BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2043 (trpC) DE:INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (EC
4.1.1.48) (IGPS).
(229 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75163 indole-3-glycerol-phosphate synthase (EC 4.1.1.48) P... 453 e-127
sp|Q9YGB5|TRPC_PYRKO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 354 4e-97
gi|11499197 anthranilate synthase component II (trpD) [Archaeogl... 192 2e-48
sp|Q58328|TRPC_METJA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 168 5e-41
sp|O67657|TRPC_AQUAE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 150 2e-35
sp|P18304|TRPC_HALVO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 140 2e-32
sp|Q01999|TRPC_LACLA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 133 2e-30
dbj|BAB05380.1| (AP001512) indol-3-glycerol phosphate synthase [... 131 1e-29
pir||E81395 indole-3-glycerol phosphate synthase (EC 4.1.1.48) C... 129 3e-29
sp|Q06121|TRPC_SULSO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 129 4e-29
gb|AAK41177.1| Indole-3-glycerol phosphate synthase (trpC) [Sulf... 129 4e-29
pir||S50179 indole-3-glycerol-phosphate synthase - Sulfolobus so... 129 4e-29
pdb|1A53| Complex Of Indole-3-Glycerolphosphate Synthase From ... 129 4e-29
pir||H75396 indole-3-glycerol phosphate synthase - Deinococcus r... 126 2e-28
sp|P17217|TRPC_LACCA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 125 6e-28
sp|P26939|TRPC_METTM INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 124 1e-27
gb|AAG18886.1| (AE004991) indole-3-glycerol-phosphate synthase; ... 121 6e-27
emb|CAB60751.1| (Y18640) indole-3-glycerol phosphate synthase [S... 121 8e-27
sp|O27694|TRPC_METTH INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 121 8e-27
sp|P70937|TRPC_BACME INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 117 1e-25
sp|P20578|TRPC_PSEPU INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 117 1e-25
sp|O68814|TRC1_STRCO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE 1 (IGP... 117 1e-25
gb|AAD35233.1|AE001699_10 (AE001699) indole-3-glycerol phosphate... 117 1e-25
pir||T35068 indole-3-glycerol-phosphate synthase - Streptomyces ... 117 1e-25
sp|Q56319|TRPC_THEMA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) 117 1e-25
pir||S59047 indole-3-glycerol phosphate synthase - Thermotoga ma... 116 2e-25
pir||A82833 indole-3-glycerol phosphate synthase XF0213 [importe... 116 3e-25
sp|P26938|TRPC_AZOBR INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 115 5e-25
sp|Q9ZFA7|TRPC_RHOSH INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 115 6e-25
sp|P20577|TRPC_PSEAE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 114 8e-25
sp|O06129|TRPC_MYCTU INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 114 1e-24
sp|Q9X7C7|TRPC_MYCLE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 113 2e-24
sp|O25867|TRPC_HELPY TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 112 4e-24
sp|P94327|TRPC_BRAJA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 111 5e-24
sp|Q92370|TRPG_SCHPO ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 109 2e-23
sp|Q9Z4X0|TRC2_STRCO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE 2 (IGP... 109 4e-23
sp|P24773|TRPG_PENCH ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 108 5e-23
pir||T39468 anthranilate synthase (EC 4.1.3.27) component II - f... 108 5e-23
sp|Q9XBM3|TRPC_ZYMMP INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 108 6e-23
sp|Q9ZJU8|TRPC_HELPJ TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 108 8e-23
pir||F82232 indole-3-glycerol phosphate synthase/ phosphoribosyl... 108 8e-23
sp|Q55508|TRPC_SYNY3 INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 107 1e-22
pir||H81216 indole-3-glycerol phosphate synthase NMB0275 [import... 107 1e-22
pir||G81794 indole-3-glycerol phosphate synthase (EC 4.1.1.48) N... 107 1e-22
sp|P05328|TRPG_ASPNG ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 107 1e-22
pir||S11161 anthranilate synthase multifunctional protein - Aspe... 107 1e-22
sp|P18483|TRPG_ASPAW ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 107 1e-22
sp|O68427|TRPC_BUCDN TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 106 2e-22
gb|AAA35176.1| (K01386) anthranilate synthase Component II:indol... 106 2e-22
gi|6322638 anthranilate synthase Component II and indole-3-phosp... 106 2e-22
sp|P22098|TRPC_VIBPA TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 105 4e-22
sp|P03964|TRPC_BACSU INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 104 7e-22
sp|P57366|TRPC_BUCAI TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 102 3e-21
sp|P00911|TRPC_ACICA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 102 4e-21
sp|P42393|TRPC_BUCAP TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 102 5e-21
gb|AAA65168.1| (U23496) anthranilate isomerase [Escherichia coli] 102 5e-21
sp|P06531|TRPG_EMENI ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 101 6e-21
dbj|BAA97002.1| (AB023039) indole-3-glycerol phosphate synthase ... 101 8e-21
gb|AAA73825.1| (U25423) anthranilate isomerase [Escherichia coli... 101 1e-20
gb|AAA73831.1| (U25425) anthranilate isomerase [Escherichia coli] 101 1e-20
gb|AAA73837.1| (U25426) anthranilate isomerase [Escherichia coli] 101 1e-20
gb|AAA73855.1| (U25429) anthranilate isomerase [Escherichia coli] 101 1e-20
pir||T44526 indole-3-glycerol-phosphate synthase (EC 4.1.1.48) [... 101 1e-20
gb|AAA65144.1| (U23491) anthranilate isomerase [Escherichia coli... 101 1e-20
gb|AAA65156.1| (U23493) anthranilate isomerase [Escherichia coli] 101 1e-20
pir||T47189 anthranilate isomerase [imported] - Escherichia coli... 101 1e-20
gb|AAB60039.1| (U23495) anthranilate isomerase [Escherichia coli] 101 1e-20
gb|AAB60044.1| (U23497) anthranilate isomerase [Escherichia coli] 101 1e-20
gb|AAB60050.1| (U23498) anthranilate isomerase [Escherichia coli... 101 1e-20
gb|AAA65174.1| (U23500) anthranilate isomerase [Escherichia coli... 101 1e-20
gb|AAB60054.1| (U23499) anthranilate isomerase [Escherichia coli] 99 3e-20
gb|AAA65150.1| (U23492) anthranilate isomerase [Escherichia coli] 99 5e-20
gb|AAA73795.1| (U25418) anthranilate isomerase [Escherichia coli] 99 5e-20
emb|CAA23664.1| (V00366) reading frame trpC [Escherichia coli] >... 98 7e-20
emb|CAA23673.1| (V00372) trpC [Escherichia coli] 98 7e-20
sp|P00909|TRPC_ECOLI TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 98 7e-20
sp|P49572|TRPC_ARATH INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE PRECUR... 98 7e-20
gb|AAD25838.1|AC006951_17 (AC006951) putative indole-3-glycerol ... 98 9e-20
sp|P00910|TRPC_SALTY TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 98 1e-19
sp|P46451|TRPC_HAEIN TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 98 1e-19
gb|AAF14253.1|AF132318_3 (AF132318) phosphoribosyl anthranilate ... 98 1e-19
pdb|1PII| N-(5'phosphoribosyl)anthranilate Isomerase (E.C.5.3.... 97 2e-19
pir||I54118 anthranilate isomerase - Escherichia coli >gi|775124... 97 2e-19
pir||GWEC indole-3-glycerol-phosphate synthase (EC 4.1.1.48) / p... 97 2e-19
sp|Q92411|TRPG_COCHE ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 96 3e-19
sp|P24920|TRPC_PHYPR TRYPTOPHAN BIOSYNTHESIS PROTEIN TRP1 [INCLU... 96 4e-19
sp|P25170|TRPG_PHACH ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 95 8e-19
sp|P00908|TRPG_NEUCR ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 94 2e-18
sp|P06560|TRPC_BRELA TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 92 5e-18
dbj|BAB13482.1| (AB028647) TRP1 [Flammulina velutipes] 92 5e-18
sp|P20409|TRPG_PHYBL ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 91 1e-17
gb|AAA33633.1| (M23177) trifunctional protein with glutamine ami... 91 1e-17
pir||S07305 trpC protein - Emericella nidulans >gi|2423|emb|CAA2... 90 2e-17
sp|Q44603|TRPC_BUCSC TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCL... 90 2e-17
emb|CAB37686.1| (AJ239573) anthranilate isomerase [Helicobacter ... 86 3e-16
emb|CAB37682.1| (AJ239569) anthranilate isomerase [Helicobacter ... 86 4e-16
emb|CAB37689.1| (AJ239576) anthranilate isomerase [Helicobacter ... 86 4e-16
emb|CAB37685.1| (AJ239572) anthranilate isomerase [Helicobacter ... 85 5e-16
emb|CAB37688.1| (AJ239575) anthranilate isomerase [Helicobacter ... 85 5e-16
emb|CAB37690.1| (AJ239577) anthranilate isomerase [Helicobacter ... 85 9e-16
sp|Q9Y8T7|TRPC_AERPE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 82 4e-15
sp|Q02584|TRPC_RHOCA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)... 80 2e-14
emb|CAC11937.1| (AL445065) indole-3-glycerol-phosphate synthase ... 71 9e-12
>pir||C75163 indole-3-glycerol-phosphate synthase (EC 4.1.1.48) PAB2043 -
Pyrococcus abyssi (strain Orsay)
>gi|5457896|emb|CAB49386.1| (AJ248284) INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (EC 4.1.1.48) (IGPS). [Pyrococcus
abyssi]
Length = 229
Score = 453 bits (1153), Expect = e-127
Identities = 229/229 (100%), Positives = 229/229 (100%)
Query: 1 MVIFGLSRRIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPK 60
MVIFGLSRRIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPK
Sbjct: 1 MVIFGLSRRIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPK 60
Query: 61 YFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDH 120
YFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDH
Sbjct: 61 YFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDH 120
Query: 121 AREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKF 180
AREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKF
Sbjct: 121 AREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKF 180
Query: 181 VKVSESGITTLEDLKVALKYADAALIGTALMKTEDPEKLLKSFVEAKIC 229
VKVSESGITTLEDLKVALKYADAALIGTALMKTEDPEKLLKSFVEAKIC
Sbjct: 181 VKVSESGITTLEDLKVALKYADAALIGTALMKTEDPEKLLKSFVEAKIC 229
>sp|Q9YGB5|TRPC_PYRKO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)
>gi|11268623|pir||T43922 indole-3-glycerol-phosphate
synthase (EC 4.1.1.48) [imported] - Pyrococcus
kodakaraensis >gi|5545304|dbj|BAA82545.1| (AB030011)
indole-3-glycerol phosphate synthase [Thermococcus
kodakaraensis]
Length = 227
Score = 354 bits (900), Expect = 4e-97
Identities = 175/227 (77%), Positives = 203/227 (89%)
Query: 2 VIFGLSRRIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKY 61
++FGLSR I++ KN IIAELKVYSPKYGDLL+GR+P EILR YERAGAVGISYITDPKY
Sbjct: 1 MVFGLSRAIRKAEKNAIIAELKVYSPKYGDLLKGRNPFEILRAYERAGAVGISYITDPKY 60
Query: 62 FRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHA 121
FRG+F+F ++LC+ETELPVLRKDFI +KEE+E+TAEAG SAVLLITRLLK++LPEFVD A
Sbjct: 61 FRGSFEFLRKLCRETELPVLRKDFIASKEEVERTAEAGASAVLLITRLLKEELPEFVDFA 120
Query: 122 REHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFV 181
+EHGLDTLVEVH+ EEL IA+QT+STMIGINNRDIGKLELDDGNVSLT KLAPLIP ++V
Sbjct: 121 KEHGLDTLVEVHSEEELAIALQTDSTMIGINNRDIGKLELDDGNVSLTEKLAPLIPKRYV 180
Query: 182 KVSESGITTLEDLKVALKYADAALIGTALMKTEDPEKLLKSFVEAKI 228
KVSESGI EDLK AL++ADAALIGTALMKT D E+ L+ VE ++
Sbjct: 181 KVSESGIAGTEDLKRALRHADAALIGTALMKTPDREEFLRKLVEVEV 227
>gi|11499197 anthranilate synthase component II (trpD) [Archaeoglobus fulgidus]
>gi|8479063|sp|O28668|TRCD_ARCFU TRYPTOPHAN BIOSYNTHESIS
PROTEIN TRPCD [INCLUDES: INDOLE-3-GLYCEROL PHOSPHATE
SYNTHASE (IGPS); ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE
] >gi|7482905|pir||C69450 anthranilate synthase
component II (trpD) homolog - Archaeoglobus fulgidus
>gi|2648956|gb|AAB89645.1| (AE000992) anthranilate
synthase component II (trpD) [Archaeoglobus fulgidus]
Length = 546
Score = 192 bits (484), Expect = 2e-48
Identities = 111/225 (49%), Positives = 152/225 (67%), Gaps = 8/225 (3%)
Query: 1 MVIFGLSRRIKRCTK---NPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYIT 57
M+ FG +K +K N +IAE+KV SP +GDLLRGR +ILR YE+AGA ISYIT
Sbjct: 1 MMDFGFVDSLKGASKRGKNAVIAEVKVRSPIHGDLLRGRRIEDILRAYEKAGAAAISYIT 60
Query: 58 DPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEF 117
+ F GNF+ K++ T+LPVLRKDFI ++E+E+TAE +A+LLI R LK++ E
Sbjct: 61 -AEQFSGNFETLKKIVGLTDLPVLRKDFIRGRKEVERTAEVEAAALLLIARHLKERTAEM 119
Query: 118 VDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIP 177
VD EHG++ LVEVH E+L A N+ + INNRDI ++E D G++ +TAK+A I
Sbjct: 120 VDFCFEHGIEPLVEVHHAEDLVYA--ENARAVLINNRDIDRMERDGGSIDVTAKIAEKI- 176
Query: 178 DKFVKVSESGITTLEDLKVALKYADAALIGTALMKTEDPEKLLKS 222
+ KVS SGI ++EDL L+Y DAALIGTA M E+ E+ +++
Sbjct: 177 -RAFKVSGSGIGSVEDLLFVLQYVDAALIGTAFMMAENTEEFVQT 220
>sp|Q58328|TRPC_METJA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|2129080|pir||F64414
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Methanococcus jannaschii >gi|1591591|gb|AAB98923.1|
(U67535) indole-3-glycerol phosphate
synthase/phosphoribosylanthranilate isomerase (trpC)
[Methanococcus jannaschii]
Length = 266
Score = 168 bits (421), Expect = 5e-41
Identities = 94/223 (42%), Positives = 141/223 (63%), Gaps = 8/223 (3%)
Query: 6 LSRRIKRCT--KNPIIAELKVYSPKYGDL--LRGRDPLEILRRYERAGAVGISYITDPKY 61
LS+ IK+ KNPII E+K SP G + + D I GA +S +T+PKY
Sbjct: 46 LSKAIKKAKEIKNPIITEIKPSSPSKGSIREINLEDVKNIANEMVEGGATALSILTEPKY 105
Query: 62 FRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHA 121
F G++ + +E ++P+L KDFI +I+ +E G +AVLLI LK+ + EF+D+A
Sbjct: 106 FNGSYKNLI-VAREFDIPILMKDFIVDFYQIDVASEIGANAVLLIVSSLKEDIGEFLDYA 164
Query: 122 REHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFV 181
+E+ L+ LVE H+ +E+ IA+ + +IGINNRD+ L++D +S T KLAPLIP +
Sbjct: 165 KENDLECLVETHSEDEIDIALDAGAKIIGINNRDLKTLKID---LSTTEKLAPLIPKNKI 221
Query: 182 KVSESGITTLEDLKVALKYADAALIGTALMKTEDPEKLLKSFV 224
KV ESGI T E L LK+ DAALIG+++M++E+ + ++ FV
Sbjct: 222 KVGESGIYTKEQLNYVLKFTDAALIGSSIMESENIREKVREFV 264
>sp|O67657|TRPC_AQUAE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|7436778|pir||G70453
indole-3-glycerol phosphate synthase - Aquifex aeolicus
>gi|2984077|gb|AAC07616.1| (AE000756) indole-3-glycerol
phosphate synthase [Aquifex aeolicus]
Length = 257
Score = 150 bits (374), Expect = 2e-35
Identities = 92/212 (43%), Positives = 134/212 (62%), Gaps = 10/212 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
IIAE+K SP G++ + +P E + YE+AGA+ IS +TD KYF+G+ + + + + +
Sbjct: 49 IIAEVKKASPSEGNI-KEVNPEEQAKLYEKAGAIAISVLTDEKYFKGSLEDLRNVRESVK 107
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVEVHTLE 136
LP+LRKDF K +I + G VLLI R+L DK L E +D + E GL LVEV TL+
Sbjct: 108 LPLLRKDFTVHKVQILEAKAYGADIVLLIVRMLSDKELKELLDFSEELGLSPLVEVFTLD 167
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPD---KFVKVSESGITTLED 193
E K A+ + +IGINNRD+ ++D ++ T +LAP I D KFV +SESGI+ E+
Sbjct: 168 EAKRALDAGAKIIGINNRDLETFKVD---INKTKELAPKIKDLGAKFV-ISESGISKREE 223
Query: 194 LKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
+ + Y D LIGT+LMK+E+P + LK +
Sbjct: 224 ILELMNYQVDGFLIGTSLMKSENPYRKLKELL 255
>sp|P18304|TRPC_HALVO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|99228|pir||C36044
indole-3-glycerol-phosphate synthase (EC 4.1.1.48)
[validated] - Haloferax volcanii (strain WFD11)
>gi|149042|gb|AAA72862.1| (M36177)
indoleglycerolphosphate synthetase (trpC) [Haloferax
volcanii]
Length = 251
Score = 140 bits (349), Expect = 2e-32
Identities = 79/196 (40%), Positives = 122/196 (61%), Gaps = 8/196 (4%)
Query: 17 PIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKET 76
P+IAE+K SP + +R DP+E+ R GA +S +T+P++F G+ + +R+ +
Sbjct: 50 PVIAEVKPTSPTT-EGVREDDPVELAREMVAGGATALSVLTEPEHFGGSAESLRRIREAV 108
Query: 77 ELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREHGLDTLVEVHTLE 136
++PVLRKDFI + +++ VLLI R + + LP V+ AR+ G LVEVHT E
Sbjct: 109 DVPVLRKDFIMNEAQLDVVQS---DLVLLIARFVGEDLPALVEAARDRGFQPLVEVHTRE 165
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL-K 195
EL A+ + ++GINNRD+GKLE+D G +LAP P+ + V+ESG+ T++D +
Sbjct: 166 ELTAALAAGADIVGINNRDLGKLEVDLGTFE---ELAPEAPEDVLLVAESGVQTVDDARR 222
Query: 196 VALKYADAALIGTALM 211
+ ADA L+GTA+M
Sbjct: 223 MREAGADALLVGTAIM 238
>sp|Q01999|TRPC_LACLA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|421422|pir||S35127
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Lactococcus lactis subsp. lactis
>gi|149519|gb|AAA25226.1| (M87483) indoleglycerol
phosphate synthase [Lactococcus lactis]
Length = 264
Score = 133 bits (331), Expect = 2e-30
Identities = 74/207 (35%), Positives = 120/207 (57%), Gaps = 6/207 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP GD+ D ++ + YE+AGA IS +TDP +F+GN ++ + + +
Sbjct: 50 VIAEVKKASPSLGDINLEVDIVDQAKNYEQAGAAMISVLTDPVFFKGNIEYLCEISENVQ 109
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVEVHT 134
+P L KDFI K++I + AG + +LLI + ++ KL ++A GL+ LVE H
Sbjct: 110 IPTLNKDFIIDKKQINRAVNAGATVILLIVAVFENQYPKLQNLYNYALSLGLEVLVETHN 169
Query: 135 LEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL 194
EL+IA Q + +IG+NNR++ E+ N + L P + + +SESGI + +
Sbjct: 170 KAELEIAHQLGAKIIGVNNRNLKTFEVILQN---SVDLTPYFKEDSIYISESGIFSANEA 226
Query: 195 KVALKYADAALIGTALMKTEDPEKLLK 221
+ + L+GTALM++E+ EK LK
Sbjct: 227 QKVSDTFNGILVGTALMQSENLEKSLK 253
>dbj|BAB05380.1| (AP001512) indol-3-glycerol phosphate synthase [Bacillus
halodurans]
Length = 257
Score = 131 bits (325), Expect = 1e-29
Identities = 79/204 (38%), Positives = 121/204 (58%), Gaps = 6/204 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + P+EI + YE AGA IS +TD YF+G+ D+ ++ +
Sbjct: 42 LLAEVKKASPSKGLIRADFHPVEIGKSYEAAGADAISVLTDETYFQGHRDYLTKVKQAVN 101
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHAREHGLDTLVEVHTLE 136
+PVLRKDFI + +I ++ G A+LLI + +L E D A E GL+ LVEVH+ E
Sbjct: 102 IPVLRKDFIIDRAQILESVRIGADAILLIVSTIPTTRLKELYDEAHELGLECLVEVHSEE 161
Query: 137 EL-KIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL- 194
E+ ++ T+IG+NNR++ E D V+ T K+A +IP + +SESG+ T +DL
Sbjct: 162 EIAELFSAFTPTLIGVNNRNLKTFETD---VAQTEKMAQVIPHGTMFLSESGLYTYDDLQ 218
Query: 195 KVALKYADAALIGTALMKTEDPEK 218
+V A L+G +LM+ PE+
Sbjct: 219 RVKRAGATGVLVGESLMRASSPEE 242
>pir||E81395 indole-3-glycerol phosphate synthase (EC 4.1.1.48) Cj0498
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6967969|emb|CAB75136.1| (AL139075) indole-3-glycerol
phosphate synthase [Campylobacter jejuni]
Length = 258
Score = 129 bits (321), Expect = 3e-29
Identities = 81/220 (36%), Positives = 126/220 (56%), Gaps = 6/220 (2%)
Query: 8 RRIKRCTKN-PIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNF 66
+ +KR K IIAE+K SP G + DPL I YE+ A IS +T+P +F+G+
Sbjct: 42 KALKRVEKEVKIIAEVKKASPSKGVIREDFDPLSIALNYEKNKAAAISVLTEPHFFKGSL 101
Query: 67 DFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHG 125
++ + + T++P+LRKDFI + +I + G VLLI ++L K L + ++ AR G
Sbjct: 102 EYLSLIRRYTQIPLLRKDFIFDEYQILEALVYGADFVLLIAKMLSMKELKKLLEFARHLG 161
Query: 126 LDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSE 185
L+ LVE+H E+L AI + +IGIN+R++ +D +SL KL P IP+ + ++E
Sbjct: 162 LEALVEIHDKEDLSKAIFAGADIIGINHRNLEDFTMD---MSLCEKLIPQIPNSKIIIAE 218
Query: 186 SGITTLEDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
SG+ E L+ DA LIG M+ +D K LK+ +
Sbjct: 219 SGLENKEFLEHLQNLGVDAFLIGEYFMREKDEGKALKALL 258
>sp|Q06121|TRPC_SULSO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|421731|pir||C40635
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) TrpC
- Sulfolobus solfataricus >gi|1633216|pdb|1IGS|
Indole-3-Glycerolphosphate Synthase From Sulfolobus
Solfataricus At 2.0 A Resolution >gi|2392402|pdb|1JUL|
Indole-3-Glycerolphosphate Synthase From Sulfolobus
Solfataricus In A Second Orthorhombic Crystal Form
>gi|2392401|pdb|1JUK| Indole-3-Glycerolphosphate
Synthase From Sulfolobus Solfataricus In A Trigonal
Crystal Form >gi|152939|gb|AAA73381.1| (M98048)
indole-3-glycerol phosphate synthase [Sulfolobus
solfataricus] >gi|1004325|emb|CAA90313.1| (Z50014)
indole-3-glycerol phosphate synthase [Sulfolobus
solfataricus]
Length = 248
Score = 129 bits (320), Expect = 4e-29
Identities = 82/227 (36%), Positives = 134/227 (58%), Gaps = 14/227 (6%)
Query: 3 IFGLSRRIKRCTKN---PIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDP 59
I L+ RI K IIAE K SP D+ RDP+E + ER AVG+S +T+
Sbjct: 30 IISLNERILEFNKRNITAIIAEYKRKSPSGLDV--ERDPIEYSKFMERY-AVGLSILTEE 86
Query: 60 KYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFV 118
KYF G+++ +++ +P+L KDFI + +I+ G VLLI ++L ++ L +
Sbjct: 87 KYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLL 146
Query: 119 DHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPD 178
++AR +G++ L+E++ +L IA++ + IGIN+RD+ LE++ N KL +IP
Sbjct: 147 EYARSYGMEPLIEINDENDLDIALRIGARFIGINSRDLETLEINKEN---QRKLISMIPS 203
Query: 179 KFVKVSESGITTLEDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
VKV+ESGI+ +++ K +A LIG++LM+ +PEK +K F+
Sbjct: 204 NVVKVAESGISERNEIEELRKLGVNAFLIGSSLMR--NPEK-IKEFI 247
>gb|AAK41177.1| Indole-3-glycerol phosphate synthase (trpC) [Sulfolobus
solfataricus]
Length = 248
Score = 129 bits (320), Expect = 4e-29
Identities = 82/227 (36%), Positives = 134/227 (58%), Gaps = 14/227 (6%)
Query: 3 IFGLSRRIKRCTKN---PIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDP 59
I L+ RI K IIAE K SP D+ RDP+E + ER AVG+S +T+
Sbjct: 30 IISLNERILEFNKRNITAIIAEYKRKSPSGLDV--ERDPIEYSKFMERY-AVGLSILTEE 86
Query: 60 KYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFV 118
KYF G+++ +++ +P+L KDFI + +I+ G VLLI ++L ++ L +
Sbjct: 87 KYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLL 146
Query: 119 DHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPD 178
++AR +G++ L+E++ +L IA++ + IGIN+RD+ LE++ N KL +IP
Sbjct: 147 EYARSYGMEPLIEINDENDLDIALRIGARFIGINSRDLETLEINKEN---QRKLISMIPS 203
Query: 179 KFVKVSESGITTLEDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
VKV+ESGI+ +++ K +A LIG++LM+ +PEK +K F+
Sbjct: 204 NVVKVAESGISERNEIEELRKLGVNAFLIGSSLMR--NPEK-IKEFI 247
>pir||S50179 indole-3-glycerol-phosphate synthase - Sulfolobus solfataricus
Length = 248
Score = 129 bits (320), Expect = 4e-29
Identities = 82/227 (36%), Positives = 134/227 (58%), Gaps = 14/227 (6%)
Query: 3 IFGLSRRIKRCTKN---PIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDP 59
I L+ RI K IIAE K SP D+ RDP+E + ER AVG+S +T+
Sbjct: 30 IISLNERILEFNKRNITAIIAEYKRKSPSGLDV--ERDPIEYSKFMERY-AVGLSILTEE 86
Query: 60 KYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFV 118
KYF G+++ +++ +P+L KDFI + +I+ G VLLI ++L ++ L +
Sbjct: 87 KYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLL 146
Query: 119 DHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPD 178
++AR +G++ L+E++ +L IA++ + IGIN+RD+ LE++ N KL +IP
Sbjct: 147 EYARSYGMEPLIEINDENDLDIALRIGARFIGINSRDLETLEINKEN---QRKLISMIPS 203
Query: 179 KFVKVSESGITTLEDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
VKV+ESGI+ +++ K +A LIG++LM+ +PEK +K F+
Sbjct: 204 NVVKVAESGISERNEIEELRKLGVNAFLIGSSLMR--NPEK-IKEFI 247
>pdb|1A53| Complex Of Indole-3-Glycerolphosphate Synthase From Sulfolobus
Solfataricus With Indole-3-Glycerolphosphate At 2.0 A
Resolution
Length = 247
Score = 129 bits (320), Expect = 4e-29
Identities = 82/227 (36%), Positives = 134/227 (58%), Gaps = 14/227 (6%)
Query: 3 IFGLSRRIKRCTKN---PIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDP 59
I L+ RI K IIAE K SP D+ RDP+E + ER AVG+S +T+
Sbjct: 29 IISLNERILEFNKRNITAIIAEYKRKSPSGLDV--ERDPIEYSKFMERY-AVGLSILTEE 85
Query: 60 KYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFV 118
KYF G+++ +++ +P+L KDFI + +I+ G VLLI ++L ++ L +
Sbjct: 86 KYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLL 145
Query: 119 DHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPD 178
++AR +G++ L+E++ +L IA++ + IGIN+RD+ LE++ N KL +IP
Sbjct: 146 EYARSYGMEPLIEINDENDLDIALRIGARFIGINSRDLETLEINKEN---QRKLISMIPS 202
Query: 179 KFVKVSESGITTLEDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
VKV+ESGI+ +++ K +A LIG++LM+ +PEK +K F+
Sbjct: 203 NVVKVAESGISERNEIEELRKLGVNAFLIGSSLMR--NPEK-IKEFI 246
>pir||H75396 indole-3-glycerol phosphate synthase - Deinococcus radiodurans
(strain R1) >gi|6459183|gb|AAF10995.1|AE001987_3
(AE001987) indole-3-glycerol phosphate synthase
[Deinococcus radiodurans]
Length = 267
Score = 126 bits (314), Expect = 2e-28
Identities = 75/198 (37%), Positives = 108/198 (53%), Gaps = 1/198 (0%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + DP + R Y GA IS +T+P++F G+ + + + +E
Sbjct: 60 LIAEVKQASPSEG-AIAALDPAQAARAYAEGGAAAISCLTEPRHFGGSPEALRAVVAASE 118
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREHGLDTLVEVHTLEE 137
+PVLRKDF+ + + AE G A LL+ +L ++LPEF+ GLD LVEVH E
Sbjct: 119 VPVLRKDFVVHPAMLREAAEWGAGAALLMVSVLGERLPEFLAMTEHLGLDALVEVHDERE 178
Query: 138 LKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKVA 197
L IA+ ++GINNRD+ L++D G A V V+ESG DL+
Sbjct: 179 LDIALAAGPRILGINNRDLTTLKIDLGVSPHLMARARAAGFSGVLVAESGYRAPADLREV 238
Query: 198 LKYADAALIGTALMKTED 215
ADA L+GT+L + D
Sbjct: 239 YGLADAVLVGTSLAGSGD 256
>sp|P17217|TRPC_LACCA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|80560|pir||JS0341
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Lactobacillus casei >gi|216757|dbj|BAA00384.1| (D00496)
trpC protein [Lactobacillus casei]
Length = 260
Score = 125 bits (310), Expect = 6e-28
Identities = 74/210 (35%), Positives = 120/210 (56%), Gaps = 5/210 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G ++ L I + Y++AGA IS +T+P YF G+ + K + ++
Sbjct: 52 VIAEVKKASPSKGTIVTDFPYLAIAKAYDQAGADAISVLTEPDYFNGHLHYLKEISQQVS 111
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
+P LRKDF I + G +LLI +L D +L ++ A + G+ +VE +T
Sbjct: 112 VPTLRKDFTIDPYMIYEAKANGAVIILLIVAILTDQQLRDYRQLAEKLGMHAIVEAYTAA 171
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL-K 195
E+ A+Q+ + +IGINNR++ +D N + KL ++PD V+ESGI T ED+ K
Sbjct: 172 EVTRALQSGAKIIGINNRNLKDFRVDFTN---SLKLRAMVPDNIPVVAESGIKTQEDVEK 228
Query: 196 VALKYADAALIGTALMKTEDPEKLLKSFVE 225
+A +A LIG LM++ ++L+ +F E
Sbjct: 229 LAAAGFNAILIGETLMRSNQKKQLIAAFKE 258
>sp|P26939|TRPC_METTM INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|99116|pir||F40362
trpC protein - Methanobacterium thermoautotrophicum
(strain Marburg) >gi|149747|gb|AAA73030.1| (M65060)
indoleglycerolphosphate synthase [Methanobacterium
thermoautotrophicum]
Length = 274
Score = 124 bits (308), Expect = 1e-27
Identities = 80/210 (38%), Positives = 123/210 (58%), Gaps = 8/210 (3%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+I E K SP G GR E++ Y R GA +S IT+ +YF G+ +F + E
Sbjct: 51 LICEYKRASPSSGRTY-GRGLHEMMEVY-REGADAVSVITENRYFHGSIEFLRE-ASEYG 107
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREHGLDTLVEVHTLEE 137
+P+L KDF+ + +I + +G S+VL+IT + D L ++ RE ++ LVE H+ +
Sbjct: 108 IPLLMKDFVVDEYQIYQARASGASSVLIITGVFPD-LESGIETCRELSMEPLVECHSAID 166
Query: 138 LKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKV- 196
+ AI+ + +IG+NNR++ LE+D + T LAPL+PD+ + VSESG+ ED ++
Sbjct: 167 IYRAIEAGAELIGVNNRNLETLEVD---LERTRALAPLVPDELLLVSESGVMGPEDAEIL 223
Query: 197 ALKYADAALIGTALMKTEDPEKLLKSFVEA 226
A ADA LIGT+LM DP +LL + A
Sbjct: 224 AGCGADALLIGTSLMLASDPRELLDEIMAA 253
>gb|AAG18886.1| (AE004991) indole-3-glycerol-phosphate synthase; TrpC
[Halobacterium sp. NRC-1]
Length = 251
Score = 121 bits (301), Expect = 6e-27
Identities = 74/198 (37%), Positives = 110/198 (55%), Gaps = 8/198 (4%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ PIIAE+K SP D DP E+ R GA +S +T+P +F G+ D + +
Sbjct: 47 RTPIIAEVKPTSPTT-DTEHSGDPAELAREMVAGGAAAVSVLTEPHHFDGSTDALRAIRD 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREHGLDTLVEVHT 134
++PVLRKDF+ T+ +++ A AVLLI R L D L + + AR+ G LVEVH+
Sbjct: 106 AVDVPVLRKDFLLTEPQLDAVA---ADAVLLIARFLGDDLGDMLAAARDRGFQALVEVHS 162
Query: 135 LEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL 194
EL A+ ++ +IG+NNRD+ L +D + +AP P V+ESGI T D
Sbjct: 163 PRELARAVDADADIIGVNNRDLTALTVD---LDTFGAVAPEAPADVTLVAESGIATPTDA 219
Query: 195 K-VALKYADAALIGTALM 211
+ + AD L+G+A+M
Sbjct: 220 RTMRAAGADGLLVGSAIM 237
>emb|CAB60751.1| (Y18640) indole-3-glycerol phosphate synthase [Staphylococcus
aureus]
Length = 260
Score = 121 bits (300), Expect = 8e-27
Identities = 81/221 (36%), Positives = 119/221 (53%), Gaps = 6/221 (2%)
Query: 10 IKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFF 69
I++ K IIAE+K SP DL RD + + Y++ GA +S +TD KYF G+F+
Sbjct: 42 IEKEPKLAIIAEIKSKSPTVNDLPE-RDLSQQISDYDQYGANAVSILTDEKYFSGSFERL 100
Query: 70 KRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDT 128
+ L +T LPVL KDFI +I+ +AG S +LLI +L DK L + ++A L+
Sbjct: 101 QALTTKTTLPVLCKDFIIDPLQIDVAKQAGASMILLIVNILSDKQLKDLYNYAISQNLEV 160
Query: 129 LVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGI 188
LVEVH EL+ A + N+ +IG+NNRD+ + NV T + +SESGI
Sbjct: 161 LVEVHDRHELERAYKVNAKLIGVNNRDLKRFVT---NVEHTNTILENKKTNHYYISESGI 217
Query: 189 TTLEDL-KVALKYADAALIGTALMKTEDPEKLLKSFVEAKI 228
D+ K+ D LIG ALM+ ++ + L K+
Sbjct: 218 HDASDVRKILHSGIDGLLIGEALMRCDNLSEFLPQLKMQKV 258
>sp|O27694|TRPC_METTH INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|7436777|pir||E69088
indole-3-glycerol phosphate synthase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622785|gb|AAB86129.1| (AE000924) indole-3-glycerol
phosphate synthase [Methanobacterium
thermoautotrophicum]
Length = 272
Score = 121 bits (300), Expect = 8e-27
Identities = 79/213 (37%), Positives = 121/213 (56%), Gaps = 8/213 (3%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
K +I E K SP G + R E++ Y+ A +S +TD KYF+G+ D
Sbjct: 46 KVSLICEYKRASPSMGRISE-RGLEEMMEVYQDL-ADAVSIVTDGKYFKGSLDLLSG-AT 102
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREHGLDTLVEVHT 134
+ P+L KDF+ + +I + +G S+VLLIT + D L + RE ++ LVE HT
Sbjct: 103 DYGKPLLMKDFLVDEYKIYQARASGASSVLLITGVFPD-LEAGIQKCRELSMEPLVECHT 161
Query: 135 LEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL 194
++ A++ + +IG+NNRD+ E+D + T LAPL+PD+ + VSESG+ ED
Sbjct: 162 SLDIFRALEAGAEIIGVNNRDLETFEVD---LERTHALAPLVPDELILVSESGVRGPEDA 218
Query: 195 KVALKY-ADAALIGTALMKTEDPEKLLKSFVEA 226
++ Y ADA LIGTA M ++P +LL+ V+A
Sbjct: 219 EILAGYGADALLIGTAPMSAQNPRELLEEIVDA 251
>sp|P70937|TRPC_BACME INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)
>gi|1519710|gb|AAB07592.1| (U67986) indole glycerol
phosphate synthetase [Bacillus megaterium]
Length = 255
Score = 117 bits (291), Expect = 1e-25
Identities = 77/207 (37%), Positives = 116/207 (55%), Gaps = 6/207 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + P+EI + YE+ A +S +TD YF+G+ F + +
Sbjct: 42 LIAEVKKASPSKGLIKENFQPVEIAKAYEKGKADALSVLTDQHYFQGHRTFLSDIKQHVS 101
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
+PVLRKDFI ++E++A G A+LLI L+ KL E A E LD LVEVH+LE
Sbjct: 102 VPVLRKDFIIDSIQVEESARIGADAILLIGEALEPLKLQELYLQAAEKELDCLVEVHSLE 161
Query: 137 EL-KIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
L K+ +IGINNR++ E ++ T ++A +P + VSESGI +D+
Sbjct: 162 TLEKLLAVFTPKIIGINNRNLHTFET---SLQQTKEIAKHVPKDQLLVSESGIYLYDDVS 218
Query: 196 -VALKYADAALIGTALMKTEDPEKLLK 221
V A A L+G +LM+ ++ K ++
Sbjct: 219 YVKEAGAKAILVGESLMRQDNQTKAIE 245
>sp|P20578|TRPC_PSEPU INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|94921|pir||D35115
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Pseudomonas putida >gi|1052830|gb|AAA80555.1| (M33799)
indoleglycerol phosphate synthetase [Pseudomonas putida]
Length = 277
Score = 117 bits (290), Expect = 1e-25
Identities = 73/202 (36%), Positives = 113/202 (55%), Gaps = 6/202 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + P EI YE+ GA +S +TD YF+G ++ ++
Sbjct: 58 VIAEIKKASPSKGVIREHFVPAEIAVSYEKGGATCLSVLTDVDYFQGADEYLQQARAAVS 117
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
LPV+RKDF+ +I + G VLLI L D K+ E A++ GLD LVEVH +
Sbjct: 118 LPVIRKDFMVDPYQIVEARALGADCVLLIVSALDDVKMAELAATAKDVGLDVLVEVHDGD 177
Query: 137 ELKIAIQTNST-MIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
EL+ A++T T ++G+NNR++ E+ ++ T L P IP + ++ESGI D++
Sbjct: 178 ELERALKTLDTPLVGVNNRNLHTFEV---SLETTLDLLPRIPRDRLAITESGILNRADVE 234
Query: 196 -VALKYADAALIGTALMKTEDP 216
+A+ + L+G A M+ E P
Sbjct: 235 LMAINEVYSFLVGEAFMRAEQP 256
>sp|O68814|TRC1_STRCO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE 1 (IGPS)
>gi|3722219|gb|AAC63500.1| (AF054585) indoleglycerol
phosphate synthase [Streptomyces coelicolor A3(2)]
Length = 269
Score = 117 bits (290), Expect = 1e-25
Identities = 75/211 (35%), Positives = 111/211 (52%), Gaps = 5/211 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+I E+K SP G L DP + YE GA IS +T+ + F G+ + +
Sbjct: 51 VICEVKRSSPSKGALAAIADPAGLAADYEAGGAAVISVLTEERRFGGSLADLDSVRARVD 110
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
+PVLRKDFI T ++ + G VLLI L+ L ++ A GL LVEVH +
Sbjct: 111 IPVLRKDFIVTSYQLWEARAHGADLVLLIVAALEQPALESLIERAESIGLTPLVEVHDED 170
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL-K 195
E++ A+ + +IG+N R++ LE+D G ++AP IP VKV+ESG+ DL
Sbjct: 171 EVERAVDAGAKVIGVNARNLKTLEVDRGTFE---RVAPEIPAHIVKVAESGVRGPHDLIA 227
Query: 196 VALKYADAALIGTALMKTEDPEKLLKSFVEA 226
A + ADA L+G +L+ DP+ + V A
Sbjct: 228 YANEGADAVLVGESLVTGRDPKTAVSDLVAA 258
>gb|AAD35233.1|AE001699_10 (AE001699) indole-3-glycerol phosphate synthase [Thermotoga
maritima]
Length = 230
Score = 117 bits (290), Expect = 1e-25
Identities = 73/206 (35%), Positives = 115/206 (55%), Gaps = 6/206 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
IIAE K SP GD+ + +R Y+ A IS +T+ YF+G+ F + T
Sbjct: 22 IIAEFKKASPSAGDINADASLEDFIRMYDEL-ADAISILTEKHYFKGDPAFVRAARNLTC 80
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVEVHTLE 136
P+L KDF +++ + G A+L+I R+L +++ E + A E G+D+LVEVH+ E
Sbjct: 81 RPILAKDFYIDTVQVKLASSVGADAILIIARILTAEQIKEIYEAAEELGMDSLVEVHSRE 140
Query: 137 EL-KIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
+L K+ +IGIN RD+ E+ ++ +L PL+PD V V+ESGI +LK
Sbjct: 141 DLEKVFSVIRPKIIGINTRDLDTFEIKK---NVLWELLPLVPDDTVVVAESGIKDPRELK 197
Query: 196 VALKYADAALIGTALMKTEDPEKLLK 221
+A L+GT++MK E+P + L+
Sbjct: 198 DLRGKVNAVLVGTSIMKAENPRRFLE 223
>pir||T35068 indole-3-glycerol-phosphate synthase - Streptomyces coelicolor
>gi|5596784|emb|CAB51431.1| (AL096884) indoleglycerol
phosphate synthase [Streptomyces coelicolor A3(2)]
Length = 269
Score = 117 bits (290), Expect = 1e-25
Identities = 75/211 (35%), Positives = 111/211 (52%), Gaps = 5/211 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+I E+K SP G L DP + YE GA IS +T+ + F G+ + +
Sbjct: 51 VICEVKRSSPSKGALAAIADPAGLAADYEAGGAAVISVLTEERRFGGSLADLDSVRARVD 110
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
+PVLRKDFI T ++ + G VLLI L+ L ++ A GL LVEVH +
Sbjct: 111 IPVLRKDFIVTSYQLWEARAHGADLVLLIVAALEQPALESLIERAESIGLTPLVEVHDED 170
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL-K 195
E++ A+ + +IG+N R++ LE+D G ++AP IP VKV+ESG+ DL
Sbjct: 171 EVERAVDAGAKVIGVNARNLKTLEVDRGTFE---RVAPEIPAHIVKVAESGVRGPHDLIA 227
Query: 196 VALKYADAALIGTALMKTEDPEKLLKSFVEA 226
A + ADA L+G +L+ DP+ + V A
Sbjct: 228 YANEGADAVLVGESLVTGRDPKTAVSDLVAA 258
>sp|Q56319|TRPC_THEMA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)
Length = 252
Score = 117 bits (290), Expect = 1e-25
Identities = 73/206 (35%), Positives = 115/206 (55%), Gaps = 6/206 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
IIAE K SP GD+ + +R Y+ A IS +T+ YF+G+ F + T
Sbjct: 44 IIAEFKKASPSAGDINADASLEDFIRMYDEL-ADAISILTEKHYFKGDPAFVRAARNLTC 102
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVEVHTLE 136
P+L KDF +++ + G A+L+I R+L +++ E + A E G+D+LVEVH+ E
Sbjct: 103 RPILAKDFYIDTVQVKLASSVGADAILIIARILTAEQIKEIYEAAEELGMDSLVEVHSRE 162
Query: 137 EL-KIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
+L K+ +IGIN RD+ E+ ++ +L PL+PD V V+ESGI +LK
Sbjct: 163 DLEKVFSVIRPKIIGINTRDLDTFEIKK---NVLWELLPLVPDDTVVVAESGIKDPRELK 219
Query: 196 VALKYADAALIGTALMKTEDPEKLLK 221
+A L+GT++MK E+P + L+
Sbjct: 220 DLRGKVNAVLVGTSIMKAENPRRFLE 245
>pir||S59047 indole-3-glycerol phosphate synthase - Thermotoga maritima (strain
MSB8) >gi|3980232|emb|CAA63389.1| (X92729)
indoleglycerol phosphate synthase [Thermotoga maritima]
Length = 252
Score = 116 bits (288), Expect = 2e-25
Identities = 73/206 (35%), Positives = 114/206 (54%), Gaps = 6/206 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
IIAE K SP GD+ + +R Y+ A IS +T+ YF+G+ F + T
Sbjct: 44 IIAEFKKASPSAGDINADASLEDFIRMYDEL-ADAISILTEKHYFKGDPAFVRAARNLTC 102
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVEVHTLE 136
P+L KDF +++ + G A+L+I R+L +++ E + A E G+D+LVEVH+ E
Sbjct: 103 RPILAKDFYIDTVQVKLASSVGADAILIIARILTAEQIKEIYEAAEELGMDSLVEVHSRE 162
Query: 137 EL-KIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
+L K+ +IGIN RD+ E+ ++ +L PL+PD V V+ESGI +LK
Sbjct: 163 DLEKVFSVIRPKIIGINTRDLDTFEIKK---NVLWELLPLVPDDTVVVAESGIKDPRELK 219
Query: 196 VALKYADAALIGTALMKTEDPEKLLK 221
A L+GT++MK E+P + L+
Sbjct: 220 DLRGKVKAVLVGTSIMKAENPRRFLE 245
>pir||A82833 indole-3-glycerol phosphate synthase XF0213 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9105020|gb|AAF83026.1|AE003875_1 (AE003875)
indole-3-glycerol phosphate synthase [Xylella
fastidiosa]
Length = 264
Score = 116 bits (287), Expect = 3e-25
Identities = 77/208 (37%), Positives = 114/208 (54%), Gaps = 9/208 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G L P EI YE GA +S +TD +F+G+ D+ +
Sbjct: 56 VIAEIKKASPSKGVLREDFRPAEIAISYELGGASCLSVLTDVHFFKGHDDYLSQARDACT 115
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
LPVLRKDF ++ + G +LLI L D +L + A + G+D LVEVH ++
Sbjct: 116 LPVLRKDFTIDPYQVYEARVLGADCILLIVAALDDAQLVDLSGLALQLGMDVLVEVHDID 175
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSL--TAKLAPLIPDKFVKVSESGITTLEDL 194
EL+ AIQ ++ +IGINNR++ NVSL T + L+P + VSESGI T D+
Sbjct: 176 ELERAIQISAPLIGINNRNLSTF-----NVSLETTLTMKGLVPRDRLLVSESGILTSADV 230
Query: 195 -KVALKYADAALIGTALMKTEDPEKLLK 221
++ +A L+G A M+ +P + L+
Sbjct: 231 QRLRAAGVNAFLVGEAFMRATEPGESLR 258
>sp|P26938|TRPC_AZOBR INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|94625|pir||S17705
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Azospirillum brasilense >gi|48844|emb|CAA40986.1|
(X57853) indoleglycerolphospate synthase [Azospirillum
brasilense]
Length = 262
Score = 115 bits (285), Expect = 5e-25
Identities = 73/200 (36%), Positives = 110/200 (54%), Gaps = 5/200 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + DP + R Y GA +S +TD YF+G D+ +
Sbjct: 56 LIAEIKKASPSKGLIRPDFDPPSLARAYRGGGATCLSVLTDEPYFQGCDDYLLSARAAVD 115
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
LPVLRKDF+ +I ++ G +L+I L D + E D A GLD LVEVH E
Sbjct: 116 LPVLRKDFMVDPYQIAESRALGADCILIIMAALSDAQAVEIEDAAIAWGLDVLVEVHNRE 175
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDL-K 195
EL A+ + ++G+NNR++ L +D ++ T +LA +P + V+ESG+ + DL +
Sbjct: 176 ELDRALALKTPLLGVNNRNLKTLAVD---IATTEELAAHVPADRMLVAESGLYSPADLSR 232
Query: 196 VALKYADAALIGTALMKTED 215
+A A L+G +LM+ ED
Sbjct: 233 MAAVGARCFLVGESLMRQED 252
>sp|Q9ZFA7|TRPC_RHOSH INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)
>gi|11268611|pir||T46856 indole-3-glycerol-phosphate
synthase (EC 4.1.1.48) [imported] - Rhodobacter
sphaeroides >gi|4185547|gb|AAD09119.1| (AF108766)
indole-3-glycerol phosphate synthase [Rhodobacter
sphaeroides]
Length = 270
Score = 115 bits (284), Expect = 6e-25
Identities = 74/209 (35%), Positives = 113/209 (53%), Gaps = 5/209 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + D + R YE GA +S +TD F+G DF ++ + +
Sbjct: 55 LIAEIKKASPSKGLIREDFDVPALARAYETGGATCLSVLTDGPSFQGADDFLRQAREAVK 114
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREH-GLDTLVEVHTLE 136
LP LRKDF+ ++ + G +L+I + D ++ A H G+D LVEVH+ E
Sbjct: 115 LPCLRKDFLYDTYQVAEARALGADCILIIMASVTDSQALELEAAASHWGMDVLVEVHSRE 174
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKV 196
EL A S +IGINNR++ E+ ++ +T LA +P+ + VSESG+ T EDL
Sbjct: 175 ELARAEHLKSRLIGINNRNLDTFEV---SLDVTRDLARRVPEDRLIVSESGLHTPEDLAD 231
Query: 197 ALKY-ADAALIGTALMKTEDPEKLLKSFV 224
+Y A LIG +LM+ D E ++ +
Sbjct: 232 LARYGARCFLIGESLMRQADVEAATRAIL 260
>sp|P20577|TRPC_PSEAE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|94823|pir||C35114
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Pseudomonas aeruginosa >gi|11350513|pir||A83564
indole-3-glycerol-phosphate synthase PA0651 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|151235|gb|AAA25825.1| (M33814) trpC protein (gtg
start codon) [Pseudomonas aeruginosa]
>gi|9946528|gb|AAG04040.1|AE004500_6 (AE004500)
indole-3-glycerol-phosphate synthase [Pseudomonas
aeruginosa]
Length = 278
Score = 114 bits (283), Expect = 8e-25
Identities = 84/220 (38%), Positives = 116/220 (52%), Gaps = 9/220 (4%)
Query: 6 LSRRIKRCTKNP-IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRG 64
L R KR K P +IAE+K SP G L P EI R YE GA +S +TD +F+G
Sbjct: 47 LLERAKR--KEPAVIAEIKKASPSKGVLREHFVPAEIARSYEAGGAACLSVLTDVDFFQG 104
Query: 65 NFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKL-PEFVDHARE 123
+ K LPV+RKDF+ +I + G +LLI L D L E A+
Sbjct: 105 ADAYLKEARAACALPVIRKDFMIDPYQIVEARAIGADCILLIVSALDDVLMAELAATAKS 164
Query: 124 HGLDTLVEVHTLEELKIAIQTNST-MIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVK 182
GLD LVEVH EL+ A++T T ++GINNR++ E+ ++ T L P IP +
Sbjct: 165 VGLDVLVEVHDGTELERALKTLDTPLVGINNRNLHTFEV---SLETTLDLLPEIPRDRLV 221
Query: 183 VSESGITTLEDLK-VALKYADAALIGTALMKTEDPEKLLK 221
V+ESGI D++ + + A L+G A M+ +DP LK
Sbjct: 222 VTESGILNRADVELMEVSEVYAFLVGEAFMRADDPGLELK 261
>sp|O06129|TRPC_MYCTU INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|7436781|pir||A70557
probable trpC protein - Mycobacterium tuberculosis
(strain H37RV) >gi|2113895|emb|CAB08905.1| (Z95554) trpC
[Mycobacterium tuberculosis]
Length = 272
Score = 114 bits (282), Expect = 1e-24
Identities = 69/211 (32%), Positives = 112/211 (52%), Gaps = 5/211 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G L DP ++ + Y+ GA +S +T+ + F+G+ D +
Sbjct: 54 VIAEVKRASPSAGALATIADPAKLAQAYQDGGARIVSVVTEQRRFQGSLDDLDAVRASVS 113
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVEVHTLE 136
+PVLRKDF+ +I + G +LLI L+ L +D G+ LVEVHT +
Sbjct: 114 IPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMTALVEVHTEQ 173
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGIT-TLEDLK 195
E A++ + +IG+N RD+ L++D A++AP +P ++++ESG+ T + L
Sbjct: 174 EADRALKAGAKVIGVNARDLMTLDVDR---DCFARIAPGLPSSVIRIAESGVRGTADLLA 230
Query: 196 VALKYADAALIGTALMKTEDPEKLLKSFVEA 226
A ADA L+G L+ + DP + V A
Sbjct: 231 YAGAGADAVLVGEGLVTSGDPRAAVADLVTA 261
>sp|Q9X7C7|TRPC_MYCLE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)
>gi|11268619|pir||T45256 probable
indole-3-glycerol-phosphate synthase (EC 4.1.1.48)
[imported] - Mycobacterium leprae
>gi|4883462|emb|CAB43179.1| (AL049913) putative
indole-3-glycerol phosphate synthase [Mycobacterium
leprae]
Length = 272
Score = 113 bits (279), Expect = 2e-24
Identities = 72/211 (34%), Positives = 110/211 (52%), Gaps = 5/211 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G L DP ++ + YE GA IS +T+ + F G+ D +
Sbjct: 54 VIAEVKRASPSVGSLATIADPAKLAQAYEDGGARIISVLTEERRFNGSLDDLDAVRAAVS 113
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHAREHGLDTLVEVHTLE 136
+PVLRKDF+ +I + G +LLI L + L +D G+ LVEV T +
Sbjct: 114 VPVLRKDFVVQPYQIHEARAHGADMLLLIVAALDQSALMSMLDRTESLGMIALVEVRTEQ 173
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLED-LK 195
E A++ + +IG+N RD+ LE+D S ++AP +P ++++ESG+ D L
Sbjct: 174 EADRALKAGAKVIGVNARDLMTLEVDRDCFS---RIAPGLPSNVIRIAESGVRGPADLLA 230
Query: 196 VALKYADAALIGTALMKTEDPEKLLKSFVEA 226
A ADA L+G L+K+ DP + V A
Sbjct: 231 YAGAGADAVLVGEGLVKSGDPRAAVADLVTA 261
>sp|O25867|TRPC_HELPY TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|7436776|pir||G64679 anthranilate isomerase -
Helicobacter pylori (strain 26695)
>gi|2314446|gb|AAD08324.1| (AE000632) anthranilate
isomerase (trpC) [Helicobacter pylori 26695]
Length = 452
Score = 112 bits (277), Expect = 4e-24
Identities = 73/218 (33%), Positives = 118/218 (53%), Gaps = 7/218 (3%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
K I E K SP G + + D L+I + YE+ + IS + D KYF G+++ K + +
Sbjct: 44 KTSFILECKKASPSKGLIRKDFDLLKITKTYEKFASC-ISVLADSKYFLGSYENIKIVSQ 102
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVEVH 133
+ P+L KDFI +I+ G +AVLL+ +L DK E + A+ + L EV
Sbjct: 103 HSTKPILCKDFIIDAFQIKLARMMGANAVLLMLSVLDDKNYLELFNLAKSLNMSVLTEVS 162
Query: 134 TLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLED 193
+E++ ++ +IGINNRD+ L+ D ++ T KL PL+P + +SESGI +
Sbjct: 163 NQQEIEHLLKLQYDIIGINNRDLHTLKTD---INHTLKLRPLLPKDALIISESGIYSHAQ 219
Query: 194 LKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
+K Y + L+G++LMK +D +K + E K+C
Sbjct: 220 IKALAPYVNGFLVGSSLMKEKDLKKACIKLILGENKVC 257
>sp|P94327|TRPC_BRAJA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)
>gi|11268629|pir||T46959 indole-3-glycerol-phosphate
synthase (EC 4.1.1.48) [imported] - Bradyrhizobium
japonicum >gi|1743889|gb|AAB39010.1| (U79771)
indole-3-glycerol-phosphate synthase [Bradyrhizobium
japonicum]
Length = 273
Score = 111 bits (276), Expect = 5e-24
Identities = 76/216 (35%), Positives = 109/216 (50%), Gaps = 8/216 (3%)
Query: 5 GLSRRIKRCTKN---PIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKY 61
G R IK N +IAE+K SP G + DP + + YE GA +S +TD
Sbjct: 40 GFLRAIKAKHTNGDFALIAEVKKASPSKGLIRADFDPPQFAKAYEAGGAACLSVLTDTPS 99
Query: 62 FRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDH 120
F+G+ DF T LPVLRKDF+ ++ + G +L+I L D + D
Sbjct: 100 FQGHLDFMVAARAATSLPVLRKDFMFDAYQVVEARAHGADCILIIMTALDDATAKDLEDT 159
Query: 121 AREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKF 180
A G+D L+E+H EL A++ S MIG+NNR++ E ++ + LAPLIP
Sbjct: 160 AIAFGMDVLIEIHDRAELDRALKLRSPMIGVNNRNLRTFET---TLATSEALAPLIPGDR 216
Query: 181 VKVSESGITTLEDL-KVALKYADAALIGTALMKTED 215
+ V ESGI T DL ++ L+G +LM+ D
Sbjct: 217 LMVGESGIFTPADLARLERVGMSTFLVGESLMRQAD 252
>sp|Q92370|TRPG_SCHPO ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|11268600|pir||T46566 anthranilate synthase
(EC 4.1.3.27), trifunctional - fission yeast
(Schizosaccharomyces pombe) >gi|1666213|emb|CAA70348.1|
(Y09137) trifunctional enzyme (trpG-trpC-trpF)
[Schizosaccharomyces pombe]
Length = 759
Score = 109 bits (271), Expect = 2e-23
Identities = 73/215 (33%), Positives = 122/215 (55%), Gaps = 11/215 (5%)
Query: 9 RIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFD- 67
R+K+ +K ++AE+K SP GD+ + Y + GA IS +T+PK+F+G+ +
Sbjct: 301 RLKQ-SKPALMAEVKRASPSKGDIKLDANAAIQALTYAQVGASVISVLTEPKWFKGSLND 359
Query: 68 -FFKRLCKE---TELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHAR 122
F R E +LRKDFI EI + G +VLLI +L +++L ++
Sbjct: 360 LFVARKAVEHVANRPAILRKDFIIDPYEIMEARLNGADSVLLIVAMLSREQLESLYKFSK 419
Query: 123 EHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVK 182
G++ LVEV+ EE+K AI+ + +IG+NNR++ E+D +S T+KLA ++PD +
Sbjct: 420 SLGMEPLVEVNCAEEMKTAIELGAKVIGVNNRNLHSFEVD---LSTTSKLAEMVPDDVIL 476
Query: 183 VSESGITTLEDL-KVALKYADAALIGTALMKTEDP 216
+ SGI++ D+ + + A L+G +LM+ DP
Sbjct: 477 AALSGISSPADVAHYSSQGVSAVLVGESLMRASDP 511
>sp|Q9Z4X0|TRC2_STRCO INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE 2 (IGPS)
>gi|7480774|pir||T36303 probable indoleglycerol
phosphate synthase - Streptomyces coelicolor
>gi|4490620|emb|CAB38582.1| (AL035654) putative
indoleglycerol phosphate synthase [Streptomyces
coelicolor A3(2)]
Length = 258
Score = 109 bits (269), Expect = 4e-23
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 7/210 (3%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G L P E+ R Y+ GA +S +T F G+ D E
Sbjct: 52 VIAEMKPRSPSKGPLTDDYRPAELARAYQGGGAHAVSVLTHEAGFGGSPDHLAVARAACE 111
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
LPVLRKDF+ + +I + G A+LLI L +L + R G++ LVEVH
Sbjct: 112 LPVLRKDFVVDEYQILEARALGADALLLIVAALAPARLAALLARTRACGMEALVEVHDER 171
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKV 196
E+ +A++ + +IG+N+RD+ +D +L+A+L + V V ESG+ D +
Sbjct: 172 EVDVALEAGADVIGVNHRDLRDFSIDR---TLSARLRGRVGTGRVMVGESGVRGAPDAR- 227
Query: 197 ALKYA--DAALIGTALMKTEDPEKLLKSFV 224
AL+ A DA L+G LM+ DP +K V
Sbjct: 228 ALEAAGVDAVLVGELLMRAGDPGTTIKGLV 257
>sp|P24773|TRPG_PENCH ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|320887|pir||S30084 anthranilate synthase
multifunctional enzyme - Penicillium chrysogenum
>gi|3164|emb|CAA28707.1| (X05033) trpC polypeptide (AA
1-752) [Penicillium chrysogenum]
Length = 752
Score = 108 bits (268), Expect = 5e-23
Identities = 72/205 (35%), Positives = 116/205 (56%), Gaps = 10/205 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + R Y +AGA IS +T+P++F+G D + + + E
Sbjct: 293 LMAEIKRASPSKGIISANVCAPAQAREYAKAGASVISVLTEPEWFKGTIDDLRAVRQSLE 352
Query: 78 -LP----VLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVE 131
LP VLRK+F+ + +I + AG VLLI ++L + L ++R G++ LVE
Sbjct: 353 GLPNRPAVLRKEFVFEEYQILEARLAGADTVLLIVKMLDIELLTRLYHYSRSLGMEPLVE 412
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+T EE+KIA+ S +IG+NNRD+ E+D G T++L +P+ + + SGI+
Sbjct: 413 VNTPEEMKIAVDLGSEVIGVNNRDLTSFEVDLGT---TSRLMDQVPESTIVCALSGISGP 469
Query: 192 EDLKVALKY-ADAALIGTALMKTED 215
+D++ K A L+G ALM+ D
Sbjct: 470 QDVEAYKKEGVKAILVGEALMRAPD 494
>pir||T39468 anthranilate synthase (EC 4.1.3.27) component II - fission yeast
(Schizosaccharomyces pombe) >gi|5579054|emb|CAB51341.1|
(AL096874) anthranilate synthase component II (EC
4.1.3.27) [Schizosaccharomyces pombe]
Length = 759
Score = 108 bits (268), Expect = 5e-23
Identities = 72/215 (33%), Positives = 122/215 (56%), Gaps = 11/215 (5%)
Query: 9 RIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFD- 67
R+K+ +K ++AE+K SP GD+ + Y + GA IS +T+PK+F+G+ +
Sbjct: 301 RLKQ-SKPALMAEVKRASPSKGDIKLDANAAIQALTYAQVGASVISVLTEPKWFKGSLND 359
Query: 68 -FFKRLCKE---TELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHAR 122
F R E +LRKDFI +I + G +VLLI +L +++L ++
Sbjct: 360 LFVARKAVEHVANRPAILRKDFIIDPYQIMEARLNGADSVLLIVAMLSREQLESLYKFSK 419
Query: 123 EHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVK 182
G++ LVEV+ EE+K AI+ + +IG+NNR++ E+D +S T+KLA ++PD +
Sbjct: 420 SLGMEPLVEVNCAEEMKTAIELGAKVIGVNNRNLHSFEVD---LSTTSKLAEMVPDDVIL 476
Query: 183 VSESGITTLEDL-KVALKYADAALIGTALMKTEDP 216
+ SGI++ D+ + + A L+G +LM+ DP
Sbjct: 477 AALSGISSPADVAHYSSQGVSAVLVGESLMRASDP 511
>sp|Q9XBM3|TRPC_ZYMMP INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS)
>gi|5566465|gb|AAD45395.1|AF167440_1 (AF167440)
indole-3-glycerol phosphate synthase [Zymomonas mobilis
subsp. pomaceae]
Length = 265
Score = 108 bits (267), Expect = 6e-23
Identities = 76/213 (35%), Positives = 115/213 (53%), Gaps = 12/213 (5%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + P YE GA +S +TD YF+G+ D+ K +
Sbjct: 56 LIAEIKKASPSKGLIRSDFTPAAHAHDYEEGGAACLSVLTDRPYFQGHEDYLIAARKAVK 115
Query: 78 LPV-LRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAR-EHGLDTLVEVHTL 135
LPV LRKDF+ ++ + G A+L+I L D+ + ++ A E+G+D LVEVH+
Sbjct: 116 LPVVLRKDFMIDPWQVTEARAIGADAILIIVAALDDQQMQDIEAAALEYGMDALVEVHSH 175
Query: 136 EELKIAIQTNSTMIGINNRDIGKLELDDGNVSL--TAKLAPLIPDKFVKVSESGITTLED 193
+E++ A++ S +IG+NNRD L D +VS T +L P V+ESGI +D
Sbjct: 176 DEMERALKLKSRLIGVNNRD-----LRDFSVSFDRTYELVGSAPKDCTFVAESGIPNHDD 230
Query: 194 LKVALKYADAA--LIGTALMKTEDPEKLLKSFV 224
L VA++ D L+G LM+ +D K K +
Sbjct: 231 L-VAMQRHDIGCFLVGETLMRQDDLRKATKDLL 262
>sp|Q9ZJU8|TRPC_HELPJ TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|7436775|pir||D71836 indole-3-glycerol phosphate
synthase - Helicobacter pylori (strain J99)
>gi|4155804|gb|AAD06779.1| (AE001546) INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE [Helicobacter pylori J99]
Length = 452
Score = 108 bits (266), Expect = 8e-23
Identities = 71/218 (32%), Positives = 116/218 (52%), Gaps = 7/218 (3%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
K I E K SP G + + D LEI + YE+ + +S + D KYF G+++ K + +
Sbjct: 44 KTSFILEYKKASPSKGLIRKDFDLLEITKTYEKFASC-VSVLADSKYFLGSYENIKIVSQ 102
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVEVH 133
+ P+L KDFI +I+ G +AVLL+ +L DK E + A+ + L EV
Sbjct: 103 HSTKPILCKDFIIDAFQIKLARVMGSNAVLLMLSVLDDKNYLELFNLAKSLNMSVLTEVS 162
Query: 134 TLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLED 193
+E++ ++ +IGINNRD+ L+ D + T +L PL+P + +SESGI +
Sbjct: 163 NQQEIERLLKLQYDIIGINNRDLHTLKTD---IFHTLELRPLLPKDAIIISESGIYSHAQ 219
Query: 194 LKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
+K + L+G++LMK +D +K + E K+C
Sbjct: 220 IKALAPCVNGFLVGSSLMKEKDLKKACIKLILGENKVC 257
>pir||F82232 indole-3-glycerol phosphate synthase/ phosphoribosylanthranilate
isomerase VC1171 [imported] - Vibrio cholerae (group O1
strain N16961) >gi|9655647|gb|AAF94330.1| (AE004197)
indole-3-glycerol phosphate
synthase/phosphoribosylanthranilate isomerase [Vibrio
cholerae]
Length = 469
Score = 108 bits (266), Expect = 8e-23
Identities = 73/214 (34%), Positives = 114/214 (53%), Gaps = 7/214 (3%)
Query: 19 IAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETEL 78
I E K SP G L+R L+ + A IS +TD KYF+G F+F ++ +
Sbjct: 66 ILECKKASPSKG-LIREEFDLDYIASVYGEYASAISVLTDEKYFQGRFEFLPQVRAQVAQ 124
Query: 79 PVLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVEVHTLEE 137
PVL KDF+ ++ A+LL+ +L D+ E A + G+ L EV +E
Sbjct: 125 PVLCKDFMVDPYQVYLARHYQADAILLMLSVLNDDQYRELAAVAHDLGMGVLTEVSNEQE 184
Query: 138 LKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKVA 197
LK A+ + +IGINNR++ L D ++ T +LAPLIP + +SESGI T + ++
Sbjct: 185 LKRAVDLQAKVIGINNRNLRDLTTD---LNRTKQLAPLIPQGTIIISESGIYTHQQVRDL 241
Query: 198 LKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++A+ LIG++LM + E ++ V E K+C
Sbjct: 242 AEFANGFLIGSSLMAQSNLELAVRKIVLGEHKVC 275
>sp|Q55508|TRPC_SYNY3 INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|7428356|pir||S76016
hypothetical protein - Synechocystis sp. (strain PCC
6803) >gi|1001373|dbj|BAA10863.1| (D64006)
indole-3-glycerol phosphate synthase [Synechocystis sp.]
Length = 295
Score = 107 bits (265), Expect = 1e-22
Identities = 73/208 (35%), Positives = 110/208 (52%), Gaps = 5/208 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + DP+ I + YE GA +S +TD K+F+G+F+ + + +
Sbjct: 81 LIAEVKKASPSKGIIRADFDPVAIAKAYEAGGANCLSVLTDEKFFQGSFENLQLVRSAVQ 140
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVEVHTLE 136
LP+L K+FI +I G AVLLI +L DK L F+ G+ LVEVHTLE
Sbjct: 141 LPLLCKEFIIYPYQIYLARSRGADAVLLIAAILSDKDLRYFLKIIEGLGMAALVEVHTLE 200
Query: 137 EL-KIAIQTNSTMIGINNRDIGKLELDDGNVS--LTAKLAPLIPDKFVKVSESGITTLED 193
E+ ++ +IG+NNR++ +D + L VSESGI L D
Sbjct: 201 EMDRVLALDGVQLIGVNNRNLQTFTVDLQTTEDLFAQRREQLTQGDITLVSESGIYELAD 260
Query: 194 L-KVALKYADAALIGTALMKTEDPEKLL 220
L ++ A A L+G +L+K DP++ +
Sbjct: 261 LQRLQQAGARAVLVGESLVKQPDPQQAI 288
>pir||H81216 indole-3-glycerol phosphate synthase NMB0275 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225500|gb|AAF40729.1| (AE002384) indole-3-glycerol
phosphate synthase [Neisseria meningitidis MC58]
Length = 260
Score = 107 bits (265), Expect = 1e-22
Identities = 72/202 (35%), Positives = 110/202 (53%), Gaps = 6/202 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + P EI R YE AGA +S +TD YF+G+ ++ K+ +
Sbjct: 56 VIAEIKKASPSKGLIRPDFRPAEIARAYENAGAACLSVLTDEPYFQGSPEYLKQAREAVS 115
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHAREHGLDTLVEVHTLE 136
LPVLRKDFI + ++ + G AVLLI L +++L F A E G+ L+E+H
Sbjct: 116 LPVLRKDFIIDEYQVYQARAWGADAVLLIAAALEQEQLERFEAVAHELGMTVLLELHDET 175
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK- 195
EL+ + + G+NNR++ E+ ++ T L P + K V V+ESGIT D++
Sbjct: 176 ELEKCRNLTTPLWGVNNRNLRTFEV---SLDQTLSLLPALEGKTV-VTESGITGKADVEF 231
Query: 196 VALKYADAALIGTALMKTEDPE 217
+ + LIG M+ +D E
Sbjct: 232 MQSRGVHTFLIGETFMRADDIE 253
>pir||G81794 indole-3-glycerol phosphate synthase (EC 4.1.1.48) NMA2212
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7380831|emb|CAB85423.1| (AL162758)
indole-3-glycerol phosphate synthase [Neisseria
meningitidis Z2491]
Length = 260
Score = 107 bits (265), Expect = 1e-22
Identities = 72/202 (35%), Positives = 110/202 (53%), Gaps = 6/202 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + P EI R YE AGA +S +TD YF+G+ ++ K+ +
Sbjct: 56 VIAEIKKASPSKGLIRPDFRPPEIARAYENAGAACLSVLTDEPYFQGSPEYLKQAREAVS 115
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHAREHGLDTLVEVHTLE 136
LPVLRKDFI + ++ + G AVLLI L +++L F A E G+ L+E+H
Sbjct: 116 LPVLRKDFIIDEYQVYQARAWGADAVLLIAAALEREQLERFEAVAHELGMTVLLELHDES 175
Query: 137 ELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK- 195
EL+ + + G+NNR++ E+ ++ T L P + K V V+ESGIT D++
Sbjct: 176 ELEKCRNLTTPLWGVNNRNLRTFEV---SLDQTLSLLPALEGKTV-VTESGITGKADVEF 231
Query: 196 VALKYADAALIGTALMKTEDPE 217
+ + LIG M+ +D E
Sbjct: 232 MQSRGVHTFLIGETFMRADDIE 253
>sp|P05328|TRPG_ASPNG ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|83656|pir||S00643 anthranilate synthase
multifunctional protein - Aspergillus niger
>gi|2421|emb|CAA30107.1| (X07071) trpC [Aspergillus
niger]
Length = 770
Score = 107 bits (264), Expect = 1e-22
Identities = 68/205 (33%), Positives = 115/205 (55%), Gaps = 10/205 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + R+Y +AGA IS +T+P++F+G+ D + + + E
Sbjct: 309 LMAEIKRASPSKGMIAENACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRQSLE 368
Query: 78 -----LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVE 131
+LRK+F+ + +I + AG VLLI ++L + L ++R G++ LVE
Sbjct: 369 GMTNRPAILRKEFVFDEYQILEARLAGADTVLLIVKMLSVELLTRLYHYSRSLGMEPLVE 428
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+T EE+KIA+ + +IG+NNRD+ E+D G T++L +P + + SGI+
Sbjct: 429 VNTPEEMKIAVDLGAEVIGVNNRDLTSFEVDLGT---TSRLMDQVPSSTIVCALSGISGP 485
Query: 192 EDLKVALKY-ADAALIGTALMKTED 215
+D++ K A L+G ALM+ D
Sbjct: 486 KDVEAYKKEGVKAILVGEALMRAAD 510
>pir||S11161 anthranilate synthase multifunctional protein - Aspergillus awamori
Length = 770
Score = 107 bits (264), Expect = 1e-22
Identities = 68/205 (33%), Positives = 115/205 (55%), Gaps = 10/205 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + R+Y +AGA IS +T+P++F+G+ D + + + E
Sbjct: 309 LMAEIKRASPSKGMIAENACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRQSLE 368
Query: 78 -----LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVE 131
+LRK+F+ + +I + AG VLLI ++L + L ++R G++ LVE
Sbjct: 369 GLTNRPAILRKEFVFDEYQILEARLAGADTVLLIVKMLSVELLTRLYHYSRSLGMEPLVE 428
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+T EE+KIA+ + +IG+NNRD+ E+D G T++L +P + + SGI+
Sbjct: 429 VNTPEEMKIAVDLGAEVIGVNNRDLTSFEVDLGT---TSRLMDQVPSSTIVCALSGISGP 485
Query: 192 EDLKVALKY-ADAALIGTALMKTED 215
+D++ K A L+G ALM+ D
Sbjct: 486 KDVEAYKKEGVKAILVGEALMRAAD 510
>sp|P18483|TRPG_ASPAW ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|1069996|emb|CAA37640.1| (X53576) trpC
polyprotein (AA 1-768) [Aspergillus niger]
Length = 768
Score = 107 bits (264), Expect = 1e-22
Identities = 68/205 (33%), Positives = 115/205 (55%), Gaps = 10/205 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + R+Y +AGA IS +T+P++F+G+ D + + + E
Sbjct: 307 LMAEIKRASPSKGMIAENACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRQSLE 366
Query: 78 -----LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLK-DKLPEFVDHAREHGLDTLVE 131
+LRK+F+ + +I + AG VLLI ++L + L ++R G++ LVE
Sbjct: 367 GLTNRPAILRKEFVFDEYQILEARLAGADTVLLIVKMLSVELLTRLYHYSRSLGMEPLVE 426
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+T EE+KIA+ + +IG+NNRD+ E+D G T++L +P + + SGI+
Sbjct: 427 VNTPEEMKIAVDLGAEVIGVNNRDLTSFEVDLGT---TSRLMDQVPSSTIVCALSGISGP 483
Query: 192 EDLKVALKY-ADAALIGTALMKTED 215
+D++ K A L+G ALM+ D
Sbjct: 484 KDVEAYKKEGVKAILVGEALMRAAD 508
>sp|O68427|TRPC_BUCDN TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|3170096|gb|AAC27734.1| (AF038565) phosphoribosyl
anthranilate isomerase/idoleglycerol phosphate
synthetase fusion [Buchnera aphidicola]
Length = 453
Score = 106 bits (263), Expect = 2e-22
Identities = 73/219 (33%), Positives = 117/219 (53%), Gaps = 8/219 (3%)
Query: 15 KNPI-IAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLC 73
KNP+ I E K SP G + + + ++I + Y + A IS +TD KYF G +F +
Sbjct: 47 KNPVFILECKKKSPSLGIIKKNFNLIDIAKIYNKY-ASAISVLTDEKYFDGKLEFINIVR 105
Query: 74 KETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEV 132
+ P+L KDF +I A+LL+ +L D + + A+E + L EV
Sbjct: 106 ERVSQPILCKDFFIDPFQIYLARYYNADAILLMLSILDDFQYQKLSKIAKELNMGILTEV 165
Query: 133 HTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLE 192
+ ELK AI+ N+ +IGINNR++ L + N++ T L+ LIP + +SESGIT +
Sbjct: 166 NNTSELKRAIKLNANIIGINNRNLHDLSI---NLNRTRILSSLIPKNIIIISESGITKYK 222
Query: 193 DLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ ++ + LIG+ LM + E ++S + E KIC
Sbjct: 223 QIRYLSQFVNGFLIGSHLMSEKQLEIGVRSLILGENKIC 261
>gb|AAA35176.1| (K01386) anthranilate synthase Component II:indole-3-glycerol
phosphate synthase (TRP3) [Saccharomyces cerevisiae]
Length = 484
Score = 106 bits (262), Expect = 2e-22
Identities = 70/218 (32%), Positives = 116/218 (53%), Gaps = 13/218 (5%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + E +Y AGA IS +T+P +F G+ + K +
Sbjct: 270 VLAEVKRASPSKGPICLKAVAAEQALKYAEAGASAISVLTEPHWFHGSLQDLVNVRKILD 329
Query: 78 LP--------VLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKL-PEFVDHAREHGLDT 128
L VLRK+FI +K +I + AG VLLI ++L L E ++++ ++
Sbjct: 330 LKFPPKERPCVLRKEFIFSKYQILEARLAGADTVLLIVKMLSQPLLKELYSYSKDLNMEP 389
Query: 129 LVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGI 188
LVEV++ EEL+ A++ + ++G+NNRD+ +D ++ T+ L IP + ++ SGI
Sbjct: 390 LVEVNSKEELQRALEIGAKVVGVNNRDLHSFNVD---LNTTSNLVESIPKDVLLIALSGI 446
Query: 189 TTLEDL-KVALKYADAALIGTALMKTEDPEKLLKSFVE 225
TT +D K + L+G ALMK+ D +K + E
Sbjct: 447 TTRDDAEKYKKEGVHGFLVGEALMKSTDVKKFIHELCE 484
>gi|6322638 anthranilate synthase Component II and indole-3-phosphate
(multifunctional enzyme); Trp3p [Saccharomyces
cerevisiae] >gi|549127|sp|P00937|TRPG_YEAST ANTHRANILATE
SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(PRAI)] >gi|538557|pir||NNBY2 anthranilate synthase
multifunctional enzyme - yeast (Saccharomyces
cerevisiae) >gi|473139|emb|CAA53562.1| (X75951) TRP3
[Saccharomyces cerevisiae] >gi|486377|emb|CAA82056.1|
(Z28211) ORF YKL211c [Saccharomyces cerevisiae]
Length = 484
Score = 106 bits (262), Expect = 2e-22
Identities = 70/218 (32%), Positives = 116/218 (53%), Gaps = 13/218 (5%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + E +Y AGA IS +T+P +F G+ + K +
Sbjct: 270 VLAEVKRASPSKGPICLKAVAAEQALKYAEAGASAISVLTEPHWFHGSLQDLVNVRKILD 329
Query: 78 LP--------VLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKL-PEFVDHAREHGLDT 128
L VLRK+FI +K +I + AG VLLI ++L L E ++++ ++
Sbjct: 330 LKFPPKERPCVLRKEFIFSKYQILEARLAGADTVLLIVKMLSQPLLKELYSYSKDLNMEP 389
Query: 129 LVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGI 188
LVEV++ EEL+ A++ + ++G+NNRD+ +D ++ T+ L IP + ++ SGI
Sbjct: 390 LVEVNSKEELQRALEIGAKVVGVNNRDLHSFNVD---LNTTSNLVESIPKDVLLIALSGI 446
Query: 189 TTLEDL-KVALKYADAALIGTALMKTEDPEKLLKSFVE 225
TT +D K + L+G ALMK+ D +K + E
Sbjct: 447 TTRDDAEKYKKEGVHGFLVGEALMKSTDVKKFIHELCE 484
>sp|P22098|TRPC_VIBPA TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|48489|emb|CAA35034.1| (X17149) indole-3- glycerol
phosphate synthase (trpC) [Vibrio parahaemolyticus]
Length = 481
Score = 105 bits (260), Expect = 4e-22
Identities = 77/222 (34%), Positives = 118/222 (52%), Gaps = 12/222 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
K I E K SP G L+R L+ + A IS +TD KYF+G+FDF ++ +
Sbjct: 71 KTVFITECKKASPSKG-LIRNDFDLDYIASVYNNYADAISVLTDEKYFQGSFDFLPQVRR 129
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREH-GLDTLVEVH 133
+ + PVL KDF+ ++ G AVLL+ +L D+ + ++ A + L EV
Sbjct: 130 QVKQPVLCKDFMVDTYQVYLARHYGADAVLLMLSVLNDEEYKALEEAAHSLNMGILTEVS 189
Query: 134 TLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAP----LIPDKFVKVSESGIT 189
EEL A+Q + +IGINNR++ L D ++ T LAP L P+ V +SESGI
Sbjct: 190 NEEELHRAVQLGAKVIGINNRNLRDLTTD---LNRTKALAPTIRKLAPNATV-ISESGIY 245
Query: 190 TLEDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
T + ++ +YAD LIG++LM ++ E ++ E K+C
Sbjct: 246 THQQVRDLAEYADGFLIGSSLMAEDNLELAVRKVTLGENKVC 287
>sp|P03964|TRPC_BACSU INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|1070512|pir||GWBS
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Bacillus subtilis >gi|143770|gb|AAA22867.1| (K01391)
TrpC protein [Bacillus subtilis]
>gi|2634684|emb|CAB14182.1| (Z99115) indol-3-glycerol
phosphate synthase [Bacillus subtilis]
>gi|224468|prf||1106178D protein trpC [Bacillus
subtilis]
Length = 250
Score = 104 bits (258), Expect = 7e-22
Identities = 71/206 (34%), Positives = 110/206 (52%), Gaps = 6/206 (2%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE+K SP G + P+ I + YE A +S +TD +F+G + + +
Sbjct: 42 LIAEVKKASPSKGLIKENFVPVRIAKDYETAKPDALSVLTDTPFFQGENSYLSDVKRAVS 101
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLE 136
+PVLRKDFI ++E++ G A+LLI +L L E A E +D LVEVH
Sbjct: 102 IPVLRKDFIIDSLQVEESRRIGADAILLIGEVLDPLHLHELYLEAGEKEMDVLVEVHDAT 161
Query: 137 ELKIAIQT-NSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
L+ ++ ++GINNR++ E +V T ++A L P + + VSESGI +LE L
Sbjct: 162 TLEQILKVFTPDILGINNRNLKTFET---SVKQTEQIASLAPKESLLVSESGIGSLEHLT 218
Query: 196 VALKY-ADAALIGTALMKTEDPEKLL 220
++ A A LIG +LM+ +K +
Sbjct: 219 FVKEHGARAVLIGESLMRQTSQQKAI 244
>sp|P57366|TRPC_BUCAI TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|10038954|dbj|BAB12989.1| (AP001118)
indole-3-glycerol phosphate synthase /
N-(5'-phospho-ribosyl)anthranilate isomerase [Buchnera
sp. APS]
Length = 453
Score = 102 bits (253), Expect = 3e-21
Identities = 70/214 (32%), Positives = 114/214 (52%), Gaps = 7/214 (3%)
Query: 19 IAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETEL 78
I E K SP G + + +EI Y++ A +S +TD KYF GN +F + +
Sbjct: 52 ILEYKKKSPSLGIIRNNFNLIEISNVYKKY-ASSVSVLTDEKYFHGNLNFINIVRECVSQ 110
Query: 79 PVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLEE 137
PVL KDF ++ + A+LL+ +L D + E A++ + L EV+ +EE
Sbjct: 111 PVLCKDFFIDPYQVYLSRYYNADAILLMLSVLNDIQYKELSIIAKKLNMGILTEVNNIEE 170
Query: 138 LKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKVA 197
LK A++ N+ +IGINNR++ L +D ++ T L+ LI + +SESGI ++K
Sbjct: 171 LKRALKLNANIIGINNRNLHDLSID---LNRTRTLSSLIKKDTIIISESGIKKYREIKEL 227
Query: 198 LKYADAALIGTALMKTEDPEKLLKS--FVEAKIC 229
K+ + LIG+ LM + E ++S F + K+C
Sbjct: 228 SKFVNGFLIGSHLMSQTNLETAVRSIIFGDNKVC 261
>sp|P00911|TRPC_ACICA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|68274|pir||GWKECC
indole-3-glycerol-phosphate synthase (EC 4.1.1.48) -
Acinetobacter calcoaceticus >gi|141802|gb|AAA21905.1|
(M36636) indole-glycerol phosphate synthase
[Acinetobacter calcoaceticus]
Length = 268
Score = 102 bits (252), Expect = 4e-21
Identities = 67/209 (32%), Positives = 117/209 (55%), Gaps = 7/209 (3%)
Query: 14 TKNP-IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRL 72
+K P +IAE+K SP G + +P EI ++YE+AGA +S +TD +F+G +
Sbjct: 51 SKRPGVIAEIKKASPSKGVIRVDFNPAEIAQQYEQAGAACLSVLTDVDFFQGADENIAIA 110
Query: 73 CKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVE 131
+ LP LRKDF+ + + +LLI L D +L E A E+ LD LVE
Sbjct: 111 RQHCSLPALRKDFLIDPYNVVEARALQADCILLIVACLSDQQLEEMSKTAFEYDLDVLVE 170
Query: 132 VHTLEELKIAIQ-TNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITT 190
VH +EL+ A++ + ++G+NNR++ ++D ++ + +L L+ + V+ESGI T
Sbjct: 171 VHDEQELERALKLSEQCLLGVNNRNLKTFDVD---LNTSLRLKKLLDPSRLLVTESGIAT 227
Query: 191 LEDLKVALKY-ADAALIGTALMKTEDPEK 218
+D+++ ++ + L+G + MK P++
Sbjct: 228 PQDVQLMQEHDIHSFLVGESFMKQPRPDQ 256
>sp|P42393|TRPC_BUCAP TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|625648|pir||B49897 indole-3-glycerol-phosphate
synthase (EC 4.1.1.48) / phosphoribosylanthranilate
isomerase (EC 5.3.1.24) - Buchnera aphidicola
>gi|396657|emb|CAA79499.1| (Z19055) phosphoribosyl
anthranilate isomerase/indoleglycerol phosphate
synthetase fusion [Buchnera aphidicola]
Length = 451
Score = 102 bits (251), Expect = 5e-21
Identities = 71/214 (33%), Positives = 114/214 (53%), Gaps = 8/214 (3%)
Query: 19 IAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETEL 78
I E K SP G + + + +EI Y+ A IS +TD KYF GN ++ + +
Sbjct: 52 ILECKKSSPSLGIIRKKFNLIEIANIYKNY-ASAISVLTDEKYFHGNIEYINVVRRCVSQ 110
Query: 79 PVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLEE 137
P+L KDF ++ A+LL+ +L D + E A+E + L E++ ++E
Sbjct: 111 PILCKDFFIDSYQVYLARYYSADAILLMLSVLNDSQYLELSRIAKELNMGVLTEINNIKE 170
Query: 138 LKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKVA 197
LK AI+ N+++IGINNR++ L +D ++ T L+PLI +K + VSESGI +K
Sbjct: 171 LKRAIKLNASVIGINNRNLHDLSID---LNRTRTLSPLIKNKII-VSESGIKKNHQIKEL 226
Query: 198 LKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
LIG++LM + E +KS + + K+C
Sbjct: 227 SNIVHGFLIGSSLMYRTNLETNIKSLIIGDNKVC 260
>gb|AAA65168.1| (U23496) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 102 bits (251), Expect = 5e-21
Identities = 73/218 (33%), Positives = 108/218 (49%), Gaps = 7/218 (3%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVICDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVH 133
P+L KDFI +I A LL+ +L D + + A + L EV
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLKMGVLTEVS 165
Query: 134 TLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLED 193
EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 166 NEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTYAQ 222
Query: 194 LKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +AD LIG+ALM +D ++ + E K+C
Sbjct: 223 VRELSHFADGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>sp|P06531|TRPG_EMENI ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|83695|pir||S04518 anthranilate synthase
multifunctional protein - Emericella nidulans
Length = 768
Score = 101 bits (250), Expect = 6e-21
Identities = 67/205 (32%), Positives = 115/205 (55%), Gaps = 10/205 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + R+Y +AGA IS +T+P++F+G+ D + + E
Sbjct: 306 LMAEIKRASPSKGLIAEHACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRASLE 365
Query: 78 -----LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKL-PEFVDHAREHGLDTLVE 131
+LRK+FI + +I + AG VLLI ++L +L +++ G++ LVE
Sbjct: 366 GLTNRPAILRKEFIFDEYQILEARLAGADTVLLIVKMLDTELLTRLYLYSQSLGMEPLVE 425
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+T +E+KIA+ + +IG+NNRD+ E+D G T++L +P+ + + SGI+
Sbjct: 426 VNTPDEMKIAVDLGAQVIGVNNRDLTSFEVDLGT---TSRLMDQVPESTIVCALSGISGP 482
Query: 192 EDLKVALK-YADAALIGTALMKTED 215
+D++ K A L+G ALM+ D
Sbjct: 483 KDVEAYKKDGVKAILVGEALMRAPD 507
>dbj|BAA97002.1| (AB023039) indole-3-glycerol phosphate synthase [Arabidopsis
thaliana]
Length = 379
Score = 101 bits (249), Expect = 8e-21
Identities = 73/212 (34%), Positives = 113/212 (52%), Gaps = 7/212 (3%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKE-T 76
+IAE+K SP G L +P+EI + YE+ GA +S +TD KYF+G+++ + + +
Sbjct: 160 LIAEVKKASPSRGILREDFNPVEIAQAYEKGGAACLSVLTDDKYFKGSYENLQAIMEAGV 219
Query: 77 ELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTL 135
+ P+L K+FI +I G AVLLI +L D + + + G+ TLVEVH
Sbjct: 220 KCPLLLKEFIVEAWQIYYGRSKGADAVLLIASVLPDLDIKYMIKICKILGMATLVEVHDE 279
Query: 136 EEL-KIAIQTNSTMIGINNRDIGKLELDDGNVS--LTAKLAPLIPDK-FVKVSESGITTL 191
E+ ++ +IGINNR++ E+D G L + LI K + V ESG+ T
Sbjct: 280 REMDRVLAIEGVELIGINNRNLETFEVDLGITKKLLEGERGELIRQKDILVVGESGLFTP 339
Query: 192 EDLK-VALKYADAALIGTALMKTEDPEKLLKS 222
ED+ V A L+G +L+K DP K + +
Sbjct: 340 EDIAFVQEAGVKAVLVGESLIKQSDPGKAIST 371
>gb|AAA73825.1| (U25423) anthranilate isomerase [Escherichia coli]
>gi|924825|gb|AAA73843.1| (U25427) anthranilate
isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>gb|AAA73831.1| (U25425) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>gb|AAA73837.1| (U25426) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVAVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>gb|AAA73855.1| (U25429) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>pir||T44526 indole-3-glycerol-phosphate synthase (EC 4.1.1.48) [imported] -
Nitrosomonas europaea >gi|5736649|dbj|BAA83387.1|
(AB030031) indoleglycerol phosphate synthase
[Nitrosomonas europaea]
Length = 306
Score = 101 bits (248), Expect = 1e-20
Identities = 79/248 (31%), Positives = 114/248 (45%), Gaps = 47/248 (18%)
Query: 18 IIAELKVYSPKYGDLLRGRD-------------------------PLEILRRYERAGAVG 52
+IAE+K SP G +LRGR P EI Y R GA
Sbjct: 56 VIAEIKRASPSKG-VLRGRSEAPNPQGSGHAENSSGKNLIPQDFIPAEIAASYARNGAAC 114
Query: 53 ISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-- 110
+S +TD ++F G+ DF ++ +LPVLRKDFI + ++ + G +LLI
Sbjct: 115 LSVLTDEQFFMGSADFLRQARAACDLPVLRKDFILDEYQVYEARAMGADCILLIVAAFLS 174
Query: 111 ----KDKLPEFVDHAREH-----------GLDTLVEVHTLEELKIAIQTNSTMIGINNRD 155
+D D A E G+ LVEVH +EL +A+Q + +IGINNR+
Sbjct: 175 PVFQQDASVNQGDSALERMRILETTAQALGMAILVEVHDADELDLALQLTTPLIGINNRN 234
Query: 156 IGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKVALK-YADAALIGTALMKTE 214
+ E + T +L IP + + V+ESGI D+++ L + A LIG M+
Sbjct: 235 LRTFET---TLDTTVQLVRRIPSERIVVTESGIRIPADVEMMLSHHIYAFLIGETFMRAP 291
Query: 215 DPEKLLKS 222
DP L S
Sbjct: 292 DPGAALAS 299
>gb|AAA65144.1| (U23491) anthranilate isomerase [Escherichia coli]
>gi|924776|gb|AAA73801.1| (U25419) anthranilate
isomerase [Escherichia coli] >gi|924783|gb|AAA73807.1|
(U25420) anthranilate isomerase [Escherichia coli]
>gi|924790|gb|AAA73813.1| (U25421) anthranilate
isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>gb|AAA65156.1| (U23493) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>pir||T47189 anthranilate isomerase [imported] - Escherichia coli
>gi|775159|gb|AAA65162.1| (U23494) anthranilate
isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVC 260
>gb|AAB60039.1| (U23495) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVC 260
>gb|AAB60044.1| (U23497) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>gb|AAB60050.1| (U23498) anthranilate isomerase [Escherichia coli]
>gi|1185399|gb|AAA87792.1| (U25884) anthranilate
isomerase [Escherichia coli] >gi|1185404|gb|AAA87796.1|
(U25885) anthranilate isomerase [Escherichia coli]
>gi|1185409|gb|AAA87800.1| (U25886) anthranilate
isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVC 260
>gb|AAA65174.1| (U23500) anthranilate isomerase [Escherichia coli]
>gi|924797|gb|AAA73819.1| (U25422) anthranilate
isomerase [Escherichia coli] >gi|924832|gb|AAA73849.1|
(U25428) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 101 bits (248), Expect = 1e-20
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>gb|AAB60054.1| (U23499) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 99.5 bits (244), Expect = 3e-20
Identities = 74/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLATVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EEL+ AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEELERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ + + LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFTNGFLIGSALMAHDDLNAAVRRVLLGENKVC 260
>gb|AAA65150.1| (U23492) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 98.7 bits (242), Expect = 5e-20
Identities = 74/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>gb|AAA73795.1| (U25418) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 98.7 bits (242), Expect = 5e-20
Identities = 74/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFDFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>emb|CAA23664.1| (V00366) reading frame trpC [Escherichia coli]
>gi|147957|gb|AAA57299.1| (J01714) anthranilate
isomerase [Escherichia coli]
Length = 452
Score = 98.3 bits (241), Expect = 7e-20
Identities = 74/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYFRG+F+F + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFRGSFNFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>emb|CAA23673.1| (V00372) trpC [Escherichia coli]
Length = 450
Score = 98.3 bits (241), Expect = 7e-20
Identities = 74/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYFRG+F+F + +
Sbjct: 46 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFRGSFNFLPIVSQ 104
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 105 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 162
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 163 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 219
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 220 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 259
>sp|P00909|TRPC_ECOLI TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
Length = 452
Score = 98.3 bits (241), Expect = 7e-20
Identities = 74/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYFRG+F+F + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFRGSFNFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>sp|P49572|TRPC_ARATH INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE PRECURSOR (IGPS)
>gi|619732|gb|AAA60380.1| (U18770) indole-3-glycerol
phosphate synthase [Arabidopsis thaliana]
Length = 368
Score = 98.3 bits (241), Expect = 7e-20
Identities = 71/213 (33%), Positives = 110/213 (51%), Gaps = 15/213 (7%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRL-CKET 76
+IAE+K SP G L DP+EI + YE+ GA +S +TD KYF+G F+ + +
Sbjct: 146 LIAEVKKASPSRGILKENFDPVEIAQAYEKGGAACLSVLTDQKYFQGGFENLEAIRSAGV 205
Query: 77 ELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTL 135
+ P+L K+F+ +I G AVLLI +L D ++ + ++ L LVEVH
Sbjct: 206 KCPLLCKEFVVDPWQIYYARTKGADAVLLIAAVLADLEITFLLKICKKLSLAALVEVHDE 265
Query: 136 EEL-KIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPD--------KFVKVSES 186
E+ ++ ++GINNR + E+D +S T KL L + + V ES
Sbjct: 266 REMGRVLGIEGIELVGINNRSLETFEVD---ISNTKKLLALEGEHGRQIRERDMIVVGES 322
Query: 187 GITTLEDLK-VALKYADAALIGTALMKTEDPEK 218
G+ T +D+ V A L+G +++K DPEK
Sbjct: 323 GLFTPDDIAYVQAAGVKAVLVGESIVKQNDPEK 355
>gb|AAD25838.1|AC006951_17 (AC006951) putative indole-3-glycerol phosphate synthase
[Arabidopsis thaliana]
Length = 402
Score = 97.9 bits (240), Expect = 9e-20
Identities = 69/208 (33%), Positives = 109/208 (52%), Gaps = 7/208 (3%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRL-CKET 76
+IAE+K SP G L DP+EI + YE+ GA +S +TD KYF+G F+ + +
Sbjct: 182 LIAEVKKASPSRGILKENFDPVEIAQAYEKGGAACLSVLTDQKYFQGGFENLEAIRSAGV 241
Query: 77 ELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTL 135
+ P+L K+F+ +I G AVLLI +L D ++ + ++ L LVEVH
Sbjct: 242 KCPLLCKEFVVDPWQIYYARTKGADAVLLIAAVLADLEITFLLKICKKLSLAALVEVHDE 301
Query: 136 EEL-KIAIQTNSTMIGINNRDIGKLELDDGNVS--LTAKLAPLIPDK-FVKVSESGITTL 191
E+ ++ ++GINNR + E+D N L + I ++ + V ESG+ T
Sbjct: 302 REMGRVLGIEGIELVGINNRSLETFEVDISNTKKLLEGEHGRQIRERDMIVVGESGLFTP 361
Query: 192 EDLK-VALKYADAALIGTALMKTEDPEK 218
+D+ V A L+G +++K DPEK
Sbjct: 362 DDIAYVQAAGVKAVLVGESIVKQNDPEK 389
>sp|P00910|TRPC_SALTY TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|68273|pir||GWEBT indole-3-glycerol-phosphate
synthase (EC 4.1.1.48) / phosphoribosylanthranilate
isomerase (EC 5.3.1.24) - Salmonella typhimurium
>gi|154397|gb|AAA27237.1| (M30286)
N-(5'-phosphoribosyl)-anthranilic acid
isomerase/indole-3-glycerol phosphate synthetase
[Salmonella typhimurium]
Length = 452
Score = 97.5 bits (239), Expect = 1e-19
Identities = 73/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+FDF + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIASIYQHY-ASAISVLTDEKYFQGSFDFLPVVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ + G+ L E
Sbjct: 106 SAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLSAVAHSLKMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNDEERERAIALGAKVVGINNRDLRDLSID---LNRTRQLAPKLGHGVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 GQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVC 260
>sp|P46451|TRPC_HAEIN TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|1574224|gb|AAC23036.1| (U32819) indole-3-glycerol
phosphate synthase / phosphoribosylanthranilate
isomerase (trpC) [Haemophilus influenzae Rd]
Length = 477
Score = 97.5 bits (239), Expect = 1e-19
Identities = 72/219 (32%), Positives = 109/219 (48%), Gaps = 5/219 (2%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
K I E K SP G L+R LE + + A +S +TD KYF+GNF+F +
Sbjct: 62 KPAYILECKKASPSKG-LIRAEFNLEEIANVYKHYASAVSVLTDEKYFQGNFEFLPLVRD 120
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPE-FVDHAREHGLDTLVEVH 133
PVL KDF+ ++ ++ A+LL+ ++ D+ D A G+ L E
Sbjct: 121 IVSQPVLCKDFMISEYQVYLARYYQVDAILLMLSVVNDETYRVLADLAHSLGMGVLTETS 180
Query: 134 TLEELKIAIQTNSTMIGINNRDIGKLELD-DGNVSLTAKLAPLIPDKFVKVSESGITTLE 192
EE + A+ + +IG+NNR++ L +D + V LT K A IP +SESGI +
Sbjct: 181 NEEEFERALALGAKIIGVNNRNLHDLTVDLNRVVELTKKYADCIPADVRIISESGIYNHK 240
Query: 193 DLKVALKYADAALIGTALMKTEDPEKLLKS--FVEAKIC 229
+ K A LIG++LM +D ++S F E K+C
Sbjct: 241 QIHQLQKVAHGFLIGSSLMGNQDLNNAVRSVIFGENKVC 279
>gb|AAF14253.1|AF132318_3 (AF132318) phosphoribosyl anthranilate isomerase/indoleglycerol
phosphate synthetase fusion [Buchnera aphidicola]
Length = 461
Score = 97.5 bits (239), Expect = 1e-19
Identities = 72/216 (33%), Positives = 105/216 (48%), Gaps = 9/216 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK-ET 76
+I E K SP G +L P + Y++ +V IS +TD KYF G F+F +
Sbjct: 52 LILEFKKSSPSLG-ILNNFKPEFVANIYKKYASV-ISVLTDEKYFGGKFEFIPIIRNIAV 109
Query: 77 ELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDH-AREHGLDTLVEVHTL 135
P+L KDF +I A+LL+ +L D F++ A + L E++
Sbjct: 110 NQPILCKDFFIDPYQIYLARYYKADAILLMLSILNDSQYIFLEEIATSLNMGVLTEINNR 169
Query: 136 EELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
EEL AI N+ +IGINNR++ L L ++S T KLAP IP +SESGI L+
Sbjct: 170 EELNRAIILNARVIGINNRNLHNLSL---SISNTHKLAPSIPKNITVISESGIKNYHQLR 226
Query: 196 VALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
LIG+ LM +D + ++ + KIC
Sbjct: 227 ELTSIVQGFLIGSVLMTKKDLDNTVRKIIMGNNKIC 262
>pdb|1PII| N-(5'phosphoribosyl)anthranilate Isomerase (E.C.5.3.1.24) Complex
With Indole-3-Glycerol-Phosphate Synthase (E.C.4.1.1.48)
>gi|1742051|dbj|BAA14794.1| (D90763)
Indole-3-glycerol-phosphate synthase (EC 4.1.1.48) /
phosphoribosylanthranilate isomerase (EC 5.3.1.24)
[Escherichia coli] >gi|1742055|dbj|BAA14797.1| (D90764)
Indole-3-glycerol-phosphate synthase (EC 4.1.1.48) /
phosphoribosylanthranilate isomerase (EC 5.3.1.24)
[Escherichia coli]
Length = 452
Score = 96.7 bits (237), Expect = 2e-19
Identities = 73/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+F+F + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFNFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>pir||I54118 anthranilate isomerase - Escherichia coli >gi|775124|gb|AAB60033.1|
(U23489) anthranilate isomerase [Escherichia coli]
>gi|775131|gb|AAA65138.1| (U23490) anthranilate
isomerase [Escherichia coli] >gi|924762|gb|AAA73789.1|
(U25417) anthranilate isomerase [Escherichia coli]
Length = 452
Score = 96.7 bits (237), Expect = 2e-19
Identities = 73/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+F+F + +
Sbjct: 47 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFNFLPIVSQ 105
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 106 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 163
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 164 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 220
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 221 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 260
>pir||GWEC indole-3-glycerol-phosphate synthase (EC 4.1.1.48) /
phosphoribosylanthranilate isomerase (EC 5.3.1.24) -
Escherichia coli >gi|1787516|gb|AAC74344.1| (AE000224)
N-(5-phosphoribosyl)anthranilate isomerase and
indole-3-glycerolphosphate synthetase [Escherichia coli
K12]
Length = 453
Score = 96.7 bits (237), Expect = 2e-19
Identities = 73/220 (33%), Positives = 110/220 (49%), Gaps = 11/220 (5%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
+ I E K SP G + DP I Y+ A IS +TD KYF+G+F+F + +
Sbjct: 48 RTAFILECKKASPSKGVIRDDFDPARIAAIYKHY-ASAISVLTDEKYFQGSFNFLPIVSQ 106
Query: 75 ETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD---KLPEFVDHAREHGLDTLVE 131
P+L KDFI +I A LL+ +L D + V H+ E G+ L E
Sbjct: 107 IAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV--LTE 164
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE + AI + ++GINNRD+ L +D ++ T +LAP + +SESGI T
Sbjct: 165 VSNEEEQERAIALGAKVVGINNRDLRDLSID---LNRTRELAPKLGHNVTVISESGINTY 221
Query: 192 EDLKVALKYADAALIGTALMKTEDPEKLLKSFV--EAKIC 229
++ +A+ LIG+ALM +D ++ + E K+C
Sbjct: 222 AQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVC 261
>sp|Q92411|TRPG_COCHE ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|1655574|emb|CAA49629.1| (X70035)
anthranilate synthase [Cochliobolus heterostrophus]
Length = 768
Score = 96.3 bits (236), Expect = 3e-19
Identities = 64/217 (29%), Positives = 119/217 (54%), Gaps = 10/217 (4%)
Query: 15 KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK 74
K +++E+K SP G + R Y +AGA IS +T+P++F+G+ + + + +
Sbjct: 307 KLSLMSEIKRASPSKGIISLSTCAPAQARLYAKAGARPISVLTEPEWFKGSIEDLRAVRQ 366
Query: 75 ETE-----LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPE-FVDHAREHGLDT 128
E +LRK+FI + +I + AG VL+I ++L+ +L E + + G++
Sbjct: 367 SIEGMANRPALLRKEFIFDEYQILEGRLAGADTVLVIVKMLETELLERLLGLSDSVGMEP 426
Query: 129 LVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGI 188
LVEV +E+KIA++ + +IG+NNR++ E+D G T +L ++P + + + SGI
Sbjct: 427 LVEVQNTDEMKIAVKLGAQVIGVNNRNLVNFEVDIGT---TNRLIQMVPKETILCALSGI 483
Query: 189 TTLEDLKVALK-YADAALIGTALMKTEDPEKLLKSFV 224
+D++ +K A L+G ALM+ D + + +
Sbjct: 484 AGPKDVEAYIKDGVGAVLVGEALMRASDMSQFISELL 520
>sp|P24920|TRPC_PHYPR TRYPTOPHAN BIOSYNTHESIS PROTEIN TRP1 [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|169310|gb|AAA33751.1| (M64473)
N-(5'-phosphoribosyl)anthranilate isomerase
indole-3-glycerol-phosphate synthase [Phytophthora
parasitica]
Length = 531
Score = 96.0 bits (235), Expect = 4e-19
Identities = 68/217 (31%), Positives = 112/217 (51%), Gaps = 18/217 (8%)
Query: 24 VYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE-----L 78
VY P L R P E ++ Y AGA IS +T+PK+F+G+ D + E
Sbjct: 38 VYGPALPVLERLNAPAEQVQAYANAGASMISVLTEPKWFKGSLDDMMEAREVVEGMSQRP 97
Query: 79 PVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHAREHGLDTLVEVHTLEE 137
+LRKDFI ++ + G VLLI LL K++L E +D G+ LVEV++++E
Sbjct: 98 AILRKDFIIDVYQLLEARAYGADCVLLIVTLLSKEQLIELIDATHNLGMCALVEVNSVQE 157
Query: 138 LKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGI-----TTLE 192
L IA+ + +IG+NNRD+ ++D ++ TA++A I ++ + + G+ + +
Sbjct: 158 LDIALAAKARLIGVNNRDLRTFKVD---MNTTARVADAIRERGLSLGRDGVALFALSGIR 214
Query: 193 DLKVALKY----ADAALIGTALMKTEDPEKLLKSFVE 225
+KY A L+G LMK+ D +K ++
Sbjct: 215 SHTDVVKYEKCGARGILVGEYLMKSGDIATTVKDLLQ 251
>sp|P25170|TRPG_PHACH ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|101928|pir||S15239 anthranilate synthase
multifunctional enzyme - basidiomycete (Phanerochaete
chrysosporium) >gi|3166|emb|CAA39518.1| (X56047) TrpC
[Phanerochaete chrysosporium]
Length = 788
Score = 94.8 bits (232), Expect = 8e-19
Identities = 67/226 (29%), Positives = 122/226 (53%), Gaps = 14/226 (6%)
Query: 9 RIKRCTKNP-IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFD 67
R+K P ++AE+K SP G + + + Y AGA IS +T+P +F+G+
Sbjct: 282 RLKAAEVKPALMAEVKRASPSKGPIAMNGNAAQQALTYALAGASVISVLTEPTWFKGSL- 340
Query: 68 FFKRLCKET--ELP----VLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDH 120
RL ++ LP +LRKDFI + +I++ G VLLI L +K L E +
Sbjct: 341 LDMRLARQAIDNLPHRPAILRKDFIIDEYQIDEARLHGADTVLLIVATLTEKRLEELYAY 400
Query: 121 AREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDK- 179
++ G++ LVEV+ +E++IA++ + +IG+NNR++ +D G T++LA ++ ++
Sbjct: 401 SQSLGMEPLVEVNNAKEMEIALKLGAKVIGVNNRNLHDFNVDMGT---TSRLAEMVRERD 457
Query: 180 FVKVSESGITTLEDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
+ + SGI +D+ ++ A L+G +LM+ D ++ +
Sbjct: 458 VILCALSGIKDAQDVNTYVEQGVGAVLVGESLMRAPDTRAFIRQLL 503
>sp|P00908|TRPG_NEUCR ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|68271|pir||NNNC2 anthranilate synthase (EC
4.1.3.27) component II - Neurospora crassa
Length = 762
Score = 93.6 bits (229), Expect = 2e-18
Identities = 66/211 (31%), Positives = 111/211 (52%), Gaps = 10/211 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+ AE+K SP G D R+Y AG IS +T+P++F+G+ D + + +
Sbjct: 305 LCAEIKRASPSKGVFALDIDAPSQARKYALAGGSVISVLTEPEWFKGSIDDLRAVRQVLN 364
Query: 78 -LP----VLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPE-FVDHAREHGLDTLVE 131
+P VLRK+FI + +I + AG VLLI ++L+ +L E ++ G++ LVE
Sbjct: 365 GMPNRPAVLRKEFIFDEYQILEARLAGADTVLLIVKMLEYELLERLYKYSLSLGMEPLVE 424
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V EE+ AI+ + +IG+NNR++ E+D G T +L ++P + SGI T
Sbjct: 425 VQNTEEMATAIKLGAKVIGVNNRNLESFEVDLGT---TGRLRSMVPSDTFLCALSGINTH 481
Query: 192 ED-LKVALKYADAALIGTALMKTEDPEKLLK 221
+D L + L+G A+M+ D + ++
Sbjct: 482 QDVLDCKRDGVNGILVGEAIMRAPDATQFVR 512
>sp|P06560|TRPC_BRELA TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|80603|pir||E24723 trpC protein - Corynebacterium
glutamicum >gi|39596|emb|CAA28626.1| (X04960) trpC (AA
1-474) [Corynebacterium glutamicum]
Length = 474
Score = 92.1 bits (225), Expect = 5e-18
Identities = 67/214 (31%), Positives = 105/214 (48%), Gaps = 7/214 (3%)
Query: 19 IAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETEL 78
I E K SP G + P EI R Y R A IS + +P F G++D + + L
Sbjct: 57 IMECKSASPSLGMIREHYQPGEIARVYSRYAAA-ISVLCEPDRFGGDYDHLATVGATSHL 115
Query: 79 PVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD-KLPEFVDHAREHGLDTLVEVHTLEE 137
PVL KDFI ++ G A+LL+ +L D + A LD L EV EE
Sbjct: 116 PVLCKDFIIDPVQVRPARYFGADAILLMLSVLDDEEYDALAAEAARFDLDILTEVIDEEE 175
Query: 138 LKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKVA 197
+ AI+ + + G+N+R++ L +D + + +L+ LIP V VSESG+ E ++
Sbjct: 176 VARAIKLGAKIFGVNHRNLHDLSID---LDRSRRLSKLIPADAVLVSESGVRDTETVRQL 232
Query: 198 LKYADAALIGTALMKTEDPEKLLKSFVEA--KIC 229
+++A L+G+ L E+ + + V K+C
Sbjct: 233 GGHSNAFLVGSQLTSQENVDLAARELVYGPNKVC 266
>dbj|BAB13482.1| (AB028647) TRP1 [Flammulina velutipes]
Length = 875
Score = 92.1 bits (225), Expect = 5e-18
Identities = 64/212 (30%), Positives = 114/212 (53%), Gaps = 11/212 (5%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNF-DFFKRLCKET 76
+IAE+K SP G + P Y +GA +S +T+PK+F G+ D
Sbjct: 303 LIAEVKRASPSKGPISLTTSPANQALTYALSGANAVSVLTEPKWFLGSLQDMLHARLSVG 362
Query: 77 ELP----VLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKL-PEFVDHAREHGLDTLVE 131
LP +LRKDFI ++ ++ ++ G +LLI +L + L + ++ E G++ LVE
Sbjct: 363 NLPNRPAILRKDFILSRYQVLESRIWGADTLLLIVAMLPEPLLRDLYKYSVELGMEPLVE 422
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKV-SESGITT 190
V+ ++E+++A+ N+ IGINNR++ ++D + T +L + V + + SGI+
Sbjct: 423 VNNVKEMELALSLNAKAIGINNRNLHDFKVD---MDTTTRLLDMAKGHDVVICALSGISN 479
Query: 191 LEDL-KVALKYADAALIGTALMKTEDPEKLLK 221
++ K A + A LIG +LM+ +DP ++
Sbjct: 480 ATEVNKYASQGVGAVLIGESLMRAKDPSAFIR 511
>sp|P20409|TRPG_PHYBL ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE
AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
(IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
(PRAI)] >gi|82774|pir||JT0383 anthranilate synthase (EC
4.1.3.27) component II - Phycomyces blakesleeanus
Length = 765
Score = 90.9 bits (222), Expect = 1e-17
Identities = 65/214 (30%), Positives = 115/214 (53%), Gaps = 14/214 (6%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G++ + E +Y AGA IS +T+PK+FRG+ + +++ +
Sbjct: 284 LMAEVKRASPSKGNIDITVNAAEQALQYALAGASVISVLTEPKWFRGSLNDLRQVREACP 343
Query: 78 LP-----VLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVE 131
L +LRK F+ +I + G VLLI ++ D+ L E ++ G++ LVE
Sbjct: 344 LLPNRPCILRKTFLLDTYQILEARLYGADTVLLIVAMMSDEDLRELYQYSVSLGMEPLVE 403
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+ EE+ A + +IG+NNR + ++D + T++LA ++P+ + + SGI+T
Sbjct: 404 VNNAEEMARANAVGAKLIGVNNRGLHSFDVD---METTSRLAEMVPEGTILCALSGISTR 460
Query: 192 EDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
D++ + L+G ALM+ + LK FV
Sbjct: 461 ADVETYVSQGVHGLLVGEALMRAWN----LKEFV 490
>gb|AAA33633.1| (M23177) trifunctional protein with glutamine amidotransferase
(TrpG), phosphoribosylanthranilate isomerase (TrpF), and
indoleglycerolphosphate synthetase (TrpC) activities
[Phycomyces blakesleeanus]
Length = 765
Score = 90.9 bits (222), Expect = 1e-17
Identities = 65/214 (30%), Positives = 115/214 (53%), Gaps = 14/214 (6%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G++ + E +Y AGA IS +T+PK+FRG+ + +++ +
Sbjct: 284 LMAEVKRASPSKGNIDITVNAAEQALQYALAGASVISVLTEPKWFRGSLNDLRQVREACP 343
Query: 78 LP-----VLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVE 131
L +LRK F+ +I + G VLLI ++ D+ L E ++ G++ LVE
Sbjct: 344 LLPNRPCILRKTFLLDTYQILEARLYGADTVLLIVAMMSDEDLRELYQYSVSLGMEPLVE 403
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+ EE+ A + +IG+NNR + ++D + T++LA ++P+ + + SGI+T
Sbjct: 404 VNNAEEMARANAVGAKLIGVNNRGLHSFDVD---METTSRLAEMVPEGTILCALSGISTR 460
Query: 192 EDLKVALKY-ADAALIGTALMKTEDPEKLLKSFV 224
D++ + L+G ALM+ + LK FV
Sbjct: 461 ADVETYVSQGVHGLLVGEALMRAWN----LKEFV 490
>pir||S07305 trpC protein - Emericella nidulans >gi|2423|emb|CAA26232.1|
(X02390) trpC polypeptide [Emericella nidulans]
Length = 768
Score = 90.5 bits (221), Expect = 2e-17
Identities = 61/205 (29%), Positives = 110/205 (52%), Gaps = 10/205 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
++AE+K SP G + R+Y +AGA IS +T+P++F+G+ D + + E
Sbjct: 306 LMAEIKRASPSKGLIAEHACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRASLE 365
Query: 78 -----LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKL-PEFVDHAREHGLDTLVE 131
+LRK+FI + +I + AG +I ++L +L + + + G++ LVE
Sbjct: 366 GLTNRPAILRKEFIFDEYQILEARLAGADTSYVIVKMLDTELLTQTLSLFQSLGMEPLVE 425
Query: 132 VHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTL 191
V+T +E+KIA+ + +IG+NNRD+ E+D G T++L +P+ +++
Sbjct: 426 VNTPDEMKIAVDLGAQVIGVNNRDLTSFEVDLGT---TSRLMDQVPESTIRLCTMRYFWT 482
Query: 192 EDLKVALK-YADAALIGTALMKTED 215
+D++ K A L+G ALM+ D
Sbjct: 483 KDVEAYKKDGVKAILVGEALMRAPD 507
>sp|Q44603|TRPC_BUCSC TRYPTOPHAN BIOSYNTHESIS PROTEIN TRPCF [INCLUDES: INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE (IGPS);
N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)]
>gi|769837|gb|AAA92795.1| (U09185) phosphoribosyl
anthranilate isomerase/indoleglycerol phosphate synthase
fusion [Buchnera aphidicola]
Length = 461
Score = 90.1 bits (220), Expect = 2e-17
Identities = 68/216 (31%), Positives = 104/216 (47%), Gaps = 9/216 (4%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCK-ET 76
+I E K +SP G +L +P + + Y++ A IS +TD KYF G F+F +
Sbjct: 52 LILEFKKHSPSLG-ILNDFNPEFVAKIYKKY-ASAISVLTDEKYFHGKFEFIPIIRNIAV 109
Query: 77 ELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDH-AREHGLDTLVEVHTL 135
+ P+L KDF +I ++LL+ +LKD ++ A + L E++
Sbjct: 110 QQPILCKDFFIDPYQIYLARYYQADSILLMLSILKDNQYRALEKLAYSLNMAVLTEINNK 169
Query: 136 EELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLK 195
EL AI N+ +IGINNR++ + N T KLA I + +SESGI + L+
Sbjct: 170 MELDRAINLNAKIIGINNRNLKNFSISTSN---TYKLASKISKNTIVISESGINSYNQLR 226
Query: 196 VALKYADAALIGTALMKTEDPEKLLKSFVEA--KIC 229
LIG+ALM +D E + + KIC
Sbjct: 227 KFKNLVQGFLIGSALMSKKDLEHAVHKIITGNNKIC 262
>emb|CAB37686.1| (AJ239573) anthranilate isomerase [Helicobacter pylori]
Length = 152
Score = 86.2 bits (210), Expect = 3e-16
Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 4/154 (2%)
Query: 53 ISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD 112
IS + D KYF G+++ K + + + P+L KDFI +I+ G +AVLL+ +L D
Sbjct: 2 ISVLADSKYFLGSYENIKMVSQHSTKPILCKDFIIDAFQIKLARMMGANAVLLMLSVLDD 61
Query: 113 K-LPEFVDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAK 171
K E + A+ + L EV +E+K ++ +IGINNRD+ L+ D + T K
Sbjct: 62 KNYLELFNLAKSLNMSVLTEVSNKQEIKRLLKLQYDIIGINNRDLHTLKTD---IDHTLK 118
Query: 172 LAPLIPDKFVKVSESGITTLEDLKVALKYADAAL 205
L PL+P + +SESGI + +K Y + L
Sbjct: 119 LRPLLPKDALIISESGIYSHAQIKALAPYVNGFL 152
>emb|CAB37682.1| (AJ239569) anthranilate isomerase [Helicobacter pylori]
Length = 152
Score = 85.8 bits (209), Expect = 4e-16
Identities = 55/154 (35%), Positives = 82/154 (52%), Gaps = 4/154 (2%)
Query: 53 ISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD 112
IS + D KYF G+++ K + + + PVL KDFI +I+ G +AVLL+ +L D
Sbjct: 2 ISVLADSKYFLGSYENIKIVSQHSTKPVLCKDFIIDAFQIKLARMMGANAVLLMLSVLDD 61
Query: 113 K-LPEFVDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAK 171
K + + A+ + L EV +E+K ++ +IGINNRD+ L D N T K
Sbjct: 62 KNYLKLFNLAKSLNMSVLTEVSNQQEIKRLLKLQYDIIGINNRDLHTLTTDINN---TLK 118
Query: 172 LAPLIPDKFVKVSESGITTLEDLKVALKYADAAL 205
L PL+P + VSESGI + +K Y + L
Sbjct: 119 LRPLLPKDVLVVSESGIHSHAQIKALAPYVNGFL 152
>emb|CAB37689.1| (AJ239576) anthranilate isomerase [Helicobacter pylori]
Length = 152
Score = 85.8 bits (209), Expect = 4e-16
Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 4/154 (2%)
Query: 53 ISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD 112
IS + D KYF G+++ K + + + P+L KDFI +I+ G +AVLL+ +L D
Sbjct: 2 ISVLADSKYFLGSYENIKMVAQHSIKPILCKDFIIDAFQIKLARMMGANAVLLMLSVLDD 61
Query: 113 K-LPEFVDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAK 171
K E + A+ + L EV +E+K ++ +IGINNRD+ L+ D + T K
Sbjct: 62 KNYLELFNLAKSLSMSVLTEVSNKQEIKRLLKLQYDIIGINNRDLHTLKTD---IDHTLK 118
Query: 172 LAPLIPDKFVKVSESGITTLEDLKVALKYADAAL 205
L PL+P + +SESGI + +K Y + L
Sbjct: 119 LRPLLPKDALIISESGIYSHAQIKALAPYVNGFL 152
>emb|CAB37685.1| (AJ239572) anthranilate isomerase [Helicobacter pylori]
Length = 152
Score = 85.4 bits (208), Expect = 5e-16
Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 4/154 (2%)
Query: 53 ISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD 112
IS + D KYF G+++ K + + + P+L KDFI +I+ G +AVLL+ +L D
Sbjct: 2 ISVLADSKYFLGSYENIKMVSQHSIKPILCKDFIIDAFQIKLARMMGANAVLLMLSVLDD 61
Query: 113 K-LPEFVDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAK 171
K E + A+ + L EV +E+K ++ +IGINNRD+ L+ D + T K
Sbjct: 62 KNYLELFNLAKSLNMSVLTEVSNQQEIKRLLKLQYDIIGINNRDLHTLKTD---IDHTLK 118
Query: 172 LAPLIPDKFVKVSESGITTLEDLKVALKYADAAL 205
L PL+P + +SESGI + +K Y + L
Sbjct: 119 LRPLLPKDALIISESGIYSHAQIKTLAPYVNGFL 152
>emb|CAB37688.1| (AJ239575) anthranilate isomerase [Helicobacter pylori]
Length = 152
Score = 85.4 bits (208), Expect = 5e-16
Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 4/154 (2%)
Query: 53 ISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD 112
IS + D KYF G+++ K + + + P+L KDFI +I+ G +AVLL+ +L D
Sbjct: 2 ISVLADSKYFLGSYENIKMVSQHSIKPILCKDFIIDAFQIKLARVMGANAVLLMLSVLDD 61
Query: 113 K-LPEFVDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAK 171
K E + A+ + L EV +E+K ++ +IGINNRD+ L+ D + T K
Sbjct: 62 KNYLELFNLAKSLNMSVLTEVSNQQEIKRLLKLQYDIIGINNRDLHTLKTD---IDHTLK 118
Query: 172 LAPLIPDKFVKVSESGITTLEDLKVALKYADAAL 205
L PL+P + +SESGI + +K Y + L
Sbjct: 119 LRPLLPKDALIISESGIYSHTQIKALAPYVNGFL 152
>emb|CAB37690.1| (AJ239577) anthranilate isomerase [Helicobacter pylori]
Length = 152
Score = 84.7 bits (206), Expect = 9e-16
Identities = 52/154 (33%), Positives = 84/154 (53%), Gaps = 4/154 (2%)
Query: 53 ISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKD 112
IS + D KYF G+++ K + + + P+L KDFI +I+ G +AVLL+ +L D
Sbjct: 2 ISVLADSKYFLGSYENIKIVSQHSTKPILCKDFIIDAFQIKLARMMGANAVLLMLSVLDD 61
Query: 113 K-LPEFVDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAK 171
K E + A+ + L EV +E+K ++ +IGINNRD+ L+ D ++ T +
Sbjct: 62 KNYLELFNLAKSLNMSVLTEVSNKQEIKRLLKLQYDIIGINNRDLHTLKTD---INHTLE 118
Query: 172 LAPLIPDKFVKVSESGITTLEDLKVALKYADAAL 205
L PL+P + +SESGI + +K Y + L
Sbjct: 119 LRPLLPKDALVISESGIYSHAQIKALAPYVNGFL 152
>sp|Q9Y8T7|TRPC_AERPE INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|7436780|pir||C72488
probable indole-3-glycerol phosphate synthase APE2546 -
Aeropyrum pernix (strain K1) >gi|5106252|dbj|BAA81563.1|
(AP000064) 261aa long hypothetical indole-3-glycerol
phosphate synthase [Aeropyrum pernix]
Length = 261
Score = 82.3 bits (200), Expect = 4e-15
Identities = 69/216 (31%), Positives = 109/216 (49%), Gaps = 15/216 (6%)
Query: 18 IIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETE 77
+IAE K SP G + DP+ ++ A A S +T+P +F G+ + +
Sbjct: 51 VIAEYKRCSPSAG-AISTLDPVSYVQATRDASAA-YSVLTEPNWFCGSIELIPYFARYK- 107
Query: 78 LPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDK-LPEFVDHAREHGLDTLVEV---- 132
PVL KDFI ++ +I A G SA LLI L + L E A +G++ LVE
Sbjct: 108 -PVLAKDFIVSETQIRIAACMGASAALLIMEALTPRELQELAAAASRYGVEVLVETPDAS 166
Query: 133 HTLEELKIAIQTNSTMIGINNRDIGKLELD-DGNVSLTAKLAPLIPDKFVKVSESGITTL 191
H +E ++A ++IG+N+RD+ L +D + + +K +P + + V+ESGI +
Sbjct: 167 HAVEASRLA---PGSIIGVNSRDLKTLRVDYEAMLREVSKAREQLPGEVILVAESGIDSP 223
Query: 192 EDLKVALKY-ADAALIGTALMKTED-PEKLLKSFVE 225
+ A K A A L+GTA MK EK+L ++
Sbjct: 224 DKALKAFKAGAQAILVGTAFMKNPQLREKILAELLQ 259
>sp|Q02584|TRPC_RHOCA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|282168|pir||A42948
indoleglycerol phosphate synthase, TrpC - Rhodobacter
capsulatus >gi|152043|gb|AAA26181.1| (M97640)
indoleglycerol phosphate synthase [Rhodobacter
capsulatus]
Length = 261
Score = 80.4 bits (195), Expect = 2e-14
Identities = 69/216 (31%), Positives = 107/216 (48%), Gaps = 10/216 (4%)
Query: 4 FGLSRRIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFR 63
FG + R K +IAE+K SP G + DP + R YE GA +S +TD F+
Sbjct: 41 FGQALRKKSAQGYGLIAEIKKASPSKGLIRPDFDP-PVARAYEDGGAACLSVLTDTPSFQ 99
Query: 64 GNFDFFKRLCKETELPV-LRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLP-EFVDHA 121
G D+ + + T P KDF+ ++ + G +L+I ++D L E A
Sbjct: 100 GAPDYL--IARGTPAPCPPSKDFLYDPYQVAEARAWGADCILIIMASVEDALAVELEAAA 157
Query: 122 REHGLDTLVEVHTLEELKIAIQ-TNSTMIGINNRDIGKLELDDGNVSLTAKLAPLI-PDK 179
G+D L+EVH EL A++ S ++G+NNR++ E+ + +T +AP+I +
Sbjct: 158 TGWGMDVLIEVHDGAELDRALKWLKSPLLGVNNRNLKTFEV---TLDVTRHVAPVILAEG 214
Query: 180 FVKVSESGITTLEDLKVALKYADAALIGTALMKTED 215
V ESGI T + +A A LIG +LM+ D
Sbjct: 215 RELVCESGIFTRDMAAMAAVGARRFLIGESLMRQAD 250
>emb|CAC11937.1| (AL445065) indole-3-glycerol-phosphate synthase related protein
[Thermoplasma acidophilum]
Length = 237
Score = 71.4 bits (172), Expect = 9e-12
Identities = 61/213 (28%), Positives = 97/213 (44%), Gaps = 17/213 (7%)
Query: 6 LSRRIKRCT---KNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYF 62
L R I+ C + +IAE K SP D L + G+S +++P +F
Sbjct: 26 LRRAIELCNGEGRRGLIAEYKRRSPS--GFSTDEDISSYLSYVKMHRIAGLSILSEPTHF 83
Query: 63 RGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLL-KDKLPEFVDHA 121
G+FD L +PVL KDF +E AGG AVL I L + + V +
Sbjct: 84 SGSFDDVT-LAHRIGVPVLVKDFAPDDHFVESAYNAGGDAVLAILDFLPSEDVERIVRRS 142
Query: 122 REHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFV 181
+ G+D + E H + LK + ++ ++G N RD+ VSL +P +
Sbjct: 143 ADLGMDVIEEYHDRKALKKFVDGDNVILGYNRRDL---------VSLKTGEDQDMPQYDI 193
Query: 182 KVSESGITTLEDLKVALKYADAALIGTALMKTE 214
+ ESGI + V ++Y+ LIGT+++K +
Sbjct: 194 TILESGINIDNVVHVDMRYS-GFLIGTSILKRD 225
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.140 0.388
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79516873
Number of Sequences: 2977
Number of extensions: 3207245
Number of successful extensions: 8836
Number of sequences better than 1.0e-10: 116
Number of HSP's better than 0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 8559
Number of HSP's gapped (non-prelim): 118
length of query: 229
length of database: 189,106,746
effective HSP length: 56
effective length of query: 173
effective length of database: 155,591,474
effective search space: 26917325002
effective search space used: 26917325002
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 163 (67.9 bits)