BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2145 (galE-1) DE:UDP-glucose 4-epimerase (galE-1)
(307 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75143 udp-glucose 4-epimerase (gale-1) PAB2145 - Pyrococcu... 609 e-173
pir||A71183 probable UDP-glucose 4-epimerase - Pyrococcus horiko... 509 e-143
sp|Q57664|GALE_METJA PUTATIVE UDP-GLUCOSE 4-EPIMERASE (GALACTOWA... 269 3e-71
gb|AAB84886.1| (AE000823) UDP-glucose 4-epimerase homolog [Metha... 251 8e-66
pir||C69149 conserved hypothetical protein MTH380 - Methanobacte... 251 8e-66
pir||C72368 hypothetical protein TM0509 - Thermotoga maritima (s... 246 3e-64
dbj|BAB07098.1| (AP001518) UDP-glucose 4-epimerase [Bacillus hal... 235 7e-61
gb|AAG18701.1| (AE004975) UDP-glucose 4-epimerase; GalE2 [Haloba... 231 6e-60
dbj|BAB07368.1| (AP001519) UDP-glucose 4-epimerase [Bacillus hal... 225 6e-58
gb|AAG18703.1| (AE004975) GDP-D-mannose dehydratase; Gmd [Haloba... 221 9e-57
gb|AAK41108.1| UDP-glucose 4-epimerase (galE-2) [Sulfolobus solf... 214 1e-54
emb|CAB57495.1| (Y18930) dTDP-glucose 4,6-dehydratase [Sulfolobu... 214 1e-54
pir||C83136 probable epimerase PA4068 [imported] - Pseudomonas a... 213 3e-54
gb|AAA84870.1| (U34305) ORF2; Method: conceptual translation su... 193 2e-48
pir||T44510 Vi polysaccharide biosynthetic protein homolog [impo... 191 9e-48
pir||T44521 polysaccharide biosynthetic protein [imported] - Shi... 191 9e-48
pir||C70562 probable DTDP-Glucose 4 - Mycobacterium tuberculosis... 186 2e-46
sp|Q04973|VIPB_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPB... 185 7e-46
gb|AAF23998.1| (AF035937) WbpP [Pseudomonas aeruginosa] 182 4e-45
emb|CAA18814.1| (AL023093) putative sugar dehyratase [Mycobacter... 180 2e-44
pir||E69148 UDP-glucose 4-epimerase related protein - Methanobac... 176 2e-43
pir||D70696 probable dtdp-glucose 4 - Mycobacterium tuberculosis... 173 2e-42
dbj|BAB07083.1| (AP001518) spore coat polysaccharide synthesis (... 173 2e-42
pir||C72353 hypothetical protein TM0630 - Thermotoga maritima (s... 172 5e-42
gi|11497973 UDP-glucose 4-epimerase (galE-1) [Archaeoglobus fulg... 171 9e-42
pir||A70392 UDP-glucose-4-epimerase - Aquifex aeolicus >gi|29835... 170 2e-41
pir||H72588 probable dTDP-glucose 4,6-dehydratase APE1180 - Aero... 169 3e-41
gb|AAG18457.1|AF306787_1 (AF306787) AprE [Streptomyces tenebrarius] 169 5e-41
pir||H69105 dTDP-glucose 4,6-dehydratase - Methanobacterium ther... 167 1e-40
pir||T48072 dTDP-glucose 4-6-dehydratase homolog D18 - Arabidops... 166 2e-40
pir||S58282 dTDP-glucose 4-6-dehydratase homolog D18 - Arabidops... 166 2e-40
gb|AAF25549.1|AF109295_4 (AF109295) GalE [Staphylococcus carnosus] 166 4e-40
pir||T00419 dTDP-glucose 4-6-dehydratase homolog T30B22.4 - Arab... 166 4e-40
sp|Q59083|EXOB_AZOBR UDP-GLUCOSE 4-EPIMERASE (UDP-GALACTOSE 4-EP... 165 5e-40
dbj|BAA84593.1| (AB032523) dTDP-glucose 4,6-dehydratase [Strepto... 165 5e-40
pir||D75486 probable UDP-glucose 4-epimerase - Deinococcus radio... 165 5e-40
sp|Q9KDV3|GALE_BACHD UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 164 1e-39
pir||A75008 udp-glucose 4-epimerase (gale-2) PAB1299 - Pyrococcu... 163 2e-39
pir||T35486 probable nucleotide-sugar dehydratase - Streptomyces... 162 4e-39
pir||G82785 dTDP-glucose 4-6-dehydratase XF0611 [imported] - Xyl... 162 6e-39
dbj|BAA25656.1| (AB005901) deduced dNDP-hexose 4,6-dehydratase [... 161 8e-39
pir||H69988 NDP-sugar epimerase homolog ytcB - Bacillus subtilis... 160 2e-38
pir||G70415 nucleotide sugar epimerase - Aquifex aeolicus >gi|29... 160 2e-38
pir||A75303 UDP-glucose 4-epimerase - Deinococcus radiodurans (s... 160 2e-38
pir||T45892 dTDP-glucose 4-6-dehydratase-like protein - Arabidop... 159 3e-38
emb|CAC11160.1| (AL445063) UDP-glucose 4-epimerase related prote... 159 3e-38
dbj|BAB09774.1| (AB016890) dTDP-glucose 4-6-dehydratase [Arabido... 159 3e-38
pir||G70330 ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) rf... 158 7e-38
sp|P26503|EXOB_RHIME UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 158 7e-38
gb|AAC79582.1| (AC005727) putative nucleotide-sugar dehydratase ... 157 1e-37
sp|O84903|GALE_LACCA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 157 2e-37
gb|AAF65473.1|AF253311_1 (AF253311) UDP-galactose 4-epimerase [B... 157 2e-37
gb|AAG19227.1| (AE005019) UDP-glucose 4-epimerase; GalE1 [Haloba... 157 2e-37
gb|AAA68211.1| (L37354) thymidine diphosphoglucose 4,6-dehydrata... 156 3e-37
pir||T45701 dTDP-glucose 4-6-dehydratases-like protein - Arabido... 156 3e-37
emb|CAC14890.1| (AJ295156) d-TDP-glucose dehydratase [Phragmites... 155 4e-37
gb|AAD52168.1|AF144879_7 (AF144879) unknown [Leptospira interrog... 155 8e-37
gb|AAK41125.1| dTDP-Glucose 4,6-dehydratase (rfbB-1) [Sulfolobus... 154 1e-36
emb|CAB57474.1| (Y18930) dTDP-glucose 4,6-dehydratase (rfbB) [Su... 154 1e-36
gb|AAD11505.1| (U60828) UDP-galactose-4-epimerase [Lactococcus l... 154 1e-36
gb|AAC63021.1| (AF082008) UDP-galactose-4-epimerase [Lactococcus... 154 1e-36
gb|AAF50474.1| (AE003556) CG7979 gene product [Drosophila melano... 154 1e-36
pir||T51252 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [imported]... 153 2e-36
gb|AAB47842.1| (U61226) RfbB [Leptospira interrogans] >gi|581432... 153 2e-36
emb|CAA07655.1| (AJ007747) putative nucleotide sugar epimerase/ ... 153 3e-36
gb|AAF73454.1|AF264025_5 (AF264025) putative dTDP-glucose 4, 6-d... 153 3e-36
gb|AAD12971.1| (AF078135) RmlB [Leptospira borgpetersenii] 152 5e-36
gb|AAD44205.1|AF143772_7 (AF143772) GepiA [Mycobacterium avium] 152 7e-36
gb|AAK40511.1| UDP-glucose 4-epimerase (galE-2) [Sulfolobus solf... 152 7e-36
gb|AAD13546.1| (AF080235) NDP-hexose 4,6-dehydratase homolog [St... 152 7e-36
gb|AAD12951.1| (AF078135) unknown [Leptospira borgpetersenii] 151 9e-36
emb|CAB44218.1| (AJ011653) UDP-galactose 4-epimerase [Lactococcu... 151 9e-36
pir||S75089 UDP-glucose 4-epimerase - Synechocystis sp. (strain ... 150 1e-35
emb|CAB61555.1| (AL133171) putative dehydratase [Streptomyces co... 150 1e-35
gb|AAF82605.1| (AF144042) dTDP-glucose 4,6-dehydratase [Streptom... 150 1e-35
pir||H71145 probable UDP-glucose 4-epimerase - Pyrococcus horiko... 150 2e-35
gb|AAK41973.1| dTDP-Glucose 4,6-dehydratase (rfbB-3) [Sulfolobus... 149 3e-35
pir||B75098 dtdp-glucose 4,6-dehydratase (rfbb) PAB0785 - Pyroco... 149 3e-35
dbj|BAB06023.1| (AP001515) nucleotide sugar epimerase (capsular ... 149 3e-35
sp|Q59745|EXOB_RHILT UDP-GLUCOSE 4-EPIMERASE (UDP-GALACTOSE 4-EP... 148 6e-35
pir||I55054 dTDP-D-glucose 4,6-dehydratase - Escherichia coli 148 6e-35
sp|Q58455|YA55_METJA HYPOTHETICAL PROTEIN MJ1055 >gi|2127791|pir... 148 7e-35
emb|CAA77209.1| (Y18523) dTDP-glucose 4,6-dehydratase [Actinopla... 148 7e-35
pir||S49054 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [similarit... 148 1e-34
pir||S75550 dTDP-glucose 4-6-dehydratase - Synechocystis sp. (st... 148 1e-34
pir||C75597 thymidine diphosphoglucose 4,6-dehydratase - Deinoco... 148 1e-34
sp|P21977|GALE_STRTR UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 147 1e-34
sp|P37759|RBB1_ECOLI DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|7437240|pi... 147 1e-34
pir||A69184 UDP-glucose 4-epimerase - Methanobacterium thermoaut... 147 1e-34
gi|7657641 dTDP-D-glucose 4,6-dehydratase [Homo sapiens] >gi|412... 147 2e-34
gb|AAD31800.1|AF128273_3 (AF128273) TDP-glucose-4,6-dehydratase ... 146 2e-34
gb|AAF00211.1|AF164960_7 (AF164960) dNDP-glucose 4,6-dehydratase... 146 3e-34
gb|AAF36926.1|AF221951_2 (AF221951) putative UDP-galactose 4-epi... 146 3e-34
emb|CAB87338.1| (AL163672) UDP-glucose 4-epimerase [Streptomyces... 146 4e-34
emb|CAB95930.1| (AL359989) UDP-glucose 4-epimerase [Streptomyces... 146 4e-34
sp|P33119|GALE_CORDI UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 145 5e-34
pir||S75783 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) - Synechoc... 145 5e-34
gb|AAC68681.1| (AF079762) TDP-glucose-4,6-dehydratase [Streptomy... 145 6e-34
sp|P55180|GALE_BACSU UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 145 8e-34
sp|O65781|GAE2_CYATE UDP-GLUCOSE 4-EPIMERASE GEPI48 (GALACTOWALD... 144 1e-33
sp|P26391|RFBB_SALTY DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|96840|pir|... 144 1e-33
gb|AAF13998.1|AF201913_1 (AF201913) SgcA [Streptomyces globisporus] 144 1e-33
pir||T30873 dNDP-glucose dehydratase - Streptomyces viridochromo... 143 2e-33
gb|AAG09498.1|AF279615_1 (AF279615) dTDP-D-glucose-4,6-dehydrata... 143 2e-33
gb|AAG09509.1|AF279618_1 (AF279618) dTDP-D-glucose-4,6-dehydrata... 143 2e-33
gb|AAG09517.1|AF279620_1 (AF279620) dTDP-D-glucose-4,6-dehydrata... 143 2e-33
pir||T04291 probable UDPglucose 4-epimerase (EC 5.1.3.2) - Arabi... 143 2e-33
pir||S58686 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) graE - Str... 143 3e-33
sp|P96995|GALE_STRMU UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 143 3e-33
pir||G71151 probable dTDP-glucose 4,6-dehydratase - Pyrococcus h... 143 3e-33
pir||T01881 UDPglucose 4-epimerase (EC 5.1.3.2) F8M12.10 - Arabi... 143 3e-33
pir||D81275 probable nucleotide sugar dehydratase Cj1319 [import... 142 4e-33
gb|AAG09530.1|AF279623_1 (AF279623) dTDP-D-glucose-4,6-dehydrata... 142 4e-33
gb|AAG09537.1|AF279625_1 (AF279625) dTDP-D-glucose-4,6-dehydrata... 142 4e-33
gb|AAG26471.1|AF285774_11 (AF285774) putative UDP-glucuronic aci... 142 4e-33
dbj|BAA19633.1| (AB002668) dTDP-D-glucose-4,6-dehydratase [Actin... 142 6e-33
sp|O65780|GAE1_CYATE UDP-GLUCOSE 4-EPIMERASE GEPI42 (GALACTOWALD... 142 6e-33
gb|AAF67513.1|AF170880_20 (AF170880) NovT [Streptomyces spheroides] 142 6e-33
gb|AAF78439.1|AC018748_18 (AC018748) Contains similarity to dTPD... 142 6e-33
sp|P37777|RFBB_SHIFL DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|1073703|pi... 141 7e-33
gb|AAG09506.1|AF279617_1 (AF279617) dTDP-D-glucose-4,6-dehydrata... 141 1e-32
gb|AAG09526.1|AF279622_1 (AF279622) dTDP-D-glucose-4,6-dehydrata... 141 1e-32
gb|AAG09534.1|AF279624_1 (AF279624) dTDP-D-glucose-4,6-dehydrata... 141 1e-32
dbj|BAA82532.1| (AB030032) dTDP-D-glucose 4,6-dehydratase [Actin... 140 2e-32
pir||T00102 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) - Actinoba... 139 4e-32
sp|Q9T0A7|GAE3_ARATH PROBABLE UDP-GLUCOSE 4-EPIMERASE (GALACTOWA... 139 4e-32
dbj|BAA94402.1| (AB041266) dTDP-D-glucose 4,6-dehydratase [Actin... 139 5e-32
gb|AAG09522.1|AF279621_1 (AF279621) dTDP-D-glucose-4,6-dehydrata... 139 5e-32
sp|P55293|RBB2_ECOLI DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|7437235|pi... 138 6e-32
sp|Q45291|GALE_BRELA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 138 8e-32
gb|AAD30579.1|AC007260_10 (AC007260) Similar to dTDP-D-glucose 4... 138 8e-32
pir||T10588 UDPglucose 4-epimerase homolog F9F13.110 - Arabidops... 138 8e-32
gb|AAD50491.1|AF172324_9 (AF172324) UDP-Glc-4-epimerase GalE [Es... 138 1e-31
sp|P39630|SPSJ_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROT... 137 1e-31
sp|P13226|GALE_STRLI UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 137 1e-31
pir||S41534 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) - Shigella... 137 2e-31
pir||T15892 hypothetical protein D2096.4 - Caenorhabditis elegan... 136 2e-31
gb|AAB48319.1| (U29691) CDP-tyvelose epimerase [Yersinia pseudot... 136 4e-31
dbj|BAB07428.1| (AP001519) nucleotide sugar epimerase (biosynthe... 136 4e-31
sp|Q43070|GAE1_PEA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (U... 135 7e-31
gb|AAG21514.1|AC066689_8 (AC066689) UDP-galactose 4-epimerase, p... 135 7e-31
gb|AAC18831.1| (AF059755) nucleotide sugar epimerase [Vibrio vul... 134 9e-31
gb|AAB82632.1| (AC002387) putative nucleotide sugar epimerase [A... 134 1e-30
gb|AAF33465.1| (AF233324) 89% identity with E. coli dTDP-D-gluco... 134 1e-30
gb|AAF78483.1|AC012187_3 (AC012187) Strong similarity to UDPgluc... 134 1e-30
gb|AAG09513.1|AF279619_1 (AF279619) dTDP-D-glucose-4,6-dehydrata... 134 1e-30
emb|CAC11487.1| (AL445064) nucleotide sugar epimerase related pr... 133 3e-30
sp|P14169|RFBE_SALTI CDP-TYVELOSE-2-EPIMERASE >gi|861175|gb|AAB4... 132 4e-30
gb|AAF01814.1|AF187532_10 (AF187532) putative dTDP-glucose-4,6-d... 132 4e-30
pir||G83471 UDP-glucose 4-epimerase PA1384 [imported] - Pseudomo... 132 5e-30
pir||T51106 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [validated... 132 6e-30
pir||T44844 UDPglucose 4-epimerase (EC 5.1.3.2) [imported] - Aci... 131 8e-30
dbj|BAB09155.1| (AB017065) contains similarity to UDP-glucose 4-... 131 1e-29
sp|P55294|RFBB_NEIMB DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|7437244|pi... 131 1e-29
gb|AAD05454.1| (AF064070) putative dTDP-D-glucose 4,6-dehydratas... 131 1e-29
gb|AAC12869.1| (AF044332) dTDP-D-glucose-4,6-dehydratase; RffG [... 129 3e-29
gb|AAD50494.1|AF172324_12 (AF172324) WbnF [Escherichia coli] 129 3e-29
pir||T48867 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [validated... 129 4e-29
gb|AAG12659.1|AC010795_3 (AC010795) uridine diphosphate glucose ... 129 5e-29
gb|AAG29802.1| (AF235050) dTDP-glucose 4,6-dehydratase [Streptom... 129 5e-29
pir||S42430 UDPglucose 4-epimerase (EC 5.1.3.2) galE [similarity... 128 9e-29
gb|AAD05470.1| (AF064070) putative UDP-glucose 4-epimerase [Burk... 128 9e-29
sp|Q57301|GALE_YEREN UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 127 1e-28
emb|CAB05928.1| (Z83335) unknown [Streptococcus pneumoniae] 127 1e-28
gi|6319493 UDP-glucose 4-epimerase; Gal10p [Saccharomyces cerevi... 127 2e-28
pir||F82419 UDP-glucose 4-epimerase VCA0774 [imported] - Vibrio ... 127 2e-28
sp|P09609|GALX_KLULA GAL10 BIFUNCTIONAL PROTEIN [INCLUDES: UDP-G... 127 2e-28
gb|AAD45555.1|U70376_20 (U70376) SpcJ [Streptomyces flavopersicus] 127 2e-28
sp|P37761|RFBB_NEIGO DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|628590|pir... 125 5e-28
sp|Q59678|GALE_PASHA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 125 5e-28
gb|AAA86716.1| (U19895) UDP-glucose 4-epimerase [Neisseria menin... 125 8e-28
gb|AAD23918.1|AF083467_2 (AF083467) UDP-Glucose 4-epimerase [Nei... 125 8e-28
gb|AAG09980.1|AF248584_1 (AF248584) UDP-glucose 4-epimerase [Mor... 125 8e-28
pir||S70744 UDPglucose 4-epimerase (EC 5.1.3.2) - Yersinia enter... 124 1e-27
pir||T00467 UDPglucose 4-epimerase homolog F19I3.8 - Arabidopsis... 123 2e-27
gb|AAF91338.1|AF248583_1 (AF248583) UDP-glucose 4-epimerase [Mor... 123 2e-27
pir||C69148 dTDP-glucose 4,6-dehydratase related protein - Metha... 123 3e-27
sp|P56997|GALE_NEIMA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 123 3e-27
sp|P95780|RMLB_STRMU DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|1813347|db... 122 7e-27
sp|Q59624|GALE_NEIME UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 121 9e-27
sp|P40801|GALX_PACTA GAL10 BIFUNCTIONAL PROTEIN [INCLUDES: UDP-G... 121 1e-26
emb|CAB79762.1| (AL161577) nucleotide sugar epimerase-like prote... 121 1e-26
gb|AAC44971.1| (U09239) dTDP-glucose-4,6-dehydratase [Streptococ... 120 2e-26
emb|CAA40568.1| (X57315) UDP-galactose-4-epimerase [Haemophilus ... 119 4e-26
gb|AAB39936.1| (U76617) UDP-glucose- 4-epimerase [Pasteurella mu... 119 4e-26
sp|P55579|Y4NG_RHISN HYPOTHETICAL 42.8 KD PROTEIN Y4NG >gi|21825... 119 4e-26
gb|AAC38674.1| (AF030359) dTDP-glucose-4,6-dehydratase [Streptoc... 119 4e-26
gb|AAC78676.1| (AF094575) dTDP-glucose-4,6-dehydratase Cps19aN [... 119 4e-26
sp|P24325|GALE_HAEIN UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) ... 118 6e-26
emb|CAB05932.1| (Z83335) dTDP-glucose 4,6-dehydratase [Streptoco... 118 6e-26
emb|CAB65206.1| (AJ007311) RmlB protein [Legionella pneumophila] 118 6e-26
gb|AAD19915.1| (AF105113) dTDP-glucose-4,6-dehydratase [Streptoc... 117 1e-25
gb|AAC38679.1| (AF030360) dTDP-glucose-4,6-dehydratase [Streptoc... 116 2e-25
gb|AAC35922.1| (AF071085) putative dTDP-glucose-4,6-dehydratase ... 116 2e-25
gi|4503891 UDP-galactose-4-epimerase; UDP galactose-4-epimerase;... 113 3e-24
pdb|1EK5|A Chain A, Structure Of Human Udp-Galactose 4-Epimerase... 113 3e-24
gi|11423071 UDP-galactose-4-epimerase [Homo sapiens] 113 3e-24
sp|P37420|RFAD_SALTY ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE (... 110 2e-23
emb|CAA07653.1| (AJ007747) putative nucleotide sugar epimerase/ ... 110 2e-23
pdb|1EQ2|A Chain A, The Crystal Structure Of Adp-L-Glycero-D-Man... 110 2e-23
sp|P17963|RFAD_ECOLI ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE (... 109 4e-23
sp|P45048|RFAD_HAEIN ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE (... 109 4e-23
gb|AAA98766.1| (L76100) ADP-L-glycero-D-manno-heptose-6-epimeras... 109 4e-23
gb|AAG02361.1|AF210249_20 (AF210249) sugar epimerase BlmG [Strep... 108 7e-23
pir||C70840 probable dehydrogenase - Mycobacterium tuberculosis ... 107 2e-22
gb|AAD12165.1| (AF055922) 4-ketoreductase [Streptomyces fradiae]... 107 2e-22
emb|CAB92213.1| (AL356592) NAD-dependent dehydratase. [Streptomy... 106 4e-22
gb|AAC60774.1| (U46859) Fcl [Yersinia enterocolitica (type 0:8)] 105 8e-22
prf||2208414C glucose phosphate thymidylate transferase [Strepto... 105 8e-22
emb|CAB63301.1| (AJ251712) GDP-L-fucose synthetase [Yersinia pse... 105 8e-22
gb|AAC32346.1| (AF061251) fucose synthetase Fcl [Escherichia coli] 104 2e-21
dbj|BAA77731.1| (AB008676) GDP-L-fucose pathway enzyme [Escheric... 104 2e-21
sp|P18645|GALE_RAT UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (U... 102 4e-21
pir||C64627 ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) HP... 100 3e-20
gb|AAB66900.1| (AF013592) ADP-L-glycero-D-mannoheptose-6-epimera... 99 4e-20
sp|P32055|FCL_ECOLI FUCOSE SYNTHETASE >gi|7429918|pir||C64971 hy... 99 6e-20
pdb|1E6U|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reduc... 99 8e-20
pir||D71887 ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) gm... 98 1e-19
pdb|1BWS|A Chain A, Crystal Structure Of Gdp-4-Keto-6-Deoxy-D-Ma... 98 1e-19
gb|AAG24814.1| (AF285085) GDP-L-fucose synthetase [Salmonella ty... 98 1e-19
pdb|1E7Q|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reduc... 98 1e-19
pdb|1E7S|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reduc... 98 1e-19
pir||T15370 hypothetical protein C01F1.3 - Caenorhabditis elegan... 98 2e-19
pir||D55239 cpsB 5'-region hypothetical protein 2 - Escherichia ... 97 3e-19
gb|AAC73015.1| (AC005824) putative dTDP-glucose 4-6-dehydratase ... 97 3e-19
gb|AAD10233.1| (U72147) unknown [Anabaena sp. CA] 96 5e-19
gb|AAF18254.1|AC011438_16 (AC011438) T23G18.6 [Arabidopsis thali... 96 7e-19
pdb|1E7R|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reduc... 96 7e-19
dbj|BAA05020.1| (D25537) HrEpiB [Halocynthia roretzi] 94 3e-18
pir||S74432 hypothetical protein sll1213 - Synechocystis sp. (st... 93 3e-18
gi|9631863 similar to Mycobacterium ORF, corresponds to GenBank ... 87 3e-16
pir||D70393 GDP-D-mannose dehydratase - Aquifex aeolicus >gi|298... 86 6e-16
pir||C81288 probable sugar-nucleotide epimerase/dehydratease Cj1... 86 6e-16
gb|AAF23991.1| (AF035937) WbpV [Pseudomonas aeruginosa] 85 7e-16
gi|9631687 similar to Yersinia GDP-D-mannose dehydratase, corres... 84 2e-15
pir||T05987 hypothetical protein F17M5.120 - Arabidopsis thalian... 80 2e-14
gb|AAB24744.1| (S51942) orf6=nolK [Azorhizobium caulinodans, ORS... 80 4e-14
pir||S74751 CDP-glucose 4,6-dehydratase - Synechocystis sp. (str... 80 4e-14
sp|P33217|NOLK_AZOCA NODULATION PROTEIN NOLK 80 4e-14
gb|AAB49434.1| (U73374) Cap8E [Staphylococcus aureus] 79 6e-14
gb|AAC46088.1| (U81973) Cap5E [Staphylococcus aureus] 79 6e-14
dbj|BAB03206.1| (AB046360) unknown [Actinobacillus actinomycetem... 78 2e-13
pir||S44233 strP protein - Streptomyces glaucescens >gi|581674|e... 76 5e-13
sp|P26397|RFBG_SALTY CDP-GLUCOSE 4,6-DEHYDRATASE >gi|96842|pir||... 76 6e-13
gb|AAD12955.1| (AF078135) unknown [Leptospira borgpetersenii] 76 6e-13
sp|P77398|YFBG_ECOLI HYPOTHETICAL 74.3 KD PROTEIN IN AIS-PMRD IN... 75 1e-12
gb|AAD52172.1|AF144879_11 (AF144879) unknown [Leptospira interro... 75 1e-12
gb|AAF45032.1|AF146601_1 (AF146601) putative GDP-D-mannose dehyd... 74 2e-12
sp|Q06952|GMD1_VIBCH PROBABLE GDP-MANNOSE 4,6-DEHYDRATASE (GDP-D... 74 2e-12
emb|CAA57106.1| (X81324) UDP-glucose 4-epimerase [Saccharomyces ... 73 3e-12
gb|AAF71765.1|AF263912_4 (AF263912) NysDIII [Streptomyces noursei] 73 3e-12
gb|AAD46729.1|AF078736_3 (AF078736) GDP-D-mannose dehydratase [E... 73 4e-12
emb|CAB58336.1| (AL121855) putative epimerase/dehydratase [Strep... 73 5e-12
gb|AAG24813.1| (AF285085) GDP-D-mannose 4,6-dehydratase [Salmone... 73 5e-12
gb|AAF72954.1|AF236052_5 (AF236052) WbjB [Pseudomonas aeruginosa] 71 1e-11
gb|AAD45265.1|AF147795_6 (AF147795) WbjB [Pseudomonas aeruginosa] 71 1e-11
sp|P32054|GM4D_ECOLI GDP-MANNOSE 4,6-DEHYDRATASE (GDP-D-MANNOSE ... 71 2e-11
pdb|1DB3|A Chain A, E.Coli Gdp-Mannose 4,6-Dehydratase 71 2e-11
pir||E82785 GDP-mannose 4,6 dehydratase XF0609 [imported] - Xyle... 71 2e-11
dbj|BAB07437.1| (AP001519) capsular polysaccharide biosynthesis ... 70 3e-11
pir||E71981 probable sugar nucleotide biosynthesis - Helicobacte... 70 4e-11
emb|CAA69124.1| (Y07788) ORF35x7 [Vibrio cholerae] 69 5e-11
sp|P56600|GALX_CANMA GAL10 BIFUNCTIONAL PROTEIN [INCLUDES: UDP-G... 69 5e-11
pir||D82345 UDP-glucose 4-epimerase VC0262 [imported] - Vibrio c... 69 5e-11
sp|Q9VMW9|GMDS_DROME PROBABLE GDP-MANNOSE 4,6 DEHYDRATASE (GDP-D... 69 6e-11
pir||S74433 GDP-D-mannose dehydratase 1 - Synechocystis sp. (str... 69 8e-11
pir||E64525 nodulation protein - Helicobacter pylori (strain 266... 69 8e-11
>pir||D75143 udp-glucose 4-epimerase (gale-1) PAB2145 - Pyrococcus abyssi
(strain Orsay) >gi|5457737|emb|CAB49227.1| (AJ248284)
UDP-glucose 4-epimerase (galE-1) [Pyrococcus abyssi]
Length = 307
Score = 609 bits (1554), Expect = e-173
Identities = 307/307 (100%), Positives = 307/307 (100%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI
Sbjct: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY
Sbjct: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYA 180
GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYA
Sbjct: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYA 180
Query: 181 GVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRET 240
GVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRET
Sbjct: 181 GVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRET 240
Query: 241 TIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGLLETWKW 300
TIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGLLETWKW
Sbjct: 241 TIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGLLETWKW 300
Query: 301 FKSRTLG 307
FKSRTLG
Sbjct: 301 FKSRTLG 307
>pir||A71183 probable UDP-glucose 4-epimerase - Pyrococcus horikoshii
>gi|3258173|dbj|BAA30856.1| (AP000007) 306aa long
hypothetical UDP-glucose 4-epimerase [Pyrococcus
horikoshii]
Length = 306
Score = 509 bits (1297), Expect = e-143
Identities = 243/305 (79%), Positives = 281/305 (91%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M+NKLIV+TGGAGFIGSH+AEALK+ENDV++IDNLYSG+ EN+PEGVKFI ADVRDYESI
Sbjct: 1 MKNKLIVITGGAGFIGSHLAEALKDENDVIIIDNLYSGRIENIPEGVKFIRADVRDYESI 60
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
AE++S ADYVFHEAAQISV+ES++DPVFTEEVNVIGTIN+LRALS+G+GKLIFASSAAVY
Sbjct: 61 AEVISEADYVFHEAAQISVKESIEDPVFTEEVNVIGTINVLRALSQGDGKLIFASSAAVY 120
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYA 180
GEP LPI ED NPISPYG++K++ EHYC+V+ LYG+P VILRYFNVYGPRQSSAYA
Sbjct: 121 GEPKELPITEDTLTNPISPYGITKLAAEHYCRVYQSLYGIPVVILRYFNVYGPRQSSAYA 180
Query: 181 GVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRET 240
GVISIF+ERA++GEPL+IFGDGKQ+RDF+YVKDVVEANILVA+KR A G FNV TG+ET
Sbjct: 181 GVISIFLERAIKGEPLIIFGDGKQTRDFIYVKDVVEANILVAKKRSANGRIFNVATGKET 240
Query: 241 TIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGLLETWKW 300
TI+ELAMKII+++S+SS ILF PRPGDIRRSVA IE+IKKLGFKPRYSLEEGL ET+KW
Sbjct: 241 TILELAMKIIDMTSSSSSILFYPPRPGDIRRSVAKIERIKKLGFKPRYSLEEGLKETFKW 300
Query: 301 FKSRT 305
F SRT
Sbjct: 301 FTSRT 305
>sp|Q57664|GALE_METJA PUTATIVE UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|2129343|pir||D64326 UDPglucose
4-epimerase (EC 5.1.3.2) - Methanococcus jannaschii
>gi|1590951|gb|AAB98196.1| (U67477) UDP-glucose
4-epimerase (galE) [Methanococcus jannaschii]
Length = 305
Score = 269 bits (681), Expect = 3e-71
Identities = 140/304 (46%), Positives = 202/304 (66%), Gaps = 8/304 (2%)
Query: 5 LIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEI 63
+I+VTGGAGFIGSHI + L E N DV+++DNL +G N+ +F+ AD+RD + +I
Sbjct: 1 MILVTGGAGFIGSHIVDKLIENNYDVIILDNLTTGNKNNINPKAEFVNADIRDKDLDEKI 60
Query: 64 -VSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFASSA-AVY 120
+ V H+AAQI+V SV++PV+ ++NV+GTINIL + + + K++FASS AVY
Sbjct: 61 NFKDVEVVIHQAAQINVRNSVENPVYDGDINVLGTINILEMMRKYDIDKIVFASSGGAVY 120
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQS-SAY 179
GEP LP+ E+HP+NP+SPYG+SK GE Y K++ +LYG+ ILRY NVYG RQ
Sbjct: 121 GEPNYLPVDENHPINPLSPYGLSKYVGEEYIKLYNRLYGIEYAILRYSNVYGERQDPKGE 180
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRE 239
AGVISIF+++ L+ + +IFGDG Q+RDFVYV DV +AN++ + E N+GTG+E
Sbjct: 181 AGVISIFIDKMLKNQSPIIFGDGNQTRDFVYVGDVAKANLMALNWK---NEIVNIGTGKE 237
Query: 240 TTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGLLETWK 299
T++ EL I + ++ KPR G++ R DI+K + LG+KP L+EG+
Sbjct: 238 TSVNELFDIIKHEIGFRGEAIYDKPREGEVYRIYLDIKKAESLGWKPEIDLKEGIKRVVN 297
Query: 300 WFKS 303
W K+
Sbjct: 298 WMKN 301
>gb|AAB84886.1| (AE000823) UDP-glucose 4-epimerase homolog [Methanobacterium
thermoautotrophicum]
Length = 316
Score = 251 bits (634), Expect = 8e-66
Identities = 142/312 (45%), Positives = 194/312 (61%), Gaps = 12/312 (3%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVP----EGVKFIEADVR 55
MR+ + VTGG GFIGSH+ + L E N V VID+L +G P+N+ E ++ IE +
Sbjct: 1 MRDMDVAVTGGLGFIGSHLTDELLERGNRVTVIDDLSTGSPDNLRDPHHEDLEIIEGSIN 60
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
D + + ++ DYVFH+AA SV ESV+DP+ VN GT+ +L A S G K++ A
Sbjct: 61 DLD-LEKVFQGKDYVFHQAALASVPESVRDPLRCHRVNATGTLRVLMASSRAGVRKVVNA 119
Query: 115 SSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR 174
S++AVYG +P+RED P+SPY VSKV+GE+YC+VF G+ TV LRYFNVYGPR
Sbjct: 120 STSAVYGNNPEIPLREDARPMPLSPYAVSKVTGEYYCQVFED-QGLETVSLRYFNVYGPR 178
Query: 175 Q--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF 232
Q S YA VI F++ L G I+GDG+QSRDF+YV DVV ANI +AE R + +
Sbjct: 179 QRPDSQYAAVIPRFIDALLSGRSPEIYGDGEQSRDFIYVGDVVRANIFLAESRGS--GVY 236
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEE 292
NV G T+ L I + + ++ + RPGD+R S+AD ++ GF+P LEE
Sbjct: 237 NVAGGSSVTVNRLFDIISGILESDAEPEYLDERPGDVRHSLADTSRLAAAGFRPEVGLEE 296
Query: 293 GLLETWKWFKSR 304
GL+ T +WF R
Sbjct: 297 GLMRTVEWFLER 308
>pir||C69149 conserved hypothetical protein MTH380 - Methanobacterium
thermoautotrophicum (strain Delta H)
Length = 341
Score = 251 bits (634), Expect = 8e-66
Identities = 142/312 (45%), Positives = 194/312 (61%), Gaps = 12/312 (3%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVP----EGVKFIEADVR 55
MR+ + VTGG GFIGSH+ + L E N V VID+L +G P+N+ E ++ IE +
Sbjct: 26 MRDMDVAVTGGLGFIGSHLTDELLERGNRVTVIDDLSTGSPDNLRDPHHEDLEIIEGSIN 85
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
D + + ++ DYVFH+AA SV ESV+DP+ VN GT+ +L A S G K++ A
Sbjct: 86 DLD-LEKVFQGKDYVFHQAALASVPESVRDPLRCHRVNATGTLRVLMASSRAGVRKVVNA 144
Query: 115 SSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR 174
S++AVYG +P+RED P+SPY VSKV+GE+YC+VF G+ TV LRYFNVYGPR
Sbjct: 145 STSAVYGNNPEIPLREDARPMPLSPYAVSKVTGEYYCQVFED-QGLETVSLRYFNVYGPR 203
Query: 175 Q--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF 232
Q S YA VI F++ L G I+GDG+QSRDF+YV DVV ANI +AE R + +
Sbjct: 204 QRPDSQYAAVIPRFIDALLSGRSPEIYGDGEQSRDFIYVGDVVRANIFLAESRGS--GVY 261
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEE 292
NV G T+ L I + + ++ + RPGD+R S+AD ++ GF+P LEE
Sbjct: 262 NVAGGSSVTVNRLFDIISGILESDAEPEYLDERPGDVRHSLADTSRLAAAGFRPEVGLEE 321
Query: 293 GLLETWKWFKSR 304
GL+ T +WF R
Sbjct: 322 GLMRTVEWFLER 333
>pir||C72368 hypothetical protein TM0509 - Thermotoga maritima (strain MSB8)
>gi|4981021|gb|AAD35594.1|AE001727_6 (AE001727)
UDP-glucose 4-epimerase, putative [Thermotoga maritima]
Length = 309
Score = 246 bits (621), Expect = 3e-64
Identities = 141/305 (46%), Positives = 196/305 (64%), Gaps = 10/305 (3%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
I+VTGGAGFIGSH+ + L E V+V+DNL SGK EN+ F E + D E + I
Sbjct: 3 ILVTGGAGFIGSHVVDKLIENGYGVIVVDNLSSGKVENLNRNALFYEQSIEDEEMMERIF 62
Query: 65 S--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGKLIFASSA-AVY 120
S +YVFH AAQ SV SV++P + N+IG++ +L +++ G K IF+S+ A+Y
Sbjct: 63 SLHRPEYVFHLAAQASVAISVREPARDAKTNIIGSLVLLEKSIKYGVKKFIFSSTGGAIY 122
Query: 121 GEPTSL-PIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS-A 178
GE + P E +PISPYG++K S E Y + F + YG+ +LRY NVYGPRQ
Sbjct: 123 GENVKVFPTPETEIPHPISPYGIAKYSTEMYLEFFAREYGLKYTVLRYANVYGPRQDPYG 182
Query: 179 YAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGR 238
AGV++IF ER LRGE + IFGDG+ RD+VYV DVV AN+L EK + E FN+GTGR
Sbjct: 183 EAGVVAIFTERMLRGEEVHIFGDGEYVRDYVYVDDVVRANLLAMEK--GDNEVFNIGTGR 240
Query: 239 ETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLEEGLLET 297
TT+ +L + E++ + ++ PR GD+R+S+ D K K KLG++P+ SLEEGL T
Sbjct: 241 GTTVNQLFKLLKEITGYDKEPVYKPPRKGDVRKSILDYTKAKEKLGWEPKVSLEEGLKLT 300
Query: 298 WKWFK 302
++F+
Sbjct: 301 VEYFR 305
>dbj|BAB07098.1| (AP001518) UDP-glucose 4-epimerase [Bacillus halodurans]
Length = 308
Score = 235 bits (592), Expect = 7e-61
Identities = 136/308 (44%), Positives = 193/308 (62%), Gaps = 10/308 (3%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPE-GVKFIEADVRDYESIA 61
K ++VTGGAGFIGSHI E L + +VVV+DNL +G+ EN+ V F + D+ E +
Sbjct: 3 KKVLVTGGAGFIGSHIVELLLNKGYEVVVVDNLTTGQFENISSFNVPFYKTDIVSSE-LK 61
Query: 62 EIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFASSAA 118
+I S +YV H AAQ+ V +S+ P + E N+IGTIN+L + K+I+ASS A
Sbjct: 62 DIFSKEKPNYVIHHAAQVDVTKSINLPTYDAETNIIGTINLLSCCCQYEVDKVIYASSCA 121
Query: 119 VYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS- 177
VYG+ I ED P+ PIS YG+SK E Y + F+ LYG+ I RY NVYGPRQ+S
Sbjct: 122 VYGDTGDSSITEDFPIQPISFYGISKSVPEMYIRQFHDLYGLKYTIFRYANVYGPRQTSK 181
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
GVISIF +AL+ E +I+G+G+Q+RDF+YV+D+ +AN L + + E FN+GT
Sbjct: 182 GEGGVISIFTTKALKREQPIIYGNGEQTRDFIYVEDIAKANALALD--IGDNEIFNIGTN 239
Query: 238 RETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLLE 296
++T+I EL K+ + + ++ PR GDI S K KK LG+KP SLE G+ E
Sbjct: 240 QKTSINELYNKVNVVRPFAPSAKYTSPREGDILHSRLSYVKAKKILGWKPSVSLERGIQE 299
Query: 297 TWKWFKSR 304
T K+++ +
Sbjct: 300 TLKYYEQK 307
>gb|AAG18701.1| (AE004975) UDP-glucose 4-epimerase; GalE2 [Halobacterium sp. NRC-1]
Length = 328
Score = 231 bits (584), Expect = 6e-60
Identities = 128/316 (40%), Positives = 187/316 (58%), Gaps = 20/316 (6%)
Query: 6 IVVTGGAGFIGSHIAEA-LKEENDVVVIDNLYSGKPENVPE---------------GVKF 49
I+VTGGAGFIG H+AE + +DVVV+DN + + +
Sbjct: 3 ILVTGGAGFIGGHLAERFVSRGHDVVVLDNFDPFYDTRIKDHTVEVCQNLADDGDGSYRL 62
Query: 50 IEADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN- 108
+E DVRD E + E+V+ DYV+H+A Q V SV+DP EVNV GT+N+L A +
Sbjct: 63 VEGDVRDAELVEELVADVDYVYHQAGQAGVRPSVEDPRKYNEVNVDGTLNVLDAARKTEI 122
Query: 109 GKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYF 168
+++FASS++VYG+P LP E HP P+SPYG SK++ E Y + ++Y +PTV LRYF
Sbjct: 123 ERVVFASSSSVYGKPEYLPYDEVHPTTPVSPYGASKLAAERYVCAYSEVYDLPTVALRYF 182
Query: 169 NVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAE 228
VYGPR A IS F+ R L GEP V++GDG Q+RDF Y++DVV+AN + A+
Sbjct: 183 TVYGPRMRPNMA--ISNFVSRCLNGEPPVVYGDGTQTRDFTYIEDVVDANEALLTDDAAD 240
Query: 229 GETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPR 287
GE N+G+ I+ LA +I + + I F++ D + ADI K + LG++P
Sbjct: 241 GEVLNIGSTDNIDILTLAEEIRDQVAPELDIEFAERFEADAEHTHADISKANELLGYEPS 300
Query: 288 YSLEEGLLETWKWFKS 303
++ EG+ E +W+++
Sbjct: 301 RTIREGVQEFVEWYRA 316
>dbj|BAB07368.1| (AP001519) UDP-glucose 4-epimerase [Bacillus halodurans]
Length = 311
Score = 225 bits (567), Expect = 6e-58
Identities = 128/308 (41%), Positives = 193/308 (62%), Gaps = 10/308 (3%)
Query: 6 IVVTGGAGFIGSHIAEAL-KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++VTGGAGFIGSH+ + L E +VV++DNL SG ++V + D+ D E +A++
Sbjct: 4 VLVTGGAGFIGSHLVDLLIAEGTEVVIVDNLSSGSLKHVHPSSHLFKLDILD-ERVADVF 62
Query: 65 S---SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-ALSEGNGKLIFASSAAVY 120
D + H AAQ V SV +P + +VN+ GTI +L + G + +FASSAA+Y
Sbjct: 63 QEHPDIDRIVHLAAQSKVGPSVLNPTYDAQVNIQGTIRLLEFSRKYGVKQFVFASSAAIY 122
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS-AY 179
G +LPIRE+ P P+SPYG SK + E Y K + +LYG+ +LR+ NVYGPRQ++
Sbjct: 123 GPSHTLPIREEFPALPLSPYGTSKYAAEAYVKTYGRLYGLNVHVLRFANVYGPRQTAETE 182
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEA--NILVAEKRRAEGETFNVGTG 237
AGVISIF+E+ L+ E +IFGDGKQ+RDF++V DVV A + L E + +NV TG
Sbjct: 183 AGVISIFIEKLLKNEQPIIFGDGKQTRDFIFVLDVVNAIRSCLETETNQEVDPVYNVSTG 242
Query: 238 RETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLLE 296
+T++ +L ++ + + F + R GDI+ S D +K++K L + PR +L EGL +
Sbjct: 243 LQTSVEDLLKELCAQLNVTYAPAFEQERSGDIKHSCLDQQKLQKHLTWNPRIALNEGLAK 302
Query: 297 TWKWFKSR 304
T ++++R
Sbjct: 303 TIAYYQTR 310
>gb|AAG18703.1| (AE004975) GDP-D-mannose dehydratase; Gmd [Halobacterium sp. NRC-1]
Length = 309
Score = 221 bits (557), Expect = 9e-57
Identities = 128/306 (41%), Positives = 178/306 (57%), Gaps = 11/306 (3%)
Query: 7 VVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPE-----GVKFIEADVRDYESI 60
+VTG AGFIGSH+A AL + DV +DN +G +N+ F EAD+RD + +
Sbjct: 5 LVTGVAGFIGSHLAAALLDRGYDVRGVDNFATGHDQNLEPLRGTGDFSFYEADIRDADLV 64
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFASSAAV 119
A++ + DYVFH+AA SV SV+DPV T +VN GT ++ A E + ++ ASSAA+
Sbjct: 65 ADVTNGVDYVFHQAADSSVPRSVEDPVTTTDVNCTGTATVIDAAREADVDTVVVASSAAI 124
Query: 120 YGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ--SS 177
YG + P E P SPY +SK E +LY + T LRYFN+YGPRQ +
Sbjct: 125 YGSTETFPKVESMTEQPESPYALSKHYTEKLALQASELYDIDTAALRYFNIYGPRQDPNG 184
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
YA VI F+ L GE VI+GDG+QSRDF ++ + ++ANI AE GE FNVG G
Sbjct: 185 DYAAVIPKFISLMLDGERPVIYGDGEQSRDFTFIDNAIQANIRAAE-GDVTGEAFNVGCG 243
Query: 238 RETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLLE 296
T+ EL + +L T ++ PRPGD+R S ADI K ++ L ++P EGL +
Sbjct: 244 GRVTVNELVDVLNDLLDTDIDPIYDDPRPGDVRHSHADISKARELLSYEPEVGFSEGLEQ 303
Query: 297 TWKWFK 302
T +++
Sbjct: 304 TIPYYR 309
>gb|AAK41108.1| UDP-glucose 4-epimerase (galE-2) [Sulfolobus solfataricus]
Length = 310
Score = 214 bits (539), Expect = 1e-54
Identities = 126/306 (41%), Positives = 186/306 (60%), Gaps = 13/306 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
I+++GGAGF+GSH+ EAL E+ + + ++D+L + K N+ + V+FI+ V ++E+ +
Sbjct: 5 ILISGGAGFLGSHLTEALLEKGEEITIVDDLSTAKYFNIRKDVEFIKKKVEEFETEKKY- 63
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGEPT 124
D V H AA+ S E+ ++ PV T N +GT +L + N + I+ SS+ VYG +
Sbjct: 64 ---DVVIHLAARPSPEDYIEHPVDTALSNSLGTYKMLEIARKSNARFIYTSSSEVYGSAS 120
Query: 125 SLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP--RQSS 177
+P E + +NPI S Y SK E +++ Y + T I R FNVYGP R+
Sbjct: 121 IIPTPETYWGYVNPIGIRSCYDESKRFSEALIMAYHRQYKLDTRIQRPFNVYGPGLREDG 180
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
Y V+S F+ +AL+GE + +FGDG Q+R F+Y+ D V+A I + K EGE FN+G+
Sbjct: 181 TYGRVVSRFIYQALKGEDVTVFGDGNQTRAFLYISDWVDATIKLIYKDGLEGEVFNIGSD 240
Query: 238 RETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLEEGLLE 296
+E IIELA II+L+ + S+I + PRP D R ADI K K KLG+ P+ SLEEGL
Sbjct: 241 KEIKIIELANMIIKLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKL 300
Query: 297 TWKWFK 302
T WFK
Sbjct: 301 TINWFK 306
>emb|CAB57495.1| (Y18930) dTDP-glucose 4,6-dehydratase [Sulfolobus solfataricus]
Length = 310
Score = 214 bits (539), Expect = 1e-54
Identities = 126/306 (41%), Positives = 186/306 (60%), Gaps = 13/306 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
I+++GGAGF+GSH+ EAL E+ + + ++D+L + K N+ + V+FI+ V ++E+ +
Sbjct: 5 ILISGGAGFLGSHLTEALLEKGEEITIVDDLSTAKYFNIRKDVEFIKKKVEEFETEKKY- 63
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGEPT 124
D V H AA+ S E+ ++ PV T N +GT +L + N + I+ SS+ VYG +
Sbjct: 64 ---DVVIHLAARPSPEDYIEHPVDTALSNSLGTYKMLEIARKSNARFIYTSSSEVYGSAS 120
Query: 125 SLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP--RQSS 177
+P E + +NPI S Y SK E +++ Y + T I R FNVYGP R+
Sbjct: 121 IIPTPETYWGYVNPIGIRSCYDESKRFSEALIMAYHRQYKLDTRIQRPFNVYGPGLREDG 180
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
Y V+S F+ +AL+GE + +FGDG Q+R F+Y+ D V+A I + K EGE FN+G+
Sbjct: 181 TYGRVVSRFIYQALKGEDVTVFGDGNQTRAFLYISDWVDATIKLIYKDGLEGEVFNIGSD 240
Query: 238 RETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLEEGLLE 296
+E IIELA II+L+ + S+I + PRP D R ADI K K KLG+ P+ SLEEGL
Sbjct: 241 KEIKIIELANMIIKLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKL 300
Query: 297 TWKWFK 302
T WFK
Sbjct: 301 TINWFK 306
>pir||C83136 probable epimerase PA4068 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950266|gb|AAG07455.1|AE004823_1
(AE004823) probable epimerase [Pseudomonas aeruginosa]
Length = 309
Score = 213 bits (536), Expect = 3e-54
Identities = 121/287 (42%), Positives = 176/287 (61%), Gaps = 8/287 (2%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVP---EGVKFIEADVRD 56
M + I++TGGAGFIGSH+ +AL V V+DNL +GK +N+P E V+ +E D D
Sbjct: 1 MFERPILITGGAGFIGSHLTDALLARGYRVRVLDNLSTGKRDNLPLDDERVELLEGDAAD 60
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFAS 115
++A + V H AA SV+ SV DPV T + N I T+N+ A+ E G +++FAS
Sbjct: 61 AATLAAALKGCAAVAHLAAVASVQASVDDPVATHQSNFIATLNLCEAMREQGVKRVVFAS 120
Query: 116 SAAVYGEP-TSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR 174
SAAVYG+ I ED P +P++PY K++ E+Y + + +G+ I R+FNVYGPR
Sbjct: 121 SAAVYGQNGEGTAIDEDTPKSPLTPYASDKLASEYYLDFYRRQHGLEPAIFRFFNVYGPR 180
Query: 175 Q--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF 232
Q SS Y+GVISIF ERAL+G P+ +FGDG+Q+RDF+YV D+V+ + E E
Sbjct: 181 QDPSSPYSGVISIFTERALKGTPITVFGDGEQTRDFIYVADLVDFLVQALEATAVEPGAV 240
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKI 279
NVG R ++ +L +I ++ + + R GDIR S A+ E++
Sbjct: 241 NVGLNRSISLKQLLAEIGQVLGGLPPVTHADARAGDIRHSRANNERL 287
>gb|AAA84870.1| (U34305) ORF2; Method: conceptual translation supplied by author
[Shigella sonnei]
Length = 341
Score = 193 bits (485), Expect = 2e-48
Identities = 121/321 (37%), Positives = 182/321 (56%), Gaps = 24/321 (7%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPEGVK------------FI 50
K ++TG AGFIGS++ E L + N VV+ +DN +G N+ E VK FI
Sbjct: 16 KTWLITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDE-VKTLVSTEQWSRFCFI 74
Query: 51 EADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK 110
E D+RD + +++ D+V H+AA SV S+ DP+ T N+ G +NIL A +
Sbjct: 75 EGDIRDLTTCEQVMKGVDHVLHQAALGSVPRSIVDPITTNATNITGFLNILHAAKNAQVQ 134
Query: 111 -LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
+A+S++ YG+ +LP E++ NP+SPY V+K E Y +V+ + YGV T+ LRYFN
Sbjct: 135 SFTYAASSSTYGDHPALPKVEENIGNPLSPYAVTKYVNEIYAQVYARTYGVKTIGLRYFN 194
Query: 170 VYGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVA-EKRR 226
V+G RQ + AYA VI + L+G+ + I GDG+ SRDF Y+ +V++ NIL A K
Sbjct: 195 VFGRRQDPNGAYAAVIPKWTAAMLKGDDVYINGDGETSRDFCYIDNVIQMNILSALAKDS 254
Query: 227 AEGETFNVGTGRETTIIELAMKIIELSS-----TSSQILFSKPRPGDIRRSVADIEK-IK 280
A+ +NV G TT+ EL+ I + + I + + R GD+R S AD+ K I
Sbjct: 255 AKDNIYNVAVGDRTTLNELSGYIYDELNLIHHIDKLSIKYREFRSGDVRHSQADVTKAID 314
Query: 281 KLGFKPRYSLEEGLLETWKWF 301
L ++P + EGL + W+
Sbjct: 315 LLKYRPNIKIREGLRLSMPWY 335
>pir||T44510 Vi polysaccharide biosynthetic protein homolog [imported] -
Plesiomonas shigelloides >gi|6009649|dbj|BAA85007.1|
(AB025970) ORF2P [Plesiomonas shigelloides]
Length = 345
Score = 191 bits (480), Expect = 9e-48
Identities = 120/321 (37%), Positives = 181/321 (56%), Gaps = 24/321 (7%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPEGVK------------FI 50
K ++TG AGFIGS++ E L + N VV+ +DN +G N+ E VK FI
Sbjct: 20 KTWLITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDE-VKTLVSTEQWSRFCFI 78
Query: 51 EADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK 110
E D+RD + +++ D+V H+AA SV S+ DP+ T N+ G +NIL A +
Sbjct: 79 EGDIRDLTTCEQVMKGVDHVLHQAALGSVPRSIVDPITTNATNITGFLNILHAAKNAQVQ 138
Query: 111 -LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
+A+S++ YG+ +LP E++ NP+SPY V+K E Y +V+ + YG T+ LRYFN
Sbjct: 139 SFTYAASSSTYGDHPALPKVEENIGNPLSPYAVTKYVNEIYAQVYARTYGFKTIGLRYFN 198
Query: 170 VYGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVA-EKRR 226
V+G RQ + AYA VI + L+G+ + I GDG+ SRDF Y+ +V++ NIL A K
Sbjct: 199 VFGRRQDPNGAYAAVIPKWTAAMLKGDDVYINGDGETSRDFCYIDNVIQMNILSALAKDS 258
Query: 227 AEGETFNVGTGRETTIIELAMKIIELSS-----TSSQILFSKPRPGDIRRSVADIEK-IK 280
A+ +NV G TT+ EL+ I + + I + + R GD+R S AD+ K I
Sbjct: 259 AKDNIYNVAVGDRTTLNELSGYIYDELNLIHHIDKLSIKYREFRSGDVRHSQADVTKAID 318
Query: 281 KLGFKPRYSLEEGLLETWKWF 301
L ++P + EGL + W+
Sbjct: 319 LLQYRPNIKIREGLRLSMPWY 339
>pir||T44521 polysaccharide biosynthetic protein [imported] - Shigella sonnei
>gi|6009798|dbj|BAA85072.1| (AB028135) ORF2S [Shigella
sonnei] >gi|10442656|gb|AAG17409.1|AF285970_3 (AF285970)
WbgU [Plesiomonas shigelloides]
>gi|10442667|gb|AAG17419.1|AF285971_3 (AF285971) WbgU
[Shigella sonnei]
Length = 345
Score = 191 bits (480), Expect = 9e-48
Identities = 120/321 (37%), Positives = 181/321 (56%), Gaps = 24/321 (7%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPEGVK------------FI 50
K ++TG AGFIGS++ E L + N VV+ +DN +G N+ E VK FI
Sbjct: 20 KTWLITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDE-VKTLVSTEQWSRFCFI 78
Query: 51 EADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK 110
E D+RD + +++ D+V H+AA SV S+ DP+ T N+ G +NIL A +
Sbjct: 79 EGDIRDLTTCEQVMKGVDHVLHQAALGSVPRSIVDPITTNATNITGFLNILHAAKNAQVQ 138
Query: 111 -LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
+A+S++ YG+ +LP E++ NP+SPY V+K E Y +V+ + YG T+ LRYFN
Sbjct: 139 SFTYAASSSTYGDHPALPKVEENIGNPLSPYAVTKYVNEIYAQVYARTYGFKTIGLRYFN 198
Query: 170 VYGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVA-EKRR 226
V+G RQ + AYA VI + L+G+ + I GDG+ SRDF Y+ +V++ NIL A K
Sbjct: 199 VFGRRQDPNGAYAAVIPKWTAAMLKGDDVYINGDGETSRDFCYIDNVIQMNILSALAKDS 258
Query: 227 AEGETFNVGTGRETTIIELAMKIIELSS-----TSSQILFSKPRPGDIRRSVADIEK-IK 280
A+ +NV G TT+ EL+ I + + I + + R GD+R S AD+ K I
Sbjct: 259 AKDNIYNVAVGDRTTLNELSGYIYDELNLIHHIDKLSIKYREFRSGDVRHSQADVTKAID 318
Query: 281 KLGFKPRYSLEEGLLETWKWF 301
L ++P + EGL + W+
Sbjct: 319 LLKYRPNIKIREGLRLSMPWY 339
>pir||C70562 probable DTDP-Glucose 4 - Mycobacterium tuberculosis (strain H37RV)
>gi|2105060|emb|CAB08849.1| (Z95436) rmlB2
[Mycobacterium tuberculosis]
Length = 314
Score = 186 bits (468), Expect = 2e-46
Identities = 119/310 (38%), Positives = 172/310 (55%), Gaps = 14/310 (4%)
Query: 7 VVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVK-----FIEADV--RDYE 58
+VTG AGFIGS + + L + + VV +DN +G+ N+ F+EAD+ D
Sbjct: 4 LVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTADLH 63
Query: 59 SIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSA 117
+I E + VFH AAQI V SV DP F VNVIGT+ + A + G K++ SS
Sbjct: 64 AILE-QHRPEVVFHLAAQIDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSG 122
Query: 118 -AVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQS 176
++YG P P E P +P SPY KV+GE Y F LYG+ + NVYGPRQ
Sbjct: 123 GSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQD 182
Query: 177 -SAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
AGV++IF + L G+P +FGDG +RD+V+V DVV+A + V+ G FN+G
Sbjct: 183 PHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSAD-VGGGLRFNIG 241
Query: 236 TGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGL 294
TG+ET+ +L + F PR GD++RS DI ++ LG++P+ L +G+
Sbjct: 242 TGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGV 301
Query: 295 LETWKWFKSR 304
T ++F+ +
Sbjct: 302 RRTVEYFRHK 311
>sp|Q04973|VIPB_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPB/TVIC
>gi|1361288|pir||C36892 Vi polysaccharide biosynthetic
protein vipB - Salmonella typhi
>gi|47961|emb|CAA47992.1| (X67785) wcdB; ORF3 in
citation [1] [Salmonella typhi]
>gi|426446|dbj|BAA03193.1| (D14156) WcdB protein
[Salmonella typhi]
Length = 348
Score = 185 bits (464), Expect = 7e-46
Identities = 113/331 (34%), Positives = 181/331 (54%), Gaps = 30/331 (9%)
Query: 1 MRNKLIV------VTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPE-------- 45
+R KL++ +TG AGFIGS + E L N V+ +DN +G N+ +
Sbjct: 7 LRTKLVLAPKRWLITGVAGFIGSGLLEELLFLNQTVIGLDNFSTGYQHNLDDVRTSVSEE 66
Query: 46 ---GVKFIEADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR 102
FI+ D+R + + + DYV H+AA SV S+KDP+ T N+ G +N+L
Sbjct: 67 QWSRFIFIQGDIRKFTDCQKACKNVDYVLHQAALGSVPRSLKDPIATNSANIDGFLNMLT 126
Query: 103 ALSEGN-GKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVP 161
A + + +A+S++ YG+ LP E+ P+SPY V+K E Y VF + Y
Sbjct: 127 AARDAHVSSFTYAASSSTYGDHPDLPKIEERIGRPLSPYAVTKYVNELYADVFARSYEFN 186
Query: 162 TVILRYFNVYGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANI 219
+ LRYFNV+G RQ + AY+ VI ++ L+ EP+ I GDG SRDF Y+++V++AN+
Sbjct: 187 AIGLRYFNVFGRRQNPNGAYSAVIPRWILSLLKDEPIYINGDGSTSRDFCYIENVIQANL 246
Query: 220 LVAEKR--RAEGETFNVGTGRETTIIEL------AMKIIELSSTSSQILFSKPRPGDIRR 271
L A ++ + +NV G T++ EL + + + ++ ++ R GD++
Sbjct: 247 LSATTNDLASKNKVYNVAVGDRTSLNELYYLIRDGLNLWRNEQSRAEPIYKDFRDGDVKH 306
Query: 272 SVADIEKIKK-LGFKPRYSLEEGLLETWKWF 301
S ADI KIK L ++P + ++EGL +T KW+
Sbjct: 307 SQADITKIKTFLSYEPEFDIKEGLKQTLKWY 337
>gb|AAF23998.1| (AF035937) WbpP [Pseudomonas aeruginosa]
Length = 341
Score = 182 bits (458), Expect = 4e-45
Identities = 111/320 (34%), Positives = 174/320 (53%), Gaps = 22/320 (6%)
Query: 4 KLIVVTGGAGFIGSHIAEAL-KEENDVVVIDNLYSGKPENVPE-----------GVKFIE 51
K+ ++TG AG IGS++ E L K + VV +DN +G N+ E KFI+
Sbjct: 17 KVWLITGVAGSIGSNLLETLLKLDQKVVGLDNFATGHQRNLDEVRSLASEKQWSNFKFIQ 76
Query: 52 ADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK- 110
D+R+ + + DYV H+AA SV S+ DP+ + N+ G +N+L A + +
Sbjct: 77 GDIRNLDDCNNACAGVDYVLHQAALGSVPRSINDPITSNATNIDGFLNMLIAARDAKVQS 136
Query: 111 LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
+A+S++ YG+ LP ED P+SPY V+K E Y VF + YG T+ LRYFNV
Sbjct: 137 FTYAASSSTYGDHPGLPKVEDTIGKPLSPYAVTKYVNELYADVFSRCYGFSTIGLRYFNV 196
Query: 171 YGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEK-RRA 227
+G RQ + AYA VI + ++G+ + I GDG+ SRDF Y+++ V+AN+L A A
Sbjct: 197 FGRRQDPNGAYAAVIPKWTSSMIQGDDVYINGDGETSRDFCYIENTVQANLLAATAGLDA 256
Query: 228 EGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKP-----RPGDIRRSVADIEKIKK- 281
+ +N+ G T++ +L + + + + +P R GD+R S+ADI K K
Sbjct: 257 RNQVYNIAVGGRTSLNQLFFALRDGLAENGVSYHREPVYRDFREGDVRHSLADISKAAKL 316
Query: 282 LGFKPRYSLEEGLLETWKWF 301
LG+ P+Y + G+ W+
Sbjct: 317 LGYAPKYDVSAGVALAMPWY 336
>emb|CAA18814.1| (AL023093) putative sugar dehyratase [Mycobacterium leprae]
Length = 319
Score = 180 bits (451), Expect = 2e-44
Identities = 116/309 (37%), Positives = 167/309 (53%), Gaps = 14/309 (4%)
Query: 7 VVTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPE-----GVKFIEADV--RDYE 58
+VTG AGFIGS + + L + VV +DN +G N+ + F+EAD+ D +
Sbjct: 9 LVTGAAGFIGSTLVDRLLADGHTVVGLDNFATGHAANLEHLASTPALAFVEADIVTADLQ 68
Query: 59 SIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSA 117
+I + + VFH AAQI V SV DP F VNVIGT+ + A G K++ SS
Sbjct: 69 TILD-EHRPEVVFHLAAQIDVRHSVVDPQFDASVNVIGTVRLAEAARHTGVRKIVHTSSG 127
Query: 118 -AVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQS 176
++YG P+ P E P +P SPY KV+GE Y F L G+ + NVYGPRQ
Sbjct: 128 GSIYGTPSQYPTPETVPTDPTSPYAAGKVAGEIYLNTFRHLCGLDCSHIAPANVYGPRQD 187
Query: 177 S-AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
AGV++IF++ L P +FGDG +RD+V+V DVV+A + A G+ FN+G
Sbjct: 188 PYGEAGVVAIFVQALLSDRPTKVFGDGTHTRDYVFVDDVVDA-FIKASGDAGGGQRFNIG 246
Query: 236 TGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIE-KIKKLGFKPRYSLEEGL 294
TG ET+ +L + F PR GD++RS DI LG+ P+ L++G+
Sbjct: 247 TGIETSDRQLHTAVSAAVGGPDDPEFHPPRLGDLKRSCLDIGLATTVLGWSPQVQLDDGV 306
Query: 295 LETWKWFKS 303
T ++F++
Sbjct: 307 RRTVEYFRA 315
>pir||E69148 UDP-glucose 4-epimerase related protein - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621436|gb|AAB84881.1| (AE000823) UDP-glucose
4-epimerase related protein [Methanobacterium
thermoautotrophicum]
Length = 332
Score = 176 bits (443), Expect = 2e-43
Identities = 109/308 (35%), Positives = 178/308 (57%), Gaps = 10/308 (3%)
Query: 4 KLIVVTGGAGFIGSHIAEAL-KEENDVVVIDNLYSGKPENVPE--GVKFIEADVRDYESI 60
K ++VTGGAG +GS++ L K +V+++DNL S N+PE ++F++ D+ D E +
Sbjct: 12 KCVLVTGGAGCVGSNLTGNLAKAGANVIILDNLSSSYEWNIPEYENIEFVKGDILDDEVL 71
Query: 61 AEIVSSA-DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-ALSEGNGKLIFASSAA 118
+ DYVFH AA + + SV +P VN +G + +L A G + +++SS
Sbjct: 72 KRVFKERPDYVFHLAAHFANQNSVDNPEKDLLVNGLGILKVLEYAQLVGVERFVYSSSGC 131
Query: 119 -VYGEPTSLPIRE-DHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ- 175
VYG + +P E D ++ +PY V+K+ GE Y F+ LY +P V R+FNV+GP +
Sbjct: 132 GVYGLDSKIPFEEHDISISLHTPYQVTKLLGELYTNYFHNLYEMPIVNARFFNVFGPGEV 191
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
Y VI F A+ +PL I GDG ++RD+ +V+D+V + + +R A GE N+G
Sbjct: 192 PGKYRNVIPNFFYWAMNQQPLPITGDGSETRDWTFVEDIVRGLMAMGVRREAIGEAINLG 251
Query: 236 TGRETTIIELAMKIIELSSTSSQILFSKPRPGDIR-RSVADIEKIKK-LGFKPRYSLEEG 293
+G E +IE+A I EL+ + +++ R D + R ++ I+K ++ L ++P+ S EG
Sbjct: 252 SGTEHQVIEMAGIINELTENPAGVVYRPRRDWDAKTRLLSSIDKARRLLDYEPQVSFREG 311
Query: 294 LLETWKWF 301
L T +WF
Sbjct: 312 LERTHRWF 319
>pir||D70696 probable dtdp-glucose 4 - Mycobacterium tuberculosis (strain H37RV)
>gi|1552867|emb|CAB02463.1| (Z80343) epiB [Mycobacterium
tuberculosis]
Length = 326
Score = 173 bits (434), Expect = 2e-42
Identities = 101/310 (32%), Positives = 163/310 (52%), Gaps = 13/310 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVP-----EGVKFIEADVRDYES 59
I+VTGGAGF GSH+ E+L V V+D N+ + FI V D ++
Sbjct: 3 ILVTGGAGFQGSHLTESLLANGHWVTVLDKSSRNAVRNMQGFRSHDRAAFISGSVTDGQT 62
Query: 60 IAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAV 119
I V VFH AA ++V++S+ DP E NV+GT +L A+ +LI+ S+ V
Sbjct: 63 IDRAVRDHHVVFHLAAHVNVDQSLGDPESFLETNVMGTYRVLEAVRRYRNRLIYVSTCEV 122
Query: 120 YGEPTSLP----IREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
YG+ +L + E L P SPYG SK + + C +++ YG+ I+R FN++G RQ
Sbjct: 123 YGDGHNLKEGERLDEHAELKPNSPYGASKAAADRLCYSYFRSYGLDVTIVRPFNIFGVRQ 182
Query: 176 SSA-YAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNV 234
+ + +I + + + GE L IFG G +RD++YV D+V A LV G+ N
Sbjct: 183 KAGRFGALIPRLVRQGINGEGLTIFGAGSATRDYLYVSDIVGAYNLVLRTPTLRGQAINF 242
Query: 235 GTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGL 294
+G++T + ++ + + ++I RPG+++R ADI K +GF+P+ + +G+
Sbjct: 243 ASGKDTRVRDIVEYVAD--KFGARIEHRDARPGEVQRFPADISLAKSIGFQPQVEIWDGI 300
Query: 295 LETWKWFKSR 304
W K +
Sbjct: 301 DRYINWAKDQ 310
>dbj|BAB07083.1| (AP001518) spore coat polysaccharide synthesis (dTDP glucose 4,
6-dehydratase) [Bacillus halodurans]
Length = 321
Score = 173 bits (434), Expect = 2e-42
Identities = 112/317 (35%), Positives = 169/317 (52%), Gaps = 18/317 (5%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEENDVVVIDNL----YSGKPENVPEGVK-----FIEAD 53
+K I+VTGGAGFIGSH EAL + I N+ Y+GK EN+ K FI AD
Sbjct: 2 SKQILVTGGAGFIGSHFIEALLQHKPTYHITNVDVLTYAGKIENMSGFTKHPNYRFISAD 61
Query: 54 VRDYESIAEIVSSA-DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-L 111
+ D + + D + H AA+ V+ S+ +P+ E N++GT N+L A+ +G K +
Sbjct: 62 IGDADQLLGAFDRTYDVIVHFAAETHVDRSIHNPMVFLETNILGTHNLLLAVLKGYAKKI 121
Query: 112 IFASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
++ S+ VYG +P E PL +PY SK G+ + FY+ Y P +I R N
Sbjct: 122 LYISTDEVYGSLGMKDVPFTEQSPLAANNPYSASKAGGDLLARSFYKTYQAPVIITRCSN 181
Query: 170 VYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG 229
YGPRQ +I + AL + + ++GDG Q RD++YV D A + E G
Sbjct: 182 NYGPRQDK--EKLIPKIIANALTNKKIPLYGDGLQIRDWLYVTDHCRALTTIMEHGEI-G 238
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQIL-FSKPRPGDIRRSVADIEKI-KKLGFKPR 287
E +N+G G E T +E+ +I+ + ++ + R G RR + KI K+LG++P
Sbjct: 239 EIYNIGGGNERTNLEITKQILNILGKDHDLINHVEDRKGHDRRYAINWGKIHKQLGWRPM 298
Query: 288 YSLEEGLLETWKWFKSR 304
+ E+GL ET +W+KSR
Sbjct: 299 VAFEDGLAETVQWYKSR 315
>pir||C72353 hypothetical protein TM0630 - Thermotoga maritima (strain MSB8)
>gi|4981151|gb|AAD35714.1|AE001737_7 (AE001737)
nucleotide sugar epimerase, putative [Thermotoga
maritima]
Length = 346
Score = 172 bits (431), Expect = 5e-42
Identities = 115/314 (36%), Positives = 175/314 (55%), Gaps = 17/314 (5%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGK----PENVPEGVKFIEADVRDYE 58
K ++VTGGAG +GS++ L + V+VIDNL SG P++ P + FIE D+ +
Sbjct: 14 KRVLVTGGAGAVGSNLVRRLLDLGAFVIVIDNLSSGYTWLLPQDAPN-LLFIEGDITNDV 72
Query: 59 SIAEIVSSA-DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKL---IFA 114
+ + + + +FH AA + + SV P VN GT+ +L + GK+ ++A
Sbjct: 73 DLKRVFNEEPEIIFHLAAFFANQNSVDYPEKDLWVNGFGTLKLLE-YTRIYGKVERFVYA 131
Query: 115 SSA-AVYGEPTSLPIREDHPLNP--ISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
SS ++Y +P +ED P++ +PY ++K GE YC FY++Y +P R+FN +
Sbjct: 132 SSGCSIYPSDAPMPFKEDLPISSWMSTPYQITKALGELYCNYFYKMYDIPITKARFFNSF 191
Query: 172 GPRQ-SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
GP + Y VI F+ A+ G+PL I G G+++RDF YV D+V+ + + R A GE
Sbjct: 192 GPGEVPGQYRNVIPNFIYWAMLGKPLPITGTGEETRDFTYVGDIVDGLLRMGYYREAIGE 251
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIR-RSVADIEKIKK-LGFKPRY 288
FN+ GRE I LA K+ EL+ ++ I+F R D + R +A EK KK LGF P
Sbjct: 252 AFNLAAGREVKIKYLAEKVNELTGNTAGIVFKPRRKWDTKPRMLASNEKAKKVLGFNPDP 311
Query: 289 SLEEGLLETWKWFK 302
+ L ET +WFK
Sbjct: 312 DFDGRLAETVEWFK 325
>gi|11497973 UDP-glucose 4-epimerase (galE-1) [Archaeoglobus fulgidus]
>gi|7437251|pir||A69295 UDP-glucose 4-epimerase (galE-1)
homolog - Archaeoglobus fulgidus
>gi|2650268|gb|AAB90870.1| (AE001079) UDP-glucose
4-epimerase (galE-1) [Archaeoglobus fulgidus]
Length = 305
Score = 171 bits (429), Expect = 9e-42
Identities = 104/295 (35%), Positives = 168/295 (56%), Gaps = 10/295 (3%)
Query: 5 LIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
+IVVTGGAGFIGSH+ + L E N++VVIDNL SG E V E + ++AD+ + I + +
Sbjct: 1 MIVVTGGAGFIGSHVVDKLSESNEIVVIDNLSSGNEEFVNEAARLVKADLA-ADDIKDYL 59
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAVYGEP 123
A+ V+H AA V ++P NV+ T +L A+ + G +++F S++ VYGE
Sbjct: 60 KGAEEVWHIAANPDVRIGAENPDEIYRNNVLATYRLLEAMRKAGVSRIVFTSTSTVYGEA 119
Query: 124 TSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYAGVI 183
+P ED+P +PIS YG SK++ E + + + + I R+ NV G R + GVI
Sbjct: 120 KVIPTPEDYPTHPISLYGASKLACEALIESYCHTFDMQAWIYRFANVIGRRSTH---GVI 176
Query: 184 SIFMERALRG-EPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRETTI 242
F+ + R E L I G+G+Q++ ++Y+ D V+A +L + FN+G+ + +
Sbjct: 177 YDFIMKLKRNPEELEILGNGEQNKSYIYISDCVDA-MLFGLRGDERVNIFNIGSEDQIKV 235
Query: 243 IELAMKIIELSSTSSQILFS---KPRPGDIRRSVADIEKIKKLGFKPRYSLEEGL 294
+A + E S + F+ + GD+ + IEK+K+LG+KPRY+ EE +
Sbjct: 236 KRIAEIVCEELGLSPRFRFTGGDRGWKGDVPVMLLSIEKLKRLGWKPRYNSEEAV 290
>pir||A70392 UDP-glucose-4-epimerase - Aquifex aeolicus
>gi|2983546|gb|AAC07120.1| (AE000721)
UDP-glucose-4-epimerase [Aquifex aeolicus]
Length = 327
Score = 170 bits (427), Expect = 2e-41
Identities = 119/322 (36%), Positives = 180/322 (54%), Gaps = 24/322 (7%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAE 62
K ++VTGGAG+IGSH+ +AL E+ +V++ DNL +G V G K ++AD+ D E++
Sbjct: 2 KKVLVTGGAGYIGSHVVKALGEKGYEVLIYDNLSTGNEWAVLYG-KLVKADLADKETLRR 60
Query: 63 IVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAV 119
+ D V H AA I V ESVK+P+ NV+ TIN+L + E G K +F+SSAAV
Sbjct: 61 VFEEFKPDAVMHFAAYIVVPESVKEPLKYYRNNVVNTINLLEVMQEFGVNKFVFSSSAAV 120
Query: 120 YGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQL-YGVPTVILRYFNVYG--PRQS 176
YG P S+P++ED PLNPI+PYG +K + E + V LRYFNV G P
Sbjct: 121 YGIPESIPVKEDAPLNPINPYGETKATVERILRDLKNSGKDFNYVSLRYFNVAGADPEGK 180
Query: 177 SAYAG------VISIFMERALRGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEK 224
+A +I A + L I+G DG RD+++V D+ EA+IL E
Sbjct: 181 IGFAYPNPTHLIIRAVKTAAGEFDRLEIYGTDYPTPDGTCIRDYIHVTDLAEAHILALEY 240
Query: 225 RRAEG--ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK- 281
+ G E N G G +++E+ + +++ +++ + R GD VAD +KIK+
Sbjct: 241 LFSGGKSEVLNCGYGHGYSVLEVVNAVKKVTGVDFKVVEAPRREGDPPALVADNKKIKRV 300
Query: 282 LGFKPRYSLEEGLLET-WKWFK 302
L ++P+Y E +++T W+W K
Sbjct: 301 LNWEPKYDDLEFIIKTAWEWEK 322
>pir||H72588 probable dTDP-glucose 4,6-dehydratase APE1180 - Aeropyrum pernix
(strain K1) >gi|5104852|dbj|BAA80166.1| (AP000061) 330aa
long hypothetical dTDP-glucose 4,6-dehydratase
[Aeropyrum pernix]
Length = 330
Score = 169 bits (425), Expect = 3e-41
Identities = 110/309 (35%), Positives = 168/309 (53%), Gaps = 16/309 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND--VVVIDNL-YSGKPEN---VPEGVKFIEADVRDYES 59
++VTGGAGFIGS + D V+V D L Y+G+ EN V + + F+ D+ D E
Sbjct: 3 VLVTGGAGFIGSSFVRYIVNTTDWEVLVYDKLTYAGRLENLHDVIDRIGFMRGDIADEEQ 62
Query: 60 IAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIF--AS 115
+++ D V + AA+ V+ S+ +P N+IG IL A+ + +++ S
Sbjct: 63 FGRVLTEFEPDVVVNFAAETHVDRSINEPAPFMRTNIIGVFTILEAIRKRIDQIVLLHVS 122
Query: 116 SAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
+ VYG+ T E PLNP SPY SK SG+ K + + YG+ I+R N YGP
Sbjct: 123 TDEVYGDLWNTGKEATESDPLNPSSPYSASKASGDLLIKAYGRTYGLKYRIVRPCNNYGP 182
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
Q +I + R L G+P VI+GDG Q RD++YV+D A +V EK +GE +N
Sbjct: 183 YQH--VEKLIPRTIIRILHGKPPVIYGDGSQIRDWLYVEDTARAIHVVLEK-GVDGEIYN 239
Query: 234 VGTGRETTIIELAMKIIE-LSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEE 292
V G +T+ ++ + I+E + +++ K RPG+ RR +KI+ LG+ P +L+E
Sbjct: 240 VCGGMASTVKDIVVNILESMGKPRDYLVYGKSRPGEDRRYAMKCDKIRNLGWAPHVTLKE 299
Query: 293 GLLETWKWF 301
GL T KW+
Sbjct: 300 GLKITVKWY 308
>gb|AAG18457.1|AF306787_1 (AF306787) AprE [Streptomyces tenebrarius]
Length = 332
Score = 169 bits (423), Expect = 5e-41
Identities = 110/315 (34%), Positives = 162/315 (50%), Gaps = 21/315 (6%)
Query: 6 IVVTGGAGFIGSHIAEALK-------EENDVVVIDNL-YSGKPENVP-------EGVKFI 50
++VTGGAGFIGSH L + +VVV+D L Y+G N+ ++F+
Sbjct: 3 VLVTGGAGFIGSHYVRELLGGAYPAFADAEVVVLDKLTYAGNEANLAPVADAAGSRLRFV 62
Query: 51 EADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNG 109
D+ D E + +++ D V H AA+ V+ S+ NV+GT +L+A L G G
Sbjct: 63 RGDICDAELVRTLMTGVDVVVHFAAESHVDRSILGATEFVMTNVLGTQTLLQAALEAGVG 122
Query: 110 KLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
K + S+ VYG EDHPL P SPY SK S + + F++ +G+P + R N
Sbjct: 123 KFVHVSTDEVYGSIDEGSWPEDHPLEPNSPYSASKASSDLLARAFHRTHGLPVCVTRCSN 182
Query: 170 VYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG 229
YGP Q VI +F+ + G P+ ++GDG RD+++V D LV E R G
Sbjct: 183 NYGPYQFP--EKVIPLFVTNLMDGRPVPLYGDGLNVRDWLHVDDHCRGIQLVVEGGR-PG 239
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKP-RPGDIRRSVADIEKIK-KLGFKPR 287
E +N+G G E T EL +++ + ++ P R G RR DI KI +LG++PR
Sbjct: 240 EVYNIGGGTELTNRELTERLLAVMGADWSMVEQVPDRKGHDRRYSVDITKISTELGYRPR 299
Query: 288 YSLEEGLLETWKWFK 302
EEGL T W++
Sbjct: 300 VPFEEGLARTVAWYR 314
>pir||H69105 dTDP-glucose 4,6-dehydratase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622920|gb|AAB86255.1| (AE000933)
dTDP-glucose 4,6-dehydratase [Methanobacterium
thermoautotrophicum]
Length = 336
Score = 167 bits (419), Expect = 1e-40
Identities = 111/308 (36%), Positives = 165/308 (53%), Gaps = 16/308 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND--VVVIDNL-YSGKPENVPEGVK------FIEADVRD 56
I+VTGGAGFIGS+ + +E+ ++ +D L Y G EN+ GV+ F+ + D
Sbjct: 4 ILVTGGAGFIGSNFIRYMLQEHPYHIINLDALTYCGNLENL-RGVEDEPRYTFVRGSITD 62
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFAS 115
+ + I+ D V + AA+ V+ S++DP N++GT +L A + G + I S
Sbjct: 63 RKLVDGIIKDVDAVINFAAESHVDRSIEDPEIFIRTNILGTQTLLEASRKHGVERFIQIS 122
Query: 116 SAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
+ VYG E+ PL P SPY SK S + + +++ YG+P I R N YGP Q
Sbjct: 123 TDEVYGSAEKGYFTEETPLAPNSPYSASKASADLMVRAYHRTYGLPVNITRCSNNYGPYQ 182
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
+I + + AL +PL ++GDG RD+++V D A LV + R GE +N+G
Sbjct: 183 FP--EKLIPLMITNALENKPLPVYGDGMNVRDWIHVLDHCRAVDLVLHRGRV-GEVYNIG 239
Query: 236 TGRETTIIELAMKII-ELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLEEG 293
E IE+ I+ EL S I F + RPG RR D KI+ +LG+KP YS EEG
Sbjct: 240 GNSERRNIEIVELIVRELGKDESLIRFVEDRPGHDRRYAIDASKIRNELGWKPLYSFEEG 299
Query: 294 LLETWKWF 301
+ ET +W+
Sbjct: 300 IRETIRWY 307
>pir||T48072 dTDP-glucose 4-6-dehydratase homolog D18 - Arabidopsis thaliana
>gi|7362763|emb|CAB83133.1| (AL162651) dTDP-glucose
4-6-dehydratase homolog D18 [Arabidopsis thaliana]
Length = 445
Score = 166 bits (417), Expect = 2e-40
Identities = 109/312 (34%), Positives = 164/312 (51%), Gaps = 15/312 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
+VVTGGAGF+GSH+ + L D V+V+DN ++G+ ENV ++ ++ + I+
Sbjct: 121 VVVTGGAGFVGSHLVDRLMARGDTVIVVDNFFTGRKENVMHHFSNPNFEMIRHDVVEPIL 180
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGEPT 124
D ++H A S +PV T + NV+GT+N+L + + S++ VYG+P
Sbjct: 181 LEVDQIYHLACPASPVHYKFNPVKTIKTNVVGTLNMLGLAKRVGARFLLTSTSEVYGDPL 240
Query: 125 SLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
P E + +NPI S Y K + E +++ V I R FN YGPR
Sbjct: 241 QHPQVETYWGNVNPIGVRSCYDEGKRTAETLTMDYHRGANVEVRIARIFNTYGPRMCIDD 300
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE---TFNVGT 236
V+S F+ +ALR EPL ++GDGKQ+R F +V D+VE + R EGE FN+G
Sbjct: 301 GRVVSNFVAQALRKEPLTVYGDGKQTRSFQFVSDLVEGLM-----RLMEGEHVGPFNLGN 355
Query: 237 GRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLL 295
E T++ELA + E ++ I F D + DI K K+ LG++P+ SL +GL
Sbjct: 356 PGEFTMLELAKVVQETIDPNANIEFRPNTEDDPHKRKPDITKAKELLGWEPKVSLRQGLP 415
Query: 296 ETWKWFKSRTLG 307
K F+ R G
Sbjct: 416 LMVKDFRQRVFG 427
>pir||S58282 dTDP-glucose 4-6-dehydratase homolog D18 - Arabidopsis thaliana
>gi|928932|emb|CAA89205.1| (Z49239) homolog of
dTDP-glucose 4-6-dehydratases [Arabidopsis thaliana]
>gi|1585435|prf||2124427B diamide resistance gene
[Arabidopsis thaliana]
Length = 445
Score = 166 bits (417), Expect = 2e-40
Identities = 109/312 (34%), Positives = 164/312 (51%), Gaps = 15/312 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
+VVTGGAGF+GSH+ + L D V+V+DN ++G+ ENV ++ ++ + I+
Sbjct: 121 VVVTGGAGFVGSHLVDRLMARGDTVIVVDNFFTGRKENVMHHFSNPNFEMIRHDVVEPIL 180
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGEPT 124
D ++H A S +PV T + NV+GT+N+L + + S++ VYG+P
Sbjct: 181 LEVDQIYHLACPASPVHYKFNPVKTIKTNVVGTLNMLGLAKRVGARFLLTSTSEVYGDPL 240
Query: 125 SLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
P E + +NPI S Y K + E +++ V I R FN YGPR
Sbjct: 241 QHPQVETYWGNVNPIGVRSCYDEGKRTAETLTMDYHRGSNVEVRIARIFNTYGPRMCIDD 300
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE---TFNVGT 236
V+S F+ +ALR EPL ++GDGKQ+R F +V D+VE + R EGE FN+G
Sbjct: 301 GRVVSNFVAQALRKEPLTVYGDGKQTRSFQFVSDLVEGLM-----RLMEGEHVGPFNLGN 355
Query: 237 GRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLL 295
E T++ELA + E ++ I F D + DI K K+ LG++P+ SL +GL
Sbjct: 356 PGEFTMLELAKVVQETIDPNANIEFRPNTEDDPHKRKPDITKAKELLGWEPKVSLRQGLP 415
Query: 296 ETWKWFKSRTLG 307
K F+ R G
Sbjct: 416 LMVKDFRQRVFG 427
>gb|AAF25549.1|AF109295_4 (AF109295) GalE [Staphylococcus carnosus]
Length = 329
Score = 166 bits (415), Expect = 4e-40
Identities = 111/324 (34%), Positives = 177/324 (54%), Gaps = 22/324 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++V GGAG+IGSH A+ L E+ DV V+DNL +G + VPE +F E D+RD + +
Sbjct: 3 VLVLGGAGYIGSHAADQLIEQGYDVAVVDNLGTGHRQAVPETARFYEGDIRDKAFLNHVF 62
Query: 65 S--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFASSAAVYG 121
+ + VFH A V ESV+ P+ NV G +L + + ++IF+S+AAVYG
Sbjct: 63 EQENVEGVFHFCAYSLVGESVEKPLEYFNNNVYGMQVLLEVMKAHDVNEIIFSSTAAVYG 122
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY-- 179
EP +PI+ED P P +PYG SK+ E + YGV LRYFNV G ++ +
Sbjct: 123 EPEIIPIQEDAPKAPTNPYGESKLMMEKMMHWCHNAYGVNYAALRYFNVAGAKEDGSIGE 182
Query: 180 -----AGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKRRA 227
+I I ++ AL + + + IFG DG RD+++V D++ A+IL + +
Sbjct: 183 DHNPETHLIPIVLQAALGQRDAITIFGTDYDTEDGSCVRDYLHVTDLIAAHILAYQYLKD 242
Query: 228 EGET--FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGF 284
GE+ FN+G+ + ++IE+ + + + + R GD + VA +K ++ LG+
Sbjct: 243 GGESGAFNLGSSQGYSVIEIVEAARKATGIDIKAEIGERRAGDPSKLVASSDKAQRVLGW 302
Query: 285 KPRYSLEEGLLET-WKWFKSRTLG 307
KP++ ++ET W W +S G
Sbjct: 303 KPKHDDIHEIIETAWNWHQSHPNG 326
>pir||T00419 dTDP-glucose 4-6-dehydratase homolog T30B22.4 - Arabidopsis
thaliana >gi|3738279|gb|AAC63621.1| (AC005309) putative
nucleotide-sugar dehydratase [Arabidopsis thaliana]
Length = 443
Score = 166 bits (415), Expect = 4e-40
Identities = 108/312 (34%), Positives = 165/312 (52%), Gaps = 15/312 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
+VVTGGAGF+GSH+ + L D V+V+DN ++G+ ENV ++ ++ + I+
Sbjct: 123 VVVTGGAGFVGSHLVDRLMARGDNVIVVDNFFTGRKENVMHHFNNPNFEMIRHDVVEPIL 182
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGEPT 124
D ++H A S +PV T + NV+GT+N+L + + S++ VYG+P
Sbjct: 183 LEVDQIYHLACPASPVHYKFNPVKTIKTNVVGTLNMLGLAKRVGARFLLTSTSEVYGDPL 242
Query: 125 SLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
P E + +NPI S Y K + E +++ V I R FN YGPR
Sbjct: 243 QHPQVETYWGNVNPIGVRSCYDEGKRTAETLTMDYHRGANVEVRIARIFNTYGPRMCIDD 302
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE---TFNVGT 236
V+S F+ +ALR EPL ++GDGKQ+R F +V D+VE + R EGE FN+G
Sbjct: 303 GRVVSNFVAQALRKEPLTVYGDGKQTRSFQFVSDLVEGLM-----RLMEGEHVGPFNLGN 357
Query: 237 GRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLL 295
E T++ELA + E +++I F D + DI K K+ LG++P+ +L +GL
Sbjct: 358 PGEFTMLELAKVVQETIDPNAKIEFRPNTEDDPHKRKPDITKAKELLGWEPKVALRQGLP 417
Query: 296 ETWKWFKSRTLG 307
K F+ R G
Sbjct: 418 LMVKDFRQRVFG 429
>sp|Q59083|EXOB_AZOBR UDP-GLUCOSE 4-EPIMERASE (UDP-GALACTOSE 4-EPIMERASE)
(GALACTOWALDENASE) >gi|2120532|pir||I39490 UDPglucose
4-epimerase (EC 5.1.3.2) - Azospirillum brasilense
>gi|396521|emb|CAA80967.1| (Z25478) UDP-glucose
4-epimerase [Azospirillum brasilense]
Length = 348
Score = 165 bits (414), Expect = 5e-40
Identities = 110/313 (35%), Positives = 170/313 (54%), Gaps = 21/313 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++VTGGAG+IGSH+ AL + V ID+L +G+ E +P V +E D+ E + ++
Sbjct: 11 VLVTGGAGYIGSHVLHALTDAGIPAVTIDDLSAGRREAIPAAVPLVEGDIGSAELLDRVM 70
Query: 65 SS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKLIFASSAAVYG 121
D V H A I V ESV P+ N ++ +L A L G K++F+S+AAVYG
Sbjct: 71 RDHRVDAVMHFAGSIVVPESVVKPLDYYRNNTANSLTLLGACLRAGIDKVVFSSTAAVYG 130
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG--PRQSSAY 179
P S+PIRED P PI+PYG SK+ E + +G+ +VILRYFNV G P +
Sbjct: 131 APESVPIREDAPTVPINPYGASKLMTEQMLRDAGAAHGLRSVILRYFNVAGADPAGRTGQ 190
Query: 180 AGVISIFMERAL------RGEPLVIFG------DGKQSRDFVYVKDVVEANIL-VAEKRR 226
A ++ + + R PL IFG DG RD+++V D+ +A++L + RR
Sbjct: 191 ATPVATHLIKVACQALLGRRPPLAIFGTDYDTPDGTCIRDYIHVSDLADAHVLALLHLRR 250
Query: 227 AEGE-TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGF 284
G N G GR ++ E+ + E+S F+ RPGD + VA ++I+ +LG+
Sbjct: 251 GGGSLLMNCGYGRGASVREVVRTLEEVSGEQVPATFADRRPGDPPQLVAGADRIREQLGW 310
Query: 285 KPRYSLEEGLLET 297
P++ +G++ +
Sbjct: 311 VPKHDRLDGIVRS 323
>dbj|BAA84593.1| (AB032523) dTDP-glucose 4,6-dehydratase [Streptomyces avermitilis]
Length = 355
Score = 165 bits (414), Expect = 5e-40
Identities = 112/316 (35%), Positives = 169/316 (53%), Gaps = 20/316 (6%)
Query: 8 VTGGAGFIGSHIAEALKEEN-------DVVVIDNL-YSGKPENVPE-----GVKFIEADV 54
+TGGAGFIGSH L +VVV+D L Y+G+ EN+ + F+ D+
Sbjct: 1 MTGGAGFIGSHFVRRLLTGAYPAFTGAEVVVLDKLTYAGRLENLAPVLGSPSLIFVHGDI 60
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIF 113
D +A+++ +D V H AA+ V+ SV D NV+GT +LRA ++ + ++
Sbjct: 61 CDGPLVADLMDGSDMVVHFAAESHVDRSVADAAEFVRTNVLGTHTLLRAATDAAVDRFVY 120
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S+ VYG S ED PL P SPY SK S + + F++ +G+P +I R N YGP
Sbjct: 121 ISTDEVYGSIDSGSWTEDAPLEPNSPYSASKASSDLLARSFHRTHGLPVIITRCSNNYGP 180
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
Q +I F+ L G + ++GDG+ RD+++V D LVAE+ R GE ++
Sbjct: 181 HQFP--EKLIPRFVTHLLNGTKVPLYGDGENVRDWLHVDDHCRGIALVAERGR-PGEIYH 237
Query: 234 VGTGRETTIIELAMKIIELSSTS-SQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLE 291
+G G E + EL ++++L S + R G RR DI KI +LG+ PR E
Sbjct: 238 IGGGTELSNRELTARLLDLLGVDWSMVEPVTDRKGHDRRYSLDISKISAELGYAPRVPFE 297
Query: 292 EGLLETWKWF-KSRTL 306
EGL +T +W+ ++RTL
Sbjct: 298 EGLAQTVQWYVENRTL 313
>pir||D75486 probable UDP-glucose 4-epimerase - Deinococcus radiodurans (strain
R1) >gi|6458415|gb|AAF10287.1|AE001927_6 (AE001927)
UDP-glucose 4-epimerase, putative [Deinococcus
radiodurans]
Length = 344
Score = 165 bits (414), Expect = 5e-40
Identities = 105/313 (33%), Positives = 160/313 (50%), Gaps = 18/313 (5%)
Query: 5 LIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGK---------PENVPEGVKFIEADVR 55
L+ VTG GFIGSH+ E L V +Y+ + P V E V+ DVR
Sbjct: 18 LVAVTGADGFIGSHLTEDLVRAGYRVRAMAIYNSQGSYGWLDTVPGEVMEHVEVQLGDVR 77
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
D S+ ++ V+H AA I++ S P E N+ GT+N+L A + G G++I
Sbjct: 78 DAGSVRALMRDVQTVYHLAALIAIPYSYVAPRSYVETNITGTLNVLEAARDLGTGRVIHT 137
Query: 115 SSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR 174
S++ VYG S+PI E HPL SPY +K+ + + ++ +G+P V LR FN YGPR
Sbjct: 138 STSEVYGTARSVPIHESHPLQGQSPYSATKIGADKLAESYFLSFGLPVVTLRPFNTYGPR 197
Query: 175 QSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEK-RRAEGETFN 233
QS+ VI + + G + GD + +RDF YV D A V E G T N
Sbjct: 198 QSA--RAVIPTIISQLAAGRTEIKLGDLRPTRDFNYVADTARAFRAVGEAGPEVLGRTLN 255
Query: 234 VGTGRETTIIELAMKIIELSSTSSQILFS----KPRPGDIRRSVADIEKIKKL-GFKPRY 288
G+GRE ++ + I ++ ++ +P ++ R +AD +++ L G++P+
Sbjct: 256 AGSGREISVGDTVKLIAQVMGKDVEVKQEDERLRPEGSEVMRLLADHRELQTLTGWQPQV 315
Query: 289 SLEEGLLETWKWF 301
+LEEGL T +WF
Sbjct: 316 TLEEGLKRTAEWF 328
>sp|Q9KDV3|GALE_BACHD UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|10173723|dbj|BAB04827.1| (AP001510)
UDP-glucose 4-epimerase [Bacillus halodurans]
Length = 334
Score = 164 bits (411), Expect = 1e-39
Identities = 117/327 (35%), Positives = 178/327 (53%), Gaps = 29/327 (8%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
I+VTGGAG+IGSH L E+ + V+V+DNL G + + V F D+RD + + I
Sbjct: 3 ILVTGGAGYIGSHTVLFLLEQGEQVIVLDNLQKGHAGALSD-VTFYHGDIRDDQLLDTIF 61
Query: 65 S--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFASSAAVYG 121
+ S D V H AA V ESVK P+ E NVIGT +L+ + E + K++F+S+AA YG
Sbjct: 62 TTHSIDTVIHFAANSLVGESVKQPIEYYENNVIGTHTLLKKMLEHDVKKIVFSSTAATYG 121
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGE---HYCKVFYQLYGVPTVILRYFNVYGP----- 173
EP +PI+E P P +PYG +K++ E H+C+ + YG+ V LRYFN G
Sbjct: 122 EPVQIPIQESDPTIPTNPYGETKLAIEKMFHWCQ---EAYGLQYVCLRYFNAAGADPNGR 178
Query: 174 --RQSSAYAGVISIFMERAL-RGEPLVIFGDGKQS------RDFVYVKDVVEANILVAEK 224
S + +I I ++ AL + E + IFGD Q+ RD+++V D+ A+ L E
Sbjct: 179 IGEDHSPESHLIPIVLQVALGQRERVAIFGDDYQTEDGSCIRDYIHVMDLANAHYLACEH 238
Query: 225 RRAEGE--TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK- 281
R +G+ +FN+G G+ ++ E+ +++ + R GD +A EK +
Sbjct: 239 LRKDGQSGSFNLGNGKGFSVKEVIEVCRQVTGHPIPAEIAPRRSGDPASLIASSEKAQTI 298
Query: 282 LGFKPRY-SLEEGLLETWKWFKSRTLG 307
LG++P+Y SLE + W W K G
Sbjct: 299 LGWEPKYPSLETMVEHAWNWHKEHPHG 325
>pir||A75008 udp-glucose 4-epimerase (gale-2) PAB1299 - Pyrococcus abyssi
(strain Orsay) >gi|5459017|emb|CAB50503.1| (AJ248288)
UDP-glucose 4-epimerase (galE-2) [Pyrococcus abyssi]
Length = 317
Score = 163 bits (409), Expect = 2e-39
Identities = 107/310 (34%), Positives = 167/310 (53%), Gaps = 21/310 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVP-----EGVKFIEADVRDYES 59
++VTGGAGFIGSH+ + L E+ +V V+D+L +G EN+ E +FI D+RDY+
Sbjct: 3 VLVTGGAGFIGSHLVDRLMEDGYEVRVLDDLSAGSLENLNRWLENENFEFIRGDMRDYKI 62
Query: 60 IAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFASSAA 118
+ E V + VFH AA V S + P E NV+ T N+L+A+ E N K L+F SS+
Sbjct: 63 VKEAVDDVEVVFHLAANPEVRISSQSPELLYETNVLITYNLLQAIRESNVKFLVFTSSST 122
Query: 119 VYGEPTSLPIREDH-PLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS 177
VYG+ LP E + PL PIS YG +K++ E + ++G +I R N+ G R +
Sbjct: 123 VYGDANVLPTPESYGPLEPISVYGGAKLAAEALISGYAHIFGFRALIFRLANIIGKRSNH 182
Query: 178 AYAGVISIFMERALRG-EPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF---N 233
GVI F+ + R L I GDGKQ + +++V D + + + E + + + F N
Sbjct: 183 ---GVIYDFINKLKRNPNELEILGDGKQRKSYLHVSDTINGILHIFEYFKRQNKIFDVYN 239
Query: 234 VGTGRETTIIELAMKIIELSSTSSQILFS------KPRPGDIRRSVADIEKIKKLGFKPR 287
+G T+ E+A + E S + F+ + GD++ + IEK KK G++P+
Sbjct: 240 LGNEDWITVKEIAEIVSEEMGLSPKFKFTGGVDGGRGWKGDVKFMLLSIEKAKKTGWRPK 299
Query: 288 YSLEEGLLET 297
+ E + T
Sbjct: 300 MNSYEAVRRT 309
>pir||T35486 probable nucleotide-sugar dehydratase - Streptomyces coelicolor
>gi|4008544|emb|CAA22513.1| (AL034492) putative
nucleotide-sugar dehydratase [Streptomyces coelicolor
A3(2)]
Length = 330
Score = 162 bits (406), Expect = 4e-39
Identities = 103/307 (33%), Positives = 153/307 (49%), Gaps = 14/307 (4%)
Query: 7 VVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPE-----GVKFIEADVRDYESI 60
+VTGGAGF+GSH+ L + +VV +DNL +G NV + G +F+ D D ++
Sbjct: 20 LVTGGAGFVGSHLCGRLLDAGTEVVCLDNLATGSRANVADLERRRGFRFVRGDATDPAAL 79
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
+ D V H A S + ++ P+ T +V GT N L + + AS++ VY
Sbjct: 80 RGLPGRFDLVLHFACPASPADYLRLPLETLDVGSTGTRNALERAHADGARFLLASTSEVY 139
Query: 121 GEPTSLPIREDH-----PLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
G+P P RE + P+ P S Y SK E Q++G T I+R FN YGPR
Sbjct: 140 GDPLEHPQRETYWGNVNPIGPRSVYDESKRFAEALVTAHRQVHGTDTAIVRIFNTYGPRM 199
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
+ + F+ +AL G PL + GDG Q+R YV D V + +A E N+G
Sbjct: 200 RTGDGRAVPTFIAQALDGMPLTVAGDGGQTRSLCYVDDTVAGVLALAAS--GESGPMNIG 257
Query: 236 TGRETTIIELAMKIIELSSTSSQILF-SKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGL 294
E T++ELA +++ L+ + S+I F +P RR ++LG++P S EGL
Sbjct: 258 GDDEITMLELARRVVGLTGSGSRIRFVERPVDDPCRRRPDTTLARERLGWRPGVSWNEGL 317
Query: 295 LETWKWF 301
T WF
Sbjct: 318 ERTIGWF 324
>pir||G82785 dTDP-glucose 4-6-dehydratase XF0611 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105480|gb|AAF83421.1|AE003906_10
(AE003906) dTDP-glucose 4-6-dehydratase [Xylella
fastidiosa]
Length = 329
Score = 162 bits (405), Expect = 6e-39
Identities = 99/309 (32%), Positives = 168/309 (54%), Gaps = 7/309 (2%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIA 61
N ++VTGGAGF+GSH+ E L +DV+ +DN Y+G ++V + + ++ ++
Sbjct: 20 NNRVLVTGGAGFLGSHLCEKLVASGHDVLCVDNFYTGSKDSVINLIGHPKFELIRHDVTF 79
Query: 62 EIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYG 121
+ D +++ A S DPV T + +V G IN+L +++ AS++ VYG
Sbjct: 80 PLYVEVDRIYNLACPASPVHYQHDPVQTTKTSVHGAINMLGLAKRVKARILQASTSEVYG 139
Query: 122 EPTSLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQS 176
+P P E + +NP+ S Y K E +++ + + + R FN YGPR
Sbjct: 140 DPEIHPQLETYWGRVNPVGIRSCYDEGKRCAETLFFDYWRQHKLEIKVTRIFNTYGPRMH 199
Query: 177 SAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGT 236
V+S F+ +ALRGEP+ I+GDG Q+R F YV D+++ + + E + N+G
Sbjct: 200 PNDGRVVSNFIVQALRGEPITIYGDGTQTRSFCYVDDLIDGMLRMMESPKDFNGPVNIGN 259
Query: 237 GRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLEEGLL 295
E T+++LA +++L + S+I+F D ++ DI K +LG++P+ SLE+GL
Sbjct: 260 PTEFTMLQLAEMVLKLVGSISKIVFQPLPLDDPKQRQPDITLAKSQLGWEPKVSLEDGLR 319
Query: 296 ETWKWFKSR 304
ET +F+ R
Sbjct: 320 ETIAYFRKR 328
>dbj|BAA25656.1| (AB005901) deduced dNDP-hexose 4,6-dehydratase [Streptomyces
kasugaensis]
Length = 329
Score = 161 bits (404), Expect = 8e-39
Identities = 104/311 (33%), Positives = 156/311 (49%), Gaps = 19/311 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVV-----------VIDNLYSGKPENVPEGVKFIEADV 54
++VTG GFIGSH+ E L V V L + V + + D+
Sbjct: 13 VLVTGADGFIGSHLTETLVSRGARVTAVVRRVSAAQVTHRLRNLSAATVDALERVVHVDL 72
Query: 55 RDYESIAEIVS-SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLI 112
++ + AD FH AA V S+ P NV+ T+++L A + L+
Sbjct: 73 AGPSAVDVLGRLEADTWFHLAADAYVPASLDQPADVVRTNVMSTLHVLLAAQQRQPAHLL 132
Query: 113 FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
SS+ VYG I E HPL P +PY SKV+ + ++ YG+P I+R FN YG
Sbjct: 133 VTSSSEVYGSQPDA-ITERHPLEPATPYAASKVACDRLAWSWHHTYGLPLTIVRPFNSYG 191
Query: 173 PRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF 232
PR + +F+ RALRGEP+ I G G+Q+RD +V D V A L + A GET+
Sbjct: 192 PRH---VYDAVPLFLARALRGEPITINGSGEQTRDLTFVADTV-AGFLALAELPATGETY 247
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKI-KKLGFKPRYSLE 291
N+GTG + II++A I+ L+ + S+I+ PR G++ + AD K+ + G++ Y L
Sbjct: 248 NIGTGTDHRIIDVARAIVALTGSQSEIVHGPPRSGEVLKLQADPAKLTEATGWRAEYDLA 307
Query: 292 EGLLETWKWFK 302
GL + W +
Sbjct: 308 RGLADNLVWMR 318
>pir||H69988 NDP-sugar epimerase homolog ytcB - Bacillus subtilis
>gi|2293288|gb|AAC00366.1| (AF008220) YtcB [Bacillus
subtilis] >gi|2635571|emb|CAB15065.1| (Z99119) similar
to NDP-sugar epimerase [Bacillus subtilis]
Length = 316
Score = 160 bits (401), Expect = 2e-38
Identities = 107/304 (35%), Positives = 170/304 (55%), Gaps = 19/304 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEE--NDVVVIDNLYSGKPENV---------PEG-VKFIEAD 53
I+VTG AGFIGSH+ E L ++ ++V+ ID+ P ++ PE FI+ +
Sbjct: 3 ILVTGAAGFIGSHLCEELLKDKKHNVIGIDDFIGPTPFSLKLKNLKNLLPEKRFTFIKEN 62
Query: 54 VRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTIN-ILRALSEGNGK-L 111
+ + +A ++ D +FH AA V S + + I + +L A E + +
Sbjct: 63 LLTAD-LASLLEGVDVIFHLAAIPGVRSSWGNHFHPYAAHNIQALQRLLEACREHSIQTF 121
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+FAS+++VYGE + E+ L+P+SPYGV+K++GE C V+ Q +G+P VILR+F VY
Sbjct: 122 VFASTSSVYGEKQG-KVSENTSLSPLSPYGVTKLTGEKLCHVYKQSFGIPIVILRFFTVY 180
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GPRQ A +++ L+ +PL IFGDG+QSRDF Y+ D V+ V K GET
Sbjct: 181 GPRQRPDMA--FHRLIKQHLQQKPLTIFGDGQQSRDFTYISDCVKGITAVLGKPHLIGET 238
Query: 232 FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSL 290
N+G +++++ I ++S + + FS G+ + ADI K K+ L + P SL
Sbjct: 239 VNIGGAERASVLKVVSLIEDISGRKATLHFSDKIAGEPSNTWADISKAKQLLHYDPATSL 298
Query: 291 EEGL 294
++GL
Sbjct: 299 KDGL 302
>pir||G70415 nucleotide sugar epimerase - Aquifex aeolicus
>gi|2983750|gb|AAC07310.1| (AE000735) nucleotide sugar
epimerase [Aquifex aeolicus]
Length = 321
Score = 160 bits (401), Expect = 2e-38
Identities = 108/313 (34%), Positives = 170/313 (53%), Gaps = 23/313 (7%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPE----------GVKFIEADV 54
I+VTG AG IG ++E L E V+ +DNL S + E KF + ++
Sbjct: 3 ILVTGCAGLIGWKVSEKLLEHGHRVIGVDNLNSYYDPRLKEYRLEQLKKFENFKFYKVNI 62
Query: 55 RDYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKL 111
+ E++ + ++ V +EAA+ V S+++P N +G +N+L + E G KL
Sbjct: 63 ENREALRILFQEFEFDAVINEAARAGVRYSIQNPHIYFTTNTLGNLNLLELMKEFGVKKL 122
Query: 112 IFASSAAVY-GEPTSLPIREDHPLN-PISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
I AS++++Y G+P +P +E+ P+N PISPY SK + E ++ LYG+ VILRYF
Sbjct: 123 ILASTSSLYAGQP--MPFKEELPVNTPISPYAASKKAAEVTAYTYHYLYGIDVVILRYFT 180
Query: 170 VYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG 229
VYG A + F+ + L+G P+ ++GDG Q RDF YV DV EA + +
Sbjct: 181 VYGLAGRPDMA--VFNFIYKTLKGIPIKVYGDGSQKRDFTYVDDVAEATVKALNLKGY-- 236
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRY 288
E NVG + + EL I + + ++ + D+R + ADI K K+ LG++P+
Sbjct: 237 EIINVGNNKPRALKELIELIEKYTGKEVKVEYGDFHKADMRDTWADITKAKRLLGWEPKT 296
Query: 289 SLEEGLLETWKWF 301
SLEEG+ +T +WF
Sbjct: 297 SLEEGVKKTVEWF 309
>pir||A75303 UDP-glucose 4-epimerase - Deinococcus radiodurans (strain R1)
>gi|6460005|gb|AAF11751.1|AE002053_6 (AE002053)
UDP-glucose 4-epimerase [Deinococcus radiodurans]
Length = 394
Score = 160 bits (400), Expect = 2e-38
Identities = 111/325 (34%), Positives = 172/325 (52%), Gaps = 23/325 (7%)
Query: 6 IVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++V GGAG+IGSH L+ ++V V DNL SG E +P V+ I D+ D SI +
Sbjct: 3 LLVVGGAGYIGSHTVRQLRAAGHEVAVFDNLSSGHAEALPGEVELIRGDLLDAASIRAAL 62
Query: 65 SS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG-KLIFASSAAVYG 121
+ D + H AA I V ES++ P NV+GT+N+L+++ E L+F+S+AAVYG
Sbjct: 63 EAQKPDAIIHFAALIEVGESMRAPGRYYRNNVVGTLNLLQSIVETRKVPLVFSSTAAVYG 122
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY-- 179
++PI ED + P S YG +K E F+ +G+P +LRYFNV G
Sbjct: 123 TTDAVPIPEDAAMQPESVYGETKRMSEQMIHAFHVAHGLPYTVLRYFNVCGAAPGGDIGE 182
Query: 180 -----AGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKRRA 227
+I + AL + E ++IFG DG RD+V+V+D+ +A++L E A
Sbjct: 183 AHPNKTHLIELACLTALGQREKMMIFGDDYPTPDGTCIRDYVHVQDLADAHVLAVEALHA 242
Query: 228 ---EGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKI-KKLG 283
+ T+NVG G ++ E+ + + T Q + R GD R VAD +I +LG
Sbjct: 243 GKTDAATYNVGLGHGFSVREVLDAVDAVVGTPLQRELAPRRAGDPPRLVADASRIVDQLG 302
Query: 284 FKPRYSLEEGLLET-WKWFKSRTLG 307
F P+++ +++T W W ++ G
Sbjct: 303 FAPKFTDLRDIVQTAWDWHRTHPQG 327
>pir||T45892 dTDP-glucose 4-6-dehydratase-like protein - Arabidopsis thaliana
>gi|6729503|emb|CAB67659.1| (AL132966) dTDP-glucose
4-6-dehydratase-like protein [Arabidopsis thaliana]
Length = 433
Score = 159 bits (399), Expect = 3e-38
Identities = 103/308 (33%), Positives = 158/308 (50%), Gaps = 11/308 (3%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
IVVTGGAGF+GSH+ + L D V+VIDN ++G+ EN+ ++ ++ + I+
Sbjct: 122 IVVTGGAGFVGSHLVDKLIGRGDEVIVIDNFFTGRKENLVHLFSNPRFELIRHDVVEPIL 181
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGEPT 124
D ++H A S +PV T + NV+GT+N+L + + S++ VYG+P
Sbjct: 182 LEVDQIYHLACPASPVHYKYNPVKTIKTNVMGTLNMLGLAKRVGARFLLTSTSEVYGDPL 241
Query: 125 SLPIREDH-----PLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
P +E + P+ S Y K + E +++ GV I R FN YGPR
Sbjct: 242 EHPQKETYWGNVNPIGERSCYDEGKRTAETLAMDYHRGAGVEVRIARIFNTYGPRMCLDD 301
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRE 239
V+S F+ + +R P+ ++GDGKQ+R F YV D+ LVA FN+G E
Sbjct: 302 GRVVSNFVAQTIRKHPMTVYGDGKQTRSFQYVSDLG----LVALMENDHVGPFNLGNPGE 357
Query: 240 TTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLEEGLLETW 298
T++ELA + E+ S+ I F D + DI K K +L ++P+ SL EGL
Sbjct: 358 FTMLELAEVVKEVIDPSATIEFKPNTADDPHKRKPDISKAKEQLNWEPKISLREGLPRMV 417
Query: 299 KWFKSRTL 306
F++R L
Sbjct: 418 SDFRNRIL 425
>emb|CAC11160.1| (AL445063) UDP-glucose 4-epimerase related protein [Thermoplasma
acidophilum]
Length = 312
Score = 159 bits (399), Expect = 3e-38
Identities = 107/310 (34%), Positives = 164/310 (52%), Gaps = 26/310 (8%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSG-----KPENVPEGVKFIEADVR 55
M K +++TGGAGFIGS++ E L E+NDV VIDNL KP + +FI+
Sbjct: 1 MNGKHVMITGGAGFIGSNMVEMLLEDNDVTVIDNLSIMDDRYIKPFMGKKNFRFIK---- 56
Query: 56 DYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LI 112
E I E V+ DY V H AA V DP NVIGT+N+L + + + K ++
Sbjct: 57 --EDITESVTPGDYDLVVHLAADSDVRNGSVDPTIDLRSNVIGTVNVLEMMRKKDVKDIL 114
Query: 113 FASSAAVYGEPTSLPIREDH-PLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
FASS+ +YGE +P ED+ PL PIS YG SK+S E + + YG+ I R+ N+
Sbjct: 115 FASSSTIYGEAKVMPTPEDYGPLLPISSYGASKLSAEAFISSYSHYYGINAKIFRFANIV 174
Query: 172 GPRQSSAYAGVISIFMERALR-GEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
G + GVI F+ + + + L + GDG Q++ +++V D V + + + R + E
Sbjct: 175 GKNSTH---GVIFDFINKLKKNSKELEVLGDGTQAKSYMHVTDCVGSMFYIYD-RISGTE 230
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPR------PGDIRRSVADIEKIKKLGF 284
FN+G T + +A +IE + K PGD++ + DI+K+K G+
Sbjct: 231 VFNLGNDDVTNVDTIAKYVIEAMGLRDTRIVRKGGYMGRGWPGDVKYARMDIKKLKATGW 290
Query: 285 KPRYSLEEGL 294
K RY+ ++ +
Sbjct: 291 KNRYNSDQAV 300
>dbj|BAB09774.1| (AB016890) dTDP-glucose 4-6-dehydratase [Arabidopsis thaliana]
Length = 342
Score = 159 bits (399), Expect = 3e-38
Identities = 103/300 (34%), Positives = 162/300 (53%), Gaps = 10/300 (3%)
Query: 3 NKLIVVTGGAGFIGSHIAEAL--KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
N I+++GGAGFIGSH+ + L E+N+VVV DN ++G EN+ + + ++ ++
Sbjct: 29 NMRILISGGAGFIGSHLVDKLMENEKNEVVVADNYFTGSKENLKKWIGHPRFELIRHDVT 88
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
++ D ++H A S +PV T + NVIGT+N+L +++ S++ VY
Sbjct: 89 EPLLIEVDRIYHLACPASPIFYKYNPVKTIKTNVIGTLNMLGLAKRVGARILLTSTSEVY 148
Query: 121 GEPTSLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
G+P P E + +NPI S Y K E +++ +G+ I R FN YGPR
Sbjct: 149 GDPLIHPQPESYWGNVNPIGVRSCYDEGKRVAETLMFDYHRQHGIEIRIARIFNTYGPRM 208
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
+ V+S F+ +ALRGE L + G Q+R F YV D+V+ I + E + N+G
Sbjct: 209 NIDDGRVVSNFIAQALRGEALTVQKPGTQTRSFCYVSDMVDGLIRLMEGN--DTGPINIG 266
Query: 236 TGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGL 294
E T++ELA + EL + S +I + P D R+ DI K K+ LG++P+ L EGL
Sbjct: 267 NPGEFTMVELAETVKELINPSIEIKMVENTPDDPRQRKPDISKAKEVLGWEPKVKLREGL 326
>pir||G70330 ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) rfaD [similarity]
- Aquifex aeolicus >gi|2983012|gb|AAC06623.1| (AE000684)
ADP-L-glycero-D-manno-heptose-6-epimerase [Aquifex
aeolicus]
Length = 310
Score = 158 bits (396), Expect = 7e-38
Identities = 117/301 (38%), Positives = 169/301 (55%), Gaps = 20/301 (6%)
Query: 7 VVTGGAGFIGSHIAEALKE---ENDVVVIDNLYSGKPENVPEGVK--FIEADVRDYESIA 61
++TGGAGFIGS++A AL+E E + V+DN SG +N+ G K I D+ D S+
Sbjct: 4 LITGGAGFIGSNLAFALQERYPEAKIYVLDNFSSGHFKNLI-GFKGQVITGDISD-PSLW 61
Query: 62 EIVSSA---DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAA 118
+ V D +FHEAA + +V+D F + N IL E N K+I+ASSA
Sbjct: 62 DYVRKNFHFDVIFHEAA--ITDTTVEDQYFMMKTNADSFRYILDLAVEWNAKVIYASSAG 119
Query: 119 VYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVI-LRYFNVYGPRQS- 176
VYG P+RED L P + YG SK+ +H + + Y ++ LRYFNVYGPR+
Sbjct: 120 VYGNSPP-PMREDKGLEPENIYGFSKLMMDHIAMDYMERYPEMNIVGLRYFNVYGPREDY 178
Query: 177 -SAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
A +I + ++GE +F G+Q RDFVY+KDV++AN+L EK FNVG
Sbjct: 179 KGKTASMIYQLAVKMIKGERPRLFKWGEQRRDFVYIKDVIKANLLALEKN--VSGIFNVG 236
Query: 236 TGRETTIIELAMKIIELSSTSSQI-LFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEG 293
TGR + E+ + + T+ +I F P + + AD+ KI++ LG++P YSLEEG
Sbjct: 237 TGRARSFNEIVSILNKELGTNYEIEYFDCPYDFYQKFTEADLTKIREALGYEPEYSLEEG 296
Query: 294 L 294
+
Sbjct: 297 I 297
>sp|P26503|EXOB_RHIME UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) >gi|95226|pir||S16300
UDPglucose 4-epimerase (EC 5.1.3.2) - Rhizobium meliloti
>gi|581518|emb|CAA41127.1| (X58126) UDP-glucose
4-epimerase [Sinorhizobium meliloti]
Length = 328
Score = 158 bits (396), Expect = 7e-38
Identities = 115/328 (35%), Positives = 170/328 (51%), Gaps = 22/328 (6%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYES 59
M+N I+V GGAG+IGSH L + VV DNL +G E V GV + D+RD +
Sbjct: 1 MQNNNILVVGGAGYIGSHTCLQLAAKGYQPVVYDNLSNGHEEFVKWGV-LEKGDIRDRQR 59
Query: 60 IAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKLIFASS 116
+ E+++ + H AA I V ESVKDP + NVIGT+ +L A L+ G +F+S+
Sbjct: 60 LDEVLARHKPRAILHFAAMIEVGESVKDPAAFYDNNVIGTLTLLSAALAAGIDAFVFSST 119
Query: 117 AAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP--- 173
A YG P S+P+ E H PI+PYG +K E K + G+ +VILRYFN G
Sbjct: 120 CATYGLPDSVPMDESHKQAPINPYGRTKWICEQALKDYGLYKGLRSVILRYFNAAGADFE 179
Query: 174 ----RQSSAYAGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVA 222
I + ++ AL R E +FG DG RD+++V D+ +A++
Sbjct: 180 GRIGEWHEPETHAIPLAIDAALGRREGFKVFGTDYDTRDGTCVRDYIHVLDLADAHVRAV 239
Query: 223 EKRRAEGET--FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK 280
+ GE+ N+GTG TT+ EL I +++ I +++ R GD VA+ +K +
Sbjct: 240 DYLLEGGESVALNLGTGTGTTVKELLDAIEKVAKRPFNIGYAERREGDSTTLVANNDKAR 299
Query: 281 K-LGFKPRYSLEEGLLETWKWFKSRTLG 307
+ LG++P+Y L W W R G
Sbjct: 300 QVLGWEPQYDLAAITESAWNWHSRRNQG 327
>gb|AAC79582.1| (AC005727) putative nucleotide-sugar dehydratase [Arabidopsis
thaliana]
Length = 343
Score = 157 bits (394), Expect = 1e-37
Identities = 102/300 (34%), Positives = 159/300 (53%), Gaps = 10/300 (3%)
Query: 3 NKLIVVTGGAGFIGSHIAEAL--KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
N I+VTGGAGFIGSH+ + L E+N+V+V DN ++G +N+ + + ++ ++
Sbjct: 30 NMRILVTGGAGFIGSHLVDKLMQNEKNEVIVADNYFTGSKDNLKKWIGHPRFELIRHDVT 89
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
+ D ++H A S +PV T + NVIGT+N+L +++ S++ VY
Sbjct: 90 EPLFVEVDQIYHLACPASPIFYKYNPVKTIKTNVIGTLNMLGLAKRVGARILLTSTSEVY 149
Query: 121 GEPTSLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
G+P P E + +NPI S Y K E +++ +G+ I R FN YGPR
Sbjct: 150 GDPLVHPQTESYWGNVNPIGVRSCYDEGKRVAETLMFDYHRQHGIEIRIARIFNTYGPRM 209
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
+ V+S F+ +ALRGE L + G Q+R F YV D+VE + + E + N+G
Sbjct: 210 NIDDGRVVSNFIAQALRGEALTVQKPGTQTRSFCYVSDMVEGLMRLMEGDQT--GPINIG 267
Query: 236 TGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGL 294
E T++ELA + EL +I + P D R+ DI K K+ LG++P+ L EGL
Sbjct: 268 NPGEFTMVELAETVKELIKPDVEIKMVENTPDDPRQRKPDISKAKEVLGWEPKVKLREGL 327
>sp|O84903|GALE_LACCA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|3201657|gb|AAC19329.1| (AF005933)
UDP-galactose 4-epimerase [Lactobacillus casei]
Length = 331
Score = 157 bits (392), Expect = 2e-37
Identities = 108/324 (33%), Positives = 168/324 (51%), Gaps = 22/324 (6%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
I V GGAG+IGSH + + L DVVV+DNL +G + V +F + D+RDY ++++
Sbjct: 3 IAVLGGAGYIGSHTVKQLLAAGEDVVVLDNLITGHRKAVDPRARFYQGDIRDYHFLSQVF 62
Query: 65 SSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAVYG 121
S D + H AA V ES+KDP+ + N G I +L A+++ G K++F+S+AA YG
Sbjct: 63 SQEKIDGIVHFAAFSIVPESMKDPLKYFDNNTGGMITLLEAMNQFGIKKIVFSSTAATYG 122
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY-- 179
EP +PI+E P P +PYG SK++ E YG+ V LRYFNV G +
Sbjct: 123 EPKQVPIKETDPQVPTNPYGESKLAMEKIMHWADVAYGLKFVALRYFNVAGAMPDGSIGE 182
Query: 180 -----AGVISIFMERALRGEP-LVIFG------DGKQSRDFVYVKDVVEANILVAEKRRA 227
++ I ++ A L I+G DG RD+V+V D+ +A+IL + A
Sbjct: 183 DHHPETHIVPIILQVAAGTRTGLQIYGDDYPTKDGTNVRDYVHVVDLADAHILALKYLDA 242
Query: 228 --EGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGF 284
+ FN+G+ + +E+ +++ R GD +A EK + LG+
Sbjct: 243 GNKSSAFNIGSAHGFSNLEILNAARKVTGQEIPATMGPRRAGDPSTLIASSEKARDILGW 302
Query: 285 KPRYSLEEGLLET-WKWFKSRTLG 307
KP Y + ++ET W W ++ G
Sbjct: 303 KPNYDDIDKIIETAWNWHENHPEG 326
>gb|AAF65473.1|AF253311_1 (AF253311) UDP-galactose 4-epimerase [Bradyrhizobium japonicum]
Length = 337
Score = 157 bits (392), Expect = 2e-37
Identities = 107/304 (35%), Positives = 163/304 (53%), Gaps = 21/304 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++VTGGAG+IGSH+ AL + + VVVIDNL +G +PEGV D D + ++
Sbjct: 3 VLVTGGAGYIGSHMVHALVDAGESVVVIDNLSTGFSAFLPEGVPLFIGDAGDENLVEGVI 62
Query: 65 SS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFASSAAVYG 121
+ D + H A + V +S++DP+ N + T ++L A +G + IF+S+AAVYG
Sbjct: 63 AQHGIDSIIHFAGSVVVPDSMRDPLGYYRNNTMTTGSLLNAAVKGGVSRFIFSSTAAVYG 122
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP----RQSS 177
P +P+ E P P+SPYG SK+ E +G+ V+LRYFNV G R
Sbjct: 123 NPDRVPVPEIAPTRPLSPYGSSKLMTEIMLHDVASAHGMSYVVLRYFNVAGADPKGRVGL 182
Query: 178 AYAG---VISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKRRA 227
A G ++ I +E A + + +FG DG RDF++V D+VEA+ RA
Sbjct: 183 ATTGATHLLKIAVEAATGQRAKIDVFGTDYPTQDGSCIRDFIHVSDLVEAHRAALSYLRA 242
Query: 228 EGE--TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGF 284
G+ T N G GR +++E + +S + + ++ RPGDI VAD +I+ L +
Sbjct: 243 GGQSVTLNCGYGRGYSVLETIEAVRRVSMRNFAVAYAARRPGDIMTMVADTTRIRSLLDW 302
Query: 285 KPRY 288
PR+
Sbjct: 303 TPRF 306
>gb|AAG19227.1| (AE005019) UDP-glucose 4-epimerase; GalE1 [Halobacterium sp. NRC-1]
Length = 314
Score = 157 bits (392), Expect = 2e-37
Identities = 105/303 (34%), Positives = 166/303 (54%), Gaps = 16/303 (5%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
+ K IVVTGGAG +GSH A AL +NDV+V D+L G E VP+GV+F D+ D + +
Sbjct: 3 LTGKRIVVTGGAGLVGSHAAGALAGDNDVLVADDLSKGSREAVPDGVEFRRRDMCDPDDV 62
Query: 61 AEIVS-SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGKLIFASSAA 118
A++++ D VFH AA + + + P E N T N+L R + G + F SS+
Sbjct: 63 ADVITPDVDIVFHFAAY--TDTNYEQPRQLFEENGAMTYNVLERMAAVGVDRFAFTSSST 120
Query: 119 VYGEPTSLPIREDH-PLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS 177
VYGE +P ED+ PL PIS YG SK++ E + +G+ + + R+ N+ GPRQ
Sbjct: 121 VYGE-APMPTPEDYAPLEPISVYGASKLADEGLISTYAHAHGITSWVYRFANIVGPRQRG 179
Query: 178 AYAGVISIFMERALRGEP--LVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG-ETFNV 234
V+ F+++ LR +P L I GDG+Q + +++V+D V+A V E + FN+
Sbjct: 180 T---VVPDFIQK-LRADPETLTILGDGRQEKSYLHVEDCVDAMTHVIEHAPSRPLNVFNL 235
Query: 235 GTGRETTIIELAMKIIELSSTSSQILFS---KPRPGDIRRSVADIEKIKKLGFKPRYSLE 291
GT T++ +A + + ++ + GD+ R IEK+ LG++P + +
Sbjct: 236 GTRTTTSVTAIADLVSDELGVDPAYEYTGGDRGWTGDVPRMRLSIEKLAALGWEPTRASD 295
Query: 292 EGL 294
E +
Sbjct: 296 EAV 298
>gb|AAA68211.1| (L37354) thymidine diphosphoglucose 4,6-dehydratase
[Saccharopolyspora erythraea]
Length = 329
Score = 156 bits (391), Expect = 3e-37
Identities = 106/313 (33%), Positives = 161/313 (50%), Gaps = 19/313 (6%)
Query: 6 IVVTGGAGFIGSHIAEALK-------EENDVVVIDNL-YSGKPENV-----PEGVKFIEA 52
++VTGGAGFIGSH L DVVV+D L Y+G EN+ +F+
Sbjct: 3 VLVTGGAGFIGSHYVRQLLGGAYPAFAGADVVVLDKLTYAGNEENLRPVADDPRFRFVRG 62
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-ALSEGNGKL 111
D+ +++ ++E++ D V H AA+ V+ S+ NV+GT +L+ AL+ K
Sbjct: 63 DICEWDVVSEVMREVDVVVHFAAETHVDRSILGASDFVVTNVVGTNTLLQGALAANVSKF 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG EDH L P SPY +K + + +++ +G+P I R N Y
Sbjct: 123 VHVSTDEVYGTIEHGSWPEDHLLEPNSPYSAAKAGSDLIARAYHRTHGLPVCITRCSNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q V+ +F+ + G + ++GDG RD+++V D LVAE RA GE
Sbjct: 183 GPYQFP--EKVLPLFITNLMDGRRVPLYGDGLNVRDWLHVTDHCRGIQLVAESGRA-GEI 239
Query: 232 FNVGTGRETTIIELAMKIIELSSTS-SQILFSKPRPGDIRRSVADIEKI-KKLGFKPRYS 289
+N+G G E T EL +++EL S + R G RR D KI ++LG++P
Sbjct: 240 YNIGGGTELTNKELTERVLELMGQDWSMVQPVTDRKGHDRRYSVDHTKISEELGYEPVVP 299
Query: 290 LEEGLLETWKWFK 302
E GL ET +W++
Sbjct: 300 FERGLAETIEWYR 312
>pir||T45701 dTDP-glucose 4-6-dehydratases-like protein - Arabidopsis thaliana
>gi|6522623|emb|CAB62035.1| (AL133298) dTDP-glucose
4-6-dehydratases-like protein [Arabidopsis thaliana]
Length = 341
Score = 156 bits (391), Expect = 3e-37
Identities = 102/303 (33%), Positives = 163/303 (53%), Gaps = 16/303 (5%)
Query: 3 NKLIVVTGGAGFIGSHIAEAL--KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
N I+++GGAGFIGSH+ + L E+N+V+V DN ++G +N+ + + ++ ++
Sbjct: 28 NMRILISGGAGFIGSHLVDKLMENEKNEVIVADNYFTGSKDNLKKWIGHPRFELIRHDVT 87
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
++ D ++H A S +PV T + NVIGT+N+L +++ S++ VY
Sbjct: 88 EPLLIEVDQIYHLACPASPIFYKYNPVKTIKTNVIGTLNMLGLAKRVGARILLTSTSEVY 147
Query: 121 GEPTSLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
G+P P E + +NPI S Y K E +++ +G+ I R FN YGPR
Sbjct: 148 GDPLIHPQPESYWGNVNPIGVRSCYDEGKRVAETLMFDYHRQHGIEIRIARIFNTYGPRM 207
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE---TF 232
+ V+S F+ +ALRGE L + G Q+R F YV D+V+ + R EG+
Sbjct: 208 NIDDGRVVSNFIAQALRGEALTVQKPGTQTRSFCYVSDMVDGLM-----RLMEGDDTGPI 262
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLE 291
N+G E T++ELA + EL + S +I + P D R+ DI K K+ LG++P+ L
Sbjct: 263 NIGNPGEFTMVELAETVKELINPSIEIKMVENTPDDPRQRKPDITKAKEVLGWEPKVKLR 322
Query: 292 EGL 294
EGL
Sbjct: 323 EGL 325
>emb|CAC14890.1| (AJ295156) d-TDP-glucose dehydratase [Phragmites australis]
Length = 350
Score = 155 bits (389), Expect = 4e-37
Identities = 100/310 (32%), Positives = 165/310 (52%), Gaps = 10/310 (3%)
Query: 3 NKLIVVTGGAGFIGSHIAEAL--KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
N I+VTGGAGFIGSH+ + L E+++V+V DN ++G +N+ + + ++ ++
Sbjct: 34 NLRILVTGGAGFIGSHLVDKLMENEKHEVIVADNFFTGSKDNLKKWIGHPRFELIRHDVT 93
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
++ D ++H A S +PV T + NVIGT+N+L +++ S++ VY
Sbjct: 94 QPLLVEVDQIYHLACPASPIFYKHNPVKTIKTNVIGTLNMLGLAKRVGARILLTSTSEVY 153
Query: 121 GEPTSLPIREDH--PLNPI---SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
G+P P E + +NPI S Y K E +++ +G+ I R FN YGPR
Sbjct: 154 GDPLEHPQTEAYWGNVNPIGVRSCYDEGKRVAETLMFDYHRQHGIEIRIARIFNTYGPRM 213
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
+ V+S F+ +A+RG+PL + G Q+R F YV D+V+ I + N+G
Sbjct: 214 NIDDGRVVSNFIAQAVRGDPLTVQKPGTQTRSFCYVADMVDGLIKLMNGNNT--GPINLG 271
Query: 236 TGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGL 294
E T++ELA K+ EL + + ++ P D R+ DI K K+ LG++P+ L +GL
Sbjct: 272 NPGEFTMLELAEKVKELINPEVTVTMTENTPDDPRQRKPDITKAKEVLGWEPKVVLRDGL 331
Query: 295 LETWKWFKSR 304
+ F+ R
Sbjct: 332 VLMEDDFRER 341
>gb|AAD52168.1|AF144879_7 (AF144879) unknown [Leptospira interrogans]
Length = 332
Score = 155 bits (387), Expect = 8e-37
Identities = 106/321 (33%), Positives = 156/321 (48%), Gaps = 27/321 (8%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGK---------PENVPEGVKFIEADV 54
K I+VTG GFIGSH+ EAL V Y+ ++V + DV
Sbjct: 2 KKILVTGADGFIGSHLTEALVRSGFEVKAFVYYNSFNTWGWLDYCSDDVRGKFEIFTGDV 61
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIF 113
RD + + D V H AA I + S P + N+ GT+N+L+A + N K+I
Sbjct: 62 RDPNGVRTAMKGTDAVLHLAALIGIPYSYHSPDTYIDTNIKGTLNVLQAARDLNLSKVIH 121
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S++ VYG +PI E+HPL SPY SK+ + FY + P +I+R FN YGP
Sbjct: 122 TSTSEVYGTAQFVPITEEHPLKGQSPYSASKIGADQLAYSFYSSFSTPVIIVRPFNTYGP 181
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
RQS+ +I + + L G+ V G +RDF +V D V I + ++ GE N
Sbjct: 182 RQSA--RAIIPTVITQLLSGKTKVQLGSTSPTRDFNFVTDTVNGFISALKSKQGFGEVIN 239
Query: 234 VGTGRETT-------IIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFK 285
+G G E + I + K IE+ S S++I +P ++ R A +K K L ++
Sbjct: 240 IGNGFEISVGDTVKLIANIIGKEIEIVSDSNRI---RPEKSEVERLWASNQKAKDLLNWQ 296
Query: 286 PRYS----LEEGLLETWKWFK 302
P Y+ +GL ET +WFK
Sbjct: 297 PAYNGLQGFRKGLEETIEWFK 317
>gb|AAK41125.1| dTDP-Glucose 4,6-dehydratase (rfbB-1) [Sulfolobus solfataricus]
Length = 317
Score = 154 bits (386), Expect = 1e-36
Identities = 104/302 (34%), Positives = 158/302 (51%), Gaps = 18/302 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNL-YSGKPEN-VPEGVKFIEADVRDYESIAE 62
I+V GGAGFIGS L + +V+D L Y+G+ EN + F++ADVR E + +
Sbjct: 3 IIVVGGAGFIGSAFVRELNKRGIKPIVVDLLTYAGRKENLIGTDYDFVQADVRS-EKMHD 61
Query: 63 IVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
I+ S D V + AA+ V+ S+ P NV+GT+N+L A + N K + S+ VY
Sbjct: 62 IIKEYSPDIVINFAAETHVDRSIYKPQDFVTTNVLGTVNLLEASRKFNFKYVHISTDEVY 121
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYA 180
GE E+ PL P SPY SK S + + K + + YG+ VI+R N YGPRQ
Sbjct: 122 GEECG---DENSPLKPSSPYSASKASADLFVKAYVRTYGISAVIVRPSNNYGPRQFPEK- 177
Query: 181 GVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRET 240
+I + R L G + ++GDGK RD+++V+D V + +GE +N+ G+
Sbjct: 178 -LIPKAIIRTLLGIHIPVYGDGKAERDWIFVEDTARIIFDVVSRAEWKGEVYNIPGGQRY 236
Query: 241 TIIELAMKIIELSSTSSQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYSLEEGLLETWK 299
++E+ + E+S +I F RPG D R + K + FK EGL T++
Sbjct: 237 NVLEILKMLEEVSGKEVKIKFVSDRPGHDRRYCMTTSMKYEVTPFK------EGLRRTYE 290
Query: 300 WF 301
W+
Sbjct: 291 WY 292
>emb|CAB57474.1| (Y18930) dTDP-glucose 4,6-dehydratase (rfbB) [Sulfolobus
solfataricus]
Length = 317
Score = 154 bits (386), Expect = 1e-36
Identities = 104/302 (34%), Positives = 158/302 (51%), Gaps = 18/302 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNL-YSGKPEN-VPEGVKFIEADVRDYESIAE 62
I+V GGAGFIGS L + +V+D L Y+G+ EN + F++ADVR E + +
Sbjct: 3 IIVVGGAGFIGSAFVRELNKRGIKPIVVDLLTYAGRKENLIGTDYDFVQADVRS-EKMHD 61
Query: 63 IVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
I+ S D V + AA+ V+ S+ P NV+GT+N+L A + N K + S+ VY
Sbjct: 62 IIKEYSPDIVINFAAETHVDRSIYKPQDFVTTNVLGTVNLLEASRKFNFKYVHISTDEVY 121
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYA 180
GE E+ PL P SPY SK S + + K + + YG+ VI+R N YGPRQ
Sbjct: 122 GEECG---DENSPLKPSSPYSASKASADLFVKAYVRTYGISAVIVRPSNNYGPRQFPEK- 177
Query: 181 GVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRET 240
+I + R L G + ++GDGK RD+++V+D V + +GE +N+ G+
Sbjct: 178 -LIPKAIIRTLLGIHIPVYGDGKAERDWIFVEDTARIIFDVVSRAEWKGEVYNIPGGQRY 236
Query: 241 TIIELAMKIIELSSTSSQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYSLEEGLLETWK 299
++E+ + E+S +I F RPG D R + K + FK EGL T++
Sbjct: 237 NVLEILKMLEEVSGKEVKIKFVSDRPGHDRRYCMTTSMKYEVTPFK------EGLRRTYE 290
Query: 300 WF 301
W+
Sbjct: 291 WY 292
>gb|AAD11505.1| (U60828) UDP-galactose-4-epimerase [Lactococcus lactis]
Length = 330
Score = 154 bits (385), Expect = 1e-36
Identities = 108/323 (33%), Positives = 167/323 (51%), Gaps = 21/323 (6%)
Query: 6 IVVTGGAGFIGSHIAEAL-KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++V GGAG++GSH + L K DV V+DNL +G E+VP V+F E DVRD+ +A +
Sbjct: 7 VLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANVRFYEGDVRDHAFLASVF 66
Query: 65 SSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAVYG 121
+ + H A V ES++ P+ NV G IL + E G ++F+S+AA +G
Sbjct: 67 EKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFG 126
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY-- 179
P PI E P PI+PYG SK+ E K Q + V LRYFNV G + +
Sbjct: 127 IPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTYVALRYFNVAGAKDDGSIGE 186
Query: 180 -----AGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKRRA 227
+I I ++ AL + E + I+G DG RD++ ++D++EA+I E +A
Sbjct: 187 AHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRDYIDMEDLIEAHIKALEYLKA 246
Query: 228 EGET--FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGF 284
G++ FN+G+ + + +E+ +++ + R GD VAD K + LG+
Sbjct: 247 GGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRAGDPDELVADSTKAGEILGW 306
Query: 285 KPRYSLEEGLLETWKWFKSRTLG 307
K + LE + WKW +S G
Sbjct: 307 KAQNDLEHIITNAWKWHQSHPKG 329
>gb|AAC63021.1| (AF082008) UDP-galactose-4-epimerase [Lactococcus lactis]
Length = 326
Score = 154 bits (385), Expect = 1e-36
Identities = 108/323 (33%), Positives = 167/323 (51%), Gaps = 21/323 (6%)
Query: 6 IVVTGGAGFIGSHIAEAL-KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++V GGAG++GSH + L K DV V+DNL +G E+VP V+F E DVRD+ +A +
Sbjct: 3 VLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANVRFYEGDVRDHAFLASVF 62
Query: 65 SSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAVYG 121
+ + H A V ES++ P+ NV G IL + E G ++F+S+AA +G
Sbjct: 63 EKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFG 122
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY-- 179
P PI E P PI+PYG SK+ E K Q + V LRYFNV G + +
Sbjct: 123 IPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTYVALRYFNVAGAKDDGSIGE 182
Query: 180 -----AGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKRRA 227
+I I ++ AL + E + I+G DG RD++ ++D++EA+I E +A
Sbjct: 183 AHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRDYIDMEDLIEAHIKALEYLKA 242
Query: 228 EGET--FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGF 284
G++ FN+G+ + + +E+ +++ + R GD VAD K + LG+
Sbjct: 243 GGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRAGDPDELVADSTKAGEILGW 302
Query: 285 KPRYSLEEGLLETWKWFKSRTLG 307
K + LE + WKW +S G
Sbjct: 303 KAQNDLEHIITNAWKWHQSHPKG 325
>gb|AAF50474.1| (AE003556) CG7979 gene product [Drosophila melanogaster]
Length = 441
Score = 154 bits (385), Expect = 1e-36
Identities = 100/307 (32%), Positives = 162/307 (52%), Gaps = 9/307 (2%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAE 62
K I++TGGAGF+GSH+ + L + ++V+V+DN ++G+ NV + ++ ++ +
Sbjct: 116 KRILITGGAGFVGSHLVDDLMVQGHEVIVVDNFFTGRKRNVEHWLGHENFELIHHDIVNP 175
Query: 63 IVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGE 122
+ D ++H A+ S + +PV T + N +GTIN+L K++ AS++ VYG+
Sbjct: 176 LFIEIDEIYHLASPASPPHYMYNPVKTIKTNTMGTINVLGLAKRVMAKVLIASTSEVYGD 235
Query: 123 PTSLPIREDH--PLNPISP---YGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS 177
PT P E + +NPI P Y K E + + V + R FN YGPR
Sbjct: 236 PTVHPQPETYWGHVNPIGPRACYDEGKRVSETLSYAYAKQEKVQVRVARIFNTYGPRMHM 295
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
V+S F+ +ALR E + ++G+GKQ+R F YV D+V+ I + + N+G
Sbjct: 296 NDGRVVSNFILQALRNETITVYGNGKQTRSFQYVSDLVDGMIALMASNYT--QPVNLGNP 353
Query: 238 RETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLLE 296
E TI E A I +L S I SK D +R DI + ++ L ++P+ LE GL
Sbjct: 354 VEQTIGEFAEIIKKLVGGPSVIKQSKAMEDDPQRRKPDITRARQLLHWEPKVPLETGLQR 413
Query: 297 TWKWFKS 303
T +F++
Sbjct: 414 TISYFRN 420
>pir||T51252 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [imported] - chickpea
>gi|6469141|emb|CAB61752.1| (AJ275318) dTDP-glucose
4-6-dehydratase [Cicer arietinum]
Length = 346
Score = 153 bits (384), Expect = 2e-36
Identities = 98/301 (32%), Positives = 162/301 (53%), Gaps = 12/301 (3%)
Query: 3 NKLIVVTGGAGFIGSHIAEAL--KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
N I+VTGGAGFIGSH+ + L E+N+V+V DN ++G +N+ + + ++ ++
Sbjct: 32 NMRILVTGGAGFIGSHLVDRLMENEKNEVIVADNYFTGSKDNLKKWIGHPRFELIRHDVT 91
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVY 120
++ D ++H A S +PV T + NVIGT+N+L +++ S++ VY
Sbjct: 92 EPLMIEVDQIYHLACPASPIFYKYNPVKTIKTNVIGTLNMLGLAKRVGARILLTSTSEVY 151
Query: 121 GEPTSLPIREDHPLNPISPYGV------SKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR 174
G+P P E + N ++P GV K E +++ +G+ + R FN YGPR
Sbjct: 152 GDPLEHPQTESYWGN-VNPNGVRNCYDEGKRVAETLMFDYHRQHGIEIRVARIFNTYGPR 210
Query: 175 QSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNV 234
+ V+S F+ +ALRGE L + G Q+R F YV D+V+ L+ ++ N+
Sbjct: 211 MNIDDGRVVSNFIAQALRGESLTVQSPGTQTRSFCYVSDLVDG--LIRLMGGSDTGPINL 268
Query: 235 GTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEG 293
G E T++ELA + EL + + +I + P D R+ DI K K+ LG++P+ L +G
Sbjct: 269 GNPGEFTMLELAETVKELINPNVEIKTVENTPDDPRQRKPDITKAKELLGWEPKVKLRDG 328
Query: 294 L 294
L
Sbjct: 329 L 329
>gb|AAB47842.1| (U61226) RfbB [Leptospira interrogans]
>gi|5814320|gb|AAD52188.1|AF144879_27 (AF144879) unknown
[Leptospira interrogans]
Length = 349
Score = 153 bits (384), Expect = 2e-36
Identities = 112/325 (34%), Positives = 167/325 (50%), Gaps = 30/325 (9%)
Query: 4 KLIVVTGGAGFIGSHIAEAL---KEENDVVVIDNL-YSGKPENVPEGVK-----FIEADV 54
K I+VTGGAGFIGS+ + +E VVV D L Y+G ++ K F++AD+
Sbjct: 2 KKILVTGGAGFIGSNFVNLILNDTKEYQVVVFDKLTYAGNLRSLESWKKDSRFIFVKADI 61
Query: 55 RDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS-EGNG-- 109
+ E ++ I +Y+ H AA+ V+ S+ P + NV+GT +L A + NG
Sbjct: 62 ANKEEVSSIFQEHKFNYIAHFAAESHVDRSISGPEEFIKTNVLGTFYLLDAARLQWNGSY 121
Query: 110 ---KLIFASSAAVYGE-PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVIL 165
K + S+ V+G S E+ P P SPY SK S +H + +Y Y +P V
Sbjct: 122 EGKKFLHVSTDEVFGTLGDSGYFTEETPYAPNSPYSASKASSDHIVRSYYHTYHMPVVTT 181
Query: 166 RYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKR 225
N YGP +I + + L+G+PL ++GDGK RD++YVKD EA + VA +
Sbjct: 182 NCSNNYGPYHFP--EKLIPLMILNCLQGKPLPVYGDGKNIRDWLYVKDHCEA-LRVALFQ 238
Query: 226 RAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPGDIRRSVADIE 277
GET+N+GT E I++ I + + S I + K RPG R D
Sbjct: 239 GLPGETYNIGTRNEKKNIDIVDSICSIMDELHPSGAPHSKLIQYVKDRPGHDFRYAIDPS 298
Query: 278 KI-KKLGFKPRYSLEEGLLETWKWF 301
KI K+LG+KP+++ E L ET +W+
Sbjct: 299 KIEKELGWKPKFAFESALKETVRWY 323
>emb|CAA07655.1| (AJ007747) putative nucleotide sugar epimerase/ dehydratase
[Bordetella bronchiseptica]
Length = 357
Score = 153 bits (382), Expect = 3e-36
Identities = 101/328 (30%), Positives = 172/328 (51%), Gaps = 26/328 (7%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKE--ENDVVVIDNLYSGKPENVPE--GVKFIEADVRD 56
+ N ++V GGAGF+GS++ + L E N V V+DNL S + NVP+ V+F E + D
Sbjct: 10 LANTNVMVVGGAGFVGSNLVKRLLELGVNQVHVVDNLLSAEKINVPDHPAVRFSETSITD 69
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG--KLIFA 114
+A + DYVFH A + S+ DP+ E N + T+ + L K++++
Sbjct: 70 DALLASLQDEYDYVFHLATYHGNQSSIHDPLADHENNTLTTLKLYERLKHFKRLKKVVYS 129
Query: 115 SSAAVYGEPT--SLPIREDHPL----NPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYF 168
++ E T E+ + N SPY +SK+ GE Y +++ + +PTV R+
Sbjct: 130 AAGCSIAEKTFDDAKATEETDIVSLHNNDSPYSMSKIFGEFYSVYYHKQHQLPTVRARFQ 189
Query: 169 NVYGPRQ-----------SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEA 217
NVYGP + ++ + V F+ +AL+G PL + G +RDF++V+DV
Sbjct: 190 NVYGPGEILGAGRWRGTPATVWRNVTPTFIYKALKGMPLPLENGGVATRDFIFVEDVANG 249
Query: 218 NILVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI--RRSVAD 275
I A G +N+ +G+ET+I +LA KI E++ ++++ RP D +R +
Sbjct: 250 LIACAAD-GTPGGVYNIASGKETSIADLATKINEITGNNTELDRLPKRPWDNSGKRFGSP 308
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWFKS 303
+ ++LGF S+++GL +T +W K+
Sbjct: 309 EKARRELGFSADVSIDDGLRKTIEWTKA 336
>gb|AAF73454.1|AF264025_5 (AF264025) putative dTDP-glucose 4, 6-dehydratase; AknR
[Streptomyces galilaeus]
Length = 323
Score = 153 bits (382), Expect = 3e-36
Identities = 103/313 (32%), Positives = 162/313 (50%), Gaps = 17/313 (5%)
Query: 6 IVVTGGAGFIGSHIAEAL-------KEENDVVVIDNL-YSGKPENVPEG---VKFIEADV 54
+++TGGAGFIGSH +L + V V+D L Y+G N+P + F D+
Sbjct: 3 VLITGGAGFIGSHYVRSLLAGTLPGPRPSRVTVVDLLTYAGDTGNLPLADPRLDFRRLDI 62
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKLIF 113
RD +++ +V D V H AA+ V+ S+ +P NV+GT ++L A L G G +
Sbjct: 63 RDLDALLTVVPGHDAVVHFAAETHVDRSLSEPAEFVRTNVLGTQSLLEASLRGGVGTFVH 122
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S+ VYG E+ PL P SPY SK + + +++ +G+ R N YGP
Sbjct: 123 VSTDEVYGSIAQGTWTEEAPLLPNSPYAASKAGSDLVARSYWRTHGLDVRTTRCANNYGP 182
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
RQ +I +F+ L G P+ ++GDG R++++V D A V R GE +N
Sbjct: 183 RQHP--EKLIPLFVTELLAGRPVPLYGDGGNVREWLHVDDHCRAVHAVLTGGR-PGEIYN 239
Query: 234 VGTGRETTIIELAMKIIELSSTS-SQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYSLE 291
+G G T E+ K++ L T S++ R G D+R +V D + ++LG++P SL+
Sbjct: 240 IGGGTHLTNREMTAKLLALCGTDWSRVRQVPDRKGHDLRYAVDDTKIREELGYRPLRSLD 299
Query: 292 EGLLETWKWFKSR 304
+GL E W++ R
Sbjct: 300 DGLREVVDWYRDR 312
>gb|AAD12971.1| (AF078135) RmlB [Leptospira borgpetersenii]
Length = 349
Score = 152 bits (380), Expect = 5e-36
Identities = 111/325 (34%), Positives = 166/325 (50%), Gaps = 30/325 (9%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEND---VVVIDNL-YSGKPENVPEGVK-----FIEADV 54
K I+VTGGAGFIGS+ + EN+ ++V D L Y+G +++ K FI+AD+
Sbjct: 2 KKILVTGGAGFIGSNFVNLILNENEEYQIIVFDKLTYAGNLKSLEYWKKDPRFIFIKADI 61
Query: 55 RDYESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS-EGNG-- 109
+ E++ I + DYV H AA+ V+ S+ P + NV+GT +L A + NG
Sbjct: 62 ANKENVFSIFQEHNFDYVAHFAAESHVDRSILGPEEFIKTNVLGTFYLLDAARLQWNGSY 121
Query: 110 ---KLIFASSAAVYGEPTSLP-IREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVIL 165
K + S+ V+G E+ P P SPY SK +H + +Y Y +P V
Sbjct: 122 EGKKFLHVSTDEVFGTLGDTGYFTEETPYAPNSPYSASKAGSDHIVRSYYHTYHMPVVTT 181
Query: 166 RYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKR 225
N YGP +I + + L+G+PL ++GDGK RD++YVKD EA + +A +
Sbjct: 182 NCSNNYGPYHFP--EKLIPLTILNCLQGKPLPVYGDGKNIRDWLYVKDHCEA-LRLALFQ 238
Query: 226 RAEGETFNVGTGRETTIIELAMKIIELSST--------SSQILFSKPRPGDIRRSVADIE 277
GET+N+GT E I++ I + S I + K RPG R D
Sbjct: 239 GLPGETYNIGTRNEKKNIDIVNSICSIMDEFHPSGVPHSKLIQYVKDRPGHDFRYAIDPS 298
Query: 278 KI-KKLGFKPRYSLEEGLLETWKWF 301
KI K+LG+KP++ E L ET +W+
Sbjct: 299 KIEKELGWKPKFVFESALRETVRWY 323
>gb|AAD44205.1|AF143772_7 (AF143772) GepiA [Mycobacterium avium]
Length = 353
Score = 152 bits (379), Expect = 7e-36
Identities = 108/349 (30%), Positives = 170/349 (47%), Gaps = 51/349 (14%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLY-----SGKPENVPEGVKFIEADVR---D 56
+++TGGAGFIGS ++ L E DV ++D L+ +P + V+ DV D
Sbjct: 5 VLITGGAGFIGSALSRRLVEAGYDVALMDVLHPQVHGGDRPVELAPSVRLFTGDVTHAPD 64
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN---GKLIF 113
++++ + V H AA+ +S+ + VNV+GT +L ALS +L+
Sbjct: 65 FDAVLRLFRPTQIV-HLAAETGTAQSLSEATRHGSVNVVGTTQLLDALSRSGLVPEQLVL 123
Query: 114 ASSAAVYGE-------------PTS---------------------LPIREDHPL-NPIS 138
ASS AVYGE P S LP R D P +
Sbjct: 124 ASSRAVYGEGAWQSGAEVFYPQPRSHAQLVAGRWDPQGPAGEQAVPLPSRADRTEPRPTN 183
Query: 139 PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQS--SAYAGVISIFMERALRGEPL 196
Y +K++ EH + + +LR NVYGP QS ++Y G++++F A +G+ L
Sbjct: 184 VYAATKLAQEHLLAAWTAAHDTNLSVLRLQNVYGPGQSLTNSYTGIVALFARLARQGQAL 243
Query: 197 VIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTS 256
++ DG+ RDFVY+ DVV+A ++ + +VG+GR TTI ELA I +
Sbjct: 244 EVYEDGRIVRDFVYIDDVVDALFAAVQRPASPQRRLDVGSGRATTIQELANTIAAMCEAP 303
Query: 257 SQILFSKPRPGDIRRSVADIE-KIKKLGFKPRYSLEEGLLETWKWFKSR 304
++ K R GD+R + DIE +LG+ P+++LE+GL +W +R
Sbjct: 304 EPVVVGKFRDGDVRAASCDIEPATSQLGWHPKWTLEDGLRALLEWIGNR 352
>gb|AAK40511.1| UDP-glucose 4-epimerase (galE-2) [Sulfolobus solfataricus]
Length = 311
Score = 152 bits (379), Expect = 7e-36
Identities = 101/309 (32%), Positives = 172/309 (54%), Gaps = 22/309 (7%)
Query: 5 LIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEI 63
+ +VTGGAG+IG H+ + L +N +V+VID+L GK N E KF+ D+R +++ E+
Sbjct: 1 MYIVTGGAGYIGGHLVDYLISKNLEVIVIDDLSYGKYRN--EKAKFVMFDLR--QNMGEL 56
Query: 64 VSSAD---YVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG-KLIFASSAAV 119
V + ++H AA V S+ + E +V T+N++ + K+IF SS+ V
Sbjct: 57 VEKLEKNPIIYHLAANPDVRTSMINVEEHFERDVKVTLNVMELARRVDAEKVIFTSSSTV 116
Query: 120 YGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
YGE + +P E L PIS YG+ K+ E+ K + + YG+ ++ R N+ G R S
Sbjct: 117 YGETSKIPTPESEELKPISNYGLFKLLCENIVKYYAEQYGIKSISTRLANITGGRVSH-- 174
Query: 180 AGVISIFMERALRGEP--LVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
GV+ F+++ L+ P L I G+GKQ + ++Y+ D++EA +++ +K + FN+G
Sbjct: 175 -GVVIDFIKK-LKDNPNLLEILGNGKQRKSYLYIDDLIEAFVMLEKKVNRIYDVFNIGNN 232
Query: 238 RETTIIELAMKIIELSSTSSQILFSKPR------PGDIRRSVADIEKI-KKLGFKPRYSL 290
T+ E+A +I+ S +I + P PGD+R + DI KI +++G+ P+ S
Sbjct: 233 DSITVDEIAKIVIDEMKLSPRITYKNPTADGRGWPGDVRLMLLDISKISREVGWSPKMSS 292
Query: 291 EEGLLETWK 299
E + + K
Sbjct: 293 REVIRQAVK 301
>gb|AAD13546.1| (AF080235) NDP-hexose 4,6-dehydratase homolog [Streptomyces
cyanogenus]
Length = 326
Score = 152 bits (379), Expect = 7e-36
Identities = 101/312 (32%), Positives = 164/312 (52%), Gaps = 17/312 (5%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEN-------DVVVIDNL-YSGKPENVPEG---VKFIEA 52
K I++TGGAGFIGSH L + V V+D L Y+G +N+PE + F++
Sbjct: 2 KKILITGGAGFIGSHYVRTLLNDGYEDWKGAHVTVLDKLTYAGNRDNLPEAHPRLTFVQG 61
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKL 111
D+ D+E + E++ D V H AA+ V+ S++ NV GT +L A L+ ++
Sbjct: 62 DICDFELLLELLPGHDAVVHFAAESHVDRSLESAEEFVHTNVTGTQRLLDAVLATRVKRV 121
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG E+ PL P SPY SK + + + +++ +G+ I R N Y
Sbjct: 122 VHVSTDEVYGSIDEGSWTEEWPLAPNSPYSASKAASDLLARSYWRTHGLDLSITRCSNNY 181
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q +I +F+ L GE + ++GDG R++++V D A LV K RA GE
Sbjct: 182 GPYQHP--EKLIPLFVTNLLEGEQVPLYGDGGNIREWLHVDDHCRAIDLVLNKGRA-GEI 238
Query: 232 FNVGTGRETTIIELAMKIIELSSTSSQILFSKP--RPGDIRRSVADIEKIKKLGFKPRYS 289
+N+G G E T + ++I L+ + P + D+R S+ + + ++LG+ PR +
Sbjct: 239 YNIGGGNEQTNRAITERLIALTGQDWSKVRHVPDRKAHDLRYSLDESKIREELGYAPRIT 298
Query: 290 LEEGLLETWKWF 301
E+GL +T W+
Sbjct: 299 FEQGLADTVAWY 310
>gb|AAD12951.1| (AF078135) unknown [Leptospira borgpetersenii]
Length = 332
Score = 151 bits (378), Expect = 9e-36
Identities = 100/318 (31%), Positives = 154/318 (47%), Gaps = 21/318 (6%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNLYSGK------PENVPEGVKFIEADV 54
K I+VTG GFIGSH+ EAL E V N ++ +V + DV
Sbjct: 2 KKILVTGADGFIGSHLTEALVRLGFEVKAFVYYNSFNTWGWLDYCSSDVRGKFEIFTGDV 61
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIF 113
RD + + D V H AA I + S P + N+ GT+N+L+A + N ++I
Sbjct: 62 RDPNGVRTAMKGIDAVLHLAALIGIPYSYHSPDTYVDTNIKGTLNVLQAARDLNLSRVIH 121
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S++ VYG +PI E+HPL SPY SK+ + FY + P +I+R FN YGP
Sbjct: 122 TSTSEVYGTAQFVPITEEHPLKGQSPYSASKIGADQLAYSFYSSFSTPVIIVRPFNTYGP 181
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
RQS+ +I + + L G+ + G +RDF +V D V I + ++ GE N
Sbjct: 182 RQSA--RAIIPTVITQLLSGKTKIQLGSTSPTRDFNFVTDTVNGFISALKSKQGLGEVIN 239
Query: 234 VGTGRETTIIELAMKIIELSSTSSQILFS----KPRPGDIRRSVADIEKIKKL-GFKPRY 288
+G G E ++ + I + +I+ +P ++ R + +K K L G++P Y
Sbjct: 240 IGNGFEISVGDTVKLIASILDKEVEIVSDVNRIRPEKSEVERLWSSNQKAKDLFGWQPAY 299
Query: 289 S----LEEGLLETWKWFK 302
S + GL ET +WF+
Sbjct: 300 SGLEGFKRGLTETIEWFR 317
>emb|CAB44218.1| (AJ011653) UDP-galactose 4-epimerase [Lactococcus lactis]
Length = 326
Score = 151 bits (378), Expect = 9e-36
Identities = 106/323 (32%), Positives = 167/323 (50%), Gaps = 21/323 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++V GGAG++GSH + L DV V+DNL +G E V E V+F E DVRD+ +A +
Sbjct: 3 VLVLGGAGYVGSHAVDMLVNRGYDVAVVDNLVTGHREAVSEKVRFYEGDVRDHAFLASVF 62
Query: 65 SSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAVYG 121
+ + H A V ES++ P+ NV G IL + E G ++F+S+AA +G
Sbjct: 63 EKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFG 122
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY-- 179
P PI E P PI+PYG SK+ E K Q + V LRYFNV G + +
Sbjct: 123 IPEESPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTYVALRYFNVAGAKDDGSIGE 182
Query: 180 -----AGVISIFMERAL-RGEPLVIFGDGKQS------RDFVYVKDVVEANILVAEKRRA 227
+I I ++ AL + E + I+GD Q+ RD++ ++D++EA+I E ++
Sbjct: 183 AHKNETHLIPIILQTALGQREFITIYGDDYQTPDGTCIRDYIDMEDLIEAHIKALEYLKS 242
Query: 228 EGET--FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGF 284
G++ FN+G+ + + +E+ +++ + RPGD VAD K + LG+
Sbjct: 243 GGKSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRPGDPDELVADSTKAGEILGW 302
Query: 285 KPRYSLEEGLLETWKWFKSRTLG 307
K + LE + W+W +S G
Sbjct: 303 KVKNDLEHIITNAWEWHQSHPKG 325
>pir||S75089 UDP-glucose 4-epimerase - Synechocystis sp. (strain PCC 6803)
>gi|1653034|dbj|BAA17951.1| (D90910) UDP-glucose
4-epimerase [Synechocystis sp.]
Length = 338
Score = 150 bits (376), Expect = 1e-35
Identities = 108/322 (33%), Positives = 167/322 (51%), Gaps = 23/322 (7%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENV-PEGVKFIEADVRDYESIAEI 63
I+VTGGAG+IGSH AL++ DV++ DNL G E V P GV+ + D + + ++
Sbjct: 7 ILVTGGAGYIGSHGVLALQQAGFDVLIYDNLSYGHKELVQPLGVELVVGHTGDRQKLDQL 66
Query: 64 VSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKLIFASSAAVY 120
++ + V H AA I+V ESV+ P + NV+GT+ +L A L+ G K +F+S+ AVY
Sbjct: 67 FATRNIAAVMHFAAFIAVGESVQKPDIYYQNNVVGTLTLLEAMLAAGIKKFVFSSTCAVY 126
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP------- 173
G P +P+ E HP++P+SPY SK E F Q YG +VI RYFN G
Sbjct: 127 GMPKEIPMTESHPIDPLSPYAASKRMVEQILADFDQAYGFKSVIFRYFNASGADPQGRLG 186
Query: 174 RQSSAYAGVISIFMERALRGEP-LVIFG------DGKQSRDFVYVKDVVEANILVAEKRR 226
+ +I + + AL+ P L +FG DG RD+++V D+ A++L +
Sbjct: 187 EDHNPETHLIPLALLTALKQRPQLSVFGTDYDTLDGTALRDYIHVCDLAIAHVLGLQYLL 246
Query: 227 AEGET--FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LG 283
GE+ FN+G G ++ ++ ++ RPGD V K ++ LG
Sbjct: 247 EGGESNIFNLGNGNGFSVRQVIEVAKAVTGLDIPYQLCPRRPGDAPILVGSSAKAREILG 306
Query: 284 FKPRY-SLEEGLLETWKWFKSR 304
+ P+Y L + W+W + R
Sbjct: 307 WNPQYPDLHTIIDHAWQWHQRR 328
>emb|CAB61555.1| (AL133171) putative dehydratase [Streptomyces coelicolor A3(2)]
Length = 324
Score = 150 bits (376), Expect = 1e-35
Identities = 102/309 (33%), Positives = 160/309 (51%), Gaps = 15/309 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND-----VVVIDNL-YSGKPENVPEG---VKFIEADVRD 56
I+VTG AGFIGS L + V V+D L Y+G N+ G ++F+ D+RD
Sbjct: 3 ILVTGAAGFIGSRYVRGLLASDAPGAPRVTVLDALTYAGSTANLELGHPRLEFVHGDIRD 62
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGKLIFAS 115
+ + + AD V H AA+ V+ S+ NV+GT N+L AL G G + S
Sbjct: 63 AALVDRLTAGADQVVHFAAESHVDRSIHAASDFVLTNVVGTQNLLDAALRHGVGPFVHVS 122
Query: 116 SAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
+ VYG + E+HPL P SPY SK SG+ +++ +G+ + R N YGP Q
Sbjct: 123 TDEVYGSVDAGSATEEHPLRPSSPYSASKASGDLLALSYHRTHGLDVRVTRCSNNYGPHQ 182
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVG 235
++ +F+ R L G + ++GDG+ RD+++V D LV + RA GE +N+G
Sbjct: 183 FP--EKLVPLFVTRLLDGHRVPLYGDGRNVRDWLHVDDHCRGVDLVRTRGRA-GEVYNIG 239
Query: 236 TGRETTIIELAMKIIELSSTS-SQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYSLEEG 293
G E + +L +++ +I+ + R G D+R SV + ++LG++P L G
Sbjct: 240 GGTELSNRDLTGLLLDACGAGPDRIVHVEDRKGHDLRYSVDWSKAREELGYRPHRDLATG 299
Query: 294 LLETWKWFK 302
L ET W++
Sbjct: 300 LAETVAWYR 308
>gb|AAF82605.1| (AF144042) dTDP-glucose 4,6-dehydratase [Streptomyces rimosus
subsp. paromomycinus]
Length = 317
Score = 150 bits (376), Expect = 1e-35
Identities = 104/312 (33%), Positives = 164/312 (52%), Gaps = 22/312 (7%)
Query: 7 VVTGGAGFIGSHIAEALKEEND----VVVIDNL-YSGKPENVPE-----GVKFIEADVRD 56
+VTGGAGFIGSH +L + V V+D L Y+G N+ ++F++ D+ D
Sbjct: 4 LVTGGAGFIGSHFVRSLLADGTGQEAVTVLDALTYAGNLANLRSVQGDPRLRFVQGDILD 63
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG-KLIFAS 115
+AE+V+ D V + AA+ V+ S+ + NV+GT +L A + G ++ S
Sbjct: 64 SARVAELVAGHDAVVNLAAESHVDRSIANGAKFSSTNVLGTQTLLEAAVQAGGVTVVHVS 123
Query: 116 SAAVYGEPTSLPI---REDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
+ VYG S+PI E+ PL P SPY +K + +++ +G+ I R N YG
Sbjct: 124 TDEVYG---SIPIGSWTEEEPLAPNSPYAAAKAGSDLLALAYHRTHGLDVRITRCSNNYG 180
Query: 173 PRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF 232
P Q +I +F+ R L+G + ++GDG Q RD+++V D A LV E RA GE +
Sbjct: 181 PYQFP--EKIIPLFITRLLQGRKVPLYGDGSQIRDWLHVVDHCRAIRLVLEGGRA-GEIY 237
Query: 233 NVGTGRETTIIELAMKIIELSSTS-SQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSL 290
NVG G E T L ++++ + R G +R D KI+ +LG++PR++
Sbjct: 238 NVGGGTELTNKHLTDRLLDACGADWDSVEHVADRKGHDQRYSVDWSKIRDELGYEPRHTF 297
Query: 291 EEGLLETWKWFK 302
+EGL T W++
Sbjct: 298 DEGLASTVSWYR 309
>pir||H71145 probable UDP-glucose 4-epimerase - Pyrococcus horikoshii
>gi|3256770|dbj|BAA29453.1| (AP000002) 318aa long
hypothetical UDP-glucose 4-epimerase [Pyrococcus
horikoshii]
Length = 318
Score = 150 bits (375), Expect = 2e-35
Identities = 101/311 (32%), Positives = 165/311 (52%), Gaps = 23/311 (7%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVP-----EGVKFIEADVRDYES 59
++VTGGAGFIGSH+ + L EE V V+D+L +G +N+ E +FI+ D+RD E
Sbjct: 3 VLVTGGAGFIGSHLVDRLMEEGYKVRVLDDLSAGSLKNIEGWLGNENFEFIKGDMRDVEI 62
Query: 60 IAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFASSAA 118
+++ V D VFH AA V + P E NV+ T N+L A+ K L+F SS+
Sbjct: 63 VSKAVKDVDAVFHLAANPEVRIGSQSPELLYETNVLITYNLLNAVRNSGVKYLVFTSSST 122
Query: 119 VYGEPTSLPIREDH-PLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS 177
VYG+ +P ED+ PL PIS YG +K++ E + + +I+R N+ G R +
Sbjct: 123 VYGDAKVIPTPEDYAPLEPISVYGAAKLAAEALISGYAHTFDFRALIIRLANIIGKRSNH 182
Query: 178 AYAGVISIFMERALRGEP--LVIFGDGKQSRDFVYVKDVVEANILVAE---KRRAEGETF 232
GVI F+ + L+ P L I GDG Q + ++++ D ++ + + E + +
Sbjct: 183 ---GVIYDFINK-LKANPNELEILGDGTQRKSYLHISDTIDGIMKLFEHFLNGEERVDFY 238
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFS------KPRPGDIRRSVADIEKIKKLGFKP 286
N+G T+ E+A + E + + + F+ + GD++ + IEK K+ G+KP
Sbjct: 239 NLGNEDWITVKEIAEIVSEEMNLNPRFKFTGGVDGGRGWKGDVKLMLLSIEKAKRTGWKP 298
Query: 287 RYSLEEGLLET 297
R + E + +T
Sbjct: 299 RMNSYEAVRKT 309
>gb|AAK41973.1| dTDP-Glucose 4,6-dehydratase (rfbB-3) [Sulfolobus solfataricus]
Length = 312
Score = 149 bits (373), Expect = 3e-35
Identities = 100/299 (33%), Positives = 160/299 (53%), Gaps = 14/299 (4%)
Query: 6 IVVTGGAGFIGS-HIAEALKEENDVVVIDNL-YSGKPEN-VPEGVKFIEADVRDYESIAE 62
+++ GGAGFIGS + E K +V+D L Y+G+ EN + +FI ADVR E I +
Sbjct: 1 MIIIGGAGFIGSAFVREVNKRGIKPIVVDLLTYAGRKENLIGTEHEFIRADVRS-EEIHD 59
Query: 63 IVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGE 122
IV ++D V + AA+ V+ S+ P NV+G +N+L A + + K + S+ VYGE
Sbjct: 60 IVKNSDIVVNFAAETHVDRSIYRPQDFVTTNVLGVVNLLEAARKYDFKYVHISTDEVYGE 119
Query: 123 PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYAGV 182
+ ED PL P SPY SK S + + K + + YG+ +I+R N YGPRQ +
Sbjct: 120 ECA---DEDSPLQPSSPYSASKASADLFVKAYVRTYGIKAIIVRPSNNYGPRQFP--EKL 174
Query: 183 ISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRETTI 242
I + R + I+GDG+ RD++YV+D V + E+ GE +N+ G+ ++
Sbjct: 175 IPKVIIRTFLNMHVPIYGDGRAERDWIYVEDTVRIIYDIMERSEWRGEVYNIPGGQRYSV 234
Query: 243 IELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEEGLLETWKWF 301
+++ I E+ ++ F RPG +R KL ++ L+EGL +T +W+
Sbjct: 235 LDVIKIIGEIMGKEVKVKFVDDRPGHDKRYC----MTTKLKYEVT-PLKEGLRKTVEWY 288
>pir||B75098 dtdp-glucose 4,6-dehydratase (rfbb) PAB0785 - Pyrococcus abyssi
(strain Orsay) >gi|5458599|emb|CAB50087.1| (AJ248286)
dTDP-glucose 4,6-dehydratase (rfbB) [Pyrococcus abyssi]
Length = 333
Score = 149 bits (373), Expect = 3e-35
Identities = 106/312 (33%), Positives = 165/312 (51%), Gaps = 22/312 (7%)
Query: 6 IVVTGGAGFIGSH-IAEALKEEND--VVVIDNL-YSGKPENVPE-----GVKFIEADVRD 56
I+VTGG GFIGS+ I L++ ND V+ +D L Y P N+ + F++ DV D
Sbjct: 3 ILVTGGMGFIGSNFIRYILEKHNDWEVINLDKLTYGSNPANLKDIQDDPRYTFVKGDVAD 62
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG--KLIFA 114
+E + E++ D + H AA+ V+ S+ P NVIGT +L A+ + N +L+
Sbjct: 63 FELVRELIKKVDAIVHFAAESHVDRSISSPDNFLHSNVIGTYTLLEAIRKENPGVRLVHI 122
Query: 115 SSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR 174
S+ VYG+ E+ L P SPY +K + + + + YG+ I R N YGP
Sbjct: 123 STDEVYGDILKGSFTEEDRLMPSSPYSATKAASDMLVLGWARTYGLNASITRCTNNYGPY 182
Query: 175 QSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKD---VVEANILVAEKRRAEGET 231
Q +I + RA G + I+G GK RD++YV+D +EA +L E R E
Sbjct: 183 QFP--EKLIPKTIIRAKMGLKVPIYGTGKNVRDWLYVEDHVRAIEAVLLKGEAR----EI 236
Query: 232 FNVGTGRETTIIELAMKIIE-LSSTSSQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYS 289
+N+ G E T +E+ I+ + S I F + RPG DIR S+ + I++L ++P+Y
Sbjct: 237 YNISAGEERTNLEVVRTILRIMDKDESLIEFVEDRPGHDIRYSLDSWKIIRELKWRPKYR 296
Query: 290 LEEGLLETWKWF 301
EEG+ +T +W+
Sbjct: 297 FEEGIKKTVEWY 308
>dbj|BAB06023.1| (AP001515) nucleotide sugar epimerase (capsular polysaccharide
biosynthesis) [Bacillus halodurans]
Length = 315
Score = 149 bits (373), Expect = 3e-35
Identities = 103/305 (33%), Positives = 160/305 (51%), Gaps = 22/305 (7%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVID-----NLYSGKPENVPEGVK-----FIEAD 53
I+VTG AGFIGSH+ E L E+ VV +D +L K NV +K ++ D
Sbjct: 3 ILVTGAAGFIGSHLCEQLLMNEKVSVVGVDGHIDSSLCKVKERNVRNLLKHPRFTLLKQD 62
Query: 54 VRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEV--NVIGTINILRALSEGN-GK 110
+ + + +V D ++H + V S F + V N++ T +L A + K
Sbjct: 63 LLTID-LEPLVDQVDVIYHLSGIPGVRSSWGTD-FKKYVTHNIVATQQLLEACRRHSLEK 120
Query: 111 LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
I+ S+++VYG+ + E P+SPYGVSK++GEH C V+Y+ + +PTVILRYF V
Sbjct: 121 FIYISTSSVYGQKNG-KVGEKASPTPLSPYGVSKLTGEHLCNVYYRNFSIPTVILRYFTV 179
Query: 171 YGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
YGPRQ A F++ + +P+ IFGDG QSRDF Y+ D + A V GE
Sbjct: 180 YGPRQRQDMA--FHRFIKAIIDNQPIPIFGDGNQSRDFTYIDDCIAATCAVLH-ADVIGE 236
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYS 289
T N+G T++++ + + +++ F + G+ + ADI K +K L + P
Sbjct: 237 TINIGGKERATVLQIISMLESIFQKDAKLQFLEKPFGEPMSTWADISKAEKLLRYSPNVP 296
Query: 290 LEEGL 294
L +G+
Sbjct: 297 LLQGI 301
>sp|Q59745|EXOB_RHILT UDP-GLUCOSE 4-EPIMERASE (UDP-GALACTOSE 4-EPIMERASE)
(GALACTOWALDENASE) >gi|1360122|emb|CAA65359.1| (X96507)
UDP-glucose 4-epimerase [Rhizobium leguminosarum]
Length = 327
Score = 148 bits (371), Expect = 6e-35
Identities = 112/323 (34%), Positives = 165/323 (50%), Gaps = 26/323 (8%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYES 59
M + ++V GGAG+IGSH L + VV DN +G E V G E D+RD
Sbjct: 1 MAGETVLVVGGAGYIGSHTCLDLANKGYRPVVFDNFSNGHREFVRWGPAE-EGDIRDRAR 59
Query: 60 IAEIVSSAD--YVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGNGKLIFASS 116
+ E+++ + H AA I V ESVKDPV E NVIGT+ +L A + G +F+S+
Sbjct: 60 LDEVLAKHKPAAILHFAALIEVGESVKDPVSFYENNVIGTLTLLSAAQAAGINAFVFSST 119
Query: 117 AAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP--- 173
A YG P S+P+ E H PI+PYG +K E + Q + +V+LRYFN G
Sbjct: 120 CATYGLPQSVPLDETHRQVPINPYGRTKYIVEQALADYDQYGSLRSVVLRYFNAAGADFE 179
Query: 174 ------RQSSAYAGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANIL 220
Q +A I + ++ AL R + +FG DG RD+++V D+ +A++
Sbjct: 180 GRIGEWHQPETHA--IPLAIDAALGRRQGFKVFGSDYETRDGTCVRDYIHVLDLADAHVR 237
Query: 221 VAEKRRAEGET--FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEK 278
E G++ N+GTG TT+ EL I E+S+ + + R GD VA+ +K
Sbjct: 238 AVEYLLKGGDSVALNLGTGTGTTVKELLGAIEEVSNRPFPVEYIGRREGDSHTLVANNDK 297
Query: 279 IKK-LGFKPRYSLEEGLLETWKW 300
+ LG+ P+Y L E + W W
Sbjct: 298 ARDVLGWVPQYDLSEIIRSAWDW 320
>pir||I55054 dTDP-D-glucose 4,6-dehydratase - Escherichia coli
Length = 361
Score = 148 bits (371), Expect = 6e-35
Identities = 112/339 (33%), Positives = 169/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVIDNL-YSGKPENVP-----EGVKFIEADVRDY 57
I+VTGGAGFIGS + + ++ VV +D L Y+G E++ E F AD+ D
Sbjct: 3 ILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNRESLADVSDSERYVFEHADICDA 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL----------S 105
++A I + D V H AA+ V+ S+ P E N++GT +L A
Sbjct: 63 PAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSALDSDK 122
Query: 106 EGNGKLIFASSAAVYGE---PTSLPIREDHPL-------NPISPYGVSKVSGEHYCKVFY 155
E + + S+ VYG+ P + E+ PL P SPY SK S +H + +
Sbjct: 123 ENSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTAYAPSSPYSASKASSDHLVRAWK 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A V + +A GET+N+G E I++ + I +L S QI + RPG
Sbjct: 241 RALYTVVTEVKA-GETYNIGGHNEKKNIDVVLTICDLLDEIVPKEKSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D EKI + LG+KP+ + E G+ +T +W+ S T
Sbjct: 300 HDRRYAIDAEKIGRALGWKPQETFESGIRKTVEWYLSNT 338
>sp|Q58455|YA55_METJA HYPOTHETICAL PROTEIN MJ1055 >gi|2127791|pir||F64431 capsular
polysaccharide biosynthesis protein I homolog -
Methanococcus jannaschii >gi|1591707|gb|AAB99057.1|
(U67548) capsular polysaccharide biosynthesis protein I
[Methanococcus jannaschii]
Length = 326
Score = 148 bits (370), Expect = 7e-35
Identities = 106/321 (33%), Positives = 168/321 (52%), Gaps = 25/321 (7%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALK---EENDVVVIDNLYS-------GKPENVP---EGV 47
M+ K I+VTG AGFIG H+++ L E+ V+ IDNL + K + E
Sbjct: 1 MKYKNILVTGSAGFIGFHLSKYLMDNYEDLKVIGIDNLNNYYNPVLKEKRNEILKNYENY 60
Query: 48 KFIEADVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS 105
FI+ D D++ + E + D + H AQ V S+++P + N +GT+NI
Sbjct: 61 TFIKLDFSDWDDLVENLKDKEIDLIVHLGAQAGVRYSLQNPWAYIKSNEMGTLNIFEFAR 120
Query: 106 EGN-GKLIFASSAAVYGEPTSLPIREDHPLN-PISPYGVSKVSGEHYCKVFYQLYGVPTV 163
+ K+++ASS++VYG +P ED ++ PIS Y +K S E V++ LYG+ +
Sbjct: 121 RFDIEKVVYASSSSVYGGNRKIPFSEDDRVDKPISLYASTKRSNELMAHVYHHLYGIKMI 180
Query: 164 ILRYFNVYGP--RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILV 221
LR+F VYG R AY F + L G+ + ++ G RDF Y+ DVV+ IL
Sbjct: 181 GLRFFTVYGEYGRPDMAYFK----FAKNILLGKEIEVYNYGNMERDFTYISDVVD-GILR 235
Query: 222 AEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK 281
A K+ + E FN+G + ++ I + + ++ F + GD+ R+ AD+ K +K
Sbjct: 236 AIKKDFDYEIFNLGNSKPVKLMYFIELIEKYLNKKAKKKFLPMQDGDVLRTYADLSKSEK 295
Query: 282 -LGFKPRYSLEEGLLETWKWF 301
LG+KP+ ++EEGL WF
Sbjct: 296 LLGYKPKVTIEEGLKRFCNWF 316
>emb|CAA77209.1| (Y18523) dTDP-glucose 4,6-dehydratase [Actinoplanes sp. 50/110]
Length = 341
Score = 148 bits (370), Expect = 7e-35
Identities = 106/315 (33%), Positives = 157/315 (49%), Gaps = 20/315 (6%)
Query: 6 IVVTGGAGFIGSHIAEAL--------KEENDVVVIDNL-YSGKPENVPEG-----VKFIE 51
I+VTGGAGFIGSH +L + V V+D L Y G N+ E F+
Sbjct: 3 ILVTGGAGFIGSHFVTSLISGDIATPQPVTQVTVVDKLGYGGNLRNLAEASADPRFSFVR 62
Query: 52 ADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGK 110
D+ D I +++ D V H AA+ V+ SV N++GT +L AL G+
Sbjct: 63 GDICDEGLIEGLMARHDTVAHFAAETHVDRSVVASGPFVASNLVGTQVLLDAALRHHIGR 122
Query: 111 LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
+ S+ VYG + E HPL P SPY SK + ++Q +G+ V+ R N
Sbjct: 123 FLHVSTDEVYGSIDTGSWAEGHPLAPNSPYAASKAGSDLLALAYHQTHGMDVVVTRCSNN 182
Query: 171 YGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
YGPRQ +I +F+ R L G + ++GDG+ RD+++V D L RA GE
Sbjct: 183 YGPRQFP--EKMIPLFVTRLLDGLDVPVYGDGRNIRDWLHVSDHCRGLALALGAGRA-GE 239
Query: 231 TFNVGTGRETTIIELAMKIIE-LSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRY 288
+++G G E T +EL ++E + S+I F R G RR D KI +LG++PR
Sbjct: 240 VYHIGGGWEATNLELTEILLEACGARRSRISFVTDRKGHDRRYSLDYSKIAGELGYRPRV 299
Query: 289 SLEEGLLETWKWFKS 303
+G+ ET W+++
Sbjct: 300 DFTDGIAETVAWYRA 314
>pir||S49054 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [similarity] -
Streptomyces fradiae (strain T59235)
>gi|473600|gb|AAA21344.1| (U08223) dTDP-glucose
dehydratase [Streptomyces fradiae]
Length = 333
Score = 148 bits (369), Expect = 1e-34
Identities = 102/313 (32%), Positives = 155/313 (48%), Gaps = 19/313 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKE-------ENDVVVIDNL-YSGKPENVPE-----GVKFIEA 52
++VTGGAGFIGSH L VV+D L Y+G P N+ ++F+
Sbjct: 3 VLVTGGAGFIGSHFTGQLLTGAYPDLGATRTVVLDKLTYAGNPANLEHVAGHPDLEFVRG 62
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKL 111
D+ D+ ++ V H AA+ V+ S++ NV GT +L+A + G G+
Sbjct: 63 DIADHGWWRRLMEGVGLVVHFAAESHVDRSIESSEAFVRTNVEGTRVLLQAAVDAGVGRF 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG EDHP+ P SPY +K + + +++ YG+ + R N Y
Sbjct: 123 VHISTDEVYGSIAEGSWPEDHPVAPNSPYAATKAASDLLALAYHRTYGLDVRVTRCSNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GPRQ A + +F L G P+ ++GDG +R++++V D LV R G
Sbjct: 183 GPRQYPEKA--VPLFTTNLLDGLPVPLYGDGGNTREWLHVDDHCRGVALVGAGGR-PGVI 239
Query: 232 FNVGTGRETTIIELAMKIIEL-SSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYS 289
+N+G G E T EL +I+EL + S + RPG RR D KI+ +LG+ PR
Sbjct: 240 YNIGGGTELTNAELTDRILELCGADRSALRRVADRPGHDRRYSVDTTKIREELGYAPRTG 299
Query: 290 LEEGLLETWKWFK 302
+ EGL T W++
Sbjct: 300 ITEGLAGTVAWYR 312
>pir||S75550 dTDP-glucose 4-6-dehydratase - Synechocystis sp. (strain PCC 6803)
>gi|1653195|dbj|BAA18111.1| (D90911) dTDP-glucose
4-6-dehydratase [Synechocystis sp.]
Length = 328
Score = 148 bits (369), Expect = 1e-34
Identities = 102/312 (32%), Positives = 161/312 (50%), Gaps = 15/312 (4%)
Query: 6 IVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
I+VTGGAGFIGSH+ + L + ++V+ +DN Y+G N+ + + ++ ++ I
Sbjct: 22 ILVTGGAGFIGSHLIDRLMAQGHEVLCLDNFYTGTKRNIVQWLDNPNFELIRHDVTEPIR 81
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGEPT 124
D V+H A S +PV T + NV+GT+ +L + + AS++ VYG+P
Sbjct: 82 LEVDQVYHLACPASPVHYQFNPVKTIKTNVMGTLYMLGLAKRVGARFLLASTSEVYGDPD 141
Query: 125 SLPIREDH--PLNPISP---YGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
P E + +N I P Y K E +Y+ + V + R FN YGPR
Sbjct: 142 VHPQPESYRGNVNTIGPRACYDEGKRVAETLAFEYYREHKVDIRVARIFNTYGPRMLEND 201
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE---TFNVGT 236
V+S F+ +AL+G+PL +FGDG Q+R F YV D+VE + R G+ N+G
Sbjct: 202 GRVVSNFIVQALQGKPLTVFGDGSQTRSFCYVSDLVEGLM-----RLMNGDYVGPVNLGN 256
Query: 237 GRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLL 295
E TI++LA KI + +++++ D ++ DI K L ++P L++GL
Sbjct: 257 PGEYTILQLAEKIQNAINPDAELIYQPLPEDDPKQRQPDITLAKTYLDWQPTIPLDQGLA 316
Query: 296 ETWKWFKSRTLG 307
T + FKSR G
Sbjct: 317 MTIEDFKSRHEG 328
>pir||C75597 thymidine diphosphoglucose 4,6-dehydratase - Deinococcus
radiodurans (strain R1)
>gi|6460562|gb|AAF12268.1|AE001862_94 (AE001862)
thymidine diphosphoglucose 4,6-dehydratase [Deinococcus
radiodurans]
Length = 364
Score = 148 bits (369), Expect = 1e-34
Identities = 101/317 (31%), Positives = 160/317 (49%), Gaps = 26/317 (8%)
Query: 4 KLIVVTGGAGFIGSHIAE---ALKEENDVVVIDNL-YSGKPENVPE-----GVKFIEADV 54
K ++VTGG GFIGS+ E+ VVV D L Y+G+ EN+ + + + D+
Sbjct: 14 KSLLVTGGCGFIGSNFVRYWLGQHPESKVVVYDKLTYAGRKENLHDLWDNPALSLVVGDI 73
Query: 55 RDYESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLI 112
D + + + D + + AA+ V++S+ P+ E NV GT +L E +L
Sbjct: 74 GDMDLVRRTCQENDVDLIVNFAAETHVDQSILGPLVFTETNVRGTHVLLEVARELGIRLH 133
Query: 113 FASSAAVYGEPTSLPIREDHP------LNPISPYGVSKVSGEHYCKVFYQLYGVPTVILR 166
S+ VYG I++ H L P SPY SK + + + + YG+P I R
Sbjct: 134 HISTDEVYGH-----IKDGHQSVETDELAPRSPYAASKAAADQLVQAYAITYGIPVTITR 188
Query: 167 YFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRR 226
N GP Q A + +F A+ GEPL ++GDG+Q RD+ +V D I R
Sbjct: 189 GANNVGPYQYPEKA--VPLFSTNAILGEPLPVYGDGQQMRDYAHVYDHC-TGIETVLLRG 245
Query: 227 AEGETFNVGTGRETTIIELAMKIIE-LSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFK 285
GE +NVGTGRE T +E+ ++E L S + RPG RR +++K++ LG++
Sbjct: 246 NIGEVYNVGTGREMTNLEMVDIVLETLGKDHSLVKHVTDRPGHDRRYSMNVDKLRSLGWQ 305
Query: 286 PRYSLEEGLLETWKWFK 302
P+Y ++ + E +W++
Sbjct: 306 PKYDPKQAVAEAARWYE 322
>sp|P21977|GALE_STRTR UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|280223|pir||A44509 UDPglucose
4-epimerase (EC 5.1.3.2) - Streptococcus thermophilus
>gi|153749|gb|AAA26944.1| (M38175) UDPglucose
4-epimerase [Streptococcus thermophilus]
Length = 332
Score = 147 bits (368), Expect = 1e-34
Identities = 111/331 (33%), Positives = 171/331 (51%), Gaps = 35/331 (10%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND--VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEI 63
I+V GGAG+IGSH+ + L E+ VVV+D+L +G V F + D+ D + + ++
Sbjct: 3 ILVLGGAGYIGSHMVDRLVEKGQEKVVVVDSLVTGHRAAVHPDAIFYQGDLSDQDFMRKV 62
Query: 64 VSS---ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFASSAAV 119
D V H AA V ES++ P+ + N G + +L ++E K ++F+S+AA
Sbjct: 63 FKENPDVDAVIHFAAYSLVGESMEKPLKYFDNNTAGMVKLLEVMNECGVKYIVFSSTAAT 122
Query: 120 YGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR----- 174
YG P +PI E P NPI+PYG SK+ E K Q YG+ V LRYFNV G
Sbjct: 123 YGIPEEIPILETTPQNPINPYGESKLMMETIMKWSDQAYGIKYVPLRYFNVAGANLMVRL 182
Query: 175 ---QSSAYAGVISIFMERALRGEPLVIFG------DGKQSRDFVYVKDVVEANILVAE-- 223
+S + I + + + +R E ++IFG DG RD+V+ D+ +A++L E
Sbjct: 183 VRTRSETHLLPIILQVAQGVR-EKIMIFGDDYNTPDGTNVRDYVHPFDLADAHLLAVEYL 241
Query: 224 KRRAEGETFNVGTG---RETTIIELAMKIIELSSTSSQILFSKP--RPGDIRRSVADIEK 278
++ E FN+G+ I+E A K+ T +I K RPGD +A EK
Sbjct: 242 RKGNESTAFNLGSSTGFSNLQILEAARKV-----TGKEIPAEKADRRPGDPDILIASSEK 296
Query: 279 IKK-LGFKPRY-SLEEGLLETWKWFKSRTLG 307
+ LG+KP++ ++E+ + W W S G
Sbjct: 297 ARTVLGWKPQFDNIEKIIASAWAWHSSHPKG 327
>sp|P37759|RBB1_ECOLI DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|7437240|pir||H64969 dTDPglucose
4,6-dehydratase (EC 4.2.1.46) - Escherichia coli (strain
K-12) >gi|1736731|dbj|BAA15883.1| (D90841) dTDP-glucose
4,6-dehydratase (EC 4.2.1.46). [Escherichia coli]
>gi|1736744|dbj|BAA15895.1| (D90842) dTDP-glucose
4,6-dehydratase (EC 4.2.1.46). [Escherichia coli]
>gi|1788353|gb|AAC75102.1| (AE000294) dTDP-glucose 4,6
dehydratase [Escherichia coli K12]
>gi|2665489|gb|AAB88398.1| (U09876) dTDP-D-glucose
4,6-dehydratase [Escherichia coli]
Length = 361
Score = 147 bits (368), Expect = 1e-34
Identities = 111/339 (32%), Positives = 169/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVIDNL-YSGKPENVP-----EGVKFIEADVRDY 57
I+VTGGAGFIGS + + ++ VV +D L Y+G E++ E F AD+ D
Sbjct: 3 ILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNRESLADVSDSERYVFEHADICDA 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL----------S 105
++A I + D V H AA+ V+ S+ P E N++GT +L A
Sbjct: 63 PAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSALDSDK 122
Query: 106 EGNGKLIFASSAAVYGE---PTSLPIREDHPL-------NPISPYGVSKVSGEHYCKVFY 155
+ + + S+ VYG+ P + E+ PL P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTAYAPSSPYSASKASSDHLVRAWK 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A V + +A GET+N+G E I++ + I +L S QI + RPG
Sbjct: 241 RALYTVVTEGKA-GETYNIGGHNEKKNIDVVLTICDLLDEIVPKEKSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D EKI + LG+KP+ + E G+ +T +W+ S T
Sbjct: 300 HDRRYAIDAEKIGRALGWKPQETFESGIRKTVEWYLSNT 338
>pir||A69184 UDP-glucose 4-epimerase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621713|gb|AAB85137.1| (AE000844)
UDP-glucose 4-epimerase [Methanobacterium
thermoautotrophicum]
Length = 325
Score = 147 bits (368), Expect = 1e-34
Identities = 107/317 (33%), Positives = 163/317 (50%), Gaps = 22/317 (6%)
Query: 5 LIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEI 63
+I++ GGAG+IGSH+ + L E + +++DNL G + V G +FIE ++ D +
Sbjct: 1 MILIVGGAGYIGSHVNKFLSERGYETLILDNLTRGHRDFVKWG-EFIEGNLGDRRLLDRT 59
Query: 64 VSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAVY 120
+ D V H AA V ESV P NV+ TIN+L ++ + G IF+S+ AVY
Sbjct: 60 FETHDVDAVMHFAAFTDVGESVLKPGRYYHNNVVNTINLLDSMVDHGVRDFIFSSTCAVY 119
Query: 121 GEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP------- 173
G P +PI E+HPLNPISPYG SK+ E + YG+ V LRYFN G
Sbjct: 120 GNPMEIPISEEHPLNPISPYGRSKLMVEEILGDYRDAYGLNYVSLRYFNAAGADPEGEVG 179
Query: 174 RQSSAYAGVISIFMERALRGEPLV-IFG------DGKQSRDFVYVKDVVEAN-ILVAEKR 225
+ +I I ++ AL V IFG DG RD+++V D+ +A+ +
Sbjct: 180 ELHNPETHLIPIVLDVALGLRDAVRIFGTDYPTPDGTCVRDYIHVMDLADAHWRALRYLE 239
Query: 226 RAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGF 284
E FN+G G +++E+ E++ S + RPGD V + ++ LG+
Sbjct: 240 GGESGVFNLGNGNGFSVMEVIETCREVTGASINAVEDDRRPGDPPELVGSAGRARRVLGW 299
Query: 285 KPRYSLEEGLLET-WKW 300
+P ++ E ++ET W W
Sbjct: 300 RPEFTELEDIIETAWNW 316
>gi|7657641 dTDP-D-glucose 4,6-dehydratase [Homo sapiens]
>gi|4128133|emb|CAA06840.1| (AJ006068) dTDP-D-glucose
4,6-dehydratase [Homo sapiens]
>gi|5737699|gb|AAD50061.1|AF048686_1 (AF048686)
dTDP-glucose 4,6-dehydratase like protein [Homo sapiens]
Length = 350
Score = 147 bits (367), Expect = 2e-34
Identities = 104/318 (32%), Positives = 159/318 (49%), Gaps = 22/318 (6%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVVIDNL----YSGKPENVP-----EGVKFIEADV 54
K ++VTGGAGFI SH+ +L E+ +I NL Y +N+ + KFI+ D+
Sbjct: 18 KRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDI 77
Query: 55 RDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKL 111
D + + + D V H AAQ V+ S VNV GT ++ A E K
Sbjct: 78 CDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKF 137
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
I+ S+ VYG E P P +PY SK + E + + +++ Y P VI R NVY
Sbjct: 138 IYVSTDEVYGGSLDKEFDESSPKQPTNPYASSKAAAECFVQSYWEQYKFPVVITRSSNVY 197
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q VI F+ I G G Q+R+F+Y DVVEA + V +K + GE
Sbjct: 198 GPHQYP--EKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFLTVLKKGK-PGEI 254
Query: 232 FNVGTGRETTIIELAMKIIEL-------SSTSSQILFSKPRPGDIRRSVADIEKIKKLGF 284
+N+GT E ++++LA ++I+L S + + + RP + R EKI LG+
Sbjct: 255 YNIGTNFEMSVVQLAKELIQLIKETNSESEMENWVDYVNDRPTNDMRYPMKSEKIHGLGW 314
Query: 285 KPRYSLEEGLLETWKWFK 302
+P+ +EG+ +T +W++
Sbjct: 315 RPKVPWKEGIKKTIEWYR 332
>gb|AAD31800.1|AF128273_3 (AF128273) TDP-glucose-4,6-dehydratase homolog [Streptomyces
griseus]
Length = 324
Score = 146 bits (366), Expect = 2e-34
Identities = 101/312 (32%), Positives = 166/312 (52%), Gaps = 17/312 (5%)
Query: 6 IVVTGGAGFIGSHIAEAL-------KEENDVVVIDNL-YSGKPENVP---EGVKFIEADV 54
I+VTGGAGFIGSH A +L + + V+D L Y+G N+P + ++F+ DV
Sbjct: 3 ILVTGGAGFIGSHYARSLLAGRYGAAPDTRITVLDKLTYAGDRGNLPAHHDRLEFVRGDV 62
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIF 113
D + E++ D + H AA+ V+ SV N +GT +L A S +++
Sbjct: 63 CDGALLRELLPGHDAIVHFAAESHVDRSVAGGREFVRTNALGTQVLLEAASLSRVERVLH 122
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S+ VYG E+ PL P SPY SK S + + +++ +G+ I R N YGP
Sbjct: 123 ISTDEVYGSIEQGSWTEERPLLPNSPYAASKASADLIARSYWRTHGLDVSITRCSNNYGP 182
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
Q ++ F+ LRG + ++GDG+ R++++V D A LV K A GE +N
Sbjct: 183 YQHP--EKLVPRFVTNLLRGRKVPVYGDGRNRREWIHVDDHCRAIHLVLAKGGA-GEIYN 239
Query: 234 VGTGRETTIIELAMKIIEL-SSTSSQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYSLE 291
VG+G E + LA ++ L + +S I + + R G D+R ++ D + ++LG++P+ L+
Sbjct: 240 VGSGDELENLRLAEHLLALCGADASMIEYVEDRKGHDLRYALDDTKIREQLGYEPQVPLD 299
Query: 292 EGLLETWKWFKS 303
G+ ET W+++
Sbjct: 300 RGIAETVAWYEA 311
>gb|AAF00211.1|AF164960_7 (AF164960) dNDP-glucose 4,6-dehydratase [Streptomyces fradiae]
Length = 328
Score = 146 bits (365), Expect = 3e-34
Identities = 101/311 (32%), Positives = 157/311 (50%), Gaps = 17/311 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-------DVVVIDNL-YSGKPENVPEG---VKFIEADV 54
I+VTG AGFIGSH +L + V +D L Y+G N+P ++F+ DV
Sbjct: 3 ILVTGAAGFIGSHFVRSLLADTYSGWEGARVTALDKLTYAGNRNNLPPSNPRLEFVRGDV 62
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKLIF 113
D + E++ V H AA+ V+ S++ NV+GT +L A L G +++
Sbjct: 63 CDRALLRELLPGHHAVVHFAAESHVDRSLEGAGEFFRTNVLGTQTLLDAVLDSGVERVVH 122
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S+ VYG ED PL P SPY SK + + + V I R N YGP
Sbjct: 123 VSTDEVYGSIEQGSWTEDWPLQPNSPYAASKACSDLVARAYCAPTEVDLSITRCSNNYGP 182
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
Q VI F+ L G + ++GDG+ R++++V+D LV K +A GE +N
Sbjct: 183 HQHP--EKVIPRFVTNLLEGRQVPLYGDGRNVREWLHVEDHCRGIHLVLNKGQA-GEIYN 239
Query: 234 VGTGRETTIIELAMKIIELSSTSSQILFSKP--RPGDIRRSVADIEKIKKLGFKPRYSLE 291
+G G E T + L K++EL+ +++ P + D+R S+ + + +KLG+ PR S E
Sbjct: 240 IGGGNEYTNLALTEKLLELTGAGPEMIRRVPDRKAHDLRYSIDESKIREKLGYAPRISFE 299
Query: 292 EGLLETWKWFK 302
+GL +T W++
Sbjct: 300 QGLSDTVAWYR 310
>gb|AAF36926.1|AF221951_2 (AF221951) putative UDP-galactose 4-epimerase GalE [Rhodococcus
erythropolis]
Length = 329
Score = 146 bits (365), Expect = 3e-34
Identities = 107/319 (33%), Positives = 171/319 (53%), Gaps = 24/319 (7%)
Query: 6 IVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++VTGGAG++GS + L E ++VVVID+L +G + VP G +FIE DV A+++
Sbjct: 3 LLVTGGAGYVGSVCSTVLLERGHEVVVIDDLSTGNADAVPAGAEFIEGDVGALA--ADVL 60
Query: 65 SSA-----DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS-EGNGKLIFASSAA 118
SA D V H AAQ V ESV P NV+ TI +L A+ G +L+F+S+AA
Sbjct: 61 GSAGSPVFDGVLHFAAQSLVGESVLHPEKYWRGNVVTTIELLEAIRVSGTPRLVFSSTAA 120
Query: 119 VYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSA 178
YGEP PI E P P +PYG +K++ +H + +G+ LRYFNV G +S+
Sbjct: 121 TYGEPEQSPIVETAPTRPTNPYGATKLAIDHAITSYSIAHGLGATSLRYFNVAGAYKSAG 180
Query: 179 YAGVIS-----IFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKR- 225
VI + ++ AL + + + +FG DG RD+++V D+ EA++L E
Sbjct: 181 ENRVIETHLIPLVLQVALEQRDKISVFGTDWPTPDGTAVRDYIHVLDLAEAHLLALESSV 240
Query: 226 RAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEK-IKKLGF 284
E +N+G+G ++ E+ ++ + + R GD +A +K I +LG+
Sbjct: 241 PGEHRIYNLGSGAGFSVREVIAACARVTGLPINVEDASRRLGDPAVLIASSDKAIAELGW 300
Query: 285 KP-RYSLEEGLLETWKWFK 302
P R L+ + + W++ +
Sbjct: 301 TPTRTDLDVIVADAWQFLQ 319
>emb|CAB87338.1| (AL163672) UDP-glucose 4-epimerase [Streptomyces coelicolor A3(2)]
Length = 326
Score = 146 bits (364), Expect = 4e-34
Identities = 100/310 (32%), Positives = 159/310 (51%), Gaps = 18/310 (5%)
Query: 7 VVTGGAGFIGSHIAEALKEEND-VVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIVS 65
++TGGAG+IG+H+ A+ E + VV D+L +G E VP+GV + V D E +A ++
Sbjct: 4 LITGGAGYIGAHVVRAMTEAGEKAVVYDDLSTGIAERVPDGVPLVVGSVLDGERVARALA 63
Query: 66 --SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAVYGE 122
S V H AA+ V ESV P+ NV G +L A++ G +F+SSAAVYG
Sbjct: 64 DHSVTGVVHLAAKKQVGESVDLPLHYYRQNVEGLRVLLDAVTAAGVPSFVFSSSAAVYGM 123
Query: 123 PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ----SSA 178
P + E+ P P+SPYG +K++GE + + G+ T LRYFNV G +
Sbjct: 124 PDVDLVTEETPCVPMSPYGETKLAGEWLVRATGRATGLATASLRYFNVAGAASPDLVDTG 183
Query: 179 YAGVISIFMERALRGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKRRAE---G 229
++ + E+ IFG DG RD+++V D+ EA++ A ++
Sbjct: 184 VYNLVPMVFEKLTESAAPRIFGDDYATPDGTCVRDYIHVVDLAEAHVAAARALQSSPGTA 243
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRY 288
T N+G G ++ E+ +I ++ + RPGD R VA ++ +LG+K +Y
Sbjct: 244 LTLNIGRGEGVSVREMIDRINAVTGCDQPPTVTPRRPGDPARVVASADRAAVELGWKAKY 303
Query: 289 SLEEGLLETW 298
+E+ + W
Sbjct: 304 DVEDMITSAW 313
>emb|CAB95930.1| (AL359989) UDP-glucose 4-epimerase [Streptomyces coelicolor A3(2)]
Length = 321
Score = 146 bits (364), Expect = 4e-34
Identities = 108/315 (34%), Positives = 162/315 (51%), Gaps = 19/315 (6%)
Query: 7 VVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIVS 65
+VTGGAG++GS +A+ L E ++VVV+DNL +G E VP G F+E D+RD +
Sbjct: 6 LVTGGAGYVGSVVAQHLVEAGHEVVVLDNLSTGFREGVPAGASFVEGDIRDAAKWLD--G 63
Query: 66 SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGNGKLIFASSAAVYGEPT 124
S D V H AA V ESV P + NV GT+ +L A+ G +L+F+S+AA YGEP
Sbjct: 64 SFDGVLHFAAFSQVGESVVKPEKYWDNNVGGTMALLEAMRGAGVRRLVFSSTAATYGEPE 123
Query: 125 SLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV------YGPRQSSA 178
+PI E P P +PYG SK++ +H +G+ V LRYFNV YG R
Sbjct: 124 QVPIVESAPTRPTNPYGASKLAVDHMITGEAAAHGLGAVSLRYFNVAGAYGEYGERHDPE 183
Query: 179 YAGVISIFMERALRGEPLVIFG------DGKQSRDFVYVKDVVEANIL-VAEKRRAEGET 231
+ + R E + ++G DG RD+++V D+ EA++L VA E
Sbjct: 184 SHLIPLVLQVAQGRREAISVYGDDYPTPDGTCVRDYIHVADLAEAHLLAVAAAAPGEHLI 243
Query: 232 FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKP-RYS 289
N+G G ++ E+ + ++ + + R GD VA + KLG+ P R
Sbjct: 244 CNLGNGNGFSVREVVETVRRVTGHPIPEIMAPRRGGDPAVLVASAGTAREKLGWNPSRAD 303
Query: 290 LEEGLLETWKWFKSR 304
L + + W++ + R
Sbjct: 304 LAGIVSDAWEFAQRR 318
>sp|P33119|GALE_CORDI UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|144973|gb|AAA23297.1| (M34239) ORF3
[Corynebacterium diphtheriae] >gi|144977|gb|AAA23300.1|
(M80338) open reading frame [Corynebacterium
diphtheriae]
Length = 328
Score = 145 bits (363), Expect = 5e-34
Identities = 96/310 (30%), Positives = 164/310 (51%), Gaps = 17/310 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++VTGGAG++GS + L E+ ++V ++DNL +G + VP G F+E D++D
Sbjct: 3 LLVTGGAGYVGSVCSTVLLEQGHEVTIVDNLTTGNRDAVPLGATFVEGDIKDVAENVLSS 62
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFASSAAVYGEP 123
S D V H AA+ V ESV+ P + N++ T+ +L A+ N + ++F+S+AA YGEP
Sbjct: 63 DSFDAVLHFAARSLVGESVEKPDEYWQHNMVTTLALLDAMKRNNVRNIVFSSTAATYGEP 122
Query: 124 TSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP-----RQSSA 178
++PI ED P +P +PYG +K+S ++ + YG LRYFNV G
Sbjct: 123 ETVPITEDAPTHPTNPYGATKLSIDYAITSYAHAYGFAATSLRYFNVAGAYGLVGENREI 182
Query: 179 YAGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKR-RAEGE 230
+I + ++ AL + + +FG DG RD+++++D+ +A+IL +
Sbjct: 183 ETHLIPLVLQVALGHRDKIFMFGDDWPTEDGTPIRDYIHIRDLADAHILALQSNVEGSHR 242
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKP-RY 288
FN+G+G ++ ++ E++ + R GD +A K + +LG+KP R
Sbjct: 243 IFNLGSGEGYSVKQVIDTCREVTGHPIPAEVAPRRAGDPAVLIASSAKAQSELGWKPQRT 302
Query: 289 SLEEGLLETW 298
L + + W
Sbjct: 303 DLHTIVSDAW 312
>pir||S75783 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) - Synechocystis sp.
(strain PCC 6803) >gi|1001273|dbj|BAA10518.1| (D64003)
dTDP-glucose 4,6-dehydratase [Synechocystis sp.]
Length = 342
Score = 145 bits (363), Expect = 5e-34
Identities = 106/329 (32%), Positives = 164/329 (49%), Gaps = 37/329 (11%)
Query: 6 IVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKP------ENVPEGVKFIEADVR 55
I+VTGGAGFIG++ + + +VV+D L Y+G E +P +F++ D+
Sbjct: 6 ILVTGGAGFIGANFVYHCVQTCGDRRIVVLDALTYAGNRATLAPLEKLPN-FRFVQGDIG 64
Query: 56 DYESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-----GN 108
D + +++ + + H AA+ V+ S+ P + NV+GT +L A E GN
Sbjct: 65 DRHLVDQLLREEQIETIAHFAAESHVDRSILGPGAFVQTNVVGTFTLLEAFREHWQRRGN 124
Query: 109 G---KLIFASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTV 163
+ + S+ VYG P E P +P SPY SK +H + ++ YG+PT+
Sbjct: 125 PAQFRFLHVSTDEVYGSLTPNEPGFSETTPYSPNSPYSASKAGSDHLVRAYFHTYGLPTL 184
Query: 164 ILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAE 223
I N YGP Q +I + LRGE L ++GDG+ RD++YV D +A LV
Sbjct: 185 ITNCSNNYGPYQFP--EKLIPLMCLNILRGEKLPVYGDGQNVRDWLYVTDHCQALDLVLH 242
Query: 224 KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKP----------RPGDIRRSV 273
+ G T+N+G E IEL + +L + L KP RPG RR
Sbjct: 243 -QALPGATYNIGGNNEVKNIELVEILCDLMDELAPDLPVKPARQLISYVTDRPGHDRRYA 301
Query: 274 ADIEKIKK-LGFKPRYSLEEGLLETWKWF 301
D KIK+ LG++P+ ++E GL +T +W+
Sbjct: 302 IDASKIKRELGWEPKVTVERGLRQTVQWY 330
>gb|AAC68681.1| (AF079762) TDP-glucose-4,6-dehydratase [Streptomyces venezuelae]
Length = 337
Score = 145 bits (362), Expect = 6e-34
Identities = 101/313 (32%), Positives = 160/313 (50%), Gaps = 19/313 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKE-------ENDVVVIDNL-YSGK-----PENVPEGVKFIEA 52
++VTGGAGFIGSH L ++V+V+D+L Y+G P + ++F+
Sbjct: 3 LLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHG 62
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-ALSEGNGKL 111
D+RD +A + D + H AA+ V+ S+ E NV GT +L+ A+ G G++
Sbjct: 63 DIRDAGLLARELRGVDAIVHFAAESHVDRSIAGASVFTETNVQGTQTLLQCAVDAGVGRV 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG S E PL P SPY SK + + +++ YG+ I R N Y
Sbjct: 123 VHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHRTYGLDVRITRCCNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q +I +F+ L G L ++GDG R++V+ D LV RA GE
Sbjct: 183 GPYQHP--EKLIPLFVTNLLDGGTLPLYGDGANVREWVHTDDHCRGIALVLAGGRA-GEI 239
Query: 232 FNVGTGRETTIIELAMKIIE-LSSTSSQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYS 289
+++G G E T EL +++ L + S + R G D+R S+ E ++LG++P+ S
Sbjct: 240 YHIGGGLELTNRELTGILLDSLGADWSSVRKVADRKGHDLRYSLDGGEIERELGYRPQVS 299
Query: 290 LEEGLLETWKWFK 302
+GL T +W++
Sbjct: 300 FADGLARTVRWYR 312
>sp|P55180|GALE_BACSU UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|7437225|pir||D69628 UDPglucose
4-epimerase (EC 5.1.3.2) - Bacillus subtilis
>gi|1429254|emb|CAA67713.1| (X99339) UDP-glucose
4-epimerase [Bacillus subtilis]
>gi|1783241|dbj|BAA11718.1| (D83026) highly homologous
to UDP-glucose 4-epimerases (SwissProt:GALE_HAEIN and
GALE_ECOLI); hypothetical [Bacillus subtilis]
>gi|2636421|emb|CAB15912.1| (Z99123) UDP-glucose
4-epimerase [Bacillus subtilis]
Length = 339
Score = 145 bits (361), Expect = 8e-34
Identities = 106/332 (31%), Positives = 166/332 (49%), Gaps = 30/332 (9%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENV-------PEGVKFIEADVRDY 57
I+VTGGAG+IGSH E L ++VV+DNL + E + + + F EAD+ D
Sbjct: 3 ILVTGGAGYIGSHTCVELLNSGYEIVVLDNLSNSSAEALNRVKEITGKDLTFYEADLLDR 62
Query: 58 ESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
E++ + + + V H A +V ESV P+ N+ GT + A+ + G K++F+
Sbjct: 63 EAVDSVFAENEIEAVIHFAGLKAVGESVAIPLKYYHNNLTGTFILCEAMEKYGVKKIVFS 122
Query: 115 SSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTV-ILRYFNVYGP 173
SSA VYG P + PI ED PL +PYG +K+ E + + +V +LRYFN +G
Sbjct: 123 SSATVYGVPETSPITEDFPLGATNPYGQTKLMLEQILRDLHTADNEWSVALLRYFNPFGA 182
Query: 174 RQSSAYA----GVISIFMERAL-----RGEPLVIFG------DGKQSRDFVYVKDVVEAN 218
S G+ + M + E L +FG DG RD+++V D+ E +
Sbjct: 183 HPSGRIGEDPNGIPNNLMPYVAQVAVGKLEQLSVFGNDYPTKDGTGVRDYIHVVDLAEGH 242
Query: 219 ILVAEK--RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADI 276
+ EK + +N+GTG +++E+ ++S F+ RPGDI AD
Sbjct: 243 VKALEKVLNSTGADAYNLGTGTGYSVLEMVKAFEKVSGKEVPYRFADRRPGDIATCFADP 302
Query: 277 EKIKK-LGFKPRYSLEEGLLETWKWFKSRTLG 307
K K+ LG++ + LEE ++W+W S G
Sbjct: 303 AKAKRELGWEAKRGLEEMCADSWRWQSSNVNG 334
>sp|O65781|GAE2_CYATE UDP-GLUCOSE 4-EPIMERASE GEPI48 (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|7437270|pir||T10498 UDPglucose
4-epimerase (EC 5.1.3.2) (clone GEPI48) - guar
>gi|3021357|emb|CAA06339.1| (AJ005082) UDP-galactose
4-epimerase [Cyamopsis tetragonoloba]
Length = 350
Score = 144 bits (360), Expect = 1e-33
Identities = 103/342 (30%), Positives = 170/342 (49%), Gaps = 36/342 (10%)
Query: 1 MRNKLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVPE----------GVKF 49
M ++ ++VTGGAG+IGSH + + L VV+DNL + + + F
Sbjct: 1 MSSQTVLVTGGAGYIGSHTVLQLLLGGFKAVVVDNLDNSSETAIHRVKELAGKFAGNLSF 60
Query: 50 IEADVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS-E 106
+ D+RD +++ +I SS D V H A +V ESV+ P+ + N+IGTI + ++
Sbjct: 61 HKLDLRDRDALEKIFSSTKFDSVIHFAGLKAVGESVQKPLLYYDNNLIGTIVLFEVMAAH 120
Query: 107 GNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQL-YGVPTVIL 165
G KL+F+SSA VYG P +P E+ PL+ +PYG +K+ E C+ Y+ ++L
Sbjct: 121 GCKKLVFSSSATVYGLPKEVPCTEEFPLSAANPYGRTKLIIEEICRDIYRAEQEWKIILL 180
Query: 166 RYFNVYGPRQSSAYAGV--------ISIFMERALRGE--PLVIFG------DGKQSRDFV 209
RYFN G S Y G + F+++ G L +FG DG RD++
Sbjct: 181 RYFNPVG-AHPSGYIGEDPRGIPNNLMPFVQQVAVGRRPALTVFGNDYTTSDGTGVRDYI 239
Query: 210 YVKDVVEANILVAEK---RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRP 266
+V D+ + +I K + E +N+GTG+ T+++E+ + S ++ + RP
Sbjct: 240 HVVDLADGHIAALRKLNDPKIGCEVYNLGTGKGTSVLEMVKAFEQASGKKIPLVMAGRRP 299
Query: 267 GDIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
GD A K ++L +K +Y ++E + W W G
Sbjct: 300 GDAEVVYASTNKAERELNWKAKYGIDEMCRDQWNWASKNPYG 341
>sp|P26391|RFBB_SALTY DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|96840|pir||S15299 dTDPglucose
4,6-dehydratase (EC 4.2.1.46) - Salmonella typhimurium
>gi|581654|emb|CAA40115.1| (X56793) dTDP-glucose
4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 144 bits (359), Expect = 1e-33
Identities = 112/339 (33%), Positives = 167/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
N + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+PL I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALHMVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANT 338
>gb|AAF13998.1|AF201913_1 (AF201913) SgcA [Streptomyces globisporus]
Length = 332
Score = 144 bits (359), Expect = 1e-33
Identities = 105/312 (33%), Positives = 153/312 (48%), Gaps = 19/312 (6%)
Query: 6 IVVTGGAGFIGSHIAEAL-------KEENDVVVIDNL-YSGKPENVPEGVK-----FIEA 52
++VTGGAGFIGS A E+ V V+D L YSG P N+ F++
Sbjct: 3 MLVTGGAGFIGSQFVRATLHGELPGSEDARVTVLDKLTYSGNPANLTSVAAHPRYTFVQG 62
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKL 111
D D + E+V+ D + H AA+ V+ S+ NV+GT +L A L G G+
Sbjct: 63 DTVDPRVVDEVVAGHDVIVHFAAESHVDRSIDTATRFVTTNVLGTQTLLEAALRHGVGRF 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG S ED PL P PY SK + +++ G+ V+ R N Y
Sbjct: 123 VHVSTDEVYGSIASGSWTEDTPLAPNVPYAASKAGSDLMALAWHRTRGLDVVVTRCTNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q VI +F+ L G + ++GDG RD+++V D A +V RA GE
Sbjct: 183 GPYQYP--EKVIPLFVTNILDGLRVPLYGDGAHRRDWLHVSDHCRAIQMVMNSGRA-GEV 239
Query: 232 FNVGTGRETTIIELAMKIIELSSTS-SQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYS 289
+++G G E + EL ++ T S + R G RR DI KI+ +LG++P +
Sbjct: 240 YHIGGGTELSNEELTGLLLTACGTDWSCVDRVADRQGHDRRYSLDITKIRQELGYEPLVA 299
Query: 290 LEEGLLETWKWF 301
E+GL T KW+
Sbjct: 300 FEDGLAATVKWY 311
>pir||T30873 dNDP-glucose dehydratase - Streptomyces viridochromogenes
>gi|1911170|emb|CAA72715.1| (Y11985) dNDP-glucose
dehydratase [Streptomyces viridochromogenes]
Length = 355
Score = 143 bits (358), Expect = 2e-33
Identities = 99/309 (32%), Positives = 154/309 (49%), Gaps = 12/309 (3%)
Query: 2 RNKLIVVTGGAGFIGSHIAEALKEEND---VVVIDNL-YSGKPEN---VPEGVKFIEADV 54
R + ++V GGAGFIGS L + D V V+D L Y+G N V F+ D+
Sbjct: 10 RGRHVLVIGGAGFIGSQYVRELVRDGDPARVTVLDKLTYAGNLANLEPVAGRYTFVHGDI 69
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA-LSEGNGKLIF 113
D +AE+V D V + AA+ V+ S+ D NV G +++ L G +++
Sbjct: 70 CDARLLAEVVPGHDLVVNFAAESHVDRSIADAAPFIRTNVQGVQALMQVCLEAGTARIVQ 129
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S+ VYG + ED P+ P SPY SK G+ + + +G+P + R N YGP
Sbjct: 130 VSTDEVYGSIETGSWDEDAPIAPNSPYAASKAGGDMVALAYARTHGLPVSVTRCGNNYGP 189
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
Q V+ +F R L G + ++GDG RD+V+V D V LVAE R G+ ++
Sbjct: 190 YQFP--EKVVPLFTTRLLDGHSIPLYGDGGNVRDWVHVSDHVRGIRLVAE-RGLPGQVYH 246
Query: 234 VGTGRETTIIELAMKIIE-LSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSLEE 292
+ E T +EL ++++ L + ++ R G RR ++ LG+ PR S E+
Sbjct: 247 IAGSAELTNLELTQQLLDALGAGWDRVERVPDRKGHDRRYSLCDARLGALGYAPRVSFEQ 306
Query: 293 GLLETWKWF 301
GL +T +W+
Sbjct: 307 GLADTVRWY 315
>gb|AAG09498.1|AF279615_1 (AF279615) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
>gi|9957820|gb|AAG09502.1|AF279616_1 (AF279616)
dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 143 bits (358), Expect = 2e-33
Identities = 112/339 (33%), Positives = 167/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
N + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+PL I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALHMVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANT 338
>gb|AAG09509.1|AF279618_1 (AF279618) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 143 bits (358), Expect = 2e-33
Identities = 112/339 (33%), Positives = 167/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
N + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+PL I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALHMVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKTTSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANT 338
>gb|AAG09517.1|AF279620_1 (AF279620) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 143 bits (358), Expect = 2e-33
Identities = 112/339 (33%), Positives = 167/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS I +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVIRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+PL I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDYA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALYIVVTEGKA-GETYNIGGHNEKKNVDVVFTICDLLDEIVPKAASYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANT 338
>pir||T04291 probable UDPglucose 4-epimerase (EC 5.1.3.2) - Arabidopsis thaliana
>gi|4539370|emb|CAB40064.1| (AL049525) UDP-galactose
4-epimerase-like protein [Arabidopsis thaliana]
>gi|7267794|emb|CAB81197.1| (AL161518) UDP-galactose
4-epimerase-like protein [Arabidopsis thaliana]
Length = 351
Score = 143 bits (357), Expect = 2e-33
Identities = 101/344 (29%), Positives = 171/344 (49%), Gaps = 40/344 (11%)
Query: 1 MRNKLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP----------EGVKF 49
M + ++V+GGAG+IGSH + + L VVV+DNL + ++ E + F
Sbjct: 1 MMARNVLVSGGAGYIGSHTVLQLLLGGYSVVVVDNLDNSSAVSLQRVKKLAAEHGERLSF 60
Query: 50 IEADVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE- 106
+ D+RD ++ +I S D V H A +V ESV+ P+ N++GTI +L +++
Sbjct: 61 HQVDLRDRSALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNLVGTITLLEVMAQH 120
Query: 107 GNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV----PT 162
G L+F+SSA VYG P +P E+ P++ ++PYG +K+ E C+ +YG
Sbjct: 121 GCKNLVFSSSATVYGSPKEVPCTEEFPISALNPYGRTKLFIEEICR---DVYGSDPEWKI 177
Query: 163 VILRYFNVYGPRQSSAYA--------GVISIFMERALRGEP-LVIFG------DGKQSRD 207
++LRYFN G S ++ + A+ P L +FG DG RD
Sbjct: 178 ILLRYFNPVGAHPSGDIGEDPRGIPNNLMPFVQQVAVGRRPHLTVFGNDYNTKDGTGVRD 237
Query: 208 FVYVKDVVEANILVAEKR---RAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKP 264
+++V D+ + +I K + E +N+GTG T+++E+ + S ++ +
Sbjct: 238 YIHVIDLADGHIAALRKLEDCKIGCEVYNLGTGNGTSVLEMVDAFEKASGKKIPLVIAGR 297
Query: 265 RPGDIRRSVADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
RPGD A E+ + +L +K +Y +EE + W W + G
Sbjct: 298 RPGDAEVVYASTERAESELNWKAKYGIEEMCRDLWNWASNNPYG 341
>pir||S58686 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) graE - Streptomyces
violaceoruber >gi|763511|gb|AAA99939.1| (L37334)
dTDP-glucose dehydratase [Streptomyces violaceoruber]
>gi|4218549|emb|CAA09638.1| (AJ011500) putative
dTDP-glucose-4,6-dehydratase [Streptomyces
violaceoruber]
Length = 321
Score = 143 bits (356), Expect = 3e-33
Identities = 104/311 (33%), Positives = 162/311 (51%), Gaps = 17/311 (5%)
Query: 6 IVVTGGAGFIGSH-----IAEALKEENDV--VVIDNL-YSGKPENVPEG---VKFIEADV 54
++VTG AGFIGSH +A + E +DV V+D L Y+G+ +N+PE + F+ D+
Sbjct: 3 LLVTGAAGFIGSHYVREILAGSYPESDDVHVTVVDRLTYAGRRDNLPEHHERLDFVHGDI 62
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGKLIF 113
D + + ++ D V H AA+ V+ S+ P NV+GT +L AL G +++
Sbjct: 63 CDRDLLDRVLPGHDAVVHFAAESHVDRSLTGPGEFVRTNVMGTQQLLDAALHAGVDRVLH 122
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S+ VYG S ED PL P SPY SK S +G+ I R N YGP
Sbjct: 123 VSTDEVYGSLDSGTWTEDSPLLPNSPYAASKASTTWSAAPTTVRHGLDVRITRCSNNYGP 182
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
RQ +I F+ R L G + ++GDG+ R++++V D A LV K RA GE +N
Sbjct: 183 RQHP--EKLIPNFVTRLLTGRQVPLYGDGRNVREWLHVDDHCRALQLVLTKGRA-GEIYN 239
Query: 234 VGTGRETTIIELAMKIIELSSTS-SQILFSKPRPG-DIRRSVADIEKIKKLGFKPRYSLE 291
+G G + E+ ++++L + + R G D R ++ D + ++LG+ PR+S+E
Sbjct: 240 IGGGSGMSNREMTARLLDLLGADWDMVRHVEDRLGHDFRYAIDDSKIREELGYAPRWSIE 299
Query: 292 EGLLETWKWFK 302
GL W++
Sbjct: 300 SGLGAVVDWYR 310
>sp|P96995|GALE_STRMU UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|7437233|pir||JC5313 UDPglucose
4-epimerase (EC 5.1.3.2) - Streptococcus mutans
>gi|1877424|gb|AAB49738.1| (U21942) UDP-galactose
4-epimerase [Streptococcus mutans]
Length = 333
Score = 143 bits (356), Expect = 3e-33
Identities = 110/331 (33%), Positives = 167/331 (50%), Gaps = 34/331 (10%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEI 63
I+V GGAG+IGSH+ + L K E +VVV+D+L +G V KF + D+ D E ++ +
Sbjct: 3 ILVLGGAGYIGSHMVDRLIEKGEEEVVVVDSLVTGHRAAVHPAAKFYQGDLADREFMSMV 62
Query: 64 VSS---ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFASSAAV 119
D V H AA V ES+K P+ + N G I +L +SE K ++F+S+AA
Sbjct: 63 FRENPDVDAVIHFAAYSLVAESMKKPLKYFDNNTAGMIKLLEVMSEFGVKYIVFSSTAAT 122
Query: 120 YGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPR----- 174
YG P +PI+E P PI+PYG SK+ E K + YG+ V +RYFNV G +
Sbjct: 123 YGIPNEIPIKETTPQRPINPYGESKLMMETIMKWSDRAYGIKFVPVRYFNVAGAKPDGSI 182
Query: 175 --QSSAYAGVISIFMERALR-GEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKR 225
S ++ I ++ A E ++IFG DG RD+V+ D+ + ++L
Sbjct: 183 GEDHSPETHLLPIILQVAQGVREKIMIFGDDYNTPDGTNVRDYVHPFDLADRHLLALNYL 242
Query: 226 RA--EGETFNVGTG---RETTIIELAMKIIELSSTSSQILFSKP--RPGDIRRSVADIEK 278
R FN+G+ I+E A K+ T +I K R GD +A EK
Sbjct: 243 RQGNPSTAFNLGSSTGFSNLQILEAARKV-----TGQKIPAEKAARRSGDPDTLIASSEK 297
Query: 279 IKK-LGFKPRY-SLEEGLLETWKWFKSRTLG 307
++ +G+KP++ +E+ + W W S G
Sbjct: 298 AREVVGWKPQFDDIEKIIASAWAWHSSHPKG 328
>pir||G71151 probable dTDP-glucose 4,6-dehydratase - Pyrococcus horikoshii
>gi|3256817|dbj|BAA29500.1| (AP000002) 336aa long
hypothetical dTDP-glucose 4,6-dehydratase [Pyrococcus
horikoshii]
Length = 336
Score = 143 bits (356), Expect = 3e-33
Identities = 100/314 (31%), Positives = 161/314 (50%), Gaps = 16/314 (5%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEEN---DVVVIDNL-YSGKPENVPE-----GVKFIE 51
M + ++VTGG GFIGS+ + E++ +V+ ID L Y P N+ + F++
Sbjct: 1 MHSMKLLVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVK 60
Query: 52 ADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKL 111
DV DYE + E+V D V H AA+ V+ S+ P NVIGT +L ++ N ++
Sbjct: 61 GDVADYELVKELVRKVDGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRRENPEV 120
Query: 112 IF--ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
F S+ VYG+ E+ L P SPY +K + + + + Y + I R N
Sbjct: 121 RFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRTYNLNASITRCTN 180
Query: 170 VYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG 229
YGP Q +I + RA G + I+G GK RD++YV+D V A LV K +
Sbjct: 181 NYGPYQFP--EKLIPKTIIRASLGLKIPIYGTGKNVRDWLYVEDHVRAIELVLLKGESR- 237
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQIL-FSKPRPG-DIRRSVADIEKIKKLGFKPR 287
E +N+ G E T +E+ I+ L +++ + RPG D+R S+ + + L ++P+
Sbjct: 238 EIYNISAGEEKTNLEVVKIILRLMGKGEELIELVEDRPGHDLRYSLDSWKITRDLKWRPK 297
Query: 288 YSLEEGLLETWKWF 301
Y+ +EG+ +T W+
Sbjct: 298 YTFDEGIKKTIDWY 311
>pir||T01881 UDPglucose 4-epimerase (EC 5.1.3.2) F8M12.10 - Arabidopsis thaliana
>gi|3513739|gb|AAC33955.1| (AF080118) Similar to uridine
diphosphate glucose epimerase; F8M12.10 [Arabidopsis
thaliana]
Length = 350
Score = 143 bits (356), Expect = 3e-33
Identities = 100/339 (29%), Positives = 169/339 (49%), Gaps = 40/339 (11%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP----------EGVKFIEADV 54
++V+GGAG+IGSH + + L VVV+DNL + ++ E + F + D+
Sbjct: 5 VLVSGGAGYIGSHTVLQLLLGGYSVVVVDNLDNSSAVSLQRVKKLAAEHGERLSFHQVDL 64
Query: 55 RDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKL 111
RD ++ +I S D V H A +V ESV+ P+ N++GTI +L +++ G L
Sbjct: 65 RDRSALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNLVGTITLLEVMAQHGCKNL 124
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV----PTVILRY 167
+F+SSA VYG P +P E+ P++ ++PYG +K+ E C+ +YG ++LRY
Sbjct: 125 VFSSSATVYGSPKEVPCTEEFPISALNPYGRTKLFIEEICR---DVYGSDPEWKIILLRY 181
Query: 168 FNVYGPRQSSAYA--------GVISIFMERALRGEP-LVIFG------DGKQSRDFVYVK 212
FN G S ++ + A+ P L +FG DG RD+++V
Sbjct: 182 FNPVGAHPSGDIGEDPRGIPNNLMPFVQQVAVGRRPHLTVFGNDYNTKDGTGVRDYIHVI 241
Query: 213 DVVEANILVAEKR---RAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
D+ + +I K + E +N+GTG T+++E+ + S ++ + RPGD
Sbjct: 242 DLADGHIAALRKLEDCKIGCEVYNLGTGNGTSVLEMVDAFEKASGKKIPLVIAGRRPGDA 301
Query: 270 RRSVADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
A E+ + +L +K +Y +EE + W W + G
Sbjct: 302 EVVYASTERAESELNWKAKYGIEEMCRDLWNWASNNPYG 340
>pir||D81275 probable nucleotide sugar dehydratase Cj1319 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968753|emb|CAB73746.1| (AL139078) putative
nucleotide sugar dehydratase [Campylobacter jejuni]
Length = 323
Score = 142 bits (355), Expect = 4e-33
Identities = 101/315 (32%), Positives = 161/315 (51%), Gaps = 18/315 (5%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYS-----GKPENVP--EGVKFIEAD 53
MRN I+VTG GFIGSH+ E+L ++ V + Y+ G E P + ++ I D
Sbjct: 1 MRN--ILVTGADGFIGSHLCESLVKKGFKVRALSQYNSFNFWGHLEKSPFLKDMEVISGD 58
Query: 54 VRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLI 112
+RD +I + D +FH A I++ S P + NV GT+N+L A + I
Sbjct: 59 LRDSFFCEKITKNIDAIFHLGALIAIPYSYTAPQSYVDTNVNGTLNMLEAAKKNEISHFI 118
Query: 113 FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
S++ VYG +PI E HPL P SPY SK++ + +Y + + I R FN YG
Sbjct: 119 HTSTSEVYGTAFYVPIDEKHPLQPQSPYSASKIAADMMALSYYNSFNLNVNIARPFNTYG 178
Query: 173 PRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF 232
PRQS+ +I + + L G + GD RD +V D E I + + GE +
Sbjct: 179 PRQSA--RAIIPTIITQILSGAKEIKLGDLSPKRDLNFVLDTCEGFISLLNLKHF-GEVY 235
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFS----KPRPGDIRRSVADIEKIKK-LGFKPR 287
N+G+G E ++ E+ I ++ + +I+ +P+ ++ R D K+KK ++ +
Sbjct: 236 NIGSGVEYSMQEVLDLIQKILDSKVKIIQDEQRLRPKNSEVFRLCCDANKLKKATNWQSK 295
Query: 288 YSLEEGLLETWKWFK 302
SLEEGL ++ ++FK
Sbjct: 296 ISLEEGLRQSIEYFK 310
>gb|AAG09530.1|AF279623_1 (AF279623) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 142 bits (355), Expect = 4e-33
Identities = 109/339 (32%), Positives = 168/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVIDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + + +N VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQNTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
+I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AAITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEAGNSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKSLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALYIVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPLETFESGIRKTVEWYLANT 338
>gb|AAG09537.1|AF279625_1 (AF279625) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 142 bits (355), Expect = 4e-33
Identities = 110/339 (32%), Positives = 168/339 (49%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEGARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEAENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+PL I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALHMVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI +++G+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISREIGWKPLETFESGIRKTVEWYLANT 338
>gb|AAG26471.1|AF285774_11 (AF285774) putative UDP-glucuronic acid epimerase [Bacteroides
fragilis]
Length = 350
Score = 142 bits (355), Expect = 4e-33
Identities = 100/346 (28%), Positives = 170/346 (48%), Gaps = 52/346 (15%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVVV-IDNLYS--------------GKPE--------- 41
++VTG AGFIGSH+ + L + D VV +DN+ S G P+
Sbjct: 3 VLVTGAAGFIGSHVCKRLLQRGDEVVGLDNINSYYDINLKYGRLSSLGVPQSELSWYKFT 62
Query: 42 --NVPEGVKFIEADVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGT 97
NV F+ ++ D +++ + ++ D V + AAQ V S+++P E N+ G
Sbjct: 63 RSNVYPRFSFVRMNLEDRQAMQMLFANGNFDVVINLAAQAGVRYSIENPYAYVESNIDGF 122
Query: 98 INILRALSEGNGK-LIFASSAAVYGEPTSLPIRE-DHPLNPISPYGVSKVSGEHYCKVFY 155
+N+L K L++ASS++VYG +P E D +P+S Y +K S E +
Sbjct: 123 LNVLEGCRHSQVKHLVYASSSSVYGLNGQVPFSEKDGIAHPVSLYAATKKSNELMAHTYS 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
LY +P+ LR+F VYGP + + F + L G P+ +F +G RDF Y+ D+V
Sbjct: 183 HLYNIPSTGLRFFTVYGPWGRPDMSPFL--FADAILHGRPIKVFNNGNMLRDFTYIDDIV 240
Query: 216 EANILVAEK-----------------RRAEGETFNVGTGRETTIIELAMKIIELS-STSS 257
E + VA+ A + +N+G R +++ ++ IE+S +
Sbjct: 241 EGVLRVADSIPEGNQCWDAEVADPSMSCAPYKIYNIGNSRPVKLMDF-IRAIEMSIGREA 299
Query: 258 QILFSKPRPGDIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFK 302
++ +PGD+ ++ AD + +++GF+P SLE G+ +T W+K
Sbjct: 300 DKIYLPMQPGDVYQTYADTSSLSREIGFQPNTSLEAGVKKTISWYK 345
>dbj|BAA19633.1| (AB002668) dTDP-D-glucose-4,6-dehydratase [Actinobacillus
actinomycetemcomitans]
Length = 355
Score = 142 bits (354), Expect = 6e-33
Identities = 107/334 (32%), Positives = 167/334 (49%), Gaps = 40/334 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE--ENDVVVIDNL-YSGKPENVPEGVK------FIEADV 54
K I+VTGGAGFIGS + + E ++ VV +D L Y+G E++ E VK F + D+
Sbjct: 3 KTILVTGGAGFIGSAVVRYIIENTQDSVVNVDKLTYAGNLESL-EAVKNNPRYIFEQVDI 61
Query: 55 RDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLI 112
D +++A I D V H AA+ V+ S+ P E N++GT +L A LI
Sbjct: 62 CDAKALARIFEQHQPDAVMHLAAESHVDRSIDGPATFIETNIVGTYILLEAARAYWSSLI 121
Query: 113 FASSAA----------VYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV 160
A VYG+ T+ E P +P SPY SK S +H + + + Y +
Sbjct: 122 DEKKAGFRFHHISTDEVYGDLDGTNNLFTETTPYSPSSPYSASKASSDHLVRAWLRTYSL 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANIL 220
PT++ N YGP+ +I + + AL G+PL ++G+G+Q RD+++V+D A
Sbjct: 182 PTIVTNCSNNYGPKVFP--EKLIPLIILNALDGKPLPVYGNGQQIRDWLFVEDHARALYK 239
Query: 221 VAEKRRAEGETFNVGTGRETTIIELAMKIIEL------------SSTSSQILFSKPRPGD 268
V + + GET+N+G E I++ I L + I + K RPG
Sbjct: 240 VVTEGKI-GETYNIGGHNEKANIDVVRTICALLEELVPDKPAGVTKYEDLITYVKDRPGH 298
Query: 269 IRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWF 301
R D KI ++LG+KP+ + E G+ +T +W+
Sbjct: 299 DVRYAIDATKISRELGWKPQETFESGIRKTVEWY 332
>sp|O65780|GAE1_CYATE UDP-GLUCOSE 4-EPIMERASE GEPI42 (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|7437271|pir||T10496 UDPglucose
4-epimerase (EC 5.1.3.2) (clone GEPI42) - guar
>gi|3021355|emb|CAA06338.1| (AJ005081) UDP-galactose
4-epimerase [Cyamopsis tetragonoloba]
Length = 354
Score = 142 bits (354), Expect = 6e-33
Identities = 106/338 (31%), Positives = 163/338 (47%), Gaps = 36/338 (10%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENV-----------PEGVKFIEAD 53
I+VTGGAGFIGSH + + LK+ V +IDNLY+ + V + F D
Sbjct: 12 ILVTGGAGFIGSHTVVQLLKQGFHVSIIDNLYNSVIDAVHRVRLLVGPLLSSNLHFHHGD 71
Query: 54 VRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GK 110
+R+ + + S D V H A V ESV +P + N++ TIN+ + +S+ N K
Sbjct: 72 LRNIHDLDILFSKTKFDAVIHFAGLKGVGESVLNPSNYYDNNLVATINLFQVMSKFNCKK 131
Query: 111 LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV-PTVILRYFN 169
L+ +SSA VYG+P +P ED L+ ++PYG SK+ E + + ++LRYFN
Sbjct: 132 LVISSSATVYGQPDQIPCVEDSNLHAMNPYGRSKLFVEEVARDIQRAEAEWRIILLRYFN 191
Query: 170 VYGPRQSSAYA--------GVISIFMERALRGEP-LVIFG------DGKQSRDFVYVKDV 214
G +S ++ + A+ P L I+G DG RD+++V D+
Sbjct: 192 PVGAHESGQIGEDPRGLPNNLMPYIQQVAVARLPELNIYGHDYPTKDGTAIRDYIHVMDL 251
Query: 215 VEANILVAEKRRAEGE----TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIR 270
+ +I K +N+GTGR T+++E+ + S I RPGD
Sbjct: 252 ADGHIAALRKLFTTDNIGCTAYNLGTGRGTSVLEMVAAFEKASGKKIPIKMCPRRPGDAT 311
Query: 271 RSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A EK K+LG+K +Y +EE + WKW + G
Sbjct: 312 AVYASTEKAEKELGWKAKYGVEEMCRDQWKWASNNPWG 349
>gb|AAF67513.1|AF170880_20 (AF170880) NovT [Streptomyces spheroides]
Length = 336
Score = 142 bits (354), Expect = 6e-33
Identities = 97/313 (30%), Positives = 157/313 (49%), Gaps = 19/313 (6%)
Query: 6 IVVTGGAGFIGSHIAEAL-------KEENDVVVIDNL-YSGKPENVP-----EGVKFIEA 52
I+VTGGAGFIGS A V V+D L YSG N+ +F+
Sbjct: 3 ILVTGGAGFIGSEFVRATLRGTLPGSSGTQVTVLDKLTYSGNVLNLAPIADLRNYRFVRG 62
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKL 111
D+ D + + ++V+ D + H AA+ V+ S+ N +GT +L A S G+
Sbjct: 63 DICDQDLVDDVVAGHDAIVHFAAETHVDRSIGSAASFVRTNAMGTQVLLEAASRHRLGRF 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG E+ P+ P +PY +K +G+ +++ +G+ V+ R N Y
Sbjct: 123 VHISTDEVYGSIPEGAWDEESPVAPNAPYAAAKAAGDLLALAWHRTHGLDVVVTRCTNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q +I +F + G+ + ++G+G R +++V D A LV RA GE
Sbjct: 183 GPYQYP--EKLIPLFTTNVMDGQQVPVYGEGHNRRQWLHVSDHCRAIQLVLLGGRA-GEV 239
Query: 232 FNVGTGRETTIIELAMKIIELSSTSSQILFSKP-RPGDIRRSVADIEKIK-KLGFKPRYS 289
+++G G E T +ELA +I++ ++ P RPG R D KI+ +LGF PR +
Sbjct: 240 YHIGGGTELTNLELAEQILKSCGAGWDMVRHVPDRPGHDFRYSLDTTKIRTELGFSPRVA 299
Query: 290 LEEGLLETWKWFK 302
+GL+ET +W++
Sbjct: 300 FADGLVETVEWYR 312
>gb|AAF78439.1|AC018748_18 (AC018748) Contains similarity to dTPD-D-glucose-4,6-dehydratase
from Sphingomonas sp.S88 gb|U51197 and contains a NAD
dependent epimerase/dehydratase PF|01370 domain.
[Arabidopsis thaliana]
>gi|10645356|gb|AAG21476.1|AC024260_19 (AC024260)
dTDP-D-glucose 4,6-dehydratase, putative; 102946-105028
[Arabidopsis thaliana]
Length = 667
Score = 142 bits (354), Expect = 6e-33
Identities = 105/316 (33%), Positives = 158/316 (49%), Gaps = 21/316 (6%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPEGV-----KFIEADV 54
K I++TG AGFI SH+A L + +VV+D L Y +N+ KF++ D+
Sbjct: 9 KNILITGAAGFIASHVANRLIRNYPDYKIVVLDKLDYCSDLKNLDPSFSSPNFKFVKGDI 68
Query: 55 R--DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG--K 110
D + I + D + H AAQ V+ S + + N+ GT +L A +
Sbjct: 69 ASDDLVNYLLITENIDTIMHFAAQTHVDNSFGNSFEFTKNNIYGTHVLLEACKVTGQIRR 128
Query: 111 LIFASSAAVYGEP---TSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRY 167
I S+ VYGE ++ E L P +PY +K E + + YG+P + R
Sbjct: 129 FIHVSTDEVYGETDEDAAVGNHEASQLLPTNPYSATKAGAEMLVMAYGRSYGLPVITTRG 188
Query: 168 FNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRA 227
NVYGP Q +I F+ A+ G+PL I GDG R ++Y +DV EA +V K
Sbjct: 189 NNVYGPNQFPEK--MIPKFILLAMSGKPLPIHGDGSNVRSYLYCEDVAEAFEVVLHKGEI 246
Query: 228 EGETFNVGTGRETTIIELAMKIIEL--SSTSSQILFSKPRPGDIRRSVADIEKIKKLGFK 285
G +NVGT RE +I++A I +L S I F + RP + +R D +K+KKLG++
Sbjct: 247 -GHVYNVGTKRERRVIDVARDICKLFGKDPESSIQFVENRPFNDQRYFLDDQKLKKLGWQ 305
Query: 286 PRYSLEEGLLETWKWF 301
R + E+GL +T W+
Sbjct: 306 ERTNWEDGLKKTMDWY 321
>sp|P37777|RFBB_SHIFL DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|1073703|pir||B55213 rfbB protein -
Shigella flexneri (strain 2a) >gi|294896|gb|AAA53679.1|
(L14842) dTDP-D-glucose 4,6-dehydratase [Shigella
flexneri]
Length = 361
Score = 141 bits (353), Expect = 7e-33
Identities = 108/339 (31%), Positives = 168/339 (48%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVIDNL-YSGKPENVP-----EGVKFIEADVRDY 57
I+VTGGAGFIGS + + ++ VV +D L Y+G E++ E F AD+ D
Sbjct: 3 ILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLADVSDSERYAFEHADICDA 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL----------S 105
+++ I + D V H AA+ V+ S+ P E N++GT +L A
Sbjct: 63 VAMSRIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSALNDEK 122
Query: 106 EGNGKLIFASSAAVYGE---PTSLPIREDHPL-------NPISPYGVSKVSGEHYCKVFY 155
+ + + S+ VYG+ P E PL P SPY SK S +H + +
Sbjct: 123 KKSFRFHHISTDEVYGDLPHPDEANNNEALPLFTETTAYAPSSPYSASKASSDHLVRAWK 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A V + +A GET+N+G E I++ + I +L S QI + RPG
Sbjct: 241 RALYTVVTEGKA-GETYNIGGHNEKKNIDVVLTICDLLDEIVPKEKSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP+ + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPQETFESGIRKTVEWYLANT 338
>gb|AAG09506.1|AF279617_1 (AF279617) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 141 bits (351), Expect = 1e-32
Identities = 110/339 (32%), Positives = 167/339 (48%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEAGNSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKSLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALYIVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKAASYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPLETFESGIRKTVEWYLANT 338
>gb|AAG09526.1|AF279622_1 (AF279622) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 141 bits (351), Expect = 1e-32
Identities = 111/339 (32%), Positives = 168/339 (48%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPEGVK-----FIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + K F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLCDISKSNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEVGNSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKSLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALYIVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPLETFESGIRKTVEWYLANT 338
>gb|AAG09534.1|AF279624_1 (AF279624) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 141 bits (351), Expect = 1e-32
Identities = 110/339 (32%), Positives = 167/339 (48%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
I I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEVGNSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKSLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + +A GET+N+G E +++ I +L +S QI + RPG
Sbjct: 241 RALYIVVTEGKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKANSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPLENFESGIRKTVEWYLANT 338
>dbj|BAA82532.1| (AB030032) dTDP-D-glucose 4,6-dehydratase [Actinobacillus
actinomycetemcomitans]
Length = 355
Score = 140 bits (349), Expect = 2e-32
Identities = 107/334 (32%), Positives = 168/334 (50%), Gaps = 40/334 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE--ENDVVVIDNL-YSGKPENVPEGVK------FIEADV 54
K I+VTGGAGFIGS + + E ++ VV +D L Y+G E++ E VK F + D+
Sbjct: 3 KTILVTGGAGFIGSAVVRYIIENTQDSVVNVDKLTYAGNLESL-EAVKNNPRYTFEQVDI 61
Query: 55 RDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS------E 106
D +++A I D V H AA+ V+ S+ P E N++GT +L A
Sbjct: 62 CDAKALARIFQQHRPDAVMHLAAESHVDRSIDGPAAFIETNIVGTYILLEAARAYWNSLN 121
Query: 107 GNGKLIFA----SSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV 160
K +F S+ VYG+ T+ E P +P SPY SK S +H + + + Y +
Sbjct: 122 DEKKAVFRFHHISTDEVYGDLDGTNNLFIETTPYSPSSPYSASKASSDHLVRAWLRTYSL 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANIL 220
PT++ N YGP +I + + AL G+PL ++G+G+Q RD+++V+D A
Sbjct: 182 PTIVTNCSNNYGPFHFP--EKLIPLIILNALDGKPLPVYGNGQQIRDWLFVEDHARALYK 239
Query: 221 VAEKRRAEGETFNVGTGRETTIIELAMKIIEL------------SSTSSQILFSKPRPGD 268
V + + GET+N+G E I++ I L + I + K RPG
Sbjct: 240 VVAEGKI-GETYNIGGHNEKANIDVVRTICALLEELVPNKPAGVTKYEDLITYVKDRPGH 298
Query: 269 IRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWF 301
R D KI ++LG+KP+ + E G+ +T +W+
Sbjct: 299 DVRYAIDATKISRELGWKPQETFESGIRKTVEWY 332
>pir||T00102 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) - Actinobacillus
actinomycetemcomitans >gi|3132254|dbj|BAA28131.1|
(AB010415) dTDP-D-glucose-4,6-dehydratase
[Actinobacillus actinomycetemcomitans]
Length = 355
Score = 139 bits (347), Expect = 4e-32
Identities = 105/334 (31%), Positives = 166/334 (49%), Gaps = 40/334 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE--ENDVVVIDNL-YSGKPENVPEGVK------FIEADV 54
K I+VTGGAGFIGS + + E ++ VV +D L Y+G E++ E VK F + D+
Sbjct: 3 KTILVTGGAGFIGSAVVRYIIENTQDSVVNVDKLTYAGNLESL-ETVKNNPRYIFEQVDI 61
Query: 55 RDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-------- 104
D +++A I D V H AA+ V+ S+ P E N++GT +L A
Sbjct: 62 CDAKALARIFEQHQPDVVMHLAAESHVDRSIDGPAAFIETNIVGTYILLEAARAYWSSLN 121
Query: 105 --SEGNGKLIFASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ + S+ VYG+ T E P +P SPY SK S +H + + + Y +
Sbjct: 122 DEKKAGFRFHHISTDEVYGDLDGTKNLFTETTPYSPSSPYSASKASSDHLVRAWLRTYSL 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANIL 220
PT++ N YGP +I + + AL G+PL ++G+G+Q RD+++V+D A
Sbjct: 182 PTIVTNCSNNYGPFHFP--EKLIPLIILNALDGKPLPVYGNGQQIRDWLFVEDHARALYK 239
Query: 221 VAEKRRAEGETFNVGTGRETTIIELAMKIIEL------------SSTSSQILFSKPRPGD 268
V + + GET+N+G E I++ I L + I + K RPG
Sbjct: 240 VVTEGKI-GETYNIGGHNEKANIDVVRTICALLEELVPNKPAGVTKYEDLITYVKDRPGH 298
Query: 269 IRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWF 301
R D KI ++LG+KP+ + E G+ +T +W+
Sbjct: 299 DVRYAIDATKISRELGWKPQETFESGIRKTVEWY 332
>sp|Q9T0A7|GAE3_ARATH PROBABLE UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|7437229|pir||T08911 UDPglucose
4-epimerase (EC 5.1.3.2) T32A16.90 - Arabidopsis
thaliana >gi|4972096|emb|CAB43892.1| (AL078468)
UDPglucose 4-epimerase-like protein [Arabidopsis
thaliana] >gi|7269241|emb|CAB81310.1| (AL161560)
UDPglucose 4-epimerase-like protein [Arabidopsis
thaliana]
Length = 350
Score = 139 bits (347), Expect = 4e-32
Identities = 99/339 (29%), Positives = 165/339 (48%), Gaps = 36/339 (10%)
Query: 4 KLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVPEGVK----------FIEA 52
K ++VTGGAG+IGSH + + L+ VV+DN + ++ K F +
Sbjct: 3 KSVLVTGGAGYIGSHTVLQLLEGGYSAVVVDNYDNSSAASLQRVKKLAGENGNRLSFHQV 62
Query: 53 DVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNG 109
D+RD ++ +I S D V H A +V ESV+ P+ N++GT+ +L +++ G
Sbjct: 63 DLRDRPALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNIVGTVTLLEVMAQYGCK 122
Query: 110 KLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV-PTVILRYF 168
L+F+SSA VYG P +P E+ P++ +PYG +K+ E C+ ++ ++LRYF
Sbjct: 123 NLVFSSSATVYGWPKEVPCTEESPISATNPYGRTKLFIEEICRDVHRSDSEWKIILLRYF 182
Query: 169 NVYGPRQSSAYAGVISIFMERAL----------RGEPLVIFG------DGKQSRDFVYVK 212
N G S Y G + + L R L +FG DG RD+++V
Sbjct: 183 NPVG-AHPSGYIGEDPLGVPNNLMPYVQQVAVGRRPHLTVFGTDYKTKDGTGVRDYIHVM 241
Query: 213 DVVEANILVAEK---RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
D+ + +I K + E +N+GTG T+++E+ + S ++ + RPGD
Sbjct: 242 DLADGHIAALRKLDDLKISCEVYNLGTGNGTSVLEMVAAFEKASGKKIPLVMAGRRPGDA 301
Query: 270 RRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A EK ++L +K + +EE + W W + G
Sbjct: 302 EVVYASTEKAERELNWKAKNGIEEMCRDLWNWASNNPYG 340
>dbj|BAA94402.1| (AB041266) dTDP-D-glucose 4,6-dehydratase [Actinobacillus
actinomycetemcomitans]
Length = 355
Score = 139 bits (346), Expect = 5e-32
Identities = 104/334 (31%), Positives = 167/334 (49%), Gaps = 40/334 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE--ENDVVVIDNL-YSGKPENVPEGVK------FIEADV 54
K I++TGGAGFIGS + + E ++ VV +D L Y+G E++ E VK F + D+
Sbjct: 3 KNILITGGAGFIGSAVVRYIIENTQDSVVNVDKLTYAGNLESL-EAVKNNPRYIFEQVDI 61
Query: 55 RDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-------- 104
D +++A I D V H AA+ V+ S+ P E N++GT +L A
Sbjct: 62 CDAKALARIFEQHQPDAVMHLAAESHVDRSIDGPATFIETNIVGTYILLEAARAYWSSLN 121
Query: 105 --SEGNGKLIFASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ + S+ VYG+ T+ E P +P SPY SK S +H + + + Y +
Sbjct: 122 DEKKAGFRFHHISTDEVYGDLDGTNNLFTETTPYSPSSPYSASKASSDHLVRAWLRTYSL 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANIL 220
PT++ N YGP +I + + AL G+PL ++G+G+Q RD+++V+D A
Sbjct: 182 PTIVTNCSNNYGPFHFP--EKLIPLIILNALDGKPLPVYGNGQQIRDWLFVEDHARALYK 239
Query: 221 VAEKRRAEGETFNVGTGRETTIIELAMKIIEL------------SSTSSQILFSKPRPGD 268
V + + GET+N+G E I++ I L + I + K RPG
Sbjct: 240 VVTEGKI-GETYNIGGHNEKANIDVVRTICALLEELVPDKPAGVTKYEDLITYVKDRPGH 298
Query: 269 IRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWF 301
R D KI ++LG+KP+ + E G+ +T +W+
Sbjct: 299 DVRYAIDATKISRELGWKPQETFESGIRKTVEWY 332
>gb|AAG09522.1|AF279621_1 (AF279621) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 139 bits (346), Expect = 5e-32
Identities = 111/339 (32%), Positives = 165/339 (47%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I++TGGAGFIGS + +K D VV ID L Y+G E++ + F AD+ D
Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-------ALSE-- 106
IA I D V H AA+ V+ S+ P E N++GT +L AL E
Sbjct: 63 AEIARIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYILLEVARKYWSALGEDK 122
Query: 107 -GNGKLIFASSAAVYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG+ +LP+ E P SPY SK S +H + +
Sbjct: 123 KNSFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWR 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKSLPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A +V + GET+N+G E +E+ I +L S QI + RPG
Sbjct: 241 RALHMVVTQGEV-GETYNIGGHNEKKNLEVVHTICDLLDEIVPKEGSYRDQITYVGDRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPLETFESGIRKTVEWYLANT 338
>sp|P55293|RBB2_ECOLI DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|7437235|pir||S78542 dTDPglucose
4,6-dehydratase (EC 4.2.1.46) - Escherichia coli (strain
VW187) >gi|799232|gb|AAC63612.1| (AF125322) RmlB
[Escherichia coli]
Length = 361
Score = 138 bits (345), Expect = 6e-32
Identities = 107/339 (31%), Positives = 163/339 (47%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVIDNL-YSGKPENVPE-----GVKFIEADVRDY 57
I+VTGGAGFIGS + + ++ VV +D L Y+G E++ E F AD+ D
Sbjct: 3 ILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLAEISDSERYSFENADICDA 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL----------S 105
E D V H AA+ V+ S+ P E N++GT +L A
Sbjct: 63 EGDGLYFGQHQLDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSGLDDEK 122
Query: 106 EGNGKLIFASSAAVYGE-PTSLPIREDHPLN---------PISPYGVSKVSGEHYCKVFY 155
+ N + S+ VYG+ P + + L P SPY SK S +H + +
Sbjct: 123 KKNFRFHHISTDEVYGDLPHPDEVNSNETLQLFTETTAYAPSSPYSASKASSDHLVRAWK 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVSNCSNNYGPYHFP--EKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A V + +A GET+N+G E I++ I +L S QI + RPG
Sbjct: 241 RALYTVVTEGKA-GETYNIGGHNEKKNIDVVFTICDLLDEIVPKEKSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP+ + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPQETFESGIRKTVEWYLANT 338
>sp|Q45291|GALE_BRELA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|2144276|pir||JC5168 UDPglucose
4-epimerase (EC 5.1.3.2) - Corynebacterium glutamicum
>gi|1161517|emb|CAA89986.1| (Z49823) UDP-galactose
4-epimease [Corynebacterium glutamicum]
Length = 329
Score = 138 bits (344), Expect = 8e-32
Identities = 99/318 (31%), Positives = 160/318 (50%), Gaps = 17/318 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV 64
++VTGGAG++GS A L E +DV +IDN +G E VP + IE DV D +
Sbjct: 3 LLVTGGAGYVGSVRAAVLLEHGHDVTIIDNFSTGNREAVPADARLIEGDVNDVVEEVLLE 62
Query: 65 SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGNGKLIFASSAAVYGEP 123
+ V H AA+ V ESV+ P NV+ + +L A+ + G L+F+S+AA YGEP
Sbjct: 63 GGFEGVVHFAARSLVGESVEKPNEYWHDNVVTALTLLDAMRAHGVNNLVFSSTAATYGEP 122
Query: 124 TSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP-----RQSSA 178
+PI ED P P + YG +K+S ++ + +G+ LRYFNV G
Sbjct: 123 DVVPITEDMPTQPTNAYGATKLSIDYAITSYAAAFGLAATSLRYFNVAGAYGNIGENREV 182
Query: 179 YAGVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEANILVAEKRRA-EGE 230
+I + ++ A E + +FG DG RD++++ D+ +A++L E A +
Sbjct: 183 ETHLIPLVLQVATGHREKIFMFGDDWPTPDGTAVRDYIHILDLAKAHVLALESNEAGKHR 242
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYS 289
FN+G+G ++ ++ E++ + R GD +A EK K +LG+ P ++
Sbjct: 243 IFNLGSGDGYSVKQVVEMCREVTGHPIPAEVAPRRAGDPATLIASSEKAKQELGWTPEHT 302
Query: 290 LEEGLLETWKWFKSRTLG 307
++E W + LG
Sbjct: 303 DLRTIVED-AWAFTSALG 319
>gb|AAD30579.1|AC007260_10 (AC007260) Similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis
thaliana]
Length = 669
Score = 138 bits (344), Expect = 8e-32
Identities = 101/316 (31%), Positives = 153/316 (47%), Gaps = 21/316 (6%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVID------NLYSGKPENVPEGVKFIEADV 54
K I++TG AGFI SH+A L + +VV+D NL + P KF++ D+
Sbjct: 7 KNILITGAAGFIASHVANRLIRSYPDYKIVVLDKLDYCSNLKNLNPSKHSPNFKFVKGDI 66
Query: 55 RDYESIAE--IVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG--K 110
+ + I D + H AAQ V+ S + + N+ GT +L A +
Sbjct: 67 ASADLVNHLLITEGIDTIMHFAAQTHVDNSFGNSFEFTKNNIYGTHVLLEACKVTGQIRR 126
Query: 111 LIFASSAAVYGEPTSLPIREDHP---LNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRY 167
I S+ VYGE + +H L P +PY +K E + + YG+P + R
Sbjct: 127 FIHVSTDEVYGETDEDALVGNHEASQLLPTNPYSATKAGAEMLVMAYGRSYGLPVITTRG 186
Query: 168 FNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRA 227
NVYGP Q +I F+ A+RG+ L I GDG R ++Y +DV EA +V K
Sbjct: 187 NNVYGPNQFP--EKLIPKFILLAMRGQVLPIHGDGSNVRSYLYCEDVAEAFEVVLHKGEV 244
Query: 228 EGETFNVGTGRETTIIELAMKIIEL--SSTSSQILFSKPRPGDIRRSVADIEKIKKLGFK 285
G +N+GT +E + ++A I +L + I F RP + +R D +K+KKLG+
Sbjct: 245 -GHVYNIGTKKERRVNDVAKDICKLFNMDPEANIKFVDNRPFNDQRYFLDDQKLKKLGWS 303
Query: 286 PRYSLEEGLLETWKWF 301
R + EEGL +T W+
Sbjct: 304 ERTTWEEGLKKTMDWY 319
>pir||T10588 UDPglucose 4-epimerase homolog F9F13.110 - Arabidopsis thaliana
>gi|5262169|emb|CAB45812.1| (AL080253) UDP-glucose
4-epimerase-like protein [Arabidopsis thaliana]
>gi|7268842|emb|CAB79046.1| (AL161553) UDP-glucose
4-epimerase-like protein [Arabidopsis thaliana]
Length = 379
Score = 138 bits (344), Expect = 8e-32
Identities = 114/339 (33%), Positives = 164/339 (47%), Gaps = 40/339 (11%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENV---------PEGVKFIEADVR 55
++VTGGAG+IGSH A LK+ V ++DNL G V P ++FI AD+
Sbjct: 40 VLVTGGAGYIGSHAALRLLKDSYRVTIVDNLSRGNLGAVKVLQGLFPEPGRLQFIYADLG 99
Query: 56 DYESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLI 112
D +++ +I S + D V H AA V ES DP+ T+ +L A++ KLI
Sbjct: 100 DAKAVDKIFSENAFDAVMHFAAVAYVGESTLDPLKYYHNITSNTLVVLEAVARHKVKKLI 159
Query: 113 FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
++S+ A YGEP +PI E P PI+PYG +K E F + + +ILRYFNV G
Sbjct: 160 YSSTCATYGEPDKMPIVEVTPQVPINPYGKAKKMAEDMILDFSKNSDMAVMILRYFNVIG 219
Query: 173 ----------PRQSSAYAGVISIFMERALRGEPLVI-----------FGDGKQSRDFVYV 211
P+ G IS A RG VI GDG RD++ V
Sbjct: 220 SDPEGRLGEAPKPELREHGRISGACFDAARG---VIPGLQVKGTDYKTGDGTCVRDYIDV 276
Query: 212 KDVVEANILVAEKRRAEG-ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIR 270
D+V+A++ EK + +NVGTG+ ++ E + + ++ F RPGD
Sbjct: 277 TDLVDAHVKALEKAKPRNVGIYNVGTGKGRSVKEFVEACKKATGVDIKVDFLPRRPGDYA 336
Query: 271 RSVADIEKI-KKLGFKPRY-SLEEGLLETWKWFKSRTLG 307
+D KI + L + RY +L+E L WKW K+ G
Sbjct: 337 EVYSDPAKILRDLNWSARYTNLQESLEVAWKWQKTHPHG 375
>gb|AAD50491.1|AF172324_9 (AF172324) UDP-Glc-4-epimerase GalE [Escherichia coli]
Length = 337
Score = 138 bits (343), Expect = 1e-31
Identities = 104/336 (30%), Positives = 171/336 (49%), Gaps = 38/336 (11%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENVPEGVK--------FIEADVRD 56
+++TGG G+IG HIA E L++ +DVV+ DNL S V E +K FI D+R
Sbjct: 3 VLLTGGLGYIGCHIAVELLQQGHDVVIFDNL-SNSHLTVLERIKAITQKKVVFIRGDLRS 61
Query: 57 YESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIF 113
I + S+ + V H AA SV ESV+ P+ NV+G++N+++A+S N K LIF
Sbjct: 62 LSDIRKTFESSQIEAVIHLAALKSVSESVRHPLEYYINNVVGSLNLIQAMSHANIKRLIF 121
Query: 114 ASSAAVYGEPTSLPIREDHPLNPI-SPYGVSKVSGEHYCKVFYQLYGV----PTVILRYF 168
+SSA VYG+P LPI E + + +PYG +K+ E K+ + LRYF
Sbjct: 122 SSSATVYGQPEHLPITEQASVGKVTNPYGQTKLIIE---KILADICLADPEWQITSLRYF 178
Query: 169 NVYGPRQSSAYA--------GVISIFMERALRGEP-LVIFG------DGKQSRDFVYVKD 213
N G S ++ + A+R P I G DG RD+++V+D
Sbjct: 179 NPIGAHPSGMIGEDPRGMPNNILPYITQVAIRRRPYFTILGDDYPTKDGTGVRDYIHVQD 238
Query: 214 VVEANI-LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRS 272
+ +I + + + +N+GTG+ +++++ E+++ + K RPGDI
Sbjct: 239 LALGHIAALMNAKNKSYQVYNLGTGKGYSVLDIINSFKEINNIDIPFIIEKRRPGDIAEC 298
Query: 273 VADIEKIKK-LGFKPRYSLEEGLLETWKWFKSRTLG 307
+ E K+ LG++ ++ L++ L ++W W + G
Sbjct: 299 WSSPELAKRELGWQAKFELKDMLRDSWNWQQKNPFG 334
>sp|P39630|SPSJ_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROTEIN SPSJ
>gi|629079|pir||S39727 dTDPglucose 4,6-dehydratase (EC
4.2.1.46) spsJ - Bacillus subtilis
>gi|413996|emb|CAA51628.1| (X73124) ipa-72d [Bacillus
subtilis] >gi|2636318|emb|CAB15809.1| (Z99123) alternate
gene name: ipa-72d [Bacillus subtilis]
Length = 315
Score = 137 bits (342), Expect = 1e-31
Identities = 98/311 (31%), Positives = 154/311 (49%), Gaps = 16/311 (5%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEND--VVVIDNL-YSGKPENVPE-----GVKFIEADVR 55
K ++TGGAGFIG + + E D + V+D L Y+ PE + + +F++ D+
Sbjct: 3 KSYLITGGAGFIGLTFTKLMLRETDARITVLDKLTYASHPEEMEKLKQNSRFRFVKGDIS 62
Query: 56 DYESIAEIVSSA-DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIF 113
E I D V H AA+ V+ S+ NV+GT + A+ +G K LI
Sbjct: 63 VQEDIDRAFDETYDGVIHFAAESHVDRSISQAEPFITTNVMGTYRLAEAVLKGKAKKLIH 122
Query: 114 ASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
S+ VYG+ E PL+P +PY SK S + + + + +P +I R N Y
Sbjct: 123 ISTDEVYGDLKADDPAFTETTPLSPNNPYSASKASSDLLVLSYVKTHKLPAIITRCSNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q S +I + A +G P+ ++GDG Q RD+++ +D A L+ EK +GE
Sbjct: 183 GPYQHS--EKMIPTIIRHAKQGLPVPLYGDGLQIRDWLFAEDHCRAIKLILEK-GTDGEV 239
Query: 232 FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSL 290
+N+G G E T ELA I++ + R G RR + K+K +LG++ +
Sbjct: 240 YNIGGGNERTNKELASVILKHLGCEELFAHVEDRKGHDRRYAINASKLKNELGWRQEVTF 299
Query: 291 EEGLLETWKWF 301
EEG+ T +W+
Sbjct: 300 EEGIARTIQWY 310
>sp|P13226|GALE_STRLI UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE)
Length = 329
Score = 137 bits (342), Expect = 1e-31
Identities = 101/319 (31%), Positives = 162/319 (50%), Gaps = 18/319 (5%)
Query: 7 VVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIVS 65
+VTGGAG++GS +A+ L E N+VVV+ NL +G VP G F D+RD + + ++
Sbjct: 6 LVTGGAGYVGSVVAQHLVEAGNEVVVLHNLSTGFRAGVPAGASFYRGDIRDQDFMRKVFR 65
Query: 66 ---SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGNGKLIFASSAAVYG 121
S D V H AA V ESV P + NV GT+ +L A+ G +L+F+S+AA YG
Sbjct: 66 GRLSFDGVLHFAAFSQVGESVVKPEKYWDNNVGGTMALLEAMRGAGVRRLVFSSTAATYG 125
Query: 122 EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQS----- 176
EP +PI E P P +PYG SK++ +H +G+ V + YFNV G +
Sbjct: 126 EPEQVPIVESAPTRPTNPYGASKLAVDHMITGEAAAHGLGAVSVPYFNVAGANRGVRLVH 185
Query: 177 SAYAGVISIFMERAL-RGEPLVIFGDGKQS-----RDFVYVKDVVEANILVAEKRRA-EG 229
+ +I + ++ A R E + ++GD + RD+++V D+ EA++L +R E
Sbjct: 186 DPESHLIPLVLQVAQGRREAISVYGDDYPTPDTCVRDYIHVADLAEAHLLAVRRRPGNEH 245
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRY 288
N+G G ++ E+ + ++ + + R D VA + KLG+ P
Sbjct: 246 LICNLGNGNGFSVREVVETVRRVTGHPIPEIMAPRRGRDPAVLVASAGTAREKLGWNPSR 305
Query: 289 SLEEGLLETWKWFKSRTLG 307
+ + + W+W S G
Sbjct: 306 ADLAIVSDAWEWHSSHPKG 324
>pir||S41534 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) - Shigella flexneri
>gi|581659|emb|CAA50767.1| (X71970) rfbB [Shigella
flexneri]
Length = 361
Score = 137 bits (341), Expect = 2e-31
Identities = 107/339 (31%), Positives = 166/339 (48%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAEAL--KEENDVVVIDNL-YSGKPENVP-----EGVKFIEADVRDY 57
I VTGGAGFIGS + + ++ VV +D L Y+G E++ E F AD+ D
Sbjct: 3 IPVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLADVSDSERYAFEHADICDA 62
Query: 58 ESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL----------S 105
+++ I +A V H AA+ V+ S+ P E N++GT +L A
Sbjct: 63 VAMSRIFRTAPARRVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSALNDEK 122
Query: 106 EGNGKLIFASSAAVYGE---PTSLPIREDHPL-------NPISPYGVSKVSGEHYCKVFY 155
+ + + S+ VYG+ P E PL SPY SK S +H + +
Sbjct: 123 KKSFRFHHISTDEVYGDLPHPDEANNNETLPLFTETTTKRQNSPYSASKASNDHLVRAWK 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG+PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGLPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A V + +A GET+N+G E I++ + I +L S QI + RPG
Sbjct: 241 RALYTVVTEGKA-GETYNIGGHNEKKNIDVVLTICDLLDEIVPKEKSYREQITYVADRPG 299
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
RR D +KI ++LG+KP+ + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDADKISRELGWKPQETFESGIRKTVEWYLANT 338
>pir||T15892 hypothetical protein D2096.4 - Caenorhabditis elegans
>gi|1065948|gb|AAA81490.1| (U40800) similar to thymidine
diphosphoglucose 4,6-dehydratase [Caenorhabditis
elegans]
Length = 467
Score = 136 bits (340), Expect = 2e-31
Identities = 88/308 (28%), Positives = 164/308 (52%), Gaps = 10/308 (3%)
Query: 4 KLIVVTGGAGFIGSHIAEALK-EENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAE 62
K I++TGGAGF+GSH+ + L + ++V+ +DN ++G+ +NV + ++ ++ +
Sbjct: 137 KRILITGGAGFVGSHLVDKLMLDGHEVIALDNYFTGRKKNVEHWIGHPNFEMVHHDVVNP 196
Query: 63 IVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYGE 122
D ++H A+ S + +PV T + N +GTIN+L ++ AS++ VYG+
Sbjct: 197 YFVEVDQIYHLASPASPPHYMYNPVKTIKTNTLGTINMLGLAKRVKATVLLASTSEVYGD 256
Query: 123 PTSLPIREDH--PLNPISP---YGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS 177
P P E + +N I P Y K E + + + I R FN +GPR
Sbjct: 257 PEVHPQPETYWGHVNTIGPRACYDEGKRVAESLMVAYNKQENIKIRIARIFNTFGPRMHM 316
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
V+S F+ +AL+ +P+ I+G+G Q+R F YV D+V+ I + + N+G
Sbjct: 317 NDGRVVSNFIIQALQDKPITIYGNGTQTRSFQYVTDLVDGLIKLMNSNYS--LPVNIGNP 374
Query: 238 RETTIIELAMKIIEL-SSTSSQILFSKPRPGDIRRSVADIEK-IKKLGFKPRYSLEEGLL 295
E TI + A I +L ++S+I+ + + D ++ DI + +++ + P+ +++GLL
Sbjct: 375 EEHTIGQFATIIRDLVPGSTSEIVNLESQQDDPQQRRPDIRRAAEQISWAPQVHMKDGLL 434
Query: 296 ETWKWFKS 303
+T +F++
Sbjct: 435 KTVDYFRA 442
>gb|AAB48319.1| (U29691) CDP-tyvelose epimerase [Yersinia pseudotuberculosis]
Length = 338
Score = 136 bits (338), Expect = 4e-31
Identities = 100/340 (29%), Positives = 173/340 (50%), Gaps = 47/340 (13%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVVIDNLYS-GKPENVP-----EGVKFIEADVRDYE 58
+++TGG GF+GS++A A+K +V+V DNL G +N+ G ++ D+R+
Sbjct: 3 LLITGGCGFLGSNLASHAIKSGMEVIVFDNLSRYGSSDNLKWLQSIGGFTYVHGDIRNRN 62
Query: 59 SIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK--LIFA 114
I ++ D +FH A Q+++ S+ +P EVNV GT N+L A+ N + +I++
Sbjct: 63 DITRLIQKFKPDSIFHLAGQVAMTTSIDNPQMDFEVNVGGTFNLLEAIRLFNPECGIIYS 122
Query: 115 SSAAVYGEPTSLPIR----------------EDHPLNPISPYGVSKVSGEHYCKVFYQLY 158
S+ VYG+ R E L SPYG SK + + Y + ++Y
Sbjct: 123 STNKVYGDLEQFTYRETDTRYECIEMPDGFDESTQLTFHSPYGCSKGAADQYMLDYARIY 182
Query: 159 GVPTVILRYFNVYGPRQSSAY-AGVISIFMERALR-----GEPLVIFGDGKQSRDFVYVK 212
G+ TV+ R+ ++YG RQ S Y G + F ++A+ P I G+GKQ RD ++ +
Sbjct: 183 GLKTVVFRHSSMYGGRQFSTYDQGWVGWFCQKAIEASRGVNSPFAISGNGKQVRDVLHAE 242
Query: 213 DVVEANI-LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSS-----TSSQILFSK--P 264
D++ ++ R +G FN+G IE ++ ++EL S T +++ +++
Sbjct: 243 DIISLYFSTLSNLERVKGNAFNIG-----GTIEHSLSLLELFSLLEKYTETELKYTRIPV 297
Query: 265 RPGDIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKS 303
R D + VA+I KI + G+ P+ S E G+ W ++
Sbjct: 298 RESDQKVFVANINKISESTGWIPKVSSESGIKIMLDWVET 337
>dbj|BAB07428.1| (AP001519) nucleotide sugar epimerase (biosynthesis of
lipopolysaccharide O antigen) [Bacillus halodurans]
Length = 343
Score = 136 bits (338), Expect = 4e-31
Identities = 98/333 (29%), Positives = 168/333 (50%), Gaps = 39/333 (11%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVVV-IDNL---YSGKPENVP-------EGVKFIEADV 54
I+VTG AGFIG ++A+ L EE VV IDNL Y + +N +F + D+
Sbjct: 3 ILVTGAAGFIGMYVAKRLLEEGHFVVGIDNLNDYYDPQLKNDRLLQLRELGNFEFHKMDL 62
Query: 55 RDYESIAEIVSSAD--YVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-L 111
+ + + ++ + +V + AAQ V S+K+P + N++G N+L + E N K L
Sbjct: 63 TERDRLRQLFLDKEITHVINLAAQAGVRYSLKNPHAYIDSNLVGFTNLLESCRELNVKHL 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLN-PISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
I+ASS++VYG +P +N P+S Y +K + E + LY +PT LR+F V
Sbjct: 123 IYASSSSVYGANRKMPFATSDEVNHPVSLYAATKKANELLAHSYSHLYHIPTTGLRFFTV 182
Query: 171 YGP--RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEK---- 224
YGP R AY F + + G+ + +F G+ RDF Y+ D+V+ + + E+
Sbjct: 183 YGPWGRPDMAYFS----FTKNIVEGQTIKVFNHGEMMRDFTYIDDIVDGVVALLEQPPQA 238
Query: 225 -------------RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRR 271
A + +N+G + +++ + + ++ F +PGD++
Sbjct: 239 DPNWDFEHPMASSSYAPYKIYNIGNNQPVKLMDFIETLEKHLGIEAKKEFLPMQPGDVQA 298
Query: 272 SVADIEKIKK-LGFKPRYSLEEGLLETWKWFKS 303
+ ADI+ +++ GF P S++EGL + WFK+
Sbjct: 299 TYADIDDLQQATGFTPSTSIDEGLKKFVDWFKT 331
>sp|Q43070|GAE1_PEA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|7437228|pir||T06526 UDPglucose
4-epimerase (EC 5.1.3.2) - garden pea
>gi|1173555|gb|AAA86532.1| (U31544)
UDP-galactose-4-epimerase [Pisum sativum]
Length = 350
Score = 135 bits (336), Expect = 7e-31
Identities = 98/338 (28%), Positives = 168/338 (48%), Gaps = 36/338 (10%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPE-----------NVPEGVKFIEAD 53
I+VTG AGFIG+H + + L +V +IDN + E N+ + ++F D
Sbjct: 8 ILVTGSAGFIGTHTVVQLLNNGFNVSIIDNFDNSVMEAVERVREVVGSNLSQNLEFTLGD 67
Query: 54 VRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GK 110
+R+ + + ++ S + D V H A +V ESV++P + N++GTIN+ +++ N K
Sbjct: 68 LRNKDDLEKLFSKSKFDAVIHFAGLKAVGESVENPRRYFDNNLVGTINLYEVMAKHNCKK 127
Query: 111 LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV-PTVILRYFN 169
++F+SSA VYG+P +P ED L ++PYG +K+ E + + V+LRYFN
Sbjct: 128 MVFSSSATVYGQPEKIPCVEDFKLQAMNPYGRTKLFLEEIARDIQKAEPEWRIVLLRYFN 187
Query: 170 VYGPRQSSAYA----GV---ISIFMERALRGE--PLVIFG------DGKQSRDFVYVKDV 214
G +S G+ + ++++ G L ++G DG RD+++V D+
Sbjct: 188 PVGAHESGKLGEDPRGIPNNLMPYIQQVAVGRLPELNVYGHDYPTRDGSAIRDYIHVMDL 247
Query: 215 VEANILVAEK----RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIR 270
+ +I K +N+GTGR ++++E+ + S + RPGD
Sbjct: 248 ADGHIAALRKLFTSENIGCTAYNLGTGRGSSVLEMVAAFEKASGKKIALKLCPRRPGDAT 307
Query: 271 RSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A K K+LG+K +Y +EE + W W K+ G
Sbjct: 308 EVYASTAKAEKELGWKAKYGVEEMCRDQWNWAKNNPWG 345
>gb|AAG21514.1|AC066689_8 (AC066689) UDP-galactose 4-epimerase, putative; 6572-4109
[Arabidopsis thaliana]
Length = 348
Score = 135 bits (336), Expect = 7e-31
Identities = 102/338 (30%), Positives = 166/338 (48%), Gaps = 38/338 (11%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP----------EGVKFIEADV 54
I+VTGGAG+IGSH + + L + VVIDNL + ++ + + + D+
Sbjct: 5 ILVTGGAGYIGSHTVLQLLLGGYNTVVIDNLDNSSLVSIQRVKDLAGDHGQNLTVHQVDL 64
Query: 55 RDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS-EGNGKL 111
RD ++ ++ S D V H A +V ESV P+ N+I TI +L ++ G KL
Sbjct: 65 RDKPALEKVFSETKFDAVMHFAGLKAVGESVAKPLLYYNNNLIATITLLEVMAAHGCKKL 124
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVP---TVILRYF 168
+F+SSA VYG P +P E+ PL+ +SPYG +K+ E C+ + G P ++LRYF
Sbjct: 125 VFSSSATVYGWPKEVPCTEESPLSGMSPYGRTKLFIEDICRDVQR--GDPEWRIIMLRYF 182
Query: 169 NVYGPRQSSAYA-------GVISIFMERALRGE--PLVIFG------DGKQSRDFVYVKD 213
N G S + ++++ + G L I+G DG RD+++V D
Sbjct: 183 NPVGAHPSGRIGEDPCGTPNNLMPYVQQVVVGRLPNLKIYGTDYTTKDGTGVRDYIHVVD 242
Query: 214 VVEANILVAEK---RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIR 270
+ + +I +K E +N+GTG+ TT++E+ + S ++ RPGD
Sbjct: 243 LADGHICALQKLDDTEIGCEVYNLGTGKGTTVLEMVDAFEKASGMKIPLVKVGRRPGDAE 302
Query: 271 RSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A EK ++L +K + +EE + W W + G
Sbjct: 303 TVYASTEKAERELNWKANFGIEEMCRDQWNWASNNPFG 340
>gb|AAC18831.1| (AF059755) nucleotide sugar epimerase [Vibrio vulnificus]
Length = 334
Score = 134 bits (335), Expect = 9e-31
Identities = 98/328 (29%), Positives = 159/328 (47%), Gaps = 34/328 (10%)
Query: 7 VVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEG---------VKFIEADVRD 56
+VTG AGFIGS AE L ++VV IDNL N+ KF+ D+ D
Sbjct: 4 LVTGAAGFIGSATAEKLNAAGHEVVGIDNLNDYYDVNLKHARLARIENPLFKFVSVDISD 63
Query: 57 YESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIF 113
++ ++ ++ D V H AAQ V S+++P + N++G +NIL + L++
Sbjct: 64 RGAMEQLFATEKFDRVIHLAAQAGVRYSLENPHAYADSNLVGHLNILEGCRQNKVSHLVY 123
Query: 114 ASSAAVYGEPTSLPIR-EDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
ASS++VYG +P D +P+S Y +K S E + LY +PT LR+F VYG
Sbjct: 124 ASSSSVYGLNAKVPFSTSDSVDHPVSLYAPTKKSNELMAHSYSHLYDIPTTGLRFFTVYG 183
Query: 173 PRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET- 231
A I F ++ L G+ + I +G RDF +V D+VE + +A+ E+
Sbjct: 184 SWGRPDMAPFI--FTKKILDGDAIDINNNGDMWRDFTHVDDIVEGVVRIADVIPTRNESW 241
Query: 232 ----------------FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+N+G G +++ I ++ F + +PGD+ ++ AD
Sbjct: 242 TVEAGTPATSSAPYSVYNIGHGSPINLMDFVKAIENELGIEAKKNFREMQPGDVYQTYAD 301
Query: 276 IEKI-KKLGFKPRYSLEEGLLETWKWFK 302
E + G+KPR +++EG+ E W+K
Sbjct: 302 TEDLFTATGYKPRVTVKEGVAEFVSWYK 329
>gb|AAB82632.1| (AC002387) putative nucleotide sugar epimerase [Arabidopsis
thaliana]
Length = 437
Score = 134 bits (334), Expect = 1e-30
Identities = 101/333 (30%), Positives = 166/333 (49%), Gaps = 40/333 (12%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPE---------GVKFIEADVR 55
++VTG AGF+G+H++ ALK D V+ +DN ++ G+ +E D+
Sbjct: 99 VLVTGAAGFVGTHVSAALKRRGDGVIGLDNFNDYYDPSLKRARRALLERSGIFIVEGDIN 158
Query: 56 DYESIAEI--VSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK--L 111
D E + ++ + S +V H AAQ V ++++P N+ G +N+L N + +
Sbjct: 159 DVELLRKLFKIVSFTHVMHLAAQAGVRYAMENPSSYVHSNIAGFVNLLEICKSVNPQPAI 218
Query: 112 IFASSAAVYGEPTSLPIRE-DHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
++ASS++VYG T +P E D P S Y +K +GE + +YG+ LR+F V
Sbjct: 219 VWASSSSVYGLNTKVPFSEKDKTDQPASLYAATKKAGEEIAHTYNHIYGLSLTGLRFFTV 278
Query: 171 YGP--RQSSAYAGVISIFMERALRGEPLVIF---GDGKQSRDFVYVKDVVE---ANILVA 222
YGP R AY F + L+G+ + IF G +RDF Y+ D+V+ A + A
Sbjct: 279 YGPWGRPDMAY----FFFTKDILKGKSISIFESANHGTVARDFTYIDDIVKGCLAALDTA 334
Query: 223 EKRRAEG---------ETFNVGTGRETTIIELAMKIIE--LSSTSSQILFSKPRPGDIRR 271
EK G FN+G + +L ++I+E L + + L PR GD+
Sbjct: 335 EKSTGSGGKKRGPAQLRVFNLGNTSPVPVSDL-VRILERQLKVKAKKNLIKMPRNGDVPF 393
Query: 272 SVADIEKI-KKLGFKPRYSLEEGLLETWKWFKS 303
+ A+I ++LG+KP L+ GL + +W+ S
Sbjct: 394 THANISLAQRELGYKPTTDLQTGLKKFVRWYLS 426
>gb|AAF33465.1| (AF233324) 89% identity with E. coli dTDP-D-glucose-4,6-dehydratase
(RFFG) (SP:P27830); contains similarity to Pfam family
PF01370 (NAD dependent epimerase/dehydratase family),
score=721.7, E=3.2e-213, N=1 [Salmonella typhimurium
LT2]
Length = 355
Score = 134 bits (334), Expect = 1e-30
Identities = 105/333 (31%), Positives = 162/333 (48%), Gaps = 38/333 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEE--NDVVVIDNL-YSGKPENVPEGVK-----FIEADVR 55
K I+VTGGAGFIGS + + E + VVV+D L Y+G ++ + F + D+
Sbjct: 2 KRILVTGGAGFIGSAVVRHIIHETADAVVVVDKLTYAGNLMSLASVAQSDRFAFEKVDIC 61
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS------EG 107
D S+ + D V H AA+ V+ S+ P E N++GT +L A +
Sbjct: 62 DRASLERVFQQYQPDSVMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWSALDA 121
Query: 108 NGKLIFA----SSAAVYGEPTSLP--IREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVP 161
+ K F S+ VYG+ + E P P SPY SK S +H + + + YG+P
Sbjct: 122 DAKAAFRFHHISTDEVYGDLHTADDFFTETTPYAPSSPYSASKASSDHLVRAWLRTYGLP 181
Query: 162 TVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILV 221
T++ N YGP +I + + AL G+PL ++G+G+Q RD++YV+D A V
Sbjct: 182 TLVTNCSNNYGPYHFP--EKLIPLMILNALAGKPLPVYGNGQQIRDWLYVEDHARALYHV 239
Query: 222 AEKRRAEGETFNVGTGRETTIIELAMKII----ELSSTSSQ--------ILFSKPRPGDI 269
A GET+N+G E +++ I EL+ Q I F RPG
Sbjct: 240 V-TNGAVGETYNIGGHNERKNLDVVRTICALLEELAPQKPQGVVNYHDLITFVDDRPGHD 298
Query: 270 RRSVADIEKI-KKLGFKPRYSLEEGLLETWKWF 301
R D KI ++LG+ P+ + E G+ +T +W+
Sbjct: 299 LRYAIDASKIARELGWTPQETFESGMRKTVQWY 331
>gb|AAF78483.1|AC012187_3 (AC012187) Strong similarity to UDPglucose 4-epimerase from
Arabidopsis thaliana gi|2129759 and is a member of the
NAD dependent Epimerase/Dehydratase PF|01370 family.
ESTs gb|AI100184, gb|T22969, gb|T22968, gb|H76416,
gb|AI998807 come from this gene
Length = 351
Score = 134 bits (334), Expect = 1e-30
Identities = 101/338 (29%), Positives = 170/338 (49%), Gaps = 36/338 (10%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-----------EGVKFIEAD 53
I+VTGGAGFIG+H + + LK+ V +IDN + E V + + F D
Sbjct: 9 ILVTGGAGFIGTHTVVQLLKDGFKVSIIDNFDNSVIEAVDRVRELVGPDLSKKLDFNLGD 68
Query: 54 VRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKL 111
+R+ I ++ S D V H A +V ESV++P + N++GTIN+ +++ N K+
Sbjct: 69 LRNKGDIEKLFSKQRFDAVIHFAGLKAVGESVENPRRYFDNNLVGTINLYETMAKYNCKM 128
Query: 112 -IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV-PTVILRYFN 169
+F+SSA VYG+P +P ED L ++PYG +K+ E + + ++LRYFN
Sbjct: 129 MVFSSSATVYGQPEKIPCMEDFELKAMNPYGRTKLFLEEIARDIQKAEPEWRIILLRYFN 188
Query: 170 VYGPRQSSAYA----GV---ISIFMERALRGE--PLVIFG------DGKQSRDFVYVKDV 214
G +S + G+ + ++++ G L ++G DG RD+++V D+
Sbjct: 189 PVGAHESGSIGEDPKGIPNNLMPYIQQVAVGRLPELNVYGHDYPTEDGSAVRDYIHVMDL 248
Query: 215 VEANILVAEKRRAEGE----TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIR 270
+ +I K A+ + +N+GTG+ T+++E+ + S I R GD
Sbjct: 249 ADGHIAALRKLFADPKIGCTAYNLGTGQGTSVLEMVAAFEKASGKKIPIKLCPRRSGDAT 308
Query: 271 RSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A EK K+LG+K +Y ++E + WKW + G
Sbjct: 309 AVYASTEKAEKELGWKAKYGVDEMCRDQWKWANNNPWG 346
>gb|AAG09513.1|AF279619_1 (AF279619) dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]
Length = 361
Score = 134 bits (334), Expect = 1e-30
Identities = 106/339 (31%), Positives = 162/339 (47%), Gaps = 42/339 (12%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVV-IDNL-YSGKPENVPEGVK-----FIEADVRDY 57
I+VTGGAGFIGS + +K+ D VV +D L Y+G E++ E + F AD+ D
Sbjct: 3 ILVTGGAGFIGSAVVRHIIKDTQDTVVNVDKLTYAGNLESLTEVSESHRYHFEHADICDK 62
Query: 58 ESIAEI--VSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
++ I D V H AA+ V+ S+ P E N++GT +L A L
Sbjct: 63 AAMERIFVTHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARSYWNALDVEK 122
Query: 116 SAA----------VYGE---------PTSLPI-REDHPLNPISPYGVSKVSGEHYCKVFY 155
AA VYG+ + LP+ E P SPY SK S +H + +
Sbjct: 123 KAAFRFHHISTDEVYGDLPHPDEVSAGSVLPLFTEKTAYAPSSPYSASKASSDHLVRAWL 182
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
+ YG PT++ N YGP +I + + AL G+ L I+G G Q RD++YV+D
Sbjct: 183 RTYGFPTIVTNCSNNYGPYHFP--EKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHA 240
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL--------SSTSSQILFSKPRPG 267
A + + GET+N+G E +++ I +L + Q+++ RPG
Sbjct: 241 RA-LYTVVTQGVVGETYNIGGHNEKKNLDVVQTICDLLDEIVPKEGAYRDQLIYVTDRPG 299
Query: 268 DIRRSVADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRT 305
RR D KI +LG+KP+ + E G+ +T +W+ + T
Sbjct: 300 HDRRYAIDAAKISDELGWKPQETFESGIRKTVEWYLNNT 338
>emb|CAC11487.1| (AL445064) nucleotide sugar epimerase related protein [Thermoplasma
acidophilum]
Length = 307
Score = 133 bits (331), Expect = 3e-30
Identities = 95/317 (29%), Positives = 168/317 (52%), Gaps = 30/317 (9%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPEN---VPEGVKFIE---ADV 54
+R K I+VTGGAGFIGS++ L +EN V V+D+L +G N V +G+ F++ A+V
Sbjct: 3 IRGKEILVTGGAGFIGSNLVIRLAKENHVYVLDDLQTGSLRNLSSVYDGIDFVKDRVANV 62
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIG-----TINILRALSEGNG 109
DY DY+FH S P++ + +++G +++L
Sbjct: 63 NDY------CFDPDYIFHIGLYSS------SPMYKDNPHLVGELIKDMVSVLELAKRKKS 110
Query: 110 KLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
+++AS++++Y P RED Y ++ + E +++ +LYG+ +R+F+
Sbjct: 111 TVVYASTSSIY-NGVKPPHREDVIPFVTDFYTEARYATERISELYSKLYGINISAMRFFS 169
Query: 170 VYG--PRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRA 227
VYG R +A ++S F+ G+ VI+GDG+Q RDFV+V DVV+A ++ A
Sbjct: 170 VYGYNERSKKKFANLVSQFIWDMHDGKQPVIYGDGEQKRDFVFVDDVVDA-LINAAVYNT 228
Query: 228 EGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGD--IRRSVADIEKI-KKLGF 284
+NVGTG+ ++ EL K+ + T + + + + ++AD +K +K+ F
Sbjct: 229 GFNVYNVGTGKNYSLNELVQKLNDHMHTDIKAKYVENPMAKTYVHETLADTKKSEEKIKF 288
Query: 285 KPRYSLEEGLLETWKWF 301
K + SL+EG+ + K++
Sbjct: 289 KAKISLDEGIDKLMKYY 305
>sp|P14169|RFBE_SALTI CDP-TYVELOSE-2-EPIMERASE >gi|861175|gb|AAB49384.1| (M29682)
CDP-tyvelose epimerase [Salmonella enterica]
Length = 338
Score = 132 bits (330), Expect = 4e-30
Identities = 94/335 (28%), Positives = 171/335 (50%), Gaps = 37/335 (11%)
Query: 6 IVVTGGAGFIGSHIAE-ALKEENDVVVIDNLY-SGKPENVP-----EGVKFIEADVRDYE 58
+++TGG GF+GS++A AL + D++V DNL G +N+ +F+ D+R+
Sbjct: 3 LLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWLSSLGNFEFVHGDIRNKN 62
Query: 59 SIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK--LIFA 114
+ +++ D FH A Q+++ S+ +P E+NV GT+N+L A+ + N +I++
Sbjct: 63 DVTRLITKYMPDSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEAVRQYNSNCNIIYS 122
Query: 115 SSAAVYGEPTSLPIRE--------DHP--------LNPISPYGVSKVSGEHYCKVFYQLY 158
S+ VYG+ E D P L+ SPYG SK + + Y + +++
Sbjct: 123 STNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQYMLDYARIF 182
Query: 159 GVPTVILRYFNVYGPRQSSAY-AGVISIFMERALR-----GEPLVIFGDGKQSRDFVYVK 212
G+ TV+ R+ ++YG RQ + Y G + F ++A+ +P I G+GKQ RD ++ +
Sbjct: 183 GLNTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGNGKQVRDVLHAE 242
Query: 213 DVVEANI-LVAEKRRAEGETFNVG--TGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
D++ +A + G FN+G +++EL + + + + R D
Sbjct: 243 DMISLYFTALANVSKIRGNAFNIGGTIVNSLSLLELFKLLEDYCNIDMRFTNLPVRESDQ 302
Query: 270 RRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKS 303
R VADI+KI + + P+ S ++G+ + + W S
Sbjct: 303 RVFVADIKKITNAIDWSPKVSAKDGVQKMYDWTSS 337
>gb|AAF01814.1|AF187532_10 (AF187532) putative dTDP-glucose-4,6-dehydratase [Streptomyces
nogalater]
Length = 350
Score = 132 bits (330), Expect = 4e-30
Identities = 98/314 (31%), Positives = 155/314 (49%), Gaps = 20/314 (6%)
Query: 6 IVVTGGAGFIGSHIAEALKEEND---------VVVIDNL-YSGKPENVP----EGVKFIE 51
I+VTG GFIGS L E V V+D L Y+G N+ + ++F+
Sbjct: 13 ILVTGAVGFIGSAYVRMLLENRAPGAGAPAVRVTVLDKLTYAGNLTNLDAVRGDRLRFVR 72
Query: 52 ADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGK 110
D+ D E + E+++ +D V H AA+ V+ S++ NV+GT +L AL G
Sbjct: 73 GDILDAELVDELMAHSDQVVHFAAESHVDRSIRAADDFVLTNVVGTQRLLDAALRHGVEP 132
Query: 111 LIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
+ S+ VYG S E+HPL+P SPY SK S + ++ +G+ + R N
Sbjct: 133 FVLVSTDEVYGSIASGSWPEEHPLSPNSPYAASKASADLMAFACHRTHGLDVRVTRCSNN 192
Query: 171 YGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
YGPRQ +I F+ L G P+ ++GDG+ R++++V+D LV R G
Sbjct: 193 YGPRQHP--EKLIPRFVTNLLDGLPVPLYGDGRNVREWLHVEDHCRGVDLVRTAGR-PGG 249
Query: 231 TFNVGTGRETTIIELAMKIIELSSTS-SQILFSKPRPG-DIRRSVADIEKIKKLGFKPRY 288
+++G GRE + EL ++EL S + R G D+R S+ ++LG++P
Sbjct: 250 VYHIGGGRELSNRELVGMLLELCGADWSSVRHVPDRKGHDLRYSLDWGRAREELGYRPAR 309
Query: 289 SLEEGLLETWKWFK 302
GL T +W++
Sbjct: 310 EFSSGLRSTVQWYR 323
>pir||G83471 UDP-glucose 4-epimerase PA1384 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9947329|gb|AAG04773.1|AE004568_2
(AE004568) UDP-glucose 4-epimerase [Pseudomonas
aeruginosa]
Length = 337
Score = 132 bits (329), Expect = 5e-30
Identities = 108/336 (32%), Positives = 165/336 (48%), Gaps = 37/336 (11%)
Query: 6 IVVTGGAGFIGSHI-AEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVRDY 57
++VTGGAGFIGSH+ E L + VVV+DNL +G E++ V F+ DVRD
Sbjct: 3 VLVTGGAGFIGSHVLVELLGQGAKVVVLDNLVNGSSESLKRVERITGHPVGFVLGDVRDS 62
Query: 58 ESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
+ ++ D V H A +V ESV DP+ E NV GTI++LRA+ G K++F+
Sbjct: 63 LLVERLLIDEKVDAVIHLAGLKAVGESVDDPLEYYESNVQGTISLLRAMQRVGVFKIVFS 122
Query: 115 SSAAVYGEPTSLPIREDHPLNPI-SPYGVSKVSGEHYCKVFYQLYGVPT----VILRYFN 169
SSA +Y P +LPI E + + SPYG +K++ EH + L T +LRYFN
Sbjct: 123 SSATIYQMPGTLPISESSKVGGVASPYGRTKLTAEH---MLDDLARSDTRWSIAVLRYFN 179
Query: 170 VYGPRQSSAYA--------GVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDV 214
G +S ++ + A+ R L + G DG RD+++V D+
Sbjct: 180 PIGAHESGLIGEDPCGTPNNLLPYIAQVAVGRLSRLTVHGGDYPTIDGTGVRDYIHVCDL 239
Query: 215 VEANILVAE-KRRAEG-ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRS 272
+ E + G +N+GTG +++++ +S S RPGD+
Sbjct: 240 AAGHTRALEYLGQGHGYHVWNLGTGTGYSVLQVIEAFERVSGRRIPFTVSGRRPGDVAEC 299
Query: 273 VADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
AD+ K ++LG+K LE + + W+W S G
Sbjct: 300 WADVSKAERELGWKAGLGLECMIADAWRWQVSNPSG 335
>pir||T51106 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [validated] -
Streptomyces antibioticus (ATCC 11891)
>gi|5902170|gb|AAD55454.1| (AF055579) dehydratase
[Streptomyces antibioticus]
Length = 335
Score = 132 bits (328), Expect = 6e-30
Identities = 96/311 (30%), Positives = 152/311 (48%), Gaps = 17/311 (5%)
Query: 6 IVVTGGAGFIGS----HIAEALKEEND----VVVIDNL-YSGKPENVPE--GVKFIEADV 54
++VTG AGFIGS H+ EA + + + V+D L Y+G NVP+ V F+ D+
Sbjct: 3 LLVTGAAGFIGSRYVHHLLEATRRGREPAPVITVLDKLTYAGVLGNVPDDPAVTFVRGDI 62
Query: 55 RDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGKLIF 113
D + +++ AD V H AA+ V+ S+ P NV+GT +L AL G G +
Sbjct: 63 ADAPLVDSLMAEADQVVHFAAETHVDRSITSPGTFVRTNVLGTQVLLDAALRHGVGPFVH 122
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
S+ VYG E PL P SPY SK S + +++ +G+ + R N YGP
Sbjct: 123 VSTDEVYGSIEHGSWPEHQPLCPNSPYSASKASSDLLALSYHRTHGLDVRVTRCSNNYGP 182
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
Q ++ +F+ L G + ++GDG R++++V D LV + R GE ++
Sbjct: 183 HQFP--EKIVPLFVTNLLDGLRVPLYGDGLNVREWLHVDDHCLGVDLVRTQGR-PGEVYH 239
Query: 234 VGTGRETTIIELAMKIIELSSTSSQILFS-KPRPGDIRRSVADIEK-IKKLGFKPRYSLE 291
+G G E T +L +++ ++ R G RR D K +LG++PR
Sbjct: 240 IGGGTELTNRDLTGLLLDAFGVGWDVVDPVADRKGHDRRYALDCAKAADELGYRPRRDFA 299
Query: 292 EGLLETWKWFK 302
EG+ T W++
Sbjct: 300 EGIARTIDWYR 310
>pir||T44844 UDPglucose 4-epimerase (EC 5.1.3.2) [imported] - Acinetobacter
lwoffii >gi|6010005|emb|CAB57212.1| (AJ243431) putative
UDP-glucose 4-epimerase [Acinetobacter lwoffii]
Length = 338
Score = 131 bits (327), Expect = 8e-30
Identities = 102/333 (30%), Positives = 168/333 (49%), Gaps = 31/333 (9%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENV-------PEGVKFIEADVRDY 57
I+VTGGAG+IGSH E L ++V+V DNL + E + + + FI+ D+R+
Sbjct: 4 ILVTGGAGYIGSHTCIELLNAGHEVIVFDNLSNSSEEALRRVQKLTNKSLVFIQGDIRNQ 63
Query: 58 ESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
+ + D V H A +V ES + P+ + N+ G+I + +++ + G KL+F+
Sbjct: 64 SELDLVFQDHQIDAVIHFAGLKAVGESQQIPLTYFDNNIAGSIQLTKSMEKAGVFKLVFS 123
Query: 115 SSAAVYGEPTSLPIREDHPLN-PISPYGVSKVSGEHYC-KVFYQLYGVPTVILRYFNVYG 172
SSA VY E + P+ ED P + YG +K+ E K+ + +LRYFN G
Sbjct: 124 SSATVYDEVNTSPLNEDMSTGIPNNNYGYTKLIVEQLLQKLAHADRRWSIALLRYFNPVG 183
Query: 173 PRQSSAYA----GVISIFMERAL-----RGEPLVIFG------DGKQSRDFVYVKDVVEA 217
+S G+ + M R E L I+G DG RD+++V D+ A
Sbjct: 184 AHKSGQIGEDPQGIPNNLMPYVTQVAVGRREKLSIYGNDYDTVDGTGVRDYIHVVDLANA 243
Query: 218 NILVAEKR-RAEG-ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
++ R A+G +N+GTG ++++++ +++ S F R GD+ S AD
Sbjct: 244 HLCALSNRLSAQGCRVWNIGTGNGSSVLQVKNTFEQVNGVSIAFEFVSRRAGDVATSFAD 303
Query: 276 IEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
+ + +LG+KP+YSLE+ L ++W W K G
Sbjct: 304 NTRAQLELGWKPQYSLEDMLTDSWNWQKQNPNG 336
>dbj|BAB09155.1| (AB017065) contains similarity to UDP-glucose
4-epimerase~gene_id:MFC16.15 [Arabidopsis thaliana]
Length = 436
Score = 131 bits (326), Expect = 1e-29
Identities = 109/331 (32%), Positives = 161/331 (47%), Gaps = 34/331 (10%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENVPE---------GVKFIEADVR 55
++VTGGAG+IGSH A L++ V ++DNL G V ++FI AD+
Sbjct: 97 VLVTGGAGYIGSHAALRLLRDSYRVTIVDNLSRGNLGAVKTLQQLFPQTGRLQFIYADLG 156
Query: 56 DYESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLI 112
D ++ +I S + D V H AA V ES P+ T+ +L A++ KLI
Sbjct: 157 DPLAVEKIFSENAFDAVMHFAAVAYVGESTLYPLKYYHNITSNTLGVLEAMARHKVKKLI 216
Query: 113 FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
++S+ A YGEP +PI ED P PI+PYG +K E F + + +ILRYFNV G
Sbjct: 217 YSSTCATYGEPEKMPITEDTPQVPINPYGKAKKMAEDMILDFSKNSDMAVMILRYFNVIG 276
Query: 173 ----------PRQSSAYAGVISIFMERALRG--EPLVIFG------DGKQSRDFVYVKDV 214
PR G IS A RG L + G DG RD++ V D+
Sbjct: 277 SDPGGRLGEAPRPELREQGRISGACFDAARGFIPGLQVKGTDYKTSDGTCIRDYIDVTDL 336
Query: 215 VEANILVAEKRR-AEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
V+A++ EK + + +NVGTG+ ++ E + + ++ F RPGD
Sbjct: 337 VDAHVKALEKAQPRKVGIYNVGTGKGRSVKEFVEACKKATGVEIKVDFLPRRPGDYAEVY 396
Query: 274 ADIEKI-KKLGFKPRY-SLEEGLLETWKWFK 302
+D KI K L + R+ +L++ L W+W K
Sbjct: 397 SDPTKILKDLNWTARFTNLQDSLQVAWRWQK 427
>sp|P55294|RFBB_NEIMB DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|7437244|pir||S42431 dTDPglucose
4,6-dehydratase (EC 4.2.1.46) - Neisseria meningitidis
(isolate B1940) >gi|388933|gb|AAA63157.1| (L09188)
TDP-glucose-dehydratase [Neisseria meningitidis]
Length = 360
Score = 131 bits (325), Expect = 1e-29
Identities = 104/333 (31%), Positives = 159/333 (47%), Gaps = 38/333 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEAL--KEENDVVVIDNL-YSGKPENVPE-----GVKFIEADVR 55
K I+VTGGAGFIGS + + ++ VV +D L Y+G E++ + F + D+
Sbjct: 7 KTILVTGGAGFIGSAVVRHIIRNTQDSVVNLDKLTYAGNLESLTDIADNPRYAFEQVDIC 66
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL--------S 105
D + + + D V H AA+ V+ S+ + N++GT N+L A S
Sbjct: 67 DRAELDRVFAQHRPDAVMHLAAESHVDRSIGSAGEFIQTNIVGTFNLLEAARAYWQQMPS 126
Query: 106 EGNGKLIF--ASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVP 161
E + F S+ VYG+ T E P P SPY SK S +H + + + YG+P
Sbjct: 127 EQHEAFRFHHISTDEVYGDLHGTDDLFTETTPYAPSSPYSASKASSDHLVRAWLRTYGLP 186
Query: 162 TVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILV 221
T++ N YGP +I + + AL G+PL ++GDG Q RD+++V+D A V
Sbjct: 187 TIVTNCSNNYGPYHFP--EKLIPLMILNALDGKPLPVYGDGMQIRDWLFVEDHARALYQV 244
Query: 222 AEKRRAEGETFNVGTGRETTIIELAMKIIEL------------SSTSSQILFSKPRPGDI 269
+ GET+N+G E IE+ I L + I F + RPG
Sbjct: 245 VTE-GVVGETYNIGGHNEKANIEVVKTICTLLEELVPEKPAGVARYEDLITFVQDRPGHD 303
Query: 270 RRSVADIEKIKK-LGFKPRYSLEEGLLETWKWF 301
R D KI++ LG+ P + E GL +T +W+
Sbjct: 304 VRYAVDAAKIRRDLGWLPLETFESGLRKTVQWY 336
>gb|AAD05454.1| (AF064070) putative dTDP-D-glucose 4,6-dehydratase [Burkholderia
pseudomallei]
Length = 353
Score = 131 bits (325), Expect = 1e-29
Identities = 97/334 (29%), Positives = 159/334 (47%), Gaps = 45/334 (13%)
Query: 5 LIVVTGGAGFIGSH-IAEALKEENDVVV-IDNL-----------YSGKPENVPEGVKFIE 51
+I+VTGGAGFIG++ + + L + ++ V+ +D L G P++V F
Sbjct: 1 MILVTGGAGFIGANFVLDWLAQSDEAVLNVDKLTYAGNLGTLKSLQGNPKHV-----FAR 55
Query: 52 ADVRDYESIAEIVSSAD--YVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL----- 104
D+ D +I +++ + H AA+ V+ S+ P + NV+GT +L A
Sbjct: 56 VDICDRAAIDALLAQHKPRAIVHFAAESHVDRSIHGPADFVQTNVVGTFTLLEAARQYWS 115
Query: 105 -----SEGNGKLIFASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQL 157
++ + + S+ V+G P E P P SPY +K +H + ++
Sbjct: 116 ALGPDAKAAFRFLHVSTDEVFGSLSPADPQFSETTPYAPNSPYSATKAGSDHLVRAYHHT 175
Query: 158 YGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEA 217
YG+P + N YGP Q +I + + AL G+PL ++GDG+ RD++YV D A
Sbjct: 176 YGLPVLTTNCSNNYGPYQFP--EKLIPLMIANALGGKPLPVYGDGQNVRDWLYVGDHCSA 233
Query: 218 NILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL---------SSTSSQILFSKPRPGD 268
I R GET+NVG E +++ + +L S QI + RPG
Sbjct: 234 -IREVLARGVPGETYNVGGWNEKKNLDVVHTLCDLLDEARPKAGGSYRDQITYVTDRPGH 292
Query: 269 IRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWF 301
RR D K+ ++LG+KP + E GL +T +W+
Sbjct: 293 DRRYAIDARKLERELGWKPAETFETGLAKTVRWY 326
>gb|AAC12869.1| (AF044332) dTDP-D-glucose-4,6-dehydratase; RffG [Pectobacterium
carotovorum subsp. atrosepticum]
Length = 357
Score = 129 bits (322), Expect = 3e-29
Identities = 104/336 (30%), Positives = 154/336 (44%), Gaps = 38/336 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEE--NDVVVIDNL-YSGK-----PENVPEGVKFIEA 52
M K I++TGGAGFIGS + + E + VVV+D L Y+G P F +
Sbjct: 1 MALKRILITGGAGFIGSALVRYILAETQDSVVVVDKLTYAGNLSSLAPVADSSRFAFEQV 60
Query: 53 DVRDYESIAEIVSSAD--YVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK 110
D+ D + + ++ V H AA+ V+ S+ P E N++GT +L A
Sbjct: 61 DICDRAELDRVFTAYQPALVMHLAAESHVDRSIDGPAAFIETNIVGTYTMLEAARHYWQN 120
Query: 111 LIFASSAA----------VYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLY 158
L A A V+G+ T E P P SPY SK S +H + + + Y
Sbjct: 121 LADADKNAFRFHHISTDEVFGDLHGTDDLFTETTPYAPSSPYSASKASSDHLVRAWLRTY 180
Query: 159 GVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEAN 218
G PTVI N YGP +I + + A+ G+PL ++GDG Q RD+++V+D A
Sbjct: 181 GFPTVITNCSNNYGPYHFP--EKLIPLVILNAVAGKPLPVYGDGAQIRDWLFVEDHARAL 238
Query: 219 ILVAEKRRAEGETFNVGTGRETTIIELAMKIIEL------------SSTSSQILFSKPRP 266
V + GET+N+G E IE+ I L + I + K RP
Sbjct: 239 YKVVTEGEV-GETYNIGGHNERKNIEVVQTICALLEELAPNKPAGVAHYRDLITYVKDRP 297
Query: 267 GDIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWF 301
G R D KI ++LG++P + E G+ +T W+
Sbjct: 298 GHDMRYAIDAGKIERELGWRPEETFETGMKKTVSWY 333
>gb|AAD50494.1|AF172324_12 (AF172324) WbnF [Escherichia coli]
Length = 334
Score = 129 bits (322), Expect = 3e-29
Identities = 95/329 (28%), Positives = 159/329 (47%), Gaps = 34/329 (10%)
Query: 7 VVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEG---------VKFIEADVRD 56
+VTG AGFIG ++++ L + VV IDNL N+ + F + D+ D
Sbjct: 4 LVTGAAGFIGFYVSKRLLAAGHQVVGIDNLNDYYDVNLKQARLDLLKHDNFSFYKIDLAD 63
Query: 57 YESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIF 113
E +A + + D V + AAQ V S+++P + N+IG +NIL N + L++
Sbjct: 64 REKMAALFADERFDRVINLAAQAGVRYSLENPNAYADANLIGFLNILEGCRHNNVQHLLY 123
Query: 114 ASSAAVYGEPTSLPIREDHPLN-PISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
ASS++VYG +P D ++ P+S Y +K + E + LYG+PT LR+F VYG
Sbjct: 124 ASSSSVYGMNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPTTGLRFFTVYG 183
Query: 173 PRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANI----LVAEK---- 224
P A + F + L G+ + ++ GK RDF Y+ D+ EA I ++ EK
Sbjct: 184 PWGRPDMA--LFKFTKAMLEGKSIDVYNFGKMKRDFTYIDDIAEAIIRLQDVIPEKDPQW 241
Query: 225 ---------RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
A +N+G +++ + E + +PGD+ + AD
Sbjct: 242 TVETGSPATSSAPYRVYNIGNSSPVELMDYINALEEALGIEANKNMMPLQPGDVLETSAD 301
Query: 276 IEKI-KKLGFKPRYSLEEGLLETWKWFKS 303
+ + +GFKP S++EG+ +W+++
Sbjct: 302 TKALYDVIGFKPETSVKEGVKNFVEWYRN 330
>pir||T48867 dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [validated] -
Streptomyces argillaceus >gi|1814005|emb|CAA71847.1|
(Y10907) TDP-D-Glucose-4,6,-dehydratase [Streptomyces
argillaceus] >gi|3334820|emb|CAA07755.1| (AJ007932)
dTDP-glucose 4,6-dehydratase [Streptomyces argillaceus]
Length = 331
Score = 129 bits (321), Expect = 4e-29
Identities = 97/316 (30%), Positives = 152/316 (47%), Gaps = 17/316 (5%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALK-----EENDVVVIDNL-YSGKPENVPE-----GVKF 49
M I+VTGGAGFIGSH L + V V+D L Y+G N+ E +F
Sbjct: 1 MTTTSILVTGGAGFIGSHYVRTLLGPRGVPDVTVTVLDKLTYAGTLTNLAEVSDSDRFRF 60
Query: 50 IEADVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGN 108
+ D+ D + ++++ D V H AA+ V+ S+ NV GT +L AL +G
Sbjct: 61 VRGDICDAPLVDDLLAVHDQVVHFAAESHVDRSILGAADFVRTNVTGTQTLLDAALRQGI 120
Query: 109 GKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYF 168
+ S+ VYG + E P++P S Y +K S + +++ +G+ + R
Sbjct: 121 ETFVHISTDEVYGSIDAGSWPETAPVSPNSLYSAAKASSDLVALAYHRTHGLDVRVTRCS 180
Query: 169 NVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAE 228
N YG Q VI +F+ L G + ++GDG RD+++V D V A LV RA
Sbjct: 181 NNYGSHQFPEK--VIPLFVTSLLDGREVPLYGDGTNVRDWLHVDDHVRAIELVRTGGRA- 237
Query: 229 GETFNVGTGRETTIIELAMKIIELSSTS-SQILFSKPRPGDIRRSVADIEKIKK-LGFKP 286
GE +N+G G E + EL +++ ++ + R G RR D KI++ LG++P
Sbjct: 238 GEVYNIGGGTELSNKELTQLLLDACGAGWDRVRYVTDRKGHDRRYSVDCTKIRRELGYRP 297
Query: 287 RYSLEEGLLETWKWFK 302
+ L ET W++
Sbjct: 298 AREFGDALAETVAWYR 313
>gb|AAG12659.1|AC010795_3 (AC010795) uridine diphosphate glucose epimerase, putative;
80611-78786 [Arabidopsis thaliana]
Length = 353
Score = 129 bits (320), Expect = 5e-29
Identities = 98/340 (28%), Positives = 167/340 (48%), Gaps = 38/340 (11%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVPE-----------GVKFIEAD 53
I+VTGGAGFIG+H + + L + V +IDNL + E V ++F D
Sbjct: 9 ILVTGGAGFIGTHTVVQLLNQGFKVTIIDNLDNSVVEAVHRVRELVGPDLSTKLEFNLGD 68
Query: 54 VRDYESIAEIVSSA----DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNG 109
+R+ I ++ S+ D V H A +V ESV +P + N++GTIN+ +++ N
Sbjct: 69 LRNKGDIEKLFSNQRNRFDAVIHFAGLKAVGESVGNPRRYFDNNLVGTINLYETMAKYNC 128
Query: 110 KL-IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV-PTVILRY 167
K+ +F+SSA VYG+P +P ED L ++PYG +K+ E + + ++LRY
Sbjct: 129 KMMVFSSSATVYGQPEIVPCVEDFELQAMNPYGRTKLFLEEIARDIHAAEPEWKIILLRY 188
Query: 168 FNVYGPRQSSAYA----GV---ISIFMERALRGE--PLVIFG------DGKQSRDFVYVK 212
FN G +S G+ + ++++ G L +FG DG RD+++V
Sbjct: 189 FNPVGAHESGRIGEDPKGIPNNLMPYIQQVAVGRLPELNVFGHDYPTMDGSAVRDYIHVM 248
Query: 213 DVVEANILVAEKRRAEGE----TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGD 268
D+ + ++ K ++ + +N+GTG+ T+++E+ + S I R GD
Sbjct: 249 DLADGHVAALNKLFSDSKIGCTAYNLGTGQGTSVLEMVSSFEKASGKKIPIKLCPRRAGD 308
Query: 269 IRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A +K K+LG+K +Y ++E + W W G
Sbjct: 309 ATAVYASTQKAEKELGWKAKYGVDEMCRDQWNWANKNPWG 348
>gb|AAG29802.1| (AF235050) dTDP-glucose 4,6-dehydratase [Streptomyces rishiriensis]
Length = 336
Score = 129 bits (320), Expect = 5e-29
Identities = 92/314 (29%), Positives = 151/314 (47%), Gaps = 19/314 (6%)
Query: 6 IVVTGGAGFIGSHIAEAL-------KEENDVVVIDNL-YSGKPENVP-----EGVKFIEA 52
++VTGGAGFIGS A + V+D L YSG N+ E +F++
Sbjct: 3 LLVTGGAGFIGSEFVRATLRGVLPGSSGTQITVLDKLTYSGNELNLAPIADLETYRFVQG 62
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKL 111
D+ D + ++V+ D + H AA+ V+ S++ N +GT +L A S G+
Sbjct: 63 DICDRGLVDDVVAGHDAIVHFAAETHVDRSIEGAASFVRTNALGTQVLLEAASRHRLGRF 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG + E P+ P +PY +K +G+ +++ + V+ R N Y
Sbjct: 123 VHISTDEVYGSISEGAWTEASPVAPNAPYAAAKAAGDLLALAWHRTRKLDVVVTRCTNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GP Q +I +F L G+ + ++GDG R +++V D A V R GE
Sbjct: 183 GPYQYP--EKLIPLFTTNLLDGQQVPVYGDGHNRRQWLHVSDHCRAIQCVLLGGR-PGEV 239
Query: 232 FNVGTGRETTIIELAMKIIELSSTS-SQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYS 289
+++G G E T +EL I+E ++ R G R D KI+ +LG+ PR +
Sbjct: 240 YHIGGGTELTNLELTEHILEACGAGWDRVRHVPDRLGHDLRYSLDTTKIRTELGYSPRVA 299
Query: 290 LEEGLLETWKWFKS 303
+GL ET +W+++
Sbjct: 300 FADGLAETVEWYRT 313
>pir||S42430 UDPglucose 4-epimerase (EC 5.1.3.2) galE [similarity] - Neisseria
meningitidis (isolate B1940) >gi|388932|gb|AAA63156.1|
(L09188) UPD-glucose-4-epimerase [Neisseria
meningitidis]
Length = 339
Score = 128 bits (318), Expect = 9e-29
Identities = 101/328 (30%), Positives = 161/328 (48%), Gaps = 31/328 (9%)
Query: 4 KLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVR 55
K I+VTGG GFIGSH + LK + VV++DNL + +P + + F + D+R
Sbjct: 2 KKILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRLKTITGQEIPFYQGDIR 61
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLI 112
D E + I + D V H A +V ESV +P+ + NV G++ + ++ G ++
Sbjct: 62 DREILRRIFAENRIDSVIHFAGLKAVGESVAEPMKYYDNNVSGSLVLAEEMARAGVFSIV 121
Query: 113 FASSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQLYGVPTVI-LRYFNV 170
F+SSA VYG+P +P ED PL + SPYG SK E + +VI LRYFN
Sbjct: 122 FSSSATVYGDPGKVPYTEDMPLGDTTSPYGTSKSMVERILTDIQKADPRWSVILLRYFNP 181
Query: 171 YGPRQSSAYA----GVIS-----IFMERALRGEPLVIFG------DGKQSRDFVYVKDVV 215
G +S G+ + I A + L +FG DG RD+++V D+
Sbjct: 182 IGAHESGLIGEQPNGIPNNLLPYICQVAAGKLPQLAVFGDDYPTPDGTGMRDYIHVMDLA 241
Query: 216 EANILVAEKRR--AEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
E ++ + + A FN+G+GR +++E+ S + R GD+ S
Sbjct: 242 EGHVAAMQAKGGVAGVHLFNLGSGRAYSVLEIIRAFEAASGLNIPYQIQPRRAGDLACSF 301
Query: 274 ADIEKIK-KLGFKPRYSLEEGLLETWKW 300
AD K + G++ + SL + + ++W+W
Sbjct: 302 ADPSHTKQETGWETKRSLAQMMEDSWRW 329
>gb|AAD05470.1| (AF064070) putative UDP-glucose 4-epimerase [Burkholderia
pseudomallei]
Length = 340
Score = 128 bits (318), Expect = 9e-29
Identities = 107/332 (32%), Positives = 157/332 (47%), Gaps = 30/332 (9%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENVPEGVK-------FIEADVRDY 57
I+VTGGAG+IGSH A E L DVV+ DNL + K E + K F E DV D
Sbjct: 7 ILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDE 66
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFA 114
++A I + H AA +V ESV P+ N+ +++LR + E K ++F+
Sbjct: 67 RALARIFDAHPITAAIHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRERAVKRIVFS 126
Query: 115 SSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCK-VFYQLYGVPTVILRYFNVYGP 173
SSA VYG P PI E PL+ +PYG +K+ E + V LRYFN G
Sbjct: 127 SSATVYGVPERSPIDETFPLSATNPYGQTKLMAEQILRDVEAADPSWRVATLRYFNPVGA 186
Query: 174 RQSSAY----AGVISIFMERAL-----RGEPLVIFG------DGKQSRDFVYVKDVVEAN 218
+S AG+ + M + E L +FG DG RD+++V D+ +
Sbjct: 187 HESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVVDLARGH 246
Query: 219 I--LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD- 275
I L A +RR T N+GTGR +++E+ + S + RPGD+ A+
Sbjct: 247 IAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGRAVPYELVARRPGDVAECYANP 306
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWFKSRTLG 307
+ +G+K LE + W+W ++ G
Sbjct: 307 AAAAETIGWKAERDLERMCADHWRWQENNPRG 338
>sp|Q57301|GALE_YEREN UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|1163935|gb|AAC44470.1| (U43708)
Description: homolog of galE; UDP galactose epimerase
homolog; Method: conceptual translation supplied by
author [Yersinia enterocolitica]
>gi|1197656|gb|AAC60777.1| (U46859) GalE [Yersinia
enterocolitica (type 0:8)] >gi|1588475|prf||2208415E
UDP-galactose 4-epimerase [Yersinia enterocolitica]
Length = 336
Score = 127 bits (317), Expect = 1e-28
Identities = 102/331 (30%), Positives = 157/331 (46%), Gaps = 29/331 (8%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVK-------FIEADVRDY 57
I++TGGAG+IGSH L E+ +VVV+DNL + E++ K F D+ D
Sbjct: 3 ILITGGAGYIGSHTVLTLLEQGRNVVVLDNLINSSAESLARVSKICGRKPNFYHGDILDR 62
Query: 58 ESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFA 114
+ I SS D V H A SV ESV+ P+ + NV+G+I +L + N KLIF+
Sbjct: 63 SCLKLIFSSHKIDSVIHFAGLKSVGESVEKPIEYYQNNVVGSITLLEEMCLANVKKLIFS 122
Query: 115 SSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQLY-GVPTVILRYFNVYG 172
SSA VYGEP +P+ E + +PYG SKV E K F + LRYFN G
Sbjct: 123 SSATVYGEPEFVPLTEKARIGGTTNPYGTSKVMVEQILKDFSLAHPDYSITALRYFNPVG 182
Query: 173 PRQSSAYA--------GVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDVVEA 217
S ++ + A+ + L+++G DG RD+++V D+ E
Sbjct: 183 AHPSGLIGEDPNGKPNNLLPFITQVAIGKLSKLLVYGNDYDTPDGSGIRDYIHVMDLAEG 242
Query: 218 NILVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIE 277
++ + +N+GTG +++ + + ++ + RPGDI A E
Sbjct: 243 HLSTLINLTSGFRIYNLGTGVGYSVLHMIKEFERITGKNIPFDIVSRRPGDIAECWASPE 302
Query: 278 KIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
+LG+ + +L + L + WKW K G
Sbjct: 303 LAHLELGWYAKRTLVDMLQDAWKWQKMNPNG 333
>emb|CAB05928.1| (Z83335) unknown [Streptococcus pneumoniae]
Length = 356
Score = 127 bits (317), Expect = 1e-28
Identities = 105/355 (29%), Positives = 163/355 (45%), Gaps = 57/355 (16%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVI---DNL---------------YSGKPEN 42
MR K I++TG AGFIGS++ L E + I DNL + ++
Sbjct: 1 MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDIALKDYRLLQLNKLIQD 60
Query: 43 VPE-GVKFIEADVRDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTIN 99
PE FI+ D+ D I +I S V + AAQ V S+ +P E N++G N
Sbjct: 61 YPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRYSITNPDVYIESNIVGFHN 120
Query: 100 ILRALSE-------GNGKLIFASSAAVYGEPTSLPIR-EDHPLNPISPYGVSKVSGEHYC 151
+L A G L++ASS++VYG +P ED NPIS Y +K + E
Sbjct: 121 VLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATEDKVDNPISLYAATKKTNELQA 180
Query: 152 KVFYQLYGVPTVILRYFNVYGP--RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFV 209
+ ++Y +P+ LR+F VYGP R AY G F ++ G + I+ G RDF
Sbjct: 181 YAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFG----FTDKLRSGSDIEIYNHGNCKRDFT 236
Query: 210 YVKDVVEANILVAEKR-----------RAEGETFNVGTGRETTIIE----LAMKIIELSS 254
Y+ D+VE + V + A + +N+G + +++ L ++I+
Sbjct: 237 YIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSKPENLLDFVDVLQQELIKAGV 296
Query: 255 TSSQILFSKPR------PGDIRRSVADIEKIKK-LGFKPRYSLEEGLLETWKWFK 302
F + PGD+ + AD +++ GFKP+ SL EGL + +W+K
Sbjct: 297 LPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFKPKTSLREGLRKFAEWYK 351
>gi|6319493 UDP-glucose 4-epimerase; Gal10p [Saccharomyces cerevisiae]
>gi|585169|sp|P04397|GALX_YEAST GAL10 BIFUNCTIONAL
PROTEIN [INCLUDES: UDP-GLUCOSE 4-EPIMERASE
(GALACTOWALDENASE); ALDOSE 1-EPIMERASE (MUTAROTASE)]
>gi|625246|pir||XEBYUG UDPglucose 4-epimerase (EC
5.1.3.2) - yeast (Saccharomyces cerevisiae)
>gi|536222|emb|CAA84961.1| (Z35888) ORF YBR019c
[Saccharomyces cerevisiae]
Length = 699
Score = 127 bits (316), Expect = 2e-28
Identities = 98/344 (28%), Positives = 162/344 (46%), Gaps = 39/344 (11%)
Query: 3 NKLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENV-------PEGVKFIEADV 54
+K+++VTGGAG+IGSH + E ++ D VV DNL + ++V + F E D+
Sbjct: 11 SKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDL 70
Query: 55 RDYESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKL 111
D + + ++ D V H A +V ES + P+ N++GT+ +L + + N K
Sbjct: 71 CDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVLLELMQQYNVSKF 130
Query: 112 IFASSAAVYGE----PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFY--QLYGVPTVIL 165
+F+SSA VYG+ P +PI E+ PL P +PYG +K + E+ Y IL
Sbjct: 131 VFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDLYNSDKKSWKFAIL 190
Query: 166 RYFNVYGPRQSSAYA--------GVISIFMERAL-RGEPLVIFG------DGKQSRDFVY 210
RYFN G S ++ + A+ R E L IFG DG RD+++
Sbjct: 191 RYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRDGTPIRDYIH 250
Query: 211 VKDVVEANILVAEKRRAEGET------FNVGTGRETTIIELAMKIIELSSTSSQILFSKP 264
V D+ + +I + A E +N+G+G+ +T+ E+ + S +
Sbjct: 251 VVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASGIDLPYKVTGR 310
Query: 265 RPGDIRRSVADIEKIKK-LGFKPRYSLEEGLLETWKWFKSRTLG 307
R GD+ A ++ K+ L ++ +E+ + WKW G
Sbjct: 311 RAGDVLNLTAKPDRAKRELKWQTELQVEDSCKDLWKWTTENPFG 354
>pir||F82419 UDP-glucose 4-epimerase VCA0774 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9658197|gb|AAF96672.1| (AE004405)
UDP-glucose 4-epimerase [Vibrio cholerae]
Length = 338
Score = 127 bits (316), Expect = 2e-28
Identities = 103/333 (30%), Positives = 162/333 (47%), Gaps = 32/333 (9%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENVPE-----GVK--FIEADVRDY 57
++VTGG G+IGSH + ++ V++DNLY+ K + GV+ F++ D+RD
Sbjct: 3 VLVTGGMGYIGSHTCIQMIQAGMTPVILDNLYNSKVTVLDRIEKVIGVRPQFVQGDIRDK 62
Query: 58 ESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFA 114
+ +++ + + V H A +V ESV+ P+ + NV GT+ ++ A+ E K L+F+
Sbjct: 63 ALLVDLMQQHNIEAVVHFAGLKAVGESVQKPLEYYDNNVNGTLVLVAAMREAGVKSLVFS 122
Query: 115 SSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGV--PTVILRYFNVYG 172
SSA VYGEPTS+PI E P +PYG SK+ E C +Q +LRYFN G
Sbjct: 123 SSATVYGEPTSVPITESFPTKAANPYGRSKLMVEE-CLTDFQKANPDWSITLLRYFNPVG 181
Query: 173 PRQSSAYA----GVISIFMERAL-----RGEPLVIFG------DGKQSRDFVYVKDVVEA 217
S G+ + M R E L +FG DG RD+++V D+ +
Sbjct: 182 SHPSGELGEDPQGIPNNLMPFVTQVAVGRREYLSVFGSDYPTKDGTGVRDYIHVMDLADG 241
Query: 218 NILVAEK--RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+I +K A +N+GTG+ +++++ S + RPGDI AD
Sbjct: 242 HIAALKKVGTCAGLHIYNLGTGKGYSVLDVVKAFETASGRTVPYKLVDRRPGDIAEYWAD 301
Query: 276 IEK-IKKLGFKPRYSLEEGLLETWKWFKSRTLG 307
K + LG+K +L + W W + G
Sbjct: 302 PTKAAQDLGWKATRNLHTMAQDAWCWQSNNPQG 334
>sp|P09609|GALX_KLULA GAL10 BIFUNCTIONAL PROTEIN [INCLUDES: UDP-GLUCOSE 4-EPIMERASE
(GALACTOWALDENASE); ALDOSE 1-EPIMERASE (MUTAROTASE)]
>gi|68389|pir||XUVKG UDPglucose 4-epimerase (EC 5.1.3.2)
- yeast (Kluyveromyces marxianus var. lactis)
>gi|2819|emb|CAA30090.1| (X07039) transferase (GAL10)
(AA 1 - 687) [Kluyveromyces lactis]
Length = 687
Score = 127 bits (315), Expect = 2e-28
Identities = 96/339 (28%), Positives = 161/339 (47%), Gaps = 34/339 (10%)
Query: 3 NKLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADV 54
+K +VTGGAG+IGSH + E + +V+DNL + E+V + +KF + D+
Sbjct: 4 DKYCLVTGGAGYIGSHTVVELCEAGYKCIVVDNLSNSSYESVARMELLTGQEIKFAKIDL 63
Query: 55 RDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGNGKL 111
+ E + ++ D V H A +V ES + P+ N++GTIN+L + S KL
Sbjct: 64 CELEPLNKLFDDYKIDSVLHFAGLKAVGESTQIPLTYYFNNIVGTINLLECMKSHDVKKL 123
Query: 112 IFASSAAVYGEPT----SLPIREDHPLNPISPYGVSKVSGEHYCK-VFYQLYGVPTVILR 166
+F+SSA VYG+ T +PI E P P +PYG +K++ E + + + ILR
Sbjct: 124 VFSSSATVYGDATRFENMIPIPETCPTGPTNPYGKTKLTIEDMMRDLHFSDKSFSFAILR 183
Query: 167 YFNVYGPRQSSAYAGVISI------FMERALRGE--PLVIFG------DGKQSRDFVYVK 212
YFN G S I FM + G L +FG DG RD+++V
Sbjct: 184 YFNPIGAHPSGVIGEAFGIPNNLLPFMAQVAIGRRPKLYVFGDDYDSVDGTPIRDYIHVV 243
Query: 213 DVVEANILV---AEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
D+ + ++ EK +N+GTG TT++++ + + + + + R GD+
Sbjct: 244 DLAKGHLAALKYLEKYAGTCREWNLGTGHGTTVLQMYRAFCDAIGFNFEYVVTARRDGDV 303
Query: 270 RRSVADIEK-IKKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A ++ +L +K + + ++ WKW + G
Sbjct: 304 LNLTAKCDRATNELEWKTELDVNKACVDLWKWTQDNPFG 342
>gb|AAD45555.1|U70376_20 (U70376) SpcJ [Streptomyces flavopersicus]
Length = 328
Score = 127 bits (315), Expect = 2e-28
Identities = 97/314 (30%), Positives = 152/314 (47%), Gaps = 19/314 (6%)
Query: 6 IVVTGGAGFIGSHIAEAL-----KEEND--VVVIDNL-YSGKPENVPEGV-----KFIEA 52
I+VTGGAGFIGS +L E N V V+D L Y+G N+ +F+
Sbjct: 3 ILVTGGAGFIGSEFVRSLLLTAEPERNTPWVTVLDKLTYAGVAANLDPVAGHPRYRFVRG 62
Query: 53 DVRDYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINIL-RALSEGNGKL 111
D+ D ++ D V H AA+ V+ S+ NV+GT +L A G G+
Sbjct: 63 DICDAHLADHVMRGHDAVVHFAAESHVDRSISGAGPFVTTNVVGTQVMLDAAYRHGVGRF 122
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ S+ VYG + E PL+P SPY SK + +++ +G+ V+ R N Y
Sbjct: 123 VQVSTDEVYGSISEGSWSEGAPLDPNSPYAASKAGADLLAHSYHRTHGMDVVVTRCSNNY 182
Query: 172 GPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGET 231
GPRQ VI +F+ L G + ++GDG+ RD+++V D I +A + GET
Sbjct: 183 GPRQFP--EKVIPLFITNLLDGREVPLYGDGQHMRDWLHVSDHCR-GIRLALRHGKAGET 239
Query: 232 FNVGTGRETTIIELAMKIIELSSTSSQILFSKP-RPG-DIRRSVADIEKIKKLGFKPRYS 289
+++G G E T L ++E + + P R G D+R S+ + LG++
Sbjct: 240 YHIGGGTELTNEALTGLLLEATGRGWDSVRRVPDRKGHDLRYSLRCDNARQHLGYEAEVG 299
Query: 290 LEEGLLETWKWFKS 303
E+GL +T W+++
Sbjct: 300 FEKGLADTVAWYRN 313
>sp|P37761|RFBB_NEIGO DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|628590|pir||S47045 dTDPglucose
4,6-dehydratase (EC 4.2.1.46) - Neisseria gonorrhoeae
>gi|520896|emb|CAA83652.1| (Z32742) dTDP-D-glucose
4,6-dehydratase [Neisseria gonorrhoeae]
>gi|1333793|emb|CAA79718.1| (Z21508) dTDP-D-glucose
4,6-dehydratase [Neisseria gonorrhoeae]
Length = 346
Score = 125 bits (312), Expect = 5e-28
Identities = 101/333 (30%), Positives = 159/333 (47%), Gaps = 38/333 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEE--NDVVVIDNL-YSGKPENVPE-----GVKFIEADVR 55
K I+VTGGAGFIGS + + + + VV +D L Y+G E++ + F + D+
Sbjct: 7 KNILVTGGAGFIGSAVVRHIIQNTRDSVVNLDKLTYAGNLESLTDIADNPRYAFEQVDIC 66
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL--------S 105
D + + + D V H AA+ V+ ++ N++GT ++L A S
Sbjct: 67 DRAELDRVFAQYRPDAVMHLAAESHVDRAIGSAGEFIRTNIVGTFDLLEAARAYWQQMPS 126
Query: 106 EGNGKLIF--ASSAAVYGE--PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVP 161
E F S+ VYG+ T E P P SPY SK + +H + + + Y +P
Sbjct: 127 EKREAFRFHHISTDEVYGDLHGTDDLFTETTPYAPSSPYSASKAAADHLVRAWQRTYRLP 186
Query: 162 TVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILV 221
+++ N YGPRQ +I + + AL G+PL ++GDG Q RD+++V+D A V
Sbjct: 187 SIVSNCSNNYGPRQFP--EKLIPLMILNALSGKPLPVYGDGAQIRDWLFVEDHARALYQV 244
Query: 222 AEKRRAEGETFNVGTGRETTIIELAMKIIEL------------SSTSSQILFSKPRPGDI 269
+ GET+N+G E T +E+ I L + I F + RPG
Sbjct: 245 VTE-GVVGETYNIGGHNEKTNLEVVKTICALLEELAPEKPAGVARYEDLITFVQDRPGHD 303
Query: 270 RRSVADIEKIKK-LGFKPRYSLEEGLLETWKWF 301
R D KI++ LG+ P + E GL +T +W+
Sbjct: 304 ARYAVDAAKIRRDLGWLPLETFESGLRKTVQWY 336
>sp|Q59678|GALE_PASHA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|1304491|gb|AAC44098.1| (U39043) uridine
diphosphogalactose 4-epimerase [Pasteurella haemolytica]
Length = 338
Score = 125 bits (312), Expect = 5e-28
Identities = 97/336 (28%), Positives = 168/336 (49%), Gaps = 37/336 (11%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVRDY 57
I+VTGGAG+IGSH + E L E ++VV+DNL + ++ + VKF + D+ D
Sbjct: 3 ILVTGGAGYIGSHTLVELLNENREIVVLDNLSNSSEVSLERVKQITGKSVKFYQGDILDR 62
Query: 58 ESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFA 114
+ + +I + + V H A +V E+ ++ T + NV G+I ++ + + N ++F+
Sbjct: 63 DILRKIFAENQIESVIHFAGLKAVGETSENRYVTIKNNVTGSIVLVEEMLKANVNTIVFS 122
Query: 115 SSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHY----CKVFYQLYGVPTVILRYFN 169
SSA VYG+P +PI E P+ +PYG SK E K F QL V+LRYFN
Sbjct: 123 SSATVYGDPQIIPIVESCPVGGTTNPYGTSKYMVERILEDTVKAFPQL---SAVVLRYFN 179
Query: 170 VYGPRQS-------SAYAGVISIFMERALRGE--PLVIFG------DGKQSRDFVYVKDV 214
G +S + + F+ + G+ L +FG DG RD+++V D+
Sbjct: 180 RVGAHESGLIGEDPNGIPNNLMPFISQVAVGKLPQLSVFGGDYNTHDGTGVRDYIHVVDL 239
Query: 215 VEANILVAEKRRAEG--ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRS 272
++ +K + + +N+GTG +++++ + + RPGDI
Sbjct: 240 ALGHLKALDKHQNDAGFHVYNLGTGTGYSVLDMVKAFEAANGITIPYKVVDRRPGDIAVC 299
Query: 273 VADIEK-IKKLGFKPRYSLEEGLLETWKWFKSRTLG 307
+ +K +++LG++ LE+ + +TW W K+ G
Sbjct: 300 YSAPQKALEQLGWETERGLEQMMKDTWNWQKNNPNG 335
>gb|AAA86716.1| (U19895) UDP-glucose 4-epimerase [Neisseria meningitidis]
Length = 339
Score = 125 bits (310), Expect = 8e-28
Identities = 100/335 (29%), Positives = 163/335 (47%), Gaps = 31/335 (9%)
Query: 4 KLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVR 55
K I+VTGG GFIGSH + LK + VV++DNL + +P + + F + D+R
Sbjct: 2 KKILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRLKTITGQEIPFYQGDIR 61
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLI 112
D E + I + D V H A +V ESV +P+ + NV G++ + ++ G K++
Sbjct: 62 DREILRRIFAENRIDSVIHFAGLKAVGESVAEPMKYYDNNVSGSLVLAEEMARAGVFKIV 121
Query: 113 FASSAAVYGEPTSLPIRED-HPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVI-LRYFNV 170
F+SSA VYG+P +P ED P + SPYG SK E + +VI LRYFN
Sbjct: 122 FSSSATVYGDPGKVPYTEDMQPGDTTSPYGTSKSMVERILSDIQKADPRWSVILLRYFNP 181
Query: 171 YGPRQSSAYA----GVIS-----IFMERALRGEPLVIFG------DGKQSRDFVYVKDVV 215
G +S G+ + I A + L +FG DG RD+++V D+
Sbjct: 182 IGAHESGLIGEQPNGIPNNLLPYICQVAAGKLPQLAVFGGDYPTPDGTGMRDYIHVMDLA 241
Query: 216 EANI--LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
E ++ + A+ A N+G+GR ++++E+ S + R GD+
Sbjct: 242 EGHVAAMQAKSNVAGTHLLNLGSGRASSVLEIIRAFEAASGLTIPYEVKPRRAGDLACFY 301
Query: 274 ADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
AD K ++G++ + L + + ++W+W + G
Sbjct: 302 ADPSYAKAQIGWQTQRDLTQMMEDSWRWVSNNPNG 336
>gb|AAD23918.1|AF083467_2 (AF083467) UDP-Glucose 4-epimerase [Neisseria meningitidis]
Length = 339
Score = 125 bits (310), Expect = 8e-28
Identities = 98/335 (29%), Positives = 162/335 (48%), Gaps = 31/335 (9%)
Query: 4 KLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVR 55
K I+VTGG GFIGSH + LK + VV++DNL + +P + + F + D+R
Sbjct: 2 KNILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRLKTITGQEIPFYQGDIR 61
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLI 112
D E + I + D V H A +V ESV +P+ + NV G++ + ++ G ++
Sbjct: 62 DREILRRIFAENRIDSVIHFAGLKAVGESVAEPMKYYDNNVSGSLVLAEEMARAGVFSIV 121
Query: 113 FASSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQL-YGVPTVILRYFNV 170
F+SSA VYG+P +P ED PL + SPYG SK E + ++LRYFN
Sbjct: 122 FSSSATVYGDPGKVPYTEDMPLGDTTSPYGTSKSMVERILTDIQKADPRWSMILLRYFNP 181
Query: 171 YGPRQSSAYA----GVIS-----IFMERALRGEPLVIFG------DGKQSRDFVYVKDVV 215
G +S G+ + I A + L +FG DG RD+++V D+
Sbjct: 182 IGAHESGLIGEQPNGIPNNLLPYICQVAAGKLPQLAVFGDDYPTPDGTGMRDYIHVMDLA 241
Query: 216 EANI--LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
E ++ + A+ A N+G+GR ++++E+ S + R GD+
Sbjct: 242 EGHVAAMQAKSNVAGTHLLNLGSGRASSVLEIIRAFEAASGLTIPFEIKPRRAGDLACFY 301
Query: 274 ADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
AD K ++G++ + L + + ++W+W + G
Sbjct: 302 ADPSYTKAQIGWQTQRDLSQMMEDSWRWVSNNPNG 336
>gb|AAG09980.1|AF248584_1 (AF248584) UDP-glucose 4-epimerase [Moraxella catarrhalis]
Length = 364
Score = 125 bits (310), Expect = 8e-28
Identities = 100/330 (30%), Positives = 158/330 (47%), Gaps = 33/330 (10%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDV-VVIDNLYSGK-------PENVPEGVKFIEADVR 55
K I+VTGGAG+IGSH L + V VV DNL + + V + ++FI+ DV
Sbjct: 25 KKILVTGGAGYIGSHTLIELIQAGFVPVVYDNLSNSSFVAVQRVEQIVGKHIEFIQGDVL 84
Query: 56 DYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLI 112
D + + + + V H A +V ES K+P+ + NV+GT+N+L +++ G +
Sbjct: 85 DKTHLDAVFKAHQFFAVVHFAGLKAVGESTKNPLKYYQNNVVGTLNLLELMAKYGVKNCV 144
Query: 113 FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVI-LRYFNVY 171
F+SSA VYG LPI ED P SPYG SK+ EH + V+ LRYFN
Sbjct: 145 FSSSATVYGSSNRLPITEDMPXFCTSPYGQSKLMVEHILEDLVNADDTWNVVCLRYFNPI 204
Query: 172 GPRQSSAYA-------GVISIFMERALRG--EPLVIFG------DGKQSRDFVYVKDVVE 216
G +S + ++ + G + L +FG DG RD+++V D+ +
Sbjct: 205 GAHESGRIGEDPTDIPNNLMPYISQVAVGNLKQLSVFGNDYETPDGTGVRDYIHVVDLAK 264
Query: 217 ANI-----LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRR 271
++ LV + N+GTG+ T++++L + S + + R GDI
Sbjct: 265 GHVAALHYLVGQSVGIGFCPINLGTGQGTSVLQLIKAFESNTGQSVPYVITSRRTGDIAA 324
Query: 272 SVADIEKIKK-LGFKPRYSLEEGLLETWKW 300
A +K K L + +E ++TW+W
Sbjct: 325 YYASADKAKAILNWTAELDIERMCVDTWRW 354
>pir||S70744 UDPglucose 4-epimerase (EC 5.1.3.2) - Yersinia enterocolitica
>gi|633700|emb|CAA87706.1| (Z47767) Uridine Diphosphate
Glucose Epimerase [Yersinia enterocolitica]
Length = 336
Score = 124 bits (308), Expect = 1e-27
Identities = 105/331 (31%), Positives = 155/331 (46%), Gaps = 29/331 (8%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEGVK-------FIEADVRDY 57
I+VTGGAG+IGSH L E DVVV+DNL + E++ K F + D+ D
Sbjct: 3 ILVTGGAGYIGSHTVLTLLENGEDVVVLDNLSNASAESLLRVSKITGRTPVFYQGDILDR 62
Query: 58 ESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGNGKLIFA 114
+ +I D V H A SV ESV P+ + NV G+I +L + G KLIF+
Sbjct: 63 NCLKKIFFEHKIDSVIHFAGLKSVGESVVKPIEYYQNNVTGSIILLEEMVISGVKKLIFS 122
Query: 115 SSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQLYGVPTV-ILRYFNVYG 172
SSA VYG+P +P+ ED + +PYG SKV E K F Y ++ LRYFN G
Sbjct: 123 SSATVYGDPEFVPLTEDARIGGTTNPYGSSKVMIEQILKDFAFAYPDFSIRALRYFNPVG 182
Query: 173 PRQSSAYA--------GVISIFMERALRGEP-LVIFG------DGKQSRDFVYVKDVVEA 217
S ++ + A+ P L ++G DG RD+++V D+ E
Sbjct: 183 AHISGLIGEDPNGKPNNLLPFITQVAIGKLPKLAVYGNDYPTVDGSGVRDYIHVMDLAEG 242
Query: 218 NILVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIE 277
++ + +N+G+G +++E+ + +S RPGDI A E
Sbjct: 243 HLCALNNLTHGFKVYNLGSGIGHSVLEMIAEFELISGKKIPYEIVARRPGDIAECWASPE 302
Query: 278 -KIKKLGFKPRYSLEEGLLETWKWFKSRTLG 307
K+L +K + +L L W W +S G
Sbjct: 303 LAFKELKWKAKRNLTYMLKHAWNWQQSNPNG 333
>pir||T00467 UDPglucose 4-epimerase homolog F19I3.8 - Arabidopsis thaliana
>gi|3033381|gb|AAC12825.1| (AC004238) putative
UDP-galactose-4-epimerase [Arabidopsis thaliana]
Length = 375
Score = 123 bits (306), Expect = 2e-27
Identities = 106/336 (31%), Positives = 162/336 (47%), Gaps = 44/336 (13%)
Query: 6 IVVTGGAGFIGSHIA-EALKEENDVVVIDNLYSGKPENV---------PEGVKFIEADVR 55
++VTGGAG+IGSH A LK+ V ++DNL G V P ++FI AD+
Sbjct: 40 VLVTGGAGYIGSHAALRLLKDSYRVTIVDNLSRGNLGAVKILQQLFPEPGKLQFIYADLG 99
Query: 56 DYESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS-EGNGKLI 112
D ++ +I S + D V H AA ++ T+ +L ++ G LI
Sbjct: 100 DANAVNKIFSENAFDAVMHFAAVAYYYHNITS----------NTLVVLETMAAHGVKTLI 149
Query: 113 FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
++S+ A YGEP +PI E+ P PI+PYG +K E F + + +ILRYFNV G
Sbjct: 150 YSSTCATYGEPEKMPITEETPQVPINPYGKAKKMAEDIILDFSKNSIMAVMILRYFNVIG 209
Query: 173 ----------PRQSSAYAGVISIFMERALRG--EPLVIFG------DGKQSRDFVYVKDV 214
PR + G IS A RG L I G DG RD++ V D+
Sbjct: 210 SDPEGRLGEAPRPELSEHGRISGACFDAARGIIPGLQIKGTDYKTVDGTCVRDYIDVTDL 269
Query: 215 VEANILVAEKRR-AEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
V+A++ EK + + FNVGTG+ +++ E + + ++ + + R GD
Sbjct: 270 VDAHVKALEKAKPRKVGIFNVGTGKGSSVKEFVEACKKATGVDIKVDYLERRAGDYAEVY 329
Query: 274 ADIEKIK-KLGFKPRY-SLEEGLLETWKWFKSRTLG 307
+D KIK +L + ++ +L+E L W+W K G
Sbjct: 330 SDPRKIKEELNWTAKHTNLQESLKMAWRWQKLHRSG 365
>gb|AAF91338.1|AF248583_1 (AF248583) UDP-glucose 4-epimerase [Moraxella catarrhalis]
Length = 364
Score = 123 bits (306), Expect = 2e-27
Identities = 101/337 (29%), Positives = 160/337 (46%), Gaps = 33/337 (9%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDV-VVIDNLYSGK-------PENVPEGVKFIEADVR 55
K I+VTGGAG+IGSH L + V VV DNL + + V + ++FI+ DV
Sbjct: 25 KKILVTGGAGYIGSHTLIELIQAGFVPVVYDNLSNSSFVAVQRVEQIVGKHIEFIQGDVL 84
Query: 56 DYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLI 112
D + + + + V H A +V ES K+P+ + NV+GT+++L +++ G I
Sbjct: 85 DKTHLDAVFKAHQFFAVVHFAGLKAVGESTKNPLKYYQNNVVGTLSLLELMAKYGVKNCI 144
Query: 113 FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVI-LRYFNVY 171
F+SSA VYG LPI ED P SPYG SK+ EH + V+ LRYFN
Sbjct: 145 FSSSATVYGSSNRLPITEDMPRFCTSPYGQSKLMVEHILEDLVNADDTWNVVCLRYFNPI 204
Query: 172 GPRQSSAYA-------GVISIFMERALRG--EPLVIFG------DGKQSRDFVYVKDVVE 216
G +S + ++ + G + L +FG DG RD+++V D+ +
Sbjct: 205 GAHESGRIGEDPTDIPNNLMPYISQVAVGNLKQLSVFGNDYETPDGTGVRDYIHVVDLAK 264
Query: 217 ANI-----LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRR 271
++ LV + N+GTG+ T++++L + S + + R GDI
Sbjct: 265 GHVAALHYLVGQSVGIGFCPINLGTGQGTSVLQLIKAFESNTGQSVPYVITSRRTGDIAA 324
Query: 272 SVADIEKIKK-LGFKPRYSLEEGLLETWKWFKSRTLG 307
A +K K L + +E ++TW+W + G
Sbjct: 325 YYASADKAKAILNWTAELDIERMCVDTWRWQSNNPKG 361
>pir||C69148 dTDP-glucose 4,6-dehydratase related protein - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621434|gb|AAB84879.1| (AE000823) dTDP-glucose
4,6-dehydratase related protein [Methanobacterium
thermoautotrophicum]
Length = 334
Score = 123 bits (305), Expect = 3e-27
Identities = 100/318 (31%), Positives = 158/318 (49%), Gaps = 28/318 (8%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEE-NDVVVIDNLYSGKPENVPEGVKFIEADVRDYES 59
M + I+VTGGAGFIG+++ L+ ++V+ +D +++ + + ++ ADVR+Y
Sbjct: 22 METQRILVTGGAGFIGTNLVNELRNRGHEVLAVDLMHTERED-------YMRADVREYRQ 74
Query: 60 IAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSA 117
+ I DYV+H AA+ + NVIGT ++LR + ++IF SSA
Sbjct: 75 VERIFEEDKFDYVYHLAAEYGRWNGEDYYENLWKTNVIGTKHMLRMQEKLGFRMIFFSSA 134
Query: 118 AVYGEPTSLPIREDHPLNPIS------PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
VYG+ + L + NPIS Y ++K +GE C +++G TV +R N Y
Sbjct: 135 EVYGDYSGLMSEDVMVKNPISDTYQMNDYAITKWAGELMCMNSAEMFGTETVRVRPVNCY 194
Query: 172 GPRQS-SAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVE--ANILVAEKRRAE 228
GP + S Y G I IF+ AL +P ++ K+ D YV+D V ANI+
Sbjct: 195 GPHEKYSPYKGFIPIFIYHALHRKPYTVYKGHKRIID--YVEDSVRTFANIV---DNFIP 249
Query: 229 GETFNVG--TGRETTIIELAMKIIE-LSSTSSQILFSKPRPGDIRRSVADIEK-IKKLGF 284
GE +NVG T E I E + ++E + S + + + P + D K I+ L
Sbjct: 250 GEVYNVGGRTEWEHDIKEYSDMVLEAVGIDDSIVTYRESEPFTTKVKTMDFSKAIRDLKH 309
Query: 285 KPRYSLEEGLLETWKWFK 302
P+ EEG+ T +W K
Sbjct: 310 DPQVPPEEGIRRTVEWMK 327
>sp|P56997|GALE_NEIMA UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|11270141|pir||F82014 UDPglucose
4-epimerase (EC 5.1.3.2) NMA0203 [similarity] -
Neisseria meningitidis (group A strain Z2491)
>gi|7378972|emb|CAB83517.1| (AL162752) UDP-glucose
4-epimerase [Neisseria meningitidis Z2491]
Length = 339
Score = 123 bits (305), Expect = 3e-27
Identities = 98/335 (29%), Positives = 162/335 (48%), Gaps = 31/335 (9%)
Query: 4 KLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVR 55
K I+VTGG GFIGSH + LK + VV++DNL + +P + + F + D+R
Sbjct: 2 KNILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRLKTITGQEIPFYQGDIR 61
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLI 112
D E + I + D V H A +V ESV +P+ + NV G++ + ++ G ++
Sbjct: 62 DREILRRIFAENRIDSVIHFAGLKAVGESVAEPMKYYDNNVSGSLVLAEEMARAGVFSIV 121
Query: 113 FASSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQL-YGVPTVILRYFNV 170
F+SSA VYG+P +P ED PL + SPYG SK E + ++LRYFN
Sbjct: 122 FSSSATVYGDPGKVPYTEDMPLGDTTSPYGTSKSMVERILTDIQKADPRWSMILLRYFNP 181
Query: 171 YGPRQSSAYA----GVIS-----IFMERALRGEPLVIFG------DGKQSRDFVYVKDVV 215
G +S G+ + I + R L +FG DG RD+++V D+
Sbjct: 182 IGAHESGLIGEQPNGIPNNLLPYICQVASGRLPQLSVFGGDYPTPDGTGMRDYIHVMDLA 241
Query: 216 EANI--LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
E ++ + A+ A N+G+GR ++++E+ S + R GD+
Sbjct: 242 EGHVAAMQAKSNVAGTHLLNLGSGRASSVLEIIRAFEAASGLTIPYEVKPRRAGDLACFY 301
Query: 274 ADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
AD K ++G++ + L + + ++W+W + G
Sbjct: 302 ADPSYTKAQIGWQTQRDLAQMMEDSWRWVSNNPNG 336
>sp|P95780|RMLB_STRMU DTDP-GLUCOSE 4,6-DEHYDRATASE >gi|1813347|dbj|BAA11249.1| (D78182)
dTDP-glucose-4,6-dehydratase [Streptococcus mutans]
Length = 348
Score = 122 bits (302), Expect = 7e-27
Identities = 100/328 (30%), Positives = 157/328 (47%), Gaps = 40/328 (12%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEND---VVVIDNL-YSGKPENVPE----GVKFIEADVR 55
K I+VTGGAGFIGS+ + + V V+D L Y+G N+ E V+ + D+
Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNHANLEEILGDRVELVVGDIA 64
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D E + ++ + AD + H AA+ + S+KDP N +GT +L A + + + S
Sbjct: 65 DSELVDKLAAKADAIVHYAAESHNDNSLKDPSPFIYTNFVGTYTLLEAARKYDIRFHHVS 124
Query: 116 SAAVYGEPTSLPIREDHP---------------LNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED P NP SPY +K + + K + + +GV
Sbjct: 125 TDEVYGD---LPLREDLPGHGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGV 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G+GK RD+++ D
Sbjct: 182 KATISNCSNNYGPYQH------IEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHST 235
Query: 217 ANILVAEKRRAEGETFNVGTGRETTIIELAMKIIE-LSSTSSQILFSKPRPG-DIRRSVA 274
+ K R GET+ +G E E+ I+E +S R G D+R ++
Sbjct: 236 GVWAILTKGRI-GETYLIGADGEKNNKEVLELILEKMSQPKDAYDHVTDRAGHDLRYAID 294
Query: 275 DIEKIKKLGFKPRY-SLEEGLLETWKWF 301
+ ++LG+KP++ + EEGL +T KW+
Sbjct: 295 STKLREELGWKPQFTNFEEGLEDTIKWY 322
>sp|Q59624|GALE_NEIME UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|481842|pir||S39638 UDPglucose
4-epimerase (EC 5.1.3.2) galE NMB0064 [similarity] -
Neisseria meningitidis (strain MC58)
>gi|406095|gb|AAA65535.1| (L20495) UDP-glucose
4-epimerase [Neisseria meningitidis]
>gi|7225285|gb|AAF40532.1| (AE002366) UDP-glucose
4-epimerase [Neisseria meningitidis MC58]
Length = 339
Score = 121 bits (301), Expect = 9e-27
Identities = 97/335 (28%), Positives = 161/335 (47%), Gaps = 31/335 (9%)
Query: 4 KLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVR 55
K I+VTGG GFIGSH + LK + VV++DNL + +P + + F + D+R
Sbjct: 2 KKILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRLKTITGQEIPFYQGDIR 61
Query: 56 DYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLI 112
D E + I + D V H A +V ESV +P+ + NV G++ + ++ G ++
Sbjct: 62 DREILRRIFAENRIDSVIHFAGLKAVGESVAEPMKYYDNNVSGSLVLAEEMARAGVFSIV 121
Query: 113 FASSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQL-YGVPTVILRYFNV 170
F+SSA VYG+P +P ED P + SPYG SK E + ++LRYFN
Sbjct: 122 FSSSATVYGDPGKVPYTEDMPPGDTTSPYGASKSMVERILTDIQKADPRWSMILLRYFNP 181
Query: 171 YGPRQSSAYA----GVIS-----IFMERALRGEPLVIFG------DGKQSRDFVYVKDVV 215
G +S G+ + I A + L +FG DG RD+++V D+
Sbjct: 182 IGAHESGLIGEQPNGIPNNLLPYICQVAAGKLPQLAVFGDDYPTPDGTGMRDYIHVMDLA 241
Query: 216 EANI--LVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
E ++ + A+ A N+G+GR ++++E+ S + R GD+
Sbjct: 242 EGHVAAMQAKSNVAGTHLLNLGSGRASSVLEIIRAFEAASGLTIPYEVKPRRAGDLACFY 301
Query: 274 ADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
AD K ++G++ + L + + ++W+W + G
Sbjct: 302 ADPSYTKAQIGWQTQRDLTQMMEDSWRWVSNNPNG 336
>sp|P40801|GALX_PACTA GAL10 BIFUNCTIONAL PROTEIN [INCLUDES: UDP-GLUCOSE 4-EPIMERASE
(GALACTOWALDENASE); ALDOSE 1-EPIMERASE (MUTAROTASE)]
>gi|322912|pir||S29621 UDPglucose 4-epimerase (EC
5.1.3.2) - yeast (Pachysolen tannophilus)
>gi|3265|emb|CAA48580.1| (X68593) UDP-galactose-
4-epimerase [Pachysolen tannophilus]
Length = 689
Score = 121 bits (300), Expect = 1e-26
Identities = 97/339 (28%), Positives = 159/339 (46%), Gaps = 37/339 (10%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVRDY 57
I+VTGGAG+IGSH + E + +VVV+DNL + + + + + F + D+ D+
Sbjct: 4 ILVTGGAGYIGSHTVVELVNNGYNVVVVDNLVNSSYDVIVRIEVLTRKQIPFFKIDLNDH 63
Query: 58 ESIAEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFA 114
+++ ++ V H AA +V ES K P+ NV G I++L+ + E N K ++F+
Sbjct: 64 DALDQVFKLYPIQAVLHFAALKAVGESTKFPLNYYSNNVGGAISLLKVMEENNVKNIVFS 123
Query: 115 SSAAVYGEPT----SLPIREDHPLNPISPYGVSKVSGEHYCK-VFYQLYGVPTVILRYFN 169
SSA VYG+ T +PI E P P +PYG +K++ E+ + V+ ILRYFN
Sbjct: 124 SSATVYGDATRFENMIPIPEHCPTGPTNPYGETKITIENIIRDVYANDKSWKCAILRYFN 183
Query: 170 VYGPRQSSAYA--------GVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKDV 214
G S ++ + A+ R E L +FG DG RD+++V D+
Sbjct: 184 PIGAHPSGLIGEDPLGIPNNLLPFLAQVAIGRREKLSVFGSDYNSKDGTPIRDYIHVIDL 243
Query: 215 VEA-----NILVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
+ N L K +N+GTG +T+ E+ E R GD+
Sbjct: 244 AKGHIAALNYLFNHKDNGLCREWNLGTGNGSTVFEVFNAFCEAVGKKLPFEVVGRRDGDV 303
Query: 270 RRSVADIEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
A+ ++ +L +K + S+ + + W W G
Sbjct: 304 LNLTANPKRANTELKWKAQLSINDACKDLWNWTTKNPFG 342
>emb|CAB79762.1| (AL161577) nucleotide sugar epimerase-like protein [Arabidopsis
thaliana]
Length = 429
Score = 121 bits (300), Expect = 1e-26
Identities = 97/334 (29%), Positives = 162/334 (48%), Gaps = 42/334 (12%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVVV----IDNLYSGKPENV------PEGVKFIEADVR 55
++VTG GF+GSH++ AL++ D VV +N Y + G+ +E D+
Sbjct: 90 VLVTGATGFVGSHVSLALRKRGDGVVGLDNFNNYYDPSLKRARRSLLSSRGIFVVEGDLN 149
Query: 56 DYESIAEI--VSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGK--L 111
D + +A++ V + +V H AAQ V ++++P N+ G +N+L N + +
Sbjct: 150 DAKLLAKLFDVVAFTHVMHLAAQAGVRYALENPQSYVHSNIAGLVNLLEICKAANPQPAI 209
Query: 112 IFASSAAVYGEPTSLPIRE-DHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
++ASS++VYG +P E D P S Y +K +GE + +YG+ LR+F V
Sbjct: 210 VWASSSSVYGLNEKVPFSESDRTDQPASLYAATKKAGEEITHTYNHIYGLAITGLRFFTV 269
Query: 171 YGP--RQSSAYAGVISIFMERALRGEPLVIFGDGKQ----SRDFVYVKDVVEANILVAE- 223
YGP R AY F L+G+P+ I+ GK +RDF Y+ D+V+ + +
Sbjct: 270 YGPWGRPDMAYFS----FTRNILQGKPITIY-RGKNRVDLARDFTYIDDIVKGCLGSLDS 324
Query: 224 ---------KRR--AEGETFNVGTGRETTIIELAMKIIE--LSSTSSQILFSKPRPGDIR 270
K+R A FN+G T + + + I+E L + + P GD+
Sbjct: 325 SGKSTGSGGKKRGAAPYRIFNLGNTSPVT-VPILVDILEKHLKVKAKRNFVEMPGNGDVP 383
Query: 271 RSVADIEKIK-KLGFKPRYSLEEGLLETWKWFKS 303
+ A+I + + G+KP LE GL + +W+ S
Sbjct: 384 FTHANISSARNEFGYKPTTDLETGLKKFVRWYLS 417
>gb|AAC44971.1| (U09239) dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
Length = 349
Score = 120 bits (299), Expect = 2e-26
Identities = 100/330 (30%), Positives = 155/330 (46%), Gaps = 44/330 (13%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPE----GVKFIEADVR 55
K I+VTGGAGFIGS+ + E + V V+D L Y+G N+ E V+ + D+
Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGNRANIEEILGNRVELVVGDIA 64
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D E + ++ + AD + H AA+ + S+ DP N IGT +L A + + + S
Sbjct: 65 DAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDIRFHHVS 124
Query: 116 SAAVYGEPTSLPIREDHP---------------LNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED P NP SPY +K + + K + + +GV
Sbjct: 125 TDEVYGD---LPLREDLPGHGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGV 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G+GK RD+++ D
Sbjct: 182 KATISNCSNNYGPYQH------IEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHSS 235
Query: 217 ANILVAEKRRAEGETFNVGTGRETT---IIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
++ K + GET+ +G E ++EL +K E+ + R G R
Sbjct: 236 GVWIILTKGQI-GETYLIGADGEKNNKEVLELILK--EMGQAADAYDHVTDRAGHDLRYA 292
Query: 274 ADIEKIK-KLGFKPRY-SLEEGLLETWKWF 301
D K++ +LG+KP + + E GL T KW+
Sbjct: 293 IDASKLRDELGWKPEFTNFEAGLKATIKWY 322
>emb|CAA40568.1| (X57315) UDP-galactose-4-epimerase [Haemophilus influenzae]
Length = 338
Score = 119 bits (296), Expect = 4e-26
Identities = 94/333 (28%), Positives = 162/333 (48%), Gaps = 31/333 (9%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVRDY 57
I+VTGGAG+IGSH + E L +VVV+DNL + P+++ + KF E D+ D
Sbjct: 3 ILVTGGAGYIGSHTVVELLNVGKEVVVLDNLCNSSPKSLERVKQITGKEAKFYEGDILDR 62
Query: 58 ESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
+ +I + + V H A +V ESV+ P NV GT+ +++ + + G +F+
Sbjct: 63 ALLQKIFAENEINSVIHFAGLKAVGESVQKPTEYYMNNVAGTLVLIQEMKKAGVWNFVFS 122
Query: 115 SSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQLY-GVPTVILRYFNVYG 172
SSA VYG+P +PI ED + +PYG SK E + + ILRYFN G
Sbjct: 123 SSATVYGDPKIIPITEDCEVGGTTNPYGTSKYMVEQILRDTAKAEPKFSMTILRYFNPVG 182
Query: 173 PRQS-------SAYAGVISIFMERALRGE--PLVIFG------DGKQSRDFVYVKDVVEA 217
+S + + ++ + G+ L +FG DG RD+++V D+
Sbjct: 183 AHESGLIGEDPNGIPNNLLPYISQVAIGKLAQLSVFGSDYDTHDGTGVRDYIHVVDLAVG 242
Query: 218 NILVAEKRRAEG--ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
++ ++ + +N+GTG +++++ + ++ + + R GDI +D
Sbjct: 243 HLKALQRHENDAGLHIYNLGTGHGYSVLDMVKAFEKANNITIPYKLVERRSGDIATCYSD 302
Query: 276 IE-KIKKLGFKPRYSLEEGLLETWKWFKSRTLG 307
K+LG+ LE+ + +TW W K+ + G
Sbjct: 303 PSLAAKELGWVAERGLEKMMQDTWNWQKNNSKG 335
>gb|AAB39936.1| (U76617) UDP-glucose- 4-epimerase [Pasteurella multocida]
Length = 338
Score = 119 bits (296), Expect = 4e-26
Identities = 95/333 (28%), Positives = 155/333 (46%), Gaps = 31/333 (9%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVRDY 57
I+VTGGAG+IGSH + E L DVVV+DNL + P+++ + VKF + D+ D
Sbjct: 3 ILVTGGAGYIGSHTVVELLNANKDVVVLDNLCNSSPKSLERVAQITGKQVKFYQGDILDT 62
Query: 58 ESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
+ +I + V H A +V ESV+ P NV G++ +++ + + G +F+
Sbjct: 63 ALLQKIFAENQIQSVMHFAGLKAVGESVQKPAEYYMNNVTGSLVLIQEMKKAGVWNFVFS 122
Query: 115 SSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCK-VFYQLYGVPTVILRYFNVYG 172
SSA VYG+P +PI E + +PYG SK E K + ILRYFN G
Sbjct: 123 SSATVYGDPEIIPITESCKVGGTTNPYGTSKFMVEQILKDIAKATPEFSITILRYFNPVG 182
Query: 173 PRQSSAYA--------GVISIFMERALRGEP-LVIFG------DGKQSRDFVYVKDVVEA 217
+S ++ + A+ P L +FG DG RD+++V D+
Sbjct: 183 AHESGLIGEDPNGIPNNLLPYISQVAIGKLPQLSVFGSDYETHDGTGVRDYIHVVDLAIG 242
Query: 218 NILVAEKRRAEG--ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ ++ + +N+GTG +++++ +++ RPGDI +D
Sbjct: 243 QLKALDRHEGDAGLHIYNLGTGSGYSVLDMVKAFEKVNDIKIPYKLVDRRPGDIATCYSD 302
Query: 276 IEKIK-KLGFKPRYSLEEGLLETWKWFKSRTLG 307
K +L + LE+ + +TW W K G
Sbjct: 303 PSLAKTELNWTAARGLEQMMKDTWHWQKKNPKG 335
>sp|P55579|Y4NG_RHISN HYPOTHETICAL 42.8 KD PROTEIN Y4NG >gi|2182542|gb|AAB91786.1|
(AE000087) Y4nG [Rhizobium sp. NGR234]
Length = 396
Score = 119 bits (296), Expect = 4e-26
Identities = 90/324 (27%), Positives = 156/324 (47%), Gaps = 35/324 (10%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEI 63
K +VTGG+G+ G +++ L + V + +L P ++F++ + D ++ +
Sbjct: 50 KTALVTGGSGYFGELLSKQLLRQGTYVRVFDL--NPPGFSHPNLEFLKGTILDRNAVRQA 107
Query: 64 VSSADYVFHEAAQISVEESVKDPVFTEEVNVIGT-INILRALSEGNGKLIFASSAAVYGE 122
+S D VFH AQ+ + + KD ++ VN GT I + +++ G K ++ SS+AV+G
Sbjct: 108 LSGIDKVFHNVAQVPLAKE-KDLFWS--VNCGGTQIIVDESVATGIEKFVYTSSSAVFGA 164
Query: 123 PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYAGV 182
P S P+ E+ NP YG +K++GE CK Q G+ I+R V G + GV
Sbjct: 165 PKSNPVTEETEPNPAEDYGRAKLAGEIICKEAMQRDGLDVAIVRPRTVLGYGRQ----GV 220
Query: 183 ISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRETTI 242
+ I + RG + + G G FV+ D+ A I + + T+N+G T+
Sbjct: 221 VQILFDWVERGLDIPVLGGGNNKYQFVHSDDLASACIAASNVKGF--ATYNIGAAEFGTM 278
Query: 243 IELAMKIIELSSTSSQILFSKPRPGDIRRSVA----------------------DIEKI- 279
EL +I+ + T S+I P + ++A DI K
Sbjct: 279 RELLQVVIKHAETGSRIKSIPMGPTALAANLASALGLSPLGPYHSLMYGRAMYFDISKAQ 338
Query: 280 KKLGFKPRYSLEEGLLETWKWFKS 303
K+LG+ PRYS + ++ET+ W+++
Sbjct: 339 KELGYAPRYSNSQMMIETYNWYQA 362
>gb|AAC38674.1| (AF030359) dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|2804710|gb|AAC38695.1| (AF030363)
dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|2804723|gb|AAC38706.1| (AF030365)
dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|2804729|gb|AAC38711.1| (AF030366)
dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|3320401|gb|AAC38759.1| (AF030373)
dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|3818498|gb|AAC69540.1| (AF057294) Cps23fQ
[Streptococcus pneumoniae] >gi|4200435|gb|AAD10183.1|
(AF026471) Cps2N [Streptococcus pneumoniae]
Length = 349
Score = 119 bits (296), Expect = 4e-26
Identities = 100/330 (30%), Positives = 154/330 (46%), Gaps = 44/330 (13%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPE----GVKFIEADVR 55
K I+VTGGAGFIGS+ + E + V V+D L Y+G N+ E V+ + D+
Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGNRANIEEILGNRVELVVGDIA 64
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D E + ++ + AD + H AA+ + S+ DP N IGT +L A + + + S
Sbjct: 65 DAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDIRFHHVS 124
Query: 116 SAAVYGEPTSLPIREDHP---------------LNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED P NP SPY +K + + K + + +GV
Sbjct: 125 TDEVYGD---LPLREDLPGHGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGV 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G+GK RD+++ D
Sbjct: 182 KATISNCSNNYGPYQH------IEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHSS 235
Query: 217 ANILVAEKRRAEGETFNVGTGRETT---IIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
+ K + GET+ +G E ++EL +K E+ + R G R
Sbjct: 236 GVWTILTKGQI-GETYLIGADGEKNNKEVLELILK--EMGQAADAYDHVTDRAGHDLRYA 292
Query: 274 ADIEKIK-KLGFKPRY-SLEEGLLETWKWF 301
D K++ +LG+KP + + E GL T KW+
Sbjct: 293 IDASKLRDELGWKPEFTNFEAGLKATIKWY 322
>gb|AAC78676.1| (AF094575) dTDP-glucose-4,6-dehydratase Cps19aN [Streptococcus
pneumoniae]
Length = 349
Score = 119 bits (296), Expect = 4e-26
Identities = 100/330 (30%), Positives = 154/330 (46%), Gaps = 44/330 (13%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPE----GVKFIEADVR 55
K I+VTGGAGFIGS+ + E + V V+D L Y+G N+ E V+ + D+
Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGNRANIEEILGNRVELVVGDIA 64
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D E + ++ + AD + H AA+ + S+ DP N IGT +L A + + + S
Sbjct: 65 DAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDIRFHHVS 124
Query: 116 SAAVYGEPTSLPIREDHP---------------LNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED P NP SPY +K + + K + + +GV
Sbjct: 125 TDEVYGD---LPLREDLPGHGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGV 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G+GK RD+++ D
Sbjct: 182 KATISNCSNNYGPYQH------IEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHSS 235
Query: 217 ANILVAEKRRAEGETFNVGTGRETT---IIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
+ K + GET+ +G E ++EL +K E+ + R G R
Sbjct: 236 GVWTILTKGQI-GETYLIGADGEKNNKEVLELILK--EMGQATDAYDHVTDRAGHDLRYA 292
Query: 274 ADIEKIK-KLGFKPRY-SLEEGLLETWKWF 301
D K++ +LG+KP + + E GL T KW+
Sbjct: 293 IDASKLREELGWKPEFTNFEAGLKATIKWY 322
>sp|P24325|GALE_HAEIN UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|1075413|pir||A64063 UDPglucose
4-epimerase (EC 5.1.3.2) - Haemophilus influenzae
(strain Rd KW20) >gi|1573321|gb|AAC22012.1| (U32719)
UDP-glucose 4-epimerase (galE) [Haemophilus influenzae
Rd]
Length = 338
Score = 118 bits (294), Expect = 6e-26
Identities = 94/333 (28%), Positives = 161/333 (48%), Gaps = 31/333 (9%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVP-------EGVKFIEADVRDY 57
I+VTGGAG+IGSH + E L +VVV+DNL + P+++ + KF E D+ D
Sbjct: 3 ILVTGGAGYIGSHTVVELLNVGKEVVVLDNLCNSSPKSLERVKQITGKEAKFYEGDILDR 62
Query: 58 ESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFA 114
+ +I + + V H A +V ESV+ P NV GT+ +++ + + G +F+
Sbjct: 63 ALLQKIFAENEINSVIHFAGLKAVGESVQKPTEYYMNNVAGTLVLIQEMKKAGVWNFVFS 122
Query: 115 SSAAVYGEPTSLPIREDHPL-NPISPYGVSKVSGEHYCKVFYQLY-GVPTVILRYFNVYG 172
SSA VYG+P +PI ED + +PYG SK E + + ILRYFN G
Sbjct: 123 SSATVYGDPKIIPITEDCEVGGTTNPYGTSKYMVEQILRDTAKAEPKFSMTILRYFNPVG 182
Query: 173 PRQS-------SAYAGVISIFMERALRGE--PLVIFG------DGKQSRDFVYVKDVVEA 217
+S + + ++ + G+ L +FG DG RD+++V D+
Sbjct: 183 AHESGLIGEDPNGIPNNLLPYISQVAIGKLAQLSVFGSDYDTHDGTGVRDYIHVVDLAVG 242
Query: 218 NILVAEKRRAEG--ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
++ ++ + +N+GTG +++++ + ++ + + R GDI +D
Sbjct: 243 HLKALQRHENDAGLHIYNLGTGHGYSVLDMVKAFEKANNITIAYKLVERRSGDIATCYSD 302
Query: 276 IE-KIKKLGFKPRYSLEEGLLETWKWFKSRTLG 307
K+LG+ LE+ + +TW W K+ G
Sbjct: 303 PSLAAKELGWVAERGLEKMMQDTWNWQKNNPKG 335
>emb|CAB05932.1| (Z83335) dTDP-glucose 4,6-dehydratase [Streptococcus pneumoniae]
Length = 349
Score = 118 bits (294), Expect = 6e-26
Identities = 100/330 (30%), Positives = 154/330 (46%), Gaps = 44/330 (13%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPE----GVKFIEADVR 55
K I+VTGGAGFIGS+ + E + V V+D L Y+G N+ E V+ + D+
Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGNRANIEEILGNRVELVVGDIA 64
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D E + ++V+ AD + H AA+ + S+ DP N IG +L A + + + S
Sbjct: 65 DAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTNFIGIYTLLEAARKYDIRFHHVS 124
Query: 116 SAAVYGEPTSLPIREDHP---------------LNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED P NP SPY +K + + K + + +GV
Sbjct: 125 TDEVYGD---LPLREDLPGHGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGV 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G+GK RD+++ D
Sbjct: 182 KATISNCSNNYGPYQH------IEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHSS 235
Query: 217 ANILVAEKRRAEGETFNVGTGRETT---IIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
+ K + GET+ +G E ++EL +K E+ + R G R
Sbjct: 236 GVWTILTKGQI-GETYLIGADGEKNNKEVLELILK--EMGQATDAYDHVTDRAGHDLRYA 292
Query: 274 ADIEKIK-KLGFKPRY-SLEEGLLETWKWF 301
D K++ +LG+KP + + E GL T KW+
Sbjct: 293 IDASKLRDELGWKPEFTNFEAGLKATIKWY 322
>emb|CAB65206.1| (AJ007311) RmlB protein [Legionella pneumophila]
Length = 351
Score = 118 bits (294), Expect = 6e-26
Identities = 92/330 (27%), Positives = 151/330 (44%), Gaps = 29/330 (8%)
Query: 1 MRNKL--IVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPEGVK-----F 49
M+N++ ++VTG AGFIGS+ + + + E ++ +D L Y+G N+ E + F
Sbjct: 18 MKNQMNNLLVTGAAGFIGSNFVKFMNDKYPEIKIISLDKLTYAGNKANLSEMAECKNHLF 77
Query: 50 IEADVRDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL--- 104
++ D+ D + ++ D + H AA+ V+ S+ +P E NVIGT +L A
Sbjct: 78 VQGDILDKSLVLSLLREYEIDTLVHFAAESHVDNSIDNPQIFLETNVIGTFTLLEAARIY 137
Query: 105 -------SEGNGKLIFASSAAVYG--EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFY 155
+ + S+ VYG E E + P SPY SK S +H + +Y
Sbjct: 138 WLNERQWDKSKCRFHHVSTDEVYGSLEREEPAFTEKNSYQPNSPYSASKASSDHIVRAYY 197
Query: 156 QLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVV 215
YG+P N YGP Q +I + + P+ ++G+G RD++YV D
Sbjct: 198 HTYGLPVTTSNCSNNYGPNQHK--EKLIPKVVYACVNQLPITVYGNGSNIRDWLYVMDHC 255
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
EA + +K A GE +N+G E + L I ++ + + R G +R D
Sbjct: 256 EAIDTIIQK-GALGEVYNIGGNNELDNLSLIKMICQMMDDLKPMEIVEDRKGHDKRYAID 314
Query: 276 IEKI-KKLGFKPRYSLEEGLLETWKWFKSR 304
KI K+LG+ P+ L T + +R
Sbjct: 315 NSKIQKELGWVPQGDFVHKLSNTVHHYLTR 344
>gb|AAD19915.1| (AF105113) dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
Length = 348
Score = 117 bits (291), Expect = 1e-25
Identities = 99/330 (30%), Positives = 153/330 (46%), Gaps = 44/330 (13%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPE----GVKFIEADVR 55
K I+VTGGAGFIGS+ + + V V+D L Y+G N+ E V+ + D+
Sbjct: 5 KKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGNRANIEEILGDRVELVVGDIA 64
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D + ++ + AD + H AA+ + S+ DP N IGT +L A + + + S
Sbjct: 65 DAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDIRFHHVS 124
Query: 116 SAAVYGEPTSLPIREDHP---------------LNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED P NP SPY +K + + K + + +GV
Sbjct: 125 TDEVYGD---LPLREDLPGHGEGLGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGV 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G+GK RD+++ D
Sbjct: 182 KATISNCSNNYGPYQH------IEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHSS 235
Query: 217 ANILVAEKRRAEGETFNVGTGRETT---IIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
+ K + GET+ +G E ++EL +K E+ + R G R
Sbjct: 236 GVWTILTKGQI-GETYLIGADGEKNNKEVLELILK--EMGQPADAYDHVTDRAGHDLRYA 292
Query: 274 ADIEKIK-KLGFKPRY-SLEEGLLETWKWF 301
D K++ +LG+KP + + E GL ET KW+
Sbjct: 293 IDASKLRDELGWKPEFTNFEAGLKETIKWY 322
>gb|AAC38679.1| (AF030360) dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|2804697|gb|AAC38684.1| (AF030361)
dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|2804704|gb|AAC38690.1| (AF030362)
dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
>gi|2804716|gb|AAC38700.1| (AF030364)
dTDP-glucose-4,6-dehydratase [Streptococcus pneumoniae]
Length = 349
Score = 116 bits (289), Expect = 2e-25
Identities = 99/330 (30%), Positives = 153/330 (46%), Gaps = 44/330 (13%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVPE----GVKFIEADVR 55
K I+VTGGAGFIGS+ + E + V V+D L Y+G N+ E V+ + D+
Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGNRANIEEILGNRVELVVGDIA 64
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D E + ++ + AD + H AA+ + S+ DP N IGT +L A + + + S
Sbjct: 65 DAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDIRFHHVS 124
Query: 116 SAAVYGEPTSLPIRED---------------HPLNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED NP SPY +K + + K + + +GV
Sbjct: 125 TDEVYGD---LPLREDLLGHGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGV 181
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G+GK RD+++ D
Sbjct: 182 KATISNCSNNYGPYQH------IEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHSS 235
Query: 217 ANILVAEKRRAEGETFNVGTGRETT---IIELAMKIIELSSTSSQILFSKPRPGDIRRSV 273
+ K + GET+ +G E ++EL +K E+ + R G R
Sbjct: 236 GVWTILTKGQI-GETYLIGADGEKNNKEVLELILK--EMGQAADAYDHVTDRAGHDLRYA 292
Query: 274 ADIEKIK-KLGFKPRY-SLEEGLLETWKWF 301
D K++ +LG+KP + + E GL T KW+
Sbjct: 293 IDASKLRDELGWKPEFTNFEAGLKATIKWY 322
>gb|AAC35922.1| (AF071085) putative dTDP-glucose-4,6-dehydratase [Enterococcus
faecalis]
Length = 342
Score = 116 bits (289), Expect = 2e-25
Identities = 96/330 (29%), Positives = 158/330 (47%), Gaps = 44/330 (13%)
Query: 4 KLIVVTGGAGFIGSHIAEALKE---ENDVVVIDNL-YSGKPENVP----EGVKFIEADVR 55
K I+VTGGAGFIGS+ + + E V V+D L Y+G +N+ + V+ + D+
Sbjct: 2 KKIIVTGGAGFIGSNFVHYVVKNHPEVHVTVLDKLTYAGNEKNLEGIPSDRVELVVGDIV 61
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
D E + +V+ D V H A + + S+ DP + N+IGT ++ A + N + S
Sbjct: 62 DAELVNRLVAETDAVVHYAXESHNDNSLNDPFPFVQTNLIGTYTLIEACRKNNVRYHHVS 121
Query: 116 SAAVYGEPTSLPIRED---------------HPLNPISPYGVSKVSGEHYCKVFYQLYGV 160
+ VYG+ LP+RED P NP SPY +K + K + + + +
Sbjct: 122 TDEVYGD---LPLREDLPGHGEGEGEKFTAETPYNPSSPYSSTKAGSDLLVKAWVRSFNL 178
Query: 161 PTVILRYFNVYGPRQSSAYAGVISIFMER----ALRGEPLVIFGDGKQSRDFVYVKDVVE 216
I N YGP Q I F+ R L G ++G GK RD+++ D
Sbjct: 179 QATISNCSNNYGPYQH------IEKFIPRQITNVLSGITPKLYGAGKNVRDWIHTNDHSS 232
Query: 217 ANILVAEKRRAEGETFNVGTGRE---TTIIELAMKIIELSSTSSQILFSKPRPG-DIRRS 272
A + K + GET+ +G E T++EL ++++ + + + R G D+R +
Sbjct: 233 AVWAILTKGQI-GETYLIGADGEEDNKTVMELILELMGQPVDAYEHV--NDRVGHDLRYA 289
Query: 273 VADIEKIKKLGFKPRY-SLEEGLLETWKWF 301
+ ++LG++P + + EGL ET KW+
Sbjct: 290 IDSTRLREELGWEPEFTNFREGLAETIKWY 319
>gi|4503891 UDP-galactose-4-epimerase; UDP galactose-4-epimerase;
galactowaldenase [Homo sapiens]
>gi|2494659|sp|Q14376|GALE_HUMAN UDP-GLUCOSE 4-EPIMERASE
(GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE)
>gi|1119217|gb|AAB86498.1| (L41668)
UDP-galactose-4-epimerase [Homo sapiens]
>gi|2947219|gb|AAC39645.1| (AF022382) UDP-galactose 4'
epimerase [Homo sapiens] >gi|1585500|prf||2201313A UDP
galactose 4'-epimerase [Homo sapiens]
Length = 348
Score = 113 bits (280), Expect = 3e-24
Identities = 99/339 (29%), Positives = 155/339 (45%), Gaps = 37/339 (10%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSG------KPENVPE-------GVKFIE 51
++VTGGAG+IGSH + E L+ VVIDN ++ PE++ V+F E
Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64
Query: 52 ADVRDYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGN 108
D+ D ++ + + V H A +V ESV+ P+ VN+ GTI +L + + G
Sbjct: 65 MDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGV 124
Query: 109 GKLIFASSAAVYGEPTSLPIREDHPLNP-ISPYGVSKVSGEHYCKVFYQLYGV-PTVILR 166
L+F+SSA VYG P LP+ E HP +PYG SK E + Q V+LR
Sbjct: 125 KNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNVVLLR 184
Query: 167 YFNVYGPRQSSAYA----GVISIFMERAL-----RGEPLVIFG------DGKQSRDFVYV 211
YFN G S G+ + M R E L +FG DG RD+++V
Sbjct: 185 YFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHV 244
Query: 212 KDVVEANILVAEKRRAE--GETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
D+ + +I K + + +N+GTG +++++ + + S R GD+
Sbjct: 245 VDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDV 304
Query: 270 RRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A+ ++LG+ L+ + W+W K G
Sbjct: 305 AACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSG 343
>pdb|1EK5|A Chain A, Structure Of Human Udp-Galactose 4-Epimerase In Complex
With Nad+ >gi|8569512|pdb|1EK6|A Chain A, Structure Of
Human Udp-Galactose 4-Epimerase Complexed With Nadh And
Udp-Glucose >gi|8569513|pdb|1EK6|B Chain B, Structure Of
Human Udp-Galactose 4-Epimerase Complexed With Nadh And
Udp-Glucose >gi|4581414|emb|CAB40159.1| (AL031295)
dJ886K2.3(GALE (UDP-galactose-4-epimerase)) [Homo
sapiens]
Length = 348
Score = 113 bits (280), Expect = 3e-24
Identities = 99/339 (29%), Positives = 155/339 (45%), Gaps = 37/339 (10%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSG------KPENVPE-------GVKFIE 51
++VTGGAG+IGSH + E L+ VVIDN ++ PE++ V+F E
Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64
Query: 52 ADVRDYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGN 108
D+ D ++ + + V H A +V ESV+ P+ VN+ GTI +L + + G
Sbjct: 65 MDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGV 124
Query: 109 GKLIFASSAAVYGEPTSLPIREDHPLNP-ISPYGVSKVSGEHYCKVFYQLYGV-PTVILR 166
L+F+SSA VYG P LP+ E HP +PYG SK E + Q V+LR
Sbjct: 125 KNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLR 184
Query: 167 YFNVYGPRQSSAYA----GVISIFMERAL-----RGEPLVIFG------DGKQSRDFVYV 211
YFN G S G+ + M R E L +FG DG RD+++V
Sbjct: 185 YFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHV 244
Query: 212 KDVVEANILVAEKRRAE--GETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
D+ + +I K + + +N+GTG +++++ + + S R GD+
Sbjct: 245 VDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDV 304
Query: 270 RRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A+ ++LG+ L+ + W+W K G
Sbjct: 305 AACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSG 343
>gi|11423071 UDP-galactose-4-epimerase [Homo sapiens]
Length = 373
Score = 113 bits (280), Expect = 3e-24
Identities = 99/339 (29%), Positives = 155/339 (45%), Gaps = 37/339 (10%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSG------KPENVPE-------GVKFIE 51
++VTGGAG+IGSH + E L+ VVIDN ++ PE++ V+F E
Sbjct: 30 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 89
Query: 52 ADVRDYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGN 108
D+ D ++ + + V H A +V ESV+ P+ VN+ GTI +L + + G
Sbjct: 90 MDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGV 149
Query: 109 GKLIFASSAAVYGEPTSLPIREDHPLNP-ISPYGVSKVSGEHYCKVFYQLYGV-PTVILR 166
L+F+SSA VYG P LP+ E HP +PYG SK E + Q V+LR
Sbjct: 150 KNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLR 209
Query: 167 YFNVYGPRQSSAYA----GVISIFMERAL-----RGEPLVIFG------DGKQSRDFVYV 211
YFN G S G+ + M R E L +FG DG RD+++V
Sbjct: 210 YFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHV 269
Query: 212 KDVVEANILVAEKRRAE--GETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDI 269
D+ + +I K + + +N+GTG +++++ + + S R GD+
Sbjct: 270 VDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDV 329
Query: 270 RRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
A+ ++LG+ L+ + W+W K G
Sbjct: 330 AACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSG 368
>sp|P37420|RFAD_SALTY ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE (ADP-GLYCEROMANNO-HEPTOSE
6-EPIMERASE) >gi|459160|gb|AAA59064.1| (U06472)
ADP-L-glycero-mannoheptose-6-epimerase [Salmonella
typhimurium]
Length = 310
Score = 110 bits (273), Expect = 2e-23
Identities = 97/314 (30%), Positives = 146/314 (45%), Gaps = 27/314 (8%)
Query: 5 LIVVTGGAGFIGSHIAEALKEEN--DVVVIDNLYSGKPENVPEGVKFIEADVRDY----E 58
+I+VTGGAGFIGS+I +AL ++ D++V+DNL G + V ++ ++ DY +
Sbjct: 1 MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGT-----KFVNLVDLNIADYMDKED 55
Query: 59 SIAEIVSSADY-----VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIF 113
+ +I+S + +FHE A S E D + + N + +L E ++
Sbjct: 56 FLIQIMSGEELGDIEAIFHEGACSSTTEW--DGKYMMDNNYQYSKELLHYCLEREIPFLY 113
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
ASSAA YG TS I P++ YG SK + Y + V RYFNVYGP
Sbjct: 114 ASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGP 173
Query: 174 RQ--SSAYAGVISIFMERALRGE-PLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
R+ + A V + GE P + G RDFVYV DV N+ E +
Sbjct: 174 REGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAAVNLWFLES--GKSG 231
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSS--QILFSKPRPGDIRR-SVADIEKIKKLGF-KP 286
FN+GTGR + +A + S I F G + + AD+ ++ G+ KP
Sbjct: 232 IFNLGTGRAESFQAVADATLAYHKKGSIEYIPFPDKLKGRYQAFTQADLTNLRNAGYDKP 291
Query: 287 RYSLEEGLLETWKW 300
++ EG+ E W
Sbjct: 292 FKTVAEGVTEYMAW 305
>emb|CAA07653.1| (AJ007747) putative nucleotide sugar epimerase/ dehydratase
[Bordetella bronchiseptica]
Length = 313
Score = 110 bits (272), Expect = 2e-23
Identities = 84/265 (31%), Positives = 131/265 (48%), Gaps = 29/265 (10%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVV-IDNLYSGKPENVPE--GVKFIEADVRDYESI 60
K + +TG G IGSHIAE L E D VV IDN +G+ E++ + + F+E + D+ +
Sbjct: 2 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSIADHALV 61
Query: 61 AEIVS--SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFASSA 117
+++ D V H AA + + T N +G N+++A + N G+ ++ +A
Sbjct: 62 NQLIGDLQPDAVVHTAASYKDPDDWYNDTLT---NCVGGSNVVQAAKKNNVGRFVYFQTA 118
Query: 118 AVYG-EPTSLPIREDHPLNPI-SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
YG +P P+R DHP NP S Y +SK + E Y + G+ V R NV GPR
Sbjct: 119 LCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDY----LEYSGLDFVTFRLANVVGPRN 174
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG---ETF 232
S G + IF +R G+ + K RDFV+VKD+ A + R +G +
Sbjct: 175 VS---GPLPIFFQRLSEGKKCFV---TKARRDFVFVKDLARATV-----RAVDGVGHGAY 223
Query: 233 NVGTGRETTIIELAMKIIELSSTSS 257
+ +G + I EL ++E + S
Sbjct: 224 HFSSGTDVAIKELYDAVVEAMALPS 248
>pdb|1EQ2|A Chain A, The Crystal Structure Of Adp-L-Glycero-D-Mannoheptose 6-
Epimerase >gi|11513848|pdb|1EQ2|B Chain B, The Crystal
Structure Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513849|pdb|1EQ2|C Chain C, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513850|pdb|1EQ2|D Chain D, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513851|pdb|1EQ2|E Chain E, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513852|pdb|1EQ2|F Chain F, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513853|pdb|1EQ2|G Chain G, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513854|pdb|1EQ2|H Chain H, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513855|pdb|1EQ2|I Chain I, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
>gi|11513856|pdb|1EQ2|J Chain J, The Crystal Structure
Of Adp-L-Glycero-D-Mannoheptose 6- Epimerase
Length = 310
Score = 110 bits (272), Expect = 2e-23
Identities = 96/316 (30%), Positives = 149/316 (46%), Gaps = 31/316 (9%)
Query: 5 LIVVTGGAGFIGSHIAEALKEEN--DVVVIDNLYSGKPENVPEGVKFIEADVRDY----E 58
+I+VTGGAGFIGS+I +AL ++ D++V+DNL G + V ++ ++ DY +
Sbjct: 1 MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGT-----KFVNLVDLNIADYMDKED 55
Query: 59 SIAEIVSSADY-----VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIF 113
+ +I++ ++ +FHE A S E D + + N + +L E ++
Sbjct: 56 FLIQIMAGEEFGDVEAIFHEGAXSSTTEW--DGKYMMDNNYQYSKELLHYCLEREIPFLY 113
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
ASSAA YG TS I P++ YG SK + Y + V RYFNVYGP
Sbjct: 114 ASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGP 173
Query: 174 RQ--SSAYAGVISIFMERALRGE-PLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
R+ + A V + GE P + G RDFVYV DV + N+ E
Sbjct: 174 REGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLE--NGVSG 231
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRR-----SVADIEKIKKLGF- 284
FN+GTGR + +A + QI + P P ++ + AD+ ++ G+
Sbjct: 232 IFNLGTGRAESFQAVADATLAYHK-KGQIEYI-PFPDKLKGRYQAFTQADLTNLRAAGYD 289
Query: 285 KPRYSLEEGLLETWKW 300
KP ++ EG+ E W
Sbjct: 290 KPFKTVAEGVTEYMAW 305
>sp|P17963|RFAD_ECOLI ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE (ADP-GLYCEROMANNO-HEPTOSE
6-EPIMERASE) >gi|78299|pir||JU0299
ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) rfaD
[validated] - Escherichia coli >gi|41763|emb|CAA38364.1|
(X54492) acidic 34,893Da HtrM protein [Escherichia
coli] >gi|147576|gb|AAA24525.1| (M33577) rfaD protein
[Escherichia coli] >gi|466757|gb|AAB18596.1| (U00039)
ADP-L-Glycero-D-mannoheptose-6-epimerase [Escherichia
coli] >gi|1790049|gb|AAC76643.1| (AE000440)
ADP-L-glycero-D-mannoheptose-6-epimerase [Escherichia
coli K12]
Length = 310
Score = 109 bits (270), Expect = 4e-23
Identities = 96/316 (30%), Positives = 149/316 (46%), Gaps = 31/316 (9%)
Query: 5 LIVVTGGAGFIGSHIAEALKEEN--DVVVIDNLYSGKPENVPEGVKFIEADVRDY----E 58
+I+VTGGAGFIGS+I +AL ++ D++V+DNL G + V ++ ++ DY +
Sbjct: 1 MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGT-----KFVNLVDLNIADYMDKED 55
Query: 59 SIAEIVSSADY-----VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIF 113
+ +I++ ++ +FHE A S E D + + N + +L E ++
Sbjct: 56 FLIQIMAGEEFGDVEAIFHEGACSSTTEW--DGKYMMDNNYQYSKELLHYCLEREIPFLY 113
Query: 114 ASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP 173
ASSAA YG TS I P++ YG SK + Y + V RYFNVYGP
Sbjct: 114 ASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGP 173
Query: 174 RQ--SSAYAGVISIFMERALRGE-PLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
R+ + A V + GE P + G RDFVYV DV + N+ E
Sbjct: 174 REGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLE--NGVSG 231
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRR-----SVADIEKIKKLGF- 284
FN+GTGR + +A + QI + P P ++ + AD+ ++ G+
Sbjct: 232 IFNLGTGRAESFQAVADATLAYHK-KGQIEYI-PFPDKLKGRYQAFTQADLTNLRAAGYD 289
Query: 285 KPRYSLEEGLLETWKW 300
KP ++ EG+ E W
Sbjct: 290 KPFKTVAEGVTEYMAW 305
>sp|P45048|RFAD_HAEIN ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE (ADP-GLYCEROMANNO-HEPTOSE
6-EPIMERASE) >gi|1073827|pir||F64183
ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) HI1114
[similarity] - Haemophilus influenzae (strain Rd KW20)
>gi|1574668|gb|AAC22768.1| (U32791)
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD)
[Haemophilus influenzae Rd]
Length = 308
Score = 109 bits (270), Expect = 4e-23
Identities = 94/321 (29%), Positives = 151/321 (46%), Gaps = 34/321 (10%)
Query: 5 LIVVTGGAGFIGSHIAEALKE--ENDVVVIDNLYSGKPENVPEGVKFIEADVRDY----E 58
+I+VTGGAGFIGS+I +AL + D++V+DNL G + ++ D+ DY +
Sbjct: 1 MIIVTGGAGFIGSNIVKALNDLGRKDILVVDNLKDGT-----KFANLVDLDIADYCDKED 55
Query: 59 SIAEIVSSADY-----VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIF 113
IA I++ ++ VFHE A + E D + N + +L + +
Sbjct: 56 FIASIIAGDEFGDIDAVFHEGACSATTEW--DGKYIMHNNYEYSKELLHYCLDREIPFFY 113
Query: 114 ASSAAVYGEPTSLPIREDHPLN-PISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
ASSAA YG+ + RE+ P++ YG SK + Y + P RYFNVYG
Sbjct: 114 ASSAATYGD--TKVFREEREFEGPLNVYGYSKFLFDQYVRNILPEAKSPVCGFRYFNVYG 171
Query: 173 PRQS--SAYAGVISIFMERALRGE-PLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG 229
PR++ + A V + L+GE P + G RDFVYV DV NI +
Sbjct: 172 PRENHKGSMASVAFHLNNQILKGENPKLFAGSEHFRRDFVYVGDVAAVNIWCWQ--NGIS 229
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRR-----SVADIEKIKKLGF 284
+N+GTG + +A +++ + + P P ++ + AD+ K++ G+
Sbjct: 230 GIYNLGTGNAESFRAVADAVVKFHGKGE--IETIPFPEHLKSRYQEYTQADLTKLRSTGY 287
Query: 285 -KPRYSLEEGLLETWKWFKSR 304
KP ++ EG+ E W +
Sbjct: 288 DKPFKTVAEGVTEYMAWLNRK 308
>gb|AAA98766.1| (L76100) ADP-L-glycero-D-manno-heptose-6-epimerase [Haemophilus
influenzae]
Length = 308
Score = 109 bits (270), Expect = 4e-23
Identities = 94/321 (29%), Positives = 151/321 (46%), Gaps = 34/321 (10%)
Query: 5 LIVVTGGAGFIGSHIAEALKE--ENDVVVIDNLYSGKPENVPEGVKFIEADVRDY----E 58
+I+VTGGAGFIGS+I +AL + D++V+DNL G + ++ D+ DY +
Sbjct: 1 MIIVTGGAGFIGSNIVKALNDLGRKDILVVDNLKDGT-----KFANLVDLDIADYCDKED 55
Query: 59 SIAEIVSSADY-----VFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIF 113
IA I++ ++ VFHE A + E D + N + +L + +
Sbjct: 56 FIASIIAGDEFDDIDAVFHEGACSATTEW--DGKYIMHNNYEYSKELLHYCLDREIPFFY 113
Query: 114 ASSAAVYGEPTSLPIREDHPLN-PISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
ASSAA YG+ + RE+ P++ YG SK + Y + P RYFNVYG
Sbjct: 114 ASSAATYGD--TKVFREEREFEGPLNVYGYSKFLFDQYVRNILPEAKSPVCGFRYFNVYG 171
Query: 173 PRQS--SAYAGVISIFMERALRGE-PLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG 229
PR++ + A V + L+GE P + G RDFVYV DV NI +
Sbjct: 172 PRENHKGSMASVAFHLNNQILKGENPKLFAGSEHFRRDFVYVGDVAAVNIWCWQ--NGIS 229
Query: 230 ETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRR-----SVADIEKIKKLGF 284
+N+GTG + +A +++ + + P P ++ + AD+ K++ G+
Sbjct: 230 GIYNLGTGNAESFRAVADAVVKFHGKGE--IETIPFPEHLKSRYQEYTQADLTKLRSTGY 287
Query: 285 -KPRYSLEEGLLETWKWFKSR 304
KP ++ EG+ E W +
Sbjct: 288 DKPFKTVAEGVAEYMAWLNRK 308
>gb|AAG02361.1|AF210249_20 (AF210249) sugar epimerase BlmG [Streptomyces verticillus]
Length = 325
Score = 108 bits (268), Expect = 7e-23
Identities = 96/319 (30%), Positives = 146/319 (45%), Gaps = 25/319 (7%)
Query: 7 VVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVP-EGVKFIEADVRDYESIAEIVS 65
VVTG GFIGSH+ L + V +L P P E +F+ AD+RD A V+
Sbjct: 5 VVTGAGGFIGSHLVRRLVRDGHRVRGVDLVP--PRYGPGEAQEFVIADLRDAAQAARAVA 62
Query: 66 SADYVFHEAAQ---ISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAVYG- 121
AD VF AA I + + + + +I T I + G ++ SSA VY
Sbjct: 63 GADSVFALAANMGGIGWTHTAPAEILHDNL-LISTHTIEACRAAGVRTTVYTSSACVYPA 121
Query: 122 ----EPTSLPIRED--HPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGP-- 173
EP + P+ ED P P YG K++ E C + + +G+ R +YGP
Sbjct: 122 SLQREPDAAPLAEDPVFPAEPDMEYGWEKLTTEILCGAYRRSHGMDIKTARLHAIYGPLG 181
Query: 174 RQSSAYAGVISIFMERALR-----GEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAE 228
+ A +S+ ++ R GE + ++GDG Q+R + YV D VE I +A R
Sbjct: 182 TYTGPRAKSLSMLCDKVARIPGDEGE-IEVWGDGTQTRSYCYVDDCVEGLIRLA--RSDV 238
Query: 229 GETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKK-LGFKPR 287
E N+G+ I L +I ++ + F+ RP R V+D + ++ LG+ P
Sbjct: 239 AEPVNIGSEERVDIASLVERIAGVAGKKVRCAFAPDRPVGPRGRVSDNTRCRELLGWAPE 298
Query: 288 YSLEEGLLETWKWFKSRTL 306
SL GL T+ W + + L
Sbjct: 299 TSLAAGLERTYPWIERQVL 317
>pir||C70840 probable dehydrogenase - Mycobacterium tuberculosis (strain H37RV)
>gi|2909577|emb|CAA17306.1| (AL021926) gca
[Mycobacterium tuberculosis]
Length = 318
Score = 107 bits (265), Expect = 2e-22
Identities = 91/315 (28%), Positives = 152/315 (47%), Gaps = 24/315 (7%)
Query: 8 VTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKF--IEADVRDYESIAEIVS 65
+TG G +GSH+AE L V +P P ++F E D+ D+ S+ + ++
Sbjct: 5 ITGAGGMMGSHLAEMLLAAGHDVYATYC---RPTIDPSDLQFNGAEVDITDWCSVYDSIA 61
Query: 66 S--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE--GNGKLIFASSAAVYG 121
+ D VFH AAQ S PV T N++GT + AL + K+I A S+A YG
Sbjct: 62 TFRPDAVFHLAAQSYPAVSWARPVETLTTNMVGTAIVFEALRRVRPHAKIIVAGSSAEYG 121
Query: 122 --EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
+P+ +PI E L P+ PYGVSK + + +++ YG+ TV+ R FN GPR+
Sbjct: 122 FVDPSEVPINERRELRPLHPYGVSKAATDMLAYQYHKSYGMHTVVARIFNCTGPRK---V 178
Query: 180 AGVISIFMERA--LRGEP---LVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNV 234
+S F+ R L P + G+ K R V V+D+ A +L+ +K A G +NV
Sbjct: 179 GDALSDFVRRCTWLEHHPEQSAIRVGNLKTKRTIVDVRDLNRALMLMLDKGEA-GADYNV 237
Query: 235 GTGRETTIIELAMKIIELSSTSSQILFSKP---RPGDIRRSVADIEKIKKL-GFKPRYSL 290
G + ++ ++I + P RP D + D K+ + G++ L
Sbjct: 238 GGSIAYEMGDVLKQVIAACKRDDIVPEVDPALLRPTDEKIIYGDCSKLAAITGWQQEICL 297
Query: 291 EEGLLETWKWFKSRT 305
+ + + + +++S++
Sbjct: 298 TQTIADMFDYWRSKS 312
>gb|AAD12165.1| (AF055922) 4-ketoreductase [Streptomyces fradiae]
>gi|5305785|gb|AAD41816.1|AF147703_2 (AF147703)
hypothetical NDP-hexose 4-ketoreductase TylD
[Streptomyces fradiae]
Length = 336
Score = 107 bits (264), Expect = 2e-22
Identities = 93/321 (28%), Positives = 148/321 (45%), Gaps = 27/321 (8%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVVIDNLY-SGKPENVPEGVK-------FIEADVR 55
+ +VVTG GFIGSH AE L VV L+ S +P E + AD+
Sbjct: 10 RTVVVTGALGFIGSHYAERLAALGARVV--GLHRSARPAAGAEPAAPAAGRSCLVRADLC 67
Query: 56 DY----ESIAEIVSSADYVFHEAAQISVEESVKD-PVFTEEVNVIGTINILR-ALSEGNG 109
D + E AD V H A + +D + NV GT ++L A G G
Sbjct: 68 DEAATRRAFQEWAPGADVVIHCAGLDGNAQYKRDHSASVLDANVRGTAHVLNTARDTGAG 127
Query: 110 KLIFASSAAVYGEPTSLPIREDHPLNPISPY-GVSKVSGEHYCKVFYQLYGVP----TVI 164
++ SS VY P P RED + P+ G V + +C++ +L+G
Sbjct: 128 AVVLLSSTEVYCAPRDSPAREDEEIRRYVPHAGNGYVLSKIFCEIMAELHGAEFGSRIFR 187
Query: 165 LRYFNVYGPRQSSA--YAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVA 222
+R NVYGPR + VI + RA GE + I+GDG+Q+R F++V+D+V A + +
Sbjct: 188 VRPGNVYGPRDGNGGTRTRVIPSMVARAAAGETIEIWGDGRQTRSFIHVEDLVNATLRMV 247
Query: 223 EKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKL 282
E + N+G+ E +I++LA ++ I +P D+ +++ +
Sbjct: 248 EADKY--PVMNIGSPEEVSILDLARTVVSAVGGKGGIRTYPDKPSGPPAQRLDLSRMRDV 305
Query: 283 -GFKPRYSLEEGLLETWKWFK 302
G +PR L G+ +T +W++
Sbjct: 306 TGCEPR-PLRVGIEQTIRWYR 325
>emb|CAB92213.1| (AL356592) NAD-dependent dehydratase. [Streptomyces coelicolor
A3(2)]
Length = 346
Score = 106 bits (261), Expect = 4e-22
Identities = 88/316 (27%), Positives = 135/316 (41%), Gaps = 29/316 (9%)
Query: 6 IVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPE-----GVKFIEADVRDYES 59
++VTGGAGF+GSH+ L + +V +DNL +G+ E V G +F+E D+
Sbjct: 20 VLVTGGAGFLGSHLCTRLLDAGAEVDCLDNLSTGRAEKVAHLAGRPGFRFLERDISAPGC 79
Query: 60 IAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAAV 119
+ D V H A S PV + +GT L + + ASS
Sbjct: 80 ADALTGPYDLVLHLAGPASPAARPDRPVEALDAGSLGTRTALSVAGRDGARFLLASSP-- 137
Query: 120 YGEPTSLPIREDHP--LNPISPYGVSKVS---GEHYCKVFYQLYGVPTVILRYFNVYGPR 174
P R D P +P+ P+ + E G I+R F+ YGP
Sbjct: 138 ---PAGPGTRGDAPDDADPVGPHRACAEAVRFAEALVAAHAGANGSNAGIVRLFDGYGPG 194
Query: 175 QSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNV 234
+ AG + +E AL G P+ + GDG + YV D+V+ +LVA R ++
Sbjct: 195 MRTDGAGTPAALIEAALTGRPVTVPGDGSGTYPLCYVDDMVDGVLLVAAGRSV--RPVDI 252
Query: 235 GTGRETTIIELAMKIIELSSTSSQILF------SKPRPGDIRRSVADIEKIKKLGFKPRY 288
G E T E+A +IEL+ + S + F +PRP + +I G+ P
Sbjct: 253 GGDEEPTAAEIARLVIELTGSDSPLAFVEDAGDGRPRPRPVTGFAREI-----FGWLPSV 307
Query: 289 SLEEGLLETWKWFKSR 304
+ ++GL T F+ R
Sbjct: 308 AWQDGLERTVAAFRDR 323
>gb|AAC60774.1| (U46859) Fcl [Yersinia enterocolitica (type 0:8)]
Length = 321
Score = 105 bits (259), Expect = 8e-22
Identities = 83/322 (25%), Positives = 149/322 (45%), Gaps = 37/322 (11%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEI 63
K + V G G +GS I LK +D+ +I + E D+ ++
Sbjct: 4 KRVFVAGHRGMVGSAIVRQLKGRSDIELILKARA-------------ELDLMSQSAVQAF 50
Query: 64 VSSA--DYVFHEAAQIS-VEESVKDPVFTEEVNVIGTINILRALS-EGNGKLIFASSAAV 119
++ D V+ AA++ ++ + P N++ NI+ A G KL+F S+ +
Sbjct: 51 FTAEAIDEVYLAAAKVGGIQANNNYPAEFIYENLMIECNIINAAHMAGIHKLLFLGSSCI 110
Query: 120 YGEPTSLPIREDHPLNPI-----SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG-- 172
Y + P+ E L + PY ++K++G C+ + + Y + N+YG
Sbjct: 111 YPKMADQPMSESTLLTGVLEPTNEPYAIAKIAGIKLCESYNRQYNRDYRSVMPTNLYGEN 170
Query: 173 ----PRQSSAYAGVISIFMERALRGE-PLVIFGDGKQSRDFVYVKDVVEANILVAE---- 223
P S ++ F E +R + ++++G GK R+F++V D+ A+I V E
Sbjct: 171 DNFHPDNSHVIPALLRRFHEAKMRNDNEIIVWGSGKPMREFLHVDDMAAASIYVMELADD 230
Query: 224 ----KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKI 279
+ NVGTG + TI ELA I ++ S +++F +P R + D+ ++
Sbjct: 231 IYAANTQPMLSHINVGTGIDCTIRELAETIAQVVGFSGKLVFDSSKPDGAPRKLMDVSRL 290
Query: 280 KKLGFKPRYSLEEGLLETWKWF 301
KLG++ + SLE+GL T++WF
Sbjct: 291 DKLGWRYQISLEKGLKMTYQWF 312
>prf||2208414C glucose phosphate thymidylate transferase [Streptomyces peucetius]
Length = 291
Score = 105 bits (259), Expect = 8e-22
Identities = 85/284 (29%), Positives = 137/284 (47%), Gaps = 13/284 (4%)
Query: 31 VIDNL-YSGKPENVP-----EGVKFIEADVRDYESIAEIVSSADYVFHEAAQISVEESVK 84
++D+L Y+G P N+ E F+ D+ D + +V+ D + H AA+ V+ SV+
Sbjct: 1 LLDSLTYAGNPANLDPVRGDERFAFVHGDICDAPLVDRLVAEHDQIVHFAAESHVDRSVR 60
Query: 85 D-PVFTEEVNVIGTINIL-RALSEGNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGV 142
P + NV+GT +L AL + S+ VYG E PL+P S Y
Sbjct: 61 SGPRSSCAPNVMGTQTLLDAALRHAPRIFVHISTDEVYGSVDVGASTETDPLHPSSAYAG 120
Query: 143 SKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDG 202
+K S + +++ +G+ I R N YG Q VI F+ L G + ++GDG
Sbjct: 121 TKASSDLLALSYHRTHGLDVRITRCSNNYGTHQHP--EKVIPRFVTTLLSGGRVPLYGDG 178
Query: 203 KQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRETTIIELAMKIIE-LSSTSSQILF 261
R++++V+D V+A LV E + GE +N+G G E + EL +++ + + +
Sbjct: 179 GNLRNWLHVEDHVDAVELVRE-GGSPGEIYNIGGGTELSNKELTALLLDAVGAGWDSVEL 237
Query: 262 SKPRPGDIRRSVADIEKIKK-LGFKPRYSLEEGLLETWKWFKSR 304
R G RR D KI LG++PR + L ET W++ R
Sbjct: 238 VADRKGHDRRYAVDHGKITALLGYRPRRDFRDSLAETVAWYRDR 281
>emb|CAB63301.1| (AJ251712) GDP-L-fucose synthetase [Yersinia pseudotuberculosis]
Length = 321
Score = 105 bits (259), Expect = 8e-22
Identities = 82/325 (25%), Positives = 152/325 (46%), Gaps = 37/325 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M K + + G G +GS I L+ ND+ +I + E D+ ++
Sbjct: 1 MDKKRVFIAGHRGMVGSAIVRQLENRNDIELIIRDRT-------------ELDLMSQSAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS-VEESVKDPVFTEEVNVIGTINILRALS-EGNGKLIFASS 116
+ ++ D ++ AA++ ++ + P N++ NI+ A G KL+F S
Sbjct: 48 QKFFATEKIDEIYLAAAKVGGIQANNNYPAEFIYQNLMIECNIIHAAHLAGIQKLLFLGS 107
Query: 117 AAVYGEPTSLPIREDHPLNPI-----SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ +Y + + P+ E+ L + PY ++K++G C+ + + YG + N+Y
Sbjct: 108 SCIYPKLAAQPMTEEALLTGVLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLY 167
Query: 172 G------PRQSSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAEK 224
G P S ++ F E +R + +V++G GK R+F++V D+ A++ V E
Sbjct: 168 GENDNFHPENSHVIPALLRRFHEAKIRNDKEMVVWGTGKPMREFLHVDDMAAASVHVMEL 227
Query: 225 RRAEGET--------FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADI 276
+T NVGTG + TI ELA + ++ + ++F +P R + D+
Sbjct: 228 SDQIYQTNTQPMLSHINVGTGVDCTIRELAETMAKVVGFTGNLVFDSTKPDGTPRKLMDV 287
Query: 277 EKIKKLGFKPRYSLEEGLLETWKWF 301
++ KLG+ + SLE GL T++WF
Sbjct: 288 SRLAKLGWCYQISLEVGLTMTYQWF 312
>gb|AAC32346.1| (AF061251) fucose synthetase Fcl [Escherichia coli]
Length = 323
Score = 104 bits (256), Expect = 2e-21
Identities = 85/331 (25%), Positives = 147/331 (43%), Gaps = 39/331 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + I + G G +GS I LK+ +DV ++ E ++ D ++
Sbjct: 3 MNKQRIFIAGHQGMVGSAITRRLKQRDDVELVLRTRD-------------ELNLLDSSAV 49
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ SS D V+ AA++ + S F E N++ N++ A + N KL+F
Sbjct: 50 LDFFSSQKIDQVYLAAAKVGGILANSSYPADFIYE-NIMIEANVIHAAHKNNVNKLLFLG 108
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + PI ED L P + PY ++K++G C+ + + +G + N+
Sbjct: 109 SSCIYPKLAHQPIMEDELLQGKLEPTNEPYAIAKIAGIKLCESYNRQFGRDYRSVMPTNL 168
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F + P +V++G G R+F++V D+ A+I V E
Sbjct: 169 YGPNDNFHPSNSHVIPALLRRFHDAVENNSPNVVVWGSGTPKREFLHVDDMASASIYVME 228
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ N+GTG + TI ELA I ++ I F +P R + D
Sbjct: 229 MPYDIWQKNTKVMLSHINIGTGIDCTICELAETIAKVVGYKGHITFDTTKPDGAPRKLLD 288
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWFKSRTL 306
+ + +LG+ + +L +GL T+ WF L
Sbjct: 289 VTLLHQLGWNHKITLHKGLENTYNWFLENQL 319
>dbj|BAA77731.1| (AB008676) GDP-L-fucose pathway enzyme [Escherichia coli]
Length = 321
Score = 104 bits (256), Expect = 2e-21
Identities = 85/331 (25%), Positives = 147/331 (43%), Gaps = 39/331 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + I + G G +GS I LK+ +DV ++ E ++ D ++
Sbjct: 1 MNKQRIFIAGHQGMVGSAITRRLKQRDDVELVLRTRD-------------ELNLLDSSAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ SS D V+ AA++ + S F E N++ N++ A + N KL+F
Sbjct: 48 LDFFSSQKIDQVYLAAAKVGGILANSSYPADFIYE-NIMIEANVIHAAHKNNVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + PI ED L P + PY ++K++G C+ + + +G + N+
Sbjct: 107 SSCIYPKLAHQPIMEDELLQGKLEPTNEPYAIAKIAGIKLCESYNRQFGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F + P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPNDNFHPSNSHVIPALLRRFHDAVENNSPNVVVWGSGTPKREFLHVDDMASASIYVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ N+GTG + TI ELA I ++ I F +P R + D
Sbjct: 227 MPYDIWQKNTKVMLSHINIGTGIDCTICELAETIAKVVGYKGHITFDTTKPDGAPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWFKSRTL 306
+ + +LG+ + +L +GL T+ WF L
Sbjct: 287 VTLLHQLGWNHKITLHKGLENTYNWFLENQL 317
>sp|P18645|GALE_RAT UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE) >gi|112468|pir||S11223 UDPglucose
4-epimerase (EC 5.1.3.2) - rat >gi|57792|emb|CAA37897.1|
(X53949) UDP-galactose 4-epimerase (AA 1-347) [Rattus
sp.]
Length = 347
Score = 102 bits (253), Expect = 4e-21
Identities = 95/341 (27%), Positives = 156/341 (44%), Gaps = 42/341 (12%)
Query: 6 IVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSG--KPENVPE-----------GVKFIE 51
++VTGGAG+IGSH + E L+ VVIDN ++ +++PE V+F E
Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNSIRGEDSMPESLRRVQELTGRSVEFEE 64
Query: 52 ADVRDYESIAEIVSSADY--VFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL-SEGN 108
D+ D ++ + ++ V H A +V ESV+ P+ VN+ GTI +L + + G
Sbjct: 65 MDILDQAALQHLFKKHNFKAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMRAMGV 124
Query: 109 GKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPT----VI 164
L+F+SSA VYG+P R PYG SK E ++ L T V+
Sbjct: 125 KSLVFSSSATVYGKPVPASGRGPPHRGCTKPYGKSKFFIE---EMIQDLCRADTAWNAVL 181
Query: 165 LRYFNVYGPRQSSAYA----GVISIFMERAL-----RGEPLVIFG------DGKQSRDFV 209
LRYF G +S+ G+ + M R E L +FG DG RD++
Sbjct: 182 LRYFIPIGAHRSARIGEDPQGIPNNLMPYVSQVAIGRREALNVFGDDYATEDGTGVRDYI 241
Query: 210 YVKDVVEANILVAEKRRAE--GETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPG 267
+V D+ + +I +K + + +N+GTG +++++ + + S R G
Sbjct: 242 HVVDLAKGHIAALKKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREG 301
Query: 268 DIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRTLG 307
D+ A+ ++LG+ L+ + W+W K G
Sbjct: 302 DVAACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSG 342
>pir||C64627 ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) HP0859
[similarity] - Helicobacter pylori (strain 26695)
>gi|2313991|gb|AAD07905.1| (AE000596)
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD)
[Helicobacter pylori 26695]
Length = 330
Score = 100 bits (246), Expect = 3e-20
Identities = 90/314 (28%), Positives = 151/314 (47%), Gaps = 27/314 (8%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEEN---DVVVID-----NLYSGK-PENVPE-----G 46
+ N+ I++TGGAGF+GS++A +E + V+++D L+S K P ++ G
Sbjct: 8 LENQTILITGGAGFVGSNLAFYFQENHPKAKVIILDKFRSNTLFSNKRPSSLGHFKNLIG 67
Query: 47 VK--FIEADVRDYESIAEIVS-SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA 103
K I AD+ + + + DY+FH+AA + ++ D + N +N+L
Sbjct: 68 FKGEVIAADINNPLDLRRLEKLHFDYLFHQAA--VSDTTMLDQELVMKTNYQAFLNLLEI 125
Query: 104 LSEGNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTV 163
K+I+ASSA VYG T P +P + YG SK+ + + V V
Sbjct: 126 ARSKKAKVIYASSAGVYGN-TKAPNVVGSNESPENVYGFSKLCMDEF--VLSHSNDNVQV 182
Query: 164 ILRYFNVYGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILV 221
LRYFNVYGPR+ A ++ A+ + + +F G+Q RDFVY++DV++A++
Sbjct: 183 GLRYFNVYGPREFYKEKTASMVLQLALGAMAFKEVKLFEFGEQLRDFVYIEDVIQASVKA 242
Query: 222 AEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIE-KIK 280
+ +++ +NVG + + E+ + E P + + A IE I
Sbjct: 243 MKAQKS--GVYNVGYSQARSYNEIVSILKEHLGDFKVSYIKNPYAFFQKHTQAHIEPAIL 300
Query: 281 KLGFKPRYSLEEGL 294
L + P Y LE G+
Sbjct: 301 DLDYTPLYDLESGI 314
>gb|AAB66900.1| (AF013592) ADP-L-glycero-D-mannoheptose-6-epimerase [Helicobacter
pylori]
Length = 330
Score = 99.5 bits (244), Expect = 4e-20
Identities = 87/314 (27%), Positives = 149/314 (46%), Gaps = 27/314 (8%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEEND---VVVIDNLYSGK--PENVPEGV-------- 47
+ N+ I++TGGAGF GS++A +E + V+++D S N P +
Sbjct: 8 LENQTILITGGAGFDGSNLAFYFQENHPKAKVIILDKFRSNTLFSNNRPSSLGHFKNLIG 67
Query: 48 ---KFIEADVRDYESIAEIVS-SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA 103
+ I AD+ + + + DY+FH+AA + ++ D + N +N+L
Sbjct: 68 FKGEVIAADINNPLDLRRLEKLHFDYLFHQAAVS--DTTMLDQELVMKTNYQAFLNLLEI 125
Query: 104 LSEGNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTV 163
K+I+ASSA VYG T P +P + YG S++ + + + F+ + V
Sbjct: 126 ARSKKAKVIYASSAGVYGN-TKAPNVVGSNESPENVYGFSQLCMDEFVR-FHSNDNIQ-V 182
Query: 164 ILRYFNVYGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILV 221
LRYFNVYGPR+ A ++ A+ + + +F G+Q RDFVY++DV++AN+
Sbjct: 183 GLRYFNVYGPREFYKEKTASMVLQLALSAMAFKEVKLFEFGEQLRDFVYIEDVIQANVKA 242
Query: 222 AEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIE-KIK 280
+ +++ +NVG + + E+ + E P + + A IE I
Sbjct: 243 MKAQKS--GVYNVGYSQARSYNEIVGILKEHLGDFKVSYIKNPYAFFQKHTQAHIEPAIL 300
Query: 281 KLGFKPRYSLEEGL 294
L + P Y LE G+
Sbjct: 301 DLDYTPLYDLESGI 314
>sp|P32055|FCL_ECOLI FUCOSE SYNTHETASE >gi|7429918|pir||C64971 hypothetical 36.1 kD
protein in cpsB 5'region - Escherichia coli (strain
K-12) >gi|8569682|pdb|1GFS|A Chain A, Gdp-Fucose
Synthetase From E. Coli >gi|5821909|pdb|1BSV|A Chain A,
Gdp-Fucose Synthetase From Escherichia Coli Complex With
Nadph >gi|5822075|pdb|1FXS|A Chain A, Gdp-Fucose
Synthetase From Escherichia Coli Complex With Nadp
>gi|1736758|dbj|BAA15908.1| (D90843) Nodulation protein
NolK. [Escherichia coli] >gi|1788365|gb|AAC75113.1|
(AE000295) putative nucleotide di-P-sugar epimerase or
dehydratase [Escherichia coli K12]
Length = 321
Score = 99.1 bits (243), Expect = 6e-20
Identities = 82/326 (25%), Positives = 148/326 (45%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + + + G G +GS I L++ DV ++ E ++ D ++
Sbjct: 1 MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRD-------------ELNLLDSRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ +S D V+ AA++ V + F + N++ NI+ A + + KL+F
Sbjct: 48 HDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ-NMMIESNIIHAAHQNDVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + P+ E L P + PY ++K++G C+ + + YG + N+
Sbjct: 107 SSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F E + P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ NVGTG + TI ELA I ++ +++F +P R + D
Sbjct: 227 LAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLASTYQWF 312
>pdb|1E6U|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reductase
Length = 321
Score = 98.7 bits (242), Expect = 8e-20
Identities = 82/326 (25%), Positives = 150/326 (45%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + + + G G +GS I L++ DV ++ E ++ D ++
Sbjct: 1 MAKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRD-------------ELNLLDSRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ +S D V+ AA++ V + F + N++ NI+ A + + KL+F
Sbjct: 48 HDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ-NMMIESNIIHAAHQNDVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + P+ E L P + PY ++K++G C+ + + YG + N+
Sbjct: 107 SSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQS--SAYAGVISIFMER-----ALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP + + + VI + R A + +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPSNSHVIPALLRRFHEATAQKAPDVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ NVGTG + TI ELA I ++ +++F +P R + D
Sbjct: 227 LAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLASTYQWF 312
>pir||D71887 ADPglyceromanno-heptose 6-epimerase (EC 5.1.3.20) gmhD homolog
[similarity] - Helicobacter pylori (strain J99)
>gi|4155357|gb|AAD06369.1| (AE001509)
ADP-L-GLYCERO-D-MANNOHEPTOSE-6-EPIMERASE [Helicobacter
pylori J99]
Length = 329
Score = 97.9 bits (240), Expect = 1e-19
Identities = 88/315 (27%), Positives = 147/315 (45%), Gaps = 30/315 (9%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEEND---VVVIDNLYSG--KPENVPEGV-------- 47
+ N+ I++TGGAGF+GS++A +E + VVV+D S N P +
Sbjct: 8 LENQTILITGGAGFVGSNLAFYFQENHPKAKVVVLDKFRSNTLSSNNRPSSLGHFKNLIG 67
Query: 48 ---KFIEADVRDYESIAEIVS-SADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRA 103
+ I AD+ + + + DY+FH+AA + ++ + + N +N+L
Sbjct: 68 FKGEVIIADINNPLDLRRLEKLHFDYLFHQAAVS--DTTMLNQELVMKTNYQAFLNLLEI 125
Query: 104 LSEGNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTV 163
K+I+ASSA VYG T P +P + YG SK+ + F + V
Sbjct: 126 ARSKKAKVIYASSAGVYGN-TKAPNIVGSNESPENVYGFSKLCMDE----FVLSHSSDNV 180
Query: 164 I-LRYFNVYGPRQ--SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANIL 220
+ LRYFNVYG R+ A ++ A+ + + +F G+Q RDFVY++DV++AN+
Sbjct: 181 VGLRYFNVYGSREFYKEKTASMVLQLALSAMAFKEVKLFEFGEQLRDFVYIEDVIQANVK 240
Query: 221 VAEKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIE-KI 279
+ +++ +NVG + + E+ + E P + + A IE I
Sbjct: 241 AMKAQKS--GVYNVGYSQARSYNEIVSILKEHLGDFKVSYIKNPYTFFQKHTQAHIEPTI 298
Query: 280 KKLGFKPRYSLEEGL 294
L + P Y LE G+
Sbjct: 299 LDLDYTPLYDLESGI 313
>pdb|1BWS|A Chain A, Crystal Structure Of Gdp-4-Keto-6-Deoxy-D-Mannose
EpimeraseREDUCTASE FROM ESCHERICHIA COLI A KEY ENZYME IN
The Biosynthesis Of Gdp-L-Fucose
Length = 321
Score = 97.9 bits (240), Expect = 1e-19
Identities = 81/326 (24%), Positives = 148/326 (44%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + + + G G +GS I L++ DV ++ E ++ D ++
Sbjct: 1 MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRD-------------ELNLLDSRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ +S D V+ AA++ V + F + N++ NI+ A + + KL+F
Sbjct: 48 HDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ-NMMIESNIIHAAHQNDVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + P+ E L P + PY ++K++G C+ + + YG + N+
Sbjct: 107 SSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F E + P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ NVGTG + TI +LA I ++ +++F +P R + D
Sbjct: 227 LAHEVWLENTQPMLSHINVGTGVDCTIRDLAQTIAKVVGYKGRVVFDASKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLASTYQWF 312
>gb|AAG24814.1| (AF285085) GDP-L-fucose synthetase [Salmonella typhimurium]
Length = 321
Score = 97.9 bits (240), Expect = 1e-19
Identities = 88/326 (26%), Positives = 144/326 (43%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + I V G G +GS I L + DV ++ E D+ D ++
Sbjct: 1 MNKQRIFVAGHRGMVGSAIVRQLAQRGDVELVLRTRD-------------ELDLLDGRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGNGK-LIFAS 115
+ A D V+ AA++ V + F E N++ NI+ A N L+F
Sbjct: 48 QAFFAGAGIDQVYLAAAKVGGIVANNTYPADFIYE-NMMIESNIIHAAHLHNVNILLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y P+ E L P + PY ++K++G C+ + + YG + N+
Sbjct: 107 SSCIYPILARQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F E A P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPDNSHVIPALLRRFHEAAQSHAPEVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 KRRAEGET--------FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
R + NVGTG + TI ELA I ++ +++F +P R + D
Sbjct: 227 LAREVWQENTAPMLSHINVGTGVDCTIRELAQTIAKVVGYQGRVVFDAAKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLAGTYQWF 312
>pdb|1E7Q|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reductase S107a
Length = 321
Score = 97.9 bits (240), Expect = 1e-19
Identities = 81/326 (24%), Positives = 148/326 (44%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + + + G G +GS I L++ DV ++ E ++ D ++
Sbjct: 1 MAKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRD-------------ELNLLDSRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ +S D V+ AA++ V + F + N++ NI+ A + + KL+F
Sbjct: 48 HDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ-NMMIESNIIHAAHQNDVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
++ +Y + P+ E L P + PY ++K++G C+ + + YG + N+
Sbjct: 107 ASCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F E + P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPSNSHVIPALLRRFHEATAQSAPDVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ NVGTG + TI ELA I ++ +++F +P R + D
Sbjct: 227 LAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLASTYQWF 312
>pdb|1E7S|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reductase K140r
Length = 321
Score = 97.9 bits (240), Expect = 1e-19
Identities = 81/326 (24%), Positives = 148/326 (44%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + + + G G +GS I L++ DV ++ E ++ D ++
Sbjct: 1 MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRD-------------ELNLLDSRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ +S D V+ AA++ V + F + N++ NI+ A + + KL+F
Sbjct: 48 HDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ-NMMIESNIIHAAHQNDVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + P+ E L P + PY +++++G C+ + + YG + N+
Sbjct: 107 SSCIYPKLAKQPMAESELLQGTLEPTNEPYAIARIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F E + P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPSNSHVIPALLRRFHEATAQSAPDVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ NVGTG + TI ELA I ++ +++F +P R + D
Sbjct: 227 LAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLASTYQWF 312
>pir||T15370 hypothetical protein C01F1.3 - Caenorhabditis elegans
>gi|1330395|gb|AAB00715.1| (U58761) coded for by C.
elegans cDNA yk62h9.5; coded for by C. elegans cDNA
yk62h9.3; similarity to DTDP-glucose 4,6-Dehydratases
[Caenorhabditis elegans]
Length = 631
Score = 97.5 bits (239), Expect = 2e-19
Identities = 95/323 (29%), Positives = 146/323 (44%), Gaps = 35/323 (10%)
Query: 4 KLIVVTGGAGFIGS----HIAEALKEENDVVVIDNLYSGKPENVPEGV------KFIEAD 53
K +V+TGG GFIGS +I +A N V + + + +NV E V K + D
Sbjct: 6 KNVVITGGCGFIGSNFVNYIHDAWPTCNFVNIDKLILNSDTQNVAESVRNSPRYKLVLTD 65
Query: 54 VRDYESIAEIV--SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKL 111
+++ +I + + D V H AA + + + NV+ I L + GK+
Sbjct: 66 IKNEAAILNVFEQNEIDTVIHFAADCTSTRCYNETAEAVQNNVLSFIQFLETVRT-YGKI 124
Query: 112 ---IFASSAAVYGEPTSLPIREDHPLN-----PISPYGVSKVSGEHYCKVFYQLYGVPTV 163
+ S+ VYG+ + L E + P +PY +K++GE Y + + Y +P V
Sbjct: 125 KRFVHISTDEVYGD-SDLSENEQGKVEFSRLVPGNPYAATKIAGEAYVRAYQTQYNLPIV 183
Query: 164 ILRYFNVYGPRQSSAYAGVISIFMERA-LRGEPLVIFGDGKQSRDFVYVKDVVEANILVA 222
R N+YGP Q V+ F+E A +RGE I G GKQ R +++V D V
Sbjct: 184 TARMNNIYGPNQWD--VKVVPRFIEIAKVRGE-YTIQGSGKQLRSWLFVDDASAGLKAVC 240
Query: 223 EKRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKP-------RPGDIRRSVAD 275
EK E +N+GT E + +LA I E P RP + R +
Sbjct: 241 EKGELH-EIYNLGTYYEKNVADLAKTIQEEVDLQLGRAHEPPKYKSIPDRPYNDLRYLIS 299
Query: 276 IEKIKK-LGFKPRYSLEEGLLET 297
IEK K LG++P S ++G+ T
Sbjct: 300 IEKAKNDLGWEPTTSFDDGMRHT 322
>pir||D55239 cpsB 5'-region hypothetical protein 2 - Escherichia coli
>gi|1407613|gb|AAC77843.1| (U38473) GDP-L-fucose
synthetase [Escherichia coli]
Length = 321
Score = 96.7 bits (237), Expect = 3e-19
Identities = 80/326 (24%), Positives = 148/326 (44%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + + + G G +GS I L++ DV ++ E ++ D ++
Sbjct: 1 MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRD-------------ELNLLDSRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ +S D V+ AA++ V + F + N++ NI+ A + + KL+F
Sbjct: 48 HDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ-NMMIESNIIHAAHQNDVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + P+ E L P + PY ++K++G C+ + + YG + N+
Sbjct: 107 SSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F E + P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ NVGTG + TI ++A I ++ +++F +P R + D
Sbjct: 227 LAHEVWLENTQPMLSHINVGTGVDCTIRDVAQTIAKVVGYKGRVVFDASKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLASTYQWF 312
>gb|AAC73015.1| (AC005824) putative dTDP-glucose 4-6-dehydratase [Arabidopsis
thaliana]
Length = 389
Score = 96.7 bits (237), Expect = 3e-19
Identities = 98/357 (27%), Positives = 157/357 (43%), Gaps = 59/357 (16%)
Query: 6 IVVTGGAGFIGSHIAEALKEE--NDVVVIDNLYSGKPENVPEG--------VKFIEADVR 55
I + G GFIGSH+ E L E + V+ +D +Y+ K +++ E ++F +++
Sbjct: 20 ICMIGAGGFIGSHLCEKLLTETPHKVLALD-VYNDKIKHLLEPDTVEWSGRIQFHRINIK 78
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
+ +V AD + + AA + + P+ T N I + +++ SE N +LI S
Sbjct: 79 HDSRLEGLVKMADLIINLAAICTPADYNTRPLDTIYSNFIDALPVVKYCSENNKRLIHFS 138
Query: 116 SAAVYGEPTSLPIREDHPL----------NPISP------------YGVSKVSGEHYCKV 153
+ VYG+ + +DHPL ISP Y +K E
Sbjct: 139 TCEVYGKTIGSFLPKDHPLRDDPAFYVLKEDISPCIFGSIEKQRWSYACAKQLIERLVYA 198
Query: 154 FYQLYGVPTVILRYFNVYGPRQ---------SSAYAGVISIFMERALRGEPLVIFGDGKQ 204
G+ I+R FN GPR S V++ F LR EPL + G+
Sbjct: 199 EGAENGLEFTIVRPFNWIGPRMDFIPGIDGPSEGVPRVLACFSNNLLRREPLKLVDGGES 258
Query: 205 SRDFVYVKDVVEANILVAEK-RRAEGETFNVGT-GRETTIIELAMKIIEL-SSTSSQILF 261
R FVY+ D +EA +L+ E RA G FNVG E T+ +LA + E+ + S +
Sbjct: 259 QRTFVYINDAIEAVLLMIENPERANGHIFNVGNPNNEVTVRQLAEMMTEVYAKVSGEGAI 318
Query: 262 SKPRP------------GDIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
P D + + D+ I ++LG+ P+ SL + LLE+ ++ RT
Sbjct: 319 ESPTVDVSSKEFYGEGYDDSDKRIPDMTIINRQLGWNPKTSLWD-LLESTLTYQHRT 374
>gb|AAD10233.1| (U72147) unknown [Anabaena sp. CA]
Length = 287
Score = 96.0 bits (235), Expect = 5e-19
Identities = 80/295 (27%), Positives = 136/295 (45%), Gaps = 28/295 (9%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
++NK I+VTGGAGF+G + E L + +G + + E D+R +E+
Sbjct: 6 LQNKRILVTGGAGFLGRQVIEQLGK-----------AGADQAKITIPRSRELDLRVWENC 54
Query: 61 AEIVSSADYVFHEAAQ---ISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSA 117
V D V H AA I + +F + + ++GT I A G K + +
Sbjct: 55 QRAVDQQDIVIHLAAHVGGIGLNREKPAELFYDNL-IMGTQLIHAAYQAGVEKFVCVGTI 113
Query: 118 AVYGEPTSLPIRED-----HPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
Y + T +P +ED +P +PYGV+K + + + Q YG V L N+YG
Sbjct: 114 CAYPKFTPVPFKEDDLWNGYPEETNAPYGVAKKALLVQLQSYRQQYGFNGVYLLPVNLYG 173
Query: 173 PRQS----SAY---AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKR 225
P + S++ A + + + + + L ++GDG +R+F+Y +D I++ +
Sbjct: 174 PEDNFDPGSSHVIPALIHKVHAAQINKVKQLPVWGDGSPTREFLYSEDAAR-GIVMGTQF 232
Query: 226 RAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK 280
+ E N+GTG E +I +L I EL +I++ +P R D E+ K
Sbjct: 233 YNDSEPVNLGTGSEISIRDLVTLICELMEFDGEIVWETDKPNGQPRRCLDTERAK 287
>gb|AAF18254.1|AC011438_16 (AC011438) T23G18.6 [Arabidopsis thaliana]
Length = 389
Score = 95.6 bits (234), Expect = 7e-19
Identities = 96/357 (26%), Positives = 156/357 (42%), Gaps = 59/357 (16%)
Query: 6 IVVTGGAGFIGSHIAEALKEE--NDVVVIDNLYSGKPENVPEG--------VKFIEADVR 55
I + G GFIGSH+ E L E + V+ +D +Y+ K +++ E ++F +++
Sbjct: 20 ICMIGAGGFIGSHLCEKLMTETPHKVLALD-VYNDKIKHLLEPDTVQWAGRIQFHRINIK 78
Query: 56 DYESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFAS 115
+ ++ AD + AA + + P+ T N I + +++ SE N +LI S
Sbjct: 79 HDSRLEGLIKMADLTINLAAICTPADYNTRPLDTIYSNFIDALPVVKYCSENNKRLIHFS 138
Query: 116 SAAVYGEPTSLPIREDHPLNP----------ISP------------YGVSKVSGEHYCKV 153
+ VYG+ + +DHPL ISP Y +K E
Sbjct: 139 TCEVYGKTIGSFLPKDHPLRQDPEFYVLKEDISPCIFGSIEKQRWSYACAKQLIERLVYA 198
Query: 154 FYQLYGVPTVILRYFNVYGPRQ---------SSAYAGVISIFMERALRGEPLVIFGDGKQ 204
G+ I+R FN GPR S V++ F LR EPL + G+
Sbjct: 199 EGAENGLEFTIVRPFNWIGPRMDFIPGIDGPSEGVPRVLACFSNNLLRREPLKLVDGGES 258
Query: 205 SRDFVYVKDVVEANILVAEK-RRAEGETFNVGT-GRETTIIELAMKIIEL-SSTSSQILF 261
R F+Y+KD +EA +L+ E RA G FNVG E T+ +LA + E+ + S +
Sbjct: 259 QRTFIYIKDAIEAVLLMIENPERANGHIFNVGNPNNEVTVRQLAEMMTEVYAKVSGETAI 318
Query: 262 SKPR------------PGDIRRSVADIEKI-KKLGFKPRYSLEEGLLETWKWFKSRT 305
P D + + D+ I ++LG+ P+ SL + LLE+ ++ T
Sbjct: 319 ESPTIDVSSKEFYGEGYDDSDKRIPDMTIINRQLGWNPKTSLWD-LLESTLTYQHTT 374
>pdb|1E7R|A Chain A, Gdp 4-Keto-6-Deoxy-D-Mannose Epimerase Reductase Y136e
Length = 321
Score = 95.6 bits (234), Expect = 7e-19
Identities = 81/326 (24%), Positives = 147/326 (44%), Gaps = 39/326 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
M + + + G G +GS I L++ DV ++ E ++ D ++
Sbjct: 1 MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRD-------------ELNLLDSRAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS--VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ +S D V+ AA++ V + F + N++ NI+ A + + KL+F
Sbjct: 48 HDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ-NMMIESNIIHAAHQNDVNKLLFLG 106
Query: 116 SAAVYGEPTSLPIREDH----PLNPIS-PYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + P+ E L P + P ++K++G C+ + + YG + N+
Sbjct: 107 SSCIYPKLAKQPMAESELLQGTLEPTNEPEAIAKIAGIKLCESYNRQYGRDYRSVMPTNL 166
Query: 171 YGPRQ------SSAYAGVISIFMERALRGEP-LVIFGDGKQSRDFVYVKDVVEANILVAE 223
YGP S ++ F E + P +V++G G R+F++V D+ A+I V E
Sbjct: 167 YGPHDNFHPSNSHVIPALLRRFHEATAQSAPDVVVWGSGTPMREFLHVDDMAAASIHVME 226
Query: 224 --------KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVAD 275
+ NVGTG + TI ELA I ++ +++F +P R + D
Sbjct: 227 LAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLD 286
Query: 276 IEKIKKLGFKPRYSLEEGLLETWKWF 301
+ ++ +LG+ SLE GL T++WF
Sbjct: 287 VTRLHQLGWYHEISLEAGLASTYQWF 312
>dbj|BAA05020.1| (D25537) HrEpiB [Halocynthia roretzi]
Length = 241
Score = 93.6 bits (229), Expect = 3e-18
Identities = 66/214 (30%), Positives = 110/214 (50%), Gaps = 14/214 (6%)
Query: 4 KLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEG----VKFIEADVRDYE 58
K ++VTGGAG++GS + L +E +V V D G +P +K ++ DV D E
Sbjct: 23 KKVLVTGGAGYLGSTMVPMLLDEGFEVTVYDCFSWGISPLLPLASNPRLKIVKGDVLDEE 82
Query: 59 SIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSAA 118
S+ E++ AD + H AA + KDP + VNV GT NI + L +G +L++AS+ +
Sbjct: 83 SLKEVMKDADAIVHLAAIVGYPACSKDPELAKNVNVTGTKNITKNLKQGQ-RLVYASTGS 141
Query: 119 VYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSA 178
YG T + ED P++P++ YG +K GE + V V LR V+G
Sbjct: 142 CYGAVTGM-CTEDTPISPLTLYGSTKADGEKLVR------DVGGVGLRLATVFGISPRLR 194
Query: 179 YAGVISIFMERALRGEPLVIFGDGKQSRDFVYVK 212
+++ +A++ ++ +G R F++V+
Sbjct: 195 LDLLVNDLTNKAIKMRTFDLY-EGSFRRTFLHVR 227
>pir||S74432 hypothetical protein sll1213 - Synechocystis sp. (strain PCC 6803)
>gi|1651656|dbj|BAA16584.1| (D90899) hypothetical
protein [Synechocystis sp.]
Length = 312
Score = 93.2 bits (228), Expect = 3e-18
Identities = 82/320 (25%), Positives = 142/320 (43%), Gaps = 29/320 (9%)
Query: 1 MRNKLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYES 59
+ N+ I+VTGGAGF+G +A+ + D I +P + D+R +
Sbjct: 4 LENQRILVTGGAGFLGKQVVAQLIAAGGDRPKI---------TIPRSK---DCDLRQASA 51
Query: 60 IAEIVSSADYVFHEAAQI-SVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSA 117
V + D V H AA + + + + P N++ + ++ A + G K + +
Sbjct: 52 CERAVENQDIVIHLAAHVGGIGLNREKPAELFYDNLMMGVQLIHAAHQAGVKKFVCVGTI 111
Query: 118 AVYGEPTSLPIRED-----HPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG 172
Y + T +P +E+ +P +PYGV+K + + + YG + L N+YG
Sbjct: 112 CAYPKFTPVPFKEEDLWNGYPEETNAPYGVAKKALLVQLESYRLQYGFNGIYLLPVNLYG 171
Query: 173 ------PRQSSAYAGVISIFMERALRGE-PLVIFGDGKQSRDFVYVKDVVEANILVAEKR 225
PR S +I E G+ L ++GDG +R+F+Y D I++ +
Sbjct: 172 PEDNFDPRSSHVIPALIHKVYEAQKAGQKQLPVWGDGSPTREFLYSTDAAR-GIVMGTQA 230
Query: 226 RAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGF 284
+ + N+GT E +I +L I EL I++ +P R D K K + GF
Sbjct: 231 YDKADPVNLGTNFEISIKDLTELICELMEFEGDIIWETDQPNGQPRRCLDTTKAKAEFGF 290
Query: 285 KPRYSLEEGLLETWKWFKSR 304
+ + SL EGL T W++ +
Sbjct: 291 EAQVSLREGLKNTIDWYRQQ 310
>gi|9631863 similar to Mycobacterium ORF, corresponds to GenBank Accession
Number Z79701 [Paramecium bursaria Chlorella virus 1]
>gi|7461438|pir||T17792 hypothetical protein A295L -
Chlorella virus PBCV-1 >gi|1181458|gb|AAC96663.1|
(U42580) similar to Mycobacterium ORF, corresponds to
GenBank Accession Number Z79701 [Paramecium bursaria
Chlorella virus 1]
Length = 317
Score = 86.6 bits (211), Expect = 3e-16
Identities = 73/311 (23%), Positives = 139/311 (44%), Gaps = 34/311 (10%)
Query: 2 RNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIA 61
++ I V G G +GS + L++E +I S K E D+ + + +
Sbjct: 5 KHSKIYVAGHTGMVGSSLVRLLQKEGYTNIITR--SSK-----------ELDLTNQQEVT 51
Query: 62 EI--VSSADYVFHEAAQIS---VEESVKDPVFTEEVNVIGTINILRALSEGN-GKLIFAS 115
+ + +YVF AA++ S + N++ N++ A N KL+F
Sbjct: 52 AFFEMETPEYVFLAAAKVGGIHANNSFGGDFIRD--NLMIQTNVIHASKTFNVKKLVFLG 109
Query: 116 SAAVYGEPTSLPIREDHPLNPI-----SPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNV 170
S+ +Y + + PI+E++ + PY + +++G C + + +G V + N+
Sbjct: 110 SSCIYPKESPNPIKEEYLMTGFLEPTNKPYAIERIAGIEMCDAYRKQFGCNFVSVMPTNL 169
Query: 171 YGP------RQSSAYAGVISIFMERALRGEPLV-IFGDGKQSRDFVYVKDVVEANILVAE 223
GP + + +I F E + P V ++G G R+F++V D+ ++V E
Sbjct: 170 SGPNDRYDLQNGHVFPVLIRKFYEAMINKVPSVKLWGTGIARREFLHVDDLARGLLIVME 229
Query: 224 KRRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLG 283
K G N+G G + +I ELA + ++ I++ P + + D KIK LG
Sbjct: 230 KYNEPGP-INIGYGSDVSISELAELVRDIVGYKGAIIYDTYMPDGTLKKLIDSTKIKSLG 288
Query: 284 FKPRYSLEEGL 294
++P+ SL + +
Sbjct: 289 WEPKISLIDNI 299
>pir||D70393 GDP-D-mannose dehydratase - Aquifex aeolicus
>gi|2983560|gb|AAC07133.1| (AE000722) GDP-D-mannose
dehydratase [Aquifex aeolicus]
Length = 345
Score = 85.8 bits (209), Expect = 6e-16
Identities = 83/327 (25%), Positives = 147/327 (44%), Gaps = 37/327 (11%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSG-------KPENVPEGVKFIEAD 53
M K ++TG G G+++A+ L E+ V + SG K + VK I D
Sbjct: 1 MSGKRALITGIRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHMD 60
Query: 54 VRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS--EGNG 109
+ ++ +I + D V++ AAQ V S + P+ T EV+ IG + IL AL + +
Sbjct: 61 LLEFSNIIRTIEKVQPDEVYNLAAQSFVGVSFEQPILTAEVDAIGVLRILEALRTVKPDT 120
Query: 110 KLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
K AS++ ++G+ +P E P P SPY V+K+ G + + Y + FN
Sbjct: 121 KFYQASTSEMFGKVQEIPQTEKTPFYPRSPYAVAKLFGHWITVNYREAYNMFACSGILFN 180
Query: 170 VYGPRQSSAY-AGVISIFMERALRG-EPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRA 227
P + + I+ + R G + ++ G+ RD+ Y + VEA L+ + +
Sbjct: 181 HESPLRGIEFVTRKITYSLARIKYGLQDKLVLGNLNAKRDWGYAPEYVEAMWLMMQ--QP 238
Query: 228 EGETFNVGTGRETTIIELAMKIIELSS-----------------TSSQILFSKP----RP 266
E + + + TG T+ E K +++ + +++ RP
Sbjct: 239 EPDDYVIATGETHTVREFVEKAAKIAGFDIEWVGEGINEKGIDRNTGKVIVEVSEEFFRP 298
Query: 267 GDIRRSVADIEK-IKKLGFKPRYSLEE 292
++ V + EK +KKLG+KPR + +E
Sbjct: 299 AEVDILVGNPEKAMKKLGWKPRTTFDE 325
>pir||C81288 probable sugar-nucleotide epimerase/dehydratease Cj1427c [imported]
- Campylobacter jejuni (strain NCTC 11168)
>gi|6968856|emb|CAB73851.1| (AL139078) putative
sugar-nucleotide epimerase/dehydratease [Campylobacter
jejuni]
Length = 313
Score = 85.8 bits (209), Expect = 6e-16
Identities = 83/312 (26%), Positives = 146/312 (46%), Gaps = 23/312 (7%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVP----EGVKFIEADVRDY 57
+K +++TGGAG+IGS + L E+ +V VIDNL + + + FI D D
Sbjct: 2 SKKVLITGGAGYIGSVLTPILLEKGYEVCVIDNLMFDQISLLSCFHNKNFTFINGDAMDE 61
Query: 58 ESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASSA 117
I + V+ AD + AA + ++P + +N + ++ + + I+ ++
Sbjct: 62 NLIRQEVAKADIIIPLAALVGAPLCKRNPKLAKMINY-EAVKMISDFASPSQIFIYPNTN 120
Query: 118 AVYG--EPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQ 175
+ YG E ++ E+ PL PIS YG+ KV E Y L V R V+G
Sbjct: 121 SGYGIGEKDAM-CTEESPLRPISEYGIDKVHAEQYL-----LDKGNCVTFRLATVFGISP 174
Query: 176 SSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEK-RRAEGETFNV 234
+++ F RA R + +V+F + + R++++V+DVV+ I E + +G+ +N+
Sbjct: 175 RMRLDLLVNDFTYRAYRDKFIVLFEEHFR-RNYIHVRDVVKGFIHGIENYDKMKGQAYNM 233
Query: 235 GTG----RETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGFKPRYSL 290
G + + E K I S + P D R + K++ G+KP +L
Sbjct: 234 GLSSANLTKRQLAETIKKYIPDFYIHSANIGEDP---DKRDYLVSNTKLEATGWKPDNTL 290
Query: 291 EEGLLETWKWFK 302
E+G+ E + FK
Sbjct: 291 EDGIKELLRAFK 302
>gb|AAF23991.1| (AF035937) WbpV [Pseudomonas aeruginosa]
Length = 320
Score = 85.4 bits (208), Expect = 7e-16
Identities = 90/326 (27%), Positives = 142/326 (42%), Gaps = 39/326 (11%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVVVIDNLYSG---KPENVPEGVKFIEADVRDYESIAE 62
++VTG GFIG+ + +L V ++G + P GV + + +
Sbjct: 6 VLVTGATGFIGAALVNSLCSSGQYKV----WAGCRRRGGAWPRGVTPLLLGELGSSVVWD 61
Query: 63 IVSSADYVFHEAAQISV-EESVKDPVFT-EEVNVIGTINILR-ALSEGNGKLIFASSAAV 119
S+ D V H AA++ V E+ DP+ + NV GT+++ R A+S G + IF SS V
Sbjct: 62 AESAIDTVVHCAARVHVMSETASDPLVEFRKANVQGTLDLAREAVSRGVRRFIFISSIKV 121
Query: 120 YGEPTS--LPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS 177
GE T P D P NP+ PYGVSK E + G+ VI+R VYGP
Sbjct: 122 NGEGTEPGRPYTADSPPNPVDPYGVSKREAEQALLDLAEETGLEVVIIRPVLVYGP---- 177
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTG 237
+ M RG PL + G R V + ++V+ I E A G+ F V G
Sbjct: 178 GVKANVQTMMRWLKRGVPLPL-GAIHNRRSLVSLDNLVDLIITCIEHPAAVGQVFLVSDG 236
Query: 238 RETTIIELAMKIIELSSTSSQIL------------------FSKPRPGDIRRSVADIEKI 279
+ + EL ++ +++L F++ G ++ DI K
Sbjct: 237 EDLSTTELLRRMGRALGAPARLLPVPASWIGAAAKVLNRQAFARRLCGSLQ---VDIMKT 293
Query: 280 KK-LGFKPRYSLEEGLLETWKWFKSR 304
++ LG+ P +++ L +T + F R
Sbjct: 294 RQVLGWTPPVGVDQALEKTARSFLDR 319
>gi|9631687 similar to Yersinia GDP-D-mannose dehydratase, corresponds to
GenBank Accession Number U46859 [Paramecium bursaria
Chlorella virus 1] >gi|7448654|pir||T17608 probable
GDPmannose 4,6-dehydratase (EC 4.2.1.47) - Chlorella
virus PBCV-1 >gi|1131462|gb|AAC96486.1| (U42580) similar
to Yersinia GDP-D-mannose dehydratase, corresponds to
GenBank Accession Number U46859 [Paramecium bursaria
Chlorella virus 1]
Length = 345
Score = 84.3 bits (205), Expect = 2e-15
Identities = 80/333 (24%), Positives = 153/333 (45%), Gaps = 43/333 (12%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVV--VIDNLYSGKP---ENVPEGVKFIEADVR 55
M +K+ +VTG G G+++ L ++ V ++ + S P E +GV+ + D+
Sbjct: 1 MLSKVALVTGATGQDGTYLCPFLVKKGYTVYGLVRHTSSENPRVEELKSQGVEIVHGDLT 60
Query: 56 DYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEG--NGKL 111
D S+ I++ D +++ AAQ V +S T V+ +G + +L A+ N ++
Sbjct: 61 DSASLINIITKIRPDEIYNMAAQSFVGDSFHQAEVTANVDALGVLRLLDAVRIAGLNSRI 120
Query: 112 IFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
AS++ +YG+ +P E P P SPYGV+K+ CK + + YG+ FN
Sbjct: 121 CQASTSELYGKVQEIPQTERTPFYPRSPYGVAKLYAYWICKNYRESYGMFVCNSICFNHE 180
Query: 172 GPRQSSAY-AGVISIFMERALRG-EPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEG 229
P + + I+ + G E + G+ RD+ Y +D +EA L+ ++
Sbjct: 181 SPNRGHQFVTRKITKAVANIFNGVEKCMYLGNIDSKRDWGYAEDYIEAMWLMLQQDTP-- 238
Query: 230 ETFNVGTGRETTI---IELAMKIIEL-----SSTSSQILF--SKP--------------- 264
+ + + TG+ T++ +++A ++++ ++I + S P
Sbjct: 239 DDYVIATGQTTSVREFVKIAFGVLDIVVEFSGENENEIAYVVSSPEASHVKVGDVVMRVN 298
Query: 265 ----RPGDIRRSVADIEKIKK-LGFKPRYSLEE 292
RP ++ V D K K LG++P+ +L E
Sbjct: 299 KDFYRPAEVDLLVGDATKAKSVLGWEPKTTLNE 331
>pir||T05987 hypothetical protein F17M5.120 - Arabidopsis thaliana
>gi|4490303|emb|CAB38794.1| (AL035678) putative protein
[Arabidopsis thaliana] >gi|7270284|emb|CAB80053.1|
(AL161583) putative protein [Arabidopsis thaliana]
Length = 344
Score = 80.4 bits (195), Expect = 2e-14
Identities = 92/332 (27%), Positives = 136/332 (40%), Gaps = 36/332 (10%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAE 62
N I+VTG G++G+ + L V + ++P V+ DV DY S+ +
Sbjct: 12 NMKILVTGSTGYLGARLCHVLLRRGHSVRALVRRTSDLSDLPPEVELAYGDVTDYRSLTD 71
Query: 63 IVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN--GKLIFASSAAVY 120
S D VFH AA VE + DP VNV G N+L A+ E K+I+ SS
Sbjct: 72 ACSGCDIVFHAAA--LVEPWLPDPSRFISVNVGGLKNVLEAVKETKTVQKIIYTSSFFAL 129
Query: 121 GEPTSLPIREDHPLNP---ISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSS 177
G E+ N + Y SK + + GVP ++L ++GP + +
Sbjct: 130 GSTDGSVANENQVHNERFFCTEYERSKAVADKMA-LNAASEGVPIILLYPGVIFGPGKLT 188
Query: 178 AYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRR--------AEG 229
+ V + +ER G G G F +V DVVE ++ EK R E
Sbjct: 189 SANMVARMLIER-FNGRLPGYIGSGTDRYSFSHVDDVVEGHVAAMEKGRLGERYLLTGEN 247
Query: 230 ETFNV---------GTGRETTIIEL-------AMKIIELSSTSSQILFSKPRPGDIRRSV 273
+F + GT + I L + ++ T L S P +R
Sbjct: 248 ASFKLVFDMAALITGTKKPNFSIPLWAINAYGWLSVLISRVTGKLPLISPPTVTVLRHQW 307
Query: 274 A-DIEKIK-KLGFKPRYSLEEGLLETWKWFKS 303
+ +K K +LG+ PR SL+EGL E W KS
Sbjct: 308 SYSCDKAKLELGYNPR-SLKEGLEEMLPWLKS 338
>gb|AAB24744.1| (S51942) orf6=nolK [Azorhizobium caulinodans, ORS571, Peptide, 328
aa]
Length = 328
Score = 79.6 bits (193), Expect = 4e-14
Identities = 72/317 (22%), Positives = 139/317 (43%), Gaps = 32/317 (10%)
Query: 2 RNKLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
+ K +++TGG G +G + IA A + +++ + ++ D+R+ E++
Sbjct: 19 KGKKLLITGGRGMVGRNLIACAARSGWEIIAPTS---------------VDLDLRNAEAV 63
Query: 61 AEIVSSA--DYVFHEAAQIS-VEESVKDPVFTEEVNVIGTINILRALSEGNG-KLIFASS 116
+ + D V H A + + ++ DP+ N +N++ + LI SS
Sbjct: 64 EQYIRRQLPDVVVHAAGVVGGIHANIADPIHFLADNAAMALNVVMSSFRSEVVTLINLSS 123
Query: 117 AAVYGEPTSLPIRE-DHPLNPISP----YGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ +Y P++E D P Y ++K G C+ +L L N+Y
Sbjct: 124 SCMYPACIEGPLKECDILRGPFEVTNEGYALAKTVGLKICEYIDKLPNFNYKTLIACNLY 183
Query: 172 G------PRQSSAYAGVISIFMERALRG-EPLVIFGDGKQSRDFVYVKDVVEANILVAEK 224
G PR+S +I + + G E + I+GDG R+F++ D + I E
Sbjct: 184 GVGDNFDPRRSHLLPAIIEKIHKASQCGSESVSIWGDGTARREFMFAYDFAKIIIKALEV 243
Query: 225 RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGF 284
+ NVG G++ +++E + + S + ++ RP +R + DI + LG+
Sbjct: 244 PELIPSSMNVGVGKDLSVLEYYSLVARVIGWSGEFVYDLNRPVGMRSKLMDITHLTALGW 303
Query: 285 KPRYSLEEGLLETWKWF 301
P SLE G+ T++++
Sbjct: 304 VPERSLEGGIRSTYQYY 320
>pir||S74751 CDP-glucose 4,6-dehydratase - Synechocystis sp. (strain PCC 6803)
>gi|1651976|dbj|BAA16902.1| (D90901) CDP-glucose
4,6-dehydratase [Synechocystis sp.]
Length = 360
Score = 79.6 bits (193), Expect = 4e-14
Identities = 90/332 (27%), Positives = 140/332 (42%), Gaps = 31/332 (9%)
Query: 2 RNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIE---------- 51
+ K + +TG GF GS + L + V + YS P P + E
Sbjct: 8 QGKSVFLTGHTGFKGSWLTLWLSQLGAKV---SGYSLDPLTNPNLCELAEIAKCLRSDTR 64
Query: 52 ADVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRAL--SEG 107
ADV D ++ + ++ A + VFH AAQ V S +DPV T NV+GT ++L AL S+
Sbjct: 65 ADVNDLANLQKAIAEARPEIVFHLAAQPLVRRSYRDPVGTFATNVMGTAHLLEALRASDS 124
Query: 108 NGKLIFASSAAVY-GEPTSLPIREDHPLNPISPYGVSKVSGE----HYCKVFYQLYGVPT 162
++ ++ VY P RED L PY SK + E Y F + GV
Sbjct: 125 VRVVVIVTTDKVYRNVEWCWPYREDDQLGGHDPYSASKAACEIVVASYRDAFLREQGVAV 184
Query: 163 VILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVA 222
R NV G S + + RAL + +VI + R + +V + + +L+A
Sbjct: 185 ASARAGNVIGGGDWSEDRLIPDVV--RALDAKTMVIIRRPQAIRPWQHVLEPLAGYLLLA 242
Query: 223 EKRRAEGETFNV-GTGRETTIIELAMKIIELSS---TSSQILFSKPRPGDIRRSVADIEK 278
+K E G ET +I+E +S Q+ + G +E
Sbjct: 243 QKLWHSPELAGAYNLGPETKDAATVRQILEFASRIEPGLQVEYGDGNEGPHEAGWLSLEI 302
Query: 279 IKK---LGFKPRYSLEEGLLETWKWFKSRTLG 307
K LG++P + +EE + T W++S+ G
Sbjct: 303 AKARTLLGYRPSWGVEEAVRRTMIWYRSQRQG 334
>sp|P33217|NOLK_AZOCA NODULATION PROTEIN NOLK
Length = 312
Score = 79.6 bits (193), Expect = 4e-14
Identities = 72/317 (22%), Positives = 139/317 (43%), Gaps = 32/317 (10%)
Query: 2 RNKLIVVTGGAGFIGSH-IAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESI 60
+ K +++TGG G +G + IA A + +++ + ++ D+R+ E++
Sbjct: 3 KGKKLLITGGRGMVGRNLIACAARSGWEIIAPTS---------------VDLDLRNAEAV 47
Query: 61 AEIVSSA--DYVFHEAAQIS-VEESVKDPVFTEEVNVIGTINILRALSEGNG-KLIFASS 116
+ + D V H A + + ++ DP+ N +N++ + LI SS
Sbjct: 48 EQYIRRQLPDVVVHAAGVVGGIHANIADPIHFLADNAAMALNVVMSSFRSEVVTLINLSS 107
Query: 117 AAVYGEPTSLPIRE-DHPLNPISP----YGVSKVSGEHYCKVFYQLYGVPTVILRYFNVY 171
+ +Y P++E D P Y ++K G C+ +L L N+Y
Sbjct: 108 SCMYPACIEGPLKECDILRGPFEVTNEGYALAKTVGLKICEYIDKLPNFNYKTLIACNLY 167
Query: 172 G------PRQSSAYAGVISIFMERALRG-EPLVIFGDGKQSRDFVYVKDVVEANILVAEK 224
G PR+S +I + + G E + I+GDG R+F++ D + I E
Sbjct: 168 GVGDNFDPRRSHLLPAIIEKIHKASQCGSESVSIWGDGTARREFMFAYDFAKIIIKALEV 227
Query: 225 RRAEGETFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIKKLGF 284
+ NVG G++ +++E + + S + ++ RP +R + DI + LG+
Sbjct: 228 PELIPSSMNVGVGKDLSVLEYYSLVARVIGWSGEFVYDLNRPVGMRSKLMDITHLTALGW 287
Query: 285 KPRYSLEEGLLETWKWF 301
P SLE G+ T++++
Sbjct: 288 VPERSLEGGIRSTYQYY 304
>gb|AAB49434.1| (U73374) Cap8E [Staphylococcus aureus]
Length = 342
Score = 79.2 bits (192), Expect = 6e-14
Identities = 78/278 (28%), Positives = 125/278 (44%), Gaps = 36/278 (12%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEG-----VKFIEADVRD 56
+K++++TGG G G+ + + + N + I + K +++ + +KF DVRD
Sbjct: 4 DKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFYIGDVRD 63
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASS 116
+S+ + DYVFH AA V PV + N+IGT N+L++ N K + S
Sbjct: 64 SQSVETAMRDVDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIHQNVKKVICLS 123
Query: 117 AAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFY----QLYGVPTVI--LRYFNV 170
D PI+ G+SK E KVF + T+I RY NV
Sbjct: 124 T-------------DKAAYPINAMGISKAMME---KVFVAKSRNIRSEQTLICGTRYGNV 167
Query: 171 YGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
R S VI +F+++ GEPL I D +R + ++D VE ++V + AE
Sbjct: 168 MASRGS-----VIPLFIDKIKAGEPLTI-TDPDMTRFLMSLEDAVE--LVVHAFKHAETG 219
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGD 268
V +T+ +LA ++EL + I R G+
Sbjct: 220 DIMVQKAPSSTVGDLATALLELFEADNAIEIIGTRHGE 257
>gb|AAC46088.1| (U81973) Cap5E [Staphylococcus aureus]
Length = 342
Score = 79.2 bits (192), Expect = 6e-14
Identities = 78/278 (28%), Positives = 125/278 (44%), Gaps = 36/278 (12%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVPEG-----VKFIEADVRD 56
+K++++TGG G G+ + + + N + I + K +++ + +KF DVRD
Sbjct: 4 DKILLITGGTGSFGNAVMKQFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFYIGDVRD 63
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASS 116
+S+ + DYVFH AA V PV + N+IGT N+L++ N K + S
Sbjct: 64 SQSVETAMRDVDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIHQNVKKVICLS 123
Query: 117 AAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFY----QLYGVPTVI--LRYFNV 170
D PI+ G+SK E KVF + T+I RY NV
Sbjct: 124 T-------------DKAAYPINAMGISKAMME---KVFVAKSRNIRSEQTLICGTRYGNV 167
Query: 171 YGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGE 230
R S VI +F+++ GEPL I D +R + ++D VE ++V + AE
Sbjct: 168 MASRGS-----VIPLFIDKIKAGEPLTI-TDPDMTRFLMSLEDAVE--LVVHAFKHAETG 219
Query: 231 TFNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGD 268
V +T+ +LA ++EL + I R G+
Sbjct: 220 DIMVQKAPSSTVGDLATALLELFEADNAIEIIGTRHGE 257
>dbj|BAB03206.1| (AB046360) unknown [Actinobacillus actinomycetemcomitans]
Length = 294
Score = 77.6 bits (188), Expect = 2e-13
Identities = 81/310 (26%), Positives = 147/310 (47%), Gaps = 31/310 (10%)
Query: 6 IVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIEADVRDYESIAEIV- 64
I+VTGG+GFIG ++ L+E+ + V V E + D+ + S+ ++
Sbjct: 3 ILVTGGSGFIGKNLIYLLREKREFEVFG-------ATVEETM-----DLTNPCSVQSVLE 50
Query: 65 -SSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGN----GKLIFASSAAV 119
+ D++ H AA V + +P+ VN IGT N+LR++ + N G L F S+A +
Sbjct: 51 KTKPDFIVHLAALTFVPNN--NPITFYLVNTIGTENLLRSIVDLNVAKLGVLCF-STAGI 107
Query: 120 YGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYGPRQSSAY 179
YG + + E P++ Y +SK EH + G+ ++R FNV G Q+ +
Sbjct: 108 YGIQETKLLSESLTPKPVNHYSMSKHCMEHIVNKYRCFRGI--TVVRPFNVLGLGQNINF 165
Query: 180 AGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFNVGTGRE 239
++ + ++ + + G+ RDF+ V D + + K E ET N+ TG
Sbjct: 166 --LVPKMVSAFVKKDKTIELGNLDSVRDFISVNDCCDIIYRLISK-LIENETINICTGIG 222
Query: 240 TTIIELAMKIIELSSTSSQILFSK--PRPGDIRRSVADIEK-IKKLGFKPRYSLEEGLLE 296
++ ++ + E+S +I ++ R DI + + D K + LG R++ +LE
Sbjct: 223 YSVYQIFQLLCEISMHQMEIKQNELFVRHDDIPQMIGDPSKLLNVLGNDYRFTSVRAILE 282
Query: 297 TWKWFKSRTL 306
+ +K+R L
Sbjct: 283 --EMYKNRLL 290
>pir||S44233 strP protein - Streptomyces glaucescens >gi|581674|emb|CAA55575.1|
(X78974) strP [Streptomyces glaucescens]
>gi|3256048|emb|CAA07376.1| (AJ006985) StrP
[Streptomyces glaucescens]
Length = 358
Score = 76.1 bits (184), Expect = 5e-13
Identities = 81/313 (25%), Positives = 139/313 (43%), Gaps = 18/313 (5%)
Query: 6 IVVTGGAGFIGSHIAEALKEE-NDVVVIDN-LYSGK---PENVPEGVKFIEADVRDYESI 60
I++TG G++G+ +A L + V +D+ L++ + +VP+ V + D+RD
Sbjct: 3 ILLTGHQGYLGTVMAPVLTAAGHQVTGLDSGLFASRVLGALDVPD-VPGLALDLRDVT-- 59
Query: 61 AEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNGKLIFASSAAV 119
+ + D V H AA + DP T VN + + R E G + +AS+ +V
Sbjct: 60 VDTLRGYDAVVHLAALSNDPLGSLDPELTHAVNHHASTRLARLAKEAGVTRFAYASTCSV 119
Query: 120 YGEPTS-LPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFNVYG--PRQS 176
YG + P+ ED PL P++PY VSKV E V G LR +G PR
Sbjct: 120 YGAQSGDAPVDEDAPLKPVTPYAVSKVRVEDDL-VELADSGFAPFFLRNATAFGFSPRLR 178
Query: 177 SAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANI--LVAEKRRAEGETFNV 234
S V++ + RA+ G + + DG R V+ +D+ A + L A FN+
Sbjct: 179 SDI--VLNNLVGRAVLGGRVTVLSDGTAWRPLVHAEDIARAVLAGLAAPAATVRARAFNI 236
Query: 235 GTGRETTIIELAMKIIELSSTSSQILFSKPRPGDIRRSVADIEKIK-KLGFKPRYSLEEG 293
GT + + + S + S D R D + + +LG + +++ +G
Sbjct: 237 GTEENNRTVAEIAEAAAAAVPGSVVEISGETGNDPRSYRVDFTRARTELGHRATWTIPDG 296
Query: 294 LLETWKWFKSRTL 306
+ + +++R L
Sbjct: 297 AAQLAREYRARGL 309
>sp|P26397|RFBG_SALTY CDP-GLUCOSE 4,6-DEHYDRATASE >gi|96842|pir||S15305 rfbG protein -
Salmonella typhimurium >gi|47895|emb|CAA40121.1|
(X56793) CDP-glucose 4,6-dehydratase [Salmonella
enterica]
Length = 359
Score = 75.7 bits (183), Expect = 6e-13
Identities = 84/333 (25%), Positives = 136/333 (40%), Gaps = 36/333 (10%)
Query: 2 RNKLIVVTGGAGFIGSHIAEALKEENDVVVIDNLYSGKPENVPEGVKFIE---------A 52
+ K + VTG GF GS ++ L E +V Y+ VP + +
Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIV---KGYALDAPTVPSLFEIVRLNDLMESHIG 64
Query: 53 DVRDYESIAEIVSS--ADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSE-GNG 109
D+RD+E + ++ + VFH AAQ V S + P+ T NV+GT+++L + + GN
Sbjct: 65 DIRDFEKLRNSIAEFKPEIVFHMAAQPLVRLSYEQPIETYSTNVMGTVHLLETVKQVGNI 124
Query: 110 KLI--FASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVF---------YQLY 158
K + S RE+ P+ PY SK E F Y+ +
Sbjct: 125 KAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKGCAELVASAFRNSFFNPANYEQH 184
Query: 159 GVPTVILRYFNVYGPRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEAN 218
GV +R NV G + + I R+ VI + R + +V + +
Sbjct: 185 GVGLASVRAGNVIGGGDWAKDRLIPDIL--RSFENNQQVIIRNPYSIRPWQHVLEPLSGY 242
Query: 219 ILVAEKRRAEGETFNVGTG------RETTIIELAMKIIEL-SSTSSQILFSKPRPGDIRR 271
I+VA++ EG F+ G T+ + K++ L +S +L + P +
Sbjct: 243 IVVAQRLYTEGAKFSEGWNFGPRDEDAKTVEFIVDKMVTLWGDDASWLLDGENHPHEAHY 302
Query: 272 SVADIEKIK-KLGFKPRYSLEEGLLETWKWFKS 303
D K +LG+ PR+ L E L KW K+
Sbjct: 303 LKLDCSKANMQLGWHPRWGLTETLGRIVKWHKA 335
>gb|AAD12955.1| (AF078135) unknown [Leptospira borgpetersenii]
Length = 336
Score = 75.7 bits (183), Expect = 6e-13
Identities = 80/296 (27%), Positives = 128/296 (43%), Gaps = 31/296 (10%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVP-----EGVKFIEADVRD 56
NK++++TGG G G + + N + I + K E++ E VKF DVRD
Sbjct: 4 NKILMITGGTGSFGDTVLKRFLGTNVKEIRIFSRDEKKQEDMRISLSNEKVKFYIGDVRD 63
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASS 116
Y+SI + DY+FH AA V P+ + NV+GT N+L A K + S
Sbjct: 64 YDSIFQSTIGVDYIFHAAALKQVPSCEFYPMEAIKTNVVGTENVLNAAIANRVKKVVLLS 123
Query: 117 AAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVIL---RYFNVYGP 173
D + PI+ G+SK E + IL RY NV
Sbjct: 124 T-------------DKAVYPINAMGISKAMAEKLLVAKSRTILEGRTILCATRYGNVMAS 170
Query: 174 RQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETFN 233
R S VI +F+E+ + PL + D +R + ++D V+ +L A +G+ F
Sbjct: 171 RGS-----VIPLFIEQIKKNIPLTV-TDPNMTRFLMSLEDSVDL-VLHAFNHGQQGDIF- 222
Query: 234 VGTGRETTIIELAMKIIELSSTSSQILFSKPRPGD-IRRSVADIEKIKKLGFKPRY 288
+ +T+ +LA +I + ++I R G+ + S+ E++ K RY
Sbjct: 223 IQKSPASTVQDLAEALIAIFKKENKISIIGTRHGEKLYESLVSREEMAKAEDMGRY 278
>sp|P77398|YFBG_ECOLI HYPOTHETICAL 74.3 KD PROTEIN IN AIS-PMRD INTERGENIC REGION
>gi|7466308|pir||E64996 hypothetical protein b2255 -
Escherichia coli (strain K-12)
>gi|1788589|gb|AAC75315.1| (AE000315) putative
transformylase [Escherichia coli K12]
>gi|1799607|dbj|BAA16078.1| (D90856) METHIONYL-TRNA
FORMYLTRANSFERASE (EC 2.1.2.9). [Escherichia coli]
>gi|1799612|dbj|BAA16082.1| (D90857) METHIONYL-TRNA
FORMYLTRANSFERASE (EC 2.1.2.9). [Escherichia coli]
Length = 660
Score = 74.5 bits (180), Expect = 1e-12
Identities = 70/263 (26%), Positives = 113/263 (42%), Gaps = 21/263 (7%)
Query: 2 RNKLIVVTGGAGFIGSHIAEALKEENDVVV----IDNLYSGKPENVPEGVKFIEADVRDY 57
R +++ G GFIG+H+ E L E+ V I + + N P F+E D+ +
Sbjct: 314 RRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPH-FHFVEGDISIH 372
Query: 58 ESIAEI-VSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALSEGNGKLIFASS 116
E V D V A + E ++P+ E++ + I+R + ++IF S+
Sbjct: 373 SEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPST 432
Query: 117 AAVYGEPTSLPIREDH------PLN-PISPYGVSKVSGEHYCKVFYQLYGVPTVILRYFN 169
+ VYG + EDH P+N P Y VSK + + + G+ + R FN
Sbjct: 433 SEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFN 492
Query: 170 VYGPRQSSAYAG------VISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAE 223
GPR + A I+ + + G P+ + GKQ R F ++D +EA + E
Sbjct: 493 WMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIE 552
Query: 224 K--RRAEGETFNVGTGRETTIIE 244
R +GE N+G IE
Sbjct: 553 NAGNRCDGEIINIGNPENEASIE 575
>gb|AAD52172.1|AF144879_11 (AF144879) unknown [Leptospira interrogans]
Length = 336
Score = 74.5 bits (180), Expect = 1e-12
Identities = 79/290 (27%), Positives = 131/290 (44%), Gaps = 33/290 (11%)
Query: 3 NKLIVVTGGAGFIGSHIAEALKEEN-DVVVIDNLYSGKPENVP-----EGVKFIEADVRD 56
NK++++TGG G G+ + + N + I + K E++ E VKF DVRD
Sbjct: 4 NKILMITGGTGSFGNTVLKRFLGTNVKEIRIFSRDEKKQEDMRISLSNEKVKFYIGDVRD 63
Query: 57 YESIAEIVSSADYVFHEAAQISVEESVKDPVFTEEVNVIGTINILR-ALSEGNGKLIFAS 115
Y+SI + DY+FH AA V P+ + NV+GT NIL A++ K++ S
Sbjct: 64 YDSIFQSTIGVDYIFHAAALKQVPSCEFYPMEAIKTNVVGTENILNAAIANRVQKVVLLS 123
Query: 116 SAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVPTVIL---RYFNVYG 172
+ D + PI+ G+SK E + IL RY NV
Sbjct: 124 T--------------DKAVYPINAMGISKAMAEKLLVAKSRTIPEGRTILCATRYGNVMA 169
Query: 173 PRQSSAYAGVISIFMERALRGEPLVIFGDGKQSRDFVYVKDVVEANILVAEKRRAEGETF 232
R S VI +F+E+ + PL + D +R + ++D V+ +L A +G+ F
Sbjct: 170 SRGS-----VIPLFIEQIKKNIPLTV-TDPNMTRFLMSLEDSVDL-VLHAFNHGQQGDIF 222
Query: 233 NVGTGRETTIIELAMKIIELSSTSSQILFSKPRPGD-IRRSVADIEKIKK 281
+ +T+ +LA +I + ++I R G+ + S+ E++ K
Sbjct: 223 -IQKSPASTVQDLAEALIGIFKKENKISIIGTRHGEKLYESLVSREEMAK 271
>gb|AAF45032.1|AF146601_1 (AF146601) putative GDP-D-mannose dehydratase [Aeromonas
hydrophila]
Length = 377
Score = 74.1 bits (179), Expect = 2e-12
Identities = 83/350 (23%), Positives = 152/350 (42%), Gaps = 66/350 (18%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVV-------------IDNLYSGKPENVPEGV 47
M K+ ++TG G GS++AE L E+ V ID++Y P +
Sbjct: 4 MNKKVALITGVTGQDGSYLAEFLLEKGYQVHGIKRRASSFNTQRIDHIYQD-PHIEHQNF 62
Query: 48 KFIEADVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS 105
D+ D ++ I+ D V++ AQ V S + P +T +V+ +GT+ +L A+
Sbjct: 63 VLHYGDLTDSSNLTRIIQEVQPDEVYNLGAQSHVAVSFESPEYTADVDAMGTLRLLEAIR 122
Query: 106 ----EGNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSG----EHYCKVFYQL 157
E + AS++ ++G +P RE P P SPY V+K+ +YC+ Y L
Sbjct: 123 LLGLEKKTRFYQASTSELFGLVQEIPQRETTPFYPRSPYAVAKLYAYWITVNYCEA-YGL 181
Query: 158 YGVPTVILRYFNVYGPRQSSAY-AGVISIFMERALRG-EPLVIFGDGKQSRDFVYVKDVV 215
Y ++ FN PR+ + I+ + +G + + G+ RD+ + KD V
Sbjct: 182 YACNGIL---FNHESPRRGETFVTRKITRGLANIAQGLDSCLYMGNIDSLRDWGHAKDYV 238
Query: 216 EANILVAEKRRAEGETFNVGTGRETTIIELAM------------------KIIELSSTSS 257
+ L+ ++ E E F + TG + ++ + + ++ + ST
Sbjct: 239 QLQWLMLQQE--EPEDFVIATGEQYSVRQFILWAAEDVGMQLRFEGKGVEEVAVVVSTKG 296
Query: 258 QILFSKPRPGDIRRSV-------ADIEKI--------KKLGFKPRYSLEE 292
+ L RPGD+ + A+++ + +KLG+KP ++ E
Sbjct: 297 E-LAPAVRPGDVVLRIDPRYFRPAEVDSLLGDASKAREKLGWKPSITVRE 345
>sp|Q06952|GMD1_VIBCH PROBABLE GDP-MANNOSE 4,6-DEHYDRATASE (GDP-D-MANNOSE DEHYDRATASE)
>gi|280159|pir||S28470 GDP-mannose 4,6-dehydratase
VC0243 [imported] - Vibrio cholerae (group O1 strain
N16961) >gi|48385|emb|CAA42136.1| (X59554)
oxidoreductase?,has homology to Salmonella typhimurium
RfbB [Vibrio cholerae] >gi|9654652|gb|AAF93419.1|
(AE004113) GDP-mannose 4,6-dehydratase [Vibrio cholerae]
>gi|1586119|prf||2203285C rfbD gene [Vibrio cholerae]
Length = 373
Score = 73.7 bits (178), Expect = 2e-12
Identities = 69/265 (26%), Positives = 118/265 (44%), Gaps = 24/265 (9%)
Query: 1 MRNKLIVVTGGAGFIGSHIAEALKEENDVVV-------------IDNLYSGKPENVPEGV 47
M K+ ++TG G GS++AE L E+ V +D+LY P
Sbjct: 1 MNKKVALITGITGQDGSYLAEFLLEKGYEVHGIKRRSSLFNTQRVDHLYKD-PHEEDVNF 59
Query: 48 KFIEADVRDYESIAEIVSSA--DYVFHEAAQISVEESVKDPVFTEEVNVIGTINILRALS 105
K D+ D ++ I++ D V++ AQ V S + P +T +V+ IGT+ +L A+
Sbjct: 60 KLHYGDLTDSSNLTRILAEVQPDEVYNLGAQSHVAVSFQSPEYTADVDAIGTLRLLEAIR 119
Query: 106 ----EGNGKLIFASSAAVYGEPTSLPIREDHPLNPISPYGVSKVSGEHYCKVFYQLYGVP 161
K AS++ +YG +P +E P P SPY V+K+ + + YG+
Sbjct: 120 FLGLTKKTKFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKMYAYWITINYRESYGIY 179
Query: 162 TVILRYFNVYGPRQSSAY-AGVISIFMERALRG-EPLVIFGDGKQSRDFVYVKDVVEANI 219
FN PR+ + I+ M +G E + G+ RD+ + KD V+
Sbjct: 180 ACNGILFNHESPRRGETFVTRKITRGMANIAQGLEKCLFMGNLDALRDWGHAKDYVKMQW 239
Query: 220 LVAEKRRAEGETFNVGTGRETTIIE 244
++ + + E F + TG + ++ E
Sbjct: 240 MMLQ--QDEPRDFVIATGVQYSVRE 262
>emb|CAA57106.1| (X81324) UDP-glucose 4-epimerase [Saccharomyces cerevisiae]
Length = 566
Score = 73.4 bits (177), Expect = 3e-12
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 28/221 (12%)
Query: 115 SSAAVYGE----PTSLPIREDHPLNPISPYGVSKVSGEHYCKVFY--QLYGVPTVILRYF 168
SSA VYG+ P +PI E+ PL P +PYG +K + E+ Y ILRYF
Sbjct: 1 SSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDLYNSDKKSWKFAILRYF 60
Query: 169 NVYGPRQSSAYA--------GVISIFMERAL-RGEPLVIFG------DGKQSRDFVYVKD 213
N G S ++ + A+ R E L IFG DG RD+++V D
Sbjct: 61 NPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRDGTPIRDYIHVVD 120
Query: 214 VVEANILVAEKRRAEGET------FNVGTGRETTIIELAMKIIELSSTSSQILFSKPRPG 267
+ + +I + A E +N+G+G+ +T+ E+ + S + R G
Sbjct: 121 LAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASGIDLPYKVTGRRAG 180
Query: 268 DIRRSVADIEKIKK-LGFKPRYSLEEGLLETWKWFKSRTLG 307
D+ A ++ K+ L ++ +E+ + WKW G
Sbjct: 181 DVLNLTAKPDRAKRELKWQTELQVEDSCKDLWKWTTENPFG 221
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.137 0.386
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113349764
Number of Sequences: 2977
Number of extensions: 4824458
Number of successful extensions: 15656
Number of sequences better than 1.0e-10: 446
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 429
Number of HSP's that attempted gapping in prelim test: 14030
Number of HSP's gapped (non-prelim): 499
length of query: 307
length of database: 189,106,746
effective HSP length: 58
effective length of query: 249
effective length of database: 154,394,500
effective search space: 38444230500
effective search space used: 38444230500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)