BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2098 (cyaB-like2) DE:adenylyl cyclase related protein (183 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||B75152 adenylyl cyclase related protein PAB2098 - Pyrococcu... 370 e-102 pir||C71193 hypothetical protein PH1819 - Pyrococcus horikoshii ... 310 5e-84 sp|Q57692|Y240_METJA HYPOTHETICAL PROTEIN MJ0240 >gi|2128193|pir... 129 3e-29 gi|11499570 conserved hypothetical protein [Archaeoglobus fulgid... 125 3e-28 pir||F69084 conserved hypothetical protein MTH1629 - Methanobact... 118 3e-26 pir||G72559 hypothetical protein APE1761 - Aeropyrum pernix (str... 108 6e-23 gb|AAK40592.1| Adenylate cyclase, cyaB-type, putative (cyaB) [Su... 102 2e-21 gb|AAG19643.1| (AE005052) Vng1296c [Halobacterium sp. NRC-1] 85 6e-16 pir||G71093 hypothetical protein PH1012 - Pyrococcus horikoshii ... 75 7e-13 gb|AAC67074.1| (AE001172) conserved hypothetical protein [Borrel... 74 1e-12 pir||A75072 probable adenylyl cyclase, cyab-type PAB0653 - Pyroc... 74 1e-12 pir||B70190 conserved hypothetical protein BB0723 - Lyme disease... 72 4e-12 >pir||B75152 adenylyl cyclase related protein PAB2098 - Pyrococcus abyssi (strain Orsay) >gi|5457807|emb|CAB49297.1| (AJ248284) adenylyl cyclase related protein [Pyrococcus abyssi] Length = 183 Score = 370 bits (940), Expect = e-102 Identities = 183/183 (100%), Positives = 183/183 (100%) Query: 1 MYEVELKGYANEEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHH 60 MYEVELKGYANEEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHH Sbjct: 1 MYEVELKGYANEEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHH 60 Query: 61 EVFLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGIT 120 EVFLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGIT Sbjct: 61 EVFLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGIT 120 Query: 121 ITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVERFERKSYLELLLEASQKS 180 ITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVERFERKSYLELLLEASQKS Sbjct: 121 ITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVERFERKSYLELLLEASQKS 180 Query: 181 HHT 183 HHT Sbjct: 181 HHT 183 >pir||C71193 hypothetical protein PH1819 - Pyrococcus horikoshii >gi|3258255|dbj|BAA30938.1| (AP000007) 183aa long hypothetical protein [Pyrococcus horikoshii] Length = 183 Score = 310 bits (787), Expect = 5e-84 Identities = 150/176 (85%), Positives = 167/176 (94%), Gaps = 1/176 (0%) Query: 1 MYEVELKGYANEEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHH 60 MYEVELKGYAN+EIFEKVRET+ FMR+EIHEDIYYQHPCRDFSKTDEALRIRIKRFNGH+ Sbjct: 1 MYEVELKGYANDEIFEKVRETFEFMRKEIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHN 60 Query: 61 EVFLTYKGPKLDKRSKTRLEIEVEIQ-DTEKYFQLLQNLGFREVLRIVKTREKYYVDKGI 119 EVFLTYKGPK+D++SKTRLEIEVEIQ D +KYF+LL LGF+EVL++VKTREKYYV+KG+ Sbjct: 61 EVFLTYKGPKIDEKSKTRLEIEVEIQEDVDKYFELLDRLGFKEVLKVVKTREKYYVEKGV 120 Query: 120 TITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVERFERKSYLELLLE 175 TITLDEVEGLGKFIEIETLVKEK+EIP VEKLE ILR LGVE+FER+SYLELLLE Sbjct: 121 TITLDEVEGLGKFIEIETLVKEKDEIPEAVEKLEKILRELGVEKFERRSYLELLLE 176 >sp|Q57692|Y240_METJA HYPOTHETICAL PROTEIN MJ0240 >gi|2128193|pir||A64330 hypothetical protein MJ0240 - Methanococcus jannaschii >gi|1499018|gb|AAB98225.1| (U67479) conserved hypothetical protein [Methanococcus jannaschii] Length = 175 Score = 129 bits (320), Expect = 3e-29 Identities = 77/177 (43%), Positives = 117/177 (65%), Gaps = 10/177 (5%) Query: 1 MYEVELKGYANEE--IFEKVRET-YRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFN 57 M EVE+K +++ + E++++ ++F++++ EDIY+ RDF +TDEALRIR + N Sbjct: 1 MIEVEIKVKIDDKNKVVEQLKKLGFKFIKKKFQEDIYFNGIDRDFRETDEALRIRDEDGN 60 Query: 58 GHHEVFLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDK 117 F+TYKGPK+DK SKTR EIEV+I+D EK Q+ + LGF+EV I K RE Y + Sbjct: 61 ----FFVTYKGPKIDKISKTREEIEVKIEDKEKMRQIFKKLGFKEVPPIRKIRE-IYKKE 115 Query: 118 GITITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILR--NLGVERFERKSYLEL 172 I ++D+VEGLG F+E+E + + E + +E++ IL+ N+ + RKSYLEL Sbjct: 116 DIEASIDDVEGLGLFLELEKSISDINEKDKVLEEMMEILKALNISKDNIIRKSYLEL 172 >gi|11499570 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7447792|pir||C69498 conserved hypothetical protein AF1988 - Archaeoglobus fulgidus >gi|2648546|gb|AAB89262.1| (AE000965) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 175 Score = 125 bits (311), Expect = 3e-28 Identities = 77/179 (43%), Positives = 107/179 (59%), Gaps = 11/179 (6%) Query: 3 EVELKGYANEEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHHEV 62 EVE K E + EKV+E + + DIY+ HPCRDF+ +DEALRIR + Sbjct: 2 EVEAKFPYREGVEEKVKEIAELIIEKFEHDIYFSHPCRDFASSDEALRIR----QDVEGI 57 Query: 63 FLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGITIT 122 LTYKGPK+D +K+R E+++++++ E Q+L+ LGFR V + K R Y + + I I Sbjct: 58 TLTYKGPKVDVETKSREEVKLKVENFEAAKQILEKLGFRAVAEVKKLRRIYGLCEAI-IC 116 Query: 123 LDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVERFE--RKSYLELLLEASQK 179 LD+VEGLGKF+EIE E + I EK+ I LG R E R SYLEL+L+ + Sbjct: 117 LDDVEGLGKFVEIEV---EADNID-AKEKVFSIAEQLGYSRNESIRDSYLELILQKKSR 171 >pir||F69084 conserved hypothetical protein MTH1629 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622756|gb|AAB86102.1| (AE000922) conserved protein [Methanobacterium thermoautotrophicum] Length = 177 Score = 118 bits (294), Expect = 3e-26 Identities = 72/177 (40%), Positives = 109/177 (60%), Gaps = 9/177 (5%) Query: 1 MYEVELKG--YANEEIFEKVRETYRF-MRREIHEDIYYQHPCRDFSKTDEALRIRIKRFN 57 M EVE+K + +E+ +++ + E D+Y+ P RDF++TDEALRIR R Sbjct: 1 MIEVEVKAKIHDRDEMVDRILSVGGVHVSDEEQHDLYFNAPHRDFARTDEALRIR--RSG 58 Query: 58 GHHEVFLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDK 117 G F+TYKGPK+D+ SKTR E+E E+ D ++L++LGFR V +VK R Y V + Sbjct: 59 GR--TFITYKGPKIDEESKTRKELETEVADPGTAAEILESLGFRMVREVVKERRIYSVGE 116 Query: 118 GITITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVE-RFERKSYLELL 173 T+++D V GLG ++EIE + + + + ++ + R LG+E FER+SYLELL Sbjct: 117 -FTVSIDTVMGLGTYLEIERDLPDGSDYAGALREIFELYRKLGIEDGFERRSYLELL 172 >pir||G72559 hypothetical protein APE1761 - Aeropyrum pernix (strain K1) >gi|5105451|dbj|BAA80764.1| (AP000062) 169aa long hypothetical protein [Aeropyrum pernix] Length = 169 Score = 108 bits (266), Expect = 6e-23 Identities = 66/165 (40%), Positives = 95/165 (57%), Gaps = 13/165 (7%) Query: 12 EEIFEKVRETYRFMRRE-IHEDIYYQHPCRDFSKTDEALRIRIKRFNGHHEVFLTYKGPK 70 E I +R+ ++ E + DIYY+HPCRD DEALR+R+ NG LTYKGP+ Sbjct: 2 EYIEAALRDAGLYLEGERLEVDIYYRHPCRDMLSRDEALRLRVYEDNGGR---LTYKGPR 58 Query: 71 LDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGITITLDEVEGLG 130 + K R E+E+E+ E+ LL LGF E L +V+ R KYY +G+ +TLD VE LG Sbjct: 59 MGGGFKAREEVEIELTRVEEARLLLARLGFEETL-VVRKRRKYYRGEGVLVTLDNVESLG 117 Query: 131 KFIEIETLVKEKEEIPRTVEKLEGILRNLGVERFERKSYLELLLE 175 F+E+E E P +E LE +L+ +R ++Y E+ L+ Sbjct: 118 CFVEVEA------EDPGGIEMLESLLKL--EDRRVDETYAEMALK 154 >gb|AAK40592.1| Adenylate cyclase, cyaB-type, putative (cyaB) [Sulfolobus solfataricus] Length = 186 Score = 102 bits (253), Expect = 2e-21 Identities = 66/174 (37%), Positives = 99/174 (55%), Gaps = 11/174 (6%) Query: 12 EEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHHEVFLTYKGPKL 71 EE+ E + + + + E ED+Y+ + R+F TDEA+RIRI + + LTYKGPKL Sbjct: 16 EELRESLGKDMKLLDVEKQEDVYFNYVYRNFKITDEAVRIRIN----NKGIELTYKGPKL 71 Query: 72 DKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGITITLDEVEGLGK 131 K R EI + + D K +LL+ +GF V+ I KTR Y+DK ++LD V+ LG+ Sbjct: 72 HSSLKAREEISITVNDLNKTIELLRKIGFYPVITIKKTRIN-YLDKSFIVSLDLVKDLGQ 130 Query: 132 FIEIETLVKEKEEIPRTVEKLEGILRNLGVE-RFERKSYLELLL---EASQKSH 181 FIEIE + + ++ +R ++ + KSYLELL+ EAS KS+ Sbjct: 131 FIEIEAINEISDQ--EIQNYTSNFIRKYKIKGKLTTKSYLELLIDKYEASSKSN 182 >gb|AAG19643.1| (AE005052) Vng1296c [Halobacterium sp. NRC-1] Length = 203 Score = 84.7 bits (206), Expect = 6e-16 Identities = 65/204 (31%), Positives = 94/204 (45%), Gaps = 38/204 (18%) Query: 1 MYEVELKGYANEEIFEKVRETYRFMRREIHE-----DIYYQHPCRDFSKTDEALRIRI-- 53 MYEVE+K +E VR + H D YY P R F +TDEA R+R Sbjct: 1 MYEVEVKVPGE---YETVRAALADVDAAEHTTVAQADTYYDAPHRAFEQTDEAFRLRRVA 57 Query: 54 -----------------------KRFNGHHEVFLTYKGPKLDKRSKTRLEIEVEIQDTEK 90 R +G V TYKGP ++ SKTR E E + D + Sbjct: 58 TAARGFERGDDLTADIDAVLSGPARADGESRV--TYKGPLVEAESKTREEFETAVGDDAQ 115 Query: 91 YFQLLQNLGFREVLRIVKTREKYYVDKGITITLDEVEGLGKFIEIETLVKEKEEIPRTVE 150 +++ LGF + K R K++ + G T+ LD VE +G+++EIET V+ + + E Sbjct: 116 MAAIIEQLGFESAAVVRKLRTKHHFE-GFTVLLDAVEDVGEYVEIETTVEAEHAVSGARE 174 Query: 151 KLEGILRNLGVERFE--RKSYLEL 172 +LR LG++ + R SYL L Sbjct: 175 DAYAVLRRLGLDPTDQIRTSYLGL 198 >pir||G71093 hypothetical protein PH1012 - Pyrococcus horikoshii >gi|3257426|dbj|BAA30109.1| (AP000004) 165aa long hypothetical protein [Pyrococcus horikoshii] Length = 165 Score = 74.5 bits (180), Expect = 7e-13 Identities = 56/175 (32%), Positives = 90/175 (51%), Gaps = 17/175 (9%) Query: 3 EVELKGYAN-EEIFEKVRET-YRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHH 60 E+E+K N E+I K+ +F E ED+Y++ P +R+++ N Sbjct: 2 EIEVKFRVNFEDIKRKIEGLGAKFFGIEEQEDVYFELPSPKL--------LRVRKINNTG 53 Query: 61 EVFLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGIT 120 + ++TYK LDKR++ E+E E+QD E +L + LGF+ V +VK R Y +T Sbjct: 54 KSYITYK-EILDKRNEEFYELEFEVQDPEGAIELFKRLGFK-VQGVVKKRRWIYKLNNVT 111 Query: 121 ITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGV--ERFERKSYLELL 173 L+ VE G F++IE + EE + + + R LG+ E E K Y+EL+ Sbjct: 112 FELNRVEKAGDFLDIEVITSNPEEGKKII---WDVARRLGLKEEDVEPKLYIELI 163 >gb|AAC67074.1| (AE001172) conserved hypothetical protein [Borrelia burgdorferi] Length = 177 Score = 74.1 bits (179), Expect = 1e-12 Identities = 47/185 (25%), Positives = 97/185 (52%), Gaps = 18/185 (9%) Query: 1 MYEVELKGYAN----EEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRF 56 M+E+E K + + I + + ++F++ EI DIYY +++ IRI++ Sbjct: 1 MFEIESKAFIPTKELKRIIKLANKKFKFIKEEIKTDIYY---------SNQKKIIRIRKL 51 Query: 57 NGHHEVFLTYKGPKLDKRSKTRL--EIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYY 114 N ++ +T+K LD + + EIE +I + L++ L F+++ + +K + Y Sbjct: 52 NTLEKI-VTFKKKILDNNNTVEINKEIEFKIDSINNFLTLIKELKFKKLYKKIK-KSLIY 109 Query: 115 VDKGITITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGV-ERFERKSYLELL 173 + + ++E++ LG F+EIE ++ + +I ++++ I+ G+ E E + Y ELL Sbjct: 110 QTNNLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIDNIINQFGLKENIETRPYSELL 169 Query: 174 LEASQ 178 A+Q Sbjct: 170 SLANQ 174 >pir||A75072 probable adenylyl cyclase, cyab-type PAB0653 - Pyrococcus abyssi (strain Orsay) >gi|5458390|emb|CAB49878.1| (AJ248286) adenylyl cyclase, CyaB-type, putative [Pyrococcus abyssi] Length = 170 Score = 73.7 bits (178), Expect = 1e-12 Identities = 49/181 (27%), Positives = 95/181 (52%), Gaps = 16/181 (8%) Query: 3 EVELKGYANEEIFEKVRE-TYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRFNGHHE 61 E+E+K +E+I E++ +F+ E+ ED+Y+ P +R++R + + Sbjct: 2 EIEIKFRVSEDIKERLESLNAKFVGLEVQEDVYFDVPLPKL--------LRVRRISNLGK 53 Query: 62 VFLTYKGPKLDKRSKTRLEIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYYVDKGITI 121 ++TYK +D+ ++ E+E E+ D ++ + LGF +V +K Y +T Sbjct: 54 SYITYK-EIMDRNNEEFYEVEFEVSDFNLAIEVFKRLGF-DVKASIKKERLIYKLGDVTF 111 Query: 122 TLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVER--FERKSYLELLLEASQK 179 L+++ GLG F++IE + + EE R K+ + LG+++ E + Y+EL+ E S + Sbjct: 112 ELNKIPGLGNFLDIEVISDDPEEAKR---KIWEVAEKLGLKKKDVEPRLYIELVNELSSR 168 Query: 180 S 180 S Sbjct: 169 S 169 >pir||B70190 conserved hypothetical protein BB0723 - Lyme disease spirochete Length = 177 Score = 72.2 bits (174), Expect = 4e-12 Identities = 46/185 (24%), Positives = 96/185 (51%), Gaps = 18/185 (9%) Query: 1 MYEVELKGYAN----EEIFEKVRETYRFMRREIHEDIYYQHPCRDFSKTDEALRIRIKRF 56 M+E+E K + + I + + ++F++ EI D YY +++ IRI++ Sbjct: 1 MFEIESKAFIPTKELKRIIKLANKKFKFIKEEIKTDXYY---------SNQKKIIRIRKL 51 Query: 57 NGHHEVFLTYKGPKLDKRSKTRL--EIEVEIQDTEKYFQLLQNLGFREVLRIVKTREKYY 114 N ++ +T+K LD + + EIE +I + L++ L F+++ + +K + Y Sbjct: 52 NTLEKI-VTFKKKILDNNNTVEINKEIEFKIDSINNFLTLIKELKFKKLYKKIK-KSLIY 109 Query: 115 VDKGITITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGV-ERFERKSYLELL 173 + + ++E++ LG F+EIE ++ + +I ++++ I+ G+ E E + Y ELL Sbjct: 110 QTNNLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIDNIINQFGLKENIETRPYSELL 169 Query: 174 LEASQ 178 A+Q Sbjct: 170 SLANQ 174 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.319 0.140 0.387 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63111528 Number of Sequences: 2977 Number of extensions: 2558733 Number of successful extensions: 8437 Number of sequences better than 1.0e-10: 12 Number of HSP's better than 0.0 without gapping: 2 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 8418 Number of HSP's gapped (non-prelim): 13 length of query: 183 length of database: 189,106,746 effective HSP length: 56 effective length of query: 127 effective length of database: 155,591,474 effective search space: 19760117198 effective search space used: 19760117198 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 162 (67.5 bits)