BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2026 (PAB2026) DE:GTP-BINDING PROTEIN (387 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75167 GTP-binding protein PAB2026 - Pyrococcus abyssi (str... 761 0.0 pir||H71047 probable developmentally regulated GTP-binding prote... 729 0.0 pir||F72509 probable developmentally regulated GTP-binding prote... 309 3e-83 gi|11499729 GTP-binding protein [Archaeoglobus fulgidus] >gi|742... 286 4e-76 pir||E64465 GTP-binding protein DRG homolog - Methanococcus jann... 264 1e-69 pir||F69083 GTP-binding protein DRG homolog - Methanobacterium t... 249 5e-65 gb|AAK42533.1| GTP binding conserved hypothetical protein [Sulfo... 244 1e-63 gb|AAF21162.1|AC010926_14 (AC010926) putative GTP-binding protei... 233 3e-60 gb|AAF55688.1| (AE003727) CG6195 gene product [Drosophila melano... 232 6e-60 gb|AAF97313.1|AC007843_16 (AC007843) GTP binding protein [Arabid... 230 2e-59 sp|P43690|DRG1_XENLA DEVELOPMENTALLY REGULATED GTP-BINDING PROTE... 229 5e-59 pir||T39192 probable GTP-binding protein - fission yeast (Schiz... 228 7e-59 pir||T42381 probable GTP-binding protein - fission yeast (Schiz... 228 1e-58 gi|4758796 developmentally regulated GTP-binding protein 1; neur... 228 1e-58 gi|11417999 developmentally regulated GTP-binding protein 1 [Hom... 228 1e-58 gi|6681225 developmentally regulated GTP-binding protein 1 [Mus ... 228 1e-58 gb|AAB53256.1| (U66408) GTP-binding protein [Arabidopsis thalian... 227 2e-58 pir||JC1349 GTP-binding protein DRG [validated] - mouse 226 3e-58 emb|CAC12607.1| (AL445067) GTP-binding protein [Thermoplasma aci... 225 6e-58 gb|AAF79465.1|AC022492_9 (AC022492) F1L3.17 [Arabidopsis thaliana] 224 1e-57 pir||T09368 GTP-binding protein F23K16.150 - Arabidopsis thalian... 224 2e-57 gb|AAF58591.1| (AE003823) 128up gene product [Drosophila melanog... 224 2e-57 pir||T43254 GTP-binding protein - Thermoplasma acidophilum >gi|1... 223 2e-57 gi|10946678 developmentally regulated GTP-binding protein 2 [Mus... 221 9e-57 gi|4557537 developmentally regulated GTP-binding protein 2 [Homo... 221 1e-56 sp|P32234|128U_DROME GTP-BINDING PROTEIN 128UP >gi|422452|pir||S... 220 2e-56 gi|6319281 similar to Xenopus GTP-binding protein DRG; Fun11p [S... 220 2e-56 gb|AAC33135.1| (AF035177) GTP-binding protein [Oncorhynchus tsha... 220 2e-56 pir||T31553 hypothetical protein T28D6.6 - Caenorhabditis elegan... 220 2e-56 sp|P17103|YRB1_HALCU HYPOTHETICAL 40 KD GTP-BINDING PROTEIN IN R... 216 4e-55 gi|6321612 Ygr173wp [Saccharomyces cerevisiae] >gi|1723727|sp|P5... 214 1e-54 sp|P34280|YKK3_CAEEL HYPOTHETICAL 64.3 KD GTP-BINDING PROTEIN C0... 213 2e-54 gb|AAF77220.1|AC009601_14 (AC009601) L165.8 [Leishmania major] 204 2e-51 sp|P32235|GTP1_SCHPO GTP-BINDING PROTEIN 1 >gi|419815|pir||JT074... 202 5e-51 gi|11427872 developmentally regulated GTP-binding protein 2 [Hom... 198 1e-49 pir||T06251 GTP binding protein - garden pea >gi|2345148|gb|AAB6... 194 1e-48 emb|CAA19048.2| (AL023587) gtp-binding protein 1. [Schizosacchar... 190 2e-47 pir||T40599 hypothetical protein SPBC649.06 - fission yeast (Sc... 190 2e-47 gb|AAG01361.1|AC068666_8 (AC068666) L165.8 [Leishmania major] 110 2e-23 emb|CAA74319.1| (Y13986) GTP-binding protein [Ostertagia circumc... 104 2e-21 pir||G72586 hypothetical protein APE1164 - Aeropyrum pernix (str... 99 8e-20 pir||T42690 hypothetical protein DKFZp434N1827.1 - human (fragme... 99 1e-19 pir||C64466 GTP-binding protein - Methanococcus jannaschii >gi|1... 96 5e-19 pir||C75402 conserved hypothetical protein - Deinococcus radiodu... 89 1e-16 pir||H71165 probable GTP-binding protein - Pyrococcus horikoshii... 88 2e-16 pir||H75066 GTP-binding protein PAB1357 - Pyrococcus abyssi (str... 87 3e-16 pir||E70354 probable GTP-binding protein - Aquifex aeolicus >gi|... 87 3e-16 gb|AAF97355.1| (AY005820) Obg-like protein [Thermococcus zilligii] 85 2e-15 dbj|BAB07770.1| (AP001520) GTP-binding protein [Bacillus halodur... 84 2e-15 sp|P47270|Y024_MYCGE PROBABLE GTP-BINDING PROTEIN MG024 >gi|1361... 83 5e-15 pir||B72418 conserved hypothetical protein - Thermotoga maritima... 83 6e-15 pir||G82870 GTP-binding protein UU595 [imported] - Ureaplasma ur... 82 8e-15 pir||D70197 GTP-binding protein obg - Lyme disease spirochete >g... 80 6e-14 pir||T40281 gtp-binding protein 1 - fission yeast (Schizosacchar... 80 6e-14 pir||A64591 probable GTP-binding protein gtp1 - Helicobacter pyl... 79 7e-14 pir||A72280 conserved hypothetical protein - Thermotoga maritima... 79 7e-14 pir||B75563 GTP-binding protein Obg - Deinococcus radiodurans (s... 79 1e-13 sp|P75088|Y024_MYCPN PROBABLE GTP-BINDING PROTEIN MG024 HOMOLOG ... 78 1e-13 pir||PC7024 hypothetical 218 protein - Acholeplasma laidlawii (f... 78 1e-13 pir||E71920 hypothetical protein jhp0516 - Helicobacter pylori (... 76 5e-13 emb|CAC12034.1| (AL445065) GTP-binding protein Obg related prote... 76 5e-13 pir||E70477 GTP-binding protein obg - Aquifex aeolicus >gi|29842... 76 8e-13 pir||B82532 GTP-binding protein XF2641 [imported] - Xylella fast... 76 8e-13 pir||H81425 probable GTP-binding protein Cj0096 [imported] - Cam... 75 1e-12 sp|P37518|YYAF_BACSU HYPOTHETICAL 40.1 KD GTP-BINDING PROTEIN IN... 75 1e-12 sp|P44681|YCHF_HAEIN PROBABLE GTP-BINDING PROTEIN HI0393 >gi|107... 75 2e-12 pir||C70129 probable GTP-binding protein BB0235 - Lyme disease s... 74 3e-12 pir||S48582 hypothetical protein - Mycoplasma capricolum (SGC3) ... 73 4e-12 pir||T42036 obg protein - Streptomyces coelicolor >gi|1783290|db... 73 7e-12 pir||S74797 GTP-binding protein obg - Synechocystis sp. (strain ... 72 9e-12 pir||T23645 hypothetical protein M01E5.2 - Caenorhabditis elegan... 72 9e-12 pir||A81367 probable GTP-binding protein Cj0930 [imported] - Cam... 72 9e-12 gb|AAF75096.1|AC007583_32 (AC007583) It is a member of GTP1/OBG ... 72 9e-12 gb|AAF79543.1|AC022464_1 (AC022464) F22G5.1 [Arabidopsis thaliana] 72 9e-12 dbj|BAA13501.1| (D87916) Obg [Streptomyces griseus] 72 1e-11 pir||D81037 GTP-binding protein, probable NMB1838 [imported] - N... 72 1e-11 pir||F71665 hypothetical protein RP604 - Rickettsia prowazekii >... 71 2e-11 dbj|BAA91783.1| (AK001603) unnamed protein product [Homo sapiens] 71 2e-11 dbj|BAB13092.1| (AP001119) hypothetical 43.3 kD GTP-binding prot... 71 2e-11 sp|P42641|YHBZ_ECOLI HYPOTHETICAL 43.3 KD GTP-BINDING PROTEIN IN... 71 3e-11 pir||H83074 GTP-binding protein Obg PA4566 [imported] - Pseudomo... 71 3e-11 pir||T30310 probable GTP binding protein - Lactococcus lactis (f... 70 4e-11 pir||S75088 probable GTP-binding protein sll0245 - Synechocystis... 70 5e-11 sp|P75215|Y384_MYCPN PROBABLE GTP-BINDING PROTEIN MG384 HOMOLOG ... 70 5e-11 pir||F70680 probable obg - Mycobacterium tuberculosis (strain H3... 69 8e-11 >pir||F75167 GTP-binding protein PAB2026 - Pyrococcus abyssi (strain Orsay) >gi|5457931|emb|CAB49421.1| (AJ248284) GTP-BINDING PROTEIN [Pyrococcus abyssi] Length = 387 Score = 761 bits (1944), Expect = 0.0 Identities = 387/387 (100%), Positives = 387/387 (100%) Query: 1 MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60 MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL Sbjct: 1 MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60 Query: 61 EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120 EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP Sbjct: 61 EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120 Query: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL Sbjct: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180 Query: 181 REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE 240 REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE Sbjct: 181 REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE 240 Query: 241 PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL 300 PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL Sbjct: 241 PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL 300 Query: 301 DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG 360 DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG Sbjct: 301 DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG 360 Query: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAR 387 KSVKFPGQRVGPDHVLEDGDIVEIHAR Sbjct: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAR 387 >pir||H71047 probable developmentally regulated GTP-binding protein - Pyrococcus horikoshii >gi|3258101|dbj|BAA30784.1| (AP000006) 387aa long hypothetical developmentally regulated GTP-binding protein [Pyrococcus horikoshii] Length = 387 Score = 729 bits (1861), Expect = 0.0 Identities = 360/387 (93%), Positives = 383/387 (98%) Query: 1 MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60 MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKR+LAELR+EL Sbjct: 1 MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRRLAELRREL 60 Query: 61 EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120 EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP+P Sbjct: 61 EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPVP 120 Query: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180 AMMNYKDVQIQLVEVPGL+EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQM+ILL Sbjct: 121 AMMNYKDVQIQLVEVPGLLEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMEILL 180 Query: 181 REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE 240 REFERAGIKVNKRRPR+EIR+TPSGGIVING ENIKGD++EVM+MLREEKIHSAEITV+E Sbjct: 181 REFERAGIKVNKRRPRVEIRKTPSGGIVINGAENIKGDLSEVMRMLREEKIHSAEITVKE 240 Query: 241 PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL 300 PVTLE+FADALD+SLVWKKAIIIANKGD+PGSK+NY KL+ YGE+FKI+PVSAKKRINL Sbjct: 241 PVTLEEFADALDDSLVWKKAIIIANKGDSPGSKENYHKLINKYGEKFKIVPVSAKKRINL 300 Query: 301 DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG 360 +AVKEA+YDVAEIIRVFTKSPGEEPAYPPIALKRG+TV+DVAERIHKDLVKNFRYARVWG Sbjct: 301 EAVKEAIYDVAEIIRVFTKSPGEEPAYPPIALKRGATVMDVAERIHKDLVKNFRYARVWG 360 Query: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAR 387 KSVKFPGQRVGPDHVLEDGDIVEIHA+ Sbjct: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAK 387 >pir||F72509 probable developmentally regulated GTP-binding protein APE2052 - Aeropyrum pernix (strain K1) >gi|5105750|dbj|BAA81062.1| (AP000063) 368aa long hypothetical developmentally regulated GTP-binding protein [Aeropyrum pernix] Length = 368 Score = 309 bits (784), Expect = 3e-83 Identities = 171/369 (46%), Positives = 242/369 (65%), Gaps = 8/369 (2%) Query: 24 EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83 EKI+ALE+ + VPKHKGTE L L +R+LAELR+ELE++R++R GGG S V+K GA Q Sbjct: 3 EKIQALEEFISAVPKHKGTENLLLWARRRLAELREELEEKRKRRVGGGPSFFVEKSGAGQ 62 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 VL+G PN GKS +L ALT E ADYPFTT P M+ Y+D+Q Q+V+ P L+ G+ Sbjct: 63 AVLIGPPNSGKSSILAALTNAKPEVADYPFTTRMPRAGMLPYEDIQFQIVDTPPLLPGS- 121 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDP--IKQMKILLREFERAGIKVNKRRPRIEIRR 201 G + ++L + RNADAI +V L +DP ++ + ++RE E GI + +RR I + Sbjct: 122 -GSSVNNRVLGLARNADAIILVFSL-DDPNLVETIDAVVREVEDRGIVITRRRGLARIMK 179 Query: 202 TPS-GGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259 + G+ I G + ++V ++L + +I++A + + V+L+D A+ +LV K Sbjct: 180 SREVTGVRIEGPGRLTDATEDDVRRLLSQYRIYNAIVYIEGDVSLDDVESAVYINLVRKP 239 Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGE-RFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318 A+ I NK D PG+++ E VK GE I SA + L + L+ + +I+RV+T Sbjct: 240 ALAILNKADLPGAREAAEPAVKRLGEIGIDTIVASALRGDGLGEIAPRLFRMLDIVRVYT 299 Query: 319 KSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378 K P +EP P+ L RGSTV+DVA+ IHKDLV+ F+YARVWGKSVK+PGQRVGP+HV+ED Sbjct: 300 KQPNKEPDKDPLVLHRGSTVMDVAKHIHKDLVRRFKYARVWGKSVKYPGQRVGPEHVVED 359 Query: 379 GDIVEIHAR 387 GDIVEIH R Sbjct: 360 GDIVEIHVR 368 >gi|11499729 GTP-binding protein [Archaeoglobus fulgidus] >gi|7428740|pir||B69518 GTP-binding protein DRG homolog - Archaeoglobus fulgidus >gi|2648391|gb|AAB89108.1| (AE000956) GTP-binding protein [Archaeoglobus fulgidus] Length = 355 Score = 286 bits (723), Expect = 4e-76 Identities = 157/367 (42%), Positives = 231/367 (62%), Gaps = 17/367 (4%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80 +I ++IR LE+ P +K TE ++K KLA LR+E EKQ+ + +SL KKEG Sbjct: 5 SIEQQIRELEEEIKRTPYNKATEHHIGRLKAKLARLREEAEKQKAKAARQAFSL--KKEG 62 Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140 A VL+G P+VGKS LL LTG E ADY FTT +P+P ++NYK IQ+++VPG+IE Sbjct: 63 DATAVLIGYPSVGKSTLLNKLTGAKSEVADYDFTTLKPVPGILNYKGASIQIIDVPGIIE 122 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200 GAA G+G G ++++ +R AD I IV D+ + + I+ RE GI+++++ P + IR Sbjct: 123 GAASGRGRGKEVISAVRVADLIIIVADVFN--LHTIDIVKRELYEGGIRLDQKPPDVVIR 180 Query: 201 RTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 + GG+ I+ + D + +L+E KIHSA++ +RE +T+E DAL + V+ + Sbjct: 181 KKERGGVRISSTVPLSIDEATITSVLKEYKIHSADVVIREDITIERLIDALAGNRVYIPS 240 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + NK D + I VSA+K INLD +KE +Y E IRV+ K Sbjct: 241 LTVVNKIDLMDV------------DVADAIKVSAEKGINLDLLKEQIYRKLEFIRVYLKP 288 Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379 PG + + P+ L+RG+TV D+ ++H+D V+NFRYA+VWGKSVKF GQRVG +HV+EDG Sbjct: 289 PGGKVDFSEPMILRRGATVEDICRKLHRDFVENFRYAKVWGKSVKFDGQRVGLEHVVEDG 348 Query: 380 DIVEIHA 386 DI+ I+A Sbjct: 349 DIITIYA 355 >pir||E64465 GTP-binding protein DRG homolog - Methanococcus jannaschii >gi|1591967|gb|AAB99336.1| (U67573) GTP-binding protein, member of GTP1/OBG-family [Methanococcus jannaschii] Length = 391 Score = 264 bits (668), Expect = 1e-69 Identities = 146/367 (39%), Positives = 225/367 (60%), Gaps = 10/367 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I E+IR +E+ P +K T+K ++K KLA+LR++ Q + GGG AVKK G Sbjct: 27 IEEEIRRIEEELKKTPYNKATQKHIGRLKAKLAKLREQA--QSRGGGGGGKGYAVKKSGD 84 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 A VG P+VGKS LL LT E Y FTT +P ++ YK +IQL++ PG+I G Sbjct: 85 ATAAFVGFPSVGKSTLLNKLTNAKSEVGAYAFTTLTIVPGILEYKGAKIQLLDAPGIIVG 144 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 A+ GKG G ++L+ +R+AD I + +D+ + + +L +E GI++++ P ++I+ Sbjct: 145 ASSGKGRGTEVLSAVRSADLILLTVDIY--TLDHLPVLEKELYNVGIRLDQTPPDVKIKV 202 Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 GGI ++ + D + + +L E +IH+A++ +RE +TLE F D + + V+ + Sbjct: 203 KERGGINVSSTVPLTHIDEDTIEAILNEYRIHNADVVIREDITLEQFIDVVAGNRVYIPS 262 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERF--KIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318 +++ NK D + + Y K +K E F I VS K INLD +KE +Y+ I+++ Sbjct: 263 LVVVNKIDL--ADEEYLKYIKQKLEEFGKDYILVSGNKGINLDLLKEKIYEKLGFIKIYL 320 Query: 319 KSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377 K G++P + P+ ++RG+TV DV E++HKD V+NFRYA+VWGKS K PGQRVG DH LE Sbjct: 321 KPQGKKPDFDEPLIMRRGATVKDVCEKLHKDFVRNFRYAQVWGKSAKHPGQRVGLDHKLE 380 Query: 378 DGDIVEI 384 DGDI+ I Sbjct: 381 DGDILTI 387 >pir||F69083 GTP-binding protein DRG homolog - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622747|gb|AAB86094.1| (AE000921) GTP-binding protein, GTP1/OBG family [Methanobacterium thermoautotrophicum] Length = 380 Score = 249 bits (628), Expect = 5e-65 Identities = 134/366 (36%), Positives = 222/366 (60%), Gaps = 11/366 (3%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I EKIR +E+ P +K T ++K K++ L++E QR+ G G +KK G Sbjct: 19 IEEKIRKIEEEIQKTPYNKATAHHIGKLKAKISRLKEEA-LQRKTSSGKGRGFHIKKSGD 77 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 + +VL+G P+VGKS LL LT + + DY FTT E +P +M Y+ QIQ+ ++PG+I G Sbjct: 78 STVVLIGFPSVGKSTLLNELTSAESKVGDYQFTTLEIVPGVMEYRGAQIQIFDIPGIITG 137 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 A+ G+G G ++L+V R+AD I IV+D+ M I+LRE GI+ N+ P + ++R Sbjct: 138 ASRGRGRGREILSVARSADLIVIVLDVFN--TDHMDIILRELRDVGIRPNETPPDVIVKR 195 Query: 202 TPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 GG+ ++ +E D + +L E IH+A++ +R+ +T++ F D ++ + + A Sbjct: 196 RKLGGVKLSATVELTHLDEKIIRSVLNEYGIHNADVLIRDDITVDQFIDVMEANRAYIPA 255 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERF-KIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319 I + NK D E ++ E+F + + +SA + IN+D ++E +++ +IR++ K Sbjct: 256 ITVINKIDLVD-----ESYLEGLREKFPEALFISADRDINIDELREEIFNRLGLIRIYLK 310 Query: 320 SPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378 G++ Y P+ ++ GSTV DV +++H+D V+ FR+ARVWG SVKF GQ+VG +HVL D Sbjct: 311 PQGKKADYDEPLIIREGSTVGDVCQKLHRDFVRKFRHARVWGSSVKFDGQKVGLEHVLND 370 Query: 379 GDIVEI 384 D++ I Sbjct: 371 EDVLRI 376 >gb|AAK42533.1| GTP binding conserved hypothetical protein [Sulfolobus solfataricus] Length = 351 Score = 244 bits (617), Expect = 1e-63 Identities = 163/390 (41%), Positives = 230/390 (58%), Gaps = 42/390 (10%) Query: 1 MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60 M TN+ AE A + +AKT EK +AL++ VPKHKGTE L KR++AELR+E+ Sbjct: 1 MVTNLPAEAKAKWLKVMDAKTPEEKFQALQEFLKEVPKHKGTENLVYWAKRRMAELREEM 60 Query: 61 EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120 E R+ +K GG+SL V+KEGA Q +L+G + +S ++R LT V E + P +P Sbjct: 61 EV-RKSKKSGGFSLFVEKEGAGQAILIG-DMLLRSFIMRKLTNVKQEFNELP------VP 112 Query: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180 M+ Y+DVQIQLV P + L K +G +IRNAD + I I+ ED + +K LL Sbjct: 113 GMVKYEDVQIQLVNPP---KSLPLSKTIG-----LIRNADEVIIAINNKED-LSLIKSLL 163 Query: 181 REFERAGIKVNKRRPRIEIRRTPSG--GIVINGIENIKG-DINEVMKMLREEKIHSAEIT 237 E I + K + R+ I RT G GI + + + G D V + I SA + Sbjct: 164 ---EDNNILLRKPKGRVVIERTRYGISGIRVVNLGKLIGIDEKVVRDYIESFGIKSAIVK 220 Query: 238 VREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKR 297 + VTL+D ++ E++ +K ++I SKD ++ GE +P+ + Sbjct: 221 IIGEVTLDDIEKSMFEAVSYKPTVVI--------SKDRFDT-----GE----LPMLTIDQ 263 Query: 298 INLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYAR 357 I D + + L+D+ E+IRV+TK PGEEP P+ LK+GSTVLDVA ++H L +NFRYAR Sbjct: 264 I--DKLPKHLFDMLEVIRVYTKEPGEEPTKDPLILKKGSTVLDVARKLHSSLAENFRYAR 321 Query: 358 VWGKSVKFPGQRVGPDHVLEDGDIVEIHAR 387 VWGKSVKF GQ+VGP H+LED DIVEIH + Sbjct: 322 VWGKSVKFQGQKVGPSHILEDRDIVEIHVK 351 >gb|AAF21162.1|AC010926_14 (AC010926) putative GTP-binding protein; 56356-53974 [Arabidopsis thaliana] Length = 399 Score = 233 bits (587), Expect = 3e-60 Identities = 134/368 (36%), Positives = 213/368 (57%), Gaps = 11/368 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I E+I+ +E A K+K TE Q+K K+A+LR +L + + GGG V K G Sbjct: 3 IVERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGSSGGGDGFEVTKYGH 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 ++ L+G P+VGKS LL LTG E+A Y FTT IP +++Y D +IQL+++PG+IEG Sbjct: 63 GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 A+ GKG G Q++AV +++D + +V+D S+ +IL +E E G+++NKR P+I ++ Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKSE-GHRQILTKELEAVGLRLNKRPPQIYFKK 181 Query: 202 TPSGGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 +GGI N + + D ++L E KIH+AE+ RE T++DF D ++ + + K Sbjct: 182 KKTGGISFNTTTPLTRIDEKLCYQILHEYKIHNAEVLFREDATVDDFIDVVEGNRKYIKC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + NK D G D V + I +S ++NLD + ++D ++RV++K Sbjct: 242 VYVYNKIDVVGIDD-----VDRLARQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKP 296 Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376 ++P + P L + G TV D ++H+ LVK+ +YA VWG S + Q G H L Sbjct: 297 QSQQPDFDEPFVLSADRGGCTVEDFCNQVHRTLVKDMKYALVWGTSARHYPQHCGLFHHL 356 Query: 377 EDGDIVEI 384 ED D+V+I Sbjct: 357 EDEDVVQI 364 >gb|AAF55688.1| (AE003727) CG6195 gene product [Drosophila melanogaster] Length = 363 Score = 232 bits (585), Expect = 6e-60 Identities = 135/366 (36%), Positives = 213/366 (57%), Gaps = 11/366 (3%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL-EKQRQQRKGGGYSLAVKKEG 80 I EKI +E+ A K+K TE +K KLA+ R +L E ++ KG G+ V K G Sbjct: 3 ILEKIAEIEREIARTQKNKATEYHLGLLKAKLAKYRSQLLEPSKKGEKGDGFD--VLKSG 60 Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140 A++ L+G P+VGKS +L LT + E+A+Y FTT IP ++ Y+ IQL+++PG+IE Sbjct: 61 DARVALIGFPSVGKSTMLSTLTKTESEAANYEFTTLTCIPGVIEYQGANIQLLDLPGIIE 120 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200 GAA GKG G Q++AV R AD + +++D ++ P ++L RE E GI++NKR+P I + Sbjct: 121 GAAQGKGRGRQVIAVARTADLVLMMLDATK-PNVHRELLERELESVGIRLNKRKPNIYFK 179 Query: 201 RTPSGGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259 + GG+ N ++ + + V +L KI +AE+ RE T ++F D + + V+ Sbjct: 180 QKKGGGLSFNATCSLTRCNEKMVQTILHSFKIFNAEVLFREDCTEDEFIDVVTANRVYLP 239 Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319 + + NK D ++ V + I VS ++NLD + EAL++ ++IRV+TK Sbjct: 240 CLYVYNKIDQISIEE-----VDRLARQPNSIVVSCNMKLNLDYMMEALWEALQLIRVYTK 294 Query: 320 SPGEEPAYPP-IALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378 PG P + + L++G +V V IH+ L F+YA VWG S K+ QRVG HV+ D Sbjct: 295 KPGAPPDFDDGLILRKGVSVEHVCHAIHRTLAAQFKYALVWGTSTKYSPQRVGIAHVMAD 354 Query: 379 GDIVEI 384 D++++ Sbjct: 355 EDVIQV 360 >gb|AAF97313.1|AC007843_16 (AC007843) GTP binding protein [Arabidopsis thaliana] Length = 399 Score = 230 bits (581), Expect = 2e-59 Identities = 133/368 (36%), Positives = 210/368 (56%), Gaps = 11/368 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I E+I+ +E A K+K TE Q+K K+A+LR +L + + GGG V K G Sbjct: 3 IIERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGASGGGEGFEVTKYGH 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 ++ L+G P+VGKS LL LTG E+A Y FTT IP +++Y D +IQL+++PG+IEG Sbjct: 63 GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 A+ GKG G Q++AV +++D + +V+D S+ +IL +E E G+++NK P+I ++ Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKSE-GHRQILTKELEAVGLRLNKTPPQIYFKK 181 Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 +GGI N + D ++L E KIH+AE+ RE T++DF D ++ + + K Sbjct: 182 KKTGGISFNTTAPLTHIDEKLCYQILHEYKIHNAEVLFRENATVDDFIDVIEGNRKYIKC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + NK D G D V + I +S ++NLD + ++D ++RV++K Sbjct: 242 VYVYNKIDVVGIDD-----VDRLSRQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKP 296 Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376 G++P + P L + G TV D +H+ LVK+ +YA VWG S + Q G L Sbjct: 297 QGQQPDFDEPFVLSSDRGGCTVEDFCNHVHRTLVKDMKYALVWGTSTRHNPQNCGLSQHL 356 Query: 377 EDGDIVEI 384 ED D+V+I Sbjct: 357 EDEDVVQI 364 >sp|P43690|DRG1_XENLA DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN 1 (DRG 1) (XDRG) >gi|2120159|pir||I51426 GTP-binding protein DRG - African clawed frog >gi|433422|dbj|BAA02978.1| (D13865) GTP-binding protein DRG [Xenopus laevis] Length = 367 Score = 229 bits (577), Expect = 5e-59 Identities = 142/364 (39%), Positives = 210/364 (57%), Gaps = 10/364 (2%) Query: 25 KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83 +I +E A K+K T +K +LA+LR+EL + GG G V K G A+ Sbjct: 7 RIAEIEAEMARTQKNKATAYHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 I VG P+VGKS LL L GV E A Y FTT +P ++ YK +IQL+++PG+IEGA Sbjct: 67 IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVVRYKGAKIQLLDLPGIIEGAK 126 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203 GKG G Q++AV R + I IV+D+ + P+ KI+ E E GI++NK+ P I ++ Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNKQPPNIGFKKKD 185 Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262 GGI + + D + V +L E KIH+A+IT+R T +D D ++ + V+ I Sbjct: 186 KGGINLTATCAQSELDNDTVKSILAEYKIHNADITLRSDATADDLIDVVEGNRVYIPCIY 245 Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322 + NK D + + E+L Y + +P+SA R N D + E ++D +++R++TK G Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLQLVRIYTKPKG 300 Query: 323 EEPAY-PPIALKRGSTVL-DVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380 + P Y P+ L T D +IHK+L+K F+YA VWG SVK Q+VG DHVLED D Sbjct: 301 QLPDYTSPVVLPCSHTAAEDFCTKIHKNLIKEFKYALVWGSSVKHNPQKVGKDHVLEDED 360 Query: 381 IVEI 384 +++I Sbjct: 361 VIQI 364 >pir||T39192 probable GTP-binding protein - fission yeast (Schizosaccharomyces pombe) >gi|6014426|emb|CAB57425.1| (AL121764) putative GTP-binding protein [Schizosaccharomyces pombe] Length = 366 Score = 228 bits (576), Expect = 7e-59 Identities = 131/369 (35%), Positives = 208/369 (55%), Gaps = 13/369 (3%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80 T +KI+ +E A K+K T K +K KLA+L++EL GGG V + G Sbjct: 3 TTAQKIKEVEDEMAKTQKNKATAKHLGMLKAKLAKLKRELITPTGGGGGGGLGFDVARTG 62 Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140 + +G P+VGKS L+ LTG E+A Y FTT +P ++ Y +IQ++++PG+IE Sbjct: 63 IGTVGFIGFPSVGKSTLMTQLTGTRSEAAAYEFTTLTTVPGVLQYNGAKIQILDLPGIIE 122 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200 GA G+G G Q++ V R + I IV+D+ + P+ +I+ E E GI++NK P I + Sbjct: 123 GAKDGRGRGKQVITVARTCNLIFIVLDVLK-PMSHKRIIEEELEGFGIRLNKEPPNIVFK 181 Query: 201 RTPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259 + GGI + N + D++E+ + E +++SA+I R T++D D L+ + V+ Sbjct: 182 KKERGGINITNTVPLTHIDLDEIRAVCSEYRVNSADIAFRCDATIDDLIDVLEGNRVYIP 241 Query: 260 AIIIANKGDAPGSK--DNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVF 317 A+ + NK D+ + D +++ A +P+ + N+D +KE ++D ++RV+ Sbjct: 242 ALYVLNKIDSISIEELDLIDRIPNA-------VPICGNRGWNIDELKETMWDYLNLVRVY 294 Query: 318 TKSPGEEPAY-PPIALKRG-STVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375 T+ G EP Y P+ L+ G STV D IH + F++A VWGKSV +PG RVG HV Sbjct: 295 TRPRGLEPDYSEPVILRTGHSTVEDFCNNIHSSIKSQFKHAYVWGKSVPYPGMRVGLSHV 354 Query: 376 LEDGDIVEI 384 L D D+V I Sbjct: 355 LLDEDVVTI 363 >pir||T42381 probable GTP-binding protein - fission yeast (Schizosaccharomyces pombe) >gi|1749478|dbj|BAA13797.1| (D89135) similar to Xenopus laevis developing GTP-binding protein DRG, SWISS-PROT Accession Number P43690 [Schizosaccharomyces pombe] Length = 366 Score = 228 bits (574), Expect = 1e-58 Identities = 131/369 (35%), Positives = 208/369 (55%), Gaps = 13/369 (3%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80 T +KI+ +E A K+K T K +K KLA+L++EL GGG V + G Sbjct: 3 TTAQKIKEVEDEMAKTQKNKATAKHLGMLKAKLAKLKRELITPTGGGGGGGLGFDVARTG 62 Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140 + +G P+VGKS L+ LTG E+A Y FTT +P ++ Y +IQ++++PG+IE Sbjct: 63 IGTVGFIGFPSVGKSTLMTQLTGTRSEAAAYEFTTLTTVPGVLQYNGAKIQILDLPGIIE 122 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200 GA G+G G Q++ V R + I IV+D+ + P+ +I+ E E GI++NK P I + Sbjct: 123 GAKDGRGRGKQVITVARTCNLIFIVLDVLK-PMSHKRIIEEELEGFGIRLNKEPPNIVFK 181 Query: 201 RTPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259 + GGI + N + D++E+ + E +++SA+I R T++D D L+ + V+ Sbjct: 182 KKERGGINITNTVPLTHIDLDEIRAVCSEYRVNSADIAFRCDSTIDDLIDVLEGNRVYIP 241 Query: 260 AIIIANKGDAPGSK--DNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVF 317 A+ + NK D+ + D +++ A +P+ + N+D +KE ++D ++RV+ Sbjct: 242 ALYVLNKIDSISIEELDLIDRIPNA-------VPICGNRGWNIDELKETMWDYLNLVRVY 294 Query: 318 TKSPGEEPAY-PPIALKRG-STVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375 T+ G EP Y P+ L+ G STV D IH + F++A VWGKSV +PG RVG HV Sbjct: 295 TRPRGLEPDYSEPVILRTGHSTVEDFCNNIHSSIKSQFKHAYVWGKSVPYPGMRVGLSHV 354 Query: 376 LEDGDIVEI 384 L D D+V I Sbjct: 355 LLDEDVVTI 363 >gi|4758796 developmentally regulated GTP-binding protein 1; neural precursor cell expressed, developmentally down-regulated 3 [Homo sapiens] >gi|6685390|sp|Q9Y295|DRG1_HUMAN DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN 1 (DRG 1) >gi|4127988|emb|CAA06775.1| (AJ005940) GTP-binding protein [Homo sapiens] >gi|4218945|gb|AAD12240.1| (AF078103) developmentally regulated GTP-binding protein [Homo sapiens] Length = 367 Score = 228 bits (574), Expect = 1e-58 Identities = 140/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%) Query: 25 KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83 KI +E A K+K T +K +LA+LR+EL + GG G V K G A+ Sbjct: 7 KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 I VG P+VGKS LL L GV E A Y FTT +P ++ YK +IQL+++PG+IEGA Sbjct: 67 IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 126 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203 GKG G Q++AV R + I IV+D+ + P+ KI+ E E GI++N + P I ++ Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 185 Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262 GGI + + D V +L E KIH+A++T+R T +D D ++ + V+ I Sbjct: 186 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIY 245 Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322 + NK D + + E+L Y + +P+SA R N D + E ++D +++R++TK G Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 300 Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380 + P Y P + +TV D +IHK+L+K F+YA VWG SVK Q+VG DH LED D Sbjct: 301 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 360 Query: 381 IVEI 384 +++I Sbjct: 361 VIQI 364 >gi|11417999 developmentally regulated GTP-binding protein 1 [Homo sapiens] Length = 389 Score = 228 bits (574), Expect = 1e-58 Identities = 140/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%) Query: 25 KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83 KI +E A K+K T +K +LA+LR+EL + GG G V K G A+ Sbjct: 29 KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 88 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 I VG P+VGKS LL L GV E A Y FTT +P ++ YK +IQL+++PG+IEGA Sbjct: 89 IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 148 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203 GKG G Q++AV R + I IV+D+ + P+ KI+ E E GI++N + P I ++ Sbjct: 149 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 207 Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262 GGI + + D V +L E KIH+A++T+R T +D D ++ + V+ I Sbjct: 208 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIY 267 Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322 + NK D + + E+L Y + +P+SA R N D + E ++D +++R++TK G Sbjct: 268 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 322 Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380 + P Y P + +TV D +IHK+L+K F+YA VWG SVK Q+VG DH LED D Sbjct: 323 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 382 Query: 381 IVEI 384 +++I Sbjct: 383 VIQI 386 >gi|6681225 developmentally regulated GTP-binding protein 1 [Mus musculus] >gi|416914|sp|P32233|DRG1_MOUSE DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN 1 (DRG 1) (NEDD3 PROTEIN) >gi|220507|dbj|BAA01555.1| (D10715) GTP-binding protein [Mus musculus] Length = 367 Score = 228 bits (574), Expect = 1e-58 Identities = 140/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%) Query: 25 KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83 KI +E A K+K T +K +LA+LR+EL + GG G V K G A+ Sbjct: 7 KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 I VG P+VGKS LL L GV E A Y FTT +P ++ YK +IQL+++PG+IEGA Sbjct: 67 IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 126 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203 GKG G Q++AV R + I IV+D+ + P+ KI+ E E GI++N + P I ++ Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 185 Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262 GGI + + D V +L E KIH+A++T+R T +D D ++ + V+ I Sbjct: 186 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIY 245 Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322 + NK D + + E+L Y + +P+SA R N D + E ++D +++R++TK G Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 300 Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380 + P Y P + +TV D +IHK+L+K F+YA VWG SVK Q+VG DH LED D Sbjct: 301 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 360 Query: 381 IVEI 384 +++I Sbjct: 361 VIQI 364 >gb|AAB53256.1| (U66408) GTP-binding protein [Arabidopsis thaliana] >gi|2345150|gb|AAB67830.1| (AF014822) developmentally regulated GTP binding protein [Arabidopsis thaliana] Length = 399 Score = 227 bits (572), Expect = 2e-58 Identities = 132/368 (35%), Positives = 209/368 (55%), Gaps = 11/368 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I E+I+ +E A K+K TE Q+K K+A+LR +L + + GGG V K G Sbjct: 3 IIERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGASGGGEGFEVTKYGH 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 ++ L+G P+VGKS LL LTG E+A Y FTT IP +++Y D +IQL+++PG+IEG Sbjct: 63 GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 A+ GKG G Q++AV +++D + +V+D S+ +IL +E E G+++NK P+I ++ Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKSE-GHRQILTKELEAVGLRLNKTPPQIYFKK 181 Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 +GGI N + D ++L E KIH+AE+ RE T++DF D ++ + + K Sbjct: 182 KKTGGISFNTTAPLTHIDEKLCYQILHEYKIHNAEVLFRENATVDDFIDVIEGNRKYIKC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + K D G D V + I +S ++NLD + ++D ++RV++K Sbjct: 242 VYVYIKIDVVGIDD-----VDRLSRQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKP 296 Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376 G++P + P L + G TV D +H+ LVK+ +YA VWG S + Q G L Sbjct: 297 QGQQPDFDEPFVLSSDRGGCTVEDFCNHVHRTLVKDMKYALVWGTSTRHNPQNCGLSQHL 356 Query: 377 EDGDIVEI 384 ED D+V+I Sbjct: 357 EDEDVVQI 364 >pir||JC1349 GTP-binding protein DRG [validated] - mouse Length = 367 Score = 226 bits (570), Expect = 3e-58 Identities = 139/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%) Query: 25 KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83 KI +E A K+K T +K +LA+LR+EL + GG G V K G A+ Sbjct: 7 KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 I VG P+VGKS LL L GV E A Y FTT +P ++ YK +IQL+++PG+IEGA Sbjct: 67 IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 126 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203 GKG G Q++AV R + I IV+D+ + P+ KI+ E E GI++N + P I ++ Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 185 Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262 GGI + + D V +L E KIH+A++T+R T ++ D ++ + V+ I Sbjct: 186 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADELIDVVEGNRVYIPCIY 245 Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322 + NK D + + E+L Y + +P+SA R N D + E ++D +++R++TK G Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 300 Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380 + P Y P + +TV D +IHK+L+K F+YA VWG SVK Q+VG DH LED D Sbjct: 301 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 360 Query: 381 IVEI 384 +++I Sbjct: 361 VIQI 364 >emb|CAC12607.1| (AL445067) GTP-binding protein [Thermoplasma acidophilum] Length = 360 Score = 225 bits (568), Expect = 6e-58 Identities = 136/369 (36%), Positives = 215/369 (57%), Gaps = 14/369 (3%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79 TI E+I+ +E +K TE +K K+A+L+ E GG +S AV K Sbjct: 3 TIEERIKEIEDEIKRTQYNKATEHHIGLLKAKIAKLQMEASASH----GGSHSGFAVPKS 58 Query: 80 GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139 G A + LVG PNVGKS LL LT + E DY FTT +PIP ++ YK +IQ++++PG+I Sbjct: 59 GDATVALVGFPNVGKSSLLNRLTNSESEIGDYAFTTLQPIPGILEYKGAEIQILDLPGII 118 Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199 E A+ G G ++L+ +R AD I IV D+ I + +L E AGI VN++R +EI Sbjct: 119 ENASYGSARGREILSAVRAADLIVIVTDVQAGGIDK---ILTELYNAGIVVNRKRRNVEI 175 Query: 200 RRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259 R+T SGGI ++ +N+ D + + ++++E K+ +A++ +RE V++ED + L V+ Sbjct: 176 RKTTSGGIRLHRPKNVDIDEDYIKEIMKEFKLVNADVYIRENVSVEDIIETLQGRYVYIP 235 Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319 +I+ NK D S D + V YGE F+ VSAK ++ +KE ++ +IR++ + Sbjct: 236 SIVAVNKIDMNPSFDTSQ--VSQYGEVFR---VSAKTGYGIEELKEGIFRSLNLIRIYLR 290 Query: 320 S-PGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378 + G P+ ++ G+TV +V +I++ ++ +FRYA V GK+ QRVG D+ L D Sbjct: 291 NKAGVVDFQKPLIVREGTTVREVCRKINRSMIDSFRYAIVSGKNRPIGEQRVGIDYPLMD 350 Query: 379 GDIVEIHAR 387 DIV I +R Sbjct: 351 EDIVTIISR 359 >gb|AAF79465.1|AC022492_9 (AC022492) F1L3.17 [Arabidopsis thaliana] Length = 412 Score = 224 bits (566), Expect = 1e-57 Identities = 133/380 (35%), Positives = 210/380 (55%), Gaps = 22/380 (5%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I E+I+ +E A K+K TE Q+K K+A+LR +L + + GGG V K G Sbjct: 3 IIERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGASGGGEGFEVTKYGH 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 ++ L+G P+VGKS LL LTG E+A Y FTT IP +++Y D +IQL+++PG+IEG Sbjct: 63 GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPI------------KQMKILLREFERAGIK 189 A+ GKG G Q++AV +++D + +V+D S+ +IL +E E G++ Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKVSYGLYVHVNWYMSEGHRQILTKELEAVGLR 182 Query: 190 VNKRRPRIEIRRTPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFA 248 +NK P+I ++ +GGI N + D ++L E KIH+AE+ RE T++DF Sbjct: 183 LNKTPPQIYFKKKKTGGISFNTTAPLTHIDEKLCYQILHEYKIHNAEVLFRENATVDDFI 242 Query: 249 DALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALY 308 D ++ + + K + + NK D G D V + I +S ++NLD + ++ Sbjct: 243 DVIEGNRKYIKCVYVYNKIDVVGIDD-----VDRLSRQPNSIVISCNLKLNLDRLLARMW 297 Query: 309 DVAEIIRVFTKSPGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVK 364 D ++RV++K G++P + P L + G TV D +H+ LVK+ +YA VWG S + Sbjct: 298 DEMGLVRVYSKPQGQQPDFDEPFVLSSDRGGCTVEDFCNHVHRTLVKDMKYALVWGTSTR 357 Query: 365 FPGQRVGPDHVLEDGDIVEI 384 Q G LED D+V+I Sbjct: 358 HNPQNCGLSQHLEDEDVVQI 377 >pir||T09368 GTP-binding protein F23K16.150 - Arabidopsis thaliana >gi|5042168|emb|CAB44687.1| (AL078620) GTP-binding-like protein [Arabidopsis thaliana] >gi|7270936|emb|CAB80615.1| (AL161595) GTP-binding-like protein [Arabidopsis thaliana] Length = 369 Score = 224 bits (564), Expect = 2e-57 Identities = 134/369 (36%), Positives = 206/369 (55%), Gaps = 11/369 (2%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS--LAVKK 78 TI +KI+ +E A K+K T +K KLA+LR++L + GGG V K Sbjct: 3 TIMQKIKEIEDEMAKTQKNKATSHHLGLLKAKLAKLRRDLLAPPTKGGGGGAGEGFDVTK 62 Query: 79 EGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGL 138 G +++ LVG P+VGKS LL LTG E A Y FTT IP ++ Y+ +IQL+++PG+ Sbjct: 63 SGDSRVGLVGFPSVGKSTLLNKLTGTFSEVASYEFTTLTCIPGVITYRGAKIQLLDLPGI 122 Query: 139 IEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIE 198 IEGA GKG G Q+++ R + I IV+D + PI +++ +E E GI++NK P + Sbjct: 123 IEGAKDGKGRGRQVISTARTCNCILIVLDAIK-PITHKRLIEKELEGFGIRLNKEPPNLT 181 Query: 199 IRRTPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVW 257 R+ GGI + + D++ V + E ++H+A+IT+R T +D D ++ S ++ Sbjct: 182 FRKKDKGGINLTSTVAVTHLDLDTVKAICGEYRMHNADITLRYDATADDLIDVIEGSRIY 241 Query: 258 KKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVF 317 I NK D+ ++ ++ + PVSA NLD + + +++ ++ R++ Sbjct: 242 MPCIYAVNKIDSITLEE-----LEILDKLPHYCPVSAHLEWNLDGLLDKIWEYLDLTRIY 296 Query: 318 TKSPGEEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375 TK P Y P I + TV D RIHKD++K F+YA VWG S K QRVG +H Sbjct: 297 TKPKAMNPDYDDPVILSSKKRTVEDFCIRIHKDMLKQFKYALVWGSSAKHKPQRVGKEHE 356 Query: 376 LEDGDIVEI 384 LED D+V+I Sbjct: 357 LEDEDVVQI 365 >gb|AAF58591.1| (AE003823) 128up gene product [Drosophila melanogaster] Length = 368 Score = 224 bits (564), Expect = 2e-57 Identities = 138/368 (37%), Positives = 209/368 (56%), Gaps = 10/368 (2%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79 TI EKI A+E A K+K T +K KLA+LR+EL + G G + V K Sbjct: 3 TILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGGGGTGEAGFEVAKT 62 Query: 80 GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139 G A++ VG P+VGKS LL L GV E A Y FTT +P + YK +IQL+++PG+I Sbjct: 63 GDARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGII 122 Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199 EGA GKG G Q++AV R + I +V+D + P+ K+L E E GI++NK+ P I Sbjct: 123 EGAKDGKGRGRQVIAVARTCNLIFMVLDCLK-PLGHKKLLEHELEGFGIRLNKKPPNIYY 181 Query: 200 RRTPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWK 258 +R GGI +N + + D + V +L E KIH+A+IT+R T +D D ++ + ++ Sbjct: 182 KRKDKGGINLNSMVPQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYI 241 Query: 259 KAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318 I + NK D + + E+L Y + +P+SA N D + E +++ + R++T Sbjct: 242 PCIYLLNKID----QISIEELDVIY-KIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYT 296 Query: 319 KSPGEEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376 K G+ P Y P + +++ D ++H+ + K F+YA VWG SVK Q+VG +HVL Sbjct: 297 KPKGQLPDYNSPVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVL 356 Query: 377 EDGDIVEI 384 D D+V+I Sbjct: 357 NDEDVVQI 364 >pir||T43254 GTP-binding protein - Thermoplasma acidophilum >gi|1698846|gb|AAC44620.1| (U72850) GTP-binding protein [Thermoplasma acidophilum] Length = 360 Score = 223 bits (563), Expect = 2e-57 Identities = 135/369 (36%), Positives = 214/369 (57%), Gaps = 14/369 (3%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79 TI E+I+ +E +K TE +K K+A+L+ E GG +S AV K Sbjct: 3 TIEERIKEIEDEIKRTQYNKATEHHIGLLKAKIAKLQMEASASH----GGSHSGFAVPKS 58 Query: 80 GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139 G A + LVG PNVGKS LL LT + E DY FTT +PIP ++ YK +IQ++++PG+I Sbjct: 59 GDATVALVGFPNVGKSSLLNRLTNSESEIGDYAFTTLQPIPGILEYKGAEIQILDLPGII 118 Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199 E A+ G G ++L+ +R AD I IV D+ I + +L E AGI VN++R +EI Sbjct: 119 ENASYGSARGREILSAVRAADLIVIVTDVQAGGIDK---ILTELYNAGIVVNRKRRNVEI 175 Query: 200 RRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259 R+T SGGI ++ +N+ D + + ++++E K+ +A++ +RE V++ED + L V+ Sbjct: 176 RKTTSGGIRLHRPKNVDIDEDYIKEIMKEFKLVNADVYIRENVSVEDIIETLQGRYVYIP 235 Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319 +I+ NK D S D + V YGE F+ VSAK ++ +KE ++ +IR++ + Sbjct: 236 SIVAVNKIDMNPSFDTSQ--VSQYGEVFR---VSAKTGYGIEELKEGIFRSLNLIRIYLR 290 Query: 320 S-PGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378 + G P+ ++ G+TV +V +I++ ++ +FRYA V GK+ RVG D+ L D Sbjct: 291 NKAGVVDFQKPLIVREGTTVREVCRKINRSMIDSFRYAIVSGKNRPIGEHRVGIDYPLMD 350 Query: 379 GDIVEIHAR 387 DIV I +R Sbjct: 351 EDIVTIISR 359 >gi|10946678 developmentally regulated GTP-binding protein 2 [Mus musculus] >gi|8928105|sp|Q9QXB9|DRG2_MOUSE DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN 2 (DRG 2) >gi|6688758|emb|CAB65258.1| (AJ243590) GTP-binding protein [Mus musculus] Length = 364 Score = 221 bits (558), Expect = 9e-57 Identities = 126/365 (34%), Positives = 202/365 (54%), Gaps = 8/365 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I EKI +EK A K+K TE +K KLA+ R +L + + G V K G Sbjct: 3 ILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGD 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 A++ L+G P+VGKS L +T E+A Y FTT IP ++ YK IQL+++PG+IEG Sbjct: 63 ARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 AA G+G G Q++AV R AD + +++D ++ + Q +L +E E GI++NK +P I + Sbjct: 123 AAQGRGRGRQVIAVARTADVVVMMLDATKGDV-QRSLLEKELESVGIRLNKHKPNIYFKP 181 Query: 202 TPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 GGI N + +++++ L E KI +AE+ RE + +DF D + + V+ Sbjct: 182 KKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDDFIDVIVGNRVYMPC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + NK D ++ V + + +S ++NLD + E L++ + ++TK Sbjct: 242 LYVYNKIDQISMEE-----VDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKK 296 Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379 G+ P + I L++G++V V RIH+ L F+YA VWG S K+ QRVG H +E Sbjct: 297 RGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHE 356 Query: 380 DIVEI 384 D+++I Sbjct: 357 DVIQI 361 >gi|4557537 developmentally regulated GTP-binding protein 2 [Homo sapiens] >gi|1706518|sp|P55039|DRG2_HUMAN DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN 2 (DRG 2) >gi|1082424|pir||A55014 GTP-binding protein DRG homolog - human >gi|577779|emb|CAA56730.1| (X80754) GTP-binding protein [Homo sapiens] Length = 364 Score = 221 bits (557), Expect = 1e-56 Identities = 127/365 (34%), Positives = 202/365 (54%), Gaps = 8/365 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I EKI +EK A K+K TE +K KLA+ R +L + + G V K G Sbjct: 3 ILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGD 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 A++ L+G P+VGKS L +T E+A Y FTT IP ++ YK IQL+++PG+IEG Sbjct: 63 ARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 AA GKG G Q++AV R AD I +++D ++ + Q +L +E E GI++NK +P I + Sbjct: 123 AAQGKGRGRQVIAVARTADVIIMMLDATKGEV-QRSLLEKELESVGIRLNKHKPNIYFKP 181 Query: 202 TPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 GGI N + +++++ L E KI +AE+ RE + ++F D + + V+ Sbjct: 182 KKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + NK D ++ V + + +S ++NLD + E L++ + ++TK Sbjct: 242 LYVYNKIDQISMEE-----VDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKK 296 Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379 G+ P + I L++G++V V RIH+ L F+YA VWG S K+ QRVG H +E Sbjct: 297 RGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHE 356 Query: 380 DIVEI 384 D+++I Sbjct: 357 DVIQI 361 >sp|P32234|128U_DROME GTP-BINDING PROTEIN 128UP >gi|422452|pir||S33467 GTP-binding protein 128up - fruit fly (Drosophila melanogaster) >gi|630861|pir||S42582 GTP-binding protein 128up - fruit fly (Drosophila melanogaster) >gi|311343|emb|CAA50701.1| (X71866) GTP-binding protein [Drosophila melanogaster] Length = 368 Score = 220 bits (556), Expect = 2e-56 Identities = 136/368 (36%), Positives = 208/368 (55%), Gaps = 10/368 (2%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79 TI EKI A+E A K+K T +K +A+LR+EL + G G + V K Sbjct: 3 TILEKISAIESEMARTQKNKATSAHLGLLKANVAKLRRELISPKGGGGGTGEAGFEVAKT 62 Query: 80 GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139 G A++ VG P+VGKS LL L GV E A Y FTT +P + YK +IQL+++PG+I Sbjct: 63 GDARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGII 122 Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199 EGA GKG G Q++AV R + I +V+D + P+ K+L E E GI++NK+ P I Sbjct: 123 EGAKDGKGRGRQVIAVARTCNLIFMVLDCLK-PLGHKKLLEHELEGFGIRLNKKPPNIYY 181 Query: 200 RRTPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWK 258 +R GGI +N + + D + V +L E KIH+A+IT+R T +D D ++ + ++ Sbjct: 182 KRKDKGGINLNSMVPQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYI 241 Query: 259 KAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318 I + NK D + + E+L Y + +P+SA N D + E +++ + R++T Sbjct: 242 PCIYLLNKID----QISIEELDVIY-KIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYT 296 Query: 319 KSPGEEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376 K G+ P Y P + +++ D ++H+ + K F+YA VWG SVK Q+VG +HVL Sbjct: 297 KPKGQLPDYNSPVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVL 356 Query: 377 EDGDIVEI 384 D D+V+I Sbjct: 357 NDEDVVQI 364 >gi|6319281 similar to Xenopus GTP-binding protein DRG; Fun11p [Saccharomyces cerevisiae] >gi|731276|sp|P39729|YAD6_YEAST HYPOTHETICAL 40.7 KD PROTEIN IN PYK1-SNC1 INTERGENIC REGION >gi|1077475|pir||S51983 FUN11 protein - yeast (Saccharomyces cerevisiae) >gi|595548|gb|AAC04995.1| (U12980) Fun11p [Saccharomyces cerevisiae] Length = 369 Score = 220 bits (556), Expect = 2e-56 Identities = 136/370 (36%), Positives = 215/370 (57%), Gaps = 12/370 (3%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLA--VKK 78 T EKI+A+E A K+K T Q+K KLA+LR+EL GGG + V + Sbjct: 3 TTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVAR 62 Query: 79 EGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGL 138 G A + VG P+VGKS LL LTG + E+A+Y FTT +P ++ YK +IQ++++PG+ Sbjct: 63 TGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTVPGVIRYKGAKIQMLDLPGI 122 Query: 139 IEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIE 198 I+GA G+G G Q++AV R + + I++D+++ P+ +I+ +E E GI++NK P I Sbjct: 123 IDGAKDGRGRGKQVIAVARTCNLLFIILDVNK-PLHHKQIIEKELEGVGIRLNKTPPDIL 181 Query: 199 IRRTPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALD-ESLV 256 I++ GGI + N + +E+ ++ E +I+SAEI R T++D D L+ S Sbjct: 182 IKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRR 241 Query: 257 WKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRV 316 + AI + NK D+ S + E L + +P+S+ + NLD + + ++D ++R+ Sbjct: 242 YMPAIYVLNKIDSL-SIEELELLYRIP----NAVPISSGQDWNLDELLQVMWDRLNLVRI 296 Query: 317 FTKSPGEEPAY-PPIALKRG-STVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDH 374 +TK G+ P + P+ L+ +V D +IHK LV +FR A V+G SVK Q VG H Sbjct: 297 YTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDDFRNALVYGSSVKHQPQYVGLSH 356 Query: 375 VLEDGDIVEI 384 +LED D+V I Sbjct: 357 ILEDEDVVTI 366 >gb|AAC33135.1| (AF035177) GTP-binding protein [Oncorhynchus tshawytscha] Length = 364 Score = 220 bits (556), Expect = 2e-56 Identities = 127/365 (34%), Positives = 209/365 (56%), Gaps = 8/365 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I EKI +E+ + K+K TE +K KLA+ R +L + + G V K G Sbjct: 3 ILEKIGEIEREISRTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSAGAKGEGFDVMKSGD 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 A++ L+G P+VGKS L +T E+A Y FTT IP ++ Y IQL+++PG+IEG Sbjct: 63 ARVALIGFPSVGKSTFLSLMTATASEAASYEFTTLTCIPGVIEYNGANIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 A+ GKG G Q++AV R AD + +++D ++ + Q K+L +E E GI++N+ +P I + Sbjct: 123 ASQGKGRGRQVIAVARTADVVIMMLDATKGDV-QRKLLEKELESVGIRLNRSKPNIYFKP 181 Query: 202 TPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 GG+ N + + +++++ L E KI +AE+ RE T +DF D + + V+ Sbjct: 182 KKGGGLSYNSMVPLTMCSEKLVQLILHEYKIFNAEVLFREDSTPDDFIDVIVGNRVYMPC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + NK D + + E++ + E ++ +S ++NLD + E L++ +I ++TK Sbjct: 242 LYVYNKVD----QISIEEVDRLAHEPHSVV-ISCGMKLNLDFLLERLWEYLALICLYTKK 296 Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379 GE P + I ++RG++V V RIH+ L F+YA VWG S KF QRVG H++E Sbjct: 297 RGERPDFSDAIIMRRGASVEHVCHRIHRTLASQFKYALVWGTSTKFDPQRVGLTHIMEHE 356 Query: 380 DIVEI 384 D+++I Sbjct: 357 DVIQI 361 >pir||T31553 hypothetical protein T28D6.6 - Caenorhabditis elegans >gi|5832862|emb|CAB55097.1| (AL117202) contains similarity to Pfam domain: PF01018 (GTP1/OBG family), Score=576.0, E-value=7.7e-170, N=1~cDNA EST yk64c12.3 comes from this gene~cDNA EST yk151h4.3 comes from this gene~cDNA EST yk211a3.3 comes from this gene~cDNA EST yk466c6.3 come> >gi|6018399|emb|CAB57908.1| (Z81134) contains similarity to Pfam domain: PF01018 (GTP1/OBG family), Score=576.0, E-value=7.7e-170, N=1~cDNA EST yk64c12.3 comes from this gene~cDNA EST yk151h4.3 comes from this gene~cDNA EST yk211a3.3 comes from this gene~cDNA EST yk466c6.3 comes > Length = 366 Score = 220 bits (555), Expect = 2e-56 Identities = 138/367 (37%), Positives = 210/367 (56%), Gaps = 9/367 (2%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80 ++ +KI +E A K+K T +K KLA+LR++L + G G V K G Sbjct: 2 SVLQKIADIEAEMARTQKNKATNAHLGILKAKLAKLRRDLITPKGGGGGPGEGFDVAKTG 61 Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140 A+I VG P+VGKS LL L GV E A Y FTT +P ++ YK +IQL+++PG+IE Sbjct: 62 DARIGFVGFPSVGKSTLLCNLAGVFSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIE 121 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200 GA GKG G Q++AV R I +V+D+ + P++ K+L E E GI++NK+ P I + Sbjct: 122 GAKDGKGRGKQVIAVARTCSLILMVLDVMK-PLQHKKLLEYELEGFGIRLNKQPPNIGYK 180 Query: 201 RTPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259 R GGI + + + D++ V +L E +IH+A+IT+R T ED D ++ + ++ Sbjct: 181 RKEKGGINLTMLVPQSELDLDLVKSILAEYRIHNADITLRYDATSEDLIDVIEGNRIYIP 240 Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319 I + NK D + + E+L Y +P+SA + N D + E +++ +IR++TK Sbjct: 241 CIYVLNKID----QISIEELDIIY-RIPHTVPISAHHKWNFDDLLEKVWEYLNLIRIYTK 295 Query: 320 SPGEEPAY-PPIALK-RGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377 G+ P Y PI L ++ D+ +IHK L K+F+ A VWG S K QRVG DHVL Sbjct: 296 PKGQLPDYSQPIVLNAERKSIEDLCTKIHKSLQKDFKCALVWGASAKHNPQRVGRDHVLI 355 Query: 378 DGDIVEI 384 D D+V++ Sbjct: 356 DEDVVQV 362 >sp|P17103|YRB1_HALCU HYPOTHETICAL 40 KD GTP-BINDING PROTEIN IN RIBOSOMAL PROTEIN GENE CLUSTER 5'REGION >gi|76329|pir||QQHS4C GTP-binding protein DRG homolog - Halobacterium salinarum (strain cutirubrum) >gi|43450|emb|CAA33176.1| (X15078) ORF protein [Halobacterium cutirubrum] >gi|10580655|gb|AAG19503.1| (AE005042) GTP-binding protein DRG; Drg [Halobacterium sp. NRC-1] Length = 370 Score = 216 bits (544), Expect = 4e-55 Identities = 132/370 (35%), Positives = 205/370 (54%), Gaps = 7/370 (1%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 + E I +LE+ A P +K TE ++K KLAE +++LE Q Q GGG AV++ G Sbjct: 3 LEEDIESLEEEIANTPYNKSTEAHIGRLKAKLAEQKEKLEAQ-QSGSGGGGGYAVEQHGD 61 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 A + LVG P+VGKS L+ A+T D E Y FTT P M+ Y+ IQL++VPGLIEG Sbjct: 62 ATVALVGFPSVGKSSLINAMTNADSEVGAYEFTTLNVNPGMLEYRGANIQLLDVPGLIEG 121 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 AA G+G G ++L+VIR AD + V+ E I+Q L E I+V+ P + +RR Sbjct: 122 AAGGRGGGKEILSVIRGADLVIFVLSAFE--IEQYDRLAEELYNVNIRVDAEPPSVTVRR 179 Query: 202 TPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAI 261 GI +N ++ D + V +LRE +A +T+R +++ D + ++ V+ ++ Sbjct: 180 KGKDGIDVNTSGELELDSDTVKGILRERGFINANVTIRGNPSVDRLIDGVMDNRVYMPSL 239 Query: 262 IIANKGD--APGSKDNYEKLVKAYG-ERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318 + NK D P + ++ +G I +SA + LD +KE ++ +IR++ Sbjct: 240 VTVNKVDLIEPSYAGTMKDALRDHGVSPDDAIFISAAEEKGLDVLKERMWRALGLIRIYM 299 Query: 319 KSPGE-EPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377 PG P+ ++RG TV D +++ L + FR+ARV G S + Q+VG DHVLE Sbjct: 300 DKPGRGVDREEPLIIRRGETVDDAVQKLGGTLDERFRFARVTGPSAQHDDQQVGRDHVLE 359 Query: 378 DGDIVEIHAR 387 D D++ + AR Sbjct: 360 DEDVLRVVAR 369 >gi|6321612 Ygr173wp [Saccharomyces cerevisiae] >gi|1723727|sp|P53295|YG3Y_YEAST HYPOTHETICAL 41.0 KD PROTEIN IN YIP1-CBP4 INTERGENIC REGION >gi|2120158|pir||S64487 GTP-binding protein DRG homolog - yeast (Saccharomyces cerevisiae) >gi|1323306|emb|CAA97199.1| (Z72958) ORF YGR173w [Saccharomyces cerevisiae] Length = 368 Score = 214 bits (539), Expect = 1e-54 Identities = 129/372 (34%), Positives = 210/372 (55%), Gaps = 12/372 (3%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKEG 80 I +KI+A+E+ A K+K TE +K KLA R++L GGG S V K G Sbjct: 3 IIDKIKAIEEEMARTQKNKATEHHLGLLKGKLARYRQQLLADEAGSGGGGGSGFEVAKSG 62 Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140 A++VL+G P+VGKS LL +T E A Y FTT +P ++ Y+ +IQ+V++PG+I Sbjct: 63 DARVVLIGYPSVGKSSLLGKITTTKSEIAHYAFTTLTSVPGVLKYQGAEIQIVDLPGIIY 122 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200 GA+ GKG G Q++A R AD + +V+D ++ Q L +E E GI++NK +P I + Sbjct: 123 GASQGKGRGRQVVATARTADLVLMVLDATKSE-HQRASLEKELENVGIRLNKEKPNIYYK 181 Query: 201 RTPSGGIVINGIENIKGDINE--VMKMLREEKIHSAEITVR-EPVTLEDFADALDES-LV 256 + +GG+ + K ++ E + +LR+ +IH+AE+ VR + T++DF D ++E Sbjct: 182 KKETGGVKVTFTSPPKTNLTEQAIKMILRDYRIHNAEVLVRDDQCTIDDFIDVINEQHRN 241 Query: 257 WKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRV 316 + K + + NK DA S + +KL + + +S + + L V E ++ + RV Sbjct: 242 YVKCLYVYNKIDAV-SLEEVDKLAR----EPNTVVMSCEMDLGLQDVVEEIWYQLNLSRV 296 Query: 317 FTKSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375 +TK G P + P+ ++ ST+ D+ IH+D F+YA VWG S K Q+ G +H Sbjct: 297 YTKKRGVRPVFDDPLVVRNNSTIGDLCHGIHRDFKDKFKYALVWGSSAKHSPQKCGLNHR 356 Query: 376 LEDGDIVEIHAR 387 ++D D+V + A+ Sbjct: 357 IDDEDVVSLFAK 368 >sp|P34280|YKK3_CAEEL HYPOTHETICAL 64.3 KD GTP-BINDING PROTEIN C02F5.3 IN CHROMOSOME III >gi|630509|pir||S44605 C02F5.3 protein - Caenorhabditis elegans >gi|289610|gb|AAA27918.1| (L14745) homology with GTP binding protein; putative [Caenorhabditis elegans] Length = 573 Score = 213 bits (538), Expect = 2e-54 Identities = 124/370 (33%), Positives = 206/370 (55%), Gaps = 10/370 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I EKI +E + K+K TE +K KLA+ R++L + + G V K G Sbjct: 3 ILEKIAEIEHEISRTQKNKATEYHLGLLKAKLAKYRQQLLEPTGKGGAKGEGFDVMKSGD 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 A++ +VG P+VGKS LL ++T E+A Y FTT IP +++Y IQL+++PG+IEG Sbjct: 63 ARVAMVGFPSVGKSTLLSSMTSTHSEAAGYEFTTLTCIPGVISYNGANIQLLDLPGIIEG 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 A+ GKG G Q+++V + AD I +++D + +Q +L RE E GI++NK+ P I +++ Sbjct: 123 ASQGKGRGRQVISVAKTADLILMMLDAGKSD-QQKMLLERELEAVGIRLNKKPPNIYVKQ 181 Query: 202 TPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 GG+ N + + +M +L E KI +A++ RE T+++F D + + V+ Sbjct: 182 KKVGGVKFTNTVPLTHCNEKLIMTVLHEYKIFNADVIFREDCTVDEFIDVIQGNRVYMTC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + NK D S + ++L + + +S + +N+D + E +++ ++RV+TK Sbjct: 242 LYVYNKVDQI-SIEEIDRLARMPHH----VVISCEMNLNMDYLLEKMWEYLALVRVYTKK 296 Query: 321 PGEEPAYPP---IALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377 PG P P I L+ G+T+ +H+ + RYA VWG S KF QRVG H L+ Sbjct: 297 PGNAPDLGPEDGIILRGGATIEHCCHALHRSIAAQLRYAIVWGTSTKFSPQRVGLHHKLD 356 Query: 378 DGDIVEIHAR 387 D+++I R Sbjct: 357 HEDVIQIMRR 366 >gb|AAF77220.1|AC009601_14 (AC009601) L165.8 [Leishmania major] Length = 374 Score = 204 bits (513), Expect = 2e-51 Identities = 122/374 (32%), Positives = 211/374 (55%), Gaps = 18/374 (4%) Query: 24 EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG--GYSLAVKKEGA 81 E+ +A+E+ A K+K TE ++K +LA ++ E+ + + G G V+K G Sbjct: 5 ERRKAIEEEIARTQKNKKTEYHVGRLKGQLARIKTEMMENAARAAGAKAGDGFDVRKSGD 64 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 + LVG P+VGKS L +T + E+A Y FTT IP + +K +IQ++++PG+IEG Sbjct: 65 VRCALVGFPSVGKSSFLSCVTQTESEAAGYEFTTLTCIPGKLMHKGTEIQILDLPGIIEG 124 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 AA GKG G Q++A R AD I +++D ++ ++ KI E E GI++N+R P + ++ Sbjct: 125 AAEGKGRGRQVIATARTADMIILMLDAAKAEAQRSKI-ESELESVGIRLNQRFPNVTFKK 183 Query: 202 TPSGGIVI----NGIENIKGDINEVMK-MLREEKIHSAEITVREPVTLEDFADALDESLV 256 S + + + + +G +++K +L++ I +A++ +RE +T++ F D ++ + Sbjct: 184 KTSCSMNVVSYSSTVPQTRGVSEQMVKEVLKDYGIFNADVALREDITVDQFIDVIEGNRK 243 Query: 257 WKKAIIIANKGD--APGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEII 314 + + + NK D D +L + + +S +N+D V + +++ II Sbjct: 244 YMPCLYVYNKIDTITMEEMDRLSRLPHS-------VVLSLHWDLNVDEVIDEVWEHLNII 296 Query: 315 RVFTKSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPD 373 R++TK GE P + P +KR ++V + +RIHKD+V F+YA VWG S K QRVG Sbjct: 297 RIYTKKHGEHPDFGKPFVVKRDASVEHICKRIHKDIVSRFKYALVWGTSAKHQPQRVGIS 356 Query: 374 HVLEDGDIVEIHAR 387 H LED D+++I R Sbjct: 357 HELEDEDVLQIMLR 370 >sp|P32235|GTP1_SCHPO GTP-BINDING PROTEIN 1 >gi|419815|pir||JT0741 GTP-binding protein 1 - fission yeast (Schizosaccharomyces pombe) >gi|173396|gb|AAA35308.1| (L00671) GTP-binding protein [Schizosaccharomyces pombe] Length = 364 Score = 202 bits (509), Expect = 5e-51 Identities = 124/364 (34%), Positives = 202/364 (55%), Gaps = 10/364 (2%) Query: 24 EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83 EKI+ +E K+K TE +K KLA+LR +L + + G V K G A+ Sbjct: 5 EKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPTSKSGPKGEGFDVLKSGDAR 64 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 + +G P+VGKS LL A+T +A Y FTT IP ++ Y +IQ++++PG+IEGA+ Sbjct: 65 VAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVLEYDGAEIQMLDLPGIIEGAS 124 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSED-PIKQMKILLREFERAGIKVNKRRPRIEIRRT 202 G+G G Q ++ R AD I +V + PI + KI E E+ GI++N++ P + + Sbjct: 125 QGRG-GRQAVSAARTADLILMVFGCYKKLPISEKKIEY-ELEQVGIRLNRQPPNVTLTIK 182 Query: 203 PSGGIVIN-GIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAI 261 +GGI N + D +L E +IH+A+I +RE +T++DF D + + + + Sbjct: 183 KNGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDITVDDFIDLVMGNRRYINCL 242 Query: 262 IIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSP 321 +K DA S + ++L + K + +S ++NLD +KE +++ + R++TK Sbjct: 243 YCYSKIDAV-SLEEVDRLARLP----KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRK 297 Query: 322 GEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380 GE P + + + +GST+ V RIH+ L + +YA VWG S K Q VG +H +E+GD Sbjct: 298 GEMPDFSEALIIHKGSTIEQVCNRIHRTLAEQLKYALVWGTSAKHSPQVVGLNHRVEEGD 357 Query: 381 IVEI 384 +V I Sbjct: 358 VVTI 361 >gi|11427872 developmentally regulated GTP-binding protein 2 [Homo sapiens] Length = 307 Score = 198 bits (498), Expect = 1e-49 Identities = 108/309 (34%), Positives = 176/309 (56%), Gaps = 8/309 (2%) Query: 78 KEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPG 137 K G A++ L+G P+VGKS L +T E+A Y FTT IP ++ YK IQL+++PG Sbjct: 2 KSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPG 61 Query: 138 LIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRI 197 +IEGAA GKG G Q++AV R AD I +++D ++ + Q +L +E E GI++NK +P I Sbjct: 62 IIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEV-QRSLLEKELESVGIRLNKHKPNI 120 Query: 198 EIRRTPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLV 256 + GGI N + +++++ L E KI +AE+ RE + ++F D + + V Sbjct: 121 YFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRV 180 Query: 257 WKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRV 316 + + + NK D ++ V + + +S ++NLD + E L++ + + Sbjct: 181 YMPCLYVYNKIDQISMEE-----VDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCI 235 Query: 317 FTKSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375 +TK G+ P + I L++G++V V RIH+ L F+YA VWG S K+ QRVG H Sbjct: 236 YTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHT 295 Query: 376 LEDGDIVEI 384 +E D+++I Sbjct: 296 MEHEDVIQI 304 >pir||T06251 GTP binding protein - garden pea >gi|2345148|gb|AAB67829.1| (AF014821) developmentally regulated GTP binding protein [Pisum sativum] Length = 399 Score = 194 bits (489), Expect = 1e-48 Identities = 121/368 (32%), Positives = 194/368 (51%), Gaps = 11/368 (2%) Query: 22 IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81 I EKI+ +E A K+K TE Q+K K+A+LR +L + + GGG V K G Sbjct: 3 IIEKIKEIEFEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGSSGGGDGFEVTKFGH 62 Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 ++ L+G P+VGKS LL LTG E+A Y FTT IP + ++ + L+ Sbjct: 63 GRVALIGFPSVGKSTLLTLLTGTHSEAASYEFTTLTCIPGLYTTMILRFSCLIFLELLRV 122 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201 + G Q++AV +++D + +V+D S+ +IL +E E G+++NKR P+I ++ Sbjct: 123 LLKARDCGRQVIAVAKSSDIVLMVLDASKSE-GHRQILTKELEAVGLRLNKRPPQIYFKK 181 Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260 +GGI N + D ++L E KIH+AEI RE T++DF D ++ + + K Sbjct: 182 KKTGGISFNSTMPLTHVDEKLCYQILHEYKIHNAEILFREDATVDDFIDVIEGNRKYMKC 241 Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320 + + N D G D V + + +S ++NLD + ++D ++RV+TK Sbjct: 242 VYVYNLIDVVGIDD-----VDRLPRQPNSVVISCNLKLNLDRLLSRMWDEMGLVRVYTKP 296 Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376 G++P + P+ L + G +V D IH+ LVK+ +Y VWG + Q G HVL Sbjct: 297 QGQQPDFSDPVVLSADRGGCSVEDFCNHIHRSLVKDVKYVLVWGIMARHYPQHCGLSHVL 356 Query: 377 EDGDIVEI 384 D D+V+I Sbjct: 357 RDEDVVQI 364 >emb|CAA19048.2| (AL023587) gtp-binding protein 1. [Schizosaccharomyces pombe] Length = 346 Score = 190 bits (479), Expect = 2e-47 Identities = 116/349 (33%), Positives = 194/349 (55%), Gaps = 9/349 (2%) Query: 24 EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83 EKI+ +E K+K TE +K KLA+LR +L + + G V K G A+ Sbjct: 5 EKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPTSKSGPKGEGFDVLKSGDAR 64 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 + +G P+VGKS LL A+T +A Y FTT IP ++ Y +IQ++++PG+IEGA+ Sbjct: 65 VAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVLEYDGAEIQMLDLPGIIEGAS 124 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203 G+G G Q ++ R AD I +V+D ++ ++ KI E E+ GI++N++ P + + Sbjct: 125 QGRG-GRQAVSAARTADLILMVLDATKAADQREKIEY-ELEQVGIRLNRQPPNVTLTIKK 182 Query: 204 SGGIVIN-GIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262 +GGI N + D +L E +IH+A+I +RE +T++DF D + + + + Sbjct: 183 NGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDITVDDFIDLVMGNRRYINCLY 242 Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322 +K DA S + ++L + K + +S ++NLD +KE +++ + R++TK G Sbjct: 243 CYSKIDAV-SLEEVDRLARLP----KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRKG 297 Query: 323 EEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRV 370 E P + + +++GST+ V RIH+ L + +YA VWG S K Q V Sbjct: 298 EMPDFSEALIVRKGSTIEQVCNRIHRTLAEQLKYALVWGTSAKHSPQVV 346 >pir||T40599 hypothetical protein SPBC649.06 - fission yeast (Schizosaccharomyces pombe) (fragment) Length = 347 Score = 190 bits (479), Expect = 2e-47 Identities = 116/349 (33%), Positives = 194/349 (55%), Gaps = 9/349 (2%) Query: 24 EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83 EKI+ +E K+K TE +K KLA+LR +L + + G V K G A+ Sbjct: 5 EKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPTSKSGPKGEGFDVLKSGDAR 64 Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143 + +G P+VGKS LL A+T +A Y FTT IP ++ Y +IQ++++PG+IEGA+ Sbjct: 65 VAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVLEYDGAEIQMLDLPGIIEGAS 124 Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203 G+G G Q ++ R AD I +V+D ++ ++ KI E E+ GI++N++ P + + Sbjct: 125 QGRG-GRQAVSAARTADLILMVLDATKAADQREKIEY-ELEQVGIRLNRQPPNVTLTIKK 182 Query: 204 SGGIVIN-GIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262 +GGI N + D +L E +IH+A+I +RE +T++DF D + + + + Sbjct: 183 NGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDITVDDFIDLVMGNRRYINCLY 242 Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322 +K DA S + ++L + K + +S ++NLD +KE +++ + R++TK G Sbjct: 243 CYSKIDAV-SLEEVDRLARLP----KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRKG 297 Query: 323 EEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRV 370 E P + + +++GST+ V RIH+ L + +YA VWG S K Q V Sbjct: 298 EMPDFSEALIVRKGSTIEQVCNRIHRTLAEQLKYALVWGTSAKHSPQVV 346 >gb|AAG01361.1|AC068666_8 (AC068666) L165.8 [Leishmania major] Length = 230 Score = 110 bits (273), Expect = 2e-23 Identities = 68/234 (29%), Positives = 129/234 (55%), Gaps = 16/234 (6%) Query: 162 IAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTPSGGIVI----NGIENIKG 217 I +++D ++ ++ KI E E GI++N+R P + ++ S + + + + +G Sbjct: 1 IILMLDAAKAEAQRSKIE-SELESVGIRLNQRFPNVTFKKKTSCSMNVVSYSSTVPQTRG 59 Query: 218 DINEVMK-MLREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSK--D 274 +++K +L++ I +A++ +RE +T++ F D ++ + + + + NK D + D Sbjct: 60 VSEQMVKEVLKDYGIFNADVALREDITVDQFIDVIEGNRKYMPCLYVYNKIDTITMEEMD 119 Query: 275 NYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAY-PPIALK 333 +L + + +S +N+D V + +++ IIR++TK GE P + P +K Sbjct: 120 RLSRLPHS-------VVLSLHWDLNVDEVIDEVWEHLNIIRIYTKKHGEHPDFGKPFVVK 172 Query: 334 RGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHAR 387 R ++V + +RIHKD+V F+YA VWG S K QRVG H LED D+++I R Sbjct: 173 RDASVEHICKRIHKDIVSRFKYALVWGTSAKHQPQRVGISHELEDEDVLQIMLR 226 >emb|CAA74319.1| (Y13986) GTP-binding protein [Ostertagia circumcincta] Length = 140 Score = 104 bits (256), Expect = 2e-21 Identities = 60/139 (43%), Positives = 82/139 (58%) Query: 21 TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80 +I +KI+ +E A K+K T +K K A+LR+EL + GGG V K G Sbjct: 2 SILQKIQDIEDEMARTQKNKATNAHLGMLKAKWAKLRQELIAPKGGGGGGGEGFDVAKTG 61 Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140 A++ VG P+VGKS LL L GV E A Y FTT +P ++ YK +IQL+++PG+IE Sbjct: 62 DARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIE 121 Query: 141 GAALGKGMGPQLLAVIRNA 159 GA GKG G Q++AV A Sbjct: 122 GAKDGKGRGKQVIAVALRA 140 >pir||G72586 hypothetical protein APE1164 - Aeropyrum pernix (strain K1) >gi|5104835|dbj|BAA80149.1| (AP000061) 410aa long hypothetical protein [Aeropyrum pernix] Length = 410 Score = 99.1 bits (243), Expect = 8e-20 Identities = 114/418 (27%), Positives = 179/418 (42%), Gaps = 127/418 (30%) Query: 80 GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP-----------------IP-- 120 G+ + LVG NVGKS A T V V+ + PF T EP +P Sbjct: 4 GSIVLGLVGKTNVGKSTFFAAATEVPVKIENRPFVTIEPNVGVGYARKRCAHVELGLPRC 63 Query: 121 ------AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL------ 168 + ++ + ++L++V GL+ GA G+G+G + L +R ADA+ +V+D Sbjct: 64 DPVNSLCIEGWRFIPVKLLDVAGLVPGAHRGRGLGNRFLDDVRKADALLLVVDASGSTDP 123 Query: 169 --------SEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTPSGGIV---------ING 211 S DP++++ ++L E ++ R RR + G V ++G Sbjct: 124 EGVPVKPGSYDPVEEVGLMLGEIYEWMLQNLARDWERFARRVDTAGNVDLVTALSQRLSG 183 Query: 212 IENIKGDINEVMKM--LREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDA 269 E +G + V++ L E+++ S RE + L F + E K A+I+ANK D Sbjct: 184 FEIPRGVVAGVLEETGLGEKRLSSWS---REDLRL--FVKLVLER--GKPAVILANKVDV 236 Query: 270 PGSKDNYEKLVKAYGERFKIIPVSAKKRINL----------------------------- 300 PG+++N E+L +Y ++P SA + L Sbjct: 237 PGAEENVERLGSSY-PGIPVVPASALAELMLRRLAREGRVRYIPGDPDFTVKDPGGLGGK 295 Query: 301 ----------------------DAVKEALYDVAEIIRVFTKSPGEEP---------AYPP 329 A+ A++DV ++I V+ P E+P P Sbjct: 296 ALKALELVRERVMKRWGGTGVVQAINTAVFDVLDMIAVY---PVEDPNRYTDREGRILPD 352 Query: 330 IAL-KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHA 386 + L KRGST D+A RIH DL K F YA V K+ QRVG + L+DGD+V+I A Sbjct: 353 VILVKRGSTPRDLAYRIHTDLGKTFLYA-VNAKT----KQRVGEGYRLQDGDVVKIVA 405 >pir||T42690 hypothetical protein DKFZp434N1827.1 - human (fragment) >gi|6453535|emb|CAB61403.1| (AL133085) hypothetical protein [Homo sapiens] Length = 150 Score = 98.7 bits (242), Expect = 1e-19 Identities = 56/152 (36%), Positives = 89/152 (57%), Gaps = 7/152 (4%) Query: 235 EITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSA 294 ++T+R T +D D ++ + V+ I + NK D + + E+L Y +P+SA Sbjct: 1 DVTLRSDATADDLIDVVEGNRVYIPCIYVLNKID----QISIEELDIIYKVPH-CVPISA 55 Query: 295 KKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYP-PIALKRG-STVLDVAERIHKDLVKN 352 R N D + E ++D +++R++TK G+ P Y P+ L +TV D +IHK+L+K Sbjct: 56 HHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKE 115 Query: 353 FRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384 F+YA VWG SVK Q+VG DH LED D+++I Sbjct: 116 FKYALVWGLSVKHNPQKVGKDHTLEDEDVIQI 147 >pir||C64466 GTP-binding protein - Methanococcus jannaschii >gi|1591973|gb|AAB99340.1| (U67573) GTP-binding protein, member of GTP1/OBG-family [Methanococcus jannaschii] Length = 393 Score = 96.3 bits (236), Expect = 5e-19 Identities = 103/402 (25%), Positives = 166/402 (40%), Gaps = 114/402 (28%) Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTT----------TEPIPA---------- 121 A I LVG PNVGKS + ALT E +YPFTT T P P Sbjct: 2 AMIGLVGKPNVGKSTMFNALTEKPAEIGNYPFTTIQPNKGIAYITSPCPCKELGVKCNPR 61 Query: 122 ----MMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS-------- 169 + + + +++++V GL+ GA G+GMG + L +R ADA +V+D S Sbjct: 62 NSKCIDGIRHIPVEVIDVAGLVPGAHEGRGMGNKFLDDLRQADAFILVVDASGKTDAEGN 121 Query: 170 ----EDPIKQMKILLREFERAGIKV-NKRRPRIEIRRTPSGGIV------INGIENIKGD 218 DP++ +K LL E + + K ++ R IV ++G+ + D Sbjct: 122 PTENYDPVEDVKFLLNEIDMWIYSILTKNWDKLARRAQQEKNIVKALKDQLSGLNIDEDD 181 Query: 219 INEVMKMLREEKIHSAEITVREPVTLEDFAD-ALDESLVWKKAIIIANKGDAPGSKDNYE 277 I ++ + E I E ED + A + K II ANK D P ++ N E Sbjct: 182 IKMAIRDMDESPIKWTE---------EDLLNLAKKLRKISKPMIIAANKADHPDAEKNIE 232 Query: 278 KLVKAYGERFKIIPVSAKKRINL------------------------------------- 300 +L K + + + +IP SA+ + L Sbjct: 233 RLKKEFKD-YIVIPTSAEIELALKRAEKAGIIKRKENDFEIIDESKVNEQMRRAFDYIKD 291 Query: 301 -----------DAVKEALYDVAEIIRVF-----TKSPGEEPAYPPIA--LKRGSTVLDVA 342 + + +A +D+ ++I V+ K ++ P A +K+GST D+A Sbjct: 292 FLKKYGGTGVQECINKAYFDLLDMIVVYPVEDENKFSDKQGNVLPDAFLVKKGSTARDLA 351 Query: 343 ERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384 ++H +L + F YA K + RVG D+ L+ DI++I Sbjct: 352 YKVHTELGEKFIYAIDAKKKI-----RVGADYELKHNDIIKI 388 >pir||C75402 conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6459140|gb|AAF10955.1|AE001984_5 (AE001984) conserved hypothetical protein [Deinococcus radiodurans] Length = 365 Score = 88.5 bits (216), Expect = 1e-16 Identities = 90/373 (24%), Positives = 156/373 (41%), Gaps = 88/373 (23%) Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ-------------- 129 I +VGLPNVGKS L A+T +A+YPF T EP + D + Sbjct: 5 IGIVGLPNVGKSTLFNAITRAGALAANYPFATIEPNVGRVTVPDERLSALSQVFTKGERV 64 Query: 130 -------IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLRE 182 ++ V++ GL++GA+ G+G+G Q LA IR DAIA V+ EDP Sbjct: 65 PPIIPTFVEFVDIAGLVKGASQGEGLGNQFLANIREVDAIAHVVRCFEDPNV-------- 116 Query: 183 FERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLR------EEKIHSAEI 236 + V R ++ T + +++ + ++ + K + +E++ AE Sbjct: 117 -----VHVAGRVDPLDDIETINTELILADLAGLEKRAQNLQKKAKGGDKDAKEQLELAEQ 171 Query: 237 TVR-----EPVTLEDFADALDES---LVWKKAIIIANKGDAPGSKDN-YEKLVKAYG--E 285 ++ +P + + + + K I +AN G+ + DN Y + V+ Y E Sbjct: 172 IIQVLGEGKPARAGSYEGKIPKDFGLITIKPVIYVANVGEDDLTGDNEYVQKVREYAAAE 231 Query: 286 RFKIIPVSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGE 323 +++ +SA+ + LD + + Y+ +I T E Sbjct: 232 GAQVVKISAQIEGELAEMPEDEAAAFLHDLGVEESGLDQLVKVGYETLGLITFITSGEKE 291 Query: 324 EPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPG----------QRVG 371 A+ +++G + A IH DL + F A V W K V+ G + G Sbjct: 292 VRAW---TIRKGEKAPEAAGEIHSDLERGFIRAEVIEWQKMVEAGGWAPAKAKGWVRTEG 348 Query: 372 PDHVLEDGDIVEI 384 D+V++DGDI+ + Sbjct: 349 KDYVMQDGDIMNV 361 >pir||H71165 probable GTP-binding protein - Pyrococcus horikoshii >gi|3256930|dbj|BAA29613.1| (AP000002) 397aa long hypothetical GTP-binding protein [Pyrococcus horikoshii] Length = 397 Score = 87.8 bits (214), Expect = 2e-16 Identities = 107/402 (26%), Positives = 169/402 (41%), Gaps = 111/402 (27%) Query: 83 QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTE--------------------PIPAM 122 +I +VG PNVGKS A T VDVE A+YPFTT E P P Sbjct: 2 EIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTIEANVGVTYAITDHPCKELGCSPNPQN 61 Query: 123 MNYKD----VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS--------- 169 Y++ + +++V+V GL+ GA G+G+G + L +R A A+ V+D + Sbjct: 62 YEYRNGLALIPVKMVDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVVDATGKTDPEGQP 121 Query: 170 ---EDPIKQMKILLREFERAGIKV-----NKRRPRIEIRRTPSGGIVINGIENIKGDINE 221 DP++ ++ L RE + + +K RI++++ + + I + N+ Sbjct: 122 TDYHDPVEDIEFLEREIDYWIYGILSKGWDKFAKRIKLQKIKLESAIAEHLSGIGVNEND 181 Query: 222 VMKMLREEKIHSAEITVREPVTLED--FADALDESLVWKKAIIIANKGDAPGSKDNYEKL 279 V E +H + +D A A + V K +I ANK DA S + ++L Sbjct: 182 VW-----EAMHKLNLPEDPTKWSQDDLLAFASEIRRVNKPMVIAANKADA-ASDEQIKRL 235 Query: 280 VKAYGER-FKIIPVSA--------------------------------KKRINLDAVKEA 306 V+ +R + +IP SA K++ L +KE Sbjct: 236 VREEEKRGYIVIPTSAAAELTLRKAAKAGFIEYIPGASEFKVLRDMSEKQKRALMVIKEK 295 Query: 307 LYD------VAEII-RVFTKSPGEEPAYP-----------------PIALKRGSTVLDVA 342 + D V E+I RV P YP +K+GST D+A Sbjct: 296 VLDRFGSTGVQEVINRVVFDLLKLIPVYPVHDENKLTDQFGNVLPHVFLMKKGSTPRDLA 355 Query: 343 ERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384 ++H DL K F YA + ++ + RVG D+ L+ DIV+I Sbjct: 356 FKVHTDLGKGFLYA-INARTKR----RVGEDYELQFNDIVKI 392 >pir||H75066 GTP-binding protein PAB1357 - Pyrococcus abyssi (strain Orsay) >gi|5458942|emb|CAB50429.1| (AJ248287) GTP-BINDING PROTEIN [Pyrococcus abyssi] Length = 397 Score = 87.0 bits (212), Expect = 3e-16 Identities = 101/402 (25%), Positives = 169/402 (41%), Gaps = 107/402 (26%) Query: 83 QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTE--------------------PIPAM 122 +I +VG PNVGKS A T VDVE A+YPFTT + P P Sbjct: 2 EIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTIDANVGVTYAIAEHPCKELGCKPNPQN 61 Query: 123 MNYKD----VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL---------- 168 Y++ + +++++V GL+ GA G+G+G + L +R A A+ V+D+ Sbjct: 62 YEYREGLALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVVDVTGKTDAEGQP 121 Query: 169 --SEDPIKQMKILLREFERAGIKV-----NKRRPRIEIRRTPSGGIVINGIENIKGDINE 221 + DPI+ ++ L RE + + +K RI+++R + + I N+ Sbjct: 122 TENHDPIEDIEFLEREIDYWIYGILSKGWDKFAKRIKLQRIKLESAIAEHLSGIGVTEND 181 Query: 222 VMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVK 281 V + + + S + T+ L FA + + K II ANK DA S++ +L+K Sbjct: 182 VWEAMHRLGLPS-DPTLWSQEDLLAFASEIRR--INKPMIIAANKADA-ASEEQINRLIK 237 Query: 282 AYGER-FKIIPVSAKKRINL-------------------------DAVKEALYDVAEIIR 315 +R + ++P SA + L + K+AL + E + Sbjct: 238 EGEKRGYIVVPTSAAAELTLRKAAKAGFIDYIPGSSEFKILKDMNERQKKALLMIKEKVL 297 Query: 316 VFTKSPGEE--------------PAYP-----------------PIALKRGSTVLDVAER 344 S G + P YP +K+GS D+A + Sbjct: 298 DRFGSTGVQEVINKAVFELLNLIPVYPVQDENKLTDQFGNVLPHVFLMKKGSNPRDLAFK 357 Query: 345 IHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHA 386 +H DL + F YA + K+ + R+G D+ L+ DI++I A Sbjct: 358 VHTDLGRGFLYA-INAKTKR----RIGEDYELQFNDIIKIVA 394 >pir||E70354 probable GTP-binding protein - Aquifex aeolicus >gi|2983235|gb|AAC06832.1| (AE000698) hypothetical protein [Aquifex aeolicus] Length = 370 Score = 87.0 bits (212), Expect = 3e-16 Identities = 100/368 (27%), Positives = 168/368 (45%), Gaps = 81/368 (22%) Query: 86 LVGLPNVGKSELLRALTG-VDVESADYPFTTTEP------IPAMMNYKDVQIQ------- 131 +VGLPNVGKS L ALT + ++A+YPF T EP +P YK +I+ Sbjct: 7 IVGLPNVGKSTLFNALTKTMKAQAANYPFCTIEPNVGVVEVPDERLYKLAEIEKSQKITP 66 Query: 132 ----LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIV-----------IDLSEDPIKQM 176 V++ GL++GA+ G+G+G Q L+ IR DA+A+V ++ S DP++ Sbjct: 67 TFIEFVDIAGLVKGASKGEGLGNQFLSHIREVDAVAMVLRAFEDENIVHVEGSVDPVRDK 126 Query: 177 KILLREFERAGIKVNKRRPRIE-IRRTPSGG--IVINGIENIKGDINEVMKMLREEKIHS 233 +I+ E E + RIE +++ GG +E++ + E+++ L + ++ Sbjct: 127 EIV--EIELIAKDLESVNRRIEKVQKVAKGGDKKAREEMEHLNA-LKEILENLEPIRKYA 183 Query: 234 AEITVREPVTLEDFADALDESLVWKKAIIIAN--KGDAPGSKDN-YEKLVK--AYGERFK 288 ++ P TLE +A L K + IAN + D P + N + + +K A E Sbjct: 184 DKL---PPETLE-YAKKTLFLLTVKPVMYIANISEKDLPEGEGNPHVERIKEMANQENAP 239 Query: 289 IIPVSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPA 326 ++ +SA+ K L+ V Y + ++I FT E A Sbjct: 240 VVVISAELEAQLAGLSEEEQKEMLEAYGLKEPGLNKVIRTGYRLLDLITFFTAGEREARA 299 Query: 327 YPPIALKRGSTVLDVAERIHKDLVKNFRYARV-----------WGKSVKFPGQRV-GPDH 374 + +KRG+ A +IH D+ + F A V W K+ + R+ G D+ Sbjct: 300 W---TVKRGTKAPQAAGKIHSDMERGFIAAEVISYEDLIKAGSWAKAKEQGLIRLEGKDY 356 Query: 375 VLEDGDIV 382 ++DGD+V Sbjct: 357 EIQDGDVV 364 >gb|AAF97355.1| (AY005820) Obg-like protein [Thermococcus zilligii] Length = 397 Score = 84.7 bits (206), Expect = 2e-15 Identities = 102/404 (25%), Positives = 166/404 (40%), Gaps = 111/404 (27%) Query: 83 QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTE--------------------PIPAM 122 ++ +VG PNVGKS A T VDV+ A+YPFTT E P P Sbjct: 2 EVGVVGKPNVGKSTFFSAATLVDVDIANYPFTTIEANVGVTYAIADHPCKELGCRPNPQN 61 Query: 123 MNYKD----VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS--------- 169 YKD + +++++V GL+ GA G+G+G + L +R A A+ VID + Sbjct: 62 YEYKDGTALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVIDATGKTDAEGQP 121 Query: 170 ---EDPIKQMKILLREFERAGIKVNKR-----RPRIEIRRTPSGGIVINGIENIKGDINE 221 DP++ ++ L RE + + + K+ RI+++ + + + I + Sbjct: 122 TDHHDPVEDIEFLEREIDYWMLGILKKGWEKFAKRIKLQHMKLEQAIADHLSGIGVKEED 181 Query: 222 VMKMLREEKIHSAEITVREPVTLEDFADALDESL--VWKKAIIIANKGDAPGSKDNYEKL 279 V E IH + +D AL L + K II ANK DA S + E+L Sbjct: 182 VW-----EAIHRLGLGDDPTKWTDDELFALVRELRKINKPMIIAANKADA-ASDEQIERL 235 Query: 280 VKAYGER-FKIIPVSAKKRINL-------------------------------------- 300 K +R + +IP SA + L Sbjct: 236 KKEGEKRGYLVIPTSAAAELTLRKAARAGFIDYIPGSSDFRILKEMNPQQEKALQLIKER 295 Query: 301 -----------DAVKEALYDVAEIIRVFTKSPGEE------PAYPPI-ALKRGSTVLDVA 342 + + A++++ ++I V+ + P + L +GST D+A Sbjct: 296 VLERFGSTGVQEVINRAVFELLKLIPVYPVQDENKLTDQFGNVLPHVYLLPKGSTPRDLA 355 Query: 343 ERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHA 386 ++H DL + F YA V ++ +RVG D+ LE DI++I A Sbjct: 356 YKVHTDLGRTFLYA-VNART----HRRVGDDYKLEFNDIIKIVA 394 >dbj|BAB07770.1| (AP001520) GTP-binding protein [Bacillus halodurans] Length = 366 Score = 84.3 bits (205), Expect = 2e-15 Identities = 95/368 (25%), Positives = 155/368 (41%), Gaps = 85/368 (23%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQ-------------- 131 +VGLPNVGKS L A+T ESA+YPF T +P ++ D ++Q Sbjct: 7 IVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDPRLQKLTELVNPKKTVPT 66 Query: 132 ---LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL-----------SEDPIKQMK 177 ++ G++EGA+ G+G+G Q L+ IR DAI+ V+ S DPI+ + Sbjct: 67 AFEFTDIAGIVEGASKGEGLGNQFLSHIRQVDAISHVVRCFDDENITHVSGSVDPIRDIS 126 Query: 178 ILLREFERAGIK-VNKRRPRIE-IRRTPSGGIV--INGIENIKGDINEVMKMLREEKIHS 233 ++ E A ++ V+KR R++ + +T V + +E +K E+ S Sbjct: 127 VINLELILADLESVDKRFSRVQKLAKTKDKEAVAELEVLEKLKDAFE------NEKPARS 180 Query: 234 AEITVREPVTLEDFADALDESLVWKKAIIIAN--KGDAPGSKDN-YEKLVKAYG--ERFK 288 E T + ++ L K + +AN + D DN + + VKA+ E + Sbjct: 181 IEFTEEQQKIVKGL-----HLLTSKPVLYVANVSEDDVLSPDDNPFVQKVKAFAAEENSE 235 Query: 289 IIPVSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPA 326 +I VSAK + LD + A Y + + FT E A Sbjct: 236 VIVVSAKIEEEIAELDGEEKAMFLEELGIQESGLDQLIRAAYSLLGLQTYFTAGEQEVRA 295 Query: 327 YPPIALKRGSTVLDVAERIHKDLVKNFRYAR-------VWGKSVKFPGQR-----VGPDH 374 + ++G+ A IH D K F A V S+ +R G ++ Sbjct: 296 W---TFRKGTKAPQAAGIIHSDFEKGFIRAETVSYNDLVEAGSMAVAKERGKVRLEGKEY 352 Query: 375 VLEDGDIV 382 V++DGD++ Sbjct: 353 VVQDGDVI 360 >sp|P47270|Y024_MYCGE PROBABLE GTP-BINDING PROTEIN MG024 >gi|1361525|pir||F64202 probable GTP-binding protein - Mycoplasma genitalium >gi|3844633|gb|AAC71240.1| (U39681) GTP-binding protein, putative [Mycoplasma genitalium] Length = 367 Score = 83.1 bits (202), Expect = 5e-15 Identities = 88/358 (24%), Positives = 150/358 (41%), Gaps = 66/358 (18%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130 +VGLPNVGKS L A+T + VE A+YPF T EP ++N D ++ Sbjct: 6 IVGLPNVGKSTLFSAITNLQVEIANYPFATIEPNTGIVNVSDERLDKLASLINPEKIVYT 65 Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177 + V++ GL++GA+ G+G+G Q LA IR D I V+ + DP+ + Sbjct: 66 TFRFVDIAGLVKGASQGQGLGNQFLANIREVDLICHVVRCFQDKKIVHVNNTIDPVFDFE 125 Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGG-----------IVINGIENIKGDINEVMKML 226 I++ E +A ++ R R+ SG IV+NG++ + I + + Sbjct: 126 IIVNELIQADFELITNRIGKLKRKAESGDKIAKEEFVLLEIVLNGLKQGQMPI-QTLSES 184 Query: 227 REEKIHSAEITVREPVTL-----EDFADALDESLVWKKAIIIANKGDAPGSKDNYEKL-- 279 + I S + +P+ + E+ LD + KK ++ P + + Sbjct: 185 ELKTIKSLNLLTAKPILIVANVSENDLLNLDNNEALKKLNAFLDQKKIPKAITVCSLIEK 244 Query: 280 ----VKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRG 335 +K ++ + + K L+ V +A Y + FT E A+ K+G Sbjct: 245 ELSGLKLEQRQYFLDELGLKNYSGLNRVIQAAYQTLNLWSFFTFGKKEVRAW---TFKKG 301 Query: 336 STVLDVAERIHKDLVKNFRYARV--WG--------KSVKFPG--QRVGPDHVLEDGDI 381 A +IH D K F V W + K G + G +++++DGD+ Sbjct: 302 WNAPQCAGQIHSDFEKGFIKVEVISWDQLFAMKSLQEAKKQGLIRLEGKNYLIKDGDV 359 >pir||B72418 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4980588|gb|AAD35192.1|AE001696_6 (AE001696) conserved hypothetical protein [Thermotoga maritima] Length = 435 Score = 82.7 bits (201), Expect = 6e-15 Identities = 74/244 (30%), Positives = 120/244 (48%), Gaps = 30/244 (12%) Query: 68 KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127 KG L ++ + A + LVG PNVGKS L+ ++ + A+YPFTT P ++ Y D Sbjct: 151 KGESRWLELELKILADVGLVGYPNVGKSSLISRISNARPKIANYPFTTLIPNLGVVKYDD 210 Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKILLREF 183 + ++PGLIEGA+ G G+G L + IA VID+S EDP++ ++ E Sbjct: 211 FSFVVADIPGLIEGASEGVGLGNVFLRHVERCYLIAHVIDVSGYEREDPVRDYFVIREEM 270 Query: 184 ERAGIKVNKRRPRIEIRRTPSGGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPV 242 ++ +P I +V N I+ I K ++ +++K LR + T RE + Sbjct: 271 KKYS-PFLLEKPEI---------VVANKIDLIGKEELEKILKRLR-------DATNREVI 313 Query: 243 TLEDFADALDESLVWKKAIIIAN-KGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLD 301 + + LV K A I+ K + P K+ EK VK ++ +P ++ +L+ Sbjct: 314 PVSAVTGEGIDLLVSKLASIVREMKVEKPERKE--EKFVKP-SPVWRRLP----EKFHLE 366 Query: 302 AVKE 305 VKE Sbjct: 367 VVKE 370 >pir||G82870 GTP-binding protein UU595 [imported] - Ureaplasma urealyticum >gi|6899606|gb|AAF31009.1|AE002158_7 (AE002158) GTP-binding protein [Ureaplasma urealyticum] Length = 368 Score = 82.3 bits (200), Expect = 8e-15 Identities = 90/356 (25%), Positives = 151/356 (42%), Gaps = 63/356 (17%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130 LVGLPNVGKS L +T VE+A+YPF T EP ++N D ++ Sbjct: 7 LVGLPNVGKSTLFNTITNSRVEAANYPFATIEPNIGIVNINDPRLKRLASLVVPDKIVPT 66 Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177 + V++ GL++GA+ G+G+G Q L IR+ DAI V+ + D + + Sbjct: 67 TFKFVDIAGLVKGASQGEGLGNQFLNNIRDVDAICHVVRCFDDKSITHVHNKIDALSDIH 126 Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGG-------IVINGIENI--KGDINEVMKMLRE 228 ++ E + + + ++R ++ SG +++ IE KG + +K+ +E Sbjct: 127 VINYELILSDLDIIEKRISRIKKKADSGDKDARREYLILFNIEEALKKGQLASSVKLTKE 186 Query: 229 EK--IHSAEITVREPVTL-----EDFADALDESLVWKKAIIIANKGDAP----GSKDNYE 277 E I+S + +P+ E+ D + + K A DA +K YE Sbjct: 187 ELKIINSFNLITLKPILYIANISENEISNPDLNKEYLKVKKYAQDNDARCVALSAKIEYE 246 Query: 278 KLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGST 337 + + I K LD + + YD+ + FT E A+ I G + Sbjct: 247 ISILDEESKSIFIQDLGIKTTGLDEIVKQTYDLLNLKTYFTYGKQEVRAWTFI---NGMS 303 Query: 338 VLDVAERIHKDLVKNFRYARVW----------GKSVKFPG--QRVGPDHVLEDGDI 381 + A IH D K F A + ++VK G + G ++++DGDI Sbjct: 304 APECAGIIHSDFEKGFIKAEIMHYDDLISLGSEQAVKEAGKIRMEGKSYLMKDGDI 359 >pir||D70197 GTP-binding protein obg - Lyme disease spirochete >gi|2688719|gb|AAC67127.1| (AE001177) GTP-binding protein (obg) [Borrelia burgdorferi] Length = 328 Score = 79.6 bits (193), Expect = 6e-14 Identities = 50/128 (39%), Positives = 74/128 (57%), Gaps = 4/128 (3%) Query: 71 GYSLAVKKEG--AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDV 128 G SL+V+ E A I LVGLPN GKS LL +T A+YPFTT P M+ Sbjct: 148 GNSLSVRLELFLVADIGLVGLPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGMLRRSYD 207 Query: 129 QIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-DPIKQMKILLREFERAG 187 + + ++PG+I+GA+ G G+G + L I +A+VID+SE + ++ ILL E + Sbjct: 208 DLIIADIPGIIKGASFGVGLGTKFLKHIAKTKILALVIDISEANFLESYNILLNELKSYS 267 Query: 188 IKV-NKRR 194 K+ NK++ Sbjct: 268 HKLFNKKK 275 >pir||T40281 gtp-binding protein 1 - fission yeast (Schizosaccharomyces pombe) >gi|2950451|emb|CAA17801.1| (AL022071) gtp-binding protein 1 [Schizosaccharomyces pombe] Length = 135 Score = 79.6 bits (193), Expect = 6e-14 Identities = 37/98 (37%), Positives = 61/98 (61%), Gaps = 1/98 (1%) Query: 288 KIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPP-IALKRGSTVLDVAERIH 346 K + +S ++NLD +KE +++ + R++TK GE P + + +++GST+ V RIH Sbjct: 35 KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRKGEMPDFSEALIVRKGSTIEQVCNRIH 94 Query: 347 KDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384 + L + +YA VWG S K Q VG +H +E+GD+V I Sbjct: 95 RTLAEQLKYALVWGTSAKHSPQVVGLNHRVEEGDVVTI 132 >pir||A64591 probable GTP-binding protein gtp1 - Helicobacter pylori (strain 26695) >gi|2313689|gb|AAD07637.1| (AE000571) GTP-binding protein (gtp1) [Helicobacter pylori 26695] Length = 366 Score = 79.2 bits (192), Expect = 7e-14 Identities = 94/369 (25%), Positives = 159/369 (42%), Gaps = 87/369 (23%) Query: 86 LVGLPNVGKSELLRALTGV-DVESADYPFTTTEPIPAMMNYKDVQ--------------- 129 +VGLPNVGKS ALT + +SA+YPF T EP A++N D + Sbjct: 7 IVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILH 66 Query: 130 --IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQM 176 ++ V++ GLI+GA+ G+G+G Q LA I+ + I V+ E DP+ + Sbjct: 67 SVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKIDPLNDI 126 Query: 177 KILLREFERAGI-KVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAE 235 + + E A I ++KR R++ +++ K D +++ K H E Sbjct: 127 ETIELELILADIAALDKRIDRLQ-----------KALKSSK-DAKNLLECALSLKTHLEE 174 Query: 236 ITVRE--PVTLEDFADALDESLVW---KKAIIIANKGDAP-GSKDNYEKLVK--AYGERF 287 + + P+ + LD+ L + KK I +AN G+ + + + K VK A + Sbjct: 175 LKPAKTFPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNALNEHAKKVKNHAKEQNS 234 Query: 288 KIIPVSAKKRINL-----DAVKEALYDVA-----------------EIIRVFTKSPGEEP 325 + + + AK + D VKE L + +I FT E Sbjct: 235 EFVALCAKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVR 294 Query: 326 AYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPD 373 ++ +K+GS+ A IHKD K F A + + + G+ G D Sbjct: 295 SW---TIKKGSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKD 351 Query: 374 HVLEDGDIV 382 ++++DGD++ Sbjct: 352 YIVQDGDVL 360 >pir||A72280 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981794|gb|AAD36315.1|AE001779_17 (AE001779) conserved hypothetical protein [Thermotoga maritima] Length = 357 Score = 79.2 bits (192), Expect = 7e-14 Identities = 87/372 (23%), Positives = 153/372 (40%), Gaps = 98/372 (26%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQL------------- 132 +VGLPN GKS LT V + +PF T EP ++ D +I++ Sbjct: 3 IVGLPNAGKSSFFNFLTDNSVPAESFPFCTIEPNVGILVVPDERIEILAKNEGSKKVVHP 62 Query: 133 ----VEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED----------------P 172 V++ GL++GA+ G+G+G Q L I D IA V+ L ED Sbjct: 63 FVEVVDIAGLVKGASKGEGLGNQFLDHISKVDVIAHVVRLFEDGRVSHPYQNVDPKRDIE 122 Query: 173 IKQMKILLREFERAGIKVNKRRPRIEIRRT--PSGGIVINGIENIKGDINEVMK------ 224 I + +++L++ E ++ K R+++ RT + ++N++ +++ K Sbjct: 123 IVETELILKDLETVQKRLEK---RMKVARTGDKEAKREVELLQNLREFLSQGKKASKFPR 179 Query: 225 --MLREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKA 282 EE I S + +P L D LDE K+ +I E++VK Sbjct: 180 HDRFEEEVIESLFLLTDKPQILVFNVDELDEE---KRKLI--------------EEIVKE 222 Query: 283 YGERFKIIPVSAKKRINLDAVKEA--------------------LYDVAEIIRVFTKSPG 322 E + II V ++ + +EA + + +IR T + Sbjct: 223 KDEEYIIINVKLEEELKFLPEEEAEVFRREYNLFGDKRKEFFEKVLKLLNLIRFLTATQN 282 Query: 323 EEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPG----------QRV 370 E ++ +K+GST + A IH D+ K F V + + V+F + Sbjct: 283 EARSW---TIKKGSTAYEAAGLIHSDIQKGFIKVEVIPFERYVEFGSLKKAREAGAVETH 339 Query: 371 GPDHVLEDGDIV 382 G D+++ +GD++ Sbjct: 340 GKDYIVREGDVI 351 >pir||B75563 GTP-binding protein Obg - Deinococcus radiodurans (strain R1) >gi|6457748|gb|AAF09676.1|AE001871_8 (AE001871) GTP-binding protein Obg [Deinococcus radiodurans] Length = 438 Score = 78.8 bits (191), Expect = 1e-13 Identities = 41/108 (37%), Positives = 64/108 (58%), Gaps = 7/108 (6%) Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ-------IQLVE 134 A + LVG PN GKS LL AL+ + ADYPFTT PI ++ +D Q + + Sbjct: 160 ADVGLVGYPNAGKSSLLAALSRANPAIADYPFTTLSPILGVVQREDEQGVSLDERFTMAD 219 Query: 135 VPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLRE 182 +PG+IEGA+ GKG+G + L I + V+D++ +P+++++ L E Sbjct: 220 IPGIIEGASEGKGLGLEFLRHISRTRLLVYVLDVTRNPVEELQQLQAE 267 >sp|P75088|Y024_MYCPN PROBABLE GTP-BINDING PROTEIN MG024 HOMOLOG (B01_ORF362) >gi|2146318|pir||S73454 probable GTP-binding protein yyaF - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1673787|gb|AAB95776.1| (AE000015) similar to GTPases [Mycoplasma pneumoniae] Length = 362 Score = 78.4 bits (190), Expect = 1e-13 Identities = 53/149 (35%), Positives = 79/149 (52%), Gaps = 30/149 (20%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130 +VGLPNVGKS L A+T + VE A+YPF T EP ++N D ++ Sbjct: 6 IVGLPNVGKSTLFSAITNLQVEIANYPFATIEPNAGIVNVIDERLDKLASLIKPDKVTHT 65 Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177 + V++ GL++GA+ G+G+G Q LA IR D I V+ E DP+ + Sbjct: 66 TFRFVDIAGLVKGASKGEGLGNQFLANIREVDLICHVVRCYEDKKIVHVNNQVDPVFDFE 125 Query: 178 ILLREFERAGIK-VNKRRPRIEIRRTPSG 205 I++ E +A I+ VN R +I+ R+ SG Sbjct: 126 IIVNELIQADIEVVNTRIGKIK-RKAESG 153 >pir||PC7024 hypothetical 218 protein - Acholeplasma laidlawii (fragment) Length = 218 Score = 78.4 bits (190), Expect = 1e-13 Identities = 50/144 (34%), Positives = 78/144 (53%), Gaps = 29/144 (20%) Query: 84 IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD---------------- 127 I +VGLPNVGKS L A+T V +A+YPF T +P +++ KD Sbjct: 4 IGIVGLPNVGKSTLFNAITKSQVTAANYPFATIDPNVGVVHVKDERLEKLAAIYKSGKII 63 Query: 128 -VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQ 175 I+ +++ GL++GA+ G+G+G Q L+ IR DAIA VI E DP++ Sbjct: 64 PTTIEFIDIAGLVKGASSGEGLGNQFLSHIRQVDAIAHVIRCFEDSEITHVEGKVDPLRD 123 Query: 176 MKILLREFERAGIK-VNKRRPRIE 198 ++I+ E + ++ V+KR R+E Sbjct: 124 LEIIEIELRLSDLESVDKRLARLE 147 >pir||E71920 hypothetical protein jhp0516 - Helicobacter pylori (strain J99) >gi|4155073|gb|AAD06109.1| (AE001485) putative [Helicobacter pylori J99] Length = 366 Score = 76.5 bits (185), Expect = 5e-13 Identities = 92/369 (24%), Positives = 158/369 (41%), Gaps = 87/369 (23%) Query: 86 LVGLPNVGKSELLRALTGV-DVESADYPFTTTEPIPAMMNYKDVQ--------------- 129 +VGLPNVGKS ALT + +SA+YPF T EP A++N D + Sbjct: 7 IVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILH 66 Query: 130 --IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQM 176 ++ V++ GLI+GA+ G+G+G Q LA I+ + I V+ E DP+ + Sbjct: 67 SVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKIDPLNDI 126 Query: 177 KILLREFERAGI-KVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAE 235 + + E A I ++KR R++ +++ K D +++ K H E Sbjct: 127 ETIELELILADIATLDKRIDRLQ-----------KALKSSK-DAKNLLECALSLKTHLEE 174 Query: 236 ITVRE--PVTLEDFADALDESLVW---KKAIIIANKGDAP-GSKDNYEKLVKAYG--ERF 287 + + P+ + LD+ L + KK I +AN G+ + + K V+ + + Sbjct: 175 LKPAKTFPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNILNEHAKKVENHAKVQNS 234 Query: 288 KIIPVSAKKRINL-----DAVKEALYDVA-----------------EIIRVFTKSPGEEP 325 + + + AK + D VKE L + +I FT E Sbjct: 235 EFVALCAKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVR 294 Query: 326 AYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPD 373 ++ +K+GS+ A IHKD K F A + + + G+ G D Sbjct: 295 SW---TIKKGSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKD 351 Query: 374 HVLEDGDIV 382 ++++DGD++ Sbjct: 352 YIVQDGDVL 360 >emb|CAC12034.1| (AL445065) GTP-binding protein Obg related protein [Thermoplasma acidophilum] Length = 382 Score = 76.5 bits (185), Expect = 5e-13 Identities = 43/121 (35%), Positives = 67/121 (54%), Gaps = 24/121 (19%) Query: 81 AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP---------------IPAMMNY 125 + +I LVG PNVGKS A T + E D+PFTT +P I A N Sbjct: 2 SVKIGLVGEPNVGKSTFFSAATQNEAEIGDFPFTTVKPNLGMTFFTVKCPDTEIGARCNP 61 Query: 126 KD---------VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQM 176 ++ V +Q+++VPGLIEGA+ G+GMG + + IR+ DAI +++D+S + ++ Sbjct: 62 REGYCENGIRHVPVQVIDVPGLIEGASEGRGMGNEFMDAIRDVDAIVLIVDVSSGSVDEI 121 Query: 177 K 177 + Sbjct: 122 R 122 >pir||E70477 GTP-binding protein obg - Aquifex aeolicus >gi|2984292|gb|AAC07816.1| (AE000771) GTP-binding protein [Aquifex aeolicus] Length = 343 Score = 75.7 bits (183), Expect = 8e-13 Identities = 59/195 (30%), Positives = 97/195 (49%), Gaps = 22/195 (11%) Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYK-DVQIQLVEVPGLIE 140 A + LVG PN GKS LL LT + ADYPFTT P +M + ++ + ++PGLIE Sbjct: 161 ADVGLVGFPNAGKSTLLSRLTRAKPKIADYPFTTLSPNLGVMELDWERRLVIADIPGLIE 220 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSE----DPIKQMKILLREFERAGIKVNKRRPR 196 A G G+G + L I +A VID+S+ +P++ + + RE E K+ ++P+ Sbjct: 221 DAHKGAGLGHEFLRHIERTKFLAHVIDVSDFREREPVQAFEAINRELELYSPKL-AQKPQ 279 Query: 197 IEIRRTPSGGIVINGIENI--KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDES 254 I +V N I+ + + ++E+ K +E+ ++ +E+ + L Sbjct: 280 I---------VVANKIDALSDRSLLSELEKYFKEKGYEFYAVSALTGEGIEELKEGL--- 327 Query: 255 LVWKKAIIIANKGDA 269 WKK I +K A Sbjct: 328 --WKKYEEIRDKESA 340 >pir||B82532 GTP-binding protein XF2641 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9107872|gb|AAF85438.1|AE004071_6 (AE004071) GTP-binding protein [Xylella fastidiosa] Length = 363 Score = 75.7 bits (183), Expect = 8e-13 Identities = 92/363 (25%), Positives = 150/363 (40%), Gaps = 78/363 (21%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ---------------- 129 +VGLPNVGKS L ALT + +A++PF T EP ++ D + Sbjct: 7 IVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGVVPVPDPRLNQLAEIVKPQKLLPT 66 Query: 130 -IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177 I+ V++ GL+ GAA G+G+G + LA IR DAIA V+ E DP+ ++ Sbjct: 67 VIEFVDIAGLVAGAASGEGLGNKFLAHIREVDAIAHVVRCFEHGQIIHVAGKVDPLADIE 126 Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEK-IHSAEI 236 I+ E A + ++ +R G +++ + + L E K SA + Sbjct: 127 IIDTELILADLDTVEKACNRMMRAAKGGDKEAIACKSV---LERLQVALNEGKSARSAGL 183 Query: 237 TVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDN--YEKL-VKAYGERFKIIPVS 293 E + D L K + IAN + G +DN E L V+A + +++P+S Sbjct: 184 DEDERALVRDLF-----LLTLKPVMYIANVLE-NGFQDNVYLEALRVRAASDNAQLVPIS 237 Query: 294 A----------------------KKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIA 331 A + L+ V A Y + + FT E A+ Sbjct: 238 AVIEEELAQLEDVDRDAFLVDLGLEEPGLNRVVRAAYALLGLQTYFTAGVKEVRAW---T 294 Query: 332 LKRGSTVLDVAERIHKDLVKNFRYAR--VWGKSVKFPGQR----------VGPDHVLEDG 379 +K G+T A IH D K F A + +K+ G+ G ++ +++G Sbjct: 295 VKSGATAPQAAAVIHTDFEKGFIRAETIAFDDFIKYKGEAGARDAGRMRLEGKEYRVQEG 354 Query: 380 DIV 382 D++ Sbjct: 355 DVL 357 >pir||H81425 probable GTP-binding protein Cj0096 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6967590|emb|CAB72580.1| (AL139074) putative GTP-binding protein [Campylobacter jejuni] Length = 350 Score = 74.9 bits (181), Expect = 1e-12 Identities = 52/164 (31%), Positives = 88/164 (52%), Gaps = 3/164 (1%) Query: 68 KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127 KG + ++ + A + LVG PNVGKS L+ ++ E A+Y FTT P +++ + Sbjct: 145 KGESRLVRLELKLIADVGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVNE 204 Query: 128 V-QIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVID-LSEDPIKQMKILLR-EFE 184 + ++PG+IEGA+ GKG+G L I + V+D + + P+K+ I+LR E E Sbjct: 205 YNSFVMADIPGIIEGASGGKGLGLAFLKHIERTSFLLFVLDPMRQMPLKEQFIVLRKELE 264 Query: 185 RAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLRE 228 + ++ R+ I I ++ S + E I +INE+ L+E Sbjct: 265 KFSNELFGRKFGIMISKSDSVRLGEEFAEQIALNINELDNYLKE 308 >sp|P37518|YYAF_BACSU HYPOTHETICAL 40.1 KD GTP-BINDING PROTEIN IN RPSF-SPO0J INTERGENIC REGION >gi|2127015|pir||S66016 probable GTP-binding protein yyaF - Bacillus subtilis >gi|467376|dbj|BAA05222.1| (D26185) unknown [Bacillus subtilis] >gi|2636639|emb|CAB16129.1| (Z99124) similar to hypothetical proteins [Bacillus subtilis] Length = 366 Score = 74.9 bits (181), Expect = 1e-12 Identities = 87/365 (23%), Positives = 143/365 (38%), Gaps = 79/365 (21%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQ-------------- 131 +VGLPNVGKS L A+T ESA+YPF T +P ++ D ++Q Sbjct: 7 IVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLQKLTELVNPKKTVPT 66 Query: 132 ---LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL-----------SEDPIKQMK 177 ++ G+++GA+ G+G+G + L+ IR DAI V+ DPI ++ Sbjct: 67 AFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICHVVRAFSDDNITHVSGKVDPIDDIE 126 Query: 178 ILLREFERAGIK-VNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEI 236 + E A ++ V KR R+ + E I + E + E+ S E Sbjct: 127 TINLELILADMETVEKRITRVSKLAKQKDKDAVFEFE-ILSKLKEAFE--SEKPARSVEF 183 Query: 237 TVREPVTLEDFADALDESLVWKKAIIIANKGD----APGSKDNYEKLVK-AYGERFKIIP 291 T + ++ L K + +AN + P +N K+ + A GE ++I Sbjct: 184 TEEQQKLVKQL-----HLLTSKPILYVANVSEDEVADPSGNENVAKIREYAAGENAEVIV 238 Query: 292 VSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPP 329 V AK + LD + +A Y + + FT E A+ Sbjct: 239 VCAKIESEIAELEGEEKQMFLEELGIQESGLDQLIKASYSLLGLATYFTAGEQEVRAW-- 296 Query: 330 IALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPG------------QRVGPDHVLE 377 K+G + A IH D + F A G + G ++V++ Sbjct: 297 -TFKKGMKAPECAGIIHSDFERGFIRAETVAYEDLLAGGGMAGAKEAGKVRLEGKEYVVQ 355 Query: 378 DGDIV 382 DGD++ Sbjct: 356 DGDVI 360 >sp|P44681|YCHF_HAEIN PROBABLE GTP-BINDING PROTEIN HI0393 >gi|1074386|pir||I64150 probable GTP-binding protein HI0393 - Haemophilus influenzae (strain Rd KW20) >gi|1573365|gb|AAC22052.1| (U32723) conserved hypothetical GTP-binding protein [Haemophilus influenzae Rd] Length = 363 Score = 74.5 bits (180), Expect = 2e-12 Identities = 89/365 (24%), Positives = 146/365 (39%), Gaps = 82/365 (22%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130 +VGLPNVGKS L ALT +E+A+YPF T EP ++ D ++ Sbjct: 7 IVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNTGVVPMPDPRLDALAEIVKPERILPT 66 Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177 + V++ GL+ GA+ G+G+G + LA IR DAI V+ E DP+ + Sbjct: 67 TMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENDDIVHVAGKIDPLDDID 126 Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKML----REEKIHS 233 + E A + +R + +R G + K +++ + K+L I S Sbjct: 127 TINTELALADLDSCERAIQRLQKRAKGGD------KEAKFELSVMEKILPVLENAGMIRS 180 Query: 234 AEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVK--AYGERFKIIP 291 + E ++ + L K + IAN + + Y V+ A E ++P Sbjct: 181 VGLDKEELQAIKSY-----NFLTLKPTMYIANVNEDGFENNPYLDRVREIAAKEGAVVVP 235 Query: 292 VSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPP 329 V A + L+ V A Y + + FT E A+ Sbjct: 236 VCAAIESEIAELDDEEKVEFLQDLGIEEPGLNRVIRAGYALLNLQTYFTAGVKEVRAW-- 293 Query: 330 IALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPDHVLE 377 + G+T A IH D K F A V + ++F G+ G D++++ Sbjct: 294 -TVSVGATAPKAAAVIHTDFEKGFIRAEVIAYEDFIQFNGENGAKEAGKWRLEGKDYIVQ 352 Query: 378 DGDIV 382 DGD++ Sbjct: 353 DGDVM 357 >pir||C70129 probable GTP-binding protein BB0235 - Lyme disease spirochete >gi|2688121|gb|AAC66614.1| (AE001133) conserved hypothetical protein [Borrelia burgdorferi] Length = 368 Score = 73.7 bits (178), Expect = 3e-12 Identities = 84/363 (23%), Positives = 147/363 (40%), Gaps = 73/363 (20%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130 +VGLPNVGKS L +LT +VE A+YPF T EP ++ D ++ Sbjct: 7 IVGLPNVGKSTLFSSLTSSNVEIANYPFCTIEPNIGIVEIPDERLLKISECIIPRKIIPA 66 Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED-----------PIKQMK 177 + V++ GL++GA+ G+G+G + LA IR I V+ E+ P K + Sbjct: 67 VMEFVDIAGLVKGASTGEGLGNKFLANIREVSLIVHVVRCFEEKEVIHINDDINPEKDIT 126 Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEIT 237 + E + ++ ++ + + + S + I ++ ML+ + H + + Sbjct: 127 TINVELCLSDLETVQKSLQKQEKNAKSTD------KKISESSKAIVLMLKRLEDHLSNMN 180 Query: 238 VREPVTLEDFADALDES---LVWKKAIIIANKGDAPGSKDNYEKLVK--AYGERFKIIPV 292 +DF S L +KK + + N + S + Y +VK A E + + Sbjct: 181 PAVEFKFDDFEYNFIRSLNLLTFKKVLYVCNVDENSLSGNKYTDIVKNIALKEGNDFLIL 240 Query: 293 SAKKRINLDAVKEALYDVAEIIRVFTKSPGE-----EPAYPPIAL--------------- 332 AK L +K+ Y E++++F + + AY + L Sbjct: 241 CAKIEAELAQIKDISYK-NEMLKLFGINDSGLGNLIKKAYYTLGLRTYFTAGLQEVRAWT 299 Query: 333 -KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRV------------GPDHVLEDG 379 K+G A IH D + F A V+ F Q V G ++++ DG Sbjct: 300 FKQGMRAPKAAGIIHSDFERGFIKAEVYSCEDLFKFQSVQKLKEKGLVRIEGKEYIVRDG 359 Query: 380 DIV 382 D++ Sbjct: 360 DVI 362 >pir||S48582 hypothetical protein - Mycoplasma capricolum (SGC3) (fragment) >gi|7451193|pir||S77880 probable GTP-binding protein MC010 - Mycoplasma capricolum (fragment) >gi|950066|emb|CAA83699.1| (Z33013) similar to GTP-bind. GTP1/OBG family [Mycoplasma capricolum] Length = 178 Score = 73.4 bits (177), Expect = 4e-12 Identities = 42/106 (39%), Positives = 58/106 (54%), Gaps = 17/106 (16%) Query: 83 QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ------------- 129 Q+ +VGLPNVGKS L A+T VE+A+YPF T EP ++ D + Sbjct: 4 QVGIVGLPNVGKSTLFNAITNSKVEAANYPFATIEPNVGIVEVPDYRLDELYKIFNSKKR 63 Query: 130 ----IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED 171 I+ V++ GLI GA+ G+G+G LA IR DAI V+ +D Sbjct: 64 VATTIEFVDIAGLIAGASQGEGLGNAFLANIRQTDAICQVVRCFDD 109 >pir||T42036 obg protein - Streptomyces coelicolor >gi|1783290|dbj|BAA13498.1| (D87915) Obg [Streptomyces coelicolor A3(2)] >gi|6983737|emb|CAB75376.1| (AL139298) GTP-binding protein [Streptomyces coelicolor A3(2)] Length = 478 Score = 72.6 bits (175), Expect = 7e-12 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 18/186 (9%) Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141 A + LVG P+ GKS L+ L+ + ADYPFTT P ++ + + +VPGLI G Sbjct: 160 ADVALVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGETVYTVADVPGLIPG 219 Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLS-----EDPIKQMKILLREFERAGIKVNKRRPR 196 A+ GKG+G + L + + V+D + DP+ + ++ E G N RPR Sbjct: 220 ASQGKGLGLEFLRHVERCSVLVHVLDTATLESERDPLSDLDVIETELREYGGLDN--RPR 277 Query: 197 IEIRRTPSGGIVINGIENIKG-DINEVMKMLREEKIHSA-EITVREPVTLEDFADALDES 254 I +V+N I+ G D+ E+++ E + + E++ + L + + AL E Sbjct: 278 I---------VVLNKIDVPDGKDLAEMVRPDLEARGYRVFEVSAVAHMGLRELSFALAEL 328 Query: 255 LVWKKA 260 + +A Sbjct: 329 VATARA 334 >pir||S74797 GTP-binding protein obg - Synechocystis sp. (strain PCC 6803) >gi|1652022|dbj|BAA16948.1| (D90901) GTP-binding protein [Synechocystis sp.] Length = 368 Score = 72.2 bits (174), Expect = 9e-12 Identities = 45/140 (32%), Positives = 76/140 (54%), Gaps = 12/140 (8%) Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP-IPAMMNYKDVQIQLVEVPGLIE 140 A++ ++GLPN GKS L+ AL+ + ADYPFTT P + + ++PGLIE Sbjct: 160 AEVGIIGLPNAGKSTLIAALSAARPKIADYPFTTLVPNLGVVRKPTGDGTVFADIPGLIE 219 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSE-DPIKQMKILLREFERAGIKVNKRRPRIEI 199 GAA G G+G + L I + V+D++ DPI +++ +E + G + + +P+I Sbjct: 220 GAAAGIGLGHEFLRHIERTRLLLHVLDVTAGDPIANFRVIQQELDAYGRGITE-KPQI-- 276 Query: 200 RRTPSGGIVINGIENIKGDI 219 I +N I+ + G++ Sbjct: 277 -------IALNKIDALDGEM 289 >pir||T23645 hypothetical protein M01E5.2 - Caenorhabditis elegans >gi|3878629|emb|CAB07637.1| (Z93385) predicted using Genefinder~Similarity to B.subtilis GTP-binding protein (SW:P20964), contains similarity to Pfam domain: PF01018 (GTP1/OBG family), Score=169.5, E-value=1e-49, N=1~cDNA EST yk457c2.5 comes from this gene [Caenorhabditis elegans] Length = 358 Score = 72.2 bits (174), Expect = 9e-12 Identities = 40/105 (38%), Positives = 61/105 (58%), Gaps = 5/105 (4%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDV-QIQLVEVPGLIEGAAL 144 LVG PN GKS LLRA++ + A YPFTT P ++ Y+D QI + ++PGLIE + L Sbjct: 193 LVGFPNAGKSSLLRAISRAKPKVASYPFTTLHPHIGVVFYEDFEQIAVADIPGLIEDSHL 252 Query: 145 GKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKILLREFER 185 KG+G L I +++ V+D S D K +++ L +++ Sbjct: 253 NKGLGISFLKHIERCESLWYVLDYSTGSLTDQYKMLRVELEGYQK 297 >pir||A81367 probable GTP-binding protein Cj0930 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968367|emb|CAB73187.1| (AL139076) putative GTP-binding protein [Campylobacter jejuni] Length = 367 Score = 72.2 bits (174), Expect = 9e-12 Identities = 85/364 (23%), Positives = 151/364 (41%), Gaps = 76/364 (20%) Query: 86 LVGLPNVGKSELLRALTGV-DVESADYPFTTTEPIPAMMNYKDVQ--------------- 129 +VGLPNVGKS ALT + +SA+YPF T EP AM+ D++ Sbjct: 7 IVGLPNVGKSTTFNALTKAQNAQSANYPFCTIEPNKAMVEVPDLRLNELAKIVKPERIMH 66 Query: 130 --IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQM 176 I+ V++ GL++GA+ G+G+G + L+ IR + I ++ + DP++ + Sbjct: 67 SLIEFVDIAGLVKGASKGEGLGNKFLSNIRETEVILHIVRCFDEENITHVEGGVDPLRDV 126 Query: 177 KILLREFERAGI-KVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAE 235 +I+ E A I +++K+ ++ + +E ++ + K L E Sbjct: 127 EIINTELILADIEQLSKKIEKLTKEAKANQKGAKESLELANSLLDHLNKGLAASSYPEKE 186 Query: 236 ITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDN-YEKLVKAYGER--FKIIPV 292 + + + E L K+ I AN + S+DN Y K +K Y ++ ++I + Sbjct: 187 SEIYQALIKE------LRLLSAKEVIYGANVDENGISEDNDYVKALKEYAKKNDHEVIKL 240 Query: 293 SAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPI 330 AK LD + + +I FT E ++ Sbjct: 241 CAKIEEELVGLSDEESHEFLSSLGVNESGLDQIIRTAFAKLGLISYFTAGVVEVRSW--- 297 Query: 331 ALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPDHVLED 378 +K+G A IH D K F A V + +++ G+ G D+++ D Sbjct: 298 TIKKGWKAPKAASVIHNDFEKGFIKAEVISYEDYIQYKGENGAKEAGKLRLEGKDYIVLD 357 Query: 379 GDIV 382 GD++ Sbjct: 358 GDVM 361 >gb|AAF75096.1|AC007583_32 (AC007583) It is a member of GTP1/OBG family PF|01018. [Arabidopsis thaliana] Length = 1029 Score = 72.2 bits (174), Expect = 9e-12 Identities = 41/119 (34%), Positives = 62/119 (51%), Gaps = 8/119 (6%) Query: 74 LAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLV 133 L ++ + A + LVG+PN GKS LL AL+ Y FTT P +NY D + + Sbjct: 832 LILELKSIADVGLVGMPNAGKSTLLGALSRAKPRVGHYAFTTLRPNLGNVNYDDFSMTVA 891 Query: 134 EVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE--------DPIKQMKILLREFE 184 ++PGLI+GA +G+G L I +A V+DL+ P +Q++ L+ E E Sbjct: 892 DIPGLIKGAHQNRGLGHNFLRHIERTKVLAYVVDLASGLDGCEGLTPWQQLRDLVMELE 950 >gb|AAF79543.1|AC022464_1 (AC022464) F22G5.1 [Arabidopsis thaliana] Length = 445 Score = 72.2 bits (174), Expect = 9e-12 Identities = 41/119 (34%), Positives = 62/119 (51%), Gaps = 8/119 (6%) Query: 74 LAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLV 133 L ++ + A + LVG+PN GKS LL AL+ Y FTT P +NY D + + Sbjct: 248 LILELKSIADVGLVGMPNAGKSTLLGALSRAKPRVGHYAFTTLRPNLGNVNYDDFSMTVA 307 Query: 134 EVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE--------DPIKQMKILLREFE 184 ++PGLI+GA +G+G L I +A V+DL+ P +Q++ L+ E E Sbjct: 308 DIPGLIKGAHQNRGLGHNFLRHIERTKVLAYVVDLASGLDGCEGLTPWQQLRDLVMELE 366 >dbj|BAA13501.1| (D87916) Obg [Streptomyces griseus] Length = 478 Score = 71.8 bits (173), Expect = 1e-11 Identities = 42/134 (31%), Positives = 66/134 (48%), Gaps = 7/134 (5%) Query: 69 GGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDV 128 G + ++ + A + LVG P+ GKS L+ L+ + ADYPFTT P ++ Sbjct: 147 GESRDIVLELKTVADVALVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGST 206 Query: 129 QIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS-----EDPIKQMKILLREF 183 + +VPGLI GA+ GKG+G + L + + V+D + DP+ + ++ E Sbjct: 207 VYTIADVPGLIPGASQGKGLGLEFLRHVERCSVLVHVLDTATLESDRDPVSDLDMIEEEL 266 Query: 184 ERAGIKVNKRRPRI 197 G N RPRI Sbjct: 267 RLYGGLEN--RPRI 278 >pir||D81037 GTP-binding protein, probable NMB1838 [imported] - Neisseria meningitidis (group B strain MD58, group A strain Z2491) >gi|7227093|gb|AAF42173.1| (AE002533) GTP-binding protein, putative [Neisseria meningitidis MC58] >gi|7379353|emb|CAB83908.1| (AL162753) hypothetical protein NMA0618 [Neisseria meningitidis Z2491] Length = 363 Score = 71.8 bits (173), Expect = 1e-11 Identities = 40/103 (38%), Positives = 57/103 (54%), Gaps = 17/103 (16%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ---------------- 129 +VGLPNVGKS L ALT +E+A+YPF T EP ++ D + Sbjct: 7 IVGLPNVGKSTLFNALTQSGIEAANYPFCTIEPNVGIVEVPDPRMAELAKIVNPQKMQPA 66 Query: 130 -IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED 171 ++ V++ GL+ GA+ G+G+G Q LA IR DAI V+ +D Sbjct: 67 IVEFVDIAGLVAGASKGEGLGNQFLANIRETDAIVNVVRCFDD 109 >pir||F71665 hypothetical protein RP604 - Rickettsia prowazekii >gi|3861148|emb|CAA15048.1| (AJ235272) unknown [Rickettsia prowazekii] Length = 365 Score = 71.4 bits (172), Expect = 2e-11 Identities = 85/359 (23%), Positives = 150/359 (41%), Gaps = 68/359 (18%) Query: 86 LVGLPNVGKSELLRALTGVDV-ESADYPFTTTEPIPAMMNYKDVQIQ------------- 131 +VGLPNVGKS L ALT + ++A+YPF T EP + + D ++Q Sbjct: 7 IVGLPNVGKSTLFNALTASQIADAANYPFCTIEPNSSKVLVPDERLQRLVSLVGSNKMIP 66 Query: 132 ----LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED-----------PIKQM 176 V++ GL++GA+ G G+G + L+ IR DAI V+ ED P+ + Sbjct: 67 SYIEFVDIAGLVKGASKGDGLGNKFLSHIREVDAILHVLRCFEDEDIMHVHNKIDPLYDI 126 Query: 177 KILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEK------ 230 +++ E I ++ +R SG + +E I + E+ K+L E K Sbjct: 127 EVIETELILTDIASLEKHFIKSEKRLKSGDKKM--VEQI-ALLKEIYKVLAEGKPARILN 183 Query: 231 -------IHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSK--------DN 275 + ++ +P+ D ++ K ++A + + +K ++ Sbjct: 184 EVLGADNLKQLQLITSKPILYVCNVFEQDAAIGNKFTQLVAKRAETEKTKSLVISSKIES 243 Query: 276 YEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRG 335 L+++ E+ + + + L V + Y++ + FT P E ++ K G Sbjct: 244 EIALLESVEEKEEFLKYIGLNKTGLSKVIKEGYNLLNLKSFFTIGPKEAHSW---TFKDG 300 Query: 336 STVLDVAERIHKDLVKNFRYARVWG-----------KSVKFPGQRV-GPDHVLEDGDIV 382 + A IH D K F A V K+ + R+ G D+ ++DGDIV Sbjct: 301 TLAPAAAGIIHTDFEKGFIRAEVISYEDYINLGSEAKAKEVGKMRLEGKDYKMQDGDIV 359 >dbj|BAA91783.1| (AK001603) unnamed protein product [Homo sapiens] Length = 401 Score = 71.0 bits (171), Expect = 2e-11 Identities = 41/113 (36%), Positives = 64/113 (56%), Gaps = 2/113 (1%) Query: 74 LAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYK-DVQIQL 132 L ++ + A +VG PN GKS LLRA++ A YPFTT +P +++Y+ +QI + Sbjct: 217 LHLELKTVAHAGMVGFPNAGKSSLLRAISNARPAVASYPFTTLKPHVGIVHYEGHLQIAV 276 Query: 133 VEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-DPIKQMKILLREFE 184 ++PG+I GA +G+G L I + V+DLS+ +P Q+ L E E Sbjct: 277 ADIPGIIRGAHQNRGLGSAFLRHIERCRFLLFVVDLSQPEPWTQVDDLKYELE 329 >dbj|BAB13092.1| (AP001119) hypothetical 43.3 kD GTP-binding protein in dacB-rpmA intergenic region (F390) [Buchnera sp. APS] Length = 334 Score = 71.0 bits (171), Expect = 2e-11 Identities = 39/119 (32%), Positives = 68/119 (56%), Gaps = 6/119 (5%) Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMN-YKDVQIQLVEVPGLIE 140 A + +G+PNVGKS L+ ++G + +DYPFTT P+ +N K+ + + ++PG+I+ Sbjct: 160 ADVGTLGMPNVGKSTLVTNISGAKTKISDYPFTTLHPVLGSVNIQKNKKFIIADIPGIIK 219 Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSED----PIKQMKILLREFERAGIKV-NKRR 194 GA+ G G+G + L + + +IDL P +K +L E ++ +K+ NK R Sbjct: 220 GASYGAGLGIRFLKHLERCKLLLHIIDLVPQNNCHPSDNIKTVLNELKKYSLKLYNKPR 278 >sp|P42641|YHBZ_ECOLI HYPOTHETICAL 43.3 KD GTP-BINDING PROTEIN IN DACB-RPMA INTERGENIC REGION >gi|7428736|pir||A65109 GTP-binding protein obg - Escherichia coli (strain K-12) >gi|606121|gb|AAA57984.1| (U18997) ORF_f390 [Escherichia coli] >gi|1789574|gb|AAC76215.1| (AE000399) putative GTP-binding factor [Escherichia coli K12] Length = 390 Score = 70.6 bits (170), Expect = 3e-11 Identities = 39/111 (35%), Positives = 63/111 (56%), Gaps = 9/111 (8%) Query: 82 AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP---IPAMMNYKDVQIQLVEVPGL 138 A + ++G+PN GKS +RA++ + ADYPFTT P + M N K + ++PGL Sbjct: 160 ADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVV--ADIPGL 217 Query: 139 IEGAALGKGMGPQLLAVIRNADAIAIVIDL----SEDPIKQMKILLREFER 185 IEGAA G G+G + L + + +ID+ DP++ +I++ E E+ Sbjct: 218 IEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEK 268 >pir||H83074 GTP-binding protein Obg PA4566 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950812|gb|AAG07954.1|AE004870_5 (AE004870) GTP-binding protein Obg [Pseudomonas aeruginosa] Length = 406 Score = 70.6 bits (170), Expect = 3e-11 Identities = 42/134 (31%), Positives = 72/134 (53%), Gaps = 9/134 (6%) Query: 67 RKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP---IPAMM 123 + G L ++ + A + L+GLPN GKS +RA++ + ADYPFTT P + ++ Sbjct: 145 KPGEARDLKLELKVLADVGLLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPNLGVVSVG 204 Query: 124 NYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKIL 179 YK + ++PGLIEGAA G G+G + L + + ++D++ DP +++ Sbjct: 205 RYKSFVV--ADIPGLIEGAAEGAGLGIRFLKHLARTRILLHLVDMAPLDESDPADAAEVI 262 Query: 180 LREFERAGIKVNKR 193 +RE R + +R Sbjct: 263 VRELGRFSPALTER 276 >pir||T30310 probable GTP binding protein - Lactococcus lactis (fragment) >gi|2909718|gb|AAC12968.1| (U76424) putative GTP binding protein [Lactococcus lactis] Length = 214 Score = 70.2 bits (169), Expect = 4e-11 Identities = 49/151 (32%), Positives = 75/151 (49%), Gaps = 34/151 (22%) Query: 86 LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130 +VGLPNVGKS L A+T E+A+YPF T +P M+ D ++ Sbjct: 7 IVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLNKLTELIKPKKTVPT 66 Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVI---------------DLSEDPI 173 + ++ G+++GA+ G+G+G + LA IR DAI V+ D DP+ Sbjct: 67 TFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIIHVVRAFDDENVMRENNREDAFIDPM 126 Query: 174 KQMKILLREFERAGIK-VNKRRPRIE-IRRT 202 ++ + E A ++ VNKR R+E I RT Sbjct: 127 ADIETINLELILADLESVNKRYARVEKIART 157 >pir||S75088 probable GTP-binding protein sll0245 - Synechocystis sp. (strain PCC 6803) >gi|1653033|dbj|BAA17950.1| (D90910) hypothetical protein [Synechocystis sp.] Length = 363 Score = 69.9 bits (168), Expect = 5e-11 Identities = 90/359 (25%), Positives = 149/359 (41%), Gaps = 69/359 (19%) Query: 86 LVGLPNVGKSELLRALTG-VDVESADYPFTTTEPIPAMMNYKD----------------- 127 +VGLPNVGKS L AL E+A++PF T EP +++ D Sbjct: 6 IVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVSVPDDRLGKLAEISQSVKVVP 65 Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL-----------SEDPIKQM 176 +++ V++ GL+ GA+ G+G+G Q LA IR DAI V+ S DP++ + Sbjct: 66 TRMEFVDIAGLVAGASKGEGLGNQFLANIREVDAIVHVVRCFDDDDIIHVSGSVDPVRDV 125 Query: 177 KILLREFERAGI-KVNKR--RPRIEIRRTPSGGIVINGIENIKGDINEVMKMLR------ 227 +++ E A + +V KR R R + R + +E + +NE + R Sbjct: 126 EVIDLELVLADLAQVEKRLERSRKQARGNKDLLEEVAILERLVAALNEGIPARRVGLTAE 185 Query: 228 -EEKIHSAEITVREP------VTLEDFADALDESLVWKKAI-IIANKGDAP----GSKDN 275 +E I S + +P VT +D A D W + + IA K +A ++ Sbjct: 186 EQELIKSLGLLTLKPIIYATNVTEDDLAGGND----WVEQVKAIAAKDEAKVVVISAQVE 241 Query: 276 YEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRG 335 E + ER + L ++ A Y++ + T P E A+ I+ G Sbjct: 242 SELVELPEEERQDFLASLGVTEGGLKSLIRATYELLGLRTYLTTGPQETRAWTIIS---G 298 Query: 336 STVLDVAERIHKDLVKNFRYAR------------VWGKSVKFPGQRVGPDHVLEDGDIV 382 A IH D + F A + G K + G ++V+++GD++ Sbjct: 299 MKAPQAAGVIHTDFERGFIRAETVAYEDLISCGSMQGAKEKGLVRSEGKEYVVQEGDVL 357 >sp|P75215|Y384_MYCPN PROBABLE GTP-BINDING PROTEIN MG384 HOMOLOG >gi|2146144|pir||S73605 GTP-binding protein obg - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1673950|gb|AAB95927.1| (AE000027) small GTPase OBG involved in cell growth [Mycoplasma pneumoniae] Length = 433 Score = 69.9 bits (168), Expect = 5e-11 Identities = 38/139 (27%), Positives = 72/139 (51%), Gaps = 4/139 (2%) Query: 68 KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127 KG ++++ + A + +VG PN GKS L+ L+ + A+Y FTT P+ ++ + D Sbjct: 146 KGQSLHVSLEIKYLANVGIVGFPNTGKSTLISKLSNAKPKIANYRFTTLVPVLGVVKHND 205 Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKILLREF 183 + ++PGLIE A+ G G+G L I + + +I L +DP + + ++RE Sbjct: 206 QSLVFADIPGLIENASEGSGLGHYFLRHIERCEILIHLISLDPVDHDDPCQAYEQIMREL 265 Query: 184 ERAGIKVNKRRPRIEIRRT 202 + + K++ + +T Sbjct: 266 SKYSQLLVKKKMLVVANKT 284 >pir||F70680 probable obg - Mycobacterium tuberculosis (strain H37RV) >gi|1666144|emb|CAB03779.1| (Z81451) obg [Mycobacterium tuberculosis] Length = 479 Score = 69.1 bits (166), Expect = 8e-11 Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 5/120 (4%) Query: 68 KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127 KG L ++ + A + LVG P+ GKS L+ A++ + ADYPFTT P +++ + Sbjct: 146 KGQSRDLTLELKTVADVGLVGFPSAGKSSLVSAISAAKPKIADYPFTTLVPNLGVVSAGE 205 Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS-----EDPIKQMKILLRE 182 + +VPGLI GA+ G+G+G L I + V+D + DPI + L E Sbjct: 206 HAFTVADVPGLIPGASRGRGLGLDFLRHIERCAVLVHVVDCATAEPGRDPISDIDALETE 265 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.316 0.137 0.378 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 139656698 Number of Sequences: 2977 Number of extensions: 5816384 Number of successful extensions: 22383 Number of sequences better than 1.0e-10: 85 Number of HSP's better than 0.0 without gapping: 43 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 22113 Number of HSP's gapped (non-prelim): 102 length of query: 387 length of database: 189,106,746 effective HSP length: 59 effective length of query: 328 effective length of database: 153,796,013 effective search space: 50445092264 effective search space used: 50445092264 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 166 (69.1 bits)