BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2139 (secY) DE:protein translocase subunit (secY)
(468 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75145 protein translocase chain (secy) PAB2139 - Pyrococcu... 931 0.0
pir||E71184 probable preprotein translocase secY subunit - Pyroc... 887 0.0
pir||F69132 preprotein translocase SecY - Methanobacterium therm... 396 e-109
pir||F64359 preprotein translocase secY [similarity] - Methanoco... 393 e-108
sp|Q60175|SECY_METJA PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|282... 393 e-108
sp|P28541|SECY_METVA PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|991... 391 e-107
gi|11499486 protein translocase, subunit SEC61 alpha (secY) [Arc... 353 4e-96
emb|CAC12372.1| (AL445067) protein translocase SEC61 (secY), sub... 332 6e-90
pir||G72695 probable preprotein translocate secY subunit APE0983... 323 3e-87
gb|AAC38988.1| (AF006204) PfSec61 [Plasmodium falciparum] 321 8e-87
gb|AAG19959.1| (AE005077) protein translocase; SecY [Halobacteri... 307 2e-82
sp|P28542|SECY_HALMA PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|991... 295 6e-79
gb|AAF18411.1|AF190652_1 (AF190652) putative integral membrane p... 294 2e-78
gb|AAF80449.1|AF161718_1 (AF161718) Sec61p [Triticum aestivum] 288 8e-77
gb|AAC83037.1| (AC005679) Strong similarity to F13P17.9 gi|33373... 287 1e-76
gi|7019415 sec61 homolog [Homo sapiens] >gi|8394252|ref|NP_05860... 287 2e-76
sp|P38377|S61A_CANFA PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUN... 286 4e-76
pir||T02313 endoplasmic reticulum insertion protein F13P17.9 - A... 284 2e-75
pir||T27227 hypothetical protein Y57G11C.15 - Caenorhabditis ele... 282 8e-75
gi|10946604 Sec61 alpha isoform 2 [Mus musculus] >gi|7673003|gb|... 281 1e-74
gb|AAF88109.1|AC021043_2 (AC021043) Putative protein transport p... 281 1e-74
sp|P38379|S61A_PYRSA PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUN... 279 4e-74
gi|7705736 sec61 homolog [Homo sapiens] >gi|4689112|gb|AAD27765.... 279 7e-74
gb|AAK40996.1| Preprotein translocase secY subunit (secY) [Sulfo... 275 6e-73
sp|P49978|SECY_SULAC PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|212... 275 6e-73
sp|Q9UX84|SECY_SULSO PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|601... 275 6e-73
sp|P79088|S61A_SCHPO PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUN... 269 6e-71
sp|Q25147|S61A_HALRO PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUN... 267 2e-70
pir||T12065 endoplasmic reticulum insertion protein SEC61 - yeas... 264 2e-69
sp|P78979|S61A_YARLI PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT 264 2e-69
emb|CAB90210.1| (AJ238713) SEC61 protein [Candida albicans] 260 3e-68
gi|6323411 membrane component of ER protein translocation appara... 259 6e-68
gb|AAF52389.1| (AE003613) CG9539 gene product [Drosophila melano... 251 1e-65
dbj|BAB14148.1| (AK022640) unnamed protein product [Homo sapiens] 230 2e-59
gi|8922530 hypothetical protein FLJ10578 [Homo sapiens] >gi|7022... 151 2e-35
gi|6319760 Probable SEC61 protein homolog; Ssh1p [Saccharomyces ... 147 2e-34
gb|AAF34691.1|AF222906_1 (AF222906) Sec61p [Candida albicans] 141 1e-32
emb|CAB57249.1| (AJ270222) hypothetical protein [Entodinium caud... 116 7e-25
emb|CAC05722.1| (AL391743) protein transport protein sec61 alpha... 94 4e-18
sp|O66491|SECY_AQUAE PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|744... 81 3e-14
pir||T39848 protein transport protein sec61 alpha homolog [impor... 80 6e-14
sp|P16336|SECY_BACSU PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|762... 76 8e-13
dbj|BAA00495.1| (D00619) SecY [Bacillus subtilis] 76 8e-13
sp|P57571|SECY_BUCAI PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|100... 71 3e-11
>pir||A75145 protein translocase chain (secy) PAB2139 - Pyrococcus abyssi
(strain Orsay) >gi|5457750|emb|CAB49240.1| (AJ248284)
protein translocase subunit (secY) [Pyrococcus abyssi]
Length = 468
Score = 931 bits (2381), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQ 60
MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQ
Sbjct: 1 MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQ 60
Query: 61 FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVF 120
FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVF
Sbjct: 61 FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVF 120
Query: 121 MCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLF 180
MCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLF
Sbjct: 121 MCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLF 180
Query: 181 IAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPD 240
IAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPD
Sbjct: 181 IAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPD 240
Query: 241 MMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRYPIRFLYVSNIPIILTFALYANIQ 300
MMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRYPIRFLYVSNIPIILTFALYANIQ
Sbjct: 241 MMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRYPIRFLYVSNIPIILTFALYANIQ 300
Query: 301 LWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSL 360
LWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSL
Sbjct: 301 LWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSL 360
Query: 361 IFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALI 420
IFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALI
Sbjct: 361 IFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALI 420
Query: 421 AVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRRFFAT 468
AVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRRFFAT
Sbjct: 421 AVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRRFFAT 468
>pir||E71184 probable preprotein translocase secY subunit - Pyrococcus
horikoshii >gi|3258185|dbj|BAA30868.1| (AP000007) 468aa
long hypothetical preprotein translocase secY subunit
[Pyrococcus horikoshii]
Length = 468
Score = 887 bits (2266), Expect = 0.0
Identities = 435/466 (93%), Positives = 455/466 (97%)
Query: 1 MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQ 60
MGARD+IYA+EKWFPEVERPKKHVPLKEKF+WTGLAL+LYYVLAEIPVYGIP++IQDYFQ
Sbjct: 1 MGARDVIYAMEKWFPEVERPKKHVPLKEKFVWTGLALVLYYVLAEIPVYGIPKKIQDYFQ 60
Query: 61 FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVF 120
FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSE+I+LDLANPEDRRFYQALQRVFSVF
Sbjct: 61 FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSELIRLDLANPEDRRFYQALQRVFSVF 120
Query: 121 MCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLF 180
MCF EAAIWVLGGAFGRVGVDVTY IA LMI+QLA GGIILIVLDELVSKWGIGSGISLF
Sbjct: 121 MCFFEAAIWVLGGAFGRVGVDVTYTIATLMIIQLALGGIILIVLDELVSKWGIGSGISLF 180
Query: 181 IAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPD 240
IAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHIL GDLKGALYRGG+APD
Sbjct: 181 IAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILDGDLKGALYRGGSAPD 240
Query: 241 MMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRYPIRFLYVSNIPIILTFALYANIQ 300
M+AV ATIIVFLVVVYFESMRVEIPLGYRGVTIRGRYPI+FLYVSNIPIILTFALYANIQ
Sbjct: 241 MIAVTATIIVFLVVVYFESMRVEIPLGYRGVTIRGRYPIKFLYVSNIPIILTFALYANIQ 300
Query: 301 LWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSL 360
LWARVLDR GHPWLG FDP TGNP+GGFVLYVIPPR+IFTVIDNPVRA++YLILT+I SL
Sbjct: 301 LWARVLDRFGHPWLGRFDPVTGNPIGGFVLYVIPPRNIFTVIDNPVRAIIYLILTIIFSL 360
Query: 361 IFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALI 420
+FGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALI
Sbjct: 361 LFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALI 420
Query: 421 AVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRRFF 466
+VLADFLGALGTGTGILLTVGILYRFYEEIAREQI+EMFPALRR F
Sbjct: 421 SVLADFLGALGTGTGILLTVGILYRFYEEIAREQITEMFPALRRLF 466
>pir||F69132 preprotein translocase SecY - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621063|gb|AAB84535.1| (AE000796)
preprotein translocase SecY [Methanobacterium
thermoautotrophicum]
Length = 456
Score = 396 bits (1006), Expect = e-109
Identities = 216/456 (47%), Positives = 291/456 (63%), Gaps = 23/456 (5%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFLRVVLAGRNGSIL 74
P+V+ P VP +EK WTG+ L+LY+ LA+IP+YG+ D F R VLAG GSIL
Sbjct: 16 PQVKSPGYRVPFREKLKWTGIILVLYFFLAQIPLYGLSANAVDQFAQFRAVLAGNFGSIL 75
Query: 75 TLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGGA 134
TLGIGPIV+A IILQLLVG +I+KLDL+ ED+ F+Q LQ++ ++ F EA I+VL G+
Sbjct: 76 TLGIGPIVSASIILQLLVGGKILKLDLSRHEDKAFFQGLQKLLAIVFTFFEALIFVLTGS 135
Query: 135 FGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAAGVSQRILTRSL 194
+ ++ILQL GGI++I LDE+VSKWG GSG+ LFIAAGVSQ I+ +
Sbjct: 136 LAPSAPQFVW----VLILQLTIGGILIIFLDEVVSKWGFGSGVGLFIAAGVSQEIIVGAF 191
Query: 195 NPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMAVIATIIVFLVV 254
NPL+ P G PA G I F+ + G Y ++ V+A I VFLVV
Sbjct: 192 NPLSAPT----QPGVPA--GRITGFLYLLFTGQSPDFQYY------VLPVLALIAVFLVV 239
Query: 255 VYFESMRVEIPLGYRGVT-----IRGRYPIRFLYVSNIPIILTFALYANIQLWARVLDRL 309
VY ESMRVEIP+ G G+YP+RF+Y SN+P+ILT AL N+QL A V +L
Sbjct: 240 VYAESMRVEIPISMGGGKRLSRGAVGKYPLRFIYASNMPVILTSALLLNVQLLANVFQKL 299
Query: 310 GHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSLIFGFLWVEL 369
G+P LGT + G V G + PRSI +I +P R + Y ++ + ++F +LWVE+
Sbjct: 300 GYPILGTV--SNGQAVDGLAYLLTAPRSIDALILDPFRVVFYAVVFIGLCVLFAWLWVEI 357
Query: 370 TGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAVLADFLGA 429
+ + R +ARQL + G+QIPGFR E++L++YIP +T G V L+A +AD G+
Sbjct: 358 SNIGPRHVARQLYQMGMQIPGFRSSRGQFEKILKRYIPTITILGGAFVGLLAFVADLTGS 417
Query: 430 LGTGTGILLTVGILYRFYEEIAREQISEMFPALRRF 465
LG GTG+LLTVGI+YR YEEIA+EQ+ +M P LR F
Sbjct: 418 LGGGTGVLLTVGIVYRLYEEIAQEQLMDMHPILRSF 453
>pir||F64359 preprotein translocase secY [similarity] - Methanococcus jannaschii
Length = 440
Score = 393 bits (998), Expect = e-108
Identities = 212/462 (45%), Positives = 304/462 (64%), Gaps = 32/462 (6%)
Query: 4 RDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFLR 63
+ +I +EK PEVE P K + KEK WTG+ L+LY+++ I VY +I F+F +
Sbjct: 6 KKLIPILEK-IPEVELPVKEITFKEKLKWTGIVLVLYFIMGCIDVYTAGAQIPAIFEFWQ 64
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
+ A R G+++TLGIGPIVTAGII+QLLVGS II++DL+ PE+R +Q Q++ S+ MCF
Sbjct: 65 TITASRIGTLITLGIGPIVTAGIIMQLLVGSGIIQMDLSIPENRALFQGCQKLLSIIMCF 124
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAA 183
+EA ++V GAFG +T +A L+I+Q+AFG IILI LDE+VSK+GIGSGI LFIAA
Sbjct: 125 VEAVLFVGAGAFG----ILTPLLAFLVIIQIAFGSIILIYLDEIVSKYGIGSGIGLFIAA 180
Query: 184 GVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMA 243
GVSQ I +L P G + F+ +++G + Y +
Sbjct: 181 GVSQTIFVGALGP----------------EGYLWKFLNSLIQG-VPNIEY-------IAP 216
Query: 244 VIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLW 302
+I TIIVFL+VVY E MRVEIPL + + G+YPI+F+YVSNIP+IL AL+ANIQLW
Sbjct: 217 IIGTIIVFLMVVYAECMRVEIPLAHGRIKGAVGKYPIKFVYVSNIPVILAAALFANIQLW 276
Query: 303 ARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSLIF 362
L R+G P LG ++ G V G Y+ P + +VI +P+ A+VY+I +I+ ++F
Sbjct: 277 GLALYRMGIPILGHYE--GGRAVDGIAYYLSTPYGLSSVISDPIHAIVYMIAMIITCVMF 334
Query: 363 GFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAV 422
G WVE TGLD +++A+++ G+ I GFR+ + +E L++YIP +T S V +A
Sbjct: 335 GIFWVETTGLDPKSMAKRIGSLGMAIKGFRKSEKAIEHRLKRYIPPLTVMSSAFVGFLAT 394
Query: 423 LADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRR 464
+A+F+GALG GTG+LLTV I+YR YE++ RE++SE+ PA+ +
Sbjct: 395 IANFIGALGGGTGVLLTVSIVYRMYEQLLREKVSELHPAIAK 436
>sp|Q60175|SECY_METJA PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|2826286|gb|AAB98469.1|
(U67498) protein translocase, subunit SEC61 alpha (secY)
[Methanococcus jannaschii]
Length = 436
Score = 393 bits (998), Expect = e-108
Identities = 212/462 (45%), Positives = 304/462 (64%), Gaps = 32/462 (6%)
Query: 4 RDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFLR 63
+ +I +EK PEVE P K + KEK WTG+ L+LY+++ I VY +I F+F +
Sbjct: 2 KKLIPILEK-IPEVELPVKEITFKEKLKWTGIVLVLYFIMGCIDVYTAGAQIPAIFEFWQ 60
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
+ A R G+++TLGIGPIVTAGII+QLLVGS II++DL+ PE+R +Q Q++ S+ MCF
Sbjct: 61 TITASRIGTLITLGIGPIVTAGIIMQLLVGSGIIQMDLSIPENRALFQGCQKLLSIIMCF 120
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAA 183
+EA ++V GAFG +T +A L+I+Q+AFG IILI LDE+VSK+GIGSGI LFIAA
Sbjct: 121 VEAVLFVGAGAFG----ILTPLLAFLVIIQIAFGSIILIYLDEIVSKYGIGSGIGLFIAA 176
Query: 184 GVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMA 243
GVSQ I +L P G + F+ +++G + Y +
Sbjct: 177 GVSQTIFVGALGP----------------EGYLWKFLNSLIQG-VPNIEY-------IAP 212
Query: 244 VIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLW 302
+I TIIVFL+VVY E MRVEIPL + + G+YPI+F+YVSNIP+IL AL+ANIQLW
Sbjct: 213 IIGTIIVFLMVVYAECMRVEIPLAHGRIKGAVGKYPIKFVYVSNIPVILAAALFANIQLW 272
Query: 303 ARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSLIF 362
L R+G P LG ++ G V G Y+ P + +VI +P+ A+VY+I +I+ ++F
Sbjct: 273 GLALYRMGIPILGHYE--GGRAVDGIAYYLSTPYGLSSVISDPIHAIVYMIAMIITCVMF 330
Query: 363 GFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAV 422
G WVE TGLD +++A+++ G+ I GFR+ + +E L++YIP +T S V +A
Sbjct: 331 GIFWVETTGLDPKSMAKRIGSLGMAIKGFRKSEKAIEHRLKRYIPPLTVMSSAFVGFLAT 390
Query: 423 LADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRR 464
+A+F+GALG GTG+LLTV I+YR YE++ RE++SE+ PA+ +
Sbjct: 391 IANFIGALGGGTGVLLTVSIVYRMYEQLLREKVSELHPAIAK 432
>sp|P28541|SECY_METVA PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|99134|pir||S24065
preprotein translocase secY [validated] - Methanococcus
vannielii >gi|44772|emb|CAA43978.1| (X62045) SECY
[Methanococcus vannielii]
Length = 438
Score = 391 bits (993), Expect = e-107
Identities = 210/460 (45%), Positives = 295/460 (63%), Gaps = 29/460 (6%)
Query: 7 IYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFLRVVL 66
I I + PEV+RP K V KEK WTGL LILY++L I +Y + F F + V
Sbjct: 3 IKPILELIPEVKRPLKGVSFKEKIQWTGLVLILYFILGTIDIYMGGAEMPAMFAFWQTVT 62
Query: 67 AGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEA 126
A + G+++TLGIGPIVTAGII+QLLVGSE+I LDL+ P +R +Q LQ++F +F+CFLEA
Sbjct: 63 ASKMGTLITLGIGPIVTAGIIMQLLVGSELISLDLSKPMNRALFQGLQKLFGIFLCFLEA 122
Query: 127 AIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAAGVS 186
++V GAFG V +A +++LQLA G I++I LDE+VS++GIGSGI LFIAAGV+
Sbjct: 123 VMFVGAGAFG----VVNSTLALILVLQLALGAILVIYLDEIVSRYGIGSGIGLFIAAGVA 178
Query: 187 QRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMAVIA 246
Q I G G + F + G L G ++ +++
Sbjct: 179 QTI----------------FVGAFGAEGYLWKFFSAMSVGSL------GIAFEYILPILS 216
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARV 305
T+ VFLVVVY ES+RVEIPL + V G+YPI+F+YVSN+P+IL AL+ANIQLW
Sbjct: 217 TLFVFLVVVYVESIRVEIPLAHGRVKGAVGKYPIKFIYVSNLPVILAAALFANIQLWGMF 276
Query: 306 LDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSLIFGFL 365
LDR+G+P LG + + G V G Y P I +I +P+ A+ Y ++ VI ++FG
Sbjct: 277 LDRMGYPILGQY--SNGTAVSGIAYYFSTPYGISNIISDPLHAIFYTLMMVIFCILFGLF 334
Query: 366 WVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAVLAD 425
WVE +GLDA+++A++L + I GFR+ +++E+ L++YI +T GS V +A AD
Sbjct: 335 WVETSGLDAKSMAKKLGNLDMAIKGFRKSQKSIEQRLKRYIKPITVMGSAFVGFLAAAAD 394
Query: 426 FLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRRF 465
F GALG GTG+LLTV I+YR YE++ +EQ+SE+ PA+ +F
Sbjct: 395 FTGALGGGTGVLLTVSIVYRLYEQLVQEQLSELHPAVAKF 434
>gi|11499486 protein translocase, subunit SEC61 alpha (secY) [Archaeoglobus
fulgidus] >gi|7446502|pir||E69487 protein translocase,
subunit SEC61 alpha (secY) homolog - Archaeoglobus
fulgidus >gi|2648637|gb|AAB89347.1| (AE000971) protein
translocase, subunit SEC61 alpha (secY) [Archaeoglobus
fulgidus]
Length = 493
Score = 353 bits (895), Expect = 4e-96
Identities = 205/493 (41%), Positives = 296/493 (59%), Gaps = 43/493 (8%)
Query: 6 IIYAIEKWF---PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFL 62
+I A++ +F P VERPK HV +EKF WT L+LY++L+ +PV+G+ D F
Sbjct: 4 VIRALQPYFERIPSVERPKGHVHFREKFGWTAAILLLYFILSNVPVFGLSPESIDIFAAY 63
Query: 63 RVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMC 122
R + AG GSI+ LGIGPIVTA IILQLLVG+ IIKLDL NPEDR YQ QR M
Sbjct: 64 RALFAGSTGSIIALGIGPIVTASIILQLLVGAGIIKLDLTNPEDRAAYQDFQRFLVFVMI 123
Query: 123 FLEAAIWVLGGAF-------GRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGS 175
+EA + GG ++GV I+ L+ +QL GG++++ +DE+VSKWGIGS
Sbjct: 124 AVEAIPQIAGGLLKPDLNLAAQLGVS-PGIISFLIFIQLFIGGVLIVYMDEVVSKWGIGS 182
Query: 176 GISLFIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVG-AIPYFIQHILKGD-LKGALY 233
G+SLFI AG++Q I+ N + PN P P + A Y + + G L L
Sbjct: 183 GVSLFILAGIAQSIVVGLFNWVIPPNSAMPAGIIPRWIWIAQNYPLDQLFTGSGLAFLLI 242
Query: 234 RGGTAPDMMAVIATIIVFLVVVYFESMRVEIPLGY---RGVTIRGRYPIRFLYVSNIPII 290
+GG ++A+I T + L+VV+FE RVEIPL + RG RGR+PI+ +Y S +P+I
Sbjct: 243 QGG----ILALITTAAIILLVVFFEGTRVEIPLAHAVARGA--RGRFPIKLIYASVLPMI 296
Query: 291 LTFALYANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRA-- 348
AL AN+ +VL G G F G V G + ++ P S + I + V++
Sbjct: 297 FVRALQANVVALGQVLHARGVTIFGEF--VNGKAVSGLMFFLQPVSSPYDWIPSLVKSQG 354
Query: 349 ---------LVYL------ILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRR 393
++YL ++ V+ +IF + WVE +G+DART+A Q+ ++G+Q+PGFR+
Sbjct: 355 AAFAAIPDWMIYLHLLIDALILVVGGIIFAWFWVETSGMDARTVASQIAKSGMQVPGFRK 414
Query: 394 DPRTLERVLQKYIPYVTFWGSLTVALIAVLADFLGALG--TGTGILLTVGILYRFYEEIA 451
P+ LERVL +YIP VT G + ++ ++A+ LG +G +GTG+LL V I YRFYE++A
Sbjct: 415 SPQVLERVLSRYIPKVTILGGAIIGILTLVANMLGTIGNVSGTGLLLAVSIAYRFYEDLA 474
Query: 452 REQISEMFPALRR 464
+EQ++EM P +RR
Sbjct: 475 KEQLTEMHPLIRR 487
>emb|CAC12372.1| (AL445067) protein translocase SEC61 (secY), subunit alpha related
protein [Thermoplasma acidophilum]
Length = 535
Score = 332 bits (842), Expect = 6e-90
Identities = 199/516 (38%), Positives = 294/516 (56%), Gaps = 71/516 (13%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGI-PERIQDYFQFLRVVLAGRNGSI 73
P V++ K H+ K K MWT L ++LY+ L+ I +YG+ + D F R + AG +GS+
Sbjct: 24 PAVKKAKGHIEFKYKMMWTALIVVLYFALSNIYIYGLNTAQTIDVFASFREIFAGASGSL 83
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGIGPIVTA I++QL VG++I LDL N ED+ YQ +Q++ + M F+EA +
Sbjct: 84 MDLGIGPIVTASIVMQLFVGAKIFNLDLQNAEDKAIYQGVQKLLVIIMIFVEA----IPQ 139
Query: 134 AFGRVGVDVT--------------YAIAALMILQLAFGGIILIVLDELVSKWGIGSGISL 179
AFG + D + ++ILQL FG ++ ++DE+VSK+GIGSGISL
Sbjct: 140 AFGYLVPDTKVVNSINAVFPGYGEFLAQTIIILQLFFGSYLVFLMDEVVSKYGIGSGISL 199
Query: 180 FIAAGVSQRILTRSLNPLTDPNIID-PLTGKPAIVGAIP---YFIQHILKGDL--KGALY 233
FIAA VS+++ + N N + LT PA GA P Y I H L G +
Sbjct: 200 FIAADVSEQLFIGAFNWQALNNALTYSLTNPPA--GAFPKMFYIIMHSSSSYLLTNGVVQ 257
Query: 234 RGGTAPD-MMAVIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIIL 291
+ P+ M+AV+ T+++F +V YF+S ++E+P+ + V RGRYP++ LY SNIP+IL
Sbjct: 258 ILFSPPNPMIAVLGTLLIFFLVAYFQSSKIELPISHERVRGARGRYPLQLLYASNIPVIL 317
Query: 292 TFALYANIQLW------ARVLDR---LGH-PWLGTFDPTTGN----------PVGGFVLY 331
AL AN+ +W + VL + LGH P LG++ PTT P GG Y
Sbjct: 318 ATALLANVSMWTLLFWSSPVLSKVPILGHNPLLGSY-PTTAQATALNISATTPTGGLAYY 376
Query: 332 VIPPRSI-------------------FTVIDNPVRALVYLILTVISSLIFGFLWVELTGL 372
+ P + T + + +V+ V S++F W+E T +
Sbjct: 377 LFSPNGLSDWLFPILQPSGYQNILLGHTPLQEAIHIIVFTAFMVGFSVLFAIFWIETTNM 436
Query: 373 DARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAVLADFLGALG- 431
A +A+Q+Q +G+QIPGFRRDPR +ERVL+KYIP +T + V L+A A+ +G +G
Sbjct: 437 GASAVAKQIQASGMQIPGFRRDPRVMERVLKKYIPAITIFSGAVVGLLAAGANLIGTVGD 496
Query: 432 -TGTGILLTVGILYRFYEEIAREQISEMFPALRRFF 466
+GTG+LL VGI+ +FYE + REQ+ EM P +R+FF
Sbjct: 497 TSGTGLLLAVGIIIQFYEAMGREQLMEMHPVIRQFF 532
>pir||G72695 probable preprotein translocate secY subunit APE0983 - Aeropyrum
pernix (strain K1) >gi|5104652|dbj|BAA79967.1|
(AP000060) 494aa long hypothetical preprotein
translocate secY subunit [Aeropyrum pernix]
Length = 494
Score = 323 bits (819), Expect = 3e-87
Identities = 187/470 (39%), Positives = 282/470 (59%), Gaps = 26/470 (5%)
Query: 1 MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIP-ERIQDYF 59
+G D++ A+ + FP V +P++ L + WTG+ L+LY++++ IP+YGIP + I
Sbjct: 38 LGVIDVLAAVGERFPAVRKPERKPTLYRRLAWTGVILVLYFIMSNIPLYGIPPQNIGGQV 97
Query: 60 QFLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSV 119
R++ A G+++ LGIGPIVTA +I+Q+LVG++IIKLDLA+PE RR + + Q+V ++
Sbjct: 98 DLQRIIFASSAGTLMELGIGPIVTASLIIQVLVGAKIIKLDLADPEGRRKFTSAQKVLAL 157
Query: 120 FMCFLEAAIWVLGGAFGRVGVDVTYAIA--ALMILQLAFGGIILIVLDELVSK-WGIGSG 176
LEA + +GG + VG + AL+ LQL G +++I DE++ K WGIGS
Sbjct: 158 AFAALEAVAFTVGGRYW-VGTAIEPGPLDYALVSLQLFLGALLVIYFDEVMQKGWGIGSA 216
Query: 177 ISLFIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGG 236
ISLFI AGV+Q ++ +I + G G +P I + DL L R
Sbjct: 217 ISLFILAGVAQGVVW---------SIFGTIPGVAQDYGLVPAIISN---PDLT-LLARPN 263
Query: 237 TAPDMMAVIATIIVFLVVVYFESMRVEIPL-GYRGVTIRGRYPIRFLYVSNIPIILTFAL 295
PD+ T+ +++VY ++MRVEIP+ R IR R P++F+YV+NIPI+L L
Sbjct: 264 GFPDLTGFFTTLAAIILLVYLQAMRVEIPITSERFKGIRSRVPLQFIYVTNIPILLVGIL 323
Query: 296 YANIQLWARVL-DRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLIL 354
+++ L R+L D LG + V Y+ PPR + I +PV+ V++
Sbjct: 324 VSDLLLVQRLLADYLG------VESRAYQIYSSIVYYLSPPRGVVQSIADPVKTAVFIAS 377
Query: 355 TVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGS 414
+ S++FG++WVE+ GL+ R A +L + GL IPG R DPR LERVL++YI +TF S
Sbjct: 378 WTVLSIVFGYMWVEIAGLNPREQAERLIKGGLAIPGMRSDPRVLERVLRRYIYPLTFLSS 437
Query: 415 LTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRR 464
L VA + ++AD GA GTGTG+LL VGI+ ++Y I RE+ E +P LRR
Sbjct: 438 LIVAALVIVADIFGAYGTGTGLLLAVGIINQYYAMITRERALETYPLLRR 487
>gb|AAC38988.1| (AF006204) PfSec61 [Plasmodium falciparum]
Length = 472
Score = 321 bits (815), Expect = 8e-87
Identities = 173/453 (38%), Positives = 276/453 (60%), Gaps = 16/453 (3%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGI-PERIQDYFQFLRVVLAGRNGSI 73
PEV+ P + +P KEK +WT ++L ++ + +IP+YGI + D F ++RV+LA G++
Sbjct: 16 PEVQSPDRRLPFKEKLLWTAVSLFVFLICCQIPLYGIVTSKSSDPFYWMRVILASNRGTL 75
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+++QLL GS+II +D + EDR +Q Q++ + + EA +V+ G
Sbjct: 76 MELGISPIVTSGMVMQLLAGSKIIDVDQSLKEDRTLFQGAQKLLGLLITLGEAIAYVISG 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G + ++ A ++ILQL F G+++I+LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 IYGNIS-EIGTGHAIIIILQLFFAGVVVILLDELLQKGYGLGSGISLFIATNICETIMWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILK-GDLKGALYRGGTAPDMMAVIATIIVF 251
S +P T N + + AI+ I K LK A YR AP++ ++ATI+VF
Sbjct: 195 SFSPTTI-NTDKGIEFEGAIISLIYCLFTESNKISALKKAFYRTH-APNVTNLLATILVF 252
Query: 252 LVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARVLDR-- 308
L+V+Y + RV++ + Y+ V +G YPI+ Y SNIPIIL AL +N+ ++++L +
Sbjct: 253 LIVIYLQGFRVDLSVKYQSVRGQQGTYPIKLFYTSNIPIILQHALVSNLYFFSQILYKRF 312
Query: 309 -------LGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSLI 361
L W + T P+GG Y+ PP S + ++P LVY+ +++
Sbjct: 313 KNSILVNLIGQWQRSESSGTSIPIGGLAYYISPPNSFADITNDPFHTLVYISFVLVACAF 372
Query: 362 FGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIA 421
F W+E++G A+ +A+QL+ + + GFR P +L RV +YIP +G + +
Sbjct: 373 FSKTWIEVSGSSAKDVAKQLRDQQIGMRGFRDTPTSLTRVFNRYIPTAAAFGGCAIGALT 432
Query: 422 VLADFLGALGTGTGILLTVGILYRFYEEIAREQ 454
VLADFLGALG+GTGILL V I+Y+FYE + +EQ
Sbjct: 433 VLADFLGALGSGTGILLAVTIIYQFYEMLVKEQ 465
>gb|AAG19959.1| (AE005077) protein translocase; SecY [Halobacterium sp. NRC-1]
Length = 491
Score = 307 bits (778), Expect = 2e-82
Identities = 184/502 (36%), Positives = 274/502 (53%), Gaps = 51/502 (10%)
Query: 1 MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQ 60
MG ++ + P VERP+ HVP + K WTG L+LY+ L +P++GI D+F
Sbjct: 1 MGWKEAAAPVLTRMPAVERPEGHVPFRRKMYWTGGVLVLYFFLTNVPLWGIQTAGNDFFG 60
Query: 61 FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLAN-PEDRRFYQALQRVFSV 119
R +LAG G++L LGIGPIVTA I+LQLL G+ ++ LD N P D+ YQ LQ+
Sbjct: 61 QFRSLLAGGQGTVLQLGIGPIVTASIVLQLLGGANLLGLDTDNDPRDQAIYQGLQKFLVG 120
Query: 120 FMCFLEAAIWVLGGAFGRVGVDV-------TYAIAALMILQLAFGGIILIVLDELVSKWG 172
M L A V G F + + + + L+ Q+A GGI+L+ +DE++SKWG
Sbjct: 121 VMVVLTGAPMVFLGNFLQPSQQLAQSMPGGAFGVEVLIFAQIAAGGILLLFMDEVISKWG 180
Query: 173 IGSGISLFIAAGVSQRIL-----------TRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQ 221
+GSGI LFI AGVSQ ++ ++ L P I+ ++ P ++
Sbjct: 181 VGSGIGLFIVAGVSQSLVGGLVFWEGGVGSQGLLPTWFDIIVGNVSNMPPLLSG------ 234
Query: 222 HILKGDLKGALYRGGTAPDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIR 280
++ L + G ++ ++ T+ +++VVVY ES+RVEIPL + V RGR+P++
Sbjct: 235 ----SGIEFLLMQAG----ILGLLTTLFIYVVVVYAESVRVEIPLSHARVKGARGRFPVK 286
Query: 281 FLYVSNIPIILTFALYANIQLWARVLDRL---GHPWLGTFDPTTGNPVGGFVLYVIP--- 334
+Y S +P+IL AL ANIQ ++L+ WLG + G GG Y+ P
Sbjct: 287 LIYASVLPMILVRALQANIQFLGQILNSTLASMPTWLGVYG-GNGQVTGGLFYYLAPIYS 345
Query: 335 PRSIFTVIDNP--------VRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGL 386
P + +R + L +I IF WVE + ARQ+Q +G+
Sbjct: 346 PNAWMWWTSGATAARWQVLIRIAIDLSFMIIGGAIFAIFWVETADMGPDATARQIQNSGM 405
Query: 387 QIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAVLADFLGALG--TGTGILLTVGILY 444
QIPGFR++ +E+V+++YIP VT G V L+AV+A+ LG +G +GTG+LLT+ I Y
Sbjct: 406 QIPGFRKNQGVIEKVMERYIPQVTVIGGALVGLLAVMANMLGTIGNVSGTGLLLTISITY 465
Query: 445 RFYEEIAREQISEMFPALRRFF 466
+ YEEIA EQ+ EM P +R F
Sbjct: 466 KLYEEIAEEQMMEMHPMMREMF 487
>sp|P28542|SECY_HALMA PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|99182|pir||S22350 secY
protein - Haloarcula marismortui
>gi|43609|emb|CAA44838.1| (X63127) HmasecY [Haloarcula
marismortui]
Length = 487
Score = 295 bits (748), Expect = 6e-79
Identities = 184/488 (37%), Positives = 276/488 (55%), Gaps = 52/488 (10%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIP-ERIQDYFQFLRVVLAGRNGSI 73
P V+RP+ HVP K K WTG L+LY+ L + ++G+ + Q F +LA GSI
Sbjct: 15 PAVQRPEGHVPFKRKLTWTGGVLLLYFFLTNVKLFGLDIDASQQVFGRFSSILASGQGSI 74
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLAN-PEDRRFYQALQRVFSVFMCFLEAAIWVLG 132
+ LGIGPIVTA I+LQLL G++++ L+ + P D+ YQ LQ++ + M L V
Sbjct: 75 MQLGIGPIVTASIVLQLLGGADLLGLNTQDDPRDQILYQGLQKLLVLVMICLTGLPMVFA 134
Query: 133 GAFGRVGVDV-------TYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAAGV 185
G F V T + L+ Q+ GG++++ +DE++SKWG+GSGI LFI AGV
Sbjct: 135 GGFLPADTAVANSLGIGTAGVQWLIFAQMFVGGVLILFMDEVISKWGVGSGIGLFIVAGV 194
Query: 186 SQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQH------ILKGD-LKGALYRGGTA 238
+QR++ LT P L I+ FI +L D L+ L +G
Sbjct: 195 TQRLVG---GLLTAPF----LGNSEGIIYTWYLFITGERGTGPVLAADGLQTVLLQG--- 244
Query: 239 PDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYA 297
+++ + T+++F VVVY ES+RVEIPL V RGR+P++ +Y S +P+IL AL A
Sbjct: 245 -ELLGLFTTVLIFAVVVYAESVRVEIPLSNARVKGARGRFPVKLIYASVLPMILVRALQA 303
Query: 298 NIQLWARVLD-RLGH--PWLGTFDPTTGNPVGGFVLYVIPPRS--------------IFT 340
NIQ R+L+ +LG +LGT+ G P GG ++ P +S ++
Sbjct: 304 NIQFLGRILNAQLGSMPAFLGTY--ANGQPTGGLFYFLAPIQSRGDWMWWLEGTAQPVWQ 361
Query: 341 VIDNPVRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLER 400
++ R + L + ++ +F WVE T + A+Q+ +G+QIPGFR++ +E+
Sbjct: 362 IL---TRVGIDLFVMLVGGAVFAVFWVETTDMGPEATAKQIHNSGMQIPGFRQNVGVIEK 418
Query: 401 VLQKYIPYVTFWGSLTVALIAVLADFLGALG--TGTGILLTVGILYRFYEEIAREQISEM 458
VL++YIP VT G V L+AV+A+ LG +G +GTG+LLTV I Y+ YEEIA EQ+ EM
Sbjct: 419 VLERYIPQVTVIGGALVGLLAVMANMLGTIGGVSGTGLLLTVSITYKLYEEIAEEQLMEM 478
Query: 459 FPALRRFF 466
P +R+ F
Sbjct: 479 HPMMRQMF 486
>gb|AAF18411.1|AF190652_1 (AF190652) putative integral membrane protein [Phaseolus vulgaris]
Length = 476
Score = 294 bits (744), Expect = 2e-78
Identities = 168/463 (36%), Positives = 271/463 (58%), Gaps = 25/463 (5%)
Query: 13 WFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERI-QDYFQFLRVVLAGRNG 71
+ PEV+ + VP +EK ++T ++L ++ V +++P+YGI D F ++RV+LA G
Sbjct: 17 FLPEVQTADRKVPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFYWMRVILASNRG 76
Query: 72 SILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVL 131
+++ LGI PIVT+G+++QLL GS+II++D EDR Q++ + + EA +VL
Sbjct: 77 TVMELGITPIVTSGLVMQLLAGSKIIEVDNNVREDRALLNGAQKLLGILIAIGEAVAYVL 136
Query: 132 GGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRIL 190
G +G VG + A L+ILQL F GII+I LDEL+ K +G+GSGISLFIA + + I+
Sbjct: 137 SGMYGSVG-QLGVGNAILIILQLCFAGIIVICLDELLQKGYGLGSGISLFIATNICENII 195
Query: 191 TRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIA 246
++ +P T I+ G I F I + D L+ A YR P++ ++A
Sbjct: 196 WKAFSPTT----INSGRGAEFEGAVIALFHLLITRSDKVRALREAFYR-QNLPNVTNLLA 250
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARV 305
T+++FL+V+YF+ RV +P+ + +G YPI+ Y SN+PIIL AL +N+ +++
Sbjct: 251 TVLIFLIVIYFQGFRVVLPVRSKNARGQQGSYPIKLFYTSNMPIILQSALVSNLYFISQL 310
Query: 306 L----------DRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILT 355
L D LG + PVGG Y+ P S+ + NP AL YL+
Sbjct: 311 LHRKYSGNFFVDLLGKWKESEYGGGQSAPVGGIAYYITAPSSLADMAANPFHALFYLVFM 370
Query: 356 VISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSL 415
+ + +F W+E++G A+ +A+QL+ + +PG R L++ L +YIP +G +
Sbjct: 371 LSACALFSKTWIEVSGSSAKDVAKQLKEQQMVMPGHRES--NLQKELNRYIPTAAAFGGI 428
Query: 416 TVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEM 458
+ + VLADF+GA+G+GTGILL V I+Y+++E +E+ SE+
Sbjct: 429 CIGALTVLADFMGAIGSGTGILLAVTIIYQYFETFEKERASEL 471
>gb|AAF80449.1|AF161718_1 (AF161718) Sec61p [Triticum aestivum]
Length = 475
Score = 288 bits (730), Expect = 8e-77
Identities = 167/462 (36%), Positives = 271/462 (58%), Gaps = 24/462 (5%)
Query: 13 WFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERI-QDYFQFLRVVLAGRNG 71
+ PEV+ + +P +EK ++T ++L ++ V +++P+YGI D F ++RV+LA G
Sbjct: 17 FLPEVQSADRKIPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFYWMRVILASNRG 76
Query: 72 SILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVL 131
+++ LGI PIVT+G+++QLLVGS+II++D + EDR Q++ + + EA +VL
Sbjct: 77 TVMELGITPIVTSGMVMQLLVGSKIIEVDNSVREDRALLNGAQKLLGILIAIGEAVAYVL 136
Query: 132 GGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRIL 190
G +G V + A L+ILQL F GII+I LDEL+ K +G+GSGISLFIA + + I+
Sbjct: 137 SGMYGSVS-QLGTGNAILIILQLFFAGIIVICLDELLQKGYGLGSGISLFIATNICENII 195
Query: 191 TRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIA 246
++ +P T I+ G I F I + D L+ A YR P++ ++A
Sbjct: 196 WKAFSPTT----INSGRGAEFEGAVIALFHLLITRSDKVRALREAFYR-QNLPNVTNLLA 250
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARV 305
T++VFL+V+YF+ RV +P+ + +G YPI+ Y SN+PIIL AL N+ +++
Sbjct: 251 TVLVFLIVIYFQGFRVVLPVRSKNARGQQGSYPIKLFYTSNMPIILHSALITNLYFISQL 310
Query: 306 LDR---------LGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTV 356
L R L W + PVGG YV P S+ ++ NP AL Y++ +
Sbjct: 311 LYRKYSGNFLVNLLGIWKESEYSGHSIPVGGLAYYVTAPSSMADILANPFHALFYVVFML 370
Query: 357 ISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLT 416
+ +F W+E++G A+ +A+QL+ + +PG R L++ L KYIP +G +
Sbjct: 371 SACALFSKTWIEVSGSSAKDVAKQLKEQQMVMPGHRES--NLQKELNKYIPTAAAFGGVC 428
Query: 417 VALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEM 458
+ + VLADF+GA+G+GTGILL I+Y+++E +E+ +E+
Sbjct: 429 IGALTVLADFMGAIGSGTGILLADSIIYQYFETFEKERATEL 470
>gb|AAC83037.1| (AC005679) Strong similarity to F13P17.9 gi|3337356 transport
protein SEC61 alpha subunit homolog from Arabidopsis
thaliana BAC gb|AC004481
Length = 475
Score = 287 bits (728), Expect = 1e-76
Identities = 167/462 (36%), Positives = 276/462 (59%), Gaps = 24/462 (5%)
Query: 13 WFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERI-QDYFQFLRVVLAGRNG 71
+ PEV+ P++ +P +EK ++T ++L ++ V +++P+YGI D F ++RV+LA G
Sbjct: 17 FLPEVQSPERKIPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFYWMRVILASSRG 76
Query: 72 SILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVL 131
+++ LGI PIVT+G+++QLL GS+II++D EDR Q++ + + +A +VL
Sbjct: 77 TVMELGITPIVTSGMVMQLLAGSKIIEIDNNVREDRALLNGAQKLLGILIAVGQAVAYVL 136
Query: 132 GGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRIL 190
G +G VG ++ A L+I+QL F II++ LDEL+ K +G+GSGISLFIA + + I+
Sbjct: 137 SGMYGSVG-ELGVGNAILIIVQLCFAAIIVLCLDELLQKGYGLGSGISLFIATNICESII 195
Query: 191 TRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIA 246
++ +P T I+ G I F I + D L+ A +R P++ + A
Sbjct: 196 WKAFSPTT----INSGRGAQFEGAVIALFHLLITRTDKVRALREAFFR-QNLPNVTNLHA 250
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARV 305
T+++FL+V+YF+ RV +P+ + RG YPI+ Y SN+PIIL AL +NI +++
Sbjct: 251 TVLIFLIVIYFQGFRVVLPVRSKNARGQRGSYPIKLFYTSNMPIILQSALVSNIYFISQI 310
Query: 306 LDR-LGHPWL----GTFDPTTGN----PVGGFVLYVIPPRSIFTVIDNPVRALVYLILTV 356
L R G +L GT+ + + PVGG Y+ P S+ + +P AL YL+ +
Sbjct: 311 LYRKFGGNFLVNLIGTWKESEYSGQSIPVGGIAYYITAPSSLAEMATHPFHALFYLVFML 370
Query: 357 ISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLT 416
+ +F W+E++G A+ +ARQL+ + +PG R L++ L +YIP +G L
Sbjct: 371 AACALFSKTWIEVSGSSAKDVARQLREQQMVMPGHR--DSNLQKELNRYIPTAAAFGGLC 428
Query: 417 VALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEM 458
+ + VLAD +GA+G+GTGILL V I+Y+++E +E+ SE+
Sbjct: 429 IGALTVLADLMGAIGSGTGILLAVTIIYQYFETFEKEKASEL 470
>gi|7019415 sec61 homolog [Homo sapiens] >gi|8394252|ref|NP_058602.1| Sec61
alpha subunit homolog; transport protein sec61 alpha
subunit; Sec61 alpha subunit homolog (S. cerevisiae)
[Mus musculus] >gi|11450230|ref|XP_003286.1| sec61
homolog [Homo sapiens] >gi|585959|sp|P38378|S61A_RAT
PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT
>gi|206886|gb|AAA42125.1| (M96630) homologue to sec61
[Rattus rattus] >gi|5106795|gb|AAD39847.1| (AF084458)
sec61 homolog [Homo sapiens] >gi|6012186|dbj|BAA85159.1|
(AB032902) Sec61 [Mus musculus]
>gi|7673001|gb|AAF66695.1|AF145253_1 (AF145253) Sec61
alpha isoform 1 [Mus musculus]
Length = 476
Score = 287 bits (726), Expect = 2e-76
Identities = 168/457 (36%), Positives = 272/457 (58%), Gaps = 25/457 (5%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLRVVLAGRNGSI 73
PE+++P++ + KEK +WT + L ++ V +IP++GI D F ++RV+LA G++
Sbjct: 17 PEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTL 76
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+I+QLL G++II++ P+DR + Q++F + + ++ ++V+ G
Sbjct: 77 MELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTG 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G ++ I L+ +QL G+I+++LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 MYGDPS-EMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILK-GDLKGALYRGGTAPDMMAVIATIIVF 251
+ +P T N + + AI+ K L+ A YR P++M +IATI VF
Sbjct: 195 AFSPTT-VNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNL-PNLMNLIATIFVF 252
Query: 252 LVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYANI-----QLWA 303
VV+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL +N+ L A
Sbjct: 253 AVVIYFQGFRVDLPI--KSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSA 310
Query: 304 RVLDRLGHPWLGTFDPTTGN------PVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVI 357
R L LGT+ T+ PVGG Y+ PP S +V+++PV A+VY++ +
Sbjct: 311 RFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLG 370
Query: 358 SSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTV 417
S F W+E++G A+ +A+QL+ + + G R E L +YIP +G L +
Sbjct: 371 SCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHE--LNRYIPTAAAFGGLCI 428
Query: 418 ALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQ 454
++VLADFLGA+G+GTGILL V I+Y+++E +EQ
Sbjct: 429 GALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ 465
>sp|P38377|S61A_CANFA PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT
>gi|346439|pir||A44170 membrane-bound
ribosome-associated translocating polypeptide Sec61p -
dog >gi|164070|gb|AAA30891.1| (M96629) homologue to
sec61 [Canis familiaris]
Length = 476
Score = 286 bits (724), Expect = 4e-76
Identities = 168/457 (36%), Positives = 272/457 (58%), Gaps = 25/457 (5%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLRVVLAGRNGSI 73
PE+++P++ + KEK +WT + L ++ V +IP++GI D F ++RV+LA G++
Sbjct: 17 PEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTL 76
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+I+QLL G++II++ P+DR + Q++F + + ++ ++V+ G
Sbjct: 77 MELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTG 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G ++ I L+ +QL G+I+++LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 MYGDPS-EMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILK-GDLKGALYRGGTAPDMMAVIATIIVF 251
+ +P T N + + AI+ K L+ A YR P++M +IATI VF
Sbjct: 195 AFSPTT-VNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNL-PNLMNLIATIFVF 252
Query: 252 LVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYANI-----QLWA 303
VV+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL +N+ L A
Sbjct: 253 AVVIYFQGFRVDLPI--KSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSA 310
Query: 304 RVLDRLGHPWLGTFDPTTGN------PVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVI 357
R L LGT+ T+ PVGG Y+ PP S +V+++PV A+VY++ +
Sbjct: 311 RFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCHYLSPPESFGSVLEDPVHAVVYIVFMLG 370
Query: 358 SSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTV 417
S F W+E++G A+ +A+QL+ + + G R E L +YIP +G L +
Sbjct: 371 SCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHE--LNRYIPTAAAFGGLCI 428
Query: 418 ALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQ 454
++VLADFLGA+G+GTGILL V I+Y+++E +EQ
Sbjct: 429 GALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ 465
>pir||T02313 endoplasmic reticulum insertion protein F13P17.9 - Arabidopsis
thaliana >gi|3337356|gb|AAC27401.1| (AC004481) putative
protein transport protein SEC61 alpha subunit
[Arabidopsis thaliana]
Length = 475
Score = 284 bits (718), Expect = 2e-75
Identities = 165/462 (35%), Positives = 268/462 (57%), Gaps = 24/462 (5%)
Query: 13 WFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERI-QDYFQFLRVVLAGRNG 71
+ PEV+ + VP +EK ++T ++L ++ V +++P+YGI D F ++RV+LA G
Sbjct: 17 FLPEVQSADRKVPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFYWMRVILASNRG 76
Query: 72 SILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVL 131
+++ LGI PIVT+G+++QLL GS+II++D EDR Q++ + + EA +VL
Sbjct: 77 TVMELGITPIVTSGLVMQLLAGSKIIEVDNNVREDRALLNGAQKLLGILIAIGEAVAYVL 136
Query: 132 GGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRIL 190
G +G VG + A L+ILQL F GII+I LDEL+ K +G+GSGISLFIA + + I+
Sbjct: 137 SGMYGPVG-QLGVGNAILIILQLFFAGIIVICLDELLQKGYGLGSGISLFIATNICESII 195
Query: 191 TRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIA 246
++ +P T I+ G I F I K + L+ A YR P++ ++A
Sbjct: 196 WKAFSPTT----INTGRGAEFEGAVIALFHMLITKSNKVAALRQAFYR-QNLPNVTNLLA 250
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARV 305
T+++FL+V+YF+ RV +P+ + +G YPI+ Y SN+PIIL AL +N+ +++
Sbjct: 251 TVLIFLIVIYFQGFRVVLPVRSKNARGQQGSYPIKLFYTSNMPIILQSALVSNLYFISQL 310
Query: 306 LDR---------LGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTV 356
L R L W + PV G + P S + +P AL Y++ +
Sbjct: 311 LYRKFSGNFFVNLLGQWKESEYSGQSIPVSGLAYLITAPASFSDMAAHPFHALFYIVFML 370
Query: 357 ISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLT 416
+ +F W+E++G AR +A+QL+ + +PG R L++ L +YIP +G +
Sbjct: 371 TACALFSKTWIEVSGSSARDVAKQLKEQQMVMPGHRES--NLQKELNRYIPTAAAFGGVC 428
Query: 417 VALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEM 458
+ + VLADF+GA+G+GTGILL V I+Y+++E +E+ SE+
Sbjct: 429 IGALTVLADFMGAIGSGTGILLAVTIIYQYFETFEKEKASEL 470
>pir||T27227 hypothetical protein Y57G11C.15 - Caenorhabditis elegans
>gi|3881191|emb|CAB16516.1| (Z99281) contains similarity
to Pfam domain: PF00344 (eubacterial secY protein),
Score=21.0, E-value=3.1e-14, N=1~cDNA EST yk42b1.3 comes
from this gene~cDNA EST yk112e4.3 comes from this
gene~cDNA EST EMBL:T00316 comes from this gene~cDNA EST
yk42b1.5>
Length = 473
Score = 282 bits (713), Expect = 8e-75
Identities = 161/469 (34%), Positives = 280/469 (59%), Gaps = 37/469 (7%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLRVVLAGRNGSI 73
PEV +P++ + +EK +WT + L ++ V +IP++GI D F +LRV++A G++
Sbjct: 17 PEVSKPERKIQFREKMLWTAITLFVFLVCCQIPLFGIMSTDSADPFYWLRVIMASNRGTL 76
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+I+QLL G++II++ P+DR + Q++F + + +A ++V+ G
Sbjct: 77 MELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMVITVGQAIVYVMSG 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G ++ I L+++QL G+I+++LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 LYGEPS-EIGAGICLLIVVQLVIAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHIL--KGD----LKGALYRGGTAPDMMAVIA 246
+ +P T TG+ + H+L + D L+ A YR P++M ++A
Sbjct: 195 AFSPATMN------TGRGTEFEGAVIALFHLLATRSDKVRALREAFYRQNL-PNLMNLMA 247
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYANIQLWA 303
T +VF VV+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL +N+ + +
Sbjct: 248 TFLVFAVVIYFQGFRVDLPI--KSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVIS 305
Query: 304 RVL-DRLGHPW----LGTFDPTTGN---PVGGFVLYVIPPRSIFTVIDNPVRALVYLILT 355
++L + G + LGT+ TG P GG Y+ PP S+ + ++P+ ++Y++
Sbjct: 306 QMLAGKFGGNFFINLLGTWSDNTGYRSYPTGGLCYYLSPPESLGHIFEDPIHCIIYIVFM 365
Query: 356 VISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSL 415
+ S F W++++G A+ +A+QL+ + + G R +++ L +YIP +G L
Sbjct: 366 LGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHRE--KSMIHELNRYIPTAAAFGGL 423
Query: 416 TVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQ-----ISEMF 459
+ ++V ADF+GA+G+GTGILL V I+Y+++E +EQ +S MF
Sbjct: 424 CIGALSVTADFMGAIGSGTGILLAVTIIYQYFEIFVKEQQEMGGVSAMF 472
>gi|10946604 Sec61 alpha isoform 2 [Mus musculus]
>gi|7673003|gb|AAF66696.1|AF145254_1 (AF145254) Sec61
alpha isoform 2 [Mus musculus]
Length = 476
Score = 281 bits (712), Expect = 1e-74
Identities = 164/460 (35%), Positives = 269/460 (57%), Gaps = 31/460 (6%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLRVVLAGRNGSI 73
PE+++P++ + +EK +WT + L ++ V +IP++GI D F ++RV+LA G++
Sbjct: 17 PEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTL 76
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+I+QLL G++II++ P+DR + Q++F + + +A ++V+ G
Sbjct: 77 MELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAIVYVMTG 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G ++ I L+I+QL G+I+++LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 MYGDPA-EMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIATI 248
+ +P T I+ G I F + D L+ A YR P++M +IAT+
Sbjct: 195 AFSPTT----INTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNL-PNLMNLIATV 249
Query: 249 IVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYANIQLWARV 305
VF VV+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL +N+ + +++
Sbjct: 250 FVFAVVIYFQGFRVDLPI--KSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQM 307
Query: 306 LD---------RLGHPWLGTFD--PTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLIL 354
L L W P PVGG Y+ PP S+ + ++PV +VY+I
Sbjct: 308 LSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIF 367
Query: 355 TVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGS 414
+ S F W+E++G A+ +A+QL+ + + G R E L +YIP +G
Sbjct: 368 MLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHE--LNRYIPTAAAFGG 425
Query: 415 LTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQ 454
L + ++VLADFLGA+G+GTGILL V I+Y+++E +EQ
Sbjct: 426 LCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ 465
>gb|AAF88109.1|AC021043_2 (AC021043) Putative protein transport protein SEC61 alpha subunit
[Arabidopsis thaliana]
Length = 475
Score = 281 bits (712), Expect = 1e-74
Identities = 164/462 (35%), Positives = 267/462 (57%), Gaps = 24/462 (5%)
Query: 13 WFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERI-QDYFQFLRVVLAGRNG 71
+ PEV+ + +P +EK ++T ++L ++ V +++P+YGI D F ++RV+LA G
Sbjct: 17 FLPEVQSADRKIPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFYWMRVILASNRG 76
Query: 72 SILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVL 131
+++ LGI PIVT+G+++QLL GS+II++D EDR Q++ + EA +VL
Sbjct: 77 TVMELGITPIVTSGLVMQLLAGSKIIEVDNNVREDRALLNGAQKLLWILSAIGEAVAYVL 136
Query: 132 GGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRIL 190
G +G VG + A L+ILQL F GII+I LDEL+ K +G+GSGISLFIA + + I+
Sbjct: 137 SGMYGPVG-QLGVGNAILIILQLFFAGIIVICLDELLQKGYGLGSGISLFIATNICESII 195
Query: 191 TRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIA 246
++ +P T I+ G I F I K + L+ A YR P++ ++A
Sbjct: 196 WKAFSPTT----INTGRGAEFEGAVIALFHMLITKSNKVAALRQAFYR-QNLPNVTNLLA 250
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARV 305
T+++FL+V+YF+ RV +P+ + +G YPI+ Y SN+PIIL AL +N+ +++
Sbjct: 251 TVLIFLIVIYFQGFRVVLPVRSKSARGQQGSYPIKLFYTSNMPIILQSALVSNLYFISQL 310
Query: 306 LDR---------LGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTV 356
L R L W + PV G + P S + +P AL Y++ +
Sbjct: 311 LYRKFSGNFFVNLLGQWKESEYSGQSIPVSGLAYLITAPASFADMAAHPFHALFYIVFML 370
Query: 357 ISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLT 416
+ +F W+E++G AR +A+QL+ + +PG R L++ L +YIP +G +
Sbjct: 371 TACALFSKTWIEVSGSSARDVAKQLKEQQMVMPGHRES--NLQKELNRYIPTAAAFGGVC 428
Query: 417 VALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEM 458
+ + VLADF+GA+G+GTGILL V I+Y+++E +E+ SE+
Sbjct: 429 IGALTVLADFMGAIGSGTGILLAVTIIYQYFETFEKEKASEL 470
>sp|P38379|S61A_PYRSA PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT
>gi|1076193|pir||S51499 sec61 protein - Pyrenomonas
salina >gi|495263|emb|CAA54828.1| (X77805) sec61 protein
[Pyrenomonas salina] >gi|1097096|prf||2113247A sec61
gene [Pyrenomonas salina]
Length = 494
Score = 279 bits (707), Expect = 4e-74
Identities = 166/456 (36%), Positives = 267/456 (58%), Gaps = 29/456 (6%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPE-RIQDYFQFLRVVLAGRNGSI 73
PEV K +P+ EK +WT + + LY V +IP+YGI + D F ++RV+LA G++
Sbjct: 20 PEVSSATKKIPVNEKLLWTSIVVFLYLVCCQIPLYGITNTKSSDPFYWMRVILASNKGTL 79
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+++QLL GS+II +D ED+ +Q Q++ + + E+ +VL G
Sbjct: 80 MELGISPIVTSGLVMQLLAGSKIIDVDQGTKEDKTLFQGAQKLLGILITIGESVAYVLSG 139
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G V D+ A L+I+QL GII+I LDEL+ K +GIGS ISLFIA V + I+ +
Sbjct: 140 MYGDV-KDLGAGNAILIIVQLFTSGIIVICLDELLQKGYGIGSAISLFIATNVCESIVWK 198
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIATI 248
S +P T I+ G + F I K D L+ A YR P++ ++AT+
Sbjct: 199 SFSPTT----INTGRGTEFEGALVALFQLMITKTDKVRALQEAFYR-QNLPNVTNLLATV 253
Query: 249 IVFLVVVYFESMRVEIPL-GYRGVTIRGR-YPIRFLYVSNIPIILTFALYANIQLWARVL 306
+VF++VVYF+ +VE+P+ + + G+ YPI+ Y SN+PIIL AL +N+ +++L
Sbjct: 254 LVFVLVVYFQGFQVELPITPAKSKGMAGQFYPIKLFYTSNMPIILQTALVSNLYFISQIL 313
Query: 307 DR----------LGHPWLGTFDPTTG--NPVGGFVLYVIPPRSIFTVIDNPVRALVYLIL 354
+ LG W +G PVGG Y+ P S ++ +PV AL+Y+I
Sbjct: 314 YKRYPENIIIHILGR-WEEPEMSVSGQMRPVGGIAYYISPLNSFAEIVSDPVHALLYIIF 372
Query: 355 TVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGS 414
+ S +F W++++G A +++QL+ + + GFR +++R L +YIP +G
Sbjct: 373 ILASCALFSKTWIQVSGTSASDVSKQLRDQQMVMKGFRAS--SMQRELNRYIPTAAAFGG 430
Query: 415 LTVALIAVLADFLGALGTGTGILLTVGILYRFYEEI 450
+ + ++++ADF+GA+G+GTGILL V +Y+ +E I
Sbjct: 431 MCIGALSIVADFMGAIGSGTGILLAVTTIYQSWETI 466
>gi|7705736 sec61 homolog [Homo sapiens] >gi|4689112|gb|AAD27765.1|AF077032_1
(AF077032) sec61 homolog [Homo sapiens]
Length = 476
Score = 279 bits (705), Expect = 7e-74
Identities = 162/457 (35%), Positives = 268/457 (58%), Gaps = 25/457 (5%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLRVVLAGRNGSI 73
PE+++P++ + KEK +WT + L ++ V +IP++GI D F ++RV+LA G++
Sbjct: 17 PEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTL 76
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+I+QLL G++II++ P+DR + Q++F + + ++ ++V+
Sbjct: 77 MELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTW 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G ++ I L+ +QL G+I+++LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 MYGDPS-EMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILK-GDLKGALYRGGTAPDMMAVIATIIVF 251
+ +P T N + + AI+ K L+ A YR P++M +IATI VF
Sbjct: 195 AFSPTT-VNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNL-PNLMNLIATIFVF 252
Query: 252 LVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYANIQLWARVLD- 307
VV+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL +N+ + +++L
Sbjct: 253 AVVIYFQGFRVDLPI--KSARYRGQYNSYPIKLFYTSNIPIILQSALVSNLYVISQMLSV 310
Query: 308 --------RLGHPWLGTFD--PTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVI 357
L W P PVGG Y+ PP S+ + ++PV A+VY++ +
Sbjct: 311 RFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVHAVVYIVFMLG 370
Query: 358 SSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTV 417
S F W+E++G A+ +A+QL+ + + G R E L +YIP +G L +
Sbjct: 371 SCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHE--LNRYIPTAAAFGGLCI 428
Query: 418 ALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQ 454
++VLADFLGA+G+GTGILL V I+Y+++E +EQ
Sbjct: 429 GALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ 465
>gb|AAK40996.1| Preprotein translocase secY subunit (secY) [Sulfolobus
solfataricus]
Length = 469
Score = 275 bits (697), Expect = 6e-73
Identities = 161/473 (34%), Positives = 276/473 (58%), Gaps = 25/473 (5%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFL-- 62
D + + ++ P V +PK+ L +K +W+ +A+I+Y ++A P+YGI +F+ L
Sbjct: 5 DSLATLGQYLPAVTKPKEKPSLGQKLVWSLVAVIIYLIMASTPLYGITSA--SFFKNLIL 62
Query: 63 -RVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFM 121
+++ A G++ LGIGPI+TAG+I+Q+L GS++I +DL +P+DR + Q+ +
Sbjct: 63 EQIIFASTTGTLAQLGIGPIITAGLIMQILAGSKLISIDLNDPDDRVKFTEAQKGLAFIF 122
Query: 122 CFLEAAI--WVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGIS 178
+E+A+ +VL + + + IA ++I QL ++++LDEL+ K WG+GSG+S
Sbjct: 123 ILVESALFGYVLARTSTTINASILF-IAGIVIAQLIVATYLILLLDELIQKGWGLGSGVS 181
Query: 179 LFIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYF--IQHILKGDLKGALYRGG 236
LFI AGV + + + + P+ PA+ A+ + +++ L++
Sbjct: 182 LFILAGVMKIMFWDMFGIASVSSQNLPIGFFPALFTALASHSDVLNLIVNTSTKNLFQ-- 239
Query: 237 TAPDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFAL 295
PD++ ++ TI + ++ +Y +M +EIP+ + + IR P+ FLYVS+IP+I L
Sbjct: 240 --PDLVGLVTTIALIIITIYLTTMTIEIPVTSQKLRGIRRTIPLNFLYVSSIPVIFVAVL 297
Query: 296 YANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIP----PRSIFTVIDNPVRALVY 351
++IQL+A + ++ N V G + P P SI+ V+ +P+ AL Y
Sbjct: 298 GSDIQLFASLAS-----YVSPSASNILNTVSGVFFFPPPNSAIPHSIYAVVLDPLGALEY 352
Query: 352 LILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTF 411
++ ++ S++FG LWV++ GLD T A+QL AG++IPG R +P+ +E +L +YI + F
Sbjct: 353 AVVFIVLSILFGILWVDVAGLDPATQAQQLVEAGIEIPGVRNNPKIIEGILARYIYPLAF 412
Query: 412 WGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRR 464
+ S+ V LIAV A LGA GTG GILL V I ++Y +A E+ EM+P L+R
Sbjct: 413 FSSIIVGLIAVFATLLGAYGTGIGILLAVTIAIQYYSLLAYERSLEMYPLLKR 465
>sp|P49978|SECY_SULAC PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|2129436|pir||S59968 secY
protein - Sulfolobus acidocaldarius
>gi|1067199|emb|CAA59382.1| (X85020) preprotein
translocase SecY subunit [Sulfolobus acidocaldarius]
>gi|2052269|emb|CAA69100.1| (Y07778) SecY protein
[Sulfolobus acidocaldarius] >gi|1095811|prf||2109405A
secY gene [Sulfolobus acidocaldarius]
Length = 463
Score = 275 bits (697), Expect = 6e-73
Identities = 156/477 (32%), Positives = 272/477 (56%), Gaps = 31/477 (6%)
Query: 1 MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQ 60
MG D + + + P V +PK L K +WT + LI+Y ++A IP+YG+
Sbjct: 1 MGFMDFLAKMGENLPAVSKPKDKPTLTRKLLWTFIGLIVYLLMASIPLYGVTSSNSFLSN 60
Query: 61 FL--RVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFS 118
FL +++ A G++ LGIGP++T+G+I+Q+LVGS++I +DL E + + ++ +
Sbjct: 61 FLAQQIIFASSQGTLAQLGIGPVITSGLIMQILVGSKLINVDLTTQEGKSKFTQAEKALA 120
Query: 119 VFMCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGI 177
+ +E++++ G F R ++ I ++++QL I+++LDE++ K WG+GSG+
Sbjct: 121 LIFIIVESSLF--GYVFTRATSNILLPI--IVVVQLIIASYIILLLDEMIQKGWGLGSGV 176
Query: 178 SLFIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKG-DLKGALYRGG 236
SLFI AG+ + I I + + VG P + +I G +L+ +
Sbjct: 177 SLFIMAGIMKVIFWNMFG-------IVSVQSQNLPVGFFPLLVSYITSGRNLQEIVLNTS 229
Query: 237 TA----PDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIIL 291
+ PD++ +IAT+ + +++VY + + IP+ + + IR P+ FLYVS+IP+I
Sbjct: 230 STTPYQPDLIGLIATVGLTILIVYLVNTNIYIPVTTQRLRGIRTTVPLNFLYVSSIPVIF 289
Query: 292 TFALYANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPR----SIFTVIDNPVR 347
L A+IQL+A + + + + G + PP+ S++ ++ +PV
Sbjct: 290 VSVLGADIQLFASLANSISNSASGILTDIAN-------AFFFPPQGVPHSVYALVVDPVG 342
Query: 348 ALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIP 407
A +Y + ++ S++FG LW+++ GLD +T A Q+ R+G++IPG R +PR +E +L KYI
Sbjct: 343 AAIYAAVFIVLSIVFGMLWIDVAGLDPKTQAEQMIRSGIEIPGMRTNPRIIEGILSKYIY 402
Query: 408 YVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRR 464
+ F+ SL V LIAV+A FLG GTG G+LL + I ++Y +A E+ EM+P L+R
Sbjct: 403 ALGFFSSLIVGLIAVVATFLGTYGTGVGLLLAITIAMQYYNLLAYERTLEMYPLLKR 459
>sp|Q9UX84|SECY_SULSO PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|6015781|emb|CAB57608.1|
(Y18930) SecY translocase [Sulfolobus solfataricus]
Length = 469
Score = 275 bits (697), Expect = 6e-73
Identities = 161/473 (34%), Positives = 276/473 (58%), Gaps = 25/473 (5%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFL-- 62
D + + ++ P V +PK+ L +K +W+ +A+I+Y ++A P+YGI +F+ L
Sbjct: 5 DSLATLGQYLPAVTKPKEKPSLGQKLVWSLVAVIIYLIMASTPLYGITSA--SFFKNLIL 62
Query: 63 -RVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFM 121
+++ A G++ LGIGPI+TAG+I+Q+L GS++I +DL +P+DR + Q+ +
Sbjct: 63 EQIIFASTTGTLAQLGIGPIITAGLIMQILAGSKLISIDLNDPDDRVKFTEAQKGLAFIF 122
Query: 122 CFLEAAI--WVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGIS 178
+E+A+ +VL + + + IA ++I QL ++++LDEL+ K WG+GSG+S
Sbjct: 123 ILVESALFGYVLARTSTTINASILF-IAGIVIAQLIVATYLILLLDELIQKGWGLGSGVS 181
Query: 179 LFIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYF--IQHILKGDLKGALYRGG 236
LFI AGV + + + + P+ PA+ A+ + +++ L++
Sbjct: 182 LFILAGVMKIMFWDMFGIASVSSQNLPIGFFPALFTALASHSDVLNLIVNTSTKNLFQ-- 239
Query: 237 TAPDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVT-IRGRYPIRFLYVSNIPIILTFAL 295
PD++ ++ TI + ++ +Y +M +EIP+ + + IR P+ FLYVS+IP+I L
Sbjct: 240 --PDLVGLVTTIALIIITIYLTTMTIEIPVTSQKLRGIRRTIPLNFLYVSSIPVIFVAVL 297
Query: 296 YANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIP----PRSIFTVIDNPVRALVY 351
++IQL+A + ++ N V G + P P SI+ V+ +P+ AL Y
Sbjct: 298 GSDIQLFASLAS-----YVSPSASNILNTVSGVFFFPPPNSAIPHSIYAVVLDPLGALEY 352
Query: 352 LILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTF 411
++ ++ S++FG LWV++ GLD T A+QL AG++IPG R +P+ +E +L +YI + F
Sbjct: 353 AVVFIVLSILFGILWVDVAGLDPATQAQQLVEAGIEIPGVRNNPKIIEGILARYIYPLAF 412
Query: 412 WGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRR 464
+ S+ V LIAV A LGA GTG GILL V I ++Y +A E+ EM+P L+R
Sbjct: 413 FSSIIVGLIAVFATLLGAYGTGIGILLAVTIAIQYYSLLAYERSLEMYPLLKR 465
>sp|P79088|S61A_SCHPO PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT
>gi|7493221|pir||T40282 endoplasmic reticulum
translocase sec61 - fission yeast (Schizosaccharomyces
pombe) >gi|1870150|emb|CAA72199.1| (Y11375) SEC61
protein [Schizosaccharomyces pombe]
>gi|1870152|emb|CAA72200.1| (Y11376) SEC61 protein
[Schizosaccharomyces pombe] >gi|2950452|emb|CAA17802.1|
(AL022071) protein transport protein sec61 alpha
subunit. [Schizosaccharomyces pombe]
Length = 479
Score = 269 bits (680), Expect = 6e-71
Identities = 159/470 (33%), Positives = 268/470 (56%), Gaps = 34/470 (7%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPER-IQDYFQFLR 63
D++ + PE+ P++ VP K+K +WTG+ L+++ V++++P+YGI D +LR
Sbjct: 8 DLVKPFAPFLPEIAAPERKVPFKQKMLWTGVTLLIFLVMSQVPLYGIVSSDSSDPLLWLR 67
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
++LA G+++ LGI PIVT+ +++QLLVGS++I++++ DR YQ +Q+ ++ + F
Sbjct: 68 MILAANRGTLMELGISPIVTSSMLVQLLVGSQLIEVNMELKSDREMYQLVQKFLAIIIAF 127
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIA 182
+A +VL G +GR D+ I L+ILQLA +I+++LDEL+ K +G+GSGISLFIA
Sbjct: 128 GQATAYVLTGMYGR-PQDLGAGICLLLILQLAAASLIVLLLDELLQKGYGLGSGISLFIA 186
Query: 183 AGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKG-----ALYRGGT 237
+ I ++ +P T + GA+ F+ + D K A +R G
Sbjct: 187 TINCENIFWKAFSPTT-----YHIANGVQFEGAVINFVYVMFTWDNKAAALYQAFFRSGL 241
Query: 238 A------PDMMAVIATIIVFLVVVYFESMRVEIPL---GYRGVTIRGRYPIRFLYVSNIP 288
P++ AT++VF VV+Y + RVEIP+ +RG R +P++ LY SN P
Sbjct: 242 TSSQIQLPNLWNFFATLLVFGVVIYLQDFRVEIPIRSQKFRG--YRSTFPVKLLYTSNTP 299
Query: 289 IILTFALYANIQLWARVL-DRLGH----PWLGTFDPTTGNPVGGFVLYVIPPRSIFTVID 343
I+L AL +N+ +R+L +R +LG ++ T G Y+ PP S +
Sbjct: 300 IMLQSALTSNLFFASRLLFNRFSSNFLVRFLGVWEQTA---TSGLSYYLSPPASFQDALI 356
Query: 344 NPVRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQ 403
+P+ LVY+ T+ + +F LW+E++G R +A+QL+ L + G R ++ + L+
Sbjct: 357 DPIHTLVYVFFTMFACALFSKLWIEVSGASPRDVAKQLKSQQLVMAGHREG--SMYKELK 414
Query: 404 KYIPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIARE 453
+ IP + V +AV +D LGALG+GT +LL +Y +YE++ +E
Sbjct: 415 RIIPTAAWLSGAVVGALAVASDLLGALGSGTAVLLCTTTIYGYYEQLQKE 464
>sp|Q25147|S61A_HALRO PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT
>gi|506860|dbj|BAA05019.1| (D25536) HRSec61 [Halocynthia
roretzi]
Length = 475
Score = 267 bits (676), Expect = 2e-70
Identities = 157/461 (34%), Positives = 273/461 (59%), Gaps = 34/461 (7%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGI-PERIQDYFQFLRVVLAGRNGSI 73
PE+E+P++ + +EK +WT + L ++ V +IP++GI D F ++RV++A G++
Sbjct: 17 PEIEKPQRKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSESADPFYWMRVIMASNRGTL 76
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+I+QLL G+++I++ P+DR + Q++F + + +A ++V+ G
Sbjct: 77 MELGITPIVTSGLIMQLLAGAKLIEVG-DTPKDRALFNGAQKLFGMIITIGQAVVYVMTG 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G D+ I L+I+QL +I+++LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 MYGDPS-DMGAGICLLIIIQLFIASLIVLLLDELLQKGYGLGSGISLFIATNICETIVWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHIL--KGD----LKGALYRGGTAPDMMAVIA 246
S +P T TG+ + H+L + D L+ A YR P++M + A
Sbjct: 195 SFSPATVN------TGRGTEFEGAVIALFHLLATRSDKVRALREAFYRPNL-PNLMNLSA 247
Query: 247 TIIVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYANIQLWA 303
TI+VF +V+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL + + + +
Sbjct: 248 TILVFGIVIYFQGFRVDLPI--KSARYRGQYSSYPIKLFYTSNIPIILQSALVSGLYVIS 305
Query: 304 RVLDRL--GHPWLGTF----DPTTGNPVGGFVL----YVIPPRSIFTVIDNPVRALVYLI 353
++L G+ ++G D G P + + Y+ PP S F++ +P+ L+Y+
Sbjct: 306 QMLAIRFRGNFFIGLLGVWEDVEGGGPARSYPVALCYYLSPPESFFSMFLDPIHGLLYIT 365
Query: 354 LTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWG 413
+ S F W+E++G A+ +A+QL+ + + G R +++ L +YIP +G
Sbjct: 366 FMLGSCAFFSKTWIEVSGSAAKDVAKQLKEQQMVMRGHRE--KSMIHELNRYIPTAAAFG 423
Query: 414 SLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQ 454
L + ++VLADF+GA+G+GTGILL V I+Y+++E +EQ
Sbjct: 424 GLCIGALSVLADFIGAIGSGTGILLAVTIIYQYFEIFVKEQ 464
>pir||T12065 endoplasmic reticulum insertion protein SEC61 - yeast (Yarrowia
lipolytica) >gi|2076715|emb|CAA72175.1| (Y11322) SEC61
protein [Yarrowia lipolytica]
Length = 471
Score = 264 bits (667), Expect = 2e-69
Identities = 159/468 (33%), Positives = 265/468 (55%), Gaps = 30/468 (6%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLR 63
D++ + PEV+ P++ VP +K MWT + L+++ V++EIP+YGI + D +LR
Sbjct: 8 DLVKPFTPFLPEVQAPERKVPFNQKIMWTAVTLMIFLVMSEIPLYGINSSDKSDALYWLR 67
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
++LA GS++ LGI PIV++G++ QLL G+++I++++ DR YQ Q++F++ +
Sbjct: 68 MMLASNRGSLMELGITPIVSSGMVFQLLGGTQLIEVNMDLKSDRELYQTAQKLFAIILSL 127
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIA 182
+A ++VL G +G D+ + L+I QL +++I+LDEL+ K +G+GSGISLFIA
Sbjct: 128 GQATVYVLTGMYG-PPKDLGVGVCLLLIFQLVLAALVVILLDELLQKGYGLGSGISLFIA 186
Query: 183 AGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHIL--KGDLKGALYRGGT--- 237
+ ++I ++ P T ++ G GAI F+ H+L + D K A+ T
Sbjct: 187 TNICEQIFWKAFAPTT----VNKGRGY-EFEGAIVAFV-HLLFTRKDKKRAIIEAFTRQD 240
Query: 238 APDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFA 294
P+M ++ T+ +F V+Y + RV+IP+ + RG Y PI+ Y SN+PI+L A
Sbjct: 241 LPNMSQLVTTVAIFAAVIYLQGFRVDIPV--KSSKQRGPYGVFPIKLFYTSNLPIMLQSA 298
Query: 295 LYANIQLWAR---------VLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNP 345
L +NI + ++ VL RL W G PV G Y+ PP + + +P
Sbjct: 299 LTSNIFIISQMLFKKFPTNVLVRLLGVWDGREGMQQLFPVSGIAYYMQPPFNAKEALADP 358
Query: 346 VRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKY 405
V+ ++Y+ + +F W+E++G R +A+Q + GL I G R E L++
Sbjct: 359 VKTVIYIAFVLGVCAVFSATWIEISGSSPRDVAKQFKEQGLVIAGRRETSAYKE--LKRI 416
Query: 406 IPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIARE 453
IP +G T+ ++V +D LGAL +GTGIL+ V +Y +YE A+E
Sbjct: 417 IPTAAAFGGATIGALSVASDLLGALSSGTGILMAVTTIYGYYEMAAKE 464
>sp|P78979|S61A_YARLI PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT
Length = 471
Score = 264 bits (667), Expect = 2e-69
Identities = 159/468 (33%), Positives = 265/468 (55%), Gaps = 30/468 (6%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLR 63
D++ + PEV+ P++ VP +K MWT + L+++ V++EIP+YGI + D +LR
Sbjct: 8 DLVKPFTPFLPEVQAPERKVPFNQKIMWTAVTLMIFLVMSEIPLYGINSSDKSDALYWLR 67
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
++LA GS++ LGI PIV++G++ QLL G+++I++++ DR YQ Q++F++ +
Sbjct: 68 MMLASNRGSLMELGITPIVSSGMVFQLLGGTQLIEVNMDLKSDRELYQTAQKLFAIILSL 127
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIA 182
+A ++VL G +G D+ + L+I QL +++I+LDEL+ K +G+GSGISLFIA
Sbjct: 128 GQATVYVLTGMYG-PPKDLGVGVCLLLIFQLVLAALVVILLDELLQKGYGLGSGISLFIA 186
Query: 183 AGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHIL--KGDLKGALYRGGT--- 237
+ ++I ++ P T ++ G GAI F+ H+L + D K A+ T
Sbjct: 187 TNICEQIFWKAFAPTT----VNKGRGY-EFEGAIVAFV-HLLFTRKDKKRAIIEAFTRQD 240
Query: 238 APDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFA 294
P+M ++ T+ +F V+Y + RV+IP+ + RG Y PI+ Y SN+PI+L A
Sbjct: 241 LPNMSQLVTTVAIFAAVIYLQGFRVDIPV--KSSKQRGPYGVFPIKLFYTSNLPIMLQSA 298
Query: 295 LYANIQLWAR---------VLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNP 345
L +NI + ++ VL RL W G PV G Y+ PP + + +P
Sbjct: 299 LTSNIFIISQMLFKKFPTNVLVRLLGVWDGREGMQQLFPVSGIAYYMQPPFNAKEALADP 358
Query: 346 VRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKY 405
V+ ++Y+ + +F W+E++G R +A+Q + GL I G R E L++
Sbjct: 359 VKTVIYIAFVLGVCAVFSATWIEISGSSPRDVAKQFKEQGLVIAGRRETSAYKE--LKRI 416
Query: 406 IPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIARE 453
IP +G T+ ++V +D LGAL +GTGIL+ V +Y +YE A+E
Sbjct: 417 IPTAAAFGGATIGALSVASDLLGALSSGTGILMAVTTIYGYYEMTAKE 464
>emb|CAB90210.1| (AJ238713) SEC61 protein [Candida albicans]
Length = 479
Score = 260 bits (657), Expect = 3e-68
Identities = 153/466 (32%), Positives = 259/466 (54%), Gaps = 26/466 (5%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPER-IQDYFQFLR 63
D++ + PEV P++ V +++ MWT + L+++ V++EIP+YGI D +LR
Sbjct: 8 DLVKPFSPFLPEVIAPERKVQFQQRVMWTIITLLIFLVMSEIPLYGIASSDSSDPLFWLR 67
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
++LA G+++ LGI PIV++G++ QLL G++II +D+ N DR +Q Q++ ++ +
Sbjct: 68 MMLASNRGTLMELGISPIVSSGMLFQLLQGTKIIHVDMQNKNDRETFQTAQKLLAILLAV 127
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIA 182
+A ++VL G +G + + +L+ILQL F I+I+LDEL+ K +G+GSG+SLF A
Sbjct: 128 GQATVYVLTGMYGPPS-SLGVGVCSLLILQLVFASTIVILLDELLQKGYGLGSGVSLFTA 186
Query: 183 AGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHIL--KGDLKGAL---YRGGT 237
+++ ++ P T + K + H+L + D K AL +
Sbjct: 187 TNTCEQVFWKAFAPTTS------TSAKGTEFDGAVVAMFHLLGSRKDKKRALIESFYRPN 240
Query: 238 APDMMAVIATIIVFLVVVYFESMRVEIPL-GYRGVTIRGRYPIRFLYVSNIPIILTFALY 296
P+M ++AT++VF VVY + R+E+P+ R G YPIR Y SNIPI+L AL
Sbjct: 241 LPNMFQLLATLLVFFAVVYLQGFRIELPMKSTRQRGPYGSYPIRLFYTSNIPIMLESALA 300
Query: 297 ANIQLWARVL-----DRLGHPWLGTFDPTTGNPV----GGFVLYVIPPRSIFTVIDNPVR 347
+NI + +++L + L LGT+D G+ GG Y+ PP + + +P++
Sbjct: 301 SNIFIISQLLFMRWPNNLFVKLLGTWDARAGSSQLYANGGLAYYIQPPFNFTDALLDPIK 360
Query: 348 ALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIP 407
+Y+ + S +F W+E++G R +A+Q + GL I G R + + L+K I
Sbjct: 361 TTIYIAFVLGSCAVFSTTWIEISGTSPRDVAKQFKEQGLVIAGHR--DTSAYKELKKIIH 418
Query: 408 YVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIARE 453
+G T+ ++V+ D +G LG+GT ILL V +Y +YE +E
Sbjct: 419 IAAAFGGATIGALSVVCDLMGTLGSGTSILLAVTTIYGYYELAVKE 464
>gi|6323411 membrane component of ER protein translocation apparatus; Sec61p
[Saccharomyces cerevisiae]
>gi|417751|sp|P32915|S61A_YEAST PROTEIN TRANSPORT
PROTEIN SEC61 ALPHA SUBUNIT >gi|280428|pir||A60043
endoplasmic reticulum insertion protein SEC61 - yeast
(Saccharomyces cerevisiae) >gi|4447|emb|CAA44215.1|
(X62340) significant similarity to M.vaneilli SecY
protein [Saccharomyces cerevisiae]
>gi|609428|gb|AAB67276.1| (U19104) Sec61p: membrane
component of ER protein translocation apparatus
[Saccharomyces cerevisiae]
Length = 480
Score = 259 bits (654), Expect = 6e-68
Identities = 155/469 (33%), Positives = 260/469 (55%), Gaps = 31/469 (6%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGI-PERIQDYFQFLR 63
D+ E + PEV P++ VP +K +WTG++L+++ +L +IP+YGI D +LR
Sbjct: 8 DLFKPFESFLPEVIAPERKVPYNQKLIWTGVSLLIFLILGQIPLYGIVSSETSDPLYWLR 67
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
+LA G++L LG+ PI+T+ +I Q L G++++++ + +DR +Q Q+V ++ +
Sbjct: 68 AMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCAIILIL 127
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIA 182
+A + V+ G +G D+ I L+I QL F +I+++LDEL+SK +G+GSGISLF A
Sbjct: 128 GQALVVVMTGNYGAPS-DLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGISLFTA 186
Query: 183 AGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGAL---YRGGTAP 239
++++I R+ P T ++ GK I +F ++ D K AL + P
Sbjct: 187 TNIAEQIFWRAFAPTT----VNSGRGKEFEGAVIAFFHLLAVRKDKKRALVEAFYRTNLP 242
Query: 240 DMMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGR---YPIRFLYVSNIPIILTFALY 296
+M V+ T+ +FL V+Y + R E+P+ R +RG+ YPI+ Y SN PI+L AL
Sbjct: 243 NMFQVLMTVAIFLFVLYLQGFRYELPI--RSTKVRGQIGIYPIKLFYTSNTPIMLQSALT 300
Query: 297 ANIQLWARV---------LDRLGHPWLGTFDPTTGNP---VGGFVLYVIPPRSIFTVIDN 344
+NI L +++ L RL W P T P + G Y+ P S+ + +
Sbjct: 301 SNIFLISQILFQKYPTNPLIRLIGVW--GIRPGTQGPQMALSGLAYYIQPLMSLSEALLD 358
Query: 345 PVRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQK 404
P++ +VY+ + S +F W+E++G R IA+Q + G+ I G R ++ R L+K
Sbjct: 359 PIKTIVYITFVLGSCAVFSKTWIEISGTSPRDIAKQFKDQGMVINGKRE--TSIYRELKK 416
Query: 405 YIPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIARE 453
IP +G T+ ++V +D LG LG+G IL+ +Y +YE A+E
Sbjct: 417 IIPTAAAFGGATIGALSVGSDLLGTLGSGASILMATTTIYGYYEAAAKE 465
>gb|AAF52389.1| (AE003613) CG9539 gene product [Drosophila melanogaster]
Length = 423
Score = 251 bits (634), Expect = 1e-65
Identities = 148/423 (34%), Positives = 252/423 (58%), Gaps = 35/423 (8%)
Query: 57 DYFQFLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRV 116
D F ++RV+LA G+++ LGI PIVT+G+I+QLL G++II++ P+DR + Q++
Sbjct: 7 DPFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKL 65
Query: 117 FSVFMCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGS 175
F + + +A ++V+ G +G ++ + L+I+QL G+I+++LDEL+ K +G+GS
Sbjct: 66 FGMVITIGQAIVYVMTGMYGDPS-EIGAGVCLLIIIQLFAAGLIVLLLDELLQKGYGLGS 124
Query: 176 GISLFIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHIL--KGD----LK 229
GISLFIA + + I+ ++ +P T TG+ + H++ + D L+
Sbjct: 125 GISLFIATNICETIVWKAFSPTT------VTTGRGTEFEGAVIALFHLMATRNDKVRALR 178
Query: 230 GALYRGGTAPDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSN 286
A YR P++M ++AT++VF VV+YF+ RV++P+ + RG+Y PI+ Y SN
Sbjct: 179 EAFYRQNL-PNLMNLLATVLVFAVVIYFQGFRVDLPI--KSARYRGQYSSYPIKLFYTSN 235
Query: 287 IPIILTFALYANIQLWARVLD---------RLGHPW--LGTFDPTTGNPVGGFVLYVIPP 335
IPIIL AL +N+ + +++L L W +G P P+GG Y+ PP
Sbjct: 236 IPIILQSALVSNLYVISQMLAVKFQGNFFINLLGVWADVGGGGPARSYPIGGLCYYLSPP 295
Query: 336 RSIFTVIDNPVRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDP 395
S+ ++ +P+ AL+Y++ + S F W++++G A+ +A+QL+ + + G R +
Sbjct: 296 ESVGHILTDPIHALLYIVFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQHMVMRGHRENS 355
Query: 396 RTLERVLQKYIPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQI 455
E L +YIP +G L + ++V+ADFLGA+G+GTGILL V I+Y+++E +EQ
Sbjct: 356 MIHE--LNRYIPTAAAFGGLCIGALSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ- 412
Query: 456 SEM 458
SEM
Sbjct: 413 SEM 415
>dbj|BAB14148.1| (AK022640) unnamed protein product [Homo sapiens]
Length = 437
Score = 230 bits (581), Expect = 2e-59
Identities = 136/398 (34%), Positives = 229/398 (57%), Gaps = 29/398 (7%)
Query: 15 PEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQ-DYFQFLRVVLAGRNGSI 73
PE+++P++ + +EK +WT + L ++ V +IP++GI D F ++RV+LA G++
Sbjct: 17 PEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTL 76
Query: 74 LTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGG 133
+ LGI PIVT+G+I+QLL G++II++ P+DR + Q++F + + +A ++V+ G
Sbjct: 77 MELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAIVYVITG 135
Query: 134 AFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIAAGVSQRILTR 192
+G ++ I L+I+QL G+I+++LDEL+ K +G+GSGISLFIA + + I+ +
Sbjct: 136 MYGDPA-EMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWK 194
Query: 193 SLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGD----LKGALYRGGTAPDMMAVIATI 248
+ +P T I+ G I F + D L+ A YR P++M +IAT+
Sbjct: 195 AFSPTT----INTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNL-PNLMNLIATV 249
Query: 249 IVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYANIQLWARV 305
VF VV+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL +N+ + +++
Sbjct: 250 FVFAVVIYFQGFRVDLPI--KSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQM 307
Query: 306 LD---------RLGHPWLGTFD--PTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLIL 354
L L W P PVGG Y+ PP S+ + ++PV +VY+I
Sbjct: 308 LSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIF 367
Query: 355 TVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFR 392
+ S F W+E++G A+ +A+QL+ + + G R
Sbjct: 368 MLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHR 405
>gi|8922530 hypothetical protein FLJ10578 [Homo sapiens]
>gi|7022698|dbj|BAA91692.1| (AK001440) unnamed protein
product [Homo sapiens] >gi|10433343|dbj|BAB13955.1|
(AK022027) unnamed protein product [Homo sapiens]
Length = 234
Score = 151 bits (377), Expect = 2e-35
Identities = 85/227 (37%), Positives = 130/227 (56%), Gaps = 18/227 (7%)
Query: 242 MAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRY---PIRFLYVSNIPIILTFALYAN 298
M +IAT+ VF VV+YF+ RV++P+ + RG+Y PI+ Y SNIPIIL AL +N
Sbjct: 1 MNLIATVFVFAVVIYFQGFRVDLPI--KSARYRGQYSSYPIKLFYTSNIPIILQSALVSN 58
Query: 299 IQLWARVLD---------RLGHPWLGTFD--PTTGNPVGGFVLYVIPPRSIFTVIDNPVR 347
+ + +++L L W P PVGG Y+ PP S+ + ++PV
Sbjct: 59 LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH 118
Query: 348 ALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIP 407
+VY+I + S F W+E++G A+ +A+QL+ + + G R E L +YIP
Sbjct: 119 VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHE--LNRYIP 176
Query: 408 YVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQ 454
+G L + ++VLADFLGA+G+GTGILL V I+Y+++E +EQ
Sbjct: 177 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ 223
>gi|6319760 Probable SEC61 protein homolog; Ssh1p [Saccharomyces cerevisiae]
>gi|586395|sp|P38353|SSH1_YEAST SEC SIXTY-ONE PROTEIN
HOMOLOG >gi|626920|pir||S44545 SSH1 protein - yeast
(Saccharomyces cerevisiae) >gi|429128|emb|CAA53646.1|
(X76053) YBR2020-ORF [Saccharomyces cerevisiae]
>gi|536730|emb|CAA85247.1| (Z36152) ORF YBR283c
[Saccharomyces cerevisiae] >gi|1778707|gb|AAB40986.1|
(U05336) sec sixty-one protein homolog [Saccharomyces
cerevisiae] >gi|1587541|prf||2206494J ORF YBR2020
[Saccharomyces cerevisiae]
Length = 490
Score = 147 bits (368), Expect = 2e-34
Identities = 124/475 (26%), Positives = 223/475 (46%), Gaps = 38/475 (8%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPE----RIQDYFQ 60
DI+ I PEVE P + +P +K ++T A ++Y + A+ P+ G+P+ + D
Sbjct: 8 DIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIY-LFAQFPLVGLPKATTPNVNDPIY 66
Query: 61 FLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVF 120
FLR V ++L G+ P +++G+ILQLL G ++IK++ DR +Q+L +VF++
Sbjct: 67 FLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKVIKVNFKIQSDRELFQSLTKVFAIV 126
Query: 121 MCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISL 179
+ I++ G FG D++ L+ QL GI +L E++ K +G SG +
Sbjct: 127 QYVILTNIFIFAGYFGD---DLSVVQIGLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMI 183
Query: 180 FIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILK------GDLKGALY 233
++ ++ + D T GA+ IQ + G + A
Sbjct: 184 INTVVIATNLVADTFGVSQIKVGEDDQT---EAQGALINLIQGLRSKHKTFIGGIISAFN 240
Query: 234 RGGTAPDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGR---YPIRFLYVSNIPII 290
R P++ I + + ++V Y +S+RVE+P+ R RG YPI+ LY + ++
Sbjct: 241 R-DYLPNLTTTIIVLAIAIIVCYLQSVRVELPI--RSTRARGTNNVYPIKLLYTGCLSVL 297
Query: 291 LTFALYANIQLWARVLDRL---GHPW------LGTFDPTTG-NPVGGFVLYVI-PPRSIF 339
++ + I ++A VL +L P +G ++ V F L ++ PP S F
Sbjct: 298 FSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLLAPPTSFF 357
Query: 340 T-VIDNPVRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTL 398
V P+ + Y +++ + F W ++G AR +A + + G+ + G R + +
Sbjct: 358 KGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEFKDQGITLMG--RREQNV 415
Query: 399 ERVLQKYIPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIARE 453
+ L K IP G+ ++LI V+ + LG G GI++ + + E I E
Sbjct: 416 AKELNKVIPIAAVTGASVLSLITVIGESLGLKGKAAGIVVGIAGGFSLLEVITIE 470
>gb|AAF34691.1|AF222906_1 (AF222906) Sec61p [Candida albicans]
Length = 224
Score = 141 bits (353), Expect = 1e-32
Identities = 70/196 (35%), Positives = 124/196 (62%), Gaps = 3/196 (1%)
Query: 5 DIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPER-IQDYFQFLR 63
D++ + PEV P++ V +++ MWT + L+++ V++EIP+YGI D +LR
Sbjct: 8 DLVKPFSPFLPEVIAPERKVQFQQRVMWTIITLLIFLVMSEIPLYGIASSDSSDPLFWLR 67
Query: 64 VVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCF 123
++LA G+++ LGI PIV++G++ QLL G++II +D+ N DR +Q Q++ ++ +
Sbjct: 68 MMLASNRGTLMELGISPIVSSGMLFQLLQGTKIIHVDMQNKNDRETFQTAQKLLAILLAV 127
Query: 124 LEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGSGISLFIA 182
+A ++VL G +G + + +L+ILQL F I+I+LDEL+ K +G+GSG+SLF A
Sbjct: 128 GQATVYVLTGMYGPPS-SLGVGVCSLLILQLVFASTIVILLDELLQKGYGLGSGVSLFTA 186
Query: 183 AGVSQRILTRSLNPLT 198
+++ ++ P T
Sbjct: 187 TNTCEQVFWKAFAPTT 202
>emb|CAB57249.1| (AJ270222) hypothetical protein [Entodinium caudatum]
Length = 190
Score = 116 bits (287), Expect = 7e-25
Identities = 66/177 (37%), Positives = 98/177 (55%), Gaps = 11/177 (6%)
Query: 285 SNIPIILTFALYANIQLWARVLDR-----LGHPWLGTFDPTTGN----PVGGFVLYVIPP 335
SNIPIIL AL +N+ ++++L + L LG ++ PVGG V Y+ PP
Sbjct: 12 SNIPIILQSALVSNLFFFSQILYKRYKHFLPIRILGKWEDVESGGHSIPVGGLVYYISPP 71
Query: 336 RSIFTVIDNPVRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDP 395
SI +P L Y+ +IS F W+E++G +A+ LQ G I G R +
Sbjct: 72 HSILDFAKDPFHTLFYIAFMLISCGFFSKTWIEVSGSGVNDVAKNLQDQGYFIQGMREN- 130
Query: 396 RTLERVLQKYIPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAR 452
++ L++YIP +G + + + + ADFLGA+G+GTGILL V I+Y FYEEI +
Sbjct: 131 -MIKDRLKRYIPIAAVFGGMCIGALTIFADFLGAIGSGTGILLAVTIIYSFYEEIMK 186
>emb|CAC05722.1| (AL391743) protein transport protein sec61 alpha subunit homolog
[Schizosaccharomyces pombe]
Length = 336
Score = 93.6 bits (229), Expect = 4e-18
Identities = 80/317 (25%), Positives = 148/317 (46%), Gaps = 19/317 (5%)
Query: 149 LMILQLAFGGIILIVLDELVSKW-GIGSGISLFIAAGVSQRILTRSLNPLTDP-NIIDPL 206
++ILQ+ GI+ I L E++ K G+GSG L + + + I+ L+ P N
Sbjct: 13 MLILQIFLPGIVCIYLCEIIEKGHGLGSGPVLLLGSHILGNIMWDVLSLHRYPVNESGDS 72
Query: 207 TGKPAIVG-AIPYFIQHILKGDLKGALYRGGTAPDMMAVIATIIVFLVVVYFESMRVEIP 265
+ A+VG A F L+ L+R + + I VF +Y ++R+++P
Sbjct: 73 QYQGALVGFAFNLFSFKNKFSSLRSILFRS-EGLSFVQFLVCIAVFATFMYTLNIRIDVP 131
Query: 266 LGYRGVT-IRGRYPIRFLYVSNIPIILTFALYANIQLWARVLDRL-----------GHPW 313
+ V +R +P++ LY S IP+I +++ +++ ++A L L +
Sbjct: 132 IRSSRVRGVRQNFPLKLLYTSVIPLIYFYSILSHLLVFAYALYSLCPNSLITRLLVQYSP 191
Query: 314 LGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSLIFGFLWVELTGLD 373
+ TF VGG V ++ PP + + +PV ++Y I + ++ F LW+ T
Sbjct: 192 IDTFAEHKLQLVGGLVYFLYPPLGLSEALLHPVHTVIYTITLICITIYFSLLWMNATAGG 251
Query: 374 ARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAVLADFLGALGTG 433
R + + L I G+R T+ + L+K IP + V++++V+A A G
Sbjct: 252 PRDVLLFFKENQLVIAGYRE--ATMLKELEKIIPIAAKLSAFFVSILSVIAGIF-ASTFG 308
Query: 434 TGILLTVGILYRFYEEI 450
G+L+ ++Y +E I
Sbjct: 309 VGVLIASALVYASFEMI 325
>sp|O66491|SECY_AQUAE PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|7444757|pir||H70307
preprotein translocase SecY - Aquifex aeolicus
>gi|2982812|gb|AAC06435.1| (AE000672) preprotein
translocase SecY [Aquifex aeolicus]
Length = 429
Score = 80.8 bits (196), Expect = 3e-14
Identities = 111/475 (23%), Positives = 207/475 (43%), Gaps = 96/475 (20%)
Query: 26 LKEKFMWTGLALILYYVLAEIPVYGI-PERIQDY--------FQFLRVVLAGRNG--SIL 74
L++KF++T L ++Y + + IP+ GI PE ++D+ F + G G ++
Sbjct: 14 LRQKFIFTLLMFVIYRLGSHIPIPGINPEALRDFLKAFEGSVFALYDIFSGGNLGRLTVF 73
Query: 75 TLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGGA 134
LG+ P ++A I++QLL + I L E+ + + ++ ++ A + LG A
Sbjct: 74 ALGVMPYISASIMMQLLTVA-IPSLQRLAKEEGDYGRYKINEYTKYLTLFVATVQSLGIA 132
Query: 135 F---GRV---GVDVT----YAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAAG 184
F G+V G+ V + + +L L G + L+ + + +++ GIG+G SL I AG
Sbjct: 133 FWIRGQVSPKGIPVVENPGISFILITVLTLVAGTMFLVWIADRITEKGIGNGASLIIFAG 192
Query: 185 VSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMAV 244
+ PN A+ F + + GD+ G L ++ +
Sbjct: 193 IVANF----------PN-------------AVIQFYEKVKTGDI-GPL-------TLLLI 221
Query: 245 IATIIVFLV-VVYFESMRVEIPLGYRGVTI-----RGR---YPIRFLYVSNIPIILTFAL 295
IA II +V +VY + IP+ Y G + GR PI+ IPII AL
Sbjct: 222 IALIIAIIVGIVYVQEAERRIPIQYPGRQVGRQLYAGRKTYLPIKINPAGVIPIIFAQAL 281
Query: 296 YANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILT 355
+ + + +L+ + +P++ + + P +IF Y L
Sbjct: 282 ---LLIPSTLLNFVQNPFIKV------------IADMFQPGAIF-----------YNFLY 315
Query: 356 VISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSL 415
V + F + + + ++ +A L +AG IPG R T+ + L++ I + F+G+L
Sbjct: 316 VTFIVFFTYFYTAVL-INPVELAENLHKAGAFIPGVRPGQDTV-KYLERIINRLIFFGAL 373
Query: 416 TVALIAVLADFLGALGT------GTGILLTVGILYRFYEEIAREQISEMFPALRR 464
+++IA++ + GT L+ VG+ + +I I + + + R
Sbjct: 374 FLSVIALIPILISVWFNIPFYFGGTTALIVVGVALDTFRQIETYLIQKKYKSYVR 428
>pir||T39848 protein transport protein sec61 alpha homolog [imported] - fission
yeast (Schizosaccharomyces pombe) (fragment)
>gi|2894273|emb|CAA17071.1| (AL021839) putative protein
transport protein sec61 alpha homolog
[Schizosaccharomyces pombe]
Length = 179
Score = 80.0 bits (194), Expect = 6e-14
Identities = 56/178 (31%), Positives = 88/178 (48%), Gaps = 5/178 (2%)
Query: 2 GARDI--IYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPER-IQDY 58
GAR I I + PEVE PK H+ L EK W +++Y +L+ IPVYG + D
Sbjct: 3 GARFINFIKPLSSLLPEVEGPKTHLELVEKLGWMAGCVVVYQILSIIPVYGAEKTDTLDP 62
Query: 59 FQFLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFS 118
RV+ ++ G+ PI + +LQ+L + I ++ DR +Q Q+V S
Sbjct: 63 INNFRVLDGSSASGLMITGLAPIYLSSFLLQILASKKKIAVNFNLIIDRVLFQNAQKVVS 122
Query: 119 VFMCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSK-WGIGS 175
+ + A +V G +G D+ ++ILQ+ GI+ I L E++ K G+GS
Sbjct: 123 ALLYLILAVTYVSSGYYGSFS-DLGIFRFIMLILQIFLPGIVCIYLCEIIEKGHGLGS 179
>sp|P16336|SECY_BACSU PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|76269|pir||BWBSSY
preprotein translocase secY - Bacillus subtilis
>gi|580926|emb|CAA35712.1| (X51329) SecY protein (AA
1-431) [Bacillus subtilis] >gi|1044984|gb|AAB06819.1|
(L47971) integral membrane protein [Bacillus subtilis]
>gi|1184273|gb|AAB59118.1| (M31102) secY gene product
[Bacillus subtilis] >gi|2632403|emb|CAB11912.1| (Z99104)
preprotein translocase subunit [Bacillus subtilis]
Length = 431
Score = 76.1 bits (184), Expect = 8e-13
Identities = 118/474 (24%), Positives = 192/474 (39%), Gaps = 102/474 (21%)
Query: 26 LKEKFMWTGLALILYYVLAEIPV-YGIPERIQDYFQFLRVVLAGRNG-------SILTLG 77
++ K ++T L LI++ + A IPV Y E +Q Q L G SI +G
Sbjct: 14 IRNKIIFTLLMLIVFRIGAFIPVPYVNAEALQAQSQMGVFDLLNTFGGGALYQFSIFAMG 73
Query: 78 IGPIVTAGIILQLLVGSEIIKLDLANPED---RRFYQALQRVFSVFMCFLEAAIWVLGGA 134
I P +TA II+QLL + K + + RR R F++ + F++A LG +
Sbjct: 74 ITPYITASIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQA----LGMS 129
Query: 135 FG-----------RVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAA 183
+G + GV TY I AL+ L G L+ L E ++ G+G+GIS+ I A
Sbjct: 130 YGFNNLANGMLIEKSGVS-TYLIIALV---LTGGTAFLMWLGEQITSHGVGNGISIIIFA 185
Query: 184 GVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMA 243
G+ I P T I + VG+ HI+K L
Sbjct: 186 GIVSSI------PKTIGQIYE-----TQFVGSNDQLFIHIVKVAL--------------L 220
Query: 244 VIATIIVFLVVVYFESMRVEIPLGYRGVTIRG--------RYPIRFLYVSNIPIILTFAL 295
VIA + V + V++ + +I + Y T R P++ IP+I A
Sbjct: 221 VIAILAVIVGVIFIQQAVRKIAIQYAKGTGRSPAGGGQSTHLPLKVNPAGVIPVIFAVAF 280
Query: 296 YANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDN--PVRALVYLI 353
+ R + GT D T + I DN PV +Y+
Sbjct: 281 L--------ITPRTIASFFGTNDVT---------------KWIQNNFDNTHPVGMAIYVA 317
Query: 354 LTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWG 413
L + + + F+ V + +A L++ G IPG R T +R+ + +TF G
Sbjct: 318 LIIAFTYFYAFVQV-----NPEQMADNLKKQGGYIPGVRPGKMTQDRI-TSILYRLTFVG 371
Query: 414 SLTVALIAVLADFL--------GALGTGTGILLTVGILYRFYEEIAREQISEMF 459
S+ +A+I++L F A GT +L+ VG+ +++ + + +
Sbjct: 372 SIFLAVISILPIFFIQFAGLPQSAQIGGTSLLIVVGVALETMKQLESQLVKRNY 425
>dbj|BAA00495.1| (D00619) SecY [Bacillus subtilis]
Length = 423
Score = 76.1 bits (184), Expect = 8e-13
Identities = 118/474 (24%), Positives = 192/474 (39%), Gaps = 102/474 (21%)
Query: 26 LKEKFMWTGLALILYYVLAEIPV-YGIPERIQDYFQFLRVVLAGRNG-------SILTLG 77
++ K ++T L LI++ + A IPV Y E +Q Q L G SI +G
Sbjct: 6 IRNKIIFTLLMLIVFRIGAFIPVPYVNAEALQAQSQMGVFDLLNTFGGGALYQFSIFAMG 65
Query: 78 IGPIVTAGIILQLLVGSEIIKLDLANPED---RRFYQALQRVFSVFMCFLEAAIWVLGGA 134
I P +TA II+QLL + K + + RR R F++ + F++A LG +
Sbjct: 66 ITPYITASIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQA----LGMS 121
Query: 135 FG-----------RVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAA 183
+G + GV TY I AL+ L G L+ L E ++ G+G+GIS+ I A
Sbjct: 122 YGFNNLANGMLIEKSGVS-TYLIIALV---LTGGTAFLMWLGEQITSHGVGNGISIIIFA 177
Query: 184 GVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMA 243
G+ I P T I + VG+ HI+K L
Sbjct: 178 GIVSSI------PKTIGQIYE-----TQFVGSNDQLFIHIVKVAL--------------L 212
Query: 244 VIATIIVFLVVVYFESMRVEIPLGYRGVTIRG--------RYPIRFLYVSNIPIILTFAL 295
VIA + V + V++ + +I + Y T R P++ IP+I A
Sbjct: 213 VIAILAVIVGVIFIQQAVRKIAIQYAKGTGRSPAGGGQSTHLPLKVNPAGVIPVIFAVAF 272
Query: 296 YANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDN--PVRALVYLI 353
+ R + GT D T + I DN PV +Y+
Sbjct: 273 L--------ITPRTIASFFGTNDVT---------------KWIQNNFDNTHPVGMAIYVA 309
Query: 354 LTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWG 413
L + + + F+ V + +A L++ G IPG R T +R+ + +TF G
Sbjct: 310 LIIAFTYFYAFVQV-----NPEQMADNLKKQGGYIPGVRPGKMTQDRI-TSILYRLTFVG 363
Query: 414 SLTVALIAVLADFL--------GALGTGTGILLTVGILYRFYEEIAREQISEMF 459
S+ +A+I++L F A GT +L+ VG+ +++ + + +
Sbjct: 364 SIFLAVISILPIFFIQFAGLPQSAQIGGTSLLIVVGVALETMKQLESQLVKRNY 417
>sp|P57571|SECY_BUCAI PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|10039163|dbj|BAB13197.1|
(AP001119) preprotein translocase secY subunit [Buchnera
sp. APS]
Length = 437
Score = 71.0 bits (171), Expect = 3e-11
Identities = 101/477 (21%), Positives = 192/477 (40%), Gaps = 105/477 (22%)
Query: 26 LKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFLRVVLAGRNG-------------- 71
LK++ ++ +A+I++ + + IP+ GI I L +L +NG
Sbjct: 19 LKQRIVFLIVAIIVFRIGSFIPIPGIDTTI------LSKILNNQNGTIVDMFNMFSGGAL 72
Query: 72 ---SILTLGIGPIVTAGIILQLL--VGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEA 126
SI LGI P ++A II+QLL V + ++ R R ++ + +++
Sbjct: 73 SRASIFALGIMPYISASIIIQLLTLVYPTLSEIKKEGESGRHRINQYTRYATLILALVQS 132
Query: 127 A--IWVLGGAFG--RVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIA 182
L G + ++ + + I+ L + L+ L EL++++GIG+GIS+ I
Sbjct: 133 IGIAMTLPNIAGIRSIIINTDFYFYLIAIISLVTSTMFLMWLGELITEYGIGNGISIIIF 192
Query: 183 AGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMM 242
G+ + G P+ +G I+ +GDL L+ +
Sbjct: 193 IGI--------------------IAGLPSAIGNT---IEKTRQGDLHILLF-------LF 222
Query: 243 AVIATIIVFLVVVYFESMRVEIPLGYRG--------VTIRGRYPIRFLYVSNIPIILTFA 294
++ V +VV+ E + +I + Y T P++ IP I +
Sbjct: 223 ILLLIFSVIFLVVFMERGQRKIVVHYAQRQQGRRIYETPSTHLPLKINMAGVIPAIFASS 282
Query: 295 LY---ANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVY 351
+ A I W +V H WL +L+ + P +Y
Sbjct: 283 IVLFPATIISWCKV----NHEWLTK------------ILFYLQPNQ-----------FLY 315
Query: 352 LILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTF 411
LIL + + + F F + L + R A L+++G I G R +T + + K + +T
Sbjct: 316 LILYISAIVFFCFFYTGLV-FNPRETADNLKKSGAFISGIRPGEQT-AKYINKIMLRLTL 373
Query: 412 WGSLTVALIAVLADFLGALGT------GTGILLTVGILYRFYEEIAREQISEMFPAL 462
GSL + I ++ +F+ + GT +L+ V ++ F +I +S + ++
Sbjct: 374 VGSLYITFICLIPEFMRSAMNVPFYFGGTSLLIVVVVIIDFITQIQTLIMSNQYESM 430
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.329 0.148 0.450
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 172594881
Number of Sequences: 2977
Number of extensions: 7442367
Number of successful extensions: 22013
Number of sequences better than 1.0e-10: 44
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 21765
Number of HSP's gapped (non-prelim): 47
length of query: 468
length of database: 189,106,746
effective HSP length: 51
effective length of query: 417
effective length of database: 158,583,909
effective search space: 66129490053
effective search space used: 66129490053
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.8 bits)
S2: 167 (69.5 bits)