BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB2178 (pepq-1) DE:x-pro dipeptidase
         (365 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75217 x-pro dipeptidase PAB2178 - Pyrococcus abyssi (strai...   728  0.0
pir||D71204 hypothetical protein PH1902 - Pyrococcus horikoshii ...   681  0.0
emb|CAC11625.1| (AL445064) proline dipeptidase related protein [...   278  8e-74
pir||T46973 X-Pro dipeptidase (EC 3.4.13.9), cobalt dependent [v...   143  3e-33
pir||E75088 cobalt-dependent proline dipeptidase (pepq-2) PAB163...   139  4e-32
pir||G71056 probable X-Pro dipeptidase - Pyrococcus horikoshii >...   139  5e-32
pir||C75134 x-pro aminopeptidase (pepq-3) PAB1781 - Pyrococcus a...   105  7e-22
pir||C70433 probable X-Pro dipeptidase (EC 3.4.13.9) - Aquifex a...   104  1e-21
pir||G72425 hypothetical protein TM0042 - Thermotoga maritima (s...   102  6e-21
dbj|BAB06898.1| (AP001518) prolidase (proline dipeptidase) [Baci...   102  8e-21
sp|Q58216|Y806_METJA HYPOTHETICAL PEPTIDASE MJ0806 >gi|2129355|p...    99  5e-20
gb|AAK40693.1| Prolidase (Xaa-Pro dipeptidase) (pepQ) [Sulfolobu...    96  8e-19
pir||A71089 probable dipeptidase - Pyrococcus horikoshii >gi|325...    93  4e-18
sp|Q10698|YK89_MYCTU PROBABLE DIPEPTIDASE RV2089C >gi|7445465|pi...    93  5e-18
sp|P46545|PEPQ_LACDL XAA-PRO DIPEPTIDASE (X-PRO DIPEPTIDASE) (PR...    90  5e-17
emb|CAA70068.1| (Y08842) aminopeptidase P [Lactococcus lactis]         89  6e-17
sp|O84913|PEPQ_LACHE XAA-PRO DIPEPTIDASE (X-PRO DIPEPTIDASE) (PR...    89  8e-17
emb|CAB07978.1| (Z93944) prolidase [Lactobacillus delbrueckii]         89  1e-16
pir||G69869 Xaa-Pro dipeptidase homolog ykvY - Bacillus subtilis...    88  1e-16
sp|Q9S6S1|PEPQ_LACDE XAA-PRO DIPEPTIDASE (X-PRO DIPEPTIDASE) (PR...    88  1e-16
sp|P54518|YQHT_BACSU PUTATIVE PEPTIDASE IN GCVT-SPOIIIAA INTERGE...    87  3e-16
emb|CAC12166.1| (AL445066) proline dipeptidase related protein [...    86  5e-16
pir||A72750 probable Xaa-Pro dipeptidase APE0526 - Aeropyrum per...    84  2e-15
gb|AAD53120.1|AF176799_2 (AF176799) PepQ [Lactobacillus pentosus]      82  1e-14
dbj|BAB06519.1| (AP001516) Xaa-Pro dipeptidase [Bacillus halodur...    80  4e-14
gb|AAG19202.1| (AE005016) probable peptidase; PepQ1 [Halobacteri...    77  3e-13
pir||H71496 probable aminopeptidase P - Chlamydia trachomatis (s...    74  2e-12
emb|CAB93372.1| (AL357523) putative peptidase [Streptomyces coel...    74  2e-12
gb|AAK40375.1| X-pro aminopeptidase [Sulfolobus solfataricus]          74  3e-12
gb|AAC46293.1| (AF014460) PepQ [Streptococcus mutans]                  73  4e-12
pir||B72032 proline dipeptidase CP1058 [imported] - Chlamydophil...    73  4e-12
pir||D75419 proline dipeptidase - Deinococcus radiodurans (strai...    73  4e-12
pir||F72247 methionine aminopeptidase - Thermotoga maritima (str...    72  9e-12
pir||T47008 hypothetical protein [imported] - Yersinia pestis >g...    72  1e-11
sp|P55666|Y4TL_RHISN HYPOTHETICAL HYDROLASE/PEPTIDASE Y4TL >gi|2...    71  3e-11
emb|CAB07979.1| (Z93945) prolidase-related protein [Lactobacillu...    71  3e-11

>pir||B75217 x-pro dipeptidase PAB2178 - Pyrococcus abyssi (strain Orsay)
           >gi|5457694|emb|CAB49185.1| (AJ248283) x-pro dipeptidase
           [Pyrococcus abyssi]
           Length = 365
           
 Score =  728 bits (1858), Expect = 0.0
 Identities = 365/365 (100%), Positives = 365/365 (100%)

Query: 1   MVMDVNKMRGNKEIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAE 60
           MVMDVNKMRGNKEIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAE
Sbjct: 1   MVMDVNKMRGNKEIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAE 60

Query: 61  GEPTVLVVKGEAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAY 120
           GEPTVLVVKGEAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAY
Sbjct: 61  GEPTVLVVKGEAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAY 120

Query: 121 LIFYKIFLRLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGK 180
           LIFYKIFLRLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGK
Sbjct: 121 LIFYKIFLRLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGK 180

Query: 181 SELEIAAEVVRELMLNGSEDPKVYVSVTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYA 240
           SELEIAAEVVRELMLNGSEDPKVYVSVTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYA
Sbjct: 181 SELEIAAEVVRELMLNGSEDPKVYVSVTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYA 240

Query: 241 NMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHL 300
           NMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHL
Sbjct: 241 NMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHL 300

Query: 301 AGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDK 360
           AGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDK
Sbjct: 301 AGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDK 360

Query: 361 LERVT 365
           LERVT
Sbjct: 361 LERVT 365


>pir||D71204 hypothetical protein PH1902 - Pyrococcus horikoshii
           >gi|3258344|dbj|BAA31027.1| (AP000007) 365aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 365
           
 Score =  681 bits (1737), Expect = 0.0
 Identities = 335/365 (91%), Positives = 353/365 (95%)

Query: 1   MVMDVNKMRGNKEIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAE 60
           MVM  NKMRG+K+IFKKRVERFQELL+ENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAE
Sbjct: 1   MVMRGNKMRGDKKIFKKRVERFQELLKENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAE 60

Query: 61  GEPTVLVVKGEAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAY 120
           GEP VLVVKGEAELFK+RSWIEDVVEYQK EELM TVVKWI++N MKRVGLEFGIERDAY
Sbjct: 61  GEPRVLVVKGEAELFKERSWIEDVVEYQKAEELMLTVVKWIRENEMKRVGLEFGIERDAY 120

Query: 121 LIFYKIFLRLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGK 180
           LIFYKIFLRLNP++EVVDILDLTM LRMIKDEWEL+NIRKAGKIALKGMRVAEEEIKPG+
Sbjct: 121 LIFYKIFLRLNPTVEVVDILDLTMKLRMIKDEWELDNIRKAGKIALKGMRVAEEEIKPGR 180

Query: 181 SELEIAAEVVRELMLNGSEDPKVYVSVTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYA 240
           +ELEIAAEV RELMLNGSEDPKVYVSVTPRAHAEPFRDLKVPENG+VTVVIGTDWNHYYA
Sbjct: 181 TELEIAAEVTRELMLNGSEDPKVYVSVTPRAHAEPFRDLKVPENGVVTVVIGTDWNHYYA 240

Query: 241 NMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHL 300
           NMARTFI+GDPGERVKKAIEVKKEA+KLALEET+VGVPIS VEKKIE FFKERGFG+YHL
Sbjct: 241 NMARTFIIGDPGERVKKAIEVKKEAIKLALEETKVGVPISTVEKKIEQFFKERGFGDYHL 300

Query: 301 AGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDK 360
           +GYTHGVGLLIEEPPIATIVVPQRA +IQENMVLSIIHPPLMLPEGAIKYENTYIVKKD 
Sbjct: 301 SGYTHGVGLLIEEPPIATIVVPQRAAKIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDG 360

Query: 361 LERVT 365
           LERVT
Sbjct: 361 LERVT 365


>emb|CAC11625.1| (AL445064) proline dipeptidase related protein [Thermoplasma
           acidophilum]
           Length = 331
           
 Score =  278 bits (703), Expect = 8e-74
 Identities = 135/321 (42%), Positives = 205/321 (63%), Gaps = 3/321 (0%)

Query: 39  LSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELFKQRSWIEDVVEYQKVEELMATVV 98
           +S+FIY TG KWLRPSL+IPAEG+PTVL+  GE + F++ +WI++V+ Y    +LM  VV
Sbjct: 1   MSTFIYITGIKWLRPSLIIPAEGDPTVLLADGEEDGFREMAWIKNVLSYSDGSQLMGEVV 60

Query: 99  KWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSIEVVDILDLTMSLRMIKDEWELENI 158
           K++KD   K+VG+E+ +ERDA++ FY +F +LN ++EVVDI D+   +++IKD +E++ I
Sbjct: 61  KYLKDLNAKKVGMEYAVERDAFIFFYDLFKKLNRNVEVVDITDILDDIKVIKDRYEIDYI 120

Query: 159 RKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRELMLNGSEDPKVYVSV--TPRAHAEPF 216
            KAG++  K      + ++ G  E +IAAE    L   GSE+P +Y++    PR H+EP 
Sbjct: 121 MKAGEVTRKVAAALADLVREGMKETDIAAEAYYMLYKAGSEEPLIYINAGPNPRVHSEPL 180

Query: 217 RDLKVPENGIVTVVIGTDWNHYYANMARTFIVGDPGERVKKAIEVKKEALKLALEETRVG 276
             + +  N IVT+ +  D++ YY N + T  +G+PG+    AI+   EA K+A+E TR G
Sbjct: 181 STVTIRNNSIVTITLDADFSRYYVNKSLTIPIGNPGDTALNAIKCMDEAQKVAVENTRPG 240

Query: 277 VPISAVEKKIEHFFKERGFGEYHLAGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSI 336
                V +K++  +K+     Y + GY H VGL  EE PI TIV   R   ++  MVL++
Sbjct: 241 TKFIEVMEKLDETYKKYDMLRYRVIGYAHSVGLKPEEMPITTIVPKDRFVEVKPYMVLAL 300

Query: 337 IHPPLMLPE-GAIKYENTYIV 356
            H PLM+P  G++K E TY+V
Sbjct: 301 GHAPLMIPGIGSVKIEETYVV 321


>pir||T46973 X-Pro dipeptidase (EC 3.4.13.9), cobalt dependent [validated] -
           Pyrococcus furiosus (fragment)
           >gi|3372642|gb|AAC61259.1| (AF060010) proline
           dipeptidase [Pyrococcus furiosus]
           Length = 348
           
 Score =  143 bits (357), Expect = 3e-33
 Identities = 105/356 (29%), Positives = 182/356 (50%), Gaps = 22/356 (6%)

Query: 16  KKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELF 75
           K+R+E+  + + EN+ID   I    +  YF+GT  L    +I    E T+ V + E E+ 
Sbjct: 2   KERLEKLVKFMDENSIDRVFIAKPVNVYYFSGTSPLGGGYIIVDGDEATLYVPELEYEMA 61

Query: 76  KQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSIE 135
           K+ S +  VV+++K +E    + + +K+          GIE        + F   +   E
Sbjct: 62  KEESKLP-VVKFKKFDE----IYEILKNTET------LGIEGTLSYSMVENFKEKSNVKE 110

Query: 136 VVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRELML 195
              I D+   LR+IK + E+E I KA +IA K +  A EEI  GK E E+AA+V   + +
Sbjct: 111 FKKIDDVIKDLRIIKTKEEIEIIEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKM 170

Query: 196 NGSEDPKVYVSVTPRAHAEPF-----RDLKVPENGIVTVVIGTDWNHYYANMARTFIVGD 250
           NG+E P  + ++    H          D ++    +V + +G  +NHY +++ RT +VG 
Sbjct: 171 NGAEKP-AFDTIIASGHRSALPHGVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGS 229

Query: 251 PGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVGLL 310
           P E+ ++  E+  EA K A+E  + G+    ++       KE G+G+Y +    HGVGL 
Sbjct: 230 PNEKQREIYEIVLEAQKRAVEAAKPGMTAKELDSIAREIIKEYGYGDYFIHSLGHGVGLE 289

Query: 311 IEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDKLERVT 365
           I E P    +     T ++E MV++ I P + +P+ G ++ E+T ++ ++  +R+T
Sbjct: 290 IHEWP---RISQYDETVLKEGMVIT-IEPGIYIPKLGGVRIEDTVLITENGAKRLT 341


>pir||E75088 cobalt-dependent proline dipeptidase (pepq-2) PAB1637 - Pyrococcus
           abyssi (strain Orsay) >gi|5458522|emb|CAB50010.1|
           (AJ248286) cobalt-dependent proline  dipeptidase
           (pepQ-2) [Pyrococcus abyssi]
           Length = 351
           
 Score =  139 bits (348), Expect = 4e-32
 Identities = 104/360 (28%), Positives = 174/360 (47%), Gaps = 26/360 (7%)

Query: 14  IFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAE 73
           I  ++++R  E + EN+ID  +I    +  Y +G   L    ++      T+ V + E E
Sbjct: 3   IMDEKIKRIIEFMNENSIDAVLITKNPNIYYLSGASPLAGGYILVNNDGATLYVPELEYE 62

Query: 74  LFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPS 133
           + K+ S I   VE  K  +    V + +K           GIE      F +        
Sbjct: 63  MAKEESKIP--VEKFKRRDDFYKVFEGVK---------VLGIEGSLSYSFVEDLKEKGKI 111

Query: 134 IEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVREL 193
            E   + D+   +R++K + E++ I KA +IA K +  A EE+  GK E EIAA+V   +
Sbjct: 112 SEFKKVDDVIKEMRIVKSDEEIKIIEKACEIADKAVMAAIEEVTEGKKEREIAAKVEYLM 171

Query: 194 MLNGSEDPKV-------YVSVTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTF 246
            +NG+E P         Y S  P   A    D ++ +  +V + +G  +NHY +++ RT 
Sbjct: 172 KMNGAEKPAFDTIIASGYRSALPHGVAS---DKRIEKGDLVVIDLGALYNHYNSDITRTV 228

Query: 247 IVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHG 306
           +VG P E+ ++  E+  EA K A+E  R G+    ++    +  KE G+G+Y +    HG
Sbjct: 229 VVGSPNEKQREIYEIVLEAQKKAVEAARPGITTKELDSIARNIIKEYGYGDYFIHSLGHG 288

Query: 307 VGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDKLERVT 365
           VGL I E P    V     T ++E MV++ I P + +P+ G ++ E+T ++ K    R+T
Sbjct: 289 VGLEIHEWP---GVSQYDETVLKEGMVIT-IEPGIYIPKFGGVRIEDTIVITKTGARRLT 344


>pir||G71056 probable X-Pro dipeptidase - Pyrococcus horikoshii
           >gi|3257566|dbj|BAA30249.1| (AP000005) 351aa long
           hypothetical X-Pro dipeptidase [Pyrococcus horikoshii]
           Length = 351
           
 Score =  139 bits (347), Expect = 5e-32
 Identities = 103/361 (28%), Positives = 182/361 (49%), Gaps = 26/361 (7%)

Query: 13  EIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEA 72
           +I  ++V++  E + +N+ID  +I    +  Y +G   L    ++      T+ V + E 
Sbjct: 2   DIMNEKVKKIIEFMDKNSIDAVLIAKNPNVYYISGASPLAGGYILITGESATLYVPELEY 61

Query: 73  ELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNP 132
           E+ K+ S I  V +++K++E    +       G+K +G+E  +    Y    ++  + N 
Sbjct: 62  EMAKEESNIP-VEKFKKMDEFYKAL------EGIKSLGIESSLP---YGFIEELKKKANI 111

Query: 133 SIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRE 192
             E   + D+   +R+IK E E++ I KA +IA K +  A EEI  GK E E+AA+V   
Sbjct: 112 K-EFKKVDDVIRDMRIIKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYL 170

Query: 193 LMLNGSEDPKV-------YVSVTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMART 245
           + +NG+E P         Y S  P   A    D ++    +V + +G  + HY +++ RT
Sbjct: 171 MKMNGAEKPAFDTIIASGYRSALPHGVAS---DKRIERGDLVVIDLGALYQHYNSDITRT 227

Query: 246 FIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTH 305
            +VG P E+ K+  E+  EA K A+E  + G+    ++    +   E G+GEY      H
Sbjct: 228 IVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGH 287

Query: 306 GVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDKLERV 364
           GVGL + E P    V     T ++E MV++ I P + +P+ G ++ E+T ++ K+  +R+
Sbjct: 288 GVGLEVHEWP---RVSQYDETVLREGMVIT-IEPGIYIPKIGGVRIEDTILITKNGSKRL 343

Query: 365 T 365
           T
Sbjct: 344 T 344


>pir||C75134 x-pro aminopeptidase (pepq-3) PAB1781 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458299|emb|CAB49788.1| (AJ248285) X-pro
           aminopeptidase (pepQ-3) [Pyrococcus abyssi]
           Length = 355
           
 Score =  105 bits (260), Expect = 7e-22
 Identities = 101/356 (28%), Positives = 163/356 (45%), Gaps = 34/356 (9%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWL----RPSLLI-PAEGEPTVLVVKGEA 72
           R++RF +LL E N DGA I   S+  Y TG K      RP++L+  A+GE  +L     +
Sbjct: 2   RIDRFVKLLNEMNFDGAFISPGSNLYYLTGLKLHEVGERPTILVVSADGEYKLLAPSLYS 61

Query: 73  EL---FKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLR 129
            +   F    W +    Y K+  ++  +  +       R  +E  +  D  +   K+   
Sbjct: 62  NVITNFPVTFWRDGENPYAKLSTILGELKLY-----RGRFLVEDTMRADWLIGILKL--- 113

Query: 130 LNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIK---PGKSELEIA 186
              + E   +  L   +RM KD  E+EN++ A +IA K   V EE +     G SE E+A
Sbjct: 114 --GNFEFHPLSSLIRLMRMRKDREEIENMKHAARIADK---VFEEILSWDILGMSEKELA 168

Query: 187 AEV---VRELMLNGSEDPKVYVSV-TPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANM 242
            ++   +REL    S  P V     +   H EP  + K+ +  IV +  G  W  Y +++
Sbjct: 169 LKIEVRIRELSDGVSFSPIVASGENSANPHHEP-GERKIRKGDIVILDYGARWRGYCSDI 227

Query: 243 ARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAG 302
            RT  VG P E++ +  E+ KEA + A    R G+    V+K       E G+GEY    
Sbjct: 228 TRTIAVGRPDEKLIEVYEIVKEAQEKAYRAVREGIKAKEVDKVAREVISEAGYGEYFTHR 287

Query: 303 YTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVK 357
             HG+GL + E P    + P     ++  M  + I P + +P  G ++ E+  +V+
Sbjct: 288 TGHGLGLDVHEEP---YIGPDGEVTLENGMTFT-IEPGIYIPGLGGVRIEDDVVVE 339


>pir||C70433 probable X-Pro dipeptidase (EC 3.4.13.9) - Aquifex aeolicus
           >gi|2983896|gb|AAC07447.1| (AE000744) xaa-pro
           dipeptidase [Aquifex aeolicus]
           Length = 354
           
 Score =  104 bits (258), Expect = 1e-21
 Identities = 93/350 (26%), Positives = 164/350 (46%), Gaps = 24/350 (6%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELFKQ 77
           +V+  QEL++E N+D  +  +  +  Y +  +      +I  + E  +L      E  K 
Sbjct: 2   KVKEVQELIKEKNLDAFMFSSQPNVFYLSRFRSTNAYAVITPQ-EKYLLTDARYYERAKN 60

Query: 78  RSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSIEVV 137
           +    +VV  +    L  +V  ++++ G+K VG E     D     +K  L+ +  I  V
Sbjct: 61  QLKDWEVVLIKG--NLFKSVKNFLREKGLKYVGYE----EDRVSCTFKKHLK-SKHIRWV 113

Query: 138 DILDLTMSLRMIKDEWEL----ENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVREL 193
              +   ++R++K + E+    E +RK+ KI     R     +KPG +EL++   +V ++
Sbjct: 114 GFSNFLKNVRVLKTKEEISIMKEGVRKSDKI----YRELLNFVKPGMTELQVRGFIVSKI 169

Query: 194 MLNGSED---PKVYVSVTPRA--HAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTFIV 248
                E    P +  S    A  H E  R+ K+ EN  + + +G  W  Y  +  RTF +
Sbjct: 170 FEKNGEGESFPAIVASGEHSAVPHWESSRE-KIKENAPLLIDMGLLWEGYCTDFTRTFHI 228

Query: 249 GDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVG 308
           G P E  +K  E+ KEA   ALE+ +VG  +  V++    + +++G+G++      HGVG
Sbjct: 229 GKPSEEFRKVYEIVKEAHLRALEKAKVGNTVGDVDRAAREYIEKKGYGQFFTHSTGHGVG 288

Query: 309 LLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYENTYIVK 357
           + I E P          T I+E MV + I P + LP +  ++ EN   V+
Sbjct: 289 VEIHEFPRVYYKGDDAKTPIEEGMVFT-IEPGIYLPGKFGVRLENIVAVQ 337


>pir||G72425 hypothetical protein TM0042 - Thermotoga maritima (strain MSB8)
           >gi|4980527|gb|AAD35136.1|AE001691_10 (AE001691)
           aminopeptidase P, putative [Thermotoga maritima]
           Length = 359
           
 Score =  102 bits (252), Expect = 6e-21
 Identities = 90/357 (25%), Positives = 165/357 (46%), Gaps = 18/357 (5%)

Query: 18  RVERFQELLRENNIDGAVIRTL-----SSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEA 72
           R ER  +L+ E  ID  +I  +     +S +YF+G       +LI    E T L++    
Sbjct: 3   RSERLIQLISEEGIDAFLIMNIENSARASSVYFSGFTGSFSIILI---SENTRLLITDSR 59

Query: 73  ELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNP 132
              + +   +  V   K  + +  + K + D  +K + LE   ER +  +F +I      
Sbjct: 60  YTVQAKQETDFEVREVKGGDFIDVLKKTVNDLKIKTIALEE--ERVSLSLFRRISSAFGD 117

Query: 133 SIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRE 192
             + + I D    +RM+KDE E+E I++A +I+ +      ++I+ G +E EIAA +   
Sbjct: 118 R-KFIGIDDEVKQMRMVKDEGEIEKIKQAIEISERAFLETVQQIRAGMTEKEIAALLEYT 176

Query: 193 LMLNGSED---PKVYVSVTPRAHAEPFRDLKVPENGIVTVV-IGTDWNHYYANMARTFIV 248
           +   G+E      +  S    A        KV E G V V+  G  + +Y A++ R   +
Sbjct: 177 MRKEGAEGVAFDTIVASGCRSALPHGKASDKVVERGDVIVIDFGATYENYCADITRVVSI 236

Query: 249 GDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVG 308
           G+P + VK+   +  EA + AL+  + GV    ++     F +E+G+GE+      HG+G
Sbjct: 237 GEPSDEVKEVHSIVLEAQERALKIAKAGVTGKLLDSVAREFIREKGYGEFFGHSLGHGIG 296

Query: 309 LLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDKLERVT 365
           L + E P  +    +  + + EN+V ++     +  +  I+ E   ++K+   E +T
Sbjct: 297 LEVHEGPAISF---RNDSPLPENVVFTVEPGIYLEGKFGIRIEEDVVLKEQGCEILT 350


>dbj|BAB06898.1| (AP001518) prolidase (proline dipeptidase) [Bacillus halodurans]
           Length = 364
           
 Score =  102 bits (251), Expect = 8e-21
 Identities = 91/363 (25%), Positives = 164/363 (45%), Gaps = 24/363 (6%)

Query: 17  KRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRP-----SLLIPAEGEPTVLVVKGE 71
           +R++R  E L++N+   A I+  +S  Y TG  +  P     SLL+  E EP ++    E
Sbjct: 2   ERIKRVIEWLKDNDHSMAFIQDKTSIFYLTGF-YCDPHERLVSLLLFPEAEPCLICPNME 60

Query: 72  AELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLN 131
             L K+  W  +++ Y  +E+    V + ++    KR  +      +A  + Y     L 
Sbjct: 61  TSLVKEAGWTGEILGYSDIEDPWLLVRQAVE----KRNAVLTSCIVEAPRLTYARVQALQ 116

Query: 132 ---PSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAE 188
              P+I+++D     M LR  K   EL  +++A  +A  G+ V  + I+ G+SE+EI A 
Sbjct: 117 DAFPAIKLIDGEPFLMELRKQKSAKELTTLKEAAALADYGVEVGVQAIQEGRSEIEILAL 176

Query: 189 VVRELMLNGSEDPKVYVSV-----TPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMA 243
           +  EL   G  D      V     +   H  P     + +   V   +G   + Y +++ 
Sbjct: 177 IEYELKRKGVRDMSFGTLVLSGDQSANPHGNP-GQRTIKKGDFVLFDLGVVLDGYCSDIT 235

Query: 244 RTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGY 303
           RT       ++ +   E  ++A + AL+  R GV I  +++       E G+G+Y     
Sbjct: 236 RTVAFHHVTDQQQDIYETVRKAQQAALDACRPGVEIRTLDQIARTIITEAGYGDYFPHRI 295

Query: 304 THGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDKLE 362
            HG+G+ + E P           R+Q+ MV + I P + LP  G ++ E+  ++ +D  +
Sbjct: 296 GHGLGMEVHELPSLN---ETNTDRLQKGMVFT-IEPGIYLPSIGGVRIEDDVVITEDGYQ 351

Query: 363 RVT 365
            +T
Sbjct: 352 TLT 354


>sp|Q58216|Y806_METJA HYPOTHETICAL PEPTIDASE MJ0806 >gi|2129355|pir||F64400 X-Pro
           dipeptidase (EC 3.4.13.9) - Methanococcus jannaschii
           >gi|1591498|gb|AAB98806.1| (U67525) X-pro aminopeptidase
           (pepQ) [Methanococcus jannaschii]
           Length = 347
           
 Score = 99.5 bits (244), Expect = 5e-20
 Identities = 97/362 (26%), Positives = 177/362 (48%), Gaps = 37/362 (10%)

Query: 13  EIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEA 72
           +I   R+ERF + +    I  AVI    +  YF G  ++  S+L+  E +P + V K + 
Sbjct: 7   DIMNNRIERFLKYMESEGIKKAVILKKENINYFLGKYFMSFSVLV-FEEQPYLYVGKLDK 65

Query: 73  ELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNP 132
           +  ++     ++ E++  EE+                G + G+E++  + + K   +   
Sbjct: 66  DYAEEHFNFLEIREFKSWEEIFK--------------GCD-GVEKELSIGYLKYIDK--- 107

Query: 133 SIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGK--SELEIAAEVV 190
             E   I D    +RMIKD+ E++ I+KA +I+ K +      +   K  +E E+ AE+ 
Sbjct: 108 --EYKIISDKIKEMRMIKDKEEIKLIKKAAEISDKAINWVLNNLDEVKNLTEYELVAEIE 165

Query: 191 RELMLNGSEDP---KVYVS--VTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMART 245
             +  +GS  P    + VS   T   HA P +D K+ +  I+ V IG  +  Y +++ RT
Sbjct: 166 YIMKKHGSIKPAFDSIVVSGKKTSFPHALPTKD-KIAD--ILLVDIGAVYEGYCSDITRT 222

Query: 246 FIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTH 305
           F++ D  E +KK   +  EA K+A E  + G+    ++  +  FF +  + E  +    H
Sbjct: 223 FLLKD-DEEMKKIYNLVYEAKKVAEEHLKEGISAKQIDNIVREFFND--YKELFIHSLGH 279

Query: 306 GVGLLI-EEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEG-AIKYENTYIVKKDKLER 363
           GVGL + EEP ++  +       ++E MV++ I P L L +   ++ E+ Y+VKK+  E+
Sbjct: 280 GVGLEVHEEPRLSNKLKDDEDIILKEGMVVT-IEPGLYLKDKFGVRIEDLYLVKKNGFEK 338

Query: 364 VT 365
           ++
Sbjct: 339 LS 340


>gb|AAK40693.1| Prolidase (Xaa-Pro dipeptidase) (pepQ) [Sulfolobus solfataricus]
           Length = 352
           
 Score = 95.6 bits (234), Expect = 8e-19
 Identities = 86/348 (24%), Positives = 156/348 (44%), Gaps = 14/348 (4%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELFKQ 77
           R+ + + +L +     A+I    +  YF   ++     LI  +   T+LV   E    + 
Sbjct: 3   RLRKLKAILEDKKDSCAIIFGSPNLFYFL--EYSGAGALIYCDSRFTLLVPALEMYRAEN 60

Query: 78  RSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSIEVV 137
              ++  + Y    +++  V++      ++++  +  I  D   +    +  L+   +V+
Sbjct: 61  VKDVDIAIYYPS--KILENVIEGNIFRAIEKIVNKSNIMLDVSWVEASTYKALSEKYKVI 118

Query: 138 DILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKS-ELEIAAEVVRELMLN 196
           D  +  + LR +KD  E+E IRKAG+I    M++  E++  G S E ++A  +   +   
Sbjct: 119 DFSNEIVRLREVKDNDEIERIRKAGEITAVAMKIGMEKLSEGTSNEKQVAGIIDMTMRSM 178

Query: 197 GSED---PKVYVSVTPRAHAEPF-RDLKVPENGIVTVVIGTDWNHYYANMARTFIVGDPG 252
           G+ED   P +       A+      D  +  N IV   IG  +N Y  +  RTF+     
Sbjct: 179 GAEDYAFPSIVAFGENSAYPHHIPTDRVLGNNDIVLFDIGAKYNGYCFDSTRTFVF--KN 236

Query: 253 ERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVGLLIE 312
              KK  EV  EA   A++  R GV  S V+       ++ G+G+Y +    HGVG+ I 
Sbjct: 237 SEAKKVYEVVLEAQMEAIDAVRDGVMASEVDITARRVIEKAGYGKYFIHSTGHGVGVEIH 296

Query: 313 EPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDK 360
           E P  ++   Q    ++ENM++++     +     I+ E+T IV K K
Sbjct: 297 ESPAVSMNSKQ---ILKENMIITVEPGIYLKGRFGIRIEDTLIVTKGK 341


>pir||A71089 probable dipeptidase - Pyrococcus horikoshii
           >gi|3257388|dbj|BAA30071.1| (AP000004) 356aa long
           hypothetical dipeptidase [Pyrococcus horikoshii]
           Length = 356
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 91/361 (25%), Positives = 157/361 (43%), Gaps = 28/361 (7%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPS-----LLIPAEGEPTVL---VVK 69
           R+E+F  LL E   DGA+I   ++  Y TG +          L + AEG+   L   + +
Sbjct: 2   RLEKFIHLLGERGFDGALISPGTNLYYLTGLRLHEVGERLAILAVSAEGDYRFLAPSLYE 61

Query: 70  GEAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLR 129
                F    W +    Y K+ E++  +          R+ +E  +  D  +   K+   
Sbjct: 62  NVVNNFPATFWHDGENPYAKLREILEEL-----GISKGRILIEDTMRADWLIGIMKL--- 113

Query: 130 LNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEV 189
                    +  L   LRMIKD+ E++ +  A +IA K           G  E E+A ++
Sbjct: 114 --GKFTFQPLSSLIKELRMIKDKEEVKMMEHASRIADKVFEEILTWDLIGMKERELALKI 171

Query: 190 ---VRELMLNGSEDPKVYVSVTP-RAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMART 245
              +REL    + +P V         H EP  + K+ +  I+ +  G  W  Y +++ RT
Sbjct: 172 ELLIRELSDGIAFEPIVASGENAANPHHEP-GERKIRKGDIIILDYGARWKGYCSDITRT 230

Query: 246 FIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTH 305
             +G+  ER+ K  EV K+A + A +  R G+    V+ +      + G+GEY +    H
Sbjct: 231 IGLGELDERLVKIYEVVKDAQESAFKAVREGIKAKDVDSRAREVISKAGYGEYFIHRTGH 290

Query: 306 GVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDKLERV 364
           G+GL + E P    + P     ++  M  + I P + +P  G ++ E+  +V + K  R+
Sbjct: 291 GLGLDVHEEP---YIGPDGEVILKNGMTFT-IEPGIYVPGLGGVRIEDDIVVDEGKGRRL 346

Query: 365 T 365
           T
Sbjct: 347 T 347


>sp|Q10698|YK89_MYCTU PROBABLE DIPEPTIDASE RV2089C >gi|7445465|pir||D70767 probable pepQ
           - Mycobacterium tuberculosis (strain H37RV)
           >gi|1370256|emb|CAA98201.1| (Z73966) pepE [Mycobacterium
           tuberculosis]
           Length = 375
           
 Score = 92.8 bits (227), Expect = 5e-18
 Identities = 88/342 (25%), Positives = 151/342 (43%), Gaps = 32/342 (9%)

Query: 9   RGNKEIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLR----PSLLIPAEGEPT 64
           R + E++ +R+        +  + G VI       Y  G++        +L++PA G P 
Sbjct: 5   RFDAEVYARRLALAAAATADAGLAGLVITPGYDLCYLIGSRAETFERLTALVLPAAGAPA 64

Query: 65  VLVVKGEAELFKQRSWIEDVVEYQKVEELMATVVKWIK-DNGMKRVGLEFGIERDAYLIF 123
           V++ + E    KQ +            EL   V  W+  D+    V    G    A  + 
Sbjct: 65  VVLPRLELAALKQSA----------AAELGLRVCDWVDGDDPYGLVSAVLGGAPVATAVT 114

Query: 124 YKI----FLRLNPSIEVVDIL--DLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIK 177
             +     L L  ++ V+ +L  D+   LRM+K+E E++ +RKAG    +      E + 
Sbjct: 115 DSMPALHMLPLADALGVLPVLATDVLRRLRMVKEETEIDALRKAGAAIDRVHARVPEFLV 174

Query: 178 PGKSELEIAAEVVRELMLNG-SEDPKVYVSVTPRAHAEP---FRDLKVPENGIVTVVIGT 233
           PG++E ++AA++   ++  G SE   V V   P   A+P   + D ++ E  IV V IG 
Sbjct: 175 PGRTEADVAADIAEAIVAEGHSEVAFVIVGSGPHG-ADPHHGYSDRELREGDIVVVDIGG 233

Query: 234 DWNH-YYANMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKE 292
            +   Y+++  RT+ +G+P   V ++  + + A + A E  R GV    V+        E
Sbjct: 234 TYGPGYHSDSTRTYSIGEPDSDVAQSYSMLQRAQRAAFEAIRPGVTAEQVDAAARDVLAE 293

Query: 293 RGFGEYHLAGYTHGVGLLIEEPPIAT-----IVVPQRATRIQ 329
            G  EY +    HG+GL + E P        ++VP  A  I+
Sbjct: 294 AGLAEYFVHRTGHGIGLCVHEEPYIVAGNDLVLVPGMAFSIE 335


>sp|P46545|PEPQ_LACDL XAA-PRO DIPEPTIDASE (X-PRO DIPEPTIDASE) (PROLINE DIPEPTIDASE)
           (PROLIDASE) (IMIDODIPEPTIDASE) >gi|1075982|pir||S52202
           X-Pro dipeptidase (EC 3.4.13.9) [validated] -
           Lactobacillus delbrueckii >gi|609078|emb|CAA84379.1|
           (Z34896) prolidase [Lactobacillus delbrueckii]
           >gi|1150454|emb|CAA90911.1| (Z54205) prolidase PepQ
           [Lactobacillus delbrueckii]
           Length = 368
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 80/360 (22%), Positives = 161/360 (44%), Gaps = 20/360 (5%)

Query: 19  VERFQELLRENNIDGAVIRTLSSFIYFTG----TKWLRPSLLIPAEGEPTVLVVKGEAEL 74
           +++ Q  L+EN +D A + + ++  YFTG     +     L    + EP +       E 
Sbjct: 3   LDKLQNWLQENGMDVAYVSSPTTINYFTGFITDPEERIFKLFAFKDAEPFLFCPALNYEE 62

Query: 75  FKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLI--FYKIFLRLNP 132
            K  +W  DVV Y   E+  + + + IK     +    + +E++   +  +  +  +   
Sbjct: 63  AKASAWDGDVVGYLDSEDPWSKIAEEIKKR--TKDYQNWAVEKNGLTVAHYQALHAQFPD 120

Query: 133 SIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRE 192
           S    D+ D    +R+ K E EL  +RKAG+ A    ++  E ++ G +E  + +++  +
Sbjct: 121 SDFSKDLSDFIAHIRLFKTESELVKLRKAGEEADFAFQIGFEALRNGVTERAVVSQIEYQ 180

Query: 193 LMLNGSEDPKVYVSVTPRA------HAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTF 246
           L L        + ++          H  P  +   P N +V   +GT    Y ++ +RT 
Sbjct: 181 LKLQKGVMQTSFDTIVQAGKNAANPHQGPSMNTVQP-NELVLFDLGTMHEGYASDSSRTV 239

Query: 247 IVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHG 306
             G+P +++++  EV + A + A++  + G+  S ++        + G+GEY +    HG
Sbjct: 240 AYGEPTDKMREIYEVNRTAQQAAIDAAKPGMTASELDGVARKIITDAGYGEYFIHRLGHG 299

Query: 307 VGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGA-IKYENTYIVKKDKLERVT 365
           +G+ + E P    +       ++E M  S I P + +P  A ++ E+  ++ KD  +  T
Sbjct: 300 IGMEVHEFP---SIANGNDVVLEEGMCFS-IEPGIYIPGFAGVRIEDCGVLTKDGFKPFT 355


>emb|CAA70068.1| (Y08842) aminopeptidase P [Lactococcus lactis]
           Length = 352
           
 Score = 89.3 bits (218), Expect = 6e-17
 Identities = 76/356 (21%), Positives = 163/356 (45%), Gaps = 22/356 (6%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELFKQ 77
           R+E+ +  +   NID  +I  + +  Y TG      ++ +  +      +   ++   + 
Sbjct: 2   RIEKLKVKMLTENIDSLLITDMKNIFYLTGFSGTAGTVFLTQKRN----IFMTDSRYSEM 57

Query: 78  RSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSIEVV 137
              +    E  +  + ++ + +      +K +  E  ++       Y  F RL+ +   +
Sbjct: 58  ARGLIKNFEIIETRDPISLLTELSASESVKNMAFEETVD-------YAFFKRLSKAATKL 110

Query: 138 DIL---DLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEV---VR 191
           D+    +  + LR IKDE E+  I+KA +IA +    A   I+PG++E+E+A  +   +R
Sbjct: 111 DLFSTSNFVLELRQIKDESEISLIKKACEIADEAFMSALRFIEPGRTEIEVANFLDFKMR 170

Query: 192 ELMLNGSEDPKVYVSVTPRAHAEPFRDLKVPENGI-VTVVIGTDWNHYYANMARTFIVGD 250
           +L  +G     +  S    +        K+ + G  VT+  G  + HY ++M RT  VG 
Sbjct: 171 DLEASGISFETIVASGKRSSLPHGVATSKMIQFGDPVTIDFGCYYEHYASDMTRTIFVGS 230

Query: 251 PGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVGLL 310
             ++++   E  ++A +  +++ + G+  +  +       ++  FG+Y   G  HG+GL 
Sbjct: 231 VDDKMRTIYETVRKANEALIKQVKAGMTYAQYDNIPREVIEKADFGQYFTHGIGHGLGLD 290

Query: 311 IEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDKLERVT 365
           + E P     + +   +++  MV++   P + LPE G ++ E+  +V ++  E +T
Sbjct: 291 VHEIPYFNQSMTE--NQLRSGMVIT-DEPGIYLPEFGGVRIEDDLLVTENGCEVLT 343


>sp|O84913|PEPQ_LACHE XAA-PRO DIPEPTIDASE (X-PRO DIPEPTIDASE) (PROLINE DIPEPTIDASE)
           (PROLIDASE) (IMIDODIPEPTIDASE)
           >gi|3282339|gb|AAC24966.1| (AF012084) prolidase
           [Lactobacillus helveticus]
           Length = 368
           
 Score = 88.9 bits (217), Expect = 8e-17
 Identities = 87/363 (23%), Positives = 160/363 (43%), Gaps = 26/363 (7%)

Query: 19  VERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRP-----SLLIPAEGEPTVLVVKGEAE 73
           +++ Q+ L+++N D A I    +  YFTG   + P     +LL+  +  P +       E
Sbjct: 3   LDKLQQWLQDSNNDIAYISNPITISYFTGYS-MDPHERIFALLVFKDANPFIFCPALNVE 61

Query: 74  LFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVG--LEFGIERDAYLIFYKIFLRLN 131
             K   W  DV  Y   E+      + I DN  KR      + IE+D   + +  +LR  
Sbjct: 62  EAKNSEWNGDVFGYLDSEDPW----ELIADNVRKRTSDTHTWAIEKDDLSVAHYQYLRGE 117

Query: 132 -PSIEVV-DILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEV 189
            P+     D+      LR+ K   E++ ++ AG  A    ++  + I+ G +E  IA ++
Sbjct: 118 FPNASFTNDVSSFIERLRLYKTPEEIKKLQGAGAEADFAFKIGFDAIRTGVTERSIAGQI 177

Query: 190 VRELMLNGSEDPKVYVSVTPRA------HAEPFRDLKVPENGIVTVVIGTDWNHYYANMA 243
             +L +      + + ++          H  P  +   P N +V   +GT  + Y ++ +
Sbjct: 178 DYQLKIQKGVMHESFETIVQAGKNAANPHLGPTMNTVQP-NELVLFDLGTMHDGYASDSS 236

Query: 244 RTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGY 303
           RT   G P ++ ++  EV +EA + A+E  + G+    ++        + G+GEY +   
Sbjct: 237 RTVAYGTPSDKQREIYEVDREAQQAAIEAAKPGITAEELDSVARDIITKAGYGEYFIHRL 296

Query: 304 THGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGA-IKYENTYIVKKDKLE 362
            HG+G  + E P    +V      ++E M  S I P + +P  A ++ E+  +V KD  +
Sbjct: 297 GHGIGKNVHEYP---SIVQGNDLVLEEGMCFS-IEPGIYIPGFAGVRIEDCGVVTKDGFK 352

Query: 363 RVT 365
             T
Sbjct: 353 TFT 355


>emb|CAB07978.1| (Z93944) prolidase [Lactobacillus delbrueckii]
           Length = 368
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 79/360 (21%), Positives = 159/360 (43%), Gaps = 20/360 (5%)

Query: 19  VERFQELLRENNIDGAVIRTLSSFIYFTG----TKWLRPSLLIPAEGEPTVLVVKGEAEL 74
           +++ Q  L+EN +D A + + ++  YFTG     +     L    + EP +       E 
Sbjct: 3   LDKLQNWLQENGMDVAYVSSPTTINYFTGFITDPEERIFKLFAFKDAEPFLFCPALNYEE 62

Query: 75  FKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLI--FYKIFLRLNP 132
            K  +W  DVV Y   E+    + + IK          + +E++   +  +  +  +   
Sbjct: 63  AKASAWDGDVVGYLDSEDPWGKIAEEIKQRSKDYQN--WAVEKNGLTVAHYQALHAQFPD 120

Query: 133 SIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRE 192
           S    D+ D    +R+ K E EL  +RKAG+ A    ++  E ++ G +E  + +++  +
Sbjct: 121 SDFSKDLSDFIAHIRLFKTESELVKLRKAGEEADFAFQIGFEALRNGVTERAVVSQIEYQ 180

Query: 193 LMLNGSEDPKVYVSVTPRA------HAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTF 246
           L L        + ++          H  P  +   P N +V   +GT    Y ++ +RT 
Sbjct: 181 LKLQKGVMQTSFDTIVQAGKNAANPHQGPSMNTVQP-NELVLFDLGTMHEGYASDSSRTV 239

Query: 247 IVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHG 306
             G+P +++++  EV + A + A++  + G+  S ++        + G+GEY +    HG
Sbjct: 240 AYGEPTDKMREIYEVNRTAQQAAIDAAKPGMTASELDGVARKIITDAGYGEYFIHRLGHG 299

Query: 307 VGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGA-IKYENTYIVKKDKLERVT 365
           +G+ + E P    +       ++E M  S I P + +P  A ++ E+  ++ K+  +  T
Sbjct: 300 IGMEVHEFP---SIANGNDVVLEEGMCFS-IEPGIYIPGFAGVRIEDCGVLTKEGFKPFT 355


>pir||G69869 Xaa-Pro dipeptidase homolog ykvY - Bacillus subtilis
           >gi|2633757|emb|CAB13259.1| (Z99111) similar to Xaa-Pro
           dipeptidase [Bacillus subtilis]
           Length = 363
           
 Score = 88.2 bits (215), Expect = 1e-16
 Identities = 85/354 (24%), Positives = 152/354 (42%), Gaps = 20/354 (5%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRP-----SLLIPAEGEPTVLVVKGEA 72
           R++R    L+E     A I T  +  Y TG  +  P      L I  E EP  +    EA
Sbjct: 3   RIQRVSSWLKEAGHTAAFIHTKENVFYLTGF-YTEPHERLMGLFIFQEEEPFFVCPGMEA 61

Query: 73  ELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLR-LN 131
              +   W  +++ Y   E     + K +K   +    L   +E+D+  +     L+   
Sbjct: 62  GQARNAGWNHEIIGYADHENPWELIEKALKKRNISIHML--AVEKDSISLSRAEQLKHAT 119

Query: 132 PSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVR 191
              + V   +     R+IKD+ E+  +++A K+A  G+ V    ++ G SE+E+ A++  
Sbjct: 120 GGAQFVSAEETLNQFRLIKDDNEIRLLKEAAKLADYGVEVGTAALREGISEVEVLAQIEY 179

Query: 192 ELMLNGSEDPKVYVSV-----TPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTF 246
           EL   G +       V     + + H  P     + +   V   +G   + Y +++ RTF
Sbjct: 180 ELKKKGIQGMSFSTMVLFGEKSGQPHGNP-GTATLKKGDFVLFDLGVILDGYCSDITRTF 238

Query: 247 IVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHG 306
                  + +   E   +A K A+E ++ GV I  ++       ++ G+G+Y      HG
Sbjct: 239 AYKTINPKQEAIYETVLQAEKAAIEASKPGVRIGDLDLTARGIIEKAGYGDYFPHRLGHG 298

Query: 307 VGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKD 359
           +G+ + E P  +       T +QE MV + I P + +PE G ++ E+   V KD
Sbjct: 299 LGISVHEYPSMS---QANDTLLQEGMVYT-IEPGIYVPEIGGVRIEDDVHVTKD 348


>sp|Q9S6S1|PEPQ_LACDE XAA-PRO DIPEPTIDASE (X-PRO DIPEPTIDASE) (PROLINE DIPEPTIDASE)
           (PROLIDASE) (IMIDODIPEPTIDASE)
           >gi|3821250|emb|CAA73815.1| (Y13385) proline dipeptidase
           [Lactobacillus delbrueckii subsp. bulgaricus]
           Length = 368
           
 Score = 88.2 bits (215), Expect = 1e-16
 Identities = 79/360 (21%), Positives = 160/360 (43%), Gaps = 20/360 (5%)

Query: 19  VERFQELLRENNIDGAVIRTLSSFIYFTG----TKWLRPSLLIPAEGEPTVLVVKGEAEL 74
           +++ Q  L+EN +D A + + ++  YFTG     +     L    + EP +       E 
Sbjct: 3   LDKLQNWLQENGMDVAYVSSPTTINYFTGFITDPEERIFKLFAFKDAEPFLFCPALNYEE 62

Query: 75  FKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLI--FYKIFLRLNP 132
            K  +W  DVV Y   E+    + + IK     +    + +E++   +  +  +  +   
Sbjct: 63  AKASAWDGDVVGYLDSEDPWGKIAEEIKQR--TKDYQNWAVEKNGLTVAHYQALHAQFPD 120

Query: 133 SIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRE 192
           S    D+ D    +R+ K E EL  +RKAG+ A    ++  E ++ G +E  + +++  +
Sbjct: 121 SDFSKDLSDFIAHIRLFKTESELVKLRKAGEEADFAFQIGFEALRNGVTERAVVSQIEYQ 180

Query: 193 LMLNGSEDPKVYVSVTPRA------HAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTF 246
           L L        + ++          H  P  +   P N +V   +GT    Y ++ +RT 
Sbjct: 181 LKLQKGVMQTSFDTIVQAGKNAANPHQGPSMNTVQP-NELVLFDLGTMHEGYASDSSRTV 239

Query: 247 IVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHG 306
             G+P +++++  EV + A + A++  + G+  S ++        + G+GEY +    HG
Sbjct: 240 AYGEPTDKMREIYEVNRTAQQAAIDAAKPGMTASELDGVARKIITDAGYGEYFIHRLGHG 299

Query: 307 VGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGA-IKYENTYIVKKDKLERVT 365
           +G+ + E P    +       ++E M  S I P + +P  A ++ E+  ++ K+  +  T
Sbjct: 300 IGMEVHEFP---SIANGNDVVLEEGMCFS-IEPGIYIPGFAGVRIEDCGVLTKEGFKPFT 355


>sp|P54518|YQHT_BACSU PUTATIVE PEPTIDASE IN GCVT-SPOIIIAA INTERGENIC REGION
           >gi|7430115|pir||C69960 Xaa-Pro dipeptidase homolog yqhT
           - Bacillus subtilis >gi|1303901|dbj|BAA12557.1| (D84432)
           YqhT [Bacillus subtilis] >gi|2634880|emb|CAB14377.1|
           (Z99116) similar to Xaa-Pro dipeptidase [Bacillus
           subtilis]
           Length = 353
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 76/362 (20%), Positives = 161/362 (43%), Gaps = 33/362 (9%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELF-- 75
           ++E+ + L  +  IDG +I + ++  Y TG             G   + V+ G+   F  
Sbjct: 2   KLEKLRNLFGQLGIDGMLITSNTNVRYMTGFT-----------GSAGLAVISGDKAAFIT 50

Query: 76  ----KQRSWIEDVVEYQKVEE---LMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFL 128
                +++ ++ V  ++ +E    L+ T    ++  G+KR+G E   +       Y  + 
Sbjct: 51  DFRYTEQAKVQ-VKGFEIIEHGGSLIQTTADTVESFGIKRLGFE---QNSMTYGTYASYS 106

Query: 129 RLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAE 188
            +    E+V + +    LR+IK   E++ + +A KIA    R     +KPG SE+ +A E
Sbjct: 107 AVISDAELVPVAESVEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISEIAVANE 166

Query: 189 VVRELMLNGSEDPKVYVSVTPRAHAE----PFRDLKVPENGIVTVVIGTDWNHYYANMAR 244
           +   +   G++     + V     +        D  +    +VT+  G  +  Y +++ R
Sbjct: 167 LEFYMRSQGADSSSFDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITR 226

Query: 245 TFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYT 304
           T  VG P +++K+  +V  +A  L +   + G+     +         +G+G+Y      
Sbjct: 227 TVAVGQPSDQLKEIYQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTG 286

Query: 305 HGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDKLER 363
           HG+G+ + E P  ++    R++ I E  ++  + P + +PE G ++ E+  ++ ++    
Sbjct: 287 HGLGMEVHESPGLSV----RSSAILEPGMVVTVEPGIYIPETGGVRIEDDIVITENGNRT 342

Query: 364 VT 365
           +T
Sbjct: 343 IT 344


>emb|CAC12166.1| (AL445066) proline dipeptidase related protein [Thermoplasma
           acidophilum]
           Length = 360
           
 Score = 86.2 bits (210), Expect = 5e-16
 Identities = 90/361 (24%), Positives = 156/361 (42%), Gaps = 28/361 (7%)

Query: 19  VERFQELLRENNIDGAVIRTLS------SFIYFTGTK--WLRPSLLIPAEGEPTVLVVKG 70
           VER  E  RE  +D  +I   S      +F Y T T       S LI  +   T+  V  
Sbjct: 3   VERVFEYARE--VDTLLIYNASESARDPTFTYVTQTTNGIFEGSALIVGKNGTTI--VTS 58

Query: 71  EAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRL 130
           + E    R+   DV  ++   +    + + ++D  +  VGL +   +   L  YK+ LR+
Sbjct: 59  QLEEQAARATGLDVRIFKNSTDFQNILRELLRD--VNTVGLNY---QSLSLSSYKMLLRI 113

Query: 131 NPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVV 190
            P  E +D+    +  R IK   EL+ IR+A KI  + +    + +K G +E E+A+++V
Sbjct: 114 VPDKEFLDVSASILEARKIKQAEELKKIREAAKIGSEVLPDVLDSLKEGMTEYEVASKIV 173

Query: 191 RELMLNGSEDPKVYVSV-----TPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMART 245
             +M NG+  P     V         H  P    K+     V +  G  +  Y +++ RT
Sbjct: 174 YLMMKNGASGPSFDTIVAFGQNAAMPHYSP-GQAKLKRGDFVLMDYGARYMGYCSDITRT 232

Query: 246 FIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTH 305
            + G   E  K+     KEA    ++  R G     V+    +      +    +    H
Sbjct: 233 VVFGKATEEQKEMYNTVKEAQAAGMKAIREGANGKDVDAAARNIIDSTKYKGRFIHSLGH 292

Query: 306 GVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYENTYIVKKDKLERV 364
           GVGL + + P  +   P     ++ NMV++ + P + +P  G ++ E+  +V K+  E++
Sbjct: 293 GVGLEVHDHPALS---PTMDFPLKANMVVT-VEPGIYVPGYGGVRIEDDVVVTKEGYEKI 348

Query: 365 T 365
           T
Sbjct: 349 T 349


>pir||A72750 probable Xaa-Pro dipeptidase APE0526 - Aeropyrum pernix  (strain
           K1) >gi|5104177|dbj|BAA79493.1| (AP000059) 349aa long
           hypothetical Xaa-Pro dipeptidase [Aeropyrum pernix]
           Length = 349
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 65/225 (28%), Positives = 106/225 (46%), Gaps = 15/225 (6%)

Query: 142 LTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRELMLNGSEDP 201
           L   +R +K+EWE+  I +A +IA   +R   EE++ G SE E+A  VV  +M +G   P
Sbjct: 119 LISQVRSVKEEWEIGLIAEAARIAEAALRRGIEELREGVSEREVAGAVVDVIMKSGGWGP 178

Query: 202 KVYVSVT-------PRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTFIVGDPGER 254
              V V        P  H     D ++P    V   +G+ +  Y ++M R+   G  G  
Sbjct: 179 SFPVIVAFGGNTALPHHHTG---DARLPHASPVLFDLGSVYKGYMSDMTRSLWRGPGGAE 235

Query: 255 VKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVGLLIEEP 314
            ++  E+  EA   A++    GV    V+K       + GF +Y + G  HGVG+ I E 
Sbjct: 236 YRRLEELVAEAQAEAIDSVAPGVEAWEVDKAARLRLSKEGFSKYFIHGTGHGVGVEIHEN 295

Query: 315 PIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYENTYIVKK 358
           P    + P  +  ++  MV++ I P + LP    ++ E+  +V K
Sbjct: 296 P---YLRPGSSEELKPGMVVT-IEPGVYLPGMYGVRIEDMVLVTK 336


>gb|AAD53120.1|AF176799_2 (AF176799) PepQ [Lactobacillus pentosus]
           Length = 369
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 86/361 (23%), Positives = 150/361 (40%), Gaps = 21/361 (5%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRP-----SLLIPAEGEPTVLVVKGEA 72
           ++++ ++  ++N++D   I    +  Y TG +   P      L + A+ EP +     E 
Sbjct: 6   KLQQVRQWTQDNHVDVTYISNFHTISYLTGFE-SNPYERTLGLFVFADAEPFLFAPALEV 64

Query: 73  ELFKQRSWIEDVVEYQKVEELMATVVKWIKDN--GMKRVGLEFGIERDAYLIFYKIFLRL 130
           E  K+  W   V  Y   E+  A +   I++     K   LE G   +  L  +      
Sbjct: 65  EAIKEMGWPYKVFGYLDHEDPYALIATHIQEQLTDPKSWALEAG---NLTLDRFNALKAQ 121

Query: 131 NPSIEV-VDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEV 189
            P+     D+      LR++K   ELE +  AGK A          +K G++E +IAAE+
Sbjct: 122 FPAAHFDKDLSPYIQQLRLVKTADELEKLNIAGKWADFAFEQGFAAVKAGRTEQQIAAEL 181

Query: 190 VRELMLNGSEDPKVYVSVTPRAHAE----PFRDLKVPENGIVTVVIGTDWNHYYANMART 245
              LM  G  +      V    HA        + +V  N +V   +G  +  Y ++ +RT
Sbjct: 182 QYALMKKGIMEMSFDTLVQAGEHAANPHGATNETQVKPNELVLFDLGVMYEGYASDASRT 241

Query: 246 FIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTH 305
              G P ++ K+  +V  EA   A    + G+    V+K       + G+GEY +    H
Sbjct: 242 IAYGQPTDKQKEIFDVCLEANLTAQAAIKPGMAAEDVDKIARDIITKAGYGEYFIHRLGH 301

Query: 306 GVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGA-IKYENTYIVKKDKLERV 364
           G+G    E P    ++      + E M  S + P + +P  A ++ E+  +V K+  +  
Sbjct: 302 GIGQTDHEFP---SIMAGNHMPLVEGMCFS-VEPGIYIPGVAGVRIEDCGVVTKEGFKPF 357

Query: 365 T 365
           T
Sbjct: 358 T 358


>dbj|BAB06519.1| (AP001516) Xaa-Pro dipeptidase [Bacillus halodurans]
           Length = 355
           
 Score = 80.0 bits (194), Expect = 4e-14
 Identities = 81/315 (25%), Positives = 142/315 (44%), Gaps = 37/315 (11%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIY---FTGTKWLRPSLLIPAEGEPTVLVVKGEAEL 74
           R+ER +  + E++ DG +I +  +  Y   FTGT                 +V  G A  
Sbjct: 3   RLERIRAAIHEHDFDGLLIMSPYNRRYVTEFTGTAG-------------AAIVTGGAAIF 49

Query: 75  FKQRSWIEDVVEYQKVEELM---ATVVKWIKDNGMKRVGLE-FGIERDAYLIF--YKIFL 128
                ++E   E  +  +++    T+ + I  N  K++G++  G E+ +++ F  Y++  
Sbjct: 50  ITDFRYVEQAEEQARGFDIVKHTGTIFEEIA-NQAKKLGIQKLGFEK-SHVTFETYELLN 107

Query: 129 RLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAE 188
           +L  S E+V +  L  ++R+IKDE EL+ +++A  IA          I+ G +E E+A E
Sbjct: 108 KLVDS-ELVPVAGLVENIRLIKDETELQIMQEAANIADAAFAHITSYIRAGVTEREVANE 166

Query: 189 VVRELMLNGSEDPKV-------YVSVTPRAHAEPFRDLKVPENG-IVTVVIGTDWNHYYA 240
           +   +   G+E           Y S  P   A      KV E G +VT+  G  +  Y +
Sbjct: 167 LEFFMRKQGAESSSFDIIVASGYRSALPHGVASD----KVIEKGELVTLDFGAYYKGYCS 222

Query: 241 NMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHL 300
           ++ RT  VGD  + ++K  +   EA    +E  + G+     +         +G+GEY  
Sbjct: 223 DITRTVAVGDINDELRKIYDTVLEAQLKGMEGIKPGITGKEADALTRDHITAKGYGEYFG 282

Query: 301 AGYTHGVGLLIEEPP 315
               HG+GL + E P
Sbjct: 283 HSTGHGLGLEVHEGP 297


>gb|AAG19202.1| (AE005016) probable peptidase; PepQ1 [Halobacterium sp. NRC-1]
           Length = 369
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 92/367 (25%), Positives = 153/367 (41%), Gaps = 26/367 (7%)

Query: 15  FKKRVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPS-----LLIPAEGEPTVLVVK 69
           F+ R    Q  LR+    GAV+    +  Y +G     PS     L++PA+GEP  +   
Sbjct: 4   FESRTRDCQRTLRDAGAAGAVLFPSPNLYYLSGFDET-PSERLLVLVVPADGEPAFVAPA 62

Query: 70  GEAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLR 129
                    +W++D+  Y   ++  A V     D G+    L   ++   +  F ++   
Sbjct: 63  LYETQLAAETWVDDIRTYTDSQDPSAVVRAVAADRGLTDGRLL--VDPTMWAQFTQLLRD 120

Query: 130 LNPSIEVVDILDLTM-SLRMIKDEWELENIRKAGKIALKGMR----VAEEEIKPGKSELE 184
             P      + D  + SLR+ KD+ EL+ +R+AG  A   M     +  + I  G +E E
Sbjct: 121 TLPDA-TWGLADAVLGSLRVRKDDAELDALRRAGGAADAAMADVRGLGADAI--GMTEHE 177

Query: 185 IAAEVVRELMLNGSEDPKVYV---SVTPRAHAEPFRDLKVPENGIVTVV-IGTDWNHYYA 240
           +A  +   L  +G       V   S    A      D +  + G   V   GT  + Y +
Sbjct: 178 LADFIADRLAAHGGTGVSFDVIAGSGPNGAKPHHTHDAREIQRGDPVVCDFGTVVDRYPS 237

Query: 241 NMARTFI-VGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYH 299
           +  RT +  GDP    +   EV ++A + A++    GV   AV+        + G+G+  
Sbjct: 238 DQTRTVVFAGDPPAAFRTVHEVVRDAHRAAVDAVEPGVSAGAVDAAARRVIADAGYGDAF 297

Query: 300 LAGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYENTYIVKK 358
           +    HGVGL + E P    +V     ++   MV S I P +  P E  ++ E+  +V  
Sbjct: 298 VHRTGHGVGLDVHEAP---FIVADSDRKLDVGMVFS-IEPGVYRPGEFGVRIEDLVVVTA 353

Query: 359 DKLERVT 365
           D  E +T
Sbjct: 354 DSCEPLT 360


>pir||H71496 probable aminopeptidase P - Chlamydia trachomatis (serotype D,
           strain UW3/Cx) >gi|3329016|gb|AAC68176.1| (AE001328)
           Aminopeptidase P [Chlamydia trachomatis]
           Length = 356
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 88/350 (25%), Positives = 150/350 (42%), Gaps = 31/350 (8%)

Query: 19  VERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELFKQR 78
           ++R Q+ L E  +D  +I       YF   +  R  +L+    E  + V   + +L+ + 
Sbjct: 6   IKRLQDSLVERALDAFLIEKDEDISYFLQDQ-ARSGVLLITRDEAVLFVSPLDKDLYAR- 63

Query: 79  SWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSIEVVD 138
             I+DVV     + +   +  +I++ G+K +G  F  E   Y I  K   R+N       
Sbjct: 64  --IQDVVLVSYSKSVDQELGSYIENTGLKTIG--FDSEYTPYGIAQK---RMNSGYAFSP 116

Query: 139 ILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRELMLNGS 198
              +   LR +K   E++ + +A +I   G       ++PG +E E+    VR L +  +
Sbjct: 117 QSLVAEKLRCVKSTEEIQKMTRAAEIGSAGYDFVLAALRPGITEKEL----VRMLHVFWA 172

Query: 199 EDPKVYVSVTPRA---------HAEPF-RDLKVPENGIVTVVIGTDWNHYYANMARTFIV 248
                 VS  P           HA P  R LK  +  +V + IG  +  Y ++M RT   
Sbjct: 173 NLGIEKVSFPPIIAFGENAAFPHAIPTNRSLK--KGDVVLIDIGVCYEGYCSDMTRTVAF 230

Query: 249 G-DPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGV 307
           G  P +++        EA + A+E  R GVP   V K+     +  G  +  + G  HGV
Sbjct: 231 GATPEQQLLDGYVAVAEAQRAAIEFCRAGVPCRDVHKEAVRILRAHGMEKAFIHGLGHGV 290

Query: 308 GLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYENTYIV 356
           G  + E P  +   P     +Q NM ++ + P +  P  G I+ E+T ++
Sbjct: 291 GREVHEYPRLS---PFSDATLQLNMAVT-VEPGVYFPGVGGIRIEDTIMI 336


>emb|CAB93372.1| (AL357523) putative peptidase [Streptomyces coelicolor A3(2)]
           Length = 368
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 59/234 (25%), Positives = 110/234 (46%), Gaps = 10/234 (4%)

Query: 132 PSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVR 191
           P++ + D+      LR++KDE E+  +R   +IA + +    E I  G++E  +A E+ R
Sbjct: 121 PALRLTDLGQAVEQLRVVKDEEEISCLRIGAEIADQALGELLESILVGRTERHLALELER 180

Query: 192 ELMLNGSEDPKVYVSVT--PRAHAEPFR--DLKVPENGIVTVVIGTDWNHYYANMARTFI 247
            L+ +G++ P    SV   P +     R  D +V E   ++V +G  +  Y   + RTF+
Sbjct: 181 RLVDHGADGPAFPTSVGTGPNSGRRGHRPTDRRVEEGDFLSVCLGATYRGYRCEIGRTFV 240

Query: 248 VG-DPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHG 306
           +G  P +   +  ++   A +   E    G     V++         G+ E+  A   HG
Sbjct: 241 IGTSPADWQIELYDLVFSAQRAGREALAPGAACRDVDRAARQPLDSAGYAEHLPALTGHG 300

Query: 307 VGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYENTYIVKKD 359
           VGL I+E P    + P    ++ +  V   + P + LP  G ++ ++T +V+ +
Sbjct: 301 VGLEIDEDP---QLAPAAMGKL-DACVPVTVEPGVHLPGRGGVRIDDTLVVRPE 350


>gb|AAK40375.1| X-pro aminopeptidase [Sulfolobus solfataricus]
           Length = 351
           
 Score = 73.7 bits (178), Expect = 3e-12
 Identities = 87/351 (24%), Positives = 151/351 (42%), Gaps = 28/351 (7%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTG---TKWLRPSLLIPAEGEPTVLVVKGEAEL 74
           R++R Q+ L   N D  +  T S+  Y  G    +  RP LL     +  +LV K   E 
Sbjct: 3   RIQRVQKELERANADYLITGTTSNMYYLIGFSEEQMERPLLLFITRDDYFLLVPKLYEEQ 62

Query: 75  FKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSI 134
            KQ      ++ Y+  E+  + +   +K+N    +      +    L   +I  R  P  
Sbjct: 63  LKQFP----LIVYRDGEDPYSKLN--LKENSNVLID-----DTTFSLFTIEILNRFKPG- 110

Query: 135 EVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRELM 194
            +     +   LR +KD+ ELE + K  K A + +      IK   +E +I  ++   L+
Sbjct: 111 RIGRASRILGKLRQVKDDEELEKMEKGVKKAEQLILEFVSNIKENMTECQIERKLKSFLI 170

Query: 195 L---NGSEDPKVYVSVTPRAHAEPFR--DLKVPENGIVTVVIGTDWNHYYANMARTFIVG 249
               N S DP   V+  P +     R  D KV     + +  G   + Y  +  R F +G
Sbjct: 171 EEAGNISFDP--IVTSGPNSSMPHLRCSDKKVKRGEAIVIDYGIKHDGYSTDTTRVFSLG 228

Query: 250 DPGER-VKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVG 308
            P +  + + +E+ K A + A +  R G+    ++         +G+G+Y +    HG+G
Sbjct: 229 KPNDPLILEIVEIVKTANEEAEKHVREGMRAKEIDYFAREVITNKGYGDYFIHRTGHGIG 288

Query: 309 LLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYENTYIVKK 358
           + + E P    + P     I++NMV + I P + LP +  I+ E+  +VKK
Sbjct: 289 IDVHEDP---YISPDNDDVIEQNMVFT-IEPGIYLPGKFGIRIEDEVVVKK 335


>gb|AAC46293.1| (AF014460) PepQ [Streptococcus mutans]
           Length = 359
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 82/366 (22%), Positives = 154/366 (41%), Gaps = 36/366 (9%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTG---TKWLRPSLLIPAEGEPTVLVVKGEAEL 74
           ++ +  + L++  I+ AV+    S  Y TG       R   L     + T+L +  E + 
Sbjct: 3   KLAQIVQKLKKQGIEAAVLSDPVSINYLTGFYSDPHERLMFLFLFADQETLLFLP-ELDA 61

Query: 75  FKQRSWIE-DVVEYQKVEELMATVVKWIKDNGMKRVGLEF---------GIERDAYLIFY 124
            + +S ++  V  Y   E  +  +   +      ++ LEF         G+E     IF 
Sbjct: 62  LRAKSILDISVTGYLDFENPLEKIKTLLPKTNYSKIALEFDNLNVTKFKGLET----IFS 117

Query: 125 KIFLRLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELE 184
             F  L P I           +R+IK   E++ +  AG++A K +++  + I    +E +
Sbjct: 118 GQFTNLTPLIN---------RMRLIKSADEIQKLLIAGELADKAVQIGFDSISLNATETD 168

Query: 185 IAAEVVRELMLNGSEDPKVYVSVTPRAHAEPFRDL----KVPENGIVTVVIGTDWNHYYA 240
           I A++  E+   G +       V   ++A     L    K+  N ++   +G +   Y +
Sbjct: 169 IIAQIEFEMKKLGVDKMSFETMVLTGSNAANPHGLPASHKIENNHLLLFDLGVESTGYVS 228

Query: 241 NMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHL 300
           +M RT  VG P +  K    +  EA   AL+  + GV  + V+       ++ G+G+Y  
Sbjct: 229 DMTRTVAVGQPDQFKKDIYNICLEAQLTALDFIKPGVSAAQVDAAARSVIEKAGYGDYFN 288

Query: 301 AGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEG-AIKYENTYIVKKD 359
               HG+G+ + E P    ++      ++E M  S + P + +PE   ++ E+   V K+
Sbjct: 289 HRLGHGIGMGLHEFP---SIMAGNDMLLEEGMCFS-VEPGIYIPEKVGVRIEDCGHVTKN 344

Query: 360 KLERVT 365
             E  T
Sbjct: 345 GFEVFT 350


>pir||B72032 proline dipeptidase CP1058 [imported] - Chlamydophila pneumoniae
           (strains CWL029 and AR39) >gi|4377125|gb|AAD18951.1|
           (AE001662) Aminopeptidase P [Chlamydophila pneumoniae
           CWL029] >gi|7189972|gb|AAF38831.1| (AE002263) proline
           dipeptidase [Chlamydophila pneumoniae AR39]
           >gi|8979187|dbj|BAA99021.1| (AP002548) aminopeptidase P
           [Chlamydophila pneumoniae J138]
           Length = 355
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 77/349 (22%), Positives = 150/349 (42%), Gaps = 20/349 (5%)

Query: 18  RVERFQELLRENNIDGAVIRTLSSFIYFTGTKWLRPSLLIPAEGEPTVLVVKGEAELFKQ 77
           R+ R Q  L E+N+D  ++       YF   + +   LLI  + E    V + + +L+  
Sbjct: 5   RILRAQRALSEHNLDAILVEKSEDLAYFLHDEAIAGILLI-GQQEVMFFVYRMDKDLY-- 61

Query: 78  RSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIFLRLNPSIEVV 137
            S I+ V      ++++A +  +++    +++G +      A  +++K   R        
Sbjct: 62  -SHIQRVPLTFLTQDVVADLSLYVQKQRYQKIGFD-----SASTVYHKFAQRQVLPCLWE 115

Query: 138 DILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAEVVRELMLNG 197
            +   T  +R IK E E+  +++A  +   G       ++ G +E E+  ++       G
Sbjct: 116 PLECFTEKIRSIKSEEEIRRMQEAAALGSAGYDYVLTLLREGITEKEVVRQLRAFWAEAG 175

Query: 198 SEDPK-----VYVSVTPRAHAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTFIVGDPG 252
           +E P       +   +   H+ P  D  + +  IV + IG   N Y ++M R   +G P 
Sbjct: 176 AEGPSFPPIIAFGEHSAFPHSIP-TDRPLKKGDIVLIDIGVLLNGYCSDMTRMTALGTPH 234

Query: 253 ERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYTHGVGLLIE 312
            ++ ++  V  EA K A+   + GV    ++ +     +E     Y + G  HGVG  I 
Sbjct: 235 PKLLESYPVVVEAQKRAMALCKEGVLWGDIDAEAVRVLREHHLDTYFIHGIGHGVGRHIH 294

Query: 313 EPPIATIVVPQRATRIQENMVLSIIHPPLMLPE-GAIKYENTYIVKKDK 360
           E P +    P+ +    E+ +   + P +  P  G I+ E+T  + K+K
Sbjct: 295 EYPCS----PRGSQVKLESGMTITVEPGVYFPGIGGIRIEDTLCIDKNK 339


>pir||D75419 proline dipeptidase - Deinococcus radiodurans (strain R1)
           >gi|6458990|gb|AAF10817.1|AE001972_7 (AE001972) proline
           dipeptidase [Deinococcus radiodurans]
           Length = 349
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 71/261 (27%), Positives = 113/261 (43%), Gaps = 15/261 (5%)

Query: 110 GLEFGIERDAYLIFYKIFLRLN-PSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKG 168
           GL  G E ++  +     LR   P+  +V +      LR +K   E+  IR A  +A + 
Sbjct: 86  GLRVGFEAESLTVAELEDLRQAWPNSTLVALRGTLGGLRAVKTPEEIGAIRAAQDLADRV 145

Query: 169 MRVAEEEIKPGKSELEIAAEVVRELMLNGSEDPKVYVSVTPRAHAEPF--RDLKVPENG- 225
                  I+ G  EL++A E+   L   G E     +  +    A+P      +V E+G 
Sbjct: 146 YTEVRPMIRAGVRELDVAVEIETRLRRAGGESAFELIVASGPNGAKPHGHASKRVIEDGD 205

Query: 226 IVTVVIGTDWNHYYANMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKK 285
           +VT+ +G     Y ++M RT  VG P   +K+  +   EA + A+   R GV  + ++K 
Sbjct: 206 LVTIDMGARLGGYNSDMTRTVAVGTPSAEMKRVYDAVLEAEEAAIAAIRPGVRAADLDKL 265

Query: 286 IEHFFKERGFGEYHLAGYTHGVGLLIEEPPIATIVVPQRATR---IQENMVLSIIHPPLM 342
                   G GE       HGVGL + E P        R T    ++  MV++ I P   
Sbjct: 266 ARDLLTRHGLGEAFAHSLGHGVGLEVHEGP------GLRGTSQDVLEAGMVIT-IEPGAY 318

Query: 343 LP-EGAIKYENTYIVKKDKLE 362
           LP  G ++ E+  +V +D  E
Sbjct: 319 LPGVGGVRIEDLILVTEDGYE 339


>pir||F72247 methionine aminopeptidase - Thermotoga maritima (strain MSB8)
           >gi|4982042|gb|AAD36544.1|AE001798_9 (AE001798)
           methionine aminopeptidase [Thermotoga maritima]
           Length = 250
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 65/229 (28%), Positives = 106/229 (45%), Gaps = 21/229 (9%)

Query: 149 IKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAA---EVVRELMLN------GSE 199
           IK   E+E ++KAGK     +R   + I PGK+  ++     E+ ++L +       G  
Sbjct: 4   IKTPSEIEKMKKAGKAVAVALREVRKVIVPGKTAWDVETLVLEIFKKLRVKPAFKGYGGY 63

Query: 200 DPKVYVSVTPRA-HAEPFRDLKVPENGIVTVVIGTDWNHYYANMARTFIVGDPGERVKKA 258
                VSV     H  P ++    E  IV+V +G  +   Y + A T+IVG+  ER K+ 
Sbjct: 64  KYATCVSVNEEVVHGLPLKEKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVGETDERGKEL 123

Query: 259 IEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHLAGYT-HGVGL-LIEEPPI 316
           + V +E L+ A++  + G+ +  V   I+   +  GF    +  Y  HGVG  L E+P I
Sbjct: 124 VRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNV--IRDYVGHGVGRELHEDPQI 181

Query: 317 ATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYENTYIVKKDKLERVT 365
                P     +++ M L+I     M+ EG    +   +VK+D    VT
Sbjct: 182 PNYGTPGTGVVLRKGMTLAI---EPMVSEG----DWRVVVKEDGWTAVT 223


>pir||T47008 hypothetical protein [imported] - Yersinia pestis
           >gi|4106596|emb|CAA21351.1| (AL031866) ORF28, len: 405
           aa, similar to a  proline peptidase protein in Bacillus
           subtilis O31689, Fasta scores  opt: 354, E(): 2.6e-15,
           25.7% identity in 284 aa overlap, and Streptococcus
           lactis O08316, Fasta scores:  opt:  332, E(): 6.3e-14,
           25.9% i>
           Length = 405
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 60/250 (24%), Positives = 105/250 (42%), Gaps = 30/250 (12%)

Query: 129 RLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGKSELEIAAE 188
           ++ P +++VD   L   +RMIK  WE+E++RK+ +I   G+  A ++I+ G +  E+ A 
Sbjct: 157 KVAPGLKLVDSTALFNEIRMIKSPWEIEHLRKSAEITEYGIASAAKKIRVGCTAAELTAA 216

Query: 189 VVRELM--------------LNGSEDPKVYVSVTPRAHAEPFRDLKVPENGIVTVVIGTD 234
               +M              +  +  PK+    TP    +           ++    G D
Sbjct: 217 FKAAVMSFPETNFSRFNLISVGDNFSPKIIADTTPAKVGD-----------LIKFDCGID 265

Query: 235 WNHYYANMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERG 294
              Y A++ARTF++G+P +  ++  +  +   +  L     GV + AV        K  G
Sbjct: 266 VAGYGADLARTFVLGEPDKLTQQIYDTIRTGHEHMLSMVAPGVKLKAVFDSTMAVIKTSG 325

Query: 295 FGEYHLAGYTHGVGLL--IEEPPIATIVVPQRATRIQENMVLSIIHPPLMLPEGAIKYEN 352
              Y+     HG G+   +EE P    V  Q        MVLS+  P   +  G+I  E+
Sbjct: 326 LPHYNRGHLGHGDGVFLGLEEVP---FVSTQATETFCPGMVLSLETPYYGIGVGSIMLED 382

Query: 353 TYIVKKDKLE 362
             ++     E
Sbjct: 383 MILITDSGFE 392


>sp|P55666|Y4TL_RHISN HYPOTHETICAL HYDROLASE/PEPTIDASE Y4TL >gi|2182642|gb|AAB91865.1|
           (AE000098) Y4tL [Rhizobium sp. NGR234]
           Length = 390
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 74/317 (23%), Positives = 144/317 (45%), Gaps = 28/317 (8%)

Query: 15  FKKRVERFQELLRENNIDGAVIRTLSSFIYFTG----TKWLRPSLLIPA-EGEPTVLVVK 69
           F +R+   +  +    ID  ++ + +   Y TG    + ++  +L+I + + EPT ++ +
Sbjct: 15  FLRRLNAVKLEMGRLEIDALIVGSSADITYLTGYTAKSGYVPQALVISSNDEEPTFILRR 74

Query: 70  GEAELFKQRSWIE--DVVEYQKV------EELMATVVKWI--KDNGMKR-VGLEFGIERD 118
            +A     +++++   V+ Y +       ++    VV ++  +D   KR VG++ G    
Sbjct: 75  QDAPAAIHQTFMDRDKVIGYSEALIGNPDKDGYDAVVDFLNERDGANKRGVGVQLGYLSV 134

Query: 119 AYLIFYKIFLRLNPSIEVVDILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKP 178
                +K  L   PS  +VD       +RMIK + E+  +R A  IA  G++ A E I+P
Sbjct: 135 RSAEKFKTRL---PSARIVDCTHSVAWIRMIKSDLEISMMRDAAAIADAGVQKAFEVIRP 191

Query: 179 GKSELEIAAEVVRELMLN-----GSEDPKVYVSVTPR---AHAEPFRDLKVPENGIVTVV 230
           G  E ++ A+V  +L        G++   +Y   +PR    H     D+ + +   + + 
Sbjct: 192 GVREADVMADVAAQLARGTNGKAGTDLASMYFCSSPRTGTCHIRWSEDV-IRDGSQINLE 250

Query: 231 IGTDWNHYYANMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFF 290
           I    + Y + + RTF VG P +R+++  + +   L+ AL   + G   S V        
Sbjct: 251 IAGVRHGYVSAIMRTFSVGAPSDRLRRIHDAEVLGLEAALSTVKPGATCSDVANAFYRTI 310

Query: 291 KERGFGEYHLAGYTHGV 307
           ++ GF +    GY  G+
Sbjct: 311 EKSGFQKDSRCGYAIGI 327


>emb|CAB07979.1| (Z93945) prolidase-related protein [Lactobacillus delbrueckii]
           Length = 373
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 84/353 (23%), Positives = 142/353 (39%), Gaps = 19/353 (5%)

Query: 12  KEIFKKRVERFQELLRENNIDGAVIRTLSSFIYFTG-TKWLRP---SLLIPAEGEPTVLV 67
           K  +++ +      L E  ID A +       Y TG + W      +LL+   G+  +L 
Sbjct: 6   KLTWEEHLAALTSYLDEKGIDLAYVAEPVDIAYLTGYSSWTEERVFALLVSRTGQALLLA 65

Query: 68  VKGEAELFKQRSWIEDVVEYQKVEELMATVVKWIKDNGMKRVGLEFGIERDAYLIFYKIF 127
                   KQ SW +    YQ  E       K +         LE    R   L  Y+  
Sbjct: 66  PAINEGEVKQTSWADRACFYQDGENPWEKAKKRMTAWPKGFWALE---ARAVTLSHYRAI 122

Query: 128 LRLNPSIEVV-DILDLTMSLRMIKDEWELENIRKAGKIALKGMRVAEEEIKPGK--SELE 184
             + P   +  DI       RMIK   E+E ++ AG++A + + +A   +K G+  SE E
Sbjct: 123 KEVFPEANLASDISTWLARQRMIKSPAEIEKLQAAGRLADQALDLAFALLKAGQGMSESE 182

Query: 185 IAAEVVRELMLNGSEDPKVYVSVTPRAHAEPFRDLK----VPENGIVTVVIGTDWNHYYA 240
           +A E+  +L   G  D    + V     A     L     V    IV   +G   + Y +
Sbjct: 183 LALELDYQLKKKGMGDLSFPLIVQAGESAASISGLPSQKGVQAGDIVIFDLGIMKDGYAS 242

Query: 241 NMARTFIVGDPGERVKKAIEVKKEALKLALEETRVGVPISAVEKKIEHFFKERGFGEYHL 300
           +++RT  +G+      +  E  + A + A    R G+    +++      +E G+G+Y  
Sbjct: 243 DVSRTVALGEISPAKWEIYETVRLAQETAARAARPGMTAGELDQVARGVIEEAGYGQYFT 302

Query: 301 AGYTHGVGLLIEEPPIATIVVPQRATRIQENMVLSIIHPPLMLP-EGAIKYEN 352
               HG+G+ + EP     + P    +++  M  S I P + LP  G ++ E+
Sbjct: 303 HRLGHGIGMQVHEP---VNLEPGSKQKLEAGMCFS-IEPGIYLPGVGGVRIED 351


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.139    0.394 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 135800371
Number of Sequences: 2977
Number of extensions: 5685391
Number of successful extensions: 14940
Number of sequences better than 1.0e-10: 36
Number of HSP's better than  0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 14870
Number of HSP's gapped (non-prelim): 37
length of query: 365
length of database: 189,106,746
effective HSP length: 57
effective length of query: 308
effective length of database: 154,992,987
effective search space: 47737839996
effective search space used: 47737839996
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)