BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2154 (HSDR) DE:type I restriction-modification enzyme, R
subunit
(1104 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75221 type I restriction-modification enzyme, r chain PAB2... 2228 0.0
pir||D64315 type I restriction enzyme homolog - Methanococcus ja... 717 0.0
sp|Q57588|Y124_METJA HYPOTHETICAL PROTEIN MJ0124 >gi|2826244|gb|... 674 0.0
sp|Q58611|YC14_METJA HYPOTHETICAL PROTEIN MJ1214 >gi|2826376|gb|... 533 e-150
pir||E64451 type I restriction enzyme homolog - Methanococcus ja... 532 e-150
pir||A69226 type I restriction enzyme - Methanobacterium thermoa... 411 e-113
gi|11499298 type I restriction-modification enzyme, R subunit [A... 388 e-106
gi|10954527 type I restriction enzyme [Methanococcus jannaschii]... 208 4e-52
gb|AAG18735.1| (AE004978) type I restriction modification enzyme... 207 5e-52
pir||A82522 type I restriction-modification system endonuclease ... 206 1e-51
pir||F64114 type I site-specific deoxyribonuclease (EC 3.1.21.3)... 187 4e-46
pir||C81302 probable type I site-specific deoxyribonuclease (EC ... 184 5e-45
pir||JC5216 type I site-specific deoxyribonuclease (EC 3.1.21.3)... 180 8e-44
pir||B64695 type I restriction enzyme R protein - Helicobacter p... 165 2e-39
pir||C71808 type I restriction enzyme (restriction chain) - Heli... 157 5e-37
emb|CAA68059.1| (X99719) Sty SBLI [Salmonella enterica] 153 1e-35
pir||S49394 HsdR1 protein - Mycoplasma pulmonis >gi|496157|gb|AA... 152 3e-35
pir||T30329 hsdR protein - Klebsiella pneumoniae >gi|2411488|gb|... 150 6e-35
gb|AAC25971.1| (AF003541) endonuclease (R) subunit homolog [Myco... 147 7e-34
pir||C81153 type I restriction enzyme EcoR124II R protein, proba... 127 9e-28
sp|P10486|T1R1_ECOLI TYPE I RESTRICTION ENZYME ECOR124II R PROTE... 125 3e-27
gi|10956196 type IC restriction subunit [Streptococcus thermophi... 122 3e-26
pir||T09459 type I site-specific deoxyribonuclease (EC 3.1.21.3)... 121 4e-26
gb|AAF69137.1|AF228680_1 (AF228680) HsdR [Lactococcus lactis] >g... 121 4e-26
pir||T30322 type I site-specific deoxyribonuclease (EC 3.1.21.3)... 116 1e-24
pir||B71890 type I restriction enzyme (restriction chain) - Heli... 112 3e-23
pir||F82522 type I restriction-modification system endonuclease ... 111 4e-23
pir||H82934 type I restriction enzyme R protein UU095 [imported]... 108 3e-22
pir||F64625 type I restriction enzyme R protein - Helicobacter p... 108 3e-22
gb|AAG22017.1|AF288038_2 (AF288038) putative HsdR [Streptococcus... 96 2e-18
>pir||B75221 type I restriction-modification enzyme, r chain PAB2154 - Pyrococcus
abyssi (strain Orsay) >gi|5457726|emb|CAB49217.1|
(AJ248283) type I restriction-modification enzyme, R
subunit [Pyrococcus abyssi]
Length = 1104
Score = 2228 bits (5710), Expect = 0.0
Identities = 1104/1104 (100%), Positives = 1104/1104 (100%)
Query: 1 MALIPESAVHREIKENLLRIGWEDGNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLERKI 60
MALIPESAVHREIKENLLRIGWEDGNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLERKI
Sbjct: 1 MALIPESAVHREIKENLLRIGWEDGNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLERKI 60
Query: 61 RELNRAFFDNLTEEEEEKVWGEIRSKLASSGEVEMLEYIKYGVPITVLGRHDKVILIDYD 120
RELNRAFFDNLTEEEEEKVWGEIRSKLASSGEVEMLEYIKYGVPITVLGRHDKVILIDYD
Sbjct: 61 RELNRAFFDNLTEEEEEKVWGEIRSKLASSGEVEMLEYIKYGVPITVLGRHDKVILIDYD 120
Query: 121 DPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVH 180
DPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVH
Sbjct: 121 DPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVH 180
Query: 181 GTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSGDAPASEWRYPNEDKP 240
GTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSGDAPASEWRYPNEDKP
Sbjct: 181 GTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSGDAPASEWRYPNEDKP 240
Query: 241 DIFDLLKPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKN 300
DIFDLLKPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKN
Sbjct: 241 DIFDLLKPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKN 300
Query: 301 GLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFER 360
GLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFER
Sbjct: 301 GLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFER 360
Query: 361 HFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKF 420
HFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKF
Sbjct: 361 HFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKF 420
Query: 421 EAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAY 480
EAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAY
Sbjct: 421 EAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAY 480
Query: 481 PKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVE 540
PKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVE
Sbjct: 481 PKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVE 540
Query: 541 AFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVA 600
AFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVA
Sbjct: 541 AFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVA 600
Query: 601 VNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHN 660
VNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHN
Sbjct: 601 VNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHN 660
Query: 661 ETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILR 720
ETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILR
Sbjct: 661 ETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILR 720
Query: 721 VMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIYEMLARQDPKVL 780
VMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIYEMLARQDPKVL
Sbjct: 721 VMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIYEMLARQDPKVL 780
Query: 781 EDFKRNFARSIDEKVEEFENKLQKVKEDLSRIGIEVDILKAFKKQGRWKELEAEMDRVRN 840
EDFKRNFARSIDEKVEEFENKLQKVKEDLSRIGIEVDILKAFKKQGRWKELEAEMDRVRN
Sbjct: 781 EDFKRNFARSIDEKVEEFENKLQKVKEDLSRIGIEVDILKAFKKQGRWKELEAEMDRVRN 840
Query: 841 ILAPIALDFKGNEPKAVRLFNDLHEVISMYRSLGAHPAKLAYIDDMIVVGAIYSTFIRLI 900
ILAPIALDFKGNEPKAVRLFNDLHEVISMYRSLGAHPAKLAYIDDMIVVGAIYSTFIRLI
Sbjct: 841 ILAPIALDFKGNEPKAVRLFNDLHEVISMYRSLGAHPAKLAYIDDMIVVGAIYSTFIRLI 900
Query: 901 DFSRKKSKFWDDLLRFVHEHMEVGPMRELIKVKLSEFSGGEASFEVVARFYKLYYTAEDN 960
DFSRKKSKFWDDLLRFVHEHMEVGPMRELIKVKLSEFSGGEASFEVVARFYKLYYTAEDN
Sbjct: 901 DFSRKKSKFWDDLLRFVHEHMEVGPMRELIKVKLSEFSGGEASFEVVARFYKLYYTAEDN 960
Query: 961 IHDPFYKAILERLNRLLEEWINRNIDLKALRKQINILEGQIGEYEKKRAGKTWQESLLES 1020
IHDPFYKAILERLNRLLEEWINRNIDLKALRKQINILEGQIGEYEKKRAGKTWQESLLES
Sbjct: 961 IHDPFYKAILERLNRLLEEWINRNIDLKALRKQINILEGQIGEYEKKRAGKTWQESLLES 1020
Query: 1021 VKFYVKNYLGLEGVEFKKFQRELKRLRRLNPRTVKRLSSSLLDDIMEAIKDDNLNKYREL 1080
VKFYVKNYLGLEGVEFKKFQRELKRLRRLNPRTVKRLSSSLLDDIMEAIKDDNLNKYREL
Sbjct: 1021 VKFYVKNYLGLEGVEFKKFQRELKRLRRLNPRTVKRLSSSLLDDIMEAIKDDNLNKYREL 1080
Query: 1081 SKEIDRLVEESIIPEVRKHVRGSA 1104
SKEIDRLVEESIIPEVRKHVRGSA
Sbjct: 1081 SKEIDRLVEESIIPEVRKHVRGSA 1104
>pir||D64315 type I restriction enzyme homolog - Methanococcus jannaschii
Length = 1163
Score = 717 bits (1830), Expect = 0.0
Identities = 458/1212 (37%), Positives = 674/1212 (54%), Gaps = 200/1212 (16%)
Query: 13 IKENLLRIGWEDGNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLERKIRELNRAFFDNLT 72
IKE L IGWEDG + +E++ + D+ N E K +E+N+ LT
Sbjct: 16 IKEKLQEIGWEDGKKYINFKEYQXIP----------DYYXPNFFEEKFKEINKTLLSYLT 65
Query: 73 EEEEEKVWGEIRSKLASSGEVEMLEYIKYGVPITVL-GRHDKVILIDYDDPTNNIFFFLH 131
+E ++V I+++L ++ E+++L+Y+KYG+ + V K LIDY + N FF+L
Sbjct: 66 PKEVKEVIDFIKNELKNADEIKILDYLKYGIEVVVKKSEKRKFKLIDYKNIDKNTFFYLC 125
Query: 132 EAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIR 191
EA++ G P+N +PD +LFINGIP+VIIEAKA I+ + E ++QIR
Sbjct: 126 EAEFKGNPKNSRPDITLFINGIPVVIIEAKATLKID--------------SHLEGISQIR 171
Query: 192 KYERYSKPLFRFVQFGVAYGDKQLYTPTMP---RDSGDAPASEWRYPNED------KPDI 242
+YE++S LFRFVQF ++YG++QLYTPTMP +++ PA WR + K DI
Sbjct: 172 RYEKFSPDLFRFVQFAISYGEEQLYTPTMPNWYKENIHLPAYYWRIRQKINGKKVVKDDI 231
Query: 243 FDLLKPERLLDMLRHYTFF----FKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEK 298
F +L P LL+++R++ F+ + K K+IAR+NQY A KK +KRI++YLS +S+
Sbjct: 232 FYILNPSILLEIIRYFIFYRKDEYSKTKTLSKIIARYNQYFATKKAMKRIDEYLSGDSKN 291
Query: 299 KNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLE--------------- 343
K GLIW WQGSGKT+ MFF+AN+FL++Y NP++FF+VDR+DLE
Sbjct: 292 K-GLIWHWQGSGKTYTMFFIANYFLDKYFSENPVIFFVVDRVDLERQSKEFYEAIQEKKF 350
Query: 344 -------DQHSNIFE----------------------SVEDREFERH------------- 361
D + ++E +++ ++ER
Sbjct: 351 KTILKRIDSINKLYEVIKSIKMSELSNKVIVRGIYTTTIQKFQYERSKKEKDNNKEKDKD 410
Query: 362 ---FDRIRSISELRKRIEEIIESEET-GRI--------IPTGLYITTIQKFQYDKFKDMV 409
D + I E+ K+IE+ ++ EE G+I I +Y+ +++ +++K +
Sbjct: 411 DEDLDLSKPIEEIIKKIEDKLKKEEKEGKIKGLKDLLIILAFIYLKHLKEKNPEEYKKHI 470
Query: 410 R-VRKVKGEEKFEAEKA----VKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTG 464
++K+K ++K E +K+ IL LIDEAHRTQYG L + + FP + FGFTG
Sbjct: 471 ENLKKLKDKDKKEEYLINLGNIKRKHILILIDEAHRTQYGILGGMRKITFPNAITFGFTG 530
Query: 465 TPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEE-----EGVSIAL 519
TP+FK ++NTF EF+YP+ GE++LDVYFI DSI+D FTL + +++++E EG+ I L
Sbjct: 531 TPVFKNEKNTFTEFSYPEKGEFYLDVYFIGDSIKDKFTLPLTYQIVKEGDIKSEGIQITL 590
Query: 520 DESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAE 579
DE +K FID + + ED+ F RKK L + + KS+ L +PK I++ A+
Sbjct: 591 DEEDIKEFIDEW-IKRGEDINLF--DRKK--------LPKYINKSKTILLNPKRIDKVAK 639
Query: 580 YIAKRIYDDTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKH 639
YI RI +DT F FKAMVVAVNR CV FKKALD KE F +
Sbjct: 640 YIVDRIEEDTENFKFKAMVVAVNRLGCVRFKKALDKYLKEKFGDE--------------- 684
Query: 640 FRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKD 699
AE+ +EVVMTY HNE + I E+ K LK R D++ IN++I E F +
Sbjct: 685 -------AEKWAEVVMTYHHNEEEKEIIEYMKKLKKERN--SNDFNEINQIIREEFLNSE 735
Query: 700 YPKVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLL 759
PK+LIVTDMLLTGFDAP L+VMYL KP++ HRLLQA+ R NRPYP+KE GL+VD VGL
Sbjct: 736 NPKILIVTDMLLTGFDAPRLKVMYLDKPLYGHRLLQAIARTNRPYPDKEFGLIVDSVGLF 795
Query: 760 PAVIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSR-------I 812
+ +Y MLA ++ + EDFK N SIDE +EF+ KL+ VKE L +
Sbjct: 796 KVLTETMALYNMLAEEE--IREDFKNNLISSIDEIFQEFKLKLEMVKESLKNLKINDEDL 853
Query: 813 GIEVDILKAFKKQGRW--KELEAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVISMY 870
I+V+ LK K + EL+ ++D ++A A D G + ++L +DL VI +Y
Sbjct: 854 SIDVNTLKTLTKNKDFNNNELKEKLD----LIAFYAED--GKNARILKLIDDLKAVIKLY 907
Query: 871 RSLGAHPAKLAYIDDMIVVGAIYSTFIRLIDFSRKKS-KFWDDLLRFVHEHMEVGPMREL 929
++LG++P K+ YI+D+ ++ IY+ I+ + +K + KFW++L+ F+H M V + +
Sbjct: 908 KALGSYPQKIFYIEDIELLSFIYAYLIKKLKPKKKSNRKFWEELISFIHNKMLVDDLTVI 967
Query: 930 IKVKLS---------EFSGGEASFEVVARFY-KLYYTAEDNIHDPFYKAILERLNRLLEE 979
++ L+ E G VA +Y L + D HDP YK ILERL RL +
Sbjct: 968 EEINLNPDDLDKILKENIGKREIKRAVANYYFILKNSILDKQHDPIYKEILERLERLRRD 1027
Query: 980 WINRNIDLKALRKQINILEGQIGEYEKKRAGKTWQESLLESVKFYVKN--------YLGL 1031
WI + ID K I L Y+KK GK+ E + ES+ Y+ L L
Sbjct: 1028 WIMKRIDDKIYLNAIKNLMELKNNYDKKIKGKSSIERIKESISTYIGENILKDQDIKLNL 1087
Query: 1032 EGVE--FKKFQRELKRLRRLNPRTVKR-LSSSLLDDIME----AIKDDNLNKYRELSKEI 1084
E E K Q L +L +L + K+ LS +LL+D+++ IKD++ K ELS
Sbjct: 1088 ENTEKLITKMQ-NLNKLSKLQRKKFKKELSCALLEDLLKELKGKIKDEDAKKVAELS--- 1143
Query: 1085 DRLVEESIIPEV 1096
D LV E I+ E+
Sbjct: 1144 DNLVSEFILKEI 1155
>sp|Q57588|Y124_METJA HYPOTHETICAL PROTEIN MJ0124 >gi|2826244|gb|AAB98104.1| (U67469) type
I restriction-modification enzyme 2, R subunit
[Methanococcus jannaschii]
Length = 1075
Score = 674 bits (1719), Expect = 0.0
Identities = 433/1129 (38%), Positives = 630/1129 (55%), Gaps = 190/1129 (16%)
Query: 96 LEYIKYGVPITVL-GRHDKVILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIP 154
++Y+KYG+ + V K LIDY + N FF+L EA++ G P+N +PD +LFINGIP
Sbjct: 1 MDYLKYGIEVVVKKSEKRKFKLIDYKNIDKNTFFYLCEAEFKGNPKNSRPDITLFINGIP 60
Query: 155 IVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQ 214
+VIIEAKA I+ + E ++QIR+YE++S LFRFVQF ++YG++Q
Sbjct: 61 VVIIEAKATLKID--------------SHLEGISQIRRYEKFSPDLFRFVQFAISYGEEQ 106
Query: 215 LYTPTMP---RDSGDAPASEWRYPNED------KPDIFDLLKPERLLDMLRHYTFF---- 261
LYTPTMP +++ PA WR + K DIF +L P LL+++R++ F+
Sbjct: 107 LYTPTMPNWYKENIHLPAYYWRIRQKINGKKVVKDDIFYILNPSILLEIIRYFIFYRKDE 166
Query: 262 FKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTFIMFFVANW 321
+ K K+IAR+NQY A KK +KRI++YLS +S+ K GLIW WQGSGKT+ MFF+AN+
Sbjct: 167 YSKTKTLSKIIARYNQYFATKKAMKRIDEYLSGDSKNK-GLIWHWQGSGKTYTMFFIANY 225
Query: 322 FLNRYKKRNPIVFFIVDRIDLE----------------------DQHSNIFE-------- 351
FL++Y NP++FF+VDR+DLE D + ++E
Sbjct: 226 FLDKYFSENPVIFFVVDRVDLERQSKEFYEAIQEKKFKTILKRIDSINKLYEVIKSIKMS 285
Query: 352 --------------SVEDREFERH----------------FDRIRSISELRKRIEEIIES 381
+++ ++ER D + I E+ K+IE+ ++
Sbjct: 286 ELSNKVIVRGIYTTTIQKFQYERSKKEKDNNKEKDKDDEDLDLSKPIEEIIKKIEDKLKK 345
Query: 382 EET-GRI--------IPTGLYITTIQKFQYDKFKDMVR-VRKVKGEEKFEAEKA----VK 427
EE G+I I +Y+ +++ +++K + ++K+K ++K E +K
Sbjct: 346 EEKEGKIKGLKDLLIILAFIYLKHLKEKNPEEYKKHIENLKKLKDKDKKEEYLINLGNIK 405
Query: 428 KPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYF 487
+ IL LIDEAHRTQYG L + + FP + FGFTGTP+FK ++NTF EF+YP+ GE++
Sbjct: 406 RKHILILIDEAHRTQYGILGGMRKITFPNAITFGFTGTPVFKNEKNTFTEFSYPEKGEFY 465
Query: 488 LDVYFISDSIRDGFTLDIVHEVIEE-----EGVSIALDESKLKAFIDAYQLNDPEDVEAF 542
LDVYFI DSI+D FTL + +++++E EG+ I LDE +K FID + + ED+ F
Sbjct: 466 LDVYFIGDSIKDKFTLPLTYQIVKEGDIKSEGIQITLDEEDIKEFIDEW-IKRGEDINLF 524
Query: 543 LMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVAVN 602
RKK L + + KS+ L +PK I++ A+YI RI +DT F FKAMVVAVN
Sbjct: 525 --DRKK--------LPKYINKSKTILLNPKRIDKVAKYIVDRIEEDTENFKFKAMVVAVN 574
Query: 603 REACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHNET 662
R CV FKKALD KE F + AE+ +EVVMTY HNE
Sbjct: 575 RLGCVRFKKALDKYLKEKFGDE----------------------AEKWAEVVMTYHHNEE 612
Query: 663 SEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILRVM 722
+ I E+ K LK R D++ IN++I E F + PK+LIVTDMLLTGFDAP L+VM
Sbjct: 613 EKEIIEYMKKLKKERN--SNDFNEINQIIREEFLNSENPKILIVTDMLLTGFDAPRLKVM 670
Query: 723 YLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIYEMLARQDPKVLED 782
YL KP++ HRLLQA+ R NRPYP+KE GL+VD VGL + +Y MLA ++ + ED
Sbjct: 671 YLDKPLYGHRLLQAIARTNRPYPDKEFGLIVDSVGLFKVLTETMALYNMLAEEE--IRED 728
Query: 783 FKRNFARSIDEKVEEFENKLQKVKEDLSR-------IGIEVDILKAFKKQGRW--KELEA 833
FK N SIDE +EF+ KL+ VKE L + I+V+ LK K + EL+
Sbjct: 729 FKNNLISSIDEIFQEFKLKLEMVKESLKNLKINDEDLSIDVNTLKTLTKNKDFNNNELKE 788
Query: 834 EMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVISMYRSLGAHPAKLAYIDDMIVVGAIY 893
++D ++A A D G + ++L +DL VI +Y++LG++P K+ YI+D+ ++ IY
Sbjct: 789 KLD----LIAFYAED--GKNARILKLIDDLKAVIKLYKALGSYPQKIFYIEDIELLSFIY 842
Query: 894 STFIRLIDFSRKKS-KFWDDLLRFVHEHMEVGPMRELIKVKLS---------EFSGGEAS 943
+ I+ + +K + KFW++L+ F+H M V + + ++ L+ E G
Sbjct: 843 AYLIKKLKPKKKSNRKFWEELISFIHNKMLVDDLTVIEEINLNPDDLDKILKENIGKREI 902
Query: 944 FEVVARFY-KLYYTAEDNIHDPFYKAILERLNRLLEEWINRNIDLKALRKQINILEGQIG 1002
VA +Y L + D HDP YK ILERL RL +WI + ID K I L
Sbjct: 903 KRAVANYYFILKNSILDKQHDPIYKEILERLERLRRDWIMKRIDDKIYLNAIKNLMELKN 962
Query: 1003 EYEKKRAGKTWQESLLESVKFYVKN--------YLGLEGVE--FKKFQRELKRLRRLNPR 1052
Y+KK GK+ E + ES+ Y+ L LE E K Q L +L +L +
Sbjct: 963 NYDKKIKGKSSIERIKESISTYIGENILKDQDIKLNLENTEKLITKMQ-NLNKLSKLQRK 1021
Query: 1053 TVKR-LSSSLLDDIME----AIKDDNLNKYRELSKEIDRLVEESIIPEV 1096
K+ LS +LL+D+++ IKD++ K ELS D LV E I+ E+
Sbjct: 1022 KFKKELSCALLEDLLKELKGKIKDEDAKKVAELS---DNLVSEFILKEI 1067
>sp|Q58611|YC14_METJA HYPOTHETICAL PROTEIN MJ1214 >gi|2826376|gb|AAB99215.1| (U67562) type
I restriction-modification enzyme 1, R subunit
[Methanococcus jannaschii]
Length = 1018
Score = 533 bits (1359), Expect = e-150
Identities = 372/1117 (33%), Positives = 603/1117 (53%), Gaps = 133/1117 (11%)
Query: 4 IPESAVHREIKENLLRIGWEDGNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLERKIREL 63
IPE VH +I+ENL ++GW++ + Y G ++ ++++ +LE +++ +
Sbjct: 6 IPEIYVHNDIEENLNKLGWKE------------LEGYEG--EAFSNYIIKPILEEQLKII 51
Query: 64 NRAFFDNLTEEEEEKVWGEIRSKLASSGEVEMLEYIKYGVPITV-LGRH----DKVILID 118
N D++ E ++E + I + E+L+YIK G+ IT+ GR ++V LID
Sbjct: 52 N----DHIGEYKDEFIEKAINKLINEPKPEEILDYIKNGILITLDKGRKGQVSNRVKLID 107
Query: 119 YDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSK 178
Y + NIF + HE K+ G +NI PDF+LFINGIPI+IIEAK E E +
Sbjct: 108 YKNIEKNIFNYAHELKFKG-NDNIIPDFTLFINGIPIIIIEAKR----EFSEKE------ 156
Query: 179 VHGTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSG-DAPASEWRYPNE 237
T EEA+ QI +YER + LF +VQF + YGD++LY PT P + D +++ NE
Sbjct: 157 ---TYEEAINQINRYEREAPKLFNYVQFAIVYGDEKLYIPTYPNEEKEDRFKKPYKWKNE 213
Query: 238 DKP-DIFDLLKPERLLDMLRHYTFFFKKNDGR-IKVIARWNQYRAAKKIIKRIEKYLSRE 295
K DI+DLLK ER+LD ++++ FF K GR K+I R+ QY A KK +RI YL+ +
Sbjct: 214 KKEEDIWDLLKRERVLDTIKNFIFFSKDRAGRKTKIIPRYMQYWAVKKAYERITNYLNNK 273
Query: 296 SEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVED 355
K GL+W WQGSGKTF + ++A F N +K ++PIVF +VDR +LE Q ++ ++++
Sbjct: 274 DYKNRGLVWHWQGSGKTFEILYLAELFYNEFKNKDPIVFIMVDRRELETQFNDDIIALQN 333
Query: 356 REFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVK 415
F+ F +I S+ EL+ +E+I ESE I G+Y+ + KF +K KD +
Sbjct: 334 ANFKDCFKKINSVEELKGVLEDIKESENNPNISEKGVYLVMMHKFDKNKLKDFI------ 387
Query: 416 GEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTF 475
E+ ++ K EIL L DEAHRT+ G+ A + + + GFTGTP+ K+D +TF
Sbjct: 388 -----ESFGSIDKKEILILRDEAHRTESGKFATLRNKILKNAIAIGFTGTPVHKKDMSTF 442
Query: 476 QEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLND 535
+E+AYP++GE++LD +FI +SI++GFTL ++ V++ E + + E ++K I+ + D
Sbjct: 443 KEYAYPQEGEFYLDRFFIEESIKEGFTLPLIWRVVKPEDIK-DISEEEIKNIIEKLFV-D 500
Query: 536 PEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFK 595
ED + K+ +S +E+AE+++ S + L+S I+ ++YIA+ I +DT F FK
Sbjct: 501 EEDAD--------KIVVSKKEIAEKIKLSDL-LKSESSIKEASKYIAEHILEDTENFKFK 551
Query: 596 AMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVM 655
AMVVA +R++C+ FKK LD EY KI+ E ++VV+
Sbjct: 552 AMVVAQDRKSCILFKKYLD----EYLKEKIKNYN------------------ENWTQVVI 589
Query: 656 TYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFD 715
TY HN+ E IE +KK ++ + K+ D +N+ E F K+ PK+LIV LLTGFD
Sbjct: 590 TYIHNDDVE-IENYKKEIEKK---YGKNVDELNKKWTEDFINKENPKILIVNKKLLTGFD 645
Query: 716 APILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLL----PAVIRVKNIYEM 771
APIL+ +Y+++ + ++ LLQA R NRP NK+ GL+VD G+L I N+Y
Sbjct: 646 APILKTIYIHQFLKDYLLLQASARANRPAKNKKYGLIVDLTGILIENYKKAIENYNLY-- 703
Query: 772 LARQDPKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSRI-GIEV-DILKAFKKQGRWK 829
+D + +D N + E F KL + KE I GIE D + KKQ K
Sbjct: 704 ---RDEAINKDILNNLFVETSKIWESFLTKLNEFKELFKLIVGIEFDDFIVNLKKQKNSK 760
Query: 830 ELEAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVISMYRSLGAHPAKLAYIDD---M 886
E + I++ I L K + + L E+I ++ ++GA+ KL Y + +
Sbjct: 761 EF-------KKIISKIILSDKFD-----YFYAKLRELIQLFEAVGAYGEKLNYYETYEWL 808
Query: 887 IVVGAIYSTFIRLIDFSRKKSKFWDDLLRFVHEHMEVGPMRELIKVKLSEFSGGEASFEV 946
++ A + +R + ++ ++++++ I +L E + V
Sbjct: 809 KIISAGINKQMRPKSYKIPYNQIKKEVIKYLEFDTYADIASTSINPQLLENLKNKDEINV 868
Query: 947 VARFYKLYYTAE--DNIHDPFYKAILERLNRLLEEWINRNIDLK-ALRKQINILEGQIGE 1003
+ +YY + N +P Y+ I +R+N L +I++ + + + IN L +
Sbjct: 869 IVA-DMIYYALDTLQNKKEPIYRMIYDRINELKNAYISKTKKNEYVINELINCLNA-LKT 926
Query: 1004 YEKKRAGKTWQESLLESVKFYVKNYLGLEGVEFKKF---QRELKRL---RRLNPRTVKRL 1057
YE++ + E ++++ FY+KN +E KK ++ LK L + + P ++
Sbjct: 927 YEEEEKTLSKSEKAIKNMLFYLKN---VENCNIKKLPLTEKTLKNLEDKKLIKPSDFDKI 983
Query: 1058 SSSLLDDIMEAIKDDNLNKYRELSKEIDRLVEESIIP 1094
L D+ AIK+ K R++S +++VEE I P
Sbjct: 984 KKFLFVDLKNAIKE--TEKRRKVS---NKIVEEIIKP 1015
>pir||E64451 type I restriction enzyme homolog - Methanococcus jannaschii
Length = 1018
Score = 532 bits (1356), Expect = e-150
Identities = 372/1117 (33%), Positives = 602/1117 (53%), Gaps = 133/1117 (11%)
Query: 4 IPESAVHREIKENLLRIGWEDGNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLERKIREL 63
IPE VH +I+ENL +GW++ + Y G ++ ++++ +LE +++ +
Sbjct: 6 IPEIYVHNDIEENLNXLGWKE------------LEGYEG--EAFSNYIIKPILEEQLKII 51
Query: 64 NRAFFDNLTEEEEEKVWGEIRSKLASSGEVEMLEYIKYGVPITV-LGRH----DKVILID 118
N D++ E ++E + I + E+L+YIK G+ IT+ GR ++V LID
Sbjct: 52 N----DHIGEYKDEFIEKAINKLINXPKPEEILDYIKNGILITLDKGRKGQVSNRVKLID 107
Query: 119 YDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSK 178
Y + NIF + HE K+ G +NI PDF+LFINGIPI+IIEAK E E +
Sbjct: 108 YKNIEKNIFNYAHELKFKG-NDNIIPDFTLFINGIPIIIIEAKR----EFSEKE------ 156
Query: 179 VHGTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSG-DAPASEWRYPNE 237
T EEA+ QI +YER + LF +VQF + YGD++LY PT P + D +++ NE
Sbjct: 157 ---TYEEAINQINRYEREAPKLFNYVQFAIVYGDEKLYIPTYPNEEKEDRFKKPYKWKNE 213
Query: 238 DKP-DIFDLLKPERLLDMLRHYTFFFKKNDGR-IKVIARWNQYRAAKKIIKRIEKYLSRE 295
K DI+DLLK ER+LD ++++ FF K GR K+I R+ QY A KK +RI YL+ +
Sbjct: 214 KKEEDIWDLLKRERVLDTIKNFIFFSKDRAGRKTKIIPRYMQYWAVKKAYERITNYLNNK 273
Query: 296 SEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVED 355
K GL+W WQGSGKTF + ++A F N +K ++PIVF +VDR +LE Q ++ ++++
Sbjct: 274 DYKNRGLVWHWQGSGKTFEILYLAELFYNEFKNKDPIVFIMVDRRELETQFNDDIIALQN 333
Query: 356 REFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVK 415
F+ F +I S+ EL+ +E+I ESE I G+Y+ + KF +K KD +
Sbjct: 334 ANFKDCFKKINSVEELKGVLEDIKESENNPNISEKGVYLVMMHKFDKNKLKDFI------ 387
Query: 416 GEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTF 475
E+ ++ K EIL L DEAHRT+ G+ A + + + GFTGTP+ K+D +TF
Sbjct: 388 -----ESFGSIDKKEILILRDEAHRTESGKFATLRNKILKNAIAIGFTGTPVHKKDMSTF 442
Query: 476 QEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLND 535
+E+AYP++GE++LD +FI +SI++GFTL ++ V++ E + + E ++K I+ + D
Sbjct: 443 KEYAYPQEGEFYLDRFFIEESIKEGFTLPLIWRVVKPEDIK-DISEEEIKNIIEKLFV-D 500
Query: 536 PEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFK 595
ED + K+ +S +E+AE+++ S + L+S I+ ++YIA+ I +DT F FK
Sbjct: 501 EEDAD--------KIVVSKKEIAEKIKLSDL-LKSESSIKEASKYIAEHILEDTENFKFK 551
Query: 596 AMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVM 655
AMVVA +R++C+ FKK LD EY KI+ E ++VV+
Sbjct: 552 AMVVAQDRKSCILFKKYLD----EYLKEKIKNYN------------------ENWTQVVI 589
Query: 656 TYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFD 715
TY HN+ E IE +KK ++ + K+ D +N+ E F K+ PK+LIV LLTGFD
Sbjct: 590 TYIHNDDVE-IENYKKEIEKK---YGKNVDELNKKWTEDFINKENPKILIVNKKLLTGFD 645
Query: 716 APILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLL----PAVIRVKNIYEM 771
APIL+ +Y+++ + ++ LLQA R NRP NK+ GL+VD G+L I N+Y
Sbjct: 646 APILKTIYIHQFLKDYLLLQASARANRPAKNKKYGLIVDLTGILIENYKKAIENYNLY-- 703
Query: 772 LARQDPKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSRI-GIEV-DILKAFKKQGRWK 829
+D + +D N + E F KL + KE I GIE D + KKQ K
Sbjct: 704 ---RDEAINKDILNNLFVETSKIWESFLTKLNEFKELFKLIVGIEFDDFIVNLKKQKNSK 760
Query: 830 ELEAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVISMYRSLGAHPAKLAYIDD---M 886
E + I++ I L K + + L E+I ++ ++GA+ KL Y + +
Sbjct: 761 EF-------KKIISKIILSDKFD-----YFYAKLRELIQLFEAVGAYGEKLNYYETYEWL 808
Query: 887 IVVGAIYSTFIRLIDFSRKKSKFWDDLLRFVHEHMEVGPMRELIKVKLSEFSGGEASFEV 946
++ A + +R + ++ ++++++ I +L E + V
Sbjct: 809 KIISAGINKQMRPKSYKIPYNQIKKEVIKYLEFDTYADIASTSINPQLLENLKNKDEINV 868
Query: 947 VARFYKLYYTAE--DNIHDPFYKAILERLNRLLEEWINRNIDLK-ALRKQINILEGQIGE 1003
+ +YY + N +P Y+ I +R+N L +I++ + + + IN L +
Sbjct: 869 IVA-DMIYYALDTLQNKKEPIYRMIYDRINELKNAYISKTKKNEYVINELINCLNA-LKT 926
Query: 1004 YEKKRAGKTWQESLLESVKFYVKNYLGLEGVEFKKF---QRELKRL---RRLNPRTVKRL 1057
YE++ + E ++++ FY+KN +E KK ++ LK L + + P ++
Sbjct: 927 YEEEEKTLSKSEKAIKNMLFYLKN---VENCNIKKLPLTEKTLKNLEDKKLIKPSDFDKI 983
Query: 1058 SSSLLDDIMEAIKDDNLNKYRELSKEIDRLVEESIIP 1094
L D+ AIK+ K R++S +++VEE I P
Sbjct: 984 KKFLFVDLKNAIKE--TEKRRKVS---NKIVEEIIKP 1015
>pir||A69226 type I restriction enzyme - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622038|gb|AAB85438.1| (AE000868)
type I restriction enzyme [Methanobacterium
thermoautotrophicum]
Length = 1013
Score = 411 bits (1045), Expect = e-113
Identities = 316/996 (31%), Positives = 496/996 (49%), Gaps = 157/996 (15%)
Query: 55 VLERKIRELNRAFFDNLTEEEEEKVWGEIRSKLAS-SGEVEMLEYIKYGVPI--TVLGRH 111
++E ++ + R + +++ ++V E+R K AS G +LEY+K GV I G
Sbjct: 38 LIESELIDSIRRINQYIEDDDIQQVIQELRGKAASIEGCKSILEYLKNGVYIKSATTGEP 97
Query: 112 DKVILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEV 171
KV ++D+D P++N F + + + I+ D LFINGIP+V IE K + + E
Sbjct: 98 RKVKILDHDTPSHNSFTASRQVVFRRGDQTIRTDIMLFINGIPLVNIELKNP--VGMSET 155
Query: 172 DWRRWSKVHGTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSGDAPASE 231
W+ +A QI+ YE+ L+++VQ GVA D Y P +P + P E
Sbjct: 156 ----WA-------DAYRQIKDYEKTVPELYKYVQMGVAAEDFARYFPIVPW-LDEVPTFE 203
Query: 232 WRYPNEDKP-----------------DIFDLLKPERLLDMLRHYTFFFKKNDGRIKVIAR 274
WR + P DI LL+PER+LD +R+Y + + KVIAR
Sbjct: 204 WRETDGKLPQKSRKQGHEHHTGLPAADILPLLRPERVLDFIRNYIYIRTEFGSTTKVIAR 263
Query: 275 WNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVF 334
QY AA++I++R+ + + E ++ GLIW WQGSGKT M F A+ + NP VF
Sbjct: 264 HMQYHAAERIVERVLRNIRGEDKRNRGLIWHWQGSGKTLTMIFAASKLYRMKELENPTVF 323
Query: 335 FIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYI 394
FIVDR +LE+Q ++E + ER I SI+EL++ I + G+ GL+I
Sbjct: 324 FIVDRRELEEQLYAELAALEIHQPER----IESIAELKRTIAS---DDYRGK---RGLFI 373
Query: 395 TTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALF 454
T IQKF DK D+ + G E + + ++ IDEAHR+QYG LAA M+ +
Sbjct: 374 TLIQKFT-DKLDDITAELREHG-----GETIMDRKNVIVFIDEAHRSQYGLLAAQMKDML 427
Query: 455 PRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEG 514
FFGFTGTPI KR+R+T+ FAYP + +Y + YFI+DSIRDGFT+ I ++
Sbjct: 428 RSAFFFGFTGTPISKRERDTYDRFAYPPEEKY-IHQYFITDSIRDGFTVKITYQ--PRLA 484
Query: 515 VSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEI 574
+ LD L+AFI PE + K + +L + LE+P+ I
Sbjct: 485 GDVHLDRKHLEAFIGVEFEELPESIR----------KDVEESVKRKLDTIKTILENPRRI 534
Query: 575 ERFAEYIAKRIYDDTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKV 634
E AE IAK ++ G FKAMVVA +R ACV +K+ LD +
Sbjct: 535 ELIAEDIAKHFKENIDG-RFKAMVVAPSRRACVLYKRELDRHLPPEY------------- 580
Query: 635 EMAKHFRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEW 694
SE+VMTY + E+I + + L + + +++ I L++E
Sbjct: 581 ----------------SEIVMTYTPRD-EEIIRAYDEELMDK--YHGRNHHEIKNLVLER 621
Query: 695 FQEKDY-PKVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPN-KETGLV 752
F++ D P++LIVTDMLLTGFDAPIL+ MYL KP+ EHRLLQAV R NRPY + KE GL+
Sbjct: 622 FRDPDRNPRILIVTDMLLTGFDAPILQTMYLDKPLKEHRLLQAVARTNRPYRDVKEAGLI 681
Query: 753 VDGVGLLPAVIRVKNIYEMLARQDPK----VLEDFKRNFARSIDEKVEEFENKLQKVKED 808
+D +G++ A +R +E+ ++++ + +E KR + EE + ++ D
Sbjct: 682 IDYIGVMGAELR--RAFELYSKEEYEGAVYDMESMKREY--------EELLRETLRIFSD 731
Query: 809 LSRIGIEVDILKAFKKQGRWKELEAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVIS 868
L G+++++L D V I + L+ K E + E+
Sbjct: 732 LEWDGMDIEVLS---------------DAVELITSDEELEKKFTE--------NYRELRR 768
Query: 869 MYRSLGAHPAKLAYIDDMIVVGAIYSTFIRLIDFSRKKS------KFWDDLLRFVHEHME 922
++ L P + D + IY+ + R++ SRK S +++ L+++H E
Sbjct: 769 LFELLSDQPFIRHGLKDYRWLTVIYTYYQRVV--SRKPSVEAETERYYQKTLKYIHRTTE 826
Query: 923 VGPMREL-IKVKLSEFSGG---------EASFEVVARFYKL-YYTAEDNIHDPFYKAILE 971
RE+ K+ + EF + + Y L Y + +P Y+++ E
Sbjct: 827 ---FREIESKLPVIEFDSDYFENLRKVRDIRDKAALTVYTLNSYVLRNGTRNPIYESVAE 883
Query: 972 RLNRLLEEWINRNIDLKALRKQINILEGQIGEYEKK 1007
++ RLLE+W + +D + L ++ + +I + E++
Sbjct: 884 KVERLLEQWREKTMDYEELYREGAAIIREIWKEERR 919
>gi|11499298 type I restriction-modification enzyme, R subunit [Archaeoglobus
fulgidus] >gi|7484005|pir||C69463 type I
restriction-modification enzyme, R subunit homolog -
Archaeoglobus fulgidus >gi|2648840|gb|AAB89536.1|
(AE000985) type I restriction-modification enzyme, R
subunit [Archaeoglobus fulgidus]
Length = 957
Score = 388 bits (987), Expect = e-106
Identities = 285/930 (30%), Positives = 470/930 (49%), Gaps = 147/930 (15%)
Query: 91 GEVEMLEYIKYGVPITVLGRHDKVI-LIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLF 149
G +++L+ IK GV I K I LIDY +P N F + + +I PD +LF
Sbjct: 67 GSMQILDAIKKGVTIKDSEGILKTIKLIDYANPEANSLVFSRQVSFA----DIIPDITLF 122
Query: 150 INGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKYERYSKPLFRFVQFGVA 209
+NGIP+ IIE K K+ + +E QI++YE+ + LF++VQ G +
Sbjct: 123 VNGIPLAIIECK----------------KMAKSWKEGYAQIKRYEQSAPELFKYVQIGFS 166
Query: 210 YGDKQLYTPTMPRDSGDAPASEWRYPNEDKPDIFDLLKPERLLDMLRHYTFFFKKNDGRI 269
+ D+ +Y P + R P EW KP FD+LKPE LD++R++T + ++ DG I
Sbjct: 167 FADRLVYFPIV-RWEESVPVYEW------KPQ-FDILKPEIFLDLIRYFTIY-REQDGEI 217
Query: 270 -KVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKK 328
KV+ R+ QYRA I++R + E+ GLIW WQG+GKT M F A R
Sbjct: 218 TKVLPRYMQYRAVNSIVERAVGWAKGFEERNKGLIWHWQGTGKTLTMIFSA--LKIRDLI 275
Query: 329 RNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRII 388
NP +FF+VDR++L+ Q S+ E + + ++ I SI L+ E++ + R
Sbjct: 276 GNPSIFFVVDRVELQKQLSD-----ELKNLKISYELIESIDHLK----EVLSHADGKR-- 324
Query: 389 PTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAA 448
G +IT I KF+ ++ + K++ + + + K+ +++ LIDE HRTQYG LAA
Sbjct: 325 --GFFITLIHKFREEE------LAKLREQMEKQHWSIAKRRDVVCLIDEGHRTQYGELAA 376
Query: 449 VMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHE 508
MR++ FF FTGTPI K+ R+T+ F YP E +LD YFI DSI DG+T+ I +
Sbjct: 377 SMRSILKNASFFAFTGTPIAKKGRDTYLAFGYPD--EPYLDRYFILDSIDDGYTVKIAFQ 434
Query: 509 VIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFL 568
+E + LD L+ F+ + PE+ ++K++ ++L L K +V L
Sbjct: 435 SRLDE---VHLDRENLEIFLSSKLEEIPEEY-------REKVE---QDLKRRLNKVKVIL 481
Query: 569 ESPKEIERFAEYIAKRIYDDTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFCSKIEEL 628
E K IER A IA FKAMVVAV+R AC+++K+ALD E
Sbjct: 482 EDKKRIERIARDIASHYIQFVK--PFKAMVVAVSRNACLYYKQALDKFLNE--------- 530
Query: 629 EKDGKVEMAKHFRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSIN 688
+E+VMT+Q N++ E+++ +K R+++ K + I+
Sbjct: 531 --------------------NETEIVMTFQQNDSKELLDYLEK---LRKKYGKSELKEIH 567
Query: 689 RLIVEWFQEKDYPKVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPN-- 746
I+ F++ + PK+LIVTDMLLTGFDAPIL+ +YL KP+ EHRLLQA+ R NRP+
Sbjct: 568 EEIITRFKKYENPKILIVTDMLLTGFDAPILQTLYLDKPLKEHRLLQAIARTNRPFVKDG 627
Query: 747 ---KETGLVVDGVGLLPAVIRVKNIYEMLARQDPK----VLEDFKRNFARSIDEKVEEFE 799
K GLVVD VG+ + K +EM +D + LE+ K + +DE F+
Sbjct: 628 ENLKGAGLVVDYVGVFKFL---KKAFEMYEEEDIRGAAYELEELKEELRKKLDEAFRFFD 684
Query: 800 NKLQKVKEDLSRIGIEVDILKAFKKQGRWKELEAEMDRVRNILAPIALDFKGNEPKAVRL 859
+L ++ + R +L + +++L +E+ + +L ++FK
Sbjct: 685 FELSYDRDTIDRA-----VLVISARADEFRKLYSEIRNLYRLLLEDRIEFKEK------- 732
Query: 860 FNDLHEVISMYRSLGAHPAKLAYIDDMIVVGAIYSTFIRLIDFSRKKSKFWDDLLRFVHE 919
F+ L EV +Y ++ + + +K+ +F+ + L+F+HE
Sbjct: 733 FDLLSEVYHVYLQR----------ENQLEA-----------EIEQKRDQFYREALKFIHE 771
Query: 920 HMEVGPMRELIKV-KLSEFSGGEASFEVVARFYKLYYTAEDNIHDPFYKAILERLNRLLE 978
++V +++ + ++++ + R Y + + + + ++ R+ R+++
Sbjct: 772 TIDVQRIKKDYPIIEINDEFLERVKKKEKRRIYDILFPVRNYARKVGDEDLIARVERIVK 831
Query: 979 EWINRNIDLKALRKQINILEGQIGEYEKKR 1008
+W R D + +++ L ++ E K+R
Sbjct: 832 DWNERRRDADEVYREVLSLAEKVNEERKER 861
>gi|10954527 type I restriction enzyme [Methanococcus jannaschii]
>gi|2129337|pir||G64514 type I restriction enzyme homolog
- Methanococcus jannaschii plasmid pURB800
>gi|1522673|gb|AAC37109.1| (L77118) type I restriction
enzyme [Methanococcus jannaschii]
Length = 1042
Score = 208 bits (523), Expect = 4e-52
Identities = 275/1128 (24%), Positives = 467/1128 (41%), Gaps = 219/1128 (19%)
Query: 35 EMVSKYSGLEDSLGDFVLWNVLERKIRELNRAFFDNLTEEEEEKVWGEIRSKLASSGEVE 94
E+ +Y+ E S D +L N + I+ +N + L + + V G++
Sbjct: 53 ELTPEYNERE-SYRDAILKNRFIKAIKNINPWLTEELALKVYKTVTNIDNPDFNMRGKI- 110
Query: 95 MLEYIKYGVPITVLGRHDK----VILIDYDDPTNNIFFFLHEAKYPGFPEN---IKPDFS 147
E + GV + +K V LID+++ N F ++ + + EN +PD
Sbjct: 111 FYEMLINGVKLEFKENGEKKTRFVKLIDFENINKNEFLVANQFEVEYYYENGRFRRPDLV 170
Query: 148 LFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKYE-----------RY 196
+FINGIPI I E K+ + + + H T+ + + Q+ +Y +Y
Sbjct: 171 VFINGIPIAIFEFKSPKSNQTAKDAFND----HKTKMKDIPQLYQYAQILVVSDGLETKY 226
Query: 197 SKPLFRFVQFGVAYG----------DKQLYTPTMPRDSGDAPASEWRYPNEDKPDIFDLL 246
P + +F V G + Y TM + G+ Y + D + L
Sbjct: 227 GSPTSDWDRFFVWEGVESDDDVEVIEVDNYGNTMYKYKGNP------YTSLDIL-LMGLF 279
Query: 247 KPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEK---YLSRESEKKNGLI 303
K E L++ L + KK K+IA + Q+ KK + R K Y +++ G++
Sbjct: 280 KKEHLIEFLEDFIIHDKK-----KIIATYYQFYTVKKAVDRTIKSVLYGETPEDRRIGIV 334
Query: 304 WQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFD 363
W QG+GK+ M F A L + + P++ F+ DR++L++Q N+F SV +
Sbjct: 335 WHAQGTGKSITMLFYAKKALKQKELNYPLLVFLTDRLELDEQLYNVFSSVFSEA-----E 389
Query: 364 RIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAE 423
R SI+EL++ I++ P G+ TIQKF RK K E
Sbjct: 390 RAESIAELQELIKKT----------PGGIIFATIQKFG----------RKSKDEHY---P 426
Query: 424 KAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKD 483
+ I+ + DEAHR+ YG LA +R P F FT TPI +DR+TF F
Sbjct: 427 FLTDRNNIIIIADEAHRSHYGTLAQNLRKAIPNASFLAFTATPIDYKDRSTFLVF----- 481
Query: 484 GEYFLDVYFISDSIRDGFTLDIVHEV------IEEEGVSIALDESKLKAFIDAYQLNDPE 537
G+Y + Y I + R G + I +E + E + + DE I NDPE
Sbjct: 482 GDY-ISAYPIDKAKRHGVVVPIYYEARLVELHLTNEFIDLEFDE------ISERVANDPE 534
Query: 538 DVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIER-FAEYIAKRIYDDTMGFSFKA 596
E S +E+ +L K + + ++ + E+ KR+ D F KA
Sbjct: 535 TKE------------SIKEVFAKLEKIMLTEDYLSKVSKDIIEHFNKRLQD----FDGKA 578
Query: 597 MVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMT 656
MVV ++R+ V K + NA +++ VVM+
Sbjct: 579 MVVTISRKVAVELYKWITKQ----------------------------PNAPKIA-VVMS 609
Query: 657 YQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDA 716
S+ E+F ++T++E + L E+ + K++IV DM LTGFD
Sbjct: 610 ---GNKSKDPEDFHPHIRTKKELEN--------LAKEFKDPESDLKMVIVVDMWLTGFDV 658
Query: 717 PILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIYEMLARQD 776
P L MY KP+ H L QA+ RVNR + +K GL+VD +G+ + + + Y AR+D
Sbjct: 659 PCLHTMYFLKPMKNHSLAQAIARVNRVFKDKPGGLIVDYIGIADDLSKSLSKYSSEARKD 718
Query: 777 -----PKVLEDFKRNFARSIDEKVEE-FENKLQKVKEDLSRIGIEVDILKAFKKQGRWKE 830
V+E+ KR + EKV F+N K + LS + + +KA+++ K+
Sbjct: 719 LMTDIKVVIEEMKRRY-----EKVTSYFKNINYKDWKKLSSEDLSLLTVKAYQRVA--KD 771
Query: 831 LEAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVISMYRSLGAHPAKLAYIDDMIVVG 890
+ + VRN++A + +Y HP + DD+
Sbjct: 772 DNTKKEFVRNVIA----------------------LKKLYLLARPHPETIGIKDDLEFFE 809
Query: 891 AIYSTFIRLIDFSRKKSK-----FWDDLLRFVHEHM---EVGPMRELIKVKLSEFS--GG 940
I ++ +S KK + +D+ + + + E+ + E++K + E S
Sbjct: 810 MIKKMIVK---YSTKKIREISQDLENDIQSLISKSISAKELVDVFEMLKKEKPELSVLSD 866
Query: 941 EASFEVVARFYKLYY------TAEDNIH-----DPF-YKAILERLNRLLEEWINRNIDLK 988
E E+ YK Y D+I +P +K ERLN ++E++ + I
Sbjct: 867 EFLSEIAKIEYKDYVRDVLIKILNDDIRVRMAKNPIRFKKFSERLNEVIEKYRIKVITTA 926
Query: 989 ALRKQINILEGQI--GEYEKKRAGKTWQESLLESVKFYVKNYLGLEGVEFKKFQRELKR- 1045
+ +++ L +I E K G T +E + N + +K +E+ R
Sbjct: 927 EMIEELVNLAKEIRKAAEEGKELGLTEEELAFYDLLLSYPNIPLTDKKRVEKIAKEIARM 986
Query: 1046 ----LRRLNPRTVKRLSSSLLDDIMEAIKDDNLNKYRELSKEIDRLVE 1089
++ + + K L S + + + + + Y ++K D L E
Sbjct: 987 MSGYIKARDWKKKKNLQSKIRAKLKIILMKEGIKDYSLINKISDDLFE 1034
>gb|AAG18735.1| (AE004978) type I restriction modification enzyme, R subunit; RmeR
[Halobacterium sp. NRC-1]
Length = 1000
Score = 207 bits (522), Expect = 5e-52
Identities = 279/1125 (24%), Positives = 462/1125 (40%), Gaps = 221/1125 (19%)
Query: 2 ALIPESAVHREIKENLLRIGWE----DGNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLE 57
+L E V + L +GWE DG++ + + +YS S D + W++L
Sbjct: 12 SLPSEQGVETSLLSWLDGLGWETHGLDGSQGASVLDE----RYSR---STADVIYWDLLA 64
Query: 58 RKIRELNRAFFDNLTEEEEEKVWGEIRSKLAS----SGEVEMLEYIKYGVPITVLGRHDK 113
+ LN D +TE+ +++ ++ L + +G E + G + G
Sbjct: 65 EQAIALN----DAVTEDNVDRLVSSLKLDLDTDDLLAGNREFYAILTKGKQFQIDGEDGT 120
Query: 114 ----VILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELE 169
V LID+ D N F +++ I+PD +LF+NGIP+V +E K+ +
Sbjct: 121 EYVYVDLIDFADIERNRFHAVNQFSVSR-GTTIRPDVNLFVNGIPLVTMELKSLA----Q 175
Query: 170 EVDWRRWSKVHGTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDS----- 224
+ D+ +A++ + YE LF F VA L + +
Sbjct: 176 DNDYY----------DAISDLHNYEETVPRLFVPGLFNVAADTTALRYGAVGAPTQFYMK 225
Query: 225 -GDAPASEWRYPNEDKPDIFDLLKPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKK 283
DAP ++ NE + + L P LLD+ + + F+ ++ G K++ R+ QY A +
Sbjct: 226 WADAP-EQYESDNEMRQAVQALCNPATLLDICKRFVFYDQRAGGDAKIVPRYMQYYAVTR 284
Query: 284 IIKRIEKYLSRESEKKNG-----LIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVD 338
++ R+ + + G L+W QGSGK+F M + A L++ P VF IVD
Sbjct: 285 LLDRVREGEPHPDPDERGHLDRGLVWHTQGSGKSFTMLYAAENLLSQDILDTPQVFLIVD 344
Query: 339 RIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQ 398
L Q + ++ FE+ S + + I+ + E E GR + + +TTIQ
Sbjct: 345 TDKLASQMRDTLSNI---GFEQ--------SVVAESIDHLQELIEQGR---SEVVLTTIQ 390
Query: 399 KFQYDKFKDMVRVRKVKGEEKFEAEKAVK-KPEILFLIDEAHRTQYGRLAAVMRALFPRG 457
KFQ + E + E++ + DEAHR L + + A P
Sbjct: 391 KFQ-------------------DVEPNTQGNDEVVVMSDEAHRFMEKDLGSRLDAALPGC 431
Query: 458 MFFGFTGTPI----FKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEE 513
FGFTGTP+ K DRNTF EF+ +GE +L Y + + I DG L + + +
Sbjct: 432 FHFGFTGTPVREGDEKSDRNTFDEFS--PEGEEYLHRYSVKEGIEDGLILPVYFRLRHQ- 488
Query: 514 GVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKE 573
+ +DE+ L E+ E G + K RE E SR E
Sbjct: 489 -MEWNVDEAGL-----------DEEFEQQFAGLTTEEK---REFIRESVTSRELAELEPR 533
Query: 574 IERFAEYIAKRIYDDTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGK 633
+E + I +D +K MVV +R++ + + L
Sbjct: 534 VETVVDEIDTH-FDGVDKNGWKGMVVTPSRKSAAMYGERL-------------------- 572
Query: 634 VEMAKHFRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVE 693
+ R +E EV+ T ++ S++I++F E +++D IV+
Sbjct: 573 ---------MERRSEDEIEVLYT-ATSDDSDLIQQF------HTENEERDQ------IVK 610
Query: 694 WFQEKDYPKVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVV 753
F ++D PK+L+V +MLLTGFDAP L+ MYL + + H L+QA+ R NR KE G +V
Sbjct: 611 QFNDEDEPKLLVVHNMLLTGFDAPNLKTMYLDRNLKNHNLMQAIARTNRVAEGKENGEIV 670
Query: 754 DGVGLLPAVIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSRIG 813
D G+ +NI + L DP+ E AR +E E E +L V
Sbjct: 671 DFQGVF------ENIDDAL-DYDPETQE----YAARDREELFAELETQLDFV-------- 711
Query: 814 IEVDILKAFKKQGRWKELEAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVISMYRSL 873
+DI + + ++ + RV P FK + R +L+E +S L
Sbjct: 712 --LDIFEDIPMDDSQEAIDQCLARVST--HPEKRKFK----QGFRRLQNLYESVSPDGRL 763
Query: 874 GAHPAKLAYIDDMIVVGAIYSTFIRLIDFSRKKSKFWDDLLR-----FVHEHMEVGPMRE 928
A+ DD + +Y+ F R +RK +D +R + EH++VG
Sbjct: 764 ----AQAGIQDDYKWLARVYTAFQR--HHNRKDRP--EDAMREKTRDIIEEHVDVGE--- 812
Query: 929 LIKVKLSEFSGGEASFEVVARFYKLYYTAEDNI-------------HDPFYKAILERLNR 975
IK + G+ E + TA N+ +P YK + ER+N
Sbjct: 813 -IKRDFPVYELGQGHLEAIEDMDPA--TAATNVAHATREHLQPKTGQNPKYKRLSERVND 869
Query: 976 LLEEWINRNID-------LKALRKQINILEGQIGEYEKKRAGKTWQESLLESVKFYVKNY 1028
++EEW + L + +++ +E Q G+ K +A L E V +
Sbjct: 870 IVEEWEQGDRSDPEAVEALTEVEEEVLTVEAQAGDQAKAQAEFAIYTHLTEETPAAVDSE 929
Query: 1029 LGLEGVEFKKFQRELKRLRR------LNPRTVKRLSSSLLDDIME 1067
+ + +R+ R N TV+ L LLD +++
Sbjct: 930 DEAQAIAADIVDEFEERIDRGYPGWEANETTVQTLEVVLLDALLK 974
>pir||A82522 type I restriction-modification system endonuclease XF2739
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9107977|gb|AAF85524.1|AE004080_6 (AE004080) type I
restriction-modification system endonuclease [Xylella
fastidiosa]
Length = 1058
Score = 206 bits (519), Expect = 1e-51
Identities = 217/797 (27%), Positives = 334/797 (41%), Gaps = 152/797 (19%)
Query: 1 MALIPESAVHREIKENLLRIGWEDGNEKFGIEEHEMVSK--YSGLEDSLGDFVLWNVLER 58
MA + E+ + + + E L +G + IE E + Y S + VL
Sbjct: 15 MAFLSEATLEQALLEQLRALG-------YSIEREENIGPDGYRPERASHDEVVLKQRFVD 67
Query: 59 KIRELNRAFFDNLTEEEEEKVW-GEIRSKLASSGEVEMLEYIKYGVPITVLGRHD----- 112
+ LN ++ KV E+ S L + + L I GV + +
Sbjct: 68 AVARLNPGLPPEARQDAIRKVTQSELPSLLEENRRIHRL--ITEGVDVEYYAQDGTLTAG 125
Query: 113 KVILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVD 172
V LID+D P N + +++ N +PD LF+NG+P+ +IE KA G
Sbjct: 126 NVALIDFDHPQQNDWLAVNQFVVIADHYNRRPDVVLFVNGLPLAVIELKAPG-------- 177
Query: 173 WRRWSKVHGTEEEALTQIRKYERYSKPLFRF-----------VQFGVAYGDKQLYTPTMP 221
++ T A Q++ Y+ LF +FG D + + P
Sbjct: 178 -----SINATLIAAFNQLQTYKEQIPALFNTNALLVTSDGMTARFGALSADLERFMPWRT 232
Query: 222 RDSGD-APASEWRYPNEDKPDIFDLLK----PERLLDMLRHYTFFFKKNDGRIKVIARWN 276
D D AP + P++ L++ P RLLD+LRH+T F K + G K+IA ++
Sbjct: 233 TDGTDIAP--------KGVPELATLIEGICEPHRLLDLLRHFTVFRKTDAGLAKIIAGYH 284
Query: 277 QYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFI 336
Q+ A ++ I S + ++ G+IW QGSGK+ +M F A + NP + +
Sbjct: 285 QFHAVRQAINSTVAASSPQGNQRIGVIWHTQGSGKSLLMAFYAGQLVKHPAMANPTLVVL 344
Query: 337 VDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITT 396
DR DL+DQ F D + + +S ++RK + G+ TT
Sbjct: 345 TDRNDLDDQLFTTFSQCSDL-IRQTPVQAQSRDQVRKLLNR----------ASGGVIFTT 393
Query: 397 IQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAV------- 449
+QKF G+ E + ++ + DEAHR+QYG A V
Sbjct: 394 LQKF---------------GD---ITEPLTTRRNVVVIADEAHRSQYGFKAKVDTKTGKI 435
Query: 450 -------MRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFT 502
MR P GFTGTPI D NT F G Y +D+Y IS ++ DG T
Sbjct: 436 SYGFAKYMRDALPNASCIGFTGTPIEADDVNTPAVF-----GNY-IDIYDISRAVEDGAT 489
Query: 503 LDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELR 562
+ I + E IALDE++ K IDA ++N + ++ + K K ++ E
Sbjct: 490 VPIYY---ESRLARIALDEAE-KPQIDA-EVNALTEADSEAEQERFKKKWATVE------ 538
Query: 563 KSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFC 622
+ S K + A+ I D KAMVV ++R CV
Sbjct: 539 ---TLVGSDKRLALIAKDIITHCEDRLAALDGKAMVVCMSRRICVAL------------- 582
Query: 623 SKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKK 682
D V + + A L ++VMT ++ + + K RR+
Sbjct: 583 -------YDHIVALRPDWHSTDHKAGSL-KIVMTGTASDPPQWRQHIGN--KARRD---- 628
Query: 683 DYDSINRLIVEWFQE-KDYPKVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVN 741
L+ E ++ KD K++IV DM LTGFDAP + MYL KP+ H L+QA+ RVN
Sbjct: 629 -------LLAERARDPKDPLKLVIVRDMWLTGFDAPCMHTMYLDKPMQGHGLMQAIARVN 681
Query: 742 RPYPNKETGLVVDGVGL 758
R + +K GL+VD +G+
Sbjct: 682 RVFRDKPAGLIVDYIGI 698
>pir||F64114 type I site-specific deoxyribonuclease (EC 3.1.21.3) chain hsdR -
Haemophilus influenzae (strain Rd KW20)
>gi|1574743|gb|AAC22934.1| (U32808) type I restriction
enzyme (hsdR) [Haemophilus influenzae Rd]
Length = 1055
Score = 187 bits (471), Expect = 4e-46
Identities = 185/670 (27%), Positives = 300/670 (44%), Gaps = 116/670 (17%)
Query: 112 DKVILIDYDDPTNNIFFFLHEAKYPGFPENIK-PDFSLFINGIPIVIIEAKAKGIIELEE 170
+ V L+D++ NN F +++ + + PD F+NG+P+V+ E K E
Sbjct: 108 EMVRLVDFEHWGNNRFVAVNQLEIRSRKGGKRIPDIIGFVNGLPLVVFELKNP---LRES 164
Query: 171 VDWRRWSKVHGTEEEALTQIRKYERYSKPLFRFV-QFGVAYGDKQLYTPTMPRDSGDAPA 229
D + T ++ + ++ Y + V + G D Q +TP D + A
Sbjct: 165 ADLLQAFNQFETYKDEIAELFVYNQALIISDGIVARLGSLSADFQRFTPWKVVDEKNKSA 224
Query: 230 SEWRYPNEDKPDIFDLLKPERLLDMLRHYTFFFKKNDGR-IKVIARWNQYRAAKKIIKRI 288
+ + +E + + L++PE LLD +R++ F + + G+ IK IA ++QY + +
Sbjct: 225 RLY-FDDELQSLLNGLMQPEDLLDYIRYFVLFERDSVGKTIKKIAAYHQYYGVNEAVDST 283
Query: 289 EKYLSRESEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSN 348
S + +++ G++W QGSGK+ M F A L + + +NP + + DR DL+ Q
Sbjct: 284 IWATSEKGDRRIGVMWHTQGSGKSISMLFYAGKLLAQPELKNPTIVVVTDRNDLDGQLFQ 343
Query: 349 IFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDM 408
F S +D + E R ++ +++ E G G++ TTIQKF +
Sbjct: 344 TFSSGKDL-----IKQTPQQVEDRDQLRQLLAQNEVG-----GVFFTTIQKFALN----- 388
Query: 409 VRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYG------------RLAAVMRALFPR 456
EE+ ++ I+ + DEAHR+QYG A +R P
Sbjct: 389 --------EEESRFPILNERNNIIVISDEAHRSQYGFTQKLHNGKFQTGYARHLRDALPN 440
Query: 457 GMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVS 516
F GFTGTPI D++T F G Y + +Y + D++ DG T+ IV++ + ++
Sbjct: 441 ASFIGFTGTPISLEDKDTQDVF-----GRY-VSIYDLQDAVEDGATVPIVYDDARQIRLN 494
Query: 517 IALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSR--ELAEELRKSRVFLESPKEI 574
D L A IDA +P L R+K L R ELA +
Sbjct: 495 -KKDHDALFAEIDALLEEEP---STSLRLREKLLGSQERLIELAAD-------------- 536
Query: 575 ERFAEYIAKR--IYDDTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDG 632
F ++ AKR + D KAM+V +R+ CV + E+ I E G
Sbjct: 537 --FVQHFAKRNEVVDS------KAMMVVSSRQICVDLYNQIIALHPEWHSDNINE----G 584
Query: 633 KVEMAKHFRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIV 692
+ ++VMT ++T E+ + + K++ ++ R
Sbjct: 585 AI-----------------KIVMTGSASDTPEM---------QKHIYSKQEKQTLERR-- 616
Query: 693 EWFQEKDYP-KVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKET-- 749
F++ + P KV+IV DM LTGFDAP MYL KP+ H L+QA+ RVNR + NK
Sbjct: 617 --FKDPNDPLKVVIVRDMWLTGFDAPCCNTMYLDKPMKGHNLMQAIARVNRVFANKSREN 674
Query: 750 -GLVVDGVGL 758
GL+VD VGL
Sbjct: 675 GGLIVDYVGL 684
>pir||C81302 probable type I site-specific deoxyribonuclease (EC 3.1.21.3) chain
R Cj1549c [imported] - Campylobacter jejuni (strain
NCTC 11168) >gi|6968968|emb|CAB73965.1| (AL139078)
putative type I restriction enzyme R protein
[Campylobacter jejuni]
Length = 1031
Score = 184 bits (462), Expect = 5e-45
Identities = 189/701 (26%), Positives = 298/701 (41%), Gaps = 142/701 (20%)
Query: 110 RHDKVILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELE 169
R D + LID+++ +NN F ++ EN PD L+INGIP+V++E K+
Sbjct: 99 RADIINLIDFNNASNNEFIATNQLSITEAKENKIPDVVLYINGIPLVLMELKSP------ 152
Query: 170 EVDWRRWSKVHGTEEEALTQIRKYERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSGDAPA 229
S + T A QI Y++ +F + F V ++ D A
Sbjct: 153 -------SDENATINSAYNQINTYKQTIPSIFTYNAFCVISDGYFARAGSISADFSRFMA 205
Query: 230 SEWRY-------PN---EDKPDIFDLLKPERLLDMLRHYTFFFKKNDGRI---------K 270
W+ PN E K I +L P+ LLD++ ++ F K+ + K
Sbjct: 206 --WKSSDGINYAPNKSLEIKTLIDGMLNPKTLLDIICNFIVFEKEQIRDLNGILSIKTTK 263
Query: 271 VIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRN 330
IA ++QY A K I R S++ +KK G++W QGSGK+ M F + + N
Sbjct: 264 KIACYHQYYAVNKAISRTITASSKDGDKKGGVVWHTQGSGKSLSMVFYSAKAIKALN--N 321
Query: 331 PIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPT 390
P + I DR DL+DQ F S + + + K+ + +E R+
Sbjct: 322 PTILLITDRNDLDDQLFGTFASCANL-----------LRQEPKQANDKEHLKELLRVASG 370
Query: 391 GLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAV- 449
G+ TTIQKF + + FE + I+ + DEAHRTQYG A V
Sbjct: 371 GVVFTTIQKFSPEN------------DNVFECLSL--RDNIIVIADEAHRTQYGFDAKVV 416
Query: 450 ---------------------MRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFL 488
+R P + GFTGTPI D NT F G Y +
Sbjct: 417 EEKSKSGDVLGQKIVYGFAKYLRDALPNATYIGFTGTPIESHDINTPAVF-----GNY-I 470
Query: 489 DVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKK 548
D+Y IS ++ DG T+ I +E S+L ++ E+ + + +
Sbjct: 471 DIYDISRAVEDGATVSIYYE-------------SRLA------KIELSEEGKRLVNELDE 511
Query: 549 KLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVAVNREACVH 608
KL+ + A+ K + S +++ A+ I K + K M+V+++R
Sbjct: 512 KLENQDSQKAKAT-KLEALVGSTSRLKQIAKDIVKHFETRSSKLGGKGMIVSISRS---- 566
Query: 609 FKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHNETSEVIEE 668
+A K Y ++ K+ + H EL A + VVMT ++ E +
Sbjct: 567 ------VAIKLY--------DEIIKIRPSWHSDELSSGAIK---VVMTSSSSDGVEFSKH 609
Query: 669 FKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILRVMYLYKPI 728
K +++F +I+ D K++IV DM LTGFD P L +Y+ KP+
Sbjct: 610 HTS--KIQKQFLANRMRNID----------DELKLVIVVDMWLTGFDVPSLHTLYIDKPM 657
Query: 729 FEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIY 769
H L+QA+ RVNR Y +K +GLVVD +G+ + + + Y
Sbjct: 658 KGHNLMQAIARVNRVYKDKPSGLVVDYLGIASDLKKALSFY 698
>pir||JC5216 type I site-specific deoxyribonuclease (EC 3.1.21.3) Hsd chain R
[validated] - Pasteurella haemolytica
>gi|1685100|gb|AAC44668.1| (U46781) HSDR [Pasteurella
haemolytica]
Length = 1055
Score = 180 bits (452), Expect = 8e-44
Identities = 201/796 (25%), Positives = 332/796 (41%), Gaps = 152/796 (19%)
Query: 1 MALIPESAVHREIKENLLRIGWED--GNEKFGIEEHEMVSKYSGLEDSLGDFVLWNVLER 58
M I E+ + + L +GW+ G + EHE D + +L +L +
Sbjct: 1 MITINENTIEQSAIATLQSLGWDYTYGKKILAGLEHEW-------RDGTAEVILKPLLAQ 53
Query: 59 KIRELNRAFFDNLTEEEEEKVWGEI---RSKLASSGEVEMLEYIKYGVPIT--VLGRH-- 111
I + N NL E E V ++ S + G + ++++ GV IT + G
Sbjct: 54 AIAKFN----PNLPACEVENVVAQVCRADSGDLADGNRQAYDWLRNGVKITYQLYGEQVS 109
Query: 112 DKVILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEV 171
D V LID+ P NN F +++ G PD F+NG+P+V+ E K
Sbjct: 110 DVVQLIDFQRPENNDFRIVNQLDISGKKGKRIPDLIGFVNGLPLVVFELKNP-------- 161
Query: 172 DWRRWSKVHGTEEEALTQIRKYERYSKPLFRFVQ-----------FGVAYGDKQLYTPTM 220
K + +A Q++ Y+ LF F Q G D +TP
Sbjct: 162 -----LKENADIGKAFAQLQTYKDEISDLFVFNQALVISDGIVARIGSLTADFDRFTPWR 216
Query: 221 PRDSGDAPASEWRYPNEDKPDIFDLLKPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRA 280
D + + + +E + ++ P+ LLD ++++ F + DG+ ++I + Y
Sbjct: 217 VVDEKNQ-SKRIVFEDELTALLQGVMTPKNLLDYVQNFVVF--ERDGKNRLIKKIGAYHQ 273
Query: 281 AKKIIKRIE-KYLSRESEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDR 339
+ + ++ L+ +K G+ W QGSGK+ M F A L++ +NP + + DR
Sbjct: 274 FYGVNEAVDCTLLAATGNRKIGVFWHTQGSGKSLSMLFYAGKVLSQSSLKNPTLVLVTDR 333
Query: 340 IDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQK 399
DL+ Q F E + ++ R + + S G G+ TTIQK
Sbjct: 334 NDLDGQLYATFCGGEALLKQTPIQ-----ADGRDELRSALASRSAG-----GVIFTTIQK 383
Query: 400 FQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYG-------------RL 446
F ++GE ++ I+ + DEAHR+QYG
Sbjct: 384 FGL-----------MEGELAHPVLN--ERENIIVITDEAHRSQYGFSQKINHKGEYREGY 430
Query: 447 AAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIV 506
A +R+ P F GFTGTPI D++T + F G+Y + +Y D++ DG T+ I+
Sbjct: 431 AKHLRSALPNASFIGFTGTPIELDDKDTQEVF-----GKY-VSIYDFEDAVEDGATVPII 484
Query: 507 HEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRV 566
+ E +S+ K +A QL D ++ R+K + SR
Sbjct: 485 Y---EPRQISLGESGEFSKVMEEAQQLIDDDENSYNFRLREKLHSVDSR----------- 530
Query: 567 FLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFCSKIE 626
+++ AE I + T KAMVV ++R CV + + E+ + +
Sbjct: 531 -------LQKMAEDIIAHYDERTKQQDGKAMVVVMSRAICVKLYEKITALRPEWHSNDVL 583
Query: 627 ELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDS 686
+ G + ++VMT ++ + E+QK + D
Sbjct: 584 Q----GSI-----------------KIVMTSNASDPA--------------EWQKHNQD- 607
Query: 687 INRLIVEWFQEKDYP-KVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYP 745
+ + + F++ D P ++IV DM LTGFDAP MY+ KP+ H L+QA+ RVNR +
Sbjct: 608 -KKTLEKRFKDPDDPLNIVIVRDMWLTGFDAPCCNTMYIDKPMSGHNLMQAIARVNRVFR 666
Query: 746 NKET---GLVVDGVGL 758
NK GL+VD VGL
Sbjct: 667 NKSRENGGLIVDYVGL 682
>pir||B64695 type I restriction enzyme R protein - Helicobacter pylori (strain
26695) >gi|2314575|gb|AAD08445.1| (AE000640) type I
restriction enzyme R protein (hsdR) [Helicobacter pylori
26695]
Length = 993
Score = 165 bits (414), Expect = 2e-39
Identities = 184/765 (24%), Positives = 336/765 (43%), Gaps = 135/765 (17%)
Query: 76 EEKVWGEIRSKLASSGEVEMLEYIKYGVPITVLGRHDKVI---LIDYDDPTNNIFFFLHE 132
E K+ +++ L + + E + YGV + +++ LID+ D + N F E
Sbjct: 59 EHKIHNALKNDLYEANQT-FYELLIYGVKTKISQKNENTQTTWLIDWKDISENEFSVAEE 117
Query: 133 AKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRK 192
G P +PD L++NGI + ++E K + V + L +K
Sbjct: 118 VSVKG-PNAKRPDVVLYVNGIALGVLELKKSSV------------SVESAIRQNLDNQKK 164
Query: 193 YERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSGDAPASEWRYPNEDKPDIFD----LLKP 248
+ + F+ +Q +A + Q + ++ + W+ K ++F+ LK
Sbjct: 165 --EFIRDFFKTIQLVMAGNESQGLRYGVI-ETEEKYYLSWKEEGVLK-NLFETIECFLKK 220
Query: 249 ERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQG 308
ER L+ + + F K K AR++QY A IK+ ++++ R K+ G+IW QG
Sbjct: 221 ERFLEFIHDFLIFDKGK----KKCARFHQYFA----IKKTQEFIQR---KEGGIIWHTQG 269
Query: 309 SGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSI 368
SGK+ M ++ W K+ V ++DR +L+ Q +F+ + + D R+
Sbjct: 270 SGKSLTMVWLTRWLRRNIKQAR--VLIVIDRRELDAQIKGVFQGIGE-------DLYRAD 320
Query: 369 SELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKK 428
S+ + + + E++E L + + KF + +D+ + +K
Sbjct: 321 SK-KDLLSALFENKEF-------LVGSLVHKFDDNDLEDLKKQPVLK------------- 359
Query: 429 PEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFL 488
E + L+DE HRTQ +L M++L P +F F+GTP+ K+D+ T QE G Y +
Sbjct: 360 -EWVVLVDECHRTQSAKLHKAMKSLLPNAIFIAFSGTPLLKQDKKTSQEVF----GNY-I 413
Query: 489 DVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKK 548
Y ++++ D LD+ +E +D Y ++ PE ++ + +
Sbjct: 414 HCYKFNEAVSDRVVLDLNYEA----------------RSVDQY-VSSPEKLDEYF---EL 453
Query: 549 KLKMSSRELAEELRKSRVFLESP-KEIERFAEYIAKRIYD-----DTMGFSFKAMVVAVN 602
K + + EL+K V L+ +R A + + D AM+VA +
Sbjct: 454 KTQCLNDIAKTELKKKWVNLQKVFSTKDRLARIVQDIVLDMAKLPRLRSEKGNAMLVAES 513
Query: 603 -REACVHFKKALDMAFKE------YFCSKIEELEKDG--KVEMAKHFRELCRNAERLSEV 653
AC +F+ L+ K+ + I +L+ G + E + +R C+ + +
Sbjct: 514 VYNACQYFELFLETELKDKVAVITSYEPNIADLKDCGSDESEESYKYRAYCKMLQNFFDE 573
Query: 654 VMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTG 713
++ KK L +EF++K D + E + K+LIV D LLTG
Sbjct: 574 -------------KDEKKALNKIKEFEEKVKD-------RFINEPNRMKLLIVVDKLLTG 613
Query: 714 FDAPILRVMYLYKPIFEHRLLQAVTRVNR-PYPNKETGLVVDGVGLLPAVIRVKNIYEML 772
FDAP L +Y+ K + +H L QAV RVNR +K+ G ++D L ++ V + Y
Sbjct: 614 FDAPSLTYLYIDKKMQDHGLFQAVCRVNRLDGEDKDFGCIIDYSDLFDSLQEVHSDY--- 670
Query: 773 ARQDPKVLEDFKRNFARS-IDEKVEEFENKLQKVKEDLSRIGIEV 816
K E+++R + I +K ++ + KL++ ++ L +G V
Sbjct: 671 ---TNKAFENYEREDIQGLISDKAQKIKKKLEEARDQLRSLGESV 712
>pir||C71808 type I restriction enzyme (restriction chain) - Helicobacter pylori
(strain J99) >gi|4156050|gb|AAD07007.1| (AE001565) TYPE
I RESTRICTION ENZYME (RESTRICTION SUBUNIT) [Helicobacter
pylori J99]
Length = 991
Score = 157 bits (394), Expect = 5e-37
Identities = 184/774 (23%), Positives = 334/774 (42%), Gaps = 135/774 (17%)
Query: 76 EEKVWGEIRSKLASSGEVEMLEYIKYGVPITVLGRHDKVI--LIDYDDPTNNIFFFLHEA 133
E+++ +++ L + + + E + YGV + + LID+ D + N F E
Sbjct: 58 EQEIHTALKNDLYEANQ-KFYELLIYGVKTKISLNENTQTHWLIDWKDVSKNEFSVAEEV 116
Query: 134 KYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKY 193
G P +PD L++NGI + ++E K + S G + Q +++
Sbjct: 117 SAKG-PNMKRPDIVLYVNGIALGVLELKKSSV-----------SVESGIRQNLDNQKKEF 164
Query: 194 ERYSKPLFRFVQFGVAYGDKQLYTPTMPRDSGDAPASEWRYPNEDKPDIFD----LLKPE 249
R F+ +Q +A + Q + ++ + W+ K ++F+ L +
Sbjct: 165 IR---DFFKTIQLVMAGNESQGLKYGVI-ETEEKYYLSWKEEGVQK-NLFETIECFLDKK 219
Query: 250 RLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGS 309
R L+ + + F K K AR++QY A IK+ ++++ R K+ G+IW QGS
Sbjct: 220 RFLEFIHDFLIFDKGQ----KKCARFHQYFA----IKKTQEFIQR---KEGGIIWHTQGS 268
Query: 310 GKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSIS 369
GK+ M ++ W K+ V + DR +L+ Q +F+ + ++ + +
Sbjct: 269 GKSLTMVWLTRWIRRNIKQAR--VLIVTDRRELDAQIQGVFQGIGEKIYR---------A 317
Query: 370 ELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKP 429
+ +K + ++ F+ KF V K + + +K
Sbjct: 318 DSKKDLLSVL--------------------FENKKFLVGSLVHKFDDNDLEDLKKQPVLK 357
Query: 430 EILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLD 489
E + L+DE HRTQ G+L M++L P +F F+GTP+ K+D+ T QE G+Y +
Sbjct: 358 EWIVLVDECHRTQSGKLHKAMKSLLPNAIFIAFSGTPLLKQDKKTSQEVF----GDY-IH 412
Query: 490 VYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKK 549
Y ++++ D LD+ +E E ++ PE ++ + + +
Sbjct: 413 CYKFNEAVSDKVVLDLNYEARSVE-----------------QYVSSPEKLDEYFELKTQN 455
Query: 550 LKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGF------SFKAMVVAVN- 602
L +++ EL+K V L+ + E+I + I D AM+VA +
Sbjct: 456 LNEAAK---TELKKKWVNLQKVFSTKDRLEHIVQDIVLDMAKLPRLSNGKGNAMLVAESV 512
Query: 603 REACVHFKKALDMAFKE------YFCSKIEELEKDG--KVEMAKHFRELCRNAERLSEVV 654
AC +F+ L+ K+ + I +L+ G + E + +R C+ +
Sbjct: 513 YNACRYFELFLETELKDKVAVITSYEPNIADLKDCGSNESEESYKYRAYCKMLQNF---- 568
Query: 655 MTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGF 714
NE E KK L +EF+++ + + E K+LIV D LLTGF
Sbjct: 569 ----FNEKDE-----KKALNKIKEFEEE-------VKKRFINEPARMKLLIVVDKLLTGF 612
Query: 715 DAPILRVMYLYKPIFEHRLLQAVTRVNR-PYPNKETGLVVDGVGLLPAVIRVKNIY---- 769
DAP L +Y+ K + +H L QAV RVNR +K+ G ++D L ++ + Y
Sbjct: 613 DAPSLTYLYIDKRMQDHGLFQAVCRVNRLDGEDKDFGCIIDYSDLFDSLQEAHSDYTNGA 672
Query: 770 -EMLARQDPKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSRIGIEVDILKAF 822
E R+D + L K ++ I +K+EE ++L+ + E + E D + F
Sbjct: 673 FENYEREDIQGLISDK---SQKIKKKLEETRDQLKSLCESVKEPKDEEDYIAYF 723
>emb|CAA68059.1| (X99719) Sty SBLI [Salmonella enterica]
Length = 1088
Score = 153 bits (382), Expect = 1e-35
Identities = 163/667 (24%), Positives = 285/667 (42%), Gaps = 99/667 (14%)
Query: 144 PDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKYERYSKPLFRF 203
PD L+ING+P+V+ E K+ + E E W ++ + Q+ Y
Sbjct: 167 PDAILYINGLPLVVFEFKS-AVREQEANIGDAWKQLCTRYRRDIPQLFVYNALC-----I 220
Query: 204 VQFGVAYGDKQLYTP-----TMPRDSGDAPASEWRYPNEDKPDIFDLLKPERLLDMLRHY 258
+ GV L+ P + + +G+ + P+ I L P RLLD+++++
Sbjct: 221 ISDGVNNRMGNLFAPYEYFYSWRKVTGNENREQNGIPSLHSM-IQGLFHPVRLLDVIKNF 279
Query: 259 TFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTFIMFFV 318
F K +K+ R+ QY AA+K+ IE+ + K G + G GK++ M F+
Sbjct: 280 ICFPDKAKHEVKICCRYPQYYAARKLYYSIERARKPFGDGKGGTYFGATGCGKSYTMQFL 339
Query: 319 ANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEI 378
+ + +P + I DR DL+DQ S + ++ + + S +LR++
Sbjct: 340 TRLLMKSVEFASPTIVLITDRTDLDDQLSAQMCNAKNYIGDDTVVPVTSRDDLREK---- 395
Query: 379 IESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEA 438
+ +G G+++TTI KF D E ++ I+ + DEA
Sbjct: 396 LAGRNSG-----GVFLTTIHKFTED------------------TELLSERSNIICISDEA 432
Query: 439 HRTQ-------------------YGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFA 479
HR+Q YG A + PR + GFTGTPI T F
Sbjct: 433 HRSQVNLDQKVIVDKESGRVRKTYG-FAKYLHDSLPRATYVGFTGTPI----DATMDVFG 487
Query: 480 YPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDV 539
+D Y +++S++D T+ IV+ E + LD KL+ Y+
Sbjct: 488 ------VIVDSYTMTESVQDEITVRIVY---EGRAAKVILDAGKLEEVEKYYEECANAGT 538
Query: 540 EAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVV 599
+ + KK + + + + + E FA++ KR+ + + KAM V
Sbjct: 539 NEWQIDESKKASATMNAILGDEDRLKALAED------FAKHYEKRVAEGST-VKGKAMFV 591
Query: 600 AVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQH 659
+RE F + L K++ + E + VE+ + +E + ++VMT
Sbjct: 592 CASREIAWDFYRQL----KDFRPAWFEVKQAPEGVELTGQEEKELPPSE-MVKMVMTRGK 646
Query: 660 NETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPIL 719
++ +++ + L +E++K+ L ++ K K+ IV DM LTGFD P L
Sbjct: 647 DDDAKLYD-----LLGSKEYRKE-------LDKQFKNAKSNFKIAIVVDMWLTGFDVPEL 694
Query: 720 RVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIYEMLARQDPKV 779
+Y+ KP+ +H L+Q ++RVNR K GLVVD +G+ ++ M +R D
Sbjct: 695 DTIYIDKPLQKHNLIQTISRVNRKMEGKSKGLVVDYIGIKR---QMNQALAMYSRIDATN 751
Query: 780 LEDFKRN 786
ED +++
Sbjct: 752 FEDIQQS 758
>pir||S49394 HsdR1 protein - Mycoplasma pulmonis >gi|496157|gb|AAA65632.1|
(L25415) restriction-modification enzyme subunit R1
[Mycoplasma pulmonis]
Length = 986
Score = 152 bits (379), Expect = 3e-35
Identities = 237/1078 (21%), Positives = 442/1078 (40%), Gaps = 224/1078 (20%)
Query: 82 EIRSKLASSGEVEMLEYIKY--GVPITVLGRHD-----KVILIDYDDPTNNIFFFLHEAK 134
+IR +L S+ + +Y G + ++D ++ +D+++ NN F+ L +
Sbjct: 56 DIRRELLSNNSASSYRFAQYLWGFDTVKIYKNDGPKKIRLKFVDWENWANNEFYVLQQFP 115
Query: 135 YPGFPENIKPDFS--LFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRK 192
N+ F + ING P+++ E K K E ++ +A+ QI +
Sbjct: 116 TRDAKNNMGKRFDSLILINGFPLILFEFKDKS----ENIN------------KAINQIDE 159
Query: 193 YERYS---KPLFRFVQF--GVAYGDKQLYTPTMPRDSGDAPASEWRYPN--EDKPDIFDL 245
R S K +FRF+Q G + + + ++ + +W N K I D
Sbjct: 160 SYRGSVLNKGIFRFIQILIGSNFEEVKFLANNKRTNNNKILSFKWTSENGGSSKELIKDF 219
Query: 246 LKPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGL--- 302
L L + L++Y F + D ++ R Q RA KK I +EK L + K+ L
Sbjct: 220 LNKNALEEYLKNYVVFQRSKDDEKIILLRPYQQRAIKKAINFVEKQLKTNLDAKHNLNNA 279
Query: 303 -IWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERH 361
IW GSGKT + +A L++ + +VF +VDR DL DQ S F+ +
Sbjct: 280 YIWHTTGSGKTLTSYKIAE-ILSKNSDIDHVVF-LVDRNDLNDQTSQTFQKLMSSSKNEK 337
Query: 362 FDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFE 421
D + + K + EI +E L ITTIQK + + K E
Sbjct: 338 IDFLNQ--DTSKDLYEIFLKKEK-------LIITTIQK-----------LNNILSSYKNE 377
Query: 422 AEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYP 481
+ + + +F+IDE HR+ G + ++ + GF+GTP
Sbjct: 378 KIEFLTNKKFVFIIDECHRSNAGLMGKRIKDFLNNSIMIGFSGTP--------------- 422
Query: 482 KDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAF---IDAYQLNDPED 538
+ EE D K F ID+Y + D
Sbjct: 423 ---------------------------IFEENN-----DRETQKIFGNEIDSYNMKDAI- 449
Query: 539 VEAFLMGRKKKLKMSSRELAEELRKSRVFLESPK----EIERFAEYIAKRIYDDTMGFSF 594
++ ++G K + +++R+F E+ +I+ I + D T ++
Sbjct: 450 LDKNVLGFK---------VVNYYQETRIFRENNNSNLGKIKSIINVIKSKHLDFTNNRNY 500
Query: 595 KAMVVAVN-REACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEV 653
+++ ++A + + M + F + I E + F L + E+ +
Sbjct: 501 NSIIAFDTIQDALTFYDEFYKMDVGDIFATPI--FSSYSNEEKNEKFFNLKEHKEK---I 555
Query: 654 VMTYQHN-ETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLT 712
+ Y+ TS +E+F K++ +++ K+Y+S N I ++IV DMLLT
Sbjct: 556 LKRYEEKFNTSFKVEDFDKYVNDV-QWRFKEYNSENNSI----------DIVIVVDMLLT 604
Query: 713 GFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYP-NKETGLVVDGVGLLPAVIRVKNIYE- 770
GFD+P +Y+ K + H L+QA +R NR +K+ G++V+ ++ IY
Sbjct: 605 GFDSPRTNTLYINKELKNHNLIQAFSRTNRLSDYSKKRGIIVNFSLEEQSINDAFKIYAN 664
Query: 771 ---------MLARQDPKVLEDF-------KRNFARSIDEKVEE------FENKLQKVKED 808
+ + +V+EDF K +F+ DEK E ENK +K ++
Sbjct: 665 SSDKEIQQLVYGEKYEQVVEDFINFWNSLKISFSNIYDEKNNEIFRNISLENK-KKYLKN 723
Query: 809 LSRIGIEVDILKAFKKQGRWKELE----AEMDRVRNILAPIALDFKGNEPKAVRLFNDLH 864
LS++ LK FK+ G+ +++ ++++ + I + NE + + +
Sbjct: 724 LSQVSNIFSSLKTFKEYGKNEKISDFSLEQLNQYQKWANEIKKNLSTNEKEKIS-----Y 778
Query: 865 EVISMYRSLGAHPAKLAYIDDMIVVGAIYSTFIRLIDFSRKKSKFWDDLLRFVHEHMEVG 924
EV++ S+ K AY + +++ IY L+ F++K SK+ ++ L + E+
Sbjct: 779 EVLN---SIDISNIKFAYKE--MIIDEIY--LENLLFFNKKISKYPNNRLTYEDTLSEID 831
Query: 925 PMRELIKVKLSEFSGGEASFEVVARFYKLYYTAEDNIHDPFYKAILERLNRLLEEWINRN 984
+LIK ++ + +E+ L+++W N
Sbjct: 832 KHIQLIKNNYNQGKINQKEYEIFL--------------------------LLVQKWKN-E 864
Query: 985 IDLKALRKQINILEGQIGEYEKKRAGKTWQESLLESVKFYVKNYLGLEGVEFKKFQRELK 1044
I ++K ++ E + +Y K+ +L+SV VKN +E + +K +E
Sbjct: 865 IKNFFIKKDKSLDEKEFIDYGKR---------ILKSVFQKVKNQ--IEAMWLEKILKEYH 913
Query: 1045 RLR--RLNPRTVKRLSSSLLDDIMEAIKDDNLNKYRELSKEIDRLVEESIIPEVRKHV 1100
+ ++ KR++ LDDI K + + K+ SKE+D+ + + + E ++ +
Sbjct: 914 GINNDQIRKDWKKRINDKDLDDIE---KSEFIKKWSRRSKEVDKDIIDKLSIEYKESI 968
>pir||T30329 hsdR protein - Klebsiella pneumoniae >gi|2411488|gb|AAB70710.1|
(U93843) HsdR [Klebsiella pneumoniae]
Length = 1102
Score = 150 bits (376), Expect = 6e-35
Identities = 188/790 (23%), Positives = 328/790 (40%), Gaps = 150/790 (18%)
Query: 144 PDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKYERYSKPLFRF 203
PD L+ING+P+V+ E K+ + E E + + ++ T +Y R LF +
Sbjct: 167 PDAILYINGLPLVVFEFKS-AVREQE-------ANIGDAYKQLCT---RYRRDIPQLFVY 215
Query: 204 -----VQFGVAYGDKQLYTPTMPRDSGDAPASEWRYPNEDKPDIFDLLK----PERLLDM 254
+ GV L+ P S + P + +++ P RLLD+
Sbjct: 216 NALCIISDGVNNRMGNLFAPYEYFYSWRKVTGNENREQDGIPSLHSMIQGLFHPVRLLDV 275
Query: 255 LRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTFI 314
++++ F K +K+ R+ QY A +K+ IE+ + K G + G GK++
Sbjct: 276 IKNFICFPDKAKHEVKICCRYPQYYAGRKLYYSIERARKPFGDGKGGTYFGATGCGKSYT 335
Query: 315 MFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKR 374
M F+ + + + R+P + I DR DL+DQ S + ++ + + S +LR++
Sbjct: 336 MQFLTRLLMKKRRVRSPTIVLITDRTDLDDQLSAQMCNAKNYIGDDTVVPVTSRDDLREK 395
Query: 375 IEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFL 434
+ +G G+++TTI KF D E + I+ +
Sbjct: 396 ----LAGRNSG-----GVFLTTIHKFTED------------------TELLSGRSNIICI 428
Query: 435 IDEAHRTQ-------------------YGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTF 475
DEAHR+Q YG A + P+ + GFTGTPI T
Sbjct: 429 SDEAHRSQVNLDQKVIVDKESGRVRKTYG-FAKYLYDSLPQATYVGFTGTPI----DATM 483
Query: 476 QEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLND 535
+ F +D Y +++S++D T+ IV+ E + LD KL+ Y+
Sbjct: 484 EVFG------NIVDSYTMTESVQDEITVRIVY---EGRAAKVILDTRKLEEVEKYYEECA 534
Query: 536 PEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFK 595
+ + KK + + + + E FA++ KR+ + + K
Sbjct: 535 NAGTNEWQIDESKKASATMNAILGDDDRLEALAED------FAKHYEKRVNEGST-VKGK 587
Query: 596 AMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVM 655
AM V +RE F + L K++ +E + VE+ + + +E + ++VM
Sbjct: 588 AMFVCASREIDWDFYRQL----KDFRPEWVEVKQAPDDVELTEQEEKELPPSE-MVKMVM 642
Query: 656 TYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFD 715
T ++ +++ E L +E++K+ L ++ K K+ IV DM LTGFD
Sbjct: 643 TRGKDDHAKLYE-----LLGSKEYRKE-------LDKQFKNAKSNFKIAIVVDMWLTGFD 690
Query: 716 APILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVG------------------ 757
P L +Y+ KP+ +H L+Q ++RVNR K GLVVD +G
Sbjct: 691 VPELDTIYIDKPLQKHNLIQTISRVNRKLEGKSKGLVVDYIGIKRQMNQALAMYSRIDAT 750
Query: 758 ----LLPAVIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVE--------EFENKLQKV 805
+ +VI VKN ++LA +VL DF S + + + EF + QK
Sbjct: 751 NFEDIQQSVIEVKNHLDLLA----QVLHDFDSRPYFSGEPQAQLACLNQAAEFVMRTQKT 806
Query: 806 KED----LSRIGIEVDILKAFKKQGRWKELEAEMDRVRNILAPIALDF---KGNEPKAVR 858
+ + R+ DI G +AE D + +A ++ F KG+ P +
Sbjct: 807 ERRFMGLVKRLKAAYDIC-----SGSESLSQAERDHIHFYIAVRSIVFKLTKGDAPDVTQ 861
Query: 859 LFNDLHEVIS 868
+ + E+I+
Sbjct: 862 MNARVREMIA 871
>gb|AAC25971.1| (AF003541) endonuclease (R) subunit homolog [Mycoplasma pulmonis]
Length = 986
Score = 147 bits (367), Expect = 7e-34
Identities = 236/1078 (21%), Positives = 440/1078 (39%), Gaps = 224/1078 (20%)
Query: 82 EIRSKLASSGEVEMLEYIKY--GVPITVLGRHD-----KVILIDYDDPTNNIFFFLHEAK 134
+IR +L S+ + +Y G + ++D ++ +D+++ NN F+ L +
Sbjct: 56 DIRRELLSNNSASSYRFAQYLWGFDTVKIYKNDGPKKIRLKFVDWENWANNEFYVLQQFP 115
Query: 135 YPGFPENIKPDFS--LFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRK 192
N+ F + ING P+++ E K K E ++ +A+ QI +
Sbjct: 116 TRDAKNNMGKRFDSLILINGFPLILFEFKDKS----ENIN------------KAINQIDE 159
Query: 193 YERYS---KPLFRFVQF--GVAYGDKQLYTPTMPRDSGDAPASEWRYPN--EDKPDIFDL 245
R S K +FRF+Q G + + + ++ + +W N K I D
Sbjct: 160 SYRGSVLNKGIFRFIQILIGSNFEEVKFLANNKRTNNNKILSFKWTSENGGSSKELIKDF 219
Query: 246 LKPERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGL--- 302
L L + L++Y F + D ++ R Q RA KK I +EK L + K+ L
Sbjct: 220 LNKNALEEYLKNYVVFQRSKDDEKIILLRPYQQRAVKKAINFVEKQLKTNLDAKHNLNNA 279
Query: 303 -IWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERH 361
IW GSGKT + +A L++ + +VF +VDR DL DQ S F+ +
Sbjct: 280 YIWHTTGSGKTLTSYKIAE-ILSKNSDIDHVVF-LVDRNDLNDQTSQTFQKLMSSSKNEK 337
Query: 362 FDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFE 421
D + + K + EI +E L ITTIQK + K E
Sbjct: 338 IDFLNQ--DTSKDLYEIFLKKEK-------LIITTIQKSN-----------NILSSYKNE 377
Query: 422 AEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYP 481
+ + + +F+IDE HR+ G + ++ + GF+GTP
Sbjct: 378 KIEFLTNKKFVFIIDECHRSNAGLMGKRIKDFLNNSIMIGFSGTP--------------- 422
Query: 482 KDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAF---IDAYQLNDPED 538
+ EE D K F ID+Y + D
Sbjct: 423 ---------------------------IFEENN-----DRETQKIFGNEIDSYNMKDAI- 449
Query: 539 VEAFLMGRKKKLKMSSRELAEELRKSRVFLESPK----EIERFAEYIAKRIYDDTMGFSF 594
++ ++G K + +++R+F E+ +I+ I + D T ++
Sbjct: 450 LDKNVLGFK---------VVNYYQETRIFRENNNSNLGKIKSIINVIKSKHLDFTNNRNY 500
Query: 595 KAMVVAVN-REACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEV 653
+++ ++A + + M + F + I E + F L + E+ +
Sbjct: 501 NSIIAFDTIQDALTFYDEFYKMDVGDIFATPI--FSSYSNEEKNEKFFNLKEHKEK---I 555
Query: 654 VMTYQHN-ETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLT 712
+ Y+ TS +E+F K++ +++ K+Y+S N I ++IV DM LT
Sbjct: 556 LKRYEEKFNTSFKVEDFDKYVNDV-QWRFKEYNSENNSI----------DIVIVVDMSLT 604
Query: 713 GFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYP-NKETGLVVDGVGLLPAVIRVKNIYE- 770
GFD+P +Y+ K + H L+QA +R NR +K+ G++V+ ++ IY
Sbjct: 605 GFDSPRTNTLYINKELKNHNLIQAFSRTNRLSDYSKKRGIIVNFSLEEQSINDAFKIYAN 664
Query: 771 ---------MLARQDPKVLEDF-------KRNFARSIDEKVEE------FENKLQKVKED 808
+ + +V+EDF K +F+ DEK E ENK +K ++
Sbjct: 665 SSDKEIQQLVYGEKYEQVVEDFINFWNSLKISFSNIYDEKNNEIFRNISLENK-KKYLKN 723
Query: 809 LSRIGIEVDILKAFKKQGRWKELE----AEMDRVRNILAPIALDFKGNEPKAVRLFNDLH 864
LS++ LK FK+ G+ +++ ++++ + I + NE + + +
Sbjct: 724 LSQVSNIFSSLKTFKEYGKNEKISDFSLEQLNQYQKWANEIKKNLSTNEKEKIS-----Y 778
Query: 865 EVISMYRSLGAHPAKLAYIDDMIVVGAIYSTFIRLIDFSRKKSKFWDDLLRFVHEHMEVG 924
EV++ S+ K AY + +++ IY L+ F++K SK+ ++ L + E+
Sbjct: 779 EVLN---SIVISNIKFAYKE--MIIDEIY--LENLLFFNKKISKYPNNRLTYEDTLSEID 831
Query: 925 PMRELIKVKLSEFSGGEASFEVVARFYKLYYTAEDNIHDPFYKAILERLNRLLEEWINRN 984
+LIK ++ + +E+ L+++W N
Sbjct: 832 KHIQLIKNNYNQGKINQKEYEIFL--------------------------LLVQKWKN-E 864
Query: 985 IDLKALRKQINILEGQIGEYEKKRAGKTWQESLLESVKFYVKNYLGLEGVEFKKFQRELK 1044
I ++K ++ E + +Y K+ +L+SV VKN +E + +K +E
Sbjct: 865 IKNFFIKKDKSLDEKEFIDYGKR---------ILKSVFQKVKNQ--IEAMWLEKILKEYH 913
Query: 1045 RLR--RLNPRTVKRLSSSLLDDIMEAIKDDNLNKYRELSKEIDRLVEESIIPEVRKHV 1100
+ ++ KR++ LDDI K + + K+ SKE+D+ + + + E ++ +
Sbjct: 914 GINNDQIRKDWKKRMNDKDLDDIE---KSEFIKKWSRRSKEVDKDIIDKLSIEHKESI 968
>pir||C81153 type I restriction enzyme EcoR124II R protein, probable NMB0835
[imported] - Neisseria meningitidis (group B strain
MD58) >gi|7226069|gb|AAF41246.1| (AE002436) type I
restriction enzyme EcoR124II R protein, putative
[Neisseria meningitidis MC58]
Length = 921
Score = 127 bits (315), Expect = 9e-28
Identities = 184/764 (24%), Positives = 307/764 (40%), Gaps = 125/764 (16%)
Query: 110 RHDKVILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELE 169
R + L+D + N +++ + G N + D ++ +NG+P+V IE K +G+
Sbjct: 6 RLKNIYLLDKKNLARNHVQVINQFEQTGTHAN-RYDVTVLVNGLPLVQIELKKRGV---- 60
Query: 170 EVDWRRWSKVHGTEEEALTQIRKYERYS----KPLFRFVQ-FGVAYG-DKQLYTPTMPRD 223
EA Q+ +Y + S LF+F+Q F ++ G D + + T RD
Sbjct: 61 ------------AVREAFNQVHRYSKESFNSENSLFKFLQIFVISNGTDTRYFANTTKRD 108
Query: 224 --SGDAPASEWRYPNEDKPDIFDL----LKPERLLDMLRHYTFFFKKNDGRIKVIARWNQ 277
S D + R N D+ D L+ LL +L HY+ F ND + I R Q
Sbjct: 109 KNSFDFTMNWARSDNHPIKDLKDFTATFLQKSVLLGVLLHYSVF-DANDTLL--IMRPYQ 165
Query: 278 YRAAKKIIKRIEKYLSRESEKK---NGLIWQWQGSGKTFIMFFVANW-----FLNRYKKR 329
AA++I+ +I ++ K G +W GSGKT F A F+++
Sbjct: 166 IAAAERILWKINSSAQAKNWSKPESGGYVWHTTGSGKTLTSFKAARLATESAFIDK---- 221
Query: 330 NPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIP 389
VFF+VDR DL+ Q +E++R + SE ++ +E ++ I+
Sbjct: 222 ---VFFVVDRKDLDYQTM--------KEYQRFSPDSVNGSESTAGLKRNLEKDDNKIIV- 269
Query: 390 TGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAV 449
TTIQK +KGE+ V ++F+ DE HR+Q+G
Sbjct: 270 -----TTIQKLN----------NLMKGEDNLP----VYHQRVVFIFDECHRSQFGEAQKN 310
Query: 450 MRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEV 509
++ F + FGFTGTPIF + + A E L Y I+D+IRD
Sbjct: 311 LKKKFKKFCQFGFTGTPIFPENALGAETTAGVFGRE--LHSYVITDAIRD---------- 358
Query: 510 IEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLE 569
E+ + +D + ++ A + E KKL + A L
Sbjct: 359 --EKVLKFKVDYNDVRPQFKAVEAEQDE----------KKLSAAENHKA---------LL 397
Query: 570 SPKEIERFAEYIAKRIYDDTM-----GFSFKAMVVAVNREACVHFKKALDMAFKEYFCSK 624
P+ I +YI + T G F AM + +A K AFK
Sbjct: 398 HPERIREITQYILNQFRQKTHRLNAGGKGFNAMFAVSSVDAA----KCYYEAFKTQQAGS 453
Query: 625 IEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHNETSE-----VIEEFKKWLKTRREF 679
+ L+ A + E E + E + +++ I ++ KT
Sbjct: 454 LHPLKVATIFSFAAN-EEQNAVGEIVDETFEPEAMDSSAKEFLQAAINDYNACFKTNFGT 512
Query: 680 QKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTR 739
K + + R + + + ++ +LIV M LTGFDAP L +++ K + H L+QA +R
Sbjct: 513 DSKAFQNYYRDLAKRVKNQEID-LLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLMQAFSR 571
Query: 740 VNRPYPNKET-GLVVDGVGLLPAVIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVEEF 798
NR Y +T G +V L A I ++ ++ + + ++ D + E
Sbjct: 572 TNRIYDATKTFGNIVCFRDLEQATIDAITLFGDKNTKNVVLEKSYEEYMNGYTDSQTGEA 631
Query: 799 ENKLQKVKEDLSRIGIEVDILKAFKKQGRWKELEAEMDRVRNIL 842
V ++L + D ++ K + + +L E R N+L
Sbjct: 632 RRGYLDVAKELRERFPDPDKIETEKDKKDFAKLFGEYLRAENVL 675
>sp|P10486|T1R1_ECOLI TYPE I RESTRICTION ENZYME ECOR124II R PROTEIN (R.ECOR124II)
>gi|78918|pir||S02168 type I site-specific
deoxyribonuclease (EC 3.1.21.3) EcoR124/3 chain hsdR -
Escherichia coli plasmid R124/3
>gi|4467404|emb|CAA31543.1| (X13145) hsdR protein (AA
1-1033) [Escherichia coli]
Length = 1033
Score = 125 bits (311), Expect = 3e-27
Identities = 190/815 (23%), Positives = 322/815 (39%), Gaps = 165/815 (20%)
Query: 110 RHDKVILIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELE 169
R + + LID + N + + + G N + D ++ +NG+P+V IE K +G+
Sbjct: 117 RLENIYLIDKKNLMRNKVQIIQQFEQAGSHAN-RYDVTILVNGLPLVQIELKKRGV---- 171
Query: 170 EVDWRRWSKVHGTEEEALTQIRKYERYS----KPLFRFVQ-FGVAYG-DKQLYTPTMPRD 223
EA QI +Y + S LF+++Q F ++ G D + + T RD
Sbjct: 172 ------------AIREAFNQIHRYSKESFNSENSLFKYLQLFVISNGTDTRYFANTTKRD 219
Query: 224 SGDAPASEWRYPNEDKPDIFDL-------LKPERLLDMLRHYTFFFKKNDGRIKVIARWN 276
+ + D I DL + LL++L +Y+ F + + ++ R
Sbjct: 220 KNSFDFT-MNWAKSDNTLIKDLKDFTATCFQKHTLLNVLVNYSVF---DSSQTLLVMRPY 275
Query: 277 QYRAAKKIIKRIEKYLSRESEKK---NGLIWQWQGSGKTFIMFFVANW-----FLNRYKK 328
Q A ++I+ +I+ + ++ K G IW GSGKT F A F+++
Sbjct: 276 QIAATERILWKIKSSFTAKNWSKPESGGYIWHTTGSGKTLTSFKAARLATELDFIDK--- 332
Query: 329 RNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRII 388
VFF+VDR DL+ Q +E++R + SE ++ ++ ++ I+
Sbjct: 333 ----VFFVVDRKDLDYQTM--------KEYQRFSPDSVNGSENTAGLKRNLDKDDNKIIV 380
Query: 389 PTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAA 448
T ++K+ K E++ V +++F+ DE HR+Q+G
Sbjct: 381 TT--------------------IQKLNNLMKAESDLPVYNQQVVFIFDECHRSQFGEAQK 420
Query: 449 VMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYFLDVYFISDSIRD----GFTLD 504
++ F R FGFTGTPIF + + A E L Y I+D+IRD F +D
Sbjct: 421 NLKKKFKRYYQFGFTGTPIFPENALGSETTASVFGRE--LHSYVITDAIRDEKVLKFKVD 478
Query: 505 IVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKS 564
+ + + DE KL A E+ +AFL
Sbjct: 479 YNDVRPQFKSLETETDEKKLSA---------AENQQAFL--------------------- 508
Query: 565 RVFLESPKEIERFAEYI-------AKRIYDDTMGFSFKAMVVAVNREACVH--FKKALDM 615
P I+ +YI R + + GF+ V +V+ + FK+ +
Sbjct: 509 -----HPMRIQEITQYILNNFRQKTHRTFPGSKGFNAMLAVSSVDAAKAYYATFKRLQEE 563
Query: 616 AFKE---YFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHNE-TSEVIEEFKK 671
A + Y +I + E E+ + E M E I E+
Sbjct: 564 AANKSATYKPLRIATIFSFAANEEQNAIGEI--SDETFDTSAMDSSAKEFLDAAIREYNS 621
Query: 672 WLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILRVMYLYKPIFEH 731
KT + + R + + + +D +LIV M LTGFDAP L +++ K + H
Sbjct: 622 HFKTNFSTDSNGFQNYYRDLAQRVKNQDI-DLLIVVGMFLTGFDAPTLNTLFVDKNLRYH 680
Query: 732 RLLQAVTRVNRPYPNKET-GLVVDGVGLLPAVI---------RVKNIYEMLARQDPKVLE 781
L+QA +R NR Y +T G +V L + I KN+ +L + + +E
Sbjct: 681 GLMQAFSRTNRIYDATKTFGNIVTFRDLERSTIDAITLFGDKNTKNV--VLEKSYTEYME 738
Query: 782 DF--------KRNFARSIDEKVEEFEN--KLQKVKEDLSRIGIEVDILKAFKKQGRWKEL 831
F KR F + E + F + ++ KE + D +K F + R + +
Sbjct: 739 GFTDAATGEAKRGFMTVVSELEQRFPDPTSIESEKE-------KKDFVKLFGEYLRAENI 791
Query: 832 EAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEV 866
D + A +D ++P AV F H V
Sbjct: 792 LQNYDEFATLKALQQIDL--SDPVAVEKFKAEHYV 824
>gi|10956196 type IC restriction subunit [Streptococcus thermophilus]
>gi|11356443|pir||T44802 type I site-specific
deoxyribonuclease (EC 3.1.21.3) chain hsdR [imported] -
Streptococcus thermophilus plasmid pER35
>gi|6137147|gb|AAF04356.1| (AF177167) type IC restriction
subunit [Streptococcus thermophilus]
Length = 1025
Score = 122 bits (302), Expect = 3e-26
Identities = 208/993 (20%), Positives = 391/993 (38%), Gaps = 178/993 (17%)
Query: 145 DFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKY--ERYSKPLFR 202
D SL ING+PI+ IE K + + +A QI++Y + + K ++
Sbjct: 135 DVSLLINGLPIIHIELKKESAKD--------------GFMQAYYQIQRYAEDGFFKGIYA 180
Query: 203 FVQFGVAYGDKQL-YTPTMPRDSGDAPAS------EWRYP-NEDKPDIFD----LLKPER 250
Q V Y D+ +A A WR N+ D+FD +L+
Sbjct: 181 TTQIMVISNKVDTRYFARPSEDTAEAYARMKKFLFNWRTEDNQTVSDLFDFTRTVLRIPD 240
Query: 251 LLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSG 310
+++ YT + K + Y+ I I K + ++ + G IW GSG
Sbjct: 241 AHELISQYTILVDDQKNQ-KFLMALRPYQ-----IHAIRKIRQKAAQHEGGFIWHATGSG 294
Query: 311 KTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDR------ 364
KT I FVA L + +VDR DL+ Q + F E H +
Sbjct: 295 KT-ITSFVATKLLAQNAIGVDRTVMVVDRTDLDAQTQDEFTKFAS---EYHTGQTTENSV 350
Query: 365 ----IRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKF 420
I I ++ + ++ S+ I+ +TTIQK + + + KG +F
Sbjct: 351 ANTLIVGIKNQKQLAQNLLSSKNNNTIL-----VTTIQKLSA-AMRSAQQESEEKGSNQF 404
Query: 421 EAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIF----KRDRNTFQ 476
E +++ I+F++DEAHR ++ + P +FG TGTPIF K++ TF
Sbjct: 405 EK---LRQEHIVFIVDEAHRAVSDEEMKRIKKILPNSTWFGLTGTPIFEENKKQENGTFA 461
Query: 477 EFAYPKDGEYFLDVYFISDSIRDGFTLDI---VHEVIEEEGVSIALDE-SKLKAFIDAYQ 532
+ G L Y I +++ DG L H +I EE + + + +K K DA Q
Sbjct: 462 RTTSQQYGP-LLHSYTIKNAMDDGAVLGFQVEYHSLISEEDQEVIVTQLNKGKLPDDALQ 520
Query: 533 LNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGF 592
+ K+ EL E R L+ + F + + GF
Sbjct: 521 ----------------QEKLLPTELYETDEHIRTMLQ-----KIFNRRSVVKKFKVKNGF 559
Query: 593 SFKAMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAER-LS 651
+ ++ + +A ++ ++E++ +G + + F E + ++
Sbjct: 560 PTMSAILTTH-----------SIAQAKHIYRILKEMKDNGTLLNGRQFDERHQLIDKDFP 608
Query: 652 EVVMTY-----------QHNETSEVIEEFKKWLKTRREFQKKDYD-SINRLIVEWFQEKD 699
V +T+ Q +E E+++E++K +K Y+ +IN+ + +EK
Sbjct: 609 RVAITFSTNPDQLEKNEQDDELVEIMKEYEKQFDASPYQDEKLYNQNINKRLAR--KEKQ 666
Query: 700 YPK------VLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVV 753
Y +IV D LLTGFD+P ++ +Y+ + + +LLQA +R NR Y K++GL+V
Sbjct: 667 YQSDGQWLDFVIVVDRLLTGFDSPTIQTLYIDREMNYQKLLQAFSRTNRIYTGKDSGLIV 726
Query: 754 DGVGLLPAVIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSRIG 813
+ + P + + RN R + + F+ + K E++ +
Sbjct: 727 -------------------SFRKPFTMRENVRNTFRLFSNEKQNFDQLIPKEYEEVKKEF 767
Query: 814 IEVDILKAFKKQGRWKELEAEMDRVRNILAPIALDFKGNEP-----KAVRLFN----DLH 864
IE L +K+ EA++ N L + + KA+R ++ D
Sbjct: 768 IECSTL--------YKQSEADLSDNPNDLKTMIAQVSAYQKLEKSYKALRSYDQYEEDFE 819
Query: 865 EVISMYRSLGAHPAKL--------AYIDDMIVVGAIYSTFIRLIDFSRKKSKFWDDLLRF 916
E + L + K I+D + ++ I FS + + D++
Sbjct: 820 EFSEVVEQLPQYQGKTENIKTKIKEMIEDEGHPEEDFEKLLQEIAFSSQLNATHKDVVDS 879
Query: 917 VHEHMEVGPMRELIKVKLSEFSGGEASFEVV-----ARFYKLYYTAEDNIHDPFYKAILE 971
+ + +L+K +G FE + K+Y+T +D + + + +
Sbjct: 880 FY-------INQLLKAIQLNEAGAVEKFEKEIQQKDPQIQKMYHTLKDQLVNTTEEIDVA 932
Query: 972 RLNRL-LEEWINRNIDLKA--LRKQINILEGQIGEYEKKRAGKTWQESLLESVKFYVKNY 1028
+L ++ I R + +A + L+ + EY+ + + LL+S+ + +
Sbjct: 933 QLKETSIQNEIQRQLQKEAEEFGLSFDFLQSAMNEYQSDKKTIPYLTHLLDSMTLSKEEF 992
Query: 1029 LGLEGVEFKKFQRELKRLRRLNPRTVKRLSSSL 1061
G ++++ + L+ + N +++ L
Sbjct: 993 EAKTGEKYRRRTKVLEERLQQNFEQLQKWKEEL 1025
>pir||T09459 type I site-specific deoxyribonuclease (EC 3.1.21.3) LldI chain
hsdR - Lactococcus lactis subsp. lactis plasmid pND861
>gi|2689698|gb|AAB91415.1| (AF034786) restriction
subunit [Lactococcus lactis bv. diacetylactis]
Length = 1025
Score = 121 bits (301), Expect = 4e-26
Identities = 186/820 (22%), Positives = 331/820 (39%), Gaps = 124/820 (15%)
Query: 35 EMVSKYSGLEDSLGDFVLWNVLERKIRELNRAFFDN--LTEEEEEKVWGEIRSKLASSGE 92
E ++++ D + LW + +N A + LT++E ++V E +
Sbjct: 18 EKENQWTYRPDLKSEEALWQNFRGHLNRINLAVLEEQLLTDKEFKQVKVEFSRLTGTPFL 77
Query: 93 VEMLEYIKYGVPITVLGRHD--KVILIDYDDPTNNIFFFLHEAKYPGFPENIKPD---FS 147
+ GV +L R D KV L + + + +E + P++ + D S
Sbjct: 78 ASQWLRGENGVAQVLLEREDGKKVTLEAFRNKDISGGTSSYEVVHQVVPDSSRVDRGDVS 137
Query: 148 LFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKY--ERYSKPLFRFVQ 205
L ING+PI+ IE K + + +A QI++Y + + K ++ Q
Sbjct: 138 LLINGLPIIHIELKKESAKD--------------GFMQAYYQIQRYAEDGFFKGIYATTQ 183
Query: 206 FGVAYGDKQL-YTPTMPRDSGDAPAS------EWRYP-NEDKPDIFD----LLKPERLLD 253
V Y D+ +A A WR N+ D+FD +L+ +
Sbjct: 184 IMVISNKVDTRYFARPSEDTAEAYARMKKFLFNWRTEDNQTVSDLFDFTRTVLRIPDAHE 243
Query: 254 MLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTF 313
++ YT + K + Y+ I I K + ++ + G IW GSGKT
Sbjct: 244 LISQYTILVDDQKNQ-KFLMALRPYQ-----IHAIRKIRQKAAQHEGGFIWHATGSGKT- 296
Query: 314 IMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRK 373
I FVA L + +VDR DL+ Q + F E H + S
Sbjct: 297 ITSFVATKLLAQNAIGVDRTVMVVDRTDLDAQTQDEFTKFAS---EYHTGQTTGNSVANT 353
Query: 374 RIEEIIESEETGRIIPTG-----LYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKK 428
I I ++ R + + + +TTIQK + + + KG +FE +++
Sbjct: 354 LIVGIKNQKQLARNLLSSKNNNTILVTTIQKLSA-AMRSAQQESEEKGSNQFEK---LRQ 409
Query: 429 PEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIF----KRDRNTFQEFAYPKDG 484
I+F++DEAHR ++ + P +FG TGTPIF K++ TF + G
Sbjct: 410 EHIVFIVDEAHRAVSDEEMKRIKKILPNSTWFGLTGTPIFEANKKQENGTFARTTSQQYG 469
Query: 485 EYFLDVYFISDSIRDGFTLDI---VHEVIEEEGVSIALDE-SKLKAFIDAYQLNDPEDVE 540
L Y +++ DG L H +I EE + + + +K K DA Q
Sbjct: 470 P-LLHSYTTKNAMDDGAVLGFQVEYHSLISEEDQEVIVTQLNKGKLPDDALQ-------- 520
Query: 541 AFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVA 600
+ K+ EL E R L+ + F + + GF + ++
Sbjct: 521 --------QEKLLPTELYETDEHIRTMLQ-----KIFNRRSVVKKFKVKNGFPTMSAILT 567
Query: 601 VNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAER-LSEVVMTY-- 657
+ +A ++ ++E++ +G + + F E + ++ V +T+
Sbjct: 568 TH-----------SIAQAKHIYRILKEMKDNGTLLNGRQFDERHQLIDKDFPRVAITFST 616
Query: 658 ---------QHNETSEVIEEFKKWLKTRREFQKKDYD-SINRLIVEWFQEKDYPK----- 702
Q +E E+++E+ K +K Y+ +IN+ + +EK Y
Sbjct: 617 NPDQLEKNEQDDELVEIMKEYAKQFDASPYQDEKLYNQNINKRLAR--KEKQYQSDGQWL 674
Query: 703 -VLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPA 761
+IV D LLTGFD+P ++ +Y+ + + +LLQA +R NR Y K++GL+V
Sbjct: 675 DFVIVVDRLLTGFDSPTIQTLYIDREMNYQKLLQAFSRTNRIYTGKDSGLIVSFRKPFTM 734
Query: 762 VIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVEEFENK 801
VKN + + + + K+NF + I ++ EE + +
Sbjct: 735 KENVKNTFRLFSNE--------KQNFDQLIPKEYEEVKKE 766
>gb|AAF69137.1|AF228680_1 (AF228680) HsdR [Lactococcus lactis]
>gi|9789462|gb|AAF98314.1|AF243383_15 (AF243383) HsdR
[Lactococcus lactis subsp. lactis]
Length = 1025
Score = 121 bits (301), Expect = 4e-26
Identities = 186/820 (22%), Positives = 331/820 (39%), Gaps = 124/820 (15%)
Query: 35 EMVSKYSGLEDSLGDFVLWNVLERKIRELNRAFFDN--LTEEEEEKVWGEIRSKLASSGE 92
E ++++ D + LW + +N A + LT++E ++V E +
Sbjct: 18 EKENQWTYRPDLKSEEALWQNFRGHLNRINLAVLEEQLLTDKEFKQVKVEFSRLTGTPFL 77
Query: 93 VEMLEYIKYGVPITVLGRHD--KVILIDYDDPTNNIFFFLHEAKYPGFPENIKPD---FS 147
+ GV +L R D KV L + + + +E + P++ + D S
Sbjct: 78 ASQWLRGENGVAQVLLEREDGKKVTLEAFRNKDISGGTSSYEVVHQVVPDSSRVDRGDVS 137
Query: 148 LFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKY--ERYSKPLFRFVQ 205
L ING+PI+ IE K + + +A QI++Y + + K ++ Q
Sbjct: 138 LLINGLPIIHIELKKESAKD--------------GFMQAYYQIQRYAEDGFFKGIYATTQ 183
Query: 206 FGVAYGDKQL-YTPTMPRDSGDAPAS------EWRYP-NEDKPDIFD----LLKPERLLD 253
V Y D+ +A A WR N+ D+FD +L+ +
Sbjct: 184 IMVISNKVDTRYFARPSEDTAEAYARMKKFLFNWRTEDNQTVSDLFDFTRTVLRIPDAHE 243
Query: 254 MLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSGKTF 313
++ YT + K + Y+ I I K + ++ + G IW GSGKT
Sbjct: 244 LISQYTILVDDQKNQ-KFLMALRPYQ-----IHAIRKIRQKAAQHEGGFIWHATGSGKT- 296
Query: 314 IMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISELRK 373
I FVA L + +VDR DL+ Q + F E H + S
Sbjct: 297 ITSFVATKLLAQNAIGVDRTVMVVDRTDLDAQTQDEFTKFAS---EYHTGQTTGNSVANT 353
Query: 374 RIEEIIESEETGRIIPTG-----LYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKK 428
I I ++ R + + + +TTIQK + + + KG +FE +++
Sbjct: 354 LIVGIKNQKQLARNLLSSKNNNTILVTTIQKLSA-AMRSAQQESEEKGSNQFEK---LRQ 409
Query: 429 PEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIF----KRDRNTFQEFAYPKDG 484
I+F++DEAHR ++ + P +FG TGTPIF K++ TF + G
Sbjct: 410 EHIVFIVDEAHRAVSDEEMKRIKKILPNSTWFGLTGTPIFEANKKQENGTFARTTSQQYG 469
Query: 485 EYFLDVYFISDSIRDGFTLDI---VHEVIEEEGVSIALDE-SKLKAFIDAYQLNDPEDVE 540
L Y +++ DG L H +I EE + + + +K K DA Q
Sbjct: 470 P-LLHSYTTKNAMDDGAVLGFQVEYHSLISEEDQEVIVTQLNKGKLPDDALQ-------- 520
Query: 541 AFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVA 600
+ K+ EL E R L+ + F + + GF + ++
Sbjct: 521 --------QEKLLPTELYETDEHIRTMLQ-----KIFNRRSVVKKFKVKNGFPTMSAILT 567
Query: 601 VNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAER-LSEVVMTY-- 657
+ +A ++ ++E++ +G + + F E + ++ V +T+
Sbjct: 568 TH-----------SIAQAKHIYRILKEMKDNGTLLNGRQFDERHQLIDKDFPRVAITFST 616
Query: 658 ---------QHNETSEVIEEFKKWLKTRREFQKKDYD-SINRLIVEWFQEKDYPK----- 702
Q +E E+++E+ K +K Y+ +IN+ + +EK Y
Sbjct: 617 NPDQLEKNEQDDELVEIMKEYAKQFDASPYQDEKLYNQNINKRLAR--KEKQYQSDGQWL 674
Query: 703 -VLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPA 761
+IV D LLTGFD+P ++ +Y+ + + +LLQA +R NR Y K++GL+V
Sbjct: 675 DFVIVVDRLLTGFDSPTIQTLYIDREMNYQKLLQAFSRTNRIYTGKDSGLIVSFRKPFTM 734
Query: 762 VIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVEEFENK 801
VKN + + + + K+NF + I ++ EE + +
Sbjct: 735 KENVKNTFRLFSNE--------KQNFDQLIPKEYEEVKKE 766
>pir||T30322 type I site-specific deoxyribonuclease (EC 3.1.21.3) LldI chain hsdR
- Lactococcus lactis plasmid pIL2614
>gi|2865242|gb|AAC15896.1| (U90222) type IC restriction
subunit [Lactococcus lactis]
Length = 1025
Score = 116 bits (289), Expect = 1e-24
Identities = 207/980 (21%), Positives = 390/980 (39%), Gaps = 152/980 (15%)
Query: 145 DFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKY--ERYSKPLFR 202
D SL ING+PI+ IE + + + +A QI++Y + + K ++
Sbjct: 135 DVSLLINGLPIIHIELQKESAKD--------------GFMQAYYQIQRYAEDGFFKGIYA 180
Query: 203 FVQFGVAYGDKQL-YTPTMPRDSGDAPAS------EWRYP-NEDKPDIFD----LLKPER 250
Q V Y D+ +A A WR N+ D+FD +L+
Sbjct: 181 TTQIMVIPNKVDTRYFARPSEDTAEAYARMKKFLFNWRTEDNQTVSDLFDFTRTVLRIPD 240
Query: 251 LLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQWQGSG 310
+++ YT + K + Y+ I I K + ++ + G IW GSG
Sbjct: 241 AHELISQYTILVD-DPKNPKFLMALRPYQ-----IHAIRKIRPKAAQHEGGFIWHATGSG 294
Query: 311 KTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSISE 370
KT I FVA L + +VDR DL+ Q + F E H + S
Sbjct: 295 KT-ITSFVATKLLAQNAIGVDRTVMVVDRTDLDAQTQDEFTKFAS---EYHTGQTTGNSV 350
Query: 371 LRKRIEEIIESEETGRIIPTG-----LYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKA 425
I I ++ R + + + +TTIQK + + + KG +FE
Sbjct: 351 ANTLIVGIKNQKQLARNLLSSKNNNTILVTTIQKLSA-AMRSAQQESEEKGSNQFEK--- 406
Query: 426 VKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIF----KRDRNTFQEFAYP 481
+++ I+F++DEAHR ++ + P +FG TGTPIF K++ TF
Sbjct: 407 LRQEHIVFIVDEAHRAVSDEEMKRIKKILPNSTWFGLTGTPIFEANKKQENGTFARTTSQ 466
Query: 482 KDGEYFLDVYFISDSIRDGFTLDI---VHEVIEEEGVSIALDE-SKLKAFIDAYQLNDPE 537
+ G L Y +++ DG L H +I EE + + + + +K K DA Q +
Sbjct: 467 QYGP-LLHSYTTKNAMDDGAVLGFQVEYHSLISEEDLEVIVTQLNKGKLPGDALQQEE-- 523
Query: 538 DVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAM 597
+ EL E+ R L+ + F + + GF +
Sbjct: 524 --------------LLPAELYEKDEHIRTMLQ-----KIFNRRSVVKKFKVKNGFPTMSA 564
Query: 598 VVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAER-LSEVVMT 656
++ + +A ++ ++E++ +G + + F E R ++ V +T
Sbjct: 565 ILTTH-----------SIAQAKHIYRILKEMKDNGTLLNGRQFDERHRLIDKDFPRVAIT 613
Query: 657 Y-----------QHNETSEVIEEFKKWLKTRREFQKKDYD-SINRLIVEWFQEKDYPK-- 702
+ Q +E E+++E+ K +K Y+ +IN+ + +EK Y
Sbjct: 614 FSTNPDRLEKNEQDDELVEIMKEYAKQFDASPYQDEKLYNQNINKRLAR--KEKQYQSDG 671
Query: 703 ----VLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGL 758
+IV D LLTGFD+P + +Y+ + + +LLQA +R NR Y K++GL+V
Sbjct: 672 QWLDFVIVVDRLLTGFDSPAILTLYIDREMNYQKLLQAFSRTNRIYTGKDSGLIVSFRKP 731
Query: 759 LPAVIRVKNIYEMLARQD-------PKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSR 811
V+N + + + ++ P+ E+ K+ F ++ E L DL
Sbjct: 732 FTMKENVQNTFRLFSNENQNFDQLIPREYEEVKKEFI-ECSTLYKQSEADLSDNPHDLKT 790
Query: 812 IGIEVDILKAFKKQGRWKELEAEMDRVRNILAPIALDFKGNEPKAVRLFNDLHEVISMYR 871
+ +V A++K G+ + D+ DF+ F+++ E + YR
Sbjct: 791 MIAQV---SAYQKLGKSYKAFRSYDQYEE-------DFEA--------FSEVVEQLPQYR 832
Query: 872 SLGAH-PAKL-AYIDDMIVVGAIYSTFIRLIDFSRKKSKFWDDLLRFVHEHMEVGPMREL 929
+ K+ I+D + ++ I FS + + D++ + + +L
Sbjct: 833 GKTENVKTKIKEMIEDEEHPEEDFEKLLQEIAFSSQLNATHKDVVDSFY-------INQL 885
Query: 930 IKVKLSEFSGGEASFEVV-----ARFYKLYYTAEDNIHDPFYKAILERLNRL-LEEWINR 983
+K +G FE + K+Y+T +D + + + + +L ++ I R
Sbjct: 886 LKAIQLNEAGAVEKFEKEIQQKDPQIQKMYHTLKDQLVNTTEEIDVAQLKETSIQNEIQR 945
Query: 984 NIDLKA--LRKQINILEGQIGEYEKKRAGKTWQESLLESVKFYVKNYLGLEGVEFKKFQR 1041
+ +A + L+ + EY+ + + LL+S+ + + G ++++ +
Sbjct: 946 LLQKEAEEFGLSFDFLQSAMNEYQGDKKAIPYLTHLLDSMTLSKEEFEPKAGEKYRRRPK 1005
Query: 1042 ELKRLRRLNPRTVKRLSSSL 1061
L+ R N +++ L
Sbjct: 1006 VLEERLRQNFEQIQKWKEEL 1025
>pir||B71890 type I restriction enzyme (restriction chain) - Helicobacter pylori
(strain J99) >gi|4155340|gb|AAD06353.1| (AE001508) TYPE
I RESTRICTION ENZYME (RESTRICTION SUBUNIT) [Helicobacter
pylori J99]
Length = 875
Score = 112 bits (277), Expect = 3e-23
Identities = 158/653 (24%), Positives = 266/653 (40%), Gaps = 141/653 (21%)
Query: 130 LHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQ 189
+H+ G + D S+ +NG+P+V +E K +G+ EA Q
Sbjct: 4 IHQYSNKGGKYENRYDVSVLVNGLPLVHVELKKRGV----------------AIREAFNQ 47
Query: 190 IRKYERYS----KPLFRFVQ-FGVAYGDKQLY---TPTMPRDSGDAPASEWRYPN----- 236
I++Y+R S LF FVQ F ++ G Y T + + + A + + N
Sbjct: 48 IKRYKRDSFSAEDGLFEFVQIFVISNGTSSKYYSNTTRIAQIEKNNKADTFEFTNYWADS 107
Query: 237 --EDKPDIFDLLKP----ERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEK 290
+ D+ D K LL++L Y F + + ++ R Q AA++I+++I+
Sbjct: 108 KNRNIEDLMDFAKSFFAKRSLLNVLTRYCVFTSEE---VLLVMRPYQIVAAERILEKIKA 164
Query: 291 YLSRESEKKN---GLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHS 347
++ K+ G IW GSGKT F A L + + V F+VDR DL+ Q
Sbjct: 165 THDSKTYGKSQSGGYIWHTTGSGKTLTSFKSAT--LAKELEHVSKVLFVVDRKDLDYQTM 222
Query: 348 NIFESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKD 407
++ +F++ + +++ K+ E ++ + ITTIQK DKF
Sbjct: 223 KEYD-----KFQKDCANSNTSTKILKQQLEDFNAK---------IIITTIQKL--DKF-- 264
Query: 408 MVRVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPI 467
VK K A + E++ + DE HR+Q G + + F + FGFTGTPI
Sbjct: 265 ------VKAHLKGHA---IFNEEVVMIFDECHRSQLGSMHQAITKAFKKYHLFGFTGTPI 315
Query: 468 FKR--DRNTFQEFAYPKDGEYFLDVYFISDSIRD----GFTLDIVHEVIEEEGVSIALDE 521
F + D+N K G L Y I D+IRD F ++ + + +EG+ D+
Sbjct: 316 FAQNCDKNNPLGTTEQKFGR-CLHQYTIIDAIRDKNVLPFRVEYHNTIKAKEGIK---DK 371
Query: 522 SKLKAFIDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYI 581
+K D E + K L S R I+ A+ I
Sbjct: 372 EGIK------------DKEVRAVDEKNALLDSRR------------------IKEIAKCI 401
Query: 582 AKRIYDDTMGFSFKAMVVAVNREACVHFKKAL-----DMAFKEYFC----SKIEELEKDG 632
+R + T F +++ EA + +A D+ F +IE LE +
Sbjct: 402 LERFHQATKNKKFNSILACSGIEALKKYYQAFKEEKHDLKIATIFSYSANEEIEALEDEN 461
Query: 633 KVEMA---KHFRELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINR 689
A K R+ A I ++ + + + + S +
Sbjct: 462 NESTAGLDKSSRDFLEGA------------------IADYNGMFQISFDTSDQKFQSYYK 503
Query: 690 LIVEWFQEKDYPKVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNR 742
+ + +E++ +L+V +M LTGFDA L +++ K + H L+QA +R NR
Sbjct: 504 DLSQKMKEREI-DLLLVANMFLTGFDATRLNTLWVDKNLKYHGLIQAFSRTNR 555
>pir||F82522 type I restriction-modification system endonuclease XF2725
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9107961|gb|AAF85510.1|AE004079_1 (AE004079) type I
restriction-modification system endonuclease [Xylella
fastidiosa]
Length = 1007
Score = 111 bits (275), Expect = 4e-23
Identities = 197/832 (23%), Positives = 333/832 (39%), Gaps = 144/832 (17%)
Query: 105 ITVLGRHDKVI----LIDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEA 160
+ VL R D I L+D + NNI +++ G N + D ++ +NG+P+V +E
Sbjct: 115 VQVLKRDDGTIKNMCLLDKGNIHNNILQVMNQYAVEGARGN-RYDVTVLVNGLPMVHVEL 173
Query: 161 KAKGIIELEEVDWRRWSKVHGTEEEALTQIRKYERYS----KPLFRFVQFGV-------- 208
K +G VD R EA QI +Y+R S LF +VQ V
Sbjct: 174 KRRG------VDIR----------EAFNQINRYQRDSFWAGSGLFDYVQLFVISNGTLTK 217
Query: 209 --------AYGDKQLYTPTMPRDSGDAPASEWRYPNEDKP--DIFDLLK----PERLLDM 254
+ ++Q + + S + W +++P ++ K LL++
Sbjct: 218 YYSNTVRAGHVEEQSNKRSKSKTSNSFSFAIWWADAKNQPITELTSFTKTFFAKHSLLNV 277
Query: 255 LRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEKYLSRE---SEKKNGLIWQWQGSGK 311
L Y F N R ++ R Q AA++I++RI ++ + G IW GSGK
Sbjct: 278 LTKYCVF---NANRKLLVMRPYQIVAAERILQRIVTATHQQQLGTVAAGGYIWHTTGSGK 334
Query: 312 TFIMFFVANWF--LNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDREFERHFDRIRSIS 369
T F VA L K V F+VDR DL+ Q +ES E + S +
Sbjct: 335 TLTSFKVAQLACGLGVIDK----VLFVVDRKDLDYQTMREYESFEKGAANSN----TSTA 386
Query: 370 ELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEKAVKKP 429
L++++E + RII ITTIQK +F V K K + A AV
Sbjct: 387 VLQRQLE-----DSDVRII-----ITTIQKL--SRF-----VAKHKQHPVYGAHVAV--- 426
Query: 430 EILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFKRDRNTFQEFAYPKDGEYF-- 487
+ DE HR+Q+G + + F R FGFTGTPIF + + Q + F
Sbjct: 427 ----IFDECHRSQFGDMHTEITRAFQRYHLFGFTGTPIFAENAGSTQNPMRRTTQQTFGD 482
Query: 488 -LDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQLNDPEDVEAFLMGR 546
L Y I D+I D L + I +++ ++ A L PE +
Sbjct: 483 TLHTYTIVDAINDKTVLPFRIDYINTIKSQPNINDKQVAAIDTERALLAPERI------- 535
Query: 547 KKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDTMGFSFKAMVVAVNREAC 606
++ + ++ +++ ++ + ++ F +A D + + M +
Sbjct: 536 RQIVSYIREHFDQKTKRASIYRHEGQRLQGFNALLATASIDAAKRYYAELMAQQKDLPEA 595
Query: 607 VHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNAERLSEVVMTYQHNETSEVI 666
K L + E DG +A+ E ERL + N I
Sbjct: 596 QRLKVGL--------IYSVAANEGDGDELLAEEEFE----TERLDQDA----RNFLEAAI 639
Query: 667 EEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVTDMLLTGFDAPILRVMYLYK 726
+++ T + + + + + E +++ +LIV +M LTGFDA L +++ K
Sbjct: 640 QDYNALFGTSFDTSADKFQNYYKDVSERLKKRKL-DILIVVNMFLTGFDATTLNTLWVDK 698
Query: 727 PIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNIYEMLARQDPKVLEDFKRN 786
+ H L+QA +R NR +++ V ++ +N L ++ + L F
Sbjct: 699 RLKAHGLIQAYSRTNR---------ILNSVKSYGNIVSFRN----LEQETNEALALFGNK 745
Query: 787 FARSI------DEKVEEFENKLQKVKE--DLSRIGIEVDILKAFKKQGRWKELEAEMDRV 838
A+ I E +E+E ++ ++ L ++ + KAF L + R+
Sbjct: 746 DAKGIVLLRPYAEYYKEYEERVGELVAAFPLGKVIVGEAAQKAF------ITLFGSILRL 799
Query: 839 RNILAPIALDFKGNEPKAVRLFNDLHEV-ISMYRSL-GAHPAKLAYIDDMIV 888
+NIL DF G E R F D + +++Y A A+ I+D +V
Sbjct: 800 KNILTAFD-DFAGQEVLTEREFQDYQSLYLNLYAEFRSASAAEKESINDDVV 850
>pir||H82934 type I restriction enzyme R protein UU095 [imported] - Ureaplasma
urealyticum >gi|6899049|gb|AAF30501.1|AE002109_4
(AE002109) type I restriction enzyme R protein
[Ureaplasma urealyticum]
Length = 1045
Score = 108 bits (268), Expect = 3e-22
Identities = 176/791 (22%), Positives = 317/791 (39%), Gaps = 141/791 (17%)
Query: 145 DFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQIRKYERYS-KPLFRF 203
D S+ ING+P+V IE K +G +EA QI++Y +S L+ +
Sbjct: 154 DVSILINGLPLVHIELKRRGT----------------NLKEAFNQIKRYANHSFTDLYLY 197
Query: 204 VQ-FGVAYGDKQLYTPTMPRDSGDAPASEWRYPNEDKP-DIFDLL------KPERLLDML 255
Q + ++ G + Y R++ E N K + F+ K ++LD++
Sbjct: 198 TQIYVISNGTQTKYYSNTTRETS---IKERNNTNSKKTSNSFEFTSYWADSKNNQILDLI 254
Query: 256 RHYTFFFKKN--------------DGRIKVIARWNQYRAAKKIIKRIEKYLSRE----SE 297
FF K+ D + V+ + Q A ++II RI+ L+ + +
Sbjct: 255 DFCQTFFAKHTILNILTKYCVFTSDNTLMVLRPY-QIVATERIINRIKISLNDKKLLGTT 313
Query: 298 KKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNIFESVEDRE 357
G IW GSGKT F A L + + V F+VDR DL+ Q + +E
Sbjct: 314 GAGGYIWHTTGSGKTLTSFKTAA--LAKEIEGVDKVLFVVDRKDLDYQTTKEYEKYSKGC 371
Query: 358 FERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGE 417
+ +++EL K+I + +II ITTIQK K+
Sbjct: 372 VSAN----TNVNELAKQI-----GNQENKII-----ITTIQKLGIFISKN---------- 407
Query: 418 EKFEAEKAVKKPEILFLIDEAHRTQYGRL-AAVMRALFPRGMFFGFTGTPIFKRDRNTFQ 476
+ + ++ + DE HR+Q+G L + + F + M FGFTGTPI + + N
Sbjct: 408 ----PKHPIYSKNVVLVFDECHRSQFGDLHKKITKKSFKKYMIFGFTGTPILEENSNVKN 463
Query: 477 EFAYPKDGEYF---LDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAFIDAYQ- 532
+ + F L Y I +IRDG L E + +D+ ID +
Sbjct: 464 KNIFFTTEHLFGACLHKYTIDKAIRDGNVLGFRTEYYKTLSEKDDIDDETSSTGIDKKEA 523
Query: 533 LNDP---EDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYDDT 589
L +P ++ F++ +L + E E + + + + I + ++
Sbjct: 524 LENPIRISEIVDFILKNYNRLTKRNEEFFEHNKIANI----NEVITSRNKLSENKVLTTL 579
Query: 590 MGFSFKAMVVAVNREACVH--FKKALDMAFKEYFCSKIEEL------EKDGKVEMAKHFR 641
GF+ ++N + FKK F + KI + E++ +F
Sbjct: 580 NGFNSILACSSINAAKIYYSEFKKQ-QQKFPQEEKLKIGLIYSYLPSEQESNDNELSNFE 638
Query: 642 ELCRNAERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYP 701
L N E +++ + N E I+++ + T ++++ + +++
Sbjct: 639 LLDENNENTNQLDLD-SRNFLDEAIKDYNEMFGTSYSTDNANFNNYYKDFSLRLKDRSL- 696
Query: 702 KVLIVTDMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPA 761
+ IV +M LTGFDA L ++L K + H L+QA++R NR +++GV
Sbjct: 697 DIAIVVNMFLTGFDATTLNTLWLDKKLKYHSLIQAMSRTNR---------ILNGVKSNGN 747
Query: 762 VIRVKNIYEMLARQDPKVLEDFKRNFARSIDEKVEEFENKLQKVKEDLSRIGIEVDILKA 821
++ F N ++E + F ++ S I + IL++
Sbjct: 748 IV-------------------FFINLEDEVNEALRLFSSE--------SNINSSIAILRS 780
Query: 822 FKK--QGRWKELEAEMDRVRNILAPIALDFK---GNEPKAVRLFNDLHEVISMYRSLGAH 876
FK+ +G + E + RN++ + +FK + R+F L I Y++L +
Sbjct: 781 FKEYYEGYYNEDNQYIQGYRNLVEELKSNFKIPFNGTKEEERIFIKLFGDILKYKNLLSQ 840
Query: 877 PAKLAYIDDMI 887
++ DD+I
Sbjct: 841 FSEFEQNDDLI 851
>pir||F64625 type I restriction enzyme R protein - Helicobacter pylori (strain
26695) >gi|2313977|gb|AAD07892.1| (AE000595) type I
restriction enzyme R protein (hsdR) [Helicobacter pylori
26695]
Length = 866
Score = 108 bits (268), Expect = 3e-22
Identities = 150/635 (23%), Positives = 259/635 (40%), Gaps = 114/635 (17%)
Query: 130 LHEAKYPGFPENIKPDFSLFINGIPIVIIEAKAKGIIELEEVDWRRWSKVHGTEEEALTQ 189
+H+ G + D S+ +NG+P+V +E K +G+ EA Q
Sbjct: 4 IHQYSNKGGKYQNRYDVSILVNGLPLVHVELKKRGV----------------AIREAFNQ 47
Query: 190 IRKYERYS----KPLFRFVQ-FGVAYGDKQLY---TPTMPRDSGDAPASEWRYPN----- 236
I++Y+R S LF FVQ F ++ G Y T + + + A + + N
Sbjct: 48 IKRYKRDSFSAEDGLFDFVQIFVISNGTSSKYYSNTTRIAQLEKNHKADTFEFTNYWADS 107
Query: 237 --EDKPDIFDLLKP----ERLLDMLRHYTFFFKKNDGRIKVIARWNQYRAAKKIIKRIEK 290
+ D+ D K LL++L Y F + + ++ R Q AA++I+++I+
Sbjct: 108 KNHNIEDLMDFAKAFFAKRSLLNVLTCYCVFTSEE---VLLVMRPYQIVAAERILEKIKT 164
Query: 291 YL-SRESEKKNGLIWQWQGSGKTFIMFFVANWFLNRYKKRNPIVFFIVDRIDLEDQHSNI 349
S+ + G IW GSGKT F A L + + V F+VDR DL+ Q
Sbjct: 165 AQNSKTKNQSKGYIWHTTGSGKTLTSFKSAT--LAKELESVSKVLFVVDRKDLDYQTM-- 220
Query: 350 FESVEDREFERHFDRIRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMV 409
+E+++ + + K ++E +E + +II ITTIQK DKF
Sbjct: 221 ------KEYDKFQKDCANSNTSTKILKEQLE-DSNAKII-----ITTIQKL--DKF---- 262
Query: 410 RVRKVKGEEKFEAEKAVKKPEILFLIDEAHRTQYGRLAAVMRALFPRGMFFGFTGTPIFK 469
V+ KG A+ E++ + DE HR+Q G + + F + FGFTGTPIF
Sbjct: 263 -VKSHKGH-------AIFNEEVVMIFDECHRSQLGSMHQAITKAFKKYHLFGFTGTPIFA 314
Query: 470 R--DRNTFQEFAYPKDGEYFLDVYFISDSIRDGFTLDIVHEVIEEEGVSIALDESKLKAF 527
D+N K G+ L Y I D+IRD L E + ++K++A
Sbjct: 315 ANCDKNNPLGTTEQKFGK-CLHQYTIIDAIRDKNVLPFRVEYHNTIKAKEDIKDNKVRAV 373
Query: 528 IDAYQLNDPEDVEAFLMGRKKKLKMSSRELAEELRKSRVFLESPKEIERFAEYIAKRIYD 587
+ L D ++ K L+ ++ + S + S + ++++ + + +D
Sbjct: 374 DEKNALLDTRRIKEI---TKCILERFNQATKNKKFNSILACSSIEALKKYYQAFKEEKHD 430
Query: 588 DTMGFSFKAMVVAVNREACVHFKKALDMAFKEYFCSKIEELEKDGKVEMAKHFRELCRNA 647
+ F + N E +E+ + + K R+ A
Sbjct: 431 LKIAAIFS---YSANEE-----------------IDTLEDENNESACRLDKSSRDFLEGA 470
Query: 648 ERLSEVVMTYQHNETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPKVLIVT 707
+ + + + + + K L + + +K D +L+V
Sbjct: 471 IADYNGMFGVSFDTSDQKFQSYYKDLSQKMKERKID-------------------LLMVV 511
Query: 708 DMLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNR 742
+M LTGFDA L +++ K + H L+QA +R NR
Sbjct: 512 NMFLTGFDATRLNTLWVDKNLKYHGLIQAFSRANR 546
>gb|AAG22017.1|AF288038_2 (AF288038) putative HsdR [Streptococcus thermophilus]
Length = 740
Score = 96.0 bits (235), Expect = 2e-18
Identities = 110/454 (24%), Positives = 199/454 (43%), Gaps = 99/454 (21%)
Query: 117 IDYDDPTNNIFFFLHEAKYPGFPENIKPDFSLFINGIPIVIIEAK--------------- 161
+D+++P NN F E + +PD +FING+P+ IE K
Sbjct: 99 VDWENPENNTFHLALEVTCQNGGDEFRPDIVIFINGLPLSYIEVKQPNAIRDGKTAIQSE 158
Query: 162 -AKGIIELEEVDWRRWSKV-------------HGTEEEALTQIRKYERYSKPLFRFVQFG 207
++ + E +RR++ + G ++ +SK +F F
Sbjct: 159 QSRTAVRFENRRFRRFNNITQLISFSDNLPYISGQGQQKQGSFYCSNAFSKT--KFNAFK 216
Query: 208 VAYGDKQLYT-PTMPRDSGDAPASEW-RYPNEDKPD--------------IFDLLKPERL 251
++ +Y+ ++ + DA + R+ + +P+ I L + +RL
Sbjct: 217 EEREEELIYSIRSLGEEEIDAVLKDVNRFALKSQPEFKTNQDPSTPCNTFISSLYQKKRL 276
Query: 252 LDMLRHYTFFFKKN--DGRIKV---IARWNQYRAAKKIIKRIEKYLSRESEKKNGLIWQW 306
L +LR+ + +++ DG I++ + R+ Q+ A K I I K + + G+IW
Sbjct: 277 LFLLRYGLAYVEEHSKDGTIQLQKHVMRYPQFFATKAIEDAIGKGV------RKGVIWHT 330
Query: 307 QGSGKTFIMFFVANWFLNRYKKRN--PIVFFIVDRIDLEDQHSNIFESVEDREFERHFDR 364
QGSGKT + +F + N + K+ P +F+VDR+DL DQ + REF + +
Sbjct: 331 QGSGKTALSYFNIRYLTNYFSKQGIVPQFYFVVDRLDLADQAT--------REFTKRGLK 382
Query: 365 IRSISELRKRIEEIIESEETGRIIPTGLYITTIQKFQYDKFKDMVRVRKVKGEEKFEAEK 424
++ I+ +E+ E + ++ + IQ KFKD + G +
Sbjct: 383 VKRINS----PQELNEKHDAYQVA-----VVNIQ-----KFKDNSDLTDHSGYD------ 422
Query: 425 AVKKPEILFLIDEAHRTQYGRLAAVMRALF---PRGMFFGFTGTPI--FKRDRNTFQEFA 479
+ ++ IDEAHR+ Y + + L+ + TGTP+ +K+D T + A
Sbjct: 423 --LNRQNIYFIDEAHRS-YNEKGSYLPNLYNADKNAIKIALTGTPLITYKKDGKTKESHA 479
Query: 480 YPKD--GEYFLDVYFISDSIRDGFTLDIVHEVIE 511
+D G+Y + Y+ + SI DGFTL ++ E IE
Sbjct: 480 TTRDIFGDY-IHKYYYNQSIDDGFTLRLMREDIE 512
Score = 70.6 bits (170), Expect = 9e-11
Identities = 50/158 (31%), Positives = 79/158 (49%), Gaps = 16/158 (10%)
Query: 661 ETSEVIEEFKKWLKTRREFQKKDYDSINRLIVEWFQEKDYPK------------VLIVTD 708
++S+ E +K L+ RR + + + + LI+ +K+Y K ++IV
Sbjct: 574 DSSKQAREIEKQLEERRS--RGETNITSALILHDEGDKEYKKDRVESYREGKIDLVIVYS 631
Query: 709 MLLTGFDAPILRVMYLYKPIFEHRLLQAVTRVNRPYPNKETGLVVDGVGLLPAVIRVKNI 768
MLLTGFDAP L+ +YL + I H LLQ +TRVNRPY + + G V+D + +
Sbjct: 632 MLLTGFDAPRLKRLYLGRKIKAHNLLQTLTRVNRPYKDYQFGYVIDFADISKEFDKTNRA 691
Query: 769 Y--EMLARQDPKVLEDFKRNFARSIDEKVEEFENKLQK 804
Y E+ DPK + N S+ +E +L+K
Sbjct: 692 YLEELNQEYDPKNTGEDVENVFGSLFVSADEISKQLEK 729
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.140 0.406
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 410967223
Number of Sequences: 2977
Number of extensions: 18334810
Number of successful extensions: 60993
Number of sequences better than 1.0e-10: 30
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 60788
Number of HSP's gapped (non-prelim): 76
length of query: 1104
length of database: 189,106,746
effective HSP length: 58
effective length of query: 1046
effective length of database: 154,394,500
effective search space: 161496647000
effective search space used: 161496647000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 170 (70.6 bits)