BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2195 (htrA-like) DE:SERINE PROTEASE HTRA related protein
(378 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75213 serine proteinase htra related protein PAB2195 - Pyr... 751 0.0
pir||A71450 hypothetical protein PH0256 - Pyrococcus horikoshii ... 600 e-170
pir||H69048 conserved hypothetical protein MTH1368 - Methanobact... 203 2e-51
pir||S75400 hypothetical protein c04034 - Sulfolobus solfataricu... 157 3e-37
gb|AAK40447.1| Conserved hypothetical protein [Sulfolobus solfat... 157 3e-37
pir||G72777 probable S2P metalloproteinase APE0209 - Aeropyrum p... 138 1e-31
sp|Q58381|Y971_METJA HYPOTHETICAL PROTEIN MJ0971 >gi|2128608|pir... 134 1e-30
gi|11498920 conserved hypothetical protein [Archaeoglobus fulgid... 130 2e-29
emb|CAC12398.1| (AL445067) sterol-regulatory element-binding pro... 98 2e-19
gb|AAG20184.1| (AE005095) Vng2019c [Halobacterium sp. NRC-1] 95 2e-18
pir||T05339 hypothetical protein F1C12.220 - Arabidopsis thalian... 88 2e-16
sp|O54862|MS2P_CRIGR STEROL-REGULATORY ELEMENT-BINDING PROTEINS ... 81 2e-14
gi|7706693 S2P protein [Homo sapiens] >gi|6016601|sp|O43462|MS2P... 80 6e-14
gi|11419639 S2P protein [Homo sapiens] 80 6e-14
gb|AAF58617.1| (AE003824) CG8988 gene product [Drosophila melano... 78 1e-13
emb|CAB60513.1| (AL132860) predicted using Genefinder~contains s... 71 3e-11
>pir||H75213 serine proteinase htra related protein PAB2195 - Pyrococcus abyssi
(strain Orsay) >gi|5457668|emb|CAB49159.1| (AJ248283)
SERINE PROTEASE HTRA related protein [Pyrococcus abyssi]
Length = 378
Score = 751 bits (1917), Expect = 0.0
Identities = 378/378 (100%), Positives = 378/378 (100%)
Query: 1 MSVLGTLTNVILGILGFWAVIGILGVTVLKDSKSLEIAPFQIIWRTKRFLDFIDRVGREH 60
MSVLGTLTNVILGILGFWAVIGILGVTVLKDSKSLEIAPFQIIWRTKRFLDFIDRVGREH
Sbjct: 1 MSVLGTLTNVILGILGFWAVIGILGVTVLKDSKSLEIAPFQIIWRTKRFLDFIDRVGREH 60
Query: 61 KGFWRIYGDIGIIAGFGGMAFVLYYFLKQAYNILRPTAEVVPSVQLVIPGVTIPLVYGLI 120
KGFWRIYGDIGIIAGFGGMAFVLYYFLKQAYNILRPTAEVVPSVQLVIPGVTIPLVYGLI
Sbjct: 61 KGFWRIYGDIGIIAGFGGMAFVLYYFLKQAYNILRPTAEVVPSVQLVIPGVTIPLVYGLI 120
Query: 121 SLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFA 180
SLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFA
Sbjct: 121 SLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFA 180
Query: 181 AGSFANFIVAFISVLVFNGVTLAFEPHGVEVFGVIKDSPAYGILEKGDVIVEINGVKINT 240
AGSFANFIVAFISVLVFNGVTLAFEPHGVEVFGVIKDSPAYGILEKGDVIVEINGVKINT
Sbjct: 181 AGSFANFIVAFISVLVFNGVTLAFEPHGVEVFGVIKDSPAYGILEKGDVIVEINGVKINT 240
Query: 241 LEEFIKFMNNTKPGEELSLVILRNGKVKNISITLGEHPERPGKGFIGIYPTQHLISKIGF 300
LEEFIKFMNNTKPGEELSLVILRNGKVKNISITLGEHPERPGKGFIGIYPTQHLISKIGF
Sbjct: 241 LEEFIKFMNNTKPGEELSLVILRNGKVKNISITLGEHPERPGKGFIGIYPTQHLISKIGF 300
Query: 301 DKELMVIFTLFYWLYVINFGVGLMNLLPVIPLDGGRMLIDTLTELSPRFGKIVGYSIMVL 360
DKELMVIFTLFYWLYVINFGVGLMNLLPVIPLDGGRMLIDTLTELSPRFGKIVGYSIMVL
Sbjct: 301 DKELMVIFTLFYWLYVINFGVGLMNLLPVIPLDGGRMLIDTLTELSPRFGKIVGYSIMVL 360
Query: 361 SLILLGINLLPTIRGFVG 378
SLILLGINLLPTIRGFVG
Sbjct: 361 SLILLGINLLPTIRGFVG 378
>pir||A71450 hypothetical protein PH0256 - Pyrococcus horikoshii
>gi|3256645|dbj|BAA29328.1| (AP000001) 377aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 377
Score = 600 bits (1530), Expect = e-170
Identities = 287/379 (75%), Positives = 338/379 (88%), Gaps = 3/379 (0%)
Query: 1 MSVLGTLTNVILGILGFWAVIGILGVTVLKDSKSLEIAPFQIIWRTKRFLDFIDRVGREH 60
M +LGTLT ILGIL FWA+I ILG ++ S+SLEIAPFQIIWRTK+F++FIDR+GR++
Sbjct: 1 MGLLGTLTYAILGILIFWALISILGTSMR--SESLEIAPFQIIWRTKKFINFIDRIGRKY 58
Query: 61 KGFWRIYGDIGIIAGFGGMAFVLYYFLKQAYNILRPTAEV-VPSVQLVIPGVTIPLVYGL 119
+ FW+IYGD+GII GFGGM FVLYYF KQAYNI+RP V +PSVQLVIPGVTIPLVYGL
Sbjct: 59 QRFWKIYGDLGIITGFGGMIFVLYYFAKQAYNIIRPIKPVTMPSVQLVIPGVTIPLVYGL 118
Query: 120 ISLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVF 179
I+LA+L+IVHELSHGFVAR+E+IPLKSVGLL FI++PGAFVEPDED+LKKAPLRSRLRVF
Sbjct: 119 IALAILVIVHELSHGFVARSEDIPLKSVGLLLFIIIPGAFVEPDEDQLKKAPLRSRLRVF 178
Query: 180 AAGSFANFIVAFISVLVFNGVTLAFEPHGVEVFGVIKDSPAYGILEKGDVIVEINGVKIN 239
AGSFANF+VA IS+L+ NG+ LAFEPHGVE+ G IKDSPAY +L+KGDVI+ ING+KI
Sbjct: 179 GAGSFANFVVALISLLLVNGIALAFEPHGVEIAGTIKDSPAYNVLQKGDVIIGINGMKIE 238
Query: 240 TLEEFIKFMNNTKPGEELSLVILRNGKVKNISITLGEHPERPGKGFIGIYPTQHLISKIG 299
TLEEF++FMN T+P EE++L ++RN K+ NISI LGEHPER GKGFIGIYPTQH ISKIG
Sbjct: 239 TLEEFMEFMNKTRPNEEITLTVIRNKKIINISIILGEHPERAGKGFIGIYPTQHWISKIG 298
Query: 300 FDKELMVIFTLFYWLYVINFGVGLMNLLPVIPLDGGRMLIDTLTELSPRFGKIVGYSIMV 359
FDK L ++ T FYW+YV+NFGVGLMNLLPVIPLDGGRMLIDTLTELSP+FGK +GYSIM+
Sbjct: 299 FDKPLTIVLTTFYWIYVLNFGVGLMNLLPVIPLDGGRMLIDTLTELSPKFGKAIGYSIML 358
Query: 360 LSLILLGINLLPTIRGFVG 378
+SL+LLGINL+P IRGFVG
Sbjct: 359 ISLLLLGINLIPAIRGFVG 377
>pir||H69048 conserved hypothetical protein MTH1368 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622476|gb|AAB85845.1| (AE000899) conserved protein
[Methanobacterium thermoautotrophicum]
Length = 389
Score = 203 bits (512), Expect = 2e-51
Identities = 132/387 (34%), Positives = 202/387 (52%), Gaps = 34/387 (8%)
Query: 12 LGILGFWAVIGILGVTV---LKDSKSLEIAPFQIIWRTKRFLDFIDRVGREHKGFWRIYG 68
+ L F+ + IL T+ +D +EI ++ RTKR FID + H WR
Sbjct: 5 MNALWFYLIAFILIWTMAILFRDRLKIEIHGPLLMRRTKRLRGFIDGLASGHPKLWRWIM 64
Query: 69 DIGIIAGFGGMAFVLYYFLKQAYNILRPTAEVVPSVQLVIPGVTIP-------LVYGLIS 121
+ GI F M ++LY + NI V P L++PGV IP L YG+I
Sbjct: 65 NAGIPVAFFFMFYMLYMLVMSLQNIF-----VTPQASLIVPGVDIPGSPVYVPLGYGIIG 119
Query: 122 LAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFAA 181
LA +I+VHE +HG +AR E + +KS+GLL +LPGAFVEPDE+++KK S++R++AA
Sbjct: 120 LATVIVVHEFAHGILARLEGVRIKSIGLLLLAILPGAFVEPDEEDIKKIRPISKMRIYAA 179
Query: 182 GSFANFIVAFISVLVFNGVT-----LAFEPHGVEVFGVIKDSPAYGILEKGDVIVEINGV 236
GS AN I+A I +F G++ AF+P GV++ V+ SPA +L G VI ING+
Sbjct: 180 GSVANLILAGICFALFFGISSFAMPAAFQPDGVQIDSVVPGSPASKVLTPGLVIESINGM 239
Query: 237 KINTLEEFIKFMNNTKPGEELSLVILRNGKVKNISITLGEHPERPGKGFIGIYPTQHL-- 294
+ L + + GE +++ + + G +P + ++GI + HL
Sbjct: 240 PTSNLTTYSAALKTISVGEVINITTDQG----TFHLKTGRNPNNSSRAYMGIRTSNHLRV 295
Query: 295 ----ISKIG--FDKELMVIFTLFYWLYVINFGVGLMNLLPVIPLDGGRMLIDTLTELSPR 348
S +G L + LF+W++ +NF VG +NLLP PLDGG M + L P
Sbjct: 296 RDSVASVLGDTLPFALTYLEELFFWIFFLNFAVGTVNLLPAKPLDGGLMFEELLRYRLPE 355
Query: 349 FGKIVGYSIMVLSLILLGINLLPTIRG 375
+IV ++ +S+ ++ I + I G
Sbjct: 356 --RIVKPAVSYVSIFVILIIAVSIIWG 380
>pir||S75400 hypothetical protein c04034 - Sulfolobus solfataricus
>gi|1707806|emb|CAA69563.1| (Y08257) orf c04034
[Sulfolobus solfataricus]
Length = 386
Score = 157 bits (392), Expect = 3e-37
Identities = 103/366 (28%), Positives = 186/366 (50%), Gaps = 42/366 (11%)
Query: 15 LGFWAVIGILGVTVLKDSKSLEIAPFQIIWRTKRFLDFIDRVGRE--HKGFWRIYGDIGI 72
L FW +I + + K +L + PF I+WR K + + R ++ + +I IG
Sbjct: 34 LSFWLIIYVFRRRLEK--YNLTVYPFFILWRKKSREYWFPKFSRSKGYRAYEKIALPIGF 91
Query: 73 IAGFGGMAFVLYYFLKQAYNILRPTAEVVPSVQLVIPGVTIP---LVYGLISLAVLIIVH 129
+ G+ +LY ++ ++P +++ +IPGVTI L Y L+++ V + +H
Sbjct: 92 LLMIAGIVTILYIIIEML--TIKPNQTPTIALKPIIPGVTISISQLPYILLAIGVSVAIH 149
Query: 130 ELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFAAGSFANFIV 189
E+ H A + N+ +K+ G+L + PGAFVEPDED+ K+ ++L++ AAG N ++
Sbjct: 150 EIFHALSATSNNVKVKNGGVLLLGIFPGAFVEPDEDDFNKSTSNAKLKIIAAGIVINLVL 209
Query: 190 AFISVLVFNGVTLAFE--------PHGVEVFGVIKDSPAYGI-LEKGDVIVEINGVKINT 240
A I+ + L+FE G+ + GV+ ++PA L GD+I ING ++ T
Sbjct: 210 ALIA------LPLSFELPYLPSALSQGIIIEGVLNNTPAANASLHTGDIIYSINGYRLTT 263
Query: 241 LEEFIKFMNNTKPGEELSLVILR-NGKVKNISITLGEHPERPGKGFIGIYPTQHLISKIG 299
L + + + N +++ + NG + N+S+ + H F+G+Y T ++ I
Sbjct: 264 LSQLHELLYNY---STITITLKHPNGSLSNVSVNIPNH-------FLGVYVTYYIPDYIA 313
Query: 300 FDKELMVIFTLFYWLYVINFGVGLMNLLPVIPLDGGRMLIDTLTE-LSPRFGKIVGYSIM 358
I F WL+++NF + + N P+I DGG++L + L L G+ + Y +
Sbjct: 314 ------AILMFFTWLFIVNFSLAVFNAAPLIITDGGKLLTELLKRMLGESNGEKISYYLQ 367
Query: 359 VLSLIL 364
L L++
Sbjct: 368 SLFLLI 373
>gb|AAK40447.1| Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 386
Score = 157 bits (392), Expect = 3e-37
Identities = 103/366 (28%), Positives = 186/366 (50%), Gaps = 42/366 (11%)
Query: 15 LGFWAVIGILGVTVLKDSKSLEIAPFQIIWRTKRFLDFIDRVGRE--HKGFWRIYGDIGI 72
L FW +I + + K +L + PF I+WR K + + R ++ + +I IG
Sbjct: 34 LSFWLIIYVFRRRLEK--YNLTVYPFFILWRKKSREYWFPKFSRSKGYRAYEKIALPIGF 91
Query: 73 IAGFGGMAFVLYYFLKQAYNILRPTAEVVPSVQLVIPGVTIP---LVYGLISLAVLIIVH 129
+ G+ +LY ++ ++P +++ +IPGVTI L Y L+++ V + +H
Sbjct: 92 LLMIAGIVTILYIIIEML--TIKPNQTPTIALKPIIPGVTISISQLPYILLAIGVSVAIH 149
Query: 130 ELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFAAGSFANFIV 189
E+ H A + N+ +K+ G+L + PGAFVEPDED+ K+ ++L++ AAG N ++
Sbjct: 150 EIFHALSATSNNVKVKNGGVLLLGIFPGAFVEPDEDDFNKSTSNAKLKIIAAGIVINLVL 209
Query: 190 AFISVLVFNGVTLAFE--------PHGVEVFGVIKDSPAYGI-LEKGDVIVEINGVKINT 240
A I+ + L+FE G+ + GV+ ++PA L GD+I ING ++ T
Sbjct: 210 ALIA------LPLSFELPYLPSALSQGIIIEGVLNNTPAANASLHTGDIIYSINGYRLTT 263
Query: 241 LEEFIKFMNNTKPGEELSLVILR-NGKVKNISITLGEHPERPGKGFIGIYPTQHLISKIG 299
L + + + N +++ + NG + N+S+ + H F+G+Y T ++ I
Sbjct: 264 LSQLHELLYNY---STITITLKHPNGSLSNVSVNIPNH-------FLGVYVTYYIPDYIA 313
Query: 300 FDKELMVIFTLFYWLYVINFGVGLMNLLPVIPLDGGRMLIDTLTE-LSPRFGKIVGYSIM 358
I F WL+++NF + + N P+I DGG++L + L L G+ + Y +
Sbjct: 314 ------AILMFFTWLFIVNFSLAVFNAAPLIITDGGKLLTELLKRMLGESNGEKISYYLQ 367
Query: 359 VLSLIL 364
L L++
Sbjct: 368 SLFLLI 373
>pir||G72777 probable S2P metalloproteinase APE0209 - Aeropyrum pernix (strain
K1) >gi|5103600|dbj|BAA79121.1| (AP000058) 383aa long
hypothetical S2P metalloprotease [Aeropyrum pernix]
Length = 383
Score = 138 bits (344), Expect = 1e-31
Identities = 104/327 (31%), Positives = 165/327 (49%), Gaps = 37/327 (11%)
Query: 61 KGFWRIYGDIGIIAGFGGMAFVLYYFLKQAY-NILRPTAE---VVPSVQLVIPGVTIP-- 114
+G R+YG + I +A Y L+ A L P E +IPGVTIP
Sbjct: 59 RGVLRLYGYLAIAVMMAALALFYYLALQAAKAKFLVPPGEGGEAAGGFIPLIPGVTIPWE 118
Query: 115 -LVYGLISLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLR 173
LVY ++L V ++ HEL H VA AE I +K+ G+ + +P AFVE DE++L KA L
Sbjct: 119 DLVYVAVALGVGVVAHELGHAVVAVAEGIRVKNAGIAILLFIPAAFVELDEEQLMKARLV 178
Query: 174 SRLRVFAAGSFANFIVAFISVLVFNGVTLAFEPHGVEVFGVIKDSPAYGI-LEKGDVIVE 232
SRL+VF+AG AN ++A +++L+ +A EP GV++ GV + SPA L G VIVE
Sbjct: 179 SRLKVFSAGVTANILIALLTLLIAMTAPVA-EPSGVKILGVEEGSPADAAGLGPGMVIVE 237
Query: 233 INGVKINTLEEFIKFMNN---TKPGEELSLVI---LRNGKVKNISITLGEHPERPGKGFI 286
+NG + +LE+ + T P + + G++ ++ + + G+ I
Sbjct: 238 VNGEPVKSLEDLRRIFEKIGVTDPASNVEFTVRVKKEGGELLDLKVV-----KEAGRSTI 292
Query: 287 GIYPTQHLISKIGFDKELMVIFTLFYWLYVINFGVGLMNLLP-VIPL-------DGGRML 338
G+ + S + T+ L+++N GV L+N P ++PL DGG +
Sbjct: 293 GVRVAEFYDSPLA---------TIMNALFLLNLGVALVNAAPLLLPLPGAAIMSDGGHVA 343
Query: 339 IDTLTELSPRFGKIVGYSIMVLSLILL 365
+ L G+++G + V +LIL+
Sbjct: 344 VHVGERLLGPSGRLLGAGLGVATLILV 370
>sp|Q58381|Y971_METJA HYPOTHETICAL PROTEIN MJ0971 >gi|2128608|pir||C64421 hypothetical
protein MJ0971 - Methanococcus jannaschii
>gi|1591634|gb|AAB98976.1| (U67540) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 365
Score = 134 bits (335), Expect = 1e-30
Identities = 106/302 (35%), Positives = 153/302 (50%), Gaps = 39/302 (12%)
Query: 43 IWRTKRFLDFIDRVGREHKGFWRIYGDIGIIA-------GFGGMAFVLYYFLKQAYNILR 95
I RTK L I+++G+ ++I+ IGII+ GF F+L + + +L
Sbjct: 38 ILRTKLGLKTIEKLGK-----YKIWQKIGIISIPICVILGF----FMLLNIIDMSIRLLS 88
Query: 96 PTAEVVPSVQLV-IPGVTIPLVYGLISLAVLIIVHELSHGFVARAENIPLKSVGLLFFIV 154
T + +V + G IP + G+I+L + I VHEL+HG A++ I +KS G+L +
Sbjct: 89 GTLPKEAAKPVVFLFGDVIPWIPGIIALLIAISVHELAHGIFAKSFGIKVKSSGILLLLG 148
Query: 155 LP-GAFVEPDEDELKKAPLRSRLRVFAAGSFANFIVAFISV-LVFNGVTLAFEPHGVEVF 212
LP GAFVE DE K A + R + +AG AN I+ S+ L+ TL E ++V
Sbjct: 149 LPLGAFVELG-DEFKTADKKIRGAIASAGPLANLIIFLTSIPLLSFSYTLPTELKIIDV- 206
Query: 213 GVIKDSPAYGILEKGDVIVEINGVKINTLEEFIKFMNNTKPGEELSLVILRNGKVKNISI 272
PA L+KGD+I EING KIN+LE+F +F +P +E + ILR+ K+ I
Sbjct: 207 ----KEPASEFLQKGDIIYEINGKKINSLEDFKEFAKTIEPKKEYEIKILRDNKILTYKI 262
Query: 273 TLGEHPERPGKGFIGIYPTQHLISKIGFDKELMVIFTLFYWLYVINFGVGLMNLLPVIPL 332
GK I + PT K + YW Y NF + L NLLP +PL
Sbjct: 263 V----SSNEGKLGIMVSPT----------KNTALFINTIYWTYWFNFLLALFNLLPAMPL 308
Query: 333 DG 334
DG
Sbjct: 309 DG 310
>gi|11498920 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7483116|pir||A69415 conserved hypothetical protein
AF1322 - Archaeoglobus fulgidus
>gi|2649254|gb|AAB89923.1| (AE001012) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 501
Score = 130 bits (324), Expect = 2e-29
Identities = 83/254 (32%), Positives = 143/254 (55%), Gaps = 27/254 (10%)
Query: 45 RTKRFLDFIDRVGREHKGFWRIYGDIGIIAGFGGMAFVLYYFLKQAYNIL----RPTAEV 100
RTK+ L+ ++++ R K FWR++ D+G+ A F GM F+ L Y +L +P+
Sbjct: 46 RTKKGLELLEKLSRP-KRFWRLFADLGLPAVFAGMVFMFSLILIADYIMLISPPQPSELT 104
Query: 101 VPSVQLVIPGVT--IPLVYGLISLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGA 158
P L++PGV IP+V+G I L V +IVHE SH + R E + +KS+G++ ++ G
Sbjct: 105 SPRAALLLPGVNPFIPIVWGTIGLVVTLIVHEFSHAILCRVEGVTVKSLGVILALIPIGG 164
Query: 159 FVEPDEDEL---KKAPLRSRLRVFAAGSFANFIVAFISVLVFNGVTLAFEPHGVEVFGVI 215
F EP+E E+ ++ +R+R+F+AG +NF VAFI+ +F + +P V +
Sbjct: 165 FAEPEEKEIMDKERTKSSARIRIFSAGVVSNFAVAFIAFALFFSLLPTVQPALV----AV 220
Query: 216 KDSPAYGILEKGDVIVEINGVKINTLEEFIKFMNNTKPGEELSLVILRNGKVKNISITLG 275
DS G++E IVE+NGVK++++++ + N + E + I+ +++ +S+
Sbjct: 221 NDS---GVVE--GRIVEVNGVKVSSVDDVKAVLQNAEIAE---IKIVNGDEIRILSV--- 269
Query: 276 EHPERPGKGFIGIY 289
P G IG+Y
Sbjct: 270 --PAVMGVKVIGLY 281
>emb|CAC12398.1| (AL445067) sterol-regulatory element-binding proteins intramembrane
protease related protein [Thermoplasma acidophilum]
Length = 511
Score = 97.9 bits (240), Expect = 2e-19
Identities = 74/265 (27%), Positives = 127/265 (47%), Gaps = 12/265 (4%)
Query: 18 WAVIGILGVTVLKDSKSLEIAPFQIIWRTKRFLDFIDRVGREH--KGFWRIYGDIGIIAG 75
W I L +K SK + I+ + + I+ + ++ K F ++ + IIAG
Sbjct: 14 WIAIVYLLSPYIKRSKHFSLFGPAIMLKFVKNRGVIEGISKKFPAKAFSKVSVIVVIIAG 73
Query: 76 FGGMAFVLYYFLKQAY--NILRPTAEVVPSVQLVIPGVT--IPLVYGLISLAVLIIVHEL 131
+ ++Y AY + +RP+ + L +PG+ IP+ YG+++L V ++VHE+
Sbjct: 74 IVALVSLIY----SAYLASFIRPSQAPPVTEFLGLPGINPVIPIGYGIVALVVSVVVHEM 129
Query: 132 SHGFVARAENIPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFAAGSFANFIVAF 191
HG A+ + + SVG+LFFIV GAFVEP+E E+ A R R+FAAG N I+
Sbjct: 130 MHGVTAKRHGLKVDSVGVLFFIVPVGAFVEPNETEMMSADPVIRRRIFAAGPGVNIIIGI 189
Query: 192 I-SVLVFNGVTLAFEPHGVEVFGVIKDSPAYGILEKGDVIVEINGVKINTLEEFIKFMNN 250
I ++L+ + + P V+ D + G+ I+ I N + + +N
Sbjct: 190 ILAILISTVMFSSAAPVHNGVYVQSSDPQVNPSIPAGNEIIAIGNYTGNNVTTAL-INSN 248
Query: 251 TKPGEELSLVILRNGKVKNISITLG 275
PG +++ + VK + G
Sbjct: 249 LAPGSNVNVSLFNGKNVKQVEAVAG 273
>gb|AAG20184.1| (AE005095) Vng2019c [Halobacterium sp. NRC-1]
Length = 600
Score = 94.8 bits (232), Expect = 2e-18
Identities = 84/295 (28%), Positives = 132/295 (44%), Gaps = 32/295 (10%)
Query: 10 VILGILGFWAVIGILGVTVLKDSKSLEIAPFQIIW--RTKRFLDFIDRVGREHKGFWRIY 67
+++G+L +WA + L S P + R KRFLD++ K WR +
Sbjct: 7 LLVGLLAYWAAVSWAQSRGLLPSFVHTSGPITTLHTKRGKRFLDWM----ATPKRLWRAW 62
Query: 68 GDIGI----IAGFGGMAFVLYYFLKQAYNILRPTAEVVPSVQLVIPGVT--IPLVYG--- 118
G+ G+ + G + ++ + N PT+ PS LVIPGV +PL
Sbjct: 63 GNFGLGLASVVLVGVLIALVLVAITTLLNPPEPTSISQPSNVLVIPGVNDFLPLSVAPEI 122
Query: 119 LISLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLP-GAFVEPDEDELKKAPLRSRLR 177
+ L + I++HE HG + R E I ++S+G+ VLP GAFVEPD+D A S+ R
Sbjct: 123 IAGLFIGIVIHEFGHGLMCRVEGIDVESMGVALLAVLPVGAFVEPDQDSQADADRGSKSR 182
Query: 178 VFAAGSFANFIVAFISV-LVFNGVTLAFEPHGVEVFGVIKDSPAYGI--LEKGDVIVEIN 234
+FAAG NF+V +++ L+F V A + G + D A GD I +
Sbjct: 183 MFAAGVTNNFLVVVVTLALLFGPVAGAVAVSDGGLVGEVHDGTAAAAAGFSGGDRITAVG 242
Query: 235 GVKI-------NTLEEF------IKFMNNTKPGEELSLVILRNGKVKNISITLGE 276
G + L+E+ + +N E L ++ N +SIT +
Sbjct: 243 GAPVANNTAFRQALDEYDDPTVPVTLASNETVRVERQLSVVANASNSPLSITTND 297
>pir||T05339 hypothetical protein F1C12.220 - Arabidopsis thaliana
>gi|2982448|emb|CAA18255.1| (AL022224) putative protein
[Arabidopsis thaliana] >gi|7268826|emb|CAB79031.1|
(AL161552) putative protein [Arabidopsis thaliana]
Length = 368
Score = 87.8 bits (214), Expect = 2e-16
Identities = 75/266 (28%), Positives = 119/266 (44%), Gaps = 41/266 (15%)
Query: 45 RTKRFLDFIDRVGREHKGFWRIYGDIGIIAGFGGMAFVLYYFLKQAYN----ILRPTAEV 100
+ F + I R+GR G +++ IG+ G + V + L Q ++ R T+ V
Sbjct: 38 KISNFNEPIFRLGRRFSGVLKVWFSIGLGFGVASLILVTVFLLLQFHSNPLFSNRLTSAV 97
Query: 101 V---PSVQLVIPGVTIPLVYGLISLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPG 157
PS ++ + G+ Y L+S + + VHEL H A +E I ++ + + + PG
Sbjct: 98 FGFSPSTRVSLSGIA----YVLVSTVITVSVHELGHALAAASEGIQMEYIAVFIAAIFPG 153
Query: 158 AFVEPDEDELKKAPLRSRLRVFAAGSFANFIVA-------FISVLVFNGVTL-----AFE 205
V D D L+ P + LR++ AG + N +V F ++ VF L F
Sbjct: 154 GLVAFDNDVLQSLPSFNALRIYCAGIWHNAVVGSSLSSFYFCALCVFALFLLPVMLSPFY 213
Query: 206 PHG--VEVFGVIKDSPAYGILEKGDVIVEINGVKINTLEEFIKFMNNTKPGEELSLVIL- 262
HG + V V SP +G L GDVIV ++G++++ KP E L L +
Sbjct: 214 KHGESLTVVDVPSVSPLFGYLSPGDVIVSLDGIQVH------------KPSEWLELAAIL 261
Query: 263 --RNGKVKNISITL-GEHPERPGKGF 285
N K N S+ L G GKG+
Sbjct: 262 DKENSKTSNGSLYLGGSRRFHHGKGY 287
>sp|O54862|MS2P_CRIGR STEROL-REGULATORY ELEMENT-BINDING PROTEINS INTRAMEMBRANE PROTEASE
(SITE-2 PROTEASE) >gi|2745731|gb|AAC53526.1| (AF019611)
S2P [Cricetulus griseus]
Length = 510
Score = 81.1 bits (197), Expect = 2e-14
Identities = 68/281 (24%), Positives = 116/281 (41%), Gaps = 46/281 (16%)
Query: 9 NVILGILGFWAVIGILGVTVLKDS-------------KSLEIAPFQIIWRTKRFLDFIDR 55
++++ ++G W + L VLK S L I+PF I W+T F
Sbjct: 5 SLVVVVVGGWTAV-YLADLVLKSSVYFKHSYEDWLEKNGLSISPFHIRWQTSVFNRAFYS 63
Query: 56 VGREHKGFWRIYGDIGIIAGFGGMAFVLYYFLKQAYNILRPTAEVVPS------------ 103
GR + + G++ G M + K L PS
Sbjct: 64 WGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSSSSSSSSSSSS 123
Query: 104 ----------VQLVIPGVTIP---LVYGLISLAVLIIVHELSHGFVARAENIPLKSVGLL 150
+Q+V+PG+ +P L Y ++ + +VHE+ HG A E + G+
Sbjct: 124 SSSSIHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIF 183
Query: 151 FFIVLPGAFVEPDEDELKKAPLRSRLRVFAAGSFANFIVAFISVLVFNGVTLAFEPH--- 207
FI+ PGAFV+ L+ +LR+F AG + NF++A + +L + + P
Sbjct: 184 LFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYT 243
Query: 208 --GVEVFGVIKDSPAYGI--LEKGDVIVEINGVKINTLEEF 244
GV + V +DSPA G L GD++ + + ++++
Sbjct: 244 GVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDW 284
>gi|7706693 S2P protein [Homo sapiens] >gi|6016601|sp|O43462|MS2P_HUMAN
STEROL-REGULATORY ELEMENT-BINDING PROTEINS INTRAMEMBRANE
PROTEASE (SITE-2 PROTEASE) >gi|2745733|gb|AAC51937.1|
(AF019612) S2P [Homo sapiens]
Length = 519
Score = 79.6 bits (193), Expect = 6e-14
Identities = 70/290 (24%), Positives = 124/290 (42%), Gaps = 55/290 (18%)
Query: 9 NVILGILGFWAVIGILGVTVLKDS-------------KSLEIAPFQIIWRTKRFLDFIDR 55
++++ ++G W V+ + + VLK S L I+PF I W+T F
Sbjct: 5 SLVVVVVGGWTVVYLTDL-VLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYS 63
Query: 56 VGREHK-------GFWRIYGDIGIIAGFGGMAFVLYYFLKQ-------AYNILRPTAEVV 101
GR F ++G I + + F + L L Q +Y+ ++
Sbjct: 64 WGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSS 123
Query: 102 PS-----------------VQLVIPGVTIP---LVYGLISLAVLIIVHELSHGFVARAEN 141
S +Q+V+PG+ +P L Y ++ + +VHE+ HG A E
Sbjct: 124 SSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQ 183
Query: 142 IPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFAAGSFANFIVAFISVLVFNGVT 201
+ G+ FI+ PGAFV+ L+ +LR+F AG + NF++A + +L +
Sbjct: 184 VRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLP 243
Query: 202 LAFEPH-----GVEVFGVIKDSPAYGI--LEKGDVIVEINGVKINTLEEF 244
+ P GV + V +DSPA G L GD++ + + ++++
Sbjct: 244 VILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDW 293
>gi|11419639 S2P protein [Homo sapiens]
Length = 552
Score = 79.6 bits (193), Expect = 6e-14
Identities = 70/290 (24%), Positives = 124/290 (42%), Gaps = 55/290 (18%)
Query: 9 NVILGILGFWAVIGILGVTVLKDS-------------KSLEIAPFQIIWRTKRFLDFIDR 55
++++ ++G W V+ + + VLK S L I+PF I W+T F
Sbjct: 38 SLVVVVVGGWTVVYLTDL-VLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYS 96
Query: 56 VGREHK-------GFWRIYGDIGIIAGFGGMAFVLYYFLKQ-------AYNILRPTAEVV 101
GR F ++G I + + F + L L Q +Y+ ++
Sbjct: 97 WGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSS 156
Query: 102 PS-----------------VQLVIPGVTIP---LVYGLISLAVLIIVHELSHGFVARAEN 141
S +Q+V+PG+ +P L Y ++ + +VHE+ HG A E
Sbjct: 157 SSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQ 216
Query: 142 IPLKSVGLLFFIVLPGAFVEPDEDELKKAPLRSRLRVFAAGSFANFIVAFISVLVFNGVT 201
+ G+ FI+ PGAFV+ L+ +LR+F AG + NF++A + +L +
Sbjct: 217 VRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLP 276
Query: 202 LAFEPH-----GVEVFGVIKDSPAYGI--LEKGDVIVEINGVKINTLEEF 244
+ P GV + V +DSPA G L GD++ + + ++++
Sbjct: 277 VILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDW 326
>gb|AAF58617.1| (AE003824) CG8988 gene product [Drosophila melanogaster]
Length = 481
Score = 78.4 bits (190), Expect = 1e-13
Identities = 48/164 (29%), Positives = 84/164 (50%), Gaps = 13/164 (7%)
Query: 104 VQLVIPGVTIPLV---YGLISLAVLIIVHELSHGFVARAENIPLKSVGLLFFIVLPGAFV 160
+++++PGV +PL Y + +L + ++VHE+ H A E++P+ G+ F LP A+
Sbjct: 95 LEILLPGVNLPLEEIGYYITTLVLCLVVHEMGHALAAVMEDVPVTGFGIKFIFCLPLAYT 154
Query: 161 EPDEDELKKAPLRSRLRVFAAGSFANFIVAFISVLVFNGVTLAFEP-----HGVEVFGVI 215
E D L +LRV AG + NF+ A + L+ + V + P V V +
Sbjct: 155 ELSHDHLNSLRWFRKLRVLCAGIWHNFVFAGVCYLLISTVGITMSPLYAYNQHVVVTELT 214
Query: 216 KDSPAYGI--LEKGDVIVEINGVKINTLEEFIKFMNNT---KPG 254
+ SP G L+ + I ++NG +N+ E ++ + N+ KPG
Sbjct: 215 RKSPLRGERGLQVDNQITQVNGCPVNSEESWVTCLQNSLKLKPG 258
>emb|CAB60513.1| (AL132860) predicted using Genefinder~contains similarity to Pfam
domain: PF02163 (Sterol-regulatory element binding
protein (SREBP) site 2 protease), Score=61.1,
E-value=7.9e-15, N=1~cDNA EST yk125f3.5 comes from this
gene [Caenorhabditis elegans]
Length = 585
Score = 70.6 bits (170), Expect = 3e-11
Identities = 44/158 (27%), Positives = 82/158 (51%), Gaps = 13/158 (8%)
Query: 107 VIPGVTIPLVYGLISLAVLIIV---HELSHGFVARAENIPLKSVGLLFFIVLPGAFVEPD 163
+IPG +P + I + VLI+ HEL H + A + + + G+ V PGAF + +
Sbjct: 200 IIPGFNLPWGHIPIFMLVLIVAAVFHELGHAWAATSNGVTVNGFGIFILAVYPGAFTDIE 259
Query: 164 EDELKKAPLRSRLRVFAAGSFANFIVAFISVLVFNGVTLAFEP-----HGVEVFGVIKDS 218
LK+A RL++F AG + N ++A +++ +F+ + P +GV V GV S
Sbjct: 260 AVTLKRATTFRRLQIFGAGIWHNLLLALLAMAMFHASPVILSPVLANGYGVSVRGVDVRS 319
Query: 219 ----PAYGILEKGDVIVEINGVKINTLEEFIKFMNNTK 252
P G++ GDV+ ++ ++ T+ ++ + + +K
Sbjct: 320 GLSNPRTGLV-AGDVVKSVDECRVETVADWWRCIRTSK 356
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.327 0.149 0.442
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141673651
Number of Sequences: 2977
Number of extensions: 6308499
Number of successful extensions: 21775
Number of sequences better than 1.0e-10: 16
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 21729
Number of HSP's gapped (non-prelim): 28
length of query: 378
length of database: 189,106,746
effective HSP length: 51
effective length of query: 327
effective length of database: 158,583,909
effective search space: 51856938243
effective search space used: 51856938243
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.6 bits)
S2: 166 (69.1 bits)