100 (60%), Gaps = 6/100 (6%) Query: 3 VSVIIPAYNEEKRIGKVLAEI--PEFVNEVIVVDDGSKDNTADVAKRFG---VRVIRLPE 57 V+V++PAYNE K I + + + EVIV+DDGS D TA + + G VRVIR Sbjct: 362 VTVLVPAYNEAKCIENTVRSLVASDHPVEVIVIDDGSSDGTARIVEGLGLPGVRVIR-QL 420 Query: 58 NRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAP 97 N GK AA+ G+ +A+ DI+V MD D +P + +++ P Sbjct: 421 NAGKPAALNRGLANARYDIVVMMDGDTVFEPSTVRELVQP 460 >gb|AAG19351.1| (AE005030) galactosyltransferase homolog; Gst [Halobacterium sp. NRC-1] Length = 229 Score = 70.2 bits (169), Expect = 2e-11 Identities = 51/187 (27%), Positives = 90/187 (47%), Gaps = 6/187 (3%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVNEV--IVVDDGSKDNTADVAKRFGVRVIRLPENRG 60 V+V + YNE I VL +I + ++ +V DGS D T ++A+ G VI E +G Sbjct: 11 VTVAMGTYNEAAAIDTVLTDIADATDDRARVVCVDGSSDRTPEIAREHGATVIE-QEPQG 69 Query: 61 KGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRVI-KAGKRPL 119 G A+ + A +++ D D + + IP +A I +G D V G R+ A P Sbjct: 70 YGVAVAAALDAADTPVVITTDCDNTYPMERIPAFLARINEG-YDVVSGDRLYWGADTMPA 128 Query: 120 VRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIE-SERYEVETEVLIKVAKKGA 178 +L N + + ++V DT +G RA + + I+ ++ + E+LI+ + Sbjct: 129 FNRLGNAAFAAITSLLVGERVHDTTTGMRAYRAPVIDAIDWTQNTGLSAELLIRPLCRNY 188 Query: 179 RIVEVPV 185 ++E P+ Sbjct: 189 DVIEEPI 195 >sp|O21943|GTRB_BPSF2 BACTOPRENOL GLUCOSYL TRANSFERASE >gi|2465415|gb|AAC39272.1| (AF021347) bactoprenol glucosyl transferase [bacteriophage SfII] Length = 309 Score = 69.5 bits (167), Expect = 3e-11 Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 15/171 (8%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFGVR--- 51 MK+S+++P +NEE+ I + EF E++ ++DGSKD T + V Sbjct: 1 MKISLVVPVFNEEEAIPVFYKTVREFQELKPYEVEIVFINDGSKDATESIINALAVSDPL 60 Query: 52 --VIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 + N GK A+ G+ HA GD ++ +D D Q + IP +I G AD V+ K Sbjct: 61 VVPLSFTRNFGKEPALFAGLDHASGDAVIPIDVDLQDPIEVIPHLIEKWQAG-ADMVLAK 119 Query: 110 RVIKAGKRPLVRKLSNFITTTLIRAKIK-QKVDDTQSGFRAIKREFLPDIE 159 R ++ L RK + + + KI K+++ FR + RE + +I+ Sbjct: 120 RSDRSTDGRLKRKTAEWFYK--LHNKISTPKIEENVGDFRLMSREVVENIK 168 >sp|O22007|GTRB_BPSF5 BACTOPRENOL GLUCOSYL TRANSFERASE >gi|2465475|gb|AAB72133.1| (U82619) orf5 [Shigella flexneri bacteriophage V] Length = 307 Score = 69.5 bits (167), Expect = 3e-11 Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 15/171 (8%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFGVR--- 51 MK+S+++P +NEE+ I + EF E++ ++DGSKD T + V Sbjct: 1 MKISLVVPVFNEEEAIPVFYKTVREFQELKPYEVEIVFINDGSKDATESIINALAVSDPL 60 Query: 52 --VIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 + N GK A+ G+ HA GD ++ +D D Q + IP +I G AD V+ K Sbjct: 61 VVPLSFTRNFGKEPALFAGLDHASGDAVIPIDVDLQDPIEVIPHLIEKWQAG-ADMVLAK 119 Query: 110 RVIKAGKRPLVRKLSNFITTTLIRAKIK-QKVDDTQSGFRAIKREFLPDIE 159 R ++ L RK + + + KI K+++ FR + RE + +I+ Sbjct: 120 RSDRSTDGRLKRKTAEWFYK--LHNKISTPKIEENVGDFRLMSREVVENIK 168 >pir||B70945 hypothetical protein Rv2051c - Mycobacterium tuberculosis (strain H37RV) >gi|2896788|emb|CAA17265.1| (AL021899) hypothetical protein Rv2051c [Mycobacterium tuberculosis] Length = 874 Score = 69.5 bits (167), Expect = 3e-11 Identities = 54/204 (26%), Positives = 91/204 (44%), Gaps = 20/204 (9%) Query: 2 KVSVIIPAYNEEKRIGKVLAEIPEFVN--EVIVVDDGSKDNTADVAKRFG------VRVI 53 +V VIIP +NE + + + + + V+VVDD S D T +A V+ Sbjct: 611 RVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPDGTGQLADELAQADPGRTHVM 670 Query: 54 RLPENRGKGAAMREGIKHAKG---DIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 G GAA G ++V MDADG H P+++ +++ + G AD IG R Sbjct: 671 HRTAKNGLGAAYLAGFAWGLSREYSVLVEMDADGSHAPEQLQRLLDAVDAG-ADLAIGSR 729 Query: 111 VIKAG---KRPLVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREF-----LPDIESER 162 + G P R + + T R + + D +G+RA +RE L ++S+ Sbjct: 730 YVAGGTVRNWPWRRLVLSKTANTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKG 789 Query: 163 YEVETEVLIKVAKKGARIVEVPVS 186 Y + ++ + G + EVP++ Sbjct: 790 YCFQIDLTWRTVSNGFVVTEVPIT 813 >gb|AAC69672.1| (AF019746) putative beta1,3-glucosyltransferase WaaV [Escherichia coli] Length = 327 Score = 69.5 bits (167), Expect = 3e-11 Identities = 40/101 (39%), Positives = 59/101 (57%), Gaps = 11/101 (10%) Query: 3 VSVIIPAYNEEKRIGKVLAEI-----PEFVNEVIVVDDGSKDNTADVAKRFGVRVIRL-- 55 VS+IIP YN I + L ++ P F E+++V+DGSKDNT++V + +G+ RL Sbjct: 8 VSIIIPTYNSSDYITETLTKLEKQTYPNF--EIVIVNDGSKDNTSNVLREYGLTHSRLII 65 Query: 56 --PENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKI 94 EN G +A GI+ A+G I FMD D + DP + K+ Sbjct: 66 INKENGGVSSARNTGIRKAQGQFICFMDDDDEIDPNYLLKM 106 >pir||D83201 probable glycosyl transferase PA3553 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949705|gb|AAG06941.1|AE004776_4 (AE004776) probable glycosyl transferase [Pseudomonas aeruginosa] Length = 339 Score = 69.1 bits (166), Expect = 4e-11 Identities = 39/111 (35%), Positives = 68/111 (61%), Gaps = 12/111 (10%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEF------VNEVIVVDDGSKDNTADV----AKRFGVRV 52 VSV+IP YNEE + ++L E+++VDDGS+D +A++ A+R G V Sbjct: 9 VSVVIPVYNEEASLPELLRRTEAACLELGRAFEIVLVDDGSRDRSAELLQAAAERDGSAV 68 Query: 53 IRLPENR--GKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKG 101 + + NR G+ AA+ G + ++GD+++ +DAD Q+ P+EIP+++ +G Sbjct: 69 VAVILNRNYGQHAAILAGFEQSRGDLVITLDADLQNPPEEIPRLVERAAQG 119 >pir||S76171 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1653517|dbj|BAA18430.1| (D90914) dolichyl-phosphate-mannose synthase [Synechocystis sp.] Length = 390 Score = 68.3 bits (164), Expect = 7e-11 Identities = 56/193 (29%), Positives = 97/193 (50%), Gaps = 21/193 (10%) Query: 3 VSVIIPAYNEEKRIGKVLAEIPEFVN-------EVIVVDDGSKDNTADVAKRFG-----V 50 +S+++P YNE + I ++ + + + E+IVVDD S D T A + Sbjct: 26 LSLVLPTYNEGENIQAMVTTLVKLLENRWSGQYELIVVDDDSPDLTWQKAFNLSDTYPQL 85 Query: 51 RVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 RVIR E RG A+ G + A+G+ + +DAD QH P+ + ++A + +G AD + R Sbjct: 86 RVIRRTEGRGLSTAVIRGWQEARGNFLGVIDADLQHPPQVLLALLAEMERG-ADLAVASR 144 Query: 111 VIKAG---KRPLVRKLSN---FITTTLIRAKIKQKVDDTQSGFRAIKREFLPDIESERYE 164 G + LVR+L + + LI ++ ++ D SGF ++R+ + D Sbjct: 145 HQSGGGVSQWSLVRRLLSRGAQMLGLLILPEVIGRLSDPMSGFFLVRRQAIADCPLS--P 202 Query: 165 VETEVLIKVAKKG 177 V ++LI+V +G Sbjct: 203 VGYKILIEVTARG 215 >sp|P77293|GTRB_ECOLI BACTOPRENOL GLUCOSYL TRANSFERASE HOMOLOG FROM PROPHAGE CPS-53 >gi|7446788|pir||D65008 hypothetical protein b2351 - Escherichia coli (strain K-12) >gi|1788692|gb|AAC75410.1| (AE000323) putative glycan biosynthesis enzyme [Escherichia coli K12] >gi|1799748|dbj|BAA16210.1| (D90865) DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (EC 2.4.1.83) (DOLICHOL- PHOSPHATE MANNOSE SYNTHASE) (DOLICHYL-PHOSPHATE BETA-D- MANNOSYLTRANSFERASE). [Escherichia coli] >gi|1799756|dbj|BAA16217.1| (D90866) DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (EC 2.4.1.83) (DOLICHOL- PHOSPHATE MANNOSE SYNTHASE) (DOLICHYL-PHOSPHATE BETA-D- MANNOSYLTRANSFERASE). [Escherichia coli] Length = 306 Score = 68.3 bits (164), Expect = 7e-11 Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 15/171 (8%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFGVR--- 51 MK+S+++P +NEE+ I + EF E++ ++DGSKD T + V Sbjct: 1 MKISLVVPVFNEEEAIPIFYKTVREFEELKSYEVEIVFINDGSKDATESIINALAVSDPL 60 Query: 52 --VIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 + N GK A+ G+ HA GD I+ +D D Q + IP +I G AD V+ K Sbjct: 61 VVPLSFTRNFGKEPALFAGLDHATGDAIIPIDVDLQDPIEVIPHLIEKWQAG-ADMVLAK 119 Query: 110 RVIKAGKRPLVRKLSNFITTTLIRAKIKQ-KVDDTQSGFRAIKREFLPDIE 159 R ++ L RK + + + KI K+++ FR + R+ + +I+ Sbjct: 120 RSDRSTDGRLKRKTAEWFYK--LHNKISNPKIEENVGDFRLMSRDVVENIK 168 >sp|Q9T1D6|GTRB_BPSFX BACTOPRENOL GLUCOSYL TRANSFERASE >gi|6652754|gb|AAF22454.1|AF056939_2 (AF056939) bactoprenol glucose transferase [bacteriophage SfX] Length = 305 Score = 68.3 bits (164), Expect = 7e-11 Identities = 49/171 (28%), Positives = 83/171 (47%), Gaps = 15/171 (8%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFGVR--- 51 MK+S+++P +NEE+ I + EF E++ ++DGSKD T + V Sbjct: 1 MKISLVVPVFNEEEAIPIFYKTVREFEELKPYEVEIVFINDGSKDATESIINALAVSDPL 60 Query: 52 --VIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 + N GK A+ G+ H GD ++ +D D Q + IP++I G AD V+ K Sbjct: 61 VVPLSFTRNFGKEPALFAGLDHTTGDAVIPIDVDLQDPIEVIPRLIEKWQAG-ADMVLAK 119 Query: 110 RVIKAGKRPLVRKLSNFITTTLIRAKIK-QKVDDTQSGFRAIKREFLPDIE 159 R ++ L RK + + + KI K+++ FR + RE + +I+ Sbjct: 120 RSDRSTDGRLKRKTAEWFYK--LHNKISTPKIEENVGDFRLMSREVVENIK 168 >emb|CAB81849.1| (AL161691) putative glucosyltransferase [Streptomyces coelicolor A3(2)] Length = 345 Score = 68.3 bits (164), Expect = 7e-11 Identities = 45/120 (37%), Positives = 65/120 (53%), Gaps = 13/120 (10%) Query: 3 VSVIIPAYNEEK-------RIGKVLAEIPEFVNEVIVVDDGSKDNTADVAKRFGV----- 50 +SV+IP +NEE R+ VL E+ +EV+ VDDGS D TA++ F + Sbjct: 15 LSVVIPMFNEEDVLPALVTRLRPVLTELG-VPHEVVAVDDGSGDRTAELLDAFRLGWPEL 73 Query: 51 RVIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKR 110 RV+ L N G AA+ G+ A+G +V +DAD Q P++IP ++A D V G R Sbjct: 74 RVVALRRNSGHQAALTAGLDRARGAYVVSLDADLQDPPEKIPDMLALARAEGLDIVYGVR 133 >pir||D69769 cellulose synthase homolog ydaM - Bacillus subtilis >gi|1881240|dbj|BAA19267.1| (AB001488) FUNCTION UNKNOWN, SIMILAR PRODUCT IN MANY BACTERIA. [Bacillus subtilis] >gi|2632730|emb|CAB12237.1| (Z99106) similar to cellulose synthase [Bacillus subtilis] Length = 420 Score = 67.9 bits (163), Expect = 9e-11 Identities = 49/135 (36%), Positives = 70/135 (51%), Gaps = 15/135 (11%) Query: 2 KVSVIIPAYNEEKRIGKVLAEI-----PEFVNEVIVVDDGSKDNTADVAKRFGVR----- 51 KVSV+IPA+NEE I + L + P+ E+IVV+D S D T D+ F + Sbjct: 50 KVSVLIPAHNEEVVIRQTLKAMVNLYYPKDRLEIIVVNDNSSDRTGDIVNEFSEKYDFIK 109 Query: 52 -VIRLPENRGKG--AAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGD-ADFVI 107 VI P N GKG +A+ G + GD+I DAD + + ++ ++ + A V+ Sbjct: 110 MVITKPPNAGKGKSSALNSGFAESNGDVICVYDADNTPEKMAVYYLVLGLMNDEKAGAVV 169 Query: 108 GK-RVIKAGKRPLVR 121 GK RVI A K L R Sbjct: 170 GKFRVINAAKTLLTR 184 >gb|AAF09026.1| (AF139596) GtrBI [Shigella flexneri] Length = 306 Score = 67.9 bits (163), Expect = 9e-11 Identities = 49/171 (28%), Positives = 83/171 (47%), Gaps = 15/171 (8%) Query: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVN------EVIVVDDGSKDNTADVAKRFGVR--- 51 MK+S+++P +NEE+ I + EF E++ ++DGSKD T + V Sbjct: 1 MKISLVVPVFNEEEAIPVFYKTVREFQELKPYEVEIVFINDGSKDATESIINALAVSDPL 60 Query: 52 --VIRLPENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGK 109 + N GK A+ G+ HA GD ++ +D D Q + IP +I G A+ V+ K Sbjct: 61 VVPLSFTRNFGKEPALFAGLDHASGDAVIPIDVDLQDPIEVIPHLIEKWQAG-AEMVLAK 119 Query: 110 RVIKAGKRPLVRKLSNFITTTLIRAKIK-QKVDDTQSGFRAIKREFLPDIE 159 R ++ L RK + + + KI K+++ FR + RE + +I+ Sbjct: 120 RSDRSTDGRLKRKTAEWFYK--LHNKISTPKIEENVGDFRLMSREVVENIK 168 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.322 0.142 0.392 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 73060212 Number of Sequences: 2977 Number of extensions: 2979913 Number of successful extensions: 7988 Number of sequences better than 1.0e-10: 87 Number of HSP's better than 0.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 78 Number of HSP's that attempted gapping in prelim test: 7787 Number of HSP's gapped (non-prelim): 89 length of query: 211 length of database: 189,106,746 effective HSP length: 56 effective length of query: 155 effective length of database: 155,591,474 effective search space: 24116678470 effective search space used: 24116678470 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 163 (67.9 bits)