BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB2026 (PAB2026) DE:GTP-BINDING PROTEIN
         (387 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75167 GTP-binding protein PAB2026 - Pyrococcus abyssi (str...   761  0.0
pir||H71047 probable developmentally regulated GTP-binding prote...   729  0.0
pir||F72509 probable developmentally regulated GTP-binding prote...   309  3e-83
gi|11499729 GTP-binding protein [Archaeoglobus fulgidus] >gi|742...   286  4e-76
pir||E64465 GTP-binding protein DRG homolog - Methanococcus jann...   264  1e-69
pir||F69083 GTP-binding protein DRG homolog - Methanobacterium t...   249  5e-65
gb|AAK42533.1| GTP binding conserved hypothetical protein [Sulfo...   244  1e-63
gb|AAF21162.1|AC010926_14 (AC010926) putative GTP-binding protei...   233  3e-60
gb|AAF55688.1| (AE003727) CG6195 gene product [Drosophila melano...   232  6e-60
gb|AAF97313.1|AC007843_16 (AC007843) GTP binding protein [Arabid...   230  2e-59
sp|P43690|DRG1_XENLA DEVELOPMENTALLY REGULATED GTP-BINDING PROTE...   229  5e-59
pir||T39192 probable GTP-binding protein - fission yeast  (Schiz...   228  7e-59
pir||T42381 probable GTP-binding protein - fission yeast  (Schiz...   228  1e-58
gi|4758796 developmentally regulated GTP-binding protein 1; neur...   228  1e-58
gi|11417999 developmentally regulated GTP-binding protein 1 [Hom...   228  1e-58
gi|6681225 developmentally regulated GTP-binding protein 1 [Mus ...   228  1e-58
gb|AAB53256.1| (U66408) GTP-binding protein [Arabidopsis thalian...   227  2e-58
pir||JC1349 GTP-binding protein DRG [validated] - mouse               226  3e-58
emb|CAC12607.1| (AL445067) GTP-binding protein [Thermoplasma aci...   225  6e-58
gb|AAF79465.1|AC022492_9 (AC022492) F1L3.17 [Arabidopsis thaliana]    224  1e-57
pir||T09368 GTP-binding protein F23K16.150 - Arabidopsis thalian...   224  2e-57
gb|AAF58591.1| (AE003823) 128up gene product [Drosophila melanog...   224  2e-57
pir||T43254 GTP-binding protein - Thermoplasma acidophilum >gi|1...   223  2e-57
gi|10946678 developmentally regulated GTP-binding protein 2 [Mus...   221  9e-57
gi|4557537 developmentally regulated GTP-binding protein 2 [Homo...   221  1e-56
sp|P32234|128U_DROME GTP-BINDING PROTEIN 128UP >gi|422452|pir||S...   220  2e-56
gi|6319281 similar to Xenopus GTP-binding protein DRG; Fun11p [S...   220  2e-56
gb|AAC33135.1| (AF035177) GTP-binding protein [Oncorhynchus tsha...   220  2e-56
pir||T31553 hypothetical protein T28D6.6 - Caenorhabditis elegan...   220  2e-56
sp|P17103|YRB1_HALCU HYPOTHETICAL 40 KD GTP-BINDING PROTEIN IN R...   216  4e-55
gi|6321612 Ygr173wp [Saccharomyces cerevisiae] >gi|1723727|sp|P5...   214  1e-54
sp|P34280|YKK3_CAEEL HYPOTHETICAL 64.3 KD GTP-BINDING PROTEIN C0...   213  2e-54
gb|AAF77220.1|AC009601_14 (AC009601) L165.8 [Leishmania major]        204  2e-51
sp|P32235|GTP1_SCHPO GTP-BINDING PROTEIN 1 >gi|419815|pir||JT074...   202  5e-51
gi|11427872 developmentally regulated GTP-binding protein 2 [Hom...   198  1e-49
pir||T06251 GTP binding protein - garden pea >gi|2345148|gb|AAB6...   194  1e-48
emb|CAA19048.2| (AL023587) gtp-binding protein 1. [Schizosacchar...   190  2e-47
pir||T40599 hypothetical protein SPBC649.06 - fission yeast  (Sc...   190  2e-47
gb|AAG01361.1|AC068666_8 (AC068666) L165.8 [Leishmania major]         110  2e-23
emb|CAA74319.1| (Y13986) GTP-binding protein [Ostertagia circumc...   104  2e-21
pir||G72586 hypothetical protein APE1164 - Aeropyrum pernix (str...    99  8e-20
pir||T42690 hypothetical protein DKFZp434N1827.1 - human (fragme...    99  1e-19
pir||C64466 GTP-binding protein - Methanococcus jannaschii >gi|1...    96  5e-19
pir||C75402 conserved hypothetical protein - Deinococcus radiodu...    89  1e-16
pir||H71165 probable GTP-binding protein - Pyrococcus horikoshii...    88  2e-16
pir||H75066 GTP-binding protein PAB1357 - Pyrococcus abyssi (str...    87  3e-16
pir||E70354 probable GTP-binding protein - Aquifex aeolicus >gi|...    87  3e-16
gb|AAF97355.1| (AY005820) Obg-like protein [Thermococcus zilligii]     85  2e-15
dbj|BAB07770.1| (AP001520) GTP-binding protein [Bacillus halodur...    84  2e-15
sp|P47270|Y024_MYCGE PROBABLE GTP-BINDING PROTEIN MG024 >gi|1361...    83  5e-15
pir||B72418 conserved hypothetical protein - Thermotoga maritima...    83  6e-15
pir||G82870 GTP-binding protein UU595 [imported] - Ureaplasma ur...    82  8e-15
pir||D70197 GTP-binding protein obg - Lyme disease spirochete >g...    80  6e-14
pir||T40281 gtp-binding protein 1 - fission yeast (Schizosacchar...    80  6e-14
pir||A64591 probable GTP-binding protein gtp1 - Helicobacter pyl...    79  7e-14
pir||A72280 conserved hypothetical protein - Thermotoga maritima...    79  7e-14
pir||B75563 GTP-binding protein Obg - Deinococcus radiodurans (s...    79  1e-13
sp|P75088|Y024_MYCPN PROBABLE GTP-BINDING PROTEIN MG024 HOMOLOG ...    78  1e-13
pir||PC7024 hypothetical 218 protein - Acholeplasma laidlawii (f...    78  1e-13
pir||E71920 hypothetical protein jhp0516 - Helicobacter pylori (...    76  5e-13
emb|CAC12034.1| (AL445065) GTP-binding protein Obg related prote...    76  5e-13
pir||E70477 GTP-binding protein obg - Aquifex aeolicus >gi|29842...    76  8e-13
pir||B82532 GTP-binding protein XF2641 [imported] - Xylella fast...    76  8e-13
pir||H81425 probable GTP-binding protein Cj0096 [imported] - Cam...    75  1e-12
sp|P37518|YYAF_BACSU HYPOTHETICAL 40.1 KD GTP-BINDING PROTEIN IN...    75  1e-12
sp|P44681|YCHF_HAEIN PROBABLE GTP-BINDING PROTEIN HI0393 >gi|107...    75  2e-12
pir||C70129 probable GTP-binding protein BB0235 - Lyme disease s...    74  3e-12
pir||S48582 hypothetical protein - Mycoplasma capricolum (SGC3) ...    73  4e-12
pir||T42036 obg protein - Streptomyces coelicolor >gi|1783290|db...    73  7e-12
pir||S74797 GTP-binding protein obg - Synechocystis sp. (strain ...    72  9e-12
pir||T23645 hypothetical protein M01E5.2 - Caenorhabditis elegan...    72  9e-12
pir||A81367 probable GTP-binding protein Cj0930 [imported] - Cam...    72  9e-12
gb|AAF75096.1|AC007583_32 (AC007583) It is a member of GTP1/OBG ...    72  9e-12
gb|AAF79543.1|AC022464_1 (AC022464) F22G5.1 [Arabidopsis thaliana]     72  9e-12
dbj|BAA13501.1| (D87916) Obg [Streptomyces griseus]                    72  1e-11
pir||D81037 GTP-binding protein, probable NMB1838 [imported] - N...    72  1e-11
pir||F71665 hypothetical protein RP604 - Rickettsia prowazekii >...    71  2e-11
dbj|BAA91783.1| (AK001603) unnamed protein product [Homo sapiens]      71  2e-11
dbj|BAB13092.1| (AP001119) hypothetical 43.3 kD GTP-binding prot...    71  2e-11
sp|P42641|YHBZ_ECOLI HYPOTHETICAL 43.3 KD GTP-BINDING PROTEIN IN...    71  3e-11
pir||H83074 GTP-binding protein Obg PA4566 [imported] - Pseudomo...    71  3e-11
pir||T30310 probable GTP binding protein - Lactococcus lactis (f...    70  4e-11
pir||S75088 probable GTP-binding protein sll0245 - Synechocystis...    70  5e-11
sp|P75215|Y384_MYCPN PROBABLE GTP-BINDING PROTEIN MG384 HOMOLOG ...    70  5e-11
pir||F70680 probable obg - Mycobacterium tuberculosis (strain H3...    69  8e-11

>pir||F75167 GTP-binding protein PAB2026 - Pyrococcus abyssi (strain Orsay)
           >gi|5457931|emb|CAB49421.1| (AJ248284) GTP-BINDING
           PROTEIN [Pyrococcus abyssi]
           Length = 387
           
 Score =  761 bits (1944), Expect = 0.0
 Identities = 387/387 (100%), Positives = 387/387 (100%)

Query: 1   MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60
           MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL
Sbjct: 1   MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60

Query: 61  EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120
           EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP
Sbjct: 61  EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120

Query: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180
           AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL
Sbjct: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180

Query: 181 REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE 240
           REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE
Sbjct: 181 REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE 240

Query: 241 PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL 300
           PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL
Sbjct: 241 PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL 300

Query: 301 DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG 360
           DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG
Sbjct: 301 DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG 360

Query: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAR 387
           KSVKFPGQRVGPDHVLEDGDIVEIHAR
Sbjct: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAR 387


>pir||H71047 probable developmentally regulated GTP-binding protein - Pyrococcus
           horikoshii >gi|3258101|dbj|BAA30784.1| (AP000006) 387aa
           long hypothetical developmentally regulated GTP-binding
           protein [Pyrococcus horikoshii]
           Length = 387
           
 Score =  729 bits (1861), Expect = 0.0
 Identities = 360/387 (93%), Positives = 383/387 (98%)

Query: 1   MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60
           MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKR+LAELR+EL
Sbjct: 1   MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRRLAELRREL 60

Query: 61  EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120
           EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP+P
Sbjct: 61  EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPVP 120

Query: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180
           AMMNYKDVQIQLVEVPGL+EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQM+ILL
Sbjct: 121 AMMNYKDVQIQLVEVPGLLEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMEILL 180

Query: 181 REFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVRE 240
           REFERAGIKVNKRRPR+EIR+TPSGGIVING ENIKGD++EVM+MLREEKIHSAEITV+E
Sbjct: 181 REFERAGIKVNKRRPRVEIRKTPSGGIVINGAENIKGDLSEVMRMLREEKIHSAEITVKE 240

Query: 241 PVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINL 300
           PVTLE+FADALD+SLVWKKAIIIANKGD+PGSK+NY KL+  YGE+FKI+PVSAKKRINL
Sbjct: 241 PVTLEEFADALDDSLVWKKAIIIANKGDSPGSKENYHKLINKYGEKFKIVPVSAKKRINL 300

Query: 301 DAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWG 360
           +AVKEA+YDVAEIIRVFTKSPGEEPAYPPIALKRG+TV+DVAERIHKDLVKNFRYARVWG
Sbjct: 301 EAVKEAIYDVAEIIRVFTKSPGEEPAYPPIALKRGATVMDVAERIHKDLVKNFRYARVWG 360

Query: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAR 387
           KSVKFPGQRVGPDHVLEDGDIVEIHA+
Sbjct: 361 KSVKFPGQRVGPDHVLEDGDIVEIHAK 387


>pir||F72509 probable developmentally regulated GTP-binding protein APE2052 -
           Aeropyrum pernix (strain K1) >gi|5105750|dbj|BAA81062.1|
           (AP000063) 368aa long hypothetical developmentally
           regulated GTP-binding protein [Aeropyrum pernix]
           Length = 368
           
 Score =  309 bits (784), Expect = 3e-83
 Identities = 171/369 (46%), Positives = 242/369 (65%), Gaps = 8/369 (2%)

Query: 24  EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83
           EKI+ALE+  + VPKHKGTE L L  +R+LAELR+ELE++R++R GGG S  V+K GA Q
Sbjct: 3   EKIQALEEFISAVPKHKGTENLLLWARRRLAELREELEEKRKRRVGGGPSFFVEKSGAGQ 62

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
            VL+G PN GKS +L ALT    E ADYPFTT  P   M+ Y+D+Q Q+V+ P L+ G+ 
Sbjct: 63  AVLIGPPNSGKSSILAALTNAKPEVADYPFTTRMPRAGMLPYEDIQFQIVDTPPLLPGS- 121

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDP--IKQMKILLREFERAGIKVNKRRPRIEIRR 201
            G  +  ++L + RNADAI +V  L +DP  ++ +  ++RE E  GI + +RR    I +
Sbjct: 122 -GSSVNNRVLGLARNADAIILVFSL-DDPNLVETIDAVVREVEDRGIVITRRRGLARIMK 179

Query: 202 TPS-GGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259
           +    G+ I G   +     ++V ++L + +I++A + +   V+L+D   A+  +LV K 
Sbjct: 180 SREVTGVRIEGPGRLTDATEDDVRRLLSQYRIYNAIVYIEGDVSLDDVESAVYINLVRKP 239

Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGE-RFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318
           A+ I NK D PG+++  E  VK  GE     I  SA +   L  +   L+ + +I+RV+T
Sbjct: 240 ALAILNKADLPGAREAAEPAVKRLGEIGIDTIVASALRGDGLGEIAPRLFRMLDIVRVYT 299

Query: 319 KSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378
           K P +EP   P+ L RGSTV+DVA+ IHKDLV+ F+YARVWGKSVK+PGQRVGP+HV+ED
Sbjct: 300 KQPNKEPDKDPLVLHRGSTVMDVAKHIHKDLVRRFKYARVWGKSVKYPGQRVGPEHVVED 359

Query: 379 GDIVEIHAR 387
           GDIVEIH R
Sbjct: 360 GDIVEIHVR 368


>gi|11499729 GTP-binding protein [Archaeoglobus fulgidus]
           >gi|7428740|pir||B69518 GTP-binding protein DRG homolog
           - Archaeoglobus fulgidus >gi|2648391|gb|AAB89108.1|
           (AE000956) GTP-binding protein [Archaeoglobus fulgidus]
           Length = 355
           
 Score =  286 bits (723), Expect = 4e-76
 Identities = 157/367 (42%), Positives = 231/367 (62%), Gaps = 17/367 (4%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80
           +I ++IR LE+     P +K TE    ++K KLA LR+E EKQ+ +     +SL  KKEG
Sbjct: 5   SIEQQIRELEEEIKRTPYNKATEHHIGRLKAKLARLREEAEKQKAKAARQAFSL--KKEG 62

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140
            A  VL+G P+VGKS LL  LTG   E ADY FTT +P+P ++NYK   IQ+++VPG+IE
Sbjct: 63  DATAVLIGYPSVGKSTLLNKLTGAKSEVADYDFTTLKPVPGILNYKGASIQIIDVPGIIE 122

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200
           GAA G+G G ++++ +R AD I IV D+    +  + I+ RE    GI+++++ P + IR
Sbjct: 123 GAASGRGRGKEVISAVRVADLIIIVADVFN--LHTIDIVKRELYEGGIRLDQKPPDVVIR 180

Query: 201 RTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
           +   GG+ I+    +  D   +  +L+E KIHSA++ +RE +T+E   DAL  + V+  +
Sbjct: 181 KKERGGVRISSTVPLSIDEATITSVLKEYKIHSADVVIREDITIERLIDALAGNRVYIPS 240

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + NK D                +    I VSA+K INLD +KE +Y   E IRV+ K 
Sbjct: 241 LTVVNKIDLMDV------------DVADAIKVSAEKGINLDLLKEQIYRKLEFIRVYLKP 288

Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379
           PG +  +  P+ L+RG+TV D+  ++H+D V+NFRYA+VWGKSVKF GQRVG +HV+EDG
Sbjct: 289 PGGKVDFSEPMILRRGATVEDICRKLHRDFVENFRYAKVWGKSVKFDGQRVGLEHVVEDG 348

Query: 380 DIVEIHA 386
           DI+ I+A
Sbjct: 349 DIITIYA 355


>pir||E64465 GTP-binding protein DRG homolog - Methanococcus jannaschii
           >gi|1591967|gb|AAB99336.1| (U67573) GTP-binding protein,
           member of GTP1/OBG-family [Methanococcus jannaschii]
           Length = 391
           
 Score =  264 bits (668), Expect = 1e-69
 Identities = 146/367 (39%), Positives = 225/367 (60%), Gaps = 10/367 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I E+IR +E+     P +K T+K   ++K KLA+LR++   Q +   GGG   AVKK G 
Sbjct: 27  IEEEIRRIEEELKKTPYNKATQKHIGRLKAKLAKLREQA--QSRGGGGGGKGYAVKKSGD 84

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           A    VG P+VGKS LL  LT    E   Y FTT   +P ++ YK  +IQL++ PG+I G
Sbjct: 85  ATAAFVGFPSVGKSTLLNKLTNAKSEVGAYAFTTLTIVPGILEYKGAKIQLLDAPGIIVG 144

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           A+ GKG G ++L+ +R+AD I + +D+    +  + +L +E    GI++++  P ++I+ 
Sbjct: 145 ASSGKGRGTEVLSAVRSADLILLTVDIY--TLDHLPVLEKELYNVGIRLDQTPPDVKIKV 202

Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
              GGI ++    +   D + +  +L E +IH+A++ +RE +TLE F D +  + V+  +
Sbjct: 203 KERGGINVSSTVPLTHIDEDTIEAILNEYRIHNADVVIREDITLEQFIDVVAGNRVYIPS 262

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERF--KIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318
           +++ NK D   + + Y K +K   E F    I VS  K INLD +KE +Y+    I+++ 
Sbjct: 263 LVVVNKIDL--ADEEYLKYIKQKLEEFGKDYILVSGNKGINLDLLKEKIYEKLGFIKIYL 320

Query: 319 KSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377
           K  G++P +  P+ ++RG+TV DV E++HKD V+NFRYA+VWGKS K PGQRVG DH LE
Sbjct: 321 KPQGKKPDFDEPLIMRRGATVKDVCEKLHKDFVRNFRYAQVWGKSAKHPGQRVGLDHKLE 380

Query: 378 DGDIVEI 384
           DGDI+ I
Sbjct: 381 DGDILTI 387


>pir||F69083 GTP-binding protein DRG homolog - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622747|gb|AAB86094.1| (AE000921) GTP-binding
           protein, GTP1/OBG family  [Methanobacterium
           thermoautotrophicum]
           Length = 380
           
 Score =  249 bits (628), Expect = 5e-65
 Identities = 134/366 (36%), Positives = 222/366 (60%), Gaps = 11/366 (3%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I EKIR +E+     P +K T     ++K K++ L++E   QR+   G G    +KK G 
Sbjct: 19  IEEKIRKIEEEIQKTPYNKATAHHIGKLKAKISRLKEEA-LQRKTSSGKGRGFHIKKSGD 77

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           + +VL+G P+VGKS LL  LT  + +  DY FTT E +P +M Y+  QIQ+ ++PG+I G
Sbjct: 78  STVVLIGFPSVGKSTLLNELTSAESKVGDYQFTTLEIVPGVMEYRGAQIQIFDIPGIITG 137

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           A+ G+G G ++L+V R+AD I IV+D+       M I+LRE    GI+ N+  P + ++R
Sbjct: 138 ASRGRGRGREILSVARSADLIVIVLDVFN--TDHMDIILRELRDVGIRPNETPPDVIVKR 195

Query: 202 TPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
              GG+ ++  +E    D   +  +L E  IH+A++ +R+ +T++ F D ++ +  +  A
Sbjct: 196 RKLGGVKLSATVELTHLDEKIIRSVLNEYGIHNADVLIRDDITVDQFIDVMEANRAYIPA 255

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERF-KIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319
           I + NK D        E  ++   E+F + + +SA + IN+D ++E +++   +IR++ K
Sbjct: 256 ITVINKIDLVD-----ESYLEGLREKFPEALFISADRDINIDELREEIFNRLGLIRIYLK 310

Query: 320 SPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378
             G++  Y  P+ ++ GSTV DV +++H+D V+ FR+ARVWG SVKF GQ+VG +HVL D
Sbjct: 311 PQGKKADYDEPLIIREGSTVGDVCQKLHRDFVRKFRHARVWGSSVKFDGQKVGLEHVLND 370

Query: 379 GDIVEI 384
            D++ I
Sbjct: 371 EDVLRI 376


>gb|AAK42533.1| GTP binding conserved hypothetical protein [Sulfolobus
           solfataricus]
           Length = 351
           
 Score =  244 bits (617), Expect = 1e-63
 Identities = 163/390 (41%), Positives = 230/390 (58%), Gaps = 42/390 (10%)

Query: 1   MPTNVTAEYLAAEEEYRNAKTIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL 60
           M TN+ AE  A   +  +AKT  EK +AL++    VPKHKGTE L    KR++AELR+E+
Sbjct: 1   MVTNLPAEAKAKWLKVMDAKTPEEKFQALQEFLKEVPKHKGTENLVYWAKRRMAELREEM 60

Query: 61  EKQRQQRKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIP 120
           E  R+ +K GG+SL V+KEGA Q +L+G   + +S ++R LT V  E  + P      +P
Sbjct: 61  EV-RKSKKSGGFSLFVEKEGAGQAILIG-DMLLRSFIMRKLTNVKQEFNELP------VP 112

Query: 121 AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILL 180
            M+ Y+DVQIQLV  P   +   L K +G     +IRNAD + I I+  ED +  +K LL
Sbjct: 113 GMVKYEDVQIQLVNPP---KSLPLSKTIG-----LIRNADEVIIAINNKED-LSLIKSLL 163

Query: 181 REFERAGIKVNKRRPRIEIRRTPSG--GIVINGIENIKG-DINEVMKMLREEKIHSAEIT 237
              E   I + K + R+ I RT  G  GI +  +  + G D   V   +    I SA + 
Sbjct: 164 ---EDNNILLRKPKGRVVIERTRYGISGIRVVNLGKLIGIDEKVVRDYIESFGIKSAIVK 220

Query: 238 VREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKR 297
           +   VTL+D   ++ E++ +K  ++I        SKD ++      GE    +P+    +
Sbjct: 221 IIGEVTLDDIEKSMFEAVSYKPTVVI--------SKDRFDT-----GE----LPMLTIDQ 263

Query: 298 INLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYAR 357
           I  D + + L+D+ E+IRV+TK PGEEP   P+ LK+GSTVLDVA ++H  L +NFRYAR
Sbjct: 264 I--DKLPKHLFDMLEVIRVYTKEPGEEPTKDPLILKKGSTVLDVARKLHSSLAENFRYAR 321

Query: 358 VWGKSVKFPGQRVGPDHVLEDGDIVEIHAR 387
           VWGKSVKF GQ+VGP H+LED DIVEIH +
Sbjct: 322 VWGKSVKFQGQKVGPSHILEDRDIVEIHVK 351


>gb|AAF21162.1|AC010926_14 (AC010926) putative GTP-binding protein; 56356-53974 [Arabidopsis
           thaliana]
           Length = 399
           
 Score =  233 bits (587), Expect = 3e-60
 Identities = 134/368 (36%), Positives = 213/368 (57%), Gaps = 11/368 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I E+I+ +E   A   K+K TE    Q+K K+A+LR +L +  +   GGG    V K G 
Sbjct: 3   IVERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGSSGGGDGFEVTKYGH 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
            ++ L+G P+VGKS LL  LTG   E+A Y FTT   IP +++Y D +IQL+++PG+IEG
Sbjct: 63  GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           A+ GKG G Q++AV +++D + +V+D S+      +IL +E E  G+++NKR P+I  ++
Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKSE-GHRQILTKELEAVGLRLNKRPPQIYFKK 181

Query: 202 TPSGGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
             +GGI  N    + + D     ++L E KIH+AE+  RE  T++DF D ++ +  + K 
Sbjct: 182 KKTGGISFNTTTPLTRIDEKLCYQILHEYKIHNAEVLFREDATVDDFIDVVEGNRKYIKC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + NK D  G  D     V     +   I +S   ++NLD +   ++D   ++RV++K 
Sbjct: 242 VYVYNKIDVVGIDD-----VDRLARQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKP 296

Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376
             ++P +  P  L   + G TV D   ++H+ LVK+ +YA VWG S +   Q  G  H L
Sbjct: 297 QSQQPDFDEPFVLSADRGGCTVEDFCNQVHRTLVKDMKYALVWGTSARHYPQHCGLFHHL 356

Query: 377 EDGDIVEI 384
           ED D+V+I
Sbjct: 357 EDEDVVQI 364


>gb|AAF55688.1| (AE003727) CG6195 gene product [Drosophila melanogaster]
           Length = 363
           
 Score =  232 bits (585), Expect = 6e-60
 Identities = 135/366 (36%), Positives = 213/366 (57%), Gaps = 11/366 (3%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKEL-EKQRQQRKGGGYSLAVKKEG 80
           I EKI  +E+  A   K+K TE     +K KLA+ R +L E  ++  KG G+   V K G
Sbjct: 3   ILEKIAEIEREIARTQKNKATEYHLGLLKAKLAKYRSQLLEPSKKGEKGDGFD--VLKSG 60

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140
            A++ L+G P+VGKS +L  LT  + E+A+Y FTT   IP ++ Y+   IQL+++PG+IE
Sbjct: 61  DARVALIGFPSVGKSTMLSTLTKTESEAANYEFTTLTCIPGVIEYQGANIQLLDLPGIIE 120

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200
           GAA GKG G Q++AV R AD + +++D ++ P    ++L RE E  GI++NKR+P I  +
Sbjct: 121 GAAQGKGRGRQVIAVARTADLVLMMLDATK-PNVHRELLERELESVGIRLNKRKPNIYFK 179

Query: 201 RTPSGGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259
           +   GG+  N   ++ + +   V  +L   KI +AE+  RE  T ++F D +  + V+  
Sbjct: 180 QKKGGGLSFNATCSLTRCNEKMVQTILHSFKIFNAEVLFREDCTEDEFIDVVTANRVYLP 239

Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319
            + + NK D    ++     V     +   I VS   ++NLD + EAL++  ++IRV+TK
Sbjct: 240 CLYVYNKIDQISIEE-----VDRLARQPNSIVVSCNMKLNLDYMMEALWEALQLIRVYTK 294

Query: 320 SPGEEPAYPP-IALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378
            PG  P +   + L++G +V  V   IH+ L   F+YA VWG S K+  QRVG  HV+ D
Sbjct: 295 KPGAPPDFDDGLILRKGVSVEHVCHAIHRTLAAQFKYALVWGTSTKYSPQRVGIAHVMAD 354

Query: 379 GDIVEI 384
            D++++
Sbjct: 355 EDVIQV 360


>gb|AAF97313.1|AC007843_16 (AC007843) GTP binding protein [Arabidopsis thaliana]
           Length = 399
           
 Score =  230 bits (581), Expect = 2e-59
 Identities = 133/368 (36%), Positives = 210/368 (56%), Gaps = 11/368 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I E+I+ +E   A   K+K TE    Q+K K+A+LR +L +  +   GGG    V K G 
Sbjct: 3   IIERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGASGGGEGFEVTKYGH 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
            ++ L+G P+VGKS LL  LTG   E+A Y FTT   IP +++Y D +IQL+++PG+IEG
Sbjct: 63  GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           A+ GKG G Q++AV +++D + +V+D S+      +IL +E E  G+++NK  P+I  ++
Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKSE-GHRQILTKELEAVGLRLNKTPPQIYFKK 181

Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
             +GGI  N    +   D     ++L E KIH+AE+  RE  T++DF D ++ +  + K 
Sbjct: 182 KKTGGISFNTTAPLTHIDEKLCYQILHEYKIHNAEVLFRENATVDDFIDVIEGNRKYIKC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + NK D  G  D     V     +   I +S   ++NLD +   ++D   ++RV++K 
Sbjct: 242 VYVYNKIDVVGIDD-----VDRLSRQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKP 296

Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376
            G++P +  P  L   + G TV D    +H+ LVK+ +YA VWG S +   Q  G    L
Sbjct: 297 QGQQPDFDEPFVLSSDRGGCTVEDFCNHVHRTLVKDMKYALVWGTSTRHNPQNCGLSQHL 356

Query: 377 EDGDIVEI 384
           ED D+V+I
Sbjct: 357 EDEDVVQI 364


>sp|P43690|DRG1_XENLA DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN 1 (DRG 1) (XDRG)
           >gi|2120159|pir||I51426 GTP-binding protein DRG -
           African clawed frog >gi|433422|dbj|BAA02978.1| (D13865)
           GTP-binding protein DRG [Xenopus laevis]
           Length = 367
           
 Score =  229 bits (577), Expect = 5e-59
 Identities = 142/364 (39%), Positives = 210/364 (57%), Gaps = 10/364 (2%)

Query: 25  KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83
           +I  +E   A   K+K T      +K +LA+LR+EL   +    GG G    V K G A+
Sbjct: 7   RIAEIEAEMARTQKNKATAYHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           I  VG P+VGKS LL  L GV  E A Y FTT   +P ++ YK  +IQL+++PG+IEGA 
Sbjct: 67  IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVVRYKGAKIQLLDLPGIIEGAK 126

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203
            GKG G Q++AV R  + I IV+D+ + P+   KI+  E E  GI++NK+ P I  ++  
Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNKQPPNIGFKKKD 185

Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262
            GGI +       + D + V  +L E KIH+A+IT+R   T +D  D ++ + V+   I 
Sbjct: 186 KGGINLTATCAQSELDNDTVKSILAEYKIHNADITLRSDATADDLIDVVEGNRVYIPCIY 245

Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322
           + NK D    + + E+L   Y +    +P+SA  R N D + E ++D  +++R++TK  G
Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLQLVRIYTKPKG 300

Query: 323 EEPAY-PPIALKRGSTVL-DVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380
           + P Y  P+ L    T   D   +IHK+L+K F+YA VWG SVK   Q+VG DHVLED D
Sbjct: 301 QLPDYTSPVVLPCSHTAAEDFCTKIHKNLIKEFKYALVWGSSVKHNPQKVGKDHVLEDED 360

Query: 381 IVEI 384
           +++I
Sbjct: 361 VIQI 364


>pir||T39192 probable GTP-binding protein - fission yeast  (Schizosaccharomyces
           pombe) >gi|6014426|emb|CAB57425.1| (AL121764) putative
           GTP-binding protein [Schizosaccharomyces pombe]
           Length = 366
           
 Score =  228 bits (576), Expect = 7e-59
 Identities = 131/369 (35%), Positives = 208/369 (55%), Gaps = 13/369 (3%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80
           T  +KI+ +E   A   K+K T K    +K KLA+L++EL        GGG    V + G
Sbjct: 3   TTAQKIKEVEDEMAKTQKNKATAKHLGMLKAKLAKLKRELITPTGGGGGGGLGFDVARTG 62

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140
              +  +G P+VGKS L+  LTG   E+A Y FTT   +P ++ Y   +IQ++++PG+IE
Sbjct: 63  IGTVGFIGFPSVGKSTLMTQLTGTRSEAAAYEFTTLTTVPGVLQYNGAKIQILDLPGIIE 122

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200
           GA  G+G G Q++ V R  + I IV+D+ + P+   +I+  E E  GI++NK  P I  +
Sbjct: 123 GAKDGRGRGKQVITVARTCNLIFIVLDVLK-PMSHKRIIEEELEGFGIRLNKEPPNIVFK 181

Query: 201 RTPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259
           +   GGI + N +     D++E+  +  E +++SA+I  R   T++D  D L+ + V+  
Sbjct: 182 KKERGGINITNTVPLTHIDLDEIRAVCSEYRVNSADIAFRCDATIDDLIDVLEGNRVYIP 241

Query: 260 AIIIANKGDAPGSK--DNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVF 317
           A+ + NK D+   +  D  +++  A       +P+   +  N+D +KE ++D   ++RV+
Sbjct: 242 ALYVLNKIDSISIEELDLIDRIPNA-------VPICGNRGWNIDELKETMWDYLNLVRVY 294

Query: 318 TKSPGEEPAY-PPIALKRG-STVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375
           T+  G EP Y  P+ L+ G STV D    IH  +   F++A VWGKSV +PG RVG  HV
Sbjct: 295 TRPRGLEPDYSEPVILRTGHSTVEDFCNNIHSSIKSQFKHAYVWGKSVPYPGMRVGLSHV 354

Query: 376 LEDGDIVEI 384
           L D D+V I
Sbjct: 355 LLDEDVVTI 363


>pir||T42381 probable GTP-binding protein - fission yeast  (Schizosaccharomyces
           pombe) >gi|1749478|dbj|BAA13797.1| (D89135) similar to
           Xenopus laevis developing GTP-binding protein DRG,
           SWISS-PROT Accession Number P43690 [Schizosaccharomyces
           pombe]
           Length = 366
           
 Score =  228 bits (574), Expect = 1e-58
 Identities = 131/369 (35%), Positives = 208/369 (55%), Gaps = 13/369 (3%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80
           T  +KI+ +E   A   K+K T K    +K KLA+L++EL        GGG    V + G
Sbjct: 3   TTAQKIKEVEDEMAKTQKNKATAKHLGMLKAKLAKLKRELITPTGGGGGGGLGFDVARTG 62

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140
              +  +G P+VGKS L+  LTG   E+A Y FTT   +P ++ Y   +IQ++++PG+IE
Sbjct: 63  IGTVGFIGFPSVGKSTLMTQLTGTRSEAAAYEFTTLTTVPGVLQYNGAKIQILDLPGIIE 122

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200
           GA  G+G G Q++ V R  + I IV+D+ + P+   +I+  E E  GI++NK  P I  +
Sbjct: 123 GAKDGRGRGKQVITVARTCNLIFIVLDVLK-PMSHKRIIEEELEGFGIRLNKEPPNIVFK 181

Query: 201 RTPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259
           +   GGI + N +     D++E+  +  E +++SA+I  R   T++D  D L+ + V+  
Sbjct: 182 KKERGGINITNTVPLTHIDLDEIRAVCSEYRVNSADIAFRCDSTIDDLIDVLEGNRVYIP 241

Query: 260 AIIIANKGDAPGSK--DNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVF 317
           A+ + NK D+   +  D  +++  A       +P+   +  N+D +KE ++D   ++RV+
Sbjct: 242 ALYVLNKIDSISIEELDLIDRIPNA-------VPICGNRGWNIDELKETMWDYLNLVRVY 294

Query: 318 TKSPGEEPAY-PPIALKRG-STVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375
           T+  G EP Y  P+ L+ G STV D    IH  +   F++A VWGKSV +PG RVG  HV
Sbjct: 295 TRPRGLEPDYSEPVILRTGHSTVEDFCNNIHSSIKSQFKHAYVWGKSVPYPGMRVGLSHV 354

Query: 376 LEDGDIVEI 384
           L D D+V I
Sbjct: 355 LLDEDVVTI 363


>gi|4758796 developmentally regulated GTP-binding protein 1; neural precursor
           cell expressed, developmentally down-regulated 3 [Homo
           sapiens] >gi|6685390|sp|Q9Y295|DRG1_HUMAN
           DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN 1 (DRG 1)
           >gi|4127988|emb|CAA06775.1| (AJ005940) GTP-binding
           protein [Homo sapiens] >gi|4218945|gb|AAD12240.1|
           (AF078103) developmentally regulated GTP-binding protein
           [Homo sapiens]
           Length = 367
           
 Score =  228 bits (574), Expect = 1e-58
 Identities = 140/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%)

Query: 25  KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83
           KI  +E   A   K+K T      +K +LA+LR+EL   +    GG G    V K G A+
Sbjct: 7   KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           I  VG P+VGKS LL  L GV  E A Y FTT   +P ++ YK  +IQL+++PG+IEGA 
Sbjct: 67  IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 126

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203
            GKG G Q++AV R  + I IV+D+ + P+   KI+  E E  GI++N + P I  ++  
Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 185

Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262
            GGI +       + D   V  +L E KIH+A++T+R   T +D  D ++ + V+   I 
Sbjct: 186 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIY 245

Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322
           + NK D    + + E+L   Y +    +P+SA  R N D + E ++D  +++R++TK  G
Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 300

Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380
           + P Y  P +     +TV D   +IHK+L+K F+YA VWG SVK   Q+VG DH LED D
Sbjct: 301 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 360

Query: 381 IVEI 384
           +++I
Sbjct: 361 VIQI 364


>gi|11417999 developmentally regulated GTP-binding protein 1 [Homo sapiens]
           Length = 389
           
 Score =  228 bits (574), Expect = 1e-58
 Identities = 140/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%)

Query: 25  KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83
           KI  +E   A   K+K T      +K +LA+LR+EL   +    GG G    V K G A+
Sbjct: 29  KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 88

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           I  VG P+VGKS LL  L GV  E A Y FTT   +P ++ YK  +IQL+++PG+IEGA 
Sbjct: 89  IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 148

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203
            GKG G Q++AV R  + I IV+D+ + P+   KI+  E E  GI++N + P I  ++  
Sbjct: 149 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 207

Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262
            GGI +       + D   V  +L E KIH+A++T+R   T +D  D ++ + V+   I 
Sbjct: 208 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIY 267

Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322
           + NK D    + + E+L   Y +    +P+SA  R N D + E ++D  +++R++TK  G
Sbjct: 268 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 322

Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380
           + P Y  P +     +TV D   +IHK+L+K F+YA VWG SVK   Q+VG DH LED D
Sbjct: 323 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 382

Query: 381 IVEI 384
           +++I
Sbjct: 383 VIQI 386


>gi|6681225 developmentally regulated GTP-binding protein 1 [Mus musculus]
           >gi|416914|sp|P32233|DRG1_MOUSE DEVELOPMENTALLY
           REGULATED GTP-BINDING PROTEIN 1 (DRG 1) (NEDD3 PROTEIN)
           >gi|220507|dbj|BAA01555.1| (D10715) GTP-binding protein
           [Mus musculus]
           Length = 367
           
 Score =  228 bits (574), Expect = 1e-58
 Identities = 140/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%)

Query: 25  KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83
           KI  +E   A   K+K T      +K +LA+LR+EL   +    GG G    V K G A+
Sbjct: 7   KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           I  VG P+VGKS LL  L GV  E A Y FTT   +P ++ YK  +IQL+++PG+IEGA 
Sbjct: 67  IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 126

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203
            GKG G Q++AV R  + I IV+D+ + P+   KI+  E E  GI++N + P I  ++  
Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 185

Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262
            GGI +       + D   V  +L E KIH+A++T+R   T +D  D ++ + V+   I 
Sbjct: 186 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIY 245

Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322
           + NK D    + + E+L   Y +    +P+SA  R N D + E ++D  +++R++TK  G
Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 300

Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380
           + P Y  P +     +TV D   +IHK+L+K F+YA VWG SVK   Q+VG DH LED D
Sbjct: 301 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 360

Query: 381 IVEI 384
           +++I
Sbjct: 361 VIQI 364


>gb|AAB53256.1| (U66408) GTP-binding protein [Arabidopsis thaliana]
           >gi|2345150|gb|AAB67830.1| (AF014822) developmentally
           regulated GTP binding protein [Arabidopsis thaliana]
           Length = 399
           
 Score =  227 bits (572), Expect = 2e-58
 Identities = 132/368 (35%), Positives = 209/368 (55%), Gaps = 11/368 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I E+I+ +E   A   K+K TE    Q+K K+A+LR +L +  +   GGG    V K G 
Sbjct: 3   IIERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGASGGGEGFEVTKYGH 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
            ++ L+G P+VGKS LL  LTG   E+A Y FTT   IP +++Y D +IQL+++PG+IEG
Sbjct: 63  GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           A+ GKG G Q++AV +++D + +V+D S+      +IL +E E  G+++NK  P+I  ++
Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKSE-GHRQILTKELEAVGLRLNKTPPQIYFKK 181

Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
             +GGI  N    +   D     ++L E KIH+AE+  RE  T++DF D ++ +  + K 
Sbjct: 182 KKTGGISFNTTAPLTHIDEKLCYQILHEYKIHNAEVLFRENATVDDFIDVIEGNRKYIKC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + +  K D  G  D     V     +   I +S   ++NLD +   ++D   ++RV++K 
Sbjct: 242 VYVYIKIDVVGIDD-----VDRLSRQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKP 296

Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376
            G++P +  P  L   + G TV D    +H+ LVK+ +YA VWG S +   Q  G    L
Sbjct: 297 QGQQPDFDEPFVLSSDRGGCTVEDFCNHVHRTLVKDMKYALVWGTSTRHNPQNCGLSQHL 356

Query: 377 EDGDIVEI 384
           ED D+V+I
Sbjct: 357 EDEDVVQI 364


>pir||JC1349 GTP-binding protein DRG [validated] - mouse
           Length = 367
           
 Score =  226 bits (570), Expect = 3e-58
 Identities = 139/364 (38%), Positives = 208/364 (56%), Gaps = 10/364 (2%)

Query: 25  KIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG-GYSLAVKKEGAAQ 83
           KI  +E   A   K+K T      +K +LA+LR+EL   +    GG G    V K G A+
Sbjct: 7   KIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDAR 66

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           I  VG P+VGKS LL  L GV  E A Y FTT   +P ++ YK  +IQL+++PG+IEGA 
Sbjct: 67  IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 126

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203
            GKG G Q++AV R  + I IV+D+ + P+   KI+  E E  GI++N + P I  ++  
Sbjct: 127 DGKGRGRQVIAVARTCNLILIVLDVLK-PLGHKKIIENELEGFGIRLNSKPPNIGFKKKD 185

Query: 204 SGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262
            GGI +       + D   V  +L E KIH+A++T+R   T ++  D ++ + V+   I 
Sbjct: 186 KGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADELIDVVEGNRVYIPCIY 245

Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322
           + NK D    + + E+L   Y +    +P+SA  R N D + E ++D  +++R++TK  G
Sbjct: 246 VLNKID----QISIEELDIIY-KVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 300

Query: 323 EEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380
           + P Y  P +     +TV D   +IHK+L+K F+YA VWG SVK   Q+VG DH LED D
Sbjct: 301 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 360

Query: 381 IVEI 384
           +++I
Sbjct: 361 VIQI 364


>emb|CAC12607.1| (AL445067) GTP-binding protein [Thermoplasma acidophilum]
           Length = 360
           
 Score =  225 bits (568), Expect = 6e-58
 Identities = 136/369 (36%), Positives = 215/369 (57%), Gaps = 14/369 (3%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79
           TI E+I+ +E        +K TE     +K K+A+L+ E         GG +S  AV K 
Sbjct: 3   TIEERIKEIEDEIKRTQYNKATEHHIGLLKAKIAKLQMEASASH----GGSHSGFAVPKS 58

Query: 80  GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139
           G A + LVG PNVGKS LL  LT  + E  DY FTT +PIP ++ YK  +IQ++++PG+I
Sbjct: 59  GDATVALVGFPNVGKSSLLNRLTNSESEIGDYAFTTLQPIPGILEYKGAEIQILDLPGII 118

Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199
           E A+ G   G ++L+ +R AD I IV D+    I +   +L E   AGI VN++R  +EI
Sbjct: 119 ENASYGSARGREILSAVRAADLIVIVTDVQAGGIDK---ILTELYNAGIVVNRKRRNVEI 175

Query: 200 RRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259
           R+T SGGI ++  +N+  D + + ++++E K+ +A++ +RE V++ED  + L    V+  
Sbjct: 176 RKTTSGGIRLHRPKNVDIDEDYIKEIMKEFKLVNADVYIRENVSVEDIIETLQGRYVYIP 235

Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319
           +I+  NK D   S D  +  V  YGE F+   VSAK    ++ +KE ++    +IR++ +
Sbjct: 236 SIVAVNKIDMNPSFDTSQ--VSQYGEVFR---VSAKTGYGIEELKEGIFRSLNLIRIYLR 290

Query: 320 S-PGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378
           +  G      P+ ++ G+TV +V  +I++ ++ +FRYA V GK+     QRVG D+ L D
Sbjct: 291 NKAGVVDFQKPLIVREGTTVREVCRKINRSMIDSFRYAIVSGKNRPIGEQRVGIDYPLMD 350

Query: 379 GDIVEIHAR 387
            DIV I +R
Sbjct: 351 EDIVTIISR 359


>gb|AAF79465.1|AC022492_9 (AC022492) F1L3.17 [Arabidopsis thaliana]
           Length = 412
           
 Score =  224 bits (566), Expect = 1e-57
 Identities = 133/380 (35%), Positives = 210/380 (55%), Gaps = 22/380 (5%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I E+I+ +E   A   K+K TE    Q+K K+A+LR +L +  +   GGG    V K G 
Sbjct: 3   IIERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGASGGGEGFEVTKYGH 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
            ++ L+G P+VGKS LL  LTG   E+A Y FTT   IP +++Y D +IQL+++PG+IEG
Sbjct: 63  GRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPI------------KQMKILLREFERAGIK 189
           A+ GKG G Q++AV +++D + +V+D S+                  +IL +E E  G++
Sbjct: 123 ASEGKGRGRQVIAVAKSSDLVLMVLDASKVSYGLYVHVNWYMSEGHRQILTKELEAVGLR 182

Query: 190 VNKRRPRIEIRRTPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFA 248
           +NK  P+I  ++  +GGI  N    +   D     ++L E KIH+AE+  RE  T++DF 
Sbjct: 183 LNKTPPQIYFKKKKTGGISFNTTAPLTHIDEKLCYQILHEYKIHNAEVLFRENATVDDFI 242

Query: 249 DALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALY 308
           D ++ +  + K + + NK D  G  D     V     +   I +S   ++NLD +   ++
Sbjct: 243 DVIEGNRKYIKCVYVYNKIDVVGIDD-----VDRLSRQPNSIVISCNLKLNLDRLLARMW 297

Query: 309 DVAEIIRVFTKSPGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVK 364
           D   ++RV++K  G++P +  P  L   + G TV D    +H+ LVK+ +YA VWG S +
Sbjct: 298 DEMGLVRVYSKPQGQQPDFDEPFVLSSDRGGCTVEDFCNHVHRTLVKDMKYALVWGTSTR 357

Query: 365 FPGQRVGPDHVLEDGDIVEI 384
              Q  G    LED D+V+I
Sbjct: 358 HNPQNCGLSQHLEDEDVVQI 377


>pir||T09368 GTP-binding protein F23K16.150 - Arabidopsis thaliana
           >gi|5042168|emb|CAB44687.1| (AL078620) GTP-binding-like
           protein [Arabidopsis thaliana]
           >gi|7270936|emb|CAB80615.1| (AL161595) GTP-binding-like
           protein [Arabidopsis thaliana]
           Length = 369
           
 Score =  224 bits (564), Expect = 2e-57
 Identities = 134/369 (36%), Positives = 206/369 (55%), Gaps = 11/369 (2%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS--LAVKK 78
           TI +KI+ +E   A   K+K T      +K KLA+LR++L     +  GGG      V K
Sbjct: 3   TIMQKIKEIEDEMAKTQKNKATSHHLGLLKAKLAKLRRDLLAPPTKGGGGGAGEGFDVTK 62

Query: 79  EGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGL 138
            G +++ LVG P+VGKS LL  LTG   E A Y FTT   IP ++ Y+  +IQL+++PG+
Sbjct: 63  SGDSRVGLVGFPSVGKSTLLNKLTGTFSEVASYEFTTLTCIPGVITYRGAKIQLLDLPGI 122

Query: 139 IEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIE 198
           IEGA  GKG G Q+++  R  + I IV+D  + PI   +++ +E E  GI++NK  P + 
Sbjct: 123 IEGAKDGKGRGRQVISTARTCNCILIVLDAIK-PITHKRLIEKELEGFGIRLNKEPPNLT 181

Query: 199 IRRTPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVW 257
            R+   GGI +     +   D++ V  +  E ++H+A+IT+R   T +D  D ++ S ++
Sbjct: 182 FRKKDKGGINLTSTVAVTHLDLDTVKAICGEYRMHNADITLRYDATADDLIDVIEGSRIY 241

Query: 258 KKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVF 317
              I   NK D+   ++     ++   +     PVSA    NLD + + +++  ++ R++
Sbjct: 242 MPCIYAVNKIDSITLEE-----LEILDKLPHYCPVSAHLEWNLDGLLDKIWEYLDLTRIY 296

Query: 318 TKSPGEEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375
           TK     P Y  P I   +  TV D   RIHKD++K F+YA VWG S K   QRVG +H 
Sbjct: 297 TKPKAMNPDYDDPVILSSKKRTVEDFCIRIHKDMLKQFKYALVWGSSAKHKPQRVGKEHE 356

Query: 376 LEDGDIVEI 384
           LED D+V+I
Sbjct: 357 LEDEDVVQI 365


>gb|AAF58591.1| (AE003823) 128up gene product [Drosophila melanogaster]
           Length = 368
           
 Score =  224 bits (564), Expect = 2e-57
 Identities = 138/368 (37%), Positives = 209/368 (56%), Gaps = 10/368 (2%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79
           TI EKI A+E   A   K+K T      +K KLA+LR+EL   +    G G +   V K 
Sbjct: 3   TILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGGGGTGEAGFEVAKT 62

Query: 80  GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139
           G A++  VG P+VGKS LL  L GV  E A Y FTT   +P  + YK  +IQL+++PG+I
Sbjct: 63  GDARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGII 122

Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199
           EGA  GKG G Q++AV R  + I +V+D  + P+   K+L  E E  GI++NK+ P I  
Sbjct: 123 EGAKDGKGRGRQVIAVARTCNLIFMVLDCLK-PLGHKKLLEHELEGFGIRLNKKPPNIYY 181

Query: 200 RRTPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWK 258
           +R   GGI +N  +   + D + V  +L E KIH+A+IT+R   T +D  D ++ + ++ 
Sbjct: 182 KRKDKGGINLNSMVPQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYI 241

Query: 259 KAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318
             I + NK D    + + E+L   Y +    +P+SA    N D + E +++   + R++T
Sbjct: 242 PCIYLLNKID----QISIEELDVIY-KIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYT 296

Query: 319 KSPGEEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376
           K  G+ P Y  P +     +++ D   ++H+ + K F+YA VWG SVK   Q+VG +HVL
Sbjct: 297 KPKGQLPDYNSPVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVL 356

Query: 377 EDGDIVEI 384
            D D+V+I
Sbjct: 357 NDEDVVQI 364


>pir||T43254 GTP-binding protein - Thermoplasma acidophilum
           >gi|1698846|gb|AAC44620.1| (U72850) GTP-binding protein
           [Thermoplasma acidophilum]
           Length = 360
           
 Score =  223 bits (563), Expect = 2e-57
 Identities = 135/369 (36%), Positives = 214/369 (57%), Gaps = 14/369 (3%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79
           TI E+I+ +E        +K TE     +K K+A+L+ E         GG +S  AV K 
Sbjct: 3   TIEERIKEIEDEIKRTQYNKATEHHIGLLKAKIAKLQMEASASH----GGSHSGFAVPKS 58

Query: 80  GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139
           G A + LVG PNVGKS LL  LT  + E  DY FTT +PIP ++ YK  +IQ++++PG+I
Sbjct: 59  GDATVALVGFPNVGKSSLLNRLTNSESEIGDYAFTTLQPIPGILEYKGAEIQILDLPGII 118

Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199
           E A+ G   G ++L+ +R AD I IV D+    I +   +L E   AGI VN++R  +EI
Sbjct: 119 ENASYGSARGREILSAVRAADLIVIVTDVQAGGIDK---ILTELYNAGIVVNRKRRNVEI 175

Query: 200 RRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259
           R+T SGGI ++  +N+  D + + ++++E K+ +A++ +RE V++ED  + L    V+  
Sbjct: 176 RKTTSGGIRLHRPKNVDIDEDYIKEIMKEFKLVNADVYIRENVSVEDIIETLQGRYVYIP 235

Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319
           +I+  NK D   S D  +  V  YGE F+   VSAK    ++ +KE ++    +IR++ +
Sbjct: 236 SIVAVNKIDMNPSFDTSQ--VSQYGEVFR---VSAKTGYGIEELKEGIFRSLNLIRIYLR 290

Query: 320 S-PGEEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLED 378
           +  G      P+ ++ G+TV +V  +I++ ++ +FRYA V GK+      RVG D+ L D
Sbjct: 291 NKAGVVDFQKPLIVREGTTVREVCRKINRSMIDSFRYAIVSGKNRPIGEHRVGIDYPLMD 350

Query: 379 GDIVEIHAR 387
            DIV I +R
Sbjct: 351 EDIVTIISR 359


>gi|10946678 developmentally regulated GTP-binding protein 2 [Mus musculus]
           >gi|8928105|sp|Q9QXB9|DRG2_MOUSE DEVELOPMENTALLY
           REGULATED GTP-BINDING PROTEIN 2 (DRG 2)
           >gi|6688758|emb|CAB65258.1| (AJ243590) GTP-binding
           protein [Mus musculus]
           Length = 364
           
 Score =  221 bits (558), Expect = 9e-57
 Identities = 126/365 (34%), Positives = 202/365 (54%), Gaps = 8/365 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I EKI  +EK  A   K+K TE     +K KLA+ R +L +  +     G    V K G 
Sbjct: 3   ILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGD 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           A++ L+G P+VGKS  L  +T    E+A Y FTT   IP ++ YK   IQL+++PG+IEG
Sbjct: 63  ARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           AA G+G G Q++AV R AD + +++D ++  + Q  +L +E E  GI++NK +P I  + 
Sbjct: 123 AAQGRGRGRQVIAVARTADVVVMMLDATKGDV-QRSLLEKELESVGIRLNKHKPNIYFKP 181

Query: 202 TPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
              GGI  N    +     +++++ L E KI +AE+  RE  + +DF D +  + V+   
Sbjct: 182 KKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDDFIDVIVGNRVYMPC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + NK D    ++     V     +   + +S   ++NLD + E L++   +  ++TK 
Sbjct: 242 LYVYNKIDQISMEE-----VDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKK 296

Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379
            G+ P +   I L++G++V  V  RIH+ L   F+YA VWG S K+  QRVG  H +E  
Sbjct: 297 RGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHE 356

Query: 380 DIVEI 384
           D+++I
Sbjct: 357 DVIQI 361


>gi|4557537 developmentally regulated GTP-binding protein 2 [Homo sapiens]
           >gi|1706518|sp|P55039|DRG2_HUMAN DEVELOPMENTALLY
           REGULATED GTP-BINDING PROTEIN 2 (DRG 2)
           >gi|1082424|pir||A55014 GTP-binding protein DRG homolog
           - human >gi|577779|emb|CAA56730.1| (X80754) GTP-binding
           protein [Homo sapiens]
           Length = 364
           
 Score =  221 bits (557), Expect = 1e-56
 Identities = 127/365 (34%), Positives = 202/365 (54%), Gaps = 8/365 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I EKI  +EK  A   K+K TE     +K KLA+ R +L +  +     G    V K G 
Sbjct: 3   ILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGD 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           A++ L+G P+VGKS  L  +T    E+A Y FTT   IP ++ YK   IQL+++PG+IEG
Sbjct: 63  ARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           AA GKG G Q++AV R AD I +++D ++  + Q  +L +E E  GI++NK +P I  + 
Sbjct: 123 AAQGKGRGRQVIAVARTADVIIMMLDATKGEV-QRSLLEKELESVGIRLNKHKPNIYFKP 181

Query: 202 TPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
              GGI  N    +     +++++ L E KI +AE+  RE  + ++F D +  + V+   
Sbjct: 182 KKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + NK D    ++     V     +   + +S   ++NLD + E L++   +  ++TK 
Sbjct: 242 LYVYNKIDQISMEE-----VDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKK 296

Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379
            G+ P +   I L++G++V  V  RIH+ L   F+YA VWG S K+  QRVG  H +E  
Sbjct: 297 RGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHE 356

Query: 380 DIVEI 384
           D+++I
Sbjct: 357 DVIQI 361


>sp|P32234|128U_DROME GTP-BINDING PROTEIN 128UP >gi|422452|pir||S33467 GTP-binding
           protein 128up - fruit fly (Drosophila melanogaster)
           >gi|630861|pir||S42582 GTP-binding protein 128up - fruit
           fly (Drosophila melanogaster) >gi|311343|emb|CAA50701.1|
           (X71866) GTP-binding protein [Drosophila melanogaster]
           Length = 368
           
 Score =  220 bits (556), Expect = 2e-56
 Identities = 136/368 (36%), Positives = 208/368 (55%), Gaps = 10/368 (2%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKE 79
           TI EKI A+E   A   K+K T      +K  +A+LR+EL   +    G G +   V K 
Sbjct: 3   TILEKISAIESEMARTQKNKATSAHLGLLKANVAKLRRELISPKGGGGGTGEAGFEVAKT 62

Query: 80  GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLI 139
           G A++  VG P+VGKS LL  L GV  E A Y FTT   +P  + YK  +IQL+++PG+I
Sbjct: 63  GDARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGII 122

Query: 140 EGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEI 199
           EGA  GKG G Q++AV R  + I +V+D  + P+   K+L  E E  GI++NK+ P I  
Sbjct: 123 EGAKDGKGRGRQVIAVARTCNLIFMVLDCLK-PLGHKKLLEHELEGFGIRLNKKPPNIYY 181

Query: 200 RRTPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWK 258
           +R   GGI +N  +   + D + V  +L E KIH+A+IT+R   T +D  D ++ + ++ 
Sbjct: 182 KRKDKGGINLNSMVPQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYI 241

Query: 259 KAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318
             I + NK D    + + E+L   Y +    +P+SA    N D + E +++   + R++T
Sbjct: 242 PCIYLLNKID----QISIEELDVIY-KIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYT 296

Query: 319 KSPGEEPAY--PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376
           K  G+ P Y  P +     +++ D   ++H+ + K F+YA VWG SVK   Q+VG +HVL
Sbjct: 297 KPKGQLPDYNSPVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVL 356

Query: 377 EDGDIVEI 384
            D D+V+I
Sbjct: 357 NDEDVVQI 364


>gi|6319281 similar to Xenopus GTP-binding protein DRG; Fun11p [Saccharomyces
           cerevisiae] >gi|731276|sp|P39729|YAD6_YEAST HYPOTHETICAL
           40.7 KD PROTEIN IN PYK1-SNC1 INTERGENIC REGION
           >gi|1077475|pir||S51983 FUN11 protein - yeast
           (Saccharomyces cerevisiae) >gi|595548|gb|AAC04995.1|
           (U12980) Fun11p [Saccharomyces cerevisiae]
           Length = 369
           
 Score =  220 bits (556), Expect = 2e-56
 Identities = 136/370 (36%), Positives = 215/370 (57%), Gaps = 12/370 (3%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLA--VKK 78
           T  EKI+A+E   A   K+K T     Q+K KLA+LR+EL        GGG  +   V +
Sbjct: 3   TTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVAR 62

Query: 79  EGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGL 138
            G A +  VG P+VGKS LL  LTG + E+A+Y FTT   +P ++ YK  +IQ++++PG+
Sbjct: 63  TGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTVPGVIRYKGAKIQMLDLPGI 122

Query: 139 IEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIE 198
           I+GA  G+G G Q++AV R  + + I++D+++ P+   +I+ +E E  GI++NK  P I 
Sbjct: 123 IDGAKDGRGRGKQVIAVARTCNLLFIILDVNK-PLHHKQIIEKELEGVGIRLNKTPPDIL 181

Query: 199 IRRTPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALD-ESLV 256
           I++   GGI + N +       +E+  ++ E +I+SAEI  R   T++D  D L+  S  
Sbjct: 182 IKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRR 241

Query: 257 WKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRV 316
           +  AI + NK D+  S +  E L +        +P+S+ +  NLD + + ++D   ++R+
Sbjct: 242 YMPAIYVLNKIDSL-SIEELELLYRIP----NAVPISSGQDWNLDELLQVMWDRLNLVRI 296

Query: 317 FTKSPGEEPAY-PPIALKRG-STVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDH 374
           +TK  G+ P +  P+ L+    +V D   +IHK LV +FR A V+G SVK   Q VG  H
Sbjct: 297 YTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDDFRNALVYGSSVKHQPQYVGLSH 356

Query: 375 VLEDGDIVEI 384
           +LED D+V I
Sbjct: 357 ILEDEDVVTI 366


>gb|AAC33135.1| (AF035177) GTP-binding protein [Oncorhynchus tshawytscha]
           Length = 364
           
 Score =  220 bits (556), Expect = 2e-56
 Identities = 127/365 (34%), Positives = 209/365 (56%), Gaps = 8/365 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I EKI  +E+  +   K+K TE     +K KLA+ R +L +  +     G    V K G 
Sbjct: 3   ILEKIGEIEREISRTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSAGAKGEGFDVMKSGD 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           A++ L+G P+VGKS  L  +T    E+A Y FTT   IP ++ Y    IQL+++PG+IEG
Sbjct: 63  ARVALIGFPSVGKSTFLSLMTATASEAASYEFTTLTCIPGVIEYNGANIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           A+ GKG G Q++AV R AD + +++D ++  + Q K+L +E E  GI++N+ +P I  + 
Sbjct: 123 ASQGKGRGRQVIAVARTADVVIMMLDATKGDV-QRKLLEKELESVGIRLNRSKPNIYFKP 181

Query: 202 TPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
              GG+  N +  +     +++++ L E KI +AE+  RE  T +DF D +  + V+   
Sbjct: 182 KKGGGLSYNSMVPLTMCSEKLVQLILHEYKIFNAEVLFREDSTPDDFIDVIVGNRVYMPC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + NK D    + + E++ +   E   ++ +S   ++NLD + E L++   +I ++TK 
Sbjct: 242 LYVYNKVD----QISIEEVDRLAHEPHSVV-ISCGMKLNLDFLLERLWEYLALICLYTKK 296

Query: 321 PGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDG 379
            GE P +   I ++RG++V  V  RIH+ L   F+YA VWG S KF  QRVG  H++E  
Sbjct: 297 RGERPDFSDAIIMRRGASVEHVCHRIHRTLASQFKYALVWGTSTKFDPQRVGLTHIMEHE 356

Query: 380 DIVEI 384
           D+++I
Sbjct: 357 DVIQI 361


>pir||T31553 hypothetical protein T28D6.6 - Caenorhabditis elegans
           >gi|5832862|emb|CAB55097.1| (AL117202) contains
           similarity to Pfam domain: PF01018 (GTP1/OBG family),
           Score=576.0, E-value=7.7e-170, N=1~cDNA EST yk64c12.3
           comes from this gene~cDNA EST yk151h4.3 comes from this
           gene~cDNA EST yk211a3.3 comes from this gene~cDNA EST
           yk466c6.3 come> >gi|6018399|emb|CAB57908.1| (Z81134)
           contains similarity to Pfam domain: PF01018 (GTP1/OBG
           family), Score=576.0, E-value=7.7e-170, N=1~cDNA EST
           yk64c12.3 comes from this gene~cDNA EST yk151h4.3 comes
           from this gene~cDNA EST yk211a3.3 comes from this
           gene~cDNA EST yk466c6.3 comes >
           Length = 366
           
 Score =  220 bits (555), Expect = 2e-56
 Identities = 138/367 (37%), Positives = 210/367 (56%), Gaps = 9/367 (2%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80
           ++ +KI  +E   A   K+K T      +K KLA+LR++L   +    G G    V K G
Sbjct: 2   SVLQKIADIEAEMARTQKNKATNAHLGILKAKLAKLRRDLITPKGGGGGPGEGFDVAKTG 61

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140
            A+I  VG P+VGKS LL  L GV  E A Y FTT   +P ++ YK  +IQL+++PG+IE
Sbjct: 62  DARIGFVGFPSVGKSTLLCNLAGVFSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIE 121

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200
           GA  GKG G Q++AV R    I +V+D+ + P++  K+L  E E  GI++NK+ P I  +
Sbjct: 122 GAKDGKGRGKQVIAVARTCSLILMVLDVMK-PLQHKKLLEYELEGFGIRLNKQPPNIGYK 180

Query: 201 RTPSGGIVING-IENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKK 259
           R   GGI +   +   + D++ V  +L E +IH+A+IT+R   T ED  D ++ + ++  
Sbjct: 181 RKEKGGINLTMLVPQSELDLDLVKSILAEYRIHNADITLRYDATSEDLIDVIEGNRIYIP 240

Query: 260 AIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTK 319
            I + NK D    + + E+L   Y      +P+SA  + N D + E +++   +IR++TK
Sbjct: 241 CIYVLNKID----QISIEELDIIY-RIPHTVPISAHHKWNFDDLLEKVWEYLNLIRIYTK 295

Query: 320 SPGEEPAY-PPIALK-RGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377
             G+ P Y  PI L     ++ D+  +IHK L K+F+ A VWG S K   QRVG DHVL 
Sbjct: 296 PKGQLPDYSQPIVLNAERKSIEDLCTKIHKSLQKDFKCALVWGASAKHNPQRVGRDHVLI 355

Query: 378 DGDIVEI 384
           D D+V++
Sbjct: 356 DEDVVQV 362


>sp|P17103|YRB1_HALCU HYPOTHETICAL 40 KD GTP-BINDING PROTEIN IN RIBOSOMAL PROTEIN GENE
           CLUSTER 5'REGION >gi|76329|pir||QQHS4C GTP-binding
           protein DRG homolog - Halobacterium salinarum  (strain
           cutirubrum) >gi|43450|emb|CAA33176.1| (X15078) ORF
           protein [Halobacterium cutirubrum]
           >gi|10580655|gb|AAG19503.1| (AE005042) GTP-binding
           protein DRG; Drg [Halobacterium sp. NRC-1]
           Length = 370
           
 Score =  216 bits (544), Expect = 4e-55
 Identities = 132/370 (35%), Positives = 205/370 (54%), Gaps = 7/370 (1%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           + E I +LE+  A  P +K TE    ++K KLAE +++LE Q Q   GGG   AV++ G 
Sbjct: 3   LEEDIESLEEEIANTPYNKSTEAHIGRLKAKLAEQKEKLEAQ-QSGSGGGGGYAVEQHGD 61

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           A + LVG P+VGKS L+ A+T  D E   Y FTT    P M+ Y+   IQL++VPGLIEG
Sbjct: 62  ATVALVGFPSVGKSSLINAMTNADSEVGAYEFTTLNVNPGMLEYRGANIQLLDVPGLIEG 121

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           AA G+G G ++L+VIR AD +  V+   E  I+Q   L  E     I+V+   P + +RR
Sbjct: 122 AAGGRGGGKEILSVIRGADLVIFVLSAFE--IEQYDRLAEELYNVNIRVDAEPPSVTVRR 179

Query: 202 TPSGGIVINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAI 261
               GI +N    ++ D + V  +LRE    +A +T+R   +++   D + ++ V+  ++
Sbjct: 180 KGKDGIDVNTSGELELDSDTVKGILRERGFINANVTIRGNPSVDRLIDGVMDNRVYMPSL 239

Query: 262 IIANKGD--APGSKDNYEKLVKAYG-ERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFT 318
           +  NK D   P      +  ++ +G      I +SA +   LD +KE ++    +IR++ 
Sbjct: 240 VTVNKVDLIEPSYAGTMKDALRDHGVSPDDAIFISAAEEKGLDVLKERMWRALGLIRIYM 299

Query: 319 KSPGE-EPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377
             PG       P+ ++RG TV D  +++   L + FR+ARV G S +   Q+VG DHVLE
Sbjct: 300 DKPGRGVDREEPLIIRRGETVDDAVQKLGGTLDERFRFARVTGPSAQHDDQQVGRDHVLE 359

Query: 378 DGDIVEIHAR 387
           D D++ + AR
Sbjct: 360 DEDVLRVVAR 369


>gi|6321612 Ygr173wp [Saccharomyces cerevisiae]
           >gi|1723727|sp|P53295|YG3Y_YEAST HYPOTHETICAL 41.0 KD
           PROTEIN IN YIP1-CBP4 INTERGENIC REGION
           >gi|2120158|pir||S64487 GTP-binding protein DRG homolog
           - yeast (Saccharomyces cerevisiae)
           >gi|1323306|emb|CAA97199.1| (Z72958) ORF YGR173w
           [Saccharomyces cerevisiae]
           Length = 368
           
 Score =  214 bits (539), Expect = 1e-54
 Identities = 129/372 (34%), Positives = 210/372 (55%), Gaps = 12/372 (3%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYS-LAVKKEG 80
           I +KI+A+E+  A   K+K TE     +K KLA  R++L        GGG S   V K G
Sbjct: 3   IIDKIKAIEEEMARTQKNKATEHHLGLLKGKLARYRQQLLADEAGSGGGGGSGFEVAKSG 62

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140
            A++VL+G P+VGKS LL  +T    E A Y FTT   +P ++ Y+  +IQ+V++PG+I 
Sbjct: 63  DARVVLIGYPSVGKSSLLGKITTTKSEIAHYAFTTLTSVPGVLKYQGAEIQIVDLPGIIY 122

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIR 200
           GA+ GKG G Q++A  R AD + +V+D ++    Q   L +E E  GI++NK +P I  +
Sbjct: 123 GASQGKGRGRQVVATARTADLVLMVLDATKSE-HQRASLEKELENVGIRLNKEKPNIYYK 181

Query: 201 RTPSGGIVINGIENIKGDINE--VMKMLREEKIHSAEITVR-EPVTLEDFADALDES-LV 256
           +  +GG+ +      K ++ E  +  +LR+ +IH+AE+ VR +  T++DF D ++E    
Sbjct: 182 KKETGGVKVTFTSPPKTNLTEQAIKMILRDYRIHNAEVLVRDDQCTIDDFIDVINEQHRN 241

Query: 257 WKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRV 316
           + K + + NK DA  S +  +KL +        + +S +  + L  V E ++    + RV
Sbjct: 242 YVKCLYVYNKIDAV-SLEEVDKLAR----EPNTVVMSCEMDLGLQDVVEEIWYQLNLSRV 296

Query: 317 FTKSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375
           +TK  G  P +  P+ ++  ST+ D+   IH+D    F+YA VWG S K   Q+ G +H 
Sbjct: 297 YTKKRGVRPVFDDPLVVRNNSTIGDLCHGIHRDFKDKFKYALVWGSSAKHSPQKCGLNHR 356

Query: 376 LEDGDIVEIHAR 387
           ++D D+V + A+
Sbjct: 357 IDDEDVVSLFAK 368


>sp|P34280|YKK3_CAEEL HYPOTHETICAL 64.3 KD GTP-BINDING PROTEIN C02F5.3 IN CHROMOSOME III
           >gi|630509|pir||S44605 C02F5.3 protein - Caenorhabditis
           elegans >gi|289610|gb|AAA27918.1| (L14745) homology with
           GTP binding protein; putative [Caenorhabditis elegans]
           Length = 573
           
 Score =  213 bits (538), Expect = 2e-54
 Identities = 124/370 (33%), Positives = 206/370 (55%), Gaps = 10/370 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I EKI  +E   +   K+K TE     +K KLA+ R++L +   +    G    V K G 
Sbjct: 3   ILEKIAEIEHEISRTQKNKATEYHLGLLKAKLAKYRQQLLEPTGKGGAKGEGFDVMKSGD 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           A++ +VG P+VGKS LL ++T    E+A Y FTT   IP +++Y    IQL+++PG+IEG
Sbjct: 63  ARVAMVGFPSVGKSTLLSSMTSTHSEAAGYEFTTLTCIPGVISYNGANIQLLDLPGIIEG 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           A+ GKG G Q+++V + AD I +++D  +   +Q  +L RE E  GI++NK+ P I +++
Sbjct: 123 ASQGKGRGRQVISVAKTADLILMMLDAGKSD-QQKMLLERELEAVGIRLNKKPPNIYVKQ 181

Query: 202 TPSGGI-VINGIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
              GG+   N +     +   +M +L E KI +A++  RE  T+++F D +  + V+   
Sbjct: 182 KKVGGVKFTNTVPLTHCNEKLIMTVLHEYKIFNADVIFREDCTVDEFIDVIQGNRVYMTC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + NK D   S +  ++L +        + +S +  +N+D + E +++   ++RV+TK 
Sbjct: 242 LYVYNKVDQI-SIEEIDRLARMPHH----VVISCEMNLNMDYLLEKMWEYLALVRVYTKK 296

Query: 321 PGEEPAYPP---IALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLE 377
           PG  P   P   I L+ G+T+      +H+ +    RYA VWG S KF  QRVG  H L+
Sbjct: 297 PGNAPDLGPEDGIILRGGATIEHCCHALHRSIAAQLRYAIVWGTSTKFSPQRVGLHHKLD 356

Query: 378 DGDIVEIHAR 387
             D+++I  R
Sbjct: 357 HEDVIQIMRR 366


>gb|AAF77220.1|AC009601_14 (AC009601) L165.8 [Leishmania major]
           Length = 374
           
 Score =  204 bits (513), Expect = 2e-51
 Identities = 122/374 (32%), Positives = 211/374 (55%), Gaps = 18/374 (4%)

Query: 24  EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGG--GYSLAVKKEGA 81
           E+ +A+E+  A   K+K TE    ++K +LA ++ E+ +   +  G   G    V+K G 
Sbjct: 5   ERRKAIEEEIARTQKNKKTEYHVGRLKGQLARIKTEMMENAARAAGAKAGDGFDVRKSGD 64

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
            +  LVG P+VGKS  L  +T  + E+A Y FTT   IP  + +K  +IQ++++PG+IEG
Sbjct: 65  VRCALVGFPSVGKSSFLSCVTQTESEAAGYEFTTLTCIPGKLMHKGTEIQILDLPGIIEG 124

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
           AA GKG G Q++A  R AD I +++D ++   ++ KI   E E  GI++N+R P +  ++
Sbjct: 125 AAEGKGRGRQVIATARTADMIILMLDAAKAEAQRSKI-ESELESVGIRLNQRFPNVTFKK 183

Query: 202 TPSGGIVI----NGIENIKGDINEVMK-MLREEKIHSAEITVREPVTLEDFADALDESLV 256
             S  + +    + +   +G   +++K +L++  I +A++ +RE +T++ F D ++ +  
Sbjct: 184 KTSCSMNVVSYSSTVPQTRGVSEQMVKEVLKDYGIFNADVALREDITVDQFIDVIEGNRK 243

Query: 257 WKKAIIIANKGD--APGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEII 314
           +   + + NK D       D   +L  +       + +S    +N+D V + +++   II
Sbjct: 244 YMPCLYVYNKIDTITMEEMDRLSRLPHS-------VVLSLHWDLNVDEVIDEVWEHLNII 296

Query: 315 RVFTKSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPD 373
           R++TK  GE P +  P  +KR ++V  + +RIHKD+V  F+YA VWG S K   QRVG  
Sbjct: 297 RIYTKKHGEHPDFGKPFVVKRDASVEHICKRIHKDIVSRFKYALVWGTSAKHQPQRVGIS 356

Query: 374 HVLEDGDIVEIHAR 387
           H LED D+++I  R
Sbjct: 357 HELEDEDVLQIMLR 370


>sp|P32235|GTP1_SCHPO GTP-BINDING PROTEIN 1 >gi|419815|pir||JT0741 GTP-binding protein 1
           - fission yeast (Schizosaccharomyces pombe)
           >gi|173396|gb|AAA35308.1| (L00671) GTP-binding protein
           [Schizosaccharomyces pombe]
           Length = 364
           
 Score =  202 bits (509), Expect = 5e-51
 Identities = 124/364 (34%), Positives = 202/364 (55%), Gaps = 10/364 (2%)

Query: 24  EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83
           EKI+ +E       K+K TE     +K KLA+LR +L +   +    G    V K G A+
Sbjct: 5   EKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPTSKSGPKGEGFDVLKSGDAR 64

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           +  +G P+VGKS LL A+T     +A Y FTT   IP ++ Y   +IQ++++PG+IEGA+
Sbjct: 65  VAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVLEYDGAEIQMLDLPGIIEGAS 124

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSED-PIKQMKILLREFERAGIKVNKRRPRIEIRRT 202
            G+G G Q ++  R AD I +V    +  PI + KI   E E+ GI++N++ P + +   
Sbjct: 125 QGRG-GRQAVSAARTADLILMVFGCYKKLPISEKKIEY-ELEQVGIRLNRQPPNVTLTIK 182

Query: 203 PSGGIVIN-GIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAI 261
            +GGI  N  +     D      +L E +IH+A+I +RE +T++DF D +  +  +   +
Sbjct: 183 KNGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDITVDDFIDLVMGNRRYINCL 242

Query: 262 IIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSP 321
              +K DA  S +  ++L +      K + +S   ++NLD +KE +++   + R++TK  
Sbjct: 243 YCYSKIDAV-SLEEVDRLARLP----KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRK 297

Query: 322 GEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGD 380
           GE P +   + + +GST+  V  RIH+ L +  +YA VWG S K   Q VG +H +E+GD
Sbjct: 298 GEMPDFSEALIIHKGSTIEQVCNRIHRTLAEQLKYALVWGTSAKHSPQVVGLNHRVEEGD 357

Query: 381 IVEI 384
           +V I
Sbjct: 358 VVTI 361


>gi|11427872 developmentally regulated GTP-binding protein 2 [Homo sapiens]
           Length = 307
           
 Score =  198 bits (498), Expect = 1e-49
 Identities = 108/309 (34%), Positives = 176/309 (56%), Gaps = 8/309 (2%)

Query: 78  KEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPG 137
           K G A++ L+G P+VGKS  L  +T    E+A Y FTT   IP ++ YK   IQL+++PG
Sbjct: 2   KSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPG 61

Query: 138 LIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRI 197
           +IEGAA GKG G Q++AV R AD I +++D ++  + Q  +L +E E  GI++NK +P I
Sbjct: 62  IIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEV-QRSLLEKELESVGIRLNKHKPNI 120

Query: 198 EIRRTPSGGIVINGIENIKGDINEVMKM-LREEKIHSAEITVREPVTLEDFADALDESLV 256
             +    GGI  N    +     +++++ L E KI +AE+  RE  + ++F D +  + V
Sbjct: 121 YFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRV 180

Query: 257 WKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRV 316
           +   + + NK D    ++     V     +   + +S   ++NLD + E L++   +  +
Sbjct: 181 YMPCLYVYNKIDQISMEE-----VDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCI 235

Query: 317 FTKSPGEEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHV 375
           +TK  G+ P +   I L++G++V  V  RIH+ L   F+YA VWG S K+  QRVG  H 
Sbjct: 236 YTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHT 295

Query: 376 LEDGDIVEI 384
           +E  D+++I
Sbjct: 296 MEHEDVIQI 304


>pir||T06251 GTP binding protein - garden pea >gi|2345148|gb|AAB67829.1|
           (AF014821) developmentally regulated GTP binding protein
           [Pisum sativum]
           Length = 399
           
 Score =  194 bits (489), Expect = 1e-48
 Identities = 121/368 (32%), Positives = 194/368 (51%), Gaps = 11/368 (2%)

Query: 22  IPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGA 81
           I EKI+ +E   A   K+K TE    Q+K K+A+LR +L +  +   GGG    V K G 
Sbjct: 3   IIEKIKEIEFEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGSSGGGDGFEVTKFGH 62

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
            ++ L+G P+VGKS LL  LTG   E+A Y FTT   IP +     ++   +    L+  
Sbjct: 63  GRVALIGFPSVGKSTLLTLLTGTHSEAASYEFTTLTCIPGLYTTMILRFSCLIFLELLRV 122

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRR 201
               +  G Q++AV +++D + +V+D S+      +IL +E E  G+++NKR P+I  ++
Sbjct: 123 LLKARDCGRQVIAVAKSSDIVLMVLDASKSE-GHRQILTKELEAVGLRLNKRPPQIYFKK 181

Query: 202 TPSGGIVINGIENIKG-DINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKA 260
             +GGI  N    +   D     ++L E KIH+AEI  RE  T++DF D ++ +  + K 
Sbjct: 182 KKTGGISFNSTMPLTHVDEKLCYQILHEYKIHNAEILFREDATVDDFIDVIEGNRKYMKC 241

Query: 261 IIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKS 320
           + + N  D  G  D     V     +   + +S   ++NLD +   ++D   ++RV+TK 
Sbjct: 242 VYVYNLIDVVGIDD-----VDRLPRQPNSVVISCNLKLNLDRLLSRMWDEMGLVRVYTKP 296

Query: 321 PGEEPAY-PPIAL---KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVL 376
            G++P +  P+ L   + G +V D    IH+ LVK+ +Y  VWG   +   Q  G  HVL
Sbjct: 297 QGQQPDFSDPVVLSADRGGCSVEDFCNHIHRSLVKDVKYVLVWGIMARHYPQHCGLSHVL 356

Query: 377 EDGDIVEI 384
            D D+V+I
Sbjct: 357 RDEDVVQI 364


>emb|CAA19048.2| (AL023587) gtp-binding protein 1. [Schizosaccharomyces pombe]
           Length = 346
           
 Score =  190 bits (479), Expect = 2e-47
 Identities = 116/349 (33%), Positives = 194/349 (55%), Gaps = 9/349 (2%)

Query: 24  EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83
           EKI+ +E       K+K TE     +K KLA+LR +L +   +    G    V K G A+
Sbjct: 5   EKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPTSKSGPKGEGFDVLKSGDAR 64

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           +  +G P+VGKS LL A+T     +A Y FTT   IP ++ Y   +IQ++++PG+IEGA+
Sbjct: 65  VAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVLEYDGAEIQMLDLPGIIEGAS 124

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203
            G+G G Q ++  R AD I +V+D ++   ++ KI   E E+ GI++N++ P + +    
Sbjct: 125 QGRG-GRQAVSAARTADLILMVLDATKAADQREKIEY-ELEQVGIRLNRQPPNVTLTIKK 182

Query: 204 SGGIVIN-GIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262
           +GGI  N  +     D      +L E +IH+A+I +RE +T++DF D +  +  +   + 
Sbjct: 183 NGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDITVDDFIDLVMGNRRYINCLY 242

Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322
             +K DA  S +  ++L +      K + +S   ++NLD +KE +++   + R++TK  G
Sbjct: 243 CYSKIDAV-SLEEVDRLARLP----KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRKG 297

Query: 323 EEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRV 370
           E P +   + +++GST+  V  RIH+ L +  +YA VWG S K   Q V
Sbjct: 298 EMPDFSEALIVRKGSTIEQVCNRIHRTLAEQLKYALVWGTSAKHSPQVV 346


>pir||T40599 hypothetical protein SPBC649.06 - fission yeast
           (Schizosaccharomyces pombe) (fragment)
           Length = 347
           
 Score =  190 bits (479), Expect = 2e-47
 Identities = 116/349 (33%), Positives = 194/349 (55%), Gaps = 9/349 (2%)

Query: 24  EKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEGAAQ 83
           EKI+ +E       K+K TE     +K KLA+LR +L +   +    G    V K G A+
Sbjct: 5   EKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPTSKSGPKGEGFDVLKSGDAR 64

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEGAA 143
           +  +G P+VGKS LL A+T     +A Y FTT   IP ++ Y   +IQ++++PG+IEGA+
Sbjct: 65  VAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVLEYDGAEIQMLDLPGIIEGAS 124

Query: 144 LGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTP 203
            G+G G Q ++  R AD I +V+D ++   ++ KI   E E+ GI++N++ P + +    
Sbjct: 125 QGRG-GRQAVSAARTADLILMVLDATKAADQREKIEY-ELEQVGIRLNRQPPNVTLTIKK 182

Query: 204 SGGIVIN-GIENIKGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAII 262
           +GGI  N  +     D      +L E +IH+A+I +RE +T++DF D +  +  +   + 
Sbjct: 183 NGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDITVDDFIDLVMGNRRYINCLY 242

Query: 263 IANKGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPG 322
             +K DA  S +  ++L +      K + +S   ++NLD +KE +++   + R++TK  G
Sbjct: 243 CYSKIDAV-SLEEVDRLARLP----KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRKG 297

Query: 323 EEPAY-PPIALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRV 370
           E P +   + +++GST+  V  RIH+ L +  +YA VWG S K   Q V
Sbjct: 298 EMPDFSEALIVRKGSTIEQVCNRIHRTLAEQLKYALVWGTSAKHSPQVV 346


>gb|AAG01361.1|AC068666_8 (AC068666) L165.8 [Leishmania major]
           Length = 230
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 68/234 (29%), Positives = 129/234 (55%), Gaps = 16/234 (6%)

Query: 162 IAIVIDLSEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTPSGGIVI----NGIENIKG 217
           I +++D ++   ++ KI   E E  GI++N+R P +  ++  S  + +    + +   +G
Sbjct: 1   IILMLDAAKAEAQRSKIE-SELESVGIRLNQRFPNVTFKKKTSCSMNVVSYSSTVPQTRG 59

Query: 218 DINEVMK-MLREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSK--D 274
              +++K +L++  I +A++ +RE +T++ F D ++ +  +   + + NK D    +  D
Sbjct: 60  VSEQMVKEVLKDYGIFNADVALREDITVDQFIDVIEGNRKYMPCLYVYNKIDTITMEEMD 119

Query: 275 NYEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAY-PPIALK 333
              +L  +       + +S    +N+D V + +++   IIR++TK  GE P +  P  +K
Sbjct: 120 RLSRLPHS-------VVLSLHWDLNVDEVIDEVWEHLNIIRIYTKKHGEHPDFGKPFVVK 172

Query: 334 RGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHAR 387
           R ++V  + +RIHKD+V  F+YA VWG S K   QRVG  H LED D+++I  R
Sbjct: 173 RDASVEHICKRIHKDIVSRFKYALVWGTSAKHQPQRVGISHELEDEDVLQIMLR 226


>emb|CAA74319.1| (Y13986) GTP-binding protein [Ostertagia circumcincta]
           Length = 140
           
 Score =  104 bits (256), Expect = 2e-21
 Identities = 60/139 (43%), Positives = 82/139 (58%)

Query: 21  TIPEKIRALEKMYALVPKHKGTEKLRLQIKRKLAELRKELEKQRQQRKGGGYSLAVKKEG 80
           +I +KI+ +E   A   K+K T      +K K A+LR+EL   +    GGG    V K G
Sbjct: 2   SILQKIQDIEDEMARTQKNKATNAHLGMLKAKWAKLRQELIAPKGGGGGGGEGFDVAKTG 61

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIE 140
            A++  VG P+VGKS LL  L GV  E A Y FTT   +P ++ YK  +IQL+++PG+IE
Sbjct: 62  DARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIE 121

Query: 141 GAALGKGMGPQLLAVIRNA 159
           GA  GKG G Q++AV   A
Sbjct: 122 GAKDGKGRGKQVIAVALRA 140


>pir||G72586 hypothetical protein APE1164 - Aeropyrum pernix (strain K1)
           >gi|5104835|dbj|BAA80149.1| (AP000061) 410aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 410
           
 Score = 99.1 bits (243), Expect = 8e-20
 Identities = 114/418 (27%), Positives = 179/418 (42%), Gaps = 127/418 (30%)

Query: 80  GAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP-----------------IP-- 120
           G+  + LVG  NVGKS    A T V V+  + PF T EP                 +P  
Sbjct: 4   GSIVLGLVGKTNVGKSTFFAAATEVPVKIENRPFVTIEPNVGVGYARKRCAHVELGLPRC 63

Query: 121 ------AMMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL------ 168
                  +  ++ + ++L++V GL+ GA  G+G+G + L  +R ADA+ +V+D       
Sbjct: 64  DPVNSLCIEGWRFIPVKLLDVAGLVPGAHRGRGLGNRFLDDVRKADALLLVVDASGSTDP 123

Query: 169 --------SEDPIKQMKILLREFERAGIKVNKRRPRIEIRRTPSGGIV---------ING 211
                   S DP++++ ++L E     ++   R      RR  + G V         ++G
Sbjct: 124 EGVPVKPGSYDPVEEVGLMLGEIYEWMLQNLARDWERFARRVDTAGNVDLVTALSQRLSG 183

Query: 212 IENIKGDINEVMKM--LREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDA 269
            E  +G +  V++   L E+++ S     RE + L  F   + E    K A+I+ANK D 
Sbjct: 184 FEIPRGVVAGVLEETGLGEKRLSSWS---REDLRL--FVKLVLER--GKPAVILANKVDV 236

Query: 270 PGSKDNYEKLVKAYGERFKIIPVSAKKRINL----------------------------- 300
           PG+++N E+L  +Y     ++P SA   + L                             
Sbjct: 237 PGAEENVERLGSSY-PGIPVVPASALAELMLRRLAREGRVRYIPGDPDFTVKDPGGLGGK 295

Query: 301 ----------------------DAVKEALYDVAEIIRVFTKSPGEEP---------AYPP 329
                                  A+  A++DV ++I V+   P E+P           P 
Sbjct: 296 ALKALELVRERVMKRWGGTGVVQAINTAVFDVLDMIAVY---PVEDPNRYTDREGRILPD 352

Query: 330 IAL-KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHA 386
           + L KRGST  D+A RIH DL K F YA V  K+     QRVG  + L+DGD+V+I A
Sbjct: 353 VILVKRGSTPRDLAYRIHTDLGKTFLYA-VNAKT----KQRVGEGYRLQDGDVVKIVA 405


>pir||T42690 hypothetical protein DKFZp434N1827.1 - human (fragment)
           >gi|6453535|emb|CAB61403.1| (AL133085) hypothetical
           protein [Homo sapiens]
           Length = 150
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 56/152 (36%), Positives = 89/152 (57%), Gaps = 7/152 (4%)

Query: 235 EITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKAYGERFKIIPVSA 294
           ++T+R   T +D  D ++ + V+   I + NK D    + + E+L   Y      +P+SA
Sbjct: 1   DVTLRSDATADDLIDVVEGNRVYIPCIYVLNKID----QISIEELDIIYKVPH-CVPISA 55

Query: 295 KKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYP-PIALKRG-STVLDVAERIHKDLVKN 352
             R N D + E ++D  +++R++TK  G+ P Y  P+ L    +TV D   +IHK+L+K 
Sbjct: 56  HHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKE 115

Query: 353 FRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384
           F+YA VWG SVK   Q+VG DH LED D+++I
Sbjct: 116 FKYALVWGLSVKHNPQKVGKDHTLEDEDVIQI 147


>pir||C64466 GTP-binding protein - Methanococcus jannaschii
           >gi|1591973|gb|AAB99340.1| (U67573) GTP-binding protein,
           member of GTP1/OBG-family [Methanococcus jannaschii]
           Length = 393
           
 Score = 96.3 bits (236), Expect = 5e-19
 Identities = 103/402 (25%), Positives = 166/402 (40%), Gaps = 114/402 (28%)

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTT----------TEPIPA---------- 121
           A I LVG PNVGKS +  ALT    E  +YPFTT          T P P           
Sbjct: 2   AMIGLVGKPNVGKSTMFNALTEKPAEIGNYPFTTIQPNKGIAYITSPCPCKELGVKCNPR 61

Query: 122 ----MMNYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS-------- 169
               +   + + +++++V GL+ GA  G+GMG + L  +R ADA  +V+D S        
Sbjct: 62  NSKCIDGIRHIPVEVIDVAGLVPGAHEGRGMGNKFLDDLRQADAFILVVDASGKTDAEGN 121

Query: 170 ----EDPIKQMKILLREFERAGIKV-NKRRPRIEIRRTPSGGIV------INGIENIKGD 218
                DP++ +K LL E +     +  K   ++  R      IV      ++G+   + D
Sbjct: 122 PTENYDPVEDVKFLLNEIDMWIYSILTKNWDKLARRAQQEKNIVKALKDQLSGLNIDEDD 181

Query: 219 INEVMKMLREEKIHSAEITVREPVTLEDFAD-ALDESLVWKKAIIIANKGDAPGSKDNYE 277
           I   ++ + E  I   E         ED  + A     + K  II ANK D P ++ N E
Sbjct: 182 IKMAIRDMDESPIKWTE---------EDLLNLAKKLRKISKPMIIAANKADHPDAEKNIE 232

Query: 278 KLVKAYGERFKIIPVSAKKRINL------------------------------------- 300
           +L K + + + +IP SA+  + L                                     
Sbjct: 233 RLKKEFKD-YIVIPTSAEIELALKRAEKAGIIKRKENDFEIIDESKVNEQMRRAFDYIKD 291

Query: 301 -----------DAVKEALYDVAEIIRVF-----TKSPGEEPAYPPIA--LKRGSTVLDVA 342
                      + + +A +D+ ++I V+      K   ++    P A  +K+GST  D+A
Sbjct: 292 FLKKYGGTGVQECINKAYFDLLDMIVVYPVEDENKFSDKQGNVLPDAFLVKKGSTARDLA 351

Query: 343 ERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384
            ++H +L + F YA    K +     RVG D+ L+  DI++I
Sbjct: 352 YKVHTELGEKFIYAIDAKKKI-----RVGADYELKHNDIIKI 388


>pir||C75402 conserved hypothetical protein - Deinococcus radiodurans  (strain
           R1) >gi|6459140|gb|AAF10955.1|AE001984_5 (AE001984)
           conserved hypothetical protein [Deinococcus radiodurans]
           Length = 365
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 90/373 (24%), Positives = 156/373 (41%), Gaps = 88/373 (23%)

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ-------------- 129
           I +VGLPNVGKS L  A+T     +A+YPF T EP    +   D +              
Sbjct: 5   IGIVGLPNVGKSTLFNAITRAGALAANYPFATIEPNVGRVTVPDERLSALSQVFTKGERV 64

Query: 130 -------IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLRE 182
                  ++ V++ GL++GA+ G+G+G Q LA IR  DAIA V+   EDP          
Sbjct: 65  PPIIPTFVEFVDIAGLVKGASQGEGLGNQFLANIREVDAIAHVVRCFEDPNV-------- 116

Query: 183 FERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLR------EEKIHSAEI 236
                + V  R   ++   T +  +++  +  ++     + K  +      +E++  AE 
Sbjct: 117 -----VHVAGRVDPLDDIETINTELILADLAGLEKRAQNLQKKAKGGDKDAKEQLELAEQ 171

Query: 237 TVR-----EPVTLEDFADALDES---LVWKKAIIIANKGDAPGSKDN-YEKLVKAYG--E 285
            ++     +P     +   + +    +  K  I +AN G+   + DN Y + V+ Y   E
Sbjct: 172 IIQVLGEGKPARAGSYEGKIPKDFGLITIKPVIYVANVGEDDLTGDNEYVQKVREYAAAE 231

Query: 286 RFKIIPVSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGE 323
             +++ +SA+                      +   LD + +  Y+   +I   T    E
Sbjct: 232 GAQVVKISAQIEGELAEMPEDEAAAFLHDLGVEESGLDQLVKVGYETLGLITFITSGEKE 291

Query: 324 EPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPG----------QRVG 371
             A+    +++G    + A  IH DL + F  A V  W K V+  G          +  G
Sbjct: 292 VRAW---TIRKGEKAPEAAGEIHSDLERGFIRAEVIEWQKMVEAGGWAPAKAKGWVRTEG 348

Query: 372 PDHVLEDGDIVEI 384
            D+V++DGDI+ +
Sbjct: 349 KDYVMQDGDIMNV 361


>pir||H71165 probable GTP-binding protein - Pyrococcus horikoshii
           >gi|3256930|dbj|BAA29613.1| (AP000002) 397aa long
           hypothetical GTP-binding protein [Pyrococcus horikoshii]
           Length = 397
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 107/402 (26%), Positives = 169/402 (41%), Gaps = 111/402 (27%)

Query: 83  QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTE--------------------PIPAM 122
           +I +VG PNVGKS    A T VDVE A+YPFTT E                    P P  
Sbjct: 2   EIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTIEANVGVTYAITDHPCKELGCSPNPQN 61

Query: 123 MNYKD----VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS--------- 169
             Y++    + +++V+V GL+ GA  G+G+G + L  +R A A+  V+D +         
Sbjct: 62  YEYRNGLALIPVKMVDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVVDATGKTDPEGQP 121

Query: 170 ---EDPIKQMKILLREFERAGIKV-----NKRRPRIEIRRTPSGGIVINGIENIKGDINE 221
               DP++ ++ L RE +     +     +K   RI++++      +   +  I  + N+
Sbjct: 122 TDYHDPVEDIEFLEREIDYWIYGILSKGWDKFAKRIKLQKIKLESAIAEHLSGIGVNEND 181

Query: 222 VMKMLREEKIHSAEITVREPVTLED--FADALDESLVWKKAIIIANKGDAPGSKDNYEKL 279
           V      E +H   +        +D   A A +   V K  +I ANK DA  S +  ++L
Sbjct: 182 VW-----EAMHKLNLPEDPTKWSQDDLLAFASEIRRVNKPMVIAANKADA-ASDEQIKRL 235

Query: 280 VKAYGER-FKIIPVSA--------------------------------KKRINLDAVKEA 306
           V+   +R + +IP SA                                K++  L  +KE 
Sbjct: 236 VREEEKRGYIVIPTSAAAELTLRKAAKAGFIEYIPGASEFKVLRDMSEKQKRALMVIKEK 295

Query: 307 LYD------VAEII-RVFTKSPGEEPAYP-----------------PIALKRGSTVLDVA 342
           + D      V E+I RV        P YP                    +K+GST  D+A
Sbjct: 296 VLDRFGSTGVQEVINRVVFDLLKLIPVYPVHDENKLTDQFGNVLPHVFLMKKGSTPRDLA 355

Query: 343 ERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384
            ++H DL K F YA +  ++ +    RVG D+ L+  DIV+I
Sbjct: 356 FKVHTDLGKGFLYA-INARTKR----RVGEDYELQFNDIVKI 392


>pir||H75066 GTP-binding protein PAB1357 - Pyrococcus abyssi (strain Orsay)
           >gi|5458942|emb|CAB50429.1| (AJ248287) GTP-BINDING
           PROTEIN [Pyrococcus abyssi]
           Length = 397
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 101/402 (25%), Positives = 169/402 (41%), Gaps = 107/402 (26%)

Query: 83  QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTE--------------------PIPAM 122
           +I +VG PNVGKS    A T VDVE A+YPFTT +                    P P  
Sbjct: 2   EIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTIDANVGVTYAIAEHPCKELGCKPNPQN 61

Query: 123 MNYKD----VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL---------- 168
             Y++    + +++++V GL+ GA  G+G+G + L  +R A A+  V+D+          
Sbjct: 62  YEYREGLALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVVDVTGKTDAEGQP 121

Query: 169 --SEDPIKQMKILLREFERAGIKV-----NKRRPRIEIRRTPSGGIVINGIENIKGDINE 221
             + DPI+ ++ L RE +     +     +K   RI+++R      +   +  I    N+
Sbjct: 122 TENHDPIEDIEFLEREIDYWIYGILSKGWDKFAKRIKLQRIKLESAIAEHLSGIGVTEND 181

Query: 222 VMKMLREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVK 281
           V + +    + S + T+     L  FA  +    + K  II ANK DA  S++   +L+K
Sbjct: 182 VWEAMHRLGLPS-DPTLWSQEDLLAFASEIRR--INKPMIIAANKADA-ASEEQINRLIK 237

Query: 282 AYGER-FKIIPVSAKKRINL-------------------------DAVKEALYDVAEIIR 315
              +R + ++P SA   + L                         +  K+AL  + E + 
Sbjct: 238 EGEKRGYIVVPTSAAAELTLRKAAKAGFIDYIPGSSEFKILKDMNERQKKALLMIKEKVL 297

Query: 316 VFTKSPGEE--------------PAYP-----------------PIALKRGSTVLDVAER 344
               S G +              P YP                    +K+GS   D+A +
Sbjct: 298 DRFGSTGVQEVINKAVFELLNLIPVYPVQDENKLTDQFGNVLPHVFLMKKGSNPRDLAFK 357

Query: 345 IHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHA 386
           +H DL + F YA +  K+ +    R+G D+ L+  DI++I A
Sbjct: 358 VHTDLGRGFLYA-INAKTKR----RIGEDYELQFNDIIKIVA 394


>pir||E70354 probable GTP-binding protein - Aquifex aeolicus
           >gi|2983235|gb|AAC06832.1| (AE000698) hypothetical
           protein [Aquifex aeolicus]
           Length = 370
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 100/368 (27%), Positives = 168/368 (45%), Gaps = 81/368 (22%)

Query: 86  LVGLPNVGKSELLRALTG-VDVESADYPFTTTEP------IPAMMNYKDVQIQ------- 131
           +VGLPNVGKS L  ALT  +  ++A+YPF T EP      +P    YK  +I+       
Sbjct: 7   IVGLPNVGKSTLFNALTKTMKAQAANYPFCTIEPNVGVVEVPDERLYKLAEIEKSQKITP 66

Query: 132 ----LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIV-----------IDLSEDPIKQM 176
                V++ GL++GA+ G+G+G Q L+ IR  DA+A+V           ++ S DP++  
Sbjct: 67  TFIEFVDIAGLVKGASKGEGLGNQFLSHIREVDAVAMVLRAFEDENIVHVEGSVDPVRDK 126

Query: 177 KILLREFERAGIKVNKRRPRIE-IRRTPSGG--IVINGIENIKGDINEVMKMLREEKIHS 233
           +I+  E E     +     RIE +++   GG       +E++   + E+++ L   + ++
Sbjct: 127 EIV--EIELIAKDLESVNRRIEKVQKVAKGGDKKAREEMEHLNA-LKEILENLEPIRKYA 183

Query: 234 AEITVREPVTLEDFADALDESLVWKKAIIIAN--KGDAPGSKDN-YEKLVK--AYGERFK 288
            ++    P TLE +A      L  K  + IAN  + D P  + N + + +K  A  E   
Sbjct: 184 DKL---PPETLE-YAKKTLFLLTVKPVMYIANISEKDLPEGEGNPHVERIKEMANQENAP 239

Query: 289 IIPVSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPA 326
           ++ +SA+                      K   L+ V    Y + ++I  FT    E  A
Sbjct: 240 VVVISAELEAQLAGLSEEEQKEMLEAYGLKEPGLNKVIRTGYRLLDLITFFTAGEREARA 299

Query: 327 YPPIALKRGSTVLDVAERIHKDLVKNFRYARV-----------WGKSVKFPGQRV-GPDH 374
           +    +KRG+     A +IH D+ + F  A V           W K+ +    R+ G D+
Sbjct: 300 W---TVKRGTKAPQAAGKIHSDMERGFIAAEVISYEDLIKAGSWAKAKEQGLIRLEGKDY 356

Query: 375 VLEDGDIV 382
            ++DGD+V
Sbjct: 357 EIQDGDVV 364


>gb|AAF97355.1| (AY005820) Obg-like protein [Thermococcus zilligii]
           Length = 397
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 102/404 (25%), Positives = 166/404 (40%), Gaps = 111/404 (27%)

Query: 83  QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTE--------------------PIPAM 122
           ++ +VG PNVGKS    A T VDV+ A+YPFTT E                    P P  
Sbjct: 2   EVGVVGKPNVGKSTFFSAATLVDVDIANYPFTTIEANVGVTYAIADHPCKELGCRPNPQN 61

Query: 123 MNYKD----VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS--------- 169
             YKD    + +++++V GL+ GA  G+G+G + L  +R A A+  VID +         
Sbjct: 62  YEYKDGTALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVIDATGKTDAEGQP 121

Query: 170 ---EDPIKQMKILLREFERAGIKVNKR-----RPRIEIRRTPSGGIVINGIENIKGDINE 221
               DP++ ++ L RE +   + + K+       RI+++       + + +  I     +
Sbjct: 122 TDHHDPVEDIEFLEREIDYWMLGILKKGWEKFAKRIKLQHMKLEQAIADHLSGIGVKEED 181

Query: 222 VMKMLREEKIHSAEITVREPVTLEDFADALDESL--VWKKAIIIANKGDAPGSKDNYEKL 279
           V      E IH   +        +D   AL   L  + K  II ANK DA  S +  E+L
Sbjct: 182 VW-----EAIHRLGLGDDPTKWTDDELFALVRELRKINKPMIIAANKADA-ASDEQIERL 235

Query: 280 VKAYGER-FKIIPVSAKKRINL-------------------------------------- 300
            K   +R + +IP SA   + L                                      
Sbjct: 236 KKEGEKRGYLVIPTSAAAELTLRKAARAGFIDYIPGSSDFRILKEMNPQQEKALQLIKER 295

Query: 301 -----------DAVKEALYDVAEIIRVFTKSPGEE------PAYPPI-ALKRGSTVLDVA 342
                      + +  A++++ ++I V+      +         P +  L +GST  D+A
Sbjct: 296 VLERFGSTGVQEVINRAVFELLKLIPVYPVQDENKLTDQFGNVLPHVYLLPKGSTPRDLA 355

Query: 343 ERIHKDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEIHA 386
            ++H DL + F YA V  ++     +RVG D+ LE  DI++I A
Sbjct: 356 YKVHTDLGRTFLYA-VNART----HRRVGDDYKLEFNDIIKIVA 394


>dbj|BAB07770.1| (AP001520) GTP-binding protein [Bacillus halodurans]
           Length = 366
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 95/368 (25%), Positives = 155/368 (41%), Gaps = 85/368 (23%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQ-------------- 131
           +VGLPNVGKS L  A+T    ESA+YPF T +P   ++   D ++Q              
Sbjct: 7   IVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDPRLQKLTELVNPKKTVPT 66

Query: 132 ---LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL-----------SEDPIKQMK 177
                ++ G++EGA+ G+G+G Q L+ IR  DAI+ V+             S DPI+ + 
Sbjct: 67  AFEFTDIAGIVEGASKGEGLGNQFLSHIRQVDAISHVVRCFDDENITHVSGSVDPIRDIS 126

Query: 178 ILLREFERAGIK-VNKRRPRIE-IRRTPSGGIV--INGIENIKGDINEVMKMLREEKIHS 233
           ++  E   A ++ V+KR  R++ + +T     V  +  +E +K           E+   S
Sbjct: 127 VINLELILADLESVDKRFSRVQKLAKTKDKEAVAELEVLEKLKDAFE------NEKPARS 180

Query: 234 AEITVREPVTLEDFADALDESLVWKKAIIIAN--KGDAPGSKDN-YEKLVKAYG--ERFK 288
            E T  +   ++         L  K  + +AN  + D     DN + + VKA+   E  +
Sbjct: 181 IEFTEEQQKIVKGL-----HLLTSKPVLYVANVSEDDVLSPDDNPFVQKVKAFAAEENSE 235

Query: 289 IIPVSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPA 326
           +I VSAK                      +   LD +  A Y +  +   FT    E  A
Sbjct: 236 VIVVSAKIEEEIAELDGEEKAMFLEELGIQESGLDQLIRAAYSLLGLQTYFTAGEQEVRA 295

Query: 327 YPPIALKRGSTVLDVAERIHKDLVKNFRYAR-------VWGKSVKFPGQR-----VGPDH 374
           +     ++G+     A  IH D  K F  A        V   S+    +R      G ++
Sbjct: 296 W---TFRKGTKAPQAAGIIHSDFEKGFIRAETVSYNDLVEAGSMAVAKERGKVRLEGKEY 352

Query: 375 VLEDGDIV 382
           V++DGD++
Sbjct: 353 VVQDGDVI 360


>sp|P47270|Y024_MYCGE PROBABLE GTP-BINDING PROTEIN MG024 >gi|1361525|pir||F64202 probable
           GTP-binding protein - Mycoplasma genitalium
           >gi|3844633|gb|AAC71240.1| (U39681) GTP-binding protein,
           putative [Mycoplasma genitalium]
           Length = 367
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 88/358 (24%), Positives = 150/358 (41%), Gaps = 66/358 (18%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130
           +VGLPNVGKS L  A+T + VE A+YPF T EP   ++N  D ++               
Sbjct: 6   IVGLPNVGKSTLFSAITNLQVEIANYPFATIEPNTGIVNVSDERLDKLASLINPEKIVYT 65

Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177
             + V++ GL++GA+ G+G+G Q LA IR  D I  V+   +           DP+   +
Sbjct: 66  TFRFVDIAGLVKGASQGQGLGNQFLANIREVDLICHVVRCFQDKKIVHVNNTIDPVFDFE 125

Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGG-----------IVINGIENIKGDINEVMKML 226
           I++ E  +A  ++   R     R+  SG            IV+NG++  +  I + +   
Sbjct: 126 IIVNELIQADFELITNRIGKLKRKAESGDKIAKEEFVLLEIVLNGLKQGQMPI-QTLSES 184

Query: 227 REEKIHSAEITVREPVTL-----EDFADALDESLVWKKAIIIANKGDAPGSKDNYEKL-- 279
             + I S  +   +P+ +     E+    LD +   KK     ++   P +      +  
Sbjct: 185 ELKTIKSLNLLTAKPILIVANVSENDLLNLDNNEALKKLNAFLDQKKIPKAITVCSLIEK 244

Query: 280 ----VKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRG 335
               +K    ++ +  +  K    L+ V +A Y    +   FT    E  A+     K+G
Sbjct: 245 ELSGLKLEQRQYFLDELGLKNYSGLNRVIQAAYQTLNLWSFFTFGKKEVRAW---TFKKG 301

Query: 336 STVLDVAERIHKDLVKNFRYARV--WG--------KSVKFPG--QRVGPDHVLEDGDI 381
                 A +IH D  K F    V  W         +  K  G  +  G +++++DGD+
Sbjct: 302 WNAPQCAGQIHSDFEKGFIKVEVISWDQLFAMKSLQEAKKQGLIRLEGKNYLIKDGDV 359


>pir||B72418 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4980588|gb|AAD35192.1|AE001696_6 (AE001696)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 435
           
 Score = 82.7 bits (201), Expect = 6e-15
 Identities = 74/244 (30%), Positives = 120/244 (48%), Gaps = 30/244 (12%)

Query: 68  KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127
           KG    L ++ +  A + LVG PNVGKS L+  ++    + A+YPFTT  P   ++ Y D
Sbjct: 151 KGESRWLELELKILADVGLVGYPNVGKSSLISRISNARPKIANYPFTTLIPNLGVVKYDD 210

Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKILLREF 183
               + ++PGLIEGA+ G G+G   L  +     IA VID+S    EDP++   ++  E 
Sbjct: 211 FSFVVADIPGLIEGASEGVGLGNVFLRHVERCYLIAHVIDVSGYEREDPVRDYFVIREEM 270

Query: 184 ERAGIKVNKRRPRIEIRRTPSGGIVINGIENI-KGDINEVMKMLREEKIHSAEITVREPV 242
           ++        +P I         +V N I+ I K ++ +++K LR       + T RE +
Sbjct: 271 KKYS-PFLLEKPEI---------VVANKIDLIGKEELEKILKRLR-------DATNREVI 313

Query: 243 TLEDFADALDESLVWKKAIIIAN-KGDAPGSKDNYEKLVKAYGERFKIIPVSAKKRINLD 301
            +        + LV K A I+   K + P  K+  EK VK     ++ +P    ++ +L+
Sbjct: 314 PVSAVTGEGIDLLVSKLASIVREMKVEKPERKE--EKFVKP-SPVWRRLP----EKFHLE 366

Query: 302 AVKE 305
            VKE
Sbjct: 367 VVKE 370


>pir||G82870 GTP-binding protein UU595 [imported] - Ureaplasma urealyticum
           >gi|6899606|gb|AAF31009.1|AE002158_7 (AE002158)
           GTP-binding protein [Ureaplasma urealyticum]
           Length = 368
           
 Score = 82.3 bits (200), Expect = 8e-15
 Identities = 90/356 (25%), Positives = 151/356 (42%), Gaps = 63/356 (17%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130
           LVGLPNVGKS L   +T   VE+A+YPF T EP   ++N  D ++               
Sbjct: 7   LVGLPNVGKSTLFNTITNSRVEAANYPFATIEPNIGIVNINDPRLKRLASLVVPDKIVPT 66

Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177
             + V++ GL++GA+ G+G+G Q L  IR+ DAI  V+   +           D +  + 
Sbjct: 67  TFKFVDIAGLVKGASQGEGLGNQFLNNIRDVDAICHVVRCFDDKSITHVHNKIDALSDIH 126

Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGG-------IVINGIENI--KGDINEVMKMLRE 228
           ++  E   + + + ++R     ++  SG        +++  IE    KG +   +K+ +E
Sbjct: 127 VINYELILSDLDIIEKRISRIKKKADSGDKDARREYLILFNIEEALKKGQLASSVKLTKE 186

Query: 229 EK--IHSAEITVREPVTL-----EDFADALDESLVWKKAIIIANKGDAP----GSKDNYE 277
           E   I+S  +   +P+       E+     D +  + K    A   DA      +K  YE
Sbjct: 187 ELKIINSFNLITLKPILYIANISENEISNPDLNKEYLKVKKYAQDNDARCVALSAKIEYE 246

Query: 278 KLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRGST 337
             +     +   I     K   LD + +  YD+  +   FT    E  A+  I    G +
Sbjct: 247 ISILDEESKSIFIQDLGIKTTGLDEIVKQTYDLLNLKTYFTYGKQEVRAWTFI---NGMS 303

Query: 338 VLDVAERIHKDLVKNFRYARVW----------GKSVKFPG--QRVGPDHVLEDGDI 381
             + A  IH D  K F  A +            ++VK  G  +  G  ++++DGDI
Sbjct: 304 APECAGIIHSDFEKGFIKAEIMHYDDLISLGSEQAVKEAGKIRMEGKSYLMKDGDI 359


>pir||D70197 GTP-binding protein obg - Lyme disease spirochete
           >gi|2688719|gb|AAC67127.1| (AE001177) GTP-binding
           protein (obg) [Borrelia burgdorferi]
           Length = 328
           
 Score = 79.6 bits (193), Expect = 6e-14
 Identities = 50/128 (39%), Positives = 74/128 (57%), Gaps = 4/128 (3%)

Query: 71  GYSLAVKKEG--AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDV 128
           G SL+V+ E    A I LVGLPN GKS LL  +T      A+YPFTT  P   M+     
Sbjct: 148 GNSLSVRLELFLVADIGLVGLPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGMLRRSYD 207

Query: 129 QIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-DPIKQMKILLREFERAG 187
            + + ++PG+I+GA+ G G+G + L  I     +A+VID+SE + ++   ILL E +   
Sbjct: 208 DLIIADIPGIIKGASFGVGLGTKFLKHIAKTKILALVIDISEANFLESYNILLNELKSYS 267

Query: 188 IKV-NKRR 194
            K+ NK++
Sbjct: 268 HKLFNKKK 275


>pir||T40281 gtp-binding protein 1 - fission yeast (Schizosaccharomyces pombe)
           >gi|2950451|emb|CAA17801.1| (AL022071) gtp-binding
           protein 1 [Schizosaccharomyces pombe]
           Length = 135
           
 Score = 79.6 bits (193), Expect = 6e-14
 Identities = 37/98 (37%), Positives = 61/98 (61%), Gaps = 1/98 (1%)

Query: 288 KIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPP-IALKRGSTVLDVAERIH 346
           K + +S   ++NLD +KE +++   + R++TK  GE P +   + +++GST+  V  RIH
Sbjct: 35  KSVVISCNMKLNLDFLKERIWEELNLYRIYTKRKGEMPDFSEALIVRKGSTIEQVCNRIH 94

Query: 347 KDLVKNFRYARVWGKSVKFPGQRVGPDHVLEDGDIVEI 384
           + L +  +YA VWG S K   Q VG +H +E+GD+V I
Sbjct: 95  RTLAEQLKYALVWGTSAKHSPQVVGLNHRVEEGDVVTI 132


>pir||A64591 probable GTP-binding protein gtp1 - Helicobacter pylori  (strain
           26695) >gi|2313689|gb|AAD07637.1| (AE000571) GTP-binding
           protein (gtp1) [Helicobacter pylori 26695]
           Length = 366
           
 Score = 79.2 bits (192), Expect = 7e-14
 Identities = 94/369 (25%), Positives = 159/369 (42%), Gaps = 87/369 (23%)

Query: 86  LVGLPNVGKSELLRALTGV-DVESADYPFTTTEPIPAMMNYKDVQ--------------- 129
           +VGLPNVGKS    ALT   + +SA+YPF T EP  A++N  D +               
Sbjct: 7   IVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILH 66

Query: 130 --IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQM 176
             ++ V++ GLI+GA+ G+G+G Q LA I+  + I  V+   E           DP+  +
Sbjct: 67  SVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKIDPLNDI 126

Query: 177 KILLREFERAGI-KVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAE 235
           + +  E   A I  ++KR  R++             +++ K D   +++     K H  E
Sbjct: 127 ETIELELILADIAALDKRIDRLQ-----------KALKSSK-DAKNLLECALSLKTHLEE 174

Query: 236 ITVRE--PVTLEDFADALDESLVW---KKAIIIANKGDAP-GSKDNYEKLVK--AYGERF 287
           +   +  P+   +    LD+ L +   KK I +AN G+    + + + K VK  A  +  
Sbjct: 175 LKPAKTFPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNALNEHAKKVKNHAKEQNS 234

Query: 288 KIIPVSAKKRINL-----DAVKEALYDVA-----------------EIIRVFTKSPGEEP 325
           + + + AK    +     D VKE L  +                   +I  FT    E  
Sbjct: 235 EFVALCAKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVR 294

Query: 326 AYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPD 373
           ++    +K+GS+    A  IHKD  K F  A    +   + + G+            G D
Sbjct: 295 SW---TIKKGSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKD 351

Query: 374 HVLEDGDIV 382
           ++++DGD++
Sbjct: 352 YIVQDGDVL 360


>pir||A72280 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981794|gb|AAD36315.1|AE001779_17 (AE001779)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 357
           
 Score = 79.2 bits (192), Expect = 7e-14
 Identities = 87/372 (23%), Positives = 153/372 (40%), Gaps = 98/372 (26%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQL------------- 132
           +VGLPN GKS     LT   V +  +PF T EP   ++   D +I++             
Sbjct: 3   IVGLPNAGKSSFFNFLTDNSVPAESFPFCTIEPNVGILVVPDERIEILAKNEGSKKVVHP 62

Query: 133 ----VEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED----------------P 172
               V++ GL++GA+ G+G+G Q L  I   D IA V+ L ED                 
Sbjct: 63  FVEVVDIAGLVKGASKGEGLGNQFLDHISKVDVIAHVVRLFEDGRVSHPYQNVDPKRDIE 122

Query: 173 IKQMKILLREFERAGIKVNKRRPRIEIRRT--PSGGIVINGIENIKGDINEVMK------ 224
           I + +++L++ E    ++ K   R+++ RT        +  ++N++  +++  K      
Sbjct: 123 IVETELILKDLETVQKRLEK---RMKVARTGDKEAKREVELLQNLREFLSQGKKASKFPR 179

Query: 225 --MLREEKIHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVKA 282
                EE I S  +   +P  L    D LDE    K+ +I              E++VK 
Sbjct: 180 HDRFEEEVIESLFLLTDKPQILVFNVDELDEE---KRKLI--------------EEIVKE 222

Query: 283 YGERFKIIPVSAKKRINLDAVKEA--------------------LYDVAEIIRVFTKSPG 322
             E + II V  ++ +     +EA                    +  +  +IR  T +  
Sbjct: 223 KDEEYIIINVKLEEELKFLPEEEAEVFRREYNLFGDKRKEFFEKVLKLLNLIRFLTATQN 282

Query: 323 EEPAYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPG----------QRV 370
           E  ++    +K+GST  + A  IH D+ K F    V  + + V+F            +  
Sbjct: 283 EARSW---TIKKGSTAYEAAGLIHSDIQKGFIKVEVIPFERYVEFGSLKKAREAGAVETH 339

Query: 371 GPDHVLEDGDIV 382
           G D+++ +GD++
Sbjct: 340 GKDYIVREGDVI 351


>pir||B75563 GTP-binding protein Obg - Deinococcus radiodurans (strain R1)
           >gi|6457748|gb|AAF09676.1|AE001871_8 (AE001871)
           GTP-binding protein Obg [Deinococcus radiodurans]
           Length = 438
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 41/108 (37%), Positives = 64/108 (58%), Gaps = 7/108 (6%)

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ-------IQLVE 134
           A + LVG PN GKS LL AL+  +   ADYPFTT  PI  ++  +D Q         + +
Sbjct: 160 ADVGLVGYPNAGKSSLLAALSRANPAIADYPFTTLSPILGVVQREDEQGVSLDERFTMAD 219

Query: 135 VPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQMKILLRE 182
           +PG+IEGA+ GKG+G + L  I     +  V+D++ +P+++++ L  E
Sbjct: 220 IPGIIEGASEGKGLGLEFLRHISRTRLLVYVLDVTRNPVEELQQLQAE 267


>sp|P75088|Y024_MYCPN PROBABLE GTP-BINDING PROTEIN MG024 HOMOLOG (B01_ORF362)
           >gi|2146318|pir||S73454 probable GTP-binding protein
           yyaF - Mycoplasma pneumoniae  (strain ATCC 29342)
           >gi|1673787|gb|AAB95776.1| (AE000015) similar to GTPases
           [Mycoplasma pneumoniae]
           Length = 362
           
 Score = 78.4 bits (190), Expect = 1e-13
 Identities = 53/149 (35%), Positives = 79/149 (52%), Gaps = 30/149 (20%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130
           +VGLPNVGKS L  A+T + VE A+YPF T EP   ++N  D ++               
Sbjct: 6   IVGLPNVGKSTLFSAITNLQVEIANYPFATIEPNAGIVNVIDERLDKLASLIKPDKVTHT 65

Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177
             + V++ GL++GA+ G+G+G Q LA IR  D I  V+   E           DP+   +
Sbjct: 66  TFRFVDIAGLVKGASKGEGLGNQFLANIREVDLICHVVRCYEDKKIVHVNNQVDPVFDFE 125

Query: 178 ILLREFERAGIK-VNKRRPRIEIRRTPSG 205
           I++ E  +A I+ VN R  +I+ R+  SG
Sbjct: 126 IIVNELIQADIEVVNTRIGKIK-RKAESG 153


>pir||PC7024 hypothetical 218 protein - Acholeplasma laidlawii (fragment)
           Length = 218
           
 Score = 78.4 bits (190), Expect = 1e-13
 Identities = 50/144 (34%), Positives = 78/144 (53%), Gaps = 29/144 (20%)

Query: 84  IVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD---------------- 127
           I +VGLPNVGKS L  A+T   V +A+YPF T +P   +++ KD                
Sbjct: 4   IGIVGLPNVGKSTLFNAITKSQVTAANYPFATIDPNVGVVHVKDERLEKLAAIYKSGKII 63

Query: 128 -VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQ 175
              I+ +++ GL++GA+ G+G+G Q L+ IR  DAIA VI   E           DP++ 
Sbjct: 64  PTTIEFIDIAGLVKGASSGEGLGNQFLSHIRQVDAIAHVIRCFEDSEITHVEGKVDPLRD 123

Query: 176 MKILLREFERAGIK-VNKRRPRIE 198
           ++I+  E   + ++ V+KR  R+E
Sbjct: 124 LEIIEIELRLSDLESVDKRLARLE 147


>pir||E71920 hypothetical protein jhp0516 - Helicobacter pylori (strain J99)
           >gi|4155073|gb|AAD06109.1| (AE001485) putative
           [Helicobacter pylori J99]
           Length = 366
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 92/369 (24%), Positives = 158/369 (41%), Gaps = 87/369 (23%)

Query: 86  LVGLPNVGKSELLRALTGV-DVESADYPFTTTEPIPAMMNYKDVQ--------------- 129
           +VGLPNVGKS    ALT   + +SA+YPF T EP  A++N  D +               
Sbjct: 7   IVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILH 66

Query: 130 --IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQM 176
             ++ V++ GLI+GA+ G+G+G Q LA I+  + I  V+   E           DP+  +
Sbjct: 67  SVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKIDPLNDI 126

Query: 177 KILLREFERAGI-KVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAE 235
           + +  E   A I  ++KR  R++             +++ K D   +++     K H  E
Sbjct: 127 ETIELELILADIATLDKRIDRLQ-----------KALKSSK-DAKNLLECALSLKTHLEE 174

Query: 236 ITVRE--PVTLEDFADALDESLVW---KKAIIIANKGDAP-GSKDNYEKLVKAYG--ERF 287
           +   +  P+   +    LD+ L +   KK I +AN G+      + + K V+ +   +  
Sbjct: 175 LKPAKTFPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNILNEHAKKVENHAKVQNS 234

Query: 288 KIIPVSAKKRINL-----DAVKEALYDVA-----------------EIIRVFTKSPGEEP 325
           + + + AK    +     D VKE L  +                   +I  FT    E  
Sbjct: 235 EFVALCAKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVR 294

Query: 326 AYPPIALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPD 373
           ++    +K+GS+    A  IHKD  K F  A    +   + + G+            G D
Sbjct: 295 SW---TIKKGSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKD 351

Query: 374 HVLEDGDIV 382
           ++++DGD++
Sbjct: 352 YIVQDGDVL 360


>emb|CAC12034.1| (AL445065) GTP-binding protein Obg related protein [Thermoplasma
           acidophilum]
           Length = 382
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 43/121 (35%), Positives = 67/121 (54%), Gaps = 24/121 (19%)

Query: 81  AAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP---------------IPAMMNY 125
           + +I LVG PNVGKS    A T  + E  D+PFTT +P               I A  N 
Sbjct: 2   SVKIGLVGEPNVGKSTFFSAATQNEAEIGDFPFTTVKPNLGMTFFTVKCPDTEIGARCNP 61

Query: 126 KD---------VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSEDPIKQM 176
           ++         V +Q+++VPGLIEGA+ G+GMG + +  IR+ DAI +++D+S   + ++
Sbjct: 62  REGYCENGIRHVPVQVIDVPGLIEGASEGRGMGNEFMDAIRDVDAIVLIVDVSSGSVDEI 121

Query: 177 K 177
           +
Sbjct: 122 R 122


>pir||E70477 GTP-binding protein obg - Aquifex aeolicus
           >gi|2984292|gb|AAC07816.1| (AE000771) GTP-binding
           protein [Aquifex aeolicus]
           Length = 343
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 59/195 (30%), Positives = 97/195 (49%), Gaps = 22/195 (11%)

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYK-DVQIQLVEVPGLIE 140
           A + LVG PN GKS LL  LT    + ADYPFTT  P   +M    + ++ + ++PGLIE
Sbjct: 161 ADVGLVGFPNAGKSTLLSRLTRAKPKIADYPFTTLSPNLGVMELDWERRLVIADIPGLIE 220

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSE----DPIKQMKILLREFERAGIKVNKRRPR 196
            A  G G+G + L  I     +A VID+S+    +P++  + + RE E    K+  ++P+
Sbjct: 221 DAHKGAGLGHEFLRHIERTKFLAHVIDVSDFREREPVQAFEAINRELELYSPKL-AQKPQ 279

Query: 197 IEIRRTPSGGIVINGIENI--KGDINEVMKMLREEKIHSAEITVREPVTLEDFADALDES 254
           I         +V N I+ +  +  ++E+ K  +E+      ++      +E+  + L   
Sbjct: 280 I---------VVANKIDALSDRSLLSELEKYFKEKGYEFYAVSALTGEGIEELKEGL--- 327

Query: 255 LVWKKAIIIANKGDA 269
             WKK   I +K  A
Sbjct: 328 --WKKYEEIRDKESA 340


>pir||B82532 GTP-binding protein XF2641 [imported] - Xylella fastidiosa  (strain
           9a5c) >gi|9107872|gb|AAF85438.1|AE004071_6 (AE004071)
           GTP-binding protein [Xylella fastidiosa]
           Length = 363
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 92/363 (25%), Positives = 150/363 (40%), Gaps = 78/363 (21%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ---------------- 129
           +VGLPNVGKS L  ALT   + +A++PF T EP   ++   D +                
Sbjct: 7   IVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGVVPVPDPRLNQLAEIVKPQKLLPT 66

Query: 130 -IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177
            I+ V++ GL+ GAA G+G+G + LA IR  DAIA V+   E           DP+  ++
Sbjct: 67  VIEFVDIAGLVAGAASGEGLGNKFLAHIREVDAIAHVVRCFEHGQIIHVAGKVDPLADIE 126

Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEK-IHSAEI 236
           I+  E   A +   ++     +R    G       +++   +  +   L E K   SA +
Sbjct: 127 IIDTELILADLDTVEKACNRMMRAAKGGDKEAIACKSV---LERLQVALNEGKSARSAGL 183

Query: 237 TVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDN--YEKL-VKAYGERFKIIPVS 293
              E   + D        L  K  + IAN  +  G +DN   E L V+A  +  +++P+S
Sbjct: 184 DEDERALVRDLF-----LLTLKPVMYIANVLE-NGFQDNVYLEALRVRAASDNAQLVPIS 237

Query: 294 A----------------------KKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIA 331
           A                       +   L+ V  A Y +  +   FT    E  A+    
Sbjct: 238 AVIEEELAQLEDVDRDAFLVDLGLEEPGLNRVVRAAYALLGLQTYFTAGVKEVRAW---T 294

Query: 332 LKRGSTVLDVAERIHKDLVKNFRYAR--VWGKSVKFPGQR----------VGPDHVLEDG 379
           +K G+T    A  IH D  K F  A    +   +K+ G+            G ++ +++G
Sbjct: 295 VKSGATAPQAAAVIHTDFEKGFIRAETIAFDDFIKYKGEAGARDAGRMRLEGKEYRVQEG 354

Query: 380 DIV 382
           D++
Sbjct: 355 DVL 357


>pir||H81425 probable GTP-binding protein Cj0096 [imported] - Campylobacter
           jejuni (strain NCTC 11168) >gi|6967590|emb|CAB72580.1|
           (AL139074) putative GTP-binding protein [Campylobacter
           jejuni]
           Length = 350
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 52/164 (31%), Positives = 88/164 (52%), Gaps = 3/164 (1%)

Query: 68  KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127
           KG    + ++ +  A + LVG PNVGKS L+  ++    E A+Y FTT  P   +++  +
Sbjct: 145 KGESRLVRLELKLIADVGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVNE 204

Query: 128 V-QIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVID-LSEDPIKQMKILLR-EFE 184
                + ++PG+IEGA+ GKG+G   L  I     +  V+D + + P+K+  I+LR E E
Sbjct: 205 YNSFVMADIPGIIEGASGGKGLGLAFLKHIERTSFLLFVLDPMRQMPLKEQFIVLRKELE 264

Query: 185 RAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLRE 228
           +   ++  R+  I I ++ S  +     E I  +INE+   L+E
Sbjct: 265 KFSNELFGRKFGIMISKSDSVRLGEEFAEQIALNINELDNYLKE 308


>sp|P37518|YYAF_BACSU HYPOTHETICAL 40.1 KD GTP-BINDING PROTEIN IN RPSF-SPO0J INTERGENIC
           REGION >gi|2127015|pir||S66016 probable GTP-binding
           protein yyaF - Bacillus subtilis
           >gi|467376|dbj|BAA05222.1| (D26185) unknown [Bacillus
           subtilis] >gi|2636639|emb|CAB16129.1| (Z99124) similar
           to hypothetical proteins [Bacillus subtilis]
           Length = 366
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 87/365 (23%), Positives = 143/365 (38%), Gaps = 79/365 (21%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQ-------------- 131
           +VGLPNVGKS L  A+T    ESA+YPF T +P   ++   D ++Q              
Sbjct: 7   IVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLQKLTELVNPKKTVPT 66

Query: 132 ---LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL-----------SEDPIKQMK 177
                ++ G+++GA+ G+G+G + L+ IR  DAI  V+               DPI  ++
Sbjct: 67  AFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICHVVRAFSDDNITHVSGKVDPIDDIE 126

Query: 178 ILLREFERAGIK-VNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEI 236
            +  E   A ++ V KR  R+           +   E I   + E  +   E+   S E 
Sbjct: 127 TINLELILADMETVEKRITRVSKLAKQKDKDAVFEFE-ILSKLKEAFE--SEKPARSVEF 183

Query: 237 TVREPVTLEDFADALDESLVWKKAIIIANKGD----APGSKDNYEKLVK-AYGERFKIIP 291
           T  +   ++         L  K  + +AN  +     P   +N  K+ + A GE  ++I 
Sbjct: 184 TEEQQKLVKQL-----HLLTSKPILYVANVSEDEVADPSGNENVAKIREYAAGENAEVIV 238

Query: 292 VSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPP 329
           V AK                      +   LD + +A Y +  +   FT    E  A+  
Sbjct: 239 VCAKIESEIAELEGEEKQMFLEELGIQESGLDQLIKASYSLLGLATYFTAGEQEVRAW-- 296

Query: 330 IALKRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPG------------QRVGPDHVLE 377
              K+G    + A  IH D  + F  A          G            +  G ++V++
Sbjct: 297 -TFKKGMKAPECAGIIHSDFERGFIRAETVAYEDLLAGGGMAGAKEAGKVRLEGKEYVVQ 355

Query: 378 DGDIV 382
           DGD++
Sbjct: 356 DGDVI 360


>sp|P44681|YCHF_HAEIN PROBABLE GTP-BINDING PROTEIN HI0393 >gi|1074386|pir||I64150
           probable GTP-binding protein HI0393 - Haemophilus
           influenzae (strain Rd KW20) >gi|1573365|gb|AAC22052.1|
           (U32723) conserved hypothetical GTP-binding protein
           [Haemophilus influenzae Rd]
           Length = 363
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 89/365 (24%), Positives = 146/365 (39%), Gaps = 82/365 (22%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130
           +VGLPNVGKS L  ALT   +E+A+YPF T EP   ++   D ++               
Sbjct: 7   IVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNTGVVPMPDPRLDALAEIVKPERILPT 66

Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQMK 177
             + V++ GL+ GA+ G+G+G + LA IR  DAI  V+   E           DP+  + 
Sbjct: 67  TMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENDDIVHVAGKIDPLDDID 126

Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKML----REEKIHS 233
            +  E   A +   +R  +   +R   G       +  K +++ + K+L        I S
Sbjct: 127 TINTELALADLDSCERAIQRLQKRAKGGD------KEAKFELSVMEKILPVLENAGMIRS 180

Query: 234 AEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDNYEKLVK--AYGERFKIIP 291
             +   E   ++ +       L  K  + IAN  +     + Y   V+  A  E   ++P
Sbjct: 181 VGLDKEELQAIKSY-----NFLTLKPTMYIANVNEDGFENNPYLDRVREIAAKEGAVVVP 235

Query: 292 VSAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPP 329
           V A                       +   L+ V  A Y +  +   FT    E  A+  
Sbjct: 236 VCAAIESEIAELDDEEKVEFLQDLGIEEPGLNRVIRAGYALLNLQTYFTAGVKEVRAW-- 293

Query: 330 IALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPDHVLE 377
             +  G+T    A  IH D  K F  A V  +   ++F G+            G D++++
Sbjct: 294 -TVSVGATAPKAAAVIHTDFEKGFIRAEVIAYEDFIQFNGENGAKEAGKWRLEGKDYIVQ 352

Query: 378 DGDIV 382
           DGD++
Sbjct: 353 DGDVM 357


>pir||C70129 probable GTP-binding protein BB0235 - Lyme disease spirochete
           >gi|2688121|gb|AAC66614.1| (AE001133) conserved
           hypothetical protein [Borrelia burgdorferi]
           Length = 368
           
 Score = 73.7 bits (178), Expect = 3e-12
 Identities = 84/363 (23%), Positives = 147/363 (40%), Gaps = 73/363 (20%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130
           +VGLPNVGKS L  +LT  +VE A+YPF T EP   ++   D ++               
Sbjct: 7   IVGLPNVGKSTLFSSLTSSNVEIANYPFCTIEPNIGIVEIPDERLLKISECIIPRKIIPA 66

Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED-----------PIKQMK 177
             + V++ GL++GA+ G+G+G + LA IR    I  V+   E+           P K + 
Sbjct: 67  VMEFVDIAGLVKGASTGEGLGNKFLANIREVSLIVHVVRCFEEKEVIHINDDINPEKDIT 126

Query: 178 ILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAEIT 237
            +  E   + ++  ++  + + +   S        + I      ++ ML+  + H + + 
Sbjct: 127 TINVELCLSDLETVQKSLQKQEKNAKSTD------KKISESSKAIVLMLKRLEDHLSNMN 180

Query: 238 VREPVTLEDFADALDES---LVWKKAIIIANKGDAPGSKDNYEKLVK--AYGERFKIIPV 292
                  +DF      S   L +KK + + N  +   S + Y  +VK  A  E    + +
Sbjct: 181 PAVEFKFDDFEYNFIRSLNLLTFKKVLYVCNVDENSLSGNKYTDIVKNIALKEGNDFLIL 240

Query: 293 SAKKRINLDAVKEALYDVAEIIRVFTKSPGE-----EPAYPPIAL--------------- 332
            AK    L  +K+  Y   E++++F  +        + AY  + L               
Sbjct: 241 CAKIEAELAQIKDISYK-NEMLKLFGINDSGLGNLIKKAYYTLGLRTYFTAGLQEVRAWT 299

Query: 333 -KRGSTVLDVAERIHKDLVKNFRYARVWGKSVKFPGQRV------------GPDHVLEDG 379
            K+G      A  IH D  + F  A V+     F  Q V            G ++++ DG
Sbjct: 300 FKQGMRAPKAAGIIHSDFERGFIKAEVYSCEDLFKFQSVQKLKEKGLVRIEGKEYIVRDG 359

Query: 380 DIV 382
           D++
Sbjct: 360 DVI 362


>pir||S48582 hypothetical protein - Mycoplasma capricolum (SGC3) (fragment)
           >gi|7451193|pir||S77880 probable GTP-binding protein
           MC010 - Mycoplasma capricolum  (fragment)
           >gi|950066|emb|CAA83699.1| (Z33013) similar to GTP-bind.
           GTP1/OBG family [Mycoplasma capricolum]
           Length = 178
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 42/106 (39%), Positives = 58/106 (54%), Gaps = 17/106 (16%)

Query: 83  QIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ------------- 129
           Q+ +VGLPNVGKS L  A+T   VE+A+YPF T EP   ++   D +             
Sbjct: 4   QVGIVGLPNVGKSTLFNAITNSKVEAANYPFATIEPNVGIVEVPDYRLDELYKIFNSKKR 63

Query: 130 ----IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED 171
               I+ V++ GLI GA+ G+G+G   LA IR  DAI  V+   +D
Sbjct: 64  VATTIEFVDIAGLIAGASQGEGLGNAFLANIRQTDAICQVVRCFDD 109


>pir||T42036 obg protein - Streptomyces coelicolor >gi|1783290|dbj|BAA13498.1|
           (D87915) Obg [Streptomyces coelicolor A3(2)]
           >gi|6983737|emb|CAB75376.1| (AL139298) GTP-binding
           protein [Streptomyces coelicolor A3(2)]
           Length = 478
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 18/186 (9%)

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLVEVPGLIEG 141
           A + LVG P+ GKS L+  L+    + ADYPFTT  P   ++   +    + +VPGLI G
Sbjct: 160 ADVALVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGETVYTVADVPGLIPG 219

Query: 142 AALGKGMGPQLLAVIRNADAIAIVIDLS-----EDPIKQMKILLREFERAGIKVNKRRPR 196
           A+ GKG+G + L  +     +  V+D +      DP+  + ++  E    G   N  RPR
Sbjct: 220 ASQGKGLGLEFLRHVERCSVLVHVLDTATLESERDPLSDLDVIETELREYGGLDN--RPR 277

Query: 197 IEIRRTPSGGIVINGIENIKG-DINEVMKMLREEKIHSA-EITVREPVTLEDFADALDES 254
           I         +V+N I+   G D+ E+++   E + +   E++    + L + + AL E 
Sbjct: 278 I---------VVLNKIDVPDGKDLAEMVRPDLEARGYRVFEVSAVAHMGLRELSFALAEL 328

Query: 255 LVWKKA 260
           +   +A
Sbjct: 329 VATARA 334


>pir||S74797 GTP-binding protein obg - Synechocystis sp. (strain PCC 6803)
           >gi|1652022|dbj|BAA16948.1| (D90901) GTP-binding protein
           [Synechocystis sp.]
           Length = 368
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 45/140 (32%), Positives = 76/140 (54%), Gaps = 12/140 (8%)

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP-IPAMMNYKDVQIQLVEVPGLIE 140
           A++ ++GLPN GKS L+ AL+    + ADYPFTT  P +  +           ++PGLIE
Sbjct: 160 AEVGIIGLPNAGKSTLIAALSAARPKIADYPFTTLVPNLGVVRKPTGDGTVFADIPGLIE 219

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSE-DPIKQMKILLREFERAGIKVNKRRPRIEI 199
           GAA G G+G + L  I     +  V+D++  DPI   +++ +E +  G  + + +P+I  
Sbjct: 220 GAAAGIGLGHEFLRHIERTRLLLHVLDVTAGDPIANFRVIQQELDAYGRGITE-KPQI-- 276

Query: 200 RRTPSGGIVINGIENIKGDI 219
                  I +N I+ + G++
Sbjct: 277 -------IALNKIDALDGEM 289


>pir||T23645 hypothetical protein M01E5.2 - Caenorhabditis elegans
           >gi|3878629|emb|CAB07637.1| (Z93385) predicted using
           Genefinder~Similarity to B.subtilis GTP-binding protein
           (SW:P20964), contains similarity to Pfam domain: PF01018
           (GTP1/OBG family), Score=169.5, E-value=1e-49, N=1~cDNA
           EST yk457c2.5 comes from this gene [Caenorhabditis
           elegans]
           Length = 358
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 40/105 (38%), Positives = 61/105 (58%), Gaps = 5/105 (4%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDV-QIQLVEVPGLIEGAAL 144
           LVG PN GKS LLRA++    + A YPFTT  P   ++ Y+D  QI + ++PGLIE + L
Sbjct: 193 LVGFPNAGKSSLLRAISRAKPKVASYPFTTLHPHIGVVFYEDFEQIAVADIPGLIEDSHL 252

Query: 145 GKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKILLREFER 185
            KG+G   L  I   +++  V+D S     D  K +++ L  +++
Sbjct: 253 NKGLGISFLKHIERCESLWYVLDYSTGSLTDQYKMLRVELEGYQK 297


>pir||A81367 probable GTP-binding protein Cj0930 [imported] - Campylobacter
           jejuni (strain NCTC 11168) >gi|6968367|emb|CAB73187.1|
           (AL139076) putative GTP-binding protein [Campylobacter
           jejuni]
           Length = 367
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 85/364 (23%), Positives = 151/364 (41%), Gaps = 76/364 (20%)

Query: 86  LVGLPNVGKSELLRALTGV-DVESADYPFTTTEPIPAMMNYKDVQ--------------- 129
           +VGLPNVGKS    ALT   + +SA+YPF T EP  AM+   D++               
Sbjct: 7   IVGLPNVGKSTTFNALTKAQNAQSANYPFCTIEPNKAMVEVPDLRLNELAKIVKPERIMH 66

Query: 130 --IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-----------DPIKQM 176
             I+ V++ GL++GA+ G+G+G + L+ IR  + I  ++   +           DP++ +
Sbjct: 67  SLIEFVDIAGLVKGASKGEGLGNKFLSNIRETEVILHIVRCFDEENITHVEGGVDPLRDV 126

Query: 177 KILLREFERAGI-KVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEKIHSAE 235
           +I+  E   A I +++K+  ++      +       +E     ++ + K L        E
Sbjct: 127 EIINTELILADIEQLSKKIEKLTKEAKANQKGAKESLELANSLLDHLNKGLAASSYPEKE 186

Query: 236 ITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSKDN-YEKLVKAYGER--FKIIPV 292
             + + +  E         L  K+ I  AN  +   S+DN Y K +K Y ++   ++I +
Sbjct: 187 SEIYQALIKE------LRLLSAKEVIYGANVDENGISEDNDYVKALKEYAKKNDHEVIKL 240

Query: 293 SAK----------------------KRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPI 330
            AK                          LD +    +    +I  FT    E  ++   
Sbjct: 241 CAKIEEELVGLSDEESHEFLSSLGVNESGLDQIIRTAFAKLGLISYFTAGVVEVRSW--- 297

Query: 331 ALKRGSTVLDVAERIHKDLVKNFRYARV--WGKSVKFPGQR----------VGPDHVLED 378
            +K+G      A  IH D  K F  A V  +   +++ G+            G D+++ D
Sbjct: 298 TIKKGWKAPKAASVIHNDFEKGFIKAEVISYEDYIQYKGENGAKEAGKLRLEGKDYIVLD 357

Query: 379 GDIV 382
           GD++
Sbjct: 358 GDVM 361


>gb|AAF75096.1|AC007583_32 (AC007583) It is a member of GTP1/OBG family PF|01018. [Arabidopsis
           thaliana]
           Length = 1029
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 41/119 (34%), Positives = 62/119 (51%), Gaps = 8/119 (6%)

Query: 74  LAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLV 133
           L ++ +  A + LVG+PN GKS LL AL+        Y FTT  P    +NY D  + + 
Sbjct: 832 LILELKSIADVGLVGMPNAGKSTLLGALSRAKPRVGHYAFTTLRPNLGNVNYDDFSMTVA 891

Query: 134 EVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE--------DPIKQMKILLREFE 184
           ++PGLI+GA   +G+G   L  I     +A V+DL+          P +Q++ L+ E E
Sbjct: 892 DIPGLIKGAHQNRGLGHNFLRHIERTKVLAYVVDLASGLDGCEGLTPWQQLRDLVMELE 950


>gb|AAF79543.1|AC022464_1 (AC022464) F22G5.1 [Arabidopsis thaliana]
           Length = 445
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 41/119 (34%), Positives = 62/119 (51%), Gaps = 8/119 (6%)

Query: 74  LAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQIQLV 133
           L ++ +  A + LVG+PN GKS LL AL+        Y FTT  P    +NY D  + + 
Sbjct: 248 LILELKSIADVGLVGMPNAGKSTLLGALSRAKPRVGHYAFTTLRPNLGNVNYDDFSMTVA 307

Query: 134 EVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE--------DPIKQMKILLREFE 184
           ++PGLI+GA   +G+G   L  I     +A V+DL+          P +Q++ L+ E E
Sbjct: 308 DIPGLIKGAHQNRGLGHNFLRHIERTKVLAYVVDLASGLDGCEGLTPWQQLRDLVMELE 366


>dbj|BAA13501.1| (D87916) Obg [Streptomyces griseus]
           Length = 478
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 42/134 (31%), Positives = 66/134 (48%), Gaps = 7/134 (5%)

Query: 69  GGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDV 128
           G    + ++ +  A + LVG P+ GKS L+  L+    + ADYPFTT  P   ++     
Sbjct: 147 GESRDIVLELKTVADVALVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGST 206

Query: 129 QIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS-----EDPIKQMKILLREF 183
              + +VPGLI GA+ GKG+G + L  +     +  V+D +      DP+  + ++  E 
Sbjct: 207 VYTIADVPGLIPGASQGKGLGLEFLRHVERCSVLVHVLDTATLESDRDPVSDLDMIEEEL 266

Query: 184 ERAGIKVNKRRPRI 197
              G   N  RPRI
Sbjct: 267 RLYGGLEN--RPRI 278


>pir||D81037 GTP-binding protein, probable NMB1838 [imported] - Neisseria
           meningitidis (group B strain MD58, group A strain Z2491)
           >gi|7227093|gb|AAF42173.1| (AE002533) GTP-binding
           protein, putative [Neisseria meningitidis MC58]
           >gi|7379353|emb|CAB83908.1| (AL162753) hypothetical
           protein NMA0618 [Neisseria meningitidis Z2491]
           Length = 363
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 40/103 (38%), Positives = 57/103 (54%), Gaps = 17/103 (16%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQ---------------- 129
           +VGLPNVGKS L  ALT   +E+A+YPF T EP   ++   D +                
Sbjct: 7   IVGLPNVGKSTLFNALTQSGIEAANYPFCTIEPNVGIVEVPDPRMAELAKIVNPQKMQPA 66

Query: 130 -IQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED 171
            ++ V++ GL+ GA+ G+G+G Q LA IR  DAI  V+   +D
Sbjct: 67  IVEFVDIAGLVAGASKGEGLGNQFLANIRETDAIVNVVRCFDD 109


>pir||F71665 hypothetical protein RP604 - Rickettsia prowazekii
           >gi|3861148|emb|CAA15048.1| (AJ235272) unknown
           [Rickettsia prowazekii]
           Length = 365
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 85/359 (23%), Positives = 150/359 (41%), Gaps = 68/359 (18%)

Query: 86  LVGLPNVGKSELLRALTGVDV-ESADYPFTTTEPIPAMMNYKDVQIQ------------- 131
           +VGLPNVGKS L  ALT   + ++A+YPF T EP  + +   D ++Q             
Sbjct: 7   IVGLPNVGKSTLFNALTASQIADAANYPFCTIEPNSSKVLVPDERLQRLVSLVGSNKMIP 66

Query: 132 ----LVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSED-----------PIKQM 176
                V++ GL++GA+ G G+G + L+ IR  DAI  V+   ED           P+  +
Sbjct: 67  SYIEFVDIAGLVKGASKGDGLGNKFLSHIREVDAILHVLRCFEDEDIMHVHNKIDPLYDI 126

Query: 177 KILLREFERAGIKVNKRRPRIEIRRTPSGGIVINGIENIKGDINEVMKMLREEK------ 230
           +++  E     I   ++      +R  SG   +  +E I   + E+ K+L E K      
Sbjct: 127 EVIETELILTDIASLEKHFIKSEKRLKSGDKKM--VEQI-ALLKEIYKVLAEGKPARILN 183

Query: 231 -------IHSAEITVREPVTLEDFADALDESLVWKKAIIIANKGDAPGSK--------DN 275
                  +   ++   +P+         D ++  K   ++A + +   +K        ++
Sbjct: 184 EVLGADNLKQLQLITSKPILYVCNVFEQDAAIGNKFTQLVAKRAETEKTKSLVISSKIES 243

Query: 276 YEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRG 335
              L+++  E+ + +      +  L  V +  Y++  +   FT  P E  ++     K G
Sbjct: 244 EIALLESVEEKEEFLKYIGLNKTGLSKVIKEGYNLLNLKSFFTIGPKEAHSW---TFKDG 300

Query: 336 STVLDVAERIHKDLVKNFRYARVWG-----------KSVKFPGQRV-GPDHVLEDGDIV 382
           +     A  IH D  K F  A V             K+ +    R+ G D+ ++DGDIV
Sbjct: 301 TLAPAAAGIIHTDFEKGFIRAEVISYEDYINLGSEAKAKEVGKMRLEGKDYKMQDGDIV 359


>dbj|BAA91783.1| (AK001603) unnamed protein product [Homo sapiens]
           Length = 401
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 41/113 (36%), Positives = 64/113 (56%), Gaps = 2/113 (1%)

Query: 74  LAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYK-DVQIQL 132
           L ++ +  A   +VG PN GKS LLRA++      A YPFTT +P   +++Y+  +QI +
Sbjct: 217 LHLELKTVAHAGMVGFPNAGKSSLLRAISNARPAVASYPFTTLKPHVGIVHYEGHLQIAV 276

Query: 133 VEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLSE-DPIKQMKILLREFE 184
            ++PG+I GA   +G+G   L  I     +  V+DLS+ +P  Q+  L  E E
Sbjct: 277 ADIPGIIRGAHQNRGLGSAFLRHIERCRFLLFVVDLSQPEPWTQVDDLKYELE 329


>dbj|BAB13092.1| (AP001119) hypothetical 43.3 kD GTP-binding protein in dacB-rpmA
           intergenic region (F390) [Buchnera sp. APS]
           Length = 334
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 39/119 (32%), Positives = 68/119 (56%), Gaps = 6/119 (5%)

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMN-YKDVQIQLVEVPGLIE 140
           A +  +G+PNVGKS L+  ++G   + +DYPFTT  P+   +N  K+ +  + ++PG+I+
Sbjct: 160 ADVGTLGMPNVGKSTLVTNISGAKTKISDYPFTTLHPVLGSVNIQKNKKFIIADIPGIIK 219

Query: 141 GAALGKGMGPQLLAVIRNADAIAIVIDLSED----PIKQMKILLREFERAGIKV-NKRR 194
           GA+ G G+G + L  +     +  +IDL       P   +K +L E ++  +K+ NK R
Sbjct: 220 GASYGAGLGIRFLKHLERCKLLLHIIDLVPQNNCHPSDNIKTVLNELKKYSLKLYNKPR 278


>sp|P42641|YHBZ_ECOLI HYPOTHETICAL 43.3 KD GTP-BINDING PROTEIN IN DACB-RPMA INTERGENIC
           REGION >gi|7428736|pir||A65109 GTP-binding protein obg -
           Escherichia coli (strain K-12) >gi|606121|gb|AAA57984.1|
           (U18997) ORF_f390 [Escherichia coli]
           >gi|1789574|gb|AAC76215.1| (AE000399) putative
           GTP-binding factor [Escherichia coli K12]
           Length = 390
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 39/111 (35%), Positives = 63/111 (56%), Gaps = 9/111 (8%)

Query: 82  AQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP---IPAMMNYKDVQIQLVEVPGL 138
           A + ++G+PN GKS  +RA++    + ADYPFTT  P   +  M N K   +   ++PGL
Sbjct: 160 ADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVV--ADIPGL 217

Query: 139 IEGAALGKGMGPQLLAVIRNADAIAIVIDL----SEDPIKQMKILLREFER 185
           IEGAA G G+G + L  +     +  +ID+      DP++  +I++ E E+
Sbjct: 218 IEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEK 268


>pir||H83074 GTP-binding protein Obg PA4566 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9950812|gb|AAG07954.1|AE004870_5
           (AE004870) GTP-binding protein Obg [Pseudomonas
           aeruginosa]
           Length = 406
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 42/134 (31%), Positives = 72/134 (53%), Gaps = 9/134 (6%)

Query: 67  RKGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEP---IPAMM 123
           + G    L ++ +  A + L+GLPN GKS  +RA++    + ADYPFTT  P   + ++ 
Sbjct: 145 KPGEARDLKLELKVLADVGLLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPNLGVVSVG 204

Query: 124 NYKDVQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKIL 179
            YK   +   ++PGLIEGAA G G+G + L  +     +  ++D++     DP    +++
Sbjct: 205 RYKSFVV--ADIPGLIEGAAEGAGLGIRFLKHLARTRILLHLVDMAPLDESDPADAAEVI 262

Query: 180 LREFERAGIKVNKR 193
           +RE  R    + +R
Sbjct: 263 VRELGRFSPALTER 276


>pir||T30310 probable GTP binding protein - Lactococcus lactis (fragment)
           >gi|2909718|gb|AAC12968.1| (U76424) putative GTP binding
           protein [Lactococcus lactis]
           Length = 214
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 49/151 (32%), Positives = 75/151 (49%), Gaps = 34/151 (22%)

Query: 86  LVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKDVQI--------------- 130
           +VGLPNVGKS L  A+T    E+A+YPF T +P   M+   D ++               
Sbjct: 7   IVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLNKLTELIKPKKTVPT 66

Query: 131 --QLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVI---------------DLSEDPI 173
             +  ++ G+++GA+ G+G+G + LA IR  DAI  V+               D   DP+
Sbjct: 67  TFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIIHVVRAFDDENVMRENNREDAFIDPM 126

Query: 174 KQMKILLREFERAGIK-VNKRRPRIE-IRRT 202
             ++ +  E   A ++ VNKR  R+E I RT
Sbjct: 127 ADIETINLELILADLESVNKRYARVEKIART 157


>pir||S75088 probable GTP-binding protein sll0245 - Synechocystis sp.  (strain
           PCC 6803) >gi|1653033|dbj|BAA17950.1| (D90910)
           hypothetical protein [Synechocystis sp.]
           Length = 363
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 90/359 (25%), Positives = 149/359 (41%), Gaps = 69/359 (19%)

Query: 86  LVGLPNVGKSELLRALTG-VDVESADYPFTTTEPIPAMMNYKD----------------- 127
           +VGLPNVGKS L  AL      E+A++PF T EP   +++  D                 
Sbjct: 6   IVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVSVPDDRLGKLAEISQSVKVVP 65

Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDL-----------SEDPIKQM 176
            +++ V++ GL+ GA+ G+G+G Q LA IR  DAI  V+             S DP++ +
Sbjct: 66  TRMEFVDIAGLVAGASKGEGLGNQFLANIREVDAIVHVVRCFDDDDIIHVSGSVDPVRDV 125

Query: 177 KILLREFERAGI-KVNKR--RPRIEIRRTPSGGIVINGIENIKGDINEVMKMLR------ 227
           +++  E   A + +V KR  R R + R        +  +E +   +NE +   R      
Sbjct: 126 EVIDLELVLADLAQVEKRLERSRKQARGNKDLLEEVAILERLVAALNEGIPARRVGLTAE 185

Query: 228 -EEKIHSAEITVREP------VTLEDFADALDESLVWKKAI-IIANKGDAP----GSKDN 275
            +E I S  +   +P      VT +D A   D    W + +  IA K +A      ++  
Sbjct: 186 EQELIKSLGLLTLKPIIYATNVTEDDLAGGND----WVEQVKAIAAKDEAKVVVISAQVE 241

Query: 276 YEKLVKAYGERFKIIPVSAKKRINLDAVKEALYDVAEIIRVFTKSPGEEPAYPPIALKRG 335
            E +     ER   +         L ++  A Y++  +    T  P E  A+  I+   G
Sbjct: 242 SELVELPEEERQDFLASLGVTEGGLKSLIRATYELLGLRTYLTTGPQETRAWTIIS---G 298

Query: 336 STVLDVAERIHKDLVKNFRYAR------------VWGKSVKFPGQRVGPDHVLEDGDIV 382
                 A  IH D  + F  A             + G   K   +  G ++V+++GD++
Sbjct: 299 MKAPQAAGVIHTDFERGFIRAETVAYEDLISCGSMQGAKEKGLVRSEGKEYVVQEGDVL 357


>sp|P75215|Y384_MYCPN PROBABLE GTP-BINDING PROTEIN MG384 HOMOLOG >gi|2146144|pir||S73605
           GTP-binding protein obg - Mycoplasma pneumoniae (strain
           ATCC 29342) >gi|1673950|gb|AAB95927.1| (AE000027) small
           GTPase OBG involved in cell growth [Mycoplasma
           pneumoniae]
           Length = 433
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 38/139 (27%), Positives = 72/139 (51%), Gaps = 4/139 (2%)

Query: 68  KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127
           KG    ++++ +  A + +VG PN GKS L+  L+    + A+Y FTT  P+  ++ + D
Sbjct: 146 KGQSLHVSLEIKYLANVGIVGFPNTGKSTLISKLSNAKPKIANYRFTTLVPVLGVVKHND 205

Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS----EDPIKQMKILLREF 183
             +   ++PGLIE A+ G G+G   L  I   + +  +I L     +DP +  + ++RE 
Sbjct: 206 QSLVFADIPGLIENASEGSGLGHYFLRHIERCEILIHLISLDPVDHDDPCQAYEQIMREL 265

Query: 184 ERAGIKVNKRRPRIEIRRT 202
            +    + K++  +   +T
Sbjct: 266 SKYSQLLVKKKMLVVANKT 284


>pir||F70680 probable obg - Mycobacterium tuberculosis (strain H37RV)
           >gi|1666144|emb|CAB03779.1| (Z81451) obg [Mycobacterium
           tuberculosis]
           Length = 479
           
 Score = 69.1 bits (166), Expect = 8e-11
 Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 5/120 (4%)

Query: 68  KGGGYSLAVKKEGAAQIVLVGLPNVGKSELLRALTGVDVESADYPFTTTEPIPAMMNYKD 127
           KG    L ++ +  A + LVG P+ GKS L+ A++    + ADYPFTT  P   +++  +
Sbjct: 146 KGQSRDLTLELKTVADVGLVGFPSAGKSSLVSAISAAKPKIADYPFTTLVPNLGVVSAGE 205

Query: 128 VQIQLVEVPGLIEGAALGKGMGPQLLAVIRNADAIAIVIDLS-----EDPIKQMKILLRE 182
               + +VPGLI GA+ G+G+G   L  I     +  V+D +      DPI  +  L  E
Sbjct: 206 HAFTVADVPGLIPGASRGRGLGLDFLRHIERCAVLVHVVDCATAEPGRDPISDIDALETE 265


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.316    0.137    0.378 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 139656698
Number of Sequences: 2977
Number of extensions: 5816384
Number of successful extensions: 22383
Number of sequences better than 1.0e-10: 85
Number of HSP's better than  0.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 22113
Number of HSP's gapped (non-prelim): 102
length of query: 387
length of database: 189,106,746
effective HSP length: 59
effective length of query: 328
effective length of database: 153,796,013
effective search space: 50445092264
effective search space used: 50445092264
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)