BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2148 (PAB2148) DE:ABC TRANSPORTER ATP-BINDING PROTEIN
(580 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75142 abc transporter ATP-binding protein PAB2148 - Pyroco... 1121 0.0
pir||B71182 probable ABC transporter ATP-binding protein - Pyroc... 997 0.0
sp|Q9WYC4|Y288_THEMA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 442 e-123
dbj|BAA96814.1| (AB040146) ABC transporter B [Thermus thermophilus] 411 e-114
sp|P54719|YFIC_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 397 e-109
pir||S72638 hypothetical ABC exporter component B - Thermoanaero... 372 e-102
pir||A69858 ABC transporter (ATP-binding protein) homolog yknV -... 369 e-101
dbj|BAB04845.1| (AP001511) ABC transporter (ATP-binding protein)... 369 e-101
dbj|BAB04534.1| (AP001509) ABC transporter (ATP-binding protein)... 367 e-100
gb|AAK43114.1| ABC transporter, ATP binding protein [Sulfolobus ... 361 1e-98
pir||G69815 ABC transporter (ATP-binding protein) homolog ygaD -... 361 1e-98
pir||G75321 ABC transporter, ATP-binding protein, MsbA family - ... 360 2e-98
emb|CAB69752.1| (AL137187) putative ABC transporter [Streptomyce... 350 3e-95
pir||C71182 probable ABC transporter ATP-binding protein - Pyroc... 346 4e-94
sp|Q11047|YC72_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 344 2e-93
dbj|BAB04844.1| (AP001511) ABC transporter (ATP-binding protein)... 339 5e-92
gb|AAD01950.1| (AF033015) ABC transporter homolog Z [Listeria mo... 339 7e-92
emb|CAB66302.1| (AL136519) ABC transporter protein, ATP-binding ... 338 9e-92
pir||G75142 abc transporter, ATP-binding protein PAB2147 - Pyroc... 337 2e-91
dbj|BAB06054.1| (AP001515) ABC transporter (ATP-binding protein)... 335 1e-90
dbj|BAB10828.1| (AB016892) ABC transporter-like protein [Arabido... 333 2e-90
gb|AAF67494.1|AF170880_1 (AF170880) NovA [Streptomyces spheroides] 331 2e-89
emb|CAC13096.1| (AL445503) putative ABC transporter ATP-binding ... 329 6e-89
pir||S77459 ABC-type transport protein slr1149 - Synechocystis s... 326 5e-88
pir||H69857 ABC transporter (ATP-binding protein) homolog yknU -... 322 8e-87
gb|AAF71763.1|AF263912_2 (AF263912) NysG [Streptomyces noursei] 320 3e-86
pir||H72425 ABC transporter, ATP-binding protein - Thermotoga ma... 319 4e-86
dbj|BAB04877.1| (AP001511) ABC transporter (ATP-binding protein)... 319 5e-86
dbj|BAB04660.1| (AP001510) ABC transporter (ATP-binding protein)... 317 2e-85
pir||H69828 ABC transporter (ATP-binding protein) homolog yheH -... 316 3e-85
pir||A75590 ABC transporter, ATP-binding protein - Deinococcus r... 315 8e-85
pir||S75806 hemolysin secretion protein hlyB - Synechocystis sp.... 312 7e-84
dbj|BAB04432.1| (AP001509) ABC transporter (ATP-binding protein)... 310 3e-83
sp|P55469|Y4GM_RHISN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEI... 308 1e-82
emb|CAB76004.1| (AL157916) putative ABC transporter [Streptomyce... 305 1e-81
dbj|BAB07610.1| (AP001520) ABC transporter (ATP-binding protein)... 304 1e-81
pir||D70031 ABC transporter (ATP-binding protein) homolog yvcC -... 303 4e-81
gb|AAG11416.1|AF263455_1 (AF263455) TagA [Dictyostelium discoideum] 302 7e-81
sp|Q03727|COMA_STRPN TRANSPORT ATP-BINDING PROTEIN COMA >gi|5207... 302 1e-80
pir||A39203 comA protein - Streptococcus pneumoniae 300 2e-80
pir||A75282 ABC transporter, ATP-binding protein, MsbA family - ... 300 4e-80
pir||A75554 ABC transporter, ATP-binding protein, MsbA family - ... 300 4e-80
pir||G70837 probable ABC transporter Rv0194 - Mycobacterium tube... 298 1e-79
pir||S77337 ABC-type transport protein sll1725 - Synechocystis s... 296 4e-79
dbj|BAA92038.1| (AK002018) unnamed protein product [Homo sapiens] 295 7e-79
gb|AAG18746.1| (AE004979) ABC transport protein; Trp1 [Halobacte... 294 2e-78
gi|6005804 ATP-binding cassette, sub-family B, member 8; mitocho... 293 4e-78
sp|P45861|YWJA_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 293 5e-78
gb|AAB88659.1| (U62935) multidrug resistance protein 2 [Aspergil... 290 3e-77
emb|CAA62898.1| (X91786) ATP-binding cassette transporter A [Sta... 289 4e-77
gb|AAF45509.1| (AE003417) EG:171D11.2 gene product [Drosophila m... 289 4e-77
dbj|BAB04876.1| (AP001511) ABC transporter (ATP-binding protein)... 289 4e-77
gi|11425328 ATP-binding cassette, sub-family B, member 10 [Homo ... 289 4e-77
pir||T13416 hypothetical protein 171D11.2 - fruit fly (Drosophil... 289 5e-77
gi|9961244 ATP-binding cassette, sub-family B, member 10 [Homo s... 289 7e-77
gb|AAG15222.1|AF288462_2 (AF288462) AbcA [Chloroflexus aurantiacus] 287 2e-76
sp|P47261|Y015_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 287 2e-76
pir||E82539 ABC transporter ATP-binding protein XF2582 [imported... 287 2e-76
sp|P75094|Y015_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 287 3e-76
dbj|BAA97990.2| (AB045382) TAPL [Mus musculus] 287 3e-76
gi|11560034 TAP-like ABC transporter [Rattus norvegicus] >gi|604... 287 3e-76
gi|9955966 ATP-binding cassette, sub-family B, member 9, isoform... 286 4e-76
gi|9845230 ATP-binding cassette, sub-family B, member 9 [Mus mus... 286 4e-76
gb|AAF48177.1| (AE003489) CG1824 gene product [Drosophila melano... 286 4e-76
pir||B83022 transport protein MsbA PA4997 [imported] - Pseudomon... 284 1e-75
dbj|BAB06055.1| (AP001515) ABC transporter (ATP-binding protein)... 284 1e-75
pir||T36183 probable ABC-type transport protein - Streptomyces c... 284 2e-75
pir||JC4554 ABC-type transporter homolog - Staphylococcus aureus... 283 4e-75
gb|AAB37564.1| (U40139) ComA [Streptococcus gordonii] 282 9e-75
pir||S72637 hypothetical ABC exporter component A - Thermoanaero... 281 1e-74
dbj|BAB04170.1| (AP001508) lantibiotic mersacidin transporter sy... 281 1e-74
emb|CAB88985.1| (AL353864) putative ABC-transport protein. [Stre... 281 1e-74
pir||I56273 ATP-dependent transport protein SapT - Lactobacillus... 281 2e-74
gb|AAB49750.1| (U63741) multidrug resistance protein LmrA [Lacto... 279 5e-74
emb|CAA64189.1| (X94434) ABC-transporter PlnG [Lactobacillus pla... 279 6e-74
gi|9506367 ATP-binding cassette, sub-family B, member 12; Abc-mi... 279 8e-74
pir||T27215 hypothetical protein Y57G11C.1 - Caenorhabditis eleg... 278 1e-73
gb|AAB52482.1| (U97407) Contains similarity to Pfam domain: PF00... 278 1e-73
gb|AAD53033.1|AF115536_1 (AF115536) TAP1 protein [Oncorhynchus m... 277 2e-73
gb|AAG28766.1|AF300457_4 (AF300457) CoaD [Bacillus coagulans] 277 3e-73
emb|CAB60586.1| (AL117200) contains similarity to Pfam domain: P... 276 4e-73
pir||S58356 pepT protein - Staphylococcus epidermidis >gi|212659... 276 4e-73
sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 276 4e-73
pir||T31617 hypothetical protein Y50E8A.m - Caenorhabditis elegans 276 4e-73
gb|AAD29140.1|AF099088_9 (AF099088) EntT [Enterococcus faecium] 275 1e-72
gb|AAC44070.1| (U51197) unknown [Sphingomonas sp. S88] 275 1e-72
gb|AAF15371.1|U66588_3 (U66588) PaxB [Pasteurella aerogenes] 273 3e-72
sp|P08716|HLYB_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, PL... 273 4e-72
gb|AAG26952.1|AC069471_13 (AC069471) P-glycoprotein, putative [A... 273 5e-72
pir||LEECB hemolysin secretion protein hlyB - Escherichia coli >... 272 6e-72
emb|CAB05917.1| (Z83327) transport-associated protein [Salmo salar] 272 6e-72
gb|AAD55753.1|AF108387_1 (AF108387) transporter associated with ... 272 8e-72
sp|P36497|PEDD_PEDAC PEDIOCIN PA-1 TRANSPORT ATP-BINDING PROTEIN... 272 1e-71
dbj|BAA96813.1| (AB040146) ABC transporter A [Thermus thermophilus] 271 1e-71
sp|P10089|HLY2_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, CH... 271 2e-71
sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA... 270 2e-71
sp|Q00564|LCNC_LACLA LACTOCOCCIN A TRANSPORT ATP-BINDING PROTEIN... 270 2e-71
pir||S75352 ABC-type transport protein slr2019 - Synechocystis s... 270 2e-71
sp|P23702|HLYB_ACTAC LEUKOTOXIN SECRETION ATP-BINDING PROTEIN >g... 270 4e-71
pir||S51777 xIIIB protein - Actinobacillus pleuropneumoniae >gi|... 270 4e-71
pir||C30169 leukotoxin expression protein B - Pasteurella haemol... 269 5e-71
sp|P16532|HLYB_PASHA LEUKOTOXIN SECRETION ATP-BINDING PROTEIN >g... 269 5e-71
pir||E72396 ABC transporter, ATP-binding protein - Thermotoga ma... 269 5e-71
gb|AAB81307.1| (L47121) ATP-dependent translocator [Carnobacteri... 269 7e-71
gb|AAB40205.1| (U82664) multidrug resistance-like ATP-binding pr... 268 9e-71
sp|P75706|MDLB_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 268 9e-71
gb|AAD55751.1|AF108385_1 (AF108385) transporter associated with ... 268 9e-71
pir||S57913 probable translocation protein sppT, ATP-dependent -... 268 2e-70
pir||C49219 toxin apxIII secretion protein apxIIIB - Actinobacil... 267 2e-70
sp|Q04473|RT3B_ACTPL RTX-III TOXIN DETERMINANT B (TOXIN RTX-III ... 267 2e-70
pir||A69829 ABC transporter (ATP-binding protein) homolog yheI -... 267 2e-70
sp|P11599|HLYB_PROVU HEMOLYSIN SECRETION ATP-BINDING PROTEIN >gi... 267 3e-70
gb|AAA25544.1| (M24197) leukotoxin (LktB) [Pasteurella haemolytica] 267 3e-70
emb|CAA11805.1| (AJ224003) ATP-dependent transporter [Carnobacte... 267 3e-70
gb|AAF23810.1|AF213822_25 (AF213822) inner membrane ABC transpor... 267 3e-70
gb|AAD21059.1| (AF119150) RtxB protein [Vibrio cholerae] 266 5e-70
pir||H82198 RTX toxin transporter VC1448 [imported] - Vibrio cho... 266 5e-70
sp|P26760|RT1B_ACTPL RTX-I TOXIN DETERMINANT B (TOXIN RTX-I SECR... 266 6e-70
emb|CAA60043.1| (X86087) EHEC-hlyB [Escherichia coli] 266 6e-70
pir||T31072 heterocyst differentiation protein HetC - Anabaena s... 266 6e-70
gi|10955284 Hemolysin B [Escherichia coli] >gi|7442681|pir||T002... 266 6e-70
dbj|BAA93709.1| (AB032930) hemolysin B [Escherichia coli] 266 6e-70
pir||T06165 multidrug resistance protein 1 homolog - barley >gi|... 265 8e-70
emb|CAA08835.1| (AJ009799) ABC transporter protein [Gallus gallus] 265 8e-70
pir||C81352 lipid export ABC transport protein Cj0803 [imported]... 265 8e-70
pir||E70435 ABC transporter (MsbA subfamily) - Aquifex aeolicus ... 265 1e-69
pir||E82561 toxin secretion ABC transporter ATP-binding protein ... 264 2e-69
pir||T04251 P-glycoprotein 2 - Arabidopsis thaliana >gi|2108252|... 263 3e-69
gb|AAA75000.1| (U17608) multidrug resistance protein [Xenopus la... 263 4e-69
pir||S55692 multidrug resistance protein homolog (mdr) - African... 263 4e-69
pir||F82198 probable toxin secretion transporter VC1446 [importe... 263 5e-69
gb|AAD10836.1| (U52079) P-glycoprotein [Solanum tuberosum] 262 7e-69
dbj|BAB02855.1| (AB026644) multidrug resistance p-glycoprotein; ... 262 7e-69
pir||B83507 probable ATP-binding/permease fusion ABC transporter... 262 7e-69
sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA... 262 9e-69
pir||T34038 hypothetical protein F43E2.4 - Caenorhabditis elegan... 262 9e-69
pir||T17482 ABC-type transport protein homolog - Amycolatopsis o... 262 9e-69
sp|P55122|HLYB_PASSP LEUKOTOXIN SECRETION ATP-BINDING PROTEIN >g... 261 2e-68
gb|AAF18148.1|AF207838_7 (AF207838) ABC transporter CbaT [Carnob... 261 2e-68
pir||A71943 multi-drug resistance protein - Helicobacter pylori ... 261 2e-68
gi|4502457 ATP-binding cassette, sub-family B (MDR/TAP), member ... 260 3e-68
pir||T32865 hypothetical protein ZK484.2 - Caenorhabditis elegan... 260 3e-68
dbj|BAB02854.1| (AB026644) multidrug resistance p-glycoprotein; ... 260 3e-68
dbj|BAB02858.1| (AB026644) multidrug resistance p-glycoprotein; ... 260 3e-68
pir||I39646 secretion protein B - Actinobacillus pleuropneumonia... 259 6e-68
gb|AAG26946.1|AC069471_7 (AC069471) P-glycoprotein, putative [Ar... 259 6e-68
gi|11430459 ATP-binding cassette, sub-family B (MDR/TAP), member... 259 6e-68
pir||T31073 multidrug resistance p-glycoprotein - nematode (Haem... 259 8e-68
gb|AAD22645.1|AC007138_9 (AC007138) putative P-glycoprotein-like... 259 8e-68
gb|AAD28285.1|AF136523_1 (AF136523) bile salt export pump [Homo ... 259 8e-68
pir||B64655 multidrug resistance protein - Helicobacter pylori (... 258 1e-67
gb|AAG01549.1|AF291822_1 (AF291822) multidrug resistance protein... 257 2e-67
dbj|BAB02129.1| (AP000386) P-glycoprotein; multi-drug resistance... 257 2e-67
pir||A35391 hetA protein - Anabaena sp 257 3e-67
sp|P22638|HEPA_ANASP HETEROCYST DIFFERENTIATION ATP-BINDING PROT... 257 3e-67
gb|AAB88657.1| (U62933) multidrug resistance protein 1 [Aspergil... 257 3e-67
gb|AAF23176.1|AF216497_1 (AF216497) P-glycoprotein [Gossypium hi... 257 3e-67
pir||T40790 probable permease - fission yeast (Schizosaccharomyc... 256 4e-67
gi|11038656 ATP-binding cassette, sub-family B, member 11; bile ... 256 4e-67
dbj|BAB02852.1| (AB026644) multidrug resistance p-glycoprotein; ... 256 4e-67
pir||T30293 ABC transport protein homolog - Salmonella typhi >gi... 254 1e-66
gb|AAD43626.1|AF071411_1 (AF071411) multidrug resistance protein... 254 2e-66
gi|9955968 ATP-binding cassette, sub-family B, member 9, isoform... 254 2e-66
pir||A40366 hemolysin secretion protein appB - Actinobacillus pl... 253 3e-66
emb|CAB69672.1| (AL137165) probable ABC transporter protein, ATP... 253 3e-66
pir||D82146 transport ATP-binding protein MsbA VC1878 [imported]... 253 4e-66
gb|AAG25076.1|AF273216_1 (AF273216) ABC transporter RzcB [Rhizob... 253 4e-66
sp|P18770|CYAB_BORPE CYCLOLYSIN SECRETION ATP-BINDING PROTEIN CY... 252 6e-66
pir||C72275 ABC transporter, ATP-binding protein - Thermotoga ma... 252 6e-66
pir||T42842 bile salt transport protein, ATP-dependent - rat >gi... 251 1e-65
pir||T42228 P-glycoprotein sister - rat >gi|3273484|gb|AAC24753.... 251 1e-65
pir||B71676 probable ABC transporter msbA2 - Rickettsia prowazek... 251 1e-65
sp|P77265|MDLA_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 250 3e-65
gb|AAF17668.1|AC009398_17 (AC009398) F20B24.12 [Arabidopsis thal... 250 3e-65
pir||S30327 multidrug resistance protein 1 - Entamoeba histolyti... 249 5e-65
sp|P57551|MDLA_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 249 7e-65
gb|AAB51079.1| (L40491) leucocin A translocator [Leuconostoc gel... 249 9e-65
sp|Q10418|MESD_LEUME MESENTERICIN Y105 TRANSPORT ATP-BINDING PRO... 248 1e-64
gb|AAA91199.1| (L76468) ABC-transporter [Gorilla gorilla] 247 2e-64
gb|AAA91198.1| (L76470) ABC-transporter [Gorilla gorilla] 247 3e-64
gb|AAC12903.1| (L21205) peptide transporter [Homo sapiens] >gi|3... 247 3e-64
gb|AAC72031.1| (AF047554) putative ABC transporter [Myxococcus x... 245 7e-64
dbj|BAA96612.1| (AP002482) Similar to Arabidopsis thaliana chrom... 245 7e-64
dbj|BAB13177.1| (AP001119) mdlB [Buchnera sp. APS] 245 7e-64
sp|P57552|MDLB_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTE... 245 7e-64
pir||T03514 probable secretion ATP-binding protein - Rhodobacter... 245 1e-63
pir||I84547 mdl protein - Escherichia coli >gi|146801|gb|AAC3687... 245 1e-63
gb|AAC12905.1| (L21207) peptide transporter [Homo sapiens] 245 1e-63
pir||T23476 hypothetical protein K08E7.9 - Caenorhabditis elegan... 245 1e-63
sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 244 2e-63
gb|AAC12906.1| (L21208) peptide transporter [Homo sapiens] 244 2e-63
gb|AAA20681.1| (L16958) Mdl1p [Saccharomyces cerevisiae] 243 3e-63
gb|AAF09091.1|AC011663_27 (AC011663) putative ABC transporter; 8... 243 5e-63
pir||H81855 probable cytolysin secretion ABC transporter NMA1620... 243 5e-63
pir||H81088 ABC transporter family protein NMB1400 [imported] - ... 242 6e-63
gb|AAF58271.1| (AE003815) Mdr50 gene product [Drosophila melanog... 242 8e-63
gb|AAA93553.1| (L23922) P-glycoprotein 5 [Entamoeba histolytica] 242 1e-62
pir||T28151 probable ABC-type transport protein TAP2 - chicken >... 242 1e-62
emb|CAB60262.1| (AJ250862) MrsT protein [Bacillus sp. HIL-Y85/54... 242 1e-62
pir||T31078 probable ABC-transporter TycE - Brevibacillus brevis... 241 2e-62
pir||T30882 multidrug resistance protein 1 - Aspergillus flavus ... 240 3e-62
pir||S30328 multidrug resistance protein 2 - Entamoeba histolyti... 240 4e-62
gi|6323217 ATP-binding cassette (ABC) transporter family member;... 239 6e-62
pir||T43261 multidrug resistance protein 1 - fungus (Filobasidiu... 239 6e-62
pir||JE0248 ATP-binding cassette half-transporter - rat >gi|2982... 239 6e-62
pir||T14805 hypothetical protein F15J5.20 - Arabidopsis thaliana... 239 6e-62
emb|CAB78807.1| (AL161547) multidrug resistance protein/P-glycop... 239 6e-62
pir||F82726 ABC transporter ATP-binding protein XF1081 [imported... 239 7e-62
gi|11419475 ATP-binding cassette, sub-family B, member 8 [Homo s... 239 7e-62
sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49 (P-... 238 2e-61
gb|AAF58437.1| (AE003820) Mdr49 gene product [Drosophila melanog... 238 2e-61
pir||S74455 ABC-type transport protein slr1488 - Synechocystis s... 237 2e-61
pir||G71731 mitochondrial transporter atm1 precursor (atm1) RP20... 237 2e-61
dbj|BAA34383.1| (AB019513) ABC transporter [Streptomyces coelico... 237 2e-61
pir||F82939 transport ATP-binding protein UU060 [imported] - Ure... 237 2e-61
gb|AAF65552.1|AF249879_1 (AF249879) liver bile salt export pump ... 237 2e-61
gb|AAA16186.1| (L07065) P-glycoprotein/multidrug resistance prot... 236 6e-61
pir||A47377 multidrug resistance protein Mdr50 - fruit fly (Dros... 236 6e-61
emb|CAB88932.1| (AL353863) putative ABC transporter [Streptomyce... 236 6e-61
emb|CAB69751.1| (AL137187) putative ABC transporter [Streptomyce... 233 6e-60
gb|AAD49436.1|AF083642_1 (AF083642) P-glycoprotein [Onchocerca v... 231 2e-59
dbj|BAA83673.1| (AB007195) TAP2 [Coturnix japonica] 231 2e-59
pir||T26313 hypothetical protein W09D6.6 - Caenorhabditis elegan... 230 3e-59
emb|CAA71281.1| (Y10232) Tap1 protein [Rattus norvegicus] 229 5e-59
gb|AAC72026.1| (AF043280) ABC transporter [Streptococcus salivar... 229 5e-59
gb|AAF47525.1| (AE003472) CG7955 gene product [alt 3] [Drosophil... 229 5e-59
emb|CAA40742.1| (X57523) mtp1 [Rattus norvegicus] 229 6e-59
sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) >gi|1115... 229 6e-59
pir||T19982 hypothetical protein C47A10.1 - Caenorhabditis elega... 229 8e-59
emb|CAA71282.1| (Y10233) Tap1 protein [Rattus norvegicus] 228 1e-58
emb|CAA71284.1| (Y10235) Tap1 protein [Rattus norvegicus] 227 3e-58
gb|AAF55241.1| (AE003710) CG4225 gene product [Drosophila melano... 227 3e-58
emb|CAA71279.1| (Y10230) Tap1 protein [Rattus norvegicus] >gi|17... 226 4e-58
gb|AAF71764.1|AF263912_3 (AF263912) NysH [Streptomyces noursei] 225 1e-57
gb|AAD10394.1| (U46488) NrpB [Proteus mirabilis] 224 2e-57
gb|AAF04885.1|AC010796_21 (AC010796) putative ABC transporter; 7... 224 2e-57
gb|AAB00463.1| (L26955) transport protein [Streptomyces verticil... 223 4e-57
gb|AAF73656.1| (AE002196) ABC transporter, ATP-binding protein [... 222 8e-57
gi|9961246 ATP-binding cassette, sub-family B, member 3, isoform... 222 1e-56
dbj|BAA96918.1| (AB019228) ABC transporter-like protein [Arabido... 222 1e-56
gi|11417922 ATP-binding cassette, sub-family B, member 3, isofor... 221 1e-56
emb|CAA80522.1| (Z22935) TAP2B [Homo sapiens] 221 1e-56
emb|CAA80523.1| (Z22936) TAP2E [Homo sapiens] 221 1e-56
gb|AAF64672.1|AF218367_1 (AF218367) ABC transporter protein [Bru... 221 1e-56
pir||I38528 ABC transport protein - human (fragment) >gi|533092|... 221 2e-56
emb|CAA88940.2| (Z49126) contains similarity to Pfam domain: PF0... 221 2e-56
emb|CAB97048.1| (AJ272202) mitochondrial half-ABC transporter [A... 220 4e-56
pir||T47045 hypothetical protein ybtP [imported] - Yersinia pest... 219 7e-56
gb|AAA86666.1| (L36248) ATP-binding cassette protein [Fasciola h... 218 1e-55
emb|CAA94219.2| (Z70268) Similarity to C.elegans p-glycoprotein ... 218 2e-55
pir||T25082 hypothetical protein T21E8.2 - Caenorhabditis elegans 218 2e-55
pir||T17437 ybtP protein - Yersinia pestis >gi|3818602|gb|AAC695... 217 2e-55
emb|CAB46573.1| (AJ132668) lipoprotein inner membrane ABC-transp... 214 2e-54
emb|CAB76005.1| (AL157916) putative ABC transporter [Streptomyce... 214 2e-54
pir||S60182 ATP-binding transport protein exsA - Rhizobium melil... 214 2e-54
dbj|BAA96370.1| (AB035331) ABC protein [Physarum polycephalum] 214 2e-54
gb|AAD47014.1|AF147744_4 (AF147744) transporter [Staphylococcus ... 212 9e-54
sp|P22520|CVAB_ECOLI COLICIN V SECRETION ATP-BINDING PROTEIN CVA... 208 1e-52
gb|AAD43625.1|AF071410_1 (AF071410) ATP-binding cassette multidr... 208 1e-52
gb|AAD25925.1|AF082072_1 (AF082072) ABC transporter protein AtrC... 208 1e-52
gb|AAG32538.1| (AY005472) SalT [Streptococcus salivarius] 205 2e-51
gi|9961248 ATP-binding cassette, sub-family B, member 3, isoform... 204 3e-51
gb|AAD31384.1|AF078671_1 (AF078671) transporter 2 isoform [Homo ... 203 3e-51
gi|10957146 cytolysin B transport protein [Lactococcus lactis] >... 202 8e-51
emb|CAA94220.2| (Z70268) Similarity to C.elegans p-glycoprotein ... 201 2e-50
pir||T25083 hypothetical protein T21E8.1 - Caenorhabditis elegans 201 2e-50
sp|Q11046|YC73_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 200 3e-50
pir||T43469 hypothetical protein DKFZp434L0827.1 - human (fragme... 199 7e-50
dbj|BAA92227.1| (AK000002) FLJ00002 protein [Homo sapiens] 199 7e-50
dbj|BAB15736.1| (AK024446) FLJ00036 protein [Homo sapiens] 199 7e-50
pir||F83539 probable ATP-binding/permease fusion ABC transporter... 197 3e-49
gi|11435376 ATP-binding cassette, sub-family C, member 4 [Homo s... 196 4e-49
gi|5031915 ATP-binding cassette, sub-family C, member 4; canalic... 195 1e-48
gb|AAC27077.1| (AF071203) ABC transporter MOAT-B isoform [Homo s... 195 1e-48
gb|AAA88774.1| (U47048) MtfB [Escherichia coli] 194 2e-48
gb|AAF54656.1| (AE003692) CG14709 gene product [Drosophila melan... 194 2e-48
emb|CAA72120.1| (Y11250) multi resistance protein [Arabidopsis t... 189 6e-47
pir||T00961 hypothetical protein F20D22.11 - Arabidopsis thalian... 189 6e-47
gb|AAF53736.2| (AE003661) CG17338 gene product [Drosophila melan... 189 1e-46
pir||T18940 multidrug resistance protein homolog - Caenorhabditi... 186 5e-46
gb|AAG28288.1|AC025295_8 (AC025295) ABC transporter, putative [A... 186 5e-46
gb|AAA79094.1| (U35123) p-glycoprotein [Urechis caupo] 184 2e-45
pir||B71696 probable transport ATP-binding protein msbA (msbA1) ... 183 6e-45
gb|AAF61810.1| (AF129811) unknown [Moraxella catarrhalis] 182 7e-45
gb|AAC43673.1| (U21919) ATP-coupled transporter [Brucella abortu... 182 1e-44
gb|AAF53950.1| (AE003668) CG9270 gene product [Drosophila melano... 182 1e-44
gb|AAC97164.1| (AF027405) SapD [Campylobacter fetus] >gi|4019201... 177 3e-43
sp|P13568|MDR_PLAFF MULTIDRUG RESISTANCE PROTEIN (CHLOROQUINE RE... 176 4e-43
gb|AAF71750.1|AF258325_1 (AF258325) multidrug resistance protein... 176 4e-43
emb|CAA05625.1| (AJ002584) AtMRP4 [Arabidopsis thaliana] >gi|373... 176 6e-43
sp|Q52402|AARD_PROST TRANSPORT ATP-BINDING PROTEIN AARD >gi|7445... 175 1e-42
gi|6321720 Yor1p [Saccharomyces cerevisiae] >gi|1730876|sp|P5304... 175 1e-42
dbj|BAB01717.1| (AB023045) multidrug resistance-associated prote... 175 2e-42
gi|6322640 ABC transporter, glycoprotein, component of a-factor ... 173 5e-42
prf||1512309A multidrug resistance P glycoprotein [Saccharomyces... 173 5e-42
pir||T48059 ABC transporter-like protein - Arabidopsis thaliana ... 173 6e-42
sp|P54683|TAGB_DICDI PRESTALK-SPECIFIC PROTEIN TAGB PRECURSOR >g... 170 3e-41
gi|7304851 ATP-binding cassette, sub-family C, member 5a [Mus mu... 167 3e-40
sp|Q23868|TAGC_DICDI PRESTALK-SPECIFIC PROTEIN TAGC PRECURSOR >g... 167 4e-40
gb|AAF56312.1| (AE003748) CG5789 gene product [Drosophila melano... 166 5e-40
pir||T14886 leukotoxin expression protein B homolog - Salmonella... 166 6e-40
sp|Q9QYM0|MRP5_RAT MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 >gi... 166 6e-40
sp|P29018|CYDD_ECOLI TRANSPORT ATP-BINDING PROTEIN CYDD >gi|7445... 166 8e-40
gi|5032101 ATP-binding cassette, sub-family C (CFTR/MRP), member... 165 1e-39
gb|AAD37716.1|AF146074_1 (AF146074) ABC protein [Homo sapiens] 165 1e-39
sp|O15440|MRP5_HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 (... 165 1e-39
gi|11432255 ATP-binding cassette, sub-family C, member 5 [Homo s... 165 1e-39
sp|P45082|CYDD_HAEIN TRANSPORT ATP-BINDING PROTEIN CYDD >gi|1075... 165 1e-39
gb|AAC13734.1| (L20805) homology to the ATP dependent translocat... 164 2e-39
pir||JC5667 multidrug resistance protein, short type - human >gi... 164 2e-39
dbj|BAA76608.1| (AB019002) MRP5 [Homo sapiens] 164 2e-39
pir||S56036 probable transport protein cydD - Escherichia coli >... 164 2e-39
gb|AAA86667.1| (L36247) ATP-binding cassette protein [Fasciola h... 163 5e-39
gb|AAC36863.1| (L25859) cydD [Escherichia coli] >gi|739460|prf||... 161 2e-38
dbj|BAA96369.1| (AB035330) ABC protein [Physarum polycephalum] 160 4e-38
gb|AAA92852.1| (M90969) ATP-binding protein [Lactococcus lactis] 160 5e-38
pir||H72270 ABC transporter, ATP-binding protein - Thermotoga ma... 159 6e-38
emb|CAB61548.1| (AL133171) putative ABC transporter [Streptomyce... 158 2e-37
gi|11440169 ATP-binding cassette, sub-family B, member 9, isofor... 158 2e-37
dbj|BAA08631.1| (D49826) LipB [Serratia marcescens] 155 9e-37
pir||T34527 hypothetical protein DKFZp434I2115.1 - human (fragme... 147 3e-34
pir||E75277 ABC transporter, ATP-binding protein, MsbA family - ... 145 1e-33
pir||B82231 transport ATP-binding protein CydD VC1181 [imported]... 144 3e-33
pir||A49454 ABC transporter homolog YbjA - Escherichia coli 132 1e-29
gb|AAG15221.1|AF288462_1 (AF288462) AbcB [Chloroflexus aurantiacus] 115 1e-24
dbj|BAA96044.1| (AB040953) KIAA1520 protein [Homo sapiens] 113 4e-24
pir||S57561 strV protein - Streptomyces glaucescens >gi|2127536|... 111 2e-23
gi|11440164 ATP-binding cassette, sub-family B, member 9, isofor... 109 1e-22
pir||H70788 probable peptidetransport system ABC-transporter ATP... 92 2e-17
pir||A72618 probable oligopeptide transport ATP-binding protein ... 85 2e-15
sp|P44692|ZNUC_HAEIN HIGH-AFFINITY ZINC UPTAKE SYSTEM ATP-BINDIN... 85 3e-15
pir||C75593 probable ABC transporter, ATP-binding protein - Dein... 85 3e-15
gb|AAC71714.1| (AF061267) ATPase component HtxD [Pseudomonas stu... 83 1e-14
pir||A75083 ATP-binding transport protein PAB1668 - Pyrococcus a... 83 1e-14
gb|AAK42768.1| ABC transporter, ATP binding protein [Sulfolobus ... 81 4e-14
pir||S75652 ABC-type transport protein sll1878 - Synechocystis s... 81 4e-14
gb|AAB59057.1| (J01648) malK [Escherichia coli] 80 7e-14
dbj|BAA32782.1| (AB012090) SMRP/MRP5 [Mus musculus] 80 7e-14
pir||E72393 oligopeptide ABC transporter, ATP-binding protein - ... 78 2e-13
dbj|BAB04070.1| (AP001508) oligopeptide ABC transporter (ATP-bin... 78 2e-13
gi|11466697 mbpX [Marchantia polymorpha] >gi|126794|sp|P10091|CY... 78 3e-13
emb|CAA57304.1| (X81644) white [synthetic construct] >gi|870997|... 78 3e-13
pir||B64551 oligopeptide ABC transporter, ATP-binding protein - ... 78 3e-13
dbj|BAA78210.1| (AB028139) white protein [Drosophila melanogaster] 78 3e-13
pir||G72049 peptide ABC transporter, ATP-binding protein CP0064 ... 77 4e-13
pir||A70482 ABC transporter - Aquifex aeolicus >gi|2984331|gb|AA... 76 1e-12
pir||T50583 ABC-type transport protein, ATP-binding component [i... 76 1e-12
gb|AAF81232.1| (AF263012) ABC transporter ATP binding protein [S... 76 1e-12
pir||E71483 probable dipeptide transport - Chlamydia trachomatis... 75 2e-12
pir||E71957 ABC transporter, ATP-binding protein - Helicobacter ... 75 2e-12
sp|P37624|YHIH_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 75 2e-12
pir||S47705 hypothetical protein f648 - Escherichia coli >gi|912... 74 4e-12
pir||T35983 probable peptide transport ATP-binding protein - Str... 73 1e-11
pir||T44856 molybdenum transport ATPase (EC 3.6.1.-) [imported] ... 73 1e-11
dbj|BAB16596.1| (AB037937) ABC2 [Rattus norvegicus] 73 1e-11
sp|Q58429|YA23_METJA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR... 72 1e-11
gb|AAB48547.1| (U50749) unknown [Leuconostoc mesenteroides subsp... 72 2e-11
pir||A59189 ATP-binding cassette transporter - human (fragment) ... 71 3e-11
gb|AAG09372.1|AF178941_1 (AF178941) ATP-binding cassette sub-fam... 71 3e-11
pir||E71130 probable oligopeptide transport ATP-binding protein ... 71 4e-11
pir||H82355 peptide ABC transporter, ATP-binding protein VC0170 ... 71 4e-11
pir||T36437 probable ABC-type transport system ATP-binding prote... 70 7e-11
>pir||F75142 abc transporter ATP-binding protein PAB2148 - Pyrococcus abyssi
(strain Orsay) >gi|5457731|emb|CAB49221.1| (AJ248284)
ABC TRANSPORTER ATP-BINDING PROTEIN [Pyrococcus abyssi]
Length = 580
Score = 1121 bits (2868), Expect = 0.0
Identities = 580/580 (100%), Positives = 580/580 (100%)
Query: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE 60
MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE
Sbjct: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE 60
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD
Sbjct: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL
Sbjct: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR
Sbjct: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS
Sbjct: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
Query: 301 MYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNL 360
MYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNL
Sbjct: 301 MYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNL 360
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ
Sbjct: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE
Sbjct: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA
Sbjct: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
Query: 541 DKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
DKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG
Sbjct: 541 DKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
>pir||B71182 probable ABC transporter ATP-binding protein - Pyrococcus
horikoshii >gi|3258166|dbj|BAA30849.1| (AP000007) 582aa
long hypothetical ABC transporter ATP-binding protein
[Pyrococcus horikoshii]
Length = 582
Score = 997 bits (2549), Expect = 0.0
Identities = 497/576 (86%), Positives = 545/576 (94%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG 62
++SS SLL RFI+EALSE++TL +V++SIVGSA+ANLASPY+L +AID+YI+PG+Y EL
Sbjct: 7 NESSFSLLIRFIREALSEKKTLVVVIISIVGSAIANLASPYVLHIAIDNYIVPGKYGELW 66
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
F+ +LYLLSL+ QWFF TLQT+YTEVFGQ VL+ LRS+LHEKIL SNLDFFK KSTGDLV
Sbjct: 67 FVTLLYLLSLIGQWFFMTLQTYYTEVFGQGVLKRLRSKLHEKILISNLDFFKEKSTGDLV 126
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
SRIINDTN+VNDVLVSGLLGGLGS+LSLAGII+AM LLDVKLTLVTL SVPLMV++A YF
Sbjct: 127 SRIINDTNIVNDVLVSGLLGGLGSLLSLAGIIIAMFLLDVKLTLVTLASVPLMVLVAYYF 186
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKE+DVE+EFSKVS ETIKAYLRVA
Sbjct: 187 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKERDVEREFSKVSLETIKAYLRVA 246
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
+YMG+FWPLMNI SLLSVI VIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY
Sbjct: 247 VYMGVFWPLMNITSLLSVIAVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 306
Query: 303 DSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYI 362
DSLQSALAALERIYEILDDENVEDY GI+VE+L GEIEFRNVWFEYE+GRPVLKD+NL I
Sbjct: 307 DSLQSALAALERIYEILDDENVEDYNGINVERLNGEIEFRNVWFEYERGRPVLKDINLLI 366
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
P SKVAIVGKTGAGKTT+ANLIMRFYDPTKG+I YDGI+G+KISRKSLR+RIGYVPQET
Sbjct: 367 PSGSKVAIVGKTGAGKTTLANLIMRFYDPTKGDIFYDGIEGRKISRKSLRRRIGYVPQET 426
Query: 423 YLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
YLFPGTIMENILMANPEA+EEDVIRVCKELGIH+FIMKLP GY+TSAGEAGKLLS+GERQ
Sbjct: 427 YLFPGTIMENILMANPEAREEDVIRVCKELGIHEFIMKLPNGYKTSAGEAGKLLSLGERQ 486
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
LISLARA+LKDPDIVILDEALSSVDPKTEQLVQNAM+KLMEGRTSIIIAHRLSITRFADK
Sbjct: 487 LISLARALLKDPDIVILDEALSSVDPKTEQLVQNAMLKLMEGRTSIIIAHRLSITRFADK 546
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
VIVV DGRI+EEG P LL +KGYFY+LYTSQ+QEV
Sbjct: 547 VIVVKDGRIIEEGPPKLLLEKKGYFYRLYTSQVQEV 582
>sp|Q9WYC4|Y288_THEMA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN TM0288
>gi|7445855|pir||F72396 ABC transporter, ATP-binding
protein - Thermotoga maritima (strain MSB8)
>gi|4980786|gb|AAD35376.1|AE001710_11 (AE001710) ABC
transporter, ATP-binding protein [Thermotoga maritima]
Length = 598
Score = 442 bits (1124), Expect = e-123
Identities = 230/576 (39%), Positives = 364/576 (62%), Gaps = 9/576 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG- 62
K+ + L+R + TL +V V + S++ + SPY++ ID +P R+ L
Sbjct: 19 KNPTATLRRLLGYLRPHTFTLIMVFVFVTVSSILGVLSPYLIGKTIDVVFVPRRFDLLPR 78
Query: 63 ---FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTG 119
+ +Y L+ + W LQ Q V+ LR +L EK+ + + FF G
Sbjct: 79 YMLILGTIYALTSLLFW----LQGKIMLTLSQDVVFRLRKELFEKLQRVPVGFFDRTPHG 134
Query: 120 DLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIA 179
D++SR+IND + +N+VL + ++ I++LAG ++ M ++V L+LVTL+ VPL V+I
Sbjct: 135 DIISRVINDVDNINNVLGNSIIQFFSGIVTLAGAVIMMFRVNVILSLVTLSIVPLTVLIT 194
Query: 180 LYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYL 239
+ R+ + E ++ + +++ ++EE ++G+ I+ F +E+ ++F +V+ K
Sbjct: 195 QIVSSQTRKYFYENQRVLGQLNGIIEEDISGLTVIKLFTREEKEMEKFDRVNESLRKVGT 254
Query: 240 RVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
+ I+ G+ PLMN+ + L ++ +GG+LA K +++G + FI Y+++F P+N +
Sbjct: 255 KAQIFSGVLPPLMNMVNNLGFALISGFGGWLALKDIITVGTIATFIGYSRQFTRPLNELS 314
Query: 300 SMYDSLQSALAALERIYEILD-DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDV 358
+ ++ +Q ALA+ ERI+EILD +E +D + + + +++GEIEF+NVWF Y+K +PVLKD+
Sbjct: 315 NQFNMIQMALASAERIFEILDLEEEKDDPDAVELREVRGEIEFKNVWFSYDKKKPVLKDI 374
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+I P KVA+VG TG+GKTTI NL+MRFYD +G+IL DGID +KI R SLR IG V
Sbjct: 375 TFHIKPGQKVALVGPTGSGKTTIVNLLMRFYDVDRGQILVDGIDIRKIKRSSLRSSIGIV 434
Query: 419 PQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
Q+T LF T+ EN+ NP A +E++ K FI LP+GYET + G+ LS
Sbjct: 435 LQDTILFSTTVKENLKYGNPGATDEEIKEAAKLTHSDHFIKHLPEGYETVLTDNGEDLSQ 494
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQL+++ RA L +P I+ILDEA S+VD KTE+ +Q AM KLMEG+TSIIIAHRL+ +
Sbjct: 495 GQRQLLAITRAFLANPKILILDEATSNVDTKTEKSIQAAMWKLMEGKTSIIIAHRLNTIK 554
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
AD +IV+ DG IVE G EL+ ++G++Y+L+TSQ
Sbjct: 555 NADLIIVLRDGEIVEMGKHDELIQKRGFYYELFTSQ 590
>dbj|BAA96814.1| (AB040146) ABC transporter B [Thermus thermophilus]
Length = 600
Score = 411 bits (1046), Expect = e-114
Identities = 218/587 (37%), Positives = 366/587 (62%), Gaps = 17/587 (2%)
Query: 8 SLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPG-------RYKE 60
+L R ++ R + + ++ ++ LA A+P + AID ++P R+
Sbjct: 13 ALFARILRYVWPYRLQVVLALLFLLVVTLAAAATPLFFKWAIDLALVPTEPRPLAERFHL 72
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
L +I++ +L + T +T+ + GQ+VL +LRS L K+++ + F+ G
Sbjct: 73 LLWISLGFLAVRAVHFAATYGETYLIQWVGQRVLFDLRSDLFAKLMRLHPGFYDRNPVGR 132
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L++R+ +D + +N + GL+G + + +L G++ ML L KLTLV L P+++ +
Sbjct: 133 LMTRVTSDVDAINQFITGGLVGVIADLFTLVGLLGFMLFLSPKLTLVVLLVAPVLLAVTT 192
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+ MR AYRE R ++A++++ ++E+++G+ETI+ F KE++ E++F +++ + +A++
Sbjct: 193 WVRLGMRSAYREMRLRLARVNAALQENLSGVETIQLFVKEREREEKFDRLNRDLFRAWVE 252
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
+ + +F+P++ +V ++ YGG +GAVS+G++VAF+ Y ++ P+ ++
Sbjct: 253 IIRWFALFFPVVGFLGDFAVASLVYYGGGEVVRGAVSLGLLVAFVDYTRQLFQPLQDLSD 312
Query: 301 MYDSLQSALAALERIYEILD-DENVEDYEG-ISVEKLKGEIEFRNVWFEY-EKGRP---- 353
++ Q A+A+ ERI+ +LD +E ++D E + +GE+EFR+VW Y KG
Sbjct: 313 KFNLFQGAMASAERIFGVLDTEEELKDPEDPTPIRSFRGEVEFRDVWLAYTPKGVEPTEK 372
Query: 354 --VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
VLK V+ + P KVA+VG TGAGKT++ +LI RFYDP +G + DG+D ++ ++ L
Sbjct: 373 DWVLKGVSFRVRPGEKVALVGATGAGKTSVVSLIARFYDPQRGCVFLDGVDVRRYRQEEL 432
Query: 412 RKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
R+ +G V QE +LF GT+++N+ + +P E V V + LG H+FI++LPKGY+T GE
Sbjct: 433 RRHVGIVLQEPFLFSGTVLDNLRLFDPSVPPERVEEVSRFLGAHEFILRLPKGYQTVLGE 492
Query: 472 AGKLLSVGERQLISLARAMLKDPDI-VILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
G LS GE+QL++L RA+L PDI +ILDEA +SVD +TE+ +Q A+ K MEGRTS+II
Sbjct: 493 RGAGLSTGEKQLLALVRALLASPDILLILDEATASVDSETEKRLQEALYKAMEGRTSLII 552
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
AHRLS R D+++V GR+VEEGS ELL++ GY+ LY Q QE
Sbjct: 553 AHRLSTIRHVDRILVFRKGRLVEEGSHEELLAKGGYYAALYRLQFQE 599
>sp|P54719|YFIC_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN 2 IN GLVBC
3'REGION >gi|7445745|pir||F69802 ABC transporter
(ATP-binding protein) homolog yfiC - Bacillus subtilis
>gi|1486245|dbj|BAA09107.1| (D50543) unknown [Bacillus
subtilis] >gi|2633146|emb|CAB12651.1| (Z99108) similar
to ABC transporter (ATP-binding protein) [Bacillus
subtilis]
Length = 604
Score = 397 bits (1009), Expect = e-109
Identities = 209/573 (36%), Positives = 350/573 (60%), Gaps = 11/573 (1%)
Query: 12 RFIKEALSERRTLAIVVV-SIVGSALANLASPYILRVAIDHYII----PGRYKELGFIAM 66
R I L+ER+ L I+V+ +V SA+ L P+++ AIDH+I+ G L +
Sbjct: 36 RRIWSYLAERKGLLILVMLMVVISAIFGLLGPFVIGKAIDHFIVGKTVSGLIPVLLLLLA 95
Query: 67 LYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRII 126
+Y++ ++ WF Q ++ Q + +RS+L + + + FF + G+L+SR+
Sbjct: 96 IYIIQSLSLWF----QNYWMITISQGTVFRMRSELFTHLHELPIPFFDKQRHGELMSRVT 151
Query: 127 NDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKM 186
ND V+ L + ++ L S+++ G I ML + LTL+TLT +P+M + +
Sbjct: 152 NDIENVSSTLNTSVIQILSSVITFVGTIAVMLYMSPLLTLITLTIIPVMAASLKWITNRT 211
Query: 187 RRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG 246
+ ++E ++ + ++ +EESV+G + I+A+ +EK + EF + + + G
Sbjct: 212 GKLFKEQQKNLGDLNGYIEESVSGAKVIKAYSREKQITAEFLEKNAALKTSGFWAQTISG 271
Query: 247 IFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQ 306
+MN + LS ++ A GG A KG +SIG +V F +Y+++F P+N++ + ++++
Sbjct: 272 FIPKVMNSLNNLSFTMIAAIGGLFALKGWISIGSIVVFAEYSRQFTRPLNDLANQFNTML 331
Query: 307 SALAALERIYEILDDENVEDYEGISVEK--LKGEIEFRNVWFEYEKGRPVLKDVNLYIPP 364
SA+A ER++++LD++ + E +V + G IEFR+V F Y+KG+ LK + +P
Sbjct: 332 SAIAGAERVFDVLDEKEEREDEKNAVHQPIQTGSIEFRDVSFGYDKGQQTLKHLQFTVPA 391
Query: 365 ASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYL 424
+A VG TGAGKTT+ NL+ RFY+P G+IL DG D K ++R SLRK +G+V Q+++L
Sbjct: 392 GQSIAFVGPTGAGKTTVTNLLARFYEPNDGKILIDGTDIKTLTRASLRKNMGFVLQDSFL 451
Query: 425 FPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLI 484
F GTI ENI +A +++V K H FI +LPKGY+T + G +S G++QLI
Sbjct: 452 FQGTIRENIRYGRLDASDQEVEAAAKTANAHSFIERLPKGYDTVLTQNGSGISQGQKQLI 511
Query: 485 SLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVI 544
S+ARA+L DP ++ILDEA S++D TE +Q A+ +LMEGRTS+IIAHRL+ + AD+++
Sbjct: 512 SIARAVLADPVLLILDEATSNIDTVTEVNIQEALARLMEGRTSVIIAHRLNTIQRADQIV 571
Query: 545 VVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
V+ +G ++E+GS EL+ +KG++ LY SQ ++
Sbjct: 572 VLKNGEMIEKGSHDELIRQKGFYSDLYESQFEK 604
>pir||S72638 hypothetical ABC exporter component B - Thermoanaerobacterium
thermosulfurigenes >gi|1542975|gb|AAB08042.1| (U50951)
AbcB [Thermoanaerobacterium thermosulfurigenes]
Length = 594
Score = 372 bits (946), Expect = e-102
Identities = 201/573 (35%), Positives = 333/573 (58%), Gaps = 5/573 (0%)
Query: 5 SSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFI 64
S+ +LKR + + +V++ ++ +L +P +++ AID I G L I
Sbjct: 16 SNFVILKRLFSYLGKYKLKVFVVIMFLIFEMAVSLVNPVLMKTAIDKNIRNGDINGLFVI 75
Query: 65 AMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSR 124
+L + + + +L N+R +L+ I + + FF ++ G +++R
Sbjct: 76 GILMVSLNFLSMMASRTRIVKMASVTNDILLNIRHELYSHIQKLSFSFFDSRPVGKILAR 135
Query: 125 IINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGG 184
+I D N + D+ + + + IL++ + M L+ KL L ++ +P++VI
Sbjct: 136 VIGDVNSLQDLFNNSVTNFIPQILTVICVGTMMFYLNSKLALASMILLPMLVIGLFSIET 195
Query: 185 KMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIY 244
RR ++E R+K + ++ E +GI+ ++ F E F K+ + + ++++
Sbjct: 196 LSRRRWQEFRRKRSTFNAYTHEDFSGIKVVQEFANEDKTSSVFFKLVKDMMDSFIKAVRL 255
Query: 245 MGIFWPLMNIASLLSVIVVIAYGG-YLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
+FWP+++ + + +++ + ++ Y V+IG ++AF Y F PI ++ + Y+
Sbjct: 256 NDLFWPMVDASYGIGAVILYYFSAKFMGY--GVTIGTIIAFTMYIGMFWRPILDISNFYN 313
Query: 304 SLQSALAALERIYEILDDEN--VEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLY 361
SL + A+ ERI+EI+D E V+ I + K+KG +EF+NV F YE G VL DV+
Sbjct: 314 SLVMSFASAERIFEIMDIEPDIVDMKNAIKMPKIKGNVEFKNVTFGYEDGSVVLDDVSFK 373
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
+ +A+VG TGAGKTTI NLI RFYDP+KG +L DG D K + +SLR ++G + Q+
Sbjct: 374 VNAGETIALVGPTGAGKTTIVNLISRFYDPSKGAVLIDGKDIKHVELESLRSQMGIMLQD 433
Query: 422 TYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
T+LF TI ENI +A +E++I K + H+FIMK+ KGY+T E G LSVG+R
Sbjct: 434 TFLFSATIKENIRYGKLDATDEEIIAAAKAVNAHEFIMKMEKGYDTEVNERGSRLSVGQR 493
Query: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFAD 541
QLIS ARA+L +P I+ILDEA S++D +TE+LVQ + +L+ GRTS +IAHRLS R AD
Sbjct: 494 QLISFARALLANPRILILDEATSNIDTQTERLVQKGIQRLLSGRTSFVIAHRLSTIRDAD 553
Query: 542 KVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+++V+D G+IVE G+ EL++ +G +Y LY SQ
Sbjct: 554 RIMVIDGGKIVETGTHDELMNLRGLYYDLYMSQ 586
>pir||A69858 ABC transporter (ATP-binding protein) homolog yknV - Bacillus
subtilis >gi|2633804|emb|CAB13306.1| (Z99111) similar to
ABC transporter (ATP-binding protein) [Bacillus
subtilis] >gi|3282117|gb|AAC24907.1| (AF012285) YknV
[Bacillus subtilis]
Length = 604
Score = 369 bits (938), Expect = e-101
Identities = 209/548 (38%), Positives = 330/548 (60%), Gaps = 6/548 (1%)
Query: 31 IVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS--LVAQWFFTTLQTFYTEV 88
++G+A+ L P ++ V + I GR EL I +++++S V + L+ +
Sbjct: 53 LIGTAV-KLVIPILIGVYVLDQAITGRNSEL-LIQLIFIISGLYVLNYAANVLRIRWMNQ 110
Query: 89 FGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSIL 148
GQ V+ +LR L + + + FF +S G ++ RI+ND N + ++ SG++ L +L
Sbjct: 111 LGQHVIYDLRQHLFTHVQRLSHRFFDQRSAGSILVRIMNDINSLQELFTSGVINLLTDLL 170
Query: 149 SLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESV 208
LAG+I+ + L +LT+ + ++P+M I+ K+RR+++ R K +K++S + ES+
Sbjct: 171 LLAGVIIILFTLSPELTIAIMVTLPIMFFISTSLRKKIRRSWQTVRLKQSKLNSHLNESI 230
Query: 209 AGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGG 268
GI +AF +E++ F V+ E +++ +F PL+ + + + V+I YG
Sbjct: 231 QGIRVTQAFTQEEENMAYFDGVNQENYESWREATRKNAMFRPLVEMTNAIGTAVLIWYGA 290
Query: 269 YLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE-NVEDY 327
L ++IGV V+F Y F PI+ + +Y+ L +A+ ERI+E LD++ NV++
Sbjct: 291 TLIMNETITIGVFVSFAFYLGMFWEPISRLGQVYNQLLMGMASSERIFEFLDEQPNVKEK 350
Query: 328 -EGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIM 386
I EK+ GEI F V F Y++ R L V+ IP S +A+VG TG+GKTTIANLI
Sbjct: 351 PNAIHNEKINGEISFEEVEFSYDEKRKALHAVSFSIPAGSTLALVGHTGSGKTTIANLIS 410
Query: 387 RFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVI 446
RFYD G I DGI K +S SLR +I V Q+T++F GTIMENI P A +E+V+
Sbjct: 411 RFYDAAGGTIKIDGIPIKDLSLASLRSQISIVLQDTFIFSGTIMENIRFGRPNASDEEVM 470
Query: 447 RVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSV 506
+ + +G +FI L +GY T E G +LS G+RQLIS ARA+L DP I+ILDEA +S+
Sbjct: 471 KASQAVGADEFISDLAEGYATEVEERGSVLSAGQRQLISFARALLADPAIIILDEATASI 530
Query: 507 DPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGY 566
D +TE +Q A+ L++GRT+++IAHRLS R AD++IV+D GR +EEG+ +LL++ G
Sbjct: 531 DTETEVKIQQALKTLLKGRTAVMIAHRLSTIRDADRIIVLDHGRKIEEGNHDQLLAKGGI 590
Query: 567 FYKLYTSQ 574
+ L +Q
Sbjct: 591 YAGLVKAQ 598
>dbj|BAB04845.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 601
Score = 369 bits (937), Expect = e-101
Identities = 207/571 (36%), Positives = 334/571 (58%), Gaps = 16/571 (2%)
Query: 17 ALSERRTLAIVVVSIVGSALANLASPYILRV-AIDHYIIPG----RYKELGFIAMLYLLS 71
+L + +A+++V+ V L P I+ V AIDH I G Y+ + LY +S
Sbjct: 40 SLLPKTVVAMLIVTAV-----RLFVPIIIGVLAIDHAIAAGDLNVMYQLAALVLGLYSIS 94
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
VA F + + GQ V+ ++R+ L I + + FF +S G ++ R++ND N
Sbjct: 95 YVANVF----RIRWMNEIGQHVIYDIRADLFNHIQRLSHRFFDQRSAGSILVRVVNDVNS 150
Query: 132 VNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
+ D+ +G++ L I+ L GIIV + L +L ++ L +P+M I+ +RR+++
Sbjct: 151 LQDLFTNGVINLLMDIVILLGIIVILFSLSPELAILILIVLPIMFFISTKLRRNIRRSWQ 210
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
R + +K++S + ES+ GI +AF +EK+ + F ++ E +++ +F P
Sbjct: 211 TVRLRQSKLNSHLNESIQGIRVTQAFSQEKENMRFFRDINEENFQSWKDATRMNALFRPF 270
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ +AS + +V+I YG L +++GV V+F Y F PI+ + +Y+ L +A+
Sbjct: 271 VEMASAIGAVVLIWYGVSLIQSEVLTVGVFVSFAFYLGMFWEPISRLGQVYNQLLVGMAS 330
Query: 312 LERIYEILDDENV--EDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVA 369
ERI+E LD++ E +++ +++G + F V F Y+ R L D++ I +A
Sbjct: 331 SERIFEFLDEKPSVPEKENAVTLHEMRGHVTFEQVEFSYDDKRKALNDISFEIKAGQTIA 390
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
+VG TG+GK+TI NLI RFYDPT G I DG+D + I SLR + +V Q+T++F GTI
Sbjct: 391 LVGHTGSGKSTIVNLISRFYDPTAGVIKIDGVDLRDIQLNSLRTNVSFVLQDTFIFAGTI 450
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
MENI P A +E+V + +G +DFI +LP GY+T E G +LSVGERQL+S ARA
Sbjct: 451 MENIRFGRPTATDEEVKAAAEAIGANDFIERLPNGYDTEVEEKGNVLSVGERQLLSFARA 510
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
+L DP I+ILDEA +S+D +TE +Q + KL+ RT+I+IAHRLS R AD++IV++ G
Sbjct: 511 LLADPKILILDEATASIDTETELKIQAGLKKLLHDRTAIMIAHRLSTIRDADQIIVLEQG 570
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
I+E+G+ EL+ +G +Y L +Q + G
Sbjct: 571 DIIEQGTHSELMDARGTYYGLVKAQYEASAG 601
>dbj|BAB04534.1| (AP001509) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 611
Score = 367 bits (931), Expect = e-100
Identities = 197/563 (34%), Positives = 338/563 (59%), Gaps = 4/563 (0%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L+R ++ R L +V ++++ S++ L P+++ +AIDHY++ G L F M+ L
Sbjct: 36 LRRIWTYLVNYRGRLLLVFLAVLLSSVLGLLGPFVIGMAIDHYLVEGDTSSL-FKVMIGL 94
Query: 70 LSLVAQWFFTT-LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
L++ A + + LQ + Q+ + ++RS L + + FF K G+L+SR+ ND
Sbjct: 95 LAIYAVYSLSMWLQQVWMIGIAQQTVYSIRSDLFHHFHRLPIPFFDKKQHGELMSRMTND 154
Query: 129 TNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRR 188
+++ L S ++ S+L+L GI++ ML L +T++T+T VPLMV + +
Sbjct: 155 IENISNTLNSSVIKIFSSVLTLVGIMIVMLWLSPLMTVITMTVVPLMVFGLKWITRRTAV 214
Query: 189 AYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIF 248
+++ ++ + ++ +EE+V+G I+AF +E FS+ + E Y G
Sbjct: 215 FFKQQQKALGDLNGYIEETVSGQSVIQAFSREGAAIATFSEKNRELKTTSFWAQTYTGFI 274
Query: 249 WPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSA 308
+MN+ + L+ V+ GG LA +G+++IG++V F +YA++F P+N++ + ++ L +A
Sbjct: 275 PKVMNVLNSLNFAVIAGVGGILAMRGSITIGIIVIFAEYARQFTRPLNDLANQFNMLLAA 334
Query: 309 LAALERIYEILDDENVEDYEGIS-VEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASK 367
+A ER+++ILD++ ++ V+ +KGE+ F V F YE+ + L +++ ++ P
Sbjct: 335 IAGAERVFDILDEQEERHHDQTKQVKSIKGEVSFEQVSFSYEQ-KTTLNNLSFHVNPGET 393
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
VA++G TGAGKTTI L+ RFY+ G I DG D R+S R+ + +V QE++LF G
Sbjct: 394 VALIGPTGAGKTTIIRLLSRFYEWDGGAIYVDGEDVTTWDRESYRRHLAFVLQESFLFQG 453
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
TI ENI EA +E+V K H FIM+LP Y+T G +S G++QL+S+A
Sbjct: 454 TIRENIRYGRLEATDEEVEAAAKMANAHSFIMRLPDQYDTVLDSDGSGISQGQKQLLSIA 513
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
RAM+ +P I+ILDEA S++D TE +Q A+ +LM GRTS +IAHRL+ + AD ++V++
Sbjct: 514 RAMIANPSILILDEATSNIDTITELNIQEALHRLMNGRTSFVIAHRLNTIQHADVILVLE 573
Query: 548 DGRIVEEGSPGELLSRKGYFYKL 570
G +VE+GS EL+++KG +Y +
Sbjct: 574 KGTLVEQGSHEELMAKKGVYYDM 596
>gb|AAK43114.1| ABC transporter, ATP binding protein [Sulfolobus solfataricus]
Length = 863
Score = 361 bits (917), Expect = 1e-98
Identities = 200/578 (34%), Positives = 334/578 (57%), Gaps = 5/578 (0%)
Query: 4 KSSLSLLKRFIKEALSERRTLAI-VVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG 62
K +S L+ A R+T+ + +S++ + L NL PY+L++ ID ++ +
Sbjct: 114 KVGVSTLRWLWTIASRYRKTMIVGATLSLITTGL-NLVPPYLLKILIDSVLLSPSHPSTL 172
Query: 63 FI-AMLYLL-SLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
FI ++YL+ S A +++Q G +++ +LR L++ + + F + S
Sbjct: 173 FINIIIYLIVSYSALALLSSIQNRILNNLGSRIINDLREILYKHAINHDYSFIERISPSR 232
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
++SR+ D N +LV GL + ++ ++ GI V + L+ L L VP ++ + +
Sbjct: 233 ILSRLTTDAGNTNWLLVWGLPTLVTNLFTIIGIGVILFTLNPTLAAFILIPVPAIIYLII 292
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+ K R Y ++ A I+S + +++ +R+F KE+ K ++ + ++ +
Sbjct: 293 SYRRKSHRLYHRNWRRSADITSRINDTIPNFLVVRSFSKEEYESKRLREMLNKLYESSVA 352
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
+ ++WPLM LS +++ GG+ G + IGV+ AFI Y +F GPINN+ +
Sbjct: 353 INKMNSVYWPLMGFIVNLSTVLIWWVGGHEVISGIIEIGVITAFIAYVSQFYGPINNLSN 412
Query: 301 MYDSLQSALAALERIYEILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVN 359
+ +Q +L + ERI E+L+ + + + E + EI F +V+F Y+ PV+KD+N
Sbjct: 413 VLPFIQQSLTSAERIREVLEAKPQITNPENPKRPNMPAEIRFEHVYFGYDPHFPVIKDIN 472
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
+ I P KVAIVGK+G+GK+TIA L++RFYD +G IL DGID ++I LR+++ YVP
Sbjct: 473 IGIKPGEKVAIVGKSGSGKSTIAKLLLRFYDVNEGRILIDGIDIREIDLNYLRRKVAYVP 532
Query: 420 QETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
Q+ LF T+ N+ E D+IR CK IHD I+KLP Y+T GE G LS G
Sbjct: 533 QDVVLFDTTVGYNVAYGTDNVSEIDIIRACKIAKIHDEIVKLPFAYDTILGERGTYLSGG 592
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
+RQ +S+ARA++K+PD++I DEA S++D +E+ V MI + +G+T I+I H +
Sbjct: 593 QRQRLSIARAIIKNPDVLIFDEATSNLDVTSEREVYETMIDVSKGKTVIMITHNVHEVMN 652
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
+DKVIV+ +G++VEEG P ELL++KG FYK++ Q+ E
Sbjct: 653 SDKVIVLSNGKVVEEGKPIELLNKKGEFYKMFKEQINE 690
>pir||G69815 ABC transporter (ATP-binding protein) homolog ygaD - Bacillus
subtilis >gi|1673392|emb|CAB04797.1| (Z82044)
unidentified transporter-ATP binding [Bacillus subtilis]
>gi|2633192|emb|CAB12697.1| (Z99108) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 589
Score = 361 bits (917), Expect = 1e-98
Identities = 192/580 (33%), Positives = 342/580 (58%), Gaps = 9/580 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE--- 60
+S++ ++KR+++ ++ + + V+ + LA P +L+ +D I G
Sbjct: 7 ESTVGVMKRYMQFVKPYKKQIFVTVLIGIVKFSIPLALPLLLKYVVDDIIQGGGTASDKT 66
Query: 61 ---LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS 117
+A+++ L L+ + + ++ + KVL ++R++L + I + +L F+
Sbjct: 67 TSLFTIMAIMFALFLILRPPVEYYRQYFAQWTASKVLYDIRAKLFDHIQKLSLRFYANTR 126
Query: 118 TGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
TG+++SR+IND D +++GL+ +L++ +I ML LDVKLTL+++ PL I
Sbjct: 127 TGEVISRVINDVEQTKDFVITGLMNIWLDMLTILIVISIMLTLDVKLTLISIVLFPLYGI 186
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
YF G++R+ RE Q +A++ + E + G+ IR+F E + +F++ + +
Sbjct: 187 SVKYFYGRLRKLTRERSQALAQVQGHLHERIQGMPVIRSFAIEDHEQAQFNEKNGHFLDK 246
Query: 238 YLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINN 297
+R + + ++N + L+ ++VIA GY G +++G +VAF+ Y R P+
Sbjct: 247 AIRHTNWNAKTFAVVNTITDLAPLIVIACAGYFVINGPLTVGTMVAFVGYIDRMYNPVRR 306
Query: 298 VVSMYDSLQSALAALERIYEILDD--ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP-V 354
+++ +L ++A+++R++E +D+ E + I ++++G +EF+NV F+YEK + +
Sbjct: 307 LINSSTTLTQSIASMDRVFEFIDEPYELTDKPNAIKADQIRGGVEFQNVSFQYEKDKENI 366
Query: 355 LKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKR 414
L DV+L + VA+VG +G GK+T+ +LI RFYD T G +L DG D + +SLR +
Sbjct: 367 LHDVSLKVNRGETVALVGMSGGGKSTLVSLIPRFYDVTSGRLLIDGTDIRDYEARSLRNQ 426
Query: 415 IGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGK 474
+G V Q+T+LF TI ENI + P+A E++I K H+FIM P+GYET GE G
Sbjct: 427 VGMVLQDTFLFSETIRENIAIGKPDATLEEIIEAAKAANAHEFIMSFPEGYETRVGERGV 486
Query: 475 LLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRL 534
LS G++Q IS+AR LK+P ++ILDEA S++D ++E +Q AM KL + RT+ ++AHRL
Sbjct: 487 KLSGGQKQRISIARVFLKNPPLLILDEATSALDLESEHYIQEAMDKLAKDRTTFVVAHRL 546
Query: 535 SITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
S ADK++V+++G I+E G+ EL+ + + L+T Q
Sbjct: 547 STITHADKIVVMENGTIIEIGTHDELMDYESQYKHLFTIQ 586
>pir||G75321 ABC transporter, ATP-binding protein, MsbA family - Deinococcus
radiodurans (strain R1)
>gi|6459844|gb|AAF11602.1|AE002041_6 (AE002041) ABC
transporter, ATP-binding protein, MsbA family
[Deinococcus radiodurans]
Length = 619
Score = 360 bits (915), Expect = 2e-98
Identities = 195/599 (32%), Positives = 345/599 (57%), Gaps = 35/599 (5%)
Query: 10 LKRFIKEALSERRTLAI--VVVSIVGSALANLASPYILRVAIDHYIIP----------GR 57
L R I L +TLA V+++++ +AL L + + R AIDHY++P
Sbjct: 16 LTRRIIGYLGPYKTLAAAGVLLALLTAALQPLPT-LLQRYAIDHYLVPYTNGSNTDAAAL 74
Query: 58 YKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS 117
Y+ L + + Y+ V ++ T L T GQ VLR++R+ + K+ + +L +F
Sbjct: 75 YQGLTMVVLGYVALRVLEFVLTYLSTITVGYLGQNVLRDIRADVFGKLQRLHLRYFDQNP 134
Query: 118 TGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
G L++R+ +D + +N + GL+ + S + + ML ++ +L L+ T +P++
Sbjct: 135 VGRLITRVTSDVDAINQFITGGLISMMTSTFLIIVFMTVMLTINWRLALIAFTVLPVLFY 194
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
+F GK+R A+RETR + A ++S + E++ G+ T++ FG+E+ +F + + +
Sbjct: 195 ATNFFRGKLREAFRETRTQQAIVNSKLNENITGMLTVQLFGRERRSALDFDHSNRALLTS 254
Query: 238 YLRVAIYMGIFWPLMNIASLLSVIVVIAYGGY---------LAYKGAVSIGVVVAFIQYA 288
+ +F P + + +++ +V+ + A+S+G + AF+Q+
Sbjct: 255 LENSVKWFSLFMPTVAVLGQVAIALVLYFAARQILGVDVVGTGTAAAISVGTLFAFVQWT 314
Query: 289 QRFRGPINNVVSMYDSLQSALAALERIYEILDDEN--VEDYEGISVEKLKGEIEFRNVWF 346
Q+ PI ++ ++++LQ+A A+ ERI+ +LD E + + ++ +G+++F VWF
Sbjct: 315 QQLFQPIQDLADVFNNLQAATASSERIFGVLDTEEEITDKPDAKTLVNFRGQVDFDRVWF 374
Query: 347 EY----------EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEI 396
Y E R +L+D +L+I P VA+VG TGAGKT++ L+ RFYD +G +
Sbjct: 375 AYSEDVTAQTPDEDDRWILRDFDLHIQPGESVALVGATGAGKTSVTALVSRFYDVQRGAV 434
Query: 397 LYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHD 456
DG D + + + LR+ +G V Q+ +LF GTI N+ + NP + V+ C+ +G+HD
Sbjct: 435 RVDGTDVRDLQQHDLRRHVGVVLQDVFLFAGTIESNLTLDNPAIPHDRVVEACQYVGVHD 494
Query: 457 FIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDI-VILDEALSSVDPKTEQLVQ 515
+I+ L GY+T E G LS G++QL++ ARA++++PDI ++LDEA ++VD +TE +Q
Sbjct: 495 YILSLENGYQTEVRERGATLSTGQKQLLAFARALIQNPDILLVLDEATANVDTETELRIQ 554
Query: 516 NAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+A+ K+M+GRTSIIIAHRLS D++IV+ GRIVE+G+ +L+++ GY+ KL Q
Sbjct: 555 DALKKVMQGRTSIIIAHRLSTIEHCDRIIVMRRGRIVEQGTHAQLIAQGGYYAKLNALQ 613
>emb|CAB69752.1| (AL137187) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 642
Score = 350 bits (888), Expect = 3e-95
Identities = 194/530 (36%), Positives = 309/530 (57%), Gaps = 6/530 (1%)
Query: 54 IPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRN---LRSQLHEKILQSNL 110
+PG+ + G + + LL+L L T + + V R LR + K+ + L
Sbjct: 107 VPGQGIDFGAVGEVLLLALATFAVAGLLMAVATRLVNRAVNRTMFRLREDVQTKLSRLPL 166
Query: 111 DFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLT 170
+F + G+++SR ND + + L + + S+L++ G++ M + L LV L
Sbjct: 167 SYFDKRQRGEVLSRATNDIDNIGQTLQQSMGQLINSLLTIIGVLAMMFYVSWILALVALV 226
Query: 171 SVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKV 230
+VPL ++A G + + + + + ++++ +EE G ++ FG++++ K+F++
Sbjct: 227 TVPLSFVVATRVGKRSQPQFVQQWRSTGQLNAHIEEMYTGHALVKVFGRQEESAKQFAEQ 286
Query: 231 STETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQR 290
+ +A + GI PLM S L+ ++V GG G +SIG V AFIQY+++
Sbjct: 287 NDALYEAGFKAQFNSGIMQPLMMCVSNLNYVLVAVVGGLRVASGQLSIGDVQAFIQYSRQ 346
Query: 291 FRGPINNVVSMYDSLQSALAALERIYEILD--DENVEDYEGISVEKLKGEIEFRNVWFEY 348
F P+ V SM + +QS +A+ ER++E+LD +++ + G E L+G +E +V F Y
Sbjct: 347 FSMPLTQVASMANLVQSGVASAERVFELLDAEEQSADPIPGARPEDLRGRVELEHVSFRY 406
Query: 349 EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISR 408
+ +P+++D++L + P VAIVG TGAGKTT+ NL+MRFY+ + G I DG+D K+SR
Sbjct: 407 DPEKPLIEDLSLKVEPGHTVAIVGPTGAGKTTLVNLLMRFYEVSGGRITLDGVDIAKMSR 466
Query: 409 KSLRKRIGYVPQETYLFPGTIMENILM-ANPEAKEEDVIRVCKELGIHDFIMKLPKGYET 467
LR IG V Q+T+LF GTI ENI A+ E ++ + F+ LP GY+T
Sbjct: 467 DELRAGIGMVLQDTWLFGGTIAENIAYGASREVTRGEIEEAARAAHADRFVRTLPDGYDT 526
Query: 468 SAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTS 527
+ G +S GE+QLI++ARA L DP I++LDEA SSVD +TE L+Q AM KL GRTS
Sbjct: 527 VIDDEGTGVSAGEKQLITIARAFLSDPVILVLDEATSSVDTRTEVLIQKAMAKLAHGRTS 586
Query: 528 IIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
+IAHRLS R AD ++V++DG IVE+G+ ELL+ G + +LY +Q E
Sbjct: 587 FVIAHRLSTIRDADTILVMEDGAIVEQGAHTELLTADGAYARLYKAQFAE 636
>pir||C71182 probable ABC transporter ATP-binding protein - Pyrococcus
horikoshii >gi|3258167|dbj|BAA30850.1| (AP000007) 580aa
long hypothetical ABC transporter ATP-binding protein
[Pyrococcus horikoshii]
Length = 580
Score = 346 bits (878), Expect = 4e-94
Identities = 185/531 (34%), Positives = 312/531 (57%), Gaps = 2/531 (0%)
Query: 42 PYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQL 101
P ++R AID I+ +Y +L LL V F+ + Q + +R
Sbjct: 40 PVLIRNAIDKGIVTKKYSVAFNYGLLILLVAVFNGIFSFTGRYLLVKSAQHAVYYIRMDA 99
Query: 102 HEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLD 161
+ I + ++FF +G L+SRI NDT + L + + SI +A + M+ ++
Sbjct: 100 FKAIQRHRMEFFDKTFSGQLISRITNDTERITRFLSFRIRMFVYSIFLIAVSLYYMIRMN 159
Query: 162 VKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEK 221
V L+LV L ++ ++V++ + K+R Y + R + I+S+ ++AGI+TI++ E+
Sbjct: 160 VFLSLVALGTIAVVVLLNTTYATKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEE 219
Query: 222 DVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVV 281
+++++FSK + + ++ + L++ ++ YGG +++G +
Sbjct: 220 NIQEKFSKENENLYSLNIDAIKITALYGNAPFLILGLAMSAMLYYGGKAIIAKTLTVGEL 279
Query: 282 VAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD--ENVEDYEGISVEKLKGEI 339
VAF+ Y P+ + +Q +LAA R++E++D + ++ + + + KGE+
Sbjct: 280 VAFLTYMLTMMWPLRALGFTIGDIQRSLAAAARLFEVIDSAPKAIDAPDAVEINDPKGEV 339
Query: 340 EFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYD 399
EFR+VW Y GR VL+ VNL + P KV IVG G+GK++I LI RFY P KGE+L D
Sbjct: 340 EFRDVWLTYHTGRTVLRGVNLKVSPGEKVLIVGPPGSGKSSILKLIARFYVPDKGEVLID 399
Query: 400 GIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIM 459
G++ KKI +SLR+ + YVPQE ++F +I ENI +A P+AK +++IR K IHDFI
Sbjct: 400 GVNVKKIKTESLRRIVAYVPQEPFIFNRSIRENIALAKPDAKMDEIIRAAKIAKIHDFIS 459
Query: 460 KLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMI 519
LP GY+T GE G LS G+RQ I+LARA+L DP I++LD+ +S++D +TE+ + +
Sbjct: 460 SLPNGYDTIVGEKGVTLSGGQRQRIALARALLLDPKIILLDDPVSNLDAETEKRLVEDLK 519
Query: 520 KLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
++++GRT++I++ RLS+ + D+VIV+ DGRI+EEG P EL+ + G F ++
Sbjct: 520 EILKGRTALIVSQRLSLVKLTDRVIVIKDGRIIEEGKPSELVKKGGAFSEM 570
>sp|Q11047|YC72_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN RV1272C
>gi|7445796|pir||H70754 probable abc transporter -
Mycobacterium tuberculosis (strain H37RV)
>gi|1480314|emb|CAB00908.1| (Z77137) hypothetical
protein Rv1272c [Mycobacterium tuberculosis]
Length = 631
Score = 344 bits (872), Expect = 2e-93
Identities = 183/512 (35%), Positives = 294/512 (56%), Gaps = 4/512 (0%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKST 118
+ L LYL + + W Q + QK + LR+ + +K+ + L +F +
Sbjct: 121 RTLALALALYLAAALMIW----AQARLLNLTVQKTMVRLRTDVEDKVHRLPLSYFDGQQR 176
Query: 119 GDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVII 178
G+L+SR+ ND + + L + + SIL++ ++ M+ + L L+TL +VPL +++
Sbjct: 177 GELLSRVTNDIDNLQSSLSMTISQLVTSILTMVAVLAMMVSISGLLALITLLTVPLSLLV 236
Query: 179 ALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAY 238
+ + + ++++ +EE+ +G ++ FG + + F +++ + +A
Sbjct: 237 TRAITRRSQPLFVAHWTSTGRLNAHLEETYSGFTVVKTFGHQAAARERFHELNDDVYQAG 296
Query: 239 LRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNV 298
G+ P L + V GG G +++G + AFIQY ++F P++ +
Sbjct: 297 FGAQFLSGLVQPATAFIGNLGYVAVAVAGGLQVATGQITLGSIQAFIQYIRQFNMPLSQL 356
Query: 299 VSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDV 358
MY++LQS +A+ ER++++LD+ + L G +EF +V F Y G PV++D+
Sbjct: 357 AGMYNALQSGVASAERVFDVLDEPEESPEPEPELPNLTGRVEFEHVNFAYLPGTPVIRDL 416
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+L P S VAIVG TGAGKTT+ NL+MRFY+ G IL DG+D +SR+SLR RIG V
Sbjct: 417 SLVAEPGSTVAIVGPTGAGKTTLVNLLMRFYEIGSGRILIDGVDIASVSRQSLRSRIGMV 476
Query: 419 PQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
Q+T+L+ GTI ENI PEA ++++ + + F+ LP GY+T G +SV
Sbjct: 477 LQDTWLYDGTIAENIAYGRPEATTDEIVEAARAAHVDRFVNTLPAGYQTRVSGDGGSISV 536
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
GE+QLI++ARA L P ++ILDEA SSVD +TE L+Q AM +L RTS IIAHRLS R
Sbjct: 537 GEKQLITIARAFLARPQLLILDEATSSVDTRTELLIQRAMRELRRDRTSFIIAHRLSTIR 596
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
AD ++VV G+IVE G+ ELL+R+G +Y++
Sbjct: 597 DADHILVVQTGQIVERGNHAELLARRGVYYQM 628
>dbj|BAB04844.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 581
Score = 339 bits (860), Expect = 5e-92
Identities = 184/544 (33%), Positives = 313/544 (56%), Gaps = 2/544 (0%)
Query: 36 LANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLR 95
L + P IL+ ID+ +I GRY + ++A+ ++ + + + + ++FG +
Sbjct: 30 LMTVLYPIILQFTIDNAVIGGRYDLIPWLALALIIVMGFKGVMVYIHQYLGDLFGVTAVY 89
Query: 96 NLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIV 155
LR+ L+EK+ ++ TGDL+SR+ D L G + IL ++ +
Sbjct: 90 RLRNSLYEKLQYLPFRYYDNAKTGDLMSRLTGDVETFRFFLSFGFAQFIQFILLVSFSMG 149
Query: 156 AMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIR 215
ML V LTL T+ ++P + I+ F ++ +R+ R+ +AK+++ V+E+V+G+ T++
Sbjct: 150 VMLYYSVPLTLATMCTLPFLAIVVAKFDRRVHPGFRDIRKSLAKLNTKVQENVSGMNTVK 209
Query: 216 AFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGA 275
A +E + F + + + +L +A G ++PLM LS + ++++GGYL G+
Sbjct: 210 ALSQEDEEVSRFEDRNVDYRQKHLDIARVWGNYFPLMEFIGNLSAVFLLSFGGYLVITGS 269
Query: 276 VSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKL 335
+ G +VAF GPI N+ + ++ + A+ ER+ EILD+EN D L
Sbjct: 270 MQTGQLVAFFSLVWYIIGPIMNLGFIINTFSQSKASGERLLEILDEENRVDEGKDERTSL 329
Query: 336 KGEIEFRNVWFEYEKGR-PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKG 394
+G + FR+V Y P L++V+ P + +VG TG+GKT+I L+ RFY+ T G
Sbjct: 330 QGSVTFRDVCLNYRGAETPALQNVSFEAPAGKTIGLVGATGSGKTSIVQLVNRFYERTSG 389
Query: 395 EILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGI 454
EIL DG + ++LR +IG V QE++LF TI +NI P+ +++I +
Sbjct: 390 EILIDGKPIESYPLETLRSQIGVVLQESFLFSSTIRDNIAYGRPDVSMKEIIAAARRAQA 449
Query: 455 HDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLV 514
HDFI +LP GY+T GE G LS G++Q I++ARA+L +P I+ILD+A S+VD KTE +
Sbjct: 450 HDFIAELPDGYDTVLGERGLGLSGGQKQRIAIARAILMNPSILILDDATSAVDMKTEHKI 509
Query: 515 QNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELL-SRKGYFYKLYTS 573
Q A ++M+GRT+ IIAHR+S + AD+++V+D G++ E G+ LL ++KG + ++Y
Sbjct: 510 QAAFREVMKGRTTFIIAHRISSVKQADEILVLDGGKVCERGTHHTLLQNKKGLYRRIYDI 569
Query: 574 QMQE 577
Q ++
Sbjct: 570 QSKD 573
>gb|AAD01950.1| (AF033015) ABC transporter homolog Z [Listeria monocytogenes]
Length = 590
Score = 339 bits (859), Expect = 7e-92
Identities = 185/565 (32%), Positives = 326/565 (56%), Gaps = 14/565 (2%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAIDH---YII----PGRYKELGFIAMLYLLSL--VA 74
L ++++++V + + +P + A+ Y++ G + FI ++++L L V
Sbjct: 22 LFVILIAVVFATYLQVKAPQYIGNAVQELGDYVVNLMQTGVDDKSDFIHIIWMLILCYVL 81
Query: 75 QWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVND 134
T +Q+ K +R L K+ + ++ FF +++ G+++SR +D + +++
Sbjct: 82 LAAATFIQSIIMTGVAGKSTNRMRIGLFRKMEKLSIRFFDSRNDGEMLSRFTSDLDNISN 141
Query: 135 VLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
L L+ L ++ + G+I+ M +V+L VTL S P +IIA K R+ +
Sbjct: 142 TLNQALIQVLSNVALMIGVIIMMFQQNVELAFVTLISAPFAIIIATVIIRKARKFVDIQQ 201
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
++ ++ ++E ++G + I G E++ F K + A + +Y G+ +P+M
Sbjct: 202 DELGVLNGYIDEKISGQKIIITNGLEEETIDGFVKQNNIVKNATYKGQVYSGLLFPMMQG 261
Query: 255 ASLLSVIVVIAYGGYLAYKG----AVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALA 310
SLL+ +VI +GG+LA G ++G++V F+QY+Q+F P+ + S Y LQ A+
Sbjct: 262 ISLLNTAIVIFFGGWLALNGDLERTAALGLIVMFVQYSQQFYMPLTQISSQYSLLQLAIT 321
Query: 311 ALERIYEILDDENVEDYEGI-SVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVA 369
R+ E+ +E + E + +++ + ++ +V F Y+ +PVLKDV++ + VA
Sbjct: 322 GARRVSEVFAEEEEVERENLQTIDGINKGVKLDHVDFAYDPAKPVLKDVSIDVSKGKMVA 381
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
+VG TG+GKTT+ NL+ RFY+ G IL+D ID + I SLRK++G V Q++ LF GTI
Sbjct: 382 LVGPTGSGKTTVMNLLNRFYNVDGGAILFDDIDIRDIRLDSLRKQVGIVLQDSVLFTGTI 441
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
+NI+ PEA +++VI K+ IHDFIM L KGYET + + SVG++QL+S+AR
Sbjct: 442 RDNIVFGKPEASDDEVINAAKQANIHDFIMNLEKGYETEISDENNIFSVGQKQLMSIART 501
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++ +P ++ILD A S+VD TE +Q AM ++ GRTS +IAHRL AD ++V+ G
Sbjct: 502 IITNPSLLILDGATSNVDTVTESRIQKAMDNVISGRTSFVIAHRLKTILDADHIVVLHQG 561
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQ 574
++E+G+ EL+ +G++ +LY +Q
Sbjct: 562 EVIEQGNHDELMKAEGFYSELYHNQ 586
>emb|CAB66302.1| (AL136519) ABC transporter protein, ATP-binding component.
[Streptomyces coelicolor A3(2)]
Length = 1243
Score = 338 bits (858), Expect = 9e-92
Identities = 183/553 (33%), Positives = 318/553 (57%), Gaps = 2/553 (0%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTT 80
R L I + + A L P ++R ID + + ++L L++++AQW T
Sbjct: 674 RAPLLISLALVAVDAGMGLLLPVLIRNGIDDGVTQAALGAVWASSLLGLVAVLAQWAAQT 733
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
+ T G+++L +LR ++ ++ + LD+++ + TG +++R+ D + ++ L +GL
Sbjct: 734 GEIRMTGRTGERILYSLRLKIFAQLQRLGLDYYERELTGRIMTRMTTDVDALSTFLQTGL 793
Query: 141 LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKI 200
+ S+++ GI+VA+L++DV+L L+ ++P ++I +F +AY R++++ +
Sbjct: 794 VTAFVSVVTFFGIMVALLVIDVELALIVFATLPPLIIATYFFRKASVKAYELARERVSTV 853
Query: 201 SSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSV 260
++ ++ESVAG+ ++AF +E+D + F++ S +A +R + +++P + + S +
Sbjct: 854 NADLQESVAGLRIVQAFRRERDGGRRFAERSDSYRQARIRGQWLISVYFPFVQLLSSAAA 913
Query: 261 IVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEIL- 319
V+ GG ++ G +VA++ Y F P+ + ++D Q A +L RI E+L
Sbjct: 914 AAVLVVGGARIDDATLTTGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRIQELLR 973
Query: 320 DDENVEDYEGIS-VEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGK 378
+ + E S V L+GEI F +V F Y L ++L IP VA VG+TGAGK
Sbjct: 974 EPTSTRAAEKPSEVTALRGEIAFEDVRFRYGDDEAALTGIDLRIPAGQTVAFVGETGAGK 1033
Query: 379 TTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANP 438
+T+ L+ RFYDPT G + DG D + + S R R+G VPQE YLFPGT+ + I P
Sbjct: 1034 STLVKLVARFYDPTDGRVTVDGRDLRDLDLTSYRHRLGVVPQEAYLFPGTVRDAIAYGRP 1093
Query: 439 EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVI 498
+A + V + +G H+ I L GY E G+ LS G+RQLI+LARA L DPD+++
Sbjct: 1094 DATDAQVEAAARAVGAHEMIATLTGGYLHEVAERGRNLSAGQRQLIALARAELVDPDVLL 1153
Query: 499 LDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPG 558
LDEA +++D TE V A ++ RT++++AHRL+ AD+V+V+D GR+ E+G+
Sbjct: 1154 LDEATAALDLATEAQVNQATDRIAGRRTTLVVAHRLTTAARADRVVVMDGGRVAEDGTHD 1213
Query: 559 ELLSRKGYFYKLY 571
ELL+ G + +L+
Sbjct: 1214 ELLALDGRYARLW 1226
Score = 284 bits (719), Expect = 2e-75
Identities = 173/554 (31%), Positives = 297/554 (53%), Gaps = 11/554 (1%)
Query: 28 VVSIVGSALANLAS----PYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQT 83
VV +G++L +A P I +V ID +I + +++ A L + + + + T ++
Sbjct: 22 VVLALGASLGGMAVMAFVPLITKVIIDD-VIGDKTRDMAVWAGLLIGAALVVYVLTYIRR 80
Query: 84 FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGG 143
+Y V +LR+ ++ I + + STG +V R +D ++ +L L
Sbjct: 81 YYGGRLALDVQHDLRTDMYGTITRLDGRRQDELSTGQVVGRATSDLQLIQGLLFM-LPMT 139
Query: 144 LGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSV 203
+G++L +V M L + LTLV L P + IA ++ A + + A ++ V
Sbjct: 140 IGNVLLFLISLVIMAWLSLPLTLVALAVAPALWFIARRSRTRLHPATWYAQAQAAAVAGV 199
Query: 204 VEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVV 263
V+ SV+G+ ++ FG+E+ + +V + LR + P + L + +
Sbjct: 200 VDGSVSGVRVVKGFGQEEQETGKLREVGRKLFAGRLRTIRLNATYTPALQAVPALGQVAM 259
Query: 264 IAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDEN 323
+A GG+LA +G +++G VAF Y + GP+ + + Q A A ER+ E++D E
Sbjct: 260 LALGGWLAVRGHITLGTFVAFSTYLAQLVGPVRMLAMVLTVGQQARAGTERVLELIDTEP 319
Query: 324 -VEDYEGISVEKLKGEIEFRNVWFEYEKG----RPVLKDVNLYIPPASKVAIVGKTGAGK 378
+ED +EF +V F Y+ G RPVL ++ I +A+VG +G+GK
Sbjct: 320 AIEDGTKTLPADAPATVEFDDVAFGYDTGDGEPRPVLDGLSFEIRAGETLAVVGSSGSGK 379
Query: 379 TTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANP 438
+T++ L+ RFYD T+G +L G D ++++ SLR +G VP++++LF T+ NI P
Sbjct: 380 STVSLLLPRFYDVTRGAVLVGGHDVRELTLDSLRAAVGLVPEDSFLFSDTVRANIAYGRP 439
Query: 439 EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVI 498
+A +E+V + H FI +LP GY T+ GE G LS G+RQ ++LARA+L DP +++
Sbjct: 440 DATDEEVEAAARAAQAHGFITELPDGYGTTVGEHGLTLSGGQRQRVALARAILTDPRLLV 499
Query: 499 LDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPG 558
LD+A S+VD + E + A+ ++M GRT+++IAHR S AD++ V+D GR+ + G+
Sbjct: 500 LDDATSAVDARVEHEIHEALKQVMRGRTTLLIAHRRSTLGLADRIAVLDRGRLADLGTHE 559
Query: 559 ELLSRKGYFYKLYT 572
EL R + +L T
Sbjct: 560 ELQERSALYRRLLT 573
>pir||G75142 abc transporter, ATP-binding protein PAB2147 - Pyrococcus abyssi
(strain Orsay) >gi|5457732|emb|CAB49222.1| (AJ248284)
ABC transporter, ATP-binding protein [Pyrococcus abyssi]
Length = 579
Score = 337 bits (856), Expect = 2e-91
Identities = 189/569 (33%), Positives = 320/569 (56%), Gaps = 2/569 (0%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
+ S++ L R + I + I+ + N P ++R AID + G YK
Sbjct: 2 RKSINQLIRLLSYLRGHAVHFLIGLFLIILMSYTNSIVPVLIRNAIDKGVSTGAYKVAIR 61
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+L LL V F+ + Q + LR I + ++FF +G L+S
Sbjct: 62 YGLLILLVGVLNGVFSLAGRYLLVKAAQYAVYYLRMDAFRAIQRHEMEFFDKTFSGQLIS 121
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
RI NDT + L + L SI + + M+ +++ LT+V L ++ ++V + +
Sbjct: 122 RITNDTERITRFLSFRVRMLLYSIFLIIISLYYMVRMNITLTMVALITIAIVVGLNTTYA 181
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
K+R Y + R + I+S+ ++AGI+TI++ E++V+ +FS+ + E ++
Sbjct: 182 MKVRPIYDKIRHQTGVIASIATGTIAGIKTIKSLSVEENVQTKFSQENEELYSLNVKAMK 241
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
++ + L++ + YGG + +++G +VAF+ Y P+ +
Sbjct: 242 ITALYGNAPFLVLGLAMSTMFYYGGKAIIQNTLTVGELVAFLTYMLTMMWPLRALGFTIG 301
Query: 304 SLQSALAALERIYEILDD--ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLY 361
+Q +LAA R+++++D ++++ + + + +GEIEFR+VW Y GR VLK V+
Sbjct: 302 DIQRSLAAASRLFDVIDSAPKSIDPPDAVEISNPRGEIEFRDVWLTYHTGRTVLKGVSFK 361
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
+ P KV I G G+GK++I LI RFY PTKGE+L DG++ KI ++LRK + YVPQE
Sbjct: 362 VKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEVLIDGVNVAKIKTENLRKIVAYVPQE 421
Query: 422 TYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
++F +I ENI +A P A +E+V R K IHDFI LPKGY+T GE G LS G+R
Sbjct: 422 PFIFNRSIRENIALAKPNATQEEVERAAKIAKIHDFIASLPKGYDTVVGEKGITLSGGQR 481
Query: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFAD 541
Q I+LARAML +P IV+LD+ +S++D +TE+ + + ++++ +T++I++ RLS+ + D
Sbjct: 482 QRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVEDLKEILQDKTALIVSQRLSLVKLVD 541
Query: 542 KVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
+VIV+ DG+IVE+G P EL+ + G F ++
Sbjct: 542 RVIVMKDGKIVEDGKPEELIKKGGIFSEM 570
>dbj|BAB06054.1| (AP001515) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 599
Score = 335 bits (849), Expect = 1e-90
Identities = 193/587 (32%), Positives = 324/587 (54%), Gaps = 8/587 (1%)
Query: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE 60
++ K ++ KR + A + L + + + + A L P I+++ ID Y+ P RY
Sbjct: 9 LSSKEQRTVFKRLLSYAAHYKGQLMVAFLLLFIATGAQLLGPIIVKIFIDDYLTP-RYFP 67
Query: 61 LGFIAML---YLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS 117
+ +L YL+ + Q F + +++ LR + + + L FF
Sbjct: 68 TDVLFLLGAGYLVLHLTAVIIDYYQLFLFQKVALSIVQRLRIDVFSSVQRLGLSFFDQTP 127
Query: 118 TGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
G LVSRI NDT + ++ V+ L + +I+ L GI AM L+V L + L +PL+
Sbjct: 128 AGGLVSRITNDTESIKELYVTVLATFVQNIIFLIGIFAAMFYLNVTLAIYCLVLLPLIFA 187
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
+ + R Y + +K++ ++ + ES+ G+ I+ F +E+ + KEFS ++ E A
Sbjct: 188 LMQVYRKYSSRFYADMSEKLSLLNGRINESIQGMAIIQMFRQERRMRKEFSAINDEHFLA 247
Query: 238 YLRVAIYMGIFW-PLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
++ G+ P +++ S+L+++++++Y G ++ AV IGVV AF+ Y RF P+N
Sbjct: 248 GMKSMKLDGLLLRPAVDVLSILALMLILSYFGIMSMDTAVEIGVVYAFVNYLDRFFEPVN 307
Query: 297 NVVSMYDSLQSALAALERIYEILDD-ENVEDYEGISVEKLKGE--IEFRNVWFEYEKGRP 353
++ Q A+ + R+++++D E D EG + GE +EFRNV F Y+
Sbjct: 308 QMMMRLSMFQQAIVSAGRVFKLMDHRELAPDREGNEHPAIIGEGNVEFRNVSFSYDGKTN 367
Query: 354 VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRK 413
VLK+++ + VA+VG TG+GKT+I N++MRFY GEIL DG LR
Sbjct: 368 VLKNISFTVKKGETVALVGHTGSGKTSIINVLMRFYPLQDGEILIDGKPLTSFENNELRA 427
Query: 414 RIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAG 473
++G V Q+ +L+ GTI NI + + ++ + R + FI +L GYET E G
Sbjct: 428 KVGLVLQDPFLYTGTIASNIRLYDQAISDDRIKRAASFVRADGFIERLSHGYETKVTERG 487
Query: 474 KLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHR 533
S G+RQL+S AR M+++P I+ILDEA +SVD +TE+ +Q A+ ++ +GRT+I IAHR
Sbjct: 488 ATFSSGQRQLLSFARTMVREPAILILDEATASVDTETEEAIQEALERMKQGRTTIAIAHR 547
Query: 534 LSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
LS + AD+++V+ G IVE G+ EL+++KG + K+Y Q + G
Sbjct: 548 LSTIKDADQILVLHQGEIVERGTHDELIAKKGLYQKMYVLQKGDEQG 594
>dbj|BAB10828.1| (AB016892) ABC transporter-like protein [Arabidopsis thaliana]
Length = 655
Score = 333 bits (846), Expect = 2e-90
Identities = 189/517 (36%), Positives = 295/517 (56%), Gaps = 7/517 (1%)
Query: 66 MLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRI 125
++ LL +V T L+ + ++V+ LR L ++ + F+ TG+L+SR+
Sbjct: 132 VIILLIVVIGSICTALRAWLFNSASERVVARLRKDLFRHLMHQEIAFYDVTKTGELLSRL 191
Query: 126 INDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGK 185
DT ++ + + L L ++ + + M KLTL+ L VP++ + FG
Sbjct: 192 SEDTQIIKNAATTNLSEALRNVTTALIGVGFMFTSSWKLTLLALVVVPVISVAVKQFGRY 251
Query: 186 MRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYM 245
+R T+ A +S+ EES + T+R+F KE + ++SK ET+K L+ A+ +
Sbjct: 252 LRELSHTTQAAAAVAASIAEESFGAVRTVRSFAKESYMVSQYSKKVDETLKLGLKQAVLV 311
Query: 246 GIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 305
G+F+ +N A LSVI V++YG YL G++++G + +FI Y+ ++++ S+Y +
Sbjct: 312 GLFFGGLNAAFTLSVITVVSYGAYLTIYGSMTVGALTSFILYSLTVGSSVSSLSSLYTTA 371
Query: 306 QSALAALERIYEILDDENVEDYEG--ISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNL 360
A A R+++ILD + G V G++E +VWF Y RP +LK ++L
Sbjct: 372 MKAAGASRRVFQILDRVSSMSSSGDKCPVGNPDGDVELNDVWFAY-PSRPSHMILKGISL 430
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+ P SKVA+VG +G GKTTIANLI RFYDP KG+IL +G+ +IS + L K+I V Q
Sbjct: 431 RLTPGSKVALVGPSGGGKTTIANLIERFYDPLKGKILLNGVSLMEISHQYLHKQISIVSQ 490
Query: 421 ETYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
E LF ++ ENI + EA D+ K H+FI P Y T GE G LS G
Sbjct: 491 EPILFNCSVEENIAYGFDGEASFTDIENAAKMANAHEFIEAFPDKYNTVVGERGLRLSGG 550
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
++Q I++ARA+L +P +++LDEA S++D ++E LVQ+AM LM GRT ++IAHRLS +
Sbjct: 551 QKQRIAIARALLTNPSVLLLDEATSALDAESEYLVQDAMDSLMAGRTVLVIAHRLSTVKT 610
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQ 576
AD V V+ DG + E+G+ ELLS G + L Q+Q
Sbjct: 611 ADCVAVISDGEVAEKGTHDELLSLNGIYTNLVKRQLQ 647
>gb|AAF67494.1|AF170880_1 (AF170880) NovA [Streptomyces spheroides]
Length = 635
Score = 331 bits (839), Expect = 2e-89
Identities = 194/570 (34%), Positives = 330/570 (57%), Gaps = 11/570 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L+R + R LA+V + + S+L +ASP++LR +D I GR L +A+ +
Sbjct: 26 LRRIFRLFRPYRGRLAVVGLLVGASSLVAVASPFMLREILDTAIPQGRTGLLSLLALGMI 85
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
L+ V F +QT + GQ+V+ +LR+ ++ ++ + L FF TG++ SRI ND
Sbjct: 86 LTAVLSSVFGVVQTLISTTVGQRVMHDLRTAVYAQLQRMPLAFFTRTRTGEVQSRIANDI 145
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
+ + S + ++ ++ +VAML LD +LT+V+L +P+ V I+ G + +R
Sbjct: 146 GGMQATVTSTATSLVSNLTAVIATVVAMLALDWRLTVVSLLLLPVFVWISRRVGRERKRI 205
Query: 190 YRETRQKIAKISSVVEES--VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGI 247
+ ++++A +++ V ES V+GI R G+ + + F++ S + L V M
Sbjct: 206 TLQRQKQMATMAATVTESLSVSGILLGRTMGRADSLTRSFAEESERLVD--LEVRSNMAG 263
Query: 248 FWPLMNIASLLSVIVVIAY--GGYLAYKGA--VSIGVVVAFIQYAQRFRGPINNVVSMYD 303
W + I +++ + + Y G++ G VSIG +VAF+ Q P +++
Sbjct: 264 RWRMSVIGIVMAAMPAVIYWAAGFVLQSGGTVVSIGTLVAFVSLQQGLFRPAVSLLPTGV 323
Query: 304 SLQSALAALERIYEILD--DENVEDYEGISVEKLKGEIEFRNVWFEYE-KGRPVLKDVNL 360
+Q++LA +RI+E LD + E ++++K++GE+ F V F YE K L ++L
Sbjct: 324 QMQTSLALFQRIFEYLDLPVDITEPERPVALDKVRGEVRFDGVDFSYEEKDGNTLHGLDL 383
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+P +A+VG TG+GK+T++ L+ R YD T G +L DG+D + ++ +L + +G V Q
Sbjct: 384 TVPAGGSLAVVGPTGSGKSTLSYLVPRLYDVTGGRVLLDGVDVRDLAFDTLARAVGVVSQ 443
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
ETYLF ++ +N+ A P+A +E++ + + IH+ I+ LP GY+T GE G S GE
Sbjct: 444 ETYLFHASVADNLRFAKPDATDEEIEKAARAAQIHEHIVTLPDGYDTLVGERGYRFSGGE 503
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++AR +L+DP +++LDEA S++D +TE VQ A+ L EGRT+I IAHRLS R A
Sbjct: 504 KQRLAIARTILRDPPVLVLDEATSALDTRTEHAVQQAIDSLSEGRTTITIAHRLSTVRDA 563
Query: 541 DKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
D+++V+D GRI E G+ EL+ R G + L
Sbjct: 564 DQIVVLDAGRIAERGTHEELIDRDGRYAAL 593
>emb|CAC13096.1| (AL445503) putative ABC transporter ATP-binding protein
[Streptomyces coelicolor A3(2)]
Length = 600
Score = 329 bits (834), Expect = 6e-89
Identities = 193/570 (33%), Positives = 325/570 (56%), Gaps = 11/570 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
++R +K R LA+V + + ++L ++A+P++L+ +D I GR L +A+ +
Sbjct: 22 VRRILKLFRPYRGRLAVVGLLVGAASLVSVATPFLLKEILDVAIPEGRTGLLSLLALGMI 81
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
V F LQT + GQ+V+ +LR+ ++ ++ Q +L FF TG++ SRI ND
Sbjct: 82 FGAVLTSVFGVLQTLISTTVGQRVMHDLRTAVYGRLQQMSLAFFTRTRTGEVQSRIANDI 141
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
+ + S + ++ S+ IVAM++LD +LT+V+L +P+ V I+ G + R+
Sbjct: 142 GGMQATVTSTATSLVSNLTSVVATIVAMVVLDWRLTVVSLLLLPVFVWISRRVGRERRKI 201
Query: 190 YRETRQKIAKISSVVEES--VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGI 247
++++A +++ V ES V+GI R G+ + + F+ S + L V M
Sbjct: 202 TTRRQKQMAAMAATVTESLSVSGILLGRTMGRSDSLTRAFADESESLVD--LEVRSNMAG 259
Query: 248 FWPLMNIASLLSVIVVIAY--GGYLAYKGA--VSIGVVVAFIQYAQRFRGPINNVVSMYD 303
W + I +++ + + Y G G VS+G +VAF+ Q P +++S
Sbjct: 260 RWRMAVITIVMAAMPAVIYWTAGIALQLGGPDVSLGTIVAFVSLQQGLFRPTVSLLSTGV 319
Query: 304 SLQSALAALERIYEILD--DENVEDYEGISVEKLKGEIEFRNVWFEYE-KGRPVLKDVNL 360
+QS+LA +RI+E LD + E + + ++ +KGE+ F V F Y KG PVL +++
Sbjct: 320 QIQSSLALFQRIFEYLDLPIDITERKDAVHLDHIKGEVRFEGVGFGYGGKGGPVLDGIDV 379
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+P S +A+VG TGAGK+T+ +L+ R YD T G + DG+D + + +L + +G V Q
Sbjct: 380 TVPAGSSLAVVGPTGAGKSTLGHLVPRLYDVTDGRVTLDGVDVRDLDFDTLARAVGVVSQ 439
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
ETYLF ++ EN+ A P+A + ++ + IHD I LP GY+T GE G S GE
Sbjct: 440 ETYLFHASVAENLRFAKPDATDAELEAAARAAQIHDHIAALPDGYDTVVGERGHRFSGGE 499
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++AR +L+DP +++LDEA S++D +TE VQ A+ L RT+I IAHRLS R A
Sbjct: 500 KQRLAIARTILRDPPVLVLDEATSALDTRTEAAVQGAIDALSANRTTITIAHRLSTVRDA 559
Query: 541 DKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
D+++V+D GR+ E+G+ LL++ G + L
Sbjct: 560 DRIVVLDSGRLAEQGTHEALLAQDGRYAAL 589
>pir||S77459 ABC-type transport protein slr1149 - Synechocystis sp. (strain PCC
6803) >gi|1652384|dbj|BAA17306.1| (D90905) ABC
transporter [Synechocystis sp.]
Length = 601
Score = 326 bits (826), Expect = 5e-88
Identities = 187/586 (31%), Positives = 328/586 (55%), Gaps = 25/586 (4%)
Query: 7 LSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY-------- 58
L +KR+ KE LA +V ++ A + P I+ A+ +
Sbjct: 21 LPYVKRYPKE-------LAAALVLLIPVAFSGAVQPLIIGQAVSLLREEPAWGFLDAMPL 73
Query: 59 -KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS 117
+ L + ++ +++V + F LQ F + GQ++ ++R L E + +++FF
Sbjct: 74 DRALHTLVIILAVTIVIRLLFLGLQGFIVQKMGQEITADVRQDLFEHVTSLSVNFFHRTP 133
Query: 118 TGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
G LV+RI +D + +V SG +G + I+S+ IIV + + +L L+ + + + +
Sbjct: 134 VGRLVTRITSDVEALGEVFASGAIGVVSDIVSILAIIVTIFWVQWQLALLLVGMLVPVTV 193
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
+ +YF + R+A + R+++++++S ++E+VAGI ++ F +E+ + F +V+ + +A
Sbjct: 194 LIIYFQQQYRKANYQAREELSRLNSQLQENVAGINVVQLFRREELNSRSFRRVNEKYRRA 253
Query: 238 YLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINN 297
+ + + SL+++ V+ GG+L + + GV+ AFI Y QR P+
Sbjct: 254 VDKTIFHDSAVSATLEWISLVAIAGVLGLGGWLILRDNLEFGVLAAFILYGQRLFNPLRQ 313
Query: 298 VVSMYDSLQSALAALERIYEILDDE-NVEDYEGISVEKLK-------GEIEFRNVWFEYE 349
+ QS A+ERI E++++ ++D I+ ++ GEI F NVWF Y+
Sbjct: 314 FADKFTMFQSGFTAIERIGELMEEPVEIKDQAVITPIEINGALRGSHGEICFENVWFGYK 373
Query: 350 KGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRK 409
VLK++N I P KVA+VG TGAGK++I L+ R +DP++G IL DGID +++S++
Sbjct: 374 PDEYVLKNLNFTIKPGEKVALVGPTGAGKSSIIRLLCRLHDPSRGRILVDGIDIRELSQQ 433
Query: 410 SLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSA 469
LR+ IG + Q+++LF G + NI + E E+V R + + I +LP+GY T
Sbjct: 434 QLRRFIGVILQDSFLFAGDVKRNITLGE-EYSLEEVQRAAQLTSVDRLIEELPQGYHTQL 492
Query: 470 GEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSII 529
E G LS G++QL++ AR +++P ++++DEA +S+D +TE +Q A++ L++ RTSII
Sbjct: 493 RERGSNLSGGQKQLLAFARVAIREPYVLVMDEATASLDVRTEADIQAALLHLLQDRTSII 552
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
IAHRLS R D++ V+ G IVE G+ +LL KG + LY QM
Sbjct: 553 IAHRLSTIRNVDRIFVLKHGEIVETGNHDQLLDLKGLYASLYQLQM 598
>pir||H69857 ABC transporter (ATP-binding protein) homolog yknU - Bacillus
subtilis >gi|2633803|emb|CAB13305.1| (Z99111) similar to
ABC transporter (ATP-binding protein) [Bacillus
subtilis] >gi|3282116|gb|AAC24906.1| (AF012285) YknU
[Bacillus subtilis]
Length = 585
Score = 322 bits (816), Expect = 8e-87
Identities = 179/540 (33%), Positives = 307/540 (56%), Gaps = 3/540 (0%)
Query: 42 PYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQL 101
P IL++ ID ++ +Y+ ++++ ++ +V + T + ++FG K + LR+ L
Sbjct: 36 PIILQITIDEIVLGRQYQLAAWVSLGFIAVMVLKGMATFFHQYLGDMFGIKSVYRLRNGL 95
Query: 102 HEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLD 161
+EK+ + + ++ TGDL+SR+ D + L GL + L +A + M
Sbjct: 96 YEKLQRLSFSYYDNAKTGDLMSRLTADVEGLRFFLSYGLAELIRFGLLVAISLSVMFYYS 155
Query: 162 VKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEK 221
V LTLVT+ +P + + F ++ A+R R+ AK+++ V+E+++GI T+++ +E
Sbjct: 156 VPLTLVTIAVLPFLAVAVYRFDKRVHPAFRGIRKSFAKLNTKVQENISGINTVKSLSRED 215
Query: 222 DVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVV 281
F+K + E YL+ + ++PLM ++ +++YGGYL + ++ G +
Sbjct: 216 FQISTFNKANAEYRAQYLQTSSIWSAYFPLMEFIGNTCIVALLSYGGYLVMQNQLNPGEL 275
Query: 282 VAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD-DENVEDY-EGISVEKLKGEI 339
VAF PI N+ + + A A+ ER+ +IL+ +E++ D+ + +KL G++
Sbjct: 276 VAFFSLVNYMMWPIMNLGFVINMFSQAKASGERLLDILEKEEDITDHPHALHKQKLTGDV 335
Query: 340 EFRNVWFEYEKGRP-VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILY 398
F+NV Y K + L +V+ + ++G TG+GK+++ L+ RFY P G I
Sbjct: 336 HFKNVSLAYGKEQTNALCNVSFEANSGKVIGLLGPTGSGKSSVTQLLTRFYSPVGGMITI 395
Query: 399 DGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFI 458
D S K+LR IG V QE++LF TI NI P+A EDVI K H+FI
Sbjct: 396 DHKPITDYSLKTLRSNIGVVLQESFLFSSTIRSNISYGRPDASMEDVIEAAKRAQAHNFI 455
Query: 459 MKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAM 518
M+LP GY+T GE G LS G++Q I++ARA+ +P I+ILD+A S+VD +TE +Q A+
Sbjct: 456 MELPDGYDTMLGERGMGLSGGQKQRIAIARAICLNPSILILDDATSAVDMQTEHSIQLAL 515
Query: 519 IKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
++M+ RT+ I+AHR+S + AD+++V + GRI E G+ ELL + GY+ K+Y Q ++V
Sbjct: 516 KEVMKNRTTFIVAHRISSLKHADEILVFNKGRIRERGTHHELLEKGGYYKKIYDLQYRDV 575
>gb|AAF71763.1|AF263912_2 (AF263912) NysG [Streptomyces noursei]
Length = 605
Score = 320 bits (811), Expect = 3e-86
Identities = 197/577 (34%), Positives = 304/577 (52%), Gaps = 13/577 (2%)
Query: 11 KRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYI------IPGRYKELGFI 64
+R + RR++A+ V VG + N P +L D +PG + F
Sbjct: 18 RRLVGLLRPHRRSVALAVSMGVGGIVLNAFGPLLLGRVTDLIADGVLGGVPGPAPGIDFA 77
Query: 65 A----MLYLLSL-VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTG 119
A +L LL+L V F Q + + LR EK+ + L F + G
Sbjct: 78 AIGRLLLVLLALYVVASLFMLAQGRLVASAVWRTIHELRRDAREKLTRLPLRHFDRQPAG 137
Query: 120 DLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIA 179
+L+SR ND + + L L + SI SL ++V ML++ L +V L SVP+ +IA
Sbjct: 138 ELLSRTTNDIDNLQQTLQQTLAELITSIFSLLTMLVLMLVISPSLAVVMLLSVPVSALIA 197
Query: 180 LYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYL 239
+ + Y +++ VEE G I+ F + E+ F + +A
Sbjct: 198 ARISKRAQPHYAAQWSANGTLNAHVEEVCTGHALIKGFDRRAAAEERFDACNDAVYRAAA 257
Query: 240 RVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
+ G P+M + L ++V G + G +++G V AFI YA++F PI +
Sbjct: 258 KAQFASGAMEPVMMFVANLGYVLVAVIGAWKVINGTLTLGDVQAFILYARQFSQPIVEIA 317
Query: 300 SMYDSLQSALAALERIYEILD--DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKD 357
S+ LQS +A+ +R++ +LD ++ + + + +G +EF +V F Y P++++
Sbjct: 318 SVAGRLQSGIASAQRVFTLLDAPEQAPDPLRPGTPARAEGRVEFTDVSFRYSPDTPLIEN 377
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
++L + P S VAIVG TGAGKTT+ NL+MRFY+P G IL DG D ++R LR R G
Sbjct: 378 LSLTVEPGSTVAIVGPTGAGKTTLGNLLMRFYEPDSGRILLDGTDTATMTRDDLRSRFGL 437
Query: 418 VPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLS 477
V Q+T+LF GTI ENI P A D+ + FI LP+GY+T + +S
Sbjct: 438 VLQDTWLFGGTIAENIAYGAPGACRADIEEAARATCADRFIRTLPQGYDTVLDDESGTVS 497
Query: 478 VGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSIT 537
GE+QL+++ARA L P +++LDEA SSVD +TE L+Q AM L GRTS +IAHRLS
Sbjct: 498 AGEKQLLTVARAFLARPAVLVLDEATSSVDTRTEVLIQRAMNSLRAGRTSFVIAHRLSTI 557
Query: 538 RFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
R AD ++V+D GRIVE+G+ +LL +G + +L+ ++
Sbjct: 558 RDADLIVVMDAGRIVEQGTHDQLLCAQGLYARLHAAR 594
>pir||H72425 ABC transporter, ATP-binding protein - Thermotoga maritima (strain
MSB8) >gi|4980528|gb|AAD35137.1|AE001691_11 (AE001691)
ABC transporter, ATP-binding protein [Thermotoga
maritima]
Length = 581
Score = 319 bits (810), Expect = 4e-86
Identities = 191/559 (34%), Positives = 302/559 (53%), Gaps = 13/559 (2%)
Query: 31 IVGSALA------NLASPYILRVAIDHYIIPG------RYKELGFIAMLYLLSLVAQWFF 78
+VG+ L+ + P +++ AID +++ R + A + L V +
Sbjct: 21 LVGTVLSLILTVMEILPPRLMKTAIDKFLVESTLSSFERLNGIVITAFIILGIRVLSFLV 80
Query: 79 TTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVS 138
++ T G +++ +R + ++ FF +G + +RI+NDT + + S
Sbjct: 81 GFASSYVTGYAGSRIVLLMRKDVFSHVISLPYSFFTGIPSGVVTTRIVNDTQNIQEFFSS 140
Query: 139 GLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIA 198
+ + +L L ++V+++ L +L +PL+VI L F RRAYR+ R +A
Sbjct: 141 VVTSVIMDVLLLGAVVVSLVQLSRELFGHVYYLLPLIVISILLFRYFDRRAYRKVRTNLA 200
Query: 199 KISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLL 258
++++ + E +AGI + EK E+EFS V+TE ++ + G+F PLM+ L
Sbjct: 201 RLNAFLAEHIAGINVTKILNLEKHKEREFSTVATEYYRSLMEQLYVFGVFRPLMDFLYFL 260
Query: 259 SVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEI 318
V +V+ YG + G + AF+ Y F P+ ++ YD +Q+++A+ E+I +
Sbjct: 261 GVSLVLWYGARYIANKTLGFGSLYAFVSYLDMFFRPLRDLSEKYDIIQNSMASSEKILNL 320
Query: 319 LDDENVEDYEGISVEKL-KGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAG 377
L +E K+ KG + F NVWF Y+ VLKD+NL P AIVG+TG G
Sbjct: 321 LKEEPEVIGNPNGPNKISKGRVRFENVWFSYDGKNWVLKDINLDFQPGKLYAIVGETGGG 380
Query: 378 KTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMAN 437
K+T+ +LI Y P KG I D I + + K +RK+I VPQ+ LF GTI++NI + +
Sbjct: 381 KSTLMSLINGLYIPQKGNIFIDEIPLLEYNLKLVRKQIAAVPQDVLLFSGTILDNIRLFD 440
Query: 438 PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIV 497
EE V+ K + D I +LP G E G LS GERQLI+LARA+L D I
Sbjct: 441 ESIPEERVLEALKRVHALDIIERLPGGVYYEIVERGTTLSAGERQLIALARAVLFDAKIF 500
Query: 498 ILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSP 557
ILDEA S+VD TE +Q A+ +L + RT I+IAHRLS + D+++VV +GRIVE+G+
Sbjct: 501 ILDEATSNVDVITETKIQEALEELSKDRTVIMIAHRLSTVKDVDEIVVVHNGRIVEKGNH 560
Query: 558 GELLSRKGYFYKLYTSQMQ 576
ELL ++G++Y LY Q +
Sbjct: 561 YELLEKRGFYYNLYKIQFE 579
>dbj|BAB04877.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 674
Score = 319 bits (809), Expect = 5e-86
Identities = 178/519 (34%), Positives = 297/519 (56%), Gaps = 8/519 (1%)
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+ + Y +V FF Q FY + ++++ LR L + + + FF G +VS
Sbjct: 151 LLLFYFGLMVVASFFQYGQRFYLQKAANRIIQRLRIDLFNHLSRLPVRFFDNMPAGKVVS 210
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
RI NDT + ++ V+ L SI+ + GI +AM LLDV+L + L +P++V+ + +
Sbjct: 211 RITNDTEAIRELYVAVLANFFTSIIYMIGIYIAMFLLDVRLAFICLGLIPILVLWIVLYR 270
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK---AYLR 240
R KI++I++ + E++ G+ I+AF +EKD F +++ + LR
Sbjct: 271 KYASAINHRIRSKISEINASMNENIQGMSIIQAFVREKDSADTFDRLNDSHYRDQVKLLR 330
Query: 241 VAIYMG--IFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNV 298
+ G + W L N+ + +I IA G L A+++GV+ AF+ Y R P+N +
Sbjct: 331 LNALTGHNLSWVLRNLV-FVGLIWSIA-GTSLGAGSALTLGVLYAFVDYVNRLFEPVNRI 388
Query: 299 VSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDV 358
V +L+ A A ER++E++D E E + ++ + KG++ F NV F Y++ VLK++
Sbjct: 389 VHQLPNLEQARVAGERVFELMDKEGTEVSDE-TIPRPKGDVVFDNVSFAYKENEKVLKNL 447
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+ P + +VG TG+GK++I NL+ RFYD +G+I DG D K+IS ++LR+ +G V
Sbjct: 448 TFHAKPGQTIGLVGHTGSGKSSIMNLLFRFYDSDEGQIRIDGQDIKEISPQALRQHMGIV 507
Query: 419 PQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
QE YLF GT+ N+ ++NP E + + + L +G + E G LS
Sbjct: 508 LQEPYLFTGTVASNLSLSNPAITREAMEEALRLVDGEHVFADLEQGLDEEVKEKGSTLSS 567
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQLIS ARA++ DP I++LDEA S++D +TE ++Q + L GRT+ +IAHRLS +
Sbjct: 568 GQRQLISFARALVADPAILVLDEATSNIDSETEAIIQRGLEALKRGRTTFVIAHRLSTIK 627
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
AD+++V+D G+I+E G+ EL+ ++G + ++Y Q QE
Sbjct: 628 NADQILVLDKGKIIESGTHDELMEQEGAYAQMYYLQNQE 666
>dbj|BAB04660.1| (AP001510) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 584
Score = 317 bits (804), Expect = 2e-85
Identities = 170/494 (34%), Positives = 284/494 (57%), Gaps = 3/494 (0%)
Query: 84 FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGG 143
++ + G K+L ++R L I + +L F+ + G+++SR+I+D +++GL+
Sbjct: 88 YFAQWIGNKILYDIRDHLFTHIQKLSLRFYSNRKVGEIISRVIHDVEQTKTFVMTGLMNI 147
Query: 144 LGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSV 203
+ ++ + M ++ LTLV + P YF K+R R Q +A +
Sbjct: 148 WLDMFTIIIALAIMFSMNAWLTLVAIAMFPFYGFSIKYFYAKLRHLTRVRSQALADVQGH 207
Query: 204 VEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVV 263
+ E V G+ IR+F E + +F+K + + + + + ++N + ++ ++V
Sbjct: 208 LHERVQGMSVIRSFALEDYEQTQFAKRNGTFLNRAIDHTKWNAKTFAVVNTVTDIAPLLV 267
Query: 264 IAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE- 322
I G + +G + AF+ Y +R P+ +V+ +L ++A+++R++E +D++
Sbjct: 268 IFVAACFVINGELEVGAMTAFVLYMERLYNPLRRLVNSSTTLTQSIASMDRVFEFIDEKY 327
Query: 323 NVEDYEG-ISVEKLKGEIEFRNVWFEYEKGR-PVLKDVNLYIPPASKVAIVGKTGAGKTT 380
++ D EG + +E++ G++ F +V F YEK P LKDV+ ++ VA VG +G GK+T
Sbjct: 328 DIVDKEGAVKLEEVHGDVTFDHVSFSYEKEETPALKDVHFHVKRGETVAFVGMSGGGKST 387
Query: 381 IANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEA 440
+ +LI RFYD + G IL DG D + +SLR +IG V QE LF ++ NILM P+A
Sbjct: 388 LISLIPRFYDVSSGRILIDGHDIRDYQVRSLRDQIGMVLQENILFSDSVRMNILMGKPDA 447
Query: 441 KEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILD 500
EE+VI K HDFIM LP GY+T GE G LS G++Q +++AR LK+P I+I D
Sbjct: 448 TEEEVIAAAKAANAHDFIMNLPNGYDTEVGERGVKLSGGQKQRVAIARVFLKNPPILIFD 507
Query: 501 EALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGEL 560
EA S++D ++E +Q AM KL + RT+ I+AHRLS AD++IVV++G IVE G+ EL
Sbjct: 508 EATSALDLESEHYIQEAMEKLAKNRTTFIVAHRLSTITHADRIIVVENGEIVESGTHDEL 567
Query: 561 LSRKGYFYKLYTSQ 574
+S G + KL+ Q
Sbjct: 568 MSCNGVYKKLFEVQ 581
>pir||H69828 ABC transporter (ATP-binding protein) homolog yheH - Bacillus
subtilis >gi|2226165|emb|CAA74449.1| (Y14080)
hypothetical protein [Bacillus subtilis]
>gi|2633307|emb|CAB12811.1| (Z99109) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 673
Score = 316 bits (802), Expect = 3e-85
Identities = 184/523 (35%), Positives = 297/523 (56%), Gaps = 11/523 (2%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKST 118
K + + LY LV FF Q + ++ ++++ +R + I + + +F
Sbjct: 147 KGMVLLICLYGGLLVFSVFFQYGQHYLLQMSANRIIQKMRQDVFSHIQKMPIRYFDNLPA 206
Query: 119 GDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVII 178
G +V+RI NDT + D+ V+ L + S + + GI A+ LLDVKL V L VP++ +
Sbjct: 207 GKVVARITNDTEAIRDLYVTVLSTFVTSGIYMFGIFTALFLLDVKLAFVCLAIVPIIWLW 266
Query: 179 ALYFGGKMRRAYRETRQKIAKISSVVE----ESVAGIETIRAFGKEKDVEKEFSKVSTET 234
++ + RR QKI I+S + ES+ G+ I+AF +K+ +EF +++
Sbjct: 267 SVIY----RRYASYYNQKIRSINSDINAKMNESIQGMTIIQAFRHQKETMREFEELNESH 322
Query: 235 IKAYLRVAIYMGIF-WPLMNIASLLSVIVVIAY--GGYLAYKGAVSIGVVVAFIQYAQRF 291
R+ + L+N+ L+ + +I + G L G VSIGV+ AF+ Y R
Sbjct: 323 FYFQNRMLNLNSLMSHNLVNVIRNLAFVCLIWHFGGASLNAAGIVSIGVLYAFVDYLNRL 382
Query: 292 RGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKG 351
PI +V+ + L+ A + R++E+L+++N E+ + E+ G +EFR+V F Y++G
Sbjct: 383 FQPITGIVNQFSKLELARVSAGRVFELLEEKNTEEAGEPAKERALGRVEFRDVSFAYQEG 442
Query: 352 RPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
VLK ++ VA+VG TG+GK++I NL+ RFYD KG++L DG +SR+ L
Sbjct: 443 EEVLKHISFTAQKGETVALVGHTGSGKSSILNLLFRFYDAQKGDVLIDGKSIYNMSRQEL 502
Query: 412 RKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
R +G V Q+ YLF GTI N+ + + EE++ +++G + KLPKG E
Sbjct: 503 RSHMGIVLQDPYLFSGTIGSNVSLDDERMTEEEIKNALRQVGAEPLLKKLPKGINEPVIE 562
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G LS GERQLIS ARA+ DP I+ILDEA + +D +TE ++Q A+ + +GRT+ +IA
Sbjct: 563 KGSTLSSGERQLISFARALAFDPAILILDEATAHIDTETEAVIQKALDVVKQGRTTFVIA 622
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
HRLS R AD+++V+D G IVE G+ EL++ +G +Y++Y Q
Sbjct: 623 HRLSTIRNADQILVLDKGEIVERGNHEELMALEGQYYQMYELQ 665
>pir||A75590 ABC transporter, ATP-binding protein - Deinococcus radiodurans
(strain R1) >gi|6460730|gb|AAF12435.1|AE001863_60
(AE001863) ABC transporter, ATP-binding protein
[Deinococcus radiodurans]
Length = 602
Score = 315 bits (799), Expect = 8e-85
Identities = 191/575 (33%), Positives = 316/575 (54%), Gaps = 10/575 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFI--AML 67
L+R + A R + V++ + S+ L P + ID + + G + +L
Sbjct: 25 LRRLLAYARPYRLPFVLGVLATLISSGLGLVFPRLFGTLIDASFLKVGSTDTGPLDRTVL 84
Query: 68 YLLSLVA-QWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRII 126
LL + A F Q + G V+ +LR L +L + FF TGDL SR+
Sbjct: 85 SLLGIFALSACFGAAQAYLLARVGAGVVADLRRALFSHLLSLSPRFFGNHRTGDLTSRLT 144
Query: 127 NDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKM 186
+D V V + L +L G ++ ++ +L+L+TL +PL++ A+ G ++
Sbjct: 145 SDVGTVQAVTSTALAQLASQGFTLIGSVLLLVQTSPRLSLLTLAIIPLVIGTAVTIGRRI 204
Query: 187 RRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG 246
RR RE + +A + EE+++G+ +++F E E+ + + + +A LR A
Sbjct: 205 RRVSREVQDAVAAANGQAEEAISGVRVVQSFTAEGLEEERYGQGVLASFRAALRRARLQA 264
Query: 247 IFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQ 306
+ +M+ + ++ +V+ +GG GA++ G +V F+ YA + G + + +++ Q
Sbjct: 265 LMTGVMSFLTFGALALVLWFGGRQVMSGALTPGNLVTFLFYALQVGGTVAALTGVFNQFQ 324
Query: 307 SALAALERIYEILDDENVEDYEGIS----VEKLKGEIEFRNVWFEYEKGRPVLKDVNLYI 362
AL A RI+E+LD+ + D G + + + +G + F +V F Y G P L+D+ +
Sbjct: 325 EALGASSRIFELLDERS--DLPGPAAPRPLSRAEGRVRFVDVGFTYA-GAPALQDITFDV 381
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
P VA+VG +GAGKTT+ NLI RF+D T G + DG D + + LR+++G VPQET
Sbjct: 382 PAGQVVALVGPSGAGKTTLVNLIPRFWDVTAGRVEVDGHDVRAYALADLRRQVGLVPQET 441
Query: 423 YLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
LF GT+ ENIL P A + +V H+FI +L GY GE G LS G+RQ
Sbjct: 442 LLFSGTVAENILYGRPGASQAEVEAAAHAAHAHEFICELEGGYGAVVGERGVKLSGGQRQ 501
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
+++ARA+LKDP I+ILDEA S++D ++E LVQ A+ +LM GRT+ ++AHRLS R AD+
Sbjct: 502 RVAIARAILKDPRILILDEATSALDNESEALVQAALERLMVGRTTFVVAHRLSTIRSADR 561
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
++V+D GR+V +G+ L++ G + +LY Q ++
Sbjct: 562 ILVMDAGRVVADGTHEGLMAAGGLYRELYELQFRQ 596
>pir||S75806 hemolysin secretion protein hlyB - Synechocystis sp. (strain PCC
6803) >gi|1653351|dbj|BAA18265.1| (D90913) HlyB family
[Synechocystis sp.]
Length = 1011
Score = 312 bits (791), Expect = 7e-84
Identities = 185/557 (33%), Positives = 310/557 (55%), Gaps = 4/557 (0%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTT 80
R L +V V+ L LA+P ++++ ID I+ L + + + + + +T
Sbjct: 449 RYILLLVFVASFFVQLFGLANPLMIQIIIDKVIVQNSKDTLQVLGIALVSIAIFEALLST 508
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
L+T+ ++ +L S++ + +L+ L +F+ + G++ +R+ N+ + + L
Sbjct: 509 LRTYLFVDTTNRIDMSLGSEIIDHLLRLPLRYFENRPVGEISTRVNELENIRQFLTGTAL 568
Query: 141 LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKI 200
L S+ S+ I+V M++ LT V L VP+ VI+ L F +RR R ++ A+
Sbjct: 569 TVVLDSVFSVVYIVV-MIIYSPLLTAVALGIVPIFVILTLVFSPLIRRQLRLKAERNAQT 627
Query: 201 SSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSV 260
S + E ++GI+T++A E ++ + + A I + + + LS
Sbjct: 628 QSYLVEVMSGIQTVKAQNIELRSRWQWQDKYSRYVGAGFNTVITSTLASSSSHFLNQLSG 687
Query: 261 IVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD 320
++V+ G L G +++G ++AF A PI + ++ + Q +LER+ +I+D
Sbjct: 688 LLVLWVGASLVLDGDLTLGQLIAFRIIAGYVTSPILRLTQLWQNFQETALSLERLADIVD 747
Query: 321 --DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAIVGKTGAG 377
E+ D + I + ++ GE++F NV F ++K P+ L ++NL PP + VA+VG++GAG
Sbjct: 748 TPQESERDRQNIPMPEIAGEVKFENVSFRFKKQGPLQLNNINLSFPPGTFVALVGQSGAG 807
Query: 378 KTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMAN 437
K+T+ L+ R Y+P G IL DG+D K+ SLR+++G VPQET LF GT+ ENI + N
Sbjct: 808 KSTLTKLLSRLYEPEGGRILVDGLDIGKVELYSLRRQVGVVPQETLLFEGTVQENIALTN 867
Query: 438 PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIV 497
P+A E +I K H+FIM LP GY T GE G LS G+RQ I++AR++L+ P I+
Sbjct: 868 PDATTEQIISAAKVASAHEFIMTLPNGYNTRVGERGATLSGGQRQRIAIARSVLQRPRIL 927
Query: 498 ILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSP 557
+LDEA S++D TEQ V + + T I HRLS R AD ++++D G +VE+GS
Sbjct: 928 VLDEATSALDYITEQQVCINLGDAFKDHTVFFITHRLSSVRSADVIVMMDQGSVVEQGSH 987
Query: 558 GELLSRKGYFYKLYTSQ 574
EL++ KG +Y LY Q
Sbjct: 988 DELMALKGRYYYLYQQQ 1004
>dbj|BAB04432.1| (AP001509) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 578
Score = 310 bits (785), Expect = 3e-83
Identities = 182/579 (31%), Positives = 312/579 (53%), Gaps = 9/579 (1%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGS---ALANLASPYILRVAIDHYIIPGRYK 59
+K + LK F LS + ++GS L L P + R +D + +
Sbjct: 2 EKQQQTSLKPFFSLILSTNIPKVALTFGLIGSLITTLVGLTIPLLTREMVDGFSLESLNT 61
Query: 60 ELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTG 119
L IA + ++ + Q L + GQK++ LR ++ K+L+ +++F ++G
Sbjct: 62 LL--IAAIIVV-FILQAVLDGLSMYALAYVGQKIVARLRERMWFKLLRLPVNYFDKNTSG 118
Query: 120 DLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIA 179
VSR++NDT +V D++ +G I+++ G ++ + ++D K+TL+ +VP+ V +
Sbjct: 119 QTVSRVVNDTGIVKDLISQHFPQFVGGIITIIGAVIILFIMDWKMTLLMFIAVPITVAVM 178
Query: 180 LYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYL 239
+ G +M + R + + A + V+++++ I ++A E+ EK+ + L
Sbjct: 179 VPLGMRMSKISRGLQDETANFTGNVQQTLSEIRLMKASNAEQTEEKKGLTGIEKLFSFGL 238
Query: 240 RVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
R + PLM + ++ ++++I YGG +G ++ G +VAF+ Y + PI +
Sbjct: 239 REGKIFALIAPLMYLVVMVVIVIIIGYGGIRVAEGTMTTGSLVAFLLYLFQIIFPITSFT 298
Query: 300 SMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVN 359
+ LQ A A ERI EILD E +G+ ++ I +NV F Y + PV++ V+
Sbjct: 299 MFFTQLQKAKGATERIIEILDIEEENGQQGLEMDISNKAIHVKNVSFAYNEEEPVIQKVS 358
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
+ P + VA G +G GKTT+ L+ RFY+PT GEIL +++S S RK+IGYV
Sbjct: 359 FDVEPGTMVAFAGPSGGGKTTMFGLLERFYEPTSGEILIGDTSIQELSMYSWRKQIGYVS 418
Query: 420 QETYLFPGTIMENI---LMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLL 476
Q++ + GTI EN+ L + ++ + V K FI + PKG +T GE G L
Sbjct: 419 QDSPMMVGTIRENLCYGLEDRDDIDDDRLWEVAKMAYADQFISEFPKGLDTEVGERGVKL 478
Query: 477 SVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSI 536
S G+RQ I++ARA L+DP I+++DEA +S+D ++E +VQ A+ +LMEGRT+ +IAHRLS
Sbjct: 479 SGGQRQRIAIARAFLRDPKILMMDEATASLDSQSEGIVQQALTRLMEGRTTFVIAHRLST 538
Query: 537 TRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
ADK+I ++ G+I G+ EL+ + + Q+
Sbjct: 539 IVNADKIIFIEKGQITGIGTHQELVQTHDLYREFAEQQL 577
>sp|P55469|Y4GM_RHISN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEIN Y4GM
>gi|2182416|gb|AAB91687.1| (AE000075) Y4gM [Rhizobium
sp. NGR234]
Length = 586
Score = 308 bits (780), Expect = 1e-82
Identities = 180/575 (31%), Positives = 309/575 (53%), Gaps = 3/575 (0%)
Query: 4 KSSLSLLKRFIKEALSERRT-LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG 62
KS+ SLL R + E + I + S+V A+ AS +I+R ++ ++ +++
Sbjct: 8 KSNQSLLMRLLAENFKHQAPWYGIAIGSMVVVAVMTSASAWIMRDVVNSTVVSKDIEKVF 67
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
+A+ + + T +Q+ + G ++ + + +L E +L+ L F+ + +L+
Sbjct: 68 GVAVTVAIIFAVKGLATYVQSIFLSKAGNNIIAHTQRRLFEHVLRQGLSFYSIYPSSELL 127
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
R+ N+ V V+ + + + SL G++ M++ L+LV+ P ++
Sbjct: 128 VRLTNNAQAVRSVIELVVTSFIRDLFSLMGLLAVMVIQQPLLSLVSAAVGPGAILGVRVL 187
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
K+R+ I +I V+E+ GI ++AF E + + K + + +A
Sbjct: 188 TRKVRKIMELEIASIGQIIQSVQETSTGIRIVKAFALEDFMRRRMDKYIGDVERRANSIA 247
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
P+M S ++ VIA G L + + G +++FI P + M
Sbjct: 248 RLEAASSPIMETLSGFAIAGVIALSGVLVLQQGNTPGELMSFITALLLAYEPAKRLARMR 307
Query: 303 DSLQSALAALERIYEILDD--ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNL 360
SL+SAL + +Y++ D E E I + + GEI F++V F Y+ G + +++N+
Sbjct: 308 ISLESALVGVRMMYQLADHPIELTEKNSAIPLPEGPGEIRFKDVNFSYKNGERLFQNLNV 367
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
P A+VG +GAGK++I NLIMR YDP G + DG D K ++ +SLR RIG+V Q
Sbjct: 368 TFPAGKTTALVGPSGAGKSSIINLIMRLYDPDVGSVTVDGHDLKDVTFRSLRDRIGFVGQ 427
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
+T+LF GTI NI + A +E++I K HDFIMK+P GY+T GE G LS G+
Sbjct: 428 DTFLFSGTIKYNISLGREGASDEEIIEAAKTANAHDFIMKMPHGYDTEVGENGIKLSGGQ 487
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q I++ARAML++ +I+I DEA S++D ++E ++ A+ +L RT+I+IAHRLS A
Sbjct: 488 KQRITIARAMLRNAEILIFDEATSALDSESEIQIRQALARLTRKRTTIMIAHRLSTVTAA 547
Query: 541 DKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
D ++V++ G++ E+G G LLS+ G + +LY Q+
Sbjct: 548 DNIVVMEGGQVAEQGPQGRLLSQDGVYRRLYELQL 582
>emb|CAB76004.1| (AL157916) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 627
Score = 305 bits (772), Expect = 1e-81
Identities = 191/562 (33%), Positives = 307/562 (53%), Gaps = 18/562 (3%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAML---YLLSLVAQWFFTT 80
+A+ V+ ++ A A P ++ AIDH + R + G + + YLL +A
Sbjct: 62 VALTVLLLLLQQAAVQAGPLLVAYAIDHAVPALRDDDHGPLIAVGAGYLLCSLAAGGLQY 121
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
Q VL +LR ++ ++DF + ++G L+SR D + ++L GL
Sbjct: 122 AFIAAAARVSQDVLLDLRGRIFRHAQALSVDFHERYTSGRLISRSTTDVESLRELLDEGL 181
Query: 141 LGGLGSILSLAGIIVAMLLLDVKLTLVTLTS-VPLMVIIALYFGGKMRRAYRETRQKIAK 199
+ ILS I +L LD+ L V + S VPL ++ LY RRA R RQ+
Sbjct: 182 QELVTVILSFVYIAALLLWLDLGLGAVAVASFVPLYALVRLY----QRRAGRVYRQRSTA 237
Query: 200 ISSVVE---ESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
I++V+ E++ GI +R+F +E + +F+ ++ + + M + + +
Sbjct: 238 IAAVIVKFVETMNGIRPVRSFRREAANDADFAVLNHRHERTNGDALLEMARYVVGSRLVA 297
Query: 257 LLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
+V ++ +G Y G +++GV+ A + Y +R PI+ + +S QSA A+LE+I
Sbjct: 298 NTAVAGIVLWGAYRVADGTLALGVLAAAVLYLRRLYDPIDRLGMFLNSYQSAAASLEKIA 357
Query: 317 EIL-------DDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVA 369
+L + ++ + E E+ F +V F Y G VL L +P VA
Sbjct: 358 GLLAQTPSVPEPTAPKELPPLESEHPGREVVFDSVSFGYRTGGEVLPRFGLTLPAGQTVA 417
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
+VG TGAGK+T+A L+ RFYDP+ G +L DG D + ++ LR+ + V QE +LF GT+
Sbjct: 418 VVGSTGAGKSTLAKLLARFYDPSAGRVLLDGTDLRDLAVPELRRGVVMVTQEAFLFSGTV 477
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
+NI + PEA E++ R K +G HDFI LP GY+T + G +S G+RQL++ ARA
Sbjct: 478 ADNIAIGRPEATREEIERAAKAIGAHDFIAALPDGYDTDVRKRGGRISAGQRQLVAFARA 537
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
+L DP ++ILDEA SS+D E+ VQ AM +++GRT+++IAHRLS AD+V+V++ G
Sbjct: 538 LLADPAVLILDEATSSLDIPGERAVQRAMTTVLKGRTAVVIAHRLSTVEIADRVLVMEHG 597
Query: 550 RIVEEGSPGELLSRKGYFYKLY 571
RIVE+G+P EL++ G F L+
Sbjct: 598 RIVEDGAPDELIAGTGRFADLH 619
>dbj|BAB07610.1| (AP001520) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 577
Score = 304 bits (771), Expect = 1e-81
Identities = 177/551 (32%), Positives = 308/551 (55%), Gaps = 17/551 (3%)
Query: 36 LANLASPYILRVAIDHYIIPGRYKELGF----IAMLYLLSLVAQWFFTTLQTFYTEVFGQ 91
+ LA P + ID + G ++ + + + +YLL+ V Q+ + T++ G
Sbjct: 28 ILELAFPLAVNQVIDRLLPEGNWQIIFWACVGLLFVYLLNTVMQY----VVTYWGHKLGI 83
Query: 92 KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLA 151
+ ++R +L E + + + ++ TG +SR+ D + +V G ++++L
Sbjct: 84 NIESDMRKKLFEHMQKLSFGYYDNNKTGHSISRLTKDLEEIGEVAHHGPEDVFVAVMTLV 143
Query: 152 GIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGI 211
G ML + +L + VP ++I A+YF KM +R Q + I++ VE+S+ GI
Sbjct: 144 GAFAIMLSIHWQLAVALFCVVPFIIIFAVYFNKKMTTTFRRMFQDVGDINARVEDSIGGI 203
Query: 212 ETIRAFGKEKDVEKEFSKVSTETIK----AYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
++AF E+ + +F+K + K +Y +A + + LM +LL+++V G
Sbjct: 204 RVVQAFANERYEQAQFAKNNQRYRKTKLASYKIMAQNVMANYVLMRSITLLTLLV----G 259
Query: 268 GYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE-NVED 326
+ G+++ G VAFI + P+ + ++ +S +A +R EILD E ++ED
Sbjct: 260 TWFVISGSLTYGEFVAFILLSNILIQPVQKINAVIESYPKGIAGFKRYTEILDTEPDIED 319
Query: 327 YEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIM 386
G ++G I++ V F Y+ VLK+++L I VA VG +GAGKTT+ +L+
Sbjct: 320 APGAKEWNIQGNIQYEGVRFGYDGMEDVLKNIDLTIRAGETVAFVGPSGAGKTTLCSLLP 379
Query: 387 RFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVI 446
RFY+ G I+ DG+D +++ +SLR +IG V Q+ +LF GT+ ENI N +A +E+++
Sbjct: 380 RFYEVKDGRIVVDGLDIREMKLESLRNQIGIVQQDVFLFSGTVKENIAYGNLQATDEEIM 439
Query: 447 RVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSV 506
++ + DFI+ P G ET GE G LS G++Q +S+AR LK+P I+ILDEA S++
Sbjct: 440 EAARKAKLDDFILSQPDGLETVIGERGVKLSGGQKQRLSIARMFLKNPPILILDEATSAL 499
Query: 507 DPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGY 566
D +TE +Q ++ +L +GRT+++IAHRL+ + AD++IVV I E+GS +LL G
Sbjct: 500 DTETELAIQQSLSELSKGRTTLVIAHRLATIKNADRIIVVTKEGIAEQGSHEQLLQTGGI 559
Query: 567 FYKLYTSQMQE 577
+ +L+ +Q E
Sbjct: 560 YARLHRAQFGE 570
>pir||D70031 ABC transporter (ATP-binding protein) homolog yvcC - Bacillus
subtilis >gi|1945644|emb|CAB08051.1| (Z94043)
hypothetical protein [Bacillus subtilis]
>gi|2635995|emb|CAB15487.1| (Z99121) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 589
Score = 303 bits (767), Expect = 4e-81
Identities = 184/576 (31%), Positives = 314/576 (53%), Gaps = 8/576 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY-KELG 62
KS L ++ LA + V + L +L P + + +D + + ++G
Sbjct: 9 KSKLKPFFALVRRTNPSYGKLAFALALSVVTTLVSLLIPLLTKQLVDGFSMSNLSGTQIG 68
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
IA+++ + Q + T+ GQK++ LR L +K+++ + +F T ++G+ V
Sbjct: 69 LIALVFFV----QAGLSAYATYALNYNGQKIISGLRELLWKKLIKLPVSYFDTNASGETV 124
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
SR+ NDT VV +++ + + G + I+S+ G + + +++ KLTL+ L VPL +I +
Sbjct: 125 SRVTNDTMVVKELITTHISGFITGIISVIGSLTILFIMNWKLTLLVLVVVPLAALILVPI 184
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETI-KAYLRV 241
G KM RET+ + A+ + ++ + + I ++A E DVE K+ ++ K +R
Sbjct: 185 GRKMFSISRETQDETARFTGLLNQILPEIRLVKASNAE-DVEYGRGKMGISSLFKLGVRE 243
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
A + PL+++ + +++ VI YGG G ++ G +VAFI Y + P+ + +
Sbjct: 244 AKVQSLVGPLISLVLMAALVAVIGYGGMQVSSGELTAGALVAFILYLFQIIMPMGQITTF 303
Query: 302 YDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLY 361
+ LQ ++ A ER+ EIL +E + G +E I+ V F Y+ + +LK+V+
Sbjct: 304 FTQLQKSIGATERMIEILAEEEEDTVTGKQIENAHLPIQLDRVSFGYKPDQLILKEVSAV 363
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
I AIVG +G GKTT+ L+ RFY PT G I S +S R+ IGYV QE
Sbjct: 364 IEAGKVTAIVGPSGGGKTTLFKLLERFYSPTAGTIRLGDEPVDTYSLESWREHIGYVSQE 423
Query: 422 TYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
+ L GTI ENI + + ++ + + +FI +LP ++T GE G +LS G+
Sbjct: 424 SPLMSGTIRENICYGLERDVTDAEIEKAAEMAYALNFIKELPNQFDTEVGERGIMLSGGQ 483
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
RQ I++ARA+L++P I++LDEA SS+D ++E+ VQ A+ LMEGRT+I+IAHRLS A
Sbjct: 484 RQRIAIARALLRNPSILMLDEATSSLDSQSEKSVQQALEVLMEGRTTIVIAHRLSTVVDA 543
Query: 541 DKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQ 576
D+++ V+ G I G+ EL++ G + Q++
Sbjct: 544 DQLLFVEKGEITGRGTHHELMASHGLYRDFAEQQLK 579
>gb|AAG11416.1|AF263455_1 (AF263455) TagA [Dictyostelium discoideum]
Length = 1702
Score = 302 bits (765), Expect = 7e-81
Identities = 166/543 (30%), Positives = 305/543 (55%), Gaps = 5/543 (0%)
Query: 29 VSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEV 88
+S + AL LA P + D Y+ G ++ + + L ++ L +
Sbjct: 1069 LSFIDVALG-LAVPLVAANIFD-YLYAGETGKISTTILTFALIIIGMIIVQFLSGILLAL 1126
Query: 89 FGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSIL 148
G +++ LR ++ +L+ ++ FF + TG+L+SR+ +D + V ++ + + I
Sbjct: 1127 AGHRIIARLRREMFASLLKQDMAFFNERKTGELMSRLASDVSSVRSIISDSIPHMIIQIA 1186
Query: 149 SLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESV 208
++ G ++ + ++ KL+LV L +P++++ + ++GG + + + +A ++ E++
Sbjct: 1187 TIGGTLIMLFIISWKLSLVVLCPLPILLVFSKFYGGYIEVISVKVQDALADAATHAAETL 1246
Query: 209 AGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGG 268
++T+R F E+ +FSK+ + + K L++ I+ GI+ I LSV +++ YG
Sbjct: 1247 FNMKTVRWFSAEEREVAKFSKLISVSYKIALKMTIWNGIYSSTSGIFEQLSVFILLWYGS 1306
Query: 269 YLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD-ENVEDY 327
L G ++ +++AF + G + V S+Y + +S + R +EI+ +++
Sbjct: 1307 SLVSNGDLTPSMLIAFNLFLPFITGAVTQVASLYTTYKSYKGSSYRFFEIMQRVPDIQGE 1366
Query: 328 EGISVEKLKGEIEFRNVWFEYEKG--RPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLI 385
GI+ K++G+I+F V F Y + VL+ +++ P + A++G +G GK+T+ +LI
Sbjct: 1367 GGITRTKVRGDIQFNKVSFAYSSNPDQLVLEKIDIKFEPGTITALIGPSGGGKSTMLSLI 1426
Query: 386 MRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDV 445
R Y+ G I DG + K + +L + I V QE LF G+I ENI+ P A ++
Sbjct: 1427 GRLYNIDGGSITLDGTNIKDFNVPNLHEHISIVNQEPSLFSGSIAENIMFGKPTATRSEI 1486
Query: 446 IRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSS 505
I CK+ HDFI +P+GY+T GE G LS G++Q I++AR ++K+P +++LDE S
Sbjct: 1487 IEACKQANAHDFITAMPEGYDTLIGERGTALSGGQKQRIAIARTIIKNPTVLLLDETTSE 1546
Query: 506 VDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKG 565
+D ++E+LVQ+++ KL+ GRT II+AHRL+ AD + VV D I E G+P ELL++KG
Sbjct: 1547 LDVESEKLVQDSIDKLVVGRTVIIVAHRLTTILTADIIAVVSDSTISEMGTPEELLAKKG 1606
Query: 566 YFY 568
FY
Sbjct: 1607 MFY 1609
>sp|Q03727|COMA_STRPN TRANSPORT ATP-BINDING PROTEIN COMA >gi|520738|gb|AAA69510.1|
(M36180) comA protein [Streptococcus pneumoniae]
Length = 717
Score = 302 bits (764), Expect = 1e-80
Identities = 181/569 (31%), Positives = 314/569 (54%), Gaps = 10/569 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L FI + +R +A +V++ + + N+ Y L+ ID Y+ LG I++ +
Sbjct: 154 LLSFIPILVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLV 213
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
+ + Q + Q + V GQ++ ++ + + + FF T+ TG++VSR D
Sbjct: 214 IVYILQQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRF-TDA 272
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
N + D L S +L + ++ I + + + L +TL ++P+ +I F +
Sbjct: 273 NSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKM 332
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
R+T + A +SS + E + GIETI++ E ++ K + +K +
Sbjct: 333 NRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK 392
Query: 250 PLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSAL 309
L +A LL + ++ G L G +S+G ++ + F P+ N++++ LQ+A
Sbjct: 393 ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQ 452
Query: 310 AALERIYEIL----DDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPA 365
A R+ E+ + E + E +S+ +KG++ F+ V ++Y GR VL D+NL +P
Sbjct: 453 VANNRLNEVYLVASEFEEKKTVEDLSL--MKGDMTFKQVHYKYGYGRDVLSDINLTVPQG 510
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
SKVA VG +G+GKTT+A +++ FYDP++GEI G++ +I +K+LR+ I Y+PQ+ Y+F
Sbjct: 511 SKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQPYVF 570
Query: 426 PGTIMENILMANPE-AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLI 484
GTI+EN+L+ E +ED++R + I + I ++P Y+T G +S G+RQ I
Sbjct: 571 NGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRI 630
Query: 485 SLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVI 544
+LARA+L D ++ILDEA SS+D TE+ + + +I L +T I IAHRL+I +KV+
Sbjct: 631 ALARALLTDAPVLILDEATSSLDILTEKRIVDNLIAL--DKTLIFIAHRLTIAERTEKVV 688
Query: 545 VVDDGRIVEEGSPGELLSRKGYFYKLYTS 573
V+D G+IVEEG +LL++ G++ L S
Sbjct: 689 VLDQGKIVEEGKHADLLAQGGFYAHLVNS 717
>pir||A39203 comA protein - Streptococcus pneumoniae
Length = 717
Score = 300 bits (761), Expect = 2e-80
Identities = 181/569 (31%), Positives = 313/569 (54%), Gaps = 10/569 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L FI + +R +A +V++ + + N+ Y L+ ID Y+ LG I++ +
Sbjct: 154 LLSFIPILVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLV 213
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
+ + Q + Q + V GQ + ++ + + + FF T+ TG++VSR D
Sbjct: 214 IVYILQQILSYAQEYLLLVLGQPLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRF-TDA 272
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
N + D L S +L + ++ I + + + L +TL ++P+ +I F +
Sbjct: 273 NSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKM 332
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
R+T + A +SS + E + GIETI++ E ++ K + +K +
Sbjct: 333 NRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK 392
Query: 250 PLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSAL 309
L +A LL + ++ G L G +S+G ++ + F P+ N++++ LQ+A
Sbjct: 393 ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQ 452
Query: 310 AALERIYEIL----DDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPA 365
A R+ E+ + E + E +S+ +KG++ F+ V ++Y GR VL D+NL +P
Sbjct: 453 VANNRLNEVYLVASEFEEKKTVEDLSL--MKGDMTFKQVHYKYGYGRDVLSDINLTVPQG 510
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
SKVA VG +G+GKTT+A +++ FYDP++GEI G++ +I +K+LR+ I Y+PQ+ Y+F
Sbjct: 511 SKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQPYVF 570
Query: 426 PGTIMENILMANPE-AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLI 484
GTI+EN+L+ E +ED++R + I + I ++P Y+T G +S G+RQ I
Sbjct: 571 NGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRI 630
Query: 485 SLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVI 544
+LARA+L D ++ILDEA SS+D TE+ + + +I L +T I IAHRL+I +KV+
Sbjct: 631 ALARALLTDAPVLILDEATSSLDILTEKRIVDNLIAL--DKTLIFIAHRLTIAERTEKVV 688
Query: 545 VVDDGRIVEEGSPGELLSRKGYFYKLYTS 573
V+D G+IVEEG +LL++ G++ L S
Sbjct: 689 VLDQGKIVEEGKHADLLAQGGFYAHLVNS 717
>pir||A75282 ABC transporter, ATP-binding protein, MsbA family - Deinococcus
radiodurans (strain R1)
>gi|6460192|gb|AAF11923.1|AE002068_6 (AE002068) ABC
transporter, ATP-binding protein, MsbA family
[Deinococcus radiodurans]
Length = 588
Score = 300 bits (759), Expect = 4e-80
Identities = 180/539 (33%), Positives = 300/539 (55%), Gaps = 12/539 (2%)
Query: 39 LASPYILRVAIDHYIIPGR-YKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNL 97
L + YI R + + P + + EL + L + L Q + + + G + R++
Sbjct: 49 LCAGYITRTVLT--LTPQQAWPELLRVGGLMVGLLAVQVAANSFLDYQGHMMGTFIERDM 106
Query: 98 RSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAM 157
R L + + F+ T TG L+SR+ D + ++ G +++S G+ V +
Sbjct: 107 RRDLFAHLQKLPFGFYDTHRTGQLMSRVTGDLYDIGELAHHGPEDLFIALVSFVGVFVIL 166
Query: 158 LLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAF 217
L++ LTL+ L +P M ALYF ++ RA ++RQ+I ++++ VE+S+AGI +++F
Sbjct: 167 AGLNLPLTLILLAFLPFMAAYALYFNVQLNRALLQSRQRIGEVNAQVEDSLAGIRVVQSF 226
Query: 218 GKEKDVEKEFSKVS---TETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKG 274
E + F + E + R +Y F+ M + L I V+ +GG+ +G
Sbjct: 227 TGEGTEARRFGAANDLFVEGRRGEYRAELY---FYQGMTAFTGLMTIAVLMFGGWAILQG 283
Query: 275 AVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD-DENVEDYEGIS-V 332
+ I +V ++ PI +V++ LQ + +R E++ ++ D G + +
Sbjct: 284 GLRIDGLVTYLMCVGILLEPIRRLVNLARVLQEGVTGFQRFREMMAVTPDIVDAPGAAEL 343
Query: 333 EKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDP 391
+ ++GE+EF+ V F Y P VL+D+NL I VA+VG +G GK+T+ LI RFYD
Sbjct: 344 QNVRGEVEFQGVSFGYSPDAPPVLRDLNLKIRAGEFVALVGASGVGKSTLCALIPRFYDV 403
Query: 392 TKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKE 451
+ G++L DG D ++ SLR+ +G V Q+ YLF GT+MENI P A E + + ++
Sbjct: 404 SAGQVLVDGHDVCGVTLASLRRSVGVVQQDVYLFSGTVMENIRYGRPGATEAEAMDAARQ 463
Query: 452 LGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTE 511
G HDFI +LP+GY T G+ G LS G++Q +S+AR LKDP I+I DEA SS+D ++E
Sbjct: 464 AGAHDFITRLPQGYHTDIGQRGVKLSGGQKQRLSIARVFLKDPPILIFDEATSSLDNESE 523
Query: 512 QLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
+LVQ ++ +L RT+++IAHRLS R A +++V+ + + EEGS ELL+ G + +L
Sbjct: 524 RLVQESLERLARRRTTLVIAHRLSTVRNAHRIVVLTENGVAEEGSHAELLALGGEYARL 582
>pir||A75554 ABC transporter, ATP-binding protein, MsbA family - Deinococcus
radiodurans (strain R1)
>gi|6457828|gb|AAF09749.1|AE001878_8 (AE001878) ABC
transporter, ATP-binding protein, MsbA family
[Deinococcus radiodurans]
Length = 606
Score = 300 bits (759), Expect = 4e-80
Identities = 175/583 (30%), Positives = 311/583 (53%), Gaps = 13/583 (2%)
Query: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE 60
M+ + S+ +R R + ++ ++GS A L P + +D I +
Sbjct: 1 MSQPAQPSVTRRLYGLLTPYRTAVGAGLLLLLGSVAAELYPPLVWIRVVDQGIPARDWGL 60
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
+G + + Q + + E GQ+ +LR+ ++ K+ + D+F+T+ TGD
Sbjct: 61 IGGQLAVLVGVFALQQVLSAWRGVLLERAGQQFTLDLRTAVYRKLQSQSADYFETQRTGD 120
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L+ R+ D + + DVLV G + + L L G+I + L L ++T + + ++
Sbjct: 121 LLVRVTGDVDALQDVLVRGTDSVIANALRLVGVIGIFIALQPLLGVLTTLPMLAVGLLLW 180
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+G +R AYR R ++ ++S+++ + +AGI ++ F +E+ + E + R
Sbjct: 181 NYGKTVRPAYRAARARLGELSALIADRLAGIRVVQGFAREEAEAARVEALGRELYREQAR 240
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
+P+ L ++++ G +L G ++G ++A+ Y + F GPI+++V+
Sbjct: 241 AVALRNRAFPVARFVGNLGNVIMLGGGAWLILAGQFTLGGLLAYRGYGRYFYGPIDDLVN 300
Query: 301 MYDSLQSALAALERIYEILDDE-NVED--YEGISVEKLKGEIEFRNVWFEYEKG------ 351
+ D LQ A AA R++ +LD V D + ++GE+ F NV F Y+
Sbjct: 301 ISDLLQRAEAAGRRVFAVLDAPVTVADPAHPKPLPTPVRGELHFDNVTFGYDSASYDSAS 360
Query: 352 ----RPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKIS 407
+P+L+ V L+IP +VA++G +GAGK+T+ L+ R +DP G +L DG+D + ++
Sbjct: 361 SDPTQPILRGVTLHIPAGQRVALLGASGAGKSTLLGLVTRQHDPQSGRVLLDGVDVRDVA 420
Query: 408 RKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYET 467
LR +PQ+T+LF T++EN+ A P+A +V + DF+ LP+G ET
Sbjct: 421 LAELRTAAAVMPQDTFLFHDTVLENVRYARPDAALAEVEEALRAAYALDFVRALPQGLET 480
Query: 468 SAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTS 527
GE G LS G+RQ +++AR +L P +++LDE S+VD ++E V A+ LM+GRTS
Sbjct: 481 LVGERGVRLSGGQRQRLAIARTLLARPALLLLDEPTSAVDAESEAQVVAALNDLMQGRTS 540
Query: 528 IIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
+ + HRLS+ R AD+V+V+D G +VE+G P L +R G + +L
Sbjct: 541 LTVTHRLSLARAADRVLVLDGGVVVEDGPPALLRTRGGPYARL 583
>pir||G70837 probable ABC transporter Rv0194 - Mycobacterium tuberculosis (strain
H37RV) >gi|2909592|emb|CAA17316.1| (AL021928)
hypothetical protein Rv0194 [Mycobacterium tuberculosis]
Length = 1194
Score = 298 bits (754), Expect = 1e-79
Identities = 173/565 (30%), Positives = 290/565 (50%), Gaps = 4/565 (0%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L+R ++E R LA+ ++ + A L P ++R ID I L + A+
Sbjct: 616 LRRLLREF---RGPLALSLLLVAVQTCAGLLPPLLIRHGIDVGIRRHVLSALWWAALAGT 672
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
++V +W G++VL LRS + + LD F+ +V+ + D
Sbjct: 673 ATVVIRWVVQWGSAMVAGYTGEQVLFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADV 732
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
+ L +GL+ + S+++L GI+VA+L + +L L+ T++P++ + F
Sbjct: 733 EAIVAFLRTGLVVAVISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWT 792
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
YR R ++ +++ + E AG+ +AF E + + S + + +R + +++
Sbjct: 793 YRRARHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYY 852
Query: 250 PLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSAL 309
P + + L+ +V+ G G +S+G +V ++ Y + PI + M+D Q A
Sbjct: 853 PFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFDDYQRAA 912
Query: 310 AALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGR-PVLKDVNLYIPPASKV 368
A RI +L V L+GE+ F V + Y P L +NL IP V
Sbjct: 913 VAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTV 972
Query: 369 AIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGT 428
VG TG+GK+T+ L+ RFYDPT G + DG D ++ R R+G V QE Y+F GT
Sbjct: 973 VFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGT 1032
Query: 429 IMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLAR 488
+ + I P+A + V R +E+G H I L GY G+ LS G+ QL++LAR
Sbjct: 1033 VRDAIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLALAR 1092
Query: 489 AMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDD 548
A L DPDI++LDEA ++DP TE +VQ A + L RT++I+AH L+I AD+++V++
Sbjct: 1093 ARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADRIVVLEH 1152
Query: 549 GRIVEEGSPGELLSRKGYFYKLYTS 573
G +VE+G+ ELL+ G++ +L+ +
Sbjct: 1153 GTVVEDGAHTELLAAGGHYSRLWAA 1177
Score = 249 bits (628), Expect = 9e-65
Identities = 164/536 (30%), Positives = 278/536 (51%), Gaps = 6/536 (1%)
Query: 30 SIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVF 89
++ G+ +A L P + + ID I ++ L A++ + + A + ++ +Y
Sbjct: 27 ALAGTVIAVLV-PLVTKRVIDD-AIAADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRI 84
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILS 149
V +LR + +L+ + S+G L+ R ND +V +L + L +L+
Sbjct: 85 AHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFD-VPNVLRHVLT 143
Query: 150 LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVA 209
L + M L V L L+ + VP++ +IA + A ++ A ++ VV+ +V
Sbjct: 144 LLLGVAVMTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDAAVC 203
Query: 210 GIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGY 269
GI ++AFG+E+ + S A LRVA F PL+ L + V A GG+
Sbjct: 204 GIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLPALGQMAVFALGGW 263
Query: 270 LAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDEN--VEDY 327
+A +G++++G VAF P ++ M Q A A R+ E++D V+
Sbjct: 264 MAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGT 323
Query: 328 EGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMR 387
+ +S E + +EF+ V F Y RPVL++++L + +A+VG G+GK+T+A+L R
Sbjct: 324 KPLSPEA-RLSLEFQRVSFGYVADRPVLREISLSVRAGETLAVVGAPGSGKSTLASLATR 382
Query: 388 FYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIR 447
YD T+G + G D ++++ SLR IG VP++ LF GTI NI P+A E +
Sbjct: 383 CYDVTQGAVRIGGQDVRELTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIAT 442
Query: 448 VCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVD 507
+ I +F+ LP GY+T+ G G LS G+RQ I+LARA+L P ++I+D+ S+VD
Sbjct: 443 AARAAHIEEFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVD 502
Query: 508 PKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR 563
E +Q + + + RT++I R S+ AD+V V+D GR+++ G+P E+ R
Sbjct: 503 AVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVGTPDEVWER 558
>pir||S77337 ABC-type transport protein sll1725 - Synechocystis sp. (strain PCC
6803) >gi|1652519|dbj|BAA17440.1| (D90906) ABC
transporter [Synechocystis sp.]
Length = 610
Score = 296 bits (750), Expect = 4e-79
Identities = 176/584 (30%), Positives = 312/584 (53%), Gaps = 17/584 (2%)
Query: 8 SLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE------- 60
+++ F + ++ R L + +V+++ L P+ L++ ID +IP + +
Sbjct: 16 AVITTFWPQIRAQWRLLLVAMVTLLADVGLRLLEPWPLKLLIDGVLIPTQTQPSLSLWGF 75
Query: 61 --------LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDF 112
L IA+ ++ V++ T T + G +V+ +R QL+ + + +L +
Sbjct: 76 TNLNAAWLLMLIAVGVIIIAVSRAIATYWNTVSLAIVGSRVMAQVRDQLYGHLQRLSLRY 135
Query: 113 FKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSV 172
+GDL+ R+ +D N + ++L++ L + S+L+L G++ M LD+KLTL++L +
Sbjct: 136 HYQARSGDLIIRVSSDANRLQEILLTAALPLVVSLLTLGGMVGVMAWLDLKLTLLSLATF 195
Query: 173 PLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVST 232
PL + A K+R A R + ++S ES++ I+ ++A E+ FS+ +
Sbjct: 196 PLFWLAANRLSAKIRHASLTQRHQEGAVASTAAESLSAIKLVQALSLEQAFADLFSRQNQ 255
Query: 233 ETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFR 292
+++ + L+++ +V+ YGG+L + A++ G V+ F+ Y +
Sbjct: 256 RSLQENIETKRLAANLERLVDVLIAFGTALVMGYGGHLVIEDALTAGTVLVFLTYLRNAY 315
Query: 293 GPINNVVSMYDSLQSALAALERIYEIL-DDENVEDYEG-ISVEKLKGEIEFRNVWFEYEK 350
P+ N L A A+ ERI IL + +++D G I +G IEF+ V F Y
Sbjct: 316 KPVQNFAKYTGRLAKAAASGERILNILAETPDIQDKPGAIPAPFFQGRIEFKYVSFGYHP 375
Query: 351 GRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
+ +L +NL + P K+A+VG +G+GK+T+ +L++R YDPT G+I DG D + S
Sbjct: 376 DQAILDGLNLTVRPGEKIALVGASGSGKSTLLSLLLRLYDPTAGKIFIDGHDLRDYQLTS 435
Query: 411 LRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAG 470
LR ++ V QE+ LF TI ENI A ++ + H FI++LP+GY+T G
Sbjct: 436 LRNQMAVVLQESLLFAATIRENIAYGIEGATMAEIEAAARLANAHKFILELPQGYDTVVG 495
Query: 471 EAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
E G LS G+RQ +++ARA ++ I+ILDE S +D EQLV A+ +L E RT+ ++
Sbjct: 496 ERGTTLSGGQRQRLAIARAAMRQTPILILDEPTSGLDKVNEQLVFEALERLAENRTTFLV 555
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
H L + AD+++ + G+I E+G+ ELL+R+G + L+ Q
Sbjct: 556 THNLQLAIAADQILYLYQGQIREQGTHAELLARQGVYADLFQRQ 599
>dbj|BAA92038.1| (AK002018) unnamed protein product [Homo sapiens]
Length = 735
Score = 295 bits (748), Expect = 7e-79
Identities = 182/568 (32%), Positives = 305/568 (53%), Gaps = 12/568 (2%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS--LVAQWFFTTL 81
L + VV +G+AL N+ P +L ++ R F+ LS L+ + L
Sbjct: 148 LGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGL 207
Query: 82 QTFYTEVF----GQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLV 137
TF V G+++ ++R L +L+ ++ FF TG LVSR+ D
Sbjct: 208 LTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFK 267
Query: 138 SGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKI 197
+ GL S +AG +V++ +L +LTL+ + + P ++ + G +R+ R+ +++I
Sbjct: 268 LVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQI 327
Query: 198 AKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASL 257
A+ V +E++ + T+RAF E+ E+ + + + +F L NIA
Sbjct: 328 ARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACHCRAEELGRGIALFQGLSNIAFN 387
Query: 258 LSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYE 317
V+ + GG L ++ G +++F+ +Q + + N+ ++ + L+A R++E
Sbjct: 388 CMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFE 447
Query: 318 ILDDENVEDYEG---ISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVG 372
+ G + E+L+G + F+NV F Y G VLKD L +PP VA+VG
Sbjct: 448 YMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVG 507
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI-GYVPQETYLFPGTIME 431
++G GKTT+A+L+ RFYDPT G ++ DG D + + LR ++ G++ QE LF TIME
Sbjct: 508 QSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIME 567
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI EA +E+V +E H+FI P+GY T GE G LS G++Q +++ARA++
Sbjct: 568 NIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALI 627
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
K P ++ILDEA S++D ++E++VQ A+ + GRT ++IAHRLS R A ++V+ DGR+
Sbjct: 628 KQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRV 687
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQEVP 579
E G+ ELL + G + +L Q + P
Sbjct: 688 WEAGTHEELLKKGGLYAELIRRQALDAP 715
>gb|AAG18746.1| (AE004979) ABC transport protein; Trp1 [Halobacterium sp. NRC-1]
Length = 642
Score = 294 bits (744), Expect = 2e-78
Identities = 179/580 (30%), Positives = 308/580 (52%), Gaps = 30/580 (5%)
Query: 26 IVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIA-----------MLYLLSLVA 74
+ V++ V + + +LA P +L +AID +I G L F+ +L++ L+A
Sbjct: 42 VAVLASVFARVLDLAPPVLLGLAIDS-VIQGNKAFLPFLPQSVVPSSKPDRLLFMGGLIA 100
Query: 75 QWF-----FTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
F F ++ + F Q + +R+ ++K+ + N+DFF TK TG+++S + ND
Sbjct: 101 GSFLLGAAFHWIRNWGFNSFSQHIQHRVRTDTYDKMQRLNMDFFATKQTGEMMSILSNDV 160
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
N + L GL + + I V + +++ +L ++T+ VP++ + F ++
Sbjct: 161 NRLERFLNDGLNSAFRLSVMVLAIGVYLFVVNWQLAVLTMLPVPIIALFTYRFVNAIQPK 220
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
Y + R + ++S +E ++ GI+ I+ E+ VS A F+
Sbjct: 221 YADVRSSVGHLNSRLENNLGGIQVIKTSNTERYESDRVDDVSQGYFDANWGAITIRIKFF 280
Query: 250 PLMNIASLLSVIVVIAYGGY-------LAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
P + I S + ++ GG + + G + G V FI +Q+F P+ +
Sbjct: 281 PALRIISGVGFVLTFVIGGIWVATGPPMFFSGTLDPGEFVTFILLSQQFIWPMAQFGQII 340
Query: 303 DSLQSALAALERIYEILDD----ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDV 358
+ Q A A+ ERI+ ++++ E D + + V+ G + + +V F Y+ +++ +
Sbjct: 341 NMYQRARASSERIFGLMNEPSRIEENPDADELVVDD--GGVVYDDVRFGYDDDDAIVEHI 398
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+ + +A+VG TGAGK+T+ L++R YD G + DG D ++ SLR+ +GYV
Sbjct: 399 DFQVDGGDTLALVGPTGAGKSTVLKLLLRMYDVDAGAVRVDGQDISGVTLPSLRRHVGYV 458
Query: 419 PQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
Q+T+LF GT+ ENI +A E V+ K H+FI LP GY+T GE G LS
Sbjct: 459 SQDTFLFYGTVEENITYGTFDADREAVVDAAKAAEAHEFIQNLPDGYDTEVGERGVKLSG 518
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQ I +ARA+LKDP+I++LDEA S VD +TE L+Q ++ +L E RT+ IAHRLS +
Sbjct: 519 GQRQRIDIARAILKDPEILVLDEATSDVDTETEMLIQRSLDRLTEDRTTFSIAHRLSTIK 578
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
AD+++V++DG IVE G+ +LL +G + L+ Q E+
Sbjct: 579 DADQIVVLEDGEIVERGTHADLLGDEGLYANLWGVQAGEI 618
>gi|6005804 ATP-binding cassette, sub-family B, member 8; mitochondrial ABC
protein [Homo sapiens] >gi|4321407|gb|AAD15748.1|
(AF047690) ATP-binding cassette protein M-ABC1 [Homo
sapiens]
Length = 718
Score = 293 bits (742), Expect = 4e-78
Identities = 179/570 (31%), Positives = 300/570 (52%), Gaps = 16/570 (2%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAI--------DHYIIPGRYKELGFIAMLYLLSLVAQ 75
L + VV +G+AL N+ P +L + DH + E ++ L+ Q
Sbjct: 131 LGVAVVLALGAALVNVQIPLLLGQLVKVVAKYTRDH--VGSFMTESQNLSTHLLILYGVQ 188
Query: 76 WFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDV 135
T G+++ ++R L +L+ N+ FF TG LVSR+ D
Sbjct: 189 GLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQNITFFDANKTGQLVSRLTTDVQEFKSS 248
Query: 136 LVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQ 195
+ GL S +AG +V++ +L +LTL+ + + P ++ + G +R+ R+ ++
Sbjct: 249 FKLVISQGLRSCSQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQE 308
Query: 196 KIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIA 255
IA+ V +E++ + T+RA E+ E+ + + + +F L NIA
Sbjct: 309 HIARAMGVADEALGNVRTVRALAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIA 368
Query: 256 SLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERI 315
V+ + GG L ++ G +++F+ +Q + + N+ ++ + L+A R+
Sbjct: 369 FNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARV 428
Query: 316 YEILDDENVEDYEG---ISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAI 370
+E + G + E+L+G + F+NV F Y G VLKD L +PP VA+
Sbjct: 429 FEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVAL 488
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI-GYVPQETYLFPGTI 429
VG++G GKTT+A+L+ RFYDPT G ++ DG D + + LR ++ G++ QE LF TI
Sbjct: 489 VGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTI 548
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
MENI EA +E+V +E H+FI P+GY T GE G LS G++Q +++ARA
Sbjct: 549 MENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARA 608
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++K P ++ILDEA S++D ++E++VQ A+ + GRT ++IAHRLS R A ++V+ DG
Sbjct: 609 LIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADG 668
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQEVP 579
R+ E G+ ELL + G + +L Q + P
Sbjct: 669 RVWEAGTHEELLKKGGLYAELIRRQALDAP 698
>sp|P45861|YWJA_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN IN ACDA 5'REGION
>gi|1075816|pir||S55415 ATP-binding transport protein
ywjA - Bacillus subtilis >gi|853754|emb|CAA89862.1|
(Z49782) ABC transporter [Bacillus subtilis]
>gi|2636260|emb|CAB15751.1| (Z99123) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 575
Score = 293 bits (741), Expect = 5e-78
Identities = 176/582 (30%), Positives = 315/582 (53%), Gaps = 22/582 (3%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGR------YKELG 62
+L++F + + S + L L+ P I+ ID ++PGR +G
Sbjct: 1 MLRQFFSYYKPYKTLFFLDFFSAIAGGLMELSFPLIVNYFIDT-LLPGRDWGLIIATSIG 59
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
A+ Y LS Q+ + T++ + G + ++R L + + + + F+ TG L+
Sbjct: 60 LFAV-YALSSALQY----IVTYWGHMLGINIETDMRKSLFDHLQKLSFKFYDNNKTGTLM 114
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
S++ ND + +V G +++++ G ML ++ +L L+T +P+++ +ALYF
Sbjct: 115 SKLTNDLMYIGEVAHHGPEDLFIAVMTILGAFGVMLFINWQLALLTFIIMPIVIWLALYF 174
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFS----KVSTETIKAY 238
KM +A+ + I S+ VE ++ GI ++AFG E ++ F+ + + +Y
Sbjct: 175 NKKMTKAFTTLNKDIGDFSARVENNIGGIRLVQAFGNEAFEKERFAVNNQRFRVTKLSSY 234
Query: 239 LRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNV 298
+A I + L +L V+ G + +G++S G VAF+ PI+ +
Sbjct: 235 KIMAKNGSISYMLTRFVTLF----VLLCGTWFVIRGSLSYGEFVAFVLLTNVLFRPIDKI 290
Query: 299 VSMYDSLQSALAALERIYEILDDE-NVEDY-EGISVEKLKGEIEFRNVWFEYEKGRPVLK 356
++ + +A + E+++ E +++D + V LKG I +++V F Y+ VL
Sbjct: 291 NAIIEMYPRGIAGFKSYMELMETEPDIQDSPDSKDVSGLKGNIRYKHVSFGYDDHHNVLN 350
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
D+NL I VA VG +GAGK+T+ +L+ RFY+ ++G+I DGI K ++ SLR +IG
Sbjct: 351 DINLSIQAGETVAFVGPSGAGKSTLCSLLPRFYEASEGDITIDGISIKDMTLSSLRGQIG 410
Query: 417 YVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLL 476
V Q+ +LF GT+ ENI A EED+ + K+ + + + +P G +T GE G L
Sbjct: 411 VVQQDVFLFSGTLRENIAYGRLGASEEDIWQAVKQAHLEELVHNMPDGLDTMIGERGVKL 470
Query: 477 SVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSI 536
S G++Q +S+AR LK+P I+ILDEA S++D +TE +Q A+ +L EGRT+++IAHRL+
Sbjct: 471 SGGQKQRLSIARMFLKNPSILILDEATSALDTETEAAIQKALQELSEGRTTLVIAHRLAT 530
Query: 537 TRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
+ AD+++VV + I E+G +L+ G + +L+ +Q ++
Sbjct: 531 IKDADRIVVVTNNGIEEQGRHQDLIEAGGLYSRLHQAQFGQM 572
>gb|AAB88659.1| (U62935) multidrug resistance protein 2 [Aspergillus fumigatus]
>gi|2673957|gb|AAB88660.1| (U62936) multidrug resistance
protein 2 [Aspergillus fumigatus]
Length = 791
Score = 290 bits (734), Expect = 3e-77
Identities = 163/494 (32%), Positives = 277/494 (55%), Gaps = 7/494 (1%)
Query: 88 VFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
+ G++++ LRS+L + + +FF GDL+SR+ +DT +V + L GL +
Sbjct: 252 IVGERIVARLRSKLFRQTFVQDAEFFDANRVGDLISRLSSDTIIVGKSITQNLSDGLRAA 311
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEES 207
+S A M + +KL+ + +P + + A ++G +R R+ ++ + ++ + EE
Sbjct: 312 VSGAAGFGLMAYVSLKLSSILALLLPPIGLGAFFYGRAIRNLSRQIQRNLGTLTKIAEER 371
Query: 208 VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
+ ++T ++F E + ++ + + + ++ F+ A ++++ ++ G
Sbjct: 372 LGNVKTSQSFAGEVLEVRRYNNQVRKIFELGKKESLISATFFSSTGFAGNMTILALLYVG 431
Query: 268 GYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE-NVED 326
G + GA++IG + +F+ Y + + S Y L + A R++E+ D + +
Sbjct: 432 GGMVQSGAITIGELTSFLMYTAYAGSSMFGLSSFYSELMKGVGAASRLFELQDRQPTISP 491
Query: 327 YEGISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANL 384
+G V +G I F NV F Y P+ +D+N IP + VAIVG +G GK+TIA++
Sbjct: 492 TKGEKVASARGPIRFENVTFSYPTRPAVPIFRDLNFEIPQGTNVAIVGPSGGGKSTIASI 551
Query: 385 IMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEED 444
++RFY PT+G +L G D ++ KSLR++IG V QE LF GTI ENI P+AK +
Sbjct: 552 LLRFYSPTEGRVLIGGKDITHMNAKSLRRKIGIVSQEPVLFSGTIAENIAYGKPQAKRSE 611
Query: 445 VIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALS 504
++ ++ FI P G +T G G LS G++Q I++ARA++KDPDI+ILDEA S
Sbjct: 612 IVAAARKANC-QFISDFPDGLDTQVGPRGAQLSGGQKQRIAIARALIKDPDILILDEATS 670
Query: 505 SVDPKTEQLVQNAMIKLMEG-RTSIIIAHRLSITRFADKVIVV-DDGRIVEEGSPGELLS 562
++D ++E LV +A+ L+ G T+I IAHRLS + +D +IV+ DGR+ E+GS EL +
Sbjct: 671 ALDAESETLVNSALTALLRGNNTTISIAHRLSTIKRSDTIIVLGPDGRVAEQGSYEELSA 730
Query: 563 R-KGYFYKLYTSQM 575
R G F KL QM
Sbjct: 731 RPDGAFTKLMEWQM 744
>emb|CAA62898.1| (X91786) ATP-binding cassette transporter A [Staphylococcus aureus]
Length = 575
Score = 289 bits (733), Expect = 4e-77
Identities = 173/558 (31%), Positives = 304/558 (54%), Gaps = 15/558 (2%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAIDHYIIPG-RYKELGFIAMLYLLSLVAQWFFTTLQ 82
+A + +S +GS L+ L P +D + + + + +++++ + + L
Sbjct: 22 VAAITISSLGS-LSGLLVPLFTGRIVDKFSVSHINWNLIALFGGIFVINAL----LSGLG 76
Query: 83 TFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLG 142
+ G+K++ +RS L E I+Q + FF +G L+SR+ +DT V+N+ + L
Sbjct: 77 LYLLSKIGEKIIYAIRSVLWEHIIQLKMPFFDKNESGQLMSRLTDDTKVINEFISQKLPN 136
Query: 143 GLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISS 202
L SI++L G ++ + +LD K+TL+T ++P+ V+I + G M++ T+ +IA S
Sbjct: 137 LLPSIVTLVGSLIMLFILDWKMTLLTFITIPIFVLIMIPLGRIMQKISTSTQSEIANFSG 196
Query: 203 VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIV 262
++ + + ++ E+ K E K L+ A + P+ I LL++ +
Sbjct: 197 LLGRVLTEMRLVKISNTERLELDNAHKNLNEIYKLGLKQAKIAAVVQPISGIVMLLTIAI 256
Query: 263 VIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD- 321
++ +G GA++ G ++A I Y + P+ N+ ++ + A+ A RIYEI+ +
Sbjct: 257 ILGFGALEIATGAITAGTLIAMIFYVIQLSMPLINLSTLVTDYKKAVGASSRIYEIMQEP 316
Query: 322 ----ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAG 377
E +ED E + ++ G + F +V F+Y+ + +L DV+ IP A VG +G+G
Sbjct: 317 IEPTEALEDSENVLID--DGVLSFEHVDFKYDV-KKILDDVSFQIPQGQVSAFVGPSGSG 373
Query: 378 KTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMA- 436
K+TI NLI R Y+ G+I Y I R++IGYV Q + GTI +NIL
Sbjct: 374 KSTIFNLIERMYEIESGDIKYGLESVYDIPLSKWRRKIGYVMQSNSMMSGTIRDNILYGI 433
Query: 437 NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDI 496
N +E++I K HDFIM+ +GY+T GE G LS G+RQ I +AR+ +K+PDI
Sbjct: 434 NRHVSDEELINYAKLANCHDFIMQFDEGYDTLVGERGLKLSGGQRQRIDIARSFVKNPDI 493
Query: 497 VILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGS 556
++LDEA +++D ++E +Q A+ LMEGRT+I+IA+RLS + A ++I +D G++ +G+
Sbjct: 494 LLLDEATANLDSESELKIQEALETLMEGRTTIVIANRLSTIKKAGQIIFLDKGQVTGKGT 553
Query: 557 PGELLSRKGYFYKLYTSQ 574
EL++ + SQ
Sbjct: 554 HSELMASHAKYKNFVVSQ 571
>gb|AAF45509.1| (AE003417) EG:171D11.2 gene product [Drosophila melanogaster]
Length = 643
Score = 289 bits (733), Expect = 4e-77
Identities = 201/605 (33%), Positives = 322/605 (53%), Gaps = 35/605 (5%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHY-----IIPGRY 58
K S R + SE+ L + +V S+ ++ P L ID +
Sbjct: 34 KMGRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSGMDSAAM 93
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKST 118
+LG ++L V F + +++R+LRS+L+ +L + +F TK T
Sbjct: 94 AKLGEYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGT 153
Query: 119 GDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVII 178
G+L++R+ NDT +V L + GL S+ + M+ +L V+ VP M +
Sbjct: 154 GELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGM 213
Query: 179 ALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAY 238
A+ +G +RR + K A+I EE ++T++ F +E+ F E ++
Sbjct: 214 AIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIG 273
Query: 239 LRV----AIYMGIFWP----LMNIASL------------LSVIVVIAYGGYLAYKGAVSI 278
+ AI+ G+ P L I + +I V+ YGG L + +++I
Sbjct: 274 YKETRARAIFFGLVRPKGKVLRKIIKICYPLFQTGFCGNFIIISVLYYGGTLVLQDSLTI 333
Query: 279 GVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE-NVEDYEGI-SVEKLK 336
G + AF+ YA +N + + Y L + A ERI+EILD E ++ +G+ +EK
Sbjct: 334 GALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIPIDKGVVPLEKPV 393
Query: 337 GEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTK 393
GE+ F+NV+F + RP VL D +L + P + A+VG++G+GKTTIA L++R YDP
Sbjct: 394 GEVGFQNVFFTFPT-RPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQG 452
Query: 394 GEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILM-ANP--EAKEEDVIRVCK 450
G + DGID + ++ + LR IG V QE LF +I ENIL ANP E + +V +
Sbjct: 453 GTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIE 512
Query: 451 ELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKT 510
+ + F +LP G +T G+ G +LS G++Q +++ARA++K+P I+ILDEA S++D +
Sbjct: 513 DANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVS 572
Query: 511 EQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLS-RKGYFYK 569
E LVQNA+ L++GRT + IAHRLS R AD++ V+ DG+IVE+GS EL+ ++G F +
Sbjct: 573 ENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRE 632
Query: 570 LYTSQ 574
L SQ
Sbjct: 633 LVASQ 637
>dbj|BAB04876.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 583
Score = 289 bits (733), Expect = 4e-77
Identities = 184/569 (32%), Positives = 319/569 (55%), Gaps = 15/569 (2%)
Query: 7 LSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAM 66
L L F KE +R T+A+V++ IVG + +LA +IL +AID + + +L +
Sbjct: 5 LGQLSWFFKEEW-KRYTIALVLLLIVG--ITDLAPAWILGLAIDDF----QMGQLSVQSG 57
Query: 67 LY---LLSLVAQWFFTTLQTFYTEVFGQKVL--RNLRSQLHEKILQSNLDFFKTKSTGDL 121
LY +L+L+ + + +++FG + R LRS+ + + + F++ + TGDL
Sbjct: 58 LYYGGILTLIMVISYGLTFVWMSKLFGGAFVIERKLRSKFMRHLFKMDPTFYERQRTGDL 117
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAM-LLLDVKLTLVTLTSVPLMVIIAL 180
++R ND V++ G+L + S + + I++AM +L+D KLT+ + +PLM II
Sbjct: 118 MARGTNDLKAVSNTAGFGILTLIDSSVFMFTILIAMCVLIDWKLTIAAVLPLPLMAIIIT 177
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
G K+ + + ++ V ESV G+ IRAF KE+ E F ++S + +
Sbjct: 178 VLGKKIHGRFMMAQDAFGSLNDKVLESVGGLRVIRAFSKERADEDHFREMSENVYQKNIL 237
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
VA +F P +NI +S I+ + +G YL ++ +++G +V F Y P+ +
Sbjct: 238 VAKTDALFEPAVNIIVGMSYIIGLGFGSYLVFQQQITLGQLVTFNVYLGMLIWPMFAIGE 297
Query: 301 MYDSLQSALAALERIYEILDD-ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPV-LKDV 358
+ + +Q A+L+RI E L + E+V + E + +I F+ + F+Y + LK V
Sbjct: 298 LINIMQRGSASLDRIDETLREREDVPNPEQPTNTTDFQDIRFQQLSFKYPGSKGTQLKQV 357
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+ + + IVG+TG+GKTT+ ++++Y +GE+ + + ++ +RK IGYV
Sbjct: 358 SFQVNRGETLGIVGRTGSGKTTLVKQLLKYYPIHEGEVSLTDTALRDMEKQHVRKWIGYV 417
Query: 419 PQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
PQ+ LF T+ ENIL +A EE++ + + + LP G ET GE G LS
Sbjct: 418 PQDHILFSKTVKENILFGKQDAMEEELQKAIRLSAFDQDLSFLPDGLETLVGEKGVALSG 477
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G++Q IS+ARA++ DPDI+ILD++LS+VD KTE + + K G+T++I HR+S
Sbjct: 478 GQKQRISIARALIADPDILILDDSLSAVDAKTEAKIIGNIRKERAGKTTVITTHRISAVE 537
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYF 567
AD+++V+D+GR++EEG+ +LL + G++
Sbjct: 538 HADRILVLDEGRVIEEGTHQQLLQKDGWY 566
>gi|11425328 ATP-binding cassette, sub-family B, member 10 [Homo sapiens]
Length = 738
Score = 289 bits (733), Expect = 4e-77
Identities = 194/582 (33%), Positives = 317/582 (54%), Gaps = 24/582 (4%)
Query: 11 KRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDH-YIIPG-RYKE------LG 62
++ + A ERR LA V + S++ ++++P+ L ID Y P Y + LG
Sbjct: 158 RKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLG 217
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
A+ +L A ++ + + GQ+++ LR+ L IL+ + FF TG+L+
Sbjct: 218 LSAV-FLCGAAAN----AIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELI 272
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+R+ +DT ++ + L GL + + I M + L L+ VP + IIA+ +
Sbjct: 273 NRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIY 332
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEK-DVEKEFSKVSTETIKAYLRV 241
G +R+ + T+ +A+ + + EE + + T+RAFGKE ++EK SKV ++ +
Sbjct: 333 GRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVD-HVMQLARKE 391
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
A F+ ++ L V+ V+ GG L +++G + +F+ YA I + S
Sbjct: 392 AFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSF 451
Query: 302 YDSLQSALAALERIYEILDDENVEDY-EGISVEK--LKGEIEFRNVWFEYEKGR--PVLK 356
Y L L A R++E+L+ E + EG+ + + +G +EF+NV F Y P+ +
Sbjct: 452 YSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQ 511
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
D +L IP S A+VG +G+GK+T+ +L++R YDP G I DG D ++++ LR +IG
Sbjct: 512 DFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIG 571
Query: 417 YVPQETYLFPGTIMENILMANPEAKE---EDVIRVCKELGIHDFIMKLPKGYETSAGEAG 473
V QE LF +I ENI + E++ RV + FI P+G+ T GE G
Sbjct: 572 TVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKG 631
Query: 474 KLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHR 533
LLS G++Q I++ARA+LK+P I++LDEA S++D + E LVQ A+ +LM+GRT ++IAHR
Sbjct: 632 VLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHR 691
Query: 534 LSITRFADKVIVVDDGRIVEEGSPGELLSR-KGYFYKLYTSQ 574
LS + A+ V V+D G+I E G ELLS+ G + KL Q
Sbjct: 692 LSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQ 733
>pir||T13416 hypothetical protein 171D11.2 - fruit fly (Drosophila melanogaster)
>gi|3766257|emb|CAA15633.1| (AL009147)
/prediction=(method:""genscan"", version:""1.0"",
score:""184.75"")~/prediction=(method:""genefinder"",
version:""084"")~/motif=(desc:""ATP/GTP-binding site
motif A (P-loop)"", dbase:""PROSITE"", acc:""PS00017"",
method:""ppsearch"")~/motif=>
Length = 609
Score = 289 bits (732), Expect = 5e-77
Identities = 184/512 (35%), Positives = 293/512 (56%), Gaps = 30/512 (5%)
Query: 92 KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLA 151
+++R+LRS+L+ +L + +F TK TG+L++R+ NDT +V L + GL S+ +
Sbjct: 93 RIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIG 152
Query: 152 GIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGI 211
M+ +L V+ VP M +A+ +G +RR + K A+I EE +
Sbjct: 153 VGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRRITKVELDKYAEIMKFAEERFGNV 212
Query: 212 ETIRAFGKEKDVEKEFSKVSTETIKAYLRV----AIYMGIFWP----LMNIASL------ 257
+T++ F +E+ F E ++ + AI+ G+ P L I +
Sbjct: 213 KTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGLVRPKGKVLRKIIKICYPLFQ 272
Query: 258 ------LSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+I V+ YGG L + +++IG + AF+ YA +N + + Y L + A
Sbjct: 273 TGFCGNFIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGA 332
Query: 312 LERIYEILDDE-NVEDYEGI-SVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPAS 366
ERI+EILD E ++ +G+ +EK GE+ F+NV+F + RP VL D +L + P +
Sbjct: 333 SERIWEILDRECSIPIDKGVVPLEKPVGEVGFQNVFFTFPT-RPESAVLTDFSLNLMPGT 391
Query: 367 KVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFP 426
A+VG++G+GKTTIA L++R YDP G + DGID + ++ + LR IG V QE LF
Sbjct: 392 TTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFS 451
Query: 427 GTIMENILM-ANP--EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQL 483
+I ENIL ANP E + +V ++ + F +LP G +T G+ G +LS G++Q
Sbjct: 452 CSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQR 511
Query: 484 ISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKV 543
+++ARA++K+P I+ILDEA S++D +E LVQNA+ L++GRT + IAHRLS R AD++
Sbjct: 512 VAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQI 571
Query: 544 IVVDDGRIVEEGSPGELLS-RKGYFYKLYTSQ 574
V+ DG+IVE+GS EL+ ++G F +L SQ
Sbjct: 572 AVLSDGKIVEQGSYNELMGIQEGVFRELVASQ 603
>gi|9961244 ATP-binding cassette, sub-family B, member 10 [Homo sapiens]
>gi|8650412|gb|AAF78198.1|AF216833_1 (AF216833) M-ABC2
protein [Homo sapiens]
Length = 738
Score = 289 bits (731), Expect = 7e-77
Identities = 193/582 (33%), Positives = 318/582 (54%), Gaps = 24/582 (4%)
Query: 11 KRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDH-YIIPG-RYKE------LG 62
++ + A ERR LA V + S++ ++++P+ L ID Y P Y + LG
Sbjct: 158 RKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLG 217
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
A+ +L A ++ + + GQ+++ LR+ L IL+ + FF TG+L+
Sbjct: 218 LSAV-FLCGAAAN----AIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELI 272
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+R+ +DT ++ + L GL + + I M + L L+ VP + IIA+ +
Sbjct: 273 NRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIY 332
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEK-DVEKEFSKVSTETIKAYLRV 241
G +R+ + T+ +A+ + + EE + + T+RAFGKE ++EK SKV ++ +
Sbjct: 333 GRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVD-HVMQLARKE 391
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
A+ F+ ++ L V+ V+ GG L +++G + +F+ YA I + S
Sbjct: 392 AVARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSF 451
Query: 302 YDSLQSALAALERIYEILDDENVEDY-EGISVEK--LKGEIEFRNVWFEYEKGR--PVLK 356
Y L L A R++E+L+ E + EG+ + + +G +EF+NV F Y P+ +
Sbjct: 452 YSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQ 511
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
D +L IP S A+VG +G+GK+T+ +L++R Y+P G I DG D ++++ LR +IG
Sbjct: 512 DFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYNPASGTISLDGHDIRQLNPVWLRSKIG 571
Query: 417 YVPQETYLFPGTIMENILMANPEAKE---EDVIRVCKELGIHDFIMKLPKGYETSAGEAG 473
V QE LF +I ENI + E++ RV + FI P+G+ T GE G
Sbjct: 572 TVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKG 631
Query: 474 KLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHR 533
LLS G++Q I++ARA+LK+P I++LDEA S++D + E LVQ A+ +LM+GRT ++IAHR
Sbjct: 632 VLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHR 691
Query: 534 LSITRFADKVIVVDDGRIVEEGSPGELLSR-KGYFYKLYTSQ 574
LS + A+ V V+D G+I E G ELLS+ G + KL Q
Sbjct: 692 LSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQ 733
>gb|AAG15222.1|AF288462_2 (AF288462) AbcA [Chloroflexus aurantiacus]
Length = 594
Score = 287 bits (728), Expect = 2e-76
Identities = 184/564 (32%), Positives = 307/564 (53%), Gaps = 13/564 (2%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHY----IIPGRYKELGFIAMLYLLSLVAQW 76
RR L ++ + +G++++ LA P +LR+A+D I+P EL + + +
Sbjct: 26 RRLLLGLLAAALGASVSALA-PLVLRLAVDRVANGTIVP---LELIWFGGALIGLAIIDG 81
Query: 77 FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVL 136
Q V ++ +LR+ L +++L F++ TGDL++R+ ND + V L
Sbjct: 82 GLKFAQRMLIAVTSYRIENDLRADLFDRLLSFEQMFYQQHYTGDLMARLTNDLSAVRQFL 141
Query: 137 VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
GL G +IL+ V M L+ L L+ + +PL I+ + GG+MR+ + + +
Sbjct: 142 GPGLNGAATAILTFLAAAVLMFLVQPVLALIVVLLLPLATIVFVAIGGRMRQIFHRVQDQ 201
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
+S+ +E+ AGI T++AF +E+ F+ + LR + G WP M +
Sbjct: 202 FGVLSTRAQENFAGIRTVKAFAQEEAEIAVFTADNERYRDLNLRYVLLSGALWPAMTLCL 261
Query: 257 LLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
L +++ GG + G ++IG +V F Y P+ + M + Q A A+LER+
Sbjct: 262 GLISALILLVGGQMVAAGTLTIGELVQFNAYLALLAFPMIILGWMVNLFQQATASLERLS 321
Query: 317 EILDDEN-VEDYEGISVEKLKGEIEFRNVWFE--YEKGRPVLKDVNLYIPPASKVAIVGK 373
+IL + + + +GEIEFR V + + +L+D++ +P + +AIVG
Sbjct: 322 DILRRQPLITSPATPRLPAGEGEIEFRGVGVRAGHSDQQWLLRDLSFRVPAGTVLAIVGA 381
Query: 374 TGAGKTTIANLIMRFYDP--TKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
TGAGKTT+ NL+ R DP G++L DGID + + +LR+ IGYVPQE++LF + E
Sbjct: 382 TGAGKTTLINLLGRVRDPDVMSGQVLVDGIDIRDLDLAALRRMIGYVPQESFLFSIPLRE 441
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI + + V + + + + +LP G ET GE G LS G++Q +++ARA++
Sbjct: 442 NIGFGVETVDPDRLNYVVEVSRLVNDLDQLPGGMETMVGERGVTLSGGQKQRVAIARALM 501
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
+DP I++LD+ALSSVD T + + M GRT+IIIA R++ R AD++IV+D+G+I
Sbjct: 502 RDPRILVLDDALSSVDTHTAAQILAGLRTEMTGRTTIIIAQRIATVRDADQIIVLDEGQI 561
Query: 552 VEEGSPGELLSRKGYFYKLYTSQM 575
VE GS ELL+R G + +Y ++
Sbjct: 562 VERGSHQELLARNGRYAAMYRREL 585
>sp|P47261|Y015_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG015
>gi|1361881|pir||F64201 transport ATP-binding protein
msbA homolog MG015 - Mycoplasma genitalium
>gi|1045684|gb|AAC71231.1| (U39680) ABC transporter,
ATP-binding protein [Mycoplasma genitalium]
Length = 589
Score = 287 bits (727), Expect = 2e-76
Identities = 157/526 (29%), Positives = 297/526 (55%), Gaps = 12/526 (2%)
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
L +++ ++ + F Q + Q+ LR + + K+ + FF T++ GD
Sbjct: 66 LTIVSVTVFVAYALIFVFNVAQNYVGIKLYQQTCATLRWKAYLKMQSMSTSFFDTQNNGD 125
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L+SR+ ND ++++ + S+ ++ V + LL + L++L+ + ++ +
Sbjct: 126 LMSRLTNDMYNIDNLFTQAGGQAIQSLFNILTTSVLIFLLSPVIALISLSILATLITFSF 185
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
F K + +Y + + + +S +EE + + + ++ + K+F + + IK +R
Sbjct: 186 AFLKKSKTSYSQVQNNLGDMSGYIEEVLTNHKVVHVLKLQEIMIKDFDQYNKSMIKPTVR 245
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVV-------AFIQYAQRFRG 293
Y + S ++ +V I+ + S G+ V ++I ++
Sbjct: 246 GNTYSIFLFSWFGFISNITYLVSISIATAFSVNSIPSFGISVINYSFMLSYIASLRQITL 305
Query: 294 PINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKL---KGEIEFRNVWFEYEK 350
++ + ++++ +Q + + ER++++LD NVE + +++KL KG I F NV F Y K
Sbjct: 306 ALDQIFTLWNLVQLGVVSAERVFKVLD-LNVEK-DTATIDKLPDIKGNIRFENVAFGYNK 363
Query: 351 GRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
+P L +N + VAIVG TGAGK+TI NL+M+FY P +G+I D + +++K+
Sbjct: 364 DKPTLTGINFSVKHGDVVAIVGPTGAGKSTIINLLMKFYKPFEGKIYMDNFEISDVTKKA 423
Query: 411 LRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAG 470
R++I V Q+++LF GTI ENI + +A ++++I CK HDFIM+LPKGY+T
Sbjct: 424 WREKISIVLQDSFLFSGTIKENIRLGRQDATDDEIIAACKTANAHDFIMRLPKGYDTYIS 483
Query: 471 EAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
LSVGERQL+++ARA++++ +++LDEA SSVD +E+L+Q ++ +LM+ +TS II
Sbjct: 484 NKADYLSVGERQLLTIARAVIRNAPVLLLDEATSSVDVHSEKLIQESIGRLMKNKTSFII 543
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQ 576
+HRLSI R A ++V++DG+++E G+ +L+ + G++ +L S ++
Sbjct: 544 SHRLSIIRDATLIMVINDGKVLEMGNHDQLMKQNGFYARLKQSSVR 589
>pir||E82539 ABC transporter ATP-binding protein XF2582 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107799|gb|AAF85379.1|AE004065_4 (AE004065) ABC
transporter ATP-binding protein [Xylella fastidiosa]
Length = 564
Score = 287 bits (727), Expect = 2e-76
Identities = 175/566 (30%), Positives = 306/566 (53%), Gaps = 12/566 (2%)
Query: 21 RRTLAIV---VVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWF 77
RR LA+ ++++ S+ A L P + IDH F +L + ++A
Sbjct: 2 RRHLALFSGWLIALAVSSAATLTLPSAFKQMIDHGFSSEGQINRTFALLLLVAVILAVG- 60
Query: 78 FTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLV 137
T + F + G+K++ +LRS L+ ++ + F + +LVSR+ D+ ++ ++
Sbjct: 61 -TAARLFSVSLLGEKIITDLRSHLYAHLIGLDASFHDRNRSNELVSRLATDSELLRSIIG 119
Query: 138 SGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKI 197
S + S ++ G ++ + + +L ++L +PL+++ + +++A R ++ +I
Sbjct: 120 STMSVATRSTVTAIGSLIMLFITSPRLASLSLVVIPLVILPIVLGAQHLQKAARTSQDRI 179
Query: 198 AKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASL 257
A +S E++ + T++A+ +E F + +++A R I++ + +I +
Sbjct: 180 ADTNSFAAETLRALRTVQAYAREHYERTRFDRTLETSLQA-ARQRIHIQTWVTAASIVLI 238
Query: 258 LSVIVVIAYGG-YLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
S IV + + G + G +S G + F+ YA G I + +++ LQ A + RI+
Sbjct: 239 FSAIVGVLWAGAHDVIAGRMSAGTLGEFVLYALIGGGSIGALAEVWNELQRAAGGMGRIF 298
Query: 317 EILDDEN---VEDYEGISVEKLKGEIEFRNVWFEYEKG--RPVLKDVNLYIPPASKVAIV 371
E+L ++N V + + L+GEI F V F Y + P L D++L+I P +A V
Sbjct: 299 ELLKEKNTLTVPATPALLPQPLRGEIRFERVGFHYPQRPETPALDDIDLHIRPGETIAFV 358
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G +GAGK+T+ +L++RFYDPT G IL DG+D ++ K LR I V Q+ LF + ME
Sbjct: 359 GPSGAGKSTLLSLLLRFYDPTHGRILIDGVDLRQTDPKVLRTHIALVQQQPTLFTASAME 418
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI +A ++ + FI LP+ Y T GE G LS G++Q I++ARA+L
Sbjct: 419 NIRYGRLDATTAEIEIASRSSEADGFIRALPQSYATELGEHGMSLSGGQQQRIAIARALL 478
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
K+ I++LDEA +++D + EQ VQ A+ +LM GRT++IIAHRL AD+++V+D GRI
Sbjct: 479 KEAPILLLDEATNALDAQNEQAVQQALERLMTGRTTLIIAHRLVTILKADRIVVMDQGRI 538
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQE 577
V +G+ EL++ G + KL Q E
Sbjct: 539 VAQGTHSELIAAGGLYAKLARLQFIE 564
>sp|P75094|Y015_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG015 HOMOLOG
(D12_ORF634) >gi|2146673|pir||S73461 transport
ATP-binding protein msbA - Mycoplasma pneumoniae
(strain ATCC 29342) >gi|1673794|gb|AAB95783.1|
(AE000015) transport ATP-binding protein [Mycoplasma
pneumoniae]
Length = 634
Score = 287 bits (726), Expect = 3e-76
Identities = 164/528 (31%), Positives = 298/528 (56%), Gaps = 12/528 (2%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKST 118
+ L + + +++ + + F Q + Q++ LR + + KI + FF T++
Sbjct: 109 ERLTIVCVTVVVAYILIFSFNVAQNYLGLKLYQEICALLRWKAYLKIQSMSTSFFDTQNN 168
Query: 119 GDLVSRIINDTNVVNDVLVSGLLGG--LGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
GDL+SR+ ND +N++ +GG + S+ L + +L + L++LT + ++
Sbjct: 169 GDLMSRLTNDVYNINNLYAQ--VGGQTIQSLFILMTTATILFVLSPVIALISLTVLIALI 226
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVS----T 232
++ F K R AY + + + +S +EE ++ + + ++ + F K +
Sbjct: 227 ALSFLFLKKARAAYAKVQNNLGDMSGYIEEVLSNHKVVHVLKLQEVMIDNFDKYNRPMVN 286
Query: 233 ETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG-GYLAYKG--AVSIGVVVAFIQYAQ 289
TIKA F + NI L S+ + A+ + G A++ ++++I +
Sbjct: 287 PTIKANTYAVFIYSWFGFISNITYLASISIATAFSVNNIPSFGVSAINYSFMLSYIAALR 346
Query: 290 RFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGIS-VEKLKGEIEFRNVWFEY 348
+ P+N + S+++ +Q + + ER+++ILD E+ + I+ + +KG I F V F Y
Sbjct: 347 QTALPLNQIFSLWNLIQLGIVSGERVFKILDLESPQKQATITKLPNIKGNIRFEKVVFGY 406
Query: 349 EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISR 408
+P+L ++ + VAIVG TGAGK+TI NL+M+FY P G+I D + ++S
Sbjct: 407 SADKPILTGIDFSVKHGDIVAIVGPTGAGKSTIINLLMKFYKPFAGKIYMDNFEISEVSE 466
Query: 409 KSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETS 468
+ R++I V Q+ +LF GTI ENI M +A +E++I CK HDFIM+LP+GY T
Sbjct: 467 TAWREKISIVLQDPFLFSGTIKENIRMGRQDATDEEIIEACKVANAHDFIMRLPQGYNTF 526
Query: 469 AGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSI 528
LSVGERQL+++ARA++++ +++LDEA SS+D +E+L+Q ++ +LM+ +TS
Sbjct: 527 ISNKTDYLSVGERQLLTIARAVIRNAPVLLLDEATSSIDVHSEKLIQQSIGRLMKDKTSF 586
Query: 529 IIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQ 576
II+HRLSI R A +IV++DG+++E G+ +L+ + G++ +L S ++
Sbjct: 587 IISHRLSIIRNATLIIVINDGKVLEMGNHEQLMRQNGFYARLKRSAVK 634
>dbj|BAA97990.2| (AB045382) TAPL [Mus musculus]
Length = 762
Score = 287 bits (726), Expect = 3e-76
Identities = 172/580 (29%), Positives = 314/580 (53%), Gaps = 9/580 (1%)
Query: 2 ADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKEL 61
A+++S + L++ + + L ++ +AL PY AID +I +
Sbjct: 162 AEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQF 221
Query: 62 GFIAMLYLLSLVAQWFFTTLQT-FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
++ L + ++ +T VF + +R LR+ L ++ FF TGD
Sbjct: 222 TTAVVVVCLLAIGSSLAAGIRGGIFTLVFARLNIR-LRNCLFRSLVSQETSFFDENRTGD 280
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L+SR+ +DT +V+D++ + L + + + G++V M L +L+LVT P++++++
Sbjct: 281 LISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSN 340
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+G +R +E + +A+ S+ EE+++ ++T+R+F E++ + F + + K +
Sbjct: 341 IYGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRK 400
Query: 241 -VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
A YM W + L+ + ++ YGG+L G +S G ++AFI Y + +V
Sbjct: 401 EAAAYMSYVWG-SGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVG 459
Query: 300 SMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP---VL 355
S+Y L + A E+++E +D + ++G ++ + L+G ++F NV F Y + RP VL
Sbjct: 460 SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTY-RTRPHTQVL 518
Query: 356 KDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI 415
++V+ + P A+VG +G+GK++ N++ FY G +L DG K L + I
Sbjct: 519 QNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLQGGRVLLDGKPIGAYDHKYLHRVI 578
Query: 416 GYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKL 475
V QE LF +I +NI P E V+ ++ H FIM+L GY T GE G
Sbjct: 579 SLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ 638
Query: 476 LSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLS 535
LS G++Q +++ARA++++P ++ILDEA S++D ++E L+Q A+ ++ T +IIAHRLS
Sbjct: 639 LSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHRLS 698
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
A ++V+D GR+V++G+ +LL++ G + KL QM
Sbjct: 699 TVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQM 738
>gi|11560034 TAP-like ABC transporter [Rattus norvegicus]
>gi|6045150|dbj|BAA85306.1| (AB027520) TAP-like ABC
transporter [Rattus norvegicus]
Length = 762
Score = 287 bits (726), Expect = 3e-76
Identities = 172/580 (29%), Positives = 314/580 (53%), Gaps = 9/580 (1%)
Query: 2 ADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKEL 61
A+++S + L++ + + L ++ +AL PY AID +I +
Sbjct: 162 AEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQF 221
Query: 62 GFIAMLYLLSLVAQWFFTTLQT-FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
++ L + ++ +T VF + +R LR+ L ++ FF TGD
Sbjct: 222 TTAVVVVCLLAIGSSLAAGIRGGIFTLVFARLNIR-LRNCLFRSLVSQETSFFDENRTGD 280
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L+SR+ +DT +V+D++ + L + + + G++V M L +L+LVT P++++++
Sbjct: 281 LISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSN 340
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+G +R +E + +A+ S+ EE+++ ++T+R+F E++ + F + + K +
Sbjct: 341 IYGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRK 400
Query: 241 -VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
A YM W + L+ + ++ YGG+L G +S G ++AFI Y + +V
Sbjct: 401 EAAAYMSYVWG-SGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVG 459
Query: 300 SMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP---VL 355
S+Y L + A E+++E +D + ++G ++ + L+G ++F NV F Y + RP VL
Sbjct: 460 SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGRLAPDHLEGRVDFENVTFTY-RTRPHTQVL 518
Query: 356 KDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI 415
++V+ + P A+VG +G+GK++ N++ FY G +L DG K L + I
Sbjct: 519 QNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLQGGRVLLDGEPIGAYDHKYLHRVI 578
Query: 416 GYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKL 475
V QE LF +I +NI P E V+ ++ H FIM+L GY T GE G
Sbjct: 579 SLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ 638
Query: 476 LSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLS 535
LS G++Q +++ARA++++P ++ILDEA S++D ++E L+Q A+ ++ T +IIAHRLS
Sbjct: 639 LSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHRLS 698
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
A ++V+D GR+V++G+ +LL++ G + KL QM
Sbjct: 699 TVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQM 738
>gi|9955966 ATP-binding cassette, sub-family B, member 9, isoform 2 [Homo
sapiens] >gi|9588085|dbj|BAA97989.2| (AB045381) TAPL
[Homo sapiens] >gi|9622987|gb|AAF89993.1|AF216494_1
(AF216494) ATP-binding cassette protein ABCB9 [Homo
sapiens]
Length = 766
Score = 286 bits (725), Expect = 4e-76
Identities = 169/579 (29%), Positives = 314/579 (54%), Gaps = 9/579 (1%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG 62
+++S + L++ + + L ++ +AL PY AID +I +
Sbjct: 167 EQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFS 226
Query: 63 FIAMLYLLSLVAQWFFTTLQT-FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDL 121
++ L + F ++ +T +F + +R LR+ L ++ FF TGDL
Sbjct: 227 TAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIR-LRNCLFRSLVSQETSFFDENRTGDL 285
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALY 181
+SR+ +DT +V+D++ + L + + + G++V M L +L+LVT P++++++
Sbjct: 286 ISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNI 345
Query: 182 FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR- 240
+G +R +E + +A+ S+ EE+++ ++T+R+F E++ + + + + K +
Sbjct: 346 YGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKE 405
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
A YM W + L+ + ++ YGG+L G ++ G ++AFI Y + +V S
Sbjct: 406 AAAYMYYVWG-SGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGS 464
Query: 301 MYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP---VLK 356
+Y L + A E+++E +D + ++G ++ + L+G ++F NV F Y + RP VL+
Sbjct: 465 VYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTY-RTRPHTQVLQ 523
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
+V+ + P A+VG +G+GK++ N++ FY G +L DG K L + I
Sbjct: 524 NVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVIS 583
Query: 417 YVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLL 476
V QE LF +I +NI P E V+ ++ H FIM+L GY T GE G L
Sbjct: 584 LVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQL 643
Query: 477 SVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSI 536
S G++Q +++ARA++++P ++ILDEA S++D ++E L+Q A+ ++ T +IIAHRLS
Sbjct: 644 SGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLST 703
Query: 537 TRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
A ++V+D GR+V++G+ +LL++ G + KL QM
Sbjct: 704 VEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQM 742
>gi|9845230 ATP-binding cassette, sub-family B, member 9 [Mus musculus]
>gi|9622989|gb|AAF89994.1|AF216495_1 (AF216495)
ATP-binding cassette protein ABCB9 [Mus musculus]
Length = 762
Score = 286 bits (725), Expect = 4e-76
Identities = 172/580 (29%), Positives = 314/580 (53%), Gaps = 9/580 (1%)
Query: 2 ADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKEL 61
A+++S + L++ + + L ++ +AL PY AID +I +
Sbjct: 162 AEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQF 221
Query: 62 GFIAMLYLLSLVAQWFFTTLQT-FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
++ L + ++ +T VF + +R LR+ L ++ FF TGD
Sbjct: 222 TTAVVVVCLLAIGSSLAAGIRGGIFTLVFARLNIR-LRNCLFRSLVSQETSFFDENRTGD 280
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L+SR+ +DT +V+D++ + L + + + G++V M L +L+LVT P++++++
Sbjct: 281 LISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSN 340
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+G +R +E + +A+ S+ EE+++ ++T+R+F E++ + F + + K +
Sbjct: 341 IYGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRK 400
Query: 241 -VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
A YM W + L+ + ++ YGG+L G +S G ++AFI Y + +V
Sbjct: 401 EAAAYMSYVWG-SGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVG 459
Query: 300 SMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP---VL 355
S+Y L + A E+++E +D + ++G ++ + L+G ++F NV F Y + RP VL
Sbjct: 460 SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTY-RTRPHTQVL 518
Query: 356 KDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI 415
++V+ + P A+VG +G+GK++ N++ FY G +L DG K L + I
Sbjct: 519 QNVSFSLSPGKVTALVGPSGSGKSSCVNILESFYPLQGGRVLLDGKPIGAYDHKYLHRVI 578
Query: 416 GYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKL 475
V QE LF +I +NI P E V+ ++ H FIM+L GY T GE G
Sbjct: 579 SLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ 638
Query: 476 LSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLS 535
LS G++Q +++ARA++++P ++ILDEA S++D ++E L+Q A+ ++ T +IIAHRLS
Sbjct: 639 LSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHRLS 698
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
A ++V+D GR+V++G+ +LL++ G + KL QM
Sbjct: 699 TVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQM 738
>gb|AAF48177.1| (AE003489) CG1824 gene product [Drosophila melanogaster]
Length = 761
Score = 286 bits (725), Expect = 4e-76
Identities = 179/547 (32%), Positives = 294/547 (53%), Gaps = 11/547 (2%)
Query: 34 SALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKV 93
+ LA A+ Y++ I++ + K + LY+L Q FT + + G+++
Sbjct: 159 NTLARYANTYVMD-PINNSFVKDVSKPASNLLSLYML----QSGFTFMYIYLLSRVGEQM 213
Query: 94 LRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGI 153
+R L +I+ ++ FF TG+LV+R+ D + GL S L G
Sbjct: 214 AAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGG 273
Query: 154 IVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIET 213
+++ ++ + + L SVP +V+ Y G K+R + ++ + + + V EE+++ I T
Sbjct: 274 SISLFMISPHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRT 333
Query: 214 IRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYK 273
+R+ E + F + E + ++ + IF L N V+ + GG+L
Sbjct: 334 VRSSACEYREMQLFEAETNEAARLAQKLGYGIAIFQGLTNFFLNTLVLSTLFMGGHLMST 393
Query: 274 GAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD-DENVEDYEG--I 330
++S G ++AF+ +Q + + + ++ ++A R++E L VE G I
Sbjct: 394 ESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELLRGYII 453
Query: 331 SVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRF 388
E+L GEI F NV F Y + VLKD +L + P VA+VG +G+GK+TIA+L+ RF
Sbjct: 454 PQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERF 513
Query: 389 YDPTKGEILYDGIDGKKISRKSLRKRI-GYVPQETYLFPGTIMENILMANPEAKEEDVIR 447
Y+P+ G I DG IS LR + G++ Q+ LF +I+ENI P+A EEDV
Sbjct: 514 YEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYA 573
Query: 448 VCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVD 507
+ HDF+ LP GY T GE G LS G+RQ I++ARA+LK+P I+ILDEA S++D
Sbjct: 574 AARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALD 633
Query: 508 PKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
+E VQ A+ +++ RT+++IAHRLS R AD ++V+D GR+VE G EL+ ++G +
Sbjct: 634 ATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELMGKRGLY 693
Query: 568 YKLYTSQ 574
++L Q
Sbjct: 694 FELVRQQ 700
>pir||B83022 transport protein MsbA PA4997 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9951282|gb|AAG08382.1|AE004912_8
(AE004912) transport protein MsbA [Pseudomonas
aeruginosa]
Length = 603
Score = 284 bits (720), Expect = 1e-75
Identities = 164/517 (31%), Positives = 289/517 (55%), Gaps = 6/517 (1%)
Query: 65 AMLYLLSLVAQW--FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
A+ L+ L+A W + L F+ ++ +LR L K+L +F T S+G L+
Sbjct: 82 AVPLLIILIAAWQGLGSFLGNFFLAKVSLGLVHDLRVALFNKLLVLPNRYFDTHSSGHLI 141
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
SRI + +V + + L++ + + +L ++ KLTLV L +P++ ++
Sbjct: 142 SRITFNVTMVTGAATDAIKVVIREGLTVVFLFLYLLWMNWKLTLVMLAILPVIAVMVTTA 201
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
K R+ ++ + + ++ V E++ G +R+FG E EK F S LR+
Sbjct: 202 SRKFRKQSKKIQVAMGDVTHVASETIQGYRVVRSFGGEAYEEKRFLDASQSNTDKQLRMT 261
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
++ P++ + +++ +++ L +G S G +VA+I A PI + +
Sbjct: 262 KTGAVYTPMLQLVIYVAMAILMFL--VLWLRGDASAGDLVAYITAAGLLPKPIRQLSEVS 319
Query: 303 DSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYE-KGRPVLKDVNLY 361
++Q +A E I+E LD+ ED + E++ G +E RN+ F Y + VL D++
Sbjct: 320 STVQRGVAGAESIFEQLDEAAEEDQGTVEKERVSGRLEVRNLSFRYPGTDKQVLDDISFI 379
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
P +A+VG++G+GK+T+ANL+ RFY G+IL DG++ + ++LR+ I V Q+
Sbjct: 380 AEPGQMIALVGRSGSGKSTLANLVPRFYQHNDGKILLDGVEVEDYRLRNLRRHIALVTQQ 439
Query: 422 TYLFPGTIMENILMAN-PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
LF ++ NI + A E++ R K +FI LP+G++T GE G LLS G+
Sbjct: 440 VTLFNDSVANNIAYGDLAGAPREEIERAAKAANAKEFIDNLPQGFDTEVGENGVLLSGGQ 499
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
RQ +++ARA+LKD ++ILDEA S++D ++E+ +Q A+ ++M+GRT+++IAHRLS A
Sbjct: 500 RQRLAIARALLKDAPLLILDEATSALDTESERHIQAALDEVMKGRTTLVIAHRLSTIEKA 559
Query: 541 DKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
D ++V+D G+IVE GS ELL++ G++ +L+ + E
Sbjct: 560 DLILVMDQGQIVERGSHAELLAQNGHYARLHAMGLDE 596
>dbj|BAB06055.1| (AP001515) ABC transporter (ATP-binding protein) [Bacillus
halodurans]
Length = 585
Score = 284 bits (720), Expect = 1e-75
Identities = 170/569 (29%), Positives = 306/569 (52%), Gaps = 18/569 (3%)
Query: 20 ERRTLAIVVVSIVGSALANLASPYILRVAIDHYI-----IPGRYKELGFIAMLYLLSLVA 74
E+++ +V + +L L P ++ + +DH +P + +G +A L L+ VA
Sbjct: 14 EKKSYGFGIVMLAIVSLLTLVPPRVVGIIVDHIYEGTLTMPVLLQWIGVLAALALIVYVA 73
Query: 75 QWFFTTLQTFYTEVFGQ--KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
++ + + +FG ++ R LR+QL+ F++ TGDL++ ND +
Sbjct: 74 RYLWRVM------IFGASLRLARLLRNQLYTHFTNMAAPFYQKHRTGDLMAHATNDIRAI 127
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDV--KLTLVTLTSVPLMVIIALYFGGKMRRAY 190
G+L + S L++ G ++ + + + +LTL++L +PLM ++ Y+G + + +
Sbjct: 128 QATAGQGVLTLVDS-LTMGGFVILTMAITISWELTLISLLPMPLMALLTSYYGSLLHKRF 186
Query: 191 RETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWP 250
+ + ++ V+ESV G+ +AFG+E+ + F K S + +K + VA +F P
Sbjct: 187 HHAQAAFSSLNDKVQESVTGVRVTKAFGQEEQDIEAFRKQSDDVVKKNVAVARVDALFDP 246
Query: 251 LMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALA 310
+++ LS + I +G ++IG + +F Y P+ +++ ++ A
Sbjct: 247 TISLIVGLSYFLAIVFGARFVIAEQLTIGQLTSFTIYLGLLIWPMLAFGFLFNIVERGRA 306
Query: 311 ALERIYEILD-DENVEDYEGISVEKLKGEIEFRNVWFEYEKGR-PVLKDVNLYIPPASKV 368
+ R+ ++L + + D G ++ F Y + P L DV + +
Sbjct: 307 SYNRVSQLLQAKQEITDSRARIHVPPTGHVDVAIDQFVYPNQKEPALADVQFELSEGETL 366
Query: 369 AIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGT 428
IVGKTGAGKTT+ L+ R YD +G I+ DG + + +L+ G VPQ+ +LF T
Sbjct: 367 GIVGKTGAGKTTLLRLLQREYDIKQGTIILDGRPIEHYTLDALKAAFGTVPQDHFLFSAT 426
Query: 429 IMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLAR 488
I +NI A P+A ++I+V + IHD I++ +GY+T GE G LS G++Q +S+AR
Sbjct: 427 IADNIAFAKPDATISEIIQVSQLAHIHDDIIQFEQGYDTVVGERGVTLSGGQKQRVSIAR 486
Query: 489 AMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDD 548
A+L +P+I+ILD++LS+VD KTE+ + +++ +G+T+II AHRLS + AD ++V+DD
Sbjct: 487 ALLANPNILILDDSLSAVDAKTEEAILSSLRAERKGKTTIITAHRLSAIKHADHILVMDD 546
Query: 549 GRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
GRIVE G+ L+ G++ +Y Q E
Sbjct: 547 GRIVERGTHETLMEAGGWYRNMYERQQLE 575
>pir||T36183 probable ABC-type transport protein - Streptomyces coelicolor
>gi|4490982|emb|CAB38879.1| (AL035707) putative ABC
transporter [Streptomyces coelicolor A3(2)]
Length = 615
Score = 284 bits (718), Expect = 2e-75
Identities = 170/568 (29%), Positives = 299/568 (51%), Gaps = 18/568 (3%)
Query: 23 TLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQ 82
TL IV V + L L+ P + R + + +G + L + LV ++
Sbjct: 48 TLGIVAVLSLVVTLLTLSQPVLTRDVLADIEAD---RPVGRLVALLIGVLVVVAVLGGVR 104
Query: 83 TFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLG 142
+ + + ++ R +L ++L+ + + + TGD++SR+ DT ++ V+ SGL
Sbjct: 105 DYLLQRAAEGLVLTARRRLVARLLRLPITEYDQRRTGDMLSRVGADTTMLRAVVTSGLFD 164
Query: 143 GLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISS 202
+ +++ + G + M L+D L T + L V+ + ++R A R+ + +I +++S
Sbjct: 165 TVTNVVMVGGSALMMCLIDPTLFAATALGLGLGVLAVVGLSRRVRGASRDAQDRIGEMTS 224
Query: 203 VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIV 262
VE +++ + TIRA G E+ K + + A +R+A + P+ + ++ +V
Sbjct: 225 AVERAISAVRTIRASGAEEREGKAVDGYAQQAYHAGMRIARLQAMINPITSTTIQVAFLV 284
Query: 263 VIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE 322
V+ GG GA+ +G +VAF+ + P+ ++ Y LQS L AL+RI E++D
Sbjct: 285 VLGLGGARVASGAIQVGDMVAFVLFLFMLWFPLGRALTAYSRLQSGLGALQRIEEMVDLP 344
Query: 323 NVEDY---------------EGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASK 367
D E E IEF V F Y G VL+DV+L +P ++
Sbjct: 345 QETDAVAGPLTVRERTRPGTEPADAEPRPPAIEFEGVSFGYGDGETVLRDVSLAVPRGTR 404
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
A+VG +GAGK+T+ +L+ RFYD T G + G D + + R+ LR R+GYV Q + G
Sbjct: 405 TALVGPSGAGKSTLLSLVERFYDVTSGTVRVGGTDVRDLPRRELRGRLGYVEQSAPVLAG 464
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
T+ +N+ +A P+A ++D+ V + + + I + P+G +T GE G LLS GERQ ++LA
Sbjct: 465 TVRDNLSLAAPDATDDDMREVLRSVNLMGVIERAPQGLDTEVGEGGVLLSGGERQRLALA 524
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
R L P I++LDEA S++D + E L++ A+ + RT +++AHRLS +D+++V++
Sbjct: 525 RTFLAAPPIMLLDEATSNLDARNEALMREAIGTVTADRTLLVVAHRLSTVVDSDQIVVLE 584
Query: 548 DGRIVEEGSPGELLSRKGYFYKLYTSQM 575
GR+V G EL + +L + Q+
Sbjct: 585 HGRVVAAGRHEELTGTSPLYRELASHQL 612
>pir||JC4554 ABC-type transporter homolog - Staphylococcus aureus
>gi|881631|gb|AAB50179.1| (U29478) AbcA [Staphylococcus
aureus] >gi|1586530|prf||2204232A ABC transporter-like
protein [Staphylococcus aureus]
Length = 575
Score = 283 bits (716), Expect = 4e-75
Identities = 171/558 (30%), Positives = 300/558 (53%), Gaps = 15/558 (2%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAIDHYIIPG-RYKELGFIAMLYLLSLVAQWFFTTLQ 82
+A + +S +GS L+ L P +D + + + + +++++ + + L
Sbjct: 22 VAAITISSLGS-LSGLLVPLFTGRIVDKFSVSHINWNLIALFGGIFVINAL----LSGLG 76
Query: 83 TFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLG 142
+ G+K++ +RS L E I+Q + FF +G L+SR+ +DT V+N+ + L
Sbjct: 77 LYLLSKIGEKIIYRIRSVLWEHIIQLKMPFFDKNESGQLMSRLTDDTKVINEFISQKLPN 136
Query: 143 GLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISS 202
L SI++L G ++ + +LD K+TL+T ++P+ V+I + G M++ T+ +IA S
Sbjct: 137 LLPSIVTLVGSLIMLFILDWKMTLLTFITIPIFVLIMIPLGRIMQKISTSTQSEIANFSG 196
Query: 203 VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIV 262
++ + + ++ E+ K E K L+ A + P+ I LL++ +
Sbjct: 197 LLGRVLTEMRLVKISNTERLELDNAHKNLNEIYKLGLKQAKIAAVVQPISGIVMLLTIAI 256
Query: 263 VIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD- 321
++ +G GA++ G ++A I Y + P+ N+ ++ + A+ A RIYEI+ +
Sbjct: 257 ILGFGALEIATGAITAGTLIAMIFYVIQLSMPLINLSTLVTDYKKAVGASSRIYEIMQEP 316
Query: 322 ----ENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAG 377
E +ED E + ++ G + F +V F+Y+ + +L DV+ IP A VG +G+G
Sbjct: 317 IEPTEALEDSENVLID--DGVLSFEHVDFKYDV-KKILDDVSFQIPQGQVSAFVGPSGSG 373
Query: 378 KTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMA- 436
K+TI NLI R Y+ G+I Y I R++IGYV Q + GTI +NIL
Sbjct: 374 KSTIFNLIERMYEIESGDIKYGLESVYDIPLSKWRRKIGYVMQSNSMMSGTIRDNILYGI 433
Query: 437 NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDI 496
N +E++I K HDFIM+ +GY+T GE G LS G+RQ I +AR+ +K+PDI
Sbjct: 434 NRHVSDEELINYAKLANCHDFIMQFDEGYDTLVGERGLKLSGGQRQRIDIARSFVKNPDI 493
Query: 497 VILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGS 556
++LDEA +++D ++E +Q A+ LMEGRT+I+I RLS + K+ +D G++ +G+
Sbjct: 494 LLLDEATANLDSESELKIQEALETLMEGRTTIVIRDRLSTLKKPVKLCGLDKGQVTGKGT 553
Query: 557 PGELLSRKGYFYKLYTSQ 574
EL++ + SQ
Sbjct: 554 HSELMASHAKYKNFVVSQ 571
>gb|AAB37564.1| (U40139) ComA [Streptococcus gordonii]
Length = 532
Score = 282 bits (713), Expect = 9e-75
Identities = 172/539 (31%), Positives = 300/539 (54%), Gaps = 16/539 (2%)
Query: 43 YILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLH 102
Y L+ ID Y+ LG I++ ++ + Q F + Q + V GQ++ ++
Sbjct: 2 YYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSIDVILSYI 61
Query: 103 EKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDV 162
+ + Q + FF T+ TG++VSR D N + D L S +L + ++ I + + +
Sbjct: 62 KHVFQLPMSFFATRRTGEIVSRF-TDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNS 120
Query: 163 KLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKD 222
L +TL +P+ +I F + ET + + +SS + E + GIETI++ EK
Sbjct: 121 SLFFLTLLGIPVYALIIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEK- 179
Query: 223 VEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI----ASLLSVIVVIAYGGYLAYKGAVSI 278
+ + K+ E + YL+ + G L + A L+ ++++ G L +S+
Sbjct: 180 --QRYQKIDKEFV-TYLKKSFAYGRSESLQKVLKAAARLILNVLILWLGATLVMDQKISL 236
Query: 279 GVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEI-LDDENVEDYEGIS-VEKLK 336
G ++ + F P+ N++++ LQSA A ER+ E+ L E+ + I + +
Sbjct: 237 GQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVKSEFEEKKLIKDLSHFQ 296
Query: 337 GEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEI 396
+I+FR V ++Y G VL +++L+IP SK + VG +G+GKTT+A +++ FY P +G+I
Sbjct: 297 ADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYAPNQGDI 356
Query: 397 LYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILM-ANPEAKEEDVIRVCKELGIH 455
G++ ++ +++LR+ I Y+PQ+ Y+F GTI+EN+L+ A +ED++R + I
Sbjct: 357 CLGGVNLNQLDKQALRQYINYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIR 416
Query: 456 DFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTE-QLV 514
I ++P Y+T G +S G+RQ I+LARA+L D ++ILDEA SS+D TE +++
Sbjct: 417 SDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDAPVLILDEATSSLDILTEKRII 476
Query: 515 QNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTS 573
N M+ +T I IAHRL+I +++V+V+D GRIVE GS EL+ R+G+++ L S
Sbjct: 477 DNLMVL---DKTIIFIAHRLTIAERSEQVVVLDQGRIVESGSHKELIEREGFYHHLVNS 532
>pir||S72637 hypothetical ABC exporter component A - Thermoanaerobacterium
thermosulfurigenes >gi|1542974|gb|AAB08041.1| (U50951)
AbcA [Thermoanaerobacterium thermosulfurigenes]
Length = 582
Score = 281 bits (712), Expect = 1e-74
Identities = 162/570 (28%), Positives = 315/570 (54%), Gaps = 3/570 (0%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
++R +K L + + + +++V + ++ +PY+ + D I G L I ++
Sbjct: 1 MRRVLKYVLRYKLYVIVPSIAMVLAIALDMFNPYLQEIITDKVFIGGDKSLLWPILWAFI 60
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
+ L+ + +V K+ +++ L + I FF +TG+L+SRI D
Sbjct: 61 AITAVRTVLGYLREYIFDVLSAKISVDIKKDLFDHIQSLPFSFFDNMNTGELMSRIGEDV 120
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
+ V + G+ + +++ + ++ KLTLV+L +P++ +AL F K+ +
Sbjct: 121 DNVWRSVSFGIRLFIENMIYFITASTILFFINWKLTLVSLLGMPIIGYLALQFEKKIGIS 180
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
Y + + +++ +E++AG+ ++AF +EK +F ++ E + + + ++
Sbjct: 181 YGKLSDQGVLMNTAAQENIAGVRLVKAFAREKYEIMKFLSLNNENFELSMEQNRIVAKYF 240
Query: 250 PLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSAL 309
P ++ + S+++++ +GG L K ++SIG +VAF Y P+ + + + + +
Sbjct: 241 PPIDFLTNFSIVILVVFGGMLVIKSSLSIGELVAFSGYIYMLIWPMRMLGFLTNLIAQSD 300
Query: 310 AALERIYEILDD-ENVEDYE-GISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASK 367
A+ ++I I+D +++D E I +++LKG++EF++V+F+Y VLKD+N +
Sbjct: 301 ASAKKIMRIMDIVPSIKDSEDSIRIKELKGDVEFKHVFFKYHDDM-VLKDINFKVSAGQT 359
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
VAI+G TG+GK+++ NLI R+YD G + DG D + ++ LR ++ V Q+T+LF
Sbjct: 360 VAIMGTTGSGKSSLVNLIGRYYDVFDGAVYIDGHDVRSLNLHDLRSQMAVVQQDTFLFSE 419
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
+I EN+ +A E+V + DF+ + Y+T GE G LS G++Q IS+A
Sbjct: 420 SIEENVRFGKEDASFEEVKEALRLACADDFVEEFDDKYDTIVGERGIGLSGGQKQRISIA 479
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
RA+++D I+ILD+A S++D TE + + + + T+ IIAHR+S + AD ++ ++
Sbjct: 480 RALIRDAKILILDDATSALDMDTEFRLLKNLSERRKNATTFIIAHRISAVKNADMILYME 539
Query: 548 DGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
DGRIVE G+ ELL ++G +Y++Y Q ++
Sbjct: 540 DGRIVERGTHDELLEKRGRYYEIYLEQFKD 569
>dbj|BAB04170.1| (AP001508) lantibiotic mersacidin transporter system [Bacillus
halodurans]
Length = 724
Score = 281 bits (712), Expect = 1e-74
Identities = 175/576 (30%), Positives = 309/576 (53%), Gaps = 7/576 (1%)
Query: 8 SLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAML 67
+L K ++ + + + L ++ V L LA+P +++ ID ++P + L +
Sbjct: 149 NLWKPYLTYMVKKPKLLLFIIAVSVTLQLLTLANPLLVQFVIDFILLPENREMLQVFLIG 208
Query: 68 YLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIN 127
+ +Q FF +Q + + R + ++ +L FF+ +S GD++ R
Sbjct: 209 LSCYVFSQAFFVFIQGRALVIMQNHLDREMMTKFFRHLLNLPYHFFQVRSFGDILFRA-G 267
Query: 128 DTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMR 187
V+ D+L + LL G+ I L I+ M L LTL+ + +I + K+
Sbjct: 268 SLRVIRDLLANQLLKGILDIGMLVVILAYMTLFSPLLTLIVFLLATVNGLIIYFSRPKIS 327
Query: 188 RAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGI 247
A ++ K +++ + E++ GI I+ G E + +++ + I AY +
Sbjct: 328 EANQKEIMKQSEVQATQTETMYGIFGIKTAGVEDTMYQKWENRFDKLILAYKNKEYILNN 387
Query: 248 FWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQS 307
++++ ++V+ G + AV++G VVAF +F G +++V +S
Sbjct: 388 VNTATTFLTVIAPLIVLYIGSHQVLAQAVTMGTVVAFYSVTTQFFGLSSSLVHTINSFIL 447
Query: 308 ALAALERIYEILDDENVEDYEGI-SVEKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPA 365
A A L R ++ D + + E ++ L GEI ++V F Y + G+ V+KDV+L + P
Sbjct: 448 ANAYLGRAQDVFDSKEEDIGENRKALHNLHGEITLKDVSFSYSRFGQEVVKDVSLRVAPG 507
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
+KVA+VGK+G+GK+T++ +++ Y+PTKGE+ YDG + +++++LR++IG VPQ+ L
Sbjct: 508 TKVALVGKSGSGKSTLSKIMLGLYEPTKGEVYYDGYNLNDLNKRALRQKIGVVPQDVTLL 567
Query: 426 PGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLIS 485
+I ENI + NP+ ED+I K +H+ IM +P YET E G +S G+RQ I+
Sbjct: 568 NQSIRENIALHNPDTSMEDIIEAAKIAQVHEEIMNMPMNYETLVSEMGHNISGGQRQRIA 627
Query: 486 LARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIV 545
LARA++ P I++LDEA SS+D E + + + T I+IAHRL+ AD +IV
Sbjct: 628 LARALVHKPKILLLDEATSSLDHVNEAKIDQYLSAMK--CTRIVIAHRLTTIMNADLIIV 685
Query: 546 VDDGRIVEEGSPGELLSRKGYFYKLYT--SQMQEVP 579
++DG+I+E G+ ELL++ GY+ Y S+ Q+VP
Sbjct: 686 LEDGKIIETGTHTELLNQSGYYASFYNNYSEEQKVP 721
>emb|CAB88985.1| (AL353864) putative ABC-transport protein. [Streptomyces coelicolor
A3(2)]
Length = 624
Score = 281 bits (712), Expect = 1e-74
Identities = 179/590 (30%), Positives = 301/590 (50%), Gaps = 23/590 (3%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
++R A RR + V+ V +AL +A+P + +D + G + +A+L
Sbjct: 27 MRRIGAFARPHRRRIVRFVLLGVATALLAVATPVLAGKVVDAIVSDGDEGTVVRLALLIA 86
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
L VA+ + G+ ++ +LR+ + + + + + FF TG LVSR+ ND
Sbjct: 87 LIAVAEAVLGIFSRRLSATLGEGLILDLRTAVFDHVQRMPVAFFTRTRTGALVSRLNNDV 146
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
+ L G + ++++L + ML L ++TL+ L +P+ V+ A G +M R
Sbjct: 147 IGAQRAFSNTLSGVVSNVVTLLLTLAVMLTLSWQITLLALVLLPVFVLPARRMGRRMARM 206
Query: 190 YRETRQKIAKISSVVEE--SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGI 247
RE A + + + E S G I+ FG+ ++ EF+ + +R A
Sbjct: 207 QREAAALNAAMGTRMTERFSAPGATLIKLFGRPEEESAEFADRARRVADIGVRTATAQAA 266
Query: 248 FWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQS 307
F + + S L++ +V GG+ A +G + G VVA R P+ + + S
Sbjct: 267 FITALTLVSALALALVYGLGGFFALRGTLDAGAVVALALLLTRLYAPLTALAGARVEVMS 326
Query: 308 ALAALERIYEILDDENVEDYEGISVEKLKGEI--EFRNVWFEYEK--------------- 350
AL + ER++E+LD + D + + G + EF +V F Y
Sbjct: 327 ALVSFERVFEVLDLAPLIDEKPDARPVPDGPVAVEFDDVRFGYPSADKVSLASLEEVATL 386
Query: 351 ----GRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKI 406
G VL ++ P +A+VG +GAGK+TIA L+ R YD G + G+D +++
Sbjct: 387 DTRGGEEVLHGLSFRAEPGQTIALVGSSGAGKSTIAQLLPRLYDTDGGTVRVGGVDVREL 446
Query: 407 SRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYE 466
S +SLR +G V Q+ +LF T+ N+L+A P+A E+D+ + + D + LP G +
Sbjct: 447 SARSLRDTVGMVTQDGHLFHDTVRANLLLARPDATEDDLWEALRRARLADLVRSLPDGLD 506
Query: 467 TSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRT 526
T GE G LS GERQ +++AR +L +VILDEA + +D +E VQ A+ + ++GRT
Sbjct: 507 TVVGERGYRLSGGERQRMTIARLLLARQRVVILDEATAHLDNTSEAAVQEALTEALQGRT 566
Query: 527 SIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQ 576
+++IAHRLS R AD+++VV+ GRIVE G+ ELL+ G + +L+ +Q +
Sbjct: 567 AVVIAHRLSTVRAADRILVVEAGRIVESGTHEELLAVDGRYAQLHRTQFE 616
>pir||I56273 ATP-dependent transport protein SapT - Lactobacillus sake (strain
Lb706) plasmid pLSA60 >gi|599856|emb|CAA86946.1|
(Z46867) ABC exporter [Lactobacillus sakei]
Length = 719
Score = 281 bits (711), Expect = 2e-74
Identities = 180/590 (30%), Positives = 312/590 (52%), Gaps = 44/590 (7%)
Query: 2 ADKSSL-----SLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPG 56
A+K+SL +LLK+ L I ++SI+GS Y L+ ID YI
Sbjct: 150 AEKASLWSFVPTLLKQKFLVIHITLAALLITIISILGS--------YFLQTVIDTYIPNK 201
Query: 57 RYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTK 116
LG + + L+ V Q FT Q F V GQ++ + + + + FF T+
Sbjct: 202 MTSTLGIVTLGLLVFYVFQAIFTYTQNFLLVVLGQRLSIEIILSYLRHVFELPMSFFATR 261
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
TG+++SR ND N + D L S ++ + + + + +++ + L +TL ++PL +
Sbjct: 262 KTGEIISRF-NDANKIIDALASSIISIFLDVTIVVVMGIILMIQNTTLFWITLMAIPLYI 320
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKD------------VE 224
+ F + ++ Q A ++S + E + GIETI+A E + ++
Sbjct: 321 AVITLFVKPFEKLNQKEMQSNAMLNSAIIEDLHGIETIKALSSEHERYQKIDTAFIDYLK 380
Query: 225 KEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAF 284
K F+ V T+T++ +++ I +G+ ++V+ G L +SIG ++ +
Sbjct: 381 KNFNYVKTDTLQQAIKLFIQLGLN------------LIVLWVGAILVTHNELSIGQLMTY 428
Query: 285 IQYAQRFRGPINNVVSMYDSLQSALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFR 342
F P+ N++++ LQSA A R+ E+ +D E E E+L G I+
Sbjct: 429 NALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVFLVDSEFTEKRAIKRAEQLVGPIKIE 488
Query: 343 NVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGID 402
NV + Y G+ VL+ +NL I P K+ IVG +G+GK+T+ L++ F+ P +G++ + +
Sbjct: 489 NVSYCYGYGKNVLEQINLTIHPGEKLTIVGMSGSGKSTLVKLLVDFFQPNEGQVTINQHN 548
Query: 403 GKKISRKSLRKRIGYVPQETYLFPGTIMENILMAN-PEAKEEDVIRVCKELGIHDFIMKL 461
I +K LR+ I Y+PQ+ YLF GTI++N+ + N + D+I+ C+ I I K+
Sbjct: 549 ITNIDKKVLRQTINYIPQDPYLFSGTILDNLKLGNRTNVTQSDLIKACELAEIKQDIEKM 608
Query: 462 PKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTE-QLVQNAMIK 520
P +ET E G LS G++Q +++ARA+L ++I DE+ S +D TE +LV++ M
Sbjct: 609 PLQFETLLDEEGSTLSGGQKQRLTIARALLSPAKVLIFDESTSGLDTITESRLVEHLM-- 666
Query: 521 LMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
+ +T I IAHRLSI + + VIV+++GRI+E GS +L+++K +Y+L
Sbjct: 667 TLTDKTIIFIAHRLSIAKKTNNVIVMENGRIIESGSHDDLIAKKETYYQL 716
>gb|AAB49750.1| (U63741) multidrug resistance protein LmrA [Lactococcus lactis]
Length = 590
Score = 279 bits (707), Expect = 5e-74
Identities = 165/577 (28%), Positives = 305/577 (52%), Gaps = 11/577 (1%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG 62
DK+S+ + I+ A I +V+ + L L P +++ I+ + ++
Sbjct: 17 DKTSIKHFVKLIRAAKPRYLFFVIGIVAGIIGTLIQLQVPKMVQPLINSFGHGVNGGKVA 76
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
+ LY+ S + + +FG+ V++NLR+++ +K++ + +F TG++
Sbjct: 77 LVIALYIGSAAV----SAIAAIVLGIFGESVVKNLRTRVWDKMIHLPVKYFDEVKTGEMS 132
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIA--- 179
SR+ NDT V +++ + + SIL L G I+ ML + +LTL + +VP++++I
Sbjct: 133 SRLANDTTQVKNLIANSIPQAFTSILLLVGSIIFMLQMQWRLTLAMIIAVPIVMLIMFPI 192
Query: 180 LYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYL 239
+ FG K+ +++ +A + ES++ I +++ EK K+ K +
Sbjct: 193 MTFGQKIGWTRQDS---LANFQGIASESLSEIRLVKSSNAEKQASKKAENDVNALYKIGV 249
Query: 240 RVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
+ A++ G+ P+M ++ +L + ++AYG YL G +S+G ++ + Y G + V
Sbjct: 250 KEAVFDGLMSPVMMLSMMLMIFGLLAYGIYLISTGVMSLGTLLGMMMYLMNLIGVVPTVA 309
Query: 300 SMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVN 359
+ + L A + R+ E+LD+E ++G S++ + +V F Y+ +L D++
Sbjct: 310 TFFTELAKASGSTGRLTELLDEEQEVLHQGDSLDLEGKTLSAHHVDFAYDDSEQILHDIS 369
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
P S +A G +G GK+TI +L+ RFY PT GEI G +S ++ R +IG+V
Sbjct: 370 FEAQPNSIIAFAGPSGGGKSTIFSLLERFYQPTAGEITIGGQPIDSVSLENWRSQIGFVS 429
Query: 420 QETYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
Q++ + GTI EN+ +ED+ +V F+ +P T GE G +S
Sbjct: 430 QDSAIMAGTIRENLTYGLEGNFTDEDLWQVLDLAFARSFVENMPDQLNTEVGERGVKISG 489
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQ +++ARA L++P I++LDEA +S+D ++E +VQ A+ LM+GRT+++IAHRLS
Sbjct: 490 GQRQRLAIARAFLRNPKILMLDEATASLDSESESMVQRALDSLMKGRTTLVIAHRLSTIV 549
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
ADK+ ++ G I G EL++ + K + Q+
Sbjct: 550 DADKIYFIEKGEITGSGKHNELVATHPLYAKYVSEQL 586
>emb|CAA64189.1| (X94434) ABC-transporter PlnG [Lactobacillus plantarum]
Length = 716
Score = 279 bits (706), Expect = 6e-74
Identities = 180/569 (31%), Positives = 301/569 (52%), Gaps = 15/569 (2%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI L +RR + +V++ V + ++ Y L+ ID YI + L +A+ ++
Sbjct: 155 FIPSLLKQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFY 214
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
Q FT Q F V GQ++ + + + + FF T+ TG++VSR + + ++
Sbjct: 215 TFQAIFTYAQNFLLAVLGQRLSIEIILGYIRHVFELPMSFFATRRTGEIVSRFTDASKII 274
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLL-DVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
D L S ++ L +S+ I+ A+L++ ++ L +TL S+P+ ++ L F R +
Sbjct: 275 -DALASTIVS-LFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVILAFNKSFERLNQ 332
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG---IF 248
+ + A +SS + E + GIET++A E + + K+ +E + + Y+ +
Sbjct: 333 KEMESNAILSSAIIEDLHGIETVKALNGETE---RYQKIDSEFVDYLRKSLAYLKADTLQ 389
Query: 249 WPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSA 308
L L+ +VV+ G L +S+G ++ + F P+ N++++ LQSA
Sbjct: 390 QALKLFIQLVLEVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSA 449
Query: 309 LAALERIYEI-LDDENVEDYEGISVE-KLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPAS 366
A R+ E+ L E I E +L G+I+ + V + Y G VL DVNL I
Sbjct: 450 KVANNRLNEVYLVASEFEASRPIHNESQLNGDIKLQGVSYRYGYGENVLDDVNLTIRQHD 509
Query: 367 KVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFP 426
KVAIVG +G+GK+T+ L++ FY P G+++ +G + K I + +LR I Y+PQE Y+F
Sbjct: 510 KVAIVGMSGSGKSTLVKLLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINYIPQEPYIFS 569
Query: 427 GTIMENILMANPEA-KEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLIS 485
TI EN+ + N E+D+ + C+ I I K+ Y+T E G LS G+RQ ++
Sbjct: 570 ATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLT 629
Query: 486 LARAMLKDPDIVILDEALSSVDPKTE-QLVQNAMIKLMEGRTSIIIAHRLSITRFADKVI 544
+AR +L ++I DE+ S +D TE QL+ N + M +T I IAHRLSI + + +I
Sbjct: 630 IARRLLSPAQVLIFDESTSGLDAITEKQLIDN--LVAMTDKTIIFIAHRLSIAKRTNHII 687
Query: 545 VVDDGRIVEEGSPGELLSRKGYFYKLYTS 573
V+ DGR+ EEG+ LL+ GY+Y L S
Sbjct: 688 VLHDGRVAEEGTHAALLNEHGYYYDLINS 716
>gi|9506367 ATP-binding cassette, sub-family B, member 12; Abc-mitochondrial
erythroid [Mus musculus]
>gi|8571454|gb|AAF76889.1|AF266284_1 (AF266284) ABC
transporter [Mus musculus]
Length = 715
Score = 279 bits (705), Expect = 8e-74
Identities = 188/573 (32%), Positives = 309/573 (53%), Gaps = 24/573 (4%)
Query: 20 ERRTLAIVVVSIVGSALANLASPYILRVAIDH-YIIPGRYKELGFIAMLYLLSLVAQWFF 78
ER L+ V + S++ +++P+ L ID Y P G+ L L V F
Sbjct: 132 ERGRLSAAVGFLAVSSVITMSAPFFLGRIIDVIYTNPSE----GYGDSLTRLCAVLTCVF 187
Query: 79 TT------LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
++ + + GQ ++ LR+ L IL+ + FF TG+L++R+ +DT ++
Sbjct: 188 LCGAAANGIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALL 247
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L GL + + + M + L L+ VP + ++A+ +G +R+ +
Sbjct: 248 GRSVTENLSDGLRAGAQASVGVGMMFFVSPSLATFVLSVVPPISVLAVIYGRYLRKLSKA 307
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEK-DVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
T+ +A+ + + EE + I TIRAFGKE +VEK +V + ++ + A+ F+
Sbjct: 308 TQDSLAEATQLAEERIGNIRTIRAFGKEMTEVEKYTGRVD-QLLQLAQKEALARAGFFGA 366
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
++ L V+ V+ GG L +++G + +F+ YA I + S Y L L A
Sbjct: 367 AGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGGLSSFYSELMKGLGA 426
Query: 312 LERIYEILDDE-NVEDYEGISVEK--LKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPA 365
R++E+L+ + + EG+ +++ +G +EFRNV F Y RP V +D +L IP
Sbjct: 427 GGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYP-ARPEVSVFQDFSLSIPSG 485
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
S A+VG +G+GK+T+ +L++R YDP G + DG D ++++ LR +IG V QE LF
Sbjct: 486 SVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLF 545
Query: 426 PGTIMENILMANPEAKE---EDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
++ ENI + V R + +FI P+G++T GE G LLS G++Q
Sbjct: 546 SCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVVGEKGILLSGGQKQ 605
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
I++ARA+LK+P I++LDEA S++D + E LVQ A+ +LMEGRT +IIAHRLS + A+
Sbjct: 606 RIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEGRTVLIIAHRLSTIKNANF 665
Query: 543 VIVVDDGRIVEEGSPGELLSR-KGYFYKLYTSQ 574
V V+D G+I E G+ ELL + G + KL Q
Sbjct: 666 VAVLDHGKICEHGTHEELLLKPNGLYRKLMNKQ 698
>pir||T27215 hypothetical protein Y57G11C.1 - Caenorhabditis elegans
>gi|3881178|emb|CAB16503.1| (Z99281) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=227.6,
E-value=5.9e-65, N=1; PF00664 (ABC transporter
transmembrane region.), Score=121.7, E-value=4.5e-33,
N=1 [Caenorhabditis elegans]
Length = 633
Score = 278 bits (704), Expect = 1e-73
Identities = 168/534 (31%), Positives = 281/534 (52%), Gaps = 21/534 (3%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQT---FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT 115
K I LL + Q+ T ++ F+ + + RN+R QL IL + FF
Sbjct: 89 KSFDIIKRACLLLALIQFSEATCKSACYFFMQYAEKLTARNIRIQLFRSILHQEISFFDE 148
Query: 116 KSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLM 175
TG LVSRI +D+ +++ L + + ++ G I M +LTL + P+
Sbjct: 149 NKTGQLVSRITHDSESISNTLPVHIETLVNNLFMFFGSIPIMFCYSWQLTLTSFIEFPIT 208
Query: 176 VIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSK------ 229
+++ Y+G + + + A + VEE ++ I T+R+F E +K ++K
Sbjct: 209 LLMTRYYGLAVEKLSEKENDATAASNETVEEVLSAIRTVRSFAAENFEQKRYTKNTEDWF 268
Query: 230 -VSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYA 288
+ST+T+ + FW LM + ++ YGGYLA G ++ ++ FI Y
Sbjct: 269 KISTKTVT----LGTIYNYFWALMLRSQ---DVIRYLYGGYLALNGRMAPEALLTFIFYH 321
Query: 289 QRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYE-GISVEKLKGEIEFRNVWFE 347
R IN S++ + + ++ +++ + DY+ G +++G+IEF V F
Sbjct: 322 WRLHTAINAFSSLFSGVMKTIGLSRKVIHLINRKPQLDYDFGTETPEIQGKIEFEVVEFA 381
Query: 348 Y--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKK 405
Y K V+ +NL I VA+VG +G GK+T+ +LI +FY P G IL DGI +
Sbjct: 382 YPTRKTVNVINGINLSIESGKTVALVGPSGNGKSTLVSLIQQFYTPQSGRILTDGIPIQN 441
Query: 406 ISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGY 465
I+ + I V QE LF GTI ENIL EE +++ + +H+F+ K+ GY
Sbjct: 442 INHQHYHSNIALVAQEPTLFSGTIRENILFGIENGTEEAMLKAAEMANVHEFVSKMDDGY 501
Query: 466 ETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGR 525
+T GE G +S G++Q I++ARA++++P ++ILDEA S++D ++E +VQ A+ K + R
Sbjct: 502 DTKCGEKGVQMSGGQKQRIAIARALIRNPRVLILDEATSALDSESEGMVQEALNKCAKER 561
Query: 526 TSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELL-SRKGYFYKLYTSQMQEV 578
T I+IAHRLS R A K+ V+++G + E G EL+ ++ G +YKL + Q+ +
Sbjct: 562 TVIVIAHRLSTVRKAQKIAVIENGSVKEMGCHDELMENQDGLYYKLVSKQLGSI 615
>gb|AAB52482.1| (U97407) Contains similarity to Pfam domain: PF00005 (ABC_tran),
Score=419.6, E-value=9.4e-123, N=2 [Caenorhabditis
elegans]
Length = 1289
Score = 278 bits (703), Expect = 1e-73
Identities = 173/526 (32%), Positives = 282/526 (52%), Gaps = 27/526 (5%)
Query: 67 LYLLSLVAQWFFTT-LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRI 125
+Y L L FFT+ +Q E + ++++ LR + IL+ + +F + TG+L +R+
Sbjct: 115 IYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARL 174
Query: 126 INDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDV--------KLTLVTLTSVPLMVI 177
+D V + GLG +L + A L +TLV + PL+V+
Sbjct: 175 TDDLERVRE--------GLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVL 226
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAF-GKEKDVEKEFSKVSTETIK 236
M R ++ A ++ EE+ + I T+ + G ++++++ ++ +
Sbjct: 227 SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQT 286
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYL-----AYKGAVSIGVVVAFIQYAQRF 291
++ YMGI N+ S + YG L + + V A + +
Sbjct: 287 GIVKYC-YMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSL 345
Query: 292 RGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEY--E 349
G + ++ S + + + A + + R+ + EGI V+ +KG+I F++V F Y
Sbjct: 346 GGALPHLAS-FGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSR 404
Query: 350 KGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRK 409
K VLK ++L + K+A+VG +G GK+TI NL+ RFYDPTKG +L DG+D ++++
Sbjct: 405 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 464
Query: 410 SLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSA 469
SLR++IG V QE LF GTI ENI M N A + V+ CK +DFI +LP GY T
Sbjct: 465 SLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRV 524
Query: 470 GEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSII 529
GE G LS G++Q I++ARA++K+P I++LDEA S++D + E+ VQ A+ + GRT+II
Sbjct: 525 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 584
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
+AHRLS R D++ V G IVE GS EL+S++G FY + +Q+
Sbjct: 585 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTQAQV 630
Score = 210 bits (528), Expect = 5e-53
Identities = 151/501 (30%), Positives = 257/501 (51%), Gaps = 26/501 (5%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKT--KSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
G+ + LR + + +L+ ++ F+ TG L +R D V V L L SI
Sbjct: 793 GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTR-LPVVLASI 851
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMR--RAYRETRQKIAKISSVVE 205
+++ G + +L L+ + VPL+V+ YF +MR + R+T Q + + V
Sbjct: 852 VTICGALGIGFYYGWQLALILVVMVPLLVMGG-YFEMQMRFGKQIRDT-QLLEEAGKVAS 909
Query: 206 ESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIA 265
++V I T+ + +++ + + E L+ A G + SL+ + A
Sbjct: 910 QAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQ--SLIFFMYAAA 967
Query: 266 YGGYLAYKGAVSIG------VVVAFIQYAQRFRGP-INNVVSMYDSLQSALAALERIYEI 318
+ Y G++ + + V + +A F G I N S + A A ++ +
Sbjct: 968 F-----YLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYL 1022
Query: 319 LDDENVEDYEGIS--VEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKT 374
++ D S V+ + G I RNV+F Y K VL+ L I VA+VG +
Sbjct: 1023 IEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHS 1082
Query: 375 GAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENIL 434
G GK+TI L+ RFY+ KG I+ DG + + ++ SLR+++ V QE LF TI ENI
Sbjct: 1083 GCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENIC 1142
Query: 435 MA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKD 493
N ++++ K IH+FI+ LP GY+T GE G LS G++Q I++ARA+++
Sbjct: 1143 YGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRS 1202
Query: 494 PDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVE 553
P +++LDEA S++D ++E++VQ A+ +GRT ++IAHRLS + +D + +V +G+IVE
Sbjct: 1203 PSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVE 1262
Query: 554 EGSPGELLSRKGYFYKLYTSQ 574
+G+ EL+ + + K +Q
Sbjct: 1263 KGTHDELIRKSEIYQKFCETQ 1283
>gb|AAD53033.1|AF115536_1 (AF115536) TAP1 protein [Oncorhynchus mykiss]
Length = 739
Score = 277 bits (702), Expect = 2e-73
Identities = 160/487 (32%), Positives = 275/487 (55%), Gaps = 5/487 (1%)
Query: 92 KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLA 151
++ +++ + + +L+ + FF T TGDLVSRI DTN +++ L L + + +
Sbjct: 226 RIHTSIQGLVFQSVLKQEIAFFDTAQTGDLVSRITTDTNDMSESLSEKLSLLMWYFMRVT 285
Query: 152 GIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGI 211
+ + ML L KL+L T +P++ +I G + + ++ +A+ + V E+ + +
Sbjct: 286 FLFIFMLNLSWKLSLFTAMGLPIIWVIPKISGKWYQELGAKVQKSLAQANDVATETFSSM 345
Query: 212 ETIRAFGKEKDVEKEFSKVSTETIKAYLR-VAIYMGIFWPLMNIASLLSVIVVIAYGGYL 270
+T+R+F E+ + + K +T A Y W +++SL + ++ YGG L
Sbjct: 346 KTVRSFANEEGETEHYRKRLEKTYSLNKEEAAAYAASTWT-NSMSSLFLKVSILYYGGSL 404
Query: 271 AYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEG- 329
G VS G +VAF+ Y +F + V+S Y S+ A+ E+I+E +D + EG
Sbjct: 405 VTGGTVSSGDLVAFVLYELQFSSAVEAVMSYYPSVMRAIGGSEKIFEYVDRQPQVPPEGT 464
Query: 330 ISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMR 387
++ + L+G +EF+NV F Y + PVLK ++L + P A+VG +GAGK+T +L+ R
Sbjct: 465 LAPQNLEGHVEFKNVTFTYPTREDTPVLKGLSLELRPGQITALVGASGAGKSTCVSLLER 524
Query: 388 FYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIR 447
FY P +GEIL DG + L +I V QE LF ++ ENI +A +E++ R
Sbjct: 525 FYLPQEGEILLDGQPLHSYKNQYLHDKISVVSQEPVLFARSVKENIKYGRDDATDEEMYR 584
Query: 448 VCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVD 507
+ H FI LP GY+T AGE G +S G++Q I++ARA+++ P I++LD+A S++D
Sbjct: 585 AAELANAHKFISDLPNGYDTDAGEKGGQVSGGQKQRIAIARALIRKPRILVLDDATSNLD 644
Query: 508 PKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
++E LV A++K + ++IAH+LS A+ ++V+++G+++EEGS ELL + G +
Sbjct: 645 TESEHLVHQALLKDSNPCSVLLIAHKLSTVEKANHIVVLEEGKVLEEGSHVELLEKGGTY 704
Query: 568 YKLYTSQ 574
L Q
Sbjct: 705 ADLVNKQ 711
>gb|AAG28766.1|AF300457_4 (AF300457) CoaD [Bacillus coagulans]
Length = 724
Score = 277 bits (700), Expect = 3e-73
Identities = 169/576 (29%), Positives = 314/576 (54%), Gaps = 7/576 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K S L + + ++R + +++ + + L ++A Y ++ ID Y+ L
Sbjct: 150 KESRHTLIDLVPLLIKQKRLIGLIITAAAITTLISIAGAYFFQLIIDTYLPHLMTNRLSL 209
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+A+ +++ Q +Q+F+T V GQ+++ ++ + + ++FF T+ G++ S
Sbjct: 210 VAIGLIVAYAFQAIINYIQSFFTIVLGQRLMIDIVLKYIHHLFDLPMNFFTTRHVGEMTS 269
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R +D + + D L S L + L + + + ++ L L +L VP+ + I F
Sbjct: 270 RF-SDASKIIDALGSTTLTLFLDMWILLAVGLFLAYQNINLFLCSLVVVPIYISIVWLFK 328
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
R ++T + A ++S + ES++GIETI++ E +K+ + ++ + L
Sbjct: 329 KTFNRLNQDTMESNAVLNSAIIESLSGIETIKSLTGEATTKKKIDTLFSDLLHKNLAYQK 388
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
+ L+ IV++ +G + + +S+G ++ + F P+ N++++
Sbjct: 389 ADQGQQAIKAATKLILTIVILWWGTFFVMRHQLSLGQLLTYNALLAYFLTPLENIINLQP 448
Query: 304 SLQSALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLY 361
LQ+A A R+ E+ ++ E + E ++E+L G+IEF +V F Y +L+DV+L
Sbjct: 449 KLQAARVANNRLNEVYLVESEFSKSREITALEQLNGDIEFNHVSFNYGYCSNILEDVSLT 508
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTK--GEILYDGIDGKKISRKSLRKRIGYVP 419
IP K+ IVG +G+GKTT+A L++ F++P + GEI + + ISR LR+ I YVP
Sbjct: 509 IPHHQKITIVGMSGSGKTTLAKLLVGFFEPQEQHGEIQINHHNISDISRTILRQYINYVP 568
Query: 420 QETYLFPGTIMENILM-ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
QE ++F G+++EN+L+ + P ++ + + C I I LP+GY T E+G LS
Sbjct: 569 QEPFIFSGSVLENLLLGSRPGVTQQMIDQACSFAEIKTDIENLPQGYHTRLSESGFNLSG 628
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G++Q +S+ARA+L I DE+ S++D TE + + ++ LM+ +T I +AHRL+I
Sbjct: 629 GQKQRLSIARALLSPAQCFIFDESTSNLDTITEHKIVSKLL-LMKDKTIIFVAHRLNIAS 687
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
DKV+V+D G+IVE+GS +LL+ GY+ +L +Q
Sbjct: 688 QTDKVVVLDHGKIVEQGSHRQLLNHNGYYARLIHNQ 723
>emb|CAB60586.1| (AL117200) contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=228.4, E-value=3.4e-65, N=1; PF00664
(ABC transporter transmembrane region.), Score=121.9,
E-value=3.9e-33, N=1 [Caenorhabditis elegans]
Length = 807
Score = 276 bits (699), Expect = 4e-73
Identities = 158/498 (31%), Positives = 264/498 (52%), Gaps = 20/498 (4%)
Query: 95 RNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGII 154
RN+R L IL ++ FF TG L+SRI D+ +++ L + + + L G
Sbjct: 304 RNIRVSLFRAILHQDISFFDDNKTGQLMSRITKDSESISNSLPVYIETTVNNSFMLFGSA 363
Query: 155 VAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETI 214
M +L + T + P++++ ++G + + + A + VEE ++ I T+
Sbjct: 364 PIMFYYSWQLAISTFVTFPIILLTTKFYGLIVEKLSEKENDATAVSNETVEEVLSAIRTV 423
Query: 215 RAFGKEKDVEKEFS-------KVSTETIKAYLRVAIYMGIFWPLM-NIASLLSVIVVIAY 266
R+F EK ++ K+ST+T+ + FW M NI +++ Y
Sbjct: 424 RSFAAEKIENMRYTRDTDAWFKISTKTVV----FGTFFNYFWATMWNIED----VIIYLY 475
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVED 326
GGYL G + ++ +I Y R +N S++ + + + ++ I++ + D
Sbjct: 476 GGYLTLNGRMEPDALLTYIFYHWRLHSALNAFSSLFSDVMKTIGSSRKVIHIMNRQPELD 535
Query: 327 YE-GISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
YE G ++ G I F +V F Y K VL +NL I P +A+VG +G GK+T+ +
Sbjct: 536 YEFGTETPEIVGNIIFEDVEFAYPTRKNANVLNKINLSIDPGKTIALVGPSGNGKSTLVS 595
Query: 384 LIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEE 443
LI +FY P G IL DG + I I V QE LF GT+ ENIL +E
Sbjct: 596 LIQQFYTPQSGRILIDGTPIQNIDHLHYHTNIALVAQEPTLFSGTVRENILYGLENGTDE 655
Query: 444 DVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEAL 503
D++RV + +H+F+ K+ KGY+T GE G +S G++Q I++ARA+++DP ++ILDEA
Sbjct: 656 DMMRVAEMANVHEFVSKMEKGYDTKCGEKGVQMSGGQKQRIAIARALIRDPRVLILDEAT 715
Query: 504 SSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELL-S 562
S++D ++E +VQ A+ + RT ++IAHRLS R AD++ V++ G + E G+ EL+ +
Sbjct: 716 SALDSESEAMVQEALNRCARERTVLVIAHRLSTVRSADRIAVIEKGNVTEMGNHEELMKN 775
Query: 563 RKGYFYKLYTSQMQEVPG 580
+G +YKL + Q+ + G
Sbjct: 776 TEGLYYKLVSKQLDPLIG 793
>pir||S58356 pepT protein - Staphylococcus epidermidis >gi|2126599|pir||S66651
pepT protein - Staphylococcus epidermidis
>gi|945015|emb|CAA90021.1| (Z49865) PepT [Staphylococcus
epidermidis]
Length = 571
Score = 276 bits (699), Expect = 4e-73
Identities = 171/552 (30%), Positives = 302/552 (53%), Gaps = 12/552 (2%)
Query: 27 VVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYT 86
+++S +GS + + P + ID ++ + EL FI L L+ L+ F+ L F
Sbjct: 25 IIISSIGS-ITEIIVPLLTGNLID--LLVKQTLELKFIVFLILMFLLDA-IFSGLGLFLL 80
Query: 87 EVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGS 146
G+K++ ++RS L + IL N FF +G L+SRI +DT+++N+ + L + S
Sbjct: 81 IKVGEKIIYSIRSILWKHILFLNTSFFDKNESGQLISRITDDTSLINNFISQKLPAIIPS 140
Query: 147 ILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEE 206
++L G I + ++D K+TL+T +P+ +++ + G + + +T+QK+A + +
Sbjct: 141 FITLIGSITMLFIMDWKMTLLTFIIIPIFLMVIIPLGNIIEKLSFKTQQKVADFTGTIGR 200
Query: 207 SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAY 266
++ I ++ E+ + + K ++ A + I P +I L+ + ++++Y
Sbjct: 201 VISAIRLVKISTNEEFELNNTKEKLSSIYKLNIKHAKIIAILQPFTSILLLVMIGIILSY 260
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD---DEN 323
GGY GA++ G +V+ I Y + PI+ + ++ +S+ A +RIY IL+ +EN
Sbjct: 261 GGYRIAVGAITSGTLVSMIFYVIQLSSPISEISTLITEYKSSKGASKRIYGILNEPVEEN 320
Query: 324 VEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
+ E I K E+ F +V+F Y+ + VL++V+ +P K AIVG +G+GK+TI N
Sbjct: 321 KVNLENIPQNK---ELIFNSVYFSYD-SKNVLENVSFAVPINKKTAIVGPSGSGKSTILN 376
Query: 384 LIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEE 443
LI R Y G I Y G I K R ++GYV Q + G+I +NIL +
Sbjct: 377 LISRLYKADSGGIYYGGHSIYDIDLKKWRIKLGYVMQNNIMMNGSIRDNILYGVSNNISD 436
Query: 444 DVIRVCKEL-GIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEA 502
D + L HDFI LP Y++ GE+G LS G++Q I++AR ++K+PDI++LDEA
Sbjct: 437 DELEYYSILANSHDFISNLPHQYDSQIGESGIKLSGGQKQRINIARNLIKNPDILLLDEA 496
Query: 503 LSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLS 562
+S+D ++E+ +QNA+ L + RT+III + R AD++I +D+G+I G+ L+
Sbjct: 497 TASLDSESEKKIQNALNNLFQNRTTIIIGIAYRLLRTADQIIFLDNGKITGIGTHHYLIK 556
Query: 563 RKGYFYKLYTSQ 574
+ ++Q
Sbjct: 557 NHNKYNTFVSNQ 568
>sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN 1 IN GLVBC
3'REGION >gi|7445716|pir||E69802 ABC transporter
(ATP-binding protein) homolog yfiB - Bacillus subtilis
>gi|1486244|dbj|BAA09106.1| (D50543) unknown [Bacillus
subtilis] >gi|2633145|emb|CAB12650.1| (Z99108) similar
to ABC transporter (ATP-binding protein) [Bacillus
subtilis]
Length = 573
Score = 276 bits (699), Expect = 4e-73
Identities = 169/554 (30%), Positives = 296/554 (52%), Gaps = 11/554 (1%)
Query: 26 IVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFY 85
I ++ ++ L P ++ ID I+ + + + + V + L +FY
Sbjct: 17 IALILMLTELAVELMQPLLIAKIIDDGILKQDLRHVWIWGTVMIGLTVLSFAAGMLNSFY 76
Query: 86 TEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLG 145
Q + R L +KI + F S+ ++R+ ND V +++ L L
Sbjct: 77 AAHVSQSFSYDTRKGLFQKIQSFSYSTFGQFSSSSYITRLTNDVTQVQNMIFMSLRFMLR 136
Query: 146 SILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVE 205
+ L +AG IV L ++VKL L ++P++++ L+ K +R ++++ +++++++
Sbjct: 137 APLMIAGGIVLSLAVNVKLGFFLLVTIPILILFLLWVLRKGGALFRSVQKRLDQVNTIMQ 196
Query: 206 ESVAGIETIRAFGKEKDVEKEFSKVST----ETIKAYLRVAIYMGIFWPLMNIASLLSVI 261
E++ I+ I+A + K F K +T +T+ A+ V M + LMN L ++
Sbjct: 197 ENLIAIKLIKALLRGSHEVKRFIKANTRLMEKTVSAFQLVEFTMPVLMLLMN----LCIL 252
Query: 262 VVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD 321
+++ G Y G+ +G VVA I YA R G ++ + A A+ +RI E+L+
Sbjct: 253 LILWAGSYSITSGSTQVGDVVAIINYATRITGALSMFPFLIMIFTRAKASGDRIGEVLET 312
Query: 322 ENVEDYEGISVEKLKGEIEFRNVWFEY-EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTT 380
E E EG ++L G IEF++V F Y E R L++V+ P +AI+G TG+GK+T
Sbjct: 313 EGDEREEGTISDRLSGRIEFQHVSFRYPEMDREALRNVSFSAKPRETIAILGATGSGKST 372
Query: 381 IANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEA 440
+ LI R Y P G I D + I + LR++IGYVPQE LF GTI ENI A
Sbjct: 373 LFQLIPRLYQPDSGRIYIDEKPVQDIPAEGLRRQIGYVPQEVLLFSGTIKENIAWGKENA 432
Query: 441 KEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILD 500
++++ K IH+ I+KLP GY+T G+ G LS G++Q IS+ARA+++ P I++LD
Sbjct: 433 SLDEIMDAAKLAQIHETILKLPNGYDTVLGQRGVNLSGGQKQRISIARALIRKPAILLLD 492
Query: 501 EALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGEL 560
++ S++D +TE + A+ T++II +++ AD++++++DG ++E+G+ EL
Sbjct: 493 DSTSALDLQTEAKLLEAISTY--HCTTLIITQKITTAMKADQILLLEDGELIEKGTHSEL 550
Query: 561 LSRKGYFYKLYTSQ 574
LS + ++Y SQ
Sbjct: 551 LSESQLYKRIYESQ 564
>pir||T31617 hypothetical protein Y50E8A.m - Caenorhabditis elegans
Length = 2055
Score = 276 bits (699), Expect = 4e-73
Identities = 158/498 (31%), Positives = 264/498 (52%), Gaps = 20/498 (4%)
Query: 95 RNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGII 154
RN+R L IL ++ FF TG L+SRI D+ +++ L + + + L G
Sbjct: 1552 RNIRVSLFRAILHQDISFFDDNKTGQLMSRITKDSESISNSLPVYIETTVNNSFMLFGSA 1611
Query: 155 VAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETI 214
M +L + T + P++++ ++G + + + A + VEE ++ I T+
Sbjct: 1612 PIMFYYSWQLAISTFVTFPIILLTTKFYGLIVEKLSEKENDATAVSNETVEEVLSAIRTV 1671
Query: 215 RAFGKEKDVEKEFS-------KVSTETIKAYLRVAIYMGIFWPLM-NIASLLSVIVVIAY 266
R+F EK ++ K+ST+T+ + FW M NI +++ Y
Sbjct: 1672 RSFAAEKIENMRYTRDTDAWFKISTKTVV----FGTFFNYFWATMWNIED----VIIYLY 1723
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVED 326
GGYL G + ++ +I Y R +N S++ + + + ++ I++ + D
Sbjct: 1724 GGYLTLNGRMEPDALLTYIFYHWRLHSALNAFSSLFSDVMKTIGSSRKVIHIMNRQPELD 1783
Query: 327 YE-GISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
YE G ++ G I F +V F Y K VL +NL I P +A+VG +G GK+T+ +
Sbjct: 1784 YEFGTETPEIVGNIIFEDVEFAYPTRKNANVLNKINLSIDPGKTIALVGPSGNGKSTLVS 1843
Query: 384 LIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEE 443
LI +FY P G IL DG + I I V QE LF GT+ ENIL +E
Sbjct: 1844 LIQQFYTPQSGRILIDGTPIQNIDHLHYHTNIALVAQEPTLFSGTVRENILYGLENGTDE 1903
Query: 444 DVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEAL 503
D++RV + +H+F+ K+ KGY+T GE G +S G++Q I++ARA+++DP ++ILDEA
Sbjct: 1904 DMMRVAEMANVHEFVSKMEKGYDTKCGEKGVQMSGGQKQRIAIARALIRDPRVLILDEAT 1963
Query: 504 SSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELL-S 562
S++D ++E +VQ A+ + RT ++IAHRLS R AD++ V++ G + E G+ EL+ +
Sbjct: 1964 SALDSESEAMVQEALNRCARERTVLVIAHRLSTVRSADRIAVIEKGNVTEMGNHEELMKN 2023
Query: 563 RKGYFYKLYTSQMQEVPG 580
+G +YKL + Q+ + G
Sbjct: 2024 TEGLYYKLVSKQLDPLIG 2041
>gb|AAD29140.1|AF099088_9 (AF099088) EntT [Enterococcus faecium]
Length = 717
Score = 275 bits (695), Expect = 1e-72
Identities = 167/573 (29%), Positives = 306/573 (53%), Gaps = 7/573 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K ++ L F+ ++ + +V++ + + S Y + +D +I L
Sbjct: 145 KEKVAGLSSFLPIIWKQKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNI 204
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
I++ + + + F +++ + GQ++ + Q + +L ++FF T+ +G+++S
Sbjct: 205 ISIGLIAVYLFRVLFEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIIS 264
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R ++ + ++ D L S L I + + V + + + L L+TL S+P V+ F
Sbjct: 265 RFLDASKII-DALASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFV 323
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
++ RE A ++S + ES+ GIETI+A+ E+ V + +K R
Sbjct: 324 KSYEKSNREEMAAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVT 383
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
I + ++ L+S +++ G Y +S+G ++ + F P+ N++++
Sbjct: 384 LDNIQQGIKHLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFFTDPLQNIINLQV 443
Query: 304 SLQSALAALERIYEIL---DDENVEDYEGISVEKL-KGEIEFRNVWFEYEKGRPVLKDVN 359
+Q+A A R+ EI +++ + +E + E+L + +I +NV F Y P L +++
Sbjct: 444 KMQTAQVANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEIS 503
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
IP SK AIVG +G+GK+T+A L +RFY+ ++G I Y I+ I + LR R+ Y+P
Sbjct: 504 CTIPSHSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLP 563
Query: 420 QETYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
QE++ F GTI+EN++ + E +I VC+ + +++FI + P YET E G LS
Sbjct: 564 QESFFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSG 623
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQ ++LARA+LK+PDI+ILDEA S +D E + N ++ L E +T I IAH L I +
Sbjct: 624 GQRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKE-KTIIFIAHHLPIAK 682
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLY 571
D+++V+ +G +VE+G+ EL G + KL+
Sbjct: 683 ACDQILVLHEGHLVEKGTHDELRFADGIYQKLW 715
>gb|AAC44070.1| (U51197) unknown [Sphingomonas sp. S88]
Length = 728
Score = 275 bits (695), Expect = 1e-72
Identities = 174/560 (31%), Positives = 287/560 (51%), Gaps = 11/560 (1%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQ----W 76
RR V+ + L LA+P + + ID ++ L +A +L V + W
Sbjct: 166 RRLFLEVLGITLALNLLGLAAPLLFQSVIDKVLVHNSMSTLSVLAFAFLAVSVWEVALGW 225
Query: 77 FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVL 136
T L T T QK+ L ++L +L L +F+ + GD V+R+ + + L
Sbjct: 226 IRTRLFTETT----QKIDVELGARLFHHLLALPLGYFEKRRVGDTVTRV-RQLETIREFL 280
Query: 137 VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
+ L + L + AML L V + S+ +++ G +R + +K
Sbjct: 281 TNASLTVMVDPLFTVVFLGAMLFYSPMLFGVVIVSLVAYAMVSFGVAGPLRTRVEDKFEK 340
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
+ ++++ ESV+GI TI+A E + + + + R+ + + S
Sbjct: 341 SSASNALLVESVSGIHTIKATAVEPHWQNRWERQLAAYTASSQRLINVANTGSQAIELIS 400
Query: 257 LLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
LS ++ +G GA+S+G +VAF +AQR GP+ + ++ Q A+ER+
Sbjct: 401 KLSFAAILFFGAKAVIGGAMSVGALVAFNMFAQRVSGPVIRMAQLWQDFQQVRIAIERLG 460
Query: 317 EILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVAIVGKT 374
++L+ ++ L+G I F NV F Y + +P VL D+ L IP + + IVG +
Sbjct: 461 DVLNHPVEPRPASAATLPVLRGAIRFENVTFRYAEDQPPVLSDITLDIPAGTSLGIVGSS 520
Query: 375 GAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENIL 434
G+GK+T+A L+ R P G +L D +D ++ LR++IG V QE LF +I ENI
Sbjct: 521 GSGKSTLAKLLQRLNTPDLGRVLVDEVDVAQLDPAWLRRQIGVVLQENLLFSRSIRENIA 580
Query: 435 MANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDP 494
++NP E V+ G HDFI++ P+GY+T E G LS G+RQ +++ARA++ +P
Sbjct: 581 LSNPAMPFEHVVAAATLAGAHDFILRQPRGYDTEIVERGVNLSGGQRQRLAIARALVGNP 640
Query: 495 DIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEE 554
I++ DEA S++D ++E+L+QN + + GRT +IIAHRLS R D++I ++ GRIVE
Sbjct: 641 RILVFDEATSALDAESEELIQNNLRAISAGRTLVIIAHRLSAVRACDRIITLEQGRIVES 700
Query: 555 GSPGELLSRKGYFYKLYTSQ 574
G ELL G + L+ Q
Sbjct: 701 GRHDELLRLGGRYADLHRRQ 720
>gb|AAF15371.1|U66588_3 (U66588) PaxB [Pasteurella aerogenes]
Length = 711
Score = 273 bits (692), Expect = 3e-72
Identities = 168/568 (29%), Positives = 294/568 (51%), Gaps = 5/568 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ V++ + L L +P +V +D ++ + L I + + +
Sbjct: 147 FIPAIIKYRKIFVEVMIVSIFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALAIVV 206
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + + L+T+ ++ L ++L +L + +F+ + GD V+R+ + + +
Sbjct: 207 IFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLALPISYFENRRVGDTVARV-RELDQI 265
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLT+V L S+P + +++ +RR E
Sbjct: 266 RNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTIVILLSLPCYIAWSIFISPILRRRLDE 325
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A + + ESV I+TI+A + + K + A RV + I +
Sbjct: 326 KFTRNADNQAFLVESVTAIDTIKALAVTPQMTNIWDKQLASYVSADFRVTVLATIGQQGV 385
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++AF + + P+ + ++ Q ++
Sbjct: 386 QLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISI 445
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E+++G +S+ ++ G++ F+N+ F Y+ P+ L DVNL I + I
Sbjct: 446 TRLGDVLNAPT-ENFQGKLSLPEINGDVTFKNIRFRYKPDAPIILNDVNLTIKQGEVIGI 504
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 505 VGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIR 564
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI + +P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 565 DNIALTDPSMPMEQVIHAAKLAGAHDFISELREGYNTMVGEQGAGLSGGQRQRIAIARAL 624
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M ++ GRT IIIAHRLS R AD++IV++ G
Sbjct: 625 VNNPRILIFDEATSALDYESEHIIMRNMQQICHGRTVIIIAHRLSTVRKADRIIVMEKGH 684
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQEV 578
IVE G ELL K Y Y +Q+Q +
Sbjct: 685 IVERGKHSELLENKDGLY-YYLNQLQSI 711
>sp|P08716|HLYB_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, PLASMID
>gi|95928|pir||S10057 ABC-type transport system
ATP-binding protein hlyB [validated] - Escherichia coli
plasmid pHly152 >gi|150683|gb|AAA98234.1| (M14107)
hemolysin B [Escherichia coli] >gi|225075|prf||1208296C
hemolysin hlyB [Escherichia coli]
Length = 707
Score = 273 bits (691), Expect = 4e-72
Identities = 178/566 (31%), Positives = 293/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + RR +V V L L +P +V +D ++ + L I + + +
Sbjct: 143 FIPAIIKYRRIFIETLVVSVFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVV 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
V + + L+T+ ++ L ++L +L + +F+++ GD V+R+ +
Sbjct: 203 VFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARVRELDQIR 262
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L + SL V M KLTLV L S+P +++ +RR +
Sbjct: 263 NFLTGQALTSVLDLLFSLIFFAV-MWYYSPKLTLVILFSLPCYAAWSVFISPILRRRLDD 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + A +V + I +
Sbjct: 322 KFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLATIGQQGI 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 382 QLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVAPVIRLAQIWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPVLKD-VNLYIPPASKVAI 370
R+ ++L+ E Y G +++ ++ G+I FRN+ F Y+ PV+ D +NL I + I
Sbjct: 442 TRLGDVLNSPT-ESYHGKLTLPEINGDITFRNIRFRYKPDSPVILDNINLSIKQGEVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ LI RFY P G++L DG D LR+++G V Q+ L +I+
Sbjct: 501 VGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSII 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +ANP E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 561 DNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M K+ +GRT IIIAHRLS + AD++IV++ G+
Sbjct: 621 VNNPKILIFDEATSALDYESEHVIMRNMHKICKGRTVIIIAHRLSTVKNADRIIVMEKGK 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELLS Y Y Q+Q
Sbjct: 681 IVEQGKHKELLSEPESLYS-YLYQLQ 705
>gb|AAG26952.1|AC069471_13 (AC069471) P-glycoprotein, putative [Arabidopsis thaliana]
Length = 1245
Score = 273 bits (690), Expect = 5e-72
Identities = 186/601 (30%), Positives = 314/601 (51%), Gaps = 41/601 (6%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASP-YILRVAIDHYIIPGRY--- 58
D SS S++ IK E ++ +G+ LA +P + + +A Y++ Y
Sbjct: 660 DFSSSSMIWELIKLNSPE---WPYALLGSIGAVLAGAQTPLFSMGIA---YVLTAFYSPF 713
Query: 59 -----KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF 113
+++ +A+++ + + LQ ++ + G+++ +R L IL + + +F
Sbjct: 714 PNVIKRDVEKVAIIFAGAGIVTAPIYLLQHYFYTLMGERLTSRVRLSLFSAILSNEIGWF 773
Query: 114 KT--KSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTS 171
+TG L S + D +V L L + ++ + ++ V
Sbjct: 774 DLDENNTGSLTSILAADATLVRSALADRLSTIVQNLSLTVTALALAFFYSWRVAAVVTAC 833
Query: 172 VPLMVIIALY-------FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVE 224
PL++ +L FGG RAY ++ +SV E++A I T+ A+G EK +
Sbjct: 834 FPLLIAASLTEQLFLKGFGGDYTRAY-------SRATSVAREAIANIRTVAAYGAEKQIS 886
Query: 225 KEFS-KVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVA 283
++F+ ++S T A++R I G + L + S + + Y L + G +
Sbjct: 887 EQFTCELSKPTKNAFVRGHI-SGFGYGLSQFLAFCSYALGLWYVSVLINHKETNFGDSIK 945
Query: 284 FIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE---NVEDYEGISVEKLKGEIE 340
++ +++ + AL ++ +L E + + V ++KG+IE
Sbjct: 946 SFMVLIVTAFSVSETLALTPDIVKGTQALGSVFRVLHRETKISPDQPNSRMVSQVKGDIE 1005
Query: 341 FRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEIL 397
FRNV F Y RP + K++NL + +A+VG +G+GK+T+ LIMRFYDP+ G +
Sbjct: 1006 FRNVSFVYPT-RPEIDIFKNLNLRVSAGKSLAVVGPSGSGKSTVIGLIMRFYDPSNGNLC 1064
Query: 398 YDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDF 457
DG D K ++ +SLRK++ V QE LF TI ENI N A E +++ K H+F
Sbjct: 1065 IDGQDIKTLNLRSLRKKLALVQQEPALFSTTIYENIKYGNENASEAEIMEAAKAANAHEF 1124
Query: 458 IMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNA 517
I+K+ +GY+T AG+ G LS G++Q +++ARA+LKDP +++LDEA S++D +E+LVQ A
Sbjct: 1125 IIKMEEGYKTHAGDKGVQLSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSSEKLVQEA 1184
Query: 518 MIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
+ KLM+GRT++++AHRLS R AD V V+ GR+VE+GS EL+S FYK TS +QE
Sbjct: 1185 LDKLMKGRTTVLVAHRLSTIRKADTVAVLHKGRVVEKGSHRELVSIPNGFYKQLTS-LQE 1243
Query: 578 V 578
V
Sbjct: 1244 V 1244
Score = 235 bits (594), Expect = 8e-61
Identities = 162/527 (30%), Positives = 264/527 (49%), Gaps = 22/527 (4%)
Query: 63 FIAMLYLLSLVAQWFFTT--LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKST-G 119
++ L L++ V+ W + +QT G++ LR + IL ++ FF T++
Sbjct: 95 YLVYLGLVNFVSAWIGVSCWMQT------GERQTARLRINYLKSILAKDITFFDTEARDS 148
Query: 120 DLVSRIINDTNVVNDVL---VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+L+ I +D +V D + +L L + AG ++ L + +LTL+TL VPL+
Sbjct: 149 NLIFHISSDAILVQDAIGDKTDHVLRYLSQFI--AGFVIGFLSV-WQLTLLTLGVVPLIA 205
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
I + M ++ A V EE ++ + T+ AF E+ K +S + +K
Sbjct: 206 IAGGGYAIVMSTISEKSETAYADAGKVAEEVMSQVRTVYAFVGEEKAVKSYSNSLKKALK 265
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
R + G+ L + +++ Y L G + I +
Sbjct: 266 LGKRSGLAKGLGVGLTYSLLFCAWALLLWYASLLVRHGKTNGAKAFTTILNVIFSGFALG 325
Query: 297 NVVSMYDSLQSALAALERIYEILDDENVEDY----EGISVEKLKGEIEFRNVWFEYEKGR 352
++ A I+ ++ + N E EG +++ + G IEF+ V F Y R
Sbjct: 326 QAAPSLSAIAKGRVAAANIFRMIGNNNSESSQRLDEGTTLQNVAGRIEFQKVSFAYPS-R 384
Query: 353 P--VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
P V ++++ I A VG +G+GK+TI +++ RFY+P GEIL DG D K + K
Sbjct: 385 PNMVFENLSFTIRSGKTFAFVGPSGSGKSTIISMVQRFYEPNSGEILLDGNDIKSLKLKW 444
Query: 411 LRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAG 470
R+++G V QE LF TI NIL+ A + +I K FI LP GY T G
Sbjct: 445 FREQLGLVSQEPALFATTIASNILLGKENANMDQIIEAAKAANADSFIKSLPNGYNTQVG 504
Query: 471 EAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
E G LS G++Q I++ARA+L++P I++LDEA S++D ++E++VQ A+ +ME RT+I++
Sbjct: 505 EGGTQLSGGQKQRIAIARAVLRNPKILLLDEATSALDAESEKIVQQALDNVMEKRTTIVV 564
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
AHRLS R DK++V+ DG++ E GS EL+ R G + L Q E
Sbjct: 565 AHRLSTIRNVDKIVVLRDGQVRETGSHSELMLRGGDYATLVNCQETE 611
>pir||LEECB hemolysin secretion protein hlyB - Escherichia coli
>gi|146383|gb|AAA23978.1| (M81823) hemolysoin B
[Escherichia coli]
Length = 707
Score = 272 bits (689), Expect = 6e-72
Identities = 175/566 (30%), Positives = 293/566 (50%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + RR +V V L L +P +V +D ++ + L I + + +
Sbjct: 143 FIPAIIKYRRIFIETLVVSVFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVV 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
V + + L+T+ ++ L ++L +L + +F+++ GD V+R+ + + +
Sbjct: 203 VFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARV-RELDQI 261
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLTLV L S+P +++ +RR +
Sbjct: 262 RNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYAAWSVFISPILRRRLDD 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + A +V + I +
Sbjct: 322 KFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLATIGQQGI 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 382 QLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVAPVIRLAQIWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPVLKD-VNLYIPPASKVAI 370
R+ ++L+ E Y G +++ ++ G+I FRN+ F Y+ PV+ D +NL I + I
Sbjct: 442 TRLGDVLNSPT-ESYHGKLALPEINGDITFRNIRFRYKPDSPVILDNINLSIKQGEVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ LI RFY P G++L DG D LR+++G V Q+ L +I+
Sbjct: 501 VGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSII 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +ANP E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 561 DNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M K+ +GRT IIIAHRLS + AD++IV++ G+
Sbjct: 621 VNNPKILIFDEATSALDYESEHIIMRNMHKICKGRTVIIIAHRLSTVKNADRIIVMEKGK 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELLS Y Y Q+Q
Sbjct: 681 IVEQGKHKELLSEPESLYS-YLYQLQ 705
>emb|CAB05917.1| (Z83327) transport-associated protein [Salmo salar]
Length = 739
Score = 272 bits (689), Expect = 6e-72
Identities = 157/487 (32%), Positives = 274/487 (56%), Gaps = 5/487 (1%)
Query: 92 KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLA 151
++ +++ + + +L+ + FF TGDLVSRI DTN +++ L L + + +
Sbjct: 226 RIHTSIQGLVFQSVLKQEIAFFDKAQTGDLVSRITTDTNDMSESLSEKLSLLMWYFMRVT 285
Query: 152 GIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGI 211
+ + ML L KL+L T +P++ +I G + + ++ +A+ + V E+ + +
Sbjct: 286 FLFLFMLNLSWKLSLFTAMGLPIIWVIPKISGKWHQELGAKVQKSLAQANDVATETFSSM 345
Query: 212 ETIRAFGKEKDVEKEFSKVSTETIKAYLR-VAIYMGIFWPLMNIASLLSVIVVIAYGGYL 270
+T+R+F E+ + + K +T A Y W +++SL + ++ YGG L
Sbjct: 346 KTVRSFANEEGETERYRKRLEKTYSLNKEEAAAYAASTWT-NSMSSLFLKVSILYYGGSL 404
Query: 271 AYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEG- 329
G VS G +VAF+ Y +F + V+S Y S+ A+ E+I+E +D + EG
Sbjct: 405 VTGGTVSSGDLVAFVLYELQFSSAVEAVMSYYPSVMRAIGGSEKIFEYVDRQPQVPPEGT 464
Query: 330 ISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMR 387
++ + L+G ++F+NV F Y + PVLK ++L + P A+VG +GAGK+T +L+ R
Sbjct: 465 LAPQNLEGHVQFKNVTFTYPTREDTPVLKGLSLELRPGQITALVGASGAGKSTCVSLLER 524
Query: 388 FYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIR 447
FY P +GEIL DG + L +I V QE LF ++ +NI +A +E++ R
Sbjct: 525 FYLPQEGEILLDGEPLHSYKNQYLHDKISVVSQEPVLFARSVKDNIKYGRDDATDEEIYR 584
Query: 448 VCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVD 507
+ H FI LP GY+T AGE G +S G++Q I++ARA+++ P I++LD+A S++D
Sbjct: 585 AAELANAHKFISDLPNGYDTDAGEKGGQVSGGQKQRIAIARALIRKPRILVLDDATSNLD 644
Query: 508 PKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
++E LV A++K + ++IAH+LS A+ ++V+++G+++EEGS ELL + G +
Sbjct: 645 TESEHLVHQALLKDSNPCSVLLIAHKLSTVEKANHIVVLEEGKVLEEGSHVELLEKGGTY 704
Query: 568 YKLYTSQ 574
L Q
Sbjct: 705 ADLVNKQ 711
>gb|AAD55753.1|AF108387_1 (AF108387) transporter associated with antigen processing 1
[Heterodontus francisci]
Length = 558
Score = 272 bits (688), Expect = 8e-72
Identities = 155/484 (32%), Positives = 265/484 (54%), Gaps = 5/484 (1%)
Query: 97 LRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVA 156
++S + +++ + FF T TGD+ SRI DTN +++ L L + ++ ++
Sbjct: 60 IQSSVFRSVVRQEIAFFDTVHTGDITSRITTDTNTMSESLTEKLSLLMWYLMRAVCLLAF 119
Query: 157 MLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRA 216
M L KLT+ TL +P+++II + G ++ E ++ +AK + V E+ ++T+R+
Sbjct: 120 MFNLSWKLTICTLIGIPIIIIIPEFTGKYYQKLSVEVQESLAKANDVAVETFLSMKTVRS 179
Query: 217 FGKEKDVEKEFSKVSTETIKAYLR-VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGA 275
F E + + + +T + + A Y G W +++ L+ + ++ YGG L G
Sbjct: 180 FANEDGESRRYGERLEDTFRLNKKEAAAYAGFMWT-NSLSGLVLKVTLLYYGGRLVAGGN 238
Query: 276 VSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEG-ISVEK 334
V+ G +V+FI Y +F + ++S+Y +++ A+ A E+++E +D G + +
Sbjct: 239 VTSGNLVSFILYEMQFTTAVEVLLSVYPNVKKAVGASEKVFEYMDRRPALSTVGTFAPVR 298
Query: 335 LKGEIEFRNVWFEYEK--GRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPT 392
K IEFRNV F Y K PVLK+V+ + A+VG +G GKTT +L+ RFY P
Sbjct: 299 PKAHIEFRNVTFAYPKRPDTPVLKNVSFELKCGKITALVGPSGGGKTTCVSLLERFYQPQ 358
Query: 393 KGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKEL 452
G+IL DG K+ K ++ V QE LF ++ +NI E VI K
Sbjct: 359 SGQILLDGKPIKEYEHKYYHNKVSLVSQEPVLFARSVEQNISYGLEGKPRESVIDAAKRA 418
Query: 453 GIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQ 512
H FI +L GY T AGE G LS G++Q +++ARA+++DP ++ILD+A S +D ++E
Sbjct: 419 NAHRFITELKDGYNTDAGEKGGQLSGGQKQRVAIARALIRDPRVLILDDATSCLDTESEH 478
Query: 513 LVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYT 572
+V ++ R ++IAHRLS AD ++V+++G +VE+G+ ELL + G + +L
Sbjct: 479 MVLQSVYNGDRQRAVLVIAHRLSTMEGADWIVVLENGSVVEQGTHQELLQKGGSYQQLLQ 538
Query: 573 SQMQ 576
+Q
Sbjct: 539 KHLQ 542
>sp|P36497|PEDD_PEDAC PEDIOCIN PA-1 TRANSPORT ATP-BINDING PROTEIN PEDD (PEDIOCIN ACH
TRANSPORT ATP-BINDING PROTEIN PAPD)
>gi|478102|pir||D48941 ATP-dependent transport protein
homolog PedD - Pediococcus acidilactici
>gi|150568|gb|AAA25561.1| (M83924) bacteriocin
operon-associated ORF; putative [Pediococcus
acidilactici] >gi|407300|gb|AAC43296.1| (U02482) papD
[Pediococcus acidilactici]
Length = 724
Score = 272 bits (687), Expect = 1e-71
Identities = 167/576 (28%), Positives = 312/576 (53%), Gaps = 7/576 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K S L + + ++R + +++ + + L ++A Y ++ ID Y+ L
Sbjct: 150 KESRHTLIDLVPLLIKQKRLIGLIITAAAITTLISIAGAYFFQLIIDTYLPHLMTNRLSL 209
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+A+ +++ Q +Q+F+T V GQ+++ ++ + + ++FF T+ G++ S
Sbjct: 210 VAIGLIVAYAFQAIINYIQSFFTIVLGQRLMIDIVLKYVHHLFDLPMNFFTTRHVGEMTS 269
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R +D + + D L S L + L + + + ++ L L +L VP+ + I F
Sbjct: 270 RF-SDASKIIDALGSTTLTLFLDMWILLAVGLFLAYQNINLFLCSLVVVPIYISIVWLFK 328
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
R ++T + A ++S + ES++GIETI++ E +K+ + ++ + L
Sbjct: 329 KTFNRLNQDTMESNAVLNSAIIESLSGIETIKSLTGEATTKKKIDTLFSDLLHKNLAYQK 388
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
+ L+ IV++ +G + + +S+G ++ + F P+ N++++
Sbjct: 389 ADQGQQAIKAATKLILTIVILWWGTFFVMRHQLSLGQLLTYNALLAYFLTPLENIINLQP 448
Query: 304 SLQSALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLY 361
LQ+A A R+ E+ ++ E + E ++E+L G+IE +V F Y +L+DV+L
Sbjct: 449 KLQAARVANNRLNEVYLVESEFSKSREITALEQLNGDIEVNHVSFNYGYCSNILEDVSLT 508
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTK--GEILYDGIDGKKISRKSLRKRIGYVP 419
IP K+ IVG +G+GKTT+A L++ F++P + GEI + + ISR LR+ I YVP
Sbjct: 509 IPHHQKITIVGMSGSGKTTLAKLLVGFFEPQEQHGEIQINHHNISDISRTILRQYINYVP 568
Query: 420 QETYLFPGTIMENILM-ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
QE ++F G+++EN+L+ + P ++ + + C I I LP+GY T E+G LS
Sbjct: 569 QEPFIFSGSVLENLLLGSRPGVTQQMIDQACSFAEIKTDIENLPQGYHTRLSESGFNLSG 628
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G++Q +S+ARA+L I DE+ S++D TE + + ++ M+ +T I +AHRL+I
Sbjct: 629 GQKQRLSIARALLSPAQCFIFDESTSNLDTITEHKIVSKLL-FMKDKTIIFVAHRLNIAS 687
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
DKV+V+D G+IVE+GS +LL+ GY+ +L +Q
Sbjct: 688 QTDKVVVLDHGKIVEQGSHRQLLNYNGYYARLIHNQ 723
>dbj|BAA96813.1| (AB040146) ABC transporter A [Thermus thermophilus]
Length = 578
Score = 271 bits (686), Expect = 1e-71
Identities = 179/579 (30%), Positives = 311/579 (52%), Gaps = 19/579 (3%)
Query: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE 60
M +S+ LL+R R V++ + S + +PY LR+A+D + GR
Sbjct: 1 MTGRSAAPLLRRLWPYVGRYRWRYLWAVLAGLASIFFFVLTPYFLRLAVDA-VQAGR--- 56
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTE----VFGQKVLRNLRSQLHEKILQSNLDFFKTK 116
GF +Y L++VA + L ++ V ++V +LR L +L + DF+
Sbjct: 57 -GF--GVYALAIVASAALSGLLSYAMRRLAVVASRQVEYDLRRDLLHHLLTLDRDFYHKH 113
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGII--VAMLLLDVKLTLVTLTSVPL 174
GDL++R+ D + V +++ G+L +GS LS ++ ++M ++ +L +P
Sbjct: 114 RVGDLMNRLNTDLSAVREMVGPGIL--MGSRLSFLVLLAFLSMYAVNARLAFYLTLILPG 171
Query: 175 MVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTET 234
+ + + + R YRE ++ +IS++ +E+ +GI ++ + E+ + F ++
Sbjct: 172 IFLAMRFLLRLIDRRYREAQEVFDRISTLAQEAFSGIRVVKGYALERRMVAWFQDLNRLY 231
Query: 235 IKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGP 294
++ L +A G L+ + + V+ GG + +G +S+G +V F Y + P
Sbjct: 232 VEKSLALARVEGPLHALLGFLMGFAFLTVLWAGGAMVVRGELSVGELVQFNAYLAQLTWP 291
Query: 295 INNVVSMYDSLQSALAALERIYEILDDENV---EDYEGISVEKLKGEIEFRNVWFEYEKG 351
I + + Q L +L R++E+LD++ ED +++E L GE+ F V + + G
Sbjct: 292 ILGLGWVMALYQRGLTSLRRLFELLDEKPAIRDEDPLPLALEDLSGEVRFEGVGLKRD-G 350
Query: 352 RPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
R +L+ + L IP + I G+TG+GK+ +A L+ R DP++G + G + ++I L
Sbjct: 351 RWLLRGLTLTIPEGMTLGITGRTGSGKSLLAALVPRLLDPSEGRVYVGGHEARRIPLAVL 410
Query: 412 RKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
RK +G PQE +LF TI+ENI E E V + GIH+ I+ PKGYET GE
Sbjct: 411 RKAVGVAPQEPFLFSETILENIAFGLDEVDRERVEWAARLAGIHEEILAFPKGYETVLGE 470
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G LS G+RQ ++LARA+ K P I+ILD+ALS+VD +TE + + ++ +T+++I+
Sbjct: 471 RGITLSGGQRQRVALARALAKRPKILILDDALSAVDAETEARILQGLKTVLGKQTTLLIS 530
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
HR + R AD +IV+D+GRIVEEG+ LL G + ++
Sbjct: 531 HRTAALRHADWIIVLDEGRIVEEGTHESLLQAGGLYAEM 569
>sp|P10089|HLY2_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, CHROMOSOMAL
>gi|146380|gb|AAA23976.1| (M10133) chromosomal hemolysin
B (hlyB) [Escherichia coli]
Length = 707
Score = 271 bits (685), Expect = 2e-71
Identities = 174/566 (30%), Positives = 293/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ +V V L L +P +V +D ++ + L I + + +
Sbjct: 143 FIPAIIKYRKIFIETLVVSVFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVV 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
V + + L+T+ ++ L ++L +L + +F+++ GD V+R+ + + +
Sbjct: 203 VFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARV-RELDQI 261
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLTLV L S+P +++ +RR +
Sbjct: 262 RNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYAAWSVFISPILRRRLDD 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + A +V + I +
Sbjct: 322 KFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLATIGQQGI 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 382 QLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVAPVIRLAQIWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPVLKD-VNLYIPPASKVAI 370
R+ ++L+ E Y G +++ ++ G+I FRN+ F Y+ PV+ D +NL I + I
Sbjct: 442 TRLGDVLNSPT-ESYHGKLALPEINGDITFRNIRFRYKPDSPVILDNINLSIKQGEVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ LI RFY P G++L DG D LR+++G V Q+ L +I+
Sbjct: 501 VGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSII 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +ANP E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 561 DNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M K+ +GRT IIIAHRLS + AD++IV++ G+
Sbjct: 621 VNNPKILIFDEATSALDYESEHVIMRNMHKICKGRTVIIIAHRLSTVKNADRIIVMEKGK 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELLS Y Y Q+Q
Sbjct: 681 IVEQGKHKELLSEPESLYS-YLYQLQ 705
>sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA >gi|281879|pir||S27998
probable ABC-type transport protein msbA - Escherichia
coli >gi|42023|emb|CAA77839.1| (Z11796) member of
ATP-dependent transport family, very similar to mdr
proteins and hemolysin B, export protein [Escherichia
coli] >gi|1651441|dbj|BAA35658.1| (D90729) MsbA protein.
[Escherichia coli] >gi|1787143|gb|AAC74000.1| (AE000193)
ATP-binding transport protein; multicopy suppressor of
htrB [Escherichia coli K12]
Length = 582
Score = 270 bits (684), Expect = 2e-71
Identities = 156/486 (32%), Positives = 269/486 (55%), Gaps = 4/486 (0%)
Query: 92 KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLA 151
KV+ +R +L ++ + FF +STG L+SRI D+ V L+ + S+
Sbjct: 95 KVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASII 154
Query: 152 GIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGI 211
G+ + M +L+++ + P++ I + R + + + ++++ E+ + G
Sbjct: 155 GLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGH 214
Query: 212 ETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLA 271
+ + FG ++ K F KVS +++ I P++ + + L++ V+ + +
Sbjct: 215 KEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPS 274
Query: 272 YKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGIS 331
+++ G + P+ ++ ++ Q +AA + ++ ILD E +D
Sbjct: 275 VMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV 334
Query: 332 VEKLKGEIEFRNVWFEYEKGR--PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFY 389
+E+ G++EFRNV F Y GR P L+++NL IP VA+VG++G+GK+TIA+LI RFY
Sbjct: 335 IERATGDVEFRNVTFTYP-GRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFY 393
Query: 390 DPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVC 449
D +GEIL DG D ++ + SLR ++ V Q +LF T+ NI A E + I
Sbjct: 394 DIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEA 453
Query: 450 KELGIH-DFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDP 508
+ DFI K+ G +T GE G LLS G+RQ I++ARA+L+D I+ILDEA S++D
Sbjct: 454 ARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDT 513
Query: 509 KTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFY 568
++E+ +Q A+ +L + RTS++IAHRLS AD+++VV+DG IVE G+ +LL +G +
Sbjct: 514 ESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYA 573
Query: 569 KLYTSQ 574
+L+ Q
Sbjct: 574 QLHKMQ 579
>sp|Q00564|LCNC_LACLA LACTOCOCCIN A TRANSPORT ATP-BINDING PROTEIN LCNC
>gi|282301|pir||B43943 ATP-dependent membrane
translocator homolog LcnC - Lactococcus lactis
Length = 715
Score = 270 bits (684), Expect = 2e-71
Identities = 171/578 (29%), Positives = 305/578 (52%), Gaps = 22/578 (3%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K S L FI +++ + +V++ L N+ Y L+ ID YI LG
Sbjct: 148 KEKASSLLSFIPIITRQKKVILNIVIASFIVTLINILGSYYLQSMIDSYIPNALMGTLGI 207
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
I++ LL+ + Q + F V Q++ ++ I Q + FF T+ TG++ S
Sbjct: 208 ISVGLLLTYIIQQVLEFAKAFLLNVLSQRLAIDVILSYIRHIFQLPMSFFSTRRTGEITS 267
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLL---DVKLTLVTLTSVPLMVIIAL 180
R +D + + D + S +L L L +++ L+L +++L L+ L ++PL +++ +
Sbjct: 268 RF-SDASSILDAIASTILS---LFLDLTIVVMTGLILGLQNMQLFLLVLLAIPLYIVVII 323
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
F + E Q A ++S + E + GIETI+A E++ + K+ E +YL+
Sbjct: 324 IFTPLFEKQNHEVMQTNAVLNSSIIEDINGIETIKALASEQE---RYQKIDYE-FASYLK 379
Query: 241 VAIYM----GIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
A + I + I L + ++ +G L +++G ++ F F PI
Sbjct: 380 KAFTLQKSEAIQGLIKAIIQLTLSVTILWFGATLVISQKITLGQLITFNALLSYFTNPIT 439
Query: 297 NVVSMYDSLQSALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPV 354
N++++ LQ A A ER+ E+ + E E +S+ + ++ ++Y GR V
Sbjct: 440 NIINLQTKLQKARVANERLNEVYLVPSEFEEKKTELSLSHFN--LNMSDISYQYGFGRKV 497
Query: 355 LKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKR 414
L ++ L I K+ IVG +G+GK+T+ L++ F+ PT G I GID ++ + LR+
Sbjct: 498 LSEIELSIKENEKLTIVGMSGSGKSTLVKLLVNFFQPTSGTITLGGIDLQQFDKHQLRRL 557
Query: 415 IGYVPQETYLFPGTIMENILM-ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAG 473
I Y+PQ+ Y+F G+I++N+L+ AN A +E++++ + I I ++ GY+T
Sbjct: 558 INYLPQQPYIFTGSILDNLLLGANENASQEEILKAVELAEIRADIEQMQLGYQTELSSDA 617
Query: 474 KLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHR 533
LS G++Q I+LARA+L I+ILDEA S++D TE+ + ++ L +T I IAHR
Sbjct: 618 SSLSGGQKQRIALARALLSPAKILILDEATSNLDMITEKKILKNLLPL--DKTIIFIAHR 675
Query: 534 LSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLY 571
LS+ + ++IVVD G+++E GS +LL++ G++ +LY
Sbjct: 676 LSVAEMSHRIIVVDQGKVIESGSHVDLLAQNGFYEQLY 713
>pir||S75352 ABC-type transport protein slr2019 - Synechocystis sp. (strain PCC
6803) >gi|1652343|dbj|BAA17266.1| (D90904) ABC
transporter [Synechocystis sp.]
Length = 593
Score = 270 bits (684), Expect = 2e-71
Identities = 164/555 (29%), Positives = 303/555 (54%), Gaps = 23/555 (4%)
Query: 38 NLASPYILRVAIDHYI-----IPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVF--- 89
+LA P ++ +A+D I R+ + + L +L+ VA L++ + +
Sbjct: 36 DLAPPALIGLAVDVVIKQQDSFLSRWGIVSVQSQLLVLT-VASAVIWALESIFEYAYERL 94
Query: 90 ----GQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVN---DVLVSGLLG 142
Q + +LR + + Q +L +F+ +STG L++ + +D N + DV + +L
Sbjct: 95 WRNLAQDIQHDLRLDAYAHLQQLDLAYFEERSTGRLMAILNDDINQLERFLDVGANEILQ 154
Query: 143 GLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISS 202
L +++ + G A ++ + + + +P +++ ++YF + Y R+K++ ++S
Sbjct: 155 VLTTVVVIGG---AFFVITPDIAWMAVVPMPFVLLGSIYFQSLLTSRYALVREKVSNLNS 211
Query: 203 VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIV 262
+ +++GI TI++F E + + + S + R F PL+ +
Sbjct: 212 RLSNNLSGIMTIKSFATEAEEVERLRQDSDAYRDSNQRAIALSAAFVPLIRVIIFAGFST 271
Query: 263 VIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE 322
++ +GG A +G +++G + QR P+ + D Q A+A+ +R+ ++L
Sbjct: 272 ILYFGGLDAVRGNLAVGSYSMLVFLTQRLLWPLTGLGKTLDLYQRAMASTQRVMQLLATP 331
Query: 323 NVEDYEG---ISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKT 379
++ + G + +++GE+ F+N+ F Y VLK+V+L +P + IVG TG+GK+
Sbjct: 332 -IQAHPGELSLHPSQVQGELVFQNISFAYPHRSAVLKNVSLRVPAGQTIGIVGATGSGKS 390
Query: 380 TIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPE 439
T+ L++R Y+ G+IL DG+D KK LR+ +G V Q+ +LF GT+ ENI + +
Sbjct: 391 TLVKLLLRLYEWDSGDILLDGVDLKKYFLGDLRRSVGLVSQDVFLFHGTVRENIAYGSAD 450
Query: 440 AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVIL 499
A + R +FI +LP+GY+T GE G+ LS G+RQ +++ARA+LK+P I+IL
Sbjct: 451 ATLAQIERAANLAEAEEFINQLPQGYDTIIGERGQKLSGGQRQRLAIARAILKNPPILIL 510
Query: 500 DEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGE 559
DEA S+VD +TE + ++ K+ + RT+I IAHRLS R+AD++ V+++G + E GS
Sbjct: 511 DEATSAVDNETEAAIVRSLEKITKNRTTITIAHRLSTVRYADQIYVLENGMVQEMGSHES 570
Query: 560 LLSRKGYFYKLYTSQ 574
LL+ +G + KL+ Q
Sbjct: 571 LLAHQGLYAKLWRVQ 585
>sp|P23702|HLYB_ACTAC LEUKOTOXIN SECRETION ATP-BINDING PROTEIN >gi|625795|pir||A61378
leukotoxin expression protein B - Actinobacillus
actinomycetemcomitans >gi|38647|emb|CAA37906.1| (X53955)
LKTB [Actinobacillus actinomycetemcomitans]
Length = 707
Score = 270 bits (682), Expect = 4e-71
Identities = 165/565 (29%), Positives = 290/565 (51%), Gaps = 3/565 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ + + L +P +V +D ++ + L I + + +
Sbjct: 143 FIPAVIKYRKIFIETLIVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNVITVALAIVV 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + L+T+ ++ L ++L +L + +F+ + GD V+R+ + + +
Sbjct: 203 LFEIILGGLRTYVFAHSTSRIDVELGARLFRHLLALPISYFEARRVGDTVARV-RELDQI 261
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLTLV L S+P VI +++ +RR +
Sbjct: 262 RNFLTGQALTSILDLLFSFIFFAVMWYYSPKLTLVVLGSLPCYVIWSVFISPILRRRLDD 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + +V + I +
Sbjct: 322 KFARNADNQSFLVESVTAINTIKAMAISPQMTNIWDKQLASYVAVSFKVTVLATIGQQGI 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +++ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 382 QLIQKAVMVINLWLGAHLVISGDLSIGQLIAFNMLAGQIISPVIRLAQIWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVAIV 371
R+ ++L+ + +S+ +++GEI FRN+ F Y+ P +L ++NL I + IV
Sbjct: 442 TRLGDVLNSPTENNTASVSLPEIQGEISFRNIKFRYKPDSPMILNNINLDISQGEVIGIV 501
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G++G+GK+T+ LI RFY P +G++L DG D LR+++G V Q+ L +I E
Sbjct: 502 GRSGSGKSTLTKLIQRFYIPEQGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIRE 561
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI + NP E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA++
Sbjct: 562 NIALTNPGMPMEKVIAAAKLAGAHDFISELREGYNTVVGEQGAGLSGGQRQRIAIARALV 621
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
+P I+I DEA S++D ++E ++ + M K+ + RT +IIAHRLS + AD++IV+D G I
Sbjct: 622 NNPRILIFDEATSALDYESENIIMHNMHKICQNRTVLIIAHRLSTVKNADRIIVMDKGEI 681
Query: 552 VEEGSPGELL-SRKGYFYKLYTSQM 575
+E+G ELL KG + L+ Q+
Sbjct: 682 IEQGKHQELLKDEKGLYSYLHQLQV 706
>pir||S51777 xIIIB protein - Actinobacillus pleuropneumoniae
>gi|558153|emb|CAA56359.1| (X80055) xIIIB
[Actinobacillus pleuropneumoniae]
Length = 711
Score = 270 bits (682), Expect = 4e-71
Identities = 166/566 (29%), Positives = 293/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ + L L +P +V +D ++ + L I + + +
Sbjct: 147 FIPAVIKYRKIFVETIIVSIFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVV 206
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + L+T+ ++ L ++L +L + +F+ + GD V+R+ + + +
Sbjct: 207 IFEIVLNGLRTYIFSHSTSRIDVELGAKLFRHLLALPISYFENRRVGDTVARV-RELDQI 265
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLT+V L S+P + +++ +RR E
Sbjct: 266 RNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTIVILLSLPCYIAWSIFISPILRRRLDE 325
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV+ I+TI+A + + K + A RV + I +
Sbjct: 326 KFARNADNQSFLVESVSAIDTIKALAVTPQMTNIWDKQLASYVSADFRVTVLATIGQQGV 385
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++AF + + P+ + ++ Q ++
Sbjct: 386 QLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVVRLAQLWQDFQQVGISI 445
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E+Y+G +S+ ++KG+I F+++ F Y+ P+ L DVNL + + I
Sbjct: 446 TRLGDVLNSPT-ENYQGKLSLPEIKGDIAFKHIRFRYKPDAPIILDDVNLSVKQGEVIGI 504
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 505 VGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIR 564
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI + +P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 565 DNIALTDPSMSMERVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARAL 624
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA ++D ++E ++ M K+ GRT IIIAHRLS + AD++IV++ G
Sbjct: 625 VNNPRILIFDEATRALDYESEHIIMQNMQKICHGRTVIIIAHRLSTVKNADRIIVMEKGH 684
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G +LL + Y Y +Q+Q
Sbjct: 685 IVEQGKHNQLLENENGLY-YYLNQLQ 709
>pir||C30169 leukotoxin expression protein B - Pasteurella haemolytica
Length = 708
Score = 269 bits (681), Expect = 5e-71
Identities = 170/567 (29%), Positives = 295/567 (51%), Gaps = 7/567 (1%)
Query: 13 FIKEALSERRT-LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS 71
FI + R+ L ++VSI A L +P +V +D ++ + L I + +
Sbjct: 144 FIPAVIKYRKIFLETLIVSIFLQIFA-LITPLFFQVVMDKVLVHRGFSTLNIITVALAIV 202
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
++ + + L+T+ ++ L ++L +L + +F+ + GD V+R+ + +
Sbjct: 203 IIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENRRVGDTVARV-RELDQ 261
Query: 132 VNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
+ + L L + +L M KLTLV L S+P ++ +++ +RR
Sbjct: 262 IRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYILWSIFISPILRRRLD 321
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
E + A + + ESV I I+A + + K + + RV + I
Sbjct: 322 EKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSSSFRVTVLATIGQQG 381
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ + +++ + G +L G +SIG ++AF + + P+ + ++ Q +
Sbjct: 382 VQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGIS 441
Query: 312 LERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVA 369
+ R+ ++L+ E Y+G +S+ ++KG+I F+N+ F Y+ P +L +VNL I +
Sbjct: 442 VTRLGDVLNSPT-EQYQGKLSLPEIKGDISFKNIRFRYKPDAPTILNNVNLEIRQGEVIG 500
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
IVG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 501 IVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSI 560
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI +++P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA
Sbjct: 561 RENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARA 620
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++ +P I+I DEA S++D ++E ++ M K+ +GRT I+IAHRLS + AD++IV++ G
Sbjct: 621 LVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHRLSTVKNADRIIVMEKG 680
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELL Y Y Q+Q
Sbjct: 681 EIVEQGKHHELLQNSNGLYS-YLHQLQ 706
>sp|P16532|HLYB_PASHA LEUKOTOXIN SECRETION ATP-BINDING PROTEIN >gi|97197|pir||A32051
leukotoxin B - Pasteurella haemolytica (serotype 1)
>gi|150495|gb|AAA25530.1| (M20730) LktB protein
[Pasteurella haemolytica]
Length = 708
Score = 269 bits (681), Expect = 5e-71
Identities = 170/567 (29%), Positives = 295/567 (51%), Gaps = 7/567 (1%)
Query: 13 FIKEALSERRT-LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS 71
FI + R+ L ++VSI A L +P +V +D ++ + L I + +
Sbjct: 144 FIPAVIKYRKIFLETLIVSIFLQIFA-LITPLFFQVVMDKVLVHRGFSTLNIITVALAIV 202
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
++ + + L+T+ ++ L ++L +L + +F+ + GD V+R+ + +
Sbjct: 203 IIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENRRVGDTVARV-RELDQ 261
Query: 132 VNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
+ + L L + +L M KLTLV L S+P ++ +++ +RR
Sbjct: 262 IRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYILWSIFISPILRRRLD 321
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
E + A + + ESV I I+A + + K + + RV + I
Sbjct: 322 EKFARSADNQAFLVESVTSINMIKAMAVAPQMTDTWDKQLASYVSSSFRVTVLATIGQQG 381
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ + +++ + G +L G +SIG ++AF + + P+ + ++ Q +
Sbjct: 382 VQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGIS 441
Query: 312 LERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVA 369
+ R+ ++L+ E Y+G +S+ ++KG+I F+N+ F Y+ P +L +VNL I +
Sbjct: 442 VTRLGDVLNSPT-EQYQGKLSLPEIKGDISFKNIRFRYKPDAPTILNNVNLEIRQGEVIG 500
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
IVG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 501 IVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSI 560
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI +++P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA
Sbjct: 561 RENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARA 620
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++ +P I+I DEA S++D ++E ++ M K+ +GRT I+IAHRLS + AD++IV++ G
Sbjct: 621 LVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHRLSTVKNADRIIVMEKG 680
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELL Y Y Q+Q
Sbjct: 681 EIVEQGKHHELLQNSNGLYS-YLHQLQ 706
>pir||E72396 ABC transporter, ATP-binding protein - Thermotoga maritima (strain
MSB8) >gi|4980785|gb|AAD35375.1|AE001710_10 (AE001710)
ABC transporter, ATP-binding protein [Thermotoga
maritima]
Length = 577
Score = 269 bits (681), Expect = 5e-71
Identities = 157/551 (28%), Positives = 297/551 (53%), Gaps = 11/551 (1%)
Query: 31 IVGSALANLASPYILRVAIDHYIIPGRYK---ELGFIAMLY-LLSLVAQWFFTTLQTFYT 86
+V + +L+ P +L +D I G + + G + ++ L+ V T ++ +
Sbjct: 22 MVVEVICDLSQPTLLARIVDEGIARGDFSLVLKTGILMLIVALIGAVGGIGCTVFASYAS 81
Query: 87 EVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGS 146
+ FG +LR L K+L ++ T L++R+ ND + ++++ L + +
Sbjct: 82 QNFGA----DLRRDLFRKVLSFSISNVNRFHTSSLITRLTNDVTQLQNLVMMLLRIVVRA 137
Query: 147 ILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEE 206
L G IV + ++VKL+ V + +P +V++ ++ K +R+ ++ +++ VV E
Sbjct: 138 PLLFVGGIVMAVSINVKLSSVLIFLIPPIVLLFVWLTKKGNPLFRKIQESTDEVNRVVRE 197
Query: 207 SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAY 266
++ G+ +RAF +E+ + F K + ++ + + PL + +I V+ +
Sbjct: 198 NLLGVRVVRAFRREEYENENFRKANESLRRSIISAFSLIVFALPLFIFIVNMGMIAVLWF 257
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENV-- 324
GG L + IG ++A+ Y + + + ++ + + A A+ +R+ E+L+++
Sbjct: 258 GGVLVRNNQMEIGSIMAYTNYLMQIMFSLMMIGNILNFIVRASASAKRVLEVLNEKPAIE 317
Query: 325 EDYEGISVEKLKGEIEFRNVWFEY-EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
E +++ ++G + F NV F Y E PVL VN + P S VA++G+TG+GK+T+ N
Sbjct: 318 EADNALALPNVEGSVSFENVEFRYFENTDPVLSGVNFSVKPGSLVAVLGETGSGKSTLMN 377
Query: 384 LIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEE 443
LI R DP +G + D +D + + K LR I VPQET LF GTI EN+ +A ++
Sbjct: 378 LIPRLIDPERGRVEVDELDVRTVKLKDLRGHISAVPQETVLFSGTIKENLKWGREDATDD 437
Query: 444 DVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEAL 503
+++ K IHDFI+ LP+GY++ G+ S G++Q +S+ARA++K P ++ILD+
Sbjct: 438 EIVEAAKIAQIHDFIISLPEGYDSRVERGGRNFSGGQKQRLSIARALVKKPKVLILDDCT 497
Query: 504 SSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR 563
SSVDP TE+ + + + + +G T+ II ++ ADK++V+ +G++ G+ ELL
Sbjct: 498 SSVDPITEKRILDGLKRYTKGCTTFIITQKIPTALLADKILVLHEGKVAGFGTHKELLEH 557
Query: 564 KGYFYKLYTSQ 574
+ ++Y SQ
Sbjct: 558 CKPYREIYESQ 568
>gb|AAB81307.1| (L47121) ATP-dependent translocator [Carnobacterium piscicola]
Length = 716
Score = 269 bits (680), Expect = 7e-71
Identities = 161/573 (28%), Positives = 304/573 (52%), Gaps = 7/573 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K + L F+ E+ + ++++ + + S Y + +D++I L
Sbjct: 144 KEKVDGLSSFLPIVWKEKTLVFNIILAALFITFFGIGSSYYFQGILDYFIPNQARSTLNI 203
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
++ ++ + + F +++ + GQ++ + + +L ++FF T+ +G+++S
Sbjct: 204 VSFGLIIVYLFRVLFEYSRSYLLVILGQRMSMAVMLRYFNHVLNLPMNFFATRKSGEIIS 263
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R + D N + D L S L I + + V + + + L L+T+ S+P ++ L F
Sbjct: 264 RFL-DANKIVDALASATLSVFLDIGMVLLVGVTLAIQNGTLFLITVASLPFYLVAILAFV 322
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+A ++ + A ++S + ES+ GIETI+A+ E+ V + + +K R +
Sbjct: 323 KSYEKANQDEMKAGATLNSSIIESLKGIETIKAYNGEEKVYNRVDQEFIQLMKKAFRTST 382
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
I + L+S +++ G Y G +S+G ++ + F P+ N++++
Sbjct: 383 LDNIQQGVKQGIQLISSGIILWIGSYYVMGGTISLGQLITYNALLVFFTDPLQNIINLQV 442
Query: 304 SLQSALAALERIYEIL----DDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVN 359
+Q+A A +R+ EI + + + + IS + + I F NV F Y LK+++
Sbjct: 443 KMQTAHVANKRLNEIFAIETEHKETDTEKIISKDTFQQGIIFDNVSFSYNINSSTLKNIS 502
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
PP SK+A+VG +G+GK+T+A L++ FY P++G I Y I+ I ++LR+ + YVP
Sbjct: 503 CVFPPRSKIALVGVSGSGKSTLAKLLVNFYPPSEGMICYGKINYLDIGYQNLRENVTYVP 562
Query: 420 QETYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
QE++ F GTI+EN+L + + E ++ +C + DFI K P +ET E LS
Sbjct: 563 QESFFFSGTILENLLFGLDYQPTFEQILDICHVTQLMDFISKQPLRFETILEEGASNLSG 622
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQ +++ARA+LK+ DI+ILDEA S +D E + +++L E +T I IAH L+I +
Sbjct: 623 GQRQRLAIARALLKNADILILDEATSGLDTLLEHAILENLLQLKE-KTIIFIAHHLAIAK 681
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLY 571
D+V+V+ +G++VE+G+ EL G + +L+
Sbjct: 682 ACDQVVVLHEGKLVEQGTHDELRYNNGMYQRLW 714
>gb|AAB40205.1| (U82664) multidrug resistance-like ATP-binding protein Mdl
[Escherichia coli]
Length = 631
Score = 268 bits (679), Expect = 9e-71
Identities = 170/570 (29%), Positives = 302/570 (52%), Gaps = 8/570 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
LKR + R+ L I V+ + +A A ++ P ++ ID+ + L +A L
Sbjct: 49 LKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPLLISYFIDNMVAKNNLP-LKVVAGLAA 107
Query: 70 LSLVAQWFFTTLQTFYTEVFGQK---VLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRII 126
+ Q F L + +F + V++ LR+ + + L+ L F T+ G ++SR+
Sbjct: 108 AYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVT 167
Query: 127 NDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKM 186
NDT V+ D+ V+ + L S + ++VAM LD ++ LV + P+++++ + +
Sbjct: 168 NDTEVIRDLYVTVVATVLRSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYS 227
Query: 187 RRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG 246
R R +A I+ E + G+ I+ F ++ + + S A ++ G
Sbjct: 228 TPIVRRVRAYLADINDGFNEIINGMSVIQQFRQQARFGERMGEASRSHYMARMQTLRLDG 287
Query: 247 -IFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 305
+ PL+++ S L + ++ G+ A G + +GV+ AFI Y R P+ + + L
Sbjct: 288 FLLRPLLSLFSSLILCGLLMLFGFSA-SGTIEVGVLYAFISYLGRLNEPLIELTTQQAML 346
Query: 306 QSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPA 365
Q A+ A ER++E++D + Y G IE NV F Y VLK++NL +P
Sbjct: 347 QQAVVAGERVFELMDGPR-QQYGNDDRPLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSR 405
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
+ VA+VG TG+GK+T+A+L+M +Y T+GEI DG +S +LR+ + V Q+ +
Sbjct: 406 NFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVL 465
Query: 426 PGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLIS 485
T + N+ + + EE V + + + + + + G T GE G LSVG++QL++
Sbjct: 466 ADTFLANVTLGR-DISEERVWQALETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLA 524
Query: 486 LARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIV 545
LAR +++ P I+ILDEA +S+D TEQ +Q+A+ + E T ++IAHRLS AD ++V
Sbjct: 525 LARVLVETPQILILDEATASIDSGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILV 584
Query: 546 VDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
+ G+ VE+G+ +LL+ +G ++++Y Q+
Sbjct: 585 LHRGQAVEQGTHQQLLAAQGRYWQMYQLQL 614
>sp|P75706|MDLB_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLB
>gi|7445961|pir||A64775 ABC-type transport protein mdlB
- Escherichia coli >gi|1786654|gb|AAC73552.1| (AE000151)
putative ATP-binding component of a transport system
[Escherichia coli K12]
Length = 593
Score = 268 bits (679), Expect = 9e-71
Identities = 170/570 (29%), Positives = 302/570 (52%), Gaps = 8/570 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
LKR + R+ L I V+ + +A A ++ P ++ ID+ + L +A L
Sbjct: 11 LKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPLLISYFIDNMVAKNNLP-LKVVAGLAA 69
Query: 70 LSLVAQWFFTTLQTFYTEVFGQK---VLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRII 126
+ Q F L + +F + V++ LR+ + + L+ L F T+ G ++SR+
Sbjct: 70 AYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVT 129
Query: 127 NDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKM 186
NDT V+ D+ V+ + L S + ++VAM LD ++ LV + P+++++ + +
Sbjct: 130 NDTEVIRDLYVTVVATVLRSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYS 189
Query: 187 RRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG 246
R R +A I+ E + G+ I+ F ++ + + S A ++ G
Sbjct: 190 TPIVRRVRAYLADINDGFNEIINGMSVIQQFRQQARFGERMGEASRSHYMARMQTLRLDG 249
Query: 247 -IFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 305
+ PL+++ S L + ++ G+ A G + +GV+ AFI Y R P+ + + L
Sbjct: 250 FLLRPLLSLFSSLILCGLLMLFGFSA-SGTIEVGVLYAFISYLGRLNEPLIELTTQQAML 308
Query: 306 QSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPA 365
Q A+ A ER++E++D + Y G IE NV F Y VLK++NL +P
Sbjct: 309 QQAVVAGERVFELMDGPR-QQYGNDDRPLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSR 367
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
+ VA+VG TG+GK+T+A+L+M +Y T+GEI DG +S +LR+ + V Q+ +
Sbjct: 368 NFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVL 427
Query: 426 PGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLIS 485
T + N+ + + EE V + + + + + + G T GE G LSVG++QL++
Sbjct: 428 ADTFLANVTLGR-DISEERVWQALETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLA 486
Query: 486 LARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIV 545
LAR +++ P I+ILDEA +S+D TEQ +Q+A+ + E T ++IAHRLS AD ++V
Sbjct: 487 LARVLVETPQILILDEATASIDSGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILV 546
Query: 546 VDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
+ G+ VE+G+ +LL+ +G ++++Y Q+
Sbjct: 547 LHRGQAVEQGTHQQLLAAQGRYWQMYQLQL 576
>gb|AAD55751.1|AF108385_1 (AF108385) transporter associated with antigen processing 2
[Heterodontus francisci]
Length = 724
Score = 268 bits (679), Expect = 9e-71
Identities = 165/568 (29%), Positives = 296/568 (52%), Gaps = 10/568 (1%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
+ +R + + + L+ V + + +A + PY + ID ++ RY F+ ++
Sbjct: 139 IARRLLTLSRPDLLPLSGAFVFLTLAVIAEMFLPYYMGKVID--LLGSRYDHQAFLIAIF 196
Query: 69 LLSLVAQWFFTT--LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRII 126
L+ + + + L+ ++ + +R+QL ++ + FF+ TGD+ SR+
Sbjct: 197 LMFVTSMGSSISAGLRGGLFMFTMSRLNKRVRNQLFTSVVHQEIGFFEATRTGDISSRLS 256
Query: 127 NDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKM 186
DT +++ + + L S++ G+++ M L +LTL+ PL ++I +
Sbjct: 257 TDTTLMSRSIGLNVNVFLRSLVKTVGMLIFMFSLSWQLTLLMFIESPLTIVIQKLYNKYH 316
Query: 187 RRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG 246
+ +E + IAK + + E ++ I T+R+F E + + + ET + + I
Sbjct: 317 MKLVQEVQDSIAKSNQLTGEIISAIRTVRSFATEDKESELYEEKLQETHELKNKRDIVRA 376
Query: 247 IFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQ 306
++ L I+++ G YL G +SIG +VAFI Y F G + +V +Y +
Sbjct: 377 VYLVCHRHIQLFMQIIMLYCGQYLIQTGQMSIGNLVAFILYQMNFGGYVRTLVHIYSEMT 436
Query: 307 SALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYI 362
++ A +++E LD + +G + E LKG + F+NV F Y RP VLK+V+ +
Sbjct: 437 HSVGAAAKVFEYLDRKPSVHTDGKLVAETLKGHVMFQNVSFSYPT-RPEIQVLKNVSFEL 495
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
A+VG +G GKTT +L+ RFY P G+IL DG ++ K ++G V QE
Sbjct: 496 KCGEITALVGPSGGGKTTCVSLLERFYQPQSGQILLDGKPIEEYEHKYYHNKLGLVGQEP 555
Query: 423 YLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
LF ++ +NI + + FI ++ GY T GEAG LS G++Q
Sbjct: 556 VLFALSVQDNICYGLQNCPMTAITAAAQRANARGFIERMEHGYNTDVGEAGGQLSAGQKQ 615
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
I++ARA+++ P I+ILDEA SS+D ++E +Q A+ + M G+T ++IAHRL ADK
Sbjct: 616 RIAIARALVRQPQILILDEATSSLDVESEHTIQQALSRDM-GKTILVIAHRLKTVEKADK 674
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKL 570
+IV+++G ++E+GS EL+ ++G +++L
Sbjct: 675 IIVIENGSVMEQGSHQELMQQEGCYFRL 702
>pir||S57913 probable translocation protein sppT, ATP-dependent - Lactobacillus
sake >gi|695620|emb|CAA88430.1| (Z48542) SppT
[Lactobacillus sakei]
Length = 718
Score = 268 bits (677), Expect = 2e-70
Identities = 158/573 (27%), Positives = 304/573 (52%), Gaps = 29/573 (5%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
F+ + ++R + + ++ + + ++ Y L+ ID YI L +A+ ++
Sbjct: 157 FVPTLMQQKRLVINITLAALLITIISILGSYFLQTVIDTYIPNNMQSTLAIVAIGLIIFY 216
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
Q FT Q F V GQ++ + + + + FF T+ TG+++SR ND N +
Sbjct: 217 GFQSIFTYAQNFLLAVLGQRLSIEIILSYLRHVFELPMSFFATRKTGEIISRF-NDANKI 275
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
D L S ++ I + + + +++ + L +TL +P+ + + F + ++
Sbjct: 276 IDALASAIISIFLDITVVVIMGIILIIQNTTLFWLTLAVIPIYIAVITLFAKPFEKLNQK 335
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKD------------VEKEFSKVSTETIKAYLR 240
+ A ++S + E + GIETI+A E + ++K F V +T++ ++
Sbjct: 336 EMESNAVLNSAIIEDLHGIETIKALTSESERYQKIDTAFVDYLKKSFDYVKADTLQQAIK 395
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
+ + +G+ + V+ G L +SIG ++ + F P+ N+++
Sbjct: 396 LFVQLGLN------------VFVLWVGAILVTHNELSIGQLMTYNALLAYFVNPLQNIIN 443
Query: 301 MYDSLQSALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDV 358
+ LQSA A R+ E+ +D E + S +L G IE +NV ++Y G+ VL+ +
Sbjct: 444 LQTKLQSARVANNRLNEVYLVDSEFKTERPIKSESQLVGPIELQNVSYQYGYGQRVLESI 503
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+L I P K+ IVG +G+GK+T+ L++ F++PT+G++L++ D + I +K+LR+ + Y+
Sbjct: 504 SLKIEPNEKLTIVGMSGSGKSTLVKLLVNFFEPTEGKVLFNQQDTQTIDKKTLRQFVNYI 563
Query: 419 PQETYLFPGTIMENILMAN-PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLS 477
Q Y+F G+I +N+ + N P + D++ C+ I + I K+P +ET E G LS
Sbjct: 564 AQTPYIFSGSIWDNLKLGNRPGITQADIMHACELAEIKNDIEKMPLQFETLLDEDGNTLS 623
Query: 478 VGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSIT 537
G++Q +++ARA+L ++I DE+ S +D TE L+ + ++ L E RT I IAHRL+I
Sbjct: 624 GGQKQRLTIARALLSPARVLIFDESTSGLDTITEGLLVDHLMAL-EERTIIFIAHRLAIA 682
Query: 538 RFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
+ + ++V+++G +VE G+ L+ +G +Y+L
Sbjct: 683 KKTNNILVLENGSVVETGTHDALVDTQGRYYQL 715
>pir||C49219 toxin apxIII secretion protein apxIIIB - Actinobacillus
pleuropneumoniae >gi|470686|gb|AAA21925.1| (L12145) RTX
toxin [Actinobacillus pleuropneumoniae 2]
Length = 711
Score = 267 bits (676), Expect = 2e-70
Identities = 165/566 (29%), Positives = 293/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ + L L +P +V +D ++ + L I + + +
Sbjct: 147 FIPAVIKYRKIFVETIIVSIFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVV 206
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + + L+T+ ++ L ++L +L + +F+ + GD V+R+ + + +
Sbjct: 207 IFEIVLSGLRTYIFSHSTSRIDVELGAKLFRHLLALPISYFENRRVGDTVARV-RELDQI 265
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLT+V L S+P + +++ +RR E
Sbjct: 266 RNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTIVILLSLPCYIAWSIFISPILRRRLDE 325
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV+ I+TI+A + + K + A RV + I +
Sbjct: 326 KFARNADNQSFLVESVSAIDTIKALAVTPQMTNIWDKQLASYVSADFRVTVLATIGQQGV 385
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++ F + + P+ + ++ Q ++
Sbjct: 386 QLIQKTVMIINLWLGAHLVISGDLSIGQLITFNMLSGQVIAPVVRLAQLWQDFQQVGISI 445
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E+Y+G +S+ ++ G+I F+++ F Y+ P+ L DVNL + + I
Sbjct: 446 TRLGDVLNSPT-ENYQGKLSLPEIFGDIAFKHIRFRYKPDAPIILDDVNLSVKQGEVIGI 504
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 505 VGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIR 564
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI + +P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 565 DNIALTDPSMSMERVIYAAKLAGAHDFISELREGYNTIVGELGAGLSGGQRQRIAIARAL 624
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M K+ GRT IIIAHRLS + AD++IV++ G
Sbjct: 625 VNNPRILIFDEATSALDYESEHIIMQNMQKICHGRTVIIIAHRLSTVKNADRIIVMEKGH 684
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G +LL + Y Y +Q+Q
Sbjct: 685 IVEQGKHNQLLENENGLY-YYLNQLQ 709
>sp|Q04473|RT3B_ACTPL RTX-III TOXIN DETERMINANT B (TOXIN RTX-III SECRETION ATP-BINDING
PROTEIN) (APX-IIIB) (CYTOLYSIN IIIB) (CLY-IIIB)
Length = 711
Score = 267 bits (676), Expect = 2e-70
Identities = 165/566 (29%), Positives = 293/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ + L L +P +V +D ++ + L I + + +
Sbjct: 147 FIPAVIKYRKIFVETIIVSIFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVV 206
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + + L+T+ ++ L ++L +L + +F+ + GD V+R+ + + +
Sbjct: 207 IFEIVLSGLRTYIFSHSTSRIDVELGAKLFRHLLALPISYFENRRVGDTVARV-RELDQI 265
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLT+V L S+P + +++ +RR E
Sbjct: 266 RNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTIVILLSLPCYIAWSIFISPILRRRLDE 325
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV+ I+TI+A + + K + A RV + I +
Sbjct: 326 KFARNADNQSFLVESVSAIDTIKALAVTPQMTNIWDKQLASYVSADFRVTVLATIGQQGV 385
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++ F + + P+ + ++ Q ++
Sbjct: 386 QLIQKTVMIINLWLGAHLVISGDLSIGQLITFNMLSGQVIAPVVRLAQLWQDFQQVGISI 445
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E+Y+G +S+ ++ G+I F+++ F Y+ P+ L DVNL + + I
Sbjct: 446 TRLGDVLNSPT-ENYQGKLSLPEIFGDIAFKHIRFRYKPDAPIILDDVNLSVKQGEVIGI 504
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 505 VGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIR 564
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI + +P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 565 DNIALTDPSMSMERVIYAAKLAGAHDFISELREGYNTIVGELGAGLSGGQRQRIAIARAL 624
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M K+ GRT IIIAHRLS + AD++IV++ G
Sbjct: 625 VNNPRILIFDEATSALDYESEHIIMQNMQKICHGRTVIIIAHRLSTVKNADRIIVMEKGH 684
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G +LL + Y Y +Q+Q
Sbjct: 685 IVEQGKHNQLLENENGLY-YYLNQLQ 709
>pir||A69829 ABC transporter (ATP-binding protein) homolog yheI - Bacillus
subtilis >gi|2226166|emb|CAA74450.1| (Y14080)
hypothetical protein [Bacillus subtilis]
>gi|2633306|emb|CAB12810.1| (Z99109) similar to ABC
transporter (ATP-binding protein) [Bacillus subtilis]
Length = 585
Score = 267 bits (676), Expect = 2e-70
Identities = 171/559 (30%), Positives = 299/559 (52%), Gaps = 8/559 (1%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTT 80
R T+AIV++ V + + P +L AID + G + G + + + ++ +
Sbjct: 18 RYTIAIVLLLAVN--VIEMFPPKLLGNAIDD-MKAGAFTAEGLLFYIGIFFVLTAAVYIM 74
Query: 81 LQTFYTEVFGQKVLRN--LRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVS 138
+ ++FG L LR++L +L + F++ TGDL++R ND V+
Sbjct: 75 SYFWMHQLFGGANLMEKILRTKLMGHLLTMSPPFYEKNRTGDLMARGTNDLQAVSLTTGF 134
Query: 139 GLLGGLGSILSLAGIIVAM-LLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKI 197
G+L + S + + I + M L+ KLT + +P+M I +G K+ + E +
Sbjct: 135 GILTLVDSTMFMMTIFLTMGFLISWKLTFAAIIPLPVMAIAISLYGSKIHERFTEAQNAF 194
Query: 198 AKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASL 257
++ V ESV+G+ IRA+ +E + + F++++ + + ++VA +F P + +
Sbjct: 195 GALNDRVLESVSGVRVIRAYVQETNDVRRFNEMTADVYQKNMKVAFIDSLFEPTVKLLVG 254
Query: 258 LSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYE 317
S ++ + YG +L ++ +++G +V+F Y P+ + + + +Q A+L+R+ E
Sbjct: 255 ASYLIGLGYGAFLVFRNELTLGELVSFNVYLGMMIWPMFAIGELINVMQRGNASLDRVNE 314
Query: 318 ILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAIVGKTG 375
L E +V D + + K G+I F +V F Y L+D++ + V I GKTG
Sbjct: 315 TLSYETDVTDPKQPADLKEPGDIVFSHVSFTYPSSTSDNLQDISFTVRKGQTVGIAGKTG 374
Query: 376 AGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILM 435
+GKTTI ++R Y P +G I + G+ ++I LR IGYVPQ+ LF T+ ENIL
Sbjct: 375 SGKTTIIKQLLRQYPPGEGSITFSGVPIQQIPLDRLRGWIGYVPQDHLLFSRTVKENILY 434
Query: 436 ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPD 495
+A +++V + E + LP G ET GE G LS G++Q IS+ARA++ +P+
Sbjct: 435 GKQDATDKEVQQAIAEAHFEKDLHMLPSGLETMVGEKGVALSGGQKQRISIARALMANPE 494
Query: 496 IVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEG 555
I+ILD++LS+VD KTE + + + +G+T+ I+ HRLS AD ++V+D G I E G
Sbjct: 495 ILILDDSLSAVDAKTEAAIIKNIRENRKGKTTFILTHRLSAVEHADLILVMDGGVIAERG 554
Query: 556 SPGELLSRKGYFYKLYTSQ 574
+ ELL+ G++ + Y Q
Sbjct: 555 THQELLANNGWYREQYERQ 573
>sp|P11599|HLYB_PROVU HEMOLYSIN SECRETION ATP-BINDING PROTEIN >gi|72492|pir||LEEBBV
hemolysin secretion protein hlyB - Proteus vulgaris
>gi|45904|emb|CAA31330.1| (X12852) HlyB haemolysin
secretion protein (AA 1 - 707) [Proteus vulgaris]
Length = 707
Score = 267 bits (675), Expect = 3e-70
Identities = 169/566 (29%), Positives = 293/566 (50%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ V L L +P +V +D ++ + L I + +
Sbjct: 143 FIPAVIKYRKIFIETLIVSVFLQLFALITPLFFQVVMDKVLVHRGFSTLNIITIALAVVA 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + + L+T+ ++ L ++L +L + +F+++ GD V+R+ + + +
Sbjct: 203 IFEITLSGLRTYIFTHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARV-RELDQI 261
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ L L + +L M KLTLV L S+P +++ +RR +
Sbjct: 262 RNFLTGQALTSILDLLFSFIFFAVMWYYSPKLTLVILFSLPCYATWSIFISPILRRRLDD 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + A +V + I +
Sbjct: 322 KFARNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLATIGQQGI 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +I+ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 382 QLIQKAVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVAPVIRLAQLWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E Y+G +++ ++ G+I FRN+ F Y+ P+ L ++NL I + I
Sbjct: 442 TRLGDVLNYPT-ESYQGKLTLPEINGDISFRNIRFRYKPDAPIILNNINLNIKQGEIIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ LI RFY P G++L DG D LR+++G V Q+ L +I+
Sbjct: 501 VGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSII 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +A+P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 561 DNIALADPGMPVEKVIHAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M K+ +GRT IIIAHRLS + AD++IV++ G+
Sbjct: 621 VNNPKILIFDEATSALDYESEHVIMRNMHKICQGRTVIIIAHRLSTVKNADRIIVMEKGQ 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
I+E+G ELLS Y Y Q+Q
Sbjct: 681 IIEQGKHKELLSDPESLYH-YLHQLQ 705
>gb|AAA25544.1| (M24197) leukotoxin (LktB) [Pasteurella haemolytica]
Length = 708
Score = 267 bits (675), Expect = 3e-70
Identities = 170/567 (29%), Positives = 294/567 (50%), Gaps = 7/567 (1%)
Query: 13 FIKEALSERRT-LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS 71
FI + R+ L ++VSI A L +P +V +D ++ + L I + +
Sbjct: 144 FIPAVIKYRKIFLETLIVSIFLQIFA-LITPLFFQVVMDKVLVHRGFSTLNIITVALAIV 202
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
++ + + L+T+ ++ L ++L +L + +F+ + GD V+R+ + +
Sbjct: 203 IIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENRRVGDTVARV-RELDQ 261
Query: 132 VNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
+ + L L + +L M KLTLV L S+P ++ +++ +RR
Sbjct: 262 IRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYILWSIFISPILRRRLD 321
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
E + A + + ESV I I+A + + K + RV + I
Sbjct: 322 EKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVFISFRVTVLATIGQQG 381
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ + +++ + G +L G +SIG ++AF + + P+ + ++ Q +
Sbjct: 382 VQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGIS 441
Query: 312 LERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVA 369
+ R+ ++L+ E Y+G +S+ ++KG+I F+N+ F Y+ P +L +VNL I +
Sbjct: 442 VTRLGDVLNSPT-EQYQGKLSLPEIKGDISFKNIRFRYKPDAPTILNNVNLEIRQGEVIG 500
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
IVG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 501 IVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSI 560
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI +++P E VI K G HDFI +L +GY T GE G LS G+RQ I++ARA
Sbjct: 561 RENIALSDPGMPMERVIYAAKLAGAHDFISELREGYTTIVGEQGAGLSGGQRQRIAIARA 620
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++ +P I+I DEA S++D ++E ++ M K+ +GRT I+IAHRLS + AD++IV++ G
Sbjct: 621 LVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHRLSTVKNADRIIVMEKG 680
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELL Y Y Q+Q
Sbjct: 681 EIVEQGKHHELLQNSNGLYS-YLHQLQ 706
>emb|CAA11805.1| (AJ224003) ATP-dependent transporter [Carnobacterium divergens]
Length = 724
Score = 267 bits (675), Expect = 3e-70
Identities = 167/569 (29%), Positives = 304/569 (53%), Gaps = 18/569 (3%)
Query: 11 KRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLL 70
K+F L +++ + I ++ + + +AS + L+ ID YI + I++ ++
Sbjct: 152 KKFFPLILEKKKLVVITFIAAIIVLIIQIASTFYLQKIIDVYIPQKMNGTITIISLGMII 211
Query: 71 SLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTN 130
+ Q F+ +Q Q + ++ + +L+ + FF T+ TG+++SR + ++
Sbjct: 212 IYIYQQIFSFIQINSMNQLSQSLTSDIVLTYIKHVLKLPMSFFSTRRTGEIISRFTDVSS 271
Query: 131 VVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTL--VTLTSVPLMVIIALYFGGKMRR 188
+V+ +S ++ + +S+ IIV+ LL + L + L S+P+ II + F ++
Sbjct: 272 IVD--AISSVIISIFLDMSMI-IIVSFFLLRQNMLLFCLILLSIPVYAIIIISFFRPFKK 328
Query: 189 AYRETRQKIAKISSVVEESVAGIETIRAFGKEKD----VEKEFSKVSTETIKAYLRVAIY 244
+ Q + +SS + E + GI TI++ G E + +E EF + K +
Sbjct: 329 LSTDAMQANSIMSSSIIEDLNGISTIKSLGVEDERFSKIESEFGDYLNKEFKNIQTRYVQ 388
Query: 245 MGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDS 304
M L + +L+ +VV+ G YL G V++G V+ F F P+ N++++
Sbjct: 389 MA----LKTVTNLILNVVVLWTGSYLVITGKVTLGQVITFSLLISYFLTPLENIINLQPK 444
Query: 305 LQSALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYI 362
LQ+A A R+ E+ ++ E + + + L G+I+ + + Y +L D+ L I
Sbjct: 445 LQAAKVAYNRLNEVYLVNGEEINKKKSYT-NNLLGDIQINKLSYSYGLNDEILSDITLQI 503
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
S +VG +G+GKTT+A L+++FYD GEIL +G K I +LR+ I Y+PQ+
Sbjct: 504 KMNSVTCLVGPSGSGKTTLAKLLVKFYDARHGEILLNGFSLKDIDIGTLRQFINYLPQDP 563
Query: 423 YLFPGTIMENILMANPEAKEEDVI-RVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
Y+F GTI++N+L+ E EED + V + I D I K+P G +TS +S G++
Sbjct: 564 YIFDGTILDNLLIGAKEKVEEDELWAVLDIVEIKDEIKKMPLGLQTSLSVENTTISGGQK 623
Query: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFAD 541
Q I+LAR +L D +++LDE S +D E+ + N ++ + + +T I IAHRL + + +D
Sbjct: 624 QRIALARTLLTDSKVLVLDEVTSQLDLLLERKIVNNLVNI-QHKTIIFIAHRLEVAKKSD 682
Query: 542 KVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
K+I + +G+++E+G EL+ RKG+FY L
Sbjct: 683 KIIALSEGKVIEQGEYKELIDRKGFFYSL 711
>gb|AAF23810.1|AF213822_25 (AF213822) inner membrane ABC transporter [Zymomonas mobilis]
Length = 565
Score = 267 bits (675), Expect = 3e-70
Identities = 168/511 (32%), Positives = 272/511 (52%), Gaps = 5/511 (0%)
Query: 68 YLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIN 127
Y ++V + FF + + V+ R +L E + + L + K GDL I
Sbjct: 56 YAATIVVEVFFRLKSMNFNYQYWPCVIGEQRIRLAEALYKMPLLQLREKDVGDLSE--IM 113
Query: 128 DTNVVNDV-LVSGLLGGLGSILSLAGII-VAMLLLDVKLTLVTLTSVPLMVIIALYFGGK 185
+NV+N +S L ++SL ++ VA+ L D ++ L+ S+ M+ I
Sbjct: 114 GSNVMNAANALSSLANIFVEVVSLPILLWVAITLFDYRMGLILAVSLIAMLPILYKIQAI 173
Query: 186 MRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYM 245
+ + + A+ +S + E V GI +A + V + +
Sbjct: 174 YNSSSADLDRADAESASRIIEYVKGIAVFKATSQAGAKSPRLEAVFHDQQEIQSHGNKSS 233
Query: 246 GIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 305
+ L L+++++IA+ GYLA K +++I VA + A P+N + ++
Sbjct: 234 ASYISLCQFIVQLALVILIAFAGYLAQKHSLNIPKTVALVIIAVHIIEPLNTIAAISKLF 293
Query: 306 QSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPA 365
+ A +L+RI IL+ + + + ++ + K +I F V FEY VL D++L +P
Sbjct: 294 EIAEISLQRIKNILNSKGLPQLQPQAIPQ-KFDINFNQVTFEYPDSPVVLHDIDLALPSE 352
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
S +VG +G GKTT+ LI RF DPTKGEI G+D + +++ L + V Q+ +LF
Sbjct: 353 SLTGVVGSSGCGKTTLVQLIARFADPTKGEIKIGGVDIRSLTQSQLSSLLSIVYQDVWLF 412
Query: 426 PGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLIS 485
TI NILM PEA EE++I + IHDFI LP+ Y+T GE G LS GERQ IS
Sbjct: 413 NDTIRANILMGRPEATEEELIHAAQSANIHDFICSLPQRYDTLVGEVGSSLSGGERQRIS 472
Query: 486 LARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIV 545
+ARA+LK+ I+ILDE +S+D ++E VQ A+ L++G+T I++AHRL+ ADK+IV
Sbjct: 473 IARAILKNTPIIILDEPTASLDSESEYAVQRAISSLIKGKTVIMVAHRLNTLTAADKIIV 532
Query: 546 VDDGRIVEEGSPGELLSRKGYFYKLYTSQMQ 576
+D G I+EEG +L+ K Y+Y ++ +Q++
Sbjct: 533 LDRGSIIEEGCHEDLIKNKSYYYNMWNTQLK 563
>gb|AAD21059.1| (AF119150) RtxB protein [Vibrio cholerae]
Length = 702
Score = 266 bits (673), Expect = 5e-70
Identities = 166/566 (29%), Positives = 297/566 (52%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLA-IVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS 71
FI E L +R L+ I++ S V LA L SP +V +D ++ + L + +++
Sbjct: 132 FIPEFLQHKRVLSEILLFSFVLQILA-LISPLFFQVVMDKVLVHQAWSTLDVLVFGLVIT 190
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
V + L+ + ++ L +L + + L FFK++ G +V+R+ + +
Sbjct: 191 GVIEVVLRGLREYQYAHTANRIDIQLGLKLVQHLFGLPLMFFKSRQVGAIVTRV-RELDT 249
Query: 132 VNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
+ + L + +L + + M LL LT + + +VP V++A + +M+ A
Sbjct: 250 IREFLTGSMFTLTVELLFMFVFLYVMSLLSAPLTGLFIATVPCYVLLAWWLTPRMQAAIE 309
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
+ A +S + E+VAG ET+++ E + + + + + + V L
Sbjct: 310 KQFSHAAANTSFLTETVAGSETLKSLAVEPRFIRRWDEQTEKMVTTGYDVQQLNNRSNHL 369
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ + ++ + ++ G ++IG ++AF P+ +V ++ A
Sbjct: 370 VQLLQKITSVAILWLGATEVLSLEMTIGQLIAFNMMTNHIAQPLARMVELWGQFIQTRVA 429
Query: 312 LERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKG-RPVLKDVNLYIPPASKVAI 370
+E++ ++L+ VE + G + G I F+N+ F Y+ P + D++L I + +
Sbjct: 430 IEKLGDMLNLP-VEQHTGSDNVTISGAISFKNILFRYQPDIPPTINDLSLDIRAGETLGV 488
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG +G+GK+T+A L++R Y P +G I DGI I+ + LR+R+G V QE +LF ++
Sbjct: 489 VGTSGSGKSTLARLLLRLYSPEQGSITIDGIPLNHINVQQLRQRVGVVLQENFLFHKSVS 548
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
ENI + PEA E++I K G HDFI+KLP GY+T E G+ LS G+RQ +++AR +
Sbjct: 549 ENIAQSKPEASLEEIIEAAKLSGAHDFILKLPMGYDTVLAEGGQSLSGGQRQRLAIARTL 608
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
L DP ++ILDEA S++D +++ ++Q M + GRT I IAHRLS R D++IV+ G
Sbjct: 609 LSDPKVLILDEATSALDDESQAVIQANMASIARGRTVITIAHRLSTVRDCDRIIVLHQGT 668
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+GS +LL+ + +L+ Q +
Sbjct: 669 IVEQGSHQQLLAYGKQYKQLWQLQQE 694
>pir||H82198 RTX toxin transporter VC1448 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655948|gb|AAF94605.1| (AE004223)
RTX toxin transporter [Vibrio cholerae]
Length = 720
Score = 266 bits (673), Expect = 5e-70
Identities = 166/566 (29%), Positives = 297/566 (52%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLA-IVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS 71
FI E L +R L+ I++ S V LA L SP +V +D ++ + L + +++
Sbjct: 150 FIPEFLQHKRVLSEILLFSFVLQILA-LISPLFFQVVMDKVLVHQAWSTLDVLVFGLVIT 208
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
V + L+ + ++ L +L + + L FFK++ G +V+R+ + +
Sbjct: 209 GVIEVVLRGLREYQYAHTANRIDIQLGLKLVQHLFGLPLMFFKSRQVGAIVTRV-RELDT 267
Query: 132 VNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
+ + L + +L + + M LL LT + + +VP V++A + +M+ A
Sbjct: 268 IREFLTGSMFTLTVELLFMFVFLYVMSLLSAPLTGLFIATVPCYVLLAWWLTPRMQAAIE 327
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
+ A +S + E+VAG ET+++ E + + + + + + V L
Sbjct: 328 KQFSHAAANTSFLTETVAGSETLKSLAVEPRFIRRWDEQTEKMVTTGYDVQQLNNRSNHL 387
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ + ++ + ++ G ++IG ++AF P+ +V ++ A
Sbjct: 388 VQLLQKITSVAILWLGATEVLSLEMTIGQLIAFNMMTNHIAQPLARMVELWGQFIQTRVA 447
Query: 312 LERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKG-RPVLKDVNLYIPPASKVAI 370
+E++ ++L+ VE + G + G I F+N+ F Y+ P + D++L I + +
Sbjct: 448 IEKLGDMLNLP-VEQHTGSDNVTISGAISFKNILFRYQPDIPPTINDLSLDIRAGETLGV 506
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG +G+GK+T+A L++R Y P +G I DGI I+ + LR+R+G V QE +LF ++
Sbjct: 507 VGTSGSGKSTLARLLLRLYSPEQGSITIDGIPLNHINVQQLRQRVGVVLQENFLFHKSVS 566
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
ENI + PEA E++I K G HDFI+KLP GY+T E G+ LS G+RQ +++AR +
Sbjct: 567 ENIAQSKPEASLEEIIEAAKLSGAHDFILKLPMGYDTVLAEGGQSLSGGQRQRLAIARTL 626
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
L DP ++ILDEA S++D +++ ++Q M + GRT I IAHRLS R D++IV+ G
Sbjct: 627 LSDPKVLILDEATSALDDESQAVIQANMASIARGRTVITIAHRLSTVRDCDRIIVLHQGT 686
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+GS +LL+ + +L+ Q +
Sbjct: 687 IVEQGSHQQLLAYGKQYKQLWQLQQE 712
>sp|P26760|RT1B_ACTPL RTX-I TOXIN DETERMINANT B (TOXIN RTX-I SECRETION ATP-BINDING
PROTEIN) (APX-IB) (HLY-IB) (CYTOLYSIN IB) (CLY-IB)
>gi|97137|pir||D43599 hemolysin I secretion protein
ApxIB - Actinobacillus pleuropneumoniae
>gi|38944|emb|CAA43425.1| (X61112) ClyI-B protein
[Actinobacillus pleuropneumoniae]
Length = 707
Score = 266 bits (672), Expect = 6e-70
Identities = 169/566 (29%), Positives = 291/566 (50%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ + + L +P +V +D ++ + L I + + +
Sbjct: 143 FIPAVIKYRKIFIETLIVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNVITVALAIVV 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + L+T+ ++ L ++L +L + +F+ + GD V+R+ +
Sbjct: 203 LFEIVLNGLRTYIFAHSTSRIDVELGARLFRHLLALPISYFENRRVGDTVARVRELDQIR 262
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L + S V M KLTLV L S+P + +++ +RR E
Sbjct: 263 NFLTGQALTSVLDLMFSFIFFAV-MWYYSPKLTLVILGSLPFYMGWSIFISPILRRRLDE 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + A RV I +
Sbjct: 322 KFARGADNQSFLVESVTAINTIKALAVTPQMTNTWDKQLASYVSAGFRVTTLATIGQQGV 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +++ + G +L G +SIG ++AF + + P+ + ++ Q ++
Sbjct: 382 QFIQKVVMVITLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E Y+G +++ ++KG+I FRN+ F Y+ PV L DVNL I + I
Sbjct: 442 TRLGDVLNSPT-ESYQGKLALPEIKGDITFRNIRFRYKPDAPVILNDVNLSIQQGEVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ LI RFY P G++L DG D LR+++G V Q+ L +I
Sbjct: 501 VGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIR 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +A+P E ++ K G H+FI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 561 DNIALADPGMPMEKIVHAAKLAGAHEFISELREGYNTIVGEQGAGLSGGQRQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M ++ +GRT IIIAHRLS + AD++IV++ G+
Sbjct: 621 VNNPKILIFDEATSALDYESEHIIMRNMHQICKGRTVIIIAHRLSTVKNADRIIVMEKGQ 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELL+ Y Y Q+Q
Sbjct: 681 IVEQGKHKELLADPNGLYH-YLHQLQ 705
>emb|CAA60043.1| (X86087) EHEC-hlyB [Escherichia coli]
Length = 706
Score = 266 bits (672), Expect = 6e-70
Identities = 169/566 (29%), Positives = 296/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + RR L V+ L +P +V +D ++ + L I + +++ +
Sbjct: 143 FIPSVVKYRRILLEVLTVSAFIQFLALITPLFFQVVMDKVLVHRGFSTLNIITIAFIIVI 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + T +T+ ++ L ++L +L + +F+ + G+ V+R+ +
Sbjct: 203 LFEVILTGARTYIFSHTTSRIDVELGAKLFRHLLALPVSYFENRRVGETVARVRELDQIR 262
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L S+ V M +LTLV L S+P VI +L+ +RR +
Sbjct: 263 NFLTGQALTSVLDLFFSVIFFCV-MWYYSPQLTLVILLSLPCYVIWSLFISPLLRRRLDD 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A+ + + E+V I TI++ + + K + + RV + +
Sbjct: 322 KFLRNAENQAFLVETVTAINTIKSMAVSPQMIATWDKQLAGYVASSFRVNLVAMTGQQGI 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +++ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 382 QLIQKSVMVISLWMGAHLVISGEISIGQLIAFNMLAGQVIAPVIRLAHLWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEGISV-EKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKVAI 370
ER+ ++L+ VE G ++ +++G+IEF+NV F Y G +L ++NLYI + I
Sbjct: 442 ERLGDVLNTP-VEKKSGRNILPEIQGDIEFKNVRFRYSSDGNVILNNINLYISKGDVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ L+ RFY P G+IL DG D + LR++IG V QE L +I+
Sbjct: 501 VGRSGSGKSTLTKLLQRFYIPETGQILIDGHDLSLADPEWLRRQIGVVLQENILLNRSII 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +A+P E I + G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 561 DNITLASPAVSMEQAIEAARLAGAHDFIRELKEGYNTIVGEQGVGLSGGQRQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M ++ + RT IIIAHRLS + A+++IV+D+G
Sbjct: 621 VTNPRILIFDEATSALDYESENIIMKNMSRICKNRTVIIIAHRLSTVKNANRIIVMDNGF 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
I E+G+ EL+S+K Y Y Q+Q
Sbjct: 681 ISEDGTHKELISKKDSLY-AYLYQLQ 705
>pir||T31072 heterocyst differentiation protein HetC - Anabaena sp
>gi|2828798|gb|AAC38130.1| (U55386) HetC [Anabaena
PCC7120]
Length = 1044
Score = 266 bits (672), Expect = 6e-70
Identities = 165/576 (28%), Positives = 298/576 (51%), Gaps = 5/576 (0%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
KS L R+ + + R L ++++ + + LA+P +V +D + L
Sbjct: 470 KSEKFSLGRYGQTLWNYRTVLRQIILASLLVQVFGLATPLFTQVILDQVMPIKNLPNLHI 529
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
A +L + + T + F ++ +L LQ L FF ++ D++S
Sbjct: 530 FAFSFLCLGIWRTVLTAQHQNLLDYFANRIDLSLIGGFINYTLQLPLQFFASRQVDDIIS 589
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ + + + +G IL + + M +LTL+ L+ + +VI+ +
Sbjct: 590 RV-QENRKIQLFISRRAIGAAVDILMVMTYLGLMTYYSWQLTLLVLSWIIPVVILTVVAS 648
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+++A RE Q+ A+ S + E + G+ T++ E+ ++K + + + +K LR
Sbjct: 649 PYLKQASREIFQESARQHSSMVEIMTGVATVKTATAERPLQKYWEERFLKMLKVRLRGQK 708
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
+ + + +V+ +G L G +S+G VAF P+ ++V ++D
Sbjct: 709 LAHRLQVTRTLINHVGSTLVLWFGATLVMGGKMSLGQFVAFNMLTGNVTHPVLSLVGLWD 768
Query: 304 SLQSALAALERIYEILD--DENVEDYEGISVEKLKGEIEFRNVWFEYE--KGRPVLKDVN 359
Q L ++ER+ ++ E + + ++GE+ F NV F Y + R L++++
Sbjct: 769 EFQEILISVERLNDVYAAVPEASSQTTLLVMPPIRGEVRFENVSFRYNSFQERNALQNIS 828
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
I P + I+G++G+GK+T+ANL+ Y P G IL DG D +S +SLR ++G V
Sbjct: 829 FGIKPQQTIGIIGQSGSGKSTLANLLAGLYRPDTGRILIDGHDMAGVSPQSLRSQVGLVA 888
Query: 420 QETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
Q+++LF GTI+ENI + + E I K G HDFI LP GY+T GE G +LS G
Sbjct: 889 QDSFLFSGTILENITLHDQELSLIQAIAAAKLTGAHDFIQALPLGYDTQVGERGFMLSGG 948
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
+RQ I++ARA++++P I+ILDEA S +D ++E+ Q + ++ + RT+ I++HRLS R+
Sbjct: 949 QRQKIAIARALVRNPKILILDEATSGLDAESERRFQQNLAQISQERTTFIVSHRLSTVRY 1008
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
AD + V+D G ++E G+ EL++ G ++ L Q+
Sbjct: 1009 ADHIFVIDQGMVIEHGTHQELMAIAGLYHHLAQLQL 1044
>gi|10955284 Hemolysin B [Escherichia coli] >gi|7442681|pir||T00228 hemolysin B
- Escherichia coli plasmid pO157 >gi|7442682|pir||T42149
hemolysin transport protein - Escherichia coli plasmid
pO157 >gi|3337016|dbj|BAA31775.1| (AB011549) Hemolysin B
[Escherichia coli] >gi|3822163|gb|AAC70117.1| (AF074613)
hemolysin transport protein [Escherichia coli O157:H7]
Length = 706
Score = 266 bits (672), Expect = 6e-70
Identities = 169/566 (29%), Positives = 296/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + RR L V+ L +P +V +D ++ + L I + +++ +
Sbjct: 143 FIPSVVKYRRILLEVLTVSAFIQFLALITPLFFQVVMDKVLVHRGFSTLNIITIAFIIVI 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + T +T+ ++ L ++L +L + +F+ + G+ V+R+ +
Sbjct: 203 LFEVILTGARTYIFSHTTSRIDVELGAKLFRHLLALPVSYFENRRVGETVARVRELEQIR 262
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L S+ V M +LTLV L S+P VI +L+ +RR +
Sbjct: 263 NFLTGQALTSVLDLFFSVIFFCV-MWYYSPQLTLVILLSLPCYVIWSLFISPLLRRRLDD 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A+ + + E+V I TI++ + + K + + RV + +
Sbjct: 322 KFLRNAENQAFLVETVTAINTIKSMAVSPQMIATWDKQLAGYVASSFRVNLVAMTGQQGI 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +++ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 382 QLIQKSVMVISLWMGAHLVISGEISIGQLIAFNMLAGQVIAPVIRLAHLWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEGISV-EKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKVAI 370
ER+ ++L+ VE G ++ +++G+IEF+NV F Y G +L ++NLYI + I
Sbjct: 442 ERLGDVLNTP-VEKKSGRNILPEIQGDIEFKNVRFRYSSDGNVILNNINLYISKGDVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ L+ RFY P G+IL DG D + LR++IG V QE L +I+
Sbjct: 501 VGRSGSGKSTLTKLLQRFYIPETGQILIDGHDLSLADPEWLRRQIGVVLQENILLNRSII 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +A+P E I + G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 561 DNITLASPAVSMEQAIEAARLAGAHDFIRELKEGYNTIVGEQGVGLSGGQRQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M ++ + RT IIIAHRLS + A+++IV+D+G
Sbjct: 621 VTNPRILIFDEATSALDYESENIIMKNMSRICKNRTVIIIAHRLSTVKNANRIIVMDNGF 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
I E+G+ EL+S+K Y Y Q+Q
Sbjct: 681 ISEDGTHKELISKKDSLY-AYLYQLQ 705
>dbj|BAA93709.1| (AB032930) hemolysin B [Escherichia coli]
Length = 705
Score = 266 bits (672), Expect = 6e-70
Identities = 169/566 (29%), Positives = 296/566 (51%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + RR L V+ L +P +V +D ++ + L I + +++ +
Sbjct: 142 FIPSVVKYRRILLEVLTVSAFIQFLALITPLFFQVVMDKVLVHRGFSTLNIITIAFIIVI 201
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + T +T+ ++ L ++L +L + +F+ + G+ V+R+ +
Sbjct: 202 LFEVILTGARTYIFSHTTSRIDVELGAKLFRHLLALPVSYFENRRVGETVARVRELEQIR 261
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L S+ V M +LTLV L S+P VI +L+ +RR +
Sbjct: 262 NFLTGQALTSVLDLFFSVIFFCV-MWYYSPQLTLVILLSLPCYVIWSLFISPLLRRRLDD 320
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A+ + + E+V I TI++ + + K + + RV + +
Sbjct: 321 KFLRNAENQAFLVETVTAINTIKSMAVSPQMIATWDKQLAGYVASSFRVNLVAMTGQQGI 380
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +++ + G +L G +SIG ++AF A + P+ + ++ Q ++
Sbjct: 381 QLIQKSVMVISLWMGAHLVISGEISIGQLIAFNMLAGQVIAPVIRLAHLWQDFQQVGISV 440
Query: 313 ERIYEILDDENVEDYEGISV-EKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKVAI 370
ER+ ++L+ VE G ++ +++G+IEF+NV F Y G +L ++NLYI + I
Sbjct: 441 ERLGDVLNTP-VEKKSGRNILPEIQGDIEFKNVRFRYSSDGNVILNNINLYISKGDVIGI 499
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ L+ RFY P G+IL DG D + LR++IG V QE L +I+
Sbjct: 500 VGRSGSGKSTLTKLLQRFYIPETGQILIDGHDLSLADPEWLRRQIGVVLQENILLNRSII 559
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +A+P E I + G HDFI +L +GY T GE G LS G+RQ I++ARA+
Sbjct: 560 DNITLASPAVSMEQAIEAARLAGAHDFITELKEGYNTIVGEQGVGLSGGQRQRIAIARAL 619
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M ++ + RT IIIAHRLS + A+++IV+D+G
Sbjct: 620 VTNPRILIFDEATSALDYESENIIMKNMSRICKNRTVIIIAHRLSTVKNANRIIVMDNGF 679
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
I E+G+ EL+S+K Y Y Q+Q
Sbjct: 680 ISEDGTHKELISKKDSLY-AYLYQLQ 704
>pir||T06165 multidrug resistance protein 1 homolog - barley
>gi|2292907|emb|CAA71179.1| (Y10099) P-glycoprotein
homologue [Hordeum vulgare]
Length = 1232
Score = 265 bits (671), Expect = 8e-70
Identities = 168/524 (32%), Positives = 301/524 (57%), Gaps = 19/524 (3%)
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTK--ST 118
L F+ + + + +VA +++ + ++ + +R E IL+ + FF ++ +T
Sbjct: 86 LNFVYLAFAILVVA-----SMEGYCWSRTSERQVLRIRHLYLEAILRQEVAFFDSQEATT 140
Query: 119 GDLVSRIINDTNVVNDVLVSGL-LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
++++ I D +++ +VL + L + S + ++G+ + +L LV+ V L++I
Sbjct: 141 SEIINSISKDASLIQEVLSEKVPLFLMHSTVFVSGLAFSTYF-SWRLALVSYPLVLLLII 199
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
L +G + RE+R++ AK +S+VE+++ I+T+ +F EK + + ++ + +TI
Sbjct: 200 PGLIYGKYLLYLSRESRREYAKANSLVEQALGSIKTVYSFTAEKGIIQRYTAILDKTINL 259
Query: 238 YLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVV----VAFIQYAQRFRG 293
++ I G+ ++ + + YG L S G + ++F+
Sbjct: 260 GIKQGIAKGLAVGFTGLSFAIWAFLAW-YGSRLVMYHHESGGRIYAAGISFVLGGLSLGM 318
Query: 294 PINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP 353
+ + ++ +A LERI + N +D +G+ +++++GEIEF ++ F Y RP
Sbjct: 319 ALPELKHFIEASVAATRILERINRV-PQINDDDPKGLVLDQVRGEIEFESIRFVYPS-RP 376
Query: 354 ---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
VLKD NL IP +A+VG +G+GK+T L+ RFYD ++G + DGID KK++ KS
Sbjct: 377 NMTVLKDFNLQIPAGQTIALVGSSGSGKSTAIALVQRFYDASEGTVKVDGIDIKKLNLKS 436
Query: 411 LRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAG 470
+R +IG V Q+ LF +I ENIL P+A + + H+FIM LP+GYET G
Sbjct: 437 IRSKIGLVSQDHALFGTSIKENILFGKPDATMDLLYAAAMTANAHNFIMGLPEGYETKIG 496
Query: 471 EAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
E G LLS G++Q I++ARA+LK+P I++LDEA S++D ++E+LVQ+A+ + GRT++++
Sbjct: 497 ERGALLSGGQKQRIAIARAVLKNPAILLLDEATSALDSESEKLVQHALDQASMGRTTLVV 556
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
AH+LS + AD++ VVD GRI E G+ EL+++ G + +L Q
Sbjct: 557 AHKLSTVKNADQIAVVDGGRIAEIGTHDELINKGGPYSRLVKLQ 600
Score = 247 bits (624), Expect = 3e-64
Identities = 161/510 (31%), Positives = 277/510 (53%), Gaps = 23/510 (4%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFK--TKSTGDLVSRIINDTNVVNDVLVS 138
LQ + G+ ++R +R Q+ EKIL +F T S+G L SR+ +++++V LV+
Sbjct: 729 LQHYNFAYMGEHLVRRIRVQVLEKILTFEAAWFDEDTNSSGSLCSRLSDESSLVK-TLVA 787
Query: 139 GLLGGLGSILSLAGIIVAM---LLLDVKLTLVTLTSVPLMVIIALYFGGK--MRRAYRET 193
+ L + + GI++A+ L++ KL LV + P +I Y+ K + R+
Sbjct: 788 DRISLL--LQTACGIVIAVTMGLIVAWKLALVMIAVQPCTMIC--YYAKKIVLSNVSRDL 843
Query: 194 RQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMN 253
+ + + + E+V + +FG + + F E ++ + + GI L
Sbjct: 844 AKAQYESTQIAIEAVYNHRMVTSFGCSSKILQLFEHTQEEPLRKARKKSWVAGITTGLSP 903
Query: 254 IASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALE 313
+ LS + YGG LA G +S G V I + SM L A+
Sbjct: 904 CLTFLSWALDFWYGGKLAQSGEISAGDVFKTFFVLVSTGKLIADAGSMTSDLAKGANAVA 963
Query: 314 RIYEILDDENVEDYEGISVEK------LKGEIEFRNVWFEYEKGRP---VLKDVNLYIPP 364
++E+LD +++ + VEK ++G IEF+ V F Y RP +L+D +L +
Sbjct: 964 SVFEVLDRKSISP-QNSQVEKDNPKSKIQGRIEFKKVDFSYPT-RPQCLILQDFSLDVKA 1021
Query: 365 ASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYL 424
+ + +VG++G GK+TI LI RFYD +G + DG+D ++++ R V QE +
Sbjct: 1022 GTSIGLVGRSGCGKSTIIGLIQRFYDVDRGAVRIDGVDVREMNVLWYRGFTALVSQEPAM 1081
Query: 425 FPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLI 484
F G++ +NI PEA EE+++ K H+FI L GY+T GE G LS G++Q I
Sbjct: 1082 FSGSVRDNIAFGKPEADEEEIVEAAKAANAHEFISSLKDGYDTDCGEHGIQLSGGQKQRI 1141
Query: 485 SLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVI 544
++ARA++++P I++LDEA S++D ++EQ+VQ A+ ++M GRT+II+AHRL+ + AD +
Sbjct: 1142 AIARAIIRNPAILLLDEATSALDAQSEQVVQEALDRIMTGRTTIIVAHRLNTIKNADSIA 1201
Query: 545 VVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+ +G+++E G+ +L+++KG F+ L T Q
Sbjct: 1202 FLGEGKVIERGTYPQLMNKKGAFFNLATLQ 1231
>emb|CAA08835.1| (AJ009799) ABC transporter protein [Gallus gallus]
Length = 1288
Score = 265 bits (671), Expect = 8e-70
Identities = 177/518 (34%), Positives = 279/518 (53%), Gaps = 23/518 (4%)
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
LVA + T+ F+T G++V + +R + I++ + +F G+L +R+I+D +
Sbjct: 134 LVAAYIQTS---FWTLAAGRQV-KKIREKFFHAIMRQEIGWFDVNDAGELNTRLIDDVSK 189
Query: 132 VNDVLVSGLLGGLGSILS-----LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKM 186
+N+ G+ +G ++ L G IV + KLTLV L P++ + A + K+
Sbjct: 190 INE----GIGDKIGFLIQSETTFLTGFIVGFIR-GWKLTLVILAVSPVLGLSAALWA-KI 243
Query: 187 RRAYRETRQKI-AKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYM 245
A+ + Q AK +V EE ++ + T+ AFG ++ K + K + + +R AI
Sbjct: 244 LTAFTDKEQAAYAKAGAVAEEVLSAVRTVIAFGGQEKEIKRYHKNLEDAKRIGIRKAITS 303
Query: 246 GIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 305
I + S + YG L SIG V+ I ++
Sbjct: 304 NISMGAAFLLIYASYALAFWYGTTLILANEYSIGNVLTVFFSVLIGAFSIGQTAPSIEAF 363
Query: 306 QSALAALERIYEILDDE-NVEDYE--GISVEKLKGEIEFRNVWFEYEKGRP---VLKDVN 359
+A A I+ I+D+E ++ Y G + +KG +EF+NV+F Y RP +LK +N
Sbjct: 364 ANARGAAYAIFNIIDNEPEIDSYSDAGHKPDHIKGNLEFQNVFFNYPS-RPDVEILKGLN 422
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
L + VA+VG +G GK+T LI RFYDP +G I DG D K ++ + LR+ IG V
Sbjct: 423 LKVNCGQTVALVGGSGCGKSTTVQLIQRFYDPKEGTITIDGQDLKSLNVRYLREIIGVVN 482
Query: 420 QETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
QE LF TI ENI + E++ R KE +DFIMKLPK +ET GE G +S G
Sbjct: 483 QEPVLFATTIAENIRYGREDVTMEEIERATKEANAYDFIMKLPKKFETVVGERGAQMSGG 542
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
++Q I++ARA++ +P I++LDEA S++D ++E +VQ A+ K EGRT++++AHRLS R
Sbjct: 543 QKQRIAIARALVHNPKILLLDEATSALDTESESVVQAALDKAREGRTTVVVAHRLSTVRN 602
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
AD + V + G I E+G+ +L+ +KG +YKL Q E
Sbjct: 603 ADLIAVFESGVITEQGNHSQLIEKKGIYYKLVNMQTIE 640
Score = 242 bits (612), Expect = 6e-63
Identities = 153/520 (29%), Positives = 268/520 (51%), Gaps = 11/520 (2%)
Query: 65 AMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGDLV 122
++L+L + +F +Q F G+ + LR + +L+ ++ +F STG L
Sbjct: 764 SLLFLALGIISFFTFFVQGFAFGKAGEILTMKLRFMAFKAMLRQDMAWFDDPKNSTGALT 823
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+R+ ND + V L +I +L I+ L+ +LTL+ L VP++ + +
Sbjct: 824 TRLANDASQVKGATGVRLALIAQNIANLGTGIIISLVYGWQLTLLLLAVVPIIAVAGMIE 883
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
+ ++ + ++ + E++ I T+ + +EK E + + + ++ A
Sbjct: 884 MKMLAGHAKKDKIELEAAGKIATEAIENIRTVASLTREKRFELMYGEHLLVPYRNSVKKA 943
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAV---SIGVVVAFIQYAQRFRGPINNVV 299
G + L + +G YL G + ++ +V + + + G ++
Sbjct: 944 HIFGFCFSLSQAMMFFTYAGCFRFGAYLVVNGHIEYKTVFLVFSAVVFGAMALGQTSSFA 1003
Query: 300 SMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLK 356
Y + + A L ++ + + +G EK G ++V F Y RP +L+
Sbjct: 1004 PDYAKAKISAAHLFVLFNRVPPIDSYREDGEKPEKFGGNTRIKDVKFNYPN-RPEVKILQ 1062
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
+NL + +A+VG +G GK+T+ L+ RFYDP GEI++D ID K ++ + LR IG
Sbjct: 1063 GLNLAVEKGETLALVGSSGCGKSTVVQLLERFYDPLSGEIVFDDIDAKTLNIQWLRSHIG 1122
Query: 417 YVPQETYLFPGTIMENILMANP--EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGK 474
V QE LF TI ENI + E E++I K IH FI LP+ Y T G+ G
Sbjct: 1123 IVSQEPILFDFTIAENIAYGDNSREVSHEEIISAAKAASIHSFIDSLPEKYNTRVGDKGT 1182
Query: 475 LLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRL 534
LS G++Q I++ARA+++ P I++LDEA S++D ++E++VQ A+ K EGRT I+IAHRL
Sbjct: 1183 QLSGGQKQRIAIARALIRKPQILLLDEATSALDTESEKIVQEALDKAREGRTCIVIAHRL 1242
Query: 535 SITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
S + ADK+ V+ +G+++E+G+ +LL+ KG++Y L Q
Sbjct: 1243 STIQNADKIAVIQNGKVIEQGTHQQLLAEKGFYYSLVNVQ 1282
>pir||C81352 lipid export ABC transport protein Cj0803 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968249|emb|CAB73068.1| (AL139076) lipid export ABC
transport protein [Campylobacter jejuni]
Length = 580
Score = 265 bits (671), Expect = 8e-70
Identities = 171/555 (30%), Positives = 292/555 (51%), Gaps = 6/555 (1%)
Query: 22 RTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTL 81
+ AI + ++ ++ S Y L +++ + L + L +L + T L
Sbjct: 23 KQFAIAIFGMILASGGTAGSFYALEPILNYIFVEKNEALLYTVPFLLVLMYFFKNLGTYL 82
Query: 82 QTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLL 141
Q+FY G +LR LR+++ + +L+ ++DFFK +G+LVSR ND N + ++ + +
Sbjct: 83 QSFYVSFIGTDMLRVLRARVLKNVLRLDMDFFKRYRSGELVSRCTNDINALQSIVSNIIP 142
Query: 142 GGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKIS 201
+L+ G++ +L L L +PL + ++F K+++ R ++ + +
Sbjct: 143 DFFRELLTAIGLLAVVLYQSPTLAFFALVILPLAIFPLVWFAKKLKKYARNIQETNSDLL 202
Query: 202 SVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVI 261
S + E + IE I+A EK +F+K + K L+ A + PLM++ + V
Sbjct: 203 SYLGEIFSNIELIKANDNEKKESDKFAKHNDTLCKLNLKSARIDALTSPLMDMMGSVGVA 262
Query: 262 VVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD 321
VVI GG G++S+G ++F+ P+ + S+Y LQ A+AA ER + +LD
Sbjct: 263 VVIIVGGREVINGSMSVGSFISFVSALFAIYTPLKRLSSLYGKLQGAVAASERTFYLLDL 322
Query: 322 ENVEDYEGISVE-KLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKVAIVGKTGAGKT 379
E +G S E K +I F NV F YE + VLK VN +A+VG +G GK+
Sbjct: 323 E--PQIKGGSKELKNIEKISFENVEFAYENPHKSVLKGVNFDFVKGQMLALVGTSGGGKS 380
Query: 380 TIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPE 439
+I NL+M FY+ KG+IL + D + +SL +IG V Q YLF + NI + E
Sbjct: 381 SIINLLMYFYEKQKGKILLNQEDISTFTIESLHAKIGLVTQNIYLFNDSFAANIAYSE-E 439
Query: 440 AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVIL 499
+EE VI+ K ++F+ ++ G E GK LS G++Q I++ARA+ K+PD++I
Sbjct: 440 LEEEKVIQALKLANAYEFVKEM-GGIWAEVKEHGKNLSGGQKQRIAIARALYKNPDVLIF 498
Query: 500 DEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGE 559
DEA S++D ++E+ + + L + R +++AHRLS ADK++V+D G+++ G E
Sbjct: 499 DEATSALDNESEKAIVKTIENLKQDRLILVVAHRLSTIENADKIVVLDKGKVLAIGKDEE 558
Query: 560 LLSRKGYFYKLYTSQ 574
LL + K + +
Sbjct: 559 LLQTCSLYQKFKSKE 573
>pir||E70435 ABC transporter (MsbA subfamily) - Aquifex aeolicus
>gi|2983916|gb|AAC07466.1| (AE000745) ABC transporter
(MsbA subfamily) [Aquifex aeolicus]
Length = 554
Score = 265 bits (670), Expect = 1e-69
Identities = 165/539 (30%), Positives = 306/539 (56%), Gaps = 19/539 (3%)
Query: 24 LAIVVVSIVGSALAN---LASPYILRVAIDHYIIPGRYKEL-GFIAMLYLLSLVAQWFFT 79
+ + ++S++GS + + A +++ +D+ +I +EL ++ +L+ +L+ Q F
Sbjct: 15 ILLFLLSLLGSLIQSSGATALALLVKQVVDNVLILKNQEELLKYVLLLFSSALIIQVGFF 74
Query: 80 TLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSG 139
+ +F +KV+ +LR++++EK+L + +++ +G+L+SRI++D + V
Sbjct: 75 -ISSFTLSYISEKVIYSLRNEIYEKLLYAPINYVLYTPSGELISRIVSDLEQLRQVFADY 133
Query: 140 LLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAK 199
+ L L + + +L D+ LTL+ L P+M + YF K ++ R+K+A
Sbjct: 134 IPKLLREPLVVLALFGVLLYRDLFLTLLILLLFPVMALFTKYFSEKKKKHLSRQREKVAL 193
Query: 200 ISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLS 259
++S++ E++ G E I+ F E K+F ++S ++ +++ +Y+ + ++N +
Sbjct: 194 LTSILSETLRGFENIKLFLAENRFIKDFKELSFRIFRSSVKINLYV-VGNTVINYTFGYA 252
Query: 260 VIVVIAY-GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEI 318
V+ +I + GGY KG ++ G ++F+ + P+ +L+ + ERI +
Sbjct: 253 VVSLILFAGGYRIVKGDITTGDFISFLTALFMIQKPLMETQKAIMNLRGSAPIFERIRNL 312
Query: 319 L----DDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKT 374
L + + E++EG LK IEFR+V + + + +LK+VNL + SKV I G T
Sbjct: 313 LNVPEEKDGSEEFEG-----LKERIEFRDVSVKINR-KEILKNVNLSVYRGSKVGIKGHT 366
Query: 375 GAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENIL 434
G+GK+T LI R + +GEI D + ++ KSLR++IG++ QE +F G++ EN+L
Sbjct: 367 GSGKSTFVKLIPRLLE-YEGEIFVDHTELREFKLKSLREKIGFLSQEVMVFRGSVRENLL 425
Query: 435 MANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDP 494
+A P+A EE++++ EL DF++ P+G + E GK LS GE+Q ++LAR LK+P
Sbjct: 426 IAKPDATEEEMLKAL-ELAKCDFVLNSPEGLDKFLEEGGKNLSGGEKQRLALARIFLKNP 484
Query: 495 DIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVE 553
+IVILDEA S++DPKTE+ V + K ++ +T +AHR I F D ++ + GR+ E
Sbjct: 485 EIVILDEATSALDPKTEEEVIYNLYKFLKEKTIFAVAHRPFIFNFCDVILEFEGGRLKE 543
>pir||E82561 toxin secretion ABC transporter ATP-binding protein XF2397
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9107580|gb|AAF85196.1|AE004049_1 (AE004049) toxin
secretion ABC transporter ATP-binding protein [Xylella
fastidiosa]
Length = 720
Score = 264 bits (667), Expect = 2e-69
Identities = 171/564 (30%), Positives = 289/564 (50%), Gaps = 3/564 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ LA V + + L +P +V +D ++ L I + +
Sbjct: 154 FIPAVVKYRKLLAEVFAVSLFIQIFALVTPLFYQVVMDKVLVHQALSTLEVIVVGLISLA 213
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + TTL+T K+ L ++L +L L +F+++ GD ++R+ N+
Sbjct: 214 LFEVLLTTLRTHVFAHTTSKIDVELGARLFRHLLALPLAYFESRRVGDTIARVRELENIR 273
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
+ + L L + ++ + V M LTL+ + S+PL +I+ + +R+ E
Sbjct: 274 HFLTGQALTSVLDLLFTVVFLSV-MFWYSSWLTLIVVISLPLYALISAFITPVLRKRLDE 332
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A + + E+V+GI T++A + V + + + A V + +
Sbjct: 333 KFARGADNQAFLVETVSGIGTVKAMAVDPRVTRTWDNQLAGYVGASFSVTKIATLGQQSV 392
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ L+ + V+ +G L G +S+G ++AF + + PI + ++ Q ++
Sbjct: 393 QLVQKLTNVAVLFWGAKLVIDGQLSLGQLIAFNMLSGQVTAPIIRLAQLWQDFQQVGLSV 452
Query: 313 ERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVAIV 371
ER+ EIL+ +++ ++G I F + F Y P VL ++L I P + IV
Sbjct: 453 ERLGEILNTRTELPGSRMTLPPIQGRITFERLIFRYRPDTPDVLAGIDLDIQPGEVIGIV 512
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G++G+GK+T+ L+ R Y P +G +L D D LR++IG V QE +LF ++ E
Sbjct: 513 GRSGSGKSTLTKLVQRMYVPERGRVLVDSHDLSLADPAWLRRQIGVVLQENFLFNRSVRE 572
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI MA+P E VI G H FI +LP+GY+T GE G LS G+RQ I++ARA++
Sbjct: 573 NIAMADPGIPLERVIHAATLAGAHPFIAELPEGYDTKIGEHGTGLSGGQRQRIAIARALI 632
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
DP I+I DEA S++D ++E V M + +GRT +IIAHRLS R AD+++V+D G+I
Sbjct: 633 GDPRILIFDEATSALDYESEHAVMQNMRAICKGRTVLIIAHRLSTVRNADRIVVIDKGKI 692
Query: 552 VEEGSPGELLSR-KGYFYKLYTSQ 574
VE GS LL+R G++ LY Q
Sbjct: 693 VESGSHETLLNRNNGHYAHLYRLQ 716
>pir||T04251 P-glycoprotein 2 - Arabidopsis thaliana >gi|2108252|emb|CAA71277.1|
(Y10228) P-glycoprotein-2 [Arabidopsis thaliana]
>gi|2108254|emb|CAA71276.1| (Y10227) P-glycoprotein-2
[Arabidopsis thaliana] >gi|4538925|emb|CAB39661.1|
(AL049483) P-glycoprotein-2 (pgp2) [Arabidopsis thaliana]
>gi|7269447|emb|CAB79451.1| (AL161564) P-glycoprotein-2
(pgp2) [Arabidopsis thaliana]
Length = 1233
Score = 263 bits (666), Expect = 3e-69
Identities = 170/538 (31%), Positives = 292/538 (53%), Gaps = 28/538 (5%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--K 116
KE+ IA+L+ + V T++ G+++ +R + IL++ + +F
Sbjct: 707 KEIKKIAILFCCASVITLIVYTIEHICFGTMGERLTLRVRENMFRAILKNEIGWFDEVDN 766
Query: 117 STGDLVSRIINDTNVVNDVLVSG---LLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVP 173
++ L SR+ +D ++ ++V LL LG +++ I+A +L + +LTLV L + P
Sbjct: 767 TSSMLASRLESDATLLKTIVVDRSTILLQNLGLVVT--SFIIAFIL-NWRLTLVVLATYP 823
Query: 174 LMV-------IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKE 226
L++ + +GG + +AY K + + ESV+ I T+ AF E+ + +
Sbjct: 824 LVISGHISEKLFMQGYGGDLNKAY-------LKANMLAGESVSNIRTVAAFCAEEKILEL 876
Query: 227 FSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQ 286
+S+ E K+ R G+F+ + S + + YG L KG V+
Sbjct: 877 YSRELLEPSKSSFRRGQIAGLFYGVSQFFIFSSYGLALWYGSTLMDKGLAGFKSVMKTFM 936
Query: 287 YAQRFRGPINNVVSMYDSLQSALAALERIYEILDDEN-VEDYEGISVEKLKGEIEFRNVW 345
+ +++ L + ++EILD + + + ++G IE + V
Sbjct: 937 VLIVTALAMGETLALAPDLLKGNQMVASVFEILDRKTQIVGETSEELNNVEGTIELKGVH 996
Query: 346 FEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGID 402
F Y RP + +D +L + +A+VG++G+GK+++ +LI+RFYDPT G+++ +G D
Sbjct: 997 FSYPS-RPDVVIFRDFDLIVRAGKSMALVGQSGSGKSSVISLILRFYDPTAGKVMIEGKD 1055
Query: 403 GKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLP 462
KK+ K+LRK IG V QE LF TI ENIL N A + +V+ H FI LP
Sbjct: 1056 IKKLDLKALRKHIGLVQQEPALFATTIYENILYGNEGASQSEVVESAMLANAHSFITSLP 1115
Query: 463 KGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLM 522
+GY T GE G +S G+RQ I++ARA+LK+P I++LDEA S++D ++E++VQ A+ +LM
Sbjct: 1116 EGYSTKVGERGVQMSGGQRQRIAIARAILKNPAILLLDEATSALDVESERVVQQALDRLM 1175
Query: 523 EGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGEL-LSRKGYFYKLYTSQMQEVP 579
RT++++AHRLS + AD + V+ G+IVE+GS +L L++ G ++KL + Q Q+ P
Sbjct: 1176 ANRTTVVVAHRLSTIKNADTISVLHGGKIVEQGSHRKLVLNKSGPYFKLISLQQQQQP 1233
Score = 224 bits (565), Expect = 2e-57
Identities = 154/490 (31%), Positives = 256/490 (51%), Gaps = 28/490 (5%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKTK-STGDLVSRIINDTNVVNDVLVSGLLGGLGSIL 148
G++ +R +L ++ F T+ STG+++S I +D VV D L S +G +
Sbjct: 108 GERQAAKMRRAYLRSMLSQDISLFDTEASTGEVISAITSDILVVQDAL-SEKVGNFLHYI 166
Query: 149 S--LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEE 206
S +AG + + +++LVTL+ VPL+ + + R+ K + EE
Sbjct: 167 SRFIAGFAIGFTSV-WQISLVTLSIVPLIALAGGIYAFVAIGLIARVRKSYIKAGEIAEE 225
Query: 207 SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAY 266
+ + T++AF E+ + + + T K + + G+ M+ LS +++ +
Sbjct: 226 VIGNVRTVQAFTGEERAVRLYREALENTYKYGRKAGLTKGLGLGSMHCVLFLSWALLVWF 285
Query: 267 GGYLAYKGAVSIG--------VVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEI 318
+ +K G VV+A + Q + A AA I+++
Sbjct: 286 TSVVVHKDIADGGKSFTTMLNVVIAGLSLGQ--------AAPDISAFVRAKAAAYPIFKM 337
Query: 319 LDDENVEDYE---GISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVG 372
++ V G + K+ G I+F++ F Y RP + +NL IP VA+VG
Sbjct: 338 IERNTVTKTSAKSGRKLGKVDGHIQFKDATFSYPS-RPDVVIFDRLNLAIPAGKIVALVG 396
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMEN 432
+G+GK+T+ +LI RFY+P G +L DG + ++ K LR +IG V QE LF TI EN
Sbjct: 397 GSGSGKSTVISLIERFYEPISGAVLLDGNNISELDIKWLRGQIGLVNQEPALFATTIREN 456
Query: 433 ILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLK 492
IL +A E++ R K FI LP+G+ET GE G LS G++Q I+++RA++K
Sbjct: 457 ILYGKDDATAEEITRAAKLSEAISFINNLPEGFETQVGERGIQLSGGQKQRIAISRAIVK 516
Query: 493 DPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIV 552
+P I++LDEA S++D ++E+ VQ A+ ++M GRT++++AHRLS R AD + VV +G+IV
Sbjct: 517 NPSILLLDEATSALDAESEKSVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVHEGKIV 576
Query: 553 EEGSPGELLS 562
E G+ L+S
Sbjct: 577 EFGNHENLIS 586
>gb|AAA75000.1| (U17608) multidrug resistance protein [Xenopus laevis]
>gi|1098061|prf||2115220A P-glycoprotein [Xenopus
laevis]
Length = 1287
Score = 263 bits (665), Expect = 4e-69
Identities = 170/525 (32%), Positives = 270/525 (51%), Gaps = 15/525 (2%)
Query: 58 YKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS 117
Y LGF ML ++ W + + ++ +RS +L+ + +F
Sbjct: 128 YSGLGFGVMLCAYIQISFWTLSA----------GRQIKKIRSNFFHAVLRQEIGWFDIND 177
Query: 118 TGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
G+L +R+ +D + +N+ + + L S+ +L + + KLT V P+M +
Sbjct: 178 AGELNTRLTDDVSKINEGIGDKIAMLLQSLTTLVTGFIIGFIKGWKLTWVMGAISPIMGL 237
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
A + + + + AK +V EE ++ I T+ AFG + + K + K
Sbjct: 238 SAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQNKEIHRYEKNLEDAKKI 297
Query: 238 YLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINN 297
++ AI + + + + YG L G +IG V+ +
Sbjct: 298 GIKKAITANVSIGFAFLMIYAAYSLAFWYGTTLIIDGGYTIGSVLTVFFAVIIGAFAVGQ 357
Query: 298 VVSMYDSLQSALAALERIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEY--EKGR 352
++ +A A I+ I+D++ D EG+ +K+KG+IEF+NV F Y K
Sbjct: 358 TSPNIEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGDIEFKNVIFTYPSRKDI 417
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VLK +NL IP VA+VG +G GK+T LI RFYDP G I DG D + ++ + LR
Sbjct: 418 QVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEDGVITLDGQDIRSLNIRYLR 477
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEA 472
+ IG V QE LF TI +NI + +E++ R KE +DFIMKLP ET GE
Sbjct: 478 EIIGVVSQEPILFDTTIADNIRYGREDVTKEEIERATKEANAYDFIMKLPDKLETLVGER 537
Query: 473 GKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAH 532
G LS G++Q I++ARA++++P I++LDEA S++D ++E +VQ+A+ K EGRT+I++AH
Sbjct: 538 GTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQSALDKAREGRTTIVVAH 597
Query: 533 RLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
RLS R A+ + D+G IVE+GS EL+ R G ++ L T Q E
Sbjct: 598 RLSTIRNANAIAGFDNGVIVEQGSHKELMERGGVYFNLVTLQTVE 642
Score = 217 bits (547), Expect = 3e-55
Identities = 149/521 (28%), Positives = 264/521 (50%), Gaps = 13/521 (2%)
Query: 67 LYLLSLVAQWFFTT-LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLVS 123
L L+L F T LQ F G+ + LR + +L+ + +F STG L +
Sbjct: 765 LLFLALGGVSFITFFLQGFTFGKAGEILTMRLRLGSFKSMLRQEIGWFDDSKNSTGALTT 824
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ D + V + L ++ +L I+ + +LTL+ L VP++ L
Sbjct: 825 RLATDASQVQGATGTRLALLAQNVANLGTAIIISFIYGWQLTLLILAIVPVIAAAGLVEM 884
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
++ ++++ K + ++V I T+ + +E+ E + K + ++ A
Sbjct: 885 KMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKSLEGPYRNSIKKAH 944
Query: 244 YMGIFWPLMNIASLLSVIVVIAY-GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
G+ + L +L + V + G YL +G + + V + S
Sbjct: 945 LHGLTYGLSQAHHVLCLCWVFSVLGAYLVVEGLMKLDEVFLVSSAIVLGAMALGQTSSFA 1004
Query: 303 DSLQSALAALERIYEILDD-ENVEDY--EGISVEKLKGEIEFRNVWFEYEKGRP---VLK 356
A+ + I+ +L+ ++ Y +G + G + F+ V F Y RP VL+
Sbjct: 1005 PDYTKAMISAAHIFSLLERVPQIDSYSDQGEKPKNCSGNVVFKGVNFNYPT-RPDITVLQ 1063
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
+++ + +A+VG +G GK+T +L+ RFYDP +GE+L DG+ + ++ + +R ++G
Sbjct: 1064 GLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFEGEVLVDGLSVRNLNIQWVRAQMG 1123
Query: 417 YVPQETYLFPGTIMENILMA--NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGK 474
V QE LF +I +NI N + +E++ KE IH FI L Y T G+ G
Sbjct: 1124 IVSQEPILFDCSIGDNIAYGDNNRKVTQEEIETAAKEANIHSFIESLTDKYNTRVGDKGT 1183
Query: 475 LLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRL 534
LS G++Q I++ARA+++ P I++LDEA S++D ++E++VQ A+ K GRT I+IAHRL
Sbjct: 1184 QLSGGQKQRIAIARALIRKPKILLLDEATSALDTESEKVVQEALDKARMGRTCIVIAHRL 1243
Query: 535 SITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
S + ADK+ V+ +G++VE+G+ +LL KG ++ L T Q+
Sbjct: 1244 STIQNADKIAVIQNGKVVEQGTHQQLLQLKGVYFSLVTIQL 1284
>pir||S55692 multidrug resistance protein homolog (mdr) - African clawed frog
Length = 1287
Score = 263 bits (665), Expect = 4e-69
Identities = 170/525 (32%), Positives = 270/525 (51%), Gaps = 15/525 (2%)
Query: 58 YKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS 117
Y LGF ML ++ W + + ++ +RS +L+ + +F
Sbjct: 128 YSGLGFGVMLCAYIQISFWTLSA----------GRQIKKIRSNFFHAVLRQEIGWFDIND 177
Query: 118 TGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
G+L +R+ +D + +N+ + + L S+ +L + + KLT V P+M +
Sbjct: 178 AGELNTRLTDDVSKINEGIGDKIAMLLQSLTTLVTGFIIGFIKGWKLTWVMGAISPIMGL 237
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
A + + + + AK +V EE ++ I T+ AFG + + K + K
Sbjct: 238 SAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQNKEIHRYEKNLEDAKKI 297
Query: 238 YLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINN 297
++ AI + + + + YG L G +IG V+ +
Sbjct: 298 GIKKAITANVSIGFAFLMIYAAYSLAFWYGTTLIIDGGYTIGSVLTVFFAVIIGAFAVGQ 357
Query: 298 VVSMYDSLQSALAALERIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEY--EKGR 352
++ +A A I+ I+D++ D EG+ +K+KG+IEF+NV F Y K
Sbjct: 358 TSPNIEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGDIEFKNVIFTYPSRKDI 417
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VLK +NL IP VA+VG +G GK+T LI RFYDP G I DG D + ++ + LR
Sbjct: 418 QVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEDGVITLDGQDIRSLNIRYLR 477
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEA 472
+ IG V QE LF TI +NI + +E++ R KE +DFIMKLP ET GE
Sbjct: 478 EIIGVVSQEPILFDTTIADNIRYGREDVTKEEIERATKEANAYDFIMKLPDKLETLVGER 537
Query: 473 GKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAH 532
G LS G++Q I++ARA++++P I++LDEA S++D ++E +VQ+A+ K EGRT+I++AH
Sbjct: 538 GTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQSALDKAREGRTTIVVAH 597
Query: 533 RLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
RLS R A+ + D+G IVE+GS EL+ R G ++ L T Q E
Sbjct: 598 RLSTIRNANAIAGFDNGVIVEQGSHKELMERGGVYFNLVTLQTVE 642
Score = 217 bits (548), Expect = 2e-55
Identities = 149/521 (28%), Positives = 264/521 (50%), Gaps = 13/521 (2%)
Query: 67 LYLLSLVAQWFFTT-LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLVS 123
L L+L F T LQ F G+ + LR + +L+ + +F STG L +
Sbjct: 765 LLFLALGGVSFITFFLQRFTFGKAGEILTMRLRLGSFKSMLRQEIGWFDDSKNSTGALTT 824
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ D + V + L ++ +L I+ + +LTL+ L VP++ L
Sbjct: 825 RLATDASQVQGATGTRLALLAQNVANLGTAIIISFIYGWQLTLLILAIVPVIAAAGLVEM 884
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
++ ++++ K + ++V I T+ + +E+ E + K + ++ A
Sbjct: 885 KMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKSLEGPYRNSIKKAH 944
Query: 244 YMGIFWPLMNIASLLSVIVVIAY-GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
G+ + L +L + V + G YL +G + + V + S
Sbjct: 945 LHGLTYGLSQAHHVLCLCWVFSVLGAYLVVEGLMKLDEVFLVSSAIVLGAMALGQTSSFA 1004
Query: 303 DSLQSALAALERIYEILDD-ENVEDY--EGISVEKLKGEIEFRNVWFEYEKGRP---VLK 356
A+ + I+ +L+ ++ Y +G + G + F+ V F Y RP VL+
Sbjct: 1005 PDYTKAMISAAHIFSLLERVPQIDSYSDQGEKPKNCSGNVVFKGVNFNYPT-RPDITVLQ 1063
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
+++ + +A+VG +G GK+T +L+ RFYDP +GE+L DG+ + ++ + +R ++G
Sbjct: 1064 GLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFEGEVLVDGLSVRNLNIQWVRAQMG 1123
Query: 417 YVPQETYLFPGTIMENILMA--NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGK 474
V QE LF +I +NI N + +E++ KE IH FI L Y T G+ G
Sbjct: 1124 IVSQEPILFDCSIGDNIAYGDNNRKVTQEEIETAAKEANIHSFIESLTDKYNTRVGDKGT 1183
Query: 475 LLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRL 534
LS G++Q I++ARA+++ P I++LDEA S++D ++E++VQ A+ K GRT I+IAHRL
Sbjct: 1184 QLSGGQKQRIAIARALIRKPKILLLDEATSALDTESEKVVQEALDKARMGRTCIVIAHRL 1243
Query: 535 SITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
S + ADK+ V+ +G++VE+G+ +LL KG ++ L T Q+
Sbjct: 1244 STIQNADKIAVIQNGKVVEQGTHQQLLQLKGVYFSLVTIQL 1284
>pir||F82198 probable toxin secretion transporter VC1446 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655946|gb|AAF94603.1| (AE004223) toxin secretion
transporter, putative [Vibrio cholerae]
Length = 721
Score = 263 bits (664), Expect = 5e-69
Identities = 163/570 (28%), Positives = 290/570 (50%), Gaps = 3/570 (0%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L F L ++ L V + + + L SP + ID ++ L +A+ L
Sbjct: 153 LSWFAPSILRQKSQLRDVFLYAIALQIFALVSPMLFENVIDKVLVGRSLSSLHVLALAML 212
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
+A+ ++ L+ +V L +L+ ++ L +FK + TG +++R+ +
Sbjct: 213 ALAIAEPAYSYLRNTVFGHLASQVNAELSGRLYRHLVGLPLTYFKQRQTGQIIARV-REM 271
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
+ L L L ++ + + M LT + + S+ + ++ L G +R+
Sbjct: 272 AQIRQFLTGSTLMLLLDLIFVTVFLAVMFHYASTLTWLVIGSLVIYFVLWLIAGPLIRKK 331
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
+ A ++ + E+V GIETI+ E +++ ++ ++ + I
Sbjct: 332 VESEYESDANATTFLTEAVTGIETIKTTATEHRFLEQWQRILSQQLNRSFDAQKSGLIAG 391
Query: 250 PLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSAL 309
+ + L+ +++ +G KG ++ G +VAF A P+ + ++ Q L
Sbjct: 392 QAIALVQKLTAALLLWWGVSAVLKGEITPGQLVAFNMLAGHVTQPVLRLAQIWQDFQHTL 451
Query: 310 AALERIYEILDDENVEDYEGI-SVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASK 367
AL R+ +ILD+ +G+ SV +L G IEF N+ F Y + P VL +++L I P
Sbjct: 452 IALRRVGDILDEPRENSKQGLASVPELDGGIEFSNIRFRYHQDAPEVLANLSLKIKPGQF 511
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
+ + G +G+GK+T+ L+ R Y P G++L DG+D SLR+ + V QE+ LF G
Sbjct: 512 IGVTGPSGSGKSTLTRLLQRLYVPQHGQVLVDGMDLAIADPVSLRRNMSVVLQESILFSG 571
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
++ +NI + P+A +E++ + G FI LP G+ GE G LS G+RQ I+LA
Sbjct: 572 SVADNIRLCKPQASDEEIRHAAQLAGALAFIEGLPHGFNQPVGEKGAALSGGQRQRIALA 631
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
RA+L +P I++LDEA S++D +E + + M ++ GRT I IAHRL+ R AD + V+D
Sbjct: 632 RALLVNPRILLLDEATSALDYNSEASIMSNMDEICRGRTVISIAHRLNTIRHADNIFVLD 691
Query: 548 DGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
G++ E G+ ELL+++G + KL+T Q+ E
Sbjct: 692 KGQVAESGTHEELLAQQGLYAKLWTQQVGE 721
>gb|AAD10836.1| (U52079) P-glycoprotein [Solanum tuberosum]
Length = 1313
Score = 262 bits (663), Expect = 7e-69
Identities = 177/569 (31%), Positives = 298/569 (52%), Gaps = 24/569 (4%)
Query: 26 IVVVSIVGSALANLASPYILRVAIDHYIIPGRY--------KELGFIAMLYLLSLVAQWF 77
++++ +G+ + + P LR D G Y +E+ A +L+ A W
Sbjct: 69 LMIIGSLGAFVHGCSLPLFLRFFADLVNSFGSYANDVDKMTQEVLKYAFYFLVVGAAIWA 128
Query: 78 FTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTK-STGDLVSRIINDTNVVNDVL 136
+ + G++ +R + E L ++ +F T+ T D+VS I D VV D
Sbjct: 129 SSWAEISCWMWTGERQTTKMRIKYLEAALNQDIQYFDTEVRTSDVVSAINTDAVVVQDA- 187
Query: 137 VSGLLGGLGSILS--LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
+S LG ++ L+G +V + +L LVTL VPL+ +I + + +++
Sbjct: 188 ISEKLGNFIHYMATFLSGFVVGFTAV-WQLALVTLAVVPLIAVIGAIYTVTSAKLSSQSQ 246
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
+ ++K ++VE++V I T+ F E + ++ + K + G+
Sbjct: 247 EALSKAGNIVEQTVVQIRTVLVFVGEAKALQAYTAALRVSQKIGYKSGFSKGLGLGATYF 306
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRG-PINNVVSMYDSLQSALAALE 313
+++ YGGYL + G+ +A + +A G + + A A
Sbjct: 307 TVFCCYALLLWYGGYLVRHHFTNGGLAIATM-FAVMIGGLALGQSAPSMTAFAKARVAAA 365
Query: 314 RIYEILDDENVEDYE---GISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASK 367
+I+ I+D + D G+ ++ + G++E +NV F Y RP +L + NL +P
Sbjct: 366 KIFRIIDHKPSVDRNAKTGLELDTVSGQLELKNVEFSYPS-RPEIKILNNFNLVVPAGKT 424
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
+A+VG +G+GK+T+ +LI RFYDPT G+++ DG D K + K LR++IG V QE LF
Sbjct: 425 IALVGSSGSGKSTVVSLIERFYDPTSGQLMLDGNDIKTLKLKWLRQQIGLVSQEPALFAT 484
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
+I ENIL+ P+A + ++ + H F++KLP G++T GE G LS G++Q I++A
Sbjct: 485 SIKENILLGRPDATQIEIEEAARVANAHSFVIKLPDGFDTQVGERGLQLSGGQKQRIAIA 544
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
RAMLK+P I++LDEA S++D ++E+LVQ A+ + M GRT+++IAHRLS R AD V V+
Sbjct: 545 RAMLKNPAILLLDEATSALDSESEKLVQEALDRFMIGRTTLVIAHRLSTIRKADLVAVLQ 604
Query: 548 DGRIVEEGSPGELLSR--KGYFYKLYTSQ 574
G + E GS EL+S+ G + KL Q
Sbjct: 605 QGSVSEIGSHDELMSKGENGMYAKLIKMQ 633
Score = 230 bits (580), Expect = 4e-59
Identities = 163/566 (28%), Positives = 281/566 (48%), Gaps = 22/566 (3%)
Query: 28 VVSIVGSALANLASP---YILRVAIDHYIIPGR-YKELGFIAMLYLLSLV--AQWFFTTL 81
++ +GS + S Y+L + Y P Y YLL V A F TL
Sbjct: 726 LIGSIGSVICGSLSAFFAYVLSAVLSVYYNPDHAYMSEQIAKYCYLLIGVSSAALIFNTL 785
Query: 82 QTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLVSRIINDTNVVNDVLVSG 139
Q +Y +V G+ + + +R ++ +L+ + +F + + + +R+ D N V +
Sbjct: 786 QHYYWDVVGENLTKRVREKMLAAVLKMEMAWFDQEENDSSRIAARLSLDANNVRSAIGDR 845
Query: 140 LLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAK 199
+ + + + A +L +L LV + P++V + M+ + AK
Sbjct: 846 ISVIMQNSALMLVACTAGFVLQWRLALVLIGVFPVVVAATVLQKMFMKGFSGDLEAAHAK 905
Query: 200 ISSVVEESVAGIETIRAFGKEKDVEKEF-SKVSTETIKAYLRVAIYMGIFWPLMNIASLL 258
+ + E+VA + T+ AF E + F S + T + + + I G + +
Sbjct: 906 ATQLAGEAVANVRTVAAFNSETKIVNLFDSSLQTPLRRCFWKGQI-AGSGYGIAQFLLYS 964
Query: 259 SVIVVIAYGGYLAYKGAVSIGVVV-AFIQYAQRFRGPINNVVSMYDSLQSALAALERIYE 317
S + + Y +L G + F+ G + D ++ A+ ++E
Sbjct: 965 SYALGLWYASWLVKHGISDFSKTIRVFMVLMVSANGAAETLTLAPDFIKGG-RAMRSVFE 1023
Query: 318 ILD---DENVEDYEGISV-EKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAI 370
+LD + +D + +V ++L+GE+EF++V F Y RP + +D+NL +A+
Sbjct: 1024 LLDRKTEVEPDDPDATAVPDRLRGEVEFKHVDFSYPT-RPDVSIFRDLNLRARAGKTLAL 1082
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG +G GK+++ +LI RFY+P+ G ++ DG D +K + KSLR+ I VPQE LF TI
Sbjct: 1083 VGPSGCGKSSVISLIERFYEPSSGRVIIDGKDIRKYNLKSLRRHIAVVPQEPCLFATTIY 1142
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
ENI + A E ++ H FI LP GY+T GE G LS G++Q I++ARA
Sbjct: 1143 ENIAYGHESATEAEITEAATLANAHKFISALPDGYKTFVGERGVQLSGGQKQRIAIARAF 1202
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
L+ ++++LDEA S++D ++E+ VQ A+ + G+T+I++AHRLS R A + V+DDG+
Sbjct: 1203 LRKAELMLLDEATSALDAESERCVQEALDRACAGKTTIVVAHRLSTIRNAHVIAVIDDGK 1262
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
+ E+GS LL K Y +Y +Q
Sbjct: 1263 VAEQGSHSHLL--KNYSDGIYARMIQ 1286
>dbj|BAB02855.1| (AB026644) multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1225
Score = 262 bits (663), Expect = 7e-69
Identities = 164/514 (31%), Positives = 278/514 (53%), Gaps = 24/514 (4%)
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFK--TKSTGDL 121
+A++Y+ A W ++ + G++ +R + + +L+ ++ +F ST D+
Sbjct: 70 VALVYVAC--ASWVICFIEGYCWTRTGERQAAKMREKYLKAVLRQDVGYFDLHVTSTSDV 127
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALY 181
++ + +D+ V+ D L L L + + + LL +LT+V + L++I L
Sbjct: 128 ITSVSSDSLVIQDFLSEKLPNFLMNTSAFVASYIVGFLLLWRLTIVGFPFIILLLIPGLM 187
Query: 182 FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRV 241
+G + R + R++ + S+ E+ ++ + T+ AFG EK + ++FS ++K LR
Sbjct: 188 YGRALIRISMKIREEYNEAGSIAEQVISSVRTVYAFGSEKKMIEKFSTALQGSVKLGLRQ 247
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSI------GVVVAFIQYAQRFRGP- 294
+ GI ++ S + A G+L + G+ + G V+ + F G
Sbjct: 248 GLAKGI--------AIGSNGITYAIWGFLTWYGSRMVMNHGSKGGTVSSVIVCVTFGGTS 299
Query: 295 INNVVSMYDSLQSALAALERIYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKG 351
+ +S A ERI ++++ + ++ EG +EK +GE+EF +V F Y
Sbjct: 300 LGQSLSNLKYFSEAFVVGERIMKVINRVPGIDSDNLEGQILEKTRGEVEFNHVKFTYPSR 359
Query: 352 --RPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRK 409
P+ D+ L +P VA+VG +G+GK+T+ +L+ RFYDP GEIL DG+ K+ K
Sbjct: 360 PETPIFDDLCLRVPSGKTVALVGGSGSGKSTVISLLQRFYDPIAGEILIDGLPINKLQVK 419
Query: 410 SLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSA 469
LR ++G V QE LF +I ENIL +A ++V+ K H FI + P Y+T
Sbjct: 420 WLRSQMGLVSQEPVLFATSIKENILFGKEDASMDEVVEAAKASNAHSFISQFPNSYQTQV 479
Query: 470 GEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSII 529
GE G LS G++Q I++ARA++K P I++LDEA S++D ++E++VQ A+ GRT+I+
Sbjct: 480 GERGVQLSGGQKQRIAIARAIIKSPIILLLDEATSALDSESERVVQEALDNASIGRTTIV 539
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR 563
IAHRLS R AD + VV +GRI+E GS ELL +
Sbjct: 540 IAHRLSTIRNADVICVVHNGRIIETGSHEELLEK 573
Score = 234 bits (591), Expect = 2e-60
Identities = 182/596 (30%), Positives = 301/596 (49%), Gaps = 27/596 (4%)
Query: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASP---YILRVAIDHYIIPG- 56
++ K SL+ F + R + +G+AL P Y + Y +
Sbjct: 631 LSPKDGKSLVPSFKRLMSMNRPEWKHALYGCLGAALFGAVQPIYSYSSGSMVSVYFLASH 690
Query: 57 -RYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVF-GQKVLRNLRSQLHEKILQSNLDFFK 114
+ KE I +L + L F + + Y + G+ + + +R ++ KIL +++F
Sbjct: 691 DQIKEKTRIYVLLFVGLALFTFLSNISQHYGFAYMGEYLTKRIRERMLGKILTFEVNWFD 750
Query: 115 T--KSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAM-LLLDVKLTLVTLTS 171
S+G + SR+ D N+V LV + L +S I A+ L++ + ++V ++
Sbjct: 751 KDENSSGAICSRLAKDANMVRS-LVGDRMSLLVQTISAVSITCAIGLVISWRFSIVMMSV 809
Query: 172 VPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVS 231
P++V+ ++ R + + S + E+V+ I TI AF ++ + V
Sbjct: 810 QPVIVVCFYTQRVLLKSMSRNAIKGQDESSKLAAEAVSNIRTITAFSSQERIINLLKMVQ 869
Query: 232 TETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIA--YGGYLAYKGAV-SIGVVVAFIQYA 288
K R + GI L SL++ + + YGG L G + S + F+ +A
Sbjct: 870 EGPRKDSARQSWLAGIM--LGTSQSLITCVSALNFWYGGKLIADGKMMSKEFLEIFLIFA 927
Query: 289 QRFRGPINNVVSMYDSLQSALAALERIYEILDDENV---EDYEGISVEKLKGEIEFRNVW 345
R I +M L A+ ++ +LD E+ +G +K+KG+I F NV
Sbjct: 928 STGR-VIAEAGTMTKDLVKGSDAVASVFAVLDRNTTIEPENPDGYVPKKVKGQISFSNVD 986
Query: 346 FEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGID 402
F Y RP + ++ ++ I AIVG +G+GK+TI +LI RFYDP KG + DG D
Sbjct: 987 FAYPT-RPDVIIFQNFSIDIEDGKSTAIVGPSGSGKSTIISLIERFYDPLKGIVKIDGRD 1045
Query: 403 GKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAK--EEDVIRVCKELGIHDFIMK 460
+ +SLR+ I V QE LF GTI ENI+ K E ++I K HDFI
Sbjct: 1046 IRSCHLRSLRQHIALVSQEPTLFAGTIRENIMYGGASNKIDESEIIEAAKAANAHDFITS 1105
Query: 461 LPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIK 520
L GY+T G+ G LS G++Q I++ARA+LK+P +++LDEA S++D ++E +VQ+A+ +
Sbjct: 1106 LSNGYDTCCGDRGVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSQSESVVQDALER 1165
Query: 521 LMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR--KGYFYKLYTSQ 574
LM GRTS++IAHRLS + D + V+++G +VE G+ LL++ KG ++ L + Q
Sbjct: 1166 LMVGRTSVVIAHRLSTIQKCDTIAVLENGAVVECGNHSSLLAKGPKGAYFSLVSLQ 1221
>pir||B83507 probable ATP-binding/permease fusion ABC transporter PA1113
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9947031|gb|AAG04502.1|AE004541_7 (AE004541) probable
ATP-binding/permease fusion ABC transporter [Pseudomonas
aeruginosa]
Length = 588
Score = 262 bits (663), Expect = 7e-69
Identities = 158/550 (28%), Positives = 295/550 (52%), Gaps = 9/550 (1%)
Query: 28 VVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTE 87
+V+++ +A L+ +R+ +D + + L +L+ + ++ T ++ +
Sbjct: 31 LVALLFTAAITLSLGQGIRLLVDQGFLTASPELLNRYILLFFVLVLGLAVGTFVRFYLVS 90
Query: 88 VFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
G++ + ++R ++ + +++ + F++T + ++ SR+ DT ++ V+ S L L +
Sbjct: 91 WIGERFVADIRKRVFDHLIELHPGFYETNRSSEIQSRLTADTTLLQTVIGSSLSMALRNA 150
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEES 207
L L G ++ M + + KLT + + ++PL++ L FG ++R RE++ ++A + S V E+
Sbjct: 151 LMLVGGVLLMFVTNAKLTSIVVLALPLVIAPILLFGRRVRSLSRESQDRVADVGSYVGET 210
Query: 208 VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
+ I+T++A+ + + F+ + ++ + L +V +++ G
Sbjct: 211 LGQIKTVQAYNHQAQDRQRFAGTVERAFDTARKRIAQRAWLITVVIVLVLGAVGIMLWVG 270
Query: 268 GYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDY 327
G G++S G + AF+ Y+ + + LQ A A ERI E+L + E
Sbjct: 271 GRDVIAGSISAGELAAFVFYSLIVGMAFGTLSEVIGELQRAAGAAERIAELLRARS-EIR 329
Query: 328 EGISVEKL----KGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTT 380
KL G IE + V F Y RP + D++L + P +A+VG +GAGK+T
Sbjct: 330 PPAQPRKLAARVSGRIELQAVRFAYPT-RPEHWAIDDISLAVEPGETLALVGPSGAGKST 388
Query: 381 IANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEA 440
+ +L++RF+DP +G +L DG ++ LR+ V Q LF G++ ENI P A
Sbjct: 389 LFDLLLRFFDPQQGRLLLDGQPIVELDPADLRRSFALVSQNPALFFGSVEENIRYGRPHA 448
Query: 441 KEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILD 500
+V + H+FI+ LP+GY T GE G LS G+RQ +++ARA+L D +++LD
Sbjct: 449 SAAEVEAAARAAHAHEFILGLPQGYATHLGEGGIGLSGGQRQRLAIARALLVDAPVLLLD 508
Query: 501 EALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGEL 560
EA S++D ++E L+Q A+ LM GRT+++IAHRL+ + AD++ V+D GR+V GS L
Sbjct: 509 EATSALDAESEHLIQQALPGLMSGRTTLVIAHRLATVQSADRIAVIDQGRLVAIGSHARL 568
Query: 561 LSRKGYFYKL 570
++ + +L
Sbjct: 569 IAENPLYARL 578
>sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA >gi|1073873|pir||H64045
probable ABC-type transport protein msbA - Haemophilus
influenzae (strain Rd KW20) >gi|1573008|gb|AAC21738.1|
(U32691) ABC transporter, ATP-binding protein (msbA)
[Haemophilus influenzae Rd]
Length = 587
Score = 262 bits (662), Expect = 9e-69
Identities = 168/576 (29%), Positives = 303/576 (52%), Gaps = 5/576 (0%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG 62
D S+L KR + L + V++V +ALA+ Y+L+ +D + L
Sbjct: 10 DFSTLQTFKRLWPMIKPFKAGLIVSGVALVFNALADSGLIYLLKPLLDDGFGKANHSFLK 69
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
+A + + ++ + + + KV+ +R +L + ++ + FF STG L+
Sbjct: 70 MMAFVVVGMIILRGITNFISNYCLAWVSGKVVMTMRRRLFKHLMFMPVSFFDQNSTGRLL 129
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
SRI D+ ++ L+ + + + M +LT+V P++ ++
Sbjct: 130 SRITYDSQMIASSSSGSLITIVREGAYIISLFAVMFYTSWELTIVLFIIGPIIAVLIRLV 189
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
RR + + + +++S E+ + G + + +FG + E F+ VS + + +++
Sbjct: 190 SKIFRRLSKNLQDSMGELTSATEQMLKGHKVVLSFGGQHVEEVHFNHVSNDMRRKSMKMV 249
Query: 243 IYMGIFWPLMN-IASL-LSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
I P++ IASL L+ ++ +A +A + V F R P+ ++ +
Sbjct: 250 TANSISDPVVQVIASLALATVLYLATTPLIAEDNLSAGSFTVVFSSMLAMMR-PLKSLTA 308
Query: 301 MYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYE-KGRPVLKDVN 359
+ QS +AA + ++ ILD E +D E KGE+EF+NV F Y+ K L +++
Sbjct: 309 VNAQFQSGMAACQTLFAILDLEPEKDDGAYKAEPAKGELEFKNVSFAYQGKDELALNNIS 368
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
+P VA+VG++G+GK+TIANL+ RFYD +GEIL DG++ + +LR+ V
Sbjct: 369 FSVPAGKTVALVGRSGSGKSTIANLVTRFYDIEQGEILLDGVNIQDYRLSNLRENCAVVS 428
Query: 420 QETYLFPGTIMENILMANPEA-KEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
Q+ +LF TI NI A + E++I K +FI KLP+ ++T GE G LS
Sbjct: 429 QQVHLFNDTIANNIAYAAQDKYSREEIIAAAKAAYALEFIEKLPQVFDTVIGENGTSLSG 488
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQ +++ARA+L++ ++ILDEA S++D ++E+ +Q+A+ +L + RT ++IAHRLS
Sbjct: 489 GQRQRLAIARALLRNSPVLILDEATSALDTESERAIQSALEELKKDRTVVVIAHRLSTIE 548
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
AD+++V+D G I E G+ LL + G + +L++ Q
Sbjct: 549 NADEILVIDHGEIRERGNHKTLLEQNGAYKQLHSMQ 584
>pir||T34038 hypothetical protein F43E2.4 - Caenorhabditis elegans
>gi|1947137|gb|AAC71121.1| (AF000264) similar to the
ATP-binding transport protein family (ABC transporters).
[Caenorhabditis elegans]
Length = 761
Score = 262 bits (662), Expect = 9e-69
Identities = 148/487 (30%), Positives = 269/487 (54%), Gaps = 5/487 (1%)
Query: 93 VLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAG 152
V +R L +++ ++ F+ T TGD +SR+ +D ++ + + + + + + L G
Sbjct: 268 VTLRIRLDLFTSLIRQDIAFYDTAKTGDTMSRLTSDCQTISSTVSTNVNVFMRNGVMLIG 327
Query: 153 IIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIE 212
+ M+L+ +L +VT +VPL+ I + + + +Q IA+ + + EE V+ +
Sbjct: 328 ALAFMILMSWRLAMVTFIAVPLVGFITKAYSSFYDKISEKLQQTIAETNQMAEEVVSTMR 387
Query: 213 TIRAFGKEKDVEKEFSKVSTETIKAYLRVAI-YMGIFWPLMNIASLLSVIVVIAYGGYLA 271
T+R+F EK K F + T+ + +I Y+ W ++ V+ YGG+L
Sbjct: 388 TVRSFACEKKELKRFEDRLSSTLSVNRKKSIAYLFYTWN-NEFCDNAILVAVLFYGGHLV 446
Query: 272 YKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGIS 331
G + ++ F+ Y + + + + L A+ A +++++++ + + +G+
Sbjct: 447 MTGKMEKEQLITFLLYQMQLGENLYYLSYVMSGLMEAVGASRKVFDLMNRKPQFELDGMQ 506
Query: 332 VEKLKGEIEFRNVWFEYEK--GRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFY 389
+ G I F +V F Y PVLKD+ L I VA+VG +G GK++I +LI FY
Sbjct: 507 RPFVNGNITFSHVGFTYPSRPNNPVLKDLTLSIKSGETVALVGPSGGGKSSIVSLIEHFY 566
Query: 390 DPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVC 449
+P +G + DG+ K I+ +++ V QE L+ G++ NIL A E+D++
Sbjct: 567 EPDEGSVTLDGVPIKDINHVYYHQKVALVAQEPVLYNGSVRHNILYGCDFATEDDMLNAS 626
Query: 450 KELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPK 509
K +HDF+M+L KGY+T+ GE G +S G++Q I++ARA++++P ++ILDEA S++D +
Sbjct: 627 KMANVHDFVMELEKGYDTNCGEKGVQMSGGQKQRIAIARALVRNPAVLILDEATSALDTE 686
Query: 510 TEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLS-RKGYFY 568
+E LVQ A+ + + RT II+AHRLS A+K+ V+ G +V+ G+ EL++ G +Y
Sbjct: 687 SEALVQQALSRCAQERTVIIVAHRLSTIEKANKIAVIVKGCLVQMGTHTELMTDTDGMYY 746
Query: 569 KLYTSQM 575
L + QM
Sbjct: 747 SLVSRQM 753
>pir||T17482 ABC-type transport protein homolog - Amycolatopsis orientalis
>gi|2894187|emb|CAA11793.1| (AJ223999) PCZA363.2
[Amycolatopsis orientalis] >gi|5051822|emb|CAB45051.1|
(AL078635) putative ABC transporter [Amycolatopsis
orientalis]
Length = 650
Score = 262 bits (662), Expect = 9e-69
Identities = 167/580 (28%), Positives = 305/580 (51%), Gaps = 27/580 (4%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQT 83
+A+ + V +L +A+P +L+ ID+ I + ++A L + V T +
Sbjct: 43 VALFGLVAVLESLIVVATPLLLKELIDNGIEKNDLGLVIWMAALTAVLAVLAAGLTLVSG 102
Query: 84 FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGG 143
+ + G+ + +LR Q + + + + FF TG LV R+ + ++ +GLL
Sbjct: 103 YISGKIGEGITYDLRVQALDHVRRLPIAFFTRTQTGVLVGRLHTEL-IMAQQHFTGLLMA 161
Query: 144 LGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSV 203
S++ +++ + L + +++L +PL ++ + G ++R + +
Sbjct: 162 TTSLVMALVVLIELFYLSWLVAVISLALIPLFLVPWVRVGRVIQRLSGRQMDANTGLGGL 221
Query: 204 VEE--SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVI 261
++E +V G + FG+ + EF ++ K + ++++ + + +M + + L+
Sbjct: 222 LQERFNVQGAMLSKLFGRPNEEMAEFEDRASGIRKIGVSLSVWGRMAFVMMALMASLATA 281
Query: 262 VVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD 321
+V GG L GA +G +VA R GPI + M + Q+ + + R++E+LD
Sbjct: 282 LVYGVGGGLVLAGAFQVGTLVAIATLLGRLFGPITQLSGMQELFQTVVVSFSRVFELLDL 341
Query: 322 ENV--EDYEGISVEK-LKGEIEFRNVWFEY------------------EKGR---PVLKD 357
+ + E + + ++K + +IEF NV F Y E+G VL+D
Sbjct: 342 KPLIQERPDAVKLDKDVAPDIEFENVSFRYPTADEVSLASLEHLKAKRERGEVTPDVLRD 401
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
V+ ++ + A+VG +GAGK+TI +L+ R YDP G + G D + ++ S+R+ +G
Sbjct: 402 VSFHVQAGTLTALVGPSGAGKSTITHLVSRLYDPNSGTVRVGGHDLRDLTFDSIREAVGV 461
Query: 418 VPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLS 477
V Q+ YLF TI EN+L A P A E+++I CK I D I LP G +T G+ G +S
Sbjct: 462 VSQDAYLFHDTIRENLLYARPTATEDELIEACKGAQIWDLIESLPLGLDTVTGDRGYRMS 521
Query: 478 VGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSIT 537
GE+Q +++AR +LK+P IV+LDEA + +D ++E VQ A+ + RTS++IAHRLS
Sbjct: 522 GGEKQRLAIARLLLKEPRIVVLDEATAHLDSESEAAVQRALKTALRSRTSLVIAHRLSTI 581
Query: 538 RFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
R AD+++V+D G + E G+ EL+++ G + +LY +Q +
Sbjct: 582 READQILVIDGGGVRERGTHDELMAKGGLYAELYHTQFAD 621
>sp|P55122|HLYB_PASSP LEUKOTOXIN SECRETION ATP-BINDING PROTEIN >gi|457619|gb|AAA16445.1|
(L12148) pllktB [Pasteurella cf. haemolytica 5943B]
>gi|1581689|prf||2117209C leukotoxin secretion protein
[Pasteurella cf. haemolytica]
Length = 708
Score = 261 bits (660), Expect = 2e-68
Identities = 166/567 (29%), Positives = 292/567 (51%), Gaps = 7/567 (1%)
Query: 13 FIKEALSERRT-LAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLS 71
FI + R+ L ++VSI A L +P +V +D ++ + L I + +
Sbjct: 144 FIPAVIKYRKIFLETLLVSIFLQIFA-LITPLFFQVVMDKVLVHRGFSTLNIITVALAIV 202
Query: 72 LVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNV 131
++ + + L+T+ ++ L ++L +L + +F+ + GD V+R+ + +
Sbjct: 203 IIFEIVLSGLRTYIFAHSTSRIDVELGARLFRHLLALPISYFENRRVGDTVARV-RELDQ 261
Query: 132 VNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYR 191
+ + L L + +L M KLTLV L S+P ++ +++ +RR
Sbjct: 262 IRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYILWSIFISPILRRRLD 321
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
+ + A + + ESV I I+A + + K + + RV + I
Sbjct: 322 DKFARGADNQAFLVESVTAINMIKAMAVSPQMTDTWDKQLASYVSSSFRVTVLATIGQQG 381
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ + +++ + G +L G +SIG ++AF + + P+ + ++ +
Sbjct: 382 VQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFTQVGIS 441
Query: 312 LERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP-VLKDVNLYIPPASKVA 369
+ R+ ++L+ E Y+G +S+ +++G+I F+N+ F Y+ P +L +VNL I +
Sbjct: 442 VTRLGDVLNSPT-EQYQGKLSLPEIQGDIAFKNIRFRYKPDAPTILNNVNLEIKKGEVIG 500
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
IVG++G+GK+T+ L+ RFY P G++L DG D LR++IG V Q+ L +I
Sbjct: 501 IVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSI 560
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI ++ P E VI K G HDFI + +GY T GE G LS G+RQ I++ARA
Sbjct: 561 RENIALSEPGMSMERVIYAAKLAGAHDFISDVREGYNTIVGEQGAGLSGGQRQRIAIARA 620
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++ +P I+I DEA S++D ++E ++ M K+ +GRT I+IAHRLS + AD++IV++ G
Sbjct: 621 LVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHRLSTVKNADRIIVMEKG 680
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELL Y Y Q+Q
Sbjct: 681 EIVEQGKHNELLQNNNGLYS-YLHQLQ 706
>gb|AAF18148.1|AF207838_7 (AF207838) ABC transporter CbaT [Carnobacterium piscicola]
Length = 716
Score = 261 bits (660), Expect = 2e-68
Identities = 159/569 (27%), Positives = 298/569 (51%), Gaps = 7/569 (1%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K + + F+ E+ + ++++ + + S Y + +D++I L
Sbjct: 144 KEKVDGVSSFLPIVWKEKTLVFNIILATLFITFFGIGSSYYFQGILDYFIPNQARSTLNI 203
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
++ ++ V + F +++ + GQ + + + +L ++FF T+ +G+++S
Sbjct: 204 VSFGLIIVYVFRVLFEYSRSYLLVILGQHMSMAVMLRYFNHVLNLPMNFFSTRKSGEIIS 263
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R + D N + D L S L I + + V + + + L L+T+ S+P ++ L F
Sbjct: 264 RFL-DANKIVDALASATLSVFLDIGMVLLVGVTLAIQNGTLFLITVASLPFYLVAILAFV 322
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+A + + A ++S + ES+ GIETI+A+ E+ V + + +K R +
Sbjct: 323 KSYEKANQHQIKAGATLNSSIIESLKGIETIKAYNGEEKVYNRVDQEFIQLMKKAFRTST 382
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
I + L+S +++ G Y G +S+G ++ + F P+ N++++
Sbjct: 383 LDNIQQGVKQGIQLISSGIILWIGSYYVMGGTISLGQLITYNALLVFFTDPLQNIINLQV 442
Query: 304 SLQSALAALERIYEIL----DDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVN 359
+Q+A A +R+ EI + + + + IS + + I F NV F Y LK+++
Sbjct: 443 KMQTAHVANKRLNEIFAIETEHKETDTEKIISKDTFQQGIIFDNVSFSYNINSSTLKNIS 502
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
PP SK+A+VG +G+GK+T+A L++ FY P++G I Y I+ I ++LR+ + YVP
Sbjct: 503 CVFPPRSKIALVGVSGSGKSTLAKLLVNFYPPSEGMICYGKINYLDIGYQNLRENVTYVP 562
Query: 420 QETYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
QE++ F GTI+EN+L + + E ++ +C + DFI K P +ET E LS
Sbjct: 563 QESFFFSGTILENLLFGLDYQPTFEQILDICHVTQLMDFISKQPLRFETILEEGASNLSG 622
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQ +++ARA+LK+ DI+IL EA S +D E + +++L E +T I IAH L+I +
Sbjct: 623 GQRQRLAIARALLKNADILILGEATSGLDTLLEHAILENLLQLKE-KTIIFIAHHLAIAK 681
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYF 567
D+V+V+ +G++VE+G+ EL G +
Sbjct: 682 ACDQVVVLHEGKLVEQGTHDELRYNNGMY 710
>pir||A71943 multi-drug resistance protein - Helicobacter pylori (strain J99)
>gi|4154873|gb|AAD05924.1| (AE001470) multi-drug
resistance protein [Helicobacter pylori J99]
Length = 551
Score = 261 bits (659), Expect = 2e-68
Identities = 160/546 (29%), Positives = 287/546 (52%), Gaps = 4/546 (0%)
Query: 11 KRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLL 70
+R+ K ++ +V+ S + AL+ Y+++ +D I L + L +L
Sbjct: 6 RRYSKYLKEHYKSFIVVLFSSLVVALSTAWGTYLVKPTLDEIFINKDTHMLKILPFLVIL 65
Query: 71 SLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTN 130
+ + + + T++T G +++ +R+ + E +L+ +DFF G+L++RI ND
Sbjct: 66 AYLGKSGGMYVGTYFTNFIGLDIVKKIRNAMLESLLKMEMDFFNRTKKGELIARITNDIG 125
Query: 131 VVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAY 190
++ L + L L L++ G++ ++ KL LV L +PL I K+++
Sbjct: 126 LIRASLSNYLSESLREGLTIVGLVGVVIYQSPKLALVGLVIMPLAAIPISKIIRKVKKLA 185
Query: 191 RETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWP 250
+ ++ AKI++ + E +E I+ EK + F K + K ++ I P
Sbjct: 186 KAHQESNAKITARLSEVFNNVEAIKISNGEKLEHRAFVKENEAFFKIGIKNIAVAEISSP 245
Query: 251 LMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALA 310
LM +++ +VI GG KG +S+G +FI PI + + + Q AL
Sbjct: 246 LMEFLGSIAIALVIYLGGNEVIKGHISVGAFFSFITALFMLYTPIKRLTRIVSNFQEALV 305
Query: 311 ALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEY---EKGRPVLKDVNLYIPPASK 367
A +RI+EIL+ E ++++ IEF+ VW Y ++ R VL D+NL
Sbjct: 306 ASDRIHEILEREPAIIDGELTLDDAIHTIEFKKVWLAYALEDQERYVLSDINLKFQQNEI 365
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
VA+ G++G+GK+++ NLI+R Y+P+KGEI + + I++KSLR++I V Q ++F G
Sbjct: 366 VALKGESGSGKSSLVNLILRLYEPSKGEIFINDQKIESITQKSLREKISVVTQRVFIFNG 425
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
++ EN+ E E + K+ DF+ K+P G E+ E G LS G+RQ I++A
Sbjct: 426 SVAENVAY-GLEIDEIKIKECLKKAQALDFVEKMPHGIESVLDEFGANLSGGQRQRIAIA 484
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
RA+ KD ++I DEA S++D TE+ V+ ++++L + R I+I+H S + A K + ++
Sbjct: 485 RALYKDAQVLIFDEATSALDNHTEESVKQSILELKQNRLIILISHNPSTLKLATKHVKLE 544
Query: 548 DGRIVE 553
GR++E
Sbjct: 545 HGRLIE 550
>gi|4502457 ATP-binding cassette, sub-family B (MDR/TAP), member 11; ABC member
16, MDR/TAP subfamily; bile salt export pump;
progressive familial intrahepatic cholestasis 2 [Homo
sapiens] >gi|3873243|gb|AAC77455.1| (AF091582) bile salt
export pump [Homo sapiens]
Length = 1321
Score = 260 bits (658), Expect = 3e-68
Identities = 164/505 (32%), Positives = 265/505 (52%), Gaps = 12/505 (2%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
+Q + + + ++ +R +I++ + +F S G+L +R +D N +ND + +
Sbjct: 158 IQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQM 217
Query: 141 LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKI 200
+ + S + KLTLV ++ PL+ I A G + + + AK
Sbjct: 218 ALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKA 277
Query: 201 SSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSV 260
V +E ++ + T+ AFG EK + + K + +R I MG F + L
Sbjct: 278 GVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCY 337
Query: 261 IVVIAYGGYLAY-KGAVSIGVVVAFIQYAQRFRGPIN--NVVSMYDSLQSALAALERIYE 317
V YG L +G + G +V + G +N N ++ + AA I+E
Sbjct: 338 AVAFWYGSTLVLDEGEYTPGTLVQI--FLSVIVGALNLGNASPCLEAFATGRAAATSIFE 395
Query: 318 ILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIV 371
+D + + D +G ++++KGEIEF NV F Y RP +L D+N+ I P A+V
Sbjct: 396 TIDRKPIIDCMSEDGYKLDRIKGEIEFHNVTFHYPS-RPEVKILNDLNMVIKPGEMTALV 454
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G +GAGK+T LI RFYDP +G + DG D + ++ + LR +IG V QE LF TI E
Sbjct: 455 GPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAE 514
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI +A ED+++ KE ++FIM LP+ ++T GE G +S G++Q +++ARA++
Sbjct: 515 NIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALI 574
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
++P I++LD A S++D ++E +VQ + K+ G T I +AHRLS R AD +I + G
Sbjct: 575 RNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTA 634
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQ 576
VE G+ ELL RKG ++ L T Q Q
Sbjct: 635 VERGTHEELLERKGVYFTLVTLQSQ 659
Score = 240 bits (606), Expect = 3e-62
Identities = 167/567 (29%), Positives = 283/567 (49%), Gaps = 25/567 (4%)
Query: 27 VVVSIVGSALANLASP---YILRVAIDHYIIPGRYKE---LGFIAMLYLLSLVAQWFFTT 80
++V VG+A+ +P ++ + + IP + ++ + + +L++ F
Sbjct: 755 MLVGSVGAAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQF 814
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGDLVSRIINDTNVVNDVLVS 138
LQ + G+ + + LR +L ++ +F S G L +R+ D + V S
Sbjct: 815 LQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGS 874
Query: 139 GLLGGLGSIL-SLAGIIVAMLL---LDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
+ G I+ S + VAM++ KL+LV L P + + + +
Sbjct: 875 QI----GMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDK 930
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
Q + + + E+++ I T+ GKE+ + + K ++ A G +
Sbjct: 931 QALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQC 990
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
++ YGGYL + V I + S S A + R
Sbjct: 991 IMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAAR 1050
Query: 315 IYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKV 368
+++LD + +V + G + +G+I+F + F Y RP VL +++ I P +
Sbjct: 1051 FFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPS-RPDSQVLNGLSVSISPGQTL 1109
Query: 369 AIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGT 428
A VG +G GK+T L+ RFYDP +G+++ DG D KK++ + LR IG V QE LF +
Sbjct: 1110 AFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACS 1169
Query: 429 IMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISL 486
IM+NI + E E VI K+ +HDF+M LP+ YET+ G G LS GE+Q I++
Sbjct: 1170 IMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAI 1229
Query: 487 ARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVV 546
ARA+++DP I++LDEA S++D ++E+ VQ A+ K EGRT I+IAHRLS + AD + V+
Sbjct: 1230 ARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVM 1289
Query: 547 DDGRIVEEGSPGELLSRKGYFYKLYTS 573
G ++E+G+ EL+++KG +YKL T+
Sbjct: 1290 AQGVVIEKGTHEELMAQKGAYYKLVTT 1316
>pir||T32865 hypothetical protein ZK484.2 - Caenorhabditis elegans
>gi|2746911|gb|AAB95060.1| (AF040659) similar to the
ATP-binding transport protein family [Caenorhabditis
elegans]
Length = 811
Score = 260 bits (657), Expect = 3e-68
Identities = 144/486 (29%), Positives = 269/486 (54%), Gaps = 6/486 (1%)
Query: 95 RNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGII 154
R +R+ L +++ + FF TG++ SR+ D +++ L + ++ L G +
Sbjct: 273 RQIRNDLFRSVVKQEIGFFDMNKTGEICSRLSADCQTMSNTLSLYMNVLTRNLTMLFGSL 332
Query: 155 VAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETI 214
+ M L KL+++TL ++P++ ++ FG ET+ +AK + V EE ++ I T+
Sbjct: 333 IFMFTLSWKLSMITLINIPIIFLVNKIFGVWYDMLSEETQNSVAKANDVAEEVLSSIRTV 392
Query: 215 RAFGKEKDVEKEFSKVSTETIK-AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYK 273
++F E F T+K A +V + +G+ W + + + +V+ YGG+L +
Sbjct: 393 KSFACENYESSRFMTFLNVTLKIATRKVFVVIGLIWS-NELLQMGILTIVLWYGGHLVIE 451
Query: 274 GAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD-DENVEDYEGISV 332
V G++V+F+ Y + + + +++ L A+ A +++E +D VE+ +
Sbjct: 452 NKVESGLLVSFLLYQFQLGENLRELGEVWNGLMQAVGASRKVFEFIDRPPRVENTGTYAP 511
Query: 333 EKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYD 390
+ + G+IEFR+V F Y P+++D+ + P VA+VG +G GK++ ++ FY+
Sbjct: 512 DGMTGKIEFRHVAFSYPIRPDLPIMEDLTFTVEPGEVVALVGPSGGGKSSCIAMLEHFYE 571
Query: 391 PTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCK 450
PT GE+L DG+ ++ K L ++ V QE L+ ++ ENI + ++ V K
Sbjct: 572 PTSGEVLIDGVPVREYDHKFLHTKVALVGQEPVLYARSVTENIGYGLDKYDDDMVQNSAK 631
Query: 451 ELGIHDFIMK-LPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPK 509
H FIM GY T+ GE G +S G++Q I++ARA+++ P +++LDEA S++D +
Sbjct: 632 LANAHTFIMNDTTDGYNTNVGEKGSQMSGGQKQRIAIARALVRQPVVLLLDEATSALDAE 691
Query: 510 TEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYK 569
+E VQ A+ K ++G+T I+IAHRLS ADK++V++ G++ + G+ L+ ++G + +
Sbjct: 692 SEHTVQEAISKNLKGKTVILIAHRLSTVENADKIVVINKGKVEQLGNHKTLMEQEGLYKQ 751
Query: 570 LYTSQM 575
L QM
Sbjct: 752 LVQRQM 757
>dbj|BAB02854.1| (AB026644) multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1240
Score = 260 bits (657), Expect = 3e-68
Identities = 166/523 (31%), Positives = 272/523 (51%), Gaps = 13/523 (2%)
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFK--TKSTGDL 121
+A+LY+ W L+ + G++ +R + +L+ ++ +F ST D+
Sbjct: 82 VALLYVAC--GSWVICFLEGYCWTRTGERQAARMREKYLRAVLRQDVGYFDLHVTSTSDV 139
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALY 181
++ I +D+ V+ D L L L + + + +L +LT+V + L+++ L
Sbjct: 140 ITSISSDSLVIQDFLSEKLPNFLMNASAFVASYIVSFILMWRLTIVGFPFIILLLVPGLM 199
Query: 182 FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRV 241
+G + R+ ++ + S+ E++++ + T+ AFG E + +FS ++K LR
Sbjct: 200 YGRALVSISRKIHEQYNEAGSIAEQAISSVRTVYAFGSENKMIGKFSTALRGSVKLGLRQ 259
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
+ GI + + + YG L G V I + +S
Sbjct: 260 GLAKGITIGSNGVTHAIWAFLTW-YGSRLVMNHGSKGGTVFVVISCITYGGVSLGQSLSN 318
Query: 302 YDSLQSALAALERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VL 355
A A ERI E++ D + EG +E++KGE+EF +V F Y RP +
Sbjct: 319 LKYFSEAFVAWERILEVIKRVPDIDSNKKEGQILERMKGEVEFNHVKFTY-LSRPETTIF 377
Query: 356 KDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI 415
D+ L IP VA+VG +G+GK+T+ +L+ RFYDP GEIL DG+ K+ LR ++
Sbjct: 378 DDLCLKIPAGKTVALVGGSGSGKSTVISLLQRFYDPIAGEILIDGVSIDKLQVNWLRSQM 437
Query: 416 GYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKL 475
G V QE LF +I ENIL +A ++V+ K H FI + P GY+T GE G
Sbjct: 438 GLVSQEPVLFATSITENILFGKEDASLDEVVEAAKASNAHTFISQFPLGYKTQVGERGVQ 497
Query: 476 LSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLS 535
+S G++Q I++ARA++K P I++LDEA S++D ++E++VQ ++ GRT+I+IAHRLS
Sbjct: 498 MSGGQKQRIAIARAIIKSPKILLLDEATSALDSESERVVQESLDNASIGRTTIVIAHRLS 557
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSR-KGYFYKLYTSQMQE 577
R AD + V+ +G+IVE GS ELL R G + L + Q E
Sbjct: 558 TIRNADVICVIHNGQIVETGSHEELLKRIDGQYTSLVSLQQME 600
Score = 243 bits (613), Expect = 5e-63
Identities = 177/527 (33%), Positives = 279/527 (52%), Gaps = 34/527 (6%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVF-GQKVLRNLRSQLHEKILQSNLDFFKT-- 115
KE I +L + L F + Y + G+ + + +R Q+ KIL +++F
Sbjct: 709 KEKTRIYVLLFVGLAIFSFLVNISQHYGFAYMGEYLTKRIREQMLSKILTFEVNWFDIDD 768
Query: 116 KSTGDLVSRIINDTNVVNDVLVSGLLGGLGSIL--SLAGIIVAM---LLLDVKLTLVTLT 170
S+G + SR+ D NVV ++G S+L +++ +I+A L++ +L +V ++
Sbjct: 769 NSSGAICSRLAKDANVVRS-----MVGDRMSLLVQTISAVIIACIIGLVIAWRLAIVMIS 823
Query: 171 SVPLMVIIALYFGGKMRRAYRETRQKIAKISS-VVEESVAGIETIRAFGKEKDVEKEFSK 229
PL +++ Y + ++ E K SS + E+V+ I TI AF ++ + K K
Sbjct: 824 VQPL-IVVCFYTQRVLLKSLSEKASKAQDESSKLAAEAVSNIRTITAFSSQERIIKLLKK 882
Query: 230 VST----ETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGA-VSIGVVVAF 284
V E++ I +G L+ S L+ YGG L G VS F
Sbjct: 883 VQEGPRRESVHRSWLAGIVLGTSRSLITCTSALN----FWYGGRLIADGKIVSKAFFEIF 938
Query: 285 IQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENV---EDYEGISVEKLKGEIEF 341
+ + R I + +M L L A+ ++ +LD ++ +G EK+KG+I F
Sbjct: 939 LIFVTTGR-VIADAGTMTTDLARGLDAVGSVFAVLDRCTTIEPKNPDGYVAEKIKGQITF 997
Query: 342 RNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILY 398
NV F Y RP + ++ ++ I AIVG +G+GK+TI LI RFYDP KG +
Sbjct: 998 LNVDFAYPT-RPDVVIFENFSIEIDEGKSTAIVGTSGSGKSTIIGLIERFYDPLKGTVKI 1056
Query: 399 DGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAK--EEDVIRVCKELGIHD 456
DG D + +SLRK I V QE LF GTI ENI+ K E ++I K HD
Sbjct: 1057 DGRDIRSYHLRSLRKYISLVSQEPMLFAGTIRENIMYGGTSDKIDESEIIEAAKAANAHD 1116
Query: 457 FIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQN 516
FI L GY+T+ G+ G LS G++Q I++ARA+LK+P +++LDEA S++D K+E++VQ+
Sbjct: 1117 FITSLSNGYDTNCGDKGVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSKSERVVQD 1176
Query: 517 AMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR 563
A+ ++M GRTSI+IAHRLS + D ++V+ G+IVE G+ LL +
Sbjct: 1177 ALERVMVGRTSIMIAHRLSTIQNCDMIVVLGKGKIVESGTHSSLLEK 1223
>dbj|BAB02858.1| (AB026644) multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1262
Score = 260 bits (657), Expect = 3e-68
Identities = 165/503 (32%), Positives = 271/503 (53%), Gaps = 23/503 (4%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFK--TKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
G++ +R + +L+ ++ +F ST D+++ + +DT V+ DVL L L S
Sbjct: 126 GERQASRMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDTLVIQDVLSEKLPNFLMSA 185
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEES 207
+ + ++ +LT+V L++I L G + R+ R++ + S+ E++
Sbjct: 186 SAFVASYIVGFIMLWRLTIVGFPFFILLLIPGLMCGRALINISRKIREEYNEAGSIAEQA 245
Query: 208 VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
++ + T+ AFG E+ + +FS ++K LR I GI ++ S V A
Sbjct: 246 ISLVRTVYAFGSERKMISKFSAALEGSVKLGLRQGIAKGI--------AIGSNGVTYAIW 297
Query: 268 GYLAYKGAVSI-------GVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD 320
G++ + G+ + G + A I + +S A+ A ERI E++
Sbjct: 298 GFMTWYGSRMVMYHGAKGGTIFAVIICITYGGTSLGRGLSNLKYFSEAVVAGERIIEVIK 357
Query: 321 ---DENVEDYEGISVEKLKGEIEFRNVWFEYEKG--RPVLKDVNLYIPPASKVAIVGKTG 375
D + ++ G +E +KGE++F++V F Y P+ D+ L IP VA+VG +G
Sbjct: 358 RVPDIDSDNPRGQVLENIKGEVQFKHVKFMYSSRPETPIFDDLCLRIPSGKSVALVGGSG 417
Query: 376 AGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILM 435
+GK+T+ +L+ RFYDP GEIL DG+ KK+ K LR ++G V QE LF +I ENIL
Sbjct: 418 SGKSTVISLLQRFYDPIVGEILIDGVSIKKLQVKWLRSQMGLVSQEPALFATSIEENILF 477
Query: 436 ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPD 495
+A ++V+ K HDFI + P GY+T GE G +S G++Q IS+ARA++K P
Sbjct: 478 GKEDASFDEVVEAAKSSNAHDFISQFPLGYKTQVGERGVQMSGGQKQRISIARAIIKSPT 537
Query: 496 IVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEG 555
+++LDEA S++D ++E++VQ A+ GRT+I+IAHRLS R D + V +G+IVE G
Sbjct: 538 LLLLDEATSALDSESERVVQEALDNATIGRTTIVIAHRLSTIRNVDVICVFKNGQIVETG 597
Query: 556 SPGELLSR-KGYFYKLYTSQMQE 577
S EL+ G + L Q+ E
Sbjct: 598 SHEELMENVDGQYTSLVRLQIME 620
Score = 234 bits (591), Expect = 2e-60
Identities = 169/532 (31%), Positives = 277/532 (51%), Gaps = 33/532 (6%)
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KST 118
+G + +L+S++ Q+ F + G+ + + +R + K+L + +F S+
Sbjct: 742 VGLAVLCFLISIIQQYSFAYM--------GEYLTKRIRENILSKLLTFEVSWFDEDENSS 793
Query: 119 GDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAM-LLLDVKLTLVTLTSVPLMVI 177
G + SR+ D NVV LV + L +S + + L + KL++V + P V+
Sbjct: 794 GSICSRLAKDANVVRS-LVGERVSLLVQTISAVSVACTLGLAISWKLSIVMIAIQP--VV 850
Query: 178 IALYFGGKMRRAYRETRQKIAKI----SSVVEESVAGIETIRAFGKEKDVEKEFSKVSTE 233
+ ++ R + +K K S + E+V+ I TI AF ++ + K V
Sbjct: 851 VGCFY--TQRIVLKSISKKAIKAQDESSKLAAEAVSNIRTITAFSSQERILKLLKMVQEG 908
Query: 234 TIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAV-SIGVVVAFIQYAQRFR 292
+ +R + GI + + YG L G + S FI + R
Sbjct: 909 PQRENIRQSWLAGIVLATSRSLMTCTSALNYWYGARLIIDGKITSKAFFELFILFVSTGR 968
Query: 293 GPINNVVSMYDSLQSALAALERIYEILDD-ENVEDY--EGISVEKLKGEIEFRNVWFEYE 349
I + +M L A+ ++ +LD N+E +G + +KG+I+F NV F Y
Sbjct: 969 -VIADAGAMTMDLAKGSDAVGSVFAVLDRYTNIEPEKPDGFVPQNIKGQIKFVNVDFAYP 1027
Query: 350 KGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKI 406
RP + K+ ++ I AIVG +G+GK+TI LI RFYDP KG + DG D +
Sbjct: 1028 T-RPDVIIFKNFSIDIDEGKSTAIVGPSGSGKSTIIGLIERFYDPLKGIVKIDGRDIRSY 1086
Query: 407 SRKSLRKRIGYVPQETYLFPGTIMENILM--ANPEAKEEDVIRVCKELGIHDFIMKLPKG 464
+SLR+ IG V QE LF GTI ENI+ A+ + E ++I K HDFI+ L G
Sbjct: 1087 HLRSLRQHIGLVSQEPILFAGTIRENIMYGGASDKIDESEIIEAAKAANAHDFIVTLSDG 1146
Query: 465 YETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEG 524
Y+T G+ G LS G++Q I++ARA+LK+P +++LDEA S++D ++E++VQ+A+ +LM G
Sbjct: 1147 YDTYCGDRGVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDNQSERMVQDALGRLMVG 1206
Query: 525 RTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR--KGYFYKLYTSQ 574
RTS++IAHRLS + D + V+D G++VE G+ LL++ G ++ L + Q
Sbjct: 1207 RTSVVIAHRLSTIQNCDTITVLDKGKVVECGTHSSLLAKGPTGVYFSLVSLQ 1258
>pir||I39646 secretion protein B - Actinobacillus pleuropneumoniae
>gi|505571|emb|CAA48587.1| (X68595) secretion protein B
[Actinobacillus pleuropneumoniae]
Length = 707
Score = 259 bits (655), Expect = 6e-68
Identities = 167/566 (29%), Positives = 288/566 (50%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ + + L +P +V +D ++ + L I + + +
Sbjct: 143 FIPAVIKYRKIFIETLIVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNVITVALAIVV 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + L+T+ ++ L ++L +L + +F+ + GD V+R+ +
Sbjct: 203 LFEIVLNGLRTYIFAHSTSRIDVELGARLFRHLLALPISYFENRRVGDTVARVRELDQIR 262
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L + S V M KLTLV L S+P + +++ +RR E
Sbjct: 263 NFLTGQALTSVLDLMFSFIFFAV-MWYYSPKLTLVILGSLPFYMGWSIFISPILRRRLDE 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + A RV I +
Sbjct: 322 KFARGADNQSFLVESVTAINTIKALAVTPQMTNTWDKQLASYVSAGFRVTTLATIGQQGV 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +++ + G +L G +SIG ++AF + + P+ + ++ Q ++
Sbjct: 382 QFIQKVVMVITLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E Y+G +++ ++KG+I FRN+ F Y+ PV L DVNL I + I
Sbjct: 442 TRLGDVLNSPT-ESYQGKLALPEIKGDITFRNIRFRYKPDAPVILNDVNLSIQQGEVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ LI RFY P G++L DG D LR+++G V Q+ L +I
Sbjct: 501 VGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIR 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +A+P E ++ K G H+FI +L +GY T GE G LS Q I++ARA+
Sbjct: 561 DNIALADPGMPMEKIVHAAKLAGAHEFISELREGYNTIVGEQGAGLSGRATQRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M ++ +GRT IIIAHRLS + AD++IV++ G+
Sbjct: 621 VNNPKILIFDEATSALDYESEHIIMRNMHQICKGRTVIIIAHRLSTVKNADRIIVMEKGQ 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELL+ Y Y Q+Q
Sbjct: 681 IVEQGKHKELLADPNGLYH-YLHQLQ 705
>gb|AAG26946.1|AC069471_7 (AC069471) P-glycoprotein, putative [Arabidopsis thaliana]
Length = 1247
Score = 259 bits (655), Expect = 6e-68
Identities = 164/536 (30%), Positives = 279/536 (51%), Gaps = 25/536 (4%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--K 116
+E+ +A++++ + + LQ ++ + G+++ +R L IL + + +F
Sbjct: 721 REVDKVAIIFVGAGIVTAPIYILQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDEN 780
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+TG L S + D +V + L + ++ + ++ V PL++
Sbjct: 781 NTGSLTSILAADATLVRSAIADRLSTIVQNLSLTITALALAFFYSWRVAAVVTACFPLLI 840
Query: 177 IIALY-------FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFS- 228
+L FGG RAY ++ +S+ E+++ I T+ AF EK + ++F+
Sbjct: 841 AASLTEQLFLKGFGGDYTRAY-------SRATSLAREAISNIRTVAAFSAEKQISEQFTC 893
Query: 229 KVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYA 288
++S T A LR I G + L + S + + Y L + + +
Sbjct: 894 ELSKPTKSALLRGHI-SGFGYGLSQCLAFCSYALGLWYISVLIKRNETNFEDSIKSFMVL 952
Query: 289 QRFRGPINNVVSMYDSLQSALAALERIYEILDDENV---EDYEGISVEKLKGEIEFRNVW 345
+ +++ + AL ++ +L E + V +KG+IEFRNV
Sbjct: 953 LVTAYSVAETLALTPDIVKGTQALGSVFRVLHRETEIPPDQPNSRLVTHIKGDIEFRNVS 1012
Query: 346 FEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGID 402
F Y RP + K++NL + +A+VG +G+GK+T+ LIMRFYDP+ G + DG D
Sbjct: 1013 FAYPT-RPEIAIFKNLNLRVSAGKSLAVVGPSGSGKSTVIGLIMRFYDPSNGNLCIDGHD 1071
Query: 403 GKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLP 462
K ++ +SLRK++ V QE LF +I ENI N A E ++I K H+FI ++
Sbjct: 1072 IKSVNLRSLRKKLALVQQEPALFSTSIHENIKYGNENASEAEIIEAAKAANAHEFISRME 1131
Query: 463 KGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLM 522
+GY T G+ G LS G++Q +++ARA+LKDP +++LDEA S++D E+ VQ A+ KLM
Sbjct: 1132 EGYMTHVGDKGVQLSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSAEKQVQEALDKLM 1191
Query: 523 EGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
+GRT+I++AHRLS R AD ++V+ G++VE+GS EL+S+ FYK TS + V
Sbjct: 1192 KGRTTILVAHRLSTIRKADTIVVLHKGKVVEKGSHRELVSKSDGFYKKLTSLQEAV 1247
Score = 240 bits (606), Expect = 3e-62
Identities = 165/525 (31%), Positives = 267/525 (50%), Gaps = 18/525 (3%)
Query: 63 FIAMLYLLSLVAQWFFTT--LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKST-G 119
++ L L++LV+ W +QT G++ LR + IL ++ FF T++
Sbjct: 96 YLVYLGLVNLVSAWIGVACWMQT------GERQTARLRINYLKSILAKDITFFDTEARDS 149
Query: 120 DLVSRIINDTNVVNDVLVSGLLGGLGSILS-LAGIIVAMLLLDVKLTLVTLTSVPLMVII 178
+ + I +D +V D + L + +AG ++ L + +LTL+TL VPL+ I
Sbjct: 150 NFIFHISSDAILVQDAIGDKTGHVLRYLCQFIAGFVIGFLSV-WQLTLLTLGVVPLIAIA 208
Query: 179 ALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAY 238
+ M ++ A V EE ++ + T+ AF E+ K +S + +K
Sbjct: 209 GGGYAIVMSTISEKSEAAYADAGKVAEEVMSQVRTVYAFVGEEKAVKSYSNSLKKALKLS 268
Query: 239 LRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNV 298
R + G+ L + ++ Y L G + I +
Sbjct: 269 KRSGLAKGLGVGLTYSLLFCAWALLFWYASLLVRHGKTNGAKAFTTILNVIYSGFALGQA 328
Query: 299 VSMYDSLQSALAALERIYEILDDENVEDYE----GISVEKLKGEIEFRNVWFEYEKGRP- 353
V ++ A I++++ + N+E E G +++ + G+IEF V F Y RP
Sbjct: 329 VPSLSAISKGRVAAANIFKMIGNNNLESSERLENGTTLQNVVGKIEFCGVSFAYPS-RPN 387
Query: 354 -VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
V ++++ I A VG +G+GK+TI +++ RFY+P GEIL DG D K + K LR
Sbjct: 388 MVFENLSFTIHSGKTFAFVGPSGSGKSTIISMVQRFYEPRSGEILLDGNDIKNLKLKWLR 447
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEA 472
+++G V QE LF TI NIL+ +A + +I K FI LP GY T GE
Sbjct: 448 EQMGLVSQEPALFATTIASNILLGKEKANMDQIIEAAKAANADSFIKSLPNGYNTQVGEG 507
Query: 473 GKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAH 532
G LS G++Q I++ARA+L++P I++LDEA S++D ++E++VQ A+ +ME RT+I+IAH
Sbjct: 508 GTQLSGGQKQRIAIARAVLRNPKILLLDEATSALDAESEKIVQQALDNVMEKRTTIVIAH 567
Query: 533 RLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
RLS R DK++V+ DG++ E GS EL+SR G + L Q E
Sbjct: 568 RLSTIRNVDKIVVLRDGQVRETGSHSELISRGGDYATLVNCQDTE 612
>gi|11430459 ATP-binding cassette, sub-family B (MDR/TAP), member 11 [Homo
sapiens]
Length = 1321
Score = 259 bits (655), Expect = 6e-68
Identities = 163/505 (32%), Positives = 265/505 (52%), Gaps = 12/505 (2%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
+Q + + + ++ +R +I++ + +F S G+L +R +D N +ND + +
Sbjct: 158 IQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQM 217
Query: 141 LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKI 200
+ + S + KLTLV ++ PL+ I A G + + + AK
Sbjct: 218 ALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKA 277
Query: 201 SSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSV 260
V +E ++ + T+ AFG EK + + K + +R I MG F + L
Sbjct: 278 GVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCY 337
Query: 261 IVVIAYGGYLAY-KGAVSIGVVVAFIQYAQRFRGPIN--NVVSMYDSLQSALAALERIYE 317
+ YG L +G + G +V + G +N N ++ + AA I+E
Sbjct: 338 ALAFWYGSTLVLDEGEYTPGTLVQI--FLSVIVGALNLGNASPCLEAFATGRAAATSIFE 395
Query: 318 ILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIV 371
+D + + D +G ++++KGEIEF NV F Y RP +L D+N+ I P A+V
Sbjct: 396 TIDRKPIIDCMSEDGYKLDRIKGEIEFHNVTFHYPS-RPEVKILNDLNMVIKPGEMTALV 454
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G +GAGK+T LI RFYDP +G + DG D + ++ + LR +IG V QE LF TI E
Sbjct: 455 GPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAE 514
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI +A ED+++ KE ++FIM LP+ ++T GE G +S G++Q +++ARA++
Sbjct: 515 NIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALI 574
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
++P I++LD A S++D ++E +VQ + K+ G T I +AHRLS R AD +I + G
Sbjct: 575 RNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTA 634
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQ 576
VE G+ ELL RKG ++ L T Q Q
Sbjct: 635 VERGTHEELLERKGVYFTLVTLQSQ 659
Score = 240 bits (606), Expect = 3e-62
Identities = 167/567 (29%), Positives = 283/567 (49%), Gaps = 25/567 (4%)
Query: 27 VVVSIVGSALANLASP---YILRVAIDHYIIPGRYKE---LGFIAMLYLLSLVAQWFFTT 80
++V VG+A+ +P ++ + + IP + ++ + + +L++ F
Sbjct: 755 MLVGSVGAAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQF 814
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGDLVSRIINDTNVVNDVLVS 138
LQ + G+ + + LR +L ++ +F S G L +R+ D + V S
Sbjct: 815 LQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGS 874
Query: 139 GLLGGLGSIL-SLAGIIVAMLL---LDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
+ G I+ S + VAM++ KL+LV L P + + + +
Sbjct: 875 QI----GMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDK 930
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
Q + + + E+++ I T+ GKE+ + + K ++ A G +
Sbjct: 931 QALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQC 990
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
++ YGGYL + V I + S S A + R
Sbjct: 991 IMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAAR 1050
Query: 315 IYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKV 368
+++LD + +V + G + +G+I+F + F Y RP VL +++ I P +
Sbjct: 1051 FFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPS-RPDSQVLNGLSVSISPGQTL 1109
Query: 369 AIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGT 428
A VG +G GK+T L+ RFYDP +G+++ DG D KK++ + LR IG V QE LF +
Sbjct: 1110 AFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACS 1169
Query: 429 IMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISL 486
IM+NI + E E VI K+ +HDF+M LP+ YET+ G G LS GE+Q I++
Sbjct: 1170 IMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAI 1229
Query: 487 ARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVV 546
ARA+++DP I++LDEA S++D ++E+ VQ A+ K EGRT I+IAHRLS + AD + V+
Sbjct: 1230 ARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVM 1289
Query: 547 DDGRIVEEGSPGELLSRKGYFYKLYTS 573
G ++E+G+ EL+++KG +YKL T+
Sbjct: 1290 AQGVVIEKGTHEELMAQKGAYYKLVTT 1316
>pir||T31073 multidrug resistance p-glycoprotein - nematode (Haemonchus
contortus) >gi|3057042|gb|AAC38987.1| (AF003908)
P-glycoprotein [Haemonchus contortus]
Length = 1275
Score = 259 bits (654), Expect = 8e-68
Identities = 163/525 (31%), Positives = 273/525 (51%), Gaps = 25/525 (4%)
Query: 67 LYLLSLVAQWFFTT-LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRI 125
LY L L F T+ +Q E F +++ LR + IL+ + +F + TG+L +R+
Sbjct: 116 LYYLGLGFAMFATSYIQIVCWETFAERITHKLRKIYLKAILRQQISWFDIQQTGNLTARL 175
Query: 126 INDTNVVNDVLVSGLLGGLGSILSL---------AGIIVAMLLLDVKLTLVTLTSVPLMV 176
+D V + GLG LSL AG V +TLV + P +V
Sbjct: 176 TDDLERVRE--------GLGDKLSLFIQMVSAFVAGFCVG-FAYSWSMTLVMMVVAPFIV 226
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
I A + + + ++ A ++ EE+ + I T+ + K F + +
Sbjct: 227 ISANWMSKIVATRTQVEQETYAVAGAIAEETFSSIRTVHSICGHKRELTRFEAALEKGRQ 286
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKG-AVSIGVVVAFIQYAQRFRGPI 295
L YMG+ + + +S + YG L A+ G + +
Sbjct: 287 TGLVKYFYMGVGVGFGQMCTYVSYALAFWYGSVLIINDPALDRGRIFTVFFAVMSGSAAL 346
Query: 296 NNVVSMYDSLQSALAALERIYEILDDE-NVEDY--EGISVEKLKGEIEFRNVWFEYEKGR 352
+ +++ A A+ + +++ ++ Y +GI + ++G I F+NV F Y R
Sbjct: 347 GTCLPHLNTISIARGAVRSVLSVINSRPKIDPYSLDGIVLNNMRGSIRFKNVHFSYPSRR 406
Query: 353 --PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
+LK V+L + K+A+VG +G GK+T NL++RFYDPT+G++ D ID ++ +
Sbjct: 407 TLQILKGVSLQVSAGQKIALVGSSGCGKSTNVNLLLRFYDPTRGKVTIDDIDVCDLNVQK 466
Query: 411 LRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAG 470
LR++IG V QE LF GT+ ENI M +A E+V C+ DF +LP+GY T G
Sbjct: 467 LREQIGVVSQEPVLFDGTLFENIKMGYEQATMEEVQEACRVANAADFTKRLPEGYGTRVG 526
Query: 471 EAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
E G LS G++Q I++ARA++K+P I++LDEA S++D + E +VQ A+ K +GRT++I+
Sbjct: 527 ERGVQLSGGQKQRIAIARAIIKNPRILLLDEATSALDTEAESIVQEALEKAQKGRTTVIV 586
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
AHRLS R D++ V +G IVE+G+ EL++++G F+++ +Q+
Sbjct: 587 AHRLSTIRNVDQIFVFKNGTIVEQGTHAELMNKRGVFFEMTQAQV 631
Score = 231 bits (584), Expect = 1e-59
Identities = 158/506 (31%), Positives = 278/506 (54%), Gaps = 35/506 (6%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKT--KSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
G+ + + LR + + +L+ N+ F+ TG L +R D V V L G L S+
Sbjct: 778 GEALTKKLRFEAFKNLLRQNVGFYDDIRHGTGKLCTRFATDAPNVRYVFTR-LPGVLSSV 836
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMV-----IIALYFGGKMRRAYRETRQKIAKISS 202
+++ G +V + +L L+ + VPL++ + + FG KMR E ++ K++S
Sbjct: 837 VTIIGALVIGFIFGWQLALILMVMVPLIIGSGYFEMRMQFGKKMRDT--ELLEEAGKVAS 894
Query: 203 VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA-IYMGIFWPLMNIASLLSVI 261
++V I T+ A +++ + + E + L A Y G+F SLL +
Sbjct: 895 ---QAVENIRTVHALNRQEQFHFMYCEYLKEPYRENLCQAHTYGGVF---AFSQSLLFFM 948
Query: 262 VVIAYGGYLAYKGAVSIG------VVVAFIQYAQRFRGPINNVVSMY--DSLQSALAALE 313
+A+ + GA+ + + V + +A F G + +S + D +++ LAA
Sbjct: 949 YAVAF-----WIGAIFVDNHSMQPIDVYRVFFAFMFCGQMVGNISSFIPDVVKARLAASL 1003
Query: 314 RIYEILDDENVEDYEGISV-EKLKGEIEFRNVWFEYEKGRP--VLKDVNLYIPPASKVAI 370
Y I +++ V +K+ G I FRNV+F Y R VL+ +NL I P + VA+
Sbjct: 1004 LFYLIEHPSEIDNLSEDGVTKKISGHISFRNVYFNYPTRRQIRVLRGLNLEINPGTTVAL 1063
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G GK+T+ L+ RFY+ KG I DG + + ++ ++LR+++ V QE LF TIM
Sbjct: 1064 VGQSGCGKSTVMALLERFYNQNKGVITVDGENIRNMNIRNLREQVCIVSQEPTLFDCTIM 1123
Query: 431 ENIL--MANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLAR 488
ENI + +P+ E V+ K IH+F++ LP+GY+T GE G LS G++Q I++AR
Sbjct: 1124 ENICYGLDDPKPSYEQVVAAAKMANIHNFVLGLPEGYDTRVGEKGTQLSGGQKQRIAIAR 1183
Query: 489 AMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDD 548
A+++DP I++LDEA S++D ++E++VQ+A+ +GRT ++IAHRLS + +D ++++ +
Sbjct: 1184 ALIRDPPILLLDEATSALDTESEKIVQDALEVARQGRTCLVIAHRLSTIQDSDVIVMIQE 1243
Query: 549 GRIVEEGSPGELLSRKGYFYKLYTSQ 574
G+ + G+ LL + + +L +Q
Sbjct: 1244 GKATDRGTHEHLLMKNDLYKRLCETQ 1269
>gb|AAD22645.1|AC007138_9 (AC007138) putative P-glycoprotein-like protein [Arabidopsis
thaliana] >gi|7268567|emb|CAB80676.1| (AL161493)
putative P-glycoprotein-like protein [Arabidopsis
thaliana]
Length = 1230
Score = 259 bits (654), Expect = 8e-68
Identities = 174/529 (32%), Positives = 282/529 (52%), Gaps = 23/529 (4%)
Query: 58 YKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTK- 116
Y LG + +L VA W T G++ +RS + IL+ ++ FF +
Sbjct: 80 YLGLGALGAAFLQ--VACWMIT----------GERQAARIRSLYLKTILRQDIGFFDVEM 127
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+TG++V R+ DT ++ D + + + I + G V L LTLV LTS+PL+
Sbjct: 128 TTGEVVGRMSGDTVLILDAMGEKVGKFIQLISTFVGGFVIAFLRGWLLTLVMLTSIPLLA 187
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
+ + RA + + AK S+VVE+++ I T+ +F EK + ++ K
Sbjct: 188 MSGAAIAIIVTRASSQEQAAYAKASNVVEQTLGSIRTVASFTGEKQAMSSYKELINLAYK 247
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
+ ++ G+ +M + + + +GG + + + G V+ + +
Sbjct: 248 SNVKQGFVTGLGLGVMFLVFFSTYALGTWFGGEMILRKGYTGGAVINVMVTVVSSSIALG 307
Query: 297 NVVSMYDSLQSALAALERIYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP 353
+ + AA +++E ++ E + D G +E ++GEIE R+V F Y RP
Sbjct: 308 QASPCLTAFTAGKAAAYKMFETIEREPLIDTFDLNGKVLEDIRGEIELRDVCFSYP-ARP 366
Query: 354 ---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
V +L IP + A+VG++G+GK+T+ +LI RFYDP G++L DG+D K+ K
Sbjct: 367 KEEVFGGFSLLIPSGTTTALVGESGSGKSTVISLIERFYDPNSGQVLIDGVDLKEFQLKW 426
Query: 411 LRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAG 470
+R +IG V QE LF +IMENI A E++ K FI KLP G ET G
Sbjct: 427 IRGKIGLVSQEPVLFSSSIMENIGYGKEGATVEEIQAASKLANAAKFIDKLPLGLETLVG 486
Query: 471 EAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
E G LS G++Q I++ARA+LKDP I++LDEA S++D ++E++VQ A+ ++M RT++I+
Sbjct: 487 EHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRIMVNRTTVIV 546
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELL-SRKGYFYKLYTSQMQEV 578
AHRLS R AD + V+ G+IVEEGS ELL +G + +L ++QE+
Sbjct: 547 AHRLSTVRNADIIAVIHRGKIVEEGSHSELLKDHEGAYSQLL--RLQEI 593
Score = 228 bits (576), Expect = 1e-58
Identities = 153/517 (29%), Positives = 270/517 (51%), Gaps = 13/517 (2%)
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGD 120
F +M+++L VA + + G +++R +RS EK++ + +F S+G
Sbjct: 704 FWSMIFVLLGVAAVIVYPTTNYLFAIAGGRLIRRIRSMCFEKVVHMEVGWFDEPGNSSGA 763
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
+ +R+ D ++ ++ L + ++ SL ++ ++ ++ L +P + I
Sbjct: 764 MGARLSADAALIRTLVGDSLCLSVKNVASLVTGLIIAFTASWEVAIIILVIIPFIGINGY 823
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
M+ + + K + S V ++V I T+ +F E+ V + + K +TIK+ ++
Sbjct: 824 IQIKFMKGFSADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIK 883
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAY-GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
+ G+ + + + L SV Y G L G + V I+
Sbjct: 884 QGLISGVGFGI-SFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTLTAVGISQAS 942
Query: 300 SMYDSLQSALAALERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP--- 353
S A I+ I+D + D G+ +E +KG+IE ++ F Y+ RP
Sbjct: 943 SFAPDSSKGKGAAVSIFRIIDRISKIDSRDESGMVLENVKGDIELCHISFTYQT-RPDVQ 1001
Query: 354 VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRK 413
V +D+ L I VA+VG++G+GK+T+ +L+ RFYDP G I DG++ KK+ K LR+
Sbjct: 1002 VFRDLCLSIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLRLKWLRQ 1061
Query: 414 RIGYVPQETYLFPGTIMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
++G V QE LF TI NI EA E ++I + H FI + KGY+T GE
Sbjct: 1062 QMGLVGQEPVLFNDTIRANIAYGKGGEEATEAEIIAASELANAHRFISSIQKGYDTVVGE 1121
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G LS G++Q +++ARA++K+P I++LDEA S++D ++E++VQ+A+ ++M RT+I++A
Sbjct: 1122 RGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTIVVA 1181
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFY 568
HRLS + AD + VV +G I E+G+ L++ +G Y
Sbjct: 1182 HRLSTIKNADVIAVVKNGVIAEKGTHETLINIEGGVY 1218
>gb|AAD28285.1|AF136523_1 (AF136523) bile salt export pump [Homo sapiens]
Length = 1321
Score = 259 bits (654), Expect = 8e-68
Identities = 163/505 (32%), Positives = 265/505 (52%), Gaps = 12/505 (2%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
+Q + + + ++ +R +I++ + +F S G+L +R +D N +ND + +
Sbjct: 158 IQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQM 217
Query: 141 LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKI 200
+ + S + KLTLV ++ PL+ I A G + + + AK
Sbjct: 218 ALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKA 277
Query: 201 SSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSV 260
V +E ++ + T+ AFG EK + + K + +R I MG F + L
Sbjct: 278 GVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCY 337
Query: 261 IVVIAYGGYLAY-KGAVSIGVVVAFIQYAQRFRGPIN--NVVSMYDSLQSALAALERIYE 317
+ YG L +G + G +V + G +N N ++ + AA I+E
Sbjct: 338 ALAFWYGSTLVLDEGEYTPGTLVQI--FLSVIVGALNLGNASPCLEAFATGRAAATSIFE 395
Query: 318 ILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIV 371
+D + + D +G ++++KGEIEF NV F Y RP +L D+N+ I P A+V
Sbjct: 396 TIDRKPIIDCMSEDGYKLDRIKGEIEFHNVTFHYPS-RPEVKILNDLNMAIKPGEMTALV 454
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G +GAGK+T LI RFYDP +G + DG D + ++ + LR +IG V QE LF TI E
Sbjct: 455 GPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAE 514
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI +A ED+++ KE ++FIM LP+ ++T GE G +S G++Q +++ARA++
Sbjct: 515 NIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALI 574
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
++P I++LD A S++D ++E +VQ + K+ G T I +AHRLS R AD +I + G
Sbjct: 575 RNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTA 634
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQ 576
VE G+ ELL RKG ++ L T Q Q
Sbjct: 635 VERGTHEELLERKGVYFTLVTLQSQ 659
Score = 240 bits (606), Expect = 3e-62
Identities = 167/567 (29%), Positives = 283/567 (49%), Gaps = 25/567 (4%)
Query: 27 VVVSIVGSALANLASP---YILRVAIDHYIIPGRYKE---LGFIAMLYLLSLVAQWFFTT 80
++V VG+A+ +P ++ + + IP + ++ + + +L++ F
Sbjct: 755 MLVGSVGAAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQF 814
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGDLVSRIINDTNVVNDVLVS 138
LQ + G+ + + LR +L ++ +F S G L +R+ D + V S
Sbjct: 815 LQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGS 874
Query: 139 GLLGGLGSIL-SLAGIIVAMLL---LDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
+ G I+ S + VAM++ KL+LV L P + + + +
Sbjct: 875 QI----GMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDK 930
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
Q + + + E+++ I T+ GKE+ + + K ++ A G +
Sbjct: 931 QALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQC 990
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
++ YGGYL + V I + S S A + R
Sbjct: 991 IMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAAR 1050
Query: 315 IYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKV 368
+++LD + +V + G + +G+I+F + F Y RP VL +++ I P +
Sbjct: 1051 FFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPS-RPDSQVLNGLSVSISPGQTL 1109
Query: 369 AIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGT 428
A VG +G GK+T L+ RFYDP +G+++ DG D KK++ + LR IG V QE LF +
Sbjct: 1110 AFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACS 1169
Query: 429 IMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISL 486
IM+NI + E E VI K+ +HDF+M LP+ YET+ G G LS GE+Q I++
Sbjct: 1170 IMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAI 1229
Query: 487 ARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVV 546
ARA+++DP I++LDEA S++D ++E+ VQ A+ K EGRT I+IAHRLS + AD + V+
Sbjct: 1230 ARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVM 1289
Query: 547 DDGRIVEEGSPGELLSRKGYFYKLYTS 573
G ++E+G+ EL+++KG +YKL T+
Sbjct: 1290 AQGVVIEKGTHEELMAQKGAYYKLVTT 1316
>pir||B64655 multidrug resistance protein - Helicobacter pylori (strain 26695)
>gi|2314232|gb|AAD08127.1| (AE000615) multidrug
resistance protein (msbA) [Helicobacter pylori 26695]
Length = 551
Score = 258 bits (653), Expect = 1e-67
Identities = 159/546 (29%), Positives = 284/546 (51%), Gaps = 4/546 (0%)
Query: 11 KRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLL 70
KR+ K ++ +V+ S + AL+ Y+++ +D I L + L +L
Sbjct: 6 KRYSKYLKEHYKSFIVVLFSSLVVALSTAWGTYLVKPTLDEIFINKDTHMLKILPFLVIL 65
Query: 71 SLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTN 130
+ + + L T++T G +++ +R+ + E +L+ +DFF G+L++RI ND
Sbjct: 66 AYLGKSGGMYLGTYFTNFIGLDIVKKIRNTMLESLLKMEMDFFNRTKKGELIARITNDIG 125
Query: 131 VVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAY 190
++ L + L + L++ G++ ++ KL LV L +PL I K+++
Sbjct: 126 LIRASLSNYLSESIREGLTIVGLVGVVIYQSPKLALVGLVIMPLAAIPISKIIRKVKKLA 185
Query: 191 RETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWP 250
+ ++ AKI++ + E +E I+ EK K F K + K ++ I P
Sbjct: 186 KSHQESNAKITARLSEVFNNVEAIKISNGEKLEHKAFVKENEAFFKIGIKNIAVAEISSP 245
Query: 251 LMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALA 310
LM +++ +VI GG +G +S+G +FI PI + + + Q AL
Sbjct: 246 LMEFLGSIAIALVIYLGGNEVIRGHISVGAFFSFITALFMLYTPIKRLTRIVSNFQEALV 305
Query: 311 ALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEY---EKGRPVLKDVNLYIPPASK 367
A +RI+EIL+ E +++ IEF+ VW Y + R VL D++L
Sbjct: 306 ASDRIHEILEREPAIVDGELTLNNAIHTIEFKKVWLAYTLDNQERYVLNDISLKFQQNEI 365
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
+A+ G++G+GK+++ NLI+R Y+P+KGEI + + I++KSLR++I V Q ++F G
Sbjct: 366 IALKGESGSGKSSLVNLILRLYEPSKGEIFINDQKIESITQKSLREKISVVTQRVFIFNG 425
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
++ EN+ E E + K+ DF+ K+P G E+ E G LS G+RQ I++A
Sbjct: 426 SVAENVAY-GLEIDEVKIKECLKKAQALDFVEKMPHGIESVLDEFGANLSGGQRQRIAIA 484
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
RA+ KD ++I DEA S++D TE+ V+ ++++L + R I+I+H S + A K + ++
Sbjct: 485 RALYKDVQVLIFDEATSALDNNTEESVKQSILELKQNRLIILISHNPSTLKLATKHVKLE 544
Query: 548 DGRIVE 553
GR+ E
Sbjct: 545 HGRLTE 550
>gb|AAG01549.1|AF291822_1 (AF291822) multidrug resistance protein MDR [Trichophyton rubrum]
Length = 1217
Score = 257 bits (651), Expect = 2e-67
Identities = 169/528 (32%), Positives = 278/528 (52%), Gaps = 25/528 (4%)
Query: 67 LYLLSL-VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRI 125
LY + L +AQ+ + T G+ + + +R++ IL+ N+ FF G++ +RI
Sbjct: 32 LYFVYLGIAQFILLYVSTVGFIYVGEHITQKIRAKYLHAILRQNIGFFDKLGAGEVTTRI 91
Query: 126 INDTNVVNDVLVSGLLGGLG-SILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGG 184
DTN++ D G+ +G ++ +L+ A ++ V+ + L +V + L GG
Sbjct: 92 TADTNLIQD----GISEKVGLTLTALSTFFSAFIIGYVRYWKLALICSSTIVAMILVMGG 147
Query: 185 KMRRAYRETRQKIAKIS---SVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRV 241
R + R + +V EE ++ I AFG ++ + +++ E K R+
Sbjct: 148 ISRFVVKSGRMTLVSYGEGGTVAEEVISSIRNATAFGTQEKLARQYEVHLKEARKWGRRL 207
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
+ +GI + M + + G G + +V + I NV
Sbjct: 208 QMMLGIMFGSMMAIMYSNYGLGFWMGSRFLVGGETDLSAIVNILLAIVIGSFSIGNVAPN 267
Query: 302 YDSLQSALAALERIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VL 355
+ SA++A +I+ +D + D EG ++E ++G IEFR + Y RP V+
Sbjct: 268 TQAFASAISAGAKIFSTIDRVSAIDPGSDEGDTIENVEGTIEFRGIKHIYPS-RPEVVVM 326
Query: 356 KDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI 415
+D+NL +P A+VG +G+GK+T+ L+ RFY+P G +L DG D K ++ + LR++I
Sbjct: 327 EDINLVVPKGKTTALVGPSGSGKSTVVGLLERFYNPVSGSVLLDGRDIKTLNLRWLRQQI 386
Query: 416 GYVPQETYLFPGTIMENI---LMANPEAKE------EDVIRVCKELGIHDFIMKLPKGYE 466
V QE LF TI ENI L+ +P E E ++ KE HDFIM LP GY
Sbjct: 387 SLVSQEPTLFGTTIFENIRLGLIGSPMENESEEQIKERIVSAAKEANAHDFIMGLPDGYA 446
Query: 467 TSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRT 526
T G+ G LLS G++Q I++ARA++ DP I++LDEA S++D K+E +VQ A+ GRT
Sbjct: 447 TDVGQRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSALDTKSEGVVQAALDAASRGRT 506
Query: 527 SIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+I+IAHRLS + AD ++V+ GRI E+G+ EL+ +KG + +L +Q
Sbjct: 507 TIVIAHRLSTIKSADNIVVIVGGRIAEQGTHDELVDKKGTYLQLVEAQ 554
Score = 253 bits (640), Expect = 3e-66
Identities = 159/533 (29%), Positives = 282/533 (52%), Gaps = 19/533 (3%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--K 116
++ F ++++L+ + Q + Q + + ++ RS+ +L+ ++ FF
Sbjct: 687 EDANFWSLMFLMLGLVQLVTQSAQGVIFAICSESLIYRARSKSFRAMLRQDIAFFDLPEN 746
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGG-LGSILSLAGIIVAMLLLDV----KLTLVTLTS 171
STG L S + +T + SG+ G LG+IL ++ ++ L + + KL LV +++
Sbjct: 747 STGALTSFLSTETKHL-----SGVSGATLGTILMVSTTLIVALTVALAFGWKLALVCIST 801
Query: 172 VPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVS 231
VP++++ Y + + ++ +S E+ + I T+ + +E+ V + +
Sbjct: 802 VPVLLLCGFYRFWILAQFQTRAKKAYESSASYACEATSSIRTVASLTREQGVMEIYEGQL 861
Query: 232 TETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKG---AVSIGVVVAFIQYA 288
+ K LR + + S + + YGG L KG A + ++ + +
Sbjct: 862 NDQAKKSLRSVAKSSLLYAASQSFSFFCLALGFWYGGGLLGKGEYNAFQFFLCISCVIFG 921
Query: 289 QRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEY 348
+ G + + +SA A +R+++ + ++E +G +E ++G IEFR+V F Y
Sbjct: 922 SQSAGIVFSFSPDMGKAKSAAADFKRLFDRVPTIDIESTDGEKLETVEGTIEFRDVHFRY 981
Query: 349 --EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKI 406
+PVL+ +NL + P +A+VG +G GK+T L+ RFYD G + DG D ++
Sbjct: 982 PTRPEQPVLRGLNLTVKPGQYIALVGPSGCGKSTTIALVERFYDTLSGGVYIDGKDISRL 1041
Query: 407 SRKSLRKRIGYVPQETYLFPGTIMENILMA--NPEAKEEDVIRVCKELGIHDFIMKLPKG 464
+ S R + V QE L+ GTI +N+L+ + +E V CK I+DFIM LP G
Sbjct: 1042 NVNSYRSHLALVSQEPTLYQGTIRDNVLLGVDRDDVPDEQVFAACKAANIYDFIMSLPDG 1101
Query: 465 YETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEG 524
+ T G G +LS G++Q I++ARA+++DP +++LDEA S++D ++E++VQ A+ +G
Sbjct: 1102 FGTVVGSKGSMLSGGQKQRIAIARALIRDPKVLLLDEATSALDSESEKVVQAALDAAAKG 1161
Query: 525 RTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
RT+I +AHRLS + AD + V D GRIVE G+ ELL KG +Y+L Q E
Sbjct: 1162 RTTIAVAHRLSTIQKADIIYVFDQGRIVESGTHHELLQNKGRYYELVHMQSLE 1214
>dbj|BAB02129.1| (AP000386) P-glycoprotein; multi-drug resistance related; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1252
Score = 257 bits (650), Expect = 2e-67
Identities = 165/529 (31%), Positives = 276/529 (51%), Gaps = 24/529 (4%)
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS-TG 119
LG + + +A W ++ G++ + LR + E +L+ ++ FF T + TG
Sbjct: 93 LGLVVCFSSYAEIACWMYS----------GERQVAALRKKYLEAVLKQDVGFFDTDARTG 142
Query: 120 DLVSRIINDTNVVNDVLVSGLLGGLGSILS--LAGIIVAMLLLDVKLTLVTLTSVPLMVI 177
D+V + DT +V D +S +G LS LAG++V + KL L+++ +P +
Sbjct: 143 DIVFSVSTDTLLVQDA-ISEKVGNFIHYLSTFLAGLVVGFVSA-WKLALLSVAVIPGIAF 200
Query: 178 IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKA 237
+ + ++R+ A + E+++A + T+ ++ E +S T+K
Sbjct: 201 AGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALNAYSDAIQYTLKL 260
Query: 238 YLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINN 297
+ + G+ + +S +V Y G G G I A +
Sbjct: 261 GYKAGMAKGLGLGCTYGIACMSWALVFWYAGVFIRNGQTDGGKAFTAIFSAIVGGMSLGQ 320
Query: 298 VVSMYDSLQSALAALERIYEILDDENV---EDYEGISVEKLKGEIEFRNVWFEYEKGRP- 353
S + AA ++ EI++ + +G ++++ G IEF++V F Y RP
Sbjct: 321 SFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHGNIEFKDVTFSYPS-RPD 379
Query: 354 --VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
+ ++ N++ P VA+VG +G+GK+T+ +LI RFYDP G+IL DG++ K + K L
Sbjct: 380 VMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQILLDGVEIKTLQLKFL 439
Query: 412 RKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
R++IG V QE LF TI+ENIL P+A +V H FI LPKGY+T GE
Sbjct: 440 REQIGLVNQEPALFATTILENILYGKPDATMVEVEAAASAANAHSFITLLPKGYDTQVGE 499
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G LS G++Q I++ARAMLKDP I++LDEA S++D +E +VQ A+ ++M GRT++++A
Sbjct: 500 RGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQEALDRVMVGRTTVVVA 559
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
HRL R D + V+ G++VE G+ EL+++ G + L + QE+ G
Sbjct: 560 HRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLI--RFQEMVG 606
Score = 254 bits (642), Expect = 2e-66
Identities = 170/569 (29%), Positives = 291/569 (50%), Gaps = 22/569 (3%)
Query: 28 VVSIVGSALANLASPYILRVA---------IDHYIIPGRYKELGFIAMLYLLSLVAQWFF 78
++ VGS L+ P V D+ + + KE FI + L V +
Sbjct: 688 IMGAVGSILSGFIGPTFAIVMSNMIEVFYYTDYDSMERKTKEYVFIYIGAGLYAVGAYL- 746
Query: 79 TTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD--LVSRIINDTNVVNDVL 136
+Q ++ + G+ + +R + IL++ + +F + +R+ D V +
Sbjct: 747 --IQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDEHNSSLIAARLATDAADVKSAI 804
Query: 137 VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
+ L ++ SL + +++ +++L+ L + PL+V+ ++ +T +
Sbjct: 805 AERISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLLVLANFAQQLSLKGFAGDTAKA 864
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
AK S + E V+ I T+ AF + + F K L + G + L +A
Sbjct: 865 HAKTSMIAGEGVSNIRTVAAFNAQSKILSLFCHELRVPQKRSLYRSQTSGFLFGLSQLAL 924
Query: 257 LLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
S +++ YG +L KG + V+ + VS+ + A+ ++
Sbjct: 925 YGSEALILWYGAHLVSKGVSTFSKVIKVFVVLVITANSVAETVSLAPEIIRGGEAVGSVF 984
Query: 317 EILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAI 370
+LD + + +D + VE ++G+IEFR+V F Y RP V +D NL I A+
Sbjct: 985 SVLDRQTRIDPDDADADPVETIRGDIEFRHVDFAYPS-RPDVMVFRDFNLRIRAGHSQAL 1043
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG +G+GK+++ +I RFYDP G+++ DG D ++++ KSLR +IG V QE LF TI
Sbjct: 1044 VGASGSGKSSVIAMIERFYDPLAGKVMIDGKDIRRLNLKSLRLKIGLVQQEPALFAATIF 1103
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI A E +VI + H FI LP+GY+T GE G LS G++Q I++ARA+
Sbjct: 1104 DNIAYGKDGATESEVIDAARAANAHGFISGLPEGYKTPVGERGVQLSGGQKQRIAIARAV 1163
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
LK+P +++LDEA S++D ++E ++Q A+ +LM GRT++++AHRLS R D + V+ DGR
Sbjct: 1164 LKNPTVLLLDEATSALDAESECVLQEALERLMRGRTTVVVAHRLSTIRGVDCIGVIQDGR 1223
Query: 551 IVEEGSPGELLSR-KGYFYKLYTSQMQEV 578
IVE+GS EL+SR +G + +L Q +
Sbjct: 1224 IVEQGSHSELVSRPEGAYSRLLQLQTHRI 1252
>pir||A35391 hetA protein - Anabaena sp
Length = 607
Score = 257 bits (649), Expect = 3e-67
Identities = 170/538 (31%), Positives = 285/538 (52%), Gaps = 16/538 (2%)
Query: 47 VAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKIL 106
+A D + IP Y+ I++L LLS + F YTE + L Q+ E++
Sbjct: 78 LAADAWPIPPIYR----ISLLILLSTWMRATFNYFGGVYTESAQLNLADRLHKQIFEQLQ 133
Query: 107 QSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTL 166
L +F +G+L++ I + + SGL L I+++ V M + +L++
Sbjct: 134 ALRLSYFAQTRSGELINTITTEIERIKQGF-SGLAFVLTRIMTVCVYFVVMFSISWQLSI 192
Query: 167 VTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKE 226
+++ L+ + ++R A+ ++V E + GI TI+AFG ++ +
Sbjct: 193 ISVLIFLLLAVGLSTLNKRVRETSFGISHANAQFTAVAVEFINGIRTIQAFGTQEFERQR 252
Query: 227 FSKVSTETIKAYLRVAIYMGIFWPLMN--IASLLSVIVVIAYGGYLAYKGAVSIGVVVAF 284
F K ST + A ++V + + P+ ++L ++VI++ + + + ++ F
Sbjct: 253 FYKASTNQLNAAIKVVLAWTLVKPIAEGIATTVLISLIVISFATF-----TLPVASLLTF 307
Query: 285 IQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEG--ISVEKLKGEIEFR 342
R I ++ L + + E I IL N + + + LK I+
Sbjct: 308 FFVLVRVIPNIQDINGTVAFLSTLQGSSENIKNILQTNNKPYLKNGKLHFQGLKRSIDLV 367
Query: 343 NVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGID 402
+V F Y VL ++ L I A+VG +GAGKTT+A+LI RFYDPT+G+IL DG+D
Sbjct: 368 SVDFGYTADNLVLNNITLTIERGKTTALVGASGAGKTTLADLIPRFYDPTEGQILVDGLD 427
Query: 403 GKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLP 462
+ SLR+++ V Q+T++F +I +NI A E ++ V + FI ++P
Sbjct: 428 VQYFEINSLRRKMAVVSQDTFIFNTSIRDNIAYGTSGASEAEIREVARLANALQFIEEMP 487
Query: 463 KGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLM 522
+G++T G+ G LS G+RQ I++ARA+L+DP+I+ILDEA S++D +E+L+Q ++ KL
Sbjct: 488 EGFDTKLGDRGVRLSGGQRQRIAIARALLRDPEILILDEATSALDSVSERLIQESIEKLS 547
Query: 523 EGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
GRT I IAHRLS ADKV+V++ GRIVE+G+ ELL ++G +K + QMQ G
Sbjct: 548 VGRTVIAIAHRLSTIAKADKVVVMEQGRIVEQGNYQELLEQRGKLWKYH--QMQHESG 603
>sp|P22638|HEPA_ANASP HETEROCYST DIFFERENTIATION ATP-BINDING PROTEIN HEPA
>gi|2625135|gb|AAC32400.1| (AF031959) heterocyst
differentiation protein [Anabaena PCC7120]
Length = 532
Score = 257 bits (649), Expect = 3e-67
Identities = 170/538 (31%), Positives = 285/538 (52%), Gaps = 16/538 (2%)
Query: 47 VAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKIL 106
+A D + IP Y+ I++L LLS + F YTE + L Q+ E++
Sbjct: 3 LAADAWPIPPIYR----ISLLILLSTWMRATFNYFGGVYTESAQLNLADRLHKQIFEQLQ 58
Query: 107 QSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTL 166
L +F +G+L++ I + + SGL L I+++ V M + +L++
Sbjct: 59 ALRLSYFAQTRSGELINTITTEIERIKQGF-SGLAFVLTRIMTVCVYFVVMFSISWQLSI 117
Query: 167 VTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKE 226
+++ L+ + ++R A+ ++V E + GI TI+AFG ++ +
Sbjct: 118 ISVLIFLLLAVGLSTLNKRVRETSFGISHANAQFTAVAVEFINGIRTIQAFGTQEFERQR 177
Query: 227 FSKVSTETIKAYLRVAIYMGIFWPLMN--IASLLSVIVVIAYGGYLAYKGAVSIGVVVAF 284
F K ST + A ++V + + P+ ++L ++VI++ + + + ++ F
Sbjct: 178 FYKASTNQLNAAIKVVLAWTLVKPIAEGIATTVLISLIVISFATF-----TLPVASLLTF 232
Query: 285 IQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEG--ISVEKLKGEIEFR 342
R I ++ L + + E I IL N + + + LK I+
Sbjct: 233 FFVLVRVIPNIQDINGTVAFLSTLQGSSENIKNILQTNNKPYLKNGKLHFQGLKRSIDLV 292
Query: 343 NVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGID 402
+V F Y VL ++ L I A+VG +GAGKTT+A+LI RFYDPT+G+IL DG+D
Sbjct: 293 SVDFGYTADNLVLNNITLTIERGKTTALVGASGAGKTTLADLIPRFYDPTEGQILVDGLD 352
Query: 403 GKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLP 462
+ SLR+++ V Q+T++F +I +NI A E ++ V + FI ++P
Sbjct: 353 VQYFEINSLRRKMAVVSQDTFIFNTSIRDNIAYGTSGASEAEIREVARLANALQFIEEMP 412
Query: 463 KGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLM 522
+G++T G+ G LS G+RQ I++ARA+L+DP+I+ILDEA S++D +E+L+Q ++ KL
Sbjct: 413 EGFDTKLGDRGVRLSGGQRQRIAIARALLRDPEILILDEATSALDSVSERLIQESIEKLS 472
Query: 523 EGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
GRT I IAHRLS ADKV+V++ GRIVE+G+ ELL ++G +K + QMQ G
Sbjct: 473 VGRTVIAIAHRLSTIAKADKVVVMEQGRIVEQGNYQELLEQRGKLWKYH--QMQHESG 528
>gb|AAB88657.1| (U62933) multidrug resistance protein 1 [Aspergillus fumigatus]
>gi|2673953|gb|AAB88658.1| (U62934) multidrug resistance
protein 1 [Aspergillus fumigatus]
Length = 1349
Score = 257 bits (649), Expect = 3e-67
Identities = 178/597 (29%), Positives = 312/597 (51%), Gaps = 35/597 (5%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASP---YILRVAIDHYIIPGRY- 58
+K SL L +FI R L +++ + S LA P ++ AI +P
Sbjct: 757 EKYSLWTLVKFI--GAFNRPELGYMLIGLTFSFLAGGGQPTQAFLYAKAISTLSLPESMF 814
Query: 59 ----KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF- 113
+ F ++++ + +AQ+ ++ + ++++R RSQ IL+ ++ FF
Sbjct: 815 HKLRHDANFWSLMFFVVGIAQFISLSINGTAFAICSERLIRRARSQAFRSILRQDISFFD 874
Query: 114 -KTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSIL----SLAGIIVAMLLLDVKLTLVT 168
+ STG L S + +T ++ V SG+ LG+I+ +L ++ L + KL LV
Sbjct: 875 REENSTGALTSFLSTETKNLSGV--SGVT--LGTIIMTSTTLGAAMIIALAIGWKLALVC 930
Query: 169 LTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDV----E 224
++ VP+++ + + + ++ +S E+ + I T+ + +E+DV
Sbjct: 931 ISVVPILLACGFLRFYMLAQFQQRSKSAYEGSASYACEATSAIRTVASLTREQDVWGVYH 990
Query: 225 KEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIG---VV 281
+ K +++ + LR ++ L+ V + YGG L SI V
Sbjct: 991 DQLQKQGRKSLISVLRSSLLYASSQALV----FFCVALGFWYGGTLLGHHEYSIFRFFVC 1046
Query: 282 VAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEF 341
+ I + + G + + ++A A +++++ ++ EG +E ++GEIEF
Sbjct: 1047 FSEILFGAQSAGTVFSFAPDMGKAKNAAAQFKKLFDSKPTIDIWSDEGEKLESMEGEIEF 1106
Query: 342 RNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYD 399
R+V F Y +PVL+ +NL + P +A+VG +G GK+T L+ RFYD G + D
Sbjct: 1107 RDVHFRYPTRPEQPVLRGLNLSVKPGQYIALVGPSGCGKSTTIALLERFYDALAGGVFVD 1166
Query: 400 GIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMA--NPEAKEEDVIRVCKELGIHDF 457
G D K++ S R + V QE L+ GTI ENIL+ + EE +I+VCK+ I+DF
Sbjct: 1167 GKDITKLNVNSYRSFLSLVSQEPTLYQGTIKENILLGVDKDDVSEETLIKVCKDANIYDF 1226
Query: 458 IMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNA 517
+M LP+G++T G G +LS G++Q +++ARA+L+DP +++LDEA S++D ++E++VQ A
Sbjct: 1227 VMSLPEGFDTVVGSKGGMLSGGQKQRVAIARALLRDPKVLLLDEATSALDSESEKVVQAA 1286
Query: 518 MIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+ GRT+I +AHRLS + AD + V D G+IVE G+ EL+ KG +Y+L Q
Sbjct: 1287 LDAAARGRTTIAVAHRLSTIQNADIIYVFDQGKIVESGTHHELIRNKGRYYELVNLQ 1343
Score = 249 bits (628), Expect = 9e-65
Identities = 165/516 (31%), Positives = 274/516 (52%), Gaps = 25/516 (4%)
Query: 77 FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVL 136
+ +T+ YT G+ + + +R E IL+ N+ +F G++ +RI DTN++ D +
Sbjct: 175 YVSTVGFIYT---GEHLTQKIRENYLEAILRQNMAYFDKLGAGEVTTRITADTNLIQDAI 231
Query: 137 VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
+ GL ++ + A + A ++ VK + L +V + + GG R + +++
Sbjct: 232 SEKV--GL-TLTAFATFVTAFIVAYVKYWKLALICTSTIVALVMVMGGGSRFIVKYSKKS 288
Query: 197 IAKISS---VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMN 253
I + V EE ++ I AFG + + K++ E K ++ + +G+ M
Sbjct: 289 IESYGAGGTVAEEVISSIRNATAFGTQDKLAKQYETHLAEAEKWGVKQQVILGMMIGGMF 348
Query: 254 IASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALE 313
+ + G V++G V+ + + NV + + +AA
Sbjct: 349 GIMFSNYGLGFWMGSRFVVGKEVNVGQVLTVLMSILIGSFSLGNVAPNGQAFTNGVAAAA 408
Query: 314 RIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASK 367
+IY +D + D EG ++ +G IEFRNV Y RP V++DV+L +P
Sbjct: 409 KIYSTIDRRSPLDPYSDEGKVLDHFEGNIEFRNVKHIYPS-RPEVTVMEDVSLSMPAGKT 467
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
A+VG +G+GK+T+ L+ RFY P G++L DG D + ++ + LR++I V QE LF
Sbjct: 468 TALVGPSGSGKSTVVGLVERFYLPVGGQVLLDGHDIQTLNLRWLRQQISLVSQEPVLFST 527
Query: 428 TIMENI----LMANPEAKEEDVIRVCKE-----LGIHDFIMKLPKGYETSAGEAGKLLSV 478
TI NI + E + +D IR E HDFIM LP+GY+T+ G+ G LLS
Sbjct: 528 TIFRNIEHGLIGTKFEHESKDKIRELVENAARMANAHDFIMALPEGYDTNVGQRGFLLSG 587
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G++Q I++ARA++ DP I++LDEA S++D K+E +VQ A+ K EGRT+I+IAHRLS +
Sbjct: 588 GQKQRIAIARAIVSDPKILLLDEATSALDTKSEGVVQAALDKAAEGRTTIVIAHRLSTIK 647
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
A ++ + G+I E+G+ EL+ RKG +YKL +Q
Sbjct: 648 TAHNIVAMVGGKIAEQGTHDELVDRKGTYYKLVEAQ 683
>gb|AAF23176.1|AF216497_1 (AF216497) P-glycoprotein [Gossypium hirsutum]
Length = 1249
Score = 257 bits (649), Expect = 3e-67
Identities = 165/535 (30%), Positives = 287/535 (52%), Gaps = 28/535 (5%)
Query: 60 ELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFK--TKS 117
E+ IA+L+ + V ++ + G+++ +R + IL++ + +F +
Sbjct: 722 EVKKIAILFCCASVITVIVHAIEHLCFGIMGERLTLRVREGMFSAILKNEIGWFDDLNNA 781
Query: 118 TGDLVSRIINDTNVVNDVLV---SGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPL 174
+ L SR+ D + V+V S L+ +G L +A I+A +L + ++TL+ L + PL
Sbjct: 782 SSMLASRLETDATFLRGVVVDRTSILIQNVG--LVIAAFIIAFIL-NWRITLIILATFPL 838
Query: 175 MV-------IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEF 227
++ + +GG + +AY K + + E+V+ + T+ AF E+ + +
Sbjct: 839 IISGHISEKLFMQGYGGNLSKAY-------LKANMIAGEAVSNMRTVAAFCAEEKILDLY 891
Query: 228 SKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQY 287
++ E + + GIF+ + S + + YG L K S V+
Sbjct: 892 ARELIEPSERSFKRGQIAGIFYGISQFFIFSSYGLALWYGSVLMGKELASFKSVMKSFMV 951
Query: 288 AQRFRGPINNVVSMYDSLQSALAALERIYEILDDEN-VEDYEGISVEKLKGEIEFRNVWF 346
+ +++ L + ++EI+D + V G + ++G IE + V F
Sbjct: 952 LIVTALAMGETLALVPDLLKGNQMVASVFEIMDRKTQVVGDAGEELTNVEGTIELKGVHF 1011
Query: 347 EYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDG 403
Y RP + KD +L + +A+VG++G+GK+++ LI+RFYDPT G+++ DG D
Sbjct: 1012 SYPS-RPDVVIFKDFDLKVRSGKSMALVGQSGSGKSSVLALILRFYDPTSGKVMIDGRDV 1070
Query: 404 KKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPK 463
KK+ KSLRK IG V QE LF +I ENIL A E +V+ K H FI LP+
Sbjct: 1071 KKLKLKSLRKHIGLVQQEPALFATSIYENILYGKEGASESEVVEAAKLANAHSFISSLPE 1130
Query: 464 GYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME 523
GY T GE G LS G++Q +++ARA+LK+P+I++LDEA S++D ++E++VQ A+ +LM
Sbjct: 1131 GYSTKVGERGVQLSGGQKQRVAIARAVLKNPEILLLDEATSALDVESERVVQQALDRLMR 1190
Query: 524 GRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELL-SRKGYFYKLYTSQMQE 577
RT++++AHRLS + AD++ V+ GRI+E+G+ L+ +R G ++KL Q Q+
Sbjct: 1191 NRTTVMVAHRLSTIKNADRISVIQGGRIIEQGTHSSLIENRNGPYFKLINLQQQQ 1245
Score = 228 bits (575), Expect = 1e-58
Identities = 159/508 (31%), Positives = 259/508 (50%), Gaps = 30/508 (5%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKTK-STGDLVSRIINDTNVVNDVLVSGLLGGLGSIL 148
G++ +R + +L ++ F T+ STG+++S I +D VV D L S +G +
Sbjct: 116 GERQAAKMRMAYLKSMLNQDISLFDTEASTGEVISAITSDIIVVQDAL-SEKVGNFMHYI 174
Query: 149 S--LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEE 206
S +AG + + +++LVTL+ VPL+ + + R K + EE
Sbjct: 175 SRFIAGFSIGFARV-WQISLVTLSIVPLIALAGGIYAYVATGLIARVRNSYVKAGEIAEE 233
Query: 207 SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAY 266
+ + T++AF E+ K + T + + G+ ++ +S +++ +
Sbjct: 234 VIGNVRTVQAFAGEERAVKSYKDALMNTYTYGKKAGLTKGLGLGSLHCVLFVSWALLVWF 293
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSA---------LAALERIYE 317
+ +K + G F +N V+S Q+A AA I+E
Sbjct: 294 TSIVVHKNIANGG---------DSFTTMLNVVISGLSLGQAAPDISAFIRARAAAYPIFE 344
Query: 318 ILDDENVEDYE---GISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIV 371
+++ V G + K++G IE +NV F Y RP + L IP VA+V
Sbjct: 345 MIERNTVSKTSSKTGRKLSKVEGNIELKNVSFSYPS-RPDVVIFDRFCLNIPTGKIVALV 403
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G +G+GK+T+ +LI RFY+P GEIL DG + K + K LR++IG V QE LF TI E
Sbjct: 404 GGSGSGKSTVISLIERFYEPLAGEILLDGNNIKGLDLKWLRQQIGLVNQEPALFATTIRE 463
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NIL +A +++ R K FI LP +ET GE G LS G++Q I+++RA++
Sbjct: 464 NILYGKDDATVDEITRAAKLSEAIAFINNLPDRFETQVGERGIQLSGGQKQRIAISRAIV 523
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
K+P I++LDEA S++D ++E+ VQ A+ ++M GRT++++AHRLS R AD + VV +G+I
Sbjct: 524 KNPPILLLDEATSALDAESEKSVQEALDRVMVGRTTVVVAHRLSTIRNADVIAVVQNGKI 583
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQEVP 579
VE G+ EL+S Y + P
Sbjct: 584 VETGTHDELISNPNSTYSSLVQHQETSP 611
>pir||T40790 probable permease - fission yeast (Schizosaccharomyces pombe)
>gi|4760347|emb|CAB42370.1| (AL049769) putative permease
[Schizosaccharomyces pombe]
Length = 726
Score = 256 bits (648), Expect = 4e-67
Identities = 170/524 (32%), Positives = 274/524 (51%), Gaps = 12/524 (2%)
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
+I +L L L + F + T + ++++ LR++L K + + FF GDL+
Sbjct: 205 YIGLLGLFFLGSACNFGRIITL--RLLSERIVSRLRARLFAKCMSLDGAFFDFHKHGDLI 262
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
SR+ D+++V L L GL S +S I ML + ++LT VP + + A ++
Sbjct: 263 SRLTTDSSIVGKSLSMYLSDGLRSSVSAIAGIGMMLYVSMRLTGYMSLIVPPIALGAFFY 322
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
G +R+ R T+ + ++ V EE +A + T +AF E+ ++ R A
Sbjct: 323 GEYVRKLSRTTQDALGDLTRVSEEKLANVRTTQAFLGERQEVNRYNDYIRNLFVLAKREA 382
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
GIF+ +VI ++A GG + G +++G + +F+ Y G I + +
Sbjct: 383 FASGIFFGSTGFLGNATVIAILALGGRMVAAGDITVGQLSSFLLYTVYAGGSIVGLSGCF 442
Query: 303 DSLQSALAALERIYEILDDE-NVEDYEGISVEKLKGE--IEFRNVWFEY--EKGRPVLKD 357
+ L A R++E+LD + + GI V G+ + FRNV F Y + +
Sbjct: 443 TDIMKGLGAASRLFELLDAKPKIAPTVGIPVPVTVGKAILSFRNVGFAYPTRPSASIFDN 502
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
++ I P + VAIV +G GK+TI+ L++RFY P+ G+IL DG+D + R G
Sbjct: 503 LSFDIHPGTNVAIVAPSGGGKSTISQLLLRFYAPSSGKILADGVDISTYNVHQWRSHFGL 562
Query: 418 VPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLS 477
V QE LF GTI ENI A +E++ K F++ P+ + T G G LS
Sbjct: 563 VGQEPVLFSGTIGENIAYGKSNASQEEIEDAAKRANC-SFVLSFPEKWSTQVGTRGLQLS 621
Query: 478 VGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGR--TSIIIAHRLS 535
G++Q I++ARA+L++P +ILDEA S++D + E +V + LM R T+I IAH+L+
Sbjct: 622 GGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNRSMTTITIAHKLA 681
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSRKG-YFYKLYTSQMQEV 578
R AD++IVV DG+++E+GS E LSR G FYKL Q+ +V
Sbjct: 682 TIRRADQIIVVGDGKVLEQGS-FERLSRPGTNFYKLMRWQLGKV 724
>gi|11038656 ATP-binding cassette, sub-family B, member 11; bile salt export
pump [Mus musculus] >gi|6502606|gb|AAF14372.1|AF133903_1
(AF133903) liver bile salt export pump;
sister-of-p-glycoprotein [Mus musculus domesticus]
Length = 1321
Score = 256 bits (648), Expect = 4e-67
Identities = 160/497 (32%), Positives = 258/497 (51%), Gaps = 8/497 (1%)
Query: 88 VFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
+ G + +R +R +I++ + +F S G+L SR +D N +++ + + L +
Sbjct: 165 ITGARQIRKMRKFYFRRIMRMEIGWFDCTSVGELNSRFSDDINKIDEAIADQMALFLQRL 224
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEES 207
+ ++ KLTLV L PL+ I A G + + + AK S+ +E
Sbjct: 225 STALSGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSVAKFTELELKAYAKAGSIADEV 284
Query: 208 VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
++ I T+ AFG E + + K + + + MG F M + YG
Sbjct: 285 LSSIRTVAAFGGENKEVERYEKNLMFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYG 344
Query: 268 GYLAY-KGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVED 326
L +G + G ++ I N S + + +A I++ +D + V D
Sbjct: 345 SRLVLDEGEYTPGTLIQIFLCVIIAAMNIGNASSCLEIFSTGCSAASSIFQTIDRQPVMD 404
Query: 327 Y---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTT 380
+G ++++KGEIEF NV F Y RP +L ++++ I P A VG +GAGK+T
Sbjct: 405 CMSGDGYKLDRIKGEIEFHNVTFHYPS-RPEVKILNNLSMVIKPGETTAFVGSSGAGKST 463
Query: 381 IANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEA 440
LI RFYDP +G + DG D + ++ + LR +IG V QE LF TI ENI + EA
Sbjct: 464 ALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRLGREEA 523
Query: 441 KEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILD 500
ED+++ K+ ++FIM LP+ ++T GE G +S G++Q +++ARA+++ P I++LD
Sbjct: 524 TMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRKPKILLLD 583
Query: 501 EALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGEL 560
A S++D ++E VQ A+ K+ G T I +AHRLS R AD +I + G VE G+ EL
Sbjct: 584 MATSALDNESEAKVQGALNKIQHGHTIISVAHRLSTVRSADVIIGFEHGTAVERGTHEEL 643
Query: 561 LSRKGYFYKLYTSQMQE 577
L RKG ++ L T Q QE
Sbjct: 644 LERKGVYFMLVTLQSQE 660
Score = 233 bits (587), Expect = 6e-60
Identities = 155/518 (29%), Positives = 263/518 (49%), Gaps = 15/518 (2%)
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGD 120
F +L +SL Q+ LQ + G+ + + LR + +L+ ++ +F + G
Sbjct: 801 FFVILGCVSLFTQF----LQGYNFAKSGELLTKRLRKFGFKAMLRQDIGWFDDLKNNPGV 856
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L +R+ D + V S + + S ++ ++ L + KL+LV P + +
Sbjct: 857 LTTRLATDASQVQGATGSQVGMMVNSFTNIFVAVLIAFLFNWKLSLVISVFFPFLALSGA 916
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+ + ++ + K + E+++ I T+ G E K F ++ K +R
Sbjct: 917 VQTKMLTGFASQDKEILEKAGQITNEALSNIRTVAGIGVEGRFIKAFEVELEKSYKTAIR 976
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
A G+ + S L+ YGGYL ++ V + + S
Sbjct: 977 KANVYGLCYAFSQGISFLANSAAYRYGGYLIVYEDLNFSYVFRVVSSIAMSATAVGRTFS 1036
Query: 301 MYDSLQSALAALERIYEILDDEN-VEDYEGISV--EKLKGEIEFRNVWFEYEKGRP---V 354
S A + R +++LD + ++ Y G + +G+I+F + F Y RP V
Sbjct: 1037 YTPSYAKAKISAARFFQLLDRKPPIDVYSGAGEKWDNFQGKIDFIDCKFTYPS-RPDIQV 1095
Query: 355 LKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKR 414
L +++ + P +A VG +G GK+T L+ RFYDP +G ++ DG D KK++ + LR
Sbjct: 1096 LNGLSVSVDPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNVQFLRSN 1155
Query: 415 IGYVPQETYLFPGTIMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEA 472
IG V QE LF +IM+NI + E E I K+ +HDF+M LP+ YET+ G
Sbjct: 1156 IGIVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQ 1215
Query: 473 GKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAH 532
G LS GE+Q I++ARA+++DP I++LDEA S++D ++E+ VQ A+ K EGRT I+IAH
Sbjct: 1216 GSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQLALDKAREGRTCIVIAH 1275
Query: 533 RLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
RLS + +D + V+ G ++E+G+ +L+ +KG +YKL
Sbjct: 1276 RLSTIQNSDIIAVMSQGVVIEKGTHKKLMDQKGAYYKL 1313
>dbj|BAB02852.1| (AB026644) multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1228
Score = 256 bits (648), Expect = 4e-67
Identities = 166/529 (31%), Positives = 284/529 (53%), Gaps = 26/529 (4%)
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFK--TKSTGDL 121
+AMLY+ A W L+ + G++ +R + +L+ ++ +F ST D+
Sbjct: 69 LAMLYVAC--ASWVICFLEGYCWTRTGERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDI 126
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALY 181
++ + +D+ V+ D L L L + + G + +L +LT+V + L++I L
Sbjct: 127 ITSVSSDSLVIQDFLSEKLPNILMNASAFVGSYIVGFMLLWRLTIVGFPFIILLLIPGLM 186
Query: 182 FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRV 241
+G + R+ R++ + S+ E++++ + T+ AF EK + ++FS ++K LR
Sbjct: 187 YGRALIGISRKIREEYNEAGSIAEQAISSVRTVYAFVSEKKMIEKFSDALQGSVKLGLRQ 246
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSI------GVVVAFIQYAQRFRGP- 294
+ GI ++ S +V A G+L + G+ + G V+ + F G
Sbjct: 247 GLAKGI--------AIGSNGIVYAIWGFLTWYGSRMVMNYGYKGGTVSTVTVCVTFGGTA 298
Query: 295 INNVVSMYDSLQSALAALERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEYEKG 351
+ +S A A ERI +++ D + ++ G +E ++GE+EF NV +Y
Sbjct: 299 LGQALSNLKYFSEAFVAGERIQKMIKRVPDIDSDNLNGHILETIRGEVEFNNVKCKYPS- 357
Query: 352 RP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISR 408
RP + D+ L IP VA+VG +G+GK+T+ +L+ RFYDP +G+IL D + +
Sbjct: 358 RPETLIFDDLCLKIPSGKTVALVGGSGSGKSTVISLLQRFYDPNEGDILIDSVSINNMQV 417
Query: 409 KSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETS 468
K LR ++G V QE LF +I ENIL +A ++V+ K H+FI + P GY+T
Sbjct: 418 KWLRSQMGMVSQEPSLFATSIKENILFGKEDASFDEVVEAAKASNAHNFISQFPHGYQTQ 477
Query: 469 AGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSI 528
GE G +S G++Q I++ARA++K P I++LDEA S++D ++E++VQ A+ GRT+I
Sbjct: 478 VGERGVHMSGGQKQRIAIARALIKSPIILLLDEATSALDLESERVVQEALDNASVGRTTI 537
Query: 529 IIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
+IAHRLS R AD + V+ +G IVE GS +L+ G + L Q +
Sbjct: 538 VIAHRLSTIRNADIICVLHNGCIVETGSHDKLMEIDGKYTSLVRLQQMK 586
Score = 229 bits (577), Expect = 8e-59
Identities = 174/544 (31%), Positives = 284/544 (51%), Gaps = 44/544 (8%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYT-EVFGQKVLRNLRSQLHEKILQSNLDFF--KT 115
KE I +L L FFT++ Y+ G+ + + +R Q+ KIL +++F +
Sbjct: 695 KENTRIYVLLFFGLALFTFFTSISQQYSFSYMGEYLTKRIREQMLSKILTFEVNWFDEEE 754
Query: 116 KSTGDLVSRIINDTNVVNDVLVSGLLGGLGSIL--SLAGIIVAM---LLLDVKLTLVTLT 170
S+G + SR+ D NVV L+G S+L +++ ++VA L++ + T+V ++
Sbjct: 755 NSSGAICSRLAKDANVVRS-----LVGERMSLLVQTISTVMVACTIGLVIAWRFTIVMIS 809
Query: 171 SVPLMVIIALYFGGKMRRAYRETRQKIAKI-----SSVVEESVAGIETIRAFGKEKDVEK 225
P VII Y+ ++R + K A I S + E+V+ I TI F ++ + K
Sbjct: 810 VQP--VIIVCYY---IQRVLLKNMSKKAIIAQDESSKLAAEAVSNIRTITTFSSQERIMK 864
Query: 226 EFSKVST----ETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGA-VSIGV 280
+V E+ + I +G L+ S L+ YGG L G VS
Sbjct: 865 LLERVQEGPRRESARQSWLAGIMLGTTQSLITCTSALN----FWYGGKLIADGKMVSKAF 920
Query: 281 VVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENV---EDYEGISVEKLKG 337
F+ + R I +M L +++ ++ +LD E+ +G +EK+KG
Sbjct: 921 FELFLIFKTTGRA-IAEAGTMTTDLAKGSNSVDSVFTVLDRRTTIEPENPDGYILEKIKG 979
Query: 338 EIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKG 394
+I F NV F Y RP + + ++ I AIVG + +GK+T+ LI RFYDP +G
Sbjct: 980 QITFLNVDFAYPT-RPNMVIFNNFSIEIHEGKSTAIVGPSRSGKSTVIGLIERFYDPLQG 1038
Query: 395 EILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAK--EEDVIRVCKEL 452
+ DG D + +SLR+ + V QE LF GTI ENI+ K E ++I K
Sbjct: 1039 IVKIDGRDIRSYHLRSLRQHMSLVSQEPTLFAGTIRENIMYGRASNKIDESEIIEAGKTA 1098
Query: 453 GIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQ 512
H+FI L GY+T G+ G LS G++Q I++AR +LK+P I++LDEA S++D ++E+
Sbjct: 1099 NAHEFITSLSDGYDTYCGDRGVQLSGGQKQRIAIARTILKNPSILLLDEATSALDSQSER 1158
Query: 513 LVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR--KGYFYKL 570
+VQ+A+ +M G+TS++IAHRLS + D + V+D G++VE G+ LL++ G ++ L
Sbjct: 1159 VVQDALEHVMVGKTSVVIAHRLSTIQNCDTIAVLDKGKVVESGTHASLLAKGPTGSYFSL 1218
Query: 571 YTSQ 574
+ Q
Sbjct: 1219 VSLQ 1222
>pir||T30293 ABC transport protein homolog - Salmonella typhi
>gi|1698599|gb|AAB37256.1| (U62129) ATP binding cassette
(ABC) transporter homolog [Salmonella typhi]
Length = 1218
Score = 254 bits (643), Expect = 1e-66
Identities = 158/556 (28%), Positives = 284/556 (50%), Gaps = 9/556 (1%)
Query: 26 IVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFY 85
I + I + A + +L+ ID + G +G A+L L + W LQT +
Sbjct: 654 IAALLIALDSAAGVGVLVLLQRGIDSGVAAGDMSTIGICALLALCLVAIGWCCYALQTIF 713
Query: 86 TEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLG 145
+ V +R + +L+ +L + + K ++R+ D + + L +GL
Sbjct: 714 AARAAESVQHTVRLRSFSHLLRLSLPWHE-KHIDSRLTRMTVDVDSLARFLQNGLASAAT 772
Query: 146 SILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVE 205
SI+++ I AM LD L L L++VP++++ + AY + R +I K++S ++
Sbjct: 773 SIVTMVAIAAAMFWLDPILALTALSAVPVVILATWIYRRLSSPAYAQARLEIGKVNSTLQ 832
Query: 206 ESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIA 265
E V+G+ +++ G++K +S +R Y+ +++P + + + V+
Sbjct: 833 EKVSGMRVVQSHGQQKQEAARLRALSDNFRATRVRAQKYLAVYFPFLTFCTEAAYAAVLL 892
Query: 266 YGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVE 325
G +G ++ G++ AF +F GP+ + + DS Q A A+ + I +L E E
Sbjct: 893 IGATRVAEGEMTPGILAAFFLLLGQFYGPVQQLSGIVDSWQQATASGKHINALLATEETE 952
Query: 326 DYEGISVEK-LKGEIEFRNVWFEY-EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
+ E S+ G + + F Y EK +PVL +++L IPP + VA+VG++GAGK+T+
Sbjct: 953 NIEPSSITPGTGGALRLEALTFRYPEKTQPVLDNLSLTIPPGTVVAVVGRSGAGKSTLIK 1012
Query: 384 LIMRFYDPTKGEILYDG--IDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAK 441
L+ Y P G+I ID +S R++ G V Q+ LF G I ENI + P++
Sbjct: 1013 LLAGLYSPGSGQIRVGERLIDAASLS--DYRRQTGLVTQDVALFSGDIAENIRYSRPDSS 1070
Query: 442 EEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDE 501
+ +V ++ G+ + + LP G+ T G LS G+RQLI+LARA L I++LDE
Sbjct: 1071 DTEVEIAARQAGLFETVQHLPLGFRTPVNNGGTDLSAGQRQLIALARAQLAQAHILLLDE 1130
Query: 502 ALSSVDPKTEQLVQNAM--IKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGE 559
A + +D E+ + ++ + E R ++I+AHRL+ R D ++V+D G I E GS +
Sbjct: 1131 ATARIDRSAEERLITSLTGVTHTEKRIALIVAHRLTTARRCDVIVVIDKGCIAEYGSHEQ 1190
Query: 560 LLSRKGYFYKLYTSQM 575
L++ G + +L+ + +
Sbjct: 1191 LIAAHGLYARLWRASV 1206
Score = 208 bits (524), Expect = 1e-52
Identities = 130/437 (29%), Positives = 231/437 (52%), Gaps = 20/437 (4%)
Query: 150 LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRET---RQKIAKISSVVEE 206
+AGI V ML + +TL+ + + + I AL RR + +T ++A ++ + E
Sbjct: 153 VAGIAV-MLWMSPSMTLIVICVLAALAITALR---ARRRVFAQTGLASDRLAHMTEHMRE 208
Query: 207 SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAY 266
+ I +++ E + S + ++ + AI + M ++ IV++ Y
Sbjct: 209 VLEQISVVKSCVAELRETRWLDGQSRQMVRVRIGAAISQAMPGATMLALPVIGQIVLLCY 268
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDEN-VE 325
GG+ G + +G VAF + GP + S Q A++ER++ ++D + +E
Sbjct: 269 GGWSVMNGRIDLGTFVAFASFLAMLTGPTRVLASFLVIAQRTQASVERVFALIDTRSRME 328
Query: 326 DYEGISVEKLKGEI---EFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIA 382
D E ++G+I + + F Y+ G +L +++ I VA+VG +G+GK+T+
Sbjct: 329 D----GTESVEGQIIGLDVEKMSFHYDNGNRILNEISFSIHAGETVAVVGASGSGKSTLL 384
Query: 383 NLIMRFYDPTKGEILYDGIDGKKISRK----SLRKRIGYVPQETYLFPGTIMENILMANP 438
L+ RFYDPT G + + G++ R +LR+R+G V ++ +LF GT+ ENI +P
Sbjct: 385 MLLARFYDPTSGGVWLNTTTGQQNIRDLKLTALRRRVGVVFEDAFLFAGTVAENIAYGHP 444
Query: 439 EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVI 498
+A ++D+ R G FI LP+G+ T E G LS G+RQ I+LARA++ P+++I
Sbjct: 445 QATQDDIRRAADAAGASGFINALPQGFNTRLTERGSNLSGGQRQRIALARALITAPELLI 504
Query: 499 LDEALSSVDPKTEQLVQNAMIKLMEG-RTSIIIAHRLSITRFADKVIVVDDGRIVEEGSP 557
LD+ S+VD TE + A+ + + ++IA R S + AD+++V+D GR+V+ G+
Sbjct: 505 LDDTTSAVDAGTEAEINTALGRYADNEHMLLVIARRRSTLQLADRIVVLDKGRVVDIGTQ 564
Query: 558 GELLSRKGYFYKLYTSQ 574
EL +R F L + +
Sbjct: 565 AELDARCPTFRSLMSGE 581
>gb|AAD43626.1|AF071411_1 (AF071411) multidrug resistance protein MDR [Aspergillus nidulans]
>gi|6856159|gb|AAF29805.1|AF173826_1 (AF173826)
ABC-transporter [Aspergillus nidulans]
Length = 1348
Score = 254 bits (642), Expect = 2e-66
Identities = 189/594 (31%), Positives = 307/594 (50%), Gaps = 31/594 (5%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASP---YILRVAIDHYIIP-GRYK 59
K SL L +F+ A R + +++ +V S LA P + AI +P +Y
Sbjct: 757 KYSLWTLLKFV--ASFNRPEIPYMLIGLVFSVLAGGGQPTQAVLYAKAISTLSLPESQYS 814
Query: 60 EL----GFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF-- 113
+L F ++++ + + Q+ + V ++++R RS IL+ ++ FF
Sbjct: 815 KLRHDADFWSLMFFVVGIIQFITQSTNGAAFAVCSERLIRRARSTAFRTILRQDIAFFDK 874
Query: 114 KTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSIL----SLAGIIVAMLLLDVKLTLVTL 169
+ STG L S + +T ++ V SG+ LG+IL +L I+ L + KL LV +
Sbjct: 875 EENSTGALTSFLSTETKHLSGV--SGVT--LGTILMTSTTLGAAIIIALAIGWKLALVCI 930
Query: 170 TSVPLMVIIALYFGGKMRRAYRETRQKIAKISSV--VEESVAGIETIRAFGKEKDVEKEF 227
+ VP V++A F A ++R K+A S E+ + I T+ + +E+DV + +
Sbjct: 931 SVVP--VLLACGFYRFYMLAQFQSRSKLAYEGSANFACEATSSIRTVASLTRERDVWEIY 988
Query: 228 SKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIG---VVVAF 284
+ L + + + V + YGG L I V +
Sbjct: 989 HAQLDAQGRTSLISVLRSSLLYASSQALVFFCVALGFWYGGTLLGHHEYDIFRFFVCFSE 1048
Query: 285 IQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNV 344
I + + G + + ++A A R+++ + EG +E ++GEIEFRNV
Sbjct: 1049 ILFGAQSAGTVFSFAPDMGKAKNAAAEFRRLFDRKPQIDNWSEEGEKLETVEGEIEFRNV 1108
Query: 345 WFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGID 402
F Y +PVL+ ++L + P VA+VG +G GK+T L+ RFYD G IL DG D
Sbjct: 1109 HFRYPTRPEQPVLRGLDLTVKPGQYVALVGPSGCGKSTTIALLERFYDAIAGSILVDGKD 1168
Query: 403 GKKISRKSLRKRIGYVPQETYLFPGTIMENILMA--NPEAKEEDVIRVCKELGIHDFIMK 460
K++ S R + V QE L+ GTI ENIL+ + EE +I+ CK+ I+DFIM
Sbjct: 1169 ISKLNINSYRSFLSLVSQEPTLYQGTIKENILLGIVEDDVPEEFLIKACKDANIYDFIMS 1228
Query: 461 LPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIK 520
LP+G+ T G G +LS G++Q +++ARA+L+DP I++LDEA S++D ++E++VQ A+
Sbjct: 1229 LPEGFNTVVGSKGGMLSGGQKQRVAIARALLRDPKILLLDEATSALDSESEKVVQAALDA 1288
Query: 521 LMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
GRT+I +AHRLS + AD + V D G+IVE G+ EL+ +KG +Y+L Q
Sbjct: 1289 AARGRTTIAVAHRLSTIQKADVIYVFDQGKIVESGTHSELVQKKGRYYELVNLQ 1342
Score = 248 bits (626), Expect = 1e-64
Identities = 166/517 (32%), Positives = 275/517 (53%), Gaps = 27/517 (5%)
Query: 77 FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVL 136
+ +T+ YT G+ + +R E IL+ N+ +F G++ +RI DTN++ D
Sbjct: 181 YVSTVGFIYT---GEHATQKIREYYLESILRQNIGYFDKLGAGEVTTRITADTNLIQD-- 235
Query: 137 VSGLLGGLG-SILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQ 195
G+ +G ++ +LA + A ++ VK + L +V + L GG + + +++
Sbjct: 236 --GISEKVGLTLTALATFVTAFIIAYVKYWKLALICSSTIVALVLTMGGGSQFIIKYSKK 293
Query: 196 KIAKISS---VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ + V EE ++ I AFG + + K++ E K + I MG M
Sbjct: 294 SLDSYGAGGTVAEEVISSIRNATAFGTQDKLAKQYEVHLDEAEKWGTKNQIVMGFMIGAM 353
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ + G GAV +G ++ + + NV + +A+AA
Sbjct: 354 FGLMYSNYGLGFWMGSRFLVDGAVDVGDILTVLMAILIGSFSLGNVSPNAQAFTNAVAAA 413
Query: 313 ERIYEILDDENVED---YEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPAS 366
+I+ +D ++ D EG +++ +G IE RNV Y RP V++DV+L +P
Sbjct: 414 AKIFGTIDRQSPLDPYSNEGKTLDHFEGHIELRNVKHIYPS-RPEVTVMEDVSLSMPAGK 472
Query: 367 KVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFP 426
A+VG +G+GK+T+ L+ RFY P +G +L DG D K ++ + LR++I V QE LF
Sbjct: 473 TTALVGPSGSGKSTVVGLVERFYMPVRGTVLLDGHDIKDLNLRWLRQQISLVSQEPVLFG 532
Query: 427 GTIMENI----LMANPEAKEEDVIR-----VCKELGIHDFIMKLPKGYETSAGEAGKLLS 477
TI +NI + E + ED +R K HDFI LP+GYET+ G+ G LLS
Sbjct: 533 TTIYKNIRHGLIGTKYENESEDKVRELIENAAKMANAHDFITALPEGYETNVGQRGFLLS 592
Query: 478 VGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSIT 537
G++Q I++ARA++ DP I++LDEA S++D K+E +VQ A+ + EGRT+I+IAHRLS
Sbjct: 593 GGQKQRIAIARAVVSDPKILLLDEATSALDTKSEGVVQAALERAAEGRTTIVIAHRLSTI 652
Query: 538 RFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+ A ++V+ +G+I E+G+ EL+ R G + KL +Q
Sbjct: 653 KTAHNIVVLVNGKIAEQGTHDELVDRGGAYRKLVEAQ 689
>gi|9955968 ATP-binding cassette, sub-family B, member 9, isoform 2 [Homo
sapiens]
Length = 723
Score = 254 bits (642), Expect = 2e-66
Identities = 160/579 (27%), Positives = 295/579 (50%), Gaps = 52/579 (8%)
Query: 3 DKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELG 62
+++S + L++ + + L ++ +AL PY AID +I +
Sbjct: 167 EQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFS 226
Query: 63 FIAMLYLLSLVAQWFFTTLQT-FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDL 121
++ L + F ++ +T +F + +R LR+ L ++ FF TGDL
Sbjct: 227 TAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIR-LRNCLFRSLVSQETSFFDENRTGDL 285
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALY 181
+SR+ +DT +V+D++ + L + + + G++V M L +L+LVT P++++++
Sbjct: 286 ISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNI 345
Query: 182 FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR- 240
+G +R +E + +A+ S+ EE+++ ++T+R+F E++ + + + + K +
Sbjct: 346 YGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKE 405
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
A YM W G+ S+G S
Sbjct: 406 AAAYMYYVW------------------------GSGSVG--------------------S 421
Query: 301 MYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRP---VLK 356
+Y L + A E+++E +D + ++G ++ + L+G ++F NV F Y + RP VL+
Sbjct: 422 VYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTY-RTRPHTQVLQ 480
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
+V+ + P A+VG +G+GK++ N++ FY G +L DG K L + I
Sbjct: 481 NVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVIS 540
Query: 417 YVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLL 476
V QE LF +I +NI P E V+ ++ H FIM+L GY T GE G L
Sbjct: 541 LVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQL 600
Query: 477 SVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSI 536
S G++Q +++ARA++++P ++ILDEA S++D ++E L+Q A+ ++ T +IIAHRLS
Sbjct: 601 SGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLST 660
Query: 537 TRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
A ++V+D GR+V++G+ +LL++ G + KL QM
Sbjct: 661 VEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQM 699
>pir||A40366 hemolysin secretion protein appB - Actinobacillus pleuropneumoniae
>gi|141821|gb|AAB00966.1| (M65808) hemolysin determinant
[Actinobacillus pleuropneumoniae]
Length = 707
Score = 253 bits (640), Expect = 3e-66
Identities = 165/566 (29%), Positives = 285/566 (50%), Gaps = 5/566 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R+ ++ + + L +P +V +D ++ + L I + + +
Sbjct: 143 FIPAVIKYRKIFIETLIVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNVITVALAIVV 202
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + L+T+ ++ L ++L +L + +F+ + GD V+R+ +
Sbjct: 203 LFEIVLNGLRTYIFAHSTSRIDVELGARLFRHLLALPISYFENRRVGDTVARVRELDQIR 262
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L + S V M KLTLV L S+P + +++ +RR E
Sbjct: 263 NFLTGQALTSVLDLMFSFIFFAV-MWYYSPKLTLVILGSLPFYMGWSIFISPILRRRLDE 321
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ESV I TI+A + + K + A RV I +
Sbjct: 322 KFARGAHNQSFLVESVTAINTIKALAVTPQMTNTWDKQLASYVSAGFRVTTLATIGQQGV 381
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ +++ + G +L G +SIG ++AF + + P+ + ++ Q ++
Sbjct: 382 QFIQKVVMVITLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISV 441
Query: 313 ERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEKGRPV-LKDVNLYIPPASKVAI 370
R+ ++L+ E Y+G +++ ++KG+I FRN+ F Y+ PV L DVNL I + I
Sbjct: 442 TRLGDVLNSPT-ESYQGKLALPEIKGDITFRNIRFRYKPDAPVILNDVNLSIQQGEVIGI 500
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG++G+GK+T+ LI FY P G++L DG D LR+++G V Q+ L +I
Sbjct: 501 VGRSGSGKSTLTKLIQVFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLGRSIR 560
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
+NI +A+P E ++ K G H+FI +L +GY T GE G LS G+ I++ARA+
Sbjct: 561 DNIALADPGMPMEKIVHAAKLAGAHEFISELREGYNTIVGEQGAGLSGGQPNRIAIARAL 620
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+ +P I+I DEA S++D ++E ++ M ++ +GRT IIIAHRLS + A +IV++ G+
Sbjct: 621 VNNPKILIFDEATSALDYESEHIIMRNMHQICKGRTVIIIAHRLSTVKNAASIIVMEKGQ 680
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQ 576
IVE+G ELL Y Y Q+Q
Sbjct: 681 IVEQGKHKELLRDPNGLYH-YLHQLQ 705
>emb|CAB69672.1| (AL137165) probable ABC transporter protein, ATP-binding component.
[Streptomyces coelicolor A3(2)]
Length = 589
Score = 253 bits (640), Expect = 3e-66
Identities = 168/570 (29%), Positives = 286/570 (49%), Gaps = 22/570 (3%)
Query: 19 SERRTLA--IVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQW 76
++RR LA + V ++ S + L P + +D + G +L L + LV +
Sbjct: 28 ADRRRLAGAVAVFTVKHSPIWLL--PLVTAAIVDTVVQHGPITDLWTSTGLIMFILVVNY 85
Query: 77 FFTTLQTFYTEVFGQKVLRN---LRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVN 133
L Y + V R LRS L ++ Q ++ + S G L ++++ D V
Sbjct: 86 ---PLHLLYVRLLYGSVRRMGTALRSALCTRMQQLSIGYHSRVSAGVLQAKVVRDVETVE 142
Query: 134 DVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRET 193
++ GLG+ L G +V + + + V L VP ++ ++R
Sbjct: 143 QMVQQTAETGLGAFTVLTGGLVIIGVRTPEFLPVFLVVVPAASLLVARLRARLRTHNERF 202
Query: 194 RQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIF----W 249
R ++ +SS V E I RA G E + + + +R+ + G F W
Sbjct: 203 RHEVETLSSRVTEMTRLIPVTRAHGLEGKALRRMDGTLDRLLTSGMRLDLVNGRFGSLSW 262
Query: 250 PLMNIASLLSVIVVIAYGGYLAYKGA--VSIGVVVAFIQYAQRFRGPINNVVSMYDSLQS 307
++N+ +VV+A ++Y V+ G VV + + + +
Sbjct: 263 VVLNVVG----VVVLAGAALISYYDVWGVTAGDVVMLSAFLTTLTNSTTTLAGLAPVITK 318
Query: 308 ALAALERIYEILDDENVEDYEGIS-VEKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPA 365
L ++ + E+L +ED EG + L+G + F V Y+ GRP + D L + P
Sbjct: 319 GLESVRSVGEVLQAPELEDNEGKKELTALRGAVAFEGVGHLYDSDGRPAVSDFTLSVEPG 378
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
+A+VG +GAGK+T+ NL++ F PT G +L DG D + ++ R+ + VPQE+ LF
Sbjct: 379 ETIALVGASGAGKSTVLNLVIGFLRPTSGRLLLDGHDMNTLDLRTYRRFVSVVPQESILF 438
Query: 426 PGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLIS 485
GTI EN+ EA EE V ++ +F+ +LP+G +T GE G LS G+RQ ++
Sbjct: 439 DGTIRENVAYGMDEADEETVRGALRDANALEFVDRLPRGLDTLVGEHGARLSGGQRQRLA 498
Query: 486 LARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIV 545
+ARA+++DP +++LDEA S++D ++E LVQ A+ +L+ GRT+ ++AHRLS R AD+++V
Sbjct: 499 IARALIRDPRVLVLDEATSALDTRSEALVQQALARLLRGRTTFVVAHRLSTVRGADRIVV 558
Query: 546 VDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
+ +GRI E G+ ELL+ G + L++ Q+
Sbjct: 559 MGEGRIQEIGTHEELLAGGGAYAALHSGQV 588
>pir||D82146 transport ATP-binding protein MsbA VC1878 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9656409|gb|AAF95026.1| (AE004263) transport
ATP-binding protein MsbA [Vibrio cholerae]
Length = 582
Score = 253 bits (639), Expect = 4e-66
Identities = 155/578 (26%), Positives = 288/578 (49%), Gaps = 2/578 (0%)
Query: 2 ADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKEL 61
+D+S+ KR + L + +++V +A A+ +L+ +D L
Sbjct: 5 SDESNWQTFKRLWTYIRLYKAGLVVSTIALVINAAADTYMISLLKPLLDEGFGNAESNFL 64
Query: 62 GFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDL 121
+ + L + + ++ V+ +R +L + + FF +STG L
Sbjct: 65 RILPFMILGLMFVRGLSGFASSYCLSWVSGNVVMQMRRRLFNHFMHMPVRFFDQESTGGL 124
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALY 181
+SRI D+ V L+ + S+ G++ M +L+LV + P++ +
Sbjct: 125 LSRITYDSEQVAGATSRALVSIVREGASIIGLLTLMFWNSWQLSLVLIVVAPVVAFAISF 184
Query: 182 FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRV 241
+ R+ R + + ++S E+ + G + + ++G ++ K F KVS + +++
Sbjct: 185 VSKRFRKISRNMQTAMGHVTSSAEQMLKGHKVVLSYGGQEVERKRFDKVSNSMRQQTMKL 244
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
I P++ + + L++ V+ + + ++ G P+ + S+
Sbjct: 245 VSAQSIADPVIQMIASLALFAVLFLASVDSIRAELTPGTFTVVFSAMFGLMRPLKALTSV 304
Query: 302 YDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYE-KGRPVLKDVNL 360
Q +AA + ++ ++D E D E++ GE++ ++V F Y+ K +P L V+
Sbjct: 305 TSEFQRGMAACQTLFGLMDLETERDNGKYEAERVNGEVDVKDVTFTYQGKEKPALSHVSF 364
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
IP VA+VG++G+GK+TIANL RFYD G I DG D + +LR+ V Q
Sbjct: 365 SIPQGKTVALVGRSGSGKSTIANLFTRFYDVDSGSICLDGHDVRDYKLTNLRRHFALVSQ 424
Query: 421 ETYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
+LF TI NI A E E + + ++ +FI +P+G +T GE G LS G
Sbjct: 425 NVHLFNDTIANNIAYAAEGEYTREQIEQAARQAHAMEFIENMPQGLDTVIGENGTSLSGG 484
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
+RQ +++ARA+L+D ++ILDEA S++D ++E+ +Q A+ +L + +T ++IAHRLS
Sbjct: 485 QRQRVAIARALLRDAPVLILDEATSALDTESERAIQAALDELQKNKTVLVIAHRLSTIEQ 544
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
AD+++VVD+G I+E G +LL++ G + +L+ Q E
Sbjct: 545 ADEILVVDEGEIIERGRHADLLAQDGAYAQLHRIQFGE 582
>gb|AAG25076.1|AF273216_1 (AF273216) ABC transporter RzcB [Rhizobium leguminosarum bv.
viciae]
Length = 735
Score = 253 bits (639), Expect = 4e-66
Identities = 166/555 (29%), Positives = 282/555 (49%), Gaps = 12/555 (2%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFI----AMLYLLSLVAQW 76
RR V+++ + + L +P +V +D + Y L + A + L +V Q+
Sbjct: 173 RRAFGHVLIASLVIQIFALVTPLFFQVVVDKVLAHRSYSTLIVLVVGLAAVGLFDVVLQY 232
Query: 77 FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVL 136
L+T+ ++ L +L +L L +F+T++TG V+RI + N +
Sbjct: 233 ----LRTYALSHTTNRIDVELGRRLFRHLLNLPLSYFETRATGQTVARIRELETIRNFLT 288
Query: 137 VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
GL GL I ++ I V + KL + + S+P + I ++ E ++
Sbjct: 289 GQGLFSGLDLIFTIIFIFV-LFSYSSKLAWIVVASIPFYMAIGFLIRPFLKERIDEKFER 347
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
A ++ E+V GI+T++A E V ++ + +++ + + +
Sbjct: 348 GAFSQQLLVETVVGIQTLKASAVEPVVSSQWEERLAAYVRSSFLATMLAAKGQNAIQYVN 407
Query: 257 LLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
++ ++ +G G +S+G +VAF A + PI + ++ Q ++ R+
Sbjct: 408 KITSAALLLFGAQAVIDGELSVGALVAFNMIAGQVSQPILRLSQLWQDFQQVQVSIARLS 467
Query: 317 EILD-DENVEDYEGISVEKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKVAIVGKT 374
+IL+ + +S+ KG I F++V F Y G+ VLKD+N I P + IVG +
Sbjct: 468 DILNAPQEPRPSVAVSLPPPKGAIAFKSVNFRYSPDGQDVLKDINFSIRPGEVIGIVGPS 527
Query: 375 GAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYL-FPGTIMENI 433
G+GK+T+ L+ RFY P G++ DG D ++ LR IG V QE L F TI +NI
Sbjct: 528 GSGKSTLTKLVQRFYIPNNGQVFVDGQDIAQVDPAWLRSNIGVVLQENMLLFNRTIHDNI 587
Query: 434 LMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKD 493
M NP I++ + G FI KLP+GY+T E G LS G+RQ +++ARA+ +
Sbjct: 588 CMVNPAMSRAAAIQMARLSGADQFIAKLPRGYDTLIEERGANLSGGQRQRLAIARALATN 647
Query: 494 PDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVE 553
P I+ILDEA S++D ++E+++ M +++ GRT IIIAHRL+ R +++I + DGRIVE
Sbjct: 648 PPILILDEATSALDYESERIILGNMREIVRGRTVIIIAHRLATVRHCNRIIGMKDGRIVE 707
Query: 554 EGSPGELLSRKGYFY 568
EG+ LL+R Y
Sbjct: 708 EGTHETLLARPNGLY 722
>sp|P18770|CYAB_BORPE CYCLOLYSIN SECRETION ATP-BINDING PROTEIN CYAB >gi|72493|pir||BVBRCB
cyaB protein - Bordetella pertussis
>gi|39733|emb|CAA32412.1| (X14199) cyaB [Bordetella
pertussis]
Length = 712
Score = 252 bits (638), Expect = 6e-66
Identities = 161/569 (28%), Positives = 297/569 (51%), Gaps = 9/569 (1%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + R + V++ + +L +P +V +D ++ + L I + +L ++
Sbjct: 147 FIPALVKHRHLIGEVLLISLVLQFISLLTPLFFQVVMDKVLVNNAMETLNVITVGFLAAI 206
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + T ++T+ K+ L ++L+ +L+ L +F+ + GD V+R+ + +
Sbjct: 207 LFEALLTGIRTYLFAHTSSKLDVELGARLYAHLLRLPLAYFQARRVGDSVARV-RELEHI 265
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
L + L ++ I M VKLTLV L ++P +++L +RR
Sbjct: 266 RAFLTGNAVTVLLDVVFSVVFIAVMFFYSVKLTLVVLAALPCYFLLSLVLTPVLRRRLHV 325
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A+ + + E+V+GI+T+++ E ++ + + + A L VA +
Sbjct: 326 KFNRGAENQAFLVETVSGIDTVKSLAVEPQWQRNWDRQLAGYVAAGLSVA---NVAMLAN 382
Query: 253 NIASLLSVIVVIAYGGYLAYKGA---VSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSAL 309
+L+S ++ G+ A++G +++G +VAF + P+ + +++ Q
Sbjct: 383 TGVTLISRLLRWESCGW-AHRGGRARMTVGELVAFNMLSGHVTQPVIRLAQLWNDFQQTG 441
Query: 310 AALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKV 368
+++R+ +IL+ + + L+G IE V F Y L++V+L I P V
Sbjct: 442 VSMQRLGDILNCRTEVAGDKAQLPALRGSIELDRVSFRYRPDAADALRNVSLRIAPGEVV 501
Query: 369 AIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGT 428
+VG++G+GK+T+ LI R + +G +L DG D + SLR+++G V QE+ LF +
Sbjct: 502 GVVGRSGSGKSTLTRLIQRMFVADRGRVLIDGHDIGIVDSASLRRQLGVVLQESTLFNRS 561
Query: 429 IMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLAR 488
+ +NI + P A +V+ + G H+FI +LP+GY+T GE G LS G+RQ I +AR
Sbjct: 562 VRDNIALTRPGASMHEVVAAARLAGAHEFICQLPEGYDTMLGENGVGLSGGQRQRIGIAR 621
Query: 489 AMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDD 548
A++ P ++ILDEA S++D ++E ++Q M + +GRT IIIAHRLS R AD+++V++
Sbjct: 622 ALIHRPRVLILDEATSALDYESEHIIQRNMRDICDGRTVIIIAHRLSAVRCADRIVVMEG 681
Query: 549 GRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
G + E GS LL+ G + +L Q E
Sbjct: 682 GEVAECGSHETLLAAGGLYARLQALQAGE 710
>pir||C72275 ABC transporter, ATP-binding protein - Thermotoga maritima (strain
MSB8) >gi|4981820|gb|AAD36339.1|AE001781_10 (AE001781)
ABC transporter, ATP-binding protein [Thermotoga
maritima]
Length = 577
Score = 252 bits (638), Expect = 6e-66
Identities = 143/498 (28%), Positives = 267/498 (52%), Gaps = 5/498 (1%)
Query: 84 FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGG 143
F+ +K +++ K+L FF +G+L++R ND +++ VL G +
Sbjct: 79 FFLGGTARKFFLETSNKMFSKLLSLTPGFFDRMKSGELMARFTNDLSLLRRVLGQGAILF 138
Query: 144 LGSILSLAGIIVAML-LLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISS 202
S + + + M+ + KL+ ++ + L+ +++ FG + R E ++ +++S
Sbjct: 139 FDSFIMIVMVFFFMIGNVGWKLSWISFAPLLLLAPVSMSFGRLIHRKVSEVQRSFSELSG 198
Query: 203 VVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIV 262
EE+++ + +++F E K F + + + L +F PL+N+ + + +
Sbjct: 199 FTEETISSVRIVKSFSVEDVSFKIFENRALKNYEDTLSAIKVSSVFRPLINLIASTAFFL 258
Query: 263 VIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEIL--D 320
+ YGG G +S+G +AF Y P+ M D Q AA+ R+ I
Sbjct: 259 ALLYGGRAVINGKISLGDFIAFNSYLGMLVWPMMAYGFMVDLFQRGRAAMRRLDTIFTAQ 318
Query: 321 DENVEDYEGISVEKLKGEIEFRNVWFEYE-KGRPVLKDVNLYIPPASKVAIVGKTGAGKT 379
E E + I ++ + E RN+ + Y R VLK+V + I + I G G+GK+
Sbjct: 319 PEVKEPEKPIRIDHFES-FEVRNLTYRYPGTEREVLKNVTMKINRGEMIGIAGSVGSGKS 377
Query: 380 TIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPE 439
TIA L+++ Y +G+I +G+D +S +++R + VPQET+LF T+ NI +
Sbjct: 378 TIAKLLVKLYPVERGKIFINGVDINDVSSENIRSIVTLVPQETFLFSDTVRNNITVGLEN 437
Query: 440 AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVIL 499
E+ + V K ++D IM P+ ++T GE G LS G++Q I++ARA+++D ++ I
Sbjct: 438 VDEKKIEEVTKLAAVYDDIMSFPEKFDTIVGERGVTLSGGQKQRITIARALIRDFEVYIF 497
Query: 500 DEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGE 559
D+ LS+VDP+TE+ + +++ K M+G+T ++I HRL + + AD++ V+ +GR++EEG+ E
Sbjct: 498 DDCLSAVDPETEERIIDSIRKGMKGKTIVVITHRLKVLKNADRIYVLHEGRVIEEGTHEE 557
Query: 560 LLSRKGYFYKLYTSQMQE 577
L+ R G + ++Y Q+ E
Sbjct: 558 LMIRDGMYSRMYRKQLIE 575
>pir||T42842 bile salt transport protein, ATP-dependent - rat
>gi|3075422|gb|AAC40084.1| (U69487) bile salt export
pump [Rattus norvegicus]
Length = 1321
Score = 251 bits (635), Expect = 1e-65
Identities = 160/500 (32%), Positives = 257/500 (51%), Gaps = 16/500 (3%)
Query: 88 VFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
+ G + +R +R +I++ + +F S G+L SR +D +ND + L L +
Sbjct: 165 ITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQLAHFLQRM 224
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEES 207
+ ++ KLTLV L PL+ I A G + + + AK S+ +E
Sbjct: 225 STAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKAGSIADEV 284
Query: 208 VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
++ I T+ AFG E + + K + + + MG F M + YG
Sbjct: 285 LSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYG 344
Query: 268 GYLA-----YKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE 322
L Y + + + I A I + S + + +A I++ +D +
Sbjct: 345 STLVLDEEEYTPGTLVQIFLCVILAAMN----IGHASSCLEIFSTGCSAATNIFQTIDRQ 400
Query: 323 NVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGA 376
V D +G ++++KGEIEF NV F Y RP +L ++++ I P A+VG +GA
Sbjct: 401 PVIDCMSGDGYKLDRIKGEIEFHNVTFHYPS-RPDVKILDNLSMVIKPGETTALVGSSGA 459
Query: 377 GKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMA 436
GK+T LI RFYDP +G + DG D + ++ + LR +IG V QE LF TI ENI
Sbjct: 460 GKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFG 519
Query: 437 NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDI 496
+A ED+++ K+ ++FIM LP+ ++T GE G +S G++Q +++ARA++++P I
Sbjct: 520 REDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKI 579
Query: 497 VILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGS 556
++LD A S++D ++E VQ A+ K+ G T I +AHRLS R AD +I + G VE G+
Sbjct: 580 LLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGT 639
Query: 557 PGELLSRKGYFYKLYTSQMQ 576
ELL RKG ++ L T Q Q
Sbjct: 640 HEELLERKGVYFMLVTLQSQ 659
Score = 233 bits (588), Expect = 4e-60
Identities = 157/519 (30%), Positives = 262/519 (50%), Gaps = 17/519 (3%)
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGD 120
F +L +S+ Q+ LQ + G+ + + LR + +L ++ +F + G
Sbjct: 801 FFVILGCVSIFTQF----LQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGV 856
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L +R+ D + V S + + S ++ ++ KL+L+ P + +
Sbjct: 857 LTTRLATDASQVQGATGSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGA 916
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+ + +Q + K + E+++ I T+ G E K F + K +R
Sbjct: 917 VQTKMLTGFASQDKQALEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVR 976
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYL-AYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
A G+ + + L+ YGGYL AY+G + V + +
Sbjct: 977 KANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEG-LGFSHVFRVVSSVALSATAVGRTF 1035
Query: 300 SMYDSLQSALAALERIYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP--- 353
S S A + R +++LD + NV G + +G+I+F + F Y RP
Sbjct: 1036 SYTPSYAKAKISAARFFQLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPS-RPDIQ 1094
Query: 354 VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRK 413
VL +++ + P +A VG +G GK+T L+ RFYDP +G ++ DG D KK++ + LR
Sbjct: 1095 VLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQFLRS 1154
Query: 414 RIGYVPQETYLFPGTIMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
IG V QE LF +IM+NI + E E I K+ +HDF+M LP+ YET+ G
Sbjct: 1155 NIGIVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGI 1214
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G LS GE+Q I++ARA+++DP I++LDEA S++D ++E+ VQ A+ K EGRT I+IA
Sbjct: 1215 QGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTCIVIA 1274
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
HRLS + +D + VV G ++E+G+ +L+++KG +YKL
Sbjct: 1275 HRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKL 1313
>pir||T42228 P-glycoprotein sister - rat >gi|3273484|gb|AAC24753.1| (AF010597)
P-glycoprotein sister [Rattus norvegicus]
Length = 1321
Score = 251 bits (635), Expect = 1e-65
Identities = 160/500 (32%), Positives = 257/500 (51%), Gaps = 16/500 (3%)
Query: 88 VFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
+ G + +R +R +I++ + +F S G+L SR +D +ND + L L +
Sbjct: 165 ITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQLAHFLQRM 224
Query: 148 LSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEES 207
+ ++ KLTLV L PL+ I A G + + + AK S+ +E
Sbjct: 225 STAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKAGSIADEV 284
Query: 208 VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
++ I T+ AFG E + + K + + + MG F M + YG
Sbjct: 285 LSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYG 344
Query: 268 GYLA-----YKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE 322
L Y + + + I A I + S + + +A I++ +D +
Sbjct: 345 STLVLDEEEYTPGTLVQIFLCVILAAMN----IGHASSCLEIFSTGCSAATNIFQTIDRQ 400
Query: 323 NVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGA 376
V D +G ++++KGEIEF NV F Y RP +L ++++ I P A+VG +GA
Sbjct: 401 PVIDCMSGDGYKLDRIKGEIEFHNVTFHYPS-RPDVKILDNLSMVIKPGETTALVGSSGA 459
Query: 377 GKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMA 436
GK+T LI RFYDP +G + DG D + ++ + LR +IG V QE LF TI ENI
Sbjct: 460 GKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFG 519
Query: 437 NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDI 496
+A ED+++ K+ ++FIM LP+ ++T GE G +S G++Q +++ARA++++P I
Sbjct: 520 REDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKI 579
Query: 497 VILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGS 556
++LD A S++D ++E VQ A+ K+ G T I +AHRLS R AD +I + G VE G+
Sbjct: 580 LLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGT 639
Query: 557 PGELLSRKGYFYKLYTSQMQ 576
ELL RKG ++ L T Q Q
Sbjct: 640 HEELLERKGVYFMLVTLQSQ 659
Score = 233 bits (587), Expect = 6e-60
Identities = 157/519 (30%), Positives = 262/519 (50%), Gaps = 17/519 (3%)
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGD 120
F +L +S+ Q+ LQ + G+ + + LR + +L ++ +F + G
Sbjct: 801 FFVILGCVSIFTQF----LQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGV 856
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
L +R+ D + V S + + S ++ ++ KL+L+ P + +
Sbjct: 857 LTTRLATDASQVQGATGSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGA 916
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
+ + +Q + K + E+++ I T+ G E K F + K +R
Sbjct: 917 VQTKMLTGFASQDKQALEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVR 976
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYL-AYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
A G+ + + L+ YGGYL AY+G + V + +
Sbjct: 977 KANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEG-LGFSHVFRVVSSVVLSATAVGRTF 1035
Query: 300 SMYDSLQSALAALERIYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP--- 353
S S A + R +++LD + NV G + +G+I+F + F Y RP
Sbjct: 1036 SYTPSYAKAKISAARFFQLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPS-RPDIQ 1094
Query: 354 VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRK 413
VL +++ + P +A VG +G GK+T L+ RFYDP +G ++ DG D KK++ + LR
Sbjct: 1095 VLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQFLRS 1154
Query: 414 RIGYVPQETYLFPGTIMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
IG V QE LF +IM+NI + E E I K+ +HDF+M LP+ YET+ G
Sbjct: 1155 NIGIVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGI 1214
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G LS GE+Q I++ARA+++DP I++LDEA S++D ++E+ VQ A+ K EGRT I+IA
Sbjct: 1215 QGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTCIVIA 1274
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
HRLS + +D + VV G ++E+G+ +L+++KG +YKL
Sbjct: 1275 HRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKL 1313
>pir||B71676 probable ABC transporter msbA2 - Rickettsia prowazekii
>gi|3861232|emb|CAA15132.1| (AJ235272) PROBABLE
TRANSPORT ATP-BINDING PROTEIN MSBA (msbA2) [Rickettsia
prowazekii]
Length = 576
Score = 251 bits (635), Expect = 1e-65
Identities = 164/578 (28%), Positives = 298/578 (51%), Gaps = 15/578 (2%)
Query: 7 LSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY----KELG 62
+ LL R K ++ L IV++S++ + + L I R ID + K +
Sbjct: 3 IKLLYRLAKYLRFYKKDLIIVMISLLSVSASLLLIGSIFRDLIDRGLAEDNILSVNKSIL 62
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
+I +L ++ VA +F ++++ +K++ +R + + ++ ++ ++ GD++
Sbjct: 63 YICLLIVILSVASFF----RSYFINNVAEKIVNQIRKEAYSNLINYEIEEYEELKIGDII 118
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
SR+ ND + + ++V+ L + + + L G I M KL + + ++P++++ + F
Sbjct: 119 SRLTNDIDQIATLIVNFLSFFIRNSVMLIGSITLMFFESFKLASIVIITIPILLVPLIKF 178
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEF-SKVSTETIKAYLRV 241
G ++ ++ + + + S ++E+ I I AF + + +F +K+ + I R+
Sbjct: 179 GKHVKALSKKALESKSLLVSDIDETFNNIRVIYAFNHQINKIADFDTKLQSYLIYCKTRL 238
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
I +F+ + L++ +++ G +G +S G +++FI YA + +
Sbjct: 239 KI-RALFFAISIAVIFLTITLIVWIGASDIVQGDLSAGQIISFIYYAIIAGVSSGGIFEL 297
Query: 302 YDSLQSALAALERIYEILDDENVEDYEGISVEKLKG-EIEFRNVWFEYEKGRPVLKDVN- 359
+ ALERI I+D ++ ++ IEF+NV F Y RP LK +N
Sbjct: 298 LSEMHLPTTALERIITIIDKTSIVHNNYYALNNSDAISIEFKNVDFTYNS-RPNLKVINN 356
Query: 360 --LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
L I V IVG++GAGK+T+ L++RFY G IL + D + +RK I Y
Sbjct: 357 MSLKINSNKFVGIVGRSGAGKSTLIQLLLRFYRQENGTILINNQDISFVKPTDIRKFIAY 416
Query: 418 VPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLS 477
VPQE +F TI NI+ N +A + ++ + K GI +F KL G T GE G LS
Sbjct: 417 VPQEASIFSDTIKSNIIFGNNKASDYEINEIIKITGIEEFSTKLHDGINTKIGEKGVRLS 476
Query: 478 VGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSIT 537
G++Q I++ARA+L+ P I++LDEA+S++D +EQ + NA+ K+M+G I IAHR+S
Sbjct: 477 GGQKQRIAIARALLRKPKILLLDEAMSALDTMSEQKLLNAIKKIMKGNIIISIAHRISSI 536
Query: 538 RFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQM 575
AD ++V+D G +V EGS +L + + Q+
Sbjct: 537 ESADYILVIDKGGVVTEGSHYDLSKNSEIYRNICREQL 574
>sp|P77265|MDLA_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLA
>gi|7445960|pir||H64774 ABC-type transport protein mdlA
- Escherichia coli >gi|1773132|gb|AAB40204.1| (U82664)
multidrug resistance-like ATP-binding protein Mdl
[Escherichia coli] >gi|1786653|gb|AAC73551.1| (AE000151)
ATP-binding component of a transport system [Escherichia
coli K12]
Length = 590
Score = 250 bits (632), Expect = 3e-65
Identities = 161/562 (28%), Positives = 299/562 (52%), Gaps = 8/562 (1%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAM-LYLLSLVAQWFFT 79
RR L V + ++ A+ L P ++ + +D + ++ G I M + + L+A +
Sbjct: 16 RRYLGAVALLVI-IAMLQLVPPKVVGIVVDG--VTEQHFTTGQILMWIATMVLIAVVVYL 72
Query: 80 TLQTFYTEVFGQ--KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLV 137
+ +FG ++ LR + ++ + + +F+ TGDL++R ND + V
Sbjct: 73 LRYVWRVLLFGASYQLAVELREDYYRQLSRQHPEFYLRHRTGDLMARATNDVDRVVFAAG 132
Query: 138 SGLLGGLGSILSLAGIIVAMLL-LDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
G+L + S++ +++ M + +LTL +L +P+M I+ G + ++ +
Sbjct: 133 EGVLTLVDSLVMGCAVLIMMSTQISWQLTLFSLLPMPVMAIMIKRNGDALHERFKLAQAA 192
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
+ ++ +ES+ I I+AFG E F+ + +T K +RVA F P + IA
Sbjct: 193 FSSLNDRTQESLTSIRMIKAFGLEDRQSALFAADAEDTGKKNMRVARIDARFDPTIYIAI 252
Query: 257 LLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
++ ++ I G ++ +G++++G + +F+ Y P+ + M++ ++ AA RI
Sbjct: 253 GMANLLAIGGGSWMVVQGSLTLGQLTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIR 312
Query: 317 EILDDENVEDYEGISVEKLKGEIEFRNVWFEY-EKGRPVLKDVNLYIPPASKVAIVGKTG 375
+L + V + V + +GE++ F Y + P L++VN + P + I G TG
Sbjct: 313 AMLAEAPVVNDGSEPVPEGRGELDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTG 372
Query: 376 AGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILM 435
+GK+T+ +LI R +D ++G+I + I K+ S R R+ V Q +LF T+ NI +
Sbjct: 373 SGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIAL 432
Query: 436 ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPD 495
P A ++++ V + +HD I++LP+GY+T GE G +LS G++Q IS+ARA+L + +
Sbjct: 433 GCPNATQQEIEHVARLASVHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAE 492
Query: 496 IVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEG 555
I+ILD+ALS+VD +TE + + + + +GRT II AHRLS A ++IV+ G I + G
Sbjct: 493 ILILDDALSAVDGRTEHQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRG 552
Query: 556 SPGELLSRKGYFYKLYTSQMQE 577
+ L + G++ +Y Q E
Sbjct: 553 NHDVLAQQSGWYRDMYRYQQLE 574
>gb|AAF17668.1|AC009398_17 (AC009398) F20B24.12 [Arabidopsis thaliana]
Length = 1316
Score = 250 bits (632), Expect = 3e-65
Identities = 173/560 (30%), Positives = 287/560 (50%), Gaps = 53/560 (9%)
Query: 60 ELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF-KTKST 118
E+ I++L+ V T++ + G+++ +R ++ IL++ + +F K +T
Sbjct: 764 EVKRISILFCCGSVITVIVHTIEHTTFGIMGERLTLRVRQKMFSAILRNEIGWFDKVDNT 823
Query: 119 GD-LVSRIINDTNVVNDVLVSG---LLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPL 174
L SR+ +D ++ ++V LL LG +++ + +L+ +LTLV L + PL
Sbjct: 824 SSMLASRLESDATLLRTIVVDRSTILLENLGLVVTA---FIISFILNWRLTLVVLATYPL 880
Query: 175 MV-----------------------IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGI 211
++ I +GG + +AY K + + ES++ I
Sbjct: 881 IISGHISEVKRSFLRFYILFFGRQKIFMQGYGGNLSKAY-------LKANMLAGESISNI 933
Query: 212 ETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVI------- 264
T+ AF E+ V +SK E + R GI + + S + +
Sbjct: 934 RTVVAFCAEEKVLDLYSKELLEPSERSFRRGQMAGILYGVSQFFIFSSYGLALWYIYKLF 993
Query: 265 --AYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE 322
YG L KG S V+ + V+++ L + ++E+LD
Sbjct: 994 HTKYGSILMEKGLSSFESVMKTFMVLIVTALVMGEVLALAPDLLKGNQMVVSVFELLDRR 1053
Query: 323 N-VEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGK 378
V G + ++G IE + V F Y RP + D NL +P +A+VG++G+GK
Sbjct: 1054 TQVVGDTGEELSNVEGTIELKGVHFSYPS-RPDVTIFSDFNLLVPSGKSMALVGQSGSGK 1112
Query: 379 TTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANP 438
+++ +L++RFYDPT G I+ DG D KK+ KSLR+ IG V QE LF TI ENIL
Sbjct: 1113 SSVLSLVLRFYDPTAGIIMIDGQDIKKLKLKSLRRHIGLVQQEPALFATTIYENILYGKE 1172
Query: 439 EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVI 498
A E +V+ K H FI LP+GY T GE G +S G+RQ I++ARA+LK+P+I++
Sbjct: 1173 GASESEVMEAAKLANAHSFISSLPEGYSTKVGERGIQMSGGQRQRIAIARAVLKNPEILL 1232
Query: 499 LDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPG 558
LDEA S++D ++E++VQ A+ +LM RT++++AHRLS + +D + V+ DG+I+E+GS
Sbjct: 1233 LDEATSALDVESERVVQQALDRLMRDRTTVVVAHRLSTIKNSDMISVIQDGKIIEQGSHN 1292
Query: 559 ELLSRK-GYFYKLYTSQMQE 577
L+ K G + KL + Q ++
Sbjct: 1293 ILVENKNGPYSKLISLQQRQ 1312
Score = 212 bits (534), Expect = 9e-54
Identities = 155/542 (28%), Positives = 257/542 (46%), Gaps = 72/542 (13%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKTK-STGDLVSRIINDTNVVND-------------V 135
G++ +R +L ++ F T+ STG+++S I ++ VV D V
Sbjct: 112 GERQAAKIRKAYLRSMLSQDISLFDTEISTGEVISAITSEILVVQDAISEKVRYTKIKPV 171
Query: 136 LVSG--------------LLGGLGSILS--LAGIIVAMLLLDVKLTLVTLTSVPLMVIIA 179
LV L+G +S +AG + + +++LVTL+ VP + +
Sbjct: 172 LVLNFGCWIFNFPIASMHLVGNFMHFISRFIAGFAIGFASV-WQISLVTLSIVPFIALAG 230
Query: 180 LYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYL 239
+ R+ K + + EE + + T++AF E+ + T
Sbjct: 231 GIYAFVSSGLIVRVRKSYVKANEIAEEVIGNVRTVQAFTGEEKAVSSYQGALRNTYNYGR 290
Query: 240 RVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIG---------VVVAFIQYAQR 290
+ + G+ ++ LS ++I + + +KG + G V+ F A
Sbjct: 291 KAGLAKGLGLGSLHFVLFLSWALLIWFTSIVVHKGIANGGESFTTMLNVVIAGFHNKALF 350
Query: 291 FRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEK 350
+ + A AA I+++++ N ED G + + G+I F++V F Y
Sbjct: 351 LYRSLGQAAPDISTFMRASAAAYPIFQMIE-RNTEDKTGRKLGNVNGDILFKDVTFTYPS 409
Query: 351 GRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKIS 407
RP + +N IP VA+VG +G+GK+T+ +LI RFY+PT G ++ DG D + +
Sbjct: 410 -RPDVVIFDKLNFVIPAGKVVALVGGSGSGKSTMISLIERFYEPTDGAVMLDGNDIRYLD 468
Query: 408 RKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYET 467
K LR IG V QE LF TI ENI+ +A E++ K FI LP+G+ET
Sbjct: 469 LKWLRGHIGLVNQEPVLFATTIRENIMYGKDDATSEEITNAAKLSEAISFINNLPEGFET 528
Query: 468 SA---------------------------GEAGKLLSVGERQLISLARAMLKDPDIVILD 500
GE G LS G++Q IS++RA++K+P I++LD
Sbjct: 529 QVCRTSDSLEHKKLTTVNPRFCLLFGLQVGERGIQLSGGQKQRISISRAIVKNPSILLLD 588
Query: 501 EALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGEL 560
EA S++D ++E++VQ A+ ++M GRT++++AHRLS R AD + VV G+I+E GS EL
Sbjct: 589 EATSALDAESEKIVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVGGGKIIESGSHDEL 648
Query: 561 LS 562
+S
Sbjct: 649 IS 650
>pir||S30327 multidrug resistance protein 1 - Entamoeba histolytica
>gi|158971|gb|AAA29112.1| (M88599) P-glycoprotein-1
[Entamoeba histolytica]
Length = 1302
Score = 249 bits (630), Expect = 5e-65
Identities = 166/513 (32%), Positives = 267/513 (51%), Gaps = 20/513 (3%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
LQT V + +RS + +L+ + +F TG+L S+IIND + D G+
Sbjct: 130 LQTICFFVLSEYQGIKIRSLYFKALLRQDPGWFDCHKTGELTSKIINDIQKIQD----GM 185
Query: 141 LGGLGSIL-SLAGIIVAMLLLDVK---LTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
G + + + I L+ +K LTLV L P +++ + G ++ +
Sbjct: 186 SLKFGRLFQTFSSFITGYLIGFIKCWDLTLVVLCMFPFIMVSMMGLGMSAGIFTMKSHKP 245
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
++ S+ E+++ I T+ + +E+ + ++ ET K ++ +I +G M
Sbjct: 246 FSEACSIAEQTIGNIRTVHSLTQERSFCESYNTKIMETDKYNIKKSIGIGTGLGCMMFFI 305
Query: 257 LLSVIVVIAYGGYLAY-KGA---VSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ S + YG ++ KG V G V+ ++ + + + L SA A
Sbjct: 306 MSSNALGSWYGNFVVRGKGGSDNVKAGTVLTVFMSVLLATQSLSQISTPINILNSAKVAA 365
Query: 313 ERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEYEK--GRPVLKDVNLYIPPASK 367
+Y+ +D D + + G + G I F +V F Y VLK ++L I
Sbjct: 366 FNVYQTIDRIPDIDCQSIGGECPTECNGNIRFEDVQFVYPTRLSHHVLKGLDLEIKKGQT 425
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
+A+VG +G GK+T LI R YDP G + DG D ++++ K LR +IG V QE LF G
Sbjct: 426 IALVGASGCGKSTTIQLIQRNYDPNGGRVTLDGKDIRELNIKWLRNQIGLVGQEPVLFAG 485
Query: 428 TIMENILMANPEA---KEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLI 484
TI ENI++ E EE++I K HDFI KLP+GY+T GE G LLS G++Q I
Sbjct: 486 TIRENIMLGAKEGATPSEEEMIECAKMANAHDFISKLPEGYDTIIGEKGALLSGGQKQRI 545
Query: 485 SLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVI 544
++ARA++++P I++LDEA S++D ++E++VQ A+ K +GRT+II+AHRL+ R ADK+
Sbjct: 546 AIARALIRNPSILLLDEATSALDTQSEKIVQEALEKASKGRTTIIVAHRLTTVRNADKIC 605
Query: 545 VVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
V G I+E+G EL+ KG +Y L Q E
Sbjct: 606 VFHQGEIIEQGKHQELMDLKGTYYGLVKRQSME 638
Score = 233 bits (589), Expect = 3e-60
Identities = 158/524 (30%), Positives = 262/524 (49%), Gaps = 46/524 (8%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKTKST--GDLVSRIINDTNVVNDVLVSGLLGGLGSI 147
G+K++ +R + + I+ N+ +F + G + +++ +D + + + G + I
Sbjct: 789 GEKMIGRIRRRFYYSIMHQNVSWFDRRENMVGAVTTKLTSDPTSLQGISAERV-GDIIEI 847
Query: 148 LSLAGIIVAM-LLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEE 206
+S G + L KL+L L P++ G + + + + E
Sbjct: 848 MSTVGFGFGIGLYFSWKLSLCILAVFPIISFFMFINGQLNSKNAAPAKAAYEQCGVTLVE 907
Query: 207 SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAY 266
V ++T ++ GKE FS+ ++ R I G + N + L + AY
Sbjct: 908 VVEAMKTAQSLGKED----YFSQKYNNDLQIPKRGIIKWGPLLSITNAITNLLTFSINAY 963
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSAL----------------- 309
G YL I + I Y Q ++ ++ + +Q AL
Sbjct: 964 GYYLG------ICFMKKTINYQQDVPNFVDEIIDTFGDIQKALMTINSATTSFAQIGNVL 1017
Query: 310 -------AALERIYEILDDE-NVEDY--EGISVEKLKGEIEFRNVWFEY--EKGRPVLKD 357
A + IY I+D + +++ Y EG + +KGEIEF+N+ F Y VLK
Sbjct: 1018 PDVGKAVGAAKSIYNIIDRKPSIDCYSEEGETFNDVKGEIEFKNIHFRYPTRADNEVLKG 1077
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
++ +A+VG +G GK+T LI RFYDPT GE+L DG + K ++ LR +IG
Sbjct: 1078 ISFKAEQGKTIALVGASGCGKSTTIQLIERFYDPTSGEVLLDGHNIKDLNIHFLRNQIGL 1137
Query: 418 VPQETYLFPGTIMENILMANPEAKE---EDVIRVCKELGIHDFIMKLPKGYETSAGEAGK 474
V QE LF ++++NI PE E E + K HDFI +P+GY T G+ G
Sbjct: 1138 VGQEPVLFAESVIDNIKRGVPEGVEVSNEQIYAAAKMANAHDFISAMPEGYNTMVGDRGS 1197
Query: 475 LLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRL 534
LS G++Q I++ARA++++P +++LDEA S++D ++E++VQ+A+ K +GRT+I+IAHRL
Sbjct: 1198 QLSGGQKQRIAIARALIRNPKVLLLDEATSALDSESEKIVQDALDKASKGRTTIVIAHRL 1257
Query: 535 SITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
S + ADK+ V+ G+IVE+G EL+ KG++Y L Q V
Sbjct: 1258 STIQNADKIYVIMRGKIVEQGKHQELIDLKGFYYTLAMQQFGTV 1301
>sp|P57551|MDLA_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLA
>gi|10039142|dbj|BAB13176.1| (AP001119) multidrug
resistance-like ATP-binding protein mdl [Buchnera sp.
APS]
Length = 589
Score = 249 bits (629), Expect = 7e-65
Identities = 165/570 (28%), Positives = 300/570 (51%), Gaps = 21/570 (3%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTT 80
+R L +++ I+ + L L P I+ V ID II + + + ++ LVA +
Sbjct: 16 KRYLGAILLLIIIATL-QLLPPKIVGVLID-LIIKKNMHGVQILPWILIIFLVAVIVYIL 73
Query: 81 LQTFYTEVFGQ--KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVS 138
+ +FG ++ LR + + + Q + FF TGDL++R ND + V
Sbjct: 74 RYLWRILLFGASYQLATELRVKFYTYLSQQSQIFFLKNRTGDLIARATNDVDRVVFAAGE 133
Query: 139 GLLGGLGS-ILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKI 197
G+L + S ++ + +IV + LT+++L +P+M I+ +G ++ +R +
Sbjct: 134 GVLTLVDSLVMGFSVLIVMSTQISFLLTIISLIPMPIMAILIKKYGKELHETFRHAQISF 193
Query: 198 AKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASL 257
+ +++ +E + I IRAFG EK+ +F+ ++ T K + VA F P++ ++
Sbjct: 194 SLLNNQTQEILTSIRMIRAFGLEKNQSNKFNIITRNTGKKNMEVAKIDARFDPVIYLSVA 253
Query: 258 LSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYE 317
S ++ I GG+L + +SIG + +FI Y P+ + M++ ++ AA +RI+
Sbjct: 254 FSNLLAIIGGGWLVWNNQISIGQLTSFIMYLGLMIWPMLALAWMFNIVERGSAAWDRIHS 313
Query: 318 ILDDE--------NVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVA 369
I++ + N+ Y GI I + ++ + +P LKD+ + I P + +
Sbjct: 314 IINKKLYIEDGKNNIPPYPGIL------NINIKKFYYPNNQ-KPSLKDIRILIKPGNTLG 366
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
I G TG+GK+T+ LI R ++ K EI Y + +I R+RI V Q ++LF TI
Sbjct: 367 ICGPTGSGKSTLLMLIQRQFNFKKEEIHYHSLSLLEIKIDDWRRRIAVVNQTSFLFSDTI 426
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
NI + P A ++++ V K +H I+ LP+ YET GE G +LS G++Q + +ARA
Sbjct: 427 SNNISLGKPNASQKEIEEVAKLADVHKDIIDLPERYETQVGERGVMLSGGQKQRVCIARA 486
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII-AHRLSITRFADKVIVVDD 548
+L + +I+ILD+ALS+VD +TE + + + + + S+II HRLS +D++IV+
Sbjct: 487 LLLNAEILILDDALSAVDAQTENNILKNINEWKKKKHSLIITTHRLSALINSDEIIVIKS 546
Query: 549 GRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
G I++ G+ +L+ K ++ +Y Q E+
Sbjct: 547 GSIIQRGNHLKLIQEKNWYKSMYYYQQSEI 576
>gb|AAB51079.1| (L40491) leucocin A translocator [Leuconostoc gelidum]
Length = 717
Score = 249 bits (628), Expect = 9e-65
Identities = 155/568 (27%), Positives = 296/568 (51%), Gaps = 12/568 (2%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L FI ++ + +V++ + L ++ Y L+ ID YI LG +++ +
Sbjct: 154 LTSFIPVITRQKLLVINIVIAALLVTLVSILGSYYLQGIIDTYIPDNMKNTLGIVSLGLI 213
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
+ V Q + + + V GQ++ ++ + I + + FF T+ TG++VSR D
Sbjct: 214 FAYVIQQLLSYARDYLLIVMGQRLSIDIILSYIKHIFELPMSFFATRRTGEIVSRF-TDA 272
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
N + + L S +L + L + +++ + L L++L ++P ++ F +
Sbjct: 273 NAIIEALASTMLSVFLDLGILVIVGTVLVVQNSTLFLISLIAIPAYALVVWLFMRPFSKM 332
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
+ Q + +SS + E + G+ETI+A E E + K+ E + + +Y
Sbjct: 333 NNDQMQAGSMLSSSIIEDINGVETIKALNSE---ETAYHKIDHEFVTYLEKSFVYAKTEA 389
Query: 250 PLMNIASLLSV---IVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQ 306
I SLL + +V++ G L +S+G ++ + F P+ N++++ LQ
Sbjct: 390 TQNAIKSLLQLSLNVVILWVGAQLVMTNKISVGQLITYNALLGFFTDPLQNIINLQTKLQ 449
Query: 307 SALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPP 364
A A R+ E+ +D E ++ + ++ ++Y G P + DV+L I
Sbjct: 450 QASVANNRLNEVYLVDSEFKASHQMTESIMPNSSLVADHITYKYGFGAPAIDDVSLTITA 509
Query: 365 ASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYL 424
K+A+VG +G+GK+T+ L++ F+ P G I + + LR I Y+PQE ++
Sbjct: 510 GEKIALVGISGSGKSTLVKLLVNFFQPESGTISLGQTPLANLDKHELRAHINYLPQEPFI 569
Query: 425 FPGTIMENILM-ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQL 483
F G+IM+N+L+ A P +ED+IR + I D I K+ +G+ T E+G +S G++Q
Sbjct: 570 FSGSIMDNLLLGAKPGTTQEDIIRAVEIAEIKDDIEKMSQGFGTELAESGN-ISGGQKQR 628
Query: 484 ISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKV 543
I+LARA+L D ++ILDE+ S++D TE+ + + +++L E +T I +AHRL+I++ D++
Sbjct: 629 IALARAILVDSPVLILDESTSNLDVLTEKKIIDNLMQLTE-KTIIFVAHRLTISQRVDRI 687
Query: 544 IVVDDGRIVEEGSPGELLSRKGYFYKLY 571
+ + +G+I+E+G+ LL+ G++ L+
Sbjct: 688 LTMQNGKIIEDGTHNTLLNAGGFYASLF 715
>sp|Q10418|MESD_LEUME MESENTERICIN Y105 TRANSPORT ATP-BINDING PROTEIN MESD
>gi|1075664|pir||S52205 mesI protein - Leuconostoc
mesenteroides >gi|609084|emb|CAA57402.1| (X81803) mesD
[Leuconostoc mesenteroides]
Length = 722
Score = 248 bits (627), Expect = 1e-64
Identities = 156/568 (27%), Positives = 294/568 (51%), Gaps = 12/568 (2%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
L FI ++ + +V++ + L ++ Y L+ ID YI LG +++ +
Sbjct: 159 LTSFIPVITRQKLLVINIVIAALLVTLVSILGSYYLQGIIDTYIPNNMKNTLGIVSLGLI 218
Query: 70 LSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT 129
+ V Q + + + V GQ++ ++ + I + + FF T+ TG++VSR D
Sbjct: 219 FAYVIQQLLSYARDYLLIVMGQRLSIDIILSYIKHIFELPMSFFATRRTGEIVSRF-TDA 277
Query: 130 NVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
N + + L S +L + L + +++ + L L++L ++P ++ F +
Sbjct: 278 NAIIEALASTMLSVFLDLGILVIVGTVLVVQNSTLFLISLIAIPAYALVVWLFMRPFSKM 337
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW 249
+ Q + +SS + E + G+ETI+A E + K+ E + + +Y
Sbjct: 338 NNDQMQAGSMLSSSIIEDINGVETIKALNSEATA---YHKIDHEFVTYLEKSFVYAKTEA 394
Query: 250 PLMNIASLLSV---IVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQ 306
I SLL + +V++ G L +S+G ++ + F P+ N++++ LQ
Sbjct: 395 VQNAIKSLLQLSLNVVILWVGAQLVMTNKISVGQLITYNALLGFFTDPLQNIINLQTKLQ 454
Query: 307 SALAALERIYEI--LDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPP 364
A A R+ E+ +D E + ++ + ++ ++Y G P + DV+L I
Sbjct: 455 QASVANNRLNEVYLVDSEFKDSHQMTEKITPNSSLVADHITYKYGFGAPAIDDVSLTITA 514
Query: 365 ASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYL 424
K+A+VG +G+GK+T+ L++ F+ P G I + + LR I Y+PQE ++
Sbjct: 515 GEKIALVGISGSGKSTLVKLLVNFFQPESGTISLGPTPLANLDKHELRGHINYLPQEPFI 574
Query: 425 FPGTIMENILM-ANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQL 483
F G+IMEN+L+ A P +ED+IR + I D I K+ +G+ T E+G +S G++Q
Sbjct: 575 FSGSIMENLLLGAKPGTTQEDIIRAVEIAEIKDDIEKMSQGFGTELAESGN-ISGGQKQR 633
Query: 484 ISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKV 543
I+LARA+L D ++ILDE+ S++D TE+ + + ++KL E +T I +AHRL+I++ D++
Sbjct: 634 IALARAILVDSPVLILDESTSNLDVLTEKKIIDNLMKLTE-KTIIFVAHRLTISQRVDRI 692
Query: 544 IVVDDGRIVEEGSPGELLSRKGYFYKLY 571
+ + G+I+E+G+ LL G++ L+
Sbjct: 693 LTMQSGKIIEDGTHDTLLKAGGFYASLF 720
>gb|AAA91199.1| (L76468) ABC-transporter [Gorilla gorilla]
Length = 748
Score = 247 bits (625), Expect = 2e-64
Identities = 161/563 (28%), Positives = 298/563 (52%), Gaps = 16/563 (2%)
Query: 19 SERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY----KELGFIAMLYLLSLVA 74
SE R L++ +V +V S+L +A P+ D + G + L +++L + S V
Sbjct: 182 SETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSVLTIASAVL 241
Query: 75 QWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVND 134
++ + Y G V +L+ ++ +L+ ++FF+ TG++ SR+ DT+ ++D
Sbjct: 242 EFVGDGI---YNNTMGH-VHSHLQGEVFGAVLRQEMEFFQQNQTGNITSRVTEDTSTLSD 297
Query: 135 VLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
L L L ++ ++ ML V LT+VTL ++PL+ ++ G + + R
Sbjct: 298 SLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQLLEVQVR 357
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
+ +AK S V E+++ + T+R+F E+ ++F + E + A+ + +I
Sbjct: 358 ESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSI 417
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
+ +L + ++ GG L GAVS G +V F+ Y +F + ++S+Y +Q A+ + E+
Sbjct: 418 SGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEK 477
Query: 315 IYEILDDENVEDYEGISVE-KLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAI 370
I+E LD G+ L+G ++F++V F Y RP VL+ + + P A+
Sbjct: 478 IFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAY-PNRPDVLVLQGLTFTLHPGEVTAL 536
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG G+GK+T+A L+ Y PT G++L DG + + L +++ V QE +F ++
Sbjct: 537 VGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQ 596
Query: 431 ENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI + E++ + G H FI LP+GY+T GEAG LS G+RQ ++LARA
Sbjct: 597 ENIAYGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARA 656
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSIIIAHRLSITRFADKVIVVD 547
+++ P ++ILD+A S++D ++ V+ + + E R+ ++I LS+ AD ++ ++
Sbjct: 657 LIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLE 716
Query: 548 DGRIVEEGSPGELLSRKGYFYKL 570
G I E G+ +L+ +KG ++ +
Sbjct: 717 GGAIREGGTHQQLMEKKGCYWAM 739
>gb|AAA91198.1| (L76470) ABC-transporter [Gorilla gorilla]
Length = 747
Score = 247 bits (623), Expect = 3e-64
Identities = 161/563 (28%), Positives = 297/563 (52%), Gaps = 16/563 (2%)
Query: 19 SERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY----KELGFIAMLYLLSLVA 74
SE R L++ +V +V S+L +A P+ D + G + L +++L + S V
Sbjct: 182 SETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAVL 241
Query: 75 QWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVND 134
++ + Y G V +L+ ++ +L+ +FF+ TG++ SR+ DT+ ++D
Sbjct: 242 EFVGDGI---YNNTMGH-VHSHLQGEVFGAVLRQETEFFQQNQTGNITSRVTEDTSTLSD 297
Query: 135 VLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
L L L ++ ++ ML V LT+VTL ++PL+ ++ G + + R
Sbjct: 298 SLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQLLEVQVR 357
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
+ +AK S V E+++ + T+R+F E+ ++F + E + A+ + +I
Sbjct: 358 ESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSI 417
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
+ +L + ++ GG L GAVS G +V F+ Y +F + ++S+Y +Q A+ + E+
Sbjct: 418 SGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEK 477
Query: 315 IYEILDDENVEDYEGISVE-KLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAI 370
I+E LD G+ L+G ++F++V F Y RP VL+ + + P A+
Sbjct: 478 IFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAY-PNRPDVLVLQGLTFTLHPGEVTAL 536
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG G+GK+T+A L+ Y PT G++L DG + + L +++ V QE +F ++
Sbjct: 537 VGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQ 596
Query: 431 ENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI + E++ + G H FI LP+GY+T GEAG LS G+RQ ++LARA
Sbjct: 597 ENIAYGLTQKPTMEEITAAAVKCGAHSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARA 656
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSIIIAHRLSITRFADKVIVVD 547
+++ P ++ILD+A S++D ++ V+ + + E R+ ++I LS+ AD ++ ++
Sbjct: 657 LIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLE 716
Query: 548 DGRIVEEGSPGELLSRKGYFYKL 570
G I E G+ +L+ +KG ++ +
Sbjct: 717 GGAIREGGTHQQLMEKKGCYWAM 739
>gb|AAC12903.1| (L21205) peptide transporter [Homo sapiens]
>gi|3036970|gb|AAC12904.1| (L21206) peptide transporter
[Homo sapiens]
Length = 748
Score = 247 bits (623), Expect = 3e-64
Identities = 161/563 (28%), Positives = 298/563 (52%), Gaps = 16/563 (2%)
Query: 19 SERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY----KELGFIAMLYLLSLVA 74
SE R L++ +V +V S+L +A P+ D + G + L +++L + S V
Sbjct: 182 SETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAVL 241
Query: 75 QWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVND 134
++ + Y G V +L+ ++ +L+ +FF+ TG+++SR+ DT+ ++D
Sbjct: 242 EFVGDGI---YNNTMGH-VHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSD 297
Query: 135 VLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
L L L ++ ++ ML V LT+VTL ++PL+ ++ G + + R
Sbjct: 298 SLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQLLEVQVR 357
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
+ +AK S V E+++ + T+R+F E+ ++F + E + A+ + +I
Sbjct: 358 ESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSI 417
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
+ +L + ++ GG L GAVS G +V F+ Y +F + ++S+Y +Q A+ + E+
Sbjct: 418 SGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEK 477
Query: 315 IYEILDDENVEDYEGISVE-KLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAI 370
I+E LD G+ L+G ++F++V F Y RP VL+ + + P A+
Sbjct: 478 IFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAY-PNRPDVLVLQGLTFTLRPGEVTAL 536
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG G+GK+T+A L+ Y PT G++L DG + + L +++ V QE +F ++
Sbjct: 537 VGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQ 596
Query: 431 ENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI + E++ + G H FI LP+GY+T GEAG LS G+RQ ++LARA
Sbjct: 597 ENIAYGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARA 656
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSIIIAHRLSITRFADKVIVVD 547
+++ P ++ILD+A S++D ++ V+ + + E R+ ++I LS+ AD ++ ++
Sbjct: 657 LIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLE 716
Query: 548 DGRIVEEGSPGELLSRKGYFYKL 570
G I E G+ +L+ +KG ++ +
Sbjct: 717 GGAIREGGTHQQLMEKKGCYWAM 739
>gb|AAC72031.1| (AF047554) putative ABC transporter [Myxococcus xanthus]
Length = 709
Score = 245 bits (620), Expect = 7e-64
Identities = 164/558 (29%), Positives = 278/558 (49%), Gaps = 5/558 (0%)
Query: 22 RTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTL 81
R + + V++VG +L SP+ RV + +P LG +A + + FF +
Sbjct: 139 RAMQVGYVALVGVLTDSLLSPH--RVMLFGRRLPIGRLGLGKVAAGLVALIAGCSFFEYV 196
Query: 82 QTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLL 141
++ +LR +L+E + L F S G+ ++ + D N + ++L S
Sbjct: 197 SRILWMRAAHRITHDLRLRLYEHVQSLELKAFADTSRGNYLTLLNEDLNRI-ELLFSSTW 255
Query: 142 GGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKIS 201
G + V L+ + +P ++++A ++R Y RQ+ +
Sbjct: 256 GVWNEVAYATCSTVGFFLVSPGFAGLAAVPMPALLLLAQSLEKRIRPRYAALRQQAGVLQ 315
Query: 202 SVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVI 261
V+ ++ GI TIRAFG E+ + + S + P++ A+ +
Sbjct: 316 GVLNNNIDGIPTIRAFGAERMAARWVDEASVGFRGEQDAATQIHSSYNPVVLAAANTLRM 375
Query: 262 VVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDD 321
V G+ A +G ++ G V+ + + P+ +V + + S LA+L R+++ +
Sbjct: 376 VTALAAGFHASRGHLTPGTYVSLVILSTSLSLPMLSVARDFPHILSTLASLSRVFKAFEL 435
Query: 322 ENVEDYEGISVEK--LKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKT 379
EG +++ ++G I +V F Y G PVL ++ IP A VG+TG+GK+
Sbjct: 436 PRERRDEGAALDAGAVRGAIRVEDVRFGYHPGLPVLDGFSVDIPAGKMTAFVGETGSGKS 495
Query: 380 TIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPE 439
T+A L++RF+D G IL D D + R +R+ I YV Q+ +LF G+I +NI P+
Sbjct: 496 TLAKLLLRFHDADAGHILLDEQDIAGLRRGDVRRAIAYVGQDIFLFNGSIRDNIAFGMPD 555
Query: 440 AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVIL 499
E + + G H+FIM+LP+GY + GE G+ LS G+RQ I +ARA+L I+IL
Sbjct: 556 VGLEAIQEAAQRAGAHEFIMQLPQGYASHTGELGQKLSGGQRQRIGIARALLLRRPILIL 615
Query: 500 DEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGE 559
DE SS+D TE + A +++ GRT I++AHRLS R A ++ V++ GRI E GS E
Sbjct: 616 DEVTSSLDAVTEAQLLRAWSEVLAGRTVIVVAHRLSAVRDAHRIHVLERGRIAESGSHEE 675
Query: 560 LLSRKGYFYKLYTSQMQE 577
LL R G + + + Q+ +
Sbjct: 676 LLGRGGRYARYWDLQVNQ 693
>dbj|BAA96612.1| (AP002482) Similar to Arabidopsis thaliana chromosome 2, BAC F14M4
; putative ABC transporter (AC004411) [Oryza sativa]
Length = 1285
Score = 245 bits (620), Expect = 7e-64
Identities = 160/564 (28%), Positives = 298/564 (52%), Gaps = 25/564 (4%)
Query: 17 ALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYI--------IPGRYKELGFIAMLY 68
A +++ A++ + +G A+AN A+ + V + I I + +++ +
Sbjct: 61 AFADKTDAALMALGTLG-AVANGAALPFMTVLFGNLIDAFGGAMGIHDVVNRVSMVSLEF 119
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF-KTKSTGDLVSRIIN 127
+ +A + +Q + G++ +R+ + IL+ + FF K +TG++V R+
Sbjct: 120 IYLAIASAVASFVQVTCWMITGERQAARIRNLYLKTILRQEIAFFDKYTNTGEVVGRMSG 179
Query: 128 DTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMR 187
DT ++ D + + + +++ G + LTLV + ++P +V+ +
Sbjct: 180 DTVLIQDAMGEKVGKFIQLVVTFLGGFIVAFAQGWLLTLVMMATIPPLVVAGAVMSNVVA 239
Query: 188 RAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGI 247
+ + A+ S VVE+++ I T+ +F EK ++++K K+ +R + G+
Sbjct: 240 KMASLGQAAYAESSVVVEQTIGSIRTVASFTGEKQAVEKYNKSLKSAYKSGVREGLAAGL 299
Query: 248 FWPLMNIASLLSVIVVIAYGGYL----AYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
+ + + I YG L Y GA + V+ A + + +
Sbjct: 300 GMGTVMVLLFCGYSLGIWYGAKLILLKGYTGAKVMNVIFAVLTGSLA----LGQASPSMK 355
Query: 304 SLQSALAALERIYEILDDE-NVEDYE--GISVEKLKGEIEFRNVWFEYEKGRP---VLKD 357
+ AA +++E ++ + ++ Y G+ + ++G+IEFR+V+F Y RP + +
Sbjct: 356 AFAGGQAAAYKMFETINRKPEIDAYSTTGMKPDDIRGDIEFRDVYFSYPT-RPDEQIFRG 414
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
+L IP + VA+VG++G+GK+T+ +LI RFYDP G++L DG++ K+ + +R +IG
Sbjct: 415 FSLSIPSGTTVALVGQSGSGKSTVISLIERFYDPQLGDVLIDGVNLKEFQLRWIRSKIGL 474
Query: 418 VPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLS 477
V QE LF +I ENI A ++++ + FI K+P+G +TS GE G LS
Sbjct: 475 VSQEPVLFAASIKENIAYGKDNATDQEIRAAAELANASKFIDKMPQGLDTSVGEHGTQLS 534
Query: 478 VGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSIT 537
G++Q I++ARA+LKDP I++LDEA S++D ++E++VQ A+ ++M RT++I+AHRLS
Sbjct: 535 GGQKQRIAIARAILKDPRILLLDEATSALDAESERIVQEALDRVMTNRTTVIVAHRLSTV 594
Query: 538 RFADKVIVVDDGRIVEEGSPGELL 561
R AD + V+ G +VE+G ELL
Sbjct: 595 RNADTIAVIHQGTLVEKGPHHELL 618
Score = 222 bits (560), Expect = 8e-57
Identities = 158/529 (29%), Positives = 275/529 (51%), Gaps = 30/529 (5%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFK--TK 116
K+ F + ++L+ + + ++ + G ++++ +R EK++ +++F
Sbjct: 756 KDSQFWSSMFLVFGAVYFLSLPVSSYLFSIAGCRLIKRIRLMTFEKVVNMEIEWFDHPEN 815
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
S+G + +R+ D V ++ L + + +L +V + + +L+L+ L +PL+
Sbjct: 816 SSGAIGARLSADAAKVRGLVGDALQLVVQNTTTLIAGLVIAFVSNWELSLIILALIPLIG 875
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
+ ++ + + + S V ++V+ I T+ +F E+ V + K ++
Sbjct: 876 LNGWIQMKFIQGFSADAKMMYEEASQVANDAVSSIRTVVSFSAEEKVMDLYKKKCEGPLR 935
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLA--YKGAVSIG--------VVVAFIQ 286
+R I GI + V + +G Y A Y GA + V F+
Sbjct: 936 TGIRTGIISGIGF---------GVSFFLLFGVYAASFYAGARLVEENKTTFPKVFRVFLA 986
Query: 287 YAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYE---GISVEKLKGEIEFRN 343
A G + DS A +A+ I+ I+D ++ D G++VE L G IEF++
Sbjct: 987 LAMAAIGVSQSSTLTSDS-SKAKSAVSSIFAIVDRKSRIDPSEDAGVTVETLHGNIEFQH 1045
Query: 344 VWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDG 400
V F Y RP + +D+ L I VA+VG++G+GK+T +L+ RFYDP G IL DG
Sbjct: 1046 VSFRYPT-RPDVEIFRDLCLTIHSGKTVALVGESGSGKSTAISLLQRFYDPDVGHILLDG 1104
Query: 401 IDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANP-EAKEEDVIRVCKELGIHDFIM 459
+D +K K LR+++G V QE LF T+ NI EA E ++I K H FI
Sbjct: 1105 VDIQKFQLKWLRQQMGLVSQEPALFNDTVRANIAYGKEGEATESEIIEAAKLANAHKFIS 1164
Query: 460 KLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMI 519
+GY T+ GE G LS G++Q I++ARA++KDP I++LDEA S++D ++E++VQ+A+
Sbjct: 1165 SSHQGYGTTVGERGAQLSGGQKQRIAIARAIVKDPKILLLDEATSALDAESERVVQDALD 1224
Query: 520 KLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFY 568
++M RT++I+AHRLS + AD + VV +G I+E+G L++ K Y
Sbjct: 1225 RVMVNRTTVIVAHRLSTIQNADLIAVVKNGVIIEKGKHDTLMNIKDGAY 1273
>dbj|BAB13177.1| (AP001119) mdlB [Buchnera sp. APS]
Length = 590
Score = 245 bits (620), Expect = 7e-64
Identities = 165/573 (28%), Positives = 300/573 (51%), Gaps = 13/573 (2%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
+LKR + ++ L + + ++ + + + P ++ I++ I+ L I +
Sbjct: 20 ILKRLLIYVKPHKKKLILAFIFLLSGSTSEVLGPILISYFINN-ILSKHQLHLLIILTII 78
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQ---KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRI 125
L ++ Q L F + +F + + + LR + LQ + F ++ G ++S++
Sbjct: 79 TLFIILQILSVFLNYFQSILFNKIAVESINKLRQDVMYAALQQPISEFDSQPIGQMISKV 138
Query: 126 INDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGK 185
NDT V ++ + SI+ + I+ AM L+ + LV L +PL++ I L +
Sbjct: 139 TNDTEAVKELYDTVGPTLFRSIILIFIILFAMFTLEWHMALVALFILPLVITIMLVYQYY 198
Query: 186 MRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYM 245
R+ R +A+I++ E++ G+ I+ F +++ +++ K S + +++
Sbjct: 199 STPLLRKVRYYLAEINNKFNETINGMNVIQQFCQQRRFQEKIKKSSDLHYMSRMKILRLD 258
Query: 246 GIFWPLMNIASLLSVIVVIAYGGYLAY--KGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
G L + SLLS +++ + ++ GA +GV+ AFI Y R P+ +
Sbjct: 259 GFL--LRPLLSLLSSMILCNFMFLFSFFPVGAFEVGVLYAFITYLGRLNEPLIAITIQQS 316
Query: 304 SLQSALAALERIYEILDDENVEDYEGISVEKLK-GEIEFRNVWFEYEK-GRPVLKDVNLY 361
LQ ++ A ERI+ ++D + G + + LK G+I +NV F ++ + +L+++N+
Sbjct: 317 VLQQSIVAGERIFSLIDSPKQK--YGKNKDLLKSGKINIQNVSFYHKNCNKNILENINIK 374
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
I S VA VG TG+GK+T+ANLIM +Y G+I D IS LR+ + V Q+
Sbjct: 375 ISSKSFVAFVGHTGSGKSTLANLIMGYYPLKNGKIYLDDKSIDSISHSVLRRNVLMVQQD 434
Query: 422 TYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
+ T NI + + EE V + + + D + +PKG + GE G LSVG++
Sbjct: 435 PIVLSDTFFYNITLGR-KIPEEKVWNILDTVHLSDLVKSMPKGIYSLLGEEGNNLSVGQK 493
Query: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFAD 541
QL+++AR ++ P ++ILDEA +++D TEQL+Q ++ + + T IIIAHRLS AD
Sbjct: 494 QLLAIARVLVAYPKVLILDEATANIDSGTEQLIQKTLLSIRKNCTLIIIAHRLSTIIEAD 553
Query: 542 KVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+IV+ G+IVE G+ +LL++K +YK+Y Q
Sbjct: 554 SIIVLKKGKIVEFGTHEQLLTKKSCYYKMYKFQ 586
>sp|P57552|MDLB_BUCAI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLB
Length = 580
Score = 245 bits (620), Expect = 7e-64
Identities = 165/573 (28%), Positives = 300/573 (51%), Gaps = 13/573 (2%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
+LKR + ++ L + + ++ + + + P ++ I++ I+ L I +
Sbjct: 10 ILKRLLIYVKPHKKKLILAFIFLLSGSTSEVLGPILISYFINN-ILSKHQLHLLIILTII 68
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQ---KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRI 125
L ++ Q L F + +F + + + LR + LQ + F ++ G ++S++
Sbjct: 69 TLFIILQILSVFLNYFQSILFNKIAVESINKLRQDVMYAALQQPISEFDSQPIGQMISKV 128
Query: 126 INDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGK 185
NDT V ++ + SI+ + I+ AM L+ + LV L +PL++ I L +
Sbjct: 129 TNDTEAVKELYDTVGPTLFRSIILIFIILFAMFTLEWHMALVALFILPLVITIMLVYQYY 188
Query: 186 MRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYM 245
R+ R +A+I++ E++ G+ I+ F +++ +++ K S + +++
Sbjct: 189 STPLLRKVRYYLAEINNKFNETINGMNVIQQFCQQRRFQEKIKKSSDLHYMSRMKILRLD 248
Query: 246 GIFWPLMNIASLLSVIVVIAYGGYLAY--KGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
G L + SLLS +++ + ++ GA +GV+ AFI Y R P+ +
Sbjct: 249 GFL--LRPLLSLLSSMILCNFMFLFSFFPVGAFEVGVLYAFITYLGRLNEPLIAITIQQS 306
Query: 304 SLQSALAALERIYEILDDENVEDYEGISVEKLK-GEIEFRNVWFEYEK-GRPVLKDVNLY 361
LQ ++ A ERI+ ++D + G + + LK G+I +NV F ++ + +L+++N+
Sbjct: 307 VLQQSIVAGERIFSLIDSPKQK--YGKNKDLLKSGKINIQNVSFYHKNCNKNILENINIK 364
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
I S VA VG TG+GK+T+ANLIM +Y G+I D IS LR+ + V Q+
Sbjct: 365 ISSKSFVAFVGHTGSGKSTLANLIMGYYPLKNGKIYLDDKSIDSISHSVLRRNVLMVQQD 424
Query: 422 TYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
+ T NI + + EE V + + + D + +PKG + GE G LSVG++
Sbjct: 425 PIVLSDTFFYNITLGR-KIPEEKVWNILDTVHLSDLVKSMPKGIYSLLGEEGNNLSVGQK 483
Query: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFAD 541
QL+++AR ++ P ++ILDEA +++D TEQL+Q ++ + + T IIIAHRLS AD
Sbjct: 484 QLLAIARVLVAYPKVLILDEATANIDSGTEQLIQKTLLSIRKNCTLIIIAHRLSTIIEAD 543
Query: 542 KVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+IV+ G+IVE G+ +LL++K +YK+Y Q
Sbjct: 544 SIIVLKKGKIVEFGTHEQLLTKKSCYYKMYKFQ 576
>pir||T03514 probable secretion ATP-binding protein - Rhodobacter capsulatus
>gi|3128315|gb|AAC16167.1| (AF010496) potential
secretion ATP-binding protein [Rhodobacter capsulatus]
Length = 725
Score = 245 bits (619), Expect = 1e-63
Identities = 161/565 (28%), Positives = 281/565 (49%), Gaps = 5/565 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
F+ L +R V V++V L A P++++V ID I + L + +Y+ +
Sbjct: 158 FMPALLEQRALFGGVAVAVVAGNLIAFALPFLMQVMIDSVISSHAWNTLAAVLSVYVFLV 217
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ F+ ++ ++ G ++ + + +H +L L F+T + G +++R + T +
Sbjct: 218 LFDAAFSYVRQRLMQICGGRLDARIGAAVHAHLLSLPLSMFETTAAG-VLARNMQLTEKI 276
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLT-SVPLMVIIALYFGGKMRRAYR 191
LV L + L ++ + LL +TLV L ++ + ++A++ RR
Sbjct: 277 RHFLVGRLFQTMLDAALLPVLLTLLALLSGLMTLVVLGFALTIAGLLAVFLPALQRRLSA 336
Query: 192 ETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPL 251
+ + + +VE ++ + T++A E + TI++ +V L
Sbjct: 337 LYDAEAGRQAHLVE-TLHNMRTVKALVLEGTRRGLWETALARTIRSQWQVGELSATVSAL 395
Query: 252 MNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
++ L + V+ G G +S+G +VAF+ + R GP+ +V + + Q A A
Sbjct: 396 TSLMERLMQVAVLGLGAEQVLSGQISVGTLVAFMMLSGRVTGPLVQIVGLINEWQEAALA 455
Query: 312 LERIYEILDDENVEDYEGISVEK-LKGEIEFRNVWFEYE-KGRPVLKDVNLYIPPASKVA 369
+ + ++D E + L+G I ++ F Y P L + L I +
Sbjct: 456 VRTLRGVMDHPPERGPEVRPIRPPLRGAIRIEDLCFTYPGTATPALDHLTLDIAAGQVIG 515
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
IVG++G+GKTT+ L+ G ILYDG D + I LR+ +G V QE LF GT+
Sbjct: 516 IVGRSGSGKTTLTRLLQGIGSAQSGRILYDGNDARHIDLDHLRRSVGIVLQENVLFRGTL 575
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI +A P+A E V+R G +FI +LP+G +T E G LS G+RQ I+LARA
Sbjct: 576 RENIALARPDASHEAVLRAATLAGAAEFIDRLPQGLDTPVEEGGANLSGGQRQRIALARA 635
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
+L DP I+ILDEA S++DP++E +V + + +GRT I+++HR+S +D ++V+D G
Sbjct: 636 LLADPPILILDEATSALDPESEAVVNRNLAAIAQGRTVIVVSHRMSSLAHSDAILVLDRG 695
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQ 574
RI + LL+R + L+ Q
Sbjct: 696 RIEDFAPHAVLLARSPTYRHLWLQQ 720
>pir||I84547 mdl protein - Escherichia coli >gi|146801|gb|AAC36870.1| (L08627)
putative [Escherichia coli] >gi|739997|prf||2004284A mdl
gene [Escherichia coli]
Length = 1143
Score = 245 bits (618), Expect = 1e-63
Identities = 163/556 (29%), Positives = 289/556 (51%), Gaps = 9/556 (1%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
LKR + R+ L I V+ + +A A ++ P ++ ID+ + L +A L
Sbjct: 570 LKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPLLISYFIDNMVAKNNLP-LKVVAGLAA 628
Query: 70 LSLVAQWFFTTLQTFYTEVFGQK---VLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRII 126
+ Q F L + +F + V++ LR+ + + L+ L F T+ G ++SR+
Sbjct: 629 AYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVT 688
Query: 127 NDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKM 186
NDT V+ D+ V+ + L S + ++VAM LD ++ LV + P+++++ + +
Sbjct: 689 NDTEVIRDLYVTVVATVLRSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYS 748
Query: 187 RRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG 246
R R +A I+ ++ + G+ I+ F ++ + + S A ++ G
Sbjct: 749 TPIVRRVRAYLADINDGFKQIINGMSVIQQFRQQARFGERMGEASRSHYMARMQTLRLDG 808
Query: 247 -IFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 305
+ PL+++ S L + ++ G+ A G + +GV+ AFI Y R P+ + + L
Sbjct: 809 FLLRPLLSLFSSLILCGLLMLFGFSA-SGTIEVGVLYAFISYLGRLNEPLIELTTQQAML 867
Query: 306 QSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPA 365
Q A+ A ER++E++D + Y G IE NV F Y VL ++NL +P
Sbjct: 868 QQAVVAGERVFELMDGPR-QQYGNDDRPFTSGTIEVDNVSFAYRDDNLVLNNINLSVPSR 926
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
+ VA+VG TG+GK+T+A+L+M +Y T+GEI DG +S + + + V Q+ +
Sbjct: 927 NFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSH-TRGQGVAMVQQDPVVL 985
Query: 426 PGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLIS 485
T + N+ + + EE V + + + + D + G T GE G LSVG++QL++
Sbjct: 986 ADTFLANVTLGR-DISEERVWQALETVQLADVARSMSDGIYTPLGEQGNNLSVGQKQLLA 1044
Query: 486 LARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIV 545
LAR +++ P I+ILDEA +S+D TEQ +Q+A+ + E T ++IAHRLS A ++V
Sbjct: 1045 LARVLVETPQILILDEATASIDSGTEQAIQHALAAVREHTTLVVIAHRLSTIVDAATILV 1104
Query: 546 VDDGRIVEEGSPGELL 561
+ G+ VE+G+ +LL
Sbjct: 1105 LHRGQAVEQGTHQQLL 1120
Score = 228 bits (574), Expect = 2e-58
Identities = 137/452 (30%), Positives = 248/452 (54%), Gaps = 2/452 (0%)
Query: 97 LRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVA 156
LR + ++ + + +F+ TGDL++R ND + V G+L + S++ +++
Sbjct: 63 LREDYYRQLSRQHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMACAVLIM 122
Query: 157 MLL-LDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIR 215
M + +LTL +L +P+M I+ G + ++ + + ++ +ES+ I I+
Sbjct: 123 MSTQISWQLTLFSLLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIK 182
Query: 216 AFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGA 275
AFG E F+ + +T K LRVA F P + IA ++ ++ I G ++ +G+
Sbjct: 183 AFGLEDRQSALFAADAEDTGKKKLRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGS 242
Query: 276 VSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKL 335
+++G + +F+ Y P+ + M++ ++ AA RI +L + V + V +
Sbjct: 243 LTLGQLTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAERPVVNDGSEPVPEG 302
Query: 336 KGEIEFRNVWFEY-EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKG 394
+GE++ F Y + P L++VN + P + I G G+GK+T+ +LI R +D + G
Sbjct: 303 RGELDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPNGSGKSTLLSLIQRHFDVSPG 362
Query: 395 EILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGI 454
+I + I K+ S R + V Q +LF T+ NI + P A ++++ V + +
Sbjct: 363 DIRFHDIPLTKLQLDSWRTGLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLASV 422
Query: 455 HDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLV 514
HD I++LP+GY+T GE G +LS G++Q IS+ARA+L + +I+ILD+ALS+VD +TE +
Sbjct: 423 HDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTEHQI 482
Query: 515 QNAMIKLMEGRTSIIIAHRLSITRFADKVIVV 546
+ + + +GRT II AHRLS A ++IV+
Sbjct: 483 LHNLRQWGQGRTVIISAHRLSALTEASEIIVM 514
>gb|AAC12905.1| (L21207) peptide transporter [Homo sapiens]
Length = 748
Score = 245 bits (618), Expect = 1e-63
Identities = 160/563 (28%), Positives = 298/563 (52%), Gaps = 16/563 (2%)
Query: 19 SERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY----KELGFIAMLYLLSLVA 74
SE R L++ +V +V S+L +A P+ D + G + L +++L + S V
Sbjct: 182 SETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAVL 241
Query: 75 QWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVND 134
++ + Y G V +L+ ++ +L+ +FF+ TG+++SR+ DT+ ++D
Sbjct: 242 EFVGDGI---YNNTMGH-VHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSD 297
Query: 135 VLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
L L L ++ ++ ML V LT+VTL ++PL+ ++ G + + R
Sbjct: 298 SLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQLLEVQVR 357
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
+ +AK S V E+++ + T+R+F E+ ++F + E + A+ + +I
Sbjct: 358 ESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSI 417
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
+ +L + ++ GG L GAVS G +V F+ Y +F + ++S+Y +Q A+ + E+
Sbjct: 418 SGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQALEVLLSIYPRVQKAVGSSEK 477
Query: 315 IYEILDDENVEDYEGISVE-KLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAI 370
I+E LD G+ L+G ++F++V F Y RP VL+ + + P A+
Sbjct: 478 IFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAY-PNRPDVLVLQGLTFTLRPGEVTAL 536
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG G+GK+T+A L+ Y PT G++L DG + + L +++ V QE +F ++
Sbjct: 537 VGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQ 596
Query: 431 ENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI + E++ + G H FI LP+GY+T GEAG LS G++Q ++LARA
Sbjct: 597 ENIAYGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVGEAGSQLSGGQQQAVALARA 656
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSIIIAHRLSITRFADKVIVVD 547
+++ P ++ILD+A S++D ++ V+ + + E R+ ++I LS+ AD ++ ++
Sbjct: 657 LIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLE 716
Query: 548 DGRIVEEGSPGELLSRKGYFYKL 570
G I E G+ +L+ +KG ++ +
Sbjct: 717 GGAIREGGTHQQLMEKKGCYWAM 739
>pir||T23476 hypothetical protein K08E7.9 - Caenorhabditis elegans
>gi|3878418|emb|CAB01232.1| (Z77666) Similarity to
C.elegans multidrug resistance protein (SW:MDR1_CAEEL),
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=440.3, E-value=5.6e-129, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=494.7, E-value=2.2e>
Length = 1321
Score = 245 bits (618), Expect = 1e-63
Identities = 163/515 (31%), Positives = 264/515 (50%), Gaps = 11/515 (2%)
Query: 68 YLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIN 127
Y V W + +++ LR + + IL+ + +F T +G L +++ +
Sbjct: 142 YAAMTVGMWAAGQITVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFD 201
Query: 128 DTNVVNDVLVSGLLGGLGSILS--LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGK 185
+ V + +G LS + G IVA +LTLV L P+ +
Sbjct: 202 NLERVKEG-TGDKIGMAFQYLSQFITGFIVAFTH-SWQLTLVMLAVTPIQALCGFAIAKS 259
Query: 186 MRR-AYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIY 244
M A RET + AK VVEE+++ I T+ + + + +S E KA + ++
Sbjct: 260 MSTFAIRETL-RYAKAGKVVEETISSIRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLF 318
Query: 245 MGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDS 304
+GI + M ++ +S + G + G+++ G ++ +
Sbjct: 319 LGISFGAMQASNFISFALAFYIGVGWVHDGSLNFGDMLTTFSSVMMGSMALGLAGPQLAV 378
Query: 305 LQSALAALERIYEILDDENVEDYE---GISVEKLKGEIEFRNVWFEYEKGR--PVLKDVN 359
L +A A IYE+LD + V D G K+KG+I NV F Y P+L+ +N
Sbjct: 379 LGTAQGAASGIYEVLDRKPVIDSSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMN 438
Query: 360 LYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVP 419
L + VA+VG +G GK+TI +L++R+YD KG+I DG+D + I+ + LRK + V
Sbjct: 439 LRVNAGQTVALVGSSGCGKSTIISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVS 498
Query: 420 QETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
QE LF TI ENI + E+++ CK FI LP GY T G+ G LS G
Sbjct: 499 QEPALFNCTIEENISLGKEGITREEMVAACKMANAEKFIKTLPNGYNTLVGDRGTQLSGG 558
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
++Q I++ARA++++P I++LDEA S++D ++E +VQ A+ K +GRT+IIIAHRLS R
Sbjct: 559 QKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQALDKAAKGRTTIIIAHRLSTIRN 618
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
AD +I +G++VE G L++++G +Y L T+Q
Sbjct: 619 ADLIISCKNGQVVEVGDHRALMAQQGLYYDLVTAQ 653
Score = 217 bits (547), Expect = 3e-55
Identities = 153/531 (28%), Positives = 276/531 (51%), Gaps = 22/531 (4%)
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGD 120
F A+++L+ AQ + L TF+ + + + R+LR++L +L ++ FF + ++G
Sbjct: 795 FWALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGK 854
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
+ +R+ D + + + +++S+ I ++ L+ + +P++
Sbjct: 855 ISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMALLIIAILPIVAFGQY 914
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
G + ++ + A + E++ + T++A +E + F + K ++
Sbjct: 915 LRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDTFYENFCEKLDIPHKEAIK 974
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAY---KGAVSIGVVVAFIQYAQRF-RGPIN 296
A G+ + +S+L ++ AY LA + V + YA +
Sbjct: 975 EAFIQGLSYGC--ASSVLYLLNTCAYRMGLALIITDPPTMQPMRVLRVMYAITISTSTLG 1032
Query: 297 NVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLK--GEIEFRNVWFEYEKGRP- 353
S + A A I+ +L + D ++ EK K G++ F+NV F Y + RP
Sbjct: 1033 FATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPE-RPE 1091
Query: 354 --VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
+LK ++ + P +A+VG +G GK+T+ L+ RFYD GEI DG + K ++ +
Sbjct: 1092 IEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNPEHT 1151
Query: 412 RKRIGYVPQETYLFPGTIMENILMA-NPE----AKEEDVIRVCKELGIHDFIMKLPKGYE 466
R +I V QE LF +I ENI+ +P A+ E+ R+ IH+FI +LP+G+E
Sbjct: 1152 RSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLA---NIHNFIAELPEGFE 1208
Query: 467 TSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRT 526
T G+ G LS G++Q I++ARA++++P I++LDEA S++D ++E++VQ A+ + EGRT
Sbjct: 1209 TRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVVQEALDRAREGRT 1268
Query: 527 SIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
I+IAHRL+ AD + VV +G I+E+G+ +L+S KG +YKL QM E
Sbjct: 1269 CIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGAYYKLTQKQMTE 1319
>sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN A)
>gi|283551|pir||S27337 multidrug resistance protein A -
Caenorhabditis elegans >gi|6809|emb|CAA46190.1| (X65054)
P-glycoprotein A [Caenorhabditis elegans]
Length = 1321
Score = 244 bits (617), Expect = 2e-63
Identities = 160/492 (32%), Positives = 260/492 (52%), Gaps = 11/492 (2%)
Query: 91 QKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILS- 149
+++ LR + + IL+ + +F T +G L +++ ++ V + +G LS
Sbjct: 165 EQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEG-TGDKIGMAFQYLSQ 223
Query: 150 -LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRR-AYRETRQKIAKISSVVEES 207
+ G IVA +LTLV L P+ + M A RET + AK VVEE+
Sbjct: 224 FITGFIVAFTH-SWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETL-RYAKAGKVVEET 281
Query: 208 VAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYG 267
++ I T+ + + + +S E KA + +++GI + M ++ +S + G
Sbjct: 282 ISSIRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIG 341
Query: 268 GYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDY 327
+ G+++ G ++ + L +A A IYE+LD + V D
Sbjct: 342 VGWVHDGSLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVIDS 401
Query: 328 E---GISVEKLKGEIEFRNVWFEYEKGR--PVLKDVNLYIPPASKVAIVGKTGAGKTTIA 382
G K+KG+I NV F Y P+L+ +NL + VA+VG +G GK+TI
Sbjct: 402 SSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTII 461
Query: 383 NLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKE 442
+L++R+YD KG+I DG+D + I+ + LRK + V QE LF TI ENI +
Sbjct: 462 SLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITR 521
Query: 443 EDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEA 502
E+++ CK FI LP GY T G+ G LS G++Q I++ARA++++P I++LDEA
Sbjct: 522 EEMVAACKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEA 581
Query: 503 LSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLS 562
S++D ++E +VQ A+ K +GRT+IIIAHRLS R AD +I +G++VE G L++
Sbjct: 582 TSALDAESEGIVQQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMA 641
Query: 563 RKGYFYKLYTSQ 574
++G +Y L T+Q
Sbjct: 642 QQGLYYDLVTAQ 653
Score = 217 bits (547), Expect = 3e-55
Identities = 153/531 (28%), Positives = 276/531 (51%), Gaps = 22/531 (4%)
Query: 63 FIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGD 120
F A+++L+ AQ + L TF+ + + + R+LR++L +L ++ FF + ++G
Sbjct: 795 FWALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGK 854
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIAL 180
+ +R+ D + + + +++S+ I ++ L+ + +P++
Sbjct: 855 ISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMALLIIAILPIVAFGQY 914
Query: 181 YFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLR 240
G + ++ + A + E++ + T++A +E + F + K ++
Sbjct: 915 LRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDTFYENFCEKLDIPHKEAIK 974
Query: 241 VAIYMGIFWPLMNIASLLSVIVVIAYGGYLAY---KGAVSIGVVVAFIQYAQRF-RGPIN 296
A G+ + +S+L ++ AY LA + V + YA +
Sbjct: 975 EAFIQGLSYGC--ASSVLYLLNTCAYRMGLALIITDPPTMQPMRVLRVMYAITISTSTLG 1032
Query: 297 NVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLK--GEIEFRNVWFEYEKGRP- 353
S + A A I+ +L + D ++ EK K G++ F+NV F Y + RP
Sbjct: 1033 FATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPE-RPE 1091
Query: 354 --VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
+LK ++ + P +A+VG +G GK+T+ L+ RFYD GEI DG + K ++ +
Sbjct: 1092 IEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNPEHT 1151
Query: 412 RKRIGYVPQETYLFPGTIMENILMA-NPE----AKEEDVIRVCKELGIHDFIMKLPKGYE 466
R +I V QE LF +I ENI+ +P A+ E+ R+ IH+FI +LP+G+E
Sbjct: 1152 RSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLA---NIHNFIAELPEGFE 1208
Query: 467 TSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRT 526
T G+ G LS G++Q I++ARA++++P I++LDEA S++D ++E++VQ A+ + EGRT
Sbjct: 1209 TRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVVQEALDRAREGRT 1268
Query: 527 SIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
I+IAHRL+ AD + VV +G I+E+G+ +L+S KG +YKL QM E
Sbjct: 1269 CIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGAYYKLTQKQMTE 1319
>gb|AAC12906.1| (L21208) peptide transporter [Homo sapiens]
Length = 748
Score = 244 bits (616), Expect = 2e-63
Identities = 160/563 (28%), Positives = 297/563 (52%), Gaps = 16/563 (2%)
Query: 19 SERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRY----KELGFIAMLYLLSLVA 74
SE R L++ +V +V S+L +A P+ D + G + L +++L + S V
Sbjct: 182 SETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAVL 241
Query: 75 QWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVND 134
++ + Y G V +L+ ++ +L+ +FF+ TG+++SR+ DT+ ++D
Sbjct: 242 EFVGDGI---YNNTMGH-VHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSD 297
Query: 135 VLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETR 194
L L L ++ ++ ML V LT+VTL ++PL+ ++ G + + R
Sbjct: 298 SLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQLLEVQVR 357
Query: 195 QKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNI 254
+ +AK S V E+++ + T+R+F E+ ++F + E + A+ + +I
Sbjct: 358 ESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSI 417
Query: 255 ASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
+ +L + ++ GG L GAVS G +V F+ Y +F + ++S+Y +Q A+ + E+
Sbjct: 418 SGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEK 477
Query: 315 IYEILDDENVEDYEGISVE-KLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAI 370
I+E LD G+ L+G ++F++V F Y RP VL+ + + P A+
Sbjct: 478 IFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAY-PNRPDVLVLQGLTFTLRPGEVTAL 536
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG G+GK+T+A L+ Y PT G++L DG + + L +++ V QE +F ++
Sbjct: 537 VGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQ 596
Query: 431 ENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI + E++ + G H FI LP+GY+T EAG LS G+RQ ++LARA
Sbjct: 597 ENIAYGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARA 656
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSIIIAHRLSITRFADKVIVVD 547
+++ P ++ILD+A S++D ++ V+ + + E R+ ++I LS+ AD ++ ++
Sbjct: 657 LIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLE 716
Query: 548 DGRIVEEGSPGELLSRKGYFYKL 570
G I E G+ +L+ +KG ++ +
Sbjct: 717 GGAIREGGTHQQLMEKKGCYWAM 739
>gb|AAA20681.1| (L16958) Mdl1p [Saccharomyces cerevisiae]
Length = 696
Score = 243 bits (615), Expect = 3e-63
Identities = 171/577 (29%), Positives = 294/577 (50%), Gaps = 26/577 (4%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
+KR + E + + + ++ I+ S+ ++A P ++ +D E G + L
Sbjct: 89 IKRLFVLSKPESKYIGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNK-L 147
Query: 70 LSLVAQWFFTTLQTFYT-------------EVFGQKVLRNLRSQLHEKILQSNLDFFKTK 116
L + FFT L + +V G++++ LR++ + L + F T
Sbjct: 148 YGLTKKQFFTALGAVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTN 207
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
GDL+SR+ +D ++V + + G +I+ M L KLT V + P +
Sbjct: 208 RVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLW 267
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
+AL +G K+R R+ + + ++ V EE + TI+A+G EK + ++K
Sbjct: 268 PMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKKQVRRYAKEVRNVFH 327
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
L+ A+ G+F+ + +++ ++ G + G++++G + +F+ YA +
Sbjct: 328 IGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLF 387
Query: 297 NVVSMYDSLQSALAALERIYEILDDENV--EDY-EGISVEKLKGEIEFRNVWFEYEKGRP 353
+ S Y L A R++E+ D + + DY +G V K F+NV F Y RP
Sbjct: 388 GLSSFYSELMKGAGAAARVFELNDRKPLISSDYWKGSCVISPKTHRVFKNVSFTYPT-RP 446
Query: 354 ---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
+ KD+N+ I P V VG +G+GK+TIA+L++R+YD G I + D + + +
Sbjct: 447 KHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRK 506
Query: 411 LRKRIGYVPQETYLFPGTIMENILMA-NPEAKEED--VIRVCKELGIHDFIMKLPKGYET 467
R+ IGYV QE LF GTI++NIL PE E+D + R + F+ P G +T
Sbjct: 507 YRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQT 566
Query: 468 SAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLV-QNAMIKLMEGRT 526
G G LS G++Q I+LARA L DP ++ILDEA S++D ++E++V +N ++ G T
Sbjct: 567 MVGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGFT 626
Query: 527 SIIIAHRLSITRFADKVIVV-DDGRIVEEGSPGELLS 562
+I IAHRLS + + +VIV+ G +VE GS +L++
Sbjct: 627 TISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIA 663
>gb|AAF09091.1|AC011663_27 (AC011663) putative ABC transporter; 82503-78258 [Arabidopsis
thaliana]
Length = 659
Score = 243 bits (613), Expect = 5e-63
Identities = 154/484 (31%), Positives = 261/484 (53%), Gaps = 14/484 (2%)
Query: 102 HEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLD 161
H + ++ FF +++ GDL SR+ +D V+ V+ + L ++L G ++ +L+L
Sbjct: 182 HRNVKLLDISFFDSQTVGDLTSRLGSDCQQVSRVIGNDLNMIFRNVLQGTGALIYLLILS 241
Query: 162 VKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEK 221
L L TL ++ + +G ++ + ++ A + V +E+ + + T+R +G EK
Sbjct: 242 WPLGLCTLVICCILAAVMFVYGMYQKKTAKLIQEITASANEVAQETYSLMRTVRVYGTEK 301
Query: 222 DVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVV 281
K ++ LR + GI+ N + I+ + GG G ++ +
Sbjct: 302 QEFKRYNHWLQRLADISLRQSAAYGIWNWSFNTLYHATQIIAVLVGGLSILAGQITAEQL 361
Query: 282 VAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEF 341
F+ Y++ V SL ++ A E++++++D + +++L G IEF
Sbjct: 362 TKFLLYSEWLIYATWWVGDNLSSLMQSVGASEKVFQMMDLK-----PRTRLQRLTGHIEF 416
Query: 342 RNVWFEYEKGRPV--LKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYD 399
+V F Y V +++VN+ + P VAIVG +G+GK+T+ NL+++ Y+PT G+IL D
Sbjct: 417 VDVSFSYPSRDEVAVVQNVNISVHPGEVVAIVGLSGSGKSTLVNLLLQLYEPTSGQILLD 476
Query: 400 GIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILM-ANPEAKEEDVIRVCKELGIHDFI 458
G+ K++ K LR+RIGYV QE LF I NI + +ED+I K+ HDFI
Sbjct: 477 GVPLKELDVKWLRQRIGYVGQEPKLFRTDISSNIKYGCDRNISQEDIISAAKQAYAHDFI 536
Query: 459 MKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAM 518
LP GY T + LLS G++Q I++ARA+L+DP I+ILDEA S++D ++E V+ +
Sbjct: 537 TALPNGYNTIVDD--DLLSGGQKQRIAIARAILRDPRILILDEATSALDAESEHNVKGVL 594
Query: 519 IKL----MEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+ R+ I+IAHRLS + AD+++ +D GR+VE GS ELLS+ G + +L Q
Sbjct: 595 RSIGNDSATKRSVIVIAHRLSTIQAADRIVAMDSGRVVEMGSHKELLSKDGLYARLTKRQ 654
Query: 575 MQEV 578
V
Sbjct: 655 NDAV 658
>pir||H81855 probable cytolysin secretion ABC transporter NMA1620 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380262|emb|CAB84848.1| (AL162756) putative
cytolysin secretion ABC transporter [Neisseria
meningitidis Z2491]
Length = 742
Score = 243 bits (613), Expect = 5e-63
Identities = 159/564 (28%), Positives = 280/564 (49%), Gaps = 3/564 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + RR V+V V L L +P +V +D ++ + L +++ L+
Sbjct: 178 FIPAVIKYRRLFFEVLVVSVVLQLFALITPLFFQVVMDKVLVHRGFSTLDVVSVALLVVS 237
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + L+T+ ++ L ++L +L L +F+ + GD V+R+ +
Sbjct: 238 LFEIVLGGLRTYLFAHTTSRIDVELGARLFRHLLSLPLSYFEHRRVGDTVARVRELEQIR 297
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L S + V M LT V L S+P + + +R +
Sbjct: 298 NFLTGQALTSVLDLAFSFIFLAV-MWYYSSTLTWVVLASLPAYAFWSAFISPILRTRLND 356
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ES+ + T++A E + + + + + RV + +
Sbjct: 357 KFARNADNQSFLVESITAVGTVKAMAVEPQMTQRWDNQLAAYVASGFRVTKLAVVGQQGV 416
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ L + + G L + +++G ++AF + + P+ + ++ Q ++
Sbjct: 417 QLIQKLVTVATLWIGARLVIESKLTVGQLIAFNMLSGQVAAPVIRLAQLWQDFQQVGISV 476
Query: 313 ERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKVAIV 371
R+ +IL+ +++ ++GEI F +V F Y+ GR +L+D+NL I + IV
Sbjct: 477 ARLGDILNAPTENASSHLALPDIRGEITFEHVDFRYKADGRLILQDLNLRIRAGEVLGIV 536
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G++G+GK+T+ L+ R Y P +G +L DG D + LR+++G V QE L +I +
Sbjct: 537 GRSGSGKSTLTKLVQRLYVPAQGRVLVDGNDLALAAPAWLRRQVGVVLQENVLLNRSIRD 596
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI + + E +I K G H+FIM+LP+GY T GE G LS G+RQ I++ARA++
Sbjct: 597 NIALTDTGMPLERIIEAAKLAGAHEFIMELPEGYGTVVGEQGAGLSGGQRQRIAIARALI 656
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
+P I+I DEA S++D ++E+ + M + RT +IIAHRLS + A ++I +D GRI
Sbjct: 657 TNPRILIFDEATSALDYESERAIMQNMQAICANRTVLIIAHRLSTVKTAHRIIAMDKGRI 716
Query: 552 VEEGSPGELLSR-KGYFYKLYTSQ 574
VE G+ ELL++ GY+ LY Q
Sbjct: 717 VEAGTQQELLAKPNGYYRYLYDLQ 740
>pir||H81088 ABC transporter family protein NMB1400 [imported] - Neisseria
meningitidis >gi|7226639|gb|AAF41764.1| (AE002488) ABC
transporter family protein [Neisseria meningitidis MC58]
Length = 742
Score = 242 bits (612), Expect = 6e-63
Identities = 159/564 (28%), Positives = 280/564 (49%), Gaps = 3/564 (0%)
Query: 13 FIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSL 72
FI + RR V+V V L L +P +V +D ++ + L +++ L+
Sbjct: 178 FIPAVIKYRRLFFEVLVVSVVLQLFALITPLFFQVVMDKVLVHRGFSTLDVVSVALLVVS 237
Query: 73 VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVV 132
+ + L+T+ ++ L ++L +L L +F+ + GD V+R+ +
Sbjct: 238 LFEIVLGGLRTYLFAHTTSRIDVELGARLFRHLLSLPLSYFEHRRVGDTVARVRELEQIR 297
Query: 133 NDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
N + L L S + V M LT V L S+P + + +R +
Sbjct: 298 NFLTGQALTSVLDLAFSFIFLAV-MWYYSSTLTWVVLASLPAYAFWSAFISPILRTRLND 356
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ A S + ES+ + T++A E + + + + + RV + +
Sbjct: 357 KFARNADNQSFLVESITAVGTVKAMAVEPQMTQRWDNQLAAYVASGFRVTKLAVVGQQGV 416
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ L + + G L + +++G ++AF + + P+ + ++ Q ++
Sbjct: 417 QLIQKLVTVATLWIGARLVIESKLTVGQLIAFNMLSGQVAAPVIRLAQLWQDFQQVGISV 476
Query: 313 ERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEK-GRPVLKDVNLYIPPASKVAIV 371
R+ +IL+ +++ ++GEI F +V F Y+ GR +L+D+NL I + IV
Sbjct: 477 ARLGDILNAPTENASSHLALPDIRGEITFEHVDFRYKADGRLILQDLNLRIRAGEVLGIV 536
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIME 431
G++G+GK+T+ L+ R Y P +G +L DG D + LR+++G V QE L +I +
Sbjct: 537 GRSGSGKSTLTKLVQRLYVPEQGRVLVDGNDLALAAPAWLRRQVGVVLQENVLLNRSIRD 596
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI + + E +I K G H+FIM+LP+GY T GE G LS G+RQ I++ARA++
Sbjct: 597 NIALTDTGMPLERIIEAAKLAGAHEFIMELPEGYGTVVGEQGAGLSGGQRQRIAIARALI 656
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
+P I+I DEA S++D ++E+ + M + RT +IIAHRLS + A ++I +D GRI
Sbjct: 657 TNPRILIFDEATSALDYESERAIMQNMQAICANRTVLIIAHRLSTVKTAHRIIAMDKGRI 716
Query: 552 VEEGSPGELLSR-KGYFYKLYTSQ 574
VE G+ ELL++ GY+ LY Q
Sbjct: 717 VEAGTQQELLAKPNGYYRYLYDLQ 740
>gb|AAF58271.1| (AE003815) Mdr50 gene product [Drosophila melanogaster]
Length = 1313
Score = 242 bits (611), Expect = 8e-63
Identities = 162/498 (32%), Positives = 260/498 (51%), Gaps = 16/498 (3%)
Query: 97 LRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVA 156
+RS+ IL ++ ++ +G++ SR+ D + + D L ++ + +++ G +V
Sbjct: 179 IRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVL 238
Query: 157 MLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRA 216
+ +L+LV LTS+PL I R ++ A + V E +++GI T++A
Sbjct: 239 AFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKA 298
Query: 217 F-GKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKG- 274
F G+ K+V +V I R ++ GI + L+ S + YG L KG
Sbjct: 299 FEGEAKEVAAYKERVVAAKILNIKR-NMFSGIGFGLLWFFIYASYALAFWYGVGLVIKGY 357
Query: 275 ---------AVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVE 325
A ++ V + G + + + A A + I E + + N
Sbjct: 358 HEPAYENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAKGACAKVFHIIEQIPEINPI 417
Query: 326 DYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIA 382
D EG + + IEF+ V F+Y RP +L +NL I VA+VG +G GK+T
Sbjct: 418 DGEGKKLNEPLTTIEFKEVEFQYPT-RPEVSILNKLNLKIHRGQTVALVGPSGCGKSTCI 476
Query: 383 NLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKE 442
L+ RFYDP G +L++G + K + LR RIG V QE LF +I ENI +A
Sbjct: 477 QLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYGREDATR 536
Query: 443 EDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEA 502
E++ FI KLPKGY+T GE G LS G++Q I++ARA+++DP+I++LDEA
Sbjct: 537 EEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEA 596
Query: 503 LSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLS 562
S++D +E VQ A+ K+ GRT+II+AHRLS R AD+++V++ G +VE G+ EL+
Sbjct: 597 TSALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELME 656
Query: 563 RKGYFYKLYTSQMQEVPG 580
K +++ L T+Q+ E G
Sbjct: 657 LKDHYFNLVTTQLGEDDG 674
Score = 235 bits (593), Expect = 1e-60
Identities = 151/519 (29%), Positives = 263/519 (50%), Gaps = 9/519 (1%)
Query: 65 AMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLV 122
++ +L++ + T LQ ++ + G+++ LR + E +L+ + +F K TG L
Sbjct: 791 SLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGTGSLC 850
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+R+ D V + + SI +LA I + + L LV L P ++I
Sbjct: 851 ARLSGDAAAVQGATGQRIGTIVQSISTLALGIALSMYYEWSLGLVALAFTPFILIAFYMQ 910
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
M + + + + + + E V+ I T+ + G+E+ + + + ++ R
Sbjct: 911 RTLMAKENMGSAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEISKRNT 970
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
+ G+ + L + + YG + + G V Q I N ++
Sbjct: 971 HFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQALIMGTASIANALAFA 1030
Query: 303 DSLQSALAALERIYEILDDE-NVEDYEGISVEKL--KGEIEFRNVWFEYEKGRP--VLKD 357
++Q ++A + I+ L + ++ D G+S + +G + F V F Y VLK
Sbjct: 1031 PNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPWHSEGYVRFDKVKFSYPTRSEIQVLKG 1090
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
+ L + K+A+VG +G GK+T LI RFYD +G L D D + +S +LR ++G
Sbjct: 1091 LELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRNQLGI 1150
Query: 418 VPQETYLFPGTIMENILMANP--EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKL 475
V QE LF TI ENI + ++++I CK+ IH+FI LP GY+T GE G
Sbjct: 1151 VSQEPILFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGEKGAQ 1210
Query: 476 LSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLS 535
LS G++Q I++ARA++++P I++LDEA S++D ++E++VQ+A+ EGRT+I IAHRLS
Sbjct: 1211 LSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAASEGRTTISIAHRLS 1270
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+D + V ++G + E G +LL+ +G +Y LY Q
Sbjct: 1271 TVVHSDVIFVFENGLVCEAGDHKQLLANRGLYYTLYKLQ 1309
>gb|AAA93553.1| (L23922) P-glycoprotein 5 [Entamoeba histolytica]
Length = 1301
Score = 242 bits (610), Expect = 1e-62
Identities = 162/516 (31%), Positives = 275/516 (52%), Gaps = 36/516 (6%)
Query: 93 VLRNLRSQLHEKILQSNLDFFKTKST--GDLVSRIINDTNVVNDVLVSGLLGGLGSILSL 150
++ ++R ++ + I++ + +F K G LV+R+ +D +N + +LG + ILS
Sbjct: 791 LIGSVRRRMFKSIVKQEIGWFDRKENRVGSLVTRLSSDPTKLNGI-TGVILGHIVYILST 849
Query: 151 AGIIVAMLLL-DVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSV-VEESV 208
L D KL L + P+ +I L+F K+ +K + S + + E+V
Sbjct: 850 ICFAFGFALYYDWKLALCVIAVFPIHTLI-LFFDFKLNSMQSSPAEKAYEESGITLVEAV 908
Query: 209 AGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGG 268
++T+++ +E+ K++S + K+ + G+ L+N + LS +V AYG
Sbjct: 909 ESMKTVQSLTREEYFLKQYSLNLKKPYKSIFK----WGLILALVNAITNLSNFIVDAYGY 964
Query: 269 YLA-YKGAVSI-------GVVVAFIQYAQRFRGPINNVV----------SMYDSLQSALA 310
YL Y A ++ G F+ + + I +VV + + ++
Sbjct: 965 YLGTYLLAKNLNYTQTNQGFYQEFMDRYMKIQKAIMSVVFAAHGVGNFGEIIPDIGKSMK 1024
Query: 311 ALERIYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPA 365
A Y ++D + + G + +KGEIEF+N+ F Y VLK ++
Sbjct: 1025 AARHSYNLIDRNAKIDSSEINGNTFNDVKGEIEFKNIRFRYPTRADNEVLKGISFKADQG 1084
Query: 366 SKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLF 425
+A+VG +G GK+T L+ RFYDPT GE+L DG + K ++ K LR +IG V QE LF
Sbjct: 1085 KTIALVGASGCGKSTTIQLVERFYDPTSGEVLLDGYNIKDLNVKFLRNQIGLVGQEPVLF 1144
Query: 426 PGTIMENILMANPEAKE---EDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
++++NI PE E E + K HDFI +P+GY T G+ G LS G++Q
Sbjct: 1145 AESVIDNIKRGVPEGVEVSNEQIYAAAKMANAHDFISAMPEGYNTMVGDRGSQLSGGQKQ 1204
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
I++ARA++++P +++LDEA S++D ++E++VQ+A+ K +GRT+IIIAHRLS + AD+
Sbjct: 1205 RIAIARALIRNPKVLLLDEATSALDTQSEKIVQDALDKASKGRTTIIIAHRLSTIQNADQ 1264
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
+ V+ G+IVE+G+ EL+ KG++Y L Q V
Sbjct: 1265 ICVIMRGKIVEQGTHQELMDLKGFYYTLAMQQFGTV 1300
Score = 224 bits (564), Expect = 3e-57
Identities = 157/578 (27%), Positives = 289/578 (49%), Gaps = 33/578 (5%)
Query: 24 LAIVVVSIVGSALANLASPYILRVAIDHYIIPG-RYKELGFIAMLYLLSLVAQWFFTTLQ 82
+ +++ +V S + I+ ++H I+ G + E + + V + L+
Sbjct: 68 MMLLMGDMVNSYIYTPGDNTIIDEEVNHMIVEGVKESENKVVVKNGIYYEVISMVLSFLR 127
Query: 83 TFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLG 142
TF V Q+ +R + +L+ + ++ + +G+L +RI D D G+
Sbjct: 128 TFSLFVVSQREGIRVRRLYFKSLLRQDATWYDFQESGELTARIATDIKNYQD----GIGP 183
Query: 143 GLGSILSLAGIIVAMLLLDVK----LTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIA 198
G I + +++ +++ K L LV L +VP F + + +
Sbjct: 184 KFGMIFQIISMVITGCVIEFKKCWDLALVVLATVPFSSFSFTIFQIIGMKYETKALKVFG 243
Query: 199 KISSVVEESVAGIETIRAFGKEKDVEKE----------FSKVSTETIKAYLRVAIYMGIF 248
++ EE++ I T+++ ++ + E F+ + + + +++R ++
Sbjct: 244 AAGAIAEETIGNIRTVQSLNQKNEFIAEYQEKIKQNEHFNGIKGQCLMSWIRFSVITFFM 303
Query: 249 WPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSA 308
+ S +V+ GG KG + V+ F+ + ++ + + + L S
Sbjct: 304 IASYALGSWYGSLVIRGKGGS---KGVFAGHVLTVFLSVLSASQ-TLSMIAILLNLLFSD 359
Query: 309 LAALERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYI 362
A+ +I+ +D D + + G + G I F +V F Y RP VLK +++ I
Sbjct: 360 KASAYKIFTTIDRIPDIDCQSIGGECPTECNGNIRFVDVQFVYPT-RPSHHVLKGLDIEI 418
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
+A+VG +G GK+T LI R Y+P G + DG D ++++ K LR +IG V QE+
Sbjct: 419 KKGETIALVGASGCGKSTTIQLIQRNYEPNGGRVTLDGKDIRELNIKWLRNQIGLVGQES 478
Query: 423 YLFPGTIMENILMANPEAK---EEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
LF GTI ENI++ E + ++++I K ++F+ KL +GY+T GE G LLS G
Sbjct: 479 VLFSGTIRENIMLGAKEGETLSKDEMIECAKVANAYEFVSKLAEGYDTLIGEKGALLSGG 538
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
++Q I++ARA++++P I++LDEA S++D ++E++VQ A+ K +GRT+II+AHRL+ R
Sbjct: 539 QKQRIAIARALIRNPSILLLDEATSALDTQSEKIVQEALEKASKGRTTIIVAHRLTTVRN 598
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
AD++ V G I+E+G EL+ KG +Y L Q E
Sbjct: 599 ADQICVFHQGEIIEQGKHQELIDLKGTYYGLVKGQSME 636
>pir||T28151 probable ABC-type transport protein TAP2 - chicken
>gi|3129973|emb|CAA18971.1| (AL023516) Transport
Associated Protein 2 [Gallus gallus]
Length = 701
Score = 242 bits (610), Expect = 1e-62
Identities = 163/568 (28%), Positives = 285/568 (49%), Gaps = 12/568 (2%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYII-PGRYKELGFIAMLY 68
L+R + A E L + + +AL + PY A+D G + ++
Sbjct: 136 LRRLLALAWPEWPFLGCAFLFLALAALGETSVPYCTGRALDVLRQGDGLAAFTAAVGLMC 195
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
L S + F +T + + +LR R QL ++ +L FF+ + +L SR+ D
Sbjct: 196 LASASSSLFAGCRGGLFTFIRFRFILRT-RDQLFSSLVYRDLAFFQKTTAAELASRLTTD 254
Query: 129 TNVVNDVL---VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGK 185
+ ++VL ++ +L LG +L G+ ML L +LT++ L VPL V + +
Sbjct: 255 VTLASNVLALNINVMLRNLGQVL---GLCAFMLGLSPRLTMLALLEVPLAVTARKVYDTR 311
Query: 186 MRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYM 245
+ R A + V+ES++ IE +R F E++ E +S+V T++ +
Sbjct: 312 HQMLQRAVLDAAADTGAAVQESISSIEMVRVFNGEEEEEHRYSQVLDRTLRLRDQRDTER 371
Query: 246 GIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSL 305
IF + + L +V+ G ++G ++ G +VAFI Y + + + Y L
Sbjct: 372 AIFLLIQRVLQLAVQALVLYCGHQQLHEGTLTAGGLVAFILYQTKAGSCVQALAYSYGDL 431
Query: 306 QSALAALERIYEILDDENVEDYEGISVE-KLKGEIEFRNVWFEY--EKGRPVLKDVNLYI 362
S AA ++++ L+ E G V +L+G + F V F Y R VL+DV +
Sbjct: 432 LSNAAAACKVFDYLNWERAVGAGGTYVPTRLRGHVTFHRVSFAYPTRPERLVLQDVTFEL 491
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
P A+ G G+GK+T L+ RFY+P GE+L DG+ + + L +++ V QE
Sbjct: 492 RPGEVTALAGLNGSGKSTCVALLERFYEPGAGEVLLDGVPLRDYEHRYLHRQVALVGQEP 551
Query: 423 YLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
LF G+I +NI + +EE++I + G FI L +G+ T GE G LS G++Q
Sbjct: 552 VLFSGSIRDNIAYGMEDCEEEEIIAAARAAGALGFISALEQGFGTDVGERGGQLSAGQKQ 611
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
I++ARA+++ P ++ILDEA S++D ++ ++Q ++ RT ++I H+ + AD+
Sbjct: 612 RIAIARALVRHPTVLILDEATSALDGDSDAMLQQ-WVRNGGDRTVLLITHQPRMLEKADR 670
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKL 570
++V++ G + E G+P EL +R G + +L
Sbjct: 671 IVVLEHGTVAEMGTPAELRTRGGPYSRL 698
>emb|CAB60262.1| (AJ250862) MrsT protein [Bacillus sp. HIL-Y85/54728]
Length = 730
Score = 242 bits (610), Expect = 1e-62
Identities = 143/567 (25%), Positives = 297/567 (52%), Gaps = 7/567 (1%)
Query: 11 KRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLL 70
K +++ + R ++++++ + + + LA P++++ +DH +I F+ ++ ++
Sbjct: 148 KYYLRYIVKSRTIVSLIILFSLITQVVFLAVPFLIKYLVDHSLISKSTNSFLFLGIVVII 207
Query: 71 SLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTN 130
++ ++ ++T + +++ + E +L+ L+F++ ++TGD+ R+ N +
Sbjct: 208 AVFILGLVMFIRNYFTIKLQAIISKSISNDFVEHLLKLPLNFYENRTTGDIAMRVSN-IS 266
Query: 131 VVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAY 190
++ +++ + I++L +AML KL + + ++ + +++
Sbjct: 267 MIREIIAKNGATIVLDIITLISFFIAMLTQSFKLAFFAIGLAIIQFLLMMILIPRIKNLI 326
Query: 191 RETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWP 250
S + E++ I I++ G + + ++S + I+A+ + I
Sbjct: 327 HNDLSIQTTTQSFLVEALRAITFIKSNGLDHSILTKWSNYYDKQIEAFSQRYHLDAIMDS 386
Query: 251 LMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALA 310
+ + ++++ +G G +++G ++ F F PI ++++ Q
Sbjct: 387 ISVSIRYCAPLLLLWFGSKEVITGNLTLGGLLGFSSLGTSFLLPIASLITGMQQFQLVGD 446
Query: 311 ALERIYEILDDE--NVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKV 368
ER+ ++++ E + I E K +I+ NV F + +LK+V+L I +K+
Sbjct: 447 TFERMQDVMETEPEQINQTSIIETELSKQDIKLENVTFTHHSLH-ILKEVSLNIKSGTKL 505
Query: 369 AIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGT 428
A+VG+TG+GKTT++ +I+ Y PTKG++ Y D K ++ LRK++G V QE++LF T
Sbjct: 506 ALVGRTGSGKTTLSRIILGLYKPTKGKVFYGEQDLKNLNLYELRKQMGVVLQESFLFNDT 565
Query: 429 IMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLAR 488
I NI ++ + + K + +H+ I+++P GY T GE G +LS G+RQ I++AR
Sbjct: 566 IANNI-AGFKSLSQDKIEQAAKRVQLHEDIIRMPMGYNTIIGENGSMLSGGQRQRIAIAR 624
Query: 489 AMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDD 548
A++ +P +VILDE S++D TE + K T I+I HRL ++ +D ++V+D
Sbjct: 625 AIVDNPSVVILDEITSNLDTLTEHEIDEYFAK--SNITRIVITHRLLSSQDSDLIVVLDQ 682
Query: 549 GRIVEEGSPGELLSRKGYFYKLYTSQM 575
G+IVE+G ELL +KGY+Y L+ Q+
Sbjct: 683 GKIVEKGKHQELLEKKGYYYNLWIKQV 709
>pir||T31078 probable ABC-transporter TycE - Brevibacillus brevis
>gi|2623775|gb|AAC45932.1| (AF004835) putative
ABC-transporter TycE [Brevibacillus brevis]
Length = 583
Score = 241 bits (608), Expect = 2e-62
Identities = 157/554 (28%), Positives = 277/554 (49%), Gaps = 12/554 (2%)
Query: 32 VGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQ 91
+G A +A P++ + D K+ + + F+ L F++ ++ +
Sbjct: 17 IGQAAVLVALPFVFKDLTDF----ASSKDPALLTRAIVTMAAMFLLFSLLSPFFSYIYRR 72
Query: 92 ---KVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSIL 148
+V+ N+R + +++ + +++ +GD +SR+ ND ++ L +L
Sbjct: 73 CVREVVANIRLLVFQRLSRLPFAYYEQHHSGDTMSRLGNDVQLMERAYAEQLKTLCIIML 132
Query: 149 SLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESV 208
SL G IV M LD K+ V L L + + F +RR + +Q++ + + + +
Sbjct: 133 SLVGSIVGMFALDGKIATVLLLVSTLTLYVNAQFAKSVRRIGDQMQQQLGTGTERLSDFL 192
Query: 209 AGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGG 268
AG+ I+ F +K V +++ + + + ++ + +S ++ +G
Sbjct: 193 AGLPVIKMFHLQKVVTARYTEANEQVTLSAIKQGHKHALLEGTNFFIQFVSFGGMLVFGI 252
Query: 269 YLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE-NVEDY 327
+ K + +GV+VA +Q + + +LQ +LA RI L + + Y
Sbjct: 253 MMVAKQMIGLGVLVAMVQQQMLVTLAFLQLGQVITTLQGSLAGASRIVGFLQEPLEPKRY 312
Query: 328 EGISVEKLK----GEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
E S + V F Y VL+ V+L + A+VG +G GK+T+
Sbjct: 313 EPASAPTATRIYDSMLTVEQVDFGYTADTKVLQGVSLQVGRGQMAALVGTSGGGKSTVMK 372
Query: 384 LIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEE 443
L++ +Y P+ G + G + S +R I YVPQ+ +LF GTI ENI +A EE
Sbjct: 373 LLLGYYPPSAGSLPLLGKPIGQYSIAEMRSLISYVPQDAFLFEGTIEENIRYGCLDATEE 432
Query: 444 DVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEAL 503
+VIR K HDFIM+LP GY+T GE G LS G+RQ I++ARA+LK+ I++LDEA
Sbjct: 433 EVIRASKAAYAHDFIMELPDGYQTRTGERGAKLSGGQRQRIAIARAILKNAPILLLDEAT 492
Query: 504 SSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR 563
S++D ++E VQ A+ LM+ +T ++IAHRLS AD + V+ +G+++E+G ELL++
Sbjct: 493 SALDTESEFWVQRALAALMQEKTVLVIAHRLSTIEHADMIYVLHEGKVMEQGRHAELLAQ 552
Query: 564 KGYFYKLYTSQMQE 577
G + +Y Q ++
Sbjct: 553 NGLYASMYEVQQRK 566
>pir||T30882 multidrug resistance protein 1 - Aspergillus flavus
>gi|2673947|gb|AAB88655.1| (U62931) multidrug resistance
protein 1 [Aspergillus flavus] >gi|2673949|gb|AAB88656.1|
(U62932) multidrug resistance protein 1 [Aspergillus
flavus]
Length = 1307
Score = 240 bits (606), Expect = 3e-62
Identities = 154/534 (28%), Positives = 279/534 (51%), Gaps = 18/534 (3%)
Query: 60 ELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKS 117
+ F +++L+ + ++Q +K++ RSQ IL ++ FF + +
Sbjct: 777 DANFWCLMFLMIGIVSLVLYSVQGTLFAYSSEKMVYRARSQAFRVILHQDISFFDQQENT 836
Query: 118 TGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAML----LLDVKLTLVTLTSVP 173
TG L + + T + + SG+ LG+IL ++ +VA L ++ KL LV +++VP
Sbjct: 837 TGALTATLSAGTKELTGI--SGVT--LGTILIVSVNLVASLGVALVIGWKLALVCISAVP 892
Query: 174 LMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTE 233
+++ + R R ++ + +S E+ + I T+ + E + + +
Sbjct: 893 ALLMCGFVRVWMLERFQRRAKKAYQESASSACEAASAIRTVVSLTMETEALQSYQAQLRR 952
Query: 234 TIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIG---VVVAFIQYAQR 290
+K+ + + + + + + YGG L G S+ V + + + +
Sbjct: 953 QLKSDILPIVKSSLLYASSQALPFFCMALGFWYGGSLLGHGEYSLFQFYVCFSEVIFGAQ 1012
Query: 291 FRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEK 350
G + + + A +R++ D + +G+ V ++G +EFR+V F Y
Sbjct: 1013 AAGTVFSHAPDMGKAKHAAREFKRLFSS-DTMHASRSKGVPVTSMRGLVEFRDVSFRYPS 1071
Query: 351 G--RPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISR 408
+P+L+ +NL I P VA+VG +G+GK+T L+ RFYDP KG + DG + +
Sbjct: 1072 RLEQPILRHLNLTIKPGQFVALVGASGSGKSTTIALLERFYDPLKGGVYVDGKNIITLEM 1131
Query: 409 KSLRKRIGYVPQETYLFPGTIMENILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYE 466
S R + + QE LF GTI ENIL+ + P ++ +++ CK+ I+DFI+ LP+G+
Sbjct: 1132 SSYRSHLALISQEPTLFQGTIRENILLGSNTPHVTDDFLVKACKDANIYDFILSLPQGFN 1191
Query: 467 TSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRT 526
T G G +LS G++Q I++ARA++++P I++LDEA S++D ++E++VQ A+ GRT
Sbjct: 1192 TIVGNKGGMLSGGQKQRIAIARALIRNPKILLLDEATSALDSESEKVVQAALDAAARGRT 1251
Query: 527 SIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
+I +AHRLS + AD + V+D G +VE G+ ELL +KG +Y+L Q + G
Sbjct: 1252 TIAVAHRLSTIQRADLIYVLDQGEVVESGTHRELLRKKGRYYELVHLQNPDATG 1305
Score = 217 bits (548), Expect = 2e-55
Identities = 167/557 (29%), Positives = 282/557 (49%), Gaps = 61/557 (10%)
Query: 46 RVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKI 105
R+ DH+ + EL + ++ A++ L T G V++ +R + + I
Sbjct: 97 RITYDHF-----HHELTKNVVYFIYLGAAEFVAIYLATVGFIYTGDHVVQQIRVEYFQAI 151
Query: 106 LQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILS-LAGIIVAMLLLDVKL 164
L+ N+ FF T G++ +RI DTN++ D G+ +G L+ L+ + A ++ +K
Sbjct: 152 LRQNIAFFDTLGAGEITTRITADTNLIQD----GISEKVGLALTGLSTFVTAFIIAYIKN 207
Query: 165 TLVTLTSVPLMVIIALYFGG---KMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEK 221
+ L ++ + L GG M ++ + + +S+ E+ + I T+ AF ++
Sbjct: 208 WKLALICSASLLALLLTMGGCSTLMLIFSKKALEYQGRGASMAEDILDSIRTVAAFNAQE 267
Query: 222 DVEKEF-------------SKVSTETIKAYLRVAIYMGI---FWPLMNIASLLSVIVVIA 265
+ +++ SKV + L +Y+ FW M L+ I I
Sbjct: 268 TLARKYESHLKDAEGPGMKSKVIFAIMVGALLCIMYLNYGLGFW--MGSRFLVEGISNIK 325
Query: 266 YGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVE 325
G L A+ +G + NV +L A+AA ++Y +D ++
Sbjct: 326 AGDVLTIMMAIILGSY------------NLGNVAPNGQALSDAVAAASKLYGTIDRQSPL 373
Query: 326 DY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKT 379
D +G ++E ++G I +N+ Y RP V D++ YIP A VG +G+GK+
Sbjct: 374 DALSDQGKTLEFVRGNIVLQNIRHVYPS-RPEVTVAHDLSCYIPAGKTTAFVGPSGSGKS 432
Query: 380 TIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENIL--MAN 437
TI +L+ RFYDP G I+ DG D + ++ + LR+++ V QE LF TI ENI +
Sbjct: 433 TIISLLERFYDPVAGTIMLDGHDIQTLNLRWLRQQMSLVSQEPRLFATTIAENIRYGIIG 492
Query: 438 PEAKEEDVIRVCKEL-------GIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
++E + K + HDFIM LP GY+T+ LS G++Q I++ARA+
Sbjct: 493 SRFEKESTYEIRKRVEAAARMANAHDFIMALPNGYDTNIESFS--LSGGQKQRIAIARAI 550
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+KDP I++LDEA S++D K+E+LVQ A+ K +GRT+I+IAHRLS + A +IV+ +G+
Sbjct: 551 IKDPKILLLDEATSALDTKSEKLVQAALDKASKGRTTIVIAHRLSTIQKAYNIIVLANGQ 610
Query: 551 IVEEGSPGELLSRKGYF 567
IVE+G L+ R+G +
Sbjct: 611 IVEQGPHEHLMDRRGIY 627
>pir||S30328 multidrug resistance protein 2 - Entamoeba histolytica
>gi|158973|gb|AAA29113.1| (M88598) P-glycoprotein-2
[Entamoeba histolytica]
Length = 1310
Score = 240 bits (605), Expect = 4e-62
Identities = 161/525 (30%), Positives = 278/525 (52%), Gaps = 48/525 (9%)
Query: 90 GQKVLRNLRSQLHEKILQSNLDFFKTKST--GDLVSRIINDTNVVNDVLVSG-LLGGLGS 146
G K++ +R ++ I+ N+ +F K G L +R+ +D + + SG +G +
Sbjct: 797 GFKMIGRVRKDMYHSIMHQNISWFDRKENMVGSLTTRLASDPTTLQGI--SGERVGNVIH 854
Query: 147 ILSLAGIIVAMLLL-DVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSV-V 204
I+S G + + D K++L + P+++++ ++ GK+ Q + S + +
Sbjct: 855 IISTIGFALGIAFYYDWKVSLAVMAVSPVLIVV-VFINGKLNSLEACPAQAAYEKSGITL 913
Query: 205 EESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFW-PLMNIASLLSVI-- 261
E+V + T+++ +E+ + F E ++ IY W PL++I L+ +
Sbjct: 914 VEAVESVRTVQSLTREEHFYEVFKDALREP-----KIGIYK---WAPLLSIFMCLTTLLT 965
Query: 262 -VVIAYGGYLAY-----KGAVSIGVVVAFIQYAQRFRG-------------PINNVVSMY 302
V+ YG Y+ K + V I+++ RF + N+ ++
Sbjct: 966 QVMNPYGFYIGTYLIKKKSNYDLPVPDFMIEFSDRFEEMQKAIMAVIFAAQAVGNLGNIV 1025
Query: 303 DSLQSALAALERIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLK 356
+ A+ A + Y+++D + D EG + +KGEIEF+++ F Y RP VLK
Sbjct: 1026 PDIGKAVRAAKNTYDVIDRKPTIDCYSEEGETFNDVKGEIEFKDICFRYPT-RPDNSVLK 1084
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
++ + VA+VG +G GK+T LI RFYDPT G++L DG + K ++ LR +IG
Sbjct: 1085 GISFKVEQGKTVALVGASGCGKSTSVQLIERFYDPTHGDVLLDGHNIKDLNIHFLRSQIG 1144
Query: 417 YVPQETYLFPGTIMENILMANP---EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAG 473
V QE LF ++M+NI P E E + K HDFI +P+GY T G+ G
Sbjct: 1145 MVGQEPVLFAESVMDNIRRGVPKGVEVSNEQIYAAAKMANAHDFISAMPEGYNTMVGDRG 1204
Query: 474 KLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHR 533
+S G++Q I++ARA++++P +++LDEA S++D ++E++VQ+A+ K +GRT+I+IAHR
Sbjct: 1205 AQISGGQKQRIAIARALIRNPKVLLLDEATSALDSESEKIVQDALDKAAKGRTTIVIAHR 1264
Query: 534 LSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
LS + AD++ V+ GRI E G+ ELL KG++Y L Q V
Sbjct: 1265 LSTIQNADQICVIMRGRIAERGTHQELLDLKGFYYTLAMQQFGTV 1309
Score = 220 bits (555), Expect = 3e-56
Identities = 152/518 (29%), Positives = 255/518 (48%), Gaps = 30/518 (5%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
L TF V ++ N+R +L+ + ++ +G+L SRI +D + D G+
Sbjct: 138 LMTFCFFVMSERQGINIRMLYFRALLRQDAGWYDFHESGELTSRIASDVQQIQD----GM 193
Query: 141 LGGLGSILSLAGIIVAMLLL----DVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQK 196
G I +A + D LTLV ++ P +V+ + +
Sbjct: 194 SQKFGIIFQTTTSFIAGYAIGFAKDWDLTLVIMSMSPFIVLSMTLLAVFATKFTVLGEES 253
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMG---------I 247
+ ++ E ++ + T+ + G+E EF ++ E I+ R + G +
Sbjct: 254 LGNAGAIAEATIGNMRTVHSLGQEH----EFCEMYNEKIRVVDRYNVLKGLTVGLGLGAV 309
Query: 248 FWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQS 307
+ +M SL S + G K + V++ FI +G ++ + + +
Sbjct: 310 MFFIMGAFSLGSWYASVVLRGKGGKKNVTAGDVMIVFICVLIATQG-LSIIAIPLNIFAT 368
Query: 308 ALAALERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYI 362
A A+ RIY+ +D D + G + G I +V F Y + +L ++L I
Sbjct: 369 AKASAYRIYQTIDRIPDIDCRSTAGECPTECNGNITLEDVQFRYPTRPTKQILGGLDLEI 428
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
VA+VG +G GK+T L+ R YDP G + DG D + ++ K LR +IG V QE
Sbjct: 429 KKGQTVALVGASGCGKSTTIQLVQRNYDPVGGSVKLDGKDLRDLNIKWLRNQIGLVGQEP 488
Query: 423 YLFPGTIMENILMANPEAK---EEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVG 479
LF TI ENI++ + + EE++I K H+FI LP+GY+T GE G LS G
Sbjct: 489 ILFACTIRENIMLGARDGETPTEEEMIECAKMANAHEFISHLPEGYDTMVGEKGAALSGG 548
Query: 480 ERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRF 539
++Q I++ARA+++ P I++LDEA S++D ++E++VQ A+ K +GRT+I++AHRL+ R
Sbjct: 549 QKQRIAIARALIRKPTILLLDEATSALDTQSEKIVQQALEKASQGRTTIVVAHRLTTVRN 608
Query: 540 ADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
A ++ V G I+E+G+ EL+ KG +Y L Q E
Sbjct: 609 ASRICVFHQGEIIEQGTHQELMDLKGTYYGLVKRQSME 646
>gi|6323217 ATP-binding cassette (ABC) transporter family member; Mdl1p
[Saccharomyces cerevisiae]
>gi|1346512|sp|P33310|MDL1_YEAST ATP-DEPENDENT PERMEASE
MDL1 >gi|1078101|pir||S51433 MDL1 protein - yeast
(Saccharomyces cerevisiae) >gi|577195|gb|AAB67455.1|
(U17246) Mdl1p [Saccharomyces cerevisiae]
Length = 695
Score = 239 bits (604), Expect = 6e-62
Identities = 167/576 (28%), Positives = 291/576 (49%), Gaps = 25/576 (4%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYL 69
+KR + E + + + ++ I+ S+ ++A P ++ +D E G + L
Sbjct: 89 IKRLFVLSKPESKYIGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNK-L 147
Query: 70 LSLVAQWFFTTLQTFYT-------------EVFGQKVLRNLRSQLHEKILQSNLDFFKTK 116
+ FFT L + +V G++++ LR++ + L + F T
Sbjct: 148 YGFTKKQFFTALGAVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTN 207
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
GDL+SR+ +D ++V + + G +I+ M L KLT V + P +
Sbjct: 208 RVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLG 267
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
+AL +G K+R R+ + + ++ V EE + TI+A+G EK+ + ++K
Sbjct: 268 AMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFH 327
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
L+ A+ G+F+ + +++ ++ G + G++++G + +F+ YA +
Sbjct: 328 IGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLF 387
Query: 297 NVVSMYDSLQSALAALERIYEILDDENV--EDYEGISVEKLKGEIEFRNVWFEYEKGRP- 353
+ S Y L A R++E+ D + + V + I F+NV F Y RP
Sbjct: 388 GLSSFYSELMKGAGAAARVFELNDRKPLIRPTIGKDPVSLAQKPIVFKNVSFTYPT-RPK 446
Query: 354 --VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
+ KD+N+ I P V VG +G+GK+TIA+L++R+YD G I + D + + +
Sbjct: 447 HQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKY 506
Query: 412 RKRIGYVPQETYLFPGTIMENILMA-NPEAKEED--VIRVCKELGIHDFIMKLPKGYETS 468
R+ IGYV QE LF GTI++NIL PE E+D + R + F+ P G +T
Sbjct: 507 RRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQTM 566
Query: 469 AGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLV-QNAMIKLMEGRTS 527
G G LS G++Q I+LARA L DP ++ILDEA S++D ++E++V +N ++ G T+
Sbjct: 567 VGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGFTT 626
Query: 528 IIIAHRLSITRFADKVIVV-DDGRIVEEGSPGELLS 562
I IAHRLS + + +VIV+ G +VE GS +L++
Sbjct: 627 ISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIA 662
>pir||T43261 multidrug resistance protein 1 - fungus (Filobasidium floriforme)
>gi|2668553|gb|AAC49889.1| (U62929) multidrug resistance
protein 1 [Filobasidiella neoformans]
>gi|2668555|gb|AAC49890.1| (U62930) multidrug resistance
protein 1 [Filobasidiella neoformans]
Length = 1408
Score = 239 bits (604), Expect = 6e-62
Identities = 160/528 (30%), Positives = 268/528 (50%), Gaps = 24/528 (4%)
Query: 67 LYLLSL-VAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRI 125
LYL+++ + + T L F V G+ + +R + +L+ + +F G++ +RI
Sbjct: 223 LYLMAIGIGMFLATWLYMFIWNVTGELNSKRIRERYLAAVLRQEIAYFDDLGAGEVATRI 282
Query: 126 INDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLL----DVKLTLVTLTSVPLMVIIALY 181
D ++V + G + + AG V +L +L ++ +P++++
Sbjct: 283 QTDCHLVQE----GTSEKVALVFQYAGTFVCGFVLAFVRSPRLAGALVSILPVIMLCGGI 338
Query: 182 FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRV 241
M + IAK S+ EE + I T++AFGKEK + +F+ ++ +
Sbjct: 339 MMTAMAKYGTAALDHIAKAGSLAEEVIGSIRTVQAFGKEKILGDKFADHIEQSKIVGRKG 398
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSM 301
+I+ G +M + + YGG L G G+V+ + +
Sbjct: 399 SIFEGFGLSIMFFVIYAAYALAFFYGGILVSNGQADSGIVINVFMSILIGSFSMAMLAPE 458
Query: 302 YDSLQSALAALERIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEK--GRPVLK 356
++ A A +++ +D D EG + L+GEI F NV F Y P+LK
Sbjct: 459 LAAVTKARGAAAKLFATIDRVPAIDSASEEGFKPDGLRGEISFENVKFHYPSRPSIPILK 518
Query: 357 DVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIG 416
A+VG +G+GK+T+ +LI RFYDP G + DG D + ++ LR++IG
Sbjct: 519 GFTTTFEAGKTFALVGASGSGKSTVVSLIERFYDPVSGVVKLDGRDIRSLNLNWLRQQIG 578
Query: 417 YVPQETYLFPGTIMENILM---------ANPEAKEEDVIRVCKELGIHDFIMKLPKGYET 467
V QE LF T+ N+ A+ E K E V + C + H+FIMKLP+GY+T
Sbjct: 579 LVSQEPTLFGTTVRGNVEHGLIGSRYENASLEEKFELVKKACVDANAHNFIMKLPQGYDT 638
Query: 468 SAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTS 527
GE G LLS G++Q +++ARA++ DP I++LDEA S++D ++E +VQ+A+ K GRT+
Sbjct: 639 MVGERGMLLSGGQKQRVAIARAIVSDPRILLLDEATSALDTQSEGIVQDALDKASRGRTT 698
Query: 528 IIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRK-GYFYKLYTSQ 574
I IAHRLS R AD++ V+ G ++E+GS +LL+ + G + +L +Q
Sbjct: 699 ITIAHRLSTIRDADRIYVMGGGEVLEQGSHNDLLANENGPYAQLVNNQ 746
Score = 226 bits (571), Expect = 4e-58
Identities = 168/595 (28%), Positives = 298/595 (49%), Gaps = 34/595 (5%)
Query: 5 SSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYII--PGRYKE-L 61
SS L R ++ +++ I ++ + + + + + A+ + I P + L
Sbjct: 818 SSFGLYARLLRMNSADKFIYIIAFIAAICAGMVYPSLAILFGKALSDFEIQDPAELRHAL 877
Query: 62 GFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTG 119
A+ Y ++ +A F Q+ G + LR +L L+ ++++F + STG
Sbjct: 878 SRSALWYFITALAAAFVIFFQSAGFSRAGWDLNGVLRKKLFTATLRHDIEWFDEERNSTG 937
Query: 120 DLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIA 179
+ S + + V + L + S +L G + L L L+ + +P++V
Sbjct: 938 AVTSNLADQPQKVQGLFGPTLGTVVQSCATLIGGCIIGLCYGPLLALIGIACIPILVS-- 995
Query: 180 LYFGGKMRR---AYRETRQKIAKISS--VVEESVAGIETIRAFGKEKDVEKEFSKVSTET 234
GG +R ++ R K +S + E+ ++T+ + +EKDV + +S+
Sbjct: 996 ---GGYIRLKVVVLKDQRMKKLHAASAHLASEAAGAVKTVASLTREKDVRRIYSEALKAP 1052
Query: 235 IKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYL----AYKGAVSIGVVVAFIQYAQR 290
+K R +I + +I ++ Y G L A S V+ I +A
Sbjct: 1053 MKLNFRTSIKSQCLFAASQ-GLTFCIIALVFYIGALWIIDAKYSTASFYTVLNSIVFASI 1111
Query: 291 FRGPINNVVSMYDSLQSALAALERIYEILDDE---NVEDYEG--ISVEKLKGEIEFRNVW 345
G NV + A ++ I+ +D+E N E EG + + + G + V
Sbjct: 1112 QAG---NVFTFVPDASKANSSAASIFRSIDNEPAINAESNEGKVLDHKHVVGHVRIEGVH 1168
Query: 346 FEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDG 403
F Y G VL+++ + +P + VA+VG +G GK+T ++ RFYDP G + DGID
Sbjct: 1169 FRYPTRPGVRVLRNLTIDVPAGTYVALVGPSGCGKSTTIQMLERFYDPLAGRVTLDGIDI 1228
Query: 404 KKISRKSLRKRIGYVPQETYLFPGTIMENILM-ANP---EAKEEDVIRVCKELGIHDFIM 459
K+++ S R +I V QE L+ GTI NIL+ AN E ++++ CK+ I+DFI+
Sbjct: 1229 KELNLASYRSQISLVSQEPTLYAGTIRFNILLGANKPIEEVTQDEIDAACKDANIYDFIV 1288
Query: 460 KLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMI 519
LP G++T G G LS G++Q I++ARA++++P +++LDEA S++D ++E++VQ A+
Sbjct: 1289 SLPDGFDTEVGGKGSQLSGGQKQRIAIARALIRNPKVLLLDEATSALDSQSEKVVQEALD 1348
Query: 520 KLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
K +GRT+I IAHRLS + +D++ +GR+ E G+ ELL++KG +Y+L Q
Sbjct: 1349 KAAKGRTTIAIAHRLSSIQHSDRIYYFSEGRVAEHGTHQELLAKKGGYYELVQMQ 1403
>pir||JE0248 ATP-binding cassette half-transporter - rat
>gi|2982567|emb|CAA05793.1| (AJ003004) ABC transporter
[Rattus norvegicus]
Length = 836
Score = 239 bits (604), Expect = 6e-62
Identities = 162/518 (31%), Positives = 266/518 (51%), Gaps = 33/518 (6%)
Query: 77 FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVL 136
F + L+TF Q R + +L + + +L + + TG+++ + T+ V +L
Sbjct: 325 FVSNLRTFLWIRVQQFTSRGVELRLFSHLHELSLRWHLGRRTGEVLRIVDRGTSSVTGLL 384
Query: 137 ---VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALY---FGGKMRRAY 190
V ++ L I+ GII + + L+ + L +I+ + + K RR
Sbjct: 385 SYLVFNIIPTLADII--IGIIYFSMFFNAWFGLIVFLCMSLYLILTIMVTEWRAKFRRDM 442
Query: 191 RETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWP 250
T++ + +V +S+ ET++ + E E + +K + G+ W
Sbjct: 443 N-TQENATRARAV--DSLLNFETVKYYNAEG---YELERYREAILK-------FQGLEWK 489
Query: 251 LMNIASLLSVI--VVIAYG--------GYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
LL+ +VI +G Y + + +G V F Y + P+N +
Sbjct: 490 STASLVLLNQTQNMVIGFGLLAGSLLCAYFVSERRLQVGDFVLFGTYITQLYMPLNWFGT 549
Query: 301 MYDSLQSALAALERIYEILDDEN-VEDYEGISVEKL-KGEIEFRNVWFEYEKGRPVLKDV 358
Y +Q+ +E ++++L +E V+D G + KG +EF NV F Y GR L+DV
Sbjct: 550 YYRMIQTNFIDMENMFDLLKEETEVKDVPGAGPLRFHKGRVEFENVHFSYADGRETLQDV 609
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+ + P VA+VG +GAGK+TI L+ RFYD + G I DG D ++++ SLR IG V
Sbjct: 610 SFTVMPGQTVALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQISLRSHIGVV 669
Query: 419 PQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
PQ+T LF TI NI A + ++ + GIHD I+ P+GYET GE G LS
Sbjct: 670 PQDTVLFNDTIANNIRYGRVTAGDSEIQAAAQAAGIHDAILSFPEGYETQVGERGLKLSG 729
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
GE+Q +++AR +LK PDI++LDEA S++D E+ +Q ++ K+ RT+I++AHRLS
Sbjct: 730 GEKQRVAIARTILKAPDIILLDEATSALDTSNERAIQASLAKVCTNRTTIVVAHRLSTVV 789
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQ 576
AD+++V+ DG I+E G LLSR G + +++ Q Q
Sbjct: 790 NADQILVIKDGCIIERGRHEALLSRGGVYAEMWQLQQQ 827
>pir||T14805 hypothetical protein F15J5.20 - Arabidopsis thaliana
>gi|5816991|emb|CAB53646.1| (AL110123) multidrug
resistance protein/P-glycoprotein-like [Arabidopsis
thaliana]
Length = 1222
Score = 239 bits (604), Expect = 6e-62
Identities = 161/569 (28%), Positives = 291/569 (50%), Gaps = 36/569 (6%)
Query: 17 ALSERRTLAIVVVSIVGSALANLASPYILRVA-----------IDHYIIPGRYKELGFIA 65
+ +++ + ++ V + +A L P++ + DH + +E+ +A
Sbjct: 23 SFADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAFGTTDPDHMV-----REVWKVA 77
Query: 66 MLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS-TGDLVSR 124
+ ++ V LQ V G++ +R + IL+ ++ +F T++ TG+++ R
Sbjct: 78 VKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYLKTILRQDIGYFDTETNTGEVIGR 137
Query: 125 IINDTNVVNDVLVSGLLGGLGSILS--LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+ DT ++ D + +G +L L G +A + L V + +PL+VI
Sbjct: 138 MSGDTILIQDAM-GEKVGKFTQLLCTFLGGFAIAFYKGPL-LAGVLCSCIPLIVIAGAAM 195
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
M + + A+ +VVE++V I T+ AF EK +++ K ++
Sbjct: 196 SLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEKQATEKYESKLEIAYKTVVQQG 255
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYL----AYKGAVSIGVVVAFIQYAQRFRGPINNV 298
+ G M S + + YG L Y G I V+ A + +
Sbjct: 256 LISGFGLGTMLAVIFCSYGLAVWYGAKLIMEKGYNGGQVINVIFAVLTGGMS----LGQT 311
Query: 299 VSMYDSLQSALAALERIYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP-- 353
++ + AA +++E + + D G +E ++G+IE ++V+F Y RP
Sbjct: 312 SPSLNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRGDIELKDVYFRYP-ARPDV 370
Query: 354 -VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
+ +L++P VA+VG++G+GK+T+ +LI RFYDP G++L D ID KK+ K +R
Sbjct: 371 QIFAGFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQVLIDNIDLKKLQLKWIR 430
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEA 472
+IG V QE LF TI ENI +A ++++ + FI KLP+G +T GE
Sbjct: 431 SKIGLVSQEPVLFATTIKENIAYGKEDATDQEIRTAIELANAAKFIDKLPQGLDTMVGEH 490
Query: 473 GKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAH 532
G +S G++Q +++ARA+LK+P I++LDEA S++D ++E++VQ+A++ LM RT++++AH
Sbjct: 491 GTQMSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQDALVNLMSNRTTVVVAH 550
Query: 533 RLSITRFADKVIVVDDGRIVEEGSPGELL 561
RL+ R AD + VV G+IVE+G+ E++
Sbjct: 551 RLTTIRTADVIAVVHQGKIVEKGTHDEMI 579
Score = 180 bits (453), Expect = 3e-44
Identities = 137/517 (26%), Positives = 245/517 (46%), Gaps = 47/517 (9%)
Query: 44 ILRVAIDHYIIPGRY--KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQL 101
+L +I+ + P + K+ F A++Y+ + + + ++ + G K+++ +RS
Sbjct: 706 LLSSSINMFYEPAKILKKDSHFWALIYIALGLTNFVMIPVPNYFFGIAGGKLIKRIRSMC 765
Query: 102 HEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLL------------------GG 143
+K++ + +F + SR N ++N ++ L+
Sbjct: 766 FDKVVHQEISWFDDTAN----SRYYNFIYIINRRILYVLILIFICVLLPPVRLERECSTD 821
Query: 144 LGSILSLAGIIVAMLLLDVK---------------LTLVTLTSVPLMVIIALYFGGKMRR 188
++ SL G +A+++ ++ L L+ L P +VI +
Sbjct: 822 ASTVRSLVGDALALIVQNIATVTTGLIIAFTANWILALIVLALSPFIVIQGYAQTKFLTG 881
Query: 189 AYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIF 248
+ + + S V ++V+ I T+ +F E+ V + + K +R+ + G
Sbjct: 882 FSADAKAMYEEASQVANDAVSSIRTVASFCAEEKVMDLYQQKCDGPKKNGVRLGLLSGAG 941
Query: 249 WPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSA 308
+ V G L G + G V ++ +M A
Sbjct: 942 FGFSFFFLYCINCVCFVSGAGLIQIGKATFGEVFKVFFALTIMAIGVSQTSAMAPDSNKA 1001
Query: 309 LAALERIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYI 362
+ I++ILD D EG +++ + G+IEFR+V F Y RP + +D+ L I
Sbjct: 1002 KDSAASIFDILDSTPKIDSSSDEGTTLQNVNGDIEFRHVSFRYPM-RPDVQIFRDLCLTI 1060
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
P VA+VG++G+GK+T+ ++I RFY+P G+IL D ++ + LR+++G V QE
Sbjct: 1061 PSGKTVALVGESGSGKSTVISMIERFYNPDSGKILIDQVEIQTFKLSWLRQQMGLVSQEP 1120
Query: 423 YLFPGTIMENILMANPE-AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
LF TI NI A EE++I K H+FI LP+GY+TS GE G LS G++
Sbjct: 1121 ILFNETIRSNIAYGKTGGATEEEIIAAAKAANAHNFISSLPQGYDTSVGERGVQLSGGQK 1180
Query: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAM 518
Q I++ARA+LKDP I++LDEA S++D ++E++VQ+A+
Sbjct: 1181 QRIAIARAILKDPKILLLDEATSALDAESERVVQDAL 1217
>emb|CAB78807.1| (AL161547) multidrug resistance protein/P-glycoprotein-like
[Arabidopsis thaliana]
Length = 1323
Score = 239 bits (604), Expect = 6e-62
Identities = 161/569 (28%), Positives = 291/569 (50%), Gaps = 36/569 (6%)
Query: 17 ALSERRTLAIVVVSIVGSALANLASPYILRVA-----------IDHYIIPGRYKELGFIA 65
+ +++ + ++ V + +A L P++ + DH + +E+ +A
Sbjct: 23 SFADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAFGTTDPDHMV-----REVWKVA 77
Query: 66 MLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKS-TGDLVSR 124
+ ++ V LQ V G++ +R + IL+ ++ +F T++ TG+++ R
Sbjct: 78 VKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYLKTILRQDIGYFDTETNTGEVIGR 137
Query: 125 IINDTNVVNDVLVSGLLGGLGSILS--LAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+ DT ++ D + +G +L L G +A + L V + +PL+VI
Sbjct: 138 MSGDTILIQDAM-GEKVGKFTQLLCTFLGGFAIAFYKGPL-LAGVLCSCIPLIVIAGAAM 195
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
M + + A+ +VVE++V I T+ AF EK +++ K ++
Sbjct: 196 SLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEKQATEKYESKLEIAYKTVVQQG 255
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYL----AYKGAVSIGVVVAFIQYAQRFRGPINNV 298
+ G M S + + YG L Y G I V+ A + +
Sbjct: 256 LISGFGLGTMLAVIFCSYGLAVWYGAKLIMEKGYNGGQVINVIFAVLTGGMS----LGQT 311
Query: 299 VSMYDSLQSALAALERIYEILDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP-- 353
++ + AA +++E + + D G +E ++G+IE ++V+F Y RP
Sbjct: 312 SPSLNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRGDIELKDVYFRYP-ARPDV 370
Query: 354 -VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
+ +L++P VA+VG++G+GK+T+ +LI RFYDP G++L D ID KK+ K +R
Sbjct: 371 QIFAGFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQVLIDNIDLKKLQLKWIR 430
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEA 472
+IG V QE LF TI ENI +A ++++ + FI KLP+G +T GE
Sbjct: 431 SKIGLVSQEPVLFATTIKENIAYGKEDATDQEIRTAIELANAAKFIDKLPQGLDTMVGEH 490
Query: 473 GKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAH 532
G +S G++Q +++ARA+LK+P I++LDEA S++D ++E++VQ+A++ LM RT++++AH
Sbjct: 491 GTQMSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQDALVNLMSNRTTVVVAH 550
Query: 533 RLSITRFADKVIVVDDGRIVEEGSPGELL 561
RL+ R AD + VV G+IVE+G+ E++
Sbjct: 551 RLTTIRTADVIAVVHQGKIVEKGTHDEMI 579
Score = 211 bits (532), Expect = 2e-53
Identities = 152/554 (27%), Positives = 271/554 (48%), Gaps = 47/554 (8%)
Query: 44 ILRVAIDHYIIPGRY--KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQL 101
+L +I+ + P + K+ F A++Y+ + + + ++ + G K+++ +RS
Sbjct: 706 LLSSSINMFYEPAKILKKDSHFWALIYIALGLTNFVMIPVPNYFFGIAGGKLIKRIRSMC 765
Query: 102 HEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLL------------------GG 143
+K++ + +F + SR N ++N ++ L+
Sbjct: 766 FDKVVHQEISWFDDTAN----SRYYNFIYIINRRILYVLILIFICVLLPPVRLERECSTD 821
Query: 144 LGSILSLAGIIVAMLLLDVK---------------LTLVTLTSVPLMVIIALYFGGKMRR 188
++ SL G +A+++ ++ L L+ L P +VI +
Sbjct: 822 ASTVRSLVGDALALIVQNIATVTTGLIIAFTANWILALIVLALSPFIVIQGYAQTKFLTG 881
Query: 189 AYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIF 248
+ + + S V ++V+ I T+ +F E+ V + + K +R+ + G
Sbjct: 882 FSADAKAMYEEASQVANDAVSSIRTVASFCAEEKVMDLYQQKCDGPKKNGVRLGLLSGAG 941
Query: 249 WPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSA 308
+ V G L G + G V ++ +M A
Sbjct: 942 FGFSFFFLYCINCVCFVSGAGLIQIGKATFGEVFKVFFALTIMAIGVSQTSAMAPDSNKA 1001
Query: 309 LAALERIYEILDDENVEDY---EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYI 362
+ I++ILD D EG +++ + G+IEFR+V F Y RP + +D+ L I
Sbjct: 1002 KDSAASIFDILDSTPKIDSSSDEGTTLQNVNGDIEFRHVSFRYPM-RPDVQIFRDLCLTI 1060
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
P VA+VG++G+GK+T+ ++I RFY+P G+IL D ++ + LR+++G V QE
Sbjct: 1061 PSGKTVALVGESGSGKSTVISMIERFYNPDSGKILIDQVEIQTFKLSWLRQQMGLVSQEP 1120
Query: 423 YLFPGTIMENILMANPE-AKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGER 481
LF TI NI A EE++I K H+FI LP+GY+TS GE G LS G++
Sbjct: 1121 ILFNETIRSNIAYGKTGGATEEEIIAAAKAANAHNFISSLPQGYDTSVGERGVQLSGGQK 1180
Query: 482 QLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFAD 541
Q I++ARA+LKDP I++LDEA S++D ++E++VQ+A+ ++M RT++++AHRL+ + AD
Sbjct: 1181 QRIAIARAILKDPKILLLDEATSALDAESERVVQDALDRVMVNRTTVVVAHRLTTIKNAD 1240
Query: 542 KVIVVDDGRIVEEG 555
+ VV +G I E+G
Sbjct: 1241 VIAVVKNGVIAEKG 1254
>pir||F82726 ABC transporter ATP-binding protein XF1081 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106031|gb|AAF83891.1|AE003944_8 (AE003944) ABC
transporter ATP-binding protein [Xylella fastidiosa]
Length = 589
Score = 239 bits (603), Expect = 7e-62
Identities = 152/562 (27%), Positives = 293/562 (52%), Gaps = 11/562 (1%)
Query: 26 IVVVSIVGSALANLASPYILRVA--IDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQT 83
++VV+ G+ L +A L + I + R +E +A+ L +V + +
Sbjct: 30 LLVVAACGALLEAVAGSTFLALMKPITNETFIERNRE---VALWLPLGIVGLFLLRGIAG 86
Query: 84 FYTEVF----GQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSG 139
+ T++ + + R+ R + K + F + ++ R+ +D+ V ++
Sbjct: 87 YITDMAMGRAARSIARDFRVCVLTKYFRLPGSRFDGEPVASMLVRLGSDSEQVAHAVIDA 146
Query: 140 LLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAK 199
+ + L + G +V ML +TL L PL+ + + RR ++ A+
Sbjct: 147 MKVMVQQTLQVIGALVVMLWYSWTVTLAILLVAPLLAWVMQRVAKRYRRISHHIQESNAQ 206
Query: 200 ISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLS 259
+ +++++ + ++ + ++ + +++++ + ++V + + + +
Sbjct: 207 LMQAADQALSNYQDVKVYAAQESELERYARLANINLGLAIKVESTRSLSSAAVQLLGAVG 266
Query: 260 VIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEIL 319
+ +++ G+ A G +S G V+ + + + ++ + LQS +A+ +R++ +L
Sbjct: 267 LAMLLLIAGHEALAGRLSPGDFVSLMTSMIAVIPALKQLTNVQNMLQSGIASAQRLFSVL 326
Query: 320 DDENVEDYEGISVEKLKGEIEFRNVWFEYE-KGRPVLKDVNLYIPPASKVAIVGKTGAGK 378
D + D + + +G IEFR + Y + PVL V+ P + AIVG++G+GK
Sbjct: 327 DSPDELDTGRRPLGRARGFIEFRGITARYPGRSAPVLDSVSFVAAPGTVTAIVGRSGSGK 386
Query: 379 TTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANP 438
+++ LI RFY+P G+IL DG + LR++I V Q+ LF G+I ENI
Sbjct: 387 SSLIKLIPRFYEPESGQILLDGHPLQDYLLADLRRQIALVGQQVMLFDGSIAENIAYGEM 446
Query: 439 -EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIV 497
+ E++ RV + DF+ +LP+G + G G LS G+RQ +++ARAMLKD I+
Sbjct: 447 RQVVSEEIERVVVDANAQDFVNQLPEGLQFQVGVKGGRLSGGQRQRLAIARAMLKDAPIL 506
Query: 498 ILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSP 557
ILDEA +++D ++E+LVQ+A+ +LM RT+++IAHRLS + AD+V+V+D GRI+E G+
Sbjct: 507 ILDEATAALDNESERLVQDALQRLMPERTTLVIAHRLSTIKHADQVLVMDQGRIIESGTH 566
Query: 558 GELLSRKGYFYKLYTSQMQEVP 579
+LL+R G + LY+ Q +E P
Sbjct: 567 VDLLARDGLYAYLYSMQFRERP 588
>gi|11419475 ATP-binding cassette, sub-family B, member 8 [Homo sapiens]
Length = 818
Score = 239 bits (603), Expect = 7e-62
Identities = 137/389 (35%), Positives = 221/389 (56%), Gaps = 6/389 (1%)
Query: 197 IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIAS 256
IA+ V +E++ + T+RAF E+ E+ + + + +F L NIA
Sbjct: 410 IARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAF 469
Query: 257 LLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIY 316
V+ + GG L ++ G +++F+ +Q + + N+ ++ + L+A R++
Sbjct: 470 NCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVF 529
Query: 317 EILDDENVEDYEG---ISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIV 371
E + G + E+L+G + F+NV F Y G VLKD L +PP VA+V
Sbjct: 530 EYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALV 589
Query: 372 GKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRI-GYVPQETYLFPGTIM 430
G++G GKTT+A+L+ RFYDPT G ++ DG D + + LR ++ G++ QE LF TIM
Sbjct: 590 GQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIM 649
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
ENI EA +E+V +E H+FI P+GY T GE G LS G++Q +++ARA+
Sbjct: 650 ENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARAL 709
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
+K P ++ILDEA S++D ++E++VQ A+ + GRT ++IAHRLS R A ++V+ DGR
Sbjct: 710 IKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGR 769
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQMQEVP 579
+ E G+ ELL + G + +L Q + P
Sbjct: 770 VWEAGTHEELLKKGGLYAELIRRQALDAP 798
>sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49 (P-GLYCOPROTEIN 49)
>gi|103251|pir||A41249 multidrug resistance protein
homolog Mdr49 - fruit fly (Drosophila melanogaster)
>gi|157871|gb|AAA28679.1| (M59076) P glycoprotein
[Drosophila melanogaster]
Length = 1302
Score = 238 bits (600), Expect = 2e-61
Identities = 159/519 (30%), Positives = 269/519 (51%), Gaps = 23/519 (4%)
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
L+ VA + TL + +R E +L+ ++ ++ T S + S++ D
Sbjct: 123 LVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTED 182
Query: 129 TNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRR 188
+ + + + ++ + I++ IV+ + KLTLV L+ VP +I A +++
Sbjct: 183 LDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSCVPF-IIAATSVVARLQG 241
Query: 189 AYRETRQK-IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGI 247
+ E K + ++VVEE +GI T+ AF ++ ++ F K+ + +Y G+
Sbjct: 242 SLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGM 301
Query: 248 FWPLMNIASLLSVIVVIAYGGYL----------AYKGAVSIGVVVAFIQYAQRFRGPINN 297
L + L + + I YG L Y AV + V+ A I AQ +
Sbjct: 302 GNALSWLIIYLCMALAIWYGVTLILDERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPH 361
Query: 298 VVSMYDSLQSALAALERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP- 353
V +++ A AA + ++ I+D + D +G E G I F + F Y RP
Sbjct: 362 V----EAIAVATAAGQTLFNIIDRPSQVDPMDEKGNRPENTAGHIRFEGIRFRYP-ARPD 416
Query: 354 --VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
+LK + + + P VA VG +G GK+T+ L+ RFYDP G + DG D + ++ L
Sbjct: 417 VEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWL 476
Query: 412 RKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
R +IG V QE LF TI ENI P A + D+ + + HDFI +LPKGY+T GE
Sbjct: 477 RSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAANCHDFITRLPKGYDTQVGE 536
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G +S G++Q I++ARA+++ P +++LDEA S++DP +E+ VQ+A+ +G T++++A
Sbjct: 537 KGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELASQGPTTLVVA 596
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
HRLS ADK++ + DG + E+G+ EL+ R+G + +L
Sbjct: 597 HRLSTITNADKIVFLKDGVVAEQGTHEELMERRGLYCEL 635
Score = 234 bits (591), Expect = 2e-60
Identities = 155/511 (30%), Positives = 269/511 (52%), Gaps = 14/511 (2%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLVSRIINDTNVVNDVLVS 138
LQT+ G K+ LR + I+ ++ +F + S G L SR+ +D + V +
Sbjct: 795 LQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGA 854
Query: 139 GLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIA 198
+ L ++ +L +V + + TL+TL ++PL+ + G + ++ ++ + I
Sbjct: 855 RVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIE 914
Query: 199 KISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLL 258
+ S V E++ I T+ E+ V ++ + A R + G+ + L A L
Sbjct: 915 EASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDVACRRKVRFRGLVFALGQAAPFL 974
Query: 259 SVIVVIAYGGYLAYKGAVS----IGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
+ + + YGG L + ++ I V A I + + ++ D++ SA ++
Sbjct: 975 AYGISMYYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDL 1034
Query: 315 IYEILDDENVEDYEGISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVG 372
N +VEK +G+I + NV FEY KG P+L+ +NL I ++ VA+VG
Sbjct: 1035 FKRTSTQPNPPQSPYNTVEKSEGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVG 1094
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMEN 432
+G+GK+T L++R+YDP G + G+ + +LR ++G V QE LF TI EN
Sbjct: 1095 PSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAEN 1154
Query: 433 ILMAN---PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
I N + +++I K+ IH+FI LP+GY+T G+ +L S G++Q I++ARA
Sbjct: 1155 IAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLGKTSQL-SGGQKQRIAIARA 1213
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++++P I+ILDEA S++D ++E++VQ A+ + GRT + IAHRL+ R AD + V+ G
Sbjct: 1214 LVRNPKILILDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRG 1273
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
+VE G+ EL++ + LY MQ+V G
Sbjct: 1274 VVVEHGTHDELMALNKIYANLYL--MQQVSG 1302
>gb|AAF58437.1| (AE003820) Mdr49 gene product [Drosophila melanogaster]
Length = 1279
Score = 238 bits (600), Expect = 2e-61
Identities = 159/519 (30%), Positives = 269/519 (51%), Gaps = 23/519 (4%)
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
L+ VA + TL + +R E +L+ ++ ++ T S + S++ D
Sbjct: 123 LVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTED 182
Query: 129 TNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRR 188
+ + + + ++ + I++ IV+ + KLTLV L+ VP +I A +++
Sbjct: 183 LDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSCVPF-IIAATSVVARLQG 241
Query: 189 AYRETRQK-IAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGI 247
+ E K + ++VVEE +GI T+ AF ++ ++ F K+ + +Y G+
Sbjct: 242 SLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGM 301
Query: 248 FWPLMNIASLLSVIVVIAYGGYL----------AYKGAVSIGVVVAFIQYAQRFRGPINN 297
L + L + + I YG L Y AV + V+ A I AQ +
Sbjct: 302 GNALSWLIIYLCMALAIWYGVTLILDERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPH 361
Query: 298 VVSMYDSLQSALAALERIYEILD---DENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP- 353
V +++ A AA + ++ I+D + D +G E G I F + F Y RP
Sbjct: 362 V----EAIAVATAAGQTLFNIIDRPSQVDPMDEKGNRPENTAGHIRFEGIRFRYP-ARPD 416
Query: 354 --VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSL 411
+LK + + + P VA VG +G GK+T+ L+ RFYDP G + DG D + ++ L
Sbjct: 417 VEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWL 476
Query: 412 RKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGE 471
R +IG V QE LF TI ENI P A + D+ + + HDFI +LPKGY+T GE
Sbjct: 477 RSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAANCHDFITRLPKGYDTQVGE 536
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIA 531
G +S G++Q I++ARA+++ P +++LDEA S++DP +E+ VQ+A+ +G T++++A
Sbjct: 537 KGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELASQGPTTLVVA 596
Query: 532 HRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
HRLS ADK++ + DG + E+G+ EL+ R+G + +L
Sbjct: 597 HRLSTITNADKIVFLKDGVVAEQGTHEELMERRGLYCEL 635
Score = 234 bits (590), Expect = 2e-60
Identities = 155/511 (30%), Positives = 269/511 (52%), Gaps = 14/511 (2%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLVSRIINDTNVVNDVLVS 138
LQT+ G K+ LR + I+ ++ +F + S G L SR+ +D + V +
Sbjct: 772 LQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGA 831
Query: 139 GLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIA 198
+ L ++ +L +V + + TL+TL ++PL+ + G + ++ ++ + I
Sbjct: 832 RVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIE 891
Query: 199 KISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLL 258
+ S V E++ I T+ E+ V ++ + A R + G+ + L A L
Sbjct: 892 EASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFRGLVFALGQAAPFL 951
Query: 259 SVIVVIAYGGYLAYKGAVS----IGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALER 314
+ + + YGG L + ++ I V A I + + ++ D++ SA ++
Sbjct: 952 AYGISMYYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDL 1011
Query: 315 IYEILDDENVEDYEGISVEKLKGEIEFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVG 372
N +VEK +G+I + NV FEY KG P+L+ +NL I ++ VA+VG
Sbjct: 1012 FKRTSTQPNPPQSPYNTVEKSEGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVG 1071
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMEN 432
+G+GK+T L++R+YDP G + G+ + +LR ++G V QE LF TI EN
Sbjct: 1072 PSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAEN 1131
Query: 433 ILMAN---PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
I N + +++I K+ IH+FI LP+GY+T G+ +L S G++Q I++ARA
Sbjct: 1132 IAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLGKTSQL-SGGQKQRIAIARA 1190
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++++P I+ILDEA S++D ++E++VQ A+ + GRT + IAHRL+ R AD + V+ G
Sbjct: 1191 LVRNPKILILDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRG 1250
Query: 550 RIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
+VE G+ EL++ + LY MQ+V G
Sbjct: 1251 VVVEHGTHDELMALNKIYANLYL--MQQVSG 1279
>pir||S74455 ABC-type transport protein slr1488 - Synechocystis sp. (strain PCC
6803) >gi|1651679|dbj|BAA16607.1| (D90899) ABC
transporter [Synechocystis sp.]
Length = 605
Score = 237 bits (599), Expect = 2e-61
Identities = 164/585 (28%), Positives = 283/585 (48%), Gaps = 38/585 (6%)
Query: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE 60
++ +S+ +L ++ + LAI ++ GS + + +P ILR ID + G
Sbjct: 3 LSPQSNRQVLMAYLSPQWGQVLALAI---ALGGSIILQVLNPQILRYFIDTAMAGGPQTI 59
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
L ++A+ ++ V + + T+ +E NLR L L +L F K G+
Sbjct: 60 LVWLALGFMAIAVVRQGLEIVATYCSETVAWTATNNLRLNLARHTLNLDLTFHKNHCPGE 119
Query: 121 LVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLL----LDVKLTLVTLTSVPLMV 176
LV RI D + + +L LG+ L + G++V + + LTL L ++ ++
Sbjct: 120 LVERIDGDVDALARFFSQFVLQVLGNGLLVVGVLVVLWFEQWQAGLGLTLFALVALGILS 179
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
+ G + YR A + E +AG+E IR G V F + ++
Sbjct: 180 RLQSLAVGPWQ-VYRGIS---ADFYGFITEYLAGLEDIRGNGAVDYVMNRFYTLIRNWLR 235
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
A+ + + + W + + +A G YL ++IG V YA + PI
Sbjct: 236 AFHQARLQSTLLWGSTVGLFTVGNAIALALGAYLWRVQGITIGTVYLLFYYASLLQDPIE 295
Query: 297 NVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGE--IEFRNVWFEY------ 348
+ + Q A+A+L RI +++ ++ G S G +E +NVWF Y
Sbjct: 296 RIREELEQFQQAVASLYRIQDLIR-QSPSPRLGRSQALPSGSLSVEGKNVWFSYPTTASL 354
Query: 349 ------------------EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYD 390
E L+++ ++P + ++G TG+GK+T A L++ FY
Sbjct: 355 KPGDGNHELPEHRQGHHHEDADYALQNLTWHLPAGKVLGLLGHTGSGKSTFARLLLNFYA 414
Query: 391 PTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCK 450
+G+I GI+ +IS++ L +R+G+V Q+ LF +I N+ NP + +++
Sbjct: 415 IQQGQIQLGGINLGEISQRELHQRVGFVTQDVQLFQTSIRNNLTFFNPHIPDRLILQALN 474
Query: 451 ELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKT 510
+LG+ ++ LP+G +T G G LS G+ QL++ AR LKDP +VILDEA S +DP T
Sbjct: 475 DLGLEPWLATLPQGLDTELGTDGGGLSAGQAQLLAFARVFLKDPGLVILDEASSRLDPLT 534
Query: 511 EQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEG 555
EQL++ A+ +L+E RT IIIAHRL AD+++++D G+++E G
Sbjct: 535 EQLIERAINRLLEHRTGIIIAHRLKTVERADQILILDRGKVLEYG 579
>pir||G71731 mitochondrial transporter atm1 precursor (atm1) RP205 - Rickettsia
prowazekii >gi|3860769|emb|CAA14670.1| (AJ235270)
MITOCHONDRIAL TRANSPORTER ATM1 PRECURSOR (atm1)
[Rickettsia prowazekii]
Length = 609
Score = 237 bits (599), Expect = 2e-61
Identities = 162/561 (28%), Positives = 285/561 (49%), Gaps = 14/561 (2%)
Query: 27 VVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLL------SLVAQWFFTT 80
+V S++ +A + + ++ + YII G + L ++ ++ ++AQ F
Sbjct: 38 IVTSLICLVIAKVINIFV--PIVYKYIIDGLNQNLSLSVLIGVIIGYGGTKILAQIFSEL 95
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
+++V G + R + + + + ++ F T+ TG L I T + VL L
Sbjct: 96 RNIIFSKV-GCQATRLVALNVFKHMHNLSMRFHITRKTGGLSRSIERGTKGIEAVLRYSL 154
Query: 141 LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAY-RETRQKIAK 199
+ L + +I + VTL ++ + R ++ RE Q
Sbjct: 155 FNIFPTSLEIILVIGILWYFHGIWFAVTLLITMIVYVCYTLLISTWRISFAREMNQSDNT 214
Query: 200 ISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLS 259
++ +S+ ET++ F E+ +F+ K+ ++ + I ++ L
Sbjct: 215 ANNRAIDSLLNFETVKYFNNEEYEAIKFNDALQAYEKSATKITNSLSILNIGQDVIISLG 274
Query: 260 VIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEIL 319
++ ++ + + +G ++ Y + P++ + Y +++AL +E ++++L
Sbjct: 275 LVSLMILSVNAINQNKMMVGDLIMVNAYLFQLSIPLSILGFAYREIKNALVNMEDMFKLL 334
Query: 320 DDENVEDYEGISVEKL---KGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGA 376
D E + + ++L K ++ F NV F Y K R +L ++ I +A+VG +GA
Sbjct: 335 DIP-AEIQDSVDAKELIISKCKVSFNNVSFAYNKERTILHNITFTIESGKTIAVVGSSGA 393
Query: 377 GKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMA 436
GK+TI+ L+ RFYD G I+ D D +++ + SLRK IG VPQ+T LF TI NI
Sbjct: 394 GKSTISRLLFRFYDINSGSIIIDNQDIREVKQGSLRKSIGIVPQDTVLFNDTIYYNIAYG 453
Query: 437 NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDI 496
N A ++VI K IH+FI LP+GY T GE G LS GE+Q I++AR +LK+P I
Sbjct: 454 NNAASYDEVIAASKNAHIHEFISVLPEGYATQVGERGLKLSGGEKQRIAIARTILKNPSI 513
Query: 497 VILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGS 556
+ DEA SS+D KTE+L+Q ++ ++ T++IIAHRLS AD++IV+D+G IVE G+
Sbjct: 514 YVFDEATSSLDTKTEKLIQASLKEISANHTTLIIAHRLSTIVDADEIIVLDNGYIVERGN 573
Query: 557 PGELLSRKGYFYKLYTSQMQE 577
LL +GY+ +L+ Q +E
Sbjct: 574 HKTLLKNQGYYAELWYKQQEE 594
>dbj|BAA34383.1| (AB019513) ABC transporter [Streptomyces coelicolor A3(2)]
Length = 584
Score = 237 bits (599), Expect = 2e-61
Identities = 165/558 (29%), Positives = 269/558 (47%), Gaps = 10/558 (1%)
Query: 28 VVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTE 87
++S+V A L P + R ID + R +AM L+ VA L ++
Sbjct: 32 LLSLVTGA-TGLLLPLVARELIDD-LAQDRAITGALLAMSGLV--VANTALGALGSYVLR 87
Query: 88 VFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLG-GLGS 146
+ V+ R L +L+ + GDL++RI +DT ++ +V L+G G G
Sbjct: 88 RTAESVVLGARRTLSSYLLRLRIAAVDRTEPGDLMARITSDTTLLREVTTDSLIGLGTGG 147
Query: 147 ILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEE 206
L+L +V M ++D L VTL V + ++ RA R+ + + + + +E
Sbjct: 148 -LTLVATLVMMGVVDPVLLGVTLAVVLGAGTVLGLIVPRINRASRQAQDAVGVMGAALER 206
Query: 207 SVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAY 266
+ + T++A G E E+ + + E+ + +R A + +A ++ I V+A
Sbjct: 207 ILGALRTVKASGAEPREERVLHEAAEESWRQSVRAAKWSAAAGNTAGLAMQIAFITVLAV 266
Query: 267 GGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILD---DEN 323
GG GA+ +G +VAF+ + PI VV Q+ AAL RI + L +
Sbjct: 267 GGARVATGAIDVGTLVAFLLFVFYLMSPIQQVVGAITQYQTGRAALGRIQDALGLPAEPQ 326
Query: 324 VEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKD-VNLYIPPASKVAIVGKTGAGKTTIA 382
S + FR V F Y P + V+ +P A VG +GAGKTT+
Sbjct: 327 ARPVPLPSAGAPPASVSFREVRFRYADDLPYIHHGVSFEVPARGMTAFVGPSGAGKTTVF 386
Query: 383 NLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKE 442
+L+ RFYDP GEI DG SLR IGYV Q+ + G++ +N+L+ NPE E
Sbjct: 387 SLVERFYDPDSGEITLDGRSLGDWELSSLRASIGYVEQDAPVLSGSLRDNLLLGNPEGDE 446
Query: 443 EDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEA 502
+ V K + + +LP G ET G G LS GERQ +++ARA+L+ P +++LDEA
Sbjct: 447 ATLAAVLKTTRLDGLVERLPNGLETLVGHRGTKLSGGERQRVAIARALLRRPRLLLLDEA 506
Query: 503 LSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLS 562
S +D E +++ + + T +++AHRLS AD+++V+D GR+ G+ EL++
Sbjct: 507 TSQLDAVNEAALRDTVADVARTTTVLVVAHRLSTVTMADRIVVMDAGRVRAVGTHRELVT 566
Query: 563 RKGYFYKLYTSQMQEVPG 580
+ +L +Q G
Sbjct: 567 ADPLYAELAATQFLATGG 584
>pir||F82939 transport ATP-binding protein UU060 [imported] - Ureaplasma
urealyticum >gi|6899009|gb|AAF30465.1|AE002105_6
(AE002105) transport ATP-binding protein [Ureaplasma
urealyticum]
Length = 598
Score = 237 bits (599), Expect = 2e-61
Identities = 157/575 (27%), Positives = 289/575 (49%), Gaps = 35/575 (6%)
Query: 29 VSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFFTTLQTFYTEV 88
++I+ +A+ ++L+ +D Y I + + L+ +FF+ +
Sbjct: 33 IAIIFWLSTTIAATFLLQETVDKYAIANGIVDT---VVKMCAGLIGIYFFSFIFLLIINE 89
Query: 89 FGQKVLRNLRSQLHEKILQS----NLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGL 144
F ++ + S L ++ + +F +G++ ++ ++D V D +V+ +
Sbjct: 90 FAIRISFKIESHLSMMVINRIRYLPMKYFDINKSGEIFTKTLSDPTSVQDGIVNFYIELN 149
Query: 145 GSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVV 204
+I G A+L+ + L+ + L+++ + K + R RQ +++ +
Sbjct: 150 KAIFGAIGFGTALLITSPYIALIGIVIYVLVMLFNILIFKKSHQLMRIKRQNFGEMNGYI 209
Query: 205 EESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWP-------LMNIASL 257
EE + G + F ++ K+ + + K +++ I +P LMN +
Sbjct: 210 EEMIYGQNVVANFNEQVFFIKKLDNMIKKLYKNWIKAQYSSQIIFPWSIFSMRLMNAVLI 269
Query: 258 LSVIVVIAYGGYL--------------AYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
+S +++ G +L ++ G VSI + F + F ++N + ++
Sbjct: 270 VSYLLISIKGIHLPGLINNIDPTTNIISFGGLVSISLFGNF--FCDNF-SQLSNTIPIFI 326
Query: 304 SLQSALAALERIYEILDDENVEDYEGISVEKLKG-EIEFRNVWFEYEKGRPVLKDVNLYI 362
+++LA ++ I + ++ N E + ++ +G E+ F NV F Y K P LK++N
Sbjct: 327 VARTSLAKIDEIVKTPNEINWN--EKLIIDASQGIEVRFENVNFNYLKNTPTLKNINFVA 384
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
++AI+G TGAGKTTI NLI +FYD G I ++ +D SR+S+R+ I V Q+
Sbjct: 385 KRNQRIAIIGPTGAGKTTITNLINKFYDINNGFIYFNDVDITNKSRESVREHISIVLQDP 444
Query: 423 YLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
+LF +I ENI A +E++I K+ +HD I+ PK Y T E + LS G++Q
Sbjct: 445 FLFSESIYENIKKGKMNATKEEIIAAAKKAQVHDLILSFPKDYATVIDEK-QNLSQGQKQ 503
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
LI++ARA++ D I+ILDEA SSVD +TE +Q A+ L++GRTS IIAHRLS +D
Sbjct: 504 LITIARAIISDAKIIILDEATSSVDTQTEHKLQLAINNLLKGRTSFIIAHRLSTIINSDL 563
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
++V+ DG I+ +G+ L+ ++ +LY + E
Sbjct: 564 ILVIKDGEIIAQGNHDYLIKNSPFYQELYYANFNE 598
>gb|AAF65552.1|AF249879_1 (AF249879) liver bile salt export pump [Oryctolagus cuniculus]
Length = 1321
Score = 237 bits (599), Expect = 2e-61
Identities = 158/563 (28%), Positives = 279/563 (49%), Gaps = 17/563 (3%)
Query: 27 VVVSIVGSALANLASP---YILRVAIDHYIIPGRYKE---LGFIAMLYLLSLVAQWFFTT 80
+++ +G+A+ +P ++ + + +P + ++ + I +L++ +F
Sbjct: 755 MLLGSMGAAVNGAVTPLYAFLFSQILGTFSLPDKEEQRSQINGICLLFVTLGCVSFFTQF 814
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTGDLVSRIINDTNVVNDVLVS 138
LQ + G+ + + LR +L ++ +F S G L +R+ D + V S
Sbjct: 815 LQGYTFAKSGELLTKRLRKFGFRAMLGQDIGWFDDLRNSPGALTTRLATDASQVQGATGS 874
Query: 139 GLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIA 198
+ + S ++ ++ L KLTL + P + + + +Q +
Sbjct: 875 QIGMMVNSFTNVTVAMIIAFLFSWKLTLGIVCFFPFLALSGALQTKMLTGFASRDKQALE 934
Query: 199 KISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLL 258
K + E+++ I T+ GKE+ + F + K ++ A G+ + + +
Sbjct: 935 KAGQITSEALSNIRTVAGIGKERKFIETFEAELEKPYKMAIKKANVYGLCFGFSQCITFI 994
Query: 259 SVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEI 318
+ YGGYL + V I + S S A + R +++
Sbjct: 995 ANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRASSYTPSYAKAKISAARFFQL 1054
Query: 319 LDDE---NVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVG 372
LD + NV G + +G+I+F + F Y RP VL +++ + P +A VG
Sbjct: 1055 LDRQPPINVYSSAGEKWDNFQGKIDFVDCKFTYPS-RPDIQVLNGLSVSMSPRQTLAFVG 1113
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMEN 432
+G GK+T L+ RFYDP G+++ DG D +K++ + LR IG V QE LF +I +N
Sbjct: 1114 SSGCGKSTSIQLLERFYDPDHGKVMIDGHDSRKVNIQFLRSNIGIVSQEPVLFACSIKDN 1173
Query: 433 ILMAN--PEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
I + E E +I K+ +HDF+M LP+ YET+ G G LS GE+Q I++ARA+
Sbjct: 1174 IKYGDNTQEIPMERIIAAAKKAQVHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAI 1233
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
++DP I++LDEA S++D ++E+ VQ A+ K EGRT I+IAHRLS + +D + V+ G
Sbjct: 1234 VRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGM 1293
Query: 551 IVEEGSPGELLSRKGYFYKLYTS 573
++E+G+ EL+ +KG +YKL T+
Sbjct: 1294 VIEKGTHEELMVQKGAYYKLVTT 1316
Score = 236 bits (595), Expect = 6e-61
Identities = 161/497 (32%), Positives = 254/497 (50%), Gaps = 14/497 (2%)
Query: 94 LRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILS-LAG 152
++ +R KI++ + + S G L + D N +ND L + + S + G
Sbjct: 171 IQKMRKSYFRKIMRMGIGWVDCNSVGKLNTPFSVDFNKINDSSADQLAIFIQGMTSPIFG 230
Query: 153 IIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIE 212
+V KLTLV ++ PL+ + A G + + + AK SV +E ++ +
Sbjct: 231 FLVGFSQW-WKLTLVIISVSPLIGLGAAIIGLSVSKFTDYELKAYAKAGSVADEVISSMR 289
Query: 213 TIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAY 272
T+ AFG EK + + K + +R I MG F M + YG L
Sbjct: 290 TVAAFGGEKKEVERYEKNLVFAQRWGIRKGIVMGFFTGYMWCLIFFCYALAFWYGSKLVL 349
Query: 273 K-GAVSIGVVVAFIQYAQRFRGPIN--NVVSMYDSLQSALAALERIYEILDDENVEDY-- 327
+ G S G +V + G +N N ++ + AA I+E +D + + D
Sbjct: 350 EEGEYSPGALVQI--FLSVIIGALNLGNASPCLEAFAAGRAAASSIFETIDRKPIIDCMS 407
Query: 328 -EGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
+G +E++KGEIEF NV F Y RP +L ++++ I P A+VG +GAGK+T
Sbjct: 408 EDGYKLERIKGEIEFHNVTFHYPS-RPEVKILNNLSMVIKPGEMTALVGPSGAGKSTALQ 466
Query: 384 LIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEE 443
LI RFY PT+G + + D + + LR +IG V QE LF TI E I +A E
Sbjct: 467 LIHRFYGPTEGMVTVESHDIRSSHIQWLRNQIGIVEQEPVLFFHTIAEKIRYGREDATME 526
Query: 444 DVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEAL 503
D+I+ KE ++FIM LP+ ++T GE G +S G++Q +++ARA++++P I++LD A
Sbjct: 527 DLIQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMAT 586
Query: 504 SSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSR 563
S++D ++E +VQ A+ K G T + +AHR + R AD +I + G VE G+ ELL R
Sbjct: 587 SALDNESEAMVQEALSKTQHGHTIVSVAHRPATIRTADVIIGCEHGAAVERGTEEELLER 646
Query: 564 KGYFYKLYTSQMQEVPG 580
KG ++ L T Q Q G
Sbjct: 647 KGVYFALVTLQSQRNQG 663
>gb|AAA16186.1| (L07065) P-glycoprotein/multidrug resistance protein [Drosophila
melanogaster]
Length = 1283
Score = 236 bits (595), Expect = 6e-61
Identities = 151/519 (29%), Positives = 262/519 (50%), Gaps = 9/519 (1%)
Query: 65 AMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLV 122
++ +L++ + T LQ ++ + G+++ LR + E +L+ + +F K TG L
Sbjct: 761 SLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGTGSLC 820
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+R+ D V + + SI +LA I + + L LV L P ++I
Sbjct: 821 ARLSGDAAAVQGATGQRIGTIIQSISTLALGIALSMYYEWSLGLVALAFTPFILIAFYMQ 880
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
M + + + + + E V+ I T+ + G+E+ + + + ++ R
Sbjct: 881 RTLMAKENMRPAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEISKRNT 940
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
+ G+ + L + + YG + + G V Q I N ++
Sbjct: 941 HFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQAVIMGTASIANALAFA 1000
Query: 303 DSLQSALAALERIYEILDDE-NVEDYEGISVEKL--KGEIEFRNVWFEYEKGRP--VLKD 357
++Q ++A + I+ L + ++ D G+S + +G + F V F Y VLK
Sbjct: 1001 PNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPWHSEGYVRFDKVKFSYPTRSEIQVLKG 1060
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
+ L + K+A+VG +G GK+T LI RFYD +G L D D + +S +LR ++G
Sbjct: 1061 LELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRNQLGI 1120
Query: 418 VPQETYLFPGTIMENILMANP--EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKL 475
V QE LF TI ENI + ++++I CK+ IH+FI LP GY+T GE G
Sbjct: 1121 VSQEPILFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGEKGAQ 1180
Query: 476 LSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLS 535
LS G++Q I++ARA++++P I++LDEA S++D ++E++VQ+A+ EGRT+I IAHRLS
Sbjct: 1181 LSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAASEGRTTISIAHRLS 1240
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+D + V ++G + E G +LL+ +G +Y LY Q
Sbjct: 1241 TVVHSDVIFVFENGLVCEAGDHKQLLANRGLYYTLYKLQ 1279
Score = 228 bits (576), Expect = 1e-58
Identities = 158/509 (31%), Positives = 260/509 (51%), Gaps = 41/509 (8%)
Query: 97 LRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVA 156
+RS+ IL ++ ++ +G++ SR+ D + + D L ++ + +++ G +V
Sbjct: 152 IRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVL 211
Query: 157 MLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRA 216
+ +L+LV LTS+PL I R ++ A + V E +++GI T++A
Sbjct: 212 AFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKA 271
Query: 217 F-GKEKDVEKEFSKVSTE---TIKAYLRVAIYMGIFWPLMNIASL-------LSVIVVIA 265
F G+ K+V +V IK + I G+ W AS + +++ A
Sbjct: 272 FEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFFIYASYALAFWYGVGLVIESA 331
Query: 266 YGGYLA----------YKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERI 315
Y Y A G+++IG+ +I+ +G + V + + + + R+
Sbjct: 332 YENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAQGRLPKVFHIIEQIPEINPLMGRV 391
Query: 316 YEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVG 372
V + IEF+ V F+Y RP +L +NL I VA+VG
Sbjct: 392 ---------------KVNEPLTTIEFKEVEFQYPT-RPEVSILNKLNLKIHRGQTVALVG 435
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR-KRIGYVPQETYLFPGTIME 431
+G GK+T L+ RFYDP G +L++G + K + LR RIG V QE LF +I E
Sbjct: 436 PSGCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRFLRIGVVGQEPILFATSIYE 495
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI +A E++ FI KLPKGY+T GE G LS G++Q I++ RA++
Sbjct: 496 NIRYGREDATREEIEAARAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIRRALI 555
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
+DP+I++LDEA S++D +E VQ A+ K+ GRT+II+AHRLS R AD+++V++ G +
Sbjct: 556 RDPEILLLDEATSALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEV 615
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
VE G+ EL+ K +++ L T+Q+ E G
Sbjct: 616 VESGTHQELMELKDHYFNLVTTQLGEDDG 644
>pir||A47377 multidrug resistance protein Mdr50 - fruit fly (Drosophila
melanogaster)
Length = 1283
Score = 236 bits (595), Expect = 6e-61
Identities = 151/519 (29%), Positives = 262/519 (50%), Gaps = 9/519 (1%)
Query: 65 AMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFF--KTKSTGDLV 122
++ +L++ + T LQ ++ + G+++ LR + E +L+ + +F K TG L
Sbjct: 761 SLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGTGSLC 820
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+R+ D V + + SI +LA I + + L LV L P ++I
Sbjct: 821 ARLSGDAAAVQGATGQRIGTIIQSISTLALGIALSMYYEWSLGLVALAFTPFILIAFYMQ 880
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVA 242
M + + + + + E V+ I T+ + G+E+ + + + ++ R
Sbjct: 881 RTLMAKENMRPAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEISKRNT 940
Query: 243 IYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
+ G+ + L + + YG + + G V Q I N ++
Sbjct: 941 HFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQAVIMGTASIANALAFA 1000
Query: 303 DSLQSALAALERIYEILDDE-NVEDYEGISVEKL--KGEIEFRNVWFEYEKGRP--VLKD 357
++Q ++A + I+ L + ++ D G+S + +G + F V F Y VLK
Sbjct: 1001 PNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPWHSEGYVRFDKVKFSYPTRSEIQVLKG 1060
Query: 358 VNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGY 417
+ L + K+A+VG +G GK+T LI RFYD +G L D D + +S +LR ++G
Sbjct: 1061 LELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRNQLGI 1120
Query: 418 VPQETYLFPGTIMENILMANP--EAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKL 475
V QE LF TI ENI + ++++I CK+ IH+FI LP GY+T GE G
Sbjct: 1121 VSQEPILFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGEKGAQ 1180
Query: 476 LSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLS 535
LS G++Q I++ARA++++P I++LDEA S++D ++E++VQ+A+ EGRT+I IAHRLS
Sbjct: 1181 LSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAASEGRTTISIAHRLS 1240
Query: 536 ITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+D + V ++G + E G +LL+ +G +Y LY Q
Sbjct: 1241 TVVHSDVIFVFENGLVCEAGDHKQLLANRGLYYTLYKLQ 1279
Score = 228 bits (576), Expect = 1e-58
Identities = 158/509 (31%), Positives = 260/509 (51%), Gaps = 41/509 (8%)
Query: 97 LRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVA 156
+RS+ IL ++ ++ +G++ SR+ D + + D L ++ + +++ G +V
Sbjct: 152 IRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVL 211
Query: 157 MLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRA 216
+ +L+LV LTS+PL I R ++ A + V E +++GI T++A
Sbjct: 212 AFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKA 271
Query: 217 F-GKEKDVEKEFSKVSTE---TIKAYLRVAIYMGIFWPLMNIASL-------LSVIVVIA 265
F G+ K+V +V IK + I G+ W AS + +++ A
Sbjct: 272 FEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFFIYASYALAFWYGVGLVIESA 331
Query: 266 YGGYLA----------YKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERI 315
Y Y A G+++IG+ +I+ +G + V + + + + R+
Sbjct: 332 YENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAQGRLPKVFHIIEQIPEINPLMGRV 391
Query: 316 YEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPPASKVAIVG 372
V + IEF+ V F+Y RP +L +NL I VA+VG
Sbjct: 392 ---------------KVNEPLTTIEFKEVEFQYPT-RPEVSILNKLNLKIHRGQTVALVG 435
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR-KRIGYVPQETYLFPGTIME 431
+G GK+T L+ RFYDP G +L++G + K + LR RIG V QE LF +I E
Sbjct: 436 PSGCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRFLRIGVVGQEPILFATSIYE 495
Query: 432 NILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAML 491
NI +A E++ FI KLPKGY+T GE G LS G++Q I++ RA++
Sbjct: 496 NIRYGREDATREEIEAARAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIRRALI 555
Query: 492 KDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRI 551
+DP+I++LDEA S++D +E VQ A+ K+ GRT+II+AHRLS R AD+++V++ G +
Sbjct: 556 RDPEILLLDEATSALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEV 615
Query: 552 VEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
VE G+ EL+ K +++ L T+Q+ E G
Sbjct: 616 VESGTHQELMELKDHYFNLVTTQLGEDDG 644
>emb|CAB88932.1| (AL353863) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 593
Score = 236 bits (595), Expect = 6e-61
Identities = 156/571 (27%), Positives = 286/571 (49%), Gaps = 15/571 (2%)
Query: 10 LKRFIKEALSERRTLAIVVVSI-VGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
++ ++ E L R + +V++ + +A++A PY+L ++ R LG A L+
Sbjct: 28 VRAYVGELLRRHRRAFLFLVTVNTVAVIASMAGPYLLGGLVERVSDDARELRLGLTATLF 87
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
+L+LV Q F V G+++L +LR + + + TGDL+SRI D
Sbjct: 88 VLALVVQAVFVREVRLRGAVLGERMLADLREDFLVRSVGLPPGVLERAGTGDLLSRITTD 147
Query: 129 ----TNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGG 184
N + + + +G + +L L G++V L L +VPL+VI ++
Sbjct: 148 IDRLANAMREAVPQLAIGAVWVVLLLGGLVVTA----PPLAPAVLIAVPLLVIGCRWYFR 203
Query: 185 KMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEK-EFSKVSTETIKAYLRVAI 243
+ AYR A +++ + E+V T+ + D + E S+ A+ R +
Sbjct: 204 RAPAAYRSEAAGYAAVAAALAETVDAGRTVESH--RLDARRIELSERRIREWTAWERYTL 261
Query: 244 YM-GIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMY 302
++ + +P++N+ + + V+ GG +G + +G + AQ P+ ++ Y
Sbjct: 262 WLRSVLFPVINVTHVTVLASVLLIGGVFVLQGWIGVGQLTTAALIAQMLVDPVGIILRWY 321
Query: 303 DSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYI 362
D LQ A +L R+ + D E D ++ + V F Y +G VL+ V+L +
Sbjct: 322 DELQVAQVSLARLVGVRDIE--PDAGDATLAPDGRRVHADRVHFGYLEGVDVLRKVSLEV 379
Query: 363 PPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQET 422
P +++A+VG +GAGK+T+ L+ Y P +G I G + ++S + +R + V QE
Sbjct: 380 APGTRLALVGPSGAGKSTLGRLLAGIYGPREGRITLGGAELSRMSAERVRSHVALVNQEH 439
Query: 423 YLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQ 482
++F G++ +N+ +A A + ++ + D+ L +G +T G G L+ + Q
Sbjct: 440 HVFVGSLRDNLRLARTSATDAELWAALGAVDADDWSRGLDEGLDTEVGSGGFALTPAQAQ 499
Query: 483 LISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
I+LAR +L DP ++LDEA S +DP+ + ++ ++ ++++GRT I IAHRL AD
Sbjct: 500 QIALARLVLADPHTLVLDEATSLLDPRAARHLERSLARVLDGRTVIAIAHRLHTAHDADV 559
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKLYTS 573
+ VV++GRI E GS EL++ G + L+ S
Sbjct: 560 IAVVENGRISELGSHDELVAADGAYAALWRS 590
>emb|CAB69751.1| (AL137187) putative ABC transporter [Streptomyces coelicolor A3(2)]
Length = 577
Score = 233 bits (587), Expect = 6e-60
Identities = 152/565 (26%), Positives = 289/565 (50%), Gaps = 13/565 (2%)
Query: 21 RRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFI----AMLYLLSLVAQW 76
++ +A++V A+L P + ID ++ G + G+I A++ +SL AQ
Sbjct: 14 KKPIALLVALQFLQTCASLYLPTLNAHIIDEGVVKG---DSGYILSYGALMIGISL-AQV 69
Query: 77 FFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDV- 135
FY + R++R + +++ + L++R ND V +
Sbjct: 70 VCNIGAVFYGARTAAALGRDVRGAVFDRVQSFSAREVGHFGAPSLITRTTNDVQQVQMLA 129
Query: 136 LVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQ 195
L++ L I+ + GI++A L LDV L+ V L VP++ I K+R +R+ +
Sbjct: 130 LMTFTLMVSAPIMCVGGIVMA-LGLDVPLSGVLLGVVPVLAICVTLIVRKLRPLFRKMQV 188
Query: 196 KIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIA 255
++ ++ V+ E + G IRAF +++ ++ F K +TE + L + + +P++
Sbjct: 189 RLDTVNRVLREQITGNRVIRAFVRDEYEQQRFRKANTELTEVALGTGNLLALMFPVVMTV 248
Query: 256 SLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERI 315
LS I V+ +G + G + IG + AF+ Y + + M+ + A ERI
Sbjct: 249 VNLSSIAVVWFGAHRIDSGGMQIGDLTAFLAYLMQIVMSVMMATFMFMMVPRAEVCAERI 308
Query: 316 YEILDDEN--VEDYEGISVEKLKGEIEFRNVWFEYEKGR-PVLKDVNLYIPPASKVAIVG 372
E+L+ E+ V ++ + G +E R F Y PVL+ ++L P A++G
Sbjct: 309 QEVLETESSVVPPVAPVTELRRHGHLEIREAGFRYPGAEEPVLRHIDLVARPGETTAVIG 368
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMEN 432
TG+GK+T+ L+ R +D T GE+L +G+D + + K+L K + VPQ+ YLF GT+ N
Sbjct: 369 STGSGKSTLLGLVPRLFDATDGEVLVNGVDVRTVDPKTLAKVVSLVPQKPYLFAGTVATN 428
Query: 433 ILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLK 492
+ NP+A +E++ +F+ +L G + + G +S G+RQ +++AR +++
Sbjct: 429 LRYGNPDATDEELWHALAVAQAKEFVSELEGGLDAPIAQGGTNVSGGQRQRLAIARTLVQ 488
Query: 493 DPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIV 552
P+I + D++ S++D T+ ++ + + T +I+A R++ R AD+++V+D+GR+V
Sbjct: 489 RPEIYLFDDSFSALDYATDAALRAELAQETAEATVVIVAQRVATIRDADRIVVLDEGRVV 548
Query: 553 EEGSPGELLSRKGYFYKLYTSQMQE 577
G EL++ + ++ SQ+ E
Sbjct: 549 GVGRHHELMADNETYREIVLSQLTE 573
>gb|AAD49436.1|AF083642_1 (AF083642) P-glycoprotein [Onchocerca volvulus]
Length = 1278
Score = 231 bits (582), Expect = 2e-59
Identities = 153/509 (30%), Positives = 259/509 (50%), Gaps = 13/509 (2%)
Query: 79 TTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVL-- 136
TT+Q + + +R + + +L+ +F + TG L +++ + + D +
Sbjct: 125 TTIQYICAKNASLNITCTMRQEYMKSLLRQEAAWFDQQKTGTLTAQLNANIEKIKDGIGD 184
Query: 137 -VSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQ 195
V +L G+ L+ ++ + D +LTLV + P+ + +M +
Sbjct: 185 KVGMILRGVTMFLTC---VIIGFIYDWRLTLVMFGTGPISAALLSTMARQMEHSSSMQSN 241
Query: 196 KIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIA 255
+ ++V+EES+ ++T+ A ++ + K ++ K L + G F L +
Sbjct: 242 TDGRAAAVLEESIMNVKTVAACNAQETMIKRYAATLKACRKFALHAYAFAGFFDGLFFLV 301
Query: 256 SLLSVIVVIAYGGYLAYKGAVS----IGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAA 311
+ YG YL + I V I + G ++ + + + A A
Sbjct: 302 LYVFFAAGFYYGAYLYQIRIIMNPGYIFAVANLIMFGSYNLGVLSPHLMAVLNARVAAAV 361
Query: 312 LERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP--VLKDVNLYIPPASKVA 369
+ +I + +G+ V ++KGEIEF+NV F Y K + VL ++ P VA
Sbjct: 362 IYKIINRKPSFDSSSTDGMKVNEVKGEIEFQNVKFSYPKSKEHLVLNGLSWTAKPGDTVA 421
Query: 370 IVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTI 429
+VG +G GK+T L+ R Y+ G IL DGI+ I+ +LR +G V QE LF GTI
Sbjct: 422 LVGHSGCGKSTSTGLLTRLYNCNSGAILIDGINICDINIHTLRNIVGVVQQEPLLFSGTI 481
Query: 430 MENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARA 489
ENI + + ++++I CK HDFI KL +GY+T G G LS G++Q I++AR
Sbjct: 482 KENIRLGKLDLTDQEIIDACKIANAHDFINKLSEGYDTMIGAGGIQLSGGQKQRIAIART 541
Query: 490 MLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDG 549
++++P I++LDEA S++D ++E +VQNA+ K GRT+IIIAHRLS R ++++IV+D G
Sbjct: 542 IVRNPRILLLDEATSALDAESEVIVQNALKKAFVGRTTIIIAHRLSTLRDSNQIIVLDKG 601
Query: 550 RIVEEGSPGELLSRK-GYFYKLYTSQMQE 577
++ E G+ EL + K G + L SQ E
Sbjct: 602 QVAEIGTHKELCNNKDGIYASLVKSQQFE 630
Score = 189 bits (475), Expect = 8e-47
Identities = 158/537 (29%), Positives = 251/537 (46%), Gaps = 50/537 (9%)
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV- 122
IA++Y+ +A TF + V+ +LR + +L N ++F T ST V
Sbjct: 762 IAIIYIALGIACLIVIFSATFTFGWTAECVVDSLRLRAMRNMLYQNAEYFDTPSTSTAVT 821
Query: 123 -------------SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTL 169
SR ND N N IVA+L+L V + ++
Sbjct: 822 VTRISVDAQTLKRSRSANDANFDN--------------------IVAILVL-VTIAVIFN 860
Query: 170 TSVPLMVIIA--LYFGGKMRRAYRETRQKIAKISSVVE----ESVAGIETIRAFGKEKDV 223
V L+ + + +F + R Y K A V E V I TI+ E+
Sbjct: 861 WPVGLLAVKSPVTHFDADIDRKYNAEVNKCALKQIVTGQLALEIVEQIRTIQLITGEEHF 920
Query: 224 EKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVA 283
+ + + + + + + Y I + + + S ++ A G L Y G S+ +
Sbjct: 921 HRLYVQTIEDLLYLQKKSSPYEAILFAVTSSFMFFSDMISYAAGIALIYYG-YSLPQEIF 979
Query: 284 FIQYAQRFRG----PINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEI 339
++ G ++ ++ + A +L RI D N D +G+ + G++
Sbjct: 980 TASWSIATSGWALIMVSGCLNTFVMASPASNSLFRIINTGSDMNSVD-DGLR-PAITGDV 1037
Query: 340 EFRNVWFEY--EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEIL 397
+F + F Y R VL +NL VA+ G +G+GK+T+ L+ RFY G++
Sbjct: 1038 QFNKIKFSYPTRPQRNVLNGLNLAAYAGQTVAVTGPSGSGKSTVIALLERFYRFNSGQLT 1097
Query: 398 YDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDF 457
D KIS + LR++I V QE LF GTI+ENIL+ DV CK I DF
Sbjct: 1098 LDDNSITKISLRYLREQIALVGQEPILFSGTILENILLGTTGKTLSDVREACKIANIIDF 1157
Query: 458 IMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNA 517
I PKGY+T GE G LS G++Q I++ARA++++P I++LDEA S++D + E+ VQ A
Sbjct: 1158 IETSPKGYDTEVGEHGVQLSGGQKQRIAIARALVRNPKILLLDEATSALDAECERTVQQA 1217
Query: 518 MIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+ GRT I +AHRLS + AD++ V++G++VEEG+ EL+ G + L Q
Sbjct: 1218 LDAASSGRTCITVAHRLSSIQHADQIFFVENGKVVEEGTHQELVEFDGKYADLIRKQ 1274
>dbj|BAA83673.1| (AB007195) TAP2 [Coturnix japonica]
Length = 698
Score = 231 bits (582), Expect = 2e-59
Identities = 166/568 (29%), Positives = 275/568 (48%), Gaps = 15/568 (2%)
Query: 10 LKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYII-PGRYKELGFIAMLY 68
LKR + A E L+ + + +AL + PY A+D G + ++
Sbjct: 136 LKRLLALAWPEWPLLSCAFLFLALAALGETSVPYFTGRALDVLRQGDGLTTFTAAVGLMC 195
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
L S + F +T + + VLR R QL ++ +L FF+ + +L SR+ D
Sbjct: 196 LASASSSLFAGCRGGLFTFIGYRFVLRT-RDQLFSSLVYRDLAFFQKTTAAELSSRLTTD 254
Query: 129 TNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRR 188
+ + VL + L ++ + G+ ML L +LTL+ L VPL V + + +
Sbjct: 255 VTLASKVLTLNINVMLRTLGQVLGLCAFMLGLSPRLTLLALLEVPLAVAARKVYDSRHQM 314
Query: 189 AYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIF 248
R A V+ES++ IET+R F E++ E+ + + + ++ + IF
Sbjct: 315 LQRAVLDAAANTGKQVQESISSIETVRVFNGEEEEERRYRQALGQDLRLRDQRDTEKAIF 374
Query: 249 WPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSA 308
+ L +V+ G + G ++ G +VAFI Y + + Y L S
Sbjct: 375 LLIRRALQLAVQALVLYCGHQQLHDGTLTAGSLVAFILYQTNAGSCVQALAYCYGDLLSN 434
Query: 309 LAALERIYEILDDENVEDYEGISVE-KLKGEIEFRNVWFEYEKGRP---VLKDVNLYIPP 364
AA ++++ LD E G V KL+G I F V F Y RP VL+DV + P
Sbjct: 435 AAAACKVFDYLDRERAVGTGGTYVPTKLQGHITFHRVSFAYPT-RPEHLVLQDVTFELRP 493
Query: 365 ASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYL 424
A+ G G+GK+T L+ RFY+P GE+L DG+ + L +++ V QE L
Sbjct: 494 GEVTALAGLNGSGKSTCVALLERFYEPKAGEVLLDGVPLQDYEHCYLHRQVALVGQEPVL 553
Query: 425 FPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLI 484
F G+I +NI + +EE++I + G FI L +G+ T GE G LS G++Q I
Sbjct: 554 FSGSIRDNIAYGMEDCEEEEIIAAARAAGALGFISALEQGFGTDVGERGGQLSAGQKQRI 613
Query: 485 SLARAMLKDPDIVILDEALSSV--DPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADK 542
++ARA+++ P ++ILDEA S++ D +Q + RT ++I+H+ + AD+
Sbjct: 614 AIARALVRHPTVLILDEATSALDGDGDLQQWTE------WGDRTVLLISHQPRMLEKADR 667
Query: 543 VIVVDDGRIVEEGSPGELLSRKGYFYKL 570
V+V++ G + E G+P EL +R G + +L
Sbjct: 668 VVVLEHGMVAEMGTPTELRTRGGPYSRL 695
>pir||T26313 hypothetical protein W09D6.6 - Caenorhabditis elegans
>gi|3880598|emb|CAB04947.1| (Z82078) predicted using
Genefinder~contains similarity to Pfam domain: PF00005
(ABC transporter), Score=210.9, E-value=6.1e-60,
N=1~cDNA EST yk4g6.5 comes from this gene~cDNA EST
yk10f3.5 comes from this gene~cDNA EST yk135g3.5 comes
from this gene~cD>
Length = 772
Score = 230 bits (581), Expect = 3e-59
Identities = 117/310 (37%), Positives = 192/310 (61%), Gaps = 2/310 (0%)
Query: 270 LAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE-NVEDY- 327
+ ++ +++G V F Y + P+N ++Y +Q A +E ++++++DE V+D
Sbjct: 450 IVHEKTLTVGDYVLFTTYLLQLYTPLNFFGTIYRVIQKAFVDMENMFDLMNDEVEVKDLP 509
Query: 328 EGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMR 387
+ +G I +N+ FEY G PV+K+++ I VA+VG +G+GK+T+ L+ R
Sbjct: 510 HALPYTDPRGTISVKNLTFEYNTGLPVIKNISFEIGNGQTVALVGSSGSGKSTLIRLLFR 569
Query: 388 FYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIR 447
++ T+G I +DGID + + SLR++IG VPQ+T LF TIM NI P+A +E+VI
Sbjct: 570 LFESTEGSIEFDGIDVRNYTMHSLRQQIGIVPQDTVLFNDTIMYNIRFGRPDASDEEVIE 629
Query: 448 VCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVD 507
K IH+ I LP+GY T GE G LS GE+Q +++AR +LK P + LDEA S++D
Sbjct: 630 AAKAAMIHEKITSLPEGYATMVGERGLKLSGGEKQRVAIARTILKKPQFIFLDEATSALD 689
Query: 508 PKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
TE+ +Q + KL + RT +++AHRLS AD ++V+D G I+E G+ ELL+++G +
Sbjct: 690 TPTERAIQKCLEKLCKSRTGVVVAHRLSTVVNADLILVLDKGIILERGNHKELLAQQGTY 749
Query: 568 YKLYTSQMQE 577
++ +Q+ E
Sbjct: 750 ASMWEAQIAE 759
>emb|CAA71281.1| (Y10232) Tap1 protein [Rattus norvegicus]
Length = 725
Score = 229 bits (579), Expect = 5e-59
Identities = 163/578 (28%), Positives = 299/578 (51%), Gaps = 22/578 (3%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K + +L R + S++ L +V+V ++ S L +A P+ D +I+ + F
Sbjct: 144 KGAGDMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITD-WILQDKTAP-SF 201
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLD----FFKTKSTG 119
++L+ ++ +T F + + ++ S++H ++ ++ L FF TG
Sbjct: 202 ARNMWLMCILT--IASTALEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTG 259
Query: 120 DLVSRIINDTNVVNDVLVSGL---LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+ SR+ DT+ V + + L L LG L L + M+ LT+VTL S+PL+
Sbjct: 260 SITSRVTEDTSNVCESISDKLNLFLWYLGRGLCL---LAFMIWGSFYLTVVTLLSLPLLF 316
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
++ G + + ++ +AK + V E+++ + T+R+F E+ ++F + E
Sbjct: 317 LLPRRLGKVYQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKP 376
Query: 237 AYLRVAI-YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPI 295
+ A+ Y+ W M+++ +L + ++ GG L +GAVS G +V+F+ Y +F +
Sbjct: 377 LNKKEALAYVTEVWT-MSVSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAV 435
Query: 296 NNVVSMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEK--GR 352
++S+Y S+Q ++ A E+I+E LD G ++ +KG ++F++V F Y
Sbjct: 436 EVLLSIYPSMQKSVGASEKIFEYLDRTPCSPLSGSLAPLNMKGLVKFQDVSFAYPNHPNV 495
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VL+ + + P A+VG G+GK+T+A L+ Y PT+G++L DG + L
Sbjct: 496 QVLQGLTFTLYPGKVTALVGPNGSGKSTVAALLQNLYQPTRGKVLLDGEPLVQYDHHYLH 555
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKE-EDVIRVCKELGIHDFIMKLPKGYETSAGE 471
++ V QE LF + ENI E++ V E G HDFI P+GY+T GE
Sbjct: 556 TQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGE 615
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSII 529
G LS G+RQ ++LARA+++ P ++ILD+A S++D + VQ + + E RT ++
Sbjct: 616 TGNQLSGGQRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLL 675
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
I +LS+ A ++ + +G + E+G+ +L+ R G +
Sbjct: 676 ITQQLSLAERAHHILFLKEGSVCEQGTHLQLMERGGCY 713
>gb|AAC72026.1| (AF043280) ABC transporter [Streptococcus salivarius]
Length = 698
Score = 229 bits (579), Expect = 5e-59
Identities = 157/557 (28%), Positives = 280/557 (50%), Gaps = 15/557 (2%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K + L F+ + +A++V+ L N+ Y L+ ID I Y L
Sbjct: 146 KEDVPGLLSFLPILFRRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTM 205
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
I+ +S +AQ FT + + G + + + +L + FF ++ TG++ S
Sbjct: 206 ISHGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVILPYIKHVLSLPISFFSSRRTGEITS 265
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R D N + D L S +L + + + VA++L + L ++TLT VPL V+I L F
Sbjct: 266 RF-GDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLIILAFY 324
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+ + + +++++ V + + GIET+++ E+ +E + +K L A
Sbjct: 325 KLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAK 384
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
+ L L+S + ++ YG L +G +S G ++ + F P+ N++++
Sbjct: 385 WQLTQDGLKTGVQLVSNVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQS 444
Query: 304 SLQSALAALERIYE--ILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLY 361
+Q A A R+ E ++D E + S ++L + V + + L ++L
Sbjct: 445 KIQQAKVANNRLQEVYVVDKEEKGKLKEFSFKQL----ALKGVSHRFSYQQETLSKIDLT 500
Query: 362 IPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQE 421
I K+A++GK+G+GKTT+A ++ +Y + G + +D I LR+ + YVPQ+
Sbjct: 501 IHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVT---LDKDAIGHAELRQMVTYVPQQ 557
Query: 422 TYLFPGTIMENILMA-NPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
TY+F GTI+EN+L+ E E+ +++VC++ I + I K+P G++T E G LS G+
Sbjct: 558 TYVFTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGG-LSGGQ 616
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++ARA+L I+I DEA S +D TE V + K+ RT I IAHR S+ +
Sbjct: 617 KQRLAIARALLSKQPILIFDEATSGLDSDTESRVMANLAKIK--RTMIFIAHRNSVRQHV 674
Query: 541 DKVIVVDDGRIVEEGSP 557
+V+ + G+I E SP
Sbjct: 675 SRVVTMGGGQI-ESDSP 690
>gb|AAF47525.1| (AE003472) CG7955 gene product [alt 3] [Drosophila melanogaster]
>gi|7292114|gb|AAF47526.1| (AE003472) CG7955 gene
product [alt 2] [Drosophila melanogaster]
Length = 606
Score = 229 bits (579), Expect = 5e-59
Identities = 173/587 (29%), Positives = 290/587 (48%), Gaps = 36/587 (6%)
Query: 15 KEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYII------PGRYKELGFIAML- 67
KE R+ + I + + GS L + P++ + A+D P ML
Sbjct: 12 KEDPLVRKRVGISLGLLAGSKLLTVCVPFLFKGAVDTMTTLNMDTAPDAVLSAATALMLG 71
Query: 68 YLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIN 127
Y ++ + F L+ +R + S + + +L F K TG L I
Sbjct: 72 YGIARASAAGFNELRNAVFAKVAHHSIRKIASNVFLHLHNLDLAFHLNKQTGALSKTIDR 131
Query: 128 DTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTL-TSVPLMVIIALY----- 181
+ +N VL + + + +I LA + +L VK L S+ + I A Y
Sbjct: 132 GSRGINFVLSAMVFNIVPTIFELA---LVSSILGVKCGLAFAGVSMGCVGIYAAYTLSVT 188
Query: 182 -----FGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
F M +A E K +S+ ET++ F EK +++V +
Sbjct: 189 QWRTQFRVFMNQAENEAGNKAV-------DSLINYETVKYFNNEKYEAGCYNEVLKKYEA 241
Query: 237 AYLRVAIYMGI--FWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGP 294
A L+ + + + F +S LS+I+V+A +G +++G +V + P
Sbjct: 242 ASLKTSSSLALLNFGQNAIFSSALSLIMVLAAKEIA--QGNMTVGDLVMVNALLFQLSIP 299
Query: 295 INNVVSMYDSLQSALAALERIYEILD-DENVE---DYEGISVEKLKGEIEFRNVWFEYEK 350
+ + S+Y ++ AL + ++ +++ D +++ + + + V+ IEFRNV FEYE
Sbjct: 300 LGFLGSVYREVRQALLDMRAMFTLMNVDSSIQTAANAQPLFVDTTNSSIEFRNVSFEYEP 359
Query: 351 GRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS 410
G+P+ +D++ IP VAIVG +G+GK+++ L+ RF++P G++L G D + +S
Sbjct: 360 GKPIFRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLFRFFEPNSGKVLIGGQDISAVDLES 419
Query: 411 LRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAG 470
LRK I VPQ++ LF TI NI N +V + +HD IM P Y T G
Sbjct: 420 LRKVIAVVPQDSVLFHNTIEHNIHYGNLSKSHAEVQNAARMADLHDSIMSWPGQYSTQVG 479
Query: 471 EAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIII 530
E G LS GE+Q +++ARA+LK+ I+I DEA SS+D TE + A+ + GRTSI I
Sbjct: 480 ERGLKLSGGEKQRVAIARAILKNTPILIFDEATSSLDSITEHNILQALTRATSGRTSICI 539
Query: 531 AHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
AHRLS + AD+++V+++GR+ E G+ ELL + G + +L+ +Q Q+
Sbjct: 540 AHRLSTVKDADEILVLENGRVGERGTHSELLRQNGLYARLWETQTQQ 586
>emb|CAA40742.1| (X57523) mtp1 [Rattus norvegicus]
Length = 740
Score = 229 bits (578), Expect = 6e-59
Identities = 163/578 (28%), Positives = 292/578 (50%), Gaps = 22/578 (3%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYI----IPGRYK 59
K + +L R + S++ L +V+V ++ S L +A P+ D + P +
Sbjct: 159 KGAGDMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFAR 218
Query: 60 ELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTG 119
+ + +L + S V ++ + Y G R + ++ +L FF TG
Sbjct: 219 NMWLMCILTIASTVLEFAGDGI---YNITMGHMHSR-VHGEVFRAVLHQETGFFLKNPTG 274
Query: 120 DLVSRIINDTNVVNDVLVSGL---LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+ SR+ DT+ V + + L L LG L L + M+ LT+VTL S+PL+
Sbjct: 275 SITSRVTEDTSNVCESISDKLNLFLWYLGRGLCL---LAFMIWGSFYLTVVTLLSLPLLF 331
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
++ G + + ++ +AK + V E+++ + T+R+F E+ ++F + E
Sbjct: 332 LLPRRLGKVYQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKP 391
Query: 237 AYLRVAI-YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPI 295
+ A+ Y+ W M+++ +L + ++ GG L +GAVS G +V+F+ Y +F +
Sbjct: 392 LNKKEALAYVTEVWT-MSVSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAV 450
Query: 296 NNVVSMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEK--GR 352
++S+Y S+Q ++ A E+I+E LD G ++ +KG ++F++V F Y
Sbjct: 451 EVLLSIYPSMQKSVGASEKIFEYLDRTPCSPLSGSLAPLNMKGLVKFQDVSFAYPNHPNV 510
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VL+ + + P A+VG G+GK+T+A L+ Y PT G++L DG + L
Sbjct: 511 QVLQGLTFTLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLH 570
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKE-EDVIRVCKELGIHDFIMKLPKGYETSAGE 471
++ V QE LF + ENI E++ V E G HDFI P+GY+T GE
Sbjct: 571 TQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGE 630
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSII 529
G LS G+RQ ++LARA+++ P ++ILD+A S++D + VQ + + E RT ++
Sbjct: 631 TGNQLSGGQRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLL 690
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
I +LS+ A ++ + +G + E+G+ +L+ R G +
Sbjct: 691 ITQQLSLAERAHHILFLKEGSVCEQGTHLQLMERGGCY 728
>sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) >gi|111520|pir||S13426
multidrug resistance protein homolog - rat
>gi|1771566|emb|CAA71280.1| (Y10231) Tap1 protein
[Rattus norvegicus] >gi|227426|prf||1703417A mtp1
protein [Rattus norvegicus]
Length = 725
Score = 229 bits (578), Expect = 6e-59
Identities = 163/578 (28%), Positives = 292/578 (50%), Gaps = 22/578 (3%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYI----IPGRYK 59
K + +L R + S++ L +V+V ++ S L +A P+ D + P +
Sbjct: 144 KGAGDMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFAR 203
Query: 60 ELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTG 119
+ + +L + S V ++ + Y G R + ++ +L FF TG
Sbjct: 204 NMWLMCILTIASTVLEFAGDGI---YNITMGHMHSR-VHGEVFRAVLHQETGFFLKNPTG 259
Query: 120 DLVSRIINDTNVVNDVLVSGL---LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+ SR+ DT+ V + + L L LG L L + M+ LT+VTL S+PL+
Sbjct: 260 SITSRVTEDTSNVCESISDKLNLFLWYLGRGLCL---LAFMIWGSFYLTVVTLLSLPLLF 316
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
++ G + + ++ +AK + V E+++ + T+R+F E+ ++F + E
Sbjct: 317 LLPRRLGKVYQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKP 376
Query: 237 AYLRVAI-YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPI 295
+ A+ Y+ W M+++ +L + ++ GG L +GAVS G +V+F+ Y +F +
Sbjct: 377 LNKKEALAYVTEVWT-MSVSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAV 435
Query: 296 NNVVSMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEK--GR 352
++S+Y S+Q ++ A E+I+E LD G ++ +KG ++F++V F Y
Sbjct: 436 EVLLSIYPSMQKSVGASEKIFEYLDRTPCSPLSGSLAPLNMKGLVKFQDVSFAYPNHPNV 495
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VL+ + + P A+VG G+GK+T+A L+ Y PT G++L DG + L
Sbjct: 496 QVLQGLTFTLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLH 555
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKE-EDVIRVCKELGIHDFIMKLPKGYETSAGE 471
++ V QE LF + ENI E++ V E G HDFI P+GY+T GE
Sbjct: 556 TQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGE 615
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSII 529
G LS G+RQ ++LARA+++ P ++ILD+A S++D + VQ + + E RT ++
Sbjct: 616 TGNQLSGGQRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLL 675
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
I +LS+ A ++ + +G + E+G+ +L+ R G +
Sbjct: 676 ITQQLSLAERAHHILFLKEGSVCEQGTHLQLMERGGCY 713
>pir||T19982 hypothetical protein C47A10.1 - Caenorhabditis elegans
>gi|3875004|emb|CAB03973.1| (Z81484) contains similarity
to Pfam domain: PF00005 (ABC transporter), Score=450.7,
E-value=4.2e-132, N=2; PF00664 (ABC transporter
transmembrane region.), Score=399.8, E-value=8.4e-117,
N=2~cDNA EST yk303b9.3 comes from this gene~cDNA EST
yk303b9.5 c> >gi|3879215|emb|CAB07855.1| (Z93782)
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=450.7, E-value=4.2e-132, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=399.8, E-value=8.4e-117, N=2~cDNA EST yk303b9.3
comes from this gene~cDNA EST yk303b9.5 c>
Length = 1294
Score = 229 bits (577), Expect = 8e-59
Identities = 147/508 (28%), Positives = 253/508 (48%), Gaps = 21/508 (4%)
Query: 81 LQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGL 140
LQ V +K+ R Q +++ + ++ ++G L +++ ++ V +
Sbjct: 122 LQASCFMVICEKLSNRFRRQFFHSVMRQEIAWYDKNTSGTLSNKLFDNLERVRE------ 175
Query: 141 LGGLGSILSLAGIIVAMLL--------LDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
G G + LA ++A + D LTL+ ++ P M+I L+ + A +
Sbjct: 176 --GTGDKVGLAFQMMAQFIGGFAVAFTYDWLLTLIMMSLSPFMMICGLFLAKLLATAATK 233
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
++ A + EE + I T+ AF ++ K + K ++ + +G
Sbjct: 234 EAKQYAVAGGIAEEVLTSIRTVIAFNGQEYECKRYEDALEHGKKTGIKKSFLIGAGLASF 293
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+ S + G Y G + G V+ + + ++ +AL A
Sbjct: 294 FVIIYASYCLAFWVGTNFVYSGRLESGTVLTVFFSVMMGSMALGQAGQQFATIGTALGAA 353
Query: 313 ERIYEILDD-ENVEDY--EGISVEKLKGEIEFRNVWFEYEKGRPV--LKDVNLYIPPASK 367
+YE++D ++ Y EG + K+ G I V F Y V LK V+L P
Sbjct: 354 ASLYEVIDRIPEIDAYSTEGQTPSKISGRISVNKVEFTYPTRADVKILKGVSLDAQPGQT 413
Query: 368 VAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPG 427
VA+VG +G GK+TI L+ RFY+P G+IL D I + + K LR+ +G V QE LF
Sbjct: 414 VALVGSSGCGKSTIIQLLQRFYNPDAGQILIDDIPIEDFNIKYLRQLVGVVSQEPNLFNT 473
Query: 428 TIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLA 487
+I +NI + +ED+ R KE DFI P+G T G+ G +S G++Q I++A
Sbjct: 474 SIEQNIRYGRSDVSDEDIARALKEANAADFIKTFPEGLNTLVGDRGVQMSGGQKQRIAIA 533
Query: 488 RAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVD 547
RA++++P I++LDEA S++D ++E +VQ+A+ GRT+I+IAHRLS R ADK+IV+
Sbjct: 534 RALVRNPKILLLDEATSALDAESESIVQSALENASRGRTTIVIAHRLSTVRNADKIIVMK 593
Query: 548 DGRIVEEGSPGELLSRKGYFYKLYTSQM 575
G+++E G+ L+ +KG +++L +Q+
Sbjct: 594 AGQVMEVGTHETLIEQKGLYHELVHAQV 621
Score = 211 bits (531), Expect = 2e-53
Identities = 146/536 (27%), Positives = 261/536 (48%), Gaps = 18/536 (3%)
Query: 59 KELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTK-- 116
K+ F A+++L+ Q Q V +++ +RS+++ +L+ + +F
Sbjct: 744 KDGHFWALMFLVLAAVQGTSMLFQCSLFGVAAERLTMRIRSKVYRNVLRQDATYFDMPKH 803
Query: 117 STGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
S G + +R+ D + + L +I S+ G + ++ + + P M
Sbjct: 804 SPGRITTRLATDAPNIKSAIDYRLGSIFNAIASVGGGLGIAFYYGWQMAFLVMAIFPFMA 863
Query: 177 I----IALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVST 232
+ + Y GG +E + E++ I T++A + + F
Sbjct: 864 VGQALMMKYHGGSATSDAKE----MENAGKTAMEAIENIRTVQALTLQTKLYNIFCSHLD 919
Query: 233 ETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAY-KGAVSIGVVVAFIQYAQRF 291
+ AI G+ + N + +G +L + K + V + +A F
Sbjct: 920 APHGGNISKAIIRGLTYGFANSIQFFTYAAAFRFGLFLIFDKNVLMEPENVLRVLFAISF 979
Query: 292 R-GPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGIS--VEKLKGEIEFRNVWFEY 348
G I S + A A I+ +L++E D S +L GE++ V+F Y
Sbjct: 980 SFGTIGFAASYFPEYIKATFAAGLIFNMLEEEPRIDGMTSSGTYPQLSGEVKLNKVFFRY 1039
Query: 349 EK--GRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKI 406
+ P+L+ +N+++ P +A+VG +G GK+T+ +L+ R YDP +G + D D +++
Sbjct: 1040 PERPAVPILQGLNVHVKPGQTLALVGPSGCGKSTVISLLERLYDPLEGAVTVDNNDLRQM 1099
Query: 407 SRKSLRKRIGYVPQETYLFPGTIMENIL--MANPEAKEEDVIRVCKELGIHDFIMKLPKG 464
+ K LRK I V QE LF +I ENI+ + E E + C + IH FI +LP G
Sbjct: 1100 NPKHLRKHIALVSQEPILFDTSIRENIVYGLQPGEYTHEQIETACSKANIHKFIDELPDG 1159
Query: 465 YETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEG 524
YET GE G LS G++Q I++ARA++++P I++LDEA S++D ++E+ VQ A+ +
Sbjct: 1160 YETRVGEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTESEKQVQVALDAAAKD 1219
Query: 525 RTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEVPG 580
RT I++AHRLS A ++VV +G++VE+G+ EL++++G ++ L Q G
Sbjct: 1220 RTCIVVAHRLSTIVNAGCIMVVKNGQVVEQGTHNELIAKRGAYFALTQKQSSNQSG 1275
>emb|CAA71282.1| (Y10233) Tap1 protein [Rattus norvegicus]
Length = 725
Score = 228 bits (575), Expect = 1e-58
Identities = 162/578 (28%), Positives = 292/578 (50%), Gaps = 22/578 (3%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYI----IPGRYK 59
K + +L R + S++ L +V+V ++ S L +A P+ D + P +
Sbjct: 144 KGAGDMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFAR 203
Query: 60 ELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTG 119
+ + +L + S ++ + Y G R + ++ +L FF TG
Sbjct: 204 NMWLMCILTIASSALEFAGDGI---YNITMGHMHSR-VHGEVFRAVLHQETGFFLKNPTG 259
Query: 120 DLVSRIINDTNVVNDVLVSGL---LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+ SR+ DT+ V + + L L LG L L + M+ LT+VTL S+PL+
Sbjct: 260 SITSRVTEDTSNVCESISDKLNLFLWYLGRGLCL---LAFMIWGSFYLTVVTLLSLPLLF 316
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
++ G + + ++ +AK + V E+++ + T+R+F E+ ++F + E
Sbjct: 317 LLPRRLGKVYQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKP 376
Query: 237 AYLRVAI-YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPI 295
+ A+ Y+ W M+++ +L + ++ GG L +GAVS G +V+F+ Y +F +
Sbjct: 377 LNKKEALAYVTEVWT-MSVSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAV 435
Query: 296 NNVVSMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEK--GR 352
++S+Y S+Q ++ A E+I+E LD G ++ +KG ++F++V F Y
Sbjct: 436 EVLLSIYPSMQKSVGASEKIFEYLDRTPCSPLSGSLAPLNMKGLVKFQDVSFAYPNHPNV 495
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VL+ + + P A+VG G+GK+T+A L+ Y PT G++L DG + L
Sbjct: 496 QVLQGLTFTLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLH 555
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKE-EDVIRVCKELGIHDFIMKLPKGYETSAGE 471
++ V QE LF + ENI E++ V E G HDFI P+GY+T GE
Sbjct: 556 TQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGE 615
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSII 529
G LS G+RQ ++LARA+++ P ++ILD+A S++D + VQ + + E RT ++
Sbjct: 616 TGNQLSGGQRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLL 675
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
I +LS+T A ++ + +G + E+G+ +L+ + G +
Sbjct: 676 ITQQLSLTERAHHILFLKEGSVCEQGTHLQLMEKGGCY 713
>emb|CAA71284.1| (Y10235) Tap1 protein [Rattus norvegicus]
Length = 725
Score = 227 bits (572), Expect = 3e-58
Identities = 162/578 (28%), Positives = 298/578 (51%), Gaps = 22/578 (3%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K + +L R + S++ L +V+V ++ S L +A P+ D +I+ + F
Sbjct: 144 KGAGDMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITD-WILQDKTAP-SF 201
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLD----FFKTKSTG 119
++L+ ++ +T F + + ++ S++H ++ ++ L FF TG
Sbjct: 202 ARNMWLMCILT--IASTALEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTG 259
Query: 120 DLVSRIINDTNVVNDVLVSGL---LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+ SR+ DT+ V + + L L LG L L + M+ LT+VTL S+PL+
Sbjct: 260 SITSRVTEDTSNVCESISDKLNLFLWYLGRGLCL---LAFMIWGSFYLTVVTLLSLPLLF 316
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
++ G + + ++ +AK + V E+++ + T+R+F E+ ++F + E
Sbjct: 317 LLPRRLGKVYQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKP 376
Query: 237 AYLRVAI-YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPI 295
+ A+ Y+ W M+++ +L + ++ GG L +GAVS G +V+F+ Y +F +
Sbjct: 377 LNKKEALAYVTEVWT-MSVSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAV 435
Query: 296 NNVVSMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEK--GR 352
++S+Y S+Q ++ A E+I+E LD G ++ +KG ++F++V F Y
Sbjct: 436 EVLLSIYPSMQKSVGASEKIFEYLDRTPCSPLSGSLAPLNMKGLVKFQDVSFAYPNHPNV 495
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VL+ + + P ++VG G+GK+T+A L+ Y PT G++L DG + L
Sbjct: 496 QVLQGLTFTLYPGKVTSLVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLH 555
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKE-EDVIRVCKELGIHDFIMKLPKGYETSAGE 471
++ V QE LF + ENI E++ V E G HDFI P+GY+T GE
Sbjct: 556 TQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGE 615
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSII 529
G LS G+RQ ++LARA+++ P ++ILD+A S++D + VQ + + E RT ++
Sbjct: 616 TGNQLSGGQRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLL 675
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
I +LS+ A ++ + +G + E+G+ +L+ R G +
Sbjct: 676 ITQQLSLAERAHHILFLKEGSVCEQGTHLQLMERGGCY 713
>gb|AAF55241.1| (AE003710) CG4225 gene product [Drosophila melanogaster]
Length = 866
Score = 227 bits (572), Expect = 3e-58
Identities = 168/594 (28%), Positives = 291/594 (48%), Gaps = 49/594 (8%)
Query: 15 KEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLV- 73
K+ ++ + + + ++ ++ + L P + +D I F+ + LS +
Sbjct: 242 KKNIALQIAVIVCIILLLAGRVIKLFLPIYRKKLVDSLTIAPIVFRWDFVLIYVALSFLQ 301
Query: 74 -----AQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
+ F L+TF Q R + +L + Q +L + + TG+++ +
Sbjct: 302 GGGTGSMGLFNNLRTFLWIRVQQYTTREIEIELFRHLHQLSLRWHLQRKTGEVLRVMDRG 361
Query: 129 TNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRR 188
T+ +N++L + S+A I+ +L+ L+V + ++
Sbjct: 362 TDSINNLLNY-------IVFSIAPTILDLLVAVAYFVYAFNWWFGLIVFLTMFLYIASTI 414
Query: 189 AYRETRQKIAKISSVVE--------ESVAGIETIRAFGKE------------KDVEKEF- 227
A E R K + ++ + +S+ ET++ +G E K ++EF
Sbjct: 415 AITEWRTKYQRRMNLADNEQRARSVDSLLNFETVKYYGAEHYEVDCYREAILKYQKEEFL 474
Query: 228 SKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQY 287
S ++ + + + +G+ SLL V +V+ + +++G V F Y
Sbjct: 475 SMLTLNMLNTAQNIILCLGLL-----AGSLLCVYLVV-------HHQTLTVGDFVLFSTY 522
Query: 288 AQRFRGPINNVVSMYDSLQSALAALERIYEIL-DDENVEDYEGIS-VEKLKGEIEFRNVW 345
P+N + Y ++Q +E ++++L ++E + D G S + G IEF NV
Sbjct: 523 LMELYMPLNWFGTYYRAIQKNFVDMENMFDLLKEEEEIVDAPGCSPLLTAGGGIEFSNVT 582
Query: 346 FEYEKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKK 405
F Y + VL++V+ +P VAIVG +GAGK+TI L+ RFYD G IL DG + K
Sbjct: 583 FGYSPEKIVLRNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKL 642
Query: 406 ISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGY 465
+ ++SLRK IG VPQ+T LF TI NI A A +E V + IH+ I+ P+ Y
Sbjct: 643 VQQQSLRKAIGVVPQDTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGFPEKY 702
Query: 466 ETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGR 525
ET GE G LS GE+Q +++AR +LK P IV+LDEA S++D TE+ +Q A+ ++ R
Sbjct: 703 ETKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEATSALDTHTERNIQAALARVCANR 762
Query: 526 TSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRK-GYFYKLYTSQMQEV 578
T+II+AHRLS AD+++V+ G I E G EL+ R+ G + ++ Q++ +
Sbjct: 763 TTIIVAHRLSTIIHADEILVLQQGSIAERGRHEELVLREDGIYADMWQQQLKNL 816
>emb|CAA71279.1| (Y10230) Tap1 protein [Rattus norvegicus]
>gi|1771572|emb|CAA71283.1| (Y10234) Tap1 protein
[Rattus norvegicus]
Length = 725
Score = 226 bits (571), Expect = 4e-58
Identities = 163/578 (28%), Positives = 298/578 (51%), Gaps = 22/578 (3%)
Query: 4 KSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGF 63
K + +L R + S++ L +V+V ++ S L +A P+ D +I+ + F
Sbjct: 144 KGAGDMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITD-WILQDKTAP-SF 201
Query: 64 IAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLD----FFKTKSTG 119
++L+ ++ +T F + + ++ S++H ++ ++ L FF TG
Sbjct: 202 ARNMWLMCILT--VASTALEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTG 259
Query: 120 DLVSRIINDTNVVNDVLVSGL---LGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
+ SR+ DT+ V + + L L LG L L + M+ LT+VTL S+PL+
Sbjct: 260 SITSRVTEDTSNVCESISDKLNLFLWYLGRGLCL---LAFMIWGSFYLTVVTLLSLPLLF 316
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
++ G + + ++ +AK + V E+++ + T+R+F E+ ++F + E
Sbjct: 317 LLPRRLGKVYQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKP 376
Query: 237 AYLRVAI-YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPI 295
+ A+ Y+ W M+++ +L + ++ GG L +GAVS G +V+F+ Y +F +
Sbjct: 377 LNKKEALAYVTEVWT-MSVSGMLLKVGILYLGGQLVVRGAVSSGNLVSFVLYQLQFTRAV 435
Query: 296 NNVVSMYDSLQSALAALERIYEILDDENVEDYEG-ISVEKLKGEIEFRNVWFEYEK--GR 352
++S+Y S+Q ++ A E+I+E LD G ++ +KG ++F++V F Y
Sbjct: 436 EVLLSIYPSMQKSVGASEKIFEYLDRTPCSPLSGSLAPLNMKGLVKFQDVSFAYPNHPNV 495
Query: 353 PVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLR 412
VL+ + + P A+VG G+GK+T+A L+ Y PT G++L DG + L
Sbjct: 496 QVLQGLTFTLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGELLVQYDHHYLH 555
Query: 413 KRIGYVPQETYLFPGTIMENILMANPEAKE-EDVIRVCKELGIHDFIMKLPKGYETSAGE 471
++ V QE LF + ENI E++ V E G HDFI P+GY+T GE
Sbjct: 556 TQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGE 615
Query: 472 AGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLME--GRTSII 529
G LS G+RQ ++LARA+++ P ++ILD+A S++D + VQ + + E RT ++
Sbjct: 616 TGNQLSGGQRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESPEWASRTVLL 675
Query: 530 IAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYF 567
I +LS+ A ++ + +G + E+G+ +L+ R G +
Sbjct: 676 ITQQLSLAERAHHILFLKEGSVCEQGTHLQLMERGGCY 713
>gb|AAF71764.1|AF263912_3 (AF263912) NysH [Streptomyces noursei]
Length = 584
Score = 225 bits (567), Expect = 1e-57
Identities = 151/565 (26%), Positives = 278/565 (48%), Gaps = 18/565 (3%)
Query: 23 TLAIVVVSIVGSALANLASPYILRVAIDHYIIPG---RYKELGFI-AMLYLLSLVAQWFF 78
T A+V + +V L L P + ID ++ G R ELG + ++ L+ + A
Sbjct: 17 TAALVALQLV-QILGTLLLPTLGAALIDQGVVRGDGGRITELGVVMGVVALVQIAAALGA 75
Query: 79 TTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVS 138
L G R+LRS L +IL + T L++R +ND V ++ +
Sbjct: 76 AALAARTATAMG----RDLRSALFRRILDFSAREIGRFGTPSLLTRSVNDVQQVQNLAQT 131
Query: 139 GLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG---GKMRRAYRETRQ 195
G + + L G ++ L DV L L+ V L++++A+ FG +M Y +
Sbjct: 132 GFGIVVCAPLMCLGSVLLALRQDVPLALLL---VALVLVVAVCFGLLLARMGTLYARMQL 188
Query: 196 KIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIA 255
+ ++ ++ E++ G+ +R+F ++ F++ + + RV + P++ +
Sbjct: 189 TLDRLGRLLREAITGVRVVRSFVRDDHERARFAQTNDAFLVVSRRVGRLIATMLPVVLLL 248
Query: 256 SLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERI 315
+ ++ G + G + IG + A + Y + + ++ S+ A RI
Sbjct: 249 MNGFTVALLWTGSHRIDAGRMPIGSLSALLSYLSLILMSVVMLAFVFLSVPRARVCAGRI 308
Query: 316 YEILDDEN--VEDYEGISVEKLKGEIEFRNVWFEYEKGR-PVLKDVNLYIPPASKVAIVG 372
E+LD + V G IE + Y PVL+DV+L + P ++A++G
Sbjct: 309 AEVLDTGSSVAPPAAPQPVRGPAGRIELCAAGYRYPGAEEPVLRDVDLTVEPGERIAVLG 368
Query: 373 KTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMEN 432
TG+GKTT+ NL++R D T+G + G D ++++ +L +G+VPQ YLF GT+ N
Sbjct: 369 STGSGKTTLLNLVLRLADATEGAVRVGGTDVRELTAATLAAAVGFVPQRPYLFSGTVASN 428
Query: 433 ILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLK 492
+ P+A +E++ + DF+ ++P G + + G +S G+RQ +SLARA+L+
Sbjct: 429 LRFGRPDATDEELWEALRVAQAADFVARMPDGLDAEITQGGGNVSGGQRQRLSLARALLR 488
Query: 493 DPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIV 552
P+I + D+ S++D T+ ++ A++ G T I +A R+S R AD+++V+D GR+V
Sbjct: 489 RPEIYLFDDCFSALDQATDAALRTALVPYTAGATVITVAQRISAGRDADRIVVLDRGRVV 548
Query: 553 EEGSPGELLSRKGYFYKLYTSQMQE 577
+G+ LL + ++ SQ+ E
Sbjct: 549 AQGTHDVLLRTSPTYREIALSQLTE 573
>gb|AAD10394.1| (U46488) NrpB [Proteus mirabilis]
Length = 575
Score = 224 bits (566), Expect = 2e-57
Identities = 174/586 (29%), Positives = 310/586 (52%), Gaps = 35/586 (5%)
Query: 9 LLKRFIKEA--LSERRTLAIVV---VSIVGSALANLASPYILR--VAIDHYIIPGRYKEL 61
++K IK LS ++ ++V +++V A + PYIL + ID + +L
Sbjct: 1 MIKELIKSGYLLSNKKDKDLMVGLCLAVVEGLFATI--PYILLYFLLIDLFANKITLAQL 58
Query: 62 GFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDL 121
+ + LLS+V + T + K++ R ++ + + + + +F ++ +GDL
Sbjct: 59 FYYFLSILLSIVLRIVIGTYSMPMIFIGAYKMMGQARLRIADHLRKIPIGWFSSQRSGDL 118
Query: 122 VSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLL-LDVKLTLVTLTSVPLMVIIAL 180
SR+ D ++ ++ S LG S L++ + L+ +D +LTL+ L S+P+ + AL
Sbjct: 119 ASRLTADLEIIQNIW-SHFLGMFISTLAMPVFLSLFLVWVDWQLTLIILFSIPI-ALFAL 176
Query: 181 YFGGK-MRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTET----- 234
K M +A ++ A + S + + + GI IR+FG+ K+ K + ET
Sbjct: 177 SISHKIMLKAAQQAADANANVQSELLDYIQGIMVIRSFGRLGPAWKKL-KAALETQNKTQ 235
Query: 235 IKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQ-----YAQ 289
I + A ++ ++ ++ +L +I+ G G++S V F+ Y Q
Sbjct: 236 IVLDSKPAPWIALYGFILESGFILLMII----GTSRLISGSLSPSQFVFFLVLALPIYRQ 291
Query: 290 RFRGPINNVVSMYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYE 349
F +++++ Y A +L+RI E++ + + + + ++ +I F NV F Y
Sbjct: 292 FFDLGLSSMLLNY-----AQKSLQRIEEVMKVVPLSEPKYTQLP-IRTDIYFNNVSFIYP 345
Query: 350 -KGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISR 408
+ L +++ P S AIVG +G+GK+T+ LI R +D +GEIL D I+ +I+
Sbjct: 346 YNSQLTLDNISCCFPEKSFTAIVGPSGSGKSTLLQLISRLWDVNQGEILLDDININQINS 405
Query: 409 KSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETS 468
L + V Q+ LF GTI +NILM +A ++++I K H+FI++ P+ Y+T
Sbjct: 406 DKLCSYVSSVYQDVVLFSGTIKDNILMGKTDAHDDEIITAAKLANAHEFIIQKPQNYDTP 465
Query: 469 AGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSI 528
G G LLS GERQ +SLAR +LK+ I+++DEA SS+D +E L+Q A+ L + +T I
Sbjct: 466 IGYGGMLLSGGERQRLSLARTLLKNAPILLIDEATSSIDCSSEVLIQQALSLLSKDKTII 525
Query: 529 IIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+IAHRL+ + AD +IV+++G+I E+G ELL++ G + L+ Q
Sbjct: 526 MIAHRLNSIKNADNIIVMENGKIAEQGKHAELLAKNGLYAHLWLQQ 571
>gb|AAF04885.1|AC010796_21 (AC010796) putative ABC transporter; 73228-76244 [Arabidopsis
thaliana]
Length = 438
Score = 224 bits (566), Expect = 2e-57
Identities = 142/440 (32%), Positives = 238/440 (53%), Gaps = 14/440 (3%)
Query: 146 SILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKISSVVE 205
++L G ++ +L+L L L TL ++ + +G ++ + ++ A + V +
Sbjct: 5 NVLQGTGALIYLLILSWPLGLCTLVICCILAAVMFVYGMYQKKTAKLIQEITASANEVAQ 64
Query: 206 ESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIA 265
E+ + + T+R +G EK K ++ LR + GI+ N + I+ +
Sbjct: 65 ETYSLMRTVRVYGTEKQEFKRYNHWLQRLADISLRQSAAYGIWNWSFNTLYHATQIIAVL 124
Query: 266 YGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDENVE 325
GG G ++ + F+ Y++ V SL ++ A E++++++D +
Sbjct: 125 VGGLSILAGQITAEQLTKFLLYSEWLIYATWWVGDNLSSLMQSVGASEKVFQMMDLK--- 181
Query: 326 DYEGISVEKLKGEIEFRNVWFEYEKGRPV--LKDVNLYIPPASKVAIVGKTGAGKTTIAN 383
+++L G IEF +V F Y V +++VN+ + P VAIVG +G+GK+T+ N
Sbjct: 182 --PRTRLQRLTGHIEFVDVSFSYPSRDEVAVVQNVNISVHPGEVVAIVGLSGSGKSTLVN 239
Query: 384 LIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILM-ANPEAKE 442
L+++ Y+PT G+IL DG+ K++ K LR+RIGYV QE LF I NI + +
Sbjct: 240 LLLQLYEPTSGQILLDGVPLKELDVKWLRQRIGYVGQEPKLFRTDISSNIKYGCDRNISQ 299
Query: 443 EDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEA 502
ED+I K+ HDFI LP GY T + LLS G++Q I++ARA+L+DP I+ILDEA
Sbjct: 300 EDIISAAKQAYAHDFITALPNGYNTIVDD--DLLSGGQKQRIAIARAILRDPRILILDEA 357
Query: 503 LSSVDPKTEQLVQNAMIKL----MEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPG 558
S++D ++E V+ + + R+ I+IAHRLS + AD+++ +D GR+VE GS
Sbjct: 358 TSALDAESEHNVKGVLRSIGNDSATKRSVIVIAHRLSTIQAADRIVAMDSGRVVEMGSHK 417
Query: 559 ELLSRKGYFYKLYTSQMQEV 578
ELLS+ G + +L Q V
Sbjct: 418 ELLSKDGLYARLTKRQNDAV 437
>gb|AAB00463.1| (L26955) transport protein [Streptomyces verticillus]
>gi|1093573|prf||2104260G transport protein
[Streptomyces verticillus] >gi|1093580|prf||2104261G
transport protein [Streptomyces verticillus]
Length = 604
Score = 223 bits (563), Expect = 4e-57
Identities = 156/576 (27%), Positives = 293/576 (50%), Gaps = 31/576 (5%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
+L RF++ RR L + +V +G+ +A LA+P + + +D + + IA+L
Sbjct: 29 VLWRFVRP---HRRALLLGLVLGLGTTMAQLATPLVTKGVLDG--LDAQAPVGPAIALLV 83
Query: 69 LLSLV------AQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLV 122
L LV A+W ++++ + RS + ++L++ + +S+G++V
Sbjct: 84 ALLLVGTGCALAEWILLG-------GLAERIVLDARSAMVRRLLRARVTALSGRSSGEIV 136
Query: 123 SRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYF 182
+R+ +DT ++ + + + + + + L G +V M LD L TL ++ ++ +
Sbjct: 137 TRVTSDTLLLREAAATSAVDLVNAAVLLVGALVLMGTLDWVLLATTLGAIAVIGAVVAVL 196
Query: 183 GGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKV---STETIKAYL 239
M A RE + + ++ V+E ++ I T++A G+ +D ++ +K+ + E+ + +
Sbjct: 197 MPPMAVAQREAQAAVGRLGGVLEGTLRAIRTVKA-GRAED--RQCAKILAEARESTRQSI 253
Query: 240 RVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVV 299
R + + W + ++++ V+A G + +G + + +VAF+ YA + P+ ++
Sbjct: 254 RAVRFEAVAWTVATGGIHIAILAVLALGAWRVTEGVLPVSSLVAFLLYAFQILDPVTSLT 313
Query: 300 SMYDSLQSALAALERIYEI--LDDENVEDYEGISVEKLKGE--IEFRNVWFEYE-KGRPV 354
Q+ AA RI E+ ++ E + + G + FRNV + G P
Sbjct: 314 RTVSQFQAGTAAAARIGEVQTMEAEPLSTPRAPAPRGAIGHHIVTFRNVTARHRPDGPPT 373
Query: 355 LKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKR 414
L D+ IP A+VG +GAGKTT+ +L++ F P GE+ DG + ++R R
Sbjct: 374 LSDITFGIPRRGHTAVVGPSGAGKTTLFSLLLGFLQPQHGELALDGRPFAQWPLDAIRAR 433
Query: 415 IGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGK 474
+ YV Q+ L PGT+ EN+L + E ++ + V + + + D L G +T +
Sbjct: 434 MAYVEQDAPLLPGTLRENLLCRHREVDDDTLWTVLRAVRLEDRTRALRDGLDTVLTDTA- 492
Query: 475 LLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRL 534
LS GERQ I+LARA++ DPD+++LDEA + +D TE V++ + R + IAHRL
Sbjct: 493 -LSGGERQRIALARALVGDPDLLLLDEATAQLDGLTEVAVRDVVRHTAARRAVVTIAHRL 551
Query: 535 SITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKL 570
S AD+++V+D GR+ G+ +LL R + L
Sbjct: 552 STVSDADRILVLDRGRLRALGTHTQLLGRDALYRDL 587
>gb|AAF73656.1| (AE002196) ABC transporter, ATP-binding protein [Chlamydophila
pneumoniae AR39] >gi|8978785|dbj|BAA98621.1| (AP002546)
Transport ATP Binding Protein [Chlamydophila pneumoniae
J138]
Length = 659
Score = 222 bits (560), Expect = 8e-57
Identities = 156/577 (27%), Positives = 289/577 (50%), Gaps = 19/577 (3%)
Query: 1 MADKSSLSLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKE 60
++ K L + K++ + + + A ++ G + A+L S L + +YI R++
Sbjct: 67 LSQKDILENWQAISKDSETLKVSDATTYIAEHGKSTASLTSK--LSKFVRNYIDVSRFRG 124
Query: 61 LGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD 120
L + + FF Q F +V +V R+LR + + Q + FF G+
Sbjct: 125 LAIFLICVAIFKAVTLFF---QRFLGQVVAIRVSRDLRQDYFKALQQLPMTFFHDHDIGN 181
Query: 121 LVSRIINDTN----VVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV 176
L +R++ D+ VN ++++ + + IL+L L + K +++ + P+ +
Sbjct: 182 LSNRVMTDSASIALAVNSLMINYIQAPITFILTLG----VCLSISWKFSILICVAFPIFI 237
Query: 177 IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIK 236
+ + K++ + ++ SSV+ + +AG+ T++ F EK ++ + + +
Sbjct: 238 LPIVVIARKIKNLAKRIQKSQDSFSSVLYDFLAGVMTVKVFRTEKFAFTKYCEHNNKISA 297
Query: 237 AYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPIN 296
+ A Y + PL++ + L V+ G YK A+ ++ F PI
Sbjct: 298 LEEKSAAYGLLPRPLLHTIASLFFAFVVVIG---IYKFAIPPEELIVFCGLLYLIYDPIK 354
Query: 297 NVVSMYDSLQSALAALERIYEILDDENVEDYEGISVE--KLKGEIEFRNVWFEYEKGRPV 354
S+ AA ER YE+L+ ++ + +E L I F NV F Y++ + +
Sbjct: 355 KFGDENTSIMRGCAAAERFYEVLNHPDLHSQKEREIEFLGLSNTITFENVSFGYQEDKHI 414
Query: 355 LKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKR 414
LK+++ + + IVG TG+GKTT+ L+ R Y+ ++G+IL D + + ++ SLR
Sbjct: 415 LKNLSFTLHKGEALGIVGPTGSGKTTLVKLLPRLYEVSQGKILIDSLPITEYNKGSLRNH 474
Query: 415 IGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGK 474
I V Q +LF T+ N L + +EE V+ K +FI+KLPKG + E+GK
Sbjct: 475 IACVLQNPFLFYDTVWNN-LTCGKDMEEEAVLEALKRAYADEFILKLPKGVHSVLEESGK 533
Query: 475 LLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRL 534
LS G++Q +++ARA+LK+ I+ILDEA S++D +E ++N + +L T IIIAH+L
Sbjct: 534 NLSGGQQQRLAIARALLKNASILILDEATSALDAISENYIKNIIGELKGQCTQIIIAHKL 593
Query: 535 SITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLY 571
+ D+V+ +++G+ + EG+ ELL F K++
Sbjct: 594 TTLEHVDRVLYIENGQKIAEGTKEELLQTCPEFLKMW 630
>gi|9961246 ATP-binding cassette, sub-family B, member 3, isoform 2;
transporter 2, ABC (ATP binding cassette); antigen
peptide transporter 2 [Homo sapiens]
>gi|106985|pir||B41538 ABC-type transport protein TAP2 -
human >gi|188506|gb|AAA59841.1| (M74447) putative
peptide pump; putative [Homo sapiens]
Length = 703
Score = 222 bits (559), Expect = 1e-56
Identities = 144/551 (26%), Positives = 283/551 (51%), Gaps = 15/551 (2%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
L+ R +K + + L +V + L P+ ID I+ G + F + ++
Sbjct: 137 LMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVID--ILGGDFDPHAFASAIF 194
Query: 69 LLSLVAQWFFTTLQT-----FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+ L + F ++L +T + LR +R QL +L+ +L FF+ TG+L S
Sbjct: 195 FMCLFS--FGSSLSAGCRGGCFTYTMSRINLR-IREQLFSSLLRQDLGFFQETKTGELNS 251
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ +DT ++++ L L S++ + G+ ML + +LTL++L +P + +
Sbjct: 252 RLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYN 311
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+ + RE + +A+ VV E+V G++T+R+FG E+ + + + + Y R +
Sbjct: 312 TRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDL 371
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
++ + + L +++++ G G ++ G +++F+ Y + + +V +Y
Sbjct: 372 ERALYLLIRRVLHLGVQMLMLSCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYG 431
Query: 304 SLQSALAALERIYEILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEK--GRPVLKDVNL 360
+ S + A E+++ +D + N+ ++ L+G ++F++V F Y RPVLK +
Sbjct: 432 DMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTF 491
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+ P A+VG G+GK+T+A L+ Y PT G++L D + L ++ V Q
Sbjct: 492 TLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQ 551
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
E LF G++ NI +++ V+ + DFI ++ G T GE G L+ G+
Sbjct: 552 EPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQ 611
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++ARA+++DP ++ILDEA S++D + EQ +Q+ + RT ++IAHRL + A
Sbjct: 612 KQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSR--GDRTVLVIAHRLQAVQRA 669
Query: 541 DKVIVVDDGRI 551
+++V+ +G++
Sbjct: 670 HQILVLQEGKL 680
>dbj|BAA96918.1| (AB019228) ABC transporter-like protein [Arabidopsis thaliana]
>gi|9964121|gb|AAG09829.1|AF287699_1 (AF287699)
half-molecule ABC transporter ATM3 [Arabidopsis
thaliana]
Length = 728
Score = 222 bits (559), Expect = 1e-56
Identities = 152/505 (30%), Positives = 255/505 (50%), Gaps = 18/505 (3%)
Query: 86 TEVFGQKVLRNLRS---QLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLG 142
T VF + LR +RS ++ + +L + ++ TG L I + +N +L + +
Sbjct: 220 TAVFSKVALRTIRSVSRKVFSHLHDLDLRYHLSRETGGLNRIIDRGSRAINFILSAMVFN 279
Query: 143 GLGSILSLAGII-VAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKIS 201
+ +IL ++ + + +T SV ++ L + R +R+ K +
Sbjct: 280 VVPTILEISMVSGILAYKFGAAFAWITSLSVGSYIVFTLAVT-QWRTKFRKAMNKADNDA 338
Query: 202 SV-VEESVAGIETIRAF---GKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLMNIASL 257
S +S+ ET++ F G E + +F K + R ++ F + ++
Sbjct: 339 STRAIDSLINYETVKYFNNEGYEAEKYDQFLKKYEDAALQTQRSLAFLN-FGQSIIFSTA 397
Query: 258 LSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYE 317
LS +V+ G + G +++G +V + P+N + S+Y +L ++ +++
Sbjct: 398 LSTAMVLCSQGIM--NGQMTVGDLVMVNGLLFQLSLPLNFLGSVYRETIQSLVDMKSMFQ 455
Query: 318 ILDDE----NVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPASKVAIVGK 373
+L+++ N D + + ++ G IEF NV F Y R +L ++ +P VAIVG
Sbjct: 456 LLEEKSDITNTSDAKPLVLKG--GNIEFENVHFSYLPERKILDGISFVVPAGKSVAIVGT 513
Query: 374 TGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENI 433
+G+GK+TI ++ RF+D G I DG D K++ SLR IG VPQ+T LF TI NI
Sbjct: 514 SGSGKSTILRMLFRFFDTDSGNIRIDGQDIKEVRLDSLRSSIGVVPQDTVLFNDTIFHNI 573
Query: 434 LMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAMLKD 493
A EE+V + IH+ I P Y T GE G LS GE+Q ++LAR LK
Sbjct: 574 HYGRLSATEEEVYEAARRAAIHETISNFPDKYSTIVGERGLKLSGGEKQRVALARTFLKS 633
Query: 494 PDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVE 553
P I++ DEA S++D TE + NA+ L RTSI IAHRL+ D+++V+++G++VE
Sbjct: 634 PAILLCDEATSALDSTTEAEILNALKALASNRTSIFIAHRLTTAMQCDEIVVLENGKVVE 693
Query: 554 EGSPGELLSRKGYFYKLYTSQMQEV 578
+G ELL + G + +L+T Q V
Sbjct: 694 QGPHDELLGKSGRYAQLWTQQNSSV 718
>gi|11417922 ATP-binding cassette, sub-family B, member 3, isoform 1 [Homo
sapiens] >gi|549044|sp|Q03519|TAP2_HUMAN ANTIGEN PEPTIDE
TRANSPORTER 2 (APT2) (PEPTIDE TRANSPORTER TAP2) (PEPTIDE
TRANSPORTER PSF2) (PEPTIDE SUPPLY FACTOR 2) (PSF-2)
(PEPTIDE TRANSPORTER INVOLVED IN ANTIGEN PROCESSING 2)
>gi|34638|emb|CAA47027.1| (X66401)
ABC-transporter~peptide pump [Homo sapiens]
>gi|1054748|emb|CAA60788.1| (X87344) TAP2 [Homo sapiens]
Length = 686
Score = 221 bits (558), Expect = 1e-56
Identities = 144/551 (26%), Positives = 283/551 (51%), Gaps = 15/551 (2%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
L+ R +K + + L +V + L P+ ID I+ G + F + ++
Sbjct: 137 LMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVID--ILGGDFDPHAFASAIF 194
Query: 69 LLSLVAQWFFTTLQT-----FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+ L + F ++L +T + LR +R QL +L+ +L FF+ TG+L S
Sbjct: 195 FMCLFS--FGSSLSAGCRGGCFTYTMSRINLR-IREQLFSSLLRQDLGFFQETKTGELNS 251
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ +DT ++++ L L S++ + G+ ML + +LTL++L +P + +
Sbjct: 252 RLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYN 311
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+ + RE + +A+ VV E+V G++T+R+FG E+ + + + + Y R +
Sbjct: 312 TRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDL 371
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
++ + + L +++++ G G ++ G +++F+ Y + + +V +Y
Sbjct: 372 ERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYG 431
Query: 304 SLQSALAALERIYEILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEK--GRPVLKDVNL 360
+ S + A E+++ +D + N+ ++ L+G ++F++V F Y RPVLK +
Sbjct: 432 DMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTF 491
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+ P A+VG G+GK+T+A L+ Y PT G++L D + L ++ V Q
Sbjct: 492 TLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQ 551
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
E LF G++ NI +++ V+ + DFI ++ G T GE G L+ G+
Sbjct: 552 EPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQ 611
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++ARA+++DP ++ILDEA S++D + EQ +Q+ + RT ++IAHRL + A
Sbjct: 612 KQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSR--GDRTVLVIAHRLQTVQRA 669
Query: 541 DKVIVVDDGRI 551
+++V+ +G++
Sbjct: 670 HQILVLQEGKL 680
>emb|CAA80522.1| (Z22935) TAP2B [Homo sapiens]
Length = 703
Score = 221 bits (558), Expect = 1e-56
Identities = 144/551 (26%), Positives = 283/551 (51%), Gaps = 15/551 (2%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
L+ R +K + + L +V + L P+ ID I+ G + F + ++
Sbjct: 137 LMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVID--ILGGDFDPHAFASAIF 194
Query: 69 LLSLVAQWFFTTLQT-----FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+ L + F ++L +T + LR +R QL +L+ +L FF+ TG+L S
Sbjct: 195 FMCLFS--FGSSLSAGCRGGCFTYTMSRINLR-IREQLFSSLLRQDLGFFQETKTGELNS 251
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ +DT ++++ L L S++ + G+ ML + +LTL++L +P + +
Sbjct: 252 RLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYN 311
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+ + RE + +A+ VV E+V G++T+R+FG E+ + + + + Y R +
Sbjct: 312 TRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDL 371
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
++ + + L +++++ G G ++ G +++F+ Y + + +V +Y
Sbjct: 372 ERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYG 431
Query: 304 SLQSALAALERIYEILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEK--GRPVLKDVNL 360
+ S + A E+++ +D + N+ ++ L+G ++F++V F Y RPVLK +
Sbjct: 432 DMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTF 491
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+ P A+VG G+GK+T+A L+ Y PT G++L D + L ++ V Q
Sbjct: 492 TLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQ 551
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
E LF G++ NI +++ V+ + DFI ++ G T GE G L+ G+
Sbjct: 552 EPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQ 611
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++ARA+++DP ++ILDEA S++D + EQ +Q+ + RT ++IAHRL + A
Sbjct: 612 KQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSR--GDRTVLVIAHRLQAVQRA 669
Query: 541 DKVIVVDDGRI 551
+++V+ +G++
Sbjct: 670 HQILVLQEGKL 680
>emb|CAA80523.1| (Z22936) TAP2E [Homo sapiens]
Length = 686
Score = 221 bits (558), Expect = 1e-56
Identities = 144/551 (26%), Positives = 283/551 (51%), Gaps = 15/551 (2%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
L+ R +K + + L +V + L P+ ID I+ G + F + ++
Sbjct: 137 LMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVID--ILGGDFDPHAFASAIF 194
Query: 69 LLSLVAQWFFTTLQT-----FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+ L + F ++L +T + LR +R QL +L+ +L FF+ TG+L S
Sbjct: 195 FMCLFS--FGSSLSAGCRGGCFTYTMSRINLR-IREQLFSSLLRQDLGFFQETKTGELNS 251
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ +DT ++++ L L S++ + G+ ML + +LTL++L +P + +
Sbjct: 252 RLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYN 311
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+ + RE + +A+ VV E+V G++T+R+FG E+ + + + + Y R +
Sbjct: 312 TRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDL 371
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
++ + + L +++++ G G ++ G +++F+ Y + + +V +Y
Sbjct: 372 ERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYG 431
Query: 304 SLQSALAALERIYEILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEK--GRPVLKDVNL 360
+ S + A E+++ +D + N+ ++ L+G ++F++V F Y RPVLK +
Sbjct: 432 DMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTF 491
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+ P A+VG G+GK+T+A L+ Y PT G++L D + L ++ V Q
Sbjct: 492 TLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQ 551
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
E LF G++ NI +++ V+ + DFI ++ G T GE G L+ G+
Sbjct: 552 EPVLFSGSVRNNITYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQ 611
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++ARA+++DP ++ILDEA S++D + EQ +Q+ + RT ++IAHRL + A
Sbjct: 612 KQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSR--GDRTVLVIAHRLQTVQRA 669
Query: 541 DKVIVVDDGRI 551
+++V+ +G++
Sbjct: 670 HQILVLQEGKL 680
>gb|AAF64672.1|AF218367_1 (AF218367) ABC transporter protein [Brucella abortus]
Length = 596
Score = 221 bits (558), Expect = 1e-56
Identities = 165/576 (28%), Positives = 294/576 (50%), Gaps = 25/576 (4%)
Query: 19 SERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLYLLSLVAQWFF 78
S+ L+ +++ ++ + ++ +P +D + + A++ LLSL A
Sbjct: 21 SQPLRLSAMIIGMLLATPPDVLTPLYSGRLVDSLSLGSNAWDAAIHALIALLSLGALALV 80
Query: 79 TTLQTFYTEV--FGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIINDT---NVVN 133
+ + + F K++ ++ + K+ + + D+ G V ++ +++N
Sbjct: 81 SRAGHVFMSLTDFTLKIMSDMAASAFRKLQRFSTDWHANAFAGSTVRKVTRGMWALDLLN 140
Query: 134 DVLVSGLLGGLGSILSLAGIIVAML----LLDVKLTLVTLTSVPLMVIIALYFGGKMRRA 189
D L+ LL S+L L G +V + L+ + + + ++ + ++I+L F + A
Sbjct: 141 DTLIIALLP---SLLMLVGSVVLLAWFWPLMGLMVAIGSVLYIACTIVISLGF---VAPA 194
Query: 190 YRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTE--TIKAYLRVAIYMGI 247
++ + +S++ ++AFG E ++ + V + T A++ ++ G
Sbjct: 195 ATLANSWDTRMGGALADSMSCNAVVKAFGAEAREDERLAMVVNKWRTHTAHMAAGLHAGS 254
Query: 248 FWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRF--RGPINNVVSMYDSL 305
+ + L+ V+IA+ YL +G + G + F + F +G + +V +L
Sbjct: 255 RF-IQGTNLLVMRGVIIAFALYLWTRGQATAGDIT-FRSHRLFFMLQGYLRDVGMHIRNL 312
Query: 306 QSALAALERIYEILDDENVEDYEGISVEKL-KGEIEFRNVWFEYEKGRPVL-KDVNLYIP 363
Q ++ +E + +I + D G ++ GEI F +V F Y + L +D ++ I
Sbjct: 313 QRSVNHMEELVDIEAQLRIADKPGAPAIRIGNGEITFNHVTFHYGRHEAALYRDFSVRIE 372
Query: 364 PASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETY 423
+V + G +G+GKTT LI R YD G IL DG + +++ SLR +I V QE
Sbjct: 373 AGERVGLAG-SGSGKTTFVKLIQRLYDVNGGAILIDGQNIADVTQASLRSQIAIVQQEPI 431
Query: 424 LFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQL 483
LF T+ ENI A P A + ++ + HDFI +LPKGY T GE G L+ GERQ
Sbjct: 432 LFHRTLAENIAYARPGASQAEIEEAARLASAHDFISRLPKGYRTLVGERGVKLTGGERQR 491
Query: 484 ISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKV 543
+++ARA L D I+ILDEA SS+D ++E L+Q+AM +LM GRT+++IAHRLS R D++
Sbjct: 492 VAIARAFLADAPILILDEATSSLDSESEVLIQHAMERLMVGRTTLVIAHRLSTVRALDRL 551
Query: 544 IVVDDGRIVEEGSPGELLSRK-GYFYKLYTSQMQEV 578
+V D GRIVEEG+ L+ + G + +L+ Q E+
Sbjct: 552 LVFDKGRIVEEGNHDALIRKSDGIYRRLFERQALEL 587
>pir||I38528 ABC transport protein - human (fragment) >gi|533092|gb|AAA79901.1|
(U07844) ABC transport protein [Homo sapiens]
Length = 622
Score = 221 bits (557), Expect = 2e-56
Identities = 144/551 (26%), Positives = 282/551 (51%), Gaps = 15/551 (2%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
L+ R +K + + L +V + L P+ ID I+ G + F + ++
Sbjct: 73 LMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVID--ILGGDFDPHAFASAIF 130
Query: 69 LLSLVAQWFFTTLQT-----FYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVS 123
+ L + F ++L +T + LR +R QL +L+ +L FF+ TG+L S
Sbjct: 131 FMCLFS--FGSSLSAGCRGGCFTYTMSRINLR-IREQLFSSLLRQDLGFFQETKTGELNS 187
Query: 124 RIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVIIALYFG 183
R+ +DT ++++ L L S++ + G+ ML + +LTL++L +P + +
Sbjct: 188 RLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYN 247
Query: 184 GKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAI 243
+ + RE + +A+ VV E+V G++T+R+FG E+ + + + + Y R +
Sbjct: 248 TRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDL 307
Query: 244 YMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYD 303
++ + + L +++++ G G ++ G +++F+ Y + + +V +Y
Sbjct: 308 ERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYG 367
Query: 304 SLQSALAALERIYEILDDE-NVEDYEGISVEKLKGEIEFRNVWFEYEK--GRPVLKDVNL 360
+ S + A E+++ +D + N+ ++ L+G ++F++V F Y RPVLK +
Sbjct: 368 DMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTF 427
Query: 361 YIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQ 420
+ P A+VG G+GK+T+A L+ Y PT G++L D + L ++ V Q
Sbjct: 428 TLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQ 487
Query: 421 ETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGE 480
E LF G++ NI +++ V+ + DFI ++ G T GE G L+ G+
Sbjct: 488 EPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQ 547
Query: 481 RQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFA 540
+Q +++ARA+++DP ++ILDEA S++D + EQ +Q+ RT ++IAHRL + A
Sbjct: 548 KQRLAIARALVRDPRVLILDEATSALDVQCEQALQD--WNSCGDRTVLVIAHRLQTVQRA 605
Query: 541 DKVIVVDDGRI 551
+++V+ +G++
Sbjct: 606 HQILVLQEGKL 616
>emb|CAA88940.2| (Z49126) contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=430.2, E-value=6.2e-126, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=141.7, E-value=4.1e-39, N=2 [Caenorhabditis
elegans]
Length = 1239
Score = 221 bits (557), Expect = 2e-56
Identities = 167/599 (27%), Positives = 290/599 (47%), Gaps = 44/599 (7%)
Query: 10 LKRFIKEAL-----SERRTLAIVVVSIVGSALANLASPYILRVA---IDHYIIPGR---- 57
LKR E L +++ L ++ +++ + L P +L + D Y+ G
Sbjct: 53 LKRLESEDLDLINFAKKSDLIFIITALICALLGGTIQPVVLLIGGWITDLYLTNGNTAGN 112
Query: 58 -----------YKELGFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKIL 106
Y LGF ++ +L+L+ Q + ++L ++R + +L
Sbjct: 113 DEFLYSVLTLIYAGLGFGVIILVLALI--------QGVCIQRGTSRILDSIRKEFLGAVL 164
Query: 107 QSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTL 166
+ + ++ S+G + ++ + V++D L + + I+A ++ +LT
Sbjct: 165 RQDANWLDKHSSGSITCQLNENIEVISDGLGNKCCMLVRGFAMFTSSIIACAFINWQLTF 224
Query: 167 VTLTSVPLMVIIALYFGGKMRRAYRETRQKI-AKISSVVEESVAGIETIRAFGKEKDVEK 225
+T T P+ + L+ K+ E + A+ +++EES+ + T+++ + +
Sbjct: 225 ITFTMGPVSAFV-LHLLTKVNEVSNEELMSLSAQSHAIIEESILNVRTVQSCNGQNFMIT 283
Query: 226 EFSKVSTETIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVS----IGVV 281
+ ++V+ + K Y + + G F L + + +G L + + + ++
Sbjct: 284 KLNQVNEKIKKFYNKSTFWAGFFDGLALFVIYFITGISLFFGCRLYFNQEIGKAGDVILI 343
Query: 282 VAFIQYAQRFRGPINNVVSMYDSLQSALAALERIYEILDDE-NVEDYEG-ISVEKLKGEI 339
V I F G + +S SLQ A + +Y+ ++ E EG I + +G I
Sbjct: 344 VNTICVTGYFLGLLGPHMS---SLQQAATSFLLLYKTIESAPKSEGKEGEIKISSTRGNI 400
Query: 340 EFRNVWFEY-EKGRPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILY 398
EFR+V F+Y + VL+ ++L + P VA+VG +G GK+T L+ + Y ++GEIL
Sbjct: 401 EFRDVRFKYFTRDNEVLQGLSLQVLPGQTVALVGTSGCGKSTSIGLLTKLYRASEGEILI 460
Query: 399 DGIDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFI 458
DG + + KSLR++IG V QE LF GTIMENI + EE + FI
Sbjct: 461 DGKNIDMLDAKSLRQQIGIVQQEPKLFDGTIMENIKLGR-NVDEETIKTAADIANASSFI 519
Query: 459 MKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAM 518
KL GYET G G LS G++Q I +ARA++ P I++LDEA S++D E +V A+
Sbjct: 520 EKLENGYETRLGPGGVQLSGGQKQRICIARALVTSPSILLLDEATSALDSHNEHIVNKAL 579
Query: 519 IKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
K EGRT+IIIAHRLS + D++ V+D G+ E G+ EL+ G + +L SQ E
Sbjct: 580 TKASEGRTTIIIAHRLSSLKSVDRIYVLDQGKTKEIGTHDELILLGGIYARLAKSQEVE 638
Score = 198 bits (497), Expect = 2e-49
Identities = 142/504 (28%), Positives = 233/504 (46%), Gaps = 11/504 (2%)
Query: 78 FTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGD--LVSRIINDTNVVNDV 135
F TLQ + +V+ ++ ++ ++L + +F T VSRII+ +
Sbjct: 737 FKTLQMYLCGWLANEVMNEVKQEMLSEVLNKPIPYFDNPETSPSACVSRIISHAHNCYAC 796
Query: 136 LVSGLLGGLGSILSLAGIIVAMLLLDV---KLTLVTLTSVPLMVIIALYFGGKMRRAYRE 192
L + + +AG I ++LL +L ++ L L+ I +L+F RA+ E
Sbjct: 797 LDHR---AIRFVWFIAGTIFSLLLAFPFVWELGVLGLGITILLTIFSLHFVSVAHRAHSE 853
Query: 193 TRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWPLM 252
+ + K E V I I+ E E +FS+ + ++ + + +
Sbjct: 854 -KSVMDKSGEFAVEIVEHIRAIKLLAVEGYFENKFSEYLKTSEIYENKIGFVSSLNFAIT 912
Query: 253 NIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALAAL 312
+++ G L Y G S V AQ + + + A+
Sbjct: 913 QSYVFACDMLLFFVGTLLIYHGRYSPDKVFLAFNGAQMSAWGVMYFSPWFPEIVRGSASA 972
Query: 313 ERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKG--RPVLKDVNLYIPPASKVAI 370
+I+ D G+S ++ G++E +V F Y R V + +L IP +A+
Sbjct: 973 NQIFSFFDKNRTNSTSGLSKPEINGKVEVSDVTFAYPSTPHRNVCEGFSLNIPKGHSIAL 1032
Query: 371 VGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFPGTIM 430
VG +G GK+TI +++ RFY G I D D I LR I V QE LF TI
Sbjct: 1033 VGASGCGKSTIISMLERFYSAKAGRISVDDNDIDGIDVNHLRNNISVVGQEPVLFNATIR 1092
Query: 431 ENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISLARAM 490
ENI + E E+V + CK FI P GY+T GE G LS G++Q I++ARA+
Sbjct: 1093 ENITIGIDEVSVEEVQKACKAANAAGFIESFPLGYDTIVGEGGASLSGGQKQRIAIARAI 1152
Query: 491 LKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVVDDGR 550
++ P I++LDEA S++D ++E++VQ A+ GRTSII+AHRLS + D + + G
Sbjct: 1153 IRKPKILLLDEATSALDTQSEEIVQKALRSATTGRTSIIVAHRLSTVQHCDTIYYISRGA 1212
Query: 551 IVEEGSPGELLSRKGYFYKLYTSQ 574
+ E G+ EL++ + +L +Q
Sbjct: 1213 VAEYGTHAELVAMDSKYARLVAAQ 1236
>emb|CAB97048.1| (AJ272202) mitochondrial half-ABC transporter [Arabidopsis
thaliana]
Length = 728
Score = 220 bits (554), Expect = 4e-56
Identities = 152/512 (29%), Positives = 255/512 (49%), Gaps = 32/512 (6%)
Query: 86 TEVFGQKVLRNLRS---QLHEKILQSNLDFFKTKSTGDLVSRIINDTNVVNDVLVSGLLG 142
T VF + LR +RS ++ + +L + ++ TG L I + +N +L + +
Sbjct: 220 TAVFSKVALRTIRSVSRKVFSHLHDLDLRYHLSRETGGLNRIIDRGSRAINFILSAMVFN 279
Query: 143 GLGSILSLAGII-VAMLLLDVKLTLVTLTSVPLMVIIALYFGGKMRRAYRETRQKIAKIS 201
+ +IL ++ + + +T SV ++ L A + R K +K
Sbjct: 280 VVPTILEISMVSGILAYKFGAAFAWITSLSVGSYIVFTL--------AVTQWRTKFSKAM 331
Query: 202 SVVE--------ESVAGIETIRAF---GKEKDVEKEFSKVSTETIKAYLRVAIYMGIFWP 250
+ + +S+ ET++ F G E + +F K + R ++ F
Sbjct: 332 NKADNDDSTRAIDSLINYETVKYFNNEGYEAEKYDQFLKKYEDAALQTQRSLAFLN-FGQ 390
Query: 251 LMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNVVSMYDSLQSALA 310
+ ++ LS +V+ G + G +++G +V + P+N + S+Y +L
Sbjct: 391 SIIFSTALSTAMVLCSQGIM--NGQMTVGDLVMVNGLLFQLSLPLNFLGSVYRETIQSLV 448
Query: 311 ALERIYEILDDE----NVEDYEGISVEKLKGEIEFRNVWFEYEKGRPVLKDVNLYIPPAS 366
++ ++++L+++ N D + + ++ G IEF NV F Y R +L ++ +P
Sbjct: 449 DMKSMFQLLEEKSDITNTSDAKPLVLKG--GNIEFENVHFSYLPERKILDGISFVVPAGK 506
Query: 367 KVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYVPQETYLFP 426
VAIVG +G+GK+TI ++ RF+D G I DG D K++ SLR IG VPQ+T LF
Sbjct: 507 SVAIVGTSGSGKSTILRMLFRFFDTDSGNIRIDGQDIKEVRLDSLRSSIGVVPQDTVLFN 566
Query: 427 GTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSVGERQLISL 486
TI NI A EE+V + IH+ I P Y T GE G LS GE+Q ++L
Sbjct: 567 DTIFHNIHYGRLSATEEEVYEAARRAAIHETISNFPDKYSTIVGERGLKLSGGEKQRVAL 626
Query: 487 ARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITRFADKVIVV 546
AR LK P I++ DEA S++D TE + NA+ L RTSI IAHRL+ D+++V+
Sbjct: 627 ARTFLKSPAILLCDEATSALDSTTEAEILNALKALASNRTSIFIAHRLTTAMQCDEIVVL 686
Query: 547 DDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
++G++VE+G ELL + G + +L+T Q V
Sbjct: 687 ENGKVVEQGPHDELLGKSGRYAQLWTQQNSSV 718
>pir||T47045 hypothetical protein ybtP [imported] - Yersinia pestis
>gi|4106633|emb|CAA21388.1| (AL031866) ORF 65, len=600
aa, yersiniabactin uptake, ABC Transporter,similar to
many, eg. MTCY02B10_12 M. tuberculosis (859 aa), 35.7%
identity in 577 aa overlap Fasta scores: opt: 1064,
E():0 [Yersinia pestis]
Length = 600
Score = 219 bits (552), Expect = 7e-56
Identities = 152/525 (28%), Positives = 264/525 (49%), Gaps = 19/525 (3%)
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRN-LRSQLHEKILQSNLDFFKTKSTGDLVSRIIN 127
++ V F LQ F T + L N LRS+L K LQ + +G + +++
Sbjct: 70 VIGCVVLTFVLRLQAFNTSHYAAFHLENILRSRLARKALQLPPGVLQQMGSGSVAKVMLD 129
Query: 128 DTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVP---LMVIIALYFGG 184
D ++ + +I+ IV + LD +L + TL + +++++A
Sbjct: 130 DVKSLHIFVADSTPLYARAIIMPLATIVILFWLDWRLAIATLGVLAFGSVVLVLARQRSE 189
Query: 185 KMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTE---TIKAYLRV 241
M + Y + R+++ S+ V E V + +R F + + E +K + R
Sbjct: 190 DMAQRYHKAREQV---SAAVIEFVQAMPVVRTFDSGSTSFLRYQRALEEWVDVLKTWYRK 246
Query: 242 AIYMGIFWPLMNIASLLSVIVVIAYGGY-LAYKGAVSIGVVVAFIQYAQRFRGPINNVVS 300
A + F +I + L + V+ + GY L + G+ VA + + ++
Sbjct: 247 AGFSARF--SFSILNPLPTLFVLIWSGYGLLHYGSFDFIAWVAVLLLGSGMAEAVMPMMM 304
Query: 301 MYDSLQSALAALERIYEILDDENVEDYEGISVEKLKGEIEFRNVWFEYEKGRP--VLKDV 358
+ + + +++RIY++L + + + + I F V F Y + R L++V
Sbjct: 305 LNNLVAQTRLSIQRIYQVLAMPELSLPQS-DQQPQEASITFEQVSFHYPQARTGAALQEV 363
Query: 359 NLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKSLRKRIGYV 418
+ ++P VA+VG +GAGK+T+A L++R+ DP KG I G+D + + +L K++ +V
Sbjct: 364 SFHVPAGQIVALVGPSGAGKSTVARLLLRYADPDKGHIRIGGVDLRDMQTDTLMKQLSFV 423
Query: 419 PQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYETSAGEAGKLLSV 478
Q+ +LF TI NI + P+A E VI + HDFI LP+GY T GE G LS
Sbjct: 424 FQDNFLFADTIANNIRLGAPDAPLEAVIAAARVAQAHDFISALPEGYNTRVGERGVFLSG 483
Query: 479 GERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRTSIIIAHRLSITR 538
G+RQ I++ARA+L+D I++LDEA + DP+ E + A+ M GRT I++AHRLS+
Sbjct: 484 GQRQRITIARALLQDRPILVLDEATAFADPENEAALIKALAAAMRGRTVIMVAHRLSMVT 543
Query: 539 FADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE---VPG 580
AD +++ DG++ E G+ +LL++ G + +L+ Q VPG
Sbjct: 544 QADVILLFSDGQLREMGNHTQLLAQGGLYQRLWQHYQQAQHWVPG 588
>gb|AAA86666.1| (L36248) ATP-binding cassette protein [Fasciola hepatica]
Length = 726
Score = 218 bits (550), Expect = 1e-55
Identities = 166/540 (30%), Positives = 272/540 (49%), Gaps = 40/540 (7%)
Query: 62 GFIAMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKT--KSTG 119
G +A+L L+ L + +T Q ++ V GQ++ + LR L E IL+ L +F G
Sbjct: 204 GIMALLGLIRLAS----STFQAYFFGVAGQRLTKRLRLTLFESILRQELAWFDEPDNQVG 259
Query: 120 DLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMV--- 176
L +R+ D N V+ + S + + S++ L +V + + KLTLV P++
Sbjct: 260 TLTARVAGDANKVHPICGSAMGQIVESVMLLIFSLVVAFVYNWKLTLVVAVFFPVIAFSS 319
Query: 177 ---IIALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTE 233
I L FGG R V E+ + T+ F E ++F+ S +
Sbjct: 320 FINIKQLRFGGDSAGETEAVR--------VAHEAFSAHRTVAGFALEHYFHQQFAHASGQ 371
Query: 234 TIKAYLRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAV---SIGVVVAFIQYAQR 290
+ LR + + + L + S ++G +L +G + +I V A I +A +
Sbjct: 372 QSQLALRASFRHAVVYALAQSLPICSYAAAFSFGAHLMSQGEIKLIAIFRVFAAISFAAQ 431
Query: 291 FRGPINNVVSMYDSLQSALAALERIYEILDDENVEDY-EGISVEKLKGE--IEFRNVWFE 347
G ++ + +++ A AA RI+ I++ + +G+ I FR+V F
Sbjct: 432 ALGRTSH---LGPAMKQAGAAASRIFRIIERSSAMPVSQGVQPNWNLNTVPIHFRHVSFR 488
Query: 348 YEKG--RPVLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFY-----DPTKGEILYDG 400
Y PVL+D + I P VA VG +G GKT++ NL+ RFY D +G I
Sbjct: 489 YPSRPTMPVLRDFSHTICPGETVAFVGHSGCGKTSVLNLLQRFYTIGPCDSNRG-IFVGE 547
Query: 401 IDGKKISRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKE--EDVIRVCKELGIHDFI 458
+++ LR +IG V QE +LF T+ +NI + E + E+V+ + IHDFI
Sbjct: 548 TPLDRLAPCWLRSQIGMVDQEPHLFDITLQKNIAYGDNEREVSMEEVMEAARLAEIHDFI 607
Query: 459 MKLPKGYETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAM 518
+ LP GYE AG G LS GE+Q I++ARA+++ P + +LDEA S++D +TE +Q+ +
Sbjct: 608 VSLPHGYEL-AGPHGCELSGGEKQRIAIARALIRRPHLFLLDEATSALDTQTELRIQSKL 666
Query: 519 IKLMEGRTSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQEV 578
+ + GRT++I AHRL+ T A+ V+V+ DG +E G P EL+ G ++ LY +Q E+
Sbjct: 667 NEALRGRTALISAHRLTATSGAETVVVLADGHKLESGKPDELIQLHGAYHALYHAQANEL 726
>emb|CAA94219.2| (Z70268) Similarity to C.elegans p-glycoprotein (SW:MDR1_CAEEL),
contains similarity to Pfam domain: PF00005 (ABC
transporter), Score=388.5, E-value=2.1e-113, N=2;
PF00664 (ABC transporter transmembrane region.),
Score=191.4, E-value=4.7e-54, N=2 [Caen>
Length = 1269
Score = 218 bits (549), Expect = 2e-55
Identities = 169/591 (28%), Positives = 294/591 (49%), Gaps = 46/591 (7%)
Query: 9 LLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHYIIPGRYKELGFIAMLY 68
L + F+ L E A V+V+I + P L+ A + Y G Y+ + + +
Sbjct: 55 LCQPFVSYTLGET---AQVLVTITNAINNKTIDPADLKKAYEQYE-RGMYQ----VVLYF 106
Query: 69 LLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLDFFKTKSTGDLVSRIIND 128
L A + F ++Q + G +R Q ++L+ + ++F STG L S ++ND
Sbjct: 107 FLCGCAYFTFASIQHAIMKYVGDNTTYRVRKQYISRLLRKDAEYFDNVSTGHL-STVLND 165
Query: 129 TNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVT---LTSVPLMVIIALYFGGK 185
+ ++L ++ ++ L T L S + + + F G
Sbjct: 166 N-------LERFREVFNEKIALIFALLTDFVVGTALAFYTDWRLASYGIFFSLGIAFSGF 218
Query: 186 MRRA-YRETRQK----IAKISSVVEESVAGIETIRAF-GKEKDVEKEFSKVSTETIKAYL 239
+ A +T K A S+ +++ +T+ + G+ ++E+ TE +KA
Sbjct: 219 INSAGVMKTTGKQNTHYANAGSIAFQTLGAYKTVCSLNGQNTEIERY-----TEELKAGE 273
Query: 240 RVAIYMGIFWPLMNIASLL---SVIVVIAY-GGYLAYKGAVSIGVVVAFIQYAQRFRGPI 295
+ I+ + + + + S+ VI Y G + Y G++ VVV Y +
Sbjct: 274 KYGIHRALMYSISRGFTYFFCNSLNTVILYVGANMIYSGSLEPAVVVRIFHYMMFGAFCL 333
Query: 296 NNVVSMYDSLQSALAALERIYEIL--DDENVE----DYEGISVEKLKGEIEFRNVWFEYE 349
+ + L A+++ I E+L +D +E DY+ + VE + G I F+NV F Y
Sbjct: 334 SEALPHISRLAGAISSTAPIAEMLIKEDNVIEKDETDYD-VEVE-VNGNISFKNVKFSYP 391
Query: 350 KGRP---VLKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKI 406
RP VLK ++ + +A+VG +G+GK+T+ L++ +Y+ G I DG+D +
Sbjct: 392 T-RPDAQVLKGISFDVQNGECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGMDLNDM 450
Query: 407 SRKSLRKRIGYVPQETYLFPGTIMENILMANPEAKEEDVIRVCKELGIHDFIMKLPKGYE 466
+ K LR+ IG V QE LF TI ENI NP ++ ++ +DF+ PKG +
Sbjct: 451 NIKRLRRVIGVVSQEPVLFNTTIEENIRFGNPNVSLPEIYGALRKANAYDFVCSFPKGIK 510
Query: 467 TSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGRT 526
T GE G LS G++Q I++AR ++++P I++LDEA S++D ++EQ+VQ A+ +GRT
Sbjct: 511 TIVGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEQVVQKALENASQGRT 570
Query: 527 SIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQMQE 577
+I++AHRLS R A K+IV+ G IVE G+ EL++++G + L +Q+ E
Sbjct: 571 TIVVAHRLSTIRNASKIIVMQKGEIVEVGNHDELIAKRGVYNDLVQAQLLE 621
Score = 181 bits (455), Expect = 2e-44
Identities = 147/589 (24%), Positives = 276/589 (45%), Gaps = 29/589 (4%)
Query: 8 SLLKRFIKEALSERRTLAIVVVSIVGSALANLASPYILRVAIDHY---IIPGRYKELGFI 64
S L+ +K+ R + +++ GSA+ ++ P + ++ + Y + G +++ +
Sbjct: 679 SNLREIVKQC---RPDYCFLFIAVFGSAIQGVSYPILAQLIVRTYEGFAMIG--EDMLYY 733
Query: 65 AMLYLLSLVAQWFFTTLQTFYTEVFGQKVLRNLRSQLHEKILQSNLD----FFK--TKST 118
+ L+ LS + F L + + KV L ++L K L F+ S
Sbjct: 734 SHLWALSFMFLAVFRPLTLYCQYYYFGKVSEQLSTRLRIKSFSHMLSLPCAFYDDPNHSA 793
Query: 119 GDLVSRIINDTNVVNDVLVSGLLGGLGSILSLAGIIVAMLLLDVKLTLVTLTSVPLMVII 178
L +R+ D++ V + L + ++++++ I L K+TL L PL+ +
Sbjct: 794 TRLSNRLNTDSSNVKAAVDDRLGCVIMTVVAISIAITTASLYCWKMTLEVLIFFPLLYLA 853
Query: 179 ALYFGGKMRRAYRETRQKIAKISSVVEESVAGIETIRAFGKEKDVEKEFSKVSTETIKAY 238
+ + +E + E++ + T+RA E + S+ + K+Y
Sbjct: 854 EYCYDAATETSIQEDTIAFENSNRTAIEALENMRTVRALNLEDKIMSLISEHLQKIHKSY 913
Query: 239 LRVAIYMGIFWPLMNIASLLSVIVVIAYGGYLAYKGAVSIGVVVAFIQYAQRFRGPINNV 298
+ AI G L L V +G YLA + V+ ++ +
Sbjct: 914 FKRAIIQGAANGLSLSCYLFVYSVSFKFGTYLALRKEVAPMDTYLILETLSMTANMAGSA 973
Query: 299 VSMYDSLQSALAALERIYEILDDENVEDYEGISVEKL--KGEIEFRNVWFEYEK--GRPV 354
+ + A+ A I+ + + +K KGEI NV F Y++ R +
Sbjct: 974 AAYLPDYKKAVHAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHYDQRPDRMI 1033
Query: 355 LKDVNLYIPPASKVAIVGKTGAGKTTIANLIMRFYDPTKGEILYDGIDGKKISRKS---- 410
L VNL + P +A+VG +G GK+TI +L+ RFY GE++ ID KI ++
Sbjct: 1034 LNGVNLKVDPGKTLALVGPSGCGKSTIISLLERFYHAVDGEVV--SIDAHKIDSENVEDI 1091
Query: 411 ----LRKRIGYVPQETYLFPGTIMENILMANPEAKEE-DVIRVCKELGIHDFIMKLPKGY 465
LR + V QE LF +I EN+L + + ++ + + +F+ + P+G
Sbjct: 1092 NLNHLRSNLALVSQEPTLFNCSIRENLLYGLTRSVPQLELEKALQTANAFNFVFQFPQGL 1151
Query: 466 ETSAGEAGKLLSVGERQLISLARAMLKDPDIVILDEALSSVDPKTEQLVQNAMIKLMEGR 525
+T GE G LS G++Q I++ARA+L++P +++LDEA S++D +E++VQNA+ E
Sbjct: 1152 DTIVGERGAQLSGGQKQRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERL 1211
Query: 526 TSIIIAHRLSITRFADKVIVVDDGRIVEEGSPGELLSRKGYFYKLYTSQ 574
+++++AHRL AD + V+ +G++ E+G+ ELL ++ +++L Q
Sbjct: 1212 STVVVAHRLLTVVNADSIAVLKNGKVAEQGTHEELLRKRSIYWRLVQKQ 1260
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.139 0.383
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 189009857
Number of Sequences: 2977
Number of extensions: 7594943
Number of successful extensions: 37877
Number of sequences better than 1.0e-10: 1843
Number of HSP's better than 0.0 without gapping: 750
Number of HSP's successfully gapped in prelim test: 1095
Number of HSP's that attempted gapping in prelim test: 32118
Number of HSP's gapped (non-prelim): 2455
length of query: 580
length of database: 189,106,746
effective HSP length: 60
effective length of query: 520
effective length of database: 153,197,526
effective search space: 79662713520
effective search space used: 79662713520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 167 (69.5 bits)