BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2045 (trpE) DE:anthranilate synthase component I (trpE)
(434 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75163 anthranilate synthase component I (trpe) PAB2045 - P... 866 0.0
sp|Q9YGB3|TRPE_PYRKO ANTHRANILATE SYNTHASE COMPONENT I >gi|11268... 633 e-180
gi|11499196 anthranilate synthase component I (trpE) {Methanococ... 406 e-112
sp|Q58475|TRPE_METJA ANTHRANILATE SYNTHASE COMPONENT I >gi|21277... 299 5e-80
sp|O27692|TRPE_METTH ANTHRANILATE SYNTHASE COMPONENT I >gi|74367... 298 6e-80
sp|P33975|TRPE_HALVO ANTHRANILATE SYNTHASE COMPONENT I >gi|99224... 297 2e-79
sp|Q08653|TRPE_THEMA ANTHRANILATE SYNTHASE COMPONENT I >gi|74367... 295 5e-79
pir||S34746 anthranilate synthase (EC 4.1.3.27) component I - Th... 295 7e-79
sp|P26940|TRPE_METTM ANTHRANILATE SYNTHASE COMPONENT I >gi|99101... 291 1e-77
sp|O66849|TRPE_AQUAE ANTHRANILATE SYNTHASE COMPONENT I >gi|74367... 289 3e-77
sp|P14953|TRPE_CLOTM ANTHRANILATE SYNTHASE COMPONENT I >gi|80536... 280 2e-74
dbj|BAB05378.1| (AP001512) anthranilate synthase [Bacillus halod... 276 3e-73
gb|AAG19902.1| (AE005074) anthranilate synthase alpha chain; Trp... 271 1e-71
sp|P23315|TRPE_ACICA ANTHRANILATE SYNTHASE COMPONENT I >gi|95307... 270 2e-71
pdb|1QDL|A Chain A, The Crystal Structure Of Anthranilate Syntha... 265 6e-70
gb|AAK41175.1| Anthranilate synthase component I (trpE) [Sulfolo... 265 6e-70
sp|P05378|TRPE_THETH ANTHRANILATE SYNTHASE COMPONENT I >gi|77582... 265 7e-70
sp|Q06128|TRPE_SULSO ANTHRANILATE SYNTHASE COMPONENT I >gi|42172... 263 2e-69
sp|Q9Z4W7|TRPE_STRCO ANTHRANILATE SYNTHASE COMPONENT I >gi|74804... 262 6e-69
sp|P20579|TRPE_PSEPU ANTHRANILATE SYNTHASE COMPONENT I >gi|94874... 261 8e-69
sp|Q9X6J4|TRPE_BACST ANTHRANILATE SYNTHASE COMPONENT I >gi|49289... 260 2e-68
sp|Q02001|TRPE_LACLA ANTHRANILATE SYNTHASE COMPONENT I >gi|42141... 259 4e-68
sp|P30526|TRPE_BACCA ANTHRANILATE SYNTHASE COMPONENT I >gi|47858... 259 6e-68
sp|P18267|TRPE_BACPU ANTHRANILATE SYNTHASE COMPONENT I 256 4e-67
pir||JH0098 anthranilate synthase (EC 4.1.3.27) component I - Ba... 256 4e-67
pir||T46852 anthranilate synthase (EC 4.1.3.27) component I [sim... 256 4e-67
sp|P20580|TRPE_PSEAE ANTHRANILATE SYNTHASE COMPONENT I >gi|94755... 256 5e-67
sp|P20463|TRPE_LEPBI ANTHRANILATE SYNTHASE COMPONENT I >gi|94610... 255 6e-67
pir||T01990 anthranilate synthase (EC 4.1.3.27) alpha-2 chain - ... 255 6e-67
sp|P95646|TRPE_RHOSH ANTHRANILATE SYNTHASE COMPONENT I >gi|18352... 255 8e-67
sp|P32069|TRPX_ARATH ANTHRANILATE SYNTHASE COMPONENT I-2 PRECURS... 254 1e-66
sp|Q9XAZ0|TRPE_NEIMA ANTHRANILATE SYNTHASE COMPONENT I >gi|11268... 254 2e-66
sp|P56995|TRPE_NEIMB ANTHRANILATE SYNTHASE COMPONENT I >gi|11268... 253 2e-66
pir||E75353 anthranilate synthase component I - Deinococcus radi... 252 4e-66
gb|AAA74900.1| (L34343) anthranilate synthase alpha subunit [Rut... 252 6e-66
pir||JQ1685 anthranilate synthase (EC 4.1.3.27) alpha-2 chain - ... 251 9e-66
pir||A82835 anthranilate synthase component I XF0210 [imported] ... 250 2e-65
pir||T35072 probable anthranilate synthase component I - Strepto... 250 3e-65
pir||A39128 anthranilate synthase (EC 4.1.3.27) component I [val... 249 5e-65
sp|Q9S358|TRPE_NEIMC ANTHRANILATE SYNTHASE COMPONENT I >gi|50514... 249 6e-65
sp|P21689|TRPE_PSESS ANTHRANILATE SYNTHASE COMPONENT I >gi|15162... 249 6e-65
sp|P96556|TRPE_ARTGO ANTHRANILATE SYNTHASE COMPONENT I >gi|18817... 249 6e-65
sp|Q9X7C5|TRPE_MYCLE ANTHRANILATE SYNTHASE COMPONENT I >gi|11268... 248 8e-65
sp|Q9WW00|TRPE_NEIGO ANTHRANILATE SYNTHASE COMPONENT I >gi|50514... 248 1e-64
dbj|BAA82094.1| (AB022602) anthranilate synthase alpha 1 subunit... 247 2e-64
sp|O06127|TRPE_MYCTU ANTHRANILATE SYNTHASE COMPONENT I >gi|74367... 247 2e-64
dbj|BAA02200.1| (D12706) anthranilate synthetase [Pseudomonas ae... 244 1e-63
sp|P03963|TRPE_BACSU ANTHRANILATE SYNTHASE COMPONENT I >gi|10705... 244 2e-63
gb|AAF76162.1|AF266751_1 (AF266751) anthranilate synthase large ... 243 4e-63
sp|P20170|TRPE_SYNY3 PROBABLE ANTHRANILATE SYNTHASE COMPONENT I ... 243 4e-63
sp|P28820|PABB_BACSU PARA-AMINOBENZOATE SYNTHASE COMPONENT I (AD... 241 1e-62
dbj|BAA82095.1| (AB022603) anthranilate synthase alpha 2 subunit... 239 5e-62
sp|P32068|TRPE_ARATH ANTHRANILATE SYNTHASE COMPONENT I-1 PRECURS... 238 7e-62
pir||JQ1684 anthranilate synthase (EC 4.1.3.27) alpha-1 chain - ... 238 7e-62
pir||T50834 anthranilate synthase (EC 4.1.3.27) alpha chain [imp... 237 2e-61
dbj|BAB03809.1| (AP001507) para-aminobenzoate synthase component... 237 2e-61
sp|P21690|TRPE_SPIAU ANTHRANILATE SYNTHASE COMPONENT I >gi|94597... 233 3e-60
pir||T40974 anthranilate synthase component i - fission yeast (... 219 5e-56
sp|Q9Y8T0|TRPE_AERPE ANTHRANILATE SYNTHASE COMPONENT I 219 5e-56
pir||T49199 anthranilate synthase alpha-1 chain-like protein - A... 217 2e-55
pir||B72489 probable anthranilate synthase component I APE2553 -... 216 4e-55
sp|P22099|TRPE_VIBPA ANTHRANILATE SYNTHASE COMPONENT I >gi|48486... 215 1e-54
gb|AAG28534.1|AF198621_5 (AF198621) p-aminobenzoate synthase [Ba... 213 2e-54
pir||B83427 para-aminobenzoate synthase component I PA1758 [impo... 212 5e-54
pir||A82233 anthranilate synthase component I VC1174 [imported] ... 212 7e-54
pir||T43181 probable anthranilate synthase (EC 4.1.3.27) chain I... 211 1e-53
sp|Q9ZER9|TRPE_BUCPS ANTHRANILATE SYNTHASE COMPONENT I >gi|41601... 210 2e-53
sp|Q44689|TRPE_BUCRM ANTHRANILATE SYNTHASE COMPONENT I >gi|10820... 210 3e-53
gb|AAG31419.1|AF197464_1 (AF197464) anthranilate synthase compon... 209 4e-53
sp|P42387|TRPE_BUCAP ANTHRANILATE SYNTHASE COMPONENT I >gi|21445... 209 6e-53
gb|AAG31411.1|AF197460_1 (AF197460) anthranilate synthase compon... 208 7e-53
sp|Q44691|TRPE_BUCRP ANTHRANILATE SYNTHASE COMPONENT I >gi|10820... 207 2e-52
gb|AAG31413.1|AF197461_1 (AF197461) anthranilate synthase compon... 207 2e-52
sp|Q44598|TRPE_BUCSC ANTHRANILATE SYNTHASE COMPONENT I >gi|76983... 206 4e-52
pir||H81376 anthranilate synthase (EC 4.1.3.27) chain I Cj0345 [... 205 6e-52
sp|P43761|TRPE_HAEIN ANTHRANILATE SYNTHASE COMPONENT I >gi|10738... 205 9e-52
gb|AAF13810.1|AF130815_2 (AF130815) anthranilate synthase large ... 205 9e-52
gb|AAG18942.1| (AE004995) anthranilate synthase alpha chain; Trp... 205 9e-52
gb|AAG31410.1| (AF197459) anthranilate synthase component I [Buc... 204 1e-51
gi|6320935 anthranilate synthase Component I; Trp2p [Saccharomyc... 203 3e-51
emb|CAA23666.1| (V00368) trpE [Escherichia coli] >gi|43202|emb|C... 203 4e-51
sp|P00895|TRPE_ECOLI ANTHRANILATE SYNTHASE COMPONENT I >gi|74283... 203 4e-51
gb|AAF82323.1|AD001677_1 (AD001677) anthranilate synthase large ... 203 4e-51
gb|AAF01062.1|AF189258_1 (AF189258) aminase [Streptomyces venezu... 200 2e-50
pir||A39812 anthranilate synthase (EC 4.1.3.27) component I (trp... 200 3e-50
sp|Q44697|TRPE_BUCDN ANTHRANILATE SYNTHASE COMPONENT I >gi|13746... 199 4e-50
gb|AAG31408.1| (AF197458) anthranilate synthase component I [Buc... 199 4e-50
sp|P09785|PHNA_PSEAE ANTHRANILATE SYNTHASE COMPONENT I >gi|94751... 198 1e-49
gb|AAF82316.1|L81123_1 (L81123) anthranilate synthase large subu... 198 1e-49
gb|AAG31415.1|AF197462_1 (AF197462) anthranilate synthase compon... 198 1e-49
gi|10957100 anthranilate synthase large subunit [Buchnera sp. AP... 197 2e-49
gb|AAG31417.1|AF197463_1 (AF197463) anthranilate synthase compon... 197 2e-49
sp|P74130|TRE2_SYNY3 ANTHRANILATE SYNTHASE COMPONENT I-LIKE PROT... 197 2e-49
pir||E35116 anthranilate synthase (EC 4.1.3.27) alpha chain - Ps... 196 4e-49
pir||A82777 anthranilate synthase component I XF0674 [imported] ... 196 4e-49
gb|AAD09346.1| (L43555) anthranilate synthase large subunit [Buc... 195 7e-49
sp|P00898|TRPE_SALTY ANTHRANILATE SYNTHASE COMPONENT I >gi|47944... 194 1e-48
pir||NNEB1T anthranilate synthase (EC 4.1.3.27) component I - Sa... 194 1e-48
sp|Q9ZES2|TRPE_BUCTC ANTHRANILATE SYNTHASE COMPONENT I >gi|41601... 194 1e-48
pir||B82622 anthranilate synthase component I XF1914 [imported] ... 193 4e-48
gb|AAF82314.1|L81122_1 (L81122) anthranilate synthase large subu... 192 5e-48
sp|P12679|PABB_KLEAE PARA-AMINOBENZOATE SYNTHASE COMPONENT I (AD... 192 6e-48
gb|AAF82318.1|L81124_1 (L81124) anthranilate synthase large subu... 190 3e-47
sp|P27630|PABB_STRLI PARA-AMINOBENZOATE SYNTHASE COMPONENT I (AD... 188 9e-47
sp|P05041|PABB_ECOLI PARA-AMINOBENZOATE SYNTHASE COMPONENT I (AD... 187 2e-46
sp|P12680|PABB_SALTY PARA-AMINOBENZOATE SYNTHASE COMPONENT I (AD... 185 6e-46
sp|P15395|TRPE_RHIME ANTHRANILATE SYNTHASE [INCLUDES: GLUTAMINE ... 181 1e-44
sp|P32483|PABS_STRGR PARA-AMINOBENZOATE SYNTHASE (P-AMINOBENZOIC... 181 2e-44
pir||B82216 para-aminobenzoate synthase, component I VC1303 [imp... 180 3e-44
sp|O25869|TRPE_HELPY ANTHRANILATE SYNTHASE COMPONENT I >gi|74367... 179 6e-44
sp|P06557|TRPE_BRELA ANTHRANILATE SYNTHASE COMPONENT I >gi|39593... 178 8e-44
pir||B24723 anthranilate synthase (EC 4.1.3.27) component 1 - Co... 178 8e-44
pir||B48967 anthranilate synthase (EC 4.1.3.27) component I - Co... 178 1e-43
sp|Q9ZJU5|TRPE_HELPJ ANTHRANILATE SYNTHASE COMPONENT I >gi|74367... 178 1e-43
gb|AAC79592.1| (AC005727) putative para-aminobenzoate synthase a... 175 1e-42
sp|P27629|PABB_LACLA PARA-AMINOBENZOATE SYNTHASE COMPONENT I (AD... 170 2e-41
pir||F75547 anthranilate synthase component I - Deinococcus radi... 162 7e-39
emb|CAC11935.1| (AL445065) anthranilate synthase component I rel... 156 4e-37
pir||F70398 p-aminobenzoate synthetase - Aquifex aeolicus >gi|29... 152 1e-35
pir||T17434 anthranilate synthase component I ybtS [similarity] ... 141 1e-32
gb|AAD17661.1| (AF069749) unknown [Yersinia pestis] 141 1e-32
pir||S27508 hypothetical protein 2 - Bacillus subtilis >gi|55748... 141 1e-32
sp|P23973|MENF_BACSU MENAQUINONE-SPECIFIC ISOCHORISMATE SYNTHASE... 141 1e-32
sp|P50872|TRPE_AZOBR ANTHRANILATE SYNTHASE [INCLUDES: GLUTAMINE ... 141 2e-32
pir||A71951 p-aminobenzoate synthetase - Helicobacter pylori (st... 140 2e-32
emb|CAB46570.1| (AJ132668) salicylate synthetase, Irp9 [Yersinia... 140 2e-32
pir||E64556 para-aminobenzoate synthetase - Helicobacter pylori ... 138 1e-31
pir||T40823 probable para-aminobenzoate synthase - fission yeast... 134 2e-30
gb|AAC43275.1| (U07755) p-aminobenzoate synthetase [Escherichia ... 131 1e-29
gb|AAC43269.1| (U07748) p-aminobenzoate synthetase [Escherichia ... 131 2e-29
gb|AAC43276.1| (U07756) p-aminobenzoate synthetase [Escherichia ... 131 2e-29
gb|AAC43278.1| (U07758) p-aminobenzoate synthetase [Escherichia ... 131 2e-29
gb|AAC43277.1| (U07757) p-aminobenzoate synthetase [Escherichia ... 130 3e-29
gb|AAG31127.1|AF299336_4 (AF299336) MxcD [Stigmatella aurantiaca] 129 8e-29
pir||F81359 para-aminobenzoate synthase component I (EC 4.1.3.-)... 128 1e-28
gb|AAC43279.1| (U07759) p-aminobenzoate synthetase [Escherichia ... 127 2e-28
sp|P45744|DHBC_BACSU ISOCHORISMATE SYNTHASE DHBC >gi|7428452|pir... 127 3e-28
gb|AAF89583.1|AF166096_1 (AF166096) para-aminobenzoic acid synth... 118 2e-25
sp|O07898|VIBC_VIBCH VIBRIOBACTIN-SPECIFIC ISOCHORISMATE SYNTHAS... 114 2e-24
pir||A81021 para-aminobenzoate synthetase component I/ 4-amino-4... 112 9e-24
pir||D81965 probable para-aminobenzoate synthase component I NMA... 111 2e-23
pir||H70595 probable entC protein - Mycobacterium tuberculosis (... 108 1e-22
sp|P10377|ENTC_ECOLI ISOCHORISMATE SYNTHASE ENTC >gi|68479|pir||... 106 4e-22
gb|AAB40793.1| (U82598) isochorismate synthase [Escherichia coli] 106 4e-22
gb|AAA18491.1| (M36700) iron chelator protein [Escherichia coli] 106 7e-22
gi|6324361 para-aminobenzoate synthase, PABA synthase; Abz1p [Sa... 106 7e-22
sp|P37254|PABS_YEAST PARA-AMINOBENZOATE SYNTHASE (P-AMINOBENZOIC... 104 2e-21
gb|AAB49319.1| (U43608) Abz1p [Saccharomyces cerevisiae] 103 4e-21
pir||A40365 siderophore biosynthetic protein amoA - Aeromonas hy... 102 8e-21
sp|P23300|AMOA_AERHY PUTATIVE ISOCHORISMATE SYNTHASE (AMONABACTI... 102 8e-21
emb|CAA70528.1| (Y09356) isochorismate synthase [Pseudomonas flu... 101 1e-20
sp|P44613|MENF_HAEIN MENAQUINONE-SPECIFIC ISOCHORISMATE SYNTHASE... 100 5e-20
gi|7705929 neutral sphingomyelinase [Homo sapiens] >gi|6606080|g... 98 2e-19
gb|AAF80595.1|AF238500_1 (AF238500) isochorismate synthase [Azot... 96 8e-19
sp|Q51508|PCHA_PSEAE SALICYLATE BIOSYNTHESIS ISOCHORISMATE SYNTH... 96 1e-18
gb|AAD31929.1|AF149719_1 (AF149719) para aminobenzoic acid synth... 89 7e-17
pir||T03800 anthranilate synthase - Streptomyces violaceus >gi|2... 85 1e-15
pir||T35498 probable anthranilate synthase - Streptomyces coelic... 82 1e-14
gb|AAA34840.1| (L15299) para-aminobenzoate synthase [Saccharomyc... 78 1e-13
>pir||A75163 anthranilate synthase component I (trpe) PAB2045 - Pyrococcus
abyssi (strain Orsay) >gi|5457894|emb|CAB49384.1|
(AJ248284) anthranilate synthase component I (trpE)
[Pyrococcus abyssi]
Length = 434
Score = 866 bits (2213), Expect = 0.0
Identities = 434/434 (100%), Positives = 434/434 (100%)
Query: 1 MHVKKLERVEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLD 60
MHVKKLERVEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLD
Sbjct: 1 MHVKKLERVEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLD 60
Query: 61 GKKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWV 120
GKKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWV
Sbjct: 61 GKKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWV 120
Query: 121 FIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKG 180
FIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKG
Sbjct: 121 FIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKG 180
Query: 181 KEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKILVGASPETMG 240
KEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKILVGASPETMG
Sbjct: 181 KEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKILVGASPETMG 240
Query: 241 SVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPG 300
SVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPG
Sbjct: 241 SVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPG 300
Query: 301 SVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDE 360
SVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDE
Sbjct: 301 SVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDE 360
Query: 361 LEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETE 420
LEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETE
Sbjct: 361 LEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETE 420
Query: 421 NKMKAVLKAFGVIQ 434
NKMKAVLKAFGVIQ
Sbjct: 421 NKMKAVLKAFGVIQ 434
>sp|Q9YGB3|TRPE_PYRKO ANTHRANILATE SYNTHASE COMPONENT I >gi|11268486|pir||T43924
anthranilate synthase component I [imported] -
Pyrococcus kodakaraensis >gi|5545306|dbj|BAA82547.1|
(AB030011) component1 of anthranilate synthase
[Thermococcus kodakaraensis]
Length = 433
Score = 633 bits (1615), Expect = e-180
Identities = 303/432 (70%), Positives = 370/432 (85%), Gaps = 1/432 (0%)
Query: 1 MHVKKLERVEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLD 60
M +KKL+ V+P+KLYS +R+F PF+ KDS++A+ TYISA PEF VE+ G+GT +D
Sbjct: 1 MPLKKLKPVDPLKLYSALRDFGMPFMLRSAEKDSRKARFTYISAEPEFVVEV-GEGTEID 59
Query: 61 GKKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWV 120
G++VS+E NP +LK + G F+GGF+GY++YD+VH+ I G IEEPSVFGYYPW
Sbjct: 60 GERVSDERNPLRALKGLMGERVEGRRFMGGFVGYVSYDSVHSIIGGKIEEPSVFGYYPWT 119
Query: 121 FIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKG 180
FIY+H G L F+YLR+ FDPE +VERA+REE + E+GG+E+I TDA EEF+E+V G
Sbjct: 120 FIYDHSTGALSFFYLREAPFDPEALVERARREESRLEDGGSEVISTDAGMEEFVEIVRAG 179
Query: 181 KEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKILVGASPETMG 240
KEYI++GDVFQVVLSREY +R+D+D +E+Y++L+ +NPSPYTFILEF+K +VGASPETMG
Sbjct: 180 KEYIYSGDVFQVVLSREYRVRTDLDALEIYKRLVELNPSPYTFILEFEKTVVGASPETMG 239
Query: 241 SVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPG 300
SVEGRT +INPIAGTAPRG+T EED E+ + LLSDEKERAEHVMLVDLARNDVR+VSKPG
Sbjct: 240 SVEGRTFKINPIAGTAPRGRTGEEDRELEKALLSDEKERAEHVMLVDLARNDVRRVSKPG 299
Query: 301 SVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDE 360
SV+L RFFDV+KYSHVQHIESEV+GEL + K+ FDA+EA+FPAGTLTGAPKIRAMEIIDE
Sbjct: 300 SVRLTRFFDVLKYSHVQHIESEVVGELDEGKNAFDAMEAAFPAGTLTGAPKIRAMEIIDE 359
Query: 361 LEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETE 420
LE+SRR+VYGGA+GYFS+TG AD AIAIRMAEIEGRKA VRAGAGIVADS+PEKEF+ETE
Sbjct: 360 LERSRRKVYGGAVGYFSLTGDADMAIAIRMAEIEGRKASVRAGAGIVADSVPEKEFFETE 419
Query: 421 NKMKAVLKAFGV 432
NKM+AVLKA GV
Sbjct: 420 NKMRAVLKALGV 431
>gi|11499196 anthranilate synthase component I (trpE) {Methanococcus jannaschii)
[Archaeoglobus fulgidus]
>gi|3334386|sp|O28669|TRPE_ARCFU ANTHRANILATE SYNTHASE
COMPONENT I >gi|7436740|pir||B69450 anthranilate
synthase component I (trpE) homolog - Archaeoglobus
fulgidus >gi|2648957|gb|AAB89646.1| (AE000992)
anthranilate synthase component I (trpE) {Methanococcus
jannaschii) [Archaeoglobus fulgidus]
Length = 411
Score = 406 bits (1032), Expect = e-112
Identities = 224/430 (52%), Positives = 301/430 (69%), Gaps = 19/430 (4%)
Query: 3 VKKLERVEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGK 62
++K E V P+KLYS IR+ + PFI K + A+ TYIS +P +TV + G T +DG+
Sbjct: 1 MQKHEYVNPVKLYSAIRDEKFPFILESAEKSGR-ARYTYISFNPLYTVRV-GSRTRVDGE 58
Query: 63 KVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWVFI 122
+S ++PF +L ++ G +GY+AY+AV NYI + PSVFG Y F+
Sbjct: 59 VISKISDPFDALNEIHVK--------GLLVGYVAYEAVKNYIGKKPQTPSVFGCYDGYFV 110
Query: 123 YNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKE 182
Y+H +L + + + IVERAKR E++ G +E++R +RE+F +MVE+GKE
Sbjct: 111 YDHYLRKLFSVNVENA----DKIVERAKRVEVEQVRGNSEVLRA-GSREKFEKMVERGKE 165
Query: 183 YIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKILVGASPETMGSV 242
IF G+V+Q+VLSREYV+ +D+ P ++Y L NPSPY F+LEF + L+G+SPETMG V
Sbjct: 166 QIFEGEVYQIVLSREYVVDTDLSPFQMYLNLRETNPSPYMFLLEFDRALIGSSPETMGRV 225
Query: 243 EGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSV 302
EG + INPIAGTA R E+ EI +LLSDEKERAEHVMLVDLARNDVRKV + GSV
Sbjct: 226 EGNSFIINPIAGTARREAGREK--EIAEKLLSDEKERAEHVMLVDLARNDVRKVCRAGSV 283
Query: 303 KLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELE 362
++ RF +V++Y V HIESEV+GEL FDA++A+FPAGT+TGAPK+RA+E+IDE+E
Sbjct: 284 RVSRFMEVVEYPSVLHIESEVVGELKAGVTHFDAMKATFPAGTVTGAPKLRAIELIDEIE 343
Query: 363 KSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENK 422
R VY GA+GYFS +D AIAIRM E +G KA +RAGAGIVADS+PE+EF+ETENK
Sbjct: 344 GDCRGVYAGAVGYFS-ENVSDLAIAIRMIEFDG-KARIRAGAGIVADSVPEREFFETENK 401
Query: 423 MKAVLKAFGV 432
+ VL+A G+
Sbjct: 402 IARVLRAVGL 411
>sp|Q58475|TRPE_METJA ANTHRANILATE SYNTHASE COMPONENT I >gi|2127760|pir||B64434
anthranilate synthase (EC 4.1.3.27) subunit I -
Methanococcus jannaschii >gi|1591723|gb|AAB99074.1|
(U67550) anthranilate synthase component I (trpE)
[Methanococcus jannaschii]
Length = 474
Score = 299 bits (757), Expect = 5e-80
Identities = 196/481 (40%), Positives = 275/481 (56%), Gaps = 67/481 (13%)
Query: 1 MHVKKLER-VEPIKLYSVIREFENPFI------------FTIIGKDSKEAKLTYISASPE 47
M +KK++ V P+ +Y IR EN F+ ++I+GK + E
Sbjct: 1 MIIKKIKMDVCPLDVYEQIRG-ENTFLLESAEGVPKVARYSILGKAEGKVIFKNGKLKVE 59
Query: 48 FTVEISGKGTFLDGK---------KVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYD 98
E K L+GK +V NE ++ + + F GG +GY++YD
Sbjct: 60 SFTEFGDKAKDLEGKYECPLDALREVRNEYLKYIDISNIEPIPR----FKGGLVGYLSYD 115
Query: 99 AVHNYIEGSIEEPSVFGYYPWVFIYNHGKGELRFYYLRD-PSFD---------------- 141
+ +I+ S P + + F+ ++D SFD
Sbjct: 116 IIRYWIDLSNINPKPINDLKF--------PDAEFFIVKDFISFDLKEKVINLIAEDDEGI 167
Query: 142 --PETIVERAK------REELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVV 193
E I++ AK +EE EN + I+++ ++EEF+E V+K KEYIFAGD+FQVV
Sbjct: 168 RELERIIKNAKIGNNDNKEEKTTENKDLK-IKSNMSKEEFIEAVKKAKEYIFAGDIFQVV 226
Query: 194 LSREYVLRSD-VDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVE----GRTV 247
LSR + D +D +++Y+K+ INPSPY + L+F + ++G+SPE + + R V
Sbjct: 227 LSRRIEIDLDNLDHLKIYKKVREINPSPYMYYLDFGDRKIIGSSPEILVRTDYKDNKRLV 286
Query: 248 RINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRF 307
PIAGT RGKT EED+E+ ++LLSDEKERAEHVMLVDLARND+ K+SK G+V++ F
Sbjct: 287 ITRPIAGTIRRGKTEEEDKELEKKLLSDEKERAEHVMLVDLARNDIGKISKFGTVEVTDF 346
Query: 308 FDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRR 367
+ KYSHVQHI S V+GEL D+ D F A++A+FPAGTL+GAPK+RAMEII+ELEK+ R
Sbjct: 347 MIIEKYSHVQHIVSNVVGELKDNYDSFLAVKATFPAGTLSGAPKVRAMEIIEELEKTWRG 406
Query: 368 VYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
YGG +GYF D AI IR I K +++ GAGIVADSIPE E+ ETE K A +
Sbjct: 407 PYGGGVGYFGWDDLMDLAITIRTFVISKNKGYIQVGAGIVADSIPENEWEETERKGMANV 466
Query: 428 K 428
K
Sbjct: 467 K 467
>sp|O27692|TRPE_METTH ANTHRANILATE SYNTHASE COMPONENT I >gi|7436734|pir||C69088
anthranilate synthase component I - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622783|gb|AAB86127.1| (AE000924) anthranilate
synthase component I [Methanobacterium
thermoautotrophicum]
Length = 464
Score = 298 bits (756), Expect = 6e-80
Identities = 174/439 (39%), Positives = 255/439 (57%), Gaps = 20/439 (4%)
Query: 4 KKLERVEPIKLY-SVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLD-- 60
+K+E EP +L+ S+ E+++ F+ + D+ A+ +++ P+ + + F++
Sbjct: 15 EKIEFKEPFELFKSIYSEYDSSFLLESMESDTGLARYSFMGFEPQMIIR--ARSGFIEVE 72
Query: 61 --GKKVSNET-NPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSV---- 113
G + +T NPF L+ F + GF GG +GYI+Y A + ++ +
Sbjct: 73 YEGSREEFDTENPFEFLRQFTRPAGKSRGFCGGLVGYISYQAARFFDSINLSPGNFPDFE 132
Query: 114 FGYYPWVFIYNHGKGELRFYYLRDPSFDP--ETIVERAKREELKFENGGAEIIRTDANRE 171
FG + ++NH GE + L++ E + E LK+ + G T +R
Sbjct: 133 FGLFLDGIMFNHLTGECSYISLKENRLPEISELLREETPTGHLKYRSMG-----TLFSRR 187
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF-KKI 230
++ MVE+ +E I G++FQ VLS R D + LY L +NPSPY + L+ +
Sbjct: 188 RYLGMVEEARERIAEGEIFQAVLSNATDYRLRGDRLALYEALRRVNPSPYMYHLKLGSRE 247
Query: 231 LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLAR 290
+ G+SPE + VE + + PIAGT PRGKTP EDE I LLSDEKE AEH+MLVDLAR
Sbjct: 248 ITGSSPEMLVRVEDKQIETFPIAGTRPRGKTPHEDERIAAELLSDEKELAEHLMLVDLAR 307
Query: 291 NDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAP 350
ND+ ++S+ G+V++ + + ++SHVQHI S V G L D DA+ A FPAGT++GAP
Sbjct: 308 NDLGRISEFGTVQVPEYMTIRRFSHVQHILSHVTGRLRKGMDALDALGAVFPAGTVSGAP 367
Query: 351 KIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADS 410
KIRAMEII+ LE R Y GA+GY S+ G ADFAI IR EG ++AGAGIV DS
Sbjct: 368 KIRAMEIIESLEGVPRNAYAGALGYLSLNGNADFAITIRSMVAEGAYGRIQAGAGIVHDS 427
Query: 411 IPEKEFYETENKMKAVLKA 429
+PE+E+ E +NK AVLK+
Sbjct: 428 VPEREYVECQNKAMAVLKS 446
>sp|P33975|TRPE_HALVO ANTHRANILATE SYNTHASE COMPONENT I >gi|99224|pir||A42301
anthranilate synthase (EC 4.1.3.27) alpha chain -
Haloferax volcanii >gi|149039|gb|AAA73177.1| (M83788)
anthranilate synthase [Haloferax volcanii]
Length = 523
Score = 297 bits (752), Expect = 2e-79
Identities = 181/367 (49%), Positives = 226/367 (61%), Gaps = 26/367 (7%)
Query: 89 GGFMGYIAYDAVHNYIEGSI--EEPSV------FGYYPWVFIYNHGKGELRFYY--LRDP 138
GG +G++AY+AV++ + E P F ++H + +R + P
Sbjct: 144 GGLVGFLAYEAVYDLWLDEVGRERPDTDDPDAEFVLTTRTLSFDHREDAVRLVCTPVVSP 203
Query: 139 SFDP----ETIVERAKR--EELKFEN----GGAEIIRTDA-NREEFMEMVEKGKEYIFAG 187
DP + +V A+R E+L+ + GG E DA +REE+ V K KE++ G
Sbjct: 204 DDDPGEVYDGVVAEAERVAEKLRAADDPAPGGFERTGEDAGSREEYEAAVRKTKEHVRDG 263
Query: 188 DVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEGRT 246
D++Q V+SR LR VDPV LY L +NPSPY F+L + +VGASPET+ SV G
Sbjct: 264 DIYQGVISRTRKLRGQVDPVGLYASLREVNPSPYMFLLRHGDRRVVGASPETLVSVRGDR 323
Query: 247 VRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVR 306
V +NPIAGT RG P ED + LL+D KERAEH MLVDL RNDVR+VS PGSV++
Sbjct: 324 VVVNPIAGTCQRGSGPVEDRRLAGELLADAKERAEHTMLVDLGRNDVRRVSTPGSVRVED 383
Query: 307 FFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRR 366
F +IKYSHVQHIES V G L D D FDA A+FPAGTLTGAPK+RAMEIID+LE R
Sbjct: 384 FMSIIKYSHVQHIESTVSGTLDADADAFDATRATFPAGTLTGAPKVRAMEIIDDLEAEPR 443
Query: 367 RVYGGAIGYFSITGYADFAIAIRMAEIEGRKAH----VRAGAGIVADSIPEKEFYETENK 422
VYGG +GY+S TG AD AI IR A ++ A VRAGAGIVADS P E+ ETE K
Sbjct: 444 GVYGGGVGYYSWTGDADVAIVIRTATVDSGGADDAITVRAGAGIVADSDPTAEYEETEQK 503
Query: 423 MKAVLKA 429
M VL A
Sbjct: 504 MGGVLDA 510
>sp|Q08653|TRPE_THEMA ANTHRANILATE SYNTHASE COMPONENT I >gi|7436736|pir||D72414
anthranilate synthase (EC 4.1.3.27) component I -
Thermotoga maritima (strain MSB8)
>gi|4980634|gb|AAD35235.1|AE001699_12 (AE001699)
anthranilate synthase component I [Thermotoga maritima]
Length = 461
Score = 295 bits (748), Expect = 5e-79
Identities = 165/361 (45%), Positives = 234/361 (64%), Gaps = 19/361 (5%)
Query: 87 FLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWV-----FIYNHGKGELRFYYLRDPSFD 141
F GG +G+++YD + +YIE + SVF + +V I++H K + + + D
Sbjct: 100 FRGGAVGFVSYDYI-SYIEKVKVKASVFPTFYFVVPEHLIIFDHLKNNV--FIISD---S 153
Query: 142 PETIVERAKR--EELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYV 199
PE + + EE +N ++ RE+F ++VEK K+YI GD+FQVVLS+ +
Sbjct: 154 PEELTSKVLSPFEEKPEKNVFVTEPESNFEREQFYKVVEKAKKYIVEGDIFQVVLSQAFT 213
Query: 200 LRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEGRTVRINPIAGTAPR 258
++ +DP +YR L INPSPY F L+F +++G+SPETM VEG + PIAGT PR
Sbjct: 214 FKTTLDPFYIYRALRMINPSPYMFYLKFGDTVVLGSSPETMAKVEGDKATVKPIAGTRPR 273
Query: 259 GKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQH 318
G+T EED ++ R LL+DEKE AEHVMLVDL RND+ +V K G+V++ + + +YSHV H
Sbjct: 274 GRTVEEDLKLERELLNDEKEIAEHVMLVDLGRNDLGRVCKEGTVRVEKKMVIERYSHVMH 333
Query: 319 IESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSI 378
I S+V GEL DDKD D EA+FPAGT++GAPK+RAMEII+ELE + R Y GA+GYFS
Sbjct: 334 IVSQVSGELKDDKDAVDVFEATFPAGTVSGAPKVRAMEIIEELEPTPRGPYAGAVGYFSF 393
Query: 379 TG-----YADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVI 433
D AI IR +G++ ++AGAGIV DS+PE+E+ ET NK++A+ ++ V
Sbjct: 394 PDDKGRMNMDSAITIRSFFFKGKQGWLQAGAGIVYDSVPEREYQETLNKLRALFRSLEVA 453
Query: 434 Q 434
Q
Sbjct: 454 Q 454
>pir||S34746 anthranilate synthase (EC 4.1.3.27) component I - Thermotoga
maritima >gi|600087|emb|CAA52202.1| (X74075)
anthranilate synthase component I [Thermotoga maritima]
Length = 457
Score = 295 bits (747), Expect = 7e-79
Identities = 165/361 (45%), Positives = 234/361 (64%), Gaps = 19/361 (5%)
Query: 87 FLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWV-----FIYNHGKGELRFYYLRDPSFD 141
F GG +G+++YD + +YIE + SVF + +V I++H K + + + D
Sbjct: 96 FRGGRVGFVSYDYI-SYIEKVKVKASVFPTFYFVVPEHLIIFDHLKNNV--FIISD---S 149
Query: 142 PETIVERAKR--EELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYV 199
PE + + EE +N ++ RE+F ++VEK K+YI GD+FQVVLS+ +
Sbjct: 150 PEELTSKVLSPFEEKPEKNVFVTEPESNFEREQFYKVVEKAKKYIVEGDIFQVVLSQAFT 209
Query: 200 LRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEGRTVRINPIAGTAPR 258
++ +DP +YR L INPSPY F L+F +++G+SPETM VEG + PIAGT PR
Sbjct: 210 FKTTLDPFYIYRALRMINPSPYMFYLKFGDTVVLGSSPETMAKVEGDKATVKPIAGTRPR 269
Query: 259 GKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQH 318
G+T EED ++ R LL+DEKE AEHVMLVDL RND+ +V K G+V++ + + +YSHV H
Sbjct: 270 GRTVEEDLKLERELLNDEKEIAEHVMLVDLGRNDLGRVCKEGTVRVEKKMVIERYSHVMH 329
Query: 319 IESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSI 378
I S+V GEL DDKD D EA+FPAGT++GAPK+RAMEII+ELE + R Y GA+GYFS
Sbjct: 330 IVSQVSGELKDDKDAVDVFEATFPAGTVSGAPKVRAMEIIEELEPTPRGPYAGAVGYFSF 389
Query: 379 TG-----YADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVI 433
D AI IR +G++ ++AGAGIV DS+PE+E+ ET NK++A+ ++ V
Sbjct: 390 PDDKGRMNMDSAITIRSFFFKGKQGWLQAGAGIVYDSVPEREYQETLNKLRALFRSLEVA 449
Query: 434 Q 434
Q
Sbjct: 450 Q 450
>sp|P26940|TRPE_METTM ANTHRANILATE SYNTHASE COMPONENT I >gi|99101|pir||A40362
anthranilate synthase (EC 4.1.3.27) alpha chain, trpE -
Methanobacterium thermoautotrophicum (strain Marburg)
>gi|149745|gb|AAA73028.1| (M65060) anthranilate synthase
alpha-subunit [Methanobacterium thermoautotrophicum]
Length = 462
Score = 291 bits (737), Expect = 1e-77
Identities = 178/437 (40%), Positives = 255/437 (57%), Gaps = 15/437 (3%)
Query: 4 KKLERVEPIKLY-SVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFL--- 59
+KLE EP +++ S+ E+E+ F+ + D+ A+ ++I PE + + +G
Sbjct: 17 EKLEFREPFEVFKSIYSEYESSFLLESMESDTGLARYSFIGFEPEMIIR-AREGVIEIDD 75
Query: 60 -DGKKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSV----F 114
D ++ + NPF L+ F + GF GG +GYI+Y A + + E F
Sbjct: 76 GDSREEFDSKNPFEDLRGFLKMEKNSGGFCGGLVGYISYQAARFFDTIRLSEGDFPDFEF 135
Query: 115 GYYPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFM 174
G + ++NH GE Y R + P+ + +E+ G RT ++ +M
Sbjct: 136 GLFLDGIMFNHLTGECS-YISRHGNRLPD--ISPLLGDEVPTGTLGYRRERTLLSKRRYM 192
Query: 175 EMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF-KKILVG 233
+MV + KE I G++FQ VLS R D + Y L INPSPY + L+ ++ + G
Sbjct: 193 DMVLEAKERIREGEIFQAVLSSATDYRLRGDRLAFYESLRRINPSPYMYHLKLGEREITG 252
Query: 234 ASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKER-AEHVMLVDLARND 292
+SPE + VE R + PIAGT PRG+T EED I LLSDEKE+ AEH+MLVDLARND
Sbjct: 253 SSPEMLVRVEDRRIETFPIAGTRPRGRTEEEDGVIASDLLSDEKEQLAEHLMLVDLARND 312
Query: 293 VRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKI 352
+ +VS+ GSV++ + + ++SHVQHI S V G+L D D DA+ A FPAGT++GAPKI
Sbjct: 313 IGRVSEFGSVEVPEYMTIKRFSHVQHILSHVTGKLRDGMDAVDALGAVFPAGTVSGAPKI 372
Query: 353 RAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIP 412
RAMEII+ LE R Y GA+GY S+ G ADFAI IR +G+ ++AGAGIV DSIP
Sbjct: 373 RAMEIIESLEGVPRNAYAGALGYLSLNGNADFAITIRSMVCQGKTGRIQAGAGIVHDSIP 432
Query: 413 EKEFYETENKMKAVLKA 429
E E+ E +NK +A+LK+
Sbjct: 433 EMEYLECQNKARALLKS 449
>sp|O66849|TRPE_AQUAE ANTHRANILATE SYNTHASE COMPONENT I >gi|7436733|pir||E70352
anthranilate synthase component I - Aquifex aeolicus
>gi|2983197|gb|AAC06796.1| (AE000696) anthranilate
synthase component I [Aquifex aeolicus]
Length = 494
Score = 289 bits (733), Expect = 3e-77
Identities = 164/372 (44%), Positives = 229/372 (61%), Gaps = 24/372 (6%)
Query: 87 FLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW-------VFIYNHGKGELRFYYLRDPS 139
F GG +GY AYD V Y + P Y V I+++ G+++
Sbjct: 118 FWGGLVGYFAYDVVKFYEPVEDKNPDPIHTYDIYLVLTDVVVIHDNLTGKIKVVVPIFAQ 177
Query: 140 FDPETIVERAK---REELK-FENGGAEII------------RTDANREEFMEMVEKGKEY 183
E ERAK R+ +K + G + R++ +EEF ++V+K KEY
Sbjct: 178 NGIEEEYERAKNLIRDTVKKLKERGTTFLNVVEKEPDFKNWRSNFTKEEFEDIVKKAKEY 237
Query: 184 IFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPETMGSV 242
I GDV QVVLS+ + R +P +YR L +NPSPY + L+F ++ ++G+SPE + +
Sbjct: 238 IAQGDVIQVVLSQRFRKRFKGNPDNIYRVLRFLNPSPYMYYLDFDQLKVIGSSPEILVRL 297
Query: 243 EGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSV 302
E + PIAGT RG+T EED+ + LLSDEKERAEH+MLVDLARND+ +V+K GSV
Sbjct: 298 EEGRIETRPIAGTRKRGRTEEEDKRLEEDLLSDEKERAEHLMLVDLARNDIGRVAKTGSV 357
Query: 303 KLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELE 362
++ F + +YSHV HI S+V+GEL + D D ++A+FPAGT++GAPK+RAM+II+ELE
Sbjct: 358 RVENFMRIERYSHVMHIVSDVVGELREGYDALDVLKATFPAGTVSGAPKVRAMQIIEELE 417
Query: 363 KSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENK 422
RR +Y G++GY S G D AIAIR A R V+AGAGIVADS+PEKE+ ET NK
Sbjct: 418 NERRGIYAGSVGYISFQGNMDMAIAIRTAVYRDRDIFVQAGAGIVADSVPEKEWEETVNK 477
Query: 423 MKAVLKAFGVIQ 434
KA++KA + +
Sbjct: 478 AKALMKAIEIAE 489
>sp|P14953|TRPE_CLOTM ANTHRANILATE SYNTHASE COMPONENT I >gi|80536|pir||JX0065
anthranilate synthase (EC 4.1.3.27) component I -
Clostridium thermocellum >gi|216421|dbj|BAA00300.1|
(D00399) trpE [Clostridium thermocellum]
>gi|363844|prf||1505348A anthranilate synthase I
[Clostridium thermocellum]
Length = 494
Score = 280 bits (709), Expect = 2e-74
Identities = 179/456 (39%), Positives = 252/456 (55%), Gaps = 38/456 (8%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFL---DGKKVSNE 67
PI L+ E F+ + K A+ + I +P VE T + +G + E
Sbjct: 32 PISLFKRFEESSCCFLLESVEGGEKWARYSIIGKNPFLVVESYKNKTIIRERNGSQREVE 91
Query: 68 TNPFLSLKSFNMDSASGSG------FLGGFMGYIAYDAVHNYIE-GSIEEPSV------F 114
NP +K M G+ F GG +GY YD + +Y ++ E + F
Sbjct: 92 GNPVEIIKGI-MGKFKGANLPNLPRFNGGAVGYFGYDLIRHYENLPNVPEDDMGLPECHF 150
Query: 115 GYYPWVFIYNHGK------------GELRFYYL----RDPSFDPETIVERAKREE---LK 155
+ V +Y+H K G + Y+ R + E + R K + L
Sbjct: 151 MFTDEVLVYDHLKQKIHIIVNLHVNGNIERAYISAVDRIKTIHREILDTRWKTADNSVLS 210
Query: 156 FENGGAEI-IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLI 214
+ E+ + ++ ++E+F V K K+YI GD+FQVVLS+ + ++ +P +YR L
Sbjct: 211 YNKKKNELAVTSNISKEDFCRNVLKAKQYIRDGDIFQVVLSQRLCVETNENPFNIYRALR 270
Query: 215 SINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLL 273
INPSPY + L+F ++G+SPE + VE V PIAGT RG+T EEDE + + LL
Sbjct: 271 VINPSPYMYYLKFGGYRIIGSSPEMLVRVENGIVETCPIAGTRKRGRTKEEDEALEKELL 330
Query: 274 SDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDM 333
SDEKE AEHVMLVDL RND+ +VSK G+V + + +YSHV H+ + V GE+ +DK
Sbjct: 331 SDEKEIAEHVMLVDLGRNDIGRVSKFGTVAVKNLMHIERYSHVMHVVTNVQGEIREDKTP 390
Query: 334 FDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEI 393
FDA+ + PAGTL+GAPK+RAMEIIDELE +R YGGAIGY S G D I IR +
Sbjct: 391 FDALMSILPAGTLSGAPKVRAMEIIDELETVKRGPYGGAIGYLSFNGNLDSCITIRTIIL 450
Query: 394 EGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+ KA+V+AGAGIVADS+PE+E+ E NK A+LKA
Sbjct: 451 KDGKAYVQAGAGIVADSVPEREYEECYNKAMALLKA 486
>dbj|BAB05378.1| (AP001512) anthranilate synthase [Bacillus halodurans]
Length = 502
Score = 276 bits (699), Expect = 3e-73
Identities = 177/461 (38%), Positives = 259/461 (55%), Gaps = 58/461 (12%)
Query: 17 VIREFENPFIFTIIGKDSKE--AKLTYISASPEFTV--------EISGKGTFL----DGK 62
++++ + F + KD + A+ ++I +P + IS G+ L D K
Sbjct: 35 IVQQLGDEVAFILESKDDESPWARFSFIGLNPFVELIEQNGVYQSISRSGSILVETEDFK 94
Query: 63 KVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSI------EEPSV-FG 115
+T L ++ + F GG +GY+AYDA+ IE ++ E P F
Sbjct: 95 SCLQQTIDVLDVQPLERELP----FYGGAVGYMAYDAIET-IEKTLANARESEAPLYHFL 149
Query: 116 YYPWVFIYNHGKGELRFYYLRDP---SFDP---------ETIVERAKR------------ 151
+ + +Y+H + +L YL S D ET+VE +
Sbjct: 150 FCETLIVYDHTEKKLAVIYLSTEDGGSLDTRYKCAVNTIETVVETIHKRRDGDRLLRPAP 209
Query: 152 --EELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVEL 209
+E+ F+ + ++ +E F+ VE+ KEYI AGDVFQ VLS+ + V +++
Sbjct: 210 VQDEVSFQE-----VSSNYEKEVFLRDVERIKEYIRAGDVFQAVLSQRFERELSVRALDV 264
Query: 210 YRKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEI 268
YR L INPSPY F ++F + +VG+SPE + V+ V I+PIAGT RG T EEDE +
Sbjct: 265 YRVLRMINPSPYLFYIKFHDVEVVGSSPERLVQVQDGHVEIHPIAGTRKRGATREEDEAL 324
Query: 269 RRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELA 328
+ LL+DEKERAEH MLVDLARND+ ++++ G+VK ++ K+SHV HI S+V GEL
Sbjct: 325 AKELLADEKERAEHYMLVDLARNDIGRIAEYGTVKTPTLLEIGKFSHVMHIISKVTGELK 384
Query: 329 DDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAI 388
DA+ FPAGT++GAPKIRAMEI++ELE ++R +Y GAI Y G D IAI
Sbjct: 385 QTLHPLDALRYGFPAGTVSGAPKIRAMEILNELEPTKRGIYAGAIAYLGFDGNIDSCIAI 444
Query: 389 RMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
R ++ +A+++AGAGIVADS+PE E+ ET NK KA+LKA
Sbjct: 445 RTMIVKDGRAYIQAGAGIVADSVPENEYEETRNKAKALLKA 485
>gb|AAG19902.1| (AE005074) anthranilate synthase alpha chain; TrpE1 [Halobacterium
sp. NRC-1]
Length = 527
Score = 271 bits (686), Expect = 1e-71
Identities = 164/366 (44%), Positives = 210/366 (56%), Gaps = 25/366 (6%)
Query: 89 GGFMGYIAYDAVHNYI--EGSIEEPSV------FGYYPWVFIYNHGKGELRFYYLRDPSF 140
GG +G++AYDAV++ E +E P F +++ +
Sbjct: 147 GGLVGFLAYDAVYDLWLDEVGVERPPTPLPDAEFAVTTRTLVFDRATDSVSLVCTPVADA 206
Query: 141 DPETIVERAKREELKF-----------ENGGAEIIRTDA-NREEFMEMVEKGKEYIFAGD 188
D T V A E K G E+ A +R+ + + VE + G+
Sbjct: 207 DTATDVYDALEAEAKRVQAVLRDATAPATAGIEVTTERAGDRDAYTDAVETAATAVRDGE 266
Query: 189 VFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEGRTV 247
V+Q V+SR L D+DP LY L ++NPSPY F+L +VGASPET+ +V TV
Sbjct: 267 VYQAVVSRTRELDGDIDPRALYDALRAVNPSPYMFLLAHGDHTVVGASPETLVAVHDDTV 326
Query: 248 RINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRF 307
NPIAGT RG +P D + +L+DEKERAEH MLVDLARNDVR+VS PG+V + F
Sbjct: 327 VTNPIAGTCQRGASPVADRRLAGEMLADEKERAEHTMLVDLARNDVRRVSAPGTVSVPEF 386
Query: 308 FDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRR 367
V+KYSHVQHIES V G LA D D FDA A+FPAGTL+GAPK+RAME ID +E + R
Sbjct: 387 MRVLKYSHVQHIESTVTGTLAADADAFDATRAAFPAGTLSGAPKVRAMEHIDAIEATPRG 446
Query: 368 VYGGAIGYFSITGYADFAIAIRMAEI----EGRKAHVRAGAGIVADSIPEKEFYETENKM 423
+YGG +GYFS TG A+ AI IR I + VRAGAG+VADS P+ E+ ETE KM
Sbjct: 447 IYGGGVGYFSWTGDAELAITIRSGTITHTGDEDTLTVRAGAGVVADSDPDAEYEETEAKM 506
Query: 424 KAVLKA 429
VL A
Sbjct: 507 DGVLAA 512
>sp|P23315|TRPE_ACICA ANTHRANILATE SYNTHASE COMPONENT I >gi|95307|pir||S11891
anthranilate synthase (EC 4.1.3.27) - Acinetobacter
calcoaceticus >gi|38754|emb|CAA35960.1| (X51633)
anthranilate synthase [Acinetobacter calcoaceticus]
Length = 497
Score = 270 bits (684), Expect = 2e-71
Identities = 162/373 (43%), Positives = 219/373 (58%), Gaps = 34/373 (9%)
Query: 87 FLGGFMGYIAYDAVHNYIE---GSIEEPSVFGYYP-WVFIYNHGKGELRFYYLRDPSF-- 140
F GG +GY YDAV YIE ++ E G W+ + K + F L+D F
Sbjct: 119 FTGGLVGYFGYDAVR-YIEPRLSNVPEADPVGLPDIWMML---SKTVIIFDNLKDTLFLI 174
Query: 141 -----DPETIVERAKRE------------ELKFENGGAEIIRTDANREEFMEMVEKGKEY 183
E +RA+ + L+ + A + +E+F+E VE KEY
Sbjct: 175 VHANTTDEEAYQRAQNQLDYLERLLATPVSLQAKKHKAPHFESLTGKEKFLESVETVKEY 234
Query: 184 IFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-------LVGASP 236
I AGDV QVV V D DP+++YR L +NPSPY F+++ + +VG+SP
Sbjct: 235 IRAGDVMQVVPGHRMVSDFDGDPLQVYRALRHLNPSPYLFLVQGHTLTDNTPFHIVGSSP 294
Query: 237 ETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKV 296
E + +E + P+AGT PRGKT EED + + LL+DEKE AEH+ML+DL RNDV +V
Sbjct: 295 EILSRLEDGIATVRPLAGTRPRGKTKEEDLALEQELLADEKEIAEHLMLIDLGRNDVGRV 354
Query: 297 SKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAME 356
SK G V++ + +YSHV HI S V GE+ DD D D +A+FPAGTL+GAPKIRAME
Sbjct: 355 SKIGKVQVTDRMVIERYSHVMHIVSNVQGEVRDDIDALDVFKATFPAGTLSGAPKIRAME 414
Query: 357 IIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEF 416
IIDE+E +R ++GGA+GY G D +IAIR I K +V+AGAG+VADS PE E+
Sbjct: 415 IIDEVEPVKRGIFGGAVGYLGWHGEMDMSIAIRTCVIRENKVYVQAGAGLVADSNPESEW 474
Query: 417 YETENKMKAVLKA 429
ET+ K +AV+KA
Sbjct: 475 NETQIKARAVIKA 487
>pdb|1QDL|A Chain A, The Crystal Structure Of Anthranilate Synthase From
Sulfolobus Solfataricus
Length = 422
Score = 265 bits (671), Expect = 6e-70
Identities = 170/428 (39%), Positives = 241/428 (55%), Gaps = 26/428 (6%)
Query: 18 IREFENPF-IFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGK-KVSNETNPFLS-- 73
I EF +PF +F I +D K A L P++ S +G K+ ++ L+
Sbjct: 7 ISEFASPFEVFKCIERDFKVAGLLESIGGPQYKARYSVIAWSTNGYLKIHDDPVNILNGY 66
Query: 74 LKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW--------VFIYNH 125
LK + G F GG +GYI+YDAV + + +P+ +P+ + IY+H
Sbjct: 67 LKDLKLADIPGL-FKGGMIGYISYDAVRFWEKIRDLKPAAED-WPYAEFFTPDNIIIYDH 124
Query: 126 GKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIF 185
+G++ + D ++ E K N+ + +V + EYI
Sbjct: 125 NEGKVYV------NADLSSVGGCGDIGEFK-----VSFYDESLNKNSYERIVSESLEYIR 173
Query: 186 AGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEG 244
+G +FQVVLSR Y DP+ +Y L INPSPY F L+F +K L+G+SPE + V+
Sbjct: 174 SGYIFQVVLSRFYRYIFSGDPLRIYYNLRRINPSPYMFYLKFDEKYLIGSSPELLFRVQD 233
Query: 245 RTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKL 304
V PIAGT PRG EED ++ L++ EK++AEH+MLVDLARND+ KV PG+VK+
Sbjct: 234 NIVETYPIAGTRPRGADQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVKV 293
Query: 305 VRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKS 364
V KYSHVQHI S+VIG L + + + A+FPAGT++GAPK AM II+ LE+
Sbjct: 294 PELMYVEKYSHVQHIVSKVIGTLKKKYNALNVLSATFPAGTVSGAPKPMAMNIIETLEEY 353
Query: 365 RRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMK 424
+R Y GA+G+ S G A+FAIAIR A + + AGAGIV DS PE E++ETE+K+K
Sbjct: 354 KRGPYAGAVGFISADGNAEFAIAIRTAFLNKELLRIHAGAGIVYDSNPESEYFETEHKLK 413
Query: 425 AVLKAFGV 432
A+ A GV
Sbjct: 414 ALKTAIGV 421
>gb|AAK41175.1| Anthranilate synthase component I (trpE) [Sulfolobus solfataricus]
Length = 421
Score = 265 bits (671), Expect = 6e-70
Identities = 170/428 (39%), Positives = 241/428 (55%), Gaps = 26/428 (6%)
Query: 18 IREFENPF-IFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGK-KVSNETNPFLS-- 73
I EF +PF +F I +D K A L P++ S +G K+ ++ L+
Sbjct: 6 ISEFASPFEVFKCIERDFKVAGLLESIGGPQYKARYSVIAWSTNGYLKIHDDPVNILNGY 65
Query: 74 LKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW--------VFIYNH 125
LK + G F GG +GYI+YDAV + + +P+ +P+ + IY+H
Sbjct: 66 LKDLKLADIPGL-FKGGMIGYISYDAVRFWEKIRDLKPAAED-WPYAEFFTPDNIIIYDH 123
Query: 126 GKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIF 185
+G++ + D ++ E K N+ + +V + EYI
Sbjct: 124 NEGKVYV------NADLSSVGGCGDIGEFK-----VSFYDESLNKNSYERIVSESLEYIR 172
Query: 186 AGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEG 244
+G +FQVVLSR Y DP+ +Y L INPSPY F L+F +K L+G+SPE + V+
Sbjct: 173 SGYIFQVVLSRFYRYIFSGDPLRIYYNLRRINPSPYMFYLKFDEKYLIGSSPELLFRVQD 232
Query: 245 RTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKL 304
V PIAGT PRG EED ++ L++ EK++AEH+MLVDLARND+ KV PG+VK+
Sbjct: 233 NIVETYPIAGTRPRGADQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVKV 292
Query: 305 VRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKS 364
V KYSHVQHI S+VIG L + + + A+FPAGT++GAPK AM II+ LE+
Sbjct: 293 PELMYVEKYSHVQHIVSKVIGTLKKKYNALNVLSATFPAGTVSGAPKPMAMNIIETLEEY 352
Query: 365 RRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMK 424
+R Y GA+G+ S G A+FAIAIR A + + AGAGIV DS PE E++ETE+K+K
Sbjct: 353 KRGPYAGAVGFISADGNAEFAIAIRTAFLNKELLRIHAGAGIVYDSNPESEYFETEHKLK 412
Query: 425 AVLKAFGV 432
A+ A GV
Sbjct: 413 ALKTAIGV 420
>sp|P05378|TRPE_THETH ANTHRANILATE SYNTHASE COMPONENT I >gi|77582|pir||S03316
anthranilate synthase (EC 4.1.3.27) component I -
Thermus aquaticus >gi|48263|emb|CAA30566.1| (X07744)
trpE polypeptide (AA 1-462) [Thermus thermophilus]
Length = 462
Score = 265 bits (670), Expect = 7e-70
Identities = 158/361 (43%), Positives = 210/361 (57%), Gaps = 21/361 (5%)
Query: 87 FLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPWVFI-------YNHGKGELRFYYLRDPS 139
F GG +GY AYD V Y +P G +F+ ++H K L +L P
Sbjct: 97 FFGGVVGYAAYDLVRYYERLPSLKPDDLGLPDLLFVEPEVVAVFDHLKNLL---HLVAPG 153
Query: 140 FDPETIVERAKREELKFEN----------GGAEIIRTDANREEFMEMVEKGKEYIFAGDV 189
DPE R E + + GG + D +RE ++E V + +YI AGD+
Sbjct: 154 RDPEEAEARLFWAERRLKGPLPGVPGERAGGRARFQADFSREAYLEAVRRALDYIRAGDI 213
Query: 190 FQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVR 248
FQVVLS V P LYR L S+NPSPY L+ ++ LV ASPE++ +GR V
Sbjct: 214 FQVVLSLRLSSPLTVHPFALYRALRSVNPSPYMGYLDLGEVVLVSASPESLLRSDGRRVV 273
Query: 249 INPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFF 308
PIAGT PRGK EED+ + LL DEKE AEHVML+DL+RND+ +V+ G+V+++
Sbjct: 274 TRPIAGTRPRGKDEEEDKRLAEELLRDEKEVAEHVMLLDLSRNDIGRVAAFGTVRVLEPL 333
Query: 309 DVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRV 368
V YSHV H+ S V G LA+ K DA+ + P GT++GAPKIRAMEII+ELE RR
Sbjct: 334 HVEHYSHVMHLVSTVEGILAEGKTPLDALASVLPMGTVSGAPKIRAMEIIEELEPHRRGP 393
Query: 369 YGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLK 428
YGG+ GY + G D A+ +R + HV+AGAGIVADS+PE+E+ E NK +A+LK
Sbjct: 394 YGGSFGYLAYDGAMDMALTLRTFVVAKGWMHVQAGAGIVADSVPEREYEECWNKARALLK 453
Query: 429 A 429
A
Sbjct: 454 A 454
>sp|Q06128|TRPE_SULSO ANTHRANILATE SYNTHASE COMPONENT I >gi|421727|pir||A40635
anthranilate synthase (EC 4.1.3.27) component I, TrpE -
Sulfolobus solfataricus >gi|7436735|pir||JC5323
anthranilate synthase (EC 4.1.3.27) component I
[validated] - Sulfolobus solfataricus
>gi|152937|gb|AAA73379.1| (M98048) anthranilate synthase
component I [Sulfolobus solfataricus]
>gi|1004323|emb|CAA90311.1| (Z50014) anthranilate
synthase component 1 [Sulfolobus solfataricus]
Length = 421
Score = 263 bits (666), Expect = 2e-69
Identities = 169/428 (39%), Positives = 240/428 (55%), Gaps = 26/428 (6%)
Query: 18 IREFENPF-IFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGK-KVSNETNPFLS-- 73
I EF +PF +F I +D K A L P++ S +G K+ ++ L+
Sbjct: 6 ISEFASPFEVFKCIERDFKVAGLLESIGGPQYKARYSVIAWSTNGYLKIHDDPVNILNGY 65
Query: 74 LKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW--------VFIYNH 125
LK + G F GG +GYI+YDAV + + +P+ +P+ + IY+H
Sbjct: 66 LKDLKLADIPGL-FKGGMIGYISYDAVRFWEKIRDLKPAAED-WPYAEFFTPDNIIIYDH 123
Query: 126 GKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIF 185
+G++ + D ++ E K N+ + +V + EYI
Sbjct: 124 NEGKVYV------NADLSSVGGCGDIGEFK-----VSFYDESLNKNSYERIVSESLEYIR 172
Query: 186 AGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEG 244
+G +FQVVLSR Y DP+ +Y L INPSPY F L+F +K L+G+SPE + V+
Sbjct: 173 SGYIFQVVLSRFYRYIFSGDPLRIYYNLRRINPSPYMFYLKFDEKYLIGSSPELLFRVQD 232
Query: 245 RTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKL 304
V PIAGT PRG EED ++ L++ EK++AEH+MLVDLARND+ KV PG+VK+
Sbjct: 233 NIVETYPIAGTRPRGADQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVKV 292
Query: 305 VRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKS 364
V KYSHVQHI S+VIG L + + + A+FPAGT++G PK AM II+ LE+
Sbjct: 293 PELMYVEKYSHVQHIVSKVIGTLKKKYNALNVLSATFPAGTVSGRPKPMAMNIIETLEEY 352
Query: 365 RRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMK 424
+R Y GA+G+ S G A+FAIAIR A + + AGAGIV DS PE E++ETE+K+K
Sbjct: 353 KRGPYAGAVGFISADGNAEFAIAIRTAFLNKELLRIHAGAGIVYDSNPESEYFETEHKLK 412
Query: 425 AVLKAFGV 432
A+ A GV
Sbjct: 413 ALKTAIGV 420
>sp|Q9Z4W7|TRPE_STRCO ANTHRANILATE SYNTHASE COMPONENT I >gi|7480465|pir||T36306 probable
anthranilate synthase component I - Streptomyces
coelicolor >gi|4490623|emb|CAB38585.1| (AL035654)
probable anthranilate synthase component I [Streptomyces
coelicolor A3(2)]
Length = 511
Score = 262 bits (662), Expect = 6e-69
Identities = 136/260 (52%), Positives = 176/260 (67%), Gaps = 2/260 (0%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFK--K 229
+F E V + +E+I AGD FQ+VLSR P +LYR L + NPSPY + L +
Sbjct: 244 QFTERVARAREHIAAGDAFQIVLSRRLSRPLRARPTDLYRHLRATNPSPYMYHLSLGGGR 303
Query: 230 ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLA 289
++GASPE + EGRTVR P+AGT PR P ED + R L +DEKERAEHVMLVDL
Sbjct: 304 HVIGASPELLVKAEGRTVRTRPLAGTRPRHPDPAEDLRLERELRADEKERAEHVMLVDLG 363
Query: 290 RNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGA 349
RND+ +V++PG+V++ R V ++SHV H+ S V G LA+ +D DA+ ++FPAGTL+GA
Sbjct: 364 RNDLGRVTEPGTVRVERLMRVERFSHVMHLSSTVRGRLAEGRDALDALRSAFPAGTLSGA 423
Query: 350 PKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVAD 409
PKIRAMEII ELE +R VYGGA+G+ G DFAIA+R + HV+AGAGIVAD
Sbjct: 424 PKIRAMEIIAELEPEQRGVYGGALGFVGADGLTDFAIALRTMVVADGHVHVQAGAGIVAD 483
Query: 410 SIPEKEFYETENKMKAVLKA 429
S P EF ET +K +A+L A
Sbjct: 484 SDPAAEFRETLHKSRAMLTA 503
>sp|P20579|TRPE_PSEPU ANTHRANILATE SYNTHASE COMPONENT I >gi|94874|pir||E35115
anthranilate synthase (EC 4.1.3.27) alpha chain -
Pseudomonas putida >gi|151629|gb|AAA80551.1| (M33799)
anthranilate synthetase alpha-subunit [Pseudomonas
putida]
Length = 493
Score = 261 bits (661), Expect = 8e-69
Identities = 172/472 (36%), Positives = 238/472 (49%), Gaps = 61/472 (12%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFL--DGKKVSNET 68
P+ +Y + + N ++ + K + + I + + G + DG +V +
Sbjct: 30 PLSIYLKLADQPNSYLLESVQGGEKWGRYSMIGLPSRTVMRVHGYHVSILHDGVEVESHD 89
Query: 69 --NPFLSLKSFN-----MDSASGSGFLGGFMGYIAYDAVHNYIE---GSIEEPSVFGY-- 116
+P ++SF D F GG +GY YD V Y+E G P G
Sbjct: 90 VEDPLAFVESFKDRYKVADIPGLPRFNGGLVGYFGYDCVR-YVEKRLGVSPNPDPLGVPD 148
Query: 117 -----YPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEI-------- 163
V ++++ G++ L DP+ EE FE G A +
Sbjct: 149 ILLMVSDAVVVFDNLAGKMHAIVLVDPA------------EEQAFEQGQARLQGLLETLR 196
Query: 164 --------------------IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSD 203
R+ RE++ V + KEYI AGD QVV S+ +
Sbjct: 197 QPITPRRGLDLSGPQAAEPEFRSSYTREDYENAVGRIKEYILAGDCMQVVPSQRMSIDFK 256
Query: 204 VDPVELYRKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTP 262
P++LYR L NP+PY + F +VG+SPE + VE V + PIAGT PRG T
Sbjct: 257 AAPIDLYRALRCFNPTPYMYFFNFGDFHVVGSSPEVLVRVEDNLVTVRPIAGTRPRGATE 316
Query: 263 EEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESE 322
E D + LLSD+KE AEH+ML+DL RNDV +VS GSV+L + +YS+V HI S
Sbjct: 317 EADRALEDDLLSDDKEIAEHLMLIDLGRNDVGRVSSTGSVRLTEKMVIERYSNVMHIVSN 376
Query: 323 VIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYA 382
V G+L + DA+ A PAGTL+GAPKIRAMEIIDELE +R VYGGA+GYF+ G
Sbjct: 377 VAGQLREGLTAMDALRAILPAGTLSGAPKIRAMEIIDELEPVKRGVYGGAVGYFAWNGNM 436
Query: 383 DFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
D AIAIR A I + HV+AG GIVADS+P E+ ET NK +A+ +A + +
Sbjct: 437 DTAIAIRTAVINDGELHVQAGGGIVADSVPALEWEETINKRRAMFRAVALAE 488
>sp|Q9X6J4|TRPE_BACST ANTHRANILATE SYNTHASE COMPONENT I
>gi|4928946|gb|AAD33791.1|AF139534_2 (AF139534)
anthranilate synthase subunit [Bacillus
stearothermophilus]
Length = 508
Score = 260 bits (658), Expect = 2e-68
Identities = 169/464 (36%), Positives = 247/464 (52%), Gaps = 44/464 (9%)
Query: 9 VEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGKKVSNET 68
+EP+++++ +RE E F+ +S A+ ++I +P T+E TFL + N
Sbjct: 30 IEPLQVFANLRE-EAVFLLESKDDESPWARYSFIGVAPFLTLESETGETFLIKDENGNVQ 88
Query: 69 NPFLSLKSFNM---------DSASGSGFLGGFMGYIAYDAV-------HNYIEGSIEEPS 112
+LK A + F GG +G++ YD + + +
Sbjct: 89 MTASTLKEAFQAVERALCVKPLAEAAPFTGGAVGFLGYDFISAIEKVPRHRAPDLAMKAG 148
Query: 113 VFGYYPWVFIYNHGKGELR-FYYLR---DPSFDPETIVERAKREELKFENGGAEIIRTDA 168
F + +F ++H K EL +Y+R + + + RA E + A R +
Sbjct: 149 HFVFCESLFAFDHEKRELSLIHYIRLKGHETMQEKIAIYRAAEERIAALAAKASRPRAEQ 208
Query: 169 ----------------------NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDP 206
+E+F+ VE K+YI AGDVFQ VLS+ + +
Sbjct: 209 PLLPAEDEAERAALFSKASSNYEKEQFLRDVEAVKQYIAAGDVFQAVLSQRFSVPVQAGG 268
Query: 207 VELYRKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEED 265
+YR L INPSPY F I +VG+SPE + V R I+PIAGT RG++P ED
Sbjct: 269 FAIYRILRHINPSPYMFYFRLDGIEIVGSSPEKLIQVRNRRAEIDPIAGTRRRGRSPAED 328
Query: 266 EEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIG 325
E++ L D KERAEH MLVDLARND+ +V+K G+V++ ++ K+SHV H+ S+V+G
Sbjct: 329 EKLADELYHDPKERAEHYMLVDLARNDIGRVAKYGTVEVPVLMEIGKFSHVMHLISKVVG 388
Query: 326 ELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFA 385
L DD DA+ A+FPAGT++GAPK+RAM+I+ ELE + R +Y GAI Y G D
Sbjct: 389 VLDDDIHPIDALLAAFPAGTVSGAPKVRAMQILQELEPTARGLYAGAIAYIGFDGSIDSC 448
Query: 386 IAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
IAIR A I+ A+V+AGAGIVADS+PE E+ ET NK A++ A
Sbjct: 449 IAIRTAVIKDGYAYVQAGAGIVADSVPELEWKETRNKASALIYA 492
>sp|Q02001|TRPE_LACLA ANTHRANILATE SYNTHASE COMPONENT I >gi|421417|pir||S35124
anthranilate synthase (EC 4.1.3.27) alpha chain -
Lactococcus lactis subsp. lactis
>gi|149516|gb|AAA25223.1| (M87483) anthranilate synthase
alpha subunit [Lactococcus lactis]
Length = 456
Score = 259 bits (655), Expect = 4e-68
Identities = 169/446 (37%), Positives = 250/446 (55%), Gaps = 26/446 (5%)
Query: 7 ERVEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGKKVSN 66
+ + PI +Y ++ +N I I +++ +++ + I+ +P ++ + ++ + +S+
Sbjct: 10 DTMTPISVYLRLKG-KNKVILESIPRENDQSRFSIIALNPVKHIKFTDGILSVNDEIISD 68
Query: 67 ETNPFLSLKSF---------NMDSASGSGFLG--GFMGYIAYDAVHNYIEGSIEEPSV-F 114
E NP L+ N+D SG +G GF Y ++ + ++ SI P + F
Sbjct: 69 E-NPMEFLEKLVCQPESTDENLDLPFTSGAIGYAGFDTYGIFEGIQPELKDSIGTPDMYF 127
Query: 115 GYYPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKF-------ENGGAEIIR-- 165
Y I++H + +L F S E ++ A ++ EN E+ +
Sbjct: 128 MLYESALIFDHKREKLIFIEDNTYSQRSEKELQNALYRNIESLSLLTEAENELTELSKLN 187
Query: 166 --TDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
++ ++E F E V K KE I GD+FQVVLS+ +P YRKL NPS Y +
Sbjct: 188 FVSNMSQELFEEKVAKAKELIRNGDMFQVVLSQRLTADFTDNPFNYYRKLRVENPSSYMY 247
Query: 224 ILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEH 282
+EF ++G+SPE + +V G V NPIAGT RG+T ED+ + L SD KE AEH
Sbjct: 248 FMEFDNFHVIGSSPERLVAVHGNQVSTNPIAGTRKRGQTEFEDQALIEDLESDPKEVAEH 307
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
MLVDL RND+ K+SK GS+++ F V KY +V HI SEV GEL + DA+ A+ P
Sbjct: 308 KMLVDLGRNDIGKISKYGSIEVPVFMKVEKYRYVMHITSEVTGELRPEFTAMDALRATLP 367
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
AGTL+GAPK RA + I E E +R +YGGAIGY + G DFAIAIR ++ +KAHV+A
Sbjct: 368 AGTLSGAPKHRAYQRIYEFETQKRGIYGGAIGYLTKNGNCDFAIAIRTMVLKDKKAHVQA 427
Query: 403 GAGIVADSIPEKEFYETENKMKAVLK 428
GAGIV DS+PE E+ ET NK + +LK
Sbjct: 428 GAGIVYDSVPEHEYQETLNKAQGLLK 453
>sp|P30526|TRPE_BACCA ANTHRANILATE SYNTHASE COMPONENT I >gi|478584|pir||S19266
anthranilate synthase (EC 4.1.3.27) component I -
Bacillus caldotenax >gi|48785|emb|CAA39230.1| (X55703)
anthranilate synthase [Bacillus caldotenax]
Length = 508
Score = 259 bits (654), Expect = 6e-68
Identities = 171/465 (36%), Positives = 253/465 (53%), Gaps = 46/465 (9%)
Query: 9 VEPIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGKKVSNET 68
+EP+ +++ +RE E F+ +S A+ ++I +P T+E TF + NE
Sbjct: 30 IEPLGVFANLRE-EAVFLLESKDDESPWARYSFIGVAPFLTLESETGETFSVKDENGNEQ 88
Query: 69 NPFLSLKSFNM---------DSASGSGFLGGFMGYIAYDAVHNYIEG-----SIEEPSVF 114
+LK A F GG +G++ YD + + IE + + P
Sbjct: 89 ITAPTLKEAFQWVERTLAVKPLAETVPFTGGAVGFLGYDFI-SAIEKVPRHKNRDVPMKT 147
Query: 115 GYYPW---VFIYNHGKGELR-FYYLR-DPSFDPETIVERAKREELKFENGGAEIIRTDA- 168
Y+ + +F ++ K EL +Y+R + E +E + E + + A+ R A
Sbjct: 148 AYFVFCESLFAFDQKKRELLVIHYIRLSGNETEEEKIEAYRAAERRMADLAAKAARPQAE 207
Query: 169 -----------------------NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVD 205
++++F+ VE K YI AGDVFQ VLS+ + +
Sbjct: 208 QPLLPAESESGRTASFAKAVSNYDKKQFLRDVEAVKRYIAAGDVFQAVLSQRFCVPVQAG 267
Query: 206 PVELYRKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEE 264
+YR L INPSPY F + + +VG+SPE + V R V I+PIAGT RG++PEE
Sbjct: 268 GFAIYRLLRYINPSPYMFYFQLDGVEIVGSSPEKLIQVHRRRVEIDPIAGTRRRGRSPEE 327
Query: 265 DEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVI 324
DE + L D KERAEH MLVDLARND+ +V+K G+V++ + K+SHV H+ S+V+
Sbjct: 328 DERLADELYHDPKERAEHYMLVDLARNDIGRVAKYGTVEVPVLLQIGKFSHVMHLISKVV 387
Query: 325 GELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADF 384
GEL D+ DA+ A+FPAGT++GAPK+RAM+I+ ELE + R +Y GAI Y G D
Sbjct: 388 GELDDNVHPIDALLAAFPAGTVSGAPKVRAMQILQELEPTARGLYAGAIAYIGFDGNIDS 447
Query: 385 AIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
IAIR A ++ A+V+AGAGIVADS+PE E+ ET NK A++ A
Sbjct: 448 CIAIRTAVVKDGYAYVQAGAGIVADSVPELEWKETRNKASALMNA 492
>sp|P18267|TRPE_BACPU ANTHRANILATE SYNTHASE COMPONENT I
Length = 513
Score = 256 bits (647), Expect = 4e-67
Identities = 154/376 (40%), Positives = 212/376 (55%), Gaps = 35/376 (9%)
Query: 87 FLGGFMGYIAYDAVHNYIE-------GSIEEPSVFGYYPWVFIYNHGKGELRFY-YLRDP 138
F GG +GY++YD + +IE + P + ++H + F Y +
Sbjct: 116 FTGGAVGYLSYDLIPTLTSVRPHRSASTIENAHIC--LPTMIAFDHETNHVHFIQYTQLT 173
Query: 139 SFDPETIVERAKREELKF------------------------ENGGAEIIRTDANREEFM 174
+ E RA +E+ K E E + + + +F+
Sbjct: 174 GHETEDEKIRAYKEKQKQLEQMIHKLHSKVDMKELILSGNMNEPPSFEHVTSTYEKAQFL 233
Query: 175 EMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFK-KILVG 233
+ VEK KEYI AGD+FQ VLS+ + + V ELYR L +NPSPY + ++ K + LVG
Sbjct: 234 KDVEKIKEYIRAGDIFQGVLSQRFDIPVSVSSFELYRVLRIVNPSPYMYFMKLKDRDLVG 293
Query: 234 ASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDV 293
+SPE + + + I+PIAGT RG T EED E+ R LL DEKE+AEH MLVDLARNDV
Sbjct: 294 SSPERLIHAKNGHLEIHPIAGTRKRGTTREEDAELARELLEDEKEKAEHYMLVDLARNDV 353
Query: 294 RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIR 353
+V++ GSV + F V+ +SHV HI S V G+L D DA+ ++FPAGTLTGAPKIR
Sbjct: 354 GRVAEYGSVSVPTFTKVVNFSHVMHIISIVTGKLKRDTHPVDALMSAFPAGTLTGAPKIR 413
Query: 354 AMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPE 413
AM++++E+E R YGG I Y G D I IR ++ A ++AGAGIVADS+PE
Sbjct: 414 AMQLLNEMEPEPRETYGGCIAYIGFDGNIDSCITIRTMSVKNHTASIQAGAGIVADSVPE 473
Query: 414 KEFYETENKMKAVLKA 429
E+ ET NK A+LKA
Sbjct: 474 NEWEETCNKAGALLKA 489
>pir||JH0098 anthranilate synthase (EC 4.1.3.27) component I - Bacillus pumilus
(fragment) >gi|143779|gb|AAB02272.1| (M36468)
anthranilate synthase [Bacillus pumilus]
Length = 512
Score = 256 bits (647), Expect = 4e-67
Identities = 154/376 (40%), Positives = 212/376 (55%), Gaps = 35/376 (9%)
Query: 87 FLGGFMGYIAYDAVHNYIE-------GSIEEPSVFGYYPWVFIYNHGKGELRFY-YLRDP 138
F GG +GY++YD + +IE + P + ++H + F Y +
Sbjct: 115 FTGGAVGYLSYDLIPTLTSVRPHRSASTIENAHIC--LPTMIAFDHETNHVHFIQYTQLT 172
Query: 139 SFDPETIVERAKREELKF------------------------ENGGAEIIRTDANREEFM 174
+ E RA +E+ K E E + + + +F+
Sbjct: 173 GHETEDEKIRAYKEKQKQLEQMIHKLHSKVDMKELILSGNMNEPPSFEHVTSTYEKAQFL 232
Query: 175 EMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFK-KILVG 233
+ VEK KEYI AGD+FQ VLS+ + + V ELYR L +NPSPY + ++ K + LVG
Sbjct: 233 KDVEKIKEYIRAGDIFQGVLSQRFDIPVSVSSFELYRVLRIVNPSPYMYFMKLKDRDLVG 292
Query: 234 ASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDV 293
+SPE + + + I+PIAGT RG T EED E+ R LL DEKE+AEH MLVDLARNDV
Sbjct: 293 SSPERLIHAKNGHLEIHPIAGTRKRGTTREEDAELARELLEDEKEKAEHYMLVDLARNDV 352
Query: 294 RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIR 353
+V++ GSV + F V+ +SHV HI S V G+L D DA+ ++FPAGTLTGAPKIR
Sbjct: 353 GRVAEYGSVSVPTFTKVVNFSHVMHIISIVTGKLKRDTHPVDALMSAFPAGTLTGAPKIR 412
Query: 354 AMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPE 413
AM++++E+E R YGG I Y G D I IR ++ A ++AGAGIVADS+PE
Sbjct: 413 AMQLLNEMEPEPRETYGGCIAYIGFDGNIDSCITIRTMSVKNHTASIQAGAGIVADSVPE 472
Query: 414 KEFYETENKMKAVLKA 429
E+ ET NK A+LKA
Sbjct: 473 NEWEETCNKAGALLKA 488
>pir||T46852 anthranilate synthase (EC 4.1.3.27) component I [similarity] -
Rhodobacter sphaeroides >gi|4185544|gb|AAD09116.1|
(AF108766) anthranilate synthase component I
[Rhodobacter sphaeroides]
Length = 503
Score = 256 bits (647), Expect = 4e-67
Identities = 130/267 (48%), Positives = 177/267 (65%), Gaps = 1/267 (0%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+R++ E + VEK K+YI AGD+FQVV S+ + + P LYR L NPSP+ F
Sbjct: 223 MRSNFTHEGYKAAVEKAKDYIRAGDIFQVVPSQRWAQDFRLPPFALYRSLRKTNPSPFMF 282
Query: 224 ILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEH 282
F +VGASPE + + R V + PIAGT RG TPEED + LLSD+KE AEH
Sbjct: 283 FFNFGGFQVVGASPEILVRLRDREVTVRPIAGTRKRGATPEEDRALEADLLSDKKELAEH 342
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+ML+DL RNDV +V+K G+V+ F + +YSHV HI S V+GE+A+ +D A+ A P
Sbjct: 343 LMLLDLGRNDVGRVAKIGTVRPTEKFIIERYSHVMHIVSNVVGEIAEGEDALSALLAGLP 402
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
AGT++GAPK+RAMEIIDELE +R VYGG +GYF+ G DF IA+R A ++ ++++
Sbjct: 403 AGTVSGAPKVRAMEIIDELEPEKRGVYGGGVGYFAANGEMDFCIALRTAVLKDETLYIQS 462
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
G G+V DS PE E+ ET NK +A+ +A
Sbjct: 463 GGGVVYDSDPEAEYQETVNKARALRRA 489
>sp|P20580|TRPE_PSEAE ANTHRANILATE SYNTHASE COMPONENT I >gi|94755|pir||D35114
anthranilate synthase (EC 4.1.3.27) alpha chain
[imported] - Pseudomonas aeruginosa
>gi|11347435|pir||C83569 anthranilate synthetase
component I PA0609 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|5725146|dbj|BAA83144.1| (AB030825)
anthranilate synthetase component 1 [Pseudomonas
aeruginosa] >gi|9946483|gb|AAG03998.1|AE004497_5
(AE004497) anthranilate synthetase component I
[Pseudomonas aeruginosa]
Length = 492
Score = 256 bits (646), Expect = 5e-67
Identities = 154/375 (41%), Positives = 211/375 (56%), Gaps = 28/375 (7%)
Query: 87 FLGGFMGYIAYDAVHNYIE---GSIEEPSVFG-------YYPWVFIYNHGKGELRFYYLR 136
F GG +GY YD V Y+E + P G V ++++ G++ L
Sbjct: 115 FDGGLVGYFGYDCVR-YVEKRLATCPNPDPLGNPDILLMVSDAVVVFDNLAGKIHAIVLA 173
Query: 137 DPSFDP---------ETIVERAKRE-------ELKFENGGAEIIRTDANREEFMEMVEKG 180
DPS + E ++ER ++ +L+ G R RE++ V +
Sbjct: 174 DPSEENAYERGQARLEELLERLRQPITPRRGLDLEAAQGREPAFRASFTREDYENAVGRI 233
Query: 181 KEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPETM 239
K+YI AGD QVV S+ + P++LYR L NP+PY + F +VG+SPE +
Sbjct: 234 KDYILAGDCMQVVPSQRMSIEFKAAPIDLYRALRCFNPTPYMYFFNFGDFHVVGSSPEVL 293
Query: 240 GSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKP 299
VE V + PIAGT PRG E D + + LLSD KE AEH+ML+DL RNDV +VS
Sbjct: 294 VRVEDGLVTVRPIAGTRPRGINEEADLALEQDLLSDAKEIAEHLMLIDLGRNDVGRVSDI 353
Query: 300 GSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIID 359
G+VK+ + +YS+V HI S V G+L + DA+ A PAGTL+GAPKIRAMEIID
Sbjct: 354 GAVKVTEKMVIERYSNVMHIVSNVTGQLREGLSAMDALRAILPAGTLSGAPKIRAMEIID 413
Query: 360 ELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYET 419
ELE +R VYGGA+GY + G D AIAIR A I+ + HV+AG GIVADS+P E+ ET
Sbjct: 414 ELEPVKRGVYGGAVGYLAWNGNMDTAIAIRTAVIKNGELHVQAGGGIVADSVPALEWEET 473
Query: 420 ENKMKAVLKAFGVIQ 434
NK +A+ +A + +
Sbjct: 474 INKRRAMFRAVALAE 488
>sp|P20463|TRPE_LEPBI ANTHRANILATE SYNTHASE COMPONENT I >gi|94610|pir||B32840
anthranilate synthase (EC 4.1.3.27) component I -
Leptospira biflexa >gi|149628|gb|AAA88216.1| (M22468)
anthranilate synthase component 1 [Leptospira biflexa]
Length = 462
Score = 255 bits (645), Expect = 6e-67
Identities = 157/435 (36%), Positives = 247/435 (56%), Gaps = 14/435 (3%)
Query: 7 ERVEPIKLYSVIR-EFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGKGTFLDGKKVS 65
E +E +L+ VI ++EN F+ G + +++ + I P + +DGKK
Sbjct: 23 EGIEFWELFRVIEAKYENCFLLESAGDNQYDSRYSVIGFQPSHLILGEPGILEIDGKKYP 82
Query: 66 NETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIE-------EPSVFGYYP 118
E NP+ +L+ ++ + GGF+GY+ Y ++ + E ++ +FG Y
Sbjct: 83 VE-NPYFALRELTDYNSLSISYAGGFVGYLGYQSMQ-FFEPKLQLKPHPDFPAMIFGLYL 140
Query: 119 WVFIYNHGKGELRFYYL-RDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMV 177
IY+ GEL ++ + + I+E+ K+E + +++ ++E +MV
Sbjct: 141 DGLIYDKFTGELIYFDNGTNRIHEVNQILEQLKKENSQKPKATVSLVKAGLSKEVHKQMV 200
Query: 178 EKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASP 236
E+ E + AG+ FQ + E + + D +P+ +Y L INPSP+ + + + + ++GASP
Sbjct: 201 EEALEEVKAGNTFQCQIGFEEIYQVDGNPLAIYETLREINPSPHMYYVNLELVTILGASP 260
Query: 237 ETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKV 296
++ + + P+AGT RG +ED + R+LL+D KE AEH ML+DL RNDV +V
Sbjct: 261 SSLFRLRQGEMESFPLAGTTKRGVDAKEDTLLARKLLTDPKEIAEHNMLIDLHRNDVGRV 320
Query: 297 SKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRA-M 355
+K G+VK+ R FDV ++SHVQHI SEV+G L+ +DMF + +SFP GTL+GAPKI +
Sbjct: 321 AKFGTVKVRRRFDVKRFSHVQHISSEVVGILSSKEDMFSGLASSFPRGTLSGAPKIESDS 380
Query: 356 EIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSI-PEK 414
+II+ +EKS R YGGA+G F + G FAI IR + G+K VRA GIV I PE
Sbjct: 381 KIIERIEKSPRGPYGGAVGSFGLNGDCTFAIPIRSFFVNGKKGFVRASGGIVFGFIEPED 440
Query: 415 EFYETENKMKAVLKA 429
E+ E NKM +V KA
Sbjct: 441 EYQEIINKMASVRKA 455
>pir||T01990 anthranilate synthase (EC 4.1.3.27) alpha-2 chain - common tobacco
>gi|3348124|gb|AAC27795.1| (AF079168)
feedback-insensitive anthranilate synthase alpha-2 chain
[Nicotiana tabacum]
Length = 616
Score = 255 bits (645), Expect = 6e-67
Identities = 156/402 (38%), Positives = 226/402 (55%), Gaps = 55/402 (13%)
Query: 87 FLGGFMGYIAYDAVHNYIEGS----IEEPS--------VFGYYPWVFIYNHGKGE---LR 131
F GG++GY +YD V Y+E + P G Y V +++H + + +
Sbjct: 174 FCGGWVGYFSYDTVR-YVENRKLPFLRAPEDDRNLADIQLGLYEDVIVFDHVEKKAHVIH 232
Query: 132 FYYLRDPSFDPETIVERAKREEL-----------KFENG---------GAEIIRTDANRE 171
+ L S PE ++ KR E+ + G G + + + E
Sbjct: 233 WVQLDQYSSLPEAYLDGKKRLEILVSRVQGIESPRLSPGSVDFCTHAFGPSLTKGNMTSE 292
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY-TFILEFKKI 230
E+ V + KE+I AGD+FQ+VLS+ + R+ DP E+YR L +NPSPY T+I I
Sbjct: 293 EYKNAVLQAKEHIAAGDIFQIVLSQRFERRTFADPFEVYRALRIVNPSPYMTYIQARGCI 352
Query: 231 LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLAR 290
LV +SPE + V+ R + P+AGT+ RGKTP+ED + ++L DEK+RAEH+MLVDL R
Sbjct: 353 LVASSPEILTRVKKRRIVNRPLAGTSRRGKTPDEDVMLEMQMLKDEKQRAEHIMLVDLGR 412
Query: 291 NDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAP 350
NDV KVSKPGSV + + V +YSHV HI S V GEL D +DA+ A+ P GT++GAP
Sbjct: 413 NDVGKVSKPGSVNVEKLMSVERYSHVMHISSTVSGELLDHLTCWDALRAALPVGTVSGAP 472
Query: 351 KIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIR-MAEIEGRK------------ 397
K++AME+ID+LE +RR Y G G S +G D A+A+R M + G +
Sbjct: 473 KVKAMELIDQLEVARRGPYSGGFGGISFSGDMDIALALRTMVFLNGARYDTMYSYTDASK 532
Query: 398 -----AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
AH+++GAGIVADS P++E E ENK+ + +A + +
Sbjct: 533 RQEWVAHLQSGAGIVADSNPDEEQIECENKVAGLCRAIDLAE 574
>sp|P95646|TRPE_RHOSH ANTHRANILATE SYNTHASE COMPONENT I >gi|1835208|emb|CAA70293.1|
(Y09072) anthranilate synthase (component I)
[Rhodobacter sphaeroides]
Length = 500
Score = 255 bits (644), Expect = 8e-67
Identities = 129/267 (48%), Positives = 177/267 (65%), Gaps = 1/267 (0%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+R++ E + VEK K+YI AGD+FQVV S+ + + P LYR L NPSP+ F
Sbjct: 220 MRSNFTHEGYKAAVEKAKDYIRAGDIFQVVPSQRWAQDFRLPPFALYRSLRKTNPSPFMF 279
Query: 224 ILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEH 282
F +VGASPE + + R V + PIAGT RG TPEED + LLSD+KE AEH
Sbjct: 280 FFNFGGFQVVGASPEILVRLRDREVTVRPIAGTRKRGATPEEDRALEADLLSDKKELAEH 339
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+ML+DL RNDV +V+K G+V+ F + +YSHV HI S ++GE+A+ +D A+ A P
Sbjct: 340 LMLLDLGRNDVGRVAKIGTVRPTEKFIIERYSHVMHIVSNLVGEIAEGEDALSALLAGLP 399
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
AGT++GAPK+RAMEIIDELE +R VYGG +GYF+ G DF IA+R A ++ ++++
Sbjct: 400 AGTVSGAPKVRAMEIIDELEPEKRGVYGGGVGYFAANGEMDFCIALRTAVLKDETLYIQS 459
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
G G+V DS PE E+ ET NK +A+ +A
Sbjct: 460 GGGVVYDSDPEAEYQETVNKARALRRA 486
>sp|P32069|TRPX_ARATH ANTHRANILATE SYNTHASE COMPONENT I-2 PRECURSOR
>gi|282854|pir||S27752 anthranilate synthase (EC
4.1.3.27) alpha chain - Arabidopsis thaliana
>gi|166606|gb|AAA32739.1| (M92354) anthranilate synthase
alpha subunit [Arabidopsis thaliana]
>gi|3582331|gb|AAC35228.1| (AC005496) anthranilate
synthase, alpha subunit [Arabidopsis thaliana]
Length = 621
Score = 254 bits (643), Expect = 1e-66
Identities = 171/481 (35%), Positives = 247/481 (50%), Gaps = 75/481 (15%)
Query: 25 FIFTIIGKDSKEAKL---TYISASPEFTVEISGKG---TFLD---GKKVSNETNPFLSLK 75
F+F + S+ + + + + A P T+EI KG T +D + E + + +
Sbjct: 126 FLFESVEPGSQSSNIGRYSVVGAQP--TIEIVAKGNVVTVMDHGASLRTEEEVDDPMMVP 183
Query: 76 SFNMDSASGSG-------FLGGFMGYIAYDAVH----------NYIEGSIEEPSV-FGYY 117
M+ + G F GG++GY +YD V N E P V G Y
Sbjct: 184 QKIMEEWNPQGIDELPEAFCGGWVGYFSYDTVRYVEKKKLPFSNAPEDDRSLPDVNLGLY 243
Query: 118 PWVFIYNHGKGELRFYYLRDPSFDPETIVERAKRE------------------------- 152
V +++H E + Y + D + VE RE
Sbjct: 244 DDVIVFDHV--EKKAYVIHWVRIDKDRSVEENFREGMNRLESLTSRIQDQKPPKMPTGFI 301
Query: 153 ELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRK 212
+L+ + G ++ ++ E + E V + KE+I AGD+FQ+VLS+ + R+ DP E+YR
Sbjct: 302 KLRTQLFGPKLEKSTMTSEAYKEAVVEAKEHILAGDIFQIVLSQRFERRTFADPFEIYRA 361
Query: 213 LISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRR 271
L +NPSPY L+ + ILV +SPE + + R + P+AGT RGKTP+ED + +
Sbjct: 362 LRIVNPSPYMAYLQVRGCILVASSPEILLRSKNRKITNRPLAGTVRRGKTPKEDLMLEKE 421
Query: 272 LLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDK 331
LLSDEK+ AEH+MLVDL RNDV KVSKPGSV++ + D+ +SHV HI S V+GEL D
Sbjct: 422 LLSDEKQCAEHIMLVDLGRNDVGKVSKPGSVEVKKLKDIEWFSHVMHISSTVVGELLDHL 481
Query: 332 DMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMA 391
+DA+ A P GT++GAPK++AME+IDELE +RR Y G G S G D A+A+R
Sbjct: 482 TSWDALRAVLPVGTVSGAPKVKAMELIDELEVTRRGPYSGGFGGISFNGDMDIALALRTM 541
Query: 392 EIEGRK------------------AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVI 433
AH++AGAGIVADS P+ E E ENK A+ +A +
Sbjct: 542 VFPTNTRYDTLYSYKHPQRRREWIAHIQAGAGIVADSNPDDEHRECENKAAALARAIDLA 601
Query: 434 Q 434
+
Sbjct: 602 E 602
>sp|Q9XAZ0|TRPE_NEIMA ANTHRANILATE SYNTHASE COMPONENT I >gi|11268487|pir||G81892
anthranilate synthase (EC 4.1.3.27) chain I NMA1247
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|5051452|emb|CAB44973.1| (AJ242841) putative
anthranilate synthase component I [Neisseria
meningitidis] >gi|7379929|emb|CAB84502.1| (AL162755)
putative anthranilate synthase component I [Neisseria
meningitidis Z2491]
Length = 491
Score = 254 bits (641), Expect = 2e-66
Identities = 163/456 (35%), Positives = 244/456 (52%), Gaps = 32/456 (7%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGK--GTFLDGKKVS-NE 67
P+ LY + ++ + + + ++I ++ SGK + +G+ V ++
Sbjct: 31 PLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHD 90
Query: 68 TNPFLSLKSFNM-----DSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW--- 119
NP +++F+ + S F GG +GY Y+ ++N+ + + P
Sbjct: 91 GNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTP 150
Query: 120 ---------VFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEII------ 164
+ + ++ G++ DPS R + E+++ + + I
Sbjct: 151 DILLMLSQELAVIDNLSGKIHLVVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGS 210
Query: 165 -RTDA----NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPS 219
T+A E F V K K+YIFAGD QVV S+ + P+ LYR L ++NPS
Sbjct: 211 KHTEAVSEFGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSPLALYRALRTLNPS 270
Query: 220 PYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKE 278
PY F +F +VG+SPE + E V + PIAGT RGKTP ED + LLSD KE
Sbjct: 271 PYLFYYDFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKE 330
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
AEHVML+DL RNDV ++SK G VK+ + KYSHV HI S V G L D D +
Sbjct: 331 IAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILA 390
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
A+FPAGTL+GAPK+RAMEII+E+E S+R +YGGA+G + D AIAIR A ++
Sbjct: 391 ATFPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTL 450
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
+V++GAG+VADS P E+ ET+NK +AV++A ++Q
Sbjct: 451 YVQSGAGVVADSDPASEWQETQNKARAVIRAAQMVQ 486
>sp|P56995|TRPE_NEIMB ANTHRANILATE SYNTHASE COMPONENT I >gi|11268488|pir||E81132
anthranilate synthase component I NMB1021 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226260|gb|AAF41421.1| (AE002452) anthranilate
synthase component I [Neisseria meningitidis MC58]
Length = 491
Score = 253 bits (640), Expect = 2e-66
Identities = 163/456 (35%), Positives = 243/456 (52%), Gaps = 32/456 (7%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGK--GTFLDGKKVS-NE 67
P+ LY + ++ + + + ++I ++ SGK + +G+ V ++
Sbjct: 31 PLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHD 90
Query: 68 TNPFLSLKSFNM-----DSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW--- 119
NP +++F+ + S F GG +GY Y+ ++N+ + + P
Sbjct: 91 GNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTP 150
Query: 120 ---------VFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEII------ 164
+ + ++ G++ DPS R + E+++ + + I
Sbjct: 151 DILLMLSQELAVIDNLSGKIHLVVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGS 210
Query: 165 -RTDA----NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPS 219
T+A E F V K K+YIFAGD QVV S+ + P+ LYR L ++NPS
Sbjct: 211 KHTEAVSEFGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSPLALYRALRTLNPS 270
Query: 220 PYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKE 278
PY F +F +VG+SPE + E V + PIAGT RGKTP ED + LLSD KE
Sbjct: 271 PYLFYYDFGDFHIVGSSPEILVRRERNDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKE 330
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
AEHVML+DL RNDV ++SK G VK+ + KYSHV HI S V G L D D +
Sbjct: 331 IAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILA 390
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
A+FPAGTL+GAPK+RAMEII+E+E S+R +YGGA+G + D AIAIR A ++
Sbjct: 391 ATFPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTL 450
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
+V++GAG+VADS P E+ ET+NK +AV+ A ++Q
Sbjct: 451 YVQSGAGVVADSDPASEWQETQNKARAVIHAAQMVQ 486
>pir||E75353 anthranilate synthase component I - Deinococcus radiodurans
(strain R1) >gi|6459566|gb|AAF11345.1|AE002020_4
(AE002020) anthranilate synthase component I
[Deinococcus radiodurans]
Length = 473
Score = 252 bits (638), Expect = 4e-66
Identities = 162/400 (40%), Positives = 221/400 (54%), Gaps = 24/400 (6%)
Query: 50 VEISGKGTFLDGKKVSNETNPFLSLKSFN---MDSASG-SGFLGGFMGYIAYDAVHNYIE 105
V+ SG+ DG+ E +P L +D +G +GG +GY AYD + Y +
Sbjct: 70 VQSSGQFGDFDGE----EADPLARLYRVTTRPLDVPAGLPALVGGAVGYAAYDIIRAYEK 125
Query: 106 GSIEEP-------SVFGYYPWVFIYNHGKGELRFYYLRDPSFDPETIVERAK---REELK 155
P ++F + I++H K L + + VER R L
Sbjct: 126 LPDANPDELKLPDALFVAPRGLVIFDHLKHRLVVVAAAEEQAQADAEVERLLTRLRGPLP 185
Query: 156 FENG----GAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLR-SDVDPVELY 210
G A R++ E+ME V +GKEY+ AGD+FQ V S+ + D+ P LY
Sbjct: 186 EVPGQTPTAAPEFRSNFTPAEYMEAVRRGKEYVHAGDIFQFVPSQRFSAELGDLHPFALY 245
Query: 211 RKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIR 269
R L +NPSPY L ++ LV +SPE++ +G +V PIAGT RG T ED+ +
Sbjct: 246 RALRRVNPSPYLGYLALGEVTLVASSPESLLRSDGVSVVTRPIAGTRKRGATEAEDDALA 305
Query: 270 RRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELAD 329
LL+DEKERAEH+MLVDL RND+ KVS G+VK+ F + +YSHV HI S V GEL +
Sbjct: 306 AELLADEKERAEHLMLVDLGRNDIGKVSAYGTVKVENAFSIERYSHVMHIVSGVRGELRE 365
Query: 330 DKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIR 389
+ A+ + P GT++GAPKIRAMEIIDELE RR YGG GY + G D A+ +R
Sbjct: 366 GQTPLHALASVLPMGTVSGAPKIRAMEIIDELEPVRRGPYGGCFGYVAFDGSLDMALTLR 425
Query: 390 MAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
I K H++AGAG+VADS+PE E ET NK A+++A
Sbjct: 426 TMVIANGKVHIQAGAGVVADSVPELEEQETRNKAAALMRA 465
>gb|AAA74900.1| (L34343) anthranilate synthase alpha subunit [Ruta graveolens]
Length = 608
Score = 252 bits (637), Expect = 6e-66
Identities = 158/404 (39%), Positives = 221/404 (54%), Gaps = 59/404 (14%)
Query: 87 FLGGFMGYIAYDAVHNYIE---------------------GSIEEPSVFGYYP------- 118
F GG++GY +YD V Y+E G ++ VF +
Sbjct: 202 FCGGWVGYFSYDTVR-YVEKKKLPFFSAPTDDRNLPDVHLGLYDDVIVFDHVEKKAFVIH 260
Query: 119 WVFI---------YNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDAN 169
WV + YN G L R P + R+ +L + G ++ R+
Sbjct: 261 WVRLDQYSSVAEAYNDGMNRLENLVSRVHDIVPPKL--RSGSIKLHTRHFGPKLERSSMT 318
Query: 170 REEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK 229
E + E V + KE+I AGD+FQ+VLS+ + R+ DP E+YR L +NPSPY L+ +
Sbjct: 319 SEAYKEAVLEAKEHILAGDIFQIVLSQRFERRTFADPFEIYRSLRIVNPSPYMTYLQARG 378
Query: 230 -ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDL 288
ILV +SPE + V+ R + P+AGT RGKT +ED + LL+DEK+ AEH+MLVDL
Sbjct: 379 CILVASSPEILTRVKKRKITNRPLAGTIRRGKTRKEDLVFEKELLNDEKQCAEHIMLVDL 438
Query: 289 ARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTG 348
RNDV KVS+PGSVK+ + ++ YSHV HI S V GEL D +DA+ A+ P GT++G
Sbjct: 439 GRNDVGKVSEPGSVKVEKLMNIEHYSHVMHISSTVTGELLDHLTSWDALRAALPVGTVSG 498
Query: 349 APKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIR---------------MAEI 393
APK++AMEIID+LE +RR YGG G S TG D A+A+R ++
Sbjct: 499 APKVKAMEIIDKLEVTRRGPYGGGFGGISFTGDLDIALALRTMVFQTATRYDTMYSYKDV 558
Query: 394 EGRK---AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
+ R+ AH++AGAGIVADS P E E ENK A+ +A + +
Sbjct: 559 DKRREWIAHLQAGAGIVADSDPADEQRECENKAAALARAIDLAE 602
>pir||JQ1685 anthranilate synthase (EC 4.1.3.27) alpha-2 chain - Arabidopsis
thaliana
Length = 621
Score = 251 bits (635), Expect = 9e-66
Identities = 170/481 (35%), Positives = 246/481 (50%), Gaps = 75/481 (15%)
Query: 25 FIFTIIGKDSKEAKL---TYISASPEFTVEISGKG---TFLD---GKKVSNETNPFLSLK 75
F+F + S+ + + + + A P T+EI KG T +D + E + + +
Sbjct: 126 FLFESVEPGSQSSNIGRYSVVGAQP--TIEIVAKGNVVTVMDHGASLRTEEEVDDPMMVP 183
Query: 76 SFNMDSASGSG-------FLGGFMGYIAYDAVH----------NYIEGSIEEPSV-FGYY 117
M+ + G F GG++GY +YD V N E P V G Y
Sbjct: 184 QKIMEEWNPQGIDELPEAFCGGWVGYFSYDTVRYVEKKKLPFSNAPEDDRSLPDVNLGLY 243
Query: 118 PWVFIYNHGKGELRFYYLRDPSFDPETIVERAKRE------------------------- 152
V +++H E + Y + D + VE RE
Sbjct: 244 DDVIVFDHV--EKKAYVIHWVRIDKDRSVEENFREGMNRLESLTSRIQDQKPPKMPTGFI 301
Query: 153 ELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRK 212
+L+ + G ++ ++ E + E V + KE+I AGD+FQ+VLS+ + R+ DP E+YR
Sbjct: 302 KLRTQLFGPKLEKSTMTSEAYKEAVVEAKEHILAGDIFQIVLSQRFERRTFADPFEIYRA 361
Query: 213 LISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRR 271
L +NPSPY L+ + ILV +SPE + + R + P+AGT RGKTP+ED + +
Sbjct: 362 LRIVNPSPYMAYLQVRGCILVASSPEILLRSKNRKITNRPLAGTVRRGKTPKEDLMLEKE 421
Query: 272 LLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDK 331
LLSDEK+ AEH+MLVDL RNDV KVSKPGSV++ + D+ +SHV HI S V+GEL D
Sbjct: 422 LLSDEKQCAEHIMLVDLGRNDVGKVSKPGSVEVKKLKDIEWFSHVMHISSTVVGELLDHL 481
Query: 332 DMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMA 391
+DA+ A P GT++GAPK++AME+IDELE +RR Y G G S G D A+A+R
Sbjct: 482 TSWDALRAVLPVGTVSGAPKVKAMELIDELEVTRRGPYSGGFGGISFNGDMDIALALRTM 541
Query: 392 EIEGRK------------------AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVI 433
AH++AGAGIVADS P+ E E NK A+ +A +
Sbjct: 542 VFPTNTRYDTLYSYKHPQRRREWIAHIQAGAGIVADSNPDDEHRECFNKAAALARAIDLA 601
Query: 434 Q 434
+
Sbjct: 602 E 602
>pir||A82835 anthranilate synthase component I XF0210 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9105014|gb|AAF83023.1|AE003874_7 (AE003874)
anthranilate synthase component I [Xylella fastidiosa]
Length = 487
Score = 250 bits (633), Expect = 2e-65
Identities = 144/371 (38%), Positives = 211/371 (56%), Gaps = 29/371 (7%)
Query: 86 GFLGGFMGYIAYDAVHNYIEGSIEEPS----------VFGYYPWVFIYNHGKGELRFYYL 135
GF GG +G+ ++ + YIE E + + +++ KG L
Sbjct: 111 GFTGGLVGWFGFECIQ-YIEPRFMEGKKRDELGTPDILLMLSEELAVFDSLKGRLYLIVH 169
Query: 136 RDPSFDPETIVERAKREEL---KFENGGA-------------EIIRTDANREEFMEMVEK 179
DP+ P +R ++ + GG E + RE++ +V +
Sbjct: 170 ADPA-QPHAYARAVERLDVLIYRLRQGGVDYPHSHISEVINEEDFHSSLTREQYHAVVRQ 228
Query: 180 GKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPET 238
+EY+ +GD+FQVV S+ + P+++YR L ++NPSPY + ++ +VG+SPE
Sbjct: 229 AQEYVRSGDIFQVVPSQRLCTQFHARPIDVYRALRTLNPSPYMYFIDIGATQVVGSSPEI 288
Query: 239 MGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSK 298
+ ++G V + PIAGT PRG TPE D+ + LL+D KERAEHVML+DL RND+ +V +
Sbjct: 289 LARLQGDVVTVRPIAGTRPRGATPEHDKRLEMELLADPKERAEHVMLIDLGRNDIGRVVE 348
Query: 299 PGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEII 358
GSV++ F + +YSHV HI SEV G L + D + A+FPAGT++GAPKIRA+EII
Sbjct: 349 AGSVQVKESFVIERYSHVMHIVSEVTGILKPGLNYVDVLRATFPAGTVSGAPKIRALEII 408
Query: 359 DELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYE 418
ELE R VY GA+GY G AD AIAIR A I+ +V+AG G+V DS P+ E+ E
Sbjct: 409 RELEPVCRNVYSGAVGYIGWHGDADTAIAIRTAVIQNGCLYVQAGGGVVYDSDPDLEWQE 468
Query: 419 TENKMKAVLKA 429
T NK +A+ +A
Sbjct: 469 TMNKARALFRA 479
>pir||T35072 probable anthranilate synthase component I - Streptomyces
coelicolor >gi|5596788|emb|CAB51435.1| (AL096884)
putative anthranilate synthase component I [Streptomyces
coelicolor A3(2)]
Length = 502
Score = 250 bits (631), Expect = 3e-65
Identities = 132/259 (50%), Positives = 172/259 (65%), Gaps = 1/259 (0%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
+F + VE KE I AG+ FQVV S+ + +++YR L + NPSPY ++L
Sbjct: 235 DFQDAVEDIKERIRAGEAFQVVPSQRFETPCTASALDVYRVLRATNPSPYMYLLRLDGFD 294
Query: 231 LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLAR 290
+VG+SPE + VE ++PIAGT PRG TP ED+ + LL+D KERAEH+MLVDL R
Sbjct: 295 VVGSSPEALVKVEDGRAMVHPIAGTRPRGATPREDQSLADELLADPKERAEHLMLVDLGR 354
Query: 291 NDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAP 350
ND+ +V +PGSV++V F V +YSHV HI S V G +A + FD + A FPAGTL+GAP
Sbjct: 355 NDLGRVCEPGSVEVVDFMSVERYSHVMHIVSTVTGRVAPGRTAFDVLTACFPAGTLSGAP 414
Query: 351 KIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADS 410
K RA++IIDELE SRR +YGG +GY G +D AIAIR A + A+V+AGAG+VADS
Sbjct: 415 KPRALQIIDELEPSRRGLYGGCVGYLDFAGDSDTAIAIRTALLRDGTAYVQAGAGVVADS 474
Query: 411 IPEKEFYETENKMKAVLKA 429
P E E NK AVL+A
Sbjct: 475 DPVAEDTECRNKAAAVLRA 493
>pir||A39128 anthranilate synthase (EC 4.1.3.27) component I [validated] -
Pseudomonas syringae pv. savastanoi
Length = 505
Score = 249 bits (629), Expect = 5e-65
Identities = 161/453 (35%), Positives = 237/453 (51%), Gaps = 37/453 (8%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGK-------GTFLDGKK 63
P+ +Y + + N ++ + K + + I + + G G ++
Sbjct: 30 PLSIYLKLADQPNSYLLESVQGGEKWGRYSIIGLPCRTVMRVHGHHVSVTHDGVEIESLD 89
Query: 64 VSNETNPFLSLKS-FNMDSASG-SGFLGGFMGYIAYDAVHNYIE---GSIEEPSVFGY-- 116
V + + + K+ +N+ + +G F GG +GY YD V Y+E + P G
Sbjct: 90 VEDPLDFVETFKARYNVPTIAGLPRFNGGLVGYFGYDCVR-YVEKRLANCPNPDPLGVPD 148
Query: 117 -----YPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFE-------------- 157
V ++++ G++ L DP+ A+ +EL +
Sbjct: 149 ILLMVSDAVVVFDNLAGKMHAIVLVDPAQQDAYARGVAQLDELMHKLRQPITPRRGLDLD 208
Query: 158 --NGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLIS 215
+ R+ + ++ V+ K+YI AGDV QVV S+ + P++LYR L
Sbjct: 209 RAPAADPVFRSSFTQGDYEAAVDTIKQYILAGDVMQVVPSQRMSIDFKAAPIDLYRALRC 268
Query: 216 INPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLS 274
NP+PY + F +VG+SPE + VE + + PIAGT PRG T E D + LLS
Sbjct: 269 FNPTPYMYFFNFGDFHVVGSSPEVLVRVEDNLITVRPIAGTRPRGATEEADLALEEDLLS 328
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
D KE AEH+ML+DL RNDV +VS+ G+VKL + +YS+V HI S V G+L +
Sbjct: 329 DHKEIAEHLMLIDLGRNDVGRVSEIGTVKLTEKMVIERYSNVMHIVSNVTGQLKNGLTAM 388
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
DA+ A PAGTL+GAPKIRAMEIIDELE +R VYGGA+GY + G D AIAIR A I+
Sbjct: 389 DALRAILPAGTLSGAPKIRAMEIIDELEPVKRGVYGGAVGYMAWNGNMDTAIAIRTAVIK 448
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
+ HV+AG GIVADS+P E+ ET NK +A++
Sbjct: 449 NGELHVQAGGGIVADSVPVLEWEETLNKRRAMV 481
>sp|Q9S358|TRPE_NEIMC ANTHRANILATE SYNTHASE COMPONENT I >gi|5051460|emb|CAB44980.1|
(AJ242842) putative anthranilate synthase component I
[Neisseria meningitidis]
Length = 491
Score = 249 bits (628), Expect = 6e-65
Identities = 162/456 (35%), Positives = 242/456 (52%), Gaps = 32/456 (7%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGK--GTFLDGKKVS-NE 67
P+ LY + ++ + + + ++I ++ SGK + +G+ V ++
Sbjct: 31 PLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHD 90
Query: 68 TNPFLSLKSFNM-----DSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW--- 119
NP +++F+ + S F GG +GY Y+ ++N+ + + P
Sbjct: 91 GNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTP 150
Query: 120 ---------VFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEII------ 164
+ + ++ G++ DPS R + E+++ + + I
Sbjct: 151 DILLMLSQELAVVDNLSGKIYLIVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGS 210
Query: 165 -RTDA----NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPS 219
T+A E F V K K+YIFAGD QVV S+ + + LYR L ++NPS
Sbjct: 211 KHTEAVSEFGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSSLALYRALRTLNPS 270
Query: 220 PYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKE 278
PY F +F +VG+SPE + E V + PIAGT RGKTP ED + LLSD KE
Sbjct: 271 PYLFYYDFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKE 330
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
AEHVML+DL RNDV ++SK G VK+ + KYSHV HI S V G L D D +
Sbjct: 331 IAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILA 390
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
A+FPAGTL+GAPK+RAMEII+E+E S+R +YGGA+G + D AIAIR A ++
Sbjct: 391 ATFPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTL 450
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
+V++GAG+VADS P E+ ET+NK +AV+ A ++Q
Sbjct: 451 YVQSGAGVVADSDPASEWQETQNKARAVIHAAQMVQ 486
>sp|P21689|TRPE_PSESS ANTHRANILATE SYNTHASE COMPONENT I >gi|151623|gb|AAA26016.1|
(M55911) anthranilate synthase large subunit
[Pseudomonas syringae]
Length = 505
Score = 249 bits (628), Expect = 6e-65
Identities = 162/453 (35%), Positives = 239/453 (51%), Gaps = 37/453 (8%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGK-------GTFLDGKK 63
P+ +Y + + N ++ + K + + I + + G G ++
Sbjct: 30 PLSIYLKLADQPNSYLLESVQGGEKWGRYSIIGLPCRTVMRVHGHHVSVTHDGVEIESLD 89
Query: 64 VSNETNPFLSLKS-FNMDSASG-SGFLGGFMGYIAYDAVHNYIE---GSIEEPSVFG--- 115
V + + + K+ +N+ + +G F GG +GY YD V Y+E + P G
Sbjct: 90 VEDPLDFVETFKARYNVPTIAGLPRFNGGLVGYFGYDCV-RYVEKRLANCPNPDPLGVPD 148
Query: 116 ----YYPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFE-------NGGAE-- 162
V ++++ G++ L DP+ A+ +EL + G +
Sbjct: 149 ILLMVSDAVVVFDNLAGKMHAIVLVDPAQQDAYARGVAQLDELMHKLRQPITPRRGLDLD 208
Query: 163 -------IIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLIS 215
+ R+ + ++ V+ K+YI AGDV QVV S+ + P++LYR L
Sbjct: 209 RAPRADPVFRSSFTQGDYEAAVDTIKQYILAGDVMQVVPSQRMSIDFKAAPIDLYRALRC 268
Query: 216 INPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLS 274
NP+PY + F +VG+SPE + VE + + PIAGT PRG T E D + LLS
Sbjct: 269 FNPTPYMYFFNFGDFHVVGSSPEVLVRVEDNLITVRPIAGTRPRGATEEADLALEEDLLS 328
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
D KE AEH+ML+DL RNDV +VS+ G+VKL + +YS+V HI S V G+L +
Sbjct: 329 DHKEIAEHLMLIDLGRNDVGRVSEIGTVKLTEKMVIERYSNVMHIVSNVTGQLKNGLTAM 388
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
DA+ A PAGTL+GAPKIRAMEIIDELE +R VYGGA+GY + G D AIAIR A I+
Sbjct: 389 DALRAILPAGTLSGAPKIRAMEIIDELEPVKRGVYGGAVGYMAWNGNMDTAIAIRTAVIK 448
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
+ HV+AG GIVADS+P E+ ET NK +A++
Sbjct: 449 NGELHVQAGGGIVADSVPVLEWEETLNKRRAMV 481
>sp|P96556|TRPE_ARTGO ANTHRANILATE SYNTHASE COMPONENT I >gi|1881742|gb|AAB49479.1|
(U89690) anthranilate synthase component I [Arthrobacter
globiformis]
Length = 531
Score = 249 bits (628), Expect = 6e-65
Identities = 125/267 (46%), Positives = 177/267 (65%), Gaps = 6/267 (2%)
Query: 169 NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFK 228
N E++ +++GKE I G+VFQVV+SR + + P+++YR L + NPSPY +I +
Sbjct: 233 NEPEYLAALDRGKEAIVDGEVFQVVISRRFEMECGASPLDVYRVLRNTNPSPYMYIFSLE 292
Query: 229 KI------LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEH 282
+VG+SPE + +V G V +PIAG+ PRGKT + D+ + LL+D+KERAEH
Sbjct: 293 DAAGRQYSIVGSSPEALVTVTGEDVITHPIAGSRPRGKTVDADKALAEELLADQKERAEH 352
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDL+RND+ KV GSV + +F +V ++SH+ H+ S V+G LA +D ++A+FP
Sbjct: 353 LMLVDLSRNDLSKVCVAGSVDVTQFMEVERFSHIMHLVSTVVGRLAPTAKAYDVLKATFP 412
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
AGTL+GAPK RA+ ++DELE RR +YGG +GY G D AIAIR A + +A+V+A
Sbjct: 413 AGTLSGAPKPRALRLLDELEPHRRGIYGGVVGYLDFAGDMDMAIAIRSALLREGRAYVQA 472
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
G GIVADS E ET NK A L+A
Sbjct: 473 GGGIVADSSNPAEAQETVNKAAAPLRA 499
>sp|Q9X7C5|TRPE_MYCLE ANTHRANILATE SYNTHASE COMPONENT I >gi|11268485|pir||T45254 probable
anthranilate synthase (EC 4.1.3.27) component I
[imported] - Mycobacterium leprae
>gi|4883460|emb|CAB43177.1| (AL049913) putative
anthranilate synthase component I [Mycobacterium leprae]
Length = 529
Score = 248 bits (627), Expect = 8e-65
Identities = 129/277 (46%), Positives = 182/277 (65%), Gaps = 7/277 (2%)
Query: 165 RTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFI 224
R EE+ +V+ + I AG+ FQVV S+ + + +DVDP+++YR L NPSPY ++
Sbjct: 225 RAQCTIEEYGAIVDHLVDQIAAGEAFQVVPSQRFEVDTDVDPIDVYRMLRVTNPSPYMYL 284
Query: 225 LEFKKI-------LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEK 277
L +VG+SPE + +V+ V +PIAGT RG+T EED+ + + LL+DEK
Sbjct: 285 LHVPNSDGATGFSIVGSSPEALVTVKDGRVTTHPIAGTRWRGQTEEEDQLLEKELLADEK 344
Query: 278 ERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAI 337
ERAEH+MLVDL RND+ +V PG+V++ + V +YSHV H+ S V G L + + DA+
Sbjct: 345 ERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHVERYSHVMHMVSTVTGLLGEGRTALDAV 404
Query: 338 EASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRK 397
A FPAGTL+GAPK+R+ME+I+E+EK+RR +YGG +GY G ADFAIAIR A +
Sbjct: 405 TACFPAGTLSGAPKVRSMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRDGI 464
Query: 398 AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
A+V+AG G+VADS E+ E NK +AVL A +
Sbjct: 465 AYVQAGGGVVADSNGPYEYIEASNKARAVLNAIAAAE 501
>sp|Q9WW00|TRPE_NEIGO ANTHRANILATE SYNTHASE COMPONENT I >gi|5051430|emb|CAB45014.1|
(AJ242839) putative anthranilate synthase component I
[Neisseria gonorrhoeae] >gi|5051441|emb|CAB44949.1|
(AJ242840) putative anthranilate synthase component I
[Neisseria gonorrhoeae]
Length = 491
Score = 248 bits (626), Expect = 1e-64
Identities = 159/456 (34%), Positives = 241/456 (51%), Gaps = 32/456 (7%)
Query: 11 PIKLYSVIREFENPFIFTIIGKDSKEAKLTYISASPEFTVEISGK--GTFLDGKKVSN-E 67
P+ LY + ++ + + + ++I ++ GK + +G+ V +
Sbjct: 31 PLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKAGGKHVDVYQNGEIVEQYD 90
Query: 68 TNPFLSLKSFNM-----DSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFGYYPW--- 119
NP +++F+ + S F GG +GY Y+ V+N+ + + P
Sbjct: 91 GNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETVYNFEHFAHRLKNTAKANPLGTP 150
Query: 120 ---------VFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIR----- 165
+ + ++ G++ DPS R + E+++ + + I
Sbjct: 151 DILLMLSQELAVIDNLSGKIHLIVYADPSQPDSYERARERLEDIRTQLRQSCAIPLSLGS 210
Query: 166 ------TDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPS 219
++ E F V+K K+YIFAGD QVV S+ + +P+ LYR L ++NPS
Sbjct: 211 KQTQAVSEFGEEPFKACVDKIKDYIFAGDCMQVVPSQRMSMEFTDNPLALYRALRTLNPS 270
Query: 220 PYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKE 278
PY F +F +VG+SPE + E V + PIAGT RGKTP ED + LLSD KE
Sbjct: 271 PYLFYYDFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKE 330
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
AEHVML+DL RNDV ++SK G VK+ + KYSHV HI S V G L + D +
Sbjct: 331 IAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGCLKEGVTNMDILA 390
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
A+FPAGTL+GAPK+RAMEII+E+E +R +YGGA+G + D AIAIR A I+
Sbjct: 391 ATFPAGTLSGAPKVRAMEIIEEIEPEKRGIYGGAVGVWGFNNDMDLAIAIRTAVIKNNTL 450
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
+++GAG+VADS P E+ ET+NK +AV++A ++Q
Sbjct: 451 FIQSGAGVVADSDPTSEWQETQNKARAVVRAAQMVQ 486
>dbj|BAA82094.1| (AB022602) anthranilate synthase alpha 1 subunit [Oryza sativa]
Length = 577
Score = 247 bits (623), Expect = 2e-64
Identities = 156/404 (38%), Positives = 220/404 (53%), Gaps = 59/404 (14%)
Query: 87 FLGGFMGYIAYDAVHNYIE---------------------GSIEEPSVFGYYP------- 118
F GG++G+ +YD V Y+E G + VF +
Sbjct: 171 FCGGWVGFFSYDTVR-YVETKKLPFSNAPEDDRNLPDIHLGLYNDIVVFDHVEKKTHVIH 229
Query: 119 WVFI---------YNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDAN 169
WV + Y GK +L R S + T+ A +L G+ + ++ +
Sbjct: 230 WVRVDCHESVDEAYEDGKNQLEALLSRLHSVNVPTLT--AGSVKLNVGQFGSALQKSSMS 287
Query: 170 REEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK 229
RE++ + V + KE+I AGD+FQVVLS+ + R+ DP E+YR L +NPSPY L+ +
Sbjct: 288 REDYKKAVVQAKEHILAGDIFQVVLSQRFERRTFADPFEVYRALRIVNPSPYMAYLQARG 347
Query: 230 -ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDL 288
ILV +SPE + VE RT+ P+AGT RGK+ ED+ + + LLSD K+ AEH+MLVDL
Sbjct: 348 CILVASSPEILTRVEKRTIVNRPLAGTIRRGKSKAEDKVLEQLLLSDGKQCAEHIMLVDL 407
Query: 289 ARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTG 348
RNDV KVSKPGSVK+ + +V +YSHV HI S V GEL DD +DA+ A+ P GT++G
Sbjct: 408 GRNDVGKVSKPGSVKVEKLMNVERYSHVMHISSTVTGELRDDLTCWDALRAALPVGTVSG 467
Query: 349 APKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIR---------------MAEI 393
APK+RAME+ID++E R Y G G S G D A+A+R +
Sbjct: 468 APKVRAMELIDQMEGKMRGPYSGGFGGVSFRGDMDIALALRTIVFPTGSRFDTMYSYTDK 527
Query: 394 EGRK---AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
R+ AH++AGAGIVADS P+ E E NK + +A + +
Sbjct: 528 NARQEWVAHLQAGAGIVADSKPDDEHQECLNKAAGLARAIDLAE 571
>sp|O06127|TRPE_MYCTU ANTHRANILATE SYNTHASE COMPONENT I >gi|7436745|pir||G70556 probable
trpE protein - Mycobacterium tuberculosis (strain H37RV)
>gi|3261772|emb|CAB08903.1| (Z95554) trpE [Mycobacterium
tuberculosis]
Length = 516
Score = 247 bits (623), Expect = 2e-64
Identities = 127/277 (45%), Positives = 181/277 (64%), Gaps = 7/277 (2%)
Query: 165 RTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFI 224
R EE+ +VE + I AG+ FQVV S+ + + +DVDP+++YR L NPSPY ++
Sbjct: 228 RAQRTVEEYGAIVEYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYL 287
Query: 225 LEFKKI-------LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEK 277
L+ +VG+SPE + +V +PIAGT RG+T +ED + + LL+D+K
Sbjct: 288 LQVPNSDGAVDFSIVGSSPEALVTVHEGWATTHPIAGTRWRGRTDDEDVLLEKELLADDK 347
Query: 278 ERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAI 337
ERAEH+MLVDL RND+ +V PG+V++ + + +YSHV H+ S V G+L + + DA+
Sbjct: 348 ERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEGRTALDAV 407
Query: 338 EASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRK 397
A FPAGTL+GAPK+RAME+I+E+EK+RR +YGG +GY G ADFAIAIR A +
Sbjct: 408 TACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGT 467
Query: 398 AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
A+V+AG G+VADS E+ E NK +AVL A +
Sbjct: 468 AYVQAGGGVVADSNGSYEYNEARNKARAVLNAIAAAE 504
>dbj|BAA02200.1| (D12706) anthranilate synthetase [Pseudomonas aeruginosa]
Length = 286
Score = 244 bits (617), Expect = 1e-63
Identities = 133/282 (47%), Positives = 175/282 (61%), Gaps = 1/282 (0%)
Query: 154 LKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKL 213
L+ G R RE++ V + K+YI AGD QVV S+ + P++LYR L
Sbjct: 1 LEAAQGREPAFRASFTREDYENAVGRIKDYILAGDCMQVVPSQRMSIEFKAAPIDLYRAL 60
Query: 214 ISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRL 272
NP+PY + F +VG+SPE + VE V + PIAGT PRG E D + + L
Sbjct: 61 RCFNPTPYMYFFNFGDFHVVGSSPEVLVRVEDGLVTVRPIAGTRPRGINEEADLALEQDL 120
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
LSD KE AEH+ML+DL RNDV +VS G+VK+ + +YS+V HI S V G+L +
Sbjct: 121 LSDAKEIAEHLMLIDLGRNDVGRVSDIGAVKVTEKMVIERYSNVMHIVSNVTGQLREGLS 180
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
DA+ A PAGTL+GAPKIRAMEIIDELE +R VYGGA+GY + G D AIAIR A
Sbjct: 181 AMDALRAILPAGTLSGAPKIRAMEIIDELEPVKRGVYGGAVGYLAWNGNMDTAIAIRTAV 240
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
I+ + HV+AG GIVADS+P E+ ET NK +A+ +A + +
Sbjct: 241 IKNGELHVQAGGGIVADSVPALEWEETINKRRAMFRAVALAE 282
>sp|P03963|TRPE_BACSU ANTHRANILATE SYNTHASE COMPONENT I >gi|1070509|pir||NNBS1
anthranilate synthase (EC 4.1.3.27) component I -
Bacillus subtilis >gi|143768|gb|AAA22865.1| (K01391)
TrpE protein [Bacillus subtilis]
>gi|143809|gb|AAA20862.1| (M80245) TrpE [Bacillus
subtilis] >gi|2634686|emb|CAB14184.1| (Z99115)
anthranilate synthase [Bacillus subtilis]
>gi|224469|prf||1106178E protein trpE [Bacillus
subtilis]
Length = 515
Score = 244 bits (616), Expect = 2e-63
Identities = 159/473 (33%), Positives = 249/473 (52%), Gaps = 51/473 (10%)
Query: 9 VEPIKLYSVIREFENPFIFTIIGKD--SKEAKLTYISASPEFTV-EISGKGTFLDG---- 61
V+ + +I + + + + KD S ++ ++I +P T+ E G+ + D
Sbjct: 28 VDTLTPIQMIEKLDREITYLLESKDDTSTWSRYSFIGLNPFLTIKEEQGRFSAADQDSKS 87
Query: 62 -------KKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYD-------AVHNYIEGS 107
K+V N N +K+ + G F+GG +GY++YD +V ++ + +
Sbjct: 88 LYTGNELKEVLNWMNTTYKIKTPEL----GIPFVGGAVGYLSYDMIPLIEPSVPSHTKET 143
Query: 108 IEEPSVFGYYPWVFIYNHGKGELRFYYL--------RDPSFDP------------ETIVE 147
E + + Y+H + F ++ D E +++
Sbjct: 144 DMEKCMLFVCRTLIAYDHETKNVHFIQYARLTGEETKNEKMDVFHQNHLELQNLIEKMMD 203
Query: 148 RAKREEL-----KFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRS 202
+ +EL ++ E + ++ + FM VEK K YI AGD+FQ VLS+++ +
Sbjct: 204 QKNIKELFLSADSYKTPSFETVSSNYEKSAFMADVEKIKSYIKAGDIFQGVLSQKFEVPI 263
Query: 203 DVDPVELYRKLISINPSPYTFILEF-KKILVGASPETMGSVEGRTVRINPIAGTAPRGKT 261
D ELYR L +NPSPY + ++ + +VG+SPE + V+ + I+PIAGT RG
Sbjct: 264 KADAFELYRVLRIVNPSPYMYYMKLLDREIVGSSPERLIHVQDGHLEIHPIAGTRKRGAD 323
Query: 262 PEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIES 321
EDE ++ L+ DEKE+AEH MLVDLARND+ +V++ GSV + F ++ +SHV HI S
Sbjct: 324 KAEDERLKVELMKDEKEKAEHYMLVDLARNDIGRVAEYGSVSVPEFTKIVSFSHVMHIIS 383
Query: 322 EVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGY 381
V G L DA+ ++FPAGTLTGAPKIRAM+++ ELE + R YGG I Y G
Sbjct: 384 VVTGRLKKGVHPVDALMSAFPAGTLTGAPKIRAMQLLQELEPTPRETYGGCIAYIGFDGN 443
Query: 382 ADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
D I IR ++ A ++AGAGIVADS+PE E+ E+ NK A+LK + +
Sbjct: 444 IDSCITIRTMSVKNGVASIQAGAGIVADSVPEAEYEESCNKAGALLKTIHIAE 496
>gb|AAF76162.1|AF266751_1 (AF266751) anthranilate synthase large subunit [Bordetella
bronchiseptica]
Length = 506
Score = 243 bits (613), Expect = 4e-63
Identities = 157/382 (41%), Positives = 207/382 (54%), Gaps = 35/382 (9%)
Query: 87 FLGGFMGYIAYDAVHNYIE--GSIEEPSVFG-----------YYPWVFIYNHGKGELRFY 133
F GG GY YD V + + G +P G + + I ++ G
Sbjct: 119 FCGGLAGYFGYDTVRHIEQRLGPAVKPFPDGMEEGTPDIMLLHVDELVIVDNLAGRTYLM 178
Query: 134 YLRDPSFDPETIVERAKR-----------EELKFENGGAEII-RTDANREEFMEMVEKGK 181
DP+ PE +R E+ + + + R D + +++ V + K
Sbjct: 179 VYADPA-QPEAYSRAQQRLLELRARLRRPVEIPYSHASMQTEERRDFQKADYLAAVARAK 237
Query: 182 EYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPETMG 240
EYI AGDV QV + + P+ LYR L S+NPSPY + F +VGASPE +
Sbjct: 238 EYIAAGDVMQVQVGQVIAKPFRDAPLSLYRALRSLNPSPYMYFWNFGDFQVVGASPEILV 297
Query: 241 SVE-----GRT---VRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARND 292
E G T + I P+AGT RG TPEED + L +D KERAEHVML+DLARND
Sbjct: 298 RQEQIDDQGETRSQITIRPLAGTRKRGGTPEEDLALAAELQADPKERAEHVMLIDLARND 357
Query: 293 VRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKI 352
V +V++ GSV++ + +YSHV H+ S V G+L D + A+FPAGTLTGAPK+
Sbjct: 358 VGRVAEIGSVRVSDTMVIERYSHVMHLVSNVAGKLLPGMSSMDVLRAAFPAGTLTGAPKV 417
Query: 353 RAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIP 412
RAMEIIDELE RR +YGGA GY S G D AIAIR I+ +V+A AGIVADS P
Sbjct: 418 RAMEIIDELEPVRRGIYGGAAGYLSYGGEMDVAIAIRTGVIKNGTLYVQAAAGIVADSSP 477
Query: 413 EKEFYETENKMKAVLKAFGVIQ 434
E E+ ETE K +AVL+A +Q
Sbjct: 478 EAEWAETEAKARAVLRAAEQVQ 499
>sp|P20170|TRPE_SYNY3 PROBABLE ANTHRANILATE SYNTHASE COMPONENT I >gi|7436737|pir||S74537
anthranilate synthase (EC 4.1.3.27) component I -
Synechocystis sp. (strain PCC 6803)
>gi|1651761|dbj|BAA16689.1| (D90899) anthranilate
synthetase alpha-subunit [Synechocystis sp.]
Length = 508
Score = 243 bits (613), Expect = 4e-63
Identities = 135/275 (49%), Positives = 178/275 (64%), Gaps = 11/275 (4%)
Query: 166 TDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFIL 225
++ +E+F+E V K+YI AGD+FQVVLS+ DP +LYR L INPSPY
Sbjct: 229 SNTEQEKFLEEVAIAKDYITAGDIFQVVLSQRLSTIYRDDPFKLYRSLRLINPSPYMAYY 288
Query: 226 EFKKI-LVGASPETM----GSVEGRTVR-INPIAGTAPRGKTPEEDEEIRRRLLSDEKER 279
F ++G+SPE M ++G+ + + PIAGT PRGKT EDE++ LL+D KE
Sbjct: 289 NFGHWQIIGSSPEVMVKADRQLDGKLMATVRPIAGTRPRGKTHPEDEQLAEELLNDPKEI 348
Query: 280 AEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEA 339
AEHVMLVDL RND+ +V GSVK+ + +YSHV HI S V+GELA DK +D ++A
Sbjct: 349 AEHVMLVDLGRNDLGRVCVQGSVKVNELMVIERYSHVMHIVSNVVGELASDKTAWDLLKA 408
Query: 340 SFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE----- 394
FPAGT++GAPKIRAMEII+ELE RR Y G GY+ G + AIAIR ++
Sbjct: 409 CFPAGTVSGAPKIRAMEIINELEPERRGPYSGVYGYYDFEGQLNTAIAIRTMVVQEQPDG 468
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+ V+ GAGIVADS P+KE+ ET NK + +L+A
Sbjct: 469 AHRVSVQTGAGIVADSDPQKEYEETLNKARGLLEA 503
>sp|P28820|PABB_BACSU PARA-AMINOBENZOATE SYNTHASE COMPONENT I (ADC SYNTHASE)
>gi|98427|pir||A37854 para-aminobenzoate synthase (EC
4.1.3.-) chain A (pabB) - Bacillus subtilis
>gi|143407|gb|AAA22694.1| (M34053) para-aminobenzoic
acid synthase, component I (pab) [Bacillus subtilis]
>gi|467463|dbj|BAA05309.1| (D26185) subunit A of
para-aminobenzoate [Bacillus subtilis]
>gi|2632341|emb|CAB11850.1| (Z99104) para-aminobenzoate
synthase (subunit A) [Bacillus subtilis]
Length = 470
Score = 241 bits (608), Expect = 1e-62
Identities = 148/365 (40%), Positives = 206/365 (55%), Gaps = 25/365 (6%)
Query: 87 FLGGFMGYIAYDAVHNYIEG-------SIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDP 138
F GG +G+++YD YIE +E P + F + + +Y+H + L +
Sbjct: 98 FQGGAIGFLSYDYAR-YIENFKMLSLDDLETPDIYFLVFDDIAVYDHQEESLWLITHVNG 156
Query: 139 SFDPETIVERAKRE-------------ELKFENGGAEIIRTDANREEFMEMVEKGKEYIF 185
S V+ ++ E E+K E G+ + F + VEK K+YI
Sbjct: 157 SDQETADVKLSELEQMWLTELPAVTSREMKPETAGS--FAAPFTEDGFSQAVEKIKQYIA 214
Query: 186 AGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPETMGSVEG 244
+GDVFQV LS V P ++Y+ L +NPSPY LE ++ SPE + S +G
Sbjct: 215 SGDVFQVNLSIRQSQSLSVHPYQIYKTLREVNPSPYMAYLETPDFQIICGSPELLVSKKG 274
Query: 245 RTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKL 304
+ + PIAGT RGKT EEDE + L+ +EKERAEHVMLVDL RND+ +VS+ GSV++
Sbjct: 275 KLLETRPIAGTRSRGKTNEEDEALANELIHNEKERAEHVMLVDLERNDLGRVSRYGSVRV 334
Query: 305 VRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKS 364
F + KYSHV HI S V GEL D D D I A FP GT+TGAPK+R MEII+ELE +
Sbjct: 335 NEFMAIEKYSHVMHIVSNVQGELQDGYDAVDIIHAVFPGGTITGAPKVRTMEIIEELEPT 394
Query: 365 RRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMK 424
RR +Y G+IG+F F I IR G +A +++GAG+V DS+P+ E+ E+ K
Sbjct: 395 RRGLYTGSIGWFGYNHDLQFNIVIRTIYATGGQAFMQSGAGVVIDSVPKHEYKESFKKAF 454
Query: 425 AVLKA 429
A+ +A
Sbjct: 455 AMQRA 459
>dbj|BAA82095.1| (AB022603) anthranilate synthase alpha 2 subunit [Oryza sativa]
Length = 606
Score = 239 bits (603), Expect = 5e-62
Identities = 151/404 (37%), Positives = 223/404 (54%), Gaps = 59/404 (14%)
Query: 87 FLGGFMGYIAYDAVHNYIE-------GSIEE----PSV-FGYYPWVFIYNHGKGELRFYY 134
F GG++G+ +YD V Y+E G+ ++ P V G Y V ++++ E + Y
Sbjct: 199 FTGGWVGFFSYDTVR-YVEKKKLPFSGAPQDDRNLPDVHLGLYDDVLVFDNV--EKKVYV 255
Query: 135 LRDPSFDPETIVERAKRE-------------------------ELKFENGGAEIIRTDAN 169
+ + D E A ++ +L G + ++
Sbjct: 256 IHWVNLDRHATTEDAFQDGKSRLNLLLSKVHNSNVPKLSPGFVKLHTRQFGTPLNKSTMT 315
Query: 170 REEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK 229
+E+ V + KE+I AGD+FQ+VLS+ + R+ +P E+YR L +NPSPY ++ +
Sbjct: 316 SDEYKNAVMQAKEHIMAGDIFQIVLSQRFERRTYANPFEVYRALRIVNPSPYMAYVQARG 375
Query: 230 -ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDL 288
+LV +SPE + V + P+AGT RGKT +EDE ++LLSDEK+ AEH+MLVDL
Sbjct: 376 CVLVASSPEILTRVRKGKIINRPLAGTVRRGKTEKEDEMQEQQLLSDEKQCAEHIMLVDL 435
Query: 289 ARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTG 348
RNDV KVSKPGSVK+ + ++ +YSHV HI S V GEL D +DA+ A+ P GT++G
Sbjct: 436 GRNDVGKVSKPGSVKVEKLMNIERYSHVMHISSTVSGELDDHLQSWDALRAALPVGTVSG 495
Query: 349 APKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIR---------------MAEI 393
APK++AME+IDELE +RR Y G +G S G A+A+R +
Sbjct: 496 APKVKAMELIDELEVTRRGPYSGGLGGISFDGDMLIALALRTIVFSTAPSHNTMYSYKDT 555
Query: 394 EGRK---AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
E R+ AH++AGAGIVADS P+ E E ENK A+ +A + +
Sbjct: 556 ERRREWVAHLQAGAGIVADSSPDDEQRECENKAAALARAIDLAE 599
>sp|P32068|TRPE_ARATH ANTHRANILATE SYNTHASE COMPONENT I-1 PRECURSOR
>gi|166604|gb|AAA32738.1| (M92353) anthranilate synthase
alpha subunit [Arabidopsis thaliana]
>gi|9759098|dbj|BAB09667.1| (AB005237) anthranilate
synthase component I-1 precursor [Arabidopsis thaliana]
Length = 595
Score = 238 bits (602), Expect = 7e-62
Identities = 156/457 (34%), Positives = 235/457 (51%), Gaps = 64/457 (14%)
Query: 34 SKEAKLTYISASPEFTVEISGKGTFLDGKKVSNETNPFLSLKSFNMDSASGSGFLGGFMG 93
+KE K+ + + E E + +K+S + NP L D+ F GG++G
Sbjct: 141 AKENKVIVMDHNNETMTEEFVEDPMEIPRKISEKWNPDPQLVQDLPDA-----FCGGWVG 195
Query: 94 YIAYDAVHNYIE---------------------GSIEEPSVF----------------GY 116
+ +YD V Y+E G ++ VF G
Sbjct: 196 FFSYDTVR-YVEKRKLPFSKAPEDDRNLPDMHLGLYDDVVVFDHVEKKAYVIHWIRLDGS 254
Query: 117 YPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEM 176
P+ Y++G L + +P + A L+ G + ++ EE+ E
Sbjct: 255 LPYEKAYSNGMQHLENLVAKLHDIEPPKLA--AGNVNLQTRQFGPSLDNSNVTCEEYKEA 312
Query: 177 VEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGAS 235
V K KE+I AGD+FQ+VLS+ + R+ DP E+YR L +NPSPY L+ + ILV +S
Sbjct: 313 VVKAKEHILAGDIFQIVLSQRFERRTFADPFEVYRALRVVNPSPYMGYLQARGCILVASS 372
Query: 236 PETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRK 295
PE + V+ + P+AGT+ RGK ED+ + + LL +EK+ AEH+MLVDL RNDV K
Sbjct: 373 PEILTKVKQNKIVNRPLAGTSKRGKNEVEDKRLEKELLENEKQCAEHIMLVDLGRNDVGK 432
Query: 296 VSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAM 355
V+K GSVK+ + ++ +YSHV HI S V GEL D +D + A+ P GT++GAPK++AM
Sbjct: 433 VTKYGSVKVEKLMNIERYSHVMHISSTVTGELQDGLTCWDVLRAALPVGTVSGAPKVKAM 492
Query: 356 EIIDELEKSRRRVYGGAIGYFSITGYADFAIAIR---------------MAEIEGRK--- 397
E+IDELE +RR Y G G S TG D A+++R + R+
Sbjct: 493 ELIDELEPTRRGPYSGGFGGVSFTGDMDIALSLRTIVFPTACQYNTMYSYKDANKRREWV 552
Query: 398 AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
A+++AGAG+VADS P+ E E +NK + +A + +
Sbjct: 553 AYLQAGAGVVADSDPQDEHCECQNKAAGLARAIDLAE 589
>pir||JQ1684 anthranilate synthase (EC 4.1.3.27) alpha-1 chain - Arabidopsis
thaliana
Length = 595
Score = 238 bits (602), Expect = 7e-62
Identities = 156/457 (34%), Positives = 235/457 (51%), Gaps = 64/457 (14%)
Query: 34 SKEAKLTYISASPEFTVEISGKGTFLDGKKVSNETNPFLSLKSFNMDSASGSGFLGGFMG 93
+KE K+ + + E E + +K+S + NP L D+ F GG++G
Sbjct: 141 AKENKVIVMDHNNETMTEEFVEDPMEIPRKISEKWNPDPQLVQDLPDA-----FCGGWVG 195
Query: 94 YIAYDAVHNYIE---------------------GSIEEPSVF----------------GY 116
+ +YD V Y+E G ++ VF G
Sbjct: 196 FFSYDTVR-YVEKRKLPFSKAPEDDRNLPDMHLGLYDDVVVFDHVEKKAYVIHWIRLDGS 254
Query: 117 YPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEM 176
P+ Y++G L + +P + A L+ G + ++ EE+ E
Sbjct: 255 LPYEKAYSNGMQHLENLVAKLHDIEPPKLA--AGNVNLQTRQFGPSLDNSNVTCEEYKEA 312
Query: 177 VEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGAS 235
V K KE+I AGD+FQ+VLS+ + R+ DP E+YR L +NPSPY L+ + ILV +S
Sbjct: 313 VVKAKEHILAGDIFQIVLSQRFERRTFADPFEVYRALRVVNPSPYMGYLQARGCILVASS 372
Query: 236 PETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRK 295
PE + V+ + P+AGT+ RGK ED+ + + LL +EK+ AEH+MLVDL RNDV K
Sbjct: 373 PEILTKVKQNKIVNRPLAGTSKRGKNEVEDKRLEKELLENEKQCAEHIMLVDLGRNDVGK 432
Query: 296 VSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAM 355
V+K GSVK+ + ++ +YSHV HI S V GEL D +D + A+ P GT++GAPK++AM
Sbjct: 433 VTKYGSVKVEKLMNIERYSHVMHISSTVTGELQDGLTCWDVLRAALPVGTVSGAPKVKAM 492
Query: 356 EIIDELEKSRRRVYGGAIGYFSITGYADFAIAIR---------------MAEIEGRK--- 397
E+IDELE +RR Y G G S TG D A+++R + R+
Sbjct: 493 ELIDELEPTRRGPYSGGFGGVSFTGDMDIALSLRTIVFPTACQYNTMYSYKDANKRREWV 552
Query: 398 AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
A+++AGAG+VADS P+ E E +NK + +A + +
Sbjct: 553 AYLQAGAGVVADSDPQDEHCECQNKAACLARAIDLAE 589
>pir||T50834 anthranilate synthase (EC 4.1.3.27) alpha chain [imported] - Ruta
graveolens >gi|960291|gb|AAA74901.1| (L34344)
anthranilate synthase alpha subunit [Ruta graveolens]
Length = 613
Score = 237 bits (599), Expect = 2e-61
Identities = 151/402 (37%), Positives = 221/402 (54%), Gaps = 55/402 (13%)
Query: 87 FLGGFMGYIAYDAVHNYIEGSIEEPSV------------FGYYPWVFIYNHGKGE---LR 131
F GG++G+ +YD V Y+E S G Y V +++H + + +
Sbjct: 204 FCGGWVGFFSYDTVR-YVEKKKLPFSKAPQDDRNLADMHLGLYNDVIVFDHVEKKVYVIH 262
Query: 132 FYYLRDPSFDP----------ETIVERAKRE----------ELKFENGGAEIIRTDANRE 171
+ L S + E +V R + E +L + G + +++ E
Sbjct: 263 WVRLNQQSSEEKAYAEGLEHLERLVSRVQDENTPRLAPGSIDLHTGHFGPPLKKSNMTCE 322
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-I 230
E+ V KE+I AGD+FQ+VLS+ + R+ DP E+YR L +NPSPY ++ + +
Sbjct: 323 EYKMAVLAAKEHIQAGDIFQIVLSQRFERRTFADPFEVYRALRVVNPSPYMTYMQARGCV 382
Query: 231 LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLAR 290
LV +SPE + V+ + P+AGTA RG+T EEDE + +LL D K+ AEHVMLVDL R
Sbjct: 383 LVASSPEILTRVKKNKIVNRPLAGTARRGRTTEEDEMLETQLLKDAKQCAEHVMLVDLGR 442
Query: 291 NDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAP 350
NDV KVSK GSVK+ + +V +YSHV HI S V GEL D+ +DA+ A+ P GT++GAP
Sbjct: 443 NDVGKVSKSGSVKVEKLMNVERYSHVMHISSTVTGELQDNLSCWDALRAALPVGTVSGAP 502
Query: 351 KIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE-GRK------------ 397
K++AME+IDELE +RR Y G G S TG D A+A+R + G +
Sbjct: 503 KVKAMELIDELEVNRRGPYSGGFGGISFTGDMDIALALRTIVFQTGTRYDTMYSYKNATK 562
Query: 398 -----AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
A+++AGAGIVADS P+ E E +NK + +A + +
Sbjct: 563 RRQWVAYLQAGAGIVADSDPDDEHRECQNKAAGLARAIDLAE 604
>dbj|BAB03809.1| (AP001507) para-aminobenzoate synthase component I [Bacillus
halodurans]
Length = 486
Score = 237 bits (599), Expect = 2e-61
Identities = 149/380 (39%), Positives = 212/380 (55%), Gaps = 23/380 (6%)
Query: 73 SLKSFNMDSASGSG-FLGGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYN 124
+L S+ ++ G+ F GG +G+ +YD V + + P + F + VFIY+
Sbjct: 95 ALASYQAETLPGAPPFQGGAIGFFSYDLVREIERLPTIAQDDLNLPDLYFLIFDDVFIYD 154
Query: 125 HGKGELRFYYLRDPSFDPETIVERAKREELKF-------ENGGAEIIRTDANR------E 171
H K ++ + ++ + + + ++ + E + E + T+ + E
Sbjct: 155 HEK-KVAWIFVHGDASEQDLSEQKLRHYEATWKQPVSLDEEVATSYLETEGEKVHSFSEE 213
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
F + VE+ +EYI AGDVFQV LS P+ +Y L INPSPY L
Sbjct: 214 TFAKAVERVREYIAAGDVFQVNLSVREGRPLRTTPLSIYEALRQINPSPYMSYLHTPDFQ 273
Query: 231 LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLAR 290
LV SPE + + R + PIAGT RG T +EDE + + LLS+EKERAEHVMLVDL R
Sbjct: 274 LVSGSPELLIKKDSRKLSTRPIAGTRSRGATADEDEALVQTLLSNEKERAEHVMLVDLER 333
Query: 291 NDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAP 350
ND+ +VS+ GSV++ V KYSHV HI S V G L + D FDAI A+FP GT+TGAP
Sbjct: 334 NDLGRVSEYGSVEVNELMVVEKYSHVMHIVSNVRGVLKEGLDAFDAIRATFPGGTITGAP 393
Query: 351 KIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADS 410
K+R MEII+ELE RR +Y G+IG+ G + I IR + A+V+AGAG+V DS
Sbjct: 394 KVRTMEIIEELEPVRRGIYTGSIGWIGYNGDMELNIVIRTMLCKDEMAYVQAGAGVVIDS 453
Query: 411 IPEKEFYETENKMKAVLKAF 430
P E+ E+ K KA+ +A+
Sbjct: 454 NPRYEYKESLKKAKALWRAY 473
>sp|P21690|TRPE_SPIAU ANTHRANILATE SYNTHASE COMPONENT I >gi|94597|pir||A39132
anthranilate synthase (EC 4.1.3.27) component I -
Spirochaeta aurantia >gi|152900|gb|AAA26591.1| (M55917)
anthranilate synthase component I [Spirochaeta aurantia]
Length = 482
Score = 233 bits (588), Expect = 3e-60
Identities = 127/274 (46%), Positives = 177/274 (64%), Gaps = 2/274 (0%)
Query: 161 AEIIRTDANREE-FMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPS 219
AE++ D + +E + V ++ + AG++ Q V SR ++++++ +E YR+L S NPS
Sbjct: 207 AEVLPQDYDPDETYKANVGAMRQEVIAGNLLQGVPSRRLLVKTEMPAIEAYRRLRSSNPS 266
Query: 220 PYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKE 278
PY F L+F L ASPE V+G T I PIAGT RG T ED + LL+D KE
Sbjct: 267 PYMFYLDFGDYQLFRASPELHVKVKGGTAEIRPIAGTRRRGATDAEDRALEAELLADVKE 326
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
RAEH+MLVDLARND+ ++ +PG+V++ + + +YSHV HI S V G L DDK DA+
Sbjct: 327 RAEHLMLVDLARNDLGRICQPGTVQVKDSYFIERYSHVMHIVSSVEGRLKDDKTGIDALR 386
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
ASFPAGT++GAPKIRA+E+ID LE +RR Y G +G+ S G D IAIR A +G
Sbjct: 387 ASFPAGTVSGAPKIRAIEVIDRLEPVQRRFYSGVVGHLSPDGSLDTCIAIRSALKKGDTM 446
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
++AG GIV DS P++E ET KM+A ++ G+
Sbjct: 447 VLQAGGGIVFDSNPDRELEETYEKMRATARSLGL 480
>pir||T40974 anthranilate synthase component i - fission yeast
(Schizosaccharomyces pombe) >gi|3790254|emb|CAA21443.1|
(AL031966) anthranilate synthase component i
[Schizosaccharomyces pombe]
Length = 489
Score = 219 bits (552), Expect = 5e-56
Identities = 138/380 (36%), Positives = 202/380 (52%), Gaps = 47/380 (12%)
Query: 87 FLGGFMGYIAYDAVHNYIEGSIEEPS------------------VFGY-YPWVFIYNH-- 125
F GG +GY++YD + Y E + E P F + Y V I +H
Sbjct: 104 FSGGAVGYVSYDCI-KYFEPTTEMPLEDTLGLPEAMFFMTDDLVAFDHAYQTVKIISHVC 162
Query: 126 -----------GKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFM 174
+ L+ PE + K+ L +E +++ + +
Sbjct: 163 IQQGRPIEEAYEAAVFKINMLKKKLESPEIPLPEQKKVHLGYE------AKSNVGEDGYK 216
Query: 175 EMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVG 233
V KE+IF GD+FQ V S+ R+D+ P LYR L ++NPSPY F + ++G
Sbjct: 217 AFVSNLKEHIFNGDIFQAVPSQRIARRTDLHPFNLYRHLRTVNPSPYMFYIHCDDFDIIG 276
Query: 234 ASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDV 293
ASPE + E + +PIAGT PRGKT EEDE + LL+ K+RAEHVMLVDLARNDV
Sbjct: 277 ASPELLVKSEHGRIINHPIAGTVPRGKTKEEDEAYAKDLLASVKDRAEHVMLVDLARNDV 336
Query: 294 RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIR 353
+V + + + + K+SHVQH+ S+V G L DK FDA + FPAGT++G+PK+R
Sbjct: 337 SRVCDLDTTSVDKLMTIEKFSHVQHLVSQVSGVLRPDKTRFDAFRSIFPAGTVSGSPKVR 396
Query: 354 AMEIIDELEKSRRRVYGGAIGYFSITGY----ADFAIAIRMAEIEGRKAHVRAGAGIVAD 409
A++++ LEK +R +Y GA+G + GY D IAIR + +++AG GIV D
Sbjct: 397 AIQLVYGLEKEKRGIYAGAVGRW---GYEDDNMDTCIAIRTMVYKDGTVYLQAGGGIVFD 453
Query: 410 SIPEKEFYETENKMKAVLKA 429
S + E+ ET NK+++ + A
Sbjct: 454 SDEQDEYVETLNKLRSNVTA 473
>sp|Q9Y8T0|TRPE_AERPE ANTHRANILATE SYNTHASE COMPONENT I
Length = 438
Score = 219 bits (552), Expect = 5e-56
Identities = 144/385 (37%), Positives = 204/385 (52%), Gaps = 24/385 (6%)
Query: 61 GKKVSNETNPFLSLKSFN---------MDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEP 111
G++ S+ET+ + + + S + FL + + + + + G E P
Sbjct: 61 GRRKSSETDAIRAYEELERLADDKCRALPCRSPTFFLVSYEAVVGEEPWLSRLVGRHEWP 120
Query: 112 SVFGYYP-WVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANR 170
+ + P +V +Y+H G + P P + E E +E +R
Sbjct: 121 GMTAFSPEYVVVYDHAGGRVSVCPGDTPLPAPASRKESFSAEGPTYET----------SR 170
Query: 171 EEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFK-K 229
+ F MV E I AG+ FQVVLSR R Y +L NPSPY + +
Sbjct: 171 KGFEAMVADALERIRAGEAFQVVLSRVERYRVWGSLFSAYERLADANPSPYLYYARLGGR 230
Query: 230 ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLA 289
+++G+SPE + +E V +PIAGT PRG TP ED E+ LL+DEKERAEHVMLVDLA
Sbjct: 231 VIIGSSPELLVKLEAGRVETHPIAGTRPRGSTPIEDIELEVELLNDEKERAEHVMLVDLA 290
Query: 290 RNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGA 349
RND+ +VS PG+V++ F D+ +Y V HI S V G +A++A PAGT++GA
Sbjct: 291 RNDITRVSIPGTVQVTSFMDIERYETVMHIVSRVEGVTRPSTTFVEALKALHPAGTVSGA 350
Query: 350 PKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEI--EGRKAHVRAGAGIV 407
PK RAMEII ELE+ R Y GAIG + + AI +R A + +G RAGAGIV
Sbjct: 351 PKPRAMEIIAELEEEARGPYAGAIGVAG-SSAGEAAIVLRSAWLLDDGETLEARAGAGIV 409
Query: 408 ADSIPEKEFYETENKMKAVLKAFGV 432
DS PE+E+ ET K+ ++ +A GV
Sbjct: 410 YDSKPEREYMETVQKLGSLKRALGV 434
>pir||T49199 anthranilate synthase alpha-1 chain-like protein - Arabidopsis
thaliana >gi|7573482|emb|CAB87841.1| (AL163832)
anthranilate synthase alpha-1 chain-like protein
[Arabidopsis thaliana]
Length = 526
Score = 217 bits (547), Expect = 2e-55
Identities = 143/403 (35%), Positives = 211/403 (51%), Gaps = 62/403 (15%)
Query: 87 FLGGFMGYIAYDAVHNYIE--------GSIEEPSV----FGYYPWVFIYNHGKGELRFYY 134
F GG++GY +YD V Y E +++ ++ G Y V +++H + ++ +
Sbjct: 120 FCGGWVGYFSYDTVP-YAEKRKLPLSKAPVDDRNLPDMHLGLYDDVVVFDHVEKKIHIIH 178
Query: 135 L----RDPSFDP---------ETIVERAK----------REELKFENGGAEIIRTDANRE 171
+ SFD E +V R K +L G + ++ +
Sbjct: 179 WVRLSENSSFDDVYANAVKHLEELVSRIKCMNPPKLPYGSVDLHTNQFGTPLEKSSMTSD 238
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-I 230
+ V + KE+I AGD+FQ+VLS+ + + P E+YR L +NPSP L+ + I
Sbjct: 239 AYKNAVLQAKEHILAGDIFQIVLSQRFERHTFAHPFEVYRALRIVNPSPSMCYLQARGCI 298
Query: 231 LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLAR 290
LV +SPE + V+ + P+AGTA RGK+ EED+ + LL DEK+ AEH+MLVDL R
Sbjct: 299 LVASSPEILTRVKKNKIVNRPLAGTARRGKSFEEDQMLEEALLKDEKQCAEHIMLVDLGR 358
Query: 291 NDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAP 350
NDV KVSK GSVK+ R ++ +YSHV HI S VIGEL ++ +D + A+ P GT
Sbjct: 359 NDVGKVSKNGSVKVERLMNIERYSHVMHISSTVIGELQENLTCWDTLRAALPVGT----- 413
Query: 351 KIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRK------------- 397
++AME+IDELE +RR Y G G S TG D A+A+R +
Sbjct: 414 -VKAMELIDELEVTRRGPYSGGFGSVSFTGDMDIALALRTIVFPTQARYDTMYSYKDKDT 472
Query: 398 ------AHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
A+++AGAGIVADS PE E E +NK + +A + +
Sbjct: 473 PRREWIAYLQAGAGIVADSDPEDEHRECQNKAAGLARAIDLAE 515
>pir||B72489 probable anthranilate synthase component I APE2553 - Aeropyrum
pernix (strain K1) >gi|5106259|dbj|BAA81570.1|
(AP000064) 317aa long hypothetical anthranilate synthase
component I [Aeropyrum pernix]
Length = 317
Score = 216 bits (544), Expect = 4e-55
Identities = 127/279 (45%), Positives = 168/279 (59%), Gaps = 4/279 (1%)
Query: 157 ENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISI 216
E+ AE + +R+ F MV E I AG+ FQVVLSR R Y +L
Sbjct: 36 ESFSAEGPTYETSRKGFEAMVADALERIRAGEAFQVVLSRVERYRVWGSLFSAYERLADA 95
Query: 217 NPSPYTFILEFK-KILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSD 275
NPSPY + ++++G+SPE + +E V +PIAGT PRG TP ED E+ LL+D
Sbjct: 96 NPSPYLYYARLGGRVIIGSSPELLVKLEAGRVETHPIAGTRPRGSTPIEDIELEVELLND 155
Query: 276 EKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFD 335
EKERAEHVMLVDLARND+ +VS PG+V++ F D+ +Y V HI S V G +
Sbjct: 156 EKERAEHVMLVDLARNDITRVSIPGTVQVTSFMDIERYETVMHIVSRVEGVTRPSTTFVE 215
Query: 336 AIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEI-- 393
A++A PAGT++GAPK RAMEII ELE+ R Y GAIG + + AI +R A +
Sbjct: 216 ALKALHPAGTVSGAPKPRAMEIIAELEEEARGPYAGAIGVAG-SSAGEAAIVLRSAWLLD 274
Query: 394 EGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
+G RAGAGIV DS PE+E+ ET K+ ++ +A GV
Sbjct: 275 DGETLEARAGAGIVYDSKPEREYMETVQKLGSLKRALGV 313
>sp|P22099|TRPE_VIBPA ANTHRANILATE SYNTHASE COMPONENT I >gi|48486|emb|CAA35031.1|
(X17149) anthranilate synthase; alpha subunit [Vibrio
parahaemolyticus]
Length = 541
Score = 215 bits (541), Expect = 1e-54
Identities = 123/268 (45%), Positives = 166/268 (61%), Gaps = 10/268 (3%)
Query: 171 EEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI 230
++F ++V KE++ GD+FQVV SR + L P+ Y++L NPSPY F ++ +
Sbjct: 263 QDFCQIVRDLKEFVVKGDIFQVVPSRRFTLPCP-SPLAAYKELKQSNPSPYMFYMQDELF 321
Query: 231 -LVGASPETMGSVEGRT--VRINPIAGTAPRGKTP------EEDEEIRRRLLSDEKERAE 281
L GASPE+ E T + I PIAGT RGK P + D I L SD+KE AE
Sbjct: 322 TLFGASPESALKYETDTNQIEIYPIAGTRRRGKRPNGEIDFDLDGRIELELRSDKKENAE 381
Query: 282 HVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF 341
H+MLVDLARNDV ++S+ G+ + V +YSHV H+ S V+G+L DD D A +A
Sbjct: 382 HMMLVDLARNDVARISQAGTRHVADLLKVDRYSHVMHLVSRVVGQLRDDLDALHAYQACM 441
Query: 342 PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVR 401
GTLTGAPKIRAM++I ++E +RR YGGA+GY + G D I IR+A +E A V+
Sbjct: 442 NMGTLTGAPKIRAMQLIRDVEGARRGSYGGAVGYLTGEGTLDTCIVIRLAYVENGIAQVQ 501
Query: 402 AGAGIVADSIPEKEFYETENKMKAVLKA 429
AGAG+V DS P+ E ET K +AV+ A
Sbjct: 502 AGAGVVFDSDPQAEADETRGKAQAVISA 529
>gb|AAG28534.1|AF198621_5 (AF198621) p-aminobenzoate synthase [Bacillus stearothermophilus]
Length = 414
Score = 213 bits (538), Expect = 2e-54
Identities = 131/347 (37%), Positives = 198/347 (56%), Gaps = 23/347 (6%)
Query: 61 GKKVSNETNPFLSLKSF----NMDSASGS-GFLGGFMGYIAYDAVH------NYIEGSIE 109
G++ E NP L LK + ++ +A F GG +GYI+YD + +Y + ++
Sbjct: 68 GEEKRYEGNPLLLLKQWFAGVSLSAADDDIPFQGGVIGYISYDGMRYIEKIPSYAKDDLQ 127
Query: 110 EPSVFGY-YPWVFIYNHGKGELRF--YYLRDPSFDPETIVE-------RAKREELKFENG 159
P ++ + + VF+Y+H K +L +Y F+ E + + K+E++++
Sbjct: 128 LPYMYFFIFDDVFVYDHQKHQLHMIVHYRDGEEFEAERRLSFYEMCWLQEKKEDIRWAFQ 187
Query: 160 GAEIIRT-DANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINP 218
++ + +EEF++ V + ++YI G+VFQV LS V P +Y +L INP
Sbjct: 188 TKKVDPSVSMTKEEFVQAVCRVQQYIAQGEVFQVNLSVRQSKPLLVHPFHIYEQLRVINP 247
Query: 219 SPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEK 277
PY + F + +V S E + G + PIAGT RGKT EEDE I ++LL++EK
Sbjct: 248 FPYMAYIHFPEFQIVSGSRELLVKKRGNDISTRPIAGTRSRGKTKEEDERIAQKLLANEK 307
Query: 278 ERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAI 337
E AEH MLVDL RND+ +V + G+VK+ + + +YSHV HI S V G+L KD FD I
Sbjct: 308 EIAEHAMLVDLERNDLGRVCQYGTVKVDEWMTIERYSHVMHIVSHVSGKLQQGKDAFDVI 367
Query: 338 EASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADF 384
+A FP GT+TGAPK+R MEII+ELE RR +Y G+IG+ G +F
Sbjct: 368 QAMFPGGTITGAPKVRTMEIIEELEPVRRGLYTGSIGWIGFNGDMEF 414
>pir||B83427 para-aminobenzoate synthase component I PA1758 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9947736|gb|AAG05147.1|AE004601_12 (AE004601)
para-aminobenzoate synthase component I [Pseudomonas
aeruginosa]
Length = 453
Score = 212 bits (535), Expect = 5e-54
Identities = 129/358 (36%), Positives = 192/358 (53%), Gaps = 21/358 (5%)
Query: 87 FLGGFMGYIAYDA------VHNYIEGSIEEP-SVFGYYPWVFIYNHGKGELRFYYLRDPS 139
F GG +GY++YD + + + P + G Y W I +H G + + P
Sbjct: 89 FAGGLLGYLSYDLGRRIERIGEHARDDLGLPLASVGLYAWALISDHQAGTSQLVF--HPR 146
Query: 140 FDPETIVERAK-----REELKFENGGAEII---RTDANREEFMEMVEKGKEYIFAGDVFQ 191
D ER + EE + G +++ R + ++ + + + ++YI AGD +Q
Sbjct: 147 LDER---ERQRLIALFSEEAQGTAGNFKLLGKFRRSISASDYRQAIRRIQDYIQAGDCYQ 203
Query: 192 VVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRIN 250
V S+ + P YR L P+P++ L ++ SPE + V
Sbjct: 204 VNYSQRFQAACSGSPWPAYRALREACPTPFSGYLRLADGAILSLSPERFLKLGKGKVETR 263
Query: 251 PIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDV 310
PI GT PRGKTPEED + LL+ K+RAE++M+VDL RND+ + +PGSV++ F +
Sbjct: 264 PIKGTRPRGKTPEEDMALAASLLASPKDRAENLMIVDLLRNDIGRSCQPGSVRVPELFAL 323
Query: 311 IKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYG 370
Y +V H+ S V GELA KD D +E SFP G++TGAPKIRAM+IIDELE SRR +Y
Sbjct: 324 ESYPNVHHLVSSVTGELAPGKDALDLLEGSFPGGSITGAPKIRAMQIIDELEPSRRGIYC 383
Query: 371 GAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLK 428
G++ Y + G D +IAIR + + G GIVADS E E+ ET +K++ +L+
Sbjct: 384 GSLFYLDVRGEMDSSIAIRTLLVRDGQVSCWGGGGIVADSHWEDEYQETLDKVRVLLE 441
>pir||A82233 anthranilate synthase component I VC1174 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655650|gb|AAF94333.1| (AE004197) anthranilate
synthase component I [Vibrio cholerae]
Length = 523
Score = 212 bits (534), Expect = 7e-54
Identities = 123/275 (44%), Positives = 168/275 (60%), Gaps = 10/275 (3%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+ T+ + F ++V K+Y+ GDVFQVV SR + L P+ Y++L NPSPY F
Sbjct: 241 VTTNISDAAFCDIVRDLKQYVVKGDVFQVVPSRRFRLPCP-SPLAAYQRLKQSNPSPYMF 299
Query: 224 ILEFKKI-LVGASPETMGSVEGRT--VRINPIAGTAPRGKTPEE------DEEIRRRLLS 274
++ ++ L GASPE+ E T V I PIAGT RGK + D I L +
Sbjct: 300 YMQDERFTLFGASPESALKYEMHTNQVEIYPIAGTRRRGKRADGSIDFDLDSRIELELRT 359
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
D+KE AEH+MLVDLARNDV ++S+ G+ + V +YSHV H+ S V+G+L +D D
Sbjct: 360 DKKENAEHMMLVDLARNDVARISQAGTRHVADLLQVDRYSHVMHLVSRVVGQLREDLDAL 419
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A +A GTLTGAPKIRAM++I ++E++RR YGGA+GY + G D I IR A +E
Sbjct: 420 HAYQACMNMGTLTGAPKIRAMQLIRDVEQARRGSYGGAVGYLTGEGDLDTCIVIRSAYVE 479
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A V+AGAG+V DS P+ E ET K +AV+ A
Sbjct: 480 NGIAQVQAGAGVVYDSDPQAEADETRGKAQAVISA 514
>pir||T43181 probable anthranilate synthase (EC 4.1.3.27) chain I - fission
yeast (Schizosaccharomyces pombe) (fragment)
>gi|1749720|dbj|BAA13917.1| (D89256) similar to
Saccharomyces cerevisiae anthranilate synthase component
I, SWISS-PROT Accession Number P00899
[Schizosaccharomyces pombe]
Length = 364
Score = 211 bits (531), Expect = 1e-53
Identities = 119/293 (40%), Positives = 175/293 (59%), Gaps = 14/293 (4%)
Query: 142 PETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLR 201
PE + K+ L +E +++ + + V KE+IF GD+FQ V S+ R
Sbjct: 65 PEIPLPEQKKVHLGYE------AKSNVGEDGYKAFVSNLKEHIFNGDIFQAVPSQRIARR 118
Query: 202 SDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGK 260
+D+ P LYR L ++NPSP+ F + ++GASPE + E + +PIAGT PRGK
Sbjct: 119 TDLHPFNLYRHLRTVNPSPFMFYIHCDDFDIIGASPELLVKSEHGRIINHPIAGTVPRGK 178
Query: 261 TPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIE 320
T EEDE + LL+ ++RAEHVMLVDLARNDV +V + + + + K+SHVQH+
Sbjct: 179 TEEEDEAYAKDLLASVQDRAEHVMLVDLARNDVSRVCDLDTTSVDKLRTIEKFSHVQHLV 238
Query: 321 SEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITG 380
S+V G L DK FDA + FPAGT++G+PK+RA+++++ LEK R Y GA+G + G
Sbjct: 239 SQVSGVLRPDKTRFDAFRSIFPAGTVSGSPKVRAIQLVNGLEKEERGRYAGAVGRW---G 295
Query: 381 Y----ADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
Y D IAIR + +++AG GIV DS + E+ ET NK+++ + A
Sbjct: 296 YEDDNMDTCIAIRTMVYKDGTVYLQAGGGIVFDSDEQDEYVETLNKLRSNVTA 348
>sp|Q9ZER9|TRPE_BUCPS ANTHRANILATE SYNTHASE COMPONENT I >gi|4160156|emb|CAA09996.1|
(AJ012334) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 520
Score = 210 bits (530), Expect = 2e-53
Identities = 117/275 (42%), Positives = 175/275 (63%), Gaps = 10/275 (3%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
++ + +E++++++K K+ I GD+FQVV SR++ L + + Y++L NPSPY F
Sbjct: 236 LKCNLTDKEYIKIIKKMKQSIKKGDIFQVVPSRKFYLPC-ISSLSAYQRLKQSNPSPYMF 294
Query: 224 ILEFKKI-LVGASPETMGSVEGRT--VRINPIAGTAPRGKTP------EEDEEIRRRLLS 274
++ L GASPE+ + ++ + I PIAGT PRGKT + D +I +
Sbjct: 295 FMQDSDFTLFGASPESSLKYDSKSKKIEIYPIAGTRPRGKTENGLIDLDLDSKIELEMRM 354
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
+EKE +EH+MLVDLARND+ ++ +PGS + V +YS V H+ S+++G L + D+F
Sbjct: 355 NEKELSEHLMLVDLARNDLARICEPGSRYVASLTKVDRYSCVMHLVSKIVGRLKSNLDIF 414
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A A GTLTGAPKI+AME+I + EK RR YGG+IGYF+ + D I IR A +E
Sbjct: 415 HAYCACMNMGTLTGAPKIKAMELISKFEKERRGSYGGSIGYFTESNNFDTCIIIRSAYVE 474
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A V+AGAGIV DS+P++E E+ NK +AV++A
Sbjct: 475 NNLATVQAGAGIVLDSVPQEEANESRNKAQAVIQA 509
>sp|Q44689|TRPE_BUCRM ANTHRANILATE SYNTHASE COMPONENT I >gi|1082000|gb|AAB05974.1|
(L43550) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 514
Score = 210 bits (529), Expect = 3e-53
Identities = 124/275 (45%), Positives = 172/275 (62%), Gaps = 11/275 (4%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+ ++ N E+ +++K ++ I G++FQVV SR++ L +P+ Y+KL NPSPY F
Sbjct: 236 LTSNMNNFEYGSIIKKLQKLIQKGEIFQVVPSRKFYLPCP-NPLSAYQKLKKSNPSPYMF 294
Query: 224 ILEFKKI-LVGASPETMGSVEGRTVRIN--PIAGTAPRGKTPEE------DEEIRRRLLS 274
++ K L GASPE+ + +T +I PIAGT PRG+T + D I + +
Sbjct: 295 FMQDKDFTLFGASPESSLKYDEKTRKIELYPIAGTRPRGRTEDGNLDLDLDSRIELEMRT 354
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
+ KE AEH+MLVDLARND+ ++ KPGS + V KYSHV H+ S+VIGEL + D
Sbjct: 355 NHKELAEHLMLVDLARNDLARICKPGSRYVSDLVKVDKYSHVMHLVSKVIGELKEGLDAL 414
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A + GTLTGAPK+RAM++I E EK +R YGGAIGYF+ G D I IR A +E
Sbjct: 415 HAYASCMNMGTLTGAPKVRAMQLIAEYEKEKRGSYGGAIGYFTDLGNLDTCITIRSAYVE 474
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A ++AGAGIV +SIPE E E+ NK +AV+ A
Sbjct: 475 -NIATIQAGAGIVYNSIPEDEVNESLNKAQAVINA 508
>gb|AAG31419.1|AF197464_1 (AF197464) anthranilate synthase component I [Buchnera aphidicola]
Length = 459
Score = 209 bits (527), Expect = 4e-53
Identities = 132/324 (40%), Positives = 186/324 (56%), Gaps = 22/324 (6%)
Query: 122 IYNHGKGELRFYYLRDPSFDPETIVERAKREELKF-------ENGGAEIIRTDANREEFM 174
+++H E Y ++ S + E +++ LK+ +N TDA E++
Sbjct: 131 LFSHNINEK--YRIQKRSIEIENKLKQKLSGRLKYNINISVCKNASLTSNMTDA---EYL 185
Query: 175 EMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVG 233
++++ + +I GD+FQVV SR++ L P+ Y++L NPSPY F ++ K L G
Sbjct: 186 SIIQQLQIFIQKGDIFQVVPSRKFFLPCH-HPLSAYQELKKNNPSPYMFFMQDKMFTLFG 244
Query: 234 ASPETMGSVEGRTVRIN--PIAGTAPRGKTP------EEDEEIRRRLLSDEKERAEHVML 285
ASPE+ +T +I PIAGT PRGKT + D +I + +++KE AEH+ML
Sbjct: 245 ASPESSLKYNNQTRKIELYPIAGTRPRGKTKNGNIDYDLDSKIELEMRTNQKELAEHLML 304
Query: 286 VDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGT 345
VDLARND+ ++ +PGS + V KYSHV H+ S VIG L D A + GT
Sbjct: 305 VDLARNDLARICEPGSRYVSELLKVDKYSHVMHLVSRVIGTLKSHLDALHAYSSCMNMGT 364
Query: 346 LTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAG 405
LTGAPK+RAM++I E EK R YGGAIGYF+ +G D I IR A IE A ++AGAG
Sbjct: 365 LTGAPKVRAMQLISEYEKETRGSYGGAIGYFTDSGDLDTCITIRSAYIENNVATIQAGAG 424
Query: 406 IVADSIPEKEFYETENKMKAVLKA 429
IV SI +E E+ NK KAV+ A
Sbjct: 425 IVLHSIATEEIQESFNKAKAVINA 448
>sp|P42387|TRPE_BUCAP ANTHRANILATE SYNTHASE COMPONENT I >gi|2144529|pir||I40052
anthranilate synthase (EC 4.1.3.27) component I -
Buchnera aphidicola >gi|472881|emb|CAA79931.1| (Z21938)
anthranilate synthase, component I [Buchnera aphidicola]
Length = 515
Score = 209 bits (526), Expect = 6e-53
Identities = 122/275 (44%), Positives = 171/275 (61%), Gaps = 10/275 (3%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+ ++ N E+ +++K ++ I G++FQVV SR++ L +P+ Y+KL NPSPY F
Sbjct: 236 LTSNMNNFEYGTIIKKLQKLIQKGEIFQVVPSRKFYLPCP-NPLSAYQKLKKSNPSPYMF 294
Query: 224 ILEFKKI-LVGASPETMGSVEGRTVRIN--PIAGTAPRGKTPEE------DEEIRRRLLS 274
++ + L GASPE+ + +T +I PIAGT PRGKT + D I + +
Sbjct: 295 FMQDQDFTLFGASPESSLKYDEKTRKIELYPIAGTRPRGKTEDGNLDLDLDSRIELEMRT 354
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
+ KE AEH+MLVDLARND+ ++ KPGS + V +YSHV H+ S VIGEL + D
Sbjct: 355 NHKELAEHLMLVDLARNDLARICKPGSRYVSDLVRVDRYSHVMHLVSRVIGELREGLDAL 414
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A + GTLTGAPK+RAM++I E E +R YGGAIGYF+ G D I IR A +E
Sbjct: 415 HAYASCMNMGTLTGAPKVRAMQLIAEHEGEKRGSYGGAIGYFTDLGNLDTCITIRSAYVE 474
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+ A ++AGAGIV +SIPE E E+ NK +AV+ A
Sbjct: 475 KQVATIQAGAGIVYNSIPENEVNESLNKAQAVINA 509
>gb|AAG31411.1|AF197460_1 (AF197460) anthranilate synthase component I [Buchnera aphidicola]
Length = 457
Score = 208 bits (525), Expect = 7e-53
Identities = 119/267 (44%), Positives = 165/267 (61%), Gaps = 10/267 (3%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
E++ ++++ + +I GD+FQVV SR++ L P+ Y++L + NPSPY F ++ +
Sbjct: 181 EYLSIIQQLQIFIQKGDIFQVVPSRKFFLPC-YHPLSAYQELKTNNPSPYMFFMQDEMFT 239
Query: 231 LVGASPETMGSVEGRT--VRINPIAGTAPRGKTP------EEDEEIRRRLLSDEKERAEH 282
L GASPE+ +T + + PIAGT PRGKT + D I + +++KE AEH
Sbjct: 240 LFGASPESSLKYNNQTRQIELYPIAGTRPRGKTKNGNIDYDLDSRIELEMRTNQKELAEH 299
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDLARND+ ++ +PGS + V KYSHV H+ S VIG L D A +
Sbjct: 300 LMLVDLARNDLARICEPGSRYVAELLKVDKYSHVMHLVSRVIGTLKSHLDALHAYSSCMN 359
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GTLTGAPK+RAM++I E EK R YGGAIGYF+ +G D I IR A IE A ++A
Sbjct: 360 MGTLTGAPKVRAMQLISEYEKETRGSYGGAIGYFTDSGDLDTCITIRSAYIENNVATIQA 419
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
GAGIV +SI +E E+ NK KAV+ A
Sbjct: 420 GAGIVLNSIATEEMQESFNKAKAVINA 446
>sp|Q44691|TRPE_BUCRP ANTHRANILATE SYNTHASE COMPONENT I >gi|1082003|gb|AAB05986.1|
(L43551) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 514
Score = 207 bits (522), Expect = 2e-52
Identities = 121/275 (44%), Positives = 170/275 (61%), Gaps = 10/275 (3%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+ ++ N E+ +++K ++ I G++FQVV SR++ L +P+ Y+KL NPSPY F
Sbjct: 235 LTSNMNNFEYGSIIKKLQKLIQKGEIFQVVPSRKFYLPCP-NPLSAYQKLKKSNPSPYMF 293
Query: 224 ILEFKKI-LVGASPETMGSVEGRTVRIN--PIAGTAPRGKTPEE------DEEIRRRLLS 274
++ + L GASPE+ + +T +I PIAGT PRG+T + D I + +
Sbjct: 294 FMQDQDFTLFGASPESSLKYDEKTRKIELYPIAGTRPRGRTKDGNLDLDLDSRIELEMRT 353
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
+ KE AEH+MLVDLARND+ ++ KPGS + V +YSHV H+ S VIGEL + D
Sbjct: 354 NHKELAEHLMLVDLARNDLARICKPGSRYVSDLVRVDRYSHVMHLVSRVIGELREGLDAL 413
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A + GTLTGAPK+ AM++I E EK +R YGGAIGYF+ G D I IR A +E
Sbjct: 414 HAYASCMNMGTLTGAPKVCAMQLIAEYEKEKRGSYGGAIGYFTDLGNLDTCITIRSAYVE 473
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
R + +AGAGIV +SIPE E E+ NK +AV+ A
Sbjct: 474 KRYCYNQAGAGIVYNSIPEDEVNESLNKAQAVINA 508
>gb|AAG31413.1|AF197461_1 (AF197461) anthranilate synthase component I [Buchnera aphidicola]
Length = 459
Score = 207 bits (522), Expect = 2e-52
Identities = 120/267 (44%), Positives = 163/267 (60%), Gaps = 10/267 (3%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
E++ +++K + +I GD+FQVV SR++ L P+ Y++L NPSPY F ++ +
Sbjct: 183 EYLSIIQKLQTFIQKGDIFQVVPSRKFFLPC-YHPLSAYQELKKNNPSPYMFFMQDEIFT 241
Query: 231 LVGASPETMGSVEGRT--VRINPIAGTAPRGKTP------EEDEEIRRRLLSDEKERAEH 282
L GASPE+ +T + + PIAGT PRGKT + D +I + +++KE AEH
Sbjct: 242 LFGASPESSLKYNNQTRQIELYPIAGTRPRGKTKNGNIDYDLDSKIELEMRTNQKELAEH 301
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDLARND+ ++ +PGS + V KYSHV H+ S VIG L D A
Sbjct: 302 LMLVDLARNDLARICEPGSRYVSELLKVDKYSHVMHLVSRVIGTLKSHLDALHAYSXCMN 361
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GTLTGAPK+RAM++I E EK R YGGAIGYF+ +G D I IR A IE A ++A
Sbjct: 362 MGTLTGAPKVRAMQLISEYEKETRGSYGGAIGYFTDSGDLDTCITIRSAYIEHNVATIQA 421
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
GAGIV SI +E E+ NK KAV+ A
Sbjct: 422 GAGIVLHSIATEEIQESFNKAKAVINA 448
>sp|Q44598|TRPE_BUCSC ANTHRANILATE SYNTHASE COMPONENT I >gi|769831|gb|AAC31215.1|
(U09184) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 530
Score = 206 bits (519), Expect = 4e-52
Identities = 118/276 (42%), Positives = 168/276 (60%), Gaps = 10/276 (3%)
Query: 163 IIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYT 222
I++ + E+ +++++ K+ I G++FQVV SR++ L + + Y L NPSPY
Sbjct: 234 ILKCNRTDREYEKIIKEMKKSIMIGEIFQVVPSRKFYLPC-TNSLAAYDVLKKNNPSPYM 292
Query: 223 FILEFKKI-LVGASPETMGSVE--GRTVRINPIAGTAPRGKTPEE------DEEIRRRLL 273
F ++ L GASPE+ + R + I PIAGT PR + + D I +
Sbjct: 293 FFMQDSNFTLFGASPESSLKYDTLSRKIEIYPIAGTRPRARKIDGSIDLDLDSRIELEMR 352
Query: 274 SDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDM 333
++ KE +EH+MLVDLARND+ K+ PG+ + V KYSHV H+ S V+G+L D D+
Sbjct: 353 TNHKELSEHLMLVDLARNDLAKICDPGTRYVADLTQVDKYSHVMHLVSRVVGKLRLDLDV 412
Query: 334 FDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEI 393
F A +A GTL+GAPKIRAME+I EK +R YGG+IGYF+ +G D I IR A +
Sbjct: 413 FHAYQACMNMGTLSGAPKIRAMELISNAEKEKRGSYGGSIGYFTASGTLDMCIIIRSAYV 472
Query: 394 EGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
E A ++ GAGIV DSIP+ E E++NK KAVL+A
Sbjct: 473 ENNIATIQVGAGIVLDSIPQLEVDESKNKAKAVLQA 508
>pir||H81376 anthranilate synthase (EC 4.1.3.27) chain I Cj0345 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967820|emb|CAB74182.1| (AL139075) putative
anthranilate synthase component I [Campylobacter jejuni]
Length = 416
Score = 205 bits (517), Expect = 6e-52
Identities = 125/304 (41%), Positives = 180/304 (59%), Gaps = 22/304 (7%)
Query: 132 FYYLRDPSFDPETIVERAKREELKFENGGAEIIRT-DANREEFMEMVEKGKEYIFAGDVF 190
F YL+D D E + ++ K + EI+ + + + +F++M EK KEY+ +GD+F
Sbjct: 122 FEYLKD---DIEPMKKKQKND--------FEILNSLEDEKNDFLKMCEKAKEYLLSGDIF 170
Query: 191 QVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRI 249
QVVLS++ ++ V+ + Y L ++NPS Y F K +++G+SPE + ++ R + +
Sbjct: 171 QVVLSKQLCIKHQVNAFDYYESLSALNPSAYMFYFPSKYGVVLGSSPEFLLKIKKREIYL 230
Query: 250 NPIAGTAPRGKTPEEDEEI---RRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVR 306
PIAGT + E + ++ + LLSDEKE +EH MLVDLARND K V+
Sbjct: 231 APIAGT----RNLENNCDLLALEKDLLSDEKELSEHKMLVDLARNDASKFGTQTRVE--N 284
Query: 307 FFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRR 366
F +IK V HI SEV + +D +FD IEA FPAGTL+GAPKIRA+EI ELE R
Sbjct: 285 LFSIIKNKFVMHIVSEVYANMKEDASIFDVIEAVFPAGTLSGAPKIRALEITSELEDCDR 344
Query: 367 RVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAV 426
+YGGA+G+ + AI IR A KA++ +GAGIV S +KE+ E K KA+
Sbjct: 345 GIYGGAVGFLNFNEDITLAILIRCAFFTQDKAYLASGAGIVLQSESQKEYAEICAKRKAL 404
Query: 427 LKAF 430
L AF
Sbjct: 405 LVAF 408
>sp|P43761|TRPE_HAEIN ANTHRANILATE SYNTHASE COMPONENT I >gi|1073849|pir||C64121
anthranilate synthase (EC 4.1.3.27) component I -
Haemophilus influenzae (strain Rd KW20)
>gi|1574221|gb|AAC23033.1| (U32819) anthranilate
synthase component I (trpE) [Haemophilus influenzae Rd]
Length = 518
Score = 205 bits (516), Expect = 9e-52
Identities = 119/275 (43%), Positives = 166/275 (60%), Gaps = 10/275 (3%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
++T+ + EF +V+ K +I GDVFQ+V SR + L + + Y +L NPSPY F
Sbjct: 236 VKTNFDDPEFTGIVKALKHHINIGDVFQIVPSRRFSLACP-NTLASYAQLKQNNPSPYMF 294
Query: 224 ILEFKK-ILVGASPETM--GSVEGRTVRINPIAGTAPRGKT------PEEDEEIRRRLLS 274
+ + IL GASPE+ + E R + I PIAG+ PRG PE D + L
Sbjct: 295 YMNDEDFILFGASPESALKYAPENRQLEIYPIAGSRPRGFDAHGNIDPELDARLELELRL 354
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
D KE+AEH+MLVDLARND+ +V + G+ K+ V +YSH+ H+ S V+G+L + D
Sbjct: 355 DHKEQAEHLMLVDLARNDIARVCQSGTRKVAELMQVDRYSHIMHLVSRVVGKLRPELDAL 414
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A +A GTLTGAPKI+AM++I + E+ +R YGGA+GY + G+ D I IR A ++
Sbjct: 415 HAYQACMNMGTLTGAPKIKAMQLIYQFEQQKRHSYGGAVGYLTSDGHFDTCIVIRSAFVQ 474
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
AHV+AG G V DS P+ E ET +K AVLKA
Sbjct: 475 NGMAHVQAGCGEVLDSDPQMEADETRHKAAAVLKA 509
>gb|AAF13810.1|AF130815_2 (AF130815) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 522
Score = 205 bits (516), Expect = 9e-52
Identities = 117/266 (43%), Positives = 165/266 (61%), Gaps = 10/266 (3%)
Query: 173 FMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-L 231
+++++E+ ++ I G++FQVV SR + L +D + Y L NPSPY F ++ L
Sbjct: 244 YIKIIEEMQKLILIGEIFQVVPSRRFYLPC-IDSLAAYDVLKKNNPSPYMFFMQDSHFTL 302
Query: 232 VGASPETM--GSVEGRTVRINPIAGTAPRGKTP------EEDEEIRRRLLSDEKERAEHV 283
GASP + V R + I PIAGT PR + + D I + ++ KE AEH+
Sbjct: 303 FGASPVSALKYDVSSRQIEIYPIAGTRPRERKINGSLDLDLDSRIELEMRTNHKELAEHL 362
Query: 284 MLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPA 343
MLVDLARND+ ++ PG+ + V +YSHV H+ S V+G+L + D+F A +A
Sbjct: 363 MLVDLARNDLARICDPGTRYVANLTQVDRYSHVMHLVSRVVGKLKSNLDVFHAYQACMNM 422
Query: 344 GTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAG 403
GTL+GAPKIRAME+I +EK +R YGG+IGYF+ +G D I IR A +E A V+AG
Sbjct: 423 GTLSGAPKIRAMELISYVEKEKRGSYGGSIGYFTASGALDTCIVIRSAYVENNIAIVQAG 482
Query: 404 AGIVADSIPEKEFYETENKMKAVLKA 429
AGIV DSIP+ E E++NK KAVL+A
Sbjct: 483 AGIVVDSIPQSEADESKNKAKAVLQA 508
>gb|AAG18942.1| (AE004995) anthranilate synthase alpha chain; TrpE2 [Halobacterium
sp. NRC-1]
Length = 488
Score = 205 bits (516), Expect = 9e-52
Identities = 119/265 (44%), Positives = 154/265 (57%), Gaps = 1/265 (0%)
Query: 168 ANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF 227
A R F V + ++ I GD FQ +S + V PV ++ L NP+PY+ I+EF
Sbjct: 208 AGRAAFESRVRRIQDAIRDGDTFQANVSHRLDAPAAVHPVAVFEALRDTNPAPYSGIVEF 267
Query: 228 KKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLV 286
+ LV ASPE + + GR + PIAGT PRG TP ED+ R L +D+KERAEH MLV
Sbjct: 268 PGVDLVSASPELLLARRGRELTTEPIAGTRPRGATPAEDDAARAALRADDKERAEHAMLV 327
Query: 287 DLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTL 346
DL RND+ KVS+ GSV + + V YS V H+ SEV G L D + DAI A FP GT+
Sbjct: 328 DLERNDLGKVSEYGSVAVPDYRRVDAYSEVLHLVSEVTGRLRDSCSLRDAIAAVFPGGTI 387
Query: 347 TGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGI 406
TGAPK R M +ID +E +RR Y G++ G A +I IR H+R GAGI
Sbjct: 388 TGAPKPRTMALIDTVEATRRGPYTGSLAAIGFDGDATLSITIRTLVRRAATYHLRVGAGI 447
Query: 407 VADSIPEKEFYETENKMKAVLKAFG 431
V DS P E+ ET K +A++ A G
Sbjct: 448 VHDSTPAAEYDETLAKARALVTALG 472
>gb|AAG31410.1| (AF197459) anthranilate synthase component I [Buchnera aphidicola]
Length = 456
Score = 204 bits (514), Expect = 1e-51
Identities = 118/277 (42%), Positives = 167/277 (59%), Gaps = 10/277 (3%)
Query: 162 EIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+++ ++ +E++ +++K + I GD+FQVV SR++ L + Y++L NPSPY
Sbjct: 173 DLLTSNMTDDEYLSIIKKLQILIQKGDIFQVVPSRKFFLPC-YHALSAYQELKKSNPSPY 231
Query: 222 TFILEFKKI-LVGASPETMGSVEGRT--VRINPIAGTAPRGKTP------EEDEEIRRRL 272
F ++ + L GASPE+ +T + + PIAGT PRGKT + D I +
Sbjct: 232 MFFMQDEIFTLFGASPESSLKYNNKTRQIELYPIAGTRPRGKTKNGSIDYDLDSRIELEM 291
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+++KE AEH+MLVDLARND+ ++ +PGS + V KYSHV H+ S VIG L D
Sbjct: 292 RTNQKELAEHLMLVDLARNDLARICEPGSRYVAELLKVDKYSHVMHLVSRVIGTLKSHLD 351
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
A + GTLTGAPK+RAM++I E EK R YGGAIGYF+ G D I IR A
Sbjct: 352 ALHAYSSCMNMGTLTGAPKVRAMQLISEYEKETRGSYGGAIGYFTDAGDLDTCITIRSAY 411
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
IE A ++AGAGIV SI ++E E+ NK +AV+ A
Sbjct: 412 IEQNIATIQAGAGIVLQSIAKEEIQESFNKAQAVINA 448
>gi|6320935 anthranilate synthase Component I; Trp2p [Saccharomyces cerevisiae]
>gi|731012|sp|P00899|TRPE_YEAST ANTHRANILATE SYNTHASE
COMPONENT I >gi|1070510|pir||NNBY1 anthranilate synthase
(EC 4.1.3.27) component I - yeast (Saccharomyces
cerevisiae) >gi|4670|emb|CAA48402.1| (X68327)
anthranilate synthase (component 1) [Saccharomyces
cerevisiae] >gi|603328|gb|AAB64645.1| (U18839) Trp2p:
anthranilate synthase component I [Saccharomyces
cerevisiae]
Length = 507
Score = 203 bits (511), Expect = 3e-51
Identities = 112/267 (41%), Positives = 163/267 (60%), Gaps = 3/267 (1%)
Query: 162 EIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+ ++ +E + V K++I GD+ Q V S+ + + P +YR L ++NPSPY
Sbjct: 222 QTFESNVGKEGYENHVSTLKKHIKKGDIIQGVPSQRVARPTSLHPFNIYRHLRTVNPSPY 281
Query: 222 TFILEFKKI-LVGASPETMGSVEGRT-VRINPIAGTAPRGKTPEEDEEIRRRLLSDEKER 279
F ++ ++GASPE + + + V +PIAGT RG T EED+ + +L K+R
Sbjct: 282 LFYIDCLDFQIIGASPELLCKSDSKNRVITHPIAGTVKRGATTEEDDALADQLRGSLKDR 341
Query: 280 AEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEA 339
AEHVMLVDLARND+ ++ P + + + + K+SHVQH+ S+V G L +K FDA +
Sbjct: 342 AEHVMLVDLARNDINRICDPLTTSVDKLLTIQKFSHVQHLVSQVSGVLRPEKTRFDAFRS 401
Query: 340 SFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYA-DFAIAIRMAEIEGRKA 398
FPAGT++GAPK+RAME+I ELE RR VY GA+G++S G D IA+R + A
Sbjct: 402 IFPAGTVSGAPKVRAMELIAELEGERRGVYAGAVGHWSYDGKTMDNCIALRTMVYKDGIA 461
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKA 425
+++AG GIV DS E+ ET NKM A
Sbjct: 462 YLQAGGGIVYDSDEYDEYVETMNKMMA 488
>emb|CAA23666.1| (V00368) trpE [Escherichia coli] >gi|43202|emb|CAA23671.1| (V00372)
trpE [Escherichia coli] >gi|147955|gb|AAA57297.1|
(J01714) anthranilate synthase component I [Escherichia
coli]
Length = 520
Score = 203 bits (510), Expect = 4e-51
Identities = 122/277 (44%), Positives = 164/277 (59%), Gaps = 12/277 (4%)
Query: 164 IRTDANR--EEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+R + N+ EEF +V ++ I AG++FQVV SR + L P+ Y L NPSPY
Sbjct: 234 MRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCP-SPLAAYYVLKKSNPSPY 292
Query: 222 TFILEFKKI-LVGASPETMGSVEG--RTVRINPIAGTAPRGKTPEE------DEEIRRRL 272
F ++ L GASPE+ + R + I PIAGT PRG+ + D I +
Sbjct: 293 MFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGRRADGSLDRDLDSRIELEM 352
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+D KE +EH+MLVDLARND+ ++ PGS + V +YS+V H+ S V+GEL D D
Sbjct: 353 RTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDRYSYVMHLVSRVVGELRHDLD 412
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
A A GTL+GAPK+RAM++I E E RR YGGA+GYF+ G D I IR A
Sbjct: 413 ALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYGGAVGYFTAHGDLDTCIVIRSAL 472
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+E A V+AGAG+V DS+P+ E ET NK +AVL+A
Sbjct: 473 VENGIATVQAGAGVVLDSVPQSEADETRNKARAVLRA 509
>sp|P00895|TRPE_ECOLI ANTHRANILATE SYNTHASE COMPONENT I >gi|7428353|pir||NNEC1
anthranilate synthase (EC 4.1.3.27) component I -
Escherichia coli >gi|1742057|dbj|BAA14799.1| (D90764)
Anthranilate synthase component I (EC 4.1.3.27).
[Escherichia coli] >gi|1742073|dbj|BAA14814.1| (D90765)
Anthranilate synthase component I (EC 4.1.3.27).
[Escherichia coli] >gi|1787518|gb|AAC74346.1| (AE000224)
anthranilate synthase component I [Escherichia coli K12]
Length = 520
Score = 203 bits (510), Expect = 4e-51
Identities = 122/277 (44%), Positives = 164/277 (59%), Gaps = 12/277 (4%)
Query: 164 IRTDANR--EEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+R + N+ EEF +V ++ I AG++FQVV SR + L P+ Y L NPSPY
Sbjct: 234 MRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCP-SPLAAYYVLKKSNPSPY 292
Query: 222 TFILEFKKI-LVGASPETMGSVEG--RTVRINPIAGTAPRGKTPEE------DEEIRRRL 272
F ++ L GASPE+ + R + I PIAGT PRG+ + D I +
Sbjct: 293 MFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGRRADGSLDRDLDSRIELEM 352
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+D KE +EH+MLVDLARND+ ++ PGS + V +YS+V H+ S V+GEL D D
Sbjct: 353 RTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDRYSYVMHLVSRVVGELRHDLD 412
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
A A GTL+GAPK+RAM++I E E RR YGGA+GYF+ G D I IR A
Sbjct: 413 ALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYGGAVGYFTAHGDLDTCIVIRSAL 472
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+E A V+AGAG+V DS+P+ E ET NK +AVL+A
Sbjct: 473 VENGIATVQAGAGVVLDSVPQSEADETRNKARAVLRA 509
>gb|AAF82323.1|AD001677_1 (AD001677) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 528
Score = 203 bits (510), Expect = 4e-51
Identities = 119/267 (44%), Positives = 163/267 (60%), Gaps = 10/267 (3%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
E++ +++K + +I GD+FQVV SR++ L + Y++L NPSPY F ++ +
Sbjct: 252 EYLSIIKKLQIFIQKGDIFQVVPSRKFFLPC-YHALSAYQELKKSNPSPYMFFMQDEIFT 310
Query: 231 LVGASPETMGSV--EGRTVRINPIAGTAPRGKTP------EEDEEIRRRLLSDEKERAEH 282
L GASPE+ + R + + PIAGT PRGKT + D +I + +++KE +EH
Sbjct: 311 LFGASPESSLKYNHQNRQIELYPIAGTRPRGKTKNGNIDYDLDSKIELEMRTNQKELSEH 370
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDLARND+ ++ +PGS + V KYSHV H+ S VIG L D A +
Sbjct: 371 LMLVDLARNDLARICEPGSRYVAELLKVDKYSHVMHLVSRVIGTLKSHLDALHAYSSCMN 430
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GTLTGAPK+RAM++I E EK R YGGAIGYF+ +G D I IR A IE A V+A
Sbjct: 431 MGTLTGAPKVRAMQLIAEYEKETRGSYGGAIGYFTDSGDLDTCITIRSAYIEQNIATVQA 490
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
GAGIV SI E+E E+ NK AV+ A
Sbjct: 491 GAGIVLHSIAEEEIQESLNKATAVINA 517
>gb|AAF01062.1|AF189258_1 (AF189258) aminase [Streptomyces venezuelae]
Length = 391
Score = 200 bits (504), Expect = 2e-50
Identities = 103/252 (40%), Positives = 155/252 (60%), Gaps = 2/252 (0%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+R +R F++ + ++I GD++Q+ + +R+ + PV++YR+L NPSP+ +
Sbjct: 79 VRDSVSRSTFLDWAGRCLDHIAVGDIYQIQIGHRIDVRTALGPVDVYRRLRGRNPSPHMY 138
Query: 224 IL-EFKKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIR-RRLLSDEKERAE 281
+L + L+GASPE +E + + PIAGTA R E+ E R + + EKERAE
Sbjct: 139 LLPRAGRTLIGASPELFFRIEDGAIVMRPIAGTARRHPDDHEENERRVKEMRESEKERAE 198
Query: 282 HVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF 341
H+MLVDL RND+ +V +P + R V +SHV H+ S V GEL + D + A+ A+F
Sbjct: 199 HIMLVDLCRNDIGRVCRPSVQPVDRLMAVETFSHVFHLVSTVSGELEPEVDPWQAVRATF 258
Query: 342 PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVR 401
PAGT+TGAPK+RAMEIID LE+ R Y GA+G + G+++ A+ IR E +G +
Sbjct: 259 PAGTMTGAPKLRAMEIIDGLEQEHRGAYAGAVGVVDVRGWSELALCIRTIEYDGAVYSTQ 318
Query: 402 AGAGIVADSIPE 413
+ AG+VA S PE
Sbjct: 319 SSAGLVAQSDPE 330
>pir||A39812 anthranilate synthase (EC 4.1.3.27) component I (trpE) - Salmonella
typhimurium
Length = 520
Score = 200 bits (503), Expect = 3e-50
Identities = 120/277 (43%), Positives = 164/277 (58%), Gaps = 12/277 (4%)
Query: 164 IRTDANREE--FMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+R + N+ + F +V + ++ I AG++FQVV SR + L P+ Y L NPSPY
Sbjct: 234 MRCECNQSDDAFGAVVRQLQKAIRAGEIFQVVPSRRFSLPCP-SPLAAYYVLKKSNPSPY 292
Query: 222 TFILEFKKI-LVGASPETMGSVEG--RTVRINPIAGTAPRGKTPEE------DEEIRRRL 272
F ++ L GASPE+ + R + I PIAGT PRG+ + D I +
Sbjct: 293 MFFMQDNDFTLFGASPESSLKYDAASRQIEIYPIAGTRPRGRRADGTLDRDLDSRIELDM 352
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+D KE +EH+MLVDLARND+ ++ PGS + V +YS+V H+ S V+GEL D D
Sbjct: 353 RTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDRYSYVMHLVSRVVGELRHDLD 412
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
A A GTL+GAPK+RAM++I E + RR YGGA+GYF+ G D I IR A
Sbjct: 413 ALHAYRACMNMGTLSGAPKVRAMQLIAEADGQRRGSYGGAVGYFTAHGDLDTCIVIRSAL 472
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+E A V+AGAGIV DS+P+ E ET NK +AVL+A
Sbjct: 473 VENGIATVQAGAGIVLDSVPQSEADETRNKARAVLRA 509
>sp|Q44697|TRPE_BUCDN ANTHRANILATE SYNTHASE COMPONENT I >gi|1374672|gb|AAB02275.1|
(L46769) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 519
Score = 199 bits (502), Expect = 4e-50
Identities = 118/276 (42%), Positives = 164/276 (58%), Gaps = 10/276 (3%)
Query: 163 IIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYT 222
++ + + E++ +++K + I G++FQVV SR++ L +P+ Y+KL NPSPY
Sbjct: 237 MLTANMSDEQYCSIIKKLQILIRKGEIFQVVPSRKFFLPCS-NPLSAYQKLKKSNPSPYM 295
Query: 223 FILEFKKI-LVGASPETMGSVEGRT--VRINPIAGTAPRGKTPEE------DEEIRRRLL 273
F ++ K L GASPE+ + T V + PIAGT PRG+ + D I +
Sbjct: 296 FFMQDKDFTLFGASPESSLKYDDTTRQVELYPIAGTRPRGRNMDGTLNLDLDSRIELEMR 355
Query: 274 SDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDM 333
++ KE AEH+MLVDLARND+ ++ +PGS + V KY HV H+ S V+G L + D
Sbjct: 356 TNHKELAEHLMLVDLARNDLARICEPGSRYVSDLVRVDKYPHVMHLVSRVVGTLKPELDA 415
Query: 334 FDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEI 393
A A GTLTGAPKIRAME+I E E +R YGGAIGYF+ G D I IR A +
Sbjct: 416 LHAYAACMNMGTLTGAPKIRAMELIAEYEMEQRGSYGGAIGYFTDLGNLDTCITIRSAYV 475
Query: 394 EGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
E A +++G+GIV +SIPE E E NK K V+ A
Sbjct: 476 EDNIATIQSGSGIVYNSIPEDEVKEGINKAKRVINA 511
>gb|AAG31408.1| (AF197458) anthranilate synthase component I [Buchnera aphidicola]
Length = 455
Score = 199 bits (502), Expect = 4e-50
Identities = 114/267 (42%), Positives = 162/267 (59%), Gaps = 10/267 (3%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
E+ +++K + +I G++FQ+V SR++ L D + Y++L NPSPY F ++ +
Sbjct: 179 EYATIIKKLQMFIQKGEIFQIVPSRKFFLPCH-DSLSAYQELKRSNPSPYMFFMQDEIFT 237
Query: 231 LVGASPETMGSVEG--RTVRINPIAGTAPRGKTPEE------DEEIRRRLLSDEKERAEH 282
L GASPE+ + R + + PIAGT PRG+T + D I + +++KE AEH
Sbjct: 238 LFGASPESSLKYDPLTRQIELYPIAGTRPRGRTKDGTLDWDLDSRIELEMRTNQKELAEH 297
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDLARND+ ++ +PGS + V KYSHV H+ S+V+G L D A +
Sbjct: 298 LMLVDLARNDLARICEPGSRYVSDLVKVDKYSHVMHLVSKVVGRLRAPLDALHAYSSCMN 357
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GTLTGAPK+RAM++I E E R YGGAIGYF+ G+ D I IR +E A ++A
Sbjct: 358 MGTLTGAPKVRAMQLIAEYEHETRGSYGGAIGYFTDAGHLDTCIVIRSXYVENNIATIQA 417
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
GAGIV SIPE+E E+ NK AV+ A
Sbjct: 418 GAGIVLHSIPEEEIQESLNKATAVINA 444
>sp|P09785|PHNA_PSEAE ANTHRANILATE SYNTHASE COMPONENT I >gi|94751|pir||A35116
anthranilate synthase (EC 4.1.3.27) component I -
Pseudomonas aeruginosa >gi|11347432|pir||B83519
anthranilate synthase component I PA1001 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|151457|gb|AAA88448.1| (M33810) anthranilate synthase
alpha subunit [Pseudomonas aeruginosa]
>gi|9946911|gb|AAG04390.1|AE004533_1 (AE004533)
anthranilate synthase component I [Pseudomonas
aeruginosa]
Length = 530
Score = 198 bits (498), Expect = 1e-49
Identities = 121/274 (44%), Positives = 154/274 (56%), Gaps = 10/274 (3%)
Query: 165 RTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFI 224
+ D + F VE+ + ++ AGDVFQ+V SR + + DP YR+L NPSPY F
Sbjct: 240 QVDLDDASFARQVERLQAHVRAGDVFQIVPSRSFSMPC-ADPWRAYRQLCLRNPSPYRFF 298
Query: 225 LEFKKI-LVGASPETM--GSVEGRTVRINPIAGTAPRGKTP------EEDEEIRRRLLSD 275
L+ L GASPE+ E R V + PIAGT PRG+ E D + L D
Sbjct: 299 LDAGDFCLFGASPESALKYDAESREVELYPIAGTRPRGRDARGAIDAELDNRLEAELRLD 358
Query: 276 EKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFD 335
KE AEH+MLVDLARND+ +V + G+ ++ V +YSHV H+ S V GEL + D
Sbjct: 359 AKEIAEHMMLVDLARNDLARVCRSGTRQVRDMLKVDRYSHVMHLVSRVAGELHGELDALH 418
Query: 336 AIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEG 395
A A GTL GAPK+RAM+++ + E R YGGAIG G D +I IR AE+
Sbjct: 419 AYRACLNMGTLVGAPKVRAMQLLRQYEDGYRGSYGGAIGILDSAGNLDTSIVIRSAEVRE 478
Query: 396 RKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A VRAGAG+V DS P E ET NK AVL A
Sbjct: 479 GIARVRAGAGVVLDSDPRLEAEETRNKALAVLTA 512
>gb|AAF82316.1|L81123_1 (L81123) anthranilate synthase large subunit [Buchnera aphidicola]
Length = 521
Score = 198 bits (498), Expect = 1e-49
Identities = 118/267 (44%), Positives = 159/267 (59%), Gaps = 10/267 (3%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
E+ ++++ +I GD+FQVV SR++ L + Y++L NPSPY F ++ +
Sbjct: 245 EYASIIKELHLFIQKGDIFQVVPSRKFFLPC-YHSLAAYQELKISNPSPYMFFMQDEIFT 303
Query: 231 LVGASPETMGSVEGRT--VRINPIAGTAPRGKTPEE------DEEIRRRLLSDEKERAEH 282
L GASPE+ + T + PIAGT PRGK + D I + +++KE AEH
Sbjct: 304 LFGASPESSLKYDETTRQAELYPIAGTRPRGKKKDGTIDYDLDSRIELEMRTNQKELAEH 363
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDLARND+ ++ +PGS + V KYSHV H+ S VIG L D D A A
Sbjct: 364 LMLVDLARNDLARICEPGSRYVSELVKVDKYSHVIHLVSRVIGTLKSDLDALHAYSACMN 423
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GTLTG PK+RAM++I EK R YGGAIGYF+ TG D I IR A +E A ++A
Sbjct: 424 MGTLTGVPKVRAMQLIARYEKGTRGSYGGAIGYFTDTGQLDTCITIRSAYVEQNMATIQA 483
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
GAGIV +SI E+E E+ NK KAV+ A
Sbjct: 484 GAGIVLNSIAEEEIKESLNKAKAVINA 510
>gb|AAG31415.1|AF197462_1 (AF197462) anthranilate synthase component I [Buchnera aphidicola]
Length = 451
Score = 198 bits (497), Expect = 1e-49
Identities = 115/273 (42%), Positives = 166/273 (60%), Gaps = 13/273 (4%)
Query: 166 TDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFIL 225
TDA +++ +++ + +I GD+FQVV SR++ L P+ Y++L NPSPY F +
Sbjct: 176 TDA---QYLSIIKHMQAFIQKGDIFQVVPSRKFFLPCQY-PLLAYQELKKSNPSPYMFFM 231
Query: 226 EFKK-ILVGASPETMGSVE--GRTVRINPIAGTAPRGKTPEE------DEEIRRRLLSDE 276
+ + IL GASPE+ + R + + PIAGT RGK + D I + +++
Sbjct: 232 QDEAFILFGASPESSLKYDETNRKIELYPIAGTRSRGKNRDGTINYDLDSRIELEMRTNQ 291
Query: 277 KERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDA 336
KE +EH+MLVDL RND+ ++ +PGS + V KYSHV H+ S+V+G L + D+ A
Sbjct: 292 KELSEHLMLVDLXRNDLARICEPGSRYVAELLKVDKYSHVMHLVSKVVGTLKSNLDVLHA 351
Query: 337 IEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGR 396
+ GTLTGAPK+RAME+I + EK R YGGAIGY + +G+ D I IR A +E
Sbjct: 352 YASCMNMGTLTGAPKVRAMELIAQHEKETRGSYGGAIGYLTDSGHLDTCITIRSAYVEKN 411
Query: 397 KAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A V+AGAG+V SI E+E E+ NK AV+ A
Sbjct: 412 IATVQAGAGVVLHSIAEEEIQESINKATAVINA 444
>gi|10957100 anthranilate synthase large subunit [Buchnera sp. APS]
>gi|11182451|sp|Q44695|TRPE_BUCAI ANTHRANILATE SYNTHASE
COMPONENT I >gi|7707814|dbj|BAA95417.1| (AP001070)
anthranilate synthase large subunit [Buchnera sp. APS]
Length = 521
Score = 197 bits (496), Expect = 2e-49
Identities = 114/267 (42%), Positives = 163/267 (60%), Gaps = 10/267 (3%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-I 230
++ ++K ++ I G++FQVV SR++ L D + + Y++L NPSPY F ++ + I
Sbjct: 245 QYSSTIKKLQKLIQKGEIFQVVPSRKFFLPCD-NSLSAYQELKKSNPSPYMFFMQDEDFI 303
Query: 231 LVGASPETMGSVE--GRTVRINPIAGTAPRGKTPEE------DEEIRRRLLSDEKERAEH 282
L GASPE+ + R + + PIAGT PRG+ + D I + ++ KE AEH
Sbjct: 304 LFGASPESSLKYDEKNRQIELYPIAGTRPRGRKKDGTLDLDLDSRIELEMRTNHKELAEH 363
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDLARND+ ++ +PGS + V KYSHV H+ S+V+G+L D A +
Sbjct: 364 LMLVDLARNDLARICEPGSRYVSDLVKVDKYSHVMHLVSKVVGQLKYGLDALHAYSSCMN 423
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GTLTGAPK+RAM++I E E R YGGAIGYF+ G D I IR A +E A ++A
Sbjct: 424 MGTLTGAPKVRAMQLIAEYEGEGRGSYGGAIGYFTDLGNLDTCITIRSAYVESGVATIQA 483
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
GAG+V +SIPE E E+ NK +AV+ A
Sbjct: 484 GAGVVFNSIPEDEVKESLNKAQAVINA 510
>gb|AAG31417.1|AF197463_1 (AF197463) anthranilate synthase component I [Buchnera aphidicola]
Length = 448
Score = 197 bits (496), Expect = 2e-49
Identities = 115/277 (41%), Positives = 167/277 (59%), Gaps = 10/277 (3%)
Query: 162 EIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+++ ++ E++ ++++ ++ I GD+FQVV SR++ L + Y++L PSPY
Sbjct: 162 DLLTSNMTDYEYLSIIQQLQKLIQKGDIFQVVPSRKFFLPC-YHALFSYQELKKSXPSPY 220
Query: 222 TFILEFKKI-LVGASPETMGSVEGRT--VRINPIAGTAPRGKTP------EEDEEIRRRL 272
F ++ + L GASPE+ +T + + PIAGT PRGKT + B I +
Sbjct: 221 MFFMQDEIFTLFGASPESSLKYNNKTRQIELYPIAGTRPRGKTQNGSIDYDLBSRIELEM 280
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+++KE AEH+MLVDLARND+ ++ +PGS + V KYSHV H+ S VIG L D
Sbjct: 281 RTNQKELAEHLMLVDLARNDLARICEPGSRYVAELLKVDKYSHVMHLVSRVIGTLKSHLD 340
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
A + GTLTGAPK+RAM++I E EK R YGGAIGYF+ +G D I IR A
Sbjct: 341 ALHAYSSCMNMGTLTGAPKVRAMQLIAEYEKETRGSYGGAIGYFTDSGDLDTCITIRSAY 400
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
IE A ++AGAGIV SI ++E E+ NK +AV+ A
Sbjct: 401 IEQNIATIQAGAGIVLHSIAKEEIQESFNKAQAVINA 437
>sp|P74130|TRE2_SYNY3 ANTHRANILATE SYNTHASE COMPONENT I-LIKE PROTEIN
>gi|7436741|pir||S75655 anthranilate synthase (EC
4.1.3.27) component I - Synechocystis sp. (strain PCC
6803) >gi|1653301|dbj|BAA18216.1| (D90912) anthranilate
synthase component I [Synechocystis sp.]
Length = 485
Score = 197 bits (495), Expect = 2e-49
Identities = 109/264 (41%), Positives = 161/264 (60%), Gaps = 3/264 (1%)
Query: 169 NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSD--VDPVELYRKLISINPSPYTFILE 226
+++++ MV + K+YI AGD+FQ L+ ++ +++ ++ ++Y+ L +INPSP+
Sbjct: 218 DQDQYETMVNQAKQYIKAGDIFQANLTLRFIAKTEQKLNSWQVYQHLQTINPSPFASYWR 277
Query: 227 FK-KILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVML 285
+V SPE + +EG + PIAGT RGK EDE++ + LL + KE AEH+ML
Sbjct: 278 SPWGDVVSCSPERLVKLEGNVAQTRPIAGTRARGKNLAEDEQLLQELLVNTKELAEHIML 337
Query: 286 VDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGT 345
VDL RND+ +V G+V++ + +YSHV H+ S V G L DK D ++A FP GT
Sbjct: 338 VDLERNDLGRVCTWGTVEVDELLAIERYSHVSHLVSNVKGILQPDKTGVDLVKALFPGGT 397
Query: 346 LTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAG 405
+TG PKIR +EII+ELE RR ++ G+ GY+ G D I IR + + GAG
Sbjct: 398 ITGCPKIRCLEIIEELEPVRRSLFYGSCGYWDQRGNLDLNILIRTLLFTSGQVTGQVGAG 457
Query: 406 IVADSIPEKEFYETENKMKAVLKA 429
IVADS P KE+ E+ K KA+L A
Sbjct: 458 IVADSDPAKEWLESLQKAKALLAA 481
>pir||E35116 anthranilate synthase (EC 4.1.3.27) alpha chain - Pseudomonas
aeruginosa >gi|151460|gb|AAA88451.1| (M33811)
anthranilate synthase alpha subunit [Pseudomonas
aeruginosa]
Length = 530
Score = 196 bits (493), Expect = 4e-49
Identities = 121/274 (44%), Positives = 153/274 (55%), Gaps = 10/274 (3%)
Query: 165 RTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFI 224
+ D + F VE+ + ++ AGDVFQ+V SR + + DP YR+L NPSPY F
Sbjct: 240 QVDLDDASFARQVERLQAHVRAGDVFQIVPSRSFSMPC-ADPWRAYRQLCLRNPSPYRFF 298
Query: 225 LEFKKI-LVGASPETM--GSVEGRTVRINPIAGTAPRGKTP------EEDEEIRRRLLSD 275
L+ L GASPE+ E R V + PIAGT PRG E D + L D
Sbjct: 299 LDAGDFCLFGASPESALKYDAESREVELYPIAGTRPRGCDARGAIDAELDNRLEAELRLD 358
Query: 276 EKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFD 335
KE AEH+MLVDLARND+ +V + G+ ++ V +YSHV H+ S V GEL + D
Sbjct: 359 AKEIAEHMMLVDLARNDLARVCRSGTRQVRDMLKVDRYSHVMHLVSRVAGELHGELDALH 418
Query: 336 AIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEG 395
A A GTL GAPK+RAM+++ + E R YGGAIG G D +I IR AE+
Sbjct: 419 AYRACLNMGTLVGAPKVRAMQLLRQYEDGYRGSYGGAIGILDSAGNLDTSIVIRSAEVRE 478
Query: 396 RKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A VRAGAG+V DS P E ET NK AVL A
Sbjct: 479 GIARVRAGAGVVLDSDPRLEAEETRNKALAVLTA 512
>pir||A82777 anthranilate synthase component I XF0674 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9105554|gb|AAF83484.1|AE003911_6 (AE003911)
anthranilate synthase component I [Xylella fastidiosa]
Length = 452
Score = 196 bits (493), Expect = 4e-49
Identities = 113/271 (41%), Positives = 160/271 (58%), Gaps = 4/271 (1%)
Query: 166 TDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLR--SDVDPVELYRKLISINPSPYT- 222
T+ +F+ E+ +Y+ GDVFQ +SR + R + +DP LY +L NP+P++
Sbjct: 183 TEDEPSQFIANAERVLDYLREGDVFQANISRLWEARFTTALDPAALYMRLRVANPAPFSG 242
Query: 223 FILEFKKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEH 282
+ + +V +SPE + SV+G ++ PIAGT PR ++ IR L++ KERAEH
Sbjct: 243 LFVAHGRAVVSSSPERLISVQGARIQTRPIAGTRPRFVGDDDAARIRE-LVNHPKERAEH 301
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
VML+DL RND+ +V PG+V++ V Y+HV HI S V G L + + I A FP
Sbjct: 302 VMLIDLERNDLGRVCVPGTVEVDELMTVESYAHVHHIVSNVRGWLPTGRTPGEIIRAVFP 361
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GT+TG PK+R M+II +LE+ R Y GA G+ + G D I IR AEI+G R
Sbjct: 362 GGTITGCPKVRCMQIIAQLEQVARGAYTGAFGWLNCDGDLDLNILIRTAEIDGVTVRFRN 421
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKAFGVI 433
GAGIV +S+PE+E ET K VL+A VI
Sbjct: 422 GAGIVINSLPERELDETRAKATGVLRALHVI 452
>gb|AAD09346.1| (L43555) anthranilate synthase large subunit [Buchnera aphidicola]
Length = 521
Score = 195 bits (491), Expect = 7e-49
Identities = 113/267 (42%), Positives = 163/267 (60%), Gaps = 10/267 (3%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-I 230
++ ++K ++ I G++FQVV SR++ L + + + Y++L NPSPY F ++ + I
Sbjct: 245 QYSSTIKKLQKLIQKGEIFQVVPSRKFFLPCN-NSLSAYQELKKSNPSPYMFFMQDEDFI 303
Query: 231 LVGASPETMGSVE--GRTVRINPIAGTAPRGKTPEE------DEEIRRRLLSDEKERAEH 282
L GASPE+ + R + + PIAGT PRG+ + D I + ++ KE AEH
Sbjct: 304 LFGASPESSLKYDEKNRQIELYPIAGTRPRGRKKDGTLDLDLDSRIELEMRTNHKELAEH 363
Query: 283 VMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFP 342
+MLVDLARND+ ++ +PGS + V KYSHV H+ S+V+G+L D A +
Sbjct: 364 LMLVDLARNDLARICEPGSRYVSDLVKVDKYSHVMHLVSKVVGQLKYGLDALHAYSSCMN 423
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
GTLTGAPK+RAM++I E E R YGGAIGYF+ G D I IR A +E A ++A
Sbjct: 424 MGTLTGAPKVRAMQLIAEYEGEGRGSYGGAIGYFTDLGNLDTCITIRSAYVESGVATIQA 483
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKA 429
GAG+V +SIPE E E+ NK +AV+ A
Sbjct: 484 GAGVVFNSIPEDEVKESLNKAQAVINA 510
>sp|P00898|TRPE_SALTY ANTHRANILATE SYNTHASE COMPONENT I >gi|47944|emb|CAA24668.1|
(V01378) trpE [Salmonella typhimurium]
Length = 520
Score = 194 bits (489), Expect = 1e-48
Identities = 122/277 (44%), Positives = 163/277 (58%), Gaps = 12/277 (4%)
Query: 164 IRTDANREE--FMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+R + N+ + F +V + ++ I AG++FQVV SR + L P+ Y L NPSPY
Sbjct: 234 MRCECNQSDDAFGAVVRQLQKAIRAGEIFQVVPSRRFSLPCP-SPLAAYYVLKKSNPSPY 292
Query: 222 TFILEFKKI-LVGASPETMGSVEG--RTVRINPIAGTAPRGK----TPEEDEEIRRRL-- 272
F ++ L GASPE+ + R + I PIAGT PRG+ T + D + R L
Sbjct: 293 MFFMQDNDFTLFGASPESSLKYDAASRQIEIYPIAGTRPRGRRADGTLDRDLDSRTELDM 352
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+D KE EH+MLVD ARND+ ++ PGS + V +YS V H+ S V+GEL D D
Sbjct: 353 RTDHKEPCEHLMLVDPARNDLARICTPGSRYVADLTKVDRYSCVIHLVSRVVGELRHDLD 412
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
A A GTL+GAPK+RAM++I + E RR YGGA+GYF+ G D I IR A
Sbjct: 413 ALHAYRACMNMGTLSGAPKVRAMQLIADAEGQRRGSYGGAVGYFTAHGDLDTCIVIRSAL 472
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+E A VRAGAGIV DS+P+ E ET NK +AVL+A
Sbjct: 473 VENGIATVRAGAGIVLDSVPQSEADETRNKARAVLRA 509
>pir||NNEB1T anthranilate synthase (EC 4.1.3.27) component I - Salmonella
typhimurium
Length = 520
Score = 194 bits (489), Expect = 1e-48
Identities = 122/277 (44%), Positives = 163/277 (58%), Gaps = 12/277 (4%)
Query: 164 IRTDANREE--FMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPY 221
+R + N+ + F +V + ++ I AG++FQVV SR + L P+ Y L NPSPY
Sbjct: 234 MRCECNQSDDAFGAVVRQLQKAIRAGEIFQVVPSRRFSLPCP-SPLAAYYVLKKSNPSPY 292
Query: 222 TFILEFKKI-LVGASPETMGSVEG--RTVRINPIAGTAPRGK----TPEEDEEIRRRL-- 272
F ++ L GASPE+ + R + I PIAGT PRG+ T + D + R L
Sbjct: 293 MFFMQDNDFTLFGASPESSLKYDAASRQIEIYPIAGTRPRGRRADGTLDRDLDSRTELDM 352
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+D KE EH+MLVD ARND+ ++ PGS + V +YS V H+ S V+GEL D D
Sbjct: 353 RTDHKEPCEHLMLVDPARNDLARICTPGSRYVADLTKVDRYSCVIHLVSRVVGELRHDLD 412
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE 392
A A GTL+GAPK+RAM++I + E RR YGGA+GYF+ G D I IR A
Sbjct: 413 ALHAYRACMNMGTLSGAPKVRAMQLIADAEGQRRGSYGGAVGYFTAHGDLDTCIVIRSAL 472
Query: 393 IEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+E A VRAGAGIV DS+P+ E ET NK +AVL+A
Sbjct: 473 VENGIATVRAGAGIVLDSVPQSEADETRNKARAVLRA 509
>sp|Q9ZES2|TRPE_BUCTC ANTHRANILATE SYNTHASE COMPONENT I >gi|4160152|emb|CAA09993.1|
(AJ012333) anthranilate synthase large subunit [Buchnera
aphidicola]
Length = 526
Score = 194 bits (489), Expect = 1e-48
Identities = 120/266 (45%), Positives = 159/266 (59%), Gaps = 11/266 (4%)
Query: 173 FMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-IL 231
+ V+K K+ I G+VFQ+V+SR++ L P+E Y L NPSPY F ++ + +L
Sbjct: 258 YKNKVKKMKQMILNGEVFQIVISRKFFLPCPY-PLESYIFLKKNNPSPYMFFMQDRHFVL 316
Query: 232 VGASPETMGSVEG--RTVRINPIAGTAPRGKTP------EEDEEIRRRLLSDEKERAEHV 283
GASPE+ R + I+PIAGT PR + ED ++ + + KE AEH
Sbjct: 317 FGASPESSLKFSSITRKIEIHPIAGTRPRAFSSIKKIDINEDNKMELAMRINSKELAEHC 376
Query: 284 MLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPA 343
MLVDLARND+ ++ PGS + V+KYSHV H+ S+V G L +D D+F A +
Sbjct: 377 MLVDLARNDLSRICLPGSRVVSDLMKVVKYSHVMHLVSKVEGVLRNDLDIFHAYQCCMNM 436
Query: 344 GTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAG 403
GTLTGAPKIRAM+II E E R YGGAIGYF+ G D I IR A + A V+AG
Sbjct: 437 GTLTGAPKIRAMQIIAE-EGEIRECYGGAIGYFTGKGDLDTCIVIRSAYVRNGIACVQAG 495
Query: 404 AGIVADSIPEKEFYETENKMKAVLKA 429
AGIV DSI ++E E +NK AV+ A
Sbjct: 496 AGIVLDSIADEENEECKNKAMAVINA 521
>pir||B82622 anthranilate synthase component I XF1914 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107012|gb|AAF84720.1|AE004011_5 (AE004011)
anthranilate synthase component I [Xylella fastidiosa]
Length = 498
Score = 193 bits (485), Expect = 4e-48
Identities = 107/283 (37%), Positives = 174/283 (60%), Gaps = 9/283 (3%)
Query: 152 EELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYR 211
E+++ +N E+I+ + R ++++ V K ++ GD++QV + ++ ++++ P+++YR
Sbjct: 206 EQVQDKNIDFEVIQ-ETTRHDYLDKVRKALHHVTVGDIYQVQIGQKIQVKAETTPLDVYR 264
Query: 212 KLISINPSPYTFILEFK-KILVGASPETMGSVE-GRTVRINPIAGTAPR--GKTPEEDEE 267
+L +NPSPY ++ + ++GASPE + + + PIAGT + G+T +
Sbjct: 265 RLRILNPSPYMYLFSINGQTVIGASPELFLRISTDEEILMRPIAGTLGKREGRTLHHATQ 324
Query: 268 IRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGEL 327
L +D KE AEH+MLVDL RND+ +V P S+K+ ++ +YSHV H+ S L
Sbjct: 325 ---HLQADNKEVAEHMMLVDLCRNDIYRVCTPESLKVSGVLEIEEYSHVYHMVSTTKAML 381
Query: 328 ADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSI-TGYADFAI 386
D +D + ASFPAGT+TGAPK+RAMEII ELE S+R Y GA+G I + Y + A+
Sbjct: 382 KQGLDKYDVMIASFPAGTMTGAPKVRAMEIISELEDSQRGKYAGALGILGIGSNYINTAL 441
Query: 387 AIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
IR ++ + +RA AGIV+DS + E+ ET +KM ++ KA
Sbjct: 442 CIRSTVLKNQVYTLRASAGIVSDSQEQSEYLETLHKMGSIFKA 484
>gb|AAF82314.1|L81122_1 (L81122) anthranilate synthase large subunit [Buchnera aphidicola]
Length = 519
Score = 192 bits (484), Expect = 5e-48
Identities = 115/273 (42%), Positives = 165/273 (60%), Gaps = 13/273 (4%)
Query: 166 TDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFIL 225
TDA +++ M+++ + +I GD+FQVV SR++ L + Y++L NPSPY F +
Sbjct: 244 TDA---QYLSMIKQLQIFIQKGDIFQVVPSRKFFLPCRY-ALSAYQELKKSNPSPYMFFM 299
Query: 226 EFKK-ILVGASPETMGSVE--GRTVRINPIAGTAPRGKTP------EEDEEIRRRLLSDE 276
+ + IL G SPE+ + R + + PIAGT RGK + D I + +++
Sbjct: 300 QDQAFILFGRSPESSLKYDEKNRQIELYPIAGTRSRGKNKNGSINYDLDSRIELEMRTNQ 359
Query: 277 KERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDA 336
KE +EH+MLVDLARND+ ++ +PGS + V KYSHV H+ S+VIG L + D+ A
Sbjct: 360 KELSEHLMLVDLARNDLARICEPGSRYVSELLKVDKYSHVMHLVSKVIGTLKSNLDVLHA 419
Query: 337 IEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGR 396
A GTLTGAPK+RAM++I + EK R YGGAIGY + G D I IR A +E
Sbjct: 420 YAACMNMGTLTGAPKVRAMQLIAKYEKETRGSYGGAIGYLTDAGNLDTCITIRSAYVEQN 479
Query: 397 KAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A V+AGAG+V +SI ++E E+ NK AV+ A
Sbjct: 480 IATVQAGAGVVLNSIAKEEVQESINKATAVINA 512
>sp|P12679|PABB_KLEAE PARA-AMINOBENZOATE SYNTHASE COMPONENT I (ADC SYNTHASE)
>gi|78990|pir||B31132 p-aminobenzoate synthase (EC
4.1.3.-) component I - Klebsiella pneumoniae
>gi|149291|gb|AAA88207.1| (M22078) p-aminobenzoate
synthase component I [Klebsiella aerogenes]
Length = 451
Score = 192 bits (483), Expect = 6e-48
Identities = 119/349 (34%), Positives = 182/349 (52%), Gaps = 10/349 (2%)
Query: 87 FLGGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPS 139
FLGG +G YD + + IE P + G Y W I +H + E+ + DP
Sbjct: 100 FLGGALGLFGYDLGRRFEHLPARADADIELPDMAVGIYDWALIVDHQRREVSLFSYDDPQ 159
Query: 140 FDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYV 199
+ + F A R + +REE+ E + + Y+ +GD +QV L++ +
Sbjct: 160 ARLAWLEAQTAPVAATFTLTSAW--RANMSREEYGEKFRQIQAYLHSGDCYQVNLAQRFT 217
Query: 200 LRSDVDPVELYRKLISINPSPYT-FILEFKKILVGASPETMGSVEGRTVRINPIAGTAPR 258
D + +R+L N +P++ FI + ++ SPE + ++ PI GT PR
Sbjct: 218 ATYRGDEWQAFRQLNRANRAPFSAFIRLDEGAVLSLSPERFIQLRQGDIQTRPIKGTLPR 277
Query: 259 GKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQH 318
PE+D +++L + K+RAE++M+VDL RND+ +V++PGSV++ F V + V H
Sbjct: 278 LADPEQDALQQQKLANSPKDRAENLMIVDLMRNDIGRVAEPGSVRVPELFVVEPFPAVHH 337
Query: 319 IESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSI 378
+ S V L D + A+FP G++TGAPK+RAMEIIDELE RR + G+IGY S
Sbjct: 338 LVSTVTARLPAHLHAADLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSF 397
Query: 379 TGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
G D +I IR + AG GIVADS E+ ET +K+ +L
Sbjct: 398 CGNMDSSITIRTLTAWQGHLYCSAGGGIVADSEEAAEYQETFDKVNRIL 446
>gb|AAF82318.1|L81124_1 (L81124) anthranilate synthase large subunit [Buchnera aphidicola]
Length = 521
Score = 190 bits (477), Expect = 3e-47
Identities = 115/275 (41%), Positives = 161/275 (57%), Gaps = 10/275 (3%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+ ++ + E+ ++ + +E+I GD+FQVV SR++ L S + Y+ L NPSPY F
Sbjct: 237 VTSNMSDAEYSSIITELQEFIQKGDIFQVVPSRKFFL-SCYHALSAYQALKISNPSPYMF 295
Query: 224 ILEFKKI-LVGASPETMGSVEG--RTVRINPIAGTAPRGKTPEE------DEEIRRRLLS 274
++ + L GASPE+ R V + PIAGT PRGK + D I + +
Sbjct: 296 FMQDQLFTLFGASPESSLKYNRITRQVELYPIAGTRPRGKRTDGSIDYDLDSRIELEMRT 355
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
++KE +EH+M VDLARND+ ++ +PGS + V KYSHV H+ S+VIG L D
Sbjct: 356 NQKELSEHLMHVDLARNDLARICEPGSRYVSELVKVDKYSHVMHLVSKVIGTLKSHLDAL 415
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A + GTLTGAPK+RAME+I EK R YGGAIGYF+ G D I IR A IE
Sbjct: 416 HAYASCMNMGTLTGAPKVRAMELIAACEKETRGSYGGAIGYFTDEGNLDTCITIRSAYIE 475
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
A V++GAG+V +S ++E E+ NK AV+ A
Sbjct: 476 KDMATVQSGAGVVLNSTAQEEVTESVNKAAAVINA 510
>sp|P27630|PABB_STRLI PARA-AMINOBENZOATE SYNTHASE COMPONENT I (ADC SYNTHASE)
>gi|541500|pir||JN0578 p-Aminobenzoic acid synthetase
(EC 4.1.3.-) B - Streptomyces lividans
>gi|153394|gb|AAA26798.1| (M64859) putative
[Streptomyces lividans]
Length = 475
Score = 188 bits (473), Expect = 9e-47
Identities = 122/360 (33%), Positives = 189/360 (51%), Gaps = 17/360 (4%)
Query: 87 FLGGFMGYIAYD------AVHNYIEGSIEEPSVFGYYPWVFIYNHGKGELRFYYL----- 135
F GG +G AYD A+ + + + P + +Y+H +
Sbjct: 107 FQGGALGRFAYDIARRLEAIRDLGDRELAGPDAGTALYDLILYDHQDDVIWILVPNEAGE 166
Query: 136 RDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLS 195
+DPS D +V ++ +F+ G + + + + V++ K+Y+ +GD++QV L+
Sbjct: 167 QDPSEDFRDLVNAWSYDD-EFDIGAE--FGANYTDDAYADGVDRLKDYLGSGDMYQVNLA 223
Query: 196 REYVLRSDVDPVELYRKLISINPSPYTFILEFKKILVGASPETMGSVEGRTVRINPIAGT 255
+ V + +LY +L NP+PY L+ + L+ ASPE + E + PIAGT
Sbjct: 224 QRRVGMISAEDYQLYIRLRDANPAPYMAYLDIDEGLLVASPERIILDEASDLDTRPIAGT 283
Query: 256 A---PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIK 312
PR +ED+ LL +K+RAE +M+VDL RND+ +V GSVK+ + +
Sbjct: 284 LRGRPRAGGDDEDDGRAIDLLRVDKDRAERIMIVDLDRNDIARVGVGGSVKVREIMGLER 343
Query: 313 YSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGA 372
YS V H+ S+V G+L + + D I A FP GTLTGAPK+R MEIIDELE RR Y G+
Sbjct: 344 YSGVMHLVSQVTGDLQEAIEAVDLIRAGFPGGTLTGAPKVRTMEIIDELEPQRRAAYCGS 403
Query: 373 IGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
IGY + G DF IAI + +AG G+V DS+P+ E+ E+ K A+++ +
Sbjct: 404 IGYIAYKGNIDFKIAIPTLYALAGQLFCQAGGGVVGDSVPDGEYRESFEKGNALIRGLEI 463
>sp|P05041|PABB_ECOLI PARA-AMINOBENZOATE SYNTHASE COMPONENT I (ADC SYNTHASE)
>gi|68257|pir||AGEC1 p-aminobenzoate synthase (EC
4.1.3.-) component I - Escherichia coli
>gi|147058|gb|AAA24266.1| (K02673) p-aminobenzoate
synthetase [Escherichia coli]
>gi|1736449|dbj|BAA15619.1| (D90825) p-aminobenzoate
synthase (EC 4.1.3.-) component I [Escherichia coli]
>gi|1788114|gb|AAC74882.1| (AE000275) p-aminobenzoate
synthetase, component I [Escherichia coli K12]
Length = 453
Score = 187 bits (470), Expect = 2e-46
Identities = 129/416 (31%), Positives = 203/416 (48%), Gaps = 26/416 (6%)
Query: 33 DSKEAKLTYISASPEFTVEISGKGTFL-DGKKVSNETNPFLSLKSFNMDSAS-------G 84
D ++ + A P T+ GK T + + +K + T+ L + +D A
Sbjct: 40 DHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNED 99
Query: 85 SGFLGGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRD 137
F GG +G YD + E I P + G Y W I +H + + D
Sbjct: 100 LPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHND 159
Query: 138 PSFDPETIVERAKREELKFENGGAEIIRTD----ANREEFMEMVEKGKEYIFAGDVFQVV 193
+ RA E +F + +D RE++ E + +EY+ +GD +QV
Sbjct: 160 VN------ARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVN 213
Query: 194 LSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPI 252
L++ + D + + +L N +P++ L ++ ++ SPE + ++ PI
Sbjct: 214 LAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPI 273
Query: 253 AGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIK 312
GT PR P+ED + +L + K+RAE++M+VDL RND+ +V+ GSVK+ F V
Sbjct: 274 KGTLPRLPDPQEDSKQAVKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEP 333
Query: 313 YSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGA 372
+ V H+ S + +L + D + A+FP G++TGAPK+RAMEIIDELE RR + G+
Sbjct: 334 FPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGS 393
Query: 373 IGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLK 428
IGY S G D +I IR + AG GIVADS E E+ ET +K+ +LK
Sbjct: 394 IGYLSFCGNMDTSITIRTLTAINGQIFCSAGGGIVADSQEEAEYQETFDKVNRILK 449
>sp|P12680|PABB_SALTY PARA-AMINOBENZOATE SYNTHASE COMPONENT I (ADC SYNTHASE)
>gi|79107|pir||A31132 p-aminobenzoate synthase (EC
4.1.3.-) component I - Salmonella typhimurium
>gi|154231|gb|AAA88618.1| (M22079) p-aminobenzoate
synthase component I [Salmonella typhimurium]
Length = 454
Score = 185 bits (466), Expect = 6e-46
Identities = 114/349 (32%), Positives = 175/349 (49%), Gaps = 10/349 (2%)
Query: 87 FLGGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPS 139
F GG +G YD + I P + G Y W I +H K + D
Sbjct: 103 FQGGALGLFGYDLGRRFEILPDTAARDIALPDMAIGLYDWALIVDHQKQVVSLISYHDAD 162
Query: 140 FDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYV 199
+ + F A +++ R E+ E + + ++ +GD +QV LS+ +
Sbjct: 163 ARYRWLTSQRAPTRTPFRLTSAW--QSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQRFQ 220
Query: 200 LRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTAPR 258
+ D + + +L N +P++ L ++ SPE +E ++ PI GT PR
Sbjct: 221 ASYEGDEWQAFERLNRANRAPFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKGTLPR 280
Query: 259 GKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQH 318
P+ D + ++L + K+RAE++M+VDL RND+ +V+ PGSVK+ F V + V H
Sbjct: 281 LNDPQADRQQAQKLANSMKDRAENLMIVDLMRNDIGRVAVPGSVKVPELFVVEPFPAVHH 340
Query: 319 IESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSI 378
+ S + L D D + A+FP G++TGAPK+RAMEIIDELE RR + G+IGY S
Sbjct: 341 LVSTITARLPDSLHATDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSF 400
Query: 379 TGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
G D +I IR + + AG GIVADS E E+ ET +K+ +L
Sbjct: 401 CGKMDTSITIRTVTATQGQLYCSAGGGIVADSNEEAEYQETFDKVNRIL 449
>sp|P15395|TRPE_RHIME ANTHRANILATE SYNTHASE [INCLUDES: GLUTAMINE AMIDOTRANSFERASE]
>gi|95177|pir||A30904 anthranilate synthase (EC
4.1.3.27) - Rhizobium meliloti >gi|152445|gb|AAA26370.1|
(M22983) anthranilate synthase (trpE(G)) (EC 4.1.3.27)
[Sinorhizobium meliloti]
Length = 729
Score = 181 bits (455), Expect = 1e-44
Identities = 106/260 (40%), Positives = 148/260 (56%), Gaps = 2/260 (0%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEF--KK 229
E+ E+V K KE GD+F+VV +++ R + P E+ +L +INPSPY+F + ++
Sbjct: 247 EYAELVVKAKESFRRGDLFEVVPGQKFYERCESRPSEISNRLKAINPSPYSFFINLGNQE 306
Query: 230 ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLA 289
LVGASPE V GR + PI+GT RG P D E +LL+ +K+ +E M D+
Sbjct: 307 YLVGASPEMFVRVSGRRIETCPISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVD 366
Query: 290 RNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGA 349
RND +V PGSVK++ + YS + H + G L DD D FD + A T+TGA
Sbjct: 367 RNDKSRVCVPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDDMDAFDGFLSHAWAVTVTGA 426
Query: 350 PKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVAD 409
PK+ AM I+ EKS R YGGAIG G + + +R I+ A VRAGA ++ D
Sbjct: 427 PKLWAMRFIESHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLYD 486
Query: 410 SIPEKEFYETENKMKAVLKA 429
S PE+E ETE K A++ A
Sbjct: 487 SNPEEEEAETELKASAMIAA 506
>sp|P32483|PABS_STRGR PARA-AMINOBENZOATE SYNTHASE (P-AMINOBENZOIC ACID SYNTHASE) (PABA
SYNTHASE) >gi|484360|pir||JN0531 p-aminobenzoic acid
synthase (EC 4.1.3.-) - Streptomyces griseus
>gi|388263|gb|AAA72111.1| (M93058) p-aminobenzoic acid
synthase [Streptomyces griseus]
Length = 723
Score = 181 bits (454), Expect = 2e-44
Identities = 101/263 (38%), Positives = 155/263 (58%), Gaps = 4/263 (1%)
Query: 169 NREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFK 228
+R+ ++++++ ++ I AG+ ++V L+ +D+ P YR L ++P+P+ L+F
Sbjct: 426 DRDGYLKLIDVCQQEIAAGETYEVCLTNMAEADTDLTPWAAYRALRRVSPAPFAAFLDFG 485
Query: 229 KILV-GASPETMGSVE--GRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVML 285
+ V +SPE ++ GR + PI GT PRG TP+ED + R L + EK+RAE++M+
Sbjct: 486 PMAVLSSSPERFLRIDRHGR-MESKPIKGTRPRGATPQEDAALVRALATCEKDRAENLMI 544
Query: 286 VDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGT 345
VDL R+D+ + ++ GSV F V Y+ V + S V L +D A+ A+FP G+
Sbjct: 545 VDLVRHDLGRCAEVGSVVADPVFQVETYATVHQLVSTVTARLREDSSPVAAVRAAFPGGS 604
Query: 346 LTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAG 405
+TGAPKIR M+IID LE R VY GAIGYFS+TG D +I IR + G + G
Sbjct: 605 MTGAPKIRTMQIIDRLEGGPRGVYSGAIGYFSLTGAVDLSIVIRTVVLSGGRLRYGVGGA 664
Query: 406 IVADSIPEKEFYETENKMKAVLK 428
++A S P EF ET K +L+
Sbjct: 665 VIALSDPADEFEETAVKAAPLLR 687
>pir||B82216 para-aminobenzoate synthase, component I VC1303 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655792|gb|AAF94462.1| (AE004210) para-aminobenzoate
synthase, component I [Vibrio cholerae]
Length = 458
Score = 180 bits (452), Expect = 3e-44
Identities = 110/359 (30%), Positives = 183/359 (50%), Gaps = 28/359 (7%)
Query: 87 FLGGFMGYIAYD------AVHNYIEGSIEEPSV-FGYYPWVFIYNHGKGELRF------- 132
F+GG +GY +YD + + E I P + G Y W + +H + +
Sbjct: 105 FVGGALGYFSYDLGRRVEVLPSLAEQDIAMPDMAVGIYSWALVVDHQQHTAQLVGQNVED 164
Query: 133 ---YYLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDV 189
+ + + P + + A R++ + + + + ++Y+ +GD
Sbjct: 165 AWGWLNQQEAIKPSEVTDFALTSPW----------RSNMSYTAYQDKFARVQDYLRSGDC 214
Query: 190 FQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVR 248
+Q+ L++ + + Y KL N +P++ L + ++ SPE V R +
Sbjct: 215 YQINLAQRFQAHYTGSEWQAYLKLEKGNQAPFSAFLRLPQGAILSVSPERFLQVCDRVIE 274
Query: 249 INPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFF 308
PI GT PR ++D +++ L+S EK++AE++M+VDL RND+ +V+KPGSV + + F
Sbjct: 275 TKPIKGTRPRHADKQQDALLKQDLVSAEKDQAENLMIVDLLRNDIGRVAKPGSVHVPKLF 334
Query: 309 DVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRV 368
DV + V H+ S + L + D + A FP G++TGAPK+RAMEII+ELE RR
Sbjct: 335 DVESFPAVHHLVSTIRATLDEQYQAADLLRACFPGGSITGAPKVRAMEIIEELEPHRRSA 394
Query: 369 YGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
Y G+IGY S G D +I IR ++ + AG G+VADS E+ ET +K+ +L
Sbjct: 395 YCGSIGYLSRHGKMDTSITIRTLVAYQQQLYAWAGGGLVADSEGAAEYQETLDKLSRIL 453
>sp|O25869|TRPE_HELPY ANTHRANILATE SYNTHASE COMPONENT I >gi|7436739|pir||B64680
anthranilate synthase component I - Helicobacter pylori
(strain 26695) >gi|2314448|gb|AAD08326.1| (AE000632)
anthranilate synthase component I (trpE) [Helicobacter
pylori 26695]
Length = 500
Score = 179 bits (449), Expect = 6e-44
Identities = 112/275 (40%), Positives = 155/275 (55%), Gaps = 12/275 (4%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+ + + EF + V +E I G++FQ VLSR + + ++ + Y L NPSPY F
Sbjct: 223 VSANCSDSEFEKRVLSLQEEIKKGEIFQAVLSRSFYMEC-LEGLSAYYHLKLTNPSPYMF 281
Query: 224 ILEFKK-ILVGASPETMGSVEG--RTVRINPIAGTAPRGKTPEE------DEEIRRRLLS 274
++ IL GASPE+ T I PIAGT RGK + D ++ L
Sbjct: 282 YIKDSDFILFGASPESALKYNALTNTAEIYPIAGTRLRGKDKQGNIDYDLDSKMEFDLQH 341
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
D KERAEH+MLVDLARND+ +VSK + V KYS+V H+ S V+GEL D
Sbjct: 342 DYKERAEHIMLVDLARNDMARVSKKRYCD--KLLKVDKYSNVMHLVSRVVGELKKGCDSL 399
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A + AGTL+GAPKI A+ +I +LE RR YGG++GY + G D I IR ++
Sbjct: 400 HAYRSFMNAGTLSGAPKISAIRLIYQLENQRRGSYGGSVGYLNSEGSMDSCITIRSCFVK 459
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+A ++AGAGIV DS+P+ E ET K +A++ A
Sbjct: 460 NNRAVIQAGAGIVLDSVPQNEANETRAKAQALIDA 494
>sp|P06557|TRPE_BRELA ANTHRANILATE SYNTHASE COMPONENT I >gi|39593|emb|CAA28623.1|
(X04960) trpE (AA 1-518) [Corynebacterium glutamicum]
>gi|40523|emb|CAA39467.1| (X55994) anthranilate synthase
component 1 [Corynebacterium glutamicum]
Length = 518
Score = 178 bits (448), Expect = 8e-44
Identities = 113/274 (41%), Positives = 154/274 (55%), Gaps = 14/274 (5%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
+F + + KE I+ GD++QVV +R + D Y +L + NPSPY F +
Sbjct: 236 QFRTQINELKENIYNGDIYQVVPARTFTAPCP-DAFAAYLQLRATNPSPYMFYIRGLNEG 294
Query: 231 ----LVGASPET--MGSVEGRTVRINPIAGTAPRGKTPE----EDEEIRRRL--LSDEKE 278
L GASPE+ + R +++ PIAGT PRG P+ ++ +IR L +D KE
Sbjct: 295 RSYELFGASPESNLKFTAANRELQLYPIAGTRPRGLNPDGSINDELDIRNELDMRTDAKE 354
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
A+ MLVDLARND+ +VS P S ++ V +YS V H+ S V L + D DA
Sbjct: 355 IADDTMLVDLARNDLARVSVPASRRVADLLQVDRYSRVMHLVSRVTATLDPELDALDAYR 414
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
A GTLTGAPK+RAME++ +EK RR YGGA+GY G D I IR A ++ A
Sbjct: 415 ACMNMGTLTGAPKLRAMELLRGVEKRRRGSYGGAVGYLRGNGDMDNCIVIRSAFVQDGVA 474
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
V+AGAG+V DS P+ E ET +K AVL A +
Sbjct: 475 AVQAGAGVVRDSNPQSEADETLHKAYAVLNAIAL 508
>pir||B24723 anthranilate synthase (EC 4.1.3.27) component 1 - Corynebacterium
glutamicum
Length = 518
Score = 178 bits (448), Expect = 8e-44
Identities = 113/274 (41%), Positives = 154/274 (55%), Gaps = 14/274 (5%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
+F + + KE I+ GD++QVV +R + D Y +L + NPSPY F +
Sbjct: 236 QFRTQINELKENIYNGDIYQVVPARTFTAPCP-DAFAAYLQLRATNPSPYMFYIRGLNEG 294
Query: 231 ----LVGASPET--MGSVEGRTVRINPIAGTAPRGKTPE----EDEEIRRRL--LSDEKE 278
L GASPE+ + R +++ PIAGT PRG P+ ++ +IR L +D KE
Sbjct: 295 RSYELFGASPESNLKFTAANRELQLYPIAGTRPRGLNPDGSINDELDIRNELDMRTDAKE 354
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
A+ MLVDLARND+ +VS P S ++ V +YS V H+ S V L + D DA
Sbjct: 355 IADDTMLVDLARNDLARVSVPASRRVADLLQVDRYSRVMHLVSRVTATLDPELDALDAYR 414
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
A GTLTGAPK+RAME++ +EK RR YGGA+GY G D I IR A ++ A
Sbjct: 415 ACMNMGTLTGAPKLRAMELLRGVEKRRRGSYGGAVGYLRGNGDMDNCIVIRSAFVQDGVA 474
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
V+AGAG+V DS P+ E ET +K AVL A +
Sbjct: 475 AVQAGAGVVRDSNPQSEADETLHKAYAVLNAIAL 508
>pir||B48967 anthranilate synthase (EC 4.1.3.27) component I - Corynebacterium
glutamicum >gi|299879|gb|AAB26396.1| trpE product
[Corynebacterium glutamicum, ATCC 21850, Peptide, 518
aa]
Length = 518
Score = 178 bits (447), Expect = 1e-43
Identities = 113/274 (41%), Positives = 154/274 (55%), Gaps = 14/274 (5%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI- 230
+F + + KE I+ GD++QVV +R + D Y +L + NPSPY F +
Sbjct: 236 QFRTQINELKENIYNGDIYQVVPARTFTAPCP-DAFAAYLQLRATNPSPYMFYIRGLNEG 294
Query: 231 ----LVGASPET--MGSVEGRTVRINPIAGTAPRGKTPE----EDEEIRRRL--LSDEKE 278
L GASPE+ + R +++ PIAGT PRG P+ ++ +IR L +D KE
Sbjct: 295 RSYELPGASPESNLKFTAANRELQLYPIAGTRPRGLNPDGSINDELDIRNELDMRTDAKE 354
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIE 338
A+ MLVDLARND+ +VS P S ++ V +YS V H+ S V L + D DA
Sbjct: 355 IADDTMLVDLARNDLARVSVPASRRVADLLQVDRYSRVMHLVSRVTATLDPELDALDAYR 414
Query: 339 ASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKA 398
A GTLTGAPK+RAME++ +EK RR YGGA+GY G D I IR A ++ A
Sbjct: 415 ACMNMGTLTGAPKLRAMELLRGVEKRRRGSYGGAVGYLRGNGDMDNCIVIRSAFVQDGVA 474
Query: 399 HVRAGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
V+AGAG+V DS P+ E ET +K AVL A +
Sbjct: 475 AVQAGAGVVRDSNPQSEADETLHKAYAVLNAIAL 508
>sp|Q9ZJU5|TRPE_HELPJ ANTHRANILATE SYNTHASE COMPONENT I >gi|7436738|pir||G71836
anthranilate synthase component I - Helicobacter pylori
(strain J99) >gi|4155807|gb|AAD06782.1| (AE001546)
ANTHRANILATE SYNTHASE COMPONENT I [Helicobacter pylori
J99]
Length = 500
Score = 178 bits (447), Expect = 1e-43
Identities = 112/275 (40%), Positives = 156/275 (56%), Gaps = 12/275 (4%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTF 223
+ + EF + V +E I G++FQ VLSR + + ++ + Y L NPSPY F
Sbjct: 223 VSVSCDDSEFEKKVLFLQEEIKKGEIFQAVLSRSFYMEC-LEGLSAYYHLKLSNPSPYMF 281
Query: 224 ILEFKK-ILVGASPETMGSVEG--RTVRINPIAGTAPRGKTPEE------DEEIRRRLLS 274
++ IL GASPE+ T I PIAGT RGK + D ++ L
Sbjct: 282 YIKDSDFILFGASPESALKYNALTNTAEIYPIAGTRLRGKDKQGNIDYDLDSKMEFDLQH 341
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
D KERAEH+MLVDLARND+ +VSK + V KYS+V H+ S V+GEL D
Sbjct: 342 DYKERAEHIMLVDLARNDMARVSKKRYCD--KLLKVDKYSNVMHLVSRVVGELKKGCDSL 399
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A + AGTL+GAPKI A+++I +LE RR YGG++GY + G D I IR ++
Sbjct: 400 HAYRSFMNAGTLSGAPKISAIKLIYQLENQRRGSYGGSVGYLNSEGSMDSCITIRSCFVK 459
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKA 429
+A ++AGAGIV DS+P+ E ET K++A++ A
Sbjct: 460 NNRAVIQAGAGIVLDSVPQNEANETRAKVQALIDA 494
>gb|AAC79592.1| (AC005727) putative para-aminobenzoate synthase and glutamine
amidotransferase, a bifunctional enzyme [Arabidopsis
thaliana]
Length = 917
Score = 175 bits (438), Expect = 1e-42
Identities = 103/268 (38%), Positives = 151/268 (55%), Gaps = 5/268 (1%)
Query: 167 DANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLR-SDVDPVELYRKLISINPSPYTFIL 225
D +RE+++ V+ +YI G+ +++ L+ + + + DP+ LY L NP+PY L
Sbjct: 639 DKSREQYINDVQSCMKYIKDGESYELCLTTQNRRKIGNADPLGLYLHLRERNPAPYAAFL 698
Query: 226 EFKKI---LVGASPETMGSVEGR-TVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAE 281
F L +SPE ++ + PI GT RG TPEEDE ++ +L EK +AE
Sbjct: 699 NFSNANLSLCSSSPERFLKLDRNGMLEAKPIKGTIARGSTPEEDEFLKLQLKLSEKNQAE 758
Query: 282 HVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF 341
++M+VDL RND+ +V +PGSV + DV Y+ V + S + G D + + A+F
Sbjct: 759 NLMIVDLLRNDLGRVCEPGSVHVPNLMDVESYTTVHTMVSTIRGLKKTDISPVECVRAAF 818
Query: 342 PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVR 401
P G++TGAPK+R++EI+D LE R +Y G+IGYFS G D I IR I +A +
Sbjct: 819 PGGSMTGAPKLRSVEILDSLENCSRGLYSGSIGYFSYNGTFDLNIVIRTVIIHEDEASIG 878
Query: 402 AGAGIVADSIPEKEFYETENKMKAVLKA 429
AG IVA S PE EF E K +A A
Sbjct: 879 AGGAIVALSSPEDEFEEMILKTRAPANA 906
>sp|P27629|PABB_LACLA PARA-AMINOBENZOATE SYNTHASE COMPONENT I (ADC SYNTHASE)
>gi|149462|gb|AAA17025.1| (M64860) p-aminobenzoic acid
synthetase [Lactococcus lactis]
Length = 470
Score = 170 bits (427), Expect = 2e-41
Identities = 120/363 (33%), Positives = 181/363 (49%), Gaps = 20/363 (5%)
Query: 86 GFLGGFMGYIAYDA---VHNYIEGSIEE---PSVFGYYPWVFIYNHGKGELRFYYLRDPS 139
GF GG +GY AYD + Y + IE+ P + G + + + ++ + S
Sbjct: 97 GFQGGALGYFAYDVGRRLEGYNDLGIEDWAIPDLAGSSYEIGVSADHQNDV-IVLIAHAS 155
Query: 140 FDPETIVERAKREELKFE------NGGAEIIRTDANREEFMEMVEKG------KEYIFAG 187
D + + R+ +G EI+R + + + K+Y+ +G
Sbjct: 156 ADGNDVFITSSRQLSMVAGPTCCASGDVEILRNKLHYYGVIPFSQDDCGFNRLKDYLGSG 215
Query: 188 DVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKILVGASPETMGSVEGRTV 247
D++QV L V + + Y +L +NP PY L+ I++ ASPE + + E +
Sbjct: 216 DMYQVNLGNRNVGAIVMTLFQGYNQLRLMNPGPYMVFLDEANIIM-ASPEIVLADEANDL 274
Query: 248 RINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRF 307
PIAGT R +ED L K+RAEH+M+VDL RND+ +V + GSV +
Sbjct: 275 NTRPIAGTLMRLNEQDEDGVNAACLGQHHKDRAEHMMIVDLVRNDLGRVGRFGSVNVQEI 334
Query: 308 FDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRR 367
YS V HI S V G L + + + I A FP G++TGAPK+RAMEII+ELE RR
Sbjct: 335 VGAENYSVVMHIVSRVTGSLNEAFEAMEIIRAGFPGGSITGAPKVRAMEIIEELEPQRRD 394
Query: 368 VYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
+GG+IGY + G + IAIR + +GAG+V DS+ + E+ ET KM+A+
Sbjct: 395 GWGGSIGYIAYRGNIGYRIAIRTLFACNGQLFASSGAGLVGDSMEDGEYNETFEKMRALR 454
Query: 428 KAF 430
F
Sbjct: 455 SFF 457
>pir||F75547 anthranilate synthase component I - Deinococcus radiodurans
(strain R1) >gi|6457866|gb|AAF09783.1|AE001882_1
(AE001882) anthranilate synthase component I
[Deinococcus radiodurans]
Length = 638
Score = 162 bits (406), Expect = 7e-39
Identities = 125/364 (34%), Positives = 176/364 (48%), Gaps = 35/364 (9%)
Query: 87 FLGGFMGYIAYDAVHNYIEGSIEEPSV-----FGYYPWVFIYNHGKGELRFYYLRDPSFD 141
F ++G + Y+A + G P+ +G+YP +++ G L + +P D
Sbjct: 57 FFPAWLGGLKYEAAREF--GLAAHPASGPAQWWGFYPSGLVWDREAGTLSV--VGEPHLD 112
Query: 142 PETIV--ERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYV 199
++ + A L + GA+ + A V +E I AG+V+QV LSR
Sbjct: 113 WAALLASDPAPLPSLTVGDFGADDVDYPAG-------VRAVQELIRAGEVYQVNLSRGVS 165
Query: 200 LRSDVDPVELYRKLISINPSPYTFILEF-KKILVGASPETM---GSVEGRTVRINPIAGT 255
+ DP+ Y +L +NPSP+ L+ +++V SPE + EG + PIAGT
Sbjct: 166 APAQGDPLAAYLRLREVNPSPFMAFLDMGNEVVVSCSPERLVDWAVSEGGGISARPIAGT 225
Query: 256 APRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSH 315
RG TPEED L + KE AEH MLVDL R+D+ V+ PG+V + V +YSH
Sbjct: 226 RRRGDTPEEDAAFEAELRASPKEVAEHTMLVDLVRHDLGAVAAPGTVSVPDLMLVERYSH 285
Query: 316 VQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGY 375
V H+ SEV + D + A+FP GT+TGAPK R M+ I LE R Y G G
Sbjct: 286 VMHLVSEVTATARAGLTLPDLLAATFPGGTITGAPKARVMDAIAALEPGPRGWYTGGAGL 345
Query: 376 FSITGYADFAIAIRMAEI-----EGRKA-------HVRAGAGIVADSIPEKEFYETENKM 423
S D I IR AE G A VRAG G V D+ P +E ET +K
Sbjct: 346 VS-GRRVDVNILIRTAEFVLDTAAGSPATPPRWTVTVRAGGGTVIDADPAREARETVHKA 404
Query: 424 KAVL 427
+A+L
Sbjct: 405 QALL 408
>emb|CAC11935.1| (AL445065) anthranilate synthase component I related protein
[Thermoplasma acidophilum]
Length = 356
Score = 156 bits (391), Expect = 4e-37
Identities = 103/293 (35%), Positives = 168/293 (57%), Gaps = 22/293 (7%)
Query: 139 SFDPETIVER--AKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSR 196
SFDP+T+++R + L + G D + + + + ++ I +G+V Q V+SR
Sbjct: 82 SFDPDTVMKRRIVRSGYLTRKEVG------DFSDPDLSRKIAEVRDLIRSGEVLQAVISR 135
Query: 197 EYVLRSDVDPVELYRKLISINPSPYTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGT 255
++ + +DP E R+ I + S Y F K +VG+SPE + +V G V +PIAGT
Sbjct: 136 DF--EACIDPWEKLREFIDHDRSRYVFYYRIGKYQVVGSSPENLVTVSGNEVFTDPIAGT 193
Query: 256 APRGKTPEEDEEIRRR-LLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYS 314
P +R LL K+ EH ML+DLARND+ K + G++ + + + ++S
Sbjct: 194 VP--------STVRSSVLLESMKDANEHRMLLDLARNDLSKFADIGTLGVSKVMQIEEFS 245
Query: 315 HVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIG 374
V+H+ S+V ++ + D +++ FPAGT++G+PK RA+EII++ E++ R YGG+IG
Sbjct: 246 SVKHLVSQVRASFSNTPYL-DILKSMFPAGTVSGSPKERAIEIIEKYEETPRGPYGGSIG 304
Query: 375 YFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVL 427
++ G D A+ IR A +G VRAGAGIV DS P+ E E +K ++V+
Sbjct: 305 -ITMDGMMDLALTIRSAYSDGSGFRVRAGAGIVKDSDPDAEVREIYSKARSVI 356
>pir||F70398 p-aminobenzoate synthetase - Aquifex aeolicus
>gi|2983603|gb|AAC07173.1| (AE000725) p-aminobenzoate
synthetase [Aquifex aeolicus]
Length = 348
Score = 152 bits (379), Expect = 1e-35
Identities = 93/264 (35%), Positives = 141/264 (53%), Gaps = 13/264 (4%)
Query: 171 EEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKKI 230
EE+ E ++K K+YI GDV+Q+ L+ + EL+ P P+ F LE +
Sbjct: 94 EEYKERIKKIKKYIEKGDVYQINLTNRFEFELKGSSEELFFNFYEAQPVPFAFYLELEDF 153
Query: 231 -LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLA 289
++ S E +G +R PI GTA KT LL EKERAE++M+ D+
Sbjct: 154 YVISGSMELFLEKKGNVIRSKPIKGTAKEEKT----------LLLSEKERAENLMITDMM 203
Query: 290 RNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGA 349
RND+ ++++ GSV++ F V KY + H+ S V G DK + + + ++FP ++TGA
Sbjct: 204 RNDIGRIARTGSVEVEELFKVEKYRTLYHMHSTVKG--ITDKSLSEILSSTFPPASVTGA 261
Query: 350 PKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVAD 409
PK RA+EIIDELE R Y G+ G ++ IR A G + + AG GIV D
Sbjct: 262 PKRRAVEIIDELEPFSRSYYCGSGGLVFSEEDFTLSVLIRTAIGRGDRLYYYAGCGIVWD 321
Query: 410 SIPEKEFYETENKMKAVLKAFGVI 433
S+ E+E E K++A +A ++
Sbjct: 322 SVEERETEEMHLKVEAFKRAGSLV 345
>pir||T17434 anthranilate synthase component I ybtS [similarity] - Yersinia
pestis >gi|3818599|gb|AAC69582.1| (AF091251) YbtS
[Yersinia pestis] >gi|4106630|emb|CAA21385.1| (AL031866)
ORF62, len=434 aa, salicylate synthase, similar to
anthranilate synthase component TrpE2, eg. MTCY253_2
Mycobacterium tuberculosis H37Rv (450 aa), 37.1%
identity in 420 aa overlap, Fasta scores: opt: 896,
E(): 0 [Yersinia pestis]
Length = 434
Score = 141 bits (353), Expect = 1e-32
Identities = 91/265 (34%), Positives = 141/265 (52%), Gaps = 4/265 (1%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVD--PVELYRKLISINPSPY 221
+ T N E + + V + I G+ +V++SR L S +D LY + + +
Sbjct: 166 VDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSF 225
Query: 222 TFILEFKKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAE 281
F E ++ L G SPE + SV G V P+AGT R PE ++ LL D KE E
Sbjct: 226 MFRQEGREAL-GFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLE 284
Query: 282 HVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF 341
H++ V A ++ V +PGSV + V + VQH+ S V G+LA++KD +DA F
Sbjct: 285 HILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLF 344
Query: 342 PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVR 401
P+ T +G PK A+ I ++EK+ R +Y GAI T + D A+ +R + ++ ++
Sbjct: 345 PSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRF-DAALVLRSVFQDSQRCWIQ 403
Query: 402 AGAGIVADSIPEKEFYETENKMKAV 426
AGAGI+A S PE+E ET K+ ++
Sbjct: 404 AGAGIIAQSTPERELTETREKLASI 428
>gb|AAD17661.1| (AF069749) unknown [Yersinia pestis]
Length = 434
Score = 141 bits (353), Expect = 1e-32
Identities = 91/265 (34%), Positives = 141/265 (52%), Gaps = 4/265 (1%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVD--PVELYRKLISINPSPY 221
+ T N E + + V + I G+ +V++SR L S +D LY + + +
Sbjct: 166 VDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSF 225
Query: 222 TFILEFKKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAE 281
F E ++ L G SPE + SV G V P+AGT R PE ++ LL D KE E
Sbjct: 226 MFRQEGREAL-GFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLE 284
Query: 282 HVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF 341
H++ V A ++ V +PGSV + V + VQH+ S V G+LA++KD +DA F
Sbjct: 285 HILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLF 344
Query: 342 PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVR 401
P+ T +G PK A+ I ++EK+ R +Y GAI T + D A+ +R + ++ ++
Sbjct: 345 PSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRF-DAALVLRSVFQDSQRCWIQ 403
Query: 402 AGAGIVADSIPEKEFYETENKMKAV 426
AGAGI+A S PE+E ET K+ ++
Sbjct: 404 AGAGIIAQSTPERELTETREKLASI 428
>pir||S27508 hypothetical protein 2 - Bacillus subtilis
>gi|557488|gb|AAA50397.1| (M74521) Unknown [Bacillus
subtilis]
Length = 321
Score = 141 bits (352), Expect = 1e-32
Identities = 97/307 (31%), Positives = 154/307 (49%), Gaps = 24/307 (7%)
Query: 141 DPETIVERAKR-------EELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVV 193
D E ++E K + K E+ + +++++++ +E I +VV
Sbjct: 19 DAEAVLEGLKAFAAEFMVPDFKQEDQAVIAAAEELDKDDWLKAIETATSQIKEKQYDKVV 78
Query: 194 LSREYVLRSD----VDPVELYRKLISINPSPYTFILEFK-KILVGASPETMGSVEGRTVR 248
L+RE +L D ++PV + L+ + Y F +E + K VGASPE + +G TV
Sbjct: 79 LARELLLTFDGPIQIEPV--LKTLLDDQQTSYVFAIEQEGKTFVGASPERLIKRDGGTVM 136
Query: 249 INPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARN----DVRKVSKPGSVKL 304
+ +AG+ RG E+D I LL+DEK EH ++V + N +V KP L
Sbjct: 137 SSCLAGSIKRGVNEEDDRRIGLELLNDEKNLLEHDIVVGMIHNAFVSSCSEVEKPDGPVL 196
Query: 305 VRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKS 364
K VQH+ + ++G+L + +FD IE P L G+P+ +A+++I E+E
Sbjct: 197 Y------KTKSVQHLFTPIVGQLRESASIFDLIEKLHPTPALGGSPQEKAVDVIREIEPM 250
Query: 365 RRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMK 424
R Y IG+ +FA+AIR IEG A + AG GIV DS P E+ ET+ K+K
Sbjct: 251 SRGWYAAPIGWIDSQDNGEFAVAIRSGLIEGSTARLFAGCGIVEDSEPISEYEETQIKLK 310
Query: 425 AVLKAFG 431
++ A G
Sbjct: 311 PMISALG 317
>sp|P23973|MENF_BACSU MENAQUINONE-SPECIFIC ISOCHORISMATE SYNTHASE >gi|7428450|pir||A69657
probable isochorismate synthase (EC 5.4.99.6)
menaquinone-specific menF - Bacillus subtilis
>gi|1185288|gb|AAC37013.1| (M74538) isochorismate
synthase [Bacillus subtilis] >gi|2293145|gb|AAC00223.1|
(AF008220) isochorismate synthase [Bacillus subtilis]
>gi|2635567|emb|CAB15061.1| (Z99119)
menaquinone-specific isochorismate synthase [Bacillus
subtilis]
Length = 471
Score = 141 bits (352), Expect = 1e-32
Identities = 97/307 (31%), Positives = 154/307 (49%), Gaps = 24/307 (7%)
Query: 141 DPETIVERAKR-------EELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVV 193
D E ++E K + K E+ + +++++++ +E I +VV
Sbjct: 169 DAEAVLEGLKAFAAEFMVPDFKQEDQAVIAAAEELDKDDWLKAIETATSQIKEKQYDKVV 228
Query: 194 LSREYVLRSD----VDPVELYRKLISINPSPYTFILEFK-KILVGASPETMGSVEGRTVR 248
L+RE +L D ++PV + L+ + Y F +E + K VGASPE + +G TV
Sbjct: 229 LARELLLTFDGPIQIEPV--LKTLLDDQQTSYVFAIEQEGKTFVGASPERLIKRDGGTVM 286
Query: 249 INPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARN----DVRKVSKPGSVKL 304
+ +AG+ RG E+D I LL+DEK EH ++V + N +V KP L
Sbjct: 287 SSCLAGSIKRGVNEEDDRRIGLELLNDEKNLLEHDIVVGMIHNAFVSSCSEVEKPDGPVL 346
Query: 305 VRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKS 364
K VQH+ + ++G+L + +FD IE P L G+P+ +A+++I E+E
Sbjct: 347 Y------KTKSVQHLFTPIVGQLRESASIFDLIEKLHPTPALGGSPQEKAVDVIREIEPM 400
Query: 365 RRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMK 424
R Y IG+ +FA+AIR IEG A + AG GIV DS P E+ ET+ K+K
Sbjct: 401 SRGWYAAPIGWIDSQDNGEFAVAIRSGLIEGSTARLFAGCGIVEDSEPISEYEETQIKLK 460
Query: 425 AVLKAFG 431
++ A G
Sbjct: 461 PMISALG 467
>sp|P50872|TRPE_AZOBR ANTHRANILATE SYNTHASE [INCLUDES: GLUTAMINE AMIDOTRANSFERASE]
>gi|1174156|gb|AAC45141.1| (U44127) anthranilate
synthase [Azospirillum brasilense]
Length = 732
Score = 141 bits (351), Expect = 2e-32
Identities = 94/271 (34%), Positives = 136/271 (49%), Gaps = 12/271 (4%)
Query: 165 RTDANRE--------EFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISI 216
R D N E ++ +VE K GD+F+VV + + P ++R+L +
Sbjct: 236 RPDTNAEAGCDHAPGDYQRVVESAKAAFRRGDLFEVVPGQTFAEPCADAPSSVFRRLRAA 295
Query: 217 NPSPYTFILEFKK--ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLS 274
NP+PY + + LV ASPE V G V PI+GT RG D RLL+
Sbjct: 296 NPAPYEAFVNLGRGEFLVAASPEMYVRVAGGRVETCPISGTVARGADALGDAAQVLRLLT 355
Query: 275 DEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMF 334
K+ AE M D+ RND +V +PGSV+++ + YS + H V G L D
Sbjct: 356 SAKDAAELTMCTDVDRNDKARVCEPGSVRVIGRRMIELYSRLIHTVDHVEGRLRSGMDAL 415
Query: 335 DAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
DA A T+TGAPK AM+ +++ E+S RR YGGA G G D + +R +
Sbjct: 416 DAFLTHSWAVTVTGAPKRWAMQFLEDTEQSPRRWYGGAFGRLGFDGGMDTGLTLRTIRMA 475
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKA 425
A+VRAGA +++DS P+ E + E ++KA
Sbjct: 476 EGVAYVRAGATLLSDSDPDAE--DAECRLKA 504
>pir||A71951 p-aminobenzoate synthetase - Helicobacter pylori (strain J99)
>gi|4154803|gb|AAD05859.1| (AE001465) P-AMINOBENZOATE
SYNTHETASE [Helicobacter pylori J99]
Length = 567
Score = 140 bits (350), Expect = 2e-32
Identities = 109/374 (29%), Positives = 182/374 (48%), Gaps = 38/374 (10%)
Query: 56 GTFLDGKKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFG 115
G F K V T L+ +D S + G F+GY+ Y+A +++ + + + F
Sbjct: 4 GDFKYQKSVKKLTATNLNELKNALDFISQNRGKGYFVGYLLYEARLAFLDENFQSQTPFL 63
Query: 116 YYPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKR--EELKFENGGAEIIRTDANREEF 173
Y+ E +ER K E LK E+ I + +++ +
Sbjct: 64 YF-------------------------EQFLERKKYPLEPLK-EHAFYPKIHSSLDQKTY 97
Query: 174 MEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILE--FKKIL 231
+ + KE++ GD +QV L+ + +L + P +++++I +P+ +E F +L
Sbjct: 98 FKQFKAVKEHLKNGDTYQVNLTMDLLLNTKAKPKRVFKEVIHNQNTPFKAFIENEFGSVL 157
Query: 232 VGASPETMGSVEGRTVRIN----PIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVD 287
SPE +E I P+ GT R P DE+ R L +D+K R+E+VM+VD
Sbjct: 158 -SFSPELFFELEFLDTAIKIITKPMKGTIARSNNPLIDEKNRLFLQNDDKNRSENVMIVD 216
Query: 288 LARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLT 347
L RND+ +++ SVK+ + F++I V + SE+ +L +F+ +A FP G++T
Sbjct: 217 LLRNDLSRLALKNSVKVNQLFEIISLPSVYQMISEIEAQLPLKTSLFEIFKALFPCGSVT 276
Query: 348 GAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRK--AHVRAGAG 405
G PKI+ M+II+ LEK R VY GAIG A F++ IR E + H+ G+G
Sbjct: 277 GCPKIKTMQIIESLEKRPRGVYCGAIGMVG-GKKALFSVPIRTLEKRAHEDFLHLGVGSG 335
Query: 406 IVADSIPEKEFYET 419
+ S KE+ E+
Sbjct: 336 VTYKSKASKEYEES 349
>emb|CAB46570.1| (AJ132668) salicylate synthetase, Irp9 [Yersinia enterocolitica]
Length = 434
Score = 140 bits (350), Expect = 2e-32
Identities = 91/265 (34%), Positives = 140/265 (52%), Gaps = 4/265 (1%)
Query: 164 IRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVD--PVELYRKLISINPSPY 221
+ T N E + + V + I G+ +V++SR L S +D LY + + +
Sbjct: 166 VDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSF 225
Query: 222 TFILEFKKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAE 281
F E ++ L G SPE + SV G V P+AGT R PE ++ LL D KE E
Sbjct: 226 MFRQEGREAL-GFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLE 284
Query: 282 HVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF 341
H++ V A ++ V PGSV + V + VQH+ S V G+LA++KD +DA F
Sbjct: 285 HILSVKEAIAELEAVCLPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLF 344
Query: 342 PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVR 401
P+ T +G PK A+ I ++EK+ R +Y GAI T + D A+ +R + ++ ++
Sbjct: 345 PSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRF-DAALVLRSVFQDSQRCWIQ 403
Query: 402 AGAGIVADSIPEKEFYETENKMKAV 426
AGAGI+A S PE+E ET K+ ++
Sbjct: 404 AGAGIIAQSTPERELTETREKLASI 428
>pir||E64556 para-aminobenzoate synthetase - Helicobacter pylori (strain 26695)
>gi|2313385|gb|AAD07357.1| (AE000547) para-aminobenzoate
synthetase (pabB) [Helicobacter pylori 26695]
Length = 559
Score = 138 bits (344), Expect = 1e-31
Identities = 109/374 (29%), Positives = 181/374 (48%), Gaps = 38/374 (10%)
Query: 56 GTFLDGKKVSNETNPFLSLKSFNMDSASGSGFLGGFMGYIAYDAVHNYIEGSIEEPSVFG 115
G F K V T L+ +D S + G F+GY+ Y+A +++ + + + F
Sbjct: 4 GDFKYQKSVKKLTATNLNELKNALDFISQNRGNGYFVGYLLYEARLAFLDENFQSQTPFL 63
Query: 116 YYPWVFIYNHGKGELRFYYLRDPSFDPETIVERAKR--EELKFENGGAEIIRTDANREEF 173
Y+ E +ER K E LK E+ I + +++ +
Sbjct: 64 YF-------------------------EQFLERKKYSLEPLK-EHAFYPKIHSSLDQKTY 97
Query: 174 MEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPSPYTFILE--FKKIL 231
+ + KE + GD +QV L+ + L + P ++++++ +P+ +E F +L
Sbjct: 98 FKQFKAVKERLKNGDTYQVNLTMDLFLDTKAKPKRVFKEVVHNQNTPFKAFIENEFGSVL 157
Query: 232 VGASPETMGSVEGRTVRIN----PIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVD 287
SPE +E I P+ GT R K P DE+ R L +D+K R+E+VM+VD
Sbjct: 158 -SFSPELFFELEFLDTAIKIITKPMKGTIARSKNPLIDEKNRLFLQNDDKNRSENVMIVD 216
Query: 288 LARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLT 347
L RND+ +++ SVK+ + F++I V + SE+ +L +F+ +A FP G++T
Sbjct: 217 LLRNDLSRLALKNSVKVNQLFEIISLPSVYQMISEIEAKLPLKTSLFEIFKALFPCGSVT 276
Query: 348 GAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAE--IEGRKAHVRAGAG 405
G PKI+ M+II+ LEK R VY GAIG A F++ IR E + H+ G+G
Sbjct: 277 GCPKIKTMQIIESLEKRPRGVYCGAIGMVE-EKKALFSVPIRTLEKRVHENFLHLGVGSG 335
Query: 406 IVADSIPEKEFYET 419
+ S KE+ E+
Sbjct: 336 VTYKSKAPKEYEES 349
>pir||T40823 probable para-aminobenzoate synthase - fission yeast
(Schizosaccharomyces pombe) >gi|3810853|emb|CAA21814.1|
(AL032684) probable para-aminobenzoate synthase
[Schizosaccharomyces pombe]
Length = 718
Score = 134 bits (333), Expect = 2e-30
Identities = 82/273 (30%), Positives = 149/273 (54%), Gaps = 7/273 (2%)
Query: 163 IIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRS--DVDPVELYRKLISINPSP 220
++++ +E + E V+ +E++ AGD +++ L+ + + ++ E+Y + S+NP+
Sbjct: 437 LVQSFPKKEVYCESVKACQEHLLAGDSYEMCLTDTTFVSAPPELSDFEMYMRARSLNPAT 496
Query: 221 YTFILEFKKI-LVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKER 279
+ + L+ SPE +PI GT R + EE R++LL+ EK+
Sbjct: 497 FAGFVRLNHFTLLCCSPERFLQFRDDRCLFSPIKGTLKR-EGHMSLEEARKKLLN-EKDM 554
Query: 280 AEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEA 339
E M++DL RND+ +++K SV + + V ++S+V + S + G + +D +
Sbjct: 555 GELNMIIDLIRNDLHQLAKKNSVHVPELYSVEEHSNVYSLLSNIYGRIESPITAWDVLSK 614
Query: 340 SFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAH 399
SFP G++TGAPK+R++ +++ LE+ R +Y G +GY+ +TG A+F + IR A +
Sbjct: 615 SFPPGSMTGAPKLRSVRMLEPLEQHGRGIYSGTLGYWDVTGSAEFNVIIRSAFKYKADDY 674
Query: 400 VRAGAG--IVADSIPEKEFYETENKMKAVLKAF 430
R GAG + S PE E+ E K ++L AF
Sbjct: 675 WRIGAGGAVTILSSPEGEYEEMVLKANSILPAF 707
>gb|AAC43275.1| (U07755) p-aminobenzoate synthetase [Escherichia coli]
>gi|468181|gb|AAC43283.1| (U07764) p-aminobenzoate
synthetase [Escherichia coli]
Length = 336
Score = 131 bits (327), Expect = 1e-29
Identities = 95/340 (27%), Positives = 160/340 (46%), Gaps = 26/340 (7%)
Query: 37 AKLTYISASPEFTVEISGKGTFL-DGKKVSNETNPFLSLKSFNMDSAS-------GSGFL 88
++ + A P T+ GK T + + +K + T+ L + +D A F
Sbjct: 3 SRFDIVVADPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQ 62
Query: 89 GGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPSFD 141
GG +G YD + E I P + G Y W I +H + + D +
Sbjct: 63 GGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDVN-- 120
Query: 142 PETIVERAKREELKFENGGAEIIRTD----ANREEFMEMVEKGKEYIFAGDVFQVVLSRE 197
RA E +F + +D RE++ E + +EY+ +GD +QV L++
Sbjct: 121 ----ARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQR 176
Query: 198 YVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTA 256
+ D + + +L N +P++ L ++ ++ SPE + ++ PI GT
Sbjct: 177 FHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTL 236
Query: 257 PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHV 316
PR P+ED + +L + K+RAE++M+VDL RND+ +V+ GSVK+ F V + V
Sbjct: 237 PRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 296
Query: 317 QHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAME 356
H+ S + L + D + A+FP G++TGAPK+RAME
Sbjct: 297 HHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAME 336
>gb|AAC43269.1| (U07748) p-aminobenzoate synthetase [Escherichia coli]
>gi|468155|gb|AAC43270.1| (U07749) p-aminobenzoate
synthetase [Escherichia coli] >gi|468179|gb|AAC43282.1|
(U07762) p-aminobenzoate synthetase [Escherichia coli]
Length = 336
Score = 131 bits (326), Expect = 2e-29
Identities = 95/340 (27%), Positives = 161/340 (46%), Gaps = 26/340 (7%)
Query: 37 AKLTYISASPEFTVEISGKGTFL-DGKKVSNETNPFLSLKSFNMDSAS-------GSGFL 88
++ + A P T+ GK T + + +K + T+ L + +D A F
Sbjct: 3 SRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQ 62
Query: 89 GGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPSFD 141
GG +G YD + E I P + G Y W I +H + + D +
Sbjct: 63 GGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDVN-- 120
Query: 142 PETIVERAKREELKFENGGAEIIRTD----ANREEFMEMVEKGKEYIFAGDVFQVVLSRE 197
RA E +F + +D RE++ E + +EY+ +GD +QV L++
Sbjct: 121 ----ARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQR 176
Query: 198 YVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTA 256
+ D + + +L N +P++ L ++ ++ SPE + ++ PI GT
Sbjct: 177 FHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTL 236
Query: 257 PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHV 316
PR P+ED + +L + K+RAE++M+VDL RND+ +V+ GSVK+ F V + V
Sbjct: 237 PRLPDPQEDSKQAVKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 296
Query: 317 QHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAME 356
H+ S + +L + D + A+FP G++TGAPK+RAME
Sbjct: 297 HHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAME 336
>gb|AAC43276.1| (U07756) p-aminobenzoate synthetase [Escherichia coli]
Length = 336
Score = 131 bits (326), Expect = 2e-29
Identities = 93/340 (27%), Positives = 161/340 (47%), Gaps = 26/340 (7%)
Query: 37 AKLTYISASPEFTVEISGKGTFL-DGKKVSNETNPFLSLKSFNMDSAS-------GSGFL 88
++ + A P T+ GK T + + +K + T+ L + +D A F
Sbjct: 3 SRFDIVVAEPICTLTTFGKETVVSENEKRTTTTDDPLQVLQQVLDRADIRPAHNEDLPFQ 62
Query: 89 GGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPSFD 141
GG +G YD + + I P + G Y W + +H + + D +
Sbjct: 63 GGALGLFGYDLGRRFESLPEIAQQDIVLPDMAVGIYDWALVVDHQRQTVSLLSHNDVN-- 120
Query: 142 PETIVERAKREELKFENGGAEIIRTD----ANREEFMEMVEKGKEYIFAGDVFQVVLSRE 197
RA E +F + +D RE++ E + +EY+ +GD +QV L++
Sbjct: 121 ----ARRAWLESQQFSPQEDFALTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQR 176
Query: 198 YVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTA 256
+ D + + +L N +P++ L ++ ++ SPE + ++ PI GT
Sbjct: 177 FQAAYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTL 236
Query: 257 PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHV 316
PR P+ED + +L + K+RAE++M+VDL RND+ +V+ GSVK+ F V + V
Sbjct: 237 PRLPDPQEDSKQAEKLANSPKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 296
Query: 317 QHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAME 356
H+ S + +L + D + A+FP G++TGAPK+RAME
Sbjct: 297 HHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAME 336
>gb|AAC43278.1| (U07758) p-aminobenzoate synthetase [Escherichia coli]
>gi|468175|gb|AAC43280.1| (U07760) p-aminobenzoate
synthetase [Escherichia coli] >gi|468177|gb|AAC43281.1|
(U07761) p-aminobenzoate synthetase [Escherichia coli]
Length = 336
Score = 131 bits (326), Expect = 2e-29
Identities = 94/340 (27%), Positives = 160/340 (46%), Gaps = 26/340 (7%)
Query: 37 AKLTYISASPEFTVEISGKGTFL-DGKKVSNETNPFLSLKSFNMDSAS-------GSGFL 88
++ + A P T+ GK T + + +K + T+ L + +D A F
Sbjct: 3 SRFDIVVAEPLCTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPAHNEDLPFQ 62
Query: 89 GGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPSFD 141
GG +G YD + E I P + G Y W + +H + + D +
Sbjct: 63 GGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALVVDHQRQTVSLLSHNDVN-- 120
Query: 142 PETIVERAKREELKFENGGAEIIRTD----ANREEFMEMVEKGKEYIFAGDVFQVVLSRE 197
RA E +F + +D RE++ E + +EY+ +GD +QV L++
Sbjct: 121 ----ARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQR 176
Query: 198 YVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTA 256
+ D + + +L N +P++ L ++ ++ SPE + ++ PI GT
Sbjct: 177 FHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTL 236
Query: 257 PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHV 316
PR P+ED + +L + K+RAE++M+VDL RND+ +V+ GSVK+ F V + V
Sbjct: 237 PRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 296
Query: 317 QHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAME 356
H+ S + L + D + A+FP G++TGAPK+RAME
Sbjct: 297 HHLVSTITARLPEQLHTSDLLRAAFPGGSITGAPKVRAME 336
>gb|AAC43277.1| (U07757) p-aminobenzoate synthetase [Escherichia coli]
Length = 336
Score = 130 bits (324), Expect = 3e-29
Identities = 93/340 (27%), Positives = 160/340 (46%), Gaps = 26/340 (7%)
Query: 37 AKLTYISASPEFTVEISGKGTFL-DGKKVSNETNPFLSLKSFNMDSAS-------GSGFL 88
++ + A P T+ GK T + + +K + T+ L + +D A F
Sbjct: 3 SRFDIVVAEPICTLTTFGKETVVSENEKRTTTTDDPLQVLQQVLDRADIRPAHNEDLPFQ 62
Query: 89 GGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPSFD 141
GG +G YD + + I P + G Y W + +H + + D +
Sbjct: 63 GGALGLFGYDLGRRFESLPEIAQQDIVLPDMAVGIYDWALVVDHQRQTVSLLSHNDVN-- 120
Query: 142 PETIVERAKREELKFENGGAEIIRTD----ANREEFMEMVEKGKEYIFAGDVFQVVLSRE 197
RA E +F + +D RE++ E + +EY+ GD +QV L++
Sbjct: 121 ----ARRAWLESQQFSPQEDFALTSDWQSNMTREQYGEKFRQVQEYLHRGDCYQVNLAQR 176
Query: 198 YVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTA 256
+ D + + +L N +P++ L ++ ++ SPE + ++ PI GT
Sbjct: 177 FQAAYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTL 236
Query: 257 PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHV 316
PR P+ED + +L + K+RAE++M+VDL RND+ +V+ GSVK+ F V + V
Sbjct: 237 PRLPDPQEDSKQAEKLANSPKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 296
Query: 317 QHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAME 356
H+ S + +L + D + A+FP G++TGAPK+RAME
Sbjct: 297 HHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAME 336
>gb|AAG31127.1|AF299336_4 (AF299336) MxcD [Stigmatella aurantiaca]
Length = 408
Score = 129 bits (320), Expect = 8e-29
Identities = 91/280 (32%), Positives = 137/280 (48%), Gaps = 24/280 (8%)
Query: 173 FMEMVEKGKEYIFAGDVFQVVLSREYVLRSD--VDPVELYRKLISINPSPYTFILEF--- 227
+++ V + + + G + +VVLSR L + +D +L R L NPS YTF ++
Sbjct: 129 YLDGVTQALKLMQTGSLRKVVLSRSLHLSATTPIDLPQLLRNLAQRNPSGYTFAVDLPPG 188
Query: 228 --------KKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKER 279
++ L+GASPE + S G V NP+AG+A R P ED+E LL K+
Sbjct: 189 ATQAAGGLRRTLIGASPELLVSRSGLQVLANPLAGSAARSANPIEDQERAATLLKSSKDL 248
Query: 280 AEHVMLVDLARNDVR----KVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFD 335
EH ++++ +R K+ P LV + H+ S + GELAD
Sbjct: 249 HEHAVVIEAVVEAMRPYCKKLDVPSGPSLV------STQTMWHLSSRICGELADPSITSL 302
Query: 336 AIEASF-PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIE 394
A+ + P + G P A E I +E +R Y G +G+ +G +A+ IR AE +
Sbjct: 303 ALAVALHPTPAVCGYPTELAHEAITTIEPFQRGFYTGTVGWCDASGDGQWAVTIRCAEAD 362
Query: 395 GRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVIQ 434
R + AGAGIV S PE E ETE K + +L+A G+ Q
Sbjct: 363 ERTLRLFAGAGIVVGSKPESELAETEAKFRTMLQAMGLGQ 402
>pir||F81359 para-aminobenzoate synthase component I (EC 4.1.3.-) Cj0862c
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968308|emb|CAB73127.1| (AL139076)
para-aminobenzoate synthase component I [Campylobacter
jejuni]
Length = 594
Score = 128 bits (318), Expect = 1e-28
Identities = 87/290 (30%), Positives = 149/290 (51%), Gaps = 7/290 (2%)
Query: 134 YLRDPSFDPETIVERAKREELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVV 193
YL +F ++ +E KF + D +E F+++ KE I G V+Q+
Sbjct: 68 YLSVFAFKKRKKFQKEDIDEEKFIPEFINFLDQDNYKENFIKV----KEAISKGRVYQIN 123
Query: 194 LSREYVLRSDVDPVELYRKLISINPSPY-TFILEFKKILVGASPETMGSVEGRTVRINPI 252
L++ + S +D EL++ L+S + + FI + + ++ SPE + R + P+
Sbjct: 124 LTQNFKFHSKMDSFELFKLLLSRQDTEFKAFIKDETREILSFSPELFFKTKKRKIFTKPM 183
Query: 253 AGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIK 312
GT R K P +DEE + L +D K +E+VM+ DL RND+ K+ S+K + F++
Sbjct: 184 KGTIKRDKDPIKDEENKIFLQNDTKNLSENVMICDLLRNDLSKIITKKSLK-TKLFEIQS 242
Query: 313 YSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGA 372
+ + + S G+L + + +A FP G++TGAPK+ +++ I+ELE+ R +Y G
Sbjct: 243 HPTLHQMTSRAQGKLKKNISLHQIFKALFPCGSITGAPKLESIKFIEELEQRDRGIYCGT 302
Query: 373 IGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENK 422
IG F++AIR E + G+G+V DS + EF E + K
Sbjct: 303 IGLIH-KNKNKFSVAIRTLEKQDEIYTYSTGSGLVWDSKFKDEFEELKLK 351
>gb|AAC43279.1| (U07759) p-aminobenzoate synthetase [Escherichia coli]
Length = 336
Score = 127 bits (317), Expect = 2e-28
Identities = 92/340 (27%), Positives = 160/340 (47%), Gaps = 26/340 (7%)
Query: 37 AKLTYISASPEFTVEISGKGTFL-DGKKVSNETNPFLSLKSFNMDSAS-------GSGFL 88
++ + A P T+ GK T + + +K + T+ L + +D A F
Sbjct: 3 SRFDIVVAEPICTLTTFGKETVVSESEKCTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQ 62
Query: 89 GGFMGYIAYDAVHNY------IEGSIEEPSV-FGYYPWVFIYNHGKGELRFYYLRDPSFD 141
GG +G YD + + I P + G Y W + +H + + D +
Sbjct: 63 GGALGLFGYDLGRRFESLPEIAQQDIVLPDMAVGIYDWALVVDHQRQTVSLLSHNDVN-- 120
Query: 142 PETIVERAKREELKFENGGAEIIRTD----ANREEFMEMVEKGKEYIFAGDVFQVVLSRE 197
RA E +F + +D RE++ E + +EY+ +GD +QV L++
Sbjct: 121 ----ARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQR 176
Query: 198 YVLRSDVDPVELYRKLISINPSPYTFILEFKK-ILVGASPETMGSVEGRTVRINPIAGTA 256
+ D + + +L N +P++ L ++ ++ SPE + ++ PI GT
Sbjct: 177 FHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGTILSLSPERFILCDNSEIQTRPIKGTL 236
Query: 257 PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHV 316
PR +ED + +L + K+RAE++M+VDL RND+ +V+ GSVK+ F V + V
Sbjct: 237 PRLPDLQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 296
Query: 317 QHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAME 356
H+ S + +L + D + A+FP G++TGAPK+RAME
Sbjct: 297 HHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAME 336
>sp|P45744|DHBC_BACSU ISOCHORISMATE SYNTHASE DHBC >gi|7428452|pir||C69615 isochorismate
synthase dhbC - Bacillus subtilis
>gi|837331|gb|AAC44631.1| (U26444) isochorismate
synthase [Bacillus subtilis] >gi|2635696|emb|CAB15189.1|
(Z99120) isochorismate synthase [Bacillus subtilis]
Length = 398
Score = 127 bits (315), Expect = 3e-28
Identities = 94/293 (32%), Positives = 141/293 (48%), Gaps = 15/293 (5%)
Query: 152 EELKFENGGAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPV---E 208
EE + + G I+ E++ VE+G I G + ++VLSR L S +P+ E
Sbjct: 106 EEKEQQAGHTYHIKPVPEPEDYKNGVEQGLARIADGTLSKIVLSRSLHLTSP-EPIQTDE 164
Query: 209 LYRKLISINPSPYTFILEF--------KKILVGASPETMGSVEGRTVRINPIAGTAPRGK 260
L R L N YTF + ++ L+GASPE + S G V NP+AG+ PR
Sbjct: 165 LLRHLAQHNSHGYTFAADVSSQEETSPRRTLLGASPELLVSRMGTQVVSNPLAGSRPRSN 224
Query: 261 TPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIE 320
P ED+ LLS K+ EH ++ D +R + ++++ +IK + H+
Sbjct: 225 DPVEDQRRAAELLSPAKDLHEHAVVADAVAAALRPFCR--TLEVPEKPSLIKTETMWHLS 282
Query: 321 SEVIGELADDK-DMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSIT 379
S + GEL+D + A P + G P A E I +E R + G +G+
Sbjct: 283 SVIKGELSDPSVTALELAAALHPTPAVCGTPTDLAREAILSIEPFDRGFFTGMVGWCDDA 342
Query: 380 GYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
G ++ + IR AE E R + AGAG+VA S PE E ET K + +L+A GV
Sbjct: 343 GDGEWIVTIRCAEAEERSLRLYAGAGVVAGSKPEDELQETSAKFRTMLRAMGV 395
>gb|AAF89583.1|AF166096_1 (AF166096) para-aminobenzoic acid synthetase [Coprinus cinereus]
Length = 752
Score = 118 bits (292), Expect = 2e-25
Identities = 87/290 (30%), Positives = 156/290 (53%), Gaps = 31/290 (10%)
Query: 170 REEFMEMVEKGKEYIFAGDVFQVVLSREYVL---------RSDVDPVELYRKLISINPSP 220
+++++ +++ KEY+++GD +++ L+ + + + E Y +L NP+P
Sbjct: 450 QDQYIYKIKQAKEYLYSGDSYELCLTAQTKILIPHQQSKGSTTSTSWERYLRLREKNPAP 509
Query: 221 YT-FILEFKKILVGASPETMGSVEG---RTVRINPIAGTAPRGKTPEEDEEIRRRLLSDE 276
++ +I L+ +SPE S ++ PI GT +G P E+ +LL+
Sbjct: 510 HSAYIRLHPTTLMSSSPERFLSYSRPPHSVCQLRPIKGTVRKG--PGITREVATQLLAGS 567
Query: 277 -KERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGE-----LADD 330
KE AE++M+VDL R+D+ V +V + +F V +Y V + S + G+ ++
Sbjct: 568 PKEVAENLMIVDLIRHDLHGVVGD-NVVVSKFCGVEEYETVWQLVSVIEGKEDPSASVEE 626
Query: 331 KDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRM 390
+ ++ ++AS P GT+TGAPK R++EI+ LE + R VY G GY+ I G D+++ IR
Sbjct: 627 ELGWNVLKASLPPGTMTGAPKKRSVEILQHLEGAEREVYSGVFGYWDIGGGGDWSVTIRS 686
Query: 391 A-EIEGRKAH--------VRAGAGIVADSIPEKEFYETENKMKAVLKAFG 431
+ + R + + AG I A S P+ E+ E E K+++VLK+FG
Sbjct: 687 CFKYDDRSSSKDKTEEWAIGAGGAITALSDPDAEWDEMEVKLQSVLKSFG 736
>sp|O07898|VIBC_VIBCH VIBRIOBACTIN-SPECIFIC ISOCHORISMATE SYNTHASE
>gi|11270739|pir||A82283 vibriobactin-specific
isochorismate synthase VC0773 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|2182763|gb|AAC45925.1| (U52150) isochorismate
synthase [Vibrio cholerae] >gi|9655220|gb|AAF93938.1|
(AE004162) vibriobactin-specific isochorismate synthase
[Vibrio cholerae]
Length = 395
Score = 114 bits (282), Expect = 2e-24
Identities = 76/247 (30%), Positives = 131/247 (52%), Gaps = 7/247 (2%)
Query: 191 QVVLSR--EYVLRSDVDPVELYRKLISINPSPYTFI--LEFKKILVGASPETMGSVEGRT 246
+VVLSR E ++ L R L++IN YTF L+ ++ L+GASPE + + G
Sbjct: 143 KVVLSRAIEIATEQEIALPTLLRSLLAINHHGYTFAASLDEQRKLIGASPELLVAKRGNY 202
Query: 247 VRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVR 306
+ NP+AG+ PR + +E+ + R LL+ K+ EH ++V+ + + + +V
Sbjct: 203 LISNPLAGSRPRSQDAQENAQRRASLLNTAKDLHEHGLVVEEVERIMSRYCRNLYTPMVP 262
Query: 307 FFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF-PAGTLTGAPKIRAMEIIDELEKSR 365
VI+ + H+ + + G+++D + + A P + G P+ A + I ELE+
Sbjct: 263 --SVIETETMLHLSTLLEGQVSDPEVCALQVAADLHPTPAVCGFPRESAYQAIRELEEFD 320
Query: 366 RRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKA 425
R + G +G+ G ++ + IR AE+ + + AGAGIV +S+P+ E ET KMK
Sbjct: 321 RGYFTGMVGWCDARGNGEWVVTIRCAEVGSHQMKLFAGAGIVDESLPQSELEETGAKMKT 380
Query: 426 VLKAFGV 432
+L A G+
Sbjct: 381 ILAAAGI 387
>pir||A81021 para-aminobenzoate synthetase component I/
4-amino-4-deoxychorismate lyase, probable NMB1970
[imported] - Neisseria meningitidis (group B strain
MD58) >gi|7227231|gb|AAF42299.1| (AE002545)
para-aminobenzoate synthetase component
I/4-amino-4-deoxychorismate lyase, putative [Neisseria
meningitidis MC58]
Length = 593
Score = 112 bits (277), Expect = 9e-24
Identities = 81/276 (29%), Positives = 132/276 (47%), Gaps = 20/276 (7%)
Query: 160 GAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPS 219
G + + ++++ + + E I GD +Q+ + L++ +PV LYR+L P
Sbjct: 99 GISTPQPSVSETDYLDRIRQIHEAIRRGDTYQINYTTRLHLQAYGNPVSLYRRLRQ--PV 156
Query: 220 PYTFILEFKKI------LVGASPETMGSV-EGRTVRINPIAGTAPRGKTPEEDEEIRRRL 272
PY + + SPE + T+ P+ GTAP +DE L
Sbjct: 157 PYAVLSHLPDAEGQSAWTLCFSPELFLKIGSDGTISTEPMKGTAPI-LGDGQDERRAAEL 215
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+D K RAE+VM+VDL RND+ K+++ G+V + F V ++ V + S + +
Sbjct: 216 QADPKNRAENVMIVDLLRNDLGKIAQTGTVCVPEPFKVSRFGSVWQMTSTIQAQALPHTS 275
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFS-----ITGYADFAIA 387
D + A+FP G++TGAPK +M+II+ LE R +Y G+IGY + + F +
Sbjct: 276 FADILRAAFPCGSITGAPKKMSMQIIESLEAEARGLYTGSIGYLNPCSGGLGFEGTFNVV 335
Query: 388 IRMAEIEGRKAHV-----RAGAGIVADSIPEKEFYE 418
IR + + G+GIV DS P E+ E
Sbjct: 336 IRTLSLTPLSDGIYQGVYGVGSGIVIDSDPAAEYRE 371
>pir||D81965 probable para-aminobenzoate synthase component I NMA0477 [imported]
- Neisseria meningitidis (group A strain Z2491)
>gi|7379223|emb|CAB83772.1| (AL162753) putative
para-aminobenzoate synthase component I [Neisseria
meningitidis Z2491]
Length = 598
Score = 111 bits (275), Expect = 2e-23
Identities = 80/276 (28%), Positives = 134/276 (47%), Gaps = 20/276 (7%)
Query: 160 GAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKLISINPS 219
G ++ + ++++ + + E I GD +Q+ + L++ +PV+LY++L P
Sbjct: 104 GISTPQSSVSEADYLDHIRQIHEAIRRGDTYQINYTTRLHLQAYGNPVKLYQRLRQ--PV 161
Query: 220 PYTFILEFKKI------LVGASPETMGSV-EGRTVRINPIAGTAPRGKTPEEDEEIRRRL 272
PY + + SPE + T+ P+ GTAP +DE L
Sbjct: 162 PYAVLSHLPDAQGQSAWTLCFSPELFLKIGSDGTISTEPMKGTAPI-LGDGQDERRAAEL 220
Query: 273 LSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKD 332
+D K RAE+VM+VDL RND+ K+++ G+V + F V ++ V + S + +
Sbjct: 221 QADPKNRAENVMIVDLLRNDLGKIAQTGTVCVPEPFKVSRFGSVWQMTSTIQAQALPHTS 280
Query: 333 MFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFS-----ITGYADFAIA 387
D + A+FP G++TGAPK +M+II+ LE R +Y G+IGY + + F +
Sbjct: 281 FADILRAAFPCGSITGAPKKMSMQIIESLEAEARGLYTGSIGYLNPCSGGLGFEGTFNVV 340
Query: 388 IRMAEIEGRKAHV-----RAGAGIVADSIPEKEFYE 418
IR + + G+GIV DS P E+ E
Sbjct: 341 IRTLSLTPLSDGIYQGVYGVGSGIVIDSDPAAEYRE 376
>pir||H70595 probable entC protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2072670|emb|CAB08301.1| (Z95120) entC [Mycobacterium
tuberculosis]
Length = 372
Score = 108 bits (268), Expect = 1e-22
Identities = 83/263 (31%), Positives = 127/263 (47%), Gaps = 16/263 (6%)
Query: 185 FAGDVFQVVLSREYVLRSD--VDPVELYRKLISINPSPYTFILEFKKI--------LVGA 234
F G + +VVL+R L +D +D L R+L+ +P+ Y ++++ LVGA
Sbjct: 113 FDGPLHKVVLARAVQLTADAPLDARVLLRRLVVADPTAYGYLVDLTSAGNDDTGAALVGA 172
Query: 235 SPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVR 294
SPE + + G V P AG+APR P+ D L S K R EH ++VD R +
Sbjct: 173 SPELLVARSGNRVMCKPFAGSAPRAADPKLDAANAAALASSAKNRHEHQLVVDTMRVALE 232
Query: 295 KVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELAD-DKDMFDAIEASFPAGTLTGAPKIR 353
+ + ++ + + + V H+ + + G L + D A P + G P
Sbjct: 233 PLCEDLTIPAQP--QLNRTAAVWHLCTAITGRLRNISTTAIDLALALHPTPAVGGVPTKA 290
Query: 354 AMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEI--EGRKAHVRAGAGIVADSI 411
A E+I ELE R Y GA+G+ G + ++IR A++ + R A AG GIVA+S
Sbjct: 291 ATELIAELE-GDRGFYAGAVGWCDGRGDGHWVVSIRCAQLSADRRAALAHAGGGIVAESD 349
Query: 412 PEKEFYETENKMKAVLKAFGVIQ 434
P+ E ET K +L A GV Q
Sbjct: 350 PDDELEETTTKFATILTALGVEQ 372
>sp|P10377|ENTC_ECOLI ISOCHORISMATE SYNTHASE ENTC >gi|68479|pir||SYECIK isochorismate
synthase (EC 5.4.99.6) [validated] - Escherichia coli
>gi|450376|gb|AAA16100.1| (M24142) isochorismate
synthase [Escherichia coli] >gi|1786809|gb|AAC73694.1|
(AE000165) isochorismate hydroxymutase 2, enterochelin
biosynthesis [Escherichia coli K12]
Length = 391
Score = 106 bits (263), Expect = 4e-22
Identities = 80/268 (29%), Positives = 127/268 (46%), Gaps = 14/268 (5%)
Query: 173 FMEMVEKGKEYIFAGDVFQVVLSREYVLRSD--VDPVELYRKLISINPSPYTFILEFKK- 229
F +MV + V +VVLSR + +D +D L +LI+ NP Y F +
Sbjct: 129 FEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADG 188
Query: 230 -ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDL 288
+L+GASPE + +G P+AG+A R D E RLL+ EK+R EH ++
Sbjct: 189 GVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQA 248
Query: 289 ARNDVRKVSK----PGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAG 344
+ +R+ S P S +L I + H+ + G+ ++ P
Sbjct: 249 MKEVLRERSSELHVPSSPQL------ITTPTLWHLATPFEGKANSQENALTLACLLHPTP 302
Query: 345 TLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGA 404
L+G P A ++I ELE R ++GG +G+ G ++ + IR A++ + + AGA
Sbjct: 303 ALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGA 362
Query: 405 GIVADSIPEKEFYETENKMKAVLKAFGV 432
GIV S P E+ ET K+ +L FG+
Sbjct: 363 GIVPASSPLGEWRETGVKLSTMLNVFGL 390
>gb|AAB40793.1| (U82598) isochorismate synthase [Escherichia coli]
Length = 395
Score = 106 bits (263), Expect = 4e-22
Identities = 80/268 (29%), Positives = 127/268 (46%), Gaps = 14/268 (5%)
Query: 173 FMEMVEKGKEYIFAGDVFQVVLSREYVLRSD--VDPVELYRKLISINPSPYTFILEFKK- 229
F +MV + V +VVLSR + +D +D L +LI+ NP Y F +
Sbjct: 133 FEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADG 192
Query: 230 -ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDL 288
+L+GASPE + +G P+AG+A R D E RLL+ EK+R EH ++
Sbjct: 193 GVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQA 252
Query: 289 ARNDVRKVSK----PGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAG 344
+ +R+ S P S +L I + H+ + G+ ++ P
Sbjct: 253 MKEVLRERSSELHVPSSPQL------ITTPTLWHLATPFEGKANSQENALTLACLLHPTP 306
Query: 345 TLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGA 404
L+G P A ++I ELE R ++GG +G+ G ++ + IR A++ + + AGA
Sbjct: 307 ALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGA 366
Query: 405 GIVADSIPEKEFYETENKMKAVLKAFGV 432
GIV S P E+ ET K+ +L FG+
Sbjct: 367 GIVPASSPLGEWRETGVKLSTMLNVFGL 394
>gb|AAA18491.1| (M36700) iron chelator protein [Escherichia coli]
Length = 391
Score = 106 bits (261), Expect = 7e-22
Identities = 80/268 (29%), Positives = 126/268 (46%), Gaps = 14/268 (5%)
Query: 173 FMEMVEKGKEYIFAGDVFQVVLSREYVLRSD--VDPVELYRKLISINPSPYTFILEFKK- 229
F +MV + V +VVLSR + +D +D L +LI+ NP Y F +
Sbjct: 129 FEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADG 188
Query: 230 -ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDL 288
+L+GASPE + +G P+AG+A R D E RLL+ EK+R EH ++
Sbjct: 189 GVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQA 248
Query: 289 ARNDVRKVSK----PGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAG 344
+ +R+ S P S +L I + H+ + G+ ++ P
Sbjct: 249 MKEVLRERSSELHVPSSPQL------ITTPTLWHLATPFEGKANSQENALTLACLLHPTP 302
Query: 345 TLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGA 404
LT P A ++I ELE R ++GG +G+ G ++ + IR A++ + + AGA
Sbjct: 303 ALTAFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGA 362
Query: 405 GIVADSIPEKEFYETENKMKAVLKAFGV 432
GIV S P E+ ET K+ +L FG+
Sbjct: 363 GIVPASSPLGEWRETGVKLSTMLNVFGL 390
>gi|6324361 para-aminobenzoate synthase, PABA synthase; Abz1p [Saccharomyces
cerevisiae] >gi|2132374|pir||S63364 p-aminobenzoate
synthase (EC 4.1.3.-) - yeast (Saccharomyces cerevisiae)
>gi|1302531|emb|CAA96313.1| (Z71648) ORF YNR033w
[Saccharomyces cerevisiae]
Length = 787
Score = 106 bits (261), Expect = 7e-22
Identities = 95/393 (24%), Positives = 182/393 (46%), Gaps = 54/393 (13%)
Query: 87 FLGGFMGYIAYDAVHNYI--------EGSIEEPSVFGYYPWVFIYNHGKGEL-------R 131
F+GG +G + Y+ + YI E S+ + + + NH +G+L
Sbjct: 399 FIGGLVGILGYE-IGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLYCISLDNT 457
Query: 132 FYYLRDPSFDPETIVERAKREEL---KFENGGAEIIRTDANREEFMEMVEKGKEYIFAGD 188
F + S + ++ ++ L K+ + I T ++ ++ + +K ++Y+ GD
Sbjct: 458 FPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKKCQDYMHKGD 517
Query: 189 VFQVVLSRE--YVLRSDVDPVELYRKLISINPSPYTFILEFKKIL------------VGA 234
+++ L+ + V + ++P +++ L+ NP+P++ EFK I+ +
Sbjct: 518 SYEMCLTTQTKVVPSAVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQDETPPVLCFLST 577
Query: 235 SPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVR 294
SPE + T + PI GT +G P+ + R+L KE E++M++DL RND+
Sbjct: 578 SPERFLKWDADTCELRPIKGTVKKG--PQMNLAKATRILKTPKEFGENLMILDLIRNDLY 635
Query: 295 KVSKPGSVKLVRFFDVIKYSHVQHIESEVIGE---LADDKDMF---DAIEASFPAGTLTG 348
++ V++ F V +Y+ V + S V A K + D ++ S P G++TG
Sbjct: 636 ELVP--DVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVLKHSLPPGSMTG 693
Query: 349 APKIRAMEIIDELEKSR---------RRVYGGAIGYFSITGYADFAIAIR--MAEIEGRK 397
APK ++++ + +S+ R VY G GY+S+ D+++ IR + G
Sbjct: 694 APKKITVQLLQDKIESKLNKHVNGGARGVYSGVTGYWSVNSNGDWSVNIRCMYSYNGGTS 753
Query: 398 AHVRAGAGIVADSIPEKEFYETENKMKAVLKAF 430
+ AG I S + E E NK+++ L+ F
Sbjct: 754 WQLGAGGAITVLSTLDGELEEMYNKLESNLQIF 786
>sp|P37254|PABS_YEAST PARA-AMINOBENZOATE SYNTHASE (P-AMINOBENZOIC ACID SYNTHASE) (PABA
SYNTHASE)
Length = 788
Score = 104 bits (257), Expect = 2e-21
Identities = 96/394 (24%), Positives = 185/394 (46%), Gaps = 55/394 (13%)
Query: 87 FLGGFMGYIAYDAVHNYI--------EGSIEEPSVFGYYPWVFIYNHGKGEL-------R 131
F+GG +G + Y+ + YI E S+ + + + NH +G+L
Sbjct: 399 FIGGLVGILGYE-IGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLYCISLDNT 457
Query: 132 FYYLRDPSFDPETIVERAKREEL---KFENGGAEIIRTDANREEFMEMVEKGKEYIFAGD 188
F + S + ++ ++ L K+ + I T ++ ++ + +K ++Y+ GD
Sbjct: 458 FPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKKCQDYMHKGD 517
Query: 189 VFQVVLSRE--YVLRSDVDPVELYRKLISINPSPYTFILEFKKIL------------VGA 234
+++ L+ + V + ++P +++ L+ NP+P++ EFK I+ +
Sbjct: 518 SYEMCLTTQTKVVPSAVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQDETPPVLCFLST 577
Query: 235 SPETMGSVEGRT-VRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDV 293
SPE + V +T ++ PI GT +G P+ + R+L KE E++M++DL RND+
Sbjct: 578 SPEKVFEVGMQTHAKLRPIKGTVKKG--PQMNLAKATRILKTPKEFGENLMILDLIRNDL 635
Query: 294 RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGE---LADDKDMF---DAIEASFPAGTLT 347
++ V++ F V +Y+ V + S V A K + D ++ S P G++T
Sbjct: 636 YELVP--DVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVLKHSLPPGSMT 693
Query: 348 GAPKIRAMEIIDELEKSR---------RRVYGGAIGYFSITGYADFAIAIR--MAEIEGR 396
GAPK ++++ + +S+ R VY G GY+S+ D+++ IR + G
Sbjct: 694 GAPKKITVQLLQDKIESKLNKHVNGGARGVYSGVTGYWSVNSNGDWSVNIRCMYSYNGGT 753
Query: 397 KAHVRAGAGIVADSIPEKEFYETENKMKAVLKAF 430
+ AG I S + E E NK+++ L+ F
Sbjct: 754 SWQLGAGGAITVLSTLDGELEEMYNKLESNLQIF 787
>gb|AAB49319.1| (U43608) Abz1p [Saccharomyces cerevisiae]
Length = 789
Score = 103 bits (254), Expect = 4e-21
Identities = 97/395 (24%), Positives = 186/395 (46%), Gaps = 56/395 (14%)
Query: 87 FLGGFMGYIAYDAVHNYI--------EGSIEEPSVFGYYPWVFIYNHGKGEL-------R 131
F+GG +G + Y+ + YI E S+ + + + NH +G+L
Sbjct: 399 FIGGLVGILGYE-IGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLYCISLDNT 457
Query: 132 FYYLRDPSFDPETIVERAKREEL---KFENGGAEIIRTDANREEFMEMVEKGKEYIFAGD 188
F + S + ++ ++ L K+ + I T ++ ++ + +K ++Y+ GD
Sbjct: 458 FPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKKCQDYMHKGD 517
Query: 189 VFQVVLSRE--YVLRSDVDPVELYRKLISINPSPYTFILEFKKIL------------VGA 234
+++ L+ + V + ++P +++ L+ NP+P++ EFK I+ +
Sbjct: 518 SYEMCLTTQTKVVPSAVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQDETPPVLCFLST 577
Query: 235 SPETMGSVEGRT-VRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDV 293
SPE + V +T ++ PI GT +G P+ + R+L KE E++M++DL RND+
Sbjct: 578 SPEKVFEVGMQTHAKLRPIKGTVKKG--PQMNLAKATRILKTPKEFGENLMILDLIRNDL 635
Query: 294 RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGE---LADDKDMF---DAIEASFPAGTLT 347
++ V++ F V +Y+ V + S V A K + D ++ S P G++T
Sbjct: 636 YELVP--DVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVLKHSLPPGSMT 693
Query: 348 GAPKIRAMEII-DELEK---------SRRRVYGGAIGYFSITGYADFAIAIR--MAEIEG 395
GAPK ++++ D++E +R VY G GY+S+ D+++ IR + G
Sbjct: 694 GAPKKITVQLLQDKIESKLNKHVNGGARGLVYSGVTGYWSVNSNGDWSVNIRCMYSYNGG 753
Query: 396 RKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAF 430
+ AG I S + E E NK+++ L+ F
Sbjct: 754 TSWQLGAGGAITVLSTLDGELEEMYNKLESNLQIF 788
>pir||A40365 siderophore biosynthetic protein amoA - Aeromonas hydrophila
Length = 396
Score = 102 bits (252), Expect = 8e-21
Identities = 76/270 (28%), Positives = 129/270 (47%), Gaps = 15/270 (5%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVL--RSDVDPVELYRKLISINPSPYTFILEFK- 228
EF V + G + +VVLSR+ L DP ++ +L++ NP + F L
Sbjct: 127 EFQASVSAALDAFAQGRLAKVVLSRKLTLTLHQPADPTQVMARLMAQNPHAFHFSLPLGQ 186
Query: 229 -KILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVD 287
+ L+GASPE + V V +P+A +A R P +++ + R LL+ K++ EH +++D
Sbjct: 187 GRRLLGASPELLLRVSEGEVFTHPLARSARRASEPAQEQMVARDLLASRKDQHEHKLVID 246
Query: 288 LARNDV----RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF-P 342
R + R+++ P S L+ + H+ + + G L + ++ P
Sbjct: 247 EIRRVLTPHCRELAIPSSPSLM------STDTLWHLGTPIAGRLNGGEASVLSLACQLHP 300
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
L G P A + I E E RR ++ G +G+ G ++A+ IR ++G + + A
Sbjct: 301 TPALCGYPTELARQFIREQEPFRRALFSGIVGWCDSQGNGEWAVVIRCGVLDGHQVELFA 360
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKAFGV 432
GAGIVA S P K+ +LKA G+
Sbjct: 361 GAGIVAGSDPPWSGPRPGTKLGTMLKALGL 390
>sp|P23300|AMOA_AERHY PUTATIVE ISOCHORISMATE SYNTHASE (AMONABACTIN)
>gi|141868|gb|AAA21935.1| (M63339) amonabactin
[Aeromonas hydrophila]
Length = 396
Score = 102 bits (252), Expect = 8e-21
Identities = 76/270 (28%), Positives = 129/270 (47%), Gaps = 15/270 (5%)
Query: 172 EFMEMVEKGKEYIFAGDVFQVVLSREYVL--RSDVDPVELYRKLISINPSPYTFILEFK- 228
EF V + G + +VVLSR+ L DP ++ +L++ NP + F L
Sbjct: 127 EFQASVSAALDAFAQGRLAKVVLSRKLTLTLHQPADPTQVMARLMAQNPHAFHFSLPLGQ 186
Query: 229 -KILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVD 287
+ L+GASPE + V V +P+A +A R P +++ + R LL+ K++ EH +++D
Sbjct: 187 GRRLLGASPELLLRVSEGEVFTHPLARSARRASEPAQEQMVARDLLASRKDQHEHKLVID 246
Query: 288 LARNDV----RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEASF-P 342
R + R+++ P S L+ + H+ + + G L + ++ P
Sbjct: 247 EIRRVLTPHCRELAIPSSPSLM------STDTLWHLGTPIAGRLNGGEASVLSLACQLHP 300
Query: 343 AGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRA 402
L G P A + I E E RR ++ G +G+ G ++A+ IR ++G + + A
Sbjct: 301 TPALCGYPTELARQFIREQEPFRRALFSGIVGWCDSQGNGEWAVVIRCGVLDGHQVELFA 360
Query: 403 GAGIVADSIPEKEFYETENKMKAVLKAFGV 432
GAGIVA S P K+ +LKA G+
Sbjct: 361 GAGIVAGSDPPWSGPRPGTKLGTMLKALGL 390
>emb|CAA70528.1| (Y09356) isochorismate synthase [Pseudomonas fluorescens]
Length = 391
Score = 101 bits (250), Expect = 1e-20
Identities = 78/271 (28%), Positives = 126/271 (45%), Gaps = 11/271 (4%)
Query: 169 NREEFMEMVEKGKEYIFAGDVFQVVLS--REYVLRSDVDPVELYRKLISINPSPYTFILE 226
+ + F VE DV + VLS RE + +DVD L L + NPS Y F +
Sbjct: 123 DEQAFKRAVEHAVVNFRHSDVRKAVLSVQRELIFANDVDVSALQHNLKAQNPSGYHFRVP 182
Query: 227 FKK--ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVM 284
L+G SPE + EG + NP+AG+A R PE D LL+ EK+ EH
Sbjct: 183 MPDGTTLIGVSPELLVRKEGLSSLSNPLAGSAKRMADPEADRRNADWLLTSEKDHYEHGF 242
Query: 285 LVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGELADDKDMFDAIEAS---F 341
+ + + K+ + + + +I + H+ + + G LAD A++ +
Sbjct: 243 VTQDIVSQLGKLCT--QLNVPQRPSLISTPALWHLSTRIEGTLADPA--VSALQLACRLH 298
Query: 342 PAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVR 401
P + G P RA +I +E R ++ G +G+ G ++ + IR + K +
Sbjct: 299 PTPAVCGFPTERARRLIRFVEPFERGLFTGMVGWCDAQGNGEWVVTIRCGTVRRNKVRLF 358
Query: 402 AGAGIVADSIPEKEFYETENKMKAVLKAFGV 432
AGAGIV S P+ E+ E + K+ +L+A G+
Sbjct: 359 AGAGIVEASSPDSEWAEVQTKLGTMLRACGL 389
>sp|P44613|MENF_HAEIN MENAQUINONE-SPECIFIC ISOCHORISMATE SYNTHASE >gi|1074943|pir||E64059
probable isochorismate synthase (EC 5.4.99.6) -
Haemophilus influenzae (strain Rd KW20)
>gi|1573249|gb|AAC21947.1| (U32714) menaquinone-specific
isochorismate synthase (menF) [Haemophilus influenzae
Rd]
Length = 430
Score = 99.8 bits (245), Expect = 5e-20
Identities = 83/322 (25%), Positives = 151/322 (46%), Gaps = 14/322 (4%)
Query: 118 PWVFIYNHGKGELRFYYLRDPSFDPETIVERAKREELKFENGGAEII----RTDANREEF 173
P + + KG L +++++ +T+ E L + + I AN +
Sbjct: 110 PKMLVEQDNKGTLVSFFVKNEQSANDTLAHLKTFENLTALSALPKQIPLHTELRANERTW 169
Query: 174 MEMVEKGKEYIFAGDVFQVVLSRE--YVLRSDVDPVELYRKLISINPSPYTFIL--EFKK 229
+ V + I +G++ ++VL+ E + L+ ++ + + N Y F+
Sbjct: 170 CDWVNQALVEIKSGELTKIVLANETTFHLKQAINAYDFLAESEKQNQGCYHFLWAENSHS 229
Query: 230 ILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLA 289
+ VG++PE + + E + +AGTA ++ EE + LL+DEK E+ ++V+
Sbjct: 230 VFVGSTPERLFAREYNLLLTEALAGTASVSESEEETQSQANWLLNDEKNLKENWLVVEDI 289
Query: 290 RNDVRKVSKPGSVKLVRFFDVIKYSH-VQHIESEVIGELADDKDMFDAIEASFPAGTLTG 348
++RK + V V + K H ++ I + + AD + ++A P ++G
Sbjct: 290 SQNLRKQVESFDVSNVELKPLRKVQHLIRKIRANLTAHYAD----VNILKAIHPTAAVSG 345
Query: 349 APKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRMAEIEGRKAHVRAGAGIVA 408
P+ +A I+ E+E R Y G +G S ++F +AIR A IEG + V AGAGIVA
Sbjct: 346 LPQQQAKMILSEIETFDRGWYAGTLGVMSDV-CSEFCVAIRSAFIEGHRIRVFAGAGIVA 404
Query: 409 DSIPEKEFYETENKMKAVLKAF 430
S P +E+ E E K ++ F
Sbjct: 405 GSQPLEEWKEIERKAAGLISLF 426
>gi|7705929 neutral sphingomyelinase [Homo sapiens] >gi|6606080|gb|AAF19052.1|
(AF069740) neutral sphingomyelinase [Homo sapiens]
Length = 398
Score = 98.3 bits (241), Expect = 2e-19
Identities = 69/252 (27%), Positives = 128/252 (50%), Gaps = 11/252 (4%)
Query: 191 QVVLSREYVLRSDVDPVELYRKLISINPSPYTFILEFKK---ILVGASPETMGSVEGRTV 247
+VV R+ L+ D + L + + ++ T+ + K+ + + A+PE + ++ G +
Sbjct: 150 KVVFGRQQTLQLS-DTLRLAQIIRALAEQANTYHVVLKRHDELFISATPERLVAMSGGQI 208
Query: 248 RINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRF 307
+AGT+ RG +D + LL+ +K R EH +V ++ V+ S+K+
Sbjct: 209 ATAAVAGTSRRGTDGADDIALGEALLASQKNRIEHQYVVASITTRLQDVTT--SLKVPAM 266
Query: 308 FDVIKYSHVQHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRR 367
++K VQH+ + + G++A + ++ P L G P+ A+ I EK+ R
Sbjct: 267 PSLLKNKQVQHLYTPITGDIAAHLSVTAIVDRLHPTPALGGVPREAALYYIATHEKTPRG 326
Query: 368 VYGGAIGYFSITGYADFAIAIRMAEIE--GRKAHVRAGAGIVADSIPEKEFYETENK--- 422
++ G IGYF+ +F + IR + R+A + AGAGIVADS ++E+ ET K
Sbjct: 327 LFAGPIGYFTADNSGEFVVGIRSMYVNQTQRRATLFAGAGIVADSDAQQEYEETGLKFEP 386
Query: 423 MKAVLKAFGVIQ 434
M+ +LK + ++
Sbjct: 387 MRQLLKDYNHVE 398
>gb|AAF80595.1|AF238500_1 (AF238500) isochorismate synthase [Azotobacter vinelandii]
Length = 361
Score = 96.0 bits (235), Expect = 8e-19
Identities = 69/243 (28%), Positives = 112/243 (45%), Gaps = 14/243 (5%)
Query: 159 GGAEIIRTDANREE-----FMEMVEKGKEYIFAGDVFQVVLSREYVLRSDVDPVELYRKL 213
GG +RT A R E + + V + E I G + +VVLSR +++++D EL + L
Sbjct: 112 GGPRPVRTVAARSEPAEAVYEQNVSRALERIADGKLQKVVLSRSLHIQAELDQAELLQTL 171
Query: 214 ISINPSPYTFILEF------KKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEE 267
S NP YT+ + ++ L+GASPE + + G V NP+AG+ P P ED +
Sbjct: 172 ASRNPLGYTYAIPLPTANGERRSLIGASPELLLARHGNRVISNPLAGSIPHSSDPAEDRQ 231
Query: 268 IRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGEL 327
LL K+ EH ++V+ +R + + ++ + H+ +EV G L
Sbjct: 232 RAENLLRSPKDLHEHALVVEAVAEALRPYCT--DLLVPEAPSLLSTPTMWHLSTEVTGTL 289
Query: 328 ADD-KDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAI 386
D + A P + G P A E I E R + G +G+ + G ++A+
Sbjct: 290 RDPATTSLELALALHPTPAVGGYPTAEAREFIQAFEGFDRGFFTGLVGWCNAQGDGEWAV 349
Query: 387 AIR 389
IR
Sbjct: 350 TIR 352
>sp|Q51508|PCHA_PSEAE SALICYLATE BIOSYNTHESIS ISOCHORISMATE SYNTHASE
>gi|2120630|pir||S58229 pchA protein - Pseudomonas
aeruginosa >gi|11352537|pir||B83117 salicylate
biosynthesis isochorismate synthase PA4231 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|929780|emb|CAA57969.1| (X82644) pchA [Pseudomonas
aeruginosa] >gi|9950447|gb|AAG07619.1|AE004840_5
(AE004840) salicylate biosynthesis isochorismate
synthase [Pseudomonas aeruginosa]
Length = 476
Score = 95.6 bits (234), Expect = 1e-18
Identities = 74/283 (26%), Positives = 125/283 (44%), Gaps = 18/283 (6%)
Query: 160 GAEIIRTDANREEFMEMVEKGKEYIFAGDVFQVVLSREYVLR-SDVDPVELYRKLISINP 218
GA+ + R ++ V + G +VVL+R D++P ++ L +
Sbjct: 190 GAQGDASAQERRQWEAKVSDAVSSVRQGRFGKVVLARTQARPLGDIEPWQVIEHLRLQHA 249
Query: 219 SPYTFILEF-KKILVGASPETMGSVEGRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEK 277
F +GASPE + + + +AGT RG +ED + + LL K
Sbjct: 250 DAQLFACRRGNACFLGASPERLVRIRAGEALTHALAGTIARGGDAQEDARLGQALLDSAK 309
Query: 278 ERAEHVMLVDLARNDVRKVSK-------PGSVKLVRFFDVIKYSHVQHIESEVIGELADD 330
+R EH ++V+ R + S+ PG +L R VQH+ + + LAD
Sbjct: 310 DRHEHQLVVEAIRTALEPFSEVLEIPDAPGLKRLAR---------VQHLNTPIRARLADA 360
Query: 331 KDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITGYADFAIAIRM 390
+ ++A P + G P+ A++ I + E R Y +G+ G DF +A+R
Sbjct: 361 GGILRLLQALHPTPAVGGYPRSAALDYIRQHEGMDRGWYAAPLGWLDGEGNGDFLVALRS 420
Query: 391 AEIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFGVI 433
A + + ++ AG G+V DS P E+ ET K+ A+ +A I
Sbjct: 421 ALLTPGRGYLFAGCGLVGDSEPAHEYRETCLKLSAMREALSAI 463
>gb|AAD31929.1|AF149719_1 (AF149719) para aminobenzoic acid synthetase [Aspergillus
fumigatus]
Length = 824
Score = 89.3 bits (218), Expect = 7e-17
Identities = 74/296 (25%), Positives = 136/296 (45%), Gaps = 37/296 (12%)
Query: 170 REEFMEMVEKGKEYIFAGDVFQVVLSREYV--LRSDVD-------PVELYRKLISINPSP 220
+E + + + + AG+ +++ L+ E + L S V P ELY++L NP+
Sbjct: 526 QENYQRQIRACQAELEAGESYELCLTGETLITLPSPVSQSGRASFPWELYKRLRKYNPAA 585
Query: 221 YTFILEFKKI-LVGASPETMGSVE-GRTVRINPIAGTAPRGKTPEEDEEIRRRLLSDEKE 278
++ + + +SPE + + T+ + P+ GT KT + E R +L KE
Sbjct: 586 FSGFARLGHVKIASSSPECFLNWDRDSTLEMKPMKGTVR--KTEDMTMEKAREILGSTKE 643
Query: 279 RAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIK----YSHVQHIESEVI----GELADD 330
AE++M+ DL R+D+ + G V + + +V Y + H++++V G A D
Sbjct: 644 MAENLMIADLIRHDLYGICGSGGVHVEKLLEVEDHGRVYQMITHVKAKVDRSRPGFAARD 703
Query: 331 KDMFD----------AIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSITG 380
A++ P G++TGAPK R+ + +E +R +Y G +G+ + G
Sbjct: 704 MPQLPSSNMSGYGLTALQRCLPPGSMTGAPKERSCMHLSSIEDRKRGIYSGVMGFLDLGG 763
Query: 381 YADFAIAIRMA------EIEGRKAHVRAGAGIVADSIPEKEFYETENKMKAVLKAF 430
F++ IR A + + + + AG + S PE E+ E K++ V F
Sbjct: 764 GGSFSVLIRTAFTCSNEQDDEQLWRIGAGGAVTTLSTPEGEWDEMLTKLRTVCGIF 819
>pir||T03800 anthranilate synthase - Streptomyces violaceus
>gi|2318113|gb|AAC35404.1| (AF012627) anthranilate
synthase [Streptomyces venezuelae]
Length = 623
Score = 85.4 bits (208), Expect = 1e-15
Identities = 90/302 (29%), Positives = 136/302 (44%), Gaps = 27/302 (8%)
Query: 146 VERAKREELKFENGGAEIIRTDANREEFMEMVEKG-KEYIFAGDVFQVVLSREYVLR--- 201
++R ++ E+GG D + EE+ +V + E I +G+ V+ R Y
Sbjct: 92 LDRLPAHDVTVEDGGF-----DVSDEEYAGIVRRVIDEEIGSGEGANFVIRRTYTGEIPG 146
Query: 202 -SDVDPVELYRKLISINPSPY-TFILEF-KKILVGASPETMGSVEGRTVRINPIAGT--A 256
D + L+R+L++ Y TF++ + LVGASPE + G TV +NPI+GT
Sbjct: 147 FGRADALALFRRLLAGERGAYWTFVVHTGDRTLVGASPEVHVRMSGGTVVMNPISGTYRY 206
Query: 257 PRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHV 316
P G P + + L+D KE E M+VD + V G V + + + +H+
Sbjct: 207 PAGAAPTAEGLL--AFLADRKETEELSMVVDEELKMMCTVGDMGGVVIGP--RLKEMAHL 262
Query: 317 QHIESEVIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYF 376
H E E+ G D+ + + + A T+TG+P A +I+ E R Y GA+
Sbjct: 263 AHTEYELRGR--SSLDVREVLRETMFAATVTGSPVQNACRVIERHEVGGRGYYAGALALL 320
Query: 377 SI----TGYADFAIAIRMAEIEGRKAHVR--AGAGIVADSIPEKEFYETENKMKAVLKAF 430
D I IR A+I H+R GA +V S P E ET K VL A
Sbjct: 321 GTDENGAQSLDSPILIRTADI-AADGHLRVPVGATLVRHSDPAGEVAETHAKAAGVLTAL 379
Query: 431 GV 432
GV
Sbjct: 380 GV 381
>pir||T35498 probable anthranilate synthase - Streptomyces coelicolor
>gi|5689927|emb|CAB51965.1| (AL109661) putative
anthranilate synthase [Streptomyces coelicolor A3(2)]
Length = 634
Score = 81.9 bits (199), Expect = 1e-14
Identities = 92/301 (30%), Positives = 132/301 (43%), Gaps = 34/301 (11%)
Query: 153 ELKFENGGAEIIRTDANREEFMEMVEKG-KEYIFAGDVFQVVLSREYVLR----SDVDPV 207
E++ E GG D EE+ +V + E I G+ V+ R Y R D +
Sbjct: 96 EVRVEGGGF-----DVGDEEYARIVGRVLDEEIGRGEGANFVIRRTYEGRIPGFGRADAL 150
Query: 208 ELYRKLISINPSPY-TFILEF-KKILVGASPETMGSVEGRTVRINPIAGT---APRGKTP 262
L+R+L++ Y TF++ + LVGASPE + G TV +NPI+GT G TP
Sbjct: 151 ALFRRLLAGERGAYWTFVVHTGDRTLVGASPEVHVRMSGGTVVMNPISGTYRYPAEGPTP 210
Query: 263 EEDEEIRRRLLSDEKERAEHVMLVDLARNDVRKVSKPGSVKLVRFFDVIKYSHVQHIESE 322
E + L+D KE E M+VD + V G V V + + +H+ H E E
Sbjct: 211 EHLLD----FLADGKEIEELSMVVDEELKMMCTVGDMGGV--VVGPRLKEMAHLAHTEYE 264
Query: 323 VIGELADDKDMFDAIEASFPAGTLTGAPKIRAMEIIDELEKSRRRVYGGAIGYFSI---- 378
+ G+ D + + + A T+TG+P A +I+ E R Y GA+
Sbjct: 265 LRGK--SSLDAREVLRETMFAATVTGSPVQNACRVIERHETGGRGYYAGALALLGRDPGD 322
Query: 379 ------TGYADFAIAIRMAEIEGR-KAHVRAGAGIVADSIPEKEFYETENKMKAVLKAFG 431
D I IR A+I+ + V GA +V S P E ET K VL A G
Sbjct: 323 GPGQPGPQTLDSPILIRTADIDAAGRLRVPVGATLVRGSDPAGEVAETHAKAAGVLAALG 382
Query: 432 V 432
V
Sbjct: 383 V 383
>gb|AAA34840.1| (L15299) para-aminobenzoate synthase [Saccharomyces cerevisiae]
Length = 733
Score = 78.4 bits (190), Expect = 1e-13
Identities = 74/318 (23%), Positives = 150/318 (46%), Gaps = 44/318 (13%)
Query: 87 FLGGFMGYIAYDAVHNYI--------EGSIEEPSVFGYYPWVFIYNHGKGEL-------R 131
F+GG +G + Y+ + YI E S+ + + + NH +G+L
Sbjct: 399 FIGGLVGILGYE-IGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLYCISLDNT 457
Query: 132 FYYLRDPSFDPETIVERAKREEL---KFENGGAEIIRTDANREEFMEMVEKGKEYIFAGD 188
F + S + ++ ++ L K+ + I T ++ ++ + +K ++Y+ GD
Sbjct: 458 FPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKKCQDYMHKGD 517
Query: 189 VFQVVLSRE--YVLRSDVDPVELYRKLISINPSPYTFILEFKKIL------------VGA 234
+++ L+ + V + ++P +++ L+ NP+P++ EFK I+ +
Sbjct: 518 SYEMCLTTQTKVVPSTVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQDETPPVLCFLST 577
Query: 235 SPETMGSVEGRT-VRINPIAGTAPRGKTPEEDEEIRRRLLSDEKERAEHVMLVDLARNDV 293
SP + V +T + PI GT +G P+ + R+L KE E++M++DL RND+
Sbjct: 578 SPVKVFEVGMQTHSLLRPIKGTVKKG--PQMNLAKATRILKTPKEFGENLMILDLIRNDL 635
Query: 294 RKVSKPGSVKLVRFFDVIKYSHVQHIESEVIGE---LADDKDMF---DAIEASFPAGTLT 347
++ V++ F V +Y+ V + S V A K + D ++ S P G++T
Sbjct: 636 YELVP--DVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVLKHSLPPGSMT 693
Query: 348 GAPKIRAMEIIDELEKSR 365
GAPK ++++ + +S+
Sbjct: 694 GAPKKITVQLLQDKIESK 711
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.139 0.389
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 164778898
Number of Sequences: 2977
Number of extensions: 7426086
Number of successful extensions: 19331
Number of sequences better than 1.0e-10: 185
Number of HSP's better than 0.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 18775
Number of HSP's gapped (non-prelim): 228
length of query: 434
length of database: 189,106,746
effective HSP length: 58
effective length of query: 376
effective length of database: 154,394,500
effective search space: 58052332000
effective search space used: 58052332000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)