BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB2014 (moeA-2) DE:molybdenum cofactor biosynthesis protein
(moeA-2)
         (395 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PA...   782  0.0
pir||G71044 probable molybdopterin biosynthesis moeA protein - P...   660  0.0
gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [A...   298  7e-80
pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacte...   291  1e-77
pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PA...   279  3e-74
gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [A...   273  3e-72
pir||B71173 probable molybdopterin biosynthesis moea protein - P...   264  2e-69
sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN...   260  2e-68
pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex...   237  1e-61
sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN...   237  2e-61
pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Meth...   236  4e-61
emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (m...   226  5e-58
dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus ...   217  1e-55
dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis prot...   216  3e-55
gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis prote...   211  1e-53
gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus]              210  2e-53
pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus s...   210  2e-53
emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (m...   203  3e-51
sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   200  3e-50
pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [impo...   192  4e-48
sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   192  6e-48
pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imp...   186  4e-46
sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   185  1e-45
emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri]                 182  8e-45
emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [...   180  2e-44
pir||G70829 probable molybdenum cofactor biosynthesis protein - ...   177  2e-43
gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis prote...   176  3e-43
pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [...   174  1e-42
pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [...   173  3e-42
sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   168  8e-41
gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulf...   167  2e-40
sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN L...   164  2e-39
dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens]            164  2e-39
gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens]           164  2e-39
gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|C...   164  2e-39
gi|11435181 gephyrin [Homo sapiens]                                   164  2e-39
gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [A...   162  6e-39
pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [...   160  3e-38
pir||T46858 molybdenum cofactor biosynthesis protein A [imported...   157  2e-37
emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes]      157  3e-37
pir||T44851 molybdopterin co-factor synthesis protein moeA [impo...   156  3e-37
sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   155  8e-37
gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus]          153  3e-36
pir||A81359 probable molybdopterin biosynthesis protein Cj0857c ...   152  5e-36
sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MO...   142  8e-33
gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynth...   138  1e-31
emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus]      134  1e-30
pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiod...   129  6e-29
gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulf...   128  1e-28
emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sul...   128  1e-28
pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elega...   128  1e-28
pir||T36508 probable molybdenum cofactor biosynthesis protein - ...   119  5e-26
sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   114  2e-24
sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   111  1e-23
pir||T45454 probable molybdenum cofactor biosynthesis protein [i...   110  2e-23
pir||G71966 molybdopterin biosynthesis protein - Helicobacter py...   108  2e-22
pir||F72773 probable molybdopterin biosynthesis protein APE0177 ...   107  3e-22
pir||D64541 molybdopterin biosynthesis protein - Helicobacter py...   105  8e-22
emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophil...    98  1e-19
emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaste...    98  1e-19
sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAM...    98  2e-19
pir||H72739 probable molybdopterin biosynthesis moeA protein APE...    96  7e-19
pir||T42407 gephyrin homolog - Caenorhabditis elegans >gi|281122...    91  2e-17

>pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PAB2014 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5457952|emb|CAB49442.1| (AJ248284) molybdenum
           cofactor biosynthesis protein (moeA-2) [Pyrococcus
           abyssi]
           Length = 395
           
 Score =  782 bits (1998), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60
           MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY
Sbjct: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60

Query: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120
           AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM
Sbjct: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120

Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180
           VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR
Sbjct: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180

Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240
           KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR
Sbjct: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240

Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV 300
           EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV
Sbjct: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV 300

Query: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK 360
           AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK
Sbjct: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK 360

Query: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
           GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY
Sbjct: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395


>pir||G71044 probable molybdopterin biosynthesis moeA protein - Pyrococcus
           horikoshii >gi|3258076|dbj|BAA30759.1| (AP000006) 396aa
           long hypothetical molybdopterin biosynthesis moeA
           protein [Pyrococcus horikoshii]
           Length = 396
           
 Score =  660 bits (1685), Expect = 0.0
 Identities = 316/395 (80%), Positives = 366/395 (92%)

Query: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60
           MEFKKL+PYREAL LLL+D+ EI+D E VPL EA+ RVLA+DI++EFD+PPFDR+AVDGY
Sbjct: 2   MEFKKLVPYREALKLLLDDINEIEDTEKVPLREAVGRVLAEDIVTEFDIPPFDRAAVDGY 61

Query: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120
           A+RAEDTFQAREY+PIEL VIEEVPAG   K +VT+G AIKVLTG +IP+GANAVIMQEM
Sbjct: 62  AIRAEDTFQAREYNPIELTVIEEVPAGNVAKEEVTTGKAIKVLTGTRIPKGANAVIMQEM 121

Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180
           VKREG+KIYVLRPVAPGQN+AF GEDVKKGEV+LRKGTILRPQD+AMLKALGIK VPVK 
Sbjct: 122 VKREGDKIYVLRPVAPGQNIAFTGEDVKKGEVVLRKGTILRPQDVAMLKALGIKKVPVKV 181

Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240
           KP+VGIIITGSEL+EEPSE+ F+EGKIVETNSIML+ LV KFFGEPILYGV+PD+E  I+
Sbjct: 182 KPKVGIIITGSELIEEPSEEGFKEGKIVETNSIMLQGLVEKFFGEPILYGVLPDDESIIK 241

Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV 300
           E ++KAK ECD+VL+TGGSAFGDKDYAH+FV LLFHGTTIKPGRP GYGE+VFIMSGYPV
Sbjct: 242 ETLEKAKNECDIVLITGGSAFGDKDYAHKFVNLLFHGTTIKPGRPFGYGEKVFIMSGYPV 301

Query: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK 360
           +VFAQF+LFVKHALAKMVGA++YEVK++AIL+DD+PSQLGR+EF+K+ Y +G A+VIKKK
Sbjct: 302 SVFAQFNLFVKHALAKMVGAQNYEVKVKAILQDDIPSQLGRYEFIKIYYENGIARVIKKK 361

Query: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
           GSGI+SSL+ SNAYLE+PEDSEGYRRGEEVWITLY
Sbjct: 362 GSGILSSLLASNAYLEIPEDSEGYRRGEEVWITLY 396


>gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [Archaeoglobus
           fulgidus] >gi|7429691|pir||B69366 molybdenum cofactor
           biosynthesis protein (moeA-2) homolog - Archaeoglobus
           fulgidus >gi|2649666|gb|AAB90308.1| (AE001039)
           molybdenum cofactor biosynthesis protein (moeA-2)
           [Archaeoglobus fulgidus]
           Length = 414
           
 Score =  298 bits (755), Expect = 7e-80
 Identities = 173/397 (43%), Positives = 248/397 (61%), Gaps = 19/397 (4%)

Query: 11  EALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQA 70
           EAL  LL  +  ++  E V +     RVLA+DI++ FDVP F+R+A+DGYAV+AEDTF A
Sbjct: 15  EALYRLLKKIKALE-TEDVSVYNLQGRVLAEDIVAGFDVPKFNRAAMDGYAVKAEDTFGA 73

Query: 71  REYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYV 130
              +PI L++   V  GE PK+ V SG A++++TGA +PEG NAV+M E  +  G  + V
Sbjct: 74  SVSNPIMLQLAGSVEIGEVPKVVVESGMAVRIMTGAMMPEGTNAVVMLEHTRLNGNFVEV 133

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
           L+ V P +NV+  GED+  GEV+ RKG IL+PQD  ++ +LGI+SV V RKPRV +I TG
Sbjct: 134 LKSVTPMKNVSRVGEDIAAGEVVFRKGEILQPQDAGVIASLGIESVRVYRKPRVAVITTG 193

Query: 191 SELVE--EPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKR 248
           +EL E  EP E A    KI  +N+ M+ + + +F  E I  G+  D+E+++R  ++KA  
Sbjct: 194 NELAEVGEPLEGA----KIYNSNNPMICNALLEFGFEAISLGIARDDEEELRNKLQKA-L 248

Query: 249 ECDLVLVTGGSAFGDK----DYAHRFVKLLFHGTTIKPGRPIG----YGERVFIMSGYPV 300
           E D  ++TGG++ G K    D    F +++FHG ++KPG P G     G+ VF++ G P 
Sbjct: 249 EFDAAVITGGTSVGAKDLVPDVVGEFGEIVFHGVSMKPGMPTGAAVVEGKPVFMLPGSPA 308

Query: 301 AVFAQFHLFVKHALAKMVGARDYEVK---LRAILEDDVPSQLGRHEFVKVLYRDGKAKVI 357
           A    F+ F   AL +M+  R    K    + +L+  +PS++G    V+VL+ DGK   I
Sbjct: 309 AALLGFYTFAIPALYRMMNVRIIARKWSRQKGVLQGRIPSEIGVRSNVRVLWEDGKVYPI 368

Query: 358 KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394
           +  GSGI+SS V +NA L VPED EGY  GEEV +TL
Sbjct: 369 RISGSGILSSFVRANALLVVPEDKEGYEEGEEVEVTL 405


>pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622477|gb|AAB85846.1| (AE000899) molybdenum
           cofactor biosynthesis MoeA [Methanobacterium
           thermoautotrophicum]
           Length = 404
           
 Score =  291 bits (736), Expect = 1e-77
 Identities = 169/407 (41%), Positives = 252/407 (61%), Gaps = 20/407 (4%)

Query: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60
           M   +L+P R+A  +L ++     + E V L EA +RVLA DI+S FD PPFDRSA+DGY
Sbjct: 1   MFLSELLPVRDAFRIL-DENQRFTEPETVDLLEAYHRVLADDIVSRFDSPPFDRSAMDGY 59

Query: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120
           AVRAEDTF +   +P  L+V + + AGE   + V  G A+++ TGA IP GA+AV+M+E 
Sbjct: 60  AVRAEDTFGSSPGNPSTLRVTDSIGAGEVSGVDVGHGEAVRIATGAPIPAGADAVVMEEY 119

Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180
             ++G  I VLRPVAP +NVA  GEDV++G  +LR+GT++RPQ++AM  + G   V V R
Sbjct: 120 TLQDGPDIRVLRPVAPSENVAPAGEDVRRGVTVLREGTLMRPQEIAMAASAGYSKVRVFR 179

Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFG--EPILYGVIPDEEDK 238
           +P V +I+TG+ELV +PS+D  E GK+  +N   L +LV    G  +P+    +PD+ D 
Sbjct: 180 RPSVKVIVTGNELV-DPSDD-LEPGKVPNSNLYTLNALVESAGGSADPV---HLPDDIDT 234

Query: 239 IREAIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGYG----E 290
           + E I+ +  E D+++ TGG+A    D     V    ++LFHG  ++PG+P+ +G     
Sbjct: 235 VGEEIESSASEYDVIITTGGTAISRGDVVVDAVDGLGEVLFHGVALRPGKPVAFGMVSET 294

Query: 291 RVFIMSGYPVAVFAQFHLFVKHALAKM--VGARDYEVKLRAILEDDVPSQLGRHEFVKVL 348
            VF++SGYPVA   QF +F ++ L +M  +  R   VK R      V S  GR ++++  
Sbjct: 295 PVFMLSGYPVAAMVQFDVFARYYLLRMQHLDYRHRAVKRRC--RAKVASGPGRTDYLRAW 352

Query: 349 YRDGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
             D + + ++ +GSGII S+V SNAY+ + E+ EG   GEE  + L+
Sbjct: 353 ADDEEVEPVQSRGSGIIRSMVGSNAYIVIDENLEGISAGEECDVLLF 399


>pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PAB1436 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458839|emb|CAB50326.1| (AJ248287) molybdenum
           cofactor biosynthesis protein (moeA-1) [Pyrococcus
           abyssi]
           Length = 402
           
 Score =  279 bits (707), Expect = 3e-74
 Identities = 159/403 (39%), Positives = 241/403 (59%), Gaps = 12/403 (2%)

Query: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60
           M F K++P   AL ++ N  T     E V L EAL R++A+DI S  D+PPFDR+ VDGY
Sbjct: 1   MAFLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59

Query: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120
           AVRAEDTF A E +PI+LKV+ E+ AGE PK+++  G  + + TGA +P+ A+AVI  E 
Sbjct: 60  AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119

Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180
           V+R G++I + +P  PG  V  KG D+ KG +++RKG  L  +  A+L A+G++ V V R
Sbjct: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179

Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240
           KP+V II TG+E+V   SE   + G+I + N   L   V++  GE I  G+  D+ + ++
Sbjct: 180 KPKVAIISTGNEIVLPGSE--LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237

Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGE----RV 292
           E I++  R  D+V+++GG++ G +D     ++ L     HG  I+PG+P   GE     V
Sbjct: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297

Query: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352
           F + GYP +    F L V   L + +G      K++A L+  + S  GR +F+ V    G
Sbjct: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357

Query: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
            A  I  KGSG ++S ++++ ++E+PE  E    GEEV +TL+
Sbjct: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399


>gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [Archaeoglobus
           fulgidus] >gi|7429678|pir||C69366 molybdenum cofactor
           biosynthesis protein (moeA-1) homolog - Archaeoglobus
           fulgidus >gi|2649665|gb|AAB90307.1| (AE001039)
           molybdenum cofactor biosynthesis protein (moeA-1)
           [Archaeoglobus fulgidus]
           Length = 654
           
 Score =  273 bits (690), Expect = 3e-72
 Identities = 156/407 (38%), Positives = 243/407 (59%), Gaps = 16/407 (3%)

Query: 3   FKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAV 62
           F+ ++   EA  LL N  +  +  E VPL  A  RVLA+D+ +  DVPPFDR+ +DGYAV
Sbjct: 5   FRDVVTVDEARGLLFNHFSPRRKTEVVPLHLAAGRVLAKDVYALTDVPPFDRATMDGYAV 64

Query: 63  RAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK 122
           RAEDTF+A E SP+ LKV+  V AG+ P+++V SG A+++ TGA +P+GANAV+M E  +
Sbjct: 65  RAEDTFEAEEDSPVTLKVVGTVEAGKRPELEVESGKAVEIATGAMMPKGANAVVMVEFTR 124

Query: 123 REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182
           R  ++I + +PV+PG+NV + G DV  GE+I R+GT L  +++ ++ A GI  V V  +P
Sbjct: 125 RREDEIDIFKPVSPGENVMYAGSDVMAGELIAREGTELTHREIGVMAACGISEVEVYCRP 184

Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242
           +V II TG+ELV +P E    EGKI + NS  + + V +  GE IL G+  D E+++R  
Sbjct: 185 KVAIISTGNELV-KPGE-RLGEGKIYDVNSYSIAAAVEENGGEAILMGIARDNEEEMRSI 242

Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRP----IGYGERVF 293
           I KA RE D+V+ +G ++ G  D  +R +      ++ HG  IKPG+P    +   + +F
Sbjct: 243 IAKALREADIVITSGSTSAGAGDVMYRILDDFHPGVIVHGIAIKPGKPAVIAVSDSKPIF 302

Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARDYE-VKLRAILEDDVPSQLGRHEFVKVLYRDG 352
            + GYP +    F + V   + ++ G R+    K+RA L   V S  GR E++ V   +G
Sbjct: 303 GLPGYPTSAMTVFEVIVAPIIRELAGRRESSGAKVRARLAIKVFSAEGRREYLPVNVVEG 362

Query: 353 ----KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
                A  +    SG +++   ++ ++E+PE+      G+EV + L+
Sbjct: 363 AEGYSAYPVSGSYSGAVTAFAFTDGFVEIPENVVMLEEGDEVEVKLF 409


>pir||B71173 probable molybdopterin biosynthesis moea protein - Pyrococcus
           horikoshii >gi|3256988|dbj|BAA29671.1| (AP000002) 402aa
           long hypothetical molybdopterin biosynthesis moea
           protein [Pyrococcus horikoshii]
           Length = 402
           
 Score =  264 bits (667), Expect = 2e-69
 Identities = 158/403 (39%), Positives = 236/403 (58%), Gaps = 12/403 (2%)

Query: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60
           M F K++P  +AL ++ +       +E VP+++ L R+ A+DI S  DVPPFDR+ VDGY
Sbjct: 1   MAFLKVVPLEKALEVVQSFKIS-PGIEEVPIEKGLGRIAAEDIYSPIDVPPFDRATVDGY 59

Query: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120
           AVRAEDTF A E SP+ LKVI  V AGE PK K+  G A  + TGA +P  A+AVI  E 
Sbjct: 60  AVRAEDTFMASEASPVRLKVIGSVHAGEEPKFKLGKGEAAYISTGAMLPGNADAVIQFED 119

Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180
           V+R   +I + +P  PG  V  KG D++KG ++++KG  L  +  A+L A+GI  V V R
Sbjct: 120 VERVNGEILIYKPAYPGLGVMKKGIDIEKGRLLVKKGERLGFKQTALLSAVGINKVKVFR 179

Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240
           KP+V +I TG+E+V  P  +  + G+I + N   L   +++  GE I  GV  D+++ ++
Sbjct: 180 KPKVAVISTGNEIV--PPGNELKPGQIYDINGRALCDAINELGGEGIFMGVARDDKESLK 237

Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRP--IGY--GERV 292
             I+KA    D+V+++GG++ G KD     ++ L     HG  I+PG+P  IG   G+ V
Sbjct: 238 ALIEKAVNVGDVVVISGGASGGTKDLTASVIEELGEVKVHGIAIQPGKPTIIGVIKGKPV 297

Query: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352
           F + GYP +    F L V   L + +G      K  A L+  V S  GR +F+ V   +G
Sbjct: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKIGKKVARLKHKVFSVKGRRQFLPVKL-EG 356

Query: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
              V   KGSG ++S ++++ ++E+PE  E    GEEV +TL+
Sbjct: 357 DLAVPILKGSGAVTSFIDADGFVEIPETVESLDEGEEVEVTLF 399


>sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0666
           >gi|2129130|pir||B64383 molybdenum cofactor biosynthesis
           protein moeA homolog - Methanococcus jannaschii
           >gi|1591380|gb|AAB98661.1| (U67514) molybdenum cofactor
           biosynthesis protein (moeA) [Methanococcus jannaschii]
           Length = 398
           
 Score =  260 bits (657), Expect = 2e-68
 Identities = 159/409 (38%), Positives = 248/409 (59%), Gaps = 35/409 (8%)

Query: 4   KKLMPYREALTLLLNDVTEIQD----VEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDG 59
           K LMP + A  ++   ++E  D    V+ V + EALNR+ A+DI +  D+P F+++A+DG
Sbjct: 5   KNLMPLKSAEKIVFEKLSEYLDENKKVKEVDIVEALNRISAEDIKAPIDLPYFNKAAMDG 64

Query: 60  YAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQE 119
           YAV AEDTF A E +PI L + +    G+    ++T G A K+ TG K+P+ ANAV+M+E
Sbjct: 65  YAVIAEDTFGASETNPIILNLAD----GD----EITYGEAKKIFTGDKLPKNANAVVMKE 116

Query: 120 MVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVK 179
                 + + V + V P +NV+  GEDVKKG+V+L+KG I+ P  L ML +LGIK + V 
Sbjct: 117 FCNEVDDFVEVYKTVHPNENVSRIGEDVKKGDVVLKKGEIINPYHLNMLASLGIKKIKV- 175

Query: 180 RKPRVGIIITGSEL-----VEEPSEDAFE-EGKIVETNSIMLKSLVHKFFGEPILYGVIP 233
                GII TG EL     + +  ED  + +GKI+ +NS ML  LV        +Y ++ 
Sbjct: 176 YDLSFGIISTGDELINLDEIRDIEEDISKLDGKIINSNSYMLYGLVKNLGFNAKIYDIVK 235

Query: 234 DEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYG 289
           D+++K+++AIK A  E D +L+TGG++  ++D     V+    ++ HG  I+PG+P G+G
Sbjct: 236 DDKEKLKKAIKTALSENDALLITGGTSVSERDITVETVRELGDVIVHGVNIRPGKPFGFG 295

Query: 290 ----ERVFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFV 345
               + VF++SGYPVA   QF LF++    +         K+   L+ ++ S+LGR +FV
Sbjct: 296 IINDKPVFMLSGYPVASAVQFELFIQRFFIE-------RKKVTLPLKRNMASELGRVDFV 348

Query: 346 KVLYRDGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394
           +V   D + + I+  GSG+ISSL++S+ Y+ +PE+ EGY +GE V + L
Sbjct: 349 RVKV-DIEVEPIRITGSGVISSLIKSDGYILIPENVEGYEKGELVDVYL 396


>pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex aeolicus
           >gi|2982782|gb|AAC06407.1| (AE000670) molybdenum
           cofactor biosynthesis protein A [Aquifex aeolicus]
           Length = 402
           
 Score =  237 bits (599), Expect = 1e-61
 Identities = 154/408 (37%), Positives = 232/408 (56%), Gaps = 23/408 (5%)

Query: 4   KKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVR 63
           K L P  EAL ++L +V  ++  E V + EAL RVLA+D++S+ D P FD SA+DGYAVR
Sbjct: 2   KNLTPLEEALKIVLENVKPLES-ERVFIHEALGRVLAEDVVSDTDKPLFDNSAMDGYAVR 60

Query: 64  AEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR 123
            ED  +     P +LKVI E  AG    +KV  GTA+K+ TGA IPEGA+ V+  E  + 
Sbjct: 61  WEDIKEV----PAKLKVIGEYAAGTGENLKVEKGTAVKIFTGAPIPEGADTVVPVEYTET 116

Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183
           +   + V +    G NV  +GEDVKKGEV++ KG  +RP ++ ML ++    V V RKP 
Sbjct: 117 QDGYVIVKKSFKQGANVRRRGEDVKKGEVVIPKGKEIRPYEMGMLASVNRAVVSVYRKPH 176

Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243
           VGI+ TG E++ +  E+  +  +I  +N+  +   V +  G P   G+ PDE  K++E I
Sbjct: 177 VGILSTGDEIL-DVCEEQTKPSQIRTSNNYTVYGQVLQAGGIPHNLGIAPDEPQKLKE-I 234

Query: 244 KKAKRECDLVLVTGGSAFGDKDYAHRFVKLL-----FHGTTIKPGRPIGYG-----ERVF 293
            ++  + D+ + TGG + G+KDY    V+ L     FH   IKP +P+ +G     +  F
Sbjct: 235 MRSIHKYDIFITTGGVSMGEKDYVQYLVEDLGIDVKFHKLRIKPAKPVLFGVYGENKLFF 294

Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARD-YEVKLRAILEDDV-PSQLGRHEFV--KVLY 349
            + G PV+    F L V  A+  M G R+ ++ K+ AILE D       R EF   +V +
Sbjct: 295 GLPGNPVSAAVAFDLLVYPAIKAMQGHREVFKQKVTAILEGDYRRKNADRREFARCRVWF 354

Query: 350 RDGK--AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
            +G+   +   K+ S +++SLV SNAY+ V E     ++G+EV + L+
Sbjct: 355 ENGRYHCEPYPKQDSHMLTSLVNSNAYMVVYEGVNELKKGQEVEVILF 402


>sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0886
           >gi|2129131|pir||F64410 molybdenum cofactor biosynthesis
           protein moeA homolog - Methanococcus jannaschii
           >gi|1591564|gb|AAB98890.1| (U67532) molybdenum cofactor
           biosynthesis protein (moeA) [Methanococcus jannaschii]
           Length = 620
           
 Score =  237 bits (598), Expect = 2e-61
 Identities = 140/398 (35%), Positives = 236/398 (59%), Gaps = 27/398 (6%)

Query: 11  EALTLLLNDVTEIQ-DVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQ 69
           EA +++   + +++ +VE V L  A+ RVLA+D+ S  D+PP+DR+ +DGYAV+AEDT++
Sbjct: 12  EAKSIINESLKKLKNEVEEVDLFNAIGRVLAEDVFSNIDIPPYDRAKMDGYAVKAEDTYE 71

Query: 70  AREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIY 129
           A E +P+ELKVI  + AGE   +++ +G  +++ TGA IP+GANAV+M E  +R+ +++ 
Sbjct: 72  ADEDNPVELKVIGSLKAGEIKDLEINNGECVEIATGAIIPKGANAVVMVEYTERDNDRVK 131

Query: 130 VLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIIT 189
           + R V P +N+ F G D+  GE++LRK T L P+D+ +L A+G   V V +K + GII T
Sbjct: 132 IYRAVPPMENIQFTGSDIMAGELVLRKNTKLTPRDIGVLAAIGKSKVKVYKKLKFGIIST 191

Query: 190 GSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRE 249
           G+E++  P+E   E GKI + NS  L S +     +   +G+  D++++++E IKKA + 
Sbjct: 192 GNEII-SPNEQ-LEFGKIYDINSYTLVSYIKTLGYDFEFFGIAKDDKEELKEKIKKALK- 248

Query: 250 CDLVLVTGGSAFGDKDYAHRFV-----KLLFHGTTIKPGRPIGYG----ERVFIMSGYPV 300
           CD++L++GG++ G  D     +     K+L HG  IKPG+P   G    + +  + GYP 
Sbjct: 249 CDIILLSGGTSAGVGDLTETAIKELGGKILVHGIKIKPGKPTIIGKIDNKLIVGLPGYPT 308

Query: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVL---YRDGKAKVI 357
           +    F +             D +  ++A       S  GR E++ V+   +++G +   
Sbjct: 309 SCLTIFDVLF----------GDEKNVVKAKFPVRYISAKGRVEYLPVILVKHKNGFSAYP 358

Query: 358 KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
             KGSG I+SL E++ Y+ + E+ E     E+V + L+
Sbjct: 359 ITKGSGAITSLSEADGYIIIDENKE-ILENEDVEVHLF 395


>pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622104|gb|AAB85499.1| (AE000873) molybdenum
           cofactor biosynthesis protein MoeA [Methanobacterium
           thermoautotrophicum]
           Length = 409
           
 Score =  236 bits (595), Expect = 4e-61
 Identities = 138/381 (36%), Positives = 220/381 (57%), Gaps = 12/381 (3%)

Query: 24  QDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEE 83
           Q  E V + +A  RVLA DI S  D+PPFDR++ DGYAVRA DTF A E +P  L+ IE 
Sbjct: 29  QGTESVDILDADGRVLADDIESPVDLPPFDRASRDGYAVRAADTFGADEENPATLRCIET 88

Query: 84  VPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFK 143
           V AG  P ++V  G   ++ TGA +PEGA+AV+M E    E +++Y+ RP  P Q++A +
Sbjct: 89  VEAGSVPSLEVAEGLCTRISTGAPVPEGADAVVMVEYTWEEVDRVYIQRPAYPSQHIAAR 148

Query: 144 GEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFE 203
           G D++ G V+LR GT+L P  +A L A GI  V V  KP V +I TG+EL+E   +   E
Sbjct: 149 GSDIRAGNVLLRTGTVLSPDKIAALSAAGITRVNVISKPSVCVISTGNELIEPSGQ--LE 206

Query: 204 EGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGD 263
            GKI ++NS  L S + +        G++ D+  ++R+AI +   E D+V+ +GG++ G 
Sbjct: 207 PGKIFDSNSAGLSSALKEAGCSVKHGGIVRDDYGELRDAILRGLEEADMVITSGGTSAGA 266

Query: 264 KDYAHRFV----KLLFHGTTIKPGRPIGYG---ERVFI-MSGYPVAVFAQFHLFVKHALA 315
            D     +    +++ HG +IKPG+P   G   +++ + + G+PV+    F   ++  + 
Sbjct: 267 GDILSEVLDELGRVVIHGISIKPGKPTIVGVVDDKIVVGLPGFPVSALIVFMSLIEPFIR 326

Query: 316 KMVGARDYEVKLRAI-LEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVESNAY 374
           K+ G +     ++ + L + + S  GR  +  V+     A+ I  K SG +++L  ++ Y
Sbjct: 327 KLSGRKASSGHVKTLKLAERLHSSRGRVHYALVMVDGDYARPI-FKDSGAVAALAGADGY 385

Query: 375 LEVPEDSEGYRRGEEVWITLY 395
           +EVP++ E    GEEV + L+
Sbjct: 386 IEVPKNVEIINEGEEVEVVLF 406


>emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (moeA-2) related
           protein [Thermoplasma acidophilum]
           Length = 399
           
 Score =  226 bits (569), Expect = 5e-58
 Identities = 138/403 (34%), Positives = 221/403 (54%), Gaps = 26/403 (6%)

Query: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60
           MEFK L PY EA+ +       +++  +V + E++ R  ++D++S  D P  DRSAVDG 
Sbjct: 1   MEFKSLTPYGEAIRMASGLRINVRE-SYVSVAESVGRYCSRDVVSPVDFPEADRSAVDGI 59

Query: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120
           A+R ED+  A   +PI+L ++ EV  G+SP  ++  G    V TG+ IPEGANAV+M+E 
Sbjct: 60  ALRYEDSLSASRSNPIQLSLVGEVRIGDSPAFRINRGECAIVYTGSPIPEGANAVLMKED 119

Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180
                  + V R +   QN++  GED+K+G+ I+++G+ + P  L      GI  VPV  
Sbjct: 120 ASIGKSMVSVYRQMKKFQNISRAGEDLKRGDTIIKRGSRIMPWHLPAFIESGIDKVPV-M 178

Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240
              +GI+ TG+E+V          G +  +++ ML++++ +   +   YG + D+E +IR
Sbjct: 179 DAEIGIVSTGTEIV---------RGLVKNSSAPMLEAMISRMGLKSAFYGNVEDDESRIR 229

Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGY----GERV 292
             I+  K   D+++VTGGS    +D  H  +    +L+FHG  +KPGR  G     G+ V
Sbjct: 230 SVIEGMK--SDIIIVTGGSGPSSQDLVHDIIASNGQLIFHGVRMKPGRTTGLGMMDGKPV 287

Query: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKL-RAILEDDVPSQLGRHEFVKV--LY 349
           F++SG PVA    F   +  A+    G +  E +  R  L   + +      FV+V    
Sbjct: 288 FMISGLPVAALIAFENIIDPAIRSWFGMKSLERRTRRGYLTRSIFNNENMRMFVRVRMFE 347

Query: 350 RDGKAKV--IKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
            DGK  V  ++  GSG+I+S++ ++ YL + E+SEGY  G EV
Sbjct: 348 EDGKTMVEPMRTTGSGVINSVISADGYLVIEENSEGYPEGAEV 390


>dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus halodurans]
           Length = 423
           
 Score =  217 bits (548), Expect = 1e-55
 Identities = 138/407 (33%), Positives = 226/407 (54%), Gaps = 23/407 (5%)

Query: 7   MPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAED 66
           +P  EA+  ++    E + +E VPL+EA  R LAQ ++++ +VPPFD+S +DG+A+RA D
Sbjct: 8   IPVHEAVEQVVAFAKE-RAMEWVPLEEADGRFLAQPLVADHNVPPFDKSPLDGFAIRAVD 66

Query: 67  TFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGE 126
           T  A   +P+ LK+IEE+ AG+  +   + G AI+++TGA++PEG +AV+M E+ K   E
Sbjct: 67  TEDATRETPVRLKIIEEIGAGQVAQKVPSQGEAIRIMTGAQMPEGTDAVVMFELTKEISE 126

Query: 127 K----IYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182
                I V R   PG N++F GED K+G  ++ KG  +     A+L   G   VPV + P
Sbjct: 127 AGESFIEVKRSFQPGDNISFCGEDAKEGTPLVEKGRQIDAGIKALLATFGYAKVPVYKMP 186

Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242
           ++GI  TG+EL+E   ++    GKI  +N+ M+ S V +   EP+  G + D+ D+  +A
Sbjct: 187 KIGIFATGTELLE--VDEPLVPGKIRNSNAYMVASQVKQIGAEPVYLGKLVDDFDQCYDA 244

Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRF-----VKLLFHGTTIKPGRPIGYGER----VF 293
           I  A  + D+++ TGG + GD DY           +LF+   ++PG      ER    +F
Sbjct: 245 IATALADVDVLVTTGGVSVGDYDYLPAIYEKLGANVLFNKIAMRPGSVTTVAEREGQLLF 304

Query: 294 IMSGYPVAVFAQFHLFVKHAL-AKMVGARDYEVKLRAILEDDVPSQLGRHEFVK--VLYR 350
            +SG P A F  F L V+  +       + +  +++A L  D P       FV+  V ++
Sbjct: 305 GLSGNPSACFVGFELLVRPFIHVGFCSEQPFLKRVKATLGRDFPKPNPFTRFVRSQVEFK 364

Query: 351 DGKAKVIKKKG---SGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394
             +  ++K  G   SG+++SL  +N  L +P  + G++ G+EV + L
Sbjct: 365 IDRL-IVKPTGLDKSGVVTSLANANGLLMLPGGTRGFQAGDEVDVLL 410


>dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis protein [Clostridium
           perfringens]
           Length = 406
           
 Score =  216 bits (545), Expect = 3e-55
 Identities = 136/403 (33%), Positives = 226/403 (55%), Gaps = 19/403 (4%)

Query: 4   KKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVR 63
           KK +   EAL +L N  T+    E V + ++L RVL  D+ S+ + PPF++S  DGYA +
Sbjct: 2   KKFIALEEALEIL-NKNTKALKSEVVSIKDSLKRVLYGDVKSKINNPPFNKSVFDGYAFK 60

Query: 64  AEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR 123
           +ED+    + +PIELK+++E+ AG+  ++++  G AI+++TGA IP GA+ V+ QE  +R
Sbjct: 61  SEDSKGTSKENPIELKIVDEIFAGDFSEIEIKHGEAIRIMTGAPIPVGADCVLKQEETER 120

Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183
            G+ + + + +   +N++F GED+K GE +++KG  L   DL ++ + GI  V V +KP+
Sbjct: 121 HGDLVKIFKEMKANENISFMGEDIKIGETLIKKGKRLDYADLGIMASSGISEVLVYKKPK 180

Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243
           V II TG E+ +  S    + GKI ++N   L + + +     +    + D   KI EAI
Sbjct: 181 VSIISTGDEVCDINS--TLKPGKIYDSNLYSLSARIEELGYNVLSMEHVGDNILKIGEAI 238

Query: 244 KKAKRECDLVLVTGGSAFGDKDYAHRF-----VKLLFHGTTIKPGRPIGYGER----VFI 294
           +KA  + D+V  TGG++ G+KD   +       + LF    IKPG  +   +R    +  
Sbjct: 239 EKAFEKSDIVFTTGGASVGEKDLMQKVSGSIGFERLFWKIKIKPGSAVVCSKRQEKILIS 298

Query: 295 MSGYPVAVFAQFHLFVKHALAKMVGARD-YEVKL-RAILEDDVPSQLGRHEFVK--VLYR 350
           +SG P A    F L  K  L K+ G  +   +K  + +L D    +  +  F++  ++Y 
Sbjct: 299 LSGNPNAALTTFELLGKPVLKKLEGEEENINIKREKGVLMDSFNKKSPQRRFLRGNIIYD 358

Query: 351 DGKAKVI---KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
           +  AKV     K G+GI+SSL+ +N  +E+ + +EG  RGE V
Sbjct: 359 EKGAKVYITQIKSGNGILSSLLNANCLIEIEKGNEGLNRGEVV 401


>gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis protein; MoeA1
           [Halobacterium sp. NRC-1]
           Length = 407
           
 Score =  211 bits (531), Expect = 1e-53
 Identities = 145/404 (35%), Positives = 216/404 (52%), Gaps = 31/404 (7%)

Query: 3   FKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAV 62
           FK+     EA   LL+ V  +     V L +A  RVLA D+ +   VP ++R+A+DG+AV
Sbjct: 10  FKQRTRVAEARERLLSAVDPLARTARVALGDADGRVLAADVEAPRAVPHYERAAMDGFAV 69

Query: 63  RAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK 122
           RA DTF A + SP+ L    +V  G      V  G A++V TG+++P GA+AV+M E  +
Sbjct: 70  RAADTFGAGDRSPVVL----DVGTGS-----VGPGEAVRVHTGSELPAGADAVVMIEDAE 120

Query: 123 REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182
           R G+++ V    A G NVA  GEDV  G+ +   G  LRP DL +LK+ G+ +V V  +P
Sbjct: 121 RRGDRVDVFAAAAGGANVAPIGEDVSDGQHLYDAGHRLRPSDLGLLKSAGVDAVAVYERP 180

Query: 183 RVGIIITGSELV-EEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIRE 241
            VG++ TG ELV  +P       G++VETN   +   V ++ G P   GV+ D+E  +R 
Sbjct: 181 TVGVLPTGEELVAADPG-----PGEVVETNGGTVAQYVSRWGGVPTRRGVVTDDEAALRT 235

Query: 242 AIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGY----GERVF 293
           AI++A    D+V+ TGGS+ G +D+    +     +L HG  ++PG P+         V 
Sbjct: 236 AIREAVDSHDVVVTTGGSSVGARDHVPEVIADLGTVLVHGVALQPGHPVALCVVDDTPVV 295

Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVG--ARDYEVKLRAILEDDVPSQLGRHEFVKVLY-- 349
            + GYPVA       F++  L K VG           A+L   + S+ G   FV+V    
Sbjct: 296 ALPGYPVAAIVNAVQFLR-PLLKAVGHAPATAHPTTDAVLARKIASEPGTRSFVRVTRHG 354

Query: 350 -RDGKAKVIKKK--GSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
             DG+  V   +  GSG++SS+  ++ ++ VPED EGY  G  V
Sbjct: 355 DEDGRPTVTPTRAGGSGVLSSVALADGWVVVPEDCEGYDAGTTV 398


>gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus]
           Length = 419
           
 Score =  210 bits (530), Expect = 2e-53
 Identities = 131/409 (32%), Positives = 228/409 (55%), Gaps = 19/409 (4%)

Query: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60
           +E +  +P REA+  ++    E + V++VPL+++L  VLA+DI++ +++P F++S  DG+
Sbjct: 3   VEKRNPIPVREAIKRVVEQDIETE-VQNVPLNKSLGYVLAEDIVATYEIPRFNKSPYDGF 61

Query: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120
           A+R+EDT  A   + IE +VI+ + AG      V    A++++TGA++P GA+AV+M E 
Sbjct: 62  ALRSEDTVGASGDNRIEFEVIDHIGAGSVSDKTVGPNQAVRIMTGAEVPAGADAVVMLEQ 121

Query: 121 VKREGEKIYVLRPV-APGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVK 179
            K EG+  + +R   +  +NV+ KGE+ + G+V+L+KG  +    +A+L   G   VPV+
Sbjct: 122 TK-EGDHTFTIRKTFSHNENVSLKGEETEVGDVVLKKGQRINAGGIAVLATFGYTEVPVR 180

Query: 180 RKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKI 239
           + P   II TGSEL++    D  E GKI  +N  M++ L+++F  +  +Y +  D+ +  
Sbjct: 181 KLPSAAIIATGSELLD--VGDELEPGKIRNSNGPMIEGLLNQFGLDGEVYKIQEDDLESS 238

Query: 240 REAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGR----PIGYGE 290
              +K+A    D+V+ TGG + GD DY     K     +LF+   ++PG      + +G+
Sbjct: 239 IAVVKQAMETHDMVITTGGVSVGDFDYLPEIYKALDAEVLFNKVQMRPGSVTTVAVAHGK 298

Query: 291 RVFIMSGYPVAVFAQFHLFVKHALAKMVGARD-YEVKLRAILEDDVPSQLGRHEFV--KV 347
            +F +SG P A +  F LFVK  +  M+GA + +   ++A L +D         F+  K 
Sbjct: 299 YLFGLSGNPSACYTGFQLFVKTGVLNMMGANEKFPQVVKATLMEDFKKANPFTRFIRSKA 358

Query: 348 LYRDGKAKVIKK--KGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394
                +A V+      SG + ++  SNA + +P  + G+  G  V + L
Sbjct: 359 TLNGMEATVVPSGFNKSGAVVAIAHSNAMVMLPSGTRGFHAGNTVDVIL 407


>pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus subtilis
           >gi|2633799|emb|CAB13301.1| (Z99111) molybdopterin
           biosynthesis protein [Bacillus subtilis]
           >gi|3282112|gb|AAC24902.1| (AF012285) molybdopterin
           biosynthesis protein MoeA [Bacillus subtilis]
           Length = 430
           
 Score =  210 bits (529), Expect = 2e-53
 Identities = 135/388 (34%), Positives = 212/388 (53%), Gaps = 20/388 (5%)

Query: 25  DVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEV 84
           + E V L+++L+R LA+DI ++  VP FDRS  DG+AVRA DT +A   +P+  +VI+ +
Sbjct: 25  ETEWVALEDSLHRFLAEDITADHHVPAFDRSPYDGFAVRACDTAEASRENPVRFEVIDHI 84

Query: 85  PAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEK----IYVLRPVAPGQNV 140
            AG   + ++    A++++TGA+IPEGA+AV+M E+ +   E     + + R    G N+
Sbjct: 85  GAGAVSEKELGPFQAVRIMTGAQIPEGADAVVMIELTQAFEENGKSFMSLKRRFQTGDNI 144

Query: 141 AFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSED 200
           +  GED +KG V+L KGT + P   A+L   G  SVPV RKP VGII TG+EL+     D
Sbjct: 145 SKTGEDAQKGSVLLTKGTRVTPGVTALLATFGYASVPVVRKPVVGIIATGTELLN--VSD 202

Query: 201 AFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSA 260
             E GKI  +N+ M+ +   +    P+  G I DE DK   A+K+A ++ D ++ TGG +
Sbjct: 203 PLEPGKIRNSNASMVYAQAIEAGATPLYLGKISDELDKSFAAVKEAMKKVDFLITTGGVS 262

Query: 261 FGDKD-----YAHRFVKLLFHGTTIKPGRPIGYGER----VFIMSGYPVAVFAQFHLFVK 311
            GD D     Y      +LF+   ++PG            +F +SG P A +  F LFVK
Sbjct: 263 VGDFDFLPAIYEKLGADVLFNKVAMRPGSVTTVAHANDMLLFGLSGNPSACYVGFELFVK 322

Query: 312 HALAK-MVGARDYEVKLRAILEDDVPSQLGRHEFVKVL--YRDGK--AKVIKKKGSGIIS 366
             +   ++    + +   A+L  D P       FV+ L  +++GK  A  +    S  ++
Sbjct: 323 PIIQTWLLNETPHSICAEAVLTKDFPKPNPFTRFVRALVHHQEGKLLATPVGLDKSSSVT 382

Query: 367 SLVESNAYLEVPEDSEGYRRGEEVWITL 394
           SL ++NA++ +P  + GY  G  V + L
Sbjct: 383 SLADANAFIILPGGTRGYESGRTVQVLL 410


>emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (moeA-1) related
           protein [Thermoplasma acidophilum]
           Length = 626
           
 Score =  203 bits (511), Expect = 3e-51
 Identities = 118/398 (29%), Positives = 219/398 (54%), Gaps = 13/398 (3%)

Query: 3   FKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAV 62
           F +L+   +A +++  ++ ++  V  VP++EA+    A+DI S++DVPPFDRS VDG+AV
Sbjct: 4   FHRLVSAEDARSIMAGEMRKLMRVVEVPIEEAVGLTAAEDIFSQYDVPPFDRSEVDGFAV 63

Query: 63  RAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK 122
              D   A+E +P+ L++   +  GE+  + V  G A+ + TG+ +P+G++AV+M E  +
Sbjct: 64  DHADVDGAQEDAPVTLRIAGSISPGETGNVTVERGKAVYIATGSVMPKGSDAVVMVEDTR 123

Query: 123 REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182
           + G+ + + R V PG+NVAF G D+  G++I + GT+L P+ LA L A G+  V V  + 
Sbjct: 124 QHGDYVDIYRSVYPGENVAFAGTDISLGDIIAKAGTVLTPEKLATLAASGVARVRVFDRI 183

Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFG-EPILYGVIPDEEDKIRE 241
           R+GI  TG+E+V   +    + G+I + N    ++ +    G   +  G +PD ED + +
Sbjct: 184 RIGIFSTGNEIVRPGTN--LKLGQIFDVNGYYFQTKLSSSGGVHAVFLGSVPDREDDMVK 241

Query: 242 AIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRPIGY---GERVF 293
            I+      D+++ +G ++ G  D  +R ++     +LFHG  ++PG+P  +   GE++F
Sbjct: 242 IIRDNLDSFDILMASGSTSAGFLDMLYRVIEKVGGSILFHGINMRPGKPTFFGRIGEKLF 301

Query: 294 I-MSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352
           I M G+P++     +  V  ++ K +       ++  +     P  +    +  ++ R+G
Sbjct: 302 IGMPGFPLSSAVILNYIVIPSIRKAISGDFERPRVVKVPVKIAPDHMQETVYPAIITRNG 361

Query: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
            A  I    SG IS +  ++ ++ +P D +    G+ V
Sbjct: 362 YAFPI-MGNSGSISRIRFADGFIAIPGDLKYVDPGDNV 398


>sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1075033|pir||B64124
           molybdopterin biosynthesis protein moeA - Haemophilus
           influenzae (strain Rd KW20) >gi|1574287|gb|AAC23098.1|
           (U32823) molybdopterin biosynthesis protein (moeA)
           [Haemophilus influenzae Rd]
           Length = 404
           
 Score =  200 bits (503), Expect = 3e-50
 Identities = 135/398 (33%), Positives = 214/398 (52%), Gaps = 23/398 (5%)

Query: 11  EALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQA 70
           +A + +L  +      E++ L EA NR+ A+DIIS  +VP FD SA+DGYAVR  D  Q+
Sbjct: 6   QARSKMLEQLPFPTQTEYLNLQEAANRICAEDIISPINVPSFDNSAMDGYAVRLSDLQQS 65

Query: 71  REYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-REGEKIY 129
                + L V  +  AG   + +  S +A++++TGA IPEG +AVIMQE V   E   I 
Sbjct: 66  -----LTLSVAGKSFAGNPFQEEWPSKSAVRIMTGAMIPEGTDAVIMQEQVTLNEDGTIT 120

Query: 130 VLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIIT 189
                 P QN+   GEDVKKG+V+L +G  L P  L +L +LGI  V   R+ +VG++ T
Sbjct: 121 FSELPKPNQNIRRIGEDVKKGDVVLEQGAQLTPVSLPLLASLGIAEVKCYRQLKVGVLST 180

Query: 190 GSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRE 249
           G ELVE       + G+I +TN   +K L+ K   E I  G++PD E +  +A   A+ +
Sbjct: 181 GDELVEVGK--PLQSGQIYDTNRFTVKLLLEKLHCEVIDLGLLPDNEAEFEKAFIAAQSQ 238

Query: 250 CDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYG--ERVFI--MSGYPVA 301
            DLV+ +GG + G+ D+    ++ +    F    IKPG+P  +G  E  +   + G PV+
Sbjct: 239 ADLVITSGGVSVGEADFTKAVLEKVGQVNFWKIAIKPGKPFAFGKLENAWFCGLPGNPVS 298

Query: 302 VFAQFHLFVKHALAKMVGARDYE--VKLRAILEDDVPSQLGRHEFVKVLY---RDGKAKV 356
               F+  V+  +AK+ G + ++      AI   ++   +GR +F +  Y     G+ +V
Sbjct: 299 ALVTFYQLVQPLIAKLQGQKQWKKPPHFSAIATMNLKKAVGRLDFQRGFYYINEQGQIEV 358

Query: 357 --IKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWI 392
             +  +GS + S+ V+SN ++ + ++      GE V I
Sbjct: 359 QSVGFQGSHLFSAFVKSNCFIVLEQERGNVSAGETVTI 396


>pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9656032|gb|AAF94681.1| (AE004231) molybdopterin
           biosynthesis MoeA protein [Vibrio cholerae]
           Length = 606
           
 Score =  192 bits (484), Expect = 4e-48
 Identities = 125/392 (31%), Positives = 212/392 (53%), Gaps = 23/392 (5%)

Query: 16  LLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSP 75
           +L+ ++ + + E V + E   RVLA+++ S  +VP +  SA+DGYA+R++D  +   Y  
Sbjct: 216 ILSLISPLAETESVAIQECYQRVLAREVFSPNNVPAYRNSAMDGYALRSDD-LERDSY-- 272

Query: 76  IELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKI-YVLRPV 134
              +V+ EV AG      V  G A+K++TGA +P GA+ V+M+E   + GE + +    +
Sbjct: 273 ---RVVAEVLAGSHYPKTVERGEAVKIMTGAPMPLGADTVVMREQATQNGELVSFAGAKI 329

Query: 135 APGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELV 194
             GQNV   GED+ +G+ +   G  +   ++ ML +LG       R  +V I  TG E V
Sbjct: 330 KAGQNVRQAGEDLAQGQAVFSIGQRVLSPEMGMLASLGFAHADAFRSLKVAIFSTGDE-V 388

Query: 195 EEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVL 254
           + P  D  E   I ++N   L  L+ +   + I  G+I D+E K+ + +++A ++ D+V+
Sbjct: 389 QAPGGD-IEPNSIFDSNRFTLTGLLKQLGCQVIDLGIIEDDEAKMMQVLEQAAKQADVVI 447

Query: 255 VTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQF 306
            +GG + GD D+    ++ L    F    ++PGRP+ +G+      F + G PVAV   F
Sbjct: 448 TSGGVSVGDADFIKSALEKLGQIDFWRINMRPGRPLAFGQIAGKPFFGLPGNPVAVMVSF 507

Query: 307 HLFVKHALAKMVGARDYE-VKLRAILEDDVPSQLGRHEFVKVLYRDG-----KAKVIKKK 360
             FV+ AL KM G + ++ +K+ AI  +D+ S+ GR EF + +Y          +   K+
Sbjct: 508 INFVEPALRKMQGEQGWQPLKVNAIALEDLRSRQGRTEFSRGVYAFNTQGQLTVRTTGKQ 567

Query: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWI 392
           GSGI+ S+ E+N  +E+    +  + GE V I
Sbjct: 568 GSGILRSMSEANCLIEIAPAIDTVKVGESVTI 599


>sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1002858|gb|AAC44505.1|
           (U34309) moeA gene product [Anabaena sp.]
           Length = 436
           
 Score =  192 bits (483), Expect = 6e-48
 Identities = 133/419 (31%), Positives = 213/419 (50%), Gaps = 34/419 (8%)

Query: 4   KKLMPY------REALTLLLNDVTEI---QDVEHVPLDEALNRVLAQDIISEFDVPPFDR 54
           K L PY      R+   ++ N V ++   QD E V L  A  R+LA  + S  D P +D 
Sbjct: 17  KPLHPYTPMPSVRDTANIIFNLVPKLDSQQDTEIVDLWAANGRILATPVNSTLDFPHWDN 76

Query: 55  SAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANA 114
           SA+DGYAVR ED   +    P+ L+V+ E+PAG  PK  +  G A ++ TGA +P G + 
Sbjct: 77  SAMDGYAVRYEDVHNSNAEQPVSLEVVAEIPAGYQPKFTLQPGQAARIFTGAVMPSGGDT 136

Query: 115 VIMQEMVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIK 174
           V+MQE  ++E  ++++L    PG+ V  K    + G  +L   T L   ++A+L A    
Sbjct: 137 VVMQEKTRQENNRVFILTTPKPGEFVRLKAAYYQAGTQLLPANTQLNAAEIAILAASQCP 196

Query: 175 SVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPD 234
            V V R+PRV I  TG ELV    +   + G+IV++N   L +LV +   EPIL+G++ D
Sbjct: 197 QVKVYRRPRVAIFSTGDELV--TLDQPLQPGQIVDSNQYALAALVKQNGAEPILFGIVKD 254

Query: 235 EEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFV-----KLLFHGTTIKPGRPIGYG 289
               + E I KA    D+V+ +GG + GD DY  + +     K+      ++PG+P+   
Sbjct: 255 NPTALGETISKAIANADIVISSGGVSVGDYDYVDQILASLGAKIHIRSVEMRPGKPLTVA 314

Query: 290 ------ERVFI-MSGYPVAVFAQFHLFVKHALAKMVG-ARDYE---VKLRAILEDDVPSQ 338
                   +++ + G P AV   F  FV+  + K+ G A+ +E   VK+R+   D++ S 
Sbjct: 315 TFPTPPAPIYLGLPGNPAAVLVTFWRFVQPVIRKLGGLAKGWEPVFVKVRS--HDELHSD 372

Query: 339 LGRHEFV--KVLYRDGKAKVIKKKG---SGIISSLVESNAYLEVPEDSEGYRRGEEVWI 392
             R  ++   +   DG  +  K  G   SG + +L ++NA   +P        G++V +
Sbjct: 373 GKRETYIWGSLHLVDGLYEFHKAGGSHSSGNLINLAQTNALAVLPLGETFISSGKDVLV 431


>pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9658029|gb|AAF96518.1| (AE004391) molybdopterin
           biosynthesis MoeA protein [Vibrio cholerae]
           Length = 435
           
 Score =  186 bits (467), Expect = 4e-46
 Identities = 126/406 (31%), Positives = 208/406 (51%), Gaps = 24/406 (5%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           LMP  +AL  +L+ +  +Q    +PL EAL  VLA+ I+S   VPPFD SA+DGYAVR  
Sbjct: 33  LMPIEDALKKMLSRIQPVQTTLRLPLPEALGYVLAEAILSPIHVPPFDNSAMDGYAVRRA 92

Query: 66  DTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM--VKR 123
           +  Q +      L V  +  AG+         T ++++TGA+IP G +AVIMQE   +  
Sbjct: 93  ELAQQK-----PLPVAGKSFAGQPFTADWPPMTCVRIMTGAQIPAGCDAVIMQEQATITE 147

Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183
           EG  ++    V    N+   G+D+++ +V+L +G  L  +D+ M+  LGI  V V RKP+
Sbjct: 148 EG-VVFCQHEVKLNDNIRPTGDDIRQNDVVLERGARLTARDIPMIATLGISHVTVYRKPK 206

Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243
           V    TG EL  +P  +  + G+I ++N   +K L+  F  E I  G++PD    ++   
Sbjct: 207 VAFFSTGDEL--KPLGEPLQAGQIYDSNRYGIKPLIENFGCEAIDLGIVPDCPATLKATF 264

Query: 244 KKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYG---ERVFI-M 295
           ++A+   D+V+ +GG + G+ DY    ++ L    F    IKPG+P  +G   +  F  +
Sbjct: 265 EQAQSLADVVVTSGGVSVGEADYTKDILEELGEIGFWKLAIKPGKPFAFGALQDAWFCGL 324

Query: 296 SGYPVAVFAQFHLFVKHALAKMVGARDYEV--KLRAILEDDVPSQLGRHEFVKVLYRDGK 353
            G PV+     ++ V+  LAK+ G   ++    + AI         GR +F + +YR   
Sbjct: 325 PGNPVSAVLTMYVLVQPMLAKLAGHSAWQAPESIPAITRSPFKKAPGRTDFQRGIYRIEN 384

Query: 354 AKVIKK----KGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
            + + +    + SG   S+  +N ++ +  +      GE V I L+
Sbjct: 385 GQFVVESTGNQSSGAFRSMSLANCFVVLERERGRVEVGETVQIQLF 430


>sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|78705|pir||A32352
           molybdopterin biosynthesis protein moeA - Escherichia
           coli >gi|145539|gb|AAA23579.1| (M21151) chlE protein
           [Escherichia coli] >gi|1651376|dbj|BAA35515.1| (D90720)
           Molybdopterin biosynthesis MoeA protein. [Escherichia
           coli] >gi|1651379|dbj|BAA35522.1| (D90721) Molybdopterin
           biosynthesis MoeA protein. [Escherichia coli]
           >gi|1787049|gb|AAC73914.1| (AE000185) molybdopterin
           biosynthesis [Escherichia coli K12]
           Length = 411
           
 Score =  185 bits (464), Expect = 1e-45
 Identities = 134/406 (33%), Positives = 206/406 (50%), Gaps = 23/406 (5%)

Query: 1   MEFKK-LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDG 59
           MEF   LM    AL  +L+ VT +   E +PL +   R+LA D++S  DVP FD SA+DG
Sbjct: 1   MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDG 60

Query: 60  YAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQE 119
           YAVR  D    +      L V  +  AG+    +  +GT I+++TGA +PEG  AV+MQE
Sbjct: 61  YAVRLADIASGQP-----LPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQE 115

Query: 120 MVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVK 179
             ++    +     V  GQN+  +GED+  G V+   GT L   +L ++ +LGI  VPV 
Sbjct: 116 QTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVI 175

Query: 180 RKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKI 239
           RK RV +  TG EL + P +    +G+I +TN + +  ++ +   E I  G+I D+   +
Sbjct: 176 RKVRVALFSTGDEL-QLPGQ-PLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHAL 233

Query: 240 REAIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGYGER---- 291
           R A  +A  + D+V+ +GG + G+ DY    +    ++ F    IKPG+P  +G+     
Sbjct: 234 RAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSW 293

Query: 292 VFIMSGYPVAVFAQFHLFVKHALAKMVG--ARDYEVKLRAILEDDVPSQLGRHEFVK-VL 348
              + G PV+    F+  V+  LAK+ G  A     + R      +    GR +F + VL
Sbjct: 294 FCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVL 353

Query: 349 YR--DGKAKVIK--KKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
            R  DG+ +V     +GS I SS    N ++ +  D      GE V
Sbjct: 354 QRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWV 399


>emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri]
           Length = 408
           
 Score =  182 bits (456), Expect = 8e-45
 Identities = 109/296 (36%), Positives = 165/296 (54%), Gaps = 13/296 (4%)

Query: 33  EALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKM 92
           E   RVLA+D+ +E   PPF RSA+DGYAVR+ED           LKV+ E   GE   +
Sbjct: 42  ELSGRVLAEDVRAERPSPPFTRSAMDGYAVRSEDAEPGAR-----LKVVGESRIGEGTDV 96

Query: 93  KVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEV 152
           KV  G A+ V TGA +PEGA+AVI  E V+R+G++I V   V PG N+   G  V++GEV
Sbjct: 97  KVGPGEAVYVDTGAPVPEGADAVIPVEFVERDGDEIIVEEGVDPGDNLDPAGCYVEEGEV 156

Query: 153 ILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNS 212
           + R G ++ P D+ ++   G++ V V R  RV I++TG+ELV  PSE   E   +     
Sbjct: 157 LYRSGHLVEPVDVGVMLEHGVEEVDVHRPLRVSIVVTGNELVHRPSELESETQVVDCIGP 216

Query: 213 IMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK 272
           ++   L +    E +   ++ D+  +IRE ++      D+VL+TGGS+ G++D+    + 
Sbjct: 217 VLTAELENMGCVEVVGTSLVKDDPGEIRETVEDYADRSDVVLITGGSSVGERDHVKDILD 276

Query: 273 LLF----HGTTIKPGRPIGYGER----VFIMSGYPVAVFAQFHLFVKHALAKMVGA 320
             F    HG   +PGRP G   R     F + G+P + ++ F ++V  +L  + GA
Sbjct: 277 DTFDAFIHGIRARPGRPFGIAAREGTVAFTLPGWPTSCYSTFRVWVVPSLLVLAGA 332


>emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [Streptomyces
           coelicolor A3(2)]
           Length = 424
           
 Score =  180 bits (452), Expect = 2e-44
 Identities = 121/401 (30%), Positives = 197/401 (48%), Gaps = 41/401 (10%)

Query: 33  EALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKM 92
           +A   VL  DI     +PPFD S++DGYAVR  D   A E  P  L+V+ +V AG++  +
Sbjct: 24  DAQGCVLVDDITVPLSLPPFDNSSMDGYAVRVTDVAGASEEFPAVLEVVGDVAAGQTDPI 83

Query: 93  KVTSGTAIKVLTGAKIPEGANAVIMQE-----------------MVKREGEK--IYVLRP 133
            V  G A +++TGA +P GA AV+  E                  +  EG +  + V RP
Sbjct: 84  AVGPGQAARIMTGAPLPPGAEAVVPVEWTDGGSGEGPVAGMRARSLAPEGAEGHVQVYRP 143

Query: 134 VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSEL 193
                +V  KG DV+ G+  L  GT+L P  + +L A+G  +V V+ +PRV ++ TGSEL
Sbjct: 144 AEERAHVRAKGSDVRSGDRALAAGTVLGPPQIGLLAAIGRGTVRVRPRPRVVVLSTGSEL 203

Query: 194 VEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLV 253
           V+   ++    G+I ++NS  L +            G + D+ + +R  I+      DL+
Sbjct: 204 VQ--PDEQLAPGQIYDSNSFALTAAARDAGAIAYRVGAVADDAETLRATIEDQLVRADLM 261

Query: 254 LVTGGSAFGDKDYAHRFVKLL-----------FHGTTIKPGRPIGYGE------RVFIMS 296
           + TGG + G  D     +  +           F    ++PG+P G+G        +  + 
Sbjct: 262 VTTGGVSVGAYDVVKEALAHVGDEDEPGGGVDFRKLAMQPGKPQGFGSVGPDHTPLLALP 321

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARD-YEVKLRAILEDD--VPSQLGRHEFVKVLYRDGK 353
           G PV+ +  F LFV+ A+  ++G  D +   + A L  D  + S  GR +F++  +  G 
Sbjct: 322 GNPVSSYVSFELFVRPAIRTLMGLPDVHRPTVTASLAADKALTSPKGRRQFLRGSHAGGS 381

Query: 354 AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394
              +   GS ++++L ++NA + VPED+E    G EV + L
Sbjct: 382 VTPVGGSGSHLVAALAQANALIVVPEDTESVEPGTEVEVVL 422


>pir||G70829 probable molybdenum cofactor biosynthesis protein - Mycobacterium
           tuberculosis (strain H37RV) >gi|2909513|emb|CAA17395.1|
           (AL021932) moaA3 [Mycobacterium tuberculosis]
           Length = 405
           
 Score =  177 bits (445), Expect = 2e-43
 Identities = 113/369 (30%), Positives = 180/369 (48%), Gaps = 19/369 (5%)

Query: 29  VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88
           VPL +A   VL  D+++   +P FD SA+DGYAVRAEDT  A   +P+ L V E++PAG 
Sbjct: 23  VPLTQAQGLVLGGDVVAPLSLPVFDNSAMDGYAVRAEDTSGATPQNPVMLPVAEDIPAGR 82

Query: 89  SPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGEDVK 148
           +  + +   TA +++TGA +P GA A++  E      + + + +   PG+++   GEDV 
Sbjct: 83  ADMLTLQPVTAHRIMTGAPVPTGATAIVPVEATDGGVDSVAIRQQATPGKHIRRSGEDVA 142

Query: 149 KGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIV 208
            G  +L  G I+ P  L +  ALG+  +PV  + RV +I TGSEL    +    + G+I 
Sbjct: 143 AGTTVLHNGQIVTPAVLGLAAALGLAELPVLPRQRVLVISTGSELASPGT--PLQPGQIY 200

Query: 209 ETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGG---------- 258
           E+NSIML + V       +      D+  +    + +   + DL++ +GG          
Sbjct: 201 ESNSIMLAAAVRDAGAAVVATATAGDDVAQFGAILDRYAVDADLIITSGGVSAGAYEVVK 260

Query: 259 SAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQFHLFVKHAL 314
            AFG  DY      + F    ++PG P G G      +  + G PV+    F +F++  L
Sbjct: 261 DAFGSADYRGGDHGVEFVKVAMQPGMPQGVGRVAGTPIVTLPGNPVSALVSFEVFIRPPL 320

Query: 315 AKMVGARD-YEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIK--KKGSGIISSLVES 371
              +G  D Y     A+L   + S  G+ +F + +       VI      S  +  L  +
Sbjct: 321 RMAMGLPDPYRPHRSAVLTASLTSPRGKRQFRRAILDHQAGTVISYGPPASHHLRWLASA 380

Query: 372 NAYLEVPED 380
           N  L++PED
Sbjct: 381 NGLLDIPED 389


>gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis protein; MoeA2
           [Halobacterium sp. NRC-1]
           Length = 571
           
 Score =  176 bits (443), Expect = 3e-43
 Identities = 121/354 (34%), Positives = 180/354 (50%), Gaps = 15/354 (4%)

Query: 57  VDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVI 116
           +DGYAVRA DTF A E  P  L V   V AGE P ++VT+G A+ V TGA +P GA+AV+
Sbjct: 1   MDGYAVRAADTFGASEADPARLSVAGTVHAGEEPAVEVTAGRAVVVSTGAVMPPGADAVV 60

Query: 117 MQEMVKRE--GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIK 174
             E       G+ + V   VAPG  V   G D+  G   +  GT L  +++ +L ALG+ 
Sbjct: 61  KVEATTEADGGDAVDVRTSVAPGTAVMLAGADIAAGSRAIGPGTKLTAREIGVLSALGVG 120

Query: 175 SVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPD 234
           SV V+  P VGII TG ELV          G+I + NS  + + V    GEP++Y    D
Sbjct: 121 SVRVRGAPTVGIISTGDELVRPGDPLDSAAGQIHDVNSHTIAAAVEAAGGEPVVYPHAGD 180

Query: 235 EEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYGE 290
           +  ++   + ++  +CDLVL +G ++    D  +R  +    LL HG  +KPG+P+  GE
Sbjct: 181 DYAEMERLLVESAADCDLVLSSGSTSASAVDVIYRVAEERGDLLLHGVAVKPGKPMLVGE 240

Query: 291 ---RVFI-MSGYPVAVFAQFHLFVKHALAKMVGARDYE-VKLRAILEDDVPSQLGRHEFV 345
                ++ + GYPV+    F +FV   + +  G    E   +   +     S  GR   +
Sbjct: 241 IEGTAYVGLPGYPVSALTIFRVFVAPVVREAAGRGQPEPTVVTGEMARQERSAEGRRRLL 300

Query: 346 KV-LYRDGKAKVI---KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
            V L  DG    +     KGSG  +SLV+++  + VP D+     G+ V + L+
Sbjct: 301 PVGLVEDGAGDRLVYPVDKGSGATTSLVDADGTVTVPADTAYVAAGDSVDVALF 354


>pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9949132|gb|AAG06416.1|AE004728_2 (AE004728)
           molybdenum cofactor biosynthesis protein A2 [Pseudomonas
           aeruginosa]
           Length = 405
           
 Score =  174 bits (437), Expect = 1e-42
 Identities = 122/391 (31%), Positives = 208/391 (52%), Gaps = 32/391 (8%)

Query: 6   LMPYREALTLLLNDV--TEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVR 63
           LMP   AL  LL     T I   E VPL++A  RVLA D+++  D+PP+  SA+DGYA+R
Sbjct: 10  LMPVETALERLLELAAQTPIDTCEQVPLEQAGGRVLAVDLLAGLDLPPWPNSAMDGYALR 69

Query: 64  AEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR 123
             D      ++   L V +++ AG++PK  + +GT  ++ TGA +PEGA+ V MQE  + 
Sbjct: 70  LAD------WNGEPLPVSQKIFAGQAPK-PLQAGTCARIFTGAPLPEGADLVEMQENAEA 122

Query: 124 -EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182
            +  ++   +P+  GQ+V  +G+++++G+++L  GT LR  +L +  +LG  ++ V+RKP
Sbjct: 123 LDDGRVRFTQPLRVGQHVRPRGQEIRQGDLVLPAGTRLRSIELGLAASLGYAALEVRRKP 182

Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242
           RV ++ TG ELVE  +    + G+I  +N  +LK  + +   + +  G++PD+  + RE 
Sbjct: 183 RVALLSTGDELVE--AGQPLQAGQIYNSNRPLLKDWLQRLGCDVLDAGILPDDLARTRER 240

Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYGE----RVFI 294
           +       DL+L TGG + G+ D+    ++    L      IKPG+P+  G+     V  
Sbjct: 241 L-AGLAGVDLILSTGGVSVGEADFLGMALREAGELTLWKLAIKPGKPLTVGQFQGIPVIG 299

Query: 295 MSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLG------RHEFVKVL 348
           + G P +    F L  +  L + +G     V   A L  +VP+         R E+++  
Sbjct: 300 LPGNPASTLVTFALLARPYLLRRLG-----VAQVAPLRVEVPAGFAWTKAGQRREYLRGR 354

Query: 349 YRDGKAKVIKKKGSGIISSLVESNAYLEVPE 379
              G+A +   + SG++ S   +   +EV E
Sbjct: 355 LEQGRAVLYPNQSSGVLRSASWAEGLVEVRE 385


>pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968943|emb|CAB73939.1| (AL139078) putative
           molybdopterin biosynthesis protein [Campylobacter
           jejuni]
           Length = 396
           
 Score =  173 bits (434), Expect = 3e-42
 Identities = 114/391 (29%), Positives = 206/391 (52%), Gaps = 24/391 (6%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           LM Y E+L +L + +   + +E + L E L R+LAQDI +  + P F  SA+DGYA++ E
Sbjct: 2   LMSYEESLKILHSHIKTYEKIEKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFE 61

Query: 66  DTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREG 125
           D  +        LK++   PAG  P+  V +GT +K  TG+ + EG++ ++  E ++ E 
Sbjct: 62  DQDKP-------LKILGLTPAGTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENIRIEN 114

Query: 126 EKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVG 185
             +++ + V     V   GE+ KK E++L+KGT L   ++A+L  LG   + V  KP VG
Sbjct: 115 NTLFIEKKVPQAFAVRAVGENYKKDEILLKKGTRLNYSEIALLAELGFFHISVFIKPIVG 174

Query: 186 IIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKK 245
           ++ +GSE +++  E      +I  +N I + +L      +  ++ ++ D+E      ++ 
Sbjct: 175 VLSSGSE-IKDLGEALENPAQIRSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLES 233

Query: 246 AKRECDLVLVTGGSAFGDKDYAHRFVK---LLFHGTTIKPGRPIGYGER----VFIMSGY 298
           A + CD+++ TGG + GD D+  + +K   ++     IKPGR I   +     +  + G+
Sbjct: 234 ALQSCDILVTTGGVSMGDFDFLKKAIKEYEIIIDKADIKPGRHIKIAKANEKFIIALPGF 293

Query: 299 PVAVFAQFHLFVKHAL-AKMVGARDYEVKLRAILEDDVPSQLGRHEFV--KVLYRDGKAK 355
           P +    F+L+ +  L + ++  +DY  K  A L+     +    EFV   + +++G+  
Sbjct: 294 PYSAMVMFNLYTREILNSWLLQPKDYICK--AFLQGSYKKKTPYLEFVACNIEFKNGRIL 351

Query: 356 VI---KKKG-SGIISSLVESNAYLEVPEDSE 382
                KK+G S II++L    A + VP++ E
Sbjct: 352 ANLEGKKEGSSAIINNLNNKAALMVVPKECE 382


>sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1256834|gb|AAA96529.1|
           (U53178) moeA gene product [Salmonella typhimurium]
           Length = 412
           
 Score =  168 bits (422), Expect = 8e-41
 Identities = 133/407 (32%), Positives = 201/407 (48%), Gaps = 26/407 (6%)

Query: 1   MEFKK-LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDG 59
           MEF   LMP   ALT +L+ +T +  VE +PL     R+LA DI+S  DVP FD SA+DG
Sbjct: 3   MEFSAGLMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDG 62

Query: 60  YAVRAEDTFQAREYSPIELKVIEEVP-AGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQ 118
           YAVR  D   A +  P+  K     P  GE P     +GT I+++TGA +P G  AV+MQ
Sbjct: 63  YAVRVAD-LSADKPLPVAGKAFAGQPYQGEWP-----AGTCIRIMTGAPVPAGCEAVVMQ 116

Query: 119 EMVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPV 178
           E  ++  +       V  GQN+  +GED+++  V+   GT L   +L +L +LGI    V
Sbjct: 117 EQTEQTDDGERFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAELPVLASLGIADAQV 176

Query: 179 KRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKF-FGEPILYGVIPDEED 237
            RK RV +  TG EL + P +   E  +I +TN + +  ++ +  + E I  G+IPD+  
Sbjct: 177 VRKVRVALFSTGDEL-QLPGQ-PLEADQIYDTNRLTIHLMLQQLGWREVINLGIIPDDPG 234

Query: 238 KIREAIKKAKRECDLVL---VTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGER--- 291
           K+R  I  A  + D+V+   V+ G A   K       ++ F    IKPG+P  +G+    
Sbjct: 235 KLRGFI-DADSQADVVISSRVSEGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNS 293

Query: 292 -VFIMSGYPVAVFAQFHLFVKHALAKMVG--ARDYEVKLRAILEDDVPSQLGRHEFVK-V 347
               + G PV+    F+  V+  LAK+ G  A     + R      +    GR +F + +
Sbjct: 294 WFCGLPGNPVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVRTASRLKKTPGRLDFQRGI 353

Query: 348 LYRDGKAKV----IKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
           L R    ++       +GS I SS    N ++ +  +      GE V
Sbjct: 354 LQRSANGELEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWV 400


>gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulfolobus
           solfataricus]
           Length = 550
           
 Score =  167 bits (418), Expect = 2e-40
 Identities = 113/334 (33%), Positives = 180/334 (53%), Gaps = 19/334 (5%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           L    EA+ + L+ +  I     V + ++   V A+D+ S  D PPF RS VDGYA+++ 
Sbjct: 14  LYSIEEAIRVYLSSLNFIPKTVEVEVKDSFGYVSAEDLNSPIDYPPFSRSNVDGYALKSS 73

Query: 66  DTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR-E 124
            T       P ELKVI+ +  GE  ++ +    A++V TGA IP GA+AVI  E VK   
Sbjct: 74  CT-------PGELKVIDRIEIGEFKEVHINECVAVEVDTGAIIPMGADAVIKVEDVKIIS 126

Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184
           G  I V + +  GQN+ + G D+ K  +ILRKG ++  + + +L +LGI  V V  K +V
Sbjct: 127 GNLIKVDKKMTFGQNIGWIGSDIPKNSIILRKGEVISHEKIGLLASLGISKVKVYEKLKV 186

Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244
            +I TG ELVE    ++   GKI E+N   L S + + + + +   ++ D+ + I+  IK
Sbjct: 187 YLIATGDELVE--PGNSLSPGKIYESNLHYLYSKLKQNY-QIVGLSLLRDDIESIKNEIK 243

Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYG----ERVFIMS 296
           +A    D++++TGG++ G+KD+ HR +K    ++ HG  IKPG+P   G    + V  + 
Sbjct: 244 RAISLADVLILTGGTSAGEKDFVHRAIKELGSIIVHGIKIKPGKPTILGVVDNKPVIGLP 303

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI 330
           G  V+    F   +   L  +  +R   V+L  I
Sbjct: 304 GNIVSSVVVFDTVISEILRNLYPSRKEIVELGKI 337


>sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN LINKER PROTEIN)
           >gi|111656|pir||JH0681 gephyrin - rat
           >gi|56312|emb|CAA47009.1| (X66366) Gephyrin [Rattus
           norvegicus]
           Length = 736
           
 Score =  164 bits (411), Expect = 2e-39
 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%)

Query: 19  DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78
           ++T +   E +   + + RVLAQD+ ++ ++PPF  S  DGYAVRA D        P + 
Sbjct: 335 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 387

Query: 79  KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130
            +I E  AGE P   V  G  ++V TGA IP GA+AV+  E  +  RE +      ++ +
Sbjct: 388 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 447

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
           L    PGQ++   G D+K+GE +L KGT + P ++ +L  +G+  V V + P V ++ TG
Sbjct: 448 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 507

Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250
           +EL+    ED    GKI ++N   L + + +     I  G++ D  D +  A+ +     
Sbjct: 508 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 565

Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296
           D+++ +GG + G+KDY  + + +  H         +KPG P         G  + +F + 
Sbjct: 566 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 625

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353
           G PV+     +LFV  AL KM G  D     +K R   +  +  +   H  +   +    
Sbjct: 626 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 685

Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390
               +  G+ + S L+    +N  L +P  +E Y    +GE V
Sbjct: 686 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 728


>dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens]
           Length = 768
           
 Score =  164 bits (411), Expect = 2e-39
 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%)

Query: 19  DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78
           ++T +   E +   + + RVLAQD+ ++ ++PPF  S  DGYAVRA D        P + 
Sbjct: 367 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 419

Query: 79  KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130
            +I E  AGE P   V  G  ++V TGA IP GA+AV+  E  +  RE +      ++ +
Sbjct: 420 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 479

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
           L    PGQ++   G D+K+GE +L KGT + P ++ +L  +G+  V V + P V ++ TG
Sbjct: 480 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 539

Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250
           +EL+    ED    GKI ++N   L + + +     I  G++ D  D +  A+ +     
Sbjct: 540 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 597

Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296
           D+++ +GG + G+KDY  + + +  H         +KPG P         G  + +F + 
Sbjct: 598 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 657

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353
           G PV+     +LFV  AL KM G  D     +K R   +  +  +   H  +   +    
Sbjct: 658 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 717

Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390
               +  G+ + S L+    +N  L +P  +E Y    +GE V
Sbjct: 718 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 760


>gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens]
           Length = 736
           
 Score =  164 bits (411), Expect = 2e-39
 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%)

Query: 19  DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78
           ++T +   E +   + + RVLAQD+ ++ ++PPF  S  DGYAVRA D        P + 
Sbjct: 335 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 387

Query: 79  KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130
            +I E  AGE P   V  G  ++V TGA IP GA+AV+  E  +  RE +      ++ +
Sbjct: 388 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 447

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
           L    PGQ++   G D+K+GE +L KGT + P ++ +L  +G+  V V + P V ++ TG
Sbjct: 448 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 507

Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250
           +EL+    ED    GKI ++N   L + + +     I  G++ D  D +  A+ +     
Sbjct: 508 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 565

Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296
           D+++ +GG + G+KDY  + + +  H         +KPG P         G  + +F + 
Sbjct: 566 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 625

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353
           G PV+     +LFV  AL KM G  D     +K R   +  +  +   H  +   +    
Sbjct: 626 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 685

Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390
               +  G+ + S L+    +N  L +P  +E Y    +GE V
Sbjct: 686 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 728


>gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|CAC10537.1|
           (AJ272343) gephyrin [Homo sapiens]
           Length = 769
           
 Score =  164 bits (411), Expect = 2e-39
 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%)

Query: 19  DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78
           ++T +   E +   + + RVLAQD+ ++ ++PPF  S  DGYAVRA D        P + 
Sbjct: 368 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 420

Query: 79  KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130
            +I E  AGE P   V  G  ++V TGA IP GA+AV+  E  +  RE +      ++ +
Sbjct: 421 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 480

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
           L    PGQ++   G D+K+GE +L KGT + P ++ +L  +G+  V V + P V ++ TG
Sbjct: 481 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 540

Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250
           +EL+    ED    GKI ++N   L + + +     I  G++ D  D +  A+ +     
Sbjct: 541 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 598

Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296
           D+++ +GG + G+KDY  + + +  H         +KPG P         G  + +F + 
Sbjct: 599 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 658

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353
           G PV+     +LFV  AL KM G  D     +K R   +  +  +   H  +   +    
Sbjct: 659 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 718

Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390
               +  G+ + S L+    +N  L +P  +E Y    +GE V
Sbjct: 719 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 761


>gi|11435181 gephyrin [Homo sapiens]
           Length = 419
           
 Score =  164 bits (411), Expect = 2e-39
 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%)

Query: 19  DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78
           ++T +   E +   + + RVLAQD+ ++ ++PPF  S  DGYAVRA D        P + 
Sbjct: 18  EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 70

Query: 79  KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130
            +I E  AGE P   V  G  ++V TGA IP GA+AV+  E  +  RE +      ++ +
Sbjct: 71  FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 130

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
           L    PGQ++   G D+K+GE +L KGT + P ++ +L  +G+  V V + P V ++ TG
Sbjct: 131 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 190

Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250
           +EL+    ED    GKI ++N   L + + +     I  G++ D  D +  A+ +     
Sbjct: 191 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 248

Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296
           D+++ +GG + G+KDY  + + +  H         +KPG P         G  + +F + 
Sbjct: 249 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 308

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353
           G PV+     +LFV  AL KM G  D     +K R   +  +  +   H  +   +    
Sbjct: 309 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 368

Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390
               +  G+ + S L+    +N  L +P  +E Y    +GE V
Sbjct: 369 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 411


>gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [Archaeoglobus
           fulgidus] >gi|7445252|pir||A69270 molybdenum cofactor
           biosynthesis protein (moeA-3) homolog - Archaeoglobus
           fulgidus >gi|2650482|gb|AAB91068.1| (AE001095)
           molybdenum cofactor biosynthesis protein (moeA-3)
           [Archaeoglobus fulgidus]
           Length = 400
           
 Score =  162 bits (406), Expect = 6e-39
 Identities = 122/394 (30%), Positives = 204/394 (50%), Gaps = 44/394 (11%)

Query: 24  QDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEE 83
           ++ E V +++AL+R LA+D+ +  D+PPFD + +DGYA++ ED    REY     +++ E
Sbjct: 28  RESEEVRVEDALDRELAEDVFAAKDMPPFDIATMDGYALKLEDG--VREY-----RIVGE 80

Query: 84  VPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFK 143
           V AGE     V  G  + + TGAK+P  A+ V+  E+ + +G K+ +   V  G+ V  K
Sbjct: 81  VYAGEVEDRFVNRGECVYITTGAKMPVNADTVVKVEIAEVDGSKMRIREKVNRGKYVLKK 140

Query: 144 GEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFE 203
           G +VKKG++IL   T + PQ++A L + G++ V V R+ R  +   G E+         +
Sbjct: 141 GSEVKKGDLILPAKTRIGPQEIAALISAGVERVRVFRRLRAAVFSNGDEI---------K 191

Query: 204 EGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGD 263
           +G I ++NS M+ + + K   E    GV  D+ +++RE ++K  R+ D VL +GG + G+
Sbjct: 192 KGIIADSNSAMISAFLRKLGCEVHFLGVAGDDAEEVREMVEKGVRDYDAVLTSGGVSVGE 251

Query: 264 KDYAHRFVK----LLFHGTTIKPGRPIGYG----ERVFIMSGYPVAVFAQFHLFVKHALA 315
           KDY  + +K    +L +    +PG+P+       + VF + G P   F    L ++   A
Sbjct: 252 KDYVVKALKEMGEVLIYKVRQRPGKPMVVAVVNEKPVFALPGKPAGCFTAM-LSLRRFFA 310

Query: 316 KMVGARDYEVKLRAILEDDV--PSQLGRHEFVKVLYRDGKA----------KVI--KKKG 361
              G + +  K+RA +  DV  P++ G   F+ V  RDG A           +I  +K  
Sbjct: 311 ---GDKPFP-KVRARIAGDVKLPTK-GFSYFLFVKLRDGYAIPAGFRHSHVSIIPYEKYE 365

Query: 362 SGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
             ++S++  S             R GEEV + LY
Sbjct: 366 VSLVSAMARSAVSDGFVVTDRDLRAGEEVEVCLY 399


>pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9950098|gb|AAG07301.1|AE004809_1 (AE004809)
           molybdenum cofactor biosynthetic protein A1 [Pseudomonas
           aeruginosa]
           Length = 407
           
 Score =  160 bits (400), Expect = 3e-38
 Identities = 113/371 (30%), Positives = 193/371 (51%), Gaps = 17/371 (4%)

Query: 5   KLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64
           +L P  EAL  LL         E + L+ AL RVL +D+++  D+P +D SA+DGYA+ +
Sbjct: 10  QLRPLDEALAELLARAPRPPACESLALERALGRVLGEDLLAPMDLPHWDNSAMDGYALCS 69

Query: 65  EDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124
            D  +    S   L V   + AG++  M +  G A ++ TGA +P GA+ V+ QE+   +
Sbjct: 70  ADLPR----SGGSLTVGARIAAGDTRGMSLPLGQAARIFTGAPLPTGADCVVPQELCVVD 125

Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184
           GE++  L PV+ GQ+V  +GE++++G  +LR G  LRPQ+L +L +LG+ +V V+R+ R+
Sbjct: 126 GERVQ-LPPVSAGQHVRRRGEELRRGAPVLRAGQRLRPQELGLLASLGVATVSVRRRLRI 184

Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244
           G++ +G EL  EP +     G+I   N   + +L+     E     V+ DE    R+A+ 
Sbjct: 185 GLLSSGDEL-REPGQTLL-AGQIYNANRYCIGALLRGLGFEVHDEEVLADELVASRDALS 242

Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGERV----FIMS 296
            A  E D ++ +GG + G++D+  R +  L         I+PG+P  +G         + 
Sbjct: 243 LAASEWDALVTSGGVSVGEEDHLKRAIAELGEVNLWRLAIQPGKPFAFGSVAGKPWLGLP 302

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI-LEDDVPSQLGRHEFVKV-LYRDGKA 354
           G P A      L  +  L +  G  D   +  A+    D P    R ++++  L   G+ 
Sbjct: 303 GNPAAALVTALLVARPFLLRQQGLFDVVPRPLALPAAFDWPQPRARRQYLRARLDERGRV 362

Query: 355 KVIKKKGSGII 365
           ++  ++GS ++
Sbjct: 363 EIHPQQGSAML 373


>pir||T46858 molybdenum cofactor biosynthesis protein A [imported] - Rhodobacter
           sphaeroides >gi|4185549|gb|AAD09121.1| (AF108766)
           molybdenum cofactor biosynthesis protein A [Rhodobacter
           sphaeroides]
           Length = 394
           
 Score =  157 bits (394), Expect = 2e-37
 Identities = 119/372 (31%), Positives = 187/372 (49%), Gaps = 31/372 (8%)

Query: 26  VEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVP 85
           VE V L EA  RV+A+  ++  D PPFD SA+DGYA+  +    A         V+ E  
Sbjct: 20  VERVALGEARGRVMARPALATRDQPPFDASAMDGYALIGDPPAGAT------FPVVGEAA 73

Query: 86  AGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGE 145
           AG   +  +  G A+++ TGA +PEGA  V++QE V  EG  I +      G ++  +G+
Sbjct: 74  AGHGYEGALRPGEAVRIFTGAPVPEGATRVVLQEDVTAEGGTIRLNAAATGGTHIRPRGQ 133

Query: 146 DVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELV---EEPSEDAF 202
           D + G+ +  +   LRP DLA+L A+ I  V V R+P V +I TG ELV   E P  D  
Sbjct: 134 DFRTGDSLSPRR--LRPNDLALLAAMNIPEVTVTRRPSVALIATGDELVMPGEVPRPD-- 189

Query: 203 EEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFG 262
              +IV +NS  LK+LV     E  L  +  D ED++R  +  A  + DL++  GG++ G
Sbjct: 190 ---QIVASNSFALKALVEAEGAEARLLPIARDTEDELRTVLDLAS-DADLIVTIGGASVG 245

Query: 263 DKDYAHRF-----VKLLFHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQFHLFVKHA 313
           D D   +      ++  F+   ++PG+P+  G      +  + G PV+     HLF+   
Sbjct: 246 DHDLVGKVAAGMGLERAFYKIAMRPGKPLMAGRLRGVPMLGLPGNPVSSIVCAHLFLLPM 305

Query: 314 LAKMVGARDYEVK-LRAILEDDVPSQLGRHEFV--KVLYRDGKAKV--IKKKGSGIISSL 368
           L  M+G        LRA L   +P+   R  ++  ++  +DG  ++     + S ++  L
Sbjct: 306 LRAMLGLPPAPAPLLRAELAVALPANPTRAHYMRARLTRQDGLPRIEPFSSQDSALLRLL 365

Query: 369 VESNAYLEVPED 380
            E++A L  P D
Sbjct: 366 AEADALLVRPVD 377


>emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes]
           Length = 410
           
 Score =  157 bits (392), Expect = 3e-37
 Identities = 122/405 (30%), Positives = 196/405 (48%), Gaps = 35/405 (8%)

Query: 10  REALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQ 69
           R+A++++L     I  V +  L +   ++LAQD+  +  +P FD S +DGYAVR  D  Q
Sbjct: 8   RKAISIMLEHANPIHRVHYTHLFDLTGKILAQDLFCQKALPAFDNSGMDGYAVRLADLGQ 67

Query: 70  AREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVI-MQEMVKREGEKI 128
                  +  ++  + AGES  + +  G   KV+TGA IP G  AVI  +    ++   +
Sbjct: 68  -------KTPILGTILAGESCSVGLHDGACYKVMTGAPIPLGTQAVIPFENATLKDDSTV 120

Query: 129 YVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIII 188
            +      G N+   GE+++ G  +L+KG  L    +A+L + G   +P     R+G+  
Sbjct: 121 LLPTDFKEGANIKIAGEELQVGAPLLQKGERLTHHHVALLASQGYSVLPTYAPLRIGVYS 180

Query: 189 TGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKR 248
           +G+EL+ EP E A +  +I  +N+ ML S +  F       GV+PD  + +REAI +   
Sbjct: 181 SGNELI-EPWESA-QSHQIYNSNASMLFSTLQNFGWRADYLGVLPDCLEGMREAI-RGFD 237

Query: 249 ECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRPIGYG----ERVFIMSGYP 299
             D++L TGG + G+ D+  R ++      LFHG  +KPGRP   G      +  + G P
Sbjct: 238 AYDVILTTGGVSQGEADFMERSLEEAGMTTLFHGIEVKPGRPTMMGILGKTTLLCLPGNP 297

Query: 300 VAVFAQFHLFVKHALAKMVGARDYEV-------KLRAILEDDVPSQ-LGR-HEFVKVLYR 350
           ++     H      L KM G R Y +       K R IL+ +  +  LGR HE      +
Sbjct: 298 LSASINLHFLGIPMLKKMQGERRYHLEFVYAPNKERLILKGNRANMVLGRLHEGCFKATQ 357

Query: 351 DGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395
           +G      K GSG+++ L  SNA +   +  E    G  + +  Y
Sbjct: 358 EG------KYGSGMLTPLTTSNAIIFCDKGVENLEEGALIKVIPY 396


>pir||T44851 molybdopterin co-factor synthesis protein moeA [imported] -
           Arthrobacter nicotinovorans plasmid pAO1
           >gi|4469094|emb|CAA71780.2| (Y10817) molybdopterin
           co-factor synthesis protein [Arthrobacter
           nicotinovorans]
           Length = 430
           
 Score =  156 bits (391), Expect = 3e-37
 Identities = 117/401 (29%), Positives = 195/401 (48%), Gaps = 22/401 (5%)

Query: 2   EFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYA 61
           E + +  +R+A+  +L  +     VE +PL +A+ R LA+ I +  ++PPF  S +DGYA
Sbjct: 29  EHRSVSVHRQAIRDVLFPLLTPPRVERIPLMQAMGRGLAETIHAPTNLPPFTNSQMDGYA 88

Query: 62  VRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMV 121
           VR+ DT   +      L+V   +PAG  P   +  GTA +++TGA IP+GA+AV+  E  
Sbjct: 89  VRSRDTAGGQG----GLRVAAPIPAGAVP-APLVGGTAAQIMTGALIPDGADAVVPVERA 143

Query: 122 KREG------EKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKS 175
                     ++   L  +A G  +   G D+  GE  L  GT+L P+ L +L ALGI  
Sbjct: 144 VPNHFPPPGLDRTVRLPEIAAGTYIRSAGSDIATGECALSAGTVLGPRQLGLLAALGITE 203

Query: 176 VPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDE 235
           V V +K  V +  TG E++E   + A   GKI + N+ +L+S + +     I  G++ DE
Sbjct: 204 VVVNQKLTVLLATTGDEVLEPGEKLAL--GKIYDANNTLLQSSMLQAGLNVIRAGIVKDE 261

Query: 236 EDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFV---KLLFHGTTIKPGRPIGYGE-- 290
              + + ++      DL++ +GG + G  +   + +    + F    I+PG P G G   
Sbjct: 262 PGALSKLLRSHTAHVDLIVTSGGVSAGAYEPVRQAMIDHDVEFSHVAIQPGGPQGVGTFE 321

Query: 291 --RVFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKL--RAILEDDVPSQLGRHEFVK 346
              V    G PV+ F  F +F++  L++M  +      L        DV  +        
Sbjct: 322 GIPVLAFPGNPVSCFVSFEMFLRPLLSEMFASAHTSTLLPRPPFASPDVTPKKAPGFRRG 381

Query: 347 VLYRDGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRG 387
           VL  DG  ++   +GS ++ +L  SN  + +P  + G  +G
Sbjct: 382 VLSADGTIRLEGGEGSHLLGALARSNVLVHIPRGNFGTGQG 422


>sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1480150|emb|CAA67944.1|
           (X99625) moeA [Synechococcus sp.]
           Length = 403
           
 Score =  155 bits (388), Expect = 8e-37
 Identities = 120/400 (30%), Positives = 196/400 (49%), Gaps = 18/400 (4%)

Query: 6   LMPYREALTLLLNDVTEIQ-DVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64
           ++ Y  A+ LLL +V ++   +E VPL E  +R+LA+D+ +  D+P +D SA+DG+A+R+
Sbjct: 2   ILSYSAAIELLLAEVAQLPLAIERVPLLETGDRLLAKDLAAPCDLPHWDNSAMDGFALRS 61

Query: 65  EDTFQAREYSPIELKVIEEVPAGESPKMKVT-SGTAIKVLTGAKIPEGANAVIMQEMVKR 123
           +D   A    P+ L V+  V AGE P +    +G A  V+TGA IP G + ++  E V +
Sbjct: 62  QDVAAASPDRPVRLPVVGRVMAGEQPPLLANPTGVACAVMTGAPIPAGFDVIVKVEDVVQ 121

Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183
           E   I V  P+  GQ +  +GED+++G  +L KG  L P  L +  A+G+  +PV  K  
Sbjct: 122 EENAIAVSTPIPAGQFIRRQGEDLRQGSPLLAKGQRLTPMALMLAAAVGMGELPVWSKLP 181

Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243
           VG+I TG+E+V   S+   E G+I  ++   L   + +   E      +PD+ ++     
Sbjct: 182 VGLISTGTEVVPW-SQPTLELGQIRNSSQPFLIEQLQRLGCEVRAIAHVPDDPEQFAAIA 240

Query: 244 KKA-KRECDLVLVTGGSAFGDKDYAHRFVKLL-----FHGTTIKPGRPIGYG------ER 291
           ++   +   L+L TG  + G  D+    ++ L     FH   I+PG+P+ +         
Sbjct: 241 QQFWSQGVRLLLTTGAVSMGVADFVPAALERLGCQTIFHKVAIRPGKPLLFAIAPEHQGL 300

Query: 292 VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKV-LYR 350
           V    G PV+       F+K  L  M    +    L   L + V    G   F +  L  
Sbjct: 301 VLACPGNPVSTTVTAEFFLKPLL--MACRNEVRSPLWLPLAESVRKPEGLQCFWRSRLTP 358

Query: 351 DGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
           +GK  V  ++ S  + SLVES  +  +P   +    G  V
Sbjct: 359 EGKVWVDPQQSSAALKSLVESTHWAILPAGQDFLAAGTPV 398


>gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus]
           Length = 736
           
 Score =  153 bits (383), Expect = 3e-36
 Identities = 116/403 (28%), Positives = 190/403 (46%), Gaps = 40/403 (9%)

Query: 19  DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78
           ++T +   E +   + + RVLAQD+ ++ ++PPF  S  DGYAVRA D        P + 
Sbjct: 335 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 387

Query: 79  KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130
            +I E  AGE P   V  G  ++V TGA IP GA+AV+  E  +  RE +      ++ +
Sbjct: 388 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 447

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
           L    PGQ++   G D+K+GE +L KGT   P ++ +L  +G+  V V + P V ++ TG
Sbjct: 448 LVQARPGQDIRPIGHDIKRGECVLAKGTHTGPSEVGLLATVGVTEVEVNKFPVVAVMSTG 507

Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250
           +EL+    ED    GKI ++N   L + +       I  G++ D  D +  A+ +     
Sbjct: 508 NELLN--PEDDVLPGKIRDSNRSTLLATIQAHGYPTINLGIVGDNPDDLLNALNERISRA 565

Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296
           D+++ +GG + G K Y  + + +  H         +KPG P         G  + +F + 
Sbjct: 566 DVIITSGGVSMGGKYYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 625

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353
           G  V+     +LFV  AL KM G  D     +K R   +  +  +   H  +   +    
Sbjct: 626 GQSVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 685

Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390
               +  G+ + S L+    +N  L +P  +E Y    +GE V
Sbjct: 686 HPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 728


>pir||A81359 probable molybdopterin biosynthesis protein Cj0857c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968303|emb|CAB73122.1| (AL139076) putative
           molybdopterin biosynthesis protein [Campylobacter
           jejuni]
           Length = 386
           
 Score =  152 bits (381), Expect = 5e-36
 Identities = 110/391 (28%), Positives = 200/391 (51%), Gaps = 26/391 (6%)

Query: 11  EALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQA 70
           E L  L N ++ + + E + L++A +R+LA+D+ +  ++P FD +A+DGYA    D  +A
Sbjct: 6   ETLKDLENQISCLDESELISLEKAKDRILAKDLYARKNLPSFDNAALDGYAFNYTDINEA 65

Query: 71  REYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYV 130
                  L++   + AG+     V      K++TGAK+P+ A+ ++M E    E  K+ +
Sbjct: 66  -------LEIKGTIFAGDKNFYTVAKNECYKIMTGAKMPKNADTILMLEDECIEENKLII 118

Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190
            +         +KGE++KKGE++L+KGT L  + +A+L + G+  + V RK R+GI  +G
Sbjct: 119 KKVPKQYNAYRYKGEELKKGEILLQKGTKLNDKHIALLASQGLYKIEVIRKIRIGIFSSG 178

Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250
           +EL +EP ++  EE  I   N++ L +++          G+I D+    +EA++      
Sbjct: 179 NEL-KEPWQECDEE-SIYNANALPLLTMLQ----NASYLGIIKDDFKSTKEALENT--NF 230

Query: 251 DLVLVTGGSAFGDKDYAHRFV-----KLLFHGTTIKPGRPIGY---GER-VFIMSGYPVA 301
           DL++ +GG++ G+ D+  + +       LF G   +P RP      GE  V I+ G P+A
Sbjct: 231 DLLITSGGASVGEADFMEKALDELGFTPLFKGLKARPARPTKLYRKGENFVLILPGNPMA 290

Query: 302 VFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVI--KK 359
            +    +F K  +  + G  D  +     +  D+  + GR+  +      G        K
Sbjct: 291 AYLSCFIFAKKIINLLSGNLDNPLTFYGKMGMDLKLKSGRNNLILGNLEKGIFTPFNENK 350

Query: 360 KGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
            GSG+I  L++S   L   E++   ++G+E+
Sbjct: 351 FGSGMILPLIKSEFLLISEENTGELKKGDEI 381


>sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MOLYBDENUM COFACTOR
           BIOSYNTHESIS ENZYME CNX1) >gi|1263314|gb|AAA97413.1|
           (L47323) molybdenum cofactor biosynthesis enzyme
           [Arabidopsis thaliana] >gi|4469123|emb|CAB38312.1|
           (AJ236870) molybdenum cofactor biosynthesis enzyme
           [Arabidopsis thaliana]
           Length = 670
           
 Score =  142 bits (354), Expect = 8e-33
 Identities = 118/423 (27%), Positives = 199/423 (46%), Gaps = 46/423 (10%)

Query: 5   KLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64
           +++P  EAL ++      +  V  V L EAL +VLA+DI +   +PP+  S  DGYAV A
Sbjct: 15  EMIPTEEALRIVFGVSKRLPPVI-VSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVA 73

Query: 65  EDTFQAREYSPIELKVIEEVPAG-ESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK- 122
            D        P E  VI E  AG +   + VT GT   V TG  IP GA+AV+  E  K 
Sbjct: 74  SD-------GPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPVGADAVVQVEDTKV 126

Query: 123 -----REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVP 177
                 E +++ +L     G ++   G D++K   +L  G  +   ++ +L   G+  V 
Sbjct: 127 IGDVSTEAKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVK 186

Query: 178 VKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEED 237
           V   P V I+ TG ELV EP+      G+I ++N  ML + V +   + +  G++ D+  
Sbjct: 187 VYPMPIVAILSTGDELV-EPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRK 245

Query: 238 KIREAIKKA-KRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGYGE-- 290
           ++ + + +A     D++L +GG + GD+D+    +    K+ F    +KPG+P+ + E  
Sbjct: 246 ELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIR 305

Query: 291 ------------RVFIMSGYPVAVFAQFHLFVKHALAKMVG-ARDYEVKLRAILEDDVPS 337
                         F + G PV+    F++FV   + ++ G    + +++R  L++ + S
Sbjct: 306 AKPTESMLGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKS 365

Query: 338 QLGRHEFVKVLYR----DGK------AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRG 387
              R EF + + +    DG       A+    + S  + S+  +NA LE+P        G
Sbjct: 366 DPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAG 425

Query: 388 EEV 390
             V
Sbjct: 426 SSV 428


>gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynthesis protein Cnx1 [Hordeum
           vulgare]
           Length = 659
           
 Score =  138 bits (343), Expect = 1e-31
 Identities = 112/398 (28%), Positives = 188/398 (47%), Gaps = 44/398 (11%)

Query: 29  VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88
           VPL +AL  VLA+D  +   +PPF  S  DGYAV A D        P E  VI E  AG+
Sbjct: 25  VPLLDALGLVLAEDARAPDPLPPFRASVKDGYAVVAAD-------GPGEYPVIAEARAGD 77

Query: 89  SPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR-----EGEK-IYVLRPVAPGQNVA 141
               + VT GT   V TG  IP+GA+AV+  E  ++     +G K + +   V  G ++ 
Sbjct: 78  DALGVVVTPGTVAYVTTGGPIPDGADAVVQVEDTEQVAAAPDGSKRVRISARVPEGHDIR 137

Query: 142 FKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDA 201
             G D++K  ++L+ G  + P ++ +L  +G+ +V   R+P + +  TG ELV EP+   
Sbjct: 138 SVGCDIEKDSIVLKSGENIGPAEIGLLATVGVTTVKAYRRPTIAVFSTGDELV-EPATAT 196

Query: 202 FEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKA-KRECDLVLVTGGSA 260
              G+I ++N  ML +   +   + +  G+  D E+ + E +  A   + D++L +GG +
Sbjct: 197 LNRGQIRDSNRAMLLAAAIQQKCKVVDLGIAKDTEESLMEHMDAALHSDADIILTSGGVS 256

Query: 261 FGDKDYAH----RFVKLLFHGTTIKPGRPIGYGE-------------RVFIMSGYPVAVF 303
            GD+D       +  K+ F    +KPG+P+ + E               F + G PV+  
Sbjct: 257 MGDRDLVKPCLAKMGKIHFEKIRMKPGKPLTFAEITSNDTTKPSKTALAFGLPGNPVSCM 316

Query: 304 AQFHLFVKHALAKMVG-ARDYEVKLRAILEDDVPSQLGRHEFVKVLYR----DGK----- 353
             F++FV  A+  + G +  +  ++   +   + +   R EF + + R    DG      
Sbjct: 317 VCFNVFVVPAIRLVSGWSNPHLQRVHVRISHPLRADPHRMEFHRAVIRWVLDDGSGRPGY 376

Query: 354 -AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
            A+    + S  + S+  +NA LEV    +    G  V
Sbjct: 377 VAESTGHQASSRLLSMKSANALLEVQSSGQILAAGASV 414


>emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus]
           Length = 459
           
 Score =  134 bits (335), Expect = 1e-30
 Identities = 95/313 (30%), Positives = 154/313 (48%), Gaps = 22/313 (7%)

Query: 20  VTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELK 79
           V  I D E + L +A  R  A  + +E  +P   RSA+DG+A+R  D   A     + L 
Sbjct: 70  VAPIGDSETLDLAQAAGRTSATSLRAEIALPRAARSAMDGFALRTADLAAA-----LTLP 124

Query: 80  VIEEVPAG-ESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQ 138
           V   V AG ++P +    G A+++ TGA+IP GA+AV+  E V   G ++ +    APG 
Sbjct: 125 VAGTVAAGMQAPPLP--DGAALRIFTGAQIPAGADAVVPVEEVTETGAEVQLTAAPAPGS 182

Query: 139 NVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPS 198
           ++   G +   G ++LR+GT +R   + +L + G+  V V R+PR+ I+ TG EL   P 
Sbjct: 183 HIRAVGSEQPLGGLLLRRGTRIRAHHIGLLASNGVAEVAVVRRPRLAILSTGDEL-HRPG 241

Query: 199 EDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGG 258
            +A     + + N  ML +L      E   +G++PD+ +         +   DL++ TG 
Sbjct: 242 AEAASRDTMPDVNRPMLIALAQGAGAEVDDHGILPDDAEATVAKFASLQGRYDLIVTTGA 301

Query: 259 SAFGDKDYAHRFVKLLFHG-------TTIKPGRPIGYGE----RVFIMSGYPVAVFAQFH 307
            + G +D  H    L+  G         +KPG+P+ +G      V  + G P +    F 
Sbjct: 302 VSMGGRD--HLRPALIAAGGQIDGWKVALKPGKPVMFGRLGNAAVTGLPGNPFSAMVGFT 359

Query: 308 LFVKHALAKMVGA 320
           LFV   +A++ GA
Sbjct: 360 LFVSAQIARLKGA 372


>pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiodurans  (strain
           R1) >gi|6457741|gb|AAF09669.1|AE001871_1 (AE001871)
           molybdopterin biosynthesis MoeA [Deinococcus
           radiodurans]
           Length = 401
           
 Score =  129 bits (321), Expect = 6e-29
 Identities = 112/383 (29%), Positives = 183/383 (47%), Gaps = 30/383 (7%)

Query: 29  VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88
           +PL +AL   L  D+ +    P    SA+DG A R  DT  A   +P+ L+V+ E  AGE
Sbjct: 31  LPLRKALGCTLGADLTALVSHPSATESALDGIACREADTLTASAGAPVALRVVGESRAGE 90

Query: 89  SPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGE--------KIYVLRPVAPGQNV 140
               +V  G  +++ TGA +P G +A+   E + REGE         + +LRP  PG +V
Sbjct: 91  PFAGEVGPGECVRIYTGAPLPPGTDAICPVEQL-REGEGTSAVERGTVELLRPARPG-DV 148

Query: 141 AFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSED 200
             +G D   GE ++  G  L P  LA+  ALG   VPV+R  RV ++ TG E+V  P + 
Sbjct: 149 RPEGGDFHAGETVMSAGLRLTPARLALAAALGHAQVPVRRW-RVALLSTGDEVV-APGQ- 205

Query: 201 AFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSA 260
               G++ ++N + L +L+ +   E +  G  PD    +RE +  A    DL+L +GG +
Sbjct: 206 PLAPGQVYDSNRVGLAALLTEAGYEVLDLGHAPDSPAALRERL-GAAGGADLLLTSGGVS 264

Query: 261 FGDKDYAHRFV----KLLFHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQFHLFVKH 312
            G  D+    +    ++ F    ++PG P   G      VF + G PV+    F + V+ 
Sbjct: 265 MGRYDFMRDLLLGEGEITFWKVKMRPGGPALCGRWGGLPVFGLPGNPVSSLVVFQVIVRP 324

Query: 313 AL-AKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVES 371
            L  + +  R      +        S   +  F + +    + +   ++GSG++ SL ++
Sbjct: 325 VLTGEPLPTR------QVTAATPFASLADKTAFWRGVLSGDEVRDYPRQGSGVLRSLSDA 378

Query: 372 NAYLEVPEDSEGYRRGEEVWITL 394
           +A + VPE  +    GE V + L
Sbjct: 379 DALVVVPE-GQNIAAGERVEVVL 400


>gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulfolobus
           solfataricus]
           Length = 389
           
 Score =  128 bits (319), Expect = 1e-28
 Identities = 107/395 (27%), Positives = 199/395 (50%), Gaps = 24/395 (6%)

Query: 6   LMPYREALTLLLNDVTEIQDVE-HVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64
           L+P  EA  ++ N   E++  E +V + +AL ++  +DI++   +P    SA+DGYA++ 
Sbjct: 3   LIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAIKY 62

Query: 65  EDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124
           +D  +  +     L+V+ ++    S   ++  G    V TG+ +P  A++V+  E  + E
Sbjct: 63  DDYLKYGK-----LRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSRLE 117

Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184
           GE +     V  G+N+  +GED+  G++I++KGT + P  L +L    I  V V    + 
Sbjct: 118 GEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKVS-DLKF 176

Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244
            +   G E+    S +  ++ KI+++ S +L  ++ K FG     GV  D+ + + E I+
Sbjct: 177 TVFANGDEIT---SFENPQKNKIIDSISPILIKILEK-FGSVKYMGVAKDDLNDVTEKIE 232

Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHG---TTIKPGRPIG--YGERVFIM 295
           K+    D+++  GGS+ G+KDY  + V    ++LF G    TIK G  +G   G+ + I+
Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRG-SVGRIQGKPILIL 291

Query: 296 SGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAK 355
            G  V+    FH F    L+ ++G    +     ++ED   +     + V +    G + 
Sbjct: 292 PGQVVSAITAFHEFGLSVLSNILGTNLKKFIKSTLVEDIYVNH--SMDSVYLFNVKGNSA 349

Query: 356 VIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
              + G G+ S L ++N +  + +    Y++GEEV
Sbjct: 350 FPLRWGVGLYSELAKANGF-AILKRGLTYKKGEEV 383


>emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sulfolobus
           solfataricus]
           Length = 389
           
 Score =  128 bits (319), Expect = 1e-28
 Identities = 107/395 (27%), Positives = 199/395 (50%), Gaps = 24/395 (6%)

Query: 6   LMPYREALTLLLNDVTEIQDVE-HVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64
           L+P  EA  ++ N   E++  E +V + +AL ++  +DI++   +P    SA+DGYA++ 
Sbjct: 3   LIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAIKY 62

Query: 65  EDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124
           +D  +  +     L+V+ ++    S   ++  G    V TG+ +P  A++V+  E  + E
Sbjct: 63  DDYLKYGK-----LRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSRLE 117

Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184
           GE +     V  G+N+  +GED+  G++I++KGT + P  L +L    I  V V    + 
Sbjct: 118 GEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKVS-DLKF 176

Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244
            +   G E+    S +  ++ KI+++ S +L  ++ K FG     GV  D+ + + E I+
Sbjct: 177 TVFANGDEIT---SFENPQKNKIIDSISPILIKILEK-FGSVKYMGVAKDDLNDVTEKIE 232

Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHG---TTIKPGRPIG--YGERVFIM 295
           K+    D+++  GGS+ G+KDY  + V    ++LF G    TIK G  +G   G+ + I+
Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRG-SVGRIQGKPILIL 291

Query: 296 SGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAK 355
            G  V+    FH F    L+ ++G    +     ++ED   +     + V +    G + 
Sbjct: 292 PGQVVSAITAFHEFGLSVLSNILGTNLKKFIKSTLVEDIYVNH--SMDSVYLFNVKGNSA 349

Query: 356 VIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390
              + G G+ S L ++N +  + +    Y++GEEV
Sbjct: 350 FPLRWGVGLYSELAKANGF-AILKRGLTYKKGEEV 383


>pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elegans
           >gi|3875564|emb|CAA90060.1| (Z49887) contains similarity
           to Pfam domain: PF00994 (Molybdenum cofactor
           biosynthesis protein), Score=324.9, E-value=3.1e-94,
           N=1~cDNA EST yk255f8.5 comes from this gene~cDNA EST
           yk255f8.3 comes from this gene~cDNA EST yk561c5.3 comes
           from this gene~c> >gi|3879587|emb|CAA90069.1| (Z49889)
           contains similarity to Pfam domain: PF00994 (Molybdenum
           cofactor biosynthesis protein), Score=324.9,
           E-value=3.1e-94, N=1~cDNA EST yk255f8.5 comes from this
           gene~cDNA EST yk255f8.3 comes from this gene~cDNA EST
           yk561c5.3 comes from this gene~c>
           Length = 442
           
 Score =  128 bits (318), Expect = 1e-28
 Identities = 111/391 (28%), Positives = 182/391 (46%), Gaps = 48/391 (12%)

Query: 26  VEHVPLD-EALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEV 84
           VE + +D  AL RV+A+++ S  D+PP   S  DGYAV A D    ++   + L      
Sbjct: 34  VESIQVDWSALGRVVAEEVKSSEDMPPVAASTKDGYAVIAHDGIGLKKMVGVSL------ 87

Query: 85  PAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-------REGEKIYVLRPVAPG 137
            AG   +  V  G  +++ TG  IPEGA+AVIM+E  +        E  +I   + V  G
Sbjct: 88  -AGNIYQGAVEIGKCVRISTGGIIPEGADAVIMREYTELVRQDQQSEETEIICKQAVQVG 146

Query: 138 QNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSE----- 192
           +N+   G DV+  +VI+     +   +  +L A GI+++ V +KP V +I TGSE     
Sbjct: 147 ENIRLPGSDVRSSDVIVPFEAQIGSAEFGILNAFGIRTIKVYKKPVVTVISTGSEVGVIF 206

Query: 193 -LVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECD 251
            ++  P  +    G + ++N+  L +L  +     I  G + D+++ + + + +     D
Sbjct: 207 LVLVSPMVENVPLGMVRDSNAPQLVALFKEHGFNVIDGGRVVDDKEGLDKKLTECLEHSD 266

Query: 252 LVLVTGGSAFGDKDY-----AHRFVKLLFHGTTIKPGRPIGYGER----------VFIMS 296
           +++ TGG + G++DY      H   K+ F   ++KPG P     R          V  + 
Sbjct: 267 VIVTTGGVSMGEQDYMKNALLHLGFKIEFGRVSMKPGLPCTVATRESASERKLKVVLALP 326

Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDY-EVKLRAILEDDVPSQLG-RHEFVKVLYR---- 350
           G P + +   HLF    +  M G R     K+   +  D+  +LG R EFV+        
Sbjct: 327 GNPASAWVCSHLFAVPLIRDMSGYRRINHTKINVRIAQDI--KLGDRPEFVRAFIEQVGD 384

Query: 351 --DGK--AKVIKKKGSGIISSLVESNAYLEV 377
             DG   A V K + S  I +LV +   LE+
Sbjct: 385 EDDGHPIAHVTKNQISSNIGNLVGAQVLLEL 415


>pir||T36508 probable molybdenum cofactor biosynthesis protein - Streptomyces
           coelicolor >gi|5457262|emb|CAB46950.1| (AL096822)
           putative molybdenum cofactor biosynthesis protein
           [Streptomyces coelicolor A3(2)]
           Length = 465
           
 Score =  119 bits (296), Expect = 5e-26
 Identities = 99/372 (26%), Positives = 168/372 (44%), Gaps = 28/372 (7%)

Query: 29  VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88
           VPLD AL   LA  + +  D+P FD SA+DG+AV     +  R+         E V AG 
Sbjct: 93  VPLDAALGLTLAAPLAALTDLPSFDTSAMDGWAVAGPGPWAVRD---------EGVLAGH 143

Query: 89  SPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR-EGEKIYVLRPVAPGQNVAFKGEDV 147
           +    +  G A+++ TGA+IP    AV+  E  +  E  +++  R V  GQ++  +G++ 
Sbjct: 144 AAPAPLIDGEAVRIATGARIPPDTTAVLRTEHGRSDERGRLHPTREVVHGQDIRPRGQEC 203

Query: 148 KKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKI 207
           + G+ +L  GT+  P  L +  A G  ++    +PRV +++ G EL+   ++    +G I
Sbjct: 204 RSGDQLLPVGTLATPAVLGLAAAAGYDTLTAVPRPRVDVLVLGDELL---TQGLPHDGLI 260

Query: 208 VETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYA 267
            +    ML   +     E      I D+   +  A+  +  E DL++ TGG+A G  D+ 
Sbjct: 261 RDALGPMLPPWLRALGAEVRTVRRIGDDAKALHRAVTTS--EADLIVTTGGTAAGPVDHV 318

Query: 268 HRFVK-----LLFHGTTIKPGRP-----IGYGERVFIMSGYPVAVFAQFHLFVKHALAKM 317
           H  ++     LL  G   +PG P     +   + +  + G P+A  +   L +   L + 
Sbjct: 319 HPTLRRIGAELLVDGVKARPGHPMLLARLKDDQHLVGLPGNPLAAVSGL-LTLAEPLLRT 377

Query: 318 VGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVESNAYLEV 377
           + AR         L D V         V V+ R   A  ++  G  ++  +  ++A   V
Sbjct: 378 LAARPAPEPYTLPLRDAVHGHPHDTRLVPVVLRGEGAVPLRYNGPAMLRGIAAADALAVV 437

Query: 378 PEDSEGYRRGEE 389
           P    G R G+E
Sbjct: 438 PPG--GARSGQE 447


>sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7445251|pir||E70601
           probable MoeAprotein - Mycobacterium tuberculosis
           (strain H37RV) >gi|2052128|emb|CAB08154.1| (Z94752) moeA
           [Mycobacterium tuberculosis]
           Length = 426
           
 Score =  114 bits (282), Expect = 2e-24
 Identities = 94/400 (23%), Positives = 181/400 (44%), Gaps = 43/400 (10%)

Query: 29  VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIE----------- 77
           V + EA   + A+++++E  +P FD++A+DGYAVR+ D     +   ++           
Sbjct: 23  VAIAEAQGLMCAEEVVTERPMPGFDQAAIDGYAVRSVDVAGVGDTGGVQVFADHGDLDGR 82

Query: 78  ----LKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRP 133
               L V+  + AG     ++    A++V TGA +P  A+AV+          ++ VLR 
Sbjct: 83  DVLTLPVMGTIEAGARTLSRLQPRQAVRVQTGAPLPTLADAVLPLRWTDGGMSRVRVLRG 142

Query: 134 VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSEL 193
              G  V   G+DV+ G+V +R GTI+    + +L A+G + V V  +PR+ ++  G EL
Sbjct: 143 APSGAYVRRAGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSVMAVGGEL 202

Query: 194 VEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLV 253
           V+         G++ + NS  L +       E    G++ ++  ++ E ++      ++V
Sbjct: 203 VDISRTPG--NGQVYDVNSYALAAAGRDACAEVNRVGIVSNDPTELGEIVEGQLNRAEVV 260

Query: 254 LVTGGSAFGDKDYAHRFVKLLFHGTTIK----PGRPIGYGE------RVFIMSGYPVAVF 303
           ++ GG      +     +  L     ++    PG   G+G+        F++   PV+  
Sbjct: 261 VIAGGVGGAAAEAVRSVLSELGEMEVVRVAMHPGSVQGFGQLGRDGVPTFLLPANPVSAL 320

Query: 304 AQFHLFVKHALAKMVGARDYEVKLRAILE----DDVPSQLGRHEFVK---VLYRDGKAKV 356
             F + V+  +   +G R     +R I+       + S  GR  +++   +  +D    +
Sbjct: 321 VVFEVMVRPLIRLSLGKRH---PMRRIVSARTLSPITSVAGRKGYLRGQLMRDQDSGEYL 377

Query: 357 IKKKG------SGIISSLVESNAYLEVPEDSEGYRRGEEV 390
           ++  G      S ++++L E+N  + VP  +E  R GE V
Sbjct: 378 VQALGGAPGASSHLLATLAEANCLVVVPTGAEQIRTGEIV 417


>sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7470744|pir||S75715
           molybdopterin biosynthesis protein moeA - Synechocystis
           sp.  (strain PCC 6803) >gi|1001210|dbj|BAA10450.1|
           (D64003) molybdopterin biosynthesis MoeA [Synechocystis
           sp.]
           Length = 390
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 101/371 (27%), Positives = 170/371 (45%), Gaps = 25/371 (6%)

Query: 31  LDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESP 90
           +D +  RVLA+ I ++ D PP DR  +DG A+   +  Q R +     K++  V AG   
Sbjct: 25  VDGSYGRVLAESIEADRDYPPGDRVMMDGVALAWSEYHQGRRH----FKLLGTVAAGTPQ 80

Query: 91  KMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVA--PGQNVAFKGEDVK 148
                    ++V+TGA +P+  + VI  E V     ++ ++ P    PG+ V  K  D +
Sbjct: 81  SSLPDQTGCLEVMTGALLPQNCDLVIPYEEVAIADNQVKIINPRQREPGEFVHPKASDCR 140

Query: 149 KGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIV 208
            G+VIL   + L      ++ + G   V VK+KPR+ II TG ELVE   +    + +  
Sbjct: 141 AGKVILESSSKLNGPAWNIITSFGKTKVRVKQKPRIQIISTGDELVEITQKPKIHQLRRS 200

Query: 209 ETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDY-- 266
               + + SL  + F    L  +  D+E  IR   +KAK E  +++ +GG + G  DY  
Sbjct: 201 NIYGLQV-SLQSRGFQNVNLTHLADDKEVIIRH-YQKAKLEYRVLIYSGGISKGKFDYLP 258

Query: 267 ---AHRFVKLLFHGTTIKPGRPIGYG-----ERVFI-MSGYPVAVFAQFHLFVKHALAKM 317
              +   V    HG   KPG+P+ +G     + V I + G P++     H +   + A +
Sbjct: 259 EVWSQLGVTKYIHGVAQKPGKPMYFGIDHRSKTVIIGLPGNPISSLVCLHRYFLDS-API 317

Query: 318 VGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVESNAYLEV 377
                 +   +  L   +P +L       +     KA+ +  K SG   +L  S+ +LE+
Sbjct: 318 YAQLTTDFTFKKDLTYFLPVKLSHTPQAVI-----KAEPLPVKNSGEFIALAGSDGFLEL 372

Query: 378 PEDSEGYRRGE 388
           P+    ++ GE
Sbjct: 373 PQHQASFQAGE 383


>pir||T45454 probable molybdenum cofactor biosynthesis protein [imported] -
           Mycobacterium leprae >gi|4455711|emb|CAB36697.1|
           (AL035500) putative molybdenum cofactor biosynthesis
           protein [Mycobacterium leprae]
           Length = 424
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 98/398 (24%), Positives = 179/398 (44%), Gaps = 41/398 (10%)

Query: 29  VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIE----------- 77
           V + EA   + A+++++E  +P FD++A+DGYAVR+ D     E    E           
Sbjct: 23  VAIAEAQGLMCAEEVMTERPLPGFDQAAIDGYAVRSVDVSGIGESDGGESGSSDEDGRYV 82

Query: 78  --LKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVA 135
             L V+  + AG     ++    A++V TGA +P  A+AV+          ++ +LR   
Sbjct: 83  LTLPVMGTIEAGARTPSRLLPHQAVRVQTGAPLPVLADAVLPVRWTDGGMSRVRILRGAP 142

Query: 136 PGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVE 195
            G  V   G+DV+ G+V +R GTI+    + +L A+G + V V  +PR+ I+  G ELV+
Sbjct: 143 SGAYVRRVGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSIMAVGGELVD 202

Query: 196 EPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLV 255
                    G++ + NS  L +       E    G++ +   +  E ++      ++V++
Sbjct: 203 ISRTPG--NGQVYDVNSYALTAAGRDAGAEVNRIGIVSNNLKEFGEVVEGQISRAEVVVI 260

Query: 256 TGGSAFGDKDYAHRFVKLLFHGTTIK----PGRPIGYGE------RVFIMSGYPVAVFAQ 305
            GG      +     +  +     ++    PG   G+G+        F++   PV+    
Sbjct: 261 AGGVGGAAAEAVRAVLSEIGEMEVVRVAMHPGSVQGFGQLGREGVPTFLLPANPVSALVV 320

Query: 306 FHLFVKHALAKMVGARDYEVKLRAILE----DDVPSQLGRHEFVK-VLYRD---GKAKVI 357
           F + V+  +   +G R     +R I++      + S  GR  +++  L RD   G+  V 
Sbjct: 321 FEVMVRPLIRLSLGKRQ---PMRRIVQARTLSPITSVAGRKGYLRGQLMRDQDTGEYLVQ 377

Query: 358 KKKG-----SGIISSLVESNAYLEVPEDSEGYRRGEEV 390
              G     S ++++L E+N  + +P  +E  R GE V
Sbjct: 378 ALGGALGASSHLLATLAEANCLVVIPSGAEQIRTGEVV 415


>pir||G71966 molybdopterin biosynthesis protein - Helicobacter pylori  (strain
           J99) >gi|4154674|gb|AAD05741.1| (AE001454) MOLYBDOPTERIN
           BIOSYNTHESIS PROTEIN [Helicobacter pylori J99]
           Length = 390
           
 Score =  108 bits (266), Expect = 2e-22
 Identities = 81/333 (24%), Positives = 165/333 (49%), Gaps = 26/333 (7%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           ++ ++EAL +  N   +  +VE V L E+  R+LA+DII    +P F++SA+DGY  + +
Sbjct: 1   MISFKEALKIHSNIPLKPLEVEVVSLFESAGRILAEDIICVHALPKFNQSAMDGYGFKMQ 60

Query: 66  DTFQAREYSPIELKVIEEVPAGES-PKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124
           D  Q       + +VI+ + AG+    ++V     +K++TGA +P+G   ++  E +  E
Sbjct: 61  DLGQ-------KTQVIQHIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECM-LE 112

Query: 125 GEKIYVLRP--VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182
             K + L P       N+  KGE+     V++ K T L    +A++ + G K +   RK 
Sbjct: 113 SHKDFALAPKDFKIHANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGFKEIKAFRKL 172

Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242
           ++ +  +G ELV  P      E ++ + NS+ + +++  +       GV+ D+++   + 
Sbjct: 173 KIALFSSGDELV--PLGQNALECQVYDVNSVGVFNMLKNY--NTHFLGVLKDDKNLQLKI 228

Query: 243 IKKAKRECDLVLVTGGSAFGDKDY-----AHRFVKLLFHGTTIKPGRPIGYGER----VF 293
           ++   +  D++L + G + GDKD+       R     +    +KPG+P+   +     + 
Sbjct: 229 LE--LQGYDVILSSAGVSVGDKDFFKDALKERNALFYYEKVNLKPGKPVTLAQLNQSIII 286

Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARDYEVK 326
            + G P++      + +   L ++   +D+++K
Sbjct: 287 GLPGNPLSCLLVLRVLILPLLERLSLNKDFKLK 319


>pir||F72773 probable molybdopterin biosynthesis protein APE0177 - Aeropyrum
           pernix (strain K1) >gi|5103567|dbj|BAA79088.1|
           (AP000058) 386aa long hypothetical molybdopterin
           biosynthesis protein [Aeropyrum pernix]
           Length = 386
           
 Score =  107 bits (264), Expect = 3e-22
 Identities = 79/257 (30%), Positives = 131/257 (50%), Gaps = 20/257 (7%)

Query: 27  EHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPA 86
           E +P  +++ R+LA+D+ S  D P    +A+DGYAV   D+  A+  + + LK       
Sbjct: 28  EIIPSSQSVGRILAEDLESPNDTPEEPLAAMDGYAV---DSTSAKPGARLRLK------- 77

Query: 87  GESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGED 146
               +  V SG A+ V TG  +P GA+AV+ +E  + E   IYV   V+  +NV   GE 
Sbjct: 78  ---DRGPVASGEAVPVDTGDPLPPGADAVVRREAARVEDGYIYVSAGVSKWENVFRPGEF 134

Query: 147 VKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGK 206
           V +G  +  +G ++ P   A++   G+KSV V R   + ++  GSEL+    E    +G 
Sbjct: 135 VARGSRLASRGDVISPYLAALIMQAGVKSVKVYRIKSI-VMPVGSELLH--PETMTGDGS 191

Query: 207 IVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDY 266
           +     ++   L  + + EP L   +PD  +++ EAI +A  E D+++  GGS+ G +D 
Sbjct: 192 LDYIGPMVTGLL--RGWSEPRLVPPVPDGREELEEAINRALDEADILVTIGGSSVGRRDS 249

Query: 267 AHRFVKLLFHGTTIKPG 283
               V  +  G  + PG
Sbjct: 250 LKALVASM--GQLVVPG 264


>pir||D64541 molybdopterin biosynthesis protein - Helicobacter pylori  (strain
           26695) >gi|2313255|gb|AAD07237.1| (AE000537)
           molybdopterin biosynthesis protein (moeA) [Helicobacter
           pylori 26695]
           Length = 391
           
 Score =  105 bits (260), Expect = 8e-22
 Identities = 75/333 (22%), Positives = 167/333 (49%), Gaps = 26/333 (7%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           ++ ++EAL +  +   +  ++E + L E++ R+LA+DII    +P F++SA+DGY  + +
Sbjct: 1   MISFKEALKIHSSIPIKPLEIEVISLFESIGRILAEDIICIHALPKFNQSAMDGYGFKMQ 60

Query: 66  DTFQAREYSPIELKVIEEVPAGES-PKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124
           D  +       + +V++ + AG+    ++V     +K++TGA +P+G   ++  E +  E
Sbjct: 61  DLGK-------KTQVVQRIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECM-LE 112

Query: 125 GEKIYVLRP--VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182
               + L P       N+  KGE+     V++ K T L    +A++ + G+K +   RK 
Sbjct: 113 SHTNFALAPKDFKINANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGLKEIKAFRKL 172

Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242
           ++ +  +G ELV  P      E ++ + NS+ + +++  +       GV+ D+++   + 
Sbjct: 173 KIALFSSGDELV--PLGQNALECQVYDVNSVGIFNMLKNY--NTHFLGVLKDDKNLQLKI 228

Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRPIGYG----ERVF 293
           ++   ++ D++L + G + GDKD+    +K       +    +KPG+P+         + 
Sbjct: 229 LE--SQDYDVILSSAGVSVGDKDFFKDALKEKNALFYYEKVNLKPGKPVTLARLNQSMII 286

Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARDYEVK 326
            + G P++      + +   L ++   +D+++K
Sbjct: 287 GLPGNPLSCLLVLRVLILPLLERLSLNKDFKLK 319


>emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophila melanogaster]
           Length = 674
           
 Score = 98.3 bits (241), Expect = 1e-19
 Identities = 105/398 (26%), Positives = 186/398 (46%), Gaps = 48/398 (12%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           ++P +E L+++ N V +  +         LN++L + + +  ++PPF  S  DGYA+++ 
Sbjct: 271 MLPVQEVLSIIFNTVQKTAN---------LNKILLE-MNAPVNIPPFRASIKDGYAMKST 320

Query: 66  DTFQAREYSPIELKVIEEVPAGESPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-- 122
                +       +V+  + AG+SP  + +      K+ TGA +P  A+ V+  E  K  
Sbjct: 321 GFSGTK-------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLL 373

Query: 123 ---REGEKIYVLRPVAP--GQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALG-IKSV 176
              + G++  V   V P  G +V   G D+   + I      L P  + +   L  + + 
Sbjct: 374 QLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIF---PALDPSPVVVKSLLASVGNR 430

Query: 177 PVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEE 236
            +  KP+V I+ TGSEL    ++     GKI ++N+ ML  L+  F    +   V+ D  
Sbjct: 431 LILSKPKVAIVSTGSELCSPRNQ--LTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSF 488

Query: 237 DKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-LLFH----GTTIKPGRPIGYGER 291
            + +E++ +     D V+ +GG + GDKD+    ++ L F        IKPG+P+ +  R
Sbjct: 489 QRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASR 548

Query: 292 ----VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI---LEDDVPSQLGRHEF 344
                F + G PV+ F  FHLF   A+    G    +  L  +   L +D  S   R EF
Sbjct: 549 KDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDF-SLDSRPEF 607

Query: 345 VK--VLYRDGK--AKVIKKKGSGIISSLVESNAYLEVP 378
           V+  V+ + G+  A V   + S  + S+V ++  + +P
Sbjct: 608 VRASVISKSGELYASVNGNQISSRLQSIVGADVLINLP 645


>emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaster]
           >gi|7290021|gb|AAF45488.1| (AE003417) cin gene product
           [Drosophila melanogaster]
           Length = 601
           
 Score = 98.3 bits (241), Expect = 1e-19
 Identities = 105/398 (26%), Positives = 186/398 (46%), Gaps = 48/398 (12%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           ++P +E L+++ N V +  +         LN++L + + +  ++PPF  S  DGYA+++ 
Sbjct: 198 MLPVQEVLSIIFNTVQKTAN---------LNKILLE-MNAPVNIPPFRASIKDGYAMKST 247

Query: 66  DTFQAREYSPIELKVIEEVPAGESPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-- 122
                +       +V+  + AG+SP  + +      K+ TGA +P  A+ V+  E  K  
Sbjct: 248 GFSGTK-------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLL 300

Query: 123 ---REGEKIYVLRPVAP--GQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALG-IKSV 176
              + G++  V   V P  G +V   G D+   + I      L P  + +   L  + + 
Sbjct: 301 QLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIF---PALDPSPVVVKSLLASVGNR 357

Query: 177 PVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEE 236
            +  KP+V I+ TGSEL    ++     GKI ++N+ ML  L+  F    +   V+ D  
Sbjct: 358 LILSKPKVAIVSTGSELCSPRNQ--LTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSF 415

Query: 237 DKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-LLFH----GTTIKPGRPIGYGER 291
            + +E++ +     D V+ +GG + GDKD+    ++ L F        IKPG+P+ +  R
Sbjct: 416 QRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASR 475

Query: 292 ----VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI---LEDDVPSQLGRHEF 344
                F + G PV+ F  FHLF   A+    G    +  L  +   L +D  S   R EF
Sbjct: 476 KDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDF-SLDSRPEF 534

Query: 345 VK--VLYRDGK--AKVIKKKGSGIISSLVESNAYLEVP 378
           V+  V+ + G+  A V   + S  + S+V ++  + +P
Sbjct: 535 VRASVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572


>sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAMON
           >gi|1079093|pir||S47896 probable molybdopterin
           biosynthesis protein cinnamon - fruit fly (Drosophila
           melanogaster) >gi|505312|gb|AAA65877.1| (L19876)
           molybdenum cofactor [Drosophila melanogaster]
           Length = 601
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 105/398 (26%), Positives = 186/398 (46%), Gaps = 48/398 (12%)

Query: 6   LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65
           ++P +E L+++ N V +  +         LN++L + + +  ++PPF  S  DGYA+++ 
Sbjct: 198 MLPVQEVLSIIFNTVQKTAN---------LNKILLE-MNAPVNIPPFRASIKDGYAMKST 247

Query: 66  DTFQAREYSPIELKVIEEVPAGESPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-- 122
                +       +V+  + AG+SP  + +      K+ TGA +P  A+ V+  E  K  
Sbjct: 248 GFSGTK-------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLL 300

Query: 123 ---REGEKIYVLRPVAP--GQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALG-IKSV 176
              + G++  V   V P  G +V   G D+   + I      L P  + +   L  + + 
Sbjct: 301 QLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIF---PALDPSPVVVKSLLASVGNR 357

Query: 177 PVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEE 236
            +  KP+V I+ TGSEL    ++     GKI ++N+ ML  L+  F    +   V+ D  
Sbjct: 358 LILSKPKVAIVSTGSELCSPRNQ--LTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDTF 415

Query: 237 DKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-LLFH----GTTIKPGRPIGYGER 291
            + +E++ +     D V+ +GG + GDKD+    ++ L F        IKPG+P+ +  R
Sbjct: 416 QRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASR 475

Query: 292 ----VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI---LEDDVPSQLGRHEF 344
                F + G PV+ F  FHLF   A+    G    +  L  +   L +D  S   R EF
Sbjct: 476 KDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDF-SLDSRPEF 534

Query: 345 VK--VLYRDGK--AKVIKKKGSGIISSLVESNAYLEVP 378
           V+  V+ + G+  A V   + S  + S+V ++  + +P
Sbjct: 535 VRASVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572


>pir||H72739 probable molybdopterin biosynthesis moeA protein APE0450 -
           Aeropyrum pernix (strain K1) >gi|5104096|dbj|BAA79412.1|
           (AP000059) 577aa long hypothetical molybdopterin
           biosynthesis moeA protein [Aeropyrum pernix]
           Length = 577
           
 Score = 96.0 bits (235), Expect = 7e-19
 Identities = 100/379 (26%), Positives = 169/379 (44%), Gaps = 19/379 (5%)

Query: 27  EHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPA 86
           E + L  A+ R LA+  ++    PP+ R  +DG AV +     +R      L+V   +  
Sbjct: 40  ESLGLPAAIGRPLARKAVARGCYPPYPRVNLDGCAVDS-----SRVSRGSVLRVTARLRP 94

Query: 87  GESPKMKVT-SGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPG-QNVAFKG 144
           G  P   V   G  + V TGA +P GA+AV+  E +   GE +  L         VA   
Sbjct: 95  GMEPVELVDREGGCVWVDTGAPLPVGADAVVPLEELDMLGEGVVRLEAEPRRWMGVADPC 154

Query: 145 EDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEE 204
            D   G V+L +G ++ P+ +A L + G+  V    + R  +   G EL     E+  E 
Sbjct: 155 SDAMDGSVVLGEGEVVTPEAVASLASAGVHDVEAGSRLRACVASVGDEL--RSLEECREG 212

Query: 205 GKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRE-CDLVLVTGGSAFGD 263
           G + ETN ++ +S +     E +  G+ PD  + +      A+   C +++ +GGS+ G 
Sbjct: 213 GGVCETNRLLARSRLEAAEVEVVDLGIHPDRPETLSSLAAAARGSGCHILVTSGGSSVGL 272

Query: 264 KDYAHRFVK-LLFHGTTIKPGRP----IGYGERVFIMSGYPVAVFAQFHLFVKHALAKM- 317
            DYA    + ++  G  I+PGRP    I  G  V+ + G P +  +   LF+  +LA   
Sbjct: 273 SDYALAGPEDIVVRGLAIRPGRPTTLSIVDGIPVYSLPGNPRSAGSAIDLFLLPSLAAAG 332

Query: 318 VGARDYEVKLRAILEDDV-PSQLGRHEFVKVLYRDGKAKVIKKKGSGIIS-SLVESNAYL 375
           +        +RA+L   V P +   +  V  +Y  G+   +       ++ S   ++ Y+
Sbjct: 333 LPVATVVPGMRAVLLAGVKPGRRLSYIPVAAVYCGGRLYAVPVSTESYMTVSWAAADGYI 392

Query: 376 EVPEDSEGYRRGEEVWITL 394
            V E  +    GEE  +T+
Sbjct: 393 AV-EPGKALEPGEEASVTI 410


>pir||T42407 gephyrin homolog - Caenorhabditis elegans
           >gi|2811220|gb|AAB97841.1| (AF042069) LIN-46
           [Caenorhabditis elegans] >gi|2811222|gb|AAB97842.1|
           (AF042070) LIN-46 [Caenorhabditis elegans]
           Length = 391
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 82/292 (28%), Positives = 130/292 (44%), Gaps = 24/292 (8%)

Query: 37  RVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTS 96
           R+LA+DII+E+D+P    S VDG+A+        RE   +   V            ++ S
Sbjct: 42  RILAEDIITEYDIPAQRTSIVDGFAIIVNQLGTKREIVGLSTAVTPY-------NAELIS 94

Query: 97  GTAIKVLTGAKIPEGANAVIMQEMVK--REGEKIYVLRPVAPGQNVAFKGEDVKKGEVIL 154
              +++  G  +P+GA+ V+  E V   +E + I VLR    G N+   G + K GE++L
Sbjct: 95  NECVRITIGGVVPDGADTVVPIENVALLKEEKCIEVLRKPKEGDNIREVGSEAKTGEILL 154

Query: 155 RKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIM 214
           + G  L    + +L ALGI  V + +KPRV ++  GS+L       +F   +++E    +
Sbjct: 155 KDGHHLDTMSITLLHALGISQVEIYKKPRVCVLSIGSDLNSNKMYGSFNRSQLLE----L 210

Query: 215 LKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL 274
            +S              I + E+KIR A   A   C LV V G     +     +F K  
Sbjct: 211 FQSQGFTAIDAGSSTEHITEVEEKIRTA---ASFACVLVTVGGAQVIREVAKTLKF-KFE 266

Query: 275 FHGTTIKPGR-PIGYG---ERVFIMSGYP---VAVFAQFHLFVKHALAKMVG 319
                  PG   +  G   E   ++S +P   V+ +   +LFV   L  M G
Sbjct: 267 IQDVDSTPGNFTVSTGKIDETPVVLSIFPEYHVSSWIGANLFVSPILRAMEG 318


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.318    0.139    0.389 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 145821137
Number of Sequences: 2977
Number of extensions: 6366497
Number of successful extensions: 14529
Number of sequences better than 1.0e-10: 63
Number of HSP's better than  0.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 14271
Number of HSP's gapped (non-prelim): 74
length of query: 395
length of database: 189,106,746
effective HSP length: 58
effective length of query: 337
effective length of database: 154,394,500
effective search space: 52030946500
effective search space used: 52030946500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)