BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2177 (fabG-like) DE:PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCTASE
(263 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75217 probable short-chain dehydrogenase/reductase PAB2177... 516 e-145
pir||C71204 probable dehydrogenase - Pyrococcus horikoshii >gi|3... 494 e-139
pir||H72686 probable dehydrogenase APE0912 - Aeropyrum pernix (s... 240 2e-62
gb|AAK42438.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 233 2e-60
pir||D72285 3-oxoacyl-(acyl carrier protein) reductase - Thermot... 168 5e-41
gb|AAG20295.1| (AE005104) putative oxidoreductase; OxrA [Halobac... 160 1e-38
emb|CAC11951.1| (AL445065) 3-oxoacyl-[acyl-carrier-protein] redu... 160 2e-38
gb|AAK41248.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 152 5e-36
sp|O67610|FABG_AQUAE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 146 3e-34
dbj|BAB18775.1| (AB045131) NADPH-dependent retinol dehydrogenase... 144 9e-34
gi|10337605 peroxisomal short-chain alcohol dehydrogenase [Homo ... 144 9e-34
dbj|BAA91953.1| (AK001870) unnamed protein product [Homo sapiens] 144 9e-34
gi|11433956 peroxisomal short-chain alcohol dehydrogenase [Homo ... 141 8e-33
pir||D75472 oxidoreductase, short-chain dehydrogenase/reductase ... 141 1e-32
dbj|BAB18776.1| (AB045132) NADPH-dependent retinol dehydrogenase... 139 2e-32
pir||T22676 hypothetical protein F54F3.4 - Caenorhabditis elegan... 139 3e-32
dbj|BAB18777.1| (AB045133) NADPH-dependent retinol dehydrogenase... 137 1e-31
dbj|BAB06210.1| (AP001515) 3-oxoacyl-(acyl-carrier protein) redu... 137 1e-31
emb|CAB59447.1| (AL132644) putative oxidoreductase [Streptomyces... 137 2e-31
pir||T32002 hypothetical protein F36H9.3 - Caenorhabditis elegan... 136 3e-31
gb|AAK43217.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 134 8e-31
sp|Q13268|HE27_HUMAN HEP27 PROTEIN (PROTEIN D) 130 2e-29
gi|5031737 short-chain alcohol dehydrogenase family member [Homo... 130 2e-29
emb|CAB58301.1| (AL121854) putative oxidoreductase [Streptomyces... 129 5e-29
pir||E81695 3-oxoacyl-(acyl carrier protein) reductase TC0508 [i... 128 8e-29
gb|AAC44307.1| (U59433) 3-ketoacyl-acyl carrier protein reductas... 127 2e-28
sp|P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 125 4e-28
pir||C75151 oxidoreductase PAB0245 - Pyrococcus abyssi (strain O... 125 4e-28
sp|P50941|FABG_RICPR 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 125 4e-28
pir||D72377 oxidoreductase, short chain dehydrogenase/reductase ... 124 1e-27
gb|AAF51983.1| (AE003602) CG2907 gene product [Drosophila melano... 123 2e-27
sp|O54438|FABG_PSEAE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 123 3e-27
sp|P38004|FABG_CHLTR 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 123 3e-27
pir||A83207 probable short-chain dehydrogenase PA3507 [imported]... 122 6e-27
sp|P37440|UCPA_ECOLI OXIDOREDUCTASE UCPA >gi|7427657|pir||A65017... 121 8e-27
gb|AAF50801.1| (AE003567) CG10672 gene product [Drosophila melan... 121 1e-26
emb|CAA68181.1| (X99908) belongs to alcohol dehydrogenase /rybit... 121 1e-26
sp|P43713|FABG_HAEIN 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 120 2e-26
dbj|BAA36159.1| (AB009078) L-2.3-butanediol dehydrogenase [Brevi... 120 2e-26
gb|AAC38801.1| (AF030176) putative short-chain dehydrogenase/red... 119 3e-26
dbj|BAB04651.1| (AP001510) 3-oxoacyl-(acyl-carrier protein) redu... 118 5e-26
emb|CAB65876.1| (AL109630) /match=(desc:""3-OXOACYL-[ACYL-CARRIE... 118 7e-26
gb|AAG34187.1|AF321122_6 (AF321122) Sim-nJ1 [Streptomyces antibi... 118 7e-26
pir||A71192 probable glucose 1-dehydrogenase - Pyrococcus horiko... 117 1e-25
pir||G75333 3-oxoacyl-acyl carrier protein reductase - Deinococc... 117 1e-25
pir||F81971 probable 3-oxoacyl-[acyl-carrier protein] reductase ... 117 1e-25
pir||H83476 probable short-chain dehydrogenase PA1344 [imported]... 116 2e-25
sp|P39644|YWFH_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PTA-ROCC INT... 115 4e-25
pir||H70046 probable 3-oxoacyl-[acyl-carrier-protein] reductase ... 115 4e-25
pir||A72395 oxidoreductase, short chain dehydrogenase/reductase ... 115 6e-25
sp|P25716|FABG_ECOLI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 115 7e-25
pir||E81026 3-oxoacyl-(acyl-carrier-protein) reductase NMB1921 [... 115 7e-25
sp|O85141|FABG_SALTY 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 114 1e-24
sp|P55336|FABG_VIBHA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 113 2e-24
pir||E70027 probable 3-oxoacyl-[acyl-carrier-protein] reductase ... 113 2e-24
gb|AAA23739.1| (M84991) 3-ketoacyl-acyl carrier protein reductas... 113 2e-24
gb|AAF51985.1| (AE003602) CG11005 gene product [Drosophila melan... 113 2e-24
emb|CAB60468.1| (AL132856) probable oxidoreductase [Streptomyces... 113 2e-24
sp|Q9X248|FABG_THEMA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 113 3e-24
sp|Q48436|BUDC_KLEPN ACETOIN(DIACETYL) REDUCTASE (ACETOIN DEHYDR... 112 5e-24
gb|AAA65204.1| (L35560) daunorubicin-doxorubicin polyketide synt... 111 6e-24
gb|AAC78679.1| (AF098800) acetoin reductase [Klebsiella pneumoniae] 111 9e-24
pir||F82128 3-oxoacyl-(acyl-carrier-protein) reductase VC2021 [i... 111 9e-24
sp|P50199|GNO_GLUOX GLUCONATE 5-DEHYDROGENASE (5-KETO-D-GLUCONAT... 111 9e-24
sp|P25529|HDHA_ECOLI 7-ALPHA-HYDROXYSTEROID DEHYDROGENASE (7-ALP... 111 1e-23
pir||S54815 urdamycin polyketide ketoreductase (EC 1.1.1.-) - St... 111 1e-23
sp|P73574|FAG1_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 111 1e-23
gb|AAF67503.1|AF170880_10 (AF170880) NovJ [Streptomyces spheroides] 111 1e-23
sp|Q9X6U2|BDHA_ALCEU D-BETA-HYDROXYBUTYRATE DEHYDROGENASE (BDH) ... 110 2e-23
gb|AAF89246.1|AF284419_2 (AF284419) 3-oxoacyl-(acyl carrier prot... 110 2e-23
pir||F83134 probable short-chain dehydrogenase PA4089 [imported]... 110 2e-23
gb|AAG03071.1|AF293355_7 (AF293355) putative reductase [Streptom... 109 3e-23
sp|P17611|NODG_AZOBR NODULATION PROTEIN G >gi|1070431|pir||DEKCN... 109 3e-23
pir||E70881 probable fabG5 protein - Mycobacterium tuberculosis ... 109 3e-23
gb|AAD32035.1|AF093787_3 (AF093787) CylG [Streptococcus agalactiae] 109 3e-23
pir||H75616 oxidoreductase, short-chain dehydrogenase/reductase ... 109 3e-23
emb|CAC11337.1| (AL445063) probable glucose 1-dehydrogenase [The... 109 4e-23
dbj|BAA13547.1| (D88156) tropinone reductase-I [Hyoscyamus niger... 108 6e-23
sp|P50164|TRN2_HYONI TROPINONE REDUCTASE-II (TR-II) >gi|425150|g... 108 7e-23
gb|AAB36565.1| (AF126429) ketoreductase [Streptomyces venezuelae] 108 7e-23
sp|Q9Z8P2|FABG_CHLPN 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 108 7e-23
sp|Q9WYG0|Y325_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0325 >gi|7431... 108 7e-23
gb|AAD42688.1|AF037323_1 (AF037323) D-beta-hydroxybutyrate dehyd... 108 1e-22
emb|CAB52307.1| (AJ245634) tropinone reductase II [Solanum tuber... 108 1e-22
gb|AAF51984.1| (AE003602) CG12171 gene product [Drosophila melan... 108 1e-22
gb|AAF74785.1|AF270650_1 (AF159243) 3-oxoacyl-(acyl carrier prot... 108 1e-22
dbj|BAA98195.1| (AP002030) short chain alcohol dehydrogenase-lik... 108 1e-22
pir||D55587 griseusin polyketide ketoreductase (EC 1.1.1.-) - St... 107 1e-22
sp|P50842|KDUD_BACSU 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE (2-KETO... 107 1e-22
gb|AAD05259.1| (AF109909) 3-ketoacyl-CoA reductase PhaB [Bacillu... 107 1e-22
gb|AAG29782.1|AF235050_5 (AF235050) CumE [Streptomyces rishirien... 107 1e-22
sp|P28643|FABG_CUPLA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 107 2e-22
gi|4503301 2,4-dienoyl CoA reductase 1 precursor; 4-enoyl-CoA re... 106 2e-22
pir||T36779 probable 3-oxacyl-(acyl-carrier-protein) reductase -... 106 2e-22
emb|CAB88214.1| (AJ400815) putative tropinone reductase [Solanum... 106 2e-22
gi|11427254 2,4-dienoyl CoA reductase 1, mitochondrial [Homo sap... 106 2e-22
sp|P55575|Y4MP_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYDROGENASE/RED... 106 4e-22
emb|CAA74371.1| (Y14043) glucose-1-dehydrogenase [Staphylococcus... 106 4e-22
emb|CAB61800.1| (AL133236) putative dehydrogenase [Streptomyces ... 106 4e-22
gb|AAK42782.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 105 5e-22
sp|P39640|YWFD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PTA-ROCC INT... 105 5e-22
sp|P57432|FABG_BUCAI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 105 5e-22
pir||S11021 2,4-dienoyl-CoA reductase (NADPH) (EC 1.3.1.34) - rat 105 6e-22
emb|CAB95803.1| (AL359949) putative short chain oxidoreductase [... 105 6e-22
pir||E82748 tropinone reductase XF0913 [imported] - Xylella fast... 105 6e-22
sp|P50162|TRN1_DATST TROPINONE REDUCTASE-I (TR-I) (TROPINE DEHYD... 104 8e-22
emb|CAB51900.1| (Y19033) 1,3,6,8-tetrahydroxynaphthalene reducta... 104 8e-22
dbj|BAB05886.1| (AP001514) 2-deoxy-D-gluconate 3-dehydrogenase [... 104 8e-22
sp|P50161|VER1_ASPPA VERSICOLORIN REDUCTASE (VER-1) >gi|1592833|... 104 1e-21
gb|AAC48769.1| (U71200) acetoin reductase [Bos taurus] 104 1e-21
pir||F75557 oxidoreductase, short-chain dehydrogenase/reductase ... 104 1e-21
emb|CAB59826.1| (AJ012388) diacetyl(acetoin) reductase [Lactococ... 104 1e-21
gi|10047132 oxidoreductase UCPA [Homo sapiens] >gi|8895083|gb|AA... 104 1e-21
pir||B70569 hypothetical protein Rv3485c - Mycobacterium tubercu... 103 2e-21
gb|AAF81239.1| (AF263012) putative beta-ketoacyl reductase [Stre... 103 2e-21
pir||F82776 3-oxoacyl-[ACP] reductase XF0671 [imported] - Xylell... 103 2e-21
pir||A48950 aflatoxin biosynthesis protein Ver-1 - Aspergillus p... 102 3e-21
sp|Q00791|STCU_EMENI VERSICOLORIN REDUCTASE >gi|1235633|gb|AAC49... 102 3e-21
gb|AAF18285.1| (AF088897) hypothetical protein; orf3 [Zymomonas ... 102 3e-21
gb|AAB65780.1| (AF002014) acetoacetyl-CoA reductase [Alcaligenes... 102 4e-21
gb|AAD10276.1| (U47026) acetoacetyl-CoA reductase, NADPH-linked ... 102 4e-21
gi|11437246 oxidoreductase UCPA [Homo sapiens] 102 4e-21
gb|AAB62288.1| (U24215) 2,3-dihydroxy-2,3-dihydro-p-cumate dehyd... 102 6e-21
pir||JC5856 polyketide synthase (EC 2.-.-.-) chain 7 - Actinomad... 102 6e-21
sp|P39482|DHG1_BACME GLUCOSE 1-DEHYDROGENASE I (GLCDH-I) >gi|801... 101 7e-21
sp|P72332|NODG_RHIS3 NODULATION PROTEIN G >gi|1531618|gb|AAB1689... 101 1e-20
pir||T36782 probable gluconate dehydrogenase - Streptomyces coel... 101 1e-20
sp|P50163|TRN2_DATST TROPINONE REDUCTASE-II (TR-II) >gi|539027|p... 101 1e-20
sp|P50205|PHBB_RHIME ACETOACETYL-COA REDUCTASE >gi|790552|gb|AAA... 101 1e-20
pir||T44434 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1... 101 1e-20
sp|P40288|DHG_BACME GLUCOSE 1-DEHYDROGENASE >gi|98132|pir||A3352... 100 2e-20
emb|CAA05517.1| (AJ002527) glucitol-6-phosphate dehydrogenase [C... 100 2e-20
sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) >gi|2... 100 3e-20
pir||F70677 hypothetical protein Rv3549c - Mycobacterium tubercu... 99 5e-20
sp|P06234|NODG_RHIME NODULATION PROTEIN G (HOST-SPECIFICITY OF N... 98 8e-20
emb|CAB69765.1| (AL137187) putative dehydrogenase/reductase [Str... 98 8e-20
gi|8923752 peroxisomal trans 2-enoyl CoA reductase; putative sho... 98 8e-20
gb|AAG30942.1| (AF314502) glucose dehydrogenase [Bacillus subtilis] 98 8e-20
gb|AAA87616.1| (L34880) polyketide reductase [Streptomyces sp.] 98 1e-19
gb|AAD38447.1|AF099742_1 (AF099742) putative short-chain dehydro... 98 1e-19
gb|AAF05857.1|AC011698_8 (AC011698) putative short-chain type de... 98 1e-19
sp|P23238|PHBB_ZOORA ACETOACETYL-COA REDUCTASE >gi|95026|pir||S0... 98 1e-19
sp|P39484|DHG3_BACME GLUCOSE 1-DEHYDROGENASE III (GLCDH-III) >gi... 98 1e-19
emb|CAC11396.1| (AL445063) 3-ketoacyl-acyl carrier protein reduc... 98 1e-19
sp|P80869|DHG2_BACSU GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) (GDH-... 97 2e-19
sp|P39485|DHG4_BACME GLUCOSE 1-DEHYDROGENASE IV (GLCDH-IV) >gi|2... 97 2e-19
sp|P10528|DHGA_BACME GLUCOSE 1-DEHYDROGENASE A >gi|80114|pir||S0... 96 3e-19
sp|O07575|YHDF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN CITA-SSPB IN... 96 3e-19
dbj|BAB09479.1| (AB012246) Brn1-like protein [Arabidopsis thaliana] 96 3e-19
emb|CAB58271.1| (AL121849) putative dehydrogenase [Streptomyces ... 96 4e-19
sp|P12310|DHG_BACSU GLUCOSE 1-DEHYDROGENASE >gi|7430990|pir||D69... 96 5e-19
gb|AAF69800.1|AF232011_1 (AF232011) peroxisomal trans 2-enoyl Co... 96 5e-19
pir||G82644 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogena... 96 5e-19
sp|P50197|LINC_PSEPA 2,5-DICHLORO-2,5-CYCLOHEXADIENE-1,4-DIOL DE... 95 7e-19
sp|Q11020|Y07E_MYCTU PUTATIVE OXIDOREDUCTASE RV1350 >gi|7431079|... 95 7e-19
pir||F75374 probable ketoacyl reductase - Deinococcus radioduran... 95 7e-19
gb|AAF69798.1|AF232009_1 (AF232009) peroxisomal trans 2-enoyl Co... 95 7e-19
gb|AAF69799.1|AF232010_1 (AF232010) peroxisomal trans 2-enoyl Co... 95 7e-19
pir||S01227 glucose 1-dehydrogenase (EC 1.1.1.47) B - Bacillus m... 95 9e-19
pir||S34724 probable oxidoreductase (EC 1.1.1.-) - Serratia marc... 95 9e-19
emb|CAC11810.1| (AL445065) polyketide synthase chain 7 related p... 95 9e-19
emb|CAC11888.1| (AL445065) glucose 1-dehydrogenase related prote... 95 9e-19
sp|Q08632|SDR1_PICAB SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE >g... 94 1e-18
pir||D83416 probable short-chain dehydrogenase PA1828 [imported]... 94 1e-18
sp|P37769|KDUD_ECOLI 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE (2-KETO... 94 2e-18
pir||S02299 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus meg... 93 3e-18
sp|P07999|DHGB_BACME GLUCOSE 1-DEHYDROGENASE B 93 3e-18
pir||D70635 hypothetical protein Rv1928c - Mycobacterium tubercu... 93 3e-18
sp|P39345|IDNO_ECOLI GLUCONATE 5-DEHYDROGENASE (5-KETO-D-GLUCONA... 93 4e-18
pir||S36090 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus sub... 92 5e-18
pir||C70675 hypothetical protein Rv3530c - Mycobacterium tubercu... 92 5e-18
sp|P05406|FIXR_BRAJA FIXR PROTEIN >gi|77956|pir||S01065 probable... 91 1e-17
pir||S74996 enoyl-[acyl-carrier-protein] reductase (NADH) (EC 1.... 91 1e-17
sp|P73016|FABI_SYNY3 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NAD... 91 1e-17
dbj|BAB05561.1| (AP001513) 3-oxoacyl-(acyl-carrier protein) redu... 91 1e-17
emb|CAC17805.1| (AJ292535) SDR-like enzyme [Rhodococcus erythrop... 91 1e-17
pir||H75014 3-oxoacyl-[acyl-carrier-protein] reductase PAB1085 -... 91 1e-17
dbj|BAA94092.1| (AB040809) short chain alcohol dehydrogenase [Ba... 90 2e-17
sp|P73826|FAG2_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 90 2e-17
pir||T36085 probable short chain dehydrogenase - Streptomyces co... 90 2e-17
gi|11498806 2-deoxy-D-gluconate 3-dehydrogenase (kduD) [Archaeog... 90 3e-17
pir||T02175 hypothetical protein F14M4.4 - Arabidopsis thaliana ... 90 3e-17
sp|Q93761|YXEK_CAEEL HYPOTHETICAL OXIDOREDUCTASE F53C11.3 >gi|75... 90 3e-17
gi|10955079 yhg [Agrobacterium tumefaciens] >gi|8572700|gb|AAF77... 90 3e-17
sp|Q05528|KDUD_ERWCH 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE (2-KETO... 89 4e-17
pdb|1HDC|A Chain A, 3-Alpha, 20-Beta-Hydroxysteroid Dehydrogenas... 89 4e-17
pir||B65059 probable dehydrogenase (EC 1.1.1.-) b2774 - Escheric... 89 4e-17
pir||S69225 nogalamycin polyketide ketoreductase (EC 1.1.1.-) sn... 89 4e-17
sp|P76633|YGCW_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN CYSJ-ENO INT... 89 4e-17
gb|AAD32718.1| (AF127374) MitF [Streptomyces lavendulae] 89 4e-17
gb|AAF89839.1|AF173961_5 (AF173961) BbsD [Thauera aromatica] 89 4e-17
gb|AAF75282.1|AF271714_1 (AF271714) beta-hydroxybutyrate dehydro... 89 5e-17
dbj|BAB05863.1| (AP001514) 2,4-dienoyl-CoA reductase (NADPH) [Ba... 89 7e-17
sp|O34717|YKUF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN CHEV-MOBA IN... 88 9e-17
dbj|BAA95121.1| (AB042262) levodione reductase [Corynebacterium ... 88 9e-17
pir||D70707 hypothetical protein Rv0769 - Mycobacterium tubercul... 88 1e-16
gb|AAC95201.1| (AC004561) putative tropinone reductase [Arabidop... 87 2e-16
emb|CAB60183.1| (AL132824) reductase [Streptomyces coelicolor] 87 2e-16
pir||B83332 cis-1,2-dihydroxycyclohexa-3,4-diene carboxylate deh... 87 2e-16
pir||B69802 glucose 1-dehydrogenase homolog yfhR - Bacillus subt... 87 3e-16
gb|AAC69902.1| (AF100956) KE6a [Mus musculus] 87 3e-16
emb|CAC18176.1| (AL451014) probable NADPH-dependent beta-ketoacy... 87 3e-16
gb|AAC44807.1| (U32622) toluenesulfonate zinc-independent alcoho... 86 5e-16
pir||B71923 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1... 86 5e-16
pir||H75330 enoyl-acyl carrier protein reductase - Deinococcus r... 86 5e-16
gb|AAC53573.1| (U34072) steroid dehydrogenase [Mus musculus] 85 6e-16
gb|AAK42451.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 85 8e-16
pir||A64590 probable 3-oxoacyl-[acyl-carrier-protein] reductase ... 85 8e-16
gb|AAF64503.1|AF247810_1 (AF247810) cholesterol oxidase [Nocardi... 85 8e-16
gb|AAC79985.1| (AF053764) NADP-dependent mannitol dehydrogenase ... 85 1e-15
gb|AAF63451.1|AF218267_8 (AF218267) cis-diol dehydrogenase [Pseu... 85 1e-15
gb|AAF45573.1| (AE003419) EG:BACR7A4.14 gene product [Drosophila... 84 1e-15
gi|7305125 H2-K region expressed gene 6 [Mus musculus] >gi|11038... 84 2e-15
pir||T07698 short-chain alcohol dehydrogenase homolog F17N18.70 ... 84 2e-15
gb|AAF05859.1|AC011698_10 (AC011698) putative short-chain type d... 84 2e-15
sp|P15047|ENTA_ECOLI 2,3-DIHYDRO-2,3-DIHYDROXYBENZOATE DEHYDROGE... 83 3e-15
gb|AAB40796.1| (U82598) 2,3-dihydro-2,3-dihydroxybenzoate [Esche... 83 3e-15
emb|CAA07756.1| (AJ007932) ketoreductase [Streptomyces argillaceus] 83 3e-15
gb|AAF60668.1| (AC024791) Hypothetical protein Y47G6A.22 [Caenor... 83 3e-15
emb|CAB61164.1| (AL132973) short chain oxidoreductase [Streptomy... 82 5e-15
gi|6671688 carbonyl reductase 2 [Mus musculus] >gi|113986|sp|P08... 82 9e-15
gb|AAD03695.1| (AF090422) surface sperm protein P26h [Mesocricet... 82 9e-15
gi|7705925 carbonyl reductase [Homo sapiens] >gi|6523809|gb|AAF1... 82 9e-15
pir||T02176 hypothetical protein F14M4.5 - Arabidopsis thaliana ... 81 2e-14
pir||T50271 probable oxidoreductase, short chain dehydrogenase/r... 80 2e-14
emb|CAA07629.1| (AJ007731) 3-ketoacyl-ACP/CoA redutase [Streptom... 80 4e-14
dbj|BAB04426.1| (AP001509) D-mannonate oxidoreductase [Bacillus ... 80 4e-14
emb|CAC01650.1| (AL391072) putative oxidoreductase [Streptomyces... 79 5e-14
dbj|BAB04225.1| (AP001508) dehydrogenase/reductase [Bacillus hal... 79 5e-14
emb|CAB77292.1| (AL160312) putative 3-oxoacyl-[acyl-carrier prot... 79 6e-14
emb|CAC14380.1| (AL445963) putative oxidoreductase [Streptomyces... 78 8e-14
emb|CAB69778.1| (AL137187) putative dehydrogenase [Streptomyces ... 78 1e-13
sp|P23102|XYLL_PSEPU CIS-1,2-DIHYDROXYCYCLOHEXA-3,5-DIENE-1-CARB... 77 2e-13
sp|P22441|DHMA_FLAS1 N-ACYLMANNOSAMINE 1-DEHYDROGENASE (NAM-DH) ... 77 2e-13
pir||S23485 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehyd... 77 2e-13
gb|AAF05840.1|AF197058_1 (AF197058) trans-2-enoyl-ACP reductase ... 77 2e-13
emb|CAA74944.1| (Y14603) sorbitol-6-phosphate dehydrogenase [Erw... 76 3e-13
sp|Q22230|YVX3_CAEEL HYPOTHETICAL OXIDOREDUCTASE T05C12.3 >gi|75... 76 3e-13
pir||S07135 ribitol 2-dehydrogenase (EC 1.1.1.56) - Klebsiella p... 76 4e-13
sp|P55541|Y4LA_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYDROGENASE/RED... 76 4e-13
emb|CAC11881.1| (AL445065) glucose 1-dehydrogenase related prote... 75 9e-13
pir||T06212 glucose and ribitol dehydrogenase homolog - barley >... 75 1e-12
emb|CAB91875.1| (AJ277945) putative alcohol dehydrogenase [Lycop... 75 1e-12
dbj|BAB01821.1| (AB026657) alcohol dehydrogenase-like protein [A... 75 1e-12
pir||S07134 ribitol 2-dehydrogenase (EC 1.1.1.56) - Klebsiella p... 74 2e-12
pir||B70640 hypothetical protein Rv0687 - Mycobacterium tubercul... 74 2e-12
sp|Q29529|CBR2_PIG LUNG CARBONYL REDUCTASE [NADPH] (NADPH-DEPEND... 74 2e-12
emb|CAC11623.1| (AL445064) conserved hypothetical protein [Therm... 74 2e-12
sp|P00335|RIDH_KLEAE RIBITOL 2-DEHYDROGENASE (RDH) 73 3e-12
pir||S75500 short-chain alcohol dehydrogenase-related protein, 2... 73 3e-12
pir||T51721 sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) ... 73 3e-12
emb|CAC18242.1| (AL451018) related to SORBITOL UTILIZATION PROTE... 73 3e-12
gb|AAC98135.1| (AF098273) D-mannonate oxidoreductase [Bacillus s... 73 5e-12
pir||H83046 probable short-chain dehydrogenase PA4786 [imported]... 73 5e-12
sp|Q05069|FABI_ANASP ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NAD... 72 6e-12
pir||C83133 probable short-chain dehydrogenase PA4098 [imported]... 72 6e-12
pir||DEKBR ribitol 2-dehydrogenase (EC 1.1.1.56) - Enterobacter ... 72 6e-12
gb|AAD04184.1| (L10036) unknown [Anabaena PCC7120] 72 6e-12
sp|O00058|PIG8_UROFA SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE HO... 72 6e-12
gb|AAF24130.1|AF129168_3 (AF129168) D-sorbitol-6-phosphate dehyd... 72 8e-12
gb|AAB42054.1| (U53828) STA1-12 [Silene latifolia subsp. alba] 71 1e-11
emb|CAB59666.1| (AL132674) probable oxidoreductase [Streptomyces... 71 1e-11
prf||741688A dehydrogenase,ribitol [Klebsiella aerogenes] 71 2e-11
pir||A70637 hypothetical protein Rv1941 - Mycobacterium tubercul... 70 2e-11
dbj|BAB04519.1| (AP001509) dehydrogenase/reductase family [Bacil... 70 2e-11
pir||T38157 oxidoreducatase, possible sorbitol utilizationshort ... 70 3e-11
emb|CAB94622.1| (AL359214) putative oxidoreductase [Streptomyces... 69 4e-11
gb|AAF89838.1|AF173961_4 (AF173961) BbsC [Thauera aromatica] 69 4e-11
gb|AAD13552.1| (AF080235) reductase homolog [Streptomyces cyanog... 69 5e-11
gb|AAG13989.1|AF006680_1 (AF006680) isoepoxydon dehydrogenase [P... 69 5e-11
gb|AAG20666.1| (AE005135) oxidoreductase; YusZ2 [Halobacterium s... 69 5e-11
sp|Q56632|VIBA_VIBCH VIBRIOBACTIN-SPECIFIC 2,3-DIHYDRO-2,3-DIHYD... 69 7e-11
pir||T11579 probable short chain alcohol dehydrogenase CPRD12, d... 68 9e-11
>pir||C75217 probable short-chain dehydrogenase/reductase PAB2177 - Pyrococcus
abyssi (strain Orsay) >gi|5457695|emb|CAB49186.1|
(AJ248283) PUTATIVE SHORT-CHAIN DEHYDROGENASE/REDUCTASE
[Pyrococcus abyssi]
Length = 263
Score = 516 bits (1314), Expect = e-145
Identities = 263/263 (100%), Positives = 263/263 (100%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV
Sbjct: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
Query: 61 HYIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
HYIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA
Sbjct: 61 HYIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI
Sbjct: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA
Sbjct: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
Query: 241 SDLGSYINGAMIPVDGGRLNSVF 263
SDLGSYINGAMIPVDGGRLNSVF
Sbjct: 241 SDLGSYINGAMIPVDGGRLNSVF 263
>pir||C71204 probable dehydrogenase - Pyrococcus horikoshii
>gi|3258343|dbj|BAA31026.1| (AP000007) 282aa long
hypothetical dehydrogenase [Pyrococcus horikoshii]
Length = 282
Score = 494 bits (1258), Expect = e-139
Identities = 247/263 (93%), Positives = 260/263 (97%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
ML+IDLSGKLAFTTASSKGIGFGVARVLA+AGADVIILSRNEENLKRA+EKIK ESNVEV
Sbjct: 20 MLRIDLSGKLAFTTASSKGIGFGVARVLARAGADVIILSRNEENLKRAKEKIKSESNVEV 79
Query: 61 HYIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
HYIVADLTKM+DLERT+KELK+IG+PDIFFFSTGGPKPGYFMEMSMEDWE AVKLLLYPA
Sbjct: 80 HYIVADLTKMEDLERTIKELKDIGDPDIFFFSTGGPKPGYFMEMSMEDWEGAVKLLLYPA 139
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+YLTKALVP MERKGFGRI+YSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI
Sbjct: 140 VYLTKALVPGMERKGFGRIVYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 199
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVNGIMPGIIRTDR+IQLAQDRAKREGK+VEEAL+EYAKPIPLGRLGEPEEIGYLVAFLA
Sbjct: 200 TVNGIMPGIIRTDRVIQLAQDRAKREGKSVEEALKEYAKPIPLGRLGEPEEIGYLVAFLA 259
Query: 241 SDLGSYINGAMIPVDGGRLNSVF 263
S+LGSYINGAMIPVDGGRLNSVF
Sbjct: 260 SELGSYINGAMIPVDGGRLNSVF 282
>pir||H72686 probable dehydrogenase APE0912 - Aeropyrum pernix (strain K1)
>gi|5104581|dbj|BAA79896.1| (AP000060) 260aa long
hypothetical dehydrogenase [Aeropyrum pernix]
Length = 260
Score = 240 bits (605), Expect = 2e-62
Identities = 116/257 (45%), Positives = 176/257 (68%), Gaps = 1/257 (0%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKE-ESNVEV 60
+ + + GKLA TA S G+GF A LA+ GA +++ SRN E L+ A +I S +V
Sbjct: 1 MDLGIQGKLAVVTAGSSGLGFASALELARNGARLLLFSRNREKLEAAASRIASLVSGAQV 60
Query: 61 HYIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ D+ + D++R ++ +++G DI +STGGP+PG FME+ +EDW+E+ +LL A
Sbjct: 61 DIVAGDIREPGDIDRLFEKARDLGGADILVYSTGGPRPGRFMELGVEDWDESYRLLARSA 120
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+++ + M KG+GR++Y SV + P ++ALSN++R+ + G+VRTLA EL P G+
Sbjct: 121 VWVGRRAAEQMVEKGWGRMVYIGSVTLLRPWQDLALSNIMRLPVIGVVRTLALELAPHGV 180
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN ++P +I TDR+ LA++RA+R G TVEEAL+ A IP+GR+G+PEE+ +VAFLA
Sbjct: 181 TVNAVLPSLILTDRVRSLAEERARRSGITVEEALKSMASRIPMGRVGKPEELASVVAFLA 240
Query: 241 SDLGSYINGAMIPVDGG 257
S+ S+I GA+IPVDGG
Sbjct: 241 SEKASFITGAVIPVDGG 257
>gb|AAK42438.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-5) [Sulfolobus
solfataricus]
Length = 261
Score = 233 bits (587), Expect = 2e-60
Identities = 119/263 (45%), Positives = 171/263 (64%), Gaps = 3/263 (1%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ + + GK TA+SKGIG +A+ + GA VII S +E NL +A K+KE + V
Sbjct: 1 MDLGIKGKKVIVTAASKGIGLAIAKRFLEEGAKVIISSNDESNLMKAYNKLKEIHSENVS 60
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
YI ADL +++ V E + +G D+ + TG PKPG +S +DW +A LLL A
Sbjct: 61 YIKADLMNPHEVKSLVHEGYRKLGGLDVLAYVTGSPKPGNLFSLSDKDWMDAFNLLLLSA 120
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+ + M+ G RII STS +++PI N+ LSNVVR+++AGL++ ++ELGPKGI
Sbjct: 121 VVAVREAGQLMQSGG--RIILSTSTTLRQPIDNLDLSNVVRLSLAGLIKVASRELGPKGI 178
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VNG+MPG +T+R++Q+ +DRA REGK+ +E L+ +PLGR GEPEEI +V FLA
Sbjct: 179 LVNGVMPGWTKTERLLQIIRDRAIREGKSEDEVLKSIVADVPLGRAGEPEEIANVVLFLA 238
Query: 241 SDLGSYINGAMIPVDGGRLNSVF 263
S+L +Y+ GA+IPVDGG + VF
Sbjct: 239 SNLSTYVTGALIPVDGGSIKGVF 261
>pir||D72285 3-oxoacyl-(acyl carrier protein) reductase - Thermotoga maritima
(strain MSB8) >gi|4981718|gb|AAD36244.1|AE001774_1
(AE001774) 3-oxoacyl-(acyl carrier protein) reductase
[Thermotoga maritima]
Length = 237
Score = 168 bits (422), Expect = 5e-41
Identities = 97/256 (37%), Positives = 152/256 (58%), Gaps = 25/256 (9%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+++ + K A+S+GIG VA VL++ GA+V I +RNEE LKR+ +
Sbjct: 1 MELGIRDKGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSGHR---------- 50
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
Y+V DL K DL+ +++K + DI + GGPK G+F E++ ED++EA+ L I
Sbjct: 51 YVVCDLRK--DLDLLFEKVKEV---DILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMI 105
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
+ + +PAM+ KG+GRI+ TS ++ PI N+ SN R+A+ G ++TL+ E+ P GIT
Sbjct: 106 KIVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGIT 165
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG T+R+ +L + K++ ++ IP+ R+ +PEEI +VAFL S
Sbjct: 166 VNCVAPGWTETERVKELLSEEKKKQVES----------QIPMRRMAKPEEIASVVAFLCS 215
Query: 242 DLGSYINGAMIPVDGG 257
+ SY+ G I VDGG
Sbjct: 216 EKASYLTGQTIVVDGG 231
>gb|AAG20295.1| (AE005104) putative oxidoreductase; OxrA [Halobacterium sp. NRC-1]
Length = 261
Score = 160 bits (401), Expect = 1e-38
Identities = 95/260 (36%), Positives = 144/260 (54%), Gaps = 3/260 (1%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+++ L G +A TASS G+G A LA+ GADV++ SR+EE + A E+I ++ V
Sbjct: 1 MELGLDGDVAVVTASSSGLGKASAAALAREGADVVVCSRDEERVVAAAEEIGADAAGSVR 60
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ AD+T D+ V+ ++ G D S GG G F ++ +DW +A +LL+
Sbjct: 61 GVPADITDGADVAAVVETAVETFGGLDHVVTSAGGVPSGQFTAVTDDDWTDAFELLVMSV 120
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+ A + G + TS ++ EPI + LSN VR + GL +T+A+E P +
Sbjct: 121 VRTLDAAHEHLVAGDGGTVTCITSTSVSEPIEGLVLSNAVRRGVVGLAKTVAREWAPD-V 179
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKR-EGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
N + PG T R+ +L R E + E L +++ +PL RLGEP E+G +VAFL
Sbjct: 180 RANVVQPGPHETARIEELVSAAVARGEADSYEAGLAGWSEEVPLDRLGEPSELGDVVAFL 239
Query: 240 ASDLGSYINGAMIPVDGGRL 259
ASD S++ GA +PVDGGRL
Sbjct: 240 ASDRASFVTGASVPVDGGRL 259
>emb|CAC11951.1| (AL445065) 3-oxoacyl-[acyl-carrier-protein] reductase related
protein [Thermoplasma acidophilum]
Length = 269
Score = 160 bits (400), Expect = 2e-38
Identities = 86/255 (33%), Positives = 150/255 (58%), Gaps = 6/255 (2%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ +S A +A+S GIG G+A VL+++G + + +R+E+ + AR+++K + +E I
Sbjct: 14 VSISMPNAIVSAASSGIGKGIASVLSRSGYRLTLFARDEKRIDEARKELKLKFGLEPLAI 73
Query: 64 VADLTKMDDLERTVKELKNI-GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
ADL+K +D++R VK+ + G + + G P+ F ++S EDW+ A+ ++ +
Sbjct: 74 PADLSKPEDIDRVVKKHRETYGSIENLVINYGDPRVAGFTDLSDEDWQYAIDMIFMSTVR 133
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+T+ + M R G I+Y TS+ ++EP+ +LS+ +R A+ L + ++ E+ GI +
Sbjct: 134 ITREALKDMIRARHGSIVYVTSMTVREPMEGFSLSSSLRSAVVALAKNISLEVSKFGIRI 193
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I G I T+R+ + + R E ++ + +PL R+G+PEEIG +V FL S
Sbjct: 194 NTISQGYINTERLRDVIKTGVDR-----TEGMRRLSGDVPLRRVGDPEEIGEVVEFLLSS 248
Query: 243 LGSYINGAMIPVDGG 257
SY+NGA IPVDGG
Sbjct: 249 RASYVNGANIPVDGG 263
>gb|AAK41248.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-1) [Sulfolobus
solfataricus]
Length = 265
Score = 152 bits (379), Expect = 5e-36
Identities = 94/266 (35%), Positives = 150/266 (56%), Gaps = 6/266 (2%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ I++SGK TAS++GIG G+A + G +V+I SRN++ +++A ++++ V
Sbjct: 1 MNINISGKRVLVTASTEGIGRGIAEAFLREGCNVVISSRNKDKIEKAILEMRK-IGPSVW 59
Query: 62 YIVADLTKMDDLERTVK-ELKNIGEPDIFFFSTGGP--KPGYFMEMSMEDWEEAVKLLLY 118
ADLT LE V LK + DI ++G P +P YF E +MEDWE A KL L
Sbjct: 60 GFPADLTDFKSLEELVGYALKIMNGIDILVVNSGNPPKEPSYFFENTMEDWEYATKLYLL 119
Query: 119 PAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
AI LT + M+ + +GRI + +S IKEP +L+++ R + + + L+KELG
Sbjct: 120 SAIKLTNLVYQYMKAQRWGRIFFLSSWTIKEPQRIFSLADITRAPLIQMAKLLSKELGEY 179
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEA-LQEYAKPIPLGRLGE-PEEIGYLV 236
+ VN I+ G T+ + + A++ G+ ++ +E IP+GR G+ E+G L+
Sbjct: 180 NVNVNVILMGSFETEGAKRSLKKYAEKVGQPLDVIWKREVISQIPIGRTGDIKNELGSLL 239
Query: 237 AFLASDLGSYINGAMIPVDGGRLNSV 262
FL+SD YING I +DGG ++
Sbjct: 240 VFLSSDYAGYINGTSILIDGGMSRAI 265
>sp|O67610|FABG_AQUAE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7430985|pir||H70447
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) - Aquifex aeolicus >gi|2984032|gb|AAC07575.1|
(AE000752) 3-oxoacyl-[acyl-carrier-protein] reductase
[Aquifex aeolicus]
Length = 248
Score = 146 bits (364), Expect = 3e-34
Identities = 86/257 (33%), Positives = 137/257 (52%), Gaps = 12/257 (4%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
++I L GK++ T S++GIG +A LA AG+ VII + E K E+I + V+ H
Sbjct: 1 MEIKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAH 60
Query: 62 YIVADLTKMDDLERTVKELKNIGEP-DIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ +L + + + +E+ N+ + DI + G + F+ MS+ DWEE +K+ L
Sbjct: 61 GVEMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGT 120
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+T+ + M ++ +GRI+ +SV + + + G ++LAKEL P+ +
Sbjct: 121 FLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNV 180
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN + PG I TD L+ EE Q+Y + IPLGR G PEE+ +V FL
Sbjct: 181 LVNAVAPGFIETDMTAVLS-----------EEIKQKYKEQIPLGRFGSPEEVANVVLFLC 229
Query: 241 SDLGSYINGAMIPVDGG 257
S+L SYI G +I V+GG
Sbjct: 230 SELASYITGEVIHVNGG 246
>dbj|BAB18775.1| (AB045131) NADPH-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 260
Score = 144 bits (360), Expect = 9e-34
Identities = 92/254 (36%), Positives = 145/254 (56%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ K+A TAS+ GIGF +AR LA+ GA V++ SR ++N+ +A ++ E + V V
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG-LSVTGTVC 70
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D ER V +K G DI + P G M+++ E W++ + + + +
Sbjct: 71 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 130
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TKA+VP ME++G G ++ +S+A P P + NV + A+ GL +TLA EL P+ I VN
Sbjct: 131 TKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVN 190
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG+I+T L D+ K EE+++E + + RLGEPE+ +V+FL S+
Sbjct: 191 CLAPGLIKTSFSRMLWMDKEK------EESMKE---TLRIRRLGEPEDCAGIVSFLCSED 241
Query: 244 GSYINGAMIPVDGG 257
SYI G + V GG
Sbjct: 242 ASYITGETVVVGGG 255
>gi|10337605 peroxisomal short-chain alcohol dehydrogenase [Homo sapiens]
>gi|4105190|gb|AAD02292.1| (AF044127) peroxisomal
short-chain alcohol dehydrogenase [Homo sapiens]
Length = 260
Score = 144 bits (360), Expect = 9e-34
Identities = 92/254 (36%), Positives = 145/254 (56%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ K+A TAS+ GIGF +AR LA+ GA V++ SR ++N+ +A ++ E + V V
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG-LSVTGTVC 70
Query: 66 DLTKMDDLERTVK-ELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D ER V +K G DI + P G M+++ E W++ + + + +
Sbjct: 71 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALM 130
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TKA+VP ME++G G ++ +S+A P P + NV + A+ GL +TLA EL P+ I VN
Sbjct: 131 TKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVN 190
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG+I+T L D+ K EE+++E + + RLGEPE+ +V+FL S+
Sbjct: 191 CLAPGLIKTSFSRMLWMDKEK------EESMKE---TLRIRRLGEPEDCAGIVSFLCSED 241
Query: 244 GSYINGAMIPVDGG 257
SYI G + V GG
Sbjct: 242 ASYITGETVVVGGG 255
>dbj|BAA91953.1| (AK001870) unnamed protein product [Homo sapiens]
Length = 278
Score = 144 bits (360), Expect = 9e-34
Identities = 92/254 (36%), Positives = 145/254 (56%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ K+A TAS+ GIGF +AR LA+ GA V++ SR ++N+ +A ++ E + V V
Sbjct: 30 LANKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG-LSVTGTVC 88
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D ER V +K G DI + P G M+++ E W++ + + + +
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TKA+VP ME++G G ++ +S+A P P + NV + A+ GL +TLA EL P+ I VN
Sbjct: 149 TKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVN 208
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG+I+T L D+ K EE+++E + + RLGEPE+ +V+FL S+
Sbjct: 209 CLAPGLIKTSFSRMLWMDKEK------EESMKE---TLRIRRLGEPEDCAGIVSFLCSED 259
Query: 244 GSYINGAMIPVDGG 257
SYI G + V GG
Sbjct: 260 ASYITGETVVVGGG 273
>gi|11433956 peroxisomal short-chain alcohol dehydrogenase [Homo sapiens]
Length = 278
Score = 141 bits (352), Expect = 8e-33
Identities = 91/254 (35%), Positives = 144/254 (55%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ K+A TAS+ GIGF +AR LA+ A V++ SR ++N+ +A ++ E + V V
Sbjct: 30 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEG-LSVTGTVC 88
Query: 66 DLTKMDDLERTVK-ELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D ER V +K G DI + P G M+++ E W++ + + + +
Sbjct: 89 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALM 148
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TKA+VP ME++G G ++ +S+A P P + NV + A+ GL +TLA EL P+ I VN
Sbjct: 149 TKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVN 208
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG+I+T L D+ K EE+++E + + RLGEPE+ +V+FL S+
Sbjct: 209 CLAPGLIKTSFSRMLWMDKEK------EESMKE---TLRIRRLGEPEDCAGIVSFLCSED 259
Query: 244 GSYINGAMIPVDGG 257
SYI G + V GG
Sbjct: 260 ASYITGETVVVGGG 273
>pir||D75472 oxidoreductase, short-chain dehydrogenase/reductase family -
Deinococcus radiodurans (strain R1)
>gi|6458534|gb|AAF10397.1|AE001936_6 (AE001936)
oxidoreductase, short-chain dehydrogenase/reductase
family [Deinococcus radiodurans]
Length = 266
Score = 141 bits (351), Expect = 1e-32
Identities = 84/252 (33%), Positives = 131/252 (51%), Gaps = 18/252 (7%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK A T SKGIG AR L + GA+V + +R EE L+RA E ++ ++VA
Sbjct: 30 LDGKRALVTGGSKGIGLAAARQLRELGAEVTLAARGEETLRRAAE------DIGAAWVVA 83
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
D++ + ++ G+ DI + GGP P E++ WE+ + L
Sbjct: 84 DVSTPEGVKVAADAA---GQVDILVSNAGGPPPSLPSEVTEAAWEQGFQTTFLSTARLVD 140
Query: 126 ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
A++P M + +GRII TS+ + P + +SN +R A+ +RTLA E+ G+T N +
Sbjct: 141 AVLPGMRERRWGRIIAITSLTVGRPSLTLPVSNALRAAVTNHLRTLALEVAADGVTCNTV 200
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG T+R+ +L D A+ + + IP R GEP+E+ +AFLA++ +
Sbjct: 201 APGYTATERLQKLHADPAEAD---------KLRAKIPARRFGEPDEVASAIAFLATNEAA 251
Query: 246 YINGAMIPVDGG 257
YI G + VDGG
Sbjct: 252 YITGQELLVDGG 263
>dbj|BAB18776.1| (AB045132) NADPH-dependent retinol dehydrogenase/reductase [Mus
musculus]
Length = 260
Score = 139 bits (348), Expect = 2e-32
Identities = 90/254 (35%), Positives = 144/254 (56%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
LS K+A TAS+ GIGF +AR LA+ GA V++ SR ++N+ RA ++ E + V IV
Sbjct: 12 LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEG-LSVTGIVC 70
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D E+ + LK DI + P G M+++ E W++ + + + +
Sbjct: 71 HVGKAEDREKLITTALKRHQGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMM 130
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
KA+VP ME++G G ++ SVA P++ NV + A+ GL + A EL PK I VN
Sbjct: 131 IKAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVN 190
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG+I+T L +++A+ + ++EA+Q + RLG+PE+ +V+FL S+
Sbjct: 191 CLAPGLIKTRFSSVLWEEKARED--FIKEAMQ-------IRRLGKPEDCAGIVSFLCSED 241
Query: 244 GSYINGAMIPVDGG 257
SYING + V GG
Sbjct: 242 ASYINGETVVVGGG 255
>pir||T22676 hypothetical protein F54F3.4 - Caenorhabditis elegans
>gi|3877595|emb|CAB01974.1| (Z79696) predicted using
Genefinder~Similarity to Human HEP27 protein
(TR:G1079566), contains similarity to Pfam domain:
PF00106 (short chain dehydrogenase), Score=187.6,
E-value=6.3e-53, N=1; PF00678 (Short chain
dehydrogenase/reductase C-terminus), S>
>gi|3879853|emb|CAB04734.1| (Z81592) predicted using
Genefinder~Similarity to Human HEP27 protein
(TR:G1079566), contains similarity to Pfam domain:
PF00106 (short chain dehydrogenase), Score=187.6,
E-value=6.3e-53, N=1; PF00678 (Short chain
dehydrogenase/reductase C-terminus), S>
Length = 260
Score = 139 bits (347), Expect = 3e-32
Identities = 90/252 (35%), Positives = 140/252 (54%), Gaps = 8/252 (3%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GK+A TA++KGIG +A L GA V+I SRN++N+ A E +K + +V I +
Sbjct: 10 GKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHI 69
Query: 68 TKMDDLERTVK-ELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
DD ++ V L+ G+ +I + G P G+ +E+S + W++ ++ + +TK
Sbjct: 70 ASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTK 129
Query: 126 ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
+ P + ++G G II++ S + + P IA V + + GL R LA L I VNGI
Sbjct: 130 LVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGI 189
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG+I+T +M Q+ D G+ E+ L + + I LGRLG P++ VA+LASD S
Sbjct: 190 APGVIKT-KMSQVLWD----GGEDAEKELTD-IQEIALGRLGVPDDCAGTVAYLASDDSS 243
Query: 246 YINGAMIPVDGG 257
YI G MI + GG
Sbjct: 244 YITGEMIIIAGG 255
>dbj|BAB18777.1| (AB045133) NADPH-dependent retinol dehydrogenase/reductase
[Oryctolagus cuniculus]
Length = 260
Score = 137 bits (342), Expect = 1e-31
Identities = 88/254 (34%), Positives = 138/254 (53%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ K+A TAS+ GIG +AR LA+ GA V+I SR ++N+ RA ++ E + V V
Sbjct: 12 LANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEG-LSVTGTVC 70
Query: 66 DLTKMDDLERTVKELKNI-GEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D ER V N+ G DI + P G M+++ E W++ + + + +
Sbjct: 71 HVGKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALM 130
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TKA+VP ME++G G ++ S+A P + NV + A+ GL + LA EL + I VN
Sbjct: 131 TKAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVN 190
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG+I+T L +D+A+ E + + + RLG+PEE +V+FL S+
Sbjct: 191 CLAPGLIKTSFSKALWEDKAQEE---------NIIQKLRIRRLGKPEECAGIVSFLCSED 241
Query: 244 GSYINGAMIPVDGG 257
SYI G + V GG
Sbjct: 242 ASYITGETVVVAGG 255
>dbj|BAB06210.1| (AP001515) 3-oxoacyl-(acyl-carrier protein) reductase [Bacillus
halodurans]
Length = 246
Score = 137 bits (342), Expect = 1e-31
Identities = 95/257 (36%), Positives = 137/257 (52%), Gaps = 20/257 (7%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVHYIV 64
L GK A T +S+GIG A LA+ GA+V++ + N+E ++ +IKE VE I
Sbjct: 2 LQGKTAIVTGASRGIGRATAMELARHGANVVVNYAGNKEKAEKVVAEIKE-LGVEAIAIQ 60
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
AD+ + ++ VKE + G DI + G + FM M EDW+ + L +
Sbjct: 61 ADVADSESVQAMVKETIDTFGAVDILVNNAGITRDNLFMRMKEEDWDAVIDTNLKGVFHC 120
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVV--RIAMAGLVRTLAKELGPKGIT 181
+KA+ M ++ FGRII +SV I N +N V + + GL +TLA+EL + IT
Sbjct: 121 SKAVTRPMMKQRFGRIINVSSVV--GAIGNAGQANYVAAKAGVIGLTKTLARELANRNIT 178
Query: 182 VNGIMPGIIRTDRMIQLAQD-RAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN + PG I TD +L +D +A+ G+ IPL RLG+PEE+ V FLA
Sbjct: 179 VNAVAPGFIETDMTGELPEDVKAQMLGQ------------IPLARLGQPEEVAKAVRFLA 226
Query: 241 SDLGSYINGAMIPVDGG 257
SD SY+ G I V+GG
Sbjct: 227 SDDASYLTGQTIHVNGG 243
>emb|CAB59447.1| (AL132644) putative oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 251
Score = 137 bits (341), Expect = 2e-31
Identities = 89/256 (34%), Positives = 135/256 (51%), Gaps = 10/256 (3%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ + L ++ T +++G+G AR L GA V++ R+E+++ +A + ++ V V
Sbjct: 1 MDLGLKDRVYVVTGATRGLGNAAARELVADGAKVVVTGRDEKSVAQAAAALGPDA-VGVA 59
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
AD L T +E G D S GGP PG+ + + E W+ A + + A+
Sbjct: 60 ADNADPEAAGRLIATARE--RFGRFDGVLISVGGPPPGFVADTTDEQWQSAFESVFLGAV 117
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
L +A A E G I + S ++ EPIP + +SN +R +AG ++LA ELGP+GI
Sbjct: 118 RLARAA--AAELADGGVIGFVLSGSVHEPIPGLTISNGLRPGLAGFAKSLADELGPRGIR 175
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
V G++PG + TDR+ +L D + + A + IPL R G PEE G AFL S
Sbjct: 176 VVGLLPGRVDTDRVREL--DGLSADPEATRAAAE---SRIPLRRYGAPEEFGRASAFLLS 230
Query: 242 DLGSYINGAMIPVDGG 257
SYI G M+PVDGG
Sbjct: 231 PAASYITGVMLPVDGG 246
>pir||T32002 hypothetical protein F36H9.3 - Caenorhabditis elegans
>gi|2315645|gb|AAB66092.1| (AF016668) strong similarity
to the insect-type alcohol dehydrogenase family
[Caenorhabditis elegans]
Length = 257
Score = 136 bits (338), Expect = 3e-31
Identities = 85/254 (33%), Positives = 135/254 (52%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ ++A TAS+KGIGF +A+ L AGA V++ SR +EN+ A ++ E N++ H A
Sbjct: 9 LTDRVALVTASTKGIGFAIAKQLGAAGASVVVCSRKKENVDEAVAALRLE-NIDAHGTTA 67
Query: 66 DLTKMDDLERTVK-ELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ D + + L + DI + P G M+++ W++ + L + A L
Sbjct: 68 HVGNKSDRTKLIDFTLDRFTKLDILVSNAAVNPHYGDLMKVTDSQWDKLLDLNVKSAFEL 127
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TK VP +E G G +++ +SVA P+ I +V++ + GL ++LA L + I VN
Sbjct: 128 TKEAVPHLEASGRGNVVFVSSVAGYSPMNEIGAYSVMKTTLTGLSKSLALNLARRNIRVN 187
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
I PGII+TD L D +++ Q++ I R G+P+E VAFL SD
Sbjct: 188 SIAPGIIQTDFSQVLFSDESEK---------QKWLSQIAQRRFGDPDECAEAVAFLVSDE 238
Query: 244 GSYINGAMIPVDGG 257
SYI+G I ++GG
Sbjct: 239 ASYISGETIGINGG 252
>gb|AAK43217.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-10) [Sulfolobus
solfataricus]
Length = 252
Score = 134 bits (335), Expect = 8e-31
Identities = 88/258 (34%), Positives = 135/258 (52%), Gaps = 19/258 (7%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV---H 61
DLSG++A T + GIG +A LA GA V++ E LK +I ++++ +V +
Sbjct: 6 DLSGRIAIVTGGASGIGRAIAFKLASLGATVVLGDVKLEELKNVVNEITQQTSSKVLPLY 65
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
V D + + E+ I DI + G + F++M+ E W+E +K+ LY
Sbjct: 66 VNVGDFNSAKEFYQKATEILGIDYVDILVNNAGINRDALFVKMTFEQWDEVMKVDLYSMF 125
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKG 179
+TK +V M R+ +GRII +S++ + NI +N + + G +TLA+EL
Sbjct: 126 NMTKQVVDGMIRRNYGRIINMSSMSW---LGNIGQANYSAAKAGVIGFTKTLARELAKYN 182
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
ITVN I PG I T RA E+ Q+ + IP+GR+G PEE+ L+AFL
Sbjct: 183 ITVNAITPGFIDTP------MTRA-----VPEKVRQKIIERIPMGRVGSPEEVANLIAFL 231
Query: 240 ASDLGSYINGAMIPVDGG 257
+S+ SYI G +I V GG
Sbjct: 232 SSEEASYITGEVIGVTGG 249
>sp|Q13268|HE27_HUMAN HEP27 PROTEIN (PROTEIN D)
Length = 258
Score = 130 bits (324), Expect = 2e-29
Identities = 89/253 (35%), Positives = 136/253 (53%), Gaps = 13/253 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ ++A T S+ GIGF +AR LA+ GA V+I SR ++N+ RA K++ E + V IV
Sbjct: 12 LANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG-LSVAGIVC 70
Query: 66 DLTKMDDLERTV-KELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D E+ V K L++ G D S G P G + S + W++ + + + L
Sbjct: 71 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALL 130
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
L+P ME + G +I +S+A P+ + + NV + A+ GL RTLA EL PK I VN
Sbjct: 131 LSQLLPYMENRR-GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVN 189
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
++PGII+TD + E + + + L R+GE E+ +V+FL S
Sbjct: 190 CVVPGIIKTD---------FSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPD 240
Query: 244 GSYINGAMIPVDG 256
SY+NG I V G
Sbjct: 241 ASYVNGENIAVAG 253
>gi|5031737 short-chain alcohol dehydrogenase family member [Homo sapiens]
>gi|11433950|ref|XP_007293.1| short-chain alcohol
dehydrogenase family member [Homo sapiens]
>gi|2135333|pir||S66665 nuclear protein Hep27 - human
>gi|1079566|gb|AAA82048.1| (U31875) Hep27 protein [Homo
sapiens] >gi|11275675|gb|AAG33703.1| (AF244132)
short-chain alcohol dehydrogenase [Homo sapiens]
Length = 280
Score = 130 bits (324), Expect = 2e-29
Identities = 89/253 (35%), Positives = 136/253 (53%), Gaps = 13/253 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ ++A T S+ GIGF +AR LA+ GA V+I SR ++N+ RA K++ E + V IV
Sbjct: 34 LANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG-LSVAGIVC 92
Query: 66 DLTKMDDLERTV-KELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ K +D E+ V K L++ G D S G P G + S + W++ + + + L
Sbjct: 93 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALL 152
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
L+P ME + G +I +S+A P+ + + NV + A+ GL RTLA EL PK I VN
Sbjct: 153 LSQLLPYMENRR-GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVN 211
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
++PGII+TD + E + + + L R+GE E+ +V+FL S
Sbjct: 212 CVVPGIIKTD---------FSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPD 262
Query: 244 GSYINGAMIPVDG 256
SY+NG I V G
Sbjct: 263 ASYVNGENIAVAG 275
>emb|CAB58301.1| (AL121854) putative oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 257
Score = 129 bits (320), Expect = 5e-29
Identities = 86/265 (32%), Positives = 133/265 (49%), Gaps = 19/265 (7%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL ++A SKG G AR+L +AGA V+ ++R + +V ++
Sbjct: 5 DLDERVAVVAGGSKGAGLATARLLREAGARVVSIARTAP------------ATADVVFVP 52
Query: 65 ADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKP--GYFMEMSMEDWEEAVKLLLYPAI 121
A L+ + ++ + + + +G PDI GG + G + + E W + + L L PA+
Sbjct: 53 AGLSTPEGVKASSEAVAELVGVPDILVHVVGGSRSPAGGYAALDDERWAQELSLNLLPAV 112
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVV-RIAMAGLVRTLAKELGPKGI 180
L +A+VP M +G G I++ TS+ + P+ + L+ + A+ + LA E+ P G+
Sbjct: 113 RLDRAIVPGMVARGSGAIVHVTSIQRRMPLHDSTLAYAAAKSALTTYSKGLANEVAPAGV 172
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKP---IPLGRLGEPEEIGYLVA 237
VN + PG IRTD L R T E AL E + IPLGR EPEE+ +A
Sbjct: 173 RVNSVAPGFIRTDGAEALLARRMSESRITREAALGELMRVLGGIPLGRPAEPEEVAETIA 232
Query: 238 FLASDLGSYINGAMIPVDGGRLNSV 262
FL SD S I G+ VDGG + +V
Sbjct: 233 FLVSDRASGITGSEHVVDGGTIRTV 257
>pir||E81695 3-oxoacyl-(acyl carrier protein) reductase TC0508 [imported] -
Chlamydia muridarum (strain Nigg)
>gi|7190547|gb|AAF39350.1| (AE002319) 3-oxoacyl-(acyl
carrier protein) reductase [Chlamydia muridarum]
Length = 248
Score = 128 bits (318), Expect = 8e-29
Identities = 84/253 (33%), Positives = 125/253 (49%), Gaps = 12/253 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L K A T S+GIGFG+A++ A+ GA+V I NEE K A + + +++ +V + +
Sbjct: 5 LVNKAAIVTGGSRGIGFGIAKLFAEHGANVQIWGINEEAGKSAAQDLSDKTGSKVSFALV 64
Query: 66 DLTKMDDLERTV-KELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D++K D + V K L G D+ + G + M MS E+W + L +
Sbjct: 65 DVSKNDMVSAQVQKFLAEYGTIDVVVNNAGITRDSLLMRMSEEEWSSVIDTNLGSIYNVC 124
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
A++ M + G I+ +S+ P + + G + L+KE+G K I VN
Sbjct: 125 SAVIRPMIKARSGAIVNISSIVGLRGSPGQTNYAAAKAGIIGFSKALSKEVGSKNIRVNC 184
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
I PG I TD M + D K E+ K +PLGR+G PEEI FLAS+
Sbjct: 185 IAPGFIDTD-MTKGLSDNLK----------NEWLKGVPLGRVGTPEEIAMAALFLASNQS 233
Query: 245 SYINGAMIPVDGG 257
SYI G ++ VDGG
Sbjct: 234 SYITGQVLSVDGG 246
>gb|AAC44307.1| (U59433) 3-ketoacyl-acyl carrier protein reductase [Bacillus
subtilis]
Length = 246
Score = 127 bits (315), Expect = 2e-28
Identities = 81/254 (31%), Positives = 128/254 (49%), Gaps = 14/254 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVHYIV 64
L+ K A T +S+GIG +A LAK+GA+V++ S NE ++IK + +
Sbjct: 2 LNDKTAIVTGASRGIGRSIALALAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIA-VK 60
Query: 65 ADLTKMDDLERTVKELKNIGEP-DIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
AD++ +D++ +KE ++ DI + G + M M ++W++ + + L
Sbjct: 61 ADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNC 120
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TKA+ M ++ GRII +S+ P A + + GL ++ AKEL + ITVN
Sbjct: 121 TKAVTRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVN 180
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
I PG I TD +LA+D E K IPL R GEP ++ +V FLAS+
Sbjct: 181 AIAPGFISTDMTDKLAKD-----------VQDEMLKQIPLARFGEPSDVSSVVTFLASEG 229
Query: 244 GSYINGAMIPVDGG 257
Y+ G + +DGG
Sbjct: 230 ARYMTGQTLHIDGG 243
>sp|P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7430984|pir||A69621
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) [validated] - Bacillus subtilis
>gi|2633963|emb|CAB13464.1| (Z99112) 3-ketoacyl-acyl
carrier protein reductase [Bacillus subtilis]
Length = 246
Score = 125 bits (312), Expect = 4e-28
Identities = 81/254 (31%), Positives = 128/254 (49%), Gaps = 14/254 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVHYIV 64
L+ K A T +S+GIG +A LAK+GA+V++ S NE ++IK + +
Sbjct: 2 LNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIA-VK 60
Query: 65 ADLTKMDDLERTVKELKNIGEP-DIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
AD++ +D++ +KE ++ DI + G + M M ++W++ + + L
Sbjct: 61 ADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNC 120
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TKA+ M ++ GRII +S+ P A + + GL ++ AKEL + ITVN
Sbjct: 121 TKAVTRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVN 180
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
I PG I TD +LA+D E K IPL R GEP ++ +V FLAS+
Sbjct: 181 AIAPGFISTDMTDKLAKD-----------VQDEMLKQIPLARFGEPSDVSSVVTFLASEG 229
Query: 244 GSYINGAMIPVDGG 257
Y+ G + +DGG
Sbjct: 230 ARYMTGQTLHIDGG 243
>pir||C75151 oxidoreductase PAB0245 - Pyrococcus abyssi (strain Orsay)
>gi|5457800|emb|CAB49290.1| (AJ248284) OXIDOREDUCTASE
[Pyrococcus abyssi]
Length = 259
Score = 125 bits (312), Expect = 4e-28
Identities = 85/254 (33%), Positives = 133/254 (51%), Gaps = 7/254 (2%)
Query: 14 TASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTKMDDL 73
TA+S+GIGF +A+ L K G +V I S N +N+++A EK+KE E+HY ADL DD+
Sbjct: 6 TAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG--EIHYFKADLKSKDDI 63
Query: 74 ERTVKEL-KNIGEPDIFFFSTG--GPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKALVPA 130
+ +KE + +G D ++ G +P E DW EA L + Y+T L+ A
Sbjct: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123
Query: 131 -MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMPGI 189
+E+K G IIY +S ++ EP+P + L++ R + L + +++ G KGI ++ G
Sbjct: 124 WLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGS 183
Query: 190 IRTDRMIQLAQDRAKREGKTVEEALQ-EYAKPIPLGRLGEPEEIGYLVAFLASDLGSYIN 248
T + A+ G T++E + E PL R G E+G L+ FL S+ Y+
Sbjct: 184 FDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYML 243
Query: 249 GAMIPVDGGRLNSV 262
G+ I DG V
Sbjct: 244 GSTIVFDGAMTRGV 257
>sp|P50941|FABG_RICPR 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7430988|pir||F71636 3-oxoacyl
reductase (fabG) RP762 - Rickettsia prowazekii
>gi|3861291|emb|CAA15190.1| (AJ235273) 3-OXOACYL
REDUCTASE (fabG) [Rickettsia prowazekii]
Length = 241
Score = 125 bits (312), Expect = 4e-28
Identities = 80/256 (31%), Positives = 128/256 (49%), Gaps = 18/256 (7%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
IDL+GK + T +S GIG +AR+L K G+ VII NEE LK +K+ +EV
Sbjct: 2 IDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEV--- 58
Query: 64 VADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+L ++ + + N+ DI + G + M +D+++ + + L L
Sbjct: 59 -CNLANKEECSNLISKTSNL---DILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFIL 114
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+ + M +K +GRII +S+ P A + + G+ ++L+ E+ +GITVN
Sbjct: 115 NREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVN 174
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG I++D K E+ + + IPLG G PE++ Y VAFLAS+
Sbjct: 175 AVAPGFIKSD-----------MTDKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNN 223
Query: 244 GSYINGAMIPVDGGRL 259
SYI G + V+GG L
Sbjct: 224 ASYITGQTLHVNGGML 239
>pir||D72377 oxidoreductase, short chain dehydrogenase/reductase family -
Thermotoga maritima (strain MSB8)
>gi|4980948|gb|AAD35526.1|AE001722_10 (AE001722)
oxidoreductase, short chain dehydrogenase/reductase
family [Thermotoga maritima]
Length = 255
Score = 124 bits (308), Expect = 1e-27
Identities = 79/255 (30%), Positives = 131/255 (50%), Gaps = 11/255 (4%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL G++A T S+G+GFG+A+ LA+AG V++ SRN E A +K+ E+ VE
Sbjct: 6 DLRGRVALVTGGSRGLGFGIAQGLAEAGCSVVVASRNLEEASEAAQKLTEKYGVETMAFR 65
Query: 65 ADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D++ +++++ ++ +K G+ D + G + E ++++ + +++ L+ Y+
Sbjct: 66 CDVSNYEEVKKLLEAVKEKFGKLDTVVNAAGINRRHPAEEFPLDEFRQVIEVNLFGTYYV 125
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKE-PIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+ + II S+ ++E +PNI+ + +A L + LAKE G GI V
Sbjct: 126 CREAFSLLRESDNPSIINIGSLTVEEVTMPNISAYAASKGGVASLTKALAKEWGRYGIRV 185
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG RT + D E L K IPLGR G PE++ + FLAS+
Sbjct: 186 NVIAPGWYRTKMTEAVFSD---------PEKLDYMLKRIPLGRTGVPEDLKGVAVFLASE 236
Query: 243 LGSYINGAMIPVDGG 257
Y+ G +I VDGG
Sbjct: 237 EAKYVTGQIIFVDGG 251
>gb|AAF51983.1| (AE003602) CG2907 gene product [Drosophila melanogaster]
Length = 264
Score = 123 bits (307), Expect = 2e-27
Identities = 77/257 (29%), Positives = 132/257 (50%), Gaps = 9/257 (3%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+D SGK+ T ++ GIG A + +K GA + ++ R EE L ++ + + E + I
Sbjct: 9 LDFSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGH-EPYGI 67
Query: 64 VADLTKMDDLERTVKEL--KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
DL K ++E ++ + G+ D+ G G + + ++ +
Sbjct: 68 AGDLLKPPEIECIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANVRSGF 127
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
YLTK L+P + + G I+ +SV PN+ N+ + A+ R+LA +LGP+G+
Sbjct: 128 YLTKLLLPQLLQCK-GSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVR 186
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG+IRT+ Q + ++ E L+ K LGR+GEP+E+ + FLAS
Sbjct: 187 VNAVNPGVIRTN-----LQKAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLAS 241
Query: 242 DLGSYINGAMIPVDGGR 258
+L S++ G +PVDGG+
Sbjct: 242 ELASFVTGVTLPVDGGK 258
>sp|O54438|FABG_PSEAE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7431039|pir||T12020
3-oxoacyl-acyl carrier protein reductase - Pseudomonas
aeruginosa >gi|11347291|pir||B83276
3-oxoacyl-[acyl-carrier-protein PA2967 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|2738155|gb|AAB94395.1| (U91631) 3-oxoacyl-acyl
carrier protein reductase [Pseudomonas aeruginosa]
>gi|9949065|gb|AAG06355.1|AE004722_11 (AE004722)
3-oxoacyl-[acyl-carrier-protein [Pseudomonas aeruginosa]
Length = 247
Score = 123 bits (305), Expect = 3e-27
Identities = 84/257 (32%), Positives = 137/257 (52%), Gaps = 17/257 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ L GK+A T +S+GIG +A L + GA VI + + ++ E +K + VE +
Sbjct: 1 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKA-NGVEGAGL 59
Query: 64 VADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
V D++ + + T++ ++ ++G+P I + G + + M ++W + V L
Sbjct: 60 VLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYR 119
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKGI 180
L+KA++ M + +GRII SV + N +N + + G R LA+E+G + I
Sbjct: 120 LSKAVLRGMTKARWGRIINIGSVV--GAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAI 177
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + PG I TD +L + A+RE + IPLGRLG+ EEI +V FLA
Sbjct: 178 TVNAVAPGFIDTDMTRELPE--AQREALLGQ---------IPLGRLGQAEEIAKVVGFLA 226
Query: 241 SDLGSYINGAMIPVDGG 257
SD +Y+ GA +PV+GG
Sbjct: 227 SDGAAYVTGATVPVNGG 243
>sp|P38004|FABG_CHLTR 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7430986|pir||F71538 probable
oxoacyl (carrier protein) reductase - Chlamydia
trachomatis (serotype D, strain UW3/Cx)
>gi|3328647|gb|AAC67830.1| (AE001297) Oxoacyl (Carrier
Protein) Reductase [Chlamydia trachomatis]
Length = 248
Score = 123 bits (305), Expect = 3e-27
Identities = 82/253 (32%), Positives = 122/253 (47%), Gaps = 12/253 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L K A T S+GIGF +A++ A+ GA+V I N E + A + + E++ +V + +
Sbjct: 5 LVNKTAIVTGGSRGIGFSIAKLFAEQGANVQIWGINGEAGQAAAQTLSEQTGRQVSFALV 64
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D++K D + V+ L D+ + G + M MS E+W + L +
Sbjct: 65 DVSKNDMVSAQVQNFLAEYNTIDVIVNNAGITRDALLMRMSEEEWSSVINTNLGSIYNVC 124
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
A++ M + G II +S+ P + + G + L+KE+G K I VN
Sbjct: 125 SAVIRPMIKARSGAIINISSIVGLRGSPGQTNYAAAKAGIIGFSKALSKEVGSKNIRVNC 184
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
I PG I TD M + D K E + K +PLGR+G PEEI FLASD
Sbjct: 185 IAPGFIDTD-MTKSLNDNLKNE----------WLKGVPLGRVGMPEEIAKAALFLASDGS 233
Query: 245 SYINGAMIPVDGG 257
SYI G ++ VDGG
Sbjct: 234 SYITGQVLSVDGG 246
>pir||A83207 probable short-chain dehydrogenase PA3507 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949654|gb|AAG06895.1|AE004771_4 (AE004771) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 265
Score = 122 bits (302), Expect = 6e-27
Identities = 81/262 (30%), Positives = 131/262 (49%), Gaps = 7/262 (2%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE-SNVE 59
M DLS +A T S GIG +L +AGA V +R+ E L+ A +++
Sbjct: 1 MKPYDLSEAVAVVTGGSSGIGLATVELLLEAGAAVAFCARDGERLRAAESALRQRFPGAR 60
Query: 60 VHYIVADLTKMDDLE-RTVKEL--KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLL 116
+ V D+ +D L+ R E + +G I + G + F E + E W E ++L
Sbjct: 61 LFASVCDV--LDALQVRAFAEACERTLGCASILVNNAGQGRVSTFAETTDEAWSEELQLK 118
Query: 117 LYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELG 176
+ I+ +A +P +E + I+ S+ +P P++ ++ R + LVR++A E
Sbjct: 119 FFSVIHPVRAFLPQLESRADAAIVCVNSLLASQPEPHMVATSAARAGVKNLVRSMAFEFA 178
Query: 177 PKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQ-EYAKPIPLGRLGEPEEIGYL 235
PKG+ VNGI+ G++ + + + + R +RE + Q K IPLGRLG+P E
Sbjct: 179 PKGVRVNGILIGLVESGQWRRRFEAREERELDWAQWTAQLARNKQIPLGRLGKPIEAARA 238
Query: 236 VAFLASDLGSYINGAMIPVDGG 257
+ FLAS L +Y G+ I V GG
Sbjct: 239 ILFLASPLSAYTTGSHIDVSGG 260
>sp|P37440|UCPA_ECOLI OXIDOREDUCTASE UCPA >gi|7427657|pir||A65017 probable
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) yfeF - Escherichia coli (strain K-12)
>gi|1788766|gb|AAC75479.1| (AE000330) putative
oxidoreductase [Escherichia coli K12]
>gi|1799855|dbj|BAA16309.1| (D90872) similar to
[SwissProt Accession Number P37440] [Escherichia coli]
Length = 285
Score = 121 bits (301), Expect = 8e-27
Identities = 86/254 (33%), Positives = 130/254 (50%), Gaps = 7/254 (2%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK A T + +GIG G+AR A+ GA++I+L + E K A E +VA
Sbjct: 26 LTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEKLADELCGRGHRCTA--VVA 83
Query: 66 DLTKMDDLERTVKELKNI-GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+ + +K K G DI + G + G F++MS +D + + + + +T
Sbjct: 84 DVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDDDRDFHIDINIKGVWNVT 143
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPI-PNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
KA++P M + GRI+ +SV P + + A+ GL ++LA E GI VN
Sbjct: 144 KAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQSGIRVN 203
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
I PG +RT +A+ + ++V L E AK IP+ RL +P E+G L AFLASD
Sbjct: 204 AICPGYVRTPMAESIARQSNPEDPESV---LTEMAKAIPMRRLADPLEVGELAAFLASDE 260
Query: 244 GSYINGAMIPVDGG 257
SY+ G +DGG
Sbjct: 261 SSYLTGTQNVIDGG 274
>gb|AAF50801.1| (AE003567) CG10672 gene product [Drosophila melanogaster]
Length = 317
Score = 121 bits (300), Expect = 1e-26
Identities = 78/254 (30%), Positives = 138/254 (53%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK+A TAS+ GIGF +A+ LA+ GA V+I SR ++N+ A ++++ N+ VH +
Sbjct: 69 LAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRK-LNLNVHGLKC 127
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+++ +D ++ +E + G+ +I + P G +E + W++ + + + L
Sbjct: 128 HVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLL 187
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
K +P + ++ I++ +S+A + + +V + A+ GL + AK+L P+GI VN
Sbjct: 188 AKEALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVN 247
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG+IRT +A E ++ EA IP+GRLG EE+ +V+FL S+
Sbjct: 248 CLAPGVIRT------KFSKALYENESANEAA---LSKIPMGRLGTSEEMAGVVSFLVSED 298
Query: 244 GSYINGAMIPVDGG 257
YI G I GG
Sbjct: 299 AGYITGESIVAGGG 312
>emb|CAA68181.1| (X99908) belongs to alcohol dehydrogenase /rybitol dehydrogenase
family [Escherichia coli]
Length = 263
Score = 121 bits (300), Expect = 1e-26
Identities = 86/254 (33%), Positives = 130/254 (50%), Gaps = 7/254 (2%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK A T + +GIG G+AR A+ GA++I+L + E K A E +VA
Sbjct: 4 LTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEKLADELCGRGHRCTA--VVA 61
Query: 66 DLTKMDDLERTVKELKNI-GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+ + +K K G DI + G + G F++MS +D + + + + +T
Sbjct: 62 DVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDDDRDFHIDINIKGVWNVT 121
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPI-PNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
KA++P M + GRI+ +SV P + + A+ GL ++LA E GI VN
Sbjct: 122 KAVLPEMIARKDGRIVMMSSVTGDMVADPGEQAYALTKAAIVGLTKSLAVEYAQSGIRVN 181
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
I PG +RT +A+ + ++V L E AK IP+ RL +P E+G L AFLASD
Sbjct: 182 AICPGYVRTPMAESIARQSNPEDPESV---LTEMAKAIPMRRLADPLEVGELAAFLASDE 238
Query: 244 GSYINGAMIPVDGG 257
SY+ G +DGG
Sbjct: 239 SSYLTGTQNVIDGG 252
>sp|P43713|FABG_HAEIN 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|1073790|pir||D64051
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) - Haemophilus influenzae (strain Rd KW20)
>gi|1573112|gb|AAC21824.1| (U32701) 3-ketoacyl-acyl
carrier protein reductase (fabG) [Haemophilus influenzae
Rd]
Length = 242
Score = 120 bits (298), Expect = 2e-26
Identities = 80/253 (31%), Positives = 129/253 (50%), Gaps = 16/253 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
+ GK+A T S++GIG +A L+ GA VI + +E+ + + ++ +V
Sbjct: 1 MQGKIALVTGSTRGIGRAIAEELSSKGAFVIGTATSEKGAEAISAYLGDKGKG----LVL 56
Query: 66 DLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
++T + +E ++++KN G+ DI + G + M M E+W + ++ L +L+
Sbjct: 57 NVTDKESIETLLEQIKNDFGDIDILVNNAGITRDNLLMRMKDEEWFDIMQTNLTSVYHLS 116
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
KA++ +M +K FGRII SV P + + G ++LAKE+ +GITVN
Sbjct: 117 KAMLRSMMKKRFGRIINIGSVVGSTGNPGQTNYCAAKAGVVGFSKSLAKEVAARGITVNV 176
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
+ PG I TD M ++ D K +P GRLGE ++I VAFLASD
Sbjct: 177 VAPGFIATD-MTEVLTDEQK----------AGILSNVPAGRLGEAKDIAKAVAFLASDDA 225
Query: 245 SYINGAMIPVDGG 257
YI G + V+GG
Sbjct: 226 GYITGTTLHVNGG 238
>dbj|BAA36159.1| (AB009078) L-2.3-butanediol dehydrogenase [Brevibacterium
saccharolyticum]
Length = 258
Score = 120 bits (298), Expect = 2e-26
Identities = 75/255 (29%), Positives = 137/255 (53%), Gaps = 5/255 (1%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIK--EESNVEVHYIVAD 66
K+A T ++GIG G++ LA G D+ + ++ ++A E IK E ++ + ++ D
Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQE-EQAAETIKLIEAADQKAVFVGLD 61
Query: 67 LTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
+T + + + E + +G D+ + G + +E++ ED ++ + ++ + +
Sbjct: 62 VTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQ 121
Query: 126 ALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
A + G G+II + S+A + P ++ + + A+ GL + A+EL PKG TVN
Sbjct: 122 AASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNA 181
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
PGI+ T Q+ + +K GK + E +EY+ I LGR PE++ LV+FLAS+
Sbjct: 182 YAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASENS 241
Query: 245 SYINGAMIPVDGGRL 259
+Y+ G ++ VDGG L
Sbjct: 242 NYVTGQVMLVDGGML 256
>gb|AAC38801.1| (AF030176) putative short-chain dehydrogenase/reductase
[Rhodococcus opacus]
Length = 269
Score = 119 bits (296), Expect = 3e-26
Identities = 82/260 (31%), Positives = 131/260 (49%), Gaps = 9/260 (3%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVE-VHYI 63
+L G+ A T S+G+GF +A+ L + GA V I++R++ +K A ++ + + V I
Sbjct: 6 NLDGRTALVTGGSRGLGFSIAQALLERGAKVAIIARDDAAVKAAAGRLDSGAGAQNVLPI 65
Query: 64 VADLTKMDDLERTVKELKNI-GEPDIFFFSTG---GPKPGYFMEMSMEDWEEAVKLLLYP 119
VAD+ D + + ++ G DI + G P P + ++ KLL +
Sbjct: 66 VADVADSDSIHEALAQVHEWQGRLDIVVNNAGPQLAPSPVTDADENVLTSAFDTKLLGF- 124
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+ ++KA +P + + G G I+ PIPN ++ +V ++ L LA E K
Sbjct: 125 -LRVSKAALPFLSQDGTGSIVNVAGATAHVPIPNTGVTGIVNASVVALTSFLATEAAAKN 183
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAK--PIPLGRLGEPEEIGYLVA 237
I VN I PG+ +T+ + A+++ KT +E + I LGR EP EIG A
Sbjct: 184 IRVNAISPGMTKTEGWLAKNDAAAQQQDKTADEIRAGVVQGLGIRLGRWAEPAEIGAAAA 243
Query: 238 FLASDLGSYINGAMIPVDGG 257
FLASD SYI G ++ VDGG
Sbjct: 244 FLASDDASYITGQVLRVDGG 263
>dbj|BAB04651.1| (AP001510) 3-oxoacyl-(acyl-carrier protein) reductase [Bacillus
halodurans]
Length = 252
Score = 118 bits (294), Expect = 5e-26
Identities = 83/263 (31%), Positives = 132/263 (49%), Gaps = 12/263 (4%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ + L K+ T SKGIG G+A+ + GA V I++R+ L+ A+ ++ ++
Sbjct: 1 MDLQLKDKVVLVTGGSKGIGKGIAQAFVEEGAKVAIVARDAHGLQEAKRQLGNVLTIQ-- 58
Query: 62 YIVADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
AD+T ++ E+ +L + G DI + GG G E + +EEA L + A
Sbjct: 59 ---ADVTDKNEREKVFSQLLETYGTIDILVNNAGGSNGGLISETELSLFEEAFSLNYFSA 115
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
++ ++ +P M+ K G II +S+ +E A N + AM ++LA E+ GI
Sbjct: 116 VHFSQLALPVMKAKQSGAIINISSIFGRES-GGKATYNSAKAAMISFTKSLADEVIRDGI 174
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VNGI PG I + + KR + E+ Q + IP GR G EEI + FLA
Sbjct: 175 RVNGIAPGSI-----LHPTGNWQKRLEENREKMEQFIDQNIPAGRFGTVEEIANVAVFLA 229
Query: 241 SDLGSYINGAMIPVDGGRLNSVF 263
S+ S++ GA + VDGG+ S F
Sbjct: 230 SEKASWVVGATLNVDGGQSYSNF 252
>emb|CAB65876.1| (AL109630) /match=(desc:""3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (EC 1.1.1.100) (3-KETOACYL- ACYL CARRIER
PROTEIN REDUCTASE)"", species:""Escherichia coli"",
ranges:(query:124808..124897,
target:SWISS-PROT::P25716:30..1, score:""84.00""),
(query:12>
Length = 251
Score = 118 bits (293), Expect = 7e-26
Identities = 78/260 (30%), Positives = 133/260 (51%), Gaps = 16/260 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ LS K+ T +S GIG +A+VLA+ GA + ++ RN NL+ ++ +K + +
Sbjct: 1 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLK---GTQAEIV 57
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
VAD+TK D + V++ L G D+ + G G +++ +E+++ + L I
Sbjct: 58 VADVTK--DADAIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVIL 115
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
LTKA++P + K G ++ +S A P V + A+ + +A E+ P+G+ V
Sbjct: 116 LTKAVLPHL-LKTKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRV 174
Query: 183 NGIMPGIIRTD--RMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
N + PG + T+ R I + + LQ P+GR+G+ E+ VAFLA
Sbjct: 175 NSVNPGFVVTNIHRNIGIVDEE-------YNGMLQRAINSHPMGRVGDVTEVAEAVAFLA 227
Query: 241 SDLGSYINGAMIPVDGGRLN 260
S S+ GA+ P+DGG+ N
Sbjct: 228 SSKASFTTGALFPIDGGKHN 247
>gb|AAG34187.1|AF321122_6 (AF321122) Sim-nJ1 [Streptomyces antibioticus]
Length = 273
Score = 118 bits (293), Expect = 7e-26
Identities = 85/251 (33%), Positives = 121/251 (47%), Gaps = 11/251 (4%)
Query: 10 LAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTK 69
+A T + +GIG A+ LA GA V ++ R E + I+ + I D+T
Sbjct: 29 VAIVTGAGRGIGAATAQRLAAEGATVAVVDRTEADTADTVASIRAAGGRALG-IGCDVTV 87
Query: 70 MDDLERTV-KELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKALV 128
D +E V + + G D+ + G + M EDW+ + + L A +A
Sbjct: 88 TDLVEAAVDRTVAEFGRLDVLVNNAGVTRDSLVFMMGDEDWDTVIDVHLNGAARTVRAAR 147
Query: 129 PAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKGITVNGIM 186
M R+G GRI+ +S+A + N +N + A+ G RTLA ELGP GITVN I
Sbjct: 148 RQMVRQGSGRIVNLSSIAA---LGNQGQANYATAKAAIQGYTRTLAVELGPHGITVNAIA 204
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PG I T + D A+R G + A +P+ R+G PE+I LVAFLA SY
Sbjct: 205 PGFIATT----MTDDTARRMGSDPVALRKAVASRVPMRRVGRPEDIAGLVAFLAGPDASY 260
Query: 247 INGAMIPVDGG 257
+ G I VDGG
Sbjct: 261 LTGQTIYVDGG 271
>pir||A71192 probable glucose 1-dehydrogenase - Pyrococcus horikoshii
>gi|3258245|dbj|BAA30928.1| (AP000007) 261aa long
hypothetical glucose 1-dehydrogenase [Pyrococcus
horikoshii]
Length = 261
Score = 117 bits (290), Expect = 1e-25
Identities = 81/254 (31%), Positives = 131/254 (50%), Gaps = 7/254 (2%)
Query: 14 TASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTKMDDL 73
TASS+GIGF +A+ L G +V I S N N++ A ++++E V HY ADL+ +D+
Sbjct: 8 TASSRGIGFNLAKELLNKGHEVTITSSNIRNIENAYKELRELGTV--HYFQADLSSKEDI 65
Query: 74 ERTVKELKN-IGEPDIFFFSTGGPK--PGYFMEMSMEDWEEAVKLLLYPAIYLTKALVPA 130
+R VK+ + +G + ++ K P E DW EA L L Y+T L+ A
Sbjct: 66 KRMVKDAWDAMGRIEALIWNAPNVKCEPCMVHEARYRDWLEAALLHLVSPGYITTLLIQA 125
Query: 131 -MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMPGI 189
+E+K G +IY +S ++ EP+P + L++ R + L + + + G KGI ++ G
Sbjct: 126 WLEKKIKGVLIYLSSASVLEPMPPLLLADTARAGLVQLTKGITRAYGGKGIRAYVVLLGS 185
Query: 190 IRTDRMIQLAQDRAKREGKTVEEA-LQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSYIN 248
T + A+ G ++EE +E + PL R G+ E+G L+ FL S+ Y+
Sbjct: 186 FDTPGARENLAKIAEERGMSLEEIWRKEVIERTPLKRTGKWSELGALIDFLLSENAEYMM 245
Query: 249 GAMIPVDGGRLNSV 262
G+ I DG V
Sbjct: 246 GSTILFDGAMTRGV 259
>pir||G75333 3-oxoacyl-acyl carrier protein reductase - Deinococcus radiodurans
(strain R1) >gi|6459730|gb|AAF11496.1|AE002033_4
(AE002033) 3-oxoacyl-acyl carrier protein reductase
[Deinococcus radiodurans]
Length = 254
Score = 117 bits (290), Expect = 1e-25
Identities = 82/251 (32%), Positives = 121/251 (47%), Gaps = 14/251 (5%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVHYIVADL 67
++A T SS+G+G +A LA+ G V + R E ++ I+ ADL
Sbjct: 12 RVALVTGSSRGLGRAMALRLAQDGFTVAVHYGRGEAEAQQVAADIRAAGGA-AQVFGADL 70
Query: 68 TKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKA 126
++ + V++ + +G D+ + G + G + M EDW+ ++ L A +A
Sbjct: 71 SQPANAGTLVEDVIAALGRLDVLVNNAGITRDGLAIRMKDEDWDAVLQTNLSSAFAACRA 130
Query: 127 LVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
+ M + GRI+ +SV P A + + GL R LAKE G +GITVN I
Sbjct: 131 ALKHMMKNRSGRIVNVSSVVALAGNPGQANYVASKAGLIGLTRALAKEYGGRGITVNAIA 190
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PG I +D +L +D K +Y IPL R G+PEE+ LVAFLAS+ Y
Sbjct: 191 PGFIESDMTAKLPEDTKK-----------QYQANIPLARFGQPEEVAALVAFLASEGAGY 239
Query: 247 INGAMIPVDGG 257
I G I VDGG
Sbjct: 240 ITGQTIGVDGG 250
>pir||F81971 probable 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
NMA0533 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|7379273|emb|CAB83827.1| (AL162753)
putative 3-oxoacyl-[acyl-carrier protein] reductase
[Neisseria meningitidis Z2491]
Length = 248
Score = 117 bits (290), Expect = 1e-25
Identities = 81/258 (31%), Positives = 127/258 (48%), Gaps = 19/258 (7%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DLSGK+A T +S+GIG +A LA AGA VI + +E E++ +
Sbjct: 5 DLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGG---EGRA 61
Query: 65 ADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D + + +E + ++ K G+ DI + G + M M E+W++ +++ L
Sbjct: 62 LDSAEPETIESLIADIEKAFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRA 121
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKGIT 181
+KA++ M ++ GRII TSV + N +N + + G +++A+E+G +GIT
Sbjct: 122 SKAVLRGMMKQRSGRIINITSVV--GVMGNAGQTNYAAAKAGLIGFAKSMAREVGSRGIT 179
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG I TD L EE Q + LGR G+ ++I V FLAS
Sbjct: 180 VNCVAPGFIDTDMTRALP-----------EETRQAFTAQTALGRFGDAQDIADAVLFLAS 228
Query: 242 DLGSYINGAMIPVDGGRL 259
D YI G + V+GG L
Sbjct: 229 DQAKYITGQTLHVNGGML 246
>pir||H83476 probable short-chain dehydrogenase PA1344 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947285|gb|AAG04733.1|AE004564_2 (AE004564) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 264
Score = 116 bits (289), Expect = 2e-25
Identities = 78/268 (29%), Positives = 138/268 (51%), Gaps = 12/268 (4%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKE-ESNVEV 60
++IDLS KLA + S+ GIGF +A LA AGA V++ R++ + RA I+ + + V
Sbjct: 1 MQIDLSDKLAIVSGSTAGIGFAIASGLAAAGATVVVNGRSQAAVDRAIAAIRNGQPDARV 60
Query: 61 HYIVADLTKMDDLERTVKELKNIGEP--DIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLY 118
+ DL + V EP DI + G + F ++ +W ++ +
Sbjct: 61 RGVAGDLGTAEGCAAFV-----AAEPKADILVNNLGIFELKDFFDIEDAEWSRFFEVNVM 115
Query: 119 PAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
+ L +A VP M +G+GR+++ +S + ++ + A + R LAK L
Sbjct: 116 SGVRLARAYVPGMVERGWGRVVFLSSESALNIPADMIHYGFSKTANLSVSRGLAKRLAGT 175
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEA----LQEYAKPIPLGRLGEPEEIGY 234
G+TVN ++PG T+ + ++ ++ A++ G+++EEA ++++ + RL PEE+
Sbjct: 176 GVTVNAVLPGPTLTEGVAEMLREDAQKAGQSIEEAGTAFVRQHRSSSIIQRLATPEEVAN 235
Query: 235 LVAFLASDLGSYINGAMIPVDGGRLNSV 262
LV + S S GA + VDGG L+S+
Sbjct: 236 LVVYTCSTQASATTGAALRVDGGVLDSL 263
>sp|P39644|YWFH_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PTA-ROCC INTERGENIC REGION
>gi|2126976|pir||S39741 3-oxoacyl- acyl-carrier protein
reductase homolog ywfH - Bacillus subtilis
>gi|580882|emb|CAA51642.1| (X73124) ipa-86r [Bacillus
subtilis] >gi|2636304|emb|CAB15795.1| (Z99123) alternate
gene name: ipa-86r~similar to 3-oxoacyl- acyl-carrier
protein reductase [Bacillus subtilis]
Length = 259
Score = 115 bits (286), Expect = 4e-25
Identities = 76/259 (29%), Positives = 126/259 (48%), Gaps = 2/259 (0%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKI-KEESNVEVHYIV 64
+S + AF +S+GIG +A LA ++I SRN +N++ +E I + V +
Sbjct: 1 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLA 60
Query: 65 ADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D++ +++++ G D+ + G P F ++ED I
Sbjct: 61 GDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDA 120
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
K M++ FGRII KEP N+ ++++ A+ + ++ +L P ITVN
Sbjct: 121 IKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVN 180
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG I TDR Q ++ K+ + ++A ++ A IP+ R+G EE L AFLAS+
Sbjct: 181 CLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEE 240
Query: 244 GSYINGAMIPVDGGRLNSV 262
SYI G I DGG + S+
Sbjct: 241 ASYITGQQISADGGSMKSI 259
>pir||H70046 probable 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)
yvrD - Bacillus subtilis >gi|2635816|emb|CAB15309.1|
(Z99120) similar to ketoacyl-carrier protein reductase
[Bacillus subtilis] >gi|2635832|emb|CAB15324.1| (Z99121)
similar to ketoacyl-carrier protein reductase [Bacillus
subtilis] >gi|2832810|emb|CAA11734.1| (AJ223978)
putative ketoreductase, YvrD [Bacillus subtilis]
Length = 263
Score = 115 bits (286), Expect = 4e-25
Identities = 75/265 (28%), Positives = 133/265 (49%), Gaps = 6/265 (2%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ + L KL T S+ GIG A+ + GA VI+ R +E + R E++ V H
Sbjct: 1 MDLQLKEKLVLITGSTSGIGKAAAKSFLQEGAAVIVNGRKQETVDRTIEELSGYGTV--H 58
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
ADL+K D+ ++++ IG+ DI + G + F +++ E+W + ++ + A+
Sbjct: 59 GAAADLSKTDEAAAFIEKVNEIGDIDILVNNLGFFEVKDFADVTDEEWNQYFEVNVMSAV 118
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ +P M K GRI+ S A +P+P + ++ + A+ L R +A+ +T
Sbjct: 119 RTSRHFLPKMLAKNSGRILNIASEAGVKPLPTMIPYSMTKTALISLSRGMAEMTKGTNVT 178
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAK---PIPL-GRLGEPEEIGYLVA 237
VN ++PG T+ + + A+ G+ + +++Y K P L R EE+ +
Sbjct: 179 VNSVLPGPTWTEGVASYMEGAAQAAGQDTDTFIKDYFKVNEPTSLIQRYATAEEVANTIV 238
Query: 238 FLASDLGSYINGAMIPVDGGRLNSV 262
FLASD S ING V+GG + S+
Sbjct: 239 FLASDAASAINGTAQRVEGGIIRSL 263
>pir||A72395 oxidoreductase, short chain dehydrogenase/reductase family -
Thermotoga maritima (strain MSB8)
>gi|4980796|gb|AAD35385.1|AE001711_8 (AE001711)
oxidoreductase, short chain dehydrogenase/reductase
family [Thermotoga maritima]
Length = 257
Score = 115 bits (285), Expect = 6e-25
Identities = 85/256 (33%), Positives = 127/256 (49%), Gaps = 16/256 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L K+A T +GIG +A+ LA AGA V+I+ NEE +R E+IKE+ E + V
Sbjct: 10 LKRKVALVTGGGQGIGKAIAQALAAAGAAVLIMDINEETARRTVEEIKEKGG-EADFYVG 68
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+TK +D VK+ L G+ DI + G +E W++ + + L
Sbjct: 69 DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128
Query: 125 KALVPAMERKGFGRIIYSTSVA---IKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
KA AM+ + +G+II S++ + +P A N + + L R+LA E P GI
Sbjct: 129 KAEFHAMKERKYGKIINIASMSGHIVNKPQKQTAY-NASKAGVIHLTRSLAAEWAPYGIR 187
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN I PG IRT + E V++ + + IPLGRLGE +++ FLAS
Sbjct: 188 VNSISPGYIRTPLI----------ESPNVKDLVPLWLDMIPLGRLGEVDDLIGAAIFLAS 237
Query: 242 DLGSYINGAMIPVDGG 257
Y+ G + +DGG
Sbjct: 238 PASDYMTGHDLVIDGG 253
>sp|P25716|FABG_ECOLI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7427650|pir||B42147
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) - Escherichia coli
>gi|1651536|dbj|BAA35901.1| (D90745)
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100). [Escherichia coli]
>gi|1787335|gb|AAC74177.1| (AE000210)
3-oxoacyl-[acyl-carrier-protein] reductase [Escherichia
coli K12]
Length = 244
Score = 115 bits (284), Expect = 7e-25
Identities = 80/255 (31%), Positives = 126/255 (49%), Gaps = 16/255 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++ GK+A T +S+GIG +A LA GA VI + +E + I + +
Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGA----QAISDYLGANGKGL 56
Query: 64 VADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
+ ++T +E +++++ GE DI + G + M M E+W + ++ L
Sbjct: 57 MLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFR 116
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L+KA++ AM +K GRII SV A + + G ++LA+E+ +GITV
Sbjct: 117 LSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITV 176
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I TD L+ D+ R G + +P GRLG +EI VAFLASD
Sbjct: 177 NVVAPGFIETDMTRALSDDQ--RAGILAQ---------VPAGRLGGAQEIANAVAFLASD 225
Query: 243 LGSYINGAMIPVDGG 257
+YI G + V+GG
Sbjct: 226 EAAYITGETLHVNGG 240
>pir||E81026 3-oxoacyl-(acyl-carrier-protein) reductase NMB1921 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7227179|gb|AAF42251.1| (AE002541)
3-oxoacyl-(acyl-carrier-protein) reductase [Neisseria
meningitidis MC58]
Length = 248
Score = 115 bits (284), Expect = 7e-25
Identities = 80/258 (31%), Positives = 128/258 (49%), Gaps = 19/258 (7%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL+GK+A T +S+GIG +A LA AGA VI + +E E++ + V
Sbjct: 5 DLNGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGG---EGRV 61
Query: 65 ADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ + + +E + ++ K G+ DI + G + M M E+W++ +++ L
Sbjct: 62 LNSAEPETIESLIADIEKAFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRA 121
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKGIT 181
+KA++ M ++ GRII TSV + N +N + + G +++A+E+G +GIT
Sbjct: 122 SKAVLRGMMKQRSGRIINITSVV--GVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGIT 179
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG I TD L EE Q + LGR G+ ++I V FLAS
Sbjct: 180 VNCVAPGFIDTDMTRALP-----------EETRQTFTAQTALGRFGDAQDIADAVLFLAS 228
Query: 242 DLGSYINGAMIPVDGGRL 259
D YI G + V+GG L
Sbjct: 229 DQAKYITGQTLHVNGGML 246
>sp|O85141|FABG_SALTY 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|3282804|gb|AAC38650.1| (AF044668)
3-oxoacyl-acyl carrier protein reductase [Salmonella
typhimurium]
Length = 244
Score = 114 bits (282), Expect = 1e-24
Identities = 80/255 (31%), Positives = 123/255 (47%), Gaps = 16/255 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ GK+A T +S+GIG +A L GA VI + +E K I + +
Sbjct: 1 MSFEGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKN----ISDYLGANGKGL 56
Query: 64 VADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
+ ++T +E ++ ++ GE DI + G + M M ++W + ++ L
Sbjct: 57 MLNVTDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSSVFR 116
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L+KA++ AM +K GRII SV A + + G ++LA+E+ +GITV
Sbjct: 117 LSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGITV 176
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I TD L+ D+ R G + +P GRLG +EI VAFLASD
Sbjct: 177 NVVAPGFIETDMTRALSDDQ--RAGILAQ---------VPAGRLGGAQEIASAVAFLASD 225
Query: 243 LGSYINGAMIPVDGG 257
SYI G + V+GG
Sbjct: 226 EASYITGETLHVNGG 240
>sp|P55336|FABG_VIBHA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7431040|pir||T12051
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) - Vibrio harveyi >gi|1173841|gb|AAC43589.1|
(U39441) 3-ketoacyl-ACP reductase [Vibrio harveyi]
Length = 244
Score = 113 bits (281), Expect = 2e-24
Identities = 77/257 (29%), Positives = 127/257 (48%), Gaps = 20/257 (7%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++L GK+A T +S+GIG +A +L + GA VI + +E E + E +
Sbjct: 1 MNLEGKIALVTGASRGIGRAIAELLVERGATVIGTATSEGGAAAISEYLGENGKG----L 56
Query: 64 VADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
++T ++ +E T+K + + G DI + G + M M ++W + + L P
Sbjct: 57 ALNVTDVESIEATLKTINDECGAIDILVNNAGITRDNLLMRMKDDEWNDIINTNLTPIYR 116
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKGI 180
++KA++ M +K GRII SV + N +N + + G +++A+E+ +G+
Sbjct: 117 MSKAVLRGMMKKRAGRIINVGSVV--GTMGNAGQTNYAAAKAGVIGFTKSMAREVASRGV 174
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + PG I TD L D+ T+ +P GRLG+P EI V FLA
Sbjct: 175 TVNTVAPGFIETDMTKALNDDQ---RAATLSN--------VPAGRLGDPREIASAVVFLA 223
Query: 241 SDLGSYINGAMIPVDGG 257
S +YI G + V+GG
Sbjct: 224 SPEAAYITGETLHVNGG 240
>pir||E70027 probable 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)
yvaG - Bacillus subtilis >gi|2635872|emb|CAB15364.1|
(Z99121) similar to 3-oxoacyl- acyl-carrier protein
reductase [Bacillus subtilis]
Length = 264
Score = 113 bits (281), Expect = 2e-24
Identities = 85/268 (31%), Positives = 132/268 (48%), Gaps = 10/268 (3%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+K++L GK A T S+ GIG +A LA+ GA VII R EE + + +++K + V
Sbjct: 1 MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVL 60
Query: 62 YIVA-DLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
Y A DL E EL + E DI + G +P + ++ ++W ++ +
Sbjct: 61 YPAAFDL----GTEEGCNELFQAYPEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMS 116
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+ LT+ + M K GR+I+ S A P +A + + + R+LA+
Sbjct: 117 GVRLTRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSISRSLAELATGTN 176
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEA----LQEYAKPIPLGRLGEPEEIGYL 235
+TVN +MPG T+ + + E TV+EA ++E + RL PEEI +
Sbjct: 177 VTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHF 236
Query: 236 VAFLASDLGSYINGAMIPVDGGRLNSVF 263
V FL+S L S INGA + DGG + SVF
Sbjct: 237 VTFLSSPLSSAINGAALRADGGLVRSVF 264
>gb|AAA23739.1| (M84991) 3-ketoacyl-acyl carrier protein reductase [Escherichia
coli]
Length = 244
Score = 113 bits (280), Expect = 2e-24
Identities = 79/255 (30%), Positives = 125/255 (48%), Gaps = 16/255 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++ GK+A T +S+GIG +A LA G VI + +E + I + +
Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGGKVIGTATSENGA----QAISDYLGANGKGL 56
Query: 64 VADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
+ ++T +E +++++ GE DI + G + M M E+W + ++ L
Sbjct: 57 MLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFR 116
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L+KA++ AM +K GRII SV A + + G ++LA+E+ +GITV
Sbjct: 117 LSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITV 176
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I TD L+ D+ R G + +P GRLG +EI VAFLASD
Sbjct: 177 NVVAPGFIETDMTRALSDDQ--RAGILAQ---------VPAGRLGGAQEIANAVAFLASD 225
Query: 243 LGSYINGAMIPVDGG 257
+YI G + V+GG
Sbjct: 226 EAAYITGETLHVNGG 240
>gb|AAF51985.1| (AE003602) CG11005 gene product [Drosophila melanogaster]
Length = 1639
Score = 113 bits (280), Expect = 2e-24
Identities = 79/253 (31%), Positives = 119/253 (46%), Gaps = 7/253 (2%)
Query: 7 SGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVAD 66
S K+ T +S GIG A LAK G ++I+ RNEE LK + I + AD
Sbjct: 1387 SDKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQAD 1446
Query: 67 LTKMDDLERTV-KELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
+TK ++++ V L G D+ + G + G S+E ++ + + LT
Sbjct: 1447 MTKEAEVQQIVGATLAKHGRIDVLVNNAGILETGSIEATSLEQFDRLMNTNVRSLYQLTM 1506
Query: 126 ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
P + K G I+ +SV P + NV + A+ +A EL PKG+ VN +
Sbjct: 1507 LATPELV-KTKGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAV 1565
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG+I TD R + +T + L+ LGR G+ +E+ +AFLASD S
Sbjct: 1566 NPGVIVTD-----IHKRGGMDEETYAKFLEHCKITHALGRPGDVKEVAAAIAFLASDQAS 1620
Query: 246 YINGAMIPVDGGR 258
+ G +PVDGGR
Sbjct: 1621 FTTGISLPVDGGR 1633
>emb|CAB60468.1| (AL132856) probable oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 264
Score = 113 bits (280), Expect = 2e-24
Identities = 84/266 (31%), Positives = 135/266 (50%), Gaps = 9/266 (3%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE-SNVEV 60
+ +DL G+ A T SS+GIG +A LA+AGA V + R+ L + EK++ E +
Sbjct: 1 MNLDLGGRTALVTGSSQGIGAAIAAGLARAGATVGVNGRDAGRLAESVEKLRAEVPDGTF 60
Query: 61 HYIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ ADL + ER ++ L ++ DI + G +E+S +W ++ +
Sbjct: 61 VPVAADLGTEEGAERALEALPDV---DILVNNLGVFGAAPALEISDAEWRRYFEINVLAG 117
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+ LT+A +P M +G+GR++Y S + + V + A+ G+ R AKE G+
Sbjct: 118 VRLTRAHLPRMRDRGWGRVLYIASDSAVVIPSEMIHYGVSKTALLGVGRGFAKEAAGSGV 177
Query: 181 TVNGIMPGIIRT----DRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLV 236
TVN ++ G T D + QL DR + ++E+ L RL EPEEI LV
Sbjct: 178 TVNCVIAGPTHTEGVEDFVYQLV-DRDLPWDEAQRVFMREHRPQSLLQRLIEPEEIANLV 236
Query: 237 AFLASDLGSYINGAMIPVDGGRLNSV 262
+L+S L S GA + VDGG ++S+
Sbjct: 237 VYLSSPLASATTGAAVRVDGGYVDSI 262
>sp|Q9X248|FABG_THEMA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7431037|pir||H72219
3-oxoacyl-(acyl carrier protein) reductase - Thermotoga
maritima (strain MSB8)
>gi|4982301|gb|AAD36790.1|AE001811_10 (AE001811)
3-oxoacyl-(acyl carrier protein) reductase [Thermotoga
maritima]
Length = 246
Score = 113 bits (279), Expect = 3e-24
Identities = 79/255 (30%), Positives = 124/255 (47%), Gaps = 17/255 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNV--EVHYI 63
L GK+ T ++ GIG + A+ GA VI ++ENL +KE + +V
Sbjct: 3 LEGKVCLITGAASGIGKATTLLFAQEGATVIAGDISKENLDSL---VKEAEGLPGKVDPY 59
Query: 64 VADLTKMDDLERTV-KELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
V ++T D ++ V K ++ G D+ + G + + M EDW+ + + L
Sbjct: 60 VLNVTDRDQIKEVVEKVVQKYGRIDVLVNNAGITRDALLVRMKEEDWDAVINVNLKGVFN 119
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+T+ +VP M ++ G I+ +SV P + + G+ +T AKEL + I V
Sbjct: 120 VTQMVVPYMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGRNIRV 179
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I T +L + K E AL IPLGR G+PEE+ ++ FLASD
Sbjct: 180 NAVAPGFIETPMTEKLPE-------KARETALSR----IPLGRFGKPEEVAQVILFLASD 228
Query: 243 LGSYINGAMIPVDGG 257
SY+ G +I +DGG
Sbjct: 229 ESSYVTGQVIGIDGG 243
>sp|Q48436|BUDC_KLEPN ACETOIN(DIACETYL) REDUCTASE (ACETOIN DEHYDROGENASE) (AR)
>gi|1468939|dbj|BAA13085.1| (D86412) meso-2,3-butanediol
dehydrogenase (D-acetoin forming) [Klebsiella
pneumoniae]
Length = 256
Score = 112 bits (277), Expect = 5e-24
Identities = 75/251 (29%), Positives = 128/251 (50%), Gaps = 3/251 (1%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K+A T + +GIG +A L K G V I N+ K +I + V + D++
Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVA-VKVDVS 61
Query: 69 KMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
D + V++ K +G D+ + G ++ E ++ + + I+ +A
Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAA 121
Query: 128 VPAMERKGFG-RIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
V A +++G G +II + S A P +A+ + + A+ GL +T A++L P GITVNG
Sbjct: 122 VEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYC 181
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PGI++T ++ + ++ GK + E+AK I LGRL EPE++ V++LAS Y
Sbjct: 182 PGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSDY 241
Query: 247 INGAMIPVDGG 257
+ G + +DGG
Sbjct: 242 MTGQSLLIDGG 252
>gb|AAA65204.1| (L35560) daunorubicin-doxorubicin polyketide synthase [Streptomyces
peucetius] >gi|1093561|prf||2104259C doxorubicin
polyketide synthase [Streptomyces peucetius]
Length = 261
Score = 111 bits (276), Expect = 6e-24
Identities = 78/256 (30%), Positives = 127/256 (49%), Gaps = 4/256 (1%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
+ + ++A T + GIG V R LA+ G V + +R+E + +++ + S +EV
Sbjct: 3 EAADRVALVTGGTSGIGLAVVRKLAQDGTRVFLCARDESAITGTVKEL-QASGLEVDGAP 61
Query: 65 ADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+ D++R V+ +N G DI + G G E++ + W + V L A +
Sbjct: 62 CDVRSTADVDRLVQTARNRFGPIDIVVNNAGRGGGGVTAEITDDLWLDVVDTNLSGAFRV 121
Query: 124 TKALVP--AMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
T+A++ AM+ G+GRII S K+ + A + + + G + +A EL GIT
Sbjct: 122 TRAVLTGGAMQEHGWGRIISIASTGGKQGVALGAPYSASKSGLIGFTKAVALELAKTGIT 181
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG + T + Q A G T ++ L+++ IPLGR PEE+ +V +LAS
Sbjct: 182 VNAVCPGYVETPMAQGVRQRYAAFWGITEDDVLEKFQAKIPLGRYSMPEEVAGMVHYLAS 241
Query: 242 DLGSYINGAMIPVDGG 257
D I I V GG
Sbjct: 242 DSADSITAQAINVCGG 257
>gb|AAC78679.1| (AF098800) acetoin reductase [Klebsiella pneumoniae]
Length = 256
Score = 111 bits (275), Expect = 9e-24
Identities = 74/251 (29%), Positives = 127/251 (50%), Gaps = 3/251 (1%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K+A T + +GIG +A L K G V I N+ K +I + + D++
Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGG-RAMAVKVDVS 61
Query: 69 KMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
D + V++ K +G D+ + G ++ E ++ + + I+ +A
Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAA 121
Query: 128 VPAMERKGFG-RIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
V A +++G G +II + S A P +A+ + + A+ GL +T A++L P GITVNG
Sbjct: 122 VEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYC 181
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PGI++T ++ + ++ GK + E+AK I LGRL EPE++ V++LAS Y
Sbjct: 182 PGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSDY 241
Query: 247 INGAMIPVDGG 257
+ G + +DGG
Sbjct: 242 MTGQSLLIDGG 252
>pir||F82128 3-oxoacyl-(acyl-carrier-protein) reductase VC2021 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9656565|gb|AAF95169.1| (AE004276)
3-oxoacyl-(acyl-carrier-protein) reductase [Vibrio
cholerae]
Length = 248
Score = 111 bits (275), Expect = 9e-24
Identities = 78/255 (30%), Positives = 127/255 (49%), Gaps = 16/255 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++L GK+A T +S+GIG +A +LA+ GA VI + +E + + + + +
Sbjct: 5 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKG----M 60
Query: 64 VADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
++T + +E +K + + G DI + G + M M E+W + ++ L
Sbjct: 61 ALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFR 120
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L+KA++ M +K GRII SV A + + G +++A+E+ +G+TV
Sbjct: 121 LSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTV 180
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I TD M + D E +T A +P GRLG+P EI VAFLAS
Sbjct: 181 NTVAPGFIETD-MTKALND----EQRTATLA------QVPAGRLGDPREIASAVAFLASP 229
Query: 243 LGSYINGAMIPVDGG 257
+YI G + V+GG
Sbjct: 230 EAAYITGETLHVNGG 244
>sp|P50199|GNO_GLUOX GLUCONATE 5-DEHYDROGENASE (5-KETO-D-GLUCONATE 5-REDUCTASE)
>gi|2120837|pir||A57149 gluconate 5-dehydrogenase (EC
1.1.1.69) - Gluconobacter oxydans
>gi|563366|emb|CAA56322.1| (X80019) gluconate
oxidoreductase [Gluconobacter oxydans]
Length = 256
Score = 111 bits (275), Expect = 9e-24
Identities = 75/253 (29%), Positives = 126/253 (49%), Gaps = 11/253 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
LSG A T +S+GIG +A+ LA+ GA+V++ RN E+L A+ + E ++ V
Sbjct: 9 LSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEG-LKASTAVF 67
Query: 66 DLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+T D + V + +++G DI + G + E S +DW++ + + ++
Sbjct: 68 DVTDQDAVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAVFFVG 127
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
+A+ M +G G+I+ SV + P IA + A+ L + +A + G G+ +NG
Sbjct: 128 QAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGLQING 187
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
+ PG T+ +L D EE K P GR G+ EE+ FL+S
Sbjct: 188 LAPGYFATEMTERLVAD---------EEFTDWLCKRTPAGRWGQVEELVGAAVFLSSRAS 238
Query: 245 SYINGAMIPVDGG 257
S++NG ++ VDGG
Sbjct: 239 SFVNGQVLMVDGG 251
>sp|P25529|HDHA_ECOLI 7-ALPHA-HYDROXYSTEROID DEHYDROGENASE (7-ALPHA-HSDH)
>gi|95628|pir||A38527 7alpha-hydroxysteroid
dehydrogenase (EC 1.1.1.159) - Escherichia coli
>gi|1943533|pdb|1FMC|A Chain A, 7-Alpha-Hydroxysteroid
Dehydrogenase Complex With Nadh And 7-Oxo
Glycochenodeoxycholic Acid >gi|1943534|pdb|1FMC|B Chain
B, 7-Alpha-Hydroxysteroid Dehydrogenase Complex With
Nadh And 7-Oxo Glycochenodeoxycholic Acid
>gi|1827713|pdb|1AHI|A Chain A, 7 Alpha-Hydroxysteroid
Dehydrogenase Complexed With Nadh And 7-Oxo
Glycochenodeoxycholic Acid >gi|1827714|pdb|1AHI|B Chain
B, 7 Alpha-Hydroxysteroid Dehydrogenase Complexed With
Nadh And 7-Oxo Glycochenodeoxycholic Acid
>gi|1827715|pdb|1AHH|A Chain A, 7 Alpha-Hydroxysteroid
Dehydrogenase Complexed With Nad+ >gi|1827716|pdb|1AHH|B
Chain B, 7 Alpha-Hydroxysteroid Dehydrogenase Complexed
With Nad+ >gi|912437|dbj|BAA01384.1| (D10497)
7alpha-hydroxysteroid dehydrogenase [Escherichia coli]
>gi|1742673|dbj|BAA15370.1| (D90805) 7-a-hydroxysteroid
dehydrogenase (EC 1.1.1.159) (7-alpha-HSDH).
[Escherichia coli] >gi|1742681|dbj|BAA15377.1| (D90806)
7-a-hydroxysteroid dehydrogenase (EC 1.1.1.159)
(7-alpha-HSDH). [Escherichia coli]
>gi|1742713|dbj|BAA15407.1| (D90808) 7-a-hydroxysteroid
dehydrogenase (EC 1.1.1.159) (7-alpha-HSDH).
[Escherichia coli] >gi|1787905|gb|AAC74691.1| (AE000257)
NAD-dependent 7alpha-hydroxysteroid dehydrogenase,
dehydroxylation of bile acids [Escherichia coli K12]
Length = 255
Score = 111 bits (274), Expect = 1e-23
Identities = 76/253 (30%), Positives = 123/253 (48%), Gaps = 13/253 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK A T + GIG +A A AGA V++ N + ++I++ +
Sbjct: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG-QAFACRC 67
Query: 66 DLTKMDDLERTVK-ELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+T +L + +G+ DI + GG P F +M M D+ A +L ++ +L+
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
+ + P ME+ G G I+ TS+A + N+ + A + LVR +A +LG K I VNG
Sbjct: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
I PG I TD + + E Q+ + P+ RLG+P++I FL S
Sbjct: 187 IAPGAILTDAL----------KSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236
Query: 245 SYINGAMIPVDGG 257
S+++G ++ V GG
Sbjct: 237 SWVSGQILTVSGG 249
>pir||S54815 urdamycin polyketide ketoreductase (EC 1.1.1.-) - Streptomyces
fradiae >gi|809108|emb|CAA60572.1| (X87093) putative
ketoreductase [Streptomyces fradiae]
Length = 261
Score = 111 bits (274), Expect = 1e-23
Identities = 73/252 (28%), Positives = 122/252 (47%), Gaps = 4/252 (1%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K+A T ++ GIG V R+L + G V + +R E+++ +++ +E +EV D+
Sbjct: 7 KVAIVTGATSGIGLAVTRLLGRQGHRVFLCARTEDSVTSTVKQLLDEG-LEVDGAPCDVR 65
Query: 69 KMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
DD+ER V+ + G D+ + G G +++ E W + + L +T+ +
Sbjct: 66 SADDVERFVQRAVHRFGTIDVLVNNAGRSGGGVTADIADELWHDVIDTNLNSVFRMTREV 125
Query: 128 VPA--MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
+ M K GRII S A K+ + A + + + G + L EL P GITVN +
Sbjct: 126 LNTGGMRHKDRGRIINIASTAGKQGVVLGAPYSASKHGVVGFTKALGNELAPTGITVNAV 185
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG + T ++ A + + L+++ IPLGR PEE+ LV +LASD +
Sbjct: 186 CPGYVETPMAQRVRAGYAAAYDTSEDAILEKFQAKIPLGRYSTPEEVAGLVGYLASDTAA 245
Query: 246 YINGAMIPVDGG 257
I + V GG
Sbjct: 246 SITSQALNVCGG 257
>sp|P73574|FAG1_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE 1 (3-KETOACYL- ACYL
CARRIER PROTEIN REDUCTASE 1) >gi|7430983|pir||S77280
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) - Synechocystis sp. (strain PCC 6803)
>gi|1652694|dbj|BAA17614.1| (D90907)
3-oxoacyl-[acyl-carrier protein] reductase
[Synechocystis sp.]
Length = 247
Score = 111 bits (274), Expect = 1e-23
Identities = 80/257 (31%), Positives = 121/257 (46%), Gaps = 22/257 (8%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE---SNVEVHY 62
L+ ++A T +S+GIG A LA G V++ N A + + E + E
Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVV---NYAQSSTAADAVVAEIIANGGEAIA 60
Query: 63 IVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ A++ D++++ +K L D+ + G + + M +EDW+ + L L
Sbjct: 61 VQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVF 120
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
TKA+ M ++ GRII TSVA P A + + + G +T+AKEL +G+T
Sbjct: 121 LCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVT 180
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG I TD E E LQ IPL R G+PEE+ + FLA+
Sbjct: 181 VNAVAPGFIATD----------MTENLNAEPILQF----IPLARYGQPEEVAGTIRFLAT 226
Query: 242 D-LGSYINGAMIPVDGG 257
D +YI G VDGG
Sbjct: 227 DPAAAYITGQTFNVDGG 243
>gb|AAF67503.1|AF170880_10 (AF170880) NovJ [Streptomyces spheroides]
Length = 262
Score = 111 bits (274), Expect = 1e-23
Identities = 79/252 (31%), Positives = 121/252 (47%), Gaps = 11/252 (4%)
Query: 10 LAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTK 69
+A T + +GIG A LA G VI++ R E++ + I+ I D+
Sbjct: 18 VAMVTGAGRGIGAATAERLAAEGMAVIVVDRTEQDTRATVAAIRTAGG-RARGIGCDVAV 76
Query: 70 MDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKALV 128
+ V ++ G D+ G + + M ++W+ + + L + + A+
Sbjct: 77 AQAVTAAVATAVEEFGRIDVLVNCAGINRDRLLLTMGDQEWDTVLDVNLGGTMRCSFAVG 136
Query: 129 PAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKGITVNGIM 186
M R+G GRII +SVA + N +N + A+AG RTLA ELGP G+TVN I
Sbjct: 137 RHMRRQGHGRIINFSSVAARG---NAGQTNYATAKGAIAGFTRTLAAELGPHGVTVNAIA 193
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PG + T + +LA+ R G + + E AK +GR+G PEEI V F+A Y
Sbjct: 194 PGFVATPMVDELAE----RLGGDRDSVMSEAAKSSAVGRIGTPEEIAATVVFVARPESGY 249
Query: 247 INGAMIPVDGGR 258
+ G + VDGGR
Sbjct: 250 LTGETVHVDGGR 261
>sp|Q9X6U2|BDHA_ALCEU D-BETA-HYDROXYBUTYRATE DEHYDROGENASE (BDH) (3-HYDROXYBUTYRATE
DEHYDROGENASE) (3-HBDH)
>gi|4929323|gb|AAD33952.1|AF145230_1 (AF145230)
beta-hydroxybutyrate dehydrogenase [Ralstonia eutropha]
Length = 258
Score = 110 bits (272), Expect = 2e-23
Identities = 75/258 (29%), Positives = 129/258 (49%), Gaps = 11/258 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK A T S+ GIG G+A+ LA GA++I+ + + +A E + + V Y A
Sbjct: 2 LNGKTALVTGSTSGIGLGIAKALAAQGANIIVNGFGDADAAKA-EIAQAGQGIRVGYHGA 60
Query: 66 DLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D++K ++E ++ + + G DI + G + E W+ + + L A + T
Sbjct: 61 DMSKAAEIEDMMRYAQSDFGGADILVNNAGIQHVAAIEDFPPERWDAIIAINLTSAFHTT 120
Query: 125 KALVPAMERKGFGRIIYSTS----VAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+ +P M++K +GRII S VA + +A + + G + A E G+
Sbjct: 121 RLALPGMKQKDWGRIINVASTHGLVASAQKSAYVAAKH----GIVGFTKVTALETAQTGV 176
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYA-KPIPLGRLGEPEEIGYLVAFL 239
T N I PG + T + + + RA++EG VE+A +E + P G+ P+E+G L F
Sbjct: 177 TANAICPGWVLTPLVQKQVEARAQKEGIPVEQAKRELVLEKQPSGQFVTPDELGALAVFQ 236
Query: 240 ASDLGSYINGAMIPVDGG 257
+S+ + GA+ +DGG
Sbjct: 237 SSEAARQVRGAIWNMDGG 254
>gb|AAF89246.1|AF284419_2 (AF284419) 3-oxoacyl-(acyl carrier protein) reductase
[Sinorhizobium meliloti]
Length = 245
Score = 110 bits (272), Expect = 2e-23
Identities = 78/254 (30%), Positives = 123/254 (47%), Gaps = 16/254 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DLSG+ A T +S GIG +AR+L GA V + E L+ + E V
Sbjct: 3 DLSGRKALVTGASGGIGEEIARMLHAQGAVVGLHGTRVEKLETLANTLGER----VQIFP 58
Query: 65 ADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
A+L+ +++ ++ + ++G DI + G K G F+ MS EDW+ +++ L L
Sbjct: 59 ANLSDRAEVKALGEKAEADLGGVDILVNNAGITKDGLFVRMSDEDWDNVIEVNLTAVFRL 118
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
T+ L M R+ FGRI+ TSV P A + M G ++LA+E+ + +TVN
Sbjct: 119 TRELTHPMMRRRFGRIVNITSVVGVTGNPGQANYCASKAGMIGFSKSLAQEIATRNVTVN 178
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG I + GK ++ + IP+ R+G E+ VA+LAS+
Sbjct: 179 CVAPGFI-----------ESAMTGKLNDKQKEGIMSAIPMRRMGSGAEVASAVAYLASNE 227
Query: 244 GSYINGAMIPVDGG 257
Y+ G I V+GG
Sbjct: 228 AGYVTGQTIHVNGG 241
>pir||F83134 probable short-chain dehydrogenase PA4089 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950289|gb|AAG07476.1|AE004825_5 (AE004825) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 253
Score = 110 bits (272), Expect = 2e-23
Identities = 77/256 (30%), Positives = 119/256 (46%), Gaps = 16/256 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L ++A T + +GIG +A A GA V++ +R + E I+ +
Sbjct: 4 LENRVALVTGAGQGIGRAIAECFAAEGARVLLATRTASRGQAVLEAIRLGGGT-AELLAV 62
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
DL++ D R V L+ G+ DI + E+ E + + L LT
Sbjct: 63 DLSEYDAARRAVSATLERFGQLDILLHNAAAFPQCALAELDEGTLERTLAVNLKSCFRLT 122
Query: 125 KALVPAMERKGFGRIIYSTSVA-IKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+A +PA+ R GR++ ++SV + IP ++ + + G +R A EL GITVN
Sbjct: 123 QAALPALRRSVAGRVLVTSSVTGPRTAIPGLSHYAASKAGVNGFIRAAALELAGDGITVN 182
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
G+ PG++ T + L A A IPLGR+G+P +I + + FLASD
Sbjct: 183 GVEPGLVATPALGSLGDAAA-------------LAAHIPLGRVGQPLDIAHAMLFLASDE 229
Query: 244 GSYINGAMIPVDGGRL 259
SYI G + VDGG L
Sbjct: 230 ASYITGQTLVVDGGAL 245
>gb|AAG03071.1|AF293355_7 (AF293355) putative reductase [Streptomyces collinus]
Length = 249
Score = 109 bits (271), Expect = 3e-23
Identities = 82/258 (31%), Positives = 121/258 (46%), Gaps = 12/258 (4%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+++ L G+ T ++GIG G+ A+AGADV+ R E + +E+ + H
Sbjct: 1 MELALHGRKLLITGGTRGIGRGIVLAAARAGADVLTCYRQESEAVDSLTAALKETAGDHH 60
Query: 62 YIVADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
I AD+ + +R V E K+ G D + G F E+ ++W + L A
Sbjct: 61 VIRADVGDTAEADRLVGEAKDRFGRLDGVVNNAGVISHIPFGELPADEWSRILDTNLTAA 120
Query: 121 IYLTKALVPAMERKGFGRIIYST-SVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+ +P + G G + + S IP A + AM GL R+LAKELGPKG
Sbjct: 121 YRIIHQALPLL---GTGSSVVNIGSRGAAAGIPLRAHYTAAKAAMIGLTRSLAKELGPKG 177
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN + PG+I T+ + +RA T Y++ L RLG EE+ V FL
Sbjct: 178 IRVNVVAPGVIETEAFADMPAERAAGLRAT-------YSQKTALARLGTVEELAGPVLFL 230
Query: 240 ASDLGSYINGAMIPVDGG 257
SD +YI G + VDGG
Sbjct: 231 LSDAAAYITGETLNVDGG 248
>sp|P17611|NODG_AZOBR NODULATION PROTEIN G >gi|1070431|pir||DEKCNG acetoacetyl-CoA
reductase (EC 1.1.1.36) - Azospirillum brasilense
>gi|38686|emb|CAA46021.1| (X64772) ORF3 [Azospirillum
brasilense]
Length = 246
Score = 109 bits (270), Expect = 3e-23
Identities = 69/255 (27%), Positives = 130/255 (50%), Gaps = 16/255 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
+S K+A T + G+G + + LAK G I+ + N + A + ++ + + VA
Sbjct: 1 MSQKIALVTGAMGGLGTAICQALAKDGC--IVAANCLPNFEPAAAWLGQQEALGFKFYVA 58
Query: 66 --DLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D++ + + V +++ ++G DI + G + +F +M W+ + L
Sbjct: 59 EGDVSDFESCKAMVAKIEADLGPVDILVNNAGITRDKFFAKMDKAQWDAVIATNLSSLFN 118
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+T+ + P M +G+GRII +SV + + + + G + LA EL KG+TV
Sbjct: 119 VTQQVSPKMAERGWGRIINISSVNGVKGQAGQTNYSAAKAGVIGFTKALAAELATKGVTV 178
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG I TD ++ + +D + +A+ + +P+ RLG P+EIG V++LAS+
Sbjct: 179 NAIAPGYIGTDMVMAIRED--------IRQAITD---SVPMKRLGRPDEIGGAVSYLASE 227
Query: 243 LGSYINGAMIPVDGG 257
+ Y+ G+ + ++GG
Sbjct: 228 IAGYVTGSTLNINGG 242
>pir||E70881 probable fabG5 protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2624288|emb|CAA15562.1| (AL008967) fabG5
[Mycobacterium tuberculosis]
Length = 260
Score = 109 bits (270), Expect = 3e-23
Identities = 81/262 (30%), Positives = 128/262 (47%), Gaps = 20/262 (7%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEES-NVE 59
M +DL+G+ A T +S+GIG +A+ LA AGA V++ +R +E A ++ + + V
Sbjct: 1 MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVLTARRQEAADEAAAQVGDRALGVG 60
Query: 60 VHYIVADLTKMDDLERTVK-ELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLL 117
H + D + R V L+ G DI + G P G +E + + + L
Sbjct: 61 AHAVDEDAAR-----RCVDLTLERFGSVDILINNAGTNPAYGPLLEQDHARFAKIFDVNL 115
Query: 118 YPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGP 177
+ + T +V A + G ++ + S+ P + + N + A+ + + LA EL P
Sbjct: 116 WAPLMWTSLVVTAWMGEHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSP 175
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVA 237
+ I VN I PG++RT L +D E+ L A I LGR+GEP +I VA
Sbjct: 176 R-IRVNAICPGVVRTRLAEALWKDH--------EDPL---AATIALGRIGEPADIASAVA 223
Query: 238 FLASDLGSYINGAMIPVDGGRL 259
FL SD S+I G + +DGG L
Sbjct: 224 FLVSDAASWITGETMIIDGGLL 245
>gb|AAD32035.1|AF093787_3 (AF093787) CylG [Streptococcus agalactiae]
Length = 240
Score = 109 bits (270), Expect = 3e-23
Identities = 76/254 (29%), Positives = 130/254 (50%), Gaps = 18/254 (7%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI-VADL 67
K+A T ++GIG + + L K G VI + + + RA ++ E ++V+ ++D
Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQE--ELPKLDVYKCNISDA 59
Query: 68 TKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
+ L K + G D + G + G+F+ MS E W + + + + + ++KA+
Sbjct: 60 KAVQKL--VTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKAV 117
Query: 128 VPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
+ M+ K G++I +S + A + + A+ + +TLAKE GIT+N +
Sbjct: 118 LKIMKAKRIQGKVINISSTSGIAGQIGQANYSATKGAIISITKTLAKEFASDGITINCVS 177
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PG I TD +L +E L+E+ IPL R G+PEE+ +LV+FLAS+ +Y
Sbjct: 178 PGFIETDMTNELQN----------KEELKEHL--IPLKRFGQPEEVAWLVSFLASEKANY 225
Query: 247 INGAMIPVDGGRLN 260
I G I +DGG +N
Sbjct: 226 ITGKNIVIDGGMIN 239
>pir||H75616 oxidoreductase, short-chain dehydrogenase/reductase family -
Deinococcus radiodurans (strain R1)
>gi|6460474|gb|AAF12180.1|AE001862_6 (AE001862)
oxidoreductase, short-chain dehydrogenase/reductase
family [Deinococcus radiodurans]
Length = 258
Score = 109 bits (270), Expect = 3e-23
Identities = 80/260 (30%), Positives = 123/260 (46%), Gaps = 20/260 (7%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DLSGK+A T S+G+G +A L + GA V++ +R + L A+ + E V+ H
Sbjct: 8 DLSGKVALITGGSRGLGLQMAEALGEYGATVVLTARKQNELDEAKAHL-EGLGVKAHVYA 66
Query: 65 ADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
DL + ++ + ++ + +G DI + G E + W + + + + L
Sbjct: 67 NDLGNFESIDPLIAQIHQEVGPIDILINNAGATWGAPTAEHPFDAWMKVMNVNVNGTFLL 126
Query: 124 TKALV-PAMERKGFGRIIYSTSVA-----IKEPIPNIALSNVVRIAMAGLVRTLAKELGP 177
T++++ M G GRII SVA + +P +A N + A+ R LA EL P
Sbjct: 127 TQSVLNRCMLPAGKGRIINVASVAGLKGNSPQMMPTMAY-NTSKGAVVNFTRALASELAP 185
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVA 237
KGITVN I PG T K T+ A Q P+GRLG +++ L
Sbjct: 186 KGITVNSICPGYFPT-----------KMTRGTLAAAEQAIMSHTPMGRLGTDQDLKGLAV 234
Query: 238 FLASDLGSYINGAMIPVDGG 257
L+SD +Y+ G I VDGG
Sbjct: 235 LLSSDASAYMTGQNIAVDGG 254
>emb|CAC11337.1| (AL445063) probable glucose 1-dehydrogenase [Thermoplasma
acidophilum]
Length = 268
Score = 109 bits (269), Expect = 4e-23
Identities = 79/259 (30%), Positives = 130/259 (49%), Gaps = 13/259 (5%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAR-EKIKEESNVEV 60
+ I+L+GK+A T SS G+G +A+ +A+AGA V + R+ ++ A ++IK + +
Sbjct: 9 IAINLTGKIALVTGSSSGLGAAIAKYMARAGAKVAVHYRSGKDRADAIVDEIKNDGGFAM 68
Query: 61 HYIVADLTKMDDLERTVKELKN-IGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLY 118
+ D++K +D+++ E+ + +G DI + G K E +DWE+ +++ L
Sbjct: 69 AFY-GDVSKKEDVQKLFSEIDSKLGTVDILVNNAGIDGKRELVGEDDPDDWEKVIEVNLM 127
Query: 119 PAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
Y + V M+ K G II TSV P + + ++ + LA+EL
Sbjct: 128 GPYYCAREAVKRMKPKKSGVIINITSVHEYVPWSGYTAYSSAKAGLSMFTKALAQELSDY 187
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
I V I PG I+T ++ E+L++ I + RLGE ++IG F
Sbjct: 188 NIRVVAIAPGAIKTP---------INKDVWGNPESLKDLLNKIAMPRLGEVDDIGQAAVF 238
Query: 239 LASDLGSYINGAMIPVDGG 257
LASDL SYI G + VDGG
Sbjct: 239 LASDLASYITGTTLLVDGG 257
>dbj|BAA13547.1| (D88156) tropinone reductase-I [Hyoscyamus niger]
>gi|6136875|dbj|BAA85844.1| (AB026544) tropinone
reductase-I [Hyoscyamus niger]
Length = 274
Score = 108 bits (268), Expect = 6e-23
Identities = 76/259 (29%), Positives = 129/259 (49%), Gaps = 10/259 (3%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
++ L G A T SKGIG+ V LA GA V SRNE+ L++ + + E ++V
Sbjct: 16 IRWSLKGTTALVTGGSKGIGYAVVEELAGLGARVYTCSRNEKELQQCLDIWRNEG-LQVE 74
Query: 62 YIVADL---TKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLY 118
V DL ++ D L +TV +L N G+ +I + G + + ED++ +
Sbjct: 75 GSVCDLLLRSERDKLMQTVADLFN-GKLNILVNNAGVVIHKEAKDFTKEDYDIVLGTNFE 133
Query: 119 PAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
A +L + P ++ G +I+ +S+A +P+++L + + A+ + + LA E
Sbjct: 134 AAYHLCQLAYPFLKASQNGNVIFLSSIAGFSALPSVSLYSASKAAINQITKNLACEWAKD 193
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
I VN + PG+I T + + A ++ +E + + P+GR G+P E+ L+AF
Sbjct: 194 NIRVNSVAPGVILTPLI-----ETAIKKNPHQKEEIDNFIVKTPMGRAGKPNEVSALIAF 248
Query: 239 LASDLGSYINGAMIPVDGG 257
L SYI G +I DGG
Sbjct: 249 LCFPAASYITGQIIWADGG 267
>sp|P50164|TRN2_HYONI TROPINONE REDUCTASE-II (TR-II) >gi|425150|gb|AAB09776.1| (L20485)
tropinone reductase-II [Hyoscyamus niger]
>gi|6136877|dbj|BAA85845.1| (AB026545) tropinone
reductase-II [Hyoscyamus niger]
Length = 260
Score = 108 bits (267), Expect = 7e-23
Identities = 77/256 (30%), Positives = 123/256 (47%), Gaps = 11/256 (4%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEES-NVEVHYI 63
+L G A T S+GIG+G+ LA GA V SRN++ L + + + NVE
Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNVEAS-- 63
Query: 64 VADLTKMDDLERTVKELKNI--GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
V DL+ + E +K + N G+ +I + G + +MED+ + + A
Sbjct: 64 VCDLSSRSEREEFMKTVSNHFHGKLNILVNNAGIVIYKEAKDYTMEDYSHIMSINFEAAY 123
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
+L+ P ++ G +++ +S++ +P A+ + AM L R LA E I
Sbjct: 124 HLSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWAKDNIR 183
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VNG+ PG+I T + QD ++E L + L R+GEP+E+ +VAFL
Sbjct: 184 VNGVGPGVIATSMVEMTIQDPEQKEN------LDKLIDRCALRRMGEPKELAAVVAFLCF 237
Query: 242 DLGSYINGAMIPVDGG 257
SY+ G +I VDGG
Sbjct: 238 PAASYVTGQIIYVDGG 253
>gb|AAB36565.1| (AF126429) ketoreductase [Streptomyces venezuelae]
Length = 264
Score = 108 bits (267), Expect = 7e-23
Identities = 73/252 (28%), Positives = 122/252 (47%), Gaps = 4/252 (1%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
++A T ++ GIG VAR+LA V + +RN EN+ +++++E +EV D+
Sbjct: 10 RVALVTGATSGIGLAVARLLASQNHRVFLGARNAENVAATVKQLQDEG-LEVDGTTLDVR 68
Query: 69 KMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
+D++ V+ + G ++ + G G +++ E W + + L LT+
Sbjct: 69 SGEDVKAFVQAAVDRFGTVELLVNNAGRSGAGVTADIADELWNDVIDTNLNCVFRLTREA 128
Query: 128 VPA--MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
+ M K GRII S A K+ + A + + + G + L EL P GITVN +
Sbjct: 129 LTTGGMREKSRGRIINMASTAGKQGVVLGAPYSASKHGVVGFTKALGNELAPTGITVNAV 188
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG + T ++ Q A + + L+++ IPLGR PEE+ LV +LASD +
Sbjct: 189 CPGYVETPMAQRVRQGYAAAYETSEDAILEKFQSKIPLGRYSTPEEVAGLVGYLASDTAA 248
Query: 246 YINGAMIPVDGG 257
I + V GG
Sbjct: 249 SITSQALNVCGG 260
>sp|Q9Z8P2|FABG_CHLPN 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|7431036|pir||D72096
3-oxoacyl-(acyl-carrier protein) reductase CP0462
[imported] - Chlamydophila pneumoniae (strains CWL029
and AR39) >gi|4376571|gb|AAD18445.1| (AE001614) Oxoacyl
(Carrier Protein) Reductase [Chlamydophila pneumoniae
CWL029] >gi|7189384|gb|AAF38299.1| (AE002207)
3-oxoacyl-(acyl-carrier protein) reductase
[Chlamydophila pneumoniae AR39]
>gi|8978670|dbj|BAA98506.1| (AP002546) oxoacyl (carrier
protein) reductase [Chlamydophila pneumoniae J138]
Length = 248
Score = 108 bits (267), Expect = 7e-23
Identities = 81/260 (31%), Positives = 123/260 (47%), Gaps = 19/260 (7%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ I L GK T S+GIG G+ ++ + GADV I NEE + E + EV
Sbjct: 1 MDITLVGKKVIVTGGSRGIGLGIVKLFLENGADVEIWGLNEERGQAVIESLTGLGG-EVS 59
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ D++ ++ V++ L + DI + G + M MS +DW+ + L
Sbjct: 60 FARVDVSHNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDDWQSVISTNLTSL 119
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLV---RTLAKELGP 177
Y +++ M + G II S+ K I + +N A AG++ ++LAKE+
Sbjct: 120 YYTCSSVIRHMIKARSGSIINVASIVAK--IGSAGQTNYAA-AKAGIIAFTKSLAKEVAA 176
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVA 237
+ I VN + PG I TD M + D K E + K IPLGR G PE++ +
Sbjct: 177 RNIRVNCLAPGFIETD-MTSVLNDNLKAE----------WLKSIPLGRAGTPEDVARVAL 225
Query: 238 FLASDLGSYINGAMIPVDGG 257
FLAS L SY+ + VDGG
Sbjct: 226 FLASQLSSYMTAQTLVVDGG 245
>sp|Q9WYG0|Y325_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0325 >gi|7431047|pir||G72389
oxidoreductase, short chain dehydrogenase/reductase
family - Thermotoga maritima (strain MSB8)
>gi|4980826|gb|AAD35412.1|AE001714_3 (AE001714)
oxidoreductase, short chain dehydrogenase/reductase
family [Thermotoga maritima]
Length = 251
Score = 108 bits (267), Expect = 7e-23
Identities = 78/255 (30%), Positives = 128/255 (49%), Gaps = 9/255 (3%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++ GK+ T + GIG A + A+ GA V I +EE K E IK E +I
Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGG-EAAFI 59
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+ K D E+ VK+ ++ G DI + G G E S ED+++ + + +
Sbjct: 60 FGDVAK--DAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFL 117
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L+K V M+++G G I+ +S A IP + +V + A+ GL R+LA + GI V
Sbjct: 118 LSKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRV 177
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG +++ ++ + EE L++ IP+ RLG+ EEI + + F A D
Sbjct: 178 NAVCPGTTQSEGLMARV-----KASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAACD 232
Query: 243 LGSYINGAMIPVDGG 257
++ G++I +DGG
Sbjct: 233 EAGFMTGSIINIDGG 247
>gb|AAD42688.1|AF037323_1 (AF037323) D-beta-hydroxybutyrate dehydrogenase [Rhodobacter sp.
DSMZ 12077]
Length = 257
Score = 108 bits (266), Expect = 1e-22
Identities = 82/256 (32%), Positives = 111/256 (43%), Gaps = 5/256 (1%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRA-REKIKEESNVEVHY 62
+DL+GK A T S+ GIG G A LA+AGA+V+I S + + A EKI E V Y
Sbjct: 1 MDLNGKRAIVTGSNSGIGLGCAEELARAGAEVVINSFTDRDEDHALAEKIGREHGVSCRY 60
Query: 63 IVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
I AD M D E ++ G DI + G E + W + + L A +
Sbjct: 61 IAAD---MSDGEACRALIETAGGCDILVNNAGIQHVSSIEEFPVGKWNAILAINLSSAFH 117
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
T A +P M KG+GRI+ S P + + + G + A E KGIT
Sbjct: 118 TTAAALPGMRAKGWGRIVNIASAHGLTASPYKSAYVAAKHGVVGFTKVTALETAGKGITC 177
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQE-YAKPIPLGRLGEPEEIGYLVAFLAS 241
N I PG + T + D+ K E ++E P + +IG V FL S
Sbjct: 178 NAICPGYVLTPLVEAQIPDQMKAHDMDRETVIREVMLDRQPSRQFATTGQIGGTVVFLCS 237
Query: 242 DLGSYINGAMIPVDGG 257
I G I VDGG
Sbjct: 238 GAADQITGTTISVDGG 253
>emb|CAB52307.1| (AJ245634) tropinone reductase II [Solanum tuberosum]
Length = 261
Score = 108 bits (266), Expect = 1e-22
Identities = 74/255 (29%), Positives = 123/255 (48%), Gaps = 9/255 (3%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
+L G A T S+GIG+G+ LA GA V SRN++ L + + + +V V
Sbjct: 7 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNECLTQWRSKG-FKVEASV 65
Query: 65 ADLTKMDDLERTVKELKNI--GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
DL+ + E +K + N G+ +I + G + +MED+ + + A +
Sbjct: 66 CDLSSRSEREEFIKTVANHFDGKLNILVNNAGIVIYKEAKDYTMEDYSLIMSINFEAAYH 125
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L+ P ++ G +++ +S++ +P A+ + AM L R LA E I V
Sbjct: 126 LSVLAHPFLKASQRGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWAKDNIRV 185
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
NG+ PG+I + + QD+ ++E L + L R+GEP+E+ +VAFL
Sbjct: 186 NGVAPGVIASSMVEMTIQDQEQKEN------LDKLIDRCALHRMGEPKELAAVVAFLCFP 239
Query: 243 LGSYINGAMIPVDGG 257
SY+ G +I VDGG
Sbjct: 240 AASYVTGQIIYVDGG 254
>gb|AAF51984.1| (AE003602) CG12171 gene product [Drosophila melanogaster]
Length = 257
Score = 108 bits (266), Expect = 1e-22
Identities = 80/255 (31%), Positives = 120/255 (46%), Gaps = 15/255 (5%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K+ T +S GIG G + +LAK G + I+ RN + L E+I + AD+
Sbjct: 7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADIN 66
Query: 69 KMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
D++ V L G D+ + G + G S+E ++ + + LT +
Sbjct: 67 SESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLV 126
Query: 128 VPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMP 187
P + K G I+ +SV P + NV + A+ R +A EL PKG+ VN + P
Sbjct: 127 TPELI-KTKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNP 185
Query: 188 GIIRTDRMIQLAQDRAKREGKTVEEA---LQEYAKPI-PLGRLGEPEEIGYLVAFLASDL 243
G+I T+ +R G +EA E+AK LGR GE +E+ +AFLASD
Sbjct: 186 GVIITE---------LQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDE 236
Query: 244 GSYINGAMIPVDGGR 258
S+ G +PVDGGR
Sbjct: 237 ASFSTGISLPVDGGR 251
>gb|AAF74785.1|AF270650_1 (AF159243) 3-oxoacyl-(acyl carrier protein) reductase [Rhizobium
leguminosarum]
Length = 245
Score = 108 bits (266), Expect = 1e-22
Identities = 76/255 (29%), Positives = 125/255 (48%), Gaps = 16/255 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+DLSG+ A T +S GIG +AR+L + GA V + E L E + + V
Sbjct: 2 LDLSGRKALVTGASGGIGEEIARLLHRQGAIVGLHGTRVEKL----EALAADLGERVKIF 57
Query: 64 VADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
A+L+ D+++ ++ + ++ DI + G + G F+ MS EDW+ +++ L
Sbjct: 58 PANLSDRDEVKALGQKAEADLEGVDILVNNAGITRDGLFVRMSDEDWDSVIEVNLTATFR 117
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
LT+ L M R+ +GRII TSV P A + M G ++LA+E+ + +TV
Sbjct: 118 LTRELTHPMMRRRYGRIINITSVVGVTGNPGQANYCASKAGMIGFTKSLAQEIATRNVTV 177
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I + GK ++ + IP+ R+G E+ VA+LAS
Sbjct: 178 NCVAPGFI-----------ESAMTGKLNDKQKEAIMGAIPMKRMGTGGEVASAVAYLASS 226
Query: 243 LGSYINGAMIPVDGG 257
+Y+ G + V+GG
Sbjct: 227 EAAYMTGQTLHVNGG 241
>dbj|BAA98195.1| (AP002030) short chain alcohol dehydrogenase-like [Arabidopsis
thaliana]
Length = 264
Score = 108 bits (266), Expect = 1e-22
Identities = 80/254 (31%), Positives = 121/254 (47%), Gaps = 12/254 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK A T ++GIG V LAK GA V SRN+E L K V V V
Sbjct: 9 LAGKTALVTGGTRGIGRAVVEELAKFGAKVHTCSRNQEELNACLNDWKANGLV-VSGSVC 67
Query: 66 DLTKMDDLERTVKELKNI--GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D + D E+ ++E + G+ +I + G +E S E++ + + L A +L
Sbjct: 68 DASVRDQREKLIQEASSAFSGKLNILINNVGTNVRKPTVEYSSEEYAKIMSTNLESAFHL 127
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
++ P ++ G G I++ +SVA + + ++ + A+ L R LA E I N
Sbjct: 128 SQIAHPLLKASGVGSIVFISSVAGLVHLSSGSIYGATKGALNQLTRNLACEWASDNIRTN 187
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ P I+T + L + + E ++ PLGR+GEPEE+ LVAFL
Sbjct: 188 CVAPWYIKTSLVETLLEKK---------EFVEAVVSRTPLGRVGEPEEVSSLVAFLCLPA 238
Query: 244 GSYINGAMIPVDGG 257
SYI G +I VDGG
Sbjct: 239 SSYITGQVISVDGG 252
>pir||D55587 griseusin polyketide ketoreductase (EC 1.1.1.-) - Streptomyces
griseus >gi|488774|emb|CAA54861.1| (X77865)
ketoreductase [Streptomyces griseus]
Length = 261
Score = 107 bits (265), Expect = 1e-22
Identities = 74/256 (28%), Positives = 122/256 (46%), Gaps = 4/256 (1%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
D ++A T ++ GIG VAR+LA G V I +R+ EN+ +++ E ++V V
Sbjct: 3 DQDKRVAVVTGATSGIGLSVARLLASQGHRVFIGARSAENVAATVKELVAEG-LDVDGAV 61
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+ D+E ++ + G D+ + G G ++ E W + + L +
Sbjct: 62 VDVRSDADVEAWIQAAVDRFGTVDVVVNNAGRSGGGVTADIDPELWHDVIDTNLNSVFRV 121
Query: 124 TKALVPA--MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
T++ + + K GRII S A K+ + A + + + G + L EL P GIT
Sbjct: 122 TRSALNTGGLRSKSRGRIINIASTAGKQGVVLGAPYSASKHGVVGFTKALGNELAPTGIT 181
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG + T ++ Q A T + L+++ IPLGR P+E+ LV +LAS
Sbjct: 182 VNAVCPGYVETPMAQRVRQGYAAAYDATEDAILEKFQAKIPLGRYSTPDEVAGLVGYLAS 241
Query: 242 DLGSYINGAMIPVDGG 257
D + I + V GG
Sbjct: 242 DTAASITSQALNVCGG 257
>sp|P50842|KDUD_BACSU 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE (2-KETO-3-DEOXYGLUCONATE
OXIDOREDUCTASE) >gi|7430993|pir||D69648
2-keto-3-deoxygluconate oxidoreductase kduD - Bacillus
subtilis >gi|1146186|gb|AAB38476.1| (L47838)
2-keto-3-deoxygluconate oxidoreductase [Bacillus
subtilis] >gi|2634633|emb|CAB14131.1| (Z99115)
2-keto-3-deoxygluconate oxidoreductase [Bacillus
subtilis]
Length = 254
Score = 107 bits (265), Expect = 1e-22
Identities = 75/255 (29%), Positives = 121/255 (47%), Gaps = 11/255 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK A T GIG G+A+ LA AGAD+I S +L ++ +++E + + +
Sbjct: 10 LKGKTALVTGPGTGIGQGIAKALAGAGADIIGTSHTS-SLSETQQLVEQEGRIFTSFTL- 67
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
D++K + ++ + EL + DI + G + E+W+ + + L LT+
Sbjct: 68 DMSKPEAIKDSAAELFENRQIDILVNNAGIIHREKAEDFPEENWQHVLNVNLNSLFILTQ 127
Query: 126 ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
M ++G G+II S+ + + + A+AGL ++ A E GI VN I
Sbjct: 128 LAGRHMLKRGHGKIINIASLLSFQGGILVPAYTASKHAVAGLTKSFANEWAASGIQVNAI 187
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG I T + D + E + K IP GR G+ ++IG FLAS
Sbjct: 188 APGYISTANTKPIRDDEKRNE---------DILKRIPAGRWGQADDIGGTAVFLASRASD 238
Query: 246 YINGAMIPVDGGRLN 260
Y+NG ++ VDGG L+
Sbjct: 239 YVNGHILAVDGGWLS 253
>gb|AAD05259.1| (AF109909) 3-ketoacyl-CoA reductase PhaB [Bacillus megaterium]
Length = 247
Score = 107 bits (265), Expect = 1e-22
Identities = 76/254 (29%), Positives = 122/254 (47%), Gaps = 15/254 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+A T SKGIG + R LA G V + + + A K +++ E + A
Sbjct: 4 LQGKVAIVTGGSKGIGAAITRELASNGVKVAVNYNSSKESAEAIVKEIKDNGGEAIAVQA 63
Query: 66 DLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D++ +D + ++E K G+ DI + G + F ++ EDW++ + + L+ T
Sbjct: 64 DVSYVDQAKHLIEETKAAFGQLDILVNNAGITRDRSFKKLGEEDWKKVIDVNLHSVYNTT 123
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
A + + GR+I +S+ + + + M G ++LA EL G+TVN
Sbjct: 124 SAALTHLLESEGGRVINISSIIGQAGGFGQTNYSAAKAGMLGFTKSLALELAKTGVTVNA 183
Query: 185 IMPGIIRTDRMIQLAQD-RAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
I PG I T+ ++ + +D RAK K IP RLG EEI V +LA D
Sbjct: 184 ICPGFIETEMVMAIPEDVRAKIVAK------------IPTRRLGHAEEIARGVVYLAKD- 230
Query: 244 GSYINGAMIPVDGG 257
G+YI G + ++GG
Sbjct: 231 GAYITGQQLNINGG 244
>gb|AAG29782.1|AF235050_5 (AF235050) CumE [Streptomyces rishiriensis]
Length = 258
Score = 107 bits (265), Expect = 1e-22
Identities = 78/252 (30%), Positives = 122/252 (47%), Gaps = 11/252 (4%)
Query: 10 LAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTK 69
+A T + +GIG A LA G VI++ R E++ I+ + D++
Sbjct: 14 VAMVTGAGRGIGAATAERLAAEGMAVIVVDRVEQDTTATVSAIRAAGG-RASGLGCDVSV 72
Query: 70 MDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKALV 128
+ TV ++ G D+ G + + MS ++W+ + + L ++ + A+
Sbjct: 73 AQAVTATVASAVEEFGHLDVLVNCAGITQDRLLLTMSDQEWDRVLDVNLGGSMRCSFAVG 132
Query: 129 PAMERKGFGRIIYSTSVAIKEPIPNIALSN--VVRIAMAGLVRTLAKELGPKGITVNGIM 186
M R+G GRII +SVA + N +N + A+AG RTLA E GP G+TVN I
Sbjct: 133 RHMRRQGHGRIINFSSVAARG---NAGQTNYATAKGAIAGFTRTLAAEFGPHGVTVNSIA 189
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PG + T + +L + R G + L E A +GR+G PEEI +VAF+ Y
Sbjct: 190 PGFVATPMVAELTE----RLGVDRDTVLLEAAMSSAVGRIGTPEEIAAVVAFVTRPESGY 245
Query: 247 INGAMIPVDGGR 258
+ G I V+GGR
Sbjct: 246 LTGETIHVEGGR 257
>sp|P28643|FABG_CUPLA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE PRECURSOR
(3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|1084385|pir||S22450 3-oxoacyl-[acyl-carrier-protein]
reductase (EC 1.1.1.100) precursor, NADPH-dependent
[validated] - Cuphea lanceolata
>gi|18046|emb|CAA45866.1| (X64566)
3-oxoacyl-[acyl-carrier protein] reductase [Cuphea
lanceolata] >gi|228929|prf||1814446A beta ketoacyl-ACP
reductase [Cuphea lanceolata]
Length = 320
Score = 107 bits (264), Expect = 2e-22
Identities = 75/251 (29%), Positives = 120/251 (46%), Gaps = 15/251 (5%)
Query: 10 LAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVHYIVADLT 68
+ T +S+GIG +A L KAG V++ +R+ + + ++I+ + + D++
Sbjct: 79 VVIVTGASRGIGKAIALSLGKAGCKVLVNYARSSKEAEEVSKEIEAFGGQALTF-GGDVS 137
Query: 69 KMDDLERTVKELKNI-GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
K +D+E +K + G DI + G + G M M W+E + L L T+A
Sbjct: 138 KEEDVEAMIKTAVDAWGTVDILVNNAGITRDGLLMRMKKSQWQEVIDLNLTGVFLCTQAA 197
Query: 128 VPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMP 187
M +K GRII SV A + + + G +T+A+E + I VN + P
Sbjct: 198 AKIMMKKKKGRIINIASVVGLVGNAGQANYSAAKAGVIGFTKTVAREYASRNINVNAVAP 257
Query: 188 GIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA-SDLGSY 246
G I +D +L D K+ +T IPLGR G+PEE+ LV FLA + SY
Sbjct: 258 GFISSDMTSKLGDDINKKILET-----------IPLGRYGQPEEVAGLVEFLAINPASSY 306
Query: 247 INGAMIPVDGG 257
+ G + +DGG
Sbjct: 307 VTGQVFTIDGG 317
>gi|4503301 2,4-dienoyl CoA reductase 1 precursor; 4-enoyl-CoA reductase [Homo
sapiens] >gi|3913456|sp|Q16698|DECR_HUMAN
2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL PRECURSOR
(2,4-DIENOYL-COA REDUCTASE [NADPH]) (4-ENOYL-COA
REDUCTASE [NADPH]) >gi|1079476|pir||S53352
2,4-dienoyl-CoA reductase (NADPH) (EC 1.3.1.34)
precursor, mitochondrial - human
>gi|602703|gb|AAA67551.1| (L26050) 2,4-dienoyl-CoA
reductase [Homo sapiens] >gi|2673979|gb|AAB88724.1|
(U78302) 2,4-dienoyl-CoA reductase [Homo sapiens]
>gi|3080667|gb|AAC14671.1| (AC004612) 2,4-dienoyl-CoA
reductase precursor [Homo sapiens]
>gi|4126313|gb|AAD08723.1| (AF049895) 2,4-dienoyl-CoA
reductase [Homo sapiens]
Length = 335
Score = 106 bits (263), Expect = 2e-22
Identities = 81/255 (31%), Positives = 122/255 (47%), Gaps = 16/255 (6%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GK+AF T G+G G+ +L+ GA +I SR + LK E+I ++ +VH I D+
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDV 118
Query: 68 TKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT-- 124
D ++ TV EL K G P+I + G +S W+ ++L ++T
Sbjct: 119 RDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLE 178
Query: 125 --KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
K L+ A + F I T++ + + S + + + ++LA E G G+
Sbjct: 179 IGKQLIKAQKGAAFLSI---TTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG I+T + A R G +E + IP GRLG EE+ L AFL SD
Sbjct: 236 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGR----IPCGRLGTVEELANLAAFLCSD 287
Query: 243 LGSYINGAMIPVDGG 257
S+INGA+I DGG
Sbjct: 288 YASWINGAVIKFDGG 302
>pir||T36779 probable 3-oxacyl-(acyl-carrier-protein) reductase - Streptomyces
coelicolor >gi|5525067|emb|CAB50883.1| (AL096844)
probable 3-oxacyl-(acyl-carrier-protein) reductase
[Streptomyces coelicolor A3(2)]
Length = 234
Score = 106 bits (263), Expect = 2e-22
Identities = 80/245 (32%), Positives = 110/245 (44%), Gaps = 24/245 (9%)
Query: 14 TASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTKMDDL 73
T ++GIG +AR A AG V I R+ E E + V D+T + +
Sbjct: 8 TGGNRGIGLAIARAFADAGDKVAITYRSGE---------PPEGFLAVK---CDITDTEQV 55
Query: 74 ERTVKELKNIGEP-DIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKALVPAME 132
E+ KE++ P ++ + G K M MS ED+ V+ L + K AM
Sbjct: 56 EQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAML 115
Query: 133 RKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMPGIIRT 192
R GR++ +SV A + + G R+LA+ELG + IT N + PG + T
Sbjct: 116 RAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVDT 175
Query: 193 DRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSYINGAMI 252
D L +E +PLGR PEEI V FLASD SYI GA+I
Sbjct: 176 DMTKVLT-----------DEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVI 224
Query: 253 PVDGG 257
PVDGG
Sbjct: 225 PVDGG 229
>emb|CAB88214.1| (AJ400815) putative tropinone reductase [Solanum tuberosum]
Length = 264
Score = 106 bits (263), Expect = 2e-22
Identities = 71/254 (27%), Positives = 124/254 (47%), Gaps = 8/254 (3%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L G A T SKGIG+ + LA GA V SRNE L+ + I + ++V V
Sbjct: 10 LKGTTALVTGGSKGIGYAIVEELANFGARVYTCSRNENELQECLD-IWRKKGLKVEGSVC 68
Query: 66 DLTKMDDLERTVKELKNI--GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
DL + E+ +K ++++ G+ +I + G + + ED+ + A +L
Sbjct: 69 DLLSRTEREKLMKTIEDVFDGKLNILVNNAGVAIHKEAKDFTKEDYNIIMGTNFEAAYHL 128
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
++ P ++ G +I+ +S+A +P+++L + + A+ + + LA E I VN
Sbjct: 129 SQIAYPLLKASQNGNVIFVSSIAGFSALPSLSLYSASKGAINQMTKNLACEWAKDNIRVN 188
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ P +I T ++ + A ++ +E + PLGR G+PEE+ ++AFL
Sbjct: 189 SVAPAVILTPQI-----ETAIKKNPQQKEEIDSIVVKTPLGRAGKPEEVSAVIAFLCFPA 243
Query: 244 GSYINGAMIPVDGG 257
SYI G +I DGG
Sbjct: 244 ASYITGQIIWADGG 257
>gi|11427254 2,4-dienoyl CoA reductase 1, mitochondrial [Homo sapiens]
Length = 382
Score = 106 bits (263), Expect = 2e-22
Identities = 81/255 (31%), Positives = 122/255 (47%), Gaps = 16/255 (6%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GK+AF T G+G G+ +L+ GA +I SR + LK E+I ++ +VH I D+
Sbjct: 106 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDV 165
Query: 68 TKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT-- 124
D ++ TV EL K G P+I + G +S W+ ++L ++T
Sbjct: 166 RDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLE 225
Query: 125 --KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
K L+ A + F I T++ + + S + + + ++LA E G G+
Sbjct: 226 IGKQLIKAQKGAAFLSI---TTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 282
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG I+T + A R G +E + IP GRLG EE+ L AFL SD
Sbjct: 283 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGR----IPCGRLGTVEELANLAAFLCSD 334
Query: 243 LGSYINGAMIPVDGG 257
S+INGA+I DGG
Sbjct: 335 YASWINGAVIKFDGG 349
>sp|P55575|Y4MP_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Y4MP
>gi|2182533|gb|AAB91779.1| (AE000085) Y4mP [Rhizobium
sp. NGR234]
Length = 253
Score = 106 bits (261), Expect = 4e-22
Identities = 78/261 (29%), Positives = 126/261 (47%), Gaps = 19/261 (7%)
Query: 6 LSGKLAFTT--ASSKGIGFGVARVLAKAGADVIILSRNEENLKRAR---EKIKEESNVEV 60
L GK A + AS +GIG A + A GA V IL N + K A ++ +++ +
Sbjct: 3 LKGKTAVISGAASKRGIGRATAELFASHGARVAILDINADEAKAAAGDLPPVEHGAHIGL 62
Query: 61 HYIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
VAD V L G +I + G +P +++S DW+ V + +
Sbjct: 63 RCDVADRASCTSASDEV--LSAFGVANILINNAGITQPVKTLDISDADWQRIVAVNMTGV 120
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEP--IPNIALSNVVRIAMAGLVRTLAKELGPK 178
+ L++ +P M + G G I +SV+ + I + + + GL + +A+E GP
Sbjct: 121 LNLSQVFIPNMRQNGGGSIACMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMAREFGPD 180
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
I VN + PG+I+TD + D+ E + + K IPL RLG+ ++ + F
Sbjct: 181 SIRVNCVTPGLIQTD----ITGDKLSAEMRA------DIVKGIPLSRLGDARDVANIYLF 230
Query: 239 LASDLGSYINGAMIPVDGGRL 259
LASDL +Y+ GA+I V+GG L
Sbjct: 231 LASDLSAYVTGAVIDVNGGML 251
>emb|CAA74371.1| (Y14043) glucose-1-dehydrogenase [Staphylococcus xylosus]
Length = 263
Score = 106 bits (261), Expect = 4e-22
Identities = 79/262 (30%), Positives = 124/262 (47%), Gaps = 17/262 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIK--EESNVEVHY 62
DL GK+ T S GIG + K A V+I +E +L E IK E++ +
Sbjct: 4 DLEGKVVVITGGSSGIGKAMVEQFGKEKAKVVINYLSESSLDDVAESIKLIEDAGGQAIK 63
Query: 63 IVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ AD++K +D+ +K + G DI + G KP EM +E+W++ + + L A
Sbjct: 64 VHADVSKEEDVNNLIKAAVDTFGTLDILINNAGFEKPIPTHEMPLEEWQKVIDINLTGAF 123
Query: 122 YLTKALVPAM---ERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
+KA V ++KG I+ ++SV + P PN + + ++ T++ E
Sbjct: 124 IGSKAAVNQFLKEDKKGI--ILNTSSVHDRIPWPNYVNYAASKGGLKLMMETMSMEYAQH 181
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
GI +N I PG I T+ RE + E E + IP +GE +++ + F
Sbjct: 182 GIRINNISPGAIVTEHT---------REKFSDPETRAETLEMIPAKEIGEADQVANVARF 232
Query: 239 LASDLGSYINGAMIPVDGGRLN 260
L SDL YI+G I VDGG N
Sbjct: 233 LCSDLADYIHGTTIYVDGGMTN 254
>emb|CAB61800.1| (AL133236) putative dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 251
Score = 106 bits (261), Expect = 4e-22
Identities = 70/257 (27%), Positives = 125/257 (48%), Gaps = 15/257 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRN--EENLKRAREKIKEESNVEVHY 62
DL+G+ A T +G+G G++R L AGADV++LSR+ ++ L+R + V +
Sbjct: 6 DLTGRTAVVTGGGRGLGLGISRALLNAGADVVVLSRSALDDRLRRTAADLGR----SVSH 61
Query: 63 IVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
+ DL + + E+ + DI + G + ++ W+ + + L +
Sbjct: 62 VGVDLRDREGVAAAGAEVLAGHQVDILVNNAGAQIRHPAEDFPLDAWDAVLDVNLRSVVQ 121
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L + M ++G G+II S+ + +A + A+A L + L E +G+ V
Sbjct: 122 LCQIFGRPMIQRGEGKIINLASLLSFQGGFTVAAYAASKGAVAQLTKALCNEWAGRGVNV 181
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG + T+ L +D + L++ + IP GR G P+++G + FLAS
Sbjct: 182 NAIAPGYMATEMNTALLEDPVR---------LEQLSVRIPAGRWGGPDDVGDVAVFLASR 232
Query: 243 LGSYINGAMIPVDGGRL 259
+Y++G ++ VDGG L
Sbjct: 233 AAAYVHGQVLAVDGGWL 249
>gb|AAK42782.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-8) [Sulfolobus
solfataricus]
Length = 252
Score = 105 bits (260), Expect = 5e-22
Identities = 74/263 (28%), Positives = 130/263 (49%), Gaps = 26/263 (9%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
M+K+DLSGK+ T + GIG A + +K GA+V ++ R E N + +
Sbjct: 1 MIKLDLSGKVCLITGGTSGIGLKTAELFSKLGANVYVIGRREANFL----------SKNI 50
Query: 61 HYIVADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
++ DLT+ +D+ ++ KN+G + + +++ +++W+E + L L
Sbjct: 51 YFKKVDLTRREDVLSFIEWYEKNVGTIHVLINNASQNSRYSVLDIPIKEWDEMISLNLTA 110
Query: 120 AIYLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
L++ M ++G G+II +++ K P+ + + + R+LA +LG
Sbjct: 111 PFLLSRMAAKLMIKRGIKGKIINISAIQSKFPLERSFAYVTTKGGLISMGRSLAVDLGKY 170
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
GI V ++PG I + + +L + A + LGR+G EI +L+AF
Sbjct: 171 GIQVITVLPGPIYS-------------KDDEPPASLDKRAATL-LGRMGRMIEISHLLAF 216
Query: 239 LASDLGSYINGAMIPVDGGRLNS 261
LASDL S+I G I +DGGR+ S
Sbjct: 217 LASDLNSFITGTEIIIDGGRIIS 239
>sp|P39640|YWFD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PTA-ROCC INTERGENIC REGION
>gi|629089|pir||S39737 glucose 1-dehydrogenase homolog
ywfD - Bacillus subtilis >gi|414006|emb|CAA51638.1|
(X73124) ipa-82d [Bacillus subtilis]
>gi|2636308|emb|CAB15799.1| (Z99123) alternate gene
name: ipa-82d~similar to glucose 1-dehydrogenase
[Bacillus subtilis]
Length = 255
Score = 105 bits (260), Expect = 5e-22
Identities = 74/255 (29%), Positives = 123/255 (48%), Gaps = 7/255 (2%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++L+ K T + GIG+ + A+V++ +E + +++E+N +H++
Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEA---QGEAMVRKENNDRLHFV 59
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+T + V+ + G D+ + G EM + DW + +++ L
Sbjct: 60 QTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFL 119
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
++K + M G G II + SV P+I N + + L +++A + I V
Sbjct: 120 MSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRV 179
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PGII D + EG T+EE +E AK PL RLG+PEEI ++ FLASD
Sbjct: 180 NCVCPGII--DTPLNEKSFLENNEG-TLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASD 236
Query: 243 LGSYINGAMIPVDGG 257
L SY+ G+ I DGG
Sbjct: 237 LSSYMTGSAITADGG 251
>sp|P57432|FABG_BUCAI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|10039021|dbj|BAB13055.1|
(AP001119) 3-oxoacyl-[acyl-carrier protein] reductase
[Buchnera sp. APS]
Length = 244
Score = 105 bits (260), Expect = 5e-22
Identities = 73/255 (28%), Positives = 125/255 (48%), Gaps = 16/255 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++++ + AF T +++GIG +A+ L K G VI S E+ +KR + ++
Sbjct: 1 MNINRQTAFITGANQGIGKAIAKKLIKKGIQVIGTSTTEDGVKRINDYLEGNG----FGF 56
Query: 64 VADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
V +L +D + ++E+ K DI + G + + M +W++ +K L +
Sbjct: 57 VLNLKNIDSITEKIQEIYKKKHSIDILINNAGIKEDNLLVNMKSTEWDDVIKTNLSSVFH 116
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L K+++ +M +K GRII SV + + + G ++LA E+ KGITV
Sbjct: 117 LVKSVIRSMIKKRQGRIITIGSVIAYTGNKGQVNYSASKSGLIGFHKSLALEVASKGITV 176
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG+I+T+ +L + Q+Y IP+ R G+ EE+ V FLAS
Sbjct: 177 NIVSPGLIKTNFTEKLNSIQ-----------YQKYLSNIPMKRFGQKEEVADAVIFLASK 225
Query: 243 LGSYINGAMIPVDGG 257
SYI G + V+GG
Sbjct: 226 KASYITGHTLHVNGG 240
>pir||S11021 2,4-dienoyl-CoA reductase (NADPH) (EC 1.3.1.34) - rat
Length = 335
Score = 105 bits (259), Expect = 6e-22
Identities = 79/255 (30%), Positives = 117/255 (44%), Gaps = 16/255 (6%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GK+AF T G+G + L+ GA +I SRN + LK E+I ++ +V+ I D+
Sbjct: 59 GKVAFITGGGTGLGKAMTTFLSSLGAQCVIASRNIDVLKATAEEITSKTGNKVYAIRCDV 118
Query: 68 TKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT-- 124
D + TV EL K G PD+ + G +S W+ ++L Y+T
Sbjct: 119 RDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLSPNGWKTITDIVLNGTAYVTIE 178
Query: 125 --KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
K L+ A + F I T++ + + S+ + + + ++LA E G G+
Sbjct: 179 IGKQLIKAQKGAAFLAI---TTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRF 235
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG I+T K E +E IP GRLG EE+ L FL SD
Sbjct: 236 NIIQPGPIKTKGAFSRLDPTGKFEKDMIER--------IPCGRLGTVEELANLATFLCSD 287
Query: 243 LGSYINGAMIPVDGG 257
S+INGA+I DGG
Sbjct: 288 YASWINGAVIRFDGG 302
>emb|CAB95803.1| (AL359949) putative short chain oxidoreductase [Streptomyces
coelicolor A3(2)]
Length = 253
Score = 105 bits (259), Expect = 6e-22
Identities = 70/253 (27%), Positives = 121/253 (47%), Gaps = 7/253 (2%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
++A T +++GIG A LA G V ++ +E K EKI + + D++
Sbjct: 7 RVAVVTGAARGIGAATALRLAAEGRAVAVIDLDEAACKDTVEKITAAGGKAIA-VGCDVS 65
Query: 69 KMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
+E V + + +G P I + G + +MS+ DW+ + + L A +TKA
Sbjct: 66 DEAQVEAAVARIAEELGAPTILVNNAGVLRDNLLFKMSVSDWDTVMNVHLRGAFLMTKAC 125
Query: 128 VPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMP 187
M FGR++ +S + + S + + G +TLAKELG G+T N + P
Sbjct: 126 QKHMVDAKFGRVVNLSSSSALGNRGQVNYS-AAKAGLQGFTKTLAKELGKFGVTANAVAP 184
Query: 188 GIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSYI 247
G I T+ + + A R G ++ A IP+ R+GEP++I +AF + ++
Sbjct: 185 GFIATE----MTKATADRVGMGFDDFKAAAATQIPVARVGEPDDIANAIAFFTGEAAGFV 240
Query: 248 NGAMIPVDGGRLN 260
+G ++ V GG L+
Sbjct: 241 SGQVLYVAGGPLD 253
>pir||E82748 tropinone reductase XF0913 [imported] - Xylella fastidiosa (strain
9a5c) >gi|9105832|gb|AAF83723.1|AE003930_13 (AE003930)
tropinone reductase [Xylella fastidiosa]
Length = 261
Score = 105 bits (259), Expect = 6e-22
Identities = 79/258 (30%), Positives = 123/258 (47%), Gaps = 19/258 (7%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE-SNVEVHYIV 64
L G+ A T +S GIG VAR L GADV++++RN + L R R+++ EE E+H +
Sbjct: 11 LDGRTALITGASTGIGLAVARELLGLGADVLLVARNADLLGRVRDELAEEFPERELHGLA 70
Query: 65 ADLTKMDDLERT-----VKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
AD+ DD++R V++ N + + GG +E + ++W E ++ L+
Sbjct: 71 ADVA--DDVDRRAILDWVEDCSN--GLHVLINNAGGNVTRAALEYTEDEWREIFEINLFS 126
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
A L + P + I+ SV+ + + + + A+ + R LA E G
Sbjct: 127 AFELCRYTQPLLACHASTAIVNIGSVSGLTHVRSGVPYGMSKAALHQMTRNLAVEWAEDG 186
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN + P IRT R + D E + + P+ R+GEPEE+ VAFL
Sbjct: 187 IRVNAVAPWYIRTRRTSEPLSDVYYYE---------QVIERTPMRRIGEPEEVAAAVAFL 237
Query: 240 ASDLGSYINGAMIPVDGG 257
SY+ G I VDGG
Sbjct: 238 CLPASSYVTGECIAVDGG 255
>sp|P50162|TRN1_DATST TROPINONE REDUCTASE-I (TR-I) (TROPINE DEHYDROGENASE)
>gi|539026|pir||A48674 tropinone reductase (EC
1.1.1.236) I - jimsonweed >gi|4140004|pdb|1AE1|B Chain
B, Tropinone Reductase-I Complex With Nadp
>gi|4140003|pdb|1AE1|A Chain A, Tropinone Reductase-I
Complex With Nadp >gi|424160|gb|AAA33281.1| (L20473)
tropinone reductase-I [Datura stramonium]
Length = 273
Score = 104 bits (258), Expect = 8e-22
Identities = 75/255 (29%), Positives = 125/255 (48%), Gaps = 10/255 (3%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L G A T SKGIG+ + LA GA V SRNE+ L E I E + V V
Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLE-IWREKGLNVEGSVC 77
Query: 66 DL---TKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
DL T+ D L +TV + + G+ +I + G + + +D+ + A +
Sbjct: 78 DLLSRTERDKLMQTVAHVFD-GKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYH 136
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L++ P ++ G +I+ +S+A +P+++L + + A+ + ++LA E I V
Sbjct: 137 LSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRV 196
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG+I T + + A ++ +E + + P+GR G+P+E+ L+AFL
Sbjct: 197 NSVAPGVILTPLV-----ETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFP 251
Query: 243 LGSYINGAMIPVDGG 257
SYI G +I DGG
Sbjct: 252 AASYITGQIIWADGG 266
>emb|CAB51900.1| (Y19033) 1,3,6,8-tetrahydroxynaphthalene reductase [Aspergillus
fumigatus] >gi|6090729|gb|AAF03314.1|AF099736_1
(AF099736) 1,3,6,8-tetrahydroxynaphthalene reductase
[Aspergillus fumigatus]
Length = 273
Score = 104 bits (258), Expect = 8e-22
Identities = 83/268 (30%), Positives = 133/268 (48%), Gaps = 16/268 (5%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNV--EVH 61
+ LSGK+A T +GIG G+A LA+ GA V I + K A+E ++ + +
Sbjct: 8 LPLSGKVALVTGGGRGIGAGIALELARRGASVAI--NYGHSAKSAQEVVEAIQAIGRQAV 65
Query: 62 YIVADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
I ADLT + ++E ++E+ ++ G DI ++G K E ++ED+ E L
Sbjct: 66 AIQADLTCVPNIESLIQEVVRHFGRLDIVVSNSGMEKFKPLEETTLEDFNEVFNLNTRAQ 125
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+++ + ++ G R+I +S+A +P AL + A+ G R LA + G KG
Sbjct: 126 MFVARYAYDHIQPGG--RVILMSSIAAGLGVPGHALYAGSKAAIEGFTRCLAADFGRKGC 183
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAK--REGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
TVN I P +++D + A A + ++EE A PL R G PE+IG +V+F
Sbjct: 184 TVNAIAPAGVKSDMWRENAWRYAPGCDKSSSLEEIETALASGSPLKRCGVPEDIGKVVSF 243
Query: 239 LASDLGSYINGAMI-------PVDGGRL 259
LAS ++NG P+ GG L
Sbjct: 244 LASPDAEWVNGEFFSPPPCKGPLPGGDL 271
>dbj|BAB05886.1| (AP001514) 2-deoxy-D-gluconate 3-dehydrogenase [Bacillus
halodurans]
Length = 250
Score = 104 bits (258), Expect = 8e-22
Identities = 78/262 (29%), Positives = 124/262 (46%), Gaps = 13/262 (4%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
M L GK+A T +S+G+G G+A LA+AGADVI ++ R++I E
Sbjct: 1 MQLFSLEGKIALVTGASRGLGQGMAVGLAEAGADVI--GAGISDMSETRQQI-ESLGRTF 57
Query: 61 HYIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
+ + ADL + ++ + + ++ G DI + G + + +DW + + + L
Sbjct: 58 YELKADLFEEGAGKQLIADAIEKAGRIDILVNNAGIIRRNEAEAFTDKDWNDVINVNLNA 117
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+ + M GFGRII S+ + + + A+AGL ++LA E KG
Sbjct: 118 VFQMCREAGNHMIENGFGRIINIASMLSFQGGLRVPAYTASKHAIAGLTKSLANEWSKKG 177
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
+ VN I PG + TD L D + T IP G G P ++ V FL
Sbjct: 178 VNVNAIAPGYMVTDNTAALRADEVRNAYITSR---------IPKGEWGTPADLKGPVVFL 228
Query: 240 ASDLGSYINGAMIPVDGGRLNS 261
AS+ SY+NG ++ VDGG ++S
Sbjct: 229 ASEASSYVNGHILCVDGGWMSS 250
>sp|P50161|VER1_ASPPA VERSICOLORIN REDUCTASE (VER-1) >gi|1592833|gb|AAB42156.1| (M91369)
ketoreductase [Aspergillus parasiticus]
Length = 262
Score = 104 bits (257), Expect = 1e-21
Identities = 72/257 (28%), Positives = 132/257 (51%), Gaps = 9/257 (3%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+A T + +GIG +A L + GA V++ N + + A EK+ E+ +A
Sbjct: 7 LDGKVALVTGAGRGIGAAIAVALGERGAKVVV---NYAHSREAAEKVVEQIKANGTDAIA 63
Query: 66 DLTKMDDLERTVK----ELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ D E T K +++ G DI + G G+ +++ E+++ ++
Sbjct: 64 IQADVGDPEATAKLMAETVRHFGYLDIVSSNAGIVSFGHLKDVTPEEFDRVFRVNTRGQF 123
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ + M R+G I+ S++ A + +P A+ + + A+ VR +A + G K IT
Sbjct: 124 FVAREAYRHM-REGGRIILTSSNTACVKGVPKHAVYSGSKGAIDTFVRCMAIDCGDKKIT 182
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPI-PLGRLGEPEEIGYLVAFLA 240
VN + PG I+TD + ++++ +E + E A + PL R+G P ++ +V+FLA
Sbjct: 183 VNAVAPGAIKTDMFLAVSREYIPNGETFTDEQVDECAAWLSPLNRVGLPVDVARVVSFLA 242
Query: 241 SDLGSYINGAMIPVDGG 257
SD +++G +I VDGG
Sbjct: 243 SDTAEWVSGKIIGVDGG 259
>gb|AAC48769.1| (U71200) acetoin reductase [Bos taurus]
Length = 257
Score = 104 bits (257), Expect = 1e-21
Identities = 74/254 (29%), Positives = 124/254 (48%), Gaps = 3/254 (1%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
++ K+A T ++GIG + L+ G V + NE K I++ + +
Sbjct: 1 MTKKVAMVTGGAQGIGEAIVXXLSADGFAVAVADLNEAKSKXVATDIEKNGGTAIA-VKL 59
Query: 66 DLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D++ + VKE+ + +G D+ + G ++ E +++ + + I+
Sbjct: 60 DVSDREGFFAAVKEVAEKLGGFDVLVNNAGLGPTTPIDTITPELFDKVYHINVAGDIWGI 119
Query: 125 KALVPAMERKGFG-RIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+A V ++ G G +II +TS A PN++L + + A+ L A++L + ITVN
Sbjct: 120 QAAVEQFKKNGNGGKIINATSQAGVVGNPNLSLYSSTKFAVRCLTPVAARDLAEQNITVN 179
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
PGI++T +A + K GK E +Q +AK I L RL EPE++ VAFLA
Sbjct: 180 AYAPGIVKTPXXFDIAHEVGKNAGKDDEWGMQTFAKDIALKRLSEPEDVAAAVAFLAGPD 239
Query: 244 GSYINGAMIPVDGG 257
+YI G I VDGG
Sbjct: 240 SNYITGQTIEVDGG 253
>pir||F75557 oxidoreductase, short-chain dehydrogenase/reductase family -
Deinococcus radiodurans (strain R1)
>gi|6457780|gb|AAF09705.1|AE001874_2 (AE001874)
oxidoreductase, short-chain dehydrogenase/reductase
family [Deinococcus radiodurans]
Length = 340
Score = 104 bits (257), Expect = 1e-21
Identities = 79/255 (30%), Positives = 117/255 (44%), Gaps = 15/255 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK A T GI G+A+ A G V IL RN E + A + I + + + A
Sbjct: 77 LAGKHALITGGGSGINLGIAQSFAAHGCAVTILGRNLEKAQNAAQGIVDAGGRAMG-VSA 135
Query: 66 DLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+ LE V G+ DI G P +S ++ V + L
Sbjct: 136 DVRDFAALEAAVAAATAEFGDFDIVLAGAAGNFPAPVDGISPNGFKTVVDIDLLGTYNTI 195
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
KA P ++ G G I+ ++ + P+P A + + L +TLA E G +G+ VN
Sbjct: 196 KAAAPRLKVPG-GNILSISAYGV--PVPMQAHVVAAKAGVDALTQTLAVEWGLRGVRVNA 252
Query: 185 IMPGIIR-TDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
I+PG I T+ M +LA D R + + +PLGR G P++I FL SD
Sbjct: 253 IIPGPIDGTEGMARLAPDEKSRSA---------FTRTVPLGRFGVPQDIANAALFLVSDA 303
Query: 244 GSYINGAMIPVDGGR 258
SY+ G ++PVDGG+
Sbjct: 304 ASYVTGVILPVDGGQ 318
>emb|CAB59826.1| (AJ012388) diacetyl(acetoin) reductase [Lactococcus lactis]
Length = 256
Score = 104 bits (256), Expect = 1e-21
Identities = 73/251 (29%), Positives = 120/251 (47%), Gaps = 1/251 (0%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GKLA T S +GIG G+ LAK G V + N + K + + ++ Y++
Sbjct: 2 GKLAIVTGSGQGIGEGIVYRLAKDGFAVAVADINPQTAKNVAKTLIDKGFEAKAYVLDVA 61
Query: 68 TKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
+ + + + + GE +F + G ++ E E + + + +A
Sbjct: 62 NRSAVFQLIEQAVSDFGELAVFVNNAGVAFIDSIIDSDSERVERLFDVNIKGTYWGIQAA 121
Query: 128 VPAMERKGFG-RIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
+++G G RII + S+A E + + + A+ GL ++ AKEL ITVN
Sbjct: 122 ATQFKKQGHGGRIINAASLASVEGSALQSAYSASKFAIRGLTQSAAKELAKDYITVNAYN 181
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PGI+RT ++ + A+ +G ++E+ Q I LGR G PE++ +VA+ ASD Y
Sbjct: 182 PGIVRTAMRDEIDKKTAQIKGISIEQQQQNCLNEIYLGREGRPEDVAEVVAWFASDAAEY 241
Query: 247 INGAMIPVDGG 257
I G I VDGG
Sbjct: 242 ITGQSILVDGG 252
>gi|10047132 oxidoreductase UCPA [Homo sapiens]
>gi|8895083|gb|AAF80754.1|AF164790_1 (AF164790)
oxidoreductase UCPA [Homo sapiens]
Length = 245
Score = 104 bits (256), Expect = 1e-21
Identities = 72/253 (28%), Positives = 126/253 (49%), Gaps = 15/253 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+ TA+++GIG A A+ GA VI NE L +++++ ++ V
Sbjct: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKYPGIQTR--VL 57
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
D+TK +++ E++ + D+ F G G ++ +DW+ ++ L + + K
Sbjct: 58 DVTKKKQIDQFANEVERL---DVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 126 ALVPAMERKGFGRIIYSTSVAIK-EPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
A +P M + G II +SVA + + N + + + A+ GL +++A + +GI N
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
+ PG + T + Q+R + G EEA ++ K GR EEI L +LASD
Sbjct: 175 VCPGTVDTPSL----QERIQARGNP-EEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229
Query: 245 SYINGAMIPVDGG 257
+Y+ G + +DGG
Sbjct: 230 AYVTGNPVIIDGG 242
>pir||B70569 hypothetical protein Rv3485c - Mycobacterium tuberculosis (strain
H37RV) >gi|2104408|emb|CAB08708.1| (Z95390) hypothetical
protein Rv3485c [Mycobacterium tuberculosis]
Length = 314
Score = 103 bits (255), Expect = 2e-21
Identities = 75/260 (28%), Positives = 116/260 (43%), Gaps = 11/260 (4%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+++ + T GIG GVA L AGA V+I+ RN + L A + I+ +
Sbjct: 39 VQLSFQDRTYLVTGGGSGIGKGVAAGLVAAGAAVMIVGRNPDKLAAAVKDIEALKTGAIG 98
Query: 62 YIVADLTKMDDLERTVKELKNI-GEPDIFFFSTGGPKP-GYFMEMSMEDWEEAVKLLLYP 119
Y AD+T + R V G GG + G ++ + W V L +
Sbjct: 99 YEPADITDEEQTLRVVDAATAWHGRLHGVVHCAGGSQTIGPITQIDSQAWRRTVDLNVNG 158
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+Y+ K + R G G + +S+A V + A+ +++ A ELGP
Sbjct: 159 TMYVLKHAARELVRGGGGSFVGISSIAASNTHRWFGAYGVTKSAVDHMMKLAADELGPSW 218
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
+ VN I PG+IRTD ++ + + E +Y PL R+GE E++ L FL
Sbjct: 219 VRVNSIRPGLIRTDLVVPVTES---------PELSADYRVCTPLPRVGEVEDVANLAMFL 269
Query: 240 ASDLGSYINGAMIPVDGGRL 259
SD S+I G +I VDGG +
Sbjct: 270 LSDAASWITGQVINVDGGHM 289
>gb|AAF81239.1| (AF263012) putative beta-ketoacyl reductase [Streptomyces griseus
subsp. griseus]
Length = 274
Score = 103 bits (255), Expect = 2e-21
Identities = 81/268 (30%), Positives = 123/268 (45%), Gaps = 17/268 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L G+ F T +S GIG +A +LA G+ V +++R+E+ L+ E+I+ + V +
Sbjct: 10 LQGRTTFLTGASSGIGAVLATMLAAHGSSVALMARSEKELRLLAERIEADGGRAVA-VPG 68
Query: 66 DLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFM-EMSMEDWEEAVKLLLYPAIYL 123
DLT D + V+E + +G D G + F+ + E W + + L A +
Sbjct: 69 DLTDGDSVRAAVREAEEQLGPIDRLVHCAGEARNQAFLCDQDEEQWTATLDINLLGAFRV 128
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+A+VP M + G I+ +S+A K +P + + G+ + LA ELG G+ VN
Sbjct: 129 ARAVVPGMMERREGNIVMVSSIAGKRGLPANTSYCASKFGLNGMTQALASELGSFGVRVN 188
Query: 184 GIMPGIIRTDRMIQLAQDR---------AKREGK---TVEEALQEYAKPIPLGRLGEPEE 231
+ PG+ TD R AK G T E L+ L RL PEE
Sbjct: 189 AVCPGL--TDSPAATDGGRYGDAFMAAIAKHHGPPDLTWERYLRRAVNSTILRRLVRPEE 246
Query: 232 IGYLVAFLASDLGSYINGAMIPVDGGRL 259
I V FL SDL + G + VD G L
Sbjct: 247 IAAQVLFLLSDLSGGMTGQAVNVDAGAL 274
>pir||F82776 3-oxoacyl-[ACP] reductase XF0671 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105551|gb|AAF83481.1|AE003911_3
(AE003911) 3-oxoacyl-[ACP] reductase [Xylella
fastidiosa]
Length = 247
Score = 103 bits (255), Expect = 2e-21
Identities = 78/253 (30%), Positives = 117/253 (45%), Gaps = 15/253 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L G++A T +S+GIG VA +LA GA VI + + + +++ + + H
Sbjct: 5 LQGEVALVTGASRGIGAAVADLLADHGATVIGTATSVSGAQLIGDRL---ALLAGHGRAL 61
Query: 66 DLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+ + V E+ + G I + G + M M EDWE V L +
Sbjct: 62 DVNDTAAVGALVGEIAEQFGSVSILVNNAGITRDNLLMRMKDEDWESIVDTNLSSIFRTS 121
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
+A+V M + GRII SV A + + G ++LAKE+GP+GITVN
Sbjct: 122 RAVVRDMMKARKGRIINIASVVGVTGNAGQANYAAAKAGVIGFTKSLAKEVGPRGITVNV 181
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
+ PG I TD L+ E + +PLG LG+P +I + VAFLA+
Sbjct: 182 VAPGFIDTDMTRVLS-----------EGVRNDILNRVPLGHLGDPVDIAHAVAFLAAPAA 230
Query: 245 SYINGAMIPVDGG 257
YI G + V+GG
Sbjct: 231 RYITGETLHVNGG 243
>pir||A48950 aflatoxin biosynthesis protein Ver-1 - Aspergillus parasiticus
Length = 262
Score = 102 bits (253), Expect = 3e-21
Identities = 72/257 (28%), Positives = 130/257 (50%), Gaps = 9/257 (3%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+A T + +GIG +A L + GA V++ N + +R R K S V +
Sbjct: 7 LDGKVALVTGAGRGIGAAIAVALGERGAKVVV---NYAHCRRPRRKWLNRSRPMVPMLSQ 63
Query: 66 DLTKMDDLERTVK----ELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ D E T K +++ G DI + G G+ +++ E+++ ++
Sbjct: 64 SQADVGDPEATAKLMAETVRHFGYLDIVSSNAGIVSFGHLKDVTPEEFDRVFRVNTRGQF 123
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ + M R+G I+ S++ A + +P A+ + + A+ VR +A + G K IT
Sbjct: 124 FVAREAYRHM-REGGRIILTSSNTACVKGVPKHAVYSGSKGAIDTFVRCMAIDCGDKKIT 182
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPI-PLGRLGEPEEIGYLVAFLA 240
VN + PG I+TD + ++++ +E + E A + PL R+G P ++ +V+FLA
Sbjct: 183 VNAVAPGAIKTDMFLAVSREYIPNGETFTDEQVDECAAWLSPLNRVGLPVDVARVVSFLA 242
Query: 241 SDLGSYINGAMIPVDGG 257
SD +++G +I VDGG
Sbjct: 243 SDTAEWVSGKIIGVDGG 259
>sp|Q00791|STCU_EMENI VERSICOLORIN REDUCTASE >gi|1235633|gb|AAC49205.1| (U34740) putative
ketoreductase [Aspergillus nidulans]
Length = 264
Score = 102 bits (253), Expect = 3e-21
Identities = 74/257 (28%), Positives = 137/257 (52%), Gaps = 9/257 (3%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE--SNVEVHY- 62
L GK+A T + +GIG +A L + GA V++ N N + A EK+ +E SN +
Sbjct: 9 LDGKVALVTGAGRGIGAAIAVALGQRGAKVVV---NYANSREAAEKVVDEIKSNAQTAIS 65
Query: 63 IVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
I AD+ D + + + + +++ G DI + G G+ +++ ++++ ++
Sbjct: 66 IQADVGDPDAVTKLMDQAVEHFGYLDIVSSNAGIVSFGHVKDVTPDEFDRVFRVNTRGQF 125
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ + + R+G I+ S++ A + +P A+ + + A+ VR LA + G K IT
Sbjct: 126 FVAREAYRHL-REGGRIILTSSNTASVKGVPRHAVYSGSKGAIDTFVRCLAIDCGDKKIT 184
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPI-PLGRLGEPEEIGYLVAFLA 240
VN + PG I+TD + ++++ +E + E A + PL R+G P ++ +V+FLA
Sbjct: 185 VNAVAPGAIKTDMFLSVSREYIPNGETFTDEQVDECAAWLSPLNRVGLPVDVARVVSFLA 244
Query: 241 SDLGSYINGAMIPVDGG 257
SD +I+G +I VDGG
Sbjct: 245 SDAAEWISGKIIGVDGG 261
>gb|AAF18285.1| (AF088897) hypothetical protein; orf3 [Zymomonas mobilis]
Length = 254
Score = 102 bits (253), Expect = 3e-21
Identities = 73/259 (28%), Positives = 121/259 (46%), Gaps = 11/259 (4%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ D SGK+A T + GIG A AKA A V I+ R+E N++ + E +
Sbjct: 3 VSFDYSGKVALVTGAGTGIGRETALAFAKAKAYVAIIGRSENNIQETLRLVTEMGGQAIA 62
Query: 62 YIVADLTKMDDLERTV-KELKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYP 119
I AD+++ D ++ + K ++ G+ D F + G K ++ E+W+ + L
Sbjct: 63 -IQADVSQEDSIKAAIEKTVETFGKLDFAFNNAGIEHKAIPAADIPSEEWDRIISTNLNG 121
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+ K +PAM + G G I+ + S A + P + + GL + A + +
Sbjct: 122 VFFSMKHEIPAMLKSGSGSIVNTASGAGVKGFPGNGAYCASKFGLIGLSKAAALDYAKQH 181
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
+ +N + PGII T M +R EE + P+GR G P+EI V +L
Sbjct: 182 LRINVVAPGIIETPMM--------QRFTGGTEEGRETAIAQEPVGRAGHPKEIAGTVLWL 233
Query: 240 ASDLGSYINGAMIPVDGGR 258
SDL ++ G++ VDGG+
Sbjct: 234 CSDLAAFTTGSVFVVDGGQ 252
>gb|AAB65780.1| (AF002014) acetoacetyl-CoA reductase [Alcaligenes sp. SH-69]
Length = 245
Score = 102 bits (252), Expect = 4e-21
Identities = 73/252 (28%), Positives = 116/252 (45%), Gaps = 11/252 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
+S K+A+ T GIG + + L K G VI + + + + +H V
Sbjct: 1 MSQKVAYVTGGMGGIGTAICQRLHKEGFKVIAGCGPTRDHAKCWPSKRPWATRFMHPSVT 60
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
+ + +E K G D+ + G + F++MS EDW+ ++ L +TK
Sbjct: 61 WVIGIPPVEAFGKTKAEHGTIDVLVNNAGITRDRMFLKMSREDWDAVIETNLNSMFNVTK 120
Query: 126 ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
+V M KG+GRII +SV ++ + + M G LA+EL KG+TVN +
Sbjct: 121 QVVSDMVEKGWGRIINISSVNGEKGQAGQTNYSAAKAGMHGFSMALAQELATKGVTVNTV 180
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG I TD + + D L++ +P+ LGEP EI ++A+LAS+
Sbjct: 181 SPGYIGTDMVKAIRPD-----------VLEKIVATVPVKALGEPSEIASIIAWLASEENG 229
Query: 246 YINGAMIPVDGG 257
Y GA V+GG
Sbjct: 230 YATGADFSVNGG 241
>gb|AAD10276.1| (U47026) acetoacetyl-CoA reductase, NADPH-linked [Alcaligenes
latus]
Length = 245
Score = 102 bits (252), Expect = 4e-21
Identities = 76/256 (29%), Positives = 116/256 (44%), Gaps = 19/256 (7%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
++ KLA+ T GIG + + L K G VI R +K +E + A
Sbjct: 1 MTQKLAYVTGGMGGIGTSMCQRLHKDGFKVIAGC----GPSRDYQKWLDEQKALGYTFYA 56
Query: 66 DLTKMDDLERTVKELKNI----GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ + D + TV + + G D+ + G + G F +MS DW+ + L
Sbjct: 57 SVGNVADWDSTVVAFEKVKAEHGTVDVLVNNAGITRDGQFRKMSKADWQAVMSTNLDSMF 116
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
+TK ++ M KG+GRII +SV ++ + + M G LA+E+ KG+T
Sbjct: 117 NVTKQVIDGMLDKGWGRIINISSVNGEKGQFGQTNYSAAKAGMHGFTMALAQEVAAKGVT 176
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG I TD + + QD L + IP+ RLG PEEI +VA+LA
Sbjct: 177 VNTVSPGYIATDMVKAIRQD-----------VLDKIVSTIPIKRLGTPEEIASIVAWLAG 225
Query: 242 DLGSYINGAMIPVDGG 257
D + GA +GG
Sbjct: 226 DESGFTTGADFSCNGG 241
>gi|11437246 oxidoreductase UCPA [Homo sapiens]
Length = 245
Score = 102 bits (252), Expect = 4e-21
Identities = 70/253 (27%), Positives = 124/253 (48%), Gaps = 15/253 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+ TA+++GIG A A+ GA VI NE L +++++ ++ V
Sbjct: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKYPGIQTR--VL 57
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
D+TK +++ E++ + D+ F G G ++ +DW+ ++ L + + K
Sbjct: 58 DVTKKKQIDQFANEVERL---DVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 126 ALVPAMERKGFGRIIYSTSVAIK-EPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
A +P M + G II +SVA + + N + + + A+ GL +++A + +GI N
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
+ PG + T + + Q R R +A ++ K GR EEI L +LASD
Sbjct: 175 VCPGTVDTPSLQERIQARGNRS-----QARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229
Query: 245 SYINGAMIPVDGG 257
+Y+ G + +DGG
Sbjct: 230 AYVTGNPVIIDGG 242
>gb|AAB62288.1| (U24215) 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
[Pseudomonas putida] >gi|11138225|dbj|BAB17774.1|
(AB042508) 2,3-dihydroxy-2,3-dihydro-p-cumate
dehydrogenase [Pseudomonas putida]
>gi|1588765|prf||2209341E
2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
[Pseudomonas putida]
Length = 259
Score = 102 bits (251), Expect = 6e-21
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 13/257 (5%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKI--KEESNVEVH 61
+ L G++A T + GIG G+ L GA V +E L E++ K + VH
Sbjct: 9 LPLEGQVAVVTGGAHGIGLGIVERLLGLGARVTASDIDESGLSLLCERLAAKHADAIAVH 68
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
ADL++ + + ++ G I GG F+E + E + + L+ A
Sbjct: 69 --AADLSEEQGAQGLHRAAVERFGSVQILVNCAGGGVIRPFLEHTPETLKATIDRNLWTA 126
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
++ ++ +P M + +GRII + +++ +P+ A N + M GL LA+E +G+
Sbjct: 127 LWCSRVFLPDMLARQYGRIINIGADSVRNGLPDHAAYNAAKGGMHGLTTGLAREFARQGV 186
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + P + T+ +++ E Q + IP+GR+GE EE+ +V +LA
Sbjct: 187 TVNTVAPCAVNTEVWVRIKNAN--------PELAQRFLDVIPMGRVGEIEEVASMVGYLA 238
Query: 241 SDLGSYINGAMIPVDGG 257
+++ G +I V+GG
Sbjct: 239 QPEAAFVTGQVISVNGG 255
>pir||JC5856 polyketide synthase (EC 2.-.-.-) chain 7 - Actinomadura hibisca
>gi|2580448|dbj|BAA23150.1| (D87924) ORF 7 [Actinomadura
hibisca]
Length = 246
Score = 102 bits (251), Expect = 6e-21
Identities = 74/263 (28%), Positives = 118/263 (44%), Gaps = 24/263 (9%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
M +GK A T ++GIG VA LA+AGA+V + R++ A E ++ +
Sbjct: 1 MTDTSFAGKNALITGGTRGIGRAVALGLARAGANVTVCYRSDAESAAAMEAELAATDGKH 60
Query: 61 HYIVADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
H + AD+ D+ R + E+ +G D+ + G F ++ E+W V L
Sbjct: 61 HVLQADIGNAGDVRRLLDEVAARMGSLDVVVHNAGLISHVPFADLEPEEWHRIVDSNLTG 120
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALS-----NVVRIAMAGLVRTLAKE 174
+ +A +P + G V + + + +S + + G VR+L+KE
Sbjct: 121 MYLVVRAALPLLSEGG-------AVVGVGSKVALVGISQRTHYTAAKAGLIGFVRSLSKE 173
Query: 175 LGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGY 234
LGP GI VN + PGI TD+ L + +R Y L RLG+ +E+
Sbjct: 174 LGPLGIRVNLVAPGITETDQAAHLPPVQRER-----------YQSMTALKRLGQADEVAD 222
Query: 235 LVAFLASDLGSYINGAMIPVDGG 257
+V FLA Y+ G + VDGG
Sbjct: 223 VVLFLAGPGARYVTGETVNVDGG 245
>sp|P39482|DHG1_BACME GLUCOSE 1-DEHYDROGENASE I (GLCDH-I) >gi|80112|pir||JS0385 glucose
1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium
>gi|216268|dbj|BAA14099.1| (D90043) glucose
dehydrogenase [Bacillus megaterium]
>gi|228657|prf||1808263C glucose dehydrogenase I
[Bacillus megaterium]
Length = 261
Score = 101 bits (250), Expect = 7e-21
Identities = 82/256 (32%), Positives = 118/256 (46%), Gaps = 13/256 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRN-EENLKRAREKIKEESNVEVHYI 63
DL GK+ T SS G+G +A A A V++ R+ EE E+IK+ E +
Sbjct: 4 DLEGKVVVITGSSTGLGKAMAIRFATEKAKVVVNYRSKEEEANSVLEEIKKVGG-EAIAV 62
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+T D+ V+ +K G+ D+ + G P EMS+ DW + + L A
Sbjct: 63 KGDVTVESDVINLVQSSIKEFGKLDVMINNAGMENPVSSHEMSLSDWNKVIDTNLTGAFL 122
Query: 123 LTK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ A+ +E G +I +SV K P P + M + TLA E PKGI
Sbjct: 123 GSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN I PG I T + D +R + IP+G +GEPEEI + A+LAS
Sbjct: 183 VNNIGPGAINTPINAEKFADPEQRA---------DVESMIPMGYIGEPEEIAAVAAWLAS 233
Query: 242 DLGSYINGAMIPVDGG 257
SY+ G + DGG
Sbjct: 234 SEASYVTGITLFADGG 249
>sp|P72332|NODG_RHIS3 NODULATION PROTEIN G >gi|1531618|gb|AAB16895.1| (U53327) NodG
[Rhizobium sp. N33]
Length = 245
Score = 101 bits (249), Expect = 1e-20
Identities = 80/254 (31%), Positives = 122/254 (47%), Gaps = 16/254 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
+L+G+ A T +S GIG +ARVL GA V + E L E + E V
Sbjct: 3 ELTGRKALVTGASGGIGEAIARVLHAQGAIVGLHGTRVEKL----ETLAAELGDRVKLFP 58
Query: 65 ADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
A+L+ D+++ ++ + ++ DI + G K G F+ MS DW+ +++ L L
Sbjct: 59 ANLSNRDEVKALGQKAEADLEGVDILVNNAGITKDGLFVRMSDADWDTVLEVNLTAVFRL 118
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
T+ L M R+ GRII TSV P + M G ++LA+E+ + ITVN
Sbjct: 119 TRELTHPMMRRRHGRIINITSVVGVTGNPGQTNYCASKAGMIGFSKSLAQEIATRNITVN 178
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG I + M D+ K EA+ IP R+G E+ VA+LAS+
Sbjct: 179 CVAPGFIES-AMTDKLNDKQK-------EAIM---AAIPTRRMGTSVEVASAVAYLASNE 227
Query: 244 GSYINGAMIPVDGG 257
+Y+ G I V+GG
Sbjct: 228 AAYVTGQTIHVNGG 241
>pir||T36782 probable gluconate dehydrogenase - Streptomyces coelicolor
>gi|5441755|emb|CAB46779.1| (AL096811) putative
gluconate dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 253
Score = 101 bits (249), Expect = 1e-20
Identities = 74/254 (29%), Positives = 116/254 (45%), Gaps = 14/254 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
D+ G+ A T SS+GIG +AR LA+AG VI+ R+ + L +A + E VH V
Sbjct: 8 DIGGRTALVTGSSRGIGLALARGLAEAGCRVILNGRDGDRLAKAAAGLPGE----VHTAV 63
Query: 65 ADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+T + + E + +G DI + G +E + DW + L A +
Sbjct: 64 FDVTDGPSVTAGIAEAEERVGPLDILVNNAGMQLRAPLLEFADADWHRILDTNLTTAFLV 123
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+ M +G G+I+ S+ + P IA + A+ L + + + GP G+ VN
Sbjct: 124 GREAARRMTERGHGKIVNICSLQSEVVRPGIAPYAATKGALKMLTKGMCADWGPYGVQVN 183
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
G+ PG I T+ L +D EE P GR G E++ + FLAS
Sbjct: 184 GLGPGYIETELTRPLVED---------EEFSTWVRGRTPAGRWGRTEDLVGGLLFLASPA 234
Query: 244 GSYINGAMIPVDGG 257
++ G ++ VDGG
Sbjct: 235 ADFVGGQILYVDGG 248
>sp|P50163|TRN2_DATST TROPINONE REDUCTASE-II (TR-II) >gi|539027|pir||B48674 tropinone
reductase (EC 1.1.1.236) II - jimsonweed
>gi|4388843|pdb|2AE2|A Chain A, Tropinone Reductase-Ii
Complexed With Nadp+ And Pseudotropine
>gi|4388844|pdb|2AE2|B Chain B, Tropinone Reductase-Ii
Complexed With Nadp+ And Pseudotropine
>gi|4139967|pdb|2AE1| Tropinone Reductase-Ii
>gi|424162|gb|AAA33282.1| (L20474) tropinone
reductase-II [Datura stramonium]
Length = 260
Score = 101 bits (249), Expect = 1e-20
Identities = 73/255 (28%), Positives = 121/255 (46%), Gaps = 9/255 (3%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
+L G A T S+GIG+G+ LA GA V SRN++ L + + + +V V
Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKG-FKVEASV 64
Query: 65 ADLTKMDDLERTVKELKNI--GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
DL+ + + + + N G+ +I + G + ++ED+ + + A +
Sbjct: 65 CDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYH 124
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L+ P ++ G +++ +SV+ +P A+ + AM L R LA E I V
Sbjct: 125 LSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRV 184
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
NG+ PG+I T + QD ++E L + L R+GEP+E+ +VAFL
Sbjct: 185 NGVGPGVIATSLVEMTIQDPEQKEN------LNKLIDRCALRRMGEPKELAAMVAFLCFP 238
Query: 243 LGSYINGAMIPVDGG 257
SY+ G +I VDGG
Sbjct: 239 AASYVTGQIIYVDGG 253
>sp|P50205|PHBB_RHIME ACETOACETYL-COA REDUCTASE >gi|790552|gb|AAA90983.1| (U17226)
acetoacetyl CoA reductase [Sinorhizobium meliloti]
Length = 241
Score = 101 bits (249), Expect = 1e-20
Identities = 79/254 (31%), Positives = 120/254 (47%), Gaps = 22/254 (8%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVHY--IVA 65
++A T S+GIG + L AG V + N+E K ++ES + V+ + +
Sbjct: 3 RVALVTGGSRGIGAAICVALKAAGYKVAANYAGNDERAKA----FEQESGIPVYKWDVSS 58
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
+D + R +L G DI + G + F +M+ E W E + L +T
Sbjct: 59 YQACVDGIARVEADL---GPVDILVNNAGITRDAMFHKMTPEQWGEVIGTNLTGVFNMTH 115
Query: 126 ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
L M +GFGRI+ +S+ ++ + + GL + LA+E KGITVN I
Sbjct: 116 PLWSGMRDRGFGRIVNISSINGQKGQMGQVNYSAAKAGDLGLTKALAQEGAAKGITVNAI 175
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKP-IPLGRLGEPEEIGYLVAFLASDLG 244
PG I T+ + + E+ L E P IP+GRLGEPEE+ V FLASD
Sbjct: 176 CPGYIGTEMVRAVP-----------EKVLNERIIPQIPVGRLGEPEEVARCVVFLASDDA 224
Query: 245 SYINGAMIPVDGGR 258
+I G+ I +GG+
Sbjct: 225 GFITGSTISANGGQ 238
>pir||T44434 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)
[imported] - Moritella marina
>gi|6045047|dbj|BAA85256.1| (AB021978) 3-oxoacyl-[acyl
carrier protein] reductase homolog [Moritella marina]
Length = 244
Score = 101 bits (248), Expect = 1e-20
Identities = 75/255 (29%), Positives = 110/255 (42%), Gaps = 16/255 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ S K T +S+GIG +A AK GA VI + + + +R + + +
Sbjct: 1 MSFSSKTVLVTGASRGIGRAIAEHFAKLGATVIGTATSAQGAERIGAYLGDAG----FGL 56
Query: 64 VADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
++T D ++ E+K +G DI + G F+ M ++W + L
Sbjct: 57 ELNVTSQDSVDALYAEIKTQVGHIDILVNNAGITADNIFLRMKEDEWCNVIDTNLTSLYR 116
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L K + M ++ GRII SV A + + G ++LA E+ +GITV
Sbjct: 117 LCKPCLRGMMKQRHGRIINIGSVVGTTGNGGQANYAAAKSGLLGFTKSLASEVASRGITV 176
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I TD +L EE Q +P RLG EI V FLASD
Sbjct: 177 NAVAPGFIETDMTAELT-----------EEQKQTILAQVPTSRLGSTTEIAETVGFLASD 225
Query: 243 LGSYINGAMIPVDGG 257
SYI G I V+GG
Sbjct: 226 GASYITGETIHVNGG 240
>sp|P40288|DHG_BACME GLUCOSE 1-DEHYDROGENASE >gi|98132|pir||A33528 glucose
1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium
>gi|142975|gb|AAA22475.1| (J04805) glucose dehydrogenase
(EC 1.1.1.47) [Bacillus megaterium]
Length = 261
Score = 100 bits (246), Expect = 2e-20
Identities = 81/256 (31%), Positives = 119/256 (45%), Gaps = 13/256 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEEN-LKRAREKIKEESNVEVHYI 63
DL GK+ T SS G+G +A A A V++ R++E+ E+IK+ E +
Sbjct: 4 DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGG-EAIAV 62
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+T D+ V+ +K G+ D+ + G P EMS+ DW + + L A
Sbjct: 63 KGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFL 122
Query: 123 LTK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ A+ +E G +I +SV K P P + M + TLA E PKGI
Sbjct: 123 GSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN I PG I T + D +R + IP+G +GEPEEI + A+LAS
Sbjct: 183 VNNIGPGAINTPINAEKFADPEQRA---------DVESMIPMGYIGEPEEIAAVAAWLAS 233
Query: 242 DLGSYINGAMIPVDGG 257
SY+ G + DGG
Sbjct: 234 SEASYVTGITLFADGG 249
>emb|CAA05517.1| (AJ002527) glucitol-6-phosphate dehydrogenase [Clostridium
beijerinckii]
Length = 271
Score = 100 bits (246), Expect = 2e-20
Identities = 78/269 (28%), Positives = 124/269 (45%), Gaps = 20/269 (7%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++L GK A T + GIG VA+ GA+V++ N + ++ N + YI
Sbjct: 6 LNLEGKTAIVTGGASGIGKAVAQEFLNNGANVVVCDMNPNKPEF------DDHNGHMEYI 59
Query: 64 VADLTKMDDLERTVKELKNI-GEPDIFFFSTG---------GPKPGYFMEMSMEDWEEAV 113
V ++ D +E+ +++ K I G DI + G +P E+ W++ +
Sbjct: 60 VTNVADRDSVEKMIEKAKEITGTIDIIVNNAGINIPRLLVDKKEPKGKFELDENVWDKVM 119
Query: 114 KLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAK 173
+ + + M +G G II +S + E ++ + A+ L R+ AK
Sbjct: 120 NVNVKGVFLCAQVAAREMASQGKGVIINMSSESGLEGSEGQSVYAASKNAVNSLTRSWAK 179
Query: 174 ELGPKGITVNGIMPGIIRTD--RMIQLAQDRAKREGKTVEEALQEYAKP--IPLGRLGEP 229
ELG GI V G+ PGI+ R ++ A G TVEE Y+K PLGR G+
Sbjct: 180 ELGKLGIRVIGVAPGILEATGLRTLEYETALAYTRGITVEELRAGYSKTSTTPLGRSGKL 239
Query: 230 EEIGYLVAFLASDLGSYINGAMIPVDGGR 258
E+ LV +LASD SYI+G + GG+
Sbjct: 240 SEVADLVCYLASDRASYIHGVTYNIAGGK 268
>sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) >gi|2117439|pir||I39853
glucose 1-dehydrogenase (EC 1.1.1.47) 2 - Bacillus
megaterium >gi|216270|dbj|BAA14100.1| (D90044) glucose
dehydrogenase [Bacillus megaterium]
>gi|228658|prf||1808263D glucose dehydrogenase II
[Bacillus megaterium]
Length = 261
Score = 99.8 bits (245), Expect = 3e-20
Identities = 78/256 (30%), Positives = 120/256 (46%), Gaps = 13/256 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSR-NEENLKRAREKIKEESNVEVHYI 63
DL K+ T SKG+G +A + + V++ R NEE +++I EE+ + +
Sbjct: 4 DLKDKVVVVTGGSKGLGRAMAVRFGQEQSKVVVNYRSNEEEALEVKKEI-EEAGGQAIIV 62
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+TK +D+ V+ +K G D+ + G P E+S+E+W + + L A
Sbjct: 63 RGDVTKEEDVVNLVETAVKEFGSLDVMINNAGVENPVPSHELSLENWNQVIDTNLTGAFL 122
Query: 123 LTK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ A+ +E G +I +SV P P + M + TLA E PKGI
Sbjct: 123 GSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN I PG I T + D +R + IP+G +G+PEEI + AFLAS
Sbjct: 183 VNNIGPGAIDTPINAEKFADPEQRA---------DVESMIPMGYIGKPEEIASVAAFLAS 233
Query: 242 DLGSYINGAMIPVDGG 257
SY+ G + DGG
Sbjct: 234 SQASYVTGITLFADGG 249
>pir||F70677 hypothetical protein Rv3549c - Mycobacterium tuberculosis (strain
H37RV) >gi|1666111|emb|CAB05057.1| (Z82098) hypothetical
protein Rv3549c [Mycobacterium tuberculosis]
Length = 259
Score = 99.1 bits (243), Expect = 5e-20
Identities = 75/258 (29%), Positives = 118/258 (45%), Gaps = 24/258 (9%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ L+G++ T +G+G G++ V A+ GA VI +R + + E H
Sbjct: 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCAR----------RAVDGQPYEFH 59
Query: 62 YIVADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKL-LLYP 119
D+ D ++R V E+ + G D+ + GG E + + V+L +L P
Sbjct: 60 R--CDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAP 117
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+ A V + G I+ SV+ + P P A + + L TLA E PK
Sbjct: 118 LLVSQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPK- 176
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
+ VN ++ G++ T+R D E++ A +PLGRL P +IG+ AFL
Sbjct: 177 VRVNAVVVGMVETERSELFYGDA---------ESIARVAATVPLGRLARPADIGWAAAFL 227
Query: 240 ASDLGSYINGAMIPVDGG 257
ASD SYI+GA + V GG
Sbjct: 228 ASDAASYISGATLEVHGG 245
>sp|P06234|NODG_RHIME NODULATION PROTEIN G (HOST-SPECIFICITY OF NODULATION PROTEIN C)
>gi|78008|pir||C24706 nodulation protein nodG -
Rhizobium meliloti plasmid >gi|46304|emb|CAA68649.1|
(Y00604) nodG gene product (AA 1 - 245) [Sinorhizobium
meliloti] >gi|46308|emb|CAA27962.1| (X04379) nodG gene
product (AA 1-245) [Sinorhizobium meliloti]
>gi|226079|prf||1410222C nodG gene [Rhizobium meliloti]
Length = 245
Score = 98.3 bits (241), Expect = 8e-20
Identities = 78/257 (30%), Positives = 121/257 (46%), Gaps = 22/257 (8%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
+L+G+ A T +S IG +ARVL GA V + E L E + E V
Sbjct: 3 ELTGRKALVTGASGAIGGAIARVLHAQGAIVGLHGTQIEKL----ETLATELGDRVKLFP 58
Query: 65 ADLTKMDDL----ERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
A+L D++ +R +L+ + DI + G K G F+ M+ DW+ +++ L
Sbjct: 59 ANLANRDEVKALGQRAEADLEGV---DILVNNAGITKDGLFLHMADPDWDIVLEVNLTAM 115
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
LT+ + M R+ GRII TSVA P + M G ++LA+E+ + I
Sbjct: 116 FRLTREITQQMIRRRNGRIINVTSVAGAIGNPGQTNYCASKAGMIGFSKSLAQEIATRNI 175
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + PG I + D+ + K ++ IP+ R+G E+ VA+LA
Sbjct: 176 TVNCVAPGFIES-----AMTDKLNHKQK------EKIMVAIPIHRMGTGTEVASAVAYLA 224
Query: 241 SDLGSYINGAMIPVDGG 257
SD +Y+ G I V+GG
Sbjct: 225 SDHAAYVTGQTIHVNGG 241
>emb|CAB69765.1| (AL137187) putative dehydrogenase/reductase [Streptomyces
coelicolor A3(2)]
Length = 255
Score = 98.3 bits (241), Expect = 8e-20
Identities = 73/255 (28%), Positives = 116/255 (44%), Gaps = 18/255 (7%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
+L+GK A T ++GIG + R L +AGA+VI +R+ A E + ++
Sbjct: 12 ELAGKRALVTGGTRGIGAAIVRRLLEAGAEVITTARS------ATGPAPEGAG----FVQ 61
Query: 65 ADLTKMDDLERTV-KELKNIGEPDIFFFSTGGPKPGYF-MEMSMEDWEEAVKLLLYPAIY 122
AD+ + E L+ +G DI + GG +P + + E+W + + L L ++
Sbjct: 62 ADVRTLAGAEALAGAALEALGGVDILVHNAGGARPHKDGLVIPDEEWLDTLNLNLLASVR 121
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L LVP M + G I++ +S A+ P P + A+ LA L P G+ V
Sbjct: 122 LNSLLVPGMRERRSGAIVHISSAAVAPPAPPFLHYQAAKAALDNYSAGLAATLAPSGVRV 181
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG T RE +A + PLGR G P++I + V +L SD
Sbjct: 182 NTVSPGRTAT------PGGEETREHWASLDAGPAPSGTAPLGRDGLPDDIAHAVLYLVSD 235
Query: 243 LGSYINGAMIPVDGG 257
++ G + VDGG
Sbjct: 236 RAGWVTGTSLAVDGG 250
>gi|8923752 peroxisomal trans 2-enoyl CoA reductase; putative short chain
alcohol dehydrogenase [Homo sapiens]
>gi|7688188|emb|CAB89810.1| (AJ250303) alcohol
dehydrogenase, short chain [Homo sapiens]
Length = 303
Score = 98.3 bits (241), Expect = 8e-20
Identities = 70/258 (27%), Positives = 119/258 (45%), Gaps = 13/258 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE----SNVEVH 61
L G++AF T + GIG + + L + G++V+I SR E LK A ++++ V
Sbjct: 16 LQGQVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
I ++ +++ VK L G+ + + GG +S + W ++ L +
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTGS 135
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
Y+ KA+ + ++ G I+ + V K P S R + L ++LA E GI
Sbjct: 136 FYMCKAVYSSWMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
+N + PG+I +Q + G + + + IP R+G PEE+ +V FL
Sbjct: 195 RINCVAPGVI-------YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247
Query: 241 SDLGSYINGAMIPVDGGR 258
S S+I G + VDGGR
Sbjct: 248 SPAASFITGQSVDVDGGR 265
>gb|AAG30942.1| (AF314502) glucose dehydrogenase [Bacillus subtilis]
Length = 261
Score = 98.3 bits (241), Expect = 8e-20
Identities = 81/256 (31%), Positives = 118/256 (45%), Gaps = 13/256 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEEN-LKRAREKIKEESNVEVHYI 63
DL GK+ T SS G+G +A A A A V++ R++E+ E+IK+ E +
Sbjct: 4 DLKGKVVVITGSSTGLGKAMAIRFATAKAKVVVNYRSKEDEANSVLEEIKKVGG-EAIAV 62
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+T D+ V+ +K G+ D+ + G P EMS+ DW + + L A
Sbjct: 63 KGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWIKVIDTNLTGAFL 122
Query: 123 LTK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
++ A+ +E G +I +SV K P P + M + TLA E PKGI
Sbjct: 123 GSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN I PG I T + D E + IP+G +GEPEE + A+LAS
Sbjct: 183 VNNIGPGAINTPINAEKFAD---------PEQSADVESMIPMGYIGEPEETAAVAAWLAS 233
Query: 242 DLGSYINGAMIPVDGG 257
SY+ G + DGG
Sbjct: 234 SEASYVTGITLFADGG 249
>gb|AAA87616.1| (L34880) polyketide reductase [Streptomyces sp.]
Length = 262
Score = 97.9 bits (240), Expect = 1e-19
Identities = 73/257 (28%), Positives = 123/257 (47%), Gaps = 5/257 (1%)
Query: 5 DLSGKLAFTTASSKGIGFGVAR-VLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
D + ++A T + GIG V R LA G V + +R+E + +++ + S +EV
Sbjct: 3 DAADRVALVTGGTSGIGLAVGRRKLALDGTRVFLCARDESAVTGTVKEL-QASGLEVEGT 61
Query: 64 VADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+ D ++R V+ +N + DI + G G +++ + W + V L A
Sbjct: 62 SCDVRSTDAVDRLVRTARNPLRAIDIVVNNAGRGGGGVTAQITDDLWSDVVDTNLGGAFR 121
Query: 123 LTKALVPA--MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+T+A++ M+ G+GRII S K+ + A + + + G + +A EL GI
Sbjct: 122 VTRAVLTGGGMQEHGWGRIINIASTGGKQGVALGAPYSASKSGLIGFTKAVALELARTGI 181
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + PG + T + Q A G T ++ L+++ IPLGR +E+ +V +L
Sbjct: 182 TVNAVCPGYVETPMAQGVRQRYAAFWGITEDDVLEKFRAKIPLGRYSTSDEVAGMVHYLV 241
Query: 241 SDLGSYINGAMIPVDGG 257
SD I I V GG
Sbjct: 242 SDSADSITAQAINVCGG 258
>gb|AAD38447.1|AF099742_1 (AF099742) putative short-chain dehydrogenase/reductase [Rattus
norvegicus] >gi|6491860|gb|AAF14047.1|AF021854_1
(AF021854) peroxisomal 2,4-dienoyl CoA reductase
px-2,4-DCR#1 [Rattus norvegicus]
Length = 303
Score = 97.9 bits (240), Expect = 1e-19
Identities = 74/258 (28%), Positives = 121/258 (46%), Gaps = 13/258 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE----SNVEVH 61
L ++A T + GIG ++R L G +V+I SR + L A ++++ S+ +V
Sbjct: 16 LQNQVAVVTGGATGIGKAISRELLHLGCNVVIASRKLDRLTAAVDELRASQPPSSSTQVT 75
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
I ++ K +++ VK L G+ + + GG +++ + W+ ++ L
Sbjct: 76 AIQCNIRKEEEVNNLVKSTLAKYGKINFLVNNAGGQFMAPAEDITAKGWQAVIETNLTGT 135
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
Y+ KA+ + K G I + V + P A S R + L +T+A G+
Sbjct: 136 FYMCKAVYNSW-MKDHGGSIVNIIVLLNNGFPTAAHSGAARAGVYNLTKTMALTWASSGV 194
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
+N + PG I + Q A D G+T+ E E IP R+G PEEI LV FL
Sbjct: 195 RINCVAPGTIYS----QTAVDNYGELGQTMFEMAFEN---IPAKRVGLPEEISPLVCFLL 247
Query: 241 SDLGSYINGAMIPVDGGR 258
S S+I G +I VDGG+
Sbjct: 248 SPAASFITGQLINVDGGQ 265
>gb|AAF05857.1|AC011698_8 (AC011698) putative short-chain type dehydrogenase/reductase
[Arabidopsis thaliana]
Length = 270
Score = 97.9 bits (240), Expect = 1e-19
Identities = 81/278 (29%), Positives = 126/278 (45%), Gaps = 45/278 (16%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ L+G++A T SS+GIG +A LA+ GA ++I N + E++ E N
Sbjct: 12 LPLAGRVAIVTGSSRGIGRAIAIHLAELGARIVI---NYTSKAADAERVASEIN------ 62
Query: 64 VADLTKMDDLE----RTVKELKNIGEPD------------------IFFFSTGGPKPGY- 100
D +++ R + N+ EP I S G P Y
Sbjct: 63 --DFPVREEITGKGPRAIVVQANVSEPSQVKSMFDAAESAFEAPVHILVNSAGILDPKYP 120
Query: 101 -FMEMSMEDWEEAVKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNV 159
+ S+ED++ + A +K +++ G GRII TS + P
Sbjct: 121 TIADTSVEDFDHTFSVNTKGAFLCSKEAANRLKQGGGGRIILLTSSQTRSLKPGFGAYAA 180
Query: 160 VRIAMAGLVRTLAKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAK 219
+ A+ +V+ LAKEL GIT N + PG I T+ +GKT E +++ A
Sbjct: 181 SKAAVETMVKILAKELKGTGITANCVAPGPIATEMFF---------DGKT-PELVEKIAA 230
Query: 220 PIPLGRLGEPEEIGYLVAFLASDLGSYINGAMIPVDGG 257
P GR+GE +++ LV FLA D G ++NG +IPV+GG
Sbjct: 231 ESPFGRVGEAKDVVPLVGFLAGDGGEWVNGQIIPVNGG 268
>sp|P23238|PHBB_ZOORA ACETOACETYL-COA REDUCTASE >gi|95026|pir||S06998 acetoacetyl-CoA
reductase (EC 1.1.1.36) - Zoogloea ramigera
Length = 241
Score = 97.5 bits (239), Expect = 1e-19
Identities = 73/252 (28%), Positives = 119/252 (46%), Gaps = 18/252 (7%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
++A T S+GIG ++ L AG V ++ A + K E+ + V+ D++
Sbjct: 3 RVALVTGGSRGIGAAISIALKAAGYKVAASYAGNDD---AAKPFKAETGIAVYKW--DVS 57
Query: 69 KMDD-LERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
+ +E K ++G D+ + G K F +M+ + W + L +T +
Sbjct: 58 SYEACVEGIAKVEADLGPIDVLVNNAGITKDAMFHKMTPDQWNAVINTNLTGLFNMTHPV 117
Query: 128 VPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMP 187
M + FGRI+ +S+ ++ A + + G + LA+E KGITVN I P
Sbjct: 118 WSGMRDRSFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKALAQEGAAKGITVNAICP 177
Query: 188 GIIRTDRMIQLAQDRAKREGKTVEEALQEYAKP-IPLGRLGEPEEIGYLVAFLASDLGSY 246
G I T+ + + E+ L E P IP+GRLGEP+EI +V FLASD +
Sbjct: 178 GYIGTEMVRAIP-----------EKVLNERIIPQIPVGRLGEPDEIARIVVFLASDEAGF 226
Query: 247 INGAMIPVDGGR 258
I G+ I +GG+
Sbjct: 227 ITGSTISANGGQ 238
>sp|P39484|DHG3_BACME GLUCOSE 1-DEHYDROGENASE III (GLCDH-III) >gi|2117440|pir||I40224
glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus
megaterium >gi|216376|dbj|BAA01475.1| (D10625) glucose
dehydrogenase [Bacillus megaterium]
Length = 261
Score = 97.5 bits (239), Expect = 1e-19
Identities = 74/255 (29%), Positives = 115/255 (45%), Gaps = 11/255 (4%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL K+ T S G+G +A + A V+I N E +K EE+ + +
Sbjct: 4 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 63
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+TK +D+ V+ +K G D+ + G P E+S+++W + + L A
Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123
Query: 124 TK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
++ A+ +E G +I +SV P P + M + TLA E PKGI V
Sbjct: 124 SREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKQMTETLALEYAPKGIRV 183
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG + T + D +R + IP+G +G+PEE+ + AFLAS
Sbjct: 184 NNIGPGAMNTPINAEKFADPVQRA---------DVESMIPMGYIGKPEEVAAVAAFLASS 234
Query: 243 LGSYINGAMIPVDGG 257
SY+ G + DGG
Sbjct: 235 QASYVTGITLFADGG 249
>emb|CAC11396.1| (AL445063) 3-ketoacyl-acyl carrier protein reductase related
protein [Thermoplasma acidophilum]
Length = 255
Score = 97.5 bits (239), Expect = 1e-19
Identities = 75/261 (28%), Positives = 128/261 (48%), Gaps = 18/261 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+A T +SKG+G +A A GA V I ++E + ++K + E+ A
Sbjct: 5 LEGKIALITGASKGLGRAIAEKFADEGAKVAINYNSDE---KGALEVKRRTGGEIFQ--A 59
Query: 66 DLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLL---LYPAI 121
D++ D + R E+ + +G+ DI ++G Y M D + +++ L AI
Sbjct: 60 DVSNRDQIRRMANEIHSKLGKIDILVNNSG---IWYLMPFDQYDESKVRRMIDVNLMGAI 116
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
Y T +P ++ K I +++ I N ++ + + L + LA +L GI
Sbjct: 117 YTTLEFLPDLKEKRGVIINMASNAGIGTAARNTTFYSITKAGIIMLTKRLAFDLSEYGIR 176
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN I PG I TD I +++ E K +E+ ++ L +G+PE IG FLAS
Sbjct: 177 VNAIAPGWIETDLTIG---GKSEEEIKRLED---DFRSRTTLKMIGKPEYIGNAAVFLAS 230
Query: 242 DLGSYINGAMIPVDGGRLNSV 262
Y+NG ++ +DGGR++++
Sbjct: 231 KDSEYMNGQVMVIDGGRIDNL 251
>sp|P80869|DHG2_BACSU GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) (GDH-II) (GENERAL STRESS
PROTEIN 74) (GSP74) >gi|7430991|pir||G69755 glucose
1-dehydrogenase homolog ycdF - Bacillus subtilis
>gi|2415734|dbj|BAA22244.1| (AB000617) YcdF [Bacillus
subtilis] >gi|2632569|emb|CAB12077.1| (Z99105) similar
to glucose 1-dehydrogenase [Bacillus subtilis]
Length = 258
Score = 97.1 bits (238), Expect = 2e-19
Identities = 71/256 (27%), Positives = 123/256 (47%), Gaps = 13/256 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL+GK A T SSKGIG +A K +V++ ++ + +I +++ + +
Sbjct: 4 DLTGKTAIVTGSSKGIGKAIAERFGKEKMNVVVNYHSDPSGADETLEIIKQNGGKAVSVE 63
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
AD++K + ++ + L++ G D+ ++G EMS+EDW+ + + +
Sbjct: 64 ADVSKEEGIQALLDTALEHFGTLDVMVNNSGFNGVEAMPHEMSLEDWQRVIDVNVTGTFL 123
Query: 123 LTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
KA + M + G ++ +SV + P P + + + + TLA KGI
Sbjct: 124 GAKAALNHMMKNNIKGNVLNISSVHQQIPRPVNVQYSTSKGGIKMMTETLALNYADKGIR 183
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN I PG I T+ + + EE+ Q+ K IP+ G+PEE+ A+L S
Sbjct: 184 VNAIAPGTIATESNVDTKK----------EESRQKQLKKIPMKAFGKPEEVAAAAAWLVS 233
Query: 242 DLGSYINGAMIPVDGG 257
+ SY+ GA + VDGG
Sbjct: 234 EEASYVTGATLFVDGG 249
>sp|P39485|DHG4_BACME GLUCOSE 1-DEHYDROGENASE IV (GLCDH-IV) >gi|2117441|pir||I40225
glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus
megaterium >gi|216378|dbj|BAA01476.1| (D10626) glucose
dehydrogenase [Bacillus megaterium]
Length = 261
Score = 96.7 bits (237), Expect = 2e-19
Identities = 74/255 (29%), Positives = 115/255 (45%), Gaps = 11/255 (4%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL K+ T S G+G +A + A V+I N E +K EE+ + +
Sbjct: 4 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 63
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+TK +D+ V+ +K G D+ + G P E+S+++W + + L A
Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123
Query: 124 TK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
++ A+ +E G +I +SV P P + M + TLA E PKGI V
Sbjct: 124 SREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 183
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG + T + D +R + IP+G +G+PEE+ + AFLAS
Sbjct: 184 NNIGPGAMNTPINAEKFADPVQRA---------DVESMIPMGYIGKPEEVAAVAAFLASS 234
Query: 243 LGSYINGAMIPVDGG 257
SY+ G + DGG
Sbjct: 235 QASYVTGITLFADGG 249
>sp|P10528|DHGA_BACME GLUCOSE 1-DEHYDROGENASE A >gi|80114|pir||S00812 glucose
1-dehydrogenase (EC 1.1.1.47) A - Bacillus megaterium
>gi|39635|emb|CAA30931.1| (X12370) glucose dehydrogenase
A (AA 1 - 261) [Bacillus megaterium]
Length = 261
Score = 96.3 bits (236), Expect = 3e-19
Identities = 74/255 (29%), Positives = 115/255 (45%), Gaps = 11/255 (4%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL K+ T S G+G +A + A V+I N E +K EE+ + +
Sbjct: 4 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 63
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+TK +D+ V+ +K G D+ + G P E+S+++W + + L A
Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123
Query: 124 TK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
++ A+ +E G +I +SV P P + M + TLA E PKGI V
Sbjct: 124 SREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 183
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG + T + D +R + IP+G +G+PEE+ + AFLAS
Sbjct: 184 NNIGPGAMNTPINAEKFADPEQRA---------DVESMIPMGYIGKPEEVAAVAAFLASS 234
Query: 243 LGSYINGAMIPVDGG 257
SY+ G + DGG
Sbjct: 235 QASYVTGITLFADGG 249
>sp|O07575|YHDF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN CITA-SSPB INTERGENIC REGION
>gi|7431015|pir||D69825 glucose 1-dehydrogenase homolog
yhdF - Bacillus subtilis >gi|2226201|emb|CAA74490.1|
(Y14082) hypothetical protein [Bacillus subtilis]
>gi|2633280|emb|CAB12784.1| (Z99109) similar to glucose
1-dehydrogenase [Bacillus subtilis]
Length = 289
Score = 96.3 bits (236), Expect = 3e-19
Identities = 75/258 (29%), Positives = 118/258 (45%), Gaps = 14/258 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+A T GIG A AK GAD+ IL +E + K E+ NV I
Sbjct: 43 LKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIPG 102
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKP-GYFMEMSMEDWEEAVKLLLYPAIYL 123
D+ + E+ V++ + + G+ DI + P + +S E E+ + ++ ++
Sbjct: 103 DVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFHM 162
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
TK +P ++ II +TS+ E + + + A+ R++AK L KGI VN
Sbjct: 163 TKKALPHLQEGC--AIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVN 220
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG I T + EE ++++ P+GR G+P E LASD
Sbjct: 221 AVAPGPIWTPLI----------PATFPEEKVKQHGLDTPMGRPGQPVEHAGAYVLLASDE 270
Query: 244 GSYINGAMIPVDGGRLNS 261
SY+ G I V+GGR S
Sbjct: 271 SSYMTGQTIHVNGGRFIS 288
>dbj|BAB09479.1| (AB012246) Brn1-like protein [Arabidopsis thaliana]
Length = 261
Score = 96.3 bits (236), Expect = 3e-19
Identities = 81/264 (30%), Positives = 123/264 (45%), Gaps = 21/264 (7%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVII--LSRNEENLKRAREKIKEESNVEVHYI 63
L+G++A T SS+GIG +A LA+ GA ++I +R+ E + A E V
Sbjct: 8 LAGRVAIVTGSSRGIGRAIAIHLAELGAKIVINYTTRSTEADQVAAEINSSAGTVPQPIA 67
Query: 64 VADLTKMDDLERTVKELKNIGEP------DIFFFSTGGPKPGY--FMEMSMEDWEEAVKL 115
V L + + + +K L + E I S G P Y +E+++ K+
Sbjct: 68 VVFLADISEPSQ-IKSLFDAAEKAFNSPVHILVNSAGILNPNYPTIANTPIEEFDRIFKV 126
Query: 116 LLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKEL 175
+ K ++R G GRII TS + IP + A+ +V+ LAKEL
Sbjct: 127 NTRGSFLCCKEAAKRLKRGGGGRIILLTSSLTEALIPGQGAYTASKAAVEAMVKILAKEL 186
Query: 176 GPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYL 235
GIT N + PG + T+ +GK+ EE + + P GRLGE ++I +
Sbjct: 187 KGLGITANCVSPGPVATEMFF---------DGKS-EETVMNIIERSPFGRLGETKDIASV 236
Query: 236 VAFLASDLGSYINGAMIPVDGGRL 259
V FLASD G +ING +I +G L
Sbjct: 237 VGFLASDGGEWINGQVIVANGAFL 260
>emb|CAB58271.1| (AL121849) putative dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 252
Score = 96.0 bits (235), Expect = 4e-19
Identities = 69/256 (26%), Positives = 113/256 (43%), Gaps = 17/256 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+ + A T ++ IG +A A GA V++ R+ E + + I+ ++ A
Sbjct: 3 LADRTALVTGATSNIGRAIAEAFAAEGAHVVVSGRSAERGREVVDGIRAAGG-RADFVHA 61
Query: 66 DLTKMDDLERTV-KELKNI--GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
DL R + +E + G D+ + G PG + E ++ + + +
Sbjct: 62 DLDGSAAASRALAREATRVLGGRVDVLVNNAGIYPPGTTTDTDEETFDRVYAVNVKAPFF 121
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
LT L PAM R G G +I S + +P AL + + A+ L R A E G +G+ V
Sbjct: 122 LTAVLAPAMVRAGGGTVINLGSWIARLGVPVGALYSSTKGAVETLTRAWAAEFGARGVRV 181
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I PG+++T ++ G P GR+G PE I +LA D
Sbjct: 182 NAISPGVVQTPPPGEVHPAEVMMRG-------------TPAGRMGTPEAIASAAVYLAGD 228
Query: 243 LGSYINGAMIPVDGGR 258
S+++G ++ VDGGR
Sbjct: 229 ESSFVHGTVLDVDGGR 244
>sp|P12310|DHG_BACSU GLUCOSE 1-DEHYDROGENASE >gi|7430990|pir||D69629 glucose
1-dehydrogenase (EC 1.1.1.47) - Bacillus subtilis
>gi|1805462|dbj|BAA09024.1| (D50453) glucose
dehydrogenase [Bacillus subtilis]
>gi|2632694|emb|CAB12201.1| (Z99106) glucose
1-dehydrogenase [Bacillus subtilis]
Length = 261
Score = 95.6 bits (234), Expect = 5e-19
Identities = 78/258 (30%), Positives = 121/258 (46%), Gaps = 17/258 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE---SNVEVH 61
DL GK+ T ++ G+G +A K A V+I N + K+ ++KEE + E
Sbjct: 4 DLKGKVVAITGAASGLGKAMAIRFGKEQAKVVI---NYYSNKQDPNEVKEEVIKAGGEAV 60
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ D+TK +D++ V+ +K G DI + G P EM ++DW++ + L A
Sbjct: 61 VVQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSHEMPLKDWDKVIGTNLTGA 120
Query: 121 IYLTK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
++ A+ +E G +I +SV P P + + + TLA E PKG
Sbjct: 121 FLGSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKG 180
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN I PG I T + D ++ + IP+G +GEPEEI + A+L
Sbjct: 181 IRVNNIGPGAINTPINAEKFADPKQKA---------DVESMIPMGYIGEPEEIAAVAAWL 231
Query: 240 ASDLGSYINGAMIPVDGG 257
AS SY+ G + DGG
Sbjct: 232 ASKEASYVTGITLFADGG 249
>gb|AAF69800.1|AF232011_1 (AF232011) peroxisomal trans 2-enoyl CoA reductase [Mus musculus]
Length = 303
Score = 95.6 bits (234), Expect = 5e-19
Identities = 73/258 (28%), Positives = 117/258 (45%), Gaps = 13/258 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRA----REKIKEESNVEVH 61
L ++A T GIG V+R L G +V+I SR + L A R + S+ EV
Sbjct: 16 LKNQVAVVTGGGTGIGKAVSRELLHLGCNVVIASRKLDRLTAAVDELRASLPPSSSAEVS 75
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
I ++ K +++ VK L G+ + + GG +++ + W ++ L
Sbjct: 76 AIQCNIRKEEEVSNLVKSTLAKYGKINFLVNNGGGQFMAPVEDITAKGWHAVIETNLTGT 135
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
Y+ K + + R+ G I+ + V + P A + R + L +++A G+
Sbjct: 136 FYMCKEVYNSWMREHGGSIV-NIIVLLNNGFPTAAHTGAAREGVYNLTKSMALAWASSGV 194
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
+N + PG I + Q A D G+T+ E + IP+ LG PEEI L FL
Sbjct: 195 RINCVAPGTIYS----QTAVDNYGEMGQTLFEMAFD---SIPVSALGVPEEISLLARFLL 247
Query: 241 SDLGSYINGAMIPVDGGR 258
S SYI G +I VDGG+
Sbjct: 248 SPAASYITGQLINVDGGQ 265
>pir||G82644 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase XF1726
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9106794|gb|AAF84535.1|AE003996_4 (AE003996)
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase
[Xylella fastidiosa]
Length = 255
Score = 95.6 bits (234), Expect = 5e-19
Identities = 78/258 (30%), Positives = 117/258 (45%), Gaps = 17/258 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI- 63
D G++A T ++ G+G AR A+ GA V++ R+ E + I E +
Sbjct: 6 DFKGQVALVTGAAAGMGLATARGFAQGGASVVLADRDGERAAQEAAAIVAEGGTAIGLAC 65
Query: 64 -VADLTKMDDL-ERTVKELKNIGEPDIFFFSTGG--PKPGYFMEMSMEDWEEAVKLLLYP 119
V+D ++ L E+TV E + F F+ G K F E + E+++ + + L
Sbjct: 66 DVSDEAQVAALVEKTVAEYGRLD----FAFNNAGVMAKIAPFAEATSEEFDRVIGINLRG 121
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
K + M+R+G G I+ + SV I + + GL R A E KG
Sbjct: 122 VWLCMKYELQQMQRQGSGVIVNNASVGALTGNVGIGAYIASKHGVLGLTRAAALEYCKKG 181
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN + PG I T Q+A+D +EA + P+GR G PEEI V +L
Sbjct: 182 IRVNAVNPGTIDT----QIARDVVGGS----DEAFAKLGASAPIGRAGRPEEIASAVLWL 233
Query: 240 ASDLGSYINGAMIPVDGG 257
S GSY+ G + VDGG
Sbjct: 234 CSPGGSYVIGEGLTVDGG 251
>sp|P50197|LINC_PSEPA 2,5-DICHLORO-2,5-CYCLOHEXADIENE-1,4-DIOL DEHYDROGENASE (2,5-DDOL
DEHYDROGENASE) >gi|286173|dbj|BAA03444.1| (D14595)
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase
[Sphingomonas paucimobilis]
Length = 250
Score = 95.2 bits (233), Expect = 7e-19
Identities = 75/257 (29%), Positives = 118/257 (45%), Gaps = 17/257 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DLSGK T GIG +L +GA+V + N+E A E + S + Y
Sbjct: 3 DLSGKTIIVTGGGSGIGRATVELLVASGANVPVADINDE----AGEAVVATSGGKAAYFR 58
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGY-FMEMSMEDWEEAVKLLLYPAIY 122
D+ + +D++ V + L G D F + P+ G E+S+E + +++ + +
Sbjct: 59 CDIAQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTGTFL 118
Query: 123 LTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
K + AM +G G I+ + S A +P + A+ GL R A + G GI
Sbjct: 119 CMKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAAADYGKHGIR 178
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPI-PLGRLGEPEEIGYLVAFLA 240
VN ++PG +RT M+Q A D + L+ Y I P+GR EP E +L
Sbjct: 179 VNALVPGAVRTP-MLQRAMDN--------DAGLEPYLNSIHPIGRFSEPHEQAQAAVWLL 229
Query: 241 SDLGSYINGAMIPVDGG 257
SD S++ G+ + DGG
Sbjct: 230 SDAASFVTGSCLAADGG 246
>sp|Q11020|Y07E_MYCTU PUTATIVE OXIDOREDUCTASE RV1350 >gi|7431079|pir||E70740 probable
fabG2 protein - Mycobacterium tuberculosis (strain
H37RV) >gi|1419053|emb|CAA99983.1| (Z75555) fabG2
[Mycobacterium tuberculosis]
Length = 247
Score = 95.2 bits (233), Expect = 7e-19
Identities = 69/258 (26%), Positives = 119/258 (45%), Gaps = 22/258 (8%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV- 64
L+ + A T ++G+G + + GA V++ + NL+ K +V V
Sbjct: 5 LNARTAVITGGAQGLGLAIGQRFVAEGARVVL---GDVNLEATEVAAKRLGGDDVALAVR 61
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+T+ DD++ ++ ++ G D+ + G + M+ E +++ + + L
Sbjct: 62 CDVTQADDVDILIRTAVERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNG 121
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
T+ M + G I+ +SV+ K + + + + G+ + AKEL GI VN
Sbjct: 122 TRLAAAIMRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVN 181
Query: 184 GIMPGIIR---TDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
I PG+IR T+ M Q D+ E +P+GR GEP E+ + FLA
Sbjct: 182 AIAPGLIRSAMTEAMPQRIWDQKLAE--------------VPMGRAGEPSEVASVAVFLA 227
Query: 241 SDLGSYINGAMIPVDGGR 258
SDL SY+ G ++ V GGR
Sbjct: 228 SDLSSYMTGTVLDVTGGR 245
>pir||F75374 probable ketoacyl reductase - Deinococcus radiodurans (strain R1)
>gi|6459386|gb|AAF11180.1|AE002005_9 (AE002005) ketoacyl
reductase, putative [Deinococcus radiodurans]
Length = 328
Score = 95.2 bits (233), Expect = 7e-19
Identities = 53/190 (27%), Positives = 100/190 (51%), Gaps = 2/190 (1%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHY 62
+ DL GK T S+G+G + R LA GA + +++R E +L+ A E ++ EV
Sbjct: 25 RYDLQGKHVLLTGGSRGLGLALGRELAGRGARLTLVARTERDLRLAAEDLRGRG-AEVQI 83
Query: 63 IVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
I AD+T + + ++ G+ D+ G + G M+ +D+ + +++ + +
Sbjct: 84 IAADVTDPGAGQHILDAAQSFGDVDVLLHCAGLIQSGPLANMTEQDFRDVMEIHAFAPLR 143
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
L + L+P + R+ GR++ TS+ K +P++ ++ + A GL + L EL G+TV
Sbjct: 144 LVRTLLPQLSRRQ-GRVLLVTSIGGKVAVPHLVPYSMSKFAAVGLGQGLRSELAAHGVTV 202
Query: 183 NGIMPGIIRT 192
+ PG++RT
Sbjct: 203 TTVCPGLMRT 212
>gb|AAF69798.1|AF232009_1 (AF232009) peroxisomal trans 2-enoyl CoA reductase [Homo sapiens]
Length = 303
Score = 95.2 bits (233), Expect = 7e-19
Identities = 69/258 (26%), Positives = 117/258 (44%), Gaps = 13/258 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE----SNVEVH 61
L G++A T + GIG + + L + G++V+I SR E LK A ++++ V
Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
I ++ +++ VK L G+ + + GG +S + W ++ L
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
Y+ KA+ + ++ G I+ + V K P S R + L ++LA E GI
Sbjct: 136 FYMCKAVYSSWMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
+N + PG+I +Q + G + + + IP R+G PEE+ +V FL
Sbjct: 195 RINCVAPGVI-------YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247
Query: 241 SDLGSYINGAMIPVDGGR 258
S S+I G + VDGGR
Sbjct: 248 SPAASFITGQSVDVDGGR 265
>gb|AAF69799.1|AF232010_1 (AF232010) peroxisomal trans 2-enoyl CoA reductase [Cavia sp.]
Length = 302
Score = 95.2 bits (233), Expect = 7e-19
Identities = 75/259 (28%), Positives = 120/259 (45%), Gaps = 16/259 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKE----ESNVEVH 61
L + A T GIG +A+ L G +V+I SR + L+ A E++K + EV
Sbjct: 16 LQNRAAIVTGGGTGIGKAIAKELLHLGCNVVIASRKFDRLRAAAEELKATLPPSNKAEVT 75
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
I ++ K +++ +K L G+ D + GG +S + W ++ L
Sbjct: 76 PIQCNIRKEEEVNNLMKSTLALYGKIDFLVNNGGGQFWSSPEHISSKGWHAVIETNLTGT 135
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
Y+ KA + ++ G I+ + + P +A S R + L ++LA GI
Sbjct: 136 FYMCKAAYNSWMKEHGGAIV--NIIILLNGQPFVAHSGAARGGVYNLTKSLALGWARSGI 193
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTV-EEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
+N + PG + + Q A D GKT+ +A Q+ IP RLG PEE+ LV FL
Sbjct: 194 RINCVAPGTVYS----QTAMDNYGDMGKTLFADAFQK----IPAKRLGVPEEVSSLVCFL 245
Query: 240 ASDLGSYINGAMIPVDGGR 258
S S+I G ++ VDGG+
Sbjct: 246 LSPAASFITGQLVNVDGGQ 264
>pir||S01227 glucose 1-dehydrogenase (EC 1.1.1.47) B - Bacillus megaterium
Length = 263
Score = 94.8 bits (232), Expect = 9e-19
Identities = 80/258 (31%), Positives = 120/258 (46%), Gaps = 15/258 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRA--REKIKEESNVEVHY 62
DL GK+ T SS G+G +A A A V++ R++E+ + E+IK+ E
Sbjct: 4 DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEEIKKVGG-EAIA 62
Query: 63 IVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ D+T D+ V+ +K G+ D+ + G P EMS+ DW + + L A
Sbjct: 63 VKGDVTVESDVINLVQSAIKEFGKLDVMINNAGMENPVSSHEMSLSDWNKVIDTNLTGAF 122
Query: 122 YLTK-ALVPAMERKGFGRIIYSTSV-AIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
++ A+ +E G +I +SV K P P + M + TLA E PKG
Sbjct: 123 LGSREAIKYFVENDIKGIVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYAPKG 182
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN I PG I T + D +R + IP+G +GEPEE+ + A+L
Sbjct: 183 IRVNNIGPGAINTPINAEKFADPEQRA---------DVESMIPMGYIGEPEELAAVAAWL 233
Query: 240 ASDLGSYINGAMIPVDGG 257
AS SY+ G + DGG
Sbjct: 234 ASSEASYVTGITLFADGG 251
>pir||S34724 probable oxidoreductase (EC 1.1.1.-) - Serratia marcescens
>gi|395949|emb|CAA80898.1| (Z25281) oxido-reductase
[Serratia marcescens]
Length = 254
Score = 94.8 bits (232), Expect = 9e-19
Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 13/257 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL+GK F T + +GIG A L KAG D+ ++E+ +A + + Y
Sbjct: 3 DLAGKKVFITGAEQGIGRATAERLIKAGCDIYFHYHSDESGPKALVALAHSLGQKAAYGY 62
Query: 65 ADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFM-EMSMEDWEEAVKLLLYPAIY 122
ADL D+ R V + +G DI + GG ++ E+ W+ + + + +
Sbjct: 63 ADLIDTDETLRCVSAGAEFLGGIDILINNVGGIVGRKWLGEIDRAFWQTVIDVNMTTMLN 122
Query: 123 LTKALVPAMERKGFGR-IIYSTSVAIKEP-IPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+T++ +P ++ G II S+A + + + + A+ R+LA ELG GI
Sbjct: 123 VTQSALPHLKAAPNGASIINLASLAGRAGGHAGSLVYSATKGAVLTWTRSLAAELGEHGI 182
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN + PG+I R T + + +E + IPLGR G P+++ +AFLA
Sbjct: 183 RVNAVAPGLILGTRF---------HNRHTTQASAEETVRAIPLGRAGTPDDVARAIAFLA 233
Query: 241 SDLGSYINGAMIPVDGG 257
++ +I+GA + ++GG
Sbjct: 234 AEYDGFISGATLDINGG 250
>emb|CAC11810.1| (AL445065) polyketide synthase chain 7 related protein
[Thermoplasma acidophilum]
Length = 258
Score = 94.8 bits (232), Expect = 9e-19
Identities = 73/260 (28%), Positives = 117/260 (44%), Gaps = 17/260 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
D SG A T + +GIG +A L AGA+V + + + + E +H V
Sbjct: 9 DFSGSTAVVTGAFQGIGKAIADALLDAGAEVYGIDKAFPD-----HGVDEGRFHGLHGSV 63
Query: 65 ADLTKMDDLERTVKELKN-----IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
L + L V E + I+F+ + + +D+E + L
Sbjct: 64 DSLDDIASLRDRVAETSGRLDFLVNNAGIYFYKK-------IEDSTEDDYERITSVNLKG 116
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+T+ + + + + I+ SV+ + P L ++ + + L R L+ +LG G
Sbjct: 117 YFLMTREFLQLLRKSDYPSIVNIASVSGQRPEAGHPLYSMTKGGILALTRALSADLGMLG 176
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN + PG I+T + D+A++ G +E ++YA LGR GE E+ +V FL
Sbjct: 177 IRVNSVSPGNIKTPMNDEDILDQARKRGLDPDEVERQYAAESVLGRRGEAAEVASVVLFL 236
Query: 240 ASDLGSYINGAMIPVDGGRL 259
S SYINGA I VDGG L
Sbjct: 237 LSKGASYINGADIVVDGGLL 256
>emb|CAC11888.1| (AL445065) glucose 1-dehydrogenase related protein [Thermoplasma
acidophilum]
Length = 255
Score = 94.8 bits (232), Expect = 9e-19
Identities = 67/254 (26%), Positives = 114/254 (44%), Gaps = 14/254 (5%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL K+ T +S GIG +A G+ VI LS I + + +I
Sbjct: 4 DLRDKVVIVTGASMGIGRAIAERFVDEGSKVIDLS------------IHDPGEAKYDHIE 51
Query: 65 ADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+T D ++ ++ + K G + + G G MSM +W + + L+ Y
Sbjct: 52 CDVTNPDQVKASIDHIFKEYGSISVLVNNAGIESYGKIESMSMGEWRRIIDVNLFGYYYA 111
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+K +P M R I+ +SV N + + A+ GL +++A + P + N
Sbjct: 112 SKFAIPYMIRSRDPSIVNISSVQASIITKNASAYVTSKHAVIGLTKSIALDYAPL-LRCN 170
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ P I T + + A+ + +E+ + E+ P+ R+G+P+E+ VAFLAS
Sbjct: 171 AVCPATIDTPLVRKAAELEVGSDPMRIEKKISEWGHEHPMQRIGKPQEVASAVAFLASRE 230
Query: 244 GSYINGAMIPVDGG 257
S+I G + VDGG
Sbjct: 231 ASFITGTCLYVDGG 244
>sp|Q08632|SDR1_PICAB SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE >gi|421786|pir||S34678
short-chain alcohol dehydrogenase (EC 1.1.1.-) - Norway
spruce >gi|395223|emb|CAA52213.1| (X74115) short-chain
alcohol dehydrogenase [Picea abies]
Length = 271
Score = 94.4 bits (231), Expect = 1e-18
Identities = 79/267 (29%), Positives = 126/267 (46%), Gaps = 19/267 (7%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEV 60
L + L G++A T +S+GIG +A +A+ GA V+I S N+ + I +S
Sbjct: 15 LPLPLGGRVAIVTGASRGIGREIALNMAEKGAKVVIHYSSNQHAAEEVASIINNKSPSSG 74
Query: 61 HYIVADLTKMDDLERT-VKELKNIGEP-----DIFFFSTGGPKPGY--FMEMSMEDWEEA 112
+ A + K D E + V +L + E I + G Y + S E+W+
Sbjct: 75 DGVRAIVCKADVAEPSQVAQLFDTAEHAFGPLHIVVNNAGVTDSKYPTLAQTSDEEWDRI 134
Query: 113 VKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLA 172
++ A ++ + R G GRII +S + PIP + A+ + R LA
Sbjct: 135 FQVNCKGAFLCSREAAKRVVRGGGGRIINISSSLVAMPIPRYGAYTASKAAVEMMTRILA 194
Query: 173 KELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEI 232
+EL IT N + PG + TD GK+ E A++ K P RLG+ E++
Sbjct: 195 QELRGTQITANCVAPGPVATDMFF---------AGKS-EAAVEAGVKSNPFERLGKVEDV 244
Query: 233 GYLVAFLASDLGSYINGAMIPVDGGRL 259
LVAFLASD G ++N ++ V+GG++
Sbjct: 245 APLVAFLASDEGEWVNAQVVRVNGGQV 271
>pir||D83416 probable short-chain dehydrogenase PA1828 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947814|gb|AAG05217.1|AE004609_4 (AE004609) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 255
Score = 94.4 bits (231), Expect = 1e-18
Identities = 72/258 (27%), Positives = 124/258 (47%), Gaps = 12/258 (4%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL GK+AF + +S+GIG +A++LA+ GA VI+ SR + + + I E + I
Sbjct: 8 DLDGKIAFVSGASRGIGEAIAKLLAQQGAHVIVSSRKIDGCQAVADAITAEGG-KATAIA 66
Query: 65 ADLTKMDDLERTVKELK-NIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
+ +M+ ++ +++ G DI + P+ +E + +++ V + + +
Sbjct: 67 CHIGEMEQIQNVFAQIREQFGRLDILVNNAATNPQFCNVLETDLGAFQKTVDVNIRGYYF 126
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
++ M+ G G II S+ P + +V + A+ + + AKE GI
Sbjct: 127 MSIEGGKLMKEHGGGSIINVASINGVSPGEFQGIYSVTKAAVISMTKVFAKECAQFGIRC 186
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N ++PG+ T L ++ A R ALQ IPL R+ EP E+ V +LAS+
Sbjct: 187 NALLPGLTDTKFASALVKNDAIR-----NLALQR----IPLKRVAEPSEMAGAVLYLASE 237
Query: 243 LGSYINGAMIPVDGGRLN 260
SY G + VDGG L+
Sbjct: 238 ASSYTTGVALNVDGGFLS 255
>sp|P37769|KDUD_ECOLI 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE (2-KETO-3-DEOXYGLUCONATE
OXIDOREDUCTASE) >gi|7430992|pir||C65067
2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125) -
Escherichia coli (strain K-12) >gi|882735|gb|AAB40489.1|
(U29581) ORF_f253 [Escherichia coli]
>gi|1789208|gb|AAC75881.1| (AE000368)
2-deoxy-D-gluconate 3-dehydrogenase [Escherichia coli
K12]
Length = 253
Score = 93.6 bits (229), Expect = 2e-18
Identities = 76/261 (29%), Positives = 121/261 (46%), Gaps = 24/261 (9%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI-- 63
L GK+A T G+G G+A LA+AG D++ + N+ E I++ + + ++
Sbjct: 8 LEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGI-----NIVEPTETIEQVTALGRRFLSL 62
Query: 64 VADLTKMDD----LERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
ADL K+D L+R V E +I DI + G + +E S +DW++ + L +
Sbjct: 63 TADLRKIDGIPALLDRAVAEFGHI---DILVNNAGLIRREDALEFSEKDWDDVMNLNIKS 119
Query: 120 AIYLTKALVPAMERKGFG-RIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
++++A +G G +II S+ + + + + G+ R +A E
Sbjct: 120 VFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTASKSGVMGVTRLMANEWAKH 179
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
I VN I PG + T+ QL D E+ E IP GR G P ++ + F
Sbjct: 180 NINVNAIAPGYMATNNTQQLRAD---------EQRSAEILDRIPAGRWGLPSDLMGPIVF 230
Query: 239 LASDLGSYINGAMIPVDGGRL 259
LAS Y+NG I VDGG L
Sbjct: 231 LASSASDYVNGYTIAVDGGWL 251
>pir||S02299 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium
Length = 262
Score = 93.2 bits (228), Expect = 3e-18
Identities = 82/258 (31%), Positives = 120/258 (45%), Gaps = 16/258 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRA--REKIKEESNVEVHY 62
DL GK+ T SS G+G +A A A V++ R++E+ + E+IK+ E
Sbjct: 4 DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEEIKKVGG-EAIA 62
Query: 63 IVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ D+T D+ V+ +K G+ D+ + G P EMS+ DW + + L A
Sbjct: 63 VKGDVTVESDVINLVQSAIKEFGKLDVMINNAGMENPVSSHEMSLSDWNKVIDTNLTGAF 122
Query: 122 YLTK-ALVPAMERKGFGRIIYSTSV-AIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
++ A+ +E G +I +SV K P P + M + TLA E PKG
Sbjct: 123 LGSREAIKYFVENDIKGTVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYAPKG 182
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN I PG I T + D +R + IP+G +GEPEEI VA+L
Sbjct: 183 IRVNNIGPGAINTPINAEKFADPEER---------ADVESMIPMGYIGEPEEIA-AVAWL 232
Query: 240 ASDLGSYINGAMIPVDGG 257
AS SY+ G + DGG
Sbjct: 233 ASSEASYVTGITLFADGG 250
>sp|P07999|DHGB_BACME GLUCOSE 1-DEHYDROGENASE B
Length = 262
Score = 93.2 bits (228), Expect = 3e-18
Identities = 82/258 (31%), Positives = 120/258 (45%), Gaps = 16/258 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRA--REKIKEESNVEVHY 62
DL GK+ T SS G+G +A A A V++ R++E+ + E+IK+ E
Sbjct: 4 DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEEIKKVGG-EAIA 62
Query: 63 IVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ D+T D+ V+ +K G+ D+ + G P EMS+ DW + + L A
Sbjct: 63 VKGDVTVESDVINLVQSAIKEFGKLDVMINNAGMENPVSSHEMSLSDWNKVIDTNLTGAF 122
Query: 122 YLTK-ALVPAMERKGFGRIIYSTSV-AIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
++ A+ +E G +I +SV K P P + M + TLA E PKG
Sbjct: 123 LGSREAIKYFVENDIKGTVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYAPKG 182
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN I PG I T + D +R + IP+G +GEPEEI VA+L
Sbjct: 183 IRVNNIGPGAINTPINAEKFADPEQR---------ADVESMIPMGYIGEPEEIA-AVAWL 232
Query: 240 ASDLGSYINGAMIPVDGG 257
AS SY+ G + DGG
Sbjct: 233 ASSEASYVTGITLFADGG 250
>pir||D70635 hypothetical protein Rv1928c - Mycobacterium tuberculosis (strain
H37RV) >gi|1806234|emb|CAB06498.1| (Z84498) hypothetical
protein Rv1928c [Mycobacterium tuberculosis]
Length = 255
Score = 93.2 bits (228), Expect = 3e-18
Identities = 73/260 (28%), Positives = 126/260 (48%), Gaps = 23/260 (8%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL GK A T +S GIG VA +AGA V I +R+ + L++ ++I S +V +
Sbjct: 8 DLHGKRALITGASTGIGKRVALAYVEAGAQVAIAARHLDALEKLADEIGT-SGGKVVPVC 66
Query: 65 ADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+++ + + ++ +G DI + G ++M +E+++ +
Sbjct: 67 CDVSQHQQVTSMLDQVTAELGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLT 126
Query: 124 TKALVPAMERKGFGRIIYSTS------VAIKEPIPNIALSNVVRIAMAGLVRTLAKELGP 177
+A AM ++G G +I +T+ + + + + + S + A+ L + +A EL P
Sbjct: 127 AQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCAS---KAAVIHLTKAMAVELAP 183
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVA 237
I VN + PG I T+ + + + E K IPLGRLG PEE+ L
Sbjct: 184 HKIRVNSVSPGYILTELVEPYTEYQPLWEPK------------IPLGRLGRPEELAGLYL 231
Query: 238 FLASDLGSYINGAMIPVDGG 257
+LAS+ SY+ G+ I +DGG
Sbjct: 232 YLASEASSYMTGSDIVIDGG 251
>sp|P39345|IDNO_ECOLI GLUCONATE 5-DEHYDROGENASE (5-KETO-D-GLUCONATE 5-REDUCTASE)
>gi|1361067|pir||S56492 hypothetical 27.6K protein
(pepa-gntv intergenic region) - Escherichia coli
>gi|537108|gb|AAA97163.1| (U14003) ORF_f254 [Escherichia
coli] >gi|1790717|gb|AAC77223.1| (AE000497)
5-keto-D-gluconate 5-reductase [Escherichia coli K12]
Length = 254
Score = 92.8 bits (227), Expect = 4e-18
Identities = 70/258 (27%), Positives = 120/258 (46%), Gaps = 11/258 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK T S++GIGF +A L K GA +II E + A EK+ +E ++
Sbjct: 7 LAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQE-GIQAVAAPF 65
Query: 66 DLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
++T +++ V+ + K+IG D+ + G + F E ++W + + + ++
Sbjct: 66 NVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVS 125
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
+A+ M + G++I S+ + I + A+ L R + EL I VNG
Sbjct: 126 QAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNG 185
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
I PG +T+ L +D E K P R G+P+E+ FL+S
Sbjct: 186 IAPGYFKTEMTKALVED---------EAFTAWLCKRTPAARWGDPQELIGAAVFLSSKAS 236
Query: 245 SYINGAMIPVDGGRLNSV 262
++NG ++ VDGG L +V
Sbjct: 237 DFVNGHLLFVDGGMLVAV 254
>pir||S36090 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus subtilis
>gi|142955|gb|AAA22463.1| (M12276) glucose dehydrogenase
(EC 1.1.1.47) [Bacillus subtilis]
Length = 260
Score = 92.4 bits (226), Expect = 5e-18
Identities = 78/258 (30%), Positives = 121/258 (46%), Gaps = 18/258 (6%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE---SNVEVH 61
DL GK+ T ++ G+G +A K A V+I N + K+ ++KEE + E
Sbjct: 4 DLKGKVVAITGAASGLGKAMAIRFGKEQAKVVI---NYYSNKQDPNEVKEEVIKAGGEAV 60
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ D+TK +D++ V+ +K G DI + G P EM ++DW++ + L A
Sbjct: 61 VVQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSHEMPLKDWDKVIGTNLTGA 120
Query: 121 IYLTK-ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
++ A+ +E G +I +SV P P + + + TLA E PKG
Sbjct: 121 FLGSREAIKYFVENDIKGNVINMSSVHAF-PWPLFVHYAASKGGIKLMTETLALEYAPKG 179
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN I PG I T + D ++ + IP+G +GEPEEI + A+L
Sbjct: 180 IRVNNIGPGAINTPINAEKFADPKQKA---------DVESMIPMGYIGEPEEIAAVAAWL 230
Query: 240 ASDLGSYINGAMIPVDGG 257
AS SY+ G + DGG
Sbjct: 231 ASKEASYVTGITLFADGG 248
>pir||C70675 hypothetical protein Rv3530c - Mycobacterium tuberculosis (strain
H37RV) >gi|1666130|emb|CAB05047.1| (Z82098) hypothetical
protein Rv3530c [Mycobacterium tuberculosis]
Length = 260
Score = 92.4 bits (226), Expect = 5e-18
Identities = 71/260 (27%), Positives = 120/260 (45%), Gaps = 8/260 (3%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L K+ + G+G +A A+ GAD+++ +R+ E L ++I + V +
Sbjct: 5 LKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDVAKQIIDTGRRAVA-VRT 63
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFF---FSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
D+T DD+ V+ L G+ D+ F KP + E +A++L +
Sbjct: 64 DITDDDDVSNLVQATLAAYGKADVLINNAFRVPSMKP--LAGTTFEHIRDAIELSALGTL 121
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
L +A PA+ + G I+ S+ I+ P + + + + +LA ELG +GI
Sbjct: 122 RLIQAFTPALAQS-HGAIVNVNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIR 180
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG I D + +A + G TV++ Q A L RL +E+ + FLAS
Sbjct: 181 VNSVAPGYIWGDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS 240
Query: 242 DLGSYINGAMIPVDGGRLNS 261
DL S I G + V+ G ++
Sbjct: 241 DLASGITGQTLDVNCGEYHT 260
>sp|P05406|FIXR_BRAJA FIXR PROTEIN >gi|77956|pir||S01065 probable dehydrogenase (EC
1.1.1.-) fixR - Bradyrhizobium japonicum
>gi|580771|emb|CAA29530.1| (X06167) fixR gene product
(AA 1 - 278) [Bradyrhizobium japonicum]
Length = 278
Score = 91.3 bits (223), Expect = 1e-17
Identities = 75/260 (28%), Positives = 115/260 (43%), Gaps = 30/260 (11%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K+ T +S+GIG A++ ++AG +I +R + +R + + + +V DL
Sbjct: 37 KVMLLTGASRGIGHATAKLFSEAGWRIISCARQPFDGERCPWEAGNDDHFQV-----DLG 91
Query: 69 KMDDLERTVKELKN--IGEPDIFFFSTGGPKPGY-------FMEMSMEDWEEAVKLLLYP 119
L R + E+K G P + G P + S + W L L
Sbjct: 92 DHRMLPRAITEVKKRLAGAPLHALVNNAGVSPKTPTGDRMTSLTTSTDTWMRVFHLNLVA 151
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVV-RIAMAGLVRTLAKELGPK 178
I L + L + R G I+ TS+A P + + A+A L R LA + P
Sbjct: 152 PILLAQGLFDEL-RAASGSIVNVTSIAGSRVHPFAGSAYATSKAALASLTRELAHDYAPH 210
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
GI VN I PG IRTD + A+ R IPL R+G P+E+ ++ F
Sbjct: 211 GIRVNAIAPGEIRTDMLSPDAEARV--------------VASIPLRRVGTPDEVAKVIFF 256
Query: 239 LASDLGSYINGAMIPVDGGR 258
L SD SY+ GA +P++GG+
Sbjct: 257 LCSDAASYVTGAEVPINGGQ 276
>pir||S74996 enoyl-[acyl-carrier-protein] reductase (NADH) (EC 1.3.1.9) -
Synechocystis sp. (strain PCC 6803)
>gi|1652111|dbj|BAA17036.1| (D90902)
enoyl-[acyl-carrier-protein] reductase [Synechocystis
sp.]
Length = 278
Score = 91.3 bits (223), Expect = 1e-17
Identities = 84/265 (31%), Positives = 125/265 (46%), Gaps = 25/265 (9%)
Query: 4 IDLSGKLAFTT--ASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKE-----ES 56
+DLSGK AF T A+++ I +G+A+ L +AGA++ + +E R +K++E
Sbjct: 22 LDLSGKHAFVTGIANNRSIAWGIAQQLHQAGAEIGVSYLPDEK-GRFEKKVRELTEPLHP 80
Query: 57 NVEVHYIVADLTKMDDLERTVKELKNIGEPDIFF----FSTGGPKPGYFMEMSMEDWEEA 112
+ + V D ++D L +VKE G+ DI F+ G + ++ E + +A
Sbjct: 81 TLVLPGDVQDDAQVDALFHSVKE--KWGKLDILIHCLAFADKSGLTGNYTDIPKEAFSQA 138
Query: 113 VKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLA 172
+++ Y L + P M G II T + IPN L V + + VR LA
Sbjct: 139 MEISTYSLGRLARGAKPLMTNGG--SIITLTYFGGVKVIPNYNLMGVAKAGLEMTVRYLA 196
Query: 173 KELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEI 232
ELGP+ I VNGI G IRT A + + + + PL R E+
Sbjct: 197 AELGPQNIRVNGISAGPIRT---------LASSAVGGILDMIHHVEEVAPLKRTVTQTEV 247
Query: 233 GYLVAFLASDLGSYINGAMIPVDGG 257
G AFLASDL S I G +I VD G
Sbjct: 248 GNTAAFLASDLSSGITGQIIYVDSG 272
>sp|P73016|FABI_SYNY3 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] (NADH-DEPENDENT
ENOYL-ACP REDUCTASE)
Length = 258
Score = 91.3 bits (223), Expect = 1e-17
Identities = 84/265 (31%), Positives = 125/265 (46%), Gaps = 25/265 (9%)
Query: 4 IDLSGKLAFTT--ASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKE-----ES 56
+DLSGK AF T A+++ I +G+A+ L +AGA++ + +E R +K++E
Sbjct: 2 LDLSGKHAFVTGIANNRSIAWGIAQQLHQAGAEIGVSYLPDEK-GRFEKKVRELTEPLHP 60
Query: 57 NVEVHYIVADLTKMDDLERTVKELKNIGEPDIFF----FSTGGPKPGYFMEMSMEDWEEA 112
+ + V D ++D L +VKE G+ DI F+ G + ++ E + +A
Sbjct: 61 TLVLPGDVQDDAQVDALFHSVKE--KWGKLDILIHCLAFADKSGLTGNYTDIPKEAFSQA 118
Query: 113 VKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLA 172
+++ Y L + P M G II T + IPN L V + + VR LA
Sbjct: 119 MEISTYSLGRLARGAKPLMTNGG--SIITLTYFGGVKVIPNYNLMGVAKAGLEMTVRYLA 176
Query: 173 KELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEI 232
ELGP+ I VNGI G IRT A + + + + PL R E+
Sbjct: 177 AELGPQNIRVNGISAGPIRT---------LASSAVGGILDMIHHVEEVAPLKRTVTQTEV 227
Query: 233 GYLVAFLASDLGSYINGAMIPVDGG 257
G AFLASDL S I G +I VD G
Sbjct: 228 GNTAAFLASDLSSGITGQIIYVDSG 252
>dbj|BAB05561.1| (AP001513) 3-oxoacyl-(acyl-carrier protein) reductase [Bacillus
halodurans]
Length = 247
Score = 91.3 bits (223), Expect = 1e-17
Identities = 71/260 (27%), Positives = 121/260 (46%), Gaps = 22/260 (8%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI-- 63
L K+A T +++GIG + + + GA V + + R EK + V Y+
Sbjct: 3 LRDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQGEKCVSYVSG 62
Query: 64 -VADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
V D + L ++V + N DI + G + + +M + W++ +++
Sbjct: 63 SVDDQLFIHSLFKSVVDKHN--RLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYT 120
Query: 123 LTKALVPAMERKGFGRIIYS---TSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
A +P MERK G+I+ T V +E N S + A+ GL R LA++ KG
Sbjct: 121 CCHAALPYMERKKQGKIVNVVSVTGVVGREAQTNYGAS---KGAIIGLTRLLARKYSEKG 177
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I++N I PG+I T+ + Q+ EE L+ + + +LG +E+ V +L
Sbjct: 178 ISINAIAPGMIETEMIKQVP-----------EEKLKNFLRFTNAKKLGSTKEVARNVLYL 226
Query: 240 ASDLGSYINGAMIPVDGGRL 259
+SDL Y+ ++ VDGG L
Sbjct: 227 SSDLSDYVTDTVLKVDGGFL 246
>emb|CAC17805.1| (AJ292535) SDR-like enzyme [Rhodococcus erythropolis]
Length = 246
Score = 91.3 bits (223), Expect = 1e-17
Identities = 77/257 (29%), Positives = 116/257 (44%), Gaps = 20/257 (7%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+A T GIG R L GA V++ +N ++ + + +
Sbjct: 5 LEGKVAVVTGGGSGIGAACVRQLCALGASVVVADIVFDNATLVAKEFGDRAVA----VEV 60
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTGG--PKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+ +++D ER V+ + + G DI + G P + E+W + + L A +
Sbjct: 61 DVARVEDAERMVETAVAHFGGLDIAVNNAGVGVPVKASVGDTGFEEWRRVLDVNLDGAFF 120
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+A + M RKG G ++ SV + + A+ GL +T A + GI V
Sbjct: 121 CMRAELRRM-RKG-GSVVNLASVMGAVAAEGSSSYVASKHALVGLTKTAALDYATAGIRV 178
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + G + T M A R+ E L A PLGRL +P+EI +VAFLAS
Sbjct: 179 NAVGAGFVDTPLM-------AGRD----PEWLAAVAASHPLGRLAQPDEIASVVAFLASS 227
Query: 243 LGSYINGAMIPVDGGRL 259
S++ GA IPVDGG L
Sbjct: 228 AASFVTGAFIPVDGGYL 244
>pir||H75014 3-oxoacyl-[acyl-carrier-protein] reductase PAB1085 - Pyrococcus
abyssi (strain Orsay) >gi|5459072|emb|CAB50558.1|
(AJ248288) 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE
[Pyrococcus abyssi]
Length = 240
Score = 90.9 bits (222), Expect = 1e-17
Identities = 75/261 (28%), Positives = 130/261 (49%), Gaps = 28/261 (10%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++L GK+A T +S+GIG +A LAK G +V+I R+ E + E++ + VE +
Sbjct: 1 MELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTEELCRQYGVETLLV 60
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAI 121
AD++ +++ VK+ + G DI + G K +E++ E+W+ + + L A
Sbjct: 61 KADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAF 120
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKE---PIPNIALSNVVRIAMAGLVRTLAKELGPK 178
+T+ ++ M++ G+I+ S+A K+ P+ A S IA L LA+ L P
Sbjct: 121 IVTQEVLRYMKK---GKIVNIASIAGKDGGTVGPHYAASKGGLIA---LTFNLARHLAP- 173
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
I VN + PG + TD + ++ K+ T G + +P E+ + V F
Sbjct: 174 NILVNAVAPGPVDTDMLSSEMKEMLKKLSLT--------------GDIAKPSEVAHAVIF 219
Query: 239 LASDLGSYINGAMIPVDGGRL 259
L + +I G +I V+GGRL
Sbjct: 220 LLEN--DHITGEVIDVNGGRL 238
>dbj|BAA94092.1| (AB040809) short chain alcohol dehydrogenase [Bacillus
thermoleovorans]
Length = 249
Score = 90.5 bits (221), Expect = 2e-17
Identities = 67/258 (25%), Positives = 114/258 (43%), Gaps = 22/258 (8%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ + K A T + GIG +AR AK GA+V+I+ R+ +N + +++ + E ++
Sbjct: 1 MSIEQKTAIVTGGANGIGKAIARAFAKQGANVVIIDRDIQNGEAFAAQLQSD-GFEAIFV 59
Query: 64 VADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
AD+ K+DD+ER V+E G D + G + E+++E+W++ + L A +
Sbjct: 60 AADVRKVDDIERFVQEAAGRFGRIDYLINNAGVSRWKSPYELTVEEWDDVLSTNLRSAFF 119
Query: 123 LTKALVPAMERKGFGRIIY---STSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
++ M R G I ST + E PN + + + LA
Sbjct: 120 ASREAAKYMRRNAKGGAIVNIASTRALMSE--PNSEAYAASKGGLVAMTHALAVSFADDR 177
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN I PG I T QL ++ P GR+G+P++I +L
Sbjct: 178 IRVNCISPGWIETGDYGQLRDIDHRQH---------------PAGRVGKPDDIARACLYL 222
Query: 240 ASDLGSYINGAMIPVDGG 257
+ +I G + +DGG
Sbjct: 223 CDEENDFITGVNLVIDGG 240
>sp|P73826|FAG2_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE 2 (3-KETOACYL- ACYL
CARRIER PROTEIN REDUCTASE 2) >gi|7431055|pir||S75021
3-ketoacyl-acyl carrier protein reductase -
Synechocystis sp. (strain PCC 6803)
>gi|1652966|dbj|BAA17883.1| (D90910) 3-ketoacyl-acyl
carrier protein reductase [Synechocystis sp.]
Length = 240
Score = 90.1 bits (220), Expect = 2e-17
Identities = 61/258 (23%), Positives = 118/258 (45%), Gaps = 24/258 (9%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
ML + L K+ T ++GIG + ++L + GA V + + N E
Sbjct: 1 MLSLGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFT-----------DLATDGGNTEA 49
Query: 61 HYIVADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
+VA++T ++ + E+ + +G + G K +F +++ DW+ + + L
Sbjct: 50 LGVVANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKG 109
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
Y K + M + G I+ +S++ + + + + G++++LA+E G
Sbjct: 110 VAYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYG 169
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
+ N + PG I T+ + + +D ++ K IP R G+PEEI + VAFL
Sbjct: 170 VRANAVAPGFIDTEMTLAIRED-----------IREKITKEIPFRRFGKPEEIAWAVAFL 218
Query: 240 ASDL-GSYINGAMIPVDG 256
S + SY+ G ++ V+G
Sbjct: 219 LSPVASSYVTGEVLRVNG 236
>pir||T36085 probable short chain dehydrogenase - Streptomyces coelicolor
>gi|4678628|emb|CAB41201.1| (AL049661) putative short
chain dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 255
Score = 90.1 bits (220), Expect = 2e-17
Identities = 78/264 (29%), Positives = 120/264 (44%), Gaps = 21/264 (7%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNV--E 59
+ DL+G+ A T + GIG +A LA+AGADVI+ + + A + + S + +
Sbjct: 1 MPFDLTGRRALVTGAGHGIGAAIALGLARAGADVIV--HHGHSADSAERVVADISALGRK 58
Query: 60 VHYIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTG---GPKPGYFMEMSMEDWEEAVKL 115
I AD+T + +ER V E + +G DI + G G P +M+ E + + +
Sbjct: 59 STAIAADVTDVTAVERLVDESVAFLGGLDIVVVNAGHLVGRVP--VADMTEEHFRSVIDV 116
Query: 116 LLYPAIYLTKALVPAMERKG-FGRIIYSTSVAIKE-PIPNIALSNVVRIAMAGLVRTLAK 173
L A +A +P + G GRII S A + P + + G + LAK
Sbjct: 117 NLVSAFRTCRAALPHVREAGRAGRIILMASQAAHDGGGPGATAYAAAKAGVIGFAKGLAK 176
Query: 174 ELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIG 233
E+G G+TVN + PG I D A T EA + +P+GR G +++
Sbjct: 177 EIGGAGVTVNALAPGYI---------GDTAFHGTFTAPEAQRGIVGKLPIGRAGTVDDVA 227
Query: 234 YLVAFLASDLGSYINGAMIPVDGG 257
+LAS YI GA + GG
Sbjct: 228 GTAVYLASGEAGYITGATFDIGGG 251
>gi|11498806 2-deoxy-D-gluconate 3-dehydrogenase (kduD) [Archaeoglobus fulgidus]
>gi|7431025|pir||F69400 2-deoxy-D-gluconate
3-dehydrogenase (kduD) homolog - Archaeoglobus fulgidus
>gi|2649386|gb|AAB90046.1| (AE001021)
2-deoxy-D-gluconate 3-dehydrogenase (kduD)
[Archaeoglobus fulgidus]
Length = 281
Score = 89.7 bits (219), Expect = 3e-17
Identities = 69/255 (27%), Positives = 118/255 (46%), Gaps = 12/255 (4%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV 64
DL+GK+A T ++ G+G +A LA G DV+++ R E L++ +E I E+ +
Sbjct: 32 DLTGKVAIVTGATGGLGGPIALGLADFGCDVVVVGRRLEVLEKLKESI-EKLGQRALAVK 90
Query: 65 ADLTKMDDLERTV-KELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+T +D+ V + ++ G DI G P E +EDW + + + +
Sbjct: 91 CDITSEEDVANLVNRTVEEFGRIDILVNCAGINIPKPAEEYPLEDWNKVMDANVTGVFLV 150
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIP-NIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+ + M ++ G+II +SV +P N + A+ + + LA E I V
Sbjct: 151 CREVGKVMVKQNGGKIINVSSVRSSYGMPKNYIAYCSSKAAVNMITKQLACEWAKYNILV 210
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N I P +I T + +D E + I LGR G P+++ V F ASD
Sbjct: 211 NAIAPTVIATPLTAHIMKD---------PELSKTMKSRILLGRWGYPDDLIGAVVFFASD 261
Query: 243 LGSYINGAMIPVDGG 257
+++ G ++ +DGG
Sbjct: 262 ASNFVTGQILYIDGG 276
>pir||T02175 hypothetical protein F14M4.4 - Arabidopsis thaliana
>gi|3522935|gb|AAC34217.1| (AC004411) putative alcohol
dehydrogenase [Arabidopsis thaliana]
Length = 257
Score = 89.7 bits (219), Expect = 3e-17
Identities = 73/260 (28%), Positives = 122/260 (46%), Gaps = 13/260 (5%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
M + L GK+A T + GIG R+ GA V+I+ EE + + ++ +
Sbjct: 1 MSGLRLDGKIAIITGGASGIGAEAVRLFTDHGAKVVIVDFQEELGQNVAVSVGKD---KA 57
Query: 61 HYIVADLTKMDDLERTVK-ELKNIGEPDIFFFSTGG-PKPGYFMEMSMEDWEEAVKLLLY 118
+ D+T ++E VK ++ G+ D+ F + G +PG F+++++E ++ + + +
Sbjct: 58 SFYRCDVTNEKEVENAVKFTVEKYGKLDVLFSNAGVMEQPGSFLDLNLEQFDRTMAVNVR 117
Query: 119 PAIYLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGP 177
A K AM KG G I+ +TSVA + P + A+ GLV++ LG
Sbjct: 118 GAAAFIKHAARAMVEKGTRGSIVCTTSVASEIGGPGPHAYTASKHALLGLVKSACGGLGK 177
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVA 237
GI VNG+ P + T R + + VEE A I G + + +
Sbjct: 178 YGIRVNGVAPYAVAT-----AINSRDEETVRMVEE--YSAATGILKGVVLKARHVAEAAL 230
Query: 238 FLASDLGSYINGAMIPVDGG 257
FLASD +Y++G + VDGG
Sbjct: 231 FLASDDSAYVSGQNLAVDGG 250
>sp|Q93761|YXEK_CAEEL HYPOTHETICAL OXIDOREDUCTASE F53C11.3 >gi|7504035|pir||T22556
hypothetical protein F53C11.3 - Caenorhabditis elegans
>gi|3877480|emb|CAB02118.1| (Z79756) predicted using
Genefinder~Similarity to Human 2,4-dienoyl-CoA reductase
(TR:G602703), contains similarity to Pfam domain:
PF00106 (short chain dehydrogenase), Score=150.9,
E-value=7.4e-42, N=1; PF00678 (Short chain
dehydrogenase/reductase C-t>
Length = 313
Score = 89.7 bits (219), Expect = 3e-17
Identities = 67/257 (26%), Positives = 121/257 (47%), Gaps = 11/257 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK+A T G+G +A A GA V I +R + L++ ++I+ +
Sbjct: 24 LNGKVALVTGGGTGLGKAIATTFAHLGASVAIAARRLDVLEKTADEIRSSTGGVCEPFQM 83
Query: 66 DLTKMDDLERTVKEL-KNIGE-PDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+ + + + K +G PDI + G +S + + ++L +++
Sbjct: 84 DVKDPAKVAKAFDAVEKKLGHTPDILINNAAGNFIMATERLSPNAYGTIIDIVLKGTLHV 143
Query: 124 TKALVP-AMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
T L +++K ++ T++ + P + S V + + + ++LA E G+
Sbjct: 144 TTELGRRCIQQKRGASVLSITTLYAQSGAPFVVPSAVSKAGVENMTKSLASEWAKHGLRF 203
Query: 183 NGIMPGIIRTDRMI-QLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
N I PG I T+ +L K G ++ + +P+GRLG PEEI L AF++S
Sbjct: 204 NAIAPGPIPTEGAFGRLFAGELKDSGDAMKAS-------VPVGRLGHPEEIANLAAFMSS 256
Query: 242 DLGSYINGAMIPVDGGR 258
D S++NGA+I DGG+
Sbjct: 257 DFMSWMNGAIIDFDGGQ 273
>gi|10955079 yhg [Agrobacterium tumefaciens] >gi|8572700|gb|AAF77146.1|
(AF242881) yhg [Agrobacterium tumefaciens]
Length = 258
Score = 89.7 bits (219), Expect = 3e-17
Identities = 72/258 (27%), Positives = 113/258 (42%), Gaps = 15/258 (5%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHY 62
K L GK+A T ++GIG A +AGA + + +R EE + +V +
Sbjct: 9 KFRLDGKVALITGGTRGIGLATAYAFGEAGAKLYLSARREEYEDAGAILT---AGYDVTF 65
Query: 63 IVADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
ADL + VK + + G DI + G G + + W + + +
Sbjct: 66 YPADLKTREAACALVKRVADDAGRLDILINNAGIANGGDTPLFTEQQWRDVIATNVETVF 125
Query: 122 YLTKALVPAMERKGFGRIIYSTSVA-IKEPIP-NIALSNVVRIAMAGLVRTLAKELGPKG 179
+ ++A +P M G G I+ S++ I IP N N + A+ + ++LA EL
Sbjct: 126 WCSQAAIPVMREGGRGAIVNVGSMSGIVSNIPQNQVAYNSSKAAVHMMTKSLASELALDN 185
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFL 239
I VN + PG I TD R G + + P+ R G P+EI + FL
Sbjct: 186 IRVNAVAPGYIDTDM---------SRGGMVHPVRGPIWLEMTPMKRFGRPDEIATAILFL 236
Query: 240 ASDLGSYINGAMIPVDGG 257
AS+ SY+ G ++ VDGG
Sbjct: 237 ASEASSYVTGDILVVDGG 254
>sp|Q05528|KDUD_ERWCH 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE (2-KETO-3-DEOXYGLUCONATE
OXIDOREDUCTASE) >gi|78265|pir||S17711 probable
dehydrogenase (EC 1.1.1.-) kduD - Erwinia chrysanthemi
>gi|48986|emb|CAA43989.1| (X62073)
2-keto-3-deoxygluconate oxydoreductase [Erwinia
chrysanthemi]
Length = 253
Score = 89.3 bits (218), Expect = 4e-17
Identities = 73/264 (27%), Positives = 127/264 (47%), Gaps = 28/264 (10%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI- 63
+L GK+A T G+G G+A LA+AG D++ + N+ +E I++ + V ++
Sbjct: 7 NLQGKVALITGCDTGLGQGMAVGLAEAGCDIVGV-----NIVEPKETIEKVTAVGRRFLS 61
Query: 64 -VADLTKMDDLERTV-KELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
AD++ + V K + G+ DI + G + +E S ++W++ + L +
Sbjct: 62 LTADMSDISGHAALVEKAVAEFGKVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVF 121
Query: 122 YLTKALVPAMERKGFG-RIIYSTSVAIKE---PIPNIALSNVVRIAMAGLVRTLAKELGP 177
++++ + ++G G +II S+ + P+P+ S + + G+ R +A E
Sbjct: 122 FMSQTVARQFIKQGHGGKIINIASMLSFQGGIPVPSYTAS---KKRVMGITRIVANEWAK 178
Query: 178 KGITVNGIMPGIIRTDRM--IQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYL 235
I VN I PG + T+ ++ QDR+K E IP GR G P+++
Sbjct: 179 HNINVNAIAPGYMATNNTQHVRADQDRSK-----------EILDRIPAGRWGLPQDLQGP 227
Query: 236 VAFLASDLGSYINGAMIPVDGGRL 259
FLAS Y+NG I VDGG L
Sbjct: 228 AVFLASSASDYVNGYTIAVDGGWL 251
>pdb|1HDC|A Chain A, 3-Alpha, 20-Beta-Hydroxysteroid Dehydrogenase
(E.C.1.1.1.53) Complexed With Carbenoxolone
>gi|999596|pdb|1HDC|B Chain B, 3-Alpha,
20-Beta-Hydroxysteroid Dehydrogenase (E.C.1.1.1.53)
Complexed With Carbenoxolone >gi|999597|pdb|1HDC|C Chain
C, 3-Alpha, 20-Beta-Hydroxysteroid Dehydrogenase
(E.C.1.1.1.53) Complexed With Carbenoxolone
>gi|999598|pdb|1HDC|D Chain D, 3-Alpha,
20-Beta-Hydroxysteroid Dehydrogenase (E.C.1.1.1.53)
Complexed With Carbenoxolone >gi|640224|pdb|2HSD|A Chain
A, 3 Alpha, 20 Beta-Hydroxysteroid Dehydrogenase (Holo
Form) (E.C.1.1.1.53) >gi|640225|pdb|2HSD|B Chain B, 3
Alpha, 20 Beta-Hydroxysteroid Dehydrogenase (Holo Form)
(E.C.1.1.1.53) >gi|640226|pdb|2HSD|C Chain C, 3 Alpha,
20 Beta-Hydroxysteroid Dehydrogenase (Holo Form)
(E.C.1.1.1.53) >gi|640227|pdb|2HSD|D Chain D, 3 Alpha,
20 Beta-Hydroxysteroid Dehydrogenase (Holo Form)
(E.C.1.1.1.53)
Length = 253
Score = 89.3 bits (218), Expect = 4e-17
Identities = 79/256 (30%), Positives = 116/256 (44%), Gaps = 20/256 (7%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAGADVIILS-RNEENLKRAREKIKEESNVEVHYI 63
DLSGK T ++G+G AR AGA V++ +EE ARE Y
Sbjct: 2 DLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATAREL-----GDAARYQ 56
Query: 64 VADLTKMDDLERTVKELKN-IGEPDIFFFSTGGPKPGYFMEM-SMEDWEEAVKLLLYPAI 121
D+T +D +R V + G D + G G F+E S+E + + V++ L
Sbjct: 57 HLDVTIEEDWQRVVAYAREEFGSVD-GLVNNAGISTGMFLETESVERFRKVVEINLTGVF 115
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
K ++PAM+ G G I+ +S A + + + + GL + A ELG I
Sbjct: 116 IGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIR 175
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG+ T + + R+G+ Y P+GR+GEP EI V L S
Sbjct: 176 VNSVHPGMTYTP----MTAETGIRQGEG------NYPNT-PMGRVGEPGEIAGAVVKLLS 224
Query: 242 DLGSYINGAMIPVDGG 257
D SY+ GA + VDGG
Sbjct: 225 DTSSYVTGAELAVDGG 240
>pir||B65059 probable dehydrogenase (EC 1.1.1.-) b2774 - Escherichia coli
(strain K-12) >gi|1789135|gb|AAC75816.1| (AE000361)
putative oxidoreductase [Escherichia coli K12]
Length = 286
Score = 89.3 bits (218), Expect = 4e-17
Identities = 75/255 (29%), Positives = 114/255 (44%), Gaps = 12/255 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK A T + G+G A LAKAGA++ I S ++N +E I E+ VEV ++
Sbjct: 41 LKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDN-GETKEMI-EKQGVEVDFMQV 98
Query: 66 DLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
+T ++ + + G DI + G K ++ DW+ + + L A L+
Sbjct: 99 GITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELS 158
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
M + G+II S+ + + A+AG + ELG I VNG
Sbjct: 159 YEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNG 218
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
I PG TD I LA ++ E Q IP R G+ +++ FLAS
Sbjct: 219 IAPGYYATD--ITLAT-------RSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPAS 269
Query: 245 SYINGAMIPVDGGRL 259
+Y+NG ++ VDGG L
Sbjct: 270 NYVNGHLLVVDGGYL 284
>pir||S69225 nogalamycin polyketide ketoreductase (EC 1.1.1.-) snoaD
[similarity] - Streptomyces nogalater
>gi|2916808|emb|CAA12013.1| (AJ224512) SnoaD
[Streptomyces nogalater]
Length = 262
Score = 89.3 bits (218), Expect = 4e-17
Identities = 67/257 (26%), Positives = 117/257 (45%), Gaps = 5/257 (1%)
Query: 5 DLSGKLAFTTASSKGIGFGVARVLAKAG-ADVIILSRNEENLKRAREKIKEESNVEVHYI 63
D G++A T + GIG V + LA G A + +R+++ + E++++E +EV
Sbjct: 3 DTDGRVAVVTGGTSGIGLAVVKALAATGYACRSLCARSQDAVDSTVEELRDEK-LEVDGR 61
Query: 64 VADLTKMDDLERTVK-ELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D+ DD+ + + G D+ + G G ++ E W + ++ L
Sbjct: 62 SCDVRSTDDVREFIGFATRRFGGVDVLVNNAGRNGGGPTARITDELWLDVIETNLTSVFR 121
Query: 123 LTKALVPA--MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+T+ ++ M G GRII S K+ + A + + + G + L EL GI
Sbjct: 122 VTREVLTTGGMLAAGRGRIINIASTGGKQGVVLGAPYSASKHGVVGFTKALGLELAKSGI 181
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + PG + T ++ + A+ + E L+ + IPLGR +PEE+ LV +L
Sbjct: 182 TVNAVCPGYVETPMGERVGRGYAEVWDTSEEAVLERFQAKIPLGRYAQPEEVAGLVTYLT 241
Query: 241 SDLGSYINGAMIPVDGG 257
+ I + V GG
Sbjct: 242 TPTADSITAQALNVCGG 258
>sp|P76633|YGCW_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN CYSJ-ENO INTERGENIC REGION
Length = 261
Score = 89.3 bits (218), Expect = 4e-17
Identities = 75/255 (29%), Positives = 114/255 (44%), Gaps = 12/255 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK A T + G+G A LAKAGA++ I S ++N +E I E+ VEV ++
Sbjct: 16 LKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDN-GETKEMI-EKQGVEVDFMQV 73
Query: 66 DLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
+T ++ + + G DI + G K ++ DW+ + + L A L+
Sbjct: 74 GITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELS 133
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
M + G+II S+ + + A+AG + ELG I VNG
Sbjct: 134 YEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNG 193
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
I PG TD I LA ++ E Q IP R G+ +++ FLAS
Sbjct: 194 IAPGYYATD--ITLAT-------RSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPAS 244
Query: 245 SYINGAMIPVDGGRL 259
+Y+NG ++ VDGG L
Sbjct: 245 NYVNGHLLVVDGGYL 259
>gb|AAD32718.1| (AF127374) MitF [Streptomyces lavendulae]
Length = 257
Score = 89.3 bits (218), Expect = 4e-17
Identities = 74/257 (28%), Positives = 122/257 (46%), Gaps = 15/257 (5%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVH 61
++ SG++ + +S IG A LA GA V+ E+ +++ RE+++ + V
Sbjct: 11 RLGQSGRVVVVSGASGQIGGACALELAALGATVVAGYHSGEQAIRKLREQVEGQGGTLVP 70
Query: 62 YIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ ADL++ + + V ++ G D + G M E+ +++ L +
Sbjct: 71 -VAADLSEPEGADALVAAAVERFGRVDGCVAAAGLRTRRLAMATDARSLEKLLRVNLAGS 129
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+ L KA + M R +GRI+ S A +P + + A+ ++A E+G GI
Sbjct: 130 VGLAKACLKPMMRARYGRIVLFGSRAGTSGLPGHSAYAATKGALQPWAASVAGEVGKHGI 189
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + PG IR + M D ++ E V + I GRLGEPEE+ V+FL
Sbjct: 190 TVNVVAPGAIRAEVM-----DFSEAERDLVLQF-------IGAGRLGEPEEVAAAVSFLL 237
Query: 241 SDLGSYINGAMIPVDGG 257
S SY+NG + VDGG
Sbjct: 238 SPSASYVNGNTLVVDGG 254
>gb|AAF89839.1|AF173961_5 (AF173961) BbsD [Thauera aromatica]
Length = 248
Score = 89.3 bits (218), Expect = 4e-17
Identities = 71/254 (27%), Positives = 115/254 (44%), Gaps = 14/254 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
+ ++A T S+ G+G A A+ GA V+I + E ++ ++ + V VA
Sbjct: 3 IQNRVALITGSASGMGKQTALRFAEQGAAVVINDIDAEKVRATVDEFSARGH-RVLGAVA 61
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+ ++ VK+ + G DI + G + G ++S DW+ + + L T
Sbjct: 62 DIGNKAAVDGMVKQTIDAFGRIDILVNNAGMERAGALRKLSEADWDVTINVNLKGTFLCT 121
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
+A+ M GRI+ S A S+ + + G+ R LA ELG GITVN
Sbjct: 122 QAVHGHMVENKHGRIVNIASRAWLGGAGQTPYSSA-KAGVVGMTRALAIELGRAGITVNC 180
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
+ PG+I T +L E+ Q P G+LGEP++I + FLA D
Sbjct: 181 VAPGLIHTPMWDELP-----------EKDQQFLLSRQPTGKLGEPDDIANTLLFLADDDS 229
Query: 245 SYINGAMIPVDGGR 258
++ G ++ V GGR
Sbjct: 230 GFVTGQVLYVCGGR 243
>gb|AAF75282.1|AF271714_1 (AF271714) beta-hydroxybutyrate dehydrogenase [Pseudomonas sp.
GM101]
Length = 255
Score = 88.9 bits (217), Expect = 5e-17
Identities = 74/256 (28%), Positives = 111/256 (42%), Gaps = 6/256 (2%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK A T S+ GIG G+A VLA+ GA VI+ + + A E++ V Y A
Sbjct: 2 LNGKTALITGSTSGIGLGIAEVLARNGASVIL--NGFGDWQAAAEQLARHEG-RVGYHAA 58
Query: 66 DLTKMDDLERTVK-ELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
DL +E + G DI + G + E W+ + L L + T
Sbjct: 59 DLADPAQIEALFDYARREFGRVDILVNNAGIQHVAPLQDFPAERWDAILALNLSAVFHCT 118
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
+ +P M + +GRII SV A + + GL + +A E G+T N
Sbjct: 119 RLALPDMRAQDWGRIINIASVHGSIGSLGKAAYVAAKHGVLGLTKVVALETALSGVTCNA 178
Query: 185 IMPGIIRTDRMIQLAQDRAKREGKTVEEALQE-YAKPIPLGRLGEPEEIGYLVAFLASDL 243
I PG + T ++Q D G++ E+A A+ P P+++G L FL S
Sbjct: 179 ICPGWVLTP-LVQRQIDARIAAGESPEQARTALLAEKQPSQAFVTPQQLGELALFLCSSA 237
Query: 244 GSYINGAMIPVDGGRL 259
+ GA +DGG L
Sbjct: 238 AQQVRGAAWNIDGGWL 253
>dbj|BAB05863.1| (AP001514) 2,4-dienoyl-CoA reductase (NADPH) [Bacillus halodurans]
Length = 257
Score = 88.5 bits (216), Expect = 7e-17
Identities = 71/257 (27%), Positives = 119/257 (45%), Gaps = 14/257 (5%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
+ + T S G+G +A A GA+V+I R++E L+ A+ ++ ++S V +
Sbjct: 1 MKNQTIIVTGGSNGMGKAMAARFASLGANVVITGRDQERLETAKSEVAQDSG-RVLTVQM 59
Query: 66 DLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D+ DD+ER VK+ L G D + G ++S+ W+ + ++L + T
Sbjct: 60 DVRNPDDVERMVKDTLSEFGAIDGLVNNAAGNFLCAAEDLSLNGWKSVIDIVLNGTWHCT 119
Query: 125 KALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK-GITV 182
+A+ + G G I+ + + S + + + RTLA E G K GI +
Sbjct: 120 QAVGKEWIKDGRKGHILNMVATYAWTAGAGVVHSASAKAGVLAMTRTLAVEWGTKYGIRL 179
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYA-KPIPLGRLGEPEEIGYLVAFLAS 241
N I PG I + E + E Q+ + +PL R G EEI L A+L S
Sbjct: 180 NAIAPGPI---------EGTGGAEKLILNETFQKAVLQTVPLKRFGTLEEIAGLAAYLFS 230
Query: 242 DLGSYINGAMIPVDGGR 258
+ +Y+NG I +DGG+
Sbjct: 231 EEATYMNGECISLDGGQ 247
>sp|O34717|YKUF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN CHEV-MOBA INTERGENIC REGION
>gi|7431064|pir||C69865 glucose 1-dehydrogenase homolog
ykuF - Bacillus subtilis >gi|2632227|emb|CAA10869.1|
(AJ222587) YkuF protein [Bacillus subtilis]
>gi|2633777|emb|CAB13279.1| (Z99111) similar to glucose
1-dehydrogenase [Bacillus subtilis]
Length = 254
Score = 88.2 bits (215), Expect = 9e-17
Identities = 74/254 (29%), Positives = 116/254 (45%), Gaps = 14/254 (5%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K T S G+G +A+ A+ G V++ RN E L+ +++I+ +V D+
Sbjct: 4 KAVIITGGSSGMGKAMAKKQAELGWHVMVTGRNHEALEETKKEIQTFEG-QVACFQMDVR 62
Query: 69 KMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKAL 127
+KE +K G D + G +++ W+ ++++L + ++A
Sbjct: 63 SDSAASDMIKEAVKAFGRLDALINNAAGNFICPAEKLTPNGWKAVIEIVLNGTFFCSQAA 122
Query: 128 VPA-MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK-GITVNGI 185
+++K G I+ + + S + + L RTLA E G K GI N I
Sbjct: 123 ARHWIDQKQQGVILNMAATYAWGAGAGVVHSAAAKAGVLSLTRTLAVEWGSKYGIRTNAI 182
Query: 186 MPGII-RTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLG 244
PG I RT +L + E+A+ +PLGRLG PEEI L AFL SD
Sbjct: 183 APGPIERTGGAEKLFES---------EKAMARTMNSVPLGRLGTPEEIAALAAFLLSDEA 233
Query: 245 SYINGAMIPVDGGR 258
SYING I +DGG+
Sbjct: 234 SYINGDCITMDGGQ 247
>dbj|BAA95121.1| (AB042262) levodione reductase [Corynebacterium aquaticum]
Length = 267
Score = 88.2 bits (215), Expect = 9e-17
Identities = 70/253 (27%), Positives = 119/253 (46%), Gaps = 6/253 (2%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEES-NVEVHYIVADL 67
++ T G+G A LA GA + ++ + E L+ ++ + E + + EV VAD+
Sbjct: 14 RVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADV 73
Query: 68 TKMDDLERTVKEL-KNIGEPDIFFFSTG-GPKPGYFMEMSMEDWEEAVKLLLYPAIYLTK 125
+ +E V + G D FF + G K + ++++ V + L +
Sbjct: 74 SDEAQVEAYVTATTERFGRIDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFLGLE 133
Query: 126 ALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGI 185
++ M +G G ++ + SV I N + + + GL R A E G GI +N I
Sbjct: 134 KVLKIMREQGSGMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNSAVEYGRYGIRINAI 193
Query: 186 MPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGS 245
PG I T M++ + + E +A +E+ + P R GE EI +VAFL SD S
Sbjct: 194 APGAIWTP-MVENSMKQLDPENP--RKAAEEFIQVNPSKRYGEAPEIAAVVAFLLSDDAS 250
Query: 246 YINGAMIPVDGGR 258
Y+N ++P+DGG+
Sbjct: 251 YVNATVVPIDGGQ 263
>pir||D70707 hypothetical protein Rv0769 - Mycobacterium tuberculosis (strain
H37RV) >gi|1550647|emb|CAB02381.1| (Z80226) hypothetical
protein Rv0769 [Mycobacterium tuberculosis]
Length = 248
Score = 87.8 bits (214), Expect = 1e-16
Identities = 67/258 (25%), Positives = 123/258 (46%), Gaps = 24/258 (9%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K+A T +++GIG A+ LA+ GA V++ N + ++I + +H + D++
Sbjct: 5 KVAIVTGAAQGIGQAYAQALAREGASVVVADINADGAAAVAKQIVADGGTAIH-VPVDVS 63
Query: 69 KMDDLERTV-KELKNIGEPDIFFFST---GGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D + V + + G D + GG K + + ++ +++ + + + T
Sbjct: 64 DEDSAKAMVDRAVGAFGGIDYLVNNAAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCT 123
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSN---VVRIAMAGLVRTLAKELGPKGIT 181
+A+ M ++G G I+ +S A SN + ++ + GL + LA+ELG I
Sbjct: 124 RAVYKHMAKRGGGAIVNQSSTAAW------LYSNFYGLAKVGVNGLTQQLARELGGMKIR 177
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
+N I PG I T+ + T E ++ + IPL R+G PE++ + FL S
Sbjct: 178 INAIAPGPIDTEATRTV----------TPAELVKNMVQTIPLSRMGTPEDLVGMCLFLLS 227
Query: 242 DLGSYINGAMIPVDGGRL 259
D S+I G + VDGG++
Sbjct: 228 DSASWITGQIFNVDGGQI 245
>gb|AAC95201.1| (AC004561) putative tropinone reductase [Arabidopsis thaliana]
Length = 268
Score = 87.4 bits (213), Expect = 2e-16
Identities = 73/257 (28%), Positives = 114/257 (43%), Gaps = 12/257 (4%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHY 62
K L G A T SKG+G V LA GA V +R+E L+ + + + + ++V
Sbjct: 13 KWSLEGMTALVTGGSKGLGKAVVEELAMLGARVHTCARDETQLQESLREWQAKG-LQVTT 71
Query: 63 IVADLTKMDDLERTVKELKNI--GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
V D++ D E+ ++ + ++ G+ I + G E + E++ + L
Sbjct: 72 SVCDVSSRDQREKLMETVSSLFQGKLSILVPNVGIGVLKPTTECTAEEFSFIIATNLEST 131
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+ ++ P ++ G G I+ +SVA + N ++ + AM L R LA E I
Sbjct: 132 FHFSQLAHPLLKASGSGNIVLMSSVAGVVNLGNTSIYGATKGAMNQLARNLACEWASDNI 191
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
N + P I T D K V+E ++ PL R+GE E+ LVAFL
Sbjct: 192 RANSVCPWFITTPSTKDFLGD------KDVKEKVESVT---PLRRVGEANEVSSLVAFLC 242
Query: 241 SDLGSYINGAMIPVDGG 257
SYI G I VDGG
Sbjct: 243 LPAASYITGQTICVDGG 259
>emb|CAB60183.1| (AL132824) reductase [Streptomyces coelicolor]
Length = 262
Score = 87.4 bits (213), Expect = 2e-16
Identities = 76/261 (29%), Positives = 119/261 (45%), Gaps = 18/261 (6%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK A T S+GIG G+A LA GA V + + E R + S + I A
Sbjct: 12 LEGKTALVTGGSRGIGRGIALRLAADGALVAVHYGSSEAAARETVETIRSSGGQALAIRA 71
Query: 66 DLTKMDD-------LERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLY 118
+L + D + + E E DI + G G E++ E ++ V + +
Sbjct: 72 ELGVVGDAAALYAAFDAGMGEFGVPPEFDILVNNAGVSGSGRITEVTEEVFDRLVAVNVR 131
Query: 119 PAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPK 178
++L + + + R G GRII +S A + P + + A+ L LA++LG +
Sbjct: 132 APLFLVQHGLKRL-RDG-GRIINISSAATRRAFPESIGYAMTKGAVDTLTLALARQLGER 189
Query: 179 GITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
GITVN + PG + TD + +R+ AL Y+ R+G P++I +VAF
Sbjct: 190 GITVNAVAPGFVETD------MNARRRQTPEAAAALAAYS---VFNRIGRPDDIADVVAF 240
Query: 239 LASDLGSYINGAMIPVDGGRL 259
LASD +I G + GG +
Sbjct: 241 LASDDSRWITGQYVDATGGTI 261
>pir||B83332 cis-1,2-dihydroxycyclohexa-3,4-diene carboxylate dehydrogenase
PA2515 [imported] - Pseudomonas aeruginosa (strain
PAO1) >gi|9948569|gb|AAG05903.1|AE004678_9 (AE004678)
cis-1,2-dihydroxycyclohexa-3,4-diene carboxylate
dehydrogenase [Pseudomonas aeruginosa]
Length = 253
Score = 87.0 bits (212), Expect = 2e-16
Identities = 74/259 (28%), Positives = 125/259 (47%), Gaps = 22/259 (8%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLT 68
K+A + +++GIG GVAR L + GA V+ + R+E + E + + ADL
Sbjct: 8 KVALVSGAAQGIGLGVARRLLEEGARVVAVDRSE--------LVHELAGDACLCLTADLE 59
Query: 69 KMDDLERTVKE-LKNIGEPDIFFFSTGGP---KPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
+ + +R ++ L+ G DI + GG KP + + ++ E ++ L P ++
Sbjct: 60 RYAECQRVLERTLERFGRLDILVNNVGGTLWAKP--YQHYAEDEIEAELRRSLLPTLWCC 117
Query: 125 KALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNG 184
+A +PAM +G G I+ +SVA + N + + L LA E +GI VN
Sbjct: 118 RAALPAMLGQGSGAIVNVSSVATRGV--NRVPYGAAKGGVNALTACLAFETADQGIRVNA 175
Query: 185 IMPGIIRTD----RMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
+ PG TD R+ + A +++ E + + +++ + R G +E + FLA
Sbjct: 176 VAPG--GTDAPPRRIPRNAAAQSEEERRWYRQIVEQTLDSSLMKRYGSIDEQVAAILFLA 233
Query: 241 SDLGSYINGAMIPVDGGRL 259
SD SYI G +PV GG L
Sbjct: 234 SDEASYITGVTLPVAGGDL 252
>pir||B69802 glucose 1-dehydrogenase homolog yfhR - Bacillus subtilis
>gi|1673388|emb|CAB04808.1| (Z82044) unidentfied
dehydrogenase [Bacillus subtilis]
>gi|2633188|emb|CAB12693.1| (Z99108) alternate gene
name: ygaA~similar to glucose 1-dehydrogenase [Bacillus
subtilis] >gi|2804548|dbj|BAA24484.1| (D85082) YfhR
[Bacillus subtilis]
Length = 250
Score = 86.6 bits (211), Expect = 3e-16
Identities = 68/252 (26%), Positives = 117/252 (45%), Gaps = 12/252 (4%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVEVHYIVADL 67
K A T SS+G+G A LA+ G +++I +R+++ E+I E+ V+V + A++
Sbjct: 5 KCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEI-EKLGVKVLVVKANV 63
Query: 68 TKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKA 126
+ ++ +++ + G D+F + ME+ W+ + + ++ +
Sbjct: 64 GQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQE 123
Query: 127 LVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
ME+ G G I+ +S+ + N V + A+ L R LA EL PK I VN +
Sbjct: 124 AAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVS 183
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
G I TD A + E+ L++ + P GR+ E +++ V FL S
Sbjct: 184 GGAIDTD---------ALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADM 234
Query: 247 INGAMIPVDGGR 258
I G I VDGGR
Sbjct: 235 IRGQTIIVDGGR 246
>gb|AAC69902.1| (AF100956) KE6a [Mus musculus]
Length = 266
Score = 86.6 bits (211), Expect = 3e-16
Identities = 78/273 (28%), Positives = 125/273 (45%), Gaps = 31/273 (11%)
Query: 3 KIDLSGKLAFTTAS---SKGIGFGVARV----LAKAGADVIILSRN----EENLKRAREK 51
++ L LA T S S+G G G+ R LA GA V + ++ ++
Sbjct: 4 QLRLRSALALVTGSGVPSQGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSP 63
Query: 52 IKEESNVEVHYIV--ADLTKMDDLERTVKELKNIGE--PDIFFFSTGGPKPGYFMEMSME 107
E+ + AD+++ R ++E++ P + G + + + MS E
Sbjct: 64 GSEDGAPRGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEE 123
Query: 108 DWEEAVKLLLYPAIYLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVV--RIAM 164
DW+ + + L +T+A A+ G G II +S+ K + NI +N + +
Sbjct: 124 DWDRVIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGK--VGNIGQTNYASSKAGV 181
Query: 165 AGLVRTLAKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLG 224
GL +T A+ELG GI N ++PG I T M Q K E+ + IPLG
Sbjct: 182 IGLTQTAARELGRHGIRCNSVLPGFIATP-MTQ----------KMPEKVKDKVTAMIPLG 230
Query: 225 RLGEPEEIGYLVAFLASDLGSYINGAMIPVDGG 257
+G+PE++ +VAFLAS+ YI GA + V GG
Sbjct: 231 HMGDPEDVADVVAFLASEDSGYITGASVEVSGG 263
>emb|CAC18176.1| (AL451014) probable NADPH-dependent beta-ketoacyl reductase (rhlG)
[Neurospora crassa]
Length = 286
Score = 86.6 bits (211), Expect = 3e-16
Identities = 75/271 (27%), Positives = 117/271 (42%), Gaps = 29/271 (10%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEE-----SNVEV 60
+ GK+A T S+G+G A L +AGA + +S + + + K +
Sbjct: 15 VKGKVAVVTGGSRGLGLSAASALLQAGASKVFISSRKASACDSAVKTLNALPGLAPGAKA 74
Query: 61 HYIVADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYP 119
I AD + ++ V E+ K+ DI + G F E + + + L +
Sbjct: 75 ISIPADAATLSGVQHLVSEVAKHTDHVDILLANAGATWGAPFDEHPDSAFAKVMDLNVRG 134
Query: 120 AIYLTKALVPAMERKGF----GRIIYSTSVAI-------KEPIPNIALSNVVRIAMAGLV 168
+ P +++K R+I + SVA K+ + S + A+ L
Sbjct: 135 VFNTIREFAPLLQKKASVEDPSRVIITASVAGLGIGTIGKQGTYGYSAS---KAAVIHLG 191
Query: 169 RTLAKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGE 228
R LA ELGP+GITVN I PG T L +E A P+ RLG
Sbjct: 192 RNLAVELGPRGITVNSICPGFFPTKMSNGLLDMSGGKES---------IAAANPMKRLGR 242
Query: 229 PEEIGYLVAFLASDLGSYINGAMIPVDGGRL 259
PE+I +V +LAS G+++NGA I +DGG +
Sbjct: 243 PEDIAGVVVYLASRAGAHVNGATIAIDGGAM 273
>gb|AAC44807.1| (U32622) toluenesulfonate zinc-independent alcohol dehydrogenase
[Comamonas testosteroni]
Length = 252
Score = 85.8 bits (209), Expect = 5e-16
Identities = 66/262 (25%), Positives = 118/262 (44%), Gaps = 19/262 (7%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
++L+ ++A T + G G +AR L++AGA V++ N E +R ++ + +
Sbjct: 1 MNLNKQVAIVTGGASGFGAAIARRLSQAGAAVLVADLNAEGAQRMATELNAAGGRALG-M 59
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGP---KPGYFMEMSMEDWEEAVKLLLYP 119
D++K D V + +G I + G KP + ++ ++++ ++ L
Sbjct: 60 ACDVSKEADYRAVVDAAIAQLGGLHIVVNNAGTTHRNKPA--LAVTEDEFDRVYRVNLKS 117
Query: 120 AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
+ + +P ++G G ++ S P P + + + AM L + LA E G
Sbjct: 118 VYWSAQCALPHFAQQGHGVMVNVASTTGVRPGPGLTWYSGSKAAMINLTKGLALEFARSG 177
Query: 180 ITVNGIMPGIIRTDRMIQ---LAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLV 236
+ +N + P I T M + A RE + IPLGR P+++ V
Sbjct: 178 VRINAVNPMIGETPMMADFMGMEDTPANRE---------RFLSRIPLGRFTRPDDVASAV 228
Query: 237 AFLASDLGSYINGAMIPVDGGR 258
AFLASD S++ G + VDGGR
Sbjct: 229 AFLASDDASFLTGVCLDVDGGR 250
>pir||B71923 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) -
Helicobacter pylori (strain J99)
>gi|4155047|gb|AAD06084.1| (AE001484) ACETYL-COENZYME A
CARBOXYLASE SUBUNIT A [Helicobacter pylori J99]
Length = 247
Score = 85.8 bits (209), Expect = 5e-16
Identities = 66/255 (25%), Positives = 107/255 (41%), Gaps = 12/255 (4%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ +GK T +SKGIG +A+ LA G V I R+ + A + EE + I
Sbjct: 1 MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNGLEEKGYKAAVI 60
Query: 64 VADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D D ++ + ++ G + G + ++M ED+ ++ L A
Sbjct: 61 KFDAASESDFVEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIENNLTSAFI 120
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+ + M + FG ++ S+ + + + M + ++ A E + I
Sbjct: 121 GCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF 180
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I TD L +E +Y K IPL RLG +E+ VAFL SD
Sbjct: 181 NSVTPGFIETDMNANLK-----------DELKADYVKNIPLNRLGSAKEVAEAVAFLLSD 229
Query: 243 LGSYINGAMIPVDGG 257
SYI G + V+GG
Sbjct: 230 HSSYITGETLKVNGG 244
>pir||H75330 enoyl-acyl carrier protein reductase - Deinococcus radiodurans
(strain R1) >gi|6459755|gb|AAF11519.1|AE002035_2
(AE002035) enoyl-acyl carrier protein reductase
[Deinococcus radiodurans]
Length = 264
Score = 85.8 bits (209), Expect = 5e-16
Identities = 81/262 (30%), Positives = 118/262 (44%), Gaps = 22/262 (8%)
Query: 4 IDLSGKLAFT--TASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKI-KEESNVEV 60
IDLSGK A A+++ +G+ +A L +AG V S E LK EK+ K+ N +
Sbjct: 5 IDLSGKTALVMGVANARSLGWAIAEQLLQAGCRVGF-SYQGERLKGELEKLTKDWPNTWI 63
Query: 61 HYIVADLTKMDDLERTVKELKN-IGEPDIFFFSTG-GPKP---GYFMEMSMEDWEEAVKL 115
AD T +D++ +K+ E + S G P+ G F++ + +DW A+ +
Sbjct: 64 QQ--ADATSEEDMDALFARVKDEFSELHLLVHSIGFAPRTAMDGRFIDTTADDWNTALNV 121
Query: 116 LLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKEL 175
Y + + P M G II T A ++ +P + V + A+ R LA +L
Sbjct: 122 SAYTLVAAARRAEPLMPDGG--SIISLTYHASQQVVPRYNVMGVAKAALEAATRYLAADL 179
Query: 176 GPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYL 235
G + I VN I G +RT +A GK + A GR EE+G L
Sbjct: 180 GEREIRVNTISAGPMRT-----IAARSIPHFGKLYNKGAMNAA----FGRNATSEEVGKL 230
Query: 236 VAFLASDLGSYINGAMIPVDGG 257
FL SDL S I G I VD G
Sbjct: 231 ALFLLSDLSSGITGQTIYVDAG 252
>gb|AAC53573.1| (U34072) steroid dehydrogenase [Mus musculus]
Length = 260
Score = 85.4 bits (208), Expect = 6e-16
Identities = 75/267 (28%), Positives = 123/267 (45%), Gaps = 25/267 (9%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRN----EENLKRAREKIKEESNV 58
++ L LA T + GIG ++ LA GA V + ++ ++ E+
Sbjct: 4 QLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAP 63
Query: 59 EVHYIV--ADLTKMDDLERTVKELKNIGE--PDIFFFSTGGPKPGYFMEMSMEDWEEAVK 114
+ AD+++ R ++E++ P + G + + + MS EDW+ +
Sbjct: 64 RGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIA 123
Query: 115 LLLYPAIYLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVV--RIAMAGLVRTL 171
+ L +T+A A+ G G II +S+ K + NI +N + + GL +T
Sbjct: 124 VNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGK--VGNIGQTNYASSKAGVIGLTQTA 181
Query: 172 AKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPE- 230
A+ELG GI N ++PG I T M Q K E+ + IPLG +G+PE
Sbjct: 182 ARELGRHGIRCNSVLPGFIATP-MTQ----------KMPEKVKDKVTAMIPLGHMGDPEG 230
Query: 231 EIGYLVAFLASDLGSYINGAMIPVDGG 257
++ +VAFLAS+ YI GA + V GG
Sbjct: 231 DVADVVAFLASEDSGYITGASVEVSGG 257
>gb|AAK42451.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-6) [Sulfolobus
solfataricus]
Length = 259
Score = 85.0 bits (207), Expect = 8e-16
Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 24/261 (9%)
Query: 9 KLAFTTASSKGIGFGVARV-LAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
K+ T ++GIG + L + G +++ + E+ K+ REK V I D+
Sbjct: 12 KVILITGGTRGIGRAITEAFLREGGLPIVLYNSAEDEAKKLREK-------GVFTIKCDV 64
Query: 68 TKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEA-----VKLLLYPAIY 122
+D VK+ K I E + + G + M E+++E +++ L IY
Sbjct: 65 GNRED----VKKSKEIVEKEFRRVNVVVNNAGIMLTMPFEEFDEEKYNKMIRINLNGTIY 120
Query: 123 LTKALVPAMERKGFGRII-YSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
T +P ++ G I+ +++ I + + ++ L + LA ELG GI
Sbjct: 121 TTYEFLPLLKASENGAIVNIASNAGIGTAAEGTTFYAITKASIIILTKRLAFELGKYGIR 180
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
VN + PG + TD + ++K E VE + L G+PE+I +V FLAS
Sbjct: 181 VNAVAPGWVETDMTLS---GKSKEE---VERLRDLFRNKTVLKTTGKPEDIANIVLFLAS 234
Query: 242 DLGSYINGAMIPVDGGRLNSV 262
+ YI G +I DGGR++++
Sbjct: 235 NEARYITGQVIVADGGRIDNL 255
>pir||A64590 probable 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)
- Helicobacter pylori (strain 26695)
>gi|2313678|gb|AAD07627.1| (AE000570) 3-ketoacyl-acyl
carrier protein reductase (fabG) [Helicobacter pylori
26695]
Length = 247
Score = 85.0 bits (207), Expect = 8e-16
Identities = 66/255 (25%), Positives = 106/255 (40%), Gaps = 12/255 (4%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ +GK T +SKGIG +A+ LA G V I R+ + A + EE + I
Sbjct: 1 MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI 60
Query: 64 VADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D D ++ + ++ G + G + ++M ED+ + L A
Sbjct: 61 KFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI 120
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+ + M + FG ++ S+ + + + M + ++ A E + I
Sbjct: 121 GCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF 180
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG I TD L +E +Y K IPL RLG +E+ VAFL SD
Sbjct: 181 NSVTPGFIETDMNANLK-----------DELKADYVKNIPLNRLGSAKEVAEAVAFLLSD 229
Query: 243 LGSYINGAMIPVDGG 257
SYI G + V+GG
Sbjct: 230 HSSYITGETLKVNGG 244
>gb|AAF64503.1|AF247810_1 (AF247810) cholesterol oxidase [Nocardioides simplex]
Length = 270
Score = 85.0 bits (207), Expect = 8e-16
Identities = 77/272 (28%), Positives = 119/272 (43%), Gaps = 31/272 (11%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV------- 60
GK+AF T +++G G A LA GAD+I + + A + E E
Sbjct: 8 GKVAFITGAARGQGRAEAVRLASEGADIIAIDACADFDSTAYDGATEADLAETVAQVEAQ 67
Query: 61 -HYIVADLTKMDDLERTVKELKN----IGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKL 115
IVA T + D + L +G D+ + G E++ E W+E + +
Sbjct: 68 GRKIVATKTDVRDFAAVSEALATGIAALGRLDVVVANAGICSGAMSWEITPEQWQETLDV 127
Query: 116 LLYPAIYLTKALVPAMERKGFG-RIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKE 174
L + KA +P + +G G I+ ++SVA +P + + + GL +TLA E
Sbjct: 128 NLTGVFHTCKAAIPHLIEQGEGGSIVIASSVAGLRGLPFLGHYVASKHGVTGLAKTLAVE 187
Query: 175 LGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAK---PIPLGRLGE--- 228
LG I VN + P + T + + +QEYA PI +G L +
Sbjct: 188 LGAHNIRVNTVHPNGVDTGMQVN-----------DMHALVQEYATTLAPIFMGSLPDQIS 236
Query: 229 -PEEIGYLVAFLASDLGSYINGAMIPVDGGRL 259
PE+I VA+LASD ++ G +PVD G L
Sbjct: 237 RPEDIANAVAWLASDEARHVTGIQLPVDLGTL 268
>gb|AAC79985.1| (AF053764) NADP-dependent mannitol dehydrogenase [Agaricus
bisporus]
Length = 262
Score = 84.7 bits (206), Expect = 1e-15
Identities = 66/265 (24%), Positives = 125/265 (46%), Gaps = 20/265 (7%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
I K T ++GIG R +A AGA+V ++ R+ ++ EK+ +E V+
Sbjct: 7 ISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAKDAVEVTEKVGKEFGVKTKAY 66
Query: 64 VADLTKMDDLERTVKEL-KNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D++ D + +T++++ ++G + G E++ ED++ + ++
Sbjct: 67 QCDVSNTDIVTKTIQQIDADLGAISGLIANAGVSVVKPATELTHEDFKFVYDVNVFGVFN 126
Query: 123 LTKALVPA-MERKGFGRIIYSTSVA---IKEPIPNIALSNVV----RIAMAGLVRTLAKE 174
+A+ ++++ G I+ ++S++ I + N +L+ V + A + LV+ LA E
Sbjct: 127 TCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAE 186
Query: 175 LGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGY 234
GI VN + PG + TD+ + D+ R+ A IPL R +PEE+
Sbjct: 187 WASAGIRVNALSPGYVNTDQTAHM--DKKIRD---------HQASNIPLNRFAQPEEMTG 235
Query: 235 LVAFLASDLGSYINGAMIPVDGGRL 259
L SD +Y+ G +DGG+L
Sbjct: 236 QAILLLSDHATYMTGGEYFIDGGQL 260
>gb|AAF63451.1|AF218267_8 (AF218267) cis-diol dehydrogenase [Pseudomonas putida]
Length = 253
Score = 84.7 bits (206), Expect = 1e-15
Identities = 72/258 (27%), Positives = 119/258 (45%), Gaps = 18/258 (6%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GK+A T +++GIG GV L GA V+ + R+E + E + + + ADL
Sbjct: 7 GKVALVTGAAQGIGRGVCWRLKAEGAQVVAVDRSE--------LVHELAGEGMLTLTADL 58
Query: 68 TKMDDLERTVKE-LKNIGEPDIFFFSTGGP---KPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ D R + ++ G DI + GG KP F +E E V+ L+P ++
Sbjct: 59 EQHTDCARVMASAVETFGRLDILVNNVGGTIWAKP--FEHYEVEQIEAEVRRSLFPTLWC 116
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
A +P M +G G I+ +S+A + N + + L LA E +GI VN
Sbjct: 117 CHAALPYMLERGSGAIVNVSSIATRGV--NRVPYGAAKGGVNALTACLAFETAGRGIRVN 174
Query: 184 GIMPGIIRTD--RMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
PG R+ + + +++++E + ++ + + + R G +E + FLAS
Sbjct: 175 ATAPGGTEAPPRRVPRNSAEQSEQEKRWYQQIVDQTLDSSLMHRYGSIDEQVGAILFLAS 234
Query: 242 DLGSYINGAMIPVDGGRL 259
D SYI G +PV GG L
Sbjct: 235 DEASYITGVTLPVGGGDL 252
>gb|AAF45573.1| (AE003419) EG:BACR7A4.14 gene product [Drosophila melanogaster]
Length = 270
Score = 84.3 bits (205), Expect = 1e-15
Identities = 54/186 (29%), Positives = 97/186 (52%), Gaps = 7/186 (3%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ LS K+ T +S GIG +A+VLA+ GA + ++ RN NL+ ++ +K + +
Sbjct: 1 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLK---GTQAEIV 57
Query: 64 VADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
VAD+TK D + V++ L G D+ + G G +++ +E+++ + L I
Sbjct: 58 VADVTK--DADAIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVIL 115
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
LTKA++P + K G ++ +S A P V + A+ + +A E+ P+G+ V
Sbjct: 116 LTKAVLPHL-LKTKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRV 174
Query: 183 NGIMPG 188
N + PG
Sbjct: 175 NSVNPG 180
>gi|7305125 H2-K region expressed gene 6 [Mus musculus]
>gi|1103845|gb|AAC53574.1| (U34072) steroid
dehydrogenase [Mus musculus]
Length = 275
Score = 83.9 bits (204), Expect = 2e-15
Identities = 75/268 (27%), Positives = 123/268 (44%), Gaps = 25/268 (9%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRN----EENLKRAREKIKEESNV 58
++ L LA T + GIG ++ LA GA V + ++ ++ E+
Sbjct: 4 QLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAP 63
Query: 59 EVHYIV--ADLTKMDDLERTVKELKNIGE--PDIFFFSTGGPKPGYFMEMSMEDWEEAVK 114
+ AD+++ R ++E++ P + G + + + MS EDW+ +
Sbjct: 64 RGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIA 123
Query: 115 LLLYPAIYLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVV--RIAMAGLVRTL 171
+ L +T+A A+ G G II +S+ K + NI +N + + GL +T
Sbjct: 124 VNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGK--VGNIGQTNYASSKAGVIGLTQTA 181
Query: 172 AKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPE- 230
A+ELG GI N ++PG I T M Q K E+ + IPLG +G+PE
Sbjct: 182 ARELGRHGIRCNSVLPGFIATP-MTQ----------KMPEKVKDKVTAMIPLGHMGDPEG 230
Query: 231 EIGYLVAFLASDLGSYINGAMIPVDGGR 258
++ +VAFLAS+ YI GA + V G R
Sbjct: 231 DVADVVAFLASEDSGYITGASVEVSGMR 258
>pir||T07698 short-chain alcohol dehydrogenase homolog F17N18.70 - Arabidopsis
thaliana >gi|4753652|emb|CAB41928.1| (AL049751)
short-chain alcohol dehydrogenase like protein
[Arabidopsis thaliana] >gi|7268020|emb|CAB78360.1|
(AL161535) short-chain alcohol dehydrogenase like
protein [Arabidopsis thaliana]
Length = 263
Score = 83.9 bits (204), Expect = 2e-15
Identities = 69/260 (26%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVII-----LSRNEENLKRAREKIKEESNV 58
+ L+G++A T +++G+G +A L GA V I S+ E + + + +S +
Sbjct: 11 LPLAGRVAIVTGATRGMGREIAIHLHSLGARVTINYVSSSSKAELLVSELNDSSQLKSAI 70
Query: 59 EVHYIVADLTKMDDL-ERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLL 117
V V+D ++++L ++T +E + + PK E ++ED++ +
Sbjct: 71 AVKADVSDPDQINNLFDQTEQEFGSKVHIVVNCAGVLDPKYPSLSETTLEDFDNTFTINT 130
Query: 118 YPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGP 177
+ K + R G GRII ++ + P + + A+ +V+ LAKEL
Sbjct: 131 RGSFLCCKEAAKRVMRGGGGRIIMMSTSMVGGLAPGYGVYAASKAAVETMVKVLAKELKG 190
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVA 237
IT N + PG + T+ GK+ +E ++ A P+GR+GE ++I +V
Sbjct: 191 SRITANCVAPGPVATEMFYA---------GKS-DETVKMLAGACPMGRIGESKDITEIVG 240
Query: 238 FLASDLGSYINGAMIPVDGG 257
FLA D G +ING +I +GG
Sbjct: 241 FLAGDGGEWINGQVIRANGG 260
>gb|AAF05859.1|AC011698_10 (AC011698) putative short-chain type dehydrogenase/reductase
[Arabidopsis thaliana]
Length = 272
Score = 83.9 bits (204), Expect = 2e-15
Identities = 67/268 (25%), Positives = 121/268 (45%), Gaps = 24/268 (8%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVII-LSRNEENLKRAREKIKEESNVE----- 59
L+G++A T SS+GIG +A LA+ GA V++ S + ++ I + +
Sbjct: 14 LAGRVAIVTGSSRGIGRAIAIHLAELGARVVVNYSTSPVEAEKVATAITTNCSKDAEVAG 73
Query: 60 ----VHYIVADLTKMDDLERTVKELKNIGEPDIFFF----STGGPKPGYFMEMSMEDWEE 111
V + AD+++ ++ E + + E + + P +MS+E ++
Sbjct: 74 KSPRVIVVKADISEPSQVKSLFDEAERVFESPVHILVNSAAIADPNHSTISDMSVELFDR 133
Query: 112 AVKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTL 171
+ + A + ++R G GRII ++ ++ N + A+ + + L
Sbjct: 134 IISVNTRGAFICAREAANRLKRGGGGRIILLSTSLVQTLNTNYGSYTASKAAVEAMAKIL 193
Query: 172 AKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEE 231
AKEL ITVN + PG + T+ + E +++ GR+GE ++
Sbjct: 194 AKELKGTEITVNCVSPGPVATEMFYTGLSN----------EIVEKVKSQNLFGRIGETKD 243
Query: 232 IGYLVAFLASDLGSYINGAMIPVDGGRL 259
I +V FLASD G +ING +I +GG L
Sbjct: 244 IAPVVGFLASDAGEWINGQVIMANGGCL 271
>sp|P15047|ENTA_ECOLI 2,3-DIHYDRO-2,3-DIHYDROXYBENZOATE DEHYDROGENASE
>gi|65912|pir||DEECDB 2,3-dihydro-2,3-dihydroxybenzoate
dehydrogenase (EC 1.3.1.28) - Escherichia coli
>gi|450382|gb|AAA16103.1| (M24148)
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
[Escherichia coli] >gi|522183|gb|AAA76836.1| (M24143)
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
[Escherichia coli] >gi|1786812|gb|AAC73697.1| (AE000165)
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase,
enterochelin biosynthesis [Escherichia coli K12]
Length = 248
Score = 83.1 bits (202), Expect = 3e-15
Identities = 70/259 (27%), Positives = 118/259 (45%), Gaps = 21/259 (8%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSR--NEENLKRAREKIKEESNVEVH 61
+D SGK + T + KGIG+ A +AGA V + +E A E +
Sbjct: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMD-------- 52
Query: 62 YIVADLTKMDDL-ERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
VAD ++ + +R + E + + D + G + G ++S EDW++ + + A
Sbjct: 53 --VADAAQVAQVCQRLLAETERL---DALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 107
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
L + + R+ G I+ S A P ++ + A+ L ++ EL G+
Sbjct: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167
Query: 181 TVNGIMPGIIRTD--RMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
N + PG TD R + ++ D E + + +++ IPLG++ P+EI + F
Sbjct: 168 RCNVVSPGSTDTDMQRTLWVSDDA---EEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224
Query: 239 LASDLGSYINGAMIPVDGG 257
LASDL S+I I VDGG
Sbjct: 225 LASDLASHITLQDIVVDGG 243
>gb|AAB40796.1| (U82598) 2,3-dihydro-2,3-dihydroxybenzoate [Escherichia coli]
Length = 258
Score = 83.1 bits (202), Expect = 3e-15
Identities = 70/259 (27%), Positives = 118/259 (45%), Gaps = 21/259 (8%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSR--NEENLKRAREKIKEESNVEVH 61
+D SGK + T + KGIG+ A +AGA V + +E A E +
Sbjct: 11 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMD-------- 62
Query: 62 YIVADLTKMDDL-ERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
VAD ++ + +R + E + + D + G + G ++S EDW++ + + A
Sbjct: 63 --VADAAQVAQVCQRLLAETERL---DALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 117
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
L + + R+ G I+ S A P ++ + A+ L ++ EL G+
Sbjct: 118 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 177
Query: 181 TVNGIMPGIIRTD--RMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAF 238
N + PG TD R + ++ D E + + +++ IPLG++ P+EI + F
Sbjct: 178 RCNVVSPGSTDTDMQRTLWVSDDA---EEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 234
Query: 239 LASDLGSYINGAMIPVDGG 257
LASDL S+I I VDGG
Sbjct: 235 LASDLASHITLQDIVVDGG 253
>emb|CAA07756.1| (AJ007932) ketoreductase [Streptomyces argillaceus]
Length = 253
Score = 83.1 bits (202), Expect = 3e-15
Identities = 74/268 (27%), Positives = 116/268 (42%), Gaps = 26/268 (9%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ + L+G+ T S GIG VAR A GA V + R + A E++ E H
Sbjct: 1 MDMGLTGRRVLVTGGSSGIGAAVARAYADEGARVALTYRGGDE---AAERLARELGAGRH 57
Query: 62 YIVA---DLTKMDDLERTVKEL-KNIGEPDIFFFST--GGPK--PGY-FMEMSMEDWEEA 112
+A L + D +E V + + G D+ + P+ PG F E++ DW
Sbjct: 58 AAMAVRYSLGEPDTVESAVATVTERWGGVDVLVANAVRWAPRRAPGTRFEEVASGDWRGF 117
Query: 113 VKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLA 172
+ L P + + +V M + +GRI+ +S + + A+ G R+LA
Sbjct: 118 LDDNLAPTLRTVQLVVAGMRARSWGRIVLISSHVALDGHRGQEFYGAAKSALHGFARSLA 177
Query: 173 KELGPKGITVNGIMPGIIRTDRMIQLAQD--RAKREGKTVEEALQEYAKPIPLGRLGEPE 230
++G G+ VN + PG+ T+R++ D R + G T P GRL PE
Sbjct: 178 WDVGRDGVLVNVVCPGLTTTERVLTGLPDEIRERELGST------------PTGRLSSPE 225
Query: 231 EIGYLVAFLASDLGSYINGAMIPVDGGR 258
+I V FL S + G + V GGR
Sbjct: 226 DIAGAVLFLGSAANANTTGQTLTVSGGR 253
>gb|AAF60668.1| (AC024791) Hypothetical protein Y47G6A.22 [Caenorhabditis elegans]
Length = 254
Score = 83.1 bits (202), Expect = 3e-15
Identities = 66/253 (26%), Positives = 118/253 (46%), Gaps = 11/253 (4%)
Query: 10 LAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKR-AREKIKEESNVEVHYIVADLT 68
+A T +S GIG A +LA+ + + RN L A + + S+ + A
Sbjct: 3 VAIVTGASSGIGRAAALLLARNNYKLSLTGRNVAALNELAGQIVSAGSDKNDVLVTAVEL 62
Query: 69 KMDDLERTVKE--LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKA 126
++ +T+ + ++ G D S G + G ++ +E ++E + + + I LT+A
Sbjct: 63 ASEEAPKTIVDATVQKFGRIDTLINSAGILRAGPVLDSGIEVYDELMNVNVRSLIRLTRA 122
Query: 127 LVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
+P + G ++ +S+ P PN+ + + A+ + LA E+ P G+ VN +
Sbjct: 123 ALPHIITTK-GTVVNVSSINGPCPFPNVTYYCMSKSAVDQFTKCLALEMAPNGVRVNAVC 181
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPI-PLGRLGEPEEIGYLVAFLASDLGS 245
PG+ T+ QD +T A E +K LGR G+ E+ + FLAS+ S
Sbjct: 182 PGVTVTNLHRTSGQD------ETTYSAFLERSKTTHALGRPGDANEVAEAIYFLASEKSS 235
Query: 246 YINGAMIPVDGGR 258
+ G ++ VDGGR
Sbjct: 236 FTTGELLRVDGGR 248
>emb|CAB61164.1| (AL132973) short chain oxidoreductase [Streptomyces coelicolor
A3(2)]
Length = 265
Score = 82.3 bits (200), Expect = 5e-15
Identities = 52/190 (27%), Positives = 98/190 (51%), Gaps = 3/190 (1%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+D S LA T +S GIG+ +A + A+ G D+++ + +E L+ A +++E + V V +
Sbjct: 1 MDGSRPLALVTGASSGIGYELAALFAEHGYDLVV-NAEDERLEHAARRLRE-TGVRVRAV 58
Query: 64 VADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
ADL D ++ + L + D+ + G + G F++ + D + + L + + L
Sbjct: 59 RADLRHPDGVDHLIAALTGLAV-DVAALNAGVGQGGAFVDTDLADDQSVIDLDVTATVRL 117
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
K L+ M +G GR+++++SVA P ++ N + + + L +E+ G+TV
Sbjct: 118 AKPLLRDMVARGVGRLMFTSSVAATMPGSFQSVYNASKSFVQSFAQALQEEVAGTGVTVT 177
Query: 184 GIMPGIIRTD 193
MPG TD
Sbjct: 178 SFMPGPTETD 187
>gi|6671688 carbonyl reductase 2 [Mus musculus] >gi|113986|sp|P08074|CBR2_MOUSE
LUNG CARBONYL REDUCTASE [NADPH] (NADPH-DEPENDENT
CARBONYL REDUCTASE) (LCR) (ADIPOCYTE P27 PROTEIN) (AP27)
>gi|90271|pir||A28053 carbonyl reductase (NADPH) (EC
1.1.1.184) - mouse >gi|1827689|pdb|1CYD|A Chain A,
Carbonyl Reductase Complexed With Nadph And 2-Propanol
>gi|1827690|pdb|1CYD|B Chain B, Carbonyl Reductase
Complexed With Nadph And 2-Propanol
>gi|1827691|pdb|1CYD|C Chain C, Carbonyl Reductase
Complexed With Nadph And 2-Propanol
>gi|1827692|pdb|1CYD|D Chain D, Carbonyl Reductase
Complexed With Nadph And 2-Propanol
>gi|50004|emb|CAA30309.1| (X07411) Ap27 protein (AA 1 -
244) [Mus musculus] >gi|699608|dbj|BAA05120.1| (D26123)
carbonyl reductase [Mus musculus]
Length = 244
Score = 81.5 bits (198), Expect = 9e-15
Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 18/261 (6%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+K++ SG A T + KGIG + L +GA V+ ++R +L KE +E
Sbjct: 1 MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLA---KECPGIEP- 56
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ DL D + T K L IG D+ + F+E++ E ++ + + L
Sbjct: 57 -VCVDL---GDWDATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVF 112
Query: 122 YLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+++ + M +G G I+ +S+ PN+ + + AM L + +A ELGP I
Sbjct: 113 QVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKI 172
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN + P ++ TD +++ D E ++ + PL + E E++ + FL
Sbjct: 173 RVNSVNPTVVLTDMGKKVSAD---------PEFARKLKERHPLRKFAEVEDVVNSILFLL 223
Query: 241 SDLGSYINGAMIPVDGGRLNS 261
SD + +G I VD G L S
Sbjct: 224 SDRSASTSGGGILVDAGYLAS 244
>gb|AAD03695.1| (AF090422) surface sperm protein P26h [Mesocricetus auratus]
Length = 244
Score = 81.5 bits (198), Expect = 9e-15
Identities = 73/265 (27%), Positives = 123/265 (45%), Gaps = 26/265 (9%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+K++ +G A T + +GIG G A+ L +GA V+ +S E+L KE +E
Sbjct: 1 MKLNFTGLRALVTGAGRGIGRGTAKALHASGAKVVAVSLINEDLV---SLAKECPGIEP- 56
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ DL D E T K L IG D+ + F++ + E ++ + + + +
Sbjct: 57 -VCVDL---GDWEATEKALGRIGPVDLLVNNAAVALVQPFIQSTKEVFDRSFNVNVRSVL 112
Query: 122 YLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+++ + M +G G I+ +S+ P +A + + A+ L + +A ELGP I
Sbjct: 113 QVSQMVAKGMINRGVAGSIVNISSMVAYVTFPGLATYSSTKGAITMLTKAMAMELGPYKI 172
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPI----PLGRLGEPEEIGYLV 236
VN + P ++ TD GK V A E+AK + PL + E E++ +
Sbjct: 173 RVNSVNPTVVLTDM------------GKKV-SADPEFAKKLKERHPLRKFAEVEDVVNSI 219
Query: 237 AFLASDLGSYINGAMIPVDGGRLNS 261
FL SD + +G+ I VD G L S
Sbjct: 220 LFLLSDSSASTSGSGILVDAGYLAS 244
>gi|7705925 carbonyl reductase [Homo sapiens]
>gi|6523809|gb|AAF14864.1|AF113123_1 (AF113123) carbonyl
reductase [Homo sapiens]
Length = 244
Score = 81.5 bits (198), Expect = 9e-15
Identities = 66/257 (25%), Positives = 120/257 (46%), Gaps = 18/257 (7%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+++ L+G+ T + KGIG G + L GA V+ +SR + +L ++E +E
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSL---VRECPGIEP- 56
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ DL D E T + L ++G D+ + F+E++ E ++ + ++ L I
Sbjct: 57 -VCVDL---GDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI 112
Query: 122 YLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+++ + + +G G I+ +S + + N ++ + A+ L + +A ELGP I
Sbjct: 113 QVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKI 172
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN + P ++ T D K KT+ IPLG+ E E + + FL
Sbjct: 173 RVNAVNPTVVMTSMGQATWSDPHK--AKTM-------LNRIPLGKFAEVEHVVNAILFLL 223
Query: 241 SDLGSYINGAMIPVDGG 257
SD G+ +PV+GG
Sbjct: 224 SDRSGMTTGSTLPVEGG 240
>pir||T02176 hypothetical protein F14M4.5 - Arabidopsis thaliana
>gi|3522936|gb|AAC34218.1| (AC004411) putative alcohol
dehydrogenase [Arabidopsis thaliana]
Length = 258
Score = 80.8 bits (196), Expect = 2e-14
Identities = 72/260 (27%), Positives = 123/260 (46%), Gaps = 14/260 (5%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
M + L GK+ T + GIG AR+ GA V+I+ EE + I ++ +
Sbjct: 1 MSGLRLEGKIVIITGGASGIGADAARLFTDHGAKVVIVDVQEELGQNVAVLIGKD---KA 57
Query: 61 HYIVADLTKMDDLERTVK-ELKNIGEPDIFFFSTGGPKP-GYFMEMSMEDWEEAVKLLLY 118
+ D+T ++E VK ++ G+ D+ F + G +P F++ +E ++ + + +
Sbjct: 58 SFYRCDVTNETEVEDAVKFTVEKHGKLDVLFSNAGVLEPLESFLDFDLERFDRIMAVNVR 117
Query: 119 PAIYLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGP 177
A K AM KG G I+ +TSV+ + + + + + GL+R+ +LG
Sbjct: 118 GAAAFIKHAARAMVEKGTRGSIVCTTSVSAEIGGGHHGYT-ASKHGLVGLIRSACGDLGK 176
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVA 237
GI VNG+ P + T + D GK +E+ AK I G + + + +
Sbjct: 177 YGIRVNGVAPYAVATP---MTSHDEV--TGKQLEDYFD--AKGILKGMVLKASHVAQVAL 229
Query: 238 FLASDLGSYINGAMIPVDGG 257
FLASD +YI+G + VDGG
Sbjct: 230 FLASDDSAYISGQNLAVDGG 249
>pir||T50271 probable oxidoreductase, short chain dehydrogenase/reductase family
[imported] - fission yeast (Schizosaccharomyces pombe)
>gi|6594240|emb|CAB63553.1| (AL133522) probable
oxidoreductase, short chain dehydrogenase/reductase
family [Schizosaccharomyces pombe]
Length = 258
Score = 80.4 bits (195), Expect = 2e-14
Identities = 66/257 (25%), Positives = 113/257 (43%), Gaps = 23/257 (8%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIV- 64
+ G++ T ++ GIG + ++ + G V A I + S V+ +
Sbjct: 3 VEGRVVLITGAAGGIGKVLCKMFTELGDRV------------AGIDIVDPSKVQDAALAL 50
Query: 65 -ADLTKMDDLERTV-KELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
AD++K D +E + K ++ +G D+ + G F ++S E W+ V L+L
Sbjct: 51 QADVSKADQIETAIEKVIQTLGPIDVLINNAGLADDTPFEQLSHESWDHDVSLVLRGNYL 110
Query: 123 LTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+ ++P M ++G G I + + + + L + LA GP GI V
Sbjct: 111 TQRYVIPHMAKQGKGGSIVNIGSVNGHIYLGSPAYSAAKAGLENLTKALAVRYGPLGIRV 170
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N PG I + A D ++ V + ++ + P+GRLG PE++ V FLA
Sbjct: 171 NVCAPGTIWSP-----AWDERFKKHPDVGDRMKRW---YPVGRLGTPEDVARAVIFLADS 222
Query: 243 LGSYINGAMIPVDGGRL 259
S+I G + VDGG L
Sbjct: 223 KNSFITGTTLYVDGGLL 239
>emb|CAA07629.1| (AJ007731) 3-ketoacyl-ACP/CoA redutase [Streptomyces coelicolor
A3(2)]
Length = 244
Score = 79.6 bits (193), Expect = 4e-14
Identities = 73/253 (28%), Positives = 114/253 (44%), Gaps = 18/253 (7%)
Query: 14 TASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTKMDD- 72
T S+GIG G+A LA GA V + + E R + S + I A+L + D
Sbjct: 2 TGGSRGIGRGIALRLAADGALVAVHYGSSEAAARETVETIRSSGGQALAIRAELGVVGDA 61
Query: 73 ------LERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKA 126
+ + E E DI + G G E++ E ++ V + + ++L +
Sbjct: 62 AALYAAFDAGMGEFGVPPEFDILVNNAGVSGSGRITEVTEEVFDRLVAVNVRAPLFLVQH 121
Query: 127 LVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIM 186
+ + R G GRII +S A + P + + A+ L LA++LG +GITVN +
Sbjct: 122 GLKRL-RDG-GRIINISSAATRRAFPESIGYAMTKGAVDTLTLALARQLGERGITVNAVA 179
Query: 187 PGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSY 246
PG + TD A+R + EA A R+G P++I +VAFLASD +
Sbjct: 180 PGFVETDM-------NARR--RQTPEAAAALAANSVFNRIGRPDDIADVVAFLASDDSRW 230
Query: 247 INGAMIPVDGGRL 259
I G + GG +
Sbjct: 231 ITGQYVDATGGTI 243
>dbj|BAB04426.1| (AP001509) D-mannonate oxidoreductase [Bacillus halodurans]
Length = 284
Score = 79.6 bits (193), Expect = 4e-14
Identities = 70/277 (25%), Positives = 116/277 (41%), Gaps = 27/277 (9%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHY 62
++DL+ K+A T S +G LAK GA V ++ R ++ LK +I E
Sbjct: 6 QVDLTNKVAVVTGGSGVLGREFCLALAKCGAKVAVIGRTDDKLKAIVNEIIVNGG-EAIA 64
Query: 63 IVADLTKMDDLERTVKELK-NIGEPDIFFFSTGGPKP------GYFMEMSMEDWEEAVKL 115
I AD+ D+ER ++++ +G D+ GG P Y E + ++ V+
Sbjct: 65 ISADVLAKTDMERAREQVRTELGTCDLLINGAGGNHPKGTTQLDYLREADLHGIDQDVRT 124
Query: 116 LL---------YPAIYLTKALVPA------MERKGFGRIIYSTSVAIKEPIPNIALSNVV 160
+ L+P M K I+ +S+ P+ I +
Sbjct: 125 FFDLDADGIRHVFELNFLGTLIPCQVFSQDMLGKEGASIVNISSMNAFTPLTRIPAYSGA 184
Query: 161 RIAMAGLVRTLAKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKP 220
+ A++ + LA GI VN I PG T++ L K +G T + +
Sbjct: 185 KAAVSNFTQWLAVHFSKVGIRVNAIAPGFFLTEQNYSLL---VKDDG-TYTDRANKILSQ 240
Query: 221 IPLGRLGEPEEIGYLVAFLASDLGSYINGAMIPVDGG 257
P R G+PEE+ + +L S++NG ++PVDGG
Sbjct: 241 TPAERFGKPEELISTLLWLVDSSTSFVNGVIVPVDGG 277
>emb|CAC01650.1| (AL391072) putative oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 260
Score = 79.2 bits (192), Expect = 5e-14
Identities = 62/254 (24%), Positives = 107/254 (41%), Gaps = 15/254 (5%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+ +G A T + GIG AR+L GA V +L +E ++ + + +
Sbjct: 12 LPFAGLTALVTGGASGIGLATARLLTAQGARVAVLDLSEPQPAGFAAALRADIRDDASVV 71
Query: 64 VADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
A ++ V L G DI + G G + S E+W + + + +
Sbjct: 72 AA-------VDAAVSRL---GGLDIVVNNAGIGAQGGVEDNSDEEWHRVLDTNVVGMVRV 121
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
T+A +PA+ ++ S+A +P L + + A+ + R +A +L P+GI VN
Sbjct: 122 TRAALPALRASRHAAVVNVGSIAATAGLPQRVLYSAGKGAVVAMTRAMAADLLPEGIRVN 181
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDL 243
+ PG T + +L A + A ++ P GRL +E+ +A+LAS
Sbjct: 182 AVNPGTADTPWIGRLLDRAADPAAEYTALAARQ-----PHGRLVAADEVAAAIAYLASPA 236
Query: 244 GSYINGAMIPVDGG 257
G + VDGG
Sbjct: 237 AGSTTGTCLAVDGG 250
>dbj|BAB04225.1| (AP001508) dehydrogenase/reductase [Bacillus halodurans]
Length = 260
Score = 79.2 bits (192), Expect = 5e-14
Identities = 74/278 (26%), Positives = 116/278 (41%), Gaps = 40/278 (14%)
Query: 5 DLSGKLAFTTASSK--GIGFGVARVLAKAGADVI------------ILSRNEENLKRARE 50
+L GK A T S+ GIG + R AK GADV + N+E ++ A+E
Sbjct: 3 NLHGKRAIVTGVSRLSGIGAAICREFAKRGADVFFTYYFHYDQTLGVKGENDEPMRLAKE 62
Query: 51 KIKEESNVEVHYIVADLTKMDDLERTVKELKNIGEP------DIFFFSTGGPKPGYFMEM 104
E V V ++ DL++ + ++ N E DI + + +
Sbjct: 63 L--ESHGVAVAHLELDLSE----DNAYVQIFNAFEQRFGTTADILVNNACVSVNDSYETI 116
Query: 105 SMEDWEEAVKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAM 164
+ E+ + + + LT + GRII T+ + P+ N + + +
Sbjct: 117 TSENLDAHYVINVRATTLLTSEFAKRFSKGHGGRIIQLTTGWSQGPMANELSYAITKSTV 176
Query: 165 AGLVRTLAKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLG 224
L TL EL KGIT+N + PG G ++ QE P G
Sbjct: 177 EALTYTLKTELAKKGITINAVNPG--------------PTNSGWMSDQLKQELLPRFPFG 222
Query: 225 RLGEPEEIGYLVAFLASDLGSYINGAMIPVDGGRLNSV 262
RLGEP++ L+AFLASD +I G +I +GG N++
Sbjct: 223 RLGEPKDAANLIAFLASDDAEWITGQVIHSEGGFQNTL 260
>emb|CAB77292.1| (AL160312) putative 3-oxoacyl-[acyl-carrier protein] reductase
[Streptomyces coelicolor A3(2)]
Length = 430
Score = 78.8 bits (191), Expect = 6e-14
Identities = 70/259 (27%), Positives = 113/259 (43%), Gaps = 22/259 (8%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILS--RNEENLKRAREKIKEESNVEVH 61
+ L+G+ A T +++GIG VA LA GA V++L + EE +RA E++ +
Sbjct: 188 LPLAGRTALVTGAARGIGAAVAETLAGQGAQVVVLDVPQAEEAARRAAERLGGTA----- 242
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ D+T D ER L G D+ + G + + M + W + + L +
Sbjct: 243 -LALDITAADAGERIAAALP--GGLDVLVHNAGITRDRRLVNMPADRWSSVLDVNLASVL 299
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLA-KELGPKGI 180
T AL+ A GRI+ + S+A + + GLVR+LA + L G+
Sbjct: 300 RTTDALLAAGAVNRGGRIVATASIAGLAGNAGQTNYGASKAGIVGLVRSLAPRALAGHGV 359
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
TVN + PG I T RM + G+ + L + G P ++ A+LA
Sbjct: 360 TVNAVAPGFIET-RMTAAVPLFIREAGRRMNS----------LAQGGLPVDVAETTAWLA 408
Query: 241 SDLGSYINGAMIPVDGGRL 259
+NG ++ V G L
Sbjct: 409 HPASGAVNGQVVRVCGQSL 427
>emb|CAC14380.1| (AL445963) putative oxidoreductase [Streptomyces coelicolor]
Length = 266
Score = 78.4 bits (190), Expect = 8e-14
Identities = 68/255 (26%), Positives = 111/255 (42%), Gaps = 8/255 (3%)
Query: 4 IDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYI 63
+DL G+ A T ++ GIG A LA AGA+V + R+ L+ + + V
Sbjct: 15 LDLHGRTALVTGAAGGIGRACALRLAAAGAEVRAVDRDAAGLEALAGSCGDLAG-SVEPQ 73
Query: 64 VADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
V DLT +D ER D+ + G E + + + ++L L
Sbjct: 74 VLDLTDLDAAERAA------AGTDVLVNNAGLQLVRPLEEFPPDVFHTVLTVMLEAPFRL 127
Query: 124 TKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+ +P M +G+GRI+ +SV A + + GL +T A E G+T N
Sbjct: 128 IRGALPHMYGQGWGRIVNISSVHGLRASAYKAAYVSAKHGLEGLSKTAALEGAAHGVTSN 187
Query: 184 GIMPGIIRTDRMIQLAQDRAKREGKTVEEALQE-YAKPIPLGRLGEPEEIGYLVAFLASD 242
+ P +RT + + D+A+ G E+ L + + L RL EP+E+ VA+L
Sbjct: 188 CVNPAYVRTPLVERQIADQARAHGLPEEQVLSDVLLRDSALRRLIEPDEVAEAVAYLCGP 247
Query: 243 LGSYINGAMIPVDGG 257
+ G + +DGG
Sbjct: 248 YTVGLTGTSLVLDGG 262
>emb|CAB69778.1| (AL137187) putative dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 255
Score = 77.6 bits (188), Expect = 1e-13
Identities = 64/256 (25%), Positives = 115/256 (44%), Gaps = 13/256 (5%)
Query: 7 SGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVAD 66
+GK A T + GIG VA LA GA V++ R L + E++ + + AD
Sbjct: 7 TGKTALVTGAGSGIGRAVALALAAEGAHVVVAGRARGPLDETAALV-EQAGGKALAVTAD 65
Query: 67 LTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGY-FMEMSMEDWEEAVKLLLYPAIYLT 124
+T+ +D++ V +++ G D+ + G + G ++S EDW + + +
Sbjct: 66 VTRREDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVFLAL 125
Query: 125 KALVPAMERK-GFGRII-YSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
+A V M + G G I+ +++ + P + A++ L R A + G+ +
Sbjct: 126 RAEVRHMRAQPGGGTIVNIASTFGAHKRSPGATAYAATKAAVSALTRGAALDHIGDGVRI 185
Query: 183 NGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
N + PG T ++ + A R + +E PLGR+ E+ V +LASD
Sbjct: 186 NAVSPGATATSMSLRPGETEAGRAERMRQET--------PLGRVSAVAEVAAAVLYLASD 237
Query: 243 LGSYINGAMIPVDGGR 258
+ + G + VDGG+
Sbjct: 238 DAASVVGTDLVVDGGQ 253
>sp|P23102|XYLL_PSEPU CIS-1,2-DIHYDROXYCYCLOHEXA-3,5-DIENE-1-CARBOXYLATE DEHYDROGENASE
(CIS-1,2-DIHYDROXY-3,4-CYCLOHEXADIENE-1-CARBOXYLATE
DEHYDROGENASE) (2-HYDRO-1,2-DIHYDROXYBENZOATE
DEHYDROGENASE) (DHB DEHYDROGENASE)
>gi|151722|gb|AAA26050.1| (M64747)
1,2-dihydroxycyclohexa-3,4-diene carboxylate
dehydrogenase [Plasmid pWW0]
Length = 269
Score = 77.3 bits (187), Expect = 2e-13
Identities = 73/259 (28%), Positives = 118/259 (45%), Gaps = 16/259 (6%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GK+A T +++GIG VA +A G ++++ R+E + A E + EV + ADL
Sbjct: 7 GKVAVITGAAQGIGRRVAERMAAEGGRLLLVDRSELIHELADELV---GVAEVLTLTADL 63
Query: 68 TKMDDLERTVKE-LKNIGEPDIFFFSTGGP---KPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ + +R + L+ G DI + GG KP F + E V+ L+P ++
Sbjct: 64 EQFAECQRVMAAALERFGRLDILINNVGGTIWAKP--FEHYQEREIEAEVRRSLFPTLWC 121
Query: 124 TKALVPAMERKGFGRIIYSTSVAIK--EPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
A + M +G G I+ +SVA + +P A V L LA E +GI
Sbjct: 122 CHAALAPMIEQGSGAIVNVSSVATRGIHRVPYGAAKGGVN----ALTACLAFETAERGIR 177
Query: 182 VNGIMPGIIRTDRM-IQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN PG + + + +++E ++ + + + R G +E + FLA
Sbjct: 178 VNATAPGGTEARHGGFRNSAEPSEQEKVWYQQIVDQSLDSSLMKRYGSIDEQVEAILFLA 237
Query: 241 SDLGSYINGAMIPVDGGRL 259
SD SYI G +PV GG L
Sbjct: 238 SDAASYITGITLPVAGGDL 256
>sp|P22441|DHMA_FLAS1 N-ACYLMANNOSAMINE 1-DEHYDROGENASE (NAM-DH) >gi|279966|pir||A43744
N-acylmannosamine 1-dehydrogenase (EC 1.1.1.233) -
Flavobacterium sp. (strain 141-8)
>gi|216705|dbj|BAA14346.1| (D90316) N-acyl-D-mannosamine
dehydrogenase [Flavobacterium sp.]
Length = 271
Score = 77.3 bits (187), Expect = 2e-13
Identities = 75/267 (28%), Positives = 110/267 (41%), Gaps = 25/267 (9%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L+GK A T ++ GIG + GA V+ + + A + +E + + +A
Sbjct: 13 LAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAP---RLAATRYEEPGAIPIACDLA 69
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFS---TGGPKPGYFMEMSMEDWEEAVKLLLYPAIY 122
D +D + +G DI GG G F+++S DW+ V + +
Sbjct: 70 DRAAID--AAMADAVARLGGLDILVAGGALKGGT--GNFLDLSDADWDRYVDVNMTGTFL 125
Query: 123 LTKALVPAMERKGFG------RIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELG 176
+A AM G G RII SV P A + +A L R +A +L
Sbjct: 126 TCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLA 185
Query: 177 PKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLV 236
GI VN I PG + + E + E+ L E A LGR G PEE+
Sbjct: 186 RHGILVNMIAPGPVDVT-----GNNTGYSEPRLAEQVLDEVA----LGRPGLPEEVATAA 236
Query: 237 AFLASDLGSYINGAMIPVDGGRLNSVF 263
FLA D S+I G+ I +DGG +F
Sbjct: 237 VFLAEDGSSFITGSTITIDGGLSAMIF 263
>pir||S23485 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase (EC
1.3.1.25) - Pseudomonas putida plasmid pWW0
Length = 257
Score = 77.3 bits (187), Expect = 2e-13
Identities = 73/259 (28%), Positives = 118/259 (45%), Gaps = 16/259 (6%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADL 67
GK+A T +++GIG VA +A G ++++ R+E + A E + EV + ADL
Sbjct: 7 GKVAVITGAAQGIGRRVAERMAAEGGRLLLVDRSELIHELADELV---GVAEVLTLTADL 63
Query: 68 TKMDDLERTVKE-LKNIGEPDIFFFSTGGP---KPGYFMEMSMEDWEEAVKLLLYPAIYL 123
+ + +R + L+ G DI + GG KP F + E V+ L+P ++
Sbjct: 64 EQFAECQRVMAAALERFGRLDILINNVGGTIWAKP--FEHYQEREIEAEVRRSLFPTLWC 121
Query: 124 TKALVPAMERKGFGRIIYSTSVAIK--EPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
A + M +G G I+ +SVA + +P A V L LA E +GI
Sbjct: 122 CHAALAPMIEQGSGAIVNVSSVATRGIHRVPYGAAKGGVN----ALTACLAFETAERGIR 177
Query: 182 VNGIMPGIIRTDRM-IQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN PG + + + +++E ++ + + + R G +E + FLA
Sbjct: 178 VNATAPGGTEARHGGFRNSAEPSEQEKVWYQQIVDQSLDSSLMKRYGSIDEQVEAILFLA 237
Query: 241 SDLGSYINGAMIPVDGGRL 259
SD SYI G +PV GG L
Sbjct: 238 SDAASYITGITLPVAGGDL 256
>gb|AAF05840.1|AF197058_1 (AF197058) trans-2-enoyl-ACP reductase [Staphylococcus aureus]
Length = 256
Score = 76.9 bits (186), Expect = 2e-13
Identities = 72/265 (27%), Positives = 119/265 (44%), Gaps = 22/265 (8%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
ML ++ + A+ + I FGVA+VL + GA ++ R E + K + +++ + E
Sbjct: 1 MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA 60
Query: 61 HYIVADLTKMDDLERTVKEL-KNIGEPDIFF----FSTGGPKPGYFMEMSMEDWEEAVKL 115
H D+ +++ +++ K++G D + F+ G F E S E + A +
Sbjct: 61 HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI 120
Query: 116 LLYP---AIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLA 172
Y + K L+P G I+ +T + + + N + V + ++ V+ LA
Sbjct: 121 SSYSLTIVAHEAKKLMPE-----GGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLA 175
Query: 173 KELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEI 232
+LGP I VN I G IRT AK G L+E + PL R + E+
Sbjct: 176 LDLGPDNIRVNAISAGPIRT--------LSAKGVG-GFNTILKEIEERAPLKRNVDQVEV 226
Query: 233 GYLVAFLASDLGSYINGAMIPVDGG 257
G A+L SDL S + G I VD G
Sbjct: 227 GKTAAYLLSDLSSGVTGENIHVDSG 251
>emb|CAA74944.1| (Y14603) sorbitol-6-phosphate dehydrogenase [Erwinia amylovora]
Length = 259
Score = 76.5 bits (185), Expect = 3e-13
Identities = 67/257 (26%), Positives = 112/257 (43%), Gaps = 8/257 (3%)
Query: 9 KLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHY----IV 64
++A + +G + LA+AG V + NE N R + I Y
Sbjct: 3 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 62
Query: 65 ADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
D ++ L R V E G D+ +S G K + + D++ ++++ L +
Sbjct: 63 TDEASVEALARAVDE--TFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCS 120
Query: 125 KALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+ M R G GRII S + K + + + + GL ++LA +L GITV+
Sbjct: 121 REFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVH 180
Query: 184 GIMPGIIRTDRMIQ-LAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASD 242
+M G + M Q L A++ G T EE Y +PL R + +++ ++ F ASD
Sbjct: 181 SLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASD 240
Query: 243 LGSYINGAMIPVDGGRL 259
+Y G I V GG++
Sbjct: 241 KAAYCTGQSINVTGGQV 257
>sp|Q22230|YVX3_CAEEL HYPOTHETICAL OXIDOREDUCTASE T05C12.3 >gi|7507170|pir||T24510
hypothetical protein T05C12.3 - Caenorhabditis elegans
>gi|3879451|emb|CAA91310.1| (Z66500) contains similarity
to Pfam domain: PF00106 (short chain dehydrogenase),
Score=122.3, E-value=2.9e-33, N=1; PF00678 (Short chain
dehydrogenase/reductase C-terminus), Score=35.3,
E-value=8.5e-09, N=1~cDNA EST yk252b4.3 comes from this
gene [Cae>
Length = 309
Score = 76.5 bits (185), Expect = 3e-13
Identities = 73/257 (28%), Positives = 114/257 (43%), Gaps = 11/257 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L GK+A T GIG +A A GA V I +R E L++ E+I + +
Sbjct: 23 LKGKVALVTGGGTGIGKAIATTFAHLGASVAIAARRMEKLEQTAEEIMKTTGGICEPFRM 82
Query: 66 DLTKMDDLERTVKEL-KNIGE-PDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYL 123
D+ + T ++ K G+ PDI + G +S + ++L + +
Sbjct: 83 DIKDPGMVSDTFDKIDKKFGKHPDILVNNAAGNFIMATERLSPNAHGTIIDIVLKGTMNV 142
Query: 124 TKALVPAMERKGFGRIIYSTSVAI-KEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITV 182
T L + G + S + A + P I S V + + + ++LA E G+
Sbjct: 143 TTELGKRCIQSKTGASVTSITAAYARSGAPFIVPSAVSKAGVEIMTKSLATEWSKYGLRF 202
Query: 183 NGIMPGIIRTDRMIQLAQDRA-KREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
N + PG I T A R E V E ++E P GR G PEE+ LVAF++S
Sbjct: 203 NAVSPGPIPTKG----AWGRLFSGEMGDVAEKMKELN---PEGRSGTPEEVANLVAFISS 255
Query: 242 DLGSYINGAMIPVDGGR 258
D S++NG +I +DGG+
Sbjct: 256 DHMSFMNGVIIDLDGGQ 272
>pir||S07135 ribitol 2-dehydrogenase (EC 1.1.1.56) - Klebsiella pneumoniae
>gi|149319|gb|AAA25140.1| (M25606) ribitol dehydrogenase
rbtD [Klebsiella aerogenes]
Length = 249
Score = 76.1 bits (184), Expect = 4e-13
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 19/241 (7%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ LSGK+A T ++ GIG AR L AGA V+++ R E L K+ E
Sbjct: 8 MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLN----KLVAELGENAF 63
Query: 62 YIVADLTKMDDLERTVKELKNI-GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ DL + D ++ ++ + + G DIF + G G E + W+ + L + A
Sbjct: 64 ALQVDLMQADQVDNLLQGILQLTGRLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAA 123
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
++++P + + G II+++S+A P+ + + A+ V T +++ G+
Sbjct: 124 FRCVRSVLPHLIAQKSGDIIFTSSIAGVVPVIWEPVYTASKFAVQAFVHTTRRQVAQYGV 183
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
V ++PG + T L D K + ++EAL G L +P E+ V F+
Sbjct: 184 RVGAVLPGPVVT----ALLDDWPKAK---MDEALAN-------GSLMQPIEVAESVLFMV 229
Query: 241 S 241
+
Sbjct: 230 T 230
>sp|P55541|Y4LA_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Y4LA
>gi|7431041|pir||T10877 y4lA protein - Rhizobium sp.
(strain NGR234) plasmid pNGR234a
>gi|2182500|gb|AAB91754.1| (AE000082) Y4lA [Rhizobium
sp. NGR234]
Length = 278
Score = 76.1 bits (184), Expect = 4e-13
Identities = 65/258 (25%), Positives = 116/258 (44%), Gaps = 18/258 (6%)
Query: 8 GKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESN--VEVHYIVA 65
GK+A T + GIG A +A+ G V++ + +I E+ + + +A
Sbjct: 6 GKVAVVTGAGAGIGKACALAIAREGGRVVVADLDGSAAIACTAQIAAEAGNALAMAMDIA 65
Query: 66 DLTKMDDLERTVKELKNIGEPDIFFFSTGG----PKPGYFMEMSMEDWEEAVKLLLYPAI 121
D + L T + ++ G D+ + P+ +++ + W++ + L +
Sbjct: 66 DAQAVAALFETAE--RHFGGVDLLVNNASAMHLTPRDRAILDLDLAVWDQTMATNLRGTL 123
Query: 122 YLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGIT 181
+ +P M +G G I+ +S V + AM L +LA + G I
Sbjct: 124 LCCRQAIPRMIARGGGAIVNMSSCQGLSGDTAQTSYAVSKAAMNMLSASLATQYGHAQIR 183
Query: 182 VNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLAS 241
N + PG+I T+R++ AK + K ++ L + L R+G PE++ LVAFL S
Sbjct: 184 CNAVAPGLIMTERLL------AKLD-KCMQRHLSRHQL---LPRVGHPEDVAALVAFLLS 233
Query: 242 DLGSYINGAMIPVDGGRL 259
D S+I G ++ +DGG L
Sbjct: 234 DDASFITGQVVCIDGGML 251
>emb|CAC11881.1| (AL445065) glucose 1-dehydrogenase related protein [Thermoplasma
acidophilum]
Length = 245
Score = 74.9 bits (181), Expect = 9e-13
Identities = 66/251 (26%), Positives = 115/251 (45%), Gaps = 17/251 (6%)
Query: 14 TASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTK-MDD 72
T S+GIG +A LAK GA+++I + ++ + + V+ H + D + +
Sbjct: 3 TGGSRGIGRAIALGLAKQGANILISYASHDSEADEVLETASKYGVKAHKVKVDQSDPYES 62
Query: 73 LERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKALVPAM- 131
+ K ++ G+ I + G F +S++ +E+ K+ + ++T+ + M
Sbjct: 63 IRFAEKAIETFGKVHILVDNAGICPFEDFFRISVDLFEKVWKVNVESHYFITQRIAKNMI 122
Query: 132 ERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMPGIIR 191
E K GRI+ +S++ + A+ G + ++A LG GI VN + PG I
Sbjct: 123 ENKINGRILLISSISAHVGGEFQTHYTTTKSALNGFMHSIAIVLGKYGILVNSLEPGTIL 182
Query: 192 TD---RMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLASDLGSYIN 248
TD + + RA E +TV +GRLG PE++ FL SD +Y+
Sbjct: 183 TDINKEDLSNQEKRAYMERRTV------------VGRLGLPEDMVAPALFLLSDDNTYVT 230
Query: 249 GAMIPVDGGRL 259
G + DGG L
Sbjct: 231 GTELLADGGML 241
>pir||T06212 glucose and ribitol dehydrogenase homolog - barley
>gi|633890|gb|AAC60580.1| (S72926) glucose and ribitol
dehydrogenase homolog [Hordeum vulgare]
Length = 293
Score = 74.5 bits (180), Expect = 1e-12
Identities = 74/267 (27%), Positives = 116/267 (42%), Gaps = 27/267 (10%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIIL------SRNEENLKRAREKIKEESNV- 58
L GK+A T GIG V LA GA V ++ E +A IK +
Sbjct: 38 LQGKVALVTGGDSGIGRAVCLCLALEGATVNFTYVKGHEDKDAEETLQALRDIKSRTGAG 97
Query: 59 EVHYIVADLTKMDDLERTVKELKNI--GEPDIFFFSTGGP--KPGYFMEMSMEDWEEAVK 114
E + DL ++ R V+E+ N G DI + +P E++ +D E +
Sbjct: 98 EPKALSGDLGYEENCRRVVEEVANAHGGRVDILVNNAAEQYVRP-CITEITEQDLERVFR 156
Query: 115 LLLYPAIYLTKALVPAMERKGFGR-IIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAK 173
++ +TK V M G G II +TSV + + + A+ R L+
Sbjct: 157 TNIFSYFLMTKFAVKHM---GPGSSIINTTSVNAYKGNATLLDYTATKGAIVAFTRALSM 213
Query: 174 ELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIG 233
+L KGI VNG+ PG I T + EE ++++ +P+ R G+P E+
Sbjct: 214 QLAEKGIRVNGVAPGPIWTPLI----------PASFPEEKVKQFGSEVPMKRAGQPSEVA 263
Query: 234 YLVAFLASDL-GSYINGAMIPVDGGRL 259
FLAS+ SYI+G ++ +GG +
Sbjct: 264 PSFVFLASEQDSSYISGQILHPNGGTI 290
>emb|CAB91875.1| (AJ277945) putative alcohol dehydrogenase [Lycopersicon esculentum]
Length = 259
Score = 74.5 bits (180), Expect = 1e-12
Identities = 70/260 (26%), Positives = 121/260 (45%), Gaps = 17/260 (6%)
Query: 3 KIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHY 62
K+ L GK+A T ++ GIG AR+ + GA V++ +E ++ + I + + Y
Sbjct: 4 KLRLEGKVAIITGAASGIGEASARLFVEHGARVVVADIQDELGQKVVDSIGSD---KASY 60
Query: 63 IVADLTKMDDLERTVK-ELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
D+T +E TV ++ G DI F + G ++M + ++E + + + +
Sbjct: 61 RHCDVTDEKQVEETVAYAVEKYGTLDIMFSNVGTLNFCSVLDMDVLAFDETMAINVRGSA 120
Query: 122 YLTKALVPAM-ERKGFGRIIYSTSV-AIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKG 179
K M ++K G II + S+ I ++A + A+ G+++ A+ELGP G
Sbjct: 121 LAVKHAAKVMVDKKIRGSIICNASLEGILAGAASLAYI-ASKHAVVGIIKAAARELGPHG 179
Query: 180 ITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEAL--QEYAKPIPLGRLGEPEEIGYLVA 237
I VNG+ P I T L + +EEA+ + K + L + +
Sbjct: 180 IRVNGVSPYGIAT----PLVTKAYGLDAALLEEAIYGNGHLKGVKLSTM----HVAQSAL 231
Query: 238 FLASDLGSYINGAMIPVDGG 257
FLASD +Y +G + VDGG
Sbjct: 232 FLASDESAYTSGQNLAVDGG 251
>dbj|BAB01821.1| (AB026657) alcohol dehydrogenase-like protein [Arabidopsis
thaliana]
Length = 296
Score = 74.5 bits (180), Expect = 1e-12
Identities = 69/262 (26%), Positives = 117/262 (44%), Gaps = 16/262 (6%)
Query: 1 MLKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEV 60
M + L GK+A T + GIG R+ GA V+I+ EE + I + +
Sbjct: 37 MSGLRLDGKIAIITGGASGIGAEAVRLFTDHGAKVVIVDIQEELGQNLAVSIGLD---KA 93
Query: 61 HYIVADLTKMDDLERTVK-ELKNIGEPDIFFFSTGGPKP-GYFMEMSMEDWEEAVKLLLY 118
+ ++T D+E VK ++ G+ D+ F + G + G +++ +E ++ + + +
Sbjct: 94 SFYRCNVTDETDVENAVKFTVEKHGKLDVLFSNAGVLEAFGSVLDLDLEAFDRTMAVNVR 153
Query: 119 PAIYLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGP 177
A K +M G G I+ +TS+A + P + A+ GL+R+ LG
Sbjct: 154 GAAAFIKHAARSMVASGTRGSIVCTTSIAAEIGGPGPHSYTASKHALLGLIRSACAGLGQ 213
Query: 178 KGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIP--LGRLGEPEEIGYL 235
GI VNG+ P + T ++ K L+EY + + G + + I
Sbjct: 214 YGIRVNGVAPYGVATGMTSAYNEEAVK--------MLEEYGEALGNLKGVVLKARHIAEA 265
Query: 236 VAFLASDLGSYINGAMIPVDGG 257
FLASD YI+G + VDGG
Sbjct: 266 ALFLASDDSVYISGQNLVVDGG 287
>pir||S07134 ribitol 2-dehydrogenase (EC 1.1.1.56) - Klebsiella pneumoniae
Length = 249
Score = 74.1 bits (179), Expect = 2e-12
Identities = 60/241 (24%), Positives = 109/241 (44%), Gaps = 19/241 (7%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ LSGK+A T ++ GIG AR L AGA V+++ R E L K+ E
Sbjct: 8 MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKL----NKLVAELGENAF 63
Query: 62 YIVADLTKMDDLERTVKELKNI-GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ DL + D ++ ++ + + G DIF + G G E + W+ + L + A
Sbjct: 64 ALQVDLMQADQVDNLLQGILQLTGRLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAA 123
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
++++P + + G II++ +A P+ + + A+ V T +++ G+
Sbjct: 124 FRCVRSVLPHLIAQKSGDIIFTAVIAGVVPVIWEPVYTASKFAVQAFVHTTRRQVAQYGV 183
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
V ++PG + T L D K + ++EAL + G L +P E+ V F+
Sbjct: 184 RVGAVLPGPVVT----ALLDDWPKAK---MDEALAD-------GSLMQPIEVAESVLFMV 229
Query: 241 S 241
+
Sbjct: 230 T 230
>pir||B70640 hypothetical protein Rv0687 - Mycobacterium tuberculosis (strain
H37RV) >gi|1806153|emb|CAB06450.1| (Z84395) hypothetical
protein Rv0687 [Mycobacterium tuberculosis]
Length = 275
Score = 74.1 bits (179), Expect = 2e-12
Identities = 81/275 (29%), Positives = 119/275 (42%), Gaps = 30/275 (10%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILS-------------RNEENLKRAREKI 52
L G++AF T +++ G A LA+ GAD++ L E+L +
Sbjct: 8 LHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGSVTYPPATSEDLGETVRAV 67
Query: 53 KEESNVEVHYIVADLTKMDDLERTVKE-LKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEE 111
+ E +V D+ +L R V + ++ G DI + G G E++ E WE
Sbjct: 68 EAEGR-KVLAREVDIRDDAELRRLVADGVEQFGRLDIVVANAGVLGWGRLWELTDEQWET 126
Query: 112 AVKLLLYPAIYLTKALVPAMERKGFGR--IIYSTSVAIKEPIPNIALSNVVRIAMAGLVR 169
+ + L +A VPAM G G ++ S+S +K P + A+ L
Sbjct: 127 VIGVNLTGTWRTLRATVPAMIDAGNGGSIVVVSSSAGLKAT-PGNGHYAASKHALVALTN 185
Query: 170 TLAKELGPKGITVNGIMPGIIRTDRMIQ---LAQDRAKREGKTVEEALQEYAKPIPLGRL 226
TLA ELG GI VN I P + T MI+ + Q AK G P+PL
Sbjct: 186 TLAIELGEFGIRVNSIHPYSVDTP-MIEPEAMIQTFAKHPGYV------HSFPPMPLQPK 238
Query: 227 G--EPEEIGYLVAFLASDLGSYINGAMIPVDGGRL 259
G P+EI +V +LA D ++G IPVD G L
Sbjct: 239 GFMTPDEISDVVVWLAGDGSGALSGNQIPVDKGAL 273
>sp|Q29529|CBR2_PIG LUNG CARBONYL REDUCTASE [NADPH] (NADPH-DEPENDENT CARBONYL
REDUCTASE) (LCR) >gi|543092|pir||JN0703 carbonyl
reductase (NADPH) (EC 1.1.1.184) - pig
>gi|416425|dbj|BAA03963.1| (D16511) carbonyl reductase
[Sus scrofa]
Length = 244
Score = 73.7 bits (178), Expect = 2e-12
Identities = 63/261 (24%), Positives = 118/261 (45%), Gaps = 18/261 (6%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
++++ SG A T + KGIG + L +GA V+ ++R +L ++ +
Sbjct: 1 MQMNFSGLRALVTGAGKGIGRDTVKALHVSGARVVAVTRTNGDLVSLSQECP-----GIE 55
Query: 62 YIVADLTKMDDLERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAI 121
+ DL D E T + L +G D+ + F++ + E ++ + + L
Sbjct: 56 PVCVDL---GDWEATERALGGVGPVDLLVNNAAVALMQPFLDTTKEVFDRSFNVNLRSVF 112
Query: 122 YLTKALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
+++ + +M +G G I+ +S+ P +A + + AM L +++A ELGP I
Sbjct: 113 QVSQIVARSMIERGVPGSIVNVSSMVSHVTYPGLAAYSSTKGAMTMLTKSMAMELGPHKI 172
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
VN + P ++ T A R+ + L+E P+ + E E++ + FL
Sbjct: 173 RVNSVNPTVVLT------AMGRSVTSDPELARKLKERH---PMRKFAEVEDVVNSILFLL 223
Query: 241 SDLGSYINGAMIPVDGGRLNS 261
SD + +G+ I VD G L S
Sbjct: 224 SDRSASTSGSSIFVDAGYLAS 244
>emb|CAC11623.1| (AL445064) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 654
Score = 73.7 bits (178), Expect = 2e-12
Identities = 72/260 (27%), Positives = 117/260 (44%), Gaps = 11/260 (4%)
Query: 6 LSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVA 65
L G + T ++ GIG + LA+ VI + R RE ++E+ V V
Sbjct: 400 LLGSIGLVTGAASGIGLEAMKKLAENECTVIGCDIDPSITDRCRE-VEEQYGVRAIPFVV 458
Query: 66 DLTKMDD-LERTVKELKNIGEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPAIYLT 124
DL+ L+ + ++ +G DI F + G K +E S+ED + ++ + +
Sbjct: 459 DLSSESQILDMFGQFVREVGGLDILFNNAGILKSSKIVETSVEDLDRHYAIIGRASFITS 518
Query: 125 KALVPAMERKGF-GRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVN 183
+ + M +G G I+Y+ S + P P + + A + +AKE G GI N
Sbjct: 519 REAMKIMISQGIGGNIVYNISKNLTHPGPEMVSYGSAKAFAAQVCHYVAKEGGRYGIRAN 578
Query: 184 GIMPG-IIRTDRMIQ--LAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEI-GYLVAFL 239
I P I R ++ + + + RAK +G+TVE EY L R P + L+A +
Sbjct: 579 IINPDKIFRGSKIWENGVLEARAKAKGQTVE----EYVTGNLLRREVLPSHVANMLLAMV 634
Query: 240 ASDLGSYINGAMIPVDGGRL 259
D+ AM+PVDGG L
Sbjct: 635 NEDIFGATTDAMVPVDGGIL 654
>sp|P00335|RIDH_KLEAE RIBITOL 2-DEHYDROGENASE (RDH)
Length = 249
Score = 73.4 bits (177), Expect = 3e-12
Identities = 60/241 (24%), Positives = 108/241 (43%), Gaps = 19/241 (7%)
Query: 2 LKIDLSGKLAFTTASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVH 61
+ LSGK+A T ++ GIG AR L AGA V+++ R E L K+ E
Sbjct: 8 MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKL----NKLVAELGENAF 63
Query: 62 YIVADLTKMDDLERTVKELKNI-GEPDIFFFSTGGPKPGYFMEMSMEDWEEAVKLLLYPA 120
+ DL + D ++ ++ + + G DIF + G G E + W+ + L + A
Sbjct: 64 ALQVDLMQADQVDNLLQGILQLTGRLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAA 123
Query: 121 IYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGI 180
++++P + + G II++ +A P+ + + A+ V T +++ G+
Sbjct: 124 FRCVRSVLPHLIAQKSGDIIFTAVIAGVVPVIWEPVYTASKFAVQAFVHTTRRQVAQYGV 183
Query: 181 TVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPIPLGRLGEPEEIGYLVAFLA 240
V ++PG + T L D K + ++EAL G L +P E+ V F+
Sbjct: 184 RVGAVLPGPVVT----ALLDDWPKAK---MDEALAN-------GSLMQPIEVAESVLFMV 229
Query: 241 S 241
+
Sbjct: 230 T 230
>pir||S75500 short-chain alcohol dehydrogenase-related protein, 26K -
Synechocystis sp. (strain PCC 6803)
>gi|1653145|dbj|BAA18061.1| (D90911) short-chain alcohol
dehydrogenase family [Synechocystis sp.]
Length = 249
Score = 73.4 bits (177), Expect = 3e-12
Identities = 47/159 (29%), Positives = 80/159 (49%), Gaps = 3/159 (1%)
Query: 102 MEMSMEDWEEAVKLLLYPAIYLTKALVPAMERKGFGRIIYSTSVAIKEPIPNIALSNVVR 161
+E S++DW++ + + L A L K P +++ G I+ +SV NIA +
Sbjct: 87 LETSLDDWDQVMAVNLRAAFLLAKMSHPYLQQT-HGSIVNISSVHALATSANIASYAASK 145
Query: 162 IAMAGLVRTLAKELGPKGITVNGIMPGIIRTDRMIQLAQDRAKREGKTVEEALQEYAKPI 221
+ L R +A E I VN ++PG + T M++ R ++ + LQE
Sbjct: 146 GGLIALTRAMAIEWAADQIRVNALLPGAVNTP-MLREGLSRGHLVEQSPQHQLQELGSKT 204
Query: 222 PLGRLGEPEEIGYLVAFLA-SDLGSYINGAMIPVDGGRL 259
+GR+G+P EI +AFLA ++ S++ G I +DGG +
Sbjct: 205 VMGRVGQPSEIAQAIAFLADNEQSSFMTGQTITIDGGAI 243
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.138 0.384
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89807324
Number of Sequences: 2977
Number of extensions: 3655157
Number of successful extensions: 15081
Number of sequences better than 1.0e-10: 566
Number of HSP's better than 0.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 533
Number of HSP's that attempted gapping in prelim test: 14062
Number of HSP's gapped (non-prelim): 572
length of query: 263
length of database: 189,106,746
effective HSP length: 57
effective length of query: 206
effective length of database: 154,992,987
effective search space: 31928555322
effective search space used: 31928555322
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 164 (68.3 bits)