BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2147 (PAB2147) DE:ABC transporter, ATP-binding protein
(579 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75142 abc transporter, ATP-binding protein PAB2147 - Pyroc... 1121 0.0
pir||C71182 probable ABC transporter ATP-binding protein - Pyroc... 936 0.0
sp|Q9WYC4|Y288_THEMA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 359 4e-98
dbj|BAA96814.1| (AB040146) ABC transporter B [Thermus thermophilus] 353 3e-96
pir||F75142 abc transporter ATP-binding protein PAB2148 - Pyroco... 337 2e-91
pir||H69857 ABC transporter (ATP-binding protein) homolog yknU -... 335 6e-91
dbj|BAB10828.1| (AB016892) ABC transporter-like protein [Arabido... 334 1e-90
dbj|BAB04844.1| (AP001511) ABC transporter (ATP-binding protein)... 324 1e-87
pir||S72637 hypothetical ABC exporter component A - Thermoanaero... 324 2e-87
dbj|BAB04845.1| (AP001511) ABC transporter (ATP-binding protein)... 317 2e-85
pir||B71182 probable ABC transporter ATP-binding protein - Pyroc... 317 2e-85
sp|P54719|YFIC_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 314 2e-84
pir||F75321 ABC transporter, ATP-binding protein, MDR family - D... 312 9e-84
emb|CAB66302.1| (AL136519) ABC transporter protein, ATP-binding ... 310 2e-83
pir||A69858 ABC transporter (ATP-binding protein) homolog yknV -... 309 4e-83
pir||S72638 hypothetical ABC exporter component B - Thermoanaero... 306 5e-82
pir||A75590 ABC transporter, ATP-binding protein - Deinococcus r... 305 7e-82
dbj|BAA96813.1| (AB040146) ABC transporter A [Thermus thermophilus] 305 7e-82
pir||E72396 ABC transporter, ATP-binding protein - Thermotoga ma... 305 7e-82
gb|AAK43114.1| ABC transporter, ATP binding protein [Sulfolobus ... 304 1e-81
gb|AAG15222.1|AF288462_2 (AF288462) AbcA [Chloroflexus aurantiacus] 303 4e-81
emb|CAB05917.1| (Z83327) transport-associated protein [Salmo salar] 298 1e-79
dbj|BAB04660.1| (AP001510) ABC transporter (ATP-binding protein)... 297 2e-79
pir||C72275 ABC transporter, ATP-binding protein - Thermotoga ma... 297 2e-79
pir||S75352 ABC-type transport protein slr2019 - Synechocystis s... 296 3e-79
pir||S77337 ABC-type transport protein sll1725 - Synechocystis s... 296 4e-79
pir||G69815 ABC transporter (ATP-binding protein) homolog ygaD -... 295 1e-78
gb|AAD53033.1|AF115536_1 (AF115536) TAP1 protein [Oncorhynchus m... 294 1e-78
pir||G75321 ABC transporter, ATP-binding protein, MsbA family - ... 293 3e-78
pir||B83022 transport protein MsbA PA4997 [imported] - Pseudomon... 292 6e-78
dbj|BAB04534.1| (AP001509) ABC transporter (ATP-binding protein)... 290 3e-77
gb|AAB52482.1| (U97407) Contains similarity to Pfam domain: PF00... 289 6e-77
gi|9955966 ATP-binding cassette, sub-family B, member 9, isoform... 289 7e-77
gi|11560034 TAP-like ABC transporter [Rattus norvegicus] >gi|604... 288 9e-77
dbj|BAA97990.2| (AB045382) TAPL [Mus musculus] 288 9e-77
pir||T27215 hypothetical protein Y57G11C.1 - Caenorhabditis eleg... 288 1e-76
gi|9845230 ATP-binding cassette, sub-family B, member 9 [Mus mus... 288 1e-76
pir||S76668 hypothetical protein - Synechocystis sp. (strain PCC... 287 2e-76
pir||G70837 probable ABC transporter Rv0194 - Mycobacterium tube... 287 2e-76
dbj|BAB06054.1| (AP001515) ABC transporter (ATP-binding protein)... 285 8e-76
pir||A69829 ABC transporter (ATP-binding protein) homolog yheI -... 285 1e-75
gb|AAG18746.1| (AE004979) ABC transport protein; Trp1 [Halobacte... 284 1e-75
dbj|BAB07610.1| (AP001520) ABC transporter (ATP-binding protein)... 284 2e-75
gb|AAF67494.1|AF170880_1 (AF170880) NovA [Streptomyces spheroides] 283 3e-75
pir||T32865 hypothetical protein ZK484.2 - Caenorhabditis elegan... 283 4e-75
sp|P77265|MDLA_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 282 7e-75
sp|Q11047|YC72_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 279 6e-74
pir||S58356 pepT protein - Staphylococcus epidermidis >gi|212659... 279 6e-74
emb|CAB88985.1| (AL353864) putative ABC-transport protein. [Stre... 279 6e-74
emb|CAB76004.1| (AL157916) putative ABC transporter [Streptomyce... 278 1e-73
emb|CAC13096.1| (AL445503) putative ABC transporter ATP-binding ... 277 2e-73
sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 277 3e-73
gb|AAF48177.1| (AE003489) CG1824 gene product [Drosophila melano... 277 3e-73
sp|P45861|YWJA_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 273 3e-72
pir||A75554 ABC transporter, ATP-binding protein, MsbA family - ... 273 3e-72
emb|CAB05918.1| (Z83328) transport-associated protein [Salmo salar] 273 4e-72
dbj|BAB04876.1| (AP001511) ABC transporter (ATP-binding protein)... 273 5e-72
dbj|BAA92038.1| (AK002018) unnamed protein product [Homo sapiens] 272 6e-72
gb|AAG25076.1|AF273216_1 (AF273216) ABC transporter RzcB [Rhizob... 272 8e-72
emb|CAB69752.1| (AL137187) putative ABC transporter [Streptomyce... 271 1e-71
emb|CAB60586.1| (AL117200) contains similarity to Pfam domain: P... 271 2e-71
pir||T31617 hypothetical protein Y50E8A.m - Caenorhabditis elegans 271 2e-71
dbj|BAB04432.1| (AP001509) ABC transporter (ATP-binding protein)... 271 2e-71
pir||H72425 ABC transporter, ATP-binding protein - Thermotoga ma... 271 2e-71
sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA... 270 2e-71
gb|AAA91199.1| (L76468) ABC-transporter [Gorilla gorilla] 270 2e-71
gb|AAC12903.1| (L21205) peptide transporter [Homo sapiens] >gi|3... 270 2e-71
gb|AAG11416.1|AF263455_1 (AF263455) TagA [Dictyostelium discoideum] 270 2e-71
gb|AAC12905.1| (L21207) peptide transporter [Homo sapiens] 270 3e-71
gb|AAD55753.1|AF108387_1 (AF108387) transporter associated with ... 270 4e-71
gi|6005804 ATP-binding cassette, sub-family B, member 8; mitocho... 270 4e-71
pir||T34038 hypothetical protein F43E2.4 - Caenorhabditis elegan... 269 7e-71
sp|Q03518|TAP1_HUMAN ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (PEPTI... 268 1e-70
gi|9665248 ATP-binding cassette, sub-family B, member 2; antigen... 268 1e-70
gb|AAA91198.1| (L76470) ABC-transporter [Gorilla gorilla] 268 1e-70
pir||T31078 probable ABC-transporter TycE - Brevibacillus brevis... 268 1e-70
dbj|BAB04877.1| (AP001511) ABC transporter (ATP-binding protein)... 268 1e-70
gb|AAC12906.1| (L21208) peptide transporter [Homo sapiens] 268 2e-70
gi|9506367 ATP-binding cassette, sub-family B, member 12; Abc-mi... 268 2e-70
pir||S77239 ABC-type transport protein sll1276 - Synechocystis s... 267 3e-70
dbj|BAB06055.1| (AP001515) ABC transporter (ATP-binding protein)... 266 3e-70
pir||T31073 multidrug resistance p-glycoprotein - nematode (Haem... 265 1e-69
pir||F82198 probable toxin secretion transporter VC1446 [importe... 265 1e-69
gb|AAA91200.1| (L76469) ABC-transporter [Gorilla gorilla] 265 1e-69
emb|CAA62898.1| (X91786) ATP-binding cassette transporter A [Sta... 265 1e-69
gb|AAB88659.1| (U62935) multidrug resistance protein 2 [Aspergil... 265 1e-69
pir||T13416 hypothetical protein 171D11.2 - fruit fly (Drosophil... 264 2e-69
gb|AAF71763.1|AF263912_2 (AF263912) NysG [Streptomyces noursei] 264 2e-69
gb|AAF45509.1| (AE003417) EG:171D11.2 gene product [Drosophila m... 264 2e-69
emb|CAA71282.1| (Y10233) Tap1 protein [Rattus norvegicus] 264 2e-69
emb|CAA40742.1| (X57523) mtp1 [Rattus norvegicus] 263 3e-69
sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) >gi|1115... 263 3e-69
pir||D70031 ABC transporter (ATP-binding protein) homolog yvcC -... 263 3e-69
emb|CAA71281.1| (Y10232) Tap1 protein [Rattus norvegicus] 263 3e-69
pir||G71731 mitochondrial transporter atm1 precursor (atm1) RP20... 262 7e-69
pir||I84547 mdl protein - Escherichia coli >gi|146801|gb|AAC3687... 262 9e-69
emb|CAA71279.1| (Y10230) Tap1 protein [Rattus norvegicus] >gi|17... 262 9e-69
emb|CAA71284.1| (Y10235) Tap1 protein [Rattus norvegicus] 261 1e-68
pir||B83507 probable ATP-binding/permease fusion ABC transporter... 261 1e-68
sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA... 261 2e-68
gi|6324985 ATP-binding cassette (ABC) transporter family member;... 261 2e-68
pir||S77459 ABC-type transport protein slr1149 - Synechocystis s... 261 2e-68
pir||T31077 probable ABC-transporter TycD - Brevibacillus brevis... 261 2e-68
gb|AAC02113.1| (AF045016) multidrug resistance p-glycoprotein [C... 261 2e-68
gb|AAA20682.1| (L16959) Mdl2p [Saccharomyces cerevisiae] 260 3e-68
gb|AAB41965.1| (U60021) TAP1-f [Mus musculus] 260 3e-68
gb|AAB41966.1| (U60022) TAP1-k [Mus musculus] 260 3e-68
gb|AAB58721.2| (AF001154) TAP1 [Mesocricetus auratus] 260 3e-68
gb|AAD53035.1|AF115538_1 (AF115538) TAP2B protein [Oncorhynchus ... 259 4e-68
gb|AAB58723.2| (AF001156) TAP1 [Mesocricetus auratus] 259 4e-68
pir||S75806 hemolysin secretion protein hlyB - Synechocystis sp.... 259 6e-68
gb|AAF81747.1| (AF269224) his-tagged-multidrug resistance glycop... 259 6e-68
gb|AAA59575.1| (M14758) P-glycoprotein [Homo sapiens] 259 8e-68
pir||JC4554 ABC-type transporter homolog - Staphylococcus aureus... 258 1e-67
gi|7305539 ATP-binding cassette, sub-family B, member 2; ATP dep... 258 1e-67
dbj|BAA87071.1| (AB029153) multi-drug resistance related mRNA [F... 258 1e-67
pir||D82146 transport ATP-binding protein MsbA VC1878 [imported]... 258 1e-67
sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 258 1e-67
sp|P75094|Y015_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 258 1e-67
sp|P57551|MDLA_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 258 1e-67
pir||A37779 histocompatibility antigen modifier 1 - mouse >gi|19... 257 2e-67
gb|AAB41964.1| (U60020) TAP1-g7 [Mus musculus] >gi|1399911|gb|AA... 257 2e-67
gi|6679297 P glycoprotein 2 [Mus musculus] >gi|126929|sp|P21440|... 257 2e-67
pir||T02187 hypothetical protein F14M4.17 - Arabidopsis thaliana... 257 2e-67
gi|9961244 ATP-binding cassette, sub-family B, member 10 [Homo s... 257 2e-67
gi|11419215 ATP-binding cassette, sub-family B (MDR/TAP), member... 256 4e-67
gi|11425328 ATP-binding cassette, sub-family B, member 10 [Homo ... 256 4e-67
emb|CAB76005.1| (AL157916) putative ABC transporter [Streptomyce... 256 4e-67
pir||S60182 ATP-binding transport protein exsA - Rhizobium melil... 256 4e-67
gi|4505769 ATP-binding cassette, sub-family B (MDR/TAP), member ... 256 4e-67
gb|AAD22644.1|AC007138_8 (AC007138) P-glycoprotein-like protein ... 256 4e-67
gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo sa... 256 4e-67
dbj|BAB02129.1| (AP000386) P-glycoprotein; multi-drug resistance... 256 4e-67
gb|AAG33617.1|AF308472_1 (AF308472) ATP-binding cassette half-tr... 256 4e-67
pir||DVHY1C multidrug resistance protein 1 - Chinese hamster >gi... 256 5e-67
gb|AAA37005.1| (M59254) p-glycoprotein [Cricetulus sp.] 256 5e-67
emb|CAA75922.1| (Y15990) P-glycoprotein-like protein [Arabidopsi... 256 5e-67
sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 256 7e-67
sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROT... 256 7e-67
pir||T40790 probable permease - fission yeast (Schizosaccharomyc... 256 7e-67
gb|AAF69007.1|AF257746_1 (AF257746) multidrug resistance protein... 256 7e-67
sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEI... 256 7e-67
gb|AAB41963.1| (U60019) TAP1-b [Mus musculus] >gi|2555195|gb|AAB... 255 9e-67
dbj|BAB10822.1| (AB019223) multidrug resistance p-glycoprotein [... 255 9e-67
gi|6981354 P-glycoprotein 3/ multidrug resistance 2 [Rattus norv... 255 1e-66
gb|AAD01950.1| (AF033015) ABC transporter homolog Z [Listeria mo... 255 1e-66
pir||A75282 ABC transporter, ATP-binding protein, MsbA family - ... 254 2e-66
pir||T48007 P-glycoprotein homolog T17J13.110 [similarity] - Ara... 254 2e-66
gb|AAC44070.1| (U51197) unknown [Sphingomonas sp. S88] 254 2e-66
emb|CAA42178.1| (X59615) HAM-1 [Mus musculus] 254 3e-66
emb|CAA08835.1| (AJ009799) ABC transporter protein [Gallus gallus] 254 3e-66
dbj|BAA96612.1| (AP002482) Similar to Arabidopsis thaliana chrom... 253 3e-66
pir||B71676 probable ABC transporter msbA2 - Rickettsia prowazek... 253 4e-66
pir||T17482 ABC-type transport protein homolog - Amycolatopsis o... 252 6e-66
sp|P55469|Y4GM_RHISN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEI... 252 1e-65
dbj|BAA34383.1| (AB019513) ABC transporter [Streptomyces coelico... 252 1e-65
emb|CAC14944.1| (AL449216) putative ABC transporter ATP-binding ... 252 1e-65
pir||JE0248 ATP-binding cassette half-transporter - rat >gi|2982... 251 1e-65
gb|AAD15830.1| (AF062387) TAP2 protein [Xenopus laevis] 251 1e-65
gi|6755046 ATP-binding cassette, sub-family B, member 1; P glyco... 251 2e-65
pir||T21266 hypothetical protein F22E10.1 - Caenorhabditis elega... 251 2e-65
sp|P47261|Y015_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 250 2e-65
sp|O14286|YETI_SCHPO PUTATIVE ABC TRANSPORTER C8C9.18 IN CHROMOS... 250 2e-65
gb|AAB09036.1| (U68242) TxpA [Bartonella bacilliformis] 250 3e-65
emb|CAB69751.1| (AL137187) putative ABC transporter [Streptomyce... 250 3e-65
gi|6755048 ATP-binding cassette, sub-family B, member 4; P glyco... 249 5e-65
pir||T22813 hypothetical protein F57A10.3 - Caenorhabditis elega... 249 5e-65
gb|AAG10628.1|AC022521_6 (AC022521) Putative ABC transporter [Ar... 249 5e-65
pir||T28150 probable ATP-binding cassette transporter TAP1 - chi... 248 1e-64
gb|AAD22645.1|AC007138_9 (AC007138) putative P-glycoprotein-like... 247 2e-64
gb|AAD49436.1|AF083642_1 (AF083642) P-glycoprotein [Onchocerca v... 247 3e-64
pir||DVMS1A multidrug resistance protein 1a - mouse (fragment) >... 246 4e-64
sp|Q02592|HMT1_SCHPO HEAVY METAL TOLERANCE PROTEIN PRECURSOR >gi... 246 6e-64
gb|AAG10627.1|AC022521_5 (AC022521) Putative ABC transporter [Ar... 245 1e-63
pir||S25198 vacuolar membrane protein HMT1 - fission yeast (Sch... 245 1e-63
pir||T06165 multidrug resistance protein 1 homolog - barley >gi|... 243 3e-63
pir||A35391 hetA protein - Anabaena sp 243 4e-63
pir||A42150 P-glycoprotein pgp1 - Arabidopsis thaliana >gi|38498... 243 5e-63
gb|AAA66476.1| (L26286) SMDR1 [Schistosoma mansoni] 243 5e-63
pir||E82539 ABC transporter ATP-binding protein XF2582 [imported... 243 5e-63
sp|Q03727|COMA_STRPN TRANSPORT ATP-BINDING PROTEIN COMA >gi|5207... 242 6e-63
pir||A39203 comA protein - Streptococcus pneumoniae 242 9e-63
sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49 (P-... 242 9e-63
gb|AAF58437.1| (AE003820) Mdr49 gene product [Drosophila melanog... 242 9e-63
pir||T19982 hypothetical protein C47A10.1 - Caenorhabditis elega... 242 1e-62
pir||C81352 lipid export ABC transport protein Cj0803 [imported]... 242 1e-62
sp|Q10418|MESD_LEUME MESENTERICIN Y105 TRANSPORT ATP-BINDING PRO... 241 2e-62
emb|CAA88940.2| (Z49126) contains similarity to Pfam domain: PF0... 241 2e-62
gb|AAB49750.1| (U63741) multidrug resistance protein LmrA [Lacto... 240 4e-62
sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 238 1e-61
pir||T23476 hypothetical protein K08E7.9 - Caenorhabditis elegan... 238 1e-61
gb|AAD53034.1|AF115537_1 (AF115537) TAP2 protein [Oncorhynchus m... 238 1e-61
pir||B64655 multidrug resistance protein - Helicobacter pylori (... 238 1e-61
pir||DVHY2C multidrug resistance protein 2 - Chinese hamster (fr... 238 2e-61
gb|AAB51079.1| (L40491) leucocin A translocator [Leuconostoc gel... 237 3e-61
sp|P18767|NDVA_RHIME BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTE... 236 4e-61
gb|AAG01549.1|AF291822_1 (AF291822) multidrug resistance protein... 236 5e-61
sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-... 235 1e-60
gb|AAB88657.1| (U62933) multidrug resistance protein 1 [Aspergil... 235 1e-60
pir||T21269 hypothetical protein F22E10.4 - Caenorhabditis elega... 235 1e-60
gb|AAF50669.1| (AE003563) Mdr65 gene product [Drosophila melanog... 235 1e-60
pir||T22090 hypothetical protein F42E11.1 - Caenorhabditis elega... 235 1e-60
emb|CAA64189.1| (X94434) ABC-transporter PlnG [Lactobacillus pla... 234 2e-60
gb|AAD43626.1|AF071411_1 (AF071411) multidrug resistance protein... 234 2e-60
pir||T26313 hypothetical protein W09D6.6 - Caenorhabditis elegan... 234 2e-60
gb|AAD02044.1| (AF035964) ATP-binding protein A [Brucella abortus] 233 3e-60
gb|AAF50670.1| (AE003563) CG10226 gene product [Drosophila melan... 233 4e-60
pir||T48418 ABC transporter-like protein - Arabidopsis thaliana ... 233 6e-60
pir||T21268 hypothetical protein F22E10.3 - Caenorhabditis elega... 231 1e-59
gb|AAD25925.1|AF082072_1 (AF082072) ABC transporter protein AtrC... 231 1e-59
gb|AAB69130.1| (U63320) P-glycoprotein [Leishmania tropica] 231 2e-59
pir||T41534 leptomycin B resistance protein, ABC transporter - f... 231 2e-59
emb|CAB05915.1| (Z83325) transport-associated protein [Salmo salar] 231 2e-59
emb|CAA94219.2| (Z70268) Similarity to C.elegans p-glycoprotein ... 231 2e-59
pir||T25082 hypothetical protein T21E8.2 - Caenorhabditis elegans 231 2e-59
dbj|BAB02613.1| (AP002043) P-glycoprotein; multi-drug resistance... 230 3e-59
pir||T22094 hypothetical protein ZK455.7 - Caenorhabditis elegan... 229 5e-59
sp|P34713|MDR3_CAEEL MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT... 229 8e-59
sp|P36619|PMD1_SCHPO LEPTOMYCIN B RESISTANCE PROTEIN PMD1 >gi|10... 229 8e-59
gb|AAB37564.1| (U40139) ComA [Streptococcus gordonii] 229 8e-59
pir||T18939 hypothetical protein C05A9.1 - Caenorhabditis elegan... 227 2e-58
pir||H82351 probable hemolysin secretion ATP-binding protein VC0... 227 3e-58
dbj|BAB13177.1| (AP001119) mdlB [Buchnera sp. APS] 227 3e-58
sp|P57552|MDLB_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 227 3e-58
pir||F82391 ABC transporter, ATP-binding protein VCA0996 [import... 226 7e-58
sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 225 9e-58
gb|AAA02977.1| (L01572) P-glycoprotein [Leishmania donovani] 224 2e-57
gi|4502457 ATP-binding cassette, sub-family B (MDR/TAP), member ... 224 2e-57
gb|AAD28285.1|AF136523_1 (AF136523) bile salt export pump [Homo ... 224 2e-57
gi|11430459 ATP-binding cassette, sub-family B (MDR/TAP), member... 224 3e-57
dbj|BAA76299.1| (AB003329) LAMDR1 [Leishmania amazonensis] 222 8e-57
pir||T29110 multidrug resistance protein 1 - Aureobasidium pullu... 222 1e-56
sp|P18768|CHVA_AGRTU BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTE... 221 1e-56
gb|AAF71764.1|AF263912_3 (AF263912) NysH [Streptomyces noursei] 221 1e-56
pir||JG0166 LaMDR1 protein - Leishmania mexicana amazonensis 220 2e-56
pir||T42842 bile salt transport protein, ATP-dependent - rat >gi... 219 7e-56
pir||T42228 P-glycoprotein sister - rat >gi|3273484|gb|AAC24753.... 219 7e-56
gi|11038656 ATP-binding cassette, sub-family B, member 11; bile ... 219 9e-56
pir||T18940 multidrug resistance protein homolog - Caenorhabditi... 217 2e-55
pir||A41464 hemolysin secretion protein CylB - Enterococcus faec... 217 3e-55
pir||D72083 transport ATP binding protein - Chlamydophila pneumo... 217 3e-55
gb|AAF73656.1| (AE002196) ABC transporter, ATP-binding protein [... 217 3e-55
emb|CAA94220.2| (Z70268) Similarity to C.elegans p-glycoprotein ... 213 4e-54
gb|AAD29692.1|AF135793_1 (AF135793) sister of P-glycoprotein [Fu... 212 9e-54
gb|AAF65552.1|AF249879_1 (AF249879) liver bile salt export pump ... 212 1e-53
emb|CAB69672.1| (AL137165) probable ABC transporter protein, ATP... 210 5e-53
pir||T30293 ABC transport protein homolog - Salmonella typhi >gi... 209 6e-53
gb|AAF73568.1| (AE002322) ABC transporter, ATP-binding protein [... 208 1e-52
pir||H83243 probable ATP-binding/permease fusion ABC transporter... 206 7e-52
pir||E71536 probable transport ATP binding protein - Chlamydia t... 203 3e-51
gb|AAB40205.1| (U82664) multidrug resistance-like ATP-binding pr... 196 8e-49
sp|P75706|MDLB_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 196 8e-49
pir||S76856 hypothetical protein - Synechocystis sp. (strain PCC... 192 1e-47
emb|CAB97204.1| (AJ277881) conjugate export pump protein [Rattus... 190 3e-47
gb|AAB09422.1| (U49248) canalicular multispecific organic anion ... 189 6e-47
gi|6678848 ATP-binding cassette, sub-family C, member 1; multipl... 189 1e-46
gb|AAA02976.1| (L06062) multi drug resistance P-glycoprotein [Le... 189 1e-46
dbj|BAA28955.1| (AB010467) multidrug resistance-associated prote... 187 2e-46
sp|O88563|MRP3_RAT CANALICULAR MULTISPECIFIC ORGANIC ANION TRANS... 187 3e-46
gi|4557481 ATP-binding cassette, sub-family C (CFTR/MRP), member... 187 4e-46
gi|11430957 ATP-binding cassette, sub-family C (CFTR/MRP), membe... 187 4e-46
sp|P47260|Y014_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 184 2e-45
sp|P75095|Y014_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 184 2e-45
pir||S71841 multidrug resistance protein, canalicular - human >g... 184 3e-45
emb|CAB45309.1| (AJ132244) multidrug resistance protein 2 (MRP2)... 184 3e-45
gb|AAF52639.1| (AE003620) CG7806 gene product [Drosophila melano... 184 3e-45
gi|11184219 ATP-binding cassette, sub-family C, member 2; canali... 183 3e-45
gb|AAB83979.1| (AF022853) multidrug resistance protein [Homo sap... 183 4e-45
gb|AAB83980.1| (AF022853) multidrug resistance protein [Homo sap... 183 4e-45
gb|AAB83981.1| (AF022853) multidrug resistance protein [Homo sap... 183 4e-45
pir||DVHUAR multidrug resistance protein (cell line H69AR) - human 183 4e-45
gi|9955950 ATP-binding cassette, sub-family C, member 1, isoform... 183 4e-45
gi|9955952 ATP-binding cassette, sub-family C, member 1, isoform... 183 4e-45
gi|9955954 ATP-binding cassette, sub-family C, member 1, isoform... 183 4e-45
gi|9955958 ATP-binding cassette, sub-family C, member 1, isoform... 183 4e-45
gi|9955960 ATP-binding cassette, sub-family C, member 1, isoform... 183 4e-45
gi|11430314 ATP-binding cassette, sub-family C, member 1, isofor... 183 4e-45
gb|AAB83982.1| (AF022853) multidrug resistance protein [Homo sap... 183 4e-45
gi|11430316 ATP-binding cassette, sub-family C, member 1, isofor... 183 4e-45
gi|11430318 ATP-binding cassette, sub-family C, member 1, isofor... 183 4e-45
gi|11430320 ATP-binding cassette, sub-family C, member 1, isofor... 183 4e-45
gi|4826838 ATP-binding cassette, sub-family C, member 1, isoform... 183 4e-45
gi|11430322 ATP-binding cassette, sub-family C, member 1, isofor... 183 4e-45
gi|11430324 ATP-binding cassette, sub-family C, member 1, isofor... 183 4e-45
sp|Q28689|MRP2_RABIT CANALICULAR MULTISPECIFIC ORGANIC ANION TRA... 182 7e-45
gi|6978669 canalicular multispecific organic anion transporter [... 181 2e-44
dbj|BAA13016.1| (D86086) canalicular multispecific organic anion... 181 2e-44
gi|6322640 ABC transporter, glycoprotein, component of a-factor ... 180 4e-44
prf||1512309A multidrug resistance P glycoprotein [Saccharomyces... 180 4e-44
gb|AAB61134.1| (U61158) GdmT [Staphylococcus gallinarum] 180 5e-44
sp|Q10185|YAWB_SCHPO PROBABLE ATP-DEPENDENT PERMEASE C3F10.11C >... 177 3e-43
dbj|BAA28146.1| (AB010887) multidrug resistance-associated prote... 177 3e-43
gb|AAD01430.1| (AF009670) MRP3 [Homo sapiens] 177 3e-43
gi|9955970 ATP-binding cassette, sub-family C, member 3, isoform... 177 3e-43
emb|CAA76658.2| (Y17151) multidrug resistance protein 3 (ABCC3) ... 177 3e-43
gi|11434386 ATP-binding cassette, sub-family C, member 3, isofor... 177 3e-43
sp|Q11018|YD48_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 176 6e-43
pir||JE0336 canalicular multispecific organic anion transporter ... 176 7e-43
pir||T01369 multidrug-resistance protein homolog T29F13.13 - Ara... 174 2e-42
gb|AAC49988.1| (AF014960) multidrug resistance-associated protei... 173 6e-42
gb|AAC04245.1| (AF020288) MgATP-energized glutathione S-conjugat... 173 6e-42
gb|AAF19743.1|AC009917_2 (AC009917) Similar to gb|AF008124 Arabi... 171 1e-41
gb|AAB71756.1| (U83659) multidrug resistance-associated protein ... 168 1e-40
gb|AAG28284.1|AC025295_4 (AC025295) glutathione S-conjugate tran... 167 3e-40
gb|AAF52648.1| (AE003620) CG7627 gene product [Drosophila melano... 167 4e-40
sp|O88269|MRP6_RAT MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 6 (MR... 166 5e-40
gb|AAB67319.1| (AF008124) glutathione S-conjugate transporting A... 166 6e-40
gb|AAC04246.1| (AF020289) MgATP-energized glutathione S-conjugat... 166 8e-40
gb|AAA83299.1| (U41554) Contains similarity to Pfam domain: PF00... 164 2e-39
gb|AAB07022.1| (U66261) multidrug resistance related protein 2 [... 164 2e-39
gb|AAF53736.2| (AE003661) CG17338 gene product [Drosophila melan... 164 2e-39
gi|6715561 ATP-binding cassette, sub-family C, member 6; anthrac... 164 2e-39
pir||T20903 hypothetical protein F14F4.3b - Caenorhabditis elega... 164 2e-39
pir||T20904 hypothetical protein F14F4.3a - Caenorhabditis elega... 164 2e-39
pir||H72270 ABC transporter, ATP-binding protein - Thermotoga ma... 162 7e-39
gi|9055156 multidrug resistance-associated protein-6 [Mus muscul... 162 1e-38
gb|AAC15784.1| (U91318) Multiple drug resistance gene MRP1 (5' p... 161 3e-38
gb|AAD51293.1|AF168791_1 (AF168791) multi-specific organic anion... 159 1e-37
emb|CAB91574.1| (AL356012) ABC multidrug or ion efflux transport... 157 2e-37
pir||B71696 probable transport ATP-binding protein msbA (msbA1) ... 157 3e-37
gb|AAD28497.1|AF061787_4 (AF061787) McjD [Escherichia coli] 157 3e-37
gb|AAD31550.2|U41554_5 (U41554) C. elegans multidrug resistance ... 154 2e-36
pir||T21219 hypothetical protein F21G4.2 - Caenorhabditis elegan... 154 3e-36
gb|AAD38185.1|AF154001_1 (AF154001) MRP3s1 protein [Homo sapiens] 154 3e-36
gb|AAB07021.1| (U66260) multidrug resistance related protein 1 [... 153 5e-36
gb|AAG28282.1|AC025295_2 (AC025295) ABC transporter, putative [A... 152 8e-36
gi|6321720 Yor1p [Saccharomyces cerevisiae] >gi|1730876|sp|P5304... 152 1e-35
gi|11038666 ATP-binding cassette, sub-family C, member 9, isofor... 152 1e-35
pir||S57561 strV protein - Streptomyces glaucescens >gi|2127536|... 152 1e-35
gb|AAF56870.1| (AE003768) CG11898 gene product [Drosophila melan... 150 3e-35
dbj|BAA13892.1| (D89231) similar to Saccharomyces cerevisiae met... 149 9e-35
pir||C83412 probable ATP-binding/permease fusion ABC transporter... 148 2e-34
pir||T33559 hypothetical protein W04C9.1 - Caenorhabditis elegan... 146 6e-34
pir||F71844 ABC transporter, ATP-binding protein - Helicobacter ... 145 2e-33
emb|CAA65019.1| (X95715) anthracycline resistance associated pro... 144 2e-33
pir||T50210 probable ABC transporter [imported] - fission yeast ... 144 3e-33
gi|6321752 ABC transporter; Yhl035cp [Saccharomyces cerevisiae] ... 139 8e-32
pir||T27408 hypothetical protein Y75B8A.26 - Caenorhabditis eleg... 137 4e-31
prf||1703419A MHC II Y3 gene [Homo sapiens] 134 3e-30
emb|CAA40740.1| (X57521) Y3 [Homo sapiens] 134 3e-30
pir||T18343 P-glycoprotein - Sauroleishmania tarentolae >gi|4603... 133 6e-30
gb|AAD33775.1|AF139177_2 (AF139177) putative ATP binding membran... 131 3e-29
sp|P36028|YK83_YEAST PROBABLE ATP-DEPENDENT PERMEASE YKR103W/YKR... 130 4e-29
gb|AAA21388.1| (U03771) potential ATP-binding membrane transport... 128 2e-28
pir||T35182 probable ABC-type transport protein ramA - Streptomy... 128 2e-28
pir||DVLNS multidrug resistance protein - Leishmania tarentolae 126 7e-28
sp|P21441|MDR_LEITA MULTIDRUG RESISTANCE PROTEIN (P-GLYCOPROTEIN... 125 1e-27
gb|AAC95142.1| (AF075600) ABC translocator [Brochothrix campestris] 117 4e-25
dbj|BAB06693.1| (AP001517) alkylphosphonate ABC tranporter (ATP-... 115 1e-24
gi|6322957 Ykr104wp [Saccharomyces cerevisiae] >gi|539332|pir||S... 113 4e-24
sp|P44531|AFUC_HAEIN PUTATIVE FERRIC TRANSPORT ATP-BINDING PROTE... 109 8e-23
dbj|BAB04859.1| (AP001511) sugar ABC transportor (ATP-binding pr... 108 2e-22
gb|AAC41271.1| (AF000271) cystic fibrosis transmembrane conducta... 107 4e-22
pir||T30295 P-glycoprotein - Trypanosoma cruzi >gi|1150650|emb|C... 107 4e-22
sp|P94360|MSMX_BACSU PROBABLE MULTIPLE SUGAR-BINDING TRANSPORT A... 106 5e-22
dbj|BAB04005.1| (AP001508) ABC transporter (ATP-binding protein)... 104 4e-21
dbj|BAB04472.1| (AP001509) ABC transporter (ATP-binding protein)... 101 2e-20
dbj|BAB06418.1| (AP001516) ABC transporter (ATP-binding protein)... 99 2e-19
pir||S74597 ABC-type transport protein sll1041 - Synechocystis s... 96 1e-18
emb|CAC12530.1| (AL445067) ferrichrome ABC transporter (ATP-bind... 96 1e-18
emb|CAB76078.1| (AL157953) putative ABC transporter ATP-binding ... 94 4e-18
dbj|BAB07632.1| (AP001520) ABC transporter (ATP-binding protein)... 92 2e-17
emb|CAB60755.1| (Y18641) ATP-binding protein [Staphylococcus aur... 90 5e-17
gb|AAK41557.1| Antibiotic ABC transporter, ATP binding protein [... 88 2e-16
gb|AAD41066.1|AF128999_2 (AF128999) SitB [Salmonella typhimurium] 85 2e-15
pir||A70001 ABC transporter (ATP-binding protein) homolog ytsC -... 85 2e-15
emb|CAB88481.1| (AL353816) putative ABC transport system ATP-bin... 85 3e-15
emb|CAB93444.1| (AL357591) putative ABC transporter ATP-binding ... 84 3e-15
pir||C71645 ferric transport ATP-binding protein (afuC) RP834 - ... 83 6e-15
pir||G72750 probable ABC transporter ATP-binding protein APE0532... 83 6e-15
sp|P23703|NODI_RHILO NODULATION ATP-BINDING PROTEIN I >gi|95215|... 82 2e-14
dbj|BAB03338.1| (AB035453) ABC transporter [Staphylococcus aureus] 82 2e-14
pir||S74420 phosphate transport ATP-binding protein pstB-2 - Syn... 79 1e-13
pir||E75444 branched-chain amino acid ABC transporter, ATP-bindi... 77 6e-13
sp|P08531|ARAG_ECOLI L-ARABINOSE TRANSPORT ATP-BINDING PROTEIN A... 76 1e-12
emb|CAC12200.1| (AL445066) ABC transporter ATP-binding protein r... 73 1e-11
>pir||G75142 abc transporter, ATP-binding protein PAB2147 - Pyrococcus abyssi
(strain Orsay) >gi|5457732|emb|CAB49222.1| (AJ248284)
ABC transporter, ATP-binding protein [Pyrococcus abyssi]
Length = 579
Score = 1121 bits (2867), Expect = 0.0
Identities = 579/579 (100%), Positives = 579/579 (100%)
Query: 1 MRKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAI 60
MRKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAI
Sbjct: 1 MRKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAI 60
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI
Sbjct: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY
Sbjct: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM
Sbjct: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI
Sbjct: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSF 360
GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSF
Sbjct: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSF 360
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ
Sbjct: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ
Sbjct: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV
Sbjct: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGVYGG
Sbjct: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
>pir||C71182 probable ABC transporter ATP-binding protein - Pyrococcus
horikoshii >gi|3258167|dbj|BAA30850.1| (AP000007) 580aa
long hypothetical ABC transporter ATP-binding protein
[Pyrococcus horikoshii]
Length = 580
Score = 936 bits (2393), Expect = 0.0
Identities = 467/575 (81%), Positives = 525/575 (91%)
Query: 1 MRKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAI 60
M S+ QL RLLSYLR + HF+ G+ L++LMSYTN ++PVLIRNAIDKG+ T Y VA
Sbjct: 1 MDGSLRQLERLLSYLREYRWHFIGGIGLVLLMSYTNGVIPVLIRNAIDKGIVTKKYSVAF 60
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
YGLLILLV V NG+FS GRYLLVK+AQ+AVYY+RMDAF+AIQRH MEFFDKTFSGQLI
Sbjct: 61 NYGLLILLVAVFNGIFSFTGRYLLVKSAQHAVYYIRMDAFKAIQRHRMEFFDKTFSGQLI 120
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
SRITNDTERITRFLSFR+RM +YSIFLI +SLYYM+RMN+ L++VAL TIA+VV LNTTY
Sbjct: 121 SRITNDTERITRFLSFRIRMFVYSIFLIAVSLYYMIRMNVFLSLVALGTIAVVVLLNTTY 180
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
A KVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEEN+Q KFS+ENE LYSLN+ A+
Sbjct: 181 ATKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENIQEKFSKENENLYSLNIDAI 240
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
KITALYGNAPFL+LGLAMS M YYGGKAII TLTVGELVAFLTYMLTMMWPLRALGFTI
Sbjct: 241 KITALYGNAPFLILGLAMSAMLYYGGKAIIAKTLTVGELVAFLTYMLTMMWPLRALGFTI 300
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSF 360
GDIQRSLAAA+RLF+VIDSAPK+ID PDAVEI++P+GE+EFRDVWLTYHTGRTVL+GV+
Sbjct: 301 GDIQRSLAAAARLFEVIDSAPKAIDAPDAVEINDPKGEVEFRDVWLTYHTGRTVLRGVNL 360
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
KV PGEKVLI GPPGSGKSSILKLIARFY P KGEVLIDGVNV KIKTE+LR+IVAYVPQ
Sbjct: 361 KVSPGEKVLIVGPPGSGKSSILKLIARFYVPDKGEVLIDGVNVKKIKTESLRRIVAYVPQ 420
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
EPFIFNRSIRENIALAKP+A +E+ RAAKIAKIHDFI+SLP GYDT+VGEKG+TLSGGQ
Sbjct: 421 EPFIFNRSIRENIALAKPDAKMDEIIRAAKIAKIHDFISSLPNGYDTIVGEKGVTLSGGQ 480
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
RQRIALARA+L++PKI+LLDDPVSNLDAETEK+LVEDLKEIL+ +TALIVSQRLSLVKL
Sbjct: 481 RQRIALARALLLDPKIILLDDPVSNLDAETEKRLVEDLKEILKGRTALIVSQRLSLVKLT 540
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGG 575
DRVIV+KDG+I+E+GKP EL+KKGG FSEM++A G
Sbjct: 541 DRVIVIKDGRIIEEGKPSELVKKGGAFSEMIRAIG 575
>sp|Q9WYC4|Y288_THEMA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN TM0288
>gi|7445855|pir||F72396 ABC transporter, ATP-binding
protein - Thermotoga maritima (strain MSB8)
>gi|4980786|gb|AAD35376.1|AE001710_11 (AE001710) ABC
transporter, ATP-binding protein [Thermotoga maritima]
Length = 598
Score = 359 bits (912), Expect = 4e-98
Identities = 195/564 (34%), Positives = 322/564 (56%), Gaps = 3/564 (0%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
L RLL YLR H ++ + + S + P LI ID + + RY L++
Sbjct: 25 LRRLLGYLRPHTFTLIMVFVFVTVSSILGVLSPYLIGKTIDVVFVPRRFDLLPRYMLILG 84
Query: 68 LVGVLNGV-FSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITND 126
+ L + F L G+ +L +Q V+ LR + F +QR + FFD+T G +ISR+ ND
Sbjct: 85 TIYALTSLLFWLQGKIMLT-LSQDVVFRLRKELFEKLQRVPVGFFDRTPHGDIISRVIND 143
Query: 127 TERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRP 186
+ I L + I + ++ M R+N+ L++V L + + V + + + R
Sbjct: 144 VDNINNVLGNSIIQFFSGIVTLAGAVIMMFRVNVILSLVTLSIVPLTVLITQIVSSQTRK 203
Query: 187 IYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALY 246
+ + + G + I I+G+ IK + EE KF + NE L + KA + +
Sbjct: 204 YFYENQRVLGQLNGIIEEDISGLTVIKLFTREEKEMEKFDRVNESLRKVGTKAQIFSGVL 263
Query: 247 GNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRS 306
+V L + + +GG +++ +TVG + F+ Y PL L IQ +
Sbjct: 264 PPLMNMVNNLGFALISGFGGWLALKDIITVGTIATFIGYSRQFTRPLNELSNQFNMIQMA 323
Query: 307 LAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGE 366
LA+A R+F+++D + D PDAVE+ RGEIEF++VW +Y + VLK ++F +KPG+
Sbjct: 324 LASAERIFEILDLEEEK-DDPDAVELREVRGEIEFKNVWFSYDKKKPVLKDITFHIKPGQ 382
Query: 367 KVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFN 426
KV + GP GSGK++I+ L+ RFY +G++L+DG+++ KIK +LR + V Q+ +F+
Sbjct: 383 KVALVGPTGSGKTTIVNLLMRFYDVDRGQILVDGIDIRKIKRSSLRSSIGIVLQDTILFS 442
Query: 427 RSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIAL 486
+++EN+ P AT EE++ AAK+ FI LP+GY+TV+ + G LS GQRQ +A+
Sbjct: 443 TTVKENLKYGNPGATDEEIKEAAKLTHSDHFIKHLPEGYETVLTDNGEDLSQGQRQLLAI 502
Query: 487 ARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVM 546
RA L NPKI++LD+ SN+D +TEK + + ++++ KT++I++ RL+ +K D +IV+
Sbjct: 503 TRAFLANPKILILDEATSNVDTKTEKSIQAAMWKLMEGKTSIIIAHRLNTIKNADLIIVL 562
Query: 547 KDGKIVEDGKPEELIKKGGIFSEM 570
+DG+IVE GK +ELI+K G + E+
Sbjct: 563 RDGEIVEMGKHDELIQKRGFYYEL 586
>dbj|BAA96814.1| (AB040146) ABC transporter B [Thermus thermophilus]
Length = 600
Score = 353 bits (896), Expect = 3e-96
Identities = 193/578 (33%), Positives = 344/578 (59%), Gaps = 15/578 (2%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKG-VSTGAYKVAIRYGLLI-- 66
R+L Y+ + + ++ L +++++ + P+ + AID V T +A R+ LL+
Sbjct: 17 RILRYVWPYRLQVVLALLFLLVVTLAAAATPLFFKWAIDLALVPTEPRPLAERFHLLLWI 76
Query: 67 ----LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISR 122
L V ++ + YL+ Q ++ LR D F + R F+D+ G+L++R
Sbjct: 77 SLGFLAVRAVHFAATYGETYLIQWVGQRVLFDLRSDLFAKLMRLHPGFYDRNPVGRLMTR 136
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
+T+D + I +F++ + ++ +F ++ L +M+ ++ LT+V L+ +++ + T +
Sbjct: 137 VTSDVDAINQFITGGLVGVIADLFTLVGLLGFMLFLSPKLTLVVLLVAPVLLAVTTWVRL 196
Query: 183 KVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKI 242
+R Y ++R + + + ++G++TI+ E + KF + N +L+ V+ ++
Sbjct: 197 GMRSAYREMRLRLARVNAALQENLSGVETIQLFVKEREREEKFDRLNRDLFRAWVEIIRW 256
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
AL+ + A++++ YYGG +++ +++G LVAF+ Y + PL+ L
Sbjct: 257 FALFFPVVGFLGDFAVASLVYYGGGEVVRGAVSLGLLVAFVDYTRQLFQPLQDLSDKFNL 316
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-------VL 355
Q ++A+A R+F V+D+ + DP D I + RGE+EFRDVWL Y VL
Sbjct: 317 FQGAMASAERIFGVLDTEEELKDPEDPTPIRSFRGEVEFRDVWLAYTPKGVEPTEKDWVL 376
Query: 356 KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIV 415
KGVSF+V+PGEKV + G G+GK+S++ LIARFY P +G V +DGV+V + + E LR+ V
Sbjct: 377 KGVSFRVRPGEKVALVGATGAGKTSVVSLIARFYDPQRGCVFLDGVDVRRYRQEELRRHV 436
Query: 416 AYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
V QEPF+F+ ++ +N+ L P+ E VE ++ H+FI LPKGY TV+GE+G
Sbjct: 437 GIVLQEPFLFSGTVLDNLRLFDPSVPPERVEEVSRFLGAHEFILRLPKGYQTVLGERGAG 496
Query: 476 LSGGQRQRIALARAMLMNPKIVL-LDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRL 534
LS G++Q +AL RA+L +P I+L LD+ +++D+ETEK+L E L + ++ +T+LI++ RL
Sbjct: 497 LSTGEKQLLALVRALLASPDILLILDEATASVDSETEKRLQEALYKAMEGRTSLIIAHRL 556
Query: 535 SLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
S ++ VDR++V + G++VE+G EEL+ KGG ++ + +
Sbjct: 557 STIRHVDRILVFRKGRLVEEGSHEELLAKGGYYAALYR 594
>pir||F75142 abc transporter ATP-binding protein PAB2148 - Pyrococcus abyssi
(strain Orsay) >gi|5457731|emb|CAB49221.1| (AJ248284)
ABC TRANSPORTER ATP-BINDING PROTEIN [Pyrococcus abyssi]
Length = 580
Score = 337 bits (856), Expect = 2e-91
Identities = 189/569 (33%), Positives = 320/569 (56%), Gaps = 2/569 (0%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
+ S++ L R + I + I+ + N P ++R AID + G YK
Sbjct: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
+L LL V F+ + Q + LR I + ++FF +G L+S
Sbjct: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
RI NDT + L + L SI + + M+ +++ LT+V L ++ ++V + +
Sbjct: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
K+R Y + R + I+S+ ++AGI+TI++ E++V+ +FS+ + E ++
Sbjct: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
++ + L++ + YGG + +++G +VAF+ Y P+ +
Sbjct: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
Query: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFK 361
+Q +LAA R+++++D ++++ + + + +GEIEFR+VW Y GR VLK V+
Sbjct: 304 SLQSALAALERIYEILDD--ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLY 361
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
+ P KV I G G+GK++I LI RFY PTKGE+L DG++ KI ++LRK + YVPQE
Sbjct: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
Query: 422 PFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQR 481
++F +I ENI +A P A +E+V R K IHDFI LPKGY+T GE G LS G+R
Sbjct: 422 TYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
Query: 482 QRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVD 541
Q I+LARAML +P IV+LD+ +S++D +TE+ + + ++++ +T++I++ RLS+ + D
Sbjct: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFAD 541
Query: 542 RVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+VIV+ DG+IVE+G P EL+ + G F ++
Sbjct: 542 KVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
>pir||H69857 ABC transporter (ATP-binding protein) homolog yknU - Bacillus
subtilis >gi|2633803|emb|CAB13305.1| (Z99111) similar to
ABC transporter (ATP-binding protein) [Bacillus
subtilis] >gi|3282116|gb|AAC24906.1| (AF012285) YknU
[Bacillus subtilis]
Length = 585
Score = 335 bits (851), Expect = 6e-91
Identities = 191/562 (33%), Positives = 312/562 (54%), Gaps = 1/562 (0%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
RL Y + F+ L ++LM+ + P++++ ID+ V Y++A L + V
Sbjct: 6 RLKMYYWPYRKVFMWSLLAMLLMTAITVVYPIILQITIDEIVLGRQYQLAAWVSLGFIAV 65
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
VL G+ + +YL +VY LR + +QR ++D +G L+SR+T D E
Sbjct: 66 MVLKGMATFFHQYLGDMFGIKSVYRLRNGLYEKLQRLSFSYYDNAKTGDLMSRLTADVEG 125
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ FLS+ + L+ L+ ISL M ++ LT+V + + + + +V P +
Sbjct: 126 LRFFLSYGLAELIRFGLLVAISLSVMFYYSVPLTLVTIAVLPFLAVAVYRFDKRVHPAFR 185
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
IR + + I+GI T+KSLS E+ + F++ N E + ++ I + Y
Sbjct: 186 GIRKSFAKLNTKVQENISGINTVKSLSREDFQISTFNKANAEYRAQYLQTSSIWSAYFPL 245
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
+ + + YGG ++QN L GELVAF + + MMWP+ LGF I ++ A+
Sbjct: 246 MEFIGNTCIVALLSYGGYLVMQNQLNPGELVAFFSLVNYMMWPIMNLGFVINMFSQAKAS 305
Query: 310 ASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-VLKGVSFKVKPGEKV 368
RL D+++ D P A+ G++ F++V L Y +T L VSF+ G+ +
Sbjct: 306 GERLLDILEKEEDITDHPHALHKQKLTGDVHFKNVSLAYGKEQTNALCNVSFEANSGKVI 365
Query: 369 LITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRS 428
+ GP GSGKSS+ +L+ RFY P G + ID + + LR + V QE F+F+ +
Sbjct: 366 GLLGPTGSGKSSVTQLLTRFYSPVGGMITIDHKPITDYSLKTLRSNIGVVLQESFLFSST 425
Query: 429 IRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALAR 488
IR NI+ +P+A+ E+V AAK A+ H+FI LP GYDT++GE+G+ LSGGQ+QRIA+AR
Sbjct: 426 IRSNISYGRPDASMEDVIEAAKRAQAHNFIMELPDGYDTMLGERGMGLSGGQKQRIAIAR 485
Query: 489 AMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKD 548
A+ +NP I++LDD S +D +TE + LKE+++++T IV+ R+S +K D ++V
Sbjct: 486 AICLNPSILILDDATSAVDMQTEHSIQLALKEVMKNRTTFIVAHRISSLKHADEILVFNK 545
Query: 549 GKIVEDGKPEELIKKGGIFSEM 570
G+I E G EL++KGG + ++
Sbjct: 546 GRIRERGTHHELLEKGGYYKKI 567
>dbj|BAB10828.1| (AB016892) ABC transporter-like protein [Arabidopsis thaliana]
Length = 655
Score = 334 bits (848), Expect = 1e-90
Identities = 186/573 (32%), Positives = 325/573 (56%), Gaps = 11/573 (1%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPV---LIRNAIDKGVSTGAYK----VAIRYG 63
++S + A +IG +++ S TN +VP +I + + + V T + +A+R
Sbjct: 71 MVSQAKPDAGKLVIGTIALLIGSTTNLLVPKFGGMIIDIVSRDVKTPEQQTESLIAVRNA 130
Query: 64 LLILLVGVLNGVFSLAGR-YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISR 122
++I+L+ V+ G A R +L A++ V LR D FR + E+ F+D T +G+L+SR
Sbjct: 131 VVIILLIVVIGSICTALRAWLFNSASERVVARLRKDLFRHLMHQEIAFYDVTKTGELLSR 190
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
++ DT+ I + + L ++ +I + +M + LT++AL+ + ++ +
Sbjct: 191 LSEDTQIIKNAATTNLSEALRNVTTALIGVGFMFTSSWKLTLLALVVVPVISVAVKQFGR 250
Query: 183 KVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKI 242
+R + + V ASIA + ++T++S + E + +++S++ +E L +K +
Sbjct: 251 YLRELSHTTQAAAAVAASIAEESFGAVRTVRSFAKESYMVSQYSKKVDETLKLGLKQAVL 310
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
L+ L++ T+ YG I ++TVG L +F+ Y LT+ + +L
Sbjct: 311 VGLFFGGLNAAFTLSVITVVSYGAYLTIYGSMTVGALTSFILYSLTVGSSVSSLSSLYTT 370
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKGVSF 360
++ A+ R+F ++D D + NP G++E DVW Y + +LKG+S
Sbjct: 371 AMKAAGASRRVFQILDRVSSMSSSGDKCPVGNPDGDVELNDVWFAYPSRPSHMILKGISL 430
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
++ PG KV + GP G GK++I LI RFY P KG++L++GV++ +I + L K ++ V Q
Sbjct: 431 RLTPGSKVALVGPSGGGKTTIANLIERFYDPLKGKILLNGVSLMEISHQYLHKQISIVSQ 490
Query: 421 EPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP +FN S+ ENIA A+ ++E AAK+A H+FI + P Y+TVVGE+G+ LSGG
Sbjct: 491 EPILFNCSVEENIAYGFDGEASFTDIENAAKMANAHEFIEAFPDKYNTVVGERGLRLSGG 550
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKL 539
Q+QRIA+ARA+L NP ++LLD+ S LDAE+E + + + ++ +T L+++ RLS VK
Sbjct: 551 QKQRIAIARALLTNPSVLLLDEATSALDAESEYLVQDAMDSLMAGRTVLVIAHRLSTVKT 610
Query: 540 VDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
D V V+ DG++ E G +EL+ GI++ ++K
Sbjct: 611 ADCVAVISDGEVAEKGTHDELLSLNGIYTNLVK 643
>dbj|BAB04844.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 581
Score = 324 bits (823), Expect = 1e-87
Identities = 183/558 (32%), Positives = 307/558 (54%), Gaps = 5/558 (0%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
RL + + +F LF + +M+ + P++++ ID V G Y + L +++V
Sbjct: 6 RLAQFYWPYRRYFYWSLFAMGVMTLMTVLYPIILQFTIDNAVIGGRYDLIPWLALALIIV 65
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
GV +YL AVY LR + +Q ++D +G L+SR+T D E
Sbjct: 66 MGFKGVMVYIHQYLGDLFGVTAVYRLRNSLYEKLQYLPFRYYDNAKTGDLMSRLTGDVET 125
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
FLSF + I L+ S+ M+ ++ LT+ + T+ + + + +V P +
Sbjct: 126 FRFFLSFGFAQFIQFILLVSFSMGVMLYYSVPLTLATMCTLPFLAIVVAKFDRRVHPGFR 185
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
IR + + ++G+ T+K+LS E+ ++F N + ++ ++ Y
Sbjct: 186 DIRKSLAKLNTKVQENVSGMNTVKALSQEDEEVSRFEDRNVDYRQKHLDIARVWGNYFPL 245
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
+ L+ + +GG +I ++ G+LVAF + + ++ P+ LGF I +S A+
Sbjct: 246 MEFIGNLSAVFLLSFGGYLVITGSMQTGQLVAFFSLVWYIIGPIMNLGFIINTFSQSKAS 305
Query: 310 ASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-VLKGVSFKVKPGEKV 368
RL +++D + + D E ++ +G + FRDV L Y T L+ VSF+ G+ +
Sbjct: 306 GERLLEILDEENRVDEGKD--ERTSLQGSVTFRDVCLNYRGAETPALQNVSFEAPAGKTI 363
Query: 369 LITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRS 428
+ G GSGK+SI++L+ RFY+ T GE+LIDG + E LR + V QE F+F+ +
Sbjct: 364 GLVGATGSGKTSIVQLVNRFYERTSGEILIDGKPIESYPLETLRSQIGVVLQESFLFSST 423
Query: 429 IRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALAR 488
IR+NIA +P+ + +E+ AA+ A+ HDFIA LP GYDTV+GE+G+ LSGGQ+QRIA+AR
Sbjct: 424 IRDNIAYGRPDVSMKEIIAAARRAQAHDFIAELPDGYDTVLGERGLGLSGGQKQRIAIAR 483
Query: 489 AMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKD 548
A+LMNP I++LDD S +D +TE K+ +E+++ +T I++ R+S VK D ++V+
Sbjct: 484 AILMNPSILILDDATSAVDMKTEHKIQAAFREVMKGRTTFIIAHRISSVKQADEILVLDG 543
Query: 549 GKIVEDGKPEELI--KKG 564
GK+ E G L+ KKG
Sbjct: 544 GKVCERGTHHTLLQNKKG 561
>pir||S72637 hypothetical ABC exporter component A - Thermoanaerobacterium
thermosulfurigenes >gi|1542974|gb|AAB08041.1| (U50951)
AbcA [Thermoanaerobacterium thermosulfurigenes]
Length = 582
Score = 324 bits (821), Expect = 2e-87
Identities = 183/561 (32%), Positives = 314/561 (55%), Gaps = 1/561 (0%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
R+L Y+ + ++ ++ ++L + P L DK G + + +
Sbjct: 3 RVLKYVLRYKLYVIVPSIAMVLAIALDMFNPYLQEIITDKVFIGGDKSLLWPILWAFIAI 62
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
+ V Y+ + ++ D F IQ FFD +G+L+SRI D +
Sbjct: 63 TAVRTVLGYLREYIFDVLSAKISVDIKKDLFDHIQSLPFSFFDNMNTGELMSRIGEDVDN 122
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ R +SF +R+ + ++ I + + +N LT+V+L+ + I+ L + K+ Y
Sbjct: 123 VWRSVSFGIRLFIENMIYFITASTILFFINWKLTLVSLLGMPIIGYLALQFEKKIGISYG 182
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
K+ Q ++ + A IAG++ +K+ + E+ KF N E + L+++ +I A Y
Sbjct: 183 KLSDQGVLMNTAAQENIAGVRLVKAFAREKYEIMKFLSLNNENFELSMEQNRIVAKYFPP 242
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
+ ++ + +GG +I+++L++GELVAF Y+ ++WP+R LGF I +S A+
Sbjct: 243 IDFLTNFSIVILVVFGGMLVIKSSLSIGELVAFSGYIYMLIWPMRMLGFLTNLIAQSDAS 302
Query: 310 ASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVL 369
A ++ ++D P D D++ I +G++EF+ V+ YH VLK ++FKV G+ V
Sbjct: 303 AKKIMRIMDIVPSIKDSEDSIRIKELKGDVEFKHVFFKYHDDM-VLKDINFKVSAGQTVA 361
Query: 370 ITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSI 429
I G GSGKSS++ LI R+Y G V IDG +V + +LR +A V Q+ F+F+ SI
Sbjct: 362 IMGTTGSGKSSLVNLIGRYYDVFDGAVYIDGHDVRSLNLHDLRSQMAVVQQDTFLFSESI 421
Query: 430 RENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARA 489
EN+ K +A+ EEV+ A ++A DF+ YDT+VGE+GI LSGGQ+QRI++ARA
Sbjct: 422 EENVRFGKEDASFEEVKEALRLACADDFVEEFDDKYDTIVGERGIGLSGGQKQRISIARA 481
Query: 490 MLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDG 549
++ + KI++LDD S LD +TE +L+++L E ++ T I++ R+S VK D ++ M+DG
Sbjct: 482 LIRDAKILILDDATSALDMDTEFRLLKNLSERRKNATTFIIAHRISAVKNADMILYMEDG 541
Query: 550 KIVEDGKPEELIKKGGIFSEM 570
+IVE G +EL++K G + E+
Sbjct: 542 RIVERGTHDELLEKRGRYYEI 562
>dbj|BAB04845.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 601
Score = 317 bits (804), Expect = 2e-85
Identities = 187/572 (32%), Positives = 320/572 (55%), Gaps = 8/572 (1%)
Query: 7 QLIRLLSYLRGHAVHFLIGLFL-IILMSYTNSIVPVLIRN-AIDKGVSTGAYKVAIRYGL 64
Q++RLL+Y++ +A L + +++++ VP++I AID ++ G V +
Sbjct: 26 QMMRLLTYMKPYAASLLPKTVVAMLIVTAVRLFVPIIIGVLAIDHAIAAGDLNVMYQLAA 85
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
L+L + ++ V ++ + + Q+ +Y +R D F IQR FFD+ +G ++ R+
Sbjct: 86 LVLGLYSISYVANVFRIRWMNEIGQHVIYDIRADLFNHIQRLSHRFFDQRSAGSILVRVV 145
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
ND + + V LL I +++ + + ++ L ++ LI + I+ ++T +
Sbjct: 146 NDVNSLQDLFTNGVINLLMDIVILLGIIVILFSLSPELAILILIVLPIMFFISTKLRRNI 205
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
R + +R + + S +I GI+ ++ S E+ F NEE + A ++ A
Sbjct: 206 RRSWQTVRLRQSKLNSHLNESIQGIRVTQAFSQEKENMRFFRDINEENFQSWKDATRMNA 265
Query: 245 LYGNAPFLVLGLAMST--MFYYGGKAIIQNTLTVGELVAFLTYMLTMMW-PLRALGFTIG 301
L+ PF+ + A+ + +YG I LTVG V+F Y L M W P+ LG
Sbjct: 266 LF--RPFVEMASAIGAVVLIWYGVSLIQSEVLTVGVFVSFAFY-LGMFWEPISRLGQVYN 322
Query: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFK 361
+ +A++ R+F+ +D P + +AV + RG + F V +Y R L +SF+
Sbjct: 323 QLLVGMASSERIFEFLDEKPSVPEKENAVTLHEMRGHVTFEQVEFSYDDKRKALNDISFE 382
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
+K G+ + + G GSGKS+I+ LI+RFY PT G + IDGV++ I+ +LR V++V Q+
Sbjct: 383 IKAGQTIALVGHTGSGKSTIVNLISRFYDPTAGVIKIDGVDLRDIQLNSLRTNVSFVLQD 442
Query: 422 PFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQR 481
FIF +I ENI +P AT EEV+ AA+ +DFI LP GYDT V EKG LS G+R
Sbjct: 443 TFIFAGTIMENIRFGRPTATDEEVKAAAEAIGANDFIERLPNGYDTEVEEKGNVLSVGER 502
Query: 482 QRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVD 541
Q ++ ARA+L +PKI++LD+ +++D ETE K+ LK++L D+TA++++ RLS ++ D
Sbjct: 503 QLLSFARALLADPKILILDEATASIDTETELKIQAGLKKLLHDRTAIMIAHRLSTIRDAD 562
Query: 542 RVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
++IV++ G I+E G EL+ G + ++KA
Sbjct: 563 QIIVLEQGDIIEQGTHSELMDARGTYYGLVKA 594
>pir||B71182 probable ABC transporter ATP-binding protein - Pyrococcus
horikoshii >gi|3258166|dbj|BAA30849.1| (AP000007) 582aa
long hypothetical ABC transporter ATP-binding protein
[Pyrococcus horikoshii]
Length = 582
Score = 317 bits (804), Expect = 2e-85
Identities = 179/564 (31%), Positives = 310/564 (54%), Gaps = 2/564 (0%)
Query: 4 SINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYG 63
S + LIR + ++ + I+ + N P ++ AID + G Y
Sbjct: 10 SFSLLIRFIREALSEKKTLVVVIISIVGSAIANLASPYVLHIAIDNYIVPGKYGELWFVT 69
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
LL LL + F Y Q + LR I ++FF + +G L+SRI
Sbjct: 70 LLYLLSLIGQWFFMTLQTYYTEVFGQGVLKRLRSKLHEKILISNLDFFKEKSTGDLVSRI 129
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
NDT + L + L S+ + + M +++ LT+V L ++ ++V + + K
Sbjct: 130 INDTNIVNDVLVSGLLGGLGSLLSLAGIIIAMFLLDVKLTLVTLASVPLMVLVAYYFGGK 189
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
+R Y + R + I+S+ ++AGI+TI++ E +V+ +FS+ + E ++
Sbjct: 190 MRRAYRETRQKIAKISSVVEESVAGIETIRAFGKERDVEREFSKVSLETIKAYLRVAVYM 249
Query: 244 ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
++ + L++ + YGG + +++G +VAF+ Y P+ + +
Sbjct: 250 GVFWPLMNITSLLSVIAVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 309
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVK 363
Q +LAA R+++++D ++++ + + + GEIEFR+VW Y GR VLK ++ +
Sbjct: 310 QSALAALERIYEILDD--ENVEDYNGINVERLNGEIEFRNVWFEYERGRPVLKDINLLIP 367
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
G KV I G G+GK+++ LI RFY PTKG++ DG+ KI ++LR+ + YVPQE +
Sbjct: 368 SGSKVAIVGKTGAGKTTLANLIMRFYDPTKGDIFYDGIEGRKISRKSLRRRIGYVPQETY 427
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+F +I ENI +A P A +E+V R K IH+FI LP GY T GE G LS G+RQ
Sbjct: 428 LFPGTIMENILMANPEAREEDVIRVCKELGIHEFIMKLPNGYKTSAGEAGKLLSLGERQL 487
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
I+LARA+L +P IV+LD+ +S++D +TE+ + + ++++ +T++I++ RLS+ + D+V
Sbjct: 488 ISLARALLKDPDIVILDEALSSVDPKTEQLVQNAMLKLMEGRTSIIIAHRLSITRFADKV 547
Query: 544 IVMKDGKIVEDGKPEELIKKGGIF 567
IV+KDG+I+E+G P+ L++K G F
Sbjct: 548 IVVKDGRIIEEGPPKLLLEKKGYF 571
>sp|P54719|YFIC_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN 2 IN GLVBC
3'REGION >gi|7445745|pir||F69802 ABC transporter
(ATP-binding protein) homolog yfiC - Bacillus subtilis
>gi|1486245|dbj|BAA09107.1| (D50543) unknown [Bacillus
subtilis] >gi|2633146|emb|CAB12651.1| (Z99108) similar
to ABC transporter (ATP-binding protein) [Bacillus
subtilis]
Length = 604
Score = 314 bits (796), Expect = 2e-84
Identities = 169/566 (29%), Positives = 311/566 (54%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
L R+ SYL ++ + ++++ + + P +I AID + I LL+L
Sbjct: 35 LRRIWSYLAERKGLLILVMLMVVISAIFGLLGPFVIGKAIDHFIVGKTVSGLIPVLLLLL 94
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
+ ++ + Y ++ +Q V+ +R + F + + FFDK G+L+SR+TND
Sbjct: 95 AIYIIQSLSLWFQNYWMITISQGTVFRMRSELFTHLHELPIPFFDKQRHGELMSRVTNDI 154
Query: 128 ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
E ++ L+ V +L S+ + ++ M+ M+ LT++ L I ++ + +
Sbjct: 155 ENVSSTLNTSVIQILSSVITFVGTIAVMLYMSPLLTLITLTIIPVMAASLKWITNRTGKL 214
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYG 247
+ + + G + +++G K IK+ S E+ + +F ++N L + A I+
Sbjct: 215 FKEQQKNLGDLNGYIEESVSGAKVIKAYSREKQITAEFLEKNAALKTSGFWAQTISGFIP 274
Query: 248 NAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL 307
+ L+ + + GG ++ +++G +V F Y PL L + ++
Sbjct: 275 KVMNSLNNLSFTMIAAIGGLFALKGWISIGSIVVFAEYSRQFTRPLNDLANQFNTMLSAI 334
Query: 308 AAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEK 367
A A R+FDV+D + D +AV G IEFRDV Y G+ LK + F V G+
Sbjct: 335 AGAERVFDVLDEKEEREDEKNAVHQPIQTGSIEFRDVSFGYDKGQQTLKHLQFTVPAGQS 394
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
+ GP G+GK+++ L+ARFY+P G++LIDG ++ + +LRK + +V Q+ F+F
Sbjct: 395 IAFVGPTGAGKTTVTNLLARFYEPNDGKILIDGTDIKTLTRASLRKNMGFVLQDSFLFQG 454
Query: 428 SIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALA 487
+IRENI + +A+ +EVE AAK A H FI LPKGYDTV+ + G +S GQ+Q I++A
Sbjct: 455 TIRENIRYGRLDASDQEVEAAAKTANAHSFIERLPKGYDTVLTQNGSGISQGQKQLISIA 514
Query: 488 RAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMK 547
RA+L +P +++LD+ SN+D TE + E L +++ +T++I++ RL+ ++ D+++V+K
Sbjct: 515 RAVLADPVLLILDEATSNIDTVTEVNIQEALARLMEGRTSVIIAHRLNTIQRADQIVVLK 574
Query: 548 DGKIVEDGKPEELIKKGGIFSEMMKA 573
+G+++E G +ELI++ G +S++ ++
Sbjct: 575 NGEMIEKGSHDELIRQKGFYSDLYES 600
>pir||F75321 ABC transporter, ATP-binding protein, MDR family - Deinococcus
radiodurans (strain R1)
>gi|6459843|gb|AAF11601.1|AE002041_5 (AE002041) ABC
transporter, ATP-binding protein, MDR family
[Deinococcus radiodurans]
Length = 677
Score = 312 bits (790), Expect = 9e-84
Identities = 187/608 (30%), Positives = 327/608 (53%), Gaps = 40/608 (6%)
Query: 1 MRKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIR-------NAIDKGVST 53
+R S++ L YL+ H +LIG+ +++ + + IR +D +T
Sbjct: 48 VRFSLDSFRTLWPYLKMHQRQYLIGIVAVMISNAVVLLPAYFIRLTIDGLTRTLDNNPAT 107
Query: 54 GAYKV--AIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFF 111
V A Y L ++ +++G F L R ++V A++ Y +R D F +Q + ++
Sbjct: 108 PGITVTQAGYYALAMVASSLVSGSFMLLMRRMIVVASRQTEYEIRRDLFAHLQTLDKNYY 167
Query: 112 DKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIA 171
D+ +G L++R+T D + L F ++ I + S M ++ LT++ + I
Sbjct: 168 DRARTGDLMNRLTGDLSAVREMLGFGAWQIVNIISGFVTSFAVMFGLSWQLTLIVVAVIP 227
Query: 172 IVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEE 231
I+VGL A + + + Q +IA+ A +G + +K ++E+ ++ N E
Sbjct: 228 IIVGLLAYMARLINARHKAAQEQNSLIAAKAQENFSGARVVKGYAIEDREIEEYRAMNLE 287
Query: 232 LYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQN--TLTVGELVAFLTYMLTM 289
L N+ +K+ + L+LG+A + G+ I++ T TVG L FL Y+ +
Sbjct: 288 LLRRNIALIKVDGPLRSFSNLLLGIAFGLILLVAGRLILRPDATFTVGMLTQFLLYIERL 347
Query: 290 MWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVE--ISNPRGEIEFRDVWLT 347
WP+ +G+ G QR LA+ +RL ++ D+ P D P E + +G++ F +V L
Sbjct: 348 AWPMLMVGWITGVTQRGLASWNRLQELFDARPLVRDEPGRTEPQLWPTQGDLSFENVSLR 407
Query: 348 Y-HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
Y HT VL ++ + G + ITGP GSGK+ + +LI R PT+G + IDG ++ +
Sbjct: 408 YGHT--QVLDHINLHIPAGTFLGITGPTGSGKTVLGQLITRSMDPTEGVIRIDGHDLRTV 465
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALA--------------------KPNATQ---- 442
E+LR +A VPQEPF+F+ +I NI PN Q
Sbjct: 466 PLEHLRSAIAVVPQEPFLFSDTIANNIGFGLNNDELPPVPTRVSVVGLPLPPNIPQHPDP 525
Query: 443 EEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
E V AA++A + D + S P+GYDTV+GE+G+TLSGGQRQR A+ARA++ P I++LDD
Sbjct: 526 ERVREAARLAGLADDVESFPEGYDTVLGERGVTLSGGQRQRTAIARAIVREPMILILDDS 585
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK 562
+S +D ETE+++++ L+++ Q +T ++++ R+S ++ D+++V+++G+I E G +EL+
Sbjct: 586 LSAVDTETERRIIQGLRQVAQGRTVILIAHRISTLRHADQIVVLEEGRITEQGTHDELLA 645
Query: 563 KGGIFSEM 570
GG ++E+
Sbjct: 646 LGGHYAEL 653
>emb|CAB66302.1| (AL136519) ABC transporter protein, ATP-binding component.
[Streptomyces coelicolor A3(2)]
Length = 1243
Score = 310 bits (787), Expect = 2e-83
Identities = 180/547 (32%), Positives = 304/547 (54%), Gaps = 7/547 (1%)
Query: 37 SIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLR 96
+ VP++ + ID + +A+ GLLI V+ V + RY + A + LR
Sbjct: 37 AFVPLITKVIIDDVIGDKTRDMAVWAGLLIGAALVVY-VLTYIRRYYGGRLALDVQHDLR 95
Query: 97 MDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMV 156
D + I R + D+ +GQ++ R T+D + I L F + M + ++ L +ISL M
Sbjct: 96 TDMYGTITRLDGRRQDELSTGQVVGRATSDLQLIQGLL-FMLPMTIGNVLLFLISLVIMA 154
Query: 157 RMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLS 216
+++ LT+VAL + + ++ P + Q +A + G+++G++ +K
Sbjct: 155 WLSLPLTLVALAVAPALWFIARRSRTRLHPATWYAQAQAAAVAGVVDGSVSGVRVVKGFG 214
Query: 217 VEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTV 276
EE K + +L++ ++ +++ A Y A V L M GG ++ +T+
Sbjct: 215 QEEQETGKLREVGRKLFAGRLRTIRLNATYTPALQAVPALGQVAMLALGGWLAVRGHITL 274
Query: 277 GELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPR 336
G VAF TY+ ++ P+R L + Q++ A R+ ++ID+ P D + P
Sbjct: 275 GTFVAFSTYLAQLVGPVRMLAMVLTVGQQARAGTERVLELIDTEPAIEDGTKTLPADAP- 333
Query: 337 GEIEFRDVWLTYHTG----RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPT 392
+EF DV Y TG R VL G+SF+++ GE + + G GSGKS++ L+ RFY T
Sbjct: 334 ATVEFDDVAFGYDTGDGEPRPVLDGLSFEIRAGETLAVVGSSGSGKSTVSLLLPRFYDVT 393
Query: 393 KGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIA 452
+G VL+ G +V ++ ++LR V VP++ F+F+ ++R NIA +P+AT EEVE AA+ A
Sbjct: 394 RGAVLVGGHDVRELTLDSLRAAVGLVPEDSFLFSDTVRANIAYGRPDATDEEVEAAARAA 453
Query: 453 KIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEK 512
+ H FI LP GY T VGE G+TLSGGQRQR+ALARA+L +P++++LDD S +DA E
Sbjct: 454 QAHGFITELPDGYGTTVGEHGLTLSGGQRQRVALARAILTDPRLLVLDDATSAVDARVEH 513
Query: 513 KLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
++ E LK++++ +T L+++ R S + L DR+ V+ G++ + G EEL ++ ++ ++
Sbjct: 514 EIHEALKQVMRGRTTLLIAHRRSTLGLADRIAVLDRGRLADLGTHEELQERSALYRRLLT 573
Query: 573 AGGVYGG 579
GG
Sbjct: 574 DPDELGG 580
Score = 272 bits (689), Expect = 6e-72
Identities = 159/559 (28%), Positives = 291/559 (51%), Gaps = 2/559 (0%)
Query: 15 LRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNG 74
LRG LI L L+ + + ++PVLIRN ID GV+ A A+ L+ LV VL
Sbjct: 670 LRGFRAPLLISLALVAVDAGMGLLLPVLIRNGIDDGVTQAALG-AVWASSLLGLVAVLAQ 728
Query: 75 VFSLAGRYLLV-KAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRF 133
+ G + + + +Y LR+ F +QR ++++++ +G++++R+T D + ++ F
Sbjct: 729 WAAQTGEIRMTGRTGERILYSLRLKIFAQLQRLGLDYYERELTGRIMTRMTTDVDALSTF 788
Query: 134 LSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRH 193
L + S+ + ++ +++ L ++ T+ ++ + Y+ R
Sbjct: 789 LQTGLVTAFVSVVTFFGIMVALLVIDVELALIVFATLPPLIIATYFFRKASVKAYELARE 848
Query: 194 QTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLV 253
+ + + ++AG++ +++ E + +F++ ++ ++ + ++Y L+
Sbjct: 849 RVSTVNADLQESVAGLRIVQAFRRERDGGRRFAERSDSYRQARIRGQWLISVYFPFVQLL 908
Query: 254 LGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRL 313
A + + GG I TLT G LVA+L Y+ P++ L Q++ + R+
Sbjct: 909 SSAAAAAVLVVGGARIDDATLTTGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRI 968
Query: 314 FDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGP 373
+++ + E++ RGEI F DV Y L G+ ++ G+ V G
Sbjct: 969 QELLREPTSTRAAEKPSEVTALRGEIAFEDVRFRYGDDEAALTGIDLRIPAGQTVAFVGE 1028
Query: 374 PGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENI 433
G+GKS+++KL+ARFY PT G V +DG ++ + + R + VPQE ++F ++R+ I
Sbjct: 1029 TGAGKSTLVKLVARFYDPTDGRVTVDGRDLRDLDLTSYRHRLGVVPQEAYLFPGTVRDAI 1088
Query: 434 ALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMN 493
A +P+AT +VE AA+ H+ IA+L GY V E+G LS GQRQ IALARA L++
Sbjct: 1089 AYGRPDATDAQVEAAARAVGAHEMIATLTGGYLHEVAERGRNLSAGQRQLIALARAELVD 1148
Query: 494 PKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVE 553
P ++LLD+ + LD TE ++ + I +T L+V+ RL+ DRV+VM G++ E
Sbjct: 1149 PDVLLLDEATAALDLATEAQVNQATDRIAGRRTTLVVAHRLTTAARADRVVVMDGGRVAE 1208
Query: 554 DGKPEELIKKGGIFSEMMK 572
DG +EL+ G ++ + +
Sbjct: 1209 DGTHDELLALDGRYARLWR 1227
>pir||A69858 ABC transporter (ATP-binding protein) homolog yknV - Bacillus
subtilis >gi|2633804|emb|CAB13306.1| (Z99111) similar to
ABC transporter (ATP-binding protein) [Bacillus
subtilis] >gi|3282117|gb|AAC24907.1| (AF012285) YknV
[Bacillus subtilis]
Length = 604
Score = 309 bits (784), Expect = 4e-83
Identities = 180/575 (31%), Positives = 316/575 (54%), Gaps = 14/575 (2%)
Query: 7 QLIRLLSYLRGHAVHFLIGLFLIILM-SYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
Q+ RLLSY++ + L FL +L+ + ++P+LI + TG LL
Sbjct: 29 QMWRLLSYVKPYRKTILPLSFLTVLIGTAVKLVIPILIGVYVLDQAITGRNSE-----LL 83
Query: 66 ILLVGVLNGVFSL--AGRYLLVK----AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
I L+ +++G++ L A L ++ Q+ +Y LR F +QR FFD+ +G +
Sbjct: 84 IQLIFIISGLYVLNYAANVLRIRWMNQLGQHVIYDLRQHLFTHVQRLSHRFFDQRSAGSI 143
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+ RI ND + + V LL + L+ + + ++ LT+ ++T+ I+ ++T+
Sbjct: 144 LVRIMNDINSLQELFTSGVINLLTDLLLLAGVIIILFTLSPELTIAIMVTLPIMFFISTS 203
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
K+R + +R + + S +I GI+ ++ + EE F N+E Y +A
Sbjct: 204 LRKKIRRSWQTVRLKQSKLNSHLNESIQGIRVTQAFTQEEENMAYFDGVNQENYESWREA 263
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMW-PLRALGF 298
+ A++ + + + + +YG I+ T+T+G V+F Y L M W P+ LG
Sbjct: 264 TRKNAMFRPLVEMTNAIGTAVLIWYGATLIMNETITIGVFVSFAFY-LGMFWEPISRLGQ 322
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGV 358
+ +A++ R+F+ +D P + P+A+ GEI F +V +Y R L V
Sbjct: 323 VYNQLLMGMASSERIFEFLDEQPNVKEKPNAIHNEKINGEISFEEVEFSYDEKRKALHAV 382
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
SF + G + + G GSGK++I LI+RFY G + IDG+ + + +LR ++ V
Sbjct: 383 SFSIPAGSTLALVGHTGSGKTTIANLISRFYDAAGGTIKIDGIPIKDLSLASLRSQISIV 442
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
Q+ FIF+ +I ENI +PNA+ EEV +A++ +FI+ L +GY T V E+G LS
Sbjct: 443 LQDTFIFSGTIMENIRFGRPNASDEEVMKASQAVGADEFISDLAEGYATEVEERGSVLSA 502
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
GQRQ I+ ARA+L +P I++LD+ +++D ETE K+ + LK +L+ +TA++++ RLS ++
Sbjct: 503 GQRQLISFARALLADPAIIILDEATASIDTETEVKIQQALKTLLKGRTAVMIAHRLSTIR 562
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
DR+IV+ G+ +E+G ++L+ KGGI++ ++KA
Sbjct: 563 DADRIIVLDHGRKIEEGNHDQLLAKGGIYAGLVKA 597
>pir||S72638 hypothetical ABC exporter component B - Thermoanaerobacterium
thermosulfurigenes >gi|1542975|gb|AAB08042.1| (U50951)
AbcB [Thermoanaerobacterium thermosulfurigenes]
Length = 594
Score = 306 bits (775), Expect = 5e-82
Identities = 172/567 (30%), Positives = 312/567 (54%), Gaps = 9/567 (1%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
L RL SYL + + + + +I + + PVL++ AIDK + G G+L++
Sbjct: 21 LKRLFSYLGKYKLKVFVVIMFLIFEMAVSLVNPVLMKTAIDKNIRNGDINGLFVIGILMV 80
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYA---VYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
LN + +A R +VK A + +R + + IQ+ FFD G++++R+
Sbjct: 81 S---LNFLSMMASRTRIVKMASVTNDILLNIRHELYSHIQKLSFSFFDSRPVGKILARVI 137
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIA-IVVGLNTTYAMK 183
D + + V + I +I M +N L + ++I + +V+GL + +
Sbjct: 138 GDVNSLQDLFNNSVTNFIPQILTVICVGTMMFYLNSKLALASMILLPMLVIGLFSIETLS 197
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
R + + R + + +GIK ++ + E+ + F + +++ +KA+++
Sbjct: 198 RRR-WQEFRRKRSTFNAYTHEDFSGIKVVQEFANEDKTSSVFFKLVKDMMDSFIKAVRLN 256
Query: 244 ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
L+ G+ ++Y+ K + +T+G ++AF Y+ P+ + +
Sbjct: 257 DLFWPMVDASYGIGAVILYYFSAK-FMGYGVTIGTIIAFTMYIGMFWRPILDISNFYNSL 315
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVK 363
S A+A R+F+++D P +D +A+++ +G +EF++V Y G VL VSFKV
Sbjct: 316 VMSFASAERIFEIMDIEPDIVDMKNAIKMPKIKGNVEFKNVTFGYEDGSVVLDDVSFKVN 375
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
GE + + GP G+GK++I+ LI+RFY P+KG VLIDG ++ ++ E+LR + + Q+ F
Sbjct: 376 AGETIALVGPTGAGKTTIVNLISRFYDPSKGAVLIDGKDIKHVELESLRSQMGIMLQDTF 435
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+F+ +I+ENI K +AT EE+ AAK H+FI + KGYDT V E+G LS GQRQ
Sbjct: 436 LFSATIKENIRYGKLDATDEEIIAAAKAVNAHEFIMKMEKGYDTEVNERGSRLSVGQRQL 495
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
I+ ARA+L NP+I++LD+ SN+D +TE+ + + ++ +L +T+ +++ RLS ++ DR+
Sbjct: 496 ISFARALLANPRILILDEATSNIDTQTERLVQKGIQRLLSGRTSFVIAHRLSTIRDADRI 555
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEM 570
+V+ GKIVE G +EL+ G++ ++
Sbjct: 556 MVIDGGKIVETGTHDELMNLRGLYYDL 582
>pir||A75590 ABC transporter, ATP-binding protein - Deinococcus radiodurans
(strain R1) >gi|6460730|gb|AAF12435.1|AE001863_60
(AE001863) ABC transporter, ATP-binding protein
[Deinococcus radiodurans]
Length = 602
Score = 305 bits (774), Expect = 7e-82
Identities = 182/568 (32%), Positives = 303/568 (53%), Gaps = 6/568 (1%)
Query: 7 QLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKG-VSTGAYKVAIRYGLL 65
QL RLL+Y R + + F++G+ ++ S + P L ID + G+ +
Sbjct: 24 QLRRLLAYARPYRLPFVLGVLATLISSGLGLVFPRLFGTLIDASFLKVGSTDTGPLDRTV 83
Query: 66 ILLVGV--LNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
+ L+G+ L+ F A YLL + V LR F + FF +G L SR+
Sbjct: 84 LSLLGIFALSACFGAAQAYLLARVGAGVVADLRRALFSHLLSLSPRFFGNHRTGDLTSRL 143
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
T+D + S + L F +I S+ +V+ + L+++ L I +V+G T +
Sbjct: 144 TSDVGTVQAVTSTALAQLASQGFTLIGSVLLLVQTSPRLSLLTLAIIPLVIGTAVTIGRR 203
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
+R + +++ A I+G++ ++S + E + ++ Q + ++ ++
Sbjct: 204 IRRVSREVQDAVAAANGQAEEAISGVRVVQSFTAEGLEEERYGQGVLASFRAALRRARLQ 263
Query: 244 ALY-GNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
AL G FL G A++ + ++GG+ ++ LT G LV FL Y L + + AL
Sbjct: 264 ALMTGVMSFLTFG-ALALVLWFGGRQVMSGALTPGNLVTFLFYALQVGGTVAALTGVFNQ 322
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKV 362
Q +L A+SR+F+++D P +S G + F DV TY G L+ ++F V
Sbjct: 323 FQEALGASSRIFELLDERSDLPGPAAPRPLSRAEGRVRFVDVGFTY-AGAPALQDITFDV 381
Query: 363 KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEP 422
G+ V + GP G+GK++++ LI RF+ T G V +DG +V +LR+ V VPQE
Sbjct: 382 PAGQVVALVGPSGAGKTTLVNLIPRFWDVTAGRVEVDGHDVRAYALADLRRQVGLVPQET 441
Query: 423 FIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQ 482
+F+ ++ ENI +P A+Q EVE AA A H+FI L GY VVGE+G+ LSGGQRQ
Sbjct: 442 LLFSGTVAENILYGRPGASQAEVEAAAHAAHAHEFICELEGGYGAVVGERGVKLSGGQRQ 501
Query: 483 RIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDR 542
R+A+ARA+L +P+I++LD+ S LD E+E + L+ ++ +T +V+ RLS ++ DR
Sbjct: 502 RVAIARAILKDPRILILDEATSALDNESEALVQAALERLMVGRTTFVVAHRLSTIRSADR 561
Query: 543 VIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++VM G++V DG E L+ GG++ E+
Sbjct: 562 ILVMDAGRVVADGTHEGLMAAGGLYREL 589
>dbj|BAA96813.1| (AB040146) ABC transporter A [Thermus thermophilus]
Length = 578
Score = 305 bits (774), Expect = 7e-82
Identities = 186/573 (32%), Positives = 306/573 (52%), Gaps = 11/573 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
R + L RL Y+ + +L + + + + P +R A+D + + V
Sbjct: 4 RSAAPLLRRLWPYVGRYRWRYLWAVLAGLASIFFFVLTPYFLRLAVDAVQAGRGFGV--- 60
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
Y L I+ L+G+ S A R L V A++ Y LR D + + +F+ K G L++
Sbjct: 61 YALAIVASAALSGLLSYAMRRLAVVASRQVEYDLRRDLLHHLLTLDRDFYHKHRVGDLMN 120
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+ D + + + M FL++++ M +N L A I+ G+
Sbjct: 121 RLNTDLSAVREMVGPGILMGSRLSFLVLLAFLSMYAVNARL---AFYLTLILPGIFLAMR 177
Query: 182 MKVRPIYDKIRHQTGV---IASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+R I + R V I+++A +GI+ +K ++E + F N ++
Sbjct: 178 FLLRLIDRRYREAQEVFDRISTLAQEAFSGIRVVKGYALERRMVAWFQDLNRLYVEKSLA 237
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
++ ++G A T+ + GG +++ L+VGELV F Y+ + WP+ LG+
Sbjct: 238 LARVEGPLHALLGFLMGFAFLTVLWAGGAMVVRGELSVGELVQFNAYLAQLTWPILGLGW 297
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDP-PDAVEISNPRGEIEFRDVWLTYHTGRTVLKG 357
+ QR L + RLF+++D P D P + + + GE+ F V L GR +L+G
Sbjct: 298 VMALYQRGLTSLRRLFELLDEKPAIRDEDPLPLALEDLSGEVRFEGVGLK-RDGRWLLRG 356
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
++ + G + ITG GSGKS + L+ R P++G V + G +I LRK V
Sbjct: 357 LTLTIPEGMTLGITGRTGSGKSLLAALVPRLLDPSEGRVYVGGHEARRIPLAVLRKAVGV 416
Query: 418 VPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLS 477
PQEPF+F+ +I ENIA +E VE AA++A IH+ I + PKGY+TV+GE+GITLS
Sbjct: 417 APQEPFLFSETILENIAFGLDEVDRERVEWAARLAGIHEEILAFPKGYETVLGERGITLS 476
Query: 478 GGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLV 537
GGQRQR+ALARA+ PKI++LDD +S +DAETE ++++ LK +L +T L++S R + +
Sbjct: 477 GGQRQRVALARALAKRPKILILDDALSAVDAETEARILQGLKTVLGKQTTLLISHRTAAL 536
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+ D +IV+ +G+IVE+G E L++ GG+++EM
Sbjct: 537 RHADWIIVLDEGRIVEEGTHESLLQAGGLYAEM 569
>pir||E72396 ABC transporter, ATP-binding protein - Thermotoga maritima (strain
MSB8) >gi|4980785|gb|AAD35375.1|AE001710_10 (AE001710)
ABC transporter, ATP-binding protein [Thermotoga
maritima]
Length = 577
Score = 305 bits (774), Expect = 7e-82
Identities = 159/553 (28%), Positives = 305/553 (54%), Gaps = 1/553 (0%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVG 70
L YL+ + + ++ +++ + P L+ +D+G++ G + + ++ G+L+L+V
Sbjct: 4 LARYLKPYWIFAVLAPLFMVVEVICDLSQPTLLARIVDEGIARGDFSLVLKTGILMLIVA 63
Query: 71 VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERI 130
++ V + A+Q LR D FR + + ++ + LI+R+TND ++
Sbjct: 64 LIGAVGGIGCTVFASYASQNFGADLRRDLFRKVLSFSISNVNRFHTSSLITRLTNDVTQL 123
Query: 131 TRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDK 190
+ +R+++ + L + + V +N+ L+ V + I +V L K P++ K
Sbjct: 124 QNLVMMLLRIVVRAPLLFVGGIVMAVSINVKLSSVLIFLIPPIVLLFVWLTKKGNPLFRK 183
Query: 191 IRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAP 250
I+ T + + + G++ +++ EE F + NE L + A +
Sbjct: 184 IQESTDEVNRVVRENLLGVRVVRAFRREEYENENFRKANESLRRSIISAFSLIVFALPLF 243
Query: 251 FLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAA 310
++ + M + ++GG + N + +G ++A+ Y++ +M+ L +G + I R+ A+A
Sbjct: 244 IFIVNMGMIAVLWFGGVLVRNNQMEIGSIMAYTNYLMQIMFSLMMIGNILNFIVRASASA 303
Query: 311 SRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-VLKGVSFKVKPGEKVL 369
R+ +V++ P + +A+ + N G + F +V Y VL GV+F VKPG V
Sbjct: 304 KRVLEVLNEKPAIEEADNALALPNVEGSVSFENVEFRYFENTDPVLSGVNFSVKPGSLVA 363
Query: 370 ITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSI 429
+ G GSGKS+++ LI R P +G V +D ++V +K ++LR ++ VPQE +F+ +I
Sbjct: 364 VLGETGSGKSTLMNLIPRLIDPERGRVEVDELDVRTVKLKDLRGHISAVPQETVLFSGTI 423
Query: 430 RENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARA 489
+EN+ + +AT +E+ AAKIA+IHDFI SLP+GYD+ V G SGGQ+QR+++ARA
Sbjct: 424 KENLKWGREDATDDEIVEAAKIAQIHDFIISLPEGYDSRVERGGRNFSGGQKQRLSIARA 483
Query: 490 MLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDG 549
++ PK+++LDD S++D TEK++++ LK + T I++Q++ L D+++V+ +G
Sbjct: 484 LVKKPKVLILDDCTSSVDPITEKRILDGLKRYTKGCTTFIITQKIPTALLADKILVLHEG 543
Query: 550 KIVEDGKPEELIK 562
K+ G +EL++
Sbjct: 544 KVAGFGTHKELLE 556
>gb|AAK43114.1| ABC transporter, ATP binding protein [Sulfolobus solfataricus]
Length = 863
Score = 304 bits (771), Expect = 1e-81
Identities = 169/552 (30%), Positives = 304/552 (54%), Gaps = 3/552 (0%)
Query: 23 LIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAG-- 80
++G L ++ + N + P L++ ID + + ++ + ++I L+ + + L+
Sbjct: 135 IVGATLSLITTGLNLVPPYLLKILIDSVLLSPSHPSTLFINIIIYLIVSYSALALLSSIQ 194
Query: 81 RYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRM 140
+L + LR ++ H+ F ++ +++SR+T D L + +
Sbjct: 195 NRILNNLGSRIINDLREILYKHAINHDYSFIERISPSRILSRLTTDAGNTNWLLVWGLPT 254
Query: 141 LLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIAS 200
L+ ++F II + +N TL LI + ++ L +Y K +Y + ++ I S
Sbjct: 255 LVTNLFTIIGIGVILFTLNPTLAAFILIPVPAIIYLIISYRRKSHRLYHRNWRRSADITS 314
Query: 201 IATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMST 260
TI ++S S EE + + +LY +V K+ ++Y ++ L+
Sbjct: 315 RINDTIPNFLVVRSFSKEEYESKRLREMLNKLYESSVAINKMNSVYWPLMGFIVNLSTVL 374
Query: 261 MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSA 320
+++ GG +I + +G + AF+ Y+ P+ L + IQ+SL +A R+ +V+++
Sbjct: 375 IWWVGGHEVISGIIEIGVITAFIAYVSQFYGPINNLSNVLPFIQQSLTSAERIREVLEAK 434
Query: 321 PKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSS 380
P+ +P + + P EI F V+ Y V+K ++ +KPGEKV I G GSGKS+
Sbjct: 435 PQITNPENPKRPNMP-AEIRFEHVYFGYDPHFPVIKDINIGIKPGEKVAIVGKSGSGKST 493
Query: 381 ILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNA 440
I KL+ RFY +G +LIDG+++ +I LR+ VAYVPQ+ +F+ ++ N+A N
Sbjct: 494 IAKLLLRFYDVNEGRILIDGIDIREIDLNYLRRKVAYVPQDVVLFDTTVGYNVAYGTDNV 553
Query: 441 TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLD 500
++ ++ RA KIAKIHD I LP YDT++GE+G LSGGQRQR+++ARA++ NP +++ D
Sbjct: 554 SEIDIIRACKIAKIHDEIVKLPFAYDTILGERGTYLSGGQRQRLSIARAIIKNPDVLIFD 613
Query: 501 DPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEEL 560
+ SNLD +E+++ E + ++ + KT ++++ + V D+VIV+ +GK+VE+GKP EL
Sbjct: 614 EATSNLDVTSEREVYETMIDVSKGKTVIMITHNVHEVMNSDKVIVLSNGKVVEEGKPIEL 673
Query: 561 IKKGGIFSEMMK 572
+ K G F +M K
Sbjct: 674 LNKKGEFYKMFK 685
>gb|AAG15222.1|AF288462_2 (AF288462) AbcA [Chloroflexus aurantiacus]
Length = 594
Score = 303 bits (767), Expect = 4e-81
Identities = 173/577 (29%), Positives = 329/577 (56%), Gaps = 12/577 (2%)
Query: 4 SINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVA--IR 61
+++ L L YL + L+GL L + +++ P+++R A+D+ V+ G I
Sbjct: 10 AMHHLRLLFPYLHRYRRRLLLGLLAAALGASVSALAPLVLRLAVDR-VANGTIVPLELIW 68
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
+G ++ + +++G A R L+ + LR D F + E F+ + ++G L++
Sbjct: 69 FGGALIGLAIIDGGLKFAQRMLIAVTSYRIENDLRADLFDRLLSFEQMFYQQHYTGDLMA 128
Query: 122 RITNDTERITRFLSFRVRMLLYSI--FLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
R+TND + +FL + +I FL L ++V+ + L +V L+ +A +V +
Sbjct: 129 RLTNDLSAVRQFLGPGLNGAATAILTFLAAAVLMFLVQPVLALIVVLLLPLATIVFV--A 186
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
++R I+ +++ Q GV+++ A AGI+T+K+ + EE F+ +NE LN++
Sbjct: 187 IGGRMRQIFHRVQDQFGVLSTRAQENFAGIRTVKAFAQEEAEIAVFTADNERYRDLNLRY 246
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
+ ++ A L LGL + + GG+ + TLT+GELV F Y+ + +P+ LG+
Sbjct: 247 VLLSGALWPAMTLCLGLISALILLVGGQMVAAGTLTIGELVQFNAYLALLAFPMIILGWM 306
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLT--YHTGRTVLKG 357
+ Q++ A+ RL D++ P I P + GEIEFR V + + + +L+
Sbjct: 307 VNLFQQATASLERLSDILRRQPL-ITSPATPRLPAGEGEIEFRGVGVRAGHSDQQWLLRD 365
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPT--KGEVLIDGVNVAKIKTENLRKIV 415
+SF+V G + I G G+GK++++ L+ R P G+VL+DG+++ + LR+++
Sbjct: 366 LSFRVPAGTVLAIVGATGAGKTTLINLLGRVRDPDVMSGQVLVDGIDIRDLDLAALRRMI 425
Query: 416 AYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
YVPQE F+F+ +RENI + + +++++ + + LP G +T+VGE+G+T
Sbjct: 426 GYVPQESFLFSIPLRENIGFGVETVDPDRLNYVVEVSRLVNDLDQLPGGMETMVGERGVT 485
Query: 476 LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLS 535
LSGGQ+QR+A+ARA++ +P+I++LDD +S++D T +++ L+ + +T +I++QR++
Sbjct: 486 LSGGQKQRVAIARALMRDPRILVLDDALSSVDTHTAAQILAGLRTEMTGRTTIIIAQRIA 545
Query: 536 LVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
V+ D++IV+ +G+IVE G +EL+ + G ++ M +
Sbjct: 546 TVRDADQIIVLDEGQIVERGSHQELLARNGRYAAMYR 582
>emb|CAB05917.1| (Z83327) transport-associated protein [Salmo salar]
Length = 739
Score = 298 bits (754), Expect = 1e-79
Identities = 168/578 (29%), Positives = 320/578 (55%), Gaps = 15/578 (2%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
+K+ L +L+ Y++ + + F L L+++ S +P D ++ +
Sbjct: 138 KKTGASLEKLMGYMKPYIIRFGAVLSLVVISSLGEMAIPHYTGRMTDWIMNEDEPEAFTH 197
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
+++ L+ V++ V + ++ F+++ + E+ FFDK +G L+S
Sbjct: 198 AIMVMSLITVMSAVCEFVCDLIYNITMSRIHTSIQGLVFQSVLKQEIAFFDKAQTGDLVS 257
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
RIT DT ++ LS ++ +L++ + +M+ ++ L++ + + I+ +
Sbjct: 258 RITTDTNDMSESLSEKLSLLMWYFMRVTFLFLFMLNLSWKLSLFTAMGLPIIWVIPKISG 317
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ + K++ +AT T + +KT++S + EE ++ + E+ YSLN +
Sbjct: 318 KWHQELGAKVQKSLAQANDVATETFSSMKTVRSFANEEGETERYRKRLEKTYSLNKEE-- 375
Query: 242 ITALYGNAPFLVLGLAMSTMF------YYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
A Y + + +MS++F YYGG + T++ G+LVAF+ Y L + A
Sbjct: 376 -AAAYAASTWTN---SMSSLFLKVSILYYGGSLVTGGTVSSGDLVAFVLYELQFSSAVEA 431
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-- 353
+ + R++ + ++F+ +D P+ + P + N G ++F++V TY T
Sbjct: 432 VMSYYPSVMRAIGGSEKIFEYVDRQPQ-VPPEGTLAPQNLEGHVQFKNVTFTYPTREDTP 490
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VLKG+S +++PG+ + G G+GKS+ + L+ RFY P +GE+L+DG + K + L
Sbjct: 491 VLKGLSLELRPGQITALVGASGAGKSTCVSLLERFYLPQEGEILLDGEPLHSYKNQYLHD 550
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
++ V QEP +F RS+++NI + +AT EE+ RAA++A H FI+ LP GYDT GEKG
Sbjct: 551 KISVVSQEPVLFARSVKDNIKYGRDDATDEEIYRAAELANAHKFISDLPNGYDTDAGEKG 610
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+SGGQ+QRIA+ARA++ P+I++LDD SNLD E+E + + L + + L+++ +
Sbjct: 611 GQVSGGQKQRIAIARALIRKPRILVLDDATSNLDTESEHLVHQALLKDSNPCSVLLIAHK 670
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
LS V+ + ++V+++GK++E+G EL++KGG +++++
Sbjct: 671 LSTVEKANHIVVLEEGKVLEEGSHVELLEKGGTYADLV 708
>dbj|BAB04660.1| (AP001510) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 584
Score = 297 bits (753), Expect = 2e-79
Identities = 182/584 (31%), Positives = 301/584 (51%), Gaps = 22/584 (3%)
Query: 4 SINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYG 63
++ + R L ++R + I + + +L ++P+L+ ID + ++
Sbjct: 3 TLESIRRYLLFVRPYWKQIFITIIIGLLKFGIPLLIPLLVAYIIDGIIFAEQMTNEEKFS 62
Query: 64 LLILLVG-------VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
L ++G VL +Y +Y +R F IQ+ + F+
Sbjct: 63 ALFTVMGGIFFIFIVLRPPIEYYRQYFAQWIGNKILYDIRDHLFTHIQKLSLRFYSNRKV 122
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGL 176
G++ISR+ +D E+ F+ + + +F III+L M MN LT+VA+
Sbjct: 123 GEIISRVIHDVEQTKTFVMTGLMNIWLDMFTIIIALAIMFSMNAWLTLVAIAMFPF---- 178
Query: 177 NTTYAMKVRPIYDKIRHQTGVIASIATGT-------IAGIKTIKSLSVEENVQTKFSQEN 229
Y ++ Y K+RH T V + + G+ I+S ++E+ QT+F++ N
Sbjct: 179 ---YGFSIKYFYAKLRHLTRVRSQALADVQGHLHERVQGMSVIRSFALEDYEQTQFAKRN 235
Query: 230 EELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTM 289
+ + K A V +A + + +I L VG + AF+ YM +
Sbjct: 236 GTFLNRAIDHTKWNAKTFAVVNTVTDIAPLLVIFVAACFVINGELEVGAMTAFVLYMERL 295
Query: 290 MWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH 349
PLR L + + +S+A+ R+F+ ID +D AV++ G++ F V +Y
Sbjct: 296 YNPLRRLVNSSTTLTQSIASMDRVFEFIDEKYDIVDKEGAVKLEEVHGDVTFDHVSFSYE 355
Query: 350 TGRT-VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
T LK V F VK GE V G G GKS+++ LI RFY + G +LIDG ++ +
Sbjct: 356 KEETPALKDVHFHVKRGETVAFVGMSGGGKSTLISLIPRFYDVSSGRILIDGHDIRDYQV 415
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTV 468
+LR + V QE +F+ S+R NI + KP+AT+EEV AAK A HDFI +LP GYDT
Sbjct: 416 RSLRDQIGMVLQENILFSDSVRMNILMGKPDATEEEVIAAAKAANAHDFIMNLPNGYDTE 475
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
VGE+G+ LSGGQ+QR+A+AR L NP I++ D+ S LD E+E + E ++++ +++T
Sbjct: 476 VGERGVKLSGGQKQRVAIARVFLKNPPILIFDEATSALDLESEHYIQEAMEKLAKNRTTF 535
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
IV+ RLS + DR+IV+++G+IVE G +EL+ G++ ++ +
Sbjct: 536 IVAHRLSTITHADRIIVVENGEIVESGTHDELMSCNGVYKKLFE 579
>pir||C72275 ABC transporter, ATP-binding protein - Thermotoga maritima (strain
MSB8) >gi|4981820|gb|AAD36339.1|AE001781_10 (AE001781)
ABC transporter, ATP-binding protein [Thermotoga
maritima]
Length = 577
Score = 297 bits (752), Expect = 2e-79
Identities = 160/567 (28%), Positives = 319/567 (56%), Gaps = 8/567 (1%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVG 70
L+ +L+ + +L+G+ +I + +P +I +D ++T +L ++
Sbjct: 7 LVDFLKRNWHKYLLGVLSLIAVDLLQVYIPRVIGKIVDM-LNTETMNFDTLKIMLFWVMA 65
Query: 71 VLNGVF--SLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTE 128
+G+F R+ L A+ F + FFD+ SG+L++R TND
Sbjct: 66 AASGMFIGRFFWRFFLGGTARKFFLETSNKMFSKLLSLTPGFFDRMKSGELMARFTNDLS 125
Query: 129 RITRFLSFRVRMLLYSIFLIIISLYYMVRMNI--TLTMVALITIAIVVGLNTTYAMKVRP 186
+ R L + +L + F++I+ +++ + N+ L+ ++ + ++ ++ ++ +
Sbjct: 126 LLRRVLG-QGAILFFDSFIMIVMVFFFMIGNVGWKLSWISFAPLLLLAPVSMSFGRLIHR 184
Query: 187 IYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALY 246
+++ ++ TI+ ++ +KS SVE+ F + Y + A+K+++++
Sbjct: 185 KVSEVQRSFSELSGFTEETISSVRIVKSFSVEDVSFKIFENRALKNYEDTLSAIKVSSVF 244
Query: 247 GNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRS 306
L+ A YGG+A+I +++G+ +AF +Y+ ++WP+ A GF + QR
Sbjct: 245 RPLINLIASTAFFLALLYGGRAVINGKISLGDFIAFNSYLGMLVWPMMAYGFMVDLFQRG 304
Query: 307 LAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH-TGRTVLKGVSFKVKPG 365
AA RL + + P+ +P + I + E R++ Y T R VLK V+ K+ G
Sbjct: 305 RAAMRRLDTIFTAQPEVKEPEKPIRIDHFES-FEVRNLTYRYPGTEREVLKNVTMKINRG 363
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
E + I G GSGKS+I KL+ + Y +G++ I+GV++ + +EN+R IV VPQE F+F
Sbjct: 364 EMIGIAGSVGSGKSTIAKLLVKLYPVERGKIFINGVDINDVSSENIRSIVTLVPQETFLF 423
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
+ ++R NI + N ++++E K+A ++D I S P+ +DT+VGE+G+TLSGGQ+QRI
Sbjct: 424 SDTVRNNITVGLENVDEKKIEEVTKLAAVYDDIMSFPEKFDTIVGERGVTLSGGQKQRIT 483
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+ARA++ + ++ + DD +S +D ETE+++++ +++ ++ KT ++++ RL ++K DR+ V
Sbjct: 484 IARALIRDFEVYIFDDCLSAVDPETEERIIDSIRKGMKGKTIVVITHRLKVLKNADRIYV 543
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEMMK 572
+ +G+++E+G EEL+ + G++S M +
Sbjct: 544 LHEGRVIEEGTHEELMIRDGMYSRMYR 570
>pir||S75352 ABC-type transport protein slr2019 - Synechocystis sp. (strain PCC
6803) >gi|1652343|dbj|BAA17266.1| (D90904) ABC
transporter [Synechocystis sp.]
Length = 593
Score = 296 bits (751), Expect = 3e-79
Identities = 176/587 (29%), Positives = 327/587 (54%), Gaps = 19/587 (3%)
Query: 1 MRKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYK--- 57
M K I L+ LL+Y R H + +L + P LI A+D +
Sbjct: 1 MTKPIAPLLSLLNYSRVHRAKIYWAVTCSLLNKIFDLAPPALIGLAVDVVIKQQDSFLSR 60
Query: 58 ---VAIRYGLLILLVG-----VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEME 109
V+++ LL+L V L +F A L AQ + LR+DA+ +Q+ ++
Sbjct: 61 WGIVSVQSQLLVLTVASAVIWALESIFEYAYERLWRNLAQDIQHDLRLDAYAHLQQLDLA 120
Query: 110 FFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIII--SLYYMVRMNITLTMVAL 167
+F++ +G+L++ + +D ++ RFL +L + +++ ++++ +I +A+
Sbjct: 121 YFEERSTGRLMAILNDDINQLERFLDVGANEILQVLTTVVVIGGAFFVITPDIA--WMAV 178
Query: 168 ITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQ 227
+ + V+ + + + Y +R + + S + ++GI TIKS + E + Q
Sbjct: 179 VPMPFVLLGSIYFQSLLTSRYALVREKVSNLNSRLSNNLSGIMTIKSFATEAEEVERLRQ 238
Query: 228 ENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGE--LVAFLTY 285
+++ N +A+ ++A + +++ ST+ Y+GG ++ L VG ++ FLT
Sbjct: 239 DSDAYRDSNQRAIALSAAFVPLIRVIIFAGFSTILYFGGLDAVRGNLAVGSYSMLVFLTQ 298
Query: 286 MLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVW 345
L +WPL LG T+ QR++A+ R+ ++ + ++ ++ S +GE+ F+++
Sbjct: 299 RL--LWPLTGLGKTLDLYQRAMASTQRVMQLLATPIQAHPGELSLHPSQVQGELVFQNIS 356
Query: 346 LTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAK 405
Y VLK VS +V G+ + I G GSGKS+++KL+ R Y+ G++L+DGV++ K
Sbjct: 357 FAYPHRSAVLKNVSLRVPAGQTIGIVGATGSGKSTLVKLLLRLYEWDSGDILLDGVDLKK 416
Query: 406 IKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGY 465
+LR+ V V Q+ F+F+ ++RENIA +AT ++ERAA +A+ +FI LP+GY
Sbjct: 417 YFLGDLRRSVGLVSQDVFLFHGTVRENIAYGSADATLAQIERAANLAEAEEFINQLPQGY 476
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
DT++GE+G LSGGQRQR+A+ARA+L NP I++LD+ S +D ETE +V L++I +++
Sbjct: 477 DTIIGERGQKLSGGQRQRLAIARAILKNPPILILDEATSAVDNETEAAIVRSLEKITKNR 536
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
T + ++ RLS V+ D++ V+++G + E G E L+ G+++++ +
Sbjct: 537 TTITIAHRLSTVRYADQIYVLENGMVQEMGSHESLLAHQGLYAKLWR 583
>pir||S77337 ABC-type transport protein sll1725 - Synechocystis sp. (strain PCC
6803) >gi|1652519|dbj|BAA17440.1| (D90906) ABC
transporter [Synechocystis sp.]
Length = 610
Score = 296 bits (750), Expect = 4e-79
Identities = 157/507 (30%), Positives = 279/507 (54%)
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
++++ V + + L + +R + +QR + + + SG LI R+++
Sbjct: 91 VIIIAVSRAIATYWNTVSLAIVGSRVMAQVRDQLYGHLQRLSLRYHYQARSGDLIIRVSS 150
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
D R+ L L+ S+ + + M +++ LT+++L T + + K+R
Sbjct: 151 DANRLQEILLTAALPLVVSLLTLGGMVGVMAWLDLKLTLLSLATFPLFWLAANRLSAKIR 210
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
RHQ G +AS A +++ IK +++LS+E+ FS++N+ N++ ++ A
Sbjct: 211 HASLTQRHQEGAVASTAAESLSAIKLVQALSLEQAFADLFSRQNQRSLQENIETKRLAAN 270
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+++ + + YGG +I++ LT G ++ FLTY+ P++ G + +
Sbjct: 271 LERLVDVLIAFGTALVMGYGGHLVIEDALTAGTVLVFLTYLRNAYKPVQNFAKYTGRLAK 330
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPG 365
+ A+ R+ +++ P D P A+ +G IEF+ V YH + +L G++ V+PG
Sbjct: 331 AAASGERILNILAETPDIQDKPGAIPAPFFQGRIEFKYVSFGYHPDQAILDGLNLTVRPG 390
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
EK+ + G GSGKS++L L+ R Y PT G++ IDG ++ + +LR +A V QE +F
Sbjct: 391 EKIALVGASGSGKSTLLSLLLRLYDPTAGKIFIDGHDLRDYQLTSLRNQMAVVLQESLLF 450
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
+IRENIA AT E+E AA++A H FI LP+GYDTVVGE+G TLSGGQRQR+A
Sbjct: 451 AATIRENIAYGIEGATMAEIEAAARLANAHKFILELPQGYDTVVGERGTTLSGGQRQRLA 510
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+ARA + I++LD+P S LD E+ + E L+ + +++T +V+ L L D+++
Sbjct: 511 IARAAMRQTPILILDEPTSGLDKVNEQLVFEALERLAENRTTFLVTHNLQLAIAADQILY 570
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEMMK 572
+ G+I E G EL+ + G+++++ +
Sbjct: 571 LYQGQIREQGTHAELLARQGVYADLFQ 597
>pir||G69815 ABC transporter (ATP-binding protein) homolog ygaD - Bacillus
subtilis >gi|1673392|emb|CAB04797.1| (Z82044)
unidentified transporter-ATP binding [Bacillus subtilis]
>gi|2633192|emb|CAB12697.1| (Z99108) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 589
Score = 295 bits (747), Expect = 1e-78
Identities = 171/572 (29%), Positives = 309/572 (53%), Gaps = 21/572 (3%)
Query: 4 SINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAID---KGVSTGAYKVAI 60
++ + R + +++ + + + + I+ +P+L++ +D +G T + K
Sbjct: 9 TVGVMKRYMQFVKPYKKQIFVTVLIGIVKFSIPLALPLLLKYVVDDIIQGGGTASDKTTS 68
Query: 61 RYGLLILLVG---VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSG 117
+ ++ ++ +L +Y A +Y +R F IQ+ + F+ T +G
Sbjct: 69 LFTIMAIMFALFLILRPPVEYYRQYFAQWTASKVLYDIRAKLFDHIQKLSLRFYANTRTG 128
Query: 118 QLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLN 177
++ISR+ ND E+ F+ + + + I+I + M+ +++ LT+++++ +
Sbjct: 129 EVISRVINDVEQTKDFVITGLMNIWLDMLTILIVISIMLTLDVKLTLISIVLFPL----- 183
Query: 178 TTYAMKVRPIYDKIRHQT-------GVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE 230
Y + V+ Y ++R T + I G+ I+S ++E++ Q +F+++N
Sbjct: 184 --YGISVKYFYGRLRKLTRERSQALAQVQGHLHERIQGMPVIRSFAIEDHEQAQFNEKNG 241
Query: 231 ELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM 290
++ A + LA + G +I LTVG +VAF+ Y+ M
Sbjct: 242 HFLDKAIRHTNWNAKTFAVVNTITDLAPLIVIACAGYFVINGPLTVGTMVAFVGYIDRMY 301
Query: 291 WPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT 350
P+R L + + +S+A+ R+F+ ID + D P+A++ RG +EF++V Y
Sbjct: 302 NPVRRLINSSTTLTQSIASMDRVFEFIDEPYELTDKPNAIKADQIRGGVEFQNVSFQYEK 361
Query: 351 GR-TVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTE 409
+ +L VS KV GE V + G G GKS+++ LI RFY T G +LIDG ++ +
Sbjct: 362 DKENILHDVSLKVNRGETVALVGMSGGGKSTLVSLIPRFYDVTSGRLLIDGTDIRDYEAR 421
Query: 410 NLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
+LR V V Q+ F+F+ +IRENIA+ KP+AT EE+ AAK A H+FI S P+GY+T V
Sbjct: 422 SLRNQVGMVLQDTFLFSETIRENIAIGKPDATLEEIIEAAKAANAHEFIMSFPEGYETRV 481
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
GE+G+ LSGGQ+QRI++AR L NP +++LD+ S LD E+E + E + ++ +D+T +
Sbjct: 482 GERGVKLSGGQKQRISIARVFLKNPPLLILDEATSALDLESEHYIQEAMDKLAKDRTTFV 541
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI 561
V+ RLS + D+++VM++G I+E G +EL+
Sbjct: 542 VAHRLSTITHADKIVVMENGTIIEIGTHDELM 573
>gb|AAD53033.1|AF115536_1 (AF115536) TAP1 protein [Oncorhynchus mykiss]
Length = 739
Score = 294 bits (746), Expect = 1e-78
Identities = 169/578 (29%), Positives = 317/578 (54%), Gaps = 15/578 (2%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
+K+ L +L+ Y++ + + F L L+++ S +P D ++ +
Sbjct: 138 KKTGASLEKLMGYMKPYFIRFGAVLSLVVISSLGEMAIPHYTGRMTDWIINKDEPEAFTH 197
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
++ L+ V++ V + ++ F+++ + E+ FFD +G L+S
Sbjct: 198 AITVMSLIKVMSVVCEFVCDLIYNITMSRIHTSIQGLVFQSVLKQEIAFFDTAQTGDLVS 257
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
RIT DT ++ LS ++ +L++ + +M+ ++ L++ + + I+ +
Sbjct: 258 RITTDTNDMSESLSEKLSLLMWYFMRVTFLFIFMLNLSWKLSLFTAMGLPIIWVIPKISG 317
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ + K++ +AT T + +KT++S + EE + + E+ YSLN +
Sbjct: 318 KWYQELGAKVQKSLAQANDVATETFSSMKTVRSFANEEGETEHYRKRLEKTYSLNKEE-- 375
Query: 242 ITALYGNAPFLVLGLAMSTMF------YYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
A Y + + +MS++F YYGG + T++ G+LVAF+ Y L + A
Sbjct: 376 -AAAYAASTWTN---SMSSLFLKVSILYYGGSLVTGGTVSSGDLVAFVLYELQFSSAVEA 431
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-- 353
+ + R++ + ++F+ +D P+ + P + N G +EF++V TY T
Sbjct: 432 VMSYYPSVMRAIGGSEKIFEYVDRQPQ-VPPEGTLAPQNLEGHVEFKNVTFTYPTREDTP 490
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VLKG+S +++PG+ + G G+GKS+ + L+ RFY P +GE+L+DG + K + L
Sbjct: 491 VLKGLSLELRPGQITALVGASGAGKSTCVSLLERFYLPQEGEILLDGQPLHSYKNQYLHD 550
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
++ V QEP +F RS++ENI + +AT EE+ RAA++A H FI+ LP GYDT GEKG
Sbjct: 551 KISVVSQEPVLFARSVKENIKYGRDDATDEEMYRAAELANAHKFISDLPNGYDTDAGEKG 610
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+SGGQ+QRIA+ARA++ P+I++LDD SNLD E+E + + L + + L+++ +
Sbjct: 611 GQVSGGQKQRIAIARALIRKPRILVLDDATSNLDTESEHLVHQALLKDSNPCSVLLIAHK 670
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
LS V+ + ++V+++GK++E+G EL++KGG +++++
Sbjct: 671 LSTVEKANHIVVLEEGKVLEEGSHVELLEKGGTYADLV 708
>pir||G75321 ABC transporter, ATP-binding protein, MsbA family - Deinococcus
radiodurans (strain R1)
>gi|6459844|gb|AAF11602.1|AE002041_6 (AE002041) ABC
transporter, ATP-binding protein, MsbA family
[Deinococcus radiodurans]
Length = 619
Score = 293 bits (743), Expect = 3e-78
Identities = 174/593 (29%), Positives = 315/593 (52%), Gaps = 34/593 (5%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAID-------KGVSTGAYKVAIRY 62
R++ YL + G+ L +L + + +L R AID G +T A A+
Sbjct: 19 RIIGYLGPYKTLAAAGVLLALLTAALQPLPTLLQRYAIDHYLVPYTNGSNTDA--AALYQ 76
Query: 63 GLLILLVG-----VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSG 117
GL ++++G VL V + + Q + +R D F +QR + +FD+ G
Sbjct: 77 GLTMVVLGYVALRVLEFVLTYLSTITVGYLGQNVLRDIRADVFGKLQRLHLRYFDQNPVG 136
Query: 118 QLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLN 177
+LI+R+T+D + I +F++ + ++ S FLII+ + M+ +N L ++A + ++
Sbjct: 137 RLITRVTSDVDAINQFITGGLISMMTSTFLIIVFMTVMLTINWRLALIAFTVLPVLFYAT 196
Query: 178 TTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
+ K+R + + R Q ++ S I G+ T++ E F N L +
Sbjct: 197 NFFRGKLREAFRETRTQQAIVNSKLNENITGMLTVQLFGRERRSALDFDHSNRALLTSLE 256
Query: 238 KAMKITALYGNAPFLVLGLAMSTMFYYGGKAII---------QNTLTVGELVAFLTYMLT 288
++K +L+ ++ +A++ + Y+ + I+ ++VG L AF+ +
Sbjct: 257 NSVKWFSLFMPTVAVLGQVAIALVLYFAARQILGVDVVGTGTAAAISVGTLFAFVQWTQQ 316
Query: 289 MMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY 348
+ P++ L ++Q + A++ R+F V+D+ + D PDA + N RG+++F VW Y
Sbjct: 317 LFQPIQDLADVFNNLQAATASSERIFGVLDTEEEITDKPDAKTLVNFRGQVDFDRVWFAY 376
Query: 349 ----------HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLI 398
R +L+ ++PGE V + G G+GK+S+ L++RFY +G V +
Sbjct: 377 SEDVTAQTPDEDDRWILRDFDLHIQPGESVALVGATGAGKTSVTALVSRFYDVQRGAVRV 436
Query: 399 DGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFI 458
DG +V ++ +LR+ V V Q+ F+F +I N+ L P + V A + +HD+I
Sbjct: 437 DGTDVRDLQQHDLRRHVGVVLQDVFLFAGTIESNLTLDNPAIPHDRVVEACQYVGVHDYI 496
Query: 459 ASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVL-LDDPVSNLDAETEKKLVED 517
SL GY T V E+G TLS GQ+Q +A ARA++ NP I+L LD+ +N+D ETE ++ +
Sbjct: 497 LSLENGYQTEVRERGATLSTGQKQLLAFARALIQNPDILLVLDEATANVDTETELRIQDA 556
Query: 518 LKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
LK+++Q +T++I++ RLS ++ DR+IVM+ G+IVE G +LI +GG ++++
Sbjct: 557 LKKVMQGRTSIIIAHRLSTIEHCDRIIVMRRGRIVEQGTHAQLIAQGGYYAKL 609
>pir||B83022 transport protein MsbA PA4997 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9951282|gb|AAG08382.1|AE004912_8
(AE004912) transport protein MsbA [Pseudomonas
aeruginosa]
Length = 603
Score = 292 bits (740), Expect = 6e-78
Identities = 177/586 (30%), Positives = 312/586 (53%), Gaps = 19/586 (3%)
Query: 4 SINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGA-------- 55
S+ RLL Y++ + FL+ + ++ + T ++ +++ +D + A
Sbjct: 12 SLKIYFRLLGYVKPYIGMFLLSIVGFLIFASTQPMLAGILKYFVDGLSNPDAALFPNVQW 71
Query: 56 -----YKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEF 110
+ LLI+L+ G+ S G + L K + V+ LR+ F + +
Sbjct: 72 PWLRDLHLVYAVPLLIILIAAWQGLGSFLGNFFLAKVSLGLVHDLRVALFNKLLVLPNRY 131
Query: 111 FDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITI 170
FD SG LISRIT + +T + +++++ ++ Y++ MN LT+V L +
Sbjct: 132 FDTHSSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVFLFLYLLWMNWKLTLVMLAIL 191
Query: 171 AIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE 230
++ + TT + K R KI+ G + +A+ TI G + ++S E + +F ++
Sbjct: 192 PVIAVMVTTASRKFRKQSKKIQVAMGDVTHVASETIQGYRVVRSFGGEAYEEKRFLDASQ 251
Query: 231 ELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM 290
++ K A+Y LV+ +AM+ + + ++ + G+LVA++T +
Sbjct: 252 SNTDKQLRMTKTGAVYTPMLQLVIYVAMAILMFL--VLWLRGDASAGDLVAYITAAGLLP 309
Query: 291 WPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH- 349
P+R L +QR +A A +F+ +D A + + VE G +E R++ Y
Sbjct: 310 KPIRQLSEVSSTVQRGVAGAESIFEQLDEAAE--EDQGTVEKERVSGRLEVRNLSFRYPG 367
Query: 350 TGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTE 409
T + VL +SF +PG+ + + G GSGKS++ L+ RFY+ G++L+DGV V +
Sbjct: 368 TDKQVLDDISFIAEPGQMIALVGRSGSGKSTLANLVPRFYQHNDGKILLDGVEVEDYRLR 427
Query: 410 NLRKIVAYVPQEPFIFNRSIRENIALAK-PNATQEEVERAAKIAKIHDFIASLPKGYDTV 468
NLR+ +A V Q+ +FN S+ NIA A +EE+ERAAK A +FI +LP+G+DT
Sbjct: 428 NLRRHIALVTQQVTLFNDSVANNIAYGDLAGAPREEIERAAKAANAKEFIDNLPQGFDTE 487
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
VGE G+ LSGGQRQR+A+ARA+L + +++LD+ S LD E+E+ + L E+++ +T L
Sbjct: 488 VGENGVLLSGGQRQRLAIARALLKDAPLLILDEATSALDTESERHIQAALDEVMKGRTTL 547
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
+++ RLS ++ D ++VM G+IVE G EL+ + G ++ + G
Sbjct: 548 VIAHRLSTIEKADLILVMDQGQIVERGSHAELLAQNGHYARLHAMG 593
>dbj|BAB04534.1| (AP001509) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 611
Score = 290 bits (734), Expect = 3e-77
Identities = 176/574 (30%), Positives = 306/574 (52%), Gaps = 16/574 (2%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAID----KGVSTGAYKVAIRYG 63
L R+ +YL + L+ ++L S + P +I AID +G ++ +KV I G
Sbjct: 36 LRRIWTYLVNYRGRLLLVFLAVLLSSVLGLLGPFVIGMAIDHYLVEGDTSSLFKVMI--G 93
Query: 64 LLILLVGVLNGVFSLA---GRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
LL + V+SL+ + ++ AQ VY +R D F R + FFDK G+L+
Sbjct: 94 LLAIYA-----VYSLSMWLQQVWMIGIAQQTVYSIRSDLFHHFHRLPIPFFDKKQHGELM 148
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
SR+TND E I+ L+ V + S+ ++ + M+ ++ +T++ + + ++V
Sbjct: 149 SRMTNDIENISNTLNSSVIKIFSSVLTLVGIMIVMLWLSPLMTVITMTVVPLMVFGLKWI 208
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
+ + + + G + T++G I++ S E FS++N EL + + A
Sbjct: 209 TRRTAVFFKQQQKALGDLNGYIEETVSGQSVIQAFSREGAAIATFSEKNRELKTTSFWAQ 268
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
T ++ L + + GG ++ ++T+G +V F Y PL L
Sbjct: 269 TYTGFIPKVMNVLNSLNFAVIAGVGGILAMRGSITIGIIVIFAEYARQFTRPLNDLANQF 328
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSF 360
+ ++A A R+FD++D + ++ + +GE+ F V +Y +T L +SF
Sbjct: 329 NMLLAAIAGAERVFDILDEQEER-HHDQTKQVKSIKGEVSFEQVSFSYEQ-KTTLNNLSF 386
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
V PGE V + GP G+GK++I++L++RFY+ G + +DG +V E+ R+ +A+V Q
Sbjct: 387 HVNPGETVALIGPTGAGKTTIIRLLSRFYEWDGGAIYVDGEDVTTWDRESYRRHLAFVLQ 446
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
E F+F +IRENI + AT EEVE AAK+A H FI LP YDTV+ G +S GQ
Sbjct: 447 ESFLFQGTIRENIRYGRLEATDEEVEAAAKMANAHSFIMRLPDQYDTVLDSDGSGISQGQ 506
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
+Q +++ARAM+ NP I++LD+ SN+D TE + E L ++ +T+ +++ RL+ ++
Sbjct: 507 KQLLSIARAMIANPSILILDEATSNIDTITELNIQEALHRLMNGRTSFVIAHRLNTIQHA 566
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
D ++V++ G +VE G EEL+ K G++ +M+ G
Sbjct: 567 DVILVLEKGTLVEQGSHEELMAKKGVYYDMIDRG 600
>gb|AAB52482.1| (U97407) Contains similarity to Pfam domain: PF00005 (ABC_tran),
Score=419.6, E-value=9.4e-123, N=2 [Caenorhabditis
elegans]
Length = 1289
Score = 289 bits (732), Expect = 6e-77
Identities = 180/522 (34%), Positives = 291/522 (55%), Gaps = 12/522 (2%)
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
++Y + L++GVL S A+ V+ LR + +AI R ++++FDK +G L
Sbjct: 111 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNL 170
Query: 120 ISRITNDTERITRFLSFRVRML--LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLN 177
+R+T+D ER+ L + +L +++ FL + + ++TL M+ + ++ G
Sbjct: 171 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 230
Query: 178 TTYAMKVRPIYDKIRHQTGVIA-SIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLN 236
+ +M R ++ +T +A +IA T + I+T+ SL+ + +F E
Sbjct: 231 MSKSMATRT---RVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 287
Query: 237 VKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQN-TLTVGELVAFLTYMLTMMWPLRA 295
+ + L + + + F+YG II + T G + +L+ L
Sbjct: 288 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGG 347
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPP--DAVEISNPRGEIEFRDVWLTYHTGRT 353
+ + AAS + VI+S PK IDP + + + N +G+I F+DV Y + +
Sbjct: 348 ALPHLASFGTARGAASTVLRVINSHPK-IDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 406
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VLKG+S ++K G+K+ + G G GKS+I+ L+ RFY PTKG VLIDGV++ ++ +L
Sbjct: 407 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 466
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGE 471
R+ + V QEP +F+ +I ENI + +AT ++V A K+A +DFI LP GY T VGE
Sbjct: 467 REQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGE 526
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
KG+ LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD E E+++ L + +T +IV+
Sbjct: 527 KGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVA 586
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
RLS ++ VDR+ V K G IVE G EEL+ K GIF +M +A
Sbjct: 587 HRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTQA 628
Score = 237 bits (598), Expect = 3e-61
Identities = 167/523 (31%), Positives = 275/523 (51%), Gaps = 32/523 (6%)
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISR 122
+ +L+G+ V L + + LR +AF+ + R ++ F+D + +G+L +R
Sbjct: 770 MFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTR 829
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLII----ISLYYMVRMNITLT-MVALITIAIVVGLN 177
D + R++ R+ ++L SI I I YY ++ + L MV L+ + +
Sbjct: 830 FATDAPNV-RYVFTRLPVVLASIVTICGALGIGFYYGWQLALILVVMVPLLVMGGYFEMQ 888
Query: 178 TTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
+ ++R ++ + G +AS A + I+T+ SL+ +E + + E ++ N+
Sbjct: 889 MRFGKQIRDT--QLLEEAGKVASQA---VEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 943
Query: 238 KAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALG 297
K YG V + S +F+ A ++ V + + + + + G
Sbjct: 944 KHAHT---YG----AVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 996
Query: 298 FTIG-------DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP-RGEIEFRDVWLTYH 349
IG D+ ++ AAS LF +I+ P ID I P G I R+V+ Y
Sbjct: 997 QMIGNTTSFIPDVVKARLAASLLFYLIEH-PTPIDSLSDSGIVKPITGNISIRNVFFNYP 1055
Query: 350 TGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIK 407
T + VL+G + +K G+ V + G G GKS+I+ L+ RFY KG ++IDG N+ +
Sbjct: 1056 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 1115
Query: 408 TENLRKIVAYVPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYD 466
+LR+ V V QEP +F+ +I ENI N T +E+ AAK+A IH+FI LP GYD
Sbjct: 1116 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 1175
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T VGEKG LSGGQ+QRIA+ARA++ +P ++LLD+ S LD E+EK + E L Q +T
Sbjct: 1176 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 1235
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSE 569
L+++ RLS ++ D + ++ +GKIVE G +ELI+K I+ +
Sbjct: 1236 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQK 1278
>gi|9955966 ATP-binding cassette, sub-family B, member 9, isoform 2 [Homo
sapiens] >gi|9588085|dbj|BAA97989.2| (AB045381) TAPL
[Homo sapiens] >gi|9622987|gb|AAF89993.1|AF216494_1
(AF216494) ATP-binding cassette protein ABCB9 [Homo
sapiens]
Length = 766
Score = 289 bits (731), Expect = 7e-77
Identities = 172/579 (29%), Positives = 306/579 (52%), Gaps = 27/579 (4%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGV---STGAYKVAIRYGL 64
L +LLSY + + F +I+ + + +P AID V S + A+
Sbjct: 174 LQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVC 233
Query: 65 LILL-----VGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
L+ + G+ G+F+L L ++ LR FR++ E FFD+ +G L
Sbjct: 234 LLAIGSSFAAGIRGGIFTLIFARLNIR--------LRNCLFRSLVSQETSFFDENRTGDL 285
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
ISR+T+DT ++ +S + + L + + + +M ++ L++V + I++ ++
Sbjct: 286 ISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNI 345
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
Y + + ++++ ++ A TI+ +KT++S + EE + ++ +++Y LN K
Sbjct: 346 YGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKE 405
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
Y L L + ++ YYGG +I +T G L+AF+ Y + + ++G
Sbjct: 406 AAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSV 465
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDP----PDAVEISNPRGEIEFRDVWLTYHTG--RT 353
+ + + AA ++F+ ID P + PD +E G ++F +V TY T
Sbjct: 466 YSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLE-----GRVDFENVTFTYRTRPHTQ 520
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VL+ VSF + PG+ + GP GSGKSS + ++ FY G VL+DG ++ + L +
Sbjct: 521 VLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHR 580
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+++ V QEP +F RSI +NI+ P E V AA+ A H FI L GY T GEKG
Sbjct: 581 VISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKG 640
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
LSGGQ+QR+A+ARA++ NP +++LD+ S LDAE+E + + + LQ T LI++ R
Sbjct: 641 AQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHR 700
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
LS V+ ++V+ G++V+ G ++L+ +GG+++++++
Sbjct: 701 LSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQ 739
>gi|11560034 TAP-like ABC transporter [Rattus norvegicus]
>gi|6045150|dbj|BAA85306.1| (AB027520) TAP-like ABC
transporter [Rattus norvegicus]
Length = 762
Score = 288 bits (730), Expect = 9e-77
Identities = 173/579 (29%), Positives = 304/579 (51%), Gaps = 27/579 (4%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGV---STGAYKVAIRYGL 64
L +LLSY + + F +I+ + + +P AID V S + A+
Sbjct: 170 LQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQFTTAVVVVC 229
Query: 65 LI-----LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
L+ L G+ G+F+L L ++ LR FR++ E FFD+ +G L
Sbjct: 230 LLAIGSSLAAGIRGGIFTLVFARLNIR--------LRNCLFRSLVSQETSFFDENRTGDL 281
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
ISR+T+DT ++ +S + + L + + + +M ++ L++V + I++ ++
Sbjct: 282 ISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNI 341
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
Y + + +++ ++ A TI+ +KT++S + EE F ++ +++Y LN K
Sbjct: 342 YGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRKE 401
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
Y L L + ++ YYGG +I ++ G L+AF+ Y + + ++G
Sbjct: 402 AAAYMSYVWGSGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVGSV 461
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDP----PDAVEISNPRGEIEFRDVWLTYHTG--RT 353
+ + + AA ++F+ ID P + PD +E G ++F +V TY T
Sbjct: 462 YSGLMQGVGAAEKVFEFIDRQPTMVHDGRLAPDHLE-----GRVDFENVTFTYRTRPHTQ 516
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VL+ VSF + PG+ + GP GSGKSS + ++ FY G VL+DG + + L +
Sbjct: 517 VLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLQGGRVLLDGEPIGAYDHKYLHR 576
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+++ V QEP +F RSI +NI+ P E V AA+ A H FI L GY T GEKG
Sbjct: 577 VISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKG 636
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
LSGGQ+QR+A+ARA++ NP +++LD+ S LDAE+E + + + LQ T LI++ R
Sbjct: 637 AQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHR 696
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
LS V+ ++V+ G++V+ G ++L+ +GG+++++++
Sbjct: 697 LSTVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQ 735
>dbj|BAA97990.2| (AB045382) TAPL [Mus musculus]
Length = 762
Score = 288 bits (730), Expect = 9e-77
Identities = 173/579 (29%), Positives = 304/579 (51%), Gaps = 27/579 (4%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGV---STGAYKVAIRYGL 64
L +LLSY + + F +I+ + + +P AID V S + A+
Sbjct: 170 LQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQFTTAVVVVC 229
Query: 65 LI-----LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
L+ L G+ G+F+L L ++ LR FR++ E FFD+ +G L
Sbjct: 230 LLAIGSSLAAGIRGGIFTLVFARLNIR--------LRNCLFRSLVSQETSFFDENRTGDL 281
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
ISR+T+DT ++ +S + + L + + + +M ++ L++V + I++ ++
Sbjct: 282 ISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNI 341
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
Y + + +++ ++ A TI+ +KT++S + EE F ++ +++Y LN K
Sbjct: 342 YGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRKE 401
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
Y L L + ++ YYGG +I ++ G L+AF+ Y + + ++G
Sbjct: 402 AAAYMSYVWGSGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVGSV 461
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDP----PDAVEISNPRGEIEFRDVWLTYHTG--RT 353
+ + + AA ++F+ ID P + PD +E G ++F +V TY T
Sbjct: 462 YSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLE-----GRVDFENVTFTYRTRPHTQ 516
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VL+ VSF + PG+ + GP GSGKSS + ++ FY G VL+DG + + L +
Sbjct: 517 VLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLQGGRVLLDGKPIGAYDHKYLHR 576
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+++ V QEP +F RSI +NI+ P E V AA+ A H FI L GY T GEKG
Sbjct: 577 VISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKG 636
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
LSGGQ+QR+A+ARA++ NP +++LD+ S LDAE+E + + + LQ T LI++ R
Sbjct: 637 AQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHR 696
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
LS V+ ++V+ G++V+ G ++L+ +GG+++++++
Sbjct: 697 LSTVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQ 735
>pir||T27215 hypothetical protein Y57G11C.1 - Caenorhabditis elegans
>gi|3881178|emb|CAB16503.1| (Z99281) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=227.6,
E-value=5.9e-65, N=1; PF00664 (ABC transporter
transmembrane region.), Score=121.7, E-value=4.5e-33,
N=1 [Caenorhabditis elegans]
Length = 633
Score = 288 bits (729), Expect = 1e-76
Identities = 155/553 (28%), Positives = 299/553 (54%), Gaps = 4/553 (0%)
Query: 22 FLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGR 81
F+ L+IL N I P L + + ++ + R LL+ L+ A
Sbjct: 57 FVPAYTLLILDCALNLIEPALYGQMMTNAIQMKSFDIIKRACLLLALIQFSEATCKSACY 116
Query: 82 YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRML 141
+ + A + +R+ FR+I E+ FFD+ +GQL+SRIT+D+E I+ L + L
Sbjct: 117 FFMQYAEKLTARNIRIQLFRSILHQEISFFDENKTGQLVSRITHDSESISNTLPVHIETL 176
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
+ ++F+ S+ M + LT+ + I I + + Y + V + +K T
Sbjct: 177 VNNLFMFFGSIPIMFCYSWQLTLTSFIEFPITLLMTRYYGLAVEKLSEKENDATAASNET 236
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTM 261
++ I+T++S + E Q ++++ E+ + ++ K + + +Y L+L
Sbjct: 237 VEEVLSAIRTVRSFAAENFEQKRYTKNTEDWFKISTKTVTLGTIYNYFWALMLRSQDVIR 296
Query: 262 FYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP 321
+ YGG + + L+ F+ Y + + A + +++ + ++ +I+ P
Sbjct: 297 YLYGGYLALNGRMAPEALLTFIFYHWRLHTAINAFSSLFSGVMKTIGLSRKVIHLINRKP 356
Query: 322 KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKS 379
+ +D E +G+IEF V Y T +TV + G++ ++ G+ V + GP G+GKS
Sbjct: 357 Q-LDYDFGTETPEIQGKIEFEVVEFAYPTRKTVNVINGINLSIESGKTVALVGPSGNGKS 415
Query: 380 SILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPN 439
+++ LI +FY P G +L DG+ + I ++ +A V QEP +F+ +IRENI N
Sbjct: 416 TLVSLIQQFYTPQSGRILTDGIPIQNINHQHYHSNIALVAQEPTLFSGTIRENILFGIEN 475
Query: 440 ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLL 499
T+E + +AA++A +H+F++ + GYDT GEKG+ +SGGQ+QRIA+ARA++ NP++++L
Sbjct: 476 GTEEAMLKAAEMANVHEFVSKMDDGYDTKCGEKGVQMSGGQKQRIAIARALIRNPRVLIL 535
Query: 500 DDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEE 559
D+ S LD+E+E + E L + +++T ++++ RLS V+ ++ V+++G + E G +E
Sbjct: 536 DEATSALDSESEGMVQEALNKCAKERTVIVIAHRLSTVRKAQKIAVIENGSVKEMGCHDE 595
Query: 560 LIK-KGGIFSEMM 571
L++ + G++ +++
Sbjct: 596 LMENQDGLYYKLV 608
>gi|9845230 ATP-binding cassette, sub-family B, member 9 [Mus musculus]
>gi|9622989|gb|AAF89994.1|AF216495_1 (AF216495)
ATP-binding cassette protein ABCB9 [Mus musculus]
Length = 762
Score = 288 bits (729), Expect = 1e-76
Identities = 173/579 (29%), Positives = 304/579 (51%), Gaps = 27/579 (4%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGV---STGAYKVAIRYGL 64
L +LLSY + + F +I+ + + +P AID V S + A+
Sbjct: 170 LQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQFTTAVVVVC 229
Query: 65 LI-----LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
L+ L G+ G+F+L L ++ LR FR++ E FFD+ +G L
Sbjct: 230 LLAIGSSLAAGIRGGIFTLVFARLNIR--------LRNCLFRSLVSQETSFFDENRTGDL 281
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
ISR+T+DT ++ +S + + L + + + +M ++ L++V + I++ ++
Sbjct: 282 ISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNI 341
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
Y + + +++ ++ A TI+ +KT++S + EE F ++ +++Y LN K
Sbjct: 342 YGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRKE 401
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
Y L L + ++ YYGG +I ++ G L+AF+ Y + + ++G
Sbjct: 402 AAAYMSYVWGSGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVGSV 461
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDP----PDAVEISNPRGEIEFRDVWLTYHTG--RT 353
+ + + AA ++F+ ID P + PD +E G ++F +V TY T
Sbjct: 462 YSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLE-----GRVDFENVTFTYRTRPHTQ 516
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VL+ VSF + PG+ + GP GSGKSS + ++ FY G VL+DG + + L +
Sbjct: 517 VLQNVSFSLSPGKVTALVGPSGSGKSSCVNILESFYPLQGGRVLLDGKPIGAYDHKYLHR 576
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+++ V QEP +F RSI +NI+ P E V AA+ A H FI L GY T GEKG
Sbjct: 577 VISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKG 636
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
LSGGQ+QR+A+ARA++ NP +++LD+ S LDAE+E + + + LQ T LI++ R
Sbjct: 637 AQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHR 696
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
LS V+ ++V+ G++V+ G ++L+ +GG+++++++
Sbjct: 697 LSTVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQ 735
>pir||S76668 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1001774|dbj|BAA10612.1| (D64004) ABC transporter
[Synechocystis sp.]
Length = 580
Score = 287 bits (728), Expect = 2e-76
Identities = 178/574 (31%), Positives = 311/574 (54%), Gaps = 16/574 (2%)
Query: 4 SINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYG 63
S+ QL+R YL H G F + L + +P+L+R++ID + R
Sbjct: 5 SVKQLLR---YLTPHWRAIGAGTFALFLANALGVYIPILMRDSIDDLMPPFEASDVARIV 61
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
+LI+++ L +A R L+ + Y L+ F + + E +F + G LI+R
Sbjct: 62 VLIVVLASLMWFIRMASRILIFGVGRQVEYELKQKIFDHLLKLEPLYFTENTIGDLINRA 121
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
T+D + I R + F V L+ ++F +++ M ++I LT++A+ +++ ++ K
Sbjct: 122 TSDVDNIRRLVGFAVLSLINTVFAYALTIPAMFALHIPLTLLAVSVYPLMLMSVNLFSGK 181
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
+R +++ + ++ + ++GI IK S E+N + F N++L N+K +I
Sbjct: 182 LRDYQLEVQEELSALSELVQEDMSGISLIKIYSQEDNERQAFQTRNQKLLQANLKLARIR 241
Query: 244 ALYGNAPF-LVLGLAMSTMFY---YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
N F L+ GLA ++ +G I ++T+G+ +A + + +++P LGFT
Sbjct: 242 ----NFLFPLIEGLAYLSLLILLAFGTGLIQDGSITIGDFIALIILVERLVFPTALLGFT 297
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPR--GEIEFRDVWLTYH-TGRTVLK 356
I QR + R+ + + PK + P + S + G+I R + Y + L+
Sbjct: 298 ITAYQRGEVSIQRVEAIFHTTPKILTVPQPLPFSPAQATGKITARGLNYCYPGSDLPALE 357
Query: 357 GVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVA 416
V F V PGE V I GP GSGKS+++ ++ R G+V ID ++ +I +LR +A
Sbjct: 358 QVDFTVYPGEMVAIVGPIGSGKSTLVNVLPRLLDIAPGQVFIDDYDITQIALSDLRSAIA 417
Query: 417 YVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
+VPQE F+F+ +I ENIA + P+ T +E+AA A + IA+ P+ Y T+VGE+GITL
Sbjct: 418 FVPQESFLFSTTIAENIAYSDPSQTDTAIEQAAHQAHLDQEIANFPQHYQTLVGERGITL 477
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSL 536
SGGQRQR ALARA++++ +++LDD +S++D +T +++ L ++ T L VS +LS
Sbjct: 478 SGGQRQRAALARALILDAPLLVLDDALSSVDNQTATRILHYLAR--RNNTVLFVSHQLSA 535
Query: 537 VKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
DR+ VM G+IV+ G EEL+++ G++ +
Sbjct: 536 AAQADRIFVMDHGRIVQTGSHEELLQQSGLYQSL 569
>pir||G70837 probable ABC transporter Rv0194 - Mycobacterium tuberculosis
(strain H37RV) >gi|2909592|emb|CAA17316.1| (AL021928)
hypothetical protein Rv0194 [Mycobacterium tuberculosis]
Length = 1194
Score = 287 bits (728), Expect = 2e-76
Identities = 176/566 (31%), Positives = 301/566 (53%), Gaps = 11/566 (1%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
RL Y+ H L+G + + +VP++ + ID ++ +A +L+
Sbjct: 8 RLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIAADHRPLAPWAVVLVAAA 67
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
G + RY + A + LRMDAF+A+ R + D+ SGQLI R TND +
Sbjct: 68 GATY-LLMYVRRYYGGRIAHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQL 126
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ L F V +L + +++ + M +++ L ++A++ + V+GL A + R +
Sbjct: 127 VQALL-FDVPNVLRHVLTLLLGVAVMTWLSVPLALLAVLLVP-VIGL---IAHRSRRLLA 181
Query: 190 KIRH----QTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
H + + + GI+ +K+ EE K + LY+ ++ ++ A
Sbjct: 182 AATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAH 241
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+G + L +F GG Q ++TVG VAF + + P L + Q+
Sbjct: 242 FGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQQ 301
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPG 365
+ A A R+ ++IDS P +D + R +EF+ V Y R VL+ +S V+ G
Sbjct: 302 ARAGAVRVLELIDSRPTLVDGTKPLS-PEARLSLEFQRVSFGYVADRPVLREISLSVRAG 360
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
E + + G PGSGKS++ L R Y T+G V I G +V ++ ++LR + VP++ +F
Sbjct: 361 ETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLDSLRSAIGLVPEDAVLF 420
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
+ +I NIA +P+AT E++ AA+ A I +F+ +LP GY T VG +G+TLSGGQRQRIA
Sbjct: 421 SGTIGANIAYGRPDATPEQIATAARAAHIEEFVNTLPDGYQTAVGARGLTLSGGQRQRIA 480
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
LARA+L P+++++DDP S +DA E + E L+E + D+TA+I ++R S++ L DRV V
Sbjct: 481 LARALLHQPRLLIMDDPTSAVDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAV 540
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEMM 571
+ G++++ G P+E+ ++ + E++
Sbjct: 541 LDSGRLLDVGTPDEVWERCPRYRELL 566
Score = 250 bits (631), Expect = 4e-65
Identities = 159/567 (28%), Positives = 274/567 (48%), Gaps = 6/567 (1%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
L RLL RG + L L+ + + + P+LIR+ ID G+ L
Sbjct: 616 LRRLLREFRGPLA---LSLLLVAVQTCAGLLPPLLIRHGIDVGIRRHVLSALWWAALAGT 672
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
V+ V + + ++ LR F QR ++ F+ Q+++ +T D
Sbjct: 673 ATVVIRWVVQWGSAMVAGYTGEQVLFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADV 732
Query: 128 ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
E I FL + + + S+ ++ L ++ + L ++ T+ ++ +
Sbjct: 733 EAIVAFLRTGLVVAVISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWT 792
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYG 247
Y + RH+ G + + AG++ ++ E + +++ L V+ ++ ALY
Sbjct: 793 YRRARHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYY 852
Query: 248 NAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL 307
L+ LA + + G + + ++VG LV +L Y+ + P+ L D QR+
Sbjct: 853 PFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFDDYQRAA 912
Query: 308 AAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-VLKGVSFKVKPGE 366
AA R+ ++ + S P A + RGE+ F V +Y T L G++ ++ G+
Sbjct: 913 VAAGRIRSLLSTRTPS--SPAARPVGTLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQ 970
Query: 367 KVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFN 426
V+ G GSGKS+++KL+ARFY PT G V +DG ++ + + R + V QE ++F
Sbjct: 971 TVVFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFA 1030
Query: 427 RSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIAL 486
++R+ IA +P+AT +VERAA+ H I +L GY V G LS GQ Q +AL
Sbjct: 1031 GTVRDAIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLAL 1090
Query: 487 ARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVM 546
ARA L++P I+LLD+ LD TE + + +T LIV+ L++ + DR++V+
Sbjct: 1091 ARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADRIVVL 1150
Query: 547 KDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ G +VEDG EL+ GG +S + A
Sbjct: 1151 EHGTVVEDGAHTELLAAGGHYSRLWAA 1177
>dbj|BAB06054.1| (AP001515) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 599
Score = 285 bits (722), Expect = 8e-76
Identities = 174/571 (30%), Positives = 297/571 (51%), Gaps = 16/571 (2%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY----GLL 65
RLLSY + ++ L+ + + + P++++ ID ++ + + + G L
Sbjct: 20 RLLSYAAHYKGQLMVAFLLLFIATGAQLLGPIIVKIFIDDYLTPRYFPTDVLFLLGAGYL 79
Query: 66 IL-LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
+L L V+ + L +L K A V LR+D F ++QR + FFD+T +G L+SRIT
Sbjct: 80 VLHLTAVIIDYYQL---FLFQKVALSIVQRLRIDVFSSVQRLGLSFFDQTPAGGLVSRIT 136
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
NDTE I + + +I +I M +N+TL + L+ + ++ L Y
Sbjct: 137 NDTESIKELYVTVLATFVQNIIFLIGIFAAMFYLNVTLAIYCLVLLPLIFALMQVYRKYS 196
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
Y + + ++ +I G+ I+ E ++ +FS N+E + +K+MK+
Sbjct: 197 SRFYADMSEKLSLLNGRINESIQGMAIIQMFRQERRMRKEFSAINDEHFLAGMKSMKLDG 256
Query: 245 LYGNAPFLVLG-LAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
L VL LA+ + Y G + + +G + AF+ Y+ P+ + +
Sbjct: 257 LLLRPAVDVLSILALMLILSYFGIMSMDTAVEIGVVYAFVNYLDRFFEPVNQMMMRLSMF 316
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNP----RGEIEFRDVWLTYHTGRTVLKGVS 359
Q+++ +A R+F ++D + PD +P G +EFR+V +Y VLK +S
Sbjct: 317 QQAIVSAGRVFKLMDHRELA---PDREGNEHPAIIGEGNVEFRNVSFSYDGKTNVLKNIS 373
Query: 360 FKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVP 419
F VK GE V + G GSGK+SI+ ++ RFY GE+LIDG + + LR V V
Sbjct: 374 FTVKKGETVALVGHTGSGKTSIINVLMRFYPLQDGEILIDGKPLTSFENNELRAKVGLVL 433
Query: 420 QEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
Q+PF++ +I NI L + + ++RAA + FI L GY+T V E+G T S G
Sbjct: 434 QDPFLYTGTIASNIRLYDQAISDDRIKRAASFVRADGFIERLSHGYETKVTERGATFSSG 493
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKL 539
QRQ ++ AR M+ P I++LD+ +++D ETE+ + E L+ + Q +T + ++ RLS +K
Sbjct: 494 QRQLLSFARTMVREPAILILDEATASVDTETEEAIQEALERMKQGRTTIAIAHRLSTIKD 553
Query: 540 VDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
D+++V+ G+IVE G +ELI K G++ +M
Sbjct: 554 ADQILVLHQGEIVERGTHDELIAKKGLYQKM 584
>pir||A69829 ABC transporter (ATP-binding protein) homolog yheI - Bacillus
subtilis >gi|2226166|emb|CAA74450.1| (Y14080)
hypothetical protein [Bacillus subtilis]
>gi|2633306|emb|CAB12810.1| (Z99109) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 585
Score = 285 bits (721), Expect = 1e-75
Identities = 169/561 (30%), Positives = 305/561 (54%), Gaps = 8/561 (1%)
Query: 14 YLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYK---VAIRYGLLILLVG 70
+ + + + + I + L++ ++ P L+ NAID + GA+ + G+ +L
Sbjct: 11 FFKAYWLRYTIAIVLLLAVNVIEMFPPKLLGNAIDD-MKAGAFTAEGLLFYIGIFFVLTA 69
Query: 71 VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERI 130
+ + S + L A LR + F++K +G L++R TND + +
Sbjct: 70 AVY-IMSYFWMHQLFGGANLMEKILRTKLMGHLLTMSPPFYEKNRTGDLMARGTNDLQAV 128
Query: 131 TRFLSFRVRMLLYS-IFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ F + L+ S +F++ I L ++ LT A+I + ++ + Y K+ +
Sbjct: 129 SLTTGFGILTLVDSTMFMMTIFLTMGFLISWKLTFAAIIPLPVMAIAISLYGSKIHERFT 188
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
+ ++ G + +++G++ I++ E N +F++ ++Y N+K I +L+
Sbjct: 189 EAQNAFGALNDRVLESVSGVRVIRAYVQETNDVRRFNEMTADVYQKNMKVAFIDSLFEPT 248
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
L++G + YG + +N LT+GELV+F Y+ M+WP+ A+G I +QR A+
Sbjct: 249 VKLLVGASYLIGLGYGAFLVFRNELTLGELVSFNVYLGMMIWPMFAIGELINVMQRGNAS 308
Query: 310 ASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV-LKGVSFKVKPGEKV 368
R+ + + DP ++ P G+I F V TY + + L+ +SF V+ G+ V
Sbjct: 309 LDRVNETLSYETDVTDPKQPADLKEP-GDIVFSHVSFTYPSSTSDNLQDISFTVRKGQTV 367
Query: 369 LITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRS 428
I G GSGK++I+K + R Y P +G + GV + +I + LR + YVPQ+ +F+R+
Sbjct: 368 GIAGKTGSGKTTIIKQLLRQYPPGEGSITFSGVPIQQIPLDRLRGWIGYVPQDHLLFSRT 427
Query: 429 IRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALAR 488
++ENI K +AT +EV++A A + LP G +T+VGEKG+ LSGGQ+QRI++AR
Sbjct: 428 VKENILYGKQDATDKEVQQAIAEAHFEKDLHMLPSGLETMVGEKGVALSGGQKQRISIAR 487
Query: 489 AMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKD 548
A++ NP+I++LDD +S +DA+TE ++++++E + KT I++ RLS V+ D ++VM
Sbjct: 488 ALMANPEILILDDSLSAVDAKTEAAIIKNIRENRKGKTTFILTHRLSAVEHADLILVMDG 547
Query: 549 GKIVEDGKPEELIKKGGIFSE 569
G I E G +EL+ G + E
Sbjct: 548 GVIAERGTHQELLANNGWYRE 568
>gb|AAG18746.1| (AE004979) ABC transport protein; Trp1 [Halobacterium sp. NRC-1]
Length = 642
Score = 284 bits (720), Expect = 1e-75
Identities = 168/589 (28%), Positives = 307/589 (51%), Gaps = 25/589 (4%)
Query: 6 NQLIRLLS-YLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTG---------A 55
N +++L Y R H+ ++ + + + PVL+ AID + +
Sbjct: 23 NAMVQLFDEYGRDHSFQAVVAVLASVFARVLDLAPPVLLGLAIDSVIQGNKAFLPFLPQS 82
Query: 56 YKVAIRYGLLILLVGVLNGVFSLAGRYLLVKA------AQYAVYYLRMDAFRAIQRHEME 109
+ + L+ + G++ G F L + ++ +Q+ + +R D + +QR M+
Sbjct: 83 VVPSSKPDRLLFMGGLIAGSFLLGAAFHWIRNWGFNSFSQHIQHRVRTDTYDKMQRLNMD 142
Query: 110 FFDKTFSGQLISRITNDTERITRFLSFRVRMLL-YSIFLIIISLYYMVRMNITLTMVALI 168
FF +G+++S ++ND R+ RFL+ + S+ ++ I +Y V +N L ++ ++
Sbjct: 143 FFATKQTGEMMSILSNDVNRLERFLNDGLNSAFRLSVMVLAIGVYLFV-VNWQLAVLTML 201
Query: 169 TIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQE 228
+ I+ + ++P Y +R G + S + GI+ IK+ + E +
Sbjct: 202 PVPIIALFTYRFVNAIQPKYADVRSSVGHLNSRLENNLGGIQVIKTSNTERYESDRVDDV 261
Query: 229 NEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGG-------KAIIQNTLTVGELVA 281
++ + N A+ I + A ++ G+ F GG TL GE V
Sbjct: 262 SQGYFDANWGAITIRIKFFPALRIISGVGFVLTFVIGGIWVATGPPMFFSGTLDPGEFVT 321
Query: 282 FLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEF 341
F+ +WP+ G I QR+ A++ R+F +++ + + PDA E+ G + +
Sbjct: 322 FILLSQQFIWPMAQFGQIINMYQRARASSERIFGLMNEPSRIEENPDADELVVDDGGVVY 381
Query: 342 RDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGV 401
DV Y +++ + F+V G+ + + GP G+GKS++LKL+ R Y G V +DG
Sbjct: 382 DDVRFGYDDDDAIVEHIDFQVDGGDTLALVGPTGAGKSTVLKLLLRMYDVDAGAVRVDGQ 441
Query: 402 NVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASL 461
+++ + +LR+ V YV Q+ F+F ++ ENI +A +E V AAK A+ H+FI +L
Sbjct: 442 DISGVTLPSLRRHVGYVSQDTFLFYGTVEENITYGTFDADREAVVDAAKAAEAHEFIQNL 501
Query: 462 PKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI 521
P GYDT VGE+G+ LSGGQRQRI +ARA+L +P+I++LD+ S++D ETE + L +
Sbjct: 502 PDGYDTEVGERGVKLSGGQRQRIDIARAILKDPEILVLDEATSDVDTETEMLIQRSLDRL 561
Query: 522 LQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+D+T ++ RLS +K D+++V++DG+IVE G +L+ G+++ +
Sbjct: 562 TEDRTTFSIAHRLSTIKDADQIVVLEDGEIVERGTHADLLGDEGLYANL 610
>dbj|BAB07610.1| (AP001520) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 577
Score = 284 bits (718), Expect = 2e-75
Identities = 158/566 (27%), Positives = 291/566 (50%), Gaps = 1/566 (0%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
+ R SY + + F + F + + P+ + ID+ + G +++ + +L
Sbjct: 2 IARFFSYYKPYKGLFFLDFFCAVFVGILELAFPLAVNQVIDRLLPEGNWQIIFWACVGLL 61
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
V +LN V Y K +R F +Q+ ++D +G ISR+T D
Sbjct: 62 FVYLLNTVMQYVVTYWGHKLGINIESDMRKKLFEHMQKLSFGYYDNNKTGHSISRLTKDL 121
Query: 128 ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
E I + ++ ++ + M+ ++ L + + ++ + K+
Sbjct: 122 EEIGEVAHHGPEDVFVAVMTLVGAFAIMLSIHWQLAVALFCVVPFIIIFAVYFNKKMTTT 181
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYG 247
+ ++ G I + +I GI+ +++ + E Q +F++ N+ + + KI A
Sbjct: 182 FRRMFQDVGDINARVEDSIGGIRVVQAFANERYEQAQFAKNNQRYRKTKLASYKIMAQNV 241
Query: 248 NAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL 307
A ++++ G +I +LT GE VAF+ ++ P++ + I + +
Sbjct: 242 MANYVLMRSITLLTLLVGTWFVISGSLTYGEFVAFILLSNILIQPVQKINAVIESYPKGI 301
Query: 308 AAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEK 367
A R +++D+ P D P A E N +G I++ V Y VLK + ++ GE
Sbjct: 302 AGFKRYTEILDTEPDIEDAPGAKEW-NIQGNIQYEGVRFGYDGMEDVLKNIDLTIRAGET 360
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
V GP G+GK+++ L+ RFY+ G +++DG+++ ++K E+LR + V Q+ F+F+
Sbjct: 361 VAFVGPSGAGKTTLCSLLPRFYEVKDGRIVVDGLDIREMKLESLRNQIGIVQQDVFLFSG 420
Query: 428 SIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALA 487
+++ENIA AT EE+ AA+ AK+ DFI S P G +TV+GE+G+ LSGGQ+QR+++A
Sbjct: 421 TVKENIAYGNLQATDEEIMEAARKAKLDDFILSQPDGLETVIGERGVKLSGGQKQRLSIA 480
Query: 488 RAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMK 547
R L NP I++LD+ S LD ETE + + L E+ + +T L+++ RL+ +K DR+IV+
Sbjct: 481 RMFLKNPPILILDEATSALDTETELAIQQSLSELSKGRTTLVIAHRLATIKNADRIIVVT 540
Query: 548 DGKIVEDGKPEELIKKGGIFSEMMKA 573
I E G E+L++ GGI++ + +A
Sbjct: 541 KEGIAEQGSHEQLLQTGGIYARLHRA 566
>gb|AAF67494.1|AF170880_1 (AF170880) NovA [Streptomyces spheroides]
Length = 635
Score = 283 bits (717), Expect = 3e-75
Identities = 172/581 (29%), Positives = 316/581 (53%), Gaps = 18/581 (3%)
Query: 5 INQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGL 64
+ ++ RL RG ++GL L+ S P ++R +D + G + L
Sbjct: 26 LRRIFRLFRPYRGRLA--VVGL-LVGASSLVAVASPFMLREILDTAIPQGRTGLLSLLAL 82
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
++L VL+ VF + + Q ++ LR + +QR + FF +T +G++ SRI
Sbjct: 83 GMILTAVLSSVFGVVQTLISTTVGQRVMHDLRTAVYAQLQRMPLAFFTRTRTGEVQSRIA 142
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
ND + ++ L+ ++ +I ++ M+ ++ LT+V+L+ + + V ++ +
Sbjct: 143 NDIGGMQATVTSTATSLVSNLTAVIATVVAMLALDWRLTVVSLLLLPVFVWISRRVGRER 202
Query: 185 RPIYDKIRHQTGVIASIATG--TIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKI 242
+ I + + Q +A+ T +++GI +++ +++ F++E+E L L V+
Sbjct: 203 KRITLQRQKQMATMAATVTESLSVSGILLGRTMGRADSLTRSFAEESERLVDLEVR---- 258
Query: 243 TALYGNAPFLVLGLAMSTM---FYYGGKAIIQN---TLTVGELVAFLTYMLTMMWPLRAL 296
+ + G V+G+ M+ M Y+ ++Q+ +++G LVAF++ + P +L
Sbjct: 259 SNMAGRWRMSVIGIVMAAMPAVIYWAAGFVLQSGGTVVSIGTLVAFVSLQQGLFRPAVSL 318
Query: 297 GFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH--TGRTV 354
T +Q SLA R+F+ +D +P V + RGE+ F V +Y G T
Sbjct: 319 LPTGVQMQTSLALFQRIFEYLDLPVDITEPERPVALDKVRGEVRFDGVDFSYEEKDGNT- 377
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
L G+ V G + + GP GSGKS++ L+ R Y T G VL+DGV+V + + L +
Sbjct: 378 LHGLDLTVPAGGSLAVVGPTGSGKSTLSYLVPRLYDVTGGRVLLDGVDVRDLAFDTLARA 437
Query: 415 VAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGI 474
V V QE ++F+ S+ +N+ AKP+AT EE+E+AA+ A+IH+ I +LP GYDT+VGE+G
Sbjct: 438 VGVVSQETYLFHASVADNLRFAKPDATDEEIEKAARAAQIHEHIVTLPDGYDTLVGERGY 497
Query: 475 TLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRL 534
SGG++QR+A+AR +L +P +++LD+ S LD TE + + + + + +T + ++ RL
Sbjct: 498 RFSGGEKQRLAIARTILRDPPVLVLDEATSALDTRTEHAVQQAIDSLSEGRTTITIAHRL 557
Query: 535 SLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGG 575
S V+ D+++V+ G+I E G EELI + G ++ +++ G
Sbjct: 558 STVRDADQIVVLDAGRIAERGTHEELIDRDGRYAALVRRDG 598
>pir||T32865 hypothetical protein ZK484.2 - Caenorhabditis elegans
>gi|2746911|gb|AAB95060.1| (AF040659) similar to the
ATP-binding transport protein family [Caenorhabditis
elegans]
Length = 811
Score = 283 bits (716), Expect = 4e-75
Identities = 172/580 (29%), Positives = 310/580 (52%), Gaps = 15/580 (2%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAI-----DKGVSTGAY 56
R++ L RLL Y+ ++ + F + S + +P + DK +
Sbjct: 181 RETFQLLFRLLGYMGRQWKYYGMAFFFLFCYSLSRVFIPYYTGEVVTAVFGDKASYEKLH 240
Query: 57 KVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
K G+L L V G+ + Y + +R D FR++ + E+ FFD +
Sbjct: 241 KTVFIMGMLSLASTVFGGLRGGSFTYAHATIDRQ----IRNDLFRSVVKQEIGFFDMNKT 296
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGL 176
G++ SR++ D + ++ LS + +L ++ ++ SL +M ++ L+M+ LI I I+ +
Sbjct: 297 GEICSRLSADCQTMSNTLSLYMNVLTRNLTMLFGSLIFMFTLSWKLSMITLINIPIIFLV 356
Query: 177 NTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQE-NEELYSL 235
N + + + ++ ++ +A ++ I+T+KS + E ++F N L
Sbjct: 357 NKIFGVWYDMLSEETQNSVAKANDVAEEVLSSIRTVKSFACENYESSRFMTFLNVTLKIA 416
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
K + L + L +G+ ++ + +YGG +I+N + G LV+FL Y + LR
Sbjct: 417 TRKVFVVIGLIWSNELLQMGI-LTIVLWYGGHLVIENKVESGLLVSFLLYQFQLGENLRE 475
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRT 353
LG + +++ A+ ++F+ ID P+ ++ G+IEFR V +Y
Sbjct: 476 LGEVWNGLMQAVGASRKVFEFIDRPPR-VENTGTYAPDGMTGKIEFRHVAFSYPIRPDLP 534
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
+++ ++F V+PGE V + GP G GKSS + ++ FY+PT GEVLIDGV V + + L
Sbjct: 535 IMEDLTFTVEPGEVVALVGPSGGGKSSCIAMLEHFYEPTSGEVLIDGVPVREYDHKFLHT 594
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIAS-LPKGYDTVVGEK 472
VA V QEP ++ RS+ ENI + V+ +AK+A H FI + GY+T VGEK
Sbjct: 595 KVALVGQEPVLYARSVTENIGYGLDKYDDDMVQNSAKLANAHTFIMNDTTDGYNTNVGEK 654
Query: 473 GITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQ 532
G +SGGQ+QRIA+ARA++ P ++LLD+ S LDAE+E + E + + L+ KT ++++
Sbjct: 655 GSQMSGGQKQRIAIARALVRQPVVLLLDEATSALDAESEHTVQEAISKNLKGKTVILIAH 714
Query: 533 RLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
RLS V+ D+++V+ GK+ + G + L+++ G++ ++++
Sbjct: 715 RLSTVENADKIVVINKGKVEQLGNHKTLMEQEGLYKQLVQ 754
>sp|P77265|MDLA_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLA
>gi|7445960|pir||H64774 ABC-type transport protein mdlA
- Escherichia coli >gi|1773132|gb|AAB40204.1| (U82664)
multidrug resistance-like ATP-binding protein Mdl
[Escherichia coli] >gi|1786653|gb|AAC73551.1| (AE000151)
ATP-binding component of a transport system [Escherichia
coli K12]
Length = 590
Score = 282 bits (714), Expect = 7e-75
Identities = 168/569 (29%), Positives = 315/569 (54%), Gaps = 19/569 (3%)
Query: 14 YLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVA--IRYGLLILLVGV 71
Y R +L + L+++++ + P ++ +D GV+ + + + ++L+ V
Sbjct: 10 YFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD-GVTEQHFTTGQILMWIATMVLIAV 68
Query: 72 LNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERIT 131
+ + R LL A+ LR D +R + R EF+ + +G L++R TND +R+
Sbjct: 69 VVYLLRYVWRVLLFGASYQLAVELREDYYRQLSRQHPEFYLRHRTGDLMARATNDVDRVV 128
Query: 132 RFLSFRVRMLLYSIFL---IIISLYYMVRMNITL-TMVALITIAIVVGLNTTYAMKVRPI 187
V L+ S+ + ++I + + +TL +++ + +AI++ N +
Sbjct: 129 FAAGEGVLTLVDSLVMGCAVLIMMSTQISWQLTLFSLLPMPVMAIMIKRNGD------AL 182
Query: 188 YDKIRHQTGVIASIATGT---IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
+++ + +S+ T + I+ IK+ +E+ F+ + E+ N++ +I A
Sbjct: 183 HERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDRQSALFAADAEDTGKKNMRVARIDA 242
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
+ ++ +G+A G ++Q +LT+G+L +F+ Y+ M+WP+ AL + ++
Sbjct: 243 RFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQLTSFMMYLGLMIWPMLALAWMFNIVE 302
Query: 305 RSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY-HTGRTVLKGVSFKVK 363
R AA SR+ ++ AP D + V RGE++ TY T L+ V+F +K
Sbjct: 303 RGSAAYSRIRAMLAEAPVVNDGSEPVP--EGRGELDVNIHQFTYPQTDHPALENVNFALK 360
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PG+ + I GP GSGKS++L LI R + ++G++ + + K++ ++ R +A V Q PF
Sbjct: 361 PGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTPF 420
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+F+ ++ NIAL PNATQ+E+E A++A +HD I LP+GYDT VGE+G+ LSGGQ+QR
Sbjct: 421 LFSDTVANNIALGCPNATQQEIEHVARLASVHDDILRLPQGYDTEVGERGVMLSGGQKQR 480
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
I++ARA+L+N +I++LDD +S +D TE +++ +L++ Q +T +I + RLS + +
Sbjct: 481 ISIARALLVNAEILILDDALSAVDGRTEHQILHNLRQWGQGRTVIISAHRLSALTEASEI 540
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
IVM+ G I + G + L ++ G + +M +
Sbjct: 541 IVMQHGHIAQRGNHDVLAQQSGWYRDMYR 569
>sp|Q11047|YC72_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN RV1272C
>gi|7445796|pir||H70754 probable abc transporter -
Mycobacterium tuberculosis (strain H37RV)
>gi|1480314|emb|CAB00908.1| (Z77137) hypothetical
protein Rv1272c [Mycobacterium tuberculosis]
Length = 631
Score = 279 bits (706), Expect = 6e-74
Identities = 155/525 (29%), Positives = 281/525 (53%), Gaps = 5/525 (0%)
Query: 49 KGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEM 108
+GV A + + L + L L A LL Q + LR D + R +
Sbjct: 112 QGVDFAAVERTLALALALYLAAAL---MIWAQARLLNLTVQKTMVRLRTDVEDKVHRLPL 168
Query: 109 EFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALI 168
+FD G+L+SR+TND + + LS + L+ SI ++ L MV ++ L ++ L+
Sbjct: 169 SYFDGQQRGELLSRVTNDIDNLQSSLSMTISQLVTSILTMVAVLAMMVSISGLLALITLL 228
Query: 169 TIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQE 228
T+ + + + + +P++ TG + + T +G +K+ + + +F +
Sbjct: 229 TVPLSLLVTRAITRRSQPLFVAHWTSTGRLNAHLEETYSGFTVVKTFGHQAAARERFHEL 288
Query: 229 NEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLT 288
N+++Y A ++ L A + L + GG + +T+G + AF+ Y+
Sbjct: 289 NDDVYQAGFGAQFLSGLVQPATAFIGNLGYVAVAVAGGLQVATGQITLGSIQAFIQYIRQ 348
Query: 289 MMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY 348
PL L +Q +A+A R+FDV+D +S +P E+ N G +EF V Y
Sbjct: 349 FNMPLSQLAGMYNALQSGVASAERVFDVLDEPEESPEPEP--ELPNLTGRVEFEHVNFAY 406
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
G V++ +S +PG V I GP G+GK++++ L+ RFY+ G +LIDGV++A +
Sbjct: 407 LPGTPVIRDLSLVAEPGSTVAIVGPTGAGKTTLVNLLMRFYEIGSGRILIDGVDIASVSR 466
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTV 468
++LR + V Q+ ++++ +I ENIA +P AT +E+ AA+ A + F+ +LP GY T
Sbjct: 467 QSLRSRIGMVLQDTWLYDGTIAENIAYGRPEATTDEIVEAARAAHVDRFVNTLPAGYQTR 526
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
V G ++S G++Q I +ARA L P++++LD+ S++D TE + ++E+ +D+T+
Sbjct: 527 VSGDGGSISVGEKQLITIARAFLARPQLLILDEATSSVDTRTELLIQRAMRELRRDRTSF 586
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
I++ RLS ++ D ++V++ G+IVE G EL+ + G++ +M +A
Sbjct: 587 IIAHRLSTIRDADHILVVQTGQIVERGNHAELLARRGVYYQMTRA 631
>pir||S58356 pepT protein - Staphylococcus epidermidis >gi|2126599|pir||S66651
pepT protein - Staphylococcus epidermidis
>gi|945015|emb|CAA90021.1| (Z49865) PepT [Staphylococcus
epidermidis]
Length = 571
Score = 279 bits (706), Expect = 6e-74
Identities = 183/570 (32%), Positives = 307/570 (53%), Gaps = 25/570 (4%)
Query: 3 KSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY 62
K N L L S ++ F+I + + + S T IVP+L N ID V + +++
Sbjct: 2 KKENPLFFLFSKIKWPKSLFIIAIIISSIGSITEIIVPLLTGNLIDLLVKQ---TLELKF 58
Query: 63 GLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISR 122
+ ++L+ +L+ +FS G +LL+K + +Y +R ++ I FFDK SGQLISR
Sbjct: 59 IVFLILMFLLDAIFSGLGLFLLIKVGEKIIYSIRSILWKHILFLNTSFFDKNESGQLISR 118
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
IT+DT I F+S ++ ++ S +I S+ + M+ +T++ I I I + M
Sbjct: 119 ITDDTSLINNFISQKLPAIIPSFITLIGSITMLFIMDWKMTLLTFIIIPI-------FLM 171
Query: 183 KVRP---IYDKIRHQTGVIASIATGTIAG-IKTIKSLSVEENVQTKFSQENEEL---YSL 235
+ P I +K+ +T + TGTI I I+ + + N + + + E+L Y L
Sbjct: 172 VIIPLGNIIEKLSFKTQQKVADFTGTIGRVISAIRLVKISTNEEFELNNTKEKLSSIYKL 231
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
N+K KI A+ ++L + + + YGG I +T G LV+ + Y++ + P+
Sbjct: 232 NIKHAKIIAILQPFTSILLLVMIGIILSYGGYRIAVGAITSGTLVSMIFYVIQLSSPISE 291
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISN--PRGEIEFRDVWLTYHTGRT 353
+ I + + S A+ R++ +++ + + V + N E+ F V+ +Y + +
Sbjct: 292 ISTLITEYKSSKGASKRIYGILNEPVEE----NKVNLENIPQNKELIFNSVYFSYDS-KN 346
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VL+ VSF V +K I GP GSGKS+IL LI+R YK G + G ++ I + R
Sbjct: 347 VLENVSFAVPINKKTAIVGPSGSGKSTILNLISRLYKADSGGIYYGGHSIYDIDLKKWRI 406
Query: 414 IVAYVPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEK 472
+ YV Q + N SIR+NI N + +E+E + +A HDFI++LP YD+ +GE
Sbjct: 407 KLGYVMQNNIMMNGSIRDNILYGVSNNISDDELEYYSILANSHDFISNLPHQYDSQIGES 466
Query: 473 GITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQ 532
GI LSGGQ+QRI +AR ++ NP I+LLD+ ++LD+E+EKK+ L + Q++T +I+
Sbjct: 467 GIKLSGGQKQRINIARNLIKNPDILLLDEATASLDSESEKKIQNALNNLFQNRTTIIIGI 526
Query: 533 RLSLVKLVDRVIVMKDGKIVEDGKPEELIK 562
L++ D++I + +GKI G LIK
Sbjct: 527 AYRLLRTADQIIFLDNGKITGIGTHHYLIK 556
>emb|CAB88985.1| (AL353864) putative ABC-transport protein. [Streptomyces coelicolor
A3(2)]
Length = 624
Score = 279 bits (706), Expect = 6e-74
Identities = 169/582 (29%), Positives = 300/582 (51%), Gaps = 21/582 (3%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
R+ ++ R H + + L + + PVL +D VS G +R LLI L+
Sbjct: 29 RIGAFARPHRRRIVRFVLLGVATALLAVATPVLAGKVVDAIVSDGDEGTVVRLALLIALI 88
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
V V + R L + + LR F +QR + FF +T +G L+SR+ ND
Sbjct: 89 AVAEAVLGIFSRRLSATLGEGLILDLRTAVFDHVQRMPVAFFTRTRTGALVSRLNNDVIG 148
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
R S + ++ ++ ++++L M+ ++ +T++AL+ + + V ++ +
Sbjct: 149 AQRAFSNTLSGVVSNVVTLLLTLAVMLTLSWQITLLALVLLPVFVLPARRMGRRMARMQR 208
Query: 190 KIRHQTGVIASIATGTIA--GIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYG 247
+ + + T + G IK E +F+ + + V+ A +
Sbjct: 209 EAAALNAAMGTRMTERFSAPGATLIKLFGRPEEESAEFADRARRVADIGVRTATAQAAFI 268
Query: 248 NAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL 307
A LV LA++ ++ GG ++ TL G +VA + + PL AL ++ +L
Sbjct: 269 TALTLVSALALALVYGLGGFFALRGTLDAGAVVALALLLTRLYAPLTALAGARVEVMSAL 328
Query: 308 AAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT----------------- 350
+ R+F+V+D AP + PDA + + +EF DV Y +
Sbjct: 329 VSFERVFEVLDLAPLIDEKPDARPVPDGPVAVEFDDVRFGYPSADKVSLASLEEVATLDT 388
Query: 351 --GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
G VL G+SF+ +PG+ + + G G+GKS+I +L+ R Y G V + GV+V ++
Sbjct: 389 RGGEEVLHGLSFRAEPGQTIALVGSSGAGKSTIAQLLPRLYDTDGGTVRVGGVDVRELSA 448
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTV 468
+LR V V Q+ +F+ ++R N+ LA+P+AT++++ A + A++ D + SLP G DTV
Sbjct: 449 RSLRDTVGMVTQDGHLFHDTVRANLLLARPDATEDDLWEALRRARLADLVRSLPDGLDTV 508
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
VGE+G LSGG+RQR+ +AR +L ++V+LD+ ++LD +E + E L E LQ +TA+
Sbjct: 509 VGERGYRLSGGERQRMTIARLLLARQRVVILDEATAHLDNTSEAAVQEALTEALQGRTAV 568
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+++ RLS V+ DR++V++ G+IVE G EEL+ G ++++
Sbjct: 569 VIAHRLSTVRAADRILVVEAGRIVESGTHEELLAVDGRYAQL 610
>emb|CAB76004.1| (AL157916) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 627
Score = 278 bits (703), Expect = 1e-73
Identities = 180/575 (31%), Positives = 296/575 (51%), Gaps = 16/575 (2%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVST---GAYKVAIRYGLLIL 67
L S L + + L++L P+L+ AID V + I G L
Sbjct: 51 LRSLLMPMKARVALTVLLLLLQQAAVQAGPLLVAYAIDHAVPALRDDDHGPLIAVGAGYL 110
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
L + G A + +Q + LR FR Q ++F ++ SG+LISR T D
Sbjct: 111 LCSLAAGGLQYAFIAAAARVSQDVLLDLRGRIFRHAQALSVDFHERYTSGRLISRSTTDV 170
Query: 128 ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
E + L ++ L+ I + ++ +++ L VA+ + + L Y + +
Sbjct: 171 ESLRELLDEGLQELVTVILSFVYIAALLLWLDLGLGAVAVASFVPLYALVRLYQRRAGRV 230
Query: 188 YDKIRHQTGVIASIATG---TIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
Y R ++ IA++ T+ GI+ ++S E F+ N N A+ A
Sbjct: 231 Y---RQRSTAIAAVIVKFVETMNGIRPVRSFRREAANDADFAVLNHRHERTNGDALLEMA 287
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
Y LV A++ + +G + TL +G L A + Y+ + P+ LG + Q
Sbjct: 288 RYVVGSRLVANTAVAGIVLWGAYRVADGTLALGVLAAAVLYLRRLYDPIDRLGMFLNSYQ 347
Query: 305 RSLAAASRLFDVIDSAPKSIDPPDA------VEISNPRGEIEFRDVWLTYHTGRTVLKGV 358
+ A+ ++ ++ P S+ P A +E +P E+ F V Y TG VL
Sbjct: 348 SAAASLEKIAGLLAQTP-SVPEPTAPKELPPLESEHPGREVVFDSVSFGYRTGGEVLPRF 406
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
+ G+ V + G G+GKS++ KL+ARFY P+ G VL+DG ++ + LR+ V V
Sbjct: 407 GLTLPAGQTVAVVGSTGAGKSTLAKLLARFYDPSAGRVLLDGTDLRDLAVPELRRGVVMV 466
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
QE F+F+ ++ +NIA+ +P AT+EE+ERAAK HDFIA+LP GYDT V ++G +S
Sbjct: 467 TQEAFLFSGTVADNIAIGRPEATREEIERAAKAIGAHDFIAALPDGYDTDVRKRGGRISA 526
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
GQRQ +A ARA+L +P +++LD+ S+LD E+ + + +L+ +TA++++ RLS V+
Sbjct: 527 GQRQLVAFARALLADPAVLILDEATSSLDIPGERAVQRAMTTVLKGRTAVVIAHRLSTVE 586
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ DRV+VM+ G+IVEDG P+ELI G F+++ +A
Sbjct: 587 IADRVLVMEHGRIVEDGAPDELIAGTGRFADLHRA 621
>emb|CAC13096.1| (AL445503) putative ABC transporter ATP-binding protein
[Streptomyces coelicolor A3(2)]
Length = 600
Score = 277 bits (701), Expect = 2e-73
Identities = 166/576 (28%), Positives = 309/576 (52%), Gaps = 10/576 (1%)
Query: 3 KSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY 62
+ + ++++L RG ++GL L+ S + P L++ +D + G +
Sbjct: 20 RQVRRILKLFRPYRGRLA--VVGL-LVGAASLVSVATPFLLKEILDVAIPEGRTGLLSLL 76
Query: 63 GLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISR 122
L ++ VL VF + + Q ++ LR + +Q+ + FF +T +G++ SR
Sbjct: 77 ALGMIFGAVLTSVFGVLQTLISTTVGQRVMHDLRTAVYGRLQQMSLAFFTRTRTGEVQSR 136
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
I ND + ++ L+ ++ ++ ++ MV ++ LT+V+L+ + + V ++
Sbjct: 137 IANDIGGMQATVTSTATSLVSNLTSVVATIVAMVVLDWRLTVVSLLLLPVFVWISRRVGR 196
Query: 183 KVRPIYDKIRHQTGVIASIATGT--IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
+ R I + + Q +A+ T + ++GI +++ +++ F+ E+E L L V++
Sbjct: 197 ERRKITTRRQKQMAAMAATVTESLSVSGILLGRTMGRSDSLTRAFADESESLVDLEVRS- 255
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQ---NTLTVGELVAFLTYMLTMMWPLRALG 297
+ + A ++ AM + Y+ +Q +++G +VAF++ + P +L
Sbjct: 256 NMAGRWRMAVITIVMAAMPAVIYWTAGIALQLGGPDVSLGTIVAFVSLQQGLFRPTVSLL 315
Query: 298 FTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH-TGRTVLK 356
T IQ SLA R+F+ +D + DAV + + +GE+ F V Y G VL
Sbjct: 316 STGVQIQSSLALFQRIFEYLDLPIDITERKDAVHLDHIKGEVRFEGVGFGYGGKGGPVLD 375
Query: 357 GVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVA 416
G+ V G + + GP G+GKS++ L+ R Y T G V +DGV+V + + L + V
Sbjct: 376 GIDVTVPAGSSLAVVGPTGAGKSTLGHLVPRLYDVTDGRVTLDGVDVRDLDFDTLARAVG 435
Query: 417 YVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
V QE ++F+ S+ EN+ AKP+AT E+E AA+ A+IHD IA+LP GYDTVVGE+G
Sbjct: 436 VVSQETYLFHASVAENLRFAKPDATDAELEAAARAAQIHDHIAALPDGYDTVVGERGHRF 495
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSL 536
SGG++QR+A+AR +L +P +++LD+ S LD TE + + + ++T + ++ RLS
Sbjct: 496 SGGEKQRLAIARTILRDPPVLVLDEATSALDTRTEAAVQGAIDALSANRTTITIAHRLST 555
Query: 537 VKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
V+ DR++V+ G++ E G E L+ + G ++ +++
Sbjct: 556 VRDADRIVVLDSGRLAEQGTHEALLAQDGRYAALVR 591
>sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN 1 IN GLVBC
3'REGION >gi|7445716|pir||E69802 ABC transporter
(ATP-binding protein) homolog yfiB - Bacillus subtilis
>gi|1486244|dbj|BAA09106.1| (D50543) unknown [Bacillus
subtilis] >gi|2633145|emb|CAB12650.1| (Z99108) similar
to ABC transporter (ATP-binding protein) [Bacillus
subtilis]
Length = 573
Score = 277 bits (700), Expect = 3e-73
Identities = 169/566 (29%), Positives = 296/566 (51%), Gaps = 7/566 (1%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
+ LS+L+ +++ I L L++ + P+LI ID G+ + +G +++ +
Sbjct: 3 KALSFLKPYSLLAGIALILMLTELAVELMQPLLIAKIIDDGILKQDLRHVWIWGTVMIGL 62
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
VL+ + + +Q Y R F+ IQ F + S I+R+TND +
Sbjct: 63 TVLSFAAGMLNSFYAAHVSQSFSYDTRKGLFQKIQSFSYSTFGQFSSSSYITRLTNDVTQ 122
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ + +R +L + +I + + +N+ L L+TI I++ K ++
Sbjct: 123 VQNMIFMSLRFMLRAPLMIAGGIVLSLAVNVKLGFFLLVTIPILILFLLWVLRKGGALFR 182
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
++ + + +I + IK IK+L + +F + N L V A ++
Sbjct: 183 SVQKRLDQVNTIMQENLIAIKLIKALLRGSHEVKRFIKANTRLMEKTVSAFQLVEFTMPV 242
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
L++ L + + + G +I + VG++VA + Y + L F I R+ A+
Sbjct: 243 LMLLMNLCILLILWAGSYSITSGSTQVGDVVAIINYATRITGALSMFPFLIMIFTRAKAS 302
Query: 310 ASRLFDVIDSAPKSIDPPDAVEISNP-RGEIEFRDVWLTY-HTGRTVLKGVSFKVKPGEK 367
R+ +V+++ D + IS+ G IEF+ V Y R L+ VSF KP E
Sbjct: 303 GDRIGEVLETEG---DEREEGTISDRLSGRIEFQHVSFRYPEMDREALRNVSFSAKPRET 359
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
+ I G GSGKS++ +LI R Y+P G + ID V I E LR+ + YVPQE +F+
Sbjct: 360 IAILGATGSGKSTLFQLIPRLYQPDSGRIYIDEKPVQDIPAEGLRRQIGYVPQEVLLFSG 419
Query: 428 SIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALA 487
+I+ENIA K NA+ +E+ AAK+A+IH+ I LP GYDTV+G++G+ LSGGQ+QRI++A
Sbjct: 420 TIKENIAWGKENASLDEIMDAAKLAQIHETILKLPNGYDTVLGQRGVNLSGGQKQRISIA 479
Query: 488 RAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMK 547
RA++ P I+LLDD S LD +TE KL+E + T LI++Q+++ D++++++
Sbjct: 480 RALIRKPAILLLDDSTSALDLQTEAKLLEAIS--TYHCTTLIITQKITTAMKADQILLLE 537
Query: 548 DGKIVEDGKPEELIKKGGIFSEMMKA 573
DG+++E G EL+ + ++ + ++
Sbjct: 538 DGELIEKGTHSELLSESQLYKRIYES 563
>gb|AAF48177.1| (AE003489) CG1824 gene product [Drosophila melanogaster]
Length = 761
Score = 277 bits (700), Expect = 3e-73
Identities = 177/556 (31%), Positives = 292/556 (51%), Gaps = 16/556 (2%)
Query: 23 LIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRY 82
L+G + L Y N+ V I N+ K VS A + Y +L F+ Y
Sbjct: 153 LLGDLVNTLARYANTYVMDPINNSFVKDVSKPASNLLSLY--------MLQSGFTFMYIY 204
Query: 83 LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLL 142
LL + + +R D F I ++ FFD+ +G+L++R+T D + V L
Sbjct: 205 LLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGL 264
Query: 143 YSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIA 202
S +I + ++ + +AL ++ VV T K+R + + Q +
Sbjct: 265 RSAAQLIGGSISLFMISPHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVC 324
Query: 203 TGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK-AMKITALYGNAPFLVLGLAMSTM 261
++ I+T++S + E F E E L K I G F + L +ST+
Sbjct: 325 EEALSNIRTVRSSACEYREMQLFEAETNEAARLAQKLGYGIAIFQGLTNFFLNTLVLSTL 384
Query: 262 FYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP 321
F GG + +L+ G L+AFL + L +G + R ++A SR+F+ + P
Sbjct: 385 FM-GGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAGSRVFEFLSLQP 443
Query: 322 KSIDPPDAVEISNPR--GEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLITGPPGSG 377
+ ++ I R GEI F +V Y VLK S ++PG+ V + G GSG
Sbjct: 444 Q-VELLRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSG 502
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK-IVAYVPQEPFIFNRSIRENIALA 436
KS+I L+ RFY+P+ G + +DG ++ I LR ++ ++ Q+P +F SI ENI
Sbjct: 503 KSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYG 562
Query: 437 KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKI 496
KP+A +E+V AA++++ HDF+ +LP GY T VGE+G LSGGQRQRIA+ARA+L NP+I
Sbjct: 563 KPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRI 622
Query: 497 VLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGK 556
++LD+ S LDA +E ++ + L ++Q++T L+++ RLS ++ D ++V+ G++VE GK
Sbjct: 623 LILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGK 682
Query: 557 PEELIKKGGIFSEMMK 572
+EL+ K G++ E+++
Sbjct: 683 HDELMGKRGLYFELVR 698
>sp|P45861|YWJA_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN IN ACDA 5'REGION
>gi|1075816|pir||S55415 ATP-binding transport protein
ywjA - Bacillus subtilis >gi|853754|emb|CAA89862.1|
(Z49782) ABC transporter [Bacillus subtilis]
>gi|2636260|emb|CAB15751.1| (Z99123) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 575
Score = 273 bits (692), Expect = 3e-72
Identities = 151/546 (27%), Positives = 289/546 (52%), Gaps = 17/546 (3%)
Query: 45 NAIDKGVSTGAYKVAIRYGLLILLVG-----VLNGVFSLAGRYLLVKAAQYAVYY----- 94
+AI G+ ++ + + Y + LL G ++ L Y L A QY V Y
Sbjct: 22 SAIAGGLMELSFPLIVNYFIDTLLPGRDWGLIIATSIGLFAVYALSSALQYIVTYWGHML 81
Query: 95 -------LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFL 147
+R F +Q+ +F+D +G L+S++TND I L ++
Sbjct: 82 GINIETDMRKSLFDHLQKLSFKFYDNNKTGTLMSKLTNDLMYIGEVAHHGPEDLFIAVMT 141
Query: 148 IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIA 207
I+ + M+ +N L ++ I + IV+ L + K+ + + G ++ I
Sbjct: 142 ILGAFGVMLFINWQLALLTFIIMPIVIWLALYFNKKMTKAFTTLNKDIGDFSARVENNIG 201
Query: 208 GIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGK 267
GI+ +++ E + +F+ N+ + + KI A G+ +++ + G
Sbjct: 202 GIRLVQAFGNEAFEKERFAVNNQRFRVTKLSSYKIMAKNGSISYMLTRFVTLFVLLCGTW 261
Query: 268 AIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPP 327
+I+ +L+ GE VAF+ + P+ + I R +A +++++ P D P
Sbjct: 262 FVIRGSLSYGEFVAFVLLTNVLFRPIDKINAIIEMYPRGIAGFKSYMELMETEPDIQDSP 321
Query: 328 DAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIAR 387
D+ ++S +G I ++ V Y VL ++ ++ GE V GP G+GKS++ L+ R
Sbjct: 322 DSKDVSGLKGNIRYKHVSFGYDDHHNVLNDINLSIQAGETVAFVGPSGAGKSTLCSLLPR 381
Query: 388 FYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVER 447
FY+ ++G++ IDG+++ + +LR + V Q+ F+F+ ++RENIA + A++E++ +
Sbjct: 382 FYEASEGDITIDGISIKDMTLSSLRGQIGVVQQDVFLFSGTLRENIAYGRLGASEEDIWQ 441
Query: 448 AAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLD 507
A K A + + + ++P G DT++GE+G+ LSGGQ+QR+++AR L NP I++LD+ S LD
Sbjct: 442 AVKQAHLEELVHNMPDGLDTMIGERGVKLSGGQKQRLSIARMFLKNPSILILDEATSALD 501
Query: 508 AETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIF 567
ETE + + L+E+ + +T L+++ RL+ +K DR++V+ + I E G+ ++LI+ GG++
Sbjct: 502 TETEAAIQKALQELSEGRTTLVIAHRLATIKDADRIVVVTNNGIEEQGRHQDLIEAGGLY 561
Query: 568 SEMMKA 573
S + +A
Sbjct: 562 SRLHQA 567
>pir||A75554 ABC transporter, ATP-binding protein, MsbA family - Deinococcus
radiodurans (strain R1)
>gi|6457828|gb|AAF09749.1|AE001878_8 (AE001878) ABC
transporter, ATP-binding protein, MsbA family
[Deinococcus radiodurans]
Length = 606
Score = 273 bits (692), Expect = 3e-72
Identities = 172/557 (30%), Positives = 290/557 (51%), Gaps = 16/557 (2%)
Query: 28 LIILMSYTNSIVPVLIR-NAIDKGVSTGAYKVAIRYGLLILLVGV--LNGVFSLAGRYLL 84
L++L S + P L+ +D+G+ + + G L +LVGV L V S LL
Sbjct: 29 LLLLGSVAAELYPPLVWIRVVDQGIPARDW--GLIGGQLAVLVGVFALQQVLSAWRGVLL 86
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYS 144
+A Q LR +R +Q ++F+ +G L+ R+T D + + L ++ +
Sbjct: 87 ERAGQQFTLDLRTAVYRKLQSQSADYFETQRTGDLLVRVTGDVDALQDVLVRGTDSVIAN 146
Query: 145 IFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATG 204
++ + + + L ++ + + V L Y VRP Y R + G ++++
Sbjct: 147 ALRLVGVIGIFIALQPLLGVLTTLPMLAVGLLLWNYGKTVRPAYRAARARLGELSALIAD 206
Query: 205 TIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYY 264
+AGI+ ++ + EE + ELY +A+ + V L M
Sbjct: 207 RLAGIRVVQGFAREEAEAARVEALGRELYREQARAVALRNRAFPVARFVGNLGNVIMLGG 266
Query: 265 GGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSI 324
G I+ T+G L+A+ Y P+ L +QR+ AA R+F V+D+
Sbjct: 267 GAWLILAGQFTLGGLLAYRGYGRYFYGPIDDLVNISDLLQRAEAAGRRVFAVLDAPVTVA 326
Query: 325 DPPDAVEISNP-RGEIEFRDVWLTYHTG----------RTVLKGVSFKVKPGEKVLITGP 373
DP + P RGE+ F +V Y + + +L+GV+ + G++V + G
Sbjct: 327 DPAHPKPLPTPVRGELHFDNVTFGYDSASYDSASSDPTQPILRGVTLHIPAGQRVALLGA 386
Query: 374 PGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENI 433
G+GKS++L L+ R + P G VL+DGV+V + LR A +PQ+ F+F+ ++ EN+
Sbjct: 387 SGAGKSTLLGLVTRQHDPQSGRVLLDGVDVRDVALAELRTAAAVMPQDTFLFHDTVLENV 446
Query: 434 ALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMN 493
A+P+A EVE A + A DF+ +LP+G +T+VGE+G+ LSGGQRQR+A+AR +L
Sbjct: 447 RYARPDAALAEVEEALRAAYALDFVRALPQGLETLVGERGVRLSGGQRQRLAIARTLLAR 506
Query: 494 PKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVE 553
P ++LLD+P S +DAE+E ++V L +++Q +T+L V+ RLSL + DRV+V+ G +VE
Sbjct: 507 PALLLLDEPTSAVDAESEAQVVAALNDLMQGRTSLTVTHRLSLARAADRVLVLDGGVVVE 566
Query: 554 DGKPEELIKKGGIFSEM 570
DG P L +GG ++ +
Sbjct: 567 DGPPALLRTRGGPYARL 583
>emb|CAB05918.1| (Z83328) transport-associated protein [Salmo salar]
Length = 708
Score = 273 bits (691), Expect = 4e-72
Identities = 166/570 (29%), Positives = 307/570 (53%), Gaps = 21/570 (3%)
Query: 9 IRLLSYLRGHAVHFLIGLFLIILMSY-TNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
+R+L + R + L+G F+ + ++ + + +P ID + YK +IL
Sbjct: 135 MRVLYFYRPDTL-LLVGAFIFLALAVLSETFIPFYTGKVID--ILASQYKWNDFLTAIIL 191
Query: 68 LVGVLNGVFSLAGRY-------LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
+ G++SL + L + A ++++ F A+ + E+ FF+ +G +
Sbjct: 192 M-----GLYSLGSSFSAGCRGGLFMCAINSFTCRMKVELFGALVKQEISFFETIKTGDIT 246
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
SR++ DT ++ R L+ V +LL ++ + L M+ ++ LT++ L+ I L Y
Sbjct: 247 SRLSTDTTKMARALALNVNVLLRTLIKTVGMLSLMMSLSWKLTLLMLMETPITGLLQGVY 306
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
+ +++ A T+AGI+T++S + E + ++ + ++L +
Sbjct: 307 DNYYLRLSKEMQDSMARANEAAGETVAGIRTVRSFNTERSEAGRYDHRLMDTHNLKTRRD 366
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
+ A+Y L + M YYG I + ++ G LV+F+ Y + +R L +
Sbjct: 367 TVRAVYLLLKRLTALVMQVAMLYYGRLFIQRGQMSTGNLVSFILYQSNLGANIRTLIYIF 426
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKGV 358
GD+ S+ AA ++F+ +D P+ + ++ G + F ++ +Y T GR VL+G
Sbjct: 427 GDMLNSVGAAGKVFEYLDREPQ-VSTKGTLQPETLTGHVHFHNLSFSYPTRQGRKVLQGF 485
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
S +++PG+ + GP G GKS+ + L+ RFY+P +GE+L+DG + + L + VA V
Sbjct: 486 SLELRPGQLTALVGPSGGGKSTCVSLLERFYQPQQGEILLDGQPLHSYQHHYLHRKVAMV 545
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
QEP +F+ SI++NIA + + E V+ AA+ A H FI+ L KGYDT VGE+G +SG
Sbjct: 546 GQEPVLFSGSIKDNIAYGLADCSLERVQEAARRANAHSFISQLEKGYDTDVGERGGQMSG 605
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
G++QRIA+ARA++ P++++LD+ S LD E+E +V++ +T L+++ RL ++
Sbjct: 606 GEKQRIAIARALIREPQVLILDEVTSALDTESE-HMVQEALASCPSQTLLVIAHRLKTIE 664
Query: 539 LVDRVIVMKDGKIVEDGKPEELI-KKGGIF 567
DR+I++ G ++E G +EL+ +KGG +
Sbjct: 665 RADRIILIDRGSVLEQGTHQELMDRKGGYY 694
>dbj|BAB04876.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 583
Score = 273 bits (690), Expect = 5e-72
Identities = 155/562 (27%), Positives = 313/562 (55%), Gaps = 20/562 (3%)
Query: 22 FLIGLFLIILMSYTNSIVPVLIRNAIDK------GVSTGAYKVAIRYGLLILLVGVLNGV 75
+ I L L++++ T+ ++ AID V +G Y YG ++ L+ V++
Sbjct: 19 YTIALVLLLIVGITDLAPAWILGLAIDDFQMGQLSVQSGLY-----YGGILTLIMVISYG 73
Query: 76 FSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLS 135
+ L A LR R + + + F+++ +G L++R TND + ++
Sbjct: 74 LTFVWMSKLFGGAFVIERKLRSKFMRHLFKMDPTFYERQRTGDLMARGTNDLKAVSNTAG 133
Query: 136 FRVRMLL-YSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQ 194
F + L+ S+F+ I + V ++ LT+ A++ + ++ + T K+ + +
Sbjct: 134 FGILTLIDSSVFMFTILIAMCVLIDWKLTIAAVLPLPLMAIIITVLGKKIHGRFMMAQDA 193
Query: 195 TGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVL 254
G + ++ G++ I++ S E + F + +E +Y N+ K AL+ A +++
Sbjct: 194 FGSLNDKVLESVGGLRVIRAFSKERADEDHFREMSENVYQKNILVAKTDALFEPAVNIIV 253
Query: 255 GLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLF 314
G++ +G + Q +T+G+LV F Y+ ++WP+ A+G I +QR A+ R+
Sbjct: 254 GMSYIIGLGFGSYLVFQQQITLGQLVTFNVYLGMLIWPMFAIGELINIMQRGSASLDRID 313
Query: 315 DVI---DSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGR-TVLKGVSFKVKPGEKVLI 370
+ + + P P + + +I F+ + Y + T LK VSF+V GE + I
Sbjct: 314 ETLREREDVPNPEQPTNTTDFQ----DIRFQQLSFKYPGSKGTQLKQVSFQVNRGETLGI 369
Query: 371 TGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIR 430
G GSGK++++K + ++Y +GEV + + ++ +++RK + YVPQ+ +F+++++
Sbjct: 370 VGRTGSGKTTLVKQLLKYYPIHEGEVSLTDTALRDMEKQHVRKWIGYVPQDHILFSKTVK 429
Query: 431 ENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAM 490
ENI K +A +EE+++A +++ ++ LP G +T+VGEKG+ LSGGQ+QRI++ARA+
Sbjct: 430 ENILFGKQDAMEEELQKAIRLSAFDQDLSFLPDGLETLVGEKGVALSGGQKQRISIARAL 489
Query: 491 LMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGK 550
+ +P I++LDD +S +DA+TE K++ ++++ KT +I + R+S V+ DR++V+ +G+
Sbjct: 490 IADPDILILDDSLSAVDAKTEAKIIGNIRKERAGKTTVITTHRISAVEHADRILVLDEGR 549
Query: 551 IVEDGKPEELIKKGGIFSEMMK 572
++E+G ++L++K G ++E +
Sbjct: 550 VIEEGTHQQLLQKDGWYAEQAR 571
>dbj|BAA92038.1| (AK002018) unnamed protein product [Homo sapiens]
Length = 735
Score = 272 bits (689), Expect = 6e-72
Identities = 155/512 (30%), Positives = 275/512 (53%), Gaps = 5/512 (0%)
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
L++L GV G+ + LL + +R F ++ R ++ FFD +GQL+SR+T
Sbjct: 198 LLILYGV-QGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLT 256
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
D + + L S + L + ++ LT++ ++ ++G+ T +
Sbjct: 257 TDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGL 316
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
R + + + Q +A + ++T+++ ++E+ + ++ E E + + + A
Sbjct: 317 RKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACHCRAEELGRGIA 376
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
L+ + + + GG + LT G+L++FL T+ + L G +
Sbjct: 377 LFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVV 436
Query: 305 RSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFK 361
R L+A +R+F+ + P + V RG + F++V +Y G VLK +
Sbjct: 437 RGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLT 496
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR-KIVAYVPQ 420
+ PG+ V + G G GK+++ L+ RFY PT G V++DG ++ + LR ++V ++ Q
Sbjct: 497 LPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQ 556
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
EP +F +I ENI K A+ EEV AA+ A H+FI S P+GY+TVVGE+G TLSGGQ
Sbjct: 557 EPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQ 616
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
+QR+A+ARA++ P +++LD+ S LDAE+E+ + E L +T L+++ RLS V+
Sbjct: 617 KQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGA 676
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
++VM DG++ E G EEL+KKGG+++E+++
Sbjct: 677 HCIVVMADGRVWEAGTHEELLKKGGLYAELIR 708
>gb|AAG25076.1|AF273216_1 (AF273216) ABC transporter RzcB [Rhizobium leguminosarum bv.
viciae]
Length = 735
Score = 272 bits (688), Expect = 8e-72
Identities = 175/562 (31%), Positives = 309/562 (54%), Gaps = 26/562 (4%)
Query: 21 HFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLN-GVFSLA 79
H LI +I + + + P+ + +DK ++ +Y L++L+VG+ G+F +
Sbjct: 178 HVLIASLVIQIFAL---VTPLFFQVVVDKVLAHRSYST-----LIVLVVGLAAVGLFDVV 229
Query: 80 GRYLLVKAAQYAVYYLRMDAFRAIQRH----EMEFFDKTFSGQLISRITNDTERITRFLS 135
+YL A + + ++ R + RH + +F+ +GQ ++RI + E I FL+
Sbjct: 230 LQYLRTYALSHTTNRIDVELGRRLFRHLLNLPLSYFETRATGQTVARI-RELETIRNFLT 288
Query: 136 ----FRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKI 191
F L+++I I + Y ++ +VA I + +G +K R D+
Sbjct: 289 GQGLFSGLDLIFTIIFIFVLFSYSSKL--AWIVVASIPFYMAIGFLIRPFLKER--IDEK 344
Query: 192 RHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPF 251
+ + T+ GI+T+K+ +VE V +++ + + A + A NA
Sbjct: 345 FERGAFSQQLLVETVVGIQTLKASAVEPVVSSQWEERLAAYVRSSFLATMLAAKGQNAIQ 404
Query: 252 LVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAAS 311
V + + + +G +A+I L+VG LVAF + P+ L D Q+ + +
Sbjct: 405 YVNKITSAALLLFGAQAVIDGELSVGALVAFNMIAGQVSQPILRLSQLWQDFQQVQVSIA 464
Query: 312 RLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT-GRTVLKGVSFKVKPGEKVLI 370
RL D+++ AP+ P AV + P+G I F+ V Y G+ VLK ++F ++PGE + I
Sbjct: 465 RLSDILN-APQEPRPSVAVSLPPPKGAIAFKSVNFRYSPDGQDVLKDINFSIRPGEVIGI 523
Query: 371 TGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI-FNRSI 429
GP GSGKS++ KL+ RFY P G+V +DG ++A++ LR + V QE + FNR+I
Sbjct: 524 VGPSGSGKSTLTKLVQRFYIPNNGQVFVDGQDIAQVDPAWLRSNIGVVLQENMLLFNRTI 583
Query: 430 RENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARA 489
+NI + P ++ + A+++ FIA LP+GYDT++ E+G LSGGQRQR+A+ARA
Sbjct: 584 HDNICMVNPAMSRAAAIQMARLSGADQFIAKLPRGYDTLIEERGANLSGGQRQRLAIARA 643
Query: 490 MLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDG 549
+ NP I++LD+ S LD E+E+ ++ +++EI++ +T +I++ RL+ V+ +R+I MKDG
Sbjct: 644 LATNPPILILDEATSALDYESERIILGNMREIVRGRTVIIIAHRLATVRHCNRIIGMKDG 703
Query: 550 KIVEDGKPEELI-KKGGIFSEM 570
+IVE+G E L+ + G+++ +
Sbjct: 704 RIVEEGTHETLLARPNGLYAHL 725
>emb|CAB69752.1| (AL137187) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 642
Score = 271 bits (686), Expect = 1e-71
Identities = 155/526 (29%), Positives = 278/526 (52%), Gaps = 4/526 (0%)
Query: 49 KGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEM 108
+G+ GA + LL L + G+ L+ +A ++ LR D + R +
Sbjct: 110 QGIDFGAVGEVL---LLALATFAVAGLLMAVATRLVNRAVNRTMFRLREDVQTKLSRLPL 166
Query: 109 EFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALI 168
+FDK G+++SR TND + I + L + L+ S+ II L M ++ L +VAL+
Sbjct: 167 SYFDKRQRGEVLSRATNDIDNIGQTLQQSMGQLINSLLTIIGVLAMMFYVSWILALVALV 226
Query: 169 TIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQE 228
T+ + + T + +P + + TG + + G +K +E +F+++
Sbjct: 227 TVPLSFVVATRVGKRSQPQFVQQWRSTGQLNAHIEEMYTGHALVKVFGRQEESAKQFAEQ 286
Query: 229 NEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLT 288
N+ LY KA + + V L + GG + L++G++ AF+ Y
Sbjct: 287 NDALYEAGFKAQFNSGIMQPLMMCVSNLNYVLVAVVGGLRVASGQLSIGDVQAFIQYSRQ 346
Query: 289 MMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY 348
PL + +Q +A+A R+F+++D+ +S DP + RG +E V Y
Sbjct: 347 FSMPLTQVASMANLVQSGVASAERVFELLDAEEQSADPIPGARPEDLRGRVELEHVSFRY 406
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
+ +++ +S KV+PG V I GP G+GK++++ L+ RFY+ + G + +DGV++AK+
Sbjct: 407 DPEKPLIEDLSLKVEPGHTVAIVGPTGAGKTTLVNLLMRFYEVSGGRITLDGVDIAKMSR 466
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGYDT 467
+ LR + V Q+ ++F +I ENIA A T+ E+E AA+ A F+ +LP GYDT
Sbjct: 467 DELRAGIGMVLQDTWLFGGTIAENIAYGASREVTRGEIEEAARAAHADRFVRTLPDGYDT 526
Query: 468 VVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTA 527
V+ ++G +S G++Q I +ARA L +P I++LD+ S++D TE + + + ++ +T+
Sbjct: 527 VIDDEGTGVSAGEKQLITIARAFLSDPVILVLDEATSSVDTRTEVLIQKAMAKLAHGRTS 586
Query: 528 LIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+++ RLS ++ D ++VM+DG IVE G EL+ G ++ + KA
Sbjct: 587 FVIAHRLSTIRDADTILVMEDGAIVEQGAHTELLTADGAYARLYKA 632
>emb|CAB60586.1| (AL117200) contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=228.4, E-value=3.4e-65, N=1; PF00664
(ABC transporter transmembrane region.), Score=121.9,
E-value=3.9e-33, N=1 [Caenorhabditis elegans]
Length = 807
Score = 271 bits (685), Expect = 2e-71
Identities = 148/543 (27%), Positives = 278/543 (50%), Gaps = 3/543 (0%)
Query: 22 FLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGR 81
F L+ + N I P L + + ++ V R +++ V +
Sbjct: 233 FSAAYVLLFVDCILNLIEPALYSQMMSTAIRMKSFDVLKRACIVLAAVQFTEATVNTVRY 292
Query: 82 YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRML 141
+ A + +R+ FRAI ++ FFD +GQL+SRIT D+E I+ L +
Sbjct: 293 ICMQYAERLTARNIRVSLFRAILHQDISFFDDNKTGQLMSRITKDSESISNSLPVYIETT 352
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
+ + F++ S M + L + +T I++ Y + V + +K T V
Sbjct: 353 VNNSFMLFGSAPIMFYYSWQLAISTFVTFPIILLTTKFYGLIVEKLSEKENDATAVSNET 412
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTM 261
++ I+T++S + E+ +++++ + + ++ K + + + + +
Sbjct: 413 VEEVLSAIRTVRSFAAEKIENMRYTRDTDAWFKISTKTVVFGTFFNYFWATMWNIEDVII 472
Query: 262 FYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP 321
+ YGG + + L+ ++ Y + L A D+ +++ ++ ++ +++ P
Sbjct: 473 YLYGGYLTLNGRMEPDALLTYIFYHWRLHSALNAFSSLFSDVMKTIGSSRKVIHIMNRQP 532
Query: 322 KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPGEKVLITGPPGSGKS 379
+ +D E G I F DV Y T + VL ++ + PG+ + + GP G+GKS
Sbjct: 533 E-LDYEFGTETPEIVGNIIFEDVEFAYPTRKNANVLNKINLSIDPGKTIALVGPSGNGKS 591
Query: 380 SILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPN 439
+++ LI +FY P G +LIDG + I + +A V QEP +F+ ++RENI N
Sbjct: 592 TLVSLIQQFYTPQSGRILIDGTPIQNIDHLHYHTNIALVAQEPTLFSGTVRENILYGLEN 651
Query: 440 ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLL 499
T E++ R A++A +H+F++ + KGYDT GEKG+ +SGGQ+QRIA+ARA++ +P++++L
Sbjct: 652 GTDEDMMRVAEMANVHEFVSKMEKGYDTKCGEKGVQMSGGQKQRIAIARALIRDPRVLIL 711
Query: 500 DDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEE 559
D+ S LD+E+E + E L +++T L+++ RLS V+ DR+ V++ G + E G EE
Sbjct: 712 DEATSALDSESEAMVQEALNRCARERTVLVIAHRLSTVRSADRIAVIEKGNVTEMGNHEE 771
Query: 560 LIK 562
L+K
Sbjct: 772 LMK 774
>pir||T31617 hypothetical protein Y50E8A.m - Caenorhabditis elegans
Length = 2055
Score = 271 bits (685), Expect = 2e-71
Identities = 148/543 (27%), Positives = 278/543 (50%), Gaps = 3/543 (0%)
Query: 22 FLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGR 81
F L+ + N I P L + + ++ V R +++ V +
Sbjct: 1481 FSAAYVLLFVDCILNLIEPALYSQMMSTAIRMKSFDVLKRACIVLAAVQFTEATVNTVRY 1540
Query: 82 YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRML 141
+ A + +R+ FRAI ++ FFD +GQL+SRIT D+E I+ L +
Sbjct: 1541 ICMQYAERLTARNIRVSLFRAILHQDISFFDDNKTGQLMSRITKDSESISNSLPVYIETT 1600
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
+ + F++ S M + L + +T I++ Y + V + +K T V
Sbjct: 1601 VNNSFMLFGSAPIMFYYSWQLAISTFVTFPIILLTTKFYGLIVEKLSEKENDATAVSNET 1660
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTM 261
++ I+T++S + E+ +++++ + + ++ K + + + + +
Sbjct: 1661 VEEVLSAIRTVRSFAAEKIENMRYTRDTDAWFKISTKTVVFGTFFNYFWATMWNIEDVII 1720
Query: 262 FYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP 321
+ YGG + + L+ ++ Y + L A D+ +++ ++ ++ +++ P
Sbjct: 1721 YLYGGYLTLNGRMEPDALLTYIFYHWRLHSALNAFSSLFSDVMKTIGSSRKVIHIMNRQP 1780
Query: 322 KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPGEKVLITGPPGSGKS 379
+ +D E G I F DV Y T + VL ++ + PG+ + + GP G+GKS
Sbjct: 1781 E-LDYEFGTETPEIVGNIIFEDVEFAYPTRKNANVLNKINLSIDPGKTIALVGPSGNGKS 1839
Query: 380 SILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPN 439
+++ LI +FY P G +LIDG + I + +A V QEP +F+ ++RENI N
Sbjct: 1840 TLVSLIQQFYTPQSGRILIDGTPIQNIDHLHYHTNIALVAQEPTLFSGTVRENILYGLEN 1899
Query: 440 ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLL 499
T E++ R A++A +H+F++ + KGYDT GEKG+ +SGGQ+QRIA+ARA++ +P++++L
Sbjct: 1900 GTDEDMMRVAEMANVHEFVSKMEKGYDTKCGEKGVQMSGGQKQRIAIARALIRDPRVLIL 1959
Query: 500 DDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEE 559
D+ S LD+E+E + E L +++T L+++ RLS V+ DR+ V++ G + E G EE
Sbjct: 1960 DEATSALDSESEAMVQEALNRCARERTVLVIAHRLSTVRSADRIAVIEKGNVTEMGNHEE 2019
Query: 560 LIK 562
L+K
Sbjct: 2020 LMK 2022
>dbj|BAB04432.1| (AP001509) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 578
Score = 271 bits (685), Expect = 2e-71
Identities = 160/550 (29%), Positives = 293/550 (53%), Gaps = 11/550 (2%)
Query: 23 LIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRY 82
LIG + L+ T +P+L R +D G S + + ++++ + L V Y
Sbjct: 30 LIGSLITTLVGLT---IPLLTREMVD-GFSLESLNTLLIAAIIVVFI--LQAVLDGLSMY 83
Query: 83 LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLL 142
L Q V LR + + R + +FDK SGQ +SR+ NDT + +S +
Sbjct: 84 ALAYVGQKIVARLRERMWFKLLRLPVNYFDKNTSGQTVSRVVNDTGIVKDLISQHFPQFV 143
Query: 143 YSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIA 202
I II ++ + M+ +T++ I + I V + M++ I ++ +T
Sbjct: 144 GGIITIIGAVIILFIMDWKMTLLMFIAVPITVAVMVPLGMRMSKISRGLQDETANFTGNV 203
Query: 203 TGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMF 262
T++ I+ +K+ + E+ + K E+L+S ++ KI AL +LV+ + + +
Sbjct: 204 QQTLSEIRLMKASNAEQTEEKKGLTGIEKLFSFGLREGKIFALIAPLMYLVVMVVIVIII 263
Query: 263 YYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK 322
YGG + + T+T G LVAFL Y+ +++P+ + +Q++ A R+ +++D +
Sbjct: 264 GYGGIRVAEGTMTTGSLVAFLLYLFQIIFPITSFTMFFTQLQKAKGATERIIEILDIEEE 323
Query: 323 SIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSIL 382
+ ++ISN I ++V Y+ V++ VSF V+PG V GP G GK+++
Sbjct: 324 NGQQGLEMDISNK--AIHVKNVSFAYNEEEPVIQKVSFDVEPGTMVAFAGPSGGGKTTMF 381
Query: 383 KLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA---KPN 439
L+ RFY+PT GE+LI ++ ++ + RK + YV Q+ + +IREN+ + +
Sbjct: 382 GLLERFYEPTSGEILIGDTSIQELSMYSWRKQIGYVSQDSPMMVGTIRENLCYGLEDRDD 441
Query: 440 ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLL 499
+ + AK+A FI+ PKG DT VGE+G+ LSGGQRQRIA+ARA L +PKI+++
Sbjct: 442 IDDDRLWEVAKMAYADQFISEFPKGLDTEVGERGVKLSGGQRQRIAIARAFLRDPKILMM 501
Query: 500 DDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEE 559
D+ ++LD+++E + + L +++ +T +++ RLS + D++I ++ G+I G +E
Sbjct: 502 DEATASLDSQSEGIVQQALTRLMEGRTTFVIAHRLSTIVNADKIIFIEKGQITGIGTHQE 561
Query: 560 LIKKGGIFSE 569
L++ ++ E
Sbjct: 562 LVQTHDLYRE 571
>pir||H72425 ABC transporter, ATP-binding protein - Thermotoga maritima (strain
MSB8) >gi|4980528|gb|AAD35137.1|AE001691_11 (AE001691)
ABC transporter, ATP-binding protein [Thermotoga
maritima]
Length = 581
Score = 271 bits (685), Expect = 2e-71
Identities = 176/573 (30%), Positives = 295/573 (50%), Gaps = 17/573 (2%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYG------L 64
LL Y + + FL+G L ++++ + P L++ AIDK + R
Sbjct: 9 LLRYAKKYWYLFLVGTVLSLILTVMEILPPRLMKTAIDKFLVESTLSSFERLNGIVITAF 68
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
+IL + VL+ + A Y+ A V +R D F + FF SG + +RI
Sbjct: 69 IILGIRVLSFLVGFASSYVTGYAGSRIVLLMRKDVFSHVISLPYSFFTGIPSGVVTTRIV 128
Query: 125 NDTERITRFLSFRVRMLLYSIFL---IIISLYYMVR--MNITLTMVALITIAIVVGLNTT 179
NDT+ I F S V ++ + L +++SL + R ++ LI I+I++
Sbjct: 129 NDTQNIQEFFSSVVTSVIMDVLLLGAVVVSLVQLSRELFGHVYYLLPLIVISILL----- 183
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
+ R Y K+R + + IAGI K L++E++ + +FS E Y ++
Sbjct: 184 FRYFDRRAYRKVRTNLARLNAFLAEHIAGINVTKILNLEKHKEREFSTVATEYYRSLMEQ 243
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
+ + ++ + L +S + +YG + I TL G L AF++Y+ PLR L
Sbjct: 244 LYVFGVFRPLMDFLYFLGVSLVLWYGARYIANKTLGFGSLYAFVSYLDMFFRPLRDLSEK 303
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVS 359
IQ S+A++ ++ +++ P+ I P+ + +G + F +VW +Y VLK ++
Sbjct: 304 YDIIQNSMASSEKILNLLKEEPEVIGNPNGPNKIS-KGRVRFENVWFSYDGKNWVLKDIN 362
Query: 360 FKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVP 419
+PG+ I G G GKS+++ LI Y P KG + ID + + + + +RK +A VP
Sbjct: 363 LDFQPGKLYAIVGETGGGKSTLMSLINGLYIPQKGNIFIDEIPLLEYNLKLVRKQIAAVP 422
Query: 420 QEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
Q+ +F+ +I +NI L + +E V A K D I LP G + E+G TLS G
Sbjct: 423 QDVLLFSGTILDNIRLFDESIPEERVLEALKRVHALDIIERLPGGVYYEIVERGTTLSAG 482
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKL 539
+RQ IALARA+L + KI +LD+ SN+D TE K+ E L+E+ +D+T ++++ RLS VK
Sbjct: 483 ERQLIALARAVLFDAKIFILDEATSNVDVITETKIQEALEELSKDRTVIMIAHRLSTVKD 542
Query: 540 VDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
VD ++V+ +G+IVE G EL++K G + + K
Sbjct: 543 VDEIVVVHNGRIVEKGNHYELLEKRGFYYNLYK 575
>sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA >gi|281879|pir||S27998
probable ABC-type transport protein msbA - Escherichia
coli >gi|42023|emb|CAA77839.1| (Z11796) member of
ATP-dependent transport family, very similar to mdr
proteins and hemolysin B, export protein [Escherichia
coli] >gi|1651441|dbj|BAA35658.1| (D90729) MsbA protein.
[Escherichia coli] >gi|1787143|gb|AAC74000.1| (AE000193)
ATP-binding transport protein; multicopy suppressor of
htrB [Escherichia coli K12]
Length = 582
Score = 270 bits (684), Expect = 2e-71
Identities = 169/552 (30%), Positives = 304/552 (54%), Gaps = 16/552 (2%)
Query: 29 IILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAA 88
+IL + +++ + L++ +D G V + L+++ + +L G+ S Y + +
Sbjct: 34 LILNAASDTFMLSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVS 93
Query: 89 QYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFR----VRMLLYS 144
V +R F + + FFDK +G L+SRIT D+E++ S VR
Sbjct: 94 GKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASI 153
Query: 145 IFLIIISLYYMVRMNITLTMVA-LITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIAT 203
I L I+ YY +++I L ++A +++IAI V + + R I +++ G + + A
Sbjct: 154 IGLFIMMFYYSWQLSIILIVLAPIVSIAIRV-----VSKRFRNISKNMQNTMGQVTTSAE 208
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
+ G K + +E +F + + + +K + +++ L+ LA++ + Y
Sbjct: 209 QMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLY 268
Query: 264 YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKS 323
+ ++LT G + + M+ +M PL++L QR +AA LF ++DS +
Sbjct: 269 AASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEK 328
Query: 324 IDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSI 381
+ +E + G++EFR+V TY GR V L+ ++ K+ G+ V + G GSGKS+I
Sbjct: 329 DEGKRVIERAT--GDVEFRNVTFTY-PGRDVPALRNINLKIPAGKTVALVGRSGSGKSTI 385
Query: 382 LKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNA- 440
LI RFY +GE+L+DG ++ + +LR VA V Q +FN ++ NIA A+
Sbjct: 386 ASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQY 445
Query: 441 TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLD 500
++E++E AA++A DFI + G DTV+GE G+ LSGGQRQRIA+ARA+L + I++LD
Sbjct: 446 SREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILD 505
Query: 501 DPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEEL 560
+ S LD E+E+ + L E+ +++T+L+++ RLS ++ D ++V++DG IVE G +L
Sbjct: 506 EATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDL 565
Query: 561 IKKGGIFSEMMK 572
++ G+++++ K
Sbjct: 566 LEHRGVYAQLHK 577
>gb|AAA91199.1| (L76468) ABC-transporter [Gorilla gorilla]
Length = 748
Score = 270 bits (684), Expect = 2e-71
Identities = 170/575 (29%), Positives = 302/575 (51%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 171 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 230
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R EMEFF + +G + SR+T
Sbjct: 231 MSVLTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQEMEFFQQNQTGNITSRVTE 290
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV L+T+ ++ L +
Sbjct: 291 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQ 350
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 351 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 410
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + + L +Q+
Sbjct: 411 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQK 470
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F +
Sbjct: 471 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLH 529
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 530 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 589
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA + H FI+ LP+GYDT VGE G LSGGQ
Sbjct: 590 VFGRSLQENIAYGLTQKP--TMEEITAAAVKSGAHSFISGLPQGYDTEVGEAGSQLSGGQ 647
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
RQ +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 648 RQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 707
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 708 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 742
>gb|AAC12903.1| (L21205) peptide transporter [Homo sapiens]
>gi|3036970|gb|AAC12904.1| (L21206) peptide transporter
[Homo sapiens]
Length = 748
Score = 270 bits (684), Expect = 2e-71
Identities = 169/575 (29%), Positives = 303/575 (52%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 171 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 230
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R E EFF + +G ++SR+T
Sbjct: 231 MSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTE 290
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV L+T+ ++ L +
Sbjct: 291 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQ 350
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 351 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 410
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + + L +Q+
Sbjct: 411 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQK 470
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F ++
Sbjct: 471 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLR 529
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 530 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 589
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA + H FI+ LP+GYDT VGE G LSGGQ
Sbjct: 590 VFGRSLQENIAYGLTQKP--TMEEITAAAVKSGAHSFISGLPQGYDTEVGEAGSQLSGGQ 647
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
RQ +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 648 RQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 707
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 708 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 742
>gb|AAG11416.1|AF263455_1 (AF263455) TagA [Dictyostelium discoideum]
Length = 1702
Score = 270 bits (684), Expect = 2e-71
Identities = 162/558 (29%), Positives = 292/558 (52%), Gaps = 18/558 (3%)
Query: 24 IGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVA---IRYGLLIL---LVGVLNGVF- 76
+ LFL + VP++ N D + K++ + + L+I+ +V L+G+
Sbjct: 1065 LALFLSFIDVALGLAVPLVAANIFDYLYAGETGKISTTILTFALIIIGMIIVQFLSGILL 1124
Query: 77 SLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSF 136
+LAG ++ + LR + F ++ + +M FF++ +G+L+SR+ +D + +S
Sbjct: 1125 ALAGHRIIAR--------LRREMFASLLKQDMAFFNERKTGELMSRLASDVSSVRSIISD 1176
Query: 137 RVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTG 196
+ ++ I I +L + ++ L++V L + I++ + Y + I K++
Sbjct: 1177 SIPHMIIQIATIGGTLIMLFIISWKLSLVVLCPLPILLVFSKFYGGYIEVISVKVQDALA 1236
Query: 197 VIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGL 256
A+ A T+ +KT++ S EE KFS+ Y + +K +Y + + L
Sbjct: 1237 DAATHAAETLFNMKTVRWFSAEEREVAKFSKLISVSYKIALKMTIWNGIYSSTSGIFEQL 1296
Query: 257 AMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDV 316
++ + +YG + LT L+AF ++ + + + + ++ R F++
Sbjct: 1297 SVFILLWYGSSLVSNGDLTPSMLIAFNLFLPFITGAVTQVASLYTTYKSYKGSSYRFFEI 1356
Query: 317 IDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPP 374
+ P I + + RG+I+F V Y + + VL+ + K +PG + GP
Sbjct: 1357 MQRVP-DIQGEGGITRTKVRGDIQFNKVSFAYSSNPDQLVLEKIDIKFEPGTITALIGPS 1415
Query: 375 GSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIA 434
G GKS++L LI R Y G + +DG N+ NL + ++ V QEP +F+ SI ENI
Sbjct: 1416 GGGKSTMLSLIGRLYNIDGGSITLDGTNIKDFNVPNLHEHISIVNQEPSLFSGSIAENIM 1475
Query: 435 LAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNP 494
KP AT+ E+ A K A HDFI ++P+GYDT++GE+G LSGGQ+QRIA+AR ++ NP
Sbjct: 1476 FGKPTATRSEIIEACKQANAHDFITAMPEGYDTLIGERGTALSGGQKQRIAIARTIIKNP 1535
Query: 495 KIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVED 554
++LLD+ S LD E+EK + + + +++ +T +IV+ RL+ + D + V+ D I E
Sbjct: 1536 TVLLLDETTSELDVESEKLVQDSIDKLVVGRTVIIVAHRLTTILTADIIAVVSDSTISEM 1595
Query: 555 GKPEELIKKGGIFSEMMK 572
G PEEL+ K G+F + ++
Sbjct: 1596 GTPEELLAKKGMFYDFVQ 1613
>gb|AAC12905.1| (L21207) peptide transporter [Homo sapiens]
Length = 748
Score = 270 bits (683), Expect = 3e-71
Identities = 169/575 (29%), Positives = 303/575 (52%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 171 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 230
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R E EFF + +G ++SR+T
Sbjct: 231 MSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTE 290
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV L+T+ ++ L +
Sbjct: 291 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQ 350
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 351 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 410
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + L L +Q+
Sbjct: 411 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQALEVLLSIYPRVQK 470
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F ++
Sbjct: 471 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLR 529
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 530 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 589
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA + H FI+ LP+GYDT VGE G LSGGQ
Sbjct: 590 VFGRSLQENIAYGLTQKP--TMEEITAAAVKSGAHSFISGLPQGYDTEVGEAGSQLSGGQ 647
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
+Q +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 648 QQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 707
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 708 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 742
>gb|AAD55753.1|AF108387_1 (AF108387) transporter associated with antigen processing 1
[Heterodontus francisci]
Length = 558
Score = 270 bits (682), Expect = 4e-71
Identities = 145/483 (30%), Positives = 272/483 (56%), Gaps = 9/483 (1%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
++ FR++ R E+ FFD +G + SRIT DT ++ L+ ++ +L++ + + L +
Sbjct: 60 IQSSVFRSVVRQEIAFFDTVHTGDITSRITTDTNTMSESLTEKLSLLMWYLMRAVCLLAF 119
Query: 155 MVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKS 214
M ++ LT+ LI I I++ + + + +++ +A T +KT++S
Sbjct: 120 MFNLSWKLTICTLIGIPIIIIIPEFTGKYYQKLSVEVQESLAKANDVAVETFLSMKTVRS 179
Query: 215 LSVEENVQTKFSQENEELYSLNVKAMKITA--LYGNAPFLVLGLAMS-TMFYYGGKAIIQ 271
+ E+ ++ + E+ + LN K A ++ N+ + GL + T+ YYGG+ +
Sbjct: 180 FANEDGESRRYGERLEDTFRLNKKEAAAYAGFMWTNS---LSGLVLKVTLLYYGGRLVAG 236
Query: 272 NTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVE 331
+T G LV+F+ Y + + L ++++++ A+ ++F+ +D P ++
Sbjct: 237 GNVTSGNLVSFILYEMQFTTAVEVLLSVYPNVKKAVGASEKVFEYMDRRP-ALSTVGTFA 295
Query: 332 ISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFY 389
P+ IEFR+V Y VLK VSF++K G+ + GP G GK++ + L+ RFY
Sbjct: 296 PVRPKAHIEFRNVTFAYPKRPDTPVLKNVSFELKCGKITALVGPSGGGKTTCVSLLERFY 355
Query: 390 KPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAA 449
+P G++L+DG + + + + V+ V QEP +F RS+ +NI+ +E V AA
Sbjct: 356 QPQSGQILLDGKPIKEYEHKYYHNKVSLVSQEPVLFARSVEQNISYGLEGKPRESVIDAA 415
Query: 450 KIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAE 509
K A H FI L GY+T GEKG LSGGQ+QR+A+ARA++ +P++++LDD S LD E
Sbjct: 416 KRANAHRFITELKDGYNTDAGEKGGQLSGGQKQRVAIARALIRDPRVLILDDATSCLDTE 475
Query: 510 TEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSE 569
+E +++ + + + L+++ RLS ++ D ++V+++G +VE G +EL++KGG + +
Sbjct: 476 SEHMVLQSVYNGDRQRAVLVIAHRLSTMEGADWIVVLENGSVVEQGTHQELLQKGGSYQQ 535
Query: 570 MMK 572
+++
Sbjct: 536 LLQ 538
>gi|6005804 ATP-binding cassette, sub-family B, member 8; mitochondrial ABC
protein [Homo sapiens] >gi|4321407|gb|AAD15748.1|
(AF047690) ATP-binding cassette protein M-ABC1 [Homo
sapiens]
Length = 718
Score = 270 bits (682), Expect = 4e-71
Identities = 155/512 (30%), Positives = 273/512 (53%), Gaps = 5/512 (0%)
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
L++L GV G+ + LL + +R F ++ R + FFD +GQL+SR+T
Sbjct: 181 LLILYGV-QGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQNITFFDANKTGQLVSRLT 239
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
D + + L S + L + ++ LT++ ++ ++G+ T +
Sbjct: 240 TDVQEFKSSFKLVISQGLRSCSQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGL 299
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
R + + + +A + ++T+++L++E+ + ++ E E + + A
Sbjct: 300 RKLSRQCQEHIARAMGVADEALGNVRTVRALAMEQREEERYGAELEACRCRAEELGRGIA 359
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
L+ + + + GG + LT G+L++FL T+ + L G +
Sbjct: 360 LFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVV 419
Query: 305 RSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFK 361
R L+A +R+F+ + P + V RG + F++V +Y G VLK +
Sbjct: 420 RGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLT 479
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR-KIVAYVPQ 420
+ PG+ V + G G GK+++ L+ RFY PT G V++DG ++ + LR ++V ++ Q
Sbjct: 480 LPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQ 539
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
EP +F +I ENI K A+ EEV AA+ A H+FI S P+GY+TVVGE+G TLSGGQ
Sbjct: 540 EPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQ 599
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
+QR+A+ARA++ P +++LD+ S LDAE+E+ + E L +T L+++ RLS V+
Sbjct: 600 KQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGA 659
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
++VM DG++ E G EEL+KKGG+++E+++
Sbjct: 660 HCIVVMADGRVWEAGTHEELLKKGGLYAELIR 691
>pir||T34038 hypothetical protein F43E2.4 - Caenorhabditis elegans
>gi|1947137|gb|AAC71121.1| (AF000264) similar to the
ATP-binding transport protein family (ABC transporters).
[Caenorhabditis elegans]
Length = 761
Score = 269 bits (680), Expect = 7e-71
Identities = 161/557 (28%), Positives = 288/557 (50%), Gaps = 6/557 (1%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
L+RLLSY F G + + + +P I V+ + I +++
Sbjct: 185 LLRLLSYCGHQWPWFASGFVFLTVYALARVFIPNYTAQVISDIVNKRGIQALIHSIIVLT 244
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
+ + +F A +R+D F ++ R ++ F+D +G +SR+T+D
Sbjct: 245 CLTATSSLFGGLRGGCFDYATALVTLRIRLDLFTSLIRQDIAFYDTAKTGDTMSRLTSDC 304
Query: 128 ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
+ I+ +S V + + + ++I +L +M+ M+ L MV I + +V + Y+ I
Sbjct: 305 QTISSTVSTNVNVFMRNGVMLIGALAFMILMSWRLAMVTFIAVPLVGFITKAYSSFYDKI 364
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYG 247
+K++ +A ++ ++T++S + E+ +F S+N K Y
Sbjct: 365 SEKLQQTIAETNQMAEEVVSTMRTVRSFACEKKELKRFEDRLSSTLSVNRKKSIAYLFYT 424
Query: 248 -NAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRS 306
N F + ++ +FY GG ++ + +L+ FL Y + + L L + + + +
Sbjct: 425 WNNEFCDNAILVAVLFY-GGHLVMTGKMEKEQLITFLLYQMQLGENLYYLSYVMSGLMEA 483
Query: 307 LAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKGVSFKVKP 364
+ A+ ++FD+++ P+ D ++ G I F V TY + VLK ++ +K
Sbjct: 484 VGASRKVFDLMNRKPQF--ELDGMQRPFVNGNITFSHVGFTYPSRPNNPVLKDLTLSIKS 541
Query: 365 GEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI 424
GE V + GP G GKSSI+ LI FY+P +G V +DGV + I + VA V QEP +
Sbjct: 542 GETVALVGPSGGGKSSIVSLIEHFYEPDEGSVTLDGVPIKDINHVYYHQKVALVAQEPVL 601
Query: 425 FNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRI 484
+N S+R NI AT++++ A+K+A +HDF+ L KGYDT GEKG+ +SGGQ+QRI
Sbjct: 602 YNGSVRHNILYGCDFATEDDMLNASKMANVHDFVMELEKGYDTNCGEKGVQMSGGQKQRI 661
Query: 485 ALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVI 544
A+ARA++ NP +++LD+ S LD E+E + + L Q++T +IV+ RLS ++ +++
Sbjct: 662 AIARALVRNPAVLILDEATSALDTESEALVQQALSRCAQERTVIIVAHRLSTIEKANKIA 721
Query: 545 VMKDGKIVEDGKPEELI 561
V+ G +V+ G EL+
Sbjct: 722 VIVKGCLVQMGTHTELM 738
>sp|Q03518|TAP1_HUMAN ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (PEPTIDE TRANSPORTER TAP1)
(PEPTIDE TRANSPORTER PSF1) (PEPTIDE SUPPLY FACTOR 1)
(PSF-1) (PEPTIDE TRANSPORTER INVOLVED IN ANTIGEN
PROCESSING 1) >gi|34636|emb|CAA47025.1| (X66401)
ABC-transporter [Homo sapiens]
>gi|1054745|emb|CAA60785.1| (X87344) TAP1 [Homo sapiens]
>gi|3036968|gb|AAC12902.1| (L21204) peptide transporter
[Homo sapiens]
Length = 748
Score = 268 bits (678), Expect = 1e-70
Identities = 169/575 (29%), Positives = 302/575 (52%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 171 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 230
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R E EFF + +G ++SR+T
Sbjct: 231 MSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTE 290
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV LIT+ ++ L +
Sbjct: 291 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLITLPLLFLLPKKVGKWYQ 350
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 351 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 410
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + + L +Q+
Sbjct: 411 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQK 470
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F ++
Sbjct: 471 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLR 529
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 530 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 589
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA + H FI+ LP+GYDT V E G LSGGQ
Sbjct: 590 VFGRSLQENIAYGLTQKP--TMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQ 647
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
RQ +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 648 RQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 707
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 708 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 742
>gi|9665248 ATP-binding cassette, sub-family B, member 2; antigen peptide
transporter [Homo sapiens] >gi|11417934|ref|XP_004227.1|
ATP-binding cassette, sub-family B, member 2 [Homo
sapiens] >gi|1082241|pir||A41538 ATP-binding cassette
transporter TAP1 - human >gi|36061|emb|CAA40741.1|
(X57522) peptide transporter [Homo sapiens]
>gi|227427|prf||1703418A RING4 gene [Homo sapiens]
Length = 808
Score = 268 bits (678), Expect = 1e-70
Identities = 169/575 (29%), Positives = 302/575 (52%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 231 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 290
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R E EFF + +G ++SR+T
Sbjct: 291 MSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTE 350
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV LIT+ ++ L +
Sbjct: 351 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLITLPLLFLLPKKVGKWYQ 410
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 411 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 470
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + + L +Q+
Sbjct: 471 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQK 530
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F ++
Sbjct: 531 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLR 589
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 590 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 649
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA + H FI+ LP+GYDT V E G LSGGQ
Sbjct: 650 VFGRSLQENIAYGLTQKP--TMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQ 707
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
RQ +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 708 RQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 767
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 768 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 802
>gb|AAA91198.1| (L76470) ABC-transporter [Gorilla gorilla]
Length = 747
Score = 268 bits (678), Expect = 1e-70
Identities = 169/575 (29%), Positives = 300/575 (51%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 171 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 230
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R E EFF + +G + SR+T
Sbjct: 231 MSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNITSRVTE 290
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV L+T+ ++ L +
Sbjct: 291 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQ 350
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 351 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 410
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + + L +Q+
Sbjct: 411 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQK 470
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F +
Sbjct: 471 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLH 529
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 530 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 589
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA H FI+ LP+GYDT VGE G LSGGQ
Sbjct: 590 VFGRSLQENIAYGLTQKP--TMEEITAAAVKCGAHSFISGLPQGYDTEVGEAGSQLSGGQ 647
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
RQ +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 648 RQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 707
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 708 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 742
>pir||T31078 probable ABC-transporter TycE - Brevibacillus brevis
>gi|2623775|gb|AAC45932.1| (AF004835) putative
ABC-transporter TycE [Brevibacillus brevis]
Length = 583
Score = 268 bits (678), Expect = 1e-70
Identities = 165/545 (30%), Positives = 286/545 (52%), Gaps = 23/545 (4%)
Query: 31 LMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQY 90
L + +S P L+ AI + + LL +L+ FS Y+ + +
Sbjct: 33 LTDFASSKDPALLTRAI------------VTMAAMFLLFSLLSPFFS----YIYRRCVRE 76
Query: 91 AVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIII 150
V +R+ F+ + R ++++ SG +SR+ ND + + R + +++ L + ++
Sbjct: 77 VVANIRLLVFQRLSRLPFAYYEQHHSGDTMSRLGNDVQLMERAYAEQLKTLCIIMLSLVG 136
Query: 151 SLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIK 210
S+ M ++ + V L+ + + +N +A VR I D+++ Q G + +AG+
Sbjct: 137 SIVGMFALDGKIATVLLLVSTLTLYVNAQFAKSVRRIGDQMQQQLGTGTERLSDFLAGLP 196
Query: 211 TIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAII 270
IK +++ V ++++ NE++ +K AL F + ++ M +G +
Sbjct: 197 VIKMFHLQKVVTARYTEANEQVTLSAIKQGHKHALLEGTNFFIQFVSFGGMLVFGIMMVA 256
Query: 271 QNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSA--PKSIDP-- 326
+ + +G LVA + + + LG I +Q SLA ASR+ + PK +P
Sbjct: 257 KQMIGLGVLVAMVQQQMLVTLAFLQLGQVITTLQGSLAGASRIVGFLQEPLEPKRYEPAS 316
Query: 327 -PDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLI 385
P A I + +E D T T VL+GVS +V G+ + G G GKS+++KL+
Sbjct: 317 APTATRIYDSMLTVEQVDFGYTADT--KVLQGVSLQVGRGQMAALVGTSGGGKSTVMKLL 374
Query: 386 ARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEV 445
+Y P+ G + + G + + +R +++YVPQ+ F+F +I ENI +AT+EEV
Sbjct: 375 LGYYPPSAGSLPLLGKPIGQYSIAEMRSLISYVPQDAFLFEGTIEENIRYGCLDATEEEV 434
Query: 446 ERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSN 505
RA+K A HDFI LP GY T GE+G LSGGQRQRIA+ARA+L N I+LLD+ S
Sbjct: 435 IRASKAAYAHDFIMELPDGYQTRTGERGAKLSGGQRQRIAIARAILKNAPILLLDEATSA 494
Query: 506 LDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGG 565
LD E+E + L ++Q+KT L+++ RLS ++ D + V+ +GK++E G+ EL+ + G
Sbjct: 495 LDTESEFWVQRALAALMQEKTVLVIAHRLSTIEHADMIYVLHEGKVMEQGRHAELLAQNG 554
Query: 566 IFSEM 570
+++ M
Sbjct: 555 LYASM 559
>dbj|BAB04877.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 674
Score = 268 bits (678), Expect = 1e-70
Identities = 161/513 (31%), Positives = 280/513 (54%), Gaps = 10/513 (1%)
Query: 64 LLILLVG--VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
LL+ G V+ F R+ L KAA + LR+D F + R + FFD +G+++S
Sbjct: 151 LLLFYFGLMVVASFFQYGQRFYLQKAANRIIQRLRIDLFNHLSRLPVRFFDNMPAGKVVS 210
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYY-MVRMNITLTMVALITIAIVVGLNTTY 180
RITNDTE I R L V ++ + +I +Y M +++ L + L I I+V Y
Sbjct: 211 RITNDTEAI-RELYVAVLANFFTSIIYMIGIYIAMFLLDVRLAFICLGLIPILVLWIVLY 269
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
I +IR + I + I G+ I++ E++ F + N+ Y VK +
Sbjct: 270 RKYASAINHRIRSKISEINASMNENIQGMSIIQAFVREKDSADTFDRLNDSHYRDQVKLL 329
Query: 241 KITALYG-NAPFLVLGLAMSTMFYY--GGKAIIQNTLTVGELVAFLTYMLTMMWPLRALG 297
++ AL G N +++ L + + G + LT+G L AF+ Y+ + P+ +
Sbjct: 330 RLNALTGHNLSWVLRNLVFVGLIWSIAGTSLGAGSALTLGVLYAFVDYVNRLFEPVNRIV 389
Query: 298 FTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKG 357
+ +++++ A R+F+++D + I P+G++ F +V Y VLK
Sbjct: 390 HQLPNLEQARVAGERVFELMDKEGTEVSDET---IPRPKGDVVFDNVSFAYKENEKVLKN 446
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
++F KPG+ + + G GSGKSSI+ L+ RFY +G++ IDG ++ +I + LR+ +
Sbjct: 447 LTFHAKPGQTIGLVGHTGSGKSSIMNLLFRFYDSDEGQIRIDGQDIKEISPQALRQHMGI 506
Query: 418 VPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLS 477
V QEP++F ++ N++L+ P T+E +E A ++ A L +G D V EKG TLS
Sbjct: 507 VLQEPYLFTGTVASNLSLSNPAITREAMEEALRLVDGEHVFADLEQGLDEEVKEKGSTLS 566
Query: 478 GGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLV 537
GQRQ I+ ARA++ +P I++LD+ SN+D+ETE + L+ + + +T +++ RLS +
Sbjct: 567 SGQRQLISFARALVADPAILVLDEATSNIDSETEAIIQRGLEALKRGRTTFVIAHRLSTI 626
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
K D+++V+ GKI+E G +EL+++ G +++M
Sbjct: 627 KNADQILVLDKGKIIESGTHDELMEQEGAYAQM 659
>gb|AAC12906.1| (L21208) peptide transporter [Homo sapiens]
Length = 748
Score = 268 bits (677), Expect = 2e-70
Identities = 168/575 (29%), Positives = 302/575 (52%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 171 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 230
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R E EFF + +G ++SR+T
Sbjct: 231 MSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTE 290
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV L+T+ ++ L +
Sbjct: 291 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQ 350
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 351 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 410
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + + L +Q+
Sbjct: 411 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQK 470
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F ++
Sbjct: 471 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLR 529
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 530 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 589
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA + H FI+ LP+GYDT V E G LSGGQ
Sbjct: 590 VFGRSLQENIAYGLTQKP--TMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQ 647
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
RQ +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 648 RQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 707
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 708 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 742
>gi|9506367 ATP-binding cassette, sub-family B, member 12; Abc-mitochondrial
erythroid [Mus musculus]
>gi|8571454|gb|AAF76889.1|AF266284_1 (AF266284) ABC
transporter [Mus musculus]
Length = 715
Score = 268 bits (677), Expect = 2e-70
Identities = 186/583 (31%), Positives = 301/583 (50%), Gaps = 19/583 (3%)
Query: 2 RKSINQLIRLLSYLRGH---AVHFLIGLFLIILMS---YTNSIVPVLIRNAIDKGVSTGA 55
R + +L+ L+ RG AV FL + +I MS + I+ V+ N +G
Sbjct: 119 RSEVWKLLGLVRPERGRLSAAVGFL-AVSSVITMSAPFFLGRIIDVIYTNP-SEGYGDSL 176
Query: 56 YKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTF 115
++ + L NG+ YL+ + Q V LR F +I R E+ FFDKT
Sbjct: 177 TRLCAVLTCVFLCGAAANGIRV----YLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTR 232
Query: 116 SGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVG 175
+G+LI+R+++DT + R ++ + L + + + M ++ +L L + +
Sbjct: 233 TGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGVGMMFFVSPSLATFVLSVVPPISV 292
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
L Y +R + + +A I I+TI++ E K++ ++L L
Sbjct: 293 LAVIYGRYLRKLSKATQDSLAEATQLAEERIGNIRTIRAFGKEMTEVEKYTGRVDQLLQL 352
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
K A + A L L + ++ Y GG + +TVGEL +FL Y + +
Sbjct: 353 AQKEALARAGFFGAAGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGG 412
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHTGR-- 352
L ++ + L A RL+++++ P+ + ++ +G +EFR+V TY
Sbjct: 413 LSSFYSELMKGLGAGGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYPARPEV 472
Query: 353 TVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR 412
+V + S + G + GP GSGKS+++ L+ R Y P G V +DG ++ ++ LR
Sbjct: 473 SVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLR 532
Query: 413 KIVAYVPQEPFIFNRSIRENIALAKPN---ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
+ V QEP +F+ S+ ENIA N T ++VERAA++A +FI S P+G+DTVV
Sbjct: 533 SKIGTVSQEPVLFSCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVV 592
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
GEKGI LSGGQ+QRIA+ARA+L NPKI+LLD+ S LDAE E + E L +++ +T LI
Sbjct: 593 GEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEGRTVLI 652
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEE-LIKKGGIFSEMM 571
++ RLS +K + V V+ GKI E G EE L+K G++ ++M
Sbjct: 653 IAHRLSTIKNANFVAVLDHGKICEHGTHEELLLKPNGLYRKLM 695
>pir||S77239 ABC-type transport protein sll1276 - Synechocystis sp. (strain PCC
6803) >gi|1652653|dbj|BAA17573.1| (D90907) ABC
transporter [Synechocystis sp.]
Length = 534
Score = 267 bits (675), Expect = 3e-70
Identities = 154/514 (29%), Positives = 281/514 (53%), Gaps = 14/514 (2%)
Query: 65 LILLVGVLNGVFSLAGRY------LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQ 118
++++ GV G+F + G L+ KAA LR + +QR + +F++ +G
Sbjct: 16 ILIMAGVAAGIFLVRGMAQYGQDTLMAKAALNMALTLREQTYAHLQRLSLSYFEEAKTGD 75
Query: 119 LISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNT 178
L R+T D +RI ++ + S +++ YM +N LT L+ ++ L
Sbjct: 76 LSYRLTEDIDRIGEVVNKLFHDFVPSALQLVVVFGYMFYLNWALTCAVLVIAPLMAVLIG 135
Query: 179 TYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+ ++ + + + ++S+ T T+ I+ +K+ + E+ F +E ++
Sbjct: 136 FFGEQLLKFSRRSQTRISNLSSLLTETLGAIRLVKAFAAEDYQLDLFREEAQQHRRSQFL 195
Query: 239 AMKITALYGNAPFLVLG----LAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
A ++ AL F+V+G + + +F I LT E ++++T + ++ P+
Sbjct: 196 AERMKALQ----FVVVGFLEAMGVVVLFCLAAWQISLGNLTGIEFISYVTGVAMLIDPIS 251
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+ ++ A+ R+F++ D P D P A+ I + +G +++ V Y + V
Sbjct: 252 HITSNYNLFKQGEASVDRIFEIFDLQPSVEDSPTAIAIDHLQGAVDYDHVDFAYLEDKLV 311
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
LKG++ + +PGE + + G G+GKS+++ L+ R + T G + IDG + I ++LR+
Sbjct: 312 LKGINLQAQPGEMIALVGASGAGKSTLVNLLMRLHNVTGGCLRIDGHAIDSITLKSLREQ 371
Query: 415 VAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGI 474
+A VPQE +F+ +I +NIA K + +E AA+IA H FI L +GY T VGE+G+
Sbjct: 372 IAIVPQENILFSGTIAQNIAFGKTDLDLAAIEEAARIANAHQFITELSQGYYTYVGERGV 431
Query: 475 TLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRL 534
TLSGGQRQRIA+ARA+L NP I++LD+ S LD+E+E + E L+ I+Q++T +++ RL
Sbjct: 432 TLSGGQRQRIAIARAVLRNPSILILDEATSALDSESEALVQEALERIVQERTVFVIAHRL 491
Query: 535 SLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFS 568
+ V+ R++V++ G+IVE G +EL+ G ++
Sbjct: 492 ATVRKATRIVVLERGEIVEMGSHQELMAHQGRYA 525
>dbj|BAB06055.1| (AP001515) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 585
Score = 266 bits (674), Expect = 3e-70
Identities = 158/557 (28%), Positives = 298/557 (53%), Gaps = 20/557 (3%)
Query: 25 GLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLA--GRY 82
G+ ++ ++S + P ++ +D Y+ + +L+ +GVL + + RY
Sbjct: 21 GIVMLAIVSLLTLVPPRVVGIIVDH-----IYEGTLTMPVLLQWIGVLAALALIVYVARY 75
Query: 83 L----LVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRV 138
L + A+ LR + F+ K +G L++ TND I V
Sbjct: 76 LWRVMIFGASLRLARLLRNQLYTHFTNMAAPFYQKHRTGDLMAHATNDIRAIQATAGQGV 135
Query: 139 RMLLYSIFLI-IISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGV 197
L+ S+ + + L + ++ LT+++L+ + ++ L + Y ++ + H
Sbjct: 136 LTLVDSLTMGGFVILTMAITISWELTLISLLPMPLMALLTSYYGSL---LHKRFHHAQAA 192
Query: 198 IASI---ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVL 254
+S+ ++ G++ K+ EE F ++++++ NV ++ AL+ L++
Sbjct: 193 FSSLNDKVQESVTGVRVTKAFGQEEQDIEAFRKQSDDVVKKNVAVARVDALFDPTISLIV 252
Query: 255 GLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLF 314
GL+ +G + +I LT+G+L +F Y+ ++WP+ A GF ++R A+ +R+
Sbjct: 253 GLSYFLAIVFGARFVIAEQLTIGQLTSFTIYLGLLIWPMLAFGFLFNIVERGRASYNRVS 312
Query: 315 DVIDSAPKSIDPPDAVEISNPRGEIEFR-DVWLTYHTGRTVLKGVSFKVKPGEKVLITGP 373
++ + + D + + P G ++ D ++ + L V F++ GE + I G
Sbjct: 313 QLLQAKQEITDSRARIHVP-PTGHVDVAIDQFVYPNQKEPALADVQFELSEGETLGIVGK 371
Query: 374 PGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENI 433
G+GK+++L+L+ R Y +G +++DG + + L+ VPQ+ F+F+ +I +NI
Sbjct: 372 TGAGKTTLLRLLQREYDIKQGTIILDGRPIEHYTLDALKAAFGTVPQDHFLFSATIADNI 431
Query: 434 ALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMN 493
A AKP+AT E+ + +++A IHD I +GYDTVVGE+G+TLSGGQ+QR+++ARA+L N
Sbjct: 432 AFAKPDATISEIIQVSQLAHIHDDIIQFEQGYDTVVGERGVTLSGGQKQRVSIARALLAN 491
Query: 494 PKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVE 553
P I++LDD +S +DA+TE+ ++ L+ + KT +I + RLS +K D ++VM DG+IVE
Sbjct: 492 PNILILDDSLSAVDAKTEEAILSSLRAERKGKTTIITAHRLSAIKHADHILVMDDGRIVE 551
Query: 554 DGKPEELIKKGGIFSEM 570
G E L++ GG + M
Sbjct: 552 RGTHETLMEAGGWYRNM 568
>pir||T31073 multidrug resistance p-glycoprotein - nematode (Haemonchus
contortus) >gi|3057042|gb|AAC38987.1| (AF003908)
P-glycoprotein [Haemonchus contortus]
Length = 1275
Score = 265 bits (670), Expect = 1e-69
Identities = 164/498 (32%), Positives = 277/498 (54%), Gaps = 20/498 (4%)
Query: 88 AQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFL 147
A+ + LR +AI R ++ +FD +G L +R+T+D ER+ L ++ + + +
Sbjct: 140 AERITHKLRKIYLKAILRQQISWFDIQQTGNLTARLTDDLERVREGLGDKLSLFIQMVSA 199
Query: 148 IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIA-SIATGTI 206
+ + ++T+V ++ +V ++ + K+ ++ +T +A +IA T
Sbjct: 200 FVAGFCVGFAYSWSMTLVMMVVAPFIV-ISANWMSKIVATRTQVEQETYAVAGAIAEETF 258
Query: 207 AGIKTIKSLSVEENVQTKFS---QENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
+ I+T+ S+ + T+F ++ + + M + +G + ++ + F+
Sbjct: 259 SSIRTVHSICGHKRELTRFEAALEKGRQTGLVKYFYMGVGVGFGQ---MCTYVSYALAFW 315
Query: 264 YGGKAIIQN-TLTVGELVAFLTYMLTMMWPLRALGFTI---GDIQRSLAAASRLFDVIDS 319
YG II + L G + T +M ALG + I + A + VI+S
Sbjct: 316 YGSVLIINDPALDRGRI---FTVFFAVMSGSAALGTCLPHLNTISIARGAVRSVLSVINS 372
Query: 320 APKSIDPP--DAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPGEKVLITGPPG 375
PK IDP D + ++N RG I F++V +Y + RT +LKGVS +V G+K+ + G G
Sbjct: 373 RPK-IDPYSLDGIVLNNMRGSIRFKNVHFSYPSRRTLQILKGVSLQVSAGQKIALVGSSG 431
Query: 376 SGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIAL 435
GKS+ + L+ RFY PT+G+V ID ++V + + LR+ + V QEP +F+ ++ ENI +
Sbjct: 432 CGKSTNVNLLLRFYDPTRGKVTIDDIDVCDLNVQKLREQIGVVSQEPVLFDGTLFENIKM 491
Query: 436 AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPK 495
AT EEV+ A ++A DF LP+GY T VGE+G+ LSGGQ+QRIA+ARA++ NP+
Sbjct: 492 GYEQATMEEVQEACRVANAADFTKRLPEGYGTRVGERGVQLSGGQKQRIAIARAIIKNPR 551
Query: 496 IVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDG 555
I+LLD+ S LD E E + E L++ + +T +IV+ RLS ++ VD++ V K+G IVE G
Sbjct: 552 ILLLDEATSALDTEAESIVQEALEKAQKGRTTVIVAHRLSTIRNVDQIFVFKNGTIVEQG 611
Query: 556 KPEELIKKGGIFSEMMKA 573
EL+ K G+F EM +A
Sbjct: 612 THAELMNKRGVFFEMTQA 629
Score = 230 bits (581), Expect = 3e-59
Identities = 166/587 (28%), Positives = 300/587 (50%), Gaps = 27/587 (4%)
Query: 1 MRKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAID---KGVSTGAYK 57
+R + ++ + R +F++GL I+ VL I + V
Sbjct: 689 LRAKPTPMSKIFYFNRDKWGYFILGLIACIITGTVTPTFAVLYAQIIQVYSEPVDQMKGH 748
Query: 58 VAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTF 115
V G I+ +G+++ L + + LR +AF+ + R + F+D +
Sbjct: 749 VLFWCGAFIV-IGLVHAFAFFFSAICLGRCGEALTKKLRFEAFKNLLRQNVGFYDDIRHG 807
Query: 116 SGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVG 175
+G+L +R D + R++ R+ +L S+ II +L L ++ ++ + +++G
Sbjct: 808 TGKLCTRFATDAPNV-RYVFTRLPGVLSSVVTIIGALVIGFIFGWQLALILMVMVPLIIG 866
Query: 176 -----LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE 230
+ + K+R ++ + G +AS A + I+T+ +L+ +E + + +
Sbjct: 867 SGYFEMRMQFGKKMRDT--ELLEEAGKVASQA---VENIRTVHALNRQEQFHFMYCEYLK 921
Query: 231 ELYSLNV-KAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELV-AFLTYMLT 288
E Y N+ +A ++ + L+ + + F+ G + +++ ++ F +M
Sbjct: 922 EPYRENLCQAHTYGGVFAFSQSLLFFM-YAVAFWIGAIFVDNHSMQPIDVYRVFFAFMFC 980
Query: 289 MMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP-RGEIEFRDVWLT 347
F I D+ ++ AAS LF +I+ P ID ++ G I FR+V+
Sbjct: 981 GQMVGNISSF-IPDVVKARLAASLLFYLIEH-PSEIDNLSEDGVTKKISGHISFRNVYFN 1038
Query: 348 YHTGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAK 405
Y T R VL+G++ ++ PG V + G G GKS+++ L+ RFY KG + +DG N+
Sbjct: 1039 YPTRRQIRVLRGLNLEINPGTTVALVGQSGCGKSTVMALLERFYNQNKGVITVDGENIRN 1098
Query: 406 IKTENLRKIVAYVPQEPFIFNRSIRENIA--LAKPNATQEEVERAAKIAKIHDFIASLPK 463
+ NLR+ V V QEP +F+ +I ENI L P + E+V AAK+A IH+F+ LP+
Sbjct: 1099 MNIRNLREQVCIVSQEPTLFDCTIMENICYGLDDPKPSYEQVVAAAKMANIHNFVLGLPE 1158
Query: 464 GYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ 523
GYDT VGEKG LSGGQ+QRIA+ARA++ +P I+LLD+ S LD E+EK + + L+ Q
Sbjct: 1159 GYDTRVGEKGTQLSGGQKQRIAIARALIRDPPILLLDEATSALDTESEKIVQDALEVARQ 1218
Query: 524 DKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+T L+++ RLS ++ D ++++++GK + G E L+ K ++ +
Sbjct: 1219 GRTCLVIAHRLSTIQDSDVIVMIQEGKATDRGTHEHLLMKNDLYKRL 1265
>pir||F82198 probable toxin secretion transporter VC1446 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655946|gb|AAF94603.1| (AE004223) toxin secretion
transporter, putative [Vibrio cholerae]
Length = 721
Score = 265 bits (670), Expect = 1e-69
Identities = 161/534 (30%), Positives = 280/534 (52%), Gaps = 3/534 (0%)
Query: 38 IVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRM 97
+ P+L N IDK + + L +L + + +S + A L
Sbjct: 183 VSPMLFENVIDKVLVGRSLSSLHVLALAMLALAIAEPAYSYLRNTVFGHLASQVNAELSG 242
Query: 98 DAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVR 157
+R + + +F + +GQ+I+R+ + +I +FL+ MLL + + + L M
Sbjct: 243 RLYRHLVGLPLTYFKQRQTGQIIARV-REMAQIRQFLTGSTLMLLLDLIFVTVFLAVMFH 301
Query: 158 MNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSV 217
TLT + + ++ I L +R + + T + GI+TIK+ +
Sbjct: 302 YASTLTWLVIGSLVIYFVLWLIAGPLIRKKVESEYESDANATTFLTEAVTGIETIKTTAT 361
Query: 218 EENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVG 277
E ++ + + + + A K + G A LV L + + ++G A+++ +T G
Sbjct: 362 EHRFLEQWQRILSQQLNRSFDAQKSGLIAGQAIALVQKLTAALLLWWGVSAVLKGEITPG 421
Query: 278 ELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRG 337
+LVAF + P+ L D Q +L A R+ D++D P+ + G
Sbjct: 422 QLVAFNMLAGHVTQPVLRLAQIWQDFQHTLIALRRVGDILDE-PRENSKQGLASVPELDG 480
Query: 338 EIEFRDVWLTYHTGRT-VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEV 396
IEF ++ YH VL +S K+KPG+ + +TGP GSGKS++ +L+ R Y P G+V
Sbjct: 481 GIEFSNIRFRYHQDAPEVLANLSLKIKPGQFIGVTGPSGSGKSTLTRLLQRLYVPQHGQV 540
Query: 397 LIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHD 456
L+DG+++A +LR+ ++ V QE +F+ S+ +NI L KP A+ EE+ AA++A
Sbjct: 541 LVDGMDLAIADPVSLRRNMSVVLQESILFSGSVADNIRLCKPQASDEEIRHAAQLAGALA 600
Query: 457 FIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVE 516
FI LP G++ VGEKG LSGGQRQRIALARA+L+NP+I+LLD+ S LD +E ++
Sbjct: 601 FIEGLPHGFNQPVGEKGAALSGGQRQRIALARALLVNPRILLLDEATSALDYNSEASIMS 660
Query: 517 DLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++ EI + +T + ++ RL+ ++ D + V+ G++ E G EEL+ + G+++++
Sbjct: 661 NMDEICRGRTVISIAHRLNTIRHADNIFVLDKGQVAESGTHEELLAQQGLYAKL 714
>gb|AAA91200.1| (L76469) ABC-transporter [Gorilla gorilla]
Length = 747
Score = 265 bits (669), Expect = 1e-69
Identities = 168/575 (29%), Positives = 299/575 (51%), Gaps = 10/575 (1%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
N + RLL L + L L++L S +P D + G+ R L
Sbjct: 171 NPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTL 230
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V G + + +L+ + F A+ R E EFF + +G + SR+T
Sbjct: 231 MSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNITSRVTE 290
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT ++ LS + + L+ + + L M+ +++LTMV L+T+ ++ L +
Sbjct: 291 DTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQ 350
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
+ ++R + +A ++ + T++S + EE KF ++ +E+ +LN K A+
Sbjct: 351 LLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAV 410
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ L + Y GG+ + ++ G LV F+ Y + + L +Q+
Sbjct: 411 NSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQK 470
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVK 363
++ ++ ++F+ +D P+ P + + G ++F+DV Y VL+G++F +
Sbjct: 471 AVGSSEKIFEYLDRTPRC-PPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLH 529
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
PGE + GP GSGKS++ L+ Y+PT G++L+DG + + + L + VA V QEP
Sbjct: 530 PGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQ 589
Query: 424 IFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+F RS++ENIA KP T EE+ AA H FI+ L +GYDT VGE G LSGGQ
Sbjct: 590 VFGRSLQENIAYGLTQKP--TMEEITAAAVKCGAHSFISGLRQGYDTEVGEAGSQLSGGQ 647
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVK 538
RQ +ALARA++ P +++LDD S LDA ++ ++ + L E + ++ L+++Q LSLV+
Sbjct: 648 RQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVE 707
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++ ++ G I E G ++L++K G + M++A
Sbjct: 708 QADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQA 742
>emb|CAA62898.1| (X91786) ATP-binding cassette transporter A [Staphylococcus aureus]
Length = 575
Score = 265 bits (669), Expect = 1e-69
Identities = 166/539 (30%), Positives = 290/539 (53%), Gaps = 18/539 (3%)
Query: 31 LMSYTNSIVPVLIRNAIDKGVSTGAYKVA-IRYGLLILLVG--VLNGVFSLAGRYLLVKA 87
L S + +VP+ +DK + V+ I + L+ L G V+N + S G YLL K
Sbjct: 30 LGSLSGLLVPLFTGRIVDK------FSVSHINWNLIALFGGIFVINALLSGLGLYLLSKI 83
Query: 88 AQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFL 147
+ +Y +R + I + +M FFDK SGQL+SR+T+DT+ I F+S ++ LL SI
Sbjct: 84 GEKIIYAIRSVLWEHIIQLKMPFFDKNESGQLMSRLTDDTKVINEFISQKLPNLLPSIVT 143
Query: 148 IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIA 207
++ SL + ++ +T++ ITI I V + ++ I + + + + +
Sbjct: 144 LVGSLIMLFILDWKMTLLTFITIPIFVLIMIPLGRIMQKISTSTQSEIANFSGLLGRVLT 203
Query: 208 GIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGK 267
++ +K + E + E+Y L +K KI A+ +V+ L ++ + +G
Sbjct: 204 EMRLVKISNTERLELDNAHKNLNEIYKLGLKQAKIAAVVQPISGIVMLLTIAIILGFGAL 263
Query: 268 AIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPP 327
I +T G L+A + Y++ + PL L + D ++++ A+SR+++++ + I+P
Sbjct: 264 EIATGAITAGTLIAMIFYVIQLSMPLINLSTLVTDYKKAVGASSRIYEIMQ---EPIEPT 320
Query: 328 DAVEISN----PRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILK 383
+A+E S G + F V Y + +L VSF++ G+ GP GSGKS+I
Sbjct: 321 EALEDSENVLIDDGVLSFEHVDFKYDV-KKILDDVSFQIPQGQVSAFVGPSGSGKSTIFN 379
Query: 384 LIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-KPNATQ 442
LI R Y+ G++ +V I R+ + YV Q + + +IR+NI + +
Sbjct: 380 LIERMYEIESGDIKYGLESVYDIPLSKWRRKIGYVMQSNSMMSGTIRDNILYGINRHVSD 439
Query: 443 EEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
EE+ AK+A HDFI +GYDT+VGE+G+ LSGGQRQRI +AR+ + NP I+LLD+
Sbjct: 440 EELINYAKLANCHDFIMQFDEGYDTLVGERGLKLSGGQRQRIDIARSFVKNPDILLLDEA 499
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI 561
+NLD+E+E K+ E L+ +++ +T ++++ RLS +K ++I + G++ G EL+
Sbjct: 500 TANLDSESELKIQEALETLMEGRTTIVIANRLSTIKKAGQIIFLDKGQVTGKGTHSELM 558
>gb|AAB88659.1| (U62935) multidrug resistance protein 2 [Aspergillus fumigatus]
>gi|2673957|gb|AAB88660.1| (U62936) multidrug resistance
protein 2 [Aspergillus fumigatus]
Length = 791
Score = 265 bits (669), Expect = 1e-69
Identities = 178/587 (30%), Positives = 305/587 (51%), Gaps = 22/587 (3%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
+ ++ RLL R A + +++ S +P I +D
Sbjct: 161 KAGFKEIWRLLLIARPEAKKLALAFLFLLVSSGITMSIPFSIGKIMDTSTKATTEGGNEL 220
Query: 62 YGL-LILLVGVLNGVFSLA-----GRYLLVK-AAQYAVYYLRMDAFRAIQRHEMEFFDKT 114
+GL L + G L G+ +L GR ++++ + V LR FR + EFFD
Sbjct: 221 FGLSLPMFYGALAGILTLGAAANYGRIIILRIVGERIVARLRSKLFRQTFVQDAEFFDAN 280
Query: 115 FSGQLISRITNDT----ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITI 170
G LISR+++DT + IT+ LS +R + + Y ++++ +++AL+
Sbjct: 281 RVGDLISRLSSDTIIVGKSITQNLSDGLRAAVSGAAGFGLMAYVSLKLS---SILALLLP 337
Query: 171 AIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE 230
I +G Y +R + +I+ G + IA + +KT +S + E +++ +
Sbjct: 338 PIGLGA-FFYGRAIRNLSRQIQRNLGTLTKIAEERLGNVKTSQSFAGEVLEVRRYNNQVR 396
Query: 231 ELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM 290
+++ L K I+A + ++ + + + Y GG + +T+GEL +FL Y
Sbjct: 397 KIFELGKKESLISATFFSSTGFAGNMTILALLYVGGGMVQSGAITIGELTSFLMYTAYAG 456
Query: 291 WPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT 350
+ L ++ + + AASRLF++ D P +I P ++++ RG I F +V +Y T
Sbjct: 457 SSMFGLSSFYSELMKGVGAASRLFELQDRQP-TISPTKGEKVASARGPIRFENVTFSYPT 515
Query: 351 GRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
V + ++F++ G V I GP G GKS+I ++ RFY PT+G VLI G ++ +
Sbjct: 516 RPAVPIFRDLNFEIPQGTNVAIVGPSGGGKSTIASILLRFYSPTEGRVLIGGKDITHMNA 575
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTV 468
++LR+ + V QEP +F+ +I ENIA KP A + E+ AA+ A FI+ P G DT
Sbjct: 576 KSLRRKIGIVSQEPVLFSGTIAENIAYGKPQAKRSEIVAAARKANC-QFISDFPDGLDTQ 634
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ-DKTA 527
VG +G LSGGQ+QRIA+ARA++ +P I++LD+ S LDAE+E + L +L+ + T
Sbjct: 635 VGPRGAQLSGGQKQRIAIARALIKDPDILILDEATSALDAESETLVNSALTALLRGNNTT 694
Query: 528 LIVSQRLSLVKLVDRVIVM-KDGKIVEDGKPEEL-IKKGGIFSEMMK 572
+ ++ RLS +K D +IV+ DG++ E G EEL + G F+++M+
Sbjct: 695 ISIAHRLSTIKRSDTIIVLGPDGRVAEQGSYEELSARPDGAFTKLME 741
>pir||T13416 hypothetical protein 171D11.2 - fruit fly (Drosophila melanogaster)
>gi|3766257|emb|CAA15633.1| (AL009147)
/prediction=(method:""genscan"", version:""1.0"",
score:""184.75"")~/prediction=(method:""genefinder"",
version:""084"")~/motif=(desc:""ATP/GTP-binding site
motif A (P-loop)"", dbase:""PROSITE"", acc:""PS00017"",
method:""ppsearch"")~/motif=>
Length = 609
Score = 264 bits (668), Expect = 2e-69
Identities = 174/597 (29%), Positives = 295/597 (49%), Gaps = 31/597 (5%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAID-----KGVSTGAYKVAI 60
+Q RLLS + G+ +++ S VP+ + ID G+ + A
Sbjct: 4 SQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAKLG 63
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
Y +L+ + VL G + A +L AA V LR +R++ E+ +FD +G+LI
Sbjct: 64 EYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELI 123
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
+R++NDT + LS V L S+ +I + M+ + L V+ + + + G+ Y
Sbjct: 124 NRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVY 183
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
VR I + I A +KT+K+ E+ F + +E + K
Sbjct: 184 GRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKET 243
Query: 241 KITALYGNA----------------PFLVLGLA----MSTMFYYGGKAIIQNTLTVGELV 280
+ A++ P G + ++ YYGG ++Q++LT+G L
Sbjct: 244 RARAIFFGLVRPKGKVLRKIIKICYPLFQTGFCGNFIIISVLYYGGTLVLQDSLTIGALT 303
Query: 281 AFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIE 340
AF+ Y + + L + + + A+ R+++++D V + P GE+
Sbjct: 304 AFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIPIDKGVVPLEKPVGEVG 363
Query: 341 FRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLI 398
F++V+ T+ T VL S + PG + G GSGK++I L+ R Y P G V +
Sbjct: 364 FQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHL 423
Query: 399 DGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIAL-AKPNATQ--EEVERAAKIAKIH 455
DG+++ + + LR + V QEP +F+ SIRENI A P T E +++ + A +
Sbjct: 424 DGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIEDANVS 483
Query: 456 DFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLV 515
F LP G DT+VG++G+ LSGGQ+QR+A+ARA++ NP I++LD+ S LDA +E +
Sbjct: 484 QFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQ 543
Query: 516 EDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMM 571
L ++Q +T L ++ RLS ++ D++ V+ DGKIVE G EL+ + G+F E++
Sbjct: 544 NALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELV 600
>gb|AAF71763.1|AF263912_2 (AF263912) NysG [Streptomyces noursei]
Length = 605
Score = 264 bits (668), Expect = 2e-69
Identities = 160/575 (27%), Positives = 289/575 (49%), Gaps = 11/575 (1%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAID----------KGVSTGAYKVA 59
RL+ LR H + + + + N+ P+L+ D G + G A
Sbjct: 19 RLVGLLRPHRRSVALAVSMGVGGIVLNAFGPLLLGRVTDLIADGVLGGVPGPAPGIDFAA 78
Query: 60 IRYGLLILL-VGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQ 118
I LL+LL + V+ +F LA L+ A ++ LR DA + R + FD+ +G+
Sbjct: 79 IGRLLLVLLALYVVASLFMLAQGRLVASAVWRTIHELRRDAREKLTRLPLRHFDRQPAGE 138
Query: 119 LISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNT 178
L+SR TND + + + L + L+ SIF ++ L M+ ++ +L +V L+++ + +
Sbjct: 139 LLSRTTNDIDNLQQTLQQTLAELITSIFSLLTMLVLMLVISPSLAVVMLLSVPVSALIAA 198
Query: 179 TYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+ + +P Y G + + G IK + +F N+ +Y K
Sbjct: 199 RISKRAQPHYAAQWSANGTLNAHVEEVCTGHALIKGFDRRAAAEERFDACNDAVYRAAAK 258
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
A + V L + G +I TLT+G++ AF+ Y P+ +
Sbjct: 259 AQFASGAMEPVMMFVANLGYVLVAVIGAWKVINGTLTLGDVQAFILYARQFSQPIVEIAS 318
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGV 358
G +Q +A+A R+F ++D+ ++ DP + G +EF DV Y +++ +
Sbjct: 319 VAGRLQSGIASAQRVFTLLDAPEQAPDPLRPGTPARAEGRVEFTDVSFRYSPDTPLIENL 378
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
S V+PG V I GP G+GK+++ L+ RFY+P G +L+DG + A + ++LR V
Sbjct: 379 SLTVEPGSTVAIVGPTGAGKTTLGNLLMRFYEPDSGRILLDGTDTATMTRDDLRSRFGLV 438
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
Q+ ++F +I ENIA P A + ++E AA+ FI +LP+GYDTV+ ++ T+S
Sbjct: 439 LQDTWLFGGTIAENIAYGAPGACRADIEEAARATCADRFIRTLPQGYDTVLDDESGTVSA 498
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
G++Q + +ARA L P +++LD+ S++D TE + + + +T+ +++ RLS ++
Sbjct: 499 GEKQLLTVARAFLARPAVLVLDEATSSVDTRTEVLIQRAMNSLRAGRTSFVIAHRLSTIR 558
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
D ++VM G+IVE G ++L+ G+++ + A
Sbjct: 559 DADLIVVMDAGRIVEQGTHDQLLCAQGLYARLHAA 593
>gb|AAF45509.1| (AE003417) EG:171D11.2 gene product [Drosophila melanogaster]
Length = 643
Score = 264 bits (668), Expect = 2e-69
Identities = 174/597 (29%), Positives = 295/597 (49%), Gaps = 31/597 (5%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAID-----KGVSTGAYKVAI 60
+Q RLLS + G+ +++ S VP+ + ID G+ + A
Sbjct: 38 SQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAKLG 97
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
Y +L+ + VL G + A +L AA V LR +R++ E+ +FD +G+LI
Sbjct: 98 EYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELI 157
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
+R++NDT + LS V L S+ +I + M+ + L V+ + + + G+ Y
Sbjct: 158 NRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVY 217
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
VR I + I A +KT+K+ E+ F + +E + K
Sbjct: 218 GRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKET 277
Query: 241 KITALYGNA----------------PFLVLGLA----MSTMFYYGGKAIIQNTLTVGELV 280
+ A++ P G + ++ YYGG ++Q++LT+G L
Sbjct: 278 RARAIFFGLVRPKGKVLRKIIKICYPLFQTGFCGNFIIISVLYYGGTLVLQDSLTIGALT 337
Query: 281 AFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIE 340
AF+ Y + + L + + + A+ R+++++D V + P GE+
Sbjct: 338 AFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIPIDKGVVPLEKPVGEVG 397
Query: 341 FRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLI 398
F++V+ T+ T VL S + PG + G GSGK++I L+ R Y P G V +
Sbjct: 398 FQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHL 457
Query: 399 DGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIAL-AKPNATQ--EEVERAAKIAKIH 455
DG+++ + + LR + V QEP +F+ SIRENI A P T E +++ + A +
Sbjct: 458 DGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIEDANVS 517
Query: 456 DFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLV 515
F LP G DT+VG++G+ LSGGQ+QR+A+ARA++ NP I++LD+ S LDA +E +
Sbjct: 518 QFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQ 577
Query: 516 EDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMM 571
L ++Q +T L ++ RLS ++ D++ V+ DGKIVE G EL+ + G+F E++
Sbjct: 578 NALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELV 634
>emb|CAA71282.1| (Y10233) Tap1 protein [Rattus norvegicus]
Length = 725
Score = 264 bits (667), Expect = 2e-69
Identities = 169/576 (29%), Positives = 295/576 (50%), Gaps = 12/576 (2%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
+ L R+L +L + L L+IL +P D + R L
Sbjct: 148 DMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFARNMWL 207
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + AG + + + + FRA+ E FF K +G + SR+T
Sbjct: 208 MCILTIASSALEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTE 267
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT + +S ++ + L+ + + L +M+ + LT+V L+++ ++ L +
Sbjct: 268 DTSNVCESISDKLNLFLWYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPRRLGKVYQ 327
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK--IT 243
+ K++ +A ++ + T++S + EE KF Q+ EE+ LN K +T
Sbjct: 328 SLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKPLNKKEALAYVT 387
Query: 244 ALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
++ + V G+ + + Y GG+ +++ ++ G LV+F+ Y L + L
Sbjct: 388 EVWTMS---VSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAVEVLLSIYPS 444
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSF 360
+Q+S+ A+ ++F+ +D P S + N +G ++F+DV Y H VL+G++F
Sbjct: 445 MQKSVGASEKIFEYLDRTPCSPLSGSLAPL-NMKGLVKFQDVSFAYPNHPNVQVLQGLTF 503
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+ PG+ + GP GSGKS++ L+ Y+PT G+VL+DG + + L VA V Q
Sbjct: 504 TLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLHTQVAAVGQ 563
Query: 421 EPFIFNRSIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G LSGG
Sbjct: 564 EPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGG 623
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLV 537
QRQ +ALARA++ P++++LDD S LDA + ++ L E + +T L+++Q+LSL
Sbjct: 624 QRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLLITQQLSLT 683
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ ++ +K+G + E G +L++KGG + M++A
Sbjct: 684 ERAHHILFLKEGSVCEQGTHLQLMEKGGCYRSMVEA 719
>emb|CAA40742.1| (X57523) mtp1 [Rattus norvegicus]
Length = 740
Score = 263 bits (666), Expect = 3e-69
Identities = 169/576 (29%), Positives = 296/576 (51%), Gaps = 12/576 (2%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
+ L R+L +L + L L+IL +P D + R L
Sbjct: 163 DMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFARNMWL 222
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V AG + + + + FRA+ E FF K +G + SR+T
Sbjct: 223 MCILTIASTVLEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTE 282
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT + +S ++ + L+ + + L +M+ + LT+V L+++ ++ L +
Sbjct: 283 DTSNVCESISDKLNLFLWYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPRRLGKVYQ 342
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK--IT 243
+ K++ +A ++ + T++S + EE KF Q+ EE+ LN K +T
Sbjct: 343 SLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKPLNKKEALAYVT 402
Query: 244 ALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
++ + V G+ + + Y GG+ +++ ++ G LV+F+ Y L + L
Sbjct: 403 EVWTMS---VSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAVEVLLSIYPS 459
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSF 360
+Q+S+ A+ ++F+ +D P S + N +G ++F+DV Y H VL+G++F
Sbjct: 460 MQKSVGASEKIFEYLDRTPCSPLSGSLAPL-NMKGLVKFQDVSFAYPNHPNVQVLQGLTF 518
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+ PG+ + GP GSGKS++ L+ Y+PT G+VL+DG + + L VA V Q
Sbjct: 519 TLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLHTQVAAVGQ 578
Query: 421 EPFIFNRSIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G LSGG
Sbjct: 579 EPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGG 638
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLV 537
QRQ +ALARA++ P++++LDD S LDA + ++ L E + +T L+++Q+LSL
Sbjct: 639 QRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLLITQQLSLA 698
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ ++ +K+G + E G +L+++GG + M++A
Sbjct: 699 ERAHHILFLKEGSVCEQGTHLQLMERGGCYRSMVEA 734
>sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) >gi|111520|pir||S13426
multidrug resistance protein homolog - rat
>gi|1771566|emb|CAA71280.1| (Y10231) Tap1 protein
[Rattus norvegicus] >gi|227426|prf||1703417A mtp1
protein [Rattus norvegicus]
Length = 725
Score = 263 bits (666), Expect = 3e-69
Identities = 169/576 (29%), Positives = 296/576 (51%), Gaps = 12/576 (2%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
+ L R+L +L + L L+IL +P D + R L
Sbjct: 148 DMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFARNMWL 207
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + V AG + + + + FRA+ E FF K +G + SR+T
Sbjct: 208 MCILTIASTVLEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTE 267
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT + +S ++ + L+ + + L +M+ + LT+V L+++ ++ L +
Sbjct: 268 DTSNVCESISDKLNLFLWYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPRRLGKVYQ 327
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK--IT 243
+ K++ +A ++ + T++S + EE KF Q+ EE+ LN K +T
Sbjct: 328 SLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKPLNKKEALAYVT 387
Query: 244 ALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
++ + V G+ + + Y GG+ +++ ++ G LV+F+ Y L + L
Sbjct: 388 EVWTMS---VSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAVEVLLSIYPS 444
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSF 360
+Q+S+ A+ ++F+ +D P S + N +G ++F+DV Y H VL+G++F
Sbjct: 445 MQKSVGASEKIFEYLDRTPCSPLSGSLAPL-NMKGLVKFQDVSFAYPNHPNVQVLQGLTF 503
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+ PG+ + GP GSGKS++ L+ Y+PT G+VL+DG + + L VA V Q
Sbjct: 504 TLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLHTQVAAVGQ 563
Query: 421 EPFIFNRSIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G LSGG
Sbjct: 564 EPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGG 623
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLV 537
QRQ +ALARA++ P++++LDD S LDA + ++ L E + +T L+++Q+LSL
Sbjct: 624 QRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLLITQQLSLA 683
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ ++ +K+G + E G +L+++GG + M++A
Sbjct: 684 ERAHHILFLKEGSVCEQGTHLQLMERGGCYRSMVEA 719
>pir||D70031 ABC transporter (ATP-binding protein) homolog yvcC - Bacillus
subtilis >gi|1945644|emb|CAB08051.1| (Z94043)
hypothetical protein [Bacillus subtilis]
>gi|2635995|emb|CAB15487.1| (Z99121) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 589
Score = 263 bits (666), Expect = 3e-69
Identities = 161/545 (29%), Positives = 289/545 (52%), Gaps = 6/545 (1%)
Query: 26 LFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLV 85
L L ++ + + ++P+L + +D G S + GL+ L+ V G+ + A Y L
Sbjct: 33 LALSVVTTLVSLLIPLLTKQLVD-GFSMSNLS-GTQIGLIALVFFVQAGLSAYA-TYALN 89
Query: 86 KAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSI 145
Q + LR ++ + + + +FD SG+ +SR+TNDT + ++ + + I
Sbjct: 90 YNGQKIISGLRELLWKKLIKLPVSYFDTNASGETVSRVTNDTMVVKELITTHISGFITGI 149
Query: 146 FLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGT 205
+I SL + MN LT++ L+ + + + K+ I + + +T +
Sbjct: 150 ISVIGSLTILFIMNWKLTLLVLVVVPLAALILVPIGRKMFSISRETQDETARFTGLLNQI 209
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+ I+ +K+ + E+ + L+ L V+ K+ +L G LVL A+ + YG
Sbjct: 210 LPEIRLVKASNAEDVEYGRGKMGISSLFKLGVREAKVQSLVGPLISLVLMAALVAVIGYG 269
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
G + LT G LVAF+ Y+ ++ P+ + +Q+S+ A R+ +++ A + D
Sbjct: 270 GMQVSSGELTAGALVAFILYLFQIIMPMGQITTFFTQLQKSIGATERMIEIL--AEEEED 327
Query: 326 PPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLI 385
+I N I+ V Y + +LK VS ++ G+ I GP G GK+++ KL+
Sbjct: 328 TVTGKQIENAHLPIQLDRVSFGYKPDQLILKEVSAVIEAGKVTAIVGPSGGGKTTLFKLL 387
Query: 386 ARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-KPNATQEE 444
RFY PT G + + V E+ R+ + YV QE + + +IRENI + + T E
Sbjct: 388 ERFYSPTAGTIRLGDEPVDTYSLESWREHIGYVSQESPLMSGTIRENICYGLERDVTDAE 447
Query: 445 VERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVS 504
+E+AA++A +FI LP +DT VGE+GI LSGGQRQRIA+ARA+L NP I++LD+ S
Sbjct: 448 IEKAAEMAYALNFIKELPNQFDTEVGERGIMLSGGQRQRIAIARALLRNPSILMLDEATS 507
Query: 505 NLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKG 564
+LD+++EK + + L+ +++ +T ++++ RLS V D+++ ++ G+I G EL+
Sbjct: 508 SLDSQSEKSVQQALEVLMEGRTTIVIAHRLSTVVDADQLLFVEKGEITGRGTHHELMASH 567
Query: 565 GIFSE 569
G++ +
Sbjct: 568 GLYRD 572
>emb|CAA71281.1| (Y10232) Tap1 protein [Rattus norvegicus]
Length = 725
Score = 263 bits (666), Expect = 3e-69
Identities = 168/576 (29%), Positives = 296/576 (51%), Gaps = 12/576 (2%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
+ L R+L +L + L L+IL +P D + R L
Sbjct: 148 DMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFARNMWL 207
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + AG + + + + FRA+ E FF K +G + SR+T
Sbjct: 208 MCILTIASTALEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTE 267
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT + +S ++ + L+ + + L +M+ + LT+V L+++ ++ L +
Sbjct: 268 DTSNVCESISDKLNLFLWYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPRRLGKVYQ 327
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK--IT 243
+ K++ +A ++ + T++S + EE KF Q+ EE+ LN K +T
Sbjct: 328 SLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKPLNKKEALAYVT 387
Query: 244 ALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
++ + V G+ + + Y GG+ +++ ++ G LV+F+ Y L + L
Sbjct: 388 EVWTMS---VSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAVEVLLSIYPS 444
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSF 360
+Q+S+ A+ ++F+ +D P S + N +G ++F+DV Y H VL+G++F
Sbjct: 445 MQKSVGASEKIFEYLDRTPCSPLSGSLAPL-NMKGLVKFQDVSFAYPNHPNVQVLQGLTF 503
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+ PG+ + GP GSGKS++ L+ Y+PT+G+VL+DG + + L VA V Q
Sbjct: 504 TLYPGKVTALVGPNGSGKSTVAALLQNLYQPTRGKVLLDGEPLVQYDHHYLHTQVAAVGQ 563
Query: 421 EPFIFNRSIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G LSGG
Sbjct: 564 EPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGG 623
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLV 537
QRQ +ALARA++ P++++LDD S LDA + ++ L E + +T L+++Q+LSL
Sbjct: 624 QRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLLITQQLSLA 683
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ ++ +K+G + E G +L+++GG + M++A
Sbjct: 684 ERAHHILFLKEGSVCEQGTHLQLMERGGCYRSMVEA 719
>pir||G71731 mitochondrial transporter atm1 precursor (atm1) RP205 - Rickettsia
prowazekii >gi|3860769|emb|CAA14670.1| (AJ235270)
MITOCHONDRIAL TRANSPORTER ATM1 PRECURSOR (atm1)
[Rickettsia prowazekii]
Length = 609
Score = 262 bits (663), Expect = 7e-69
Identities = 171/579 (29%), Positives = 298/579 (50%), Gaps = 23/579 (3%)
Query: 6 NQLIRLLSYLRGH----AVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
N LL+YL + + L +++ N VP++ + ID G++ +++
Sbjct: 18 NAFYLLLTYLWSKDFDIRLRIVTSLICLVIAKVINIFVPIVYKYIID-GLNQNL-SLSVL 75
Query: 62 YGLLILLVG--VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
G++I G +L +FS + K A + ++ F+ + M F +G L
Sbjct: 76 IGVIIGYGGTKILAQIFSELRNIIFSKVGCQATRLVALNVFKHMHNLSMRFHITRKTGGL 135
Query: 120 ---ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYM--VRMNITLTMVALITIAIVV 174
I R T E + R+ F + I L+I L+Y + +TL + ++ + +
Sbjct: 136 SRSIERGTKGIEAVLRYSLFNIFPTSLEIILVIGILWYFHGIWFAVTLLITMIVYVCYTL 195
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
++T R ++ + A ++ +T+K + EE KF N+ L +
Sbjct: 196 LISTWRISFAR----EMNQSDNTANNRAIDSLLNFETVKYFNNEEYEAIKF---NDALQA 248
Query: 235 LNVKAMKIT---ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMW 291
A KIT ++ +++ L + ++ AI QN + VG+L+ Y+ +
Sbjct: 249 YEKSATKITNSLSILNIGQDVIISLGLVSLMILSVNAINQNKMMVGDLIMVNAYLFQLSI 308
Query: 292 PLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG 351
PL LGF +I+ +L +F ++D + D DA E+ + ++ F +V Y+
Sbjct: 309 PLSILGFAYREIKNALVNMEDMFKLLDIPAEIQDSVDAKELIISKCKVSFNNVSFAYNKE 368
Query: 352 RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
RT+L ++F ++ G+ + + G G+GKS+I +L+ RFY G ++ID ++ ++K +L
Sbjct: 369 RTILHNITFTIESGKTIAVVGSSGAGKSTISRLLFRFYDINSGSIIIDNQDIREVKQGSL 428
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGE 471
RK + VPQ+ +FN +I NIA A+ +EV A+K A IH+FI+ LP+GY T VGE
Sbjct: 429 RKSIGIVPQDTVLFNDTIYYNIAYGNNAASYDEVIAASKNAHIHEFISVLPEGYATQVGE 488
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
+G+ LSGG++QRIA+AR +L NP I + D+ S+LD +TEK + LKEI + T LI++
Sbjct: 489 RGLKLSGGEKQRIAIARTILKNPSIYVFDEATSSLDTKTEKLIQASLKEISANHTTLIIA 548
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
RLS + D +IV+ +G IVE G + L+K G ++E+
Sbjct: 549 HRLSTIVDADEIIVLDNGYIVERGNHKTLLKNQGYYAEL 587
>pir||I84547 mdl protein - Escherichia coli >gi|146801|gb|AAC36870.1| (L08627)
putative [Escherichia coli] >gi|739997|prf||2004284A mdl
gene [Escherichia coli]
Length = 1143
Score = 262 bits (662), Expect = 9e-69
Identities = 158/518 (30%), Positives = 287/518 (54%), Gaps = 19/518 (3%)
Query: 38 IVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRM 97
+V +++ ++ +TG + I +LI +V L R LL A+ LR
Sbjct: 9 VVGIVVDGVTEQHFTTGQILMWIATMVLIAVVVYL---LRYVWRVLLFGASYQLAVELRE 65
Query: 98 DAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFL---IIISLYY 154
D +R + R EF+ + +G L++R TND +R+ V L+ S+ + ++I +
Sbjct: 66 DYYRQLSRQHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMACAVLIMMST 125
Query: 155 MVRMNITL-TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGT---IAGIK 210
+ +TL +++ + +AI++ N ++++ + +S+ T + I+
Sbjct: 126 QISWQLTLFSLLPMPVMAIMIKRNGD------ALHERFKLAQAAFSSLNDRTQESLTSIR 179
Query: 211 TIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAII 270
IK+ +E+ F+ + E+ ++ +I A + ++ +G+A G ++
Sbjct: 180 MIKAFGLEDRQSALFAADAEDTGKKKLRVARIDARFDPTIYIAIGMANLLAIGGGSWMVV 239
Query: 271 QNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAV 330
Q +LT+G+L +F+ Y+ M+WP+ AL + ++R AA SR+ ++ P D + V
Sbjct: 240 QGSLTLGQLTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAERPVVNDGSEPV 299
Query: 331 EISNPRGEIEFRDVWLTY-HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFY 389
RGE++ TY T L+ V+F +KPG+ + I GP GSGKS++L LI R +
Sbjct: 300 P--EGRGELDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPNGSGKSTLLSLIQRHF 357
Query: 390 KPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAA 449
+ G++ + + K++ ++ R +A V Q PF+F+ ++ NIAL PNATQ+E+E A
Sbjct: 358 DVSPGDIRFHDIPLTKLQLDSWRTGLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVA 417
Query: 450 KIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAE 509
++A +HD I LP+GYDT VGE+G+ LSGGQ+QRI++ARA+L+N +I++LDD +S +D
Sbjct: 418 RLASVHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGR 477
Query: 510 TEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMK 547
TE +++ +L++ Q +T +I + RLS + +IVM+
Sbjct: 478 TEHQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQ 515
Score = 185 bits (464), Expect = 1e-45
Identities = 149/583 (25%), Positives = 271/583 (45%), Gaps = 23/583 (3%)
Query: 3 KSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIV----PVLIRNAIDKGVSTGAYKV 58
+S +QL L L + + L + +LM + + P+LI ID V+ +
Sbjct: 561 RSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPLLISYFIDNMVAKNNLPL 620
Query: 59 AIRYGLLILLVGVLNGVFSL--AGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
+ GL VG+ L A L +AA V LR D A R + FD
Sbjct: 621 KVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPV 680
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGL 176
GQ+ISR+TNDTE I V +L S L+ L M ++ + +VA++ +V+ +
Sbjct: 681 GQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVV 740
Query: 177 NTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLN 236
Y PI ++R I I G+ I+ + + + + Y
Sbjct: 741 MVIYQRYSTPIVRRVRAYLADINDGFKQIINGMSVIQQFRQQARFGERMGEASRSHYMAR 800
Query: 237 VKAMKITALYGN------APFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM 290
++ +++ + ++ GL M F G T+ VG L AF++Y+ +
Sbjct: 801 MQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSASG------TIEVGVLYAFISYLGRLN 854
Query: 291 WPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT 350
PL L +Q+++ A R+F+++D + D S G IE +V Y
Sbjct: 855 EPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDRPFTS---GTIEVDNVSFAYRD 911
Query: 351 GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTEN 410
VL ++ V V + G GSGKS++ L+ +Y T+GE+ +DG ++ + +
Sbjct: 912 DNLVLNNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSL-SHT 970
Query: 411 LRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVG 470
+ VA V Q+P + + N+ L + + ++E V +A + ++ D S+ G T +G
Sbjct: 971 RGQGVAMVQQDPVVLADTFLANVTLGR-DISEERVWQALETVQLADVARSMSDGIYTPLG 1029
Query: 471 EKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIV 530
E+G LS GQ+Q +ALAR ++ P+I++LD+ +++D+ TE+ + L + + T +++
Sbjct: 1030 EQGNNLSVGQKQLLALARVLVETPQILILDEATASIDSGTEQAIQHALAAVREHTTLVVI 1089
Query: 531 SQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ RLS + ++V+ G+ VE G ++L++ + +++ A
Sbjct: 1090 AHRLSTIVDAATILVLHRGQAVEQGTHQQLLRPRDVLADVSTA 1132
>emb|CAA71279.1| (Y10230) Tap1 protein [Rattus norvegicus]
>gi|1771572|emb|CAA71283.1| (Y10234) Tap1 protein
[Rattus norvegicus]
Length = 725
Score = 262 bits (662), Expect = 9e-69
Identities = 169/576 (29%), Positives = 295/576 (50%), Gaps = 12/576 (2%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
+ L R+L +L + L L+IL +P D + R L
Sbjct: 148 DMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFARNMWL 207
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ V + AG + + + + FRA+ E FF K +G + SR+T
Sbjct: 208 MCILTVASTALEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTE 267
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT + +S ++ + L+ + + L +M+ + LT+V L+++ ++ L +
Sbjct: 268 DTSNVCESISDKLNLFLWYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPRRLGKVYQ 327
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK--IT 243
+ K++ +A ++ + T++S + EE KF Q+ EE+ LN K +T
Sbjct: 328 SLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKPLNKKEALAYVT 387
Query: 244 ALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
++ + V G+ + + Y GG+ +++ ++ G LV+F+ Y L + L
Sbjct: 388 EVWTMS---VSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAVEVLLSIYPS 444
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSF 360
+Q+S+ A+ ++F+ +D P S + N +G ++F+DV Y H VL+G++F
Sbjct: 445 MQKSVGASEKIFEYLDRTPCSPLSGSLAPL-NMKGLVKFQDVSFAYPNHPNVQVLQGLTF 503
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+ PG+ + GP GSGKS++ L+ Y+PT G+VL+DG + + L VA V Q
Sbjct: 504 TLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGELLVQYDHHYLHTQVAAVGQ 563
Query: 421 EPFIFNRSIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G LSGG
Sbjct: 564 EPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGG 623
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLV 537
QRQ +ALARA++ P++++LDD S LDA + ++ L E + +T L+++Q+LSL
Sbjct: 624 QRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLLITQQLSLA 683
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ ++ +K+G + E G +L+++GG + M++A
Sbjct: 684 ERAHHILFLKEGSVCEQGTHLQLMERGGCYRSMVEA 719
>emb|CAA71284.1| (Y10235) Tap1 protein [Rattus norvegicus]
Length = 725
Score = 261 bits (661), Expect = 1e-68
Identities = 168/576 (29%), Positives = 295/576 (51%), Gaps = 12/576 (2%)
Query: 6 NQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLL 65
+ L R+L +L + L L+IL +P D + R L
Sbjct: 148 DMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFARNMWL 207
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+ ++ + + AG + + + + FRA+ E FF K +G + SR+T
Sbjct: 208 MCILTIASTALEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTE 267
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DT + +S ++ + L+ + + L +M+ + LT+V L+++ ++ L +
Sbjct: 268 DTSNVCESISDKLNLFLWYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPRRLGKVYQ 327
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK--IT 243
+ K++ +A ++ + T++S + EE KF Q+ EE+ LN K +T
Sbjct: 328 SLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKPLNKKEALAYVT 387
Query: 244 ALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
++ + V G+ + + Y GG+ +++ ++ G LV+F+ Y L + L
Sbjct: 388 EVWTMS---VSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAVEVLLSIYPS 444
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSF 360
+Q+S+ A+ ++F+ +D P S + N +G ++F+DV Y H VL+G++F
Sbjct: 445 MQKSVGASEKIFEYLDRTPCSPLSGSLAPL-NMKGLVKFQDVSFAYPNHPNVQVLQGLTF 503
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+ PG+ + GP GSGKS++ L+ Y+PT G+VL+DG + + L VA V Q
Sbjct: 504 TLYPGKVTSLVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLHTQVAAVGQ 563
Query: 421 EPFIFNRSIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G LSGG
Sbjct: 564 EPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGG 623
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLV 537
QRQ +ALARA++ P++++LDD S LDA + ++ L E + +T L+++Q+LSL
Sbjct: 624 QRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLLITQQLSLA 683
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ ++ +K+G + E G +L+++GG + M++A
Sbjct: 684 ERAHHILFLKEGSVCEQGTHLQLMERGGCYRSMVEA 719
>pir||B83507 probable ATP-binding/permease fusion ABC transporter PA1113
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9947031|gb|AAG04502.1|AE004541_7 (AE004541) probable
ATP-binding/permease fusion ABC transporter [Pseudomonas
aeruginosa]
Length = 588
Score = 261 bits (661), Expect = 1e-68
Identities = 167/544 (30%), Positives = 290/544 (52%), Gaps = 11/544 (2%)
Query: 43 IRNAIDKGVSTGAYKVAIRYGLL--ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAF 100
IR +D+G T + ++ RY LL +L++G+ G F YL+ + V +R F
Sbjct: 48 IRLLVDQGFLTASPELLNRYILLFFVLVLGLAVGTF--VRFYLVSWIGERFVADIRKRVF 105
Query: 101 RAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNI 160
+ F++ S ++ SR+T DT + + + M L + +++ + M N
Sbjct: 106 DHLIELHPGFYETNRSSEIQSRLTADTTLLQTVIGSSLSMALRNALMLVGGVLLMFVTNA 165
Query: 161 TLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEEN 220
LT + ++ + +V+ + +VR + + + + + S T+ IKT+++ + +
Sbjct: 166 KLTSIVVLALPLVIAPILLFGRRVRSLSRESQDRVADVGSYVGETLGQIKTVQAYNHQAQ 225
Query: 221 VQTKFSQENEELYSLNVKAMKITA-LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGEL 279
+ +F+ E + K + A L LVLG A+ M + GG+ +I +++ GEL
Sbjct: 226 DRQRFAGTVERAFDTARKRIAQRAWLITVVIVLVLG-AVGIMLWVGGRDVIAGSISAGEL 284
Query: 280 VAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPR--G 337
AF+ Y L + L IG++QR+ AA R+ +++ A I PP R G
Sbjct: 285 AAFVFYSLIVGMAFGTLSEVIGELQRAAGAAERIAELL-RARSEIRPPAQPRKLAARVSG 343
Query: 338 EIEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGE 395
IE + V Y T + +S V+PGE + + GP G+GKS++ L+ RF+ P +G
Sbjct: 344 RIELQAVRFAYPTRPEHWAIDDISLAVEPGETLALVGPSGAGKSTLFDLLLRFFDPQQGR 403
Query: 396 VLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIH 455
+L+DG + ++ +LR+ A V Q P +F S+ ENI +P+A+ EVE AA+ A H
Sbjct: 404 LLLDGQPIVELDPADLRRSFALVSQNPALFFGSVEENIRYGRPHASAAEVEAAARAAHAH 463
Query: 456 DFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLV 515
+FI LP+GY T +GE GI LSGGQRQR+A+ARA+L++ ++LLD+ S LDAE+E +
Sbjct: 464 EFILGLPQGYATHLGEGGIGLSGGQRQRLAIARALLVDAPVLLLDEATSALDAESEHLIQ 523
Query: 516 EDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGG 575
+ L ++ +T L+++ RL+ V+ DR+ V+ G++V G LI + +++ + +
Sbjct: 524 QALPGLMSGRTTLVIAHRLATVQSADRIAVIDQGRLVAIGSHARLIAENPLYARLAELQF 583
Query: 576 VYGG 579
GG
Sbjct: 584 AAGG 587
>sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA >gi|1073873|pir||H64045
probable ABC-type transport protein msbA - Haemophilus
influenzae (strain Rd KW20) >gi|1573008|gb|AAC21738.1|
(U32691) ABC transporter, ATP-binding protein (msbA)
[Haemophilus influenzae Rd]
Length = 587
Score = 261 bits (660), Expect = 2e-68
Identities = 160/564 (28%), Positives = 290/564 (51%), Gaps = 5/564 (0%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
RL ++ ++ ++ + +S + L++ +D G + +++ +
Sbjct: 19 RLWPMIKPFKAGLIVSGVALVFNALADSGLIYLLKPLLDDGFGKANHSFLKMMAFVVVGM 78
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
+L G+ + Y L + V +R F+ + + FFD+ +G+L+SRIT D++
Sbjct: 79 IILRGITNFISNYCLAWVSGKVVMTMRRRLFKHLMFMPVSFFDQNSTGRLLSRITYDSQM 138
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
I S + ++ II M + LT+V I I+ L + R +
Sbjct: 139 IASSSSGSLITIVREGAYIISLFAVMFYTSWELTIVLFIIGPIIAVLIRLVSKIFRRLSK 198
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
++ G + S + G K + S + + F+ + ++ ++K + ++
Sbjct: 199 NLQDSMGELTSATEQMLKGHKVVLSFGGQHVEEVHFNHVSNDMRRKSMKMVTANSISDPV 258
Query: 250 PFLVLGLAMSTMFYYGGKAII-QNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLA 308
++ LA++T+ Y +I ++ L+ G + ML MM PL++L Q +A
Sbjct: 259 VQVIASLALATVLYLATTPLIAEDNLSAGSFTVVFSSMLAMMRPLKSLTAVNAQFQSGMA 318
Query: 309 AASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH-TGRTVLKGVSFKVKPGEK 367
A LF ++D P+ D A + +GE+EF++V Y L +SF V G+
Sbjct: 319 ACQTLFAILDLEPEKDD--GAYKAEPAKGELEFKNVSFAYQGKDELALNNISFSVPAGKT 376
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
V + G GSGKS+I L+ RFY +GE+L+DGVN+ + NLR+ A V Q+ +FN
Sbjct: 377 VALVGRSGSGKSTIANLVTRFYDIEQGEILLDGVNIQDYRLSNLRENCAVVSQQVHLFND 436
Query: 428 SIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIAL 486
+I NIA A + ++EE+ AAK A +FI LP+ +DTV+GE G +LSGGQRQR+A+
Sbjct: 437 TIANNIAYAAQDKYSREEIIAAAKAAYALEFIEKLPQVFDTVIGENGTSLSGGQRQRLAI 496
Query: 487 ARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVM 546
ARA+L N +++LD+ S LD E+E+ + L+E+ +D+T ++++ RLS ++ D ++V+
Sbjct: 497 ARALLRNSPVLILDEATSALDTESERAIQSALEELKKDRTVVVIAHRLSTIENADEILVI 556
Query: 547 KDGKIVEDGKPEELIKKGGIFSEM 570
G+I E G + L+++ G + ++
Sbjct: 557 DHGEIRERGNHKTLLEQNGAYKQL 580
>gi|6324985 ATP-binding cassette (ABC) transporter family member; Mdl2p
[Saccharomyces cerevisiae]
>gi|2506122|sp|P33311|MDL2_YEAST ATP-DEPENDENT PERMEASE
MDL2 >gi|2132334|pir||S65303 MDL2 protein - yeast
(Saccharomyces cerevisiae) >gi|1370557|emb|CAA98006.1|
(Z73626) ORF YPL270w [Saccharomyces cerevisiae]
Length = 820
Score = 261 bits (660), Expect = 2e-68
Identities = 161/504 (31%), Positives = 274/504 (53%), Gaps = 8/504 (1%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKA-AQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISR 122
L V +L G + GR++L++ ++ V LR + + + EFFD G LISR
Sbjct: 218 LSFFTVALLIGCAANFGRFILLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISR 277
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
+ +D ++R ++ +V + ++ ++ + M ++ L+++ L V+ + +
Sbjct: 278 LGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGK 337
Query: 183 KVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKI 242
++R ++ TG + +A ++GIKT++S E N ++++ +++ + A
Sbjct: 338 QIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFT 397
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
A + L+ L+ T+ YG ++Q+ L++G+L AF+ Y + L +
Sbjct: 398 NAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSE 457
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSF 360
I + AASRLF++ D P SI P + RG IEF+DV +Y T +V K ++F
Sbjct: 458 IMQGAGAASRLFELTDRKP-SISPTVGHKYKPDRGVIEFKDVSFSYPTRPSVQIFKNLNF 516
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
K+ PG V I GP G GKS+I L+ R+Y PT G + ID +++K+ ++LR+ + V Q
Sbjct: 517 KIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQ 576
Query: 421 EPFIFNRSIRENIALAKP-NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP + + +IR+NI T+EE+ AK H+FI P YDTV+G G LSGG
Sbjct: 577 EPVLMSGTIRDNITYGLTYTPTKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGG 636
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS--QRLSLV 537
Q+QRIA+ARA++ P I++LD+ S LD E+E + ++++ K+ IVS RLS +
Sbjct: 637 QKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTI 696
Query: 538 KLVDRVIVM-KDGKIVEDGKPEEL 560
+ + VIV+ DG +VE GK +EL
Sbjct: 697 RRSENVIVLGHDGSVVEMGKFKEL 720
>pir||S77459 ABC-type transport protein slr1149 - Synechocystis sp. (strain PCC
6803) >gi|1652384|dbj|BAA17306.1| (D90905) ABC
transporter [Synechocystis sp.]
Length = 601
Score = 261 bits (660), Expect = 2e-68
Identities = 166/593 (27%), Positives = 310/593 (51%), Gaps = 46/593 (7%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAI-----------------DKG 50
L+RLL Y++ + L L+I ++++ ++ P++I A+ D+
Sbjct: 17 LLRLLPYVKRYPKELAAALVLLIPVAFSGAVQPLIIGQAVSLLREEPAWGFLDAMPLDRA 76
Query: 51 VSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEF 110
+ T +A+ + +L +G+ +++ K Q +R D F + + F
Sbjct: 77 LHTLVIILAVTIVIRLLFLGLQG--------FIVQKMGQEITADVRQDLFEHVTSLSVNF 128
Query: 111 FDKTFSGQLISRITNDTERITR-FLSFRVRML--LYSIFLIIISLYYMVRMNITLTMVAL 167
F +T G+L++RIT+D E + F S + ++ + SI II+++++ V+ + L +V +
Sbjct: 129 FHRTPVGRLVTRITSDVEALGEVFASGAIGVVSDIVSILAIIVTIFW-VQWQLALLLVGM 187
Query: 168 ITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQ 227
+ V L + + R + R + + S +AGI ++ EE F +
Sbjct: 188 LVPVTV--LIIYFQQQYRKANYQAREELSRLNSQLQENVAGINVVQLFRREELNSRSFRR 245
Query: 228 ENEELYSLNVKAMKITALYGNAPFLVLG----LAMSTMFYYGGKAIIQNTLTVGELVAFL 283
NE+ +A+ T + +A L +A++ + GG I+++ L G L AF+
Sbjct: 246 VNEKYR----RAVDKTIFHDSAVSATLEWISLVAIAGVLGLGGWLILRDNLEFGVLAAFI 301
Query: 284 TYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPP--DAVEISNP----RG 337
Y + PLR Q A R+ ++++ + D +EI+ G
Sbjct: 302 LYGQRLFNPLRQFADKFTMFQSGFTAIERIGELMEEPVEIKDQAVITPIEINGALRGSHG 361
Query: 338 EIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVL 397
EI F +VW Y VLK ++F +KPGEKV + GP G+GKSSI++L+ R + P++G +L
Sbjct: 362 EICFENVWFGYKPDEYVLKNLNFTIKPGEKVALVGPTGAGKSSIIRLLCRLHDPSRGRIL 421
Query: 398 IDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDF 457
+DG+++ ++ + LR+ + + Q+ F+F ++ NI L + + EEV+RAA++ +
Sbjct: 422 VDGIDIRELSQQQLRRFIGVILQDSFLFAGDVKRNITLGEEYSL-EEVQRAAQLTSVDRL 480
Query: 458 IASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVED 517
I LP+GY T + E+G LSGGQ+Q +A AR + P ++++D+ ++LD TE +
Sbjct: 481 IEELPQGYHTQLRERGSNLSGGQKQLLAFARVAIREPYVLVMDEATASLDVRTEADIQAA 540
Query: 518 LKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
L +LQD+T++I++ RLS ++ VDR+ V+K G+IVE G ++L+ G+++ +
Sbjct: 541 LLHLLQDRTSIIIAHRLSTIRNVDRIFVLKHGEIVETGNHDQLLDLKGLYASL 593
>pir||T31077 probable ABC-transporter TycD - Brevibacillus brevis
>gi|2623774|gb|AAC45931.1| (AF004835) putative
ABC-transporter TycD [Brevibacillus brevis]
Length = 595
Score = 261 bits (660), Expect = 2e-68
Identities = 169/565 (29%), Positives = 306/565 (53%), Gaps = 13/565 (2%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVG 70
+LS+++ + +I +F +L++ + ++ VLI+ ++ T + ++ L+I +
Sbjct: 21 VLSFVKPYRTWVVICIFASLLVAVADILMGVLIQRMVEH---TNDFDKLVQIALIIFCLT 77
Query: 71 VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERI 130
++ + Y + + A+ L+ +++ M D+ SG L+SR+T+D + +
Sbjct: 78 IVGFLAKYFITYSAARFSARAMRDLKNKMAAHLEKVPMSTMDQYHSGDLVSRLTSDAQIL 137
Query: 131 TRFLSFRVRMLLYS--IFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
FL L Y +F ++L + + + VA++ IAIV+ + ++
Sbjct: 138 QSFLQQHFFQLFYLPVVFAGALTLLLSINWKLIIFSVAILPIAIVI--TGRMSRPLQTYA 195
Query: 189 DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGN 248
++++ G ++A T++GI +K+ +E + K++ +++ + A K A +
Sbjct: 196 ERMQEHLGQANTVAQDTLSGIHMVKAFQLENVMYRKYAAGMKQVLKNGILAEKKRA-WMT 254
Query: 249 APFLVLGLAMSTMFY-YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL 307
AP ++L A F YGG I L++G LV F + ++ PL +Q +
Sbjct: 255 APGILLFSAPILFFVAYGGYLIQTGELSLGSLVIFSYLLHFIIEPLSLAPVLFAQVQETS 314
Query: 308 AAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEK 367
AA RL D+ P + A+ I +EF +V Y + +L+ VSF + P +
Sbjct: 315 GAAKRLQDIF-LQPVEENGRTAIPIDPAAVPVEFENVSFAYEKTK-ILENVSFVLPPNKT 372
Query: 368 VLITGPPGSGKSSILKLIARFYK--PTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
V + G GSGKS+ILKL+ FY+ P G + + G ++ T +R ++ V Q+ +F
Sbjct: 373 VALVGASGSGKSTILKLLCGFYRIEPGNGCMKVFGHSLNDWNTAEMRHYLSLVSQDTTLF 432
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
SI ENI+ + +AT++E+ AAK A HDFI LP+GY+T VGE+G LSGGQ+QRIA
Sbjct: 433 PVSIAENISYGRVHATRDEIIAAAKAANAHDFILELPQGYETKVGERGSRLSGGQKQRIA 492
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+ARA+L + I+LLD+P S LD E+E + E L+ +++++T L+++ RLS +K D V+V
Sbjct: 493 IARALLKDAPILLLDEPTSALDTESEALVQEALENVMRNRTVLVIAHRLSTIKDADEVLV 552
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEM 570
++ G+IVE G EL+ +GG+++ +
Sbjct: 553 LEQGQIVERGTHYELLAQGGVYTRL 577
>gb|AAC02113.1| (AF045016) multidrug resistance p-glycoprotein [Canis familiaris]
Length = 1280
Score = 261 bits (659), Expect = 2e-68
Identities = 173/554 (31%), Positives = 294/554 (52%), Gaps = 27/554 (4%)
Query: 28 LIILMSYTNSIVPVLIRNAIDKGVSTGAYKVA-IRYGLLILLVGVLNGVFSLAGRYLLVK 86
+II S TN+ + N +++ ++T AY + I G+L+ ++ AGR +L
Sbjct: 91 VIINESITNNTQHFI--NHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQILK- 147
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
+R F AI R E+ +FD G+L +R+T+D +I + +V M SI
Sbjct: 148 --------IRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKVGMFFQSIA 199
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 200 TFFTGFIVGFTPGWKLTLV-ILAISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEV 258
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + A FL++ + + F+YG
Sbjct: 259 LAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYG 318
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP---- 321
++ + T+G+++ +L + + +I + AA +F +ID+ P
Sbjct: 319 TSLVLSSEYTIGQVLTVFFSVLIGAFSIGQASPSIEAFANARGAAYEIFKIIDNKPSIDS 378
Query: 322 --KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
KS PD N +G +EF++V +Y + + V LKG++ KV+ G+ V + G G G
Sbjct: 379 YSKSGHKPD-----NIKGNLEFKNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCG 433
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAK 437
KS+ ++L+ R Y PT G V IDG ++ I +LR+I V QEP +F +I ENI +
Sbjct: 434 KSTTVQLMQRLYDPTDGMVCIDGQDIRTINVRHLREITGVVSQEPVLFATTIAENIRYGR 493
Query: 438 PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+
Sbjct: 494 ENVTMDEIEKAVKEANAYDFIMKLPNKFDTLVGERGARLSGGQKQRIAIARALVRNPKIL 553
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
LLD+ S LD E+E + L + + +T ++++ RLS V+ D + DG IVE G
Sbjct: 554 LLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNH 613
Query: 558 EELIKKGGIFSEMM 571
+EL+K+ GI+ +++
Sbjct: 614 DELMKEKGIYFKLV 627
Score = 238 bits (601), Expect = 1e-61
Identities = 158/568 (27%), Positives = 297/568 (51%), Gaps = 23/568 (4%)
Query: 21 HFLIGLFLIILMSYTNSIVPVLIRNAI-----DKGVSTGAYKVAIRYGLLILLVGVLNGV 75
+F++G+F I+ ++ I D+ T + + +L L++G+++ +
Sbjct: 711 YFVVGIFCAIINGGLQPAFSIIFSRIIGIFTRDEDPETKRQNSNM-FSVLFLVLGIISFI 769
Query: 76 FSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITRF 133
+ KA + LR FR++ R ++ +FD K +G L +R+ ND ++
Sbjct: 770 TFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGA 829
Query: 134 LSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ R+ ++ +I IIISL Y +TL ++A++ I + G+ + + + D
Sbjct: 830 IGSRLAVITQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKD 887
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
K + IAT I +T+ SL+ E+ + ++Q + Y +++ I + +
Sbjct: 888 KKELEGA--GKIATEAIENFRTVVSLTREQKFEYMYAQSLQVPYRNSLRKAHIFGVSFSI 945
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
++ + + F +G + + +++ + ++ + + D ++ +
Sbjct: 946 TQAMMYFSYAGCFRFGAYLVANEFMNFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVS 1005
Query: 310 ASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPG 365
A+ + +I+ +P ID P ++ + G + F +V Y T VL+G+S +VK G
Sbjct: 1006 AAHVIMIIEKSPL-IDSYSPHGLKPNTLEGNVTFNEVVFNYPTRPDIPVLQGLSLEVKKG 1064
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
+ + + G G GKS++++L+ RFY P G VLIDG + + + LR + V QEP +F
Sbjct: 1065 QTLALVGSSGCGKSTVVQLLERFYDPLAGSVLIDGKEIKHLNVQWLRAHLGIVSQEPILF 1124
Query: 426 NRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+ SI ENIA + + EE+ +AAK A IH FI +LP+ Y+T VG+KG LSGGQ+QR
Sbjct: 1125 DCSIAENIAYGDNSRVVSHEEIMQAAKEANIHHFIETLPEKYNTRVGDKGTQLSGGQKQR 1184
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
IA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++++ RLS ++ D +
Sbjct: 1185 IAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLI 1244
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEMM 571
+V ++GK+ E G ++L+ + GI+ M+
Sbjct: 1245 VVFQNGKVKEHGTHQQLLAQKGIYFSMI 1272
>gb|AAA20682.1| (L16959) Mdl2p [Saccharomyces cerevisiae]
Length = 812
Score = 260 bits (658), Expect = 3e-68
Identities = 161/504 (31%), Positives = 274/504 (53%), Gaps = 8/504 (1%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKA-AQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISR 122
L V +L G + GR++L++ ++ V LR + + + EFFD G LISR
Sbjct: 218 LSFFTVALLIGCAANFGRFILLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISR 277
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
+ +D ++R ++ +V + ++ ++ + M ++ L+++ L V+ + +
Sbjct: 278 LGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCCLSPQLSILLLFFTPPVLFSASVFGK 337
Query: 183 KVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKI 242
++R ++ TG + +A ++GIKT++S E N ++++ +++ + A
Sbjct: 338 QIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFT 397
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
A + L+ L+ T+ YG ++Q+ L++G+L AF+ Y + L +
Sbjct: 398 NAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSE 457
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSF 360
I + AASRLF++ D P SI P + RG IEF+DV +Y T +V K ++F
Sbjct: 458 IMQGAGAASRLFELTDRKP-SISPTVGHKYKPDRGVIEFKDVSFSYPTRPSVQIFKNLNF 516
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
K+ PG V I GP G GKS+I L+ R+Y PT G + ID +++K+ ++LR+ + V Q
Sbjct: 517 KIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQ 576
Query: 421 EPFIFNRSIRENIALAKP-NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
EP + + +IR+NI T+EE+ AK H+FI P YDTV+G G LSGG
Sbjct: 577 EPVLMSGTIRDNITYGLTYTPTKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGG 636
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS--QRLSLV 537
Q+QRIA+ARA++ P I++LD+ S LD E+E + ++++ K+ IVS RLS +
Sbjct: 637 QKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTI 696
Query: 538 KLVDRVIVM-KDGKIVEDGKPEEL 560
+ + VIV+ DG +VE GK +EL
Sbjct: 697 RRSENVIVLGHDGSVVEMGKFKEL 720
>gb|AAB41965.1| (U60021) TAP1-f [Mus musculus]
Length = 724
Score = 260 bits (657), Expect = 3e-68
Identities = 172/579 (29%), Positives = 296/579 (50%), Gaps = 10/579 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
R + + L R+L +L + L L+IL +P D + R
Sbjct: 143 RDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAIPFFTGRITDWILQDKTVPSFTR 202
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
L+ ++ + + A + + ++ + FRA+ R E FF K +G + S
Sbjct: 203 NIWLMSILTIASTALEFASDGIYNITMGHMHGHVHREVFRAVLRQETGFFLKNPAGSITS 262
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+T DT + +S + +LL+ + + L +M + LT+V LI + ++ L
Sbjct: 263 RVTEDTANVCESISGTLSLLLWYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLG 322
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK-AM 240
+ + K++ +A ++ + T++S + EE KF Q+ EE+ +LN K A+
Sbjct: 323 KVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEAL 382
Query: 241 KITALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
A V G+ + + Y GG+ +I+ T++ G LV+F+ Y L ++ L
Sbjct: 383 AYVAEVWTTS--VSGMLLKVGILYLGGQLVIRGTVSSGNLVSFVLYQLQFTQAVQVLLSL 440
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKG 357
+Q+++ ++ ++F+ +D P S ++ SN +G +EF+DV Y V L+G
Sbjct: 441 YPSMQKAVGSSEKIFEYLDRTPCS-PLSGSLAPSNMKGLVEFQDVSFAYPNQPKVQVLQG 499
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
++F + PG + GP GSGKS++ L+ Y+PT G++L+DG + + L VA
Sbjct: 500 LTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQRLVQYDHHYLHTQVAA 559
Query: 418 VPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
V QEP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G L
Sbjct: 560 VGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDFISGFPQGYDTEVGETGNQL 619
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRL 534
SGGQRQ +ALARA++ P +++LDD S LDA + ++ L E + +T L+++Q+L
Sbjct: 620 SGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQL 679
Query: 535 SLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
SL + ++ +++G + E G +L+K+GG + M++A
Sbjct: 680 SLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEA 718
>gb|AAB41966.1| (U60022) TAP1-k [Mus musculus]
Length = 724
Score = 260 bits (657), Expect = 3e-68
Identities = 172/579 (29%), Positives = 296/579 (50%), Gaps = 10/579 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
R + + L R+L +L + L L+IL +P D + R
Sbjct: 143 RDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAIPFFTGRITDWILQDKTVPSFTR 202
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
L+ ++ + + A + + ++ + FRA+ R E FF K +G + S
Sbjct: 203 NIWLMSILTIASTALEFASDGIYNITMGHMHGHVHREVFRAVLRQETGFFLKNPAGSITS 262
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+T DT + +S + +LL+ + + L +M + LT+V LI + ++ L
Sbjct: 263 RVTEDTANVCESISDTLSLLLWYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLG 322
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK-AM 240
+ + K++ +A ++ + T++S + EE KF Q+ EE+ +LN K A+
Sbjct: 323 KVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEAL 382
Query: 241 KITALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
A V G+ + + Y GG+ +I+ T++ G LV+F+ Y L ++ L
Sbjct: 383 AYVAEVWTTS--VSGMLLKVGILYLGGQLVIRGTVSSGNLVSFVLYQLQFTHAVQVLLSL 440
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKG 357
+Q+++ ++ ++F+ +D P S ++ SN +G +EF+DV Y V L+G
Sbjct: 441 YPSMQKAVGSSEKIFEYLDRTPCS-PLSGSLAPSNMKGLVEFQDVSFAYPNQPKVQVLQG 499
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
++F + PG + GP GSGKS++ L+ Y+PT G++L+DG + + L VA
Sbjct: 500 LTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQRLVQYDHHYLHTQVAA 559
Query: 418 VPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
V QEP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G L
Sbjct: 560 VGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDFISGFPQGYDTEVGETGNQL 619
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRL 534
SGGQRQ +ALARA++ P +++LDD S LDA + ++ L E + +T L+++Q+L
Sbjct: 620 SGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQL 679
Query: 535 SLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
SL + ++ +++G + E G +L+K+GG + M++A
Sbjct: 680 SLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEA 718
>gb|AAB58721.2| (AF001154) TAP1 [Mesocricetus auratus]
Length = 803
Score = 260 bits (657), Expect = 3e-68
Identities = 167/570 (29%), Positives = 294/570 (51%), Gaps = 7/570 (1%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
RLL +L + L ++IL +P D + IR L+ ++
Sbjct: 191 RLLGFLGSEKRRLHLVLVILILSCLGEMAIPFFTGRITDWILQDKTASSFIRNIWLMSIL 250
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
+ + AG + + + FRA+ E FF + +G + SR+T DT +
Sbjct: 251 TLASTALEFAGDGIYKTTMGHMHSRAHGEVFRAVLHQETGFFLQNPAGSITSRVTEDTSK 310
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ +S ++ +L++ + + L +M +++LT+V L + ++ L + +
Sbjct: 311 VCESISDKLNLLMWYLGRGLCLLAFMFWGSVSLTLVTLAALPLLFLLPQKLGKVYKSLEA 370
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
+++ +A ++ + T++S + EE KF Q+ EE+ +L+ K +
Sbjct: 371 RVQESLAESTQVAIEALSAMPTVRSFANEEGEAQKFRQKLEEMKALSKKEALAYVVEVWT 430
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
+ L + Y GG+ +++ ++ G+LV+F+ Y L ++AL +QR++ +
Sbjct: 431 TSISGMLLKVGILYMGGQLVVRGAVSSGDLVSFVLYQLQFTTAVQALLSYYPWMQRAVGS 490
Query: 310 ASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEK 367
+ ++F+ +D +P S + N +G +EF+DV Y H VL+G++F + PG+
Sbjct: 491 SEKIFEYLDRSPCSPLSGSLAPL-NMKGLVEFQDVSFAYPNHPDDQVLQGLTFTLHPGKV 549
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
+ GP GSGKS++ L+ Y+PT G++L+DG + + L VA V QEP +F R
Sbjct: 550 TALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQPLVQYDHHYLHTQVAAVQQEPLLFGR 609
Query: 428 SIRENIALAKP-NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIAL 486
S RENIA N T EE+ AK + HDFI LP+GYDT VGE G LSGGQRQ +AL
Sbjct: 610 SFRENIAYGLTRNPTMEEITAVAKESGAHDFIPGLPQGYDTEVGESGNQLSGGQRQAVAL 669
Query: 487 ARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI--LQDKTALIVSQRLSLVKLVDRVI 544
ARA++ P++++LDD S LDA + ++ L E T L+++Q+LSLV+ ++
Sbjct: 670 ARALIRKPRLLILDDATSALDANNQLRVQRLLYENPGPASPTVLLITQQLSLVEQAHHIL 729
Query: 545 VMKDGKIVEDGKPEELIKK-GGIFSEMMKA 573
+++G + E G +L++K GG + M++A
Sbjct: 730 FLEEGSVCEQGTHLQLMEKTGGRYRAMVEA 759
>gb|AAD53035.1|AF115538_1 (AF115538) TAP2B protein [Oncorhynchus mykiss]
Length = 723
Score = 259 bits (656), Expect = 4e-68
Identities = 144/509 (28%), Positives = 280/509 (54%), Gaps = 11/509 (2%)
Query: 71 VLNGVFSLAGRY-------LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
+L G++SL + L + A +++ F A+ + E+ FF+ +G + SR+
Sbjct: 205 ILMGLYSLGSSFSAGCRGGLFMCAINSFTCRMKVKLFGALVKQEIGFFETIKTGDITSRL 264
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
+ DT + R ++ V +LL ++ + M+ ++ LT++ L+ + L + +
Sbjct: 265 STDTTLMGRAVALNVNVLLRTLIKTVGMSSLMMSLSWKLTLLMLMETPVTGLLQSVHDNY 324
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
+ + +++ A T+ GI+T++S E++ +++ + ++L + +
Sbjct: 325 YQRLSKEVQDSIARANEAAGETVGGIRTVRSFKTEQHEAGRYNDRLMDTHNLKTRRDTVM 384
Query: 244 ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
A+Y L + M YYG I + ++ G LV+F+ Y + +R L + GD+
Sbjct: 385 AVYLLLRRLTAVVMQVAMLYYGRLFIQRGQMSTGNLVSFILYQSDLADNIRTLIYIFGDM 444
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVLKGVSFK 361
S+ AA ++F+ +D P+ + ++ G ++F ++ +Y T R VL+G S +
Sbjct: 445 LNSVGAAGKVFEYLDREPQ-VSTKGTLQPETLTGHVQFHNLSFSYPTRQERKVLQGFSLE 503
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
++PG+ + GP G GKS+ + L+ RFY+P +GE+L+DG+ + + L + +A V QE
Sbjct: 504 LRPGQLTALVGPSGGGKSTCVSLLERFYQPQQGEILLDGLPLQSYQHHYLHRKIAMVGQE 563
Query: 422 PFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQR 481
P +F+ S+++NIA + + E V+ AA+ A H FI+ L KGYDT VGE+G LSGG++
Sbjct: 564 PVLFSGSVKDNIAYGLADCSLERVQEAARRANAHSFISQLEKGYDTDVGERGGQLSGGEK 623
Query: 482 QRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVD 541
QRIA+ARA++ P++++LD+ S LD E+E +V++ +T L+++ RL ++ D
Sbjct: 624 QRIAIARALIREPQVLILDEVTSALDTESE-HMVQEALASCPSQTLLVIAHRLKTIERAD 682
Query: 542 RVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++I++ G + E G +EL+ + G + ++
Sbjct: 683 QIILIDQGTVQEQGTHQELMDRKGSYYKL 711
>gb|AAB58723.2| (AF001156) TAP1 [Mesocricetus auratus]
Length = 803
Score = 259 bits (656), Expect = 4e-68
Identities = 167/570 (29%), Positives = 294/570 (51%), Gaps = 7/570 (1%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
RLL +L + L ++IL +P D + IR L+ ++
Sbjct: 191 RLLGFLGSEKRRLHLVLVILILSCLGEMAIPFFTGRITDWILQDKTASSFIRNIWLMSIL 250
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
+ + AG + + + FRA+ E FF + +G + SR+T DT +
Sbjct: 251 TLASTALEFAGDGIYNTTMGHMHSRAHGEVFRAVLHQETGFFLQNQAGSITSRVTEDTSK 310
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ +S ++ +L++ + + L +M +++LT+V L + ++ L + +
Sbjct: 311 VCESISDKLNLLMWYLGRGLCLLAFMFWGSVSLTLVTLAALPLLFLLPQKLGKVYKSLEA 370
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
+++ +A ++ + T++S + EE KF Q+ EE+ +L+ K +
Sbjct: 371 RVQESLAESTQVAIEALSAMPTVRSFANEEGEAQKFRQKLEEMKALSKKEALAYVVEVWT 430
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
+ L + Y GG+ +++ ++ G+LV+F+ Y L ++AL +QR++ +
Sbjct: 431 TSISGMLLKVGILYMGGQLVVRGAVSSGDLVSFVLYQLQFTTAVQALLSYYPWMQRAVGS 490
Query: 310 ASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEK 367
+ ++F+ +D +P S + N +G +EF+DV Y H VL+G++F + PG+
Sbjct: 491 SEKIFEYLDRSPCSPLSGSLAPL-NMKGLVEFQDVSFAYPNHPDVQVLQGLTFTLHPGKV 549
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
+ GP GSGKS++ L+ Y+PT G++L+DG + + L VA V QEP +F R
Sbjct: 550 TALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQPLVQYDHHYLHTQVAAVQQEPLLFGR 609
Query: 428 SIRENIALAKP-NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIAL 486
S RENIA N T EE+ AK + HDFI LP+GYDT VGE G LSGGQRQ +AL
Sbjct: 610 SFRENIAYGLTRNPTMEEITAVAKESGAHDFIPGLPQGYDTEVGESGNQLSGGQRQAVAL 669
Query: 487 ARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI--LQDKTALIVSQRLSLVKLVDRVI 544
ARA++ P++++LDD S LDA + ++ L E T L+++Q+LSLV+ ++
Sbjct: 670 ARALIRKPRLLILDDATSALDANNQLRVQRLLYENPGPASPTVLLITQQLSLVEQAHHIL 729
Query: 545 VMKDGKIVEDGKPEELIKK-GGIFSEMMKA 573
+++G + E G +L++K GG + M++A
Sbjct: 730 FLEEGSVCEQGTHLQLMEKTGGRYRAMVEA 759
>pir||S75806 hemolysin secretion protein hlyB - Synechocystis sp. (strain PCC
6803) >gi|1653351|dbj|BAA18265.1| (D90913) HlyB family
[Synechocystis sp.]
Length = 1011
Score = 259 bits (655), Expect = 6e-68
Identities = 154/556 (27%), Positives = 285/556 (50%), Gaps = 5/556 (0%)
Query: 24 IGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYL 83
+ F + L N P++I+ IDK + + G+ ++ + + + S YL
Sbjct: 457 VASFFVQLFGLAN---PLMIQIIIDKVIVQNSKDTLQVLGIALVSIAIFEALLSTLRTYL 513
Query: 84 LVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLY 143
V L + + R + +F+ G++ +R+ N+ E I +FL+ ++
Sbjct: 514 FVDTTNRIDMSLGSEIIDHLLRLPLRYFENRPVGEISTRV-NELENIRQFLTGTALTVVL 572
Query: 144 SIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIAT 203
++ + M+ + LT VAL + I V L ++ +R + S
Sbjct: 573 DSVFSVVYIVVMIIYSPLLTAVALGIVPIFVILTLVFSPLIRRQLRLKAERNAQTQSYLV 632
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
++GI+T+K+ ++E + ++ + + + L ++ + L+ + +
Sbjct: 633 EVMSGIQTVKAQNIELRSRWQWQDKYSRYVGAGFNTVITSTLASSSSHFLNQLSGLLVLW 692
Query: 264 YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKS 323
G ++ LT+G+L+AF + P+ L + Q + + RL D++D+ +S
Sbjct: 693 VGASLVLDGDLTLGQLIAFRIIAGYVTSPILRLTQLWQNFQETALSLERLADIVDTPQES 752
Query: 324 IDPPDAVEISNPRGEIEFRDVWLTYHT-GRTVLKGVSFKVKPGEKVLITGPPGSGKSSIL 382
+ + GE++F +V + G L ++ PG V + G G+GKS++
Sbjct: 753 ERDRQNIPMPEIAGEVKFENVSFRFKKQGPLQLNNINLSFPPGTFVALVGQSGAGKSTLT 812
Query: 383 KLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQ 442
KL++R Y+P G +L+DG+++ K++ +LR+ V VPQE +F +++ENIAL P+AT
Sbjct: 813 KLLSRLYEPEGGRILVDGLDIGKVELYSLRRQVGVVPQETLLFEGTVQENIALTNPDATT 872
Query: 443 EEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
E++ AAK+A H+FI +LP GY+T VGE+G TLSGGQRQRIA+AR++L P+I++LD+
Sbjct: 873 EQIISAAKVASAHEFIMTLPNGYNTRVGERGATLSGGQRQRIAIARSVLQRPRILVLDEA 932
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK 562
S LD TE+++ +L + +D T ++ RLS V+ D +++M G +VE G +EL+
Sbjct: 933 TSALDYITEQQVCINLGDAFKDHTVFFITHRLSSVRSADVIVMMDQGSVVEQGSHDELMA 992
Query: 563 KGGIFSEMMKAGGVYG 578
G + + + G G
Sbjct: 993 LKGRYYYLYQQQGAGG 1008
>gb|AAF81747.1| (AF269224) his-tagged-multidrug resistance glycoprotein MDR1
[synthetic construct]
Length = 1287
Score = 259 bits (655), Expect = 6e-68
Identities = 171/554 (30%), Positives = 294/554 (52%), Gaps = 27/554 (4%)
Query: 28 LIILMSYTNSIVPVLIRNAIDKGVSTGAYKVA-IRYGLLILLVGVLNGVFSLAGRYLLVK 86
+II S TN+ + N +++ ++T AY + I G+L+ ++ AGR +L
Sbjct: 98 VIINESITNNTQHFI--NHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQILK- 154
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
+R F AI R E+ +FD G+L +R+T+D +I + ++ M SI
Sbjct: 155 --------IRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSIA 206
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 207 TFFTGFIVGFTRGWKLTLV-ILAISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEV 265
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + A FL++ + + F+YG
Sbjct: 266 LAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYG 325
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP---- 321
++ + ++G+++ +L + + +I + AA +F +ID+ P
Sbjct: 326 TSLVLSSEYSIGQVLTVFFSVLIGAFSIGQASPSIEAFANARGAAYEIFKIIDNKPSIDS 385
Query: 322 --KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
KS PD N +G +EF++V +Y + + V LKG++ KV+ G+ V + G G G
Sbjct: 386 YSKSGHKPD-----NIKGNLEFKNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCG 440
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAK 437
KS+ ++L+ R Y PT G V IDG ++ I +LR+I V QEP +F +I ENI +
Sbjct: 441 KSTTVQLMQRLYDPTDGMVCIDGQDIRTINVRHLREITGVVSQEPVLFATTIAENIRYGR 500
Query: 438 PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+
Sbjct: 501 ENVTMDEIEKAVKEANAYDFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARALVRNPKIL 560
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
LLD+ S LD E+E + L + + +T ++++ RLS V+ D + DG IVE G
Sbjct: 561 LLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNH 620
Query: 558 EELIKKGGIFSEMM 571
+EL+K+ GI+ +++
Sbjct: 621 DELMKEKGIYFKLV 634
Score = 238 bits (601), Expect = 1e-61
Identities = 158/568 (27%), Positives = 297/568 (51%), Gaps = 23/568 (4%)
Query: 21 HFLIGLFLIILMSYTNSIVPVLIRNAI-----DKGVSTGAYKVAIRYGLLILLVGVLNGV 75
+F++G+F I+ ++ I D+ T + + +L L++G+++ +
Sbjct: 718 YFVVGIFCAIINGGLQPAFSIIFSRIIGIFTRDEDPETKRQNSNM-FSVLFLVLGIISFI 776
Query: 76 FSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITRF 133
+ KA + LR FR++ R ++ +FD K +G L +R+ ND ++
Sbjct: 777 TFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGA 836
Query: 134 LSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
+ R+ ++ +I IIISL Y +TL ++A++ I + G+ + + + D
Sbjct: 837 IGSRLAVITQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKD 894
Query: 190 KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNA 249
K + IAT I +T+ SL+ E+ + ++Q + Y +++ I + +
Sbjct: 895 KKELEGA--GKIATEAIENFRTVVSLTREQKFEYMYAQSLQVPYRNSLRKAHIFGVSFSI 952
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
++ + + F +G + + +++ + ++ + + D ++ +
Sbjct: 953 TQAMMYFSYAGCFRFGAYLVANEFMNFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVS 1012
Query: 310 ASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPG 365
A+ + +I+ +P ID P ++ + G + F +V Y T VL+G+S +VK G
Sbjct: 1013 AAHVIMIIEKSPL-IDSYSPHGLKPNTLEGNVTFNEVVFNYPTRPDIPVLQGLSLEVKKG 1071
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
+ + + G G GKS++++L+ RFY P G VLIDG + + + LR + V QEP +F
Sbjct: 1072 QTLALVGSSGCGKSTVVQLLERFYDPLAGSVLIDGKEIKHLNVQWLRAHLGIVSQEPILF 1131
Query: 426 NRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+ SI ENIA + + EE+ +AAK A IH FI +LP+ Y+T VG+KG LSGGQ+QR
Sbjct: 1132 DCSIAENIAYGDNSRVVSHEEIMQAAKEANIHHFIETLPEKYNTRVGDKGTQLSGGQKQR 1191
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
IA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++++ RLS ++ D +
Sbjct: 1192 IAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLI 1251
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEMM 571
+V ++GK+ E G ++L+ + GI+ M+
Sbjct: 1252 VVFQNGKVKEHGTHQQLLAQKGIYFSMI 1279
>gb|AAA59575.1| (M14758) P-glycoprotein [Homo sapiens]
Length = 1280
Score = 259 bits (654), Expect = 8e-68
Identities = 156/494 (31%), Positives = 268/494 (53%), Gaps = 15/494 (3%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI R E+ +FD G+L +R+T+D +I + ++ M S+
Sbjct: 139 AAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEVIGDKIGMFFQSMA 198
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 199 TFFTGFIVGFTRGWKLTLV-ILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEV 257
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + A FL++ + + F+YG
Sbjct: 258 LAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYG 317
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP---- 321
++ ++G+++ +L + + +I + AA +F +ID+ P
Sbjct: 318 TTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDS 377
Query: 322 --KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
KS PD N +G +EFR+V +Y + + V LKG++ KV+ G+ V + G G G
Sbjct: 378 YSKSGHKPD-----NIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCG 432
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAK 437
KS+ ++L+ R Y PT+G V +DG ++ I LR+I+ V QEP +F +I ENI +
Sbjct: 433 KSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGR 492
Query: 438 PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+
Sbjct: 493 ENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKIL 552
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
LLD+ S LD E+E + L + + +T ++++ RLS V+ D + DG IVE G
Sbjct: 553 LLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNH 612
Query: 558 EELIKKGGIFSEMM 571
+EL+K+ GI+ +++
Sbjct: 613 DELMKEKGIYFKLV 626
Score = 237 bits (598), Expect = 3e-61
Identities = 151/522 (28%), Positives = 279/522 (52%), Gaps = 17/522 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L +G+++ + + KA + LR FR++ R ++ +FD K +G L
Sbjct: 755 FSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGAL 814
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ ND ++ + R+ ++ +I IIIS Y +TL ++A++ I + G
Sbjct: 815 TTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIY--GWQLTLLLLAIVPIIAIAG 872
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 873 VVEMKMLSGQALKDKKELEGA--GKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRN 930
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+++ I + + ++ + + F +G + ++ +++ + ++ +
Sbjct: 931 SLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQ 990
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT 353
+ D ++ +A+ + +I+ P ID + + + G + F +V Y T
Sbjct: 991 VSSFAPDYAKAKISAAHIIMIIEKTPL-IDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPD 1049
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VL+G+S +VK G+ + + G G GKS++++L+ RFY P G+VL+DG + ++ + L
Sbjct: 1050 IPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWL 1109
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R + V QEP +F+ SI ENIA + +QEE+ RAAK A IH FI SLP Y T V
Sbjct: 1110 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKV 1169
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
G+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++
Sbjct: 1170 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1229
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS ++ D ++V ++G++ E G ++L+ + GI+ M+
Sbjct: 1230 IAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1271
>pir||JC4554 ABC-type transporter homolog - Staphylococcus aureus
>gi|881631|gb|AAB50179.1| (U29478) AbcA [Staphylococcus
aureus] >gi|1586530|prf||2204232A ABC transporter-like
protein [Staphylococcus aureus]
Length = 575
Score = 258 bits (653), Expect = 1e-67
Identities = 165/539 (30%), Positives = 288/539 (52%), Gaps = 18/539 (3%)
Query: 31 LMSYTNSIVPVLIRNAIDKGVSTGAYKVA-IRYGLLILLVG--VLNGVFSLAGRYLLVKA 87
L S + +VP+ +DK + V+ I + L+ L G V+N + S G YLL K
Sbjct: 30 LGSLSGLLVPLFTGRIVDK------FSVSHINWNLIALFGGIFVINALLSGLGLYLLSKI 83
Query: 88 AQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFL 147
+ +Y +R + I + +M FFDK SGQL+SR+T+DT+ I F+S ++ LL SI
Sbjct: 84 GEKIIYRIRSVLWEHIIQLKMPFFDKNESGQLMSRLTDDTKVINEFISQKLPNLLPSIVT 143
Query: 148 IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIA 207
++ SL + ++ +T++ ITI I V + ++ I + + + + +
Sbjct: 144 LVGSLIMLFILDWKMTLLTFITIPIFVLIMIPLGRIMQKISTSTQSEIANFSGLLGRVLT 203
Query: 208 GIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGK 267
++ +K + E + E+Y L +K KI A+ +V+ L ++ + +G
Sbjct: 204 EMRLVKISNTERLELDNAHKNLNEIYKLGLKQAKIAAVVQPISGIVMLLTIAIILGFGAL 263
Query: 268 AIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPP 327
I +T G L+A + Y++ + PL L + D ++++ A+SR+++++ + I+P
Sbjct: 264 EIATGAITAGTLIAMIFYVIQLSMPLINLSTLVTDYKKAVGASSRIYEIMQ---EPIEPT 320
Query: 328 DAVEISN----PRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILK 383
+A+E S G + F V Y + +L VSF++ G+ GP GSGKS+I
Sbjct: 321 EALEDSENVLIDDGVLSFEHVDFKYDV-KKILDDVSFQIPQGQVSAFVGPSGSGKSTIFN 379
Query: 384 LIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-KPNATQ 442
LI R Y+ G++ +V I R+ + YV Q + + +IR+NI + +
Sbjct: 380 LIERMYEIESGDIKYGLESVYDIPLSKWRRKIGYVMQSNSMMSGTIRDNILYGINRHVSD 439
Query: 443 EEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
EE+ AK+A HDFI +GYDT+VGE+G+ LSGGQRQRI +AR+ + NP I+LLD+
Sbjct: 440 EELINYAKLANCHDFIMQFDEGYDTLVGERGLKLSGGQRQRIDIARSFVKNPDILLLDEA 499
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI 561
+NLD+E+E K+ E L+ +++ +T +++ RLS +K ++ + G++ G EL+
Sbjct: 500 TANLDSESELKIQEALETLMEGRTTIVIRDRLSTLKKPVKLCGLDKGQVTGKGTHSELM 558
>gi|7305539 ATP-binding cassette, sub-family B, member 2; ATP dependent
transport protein family member; antigen
processing-associated transporter; antigen peptide
transporter; peptide supply factor 1; histocompatibility
antigen modifier 1 [Mus musculus]
>gi|2506116|sp|P21958|TAP1_MOUSE ANTIGEN PEPTIDE
TRANSPORTER 1 (APT1) (HISTOCOMPATIBILITY ANTIGEN
MODIFIER 1) >gi|1399901|gb|AAB41962.1| (U60018) TAP1-d
[Mus musculus]
Length = 724
Score = 258 bits (653), Expect = 1e-67
Identities = 172/579 (29%), Positives = 295/579 (50%), Gaps = 10/579 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
R + + L R+L +L + L L+IL +P D + R
Sbjct: 143 RDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAIPFFTGRITDWILQDKTVPSFTR 202
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
L+ ++ + + A + + + + FRA+ R E FF K +G + S
Sbjct: 203 NIWLMSILTIASTALEFASDGIYNITMGHMHGRVHREVFRAVLRQETGFFLKNPAGSITS 262
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+T DT + +S + +LL+ + + L +M + LT+V LI + ++ L
Sbjct: 263 RVTEDTANVCESISDTLSLLLWYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLG 322
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK-AM 240
+ + K++ +A ++ + T++S + EE KF Q+ EE+ +LN K A+
Sbjct: 323 KVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEAL 382
Query: 241 KITALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
A V G+ + + Y GG+ +I+ T++ G LV+F+ Y L ++ L
Sbjct: 383 AYVAEVWTTS--VSGMLLKVGILYLGGQLVIRGTVSSGNLVSFVLYQLQFTQAVQVLLSL 440
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKG 357
+Q+++ ++ ++F+ +D P S ++ SN +G +EF+DV Y V L+G
Sbjct: 441 YPSMQKAVGSSEKIFEYLDRTPCS-PLSGSLAPSNMKGLVEFQDVSFAYPNQPKVQVLQG 499
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
++F + PG + GP GSGKS++ L+ Y+PT G++L+DG + + L VA
Sbjct: 500 LTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQRLVQYDHHYLHTQVAA 559
Query: 418 VPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
V QEP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G L
Sbjct: 560 VGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDFISGFPQGYDTEVGETGNQL 619
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRL 534
SGGQRQ +ALARA++ P +++LDD S LDA + ++ L E + +T L+++Q+L
Sbjct: 620 SGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQL 679
Query: 535 SLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
SL + ++ +++G + E G +L+K+GG + M++A
Sbjct: 680 SLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEA 718
>dbj|BAA87071.1| (AB029153) multi-drug resistance related mRNA [Felis catus]
Length = 1163
Score = 258 bits (653), Expect = 1e-67
Identities = 156/490 (31%), Positives = 269/490 (54%), Gaps = 7/490 (1%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA + +R F AI R E+ +FD G+L +R+T+D +I + ++ M S+
Sbjct: 80 AAGRQILKIRKQFFHAIMRQEVGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMA 139
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
I LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 140 TFFIGFIVGFTRGWKLTLV-ILAISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEV 198
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + FL++ + + F+YG
Sbjct: 199 LAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGIAFLLIYASYALAFWYG 258
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
++ + ++G+++ +L + + +I + AA +F +ID+ P SID
Sbjct: 259 TSLVLSHEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKP-SID 317
Query: 326 P--PDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSI 381
+ + N +G +EF++V +Y + + V LKG++ KV+ G+ V + G G GKS+
Sbjct: 318 SYSKNGHKPDNIKGNLEFKNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTT 377
Query: 382 LKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT 441
++L+ R Y PT G V IDG ++ I LR+I+ V QEP +F +I ENI + N T
Sbjct: 378 VQLMQRLYDPTDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVT 437
Query: 442 QEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDD 501
EE+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+LLD+
Sbjct: 438 MEEIEKAVKEANAYDFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDE 497
Query: 502 PVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI 561
S LD+E+E + L + + +T ++V+ RLS ++ D + DG IVE G +EL+
Sbjct: 498 ATSALDSESEAVVQVALDKARKGRTTIVVAHRLSTIRNADVIAGFDDGVIVEKGNHDELM 557
Query: 562 KKGGIFSEMM 571
K+ GI+ +++
Sbjct: 558 KEEGIYFKLV 567
Score = 208 bits (524), Expect = 1e-52
Identities = 147/516 (28%), Positives = 263/516 (50%), Gaps = 25/516 (4%)
Query: 21 HFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR------YGLLILLVGVLNG 74
+F++G+F I+ V++ I GV T + + LL L++G+++
Sbjct: 651 YFVVGIFCAIINGGLQPAFSVILSRII--GVFTRVEDPETKRQNSNIFSLLFLVLGIISS 708
Query: 75 VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITR 132
+ + KA + LR FR++ R ++ +FD K +G L +R+ ND ++
Sbjct: 709 ITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKG 768
Query: 133 FLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
+ R+ ++ +I IIISL Y +TL ++A++ I + G+ + + +
Sbjct: 769 AIGSRLAIITQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAGVVEMKMLSGQALK 826
Query: 189 DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGN 248
DK + +AT I +T+ SL+ E+ + ++Q + Y +++ I + +
Sbjct: 827 DKKELEGA--GKVATEAIENFRTVVSLTREQKFEYMYAQSLQVPYRNSLRKAHIFGISFS 884
Query: 249 APFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLA 308
++ + + F +G + + +++ + ++ + + D ++
Sbjct: 885 ITQAMMYFSYAGCFRFGAYLVAHEFMDFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKV 944
Query: 309 AASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKP 364
+A+ + +I+ P ID + + + G + F +V Y T VL+G+S +VK
Sbjct: 945 SAAHVIMIIEKIPL-IDSYSTEGLMPNTLEGNVTFNEVMFNYPTRPDIPVLQGLSLEVKK 1003
Query: 365 GEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI 424
G+ + + G G GKS++++L+ RFY P G VLIDG + + + LR + V QEP +
Sbjct: 1004 GQTLALVGSSGCGKSTVVQLLERFYDPMAGTVLIDGKEIKHLNVQWLRAHMGIVSQEPIL 1063
Query: 425 FNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQ 482
F+ SI ENIA + +QEE+ RAAK A IH FI +LP Y+T VG+KG LSGGQ+Q
Sbjct: 1064 FDCSIGENIAYGDNSRVVSQEEIVRAAKEANIHPFIETLPDKYNTRVGDKGTQLSGGQKQ 1123
Query: 483 RIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDL 518
RIA+ARA++ P+I+LLD+ S LD E+EK + E L
Sbjct: 1124 RIAIARALVRQPRILLLDEATSALDTESEKVVQEAL 1159
>pir||D82146 transport ATP-binding protein MsbA VC1878 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9656409|gb|AAF95026.1| (AE004263) transport
ATP-binding protein MsbA [Vibrio cholerae]
Length = 582
Score = 258 bits (653), Expect = 1e-67
Identities = 164/564 (29%), Positives = 289/564 (51%), Gaps = 6/564 (1%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
RL +Y+R + ++ +++ + ++ + L++ +D+G +IL +
Sbjct: 15 RLWTYIRLYKAGLVVSTIALVINAAADTYMISLLKPLLDEGFGNAESNFLRILPFMILGL 74
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTER 129
+ G+ A Y L + V +R F + FFD+ +G L+SRIT D+E+
Sbjct: 75 MFVRGLSGFASSYCLSWVSGNVVMQMRRRLFNHFMHMPVRFFDQESTGGLLSRITYDSEQ 134
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK-VRPIY 188
+ S R + + II L ++ N + LI +A VV ++ K R I
Sbjct: 135 VAGATS-RALVSIVREGASIIGLLTLMFWNSWQLSLVLIVVAPVVAFAISFVSKRFRKIS 193
Query: 189 DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGN 248
++ G + S A + G K + S +E + +F + + + +K + ++
Sbjct: 194 RNMQTAMGHVTSSAEQMLKGHKVVLSYGGQEVERKRFDKVSNSMRQQTMKLVSAQSIADP 253
Query: 249 APFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLA 308
++ LA+ + + I+ LT G + M +M PL+AL + QR +A
Sbjct: 254 VIQMIASLALFAVLFLASVDSIRAELTPGTFTVVFSAMFGLMRPLKALTSVTSEFQRGMA 313
Query: 309 AASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH-TGRTVLKGVSFKVKPGEK 367
A LF ++D + + E N GE++ +DV TY + L VSF + G+
Sbjct: 314 ACQTLFGLMDLETERDNGKYEAERVN--GEVDVKDVTFTYQGKEKPALSHVSFSIPQGKT 371
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
V + G GSGKS+I L RFY G + +DG +V K NLR+ A V Q +FN
Sbjct: 372 VALVGRSGSGKSTIANLFTRFYDVDSGSICLDGHDVRDYKLTNLRRHFALVSQNVHLFND 431
Query: 428 SIRENIALAKPNA-TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIAL 486
+I NIA A T+E++E+AA+ A +FI ++P+G DTV+GE G +LSGGQRQR+A+
Sbjct: 432 TIANNIAYAAEGEYTREQIEQAARQAHAMEFIENMPQGLDTVIGENGTSLSGGQRQRVAI 491
Query: 487 ARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVM 546
ARA+L + +++LD+ S LD E+E+ + L E+ ++KT L+++ RLS ++ D ++V+
Sbjct: 492 ARALLRDAPVLILDEATSALDTESERAIQAALDELQKNKTVLVIAHRLSTIEQADEILVV 551
Query: 547 KDGKIVEDGKPEELIKKGGIFSEM 570
+G+I+E G+ +L+ + G ++++
Sbjct: 552 DEGEIIERGRHADLLAQDGAYAQL 575
>sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1)
>gi|1070659|pir||DVHU1 multidrug resistance protein 1 -
human >gi|386862|gb|AAA59576.1| (M29447) P glycoprotein
[Homo sapiens]
Length = 1280
Score = 258 bits (652), Expect = 1e-67
Identities = 156/494 (31%), Positives = 268/494 (53%), Gaps = 15/494 (3%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI R E+ +FD G+L +R+T+D +I + ++ M S+
Sbjct: 139 AAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMA 198
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 199 TFFTGFIVGFTRGWKLTLV-ILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEV 257
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + A FL++ + + F+YG
Sbjct: 258 LAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYG 317
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP---- 321
++ ++G+++ +L + + +I + AA +F +ID+ P
Sbjct: 318 TTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDS 377
Query: 322 --KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
KS PD N +G +EFR+V +Y + + V LKG++ KV+ G+ V + G G G
Sbjct: 378 YSKSGHKPD-----NIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCG 432
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAK 437
KS+ ++L+ R Y PT+G V +DG ++ I LR+I+ V QEP +F +I ENI +
Sbjct: 433 KSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGR 492
Query: 438 PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+
Sbjct: 493 ENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKIL 552
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
LLD+ S LD E+E + L + + +T ++++ RLS V+ D + DG IVE G
Sbjct: 553 LLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNH 612
Query: 558 EELIKKGGIFSEMM 571
+EL+K+ GI+ +++
Sbjct: 613 DELMKEKGIYFKLV 626
Score = 237 bits (598), Expect = 3e-61
Identities = 151/522 (28%), Positives = 279/522 (52%), Gaps = 17/522 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L +G+++ + + KA + LR FR++ R ++ +FD K +G L
Sbjct: 755 FSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGAL 814
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ ND ++ + R+ ++ +I IIIS Y +TL ++A++ I + G
Sbjct: 815 TTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIY--GWQLTLLLLAIVPIIAIAG 872
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 873 VVEMKMLSGQALKDKKELEGA--GKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRN 930
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+++ I + + ++ + + F +G + ++ +++ + ++ +
Sbjct: 931 SLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQ 990
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT 353
+ D ++ +A+ + +I+ P ID + + + G + F +V Y T
Sbjct: 991 VSSFAPDYAKAKISAAHIIMIIEKTPL-IDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPD 1049
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VL+G+S +VK G+ + + G G GKS++++L+ RFY P G+VL+DG + ++ + L
Sbjct: 1050 IPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWL 1109
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R + V QEP +F+ SI ENIA + +QEE+ RAAK A IH FI SLP Y T V
Sbjct: 1110 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKV 1169
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
G+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++
Sbjct: 1170 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1229
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS ++ D ++V ++G++ E G ++L+ + GI+ M+
Sbjct: 1230 IAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1271
>sp|P75094|Y015_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG015 HOMOLOG
(D12_ORF634) >gi|2146673|pir||S73461 transport
ATP-binding protein msbA - Mycoplasma pneumoniae
(strain ATCC 29342) >gi|1673794|gb|AAB95783.1|
(AE000015) transport ATP-binding protein [Mycoplasma
pneumoniae]
Length = 634
Score = 258 bits (652), Expect = 1e-67
Identities = 144/522 (27%), Positives = 276/522 (52%), Gaps = 22/522 (4%)
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+++ +L F++A YL +K Q LR A+ IQ FFD +G L+SR+TN
Sbjct: 118 VVVAYILIFSFNVAQNYLGLKLYQEICALLRWKAYLKIQSMSTSFFDTQNNGDLMSRLTN 177
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
D I + + S+F+++ + + ++ + +++L + ++ L+ + K R
Sbjct: 178 DVYNINNLYAQVGGQTIQSLFILMTTATILFVLSPVIALISLTVLIALIALSFLFLKKAR 237
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
Y K+++ G ++ ++ K + L ++E + F + N + + +KA
Sbjct: 238 AAYAKVQNNLGDMSGYIEEVLSNHKVVHVLKLQEVMIDNFDKYNRPMVNPTIKANTY--- 294
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAF------LTYMLTMMWPLRALGFT 299
A F+ + Y I +V + +F ++ML+ + LR
Sbjct: 295 ---AVFIYSWFGFISNITYLASISIATAFSVNNIPSFGVSAINYSFMLSYIAALRQTALP 351
Query: 300 IGDI-------QRSLAAASRLFDVID-SAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG 351
+ I Q + + R+F ++D +P+ ++ N +G I F V Y
Sbjct: 352 LNQIFSLWNLIQLGIVSGERVFKILDLESPQK--QATITKLPNIKGNIRFEKVVFGYSAD 409
Query: 352 RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
+ +L G+ F VK G+ V I GP G+GKS+I+ L+ +FYKP G++ +D ++++
Sbjct: 410 KPILTGIDFSVKHGDIVAIVGPTGAGKSTIINLLMKFYKPFAGKIYMDNFEISEVSETAW 469
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGE 471
R+ ++ V Q+PF+F+ +I+ENI + + +AT EE+ A K+A HDFI LP+GY+T +
Sbjct: 470 REKISIVLQDPFLFSGTIKENIRMGRQDATDEEIIEACKVANAHDFIMRLPQGYNTFISN 529
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
K LS G+RQ + +ARA++ N ++LLD+ S++D +EK + + + +++DKT+ I+S
Sbjct: 530 KTDYLSVGERQLLTIARAVIRNAPVLLLDEATSSIDVHSEKLIQQSIGRLMKDKTSFIIS 589
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
RLS+++ +IV+ DGK++E G E+L+++ G ++ + ++
Sbjct: 590 HRLSIIRNATLIIVINDGKVLEMGNHEQLMRQNGFYARLKRS 631
>sp|P57551|MDLA_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLA
>gi|10039142|dbj|BAB13176.1| (AP001119) multidrug
resistance-like ATP-binding protein mdl [Buchnera sp.
APS]
Length = 589
Score = 258 bits (652), Expect = 1e-67
Identities = 167/556 (30%), Positives = 300/556 (53%), Gaps = 12/556 (2%)
Query: 22 FLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR-YGLLILLVGVLNGVFSLAG 80
+L + L+I+++ + P ++ ID + + V I + L+I LV V+ +
Sbjct: 18 YLGAILLLIIIATLQLLPPKIVGVLIDLIIKKNMHGVQILPWILIIFLVAVIVYILRYLW 77
Query: 81 RYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRM 140
R LL A+ LR+ + + + FF K +G LI+R TND +R+ V
Sbjct: 78 RILLFGASYQLATELRVKFYTYLSQQSQIFFLKNRTGDLIARATNDVDRVVFAAGEGVLT 137
Query: 141 LLYSIFLIIISLYYM-VRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIA 199
L+ S+ + L M +++ LT+++LI + I+ L Y ++ + + ++
Sbjct: 138 LVDSLVMGFSVLIVMSTQISFLLTIISLIPMPIMAILIKKYGKELHETFRHAQISFSLLN 197
Query: 200 SIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMS 259
+ + I+ I++ +E+N KF+ N++ KI A + P + L +A S
Sbjct: 198 NQTQEILTSIRMIRAFGLEKNQSNKFNIITRNTGKKNMEVAKIDARFD--PVIYLSVAFS 255
Query: 260 TMFYY--GGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVI 317
+ GG + N +++G+L +F+ Y+ M+WP+ AL + ++R AA R+ +I
Sbjct: 256 NLLAIIGGGWLVWNNQISIGQLTSFIMYLGLMIWPMLALAWMFNIVERGSAAWDRIHSII 315
Query: 318 DSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPPG 375
+ K + D P I ++ Y+ + LK + +KPG + I GP G
Sbjct: 316 N---KKLYIEDGKNNIPPYPGILNINIKKFYYPNNQKPSLKDIRILIKPGNTLGICGPTG 372
Query: 376 SGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIAL 435
SGKS++L LI R + K E+ +++ +IK ++ R+ +A V Q F+F+ +I NI+L
Sbjct: 373 SGKSTLLMLIQRQFNFKKEEIHYHSLSLLEIKIDDWRRRIAVVNQTSFLFSDTISNNISL 432
Query: 436 AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPK 495
KPNA+Q+E+E AK+A +H I LP+ Y+T VGE+G+ LSGGQ+QR+ +ARA+L+N +
Sbjct: 433 GKPNASQKEIEEVAKLADVHKDIIDLPERYETQVGERGVMLSGGQKQRVCIARALLLNAE 492
Query: 496 IVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIV-SQRLSLVKLVDRVIVMKDGKIVED 554
I++LDD +S +DA+TE +++++ E + K +LI+ + RLS + D +IV+K G I++
Sbjct: 493 ILILDDALSAVDAQTENNILKNINEWKKKKHSLIITTHRLSALINSDEIIVIKSGSIIQR 552
Query: 555 GKPEELIKKGGIFSEM 570
G +LI++ + M
Sbjct: 553 GNHLKLIQEKNWYKSM 568
>pir||A37779 histocompatibility antigen modifier 1 - mouse
>gi|199305|gb|AAA39570.1| (M55637) HAM1 [Mus musculus]
Length = 577
Score = 257 bits (651), Expect = 2e-67
Identities = 158/483 (32%), Positives = 265/483 (54%), Gaps = 10/483 (2%)
Query: 98 DAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVR 157
+ FRA+ R E FF K +G + SR+T DT + +S + +LL+ + + L +M
Sbjct: 92 EVFRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISDTLSLLLWYLGRALCLLVFMFW 151
Query: 158 MNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSV 217
+ LT+V LI + ++ L + + K++ +A ++ + T++S +
Sbjct: 152 GSPYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFAN 211
Query: 218 EENVQTKFSQENEELYSLNVK-AMKITALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLT 275
EE KF Q+ EE+ +LN K A+ A V G+ + + Y GG+ +I+ T++
Sbjct: 212 EEGEAQKFRQKLEEMKTLNKKEALAYVAEVWTTS--VSGMLLKVGILYLGGQLVIRGTVS 269
Query: 276 VGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP 335
G LV+F+ Y L ++ L +Q+++ ++ ++F+ +D P S ++ SN
Sbjct: 270 SGNLVSFVLYQLQFTQAVQVLLSLYPSMQKAVGSSEKIFEYLDRTPCS-PLSGSLAPSNM 328
Query: 336 RGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTK 393
+G +EF+DV Y V L+G++F + PG + GP GSGKS++ L+ Y+PT
Sbjct: 329 KGLVEFQDVSFAYPNQPKVQVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTG 388
Query: 394 GEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIA 452
G++L+DG + + L VA V QEP +F RS RENIA T EE+ A +
Sbjct: 389 GQLLLDGQRLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVES 448
Query: 453 KIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEK 512
HDFI+ P+GYDT VGE G LSGGQRQ +ALARA++ P +++LDD S LDA +
Sbjct: 449 GAHDFISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPLLLILDDATSALDAGNQL 508
Query: 513 KLVEDLKEILQ--DKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++ L E + +T L+++Q+LSL + ++ +++G + E G +L+K+GG + M
Sbjct: 509 RVQRLLYESPKRASRTVLLITQQLSLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAM 568
Query: 571 MKA 573
++A
Sbjct: 569 VEA 571
>gb|AAB41964.1| (U60020) TAP1-g7 [Mus musculus] >gi|1399911|gb|AAB41967.1| (U60023)
TAP1-cas [Mus musculus castaneus]
Length = 724
Score = 257 bits (651), Expect = 2e-67
Identities = 158/483 (32%), Positives = 265/483 (54%), Gaps = 10/483 (2%)
Query: 98 DAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVR 157
+ FRA+ R E FF K +G + SR+T DT + +S + +LL+ + + L +M
Sbjct: 239 EVFRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISDTLSLLLWYLGRALCLLVFMFW 298
Query: 158 MNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSV 217
+ LT+V LI + ++ L + + K++ +A ++ + T++S +
Sbjct: 299 GSPYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFAN 358
Query: 218 EENVQTKFSQENEELYSLNVK-AMKITALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLT 275
EE KF Q+ EE+ +LN K A+ A V G+ + + Y GG+ +I+ T++
Sbjct: 359 EEGEAQKFRQKLEEMKTLNKKEALAYVAEVWTTS--VSGMLLKVGILYLGGQLVIRGTVS 416
Query: 276 VGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP 335
G LV+F+ Y L ++ L +Q+++ ++ ++F+ +D P S ++ SN
Sbjct: 417 SGNLVSFVLYQLQFTQAVQVLLSLYPSMQKAVGSSEKIFEYLDRTPCS-PLSGSLAPSNM 475
Query: 336 RGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTK 393
+G +EF+DV Y V L+G++F + PG + GP GSGKS++ L+ Y+PT
Sbjct: 476 KGLVEFQDVSFAYPNQPKVQVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTG 535
Query: 394 GEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIA 452
G++L+DG + + L VA V QEP +F RS RENIA T EE+ A +
Sbjct: 536 GQLLLDGQRLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVES 595
Query: 453 KIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEK 512
HDFI+ P+GYDT VGE G LSGGQRQ +ALARA++ P +++LDD S LDA +
Sbjct: 596 GAHDFISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPLLLILDDATSALDAGNQL 655
Query: 513 KLVEDLKEILQ--DKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++ L E + +T L+++Q+LSL + ++ +++G + E G +L+K+GG + M
Sbjct: 656 RVQRLLYESPKRASRTVLLITQQLSLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAM 715
Query: 571 MKA 573
++A
Sbjct: 716 VEA 718
>gi|6679297 P glycoprotein 2 [Mus musculus] >gi|126929|sp|P21440|MDR2_MOUSE
MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2)
>gi|72476|pir||DVMS2 multidrug resistance protein 2 -
mouse >gi|387428|gb|AAA39516.1| (J03398) multidrug
resistance protein [Mus musculus]
Length = 1276
Score = 257 bits (650), Expect = 2e-67
Identities = 179/603 (29%), Positives = 304/603 (49%), Gaps = 41/603 (6%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNS----IVPVLIRNAIDKGV-STGAY 56
+K +N LI LL+ R + +FL LM+ + ++ ++ DK V +TG +
Sbjct: 31 KKKVN-LIGLLTLFRYSDWQDKLFMFLGTLMAIAHGSGLPLMMIVFGEMTDKFVDNTGNF 89
Query: 57 KVAIRYGLLILLVGVLN--------------GVFSLAGRYLLVK----AAQYAVYYLRMD 98
+ + + L +L G + G L Y+ V AA + +R
Sbjct: 90 SLPVNFSLSMLNPGRILEEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQK 149
Query: 99 AFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRM 158
F AI R EM +FD + +L +R+T+D +I+ + +V M +I
Sbjct: 150 FFHAILRQEMGWFDIKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIR 209
Query: 159 NITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGTIAGIKTIKSLSV 217
LT+V ++ I+ ++GL+T K+ + DK ++A I+T+ +
Sbjct: 210 GWKLTLV-IMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEAPGAIRTVIAFGG 268
Query: 218 EENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVG 277
+ ++ + E + +K + FL++ + + F+YG +I T+G
Sbjct: 269 QNKELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIG 328
Query: 278 ELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP-------PDAV 330
+ +L + + I + AA +FD+ID+ PK ID PD
Sbjct: 329 NAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPK-IDSFSERGHKPD-- 385
Query: 331 EISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARF 388
N +G +EF DV +Y + + LKG++ KVK G+ V + G G GKS+ ++L+ R
Sbjct: 386 ---NIKGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRL 442
Query: 389 YKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA 448
Y PT+G++ IDG ++ LR+I+ V QEP +F+ +I ENI + N T +E+E+A
Sbjct: 443 YDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMDEIEKA 502
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
K A +DFI LP+ +DT+VG++G LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD
Sbjct: 503 VKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDT 562
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFS 568
E+E ++ L + + +T ++++ RLS ++ D + +DG IVE G EL+KK GI+
Sbjct: 563 ESEAEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKKEGIYF 622
Query: 569 EMM 571
++
Sbjct: 623 RLV 625
Score = 228 bits (575), Expect = 1e-58
Identities = 155/527 (29%), Positives = 271/527 (51%), Gaps = 27/527 (5%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ L+ L +GVL+ + KA + LR AF+A+ R +M +FD K +G L
Sbjct: 751 FSLVFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGAL 810
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ D ++ ++ ++ + IIIS Y +TL +++++ V G
Sbjct: 811 STRLATDAAQVQGATGTKLALIAQNTANLGTGIIISFIY--GWQLTLLLLSVVPFIAVAG 868
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + DK + IAT I I+T+ SL+ E ++ + ++ Y
Sbjct: 869 IVEMKMLAGNAKRDKKEMEAA--GKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRN 926
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+V+ I + + + + + F +G I+ + +++ + ++ L
Sbjct: 927 SVRKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGH 986
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP-------PDAVEISNPRGEIEFRDVWLTY 348
D ++ +A+ LF + + P ID PD E G + F +V Y
Sbjct: 987 ASSFAPDYAKAKLSAAYLFSLFERQPL-IDSYSGEGLWPDKFE-----GSVTFNEVVFNY 1040
Query: 349 HTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
T V L+G+S +VK G+ + + G G GKS++++L+ RFY P G VL+DG K+
Sbjct: 1041 PTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVLLDGQEAKKL 1100
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT--QEEVERAAKIAKIHDFIASLPKG 464
+ LR + V QEP +F+ SI ENIA + +E+ RAAK A IH FI +LP+
Sbjct: 1101 NVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVPHDEIVRAAKEANIHPFIETLPQK 1160
Query: 465 YDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQD 524
Y+T VG+KG LSGGQ+QRIA+ARA++ P+++LLD+ S LD E+EK + E L + +
Sbjct: 1161 YNTRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREG 1220
Query: 525 KTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
+T ++++ RLS ++ D ++V+++GK+ E G ++L+ + GI+ M+
Sbjct: 1221 RTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMV 1267
>pir||T02187 hypothetical protein F14M4.17 - Arabidopsis thaliana
>gi|3522943|gb|AAC34225.1| (AC004411) putative ABC
transporter [Arabidopsis thaliana]
Length = 1286
Score = 257 bits (650), Expect = 2e-67
Identities = 165/522 (31%), Positives = 280/522 (53%), Gaps = 11/522 (2%)
Query: 57 KVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD-KTF 115
KVA+++ + L +G F +++ Q A +R + I R ++ FFD T
Sbjct: 104 KVALKF--VWLGIGTFAAAFLQLSGWMISGERQAA--RIRSLYLKTILRQDIAFFDIDTN 159
Query: 116 SGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVG 175
+G+++ R++ DT I + +V + + + LT+V L +I ++V
Sbjct: 160 TGEVVGRMSGDTVLIQDAMGEKVGKAIQLLATFVGGFVIAFVRGWLLTLVMLSSIPLLVM 219
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
A+ + + + A++ TI I+T+ S + E+ + +++ Y
Sbjct: 220 AGALLAIVIAKTASRGQTAYAKAATVVEQTIGSIRTVASFTGEKQAISNYNKHLVTAYKA 279
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
V T L FLV+ + + +YGGK I+ T G+++ + +LT L
Sbjct: 280 GVIEGGSTGLGLGTLFLVVFCSYALAVWYGGKLILDKGYTGGQVLNIIIAVLTGSMSLGQ 339
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTY--HTG 351
+ AAA ++F+ I+ P +ID + + + +G+IE +DV+ TY
Sbjct: 340 TSPCLSAFAAGQAAAYKMFETIERRP-NIDSYSTNGKVLDDIKGDIELKDVYFTYPARPD 398
Query: 352 RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
+ +G S + G V + G GSGKS+++ LI RFY P G+VLIDG+N+ + + + +
Sbjct: 399 EQIFRGFSLFISSGTTVALVGQSGSGKSTVVSLIERFYDPQAGDVLIDGINLKEFQLKWI 458
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGE 471
R + V QEP +F SI++NIA K +AT EE++ AA++A F+ LP+G DT+VGE
Sbjct: 459 RSKIGLVSQEPVLFTASIKDNIAYGKEDATTEEIKAAAELANASKFVDKLPQGLDTMVGE 518
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
G LSGGQ+QRIA+ARA+L +P+I+LLD+ S LDAE+E+ + E L I+ ++T ++V+
Sbjct: 519 HGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERVVQEALDRIMVNRTTVVVA 578
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
RLS V+ D + V+ GKIVE G EL+K G +S++++
Sbjct: 579 HRLSTVRNADMIAVIHQGKIVEKGSHTELLKDPEGAYSQLIR 620
Score = 233 bits (588), Expect = 4e-60
Identities = 149/522 (28%), Positives = 277/522 (52%), Gaps = 15/522 (2%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK--TFSGQL 119
+ ++ +++G + + A + A V +R F + E+ +FD+ SG +
Sbjct: 762 WAIIFMVLGFASIIAYPAQTFFFAIAGCKLVQRIRSMCFEKVVHMEVGWFDEPENSSGTI 821
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R++ D I + + + ++ I+ L L V L + ++
Sbjct: 822 GARLSADAATIRGLVGDSLAQTVQNLSSILAGLIIAFLACWQLAFVVLAMLPLIALNGFL 881
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
Y ++ + G + +A + I+T+ S E+ V +S++ E ++
Sbjct: 882 YMKFMKGFSADAKKMYGEASQVANDAVGSIRTVASFCAEDKVMNMYSKKCEGPMKNGIRQ 941
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
++ + F VL + + FY G + ++ + T + V + + LTM + +
Sbjct: 942 GIVSGIGFGFSFFVLFSSYAASFYVGAR-LVDDGKTTFDSVFRVFFALTMAAMAISQSSS 1000
Query: 300 IG-DIQRSLAAASRLFDVIDSAPKSIDPPDAVE----ISNPRGEIEFRDVWLTYHTGRTV 354
+ D ++ AA+ +F ++D K IDP +VE + N +G+IE R V Y V
Sbjct: 1001 LSPDSSKADVAAASIFAIMDRESK-IDP--SVESGRVLDNVKGDIELRHVSFKYPARPDV 1057
Query: 355 --LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR 412
+ + ++ G+ V + G GSGKS+++ L+ RFY P GE+ +DGV + ++ + LR
Sbjct: 1058 QIFQDLCLSIRAGKTVALVGESGSGKSTVIALLQRFYDPDSGEITLDGVEIKSLRLKWLR 1117
Query: 413 KIVAYVPQEPFIFNRSIRENIALAKP-NATQEEVERAAKIAKIHDFIASLPKGYDTVVGE 471
+ V QEP +FN +IR NIA K +A++ E+ +A+++ H FI+ L +GYDT+VGE
Sbjct: 1118 QQTGLVSQEPILFNETIRANIAYGKGGDASESEIVSSAELSNAHGFISGLQQGYDTMVGE 1177
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
+GI LSGGQ+QR+A+ARA++ +PK++LLD+ S LDAE+E+ + + L ++ ++T ++V+
Sbjct: 1178 RGIQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRVMVNRTTIVVA 1237
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
RLS +K D + V+K+G IVE GK + LI K G+++ +++
Sbjct: 1238 HRLSTIKNADVIAVVKNGVIVEKGKHDTLINIKDGVYASLVQ 1279
>gi|9961244 ATP-binding cassette, sub-family B, member 10 [Homo sapiens]
>gi|8650412|gb|AAF78198.1|AF216833_1 (AF216833) M-ABC2
protein [Homo sapiens]
Length = 738
Score = 257 bits (650), Expect = 2e-67
Identities = 165/503 (32%), Positives = 270/503 (52%), Gaps = 19/503 (3%)
Query: 82 YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT----ERITRFLSFR 137
YL+ + Q V LR F +I R E+ FFDKT +G+LI+R+++DT +T LS
Sbjct: 234 YLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDG 293
Query: 138 VRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGV 197
+R + + IS+ + V N+ +++++ ++ + Y +R + +
Sbjct: 294 LRAGAQAS--VGISMMFFVSPNLATFVLSVVPPVSIIAV--IYGRYLRKLTKVTQDSLAQ 349
Query: 198 IASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLA 257
+A I ++T+++ E K++ + + + L K A + A L L
Sbjct: 350 ATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAVARAGFFGATGLSGNLI 409
Query: 258 MSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVI 317
+ ++ Y GG + +TVGEL +FL Y + + L ++ + L A RL++++
Sbjct: 410 VLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELL 469
Query: 318 DSAPKSIDPPDAVEISNPR---GEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITG 372
+ PK P + I N + G +EF++V Y V + S + G + G
Sbjct: 470 EREPKL--PFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVG 527
Query: 373 PPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIREN 432
P GSGKS++L L+ R Y P G + +DG ++ ++ LR + V QEP +F+ SI EN
Sbjct: 528 PSGSGKSTVLSLLLRLYNPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAEN 587
Query: 433 IALAKPN---ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARA 489
IA + T EE++R A++A FI + P+G++TVVGEKG+ LSGGQ+QRIA+ARA
Sbjct: 588 IAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARA 647
Query: 490 MLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDG 549
+L NPKI+LLD+ S LDAE E + E L ++ +T L+++ RLS +K + V V+ G
Sbjct: 648 LLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQG 707
Query: 550 KIVEDGKPEELIKK-GGIFSEMM 571
KI E GK EEL+ K GI+ ++M
Sbjct: 708 KITEYGKHEELLSKPNGIYRKLM 730
>gi|11419215 ATP-binding cassette, sub-family B (MDR/TAP), member 1 [Homo
sapiens]
Length = 1279
Score = 256 bits (648), Expect = 4e-67
Identities = 157/501 (31%), Positives = 270/501 (53%), Gaps = 30/501 (5%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI R E+ +FD G+L +R+T+D +I + ++ M S+
Sbjct: 139 AAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMA 198
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 199 TFFTGFIVGFTRGWKLTLV-ILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEV 257
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + A FL++ + + F+YG
Sbjct: 258 LAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYG 317
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL-------AAASRLFDVID 318
++ ++G+++ + ++ F++G S+ AA +F +ID
Sbjct: 318 TTLVLSGEYSIGQVLTVFSVLIG--------AFSVGQASPSIEAFANARGAAYEIFKIID 369
Query: 319 SAP------KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLI 370
+ P KS PD N +G +EFR+V +Y + + V LKG++ KV+ G+ V +
Sbjct: 370 NKPSIDSYSKSGHKPD-----NIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVAL 424
Query: 371 TGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIR 430
G G GKS+ ++L+ R Y PT+G V +DG ++ I LR+I+ V QEP +F +I
Sbjct: 425 VGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIA 484
Query: 431 ENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAM 490
ENI + N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA+
Sbjct: 485 ENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARAL 544
Query: 491 LMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGK 550
+ NPKI+LLD+ S LD E+E + L + + +T ++++ RLS V+ D + DG
Sbjct: 545 VRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGV 604
Query: 551 IVEDGKPEELIKKGGIFSEMM 571
IVE G +EL+K+ GI+ +++
Sbjct: 605 IVEKGNHDELMKEKGIYFKLV 625
Score = 237 bits (598), Expect = 3e-61
Identities = 151/522 (28%), Positives = 279/522 (52%), Gaps = 17/522 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L +G+++ + + KA + LR FR++ R ++ +FD K +G L
Sbjct: 754 FSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGAL 813
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ ND ++ + R+ ++ +I IIIS Y +TL ++A++ I + G
Sbjct: 814 TTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIY--GWQLTLLLLAIVPIIAIAG 871
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 872 VVEMKMLSGQALKDKKELEGS--GKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRN 929
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+++ I + + ++ + + F +G + ++ +++ + ++ +
Sbjct: 930 SLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQ 989
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT 353
+ D ++ +A+ + +I+ P ID + + + G + F +V Y T
Sbjct: 990 VSSFAPDYAKAKISAAHIIMIIEKTPL-IDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPD 1048
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VL+G+S +VK G+ + + G G GKS++++L+ RFY P G+VL+DG + ++ + L
Sbjct: 1049 IPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWL 1108
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R + V QEP +F+ SI ENIA + +QEE+ RAAK A IH FI SLP Y T V
Sbjct: 1109 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKV 1168
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
G+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++
Sbjct: 1169 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1228
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS ++ D ++V ++G++ E G ++L+ + GI+ M+
Sbjct: 1229 IAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1270
>gi|11425328 ATP-binding cassette, sub-family B, member 10 [Homo sapiens]
Length = 738
Score = 256 bits (648), Expect = 4e-67
Identities = 165/503 (32%), Positives = 270/503 (52%), Gaps = 19/503 (3%)
Query: 82 YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT----ERITRFLSFR 137
YL+ + Q V LR F +I R E+ FFDKT +G+LI+R+++DT +T LS
Sbjct: 234 YLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDG 293
Query: 138 VRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGV 197
+R + + IS+ + V N+ +++++ ++ + Y +R + +
Sbjct: 294 LRAGAQAS--VGISMMFFVSPNLATFVLSVVPPVSIIAV--IYGRYLRKLTKVTQDSLAQ 349
Query: 198 IASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLA 257
+A I ++T+++ E K++ + + + L K A + A L L
Sbjct: 350 ATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLI 409
Query: 258 MSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVI 317
+ ++ Y GG + +TVGEL +FL Y + + L ++ + L A RL++++
Sbjct: 410 VLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELL 469
Query: 318 DSAPKSIDPPDAVEISNPR---GEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITG 372
+ PK P + I N + G +EF++V Y V + S + G + G
Sbjct: 470 EREPKL--PFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVG 527
Query: 373 PPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIREN 432
P GSGKS++L L+ R Y P G + +DG ++ ++ LR + V QEP +F+ SI EN
Sbjct: 528 PSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAEN 587
Query: 433 IALAKPN---ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARA 489
IA + T EE++R A++A FI + P+G++TVVGEKG+ LSGGQ+QRIA+ARA
Sbjct: 588 IAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARA 647
Query: 490 MLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDG 549
+L NPKI+LLD+ S LDAE E + E L ++ +T L+++ RLS +K + V V+ G
Sbjct: 648 LLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQG 707
Query: 550 KIVEDGKPEELIKK-GGIFSEMM 571
KI E GK EEL+ K GI+ ++M
Sbjct: 708 KITEYGKHEELLSKPNGIYRKLM 730
>emb|CAB76005.1| (AL157916) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 660
Score = 256 bits (648), Expect = 4e-67
Identities = 173/633 (27%), Positives = 305/633 (47%), Gaps = 60/633 (9%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
R ++ L+RL Y+R + IL S ++P++++ +D V+ G
Sbjct: 23 RSTVRALLRLWPYVRPVRARLGTAAVIAILASCVGLVIPLVLKWMVDGPVADGDPAGVWL 82
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
L +LL+G+ + R+L+ + +R D +R +QR + F D+ SGQL+S
Sbjct: 83 GALYLLLLGLAEALLFGVRRWLVARPLAGVEAGMRADLYRRLQRLPVAFHDRWASGQLLS 142
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVAL---ITIAIVVGLNT 178
R T D + FL+F + LL + I++ + M+ + TL +V L I + I G+
Sbjct: 143 RGTTDLMLLRMFLAFPLTFLLVNGVTILVGVGIMLVQDWTLGLVILGPAIPVMITCGI-- 200
Query: 179 TYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+ K + + + Q G + ++ ++ GI+ +K + F + + L ++
Sbjct: 201 -FEKKYSAVARRAQDQVGDLTTVVEESVLGIRIVKGFGRHRSQARAFHELSHTLRGTELR 259
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
++ A + +A+ G + L+ G LVAFL+ L + WP+ ++GF
Sbjct: 260 KARLLAAIWAVIVTLPEVAIGAALVVGAVQVADGALSAGTLVAFLSTALALRWPVESIGF 319
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDPPDA-----------VEISNPRGEIE------- 340
+ Q + A R F+V+D+ ++ DP +E S RG ++
Sbjct: 320 LLAMSQEAATATDRYFEVMDAEVEA-DPAAGGRAAGAMGVPPLERSRERGRVDDGGTSQA 378
Query: 341 -----------------------------FRDVWLTYHTGRT----VLKGVSFKVKPGEK 367
F V Y +L V ++PGE
Sbjct: 379 VRAPGEAPSSEQRPLPEVSANAGRPQGLRFEHVRFRYPDAAPDSTPLLTDVDLHIRPGES 438
Query: 368 VLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNR 427
+ + G GSGK+++ L+ R ++ T+G + +DG ++ + E LR +VA +EP +F+
Sbjct: 439 MALVGATGSGKTTLTALVPRLHEVTEGRITLDGEDITALSREELRSMVAVAFEEPTLFSA 498
Query: 428 SIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIAL 486
++ EN+ + A A E ++RA +A+ DF +LP+G T VGE+G++LSGGQRQR+AL
Sbjct: 499 TVGENVLMGAGEGADDEALDRALAVAQA-DFAHALPQGTGTQVGEQGLSLSGGQRQRLAL 557
Query: 487 ARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVM 546
ARA++ P+ ++LDDP+S LD TE + L+++L D TALIV+ R S V L DRV ++
Sbjct: 558 ARAVVGRPRFLVLDDPLSALDVHTEAAVEAALRQVLADTTALIVAHRPSTVLLADRVALL 617
Query: 547 KDGKIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
+G+I G EL++ ++ +M + G
Sbjct: 618 SEGRIAAVGTHHELLRTSPEYAHLMSGSDGHEG 650
>pir||S60182 ATP-binding transport protein exsA - Rhizobium meliloti
>gi|1143534|emb|CAA90568.1| (Z50189) ExsA [Sinorhizobium
meliloti] >gi|2808499|emb|CAA12529.1| (AJ225561) ExsA
protein [Sinorhizobium meliloti]
Length = 604
Score = 256 bits (648), Expect = 4e-67
Identities = 180/577 (31%), Positives = 293/577 (50%), Gaps = 45/577 (7%)
Query: 23 LIGLFLIILMS---------YTNSIVPVLIRNAIDKGVSTGAYK------VAIRYGLLIL 67
L L L +L+S Y+ +V +I A V+ A +A+ +G +IL
Sbjct: 31 LAALLLTVLLSTLADVLTPLYSGRLVDAVISGAASDDVAWNAAMAAFMMLMALSFGAIIL 90
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT--- 124
G+ SL + + AA AF IQR ++ +F+G + ++T
Sbjct: 91 RHVTFMGIVSLTLKMMSDIAAA---------AFHHIQRFSSDWHANSFAGSTVRKVTRGM 141
Query: 125 ------NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNT 178
NDT + F S + ML+ S L+ +Y M + + + ++ IA+ V L+
Sbjct: 142 WALDLLNDTLLVALFPS--IVMLVGSTALMA---WYWPMMGVIIGLGSIAFIAVTVSLSL 196
Query: 179 TYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
Y V P+ + ++ +K+ E + ++ + + +
Sbjct: 197 GY---VAPMASLANSWDTRLGGALADAVSCNTVVKAFGAEGREDARLAKVLRKWENRTRR 253
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
L G A +L + + + + + T G++ LT + LR +G
Sbjct: 254 TWSRGTLNGTAQGAMLLVLRAAVIGFALLLWARGQATAGDITFVLTSFFILQGYLREVGM 313
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSI-DPPDAVEISNPRGEIEFRDVWLTYHTGRTVL-K 356
I ++QRS+ L I + P + D P A I GEIEFRDV Y R L +
Sbjct: 314 HIRNLQRSINDMEELV-AIHAQPLGVEDRPGAKPIRITEGEIEFRDVTFHYGAHRAPLYE 372
Query: 357 GVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVA 416
G S + GE+V + G GSGK++ +KLI R + GE+ IDG N+A +LR+ +A
Sbjct: 373 GFSVNIAAGERVGLVGHSGSGKTTFIKLIQRLHDLNAGEIRIDGQNIADFTQASLRQQIA 432
Query: 417 YVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
V QEP +F+RS+ ENIA A+P ATQ ++E AA++A HDFIA+LPKGY T+VGE+G+ L
Sbjct: 433 IVQQEPILFHRSLAENIAYARPGATQRDIEEAARLASAHDFIAALPKGYGTLVGERGVKL 492
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSL 536
SGG+RQR+A+ARA L + I++LD+ S+LD+E+E + + ++ ++ +T L+V+ RLS
Sbjct: 493 SGGERQRVAIARAFLADAPILILDEATSSLDSESEVLIQQAMERLMTGRTTLVVAHRLST 552
Query: 537 VKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
V+ +DR++V G+I E+G LI+ KGGI+ + +
Sbjct: 553 VRALDRLLVFDRGRIAEEGDHGALIRVKGGIYRSLFE 589
>gi|4505769 ATP-binding cassette, sub-family B (MDR/TAP), member 1; P
glycoprotein 1/multiple drug resistance 1;
P-glycoprotein-1/multiple drug resistance-1; multidrug
resistance 1 [Homo sapiens] >gi|2353264|gb|AAB69423.1|
(AF016535) P-glycoprotein [Homo sapiens]
Length = 1279
Score = 256 bits (648), Expect = 4e-67
Identities = 157/501 (31%), Positives = 270/501 (53%), Gaps = 30/501 (5%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI R E+ +FD G+L +R+T+D +I + ++ M S+
Sbjct: 139 AAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMA 198
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 199 TFFTGFIVGFTRGWKLTLV-ILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEV 257
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + A FL++ + + F+YG
Sbjct: 258 LAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYG 317
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL-------AAASRLFDVID 318
++ ++G+++ + ++ F++G S+ AA +F +ID
Sbjct: 318 TTLVLSGEYSIGQVLTVFSVLIG--------AFSVGQASPSIEAFANARGAAYEIFKIID 369
Query: 319 SAP------KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLI 370
+ P KS PD N +G +EFR+V +Y + + V LKG++ KV+ G+ V +
Sbjct: 370 NKPSIDSYSKSGHKPD-----NIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVAL 424
Query: 371 TGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIR 430
G G GKS+ ++L+ R Y PT+G V +DG ++ I LR+I+ V QEP +F +I
Sbjct: 425 VGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIA 484
Query: 431 ENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAM 490
ENI + N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA+
Sbjct: 485 ENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARAL 544
Query: 491 LMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGK 550
+ NPKI+LLD+ S LD E+E + L + + +T ++++ RLS V+ D + DG
Sbjct: 545 VRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGV 604
Query: 551 IVEDGKPEELIKKGGIFSEMM 571
IVE G +EL+K+ GI+ +++
Sbjct: 605 IVEKGNHDELMKEKGIYFKLV 625
Score = 237 bits (598), Expect = 3e-61
Identities = 151/522 (28%), Positives = 279/522 (52%), Gaps = 17/522 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L +G+++ + + KA + LR FR++ R ++ +FD K +G L
Sbjct: 754 FSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGAL 813
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ ND ++ + R+ ++ +I IIIS Y +TL ++A++ I + G
Sbjct: 814 TTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIY--GWQLTLLLLAIVPIIAIAG 871
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 872 VVEMKMLSGQALKDKKELEGA--GKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRN 929
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+++ I + + ++ + + F +G + ++ +++ + ++ +
Sbjct: 930 SLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQ 989
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT 353
+ D ++ +A+ + +I+ P ID + + + G + F +V Y T
Sbjct: 990 VSSFAPDYAKAKISAAHIIMIIEKTPL-IDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPD 1048
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VL+G+S +VK G+ + + G G GKS++++L+ RFY P G+VL+DG + ++ + L
Sbjct: 1049 IPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWL 1108
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R + V QEP +F+ SI ENIA + +QEE+ RAAK A IH FI SLP Y T V
Sbjct: 1109 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKV 1168
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
G+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++
Sbjct: 1169 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1228
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS ++ D ++V ++G++ E G ++L+ + GI+ M+
Sbjct: 1229 IAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1270
>gb|AAD22644.1|AC007138_8 (AC007138) P-glycoprotein-like protein [Arabidopsis thaliana]
>gi|7268566|emb|CAB80675.1| (AL161493)
P-glycoprotein-like protein pgp3 [Arabidopsis thaliana]
Length = 1229
Score = 256 bits (648), Expect = 4e-67
Identities = 173/538 (32%), Positives = 284/538 (52%), Gaps = 17/538 (3%)
Query: 44 RNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAI 103
+N +K + KV +++ + L +G L F +++ Q A +R + I
Sbjct: 55 QNQSNKDIVEIVSKVCLKF--VYLGLGTLGAAFLQVACWMITGERQAA--RIRSLYLKTI 110
Query: 104 QRHEMEFFD-KTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITL 162
R ++ FFD +T +G+++ R++ DT I + +V + I + L
Sbjct: 111 LRQDIGFFDVETSTGEVVGRMSGDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGWLL 170
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
T+V L++I ++ + V + + +++ T+ I+T+ S + E+
Sbjct: 171 TLVMLVSIPLLAIAGAAMPIIVTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAM 230
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAF 282
+ + Y +VK L F V + + ++GG+ I++ T GE+V
Sbjct: 231 KSYREFINLAYRASVKQGFSMGLGLGVVFFVFFCSYALAIWFGGEMILKKGYTGGEVV-- 288
Query: 283 LTYMLTMMWPLRALGFT---IGDIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRG 337
M+T++ +LG T + AAA ++F+ I+ P SID D + + RG
Sbjct: 289 -NVMVTVVASSMSLGQTTPCLTAFAAGKAAAYKMFETIERKP-SIDAFDLNGKVLEDIRG 346
Query: 338 EIEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGE 395
EIE RDV +Y V G S + G + G GSGKSS++ LI RFY P+ G
Sbjct: 347 EIELRDVCFSYPARPMEEVFGGFSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGS 406
Query: 396 VLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIH 455
VLIDGVN+ + + + +R + V QEP +F+ SI ENI K NAT EE++ AAK+A
Sbjct: 407 VLIDGVNLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYGKENATVEEIQAAAKLANAA 466
Query: 456 DFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLV 515
+FI LP+G +T+VGE G LSGGQ+QRIA+ARA+L +P+I+LLD+ S LDAE+E+ +
Sbjct: 467 NFIDKLPRGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQ 526
Query: 516 EDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
E L ++ +T +IV+ RLS V+ D + V+ GKIVE+G EL+K G ++++++
Sbjct: 527 EALDRVMMSRTTVIVAHRLSTVRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLIR 584
Score = 245 bits (618), Expect = 1e-63
Identities = 155/522 (29%), Positives = 279/522 (52%), Gaps = 14/522 (2%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ ++ +L+GV + + YL A + +R+ F + E+ +FD + SG +
Sbjct: 704 WSMIFVLLGVASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTI 763
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
SR++ D I + + + + + + L + L ++ L+ I ++ G+N
Sbjct: 764 GSRLSADAALIKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLI-GINGY 822
Query: 180 YAMK-VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+K ++ + + + +A + I+T+ S EE V + + E+ +K
Sbjct: 823 LQIKFIKGFTADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIK 882
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELV-AFLTYMLTMMWPLRALG 297
I+ + F VL ++ FY G + + ++ FL +T + +A
Sbjct: 883 QGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTMTAIGISQASS 942
Query: 298 FTIGDIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRGEIEFRDVWLTYHTGRTV- 354
F D ++ AA+ +F +ID ID D + + N +G+IE + TY T V
Sbjct: 943 FA-PDSSKAKGAAASIFGIIDGK-SMIDSRDESGLVLENVKGDIELCHISFTYQTRPDVQ 1000
Query: 355 -LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
+ + F ++ G+ V + G GSGKS+++ L+ RFY P G + +D V + K++ + +R+
Sbjct: 1001 IFRDLCFAIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWVRQ 1060
Query: 414 IVAYVPQEPFIFNRSIRENIALAK--PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGE 471
+ V QEP +FN +IR NIA K A++ E+ AA++A H FI+S+ +GYDTVVGE
Sbjct: 1061 QMGLVGQEPVLFNDTIRSNIAYGKGGDEASEAEIIAAAELANAHGFISSIQQGYDTVVGE 1120
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
+GI LSGGQ+QR+A+ARA++ PKI+LLD+ S LDAE+E+ + + L ++ ++T ++V+
Sbjct: 1121 RGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTVVVA 1180
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
RLS +K D + V+K+G IVE G E LI +GG+++ +++
Sbjct: 1181 HRLSTIKNADVIAVVKNGVIVEKGTHETLINIEGGVYASLVQ 1222
>gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo sapiens]
>gi|8452823|gb|AAF75107.1|AF076775_1 (AF076775) MT-ABC
transporter [Homo sapiens] >gi|8547018|dbj|BAA96733.1|
(AB039371) mitochondrial ABC transporter 3 [Homo
sapiens] >gi|9187501|emb|CAB95766.2| (AJ289233) ABC
transporter umat [Homo sapiens]
Length = 842
Score = 256 bits (648), Expect = 4e-67
Identities = 175/588 (29%), Positives = 293/588 (49%), Gaps = 26/588 (4%)
Query: 3 KSINQLIRLLS-YL--RGHAVHFLIGLFLIILMSYT---NSIVPVLIRNAI----DKGVS 52
+ + +RLLS YL RG L+ L + LM N +VP+ RN + +K
Sbjct: 240 RDFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIVNLLTEKAPW 299
Query: 53 TGAYKVAIRYGLLILLVGV---LNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEME 109
Y L L G G S +L ++ Q+ + + F + +
Sbjct: 300 NSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIFSHLHELSLR 359
Query: 110 FFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVR-------MNITL 162
+ +G+++ T +T LS+ V ++ ++ III + Y + + L
Sbjct: 360 WHLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFNAWFGLIVFL 419
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
M +T+ IVV T + K R + Q + A ++ +T+K + E
Sbjct: 420 CMSLYLTLTIVV---TEWRTKFRRAMNT---QENATRARAVDSLLNFETVKYYNAESYEV 473
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAF 282
++ + + L K+ L LV+GL + + + L VG+ V F
Sbjct: 474 ERYREAIIKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLF 533
Query: 283 LTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFR 342
TY++ + PL G IQ + +FD++ + D P A + +G IEF
Sbjct: 534 GTYIIQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFE 593
Query: 343 DVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVN 402
+V +Y GR L+ VSF V PG+ + + GP G+GKS+IL+L+ RFY + G + IDG +
Sbjct: 594 NVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 653
Query: 403 VAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLP 462
++++ +LR + VPQ+ +FN +I +NI + A +EVE AA+ A IHD I + P
Sbjct: 654 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 713
Query: 463 KGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEIL 522
+GY T VGE+G+ LSGG++QR+A+AR +L P I+LLD+ S LD E+ + L ++
Sbjct: 714 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVC 773
Query: 523 QDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++T ++V+ RLS V D+++V+KDG IVE G+ E L+ +GG++++M
Sbjct: 774 ANRTTIVVAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADM 821
>dbj|BAB02129.1| (AP000386) P-glycoprotein; multi-drug resistance related; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1252
Score = 256 bits (648), Expect = 4e-67
Identities = 169/519 (32%), Positives = 269/519 (51%), Gaps = 10/519 (1%)
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTF-SGQL 119
RY L + +G++ S A + + + V LR A+ + ++ FFD +G +
Sbjct: 85 RYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVLKQDVGFFDTDARTGDI 144
Query: 120 ISRITNDTERITRFLSFRVRMLLY--SIFLIIISLYYMVRMNITLTMVALIT-IAIVVGL 176
+ ++ DT + +S +V ++ S FL + + ++ + L VA+I IA GL
Sbjct: 145 VFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLALLSVAVIPGIAFAGGL 204
Query: 177 NTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLN 236
YA + I K R IA IA ++T+ S E +S + L
Sbjct: 205 ---YAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALNAYSDAIQYTLKLG 261
Query: 237 VKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRAL 296
KA L + + ++ + +F+Y G I G+ + + L
Sbjct: 262 YKAGMAKGLGLGCTYGIACMSWALVFWYAGVFIRNGQTDGGKAFTAIFSAIVGGMSLGQS 321
Query: 297 GFTIGDIQRSLAAASRLFDVIDSAPKSI-DPPDAVEISNPRGEIEFRDVWLTYHTGRTVL 355
+G + AA +L ++I+ P I DP D + G IEF+DV +Y + V+
Sbjct: 322 FSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHGNIEFKDVTFSYPSRPDVM 381
Query: 356 KGVSFKV--KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
+F + G+ V + G GSGKS+++ LI RFY P G++L+DGV + ++ + LR+
Sbjct: 382 IFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQILLDGVEIKTLQLKFLRE 441
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ V QEP +F +I ENI KP+AT EVE AA A H FI LPKGYDT VGE+G
Sbjct: 442 QIGLVNQEPALFATTILENILYGKPDATMVEVEAAASAANAHSFITLLPKGYDTQVGERG 501
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+ LSGGQ+QRIA+ARAML +PKI+LLD+ S LDA +E + E L ++ +T ++V+ R
Sbjct: 502 VQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQEALDRVMVGRTTVVVAHR 561
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
L ++ VD + V++ G++VE G EELI K G ++ +++
Sbjct: 562 LCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLIR 600
Score = 229 bits (578), Expect = 6e-59
Identities = 146/504 (28%), Positives = 264/504 (51%), Gaps = 16/504 (3%)
Query: 76 FSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTF--SGQLISRITNDTERITRF 133
FS+ G L + +R AI R+E+ +FD+ S + +R+ D +
Sbjct: 752 FSIMGENLTTR--------VRRMMLSAILRNEVGWFDEDEHNSSLIAARLATDAADVKSA 803
Query: 134 LSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRH 193
++ R+ ++L ++ ++ S + ++++ L T ++V N + ++
Sbjct: 804 IAERISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLLVLANFAQQLSLKGFAGDTAK 863
Query: 194 QTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLV 253
+ IA ++ I+T+ + + + + + F E ++ + + L
Sbjct: 864 AHAKTSMIAGEGVSNIRTVAAFNAQSKILSLFCHELRVPQKRSLYRSQTSGFLFGLSQLA 923
Query: 254 LGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRL 313
L + + + +YG + + T +++ ++ + +I R A +
Sbjct: 924 LYGSEALILWYGAHLVSKGVSTFSKVIKVFVVLVITANSVAETVSLAPEIIRGGEAVGSV 983
Query: 314 FDVIDSAPKSIDPPDAVE--ISNPRGEIEFRDVWLTYHTGRTVL--KGVSFKVKPGEKVL 369
F V+D + IDP DA + RG+IEFR V Y + V+ + + +++ G
Sbjct: 984 FSVLDRQTR-IDPDDADADPVETIRGDIEFRHVDFAYPSRPDVMVFRDFNLRIRAGHSQA 1042
Query: 370 ITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSI 429
+ G GSGKSS++ +I RFY P G+V+IDG ++ ++ ++LR + V QEP +F +I
Sbjct: 1043 LVGASGSGKSSVIAMIERFYDPLAGKVMIDGKDIRRLNLKSLRLKIGLVQQEPALFAATI 1102
Query: 430 RENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARA 489
+NIA K AT+ EV AA+ A H FI+ LP+GY T VGE+G+ LSGGQ+QRIA+ARA
Sbjct: 1103 FDNIAYGKDGATESEVIDAARAANAHGFISGLPEGYKTPVGERGVQLSGGQKQRIAIARA 1162
Query: 490 MLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDG 549
+L NP ++LLD+ S LDAE+E L E L+ +++ +T ++V+ RLS ++ VD + V++DG
Sbjct: 1163 VLKNPTVLLLDEATSALDAESECVLQEALERLMRGRTTVVVAHRLSTIRGVDCIGVIQDG 1222
Query: 550 KIVEDGKPEELIKK-GGIFSEMMK 572
+IVE G EL+ + G +S +++
Sbjct: 1223 RIVEQGSHSELVSRPEGAYSRLLQ 1246
>gb|AAG33617.1|AF308472_1 (AF308472) ATP-binding cassette half-transporter [Homo sapiens]
Length = 896
Score = 256 bits (648), Expect = 4e-67
Identities = 175/588 (29%), Positives = 293/588 (49%), Gaps = 26/588 (4%)
Query: 3 KSINQLIRLLS-YL--RGHAVHFLIGLFLIILMSYT---NSIVPVLIRNAI----DKGVS 52
+ + +RLLS YL RG L+ L + LM N +VP+ RN + +K
Sbjct: 294 RDFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIVNLLTEKAPW 353
Query: 53 TGAYKVAIRYGLLILLVGV---LNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEME 109
Y L L G G S +L ++ Q+ + + F + +
Sbjct: 354 NSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIFSHLHELSLR 413
Query: 110 FFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVR-------MNITL 162
+ +G+++ T +T LS+ V ++ ++ III + Y + + L
Sbjct: 414 WHLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFNAWFGLIVFL 473
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
M +T+ IVV T + K R + Q + A ++ +T+K + E
Sbjct: 474 CMSLYLTLTIVV---TEWRTKFRRAMNT---QENATRARAVDSLLNFETVKYYNAESYEV 527
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAF 282
++ + + L K+ L LV+GL + + + L VG+ V F
Sbjct: 528 ERYREAIIKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLF 587
Query: 283 LTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFR 342
TY++ + PL G IQ + +FD++ + D P A + +G IEF
Sbjct: 588 GTYIIQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFE 647
Query: 343 DVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVN 402
+V +Y GR L+ VSF V PG+ + + GP G+GKS+IL+L+ RFY + G + IDG +
Sbjct: 648 NVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 707
Query: 403 VAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLP 462
++++ +LR + VPQ+ +FN +I +NI + A +EVE AA+ A IHD I + P
Sbjct: 708 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 767
Query: 463 KGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEIL 522
+GY T VGE+G+ LSGG++QR+A+AR +L P I+LLD+ S LD E+ + L ++
Sbjct: 768 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVC 827
Query: 523 QDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++T ++V+ RLS V D+++V+KDG IVE G+ E L+ +GG++++M
Sbjct: 828 ANRTTIVVAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADM 875
>pir||DVHY1C multidrug resistance protein 1 - Chinese hamster
>gi|191155|gb|AAA37004.1| (M59253) p-glycoprotein
[Cricetulus sp.]
Length = 1276
Score = 256 bits (647), Expect = 5e-67
Identities = 153/490 (31%), Positives = 266/490 (54%), Gaps = 7/490 (1%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI E+ +FD G+L +R+T+D +I + ++ M ++
Sbjct: 136 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMA 195
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 196 TFFGGFIIGFTRGWKLTLV-ILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEV 254
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ +++ EE L +K + A FL++ + + F+YG
Sbjct: 255 LAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYG 314
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
+I ++G+++ +L + + I + AA +F++ID+ P SID
Sbjct: 315 TSLVISKEYSIGQVLTVFFAVLIAPFSIGQASPNIEAFANARGAAYEIFNIIDNKP-SID 373
Query: 326 P--PDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSI 381
+ + N +G +EF+++ +Y + + V LKG++ KV+ G+ V + G G GKS+
Sbjct: 374 SFSKNGYKPDNIKGNLEFKNIHFSYPSRKDVQILKGLNLKVQSGQTVALVGNSGCGKSTT 433
Query: 382 LKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT 441
++L+ R Y PT+G V IDG ++ I LR+I+ V QEP +F +I ENI + N T
Sbjct: 434 VQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVT 493
Query: 442 QEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDD 501
+E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+LLD+
Sbjct: 494 MDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDE 553
Query: 502 PVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI 561
S LD E+E + L + + +T ++++ RLS V+ D + G IVE G EEL+
Sbjct: 554 ATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADIIAGFDGGVIVEQGNHEELM 613
Query: 562 KKGGIFSEMM 571
++ GI+ +++
Sbjct: 614 REKGIYFKLV 623
Score = 246 bits (621), Expect = 6e-64
Identities = 167/582 (28%), Positives = 305/582 (51%), Gaps = 29/582 (4%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYT--------NSIVPVLIRNAIDKGVSTGAYKVAIR 61
R+L +F++G+F I+ + +V V RN D+ T + +
Sbjct: 696 RILKLNSSEWPYFVVGIFCAIVNGALQPAFSIIFSKVVGVFTRNTDDE---TKRHDSNL- 751
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L++GV++ + + KA + LR F+++ R ++ +FD K +G L
Sbjct: 752 FSLLFLILGVISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGAL 811
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ ND ++ R+ ++ +I IIISL Y +TL ++A++ I + G
Sbjct: 812 TTRLANDAGQVKGATGARLAVITQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAG 869
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 870 VVEMKMLSGQALKDKKELEGS--GKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRN 927
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+K + + + ++ + + F +G + + +T ++ + ++ +
Sbjct: 928 ALKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQ 987
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT 353
+ D ++ +AS + +I+ P SID ++ + G ++F +V Y T
Sbjct: 988 VSSFAPDYAKAKVSASHIIMIIEKVP-SIDSYSTGGLKPNTLEGNVKFNEVVFNYPTRPD 1046
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VL+G++ +VK G+ + + G G GKS++++L+ RFY P G V +DG V ++ + L
Sbjct: 1047 IPVLQGLNLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEVNQLNVQWL 1106
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R + V QEP +F+ SI ENIA + +Q+E+ERAAK A IH FI SLP Y+T V
Sbjct: 1107 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRV 1166
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
G+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++
Sbjct: 1167 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1226
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS ++ D ++V+++GK+ E G ++L+ + GI+ M+
Sbjct: 1227 IAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMV 1268
>gb|AAA37005.1| (M59254) p-glycoprotein [Cricetulus sp.]
Length = 1169
Score = 256 bits (647), Expect = 5e-67
Identities = 153/490 (31%), Positives = 266/490 (54%), Gaps = 7/490 (1%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI E+ +FD G+L +R+T+D +I + ++ M ++
Sbjct: 29 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMA 88
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 89 TFFGGFIIGFTRGWKLTLV-ILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEV 147
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ +++ EE L +K + A FL++ + + F+YG
Sbjct: 148 LAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYG 207
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
+I ++G+++ +L + + I + AA +F++ID+ P SID
Sbjct: 208 TSLVISKEYSIGQVLTVFFAVLIAPFSIGQASPNIEAFANARGAAYEIFNIIDNKP-SID 266
Query: 326 P--PDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSI 381
+ + N +G +EF+++ +Y + + V LKG++ KV+ G+ V + G G GKS+
Sbjct: 267 SFSKNGYKPDNIKGNLEFKNIHFSYPSRKDVQILKGLNLKVQSGQTVALVGNSGCGKSTT 326
Query: 382 LKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT 441
++L+ R Y PT+G V IDG ++ I LR+I+ V QEP +F +I ENI + N T
Sbjct: 327 VQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVT 386
Query: 442 QEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDD 501
+E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+LLD+
Sbjct: 387 MDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDE 446
Query: 502 PVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI 561
S LD E+E + L + + +T ++++ RLS V+ D + G IVE G EEL+
Sbjct: 447 ATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADIIAGFDGGVIVEQGNHEELM 506
Query: 562 KKGGIFSEMM 571
++ GI+ +++
Sbjct: 507 REKGIYFKLV 516
Score = 246 bits (621), Expect = 6e-64
Identities = 167/582 (28%), Positives = 305/582 (51%), Gaps = 29/582 (4%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYT--------NSIVPVLIRNAIDKGVSTGAYKVAIR 61
R+L +F++G+F I+ + +V V RN D+ T + +
Sbjct: 589 RILKLNSSEWPYFVVGIFCAIVNGALQPAFSIIFSKVVGVFTRNTDDE---TKRHDSNL- 644
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L++GV++ + + KA + LR F+++ R ++ +FD K +G L
Sbjct: 645 FSLLFLILGVISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGAL 704
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ ND ++ R+ ++ +I IIISL Y +TL ++A++ I + G
Sbjct: 705 TTRLANDAGQVKGATGARLAVITQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAG 762
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 763 VVEMKMLSGQALKDKKELEGS--GKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRN 820
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+K + + + ++ + + F +G + + +T ++ + ++ +
Sbjct: 821 ALKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQ 880
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT 353
+ D ++ +AS + +I+ P SID ++ + G ++F +V Y T
Sbjct: 881 VSSFAPDYAKAKVSASHIIMIIEKVP-SIDSYSTGGLKPNTLEGNVKFNEVVFNYPTRPD 939
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VL+G++ +VK G+ + + G G GKS++++L+ RFY P G V +DG V ++ + L
Sbjct: 940 IPVLQGLNLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEVNQLNVQWL 999
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R + V QEP +F+ SI ENIA + +Q+E+ERAAK A IH FI SLP Y+T V
Sbjct: 1000 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRV 1059
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
G+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++
Sbjct: 1060 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1119
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS ++ D ++V+++GK+ E G ++L+ + GI+ M+
Sbjct: 1120 IAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMV 1161
>emb|CAA75922.1| (Y15990) P-glycoprotein-like protein [Arabidopsis thaliana]
Length = 1229
Score = 256 bits (647), Expect = 5e-67
Identities = 173/538 (32%), Positives = 284/538 (52%), Gaps = 17/538 (3%)
Query: 44 RNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAI 103
+N +K + KV +++ + L +G L F +++ Q A +R + I
Sbjct: 55 QNQSNKDIVEIVSKVCLKF--VYLGLGTLGAAFLEVACWMITGERQAA--RIRSLYLKTI 110
Query: 104 QRHEMEFFD-KTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITL 162
R ++ FFD +T +G+++ R++ DT I + +V + I + L
Sbjct: 111 LRQDIGFFDVETSTGEVVGRMSGDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGWLL 170
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
T+V L++I ++ + V + + +++ T+ I+T+ S + E+
Sbjct: 171 TLVMLVSIPLLAIAGAAMPIIVTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAM 230
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAF 282
+ + Y +VK L F V + + ++GG+ I++ T GE+V
Sbjct: 231 KSYREFINLAYRASVKQGFSMGLGLGVVFFVFFCSYALAIWFGGEMILKKGYTGGEVV-- 288
Query: 283 LTYMLTMMWPLRALGFT---IGDIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRG 337
M+T++ +LG T + AAA ++F+ I+ P SID D + + RG
Sbjct: 289 -NVMVTVVASSMSLGQTTPCLTAFAAGKAAAYKMFETIERKP-SIDAFDLNGKVLEDIRG 346
Query: 338 EIEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGE 395
EIE RDV +Y V G S + G + G GSGKSS++ LI RFY P+ G
Sbjct: 347 EIELRDVCFSYPARPMEEVFGGFSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGS 406
Query: 396 VLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIH 455
VLIDGVN+ + + + +R + V QEP +F+ SI ENI K NAT EE++ AAK+A
Sbjct: 407 VLIDGVNLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYGKENATVEEIQAAAKLANAA 466
Query: 456 DFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLV 515
+FI LP+G +T+VGE G LSGGQ+QRIA+ARA+L +P+I+LLD+ S LDAE+E+ +
Sbjct: 467 NFIDKLPRGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQ 526
Query: 516 EDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
E L ++ +T +IV+ RLS V+ D + V+ GKIVE+G EL+K G ++++++
Sbjct: 527 EALDRVMMSRTTVIVAHRLSTVRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLIR 584
Score = 245 bits (618), Expect = 1e-63
Identities = 155/522 (29%), Positives = 279/522 (52%), Gaps = 14/522 (2%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ ++ +L+GV + + YL A + +R+ F + E+ +FD + SG +
Sbjct: 704 WSMIFVLLGVASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTI 763
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
SR++ D I + + + + + + L + L ++ L+ I ++ G+N
Sbjct: 764 GSRLSADAALIKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLI-GINGY 822
Query: 180 YAMK-VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+K ++ + + + +A + I+T+ S EE V + + E+ +K
Sbjct: 823 LQIKFIKGFTADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIK 882
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELV-AFLTYMLTMMWPLRALG 297
I+ + F VL ++ FY G + + ++ FL +T + +A
Sbjct: 883 QGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTMTAIGISQASS 942
Query: 298 FTIGDIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRGEIEFRDVWLTYHTGRTV- 354
F D ++ AA+ +F +ID ID D + + N +G+IE + TY T V
Sbjct: 943 FA-PDSSKAKGAAASIFGIIDGK-SMIDSRDESGLVLENVKGDIELCHISFTYQTRPDVQ 1000
Query: 355 -LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
+ + F ++ G+ V + G GSGKS+++ L+ RFY P G + +D V + K++ + +R+
Sbjct: 1001 IFRDLCFAIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWVRQ 1060
Query: 414 IVAYVPQEPFIFNRSIRENIALAK--PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGE 471
+ V QEP +FN +IR NIA K A++ E+ AA++A H FI+S+ +GYDTVVGE
Sbjct: 1061 QMGLVGQEPVLFNDTIRSNIAYGKGGDEASEAEIIAAAELANAHGFISSIQQGYDTVVGE 1120
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
+GI LSGGQ+QR+A+ARA++ PKI+LLD+ S LDAE+E+ + + L ++ ++T ++V+
Sbjct: 1121 RGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTVVVA 1180
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
RLS +K D + V+K+G IVE G E LI +GG+++ +++
Sbjct: 1181 HRLSTIKNADVIAVVKNGVIVEKGTHETLINIEGGVYASLVQ 1222
>sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1)
>gi|191165|gb|AAA68883.1| (M60040) p-glycoprotein
isoform I [Cricetulus griseus]
Length = 1276
Score = 256 bits (646), Expect = 7e-67
Identities = 153/490 (31%), Positives = 266/490 (54%), Gaps = 7/490 (1%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI E+ +FD G+L +R+T+D +I + ++ M ++
Sbjct: 136 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMA 195
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 196 TFFGGFIIGFTRGWKLTLV-ILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEV 254
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ +++ EE L +K + A FL++ + + F+YG
Sbjct: 255 LAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYG 314
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
+I ++G+++ +L + + I + AA +F++ID+ P SID
Sbjct: 315 TSLVISKEYSIGQVLTVFFAVLIGAFSIGQASPNIEAFANARGAAYEIFNIIDNKP-SID 373
Query: 326 P--PDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSI 381
+ + N +G +EF+++ +Y + + V LKG++ KV+ G+ V + G G GKS+
Sbjct: 374 SFSKNGYKPDNIKGNLEFKNIHFSYPSRKDVQILKGLNLKVQSGQTVALVGNSGCGKSTT 433
Query: 382 LKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT 441
++L+ R Y PT+G V IDG ++ I LR+I+ V QEP +F +I ENI + N T
Sbjct: 434 VQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVT 493
Query: 442 QEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDD 501
+E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+LLD+
Sbjct: 494 MDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDE 553
Query: 502 PVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI 561
S LD E+E + L + + +T ++++ RLS V+ D + G IVE G EEL+
Sbjct: 554 ATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADIIAGFDGGVIVEQGNHEELM 613
Query: 562 KKGGIFSEMM 571
++ GI+ +++
Sbjct: 614 REKGIYFKLV 623
Score = 246 bits (621), Expect = 6e-64
Identities = 167/582 (28%), Positives = 305/582 (51%), Gaps = 29/582 (4%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYT--------NSIVPVLIRNAIDKGVSTGAYKVAIR 61
R+L +F++G+F I+ + +V V RN D+ T + +
Sbjct: 696 RILKLNSSEWPYFVVGIFCAIVNGALQPAFSIIFSKVVGVFTRNTDDE---TKRHDSNL- 751
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L++GV++ + + KA + LR F+++ R ++ +FD K +G L
Sbjct: 752 FSLLFLILGVISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGAL 811
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ ND ++ R+ ++ +I IIISL Y +TL ++A++ I + G
Sbjct: 812 TTRLANDAGQVKGATGARLAVITQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAG 869
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 870 VVEMKMLSGQALKDKKELEGS--GKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRN 927
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+K + + + ++ + + F +G + + +T ++ + ++ +
Sbjct: 928 ALKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQ 987
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT 353
+ D ++ +AS + +I+ P SID ++ + G ++F +V Y T
Sbjct: 988 VSSFAPDYAKAKVSASHIIMIIEKVP-SIDSYSTGGLKPNTLEGNVKFNEVVFNYPTRPD 1046
Query: 354 --VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
VL+G++ +VK G+ + + G G GKS++++L+ RFY P G V +DG V ++ + L
Sbjct: 1047 IPVLQGLNLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEVNQLNVQWL 1106
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R + V QEP +F+ SI ENIA + +Q+E+ERAAK A IH FI SLP Y+T V
Sbjct: 1107 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRV 1166
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
G+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++
Sbjct: 1167 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1226
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS ++ D ++V+++GK+ E G ++L+ + GI+ M+
Sbjct: 1227 IAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMV 1268
>sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2)
>gi|191167|gb|AAA68884.1| (M60041) p-glycoprotein
isoform II [Cricetulus griseus]
Length = 1276
Score = 256 bits (646), Expect = 7e-67
Identities = 160/500 (32%), Positives = 276/500 (55%), Gaps = 27/500 (5%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSI- 145
AA + +R F AI E+ +FD G+L +R+T+D +I + ++ M SI
Sbjct: 138 AAGRQINKIRQKFFHAIMNQEIGWFDVHDIGELNTRLTDDVSKINDGIGDKIGMFFQSIA 197
Query: 146 -FLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIA-SIAT 203
FL + ++ +TL ++A ++ ++GL++ KV + Q A ++A
Sbjct: 198 TFLAAFIVGFISGWKLTLVILA---VSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAE 254
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
+A I+T+ + + ++++ EE ++ +K + +L++ + + F+
Sbjct: 255 EVLAAIRTVIAFGGQNKELERYNKNLEEAKNVGIKKAVTANISIGIAYLLVYASYALAFW 314
Query: 264 YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ---RSLAAASRLFDVIDSA 320
YG ++ N +VG++ LT ++++ ++G +I+ + AA +F +ID+
Sbjct: 315 YGTSLVLSNEYSVGQV---LTVFFSILFGTFSIGHIAPNIEVFANARGAAYEIFKIIDNE 371
Query: 321 PKSIDP-------PDAVEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLIT 371
P SID PD+V G +EF++V +Y +G +LKG++ KV+ G+ V +
Sbjct: 372 P-SIDSFSTQGHKPDSV-----MGNLEFKNVHFSYPSRSGIKILKGLNLKVQSGQTVALV 425
Query: 372 GPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRE 431
G G GKS+ ++L+ R Y PT+G V IDG ++ I LR+I+ V QEP +F +I E
Sbjct: 426 GKSGCGKSTTVQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAE 485
Query: 432 NIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAML 491
NI + N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++
Sbjct: 486 NIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALV 545
Query: 492 MNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKI 551
NPKI+LLD+ S LD E+E + L + + +T ++++ RLS V+ D + G I
Sbjct: 546 RNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVI 605
Query: 552 VEDGKPEELIKKGGIFSEMM 571
VE G EEL+K+ GI+ ++
Sbjct: 606 VEQGNHEELMKEKGIYCRLV 625
Score = 238 bits (600), Expect = 2e-61
Identities = 157/526 (29%), Positives = 280/526 (52%), Gaps = 19/526 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ L L++G++ V + KA + LR F+++ R ++ +FD + +G L
Sbjct: 753 FSLFFLVMGMICFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHRNSTGAL 812
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ +D + +S R+ + ++ IIISL Y +TL +V + + I+ G
Sbjct: 813 TTRLASDAANVKGAMSSRLAGITQNVANLGTGIIISLVY--GWQLTLLLVVIAPLIILSG 870
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + V IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 871 MMEMKVLSGQALKDK--KELEVSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRN 928
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGE-LVAFLTYMLTMMWPLR 294
+K + + + ++ + + F +G + +T ++ F + +
Sbjct: 929 ALKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAHQIMTFENVMLVFSAVVFGAIAAGN 988
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP--RGEIEFRDVWLTYHTGR 352
A F D ++ +AS + +++ P SID + G ++F +V Y T
Sbjct: 989 ASSFA-PDYAKAKVSASHIIRIMEKIP-SIDSYSTRGLKPNWLEGNVKFNEVVFNYPTRP 1046
Query: 353 T--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTEN 410
VL+G+S +VK G+ + + G G GKS++++L+ RFY P G V +DG + ++ +
Sbjct: 1047 DIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQW 1106
Query: 411 LRKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTV 468
LR + V QEP +F+ SI ENIA + +Q+E+ERAAK A IH FI SLP Y+T
Sbjct: 1107 LRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTR 1166
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
VG+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T +
Sbjct: 1167 VGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCI 1226
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
+++ RLS ++ D ++V+++GK+ E G ++L+ + GI+ M++AG
Sbjct: 1227 VIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVQAG 1272
>pir||T40790 probable permease - fission yeast (Schizosaccharomyces pombe)
>gi|4760347|emb|CAB42370.1| (AL049769) putative permease
[Schizosaccharomyces pombe]
Length = 726
Score = 256 bits (646), Expect = 7e-67
Identities = 176/591 (29%), Positives = 303/591 (50%), Gaps = 33/591 (5%)
Query: 3 KSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY 62
K +N + RL + RG +F I L+++ S +P ++ +D G S+G V
Sbjct: 140 KKVN-VFRLFTLARGQGWNFFIAGSLLLVSSGVTMSIPYIVGKILDAG-SSGDSSVTH-- 195
Query: 63 GLLILLVGVLNGVF--SLAGRYLLVKAAQYA-VYYLRMDAFRAIQRHEMEFFDKTFS--- 116
++G+ +G F L G + L A + + LR+ + R + R F K S
Sbjct: 196 -----IMGIPSGTFYIGLLGLFFLGSACNFGRIITLRLLSERIVSRLRARLFAKCMSLDG 250
Query: 117 --------GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLT-MVAL 167
G LISR+T D+ + + LS + L S I + M+ +++ LT ++L
Sbjct: 251 AFFDFHKHGDLISRLTTDSSIVGKSLSMYLSDGLRSSVSAIAGIGMMLYVSMRLTGYMSL 310
Query: 168 ITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQ 227
I I +G Y VR + + G + ++ +A ++T ++ E +++
Sbjct: 311 IVPPIALGA-FFYGEYVRKLSRTTQDALGDLTRVSEEKLANVRTTQAFLGERQEVNRYND 369
Query: 228 ENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYML 287
L+ L + + ++ + + + + GG+ + +TVG+L +FL Y +
Sbjct: 370 YIRNLFVLAKREAFASGIFFGSTGFLGNATVIAILALGGRMVAAGDITVGQLSSFLLYTV 429
Query: 288 TMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGE--IEFRDVW 345
+ L DI + L AASRLF+++D+ PK I P + + G+ + FR+V
Sbjct: 430 YAGGSIVGLSGCFTDIMKGLGAASRLFELLDAKPK-IAPTVGIPVPVTVGKAILSFRNVG 488
Query: 346 LTYHT--GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNV 403
Y T ++ +SF + PG V I P G GKS+I +L+ RFY P+ G++L DGV++
Sbjct: 489 FAYPTRPSASIFDNLSFDIHPGTNVAIVAPSGGGKSTISQLLLRFYAPSSGKILADGVDI 548
Query: 404 AKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPK 463
+ R V QEP +F+ +I ENIA K NA+QEE+E AAK A F+ S P+
Sbjct: 549 STYNVHQWRSHFGLVGQEPVLFSGTIGENIAYGKSNASQEEIEDAAKRANC-SFVLSFPE 607
Query: 464 GYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ 523
+ T VG +G+ LSGGQ+QRIA+ARA+L NP ++LD+ S LD E E + + ++ ++
Sbjct: 608 KWSTQVGTRGLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMH 667
Query: 524 DK--TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
++ T + ++ +L+ ++ D++IV+ DGK++E G E L + G F ++M+
Sbjct: 668 NRSMTTITIAHKLATIRRADQIIVVGDGKVLEQGSFERLSRPGTNFYKLMR 718
>gb|AAF69007.1|AF257746_1 (AF257746) multidrug resistance protein 1a [Rattus norvegicus]
Length = 1272
Score = 256 bits (646), Expect = 7e-67
Identities = 155/494 (31%), Positives = 264/494 (53%), Gaps = 15/494 (3%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI E+ +FD G+L +R+T+D +I + ++ M ++
Sbjct: 131 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMA 190
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK ++A
Sbjct: 191 TFFGGFIIGFTRGWKLTLV-ILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEV 249
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ +++ EE L +K + A FL++ + + F+YG
Sbjct: 250 LAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYG 309
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP---- 321
+I T+G+++ +L + + I + AA +F +ID+ P
Sbjct: 310 TSLVISKEYTIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFSIIDNKPSIDS 369
Query: 322 --KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
KS PD N +G +EF+++ +Y + + V LKG++ KVK G+ V + G G G
Sbjct: 370 FSKSGHKPD-----NIQGNLEFKNIHFSYPSRKDVQILKGLNLKVKSGQTVALVGNSGCG 424
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAK 437
KS+ ++L+ R Y P +GEV IDG ++ I LR+I+ V QEP +F +I ENI +
Sbjct: 425 KSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGR 484
Query: 438 PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI+
Sbjct: 485 ENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKIL 544
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
LLD+ S LD E+E + L + + +T ++++ RLS V+ D + G IVE G
Sbjct: 545 LLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNH 604
Query: 558 EELIKKGGIFSEMM 571
+EL+++ GI+ +++
Sbjct: 605 DELMREKGIYFKLV 618
Score = 242 bits (610), Expect = 1e-62
Identities = 159/569 (27%), Positives = 299/569 (51%), Gaps = 25/569 (4%)
Query: 21 HFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR------YGLLILLVGVLNG 74
+F++G+F I+ ++ + GV T I+ + LL L++G+++
Sbjct: 702 YFVVGVFCAIINGGLQPAFSIIFSKVV--GVFTKNDTPEIQRQNSNLFSLLFLILGIISF 759
Query: 75 VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITR 132
+ + KA + LR F+++ R ++ +FD K +G L +R+ ND ++
Sbjct: 760 ITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDPKNTTGALTTRLANDAAQVKG 819
Query: 133 FLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
R+ ++ +I IIISL Y +TL ++A++ I + G+ + + +
Sbjct: 820 ATGSRLAVITQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAGVVEMKMLSGQALK 877
Query: 189 DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGN 248
DK + IAT I +T+ SL+ E+ +T ++Q + Y +K + + +
Sbjct: 878 DKKELEGS--GKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVFGITFS 935
Query: 249 APFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLA 308
++ + + F +G + + +T ++ + ++ + + D ++
Sbjct: 936 FTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKAKV 995
Query: 309 AASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKP 364
+AS + +I+ P+ ID + ++ + G ++F V Y T VL+G+S +VK
Sbjct: 996 SASHIIRIIEKIPE-IDSYSTEGLKPNMLEGNVKFNGVMFNYPTRPNIPVLQGLSLEVKK 1054
Query: 365 GEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI 424
G+ + + G G GKS++++L+ RFY P G V +DG + ++ + LR + V QEP +
Sbjct: 1055 GQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQWLRAHLGIVSQEPIL 1114
Query: 425 FNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQ 482
F+ SI ENIA + + EE+ +AAK A IH FI SLP+ Y+T VG+KG LSGGQ+Q
Sbjct: 1115 FDCSIAENIAYGDNSRVVSHEEIVKAAKEANIHQFIDSLPEKYNTRVGDKGTQLSGGQKQ 1174
Query: 483 RIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDR 542
RIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++++ RLS ++ D
Sbjct: 1175 RIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADL 1234
Query: 543 VIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++V+++G++ E G ++L+ + GI+ M+
Sbjct: 1235 IVVIQNGQVKEHGTHQQLLAQKGIYFSMV 1263
>sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1)
>gi|92489|pir||JH0502 p-glycoprotein - rat
Length = 1277
Score = 256 bits (646), Expect = 7e-67
Identities = 156/495 (31%), Positives = 268/495 (53%), Gaps = 17/495 (3%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI E+ +FD +G+L +R+T+D +I + ++ M SI
Sbjct: 138 AAGRQIHKIRQKFFHAIMNQEIGWFDVNDAGELNTRLTDDVSKINDGIGDKLGMFFQSIT 197
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIA-SIATGT 205
LT+V ++ ++ ++GL++ KV + Q A ++A
Sbjct: 198 TFSAGFIIGFISGWKLTLV-ILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEV 256
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ ++++ EE + +K + +L++ + + F+YG
Sbjct: 257 LAAIRTVIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYG 316
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
++ N ++G+++ +L + + L I + AA +F +ID+ P SID
Sbjct: 317 TSLVLSNEYSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEP-SID 375
Query: 326 P-------PDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGS 376
PD++ G +EF++V+ Y + V LKG++ KVK G+ V + G G
Sbjct: 376 SFSTKGHKPDSI-----MGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGC 430
Query: 377 GKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA 436
GKS+ ++L+ R Y P +GEV IDG ++ I LR+I+ V QEP +F +I ENI
Sbjct: 431 GKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYG 490
Query: 437 KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKI 496
+ N T +E+E+A K A +DFI LP +DT+VGE+G LSGGQ+QRIA+ARA++ NPKI
Sbjct: 491 RENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKI 550
Query: 497 VLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGK 556
+LLD+ S LD E+E + L + + +T ++++ RLS V+ D + G IVE G
Sbjct: 551 LLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGN 610
Query: 557 PEELIKKGGIFSEMM 571
EEL+K+ GI+ +++
Sbjct: 611 HEELMKEKGIYFKLV 625
Score = 239 bits (603), Expect = 7e-62
Identities = 153/528 (28%), Positives = 288/528 (53%), Gaps = 22/528 (4%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ LL L++G+++ V + KA + LR F+++ R ++ +FD K +G L
Sbjct: 753 FSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSL 812
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ +D + + R+ ++ ++ II+SL + +TL +V +I + ++ G
Sbjct: 813 TTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLGG 872
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + + IAT I +T+ SL+ E+ +T ++Q + Y
Sbjct: 873 IIEMKLLSGQALKDK--KELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRN 930
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+K + + ++ + + F +G + + +T ++ + +++ A
Sbjct: 931 ALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFS---AVVFGAMA 987
Query: 296 LGFTIG---DIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHT 350
G T D ++ +AS + +I+ P+ ID + ++ + G ++F V Y T
Sbjct: 988 AGNTSSFAPDYAKAKVSASHIIGIIEKIPE-IDSYSTEGLKPNWLEGNVKFNGVKFNYPT 1046
Query: 351 GRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
VL+G+SF+VK G+ + + G G GKS++++L+ RFY P G V +DG + ++
Sbjct: 1047 RPNIPVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNV 1106
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYD 466
+ +R + V QEP +F+ SI ENIA + + EE+ RAA+ A IH FI SLP+ Y+
Sbjct: 1107 QCVRAL-GIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYN 1165
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T VG+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T
Sbjct: 1166 TRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRT 1225
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++++ RLS ++ D ++V+++G++ E G ++L+ + GI+ M++AG
Sbjct: 1226 CVVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMVQAG 1273
>gb|AAB41963.1| (U60019) TAP1-b [Mus musculus] >gi|2555195|gb|AAB81534.1|
(AF027865) antigen processing transporter TAP1 [Mus
musculus]
Length = 724
Score = 255 bits (645), Expect = 9e-67
Identities = 171/579 (29%), Positives = 294/579 (50%), Gaps = 10/579 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
R + + L R+L +L + L L+IL +P D + R
Sbjct: 143 RDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAIPFFTGRITDWILQDKTVPSFTR 202
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
L+ ++ + + A + + + + FRA+ R E FF K +G + S
Sbjct: 203 NIWLMSILTIASTALEFASDGIYNITMGHMHGRVHREVFRAVLRQETGFFLKNPAGSITS 262
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+T DT + +S + +LL+ + + L +M + LT+V LI + ++ L
Sbjct: 263 RVTEDTANVCESISGTLSLLLWYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLG 322
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK-AM 240
+ + K++ +A ++ + T++S + EE KF Q+ EE+ +LN K A+
Sbjct: 323 KVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEAL 382
Query: 241 KITALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
A V G+ + + Y GG+ +I+ ++ G LV+F+ Y L ++ L
Sbjct: 383 AYVAEVWTTS--VSGMLLKVGILYLGGQLVIRGAVSSGNLVSFVLYQLQFTQAVQVLLSL 440
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKG 357
+Q+++ ++ ++F+ +D P S ++ SN +G +EF+DV Y V L+G
Sbjct: 441 YPSMQKAVGSSEKIFEYLDRTPCS-PLSGSLAPSNMKGLVEFQDVSFAYPNQPKVQVLQG 499
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
++F + PG + GP GSGKS++ L+ Y+PT G++L+DG + + L VA
Sbjct: 500 LTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQCLVQYDHHYLHTQVAA 559
Query: 418 VPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
V QEP +F RS RENIA T EE+ A + HDFI+ P+GYDT VGE G L
Sbjct: 560 VGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDFISGFPQGYDTEVGETGNQL 619
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRL 534
SGGQRQ +ALARA++ P +++LDD S LDA + ++ L E + +T L+++Q+L
Sbjct: 620 SGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQL 679
Query: 535 SLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
SL + ++ +++G + E G +L+K+GG + M++A
Sbjct: 680 SLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEA 718
>dbj|BAB10822.1| (AB019223) multidrug resistance p-glycoprotein [Arabidopsis
thaliana]
Length = 1248
Score = 255 bits (645), Expect = 9e-67
Identities = 175/558 (31%), Positives = 300/558 (53%), Gaps = 27/558 (4%)
Query: 27 FLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVK 86
F+ ILM ++ + + K VS KVA+++ L GV++ F +++
Sbjct: 51 FMSILMGQLINVFGFSDHDHVFKEVS----KVAVKFLYLAAYAGVVS--FLQVSCWMVTG 104
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFD-KTFSGQLISRITNDTERITRFLSFRVRML--LY 143
Q +R + I R ++ FFD +T +G++I R++ DT I + +V L
Sbjct: 105 ERQST--RIRRLYLKTILRQDIGFFDTETNTGEVIGRMSGDTILIQDSMGEKVGKFTQLV 162
Query: 144 SIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRH-QTGVIASIA 202
S F+ ++ ++V M +TL ++ + + + G TY M + ++ + + G + A
Sbjct: 163 SSFVGGFTVAFIVGMKLTLALLPCVPLIVGTGGAMTYIMSKKAQRVQLAYTEAGNVVQQA 222
Query: 203 TGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMF 262
G+I +T+ + + E+ K+ ++ E Y VK + L +V+
Sbjct: 223 VGSI---RTVVAFTGEKQSMGKYEKKLEIAYKSMVKQGLYSGLGIGIMMVVVYCTYGFAI 279
Query: 263 YYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK 322
+YG + II+ T G+++ +T +LT L ++ AAA ++F+ I PK
Sbjct: 280 WYGARQIIEKGYTGGQVMNVITSILTGGMALGQTLPSLNSFAAGTAAAYKMFETIKRKPK 339
Query: 323 SIDPPDAVEISNP-----RGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPG 375
DA ++S +G+IE RDV+ Y V G S V G V + G G
Sbjct: 340 I----DAYDMSGEVLEEIKGDIELRDVYFRYPARPDVQIFVGFSLTVPNGMTVALVGQSG 395
Query: 376 SGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIAL 435
SGKS+++ LI RFY P GEVLIDG+++ K + + +R + V QEP +F +IRENI
Sbjct: 396 SGKSTVISLIERFYDPESGEVLIDGIDLKKFQVKWIRSKIGLVSQEPILFATTIRENIVY 455
Query: 436 AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPK 495
K +A+ +E+ A K+A +FI LP+G +T+VGE G LSGGQ+QRIA+ARA+L NPK
Sbjct: 456 GKKDASDQEIRTALKLANASNFIDKLPQGLETMVGEHGTQLSGGQKQRIAIARAILKNPK 515
Query: 496 IVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDG 555
I+LLD+ S LDAE+E+ + + L +++ +T ++V+ RL+ ++ D + V++ GK++E G
Sbjct: 516 ILLLDEATSALDAESERIVQDALVKLMLSRTTVVVAHRLTTIRTADMIAVVQQGKVIEKG 575
Query: 556 KPEELIK-KGGIFSEMMK 572
+E+IK G +S++++
Sbjct: 576 THDEMIKDPEGTYSQLVR 593
Score = 243 bits (614), Expect = 4e-63
Identities = 161/525 (30%), Positives = 282/525 (53%), Gaps = 23/525 (4%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ L+ + +G+ + + YL A + +R +F + ++ +FD K SG +
Sbjct: 725 WALIFVALGLTDLIVIPLQNYLFAIAGAKLIKRIRSLSFDRVLHQDISWFDDTKNSSGVI 784
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R++ D + + + +++ ++ II + N L ++AL+ +A V+
Sbjct: 785 GARLSTDASTVKSIVGDVLGLIMQNMATIIGAFIIAFTANWLLALMALL-VAPVMFFQGY 843
Query: 180 YAMK-VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
Y +K + K R + + +A+ ++ I+T+ S E+ V + ++ +E K
Sbjct: 844 YQIKFITGFGAKARGKYEEASQVASDAVSSIRTVASFCAEDKVMDLYQEKCDEPKQQGFK 903
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNT-LTVGELVAFLTYMLTMMWPLRALG 297
++ L +L L + S F GG +IQN T GE + + L A+G
Sbjct: 904 LGLVSGLCYGGSYLALYVIESVCFL-GGSWLIQNRRATFGEF-----FQVFFALTLTAVG 957
Query: 298 FT-----IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP--RGEIEFRDVWLTY-- 348
T DI ++ +A+ +FD++DS PK ID P G+IE + V Y
Sbjct: 958 VTQTSTMAPDINKAKDSAASIFDILDSKPK-IDSSSEKGTILPIVHGDIELQHVSFRYPM 1016
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
+ + + G+ V + G GSGKS+++ L+ RFY P G++L+D V + +K
Sbjct: 1017 RPDIQIFSDLCLTISSGQTVALVGESGSGKSTVISLLERFYDPDSGKILLDQVEIQSLKL 1076
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAK-PNATQEEVERAAKIAKIHDFIASLPKGYDT 467
LR+ + V QEP +FN +I NIA K AT+EE+ AAK A +H+FI+SLP+GY+T
Sbjct: 1077 SWLREQMGLVSQEPVLFNETIGSNIAYGKIGGATEEEIITAAKAANVHNFISSLPQGYET 1136
Query: 468 VVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTA 527
VGE+G+ LSGGQ+QRIA+ARA+L +PKI+LLD+ S LDAE+E+ + + L +++ ++T
Sbjct: 1137 SVGERGVQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERVVQDALDQVMVNRTT 1196
Query: 528 LIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMM 571
++V+ L+ +K D + V+K+G I E G+ E L++ GG ++ ++
Sbjct: 1197 VVVAHLLTTIKDADMIAVVKNGVIAESGRHETLMEISGGAYASLV 1241
>gi|6981354 P-glycoprotein 3/ multidrug resistance 2 [Rattus norvegicus]
>gi|1170903|sp|Q08201|MDR2_RAT MULTIDRUG RESISTANCE
PROTEIN 2 (P-GLYCOPROTEIN 2) >gi|543425|pir||S41646
p-glycoprotein - rat >gi|310193|gb|AAA02937.1| (L15079)
P-glycoprotein [Rattus norvegicus]
Length = 1278
Score = 255 bits (644), Expect = 1e-66
Identities = 155/495 (31%), Positives = 261/495 (52%), Gaps = 17/495 (3%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA + +R F AI R EM +FD + +L +R+T+D +I+ + +V M +I
Sbjct: 138 AAGRQIRKIRQKFFHAILRQEMGWFDIKGTTELNTRLTDDISKISEGIGDKVGMFFQAIA 197
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I ++GL+T K+ + DK ++A
Sbjct: 198 TFFAGFIVGFIRGWKLTLV-IMAITAILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEA 256
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+ I+T+ + + ++ + E + +K + FL++ + + F+YG
Sbjct: 257 LGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYG 316
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
+I T+G + +L + + I + AA +FD+ID+ PK ID
Sbjct: 317 STLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFPNARGAAYVIFDIIDNNPK-ID 375
Query: 326 P-------PDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGS 376
PD++ +G +EF DV +Y + + LKG++ KVK G+ V + G G
Sbjct: 376 SFSERGHKPDSI-----KGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGC 430
Query: 377 GKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA 436
GKS+ ++L+ R Y PT+G + IDG ++ LR+ + V QEP +F+ +I ENI
Sbjct: 431 GKSTTVQLLQRLYDPTEGTISIDGQDIRNFNVRCLREFIGVVSQEPVLFSTTIAENIRYG 490
Query: 437 KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKI 496
+ N T +E+++A K A +DFI LP+ +DT+VG++G LSGGQ+QRIA+ARA++ NPKI
Sbjct: 491 RGNVTMDEIKKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKI 550
Query: 497 VLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGK 556
+LLD+ S LD E+E ++ L + + +T ++++ RLS V+ D + +DG IVE G
Sbjct: 551 LLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGS 610
Query: 557 PEELIKKGGIFSEMM 571
ELIKK GI+ ++
Sbjct: 611 HSELIKKEGIYFRLV 625
Score = 227 bits (573), Expect = 2e-58
Identities = 155/526 (29%), Positives = 271/526 (51%), Gaps = 25/526 (4%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ L+ L +GV + + KA + LR AF+A+ R +M +FD K +G L
Sbjct: 753 FSLVFLGLGVHSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGAL 812
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ D ++ R+ ++ + IIIS Y +TL +++++ V G
Sbjct: 813 STRLATDAAQVQGATGTRLALIAQNTANLGTGIIISFIY--GWQLTLLLLSVVPFIAVAG 870
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + DK + IAT I I+T+ SL+ E ++ + ++ Y
Sbjct: 871 IVEMKMLAGNAKRDKKEMEAA--GKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRN 928
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+V+ I + + + + + F +G I+ + +++ + ++ L
Sbjct: 929 SVRKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGH 988
Query: 296 LGFTIGDIQRSLAAASRLFDV------IDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYH 349
D ++ +A+ LF + IDS + PD E G + F +V Y
Sbjct: 989 ASSFAPDYAKAKLSAAYLFSLFERQPLIDSYSREGMWPDKFE-----GSVTFNEVVFNYP 1043
Query: 350 TGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIK 407
T V L+G+S +VK G+ + + G G GKS++++L+ RFY P G VL+DG K+
Sbjct: 1044 TRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVLLDGQEAKKLN 1103
Query: 408 TENLRKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGY 465
+ LR + V QEP +F+ SI +NIA + +Q+E+ RAAK A IH FI +LP+ Y
Sbjct: 1104 VQWLRAQLGIVSQEPILFDCSIAKNIAYGDNSRVVSQDEIVRAAKEANIHPFIETLPQKY 1163
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
+T VG+KG LSGGQ+QRIA+ARA++ P+++LLD+ S LD E+EK + E L + + +
Sbjct: 1164 ETRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGR 1223
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
T ++++ RLS ++ D ++V+ +GK+ E G ++L+ + GI+ M+
Sbjct: 1224 TCIVIAHRLSTIQNADLIVVIDNGKVKEHGTHQQLLAQKGIYFSMV 1269
>gb|AAD01950.1| (AF033015) ABC transporter homolog Z [Listeria monocytogenes]
Length = 590
Score = 255 bits (644), Expect = 1e-66
Identities = 156/584 (26%), Positives = 290/584 (48%), Gaps = 19/584 (3%)
Query: 3 KSINQLIRLL-SYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDK-----------G 50
K Q+ R YLRG+ + L ++ +Y P I NA+ + G
Sbjct: 2 KEFKQISRFFWHYLRGYKPQLFVILIAVVFATYLQVKAPQYIGNAVQELGDYVVNLMQTG 61
Query: 51 VSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEF 110
V + + I + +++L VL + ++ A + +R+ FR +++ + F
Sbjct: 62 VDDKSDFIHIIW--MLILCYVLLAAATFIQSIIMTGVAGKSTNRMRIGLFRKMEKLSIRF 119
Query: 111 FDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITI 170
FD G+++SR T+D + I+ L+ + +L ++ L+I + M + N+ L V LI+
Sbjct: 120 FDSRNDGEMLSRFTSDLDNISNTLNQALIQVLSNVALMIGVIIMMFQQNVELAFVTLISA 179
Query: 171 AIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE 230
+ + T K R D + + GV+ I+G K I + +EE F ++N
Sbjct: 180 PFAIIIATVIIRKARKFVDIQQDELGVLNGYIDEKISGQKIIITNGLEEETIDGFVKQNN 239
Query: 231 ELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGG----KAIIQNTLTVGELVAFLTYM 286
+ + K + L + L + + ++GG ++ T +G +V F+ Y
Sbjct: 240 IVKNATYKGQVYSGLLFPMMQGISLLNTAIVIFFGGWLALNGDLERTAALGLIVMFVQYS 299
Query: 287 LTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWL 346
PL + +Q ++ A R+ +V + + ++ + I ++ V
Sbjct: 300 QQFYMPLTQISSQYSLLQLAITGARRVSEVF-AEEEEVERENLQTIDGINKGVKLDHVDF 358
Query: 347 TYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
Y + VLK VS V G+ V + GP GSGK++++ L+ RFY G +L D +++ I
Sbjct: 359 AYDPAKPVLKDVSIDVSKGKMVALVGPTGSGKTTVMNLLNRFYNVDGGAILFDDIDIRDI 418
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
+ ++LRK V V Q+ +F +IR+NI KP A+ +EV AAK A IHDFI +L KGY+
Sbjct: 419 RLDSLRKQVGIVLQDSVLFTGTIRDNIVFGKPEASDDEVINAAKQANIHDFIMNLEKGYE 478
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T + ++ S GQ+Q +++AR ++ NP +++LD SN+D TE ++ + + ++ +T
Sbjct: 479 TEISDENNIFSVGQKQLMSIARTIITNPSLLILDGATSNVDTVTESRIQKAMDNVISGRT 538
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+ +++ RL + D ++V+ G+++E G +EL+K G +SE+
Sbjct: 539 SFVIAHRLKTILDADHIVVLHQGEVIEQGNHDELMKAEGFYSEL 582
>pir||A75282 ABC transporter, ATP-binding protein, MsbA family - Deinococcus
radiodurans (strain R1)
>gi|6460192|gb|AAF11923.1|AE002068_6 (AE002068) ABC
transporter, ATP-binding protein, MsbA family
[Deinococcus radiodurans]
Length = 588
Score = 254 bits (643), Expect = 2e-66
Identities = 141/481 (29%), Positives = 253/481 (52%), Gaps = 1/481 (0%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
+R D F +Q+ F+D +GQL+SR+T D I L ++ +
Sbjct: 106 MRRDLFAHLQKLPFGFYDTHRTGQLMSRVTGDLYDIGELAHHGPEDLFIALVSFVGVFVI 165
Query: 155 MVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKS 214
+ +N+ LT++ L + + + +++ + R + G + + ++AGI+ ++S
Sbjct: 166 LAGLNLPLTLILLAFLPFMAAYALYFNVQLNRALLQSRQRIGEVNAQVEDSLAGIRVVQS 225
Query: 215 LSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTL 274
+ E +F N+ + + GL + +GG AI+Q L
Sbjct: 226 FTGEGTEARRFGAANDLFVEGRRGEYRAELYFYQGMTAFTGLMTIAVLMFGGWAILQGGL 285
Query: 275 TVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISN 334
+ LV +L + ++ P+R L +Q + R +++ P +D P A E+ N
Sbjct: 286 RIDGLVTYLMCVGILLEPIRRLVNLARVLQEGVTGFQRFREMMAVTPDIVDAPGAAELQN 345
Query: 335 PRGEIEFRDVWLTYHTGRT-VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTK 393
RGE+EF+ V Y VL+ ++ K++ GE V + G G GKS++ LI RFY +
Sbjct: 346 VRGEVEFQGVSFGYSPDAPPVLRDLNLKIRAGEFVALVGASGVGKSTLCALIPRFYDVSA 405
Query: 394 GEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAK 453
G+VL+DG +V + +LR+ V V Q+ ++F+ ++ ENI +P AT+ E AA+ A
Sbjct: 406 GQVLVDGHDVCGVTLASLRRSVGVVQQDVYLFSGTVMENIRYGRPGATEAEAMDAARQAG 465
Query: 454 IHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKK 513
HDFI LP+GY T +G++G+ LSGGQ+QR+++AR L +P I++ D+ S+LD E+E+
Sbjct: 466 AHDFITRLPQGYHTDIGQRGVKLSGGQKQRLSIARVFLKDPPILIFDEATSSLDNESERL 525
Query: 514 LVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ E L+ + + +T L+++ RLS V+ R++V+ + + E+G EL+ GG ++ +
Sbjct: 526 VQESLERLARRRTTLVIAHRLSTVRNAHRIVVLTENGVAEEGSHAELLALGGEYARLQAL 585
Query: 574 G 574
G
Sbjct: 586 G 586
>pir||T48007 P-glycoprotein homolog T17J13.110 [similarity] - Arabidopsis
thaliana >gi|6899925|emb|CAB71875.1| (AL138651)
P-glycoprotein-like proetin [Arabidopsis thaliana]
Length = 1292
Score = 254 bits (643), Expect = 2e-66
Identities = 169/554 (30%), Positives = 285/554 (50%), Gaps = 11/554 (1%)
Query: 25 GLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLL 84
GL I+ ++ V +N VS KVA+++ + L +G L +++
Sbjct: 91 GLGFPIMTILFGDVIDVFGQNQNSSDVSDKIAKVALKF--VYLGLGTLVAALLQVSGWMI 148
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFD-KTFSGQLISRITNDTERITRFLSFRVRMLLY 143
Q +R + I R ++ FFD +T +G+++ R++ DT I + +V +
Sbjct: 149 SGERQAG--RIRSLYLQTILRQDIAFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKAIQ 206
Query: 144 SIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIAT 203
+ I LT+V + +I ++V A+ + + + + A +
Sbjct: 207 LVSTFIGGFVIAFTEGWLLTLVMVSSIPLLVMSGAALAIVISKMASRGQTSYAKAAVVVE 266
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
T+ I+T+ S + E+ + +++ Y V T L +V+ + +
Sbjct: 267 QTVGSIRTVASFTGEKQAISNYNKHLVSAYRAGVFEGASTGLGLGTLNIVIFCTYALAVW 326
Query: 264 YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKS 323
YGGK I++ T G+++ + +LT L + AAA ++F+ I P+
Sbjct: 327 YGGKMILEKGYTGGQVLIIIFAVLTGSMSLGQASPCLSAFAAGQAAAYKMFEAIKRKPE- 385
Query: 324 IDPPDAVE--ISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLITGPPGSGKS 379
ID D + + RG+IE +V +Y + +G S + G V + G GSGKS
Sbjct: 386 IDASDTTGKVLDDIRGDIELNNVNFSYPARPEEQIFRGFSLSISSGSTVALVGQSGSGKS 445
Query: 380 SILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPN 439
+++ LI RFY P GEV IDG+N+ + + + +R + V QEP +F SI+ENIA K N
Sbjct: 446 TVVSLIERFYDPQSGEVRIDGINLKEFQLKWIRSKIGLVSQEPVLFTSSIKENIAYGKEN 505
Query: 440 ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLL 499
AT EE+ +A ++A FI LP+G DT+VGE G LSGGQ+QRIA+ARA+L +P+I+LL
Sbjct: 506 ATVEEIRKATELANASKFIDKLPQGLDTMVGEHGTQLSGGQKQRIAVARAILKDPRILLL 565
Query: 500 DDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEE 559
D+ S LDAE+E+ + E L I+ ++T ++V+ RLS V+ D + V+ GKIVE G E
Sbjct: 566 DEATSALDAESERIVQEALDRIMVNRTTVVVAHRLSTVRNADMIAVIHQGKIVEKGSHSE 625
Query: 560 LIK-KGGIFSEMMK 572
L++ G +S++++
Sbjct: 626 LLRDPEGAYSQLIR 639
Score = 241 bits (608), Expect = 2e-62
Identities = 156/520 (30%), Positives = 281/520 (54%), Gaps = 15/520 (2%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKT--FSGQL 119
+ ++ +L+GV + V A A V +R F + R E+ +FD+T SG +
Sbjct: 772 WAIIFMLLGVASMVVFPAQTIFFSIAGCKLVQRIRSMCFEKVVRMEVGWFDETENSSGAI 831
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R++ D + + + + ++ + L + L + L + ++ GLN
Sbjct: 832 GARLSADAATVRGLVGDALAQTVQNLASVTAGLVIAFVASWQLAFIVLAMLPLI-GLNGY 890
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
MK + + +A+ A G+I +T+ S EE V + ++ E ++
Sbjct: 891 IYMKFMVGFSADAKEASQVANDAVGSI---RTVASFCAEEKVMKMYKKKCEGPMRTGIRQ 947
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
++ + F VL + + FY G + ++ + T + V + + LTM + +
Sbjct: 948 GIVSGIGFGVSFFVLFSSYAASFYAGAR-LVDDGKTTFDSVFRVFFALTMAAVAISQSSS 1006
Query: 300 IG-DIQRSLAAASRLFDVIDSAPKSIDPPDAVE--ISNPRGEIEFRDVWLTYHTGRTV-- 354
+ D ++ AA+ +F VID K IDP D + N +G+IE R + Y + V
Sbjct: 1007 LSPDSSKASNAAASIFAVIDRESK-IDPSDESGRVLDNVKGDIELRHISFKYPSRPDVQI 1065
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
+ + ++ G+ + + G GSGKS+++ L+ RFY P G++ +DGV + ++ + LR+
Sbjct: 1066 FQDLCLSIRAGKTIALVGESGSGKSTVIALLQRFYDPDSGQITLDGVEIKTLQLKWLRQQ 1125
Query: 415 VAYVPQEPFIFNRSIRENIALAKP-NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
V QEP +FN +IR NIA K +AT+ E+ AA+++ H FI+ L +GYDT+VGE+G
Sbjct: 1126 TGLVSQEPVLFNETIRANIAYGKGGDATETEIVSAAELSNAHGFISGLQQGYDTMVGERG 1185
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+ LSGGQ+QR+A+ARA++ +PK++LLD+ S LDAE+E+ + + L ++ ++T ++V+ R
Sbjct: 1186 VQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRVMVNRTTVVVAHR 1245
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
LS +K D + V+K+G IVE GK E LI K G+++ +++
Sbjct: 1246 LSTIKNADVIAVVKNGVIVEKGKHETLINIKDGVYASLVQ 1285
>gb|AAC44070.1| (U51197) unknown [Sphingomonas sp. S88]
Length = 728
Score = 254 bits (642), Expect = 2e-66
Identities = 164/558 (29%), Positives = 286/558 (50%), Gaps = 3/558 (0%)
Query: 22 FLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGR 81
FL L + + ++ P+L ++ IDK + + L V V
Sbjct: 169 FLEVLGITLALNLLGLAAPLLFQSVIDKVLVHNSMSTLSVLAFAFLAVSVWEVALGWIRT 228
Query: 82 YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRML 141
L + Q L F + + +F+K G ++R+ E I FL+ +
Sbjct: 229 RLFTETTQKIDVELGARLFHHLLALPLGYFEKRRVGDTVTRV-RQLETIREFLTNASLTV 287
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
+ ++ L M+ + L V ++++ ++ A +R + ++ ++
Sbjct: 288 MVDPLFTVVFLGAMLFYSPMLFGVVIVSLVAYAMVSFGVAGPLRTRVEDKFEKSSASNAL 347
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTM 261
+++GI TIK+ +VE + Q ++ ++ + + + + + A L+ L+ + +
Sbjct: 348 LVESVSGIHTIKATAVEPHWQNRWERQLAAYTASSQRLINVANTGSQAIELISKLSFAAI 407
Query: 262 FYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP 321
++G KA+I ++VG LVAF + + P+ + D Q+ A RL DV++ P
Sbjct: 408 LFFGAKAVIGGAMSVGALVAFNMFAQRVSGPVIRMAQLWQDFQQVRIAIERLGDVLNH-P 466
Query: 322 KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-VLKGVSFKVKPGEKVLITGPPGSGKSS 380
P A + RG I F +V Y + VL ++ + G + I G GSGKS+
Sbjct: 467 VEPRPASAATLPVLRGAIRFENVTFRYAEDQPPVLSDITLDIPAGTSLGIVGSSGSGKST 526
Query: 381 ILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNA 440
+ KL+ R P G VL+D V+VA++ LR+ + V QE +F+RSIRENIAL+ P
Sbjct: 527 LAKLLQRLNTPDLGRVLVDEVDVAQLDPAWLRRQIGVVLQENLLFSRSIRENIALSNPAM 586
Query: 441 TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLD 500
E V AA +A HDFI P+GYDT + E+G+ LSGGQRQR+A+ARA++ NP+I++ D
Sbjct: 587 PFEHVVAAATLAGAHDFILRQPRGYDTEIVERGVNLSGGQRQRLAIARALVGNPRILVFD 646
Query: 501 DPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEEL 560
+ S LDAE+E+ + +L+ I +T +I++ RLS V+ DR+I ++ G+IVE G+ +EL
Sbjct: 647 EATSALDAESEELIQNNLRAISAGRTLVIIAHRLSAVRACDRIITLEQGRIVESGRHDEL 706
Query: 561 IKKGGIFSEMMKAGGVYG 578
++ GG ++++ + YG
Sbjct: 707 LRLGGRYADLHRRQSGYG 724
>emb|CAA42178.1| (X59615) HAM-1 [Mus musculus]
Length = 577
Score = 254 bits (641), Expect = 3e-66
Identities = 156/483 (32%), Positives = 263/483 (54%), Gaps = 10/483 (2%)
Query: 98 DAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVR 157
+ FRA+ R E FF K +G + SR+T DT + +S + +LL+ + + L +M
Sbjct: 92 EVFRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISDTLSLLLWYLGRALCLLVFMFW 151
Query: 158 MNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSV 217
+ LT+V LI + ++ L + + K++ +A ++ + T++ +
Sbjct: 152 GSPYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVALEALSAMPTVRQFAN 211
Query: 218 EENVQTKFSQENEELYSLNVK-AMKITALYGNAPFLVLGLAMST-MFYYGGKAIIQNTLT 275
EE KF Q+ EE+ +LN K A+ A V G+ + + Y GG+ +I+ T++
Sbjct: 212 EEGEAQKFRQKLEEMKTLNKKEALAYVAEVWTTS--VSGMLLKVGILYLGGQLVIRGTVS 269
Query: 276 VGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP 335
G LV+F+ Y L ++ L +Q+++ ++ ++F+ +D P S ++ SN
Sbjct: 270 SGNLVSFVLYQLQFTQAVQVLLSLYPSMQKAVGSSEKIFEYLDRTPCS-PLSGSLAPSNM 328
Query: 336 RGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTK 393
+G +E +DV Y V L+G++F + PG + GP GSGKS++ L+ Y+PT
Sbjct: 329 KGLVELQDVSFAYPNQPKVQVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTG 388
Query: 394 GEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIA 452
G++L+DG + + L VA V QEP +F RS RENIA T EE+ A +
Sbjct: 389 GQLLLDGQRLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVES 448
Query: 453 KIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEK 512
HDFI+ P+GYDT VGE G LSGGQRQ +ALARA++ P +++LDD S LDA +
Sbjct: 449 GAHDFISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPLLLILDDATSALDAGNQL 508
Query: 513 KLVEDLKEILQ--DKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++ L E + +T L+++Q+LSL + ++ +++G + E G +L+K+GG + M
Sbjct: 509 RVQRLLYESPKRASRTVLLITQQLSLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAM 568
Query: 571 MKA 573
++A
Sbjct: 569 VEA 571
>emb|CAA08835.1| (AJ009799) ABC transporter protein [Gallus gallus]
Length = 1288
Score = 254 bits (641), Expect = 3e-66
Identities = 151/489 (30%), Positives = 268/489 (53%), Gaps = 5/489 (1%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA V +R F AI R E+ +FD +G+L +R+ +D +I + ++ L+ S
Sbjct: 147 AAGRQVKKIREKFFHAIMRQEIGWFDVNDAGELNTRLIDDVSKINEGIGDKIGFLIQSET 206
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
+ LT+V ++ ++ V+GL+ K+ + DK + ++A
Sbjct: 207 TFLTGFIVGFIRGWKLTLV-ILAVSPVLGLSAALWAKILTAFTDKEQAAYAKAGAVAEEV 265
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
++ ++T+ + +E ++ + E+ + ++ + + A FL++ + + F+YG
Sbjct: 266 LSAVRTVIAFGGQEKEIKRYHKNLEDAKRIGIRKAITSNISMGAAFLLIYASYALAFWYG 325
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID 325
I+ N ++G ++ +L + + +I + AA +F++ID+ P+
Sbjct: 326 TTLILANEYSIGNVLTVFFSVLIGAFSIGQTAPSIEAFANARGAAYAIFNIIDNEPEIDS 385
Query: 326 PPDAV-EISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSIL 382
DA + + +G +EF++V+ Y + V LKG++ KV G+ V + G G GKS+ +
Sbjct: 386 YSDAGHKPDHIKGNLEFQNVFFNYPSRPDVEILKGLNLKVNCGQTVALVGGSGCGKSTTV 445
Query: 383 KLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQ 442
+LI RFY P +G + IDG ++ + LR+I+ V QEP +F +I ENI + + T
Sbjct: 446 QLIQRFYDPKEGTITIDGQDLKSLNVRYLREIIGVVNQEPVLFATTIAENIRYGREDVTM 505
Query: 443 EEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
EE+ERA K A +DFI LPK ++TVVGE+G +SGGQ+QRIA+ARA++ NPKI+LLD+
Sbjct: 506 EEIERATKEANAYDFIMKLPKKFETVVGERGAQMSGGQKQRIAIARALVHNPKILLLDEA 565
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK 562
S LD E+E + L + + +T ++V+ RLS V+ D + V + G I E G +LI+
Sbjct: 566 TSALDTESESVVQAALDKAREGRTTVVVAHRLSTVRNADLIAVFESGVITEQGNHSQLIE 625
Query: 563 KGGIFSEMM 571
K GI+ +++
Sbjct: 626 KKGIYYKLV 634
Score = 236 bits (596), Expect = 5e-61
Identities = 173/587 (29%), Positives = 295/587 (49%), Gaps = 38/587 (6%)
Query: 9 IRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR-----YG 63
++L+ + +F+ G F I+ V+ I G+ + + +R Y
Sbjct: 707 LKLMKLNKNEWPYFVAGTFCAIVNGALQPAFSVIFSEII--GIFSETDQKVLREKSNLYS 764
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
LL L +G+++ + KA + LR AF+A+ R +M +FD K +G L +
Sbjct: 765 LLFLALGIISFFTFFVQGFAFGKAGEILTMKLRFMAFKAMLRQDMAWFDDPKNSTGALTT 824
Query: 122 RITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVGLN 177
R+ ND ++ R+ ++ +I IIISL Y +TL ++A++ I V G+
Sbjct: 825 RLANDASQVKGATGVRLALIAQNIANLGTGIIISLVY--GWQLTLLLLAVVPIIAVAGMI 882
Query: 178 TTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
+ DKI + IAT I I+T+ SL+ E+ + + + Y +V
Sbjct: 883 EMKMLAGHAKKDKIELEAA--GKIATEAIENIRTVASLTREKRFELMYGEHLLVPYRNSV 940
Query: 238 KAMKITALYGNAPFLVLGLAMSTMFY-YGGKAIIQNTLTVGELVAFLTYMLT---MMWPL 293
K I L+ + MF+ Y G L V + + T L +++
Sbjct: 941 KKAHIFGF-------CFSLSQAMMFFTYAGCFRFGAYLVVNGHIEYKTVFLVFSAVVFGA 993
Query: 294 RALGFTIG---DIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTY 348
ALG T D ++ +A+ LF + + P ID D + G +DV Y
Sbjct: 994 MALGQTSSFAPDYAKAKISAAHLFVLFNRVPP-IDSYREDGEKPEKFGGNTRIKDVKFNY 1052
Query: 349 HTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
V L+G++ V+ GE + + G G GKS++++L+ RFY P GE++ D ++ +
Sbjct: 1053 PNRPEVKILQGLNLAVEKGETLALVGSSGCGKSTVVQLLERFYDPLSGEIVFDDIDAKTL 1112
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKG 464
+ LR + V QEP +F+ +I ENIA + + EE+ AAK A IH FI SLP+
Sbjct: 1113 NIQWLRSHIGIVSQEPILFDFTIAENIAYGDNSREVSHEEIISAAKAASIHSFIDSLPEK 1172
Query: 465 YDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQD 524
Y+T VG+KG LSGGQ+QRIA+ARA++ P+I+LLD+ S LD E+EK + E L + +
Sbjct: 1173 YNTRVGDKGTQLSGGQKQRIAIARALIRKPQILLLDEATSALDTESEKIVQEALDKAREG 1232
Query: 525 KTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
+T ++++ RLS ++ D++ V+++GK++E G ++L+ + G + ++
Sbjct: 1233 RTCIVIAHRLSTIQNADKIAVIQNGKVIEQGTHQQLLAEKGFYYSLV 1279
>dbj|BAA96612.1| (AP002482) Similar to Arabidopsis thaliana chromosome 2, BAC F14M4
; putative ABC transporter (AC004411) [Oryza sativa]
Length = 1285
Score = 253 bits (640), Expect = 3e-66
Identities = 176/551 (31%), Positives = 290/551 (51%), Gaps = 29/551 (5%)
Query: 41 VLIRNAIDK-GVSTGAYKVAIRYGLLIL---LVGVLNGVFSLAGRYLLVKAAQYAVYYLR 96
VL N ID G + G + V R ++ L + + + V S + + +R
Sbjct: 90 VLFGNLIDAFGGAMGIHDVVNRVSMVSLEFIYLAIASAVASFVQVTCWMITGERQAARIR 149
Query: 97 MDAFRAIQRHEMEFFDK-TFSGQLISRITNDT--------ERITRFLSFRVRMLLYSIFL 147
+ I R E+ FFDK T +G+++ R++ DT E++ +F+ V L F+
Sbjct: 150 NLYLKTILRQEIAFFDKYTNTGEVVGRMSGDTVLIQDAMGEKVGKFIQLVVTFL--GGFI 207
Query: 148 IIISLYYMVRMNITLTMVALITIAIVVG-LNTTYAMKVRPIYDKIRHQTGVIASIATGTI 206
+ + ++ +TL M+A I +V G + + K+ + ++ V+ TI
Sbjct: 208 VAFAQGWL----LTLVMMATIPPLVVAGAVMSNVVAKMASLGQAAYAESSVVVE---QTI 260
Query: 207 AGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGG 266
I+T+ S + E+ K+++ + Y V+ L ++L S +YG
Sbjct: 261 GSIRTVASFTGEKQAVEKYNKSLKSAYKSGVREGLAAGLGMGTVMVLLFCGYSLGIWYGA 320
Query: 267 KAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP 326
K I+ T +++ + +LT L ++ AAA ++F+ I+ P+ ID
Sbjct: 321 KLILLKGYTGAKVMNVIFAVLTGSLALGQASPSMKAFAGGQAAAYKMFETINRKPE-IDA 379
Query: 327 --PDAVEISNPRGEIEFRDVWLTYHT--GRTVLKGVSFKVKPGEKVLITGPPGSGKSSIL 382
++ + RG+IEFRDV+ +Y T + +G S + G V + G GSGKS+++
Sbjct: 380 YSTTGMKPDDIRGDIEFRDVYFSYPTRPDEQIFRGFSLSIPSGTTVALVGQSGSGKSTVI 439
Query: 383 KLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQ 442
LI RFY P G+VLIDGVN+ + + +R + V QEP +F SI+ENIA K NAT
Sbjct: 440 SLIERFYDPQLGDVLIDGVNLKEFQLRWIRSKIGLVSQEPVLFAASIKENIAYGKDNATD 499
Query: 443 EEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
+E+ AA++A FI +P+G DT VGE G LSGGQ+QRIA+ARA+L +P+I+LLD+
Sbjct: 500 QEIRAAAELANASKFIDKMPQGLDTSVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEA 559
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK 562
S LDAE+E+ + E L ++ ++T +IV+ RLS V+ D + V+ G +VE G EL+K
Sbjct: 560 TSALDAESERIVQEALDRVMTNRTTVIVAHRLSTVRNADTIAVIHQGTLVEKGPHHELLK 619
Query: 563 -KGGIFSEMMK 572
G +S+++K
Sbjct: 620 DPEGAYSQLIK 630
Score = 239 bits (603), Expect = 7e-62
Identities = 157/515 (30%), Positives = 279/515 (53%), Gaps = 21/515 (4%)
Query: 67 LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRIT 124
L + V + +FS+AG L+ + +R+ F + E+E+FD + SG + +R++
Sbjct: 774 LSLPVSSYLFSIAGCRLIKR--------IRLMTFEKVVNMEIEWFDHPENSSGAIGARLS 825
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK- 183
D ++ + +++++ + +I L N L+++ L I ++ GLN MK
Sbjct: 826 ADAAKVRGLVGDALQLVVQNTTTLIAGLVIAFVSNWELSLIILALIPLI-GLNGWIQMKF 884
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
++ + + +A ++ I+T+ S S EE V + ++ E ++ I+
Sbjct: 885 IQGFSADAKMMYEEASQVANDAVSSIRTVVSFSAEEKVMDLYKKKCEGPLRTGIRTGIIS 944
Query: 244 ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELV-AFLTYMLTMMWPLRALGFTIGD 302
+ F +L + FY G + + +N T ++ FL + + ++ T D
Sbjct: 945 GIGFGVSFFLLFGVYAASFYAGARLVEENKTTFPKVFRVFLALAMAAIGVSQSSTLT-SD 1003
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRGEIEFRDVWLTYHTGRTV--LKGV 358
++ +A S +F ++D + IDP + V + G IEF+ V Y T V + +
Sbjct: 1004 SSKAKSAVSSIFAIVDRKSR-IDPSEDAGVTVETLHGNIEFQHVSFRYPTRPDVEIFRDL 1062
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
+ G+ V + G GSGKS+ + L+ RFY P G +L+DGV++ K + + LR+ + V
Sbjct: 1063 CLTIHSGKTVALVGESGSGKSTAISLLQRFYDPDVGHILLDGVDIQKFQLKWLRQQMGLV 1122
Query: 419 PQEPFIFNRSIRENIALAKPN-ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLS 477
QEP +FN ++R NIA K AT+ E+ AAK+A H FI+S +GY T VGE+G LS
Sbjct: 1123 SQEPALFNDTVRANIAYGKEGEATESEIIEAAKLANAHKFISSSHQGYGTTVGERGAQLS 1182
Query: 478 GGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLV 537
GGQ+QRIA+ARA++ +PKI+LLD+ S LDAE+E+ + + L ++ ++T +IV+ RLS +
Sbjct: 1183 GGQKQRIAIARAIVKDPKILLLDEATSALDAESERVVQDALDRVMVNRTTVIVAHRLSTI 1242
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMM 571
+ D + V+K+G I+E GK + L+ K G ++ ++
Sbjct: 1243 QNADLIAVVKNGVIIEKGKHDTLMNIKDGAYASLV 1277
>pir||B71676 probable ABC transporter msbA2 - Rickettsia prowazekii
>gi|3861232|emb|CAA15132.1| (AJ235272) PROBABLE
TRANSPORT ATP-BINDING PROTEIN MSBA (msbA2) [Rickettsia
prowazekii]
Length = 576
Score = 253 bits (639), Expect = 4e-66
Identities = 162/575 (28%), Positives = 300/575 (52%), Gaps = 13/575 (2%)
Query: 5 INQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGL 64
I L RL YLR + +I + ++ +S + ++ + R+ ID+G++ + L
Sbjct: 3 IKLLYRLAKYLRFYKKDLIIVMISLLSVSASLLLIGSIFRDLIDRGLAEDNILSVNKSIL 62
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
I L+ V+ V S Y + A+ V +R +A+ + +E+E +++ G +ISR+T
Sbjct: 63 YICLLIVILSVASFFRSYFINNVAEKIVNQIRKEAYSNLINYEIEEYEELKIGDIISRLT 122
Query: 125 NDTERIT----RFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
ND ++I FLSF +R + ++I S+ M + L + +ITI I++ +
Sbjct: 123 NDIDQIATLIVNFLSFFIR----NSVMLIGSITLMFFESFKLASIVIITIPILLVPLIKF 178
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
V+ + K ++ S T I+ I + + + N F + + +
Sbjct: 179 GKHVKALSKKALESKSLLVSDIDETFNNIRVIYAFNHQINKIADFDTKLQSYLIYCKTRL 238
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
KI AL+ V+ L ++ + + G I+Q L+ G++++F+ Y + + +
Sbjct: 239 KIRALFFAISIAVIFLTITLIVWIGASDIVQGDLSAGQIISFIYYAIIAGVSSGGIFELL 298
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRG-EIEFRDVWLTYHT--GRTVLKG 357
++ A R+ +ID SI + ++N IEF++V TY++ V+
Sbjct: 299 SEMHLPTTALERIITIIDKT--SIVHNNYYALNNSDAISIEFKNVDFTYNSRPNLKVINN 356
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
+S K+ + V I G G+GKS++++L+ RFY+ G +LI+ +++ +K ++RK +AY
Sbjct: 357 MSLKINSNKFVGIVGRSGAGKSTLIQLLLRFYRQENGTILINNQDISFVKPTDIRKFIAY 416
Query: 418 VPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLS 477
VPQE IF+ +I+ NI A+ E+ KI I +F L G +T +GEKG+ LS
Sbjct: 417 VPQEASIFSDTIKSNIIFGNNKASDYEINEIIKITGIEEFSTKLHDGINTKIGEKGVRLS 476
Query: 478 GGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLV 537
GGQ+QRIA+ARA+L PKI+LLD+ +S LD +E+KL+ +K+I++ + ++ R+S +
Sbjct: 477 GGQKQRIAIARALLRKPKILLLDEAMSALDTMSEQKLLNAIKKIMKGNIIISIAHRISSI 536
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
+ D ++V+ G +V +G +L K I+ + +
Sbjct: 537 ESADYILVIDKGGVVTEGSHYDLSKNSEIYRNICR 571
>pir||T17482 ABC-type transport protein homolog - Amycolatopsis orientalis
>gi|2894187|emb|CAA11793.1| (AJ223999) PCZA363.2
[Amycolatopsis orientalis] >gi|5051822|emb|CAB45051.1|
(AL078635) putative ABC transporter [Amycolatopsis
orientalis]
Length = 650
Score = 252 bits (638), Expect = 6e-66
Identities = 173/596 (29%), Positives = 308/596 (51%), Gaps = 43/596 (7%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
L R+L Y R H + + +L S P+L++ ID G+ + I L
Sbjct: 29 LRRVLGYFRPHVGKVALFGLVAVLESLIVVATPLLLKELIDNGIEKNDLGLVIWMAALTA 88
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
++ VL +L Y+ K + Y LR+ A ++R + FF +T +G L+ R+ T
Sbjct: 89 VLAVLAAGLTLVSGYISGKIGEGITYDLRVQALDHVRRLPIAFFTRTQTGVLVGRL--HT 146
Query: 128 ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
E I F LL + ++++L ++ + +VA+I++A++ + R I
Sbjct: 147 ELIMAQQHFTG--LLMATTSLVMALVVLIELFYLSWLVAVISLALIPLFLVPWVRVGRVI 204
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTK-FSQENEELYSLNVKAMKIT--- 243
+ +G TG + G+ + +V+ + +K F + NEE+ +A I
Sbjct: 205 ----QRLSGRQMDANTG-LGGLLQ-ERFNVQGAMLSKLFGRPNEEMAEFEDRASGIRKIG 258
Query: 244 ---ALYGNAPFLVLGL----AMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRAL 296
+++G F+++ L A + ++ GG ++ VG LVA T + + P+ L
Sbjct: 259 VSLSVWGRMAFVMMALMASLATALVYGVGGGLVLAGAFQVGTLVAIATLLGRLFGPITQL 318
Query: 297 GFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRG-EIEFRDVWLTYHTGRTV- 354
Q + + SR+F+++D P + PDAV++ +IEF +V Y T V
Sbjct: 319 SGMQELFQTVVVSFSRVFELLDLKPLIQERPDAVKLDKDVAPDIEFENVSFRYPTADEVS 378
Query: 355 --------------------LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKG 394
L+ VSF V+ G + GP G+GKS+I L++R Y P G
Sbjct: 379 LASLEHLKAKRERGEVTPDVLRDVSFHVQAGTLTALVGPSGAGKSTITHLVSRLYDPNSG 438
Query: 395 EVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKI 454
V + G ++ + +++R+ V V Q+ ++F+ +IREN+ A+P AT++E+ A K A+I
Sbjct: 439 TVRVGGHDLRDLTFDSIREAVGVVSQDAYLFHDTIRENLLYARPTATEDELIEACKGAQI 498
Query: 455 HDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKL 514
D I SLP G DTV G++G +SGG++QR+A+AR +L P+IV+LD+ ++LD+E+E +
Sbjct: 499 WDLIESLPLGLDTVTGDRGYRMSGGEKQRLAIARLLLKEPRIVVLDEATAHLDSESEAAV 558
Query: 515 VEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
LK L+ +T+L+++ RLS ++ D+++V+ G + E G +EL+ KGG+++E+
Sbjct: 559 QRALKTALRSRTSLVIAHRLSTIREADQILVIDGGGVRERGTHDELMAKGGLYAEL 614
>sp|P55469|Y4GM_RHISN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEIN Y4GM
>gi|2182416|gb|AAB91687.1| (AE000075) Y4gM [Rhizobium
sp. NGR234]
Length = 586
Score = 252 bits (636), Expect = 1e-65
Identities = 151/565 (26%), Positives = 288/565 (50%), Gaps = 3/565 (0%)
Query: 8 LIRLLSYLRGH-AVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLI 66
L+RLL+ H A + I + +++++ S ++R+ ++ V + + + +
Sbjct: 14 LMRLLAENFKHQAPWYGIAIGSMVVVAVMTSASAWIMRDVVNSTVVSKDIEKVFGVAVTV 73
Query: 67 LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITND 126
++ + G+ + L KA + + + F + R + F+ S +L+ R+TN+
Sbjct: 74 AIIFAVKGLATYVQSIFLSKAGNNIIAHTQRRLFEHVLRQGLSFYSIYPSSELLVRLTNN 133
Query: 127 TERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMV-ALITIAIVVGLNTTYAMKVR 185
+ + + V + +F ++ L MV L++V A + ++G+ KVR
Sbjct: 134 AQAVRSVIELVVTSFIRDLFSLMGLLAVMVIQQPLLSLVSAAVGPGAILGVRVL-TRKVR 192
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
I + G I T GI+ +K+ ++E+ ++ + + ++ ++ A
Sbjct: 193 KIMELEIASIGQIIQSVQETSTGIRIVKAFALEDFMRRRMDKYIGDVERRANSIARLEAA 252
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+ G A++ + G ++Q T GEL++F+T +L P + L ++
Sbjct: 253 SSPIMETLSGFAIAGVIALSGVLVLQQGNTPGELMSFITALLLAYEPAKRLARMRISLES 312
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPG 365
+L ++ + D + + A+ + GEI F+DV +Y G + + ++ G
Sbjct: 313 ALVGVRMMYQLADHPIELTEKNSAIPLPEGPGEIRFKDVNFSYKNGERLFQNLNVTFPAG 372
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
+ + GP G+GKSSI+ LI R Y P G V +DG ++ + +LR + +V Q+ F+F
Sbjct: 373 KTTALVGPSGAGKSSIINLIMRLYDPDVGSVTVDGHDLKDVTFRSLRDRIGFVGQDTFLF 432
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
+ +I+ NI+L + A+ EE+ AAK A HDFI +P GYDT VGE GI LSGGQ+QRI
Sbjct: 433 SGTIKYNISLGREGASDEEIIEAAKTANAHDFIMKMPHGYDTEVGENGIKLSGGQKQRIT 492
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+ARAML N +I++ D+ S LD+E+E ++ + L + + +T ++++ RLS V D ++V
Sbjct: 493 IARAMLRNAEILIFDEATSALDSESEIQIRQALARLTRKRTTIMIAHRLSTVTAADNIVV 552
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEM 570
M+ G++ E G L+ + G++ +
Sbjct: 553 MEGGQVAEQGPQGRLLSQDGVYRRL 577
>dbj|BAA34383.1| (AB019513) ABC transporter [Streptomyces coelicolor A3(2)]
Length = 584
Score = 252 bits (636), Expect = 1e-65
Identities = 162/567 (28%), Positives = 275/567 (47%), Gaps = 15/567 (2%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVG 70
LLSY+R H G L ++ T ++P++ R ID A G L+ + G
Sbjct: 16 LLSYVRPHRTALFAGALLSLVTGATGLLLPLVARELIDDLAQDRAIT-----GALLAMSG 70
Query: 71 --VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTE 128
V N G Y+L + A+ V R + R + D+T G L++RIT+DT
Sbjct: 71 LVVANTALGALGSYVLRRTAESVVLGARRTLSSYLLRLRIAAVDRTEPGDLMARITSDTT 130
Query: 129 RITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
+ + + L ++ +L V M + ++ +T+A+V+G T + V I
Sbjct: 131 LLREVTTDSLIGLGTGGLTLVATL---VMMGVVDPVLLGVTLAVVLGAGTVLGLIVPRIN 187
Query: 189 DKIRHQ---TGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
R GV+ + + ++T+K+ E + + EE + +V+A K +A
Sbjct: 188 RASRQAQDAVGVMGAALERILGALRTVKASGAEPREERVLHEAAEESWRQSVRAAKWSAA 247
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
GN L + +A T+ GG + + VG LVAFL ++ +M P++ + I Q
Sbjct: 248 AGNTAGLAMQIAFITVLAVGGARVATGAIDVGTLVAFLLFVFYLMSPIQQVVGAITQYQT 307
Query: 306 SLAAASRLFDVID-SAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLK-GVSFKVK 363
AA R+ D + A P P + FR+V Y + GVSF+V
Sbjct: 308 GRAALGRIQDALGLPAEPQARPVPLPSAGAPPASVSFREVRFRYADDLPYIHHGVSFEVP 367
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
GP G+GK+++ L+ RFY P GE+ +DG ++ + +LR + YV Q+
Sbjct: 368 ARGMTAFVGPSGAGKTTVFSLVERFYDPDSGEITLDGRSLGDWELSSLRASIGYVEQDAP 427
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+ + S+R+N+ L P + + K ++ + LP G +T+VG +G LSGG+RQR
Sbjct: 428 VLSGSLRDNLLLGNPEGDEATLAAVLKTTRLDGLVERLPNGLETLVGHRGTKLSGGERQR 487
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
+A+ARA+L P+++LLD+ S LDA E L + + ++ + T L+V+ RLS V + DR+
Sbjct: 488 VAIARALLRRPRLLLLDEATSQLDAVNEAALRDTVADVARTTTVLVVAHRLSTVTMADRI 547
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEM 570
+VM G++ G EL+ +++E+
Sbjct: 548 VVMDAGRVRAVGTHRELVTADPLYAEL 574
>emb|CAC14944.1| (AL449216) putative ABC transporter ATP-binding protein (fragment)
[Streptomyces coelicolor]
Length = 578
Score = 252 bits (636), Expect = 1e-65
Identities = 162/567 (28%), Positives = 275/567 (47%), Gaps = 15/567 (2%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVG 70
LLSY+R H G L ++ T ++P++ R ID A G L+ + G
Sbjct: 16 LLSYVRPHRTALFAGALLSLVTGATGLLLPLVARELIDDLAQDRAIT-----GALLAMSG 70
Query: 71 --VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTE 128
V N G Y+L + A+ V R + R + D+T G L++RIT+DT
Sbjct: 71 LVVANTALGALGSYVLRRTAESVVLGARRTLSSYLLRLRIAAVDRTEPGDLMARITSDTT 130
Query: 129 RITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
+ + + L ++ +L V M + ++ +T+A+V+G T + V I
Sbjct: 131 LLREVTTDSLIGLGTGGLTLVATL---VMMGVVDPVLLGVTLAVVLGAGTVLGLIVPRIN 187
Query: 189 DKIRHQ---TGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
R GV+ + + ++T+K+ E + + EE + +V+A K +A
Sbjct: 188 RASRQAQDAVGVMGAALERILGALRTVKASGAEPREERVLHEAAEESWRQSVRAAKWSAA 247
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
GN L + +A T+ GG + + VG LVAFL ++ +M P++ + I Q
Sbjct: 248 AGNTAGLAMQIAFITVLAVGGARVATGAIDVGTLVAFLLFVFYLMSPIQQVVGAITQYQT 307
Query: 306 SLAAASRLFDVID-SAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLK-GVSFKVK 363
AA R+ D + A P P + FR+V Y + GVSF+V
Sbjct: 308 GRAALGRIQDALGLPAEPQARPVPLPSAGAPPASVSFREVRFRYADDLPYIHHGVSFEVP 367
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
GP G+GK+++ L+ RFY P GE+ +DG ++ + +LR + YV Q+
Sbjct: 368 ARGMTAFVGPSGAGKTTVFSLVERFYDPDSGEITLDGRSLGDWELSSLRASIGYVEQDAP 427
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+ + S+R+N+ L P + + K ++ + LP G +T+VG +G LSGG+RQR
Sbjct: 428 VLSGSLRDNLLLGNPEGDEATLAAVLKTTRLDGLVERLPNGLETLVGHRGTKLSGGERQR 487
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
+A+ARA+L P+++LLD+ S LDA E L + + ++ + T L+V+ RLS V + DR+
Sbjct: 488 VAIARALLRRPRLLLLDEATSQLDAVNEAALRDTVADVARTTTVLVVAHRLSTVTMADRI 547
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEM 570
+VM G++ G EL+ +++E+
Sbjct: 548 VVMDAGRVRAVGTHRELVTADPLYAEL 574
>pir||JE0248 ATP-binding cassette half-transporter - rat
>gi|2982567|emb|CAA05793.1| (AJ003004) ABC transporter
[Rattus norvegicus]
Length = 836
Score = 251 bits (635), Expect = 1e-65
Identities = 164/582 (28%), Positives = 289/582 (49%), Gaps = 14/582 (2%)
Query: 3 KSINQLIRLLS-YL--RGHAVHFLIGLFLIILMSYT---NSIVPVLIRNAIDKGVSTGAY 56
+ + + +RLLS YL RG L L + LM N +VP+ R+ ++ S +
Sbjct: 240 RDLGRKLRLLSGYLWPRGSPSLQLTVLLCMGLMGLDRALNVLVPIFYRDIVNLLTSKAPW 299
Query: 57 K----VAIRYGLLILLVGV---LNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEME 109
Y L L G G S +L ++ Q+ + + F + +
Sbjct: 300 SSLAWTVTTYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRGVELRLFSHLHELSLR 359
Query: 110 FFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISL-YYMVRMNITLTMVALI 168
+ +G+++ + T +T LS+ V ++ ++ III + Y+ + N ++ +
Sbjct: 360 WHLGRRTGEVLRIVDRGTSSVTGLLSYLVFNIIPTLADIIIGIIYFSMFFNAWFGLIVFL 419
Query: 169 TIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQE 228
+++ + L + Q + A ++ +T+K + E ++ +
Sbjct: 420 CMSLYLILTIMVTEWRAKFRRDMNTQENATRARAVDSLLNFETVKYYNAEGYELERYREA 479
Query: 229 NEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLT 288
+ L K+ L +V+G + + + L VG+ V F TY+
Sbjct: 480 ILKFQGLEWKSTASLVLLNQTQNMVIGFGLLAGSLLCAYFVSERRLQVGDFVLFGTYITQ 539
Query: 289 MMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY 348
+ PL G IQ + +FD++ + D P A + +G +EF +V +Y
Sbjct: 540 LYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDVPGAGPLRFHKGRVEFENVHFSY 599
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
GR L+ VSF V PG+ V + GP G+GKS+IL+L+ RFY + G + IDG +++++
Sbjct: 600 ADGRETLQDVSFTVMPGQTVALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQ 659
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTV 468
+LR + VPQ+ +FN +I NI + A E++ AA+ A IHD I S P+GY+T
Sbjct: 660 ISLRSHIGVVPQDTVLFNDTIANNIRYGRVTAGDSEIQAAAQAAGIHDAILSFPEGYETQ 719
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
VGE+G+ LSGG++QR+A+AR +L P I+LLD+ S LD E+ + L ++ ++T +
Sbjct: 720 VGERGLKLSGGEKQRVAIARTILKAPDIILLDEATSALDTSNERAIQASLAKVCTNRTTI 779
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+V+ RLS V D+++V+KDG I+E G+ E L+ +GG+++EM
Sbjct: 780 VVAHRLSTVVNADQILVIKDGCIIERGRHEALLSRGGVYAEM 821
>gb|AAD15830.1| (AF062387) TAP2 protein [Xenopus laevis]
Length = 720
Score = 251 bits (635), Expect = 1e-65
Identities = 159/565 (28%), Positives = 292/565 (51%), Gaps = 6/565 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSI-VPVLIRNAIDKGVSTGAYKVAI 60
+K IRLL Y + + L G F + ++ + VP ID + V +
Sbjct: 134 KKERVNFIRLLKYSKPDWLQ-LSGAFSCLTLALIGELFVPYYTGRVIDILSTKYNESVFM 192
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
L + + + + F+ + L + + LR+ FR++ + ++ FF+ T +G +
Sbjct: 193 EAILFMAIFSITSSFFAGSRGGLFMFSHSSLTQRLRLLLFRSLIKQDIAFFELTKTGDIT 252
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
SR++ DT R++R ++ V ++L ++ I +M ++ LT++ I+ Y
Sbjct: 253 SRLSQDTARVSRAIAANVNIILRTLVKCIGVYSFMFSLSWQLTLLTFISAPFTWITQKVY 312
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
+ + K++ + +A ++T+ S + EE ++ + E Y+L
Sbjct: 313 NNYHQKLVQKVQDSIASSSELAREMFESVRTVYSFAAEEEEAKRYEKSLRETYNLQTCRD 372
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
+ ALY L+ + Y G + I +++G++V+F+ Y + +R L +
Sbjct: 373 FVRALYLLVIKLINLSTQVALLYCGQQLIHSGNISIGKMVSFILYQMESGDYIRTLVHML 432
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGV 358
++ S A ++F +D P+ + + N RG+ EF++V +Y + L+ V
Sbjct: 433 SEVTHSAGAGHKVFHYLDQVPE-VSNTGKLCPDNLRGQFEFKNVTFSYPSRPDAPSLQNV 491
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
SFK+ PG + GP G GK++ + L+ RFY+P G +L+DG+ + + K + L VA V
Sbjct: 492 SFKLPPGSVTALVGPSGGGKTTCVSLLERFYEPQIGAILLDGIPLGEYKHQYLHSKVALV 551
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
QEP +F +IRENI + ++++++ AA+ AK FI+ + K YDT V + G LS
Sbjct: 552 AQEPVLFAGTIRENIGYGLKDISEKQLKEAARKAKADTFISEMEKLYDTDVLDSGAQLSA 611
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
GQ+QR+ALARA+ PK+++LD+ S LDAETE ++ + L + L D + LI++ RL ++
Sbjct: 612 GQKQRVALARALARKPKLLILDEASSCLDAETEHEIQQSL-QTLPDVSLLIIAHRLRTIQ 670
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKK 563
D ++V++ G +VE G EEL++K
Sbjct: 671 KADNILVLEGGYLVEQGTHEELVEK 695
>gi|6755046 ATP-binding cassette, sub-family B, member 1; P glycoprotein 1 [Mus
musculus] >gi|126927|sp|P06795|MDR1_MOUSE MULTIDRUG
RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1)
>gi|72474|pir||DVMS1 multidrug resistance protein 1 -
mouse >gi|387426|gb|AAA79005.1| (M14757) multidrug
resistance protein [Mus musculus]
Length = 1276
Score = 251 bits (634), Expect = 2e-65
Identities = 171/582 (29%), Positives = 301/582 (51%), Gaps = 37/582 (6%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVP----VLIRNAIDKGVSTGAYKVAIRYG 63
L+ LL + G+ IL S TN P ++ +++++ ++ AY
Sbjct: 63 LLPLLMLVFGNMTDSFTKAEASILPSITNQSGPNSTLIISNSSLEEEMAIYAY------- 115
Query: 64 LLILLVGVLNGVFSLAGRYLLVK----AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
G+ GV +A Y+ V AA ++ +R F AI E+ +FD G+L
Sbjct: 116 ---YYTGIGAGVLIVA--YIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGEL 170
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R+T+D +I + ++ M SI + LT+V ++ ++ ++GL++
Sbjct: 171 NTRLTDDVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLV-ILAVSPLIGLSSA 229
Query: 180 YAMKVRPIYDKIRHQTGVIA-SIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
KV + Q A ++A +A I+T+ + ++ ++++ EE ++ +K
Sbjct: 230 LWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKNVGIK 289
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
++ +L++ + + F+YG ++ N ++GE++ +L + + L
Sbjct: 290 KAITASISIGIAYLLVYASYALAFWYGTSLVLSNEYSIGEVLTVFFSILLGTFSIGHLAP 349
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDP-------PDAVEISNPRGEIEFRDVWLTYHTG 351
I + AA +F +ID+ P SID PD++ G +EF++V Y +
Sbjct: 350 NIEAFANARGAAFEIFKIIDNEP-SIDSFSTKGYKPDSI-----MGNLEFKNVHFNYPSR 403
Query: 352 RTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTE 409
V LKG++ KVK G+ V + G G GKS+ ++L+ R Y P +G V IDG ++ I
Sbjct: 404 SEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTINVR 463
Query: 410 NLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
LR+I+ V QEP +F +I ENI + + T +E+E+A K A +DFI LP +DT+V
Sbjct: 464 YLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLV 523
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
GE+G LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD E+E + L + + +T ++
Sbjct: 524 GERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIV 583
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ RLS V+ D + G IVE G +EL+++ GI+ +++
Sbjct: 584 IAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLV 625
Score = 243 bits (614), Expect = 4e-63
Identities = 156/528 (29%), Positives = 286/528 (53%), Gaps = 23/528 (4%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ L L++G+++ V + KA + +R F+++ R ++ +FD K +G L
Sbjct: 753 FSLFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSL 812
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ +D + + R+ ++ ++ +I+SL Y +TL +V +I + ++ G
Sbjct: 813 TTRLASDASSVKGAMGARLAVVTQNVANLGTGVILSLVY--GWQLTLLLVVIIPLIVLGG 870
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK Q + IAT I +TI SL+ E+ +T ++Q + Y
Sbjct: 871 IIEMKLLSGQALKDK--KQLEISGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRN 928
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+K + + + ++ + + F +G + Q +T ++ + +++ A
Sbjct: 929 AMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAQQLMTFENVMLVFS---AVVFGAMA 985
Query: 296 LGFTIG---DIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHT 350
G T D ++ +AS + +I+ P+ ID + ++ + G ++F V Y T
Sbjct: 986 AGNTSSFAPDYAKAKVSASHIIRIIEKTPE-IDSYSTEGLKPTLLEGNVKFNGVQFNYPT 1044
Query: 351 GRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
VL+G+S +VK G+ + + G G GKS++++L+ RFY P G V +DG + ++
Sbjct: 1045 RPNIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNV 1104
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYD 466
+ LR + V QEP +F+ SI ENIA + + EE+ RAAK A IH FI SLP Y+
Sbjct: 1105 QWLRAHLGIVSQEPILFDCSIAENIAYGDNSRAVSHEEIVRAAKEANIHQFIDSLPDKYN 1164
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T VG+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T
Sbjct: 1165 TRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRT 1224
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++++ RLS ++ D ++V+++GK+ E G ++L+ + GI+ M++AG
Sbjct: 1225 CIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMVQAG 1272
>pir||T21266 hypothetical protein F22E10.1 - Caenorhabditis elegans
>gi|3876291|emb|CAA91799.1| (Z67882) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=427.5,
E-value=3.8e-125, N=2; PF00664 (ABC transporter
transmembrane region.), Score=255.6, E-value=2.1e-73,
N=2~cDNA EST yk10e8.3 comes from this gene~cDNA EST
yk10e8.5 come>
Length = 1318
Score = 251 bits (634), Expect = 2e-65
Identities = 154/553 (27%), Positives = 295/553 (52%), Gaps = 19/553 (3%)
Query: 29 IILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAA 88
II + TNS+ LI NA A +G + ++V ++N V + +Y ++
Sbjct: 112 IIAGNITNSL---LIHNATSDDFYDSAMTNVWLFGGIGIIVLIVNFVQYMCFQYCCIRIT 168
Query: 89 QYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFL- 147
++ ++I R +FDK SG L +++ ++ ERI + ++ +L+ + +
Sbjct: 169 SK----MKQHYIQSILRQNAGWFDKNHSGTLTTKLHDNMERINEGIGDKLGVLIRGMVMF 224
Query: 148 ---IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATG 204
I+IS +Y R+ + + + + + + + + K G SIA
Sbjct: 225 VAGIVISFFYEWRLALMMMGIGPLCCVCM----SLMSRSMSSFTSKELAGVGKAGSIAEE 280
Query: 205 TIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYY 264
++ G++T+++ + +E + K++ E + S ++ ++G L L YY
Sbjct: 281 SLMGVRTVQAFNGQEEMVEKYTVELGKGKSFAIQKGLWGGVFGGIFLLFLFSYFGGGIYY 340
Query: 265 GGKAIIQNTL-TVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK- 322
GG+ + + T G++ + ML + L + + + + AA+ ++++ID P
Sbjct: 341 GGQLLRWKIIETPGDVFIVVISMLIGAYFLGLISPHLMVLLNARVAAATIYEIIDRTPDI 400
Query: 323 SIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSS 380
+ + +++N G++ F +V Y T + V L G++ VKPG V + G G GKS+
Sbjct: 401 DVYSTEGQKMTNVVGKVVFEEVHFRYPTRKKVKVLNGLNLTVKPGTSVALVGHSGCGKST 460
Query: 381 ILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNA 440
+ L+ R Y+P G+V+IDG +V + + LRK V V QEP +FN +I N+ + P+A
Sbjct: 461 SVGLLTRLYEPEGGKVMIDGQDVRSLNIDWLRKTVGIVQQEPILFNDTIHNNLLIGNPSA 520
Query: 441 TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLD 500
T+E++ R K+A HDFI +P GY+T++G+ + LSGGQ+QR+A+AR ++ +PK++LLD
Sbjct: 521 TREDMIRVCKMANAHDFIQKMPNGYETMIGDGSVQLSGGQKQRVAIARTLIRDPKVLLLD 580
Query: 501 DPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEEL 560
+ S LDA++E + L + +T ++++ RLS ++ D+++ ++G IVE G EEL
Sbjct: 581 EATSALDAQSESVVQSALNNAAKGRTTIMIAHRLSTIREADKIVFFENGVIVESGNHEEL 640
Query: 561 IKKGGIFSEMMKA 573
+ GG ++++++A
Sbjct: 641 VALGGRYAKLVEA 653
Score = 194 bits (488), Expect = 2e-48
Identities = 146/532 (27%), Positives = 262/532 (48%), Gaps = 43/532 (8%)
Query: 60 IRYGLLILLVGVLNG-VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS-- 116
+ GL + + V++G +F++ L +K R+ +F+ + + FFD
Sbjct: 805 VALGLFVFITQVISGTLFTIVAENLGLK--------FRVQSFKNLLYQDASFFDNPAHAP 856
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLY--YMVRMNITLTMVALITIAIVV 174
G+LI+R+ +D + + R+ ++YSI I I+L Y+ I + +I + +
Sbjct: 857 GKLITRLASDAPNVKAVVDTRMLQVIYSITSITINLITGYIFCWRIAIAGTIMIVLFATM 916
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEEN----------VQTK 224
++ Y + + + + G IA I +KTI+ L+ + VQ K
Sbjct: 917 MISMAYKIARENLKQIRKDEAG---KIAIEIIESVKTIQLLTSTQRFLTHYKDAQLVQHK 973
Query: 225 FSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLT 284
+ S+N A+ T +Y A F+ G+ M++ I++ T + +
Sbjct: 974 SEMRKSYIQSVN-NAISQTFMYF-AMFVCYGVGTPLMYH----GIVEAEPTFRAINCMMM 1027
Query: 285 YMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP--RGEIEFR 342
+ +M + ++ AA LF +I K+ D +E +N RG + F
Sbjct: 1028 GSVAVMHS----SHNFPEFVKAKTAAGMLFKLIYRKSKT---GDVMEGNNTEIRGNVLFE 1080
Query: 343 DVWLTY--HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDG 400
V +Y + V+ + F G+ V + GP G+GKS+ + ++ RFY + G + IDG
Sbjct: 1081 SVKFSYPQRPMQPVMTDLHFSAHSGQTVALVGPSGTGKSTCIAMLERFYDVSGGALRIDG 1140
Query: 401 VNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIAS 460
N+ + +LR +A V QEP +F +I+EN+ + + E+V +A ++A F+A+
Sbjct: 1141 QNIKSLSLHHLRTQMALVGQEPRLFAGTIKENVCFGLKDVSVEKVHQALELANASRFLAN 1200
Query: 461 LPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKE 520
LP G DT VGEKG LSGGQ+QRIA+ARA++ +PKI+LLD+ S LD+E+E+ + E L
Sbjct: 1201 LPAGIDTEVGEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEALDR 1260
Query: 521 ILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
+ +T + ++ RLS ++ D ++ + G + E G L+ G + ++K
Sbjct: 1261 AREGRTCITIAHRLSSIQNSDLIVYIDHGMVQEAGNHAHLMSLRGKYYNLIK 1312
>sp|P47261|Y015_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG015
>gi|1361881|pir||F64201 transport ATP-binding protein
msbA homolog MG015 - Mycoplasma genitalium
>gi|1045684|gb|AAC71231.1| (U39680) ABC transporter,
ATP-binding protein [Mycoplasma genitalium]
Length = 589
Score = 250 bits (633), Expect = 2e-65
Identities = 143/513 (27%), Positives = 276/513 (52%), Gaps = 22/513 (4%)
Query: 75 VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFL 134
VF++A Y+ +K Q LR A+ +Q FFD +G L+SR+TND I
Sbjct: 82 VFNVAQNYVGIKLYQQTCATLRWKAYLKMQSMSTSFFDTQNNGDLMSRLTNDMYNIDNLF 141
Query: 135 SFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQ 194
+ + S+F I+ + + ++ + +++L +A ++ + + K + Y ++++
Sbjct: 142 TQAGGQAIQSLFNILTTSVLIFLLSPVIALISLSILATLITFSFAFLKKSKTSYSQVQNN 201
Query: 195 TGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT-------ALYG 247
G ++ + K + L ++E + F Q N+ + V+ +
Sbjct: 202 LGDMSGYIEEVLTNHKVVHVLKLQEIMIKDFDQYNKSMIKPTVRGNTYSIFLFSWFGFIS 261
Query: 248 NAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI---- 303
N +LV ++++T F + + + G V ++ML+ + LR + + I
Sbjct: 262 NITYLV-SISIATAFS------VNSIPSFGISVINYSFMLSYIASLRQITLALDQIFTLW 314
Query: 304 ---QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSF 360
Q + +A R+F V+D + D ++ + +G I F +V Y+ + L G++F
Sbjct: 315 NLVQLGVVSAERVFKVLDLNVEK-DTATIDKLPDIKGNIRFENVAFGYNKDKPTLTGINF 373
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
VK G+ V I GP G+GKS+I+ L+ +FYKP +G++ +D ++ + + R+ ++ V Q
Sbjct: 374 SVKHGDVVAIVGPTGAGKSTIINLLMKFYKPFEGKIYMDNFEISDVTKKAWREKISIVLQ 433
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
+ F+F+ +I+ENI L + +AT +E+ A K A HDFI LPKGYDT + K LS G+
Sbjct: 434 DSFLFSGTIKENIRLGRQDATDDEIIAACKTANAHDFIMRLPKGYDTYISNKADYLSVGE 493
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
RQ + +ARA++ N ++LLD+ S++D +EK + E + ++++KT+ I+S RLS+++
Sbjct: 494 RQLLTIARAVIRNAPVLLLDEATSSVDVHSEKLIQESIGRLMKNKTSFIISHRLSIIRDA 553
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
++V+ DGK++E G ++L+K+ G ++ + ++
Sbjct: 554 TLIMVINDGKVLEMGNHDQLMKQNGFYARLKQS 586
>sp|O14286|YETI_SCHPO PUTATIVE ABC TRANSPORTER C8C9.18 IN CHROMOSOME I
>gi|11359219|pir||T39154 probable ABC transporter -
fission yeast (Schizosaccharomyces pombe)
Length = 693
Score = 250 bits (633), Expect = 2e-65
Identities = 155/561 (27%), Positives = 287/561 (50%), Gaps = 11/561 (1%)
Query: 20 VHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY---GLLILLVG---VLN 73
V + L L++ N VP ++ ID +T +V + G ++L G + +
Sbjct: 117 VRVVSALALLVAAKILNVQVPFYFKSIIDTMNTTLVQEVGALWSTVGAVVLGYGFARIFS 176
Query: 74 GVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRF 133
VF + +Q A+ + + ++ + +M F +G + + T+ I+
Sbjct: 177 TVFQELRNSVFAIVSQSAIRSVSSNVYQHLLNLDMNFHLSKQTGSITRAMDRGTKGISFI 236
Query: 134 LSFRVRMLL-YSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIR 192
LS V ++ ++ + ++S + + + +A T+A+ L T R ++ +
Sbjct: 237 LSSMVLHIIPITLEIAMVSGILTYKYGPSFSAIAATTVALYA-LFTVRTTSWRTVFRRQA 295
Query: 193 HQTGVIASIAT-GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPF 251
+ AS A ++ + +K+ + E +++ + NVK A +
Sbjct: 296 NAADSKASAAAIESLINYEAVKTFNNESYEMSRYEKHLSAYEKANVKVASSLAFLNSGQA 355
Query: 252 LVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAAS 311
++ A++ M Y G + I+ + LTVG+LV + + PL LG +++++
Sbjct: 356 IIFSTALTLMMYMGCRGIVTSNLTVGDLVMINQLVFQLSIPLNFLGSVYREMRQAFTDME 415
Query: 312 RLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLIT 371
+LF + + + PDA ++ G I+F +V +Y+ R +L G SF + G KV
Sbjct: 416 QLFSLKRINIQVKEAPDARDLVLKGGSIQFDNVHFSYNPNRPILNGCSFNIPAGAKVAFV 475
Query: 372 GPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRE 431
G G GKS+IL+L+ RFY G++LID + +I +LRK + VPQ+ +FN +I
Sbjct: 476 GASGCGKSTILRLLFRFYDTDSGKILIDNQRLDQITLNSLRKAIGVVPQDTPLFNDTILY 535
Query: 432 NIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAML 491
NI P A+ +E+ AAK AKIHD I S P+GY T VGE+G+ +SGG++QR+A++R +L
Sbjct: 536 NIGYGNPKASNDEIVEAAKKAKIHDIIESFPEGYQTKVGERGLMISGGEKQRLAVSRLLL 595
Query: 492 MNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVKLVDRVIVMKDG 549
NP+I+ D+ S LD TE+ L+ ++ ++++ KT++ ++ RL +K D + V++ G
Sbjct: 596 KNPEILFFDEATSALDTNTERALLRNINDLIKGSHKTSVFIAHRLRTIKDCDIIFVLEKG 655
Query: 550 KIVEDGKPEELIKKGGIFSEM 570
++VE G E+L+ K +++ M
Sbjct: 656 RVVEQGSHEQLMAKNSVYTSM 676
>gb|AAB09036.1| (U68242) TxpA [Bartonella bacilliformis]
Length = 641
Score = 250 bits (632), Expect = 3e-65
Identities = 161/573 (28%), Positives = 286/573 (49%), Gaps = 13/573 (2%)
Query: 9 IRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILL 68
+R+LSYL FL+ I ++ P+L + ID +A + L+ L
Sbjct: 54 VRVLSYLNQEKNAFLLICTANITLAIITIAEPILFGHVIDT--------IADKSDTLVTL 105
Query: 69 -VGVLNGVFSLAGRYLLVKAAQYAVYYLRMD----AFRAIQRHEMEFFDKTFSGQLISRI 123
V + G+ ++ L+ + A + R+ +F I + + + + + +
Sbjct: 106 AVWMCFGISNIIAYVLVARGADRLAHRCRLTVLEKSFARIISMPLIWHQQRGTSHALHTL 165
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
T+ ++ +R L + + + + +MN L++V ++ + + + K
Sbjct: 166 LRATDSMSSIWLEFMRQHLSTFVALFVLVPVTFKMNWRLSIVLMVLAILYILIARLVMQK 225
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
+ + H + T +I+ + ++S + + Q L S +
Sbjct: 226 TKNGQAAVEHYHHNLFKHITDSISNVSIVQSYNRITEETSALHQHTNNLLSAQTPVLNWW 285
Query: 244 ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
AL + +++ + G +I+ L+VGE+V F+ + M+ L + I
Sbjct: 286 ALASGLNRMASTISIVCVLLLGAFFVIKGQLSVGEVVTFVGFSQLMIGRLDQISGFINLA 345
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVK 363
S A FD+ DS ++ +P + + N +G I+F V + + +SF+VK
Sbjct: 346 VSSQAKLQEFFDMEDSTFQTNEPANLPSLPNVKGAIQFHHVTYEFPNSSQGVFDISFEVK 405
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
G+ V I GP G+GK++++ L+ R Y PT G + IDG+N+ I E+LRK +A V Q+
Sbjct: 406 AGQTVAIVGPTGAGKTTLINLLQRVYDPTVGYISIDGININSINRESLRKALATVFQDAG 465
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+F+R+IR+NI++ K AT EE+ A K A HDFI K YDT+VGE+G LSGG+RQR
Sbjct: 466 LFDRTIRDNISIGKTGATDEELYEATKTASAHDFILKKSKNYDTLVGERGSQLSGGERQR 525
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
+A+ARA+L N I++LD+ S LD ETE ++ + I Q++T I++ RLS ++ D V
Sbjct: 526 LAIARAILKNAPILILDEATSALDVETEIRVKNAIDCISQNRTTFIIAHRLSTIRNADLV 585
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
+ + G+++E G +ELI K G F +++K GG+
Sbjct: 586 LFLDQGRLIEKGSFQELINKDGHFYKLLKRGGL 618
>emb|CAB69751.1| (AL137187) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 577
Score = 250 bits (632), Expect = 3e-65
Identities = 149/566 (26%), Positives = 286/566 (50%), Gaps = 2/566 (0%)
Query: 8 LIRLL-SYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLI 66
LIRLL +YLR + + + L L + + +P L + ID+GV G + YG L+
Sbjct: 2 LIRLLRTYLRPYKKPIALLVALQFLQTCASLYLPTLNAHIIDEGVVKGDSGYILSYGALM 61
Query: 67 LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITND 126
+ + + V ++ + + A +R F +Q + LI+R TND
Sbjct: 62 IGISLAQVVCNIGAVFYGARTAAALGRDVRGAVFDRVQSFSAREVGHFGAPSLITRTTND 121
Query: 127 TERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRP 186
+++ +++ + + + + + +++ L+ V L + ++ T K+RP
Sbjct: 122 VQQVQMLALMTFTLMVSAPIMCVGGIVMALGLDVPLSGVLLGVVPVLAICVTLIVRKLRP 181
Query: 187 IYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALY 246
++ K++ + + + I G + I++ +E Q +F + N EL + + + AL
Sbjct: 182 LFRKMQVRLDTVNRVLREQITGNRVIRAFVRDEYEQQRFRKANTELTEVALGTGNLLALM 241
Query: 247 GNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRS 306
V+ L+ + ++G I + +G+L AFL Y++ ++ + F + R+
Sbjct: 242 FPVVMTVVNLSSIAVVWFGAHRIDSGGMQIGDLTAFLAYLMQIVMSVMMATFMFMMVPRA 301
Query: 307 LAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-VLKGVSFKVKPG 365
A R+ +V+++ + P V G +E R+ Y VL+ + +PG
Sbjct: 302 EVCAERIQEVLETESSVVPPVAPVTELRRHGHLEIREAGFRYPGAEEPVLRHIDLVARPG 361
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
E + G GSGKS++L L+ R + T GEVL++GV+V + + L K+V+ VPQ+P++F
Sbjct: 362 ETTAVIGSTGSGKSTLLGLVPRLFDATDGEVLVNGVDVRTVDPKTLAKVVSLVPQKPYLF 421
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
++ N+ P+AT EE+ A +A+ +F++ L G D + + G +SGGQRQR+A
Sbjct: 422 AGTVATNLRYGNPDATDEELWHALAVAQAKEFVSELEGGLDAPIAQGGTNVSGGQRQRLA 481
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+AR ++ P+I L DD S LD T+ L +L + + T +IV+QR++ ++ DR++V
Sbjct: 482 IARTLVQRPEIYLFDDSFSALDYATDAALRAELAQETAEATVVIVAQRVATIRDADRIVV 541
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEMM 571
+ +G++V G+ EL+ + E++
Sbjct: 542 LDEGRVVGVGRHHELMADNETYREIV 567
>gi|6755048 ATP-binding cassette, sub-family B, member 4; P glycoprotein 3;
multi-drug resistance 3 [Mus musculus]
>gi|387427|gb|AAA39514.1| (M33581) P-glycoprotein [Mus
musculus]
Length = 1276
Score = 249 bits (630), Expect = 5e-65
Identities = 152/494 (30%), Positives = 263/494 (52%), Gaps = 15/494 (3%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA ++ +R F AI E+ +FD G+L +R+T+D +I + ++ M ++
Sbjct: 135 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMA 194
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGT 205
LT+V ++ I+ V+GL+ K+ + DK H ++A
Sbjct: 195 TFFGGFIIGFTRGWKLTLV-ILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEV 253
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
+A I+T+ + ++ +++ EE L +K + A FL++ + + F+YG
Sbjct: 254 LAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYG 313
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP---- 321
+I ++G+++ +L + + I + AA +F +ID+ P
Sbjct: 314 TSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDS 373
Query: 322 --KSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
KS PD N +G +EF+++ +Y + + V LKG++ KVK G+ V + G G G
Sbjct: 374 FSKSGHKPD-----NIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCG 428
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAK 437
KS+ ++L+ R Y P G V IDG ++ I LR+I+ V QEP +F +I ENI +
Sbjct: 429 KSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGR 488
Query: 438 PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
+ T +E+E+A K A +DFI LP +DT+VGE+G +SGGQ+QRIA+ARA++ NPKI+
Sbjct: 489 EDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAHVSGGQKQRIAIARALVRNPKIL 548
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
LLD+ S LD E+E + L + + +T ++++ RLS V+ D + G IVE G
Sbjct: 549 LLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNH 608
Query: 558 EELIKKGGIFSEMM 571
+EL+++ GI+ +++
Sbjct: 609 DELMREKGIYFKLV 622
Score = 246 bits (622), Expect = 4e-64
Identities = 160/567 (28%), Positives = 297/567 (52%), Gaps = 21/567 (3%)
Query: 21 HFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR----YGLLILLVGVLNGVF 76
+F++G+F I+ V+ + + G + + + LL L++G+++ +
Sbjct: 706 YFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFIT 765
Query: 77 SLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITRFL 134
+ KA + LR F+++ R ++ +FD K +G L +R+ ND ++
Sbjct: 766 FFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAT 825
Query: 135 SFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDK 190
R+ ++ +I IIISL Y +TL ++A++ I + G+ + + + DK
Sbjct: 826 GSRLAVIFQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDK 883
Query: 191 IRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAP 250
+ IAT I +T+ SL+ E+ +T ++Q + Y +K + + +
Sbjct: 884 KELEGS--GKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFT 941
Query: 251 FLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAA 310
++ + + F +G + Q +T ++ + ++ + + D ++ +A
Sbjct: 942 QAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSA 1001
Query: 311 SRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPGE 366
S + +I+ P+ ID ++ + G ++F V Y T + VL+G+S +VK G+
Sbjct: 1002 SHIIRIIEKTPE-IDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQ 1060
Query: 367 KVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFN 426
+ + G G GKS++++L+ RFY P G V +DG + ++ + LR + V QEP +F+
Sbjct: 1061 TLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFD 1120
Query: 427 RSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRI 484
SI ENIA + + EE+ RAAK A IH FI SLP Y+T VG+KG LSGGQ+QRI
Sbjct: 1121 CSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRI 1180
Query: 485 ALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVI 544
A+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++++ RLS ++ D ++
Sbjct: 1181 AIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIV 1240
Query: 545 VMKDGKIVEDGKPEELIKKGGIFSEMM 571
V+++GK+ E G ++L+ + GI+ M+
Sbjct: 1241 VIQNGKVKEHGTHQQLLAQKGIYFSMV 1267
>pir||T22813 hypothetical protein F57A10.3 - Caenorhabditis elegans
>gi|3877814|emb|CAB09418.1| (Z96048) predicted using
Genefinder~contains similarity to Pfam domain: PF00005
(ABC transporter), Score=243.0, E-value=1.4e-69, N=1;
PF00664 (ABC transporter transmembrane region.),
Score=152.1, E-value=3.1e-42, N=1~cDNA EST EMBL:M75760
comes from thi>
Length = 733
Score = 249 bits (630), Expect = 5e-65
Identities = 159/516 (30%), Positives = 270/516 (51%), Gaps = 11/516 (2%)
Query: 66 ILLVGV-LNGVFSLAGR-YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
I L GV + G ++A R Y + A Q + LR F ++ R +M FFDK G+++SR+
Sbjct: 208 IALAGVFMLGAIAIAARIYCMHTAGQLVINDLRKSVFNSVLRQDMAFFDKNKVGEIVSRL 267
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
+ D + +S + ++ S MV ++ + V + + ++VG +
Sbjct: 268 STDALIVGYSVSMNLSDGARALITCFGSGGLMVYTSLAMCKVIFVVVPVIVGTFAVFGKL 327
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK-AMKI 242
R ++ +AT ++ ++T++ L E +S + E++ ++ K +
Sbjct: 328 QRKYTLMMQEAVAGANQVATERLSSVRTVRMLVAERKELAAYSDKINEIWQISKKEGLAK 387
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
++G+ F LA+S++ +YG I Q LT GEL +F Y + L A+ +
Sbjct: 388 GFMFGSFQFTGY-LALSSILFYGSNLISQGLLTYGELSSFCLYAVLSAGSLSAMSGFYLE 446
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKV 362
+ + L A+SRLF++ + P+ I V+I N + I F V Y + +SF V
Sbjct: 447 LMKGLGASSRLFELKNREPR-IPLEGGVQIGNVKDTIRFEHVAFGYADRDPLFHNISFDV 505
Query: 363 KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEP 422
G+ + G GSGKS+I L+ R Y PT G +L+DG ++ I R+ + V QEP
Sbjct: 506 PAGKITAVVGSSGSGKSTIASLLLRLYDPTSGRILVDGTDLKDIDPSYWRRHIGTVGQEP 565
Query: 423 FIFNRSIRENI---ALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
+F+ +I+ENI +L N T E+ AA + +FI+ P YDT VGE G TLSGG
Sbjct: 566 VLFSTTIKENIIYGSLEPENVTDAEIVSAADQSNADEFISRFPIKYDTKVGEHGSTLSGG 625
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQD--KTALIVSQRLSLV 537
Q+QRIA+ARA++ P I+++D+ S LDA +E + L ++L + +T +I++ RLS +
Sbjct: 626 QKQRIAIARALVNKPNILIMDEATSALDASSEYLVRIALNKLLANSKQTVMIIAHRLSTI 685
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
K D+++V+ G + E G +ELI GIF ++++
Sbjct: 686 KHADQIVVVDRGSVAESGSYDELIAIPDGIFRKLVE 721
>gb|AAG10628.1|AC022521_6 (AC022521) Putative ABC transporter [Arabidopsis thaliana]
Length = 1278
Score = 249 bits (630), Expect = 5e-65
Identities = 166/554 (29%), Positives = 281/554 (49%), Gaps = 11/554 (1%)
Query: 25 GLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLL 84
G+ L + ++ +N +K + KV +++ + L +G L F +++
Sbjct: 69 GMSLPFMTLLFGDLIDSFGKNQNNKDIVDVVSKVCLKF--VYLGLGTLGAAFLQVACWMI 126
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFD-KTFSGQLISRITNDTERITRFLSFRVRMLLY 143
Q A +R + I R ++ FFD +T +G+++ R++ DT I + +V +
Sbjct: 127 TGERQAA--RIRSTYLKTILRQDIGFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKFIQ 184
Query: 144 SIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIAT 203
+ + LT+V L +I ++ A+ V + + A++
Sbjct: 185 LVSTFVGGFVLAFIKGWLLTLVMLTSIPLLAMAGAAMALIVTRASSRGQAAYAKAATVVE 244
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
TI I+T+ S + E+ + + Y +++ T L F V + + +
Sbjct: 245 QTIGSIRTVASFTGEKQAINSYKKFITSAYKSSIQQGFSTGLGLGVMFFVFFSSYALAIW 304
Query: 264 YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKS 323
+GGK I++ T G ++ + ++ L + AAA ++F+ I P
Sbjct: 305 FGGKMILEKGYTGGAVINVIIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPL- 363
Query: 324 IDPPDA--VEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLITGPPGSGKS 379
ID D + + RG+IE +DV +Y + G S + G + G GSGKS
Sbjct: 364 IDAYDVNGKVLEDIRGDIELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKS 423
Query: 380 SILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPN 439
+++ LI RFY P G VLIDGVN+ + + + +R + V QEP +F+ SI ENIA K N
Sbjct: 424 TVISLIERFYDPKSGAVLIDGVNLKEFQLKWIRSKIGLVSQEPVLFSSSIMENIAYGKEN 483
Query: 440 ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLL 499
AT EE++ A ++A FI LP+G DT+VGE G LSGGQ+QRIA+ARA+L +P+I+LL
Sbjct: 484 ATVEEIKAATELANAAKFIDKLPQGLDTMVGEHGTQLSGGQKQRIAIARAILKDPRILLL 543
Query: 500 DDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEE 559
D+ S LDAE+E+ + E L ++ ++T +IV+ RLS V+ D + V+ GK+VE G E
Sbjct: 544 DEATSALDAESERVVQEALDRVMVNRTTVIVAHRLSTVRNADMIAVIHRGKMVEKGSHSE 603
Query: 560 LIKKG-GIFSEMMK 572
L+K G +S++++
Sbjct: 604 LLKDSEGAYSQLIR 617
Score = 243 bits (614), Expect = 4e-63
Identities = 158/527 (29%), Positives = 282/527 (52%), Gaps = 23/527 (4%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK--TFSGQL 119
+ ++ + +GV + + S YL A + +R F E+ +FD+ SG +
Sbjct: 752 WAIIFVALGVTSLIVSPTQMYLFAVAGGKLIRRIRSMCFEKAVHMEVAWFDEPQNSSGTM 811
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R++ D I + + + + ++ L + L ++ L+ + ++ G+N
Sbjct: 812 GARLSADATLIRALVGDALSLAVQNVASAASGLIIAFTASWELALIILVMLPLI-GINGF 870
Query: 180 YAMK-VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+K ++ + + + +A + I+T+ S EE V + ++ E +K
Sbjct: 871 VQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYKKQCEGPIKDGIK 930
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
I+ L F +L +T FY G + ++++ T V + + LTM A+G
Sbjct: 931 QGFISGLGFGFSFFILFCVYATSFYAGAR-LVEDGKTTFNNVFQVFFALTMA----AIGI 985
Query: 299 TIG-----DIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRGEIEFRDVWLTY--H 349
+ D ++ AA+ +F +ID K ID D + N +G+IE R + TY
Sbjct: 986 SQSSTFAPDSSKAKVAAASIFAIIDRKSK-IDSSDETGTVLENVKGDIELRHLSFTYPAR 1044
Query: 350 TGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTE 409
+ + + ++ G+ V + G GSGKS+++ L+ RFY P G + +DGV + K++ +
Sbjct: 1045 PDIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLQLK 1104
Query: 410 NLRKIVAYVPQEPFIFNRSIRENIALAKPN---ATQEEVERAAKIAKIHDFIASLPKGYD 466
LR+ + V QEP +FN +IR NIA K + AT+ E+ AA++A H FI+S+ +GYD
Sbjct: 1105 WLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYD 1164
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
TVVGE+GI LSGGQ+QR+A+ARA++ PKI+LLD+ S LDAE+E+ + + L ++ ++T
Sbjct: 1165 TVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRT 1224
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
++V+ RLS +K D + V+K+G I E G E LIK +GG+++ +++
Sbjct: 1225 TIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLIKIEGGVYASLVQ 1271
>pir||T28150 probable ATP-binding cassette transporter TAP1 - chicken
(fragment) >gi|3129972|emb|CAA18970.1| (AL023516)
Transport Associated Protein 1 [Gallus gallus]
Length = 557
Score = 248 bits (626), Expect = 1e-64
Identities = 145/515 (28%), Positives = 277/515 (53%), Gaps = 7/515 (1%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
L ++L+G+ + V L V L+ F A+ R + +G + R+
Sbjct: 26 LPMVLLGLSSAVTELVCDVTFVGTLSRTQSRLQRRVFAAVLRQSITELRADGAGDVAMRV 85
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
T D E + L + +LL+ + + M ++ + ++ + + +++ L
Sbjct: 86 TRDAEDVREALGEALSLLLWYLARGLCLFATMAWLSPRMALLTALALPLLLALPRAVGHF 145
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKI- 242
+ + +++ + +A T + T++S + E+ + Q ++ + L K + +
Sbjct: 146 RQALAPQMQKAQARASEVAVETFQAMATVRSFANEDGAAAHYRQRLQQSHRLEKKDVALY 205
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGD 302
TA + F L L M + YYGG+ + T++ G+LV FL Y + L L
Sbjct: 206 TASLWTSGFSALALKMGIL-YYGGQLVAAGTVSTGDLVTFLLYQIQFTDVLEVLLDYFPT 264
Query: 303 IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSF 360
+ +++ ++ ++F+ +D P+ + P + ++ +G ++ DVW +Y GR VLKGVS
Sbjct: 265 LMKAVGSSEKIFEFLDREPQ-VAPSGTMAPADLQGHLQLEDVWFSY-PGRQEPVLKGVSL 322
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+++PGE + + GPPG+GKS+++ L++R ++PT G +L+DG + + L + VA VPQ
Sbjct: 323 ELRPGEVLALLGPPGAGKSTLVALVSRLHQPTAGRLLLDGHPLPAYQHSYLCRQVAVVPQ 382
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
EP +F RS+ NI+ ++ +V AA+ HDFI LP+GYDT VGE G LSGGQ
Sbjct: 383 EPLLFARSLHANISYGLGGCSRAQVTAAARQVGAHDFITRLPQGYDTEVGELGGQLSGGQ 442
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEIL-QDKTALIVSQRLSLVKL 539
RQ +A+ARA+L +P+I++LD+ S LD E+++++ +++ + L+V+ R +L
Sbjct: 443 RQAVAIARALLRDPRILILDEHTSALDTESQQQVEQEILAAKGSGRAVLMVTGRAALAAR 502
Query: 540 VDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
+RV+V++ G++ ++G P E+++ G + + + G
Sbjct: 503 AERVVVLEGGEVRQEGPPHEVLRPGSLLRDWGQQG 537
>gb|AAD22645.1|AC007138_9 (AC007138) putative P-glycoprotein-like protein [Arabidopsis
thaliana] >gi|7268567|emb|CAB80676.1| (AL161493)
putative P-glycoprotein-like protein [Arabidopsis
thaliana]
Length = 1230
Score = 247 bits (625), Expect = 2e-64
Identities = 172/523 (32%), Positives = 274/523 (51%), Gaps = 25/523 (4%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD-KTFSGQLISR 122
L+ L +G L F +++ Q A +R + I R ++ FFD + +G+++ R
Sbjct: 78 LVYLGLGALGAAFLQVACWMITGERQAA--RIRSLYLKTILRQDIGFFDVEMTTGEVVGR 135
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
++ DT I + +V + I + LT+V L +I ++ A+
Sbjct: 136 MSGDTVLILDAMGEKVGKFIQLISTFVGGFVIAFLRGWLLTLVMLTSIPLLAMSGAAIAI 195
Query: 183 KVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKI 242
V + + +++ T+ I+T+ S + E+ + + + Y NVK +
Sbjct: 196 IVTRASSQEQAAYAKASNVVEQTLGSIRTVASFTGEKQAMSSYKELINLAYKSNVKQGFV 255
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALG----- 297
T L FLV + ++GG+ I++ T G A + M+T++ ALG
Sbjct: 256 TGLGLGVMFLVFFSTYALGTWFGGEMILRKGYTGG---AVINVMVTVVSSSIALGQASPC 312
Query: 298 ---FTIGDIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRGEIEFRDVWLTY--HT 350
FT G AAA ++F+ I+ P ID D + + RGEIE RDV +Y
Sbjct: 313 LTAFTAGK-----AAAYKMFETIEREPL-IDTFDLNGKVLEDIRGEIELRDVCFSYPARP 366
Query: 351 GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTEN 410
V G S + G + G GSGKS+++ LI RFY P G+VLIDGV++ + + +
Sbjct: 367 KEEVFGGFSLLIPSGTTTALVGESGSGKSTVISLIERFYDPNSGQVLIDGVDLKEFQLKW 426
Query: 411 LRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVG 470
+R + V QEP +F+ SI ENI K AT EE++ A+K+A FI LP G +T+VG
Sbjct: 427 IRGKIGLVSQEPVLFSSSIMENIGYGKEGATVEEIQAASKLANAAKFIDKLPLGLETLVG 486
Query: 471 EKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIV 530
E G LSGGQ+QRIA+ARA+L +P+I+LLD+ S LDAE+E+ + E L I+ ++T +IV
Sbjct: 487 EHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRIMVNRTTVIV 546
Query: 531 SQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
+ RLS V+ D + V+ GKIVE+G EL+K G +S++++
Sbjct: 547 AHRLSTVRNADIIAVIHRGKIVEEGSHSELLKDHEGAYSQLLR 589
Score = 245 bits (618), Expect = 1e-63
Identities = 157/524 (29%), Positives = 277/524 (51%), Gaps = 18/524 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK--TFSGQL 119
+ ++ +L+GV + YL A + +R F + E+ +FD+ SG +
Sbjct: 705 WSMIFVLLGVAAVIVYPTTNYLFAIAGGRLIRRIRSMCFEKVVHMEVGWFDEPGNSSGAM 764
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R++ D I + + + + ++ ++ L + + ++ L+ I + G+N
Sbjct: 765 GARLSADAALIRTLVGDSLCLSVKNVASLVTGLIIAFTASWEVAIIILVIIPFI-GINGY 823
Query: 180 YAMKVRPIYD---KIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLN 236
+K + K +++ + +A + I+T+ S EE V + + E+
Sbjct: 824 IQIKFMKGFSADAKAKYEEA--SQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSG 881
Query: 237 VKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELV-AFLTYMLTMMWPLRA 295
+K I+ + F VL ++ FY G + + ++ FL LT + +A
Sbjct: 882 IKQGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTLTAVGISQA 941
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRGEIEFRDVWLTYHTGRT 353
F D + AA +F +ID K ID D + + N +G+IE + TY T
Sbjct: 942 SSFA-PDSSKGKGAAVSIFRIIDRISK-IDSRDESGMVLENVKGDIELCHISFTYQTRPD 999
Query: 354 V--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENL 411
V + + ++ G+ V + G GSGKS+++ L+ RFY P G + +DGV + K++ + L
Sbjct: 1000 VQVFRDLCLSIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLRLKWL 1059
Query: 412 RKIVAYVPQEPFIFNRSIRENIALAK--PNATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
R+ + V QEP +FN +IR NIA K AT+ E+ A+++A H FI+S+ KGYDTVV
Sbjct: 1060 RQQMGLVGQEPVLFNDTIRANIAYGKGGEEATEAEIIAASELANAHRFISSIQKGYDTVV 1119
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
GE+GI LSGGQ+QR+A+ARA++ PKI+LLD+ S LDAE+E+ + + L ++ ++T ++
Sbjct: 1120 GERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTIV 1179
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
V+ RLS +K D + V+K+G I E G E LI +GG+++ +++
Sbjct: 1180 VAHRLSTIKNADVIAVVKNGVIAEKGTHETLINIEGGVYASLVQ 1223
>gb|AAD49436.1|AF083642_1 (AF083642) P-glycoprotein [Onchocerca volvulus]
Length = 1278
Score = 247 bits (624), Expect = 3e-64
Identities = 153/490 (31%), Positives = 264/490 (53%), Gaps = 17/490 (3%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
+R + +++ R E +FD+ +G L +++ + E+I + +V M+L + + + +
Sbjct: 143 MRQEYMKSLLRQEAAWFDQQKTGTLTAQLNANIEKIKDGIGDKVGMILRGVTMFLTCVII 202
Query: 155 MVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKS 214
+ LT+V T I L +T A ++ + G A++ +I +KT+ +
Sbjct: 203 GFIYDWRLTLVMFGTGPISAALLSTMARQMEHSSSMQSNTDGRAAAVLEESIMNVKTVAA 262
Query: 215 LSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKA----II 270
+ +E + +++ + + A + FLVL + + FYYG II
Sbjct: 263 CNAQETMIKRYAATLKACRKFALHAYAFAGFFDGLFFLVLYVFFAAGFYYGAYLYQIRII 322
Query: 271 QNT---LTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK-SIDP 326
N V L+ F +Y L ++ P + + + AA+ ++ +I+ P
Sbjct: 323 MNPGYIFAVANLIMFGSYNLGVLSP------HLMAVLNARVAAAVIYKIINRKPSFDSSS 376
Query: 327 PDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKL 384
D ++++ +GEIEF++V +Y + VL G+S+ KPG+ V + G G GKS+ L
Sbjct: 377 TDGMKVNEVKGEIEFQNVKFSYPKSKEHLVLNGLSWTAKPGDTVALVGHSGCGKSTSTGL 436
Query: 385 IARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEE 444
+ R Y G +LIDG+N+ I LR IV V QEP +F+ +I+ENI L K + T +E
Sbjct: 437 LTRLYNCNSGAILIDGINICDINIHTLRNIVGVVQQEPLLFSGTIKENIRLGKLDLTDQE 496
Query: 445 VERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVS 504
+ A KIA HDFI L +GYDT++G GI LSGGQ+QRIA+AR ++ NP+I+LLD+ S
Sbjct: 497 IIDACKIANAHDFINKLSEGYDTMIGAGGIQLSGGQKQRIAIARTIVRNPRILLLDEATS 556
Query: 505 NLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELI-KK 563
LDAE+E + LK+ +T +I++ RLS ++ +++IV+ G++ E G +EL K
Sbjct: 557 ALDAESEVIVQNALKKAFVGRTTIIIAHRLSTLRDSNQIIVLDKGQVAEIGTHKELCNNK 616
Query: 564 GGIFSEMMKA 573
GI++ ++K+
Sbjct: 617 DGIYASLVKS 626
Score = 222 bits (559), Expect = 1e-56
Identities = 159/573 (27%), Positives = 287/573 (49%), Gaps = 35/573 (6%)
Query: 11 LLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVG 70
L+S+LRG + + +F + + + + + ++ + + + I G+ L+V
Sbjct: 724 LVSFLRGLELPLFVLIFDLTFVVFAQAKLESVLERILPIAI------IYIALGIACLIV- 776
Query: 71 VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTE 128
+ + F+ A+ V LR+ A R + E+FD T + ++RI+ D +
Sbjct: 777 IFSATFTFGW------TAECVVDSLRLRAMRNMLYQNAEYFDTPSTSTAVTVTRISVDAQ 830
Query: 129 RITRFLSFRVRMLLYSI-FLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
+ R S + L+++++ + + L V ++ Y +V
Sbjct: 831 TLKRSRSANDANFDNIVAILVLVTIAVIFNWPVGLLAVKSPVTHFDADIDRKYNAEV--- 887
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYG 247
+K + V +A + I+TI+ ++ EE+ + Q E+L L K+ A+
Sbjct: 888 -NKCALKQIVTGQLALEIVEQIRTIQLITGEEHFHRLYVQTIEDLLYLQKKSSPYEAILF 946
Query: 248 --NAPFL----VLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
+ F+ ++ A Y G ++ Q T +A T W L + +
Sbjct: 947 AVTSSFMFFSDMISYAAGIALIYYGYSLPQEIFTASWSIA------TSGWALIMVSGCLN 1000
Query: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVLKGVS 359
+ A++ LF +I++ D + + G+++F + +Y T R VL G++
Sbjct: 1001 TFVMASPASNSLFRIINTGSDMNSVDDGLRPAIT-GDVQFNKIKFSYPTRPQRNVLNGLN 1059
Query: 360 FKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVP 419
G+ V +TGP GSGKS+++ L+ RFY+ G++ +D ++ KI LR+ +A V
Sbjct: 1060 LAAYAGQTVAVTGPSGSGKSTVIALLERFYRFNSGQLTLDDNSITKISLRYLREQIALVG 1119
Query: 420 QEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
QEP +F+ +I ENI L T +V A KIA I DFI + PKGYDT VGE G+ LSGG
Sbjct: 1120 QEPILFSGTILENILLGTTGKTLSDVREACKIANIIDFIETSPKGYDTEVGEHGVQLSGG 1179
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKL 539
Q+QRIA+ARA++ NPKI+LLD+ S LDAE E+ + + L +T + V+ RLS ++
Sbjct: 1180 QKQRIAIARALVRNPKILLLDEATSALDAECERTVQQALDAASSGRTCITVAHRLSSIQH 1239
Query: 540 VDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
D++ +++GK+VE+G +EL++ G ++++++
Sbjct: 1240 ADQIFFVENGKVVEEGTHQELVEFDGKYADLIR 1272
>pir||DVMS1A multidrug resistance protein 1a - mouse (fragment)
>gi|200330|gb|AAA03243.1| (M24417) mdr1a protein [Mus
musculus]
Length = 1104
Score = 246 bits (622), Expect = 4e-64
Identities = 160/567 (28%), Positives = 297/567 (52%), Gaps = 21/567 (3%)
Query: 21 HFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR----YGLLILLVGVLNGVF 76
+F++G+F I+ V+ + + G + + + LL L++G+++ +
Sbjct: 534 YFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFIT 593
Query: 77 SLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITRFL 134
+ KA + LR F+++ R ++ +FD K +G L +R+ ND ++
Sbjct: 594 FFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAT 653
Query: 135 SFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDK 190
R+ ++ +I IIISL Y +TL ++A++ I + G+ + + + DK
Sbjct: 654 GSRLAVIFQNIANLGTGIIISLIY--GWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDK 711
Query: 191 IRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAP 250
+ IAT I +T+ SL+ E+ +T ++Q + Y +K + + +
Sbjct: 712 KELEGS--GKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFT 769
Query: 251 FLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAA 310
++ + + F +G + Q +T ++ + ++ + + D ++ +A
Sbjct: 770 QAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSA 829
Query: 311 SRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGRT--VLKGVSFKVKPGE 366
S + +I+ P+ ID ++ + G ++F V Y T + VL+G+S +VK G+
Sbjct: 830 SHIIRIIEKTPE-IDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQ 888
Query: 367 KVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFN 426
+ + G G GKS++++L+ RFY P G V +DG + ++ + LR + V QEP +F+
Sbjct: 889 TLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFD 948
Query: 427 RSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRI 484
SI ENIA + + EE+ RAAK A IH FI SLP Y+T VG+KG LSGGQ+QRI
Sbjct: 949 CSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRI 1008
Query: 485 ALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVI 544
A+ARA++ P I+LLD+ S LD E+EK + E L + + +T ++++ RLS ++ D ++
Sbjct: 1009 AIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIV 1068
Query: 545 VMKDGKIVEDGKPEELIKKGGIFSEMM 571
V+++GK+ E G ++L+ + GI+ M+
Sbjct: 1069 VIQNGKVKEHGTHQQLLAQKGIYFSMV 1095
Score = 229 bits (577), Expect = 8e-59
Identities = 136/419 (32%), Positives = 232/419 (54%), Gaps = 15/419 (3%)
Query: 162 LTMVALITIAIVVGLNTTYAMKVRPIY-DKIRHQTGVIASIATGTIAGIKTIKSLSVEEN 220
LT+V ++ I+ V+GL+ K+ + DK H ++A +A I+T+ + ++
Sbjct: 38 LTLV-ILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKK 96
Query: 221 VQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELV 280
+++ EE L +K + A FL++ + + F+YG +I ++G+++
Sbjct: 97 ELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVL 156
Query: 281 AFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP------KSIDPPDAVEISN 334
+L + + I + AA +F +ID+ P KS PD N
Sbjct: 157 TVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPD-----N 211
Query: 335 PRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPT 392
+G +EF+++ +Y + + V LKG++ KVK G+ V + G G GKS+ ++L+ R Y P
Sbjct: 212 IQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPL 271
Query: 393 KGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIA 452
G V IDG ++ I LR+I+ V QEP +F +I ENI + + T +E+E+A K A
Sbjct: 272 DGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEA 331
Query: 453 KIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEK 512
+DFI LP +DT+VGE+G +SGGQ+QRIA+ARA++ NPKI+LLD+ S LD E+E
Sbjct: 332 NAYDFIMKLPHQFDTLVGERGAHVSGGQKQRIAIARALVRNPKILLLDEATSALDTESEA 391
Query: 513 KLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
+ L + + +T ++++ RLS V+ D + G IVE G +EL+++ GI+ +++
Sbjct: 392 VVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLV 450
>sp|Q02592|HMT1_SCHPO HEAVY METAL TOLERANCE PROTEIN PRECURSOR >gi|2370465|emb|CAB11609.1|
(Z98951) heavy metal tolerance protein precursor
[Schizosaccharomyces pombe]
Length = 830
Score = 246 bits (621), Expect = 6e-64
Identities = 157/585 (26%), Positives = 293/585 (49%), Gaps = 29/585 (4%)
Query: 3 KSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRN---AIDKGVSTGAYKVA 59
+S + L+ L + + + F I F+ I++ + V +L + + ++ + K+
Sbjct: 244 RSFSTLLPYLWPTKDYRLQFQI--FICIVLLFLGRAVNILAPRQLGVLTEKLTKHSEKIP 301
Query: 60 IRYGLLILLVGVLNGVFSLAGR---YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
+L ++ L G + G +L V +QYA + A R + +F +
Sbjct: 302 WSDVILFVIYRFLQGNMGVIGSLRSFLWVPVSQYAYRAISTKALRHVLNLSYDFHLNKRA 361
Query: 117 GQLISRITNDTERIT--RFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVV 174
G++++ +T + T + F++ +L + + ++ Y+ ++ +I T++ LI
Sbjct: 362 GEVLTALTKGSSLNTFAEQVVFQIGPVLLDLGVAMV--YFFIKFDIYFTLIVLIMTLCYC 419
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFS-------- 226
+ K+ + ++ I +T+K+ ++ ++
Sbjct: 420 YVTVKITSWRTEARRKMVNSWRESYAVQNDAIMNFETVKNFDADDFENERYGHAVDIYLK 479
Query: 227 QENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYM 286
QE + L+SLN + + G L +A Y + TVG+ V LTYM
Sbjct: 480 QERKVLFSLNF----LNIVQGGIFTFSLAIACLLSAY----RVTFGFNTVGDFVILLTYM 531
Query: 287 LTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWL 346
+ + PL G +Q S+ RL ++ + P ++ P+A ++ +G++ F V
Sbjct: 532 IQLQQPLNFFGTLYRSLQNSIIDTERLLEIFEEKPTVVEKPNAPDLKVTQGKVIFSHVSF 591
Query: 347 TYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
Y + VL ++F +PG+ + + G G GKS+I++++ RF+ G + ID ++ +
Sbjct: 592 AYDPRKPVLSDINFVAQPGKVIALVGESGGGKSTIMRILLRFFDVNSGSITIDDQDIRNV 651
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
+LR + VPQ+ +FN +I NI AKP+AT EE+ AAK A+IHD I P GY+
Sbjct: 652 TLSSLRSSIGVVPQDSTLFNDTILYNIKYAKPSATNEEIYAAAKAAQIHDRILQFPDGYN 711
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
+ VGE+G+ LSGG++QR+A+ARA+L +P I+LLD+ S LD TE+++ L + +T
Sbjct: 712 SRVGERGLKLSGGEKQRVAVARAILKDPSIILLDEATSALDTNTERQIQAALNRLASGRT 771
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKK-GGIFSEM 570
A++++ RLS + D ++ + +G+IVE G EELIK+ GG + +M
Sbjct: 772 AIVIAHRLSTITNADLILCISNGRIVETGTHEELIKRDGGAYKKM 816
>gb|AAG10627.1|AC022521_5 (AC022521) Putative ABC transporter [Arabidopsis thaliana]
Length = 1229
Score = 245 bits (619), Expect = 1e-63
Identities = 162/561 (28%), Positives = 283/561 (49%), Gaps = 11/561 (1%)
Query: 25 GLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLL 84
G+ L ++ ++ +N +K + KV +++ + L +G L F +++
Sbjct: 12 GVCLPLMTLLFGDLIDSFGKNQNNKDIVDVVSKVCLKF--VYLGLGRLGAAFLQVACWMI 69
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFD-KTFSGQLISRITNDTERITRFLSFRVRMLLY 143
Q A +R + + I R ++ FFD +T +G+++ R++ DT I + +V +
Sbjct: 70 TGERQAAK--IRSNYLKTILRQDIGFFDVETNTGEVVGRMSGDTVHIQDAMGEKVGKFIQ 127
Query: 144 SIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIAT 203
+ + LT+V L +I + A+ V + + A++
Sbjct: 128 LVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAMALLVTRASSRGQAAYAKAATVVE 187
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
TI I+T+ S + E+ + + Y +++ T L V + + +
Sbjct: 188 QTIGSIRTVASFTGEKQAINSYKKYITSAYKSSIQQGFSTGLGLGVMIYVFFSSYALAIW 247
Query: 264 YGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKS 323
+GGK I++ T G ++ + ++ L + AAA ++F+ I P
Sbjct: 248 FGGKMILEKGYTGGSVINVIIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPL- 306
Query: 324 IDPPDA--VEISNPRGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLITGPPGSGKS 379
ID D + + RG+IE +DV +Y + G S + G + G GSGKS
Sbjct: 307 IDAYDVNGKVLGDIRGDIELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKS 366
Query: 380 SILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPN 439
+++ LI RFY P GEVLIDG+N+ + + + +R + V QEP +F+ SI ENIA K N
Sbjct: 367 TVINLIERFYDPKAGEVLIDGINLKEFQLKWIRSKIGLVCQEPVLFSSSIMENIAYGKEN 426
Query: 440 ATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLL 499
AT +E++ A ++A FI +LP+G DT VGE G LSGGQ+QRIA+ARA+L +P+++LL
Sbjct: 427 ATLQEIKVATELANAAKFINNLPQGLDTKVGEHGTQLSGGQKQRIAIARAILKDPRVLLL 486
Query: 500 DDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEE 559
D+ S LD E+E+ + E L ++ ++T ++V+ RLS V+ D + V+ GK+VE G E
Sbjct: 487 DEATSALDTESERVVQEALDRVMVNRTTVVVAHRLSTVRNADMIAVIHSGKMVEKGSHSE 546
Query: 560 LIKKG-GIFSEMMKAGGVYGG 579
L+K G +S++++ + G
Sbjct: 547 LLKDSVGAYSQLIRCQEINKG 567
Score = 242 bits (612), Expect = 6e-63
Identities = 157/527 (29%), Positives = 281/527 (52%), Gaps = 23/527 (4%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK--TFSGQL 119
+ ++ + +GV + + S + YL A + ++ F E+ +FD+ SG +
Sbjct: 703 WAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSGTM 762
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R++ D I + + + + + L + L ++ L+ + ++ G+N
Sbjct: 763 GARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPLI-GINGF 821
Query: 180 YAMK-VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+K ++ + + + +A + I+T+ S EE V ++++ E VK
Sbjct: 822 LQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGPIKDGVK 881
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
I+ L F +L +T FY + + T ++ + LTM A+G
Sbjct: 882 QGFISGLGFGFSFFILFCVYATSFYAAARLVEDGKTTFIDVFQVF-FALTMA----AIGI 936
Query: 299 TIG-----DIQRSLAAASRLFDVIDSAPKSIDPPD--AVEISNPRGEIEFRDVWLTY--H 349
+ D ++ AA+ +F +ID K ID D + N +G+IE R + TY
Sbjct: 937 SQSSTFAPDSSKAKVAAASIFAIIDRKSK-IDSSDETGTVLENVKGDIELRHLSFTYPAR 995
Query: 350 TGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTE 409
G + + + ++ G+ V + G GSGKS+++ L+ RFY P G++ +DGV + K++ +
Sbjct: 996 PGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQLK 1055
Query: 410 NLRKIVAYVPQEPFIFNRSIRENIALAKPN---ATQEEVERAAKIAKIHDFIASLPKGYD 466
LR+ + V QEP +FN +IR NIA K + AT+ E+ AA++A H FI+S+ +GYD
Sbjct: 1056 WLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYD 1115
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
TVVGEKGI LSGGQ+QR+A+ARA++ PKI+LLD+ S LDAE+E+ + + L ++ ++T
Sbjct: 1116 TVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNRT 1175
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK-KGGIFSEMMK 572
++V+ RLS +K D + ++K+G I E+G E LIK GG+++ +++
Sbjct: 1176 TVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIKIDGGVYASLVQ 1222
>pir||S25198 vacuolar membrane protein HMT1 - fission yeast
(Schizosaccharomyces pombe) >gi|4972|emb|CAA78419.1|
(Z14055) HMT1 [Schizosaccharomyces pombe]
Length = 830
Score = 245 bits (618), Expect = 1e-63
Identities = 157/585 (26%), Positives = 293/585 (49%), Gaps = 29/585 (4%)
Query: 3 KSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRN---AIDKGVSTGAYKVA 59
+S + L+ L + + + F I F+ I++ + V +L + + ++ + K+
Sbjct: 244 RSFSTLLPYLWPTKDYRLQFQI--FICIVLLFLGRAVNILAPRQLGVLTEKLTKHSEKIP 301
Query: 60 IRYGLLILLVGVLNGVFSLAGR---YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
+L ++ L G + G +L V +QYA + A R + +F +
Sbjct: 302 WSDVILFVIYRFLQGNMGVIGSLRSFLWVPVSQYAYRAISTKALRHVLNLSYDFHLNKRA 361
Query: 117 GQLISRITNDTERIT--RFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVV 174
G++++ +T + T + F++ +L + + ++ Y+ ++ +I T++ LI
Sbjct: 362 GEVLTALTKGSSLNTFAEQVVFQIGPVLLDLGVAMV--YFFIKFDIYFTLIVLIMTLCYC 419
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFS-------- 226
+ K+ + ++ I +T+K+ ++ ++
Sbjct: 420 YVTVKITSWRTEARRKMVNTWRESYAVQNDAIMNFETVKNFDADDFENERYGHAVDIYLK 479
Query: 227 QENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYM 286
QE + L+SLN + + G L +A Y + TVG+ V LTYM
Sbjct: 480 QERKVLFSLNF----LNIVQGGIFTFSLAIACLLSAY----RVTFGFNTVGDFVILLTYM 531
Query: 287 LTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWL 346
+ + PL G +Q S+ RL ++ + P ++ P+A ++ +G++ F V
Sbjct: 532 IQLQQPLNFFGTLYRSLQNSIIDTERLLEIFEEKPTVVEKPNAPDLKVTQGKVIFSHVSF 591
Query: 347 TYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
Y + VL ++F +PG+ + + G G GKS+I++++ RF+ G + ID ++ +
Sbjct: 592 AYDPRKPVLSDINFVAQPGKVIALVGESGGGKSTIMRILLRFFDVNSGSITIDDQDIRNV 651
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
+LR + VPQ+ +FN +I NI AKP+AT EE+ AAK A+IHD I P GY+
Sbjct: 652 TLSSLRSSIGVVPQDSTLFNDTILYNIKYAKPSATNEEIYAAAKAAQIHDRILQFPDGYN 711
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
+ VGE+G+ LSGG++QR+A+ARA+L +P I+LLD+ S LD TE+++ L + +T
Sbjct: 712 SRVGERGLKLSGGEKQRVAVARAILKDPSIILLDEATSALDTNTERQIQAALNRLASGRT 771
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKK-GGIFSEM 570
A++++ RLS + D ++ + +G+IVE G EELIK+ GG + +M
Sbjct: 772 AIVIAHRLSTITNADLILCISNGRIVETGTHEELIKRDGGRYKKM 816
>pir||T06165 multidrug resistance protein 1 homolog - barley
>gi|2292907|emb|CAA71179.1| (Y10099) P-glycoprotein
homologue [Hordeum vulgare]
Length = 1232
Score = 243 bits (615), Expect = 3e-63
Identities = 157/510 (30%), Positives = 280/510 (54%), Gaps = 21/510 (4%)
Query: 75 VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITR 132
V S+ G Y + ++ V +R AI R E+ FFD + + ++I+ I+ D I
Sbjct: 98 VASMEG-YCWSRTSERQVLRIRHLYLEAILRQEVAFFDSQEATTSEIINSISKDASLIQE 156
Query: 133 FLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVA--LITIAIVVGLNTTYAMKVRPIYDK 190
LS +V + L + + L + + L +V+ L+ + I+ GL Y + + +
Sbjct: 157 VLSEKVPLFLMHSTVFVSGLAFSTYFSWRLALVSYPLVLLLIIPGL--IYGKYLLYLSRE 214
Query: 191 IRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAP 250
R + S+ + IKT+ S + E+ + +++ ++ +L +K L
Sbjct: 215 SRREYAKANSLVEQALGSIKTVYSFTAEKGIIQRYTAILDKTINLGIKQGIAKGLA--VG 272
Query: 251 FLVLGLAM-STMFYYGGKAIIQNTLTVGELVAF-LTYMLTMMWPLRALGFTIGDIQRSL- 307
F L A+ + + +YG + ++ + + G + A ++++L + +LG + +++ +
Sbjct: 273 FTGLSFAIWAFLAWYGSRLVMYHHESGGRIYAAGISFVLGGL----SLGMALPELKHFIE 328
Query: 308 --AAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKGVSFKV 362
AA+R+ + I+ P+ + D P + + RGEIEF + Y + TVLK + ++
Sbjct: 329 ASVAATRILERINRVPQINDDDPKGLVLDQVRGEIEFESIRFVYPSRPNMTVLKDFNLQI 388
Query: 363 KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEP 422
G+ + + G GSGKS+ + L+ RFY ++G V +DG+++ K+ +++R + V Q+
Sbjct: 389 PAGQTIALVGSSGSGKSTAIALVQRFYDASEGTVKVDGIDIKKLNLKSIRSKIGLVSQDH 448
Query: 423 FIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQ 482
+F SI+ENI KP+AT + + AA A H+FI LP+GY+T +GE+G LSGGQ+Q
Sbjct: 449 ALFGTSIKENILFGKPDATMDLLYAAAMTANAHNFIMGLPEGYETKIGERGALLSGGQKQ 508
Query: 483 RIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDR 542
RIA+ARA+L NP I+LLD+ S LD+E+EK + L + +T L+V+ +LS VK D+
Sbjct: 509 RIAIARAVLKNPAILLLDEATSALDSESEKLVQHALDQASMGRTTLVVAHKLSTVKNADQ 568
Query: 543 VIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
+ V+ G+I E G +ELI KGG +S ++K
Sbjct: 569 IAVVDGGRIAEIGTHDELINKGGPYSRLVK 598
Score = 242 bits (612), Expect = 6e-63
Identities = 164/521 (31%), Positives = 269/521 (51%), Gaps = 21/521 (4%)
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK--TFSGQ 118
RY L+ + +++ +L Y ++ V +R+ I E +FD+ SG
Sbjct: 711 RYALIFCSLSLVSIAVNLLQHYNFAYMGEHLVRRIRVQVLEKILTFEAAWFDEDTNSSGS 770
Query: 119 LISRITNDTERITRFLSFRVRMLLYSI--FLIIISLYYMVRMNITLTMVALITIAIVVGL 176
L SR+++++ + ++ R+ +LL + +I +++ +V + L M+A+ ++
Sbjct: 771 LCSRLSDESSLVKTLVADRISLLLQTACGIVIAVTMGLIVAWKLALVMIAVQPCTMIC-- 828
Query: 177 NTTYAMKV--RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEE-LY 233
YA K+ + + IA + + + S + F EE L
Sbjct: 829 --YYAKKIVLSNVSRDLAKAQYESTQIAIEAVYNHRMVTSFGCSSKILQLFEHTQEEPLR 886
Query: 234 SLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL 293
K+ G +P L L+ + F+YGGK ++ G++ +++ +
Sbjct: 887 KARKKSWVAGITTGLSPCLTF-LSWALDFWYGGKLAQSGEISAGDVFKTFFVLVSTGKLI 945
Query: 294 RALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDA-VEISNPR----GEIEFRDVWLTY 348
G D+ + A + +F+V+D KSI P ++ VE NP+ G IEF+ V +Y
Sbjct: 946 ADAGSMTSDLAKGANAVASVFEVLDR--KSISPQNSQVEKDNPKSKIQGRIEFKKVDFSY 1003
Query: 349 HTGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
T +L+ S VK G + + G G GKS+I+ LI RFY +G V IDGV+V ++
Sbjct: 1004 PTRPQCLILQDFSLDVKAGTSIGLVGRSGCGKSTIIGLIQRFYDVDRGAVRIDGVDVREM 1063
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
R A V QEP +F+ S+R+NIA KP A +EE+ AAK A H+FI+SL GYD
Sbjct: 1064 NVLWYRGFTALVSQEPAMFSGSVRDNIAFGKPEADEEEIVEAAKAANAHEFISSLKDGYD 1123
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T GE GI LSGGQ+QRIA+ARA++ NP I+LLD+ S LDA++E+ + E L I+ +T
Sbjct: 1124 TDCGEHGIQLSGGQKQRIAIARAIIRNPAILLLDEATSALDAQSEQVVQEALDRIMTGRT 1183
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIF 567
+IV+ RL+ +K D + + +GK++E G +L+ K G F
Sbjct: 1184 TIIVAHRLNTIKNADSIAFLGEGKVIERGTYPQLMNKKGAF 1224
>pir||A35391 hetA protein - Anabaena sp
Length = 607
Score = 243 bits (614), Expect = 4e-63
Identities = 159/567 (28%), Positives = 294/567 (51%), Gaps = 9/567 (1%)
Query: 3 KSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNA-IDKGVSTGAYKVA-- 59
+ I L + S+L IG L L T+ P+ + +D ++ A+ +
Sbjct: 29 RKIAILAVIFSFLAASFEGVSIGFLLSFLQKLTSPNDPIQTGISWVDMILAADAWPIPPI 88
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
R LLILL + F+ G A L F +Q + +F +T SG+L
Sbjct: 89 YRISLLILLSTWMRATFNYFGGVYTESAQLNLADRLHKQIFEQLQALRLSYFAQTRSGEL 148
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVA-LITIAIVVGLNT 178
I+ IT + ERI + S + +L I + + M ++ L++++ LI + + VGL+T
Sbjct: 149 INTITTEIERIKQGFS-GLAFVLTRIMTVCVYFVVMFSISWQLSIISVLIFLLLAVGLST 207
Query: 179 TYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+VR I H ++A I GI+TI++ +E + +F + + LN
Sbjct: 208 LNK-RVRETSFGISHANAQFTAVAVEFINGIRTIQAFGTQEFERQRFYKASTN--QLNA- 263
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
A+K+ + + G+A + + + TL V L+ F ++ ++ ++ +
Sbjct: 264 AIKVVLAWTLVKPIAEGIATTVLISLIVISFATFTLPVASLLTFFFVLVRVIPNIQDING 323
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGV 358
T+ + ++ + +++ + K + + I+ V Y VL +
Sbjct: 324 TVAFLSTLQGSSENIKNILQTNNKPYLKNGKLHFQGLKRSIDLVSVDFGYTADNLVLNNI 383
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
+ ++ G+ + G G+GK+++ LI RFY PT+G++L+DG++V + +LR+ +A V
Sbjct: 384 TLTIERGKTTALVGASGAGKTTLADLIPRFYDPTEGQILVDGLDVQYFEINSLRRKMAVV 443
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
Q+ FIFN SIR+NIA A++ E+ A++A FI +P+G+DT +G++G+ LSG
Sbjct: 444 SQDTFIFNTSIRDNIAYGTSGASEAEIREVARLANALQFIEEMPEGFDTKLGDRGVRLSG 503
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
GQRQRIA+ARA+L +P+I++LD+ S LD+ +E+ + E ++++ +T + ++ RLS +
Sbjct: 504 GQRQRIAIARALLRDPEILILDEATSALDSVSERLIQESIEKLSVGRTVIAIAHRLSTIA 563
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGG 565
D+V+VM+ G+IVE G +EL+++ G
Sbjct: 564 KADKVVVMEQGRIVEQGNYQELLEQRG 590
>pir||A42150 P-glycoprotein pgp1 - Arabidopsis thaliana
>gi|3849833|emb|CAA43646.1| (X61370) P-glycoprotein
[Arabidopsis thaliana]
>gi|4883607|gb|AAD31576.1|AC006922_8 (AC006922) putative
ABC transporter [Arabidopsis thaliana]
Length = 1286
Score = 243 bits (613), Expect = 5e-63
Identities = 163/534 (30%), Positives = 279/534 (51%), Gaps = 36/534 (6%)
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD-KTFSGQ 118
++Y L L+VG S A + + + +R+ A +++FFD + +
Sbjct: 87 LKYALYFLVVGAAIWASSWAEISCWMWSGERQTTKMRIKYLEAALNQDIQFFDTEVRTSD 146
Query: 119 LISRITND--------TERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITI 170
++ I D +E++ F+ + + S F++ + + + + +TL +V LI
Sbjct: 147 VVFAINTDAVMVQDAISEKLGNFIHYMATFV--SGFIVGFTAVWQLAL-VTLAVVPLI-- 201
Query: 171 AIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE 230
A++ G++TT K+ +K + +I T+ I+ + + E +S +
Sbjct: 202 AVIGGIHTTTLSKLS---NKSQESLSQAGNIVEQTVVQIRVVMAFVGESRASQAYSSALK 258
Query: 231 ELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM 290
L K + A + V+ + + +YGG ++++ LT G L + M
Sbjct: 259 IAQKLGYKTGLAKGMGLGATYFVVFCCYALLLWYGGY-LVRHHLTNGGLA------IATM 311
Query: 291 WPLRALGFTIGDIQRSLAA-------ASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFR 342
+ + G +G S+AA A+++F +ID P + VE+ + G +E +
Sbjct: 312 FAVMIGGLALGQSAPSMAAFAKAKVAAAKIFRIIDHKPTIERNSESGVELDSVTGLVELK 371
Query: 343 DVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDG 400
+V +Y + V L V G+ + + G GSGKS+++ LI RFY P G+VL+DG
Sbjct: 372 NVDFSYPSRPDVKILNNFCLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPNSGQVLLDG 431
Query: 401 VNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIAS 460
++ +K LR+ + V QEP +F SI+ENI L +P+A Q E+E AA++A H FI
Sbjct: 432 QDLKTLKLRWLRQQIGLVSQEPALFATSIKENILLGRPDADQVEIEEAARVANAHSFIIK 491
Query: 461 LPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKE 520
LP G+DT VGE+G+ LSGGQ+QRIA+ARAML NP I+LLD+ S LD+E+EK + E L
Sbjct: 492 LPDGFDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDR 551
Query: 521 ILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKG--GIFSEMMK 572
+ +T LI++ RLS ++ D V V++ G + E G +EL KG G++++++K
Sbjct: 552 FMIGRTTLIIAHRLSTIRKADLVAVLQQGSVSEIGTHDELFSKGENGVYAKLIK 605
Score = 219 bits (551), Expect = 9e-56
Identities = 143/492 (29%), Positives = 256/492 (51%), Gaps = 20/492 (4%)
Query: 95 LRMDAFRAIQRHEMEFFDK--TFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISL 152
+R A+ ++EM +FD+ S ++ +R+ D + + R+ +++ + L++++
Sbjct: 776 VREKMLSAVLKNEMAWFDQEENESARIAARLALDANNVRSAIGDRISVIVQNTALMLVAC 835
Query: 153 YYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTI 212
+ L +V + +VV M + + +A IA ++T+
Sbjct: 836 TAGFVLQWRLALVLVAVFPVVVAATVLQKMFMTGFSGDLEAAHAKGTQLAGEAIANVRTV 895
Query: 213 KSLSVEENVQTKFSQENEE-LYSLNVKAMKITALYGNAPFLV-----LGLAMSTMFYYGG 266
+ + E + ++ E L K + YG A F + LGL ++ G
Sbjct: 896 AAFNSEAKIVRLYTANLEPPLKRCFWKGQIAGSGYGVAQFCLYASYALGLWYASWLVKHG 955
Query: 267 KAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK-SID 325
+ T+ V F+ M++ L I+ A S +F+++D + D
Sbjct: 956 ISDFSKTIRV-----FMVLMVSANGAAETLTLAPDFIKGGQAMRS-VFELLDRKTEIEPD 1009
Query: 326 PPDAVEISNP-RGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSIL 382
PD + + RGE+E + + +Y + + + +S + + G+ + + GP G GKSS++
Sbjct: 1010 DPDTTPVPDRLRGEVELKHIDFSYPSRPDIQIFRDLSLRARAGKTLALVGPSGCGKSSVI 1069
Query: 383 KLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQ 442
LI RFY+P+ G V+IDG ++ K + +RK +A VPQEP +F +I ENIA AT+
Sbjct: 1070 SLIQRFYEPSSGRVMIDGKDIRKYNLKAIRKHIAIVPQEPCLFGTTIYENIAYGHECATE 1129
Query: 443 EEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
E+ +AA +A H FI++LP+GY T VGE+G+ LSGGQ+QRIA+ARA++ +I+LLD+
Sbjct: 1130 AEIIQAATLASAHKFISALPEGYKTYVGERGVQLSGGQKQRIAIARALVRKAEIMLLDEA 1189
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK 562
S LDAE+E+ + E L + +T+++V+ RLS ++ + V+ DGK+ E G L+K
Sbjct: 1190 TSALDAESERSVQEALDQACSGRTSIVVAHRLSTIRNAHVIAVIDDGKVAEQGSHSHLLK 1249
Query: 563 K--GGIFSEMMK 572
GI++ M++
Sbjct: 1250 NHPDGIYARMIQ 1261
>gb|AAA66476.1| (L26286) SMDR1 [Schistosoma mansoni]
Length = 691
Score = 243 bits (613), Expect = 5e-63
Identities = 177/584 (30%), Positives = 291/584 (49%), Gaps = 41/584 (7%)
Query: 23 LIGLFLIILMS-----YTNSIVPVLIRNAID-KGVSTGAYKVAIRYGLLILLVGVLNGVF 76
++G F+ +M+ Y V L R + +G + Y +R LL + F
Sbjct: 106 ILGAFVAAVMNVYIPLYLGDFVSSLSRCVVTHEGFVSAVYVPTLRLCSSYLLQSL--STF 163
Query: 77 SLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSF 136
G LL + +R+ FR + ++ +FD SG+L+ I +D +
Sbjct: 164 LYIG--LLGSVGERMARRMRIQLFRKLVYQDVAYFDVHSSGKLVEIIGSDVQNFKSSFKQ 221
Query: 137 RVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTG 196
+ L + ++ S++ ++ ++ TLT + + V + + ++R I +++ Q
Sbjct: 222 CISQGLRNGIQVVGSVFALLSISPTLTAALIGCLPCVFLIGSLMGTELRHISREVQSQNS 281
Query: 197 VIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK-AMKITALYGNAPFLVLG 255
+ AS+ + I+T+KSL++E+ + K + ++ L+ K + I + G + + G
Sbjct: 282 LFASLIDEAFSHIRTVKSLAMEDFLINKINYNVDKAKMLSEKLSFGIGSFQGLSNLTLNG 341
Query: 256 LAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFD 315
+ + + Y GG + + L G L++FL T+ L L G + R A R+ D
Sbjct: 342 VVLGVL-YVGGHLMSRGELDAGHLMSFLATTQTLQRSLTQLSLLYGQVVRGYTALKRIHD 400
Query: 316 V------IDSAPKSIDP--------------PDAVEISNPRGEIEFRDVWLTY--HTGRT 353
+ I S P S P + S P IEF DV Y
Sbjct: 401 ILALPSGIGSIPSSSSSLVVSKQHVNNIKELPSSSIYSAP--SIEFSDVKFAYPNRPETI 458
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR- 412
VL +S + G+ + + G G+GKS+++ L+ RFY P GE+L++G + LR
Sbjct: 459 VLNELSMFLPGGKVIALVGQSGAGKSTVVSLLERFYDPISGEILLNGDKLTNFNVNYLRS 518
Query: 413 KIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIAS-LPKGYDTVVGE 471
K++ Y+ QEP IFN SIRENI + +AT EEVE AAK+A HDFI++ LP GYDT+VG+
Sbjct: 519 KLIGYISQEPQIFNASIRENIRFGRFDATDEEVEEAAKLAYAHDFISNDLPYGYDTLVGQ 578
Query: 472 KGIT---LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
T LSGGQRQRIA+AR +L N I+L+D+ S LD E+E K+ L ++ +T L
Sbjct: 579 GTGTIAGLSGGQRQRIAIARILLKNAPILLMDEATSALDTESEAKVQNALNNAMKGRTVL 638
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
I++ RLS V+ D ++VM G+IVE G EL+ G + +++
Sbjct: 639 IIAHRLSTVRKADLILVMSKGQIVEKGTHSELMANHGYYYNLVQ 682
>pir||E82539 ABC transporter ATP-binding protein XF2582 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107799|gb|AAF85379.1|AE004065_4 (AE004065) ABC
transporter ATP-binding protein [Xylella fastidiosa]
Length = 564
Score = 243 bits (613), Expect = 5e-63
Identities = 158/561 (28%), Positives = 279/561 (49%), Gaps = 5/561 (0%)
Query: 15 LRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNG 74
+R H F L + + S +P + ID G S+ R L+LLV V+
Sbjct: 1 MRRHLALFSGWLIALAVSSAATLTLPSAFKQMIDHGFSSEGQ--INRTFALLLLVAVILA 58
Query: 75 VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFL 134
V + A + + + + LR + + + F D+ S +L+SR+ D+E + +
Sbjct: 59 VGTAARLFSVSLLGEKIITDLRSHLYAHLIGLDASFHDRNRSNELVSRLATDSELLRSII 118
Query: 135 SFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQ 194
+ + S I SL + + L ++L+ I +V+ A ++ + +
Sbjct: 119 GSTMSVATRSTVTAIGSLIMLFITSPRLASLSLVVIPLVILPIVLGAQHLQKAARTSQDR 178
Query: 195 TGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVL 254
S A T+ ++T+++ + E +T+F + E + + I A +++
Sbjct: 179 IADTNSFAAETLRALRTVQAYAREHYERTRFDRTLETSLQAARQRIHIQTWVTAASIVLI 238
Query: 255 GLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLF 314
A+ + + G +I ++ G L F+ Y L + AL ++QR+ R+F
Sbjct: 239 FSAIVGVLWAGAHDVIAGRMSAGTLGEFVLYALIGGGSIGALAEVWNELQRAAGGMGRIF 298
Query: 315 DVIDSAPKSIDPPDAVEISNP-RGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLIT 371
+++ P + P RGEI F V Y L + ++PGE +
Sbjct: 299 ELLKEKNTLTVPATPALLPQPLRGEIRFERVGFHYPQRPETPALDDIDLHIRPGETIAFV 358
Query: 372 GPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRE 431
GP G+GKS++L L+ RFY PT G +LIDGV++ + + LR +A V Q+P +F S E
Sbjct: 359 GPSGAGKSTLLSLLLRFYDPTHGRILIDGVDLRQTDPKVLRTHIALVQQQPTLFTASAME 418
Query: 432 NIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAML 491
NI + +AT E+E A++ ++ FI +LP+ Y T +GE G++LSGGQ+QRIA+ARA+L
Sbjct: 419 NIRYGRLDATTAEIEIASRSSEADGFIRALPQSYATELGEHGMSLSGGQQQRIAIARALL 478
Query: 492 MNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKI 551
I+LLD+ + LDA+ E+ + + L+ ++ +T LI++ RL + DR++VM G+I
Sbjct: 479 KEAPILLLDEATNALDAQNEQAVQQALERLMTGRTTLIIAHRLVTILKADRIVVMDQGRI 538
Query: 552 VEDGKPEELIKKGGIFSEMMK 572
V G ELI GG+++++ +
Sbjct: 539 VAQGTHSELIAAGGLYAKLAR 559
>sp|Q03727|COMA_STRPN TRANSPORT ATP-BINDING PROTEIN COMA >gi|520738|gb|AAA69510.1|
(M36180) comA protein [Streptococcus pneumoniae]
Length = 717
Score = 242 bits (612), Expect = 6e-63
Identities = 157/573 (27%), Positives = 293/573 (50%), Gaps = 7/573 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
+ + I +L RG + ++ L+ +++ S +++ ID V
Sbjct: 151 KNGLLSFIPILVKQRGLIANIVLATLLVTVINIVGSYY---LQSIIDTYVPDQMRSTLGI 207
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
+ +++V +L + S A YLL+ Q + + + + M FF +G+++S
Sbjct: 208 ISIGLVIVYILQQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVS 267
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R T+ I S + + L ++IISL + N L + L+ + I + +
Sbjct: 268 RFTDANSIIDALASTILSIFLDVSTVVIISLV-LFSQNTNLFFMTLLALPIYTVIIFAFM 326
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ V++S I GI+TIKSL+ E K +E + + +
Sbjct: 327 KPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSR 386
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
+ + L + + G ++ +++G+L+ + T ++ PL +
Sbjct: 387 AESQQKALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQT 446
Query: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFK 361
+Q + A +RL +V A + + ++S +G++ F+ V Y GR VL ++
Sbjct: 447 KLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLT 506
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
V G KV G GSGK+++ K++ FY P++GE+ + GVN+ +I + LR+ + Y+PQ+
Sbjct: 507 VPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ 566
Query: 422 PFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
P++FN +I EN+ L AK TQE++ RA ++A+I + I +P Y T + G +SGGQ
Sbjct: 567 PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQ 626
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
RQRIALARA+L + +++LD+ S+LD TEK++V++L I DKT + ++ RL++ +
Sbjct: 627 RQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNL--IALDKTLIFIAHRLTIAERT 684
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
++V+V+ GKIVE+GK +L+ +GG ++ ++ +
Sbjct: 685 EKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS 717
>pir||A39203 comA protein - Streptococcus pneumoniae
Length = 717
Score = 242 bits (611), Expect = 9e-63
Identities = 157/573 (27%), Positives = 293/573 (50%), Gaps = 7/573 (1%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
+ + I +L RG + ++ L+ +++ S +++ ID V
Sbjct: 151 KNGLLSFIPILVKQRGLIANIVLATLLVTVINIVGSYY---LQSIIDTYVPDQMRSTLGI 207
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
+ +++V +L + S A YLL+ Q + + + + M FF +G+++S
Sbjct: 208 ISIGLVIVYILQQILSYAQEYLLLVLGQPLSIDVILSYIKHVFHLPMSFFATRRTGEIVS 267
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R T+ I S + + L ++IISL + N L + L+ + I + +
Sbjct: 268 RFTDANSIIDALASTILSIFLDVSTVVIISLV-LFSQNTNLFFMTLLALPIYTVIIFAFM 326
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ V++S I GI+TIKSL+ E K +E + + +
Sbjct: 327 KPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSR 386
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
+ + L + + G ++ +++G+L+ + T ++ PL +
Sbjct: 387 AESQQKALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQT 446
Query: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFK 361
+Q + A +RL +V A + + ++S +G++ F+ V Y GR VL ++
Sbjct: 447 KLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLT 506
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
V G KV G GSGK+++ K++ FY P++GE+ + GVN+ +I + LR+ + Y+PQ+
Sbjct: 507 VPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ 566
Query: 422 PFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
P++FN +I EN+ L AK TQE++ RA ++A+I + I +P Y T + G +SGGQ
Sbjct: 567 PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQ 626
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
RQRIALARA+L + +++LD+ S+LD TEK++V++L I DKT + ++ RL++ +
Sbjct: 627 RQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNL--IALDKTLIFIAHRLTIAERT 684
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
++V+V+ GKIVE+GK +L+ +GG ++ ++ +
Sbjct: 685 EKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS 717
>sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49 (P-GLYCOPROTEIN 49)
>gi|103251|pir||A41249 multidrug resistance protein
homolog Mdr49 - fruit fly (Drosophila melanogaster)
>gi|157871|gb|AAA28679.1| (M59076) P glycoprotein
[Drosophila melanogaster]
Length = 1302
Score = 242 bits (611), Expect = 9e-63
Identities = 164/599 (27%), Positives = 293/599 (48%), Gaps = 39/599 (6%)
Query: 7 QLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYG--- 63
+ + ++S L A I F+II +T+ +L+ + G S+ A+ + + G
Sbjct: 43 RFLLVVSLLVATAASAFIPYFMIIYGEFTS----LLVDRTVGVGTSSPAFALPMFGGGQQ 98
Query: 64 ----------LLILLVGVLNGVFSLAGR---YLLV--------KAAQYAVYYLRMDAFRA 102
I+ G+ SL G +LL+ + A + +R A
Sbjct: 99 LTNASKEENNQAIIDDATAFGIGSLVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEA 158
Query: 103 IQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITL 162
+ R ++ ++D + S++T D +++ + ++ ++++ I +I + L
Sbjct: 159 MLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKL 218
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
T+V L + ++ + A + +K A++ +GI+T+ + S +E +
Sbjct: 219 TLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEK 278
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGEL--- 279
+F + + K + + +L++ L M+ +YG I+ +
Sbjct: 279 ERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILDERDLPDRVYTP 338
Query: 280 VAFLTYMLTMMWPLRALGFTIGDIQR---SLAAASRLFDVIDSAPKSIDPPDAV--EISN 334
+ + ++ + LGF ++ + AA LF++ID P +DP D N
Sbjct: 339 AVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDR-PSQVDPMDEKGNRPEN 397
Query: 335 PRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPT 392
G I F + Y V LKG++ V PG+ V G G GKS++++L+ RFY P
Sbjct: 398 TAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPE 457
Query: 393 KGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIA 452
G V +DG ++ + LR + V QEP +F +I ENI +P+ATQ ++E+AA+ A
Sbjct: 458 AGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAA 517
Query: 453 KIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEK 512
HDFI LPKGYDT VGEKG +SGGQ+QRIA+ARA++ P+++LLD+ S LD +EK
Sbjct: 518 NCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEK 577
Query: 513 KLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ L+ Q T L+V+ RLS + D+++ +KDG + E G EEL+++ G++ E++
Sbjct: 578 RVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMERRGLYCELV 636
Score = 237 bits (599), Expect = 2e-61
Identities = 153/528 (28%), Positives = 277/528 (51%), Gaps = 26/528 (4%)
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSG 117
++ ++ + +G++ G+ ++ Y+ A LR AF I ++ +FD + G
Sbjct: 776 LKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVG 835
Query: 118 QLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIV---V 174
L SR+ +D + RV +L ++ +++ + + T++ L+T+ +V V
Sbjct: 836 ALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSV 895
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
L + MK K + + +A I I+T+ L +E V ++ Q+ + +
Sbjct: 896 YLEGRFIMKSA---QKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDV 952
Query: 235 LNVKAMK----ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM 290
+ ++ + AL APFL G++M YYGG + + + +++ ++
Sbjct: 953 ACRRKVRFRGLVFALGQAAPFLAYGISM----YYGGILVAEERMNYEDIIKVAEALIFGS 1008
Query: 291 WPL-RALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAV--EISNPRGEIEFRDVWLT 347
W L +AL + ++ ++ +A RL D+ +PP + + G+I + +V
Sbjct: 1009 WMLGQALAYA-PNVNDAILSAGRLMDLFKRTSTQPNPPQSPYNTVEKSEGDIVYENVGFE 1067
Query: 348 YHT--GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAK 405
Y T G +L+G++ +K V + GP GSGKS+ ++L+ R+Y P G V + GV +
Sbjct: 1068 YPTRKGTPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTE 1127
Query: 406 IKTENLRKIVAYVPQEPFIFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLP 462
+ LR + V QEP +F+R+I ENIA + + + +E+ AAK + IH+FI++LP
Sbjct: 1128 FPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALP 1187
Query: 463 KGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEIL 522
+GYDT +G K LSGGQ+QRIA+ARA++ NPKI++LD+ S LD E+EK + + L E
Sbjct: 1188 QGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDEAR 1246
Query: 523 QDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+T L ++ RL+ V+ D + V+K G +VE G +EL+ I++ +
Sbjct: 1247 SGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGTHDELMALNKIYANL 1294
>gb|AAF58437.1| (AE003820) Mdr49 gene product [Drosophila melanogaster]
Length = 1279
Score = 242 bits (611), Expect = 9e-63
Identities = 164/599 (27%), Positives = 293/599 (48%), Gaps = 39/599 (6%)
Query: 7 QLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYG--- 63
+ + ++S L A I F+II +T+ +L+ + G S+ A+ + + G
Sbjct: 43 RFLLVVSLLVATAASAFIPYFMIIYGEFTS----LLVDRTVGVGTSSPAFALPMFGGGQQ 98
Query: 64 ----------LLILLVGVLNGVFSLAGR---YLLV--------KAAQYAVYYLRMDAFRA 102
I+ G+ SL G +LL+ + A + +R A
Sbjct: 99 LTNASKEENNQAIIDDATAFGIGSLVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEA 158
Query: 103 IQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITL 162
+ R ++ ++D + S++T D +++ + ++ ++++ I +I + L
Sbjct: 159 MLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKL 218
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
T+V L + ++ + A + +K A++ +GI+T+ + S +E +
Sbjct: 219 TLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEK 278
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGEL--- 279
+F + + K + + +L++ L M+ +YG I+ +
Sbjct: 279 ERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILDERDLPDRVYTP 338
Query: 280 VAFLTYMLTMMWPLRALGFTIGDIQR---SLAAASRLFDVIDSAPKSIDPPDAV--EISN 334
+ + ++ + LGF ++ + AA LF++ID P +DP D N
Sbjct: 339 AVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDR-PSQVDPMDEKGNRPEN 397
Query: 335 PRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPT 392
G I F + Y V LKG++ V PG+ V G G GKS++++L+ RFY P
Sbjct: 398 TAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPE 457
Query: 393 KGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIA 452
G V +DG ++ + LR + V QEP +F +I ENI +P+ATQ ++E+AA+ A
Sbjct: 458 AGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAA 517
Query: 453 KIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEK 512
HDFI LPKGYDT VGEKG +SGGQ+QRIA+ARA++ P+++LLD+ S LD +EK
Sbjct: 518 NCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEK 577
Query: 513 KLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
++ L+ Q T L+V+ RLS + D+++ +KDG + E G EEL+++ G++ E++
Sbjct: 578 RVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMERRGLYCELV 636
Score = 237 bits (599), Expect = 2e-61
Identities = 153/528 (28%), Positives = 277/528 (51%), Gaps = 26/528 (4%)
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSG 117
++ ++ + +G++ G+ ++ Y+ A LR AF I ++ +FD + G
Sbjct: 753 LKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVG 812
Query: 118 QLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIV---V 174
L SR+ +D + RV +L ++ +++ + + T++ L+T+ +V V
Sbjct: 813 ALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSV 872
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
L + MK K + + +A I I+T+ L +E V ++ Q+ + +
Sbjct: 873 YLEGRFIMKSA---QKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDI 929
Query: 235 LNVKAMK----ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM 290
+ ++ + AL APFL G++M YYGG + + + +++ ++
Sbjct: 930 ACRRKVRFRGLVFALGQAAPFLAYGISM----YYGGILVAEERMNYEDIIKVAEALIFGS 985
Query: 291 WPL-RALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAV--EISNPRGEIEFRDVWLT 347
W L +AL + ++ ++ +A RL D+ +PP + + G+I + +V
Sbjct: 986 WMLGQALAYA-PNVNDAILSAGRLMDLFKRTSTQPNPPQSPYNTVEKSEGDIVYENVGFE 1044
Query: 348 YHT--GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAK 405
Y T G +L+G++ +K V + GP GSGKS+ ++L+ R+Y P G V + GV +
Sbjct: 1045 YPTRKGTPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTE 1104
Query: 406 IKTENLRKIVAYVPQEPFIFNRSIRENIALA---KPNATQEEVERAAKIAKIHDFIASLP 462
+ LR + V QEP +F+R+I ENIA + + + +E+ AAK + IH+FI++LP
Sbjct: 1105 FPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALP 1164
Query: 463 KGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEIL 522
+GYDT +G K LSGGQ+QRIA+ARA++ NPKI++LD+ S LD E+EK + + L E
Sbjct: 1165 QGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDEAR 1223
Query: 523 QDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
+T L ++ RL+ V+ D + V+K G +VE G +EL+ I++ +
Sbjct: 1224 SGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGTHDELMALNKIYANL 1271
>pir||T19982 hypothetical protein C47A10.1 - Caenorhabditis elegans
>gi|3875004|emb|CAB03973.1| (Z81484) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=450.7,
E-value=4.2e-132, N=2; PF00664 (ABC transporter
transmembrane region.), Score=399.8, E-value=8.4e-117,
N=2~cDNA EST yk303b9.3 comes from this gene~cDNA EST
yk303b9.5 c> >gi|3879215|emb|CAB07855.1| (Z93782)
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=450.7, E-value=4.2e-132, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=399.8, E-value=8.4e-117, N=2~cDNA EST yk303b9.3
comes from this gene~cDNA EST yk303b9.5 c>
Length = 1294
Score = 242 bits (610), Expect = 1e-62
Identities = 154/485 (31%), Positives = 258/485 (52%), Gaps = 11/485 (2%)
Query: 96 RMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLII--ISLY 153
R F ++ R E+ ++DK SG L +++ ++ ER+ +V + + I ++
Sbjct: 139 RRQFFHSVMRQEIAWYDKNTSGTLSNKLFDNLERVREGTGDKVGLAFQMMAQFIGGFAVA 198
Query: 154 YMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIK 213
+ +TL M++L ++ GL A + K Q V IA + I+T+
Sbjct: 199 FTYDWLLTLIMMSLSPFMMICGL--FLAKLLATAATKEAKQYAVAGGIAEEVLTSIRTVI 256
Query: 214 SLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNT 273
+ + +E ++ E +K + + F+++ + F+ G +
Sbjct: 257 AFNGQEYECKRYEDALEHGKKTGIKKSFLIGAGLASFFVIIYASYCLAFWVGTNFVYSGR 316
Query: 274 LTVGE-LVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAV 330
L G L F + M+ M L G I +L AA+ L++VID P+ ID +
Sbjct: 317 LESGTVLTVFFSVMMGSM-ALGQAGQQFATIGTALGAAASLYEVIDRIPE-IDAYSTEGQ 374
Query: 331 EISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARF 388
S G I V TY T V LKGVS +PG+ V + G G GKS+I++L+ RF
Sbjct: 375 TPSKISGRISVNKVEFTYPTRADVKILKGVSLDAQPGQTVALVGSSGCGKSTIIQLLQRF 434
Query: 389 YKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA 448
Y P G++LID + + + LR++V V QEP +FN SI +NI + + + E++ RA
Sbjct: 435 YNPDAGQILIDDIPIEDFNIKYLRQLVGVVSQEPNLFNTSIEQNIRYGRSDVSDEDIARA 494
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
K A DFI + P+G +T+VG++G+ +SGGQ+QRIA+ARA++ NPKI+LLD+ S LDA
Sbjct: 495 LKEANAADFIKTFPEGLNTLVGDRGVQMSGGQKQRIAIARALVRNPKILLLDEATSALDA 554
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFS 568
E+E + L+ + +T ++++ RLS V+ D++IVMK G+++E G E LI++ G++
Sbjct: 555 ESESIVQSALENASRGRTTIVIAHRLSTVRNADKIIVMKAGQVMEVGTHETLIEQKGLYH 614
Query: 569 EMMKA 573
E++ A
Sbjct: 615 ELVHA 619
Score = 221 bits (558), Expect = 1e-56
Identities = 166/583 (28%), Positives = 282/583 (47%), Gaps = 35/583 (6%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMS--------YTNSIVPVLIRNAIDKGVSTGAYKVA 59
L ++L Y R ++ + ++ + + I+ V D+ G +
Sbjct: 692 LFKILRYARPEWIYIFFAIIAALIQGAVMPAFSLFFSQIINVFSNPDRDQMKKDGHF--- 748
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSG 117
+ L+ L++ + G L L AA+ +R +R + R + +FD K G
Sbjct: 749 --WALMFLVLAAVQGTSMLFQCSLFGVAAERLTMRIRSKVYRNVLRQDATYFDMPKHSPG 806
Query: 118 QLISRITNDTERITRFLSFRVRMLLYSIFLII----ISLYYMVRMNITLTMVALITIAIV 173
++ +R+ D I + +R+ + +I + I+ YY +M L M +A+
Sbjct: 807 RITTRLATDAPNIKSAIDYRLGSIFNAIASVGGGLGIAFYYGWQMAF-LVMAIFPFMAVG 865
Query: 174 VGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELY 233
L Y K G A A I I+T+++L+++ + F + +
Sbjct: 866 QALMMKYHGGSATSDAKEMENAGKTAMEA---IENIRTVQALTLQTKLYNIFCSHLDAPH 922
Query: 234 SLNVKAMKITAL-YGNAPFLVLGLAMSTMFYYGGKAII-QNTLTVGELVAFLTYMLTMMW 291
N+ I L YG A + + F +G I +N L E V L + + +
Sbjct: 923 GGNISKAIIRGLTYGFANSIQF-FTYAAAFRFGLFLIFDKNVLMEPENV--LRVLFAISF 979
Query: 292 PLRALGFTIG---DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY 348
+GF + ++ AA +F++++ P+ + GE++ V+ Y
Sbjct: 980 SFGTIGFAASYFPEYIKATFAAGLIFNMLEEEPRIDGMTSSGTYPQLSGEVKLNKVFFRY 1039
Query: 349 --HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
+L+G++ VKPG+ + + GP G GKS+++ L+ R Y P +G V +D ++ ++
Sbjct: 1040 PERPAVPILQGLNVHVKPGQTLALVGPSGCGKSTVISLLERLYDPLEGAVTVDNNDLRQM 1099
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIA--LAKPNATQEEVERAAKIAKIHDFIASLPKG 464
++LRK +A V QEP +F+ SIRENI L T E++E A A IH FI LP G
Sbjct: 1100 NPKHLRKHIALVSQEPILFDTSIRENIVYGLQPGEYTHEQIETACSKANIHKFIDELPDG 1159
Query: 465 YDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQD 524
Y+T VGEKG LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD E+EK++ L +D
Sbjct: 1160 YETRVGEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTESEKQVQVALDAAAKD 1219
Query: 525 KTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIF 567
+T ++V+ RLS + ++V+K+G++VE G ELI K G +
Sbjct: 1220 RTCIVVAHRLSTIVNAGCIMVVKNGQVVEQGTHNELIAKRGAY 1262
>pir||C81352 lipid export ABC transport protein Cj0803 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968249|emb|CAB73068.1| (AL139076) lipid export ABC
transport protein [Campylobacter jejuni]
Length = 580
Score = 242 bits (610), Expect = 1e-62
Identities = 167/576 (28%), Positives = 303/576 (51%), Gaps = 32/576 (5%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNS-----IVPVLIRNAIDKGVSTGAYKVAIRY 62
LIR + + + F I +F +IL S + + P+L ++K A+ Y
Sbjct: 11 LIRFKPFYKRYWKQFAIAIFGMILASGGTAGSFYALEPILNYIFVEKNE-------ALLY 63
Query: 63 GLLILLVGVLNGVFSLAGRYLLVKAAQYA----VYYLRMDAFRAIQRHEMEFFDKTFSGQ 118
+ LLV L F G YL + + LR + + R +M+FF + SG+
Sbjct: 64 TVPFLLV--LMYFFKNLGTYLQSFYVSFIGTDMLRVLRARVLKNVLRLDMDFFKRYRSGE 121
Query: 119 LISRITNDTERITRFLSFRV----RMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVV 174
L+SR TND + +S + R LL +I L+ + LY + TL AL+ + + +
Sbjct: 122 LVSRCTNDINALQSIVSNIIPDFFRELLTAIGLLAVVLY----QSPTLAFFALVILPLAI 177
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
+A K++ I+ + S + I+ IK+ E+ KF++ N+ L
Sbjct: 178 FPLVWFAKKLKKYARNIQETNSDLLSYLGEIFSNIELIKANDNEKKESDKFAKHNDTLCK 237
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
LN+K+ +I AL ++ + ++ + GG+ +I +++VG ++F++ + + PL+
Sbjct: 238 LNLKSARIDALTSPLMDMMGSVGVAVVIIVGGREVINGSMSVGSFISFVSALFAIYTPLK 297
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY-HTGRT 353
L G +Q ++AA+ R F ++D P+ + E+ N +I F +V Y + ++
Sbjct: 298 RLSSLYGKLQGAVAASERTFYLLDLEPQI--KGGSKELKNIE-KISFENVEFAYENPHKS 354
Query: 354 VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRK 413
VLKGV+F G+ + + G G GKSSI+ L+ FY+ KG++L++ +++ E+L
Sbjct: 355 VLKGVNFDFVKGQMLALVGTSGGGKSSIINLLMYFYEKQKGKILLNQEDISTFTIESLHA 414
Query: 414 IVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ V Q ++FN S NIA ++ +E+V +A K+A ++F+ + G V E G
Sbjct: 415 KIGLVTQNIYLFNDSFAANIAYSE-ELEEEKVIQALKLANAYEFVKEM-GGIWAEVKEHG 472
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
LSGGQ+QRIA+ARA+ NP +++ D+ S LD E+EK +V+ ++ + QD+ L+V+ R
Sbjct: 473 KNLSGGQKQRIAIARALYKNPDVLIFDEATSALDNESEKAIVKTIENLKQDRLILVVAHR 532
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSE 569
LS ++ D+++V+ GK++ GK EEL++ ++ +
Sbjct: 533 LSTIENADKIVVLDKGKVLAIGKDEELLQTCSLYQK 568
>sp|Q10418|MESD_LEUME MESENTERICIN Y105 TRANSPORT ATP-BINDING PROTEIN MESD
>gi|1075664|pir||S52205 mesI protein - Leuconostoc
mesenteroides >gi|609084|emb|CAA57402.1| (X81803) mesD
[Leuconostoc mesenteroides]
Length = 722
Score = 241 bits (608), Expect = 2e-62
Identities = 173/577 (29%), Positives = 303/577 (51%), Gaps = 21/577 (3%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
++S+ I +++ + ++ +I L+ L+S S ++ ID +
Sbjct: 156 KRSLTSFIPVITRQKLLVINIVIAALLVTLVSILGSYY---LQGIIDTYIPNNMKNTLGI 212
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
L ++ V+ + S A YLL+ Q + + + I M FF +G+++S
Sbjct: 213 VSLGLIFAYVIQQLLSYARDYLLIVMGQRLSIDIILSYIKHIFELPMSFFATRRTGEIVS 272
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITI---AIVVGLNT 178
R T+ I S + + L L+I+ +V+ N TL +++LI I A+VV L
Sbjct: 273 RFTDANAIIEALASTMLSVFLDLGILVIVGTVLVVQ-NSTLFLISLIAIPAYALVVWLFM 331
Query: 179 TYAMKVRPIYDKIRHQTG-VIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
K+ + + Q G +++S I G++TIK+L+ E K E +
Sbjct: 332 RPFSKM----NNDQMQAGSMLSSSIIEDINGVETIKALNSEATAYHKIDHEFVTYLEKSF 387
Query: 238 KAMKITALYGNAPFLVLGLAMSTMFYY-GGKAIIQNTLTVGELVAFLTYMLTMMWPLRAL 296
K A+ NA +L L+++ + + G + ++ N ++VG+L+ + + PL+ +
Sbjct: 388 VYAKTEAVQ-NAIKSLLQLSLNVVILWVGAQLVMTNKISVGQLITYNALLGFFTDPLQNI 446
Query: 297 GFTIGDIQRSLAAASRLFDV--IDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+Q++ A +RL +V +DS K D E P + + Y G
Sbjct: 447 INLQTKLQQASVANNRLNEVYLVDSEFK--DSHQMTEKITPNSSLVADHITYKYGFGAPA 504
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
+ VS + GEK+ + G GSGKS+++KL+ F++P G + + +A + LR
Sbjct: 505 IDDVSLTITAGEKIALVGISGSGKSTLVKLLVNFFQPESGTISLGPTPLANLDKHELRGH 564
Query: 415 VAYVPQEPFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ Y+PQEPFIF+ SI EN+ L AKP TQE++ RA +IA+I D I + +G+ T + E G
Sbjct: 565 INYLPQEPFIFSGSIMENLLLGAKPGTTQEDIIRAVEIAEIKDDIEKMSQGFGTELAESG 624
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+SGGQ+QRIALARA+L++ +++LD+ SNLD TEKK++++L + L +KT + V+ R
Sbjct: 625 -NISGGQKQRIALARAILVDSPVLILDESTSNLDVLTEKKIIDNLMK-LTEKTIIFVAHR 682
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
L++ + VDR++ M+ GKI+EDG + L+K GG ++ +
Sbjct: 683 LTISQRVDRILTMQSGKIIEDGTHDTLLKAGGFYASL 719
>emb|CAA88940.2| (Z49126) contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=430.2, E-value=6.2e-126, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=141.7, E-value=4.1e-39, N=2 [Caenorhabditis
elegans]
Length = 1239
Score = 241 bits (608), Expect = 2e-62
Identities = 152/515 (29%), Positives = 272/515 (52%), Gaps = 12/515 (2%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
+G++IL++ ++ GV G ++ + +R + A+ R + + DK SG +
Sbjct: 129 FGVIILVLALIQGVCIQRGTSRILDS-------IRKEFLGAVLRQDANWLDKHSSGSITC 181
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
++ + E I+ L + ML+ + S+ +N LT + T+ V
Sbjct: 182 QLNENIEVISDGLGNKCCMLVRGFAMFTSSIIACAFINWQLTFITF-TMGPVSAFVLHLL 240
Query: 182 MKVRPIY-DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
KV + +++ + +I +I ++T++S + + + TK +Q NE++ K+
Sbjct: 241 TKVNEVSNEELMSLSAQSHAIIEESILNVRTVQSCNGQNFMITKLNQVNEKIKKFYNKST 300
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTL-TVGELVAFLTYMLTMMWPLRALGFT 299
+ V+ ++G + + G+++ + + + L LG
Sbjct: 301 FWAGFFDGLALFVIYFITGISLFFGCRLYFNQEIGKAGDVILIVNTICVTGYFLGLLGPH 360
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT-GRTVLKGV 358
+ +Q++ + L+ I+SAPKS ++IS+ RG IEFRDV Y T VL+G+
Sbjct: 361 MSSLQQAATSFLLLYKTIESAPKSEGKEGEIKISSTRGNIEFRDVRFKYFTRDNEVLQGL 420
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
S +V PG+ V + G G GKS+ + L+ + Y+ ++GE+LIDG N+ + ++LR+ + V
Sbjct: 421 SLQVLPGQTVALVGTSGCGKSTSIGLLTKLYRASEGEILIDGKNIDMLDAKSLRQQIGIV 480
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
QEP +F+ +I ENI L + N +E ++ AA IA FI L GY+T +G G+ LSG
Sbjct: 481 QQEPKLFDGTIMENIKLGR-NVDEETIKTAADIANASSFIEKLENGYETRLGPGGVQLSG 539
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
GQ+QRI +ARA++ +P I+LLD+ S LD+ E + + L + + +T +I++ RLS +K
Sbjct: 540 GQKQRICIARALVTSPSILLLDEATSALDSHNEHIVNKALTKASEGRTTIIIAHRLSSLK 599
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
VDR+ V+ GK E G +ELI GGI++ + K+
Sbjct: 600 SVDRIYVLDQGKTKEIGTHDELILLGGIYARLAKS 634
Score = 187 bits (470), Expect = 3e-46
Identities = 140/517 (27%), Positives = 245/517 (47%), Gaps = 37/517 (7%)
Query: 76 FSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITRF 133
F YL A + ++ + + + +FD +T +SRI +
Sbjct: 737 FKTLQMYLCGWLANEVMNEVKQEMLSEVLNKPIPYFDNPETSPSACVSRIISHAHNCYAC 796
Query: 134 LSFRVRMLLY----SIFLIIISLYYMVRMNIT-LTMVALITIAIVVGLNTTY-AMKVRPI 187
L R ++ +IF ++++ ++ + + L + L+TI + ++ + A + +
Sbjct: 797 LDHRAIRFVWFIAGTIFSLLLAFPFVWELGVLGLGITILLTIFSLHFVSVAHRAHSEKSV 856
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQ--ENEELYSLNVKAMK---- 241
DK A + I+ IK L+VE + KFS+ + E+Y + +
Sbjct: 857 MDKS-------GEFAVEIVEHIRAIKLLAVEGYFENKFSEYLKTSEIYENKIGFVSSLNF 909
Query: 242 -ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMM--WPLRALGF 298
IT Y A ++L + + Y+G + + FL + M W +
Sbjct: 910 AITQSYVFACDMLLFFVGTLLIYHGRYSPDK---------VFLAFNGAQMSAWGVMYFSP 960
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVLK 356
+I R A+A+++F D + + G++E DV Y + R V +
Sbjct: 961 WFPEIVRGSASANQIFSFFDK--NRTNSTSGLSKPEINGKVEVSDVTFAYPSTPHRNVCE 1018
Query: 357 GVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVA 416
G S + G + + G G GKS+I+ ++ RFY G + +D ++ I +LR ++
Sbjct: 1019 GFSLNIPKGHSIALVGASGCGKSTIISMLERFYSAKAGRISVDDNDIDGIDVNHLRNNIS 1078
Query: 417 YVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITL 476
V QEP +FN +IRENI + + EEV++A K A FI S P GYDT+VGE G +L
Sbjct: 1079 VVGQEPVLFNATIRENITIGIDEVSVEEVQKACKAANAAGFIESFPLGYDTIVGEGGASL 1138
Query: 477 SGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSL 536
SGGQ+QRIA+ARA++ PKI+LLD+ S LD ++E+ + + L+ +T++IV+ RLS
Sbjct: 1139 SGGQKQRIAIARAIIRKPKILLLDEATSALDTQSEEIVQKALRSATTGRTSIIVAHRLST 1198
Query: 537 VKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
V+ D + + G + E G EL+ ++ ++ A
Sbjct: 1199 VQHCDTIYYISRGAVAEYGTHAELVAMDSKYARLVAA 1235
>gb|AAB49750.1| (U63741) multidrug resistance protein LmrA [Lactococcus lactis]
Length = 590
Score = 240 bits (605), Expect = 4e-62
Identities = 149/576 (25%), Positives = 296/576 (50%), Gaps = 21/576 (3%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIR---NAIDKGVSTGAYKV 58
+ SI ++L+ + + F+IG+ I+ + VP +++ N+ GV+ G KV
Sbjct: 18 KTSIKHFVKLIRAAKPRYLFFVIGIVAGIIGTLIQLQVPKMVQPLINSFGHGVNGG--KV 75
Query: 59 AIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQ 118
A+ ++ L +G + S +L + V LR + + +++FD+ +G+
Sbjct: 76 AL---VIALYIG--SAAVSAIAAIVLGIFGESVVKNLRTRVWDKMIHLPVKYFDEVKTGE 130
Query: 119 LISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLN- 177
+ SR+ NDT ++ ++ + SI L++ S+ +M++M LT+ +I + IV+ +
Sbjct: 131 MSSRLANDTTQVKNLIANSIPQAFTSILLLVGSIIFMLQMQWRLTLAMIIAVPIVMLIMF 190
Query: 178 --TTYAMKVR-PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
T+ K+ D + + G IA+ +++ I+ +KS + E+ K + LY
Sbjct: 191 PIMTFGQKIGWTRQDSLANFQG----IASESLSEIRLVKSSNAEKQASKKAENDVNALYK 246
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
+ VK L L + L + + YG I +++G L+ + Y++ ++ +
Sbjct: 247 IGVKEAVFDGLMSPVMMLSMMLMIFGLLAYGIYLISTGVMSLGTLLGMMMYLMNLIGVVP 306
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+ ++ ++ + RL +++D + + D++++ + V Y +
Sbjct: 307 TVATFFTELAKASGSTGRLTELLDEEQEVLHQGDSLDLEGKT--LSAHHVDFAYDDSEQI 364
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
L +SF+ +P + GP G GKS+I L+ RFY+PT GE+ I G + + EN R
Sbjct: 365 LHDISFEAQPNSIIAFAGPSGGGKSTIFSLLERFYQPTAGEITIGGQPIDSVSLENWRSQ 424
Query: 415 VAYVPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ +V Q+ I +IREN+ + N T E++ + +A F+ ++P +T VGE+G
Sbjct: 425 IGFVSQDSAIMAGTIRENLTYGLEGNFTDEDLWQVLDLAFARSFVENMPDQLNTEVGERG 484
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+ +SGGQRQR+A+ARA L NPKI++LD+ ++LD+E+E + L +++ +T L+++ R
Sbjct: 485 VKISGGQRQRLAIARAFLRNPKILMLDEATASLDSESESMVQRALDSLMKGRTTLVIAHR 544
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSE 569
LS + D++ ++ G+I GK EL+ ++++
Sbjct: 545 LSTIVDADKIYFIEKGEITGSGKHNELVATHPLYAK 580
>sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN A)
>gi|283551|pir||S27337 multidrug resistance protein A -
Caenorhabditis elegans >gi|6809|emb|CAA46190.1| (X65054)
P-glycoprotein A [Caenorhabditis elegans]
Length = 1321
Score = 238 bits (602), Expect = 1e-61
Identities = 153/485 (31%), Positives = 260/485 (53%), Gaps = 9/485 (1%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLY--SIFLIIISL 152
LR + ++I R E+ +FD SG L +++ ++ ER+ ++ M S F+ +
Sbjct: 171 LRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQFITGFIV 230
Query: 153 YYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTI 212
+ +TL M+A+ I + G +M I + +R+ + TI+ I+T+
Sbjct: 231 AFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKA--GKVVEETISSIRTV 288
Query: 213 KSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQN 272
SL+ ++S EE V + A ++ + FY G +
Sbjct: 289 VSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWVHDG 348
Query: 273 TLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEI 332
+L G+++ + ++ L G + + + AAS +++V+D P ID
Sbjct: 349 SLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPV-IDSSSKAGR 407
Query: 333 SNPR--GEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARF 388
+ + G+I +V TY + V L+G++ +V G+ V + G G GKS+I+ L+ R+
Sbjct: 408 KDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRY 467
Query: 389 YKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA 448
Y KG++ IDGV+V I E LRK VA V QEP +FN +I ENI+L K T+EE+ A
Sbjct: 468 YDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITREEMVAA 527
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
K+A FI +LP GY+T+VG++G LSGGQ+QRIA+ARA++ NPKI+LLD+ S LDA
Sbjct: 528 CKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDA 587
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFS 568
E+E + + L + + +T +I++ RLS ++ D +I K+G++VE G L+ + G++
Sbjct: 588 ESEGIVQQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYY 647
Query: 569 EMMKA 573
+++ A
Sbjct: 648 DLVTA 652
Score = 226 bits (569), Expect = 7e-58
Identities = 166/584 (28%), Positives = 289/584 (49%), Gaps = 32/584 (5%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYT--------NSIVPVLIRNAIDKGVSTGAYKVA 59
L +L + R HA+ IG+ + + S + V N D +S G +
Sbjct: 740 LFEILYHARPHALSLFIGMSTATIGGFIYPTYSVFFTSFMNVFAGNPADF-LSQGHF--- 795
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSG 117
+ L+ L++ G+ S + + A++ LR FR + + FFD + SG
Sbjct: 796 --WALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASG 853
Query: 118 QLISRITNDTERITRFLSFRVRMLLYSIFLII--ISLYYMVRMNITLTMVALITIAIVVG 175
++ +R+ D + + FR ++ ++ ++ I L + + L ++A++ I + G
Sbjct: 854 KISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMALLIIAILPI-VAFG 912
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIAS--IATGTIAGIKTIKSLSVEENVQTKFSQENEELY 233
Y R ++ + S IA I ++T+++L+ E+ F ++ + +
Sbjct: 913 ---QYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDTFYENFCEKLDIPH 969
Query: 234 SLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL 293
+K I L VL L ++T Y G A+I + + L M +
Sbjct: 970 KEAIKEAFIQGLSYGCASSVLYL-LNTCAYRMGLALIITDPPTMQPMRVLRVMYAITIST 1028
Query: 294 RALGFTIG---DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY-- 348
LGF + ++ A +F ++ K A E G++ F++V Y
Sbjct: 1029 STLGFATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPE 1088
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
+LKG+SF V+PG+ + + GP G GKS+++ L+ RFY GE+ IDG + +
Sbjct: 1089 RPEIEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNP 1148
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENI--ALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
E+ R +A V QEP +F+ SI ENI L + T +VE AA++A IH+FIA LP+G++
Sbjct: 1149 EHTRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFIAELPEGFE 1208
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T VG++G LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD E+EK + E L + +T
Sbjct: 1209 TRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVVQEALDRAREGRT 1268
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++++ RL+ V D + V+ +G I+E G +L+ + G + ++
Sbjct: 1269 CIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGAYYKL 1312
>pir||T23476 hypothetical protein K08E7.9 - Caenorhabditis elegans
>gi|3878418|emb|CAB01232.1| (Z77666) Similarity to
C.elegans multidrug resistance protein (SW:MDR1_CAEEL),
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=440.3, E-value=5.6e-129, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=494.7, E-value=2.2e>
Length = 1321
Score = 238 bits (602), Expect = 1e-61
Identities = 153/485 (31%), Positives = 260/485 (53%), Gaps = 9/485 (1%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLY--SIFLIIISL 152
LR + ++I R E+ +FD SG L +++ ++ ER+ ++ M S F+ +
Sbjct: 171 LRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQFITGFIV 230
Query: 153 YYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTI 212
+ +TL M+A+ I + G +M I + +R+ + TI+ I+T+
Sbjct: 231 AFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKA--GKVVEETISSIRTV 288
Query: 213 KSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQN 272
SL+ ++S EE V + A ++ + FY G +
Sbjct: 289 VSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWVHDG 348
Query: 273 TLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEI 332
+L G+++ + ++ L G + + + AAS +++V+D P ID
Sbjct: 349 SLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPV-IDSSSKAGR 407
Query: 333 SNPR--GEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARF 388
+ + G+I +V TY + V L+G++ +V G+ V + G G GKS+I+ L+ R+
Sbjct: 408 KDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRY 467
Query: 389 YKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA 448
Y KG++ IDGV+V I E LRK VA V QEP +FN +I ENI+L K T+EE+ A
Sbjct: 468 YDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITREEMVAA 527
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
K+A FI +LP GY+T+VG++G LSGGQ+QRIA+ARA++ NPKI+LLD+ S LDA
Sbjct: 528 CKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDA 587
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFS 568
E+E + + L + + +T +I++ RLS ++ D +I K+G++VE G L+ + G++
Sbjct: 588 ESEGIVQQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYY 647
Query: 569 EMMKA 573
+++ A
Sbjct: 648 DLVTA 652
Score = 226 bits (569), Expect = 7e-58
Identities = 166/584 (28%), Positives = 289/584 (49%), Gaps = 32/584 (5%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYT--------NSIVPVLIRNAIDKGVSTGAYKVA 59
L +L + R HA+ IG+ + + S + V N D +S G +
Sbjct: 740 LFEILYHARPHALSLFIGMSTATIGGFIYPTYSVFFTSFMNVFAGNPADF-LSQGHF--- 795
Query: 60 IRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSG 117
+ L+ L++ G+ S + + A++ LR FR + + FFD + SG
Sbjct: 796 --WALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASG 853
Query: 118 QLISRITNDTERITRFLSFRVRMLLYSIFLII--ISLYYMVRMNITLTMVALITIAIVVG 175
++ +R+ D + + FR ++ ++ ++ I L + + L ++A++ I + G
Sbjct: 854 KISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMALLIIAILPI-VAFG 912
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIAS--IATGTIAGIKTIKSLSVEENVQTKFSQENEELY 233
Y R ++ + S IA I ++T+++L+ E+ F ++ + +
Sbjct: 913 ---QYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDTFYENFCEKLDIPH 969
Query: 234 SLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL 293
+K I L VL L ++T Y G A+I + + L M +
Sbjct: 970 KEAIKEAFIQGLSYGCASSVLYL-LNTCAYRMGLALIITDPPTMQPMRVLRVMYAITIST 1028
Query: 294 RALGFTIG---DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY-- 348
LGF + ++ A +F ++ K A E G++ F++V Y
Sbjct: 1029 STLGFATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPE 1088
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
+LKG+SF V+PG+ + + GP G GKS+++ L+ RFY GE+ IDG + +
Sbjct: 1089 RPEIEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNP 1148
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENI--ALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
E+ R +A V QEP +F+ SI ENI L + T +VE AA++A IH+FIA LP+G++
Sbjct: 1149 EHTRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFIAELPEGFE 1208
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T VG++G LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD E+EK + E L + +T
Sbjct: 1209 TRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVVQEALDRAREGRT 1268
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++++ RL+ V D + V+ +G I+E G +L+ + G + ++
Sbjct: 1269 CIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGAYYKL 1312
>gb|AAD53034.1|AF115537_1 (AF115537) TAP2 protein [Oncorhynchus mykiss]
Length = 713
Score = 238 bits (602), Expect = 1e-61
Identities = 158/575 (27%), Positives = 296/575 (51%), Gaps = 22/575 (3%)
Query: 7 QLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLI 66
QL+R++ Y + ++ + L + +P ID +G Y+ + +
Sbjct: 143 QLMRMVRYCKPDTLYLAAAFLFLSLAVICETFIPYYQGKVID--TLSGQYQ----HNSFM 196
Query: 67 LLVGVLNGVFSLAGRY-------LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQL 119
+G + G+ SL L + + +R F + + ++ FF++ G L
Sbjct: 197 YAIGGM-GLVSLGSALCSGLRGGLFMCSLSRLNKRMRNMLFHNLVQQDIPFFEENKPGSL 255
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+SR+ D +++ R ++ +L+ ++ L+ M+ + LT++ ++ + ++ L T
Sbjct: 256 VSRLGYDVDKMGRSVALNSNVLVRTLVKTAGILFLMLGLFWQLTLLTMVEMPLLTLLQTK 315
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
Y + +++ I +AT I ++T++S EE Q +++Q E +Y +
Sbjct: 316 YNTNNQEFIKQLQDCQAQIKELATQAIGAVRTVRSFKAEEKEQDRYNQALETMYKVQEHK 375
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFT 299
I+A++ +V M + + I L++G ++AF+ + M+ ++ L +
Sbjct: 376 GIISAVHLLLKRVVTVGLKVAMLFLCRRLISAGHLSIGSVLAFVLFQKDMVTNMKQLVYV 435
Query: 300 IGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPR--GEIEFRDVWLTYHTGRTV--L 355
GD+ ++ AA+++F +D P D +A E++ + G++ F V Y + + L
Sbjct: 436 FGDMLCTVGAAAKVFTFLDRKP---DQKEAGELAPAKLQGKLAFYHVSFYYPSRQNTPAL 492
Query: 356 KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIV 415
K VS ++ PG+ + GP G GKSS + L+AR Y+P +G+VL+DG + + + L + +
Sbjct: 493 KAVSLELHPGKMTALVGPSGGGKSSCVSLLARLYEPKEGQVLLDGQPLHCYQHQYLHQKM 552
Query: 416 AYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
A V QEP +F+ SIR NI T E+V++AAK A IHDFI +L +GYDT VGE G
Sbjct: 553 ALVSQEPVLFSGSIRHNIEYGLVGCTLEKVKKAAKSANIHDFICTLEQGYDTDVGECGGQ 612
Query: 476 LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLS 535
LS GQ+ IA+ARA++ P++++LD+ S++D T+ V+ + T L+V+ RL
Sbjct: 613 LSSGQKHCIAIARALVREPQVLILDEATSSMDINTQ-HAVQGVLAGSVGLTVLVVAHRLQ 671
Query: 536 LVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
V+ D +I M+ G++VE G +EL+ G + +
Sbjct: 672 TVEKADHIIFMEGGEVVEQGTHQELMASKGRYHRL 706
>pir||B64655 multidrug resistance protein - Helicobacter pylori (strain 26695)
>gi|2314232|gb|AAD08127.1| (AE000615) multidrug
resistance protein (msbA) [Helicobacter pylori 26695]
Length = 551
Score = 238 bits (601), Expect = 1e-61
Identities = 149/553 (26%), Positives = 291/553 (51%), Gaps = 18/553 (3%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDK-GVSTGAYKVAIRYGLLILL 68
R YL+ H F++ LF ++++ + + L++ +D+ ++ + + I L+IL
Sbjct: 7 RYSKYLKEHYKSFIVVLFSSLVVALSTAWGTYLVKPTLDEIFINKDTHMLKILPFLVILA 66
Query: 69 -VGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
+G G++ G Y V +R ++ + EM+FF++T G+LI+RITND
Sbjct: 67 YLGKSGGMY--LGTYFTNFIGLDIVKKIRNTMLESLLKMEMDFFNRTKKGELIARITNDI 124
Query: 128 ERI----TRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
I + +LS +R L + L+ + +Y + L +V L+ + + + K
Sbjct: 125 GLIRASLSNYLSESIREGLTIVGLVGVVIYQSPK----LALVGLVIMPLAAIPISKIIRK 180
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
V+ + + I + + ++ IK + E+ F +ENE + + +K + +
Sbjct: 181 VKKLAKSHQESNAKITARLSEVFNNVEAIKISNGEKLEHKAFVKENEAFFKIGIKNIAVA 240
Query: 244 ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
+ + +A++ + Y GG +I+ ++VG +F+T + + P++ L + +
Sbjct: 241 EISSPLMEFLGSIAIALVIYLGGNEVIRGHISVGAFFSFITALFMLYTPIKRLTRIVSNF 300
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY---HTGRTVLKGVSF 360
Q +L A+ R+ ++++ P +D + ++N IEF+ VWL Y + R VL +S
Sbjct: 301 QEALVASDRIHEILEREPAIVD--GELTLNNAIHTIEFKKVWLAYTLDNQERYVLNDISL 358
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
K + E + + G GSGKSS++ LI R Y+P+KGE+ I+ + I ++LR+ ++ V Q
Sbjct: 359 KFQQNEIIALKGESGSGKSSLVNLILRLYEPSKGEIFINDQKIESITQKSLREKISVVTQ 418
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
FIFN S+ EN+A + +++ K A+ DF+ +P G ++V+ E G LSGGQ
Sbjct: 419 RVFIFNGSVAENVAYGL-EIDEVKIKECLKKAQALDFVEKMPHGIESVLDEFGANLSGGQ 477
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
RQRIA+ARA+ + ++++ D+ S LD TE+ + + + E+ Q++ +++S S +KL
Sbjct: 478 RQRIAIARALYKDVQVLIFDEATSALDNNTEESVKQSILELKQNRLIILISHNPSTLKLA 537
Query: 541 DRVIVMKDGKIVE 553
+ + ++ G++ E
Sbjct: 538 TKHVKLEHGRLTE 550
>pir||DVHY2C multidrug resistance protein 2 - Chinese hamster (fragment)
>gi|387054|gb|AAA37007.1| (M17896) P-glycoprotein (pgp2)
[Cricetulus griseus]
Length = 655
Score = 238 bits (600), Expect = 2e-61
Identities = 157/526 (29%), Positives = 280/526 (52%), Gaps = 19/526 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ L L++G++ V + KA + LR F+++ R ++ +FD + +G L
Sbjct: 132 FSLFFLVMGMICFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHRNSTGAL 191
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFL----IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ +D + +S R+ + ++ IIISL Y +TL +V + + I+ G
Sbjct: 192 TTRLASDAANVKGAMSSRLAGITQNVANLGTGIIISLVY--GWQLTLLLVVIAPLIILSG 249
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + + + DK + V IAT I +T+ SL+ E+ + ++Q + Y
Sbjct: 250 MMEMKVLSGQALKDK--KELEVSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRN 307
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGE-LVAFLTYMLTMMWPLR 294
+K + + + ++ + + F +G + +T ++ F + +
Sbjct: 308 ALKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAHQIMTFENVMLVFSAVVFGAIAAGN 367
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP--RGEIEFRDVWLTYHTGR 352
A F D ++ +AS + +++ P SID + G ++F +V Y T
Sbjct: 368 ASSFA-PDYAKAKVSASHIIRIMEKIP-SIDSYSTRGLKPNWLEGNVKFNEVVFNYPTRP 425
Query: 353 T--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTEN 410
VL+G+S +VK G+ + + G G GKS++++L+ RFY P G V +DG + ++ +
Sbjct: 426 DIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQW 485
Query: 411 LRKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLPKGYDTV 468
LR + V QEP +F+ SI ENIA + +Q+E+ERAAK A IH FI SLP Y+T
Sbjct: 486 LRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTR 545
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
VG+KG LSGGQ+QRIA+ARA++ P I+LLD+ S LD E+EK + E L + + +T +
Sbjct: 546 VGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCI 605
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
+++ RLS ++ D ++V+++GK+ E G ++L+ + GI+ M++AG
Sbjct: 606 VIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVQAG 651
>gb|AAB51079.1| (L40491) leucocin A translocator [Leuconostoc gelidum]
Length = 717
Score = 237 bits (598), Expect = 3e-61
Identities = 171/577 (29%), Positives = 302/577 (51%), Gaps = 21/577 (3%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
++S+ I +++ + ++ +I L+ L+S S ++ ID +
Sbjct: 151 KRSLTSFIPVITRQKLLVINIVIAALLVTLVSILGSYY---LQGIIDTYIPDNMKNTLGI 207
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
L ++ V+ + S A YLL+ Q + + + I M FF +G+++S
Sbjct: 208 VSLGLIFAYVIQQLLSYARDYLLIVMGQRLSIDIILSYIKHIFELPMSFFATRRTGEIVS 267
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITI---AIVVGLNT 178
R T+ I S + + L L+I+ +V+ N TL +++LI I A+VV L
Sbjct: 268 RFTDANAIIEALASTMLSVFLDLGILVIVGTVLVVQ-NSTLFLISLIAIPAYALVVWLFM 326
Query: 179 TYAMKVRPIYDKIRHQTG-VIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
K+ + + Q G +++S I G++TIK+L+ EE K E +
Sbjct: 327 RPFSKM----NNDQMQAGSMLSSSIIEDINGVETIKALNSEETAYHKIDHEFVTYLEKSF 382
Query: 238 KAMKITALYGNAPFLVLGLAMSTMFYY-GGKAIIQNTLTVGELVAFLTYMLTMMWPLRAL 296
K A NA +L L+++ + + G + ++ N ++VG+L+ + + PL+ +
Sbjct: 383 VYAKTEATQ-NAIKSLLQLSLNVVILWVGAQLVMTNKISVGQLITYNALLGFFTDPLQNI 441
Query: 297 GFTIGDIQRSLAAASRLFDV--IDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+Q++ A +RL +V +DS K+ E P + + Y G
Sbjct: 442 INLQTKLQQASVANNRLNEVYLVDSEFKASH--QMTESIMPNSSLVADHITYKYGFGAPA 499
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
+ VS + GEK+ + G GSGKS+++KL+ F++P G + + +A + LR
Sbjct: 500 IDDVSLTITAGEKIALVGISGSGKSTLVKLLVNFFQPESGTISLGQTPLANLDKHELRAH 559
Query: 415 VAYVPQEPFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ Y+PQEPFIF+ SI +N+ L AKP TQE++ RA +IA+I D I + +G+ T + E G
Sbjct: 560 INYLPQEPFIFSGSIMDNLLLGAKPGTTQEDIIRAVEIAEIKDDIEKMSQGFGTELAESG 619
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+SGGQ+QRIALARA+L++ +++LD+ SNLD TEKK++++L + L +KT + V+ R
Sbjct: 620 -NISGGQKQRIALARAILVDSPVLILDESTSNLDVLTEKKIIDNLMQ-LTEKTIIFVAHR 677
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
L++ + VDR++ M++GKI+EDG L+ GG ++ +
Sbjct: 678 LTISQRVDRILTMQNGKIIEDGTHNTLLNAGGFYASL 714
>sp|P18767|NDVA_RHIME BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTEIN NDVA
>gi|72495|pir||VXZRNA beta-1,2-glucan export protein
ndvA - Rhizobium meliloti >gi|152269|gb|AAA26304.1|
(M20726) ndvA peptide (put.); putative [Sinorhizobium
meliloti]
Length = 616
Score = 236 bits (597), Expect = 4e-61
Identities = 162/573 (28%), Positives = 286/573 (49%), Gaps = 15/573 (2%)
Query: 10 RLLSYLRGHAVHFLIGLFLI--ILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
R L YL H F +G +I I+++ P+L ID + VA +L+L
Sbjct: 40 RALQYLAVHK--FRVGAIVIANIVLAAITIAEPILFGRIID--AISSQKDVA---PMLLL 92
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRM----DAFRAIQRHEMEFFDKTFSGQLISRI 123
G GVF+ L+ + A + R +AF I + + + + + +
Sbjct: 93 WAGF--GVFNTIAFVLVSREADRLAHGRRASLLTEAFGRIVSMPLSWHSQRGTSNALHTL 150
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
E + +R L + +++ + M++ L+++ ++ A V ++ +
Sbjct: 151 LRACETLFGLWLEFMRQHLATAVALMLLIPTAFAMDVRLSLILVVLGAAYVMISKVVMSR 210
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT 243
+ + + S + +I+ + + S + E + + + L S +
Sbjct: 211 TKEGQAAVEGHYHTVFSHVSDSISNVSVVHSYNRIEAETRELKKFTQRLLSAQYPVLDWW 270
Query: 244 ALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
AL + ++M + G + + L VGE++AF+ + ++ L + I
Sbjct: 271 ALASGLNRIASTISMMAILVIGTVLVQRGELGVGEVIAFIGFANLLIGRLDQMKAFATQI 330
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVK 363
+ A F + DS +P DA E+ GE+EFRD+ + ++ VSFK K
Sbjct: 331 FEARAKLEDFFQLEDSVQDREEPADAGELKGVVGEVEFRDISFDFANSAQGVRNVSFKAK 390
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
G+ + I GP G+GK++++ L+ R ++P G++LIDGV++A + ++LR+ +A V Q+
Sbjct: 391 AGQTIAIVGPTGAGKTTLVNLLQRVHEPKHGQILIDGVDIATVTRKSLRRSIATVFQDAG 450
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+ NRSI ENI L + +A+ +EV AA+ A DFI GYDTVVGE+G LSGG+RQR
Sbjct: 451 LMNRSIGENIRLGREDASLDEVMAAAEAAAASDFIEDRLNGYDTVVGERGNRLSGGERQR 510
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
+A+ARA+L N I++LD+ S LD ETE ++ + + + +D+T I++ RLS V+ D V
Sbjct: 511 VAIARAILKNAPILVLDEATSALDVETEARVKDAIDALRKDRTTFIIAHRLSTVREADLV 570
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
I M G++VE G EL + G F+ +++A G+
Sbjct: 571 IFMDQGRVVEMGGFHELSQSNGRFAALLRASGI 603
>gb|AAG01549.1|AF291822_1 (AF291822) multidrug resistance protein MDR [Trichophyton rubrum]
Length = 1217
Score = 236 bits (596), Expect = 5e-61
Identities = 164/590 (27%), Positives = 299/590 (49%), Gaps = 31/590 (5%)
Query: 4 SINQLIRLLS-YLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR- 61
S+ LIR ++ + + + L G F +L + V KG++T + ++
Sbjct: 628 SLGTLIRFIAGFNKPERLIMLCGFFFAVLSGAGQPVQSVFFA----KGITTLSLPPSLYG 683
Query: 62 --------YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD- 112
+ L+ L++G++ V A + ++ +Y R +FRA+ R ++ FFD
Sbjct: 684 KLREDANFWSLMFLMLGLVQLVTQSAQGVIFAICSESLIYRARSKSFRAMLRQDIAFFDL 743
Query: 113 -KTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIA 171
+ +G L S ++ +T+ ++ + +L +I++L + L +V + T+
Sbjct: 744 PENSTGALTSFLSTETKHLSGVSGATLGTILMVSTTLIVALTVALAFGWKLALVCISTVP 803
Query: 172 IVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEE 231
+++ + + + AS A + I+T+ SL+ E+ V + + +
Sbjct: 804 VLLLCGFYRFWILAQFQTRAKKAYESSASYACEATSSIRTVASLTREQGVMEIYEGQLND 863
Query: 232 LYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLT--M 289
+++++ ++L A ++ F+YGG L GE AF ++ +
Sbjct: 864 QAKKSLRSVAKSSLLYAASQSFSFFCLALGFWYGG-----GLLGKGEYNAFQFFLCISCV 918
Query: 290 MWPLRALGFTIG---DIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVW 345
++ ++ G D+ ++ +AA+ + D P I+ D ++ G IEFRDV
Sbjct: 919 IFGSQSAGIVFSFSPDMGKAKSAAADFKRLFDRVPTIDIESTDGEKLETVEGTIEFRDVH 978
Query: 346 LTYHTG--RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNV 403
Y T + VL+G++ VKPG+ + + GP G GKS+ + L+ RFY G V IDG ++
Sbjct: 979 FRYPTRPEQPVLRGLNLTVKPGQYIALVGPSGCGKSTTIALVERFYDTLSGGVYIDGKDI 1038
Query: 404 AKIKTENLRKIVAYVPQEPFIFNRSIRENIALA--KPNATQEEVERAAKIAKIHDFIASL 461
+++ + R +A V QEP ++ +IR+N+ L + + E+V A K A I+DFI SL
Sbjct: 1039 SRLNVNSYRSHLALVSQEPTLYQGTIRDNVLLGVDRDDVPDEQVFAACKAANIYDFIMSL 1098
Query: 462 PKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI 521
P G+ TVVG KG LSGGQ+QRIA+ARA++ +PK++LLD+ S LD+E+EK + L
Sbjct: 1099 PDGFGTVVGSKGSMLSGGQKQRIAIARALIRDPKVLLLDEATSALDSESEKVVQAALDAA 1158
Query: 522 LQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
+ +T + V+ RLS ++ D + V G+IVE G EL++ G + E++
Sbjct: 1159 AKGRTTIAVAHRLSTIQKADIIYVFDQGRIVESGTHHELLQNKGRYYELV 1208
Score = 220 bits (554), Expect = 4e-56
Identities = 155/544 (28%), Positives = 279/544 (50%), Gaps = 44/544 (8%)
Query: 58 VAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSG 117
+ R L + +G+ + + ++ +R AI R + FFDK +G
Sbjct: 26 ILTRNSLYFVYLGIAQFILLYVSTVGFIYVGEHITQKIRAKYLHAILRQNIGFFDKLGAG 85
Query: 118 QLISRITNDTERITRFLSFRVRMLL------YSIFLIIISLYYMVRMNITLTMVALITIA 171
++ +RIT DT I +S +V + L +S F+I Y+ + + + T+VA+I
Sbjct: 86 EVTTRITADTNLIQDGISEKVGLTLTALSTFFSAFIIGYVRYWKLALICSSTIVAMI--- 142
Query: 172 IVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEE 231
+V+G + + +K + + + G ++A I+ I+ + +E + ++ +E
Sbjct: 143 LVMGGISRFVVKSGRM-TLVSYGEG--GTVAEEVISSIRNATAFGTQEKLARQYEVHLKE 199
Query: 232 LYSLNVKA-MKITALYGNAPFLV-----LGLAMSTMFYYGGKAIIQNTLTVGELVAFLTY 285
+ M + ++G+ ++ LG M + F GG+ +L A +
Sbjct: 200 ARKWGRRLQMMLGIMFGSMMAIMYSNYGLGFWMGSRFLVGGET---------DLSAIVNI 250
Query: 286 MLTMMWPLRALGFTIGDIQR---SLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIE 340
+L ++ ++G + Q +++A +++F ID +IDP + I N G IE
Sbjct: 251 LLAIVIGSFSIGNVAPNTQAFASAISAGAKIFSTIDRV-SAIDPGSDEGDTIENVEGTIE 309
Query: 341 FRDVWLTYHTGR--TVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLI 398
FR + Y + V++ ++ V G+ + GP GSGKS+++ L+ RFY P G VL+
Sbjct: 310 FRGIKHIYPSRPEVVVMEDINLVVPKGKTTALVGPSGSGKSTVVGLLERFYNPVSGSVLL 369
Query: 399 DGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-----KPNATQEEVER----AA 449
DG ++ + LR+ ++ V QEP +F +I ENI L N ++E+++ AA
Sbjct: 370 DGRDIKTLNLRWLRQQISLVSQEPTLFGTTIFENIRLGLIGSPMENESEEQIKERIVSAA 429
Query: 450 KIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAE 509
K A HDFI LP GY T VG++G LSGGQ+QRIA+ARA++ +PKI+LLD+ S LD +
Sbjct: 430 KEANAHDFIMGLPDGYATDVGQRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSALDTK 489
Query: 510 TEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSE 569
+E + L + +T ++++ RLS +K D ++V+ G+I E G +EL+ K G + +
Sbjct: 490 SEGVVQAALDAASRGRTTIVIAHRLSTIKSADNIVVIVGGRIAEQGTHDELVDKKGTYLQ 549
Query: 570 MMKA 573
+++A
Sbjct: 550 LVEA 553
>sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-GLYCOPROTEIN 65)
>gi|103252|pir||B41249 multidrug resistance protein
homolog Mdr65 - fruit fly (Drosophila melanogaster)
>gi|157875|gb|AAA28680.1| (M59077) P-glycoprotein
[Drosophila melanogaster]
Length = 1302
Score = 235 bits (593), Expect = 1e-60
Identities = 161/551 (29%), Positives = 291/551 (52%), Gaps = 24/551 (4%)
Query: 43 IRNAIDKGVSTGAYKVAIRYGLLILLVGV---LNGVFSLAGRYLLVKAAQYAVYYLRMDA 99
+ NA + + Y +I YG+L+ + V ++G+FS+ + A V +R+
Sbjct: 101 LTNASREENNEALYDDSISYGILLTIASVVMFISGIFSVD---VFNMVALRQVTRMRIKL 157
Query: 100 FRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMN 159
F ++ R ++ + D + +D E+I +S +V +Y + II++
Sbjct: 158 FSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYG 217
Query: 160 ITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEE 219
LT+ I +V+ LN A + + + ++A ++ I+T+ S E+
Sbjct: 218 WKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEK 277
Query: 220 NVQTKFSQENEELYSLNVKAMK--ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVG 277
+ ++ EN + + K + L +L L+ + F+YG II +
Sbjct: 278 SEVQRY--ENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVEN 335
Query: 278 E-------LVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PD 328
+ ++AF ++ R F + + A+ LF VID K IDP D
Sbjct: 336 KEYTPAILMIAFFGIIVGADNIARTAPF-LESFASARGCATNLFKVIDLTSK-IDPLSTD 393
Query: 329 AVEIS-NPRGEIEFRDVWLTYHTGRTVL--KGVSFKVKPGEKVLITGPPGSGKSSILKLI 385
++ RG++EF+DV+ Y + V+ +G++ +++ G+ V + G G GKS+ ++L+
Sbjct: 394 GKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLL 453
Query: 386 ARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEV 445
RFY P G VL+D +++ K + LR +A V QEP +F +I +NI+ KP ATQ+E+
Sbjct: 454 QRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEI 513
Query: 446 ERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSN 505
E AA A H+FI +LP+ Y +++GE+G LSGGQ+QRIA+ARA++ NPKI+LLD+ S
Sbjct: 514 EAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSA 573
Query: 506 LDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGG 565
LD ++EK++ + L + +T ++VS RLS ++ D+++ + DGK++E+G ++L+ G
Sbjct: 574 LDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEG 633
Query: 566 IFSEMMKAGGV 576
+ M++AG +
Sbjct: 634 AYYNMVRAGDI 644
Score = 213 bits (537), Expect = 4e-54
Identities = 148/517 (28%), Positives = 265/517 (50%), Gaps = 20/517 (3%)
Query: 72 LNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS--GQLISRITNDTER 129
L G+ YL A + +R F A+ E+ +FD + G L +R++ +
Sbjct: 785 LTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGEAVD 844
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
I + + + ++ ++ I S+ + N L ++ L I+VG + ++ + + +
Sbjct: 845 IQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVG---SVILEAKMMSN 901
Query: 190 KIRHQTGVIAS---IATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALY 246
+ + VI IAT +I I+T+ L E +V ++++E + + L + ++ +
Sbjct: 902 AVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQKLRWRGVL 961
Query: 247 GNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFL-TYMLTMMWPLRALGFTIGDIQR 305
+ A + YGG + + L +++ T + M ++L FT
Sbjct: 962 NSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPA-FSA 1020
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEIS-----NPRGEIEFRDVWLTYHT--GRTVLKGV 358
+L A RLF ++D PK P ++ + N + +R + Y T +L G+
Sbjct: 1021 ALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRPDAKILNGL 1080
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT-ENLRKIVAY 417
+V G+ V + G G GKS+ ++L+ R+Y P +G + ID ++ T + +R +
Sbjct: 1081 DLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKLGI 1140
Query: 418 VPQEPFIFNRSIRENIALA--KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
V QEP +F RSI ENIA + + + E+ AAK A H FI SLP GYDT +G +G
Sbjct: 1141 VSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQ 1200
Query: 476 LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLS 535
LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD ++E+ + + L +T ++++ RLS
Sbjct: 1201 LSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLS 1260
Query: 536 LVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
V+ D + V+++G++VE G +LI +GGI++++ K
Sbjct: 1261 TVQNADVICVIQNGQVVEQGNHMQLISQGGIYAKLHK 1297
>gb|AAB88657.1| (U62933) multidrug resistance protein 1 [Aspergillus fumigatus]
>gi|2673953|gb|AAB88658.1| (U62934) multidrug resistance
protein 1 [Aspergillus fumigatus]
Length = 1349
Score = 235 bits (593), Expect = 1e-60
Identities = 167/597 (27%), Positives = 296/597 (48%), Gaps = 44/597 (7%)
Query: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGA------ 55
RK I LI L+S + A + LF I+ S ++ +G+S G
Sbjct: 105 RKDI--LIILVSAICAIAAGAALPLFTILFGSLASAF----------QGISLGTMPYHEF 152
Query: 56 YKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTF 115
Y + L + +G+ V + ++ +R + AI R M +FDK
Sbjct: 153 YHKLTKNVLYFVYLGIAEFVTVYVSTVGFIYTGEHLTQKIRENYLEAILRQNMAYFDKLG 212
Query: 116 SGQLISRITNDTERITRFLSFRVRMLLYSI------FLIIISLYYMVRMNITLTMVALIT 169
+G++ +RIT DT I +S +V + L + F++ Y+ + + T T+VAL+
Sbjct: 213 AGEVTTRITADTNLIQDAISEKVGLTLTAFATFVTAFIVAYVKYWKLALICTSTIVALV- 271
Query: 170 IAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQEN 229
+V+G + + +K K G ++A I+ I+ + ++ + ++
Sbjct: 272 --MVMGGGSRFIVKYSK---KSIESYGAGGTVAEEVISSIRNATAFGTQDKLAKQYETHL 326
Query: 230 EELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTM 289
E VK I + F ++ F+ G + ++ + VG+++ L +L
Sbjct: 327 AEAEKWGVKQQVILGMMIGGMFGIMFSNYGLGFWMGSRFVVGKEVNVGQVLTVLMSILIG 386
Query: 290 MWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLT 347
+ L + +AAA++++ ID +DP + + + G IEFR+V
Sbjct: 387 SFSLGNVAPNGQAFTNGVAAAAKIYSTIDRR-SPLDPYSDEGKVLDHFEGNIEFRNVKHI 445
Query: 348 YHTGR--TVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAK 405
Y + TV++ VS + G+ + GP GSGKS+++ L+ RFY P G+VL+DG ++
Sbjct: 446 YPSRPEVTVMEDVSLSMPAGKTTALVGPSGSGKSTVVGLVERFYLPVGGQVLLDGHDIQT 505
Query: 406 IKTENLRKIVAYVPQEPFIFNRSIRENIALA---------KPNATQEEVERAAKIAKIHD 456
+ LR+ ++ V QEP +F+ +I NI + +E VE AA++A HD
Sbjct: 506 LNLRWLRQQISLVSQEPVLFSTTIFRNIEHGLIGTKFEHESKDKIRELVENAARMANAHD 565
Query: 457 FIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVE 516
FI +LP+GYDT VG++G LSGGQ+QRIA+ARA++ +PKI+LLD+ S LD ++E +
Sbjct: 566 FIMALPEGYDTNVGQRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSALDTKSEGVVQA 625
Query: 517 DLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
L + + +T ++++ RLS +K ++ M GKI E G +EL+ + G + ++++A
Sbjct: 626 ALDKAAEGRTTIVIAHRLSTIKTAHNIVAMVGGKIAEQGTHDELVDRKGTYYKLVEA 682
Score = 233 bits (587), Expect = 6e-60
Identities = 146/518 (28%), Positives = 271/518 (52%), Gaps = 9/518 (1%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK--TFSGQL 119
+ L+ +VG+ + ++ + R AFR+I R ++ FFD+ +G L
Sbjct: 824 WSLMFFVVGIAQFISLSINGTAFAICSERLIRRARSQAFRSILRQDISFFDREENSTGAL 883
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
S ++ +T+ ++ + ++ + + ++ + + L +V + + I++
Sbjct: 884 TSFLSTETKNLSGVSGVTLGTIIMTSTTLGAAMIIALAIGWKLALVCISVVPILLACGFL 943
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLN-VK 238
+ + + AS A + I+T+ SL+ E++V + + ++ + +
Sbjct: 944 RFYMLAQFQQRSKSAYEGSASYACEATSAIRTVASLTREQDVWGVYHDQLQKQGRKSLIS 1003
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGF 298
++ + LY ++ LV ++ F+YGG + + ++ + +L +
Sbjct: 1004 VLRSSLLYASSQALVF-FCVALGFWYGGTLLGHHEYSIFRFFVCFSEILFGAQSAGTVFS 1062
Query: 299 TIGDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVL 355
D+ ++ AA++ + DS P I + ++ + GEIEFRDV Y T + VL
Sbjct: 1063 FAPDMGKAKNAAAQFKKLFDSKPTIDIWSDEGEKLESMEGEIEFRDVHFRYPTRPEQPVL 1122
Query: 356 KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIV 415
+G++ VKPG+ + + GP G GKS+ + L+ RFY G V +DG ++ K+ + R +
Sbjct: 1123 RGLNLSVKPGQYIALVGPSGCGKSTTIALLERFYDALAGGVFVDGKDITKLNVNSYRSFL 1182
Query: 416 AYVPQEPFIFNRSIRENIALA--KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ V QEP ++ +I+ENI L K + ++E + + K A I+DF+ SLP+G+DTVVG KG
Sbjct: 1183 SLVSQEPTLYQGTIKENILLGVDKDDVSEETLIKVCKDANIYDFVMSLPEGFDTVVGSKG 1242
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
LSGGQ+QR+A+ARA+L +PK++LLD+ S LD+E+EK + L + +T + V+ R
Sbjct: 1243 GMLSGGQKQRVAIARALLRDPKVLLLDEATSALDSESEKVVQAALDAAARGRTTIAVAHR 1302
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
LS ++ D + V GKIVE G ELI+ G + E++
Sbjct: 1303 LSTIQNADIIYVFDQGKIVESGTHHELIRNKGRYYELV 1340
>pir||T21269 hypothetical protein F22E10.4 - Caenorhabditis elegans
>gi|3876294|emb|CAA91802.1| (Z67882) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=440.3,
E-value=5.4e-129, N=2; PF00664 (ABC transporter
transmembrane region.), Score=190.4, E-value=9.4e-54,
N=1 [Caenorhabditis elegans]
Length = 1270
Score = 235 bits (593), Expect = 1e-60
Identities = 136/477 (28%), Positives = 250/477 (51%), Gaps = 6/477 (1%)
Query: 102 AIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNIT 161
++ R +FDK SG + +++ + ERI + ++ +LL + +++ S+
Sbjct: 184 SVLRQNAGWFDKHHSGTIATKLNDSMERIREGIGDKLGVLLRGVAMLVASVVVAYIYEWR 243
Query: 162 LTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENV 221
L + L +G + A ++ K SIA ++ G++T+++ + +E +
Sbjct: 244 LACMLLGVAPTCIGCMSLMARQMTATTVKELGGVEKAGSIAEESLMGVRTVQAFNGQEEM 303
Query: 222 QTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTL-TVGELV 280
++ E + + + L+G F L F YG + + + G++
Sbjct: 304 VERYRVELNKGRKFAIWKGFWSGLFGGMFFFWLFAFQGCGFLYGAYLLSVGIIKSPGDVF 363
Query: 281 AFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGE 338
+ ML + + + + + AA +++ ID PK IDP + G
Sbjct: 364 IIVMAMLLGSYFTGLISPHLMVLLNARVAAGSIYETIDRVPK-IDPYSKKGKFLDKVIGR 422
Query: 339 IEFRDVWLTYHTGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEV 396
++F +V Y T + +L G++ ++PG V + G G GKS+ + L+ R Y+P G V
Sbjct: 423 VKFENVHFRYPTRKDAKILNGLNLTIEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAGNV 482
Query: 397 LIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHD 456
IDG +V ++ + LR ++ V QEP +FN +I N+ L PNAT+E++ K+A HD
Sbjct: 483 TIDGTDVRELNIDYLRNVIGIVQQEPILFNDTIHNNLLLGNPNATREKMIEVCKMANAHD 542
Query: 457 FIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVE 516
FI +PKGYDT++G+ G+ LSGGQ+QR+A+AR ++ PK++LLD+ S LDA++E +
Sbjct: 543 FIEKMPKGYDTMIGDGGVQLSGGQKQRVAIARTLVREPKVLLLDEATSALDAQSESIVQS 602
Query: 517 DLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
L + +T ++++ RLS ++ D+++ + G IVE G EEL++ GG + +++KA
Sbjct: 603 ALNNASKGRTTIMIAHRLSTIREADKIVFFEKGVIVEAGNHEELVRLGGRYYDLVKA 659
Score = 184 bits (462), Expect = 3e-45
Identities = 116/362 (32%), Positives = 204/362 (56%), Gaps = 28/362 (7%)
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLV-----LGLAMSTMFYYGGKA---IIQNTL 274
T+F + EL ++A+ T +++ LG+ + Y+G K+ + Q +
Sbjct: 919 TRFYNKRSELKKGLIEAINYTITQSFMYYMMCFCFALGIRL---IYHGNKSPQDVFQGNI 975
Query: 275 TVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISN 334
+ +LT M + A + + ++ AA LF++I P++ D +E S
Sbjct: 976 AM---------LLTAMGVMNAAQY-FPEFVKAKTAAGLLFNIIYRKPRT---GDLLEGSR 1022
Query: 335 P--RGEIEFRDVWLTY--HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYK 390
P RG I F +V +Y + ++KG+ + G+ V + GP GSGKS+ + ++ RFY
Sbjct: 1023 PEVRGNILFENVKFSYPQRPHQPIMKGLQWTALRGQTVALVGPSGSGKSTCIGMLERFYD 1082
Query: 391 PTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAK 450
T G + IDG ++ + +LR +A V QEP +F +I+ENI L N E++ A +
Sbjct: 1083 VTGGTLRIDGQDIRGLSLFHLRTQMALVGQEPRLFAGTIKENICLGLENVPMEKINHALE 1142
Query: 451 IAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAET 510
+A + F+A+LP G +T VGEKG LSGGQ+QRIA+ARA++ +PKI+LLD+ S LD+E+
Sbjct: 1143 LANANRFLANLPAGIETDVGEKGSKLSGGQKQRIAIARALVRDPKILLLDEATSALDSES 1202
Query: 511 EKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
E+ + E L + +T + ++ RLS ++ D ++ +++G++ E G ++L+ K G + E+
Sbjct: 1203 ERAVQEALDRAREGRTCITIAHRLSSIQNSDVIVYIENGRVQEAGNHKQLMSKKGKYYEL 1262
Query: 571 MK 572
++
Sbjct: 1263 IQ 1264
>gb|AAF50669.1| (AE003563) Mdr65 gene product [Drosophila melanogaster]
>gi|7767568|gb|AAF69146.1|AF251286_1 (AF251286)
P-glycoprotein [Drosophila melanogaster]
>gi|7767570|gb|AAF69147.1|AF251287_1 (AF251287)
P-glycoprotein [Drosophila melanogaster]
Length = 1302
Score = 235 bits (593), Expect = 1e-60
Identities = 161/551 (29%), Positives = 291/551 (52%), Gaps = 24/551 (4%)
Query: 43 IRNAIDKGVSTGAYKVAIRYGLLILLVGV---LNGVFSLAGRYLLVKAAQYAVYYLRMDA 99
+ NA + + Y +I YG+L+ + V ++G+FS+ + A V +R+
Sbjct: 101 LTNASREENNEALYDDSISYGILLTIASVVMFISGIFSVD---VFNMVALRQVTRMRIKL 157
Query: 100 FRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMN 159
F ++ R ++ + D + +D E+I +S +V +Y + II++
Sbjct: 158 FSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYG 217
Query: 160 ITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEE 219
LT+ I +V+ LN A + + + ++A ++ I+T+ S E+
Sbjct: 218 WKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEK 277
Query: 220 NVQTKFSQENEELYSLNVKAMK--ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVG 277
+ ++ EN + + K + L +L L+ + F+YG II +
Sbjct: 278 SEVQRY--ENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVEN 335
Query: 278 E-------LVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PD 328
+ ++AF ++ R F + + A+ LF VID K IDP D
Sbjct: 336 KEYTPAILMIAFFGIIVGADNIARTAPF-LESFATARGCATNLFKVIDLTSK-IDPLSTD 393
Query: 329 AVEIS-NPRGEIEFRDVWLTYHTGRTVL--KGVSFKVKPGEKVLITGPPGSGKSSILKLI 385
++ RG++EF+DV+ Y + V+ +G++ +++ G+ V + G G GKS+ ++L+
Sbjct: 394 GKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLL 453
Query: 386 ARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEV 445
RFY P G VL+D +++ K + LR +A V QEP +F +I +NI+ KP ATQ+E+
Sbjct: 454 QRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEI 513
Query: 446 ERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSN 505
E AA A H+FI +LP+ Y +++GE+G LSGGQ+QRIA+ARA++ NPKI+LLD+ S
Sbjct: 514 EAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSA 573
Query: 506 LDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGG 565
LD ++EK++ + L + +T ++VS RLS ++ D+++ + DGK++E+G ++L+ G
Sbjct: 574 LDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEG 633
Query: 566 IFSEMMKAGGV 576
+ M++AG +
Sbjct: 634 AYYNMVRAGDI 644
Score = 213 bits (537), Expect = 4e-54
Identities = 148/517 (28%), Positives = 265/517 (50%), Gaps = 20/517 (3%)
Query: 72 LNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS--GQLISRITNDTER 129
L G+ YL A + +R F A+ E+ +FD + G L +R++ +
Sbjct: 785 LTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGEAVD 844
Query: 130 ITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYD 189
I + + + ++ ++ I S+ + N L ++ L I+VG + ++ + + +
Sbjct: 845 IQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVG---SVILEAKMMSN 901
Query: 190 KIRHQTGVIAS---IATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALY 246
+ + VI IAT +I I+T+ L E +V ++++E + + L + ++ +
Sbjct: 902 AVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQKLRWRGVL 961
Query: 247 GNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFL-TYMLTMMWPLRALGFTIGDIQR 305
+ A + YGG + + L +++ T + M ++L FT
Sbjct: 962 NSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPA-FSA 1020
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEIS-----NPRGEIEFRDVWLTYHT--GRTVLKGV 358
+L A RLF ++D PK P ++ + N + +R + Y T +L G+
Sbjct: 1021 ALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRPDAKILNGL 1080
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT-ENLRKIVAY 417
+V G+ V + G G GKS+ ++L+ R+Y P +G + ID ++ T + +R +
Sbjct: 1081 DLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKLGI 1140
Query: 418 VPQEPFIFNRSIRENIALA--KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
V QEP +F RSI ENIA + + + E+ AAK A H FI SLP GYDT +G +G
Sbjct: 1141 VSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQ 1200
Query: 476 LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLS 535
LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD ++E+ + + L +T ++++ RLS
Sbjct: 1201 LSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLS 1260
Query: 536 LVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
V+ D + V+++G++VE G +LI +GGI++++ K
Sbjct: 1261 TVQNADVICVIQNGQVVEQGNHMQLISQGGIYAKLHK 1297
>pir||T22090 hypothetical protein F42E11.1 - Caenorhabditis elegans
>gi|3877005|emb|CAA91463.1| (Z66562) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=429.3,
E-value=1.1e-125, N=2; PF00664 (ABC transporter
transmembrane region.), Score=422.1, E-value=1.7e-123,
N=2~cDNA EST yk375e1.5 comes from this gene~cDNA EST
yk422e5.3 c>
Length = 1266
Score = 235 bits (592), Expect = 1e-60
Identities = 143/515 (27%), Positives = 258/515 (49%), Gaps = 3/515 (0%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
Y LL L+GVL + L A+ +Y +R +++ R + ++FD+ G L
Sbjct: 96 YCLLYFLLGVLMFTCTYFSNACLFTMAERRLYCIRKHLLQSVLRQDAKWFDENTVGGLTQ 155
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
++++ E+I + ++ +L+ I I + M LT+V L+T+ + +G A
Sbjct: 156 KMSSGIEKIKDGIGDKIGVLVSGIATFISGVALGFYMCWQLTLVMLVTVPLQLGSMYLSA 215
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ +A IAGI+T+ + + + ++ + + + ++
Sbjct: 216 KHLNRATKNEMSAYSSAGGMANEVIAGIRTVIAFNAQPFEIERYGAQLAKARKMGIRKAI 275
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
+ AL P ++ + M+ F+YG T G ++ L +G
Sbjct: 276 VLALCSAMPLFLMFVLMAGAFWYGAILTSYGVATSGTTFGVFWAVILGTRRLGEAAPHMG 335
Query: 302 DIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGV 358
I + A + +F VID P+ + + G++ F ++ TY T V LKGV
Sbjct: 336 AITGARLAVNDIFKVIDHEPEINCTKQEGRRPDKVNGKLVFDNIQFTYPTRPDVKILKGV 395
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
SF+V PGE + + G G GKS+ + L+ RFY G + +DG+ + + LR + V
Sbjct: 396 SFEVNPGETIALVGHSGCGKSTSIGLLMRFYNQCAGSIKLDGIPIEDYNIQWLRSTIGIV 455
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
QEP IF ++ EN+ + + T +++E A + A HDFI L +GY+TV+G + LSG
Sbjct: 456 QQEPIIFLATVAENVRMGDDSITDKDIENACRQANAHDFIGKLSEGYNTVIGAGAVQLSG 515
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVK 538
GQ+QR+A+ARA++ P+I+LLD+ S LD E+E+ + L + + +T L ++ RLS ++
Sbjct: 516 GQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQTALDKASEGRTTLCIAHRLSTIR 575
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+++V G I E G ++LI++ GI++ M++A
Sbjct: 576 NASKILVFDQGLIPERGIHDQLIRQNGIYANMVRA 610
Score = 231 bits (583), Expect = 2e-59
Identities = 158/524 (30%), Positives = 272/524 (51%), Gaps = 16/524 (3%)
Query: 59 AIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFS 116
A+ L +L+ V + V + LL K + LRMD F+ I + + +FD K
Sbjct: 745 ALISSLWFVLLAVTSAVTTFISGSLLGKTGETMSSRLRMDVFKNIMQQDATYFDDPKHNV 804
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGL 176
G L SR+ D++ + + R+ +L + + + ++ + LIT ++V
Sbjct: 805 GNLTSRLATDSQNVQAAIDHRLAEVLNGVVSLFTGIAVAFWFGWSMAPIGLITALLLVIA 864
Query: 177 NTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEE----L 232
+ A ++ K + I T +I+ KT+++L+ +E + F+ ++
Sbjct: 865 QSAVAQYLKYRGPKDMESAIEASRIVTESISNWKTVQALTKQEYMFHAFTAASKNPRKRA 924
Query: 233 YSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTM--M 290
++ + AL G+ F + A++ MF G +I N T V + L M M
Sbjct: 925 FTKGLWQSLSFALAGS--FFLWNFAIAYMF---GLWLISNNWTTPFAVFQVIEALNMASM 979
Query: 291 WPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY-- 348
+ A + + R+ +A +F +I K + E + RG+I + V+ Y
Sbjct: 980 SVMMAASY-FPEYVRARISAGIMFTMIRQKAKIDNRGLTGETPDIRGDISMKGVYFAYPN 1038
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
+ +L + + GE V + GP G GKS+ ++LI R+Y G V ID ++ I
Sbjct: 1039 RNRQLILNNFNMSAQFGETVALVGPSGCGKSTSIQLIERYYDAICGAVKIDDHDIRDISV 1098
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTV 468
++LR +A V QEP +FN +IRENI N +QE+VE+AA +A IH F+ +LP+GYDT
Sbjct: 1099 KHLRHNIALVGQEPTLFNLTIRENITYGLENVSQEQVEKAATLANIHSFVENLPEGYDTS 1158
Query: 469 VGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTAL 528
VG G LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD E+EK + E L + +T +
Sbjct: 1159 VGASGGRLSGGQKQRIAIARAIVRNPKILLLDEATSALDTESEKIVQEALDKARLGRTCV 1218
Query: 529 IVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
+++ RLS ++ D++IV ++GK +E+G + L+ + G++ +++
Sbjct: 1219 VIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRGLYYRLVE 1262
>emb|CAA64189.1| (X94434) ABC-transporter PlnG [Lactobacillus plantarum]
Length = 716
Score = 234 bits (591), Expect = 2e-60
Identities = 147/555 (26%), Positives = 277/555 (49%), Gaps = 6/555 (1%)
Query: 20 VHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLA 79
++ ++ LI ++S S ++ ID + + + +++ +F+ A
Sbjct: 167 INIVLAAVLITIISICGSY---FLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYA 223
Query: 80 GRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVR 139
+LL Q + + R + M FF +G+++SR T D +I L+ +
Sbjct: 224 QNFLLAVLGQRLSIEIILGYIRHVFELPMSFFATRRTGEIVSRFT-DASKIIDALASTIV 282
Query: 140 MLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIA 199
L + ++II +V N+TL + L+++ I + + + K +++
Sbjct: 283 SLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVILAFNKSFERLNQKEMESNAILS 342
Query: 200 SIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMS 259
S + GI+T+K+L+ E K E + ++ +K L + +
Sbjct: 343 SAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVLEV 402
Query: 260 TMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDS 319
+ + G +I N L+VGEL+ + + + PL+ + +Q + A +RL +V
Sbjct: 403 VVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLV 462
Query: 320 APKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKS 379
A + S G+I+ + V Y G VL V+ ++ +KV I G GSGKS
Sbjct: 463 ASEFEASRPIHNESQLNGDIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKS 522
Query: 380 SILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA-KP 438
+++KL+ FY+P G+V+++G NV I LR + Y+PQEP+IF+ +I EN+ L +
Sbjct: 523 TLVKLLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINYIPQEPYIFSATIEENLRLGNRS 582
Query: 439 NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVL 498
T++++ +A ++A I I + Y T + E G TLSGGQRQR+ +AR +L ++++
Sbjct: 583 GITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARRLLSPAQVLI 642
Query: 499 LDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPE 558
D+ S LDA TEK+L+++L + DKT + ++ RLS+ K + +IV+ DG++ E+G
Sbjct: 643 FDESTSGLDAITEKQLIDNL-VAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHA 701
Query: 559 ELIKKGGIFSEMMKA 573
L+ + G + +++ +
Sbjct: 702 ALLNEHGYYYDLINS 716
>gb|AAD43626.1|AF071411_1 (AF071411) multidrug resistance protein MDR [Aspergillus nidulans]
>gi|6856159|gb|AAF29805.1|AF173826_1 (AF173826)
ABC-transporter [Aspergillus nidulans]
Length = 1348
Score = 234 bits (591), Expect = 2e-60
Identities = 164/578 (28%), Positives = 295/578 (50%), Gaps = 26/578 (4%)
Query: 13 SYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY-----GLLIL 67
S+ R + LIGL +L VL AI + +R+ L+
Sbjct: 769 SFNRPEIPYMLIGLVFSVLAGGGQPTQAVLYAKAISTLSLPESQYSKLRHDADFWSLMFF 828
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK--TFSGQLISRITN 125
+VG++ + ++ + R AFR I R ++ FFDK +G L S ++
Sbjct: 829 VVGIIQFITQSTNGAAFAVCSERLIRRARSTAFRTILRQDIAFFDKEENSTGALTSFLST 888
Query: 126 DTERITRFLSFRVRMLLYSIFLI--IISLYYMVRMNITLTMVALITIAIVVGLNTTYAMK 183
+T+ ++ + +L + + I + + + L ++++ + + G Y +
Sbjct: 889 ETKHLSGVSGVTLGTILMTSTTLGAAIIIALAIGWKLALVCISVVPVLLACGFYRFYMLA 948
Query: 184 VRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENV-QTKFSQENEELYSLNVKAMKI 242
K+ ++ A+ A + I+T+ SL+ E +V + +Q + + + + ++
Sbjct: 949 QFQSRSKLAYEGS--ANFACEATSSIRTVASLTRERDVWEIYHAQLDAQGRTSLISVLRS 1006
Query: 243 TALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG- 301
+ LY ++ LV ++ F+YGG + + ++ F +++ ++ G
Sbjct: 1007 SLLYASSQALVF-FCVALGFWYGGTLLGHHEY---DIFRFFVCFSEILFGAQSAGTVFSF 1062
Query: 302 --DIQRSLAAASRLFDVIDSAPKSID--PPDAVEISNPRGEIEFRDVWLTYHTG--RTVL 355
D+ ++ AA+ + D P+ ID + ++ GEIEFR+V Y T + VL
Sbjct: 1063 APDMGKAKNAAAEFRRLFDRKPQ-IDNWSEEGEKLETVEGEIEFRNVHFRYPTRPEQPVL 1121
Query: 356 KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIV 415
+G+ VKPG+ V + GP G GKS+ + L+ RFY G +L+DG +++K+ + R +
Sbjct: 1122 RGLDLTVKPGQYVALVGPSGCGKSTTIALLERFYDAIAGSILVDGKDISKLNINSYRSFL 1181
Query: 416 AYVPQEPFIFNRSIRENIALA--KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ V QEP ++ +I+ENI L + + +E + +A K A I+DFI SLP+G++TVVG KG
Sbjct: 1182 SLVSQEPTLYQGTIKENILLGIVEDDVPEEFLIKACKDANIYDFIMSLPEGFNTVVGSKG 1241
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
LSGGQ+QR+A+ARA+L +PKI+LLD+ S LD+E+EK + L + +T + V+ R
Sbjct: 1242 GMLSGGQKQRVAIARALLRDPKILLLDEATSALDSESEKVVQAALDAAARGRTTIAVAHR 1301
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMM 571
LS ++ D + V GKIVE G EL++K G + E++
Sbjct: 1302 LSTIQKADVIYVFDQGKIVESGTHSELVQKKGRYYELV 1339
Score = 233 bits (587), Expect = 6e-60
Identities = 145/508 (28%), Positives = 268/508 (52%), Gaps = 26/508 (5%)
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYS 144
+ ++A +R +I R + +FDK +G++ +RIT DT I +S +V + L +
Sbjct: 188 IYTGEHATQKIREYYLESILRQNIGYFDKLGAGEVTTRITADTNLIQDGISEKVGLTLTA 247
Query: 145 I------FLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVI 198
+ F+I Y+ + + + T+VAL+ + +G + + +K K G
Sbjct: 248 LATFVTAFIIAYVKYWKLALICSSTIVALV---LTMGGGSQFIIKYSK---KSLDSYGAG 301
Query: 199 ASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAM 258
++A I+ I+ + ++ + ++ +E K + A F ++
Sbjct: 302 GTVAEEVISSIRNATAFGTQDKLAKQYEVHLDEAEKWGTKNQIVMGFMIGAMFGLMYSNY 361
Query: 259 STMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVID 318
F+ G + ++ + VG+++ L +L + L + ++AAA+++F ID
Sbjct: 362 GLGFWMGSRFLVDGAVDVGDILTVLMAILIGSFSLGNVSPNAQAFTNAVAAAAKIFGTID 421
Query: 319 SAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHTGR--TVLKGVSFKVKPGEKVLITGPP 374
+DP + + + G IE R+V Y + TV++ VS + G+ + GP
Sbjct: 422 RQ-SPLDPYSNEGKTLDHFEGHIELRNVKHIYPSRPEVTVMEDVSLSMPAGKTTALVGPS 480
Query: 375 GSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIA 434
GSGKS+++ L+ RFY P +G VL+DG ++ + LR+ ++ V QEP +F +I +NI
Sbjct: 481 GSGKSTVVGLVERFYMPVRGTVLLDGHDIKDLNLRWLRQQISLVSQEPVLFGTTIYKNIR 540
Query: 435 LA---------KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
+ +E +E AAK+A HDFI +LP+GY+T VG++G LSGGQ+QRIA
Sbjct: 541 HGLIGTKYENESEDKVRELIENAAKMANAHDFITALPEGYETNVGQRGFLLSGGQKQRIA 600
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+ARA++ +PKI+LLD+ S LD ++E + L+ + +T ++++ RLS +K ++V
Sbjct: 601 IARAVVSDPKILLLDEATSALDTKSEGVVQAALERAAEGRTTIVIAHRLSTIKTAHNIVV 660
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ +GKI E G +EL+ +GG + ++++A
Sbjct: 661 LVNGKIAEQGTHDELVDRGGAYRKLVEA 688
>pir||T26313 hypothetical protein W09D6.6 - Caenorhabditis elegans
>gi|3880598|emb|CAB04947.1| (Z82078) predicted using
Genefinder~contains similarity to Pfam domain: PF00005
(ABC transporter), Score=210.9, E-value=6.1e-60,
N=1~cDNA EST yk4g6.5 comes from this gene~cDNA EST
yk10f3.5 comes from this gene~cDNA EST yk135g3.5 comes
from this gene~cD>
Length = 772
Score = 234 bits (590), Expect = 2e-60
Identities = 114/303 (37%), Positives = 192/303 (62%)
Query: 271 QNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAV 330
+ TLTVG+ V F TY+L + PL G IQ++ +FD+++ + D P A+
Sbjct: 453 EKTLTVGDYVLFTTYLLQLYTPLNFFGTIYRVIQKAFVDMENMFDLMNDEVEVKDLPHAL 512
Query: 331 EISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYK 390
++PRG I +++ Y+TG V+K +SF++ G+ V + G GSGKS++++L+ R ++
Sbjct: 513 PYTDPRGTISVKNLTFEYNTGLPVIKNISFEIGNGQTVALVGSSGSGKSTLIRLLFRLFE 572
Query: 391 PTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAK 450
T+G + DG++V +LR+ + VPQ+ +FN +I NI +P+A+ EEV AAK
Sbjct: 573 STEGSIEFDGIDVRNYTMHSLRQQIGIVPQDTVLFNDTIMYNIRFGRPDASDEEVIEAAK 632
Query: 451 IAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAET 510
A IH+ I SLP+GY T+VGE+G+ LSGG++QR+A+AR +L P+ + LD+ S LD T
Sbjct: 633 AAMIHEKITSLPEGYATMVGERGLKLSGGEKQRVAIARTILKKPQFIFLDEATSALDTPT 692
Query: 511 EKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
E+ + + L+++ + +T ++V+ RLS V D ++V+ G I+E G +EL+ + G ++ M
Sbjct: 693 ERAIQKCLEKLCKSRTGVVVAHRLSTVVNADLILVLDKGIILERGNHKELLAQQGTYASM 752
Query: 571 MKA 573
+A
Sbjct: 753 WEA 755
>gb|AAD02044.1| (AF035964) ATP-binding protein A [Brucella abortus]
Length = 622
Score = 233 bits (589), Expect = 3e-60
Identities = 155/573 (27%), Positives = 300/573 (52%), Gaps = 30/573 (5%)
Query: 23 LIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRY 82
LI + + L ++ +IV L + + ++ +++++ G ++LVG L GV +
Sbjct: 52 LIAVIEVSLFAFLGNIVDWLSNQSRETFLANEGWRLSLIAG--VVLVG-LPGVVLIHS-- 106
Query: 83 LLVKAAQYAVYYLRMD--AFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRM 140
L++ Y +R+ R + R M FF F+G++ +++ + + + +
Sbjct: 107 LIIHQTLLGNYPMRVRWLMHRYLIRQSMTFFQDEFAGRISTKLMQTALAVRETVMKLLDV 166
Query: 141 LLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIAS 200
L Y I +L+ ++ L + + + + L + ++R + ++ +
Sbjct: 167 LNYVIVYFAGALFIAAAADMRLMIPFAVWLVAYIVLLRIFIPRLRVVSEEQADARSTMTG 226
Query: 201 IATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV-KAMKITALYGNAPFLVLGLAMS 259
+ I T+K S +T + +E+ +++ V + M++ L+ +L L +
Sbjct: 227 RIVDSYTNIATVKLFSHSSREET-YVRESLDIFMDTVHRQMRLVTLFHFTLYLSNCLLLF 285
Query: 260 TMFYYGGKAIIQNTLTVGELVAFLTYMLTM-------MWPLRALGFTIGDIQRSLAAASR 312
+ G I +++G + + +L + MW + AL IG ++ + +R
Sbjct: 286 AVGAIGIGLWINEAVSIGAVAVGIGLVLRLNGMSQWIMWEMSALFENIGTVEDGITTLAR 345
Query: 313 LFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITG 372
+V+D P+A + RG+++F ++ Y G+ V+K +S + G+KV + G
Sbjct: 346 PHEVVDV-------PNAPALKVARGDLDFDEIGFHYGRGKGVIKNLSLTIPAGQKVGLVG 398
Query: 373 PPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIREN 432
G+GKS+++ L+ RFY KG +LIDG +++++ ++LR + V Q+ + +RS+REN
Sbjct: 399 RSGAGKSTLVNLLLRFYDLEKGRILIDGQDISQVTQDSLRANIGMVTQDTSLLHRSVREN 458
Query: 433 IALAKPNATQEEVERAAKIAKIHDFIASL--PKG---YDTVVGEKGITLSGGQRQRIALA 487
I +P+A++E +++A ++A+ FI L PKG D VGE+G+ LSGGQRQRIA+A
Sbjct: 459 IMYGRPDASEEMLQQAIRLAQADQFIPQLVDPKGRRGLDAHVGERGVKLSGGQRQRIAIA 518
Query: 488 RAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMK 547
R ML + I++LD+ S LD+E E + + L +++ KT + ++ RLS + +DR++VM
Sbjct: 519 RVMLKDAPILILDEATSALDSEVEAAIQDSLNTLMEGKTVIAIAHRLSTIAALDRLVVMD 578
Query: 548 DGKIVEDGKPEELIKKGGIFSEM--MKAGGVYG 578
G+IVEDG EEL+ GGI++ + ++GG G
Sbjct: 579 KGRIVEDGTHEELVALGGIYASLWARQSGGFLG 611
>gb|AAF50670.1| (AE003563) CG10226 gene product [Drosophila melanogaster]
Length = 1320
Score = 233 bits (588), Expect = 4e-60
Identities = 172/541 (31%), Positives = 277/541 (50%), Gaps = 38/541 (7%)
Query: 57 KVAIRYGLLILLVGVL---NGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDK 113
K ++ +G+L+ L +L +GV+ + + A +R + F+A R E+ + D
Sbjct: 120 KDSVSFGILMTLNTLLMLFSGVYYVDA---FNRLALKLTVRMRREFFKATLRQEIGWHDM 176
Query: 114 TFSGQLISRITNDTERI----TRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALIT 169
RIT++ E+I L V ++ I +++S Y + L +V I
Sbjct: 177 AKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIY--GWKLALAIVFYIP 234
Query: 170 IAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQEN 229
+ +VV N+ A + + + +S+ I I+T+ + E + ++
Sbjct: 235 LTLVV--NSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSESLRY---- 288
Query: 230 EELYSLNVKAMK----ITALYGNAPFLVLGLAMSTMFYYGGKAII----------QNTLT 275
+ L +KA K + L +L + + F+YG I+ + T
Sbjct: 289 DSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFWYGANLILYYRDPSIPIDEREYT 348
Query: 276 VGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP-PDAVEISN 334
++ ++ ++ + + + +AS + DVID IDP A +I N
Sbjct: 349 PAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAILDVIDRT-SLIDPLSKAGKILN 407
Query: 335 P--RGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYK 390
+G +EFRDV+ Y V L+G++ V+ G+ V + GP G GKS+ ++L+ RFY
Sbjct: 408 YGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYD 467
Query: 391 PTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAK 450
P G+VL+DG +V K + LR +A V QEP +F SI ENI KP ATQ+EVE AAK
Sbjct: 468 PVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQKEVEDAAK 527
Query: 451 IAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAET 510
A HDFI +L KGYDT + EKG+ LSGGQRQRIA+ARA++ PKI+LLD+ S LD +
Sbjct: 528 AANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYHS 587
Query: 511 EKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
EK + L + + +T L+VS RLS ++ R++ +++GK VE G EEL+K G + +M
Sbjct: 588 EKLVQAALDKACKGRTTLVVSHRLSAIRHAHRIVYIENGKAVEQGTHEELMKLEGFYHKM 647
Query: 571 M 571
+
Sbjct: 648 V 648
Score = 222 bits (559), Expect = 1e-56
Identities = 160/590 (27%), Positives = 287/590 (48%), Gaps = 24/590 (4%)
Query: 5 INQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRN---AIDKGVSTGAYKVAIR 61
I+ R+L + R +IG L T + V++ ++ K + +
Sbjct: 727 ISTFFRILGWARPEWSFLIIGAICAGLYGVTMPVFSVVLAELYGSLAKPTDEEVLEQSAS 786
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS--GQL 119
++ L++G+ GV + A + +R FR I EM +FD+ + G L
Sbjct: 787 MAIISLVIGIAAGVVCYIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGAL 846
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R++ D + + F + ++ + I S+ + L ++ L T +V
Sbjct: 847 SARLSGDAASVQGAIGFPLSNIIQAFTNFICSIAIAFPYSWELALICLSTSPFMVASIVF 906
Query: 180 YAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKA 239
A K + + IAT TI I+T+ L EE + + +E E +
Sbjct: 907 EARFGEKSALKEKEVLEETSRIATETITQIRTVAGLRREEELIKIYDKEVERYRHQILSR 966
Query: 240 MKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL-RALGF 298
+K L + ++ + YGG + ++ ML ++ L ++L F
Sbjct: 967 LKWRGLVNSLGKSLMFFGYAVTLTYGGHMCADGKIKFETIMKISNTMLYGLFILAQSLAF 1026
Query: 299 TIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEIS-NPRGE----------IEFRDVWLT 347
T +L +A+R++++ID P+ I P++ EI N G + +R + +
Sbjct: 1027 TPA-FNAALLSANRMYEIIDRKPQ-IQSPESFEIQQNGNGTAYKTNVVQQGVSYRGLNFS 1084
Query: 348 YHTGR--TVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAK 405
Y + VL+ + + G+ V + G GSGKS+ ++L+ R+Y P +G++LID ++
Sbjct: 1085 YPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKILIDQESIHH 1144
Query: 406 -IKTENLRKIVAYVPQEPFIFNRSIRENIALAKPN--ATQEEVERAAKIAKIHDFIASLP 462
+ + LR+ + V QEP +F +SI +NI + +++ AAK+A H+FI SLP
Sbjct: 1145 DMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMANAHEFIMSLP 1204
Query: 463 KGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEIL 522
YDTV+G KG LSGGQ+QRIA+ARAM+ NPKI+LLD+ S LD ++E+ + + L
Sbjct: 1205 AQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSAC 1264
Query: 523 QDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
+T ++++ RLS ++ + + V++ GKIVE G +L+ K GI+S++ +
Sbjct: 1265 SGRTCIVIAHRLSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSKLYR 1314
>pir||T48418 ABC transporter-like protein - Arabidopsis thaliana
>gi|7406401|emb|CAB85511.1| (AL162873) ABC
transporter-like protein [Arabidopsis thaliana]
Length = 634
Score = 233 bits (587), Expect = 6e-60
Identities = 157/561 (27%), Positives = 290/561 (50%), Gaps = 16/561 (2%)
Query: 4 SINQLIRLLSYLRGHAVHFLIG-LFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY 62
S+ L + YL+ + L+G L + + + IVP L + ++ A +
Sbjct: 58 SLKALETIKPYLQSESKTVLLGWLCSCVSVVSLSQIVPRL--GSFTSNLNANAASLTKLK 115
Query: 63 GLLILLVGVLNGVFSLAGRYL----LVKAAQYAVYYLRMDAFRAIQRHEMEFFDK---TF 115
G ++L G++ + + YL L +AA VY +R+ A+R + E+EFF+
Sbjct: 116 GECLVLAGLV--LAKVVAYYLQQAFLWEAALNTVYKIRVFAYRRVLERELEFFEGGNGIS 173
Query: 116 SGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVG 175
SG + RIT + + + + ++ S I + +M+ + LT+V+ + I V
Sbjct: 174 SGDIAYRITAEASEVADTIYALLNTVVPSAIQISVMTAHMIVASPALTLVSAMVIPSVAL 233
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
L ++R I K + + +++ + I +K+ + E + +F +
Sbjct: 234 LIAYLGDRLRKISRKAQIASAQLSTYLNEVLPAILFVKANNAEISESVRFQRFARADLDE 293
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
K K+ +L V+ L ++F G + ++L+ +V+F+ + ++ P++
Sbjct: 294 RFKKKKMKSLIPQI-VQVMYLGSLSIFCVGAVILAGSSLSSSAIVSFVASLAFLIDPVQD 352
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT-V 354
LG ++++ A RLFD+ K I+ P+A+++ GE+E D+ Y V
Sbjct: 353 LGKAYNELKQGEPAIERLFDLTSLESKVIERPEAIQLEKVAGEVELCDISFKYDENMLPV 412
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
L G++ +K GE V + GP G GK++++KL+ R Y+P+ G ++ID +++ IK E+LRK
Sbjct: 413 LDGLNLHIKAGETVALVGPSGGGKTTLIKLLLRLYEPSSGSIIIDKIDIKDIKLESLRKH 472
Query: 415 VAYVPQEPFIFNRSIRENIALAK--PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEK 472
V V Q+ +F+ +I +NI + VE AAK A +FI +LP+GY+T VG +
Sbjct: 473 VGLVSQDTTLFSGTIADNIGYRDLTTGIDMKRVELAAKTANADEFIRNLPEGYNTGVGPR 532
Query: 473 GITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQ 532
G +LSGGQ+QR+A+ARA+ I++LD+ S LD+ +E + E L+ ++QD T ++++
Sbjct: 533 GSSLSGGQKQRLAIARALYQKSSILILDEATSALDSLSELLVREALERVMQDHTVIVIAH 592
Query: 533 RLSLVKLVDRVIVMKDGKIVE 553
RL V + RV +++ GK+ E
Sbjct: 593 RLETVMMAQRVFLVERGKLKE 613
>pir||T21268 hypothetical protein F22E10.3 - Caenorhabditis elegans
>gi|3876293|emb|CAA91801.1| (Z67882) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=438.6,
E-value=1.7e-128, N=2; PF00664 (ABC transporter
transmembrane region.), Score=275.4, E-value=2.3e-79,
N=2~cDNA EST yk11d11.3 comes from this gene~cDNA EST
yk11d11.5 co>
Length = 1327
Score = 231 bits (584), Expect = 1e-59
Identities = 138/479 (28%), Positives = 252/479 (51%), Gaps = 10/479 (2%)
Query: 102 AIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLL--YSIFLIIISLYYMVRMN 159
++ R +FDK SG + +++ + ERI + ++ +LL +++ + I + Y+
Sbjct: 190 SVLRQNAGWFDKNHSGTITTKLNDSMERIREGIGDKLGVLLRGFAMLIAAIVVAYIYEWR 249
Query: 160 ITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEE 219
+ M+ + + M I + I G SIA ++ G++T+++ + +E
Sbjct: 250 LASMMLGVAPTCCICMSLLARQMTSTTIKELIG--VGKAGSIAEESLMGVRTVQAFNGQE 307
Query: 220 NVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTV-GE 278
+ ++ E E+ V + +G F L + YG + +T G+
Sbjct: 308 EMVGRYEAELEKGRKFAVWKGFWSGFFGGLFFFWLFSFLGCGMLYGAYLLKVGIITTPGD 367
Query: 279 LVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAV--EISNPR 336
+ + ML + L + + + + +A+ ++ ID PK IDP + N
Sbjct: 368 VFIVVMSMLLGAYFLGLISPHMMVLLNARVSAASIYQTIDRVPK-IDPYSKAGKRLQNVV 426
Query: 337 GEIEFRDVWLTYHTGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKG 394
G ++F +V Y + + +L G++ V+PG V + G G GKS+ + L+ R Y+P G
Sbjct: 427 GRVKFENVHFRYPSRKDAKILNGLNLVVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAG 486
Query: 395 EVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKI 454
V IDG +V ++ E LR V V QEP +FN +I N+ + P +T+E + K+A
Sbjct: 487 NVTIDGTDVRELNIEWLRNTVGIVQQEPILFNDTIHNNLLIGNPGSTRETMIEVCKMANA 546
Query: 455 HDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKL 514
HDFI +PKGYDT++G+ G+ LSGGQ+QR+A+AR ++ +PK++LLD+ S LDA++E +
Sbjct: 547 HDFIEKMPKGYDTLIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESIV 606
Query: 515 VEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
L + +T ++++ RLS ++ D+++ + G IVE G EEL++ GG + +++KA
Sbjct: 607 QSALNNASKGRTTIMIAHRLSTIREADKIVFFEKGVIVEAGNHEELVRLGGRYFDLVKA 665
Score = 203 bits (511), Expect = 5e-51
Identities = 148/515 (28%), Positives = 260/515 (49%), Gaps = 20/515 (3%)
Query: 69 VGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS--GQLISRITND 126
VGV LA L ++ R+ +FR + + +FD G+LI+R+ +D
Sbjct: 816 VGVGVWFSQLASSVLFAVVSENLSMRFRVQSFRNLLYQDASYFDNPAHAPGKLITRLASD 875
Query: 127 TERITRFLSFRVRMLLYSIFLII----ISLYYMVRMNITLTMVALITIAIVVGLNTTYA- 181
I + R+ ++Y++ II I+ Y ++ I T + L+ +++GL +
Sbjct: 876 APNIKAVVDARMLQVIYALAAIIANIAIAFIYCWQIGILGTSLILLLAFVMIGLAYKISL 935
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
M V I Q IA I +KTI+ L+ E + +++ +K
Sbjct: 936 MNVEQI------QNDDAGRIAIEIIENVKTIQLLTRCELFFDHYQTSSKQQKRSELKKGM 989
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
I A+ + + M + G + I Q + + + M+ +
Sbjct: 990 IEAINYSLTQSFMYFMMCFTYAVGIRIIYQGDKSSDDTFKGIIAMMLGAVAVMNSAQYFP 1049
Query: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP--RGEIEFRDVWLTYHTG--RTVLKG 357
+ ++ AA LF++I P++ D +E P RG I F +V +Y + ++KG
Sbjct: 1050 EFVKAKTAAGMLFNIIYRKPRT---GDLMEGDRPEIRGNILFENVKFSYPQRPLQPIMKG 1106
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
+ + G+ V + GP GSGKS+ + ++ RFY T G + IDG ++ K+ +LR +A
Sbjct: 1107 LQWTALRGQTVALVGPSGSGKSTNIGMLERFYDVTGGALRIDGQDIRKLSLFHLRTQMAL 1166
Query: 418 VPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLS 477
V QEP +F +IREN+ L + E++ +A ++A + F+A+LP G DT VGEKG LS
Sbjct: 1167 VGQEPRLFAGTIRENVCLGLKDVPLEKINQALELANANRFLANLPAGIDTDVGEKGGQLS 1226
Query: 478 GGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLV 537
GGQ+QRIA+ARA++ +PKI+LLD+ S LD+E+E+ + E L + +T + ++ RLS +
Sbjct: 1227 GGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEALDRAREGRTCITIAHRLSSI 1286
Query: 538 KLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
+ D ++ + GK+ E G +L+ + G + +++K
Sbjct: 1287 QNSDLIVYIDKGKVQEAGNHTQLMHQKGRYYKLIK 1321
>gb|AAD25925.1|AF082072_1 (AF082072) ABC transporter protein AtrC [Aspergillus nidulans]
Length = 1293
Score = 231 bits (584), Expect = 1e-59
Identities = 170/594 (28%), Positives = 291/594 (48%), Gaps = 46/594 (7%)
Query: 13 SYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKV------------AI 60
S ++ H + + GLF I ++ ++ ID GA K+ A+
Sbjct: 63 SSVQDHVIR-VTGLFAAIACGAALPMMTLVFGTLIDNFNDWGAGKLSPDEFRSHVSQNAL 121
Query: 61 RYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
+ L + + VL+ F+ A L A V LR D R+I R ++ +FD G +
Sbjct: 122 WFTYLFISIFVLSS-FNTA---CLRLTATRCVRALRHDFIRSILRQDLSYFDNCLPGTVA 177
Query: 121 SRITNDTERITRFLSFRVRMLLYSI------FLIIISLYYMVRMNITLTM-VALITIAIV 173
+ ++N+ + + L ++ + + + F++ + + + + + T+ +A++ I +
Sbjct: 178 TVLSNNADLVEIGLGEKLGIAIEGVAQLCAAFVVAFARQWKLTLVVAATLPLAMLVIVVT 237
Query: 174 VGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELY 233
V L T K+ IY K IA +A +K+ + +Q ++ E
Sbjct: 238 VILETRITTKILAIYSKA-------GGIAEEALASTHIVKAYNAASKLQARYDSYLERAT 290
Query: 234 SLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTL-TVGELVAFLTYMLTMMWP 292
L VK I + A F ++ A + ++YG + +++ + + G L+ LT +L
Sbjct: 291 QLGVKRGPIRGIQYGAQFAIMFCAYALAWFYGIRLLVKGEIESGGYLITVLTSVLIGSQS 350
Query: 293 LRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDP--PDAVEISNPRGEIEFRDVWLTYHT 350
L +G IG++ ++ AAA LF VID P +ID D ++ G I FR+V Y +
Sbjct: 351 LTLIGPFIGEVSKTAAAAQELFQVIDRKP-NIDSLSSDGRTLTGVTGHISFRNVSFAYPS 409
Query: 351 GRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
+V L V+ + G+ I G GSGKS+IL L++RF+ P G VL+DG + ++
Sbjct: 410 RPSVRVLDDVTVDFEAGKTTAIVGSSGSGKSTILALVSRFFDPVSGSVLLDGHPIHELNI 469
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIA---------LAKPNATQEEVERAAKIAKIHDFIA 459
LR + V QEP +F+ SI N+ L + + V+ A + A H FI
Sbjct: 470 RWLRGQIGSVQQEPVLFSESIFANVCHGFFRTDMDLLPEHERRIRVQEACEAAFAHHFIQ 529
Query: 460 SLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLK 519
LP+ YDT VG LSGGQ+QRIA+AR+++ NP I+LLD+ S LD E + L
Sbjct: 530 GLPEQYDTPVGAGDGLLSGGQKQRIAIARSIIRNPPILLLDEATSALDPNAEGTVQAALN 589
Query: 520 EILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ + +T +IV+ RLS V+ D ++V++ G++VE G EL+ K G + +++ A
Sbjct: 590 NVSKTRTTIIVAHRLSTVQRADNIVVLRKGRVVEQGSHRELLAKKGTYFDLVAA 643
Score = 217 bits (547), Expect = 3e-55
Identities = 160/570 (28%), Positives = 290/570 (50%), Gaps = 55/570 (9%)
Query: 39 VPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMD 98
+P + + KG G + + +LI G L F++A +L + Y Y
Sbjct: 745 LPAMASEMLHKGNFWGIIYIVLAVSVLICYAG-LGFFFTVAASFL---SGTYRSRY---- 796
Query: 99 AFRAIQRHEMEFFDKT--FSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMV 156
F A+ ++ FF++ +G + +++ D +RI +S + +L + ++ S +
Sbjct: 797 -FAAMLNQDVSFFEEEDQSAGVMTGQLSTDPQRIEDLISLCLGFILLVVVNVLASCILAL 855
Query: 157 RMNITLTMVALITIA--------IVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAG 208
+ L +VA+ + V L T + +Y + A AT I+
Sbjct: 856 AVGWRLALVAIFGCLPPLFLAGYVRVRLEITCQERTTRLYLES-------ARFATEAISA 908
Query: 209 IKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTM---FYYG 265
I+T+ SL++EE V + +E L + K ++IT + L L ++T+ F+YG
Sbjct: 909 IRTVASLTLEEKVIQMY---DERLSHTSPKFIRITLVSAILLGLCESLYLATLGLIFWYG 965
Query: 266 GKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG---DIQRSLAAASRLFDVIDSAPK 322
K + Q V F + +++ +A GF +G + ++ AA+ + ++ S P
Sbjct: 966 VKLLSQGEYNVE---TFFMVFVAVIFGGQAAGFLLGYTVNTAKAHTAANNIIHILGSRPS 1022
Query: 323 ---SIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
S + V++ + IEF+DV +Y TV L+G+SFKVK GE + + G G G
Sbjct: 1023 INASTGKQETVQLDSDTA-IEFKDVHFSYPARPTVPVLQGLSFKVKKGEHIGLVGASGCG 1081
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALA- 436
K++++ L+ RFY+ GE+ I+G+ + I + R + V Q P ++ SIR+N+ +
Sbjct: 1082 KTTVISLLERFYEAGSGEIFINGIPLHDIDVHSHRARIGLVTQNPTLYQGSIRDNVLIGI 1141
Query: 437 --------KPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALAR 488
+ +E++ +A K A I DFI SLP+G T G +G+ LSGGQRQRIA+AR
Sbjct: 1142 SISHQNEELDSQIEEKLTKAYKDANIQDFIQSLPEGQQTDPGTRGLALSGGQRQRIAIAR 1201
Query: 489 AMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIVSQRLSLVKLVDRVIVM 546
A++ +P+++L D+ S LD E E+ + E ++ + +T + V+ RL+ V+ DR++V+
Sbjct: 1202 ALIRDPELLLFDEATSALDTENERLVQEAIERVSHGPGRTTISVAHRLTTVRRCDRILVL 1261
Query: 547 KDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
+G++ E+G EL+ +GG + +M+ A G+
Sbjct: 1262 HEGRVEEEGTHAELMARGGRYYQMVLAQGL 1291
>gb|AAB69130.1| (U63320) P-glycoprotein [Leishmania tropica]
Length = 1341
Score = 231 bits (583), Expect = 2e-59
Identities = 158/534 (29%), Positives = 279/534 (51%), Gaps = 17/534 (3%)
Query: 59 AIRYGLLILLVGVLNGVFSLAGRYLL--VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
A + L+++ VG+ G+F G ++L AA +R++ FRA+ R ++ + D+
Sbjct: 172 AAKTSLIMVYVGI--GMFVACGGHVLCWTVAASRQERRIRLNFFRAVLRQDIGWHDERSP 229
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLY--YMVRMNITLTMVALITIAIVV 174
G+L +R+T DT I ++ ++ + + + II ++ +TL MV ++ IV+
Sbjct: 230 GELTARMTGDTRVIQNGINDKLSQGIMNGAMGIIGYIAGFVFSWELTLVMVGMMPFIIVM 289
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
V + + R S+AT + I+T++ E+ +F++
Sbjct: 290 A--AIIGNIVSKMTESSRKHFAKAGSLATEVMENIRTVQVFGREDYELQRFAEAVLHAQD 347
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
++ +L ++ L+ + F++G + + ++++ +L + L
Sbjct: 348 RGIRKEFAGSLSEAVIMALVYLSYTIAFFFGSYLVEWGRRDMADIISTFLAVLMGSFGLG 407
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+ + S AAA +F ID P D V ++ + IEFR+V +Y T +
Sbjct: 408 FVAPSAAAFTESRAAAYEIFKAIDRVPPVDIDADGVPVTGFKQSIEFRNVRFSYPTRPDM 467
Query: 355 L--KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR 412
+ + ++ K+K G+KV +G G GKSS++ LI RFY P G VL DGV++ ++ + R
Sbjct: 468 ILFRDLNLKIKCGQKVAFSGSSGCGKSSMIGLIQRFYDPAGGAVLCDGVDMRELCLHDWR 527
Query: 413 KIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEK 472
+ V QEP +F ++ EN+ + KPNAT+EEV A + A +HD I SLP Y+T VG
Sbjct: 528 DQIGIVSQEPILFAGTMMENVRVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAV 587
Query: 473 GITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIV 530
G LSGGQ+QRIA+ARA++ P I+LLD+ S LD ++E ++ L ++++ T +++
Sbjct: 588 GSQLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLMERGGVTVIVI 647
Query: 531 SQRLSLVKLVDRVIVMK-DG----KIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
+ RL+ ++ VD + +K DG KI E G +EL++ GG F+ M + GV G
Sbjct: 648 AHRLATIRNVDCIYCVKYDGAEGSKIAESGTFDELMELGGEFAAMARIQGVSTG 701
Score = 205 bits (516), Expect = 1e-51
Identities = 162/567 (28%), Positives = 283/567 (49%), Gaps = 38/567 (6%)
Query: 30 ILMSYTNSIVPVLIRNAIDKGVS-----TGAYK-VAIRYGLLILLVGVLNGVFSLAGRYL 83
ILM Y ++ VL +++K V T Y + I + + L L+G + AG +L
Sbjct: 793 ILMGY---MLRVLGEYSVNKNVEQLRSGTNLYAPLFILFAVANFLGWALHGFYGYAGEHL 849
Query: 84 LVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITRFLSFRVRML 141
K +R+ FR I R +M FFD +G L ++ D E + + + +
Sbjct: 850 TTK--------IRVLLFRQIMRQDMNFFDIPGRDAGTLAGMLSGDCEAVHQLWGPSIGLK 901
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
+ ++ ++ + L +VAL + +++G + M + Y K + + +I
Sbjct: 902 VQTVCIVASGVVVSFIYQWKLALVALACMPLLIGCSLAERMMMNG-YTKSK-EGDTSDTI 959
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT-ALYGNAPFLVLGLAMST 260
T ++ ++T+ S +++ + F +VK I ++YG F+ A +
Sbjct: 960 VTEALSSVRTVTSFNMKADRVEAFEATLRVEAPRSVKKGIIAGSIYGATQFIYYS-AYAL 1018
Query: 261 MFYYGGKAIIQNTLTVGELVAFLTYML---TMMWPLRALGFTIGDIQRSLAAASRLFDVI 317
F+YG K I + ++ T +L A + D +RS A R+F VI
Sbjct: 1019 CFWYGSKLIDRGEAQFTNVMIASTSILFGAQNAGEAGAFATKLADAERS---AKRVFSVI 1075
Query: 318 DSAPKSIDPPDAVEISNPRG-EIEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPP 374
D P +D + + +G +++F+ V Y + VL+ V+ + G + G
Sbjct: 1076 DRVP-DVDIEQSGDKDLGKGCDVDFQRVQFIYSARPKQVVLESVNLRFGDGTVNGLMGQT 1134
Query: 375 GSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIA 434
G GKS+I++++ARFY G + ++G +++ + R+ ++ V QEP +F+ ++RENI
Sbjct: 1135 GCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIAEWRRNISVVLQEPNLFSGTVRENIR 1194
Query: 435 LAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNP 494
A+ +AT EEVE AA++A IH I P GY+T VG KG LSGGQ+QR+A+AR +L P
Sbjct: 1195 YAREDATDEEVEEAARLAHIHWEIVKWPDGYNTEVGYKGSALSGGQKQRVAIARGLLRRP 1254
Query: 495 KIVLLDDPVSNLDAETEKKLVEDLK--EILQDKTALIVSQRLSLVKLVDRVIVMKDGKIV 552
K++LLD+ S LD TE K+ E + + + T++ ++ RL+ ++ D++I++ G I+
Sbjct: 1255 KLLLLDEATSALDNVTEAKVQEGINAYQAKYEVTSVSIAHRLTTIRHCDQIILLDSGHII 1314
Query: 553 EDGKPEELIKKGGIFSEMMKAGGVYGG 579
E G EEL+ GG E M +Y G
Sbjct: 1315 EQGSHEELMALGG---EYMMRYDLYTG 1338
>pir||T41534 leptomycin B resistance protein, ABC transporter - fission yeast
(Schizosaccharomyces pombe) >gi|3426129|emb|CAA20363.1|
(AL031307) leptomycin b resistance protein, abc
transporter [Schizosaccharomyces pombe]
Length = 1362
Score = 231 bits (583), Expect = 2e-59
Identities = 166/531 (31%), Positives = 274/531 (51%), Gaps = 35/531 (6%)
Query: 67 LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITND 126
L++ ++ + + A + + +R FR + R ++EFFD++ N
Sbjct: 843 LILAIVQFFAYAISNFAMTYAMEAVLQRIRYHLFRTLLRQDVEFFDRS---------ENT 893
Query: 127 TERITRFLSFRVRML-------LYSIFLIIISLYYMVRMNIT----LTMVALITIAIVVG 175
IT LS +++ L L + F I+ ++ + +++ L +V L T +++
Sbjct: 894 VGAITTSLSTKIQSLEGLSGPTLGTFFQILTNIISVTILSLATGWKLGLVTLSTSPVIIT 953
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + +K+ A+ A + + I+T+ SL+ EENV ++ +
Sbjct: 954 AGYYRVRALDQVQEKLSAAYKESAAFACESTSAIRTVASLNREENVFAEYCDSLIKPGRE 1013
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+ A + L+ +A V L + F+YG + + + V F T + +++ ++
Sbjct: 1014 SAIASLKSGLFFSAAQGVTFLINALTFWYGSTLMRKGEYNI---VQFYTCFIAIVFGIQQ 1070
Query: 296 LGFTIG---DIQRSLAAASRLFDVIDSAPKSIDPPDA----VEISNPRGEIEFRDVWLTY 348
G G D+ ++ AAA + + +S PK ID VE S IEFR V +Y
Sbjct: 1071 AGQFFGYSADVTKAKAAAGEIKYLSESKPK-IDTWSTEGKKVE-SLQSAAIEFRQVEFSY 1128
Query: 349 HTGR--TVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
T R VL+G++ VKPG+ V G G GKS+ + LI RFY G VL+DGVNV
Sbjct: 1129 PTRRHIKVLRGLNLTVKPGQFVAFVGSSGCGKSTTIGLIERFYDCDNGAVLVDGVNVRDY 1188
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGY 465
+ RK +A V QEP ++ ++RENI L A + ++EE+ A K A IH+FI LP GY
Sbjct: 1189 NINDYRKQIALVSQEPTLYQGTVRENIVLGASKDVSEEEMIEACKKANIHEFILGLPNGY 1248
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
+T+ G+KG +LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD+ +EK + E L Q +
Sbjct: 1249 NTLCGQKGSSLSGGQKQRIAIARALIRNPKILLLDEATSALDSHSEKVVQEALNAASQGR 1308
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
T + ++ RLS ++ D + V G I E G EL+K+ G + E++ G+
Sbjct: 1309 TTVAIAHRLSSIQDADCIFVFDGGVIAEAGTHAELVKQRGRYYELVVEQGL 1359
Score = 218 bits (550), Expect = 1e-55
Identities = 169/611 (27%), Positives = 300/611 (48%), Gaps = 62/611 (10%)
Query: 10 RLLSY---------LRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAI 60
R+LSY L G GL + ++ + + A KG S+ + V
Sbjct: 82 RILSYADKWDIMLQLAGTITGIGAGLGMPLMSLVSGQLAQAFTDLASGKGASSFQHTVD- 140
Query: 61 RYGLLILLVGVLNGVFSLAGRYLL--VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQ 118
+ L + + + GVF + Y + + A + +R D AI + +FD+ +G+
Sbjct: 141 HFCLYFIYIAI--GVFGCSYIYTVTFIIAGERIARRIRQDYLHAILSQNIGYFDRLGAGE 198
Query: 119 LISRITNDTERITRFLSFRVRMLLYSI--FLIIISLYYMVRMNITLTMVALI-TIAIVVG 175
+ +RIT DT I L +V ++ ++I F+ + ++ TL + ++ I +G
Sbjct: 199 ITTRITTDTNFIQDGLGEKVGLVFFAIATFVSGFVIAFIRHWKFTLILSSMFPAICGGIG 258
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEE---NVQTKFSQENEEL 232
L + K + G IA +A S VEE N++ F+ +++
Sbjct: 259 LGVPFITK---------NTKGQIAVVAES---------STFVEEVFSNIRNAFAFGTQDI 300
Query: 233 YSLNVKAMKITAL-YGNAPFLVLGLAMSTMFYY-----------GGKAIIQNTLTVGELV 280
+ ITA +G + +GL + MF+ GG+ + L V +L+
Sbjct: 301 LAKLYNKYLITAQRFGINKAIAMGLMVGWMFFVAYGVYGLAFWEGGRLLHAGDLDVSKLI 360
Query: 281 AFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDS-APKSIDPPDAVEISNPRGEI 339
+L + L + + +AA ++FD ID +P + P + + +GEI
Sbjct: 361 GCFFAVLIASYSLANISPKMQSFVSCASAAKKIFDTIDRVSPINAFTPTGDVVKDIKGEI 420
Query: 340 EFRDVWLTYHTGRTVLKGVSFKV--KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVL 397
E +++ Y T VL +F + G+ + G GSGKS+I+ L+ RFY P G+V
Sbjct: 421 ELKNIRFVYPTRPEVLVLDNFSLVCPSGKITALVGASGSGKSTIIGLVERFYDPIGGQVF 480
Query: 398 IDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNA-----TQEEVER----A 448
+DG ++ + +LR ++ V QEP +F ++ ENI P+ ++EE+ER A
Sbjct: 481 LDGKDLRTLNVASLRNQISLVQQEPVLFATTVFENITYGLPDTIKGTLSKEELERRVYDA 540
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
AK+A +DFI +LP+ + T VG++G +SGGQ+QRIA+ARA++ +PKI+LLD+ S LD+
Sbjct: 541 AKLANAYDFIMTLPEQFSTNVGQRGFLMSGGQKQRIAIARAVISDPKILLLDEATSALDS 600
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFS 568
++E + + L + +T ++++ RLS ++ D ++V+ GKIVE G EL+ G ++
Sbjct: 601 KSEVLVQKALDNASRSRTTIVIAHRLSTIRNADNIVVVNAGKIVEQGSHNELLDLNGAYA 660
Query: 569 EMMKAGGVYGG 579
+++A + GG
Sbjct: 661 RLVEAQKLSGG 671
>emb|CAB05915.1| (Z83325) transport-associated protein [Salmo salar]
Length = 554
Score = 231 bits (582), Expect = 2e-59
Identities = 144/508 (28%), Positives = 266/508 (52%), Gaps = 19/508 (3%)
Query: 9 IRLLSYLRGHAVHFLIGLFLIILMSY-TNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
+R+L + R + L+G F+ + ++ + + +P ID + YK +IL
Sbjct: 56 MRVLYFYRPDTL-LLVGAFIFLALAVLSETFIPFYTGKVID--ILASQYKWNDFLTAIIL 112
Query: 68 LVGVLNGVFSLAGRY-------LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLI 120
+ G++SL + L + A ++++ F A+ + E+ FF+ +G +
Sbjct: 113 M-----GLYSLGSSFSAGCRGGLFMCAINSFTCRMKVELFGALVKQEISFFETIKTGDIT 167
Query: 121 SRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTY 180
SR++ DT ++ R L+ V +LL ++ + L M+ ++ LT++ L+ I L Y
Sbjct: 168 SRLSTDTTKMARALALNVNVLLRTLIKTVGMLSLMMSLSWKLTLLMLMETPITGLLQGVY 227
Query: 181 AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAM 240
+ +++ A T+AGI+T++S + E + ++ + ++L +
Sbjct: 228 DNYYLRLSKEMQDSMARANEAAGETVAGIRTVRSFNTERSEAGRYDHRLMDTHNLKTRRD 287
Query: 241 KITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
+ A+Y L + M YYG I + ++ G L++ Y + + L +
Sbjct: 288 TVRAVYLLLKRLTALVMQVAMLYYGRLFIQRGQMSTGNLLSLTLYHSNLGANIGTLIYIF 347
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKGV 358
GD+ S+ AA ++F+ +D P+ + ++ G + F ++ +Y T GR VL+G
Sbjct: 348 GDMLNSVGAAGKVFEYLDREPQ-VSTKGTLQPETLTGHVHFHNLSFSYPTRQGRKVLQGF 406
Query: 359 SFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYV 418
S +++PG+ + GP G GKS+ + L+ RFY+P +GE+L+DG + + L + VA V
Sbjct: 407 SLELRPGQLTALVGPSGGGKSTCVSLLERFYQPQQGEILLDGQPLHSYQHHYLHRKVAMV 466
Query: 419 PQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSG 478
QEP +F+ SI++NIA + + E V+ AA+ A H FI+ L KGYDT VGE+G +SG
Sbjct: 467 GQEPVLFSGSIKDNIAYGLADCSLERVQEAARRANAHSFISQLEKGYDTDVGERGGQMSG 526
Query: 479 GQRQRIALARAMLMNPKIVLLDDPVSNL 506
G++QRIA+ARA++ P++++LD+ S L
Sbjct: 527 GEKQRIAIARALIREPQVLILDEVTSAL 554
>emb|CAA94219.2| (Z70268) Similarity to C.elegans p-glycoprotein (SW:MDR1_CAEEL),
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=388.5, E-value=2.1e-113, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=191.4, E-value=4.7e-54, N=2 [Caen>
Length = 1269
Score = 231 bits (582), Expect = 2e-59
Identities = 159/569 (27%), Positives = 293/569 (50%), Gaps = 26/569 (4%)
Query: 20 VHFLIGLFLIILMSYTNSIV-----PVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNG 74
V + +G +L++ TN+I P ++ A ++ G Y+V + + L G
Sbjct: 60 VSYTLGETAQVLVTITNAINNKTIDPADLKKAYEQ-YERGMYQVVLYF----FLCGCAYF 114
Query: 75 VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFL 134
F+ ++ Y +R + R + E+FD +G L + + ++ ER
Sbjct: 115 TFASIQHAIMKYVGDNTTYRVRKQYISRLLRKDAEYFDNVSTGHLSTVLNDNLERFREVF 174
Query: 135 SFRVRML--LYSIFLIIISLYYMVRMNITLTMVAL-ITIAIVVGLNTTYAMKVRPIYDKI 191
+ ++ ++ L + F++ +L + + + + IA +N+ MK +
Sbjct: 175 NEKIALIFALLTDFVVGTALAFYTDWRLASYGIFFSLGIAFSGFINSAGVMKTTGKQNTH 234
Query: 192 RHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE--ELYSLNVKAMKITALYGNA 249
G SIA T+ KT+ SL+ + ++++E + E Y ++ +A+ + G
Sbjct: 235 YANAG---SIAFQTLGAYKTVCSLNGQNTEIERYTEELKAGEKYGIH-RALMYSISRGFT 290
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
F L + + Y G I +L +V YM+ + L I + ++++
Sbjct: 291 YFFCNSLN-TVILYVGANMIYSGSLEPAVVVRIFHYMMFGAFCLSEALPHISRLAGAISS 349
Query: 310 ASRLFDVIDSAPKSIDPPDA---VEISNPRGEIEFRDVWLTYHT--GRTVLKGVSFKVKP 364
+ + +++ I+ + VE+ G I F++V +Y T VLKG+SF V+
Sbjct: 350 TAPIAEMLIKEDNVIEKDETDYDVEVE-VNGNISFKNVKFSYPTRPDAQVLKGISFDVQN 408
Query: 365 GEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI 424
GE + + G GSGKS++++L+ +Y G + IDG+++ + + LR+++ V QEP +
Sbjct: 409 GECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGMDLNDMNIKRLRRVIGVVSQEPVL 468
Query: 425 FNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRI 484
FN +I ENI PN + E+ A + A +DF+ S PKG T+VGE+G LSGGQ+QRI
Sbjct: 469 FNTTIEENIRFGNPNVSLPEIYGALRKANAYDFVCSFPKGIKTIVGERGTQLSGGQKQRI 528
Query: 485 ALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVI 544
A+AR ++ NPKI+LLD+ S LD E+E+ + + L+ Q +T ++V+ RLS ++ ++I
Sbjct: 529 AIARTLVRNPKILLLDEATSALDNESEQVVQKALENASQGRTTIVVAHRLSTIRNASKII 588
Query: 545 VMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
VM+ G+IVE G +ELI K G+++++++A
Sbjct: 589 VMQKGEIVEVGNHDELIAKRGVYNDLVQA 617
Score = 193 bits (485), Expect = 5e-48
Identities = 142/529 (26%), Positives = 255/529 (47%), Gaps = 17/529 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKT--FSGQL 119
+ L + + V + Y K ++ LR+ +F + F+D + +L
Sbjct: 737 WALSFMFLAVFRPLTLYCQYYYFGKVSEQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRL 796
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R+ D+ + + R+ ++ ++ I I++ +T+ LI ++
Sbjct: 797 SNRLNTDSSNVKAAVDDRLGCVIMTVVAISIAITTASLYCWKMTLEVLIFFPLLYLAEYC 856
Query: 180 Y--AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
Y A + D I + +I + ++T+++L++E+ + + S+ ++++
Sbjct: 857 YDAATETSIQEDTIAFENSNRTAIEA--LENMRTVRALNLEDKIMSLISEHLQKIHKSYF 914
Query: 238 KAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFL-TYMLTMMWPLRAL 296
K I S F +G ++ + + L T +T A
Sbjct: 915 KRAIIQGAANGLSLSCYLFVYSVSFKFGTYLALRKEVAPMDTYLILETLSMTANMAGSAA 974
Query: 297 GFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTV 354
+ + D ++++ AA +F + + + +GEI +V Y R +
Sbjct: 975 AY-LPDYKKAVHAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHYDQRPDRMI 1033
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVL------IDGVNVAKIKT 408
L GV+ KV PG+ + + GP G GKS+I+ L+ RFY GEV+ ID NV I
Sbjct: 1034 LNGVNLKVDPGKTLALVGPSGCGKSTIISLLERFYHAVDGEVVSIDAHKIDSENVEDINL 1093
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT-QEEVERAAKIAKIHDFIASLPKGYDT 467
+LR +A V QEP +FN SIREN+ + Q E+E+A + A +F+ P+G DT
Sbjct: 1094 NHLRSNLALVSQEPTLFNCSIRENLLYGLTRSVPQLELEKALQTANAFNFVFQFPQGLDT 1153
Query: 468 VVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTA 527
+VGE+G LSGGQ+QRIA+ARA+L NPK++LLD+ S LD+++EK + L + +
Sbjct: 1154 IVGERGAQLSGGQKQRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLST 1213
Query: 528 LIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
++V+ RL V D + V+K+GK+ E G EEL++K I+ +++ G+
Sbjct: 1214 VVVAHRLLTVVNADSIAVLKNGKVAEQGTHEELLRKRSIYWRLVQKQGI 1262
>pir||T25082 hypothetical protein T21E8.2 - Caenorhabditis elegans
Length = 1158
Score = 231 bits (582), Expect = 2e-59
Identities = 159/569 (27%), Positives = 293/569 (50%), Gaps = 26/569 (4%)
Query: 20 VHFLIGLFLIILMSYTNSIV-----PVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNG 74
V + +G +L++ TN+I P ++ A ++ G Y+V + + L G
Sbjct: 60 VSYTLGETAQVLVTITNAINNKTIDPADLKKAYEQ-YERGMYQVVLYF----FLCGCAYF 114
Query: 75 VFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFL 134
F+ ++ Y +R + R + E+FD +G L + + ++ ER
Sbjct: 115 TFASIQHAIMKYVGDNTTYRVRKQYISRLLRKDAEYFDNVSTGHLSTVLNDNLERFREVF 174
Query: 135 SFRVRML--LYSIFLIIISLYYMVRMNITLTMVAL-ITIAIVVGLNTTYAMKVRPIYDKI 191
+ ++ ++ L + F++ +L + + + + IA +N+ MK +
Sbjct: 175 NEKIALIFALLTDFVVGTALAFYTDWRLASYGIFFSLGIAFSGFINSAGVMKTTGKQNTH 234
Query: 192 RHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENE--ELYSLNVKAMKITALYGNA 249
G SIA T+ KT+ SL+ + ++++E + E Y ++ +A+ + G
Sbjct: 235 YANAG---SIAFQTLGAYKTVCSLNGQNTEIERYTEELKAGEKYGIH-RALMYSISRGFT 290
Query: 250 PFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAA 309
F L + + Y G I +L +V YM+ + L I + ++++
Sbjct: 291 YFFCNSLN-TVILYVGANMIYSGSLEPAVVVRIFHYMMFGAFCLSEALPHISRLAGAISS 349
Query: 310 ASRLFDVIDSAPKSIDPPDA---VEISNPRGEIEFRDVWLTYHT--GRTVLKGVSFKVKP 364
+ + +++ I+ + VE+ G I F++V +Y T VLKG+SF V+
Sbjct: 350 TAPIAEMLIKEDNVIEKDETDYDVEVE-VNGNISFKNVKFSYPTRPDAQVLKGISFDVQN 408
Query: 365 GEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI 424
GE + + G GSGKS++++L+ +Y G + IDG+++ + + LR+++ V QEP +
Sbjct: 409 GECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGMDLNDMNIKRLRRVIGVVSQEPVL 468
Query: 425 FNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRI 484
FN +I ENI PN + E+ A + A +DF+ S PKG T+VGE+G LSGGQ+QRI
Sbjct: 469 FNTTIEENIRFGNPNVSLPEIYGALRKANAYDFVCSFPKGIKTIVGERGTQLSGGQKQRI 528
Query: 485 ALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVI 544
A+AR ++ NPKI+LLD+ S LD E+E+ + + L+ Q +T ++V+ RLS ++ ++I
Sbjct: 529 AIARTLVRNPKILLLDEATSALDNESEQVVQKALENASQGRTTIVVAHRLSTIRNASKII 588
Query: 545 VMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
VM+ G+IVE G +ELI K G+++++++A
Sbjct: 589 VMQKGEIVEVGNHDELIAKRGVYNDLVQA 617
Score = 96.0 bits (235), Expect = 1e-18
Identities = 93/416 (22%), Positives = 178/416 (42%), Gaps = 17/416 (4%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKT--FSGQL 119
+ L + + V + Y K ++ LR+ +F + F+D + +L
Sbjct: 737 WALSFMFLAVFRPLTLYCQYYYFGKVSEQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRL 796
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTT 179
+R+ D+ + + R+ ++ ++ I I++ +T+ LI ++
Sbjct: 797 SNRLNTDSSNVKAAVDDRLGCVIMTVVAISIAITTASLYCWKMTLEVLIFFPLLYLAEYC 856
Query: 180 Y--AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
Y A + D I + +I + ++T+++L++E+ + + S+ ++++
Sbjct: 857 YDAATETSIQEDTIAFENSNRTAIEA--LENMRTVRALNLEDKIMSLISEHLQKIHKSYF 914
Query: 238 KAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFL-TYMLTMMWPLRAL 296
K I S F +G ++ + + L T +T A
Sbjct: 915 KRAIIQGAANGLSLSCYLFVYSVSFKFGTYLALRKEVAPMDTYLILETLSMTANMAGSAA 974
Query: 297 GFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY--HTGRTV 354
+ + D ++++ AA +F + + + +GEI +V Y R +
Sbjct: 975 AY-LPDYKKAVHAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHYDQRPDRMI 1033
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVL------IDGVNVAKIKT 408
L GV+ KV PG+ + + GP G GKS+I+ L+ RFY GEV+ ID NV I
Sbjct: 1034 LNGVNLKVDPGKTLALVGPSGCGKSTIISLLERFYHAVDGEVVSIDAHKIDSENVEDINL 1093
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT-QEEVERAAKIAKIHDFIASLPK 463
+LR +A V QEP +FN SIREN+ + Q E+E+A + A +F+ P+
Sbjct: 1094 NHLRSNLALVSQEPTLFNCSIRENLLYGLTRSVPQLELEKALQTANAFNFVFQFPQ 1149
>dbj|BAB02613.1| (AP002043) P-glycoprotein; multi-drug resistance related; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1241
Score = 230 bits (581), Expect = 3e-59
Identities = 149/521 (28%), Positives = 271/521 (51%), Gaps = 12/521 (2%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
Y L+ + + L+ +L Y K + + LR+ I E +FD + F+ ++
Sbjct: 719 YSLIFISLTFLSITLNLLQHYSFAKMGERLMQRLRLKMLEKIFTFEPAWFDVEENFTSEI 778
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY--MVRMNITLTMVALITIAIVVGLN 177
SR+ N+ + ++ R+ +L+ +I + I++ ++ + L M+A+ ++I+
Sbjct: 779 CSRLNNEVSIVKSLVADRISLLVQTISGVTIAMIIGLLISWKLALVMIAVQPLSILCFYT 838
Query: 178 TTYAM-KVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLN 236
+ K+ Y ++++ IAS A I K + SL + + F E
Sbjct: 839 KKVLLSKISNNYAYAQNRSSQIASEA---IYNHKIVTSLGSTKKIIEIFDNAQYEAKRKG 895
Query: 237 VKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRAL 296
KA + + + L + F+YGG + + ++ G++ +++ +
Sbjct: 896 RKAAWLAGFGMGSAQCLTFLTWALDFWYGGVLVQKGEISAGDVFKTFFVLVSTGKVIAEA 955
Query: 297 GFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRT--V 354
G D+ + AA S +F+++D + ++ +G IE +++ +Y + V
Sbjct: 956 GSMTSDLAKGTAAISSVFNILDRPSSHENTNHGEKMGTIQGRIELKNIDFSYPNRPSILV 1015
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
L+ S +KPG + + G G GKS+++ LI RFY G V ID N+ I + RK
Sbjct: 1016 LRDFSLDIKPGTSIGLVGTSGCGKSTVIALIQRFYDVEIGCVKIDSENLRDINIKWYRKH 1075
Query: 415 VAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGI 474
A V QEP +++ SI++NI L +P AT++EV AAK A HDFI+++ KGY T GE+G+
Sbjct: 1076 TALVSQEPVVYSGSIQDNIILGRPEATEDEVVEAAKAANAHDFISAMEKGYKTECGERGV 1135
Query: 475 TLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEIL--QDKTALIVSQ 532
LSGGQ+QRIA+ARA L +P I+LLD+ S+LD+ +E+++ + L I+ ++ T ++V+
Sbjct: 1136 QLSGGQKQRIAIARAFLRSPIILLLDEVTSSLDSNSEQEVQDALARIMASRNMTTVVVAH 1195
Query: 533 RLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
RL+ +K +D + ++ DG ++E G + L GG FS + A
Sbjct: 1196 RLNTLKNLDCIALIVDGTVIETGSYDHLKNIGGQFSRLAHA 1236
Score = 228 bits (575), Expect = 1e-58
Identities = 163/533 (30%), Positives = 273/533 (50%), Gaps = 36/533 (6%)
Query: 63 GLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS-GQLIS 121
GL IL V + G Y K ++ V +R A+ R E+ FFD S ++I
Sbjct: 88 GLAILGVAFMEG-------YCWSKTSERQVMKIRRTYLEAVLRQEVSFFDSDISTSEIIH 140
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
I+ DT I + LS +V + L I + I L + + LT+VA+ T+ +++ Y
Sbjct: 141 TISTDTSLIQQLLSEKVPIFLMHISVFITGLVFSAYFSWRLTVVAIPTLVLLLIPGLIYG 200
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ + K + SI ++ IKTI S + E + K+S+ E L +K
Sbjct: 201 KYLVHLSKKSFKEYTKANSIVEQALSSIKTILSFTAETQIIKKYSEVLERHKKLGLKQ-- 258
Query: 242 ITALYGNAPFLVLGLA------MSTMFYYGGKAIIQNTLTVGELVAF-LTYMLTMMWPLR 294
G A L +G + + + +YG + ++ T G + A ++++L +
Sbjct: 259 -----GLAKGLAVGSSGISFTIWAFLAWYGSRLVMHKQETGGRIYAAGISFVLGGI---- 309
Query: 295 ALGFTIGDIQ---RSLAAASRLFDVIDSAPKSIDPPDAVEISNP----RGEIEFRDVWLT 347
+LG + +I+ + AA+R+ ID + ID D + P +G +EF V L
Sbjct: 310 SLGTALTEIRYFSEASVAAARICSRIDRISE-IDGEDTKKGFIPGEKMKGRVEFERVTLV 368
Query: 348 Y--HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAK 405
Y +LK + V G+ V + G GSGKS+++ L+ RFY P +G V IDG ++
Sbjct: 369 YLSRPETIILKDFTLTVDVGQSVALMGASGSGKSTVIALLQRFYDPCEGFVRIDGFDIKT 428
Query: 406 IKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGY 465
++ + +R+ + V Q+ +F SI EN+ K A+ +EV AAK A H FI LP GY
Sbjct: 429 LQLKWMRQHIGVVSQDHALFGTSIMENLMFGKNKASMDEVISAAKAANAHGFITQLPNGY 488
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
DT +G +G LSGGQ+QRIA+ARA++ NP I+LLD+ S LD E+E + L ++ +
Sbjct: 489 DTHIGNRGALLSGGQKQRIAIARAIIRNPVILLLDEATSALDGESETLIQNALDQVAAGR 548
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGVYG 578
T L+V+ +LS V+ + + ++++G + E G E+L+ K +++++K +G
Sbjct: 549 TTLVVAHKLSTVRGANIIAMLENGSVRELGSHEDLMTKNNHYAKLVKLQRQFG 601
>pir||T22094 hypothetical protein ZK455.7 - Caenorhabditis elegans
>gi|3877009|emb|CAA91467.1| (Z66562) multidrug resistance
protein 3 (p-glycoprotein C), contains similarity to Pfam
domain: PF00005 (ABC transporter), Score=417.1,
E-value=5.3e-122, N=2; PF00664 (ABC transporter
transmembrane region.), Score=489.5, E-value=8.5e-144,
N=2~cDNA EST > >gi|3881645|emb|CAA91495.1| (Z66567)
multidrug resistance protein 3 (p-glycoprotein C),
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=417.1, E-value=5.3e-122, N=2; PF00664
(ABC transporter transmembrane region.), Score=489.5,
E-value=8.5e-144, N=2~cDNA EST >
Length = 1268
Score = 229 bits (579), Expect = 5e-59
Identities = 171/586 (29%), Positives = 293/586 (49%), Gaps = 36/586 (6%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY---GL 64
L + Y + +I L ++ +T + + + K +S G V+I+ L
Sbjct: 694 LFDIFKYASPEMRNIIISLVFTLIRGFTWPAFSI-VYGQLFKILSAGGDDVSIKALLNSL 752
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS--GQLISR 122
+L+ G+ +L LL KA + LRMD FR I + + +FD + G L SR
Sbjct: 753 WFILLAFTGGISTLISGSLLGKAGETMSGRLRMDVFRNIMQQDASYFDDSRHNVGSLTSR 812
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
+ D + + R+ +L I + + + + L T ++V + ++ A
Sbjct: 813 LATDAPNVQAAIDQRLAEVLTGIVSLFCGVGVAFYYGWNMAPIGLATALLLVVVQSSVAQ 872
Query: 183 KVRPIYDKIRHQTGVIASI-----ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
Y K R Q + ++I T +I+ KT+++L+ +E + F+ ++ + +
Sbjct: 873 -----YLKFRGQRDMDSAIEASRLVTESISNWKTVQALTKQEYMYDAFTAASKSPHRRAI 927
Query: 238 KAMKITALYGNAPFLVLGLAMSTMF---YYGGKAIIQNT----LTVGELVAFLTYMLTMM 290
+ L+ + F + G + F Y G +I N TV +++ L M +M
Sbjct: 928 ----VRGLWQSLSFALAGSFVMWNFAIAYMFGLWLISNNWSTPYTVFQVIEALN-MASMS 982
Query: 291 WPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP--RGEIEFRDVWLTY 348
L A F + R+ +A +F +I KS+ + P +G I R V+ Y
Sbjct: 983 VMLAASYFP--EYVRARISAGIMFTMIRQ--KSVIDNRGLTGDTPTIKGNINMRGVYFAY 1038
Query: 349 HTGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
R VL G + G+ V + GP G GKS+ ++LI R+Y G V ID ++ +
Sbjct: 1039 PNRRRQLVLDGFNMSANFGQTVALVGPSGCGKSTTIQLIERYYDALCGSVKIDDSDIRDL 1098
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
++LR +A V QEP +FN +IRENI N TQ++VE+AA +A IH F+ LP GYD
Sbjct: 1099 SVKHLRDNIALVGQEPTLFNLTIRENITYGLENITQDQVEKAATLANIHTFVMGLPDGYD 1158
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T VG G LSGGQ+QR+A+ARA++ +PKI+LLD+ S LD E+EK + E L + +T
Sbjct: 1159 TSVGASGGRLSGGQKQRVAIARAIVRDPKILLLDEATSALDTESEKIVQEALDKARLGRT 1218
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
++++ RLS ++ D++IV ++GK +E+G + L+ + G++ +++
Sbjct: 1219 CVVIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRGLYYRLVE 1264
Score = 227 bits (572), Expect = 3e-58
Identities = 145/509 (28%), Positives = 254/509 (49%), Gaps = 4/509 (0%)
Query: 69 VGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTE 128
+GV + S L + ++ +R +++ R + ++FD+T G L ++++ E
Sbjct: 105 LGVALFLCSYFANSCLYTLCERRLHCIRKKYLKSVLRQDAKWFDETTIGGLTQKMSSGIE 164
Query: 129 RITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
+I + +V +L+ + I + M LT+V +IT+ + +G A +
Sbjct: 165 KIKDGIGDKVGVLVGGVATFISGVSIGFYMCWQLTLVMMITVPLQLGSMYLSAKHLNRAT 224
Query: 189 DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGN 248
+A IAGI+T+ + + + +++ + E + ++ I A+
Sbjct: 225 KNEMSAYSNAGGMANEVIAGIRTVMAFNAQPFEINRYAHQLNEARRMGIRKAIILAICTA 284
Query: 249 APFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLA 308
P +++ M+ F+YG ++ G + A +L L +G I +
Sbjct: 285 FPLMLMFTCMAVAFWYGATLAAAGAVSSGAVFAVFWAVLIGTRRLGEAAPHLGAITGARL 344
Query: 309 AASRLFDVIDSAPKSIDPPDAVEISNP-RGEIEFRDVWLTYHTGRT--VLKGVSFKVKPG 365
A +F VID P+ +I +G++ F + TY T +LKGVSF+V PG
Sbjct: 345 AIHDIFKVIDHEPEIKCTSSEGKIPEKIQGKLTFDGIEFTYPTRPELKILKGVSFEVNPG 404
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
E V + G G GKS+ + L+ RFY G + +DG+ + + LR + V QEP IF
Sbjct: 405 ETVALVGHSGCGKSTSIGLLMRFYNQCAGMIKLDGIPIQEYNIRWLRSTIGIVQQEPIIF 464
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
++ ENI + T +++E A K+A H+FI L YDTV+G + LSGGQ+QR+A
Sbjct: 465 VATVAENIRMGDVLITDQDIEEACKMANAHEFICKLSDRYDTVIGAGAVQLSGGQKQRVA 524
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+ARA++ P+I+LLD+ S LD E+E+ + L + + +T L ++ RLS ++ +++V
Sbjct: 525 IARAIVRKPQILLLDEATSALDTESERMVQTALDKASEGRTTLCIAHRLSTIRNASKILV 584
Query: 546 MKDGKIVEDGKPEELIKK-GGIFSEMMKA 573
G I E G +ELI K GI++ M+KA
Sbjct: 585 FDQGLIAERGTHDELISKDDGIYASMVKA 613
>sp|P34713|MDR3_CAEEL MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN C)
>gi|283552|pir||S27338 P-glycoprotein C - Caenorhabditis
elegans >gi|6811|emb|CAA46191.1| (X65055) P-glycoprotein
C [Caenorhabditis elegans]
Length = 1254
Score = 229 bits (577), Expect = 8e-59
Identities = 171/586 (29%), Positives = 293/586 (49%), Gaps = 36/586 (6%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRY---GL 64
L + Y + +I L ++ +T + + + K +S G V+I+ L
Sbjct: 680 LFDIFKYASPEMRNIIISLVFTLIRGFTWPAFSI-VYGQLFKILSAGGDDVSIKALLNSL 738
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS--GQLISR 122
+L+ G+ +L LL KA + LRMD FR I + + +FD + G L SR
Sbjct: 739 WFILLAFTGGISTLISGSLLGKAGETMSGRLRMDVFRNIMQQDASYFDDSRHNVGSLTSR 798
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
+ D + + R+ +L I + + + + L T ++V + ++ A
Sbjct: 799 LATDAPNVQAAIDQRLAEVLTGIVSLFCGVGVAFYYGWNMAPIGLATELLLVVVQSSVAQ 858
Query: 183 KVRPIYDKIRHQTGVIASI-----ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV 237
Y K R Q + ++I T +I+ KT+++L+ +E + F+ ++ + +
Sbjct: 859 -----YLKFRGQRDMDSAIEASRLVTESISNWKTVQALTKQEYMYDAFTAASKSPHRRAI 913
Query: 238 KAMKITALYGNAPFLVLGLAMSTMF---YYGGKAIIQNT----LTVGELVAFLTYMLTMM 290
+ L+ + F + G + F Y G +I N TV +++ L M +M
Sbjct: 914 ----VRGLWQSLSFALAGSFVMWNFAIAYMFGLWLISNNWSTPYTVFQVIEALN-MASMS 968
Query: 291 WPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP--RGEIEFRDVWLTY 348
L A F + R+ +A +F +I KS+ + P +G I R V+ Y
Sbjct: 969 VMLAASYFP--EYVRARISAGIMFTMIRQ--KSVIDNRGLTGDTPTIKGNINMRGVYFAY 1024
Query: 349 HTGRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
R VL G + G+ V + GP G GKS+ ++LI R+Y G V ID ++ +
Sbjct: 1025 PNRRRQLVLDGFNMSANFGQTVALVGPSGCGKSTTIQLIERYYDALCGSVKIDDSDIRDL 1084
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYD 466
++LR +A V QEP +FN +IRENI N TQ++VE+AA +A IH F+ LP GYD
Sbjct: 1085 SVKHLRDNIALVGQEPTLFNLTIRENITYGLENITQDQVEKAATLANIHTFVMGLPDGYD 1144
Query: 467 TVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKT 526
T VG G LSGGQ+QR+A+ARA++ +PKI+LLD+ S LD E+EK + E L + +T
Sbjct: 1145 TSVGASGGRLSGGQKQRVAIARAIVRDPKILLLDEATSALDTESEKIVQEALDKARLGRT 1204
Query: 527 ALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
++++ RLS ++ D++IV ++GK +E+G + L+ + G++ +++
Sbjct: 1205 CVVIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRGLYYRLVE 1250
Score = 207 bits (521), Expect = 3e-52
Identities = 140/509 (27%), Positives = 246/509 (47%), Gaps = 18/509 (3%)
Query: 69 VGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTE 128
+GV + S L + ++ +R +++ R + ++FD+T G L ++++ E
Sbjct: 105 LGVALFLCSYFANSCLYTLCERRLHCIRKKYLKSVLRQDAKWFDETTIGGLTQKMSSGIE 164
Query: 129 RITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
+I + +V +L+ + I + M LT+V +IT+ + +G A +
Sbjct: 165 KIKDGIGDKVGVLVGGVATFISGVSIGFYMCWQLTLVMMITVPLQLGSMYLSAKHLNRAT 224
Query: 189 DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGN 248
+A IAGI+T+ + + + +++ + E + ++ I A+
Sbjct: 225 KNEMSAYSNAGGMANEVIAGIRTVMAFNAQPFEINRYAHQLNEARRMGIRKAIILAICTA 284
Query: 249 APFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLA 308
P +++ M+ F+YG ++ G + A +L L +G I +
Sbjct: 285 FPLMLMFTCMAVAFWYGATLAAAGAVSSGAVFAVFWAVLIGTRRLGEAAPHLGAITGARL 344
Query: 309 AASRLFDVIDSAPKSIDPPDAVEISNP-RGEIEFRDVWLTYHTGRT--VLKGVSFKVKPG 365
A +F VID P+ +I +G++ F + TY T +LKGVSF+V PG
Sbjct: 345 AIHDIFKVIDHEPEIKCTSSEGKIPEKIQGKLTFDGIEFTYPTRPELKILKGVSFEVNPG 404
Query: 366 EKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIF 425
E V + G G GKS+ + L+ RFY G + +DG+ + + LR + V QEP IF
Sbjct: 405 ETVALVGHSGCGKSTSIGLLMRFYNQCAGMIKLDGIPIQEYNIRWLRSTIGIVQQEPIIF 464
Query: 426 NRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIA 485
++ ENI + T +++E A K+A H+FI L YDTV+G + LSGGQ+QR+A
Sbjct: 465 VATVAENIRMGDVLITDQDIEEACKMANAHEFICKLSDRYDTVIGAGAVQLSGGQKQRVA 524
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
+ARA++ P+I+LLD+ S LD E+E+ + L + + +T L ++ RLS ++
Sbjct: 525 IARAIVRKPQILLLDEATSALDTESERMVQTALDKASEGRTTLCIAHRLSTIR------- 577
Query: 546 MKDGKIVEDGKPEELIKK-GGIFSEMMKA 573
+ELI K GI++ M+KA
Sbjct: 578 -------NASTHDELISKDDGIYASMVKA 599
>sp|P36619|PMD1_SCHPO LEPTOMYCIN B RESISTANCE PROTEIN PMD1 >gi|101052|pir||S20548
leptomycin B resistance protein - fission yeast
(Schizosaccharomyces pombe) >gi|218550|dbj|BAA01537.1|
(D10695) pmd1 protein [Schizosaccharomyces pombe]
Length = 1362
Score = 229 bits (577), Expect = 8e-59
Identities = 165/531 (31%), Positives = 273/531 (51%), Gaps = 35/531 (6%)
Query: 67 LLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITND 126
L++ ++ + + A + + +R FR + R ++EFFD++ N
Sbjct: 843 LILAIVQFFAYAISNFAMTYAMEAVLQRIRYHLFRTLLRQDVEFFDRS---------ENT 893
Query: 127 TERITRFLSFRVRML-------LYSIFLIIISLYYMVRMNIT----LTMVALITIAIVVG 175
IT LS +++ L L + F I+ ++ + +++ L +V L T +++
Sbjct: 894 VGAITTSLSTKIQSLEGLSGPTLGTFFQILTNIISVTILSLATGWKLGLVTLSTSPVIIT 953
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ + +K+ A+ A + + I+T+ SL+ EENV ++ +
Sbjct: 954 AGYYRVRALDQVQEKLSAAYKESAAFACESTSAIRTVASLNREENVFAEYCDSLIKPGRE 1013
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
+ A + L+ +A V L + F+YG + + + V F T + +++ ++
Sbjct: 1014 SAIASLKSGLFFSAAQGVTFLINALTFWYGSTLMRKGEYNI---VQFYTCFIAIVFGIQQ 1070
Query: 296 LGFTIG---DIQRSLAAASRLFDVIDSAPKSIDPPDA----VEISNPRGEIEFRDVWLTY 348
G G D+ ++ AAA + + +S PK ID VE S IEFR V +Y
Sbjct: 1071 AGQFFGYSADVTKAKAAAGEIKYLSESKPK-IDTWSTEGKKVE-SLQSAAIEFRQVEFSY 1128
Query: 349 HTGR--TVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
T R VL+G++ VKPG+ V G G GKS+ + LI RFY G VL+DGVNV
Sbjct: 1129 PTRRHIKVLRGLNLTVKPGQFVAFVGSSGCGKSTTIGLIERFYDCDNGAVLVDGVNVRDY 1188
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGY 465
+ RK +A V QEP ++ ++RENI L A + ++EE+ A K A IH+FI LP GY
Sbjct: 1189 NINDYRKQIALVSQEPTLYQGTVRENIVLGASKDVSEEEMIEACKKANIHEFILGLPNGY 1248
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
+T+ G+KG +LSGGQ+QRIA+ARA++ NPKI+LLD+ S LD+ +EK + E L Q +
Sbjct: 1249 NTLCGQKGSSLSGGQKQRIAIARALIRNPKILLLDEATSALDSHSEKVVQEALNAASQGR 1308
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
T + ++ RLS ++ D + V G E G EL+K+ G + E++ G+
Sbjct: 1309 TTVAIAHRLSSIQDADCIFVFDGGVTCEAGTHAELVKQRGRYYELVVEQGL 1359
Score = 218 bits (550), Expect = 1e-55
Identities = 169/611 (27%), Positives = 300/611 (48%), Gaps = 62/611 (10%)
Query: 10 RLLSY---------LRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAI 60
R+LSY L G GL + ++ + + A KG S+ + V
Sbjct: 82 RILSYADKWDIMLQLAGTITGIGAGLGMPLMSLVSGQLAQAFTDLASGKGASSFQHTVD- 140
Query: 61 RYGLLILLVGVLNGVFSLAGRYLL--VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQ 118
+ L + + + GVF + Y + + A + +R D AI + +FD+ +G+
Sbjct: 141 HFCLYFIYIAI--GVFGCSYIYTVTFIIAGERIARRIRQDYLHAILSQNIGYFDRLGAGE 198
Query: 119 LISRITNDTERITRFLSFRVRMLLYSI--FLIIISLYYMVRMNITLTMVALI-TIAIVVG 175
+ +RIT DT I L +V ++ ++I F+ + ++ TL + ++ I +G
Sbjct: 199 ITTRITTDTNFIQDGLGEKVGLVFFAIATFVSGFVIAFIRHWKFTLILSSMFPAICGGIG 258
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEE---NVQTKFSQENEEL 232
L + K + G IA +A S VEE N++ F+ +++
Sbjct: 259 LGVPFITK---------NTKGQIAVVAES---------STFVEEVFSNIRNAFAFGTQDI 300
Query: 233 YSLNVKAMKITAL-YGNAPFLVLGLAMSTMFYY-----------GGKAIIQNTLTVGELV 280
+ ITA +G + +GL + MF+ GG+ + L V +L+
Sbjct: 301 LAKLYNKYLITAQRFGINKAIAMGLMVGWMFFVAYGVYGLAFWEGGRLLHAGDLDVSKLI 360
Query: 281 AFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDS-APKSIDPPDAVEISNPRGEI 339
+L + L + + +AA ++FD ID +P + P + + +GEI
Sbjct: 361 GCFFAVLIASYSLANISPKMQSFVSCASAAKKIFDTIDRVSPINAFTPTGDVVKDIKGEI 420
Query: 340 EFRDVWLTYHTGRTVLKGVSFKV--KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVL 397
E +++ Y T VL +F + G+ + G GSGKS+I+ L+ RFY P G+V
Sbjct: 421 ELKNIRFVYPTRPEVLVLDNFSLVCPSGKITALVGASGSGKSTIIGLVERFYDPIGGQVF 480
Query: 398 IDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNA-----TQEEVER----A 448
+DG ++ + +LR ++ V QEP +F ++ ENI P+ ++EE+ER A
Sbjct: 481 LDGKDLRTLNVASLRNQISLVQQEPVLFATTVFENITYGLPDTIKGTLSKEELERRVYDA 540
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
AK+A +DFI +LP+ + T VG++G +SGGQ+QRIA+ARA++ +PKI+LLD+ S LD+
Sbjct: 541 AKLANAYDFIMTLPEQFSTNVGQRGFLMSGGQKQRIAIARAVISDPKILLLDEATSALDS 600
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFS 568
++E + + L + +T ++++ RLS ++ D ++V+ GKIVE G EL+ G ++
Sbjct: 601 KSEVLVQKALDNASRSRTTIVIAHRLSTIRNADNIVVVNAGKIVEQGSHNELLDLNGAYA 660
Query: 569 EMMKAGGVYGG 579
+++A + GG
Sbjct: 661 RLVEAQKLSGG 671
>gb|AAB37564.1| (U40139) ComA [Streptococcus gordonii]
Length = 532
Score = 229 bits (577), Expect = 8e-59
Identities = 145/520 (27%), Positives = 277/520 (52%), Gaps = 26/520 (5%)
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+++V +L S A YLL+ Q + + + + + M FF +G+++SR T
Sbjct: 27 LIIVYILQQFLSYAQEYLLLVLGQRLSIDVILSYIKHVFQLPMSFFATRRTGEIVSRFT- 85
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
D RI L+ + + + ++ I + N +L + L+ I + + + ++
Sbjct: 86 DANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYALIIFLF---MK 142
Query: 186 PIYDKIRHQT----GVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
P ++K+ H+T +++S I GI+TIKSL+ E+ K +E V +K
Sbjct: 143 P-FEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEF-------VTYLK 194
Query: 242 ITALYGNAPFLVLGLAMST-------MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
+ YG + L L + + + G ++ +++G+L+ + T ++ PL
Sbjct: 195 KSFAYGRSESLQKVLKAAARLILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLE 254
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+ +Q + A RL +V + + ++S+ + +I+FR V Y G V
Sbjct: 255 NIINLQTKLQSARVANERLNEVYLVKSEFEEKKLIKDLSHFQADIDFRGVSYKYGYGANV 314
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
L + + G K G GSGK+++ K++ FY P +G++ + GVN+ ++ + LR+
Sbjct: 315 LSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYAPNQGDICLGGVNLNQLDKQALRQY 374
Query: 415 VAYVPQEPFIFNRSIRENIAL-AKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKG 473
+ Y+PQ+P++FN +I EN+ L A+ TQE++ RA ++A+I I +P Y T + G
Sbjct: 375 INYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADG 434
Query: 474 ITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQR 533
+SGGQRQRIALARA+L + +++LD+ S+LD TEK+++++L ++ DKT + ++ R
Sbjct: 435 AGISGGQRQRIALARALLTDAPVLILDEATSSLDILTEKRIIDNL--MVLDKTIIFIAHR 492
Query: 534 LSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
L++ + ++V+V+ G+IVE G +ELI++ G + ++ +
Sbjct: 493 LTIAERSEQVVVLDQGRIVESGSHKELIEREGFYHHLVNS 532
>pir||T18939 hypothetical protein C05A9.1 - Caenorhabditis elegans
>gi|3874030|emb|CAA94202.1| (Z70265) Similarity to
C.elegans p-glycoprotein (SW:MDR1_CAEEL), contains
similarity to Pfam domain: PF00005 (ABC transporter),
Score=413.1, E-value=8.4e-121, N=2; PF00664 (ABC
transporter transmembrane region.), Score=192.1,
E-value=2.9e-54, N=2~cDNA >
Length = 1283
Score = 227 bits (573), Expect = 2e-58
Identities = 160/555 (28%), Positives = 280/555 (49%), Gaps = 21/555 (3%)
Query: 30 ILMSYTNSIVPVLIRNAIDKGVSTGAYKV----AIRYGLLILLVGVLNGVFSLAGRYLLV 85
+L+ TN+I ID AYK+ R LL LVG F ++
Sbjct: 95 VLVKVTNAIN----NKTIDPVDLAHAYKLFESDMNRVVLLFFLVGFAYFTFGFLQFSIMK 150
Query: 86 KAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSI 145
Y +R + R ++ +FD +G L + ++ ER + ++ +++ +
Sbjct: 151 FVGDNTAYNVRRQYISRLLRKDISYFDGMSTGHLSIVLNDNMERFREVFNEKIALIIALL 210
Query: 146 FLIIISLYYMVRMNITLTMVALI-TIAIVVG--LNTTYAMKVRPIYDKIRHQTGVIASIA 202
+I + L + + IV+ L++ MK +K SIA
Sbjct: 211 TDFVIGTILAFYTDWRLACYGTVFSFGIVLSGLLDSWGKMKNN---EKQNEHISNAGSIA 267
Query: 203 TGTIAGIKTIKSLSVEENVQTKFSQE--NEELYSLNVKAMKITALYGNAPFLVLGLAMST 260
+ KT+ SL+ ++ ++++E N E Y+LN + +L +A +
Sbjct: 268 FQALGCYKTVSSLNGQQQEVERYTEELKNGEKYALN--RAFVFSLSRSADYFFTNALNFV 325
Query: 261 MFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSA 320
+ Y+G I + T+ G +V L Y+L + L I + ++ + D++ +
Sbjct: 326 ILYFGANMIYEGTIEPGVVVRILYYILFGSYCLGEAILHISRLASAIPLTVPIADILLDS 385
Query: 321 PKSIDPPDAVEISNP-RGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSG 377
+ D + EI + +G I F++V +Y T V LK +SF V+ GE + + G GSG
Sbjct: 386 DATADEFFSEEIKDTFQGIISFKNVLFSYPTRPDVPVLKEISFNVQGGECIALVGASGSG 445
Query: 378 KSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAK 437
KS++++L+ +Y G + IDG ++ I + LR+ + V QEP +FN SI ENI K
Sbjct: 446 KSTVIQLLLHYYNIDSGRISIDGNDIYNINIKQLRQAMGVVFQEPVLFNTSIEENIRFGK 505
Query: 438 PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
P+AT++E+ A K A DF+ + P G T+VGE+G LSGGQ+QRIA+AR ++ NP+I+
Sbjct: 506 PDATEQEIIDALKNANAFDFVCNFPDGIKTIVGERGAQLSGGQKQRIAIARTLVRNPRIL 565
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
LLD+ S LD E+E + E L++ +T ++V+ RLS ++ +++IVM+ G+IVE G
Sbjct: 566 LLDEATSALDNESEFIVQEALQKASIGRTTIVVAHRLSTIRNANKIIVMEKGEIVEVGDH 625
Query: 558 EELIKKGGIFSEMMK 572
++LI G+++ +++
Sbjct: 626 KQLIAMNGVYNNLVQ 640
Score = 219 bits (553), Expect = 5e-56
Identities = 154/527 (29%), Positives = 270/527 (51%), Gaps = 19/527 (3%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTF--SGQL 119
+ L IL + +F Y K A+ LR +F+ + F+D + +L
Sbjct: 757 WALSILFLAFTRPIFIFFQYYFFGKTAEKLSIKLRSMSFKHLMSLPCAFYDDPCHTATRL 816
Query: 120 ISRITNDTERITRFLSFR---VRMLLYSIFL-IIISLYYMVRMNITLTMVALITIAIVVG 175
+R+ D+ +T + R V M L +I L +I+S +Y +M++ + M + + G
Sbjct: 817 SNRLNADSSNVTAAVDDRLGSVIMTLVAILLAVIMSFFYSWKMSLQVLMFC--PLLYLAG 874
Query: 176 LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
+ D I + A+I + ++T+++L++E V + +++ +
Sbjct: 875 YCNDNFVDQAVEEDSIAFEKSNRAAIEA--LENVRTVRALNMENRVILLVTSHLQKIRNS 932
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAII-QNTLTVGELVAFLTYMLTMMWPLR 294
K I + F +G ++ + L + + +T +T +
Sbjct: 933 YFKRAVIQGTANGFACSCYFFIYAVSFKFGTWLVLREEILPMDTYLVLMTLSMTASYAGS 992
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISN--PRGEIEFRDVWLTY--HT 350
A+ + + D ++++ AA +F + +I P D+ + GEIE ++V Y +
Sbjct: 993 AVAY-LPDHRKAIHAAGLIFHLFTYP--AIMPYDSSQGKRNIKNGEIELKNVSFEYAQRS 1049
Query: 351 GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTEN 410
+ +L GVS K+ G + + GP GSGKS+I+ L+ RFY GEV ID NV + +
Sbjct: 1050 DKMILDGVSLKLPAGRTLALVGPSGSGKSTIISLLERFYHAVDGEVKIDEENVVDVNLHH 1109
Query: 411 LRKIVAYVPQEPFIFNRSIRENIALA-KPNATQEEVERAAKIAKIHDFIASLPKGYDTVV 469
LR+ V+ V QEP +FN SI+EN NA+Q E+++A K+A F++ P+G DT+V
Sbjct: 1110 LRESVSLVSQEPVLFNCSIKENFLFGISHNASQLEIDQALKVANAFSFVSQFPQGLDTLV 1169
Query: 470 GEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALI 529
GE+G LSGGQ+QRIA+ARA+L NPK++LLD+ S LD+++EK + L + + ++
Sbjct: 1170 GERGAQLSGGQKQRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVV 1229
Query: 530 VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
V+ RLS V D + V+K+GK+ E G EEL++K I+ +++ G+
Sbjct: 1230 VAHRLSTVVNADSIAVLKNGKVAEQGTHEELLRKRSIYWRLVQKQGI 1276
>pir||H82351 probable hemolysin secretion ATP-binding protein VC0199 [imported]
- Vibrio cholerae (group O1 strain N16961)
>gi|9654605|gb|AAF93375.1| (AE004110) hemolysin
secretion ATP-binding protein, putative [Vibrio
cholerae]
Length = 611
Score = 227 bits (572), Expect = 3e-58
Identities = 138/498 (27%), Positives = 249/498 (49%), Gaps = 21/498 (4%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
+R R + + + FF + F+G++ +++ + + + V + +Y ++ L
Sbjct: 119 IRWSTHRYLLKQSIGFFQRDFAGRVATKVMQNANSVRETVLKLVDLSVYIAVYMVSMLVM 178
Query: 155 MVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKS 214
+ + L + L+ + + + + +++ I + + T I T+K
Sbjct: 179 IAEADKILVVPILVWLLFYIAIQVYFVPRLKTISTDQANAQSQMTGRIVDTYTNITTVKL 238
Query: 215 LSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTL 274
S + T ++ + M+ + L+ L + ++ + + T+
Sbjct: 239 FSHSQRETTYAKSGMKQFLHTVYRQMRTLTSLLYSVDLINYLLLFSIAALSIQLWLAETV 298
Query: 275 TVGELVAFLTYMLTM-------MWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPP 327
TVG + +T L M MW +RAL ++G + S+ + ++ D P
Sbjct: 299 TVGVIAIGITIALRMQGMSKWIMWEIRALFESVGTVIDSMNTIANPVEIEDR-------P 351
Query: 328 DAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIAR 387
A + GE+ F V Y +TV ++ ++ GEKV I G G+GKS+++ L+ R
Sbjct: 352 QAKSLQVKFGELSFSQVRFGYSAQKTVFDDLNLVIQAGEKVGIVGRSGAGKSTLVNLLLR 411
Query: 388 FYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVER 447
FY G++ IDG +++ + E+LR+ + + Q+ + +RSIR+NI P+A Q +E
Sbjct: 412 FYDVQSGQIRIDGQDISHVSQESLRRHIGMITQDTSLLHRSIRDNILYGNPDADQAAIEE 471
Query: 448 AAKIAKIHDFIASLPK-----GYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDP 502
AA+ A HDFI L GYD VGE+G+ LSGGQRQRIA+AR +L N I+++D+
Sbjct: 472 AARQAHAHDFIQELQDEQGRTGYDVQVGERGVKLSGGQRQRIAIARVLLKNAPILIMDEA 531
Query: 503 VSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIK 562
S LD+E E + E+L ++ KT + ++ RLS + +DR+IVM +GKIVE G +EL+
Sbjct: 532 TSALDSEVESAIQENLHTLMAGKTVIAIAHRLSTIAAMDRLIVMDEGKIVEQGTHQELLA 591
Query: 563 KGGIFSEMM--KAGGVYG 578
GI++++ + GG G
Sbjct: 592 HKGIYAQLWAHQTGGFIG 609
>dbj|BAB13177.1| (AP001119) mdlB [Buchnera sp. APS]
Length = 590
Score = 227 bits (572), Expect = 3e-58
Identities = 156/569 (27%), Positives = 278/569 (48%), Gaps = 9/569 (1%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGL--L 65
L RLL Y++ H ++ ++ S + + P+LI I+ +S + I + L
Sbjct: 21 LKRLLIYVKPHKKKLILAFIFLLSGSTSEVLGPILISYFINNILSKHQLHLLIILTIITL 80
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+++ +L+ + L K A ++ LR D A + + FD GQ+IS++TN
Sbjct: 81 FIILQILSVFLNYFQSILFNKIAVESINKLRQDVMYAALQQPISEFDSQPIGQMISKVTN 140
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DTE + L SI LI I L+ M + + +VAL + +V+ + Y
Sbjct: 141 DTEAVKELYDTVGPTLFRSIILIFIILFAMFTLEWHMALVALFILPLVITIMLVYQYYST 200
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
P+ K+R+ I + TI G+ I+ + Q K + ++ Y +K +++
Sbjct: 201 PLLRKVRYYLAEINNKFNETINGMNVIQQFCQQRRFQEKIKKSSDLHYMSRMKILRLDGF 260
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+L + F + VG L AF+TY+ + PL A+ +Q+
Sbjct: 261 LLRPLLSLLSSMILCNFMFLFSFFPVGAFEVGVLYAFITYLGRLNEPLIAITIQQSVLQQ 320
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVLKGVSFKVK 363
S+ A R+F +IDS + + S G+I ++V YH + +L+ ++ K+
Sbjct: 321 SIVAGERIFSLIDSPKQKYGKNKDLLKS---GKINIQNVSF-YHKNCNKNILENINIKIS 376
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
V G GSGKS++ LI +Y G++ +D ++ I LR+ V V Q+P
Sbjct: 377 SKSFVAFVGHTGSGKSTLANLIMGYYPLKNGKIYLDDKSIDSISHSVLRRNVLMVQQDPI 436
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+ + + NI L + +E+V + D + S+PKG +++GE+G LS GQ+Q
Sbjct: 437 VLSDTFFYNITLGR-KIPEEKVWNILDTVHLSDLVKSMPKGIYSLLGEEGNNLSVGQKQL 495
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
+A+AR ++ PK+++LD+ +N+D+ TE+ + + L I ++ T +I++ RLS + D +
Sbjct: 496 LAIARVLVAYPKVLILDEATANIDSGTEQLIQKTLLSIRKNCTLIIIAHRLSTIIEADSI 555
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
IV+K GKIVE G E+L+ K + +M K
Sbjct: 556 IVLKKGKIVEFGTHEQLLTKKSCYYKMYK 584
>sp|P57552|MDLB_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLB
Length = 580
Score = 227 bits (572), Expect = 3e-58
Identities = 156/569 (27%), Positives = 278/569 (48%), Gaps = 9/569 (1%)
Query: 8 LIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGL--L 65
L RLL Y++ H ++ ++ S + + P+LI I+ +S + I + L
Sbjct: 11 LKRLLIYVKPHKKKLILAFIFLLSGSTSEVLGPILISYFINNILSKHQLHLLIILTIITL 70
Query: 66 ILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITN 125
+++ +L+ + L K A ++ LR D A + + FD GQ+IS++TN
Sbjct: 71 FIILQILSVFLNYFQSILFNKIAVESINKLRQDVMYAALQQPISEFDSQPIGQMISKVTN 130
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVR 185
DTE + L SI LI I L+ M + + +VAL + +V+ + Y
Sbjct: 131 DTEAVKELYDTVGPTLFRSIILIFIILFAMFTLEWHMALVALFILPLVITIMLVYQYYST 190
Query: 186 PIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITAL 245
P+ K+R+ I + TI G+ I+ + Q K + ++ Y +K +++
Sbjct: 191 PLLRKVRYYLAEINNKFNETINGMNVIQQFCQQRRFQEKIKKSSDLHYMSRMKILRLDGF 250
Query: 246 YGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQR 305
+L + F + VG L AF+TY+ + PL A+ +Q+
Sbjct: 251 LLRPLLSLLSSMILCNFMFLFSFFPVGAFEVGVLYAFITYLGRLNEPLIAITIQQSVLQQ 310
Query: 306 SLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTG--RTVLKGVSFKVK 363
S+ A R+F +IDS + + S G+I ++V YH + +L+ ++ K+
Sbjct: 311 SIVAGERIFSLIDSPKQKYGKNKDLLKS---GKINIQNVSF-YHKNCNKNILENINIKIS 366
Query: 364 PGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPF 423
V G GSGKS++ LI +Y G++ +D ++ I LR+ V V Q+P
Sbjct: 367 SKSFVAFVGHTGSGKSTLANLIMGYYPLKNGKIYLDDKSIDSISHSVLRRNVLMVQQDPI 426
Query: 424 IFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQR 483
+ + + NI L + +E+V + D + S+PKG +++GE+G LS GQ+Q
Sbjct: 427 VLSDTFFYNITLGR-KIPEEKVWNILDTVHLSDLVKSMPKGIYSLLGEEGNNLSVGQKQL 485
Query: 484 IALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRV 543
+A+AR ++ PK+++LD+ +N+D+ TE+ + + L I ++ T +I++ RLS + D +
Sbjct: 486 LAIARVLVAYPKVLILDEATANIDSGTEQLIQKTLLSIRKNCTLIIIAHRLSTIIEADSI 545
Query: 544 IVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
IV+K GKIVE G E+L+ K + +M K
Sbjct: 546 IVLKKGKIVEFGTHEQLLTKKSCYYKMYK 574
>pir||F82391 ABC transporter, ATP-binding protein VCA0996 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9658438|gb|AAF96892.1| (AE004426) ABC transporter,
ATP-binding protein [Vibrio cholerae]
Length = 619
Score = 226 bits (569), Expect = 7e-58
Identities = 159/575 (27%), Positives = 291/575 (49%), Gaps = 36/575 (6%)
Query: 24 IGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILL-VGVLNGVFSLAGRY 82
I + + L + +V L ++ D + T I GLL+L+ + +L +SL
Sbjct: 49 IAIIEVSLFGFMGQLVDWLSTSSPDTFL-TENQSTLIGLGLLVLVGMPLLIAFYSLLIHQ 107
Query: 83 LLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT----ERITRFLSFRV 138
L+ ++ +L A R + + + F+ F+G++ +++ E + + L V
Sbjct: 108 SLLGNYPMSIRWL---AHRYLLKQSVSFYQDEFAGRISTKVMQTALAVRETVMKSLDVFV 164
Query: 139 RMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVI 198
+++Y +++I + + + L + LI +AI V + Y K++ + + ++
Sbjct: 165 YVMVYFTAIVVI----LAQADWRLMIPMLIWLAIYVTVQMYYVPKLKKVASEQADARSLM 220
Query: 199 ASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV-KAMKITALYGNAPFLVLGLA 257
+ + I T+K S + +T++++E + + V + M++ + + L
Sbjct: 221 SGRIVDSYTNIMTVKLFSHSQR-ETQYAEEGMQDFLGTVHRQMRLVTGFNIWVEMANYLL 279
Query: 258 MSTMFYYGGKAIIQNTLTVGELVAFLTYMLTM-------MWPLRALGFTIGDIQRSLAAA 310
+ T+ I + ++VG + ++ L + MW + AL IG + +
Sbjct: 280 VFTIAALSIYLWITSAISVGAIAVAVSLSLRINGMSKWIMWEVSALFENIGTVVDGMTML 339
Query: 311 SRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLI 370
+ V D PDA + G I F DV Y + V+ ++ +KPGEKV +
Sbjct: 340 GKPITVTDK-------PDAKPLVVKHGGITFDDVSFHYGENKGVINHLNLNIKPGEKVGL 392
Query: 371 TGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIR 430
G G+GKS+++ L+ RF+ G +LIDG ++++ E+LR + V Q+ + +RSIR
Sbjct: 393 VGRSGAGKSTLVNLLLRFHDVESGRILIDGQPISEVTQESLRSKIGMVTQDTSLLHRSIR 452
Query: 431 ENIALAKPNATQEEVERAAKIAKIHDFIASLP-----KGYDTVVGEKGITLSGGQRQRIA 485
+NI PNAT+E++ +A A H+FI L GYD VGE+G+ LSGGQRQRIA
Sbjct: 453 DNILYGNPNATEEQLLKATAQAHAHEFILGLTDPHGNSGYDAQVGERGVKLSGGQRQRIA 512
Query: 486 LARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIV 545
++R +L + +++LD+ S LD+E E + E L E++Q KT + ++ RLS + +DR+IV
Sbjct: 513 ISRVLLKDAPLLVLDEATSALDSEVEAAIQESLNELMQGKTVIAIAHRLSTIAAMDRLIV 572
Query: 546 MKDGKIVEDGKPEELIKKGGIFSEMM--KAGGVYG 578
+ G+IVE G +ELI + GI++ + + GG G
Sbjct: 573 LDKGQIVEQGTHQELIAQNGIYAHLWAHQTGGFIG 607
>sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1)
>gi|159370|gb|AAA16255.1| (L08091) multidrug resistance
protein [Leishmania enriettii]
Length = 1280
Score = 225 bits (568), Expect = 9e-58
Identities = 162/545 (29%), Positives = 278/545 (50%), Gaps = 22/545 (4%)
Query: 50 GVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLL-VKAAQYAVYYLRMDAFRAIQRHEM 108
GV + K A + L+++ VG+ + + AG + AA V +R+ FRA+ R ++
Sbjct: 103 GVGSAEEKAA-KTSLIMVYVGIAM-LIACAGHVMCWTVAACRQVARIRLLFFRAVLRQDI 160
Query: 109 EFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLY--YMVRMNITLTMVA 166
+ D+ G L +R+T DT I ++ ++ + + + +I ++ +TL M+
Sbjct: 161 GWHDEHSPGALTARMTGDTRVIQNGINDKLSQGIMNGSMGVIGYIAGFVFSWELTLMMIG 220
Query: 167 LITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFS 226
++ IV+ V I + R S+AT + I+T+++ E+ +F+
Sbjct: 221 MMPFIIVMA--AIIGSIVSKITESSRKYFAKAGSLATEVMENIRTVQAFGREDYELERFT 278
Query: 227 QENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYM 286
+ ++ + L ++ ++ + F++G + + ++++ T++
Sbjct: 279 KAVLYAQGRGIRKELASNLSAAVIMALMYVSYTVAFFFGSYLVEWGRRDMADIIS--TFL 336
Query: 287 LTMMWPLRALGFTIGD---IQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRD 343
+M LGF S AAA +F ID P V + + IEFR+
Sbjct: 337 AVLMGSF-GLGFVAPSRTAFTESRAAAYEIFKAIDRVPPVDIDAGGVPVPGFKESIEFRN 395
Query: 344 VWLTYHT--GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGV 401
V Y T G + + +S K+K G+KV +G G GKSS++ LI RFY P G VL+DGV
Sbjct: 396 VRFAYPTRPGMILFRDLSLKIKCGQKVAFSGASGCGKSSVIGLIQRFYDPIGGAVLVDGV 455
Query: 402 NVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASL 461
+ ++ R + V QEP +F ++ EN+ + KPNAT EEV A + A IHD I +L
Sbjct: 456 RMRELCLREWRDQIGIVSQEPNLFAGTMMENVRMGKPNATDEEVVEACRQANIHDTIMAL 515
Query: 462 PKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI 521
P YDT VG G LSGGQ+QRIA+ARA++ P I+LLD+ S LD ++E ++ L ++
Sbjct: 516 PDRYDTPVGPVGSLLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQAALDQL 575
Query: 522 LQ--DKTALIVSQRLSLVKLVDRVIVMK-DG----KIVEDGKPEELIKKGGIFSEMMKAG 574
+Q T ++++ RL+ ++ +DR+ +K DG +I E G +EL++ G F+ + K
Sbjct: 576 IQRGGTTVVVIAHRLATIRDMDRIYYVKHDGAEGSRITESGTFDELLELDGEFAAVAKMQ 635
Query: 575 GVYGG 579
GV G
Sbjct: 636 GVLAG 640
Score = 210 bits (530), Expect = 3e-53
Identities = 151/504 (29%), Positives = 259/504 (50%), Gaps = 22/504 (4%)
Query: 71 VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTE 128
+L+G + AG +L K +R+ FR I R ++ FFD +G L ++ D E
Sbjct: 776 ILHGFYGYAGEHLTTK--------IRVLLFRQIMRQDINFFDIPGRDAGTLAGMLSGDCE 827
Query: 129 RITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIY 188
+ + + + + ++ +I L L +VAL + +++G + T + + Y
Sbjct: 828 AVHQLWGPSIGLKVQTMCIIASGLVVGFIYQWKLALVALACMPLMIGCSLTRRLMING-Y 886
Query: 189 DKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV-KAMKITALYG 247
K R + +I T ++ ++T+ SL+++E+ F E +V K + +YG
Sbjct: 887 TKSR-EGDTDDTIVTEALSNVRTVTSLNMKEDCVEAFQAALREEAPRSVRKGIIAGGIYG 945
Query: 248 NAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSL 307
F+ G+ + F+YG K I + +++ +L G + +
Sbjct: 946 ITQFIFYGV-YALCFWYGSKLIDKGEAEFKDVMIASMSILFGAQNAGEAGAFATKLADAE 1004
Query: 308 AAASRLFDVIDSAPKSIDPPDAVEISNPRG-EIEFRDVWLTYHTG--RTVLKGVSFKVKP 364
A+A R+F VID P +D A G +IE+R+V Y + VL V+ +
Sbjct: 1005 ASAKRVFSVIDRVP-DVDIEQAGNKDLGEGCDIEYRNVQFIYSARPKQVVLASVNMRFGD 1063
Query: 365 GEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI 424
+ G G GKS++++++ARFY+ G + ++G +++ + R+ ++ V QEP +
Sbjct: 1064 ATSNGLIGQTGCGKSTVIQMLARFYERRSGLISVNGRDLSSLDIAEWRRNISIVLQEPNL 1123
Query: 425 FNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRI 484
F+ ++RENI A+ AT EEVE AA++A IH I GYDT VG KG LSGGQ+QRI
Sbjct: 1124 FSGTVRENIRYAREGATDEEVEEAARLAHIHHEIIKWTDGYDTEVGYKGRALSGGQKQRI 1183
Query: 485 ALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK---TALIVSQRLSLVKLVD 541
A+AR +L P+++LLD+ S LD+ TE K+ E + E Q K T + ++ RL+ ++ D
Sbjct: 1184 AIARGLLRRPRLLLLDEATSALDSVTEAKVQEGI-EAFQAKYKVTTVSIAHRLTTIRHCD 1242
Query: 542 RVIVMKDGKIVEDGKPEELIKKGG 565
++I++ G I+E G EEL+ GG
Sbjct: 1243 QIILLDSGCIIEQGSHEELMALGG 1266
>gb|AAA02977.1| (L01572) P-glycoprotein [Leishmania donovani]
Length = 1341
Score = 224 bits (565), Expect = 2e-57
Identities = 156/534 (29%), Positives = 277/534 (51%), Gaps = 17/534 (3%)
Query: 59 AIRYGLLILLVGVLNGVFSLAGRYLL--VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
A + L+++ VG+ G+F G ++L AA +R++ FRA+ R ++ + D+
Sbjct: 172 AAKTSLIMVYVGI--GMFVACGGHVLCWTVAASRQEGRIRLNFFRAVLRQDIGWHDEHSP 229
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLY--YMVRMNITLTMVALITIAIVV 174
G+L +R+T DT I ++ ++ + + + II ++ ++TL MV ++ IV+
Sbjct: 230 GELTARMTGDTRVIQNGINDKLSQGIMNGAMGIIGYIAGFVFSWDVTLVMVGMMPFIIVM 289
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
V + + R S+AT + I+T++ E+ +F++
Sbjct: 290 A--AIIGNIVSKMTESSRKHFAKAGSLATEVMENIRTVQVFGREDYELQRFAEAVLYAQD 347
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
++ L ++ L+ + F++G + + ++++ +L + L
Sbjct: 348 RGIRKEFAGNLSAAVIMALVYLSYTIAFFFGSYLVEWGRRDMADIISTFLAVLMGSFGLG 407
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+ + S AAA +F ID P V ++ + IEFR+V +Y T +
Sbjct: 408 FVAPSATAFTESRAAAYEIFKAIDRVPPVDIDAGGVPVTGFKQSIEFRNVRFSYPTRPDM 467
Query: 355 L--KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR 412
+ + ++ +K G+KV +G G GKSS++ LI RFY P G VL DGV++ ++ + R
Sbjct: 468 ILFRDLNLTIKCGQKVAFSGSSGCGKSSMIGLIQRFYDPVGGAVLCDGVDLRELCLHDWR 527
Query: 413 KIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEK 472
+ V QEP +F ++ EN+ + KPNAT+EEV A + A +HD I SLP Y+T VG
Sbjct: 528 DQIGIVSQEPNLFAGTMMENVRVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAV 587
Query: 473 GITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIV 530
G LSGGQ+QRIA+ARA++ P ++LLD+ S LD ++E ++ L +++Q T +++
Sbjct: 588 GSQLSGGQKQRIAIARALVKRPPVLLLDEATSALDRKSEMEVQRSLDQLMQRGGMTVIVI 647
Query: 531 SQRLSLVKLVDRVIVMK-DG----KIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
+ RL+ ++ VD + +K DG KI E G +EL++ GG F+ M + GV G
Sbjct: 648 AHRLATIRNVDCIYYVKYDGAEGSKITESGTFDELMELGGEFAAMARIQGVSTG 701
Score = 208 bits (523), Expect = 2e-52
Identities = 161/554 (29%), Positives = 283/554 (51%), Gaps = 37/554 (6%)
Query: 30 ILMSYTNSIVPVLIRNAIDKGVS-----TGAYK-VAIRYGLLILLVGVLNGVFSLAGRYL 83
ILM Y ++ VL +++K V T Y + I + + L +L+G + AG +L
Sbjct: 793 ILMGY---MLRVLGEYSVNKNVEQLRSGTNLYAPLFIVFAVANFLGWILHGFYGYAGEHL 849
Query: 84 LVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTERITRFLSFRVRML 141
K +R+ FR I R +M FFD +G L ++ D E + + + +
Sbjct: 850 TTK--------IRVLLFRQIMRQDMNFFDIPGRDAGTLAGMLSGDCEAVHQLWGPSIGLK 901
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
+ ++ ++ + L +VAL + +++G + M + Y K + + +I
Sbjct: 902 VQTVCIVASGIVVSFIYQWKLALVALACMPLLIGCSLAERMMMNG-YTKSK-EGDTSDTI 959
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKIT-ALYGNAPFLVLGLAMST 260
T ++ ++T+ S +++ + F +VK I ++YG F+ A +
Sbjct: 960 VTEALSSVRTVTSFNMKADRVEAFEATLRVEVPRSVKKGIIAGSIYGATQFIYYS-AYAL 1018
Query: 261 MFYYGGKAIIQNTLTVGE-LVAFLTYMLTMMWPLRALGFT--IGDIQRSLAAASRLFDVI 317
F+YG K I + + ++A ++ + A F + D +RS A R+F VI
Sbjct: 1019 CFWYGSKLIDRGEAQFTDVMIASMSILFGAQNAGEAGAFATKLADAERS---AKRVFSVI 1075
Query: 318 DSAPKSIDPPDAVEISNPRG-EIEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPP 374
D P +D + + +G +++FR V Y + VL V+ + G + G
Sbjct: 1076 DRVP-DVDIEQSGDKDLGKGCDVDFRKVQFIYSARPKQVVLASVNLRFGDGMANGLMGQT 1134
Query: 375 GSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIA 434
G GKS+I++++ARFY G + ++G +++ + R+ ++ V QEP +F+ ++RENI
Sbjct: 1135 GCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIAEWRRNISVVLQEPNLFSGTVRENIR 1194
Query: 435 LAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNP 494
A+ +AT EEVE AA++A IH I P GY+T VG KG LSGGQ+QR+A+AR +L P
Sbjct: 1195 YAREDATDEEVEEAARLAHIHWEIMKWPDGYNTEVGYKGSALSGGQKQRVAIARGLLRRP 1254
Query: 495 KIVLLDDPVSNLDAETEKKLVEDLKEILQDK---TALIVSQRLSLVKLVDRVIVMKDGKI 551
K++LLD+ S LD+ TE K+ E + + Q K T++ ++ RL+ ++ D++I++ G I
Sbjct: 1255 KLLLLDEATSALDSVTEAKVQEGI-NVYQAKYGVTSVSIAHRLTTIRHCDQIILLDSGHI 1313
Query: 552 VEDGKPEELIKKGG 565
+E G EEL+ GG
Sbjct: 1314 IEQGSHEELMALGG 1327
>gi|4502457 ATP-binding cassette, sub-family B (MDR/TAP), member 11; ABC member
16, MDR/TAP subfamily; bile salt export pump;
progressive familial intrahepatic cholestasis 2 [Homo
sapiens] >gi|3873243|gb|AAC77455.1| (AF091582) bile salt
export pump [Homo sapiens]
Length = 1321
Score = 224 bits (565), Expect = 2e-57
Identities = 147/489 (30%), Positives = 252/489 (51%), Gaps = 8/489 (1%)
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYS 144
V AA + +R FR I R E+ +FD G+L +R ++D +I ++ ++ + +
Sbjct: 164 VIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQR 223
Query: 145 IFLIIISLYYMVRMNITLTMVALITIAIVVGLNT-TYAMKVRPIYDKIRHQTGVIASIAT 203
+ I LT+V +I+++ ++G+ T + V D +A
Sbjct: 224 MTSTICGFLLGFFRGWKLTLV-IISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVAD 282
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
I+ ++T+ + E+ ++ + ++ + + + ++ L + F+
Sbjct: 283 EVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYAVAFW 342
Query: 264 YGGKAII-QNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK 322
YG ++ + T G LV ++ L + AAA+ +F+ ID P
Sbjct: 343 YGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKP- 401
Query: 323 SID--PPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGK 378
ID D ++ +GEIEF +V Y + V L ++ +KPGE + GP G+GK
Sbjct: 402 IIDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGK 461
Query: 379 SSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKP 438
S+ L+LI RFY P +G V +DG ++ + + LR + V QEP +F+ +I ENI +
Sbjct: 462 STALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGRE 521
Query: 439 NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVL 498
+AT E++ +AAK A ++FI LP+ +DT+VGE G +SGGQ+QR+A+ARA++ NPKI+L
Sbjct: 522 DATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILL 581
Query: 499 LDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPE 558
LD S LD E+E + E L +I T + V+ RLS V+ D +I + G VE G E
Sbjct: 582 LDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHE 641
Query: 559 ELIKKGGIF 567
EL+++ G++
Sbjct: 642 ELLERKGVY 650
Score = 215 bits (542), Expect = 1e-54
Identities = 142/519 (27%), Positives = 255/519 (48%), Gaps = 9/519 (1%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
LL + +G ++ Y K+ + LR FRA+ ++ +FD + G L +
Sbjct: 800 LLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTT 859
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+ D ++ ++ M++ S + +++ + L++V L + T
Sbjct: 860 RLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQT 919
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ + + ++ I ++ I+T+ + E E E+ + ++
Sbjct: 920 RMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKAN 979
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL-RALGFTI 300
I ++ +A S + YGG I L + ++ ++ L RA +T
Sbjct: 980 IYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTP 1039
Query: 301 GDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKG 357
+ ++AA R F ++D P S+ + N +G+I+F D TY + VL G
Sbjct: 1040 SYAKAKISAA-RFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNG 1098
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
+S + PG+ + G G GKS+ ++L+ RFY P +G+V+IDG + K+ + LR +
Sbjct: 1099 LSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGI 1158
Query: 418 VPQEPFIFNRSIRENIALAK--PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
V QEP +F SI +NI E V AAK A++HDF+ SLP+ Y+T VG +G
Sbjct: 1159 VSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQ 1218
Query: 476 LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLS 535
LS G++QRIA+ARA++ +PKI+LLD+ S LD E+EK + L + + +T ++++ RLS
Sbjct: 1219 LSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLS 1278
Query: 536 LVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++ D + VM G ++E G EEL+ + G + +++ G
Sbjct: 1279 TIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLVTTG 1317
>gb|AAD28285.1|AF136523_1 (AF136523) bile salt export pump [Homo sapiens]
Length = 1321
Score = 224 bits (565), Expect = 2e-57
Identities = 147/489 (30%), Positives = 252/489 (51%), Gaps = 8/489 (1%)
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYS 144
V AA + +R FR I R E+ +FD G+L +R ++D +I ++ ++ + +
Sbjct: 164 VIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQR 223
Query: 145 IFLIIISLYYMVRMNITLTMVALITIAIVVGLNT-TYAMKVRPIYDKIRHQTGVIASIAT 203
+ I LT+V +I+++ ++G+ T + V D +A
Sbjct: 224 MTSTICGFLLGFFRGWKLTLV-IISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVAD 282
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
I+ ++T+ + E+ ++ + ++ + + + ++ L + F+
Sbjct: 283 EVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFW 342
Query: 264 YGGKAII-QNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK 322
YG ++ + T G LV ++ L + AAA+ +F+ ID P
Sbjct: 343 YGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKP- 401
Query: 323 SID--PPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGK 378
ID D ++ +GEIEF +V Y + V L ++ +KPGE + GP G+GK
Sbjct: 402 IIDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMAIKPGEMTALVGPSGAGK 461
Query: 379 SSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKP 438
S+ L+LI RFY P +G V +DG ++ + + LR + V QEP +F+ +I ENI +
Sbjct: 462 STALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGRE 521
Query: 439 NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVL 498
+AT E++ +AAK A ++FI LP+ +DT+VGE G +SGGQ+QR+A+ARA++ NPKI+L
Sbjct: 522 DATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILL 581
Query: 499 LDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPE 558
LD S LD E+E + E L +I T + V+ RLS V+ D +I + G VE G E
Sbjct: 582 LDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHE 641
Query: 559 ELIKKGGIF 567
EL+++ G++
Sbjct: 642 ELLERKGVY 650
Score = 215 bits (542), Expect = 1e-54
Identities = 142/519 (27%), Positives = 255/519 (48%), Gaps = 9/519 (1%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
LL + +G ++ Y K+ + LR FRA+ ++ +FD + G L +
Sbjct: 800 LLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTT 859
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+ D ++ ++ M++ S + +++ + L++V L + T
Sbjct: 860 RLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQT 919
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ + + ++ I ++ I+T+ + E E E+ + ++
Sbjct: 920 RMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKAN 979
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL-RALGFTI 300
I ++ +A S + YGG I L + ++ ++ L RA +T
Sbjct: 980 IYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTP 1039
Query: 301 GDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKG 357
+ ++AA R F ++D P S+ + N +G+I+F D TY + VL G
Sbjct: 1040 SYAKAKISAA-RFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNG 1098
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
+S + PG+ + G G GKS+ ++L+ RFY P +G+V+IDG + K+ + LR +
Sbjct: 1099 LSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGI 1158
Query: 418 VPQEPFIFNRSIRENIALAK--PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
V QEP +F SI +NI E V AAK A++HDF+ SLP+ Y+T VG +G
Sbjct: 1159 VSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQ 1218
Query: 476 LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLS 535
LS G++QRIA+ARA++ +PKI+LLD+ S LD E+EK + L + + +T ++++ RLS
Sbjct: 1219 LSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLS 1278
Query: 536 LVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++ D + VM G ++E G EEL+ + G + +++ G
Sbjct: 1279 TIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLVTTG 1317
>gi|11430459 ATP-binding cassette, sub-family B (MDR/TAP), member 11 [Homo
sapiens]
Length = 1321
Score = 224 bits (564), Expect = 3e-57
Identities = 147/489 (30%), Positives = 252/489 (51%), Gaps = 8/489 (1%)
Query: 85 VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYS 144
V AA + +R FR I R E+ +FD G+L +R ++D +I ++ ++ + +
Sbjct: 164 VIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQR 223
Query: 145 IFLIIISLYYMVRMNITLTMVALITIAIVVGLNT-TYAMKVRPIYDKIRHQTGVIASIAT 203
+ I LT+V +I+++ ++G+ T + V D +A
Sbjct: 224 MTSTICGFLLGFFRGWKLTLV-IISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVAD 282
Query: 204 GTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFY 263
I+ ++T+ + E+ ++ + ++ + + + ++ L + F+
Sbjct: 283 EVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFW 342
Query: 264 YGGKAII-QNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK 322
YG ++ + T G LV ++ L + AAA+ +F+ ID P
Sbjct: 343 YGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKP- 401
Query: 323 SID--PPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGK 378
ID D ++ +GEIEF +V Y + V L ++ +KPGE + GP G+GK
Sbjct: 402 IIDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGK 461
Query: 379 SSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKP 438
S+ L+LI RFY P +G V +DG ++ + + LR + V QEP +F+ +I ENI +
Sbjct: 462 STALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGRE 521
Query: 439 NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVL 498
+AT E++ +AAK A ++FI LP+ +DT+VGE G +SGGQ+QR+A+ARA++ NPKI+L
Sbjct: 522 DATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILL 581
Query: 499 LDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPE 558
LD S LD E+E + E L +I T + V+ RLS V+ D +I + G VE G E
Sbjct: 582 LDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHE 641
Query: 559 ELIKKGGIF 567
EL+++ G++
Sbjct: 642 ELLERKGVY 650
Score = 215 bits (542), Expect = 1e-54
Identities = 142/519 (27%), Positives = 255/519 (48%), Gaps = 9/519 (1%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
LL + +G ++ Y K+ + LR FRA+ ++ +FD + G L +
Sbjct: 800 LLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTT 859
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
R+ D ++ ++ M++ S + +++ + L++V L + T
Sbjct: 860 RLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQT 919
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
+ + + ++ I ++ I+T+ + E E E+ + ++
Sbjct: 920 RMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKAN 979
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL-RALGFTI 300
I ++ +A S + YGG I L + ++ ++ L RA +T
Sbjct: 980 IYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTP 1039
Query: 301 GDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKG 357
+ ++AA R F ++D P S+ + N +G+I+F D TY + VL G
Sbjct: 1040 SYAKAKISAA-RFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNG 1098
Query: 358 VSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAY 417
+S + PG+ + G G GKS+ ++L+ RFY P +G+V+IDG + K+ + LR +
Sbjct: 1099 LSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGI 1158
Query: 418 VPQEPFIFNRSIRENIALAK--PNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGIT 475
V QEP +F SI +NI E V AAK A++HDF+ SLP+ Y+T VG +G
Sbjct: 1159 VSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQ 1218
Query: 476 LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLS 535
LS G++QRIA+ARA++ +PKI+LLD+ S LD E+EK + L + + +T ++++ RLS
Sbjct: 1219 LSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLS 1278
Query: 536 LVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++ D + VM G ++E G EEL+ + G + +++ G
Sbjct: 1279 TIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLVTTG 1317
>dbj|BAA76299.1| (AB003329) LAMDR1 [Leishmania amazonensis]
Length = 1341
Score = 222 bits (560), Expect = 8e-57
Identities = 157/534 (29%), Positives = 273/534 (50%), Gaps = 17/534 (3%)
Query: 59 AIRYGLLILLVGVLNGVFSLAGRYLL--VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
A + L+++ VG+ G+F G ++L AA +R++ FRA+ R ++ + D+
Sbjct: 172 AAKTSLIMVYVGI--GMFVACGGHVLCWTVAASRQEGRIRLNFFRAVLRQDIGWHDEHSP 229
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLY--YMVRMNITLTMVALITIAIVV 174
G+L +R+T DT I ++ ++ + + + II ++ +TL MV ++ IV+
Sbjct: 230 GELTARMTGDTRVIHNGINDKLSQGIMNGAMGIIGYIAGFVFSWELTLVMVGMMPFIIVM 289
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
V + + R S+AT + I+T++ E+ +F++
Sbjct: 290 A--AIIGNIVSKMTESSRKHFAKAGSMATEVMENIRTVQVFGREDYELQRFAEAVLYAQE 347
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
+ +L ++ L+ + F++G + + ++++ +L + L
Sbjct: 348 RGIHKEFAGSLSAAVVMALVYLSYTVAFFFGSYLVEWGRRDMADIISTFLAVLMGSFGLG 407
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+ + S AAA +F I+ P V ++ R IEF +V +Y T +
Sbjct: 408 FVAPSATAFTESRAAAYEIFKTIERVPPVDIDAGGVPVTGFRQSIEFHNVRFSYPTRPDM 467
Query: 355 L--KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR 412
+ + ++ +K G+KV +G G GKSS++ LI RFY P G VL DGV++ ++ + R
Sbjct: 468 ILFRDLNLTIKRGQKVAFSGSSGCGKSSMIGLIQRFYDPVGGAVLCDGVDMRELCLYDWR 527
Query: 413 KIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEK 472
+ V QEP +F ++ EN+ + KPNAT+EEV A + A +HD I SLP Y+T VG
Sbjct: 528 DQIGIVSQEPNLFAGTMMENVRVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAV 587
Query: 473 GITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIV 530
G LSGGQ+QRIA+ARA++ P I+LLD+ S LD ++E ++ L +++Q T +++
Sbjct: 588 GSQLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLMQKGGMTVIVI 647
Query: 531 SQRLSLVKLVDRVIVMK-DG----KIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
+ RL ++ VD + MK DG KI E G +EL+ GG F+ M + GV G
Sbjct: 648 AHRLETIRNVDCIYYMKYDGEEGSKITESGTFDELMALGGEFAAMARIQGVSAG 701
Score = 203 bits (510), Expect = 6e-51
Identities = 153/521 (29%), Positives = 259/521 (49%), Gaps = 31/521 (5%)
Query: 71 VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTE 128
VL+G + AG +L K +R+ FR I R +M FFD +G L ++ D E
Sbjct: 837 VLHGFYGYAGEHLTTK--------IRLLLFRQIMRQDMNFFDIPGRDAGSLAGMLSGDCE 888
Query: 129 RITRF----LSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
+ + + +V+M+ +++S Y + L +VAL + +++G + M +
Sbjct: 889 AVHQLWGPSIGLKVQMVCIIAAGVVVSFIYQWK----LALVALACMPLLIGCSLAERMMM 944
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
Y K + +I T ++ ++T+ S +++ + F VK I
Sbjct: 945 NR-YTKSK-DGDTSDTIVTEALSSVRTVTSFNMKADRVEAFEATLRVETPHGVKKGIIAG 1002
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
A + A + F+YG K I + +++ +L G +
Sbjct: 1003 SINGARQFIHYGAFALCFWYGSKLIDRGEAQFTDVMIASMSILFGAQSTGDAGAFATKLA 1062
Query: 305 RSLAAASRLFDVIDSAPKSIDPPDAVEISNPRG-EIEFRDVWLTYHTG--RTVLKGVSFK 361
+ +A R+F VID P +D + + +G +++FR V Y + VL V+ +
Sbjct: 1063 EAERSAKRVFSVIDRVP-DLDIEQSGDKDLGKGCDVDFRKVQFIYSARPKQAVLASVNLR 1121
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
G + G G GKS+I++++ARFY G + ++G +++ + R+ ++ V QE
Sbjct: 1122 FGDGTTNGLIGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIAEWRRNISVVLQE 1181
Query: 422 PFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQR 481
P +F+ ++RENI A+ +AT EEVE AA++A IH I P GY+T VG KG LSGGQ+
Sbjct: 1182 PDLFSGTVRENIRYAREDATDEEVEEAARLAHIHQEIMKWPGGYNTEVGYKGSALSGGQK 1241
Query: 482 QRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK---TALIVSQRLSLVK 538
QR+A+AR +L PK++LLD+ S LD TE K V+D Q K T++ ++ RL+ ++
Sbjct: 1242 QRVAIARGLLRRPKLLLLDEATSALDNVTEAK-VQDGINAYQAKYGVTSVSIAHRLTTIR 1300
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
D++I++ G I+E G EEL+ GG E M +Y G
Sbjct: 1301 HCDQIILLDAGHIIEQGSHEELMALGG---EYMMRYNLYTG 1338
>pir||T29110 multidrug resistance protein 1 - Aureobasidium pullulans
>gi|7522025|pir||T30191 multidrug resistance protein 1 -
Aureobasidium pullulans >gi|4097503|gb|AAD00105.1|
(U62928) MULTIDRUG RESISTANCE PROTEIN, ABC TRANSPORTER
PROTEIN [Aureobasidium pullulans]
>gi|4099312|gb|AAD00580.1| (U85909) multidrug
resistance-like protein [Aureobasidium pullulans]
Length = 1302
Score = 222 bits (559), Expect = 1e-56
Identities = 158/540 (29%), Positives = 271/540 (49%), Gaps = 39/540 (7%)
Query: 65 LILLVGVLNGVFSLAGRYLLVK-AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
L+ + L +FS AG + + V ++ + +I R +M++F L+S +
Sbjct: 767 LLFFILALIALFSYAGNGCCFGIVSSHFVAKIQHISLASILRQDMQWFSGQSVPSLMSSL 826
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIIS------LYYMVRMNITLTMVALITIAIVVGLN 177
++D ++ + +IF + +S L ++V I + ++A + + I G
Sbjct: 827 SSDAGQLACLSGVAIG----TIFTVCVSITGGIILAHVVAWKIAVVLLAAVPVMITAGY- 881
Query: 178 TTYAMKVRPIYDKIRHQTGV--IASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSL 235
++V + + RH++ ASIA GI+TI SL E V + +E Y
Sbjct: 882 --VRLRVLALAES-RHRSAYNDAASIAAEACRGIRTIASLGRERGVSRASNAAVKEPYDK 938
Query: 236 NVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRA 295
++ IT F + + +++G K + T + + L +L
Sbjct: 939 GIRFTLITNTLLALSFSITYFVYALAYWWGAKQVRNGTYSQLDFFIVLPALLFSAQSAGQ 998
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP---------------PDAVEISNPR--GE 338
+ ++ R+ AA +F + D P +D P + ++P G
Sbjct: 999 IFSLSPEMSRAGVAARNVFGLHDQKPTIVDVDAKQSGALPSSTLSIPTLEDKASPSSGGW 1058
Query: 339 IEFRDVWLTYHTG--RTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEV 396
IEF++V L Y + L+ V+ ++PGE + + GP G+GKS+IL L+ RFY PT G V
Sbjct: 1059 IEFKNVSLCYPSKPQHPALQNVNISIRPGEFIALVGPSGAGKSTILSLLQRFYDPTAGSV 1118
Query: 397 LIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIAL-AKPN--ATQEEVERAAKIAK 453
+DG ++ ++ R + VPQEP +F SI NI L A P T++++E+
Sbjct: 1119 QLDGQDIREVAVPQHRGRLGLVPQEPDLFPGSISYNIGLGAAPGQLVTRDDIEKICAKCG 1178
Query: 454 IHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKK 513
IH+FI SLP+GY T G G LSGGQ+QRIA+ARA++ +P+++LLD+ S LDA +E++
Sbjct: 1179 IHEFIMSLPEGYSTECGTNGSKLSGGQKQRIAVARALIRSPEVLLLDEYTSALDAHSEQQ 1238
Query: 514 LVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+ E + D+T ++V+ RLS V+ DR+ V DG++VE G EL+ +GG+++ M+ A
Sbjct: 1239 IKEAVDGASVDRTTIVVAHRLSTVQNADRIFVFDDGRVVEVGSHAELVAQGGLYAGMVLA 1298
Score = 156 bits (390), Expect = 7e-37
Identities = 135/533 (25%), Positives = 244/533 (45%), Gaps = 32/533 (6%)
Query: 65 LILLVGVLNGVFSLAGRYLLV--KAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISR 122
L LVGV G F + Y + + R + E +FD + +
Sbjct: 123 LYQLVGVACGYFIVTTGYAIAWGLTGEKISRRFRETLVERLLGLEQAYFDIK-DPDITNL 181
Query: 123 ITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM 182
+T E I S +V + + SI + + +N LT + + ++ L T
Sbjct: 182 LTEKIEAIQIGTSEKVGIFIQSISYFVAAFIVGFILNAKLTGILFAAVIPLMALIVTVGS 241
Query: 183 KVRPIYDKIRHQ-TGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNV---- 237
Y K + T IA I +K +++ + EN+ S+E+ L L+
Sbjct: 242 SRIAKYTKAATEYTEAAGRIAESAIHAVKVVQAFGMAENL----SKEHYRLLKLSARYAI 297
Query: 238 -KAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQN-TLTVGELVAFLTYMLTMMWPLRA 295
K++ + G F A + F+ G + ++ + G + A + ++ + +
Sbjct: 298 RKSVSAAFMLGLVYFTAYS-ANALAFWEGSRLAAESGSNNAGTVYAVVFLIIDASFVVGQ 356
Query: 296 LGFTIGDIQRSLAAASRLFDVIDSAPKSIDP-----PDAVEISNPRGEIEFRDVWLTY-- 348
G +G + AA ++++++ I+ +A E S+ + ++ FR+V Y
Sbjct: 357 FGPFLGSFATAAAAGESVYEILNHPQSEINVYSEAGQEATE-SDMKADLVFRNVTFVYPA 415
Query: 349 HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
T L+ +S +K G+ I G G GKS+++ L+ R Y + G++ I ++
Sbjct: 416 RTSARALEEMSLILKAGQMNAIVGTSGCGKSTLVSLLLRLYDISSGQLTIGSHDIKDFNV 475
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALA------KPNATQEEVERAAKIAKIHDFIASLP 462
+LRK A V Q+ +F+ S+ ENI+ + E AAK A + DF+ LP
Sbjct: 476 RSLRKYTALVDQDSVLFSGSVLENISYGLGEHSLSDDVVLERCTEAAKAANL-DFVDFLP 534
Query: 463 KGYDTVVGEKGIT-LSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI 521
+G T +G G T LSGGQ QRI LARA++ P ++LLD+P + LDA +E +++ +K +
Sbjct: 535 QGIHTRIGNGGYTSLSGGQNQRICLARALVKKPALLLLDEPTAALDANSEGLIMDAVKSV 594
Query: 522 LQDKTALI-VSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
T ++ V+ RLS V +++M GK++E G +EL++ G + +++A
Sbjct: 595 AATGTTVVMVAHRLSTVSDSPNIVLMGAGKVIEQGNHDELMQLEGAYFNLIQA 647
>sp|P18768|CHVA_AGRTU BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTEIN CHVA (ATTACHMENT
PROTEIN) >gi|72494|pir||VXAGCA beta-1,2-glucan export
protein chvA - Agrobacterium tumefaciens
>gi|142224|gb|AAA22083.1| (M24198) attachment protein
ChvA (ttg strart codon) [Agrobacterium tumefaciens]
Length = 588
Score = 221 bits (558), Expect = 1e-56
Identities = 160/572 (27%), Positives = 276/572 (47%), Gaps = 13/572 (2%)
Query: 10 RLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLV 69
R L YL H + + ++++ PVL ID +S+G I LIL
Sbjct: 9 RALRYLTVHKWRVAVVVIANVILAAITIAEPVLFGRIID-AISSGTNVTPI----LILWA 63
Query: 70 GVLNGVFSLAGRYLLVKAAQYAVYYLRM----DAFRAIQRHEMEFFDKTFSGQLISRITN 125
G GVF+ + + A + R +AF I + + + + +
Sbjct: 64 GF--GVFNTVAYVAVAREADRLAHGRRATLLTEAFGRIISMPLSWHHLRGTSNALHTLLR 121
Query: 126 DTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAM-KV 184
+E + +R L + +++ + + M++ L+ V LI + IV + M +
Sbjct: 122 ASETLFGLWLEFMRTHLATFVALVLLIPTAMAMDLRLSFV-LIGLGIVYWFIGKWVMGRT 180
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
+ + + + + +I+ + + S + E E+L S + A
Sbjct: 181 KDGQASVEEHYHSVFAHVSDSISNVSVLHSYNRIEAETKALKSFTEKLLSAQYPVLDWWA 240
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
++M + G + L VG+++AF+ + ++ L + + I
Sbjct: 241 FASALNRTASTVSMMIILVIGTVLVKNGELRVGDVIAFIGFANLLIGRLDQMRQFVTQIF 300
Query: 305 RSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKP 364
+ A F + D+ + +P DA E+SN G +EFR++ + + + VSF K
Sbjct: 301 EARAKLEDFFVLEDAVKEREEPGDARELSNVSGTVEFRNINFGFANTKQGVHDVSFTAKA 360
Query: 365 GEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFI 424
GE V I GP G+GK++++ L+ R Y P G++LIDG +++ + +LR +A V Q+ +
Sbjct: 361 GETVAIVGPTGAGKTTLINLLQRVYDPDSGQILIDGTDISTVTKNSLRNSIATVFQDAGL 420
Query: 425 FNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRI 484
NRSIRENI L + AT EV AA A DFI S GY T VGE+G LSGG+RQRI
Sbjct: 421 LNRSIRENIRLGRETATDAEVVEAAAAAAATDFIDSRINGYLTQVGERGNRLSGGERQRI 480
Query: 485 ALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVI 544
A+ARA+L N I++LD+ S LD ETE ++ + + +++T I++ RLS V+ D V+
Sbjct: 481 AIARAILKNAPILVLDEATSALDVETEARVKAAVDALRKNRTTFIIAHRLSTVRDADLVL 540
Query: 545 VMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
+ G+I+E G +EL ++GG F+ +++ G+
Sbjct: 541 FLDQGRIIEKGTFDELTQRGGRFTSLLRTSGL 572
>gb|AAF71764.1|AF263912_3 (AF263912) NysH [Streptomyces noursei]
Length = 584
Score = 221 bits (558), Expect = 1e-56
Identities = 145/568 (25%), Positives = 280/568 (48%), Gaps = 8/568 (1%)
Query: 8 LIRLL-SYLRGHA--VHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGL 64
L+RLL + LR +A L+ L L+ ++ ++P L ID+GV G G+
Sbjct: 2 LLRLLRAQLRPYAWATAALVALQLVQILG--TLLLPTLGAALIDQGVVRGDGGRITELGV 59
Query: 65 LILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRIT 124
++ +V ++ +L L + A LR FR I + + L++R
Sbjct: 60 VMGVVALVQIAAALGAAALAARTATAMGRDLRSALFRRILDFSAREIGRFGTPSLLTRSV 119
Query: 125 NDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
ND +++ +++ + + + S+ +R ++ L ++ + + +V ++
Sbjct: 120 NDVQQVQNLAQTGFGIVVCAPLMCLGSVLLALRQDVPLALLLVALVLVVAVCFGLLLARM 179
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
+Y +++ + + I G++ ++S +++ + +F+Q N+ ++ + ++ A
Sbjct: 180 GTLYARMQLTLDRLGRLLREAITGVRVVRSFVRDDHERARFAQTNDAFLVVSRRVGRLIA 239
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
L++ + + G I + +G L A L+Y+ ++ + L F +
Sbjct: 240 TMLPVVLLLMNGFTVALLWTGSHRIDAGRMPIGSLSALLSYLSLILMSVVMLAFVFLSVP 299
Query: 305 RSLAAASRLFDVIDSAPKSIDPPDAVE-ISNPRGEIEFRDVWLTYHTGRT-VLKGVSFKV 362
R+ A R+ +V+D+ S+ PP A + + P G IE Y VL+ V V
Sbjct: 300 RARVCAGRIAEVLDTG-SSVAPPAAPQPVRGPAGRIELCAAGYRYPGAEEPVLRDVDLTV 358
Query: 363 KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEP 422
+PGE++ + G GSGK+++L L+ R T+G V + G +V ++ L V +VPQ P
Sbjct: 359 EPGERIAVLGSTGSGKTTLLNLVLRLADATEGAVRVGGTDVRELTAATLAAAVGFVPQRP 418
Query: 423 FIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQ 482
++F+ ++ N+ +P+AT EE+ A ++A+ DF+A +P G D + + G +SGGQRQ
Sbjct: 419 YLFSGTVASNLRFGRPDATDEELWEALRVAQAADFVARMPDGLDAEITQGGGNVSGGQRQ 478
Query: 483 RIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDR 542
R++LARA+L P+I L DD S LD T+ L L T + V+QR+S + DR
Sbjct: 479 RLSLARALLRRPEIYLFDDCFSALDQATDAALRTALVPYTAGATVITVAQRISAGRDADR 538
Query: 543 VIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++V+ G++V G + L++ + E+
Sbjct: 539 IVVLDRGRVVAQGTHDVLLRTSPTYREI 566
>pir||JG0166 LaMDR1 protein - Leishmania mexicana amazonensis
Length = 1341
Score = 220 bits (556), Expect = 2e-56
Identities = 156/534 (29%), Positives = 272/534 (50%), Gaps = 17/534 (3%)
Query: 59 AIRYGLLILLVGVLNGVFSLAGRYLL--VKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFS 116
A + L+++ VG+ G+F G ++L + AA +R++ FRA+ R ++ + D+
Sbjct: 172 AAKTSLIMVYVGI--GMFVACGGHVLCWIVAASRQEGRIRLNFFRAVLRQDIGWHDEHSP 229
Query: 117 GQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLY--YMVRMNITLTMVALITIAIVV 174
G+L +R+T DT I ++ ++ + + + II ++ +TL MV ++ IV+
Sbjct: 230 GELTARMTGDTRVIHNGINDKLSQGIMNGAMGIIGYIAGFVFSWELTLVMVGMMPFIIVM 289
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
V + + R S+AT + I+T++ E+ +F++
Sbjct: 290 A--AIIGNIVSKMTESSRKHFAKAGSMATEVMENIRTVQVFGREDYELQRFAEAVLYAQE 347
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLR 294
+ +L ++ L+ + F++G + + ++++ +L + L
Sbjct: 348 RGIHKEFAGSLSAAVVMALVYLSYTVAFFFGSYLVEWGRRDMADIISIFLAVLMGSFGLG 407
Query: 295 ALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTV 354
+ + S AAA +F I+ P V ++ R IEF +V +Y T +
Sbjct: 408 FVAPSATAFTESRAAAYEIFKTIERVPPVDIDAGGVPVTGFRQSIEFHNVRFSYPTRPDM 467
Query: 355 L--KGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLR 412
+ + ++ +K G+KV +G G GKSS++ LI RFY P G VL DGV++ ++ + R
Sbjct: 468 ILFRDLNLTIKRGQKVAFSGSSGCGKSSMIGLIQRFYDPVGGAVLCDGVDMRELCLYDWR 527
Query: 413 KIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEK 472
+ V QEP +F + EN+ + KPNAT+EEV A + A +HD I SLP Y+T VG
Sbjct: 528 DQIGIVSQEPNLFAGIMMENVRVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAV 587
Query: 473 GITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQ--DKTALIV 530
G LSGGQ+QRIA+ARA++ P I+LLD+ S LD ++E ++ L +++Q +++
Sbjct: 588 GSQLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLMQKGGMIVIVI 647
Query: 531 SQRLSLVKLVDRVIVMK-DG----KIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
+ RL ++ VD + MK DG KI E G +EL+ GG F+ M + GV G
Sbjct: 648 AHRLETIRNVDCIYYMKYDGEEGSKITESGTFDELMALGGEFAAMARIQGVSAG 701
Score = 194 bits (488), Expect = 2e-48
Identities = 151/521 (28%), Positives = 257/521 (48%), Gaps = 32/521 (6%)
Query: 71 VLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLISRITNDTE 128
VL+G + AG +L K +R+ FR I R +M FFD +G L ++ D E
Sbjct: 837 VLHGFYGYAGEHLTTK--------IRLLLFRQIMRQDMNFFDIPGRDAGSLAGMLSGDCE 888
Query: 129 RITRF----LSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKV 184
+ + + +V+M+ +++S Y + L +VAL + +++G + M +
Sbjct: 889 AVHQLWGPSIGLKVQMVCIIAAGVVVSFIYQWK----LALVALACMPLLIGCSLAERMMM 944
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
Y K + +I T ++ ++ + S +++ + F VK I
Sbjct: 945 NR-YTKSK-DGDTSDTIVTEALSSVRIVTSFNMKADRVEAFEATLRVETPHGVKKGIIAG 1002
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
A + A + F+YG K I + +++ +L G +
Sbjct: 1003 SINGARQFIHYGAFALCFWYGSKLIDRGEAQFTDVMIASMSILFGAQSTGDAGAFATKLA 1062
Query: 305 RSLAAASRLFDVIDSAPKSIDPPDAVEISNPRG-EIEFRDVWLTYHTG--RTVLKGVSFK 361
+ +A R+F VID P +D + + +G +++FR V Y + VL V+ +
Sbjct: 1063 EAERSAKRVFSVIDRVP-DLDIEQSGDKDLGKGCDVDFRKVQFIYSARPKQAVLASVNLR 1121
Query: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
G + G G GKS+I++++ARFY G + ++G +++ + R+ ++ V QE
Sbjct: 1122 FGDGTTNGLIGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIAEWRRNISVVLQE 1181
Query: 422 PFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQR 481
P +F+ ++RENI A+ +AT EEVE AA++A IH I P GY+T VG KG L GGQ+
Sbjct: 1182 PDLFSGTVRENIRYAREDATDEEVEEAARLAHIHQEIMKWPGGYNTEVGYKGSAL-GGQK 1240
Query: 482 QRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK---TALIVSQRLSLVK 538
QR+A+AR +L PK++LLD+ S LD TE K V+D Q K T++ ++ RL+ ++
Sbjct: 1241 QRVAIARGLLRRPKLLLLDEATSALDNVTEAK-VQDGINAYQAKYGVTSVSIAHRLTTIR 1299
Query: 539 LVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
D++I++ G I+E G EEL+ GG E M +Y G
Sbjct: 1300 HCDQIILLDAGHIIEQGSHEELMALGG---EYMMRYNLYTG 1337
>pir||T42842 bile salt transport protein, ATP-dependent - rat
>gi|3075422|gb|AAC40084.1| (U69487) bile salt export
pump [Rattus norvegicus]
Length = 1321
Score = 219 bits (552), Expect = 7e-56
Identities = 143/479 (29%), Positives = 244/479 (50%), Gaps = 8/479 (1%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
+R FR I R E+ +FD T G+L SR +D E+I ++ ++ L + + L
Sbjct: 174 MRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQLAHFLQRMSTAMCGLLL 233
Query: 155 MVRMNITLTMVALITIAIVVGLNTTY-AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIK 213
LT+V ++ ++ ++G+ + + + SIA ++ I+T+
Sbjct: 234 GFYRGWKLTLV-ILAVSPLIGIGAAVIGLSIAKFTELELKAYAKAGSIADEVLSSIRTVA 292
Query: 214 SLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAII-QN 272
+ E ++ + + + + + ++ + F+YG ++ +
Sbjct: 293 AFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSTLVLDEE 352
Query: 273 TLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID--PPDAV 330
T G LV ++ + + +AA+ +F ID P ID D
Sbjct: 353 EYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATNIFQTIDRQPV-IDCMSGDGY 411
Query: 331 EISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARF 388
++ +GEIEF +V Y + V L +S +KPGE + G G+GKS+ L+LI RF
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSSGAGKSTALQLIQRF 471
Query: 389 YKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA 448
Y P +G V +DG ++ + LR + V QEP +F+ +I ENI + +AT E++ +A
Sbjct: 472 YDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFGREDATMEDIVQA 531
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
AK A ++FI +LP+ +DT+VGE G +SGGQ+QR+A+ARA++ NPKI+LLD S LD
Sbjct: 532 AKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDN 591
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIF 567
E+E ++ E L +I T + V+ RLS V+ D +I + G VE G EEL+++ G++
Sbjct: 592 ESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGTHEELLERKGVY 650
Score = 205 bits (517), Expect = 9e-52
Identities = 149/527 (28%), Positives = 267/527 (50%), Gaps = 25/527 (4%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
L +++G ++ Y K+ + LR F+A+ ++ +FD + G L +
Sbjct: 800 LFFVILGCVSIFTQFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTT 859
Query: 122 RITNDTERITRFLSFRVRMLLYS----IFLIIISLYYMVRMNITLTMV---ALITIAIVV 174
R+ D ++ +V M++ S I ++I+ ++ ++++ +T+ ++ A+
Sbjct: 860 RLATDASQVQGATGSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQT 919
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
+ T +A + + +K I + ++ I+T+ + VE F E + Y
Sbjct: 920 KMLTGFASQDKQALEKA-------GQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYK 972
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL- 293
V+ I L + LA S + YGG I L + ++ + +
Sbjct: 973 TAVRKANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVALSATAVG 1032
Query: 294 RALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEI-SNPRGEIEFRDVWLTYHTGR 352
R +T + ++AA R F ++D P +A E N +G+I+F D TY +
Sbjct: 1033 RTFSYTPSYAKAKISAA-RFFQLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPSRP 1091
Query: 353 T--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTEN 410
VL G+S V PG+ + G G GKS+ ++L+ RFY P +G V+IDG + K+ +
Sbjct: 1092 DIQVLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQF 1151
Query: 411 LRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA---AKIAKIHDFIASLPKGYDT 467
LR + V QEP +F+ SI +NI N + VERA AK A++HDF+ SLP+ Y+T
Sbjct: 1152 LRSNIGIVSQEPVLFDCSIMDNIKYGD-NTKEISVERAIAAAKQAQLHDFVMSLPEKYET 1210
Query: 468 VVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTA 527
VG +G LS G++QRIA+ARA++ +PKI+LLD+ S LD E+EK + L + + +T
Sbjct: 1211 NVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTC 1270
Query: 528 LIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++++ RLS ++ D + V+ G ++E G E+L+ + G + +++ G
Sbjct: 1271 IVIAHRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKLVITG 1317
>pir||T42228 P-glycoprotein sister - rat >gi|3273484|gb|AAC24753.1| (AF010597)
P-glycoprotein sister [Rattus norvegicus]
Length = 1321
Score = 219 bits (552), Expect = 7e-56
Identities = 143/479 (29%), Positives = 244/479 (50%), Gaps = 8/479 (1%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
+R FR I R E+ +FD T G+L SR +D E+I ++ ++ L + + L
Sbjct: 174 MRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQLAHFLQRMSTAMCGLLL 233
Query: 155 MVRMNITLTMVALITIAIVVGLNTTY-AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIK 213
LT+V ++ ++ ++G+ + + + SIA ++ I+T+
Sbjct: 234 GFYRGWKLTLV-ILAVSPLIGIGAAVIGLSIAKFTELELKAYAKAGSIADEVLSSIRTVA 292
Query: 214 SLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAII-QN 272
+ E ++ + + + + + ++ + F+YG ++ +
Sbjct: 293 AFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSTLVLDEE 352
Query: 273 TLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSID--PPDAV 330
T G LV ++ + + +AA+ +F ID P ID D
Sbjct: 353 EYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATNIFQTIDRQPV-IDCMSGDGY 411
Query: 331 EISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARF 388
++ +GEIEF +V Y + V L +S +KPGE + G G+GKS+ L+LI RF
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSSGAGKSTALQLIQRF 471
Query: 389 YKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA 448
Y P +G V +DG ++ + LR + V QEP +F+ +I ENI + +AT E++ +A
Sbjct: 472 YDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFGREDATMEDIVQA 531
Query: 449 AKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDA 508
AK A ++FI +LP+ +DT+VGE G +SGGQ+QR+A+ARA++ NPKI+LLD S LD
Sbjct: 532 AKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDN 591
Query: 509 ETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIF 567
E+E ++ E L +I T + V+ RLS V+ D +I + G VE G EEL+++ G++
Sbjct: 592 ESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGTHEELLERKGVY 650
Score = 206 bits (519), Expect = 5e-52
Identities = 149/527 (28%), Positives = 268/527 (50%), Gaps = 25/527 (4%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
L +++G ++ Y K+ + LR F+A+ ++ +FD + G L +
Sbjct: 800 LFFVILGCVSIFTQFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTT 859
Query: 122 RITNDTERITRFLSFRVRMLLYS----IFLIIISLYYMVRMNITLTMV---ALITIAIVV 174
R+ D ++ +V M++ S I ++I+ ++ ++++ +T+ ++ A+
Sbjct: 860 RLATDASQVQGATGSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQT 919
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
+ T +A + + +K I + ++ I+T+ + VE F E + Y
Sbjct: 920 KMLTGFASQDKQALEKA-------GQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYK 972
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL- 293
V+ I L + LA S + YGG I L + ++ ++ +
Sbjct: 973 TAVRKANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVVLSATAVG 1032
Query: 294 RALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEI-SNPRGEIEFRDVWLTYHTGR 352
R +T + ++AA R F ++D P +A E N +G+I+F D TY +
Sbjct: 1033 RTFSYTPSYAKAKISAA-RFFQLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPSRP 1091
Query: 353 T--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTEN 410
VL G+S V PG+ + G G GKS+ ++L+ RFY P +G V+IDG + K+ +
Sbjct: 1092 DIQVLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQF 1151
Query: 411 LRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA---AKIAKIHDFIASLPKGYDT 467
LR + V QEP +F+ SI +NI N + VERA AK A++HDF+ SLP+ Y+T
Sbjct: 1152 LRSNIGIVSQEPVLFDCSIMDNIKYGD-NTKEISVERAIAAAKQAQLHDFVMSLPEKYET 1210
Query: 468 VVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTA 527
VG +G LS G++QRIA+ARA++ +PKI+LLD+ S LD E+EK + L + + +T
Sbjct: 1211 NVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTC 1270
Query: 528 LIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++++ RLS ++ D + V+ G ++E G E+L+ + G + +++ G
Sbjct: 1271 IVIAHRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKLVITG 1317
>gi|11038656 ATP-binding cassette, sub-family B, member 11; bile salt export
pump [Mus musculus] >gi|6502606|gb|AAF14372.1|AF133903_1
(AF133903) liver bile salt export pump;
sister-of-p-glycoprotein [Mus musculus domesticus]
Length = 1321
Score = 219 bits (551), Expect = 9e-56
Identities = 141/478 (29%), Positives = 241/478 (49%), Gaps = 6/478 (1%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
+R FR I R E+ +FD T G+L SR ++D +I ++ ++ + L + + L
Sbjct: 174 MRKFYFRRIMRMEIGWFDCTSVGELNSRFSDDINKIDEAIADQMALFLQRLSTALSGLLL 233
Query: 155 MVRMNITLTMVALITIAIVVGLNTTY-AMKVRPIYDKIRHQTGVIASIATGTIAGIKTIK 213
LT+V ++ ++ ++G+ + V + SIA ++ I+T+
Sbjct: 234 GFYRGWKLTLV-ILAVSPLIGIGAAVIGLSVAKFTELELKAYAKAGSIADEVLSSIRTVA 292
Query: 214 SLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAII-QN 272
+ E ++ + + + + + ++ + F+YG + ++ +
Sbjct: 293 AFGGENKEVERYEKNLMFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSRLVLDEG 352
Query: 273 TLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP-KSIDPPDAVE 331
T G L+ ++ + + +AAS +F ID P D +
Sbjct: 353 EYTPGTLIQIFLCVIIAAMNIGNASSCLEIFSTGCSAASSIFQTIDRQPVMDCMSGDGYK 412
Query: 332 ISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFY 389
+ +GEIEF +V Y + V L +S +KPGE G G+GKS+ L+LI RFY
Sbjct: 413 LDRIKGEIEFHNVTFHYPSRPEVKILNNLSMVIKPGETTAFVGSSGAGKSTALQLIQRFY 472
Query: 390 KPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAA 449
P +G V +DG ++ + LR + V QEP +F+ +I ENI L + AT E++ +AA
Sbjct: 473 DPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRLGREEATMEDIVQAA 532
Query: 450 KIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAE 509
K A ++FI +LP+ +DT+VGE G +SGGQ+QR+A+ARA++ PKI+LLD S LD E
Sbjct: 533 KDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRKPKILLLDMATSALDNE 592
Query: 510 TEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIF 567
+E K+ L +I T + V+ RLS V+ D +I + G VE G EEL+++ G++
Sbjct: 593 SEAKVQGALNKIQHGHTIISVAHRLSTVRSADVIIGFEHGTAVERGTHEELLERKGVY 650
Score = 211 bits (532), Expect = 2e-53
Identities = 153/529 (28%), Positives = 265/529 (49%), Gaps = 29/529 (5%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
L +++G ++ Y K+ + LR F+A+ R ++ +FD K G L +
Sbjct: 800 LFFVILGCVSLFTQFLQGYNFAKSGELLTKRLRKFGFKAMLRQDIGWFDDLKNNPGVLTT 859
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITI-------AIVV 174
R+ D ++ +V M++ S I +++ N L++V + A+
Sbjct: 860 RLATDASQVQGATGSQVGMMVNSFTNIFVAVLIAFLFNWKLSLVISVFFPFLALSGAVQT 919
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
+ T +A + + I +K I ++ I+T+ + VE F E E+ Y
Sbjct: 920 KMLTGFASQDKEILEKA-------GQITNEALSNIRTVAGIGVEGRFIKAFEVELEKSYK 972
Query: 235 LNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLT---VGELVAFLTYMLTMMW 291
++ + L + LA S + YGG I+ L V +V+ + T +
Sbjct: 973 TAIRKANVYGLCYAFSQGISFLANSAAYRYGGYLIVYEDLNFSYVFRVVSSIAMSATAVG 1032
Query: 292 PLRALGFTIGDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHT 350
R +T + ++AA R F ++D P + + N +G+I+F D TY +
Sbjct: 1033 --RTFSYTPSYAKAKISAA-RFFQLLDRKPPIDVYSGAGEKWDNFQGKIDFIDCKFTYPS 1089
Query: 351 GRT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKT 408
VL G+S V PG+ + G G GKS+ ++L+ RFY P +G V+IDG + K+
Sbjct: 1090 RPDIQVLNGLSVSVDPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNV 1149
Query: 409 ENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERA---AKIAKIHDFIASLPKGY 465
+ LR + V QEP +F+ SI +NI N + VERA AK A++HDF+ SLP+ Y
Sbjct: 1150 QFLRSNIGIVSQEPVLFDCSIMDNIKYGD-NTKEISVERAIAAAKQAQLHDFVMSLPEKY 1208
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
+T VG +G LS G++QRIA+ARA++ +PKI+LLD+ S LD E+EK + L + + +
Sbjct: 1209 ETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQLALDKAREGR 1268
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
T ++++ RLS ++ D + VM G ++E G ++L+ + G + +++ G
Sbjct: 1269 TCIVIAHRLSTIQNSDIIAVMSQGVVIEKGTHKKLMDQKGAYYKLVITG 1317
>pir||T18940 multidrug resistance protein homolog - Caenorhabditis elegans
>gi|3874031|emb|CAA94203.1| (Z70265) Similarity to
C.elegans p-glycoprotein (SW:MDR1_CAEEL), contains
similarity to Pfam domain: PF00005 (ABC transporter),
Score=418.0, E-value=2.8e-122, N=2; PF00664 (ABC
transporter transmembrane region.), Score=177.0,
E-value=9.8e-50, N=2~cDNA > >gi|3880013|emb|CAA94221.1|
(Z70268) Similarity to C.elegans p-glycoprotein
(SW:MDR1_CAEEL), contains similarity to Pfam domain:
PF00005 (ABC transporter), Score=418.0,
E-value=2.8e-122, N=2; PF00664 (ABC transporter
transmembrane region.), Score=177.0, E-value=9.8e-50,
N=2~cDNA >
Length = 1238
Score = 217 bits (548), Expect = 2e-55
Identities = 153/526 (29%), Positives = 252/526 (47%), Gaps = 18/526 (3%)
Query: 58 VAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSG 117
V I +GL VG F L Y LR + + + ++FD +G
Sbjct: 99 VVIHFGL----VGCAFMFFGFIQFSLFKYIGDNTTYRLRHKFILRLLKKDAKYFDTISTG 154
Query: 118 QLISRITNDTERITRFLSFRVRMLLY--SIFLIIISLYYMVRMNITLTMVALITIAIVVG 175
L + + ++ ER + ++ ++ + F I +L + + + ++ IV+
Sbjct: 155 YLSTVLNDNLERFREAFNEKIAFIICFSTDFAIGTALAFYTSWTLA-SYGSVFAFGIVIS 213
Query: 176 --LNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELY 233
LN+T MK G IA A + KT+ SL+ + K+S E +E
Sbjct: 214 GLLNSTSMMKSNEKQSMHYSNAGAIAFQA---LCSFKTVISLNGQTQELEKYSAELKEGE 270
Query: 234 SLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL 293
+ A T+ Y G I T+ +V YML + L
Sbjct: 271 KFGSRRAFFLATSRGLSHFFCNALNGTILYVGADLIYNKTMNTVAIVTLFHYMLFSAFSL 330
Query: 294 RALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNP----RGEIEFRDVWLTYH 349
I + ++ +A+ +FDV+ S I+ E ++ +G + F +V Y
Sbjct: 331 GEAFLHISYLLNAINSATPIFDVLTSDDDMIENNQDNEQTDSNKTIQGMLSFNNVKFAYP 390
Query: 350 TGRTV--LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIK 407
+ V L+G+SF VK GE + + G GSGKS+I++L+ FY G + I ++ I
Sbjct: 391 SRPDVDILRGISFDVKQGECIALVGASGSGKSTIVQLLLHFYNIQSGTIKIGDSHLHDIN 450
Query: 408 TENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDT 467
+ LR + V QEP +FN +I ENI PNAT E+ A + A +DF+ ++ G T
Sbjct: 451 LKQLRNAIGVVSQEPVLFNTTIEENIRFGNPNATSSEIYEALRKANAYDFVCNIKDGLKT 510
Query: 468 VVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTA 527
+VGE+G LSGGQ+QRIA+AR ++ NP I+LLD+ S LD+ +E+ + LK+ + +T
Sbjct: 511 IVGERGAQLSGGQKQRIAIARVLVKNPAILLLDEATSALDSASERAVQLALKKASEGRTT 570
Query: 528 LIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+I++ RLS ++ D+++VM +GKI E G EELI +S +++A
Sbjct: 571 IIIAHRLSTIRHCDKIMVMSNGKIAEVGSHEELISMDREYSNLVRA 616
Score = 203 bits (512), Expect = 3e-51
Identities = 153/527 (29%), Positives = 265/527 (50%), Gaps = 32/527 (6%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQL 119
+ + L++GV+ + + K ++ LR+ +F+ + F+D K +L
Sbjct: 723 WAAMFLVLGVIRPITLYCQFFFFGKVSEKLSTRLRIKSFQHLLSLPCAFYDDPKHSPTRL 782
Query: 120 ISRITNDTERITRFLSFRVRMLLYSI----FLIIISLYYMVRMNITLTMVALITIA-IVV 174
++R+ D I + R+ LL S+ I+I+ YY + LT+ A++ A +
Sbjct: 783 VNRLNTDPSNIKAAVDARLGSLLMSMVSFSLAILIACYYSWK----LTLQAILYYAKFLY 838
Query: 175 GLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYS 234
TT ++K D + + IA + +KT+K+L++E V + E L
Sbjct: 839 KKTTTISIKE----DSVAFENS--NKIAIEVLDNMKTVKALNMEARV---INLVMEYLAV 889
Query: 235 LNVKAMKITALYGNAPFLVLG---LAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMW 291
L + + + G A G + + F +G I+Q + ++ L +T+ +
Sbjct: 890 LKTSYPRRSVVMGLANGFSAGCSQIVYAISFKFGTYLILQKEVIPMDMYLSL---ITLSY 946
Query: 292 PLRALGFTIG---DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY 348
G I D ++++ +A +F++ D S +GE+ +V Y
Sbjct: 947 TSNMAGSAISYMPDFRKAIHSAGLIFNLFTYPATMPFNSDTGSRSITKGEVNGENVKFHY 1006
Query: 349 HT--GRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
H TVL V+ KV+ G+ + I GP GSGKS+I+ L+ FY+ +G + ID NV I
Sbjct: 1007 HQRPDYTVLDSVNLKVEAGKTLAIVGPSGSGKSTIISLLEMFYRADQGFIKIDNDNVENI 1066
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKP-NATQEEVERAAKIAKIHDFIASLPKGY 465
++LR + V Q P +FN SIR+NI N +Q E+E A +IA +F+ LP+G
Sbjct: 1067 NLDHLRSNLGLVSQGPVLFNCSIRDNILYGLTRNISQTEIENALQIANAFNFVFQLPQGL 1126
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
DT+VG++G LSGGQ+QRIA+ RA+L NPK++LLD+ S LD E+EK + L +
Sbjct: 1127 DTIVGDRGAQLSGGQKQRIAITRAILRNPKLLLLDEATSALDTESEKIVQNALDTASERL 1186
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMK 572
+ ++V+ RLS + D + V+++GK+VE G +L+ G + +++
Sbjct: 1187 STIVVAHRLSTIINADSIAVLRNGKVVEQGTHNQLLAVKGDYWRLVQ 1233
>pir||A41464 hemolysin secretion protein CylB - Enterococcus faecalis
>gi|148309|gb|AAA03343.1| (M38052) cytolysin B transport
protein [Enterococcus faecalis]
>gi|559862|gb|AAA62651.1| (L37110) clyB [Plasmid pAD1]
Length = 714
Score = 217 bits (547), Expect = 3e-55
Identities = 160/570 (28%), Positives = 297/570 (52%), Gaps = 31/570 (5%)
Query: 27 FLIILMSYTNSIVPVLIRNAIDKGVST-GAYKVAIRYGLLILLVGVLNGVFSLAGRYL-- 83
F +I++S+ + ++ +LI A + +++ Y LL++L + ++ + +YL
Sbjct: 157 FSLIILSFVSQLLLLLIPIATKYSIDNIRSFQEIPTYVLLLILTSFFSVLYVV--QYLKS 214
Query: 84 -LVKAAQYAVYYLRMDAF-RAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRML 141
+V QY + M ++ + + +F +G+L+ R N I + LS +V
Sbjct: 215 SVVAEFQYEFDFKLMFSYIDKLFSMPLMYFSNRSTGELVFR-ANLNIYIRQILSQKVITT 273
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
L + I L+ MV +I LT++AL+ I+++ L+ + ++ DK + G + I
Sbjct: 274 LIDSLFLGIYLFLMVNYSILLTIIALVLISLIAFLSIINSHTIKRFVDKEIMEQGNVQRI 333
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTM 261
T I GI+TIKS + +++ + + + A++G P ++ + +
Sbjct: 334 ITEAIEGIETIKSANAKKSFLLNWKNMFTSQLLITKNKNRYIAIFGILPEIIQSVMPALF 393
Query: 262 FYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAP 321
G K II N+L++G L+ F++ + +M P+ +L + D +L +V+
Sbjct: 394 LIIGIKLIINNSLSLGSLIGFVSIVTMVMKPILSLVSSYNDFLLLNVYFQKLSEVLTYEE 453
Query: 322 KSIDPPDAVEISNPRGEI---EF----RDVWLTYHT-GRTVLKGVSFKVKPGEKVLITGP 373
K+ + +N +G + EF +V+ T + +L G+SF ++ G+KV I G
Sbjct: 454 KN-------DFNNKKGNVGKEEFIYRVNNVYYTISVFEKNILNGISFDIRKGDKVAIVGR 506
Query: 374 PGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENI 433
GSGKS++LKL+A +P+ GE+L +G ++ N R+ + YV Q IFN +I +NI
Sbjct: 507 SGSGKSTLLKLLAGLLQPSNGEILYEGYPLS--NNSNNRRNIFYVNQNAHIFNETIEKNI 564
Query: 434 ALA-KPNATQEEVER---AAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARA 489
+L KPN++ E +R + +K+ + + +P+ T+V E G SGGQRQ+IALARA
Sbjct: 565 SLEFKPNSSINEKKRLKGSMSKSKMDEVLLGIPQYEKTIVSENGSNFSGGQRQKIALARA 624
Query: 490 MLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDG 549
N +LLD+P S +D +E ++ +L + + +T + V+ R+S VK D++I+M +G
Sbjct: 625 FYSNVNTLLLDEPTSAMDNISEFEVFSNLLD--EKRTVITVAHRISTVKNFDKIILMDNG 682
Query: 550 KIVEDGKPEELIKKGGIFSEMMKAGGVYGG 579
+IV GK E+LI+ ++ + +GG
Sbjct: 683 EIVCIGKHEDLIENSELYRSLYYKKQQFGG 712
>pir||D72083 transport ATP binding protein - Chlamydophila pneumoniae (strain
CWL029) >gi|4376693|gb|AAD18557.1| (AE001624) Transport
ATP Binding Protein [Chlamydophila pneumoniae CWL029]
Length = 659
Score = 217 bits (547), Expect = 3e-55
Identities = 148/534 (27%), Positives = 265/534 (48%), Gaps = 13/534 (2%)
Query: 43 IRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRA 102
+RN ID G + ++ V + V R+L A LR D F+A
Sbjct: 113 VRNYIDVSRFRGL-------AIFLICVAIFKAVTLFFQRFLGQVVAIRVSRDLRQDYFKA 165
Query: 103 IQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITL 162
+Q+ M FF G L +R+ D+ I ++ + + + I++L + ++
Sbjct: 166 LQQLPMTFFHDHDIGNLSNRVMTDSASIALAVNSLMINYIQAPITFILTLGVCLSISWKF 225
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
+++ + I + A K++ + +I+ +S+ +AG+ T+K E+
Sbjct: 226 SILICVAFPIFILPIVVIARKIKNLAKRIQKSQDSFSSVLYDFLAGVMTVKVFRTEKFAF 285
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGK-AIIQNTLTVGELVA 281
TK+ + N ++ +L K+ A YG P +L S F + I + + EL+
Sbjct: 286 TKYCEHNNKISALEEKS----AAYGLLPRPLLHTIASLFFAFVVVIGIYKFAIPPEELIV 341
Query: 282 FLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEF 341
F + + P++ G I R AAA R ++V++ +E I F
Sbjct: 342 FCGLLYLIYDPIKKFGDENTSIMRGCAAAERFYEVLNHPDLHSQKEREIEFLGLSNTITF 401
Query: 342 RDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGV 401
+V Y + +LK +SF + GE + I GP GSGK++++KL+ R Y+ ++G++LID +
Sbjct: 402 ENVSFGYQEDKHILKNLSFTLHKGEALGIVGPTGSGKTTLVKLLPRLYEVSQGKILIDSL 461
Query: 402 NVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASL 461
+ + +LR +A V Q PF+F ++ N+ K + +E V A K A +FI L
Sbjct: 462 PITEYNKGSLRNHIACVLQNPFLFYDTVWNNLTCGK-DMEEEAVLEALKRAYADEFILKL 520
Query: 462 PKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI 521
PKG +V+ E G LSGGQ+QR+A+ARA+L N I++LD+ S LDA +E + + E+
Sbjct: 521 PKGVHSVLEESGKNLSGGQQQRLAIARALLKNASILILDEATSALDAISENYIKNIIGEL 580
Query: 522 LQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGG 575
T +I++ +L+ ++ VDRV+ +++G+ + +G EEL++ F +M + G
Sbjct: 581 KGQCTQIIIAHKLTTLEHVDRVLYIENGQKIAEGTKEELLQTCPEFLKMWELSG 634
>gb|AAF73656.1| (AE002196) ABC transporter, ATP-binding protein [Chlamydophila
pneumoniae AR39] >gi|8978785|dbj|BAA98621.1| (AP002546)
Transport ATP Binding Protein [Chlamydophila pneumoniae
J138]
Length = 659
Score = 217 bits (547), Expect = 3e-55
Identities = 148/534 (27%), Positives = 265/534 (48%), Gaps = 13/534 (2%)
Query: 43 IRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRA 102
+RN ID G + ++ V + V R+L A LR D F+A
Sbjct: 113 VRNYIDVSRFRGL-------AIFLICVAIFKAVTLFFQRFLGQVVAIRVSRDLRQDYFKA 165
Query: 103 IQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITL 162
+Q+ M FF G L +R+ D+ I ++ + + + I++L + ++
Sbjct: 166 LQQLPMTFFHDHDIGNLSNRVMTDSASIALAVNSLMINYIQAPITFILTLGVCLSISWKF 225
Query: 163 TMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQ 222
+++ + I + A K++ + +I+ +S+ +AG+ T+K E+
Sbjct: 226 SILICVAFPIFILPIVVIARKIKNLAKRIQKSQDSFSSVLYDFLAGVMTVKVFRTEKFAF 285
Query: 223 TKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGK-AIIQNTLTVGELVA 281
TK+ + N ++ +L K+ A YG P +L S F + I + + EL+
Sbjct: 286 TKYCEHNNKISALEEKS----AAYGLLPRPLLHTIASLFFAFVVVIGIYKFAIPPEELIV 341
Query: 282 FLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEF 341
F + + P++ G I R AAA R ++V++ +E I F
Sbjct: 342 FCGLLYLIYDPIKKFGDENTSIMRGCAAAERFYEVLNHPDLHSQKEREIEFLGLSNTITF 401
Query: 342 RDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGV 401
+V Y + +LK +SF + GE + I GP GSGK++++KL+ R Y+ ++G++LID +
Sbjct: 402 ENVSFGYQEDKHILKNLSFTLHKGEALGIVGPTGSGKTTLVKLLPRLYEVSQGKILIDSL 461
Query: 402 NVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASL 461
+ + +LR +A V Q PF+F ++ N+ K + +E V A K A +FI L
Sbjct: 462 PITEYNKGSLRNHIACVLQNPFLFYDTVWNNLTCGK-DMEEEAVLEALKRAYADEFILKL 520
Query: 462 PKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEI 521
PKG +V+ E G LSGGQ+QR+A+ARA+L N I++LD+ S LDA +E + + E+
Sbjct: 521 PKGVHSVLEESGKNLSGGQQQRLAIARALLKNASILILDEATSALDAISENYIKNIIGEL 580
Query: 522 LQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGG 575
T +I++ +L+ ++ VDRV+ +++G+ + +G EEL++ F +M + G
Sbjct: 581 KGQCTQIIIAHKLTTLEHVDRVLYIENGQKIAEGTKEELLQTCPEFLKMWELSG 634
>emb|CAA94220.2| (Z70268) Similarity to C.elegans p-glycoprotein (SW:MDR1_CAEEL),
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=404.3, E-value=3.8e-118, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=187.8, E-value=5.5e-53, N=2 [Caen>
Length = 1225
Score = 213 bits (537), Expect = 4e-54
Identities = 139/511 (27%), Positives = 253/511 (49%), Gaps = 44/511 (8%)
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
L G +F+ ++ Y +R + + + ++FD +G L + + ++
Sbjct: 108 LCGCAYFIFASLQHAIMKYVGDNTTYRVRKQYISRLLKKDAQYFDSVSTGHLSTVLNDNL 167
Query: 128 ERITRFLSFRVRMLLYSI--FLIIISLYYMVRMNITLTMVAL-ITIAIVVGLNTTYAMKV 184
ER + ++ +++ + F + +L + + + + IA +N+ MK
Sbjct: 168 ERFREVFNEKIALIIAFVTDFTLGTALAFYTDWRLASYGIFFSLGIAFSGFINSAGVMKT 227
Query: 185 RPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITA 244
+ G SIA T+ KT+ SL+ ++ ++++E + ++ + +
Sbjct: 228 TGKQNTHYANAG---SIAFQTLGAYKTVCSLNGQKTEIERYTEELKAGEKYGIRRALMYS 284
Query: 245 LYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQ 304
+ + + + Y G I TL +V
Sbjct: 285 ISRGVTYFFCNSLNTVVLYVGATMIYSGTLETAVVV------------------------ 320
Query: 305 RSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT--GRTVLKGVSFKV 362
R +VI+ D VE++ G I F++V +Y T VLKG+SF V
Sbjct: 321 -------RDDNVIEKDETDYDVE--VEVN---GNISFKNVKFSYPTRPDAQVLKGISFDV 368
Query: 363 KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEP 422
+ GE + + G GSGKS++++L+ +Y G + IDG+++ + + LR+++ V QEP
Sbjct: 369 QNGECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGMDLNDMNIKRLRRVIGVVSQEP 428
Query: 423 FIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQ 482
+FN +I ENI PN + E+ A + A +DF+ S PKG T+VGE+G LSGGQ+Q
Sbjct: 429 VLFNTTIEENIRFGNPNVSLPEIYGALRKANAYDFVCSFPKGIKTIVGERGTQLSGGQKQ 488
Query: 483 RIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDR 542
RIA+AR ++ NPKI+LLD+ S LD E+E+ + + L+ Q +T ++V+ RLS ++ +
Sbjct: 489 RIAIARTLVRNPKILLLDEATSALDNESEQVVQKALENASQGRTTIVVAHRLSTIRNASK 548
Query: 543 VIVMKDGKIVEDGKPEELIKKGGIFSEMMKA 573
+IVM+ G+IVE G +ELI K G+++++++A
Sbjct: 549 IIVMQKGEIVEVGNHDELIAKRGVYNDLVQA 579
Score = 202 bits (509), Expect = 8e-51
Identities = 145/531 (27%), Positives = 259/531 (48%), Gaps = 27/531 (5%)
Query: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKT--FSGQL 119
+ L + + V + Y K ++ LR+ +F + F+D + +L
Sbjct: 699 WALSFMFLAVFRPLTLYCQYYYFGKVSEQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRL 758
Query: 120 ISRITNDTERITRFLSFRVRMLLYSIFLIII-----SLY-YMVRMNITLTMVALITIAIV 173
+R+ D+ + + R+ ++ ++ I I SLY + + + + + L
Sbjct: 759 SNRLNTDSSNVKAAVDDRLGCVIMTVVAISIAITTASLYCWKMTLEVLMFFPLLYLAEYC 818
Query: 174 VGLNTTYAMKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELY 233
T A++ I + ++T + A + ++T+++L++E+ + + S+ ++++
Sbjct: 819 YEAATETAIQEDTIAFENSNRTAIEA------LENVRTVRALNLEDKIMSLISEHLQKIH 872
Query: 234 SLNVKAMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL 293
K I S F +G ++ E+ TY++ M +
Sbjct: 873 KSYFKRAIIQGAANGLSLSCFLFVYSVSFKFGTYLALRK-----EVAPMDTYLVLMTLSM 927
Query: 294 RA-----LGFTIGDIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTY 348
A + D ++++ AA +F + + + +GEI +V Y
Sbjct: 928 TANMAGSAAAYLPDYKKAVHAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHY 987
Query: 349 --HTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKI 406
R +L GV+ KV PG+ + + GP G GKS+I+ L+ RFY GEV ID NV I
Sbjct: 988 DQRPDRMILNGVNLKVDPGKTLALVGPSGCGKSTIISLLERFYHAVDGEVKIDSENVEDI 1047
Query: 407 KTENLRKIVAYVPQEPFIFNRSIRENIALAKPNAT-QEEVERAAKIAKIHDFIASLPKGY 465
+LR +A V QEP +FN SIREN+ + Q E+E+A + A +F+ P+G
Sbjct: 1048 NLNHLRSNLALVSQEPTLFNCSIRENLLYGLTRSVPQLELEKALQTANAFNFVFQFPQGL 1107
Query: 466 DTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK 525
DT+VGE+G LSGGQ+QRIA+ARA+L NPK++LLD+ S LD+++EK + L +
Sbjct: 1108 DTLVGERGAQLSGGQKQRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERL 1167
Query: 526 TALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGGV 576
+ ++V+ RLS V D + V+K+GK+ E G EEL++K I+ +++ G+
Sbjct: 1168 STVVVAHRLSTVVNADSIAVLKNGKVAEQGTHEELLRKRSIYWRLVQKQGI 1218
>gb|AAD29692.1|AF135793_1 (AF135793) sister of P-glycoprotein [Fundulus heteroclitus]
Length = 765
Score = 212 bits (534), Expect = 9e-54
Identities = 157/527 (29%), Positives = 265/527 (49%), Gaps = 25/527 (4%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
+ ++VGV++ + Y K+ + LR F+A+ E+ +FD + G L +
Sbjct: 244 VFFVIVGVISFFTQMLQGYAFAKSGELLTRRLRRIGFKAMLGQEIGWFDDHRNSPGALTT 303
Query: 122 RITNDTERITRFLSFRVRMLLYSI----FLIIISLYYMVRMNITLTMVALITIAIVVGLN 177
R+ D ++ ++ M++ S+ +I+S Y+ N+TL ++ + + L+
Sbjct: 304 RLATDASQVQGATGSQIGMIVNSLTNIGVALIMSFYFS--SNVTLLILCFLPF---IALS 358
Query: 178 TTYAMKVRPIYDKIRHQTGVIASIATG-TIAGIKTIKSLSVEENVQTKFSQENEELYSLN 236
+ K+ + K Q A +G + I+TI L E + K+ + Y
Sbjct: 359 GGFQAKMLTGFAKQDKQAMESAGQVSGEALNNIRTIAGLGKEGSFVEKYEAHLDSPYQA- 417
Query: 237 VKAMKITALYGNAPFL---VLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL 293
A+K +YG A +L V+ L F +GG + Q L + ++ ++T L
Sbjct: 418 --ALKKANVYG-ACYLAQCVIFLTNGASFRFGGYLVEQEGLHFSLVFRVISAIVTSGTAL 474
Query: 294 -RALGFTIGDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHTG 351
RA +T + +AA F ++D P S+ + N +G +EF TY T
Sbjct: 475 GRASSYTPDYAKAKTSAARFFFQLLDRVPPISVYSNRGEKWDNFQGNLEFVHCKFTYPTR 534
Query: 352 RT--VLKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTE 409
VL G++ V+PG+ + G G GKS+ +L+ RFY P G+VLIDG ++
Sbjct: 535 PDIQVLNGLNVSVRPGQTLAFVGSSGCGKSTSAQLLERFYDPDHGKVLIDGHESTRVSVP 594
Query: 410 NLRKIVAYVPQEPFIFNRSIRENIALAKP--NATQEEVERAAKIAKIHDFIASLPKGYDT 467
LR + V QEP +F+ SI ENI + EV AAK A++HDF+ SLP+ YD
Sbjct: 595 FLRSKIGIVSQEPVLFDCSIAENIKYGDNLREISMNEVISAAKKAQLHDFVMSLPEKYDA 654
Query: 468 VVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTA 527
VG +G LS GQ+QRIA+ARA++ +PKI+LLD+ S LD E+EK + E L + + +T
Sbjct: 655 NVGSQGSQLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKTVQEALDKRREGRTC 714
Query: 528 LIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
++++ RLS ++ D + VM G ++E G ++L+ G + +++ G
Sbjct: 715 IVIAHRLSTIQNSDIIAVMSRGFVIEKGSHDQLMALKGAYYKLVTTG 761
>gb|AAF65552.1|AF249879_1 (AF249879) liver bile salt export pump [Oryctolagus cuniculus]
Length = 1321
Score = 212 bits (533), Expect = 1e-53
Identities = 150/523 (28%), Positives = 263/523 (49%), Gaps = 17/523 (3%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFD--KTFSGQLIS 121
LL + +G ++ Y K+ + LR FRA+ ++ +FD + G L +
Sbjct: 800 LLFVTLGCVSFFTQFLQGYTFAKSGELLTKRLRKFGFRAMLGQDIGWFDDLRNSPGALTT 859
Query: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLY--YMVRMNITLTMVALITIAIVVGLNTT 179
R+ D ++ ++ M++ S + +++ ++ +TL +V + G T
Sbjct: 860 RLATDASQVQGATGSQIGMMVNSFTNVTVAMIIAFLFSWKLTLGIVCFFPFLALSGALQT 919
Query: 180 YAMKVRPIYDK-IRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVK 238
+ DK + G I S A ++ I+T+ + E F E E+ Y + +K
Sbjct: 920 KMLTGFASRDKQALEKAGQITSEA---LSNIRTVAGIGKERKFIETFEAELEKPYKMAIK 976
Query: 239 AMKITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPL-RALG 297
+ L + +A S + YGG I L + ++ ++ L RA
Sbjct: 977 KANVYGLCFGFSQCITFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRASS 1036
Query: 298 FTIGDIQRSLAAASRLFDVIDSAPK-SIDPPDAVEISNPRGEIEFRDVWLTYHTGRT--V 354
+T + ++AA R F ++D P ++ + N +G+I+F D TY + V
Sbjct: 1037 YTPSYAKAKISAA-RFFQLLDRQPPINVYSSAGEKWDNFQGKIDFVDCKFTYPSRPDIQV 1095
Query: 355 LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKI 414
L G+S + P + + G G GKS+ ++L+ RFY P G+V+IDG + K+ + LR
Sbjct: 1096 LNGLSVSMSPRQTLAFVGSSGCGKSTSIQLLERFYDPDHGKVMIDGHDSRKVNIQFLRSN 1155
Query: 415 VAYVPQEPFIFNRSIRENIALAKPNATQEEVER---AAKIAKIHDFIASLPKGYDTVVGE 471
+ V QEP +F SI++NI N + +ER AAK A++HDF+ SLP+ Y+T VG
Sbjct: 1156 IGIVSQEPVLFACSIKDNIKYGD-NTQEIPMERIIAAAKKAQVHDFVMSLPEKYETNVGS 1214
Query: 472 KGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVS 531
+G LS G++QRIA+ARA++ +PKI+LLD+ S LD E+EK + L + + +T ++++
Sbjct: 1215 QGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIA 1274
Query: 532 QRLSLVKLVDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAG 574
RLS ++ D + VM G ++E G EEL+ + G + +++ G
Sbjct: 1275 HRLSTIQNSDIIAVMSQGMVIEKGTHEELMVQKGAYYKLVTTG 1317
Score = 200 bits (504), Expect = 3e-50
Identities = 139/487 (28%), Positives = 242/487 (49%), Gaps = 8/487 (1%)
Query: 87 AAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIF 146
AA + + +R FR I R + + D G+L + + D +I + ++ + + +
Sbjct: 166 AAAHQIQKMRKSYFRKIMRMGIGWVDCNSVGKLNTPFSVDFNKINDSSADQLAIFIQGMT 225
Query: 147 LIIISLYYMVRMNITLTMVALITIAIVVGLNTTY-AMKVRPIYDKIRHQTGVIASIATGT 205
I LT+V +I+++ ++GL + V D S+A
Sbjct: 226 SPIFGFLVGFSQWWKLTLV-IISVSPLIGLGAAIIGLSVSKFTDYELKAYAKAGSVADEV 284
Query: 206 IAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYYG 265
I+ ++T+ + E+ ++ + ++ + + + ++ + F+YG
Sbjct: 285 ISSMRTVAAFGGEKKEVERYEKNLVFAQRWGIRKGIVMGFFTGYMWCLIFFCYALAFWYG 344
Query: 266 GKAIIQN-TLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPKSI 324
K +++ + G LV ++ L + AAAS +F+ ID P I
Sbjct: 345 SKLVLEEGEYSPGALVQIFLSVIIGALNLGNASPCLEAFAAGRAAASSIFETIDRKP-II 403
Query: 325 D--PPDAVEISNPRGEIEFRDVWLTYHTGRTV--LKGVSFKVKPGEKVLITGPPGSGKSS 380
D D ++ +GEIEF +V Y + V L +S +KPGE + GP G+GKS+
Sbjct: 404 DCMSEDGYKLERIKGEIEFHNVTFHYPSRPEVKILNNLSMVIKPGEMTALVGPSGAGKST 463
Query: 381 ILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNA 440
L+LI RFY PT+G V ++ ++ + LR + V QEP +F +I E I + +A
Sbjct: 464 ALQLIHRFYGPTEGMVTVESHDIRSSHIQWLRNQIGIVEQEPVLFFHTIAEKIRYGREDA 523
Query: 441 TQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLD 500
T E++ +AAK A ++FI LP+ +DT+VGE G +SGGQ+QR+A+ARA++ NPKI+LLD
Sbjct: 524 TMEDLIQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLD 583
Query: 501 DPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKPEEL 560
S LD E+E + E L + T + V+ R + ++ D +I + G VE G EEL
Sbjct: 584 MATSALDNESEAMVQEALSKTQHGHTIVSVAHRPATIRTADVIIGCEHGAAVERGTEEEL 643
Query: 561 IKKGGIF 567
+++ G++
Sbjct: 644 LERKGVY 650
>emb|CAB69672.1| (AL137165) probable ABC transporter protein, ATP-binding component.
[Streptomyces coelicolor A3(2)]
Length = 589
Score = 210 bits (528), Expect = 5e-53
Identities = 148/568 (26%), Positives = 273/568 (48%), Gaps = 9/568 (1%)
Query: 9 IRLLSYLRGHAVHFLIGLFLIILMSYTNS-IVPVLIRNAIDKGVSTGAYKVAIRYGLLIL 67
IR L YL L G + + ++ ++P++ +D V G LI+
Sbjct: 19 IRTLVYLFRADRRRLAGAVAVFTVKHSPIWLLPLVTAAIVDTVVQHGPITDLWTSTGLIM 78
Query: 68 LVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDT 127
+ V+N L LL + + LR +Q+ + + + +G L +++ D
Sbjct: 79 FILVVNYPLHLLYVRLLYGSVRRMGTALRSALCTRMQQLSIGYHSRVSAGVLQAKVVRDV 138
Query: 128 ERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPI 187
E + + + L + ++ L + V L+ + L ++R
Sbjct: 139 ETVEQMVQQTAETGLGAFTVLTGGLVIIGVRTPEFLPVFLVVVPAASLLVARLRARLRTH 198
Query: 188 YDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYG 247
++ RH+ ++S T I ++ +E + + L + ++ + +G
Sbjct: 199 NERFRHEVETLSSRVTEMTRLIPVTRAHGLEGKALRRMDGTLDRLLTSGMRLDLVNGRFG 258
Query: 248 NAPFLVLGLAMSTMFYYGGKAIIQNT----LTVGELVAFLTYMLTMMWPLRALGFTIGDI 303
+ ++VL + + G A+I +T G++V ++ T+ L I
Sbjct: 259 SLSWVVLNVVGVVVL--AGAALISYYDVWGVTAGDVVMLSAFLTTLTNSTTTLAGLAPVI 316
Query: 304 QRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHT-GRTVLKGVSFKV 362
+ L + + +V+ AP+ D E++ RG + F V Y + GR + + V
Sbjct: 317 TKGLESVRSVGEVLQ-APELEDNEGKKELTALRGAVAFEGVGHLYDSDGRPAVSDFTLSV 375
Query: 363 KPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEP 422
+PGE + + G G+GKS++L L+ F +PT G +L+DG ++ + R+ V+ VPQE
Sbjct: 376 EPGETIALVGASGAGKSTVLNLVIGFLRPTSGRLLLDGHDMNTLDLRTYRRFVSVVPQES 435
Query: 423 FIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQ 482
+F+ +IREN+A A +E V A + A +F+ LP+G DT+VGE G LSGGQRQ
Sbjct: 436 ILFDGTIRENVAYGMDEADEETVRGALRDANALEFVDRLPRGLDTLVGEHGARLSGGQRQ 495
Query: 483 RIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDR 542
R+A+ARA++ +P++++LD+ S LD +E + + L +L+ +T +V+ RLS V+ DR
Sbjct: 496 RLAIARALIRDPRVLVLDEATSALDTRSEALVQQALARLLRGRTTFVVAHRLSTVRGADR 555
Query: 543 VIVMKDGKIVEDGKPEELIKKGGIFSEM 570
++VM +G+I E G EEL+ GG ++ +
Sbjct: 556 IVVMGEGRIQEIGTHEELLAGGGAYAAL 583
>pir||T30293 ABC transport protein homolog - Salmonella typhi
>gi|1698599|gb|AAB37256.1| (U62129) ATP binding cassette
(ABC) transporter homolog [Salmonella typhi]
Length = 1218
Score = 209 bits (527), Expect = 6e-53
Identities = 135/446 (30%), Positives = 231/446 (51%), Gaps = 27/446 (6%)
Query: 148 IIISLYYMVRMNITLTM---VALITIAIVVGLNTTYAMKVRPIY-------DKIRHQTGV 197
+ + YY+ + + L M + LI I ++ L T R ++ D++ H T
Sbjct: 146 LAVLTYYVAGIAVMLWMSPSMTLIVICVLAALAITALRARRRVFAQTGLASDRLAHMTEH 205
Query: 198 IASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLA 257
+ + + I +KS E ++ ++ + + A A+ G + +
Sbjct: 206 MREV----LEQISVVKSCVAELRETRWLDGQSRQMVRVRIGAAISQAMPGATMLALPVIG 261
Query: 258 MSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVI 317
+ YGG +++ + +G VAF +++ + P R L + QR+ A+ R+F +I
Sbjct: 262 QIVLLCYGGWSVMNGRIDLGTFVAFASFLAMLTGPTRVLASFLVIAQRTQASVERVFALI 321
Query: 318 DSAPKSIDPPDAVEISNPRGEIEFRDVW---LTYHTGRTVLKGVSFKVKPGEKVLITGPP 374
D+ + D ++VE G+I DV Y G +L +SF + GE V + G
Sbjct: 322 DTRSRMEDGTESVE-----GQIIGLDVEKMSFHYDNGNRILNEISFSIHAGETVAVVGAS 376
Query: 375 GSGKSSILKLIARFYKPTKGEVLIDGV----NVAKIKTENLRKIVAYVPQEPFIFNRSIR 430
GSGKS++L L+ARFY PT G V ++ N+ +K LR+ V V ++ F+F ++
Sbjct: 377 GSGKSTLLMLLARFYDPTSGGVWLNTTTGQQNIRDLKLTALRRRVGVVFEDAFLFAGTVA 436
Query: 431 ENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAM 490
ENIA P ATQ+++ RAA A FI +LP+G++T + E+G LSGGQRQRIALARA+
Sbjct: 437 ENIAYGHPQATQDDIRRAADAAGASGFINALPQGFNTRLTERGSNLSGGQRQRIALARAL 496
Query: 491 LMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDK-TALIVSQRLSLVKLVDRVIVMKDG 549
+ P++++LDD S +DA TE ++ L ++ L++++R S ++L DR++V+ G
Sbjct: 497 ITAPELLILDDTTSAVDAGTEAEINTALGRYADNEHMLLVIARRRSTLQLADRIVVLDKG 556
Query: 550 KIVEDGKPEELIKKGGIFSEMMKAGG 575
++V+ G EL + F +M G
Sbjct: 557 RVVDIGTQAELDARCPTFRSLMSGEG 582
Score = 199 bits (501), Expect = 7e-50
Identities = 143/557 (25%), Positives = 260/557 (46%), Gaps = 9/557 (1%)
Query: 22 FLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIRYGLLILLVGVLNGVFSLAGR 81
F+I LI L S V VL++ ID GV+ G LL L + +
Sbjct: 652 FVIAALLIALDSAAGVGVLVLLQRGIDSGVAAGDMSTIGICALLALCLVAIGWCCYALQT 711
Query: 82 YLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRML 141
+AA+ + +R+ +F + R + + +K +L +R+T D + + RFL +
Sbjct: 712 IFAARAAESVQHTVRLRSFSHLLRLSLPWHEKHIDSRL-TRMTVDVDSLARFLQNGLASA 770
Query: 142 LYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYAMKVRPIYDKIRHQTGVIASI 201
SI ++ M ++ L + AL + +V+ Y P Y + R + G + S
Sbjct: 771 ATSIVTMVAIAAAMFWLDPILALTALSAVPVVILATWIYRRLSSPAYAQARLEIGKVNST 830
Query: 202 ATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMKITALYGNAPFLVL--GLAMS 259
++G++ ++S ++ + ++ + V+A K A+Y PFL A +
Sbjct: 831 LQEKVSGMRVVQSHGQQKQEAARLRALSDNFRATRVRAQKYLAVY--FPFLTFCTEAAYA 888
Query: 260 TMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDS 319
+ G + + +T G L AF + P++ L + Q++ A+ + ++ +
Sbjct: 889 AVLLIGATRVAEGEMTPGILAAFFLLLGQFYGPVQQLSGIVDSWQQATASGKHINALLAT 948
Query: 320 APKSIDPPDAVEISNPRGEIEFRDVWLTY-HTGRTVLKGVSFKVKPGEKVLITGPPGSGK 378
P ++ G + + Y + VL +S + PG V + G G+GK
Sbjct: 949 EETENIEPSSIT-PGTGGALRLEALTFRYPEKTQPVLDNLSLTIPPGTVVAVVGRSGAGK 1007
Query: 379 SSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKP 438
S+++KL+A Y P G++ + + + R+ V Q+ +F+ I ENI ++P
Sbjct: 1008 STLIKLLAGLYSPGSGQIRVGERLIDAASLSDYRRQTGLVTQDVALFSGDIAENIRYSRP 1067
Query: 439 NATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVL 498
+++ EVE AA+ A + + + LP G+ T V G LS GQRQ IALARA L I+L
Sbjct: 1068 DSSDTEVEIAARQAGLFETVQHLPLGFRTPVNNGGTDLSAGQRQLIALARAQLAQAHILL 1127
Query: 499 LDDPVSNLDAETEKKLVEDLKEI--LQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGK 556
LD+ + +D E++L+ L + + + ALIV+ RL+ + D ++V+ G I E G
Sbjct: 1128 LDEATARIDRSAEERLITSLTGVTHTEKRIALIVAHRLTTARRCDVIVVIDKGCIAEYGS 1187
Query: 557 PEELIKKGGIFSEMMKA 573
E+LI G+++ + +A
Sbjct: 1188 HEQLIAAHGLYARLWRA 1204
>gb|AAF73568.1| (AE002322) ABC transporter, ATP-binding protein [Chlamydia
muridarum]
Length = 647
Score = 208 bits (525), Expect = 1e-52
Identities = 145/516 (28%), Positives = 260/516 (50%), Gaps = 11/516 (2%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
L +++V +L R+L A LR D F A+Q M FF G L SR+
Sbjct: 127 LFLVVVAILKSTTLFFQRFLAQLIAIRVSCSLRKDYFLALQTLPMTFFHAHDMGNLSSRV 186
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIA--IVVGLNTTYA 181
D+ I L+ M+ Y I ++L +V ++I+ A + +A I++ A
Sbjct: 187 IADSSMIA--LAINALMVNYIQAPITMALALVVCLSISWKFCACVCLAFPILILPIIIVA 244
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
K++ + +I+ ++ + GI T+K E+ K+ Q+N+E+ L ++
Sbjct: 245 KKIKSLAKRIQKNQDHFTAVLLDFLLGILTVKVFRTEQFSFHKYCQKNDEIARLEERS-- 302
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGK-AIIQNTLTVGELVAFLTYMLTMMWPLRALGFTI 300
A Y P +L + F + + + + EL+ F + + P++
Sbjct: 303 --AAYSLIPRPLLHTIAALFFAFVVMIGLYKFHIPPEELIVFCGLLYLIYDPIKKFADEN 360
Query: 301 GDIQRSLAAASRLFDVIDSAPKSIDPPDAV-EISNPRGEIEFRDVWLTYHTGRTVLKGVS 359
I R AAA R ++V+D + + + + E + I+F +V Y VL +
Sbjct: 361 ATIMRGCAAAERFYEVLDLSKQQTTVSEQLNEFQGLQHSIQFCNVSFGYSEDSLVLSDFN 420
Query: 360 FKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVP 419
+K GE + I GP GSGKS+I KL+ R Y+ ++GE+L+D + + +LRK + V
Sbjct: 421 LVLKKGEAIGIVGPTGSGKSTIAKLLPRLYEISQGELLVDSLPITSYSKNSLRKHIGCVL 480
Query: 420 QEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGG 479
Q+PF+F +I N+ + + ++EEV + K ++ ++F+ +P+G +++ E G LSGG
Sbjct: 481 QQPFLFYDTIWNNLTCGR-DFSEEEVFESLKQSRAYEFVCKMPQGVHSLLEESGKNLSGG 539
Query: 480 QRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKL 539
Q+QR+ +ARA+L N I+LLD+ S+LDA +E + E + ++ T +I++ +LS ++
Sbjct: 540 QQQRLTIARALLHNTSILLLDEATSSLDAISENYIKEMVGKLKGRCTQIIIAHKLSTLEY 599
Query: 540 VDRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGG 575
VDR++ ++ GK + +G EEL+ F M G
Sbjct: 600 VDRIVYLEQGKKIAEGTKEELLVSCPAFQRMWVLSG 635
>pir||H83243 probable ATP-binding/permease fusion ABC transporter PA3228
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9949349|gb|AAG06616.1|AE004745_13 (AE004745)
probable ATP-binding/permease fusion ABC transporter
[Pseudomonas aeruginosa]
Length = 610
Score = 206 bits (518), Expect = 7e-52
Identities = 141/503 (28%), Positives = 244/503 (48%), Gaps = 31/503 (6%)
Query: 95 LRMDAFRAIQRHEMEFFDKTFSGQLISRITNDTERITRFLSFRVRMLLYSIFLIIISLYY 154
+R R + + + FF F+G++ RI + V L + + + +L
Sbjct: 118 IRWQNHRYVLKQSLGFFQNDFAGRIAQRIMQTGNSLRDSAVQVVDALWHVLIYTVSALVL 177
Query: 155 MVRMNITLTMVALITIAIVVGLNTTYAMKV-RPIYDKIRHQTGVIASIATG--TIAGIKT 211
+ L + ++ + VG + +V R + ++ ++ I G I +K
Sbjct: 178 FAEADWRLMIPLVLWVFAYVGALAYFVPQVKRRSVEASDSRSKLMGRIVDGYTNITTLKL 237
Query: 212 IKSLSVEENV-------QTKFSQENEELYSLNVKAMKITALYGNAPFLVLGLAMSTMFYY 264
EE+ QT SQ + V +M +T N L+ G ++ +
Sbjct: 238 FAHTRQEEDYAREAIGDQTLKSQRAGRV----VTSMDVTITVMNG-VLITGTTGLALWLW 292
Query: 265 GGKAIIQNT--LTVGELVAFLTYMLTMMWPLRALGFTIGDIQRSLAAASRLFDVIDSAPK 322
+ I L G ++ +MW + + IG +Q + I K
Sbjct: 293 SQELISVGAIALATGLVIRINNMSGWIMWVVGGIFENIGQVQDGM-------QTIALPRK 345
Query: 323 SIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFKVKPGEKVLITGPPGSGKSSIL 382
+D DA + RGE+EF + Y G V++G+ KV+PGEK+ + GP G+GKS+++
Sbjct: 346 VVDREDAQPLRVERGEVEFEHIAFHYGKGSGVIQGLDLKVRPGEKIGLVGPSGAGKSTLV 405
Query: 383 KLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQ 442
L+ R Y G +L+DG ++A + E+LR + V Q+ + +RSIR+N+ +P A+
Sbjct: 406 NLLLRLYDLESGRILVDGQDIAGVTQESLRAQIGMVTQDTSLLHRSIRDNLLYGRPGASD 465
Query: 443 EEVERAAKIAKIHDFIASLP-----KGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIV 497
E+ A + A+ +FI L +G+D VGE+G+ LSGGQRQRIA+AR +L + I+
Sbjct: 466 AELMEAVRKARADEFIPLLSDAEGRRGFDAHVGERGVKLSGGQRQRIAIARVLLKDAPIL 525
Query: 498 LLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKIVEDGKP 557
+LD+ S LD+E E + E L+ ++Q KT + ++ RLS + +DR++V+ G I E G
Sbjct: 526 ILDEATSALDSEVESAIQESLETLMQGKTVIAIAHRLSTIARMDRLVVLDKGHIAESGTH 585
Query: 558 EELIKKGGIFSEMM--KAGGVYG 578
EL+ GG+++ + + GG G
Sbjct: 586 AELLAHGGLYARLWQHQTGGFVG 608
>pir||E71536 probable transport ATP binding protein - Chlamydia trachomatis
(serotype D, strain UW3/Cx) >gi|3328676|gb|AAC67857.1|
(AE001299) Transport ATP Binding Protein [Chlamydia
trachomatis]
Length = 646
Score = 203 bits (512), Expect = 3e-51
Identities = 145/515 (28%), Positives = 254/515 (49%), Gaps = 9/515 (1%)
Query: 64 LLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLISRI 123
L +++V +L R+L A LR D F A+Q M FF G L SR+
Sbjct: 127 LFLVVVAILKSTTLFFQRFLAQLIAIRVSCSLRKDYFLALQTLPMTFFHAHDMGNLSSRV 186
Query: 124 TNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLN--TTYA 181
D+ I L+ M+ Y I ++L +V ++I+ A + +A + + A
Sbjct: 187 IADSSMIA--LAINALMVNYIQAPITMTLALVVCLSISWKFCACVCLAFPIFILPIVIIA 244
Query: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
KV+ + +I+ A+ + GI T+K E+ +K+ Q+N+E+ L ++
Sbjct: 245 KKVKALAKRIQKSQDHSAAALLDFLLGILTVKVFRTEQFSFSKYCQKNDEIARLEERSAA 304
Query: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
+ + + L + + G + + ELV F + + P++
Sbjct: 305 YSLIPRPLLHTIASLFFALVIMIG---LYHFHIPPEELVVFCGLLYLIYDPIKKFADENA 361
Query: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAV-EISNPRGEIEFRDVWLTYHTGRTVLKGVSF 360
+I AAA R ++V+D A + + + + E + I+F +V Y VL +
Sbjct: 362 NIMWGCAAAERFYEVLDLAKQQSNVSEKLNEFQGLQHSIQFCNVSFGYVEDSPVLSDFNL 421
Query: 361 KVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQ 420
+K GE + I GP GSGKS+I KL+ R Y+ + GE+LID + + +LRK + V Q
Sbjct: 422 VLKKGEAIGIVGPTGSGKSTIAKLLPRLYEVSHGELLIDSLPIRSYCKNSLRKHIGCVLQ 481
Query: 421 EPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQ 480
PF+F ++ N+ + ++EEV A K A ++F++ +P+G +++ E LSGGQ
Sbjct: 482 HPFLFYDTVWNNLTCGR-TFSEEEVFHALKQAHAYEFVSKMPQGVHSLLEESSKNLSGGQ 540
Query: 481 RQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLV 540
+QR+ +ARA+L N I+LLD+ S LDA +E + E + ++ T +I++ +LS ++ V
Sbjct: 541 QQRLTIARALLHNTSILLLDEATSALDAISENYVKEIVGQLKGRCTQIIIAHKLSTLEYV 600
Query: 541 DRVIVMKDGKIVEDGKPEELIKKGGIFSEMMKAGG 575
DR++ ++ GK + +G EEL+ F M G
Sbjct: 601 DRIVYLEQGKKIAEGTKEELLDSCPAFQRMWVLSG 635
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.323 0.140 0.387
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 192645304
Number of Sequences: 2977
Number of extensions: 7643216
Number of successful extensions: 38728
Number of sequences better than 1.0e-10: 2276
Number of HSP's better than 0.0 without gapping: 742
Number of HSP's successfully gapped in prelim test: 1536
Number of HSP's that attempted gapping in prelim test: 32785
Number of HSP's gapped (non-prelim): 2903
length of query: 579
length of database: 189,106,746
effective HSP length: 59
effective length of query: 520
effective length of database: 153,796,013
effective search space: 79973926760
effective search space used: 79973926760
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 167 (69.5 bits)