BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2014 (moeA-2) DE:molybdenum cofactor biosynthesis protein (moeA-2) (395 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PA... 782 0.0 pir||G71044 probable molybdopterin biosynthesis moeA protein - P... 660 0.0 gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [A... 298 7e-80 pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacte... 291 1e-77 pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PA... 279 3e-74 gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [A... 273 3e-72 pir||B71173 probable molybdopterin biosynthesis moea protein - P... 264 2e-69 sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN... 260 2e-68 pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex... 237 1e-61 sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN... 237 2e-61 pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Meth... 236 4e-61 emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (m... 226 5e-58 dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus ... 217 1e-55 dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis prot... 216 3e-55 gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis prote... 211 1e-53 gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus] 210 2e-53 pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus s... 210 2e-53 emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (m... 203 3e-51 sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 200 3e-50 pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [impo... 192 4e-48 sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 192 6e-48 pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imp... 186 4e-46 sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 185 1e-45 emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri] 182 8e-45 emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [... 180 2e-44 pir||G70829 probable molybdenum cofactor biosynthesis protein - ... 177 2e-43 gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis prote... 176 3e-43 pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [... 174 1e-42 pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [... 173 3e-42 sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 168 8e-41 gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulf... 167 2e-40 sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN L... 164 2e-39 dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens] 164 2e-39 gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens] 164 2e-39 gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|C... 164 2e-39 gi|11435181 gephyrin [Homo sapiens] 164 2e-39 gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [A... 162 6e-39 pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [... 160 3e-38 pir||T46858 molybdenum cofactor biosynthesis protein A [imported... 157 2e-37 emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes] 157 3e-37 pir||T44851 molybdopterin co-factor synthesis protein moeA [impo... 156 3e-37 sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 155 8e-37 gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus] 153 3e-36 pir||A81359 probable molybdopterin biosynthesis protein Cj0857c ... 152 5e-36 sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MO... 142 8e-33 gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynth... 138 1e-31 emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus] 134 1e-30 pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiod... 129 6e-29 gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulf... 128 1e-28 emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sul... 128 1e-28 pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elega... 128 1e-28 pir||T36508 probable molybdenum cofactor biosynthesis protein - ... 119 5e-26 sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 114 2e-24 sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 111 1e-23 pir||T45454 probable molybdenum cofactor biosynthesis protein [i... 110 2e-23 pir||G71966 molybdopterin biosynthesis protein - Helicobacter py... 108 2e-22 pir||F72773 probable molybdopterin biosynthesis protein APE0177 ... 107 3e-22 pir||D64541 molybdopterin biosynthesis protein - Helicobacter py... 105 8e-22 emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophil... 98 1e-19 emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaste... 98 1e-19 sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAM... 98 2e-19 pir||H72739 probable molybdopterin biosynthesis moeA protein APE... 96 7e-19 pir||T42407 gephyrin homolog - Caenorhabditis elegans >gi|281122... 91 2e-17 >pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PAB2014 - Pyrococcus abyssi (strain Orsay) >gi|5457952|emb|CAB49442.1| (AJ248284) molybdenum cofactor biosynthesis protein (moeA-2) [Pyrococcus abyssi] Length = 395 Score = 782 bits (1998), Expect = 0.0 Identities = 395/395 (100%), Positives = 395/395 (100%) Query: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY Sbjct: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 Query: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM Sbjct: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR Sbjct: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR Sbjct: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240 Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV 300 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV Sbjct: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV 300 Query: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK 360 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK Sbjct: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK 360 Query: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY Sbjct: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 >pir||G71044 probable molybdopterin biosynthesis moeA protein - Pyrococcus horikoshii >gi|3258076|dbj|BAA30759.1| (AP000006) 396aa long hypothetical molybdopterin biosynthesis moeA protein [Pyrococcus horikoshii] Length = 396 Score = 660 bits (1685), Expect = 0.0 Identities = 316/395 (80%), Positives = 366/395 (92%) Query: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 MEFKKL+PYREAL LLL+D+ EI+D E VPL EA+ RVLA+DI++EFD+PPFDR+AVDGY Sbjct: 2 MEFKKLVPYREALKLLLDDINEIEDTEKVPLREAVGRVLAEDIVTEFDIPPFDRAAVDGY 61 Query: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 A+RAEDTFQAREY+PIEL VIEEVPAG K +VT+G AIKVLTG +IP+GANAVIMQEM Sbjct: 62 AIRAEDTFQAREYNPIELTVIEEVPAGNVAKEEVTTGKAIKVLTGTRIPKGANAVIMQEM 121 Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 VKREG+KIYVLRPVAPGQN+AF GEDVKKGEV+LRKGTILRPQD+AMLKALGIK VPVK Sbjct: 122 VKREGDKIYVLRPVAPGQNIAFTGEDVKKGEVVLRKGTILRPQDVAMLKALGIKKVPVKV 181 Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240 KP+VGIIITGSEL+EEPSE+ F+EGKIVETNSIML+ LV KFFGEPILYGV+PD+E I+ Sbjct: 182 KPKVGIIITGSELIEEPSEEGFKEGKIVETNSIMLQGLVEKFFGEPILYGVLPDDESIIK 241 Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGERVFIMSGYPV 300 E ++KAK ECD+VL+TGGSAFGDKDYAH+FV LLFHGTTIKPGRP GYGE+VFIMSGYPV Sbjct: 242 ETLEKAKNECDIVLITGGSAFGDKDYAHKFVNLLFHGTTIKPGRPFGYGEKVFIMSGYPV 301 Query: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKK 360 +VFAQF+LFVKHALAKMVGA++YEVK++AIL+DD+PSQLGR+EF+K+ Y +G A+VIKKK Sbjct: 302 SVFAQFNLFVKHALAKMVGAQNYEVKVKAILQDDIPSQLGRYEFIKIYYENGIARVIKKK 361 Query: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 GSGI+SSL+ SNAYLE+PEDSEGYRRGEEVWITLY Sbjct: 362 GSGILSSLLASNAYLEIPEDSEGYRRGEEVWITLY 396 >gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [Archaeoglobus fulgidus] >gi|7429691|pir||B69366 molybdenum cofactor biosynthesis protein (moeA-2) homolog - Archaeoglobus fulgidus >gi|2649666|gb|AAB90308.1| (AE001039) molybdenum cofactor biosynthesis protein (moeA-2) [Archaeoglobus fulgidus] Length = 414 Score = 298 bits (755), Expect = 7e-80 Identities = 173/397 (43%), Positives = 248/397 (61%), Gaps = 19/397 (4%) Query: 11 EALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQA 70 EAL LL + ++ E V + RVLA+DI++ FDVP F+R+A+DGYAV+AEDTF A Sbjct: 15 EALYRLLKKIKALE-TEDVSVYNLQGRVLAEDIVAGFDVPKFNRAAMDGYAVKAEDTFGA 73 Query: 71 REYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYV 130 +PI L++ V GE PK+ V SG A++++TGA +PEG NAV+M E + G + V Sbjct: 74 SVSNPIMLQLAGSVEIGEVPKVVVESGMAVRIMTGAMMPEGTNAVVMLEHTRLNGNFVEV 133 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 L+ V P +NV+ GED+ GEV+ RKG IL+PQD ++ +LGI+SV V RKPRV +I TG Sbjct: 134 LKSVTPMKNVSRVGEDIAAGEVVFRKGEILQPQDAGVIASLGIESVRVYRKPRVAVITTG 193 Query: 191 SELVE--EPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKR 248 +EL E EP E A KI +N+ M+ + + +F E I G+ D+E+++R ++KA Sbjct: 194 NELAEVGEPLEGA----KIYNSNNPMICNALLEFGFEAISLGIARDDEEELRNKLQKA-L 248 Query: 249 ECDLVLVTGGSAFGDK----DYAHRFVKLLFHGTTIKPGRPIG----YGERVFIMSGYPV 300 E D ++TGG++ G K D F +++FHG ++KPG P G G+ VF++ G P Sbjct: 249 EFDAAVITGGTSVGAKDLVPDVVGEFGEIVFHGVSMKPGMPTGAAVVEGKPVFMLPGSPA 308 Query: 301 AVFAQFHLFVKHALAKMVGARDYEVK---LRAILEDDVPSQLGRHEFVKVLYRDGKAKVI 357 A F+ F AL +M+ R K + +L+ +PS++G V+VL+ DGK I Sbjct: 309 AALLGFYTFAIPALYRMMNVRIIARKWSRQKGVLQGRIPSEIGVRSNVRVLWEDGKVYPI 368 Query: 358 KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394 + GSGI+SS V +NA L VPED EGY GEEV +TL Sbjct: 369 RISGSGILSSFVRANALLVVPEDKEGYEEGEEVEVTL 405 >pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622477|gb|AAB85846.1| (AE000899) molybdenum cofactor biosynthesis MoeA [Methanobacterium thermoautotrophicum] Length = 404 Score = 291 bits (736), Expect = 1e-77 Identities = 169/407 (41%), Positives = 252/407 (61%), Gaps = 20/407 (4%) Query: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 M +L+P R+A +L ++ + E V L EA +RVLA DI+S FD PPFDRSA+DGY Sbjct: 1 MFLSELLPVRDAFRIL-DENQRFTEPETVDLLEAYHRVLADDIVSRFDSPPFDRSAMDGY 59 Query: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 AVRAEDTF + +P L+V + + AGE + V G A+++ TGA IP GA+AV+M+E Sbjct: 60 AVRAEDTFGSSPGNPSTLRVTDSIGAGEVSGVDVGHGEAVRIATGAPIPAGADAVVMEEY 119 Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 ++G I VLRPVAP +NVA GEDV++G +LR+GT++RPQ++AM + G V V R Sbjct: 120 TLQDGPDIRVLRPVAPSENVAPAGEDVRRGVTVLREGTLMRPQEIAMAASAGYSKVRVFR 179 Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFG--EPILYGVIPDEEDK 238 +P V +I+TG+ELV +PS+D E GK+ +N L +LV G +P+ +PD+ D Sbjct: 180 RPSVKVIVTGNELV-DPSDD-LEPGKVPNSNLYTLNALVESAGGSADPV---HLPDDIDT 234 Query: 239 IREAIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGYG----E 290 + E I+ + E D+++ TGG+A D V ++LFHG ++PG+P+ +G Sbjct: 235 VGEEIESSASEYDVIITTGGTAISRGDVVVDAVDGLGEVLFHGVALRPGKPVAFGMVSET 294 Query: 291 RVFIMSGYPVAVFAQFHLFVKHALAKM--VGARDYEVKLRAILEDDVPSQLGRHEFVKVL 348 VF++SGYPVA QF +F ++ L +M + R VK R V S GR ++++ Sbjct: 295 PVFMLSGYPVAAMVQFDVFARYYLLRMQHLDYRHRAVKRRC--RAKVASGPGRTDYLRAW 352 Query: 349 YRDGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 D + + ++ +GSGII S+V SNAY+ + E+ EG GEE + L+ Sbjct: 353 ADDEEVEPVQSRGSGIIRSMVGSNAYIVIDENLEGISAGEECDVLLF 399 >pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PAB1436 - Pyrococcus abyssi (strain Orsay) >gi|5458839|emb|CAB50326.1| (AJ248287) molybdenum cofactor biosynthesis protein (moeA-1) [Pyrococcus abyssi] Length = 402 Score = 279 bits (707), Expect = 3e-74 Identities = 159/403 (39%), Positives = 241/403 (59%), Gaps = 12/403 (2%) Query: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 M F K++P AL ++ N T E V L EAL R++A+DI S D+PPFDR+ VDGY Sbjct: 1 MAFLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59 Query: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 AVRAEDTF A E +PI+LKV+ E+ AGE PK+++ G + + TGA +P+ A+AVI E Sbjct: 60 AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119 Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 V+R G++I + +P PG V KG D+ KG +++RKG L + A+L A+G++ V V R Sbjct: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179 Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240 KP+V II TG+E+V SE + G+I + N L V++ GE I G+ D+ + ++ Sbjct: 180 KPKVAIISTGNEIVLPGSE--LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237 Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGE----RV 292 E I++ R D+V+++GG++ G +D ++ L HG I+PG+P GE V Sbjct: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297 Query: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352 F + GYP + F L V L + +G K++A L+ + S GR +F+ V G Sbjct: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357 Query: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 A I KGSG ++S ++++ ++E+PE E GEEV +TL+ Sbjct: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 >gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [Archaeoglobus fulgidus] >gi|7429678|pir||C69366 molybdenum cofactor biosynthesis protein (moeA-1) homolog - Archaeoglobus fulgidus >gi|2649665|gb|AAB90307.1| (AE001039) molybdenum cofactor biosynthesis protein (moeA-1) [Archaeoglobus fulgidus] Length = 654 Score = 273 bits (690), Expect = 3e-72 Identities = 156/407 (38%), Positives = 243/407 (59%), Gaps = 16/407 (3%) Query: 3 FKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAV 62 F+ ++ EA LL N + + E VPL A RVLA+D+ + DVPPFDR+ +DGYAV Sbjct: 5 FRDVVTVDEARGLLFNHFSPRRKTEVVPLHLAAGRVLAKDVYALTDVPPFDRATMDGYAV 64 Query: 63 RAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK 122 RAEDTF+A E SP+ LKV+ V AG+ P+++V SG A+++ TGA +P+GANAV+M E + Sbjct: 65 RAEDTFEAEEDSPVTLKVVGTVEAGKRPELEVESGKAVEIATGAMMPKGANAVVMVEFTR 124 Query: 123 REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182 R ++I + +PV+PG+NV + G DV GE+I R+GT L +++ ++ A GI V V +P Sbjct: 125 RREDEIDIFKPVSPGENVMYAGSDVMAGELIAREGTELTHREIGVMAACGISEVEVYCRP 184 Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242 +V II TG+ELV +P E EGKI + NS + + V + GE IL G+ D E+++R Sbjct: 185 KVAIISTGNELV-KPGE-RLGEGKIYDVNSYSIAAAVEENGGEAILMGIARDNEEEMRSI 242 Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRP----IGYGERVF 293 I KA RE D+V+ +G ++ G D +R + ++ HG IKPG+P + + +F Sbjct: 243 IAKALREADIVITSGSTSAGAGDVMYRILDDFHPGVIVHGIAIKPGKPAVIAVSDSKPIF 302 Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARDYE-VKLRAILEDDVPSQLGRHEFVKVLYRDG 352 + GYP + F + V + ++ G R+ K+RA L V S GR E++ V +G Sbjct: 303 GLPGYPTSAMTVFEVIVAPIIRELAGRRESSGAKVRARLAIKVFSAEGRREYLPVNVVEG 362 Query: 353 ----KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 A + SG +++ ++ ++E+PE+ G+EV + L+ Sbjct: 363 AEGYSAYPVSGSYSGAVTAFAFTDGFVEIPENVVMLEEGDEVEVKLF 409 >pir||B71173 probable molybdopterin biosynthesis moea protein - Pyrococcus horikoshii >gi|3256988|dbj|BAA29671.1| (AP000002) 402aa long hypothetical molybdopterin biosynthesis moea protein [Pyrococcus horikoshii] Length = 402 Score = 264 bits (667), Expect = 2e-69 Identities = 158/403 (39%), Positives = 236/403 (58%), Gaps = 12/403 (2%) Query: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 M F K++P +AL ++ + +E VP+++ L R+ A+DI S DVPPFDR+ VDGY Sbjct: 1 MAFLKVVPLEKALEVVQSFKIS-PGIEEVPIEKGLGRIAAEDIYSPIDVPPFDRATVDGY 59 Query: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 AVRAEDTF A E SP+ LKVI V AGE PK K+ G A + TGA +P A+AVI E Sbjct: 60 AVRAEDTFMASEASPVRLKVIGSVHAGEEPKFKLGKGEAAYISTGAMLPGNADAVIQFED 119 Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 V+R +I + +P PG V KG D++KG ++++KG L + A+L A+GI V V R Sbjct: 120 VERVNGEILIYKPAYPGLGVMKKGIDIEKGRLLVKKGERLGFKQTALLSAVGINKVKVFR 179 Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240 KP+V +I TG+E+V P + + G+I + N L +++ GE I GV D+++ ++ Sbjct: 180 KPKVAVISTGNEIV--PPGNELKPGQIYDINGRALCDAINELGGEGIFMGVARDDKESLK 237 Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRP--IGY--GERV 292 I+KA D+V+++GG++ G KD ++ L HG I+PG+P IG G+ V Sbjct: 238 ALIEKAVNVGDVVVISGGASGGTKDLTASVIEELGEVKVHGIAIQPGKPTIIGVIKGKPV 297 Query: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352 F + GYP + F L V L + +G K A L+ V S GR +F+ V +G Sbjct: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKIGKKVARLKHKVFSVKGRRQFLPVKL-EG 356 Query: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 V KGSG ++S ++++ ++E+PE E GEEV +TL+ Sbjct: 357 DLAVPILKGSGAVTSFIDADGFVEIPETVESLDEGEEVEVTLF 399 >sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0666 >gi|2129130|pir||B64383 molybdenum cofactor biosynthesis protein moeA homolog - Methanococcus jannaschii >gi|1591380|gb|AAB98661.1| (U67514) molybdenum cofactor biosynthesis protein (moeA) [Methanococcus jannaschii] Length = 398 Score = 260 bits (657), Expect = 2e-68 Identities = 159/409 (38%), Positives = 248/409 (59%), Gaps = 35/409 (8%) Query: 4 KKLMPYREALTLLLNDVTEIQD----VEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDG 59 K LMP + A ++ ++E D V+ V + EALNR+ A+DI + D+P F+++A+DG Sbjct: 5 KNLMPLKSAEKIVFEKLSEYLDENKKVKEVDIVEALNRISAEDIKAPIDLPYFNKAAMDG 64 Query: 60 YAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQE 119 YAV AEDTF A E +PI L + + G+ ++T G A K+ TG K+P+ ANAV+M+E Sbjct: 65 YAVIAEDTFGASETNPIILNLAD----GD----EITYGEAKKIFTGDKLPKNANAVVMKE 116 Query: 120 MVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVK 179 + + V + V P +NV+ GEDVKKG+V+L+KG I+ P L ML +LGIK + V Sbjct: 117 FCNEVDDFVEVYKTVHPNENVSRIGEDVKKGDVVLKKGEIINPYHLNMLASLGIKKIKV- 175 Query: 180 RKPRVGIIITGSEL-----VEEPSEDAFE-EGKIVETNSIMLKSLVHKFFGEPILYGVIP 233 GII TG EL + + ED + +GKI+ +NS ML LV +Y ++ Sbjct: 176 YDLSFGIISTGDELINLDEIRDIEEDISKLDGKIINSNSYMLYGLVKNLGFNAKIYDIVK 235 Query: 234 DEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYG 289 D+++K+++AIK A E D +L+TGG++ ++D V+ ++ HG I+PG+P G+G Sbjct: 236 DDKEKLKKAIKTALSENDALLITGGTSVSERDITVETVRELGDVIVHGVNIRPGKPFGFG 295 Query: 290 ----ERVFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFV 345 + VF++SGYPVA QF LF++ + K+ L+ ++ S+LGR +FV Sbjct: 296 IINDKPVFMLSGYPVASAVQFELFIQRFFIE-------RKKVTLPLKRNMASELGRVDFV 348 Query: 346 KVLYRDGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394 +V D + + I+ GSG+ISSL++S+ Y+ +PE+ EGY +GE V + L Sbjct: 349 RVKV-DIEVEPIRITGSGVISSLIKSDGYILIPENVEGYEKGELVDVYL 396 >pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex aeolicus >gi|2982782|gb|AAC06407.1| (AE000670) molybdenum cofactor biosynthesis protein A [Aquifex aeolicus] Length = 402 Score = 237 bits (599), Expect = 1e-61 Identities = 154/408 (37%), Positives = 232/408 (56%), Gaps = 23/408 (5%) Query: 4 KKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVR 63 K L P EAL ++L +V ++ E V + EAL RVLA+D++S+ D P FD SA+DGYAVR Sbjct: 2 KNLTPLEEALKIVLENVKPLES-ERVFIHEALGRVLAEDVVSDTDKPLFDNSAMDGYAVR 60 Query: 64 AEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR 123 ED + P +LKVI E AG +KV GTA+K+ TGA IPEGA+ V+ E + Sbjct: 61 WEDIKEV----PAKLKVIGEYAAGTGENLKVEKGTAVKIFTGAPIPEGADTVVPVEYTET 116 Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183 + + V + G NV +GEDVKKGEV++ KG +RP ++ ML ++ V V RKP Sbjct: 117 QDGYVIVKKSFKQGANVRRRGEDVKKGEVVIPKGKEIRPYEMGMLASVNRAVVSVYRKPH 176 Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243 VGI+ TG E++ + E+ + +I +N+ + V + G P G+ PDE K++E I Sbjct: 177 VGILSTGDEIL-DVCEEQTKPSQIRTSNNYTVYGQVLQAGGIPHNLGIAPDEPQKLKE-I 234 Query: 244 KKAKRECDLVLVTGGSAFGDKDYAHRFVKLL-----FHGTTIKPGRPIGYG-----ERVF 293 ++ + D+ + TGG + G+KDY V+ L FH IKP +P+ +G + F Sbjct: 235 MRSIHKYDIFITTGGVSMGEKDYVQYLVEDLGIDVKFHKLRIKPAKPVLFGVYGENKLFF 294 Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARD-YEVKLRAILEDDV-PSQLGRHEFV--KVLY 349 + G PV+ F L V A+ M G R+ ++ K+ AILE D R EF +V + Sbjct: 295 GLPGNPVSAAVAFDLLVYPAIKAMQGHREVFKQKVTAILEGDYRRKNADRREFARCRVWF 354 Query: 350 RDGK--AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 +G+ + K+ S +++SLV SNAY+ V E ++G+EV + L+ Sbjct: 355 ENGRYHCEPYPKQDSHMLTSLVNSNAYMVVYEGVNELKKGQEVEVILF 402 >sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0886 >gi|2129131|pir||F64410 molybdenum cofactor biosynthesis protein moeA homolog - Methanococcus jannaschii >gi|1591564|gb|AAB98890.1| (U67532) molybdenum cofactor biosynthesis protein (moeA) [Methanococcus jannaschii] Length = 620 Score = 237 bits (598), Expect = 2e-61 Identities = 140/398 (35%), Positives = 236/398 (59%), Gaps = 27/398 (6%) Query: 11 EALTLLLNDVTEIQ-DVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQ 69 EA +++ + +++ +VE V L A+ RVLA+D+ S D+PP+DR+ +DGYAV+AEDT++ Sbjct: 12 EAKSIINESLKKLKNEVEEVDLFNAIGRVLAEDVFSNIDIPPYDRAKMDGYAVKAEDTYE 71 Query: 70 AREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIY 129 A E +P+ELKVI + AGE +++ +G +++ TGA IP+GANAV+M E +R+ +++ Sbjct: 72 ADEDNPVELKVIGSLKAGEIKDLEINNGECVEIATGAIIPKGANAVVMVEYTERDNDRVK 131 Query: 130 VLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIIT 189 + R V P +N+ F G D+ GE++LRK T L P+D+ +L A+G V V +K + GII T Sbjct: 132 IYRAVPPMENIQFTGSDIMAGELVLRKNTKLTPRDIGVLAAIGKSKVKVYKKLKFGIIST 191 Query: 190 GSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRE 249 G+E++ P+E E GKI + NS L S + + +G+ D++++++E IKKA + Sbjct: 192 GNEII-SPNEQ-LEFGKIYDINSYTLVSYIKTLGYDFEFFGIAKDDKEELKEKIKKALK- 248 Query: 250 CDLVLVTGGSAFGDKDYAHRFV-----KLLFHGTTIKPGRPIGYG----ERVFIMSGYPV 300 CD++L++GG++ G D + K+L HG IKPG+P G + + + GYP Sbjct: 249 CDIILLSGGTSAGVGDLTETAIKELGGKILVHGIKIKPGKPTIIGKIDNKLIVGLPGYPT 308 Query: 301 AVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVL---YRDGKAKVI 357 + F + D + ++A S GR E++ V+ +++G + Sbjct: 309 SCLTIFDVLF----------GDEKNVVKAKFPVRYISAKGRVEYLPVILVKHKNGFSAYP 358 Query: 358 KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 KGSG I+SL E++ Y+ + E+ E E+V + L+ Sbjct: 359 ITKGSGAITSLSEADGYIIIDENKE-ILENEDVEVHLF 395 >pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622104|gb|AAB85499.1| (AE000873) molybdenum cofactor biosynthesis protein MoeA [Methanobacterium thermoautotrophicum] Length = 409 Score = 236 bits (595), Expect = 4e-61 Identities = 138/381 (36%), Positives = 220/381 (57%), Gaps = 12/381 (3%) Query: 24 QDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEE 83 Q E V + +A RVLA DI S D+PPFDR++ DGYAVRA DTF A E +P L+ IE Sbjct: 29 QGTESVDILDADGRVLADDIESPVDLPPFDRASRDGYAVRAADTFGADEENPATLRCIET 88 Query: 84 VPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFK 143 V AG P ++V G ++ TGA +PEGA+AV+M E E +++Y+ RP P Q++A + Sbjct: 89 VEAGSVPSLEVAEGLCTRISTGAPVPEGADAVVMVEYTWEEVDRVYIQRPAYPSQHIAAR 148 Query: 144 GEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFE 203 G D++ G V+LR GT+L P +A L A GI V V KP V +I TG+EL+E + E Sbjct: 149 GSDIRAGNVLLRTGTVLSPDKIAALSAAGITRVNVISKPSVCVISTGNELIEPSGQ--LE 206 Query: 204 EGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGD 263 GKI ++NS L S + + G++ D+ ++R+AI + E D+V+ +GG++ G Sbjct: 207 PGKIFDSNSAGLSSALKEAGCSVKHGGIVRDDYGELRDAILRGLEEADMVITSGGTSAGA 266 Query: 264 KDYAHRFV----KLLFHGTTIKPGRPIGYG---ERVFI-MSGYPVAVFAQFHLFVKHALA 315 D + +++ HG +IKPG+P G +++ + + G+PV+ F ++ + Sbjct: 267 GDILSEVLDELGRVVIHGISIKPGKPTIVGVVDDKIVVGLPGFPVSALIVFMSLIEPFIR 326 Query: 316 KMVGARDYEVKLRAI-LEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVESNAY 374 K+ G + ++ + L + + S GR + V+ A+ I K SG +++L ++ Y Sbjct: 327 KLSGRKASSGHVKTLKLAERLHSSRGRVHYALVMVDGDYARPI-FKDSGAVAALAGADGY 385 Query: 375 LEVPEDSEGYRRGEEVWITLY 395 +EVP++ E GEEV + L+ Sbjct: 386 IEVPKNVEIINEGEEVEVVLF 406 >emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (moeA-2) related protein [Thermoplasma acidophilum] Length = 399 Score = 226 bits (569), Expect = 5e-58 Identities = 138/403 (34%), Positives = 221/403 (54%), Gaps = 26/403 (6%) Query: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 MEFK L PY EA+ + +++ +V + E++ R ++D++S D P DRSAVDG Sbjct: 1 MEFKSLTPYGEAIRMASGLRINVRE-SYVSVAESVGRYCSRDVVSPVDFPEADRSAVDGI 59 Query: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 A+R ED+ A +PI+L ++ EV G+SP ++ G V TG+ IPEGANAV+M+E Sbjct: 60 ALRYEDSLSASRSNPIQLSLVGEVRIGDSPAFRINRGECAIVYTGSPIPEGANAVLMKED 119 Query: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 + V R + QN++ GED+K+G+ I+++G+ + P L GI VPV Sbjct: 120 ASIGKSMVSVYRQMKKFQNISRAGEDLKRGDTIIKRGSRIMPWHLPAFIESGIDKVPV-M 178 Query: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240 +GI+ TG+E+V G + +++ ML++++ + + YG + D+E +IR Sbjct: 179 DAEIGIVSTGTEIV---------RGLVKNSSAPMLEAMISRMGLKSAFYGNVEDDESRIR 229 Query: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGY----GERV 292 I+ K D+++VTGGS +D H + +L+FHG +KPGR G G+ V Sbjct: 230 SVIEGMK--SDIIIVTGGSGPSSQDLVHDIIASNGQLIFHGVRMKPGRTTGLGMMDGKPV 287 Query: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKL-RAILEDDVPSQLGRHEFVKV--LY 349 F++SG PVA F + A+ G + E + R L + + FV+V Sbjct: 288 FMISGLPVAALIAFENIIDPAIRSWFGMKSLERRTRRGYLTRSIFNNENMRMFVRVRMFE 347 Query: 350 RDGKAKV--IKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 DGK V ++ GSG+I+S++ ++ YL + E+SEGY G EV Sbjct: 348 EDGKTMVEPMRTTGSGVINSVISADGYLVIEENSEGYPEGAEV 390 >dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus halodurans] Length = 423 Score = 217 bits (548), Expect = 1e-55 Identities = 138/407 (33%), Positives = 226/407 (54%), Gaps = 23/407 (5%) Query: 7 MPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAED 66 +P EA+ ++ E + +E VPL+EA R LAQ ++++ +VPPFD+S +DG+A+RA D Sbjct: 8 IPVHEAVEQVVAFAKE-RAMEWVPLEEADGRFLAQPLVADHNVPPFDKSPLDGFAIRAVD 66 Query: 67 TFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGE 126 T A +P+ LK+IEE+ AG+ + + G AI+++TGA++PEG +AV+M E+ K E Sbjct: 67 TEDATRETPVRLKIIEEIGAGQVAQKVPSQGEAIRIMTGAQMPEGTDAVVMFELTKEISE 126 Query: 127 K----IYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182 I V R PG N++F GED K+G ++ KG + A+L G VPV + P Sbjct: 127 AGESFIEVKRSFQPGDNISFCGEDAKEGTPLVEKGRQIDAGIKALLATFGYAKVPVYKMP 186 Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242 ++GI TG+EL+E ++ GKI +N+ M+ S V + EP+ G + D+ D+ +A Sbjct: 187 KIGIFATGTELLE--VDEPLVPGKIRNSNAYMVASQVKQIGAEPVYLGKLVDDFDQCYDA 244 Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRF-----VKLLFHGTTIKPGRPIGYGER----VF 293 I A + D+++ TGG + GD DY +LF+ ++PG ER +F Sbjct: 245 IATALADVDVLVTTGGVSVGDYDYLPAIYEKLGANVLFNKIAMRPGSVTTVAEREGQLLF 304 Query: 294 IMSGYPVAVFAQFHLFVKHAL-AKMVGARDYEVKLRAILEDDVPSQLGRHEFVK--VLYR 350 +SG P A F F L V+ + + + +++A L D P FV+ V ++ Sbjct: 305 GLSGNPSACFVGFELLVRPFIHVGFCSEQPFLKRVKATLGRDFPKPNPFTRFVRSQVEFK 364 Query: 351 DGKAKVIKKKG---SGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394 + ++K G SG+++SL +N L +P + G++ G+EV + L Sbjct: 365 IDRL-IVKPTGLDKSGVVTSLANANGLLMLPGGTRGFQAGDEVDVLL 410 >dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis protein [Clostridium perfringens] Length = 406 Score = 216 bits (545), Expect = 3e-55 Identities = 136/403 (33%), Positives = 226/403 (55%), Gaps = 19/403 (4%) Query: 4 KKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVR 63 KK + EAL +L N T+ E V + ++L RVL D+ S+ + PPF++S DGYA + Sbjct: 2 KKFIALEEALEIL-NKNTKALKSEVVSIKDSLKRVLYGDVKSKINNPPFNKSVFDGYAFK 60 Query: 64 AEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR 123 +ED+ + +PIELK+++E+ AG+ ++++ G AI+++TGA IP GA+ V+ QE +R Sbjct: 61 SEDSKGTSKENPIELKIVDEIFAGDFSEIEIKHGEAIRIMTGAPIPVGADCVLKQEETER 120 Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183 G+ + + + + +N++F GED+K GE +++KG L DL ++ + GI V V +KP+ Sbjct: 121 HGDLVKIFKEMKANENISFMGEDIKIGETLIKKGKRLDYADLGIMASSGISEVLVYKKPK 180 Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243 V II TG E+ + S + GKI ++N L + + + + + D KI EAI Sbjct: 181 VSIISTGDEVCDINS--TLKPGKIYDSNLYSLSARIEELGYNVLSMEHVGDNILKIGEAI 238 Query: 244 KKAKRECDLVLVTGGSAFGDKDYAHRF-----VKLLFHGTTIKPGRPIGYGER----VFI 294 +KA + D+V TGG++ G+KD + + LF IKPG + +R + Sbjct: 239 EKAFEKSDIVFTTGGASVGEKDLMQKVSGSIGFERLFWKIKIKPGSAVVCSKRQEKILIS 298 Query: 295 MSGYPVAVFAQFHLFVKHALAKMVGARD-YEVKL-RAILEDDVPSQLGRHEFVK--VLYR 350 +SG P A F L K L K+ G + +K + +L D + + F++ ++Y Sbjct: 299 LSGNPNAALTTFELLGKPVLKKLEGEEENINIKREKGVLMDSFNKKSPQRRFLRGNIIYD 358 Query: 351 DGKAKVI---KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 + AKV K G+GI+SSL+ +N +E+ + +EG RGE V Sbjct: 359 EKGAKVYITQIKSGNGILSSLLNANCLIEIEKGNEGLNRGEVV 401 >gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis protein; MoeA1 [Halobacterium sp. NRC-1] Length = 407 Score = 211 bits (531), Expect = 1e-53 Identities = 145/404 (35%), Positives = 216/404 (52%), Gaps = 31/404 (7%) Query: 3 FKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAV 62 FK+ EA LL+ V + V L +A RVLA D+ + VP ++R+A+DG+AV Sbjct: 10 FKQRTRVAEARERLLSAVDPLARTARVALGDADGRVLAADVEAPRAVPHYERAAMDGFAV 69 Query: 63 RAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK 122 RA DTF A + SP+ L +V G V G A++V TG+++P GA+AV+M E + Sbjct: 70 RAADTFGAGDRSPVVL----DVGTGS-----VGPGEAVRVHTGSELPAGADAVVMIEDAE 120 Query: 123 REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182 R G+++ V A G NVA GEDV G+ + G LRP DL +LK+ G+ +V V +P Sbjct: 121 RRGDRVDVFAAAAGGANVAPIGEDVSDGQHLYDAGHRLRPSDLGLLKSAGVDAVAVYERP 180 Query: 183 RVGIIITGSELV-EEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIRE 241 VG++ TG ELV +P G++VETN + V ++ G P GV+ D+E +R Sbjct: 181 TVGVLPTGEELVAADPG-----PGEVVETNGGTVAQYVSRWGGVPTRRGVVTDDEAALRT 235 Query: 242 AIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGY----GERVF 293 AI++A D+V+ TGGS+ G +D+ + +L HG ++PG P+ V Sbjct: 236 AIREAVDSHDVVVTTGGSSVGARDHVPEVIADLGTVLVHGVALQPGHPVALCVVDDTPVV 295 Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVG--ARDYEVKLRAILEDDVPSQLGRHEFVKVLY-- 349 + GYPVA F++ L K VG A+L + S+ G FV+V Sbjct: 296 ALPGYPVAAIVNAVQFLR-PLLKAVGHAPATAHPTTDAVLARKIASEPGTRSFVRVTRHG 354 Query: 350 -RDGKAKVIKKK--GSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 DG+ V + GSG++SS+ ++ ++ VPED EGY G V Sbjct: 355 DEDGRPTVTPTRAGGSGVLSSVALADGWVVVPEDCEGYDAGTTV 398 >gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus] Length = 419 Score = 210 bits (530), Expect = 2e-53 Identities = 131/409 (32%), Positives = 228/409 (55%), Gaps = 19/409 (4%) Query: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 +E + +P REA+ ++ E + V++VPL+++L VLA+DI++ +++P F++S DG+ Sbjct: 3 VEKRNPIPVREAIKRVVEQDIETE-VQNVPLNKSLGYVLAEDIVATYEIPRFNKSPYDGF 61 Query: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 A+R+EDT A + IE +VI+ + AG V A++++TGA++P GA+AV+M E Sbjct: 62 ALRSEDTVGASGDNRIEFEVIDHIGAGSVSDKTVGPNQAVRIMTGAEVPAGADAVVMLEQ 121 Query: 121 VKREGEKIYVLRPV-APGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVK 179 K EG+ + +R + +NV+ KGE+ + G+V+L+KG + +A+L G VPV+ Sbjct: 122 TK-EGDHTFTIRKTFSHNENVSLKGEETEVGDVVLKKGQRINAGGIAVLATFGYTEVPVR 180 Query: 180 RKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKI 239 + P II TGSEL++ D E GKI +N M++ L+++F + +Y + D+ + Sbjct: 181 KLPSAAIIATGSELLD--VGDELEPGKIRNSNGPMIEGLLNQFGLDGEVYKIQEDDLESS 238 Query: 240 REAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGR----PIGYGE 290 +K+A D+V+ TGG + GD DY K +LF+ ++PG + +G+ Sbjct: 239 IAVVKQAMETHDMVITTGGVSVGDFDYLPEIYKALDAEVLFNKVQMRPGSVTTVAVAHGK 298 Query: 291 RVFIMSGYPVAVFAQFHLFVKHALAKMVGARD-YEVKLRAILEDDVPSQLGRHEFV--KV 347 +F +SG P A + F LFVK + M+GA + + ++A L +D F+ K Sbjct: 299 YLFGLSGNPSACYTGFQLFVKTGVLNMMGANEKFPQVVKATLMEDFKKANPFTRFIRSKA 358 Query: 348 LYRDGKAKVIKK--KGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394 +A V+ SG + ++ SNA + +P + G+ G V + L Sbjct: 359 TLNGMEATVVPSGFNKSGAVVAIAHSNAMVMLPSGTRGFHAGNTVDVIL 407 >pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus subtilis >gi|2633799|emb|CAB13301.1| (Z99111) molybdopterin biosynthesis protein [Bacillus subtilis] >gi|3282112|gb|AAC24902.1| (AF012285) molybdopterin biosynthesis protein MoeA [Bacillus subtilis] Length = 430 Score = 210 bits (529), Expect = 2e-53 Identities = 135/388 (34%), Positives = 212/388 (53%), Gaps = 20/388 (5%) Query: 25 DVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEV 84 + E V L+++L+R LA+DI ++ VP FDRS DG+AVRA DT +A +P+ +VI+ + Sbjct: 25 ETEWVALEDSLHRFLAEDITADHHVPAFDRSPYDGFAVRACDTAEASRENPVRFEVIDHI 84 Query: 85 PAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEK----IYVLRPVAPGQNV 140 AG + ++ A++++TGA+IPEGA+AV+M E+ + E + + R G N+ Sbjct: 85 GAGAVSEKELGPFQAVRIMTGAQIPEGADAVVMIELTQAFEENGKSFMSLKRRFQTGDNI 144 Query: 141 AFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSED 200 + GED +KG V+L KGT + P A+L G SVPV RKP VGII TG+EL+ D Sbjct: 145 SKTGEDAQKGSVLLTKGTRVTPGVTALLATFGYASVPVVRKPVVGIIATGTELLN--VSD 202 Query: 201 AFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSA 260 E GKI +N+ M+ + + P+ G I DE DK A+K+A ++ D ++ TGG + Sbjct: 203 PLEPGKIRNSNASMVYAQAIEAGATPLYLGKISDELDKSFAAVKEAMKKVDFLITTGGVS 262 Query: 261 FGDKD-----YAHRFVKLLFHGTTIKPGRPIGYGER----VFIMSGYPVAVFAQFHLFVK 311 GD D Y +LF+ ++PG +F +SG P A + F LFVK Sbjct: 263 VGDFDFLPAIYEKLGADVLFNKVAMRPGSVTTVAHANDMLLFGLSGNPSACYVGFELFVK 322 Query: 312 HALAK-MVGARDYEVKLRAILEDDVPSQLGRHEFVKVL--YRDGK--AKVIKKKGSGIIS 366 + ++ + + A+L D P FV+ L +++GK A + S ++ Sbjct: 323 PIIQTWLLNETPHSICAEAVLTKDFPKPNPFTRFVRALVHHQEGKLLATPVGLDKSSSVT 382 Query: 367 SLVESNAYLEVPEDSEGYRRGEEVWITL 394 SL ++NA++ +P + GY G V + L Sbjct: 383 SLADANAFIILPGGTRGYESGRTVQVLL 410 >emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (moeA-1) related protein [Thermoplasma acidophilum] Length = 626 Score = 203 bits (511), Expect = 3e-51 Identities = 118/398 (29%), Positives = 219/398 (54%), Gaps = 13/398 (3%) Query: 3 FKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAV 62 F +L+ +A +++ ++ ++ V VP++EA+ A+DI S++DVPPFDRS VDG+AV Sbjct: 4 FHRLVSAEDARSIMAGEMRKLMRVVEVPIEEAVGLTAAEDIFSQYDVPPFDRSEVDGFAV 63 Query: 63 RAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK 122 D A+E +P+ L++ + GE+ + V G A+ + TG+ +P+G++AV+M E + Sbjct: 64 DHADVDGAQEDAPVTLRIAGSISPGETGNVTVERGKAVYIATGSVMPKGSDAVVMVEDTR 123 Query: 123 REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182 + G+ + + R V PG+NVAF G D+ G++I + GT+L P+ LA L A G+ V V + Sbjct: 124 QHGDYVDIYRSVYPGENVAFAGTDISLGDIIAKAGTVLTPEKLATLAASGVARVRVFDRI 183 Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFG-EPILYGVIPDEEDKIRE 241 R+GI TG+E+V + + G+I + N ++ + G + G +PD ED + + Sbjct: 184 RIGIFSTGNEIVRPGTN--LKLGQIFDVNGYYFQTKLSSSGGVHAVFLGSVPDREDDMVK 241 Query: 242 AIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRPIGY---GERVF 293 I+ D+++ +G ++ G D +R ++ +LFHG ++PG+P + GE++F Sbjct: 242 IIRDNLDSFDILMASGSTSAGFLDMLYRVIEKVGGSILFHGINMRPGKPTFFGRIGEKLF 301 Query: 294 I-MSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352 I M G+P++ + V ++ K + ++ + P + + ++ R+G Sbjct: 302 IGMPGFPLSSAVILNYIVIPSIRKAISGDFERPRVVKVPVKIAPDHMQETVYPAIITRNG 361 Query: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 A I SG IS + ++ ++ +P D + G+ V Sbjct: 362 YAFPI-MGNSGSISRIRFADGFIAIPGDLKYVDPGDNV 398 >sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1075033|pir||B64124 molybdopterin biosynthesis protein moeA - Haemophilus influenzae (strain Rd KW20) >gi|1574287|gb|AAC23098.1| (U32823) molybdopterin biosynthesis protein (moeA) [Haemophilus influenzae Rd] Length = 404 Score = 200 bits (503), Expect = 3e-50 Identities = 135/398 (33%), Positives = 214/398 (52%), Gaps = 23/398 (5%) Query: 11 EALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQA 70 +A + +L + E++ L EA NR+ A+DIIS +VP FD SA+DGYAVR D Q+ Sbjct: 6 QARSKMLEQLPFPTQTEYLNLQEAANRICAEDIISPINVPSFDNSAMDGYAVRLSDLQQS 65 Query: 71 REYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-REGEKIY 129 + L V + AG + + S +A++++TGA IPEG +AVIMQE V E I Sbjct: 66 -----LTLSVAGKSFAGNPFQEEWPSKSAVRIMTGAMIPEGTDAVIMQEQVTLNEDGTIT 120 Query: 130 VLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIIT 189 P QN+ GEDVKKG+V+L +G L P L +L +LGI V R+ +VG++ T Sbjct: 121 FSELPKPNQNIRRIGEDVKKGDVVLEQGAQLTPVSLPLLASLGIAEVKCYRQLKVGVLST 180 Query: 190 GSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRE 249 G ELVE + G+I +TN +K L+ K E I G++PD E + +A A+ + Sbjct: 181 GDELVEVGK--PLQSGQIYDTNRFTVKLLLEKLHCEVIDLGLLPDNEAEFEKAFIAAQSQ 238 Query: 250 CDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYG--ERVFI--MSGYPVA 301 DLV+ +GG + G+ D+ ++ + F IKPG+P +G E + + G PV+ Sbjct: 239 ADLVITSGGVSVGEADFTKAVLEKVGQVNFWKIAIKPGKPFAFGKLENAWFCGLPGNPVS 298 Query: 302 VFAQFHLFVKHALAKMVGARDYE--VKLRAILEDDVPSQLGRHEFVKVLY---RDGKAKV 356 F+ V+ +AK+ G + ++ AI ++ +GR +F + Y G+ +V Sbjct: 299 ALVTFYQLVQPLIAKLQGQKQWKKPPHFSAIATMNLKKAVGRLDFQRGFYYINEQGQIEV 358 Query: 357 --IKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWI 392 + +GS + S+ V+SN ++ + ++ GE V I Sbjct: 359 QSVGFQGSHLFSAFVKSNCFIVLEQERGNVSAGETVTI 396 >pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9656032|gb|AAF94681.1| (AE004231) molybdopterin biosynthesis MoeA protein [Vibrio cholerae] Length = 606 Score = 192 bits (484), Expect = 4e-48 Identities = 125/392 (31%), Positives = 212/392 (53%), Gaps = 23/392 (5%) Query: 16 LLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSP 75 +L+ ++ + + E V + E RVLA+++ S +VP + SA+DGYA+R++D + Y Sbjct: 216 ILSLISPLAETESVAIQECYQRVLAREVFSPNNVPAYRNSAMDGYALRSDD-LERDSY-- 272 Query: 76 IELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKI-YVLRPV 134 +V+ EV AG V G A+K++TGA +P GA+ V+M+E + GE + + + Sbjct: 273 ---RVVAEVLAGSHYPKTVERGEAVKIMTGAPMPLGADTVVMREQATQNGELVSFAGAKI 329 Query: 135 APGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELV 194 GQNV GED+ +G+ + G + ++ ML +LG R +V I TG E V Sbjct: 330 KAGQNVRQAGEDLAQGQAVFSIGQRVLSPEMGMLASLGFAHADAFRSLKVAIFSTGDE-V 388 Query: 195 EEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVL 254 + P D E I ++N L L+ + + I G+I D+E K+ + +++A ++ D+V+ Sbjct: 389 QAPGGD-IEPNSIFDSNRFTLTGLLKQLGCQVIDLGIIEDDEAKMMQVLEQAAKQADVVI 447 Query: 255 VTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQF 306 +GG + GD D+ ++ L F ++PGRP+ +G+ F + G PVAV F Sbjct: 448 TSGGVSVGDADFIKSALEKLGQIDFWRINMRPGRPLAFGQIAGKPFFGLPGNPVAVMVSF 507 Query: 307 HLFVKHALAKMVGARDYE-VKLRAILEDDVPSQLGRHEFVKVLYRDG-----KAKVIKKK 360 FV+ AL KM G + ++ +K+ AI +D+ S+ GR EF + +Y + K+ Sbjct: 508 INFVEPALRKMQGEQGWQPLKVNAIALEDLRSRQGRTEFSRGVYAFNTQGQLTVRTTGKQ 567 Query: 361 GSGIISSLVESNAYLEVPEDSEGYRRGEEVWI 392 GSGI+ S+ E+N +E+ + + GE V I Sbjct: 568 GSGILRSMSEANCLIEIAPAIDTVKVGESVTI 599 >sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1002858|gb|AAC44505.1| (U34309) moeA gene product [Anabaena sp.] Length = 436 Score = 192 bits (483), Expect = 6e-48 Identities = 133/419 (31%), Positives = 213/419 (50%), Gaps = 34/419 (8%) Query: 4 KKLMPY------REALTLLLNDVTEI---QDVEHVPLDEALNRVLAQDIISEFDVPPFDR 54 K L PY R+ ++ N V ++ QD E V L A R+LA + S D P +D Sbjct: 17 KPLHPYTPMPSVRDTANIIFNLVPKLDSQQDTEIVDLWAANGRILATPVNSTLDFPHWDN 76 Query: 55 SAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANA 114 SA+DGYAVR ED + P+ L+V+ E+PAG PK + G A ++ TGA +P G + Sbjct: 77 SAMDGYAVRYEDVHNSNAEQPVSLEVVAEIPAGYQPKFTLQPGQAARIFTGAVMPSGGDT 136 Query: 115 VIMQEMVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIK 174 V+MQE ++E ++++L PG+ V K + G +L T L ++A+L A Sbjct: 137 VVMQEKTRQENNRVFILTTPKPGEFVRLKAAYYQAGTQLLPANTQLNAAEIAILAASQCP 196 Query: 175 SVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPD 234 V V R+PRV I TG ELV + + G+IV++N L +LV + EPIL+G++ D Sbjct: 197 QVKVYRRPRVAIFSTGDELV--TLDQPLQPGQIVDSNQYALAALVKQNGAEPILFGIVKD 254 Query: 235 EEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFV-----KLLFHGTTIKPGRPIGYG 289 + E I KA D+V+ +GG + GD DY + + K+ ++PG+P+ Sbjct: 255 NPTALGETISKAIANADIVISSGGVSVGDYDYVDQILASLGAKIHIRSVEMRPGKPLTVA 314 Query: 290 ------ERVFI-MSGYPVAVFAQFHLFVKHALAKMVG-ARDYE---VKLRAILEDDVPSQ 338 +++ + G P AV F FV+ + K+ G A+ +E VK+R+ D++ S Sbjct: 315 TFPTPPAPIYLGLPGNPAAVLVTFWRFVQPVIRKLGGLAKGWEPVFVKVRS--HDELHSD 372 Query: 339 LGRHEFV--KVLYRDGKAKVIKKKG---SGIISSLVESNAYLEVPEDSEGYRRGEEVWI 392 R ++ + DG + K G SG + +L ++NA +P G++V + Sbjct: 373 GKRETYIWGSLHLVDGLYEFHKAGGSHSSGNLINLAQTNALAVLPLGETFISSGKDVLV 431 >pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658029|gb|AAF96518.1| (AE004391) molybdopterin biosynthesis MoeA protein [Vibrio cholerae] Length = 435 Score = 186 bits (467), Expect = 4e-46 Identities = 126/406 (31%), Positives = 208/406 (51%), Gaps = 24/406 (5%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 LMP +AL +L+ + +Q +PL EAL VLA+ I+S VPPFD SA+DGYAVR Sbjct: 33 LMPIEDALKKMLSRIQPVQTTLRLPLPEALGYVLAEAILSPIHVPPFDNSAMDGYAVRRA 92 Query: 66 DTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM--VKR 123 + Q + L V + AG+ T ++++TGA+IP G +AVIMQE + Sbjct: 93 ELAQQK-----PLPVAGKSFAGQPFTADWPPMTCVRIMTGAQIPAGCDAVIMQEQATITE 147 Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183 EG ++ V N+ G+D+++ +V+L +G L +D+ M+ LGI V V RKP+ Sbjct: 148 EG-VVFCQHEVKLNDNIRPTGDDIRQNDVVLERGARLTARDIPMIATLGISHVTVYRKPK 206 Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243 V TG EL +P + + G+I ++N +K L+ F E I G++PD ++ Sbjct: 207 VAFFSTGDEL--KPLGEPLQAGQIYDSNRYGIKPLIENFGCEAIDLGIVPDCPATLKATF 264 Query: 244 KKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYG---ERVFI-M 295 ++A+ D+V+ +GG + G+ DY ++ L F IKPG+P +G + F + Sbjct: 265 EQAQSLADVVVTSGGVSVGEADYTKDILEELGEIGFWKLAIKPGKPFAFGALQDAWFCGL 324 Query: 296 SGYPVAVFAQFHLFVKHALAKMVGARDYEV--KLRAILEDDVPSQLGRHEFVKVLYRDGK 353 G PV+ ++ V+ LAK+ G ++ + AI GR +F + +YR Sbjct: 325 PGNPVSAVLTMYVLVQPMLAKLAGHSAWQAPESIPAITRSPFKKAPGRTDFQRGIYRIEN 384 Query: 354 AKVIKK----KGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 + + + + SG S+ +N ++ + + GE V I L+ Sbjct: 385 GQFVVESTGNQSSGAFRSMSLANCFVVLERERGRVEVGETVQIQLF 430 >sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|78705|pir||A32352 molybdopterin biosynthesis protein moeA - Escherichia coli >gi|145539|gb|AAA23579.1| (M21151) chlE protein [Escherichia coli] >gi|1651376|dbj|BAA35515.1| (D90720) Molybdopterin biosynthesis MoeA protein. [Escherichia coli] >gi|1651379|dbj|BAA35522.1| (D90721) Molybdopterin biosynthesis MoeA protein. [Escherichia coli] >gi|1787049|gb|AAC73914.1| (AE000185) molybdopterin biosynthesis [Escherichia coli K12] Length = 411 Score = 185 bits (464), Expect = 1e-45 Identities = 134/406 (33%), Positives = 206/406 (50%), Gaps = 23/406 (5%) Query: 1 MEFKK-LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDG 59 MEF LM AL +L+ VT + E +PL + R+LA D++S DVP FD SA+DG Sbjct: 1 MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDG 60 Query: 60 YAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQE 119 YAVR D + L V + AG+ + +GT I+++TGA +PEG AV+MQE Sbjct: 61 YAVRLADIASGQP-----LPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQE 115 Query: 120 MVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVK 179 ++ + V GQN+ +GED+ G V+ GT L +L ++ +LGI VPV Sbjct: 116 QTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVI 175 Query: 180 RKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKI 239 RK RV + TG EL + P + +G+I +TN + + ++ + E I G+I D+ + Sbjct: 176 RKVRVALFSTGDEL-QLPGQ-PLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHAL 233 Query: 240 REAIKKAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGYGER---- 291 R A +A + D+V+ +GG + G+ DY + ++ F IKPG+P +G+ Sbjct: 234 RAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSW 293 Query: 292 VFIMSGYPVAVFAQFHLFVKHALAKMVG--ARDYEVKLRAILEDDVPSQLGRHEFVK-VL 348 + G PV+ F+ V+ LAK+ G A + R + GR +F + VL Sbjct: 294 FCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVL 353 Query: 349 YR--DGKAKVIK--KKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 R DG+ +V +GS I SS N ++ + D GE V Sbjct: 354 QRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWV 399 >emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri] Length = 408 Score = 182 bits (456), Expect = 8e-45 Identities = 109/296 (36%), Positives = 165/296 (54%), Gaps = 13/296 (4%) Query: 33 EALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKM 92 E RVLA+D+ +E PPF RSA+DGYAVR+ED LKV+ E GE + Sbjct: 42 ELSGRVLAEDVRAERPSPPFTRSAMDGYAVRSEDAEPGAR-----LKVVGESRIGEGTDV 96 Query: 93 KVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEV 152 KV G A+ V TGA +PEGA+AVI E V+R+G++I V V PG N+ G V++GEV Sbjct: 97 KVGPGEAVYVDTGAPVPEGADAVIPVEFVERDGDEIIVEEGVDPGDNLDPAGCYVEEGEV 156 Query: 153 ILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNS 212 + R G ++ P D+ ++ G++ V V R RV I++TG+ELV PSE E + Sbjct: 157 LYRSGHLVEPVDVGVMLEHGVEEVDVHRPLRVSIVVTGNELVHRPSELESETQVVDCIGP 216 Query: 213 IMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK 272 ++ L + E + ++ D+ +IRE ++ D+VL+TGGS+ G++D+ + Sbjct: 217 VLTAELENMGCVEVVGTSLVKDDPGEIRETVEDYADRSDVVLITGGSSVGERDHVKDILD 276 Query: 273 LLF----HGTTIKPGRPIGYGER----VFIMSGYPVAVFAQFHLFVKHALAKMVGA 320 F HG +PGRP G R F + G+P + ++ F ++V +L + GA Sbjct: 277 DTFDAFIHGIRARPGRPFGIAAREGTVAFTLPGWPTSCYSTFRVWVVPSLLVLAGA 332 >emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [Streptomyces coelicolor A3(2)] Length = 424 Score = 180 bits (452), Expect = 2e-44 Identities = 121/401 (30%), Positives = 197/401 (48%), Gaps = 41/401 (10%) Query: 33 EALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKM 92 +A VL DI +PPFD S++DGYAVR D A E P L+V+ +V AG++ + Sbjct: 24 DAQGCVLVDDITVPLSLPPFDNSSMDGYAVRVTDVAGASEEFPAVLEVVGDVAAGQTDPI 83 Query: 93 KVTSGTAIKVLTGAKIPEGANAVIMQE-----------------MVKREGEK--IYVLRP 133 V G A +++TGA +P GA AV+ E + EG + + V RP Sbjct: 84 AVGPGQAARIMTGAPLPPGAEAVVPVEWTDGGSGEGPVAGMRARSLAPEGAEGHVQVYRP 143 Query: 134 VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSEL 193 +V KG DV+ G+ L GT+L P + +L A+G +V V+ +PRV ++ TGSEL Sbjct: 144 AEERAHVRAKGSDVRSGDRALAAGTVLGPPQIGLLAAIGRGTVRVRPRPRVVVLSTGSEL 203 Query: 194 VEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLV 253 V+ ++ G+I ++NS L + G + D+ + +R I+ DL+ Sbjct: 204 VQ--PDEQLAPGQIYDSNSFALTAAARDAGAIAYRVGAVADDAETLRATIEDQLVRADLM 261 Query: 254 LVTGGSAFGDKDYAHRFVKLL-----------FHGTTIKPGRPIGYGE------RVFIMS 296 + TGG + G D + + F ++PG+P G+G + + Sbjct: 262 VTTGGVSVGAYDVVKEALAHVGDEDEPGGGVDFRKLAMQPGKPQGFGSVGPDHTPLLALP 321 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARD-YEVKLRAILEDD--VPSQLGRHEFVKVLYRDGK 353 G PV+ + F LFV+ A+ ++G D + + A L D + S GR +F++ + G Sbjct: 322 GNPVSSYVSFELFVRPAIRTLMGLPDVHRPTVTASLAADKALTSPKGRRQFLRGSHAGGS 381 Query: 354 AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITL 394 + GS ++++L ++NA + VPED+E G EV + L Sbjct: 382 VTPVGGSGSHLVAALAQANALIVVPEDTESVEPGTEVEVVL 422 >pir||G70829 probable molybdenum cofactor biosynthesis protein - Mycobacterium tuberculosis (strain H37RV) >gi|2909513|emb|CAA17395.1| (AL021932) moaA3 [Mycobacterium tuberculosis] Length = 405 Score = 177 bits (445), Expect = 2e-43 Identities = 113/369 (30%), Positives = 180/369 (48%), Gaps = 19/369 (5%) Query: 29 VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88 VPL +A VL D+++ +P FD SA+DGYAVRAEDT A +P+ L V E++PAG Sbjct: 23 VPLTQAQGLVLGGDVVAPLSLPVFDNSAMDGYAVRAEDTSGATPQNPVMLPVAEDIPAGR 82 Query: 89 SPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGEDVK 148 + + + TA +++TGA +P GA A++ E + + + + PG+++ GEDV Sbjct: 83 ADMLTLQPVTAHRIMTGAPVPTGATAIVPVEATDGGVDSVAIRQQATPGKHIRRSGEDVA 142 Query: 149 KGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIV 208 G +L G I+ P L + ALG+ +PV + RV +I TGSEL + + G+I Sbjct: 143 AGTTVLHNGQIVTPAVLGLAAALGLAELPVLPRQRVLVISTGSELASPGT--PLQPGQIY 200 Query: 209 ETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGG---------- 258 E+NSIML + V + D+ + + + + DL++ +GG Sbjct: 201 ESNSIMLAAAVRDAGAAVVATATAGDDVAQFGAILDRYAVDADLIITSGGVSAGAYEVVK 260 Query: 259 SAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQFHLFVKHAL 314 AFG DY + F ++PG P G G + + G PV+ F +F++ L Sbjct: 261 DAFGSADYRGGDHGVEFVKVAMQPGMPQGVGRVAGTPIVTLPGNPVSALVSFEVFIRPPL 320 Query: 315 AKMVGARD-YEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIK--KKGSGIISSLVES 371 +G D Y A+L + S G+ +F + + VI S + L + Sbjct: 321 RMAMGLPDPYRPHRSAVLTASLTSPRGKRQFRRAILDHQAGTVISYGPPASHHLRWLASA 380 Query: 372 NAYLEVPED 380 N L++PED Sbjct: 381 NGLLDIPED 389 >gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis protein; MoeA2 [Halobacterium sp. NRC-1] Length = 571 Score = 176 bits (443), Expect = 3e-43 Identities = 121/354 (34%), Positives = 180/354 (50%), Gaps = 15/354 (4%) Query: 57 VDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVI 116 +DGYAVRA DTF A E P L V V AGE P ++VT+G A+ V TGA +P GA+AV+ Sbjct: 1 MDGYAVRAADTFGASEADPARLSVAGTVHAGEEPAVEVTAGRAVVVSTGAVMPPGADAVV 60 Query: 117 MQEMVKRE--GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIK 174 E G+ + V VAPG V G D+ G + GT L +++ +L ALG+ Sbjct: 61 KVEATTEADGGDAVDVRTSVAPGTAVMLAGADIAAGSRAIGPGTKLTAREIGVLSALGVG 120 Query: 175 SVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPD 234 SV V+ P VGII TG ELV G+I + NS + + V GEP++Y D Sbjct: 121 SVRVRGAPTVGIISTGDELVRPGDPLDSAAGQIHDVNSHTIAAAVEAAGGEPVVYPHAGD 180 Query: 235 EEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYGE 290 + ++ + ++ +CDLVL +G ++ D +R + LL HG +KPG+P+ GE Sbjct: 181 DYAEMERLLVESAADCDLVLSSGSTSASAVDVIYRVAEERGDLLLHGVAVKPGKPMLVGE 240 Query: 291 ---RVFI-MSGYPVAVFAQFHLFVKHALAKMVGARDYE-VKLRAILEDDVPSQLGRHEFV 345 ++ + GYPV+ F +FV + + G E + + S GR + Sbjct: 241 IEGTAYVGLPGYPVSALTIFRVFVAPVVREAAGRGQPEPTVVTGEMARQERSAEGRRRLL 300 Query: 346 KV-LYRDGKAKVI---KKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 V L DG + KGSG +SLV+++ + VP D+ G+ V + L+ Sbjct: 301 PVGLVEDGAGDRLVYPVDKGSGATTSLVDADGTVTVPADTAYVAAGDSVDVALF 354 >pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949132|gb|AAG06416.1|AE004728_2 (AE004728) molybdenum cofactor biosynthesis protein A2 [Pseudomonas aeruginosa] Length = 405 Score = 174 bits (437), Expect = 1e-42 Identities = 122/391 (31%), Positives = 208/391 (52%), Gaps = 32/391 (8%) Query: 6 LMPYREALTLLLNDV--TEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVR 63 LMP AL LL T I E VPL++A RVLA D+++ D+PP+ SA+DGYA+R Sbjct: 10 LMPVETALERLLELAAQTPIDTCEQVPLEQAGGRVLAVDLLAGLDLPPWPNSAMDGYALR 69 Query: 64 AEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR 123 D ++ L V +++ AG++PK + +GT ++ TGA +PEGA+ V MQE + Sbjct: 70 LAD------WNGEPLPVSQKIFAGQAPK-PLQAGTCARIFTGAPLPEGADLVEMQENAEA 122 Query: 124 -EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182 + ++ +P+ GQ+V +G+++++G+++L GT LR +L + +LG ++ V+RKP Sbjct: 123 LDDGRVRFTQPLRVGQHVRPRGQEIRQGDLVLPAGTRLRSIELGLAASLGYAALEVRRKP 182 Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242 RV ++ TG ELVE + + G+I +N +LK + + + + G++PD+ + RE Sbjct: 183 RVALLSTGDELVE--AGQPLQAGQIYNSNRPLLKDWLQRLGCDVLDAGILPDDLARTRER 240 Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYGE----RVFI 294 + DL+L TGG + G+ D+ ++ L IKPG+P+ G+ V Sbjct: 241 L-AGLAGVDLILSTGGVSVGEADFLGMALREAGELTLWKLAIKPGKPLTVGQFQGIPVIG 299 Query: 295 MSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLG------RHEFVKVL 348 + G P + F L + L + +G V A L +VP+ R E+++ Sbjct: 300 LPGNPASTLVTFALLARPYLLRRLG-----VAQVAPLRVEVPAGFAWTKAGQRREYLRGR 354 Query: 349 YRDGKAKVIKKKGSGIISSLVESNAYLEVPE 379 G+A + + SG++ S + +EV E Sbjct: 355 LEQGRAVLYPNQSSGVLRSASWAEGLVEVRE 385 >pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968943|emb|CAB73939.1| (AL139078) putative molybdopterin biosynthesis protein [Campylobacter jejuni] Length = 396 Score = 173 bits (434), Expect = 3e-42 Identities = 114/391 (29%), Positives = 206/391 (52%), Gaps = 24/391 (6%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 LM Y E+L +L + + + +E + L E L R+LAQDI + + P F SA+DGYA++ E Sbjct: 2 LMSYEESLKILHSHIKTYEKIEKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFE 61 Query: 66 DTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREG 125 D + LK++ PAG P+ V +GT +K TG+ + EG++ ++ E ++ E Sbjct: 62 DQDKP-------LKILGLTPAGTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENIRIEN 114 Query: 126 EKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVG 185 +++ + V V GE+ KK E++L+KGT L ++A+L LG + V KP VG Sbjct: 115 NTLFIEKKVPQAFAVRAVGENYKKDEILLKKGTRLNYSEIALLAELGFFHISVFIKPIVG 174 Query: 186 IIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKK 245 ++ +GSE +++ E +I +N I + +L + ++ ++ D+E ++ Sbjct: 175 VLSSGSE-IKDLGEALENPAQIRSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLES 233 Query: 246 AKRECDLVLVTGGSAFGDKDYAHRFVK---LLFHGTTIKPGRPIGYGER----VFIMSGY 298 A + CD+++ TGG + GD D+ + +K ++ IKPGR I + + + G+ Sbjct: 234 ALQSCDILVTTGGVSMGDFDFLKKAIKEYEIIIDKADIKPGRHIKIAKANEKFIIALPGF 293 Query: 299 PVAVFAQFHLFVKHAL-AKMVGARDYEVKLRAILEDDVPSQLGRHEFV--KVLYRDGKAK 355 P + F+L+ + L + ++ +DY K A L+ + EFV + +++G+ Sbjct: 294 PYSAMVMFNLYTREILNSWLLQPKDYICK--AFLQGSYKKKTPYLEFVACNIEFKNGRIL 351 Query: 356 VI---KKKG-SGIISSLVESNAYLEVPEDSE 382 KK+G S II++L A + VP++ E Sbjct: 352 ANLEGKKEGSSAIINNLNNKAALMVVPKECE 382 >sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1256834|gb|AAA96529.1| (U53178) moeA gene product [Salmonella typhimurium] Length = 412 Score = 168 bits (422), Expect = 8e-41 Identities = 133/407 (32%), Positives = 201/407 (48%), Gaps = 26/407 (6%) Query: 1 MEFKK-LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDG 59 MEF LMP ALT +L+ +T + VE +PL R+LA DI+S DVP FD SA+DG Sbjct: 3 MEFSAGLMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDG 62 Query: 60 YAVRAEDTFQAREYSPIELKVIEEVP-AGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQ 118 YAVR D A + P+ K P GE P +GT I+++TGA +P G AV+MQ Sbjct: 63 YAVRVAD-LSADKPLPVAGKAFAGQPYQGEWP-----AGTCIRIMTGAPVPAGCEAVVMQ 116 Query: 119 EMVKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPV 178 E ++ + V GQN+ +GED+++ V+ GT L +L +L +LGI V Sbjct: 117 EQTEQTDDGERFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAELPVLASLGIADAQV 176 Query: 179 KRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKF-FGEPILYGVIPDEED 237 RK RV + TG EL + P + E +I +TN + + ++ + + E I G+IPD+ Sbjct: 177 VRKVRVALFSTGDEL-QLPGQ-PLEADQIYDTNRLTIHLMLQQLGWREVINLGIIPDDPG 234 Query: 238 KIREAIKKAKRECDLVL---VTGGSAFGDKDYAHRFVKLLFHGTTIKPGRPIGYGER--- 291 K+R I A + D+V+ V+ G A K ++ F IKPG+P +G+ Sbjct: 235 KLRGFI-DADSQADVVISSRVSEGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNS 293 Query: 292 -VFIMSGYPVAVFAQFHLFVKHALAKMVG--ARDYEVKLRAILEDDVPSQLGRHEFVK-V 347 + G PV+ F+ V+ LAK+ G A + R + GR +F + + Sbjct: 294 WFCGLPGNPVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVRTASRLKKTPGRLDFQRGI 353 Query: 348 LYRDGKAKV----IKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 L R ++ +GS I SS N ++ + + GE V Sbjct: 354 LQRSANGELEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWV 400 >gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulfolobus solfataricus] Length = 550 Score = 167 bits (418), Expect = 2e-40 Identities = 113/334 (33%), Positives = 180/334 (53%), Gaps = 19/334 (5%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 L EA+ + L+ + I V + ++ V A+D+ S D PPF RS VDGYA+++ Sbjct: 14 LYSIEEAIRVYLSSLNFIPKTVEVEVKDSFGYVSAEDLNSPIDYPPFSRSNVDGYALKSS 73 Query: 66 DTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR-E 124 T P ELKVI+ + GE ++ + A++V TGA IP GA+AVI E VK Sbjct: 74 CT-------PGELKVIDRIEIGEFKEVHINECVAVEVDTGAIIPMGADAVIKVEDVKIIS 126 Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184 G I V + + GQN+ + G D+ K +ILRKG ++ + + +L +LGI V V K +V Sbjct: 127 GNLIKVDKKMTFGQNIGWIGSDIPKNSIILRKGEVISHEKIGLLASLGISKVKVYEKLKV 186 Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244 +I TG ELVE ++ GKI E+N L S + + + + + ++ D+ + I+ IK Sbjct: 187 YLIATGDELVE--PGNSLSPGKIYESNLHYLYSKLKQNY-QIVGLSLLRDDIESIKNEIK 243 Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFVK----LLFHGTTIKPGRPIGYG----ERVFIMS 296 +A D++++TGG++ G+KD+ HR +K ++ HG IKPG+P G + V + Sbjct: 244 RAISLADVLILTGGTSAGEKDFVHRAIKELGSIIVHGIKIKPGKPTILGVVDNKPVIGLP 303 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI 330 G V+ F + L + +R V+L I Sbjct: 304 GNIVSSVVVFDTVISEILRNLYPSRKEIVELGKI 337 >sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN LINKER PROTEIN) >gi|111656|pir||JH0681 gephyrin - rat >gi|56312|emb|CAA47009.1| (X66366) Gephyrin [Rattus norvegicus] Length = 736 Score = 164 bits (411), Expect = 2e-39 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%) Query: 19 DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78 ++T + E + + + RVLAQD+ ++ ++PPF S DGYAVRA D P + Sbjct: 335 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 387 Query: 79 KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130 +I E AGE P V G ++V TGA IP GA+AV+ E + RE + ++ + Sbjct: 388 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 447 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 L PGQ++ G D+K+GE +L KGT + P ++ +L +G+ V V + P V ++ TG Sbjct: 448 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 507 Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250 +EL+ ED GKI ++N L + + + I G++ D D + A+ + Sbjct: 508 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 565 Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296 D+++ +GG + G+KDY + + + H +KPG P G + +F + Sbjct: 566 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 625 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353 G PV+ +LFV AL KM G D +K R + + + H + + Sbjct: 626 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 685 Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390 + G+ + S L+ +N L +P +E Y +GE V Sbjct: 686 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 728 >dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens] Length = 768 Score = 164 bits (411), Expect = 2e-39 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%) Query: 19 DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78 ++T + E + + + RVLAQD+ ++ ++PPF S DGYAVRA D P + Sbjct: 367 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 419 Query: 79 KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130 +I E AGE P V G ++V TGA IP GA+AV+ E + RE + ++ + Sbjct: 420 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 479 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 L PGQ++ G D+K+GE +L KGT + P ++ +L +G+ V V + P V ++ TG Sbjct: 480 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 539 Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250 +EL+ ED GKI ++N L + + + I G++ D D + A+ + Sbjct: 540 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 597 Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296 D+++ +GG + G+KDY + + + H +KPG P G + +F + Sbjct: 598 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 657 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353 G PV+ +LFV AL KM G D +K R + + + H + + Sbjct: 658 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 717 Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390 + G+ + S L+ +N L +P +E Y +GE V Sbjct: 718 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 760 >gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens] Length = 736 Score = 164 bits (411), Expect = 2e-39 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%) Query: 19 DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78 ++T + E + + + RVLAQD+ ++ ++PPF S DGYAVRA D P + Sbjct: 335 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 387 Query: 79 KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130 +I E AGE P V G ++V TGA IP GA+AV+ E + RE + ++ + Sbjct: 388 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 447 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 L PGQ++ G D+K+GE +L KGT + P ++ +L +G+ V V + P V ++ TG Sbjct: 448 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 507 Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250 +EL+ ED GKI ++N L + + + I G++ D D + A+ + Sbjct: 508 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 565 Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296 D+++ +GG + G+KDY + + + H +KPG P G + +F + Sbjct: 566 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 625 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353 G PV+ +LFV AL KM G D +K R + + + H + + Sbjct: 626 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 685 Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390 + G+ + S L+ +N L +P +E Y +GE V Sbjct: 686 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 728 >gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|CAC10537.1| (AJ272343) gephyrin [Homo sapiens] Length = 769 Score = 164 bits (411), Expect = 2e-39 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%) Query: 19 DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78 ++T + E + + + RVLAQD+ ++ ++PPF S DGYAVRA D P + Sbjct: 368 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 420 Query: 79 KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130 +I E AGE P V G ++V TGA IP GA+AV+ E + RE + ++ + Sbjct: 421 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 480 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 L PGQ++ G D+K+GE +L KGT + P ++ +L +G+ V V + P V ++ TG Sbjct: 481 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 540 Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250 +EL+ ED GKI ++N L + + + I G++ D D + A+ + Sbjct: 541 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 598 Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296 D+++ +GG + G+KDY + + + H +KPG P G + +F + Sbjct: 599 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 658 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353 G PV+ +LFV AL KM G D +K R + + + H + + Sbjct: 659 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 718 Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390 + G+ + S L+ +N L +P +E Y +GE V Sbjct: 719 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 761 >gi|11435181 gephyrin [Homo sapiens] Length = 419 Score = 164 bits (411), Expect = 2e-39 Identities = 118/403 (29%), Positives = 195/403 (48%), Gaps = 40/403 (9%) Query: 19 DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78 ++T + E + + + RVLAQD+ ++ ++PPF S DGYAVRA D P + Sbjct: 18 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 70 Query: 79 KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130 +I E AGE P V G ++V TGA IP GA+AV+ E + RE + ++ + Sbjct: 71 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 130 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 L PGQ++ G D+K+GE +L KGT + P ++ +L +G+ V V + P V ++ TG Sbjct: 131 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG 190 Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250 +EL+ ED GKI ++N L + + + I G++ D D + A+ + Sbjct: 191 NELLN--PEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRA 248 Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296 D+++ +GG + G+KDY + + + H +KPG P G + +F + Sbjct: 249 DVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 308 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353 G PV+ +LFV AL KM G D +K R + + + H + + Sbjct: 309 GNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 368 Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390 + G+ + S L+ +N L +P +E Y +GE V Sbjct: 369 LPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 411 >gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [Archaeoglobus fulgidus] >gi|7445252|pir||A69270 molybdenum cofactor biosynthesis protein (moeA-3) homolog - Archaeoglobus fulgidus >gi|2650482|gb|AAB91068.1| (AE001095) molybdenum cofactor biosynthesis protein (moeA-3) [Archaeoglobus fulgidus] Length = 400 Score = 162 bits (406), Expect = 6e-39 Identities = 122/394 (30%), Positives = 204/394 (50%), Gaps = 44/394 (11%) Query: 24 QDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEE 83 ++ E V +++AL+R LA+D+ + D+PPFD + +DGYA++ ED REY +++ E Sbjct: 28 RESEEVRVEDALDRELAEDVFAAKDMPPFDIATMDGYALKLEDG--VREY-----RIVGE 80 Query: 84 VPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFK 143 V AGE V G + + TGAK+P A+ V+ E+ + +G K+ + V G+ V K Sbjct: 81 VYAGEVEDRFVNRGECVYITTGAKMPVNADTVVKVEIAEVDGSKMRIREKVNRGKYVLKK 140 Query: 144 GEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFE 203 G +VKKG++IL T + PQ++A L + G++ V V R+ R + G E+ + Sbjct: 141 GSEVKKGDLILPAKTRIGPQEIAALISAGVERVRVFRRLRAAVFSNGDEI---------K 191 Query: 204 EGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGD 263 +G I ++NS M+ + + K E GV D+ +++RE ++K R+ D VL +GG + G+ Sbjct: 192 KGIIADSNSAMISAFLRKLGCEVHFLGVAGDDAEEVREMVEKGVRDYDAVLTSGGVSVGE 251 Query: 264 KDYAHRFVK----LLFHGTTIKPGRPIGYG----ERVFIMSGYPVAVFAQFHLFVKHALA 315 KDY + +K +L + +PG+P+ + VF + G P F L ++ A Sbjct: 252 KDYVVKALKEMGEVLIYKVRQRPGKPMVVAVVNEKPVFALPGKPAGCFTAM-LSLRRFFA 310 Query: 316 KMVGARDYEVKLRAILEDDV--PSQLGRHEFVKVLYRDGKA----------KVI--KKKG 361 G + + K+RA + DV P++ G F+ V RDG A +I +K Sbjct: 311 ---GDKPFP-KVRARIAGDVKLPTK-GFSYFLFVKLRDGYAIPAGFRHSHVSIIPYEKYE 365 Query: 362 SGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 ++S++ S R GEEV + LY Sbjct: 366 VSLVSAMARSAVSDGFVVTDRDLRAGEEVEVCLY 399 >pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950098|gb|AAG07301.1|AE004809_1 (AE004809) molybdenum cofactor biosynthetic protein A1 [Pseudomonas aeruginosa] Length = 407 Score = 160 bits (400), Expect = 3e-38 Identities = 113/371 (30%), Positives = 193/371 (51%), Gaps = 17/371 (4%) Query: 5 KLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64 +L P EAL LL E + L+ AL RVL +D+++ D+P +D SA+DGYA+ + Sbjct: 10 QLRPLDEALAELLARAPRPPACESLALERALGRVLGEDLLAPMDLPHWDNSAMDGYALCS 69 Query: 65 EDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124 D + S L V + AG++ M + G A ++ TGA +P GA+ V+ QE+ + Sbjct: 70 ADLPR----SGGSLTVGARIAAGDTRGMSLPLGQAARIFTGAPLPTGADCVVPQELCVVD 125 Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184 GE++ L PV+ GQ+V +GE++++G +LR G LRPQ+L +L +LG+ +V V+R+ R+ Sbjct: 126 GERVQ-LPPVSAGQHVRRRGEELRRGAPVLRAGQRLRPQELGLLASLGVATVSVRRRLRI 184 Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244 G++ +G EL EP + G+I N + +L+ E V+ DE R+A+ Sbjct: 185 GLLSSGDEL-REPGQTLL-AGQIYNANRYCIGALLRGLGFEVHDEEVLADELVASRDALS 242 Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGERV----FIMS 296 A E D ++ +GG + G++D+ R + L I+PG+P +G + Sbjct: 243 LAASEWDALVTSGGVSVGEEDHLKRAIAELGEVNLWRLAIQPGKPFAFGSVAGKPWLGLP 302 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI-LEDDVPSQLGRHEFVKV-LYRDGKA 354 G P A L + L + G D + A+ D P R ++++ L G+ Sbjct: 303 GNPAAALVTALLVARPFLLRQQGLFDVVPRPLALPAAFDWPQPRARRQYLRARLDERGRV 362 Query: 355 KVIKKKGSGII 365 ++ ++GS ++ Sbjct: 363 EIHPQQGSAML 373 >pir||T46858 molybdenum cofactor biosynthesis protein A [imported] - Rhodobacter sphaeroides >gi|4185549|gb|AAD09121.1| (AF108766) molybdenum cofactor biosynthesis protein A [Rhodobacter sphaeroides] Length = 394 Score = 157 bits (394), Expect = 2e-37 Identities = 119/372 (31%), Positives = 187/372 (49%), Gaps = 31/372 (8%) Query: 26 VEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVP 85 VE V L EA RV+A+ ++ D PPFD SA+DGYA+ + A V+ E Sbjct: 20 VERVALGEARGRVMARPALATRDQPPFDASAMDGYALIGDPPAGAT------FPVVGEAA 73 Query: 86 AGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGE 145 AG + + G A+++ TGA +PEGA V++QE V EG I + G ++ +G+ Sbjct: 74 AGHGYEGALRPGEAVRIFTGAPVPEGATRVVLQEDVTAEGGTIRLNAAATGGTHIRPRGQ 133 Query: 146 DVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELV---EEPSEDAF 202 D + G+ + + LRP DLA+L A+ I V V R+P V +I TG ELV E P D Sbjct: 134 DFRTGDSLSPRR--LRPNDLALLAAMNIPEVTVTRRPSVALIATGDELVMPGEVPRPD-- 189 Query: 203 EEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFG 262 +IV +NS LK+LV E L + D ED++R + A + DL++ GG++ G Sbjct: 190 ---QIVASNSFALKALVEAEGAEARLLPIARDTEDELRTVLDLAS-DADLIVTIGGASVG 245 Query: 263 DKDYAHRF-----VKLLFHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQFHLFVKHA 313 D D + ++ F+ ++PG+P+ G + + G PV+ HLF+ Sbjct: 246 DHDLVGKVAAGMGLERAFYKIAMRPGKPLMAGRLRGVPMLGLPGNPVSSIVCAHLFLLPM 305 Query: 314 LAKMVGARDYEVK-LRAILEDDVPSQLGRHEFV--KVLYRDGKAKV--IKKKGSGIISSL 368 L M+G LRA L +P+ R ++ ++ +DG ++ + S ++ L Sbjct: 306 LRAMLGLPPAPAPLLRAELAVALPANPTRAHYMRARLTRQDGLPRIEPFSSQDSALLRLL 365 Query: 369 VESNAYLEVPED 380 E++A L P D Sbjct: 366 AEADALLVRPVD 377 >emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes] Length = 410 Score = 157 bits (392), Expect = 3e-37 Identities = 122/405 (30%), Positives = 196/405 (48%), Gaps = 35/405 (8%) Query: 10 REALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQ 69 R+A++++L I V + L + ++LAQD+ + +P FD S +DGYAVR D Q Sbjct: 8 RKAISIMLEHANPIHRVHYTHLFDLTGKILAQDLFCQKALPAFDNSGMDGYAVRLADLGQ 67 Query: 70 AREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVI-MQEMVKREGEKI 128 + ++ + AGES + + G KV+TGA IP G AVI + ++ + Sbjct: 68 -------KTPILGTILAGESCSVGLHDGACYKVMTGAPIPLGTQAVIPFENATLKDDSTV 120 Query: 129 YVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIII 188 + G N+ GE+++ G +L+KG L +A+L + G +P R+G+ Sbjct: 121 LLPTDFKEGANIKIAGEELQVGAPLLQKGERLTHHHVALLASQGYSVLPTYAPLRIGVYS 180 Query: 189 TGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKR 248 +G+EL+ EP E A + +I +N+ ML S + F GV+PD + +REAI + Sbjct: 181 SGNELI-EPWESA-QSHQIYNSNASMLFSTLQNFGWRADYLGVLPDCLEGMREAI-RGFD 237 Query: 249 ECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRPIGYG----ERVFIMSGYP 299 D++L TGG + G+ D+ R ++ LFHG +KPGRP G + + G P Sbjct: 238 AYDVILTTGGVSQGEADFMERSLEEAGMTTLFHGIEVKPGRPTMMGILGKTTLLCLPGNP 297 Query: 300 VAVFAQFHLFVKHALAKMVGARDYEV-------KLRAILEDDVPSQ-LGR-HEFVKVLYR 350 ++ H L KM G R Y + K R IL+ + + LGR HE + Sbjct: 298 LSASINLHFLGIPMLKKMQGERRYHLEFVYAPNKERLILKGNRANMVLGRLHEGCFKATQ 357 Query: 351 DGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 +G K GSG+++ L SNA + + E G + + Y Sbjct: 358 EG------KYGSGMLTPLTTSNAIIFCDKGVENLEEGALIKVIPY 396 >pir||T44851 molybdopterin co-factor synthesis protein moeA [imported] - Arthrobacter nicotinovorans plasmid pAO1 >gi|4469094|emb|CAA71780.2| (Y10817) molybdopterin co-factor synthesis protein [Arthrobacter nicotinovorans] Length = 430 Score = 156 bits (391), Expect = 3e-37 Identities = 117/401 (29%), Positives = 195/401 (48%), Gaps = 22/401 (5%) Query: 2 EFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYA 61 E + + +R+A+ +L + VE +PL +A+ R LA+ I + ++PPF S +DGYA Sbjct: 29 EHRSVSVHRQAIRDVLFPLLTPPRVERIPLMQAMGRGLAETIHAPTNLPPFTNSQMDGYA 88 Query: 62 VRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMV 121 VR+ DT + L+V +PAG P + GTA +++TGA IP+GA+AV+ E Sbjct: 89 VRSRDTAGGQG----GLRVAAPIPAGAVP-APLVGGTAAQIMTGALIPDGADAVVPVERA 143 Query: 122 KREG------EKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKS 175 ++ L +A G + G D+ GE L GT+L P+ L +L ALGI Sbjct: 144 VPNHFPPPGLDRTVRLPEIAAGTYIRSAGSDIATGECALSAGTVLGPRQLGLLAALGITE 203 Query: 176 VPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDE 235 V V +K V + TG E++E + A GKI + N+ +L+S + + I G++ DE Sbjct: 204 VVVNQKLTVLLATTGDEVLEPGEKLAL--GKIYDANNTLLQSSMLQAGLNVIRAGIVKDE 261 Query: 236 EDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFV---KLLFHGTTIKPGRPIGYGE-- 290 + + ++ DL++ +GG + G + + + + F I+PG P G G Sbjct: 262 PGALSKLLRSHTAHVDLIVTSGGVSAGAYEPVRQAMIDHDVEFSHVAIQPGGPQGVGTFE 321 Query: 291 --RVFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKL--RAILEDDVPSQLGRHEFVK 346 V G PV+ F F +F++ L++M + L DV + Sbjct: 322 GIPVLAFPGNPVSCFVSFEMFLRPLLSEMFASAHTSTLLPRPPFASPDVTPKKAPGFRRG 381 Query: 347 VLYRDGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRG 387 VL DG ++ +GS ++ +L SN + +P + G +G Sbjct: 382 VLSADGTIRLEGGEGSHLLGALARSNVLVHIPRGNFGTGQG 422 >sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1480150|emb|CAA67944.1| (X99625) moeA [Synechococcus sp.] Length = 403 Score = 155 bits (388), Expect = 8e-37 Identities = 120/400 (30%), Positives = 196/400 (49%), Gaps = 18/400 (4%) Query: 6 LMPYREALTLLLNDVTEIQ-DVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64 ++ Y A+ LLL +V ++ +E VPL E +R+LA+D+ + D+P +D SA+DG+A+R+ Sbjct: 2 ILSYSAAIELLLAEVAQLPLAIERVPLLETGDRLLAKDLAAPCDLPHWDNSAMDGFALRS 61 Query: 65 EDTFQAREYSPIELKVIEEVPAGESPKMKVT-SGTAIKVLTGAKIPEGANAVIMQEMVKR 123 +D A P+ L V+ V AGE P + +G A V+TGA IP G + ++ E V + Sbjct: 62 QDVAAASPDRPVRLPVVGRVMAGEQPPLLANPTGVACAVMTGAPIPAGFDVIVKVEDVVQ 121 Query: 124 EGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPR 183 E I V P+ GQ + +GED+++G +L KG L P L + A+G+ +PV K Sbjct: 122 EENAIAVSTPIPAGQFIRRQGEDLRQGSPLLAKGQRLTPMALMLAAAVGMGELPVWSKLP 181 Query: 184 VGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAI 243 VG+I TG+E+V S+ E G+I ++ L + + E +PD+ ++ Sbjct: 182 VGLISTGTEVVPW-SQPTLELGQIRNSSQPFLIEQLQRLGCEVRAIAHVPDDPEQFAAIA 240 Query: 244 KKA-KRECDLVLVTGGSAFGDKDYAHRFVKLL-----FHGTTIKPGRPIGYG------ER 291 ++ + L+L TG + G D+ ++ L FH I+PG+P+ + Sbjct: 241 QQFWSQGVRLLLTTGAVSMGVADFVPAALERLGCQTIFHKVAIRPGKPLLFAIAPEHQGL 300 Query: 292 VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKV-LYR 350 V G PV+ F+K L M + L L + V G F + L Sbjct: 301 VLACPGNPVSTTVTAEFFLKPLL--MACRNEVRSPLWLPLAESVRKPEGLQCFWRSRLTP 358 Query: 351 DGKAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 +GK V ++ S + SLVES + +P + G V Sbjct: 359 EGKVWVDPQQSSAALKSLVESTHWAILPAGQDFLAAGTPV 398 >gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus] Length = 736 Score = 153 bits (383), Expect = 3e-36 Identities = 116/403 (28%), Positives = 190/403 (46%), Gaps = 40/403 (9%) Query: 19 DVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIEL 78 ++T + E + + + RVLAQD+ ++ ++PPF S DGYAVRA D P + Sbjct: 335 EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAAD-------GPGDR 387 Query: 79 KVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK--REGE------KIYV 130 +I E AGE P V G ++V TGA IP GA+AV+ E + RE + ++ + Sbjct: 388 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI 447 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 L PGQ++ G D+K+GE +L KGT P ++ +L +G+ V V + P V ++ TG Sbjct: 448 LVQARPGQDIRPIGHDIKRGECVLAKGTHTGPSEVGLLATVGVTEVEVNKFPVVAVMSTG 507 Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250 +EL+ ED GKI ++N L + + I G++ D D + A+ + Sbjct: 508 NELLN--PEDDVLPGKIRDSNRSTLLATIQAHGYPTINLGIVGDNPDDLLNALNERISRA 565 Query: 251 DLVLVTGGSAFGDKDYAHRFVKLLFHG------TTIKPGRPI--------GYGERVFIMS 296 D+++ +GG + G K Y + + + H +KPG P G + +F + Sbjct: 566 DVIITSGGVSMGGKYYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALP 625 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDYE---VKLRAILEDDVPSQLGRHEFVKVLYRDGK 353 G V+ +LFV AL KM G D +K R + + + H + + Sbjct: 626 GQSVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEP 685 Query: 354 AKVIKKKGSGIISSLV---ESNAYLEVPEDSEGY---RRGEEV 390 + G+ + S L+ +N L +P +E Y +GE V Sbjct: 686 HPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVV 728 >pir||A81359 probable molybdopterin biosynthesis protein Cj0857c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968303|emb|CAB73122.1| (AL139076) putative molybdopterin biosynthesis protein [Campylobacter jejuni] Length = 386 Score = 152 bits (381), Expect = 5e-36 Identities = 110/391 (28%), Positives = 200/391 (51%), Gaps = 26/391 (6%) Query: 11 EALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQA 70 E L L N ++ + + E + L++A +R+LA+D+ + ++P FD +A+DGYA D +A Sbjct: 6 ETLKDLENQISCLDESELISLEKAKDRILAKDLYARKNLPSFDNAALDGYAFNYTDINEA 65 Query: 71 REYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYV 130 L++ + AG+ V K++TGAK+P+ A+ ++M E E K+ + Sbjct: 66 -------LEIKGTIFAGDKNFYTVAKNECYKIMTGAKMPKNADTILMLEDECIEENKLII 118 Query: 131 LRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITG 190 + +KGE++KKGE++L+KGT L + +A+L + G+ + V RK R+GI +G Sbjct: 119 KKVPKQYNAYRYKGEELKKGEILLQKGTKLNDKHIALLASQGLYKIEVIRKIRIGIFSSG 178 Query: 191 SELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKREC 250 +EL +EP ++ EE I N++ L +++ G+I D+ +EA++ Sbjct: 179 NEL-KEPWQECDEE-SIYNANALPLLTMLQ----NASYLGIIKDDFKSTKEALENT--NF 230 Query: 251 DLVLVTGGSAFGDKDYAHRFV-----KLLFHGTTIKPGRPIGY---GER-VFIMSGYPVA 301 DL++ +GG++ G+ D+ + + LF G +P RP GE V I+ G P+A Sbjct: 231 DLLITSGGASVGEADFMEKALDELGFTPLFKGLKARPARPTKLYRKGENFVLILPGNPMA 290 Query: 302 VFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVI--KK 359 + +F K + + G D + + D+ + GR+ + G K Sbjct: 291 AYLSCFIFAKKIINLLSGNLDNPLTFYGKMGMDLKLKSGRNNLILGNLEKGIFTPFNENK 350 Query: 360 KGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 GSG+I L++S L E++ ++G+E+ Sbjct: 351 FGSGMILPLIKSEFLLISEENTGELKKGDEI 381 >sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MOLYBDENUM COFACTOR BIOSYNTHESIS ENZYME CNX1) >gi|1263314|gb|AAA97413.1| (L47323) molybdenum cofactor biosynthesis enzyme [Arabidopsis thaliana] >gi|4469123|emb|CAB38312.1| (AJ236870) molybdenum cofactor biosynthesis enzyme [Arabidopsis thaliana] Length = 670 Score = 142 bits (354), Expect = 8e-33 Identities = 118/423 (27%), Positives = 199/423 (46%), Gaps = 46/423 (10%) Query: 5 KLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64 +++P EAL ++ + V V L EAL +VLA+DI + +PP+ S DGYAV A Sbjct: 15 EMIPTEEALRIVFGVSKRLPPVI-VSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVA 73 Query: 65 EDTFQAREYSPIELKVIEEVPAG-ESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK- 122 D P E VI E AG + + VT GT V TG IP GA+AV+ E K Sbjct: 74 SD-------GPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPVGADAVVQVEDTKV 126 Query: 123 -----REGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVP 177 E +++ +L G ++ G D++K +L G + ++ +L G+ V Sbjct: 127 IGDVSTEAKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVK 186 Query: 178 VKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEED 237 V P V I+ TG ELV EP+ G+I ++N ML + V + + + G++ D+ Sbjct: 187 VYPMPIVAILSTGDELV-EPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRK 245 Query: 238 KIREAIKKA-KRECDLVLVTGGSAFGDKDYAHRFV----KLLFHGTTIKPGRPIGYGE-- 290 ++ + + +A D++L +GG + GD+D+ + K+ F +KPG+P+ + E Sbjct: 246 ELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIR 305 Query: 291 ------------RVFIMSGYPVAVFAQFHLFVKHALAKMVG-ARDYEVKLRAILEDDVPS 337 F + G PV+ F++FV + ++ G + +++R L++ + S Sbjct: 306 AKPTESMLGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKS 365 Query: 338 QLGRHEFVKVLYR----DGK------AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRG 387 R EF + + + DG A+ + S + S+ +NA LE+P G Sbjct: 366 DPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAG 425 Query: 388 EEV 390 V Sbjct: 426 SSV 428 >gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynthesis protein Cnx1 [Hordeum vulgare] Length = 659 Score = 138 bits (343), Expect = 1e-31 Identities = 112/398 (28%), Positives = 188/398 (47%), Gaps = 44/398 (11%) Query: 29 VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88 VPL +AL VLA+D + +PPF S DGYAV A D P E VI E AG+ Sbjct: 25 VPLLDALGLVLAEDARAPDPLPPFRASVKDGYAVVAAD-------GPGEYPVIAEARAGD 77 Query: 89 SPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR-----EGEK-IYVLRPVAPGQNVA 141 + VT GT V TG IP+GA+AV+ E ++ +G K + + V G ++ Sbjct: 78 DALGVVVTPGTVAYVTTGGPIPDGADAVVQVEDTEQVAAAPDGSKRVRISARVPEGHDIR 137 Query: 142 FKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDA 201 G D++K ++L+ G + P ++ +L +G+ +V R+P + + TG ELV EP+ Sbjct: 138 SVGCDIEKDSIVLKSGENIGPAEIGLLATVGVTTVKAYRRPTIAVFSTGDELV-EPATAT 196 Query: 202 FEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKA-KRECDLVLVTGGSA 260 G+I ++N ML + + + + G+ D E+ + E + A + D++L +GG + Sbjct: 197 LNRGQIRDSNRAMLLAAAIQQKCKVVDLGIAKDTEESLMEHMDAALHSDADIILTSGGVS 256 Query: 261 FGDKDYAH----RFVKLLFHGTTIKPGRPIGYGE-------------RVFIMSGYPVAVF 303 GD+D + K+ F +KPG+P+ + E F + G PV+ Sbjct: 257 MGDRDLVKPCLAKMGKIHFEKIRMKPGKPLTFAEITSNDTTKPSKTALAFGLPGNPVSCM 316 Query: 304 AQFHLFVKHALAKMVG-ARDYEVKLRAILEDDVPSQLGRHEFVKVLYR----DGK----- 353 F++FV A+ + G + + ++ + + + R EF + + R DG Sbjct: 317 VCFNVFVVPAIRLVSGWSNPHLQRVHVRISHPLRADPHRMEFHRAVIRWVLDDGSGRPGY 376 Query: 354 -AKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 A+ + S + S+ +NA LEV + G V Sbjct: 377 VAESTGHQASSRLLSMKSANALLEVQSSGQILAAGASV 414 >emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus] Length = 459 Score = 134 bits (335), Expect = 1e-30 Identities = 95/313 (30%), Positives = 154/313 (48%), Gaps = 22/313 (7%) Query: 20 VTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELK 79 V I D E + L +A R A + +E +P RSA+DG+A+R D A + L Sbjct: 70 VAPIGDSETLDLAQAAGRTSATSLRAEIALPRAARSAMDGFALRTADLAAA-----LTLP 124 Query: 80 VIEEVPAG-ESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQ 138 V V AG ++P + G A+++ TGA+IP GA+AV+ E V G ++ + APG Sbjct: 125 VAGTVAAGMQAPPLP--DGAALRIFTGAQIPAGADAVVPVEEVTETGAEVQLTAAPAPGS 182 Query: 139 NVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPS 198 ++ G + G ++LR+GT +R + +L + G+ V V R+PR+ I+ TG EL P Sbjct: 183 HIRAVGSEQPLGGLLLRRGTRIRAHHIGLLASNGVAEVAVVRRPRLAILSTGDEL-HRPG 241 Query: 199 EDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGG 258 +A + + N ML +L E +G++PD+ + + DL++ TG Sbjct: 242 AEAASRDTMPDVNRPMLIALAQGAGAEVDDHGILPDDAEATVAKFASLQGRYDLIVTTGA 301 Query: 259 SAFGDKDYAHRFVKLLFHG-------TTIKPGRPIGYGE----RVFIMSGYPVAVFAQFH 307 + G +D H L+ G +KPG+P+ +G V + G P + F Sbjct: 302 VSMGGRD--HLRPALIAAGGQIDGWKVALKPGKPVMFGRLGNAAVTGLPGNPFSAMVGFT 359 Query: 308 LFVKHALAKMVGA 320 LFV +A++ GA Sbjct: 360 LFVSAQIARLKGA 372 >pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiodurans (strain R1) >gi|6457741|gb|AAF09669.1|AE001871_1 (AE001871) molybdopterin biosynthesis MoeA [Deinococcus radiodurans] Length = 401 Score = 129 bits (321), Expect = 6e-29 Identities = 112/383 (29%), Positives = 183/383 (47%), Gaps = 30/383 (7%) Query: 29 VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88 +PL +AL L D+ + P SA+DG A R DT A +P+ L+V+ E AGE Sbjct: 31 LPLRKALGCTLGADLTALVSHPSATESALDGIACREADTLTASAGAPVALRVVGESRAGE 90 Query: 89 SPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGE--------KIYVLRPVAPGQNV 140 +V G +++ TGA +P G +A+ E + REGE + +LRP PG +V Sbjct: 91 PFAGEVGPGECVRIYTGAPLPPGTDAICPVEQL-REGEGTSAVERGTVELLRPARPG-DV 148 Query: 141 AFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSED 200 +G D GE ++ G L P LA+ ALG VPV+R RV ++ TG E+V P + Sbjct: 149 RPEGGDFHAGETVMSAGLRLTPARLALAAALGHAQVPVRRW-RVALLSTGDEVV-APGQ- 205 Query: 201 AFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSA 260 G++ ++N + L +L+ + E + G PD +RE + A DL+L +GG + Sbjct: 206 PLAPGQVYDSNRVGLAALLTEAGYEVLDLGHAPDSPAALRERL-GAAGGADLLLTSGGVS 264 Query: 261 FGDKDYAHRFV----KLLFHGTTIKPGRPIGYGE----RVFIMSGYPVAVFAQFHLFVKH 312 G D+ + ++ F ++PG P G VF + G PV+ F + V+ Sbjct: 265 MGRYDFMRDLLLGEGEITFWKVKMRPGGPALCGRWGGLPVFGLPGNPVSSLVVFQVIVRP 324 Query: 313 AL-AKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVES 371 L + + R + S + F + + + + ++GSG++ SL ++ Sbjct: 325 VLTGEPLPTR------QVTAATPFASLADKTAFWRGVLSGDEVRDYPRQGSGVLRSLSDA 378 Query: 372 NAYLEVPEDSEGYRRGEEVWITL 394 +A + VPE + GE V + L Sbjct: 379 DALVVVPE-GQNIAAGERVEVVL 400 >gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulfolobus solfataricus] Length = 389 Score = 128 bits (319), Expect = 1e-28 Identities = 107/395 (27%), Positives = 199/395 (50%), Gaps = 24/395 (6%) Query: 6 LMPYREALTLLLNDVTEIQDVE-HVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64 L+P EA ++ N E++ E +V + +AL ++ +DI++ +P SA+DGYA++ Sbjct: 3 LIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAIKY 62 Query: 65 EDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124 +D + + L+V+ ++ S ++ G V TG+ +P A++V+ E + E Sbjct: 63 DDYLKYGK-----LRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSRLE 117 Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184 GE + V G+N+ +GED+ G++I++KGT + P L +L I V V + Sbjct: 118 GEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKVS-DLKF 176 Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244 + G E+ S + ++ KI+++ S +L ++ K FG GV D+ + + E I+ Sbjct: 177 TVFANGDEIT---SFENPQKNKIIDSISPILIKILEK-FGSVKYMGVAKDDLNDVTEKIE 232 Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHG---TTIKPGRPIG--YGERVFIM 295 K+ D+++ GGS+ G+KDY + V ++LF G TIK G +G G+ + I+ Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRG-SVGRIQGKPILIL 291 Query: 296 SGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAK 355 G V+ FH F L+ ++G + ++ED + + V + G + Sbjct: 292 PGQVVSAITAFHEFGLSVLSNILGTNLKKFIKSTLVEDIYVNH--SMDSVYLFNVKGNSA 349 Query: 356 VIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 + G G+ S L ++N + + + Y++GEEV Sbjct: 350 FPLRWGVGLYSELAKANGF-AILKRGLTYKKGEEV 383 >emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sulfolobus solfataricus] Length = 389 Score = 128 bits (319), Expect = 1e-28 Identities = 107/395 (27%), Positives = 199/395 (50%), Gaps = 24/395 (6%) Query: 6 LMPYREALTLLLNDVTEIQDVE-HVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRA 64 L+P EA ++ N E++ E +V + +AL ++ +DI++ +P SA+DGYA++ Sbjct: 3 LIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAIKY 62 Query: 65 EDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124 +D + + L+V+ ++ S ++ G V TG+ +P A++V+ E + E Sbjct: 63 DDYLKYGK-----LRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSRLE 117 Query: 125 GEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRV 184 GE + V G+N+ +GED+ G++I++KGT + P L +L I V V + Sbjct: 118 GEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKVS-DLKF 176 Query: 185 GIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIK 244 + G E+ S + ++ KI+++ S +L ++ K FG GV D+ + + E I+ Sbjct: 177 TVFANGDEIT---SFENPQKNKIIDSISPILIKILEK-FGSVKYMGVAKDDLNDVTEKIE 232 Query: 245 KAKRECDLVLVTGGSAFGDKDYAHRFV----KLLFHG---TTIKPGRPIG--YGERVFIM 295 K+ D+++ GGS+ G+KDY + V ++LF G TIK G +G G+ + I+ Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRG-SVGRIQGKPILIL 291 Query: 296 SGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAK 355 G V+ FH F L+ ++G + ++ED + + V + G + Sbjct: 292 PGQVVSAITAFHEFGLSVLSNILGTNLKKFIKSTLVEDIYVNH--SMDSVYLFNVKGNSA 349 Query: 356 VIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEV 390 + G G+ S L ++N + + + Y++GEEV Sbjct: 350 FPLRWGVGLYSELAKANGF-AILKRGLTYKKGEEV 383 >pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elegans >gi|3875564|emb|CAA90060.1| (Z49887) contains similarity to Pfam domain: PF00994 (Molybdenum cofactor biosynthesis protein), Score=324.9, E-value=3.1e-94, N=1~cDNA EST yk255f8.5 comes from this gene~cDNA EST yk255f8.3 comes from this gene~cDNA EST yk561c5.3 comes from this gene~c> >gi|3879587|emb|CAA90069.1| (Z49889) contains similarity to Pfam domain: PF00994 (Molybdenum cofactor biosynthesis protein), Score=324.9, E-value=3.1e-94, N=1~cDNA EST yk255f8.5 comes from this gene~cDNA EST yk255f8.3 comes from this gene~cDNA EST yk561c5.3 comes from this gene~c> Length = 442 Score = 128 bits (318), Expect = 1e-28 Identities = 111/391 (28%), Positives = 182/391 (46%), Gaps = 48/391 (12%) Query: 26 VEHVPLD-EALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEV 84 VE + +D AL RV+A+++ S D+PP S DGYAV A D ++ + L Sbjct: 34 VESIQVDWSALGRVVAEEVKSSEDMPPVAASTKDGYAVIAHDGIGLKKMVGVSL------ 87 Query: 85 PAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-------REGEKIYVLRPVAPG 137 AG + V G +++ TG IPEGA+AVIM+E + E +I + V G Sbjct: 88 -AGNIYQGAVEIGKCVRISTGGIIPEGADAVIMREYTELVRQDQQSEETEIICKQAVQVG 146 Query: 138 QNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSE----- 192 +N+ G DV+ +VI+ + + +L A GI+++ V +KP V +I TGSE Sbjct: 147 ENIRLPGSDVRSSDVIVPFEAQIGSAEFGILNAFGIRTIKVYKKPVVTVISTGSEVGVIF 206 Query: 193 -LVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECD 251 ++ P + G + ++N+ L +L + I G + D+++ + + + + D Sbjct: 207 LVLVSPMVENVPLGMVRDSNAPQLVALFKEHGFNVIDGGRVVDDKEGLDKKLTECLEHSD 266 Query: 252 LVLVTGGSAFGDKDY-----AHRFVKLLFHGTTIKPGRPIGYGER----------VFIMS 296 +++ TGG + G++DY H K+ F ++KPG P R V + Sbjct: 267 VIVTTGGVSMGEQDYMKNALLHLGFKIEFGRVSMKPGLPCTVATRESASERKLKVVLALP 326 Query: 297 GYPVAVFAQFHLFVKHALAKMVGARDY-EVKLRAILEDDVPSQLG-RHEFVKVLYR---- 350 G P + + HLF + M G R K+ + D+ +LG R EFV+ Sbjct: 327 GNPASAWVCSHLFAVPLIRDMSGYRRINHTKINVRIAQDI--KLGDRPEFVRAFIEQVGD 384 Query: 351 --DGK--AKVIKKKGSGIISSLVESNAYLEV 377 DG A V K + S I +LV + LE+ Sbjct: 385 EDDGHPIAHVTKNQISSNIGNLVGAQVLLEL 415 >pir||T36508 probable molybdenum cofactor biosynthesis protein - Streptomyces coelicolor >gi|5457262|emb|CAB46950.1| (AL096822) putative molybdenum cofactor biosynthesis protein [Streptomyces coelicolor A3(2)] Length = 465 Score = 119 bits (296), Expect = 5e-26 Identities = 99/372 (26%), Positives = 168/372 (44%), Gaps = 28/372 (7%) Query: 29 VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGE 88 VPLD AL LA + + D+P FD SA+DG+AV + R+ E V AG Sbjct: 93 VPLDAALGLTLAAPLAALTDLPSFDTSAMDGWAVAGPGPWAVRD---------EGVLAGH 143 Query: 89 SPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKR-EGEKIYVLRPVAPGQNVAFKGEDV 147 + + G A+++ TGA+IP AV+ E + E +++ R V GQ++ +G++ Sbjct: 144 AAPAPLIDGEAVRIATGARIPPDTTAVLRTEHGRSDERGRLHPTREVVHGQDIRPRGQEC 203 Query: 148 KKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKI 207 + G+ +L GT+ P L + A G ++ +PRV +++ G EL+ ++ +G I Sbjct: 204 RSGDQLLPVGTLATPAVLGLAAAAGYDTLTAVPRPRVDVLVLGDELL---TQGLPHDGLI 260 Query: 208 VETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYA 267 + ML + E I D+ + A+ + E DL++ TGG+A G D+ Sbjct: 261 RDALGPMLPPWLRALGAEVRTVRRIGDDAKALHRAVTTS--EADLIVTTGGTAAGPVDHV 318 Query: 268 HRFVK-----LLFHGTTIKPGRP-----IGYGERVFIMSGYPVAVFAQFHLFVKHALAKM 317 H ++ LL G +PG P + + + + G P+A + L + L + Sbjct: 319 HPTLRRIGAELLVDGVKARPGHPMLLARLKDDQHLVGLPGNPLAAVSGL-LTLAEPLLRT 377 Query: 318 VGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVESNAYLEV 377 + AR L D V V V+ R A ++ G ++ + ++A V Sbjct: 378 LAARPAPEPYTLPLRDAVHGHPHDTRLVPVVLRGEGAVPLRYNGPAMLRGIAAADALAVV 437 Query: 378 PEDSEGYRRGEE 389 P G R G+E Sbjct: 438 PPG--GARSGQE 447 >sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7445251|pir||E70601 probable MoeAprotein - Mycobacterium tuberculosis (strain H37RV) >gi|2052128|emb|CAB08154.1| (Z94752) moeA [Mycobacterium tuberculosis] Length = 426 Score = 114 bits (282), Expect = 2e-24 Identities = 94/400 (23%), Positives = 181/400 (44%), Gaps = 43/400 (10%) Query: 29 VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIE----------- 77 V + EA + A+++++E +P FD++A+DGYAVR+ D + ++ Sbjct: 23 VAIAEAQGLMCAEEVVTERPMPGFDQAAIDGYAVRSVDVAGVGDTGGVQVFADHGDLDGR 82 Query: 78 ----LKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRP 133 L V+ + AG ++ A++V TGA +P A+AV+ ++ VLR Sbjct: 83 DVLTLPVMGTIEAGARTLSRLQPRQAVRVQTGAPLPTLADAVLPLRWTDGGMSRVRVLRG 142 Query: 134 VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSEL 193 G V G+DV+ G+V +R GTI+ + +L A+G + V V +PR+ ++ G EL Sbjct: 143 APSGAYVRRAGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSVMAVGGEL 202 Query: 194 VEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLV 253 V+ G++ + NS L + E G++ ++ ++ E ++ ++V Sbjct: 203 VDISRTPG--NGQVYDVNSYALAAAGRDACAEVNRVGIVSNDPTELGEIVEGQLNRAEVV 260 Query: 254 LVTGGSAFGDKDYAHRFVKLLFHGTTIK----PGRPIGYGE------RVFIMSGYPVAVF 303 ++ GG + + L ++ PG G+G+ F++ PV+ Sbjct: 261 VIAGGVGGAAAEAVRSVLSELGEMEVVRVAMHPGSVQGFGQLGRDGVPTFLLPANPVSAL 320 Query: 304 AQFHLFVKHALAKMVGARDYEVKLRAILE----DDVPSQLGRHEFVK---VLYRDGKAKV 356 F + V+ + +G R +R I+ + S GR +++ + +D + Sbjct: 321 VVFEVMVRPLIRLSLGKRH---PMRRIVSARTLSPITSVAGRKGYLRGQLMRDQDSGEYL 377 Query: 357 IKKKG------SGIISSLVESNAYLEVPEDSEGYRRGEEV 390 ++ G S ++++L E+N + VP +E R GE V Sbjct: 378 VQALGGAPGASSHLLATLAEANCLVVVPTGAEQIRTGEIV 417 >sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7470744|pir||S75715 molybdopterin biosynthesis protein moeA - Synechocystis sp. (strain PCC 6803) >gi|1001210|dbj|BAA10450.1| (D64003) molybdopterin biosynthesis MoeA [Synechocystis sp.] Length = 390 Score = 111 bits (276), Expect = 1e-23 Identities = 101/371 (27%), Positives = 170/371 (45%), Gaps = 25/371 (6%) Query: 31 LDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESP 90 +D + RVLA+ I ++ D PP DR +DG A+ + Q R + K++ V AG Sbjct: 25 VDGSYGRVLAESIEADRDYPPGDRVMMDGVALAWSEYHQGRRH----FKLLGTVAAGTPQ 80 Query: 91 KMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVA--PGQNVAFKGEDVK 148 ++V+TGA +P+ + VI E V ++ ++ P PG+ V K D + Sbjct: 81 SSLPDQTGCLEVMTGALLPQNCDLVIPYEEVAIADNQVKIINPRQREPGEFVHPKASDCR 140 Query: 149 KGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIV 208 G+VIL + L ++ + G V VK+KPR+ II TG ELVE + + + Sbjct: 141 AGKVILESSSKLNGPAWNIITSFGKTKVRVKQKPRIQIISTGDELVEITQKPKIHQLRRS 200 Query: 209 ETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDY-- 266 + + SL + F L + D+E IR +KAK E +++ +GG + G DY Sbjct: 201 NIYGLQV-SLQSRGFQNVNLTHLADDKEVIIRH-YQKAKLEYRVLIYSGGISKGKFDYLP 258 Query: 267 ---AHRFVKLLFHGTTIKPGRPIGYG-----ERVFI-MSGYPVAVFAQFHLFVKHALAKM 317 + V HG KPG+P+ +G + V I + G P++ H + + A + Sbjct: 259 EVWSQLGVTKYIHGVAQKPGKPMYFGIDHRSKTVIIGLPGNPISSLVCLHRYFLDS-API 317 Query: 318 VGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDGKAKVIKKKGSGIISSLVESNAYLEV 377 + + L +P +L + KA+ + K SG +L S+ +LE+ Sbjct: 318 YAQLTTDFTFKKDLTYFLPVKLSHTPQAVI-----KAEPLPVKNSGEFIALAGSDGFLEL 372 Query: 378 PEDSEGYRRGE 388 P+ ++ GE Sbjct: 373 PQHQASFQAGE 383 >pir||T45454 probable molybdenum cofactor biosynthesis protein [imported] - Mycobacterium leprae >gi|4455711|emb|CAB36697.1| (AL035500) putative molybdenum cofactor biosynthesis protein [Mycobacterium leprae] Length = 424 Score = 110 bits (273), Expect = 2e-23 Identities = 98/398 (24%), Positives = 179/398 (44%), Gaps = 41/398 (10%) Query: 29 VPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIE----------- 77 V + EA + A+++++E +P FD++A+DGYAVR+ D E E Sbjct: 23 VAIAEAQGLMCAEEVMTERPLPGFDQAAIDGYAVRSVDVSGIGESDGGESGSSDEDGRYV 82 Query: 78 --LKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVA 135 L V+ + AG ++ A++V TGA +P A+AV+ ++ +LR Sbjct: 83 LTLPVMGTIEAGARTPSRLLPHQAVRVQTGAPLPVLADAVLPVRWTDGGMSRVRILRGAP 142 Query: 136 PGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVE 195 G V G+DV+ G+V +R GTI+ + +L A+G + V V +PR+ I+ G ELV+ Sbjct: 143 SGAYVRRVGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSIMAVGGELVD 202 Query: 196 EPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLV 255 G++ + NS L + E G++ + + E ++ ++V++ Sbjct: 203 ISRTPG--NGQVYDVNSYALTAAGRDAGAEVNRIGIVSNNLKEFGEVVEGQISRAEVVVI 260 Query: 256 TGGSAFGDKDYAHRFVKLLFHGTTIK----PGRPIGYGE------RVFIMSGYPVAVFAQ 305 GG + + + ++ PG G+G+ F++ PV+ Sbjct: 261 AGGVGGAAAEAVRAVLSEIGEMEVVRVAMHPGSVQGFGQLGREGVPTFLLPANPVSALVV 320 Query: 306 FHLFVKHALAKMVGARDYEVKLRAILE----DDVPSQLGRHEFVK-VLYRD---GKAKVI 357 F + V+ + +G R +R I++ + S GR +++ L RD G+ V Sbjct: 321 FEVMVRPLIRLSLGKRQ---PMRRIVQARTLSPITSVAGRKGYLRGQLMRDQDTGEYLVQ 377 Query: 358 KKKG-----SGIISSLVESNAYLEVPEDSEGYRRGEEV 390 G S ++++L E+N + +P +E R GE V Sbjct: 378 ALGGALGASSHLLATLAEANCLVVIPSGAEQIRTGEVV 415 >pir||G71966 molybdopterin biosynthesis protein - Helicobacter pylori (strain J99) >gi|4154674|gb|AAD05741.1| (AE001454) MOLYBDOPTERIN BIOSYNTHESIS PROTEIN [Helicobacter pylori J99] Length = 390 Score = 108 bits (266), Expect = 2e-22 Identities = 81/333 (24%), Positives = 165/333 (49%), Gaps = 26/333 (7%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 ++ ++EAL + N + +VE V L E+ R+LA+DII +P F++SA+DGY + + Sbjct: 1 MISFKEALKIHSNIPLKPLEVEVVSLFESAGRILAEDIICVHALPKFNQSAMDGYGFKMQ 60 Query: 66 DTFQAREYSPIELKVIEEVPAGES-PKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124 D Q + +VI+ + AG+ ++V +K++TGA +P+G ++ E + E Sbjct: 61 DLGQ-------KTQVIQHIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECM-LE 112 Query: 125 GEKIYVLRP--VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182 K + L P N+ KGE+ V++ K T L +A++ + G K + RK Sbjct: 113 SHKDFALAPKDFKIHANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGFKEIKAFRKL 172 Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242 ++ + +G ELV P E ++ + NS+ + +++ + GV+ D+++ + Sbjct: 173 KIALFSSGDELV--PLGQNALECQVYDVNSVGVFNMLKNY--NTHFLGVLKDDKNLQLKI 228 Query: 243 IKKAKRECDLVLVTGGSAFGDKDY-----AHRFVKLLFHGTTIKPGRPIGYGER----VF 293 ++ + D++L + G + GDKD+ R + +KPG+P+ + + Sbjct: 229 LE--LQGYDVILSSAGVSVGDKDFFKDALKERNALFYYEKVNLKPGKPVTLAQLNQSIII 286 Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARDYEVK 326 + G P++ + + L ++ +D+++K Sbjct: 287 GLPGNPLSCLLVLRVLILPLLERLSLNKDFKLK 319 >pir||F72773 probable molybdopterin biosynthesis protein APE0177 - Aeropyrum pernix (strain K1) >gi|5103567|dbj|BAA79088.1| (AP000058) 386aa long hypothetical molybdopterin biosynthesis protein [Aeropyrum pernix] Length = 386 Score = 107 bits (264), Expect = 3e-22 Identities = 79/257 (30%), Positives = 131/257 (50%), Gaps = 20/257 (7%) Query: 27 EHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPA 86 E +P +++ R+LA+D+ S D P +A+DGYAV D+ A+ + + LK Sbjct: 28 EIIPSSQSVGRILAEDLESPNDTPEEPLAAMDGYAV---DSTSAKPGARLRLK------- 77 Query: 87 GESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPGQNVAFKGED 146 + V SG A+ V TG +P GA+AV+ +E + E IYV V+ +NV GE Sbjct: 78 ---DRGPVASGEAVPVDTGDPLPPGADAVVRREAARVEDGYIYVSAGVSKWENVFRPGEF 134 Query: 147 VKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGK 206 V +G + +G ++ P A++ G+KSV V R + ++ GSEL+ E +G Sbjct: 135 VARGSRLASRGDVISPYLAALIMQAGVKSVKVYRIKSI-VMPVGSELLH--PETMTGDGS 191 Query: 207 IVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDY 266 + ++ L + + EP L +PD +++ EAI +A E D+++ GGS+ G +D Sbjct: 192 LDYIGPMVTGLL--RGWSEPRLVPPVPDGREELEEAINRALDEADILVTIGGSSVGRRDS 249 Query: 267 AHRFVKLLFHGTTIKPG 283 V + G + PG Sbjct: 250 LKALVASM--GQLVVPG 264 >pir||D64541 molybdopterin biosynthesis protein - Helicobacter pylori (strain 26695) >gi|2313255|gb|AAD07237.1| (AE000537) molybdopterin biosynthesis protein (moeA) [Helicobacter pylori 26695] Length = 391 Score = 105 bits (260), Expect = 8e-22 Identities = 75/333 (22%), Positives = 167/333 (49%), Gaps = 26/333 (7%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 ++ ++EAL + + + ++E + L E++ R+LA+DII +P F++SA+DGY + + Sbjct: 1 MISFKEALKIHSSIPIKPLEIEVISLFESIGRILAEDIICIHALPKFNQSAMDGYGFKMQ 60 Query: 66 DTFQAREYSPIELKVIEEVPAGES-PKMKVTSGTAIKVLTGAKIPEGANAVIMQEMVKRE 124 D + + +V++ + AG+ ++V +K++TGA +P+G ++ E + E Sbjct: 61 DLGK-------KTQVVQRIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECM-LE 112 Query: 125 GEKIYVLRP--VAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKP 182 + L P N+ KGE+ V++ K T L +A++ + G+K + RK Sbjct: 113 SHTNFALAPKDFKINANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGLKEIKAFRKL 172 Query: 183 RVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREA 242 ++ + +G ELV P E ++ + NS+ + +++ + GV+ D+++ + Sbjct: 173 KIALFSSGDELV--PLGQNALECQVYDVNSVGIFNMLKNY--NTHFLGVLKDDKNLQLKI 228 Query: 243 IKKAKRECDLVLVTGGSAFGDKDYAHRFVK-----LLFHGTTIKPGRPIGYG----ERVF 293 ++ ++ D++L + G + GDKD+ +K + +KPG+P+ + Sbjct: 229 LE--SQDYDVILSSAGVSVGDKDFFKDALKEKNALFYYEKVNLKPGKPVTLARLNQSMII 286 Query: 294 IMSGYPVAVFAQFHLFVKHALAKMVGARDYEVK 326 + G P++ + + L ++ +D+++K Sbjct: 287 GLPGNPLSCLLVLRVLILPLLERLSLNKDFKLK 319 >emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophila melanogaster] Length = 674 Score = 98.3 bits (241), Expect = 1e-19 Identities = 105/398 (26%), Positives = 186/398 (46%), Gaps = 48/398 (12%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 ++P +E L+++ N V + + LN++L + + + ++PPF S DGYA+++ Sbjct: 271 MLPVQEVLSIIFNTVQKTAN---------LNKILLE-MNAPVNIPPFRASIKDGYAMKST 320 Query: 66 DTFQAREYSPIELKVIEEVPAGESPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-- 122 + +V+ + AG+SP + + K+ TGA +P A+ V+ E K Sbjct: 321 GFSGTK-------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLL 373 Query: 123 ---REGEKIYVLRPVAP--GQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALG-IKSV 176 + G++ V V P G +V G D+ + I L P + + L + + Sbjct: 374 QLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIF---PALDPSPVVVKSLLASVGNR 430 Query: 177 PVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEE 236 + KP+V I+ TGSEL ++ GKI ++N+ ML L+ F + V+ D Sbjct: 431 LILSKPKVAIVSTGSELCSPRNQ--LTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSF 488 Query: 237 DKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-LLFH----GTTIKPGRPIGYGER 291 + +E++ + D V+ +GG + GDKD+ ++ L F IKPG+P+ + R Sbjct: 489 QRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASR 548 Query: 292 ----VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI---LEDDVPSQLGRHEF 344 F + G PV+ F FHLF A+ G + L + L +D S R EF Sbjct: 549 KDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDF-SLDSRPEF 607 Query: 345 VK--VLYRDGK--AKVIKKKGSGIISSLVESNAYLEVP 378 V+ V+ + G+ A V + S + S+V ++ + +P Sbjct: 608 VRASVISKSGELYASVNGNQISSRLQSIVGADVLINLP 645 >emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaster] >gi|7290021|gb|AAF45488.1| (AE003417) cin gene product [Drosophila melanogaster] Length = 601 Score = 98.3 bits (241), Expect = 1e-19 Identities = 105/398 (26%), Positives = 186/398 (46%), Gaps = 48/398 (12%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 ++P +E L+++ N V + + LN++L + + + ++PPF S DGYA+++ Sbjct: 198 MLPVQEVLSIIFNTVQKTAN---------LNKILLE-MNAPVNIPPFRASIKDGYAMKST 247 Query: 66 DTFQAREYSPIELKVIEEVPAGESPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-- 122 + +V+ + AG+SP + + K+ TGA +P A+ V+ E K Sbjct: 248 GFSGTK-------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLL 300 Query: 123 ---REGEKIYVLRPVAP--GQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALG-IKSV 176 + G++ V V P G +V G D+ + I L P + + L + + Sbjct: 301 QLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIF---PALDPSPVVVKSLLASVGNR 357 Query: 177 PVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEE 236 + KP+V I+ TGSEL ++ GKI ++N+ ML L+ F + V+ D Sbjct: 358 LILSKPKVAIVSTGSELCSPRNQ--LTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSF 415 Query: 237 DKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-LLFH----GTTIKPGRPIGYGER 291 + +E++ + D V+ +GG + GDKD+ ++ L F IKPG+P+ + R Sbjct: 416 QRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASR 475 Query: 292 ----VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI---LEDDVPSQLGRHEF 344 F + G PV+ F FHLF A+ G + L + L +D S R EF Sbjct: 476 KDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDF-SLDSRPEF 534 Query: 345 VK--VLYRDGK--AKVIKKKGSGIISSLVESNAYLEVP 378 V+ V+ + G+ A V + S + S+V ++ + +P Sbjct: 535 VRASVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572 >sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAMON >gi|1079093|pir||S47896 probable molybdopterin biosynthesis protein cinnamon - fruit fly (Drosophila melanogaster) >gi|505312|gb|AAA65877.1| (L19876) molybdenum cofactor [Drosophila melanogaster] Length = 601 Score = 97.9 bits (240), Expect = 2e-19 Identities = 105/398 (26%), Positives = 186/398 (46%), Gaps = 48/398 (12%) Query: 6 LMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAE 65 ++P +E L+++ N V + + LN++L + + + ++PPF S DGYA+++ Sbjct: 198 MLPVQEVLSIIFNTVQKTAN---------LNKILLE-MNAPVNIPPFRASIKDGYAMKST 247 Query: 66 DTFQAREYSPIELKVIEEVPAGESPK-MKVTSGTAIKVLTGAKIPEGANAVIMQEMVK-- 122 + +V+ + AG+SP + + K+ TGA +P A+ V+ E K Sbjct: 248 GFSGTK-------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLL 300 Query: 123 ---REGEKIYVLRPVAP--GQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALG-IKSV 176 + G++ V V P G +V G D+ + I L P + + L + + Sbjct: 301 QLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIF---PALDPSPVVVKSLLASVGNR 357 Query: 177 PVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEE 236 + KP+V I+ TGSEL ++ GKI ++N+ ML L+ F + V+ D Sbjct: 358 LILSKPKVAIVSTGSELCSPRNQ--LTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDTF 415 Query: 237 DKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVK-LLFH----GTTIKPGRPIGYGER 291 + +E++ + D V+ +GG + GDKD+ ++ L F IKPG+P+ + R Sbjct: 416 QRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASR 475 Query: 292 ----VFIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAI---LEDDVPSQLGRHEF 344 F + G PV+ F FHLF A+ G + L + L +D S R EF Sbjct: 476 KDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDF-SLDSRPEF 534 Query: 345 VK--VLYRDGK--AKVIKKKGSGIISSLVESNAYLEVP 378 V+ V+ + G+ A V + S + S+V ++ + +P Sbjct: 535 VRASVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572 >pir||H72739 probable molybdopterin biosynthesis moeA protein APE0450 - Aeropyrum pernix (strain K1) >gi|5104096|dbj|BAA79412.1| (AP000059) 577aa long hypothetical molybdopterin biosynthesis moeA protein [Aeropyrum pernix] Length = 577 Score = 96.0 bits (235), Expect = 7e-19 Identities = 100/379 (26%), Positives = 169/379 (44%), Gaps = 19/379 (5%) Query: 27 EHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPA 86 E + L A+ R LA+ ++ PP+ R +DG AV + +R L+V + Sbjct: 40 ESLGLPAAIGRPLARKAVARGCYPPYPRVNLDGCAVDS-----SRVSRGSVLRVTARLRP 94 Query: 87 GESPKMKVT-SGTAIKVLTGAKIPEGANAVIMQEMVKREGEKIYVLRPVAPG-QNVAFKG 144 G P V G + V TGA +P GA+AV+ E + GE + L VA Sbjct: 95 GMEPVELVDREGGCVWVDTGAPLPVGADAVVPLEELDMLGEGVVRLEAEPRRWMGVADPC 154 Query: 145 EDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEE 204 D G V+L +G ++ P+ +A L + G+ V + R + G EL E+ E Sbjct: 155 SDAMDGSVVLGEGEVVTPEAVASLASAGVHDVEAGSRLRACVASVGDEL--RSLEECREG 212 Query: 205 GKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRE-CDLVLVTGGSAFGD 263 G + ETN ++ +S + E + G+ PD + + A+ C +++ +GGS+ G Sbjct: 213 GGVCETNRLLARSRLEAAEVEVVDLGIHPDRPETLSSLAAAARGSGCHILVTSGGSSVGL 272 Query: 264 KDYAHRFVK-LLFHGTTIKPGRP----IGYGERVFIMSGYPVAVFAQFHLFVKHALAKM- 317 DYA + ++ G I+PGRP I G V+ + G P + + LF+ +LA Sbjct: 273 SDYALAGPEDIVVRGLAIRPGRPTTLSIVDGIPVYSLPGNPRSAGSAIDLFLLPSLAAAG 332 Query: 318 VGARDYEVKLRAILEDDV-PSQLGRHEFVKVLYRDGKAKVIKKKGSGIIS-SLVESNAYL 375 + +RA+L V P + + V +Y G+ + ++ S ++ Y+ Sbjct: 333 LPVATVVPGMRAVLLAGVKPGRRLSYIPVAAVYCGGRLYAVPVSTESYMTVSWAAADGYI 392 Query: 376 EVPEDSEGYRRGEEVWITL 394 V E + GEE +T+ Sbjct: 393 AV-EPGKALEPGEEASVTI 410 >pir||T42407 gephyrin homolog - Caenorhabditis elegans >gi|2811220|gb|AAB97841.1| (AF042069) LIN-46 [Caenorhabditis elegans] >gi|2811222|gb|AAB97842.1| (AF042070) LIN-46 [Caenorhabditis elegans] Length = 391 Score = 91.3 bits (223), Expect = 2e-17 Identities = 82/292 (28%), Positives = 130/292 (44%), Gaps = 24/292 (8%) Query: 37 RVLAQDIISEFDVPPFDRSAVDGYAVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTS 96 R+LA+DII+E+D+P S VDG+A+ RE + V ++ S Sbjct: 42 RILAEDIITEYDIPAQRTSIVDGFAIIVNQLGTKREIVGLSTAVTPY-------NAELIS 94 Query: 97 GTAIKVLTGAKIPEGANAVIMQEMVK--REGEKIYVLRPVAPGQNVAFKGEDVKKGEVIL 154 +++ G +P+GA+ V+ E V +E + I VLR G N+ G + K GE++L Sbjct: 95 NECVRITIGGVVPDGADTVVPIENVALLKEEKCIEVLRKPKEGDNIREVGSEAKTGEILL 154 Query: 155 RKGTILRPQDLAMLKALGIKSVPVKRKPRVGIIITGSELVEEPSEDAFEEGKIVETNSIM 214 + G L + +L ALGI V + +KPRV ++ GS+L +F +++E + Sbjct: 155 KDGHHLDTMSITLLHALGISQVEIYKKPRVCVLSIGSDLNSNKMYGSFNRSQLLE----L 210 Query: 215 LKSLVHKFFGEPILYGVIPDEEDKIREAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL 274 +S I + E+KIR A A C LV V G + +F K Sbjct: 211 FQSQGFTAIDAGSSTEHITEVEEKIRTA---ASFACVLVTVGGAQVIREVAKTLKF-KFE 266 Query: 275 FHGTTIKPGR-PIGYG---ERVFIMSGYP---VAVFAQFHLFVKHALAKMVG 319 PG + G E ++S +P V+ + +LFV L M G Sbjct: 267 IQDVDSTPGNFTVSTGKIDETPVVLSIFPEYHVSSWIGANLFVSPILRAMEG 318 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.318 0.139 0.389 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 145821137 Number of Sequences: 2977 Number of extensions: 6366497 Number of successful extensions: 14529 Number of sequences better than 1.0e-10: 63 Number of HSP's better than 0.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 14271 Number of HSP's gapped (non-prelim): 74 length of query: 395 length of database: 189,106,746 effective HSP length: 58 effective length of query: 337 effective length of database: 154,394,500 effective search space: 52030946500 effective search space used: 52030946500 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 166 (69.1 bits)