BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2047 (trpF) DE:phosphoribosyl anthranilate isomerase (trpF) (208 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||G75162 phosphoribosyl anthranilate isomerase (trpf) PAB2047... 407 e-113 sp|Q9YGB1|TRPF_PYRKO N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 256 2e-67 gi|11499194 phosphoribosyl anthranilate isomerase (trpF) [Archae... 203 2e-51 sp|O67853|TRPF_AQUAE N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 94 2e-18 sp|P52563|TRPF_HALVO N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 92 6e-18 sp|Q56320|TRPF_THEMA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 91 1e-17 pdb|1DL3|A Chain A, Crystal Structure Of Mutually Generated Mono... 89 3e-17 sp|Q57893|TRPF_METJA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 86 3e-16 sp|P20409|TRPG_PHYBL ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 85 8e-16 gb|AAA33633.1| (M23177) trifunctional protein with glutamine ami... 85 8e-16 gb|AAG19903.1| (AE005074) phosphoribosylanthranilate isomerase; ... 82 4e-15 sp|P17218|TRPF_LACCA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 80 3e-14 sp|P00908|TRPG_NEUCR ANTHRANILATE SYNTHASE COMPONENT II [INCLUDE... 76 3e-13 gi|6320210 n-(5'-phosphoribosyl)-anthranilate isomerase; Trp1p [... 74 1e-12 gb|AAA72099.1| (M74016) putative. start [Cloning vector pYADE4] ... 74 1e-12 gb|AAA87582.1| (U46126) chloramphenicol resistance protein [synt... 74 1e-12 sp|P13997|TRPF_KLULA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 73 2e-12 sp|P00912|TRPF_YEAST N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 73 3e-12 sp|P24920|TRPC_PHYPR TRYPTOPHAN BIOSYNTHESIS PROTEIN TRP1 [INCLU... 71 1e-11 sp|Q59649|TRPF_PSEAE N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 69 3e-11 sp|P16923|TRPF_ACICA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE... 69 4e-11 >pir||G75162 phosphoribosyl anthranilate isomerase (trpf) PAB2047 - Pyrococcus abyssi (strain Orsay) >gi|5457892|emb|CAB49382.1| (AJ248284) phosphoribosyl anthranilate isomerase (trpF) [Pyrococcus abyssi] Length = 208 Score = 407 bits (1034), Expect = e-113 Identities = 208/208 (100%), Positives = 208/208 (100%) Query: 1 MFVKVCGVKSLEELEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKN 60 MFVKVCGVKSLEELEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKN Sbjct: 1 MFVKVCGVKSLEELEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKN 60 Query: 61 REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLLK 120 REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLLK Sbjct: 61 REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLLK 120 Query: 121 KIRKYEADLILLDTGAGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVKPFGVD 180 KIRKYEADLILLDTGAGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVKPFGVD Sbjct: 121 KIRKYEADLILLDTGAGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVKPFGVD 180 Query: 181 VSSGVERNGKKDEELVREFVRRAKNVVR 208 VSSGVERNGKKDEELVREFVRRAKNVVR Sbjct: 181 VSSGVERNGKKDEELVREFVRRAKNVVR 208 >sp|Q9YGB1|TRPF_PYRKO N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|11268651|pir||T43926 phosphoribosylanthranilate isomerase (EC 5.3.1.24) [imported] - Pyrococcus kodakaraensis >gi|5545308|dbj|BAA82549.1| (AB030011) phosphoribosyl anthranilate isomerase [Thermococcus kodakaraensis] Length = 208 Score = 256 bits (646), Expect = 2e-67 Identities = 123/204 (60%), Positives = 157/204 (76%) Query: 2 FVKVCGVKSLEELEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKNR 61 FVK+CGVK+++EL +VE+YADATGVVVNS+SKR VPL A E+I A+IP++LVSTMK Sbjct: 4 FVKICGVKTMDELRLVERYADATGVVVNSRSKRKVPLKTAAELIEMAEIPIYLVSTMKTF 63 Query: 62 EDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLLKK 121 +W A+E+T A YIQ+HSD+ P + LKDEYGV +MKAF VP+ES++P DA+ LL+ Sbjct: 64 PEWANAVEKTGAEYIQVHSDMHPKAVNRLKDEYGVSVMKAFMVPRESDDPAEDAERLLEL 123 Query: 122 IRKYEADLILLDTGAGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVKPFGVDV 181 I +YE D ILLDTG GSG+ HD RV+ I+A+E P+V+AGGL PENV I+ VKP GVDV Sbjct: 124 IGQYEVDKILLDTGVGSGRRHDYRVSAIIAKEYPIVLAGGLTPENVGEAIRWVKPAGVDV 183 Query: 182 SSGVERNGKKDEELVREFVRRAKN 205 SSGVERNG KD L+ F+ +N Sbjct: 184 SSGVERNGVKDRVLIEAFMAVVRN 207 >gi|11499194 phosphoribosyl anthranilate isomerase (trpF) [Archaeoglobus fulgidus] >gi|3334395|sp|O28671|TRPF_ARCFU N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|7436788|pir||H69449 phosphoribosyl anthranilate isomerase (trpF) homolog - Archaeoglobus fulgidus >gi|2648959|gb|AAB89648.1| (AE000992) phosphoribosyl anthranilate isomerase (trpF) [Archaeoglobus fulgidus] Length = 199 Score = 203 bits (510), Expect = 2e-51 Identities = 113/208 (54%), Positives = 140/208 (66%), Gaps = 9/208 (4%) Query: 1 MFVKVCGVKSLEELEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKN 60 M VKVCGVKSL+EL+ VE+YAD TGVVV S SKR V LD A+E+I S+ IPVF VST + Sbjct: 1 MMVKVCGVKSLKELDAVERYADFTGVVVKSDSKRCVELDVAKELIGSSSIPVFAVSTASS 60 Query: 61 REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLLK 120 +WE + +TE + Q+HS++ LK E V++MKAF V E A+ + Sbjct: 61 YAEWEEILAKTECSFAQVHSEMPLEDFERLKAE--VKVMKAFIV-------EGPAEKIAA 111 Query: 121 KIRKYEADLILLDTGAGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVKPFGVD 180 KI Y LILLD+G GSGK HD V++ +AE V +AGGL +NV I+ V+P GVD Sbjct: 112 KIELYSPHLILLDSGCGSGKTHDWNVSKALAERYGVFLAGGLNLDNVREAIRFVRPMGVD 171 Query: 181 VSSGVERNGKKDEELVREFVRRAKNVVR 208 VSSGVER+G KDE LVREFVRRAKN VR Sbjct: 172 VSSGVERDGLKDEMLVREFVRRAKNEVR 199 >sp|O67853|TRPF_AQUAE N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|7436783|pir||A70478 phosphoribosylanthranilate isomerase (EC 5.3.1.24) - Aquifex aeolicus >gi|2984287|gb|AAC07811.1| (AE000771) phosphoribosyl anthranilate isomerase [Aquifex aeolicus] Length = 204 Score = 93.6 bits (229), Expect = 2e-18 Identities = 78/216 (36%), Positives = 121/216 (55%), Gaps = 29/216 (13%) Query: 3 VKVCGVKSLEE-LEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAK-IPVFLVSTMKN 60 VK+CG+ +LE+ L ++ AD GV+ KS R + EII + + + V V+ + N Sbjct: 4 VKICGITNLEDALFCAKEGADYIGVITYPKSPRYTSKEKRLEIIKALEGLNVKKVAVVVN 63 Query: 61 REDWEVAIERTEARY--IQIHSDVEPSLLPYLKDEYGVE-IMKAFRVPQESENPERDAQM 117 E +E E + + IQ+H D + L G++ ++K FRV +E Sbjct: 64 -EPYEFIKELLDEGFDLIQLHGDEDIEL----GKRVGLDKVIKVFRVKEE---------- 108 Query: 118 LLKKIRKYE-ADLILLDTGA-----GSGKMHDLRVTRIVAEE-IPVVVAGGLKPENVEMV 170 + K+ ++E A ILLDT + G+GK + + + + EE V ++GGL PENV+ Sbjct: 109 -IPKVGEWEKAYAILLDTFSKEAYGGTGKTFNWEIAKKLVEEGHKVFLSGGLNPENVKEG 167 Query: 171 IKLVKPFGVDVSSGVER-NGKKDEELVREFVRRAKN 205 I+ VKP+GVDVSSGVE+ GKKD + VREF++R K+ Sbjct: 168 IEFVKPYGVDVSSGVEKEKGKKDFKKVREFIKRTKS 203 >sp|P52563|TRPF_HALVO N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|149038|gb|AAA73176.1| (M83788) N-phosphoribosyl anthranilate isomerase [Haloferax volcanii] Length = 221 Score = 91.7 bits (224), Expect = 6e-18 Identities = 76/214 (35%), Positives = 112/214 (51%), Gaps = 22/214 (10%) Query: 3 VKVCGVKSLEELEIVEKY-ADATGVV--VNSKSKRNVPLDAAREIISSAKIPVFLVSTMK 59 VKVCGV +L V+ ADA G + V + R +P + ARE+ ++A P FL +T+ Sbjct: 4 VKVCGVTDETDLAAVDAAGADAVGAICDVPVDTPREIPRERARELFAAA--PPFLTTTLV 61 Query: 60 NREDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLL 119 D V R AR +V P +L L ++ + + + R P DA L Sbjct: 62 TMPD-SVDHARDLAR------EVGPDVLQ-LHGDFAADDLDSLRATGVGVVPVVDATDLA 113 Query: 120 K-KIRKYEADLILLDT-----GAGSGKMHDLRVTR--IVAEEIPVVVAGGLKPENVEMVI 171 + + D IL+DT G+G+ HD +R + A + PV++AGGL P+NV + Sbjct: 114 RARDLAPVVDAILVDTPSDSGAGGTGETHDWDASRDLVAAVDAPVILAGGLTPDNVVEAV 173 Query: 172 KLVKPFGVDVSSGVERN-GKKDEELVREFVRRAK 204 + V+P+GVDV+SGVE + G KD + VR FV AK Sbjct: 174 RTVEPYGVDVASGVEASGGVKDHDAVRAFVAAAK 207 >sp|Q56320|TRPF_THEMA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|2120368|pir||S59048 phosphoribosylanthranilate isomerase (EC 5.3.1.24) trpF [validated] - Thermotoga maritima (strain MSB8) >gi|1941978|pdb|1NSJ| Crystal Structure Of Phosphoribosyl Anthranilate Isomerase From Thermotoga Maritima >gi|1054860|emb|CAA63390.1| (X92729) phosphoribosyl anthranilate isomerase [Thermotoga maritima] >gi|4980631|gb|AAD35232.1|AE001699_9 (AE001699) phosphoribosylanthranilate isomerase [Thermotoga maritima] Length = 205 Score = 90.9 bits (222), Expect = 1e-17 Identities = 73/215 (33%), Positives = 109/215 (49%), Gaps = 24/215 (11%) Query: 3 VKVCGVKSLEE-LEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIP--VFLVSTMK 59 VK+CG+ +LE+ L VE ADA G V KSKR + + AR I S ++P VF V Sbjct: 4 VKICGITNLEDALFSVESGADAVGFVFYPKSKRYISPEDARRI--SVELPPFVFRVGVFV 61 Query: 60 NREDWEV--AIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQM 117 N E ++ + +Q+H + L + + + ++KA V E + Sbjct: 62 NEEPEKILDVASYVQLNAVQLHGEEPIELCRKIAER--ILVIKAVGVSNERD-------- 111 Query: 118 LLKKIRKYEADLILLDTGA----GSGKMHDLRVTRIVAEEIP-VVVAGGLKPENVEMVIK 172 +++ Y ILLDT GSGK D + + +V++GGL PENV I Sbjct: 112 -MERALNYREFPILLDTKTPEYGGSGKTFDWSLILPYRDRFRYLVLSGGLNPENVRSAID 170 Query: 173 LVKPFGVDVSSGVER-NGKKDEELVREFVRRAKNV 206 +V+PF VDVSSGVE GKKD + ++ F++ AK + Sbjct: 171 VVRPFAVDVSSGVEAFPGKKDHDSIKMFIKNAKGL 205 >pdb|1DL3|A Chain A, Crystal Structure Of Mutually Generated Monomers Of Dimeric Phosphoribosylantranilate Isomerase From Thermotoga Maritim >gi|8569670|pdb|1DL3|B Chain B, Crystal Structure Of Mutually Generated Monomers Of Dimeric Phosphoribosylantranilate Isomerase From Thermotoga Maritim Length = 203 Score = 89.3 bits (218), Expect = 3e-17 Identities = 71/213 (33%), Positives = 106/213 (49%), Gaps = 22/213 (10%) Query: 3 VKVCGVKSLEE-LEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKNR 61 VK+CG+ +LE+ L VE AD G V KSKR + + AR I S ++PV V N Sbjct: 4 VKICGITNLEDALFSVESGADYVGFVFYPKSKRYISPEDARRI--SVELPVERVGVFVNE 61 Query: 62 EDWEV--AIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLL 119 E ++ + +Q+H + L + + + + KA V E + + Sbjct: 62 EPEKILDVASYVQLNAVQLHGEEPIELCRKIAER--ILVWKAVGVSNERD---------M 110 Query: 120 KKIRKYEADLILLDTGA----GSGKMHDLRVTRIVAEEIP-VVVAGGLKPENVEMVIKLV 174 ++ Y ILLDT GSGK D + + +V++GGL PENV I +V Sbjct: 111 ERALNYREFPILLDTKTPEYGGSGKTFDWSLILPYRDRFRYLVLSGGLNPENVRSAIDVV 170 Query: 175 KPFGVDVSSGVER-NGKKDEELVREFVRRAKNV 206 +PF VDVSSGVE GKKD + ++ F++ AK + Sbjct: 171 RPFAVDVSSGVEAFPGKKDHDSIKMFIKNAKGL 203 >sp|Q57893|TRPF_METJA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|2129198|pir||C64356 phosphoribosylanthranilate isomerase (EC 5.3.1.24) - Methanococcus jannaschii >gi|1591155|gb|AAB98440.1| (U67496) phosphoribosylanthranilate isomerase (trpF) [Methanococcus jannaschii] Length = 226 Score = 86.2 bits (210), Expect = 3e-16 Identities = 70/222 (31%), Positives = 109/222 (48%), Gaps = 21/222 (9%) Query: 3 VKVCGVKSLEELEIVEKYADATGVVVNS--KSKRNVPLDAAREIISSAKIPVFLVSTMKN 60 VK+CG+ + E++ + K A GV+V+ K+ R + LD A E+ LV+ + Sbjct: 8 VKICGITNEEDIAYISKKVHAVGVIVDVPVKTPRKISLDKAIELKKYVAPFTSLVTVLMP 67 Query: 61 REDWEVA--IERTEARYIQIHSDVEPSLLPYLKD-----EYGVEIMKAFRVPQESENPER 113 EV + IQ+H + L E I+K +P++ E Sbjct: 68 NSIEEVLEIYNALKPNAIQLHGFESLDFVKELNKLKNTGELNAHIIKVIHIPKDEEI--- 124 Query: 114 DAQMLLKKIRKYE--ADLILLDTGAGS----GKMHDLRVTRIVAEEI--PVVVAGGLKPE 165 D + LL ++YE + IL+DT S GK H+ V++ + E + P+++AGGL + Sbjct: 125 DFKTLLNTAKEYEKYVEAILVDTKIESIKLEGKTHNWAVSKKLRESLEKPLILAGGLNKD 184 Query: 166 NVEMVIKLVKPFGVDVSSGVER-NGKKDEELVREFVRRAKNV 206 NV IK VKP+ +DVSS +E GKKD + V EF+ K V Sbjct: 185 NVLEAIKTVKPYAIDVSSSLEAYGGKKDLKKVDEFLEVIKKV 226 >sp|P20409|TRPG_PHYBL ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI)] >gi|82774|pir||JT0383 anthranilate synthase (EC 4.1.3.27) component II - Phycomyces blakesleeanus Length = 765 Score = 84.7 bits (206), Expect = 8e-16 Identities = 71/258 (27%), Positives = 114/258 (43%), Gaps = 62/258 (24%) Query: 3 VKVCGVKSLEE-LEIVEKYADATGVVVNSKSKRNVPLDAAREIISSA-KIPV----FLVS 56 VK+CG+ S+E +E AD G++ KSKR V + AREI+ + K+P V Sbjct: 513 VKICGISSVEAAVEAATAGADLVGLIFAEKSKRQVTVAKAREIVDALHKLPTRSSQLPVK 572 Query: 57 TMKNREDWEVAIERTEARY-----------------------------IQIHSDVEPSLL 87 + K+ + ++V E E R IQ+H + Sbjct: 573 SQKSIDWFDVQTEMVEQRVPWRPLVVGVFVNQSIEYMSQVAVEAGLDLIQLHGTESAEIA 632 Query: 88 PYLKDEYGVEIMKAFRVPQES---------ENPERDAQMLLKKIRKYEADLILLDTGAGS 138 +L V ++KAF + S P + +LL + + +D G Sbjct: 633 RFLP----VPVIKAFHMDASSFHAGQIPYVTQPGNNQLLLLDA----KVPSLPMDRQGGL 684 Query: 139 GKMHDLRVTRIVA----------EEIPVVVAGGLKPENVEMVIKLVKPFGVDVSSGVERN 188 G+ D + + + + PV++AGGL P N+ I+ V+P+ VDVSSGVE + Sbjct: 685 GQKFDWTIAQDIVNVKRPGCSKEQTFPVILAGGLDPSNISEAIQQVRPWAVDVSSGVETD 744 Query: 189 GKKDEELVREFVRRAKNV 206 GKKD + +R FV +AK++ Sbjct: 745 GKKDLKKIRAFVEKAKSI 762 >gb|AAA33633.1| (M23177) trifunctional protein with glutamine amidotransferase (TrpG), phosphoribosylanthranilate isomerase (TrpF), and indoleglycerolphosphate synthetase (TrpC) activities [Phycomyces blakesleeanus] Length = 765 Score = 84.7 bits (206), Expect = 8e-16 Identities = 71/258 (27%), Positives = 114/258 (43%), Gaps = 62/258 (24%) Query: 3 VKVCGVKSLEE-LEIVEKYADATGVVVNSKSKRNVPLDAAREIISSA-KIPV----FLVS 56 VK+CG+ S+E +E AD G++ KSKR V + AREI+ + K+P V Sbjct: 513 VKICGISSVEAAVEAATAGADLVGLIFAEKSKRQVTVAKAREIVDALHKLPTRSSQLPVK 572 Query: 57 TMKNREDWEVAIERTEARY-----------------------------IQIHSDVEPSLL 87 + K+ + ++V E E R IQ+H + Sbjct: 573 SQKSIDWFDVQTEMVEQRVPWRPLVVGVFVNQSTEYMSQVAVEAALDLIQLHGTESAEIA 632 Query: 88 PYLKDEYGVEIMKAFRVPQES---------ENPERDAQMLLKKIRKYEADLILLDTGAGS 138 +L V ++KAF + S P + +LL + + +D G Sbjct: 633 RFLP----VPVIKAFHMDASSFHAGQIPYVTQPGNNQLLLLDA----KVPSLPMDRQGGL 684 Query: 139 GKMHDLRVTRIVA----------EEIPVVVAGGLKPENVEMVIKLVKPFGVDVSSGVERN 188 G+ D + + + + PV++AGGL P N+ I+ V+P+ VDVSSGVE + Sbjct: 685 GQKFDWTIAQDIVNVKRPGCSKEQTFPVILAGGLDPSNISEAIQQVRPWAVDVSSGVETD 744 Query: 189 GKKDEELVREFVRRAKNV 206 GKKD + +R FV +AK++ Sbjct: 745 GKKDLKKIRAFVEKAKSI 762 >gb|AAG19903.1| (AE005074) phosphoribosylanthranilate isomerase; TrpF [Halobacterium sp. NRC-1] Length = 218 Score = 82.3 bits (200), Expect = 4e-15 Identities = 72/223 (32%), Positives = 102/223 (45%), Gaps = 39/223 (17%) Query: 3 VKVCGVKS-LEELEIVEKYADATGVVVNSKSKRNVPLDAAREIISS------AKIPVFLV 55 VKVCG+ + + V ADA G++ + VP++ RE+ A P F+ Sbjct: 4 VKVCGLTTERDHAAAVAAGADAVGIIAD------VPVETPREVSVETATALRAATPPFVT 57 Query: 56 S---TMKNREDWEVAIERTEAR-YIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENP 111 S TM + V + RT A +Q+H D+ Y+ ++KA +S Sbjct: 58 SVLVTMPATPEHAVDLVRTVAPDAVQLHGDLPVGDAAYVAANTPCPVIKAVTAGDQSAAR 117 Query: 112 ERDAQMLLKKIRKYEADLILLDT--------GAGSGKMHDLRVTRIVAEEI--PVVVAGG 161 D D +L+D+ G G+G+ HD TR A+ + PVV+AGG Sbjct: 118 YADV-----------VDALLVDSPPTDDAGAGGGTGRTHDWAATRAFADRVDTPVVLAGG 166 Query: 162 LKPENVEMVIKLVKPFGVDVSSGVE-RNGKKDEELVREFVRRA 203 L P NV + V PF VDV+SGVE R G+KD V FV RA Sbjct: 167 LTPANVADAVDTVDPFAVDVASGVEARPGEKDHAAVSAFVARA 209 >sp|P17218|TRPF_LACCA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|80562|pir||JS0342 phosphoribosylanthranilate isomerase (EC 5.3.1.24) - Lactobacillus casei >gi|216758|dbj|BAA00385.1| (D00496) trpF protein [Lactobacillus casei] Length = 199 Score = 79.6 bits (193), Expect = 3e-14 Identities = 63/207 (30%), Positives = 108/207 (51%), Gaps = 21/207 (10%) Query: 1 MFVKVCGVKSLEELEIVEKY-ADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMK 59 + VK+CG+ E++ V AD G V + + V L+ A + + V Sbjct: 2 VLVKICGLMHSEDILAVNTAGADFAGFVF-APGRHQVSLEQALALNQLLHSKIKTVGVFV 60 Query: 60 NREDWEV-AIERTEARYI-QIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQM 117 N E+ AI + A + Q+H P+ + L+ + G+++++ F ER A Sbjct: 61 NEPVAEILAIYQAGAIDVAQLHGKSTPAEITQLQ-QAGLKVIQVF---------ERQAID 110 Query: 118 LLKKIRKYEADLILLDTGAGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVKPF 177 L AD +++D+G GSG++ +L+ ++ P+++AGGL P NV ++LV+P Sbjct: 111 LTSM-----ADYLMVDSGKGSGQLLNLKAIPHISR--PLILAGGLTPLNVRQAVQLVQPT 163 Query: 178 GVDVSSGVERNGKKDEELVREFVRRAK 204 VDVSSGVE NG KD + + +F+++AK Sbjct: 164 MVDVSSGVETNGHKDADKITQFIQQAK 190 >sp|P00908|TRPG_NEUCR ANTHRANILATE SYNTHASE COMPONENT II [INCLUDES: GLUTAMINE AMIDOTRANSFERASE; INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS); N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI)] >gi|68271|pir||NNNC2 anthranilate synthase (EC 4.1.3.27) component II - Neurospora crassa Length = 762 Score = 76.1 bits (184), Expect = 3e-13 Identities = 68/239 (28%), Positives = 117/239 (48%), Gaps = 40/239 (16%) Query: 1 MFVKVCGVKSLEEL-EIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMK 59 + VK+CG +S E E ++ AD G+++ +KR V + A I + V K Sbjct: 530 LLVKICGTRSAEAAAEAIKAGADLVGMIMVPGTKRCVDHETALSISQA-------VHMSK 582 Query: 60 NREDWEVAIERTEAR--YIQIHSDV----EPSLLPYLKDEYGVEIMKAFR------VPQE 107 EV+ + +++ + I++++ P L+ ++ E+++ V Sbjct: 583 KTGSTEVSSQASKSARDFFNINAEIIRKRGPLLVGVFMNQPLEEVLEKQHLYDLDIVQLH 642 Query: 108 SENPERDAQML-LKKIRKYEADLI-----------LLDTGAGSGKMHDLRVTRIVAE--- 152 + P A ++ + +RK++ + LLD+GAGSG + DL + E Sbjct: 643 GDEPLEWANLIPVPVVRKFKPGQVGLATRGYHAVPLLDSGAGSGTLLDLESVKKELEKDE 702 Query: 153 EIPVVVAGGLKPENVEMVIKLVKPF-----GVDVSSGVERNGKKDEELVREFVRRAKNV 206 ++ V++AGGL+P NV +K + P GVDVSSGVE GK+ E +REFV+ AK+V Sbjct: 703 QVTVLLAGGLEPSNVVETVKSLGPLSERVIGVDVSSGVEEGGKQSLEKIREFVKAAKSV 761 >gi|6320210 n-(5'-phosphoribosyl)-anthranilate isomerase; Trp1p [Saccharomyces cerevisiae] >gi|4668|emb|CAA24634.1| (V01341) trp1 [Saccharomyces cerevisiae] >gi|173017|gb|AAA72097.1| (M74015) putative [Cloning vector pYSVE2] >gi|173040|gb|AAA88758.1| (J01374) N-(5'-phosphoribosyl)-anthranilate isomerase [Saccharomyces cerevisiae] >gi|408372|gb|AAA67143.1| (U01086) N-(5'phosphoribosyl)anthranilate isomerase (TRP1) [synthetic construct] >gi|988209|gb|AAA96381.1| (U30497) TRP1 gene product [Cloning vector pAS2-1] >gi|1052965|gb|AAA80670.1| (U37456) N-(5'-phosphoribosyl)-anthranilate isomerase [Cloning vector YITAG100] >gi|1236520|gb|AAA92918.1| (U46855) TRP1 [Cloning vector pAS1-tet] >gi|1373272|gb|AAB02233.1| (U57443) Trp1p [Cloning vector pODB8] >gi|1595817|gb|AAB49941.1| (U70018) TRP1 [Cloning vector pGBD-C1] >gi|1595821|gb|AAB49944.1| (U70019) TRP1 [Cloning vector pGBD-C2] >gi|1595825|gb|AAB49947.1| (U70020) TRP1 [Cloning vector pGBD-C3] >gi|2267563|gb|AAB63578.1| (AF008932) TRP1 [DNA-binding vector pODB80] >gi|3243019|gb|AAC23874.1| (AF069720) phosphoribosylanthranilate isomerase [Expression vector pBEVY-GT] >gi|3243028|gb|AAC23880.1| (AF069723) phosphoribosylanthranilate isomerase [Expression vector pBEVY-T] >gi|6318569|gb|AAF06952.1| (AF134781) N-(5'-phosphoribosyl)-anthranilate isomerase [Cloning vector YEP46] >gi|6642843|gb|AAF20320.1| (AF134165) n-(5'-phosphoribosyl)-anthranilate isomerase [Yeast 2-hybrid vector pCD.1] >gi|6642846|gb|AAF20322.1| (AF134166) n-(5'-phosphoribosyl)-anthranilate isomerase [Yeast 2-hybrid vector pCD.2] >gi|11344896|gb|AAG34533.1| (AF298789) phosphoribosylanthranilate isomerase [recombinase expression vector pSH63] Length = 224 Score = 73.7 bits (178), Expect = 1e-12 Identities = 67/220 (30%), Positives = 101/220 (45%), Gaps = 28/220 (12%) Query: 3 VKVCGVKSLEELEI-VEKYADATGVVVNSKSKRNVPLDAAREIISSAKI-------PVFL 54 VKVCG++S E E ++ AD G++ KR + AR+I S K P +L Sbjct: 14 VKVCGLQSTEAAECALDSDADLLGIICVPNRKRTIDPVIARKISSLVKAYKNSSGTPKYL 73 Query: 55 VSTMKN--REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPE 112 V +N +ED + +Q+H D S Y ++ G+ ++K P Sbjct: 74 VGVFRNQPKEDVLALVNDYGIDIVQLHGD--ESWQEY-QEFLGLPVIKRLVFP------- 123 Query: 113 RDAQMLLKKI-RKYEADLILLDTGAGS-------GKMHDLRVTRIVAEEIPVVVAGGLKP 164 +D +LL +K + + L D+ AG + D + E + ++AGGL P Sbjct: 124 KDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSISDWVGRQESPESLHFMLAGGLTP 183 Query: 165 ENVEMVIKLVKPFGVDVSSGVERNGKKDEELVREFVRRAK 204 ENV ++L GVDVS GVE NG KD + FV+ AK Sbjct: 184 ENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANFVKNAK 223 >gb|AAA72099.1| (M74016) putative. start [Cloning vector pYADE4] >gi|1049260|gb|AAA80350.1| (U36451) N-(5'phosphoribosyl)anthranilate isomerase [Shuttle vector pBD-GAL4] >gi|1052967|gb|AAA80671.1| (U37457) N-(5'-phosphoribosyl)-anthranilate isomerase [Cloning vector YATAG200] >gi|1052971|gb|AAA80674.1| (U37458) N-(5'-phosphoribosyl)-anthranilate isomerase [Cloning vector YRTAG300] Length = 233 Score = 73.7 bits (178), Expect = 1e-12 Identities = 67/220 (30%), Positives = 101/220 (45%), Gaps = 28/220 (12%) Query: 3 VKVCGVKSLEELEI-VEKYADATGVVVNSKSKRNVPLDAAREIISSAKI-------PVFL 54 VKVCG++S E E ++ AD G++ KR + AR+I S K P +L Sbjct: 23 VKVCGLQSTEAAECALDSDADLLGIICVPNRKRTIDPVIARKISSLVKAYKNSSGTPKYL 82 Query: 55 VSTMKN--REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPE 112 V +N +ED + +Q+H D S Y ++ G+ ++K P Sbjct: 83 VGVFRNQPKEDVLALVNDYGIDIVQLHGD--ESWQEY-QEFLGLPVIKRLVFP------- 132 Query: 113 RDAQMLLKKI-RKYEADLILLDTGAGS-------GKMHDLRVTRIVAEEIPVVVAGGLKP 164 +D +LL +K + + L D+ AG + D + E + ++AGGL P Sbjct: 133 KDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSISDWVGRQESPESLHFMLAGGLTP 192 Query: 165 ENVEMVIKLVKPFGVDVSSGVERNGKKDEELVREFVRRAK 204 ENV ++L GVDVS GVE NG KD + FV+ AK Sbjct: 193 ENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANFVKNAK 232 >gb|AAA87582.1| (U46126) chloramphenicol resistance protein [synthetic construct] Length = 233 Score = 73.7 bits (178), Expect = 1e-12 Identities = 67/220 (30%), Positives = 101/220 (45%), Gaps = 28/220 (12%) Query: 3 VKVCGVKSLEELEI-VEKYADATGVVVNSKSKRNVPLDAAREIISSAKI-------PVFL 54 VKVCG++S E E ++ AD G++ KR + AR+I S K P +L Sbjct: 23 VKVCGLQSTEAAECALDSDADLLGIICVPNRKRTIDPVIARKISSLVKAYKNSSGTPKYL 82 Query: 55 VSTMKN--REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPE 112 V +N +ED + +Q+H D S Y ++ G+ ++K P Sbjct: 83 VGVFRNQPKEDVLALVNDYGIDIVQLHGD--ESWQEY-QEFLGLPVIKRLVFP------- 132 Query: 113 RDAQMLLKKI-RKYEADLILLDTGAGS-------GKMHDLRVTRIVAEEIPVVVAGGLKP 164 +D +LL +K + + L D+ AG + D + E + ++AGGL P Sbjct: 133 KDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSISDWVGRQESPESLHFMLAGGLTP 192 Query: 165 ENVEMVIKLVKPFGVDVSSGVERNGKKDEELVREFVRRAK 204 ENV ++L GVDVS GVE NG KD + FV+ AK Sbjct: 193 ENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANFVKNAK 232 >sp|P13997|TRPF_KLULA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|68277|pir||ISVKNL phosphoribosylanthranilate isomerase (EC 5.3.1.24) - yeast (Kluyveromyces marxianus var. lactis) >gi|2902|emb|CAA32445.1| (X14230) N-(5'-phosphoribosyl)anthranilate isomerase (AA 1-210) [Kluyveromyces lactis] Length = 210 Score = 73.4 bits (177), Expect = 2e-12 Identities = 67/221 (30%), Positives = 105/221 (47%), Gaps = 31/221 (14%) Query: 1 MFVKVCGVKSLEELEI-VEKYADATGVVVNSKSKRNVPLDAAREIISSAKIP-----VFL 54 M VKVCG++++E + V+ AD G++ KR + A+ I ++ L Sbjct: 1 MLVKVCGLQTVEAAKTAVDDGADYLGIICVPGRKRTIDSSVAKGISTAVHQQENVKGTKL 60 Query: 55 VSTMKNR--EDWEVAIERTEARYIQIHSDVE----PSLLPYLKDEYGVEIMKAFRVPQES 108 V +N+ +D IQ+H D + SL+P + I+K F+ PQ Sbjct: 61 VGVFRNQSVDDVLQLYHEYNLDVIQLHGDEDIKEYRSLIPS-----SIPIIKRFQFPQ-- 113 Query: 109 ENPERDAQMLLKKIRKYEADLILLDTGAGSGKMHDLRVTRIVA-----EEIPVVVAGGLK 163 D ++LL + L L D+G G G L + I + EI ++AGGL Sbjct: 114 -----DCELLLDLYEHVDNVLTLFDSGEG-GTGEKLNWSAISSWSASHPEIKFIIAGGLN 167 Query: 164 PENVEMVIKLV-KPFGVDVSSGVERNGKKDEELVREFVRRA 203 P+NV + I ++ GVDVS GVE +G KD E V+ F+++A Sbjct: 168 PDNVSVAINMLPNAIGVDVSGGVETDGIKDLEKVKLFIQQA 208 >sp|P00912|TRPF_YEAST N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|68276|pir||ISBYN phosphoribosylanthranilate isomerase (EC 5.3.1.24) - yeast (Saccharomyces cerevisiae) Length = 224 Score = 72.6 bits (175), Expect = 3e-12 Identities = 66/220 (30%), Positives = 101/220 (45%), Gaps = 28/220 (12%) Query: 3 VKVCGVKSLEELEI-VEKYADATGVVVNSKSKRNVPLDAAREIISSAKI-------PVFL 54 VKVCG++S E E ++ AD G++ KR + AR+I + K P +L Sbjct: 14 VKVCGLQSTEAAECALDSDADLLGIICVPNRKRTIDPVIARKISTLVKAYKNSSGTPKYL 73 Query: 55 VSTMKN--REDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPE 112 V +N +ED + +Q+H D S Y ++ G+ ++K P Sbjct: 74 VGVFRNQPKEDVLALVNDYGIDIVQLHGD--ESWQEY-QEFLGLPVIKRLVFP------- 123 Query: 113 RDAQMLLKKI-RKYEADLILLDTGAGS-------GKMHDLRVTRIVAEEIPVVVAGGLKP 164 +D +LL +K + + L D+ AG + D + E + ++AGGL P Sbjct: 124 KDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSISDWVGRQESPESLHFMLAGGLTP 183 Query: 165 ENVEMVIKLVKPFGVDVSSGVERNGKKDEELVREFVRRAK 204 ENV ++L GVDVS GVE NG KD + FV+ AK Sbjct: 184 ENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANFVKNAK 223 >sp|P24920|TRPC_PHYPR TRYPTOPHAN BIOSYNTHESIS PROTEIN TRP1 [INCLUDES: INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS); N-(5'-PHOSPHO-RIBOSYL)ANTHRANILATE ISOMERASE (PRAI)] >gi|169310|gb|AAA33751.1| (M64473) N-(5'-phosphoribosyl)anthranilate isomerase indole-3-glycerol-phosphate synthase [Phytophthora parasitica] Length = 531 Score = 70.6 bits (170), Expect = 1e-11 Identities = 66/248 (26%), Positives = 110/248 (43%), Gaps = 47/248 (18%) Query: 4 KVCGVKSLE-ELEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAK---------IPVF 53 KVCG+ ++E L + A+ G+++ S R V + A+ I + + + Sbjct: 270 KVCGITTVEYALAALRNGANMIGIIMAEHSPRYVEKEEAKAIAKAVREYGERTGPILSDI 329 Query: 54 LVSTMKNREDW-------------------EVAIERTEARYIQIHSDVEPSLLPYLKDEY 94 L S + ++ DW V + +T ++ L+ DE Sbjct: 330 LESHLDDKSDWFHRNVLALREACSRAPLVVGVFVNKTATEMNAAAEEIGLDLVQLHGDE- 388 Query: 95 GVEIMK--------AFRVPQESENPERDAQMLLKKIRKYEADLILLDTGA-----GSGKM 141 G EI K A +P ++ DA+ +L+++ + A+ ILLDT G+G Sbjct: 389 GFEICKDIKYPTIRALHLPDTAQCDGVDAEAVLQQVSEGLANYILLDTTVKGQQGGTGVA 448 Query: 142 HDLRVTRIVAE-EIPVVVAGGLKPENVEMVIKLVKPFGVDVSSGVERNGK---KDEELVR 197 D ++ I + +P ++AGGL PENV + + P GVDVSSGVE G KD + V Sbjct: 449 FDWKIAAIFTQARLPCLMAGGLTPENVVKALSVGHPVGVDVSSGVEVKGSPGVKDLDKVA 508 Query: 198 EFVRRAKN 205 F++ K+ Sbjct: 509 AFLKAVKD 516 >sp|Q59649|TRPF_PSEAE N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|11350623|pir||D83257 N-(5'phosphoribosyl)anthranilate (PRA) isomerase PA3113 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|1225911|dbj|BAA12028.1| (D83654) phosphoribosyl anthranilate isomerase [Pseudomonas aeruginosa] >gi|9949224|gb|AAG06501.1|AE004735_8 (AE004735) N-(5'phosphoribosyl)anthranilate (PRA) isomerase [Pseudomonas aeruginosa] Length = 211 Score = 69.5 bits (167), Expect = 3e-11 Identities = 66/206 (32%), Positives = 98/206 (47%), Gaps = 19/206 (9%) Query: 3 VKVCGVKSLEE-LEIVEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKNR 61 +K+CG+ +E+ L ADA G+V +KS R V + AREI+ + +P F+ S Sbjct: 6 IKICGITRVEDALAAAAAGADAIGLVFYAKSPRAVDIHRAREIVRA--LPPFVTSV---- 59 Query: 62 EDWEVAIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLLKK 121 + + + +I V LL + DE E + R P + ++ + Sbjct: 60 ---GLFVNASRCELGEILDAVPLDLLQFHGDERA-EDCEGHRRPYLKALRMKPGDDIVGR 115 Query: 122 IRKYE-ADLILLDT-----GAGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVK 175 Y A ILLDT G+G D + + P+V+AGGL P+NV ++ VK Sbjct: 116 AAAYPGAAGILLDTYVEGVPGGTGAAFDWSLVPTDLGK-PLVLAGGLTPDNVGRAVEQVK 174 Query: 176 PFGVDVSSGVERN-GKKDEELVREFV 200 P+ VDVS GVE + G KD VR FV Sbjct: 175 PYAVDVSGGVEASKGIKDAARVRAFV 200 >sp|P16923|TRPF_ACICA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|78096|pir||A34091 phosphoribosylanthranilate isomerase (EC 5.3.1.24) - Acinetobacter calcoaceticus >gi|141791|gb|AAA21897.1| (M34485) 5'-phosphoribosyl anthranilate isomerase [Acinetobacter calcoaceticus] >gi|141797|gb|AAA21901.1| (M58444) phosphoribosyl anthranilate isomerase [Acinetobacter calcoaceticus] Length = 213 Score = 69.1 bits (166), Expect = 4e-11 Identities = 56/205 (27%), Positives = 95/205 (46%), Gaps = 12/205 (5%) Query: 4 KVCGVKSLEELEI-VEKYADATGVVVNSKSKRNVPLDAAREIISSAKIPVFLVSTMKNRE 62 K+CG+ ++++ V ADA G+V S R+V + A+ ++ V +V N Sbjct: 6 KICGITRSQDVQAAVSAGADAIGLVFFPPSPRHVSIAQAQALLQHIPAYVQVVGLFVNAT 65 Query: 63 DWEV--AIERTEARYIQIHSDVEPSLLPYLKDEYGVEIMKAFRVPQESENPERDAQMLLK 120 ++ ++ +Q+H D P + + KA +V PE D ++ Sbjct: 66 ADQIKSVLDCVALDVLQLHGDETPEQCQEIALQCKRRWYKAIQV-----KPELDVVDEVQ 120 Query: 121 KIRKYEADLILLDTG---AGSGKMHDLRVTRIVAEEIPVVVAGGLKPENVEMVIKLVKPF 177 + + A +LLD G H ++ +IP+++AGGL PENV I+ F Sbjct: 121 RYQAAGASAVLLDAWHPELKGGTGHQFDWSKFPKLDIPLILAGGLTPENVVDAIQTTHAF 180 Query: 178 GVDVSSGVE-RNGKKDEELVREFVR 201 VDVS GVE G KD++L+ F++ Sbjct: 181 AVDVSGGVEAAKGIKDKQLIERFMQ 205 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.316 0.135 0.366 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 70842392 Number of Sequences: 2977 Number of extensions: 2809272 Number of successful extensions: 10485 Number of sequences better than 1.0e-10: 21 Number of HSP's better than 0.0 without gapping: 3 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 10459 Number of HSP's gapped (non-prelim): 21 length of query: 208 length of database: 189,106,746 effective HSP length: 59 effective length of query: 149 effective length of database: 153,796,013 effective search space: 22915605937 effective search space used: 22915605937 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 163 (67.9 bits)