BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2199 (psmB) DE:proteasome, subunit beta (psmB)
(197 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75212 proteasome, chain beta (psmb) PAB2199 - Pyrococcus a... 390 e-108
pir||F71248 probable proteasome beta subunit - Pyrococcus horiko... 368 e-101
pir||D71013 probable proteasome beta subunit precursor - Pyrococ... 172 3e-42
sp|Q9UXF3|PRCB_SULSO PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT... 164 7e-40
emb|CAB57537.1| (Y18930) proteasome, beta subunit [Sulfolobus so... 164 7e-40
gb|AAK41063.1| Proteasome subunit [Sulfolobus solfataricus] 164 7e-40
sp|Q58634|PRCB_METJA PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT... 163 1e-39
pir||G75118 proteasome, chain beta PAB1867 - Pyrococcus abyssi (... 160 1e-38
pir||B72749 probable proteasome, beta subunit APE0521 - Aeropyru... 156 1e-37
gi|11498092 proteasome, subunit beta (psmB) [Archaeoglobus fulgi... 156 2e-37
sp|Q50534|PRCB_METTE PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT... 148 6e-35
sp|O27270|PRCB_METTH PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT... 143 2e-33
pir||T48677 proteasome beta-1 chain [validated] - Haloferax volc... 141 5e-33
sp|P28061|PRCB_THEAC PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT... 140 1e-32
pir||D72747 probable proteasome, beta subunit APE0507 - Aeropyru... 139 2e-32
gb|AAK40616.1| Proteasome subunit [Sulfolobus solfataricus] 125 3e-28
gb|AAG19322.1| (AE005027) proteasome, subunit alpha; PsmA [Halob... 125 5e-28
gb|AAF46978.1| (AE003460) CG9868 gene product [Drosophila melano... 103 2e-21
gi|4506193 proteasome (prosome, macropain) subunit, beta type, 1... 100 1e-20
gi|11419067 proteasome (prosome, macropain) subunit, beta type, ... 100 1e-20
dbj|BAA95591.1| (AB035496) 20S proteasome beta 6 subunit [Carass... 100 2e-20
dbj|BAA95592.1| (AB035497) 20S proteasome beta 6 subunit [Carass... 100 2e-20
gi|7242197 proteasome (prosome, macropain) subunit, beta type 1 ... 99 4e-20
emb|CAA56702.1| (X80686) component C5 of proteasome [Mus musculus] 99 4e-20
sp|P18421|PRC5_RAT PROTEASOME COMPONENT C5 (MACROPAIN SUBUNIT C5... 96 4e-19
pir||S21126 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 94 1e-18
sp|P28064|PRCY_RAT PROTEASOME COMPONENT C13 PRECURSOR (MACROPAIN... 94 1e-18
sp|O24361|PRCE_SPIOL PROTEASOME EPSILON CHAIN PRECURSOR (MACROPA... 92 4e-18
sp|Q60177|PRCA_METJA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 92 4e-18
gb|AAD22390.1|AF059493_1 (AF059493) proteasome subunit LMP7 [Sus... 92 6e-18
dbj|BAB02194.1| (AP001298) proteasome epsilon chain precursor [A... 92 6e-18
gb|AAC97957.1| (AF104214) proteasome beta 5 subunit [Trypanosoma... 91 1e-17
gi|6325360 proteasome subunit; Pre2p [Saccharomyces cerevisiae] ... 91 1e-17
gi|4758970 proteasome (prosome, macropain) subunit, beta type, 8... 91 1e-17
pir||C44324 proteasome chain LMP7 precursor, splice form E1 - hu... 91 1e-17
gb|AAA34906.1| (M96667) proteosome-related protein [Saccharomyce... 91 1e-17
pir||G01564 proteasome chain LMP7 precursor, splice form E2 - hu... 91 1e-17
gb|AAA56778.1| (U17497) proteasome subunit LMP7 [Homo sapiens] 91 1e-17
sp|P28062|PRCY_HUMAN PROTEASOME COMPONENT C13 PRECURSOR (MACROPA... 91 1e-17
sp|O23717|PRCE_ARATH PROTEASOME EPSILON CHAIN PRECURSOR (MACROPA... 91 1e-17
dbj|BAA28276.1| (AB014058) beta 6 subunit of 20S proteasome [Ory... 91 1e-17
pir||I51536 XeLMPa.aa - African clawed frog >gi|971307|dbj|BAA07... 90 1e-17
dbj|BAA10932.1| (D64055) LMPX of lamprey [Petromyzon marinus] 89 3e-17
dbj|BAA19767.1| (D89725) LMP7 [Oryzias latipes] 89 3e-17
pir||T40487 proteasome component precursor - fission yeast (Sch... 89 3e-17
dbj|BAA96838.1| (AB026567) beta 5 subunit of 20S proteasome [Ory... 89 3e-17
gi|4506191 proteasome (prosome, macropain) subunit, beta type, 1... 89 5e-17
gb|AAB86994.1| (U77784) Lmp10 proteasome subunit [Mus musculus] ... 89 5e-17
pdb|1G0U|K Chain K, A Gated Channel Into The Proteasome Core Par... 89 5e-17
sp|P28063|PRCY_MOUSE PROTEASOME COMPONENT C13 PRECURSOR (MACROPA... 88 6e-17
emb|CAA45780.1| (X64449) proteasome subunit MC13 [Mus musculus] 88 6e-17
gb|AAA75035.1| (U22033) 20S proteasome subunit Lmp7 [Mus musculu... 88 6e-17
gb|AAA75037.1| (U22035) 20S proteasome subunit Lmp7 [Mus musculus] 88 6e-17
gi|7305417 proteasome (prosomome, macropain) subunit, beta type ... 88 6e-17
gi|6755208 proteosome (prosome, macropain) subunit, beta type 8 ... 88 6e-17
gb|AAF37285.1|AF226674_1 (AF226674) 20S proteasome beta 5 subuni... 88 6e-17
emb|CAC08538.1| (AJ132959) proteasome PRCE (beta-5) subunit prec... 88 6e-17
pir||I52906 proteasome subunit MB1 - human (fragment) >gi|786582... 88 8e-17
dbj|BAA10934.1| (D64057) LMP7 [Ginglymostoma cirratum] 88 8e-17
gb|AAF72737.1|AF097521_1 (AF097521) proteasome B type subunit [C... 88 8e-17
pir||I51537 XeLMPb.aa - African clawed frog >gi|971309|dbj|BAA07... 87 1e-16
pdb|1RYP|L Chain L, Crystal Structure Of The 20s Proteasome From... 87 1e-16
pdb|1G65|K Chain K, Crystal Structure Of Epoxomicin:20s Proteaso... 87 2e-16
gb|AAF26416.1|AF217726_1 (AF217726) 20S proteasome beta5 subunit... 87 2e-16
gb|AAF58748.1| (AE003828) Prosbeta5 gene product [Drosophila mel... 87 2e-16
dbj|BAA96834.1| (AB026563) beta 1 subunit of 20S proteasome [Ory... 87 2e-16
sp|P28075|PRCE_RAT PROTEASOME EPSILON CHAIN PRECURSOR (MACROPAIN... 86 2e-16
sp|P28074|PRCE_HUMAN PROTEASOME EPSILON CHAIN PRECURSOR (MACROPA... 86 3e-16
gi|4506201 proteasome (prosome, macropain) subunit, beta type, 5... 86 3e-16
pir||S30539 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 85 4e-16
dbj|BAA10933.1| (D64056) LMP7 of nurse shark [Ginglymostoma cirr... 85 4e-16
sp|P93395|PRCD_TOBAC PROTEASOME DELTA CHAIN PRECURSOR (MULTICATA... 85 4e-16
sp|P34065|PRCE_CHICK PROTEASOME CHAIN 1 PRECURSOR (MACROPAIN CHA... 85 4e-16
pir||T43887 proteasome alpha chain [imported] - Thermococcus sp ... 85 4e-16
gb|AAF46088.1| (AE003435) CG18341 gene product [Drosophila melan... 85 4e-16
pir||T47893 proteasome component C5 - Arabidopsis thaliana >gi|5... 85 6e-16
sp|P42742|PRC5_ARATH PROTEASOME COMPONENT C5 (MULTICATALYTIC END... 85 6e-16
gi|6755204 proteasome beta type subunit 5 [Mus musculus] >gi|289... 85 7e-16
sp|O55234|PRCE_MOUSE PROTEASOME EPSILON CHAIN PRECURSOR (MACROPA... 85 7e-16
pir||B75181 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 85 7e-16
pir||JS0753 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 84 9e-16
sp|P30655|PRCE_SCHPO PROTEASOME COMPONENT PTS1 PRECURSOR (MACROP... 84 9e-16
dbj|BAA10935.1| (D64058) nurse shark LMPX [Ginglymostoma cirratum] 84 1e-15
gb|AAD53521.1|AF155581_1 (AF155581) proteasome subunit beta 7 [D... 84 1e-15
pir||T04497 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 83 2e-15
gb|AAB87679.1| (AF032390) LMP7 [Danio rerio] 83 2e-15
gb|AAD53518.1|AF155578_1 (AF155578) proteasome subunit beta 5 [D... 83 2e-15
emb|CAB96046.1| (AJ404677) proteasome beta 2 subunit [Giardia in... 83 2e-15
gb|AAG16286.1|AC016024_9 (AC016024) leishmania proteasome subuni... 83 2e-15
emb|CAC13117.1| (AJ271723) low molecular mass polypeptide subuni... 83 2e-15
gi|6755206 proteasome (prosome, macropain) subunit, beta type 7 ... 82 5e-15
emb|CAA67761.1| (X99382) alpha proteasome [Entamoeba histolytica] 82 5e-15
gb|AAF22654.1| (AF214525) interferon-gamma inducible proteasome ... 82 5e-15
gb|AAF97811.1|AF285103_1 (AF285103) proteasome z subunit [Rattus... 82 5e-15
emb|CAA10208.1| (AJ130820) proteasome subunit beta-2 [Trypanosom... 82 6e-15
sp|O59219|PRCA_PYRHO PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 81 8e-15
gb|AAD53517.1|AF155577_1 (AF155577) proteasome subunit beta 12 [... 81 1e-14
gi|4506203 proteasome (prosome, macropain) subunit, beta type, 7... 80 1e-14
pir||JC5073 proteasome epsilon chain precursor - Geodia cydonium... 80 1e-14
gb|AAC32060.1| (AF043524) 20S proteasome subunit PAE1 [Arabidops... 80 2e-14
dbj|BAA96832.1| (AB026561) alpha 5 subunit of 20S proteasome [Or... 79 3e-14
emb|CAA66313.1| (X97729) LMP7-like protein [Botryllus schlosseri] 79 4e-14
pir||JC5074 proteasome epsilon chain precursor - Botryllus schlo... 79 4e-14
gb|AAC32061.1| (AF043525) 20S proteasome subunit PAE2 [Arabidops... 78 5e-14
gb|AAC35983.1| (AF088915) proteasome beta subunit [Petunia x hyb... 78 5e-14
dbj|BAA19759.1| (D87687) LMP2 [Xenopus laevis] 78 7e-14
emb|CAA05209.1| (AJ002142) proteasome Z subunit [Ciona intestina... 78 7e-14
sp|O26782|PRCA_METTH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 78 7e-14
emb|CAC13118.1| (AJ271723) low molecular mass polypeptide subuni... 78 7e-14
sp|P34286|YKK9_CAEEL HYPOTHETICAL 63.1 KD PROTEIN C02F5.9 IN CHR... 78 9e-14
sp|P40304|PRC5_DROME PROTEASOME 26 KD SUBUNIT (MULTICATALYTIC EN... 78 9e-14
gi|11498101 proteasome, subunit alpha (psmA) [Archaeoglobus fulg... 78 9e-14
gb|AAF49435.1| (AE003526) Pros26 gene product [Drosophila melano... 78 9e-14
emb|CAC13120.1| (AJ271723) low molecular mass polypeptide subuni... 78 9e-14
gb|AAF70292.1|AF255338_1 (AF255338) 20S proteasome subunit [Glyc... 76 2e-13
sp|Q59565|PRCA_METTE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 75 8e-13
gi|6755202 proteasome (prosome, macropain) subunit, beta type, 3... 75 8e-13
gb|AAD53516.1|AF155576_1 (AF155576) proteasome subunit beta 11 [... 75 8e-13
gb|AAF49685.1| (AE003532) Prosbeta2 gene product [Drosophila mel... 75 8e-13
gi|8394082 proteasome (prosome, macropain) subunit, beta type, 3... 74 1e-12
gb|AAC32074.1| (AF043538) 20S proteasome beta subunit PBG1 [Arab... 74 1e-12
gb|AAC64284.1|AAC64284 (AF086832) 20S proteasome beta-subunit pr... 74 1e-12
dbj|BAA96835.1| (AB026564) beta 2 subunit of 20S proteasome [Ory... 74 1e-12
gb|AAC32067.1| (AF043531) 20S proteasome beta subunit PBB2 [Arab... 74 1e-12
gb|AAG26927.1|AC058785_3 (AC058785) 20S proteasome beta subunit ... 74 1e-12
sp|O73817|PRCT_ONCMY PROTEASOME THETA CHAIN (MACROPAIN THETA CHA... 73 2e-12
gi|6324731 putative proteasome subunit; Pup1p [Saccharomyces cer... 73 2e-12
sp|P25156|PRCA_THEAC PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 73 3e-12
gi|4506197 proteasome (prosome, macropain) subunit, beta type, 3... 73 3e-12
emb|CAA73621.1| (Y13178) multicatalytic endopeptidase [Arabidops... 73 3e-12
gb|AAC32066.1| (AF043530) 20S proteasome beta subunit PBB1 [Arab... 73 3e-12
gb|AAD31877.1|AF140353_1 (AF140353) 20S proteasome alpha 5 subun... 73 3e-12
gi|11424309 similar to proteasome (prosome, macropain) subunit, ... 73 3e-12
gb|AAB82570.1| (AF025791) 20S proteasome beta2 subunit [Drosophi... 72 5e-12
gb|AAB82571.1| (AF025792) 20S proteasome beta2 subunit [Drosophi... 72 5e-12
gb|AAC45736.1| (U26422) proteasome beta-type subunit 2 [Rhodococ... 71 9e-12
gb|AAD53037.1|AF115540_1 (AF115540) low molecular mass protein 2... 71 1e-11
sp|Q09841|PRCF_SCHPO PUTATIVE PROTEASOME COMPONENT PUP1 PRECURSO... 69 3e-11
dbj|BAA19146.1| (AB000540) proteasome component PUP1 precursor [... 69 3e-11
gb|AAD53519.1|AF155579_1 (AF155579) proteasome subunit beta 9A [... 69 3e-11
pir||T48678 proteasome alpha-1 chain [validated] - Haloferax vol... 69 4e-11
dbj|BAA96839.1| (AB026568) beta 7 subunit of 20S proteasome [Ory... 69 4e-11
emb|CAA74026.1| (Y13692) multicatalytic endopeptidase complex, p... 69 5e-11
pdb|1G65|H Chain H, Crystal Structure Of Epoxomicin:20s Proteaso... 69 5e-11
gb|AAF58077.1| (AE003808) CG8392 gene product [Drosophila melano... 69 5e-11
emb|CAB86711.1| (AL163505) 20S proteasome alpha 5 subunit [Leish... 69 5e-11
gi|6322459 Subunit of 20S proteasome; Pre3p [Saccharomyces cerev... 68 6e-11
dbj|BAA19761.1| (D87690) proteasome subunit Y [Lampetra japonica] 68 8e-11
dbj|BAA19766.1| (D89724) LMP2 [Oryzias latipes] 68 8e-11
pir||T23336 hypothetical protein K05C4.1 - Caenorhabditis elegan... 68 8e-11
dbj|BAA76428.1| (AB025000) multicatalytic endopeptidase complex ... 68 8e-11
pir||T48679 proteasome alpha-2 chain [validated] - Haloferax vol... 68 8e-11
>pir||H75212 proteasome, chain beta (psmb) PAB2199 - Pyrococcus abyssi (strain
Orsay) >gi|5457660|emb|CAB49151.1| (AJ248283)
proteasome, subunit beta (psmB) [Pyrococcus abyssi]
Length = 197
Score = 390 bits (992), Expect = e-108
Identities = 197/197 (100%), Positives = 197/197 (100%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM
Sbjct: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLD 120
IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLD
Sbjct: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLD 120
Query: 121 PLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKI 180
PLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKI
Sbjct: 121 PLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKI 180
Query: 181 QVVTITKDGMKEEFVTL 197
QVVTITKDGMKEEFVTL
Sbjct: 181 QVVTITKDGMKEEFVTL 197
>pir||F71248 probable proteasome beta subunit - Pyrococcus horikoshii
>gi|3256634|dbj|BAA29317.1| (AP000001) 197aa long
hypothetical proteasome beta subunit [Pyrococcus
horikoshii]
Length = 197
Score = 368 bits (934), Expect = e-101
Identities = 181/197 (91%), Positives = 193/197 (97%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
MNRKTGTTTVGI+VKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM
Sbjct: 1 MNRKTGTTTVGIKVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLD 120
IARILEAEARYY F WGRPMTT+AMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLD
Sbjct: 61 IARILEAEARYYYFAWGRPMTTKAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLD 120
Query: 121 PLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKI 180
P GGLIFD+YTATGSGTPFAIAILEEGY++NLGIE+AKELAIKA+KAAG+RDVYTGSKK+
Sbjct: 121 PYGGLIFDNYTATGSGTPFAIAILEEGYKENLGIEEAKELAIKAIKAAGSRDVYTGSKKV 180
Query: 181 QVVTITKDGMKEEFVTL 197
QVVTITK+GM+EEF+ L
Sbjct: 181 QVVTITKEGMQEEFIKL 197
>pir||D71013 probable proteasome beta subunit precursor - Pyrococcus horikoshii
>gi|3257825|dbj|BAA30508.1| (AP000006) 207aa long
hypothetical proteasome beta subunit precursor
[Pyrococcus horikoshii]
Length = 207
Score = 172 bits (431), Expect = 3e-42
Identities = 88/187 (47%), Positives = 127/187 (67%), Gaps = 1/187 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTTVGI KDGV+LAAD +ASL +++ N+ KI I + +AI AG VGD+ + R+L
Sbjct: 10 GTTTVGIVCKDGVVLAADRRASLGNIIYARNVTKIHKIDEHLAIAGAGDVGDILNLVRLL 69
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGGL 125
AEA+ Y G+ M+ +A+A LL+NI+N K+FPYL ++GGY ++P + ++D +GG+
Sbjct: 70 RAEAKLYYSQSGKRMSVKALATLLANIMNGAKYFPYLAWFLVGGYDEKPKLYSVDMVGGI 129
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTI 185
D Y GSG FA +IL+ Y+ NL +E+ +LA+KA+ A RDV++G I VVTI
Sbjct: 130 TEDKYATAGSGMEFAYSILDSEYKDNLTLEEGIKLAVKAINTAIKRDVFSGD-GILVVTI 188
Query: 186 TKDGMKE 192
TK+G KE
Sbjct: 189 TKEGYKE 195
>sp|Q9UXF3|PRCB_SULSO PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX BETA SUBUNIT)
Length = 208
Score = 164 bits (411), Expect = 7e-40
Identities = 88/187 (47%), Positives = 125/187 (66%), Gaps = 1/187 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTTVGIRV DGVILAAD +AS V +RK++ ITD+I ITTAGSV D+Q I +L
Sbjct: 14 GTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVL 73
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGGL 125
+ Y T P++ + +A L+N+L+ K+FPY+VQI+IGGY D+P + NLD LG +
Sbjct: 74 KNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDI 133
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTI 185
++Y ATGSG+P A+ +LE+ Y + +++A +LA +AV +A RD +TG+ I V I
Sbjct: 134 TEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVI-VAKI 192
Query: 186 TKDGMKE 192
G +E
Sbjct: 193 HSKGHEE 199
>emb|CAB57537.1| (Y18930) proteasome, beta subunit [Sulfolobus solfataricus]
Length = 225
Score = 164 bits (411), Expect = 7e-40
Identities = 88/187 (47%), Positives = 125/187 (66%), Gaps = 1/187 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTTVGIRV DGVILAAD +AS V +RK++ ITD+I ITTAGSV D+Q I +L
Sbjct: 31 GTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVL 90
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGGL 125
+ Y T P++ + +A L+N+L+ K+FPY+VQI+IGGY D+P + NLD LG +
Sbjct: 91 KNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDI 150
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTI 185
++Y ATGSG+P A+ +LE+ Y + +++A +LA +AV +A RD +TG+ I V I
Sbjct: 151 TEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVI-VAKI 209
Query: 186 TKDGMKE 192
G +E
Sbjct: 210 HSKGHEE 216
>gb|AAK41063.1| Proteasome subunit [Sulfolobus solfataricus]
Length = 225
Score = 164 bits (411), Expect = 7e-40
Identities = 88/187 (47%), Positives = 125/187 (66%), Gaps = 1/187 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTTVGIRV DGVILAAD +AS V +RK++ ITD+I ITTAGSV D+Q I +L
Sbjct: 31 GTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVL 90
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGGL 125
+ Y T P++ + +A L+N+L+ K+FPY+VQI+IGGY D+P + NLD LG +
Sbjct: 91 KNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDI 150
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTI 185
++Y ATGSG+P A+ +LE+ Y + +++A +LA +AV +A RD +TG+ I V I
Sbjct: 151 TEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVI-VAKI 209
Query: 186 TKDGMKE 192
G +E
Sbjct: 210 HSKGHEE 216
>sp|Q58634|PRCB_METJA PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX BETA SUBUNIT) >gi|2129223|pir||D64454 proteasome
beta subunit homolog - Methanococcus jannaschii
>gi|1591869|gb|AAB99241.1| (U67564) proteasome, subunit
beta (psmB) [Methanococcus jannaschii]
Length = 224
Score = 163 bits (409), Expect = 1e-39
Identities = 91/194 (46%), Positives = 130/194 (66%), Gaps = 4/194 (2%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
M+ GTTTVG+ D VILA D +ASL ++V +K+ I D IA+T AGSVGD Q
Sbjct: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY--VDEPTIAN 118
I R+L AEA+ Y+ GR + A A LLSNIL+ ++ FP+L QIIIGGY ++ + +
Sbjct: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120
Query: 119 LDPLGGLIFD-DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGS 177
LDPLGG+ + +TATGSG+P A +LE GY +++ +E+ +LA+ A+K+A RD ++G+
Sbjct: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180
Query: 178 KKIQVVTITKDGMK 191
I + ITKDG+K
Sbjct: 181 -GISLAVITKDGVK 193
>pir||G75118 proteasome, chain beta PAB1867 - Pyrococcus abyssi (strain Orsay)
>gi|5458175|emb|CAB49664.1| (AJ248285) proteasome,
subunit beta [Pyrococcus abyssi]
Length = 207
Score = 160 bits (400), Expect = 1e-38
Identities = 80/187 (42%), Positives = 126/187 (66%), Gaps = 1/187 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTTVGI DGV+LAAD +ASL ++V N+ KI I + +AI AG VGD+ + R+L
Sbjct: 10 GTTTVGIVCSDGVVLAADRRASLGNIVYAKNVTKIHKIDEHLAIAGAGDVGDILNLVRLL 69
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGGL 125
AEA+ Y G+ M+ +A+A LL+N+LN + PYL ++GG+ ++P + ++D +GG+
Sbjct: 70 RAEAKLYYAQSGKRMSVKALATLLANMLNGARMLPYLAWFLVGGFDEKPRLYSVDMMGGI 129
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTI 185
D Y A GSG FA ++L+ YR++L + + ++A++A+ +A RDV++G I VVTI
Sbjct: 130 TEDKYVAAGSGMEFAYSVLDSEYREDLKVREGIKIAVEAINSAIKRDVFSGD-GIMVVTI 188
Query: 186 TKDGMKE 192
T++G +E
Sbjct: 189 TEEGYRE 195
>pir||B72749 probable proteasome, beta subunit APE0521 - Aeropyrum pernix
(strain K1) >gi|5104170|dbj|BAA79486.1| (AP000059) 225aa
long hypothetical proteasome, beta subunit [Aeropyrum
pernix]
Length = 225
Score = 156 bits (391), Expect = 1e-37
Identities = 79/192 (41%), Positives = 127/192 (66%), Gaps = 1/192 (0%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
++GTTTVG+ D VILAAD +A+ ++ + ++KI+ +++ +A+T +G V D Q+++
Sbjct: 29 RSGTTTVGLIASDHVILAADKRATAGFLIASRRVKKIVMLSNYVAMTVSGLVADAQILSD 88
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
+L E R Y+ T + R +A+LLSNIL +K+FPY+VQ+I+GGY +P + LD G
Sbjct: 89 VLREEIRLYEMTNKVKPSVRFVASLLSNILFSSKFFPYIVQLIVGGYDTQPRLYTLDLFG 148
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ D YTATGSG+P A +LEE YR++L +E+A ++A A+++A RD +G VV
Sbjct: 149 SITEDKYTATGSGSPIAYGVLEERYREDLSVEEAIKVATTAIRSAVLRDAASGD-GADVV 207
Query: 184 TITKDGMKEEFV 195
I G +E+F+
Sbjct: 208 VIGPQGYEEKFI 219
>gi|11498092 proteasome, subunit beta (psmB) [Archaeoglobus fulgidus]
>gi|6093784|sp|O29769|PRCB_ARCFU PROTEASOME BETA SUBUNIT
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX BETA SUBUNIT)
>gi|7435875|pir||A69310 proteasome, subunit beta (psmB)
homolog - Archaeoglobus fulgidus
>gi|2650155|gb|AAB90757.1| (AE001071) proteasome,
subunit beta (psmB) [Archaeoglobus fulgidus]
Length = 213
Score = 156 bits (390), Expect = 2e-37
Identities = 84/185 (45%), Positives = 126/185 (67%), Gaps = 3/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTTVG+ KDGV++A + +A++ + + + +KI I DR+A+TTAGSVGD Q +ARI+
Sbjct: 11 GTTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARII 70
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ EA Y+ R T RA+A L SN+LN ++FPYLVQ++IGG E +I ++DP+GG
Sbjct: 71 KIEANLYEIRRERKPTVRAIATLTSNLLNSYRYFPYLVQLLIGGIDSEGKSIYSIDPIGG 130
Query: 125 LIFD-DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
I + D ATGSG+ A +LE+ + +G+++A ELA++A+ +A RD +G I VV
Sbjct: 131 AIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGD-GIDVV 189
Query: 184 TITKD 188
IT+D
Sbjct: 190 KITED 194
>sp|Q50534|PRCB_METTE PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX BETA SUBUNIT) >gi|11265945|pir||T48879
proteasome psmB, beta chain - Methanosarcina thermophila
>gi|790625|gb|AAA91642.1| (U22157) beta-type proteasome
subunit [Methanosarcina thermophila]
Length = 210
Score = 148 bits (369), Expect = 6e-35
Identities = 76/189 (40%), Positives = 125/189 (65%), Gaps = 5/189 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTTVG+ DG++LA++ +A++ H + + +K+ I D + +TTAGSVGD Q + R++
Sbjct: 9 GTTTVGVVCTDGIVLASEQRATMGHFIASKTAKKVYQIDDLVGMTTAGSVGDAQQLVRLV 68
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
E++ Y+ MT + + L+SN L+ N+++P +VQ++IGG VD+ P I +LD +G
Sbjct: 69 SVESQLYKMRRDESMTIKGITTLMSNFLSRNRYYPMMVQLLIGG-VDKNGPGIYSLDAMG 127
Query: 124 GLIFDD-YTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G I + +ATGSG+P A +LE+ YR+N+ +++ +LAI+A+ A RD +G + I V
Sbjct: 128 GSIEETRISATGSGSPMAYGVLEDQYRENMTVKEGLDLAIRAIHNATKRDSASG-ENIDV 186
Query: 183 VTITKDGMK 191
V ITK+ K
Sbjct: 187 VVITKEAFK 195
>sp|O27270|PRCB_METTH PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX BETA SUBUNIT) >gi|7435876|pir||E69027
proteasome, beta subunit - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622311|gb|AAB85691.1| (AE000888) proteasome, beta
subunit [Methanobacterium thermoautotrophicum]
Length = 210
Score = 143 bits (356), Expect = 2e-33
Identities = 78/189 (41%), Positives = 122/189 (64%), Gaps = 4/189 (2%)
Query: 2 NRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMI 61
N GTTTVGI KDGV+ A + +AS+ +++ KI I + IA T AGSV D Q +
Sbjct: 5 NTLKGTTTVGITCKDGVVFATERRASMGNLIAHKATDKIFKIDEHIAATIAGSVADAQSL 64
Query: 62 ARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANL 119
+ L+AEA Y+ ++ A A L +NIL+ ++++P++VQ ++GG VDE I +L
Sbjct: 65 MKYLKAEAALYRMRNSEKISIEAAAALAANILHSSRFYPFIVQTLLGG-VDENGAKIYSL 123
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
DP GG+I D + +TGSG+P A +LE+ Y L +++A ++AI+A+K+A RD Y+G+
Sbjct: 124 DPSGGMIPDKFVSTGSGSPVAYGVLEDRYSDELYVDEAVDVAIRAIKSAMERDTYSGN-G 182
Query: 180 IQVVTITKD 188
I V T+T++
Sbjct: 183 ILVATVTEE 191
>pir||T48677 proteasome beta-1 chain [validated] - Haloferax volcanii
>gi|5833210|gb|AAD53406.1|AF126262_1 (AF126262) beta-1
subunit of 20S proteasome [Haloferax volcanii]
Length = 243
Score = 141 bits (352), Expect = 5e-33
Identities = 77/189 (40%), Positives = 124/189 (64%), Gaps = 6/189 (3%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTTTVGI+ ++GV+LA D +AS+ +MV + +++K+ I A+T AGSV Q +
Sbjct: 47 KTGTTTVGIKTEEGVVLATDMRASMGYMVSSKDVQKVEEIHPTGALTIAGSVSAAQSLIS 106
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDP 121
L AE R Y+ G M+ +A++ L+ N L + Y+VQ I+GG VDE P I ++DP
Sbjct: 107 SLRAEVRLYEARRGEDMSMQALSTLVGNFLRSGGF--YVVQPILGG-VDETGPHIYSIDP 163
Query: 122 LGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G ++ ++YT TGSG+ +A+ +LE+ + L IE+AK +A KA+++A RD+ +G+ I
Sbjct: 164 AGSILEEEYTVTGSGSQYALGVLEQEFEDGLSIEEAKGVATKAIRSAVERDLASGN-GIN 222
Query: 182 VVTITKDGM 190
+ +T+DG+
Sbjct: 223 IAVVTEDGV 231
>sp|P28061|PRCB_THEAC PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX BETA SUBUNIT) >gi|282687|pir||A42068 proteasome
beta chain - Thermoplasma acidophilum
>gi|1633385|pdb|1PMA|1 Chain 1, Proteasome From
Thermoplasma Acidophilum >gi|1633386|pdb|1PMA|2 Chain 2,
Proteasome From Thermoplasma Acidophilum
>gi|1633360|pdb|1PMA|B Chain B, Proteasome From
Thermoplasma Acidophilum >gi|1633374|pdb|1PMA|P Chain P,
Proteasome From Thermoplasma Acidophilum
>gi|1633375|pdb|1PMA|Q Chain Q, Proteasome From
Thermoplasma Acidophilum >gi|1633376|pdb|1PMA|R Chain R,
Proteasome From Thermoplasma Acidophilum
>gi|1633377|pdb|1PMA|S Chain S, Proteasome From
Thermoplasma Acidophilum >gi|1633378|pdb|1PMA|T Chain T,
Proteasome From Thermoplasma Acidophilum
>gi|1633379|pdb|1PMA|U Chain U, Proteasome From
Thermoplasma Acidophilum >gi|1633380|pdb|1PMA|V Chain V,
Proteasome From Thermoplasma Acidophilum
>gi|1633381|pdb|1PMA|W Chain W, Proteasome From
Thermoplasma Acidophilum >gi|1633382|pdb|1PMA|X Chain X,
Proteasome From Thermoplasma Acidophilum
>gi|1633383|pdb|1PMA|Y Chain Y, Proteasome From
Thermoplasma Acidophilum >gi|1633384|pdb|1PMA|Z Chain Z,
Proteasome From Thermoplasma Acidophilum
>gi|154680|gb|AAA72102.1| (M83674) proteasome
beta-subunit [Thermoplasma acidophilum]
>gi|10639779|emb|CAC11751.1| (AL445064) proteasome, beta
chain [Thermoplasma acidophilum]
Length = 211
Score = 140 bits (349), Expect = 1e-32
Identities = 70/186 (37%), Positives = 112/186 (59%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
+TGTTTVGI +KD VI+A + + ++++ + N +K+ I +T AG VGD Q++ R
Sbjct: 6 ETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVR 65
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
++AE Y+ M A+A LLSN+LN+ K+ PY+VQ+++GG P + ++D G
Sbjct: 66 YMKAELELYRLQRRVNMPIEAVATLLSNMLNQVKYMPYMVQLLVGGIDTAPHVFSIDAAG 125
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
G + D Y +TGSG+PF +LE Y + + +++ +L I+A+ AA RD +G V
Sbjct: 126 GSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMIDVAV 185
Query: 184 TITKDG 189
KDG
Sbjct: 186 ITRKDG 191
>pir||D72747 probable proteasome, beta subunit APE0507 - Aeropyrum pernix
(strain K1) >gi|5104156|dbj|BAA79472.1| (AP000059) 239aa
long hypothetical proteasome, beta subunit [Aeropyrum
pernix]
Length = 239
Score = 139 bits (348), Expect = 2e-32
Identities = 74/174 (42%), Positives = 110/174 (62%), Gaps = 4/174 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T +GIRV+DGV+LAAD + S + + N +KI I DRI I AG GD+ + RI+
Sbjct: 41 GATALGIRVEDGVVLAADKRMSYGGFILSRNFKKIFVINDRIGIAFAGLYGDMGGLVRIV 100
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVD---EPTIANLDPL 122
E + R G+P T R +A LS++L K+FP+ V+ I+GG +D EP + LDPL
Sbjct: 101 EGQMRLASLETGKPATVRNVAKFLSSLLYSYKFFPFNVEAIVGG-IDPGGEPKLYVLDPL 159
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
G +I +DY A G+G A +LE Y++ + +E+AK+ A++A++A+ ARD TG
Sbjct: 160 GSIIEEDYVAAGTGATTAFGLLEHVYKRGMSLEEAKKAAVEALRASMARDAGTG 213
>gb|AAK40616.1| Proteasome subunit [Sulfolobus solfataricus]
Length = 196
Score = 125 bits (312), Expect = 3e-28
Identities = 72/187 (38%), Positives = 112/187 (59%), Gaps = 5/187 (2%)
Query: 8 TTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILEA 67
T VG++V DG++LA++ + S V + +K+ I ++ + AG GD+Q + RI+
Sbjct: 7 TAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKI-NKFLMAGAGIYGDLQTLTRIMNV 65
Query: 68 EARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLGGL 125
E +YY+ + G+P++ A A LLS IL + K P++ +I+ GG VDE P + LDP+G L
Sbjct: 66 EIKYYEVSTGKPISVHAAAKLLSVILYQYKVMPFISEILFGG-VDEKGPQLYVLDPIGSL 124
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTI 185
I D+Y A GSG AI +LE Y N+ ++ A +L KA+KA+ RD+ +G I + I
Sbjct: 125 IEDNYAAVGSGARIAIGVLESEYDPNMSLDVATQLITKAIKASIERDITSGD-GIDLAII 183
Query: 186 TKDGMKE 192
K G E
Sbjct: 184 DKKGNYE 190
>gb|AAG19322.1| (AE005027) proteasome, subunit alpha; PsmA [Halobacterium sp.
NRC-1]
Length = 255
Score = 125 bits (310), Expect = 5e-28
Identities = 73/189 (38%), Positives = 114/189 (59%), Gaps = 5/189 (2%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLD-HMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
KTGTT VG+ +DGV++A+D +ASL ++ N++K+ I A++ +GSVG Q
Sbjct: 58 KTGTTIVGLTTQDGVLMASDMRASLGGRVISNKNVQKVEEIQPNAALSISGSVGGAQSFI 117
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPT-IANLDP 121
R L AEA Y+ G M+ A++ + SN+L +F V I+GG D+ + +LDP
Sbjct: 118 RSLRAEANLYEARRGEYMSIDALSTMASNLLRGGPFFR--VVPILGGVDDDGGHVFSLDP 175
Query: 122 LGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G + D YTA GSG P+A+ +LE+ Y ++L + A+++A AVK+A RD +G+ I
Sbjct: 176 AGSSMSDTYTAQGSGMPYALGVLEQEYSEDLTMADAEQVAAHAVKSASERDTASGN-GIH 234
Query: 182 VVTITKDGM 190
+ IT DG+
Sbjct: 235 ITKITHDGL 243
>gb|AAF46978.1| (AE003460) CG9868 gene product [Drosophila melanogaster]
Length = 315
Score = 103 bits (254), Expect = 2e-21
Identities = 56/172 (32%), Positives = 97/172 (55%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+G + + GVIL AD++A+ + + +RKI+ + D + T AG D R+L
Sbjct: 71 GTTTLGFKYRGGVILCADSRATSGQYIGSQTMRKIVELNDYMLGTLAGGAADCVYWDRVL 130
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R +Q + + MT A ++ NI E K ++ +++ G+ DE P + +D G
Sbjct: 131 AKECRLHQLRYRKRMTVDTAARIICNISTEYKGMGLVMGMMLAGFDDEGPKLIYVDSEGM 190
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ GSG+P+A+ +L+ GYR +L ++A +LA +A+ A ++D Y+G
Sbjct: 191 RSHGQVFSVGSGSPYALGVLDTGYRYDLSDQEAYDLARRAIYHATSKDAYSG 242
>gi|4506193 proteasome (prosome, macropain) subunit, beta type, 1 [Homo
sapiens] >gi|130853|sp|P20618|PRC5_HUMAN PROTEASOME
COMPONENT C5 (MACROPAIN SUBUNIT C5) (PROTEASOME GAMMA
CHAIN) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C5)
>gi|67732|pir||SNHUC5 multicatalytic endopeptidase
complex (EC 3.4.99.46) beta chain C5 - human
>gi|220026|dbj|BAA00658.1| (D00761) proteasome subunit
C5 [Homo sapiens] >gi|3790135|emb|CAA20287.1| (AL031259)
dJ191N21.3 (proteasome subunit HC5) [Homo sapiens]
Length = 241
Score = 100 bits (246), Expect = 1e-20
Identities = 65/203 (32%), Positives = 108/203 (53%), Gaps = 12/203 (5%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T + I +D I+A+DT+ S + T + K +TD+ I +G GD + +I+
Sbjct: 37 GGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKII 96
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
EA + Y+ + + MTT A+A +LS IL ++FPY V IIGG +E + + DP+G
Sbjct: 97 EARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVG 156
Query: 124 GLIFDDYTATGSGTPFAIAILEE--GYRK-------NLGIEKAKELAIKAVKAAGARDVY 174
D + A GS + +L+ G++ L +++A L +A RDVY
Sbjct: 157 SYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVY 216
Query: 175 TGSKKIQVVTITKDGMKEEFVTL 197
TG +++ +TK+G++EE V+L
Sbjct: 217 TGD-ALRICIVTKEGIREETVSL 238
>gi|11419067 proteasome (prosome, macropain) subunit, beta type, 1 [Homo
sapiens]
Length = 241
Score = 100 bits (246), Expect = 1e-20
Identities = 65/203 (32%), Positives = 108/203 (53%), Gaps = 12/203 (5%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T + I +D I+A+DT+ S + T + K +TD+ I +G GD + +I+
Sbjct: 37 GGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKII 96
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
EA + Y+ + + MTT A+A +LS IL ++FPY V IIGG +E + + DP+G
Sbjct: 97 EARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVG 156
Query: 124 GLIFDDYTATGSGTPFAIAILEE--GYRK-------NLGIEKAKELAIKAVKAAGARDVY 174
D + A GS + +L+ G++ L +++A L +A RDVY
Sbjct: 157 SYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVY 216
Query: 175 TGSKKIQVVTITKDGMKEEFVTL 197
TG +++ +TK+G++EE V+L
Sbjct: 217 TGD-ALRICIVTKEGIREETVSL 238
>dbj|BAA95591.1| (AB035496) 20S proteasome beta 6 subunit [Carassius auratus]
Length = 238
Score = 99.8 bits (245), Expect = 2e-20
Identities = 65/203 (32%), Positives = 112/203 (55%), Gaps = 12/203 (5%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T + + +D ++A+DT+ S + + + + K +TD I +G GD + +I+
Sbjct: 34 GGTVLAVAGEDFALVASDTRLSEGYSIHSRDSPKCYKLTDTTVIGCSGFHGDCLTLTKII 93
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
EA + Y+ + + MT+ A+A +LS IL ++FPY V IIGG +E + + DP+G
Sbjct: 94 EARLKMYKHSNNKSMTSGAIAAMLSTILYGRRFFPYYVYNIIGGLDEEGRGAVYSFDPVG 153
Query: 124 GLIFDDYTATGSGTPFAIAILEE--GYRKNLGIEK---AKELAIKAVK----AAGARDVY 174
D Y A GS + +L+ G++ +E+ ++E A++ VK +A RDVY
Sbjct: 154 SYQRDTYKAGGSASAMLQPLLDNQIGFKNMENVEQVPLSQEKAVQLVKDVFISAAERDVY 213
Query: 175 TGSKKIQVVTITKDGMKEEFVTL 197
TG +++ ITK+G++EE V L
Sbjct: 214 TGD-ALKICIITKEGIREEIVPL 235
>dbj|BAA95592.1| (AB035497) 20S proteasome beta 6 subunit [Carassius auratus]
Length = 237
Score = 99.8 bits (245), Expect = 2e-20
Identities = 65/203 (32%), Positives = 112/203 (55%), Gaps = 12/203 (5%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T + + +D ++A+DT+ S + + + + K +TD I +G GD + +I+
Sbjct: 33 GGTVLAVAGEDFALVASDTRLSEGYSIHSRDSPKCYKLTDTTVIGCSGFHGDCLTLTKII 92
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
EA + Y+ + + MT+ A+A +LS IL ++FPY V IIGG +E + + DP+G
Sbjct: 93 EARLKMYKHSNNKSMTSGAIAAMLSTILYGRRFFPYYVYNIIGGLDEEGRGAVYSFDPVG 152
Query: 124 GLIFDDYTATGSGTPFAIAILEE--GYRKNLGIEK---AKELAIKAVK----AAGARDVY 174
D Y A GS + +L+ G++ +E+ ++E A++ VK +A RDVY
Sbjct: 153 SYQRDTYKAGGSASAMLQPLLDNQIGFKNMENVEQVPLSQEKAVQLVKDVFISAAERDVY 212
Query: 175 TGSKKIQVVTITKDGMKEEFVTL 197
TG +++ ITK+G++EE V L
Sbjct: 213 TGD-ALKICIITKEGIREEIVPL 234
>gi|7242197 proteasome (prosome, macropain) subunit, beta type 1 [Mus musculus]
>gi|2499837|sp|O09061|PRC5_MOUSE PROTEASOME COMPONENT C5
(MACROPAIN SUBUNIT C5) (PROTEASOME GAMMA CHAIN)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C5)
>gi|1165122|emb|CAA56701.1| (X80686) component C5 of
proteasome [Mus musculus] >gi|1698584|gb|AAB37251.1|
(U60824) proteasome beta-subunit C5 [Mus musculus]
Length = 240
Score = 98.7 bits (242), Expect = 4e-20
Identities = 66/203 (32%), Positives = 109/203 (53%), Gaps = 12/203 (5%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T + I +D I+A+DT+ S + T + K +TD+ I +G GD + +I+
Sbjct: 36 GGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKII 95
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
EA + Y+ + + MTT A+A +LS IL ++FPY V IIGG +E + + DP+G
Sbjct: 96 EARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVG 155
Query: 124 GLIFDDYTATGSGTPFAIAILEE--GYRKNLGIEKAK---ELAIKAVK----AAGARDVY 174
D + A GS + +L+ G++ +E + A++ VK +A RDVY
Sbjct: 156 SYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVY 215
Query: 175 TGSKKIQVVTITKDGMKEEFVTL 197
TG +++ +TK+G++EE V L
Sbjct: 216 TGD-ALRICIVTKEGIREETVPL 237
>emb|CAA56702.1| (X80686) component C5 of proteasome [Mus musculus]
Length = 225
Score = 98.7 bits (242), Expect = 4e-20
Identities = 66/203 (32%), Positives = 109/203 (53%), Gaps = 12/203 (5%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T + I +D I+A+DT+ S + T + K +TD+ I +G GD + +I+
Sbjct: 21 GGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKII 80
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
EA + Y+ + + MTT A+A +LS IL ++FPY V IIGG +E + + DP+G
Sbjct: 81 EARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVG 140
Query: 124 GLIFDDYTATGSGTPFAIAILEE--GYRKNLGIEKAK---ELAIKAVK----AAGARDVY 174
D + A GS + +L+ G++ +E + A++ VK +A RDVY
Sbjct: 141 SYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVY 200
Query: 175 TGSKKIQVVTITKDGMKEEFVTL 197
TG +++ +TK+G++EE V L
Sbjct: 201 TGD-ALRICIVTKEGIREETVPL 222
>sp|P18421|PRC5_RAT PROTEASOME COMPONENT C5 (MACROPAIN SUBUNIT C5) (PROTEASOME GAMMA
CHAIN) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C5)
>gi|112213|pir||S09696 multicatalytic endopeptidase
complex (EC 3.4.99.46) chain C5 - rat
>gi|56998|emb|CAA36987.1| (X52783) proteasome subunit
RC5 [Rattus norvegicus]
Length = 240
Score = 95.6 bits (234), Expect = 4e-19
Identities = 65/203 (32%), Positives = 108/203 (53%), Gaps = 12/203 (5%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T + I +D I+A+DT+ S + T + K +TD+ I +G GD + +I+
Sbjct: 36 GGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKII 95
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
EA + Y+ + + MTT A+A +LS IL ++FPY V II G +E + + DP+G
Sbjct: 96 EARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPVG 155
Query: 124 GLIFDDYTATGSGTPFAIAILEE--GYRKNLGIEKAK---ELAIKAVK----AAGARDVY 174
D + A GS + +L+ G++ +E + A++ VK +A RDVY
Sbjct: 156 SYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVY 215
Query: 175 TGSKKIQVVTITKDGMKEEFVTL 197
TG +++ +TK+G++EE V L
Sbjct: 216 TGD-ALRICIVTKEGIREETVPL 237
>pir||S21126 multicatalytic endopeptidase complex (EC 3.4.99.46) chain RC1 - rat
>gi|220881|dbj|BAA01572.1| (D10729) proteasome subunit
RC1 [Rattus sp.]
Length = 208
Score = 93.6 bits (229), Expect = 1e-18
Identities = 57/185 (30%), Positives = 99/185 (52%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++AS + T+ + K+I I + T +G D Q R+L
Sbjct: 4 GTTTLAFKFQHGVIVAVDSRASAGSYIATIRVNKVIEINPYLLGTMSGCAADCQYWERLL 63
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 64 AKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 123
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
+ +TGSG +A +++ GYR++L E+A +LA +A+ A RD Y+G + +
Sbjct: 124 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLARRAIVYATHRDSYSGG-VVNMYH 182
Query: 185 ITKDG 189
+ KDG
Sbjct: 183 MKKDG 187
>sp|P28064|PRCY_RAT PROTEASOME COMPONENT C13 PRECURSOR (MACROPAIN SUBUNIT C13)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C13) (C1)
Length = 271
Score = 93.6 bits (229), Expect = 1e-18
Identities = 57/185 (30%), Positives = 99/185 (52%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++AS + T+ + K+I I + T +G D Q R+L
Sbjct: 67 GTTTLAFKFQHGVIVAVDSRASAGSYIATIRVNKVIEINPYLLGTMSGCAADCQYWERLL 126
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 127 AKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 186
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
+ +TGSG +A +++ GYR++L E+A +LA +A+ A RD Y+G + +
Sbjct: 187 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLARRAIVYATHRDSYSGG-VVNMYH 245
Query: 185 ITKDG 189
+ KDG
Sbjct: 246 MKKDG 250
>sp|O24361|PRCE_SPIOL PROTEASOME EPSILON CHAIN PRECURSOR (MACROPAIN EPSILON CHAIN)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX EPSILON CHAIN)
>gi|7435872|pir||T09132 26S proteasome beta chain -
spinach >gi|2285800|dbj|BAA21650.1| (D78172) 26S
proteasome beta subunit [Spinacia oleracea]
Length = 272
Score = 92.1 bits (225), Expect = 4e-18
Identities = 61/189 (32%), Positives = 102/189 (53%), Gaps = 4/189 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ K GV++AAD++AS+ + + +++KII I + T AG D Q R L
Sbjct: 55 GTTTLAFIFKHGVMVAADSRASMGGYISSQSVKKIIEINPYMLGTMAGGAADCQFWHRNL 114
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
+ R ++ R ++ + LL+NIL + V +I G+ DE P + +D G
Sbjct: 115 GIKCRLHELANKRRISVTGASKLLANILYNYRGMGLSVGTMIAGW-DETGPGLYYVDSEG 173
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
G + + GSG+P+A +L+ GY+ ++ +E+A ELA +A+ A RD +G + V
Sbjct: 174 GRLKGMRFSVGSGSPYAYGVLDNGYKYDMTVEEASELARRAIYHATYRDGASGG-VVSVY 232
Query: 184 TITKDGMKE 192
+ DG K+
Sbjct: 233 HVGPDGWKK 241
>sp|Q60177|PRCA_METJA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) (20S PROTEASOME ALPHA SUBUNIT)
>gi|2118152|pir||G64373 proteasome alpha subunit homolog
- Methanococcus jannaschii >gi|1591299|gb|AAB98581.1|
(U67507) proteasome, subunit alpha (psmA) [Methanococcus
jannaschii]
Length = 261
Score = 92.1 bits (225), Expect = 4e-18
Identities = 58/187 (31%), Positives = 99/187 (52%), Gaps = 7/187 (3%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
+ GTT +GI KDGV+LA D + + +V+ +I KI I D +A T+G V D +++
Sbjct: 33 RRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLID 91
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGY-VDEPTIAN 118
EA+ Y+ T+G ++ +A + +I P+ V ++I G +E +
Sbjct: 92 RARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFE 151
Query: 119 LDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
DP G LI TA GSG P + +LE+ YR ++ +++ ELAI A+ A D+ +
Sbjct: 152 TDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKAN-EDIKPENV 210
Query: 179 KIQVVTI 185
+ ++T+
Sbjct: 211 DVCIITV 217
>gb|AAD22390.1|AF059493_1 (AF059493) proteasome subunit LMP7 [Sus scrofa]
Length = 260
Score = 91.7 bits (224), Expect = 6e-18
Identities = 54/172 (31%), Positives = 93/172 (53%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++AS + TL + K+I I + T +G D Q R+L
Sbjct: 56 GTTTLAFKFQHGVIVAVDSRASAGSYIATLRVNKVIEINPYLLGTMSGCAADCQYWERLL 115
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 116 AKECRLYYLRNGERISVSAASKLLSNMMYQYRGMGLSMGSMICGWDKKGPGLYYVDENGT 175
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + +TGSG +A +++ G+R +L IE+A +L +A+ A RD Y+G
Sbjct: 176 RLSGNMFSTGSGNTYAYGVMDSGHRYDLSIEEAYDLGRRAIVHATHRDSYSG 227
>dbj|BAB02194.1| (AP001298) proteasome epsilon chain precursor [Arabidopsis
thaliana]
Length = 273
Score = 91.7 bits (224), Expect = 6e-18
Identities = 56/173 (32%), Positives = 97/173 (55%), Gaps = 3/173 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ K+GV++AAD++AS+ + + +++KII I + T AG D Q R L
Sbjct: 57 GTTTLAFIFKEGVMVAADSRASMGGYISSQSVKKIIEINPYMLGTMAGGAADCQFWHRNL 116
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
+ R ++ R ++ + LL+N+L + V +I G+ DE P + +D G
Sbjct: 117 GIKCRLHELANKRRISVSGASKLLANMLYSYRGMGLSVGTMIAGW-DETGPGLYYVDNEG 175
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
G + D + GSG+P+A +L+ GY+ ++ +E+A ELA +++ A RD +G
Sbjct: 176 GRLKGDRFSVGSGSPYAYGVLDSGYKFDMSVEEASELARRSIYHATFRDGASG 228
>gb|AAC97957.1| (AF104214) proteasome beta 5 subunit [Trypanosoma cruzi]
Length = 241
Score = 90.9 bits (222), Expect = 1e-17
Identities = 52/177 (29%), Positives = 96/177 (53%), Gaps = 1/177 (0%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
++ K GTTT+G G+ILA D++AS + + + K++ I + + T AG D Q
Sbjct: 35 LDMKKGTTTLGFHFDGGIILAVDSRASSGQYISSQTVMKVLEINEYLLGTMAGGAADCQY 94
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVD-EPTIANL 119
R+L E R ++ ++ A + +L+NI + + + ++ G+ P++ +
Sbjct: 95 WERVLGMECRLWELRNNCRISVAAASKILANITYSYRNYGLSMGTMVAGWDQFGPSLYYV 154
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
D G + + + GSG+ +A +L++GYRKNL +E+A ELA +++ A RD +G
Sbjct: 155 DDKGTRVKHELFSVGSGSIYAYGVLDQGYRKNLTVEEACELARRSIFHATYRDGASG 211
>gi|6325360 proteasome subunit; Pre2p [Saccharomyces cerevisiae]
>gi|730375|sp|P30656|PRCE_YEAST PROTEASOME COMPONENT
PRE2 PRECURSOR (MACROPAIN SUBUNIT PRE2) (PROTEINASE YSCE
SUBUNIT PRE2) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT PRE2) >gi|422174|pir||A45411 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain PRE2
precursor - yeast (Saccharomyces cerevisiae)
>gi|4221|emb|CAA48628.1| (X68662) proteasome Pre2
subunit [Saccharomyces cerevisiae]
>gi|914974|gb|AAB68073.1| (U32445) Proteasome component
Pre2 (Swiss Prot. accession number P30656)
[Saccharomyces cerevisiae] >gi|1041975|gb|AAB34630.1|
Doa3, PRG1, PRE2=beta-type proteasome subunit LMP7
homolog/Hs-X homolog [Saccharomyces cerevisiae, Peptide,
287 aa] >gi|742352|prf||2009376C proteasome:SUBUNIT=Pre2
[Saccharomyces cerevisiae]
Length = 287
Score = 90.9 bits (222), Expect = 1e-17
Identities = 55/186 (29%), Positives = 97/186 (51%), Gaps = 3/186 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ R + G+I+A D++A+ + V + ++K+I I + T AG D Q L
Sbjct: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYV--DEPTIANLDPLG 123
++ R ++ ++ A + +LSN++ + K + +I GY + PTI +D G
Sbjct: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ D GSG FA +L+ Y+ +L +E A L +++ AA RD Y+G + +
Sbjct: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG-SVNLY 253
Query: 184 TITKDG 189
+T+DG
Sbjct: 254 HVTEDG 259
>gi|4758970 proteasome (prosome, macropain) subunit, beta type, 8 (large
multifunctional protease 7); Proteasome subunit, beta
type, 8 (large multifunctional protease-7) [Homo
sapiens] >gi|11417920|ref|XP_004223.1| proteasome
(prosome, macropain) subunit, beta type, 8 (large
multifunctional protease 7) [Homo sapiens]
>gi|1082738|pir||A44324 proteasome chain LMP7 precursor,
splice form E1 - human >gi|34637|emb|CAA47026.1|
(X66401) proteasome-related [Homo sapiens]
>gi|36057|emb|CAA44482.1| (X62598) RING10 [Homo sapiens]
>gi|38481|emb|CAA78705.1| (Z14982) proteasome subunit
LMP7 [Homo sapiens] >gi|1054746|emb|CAA60786.1| (X87344)
alternative first exon (1a) [Homo sapiens]
>gi|228159|prf||1717394A RING10 gene [Homo sapiens]
Length = 272
Score = 90.9 bits (222), Expect = 1e-17
Identities = 54/172 (31%), Positives = 90/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI A D++AS + L + K+I I + T +G D Q R+L
Sbjct: 68 GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLL 127
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 128 AKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGT 187
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + +TGSG +A +++ GYR NL E+A +L +A+ A RD Y+G
Sbjct: 188 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSG 239
>pir||C44324 proteasome chain LMP7 precursor, splice form E1 - human
>gi|38482|emb|CAA78706.1| (Z14982) proteasome subunit
LMP7 [Homo sapiens] >gi|1054747|emb|CAA60787.1| (X87344)
alternative first exon (1b) [Homo sapiens]
Length = 276
Score = 90.9 bits (222), Expect = 1e-17
Identities = 54/172 (31%), Positives = 90/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI A D++AS + L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + +TGSG +A +++ GYR NL E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSG 243
>gb|AAA34906.1| (M96667) proteosome-related protein [Saccharomyces cerevisiae]
Length = 288
Score = 90.9 bits (222), Expect = 1e-17
Identities = 55/186 (29%), Positives = 97/186 (51%), Gaps = 3/186 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ R + G+I+A D++A+ + V + ++K+I I + T AG D Q L
Sbjct: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYV--DEPTIANLDPLG 123
++ R ++ ++ A + +LSN++ + K + +I GY + PTI +D G
Sbjct: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ D GSG FA +L+ Y+ +L +E A L +++ AA RD Y+G + +
Sbjct: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG-SVNLY 253
Query: 184 TITKDG 189
+T+DG
Sbjct: 254 HVTEDG 259
>pir||G01564 proteasome chain LMP7 precursor, splice form E2 - human
>gi|596140|gb|AAA56777.1| (U17496) proteasome subunit
LMP7 [Homo sapiens]
Length = 276
Score = 90.9 bits (222), Expect = 1e-17
Identities = 54/172 (31%), Positives = 90/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI A D++AS + L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + +TGSG +A +++ GYR NL E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSG 243
>gb|AAA56778.1| (U17497) proteasome subunit LMP7 [Homo sapiens]
Length = 276
Score = 90.9 bits (222), Expect = 1e-17
Identities = 54/172 (31%), Positives = 90/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI A D++AS + L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + +TGSG +A +++ GYR NL E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSG 243
>sp|P28062|PRCY_HUMAN PROTEASOME COMPONENT C13 PRECURSOR (MACROPAIN SUBUNIT C13)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C13)
Length = 276
Score = 90.9 bits (222), Expect = 1e-17
Identities = 54/172 (31%), Positives = 90/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI A D++AS + L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + +TGSG +A +++ GYR NL E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSG 243
>sp|O23717|PRCE_ARATH PROTEASOME EPSILON CHAIN PRECURSOR (MACROPAIN EPSILON CHAIN)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX EPSILON CHAIN)
>gi|2511596|emb|CAA74029.1| (Y13695) multicatalytic
endopeptidase complex, proteasome precursor, beta
subunit [Arabidopsis thaliana]
>gi|3421117|gb|AAC32072.1| (AF043536) 20S proteasome
beta subunit PBE1 [Arabidopsis thaliana]
>gi|4850389|gb|AAD31059.1|AC007357_8 (AC007357)
Identical to gb|Y13695 multicatalytic endopeptidase
complex, proteasome precursor, beta subunit (prce) from
Arabidopsis thaliana. ESTs gb|Y09360, gb|F13852,
gb|T20555, gb|T44620, gb|AI099779 and gb|AA586183 come
from this gene
Length = 274
Score = 90.9 bits (222), Expect = 1e-17
Identities = 56/173 (32%), Positives = 96/173 (55%), Gaps = 3/173 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ K GV++AAD++AS+ + + +++KII I + T AG D Q R L
Sbjct: 57 GTTTLAFIFKGGVMVAADSRASMGGYISSQSVKKIIEINPYMLGTMAGGAADCQFWHRNL 116
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
+ R ++ R ++ + LL+N+L + V +I G+ DE P + +D G
Sbjct: 117 GIKCRLHELANKRRISVSGASKLLANMLYSYRGMGLSVGTMIAGW-DETGPGLYYVDNEG 175
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
G + D + GSG+P+A +L+ GY+ ++ +E+A ELA +++ A RD +G
Sbjct: 176 GRLKGDRFSVGSGSPYAYGVLDSGYKYDMSVEEASELARRSIYHATFRDGASG 228
>dbj|BAA28276.1| (AB014058) beta 6 subunit of 20S proteasome [Oryza sativa]
Length = 221
Score = 90.9 bits (222), Expect = 1e-17
Identities = 61/207 (29%), Positives = 101/207 (48%), Gaps = 16/207 (7%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T V I D ++AADT+ S+ + + T + KI + D+ A+ ++G GD++ + + L
Sbjct: 13 GGTCVAIAGADYCVVAADTRLSVGYNILTRDHSKICELADKCALASSGFQGDIKALHKNL 72
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
A YQ + M+ AMA LLSN L ++FPY ++GG E + D +G
Sbjct: 73 AARELLYQHQHNKRMSCPAMAQLLSNTLYYKRFFPYYAFNVLGGLDSEGKGCVFTYDAVG 132
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRK-------------NLGIEKAKELAIKAVKAAGA 170
Y+A G+G+ + +L+ + L +A +L +A
Sbjct: 133 SYERTGYSAQGTGSALIMPVLDNQLKSPSPLLLPARDAVTPLSETEAVDLVKDVFASATE 192
Query: 171 RDVYTGSKKIQVVTITKDGMKEEFVTL 197
RD+YTG K+++V I K G K E++ L
Sbjct: 193 RDIYTGD-KLEIVVINKAGTKREYIDL 218
>pir||I51536 XeLMPa.aa - African clawed frog >gi|971307|dbj|BAA07945.1| (D44540)
low molecular mass protein-7 (LMP-7) homolog [Xenopus
laevis]
Length = 271
Score = 90.5 bits (221), Expect = 1e-17
Identities = 54/172 (31%), Positives = 91/172 (52%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++AS + T+ K+I I + T +GS D Q R+L
Sbjct: 66 GTTTLAFKFQHGVIVAVDSRASAGSYISTIKFNKVIEINPYLLGTMSGSAADCQYWERLL 125
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R YQ ++ A + L+ N++ + + V +I G+ + P + +D G
Sbjct: 126 AKECRLYQLRNNSRISVSAASKLMCNMMLQYRGTGLSVGSMICGWDKKGPGLYYVDDNGT 185
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ D +TGSG +A +++ GYR +L E+A +L +A+ A RD Y+G
Sbjct: 186 RLCGDIFSTGSGNSYAYGVMDSGYRFDLTPEEAYDLGRRAISYATHRDAYSG 237
>dbj|BAA10932.1| (D64055) LMPX of lamprey [Petromyzon marinus]
Length = 273
Score = 89.3 bits (218), Expect = 3e-17
Identities = 51/172 (29%), Positives = 93/172 (53%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + + ++K+I I + T AG D R+L
Sbjct: 70 GTTTLAFKFQHGVIVAVDSRATAGSYIASQTVKKVIEINPYLLGTMAGGAADCMYWERVL 129
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ + P + +D G
Sbjct: 130 AKQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKKGPGLYYVDDEGM 189
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ A GSG+P+A +L+ GYR++L E+A +L +A+ +A RD Y+G
Sbjct: 190 RLPGSMFAVGSGSPYAFGVLDSGYREDLSKEEAYDLGRRAIASATHRDAYSG 241
>dbj|BAA19767.1| (D89725) LMP7 [Oryzias latipes]
Length = 225
Score = 89.3 bits (218), Expect = 3e-17
Identities = 57/185 (30%), Positives = 96/185 (51%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + K GVI+A D++AS + T K+I I + T +GS D + R+L
Sbjct: 21 GTTTLSFKFKHGVIVAVDSRASTGSYIATCEYNKVIEINPYLLGTMSGSAADCKYWERLL 80
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y+ ++ A + LL N++ + V +I G+ E P I +D G
Sbjct: 81 AKECRLYRLRNNHRISVAAASKLLCNMMLGYRGMGLSVGSMICGWDKEGPGIYYVDDNGN 140
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
+ +TGSG+ +A +L+ GY++++ +E+A EL + + A RD Y+G + +
Sbjct: 141 RLSGRMFSTGSGSNYAYGVLDSGYKEDMTVEEAYELGRRGIVHATHRDSYSGG-VVNMYH 199
Query: 185 ITKDG 189
I +DG
Sbjct: 200 IQEDG 204
>pir||T40487 proteasome component precursor - fission yeast
(Schizosaccharomyces pombe) >gi|2832891|emb|CAA16832.1|
(AL021730) proteasome component precursor
[Schizosaccharomyces pombe]
Length = 226
Score = 89.3 bits (218), Expect = 3e-17
Identities = 63/197 (31%), Positives = 99/197 (49%), Gaps = 6/197 (3%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
+ GTT +R KDGVILAAD++ ++ + K+ +TD I +GS D Q +A
Sbjct: 22 RMGTTITALRYKDGVILAADSRTTMGAYIANRVTDKLTQLTDNIWCCRSGSAADTQTVAD 81
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANL--DP 121
+L+ Y+ +G + A L S + +NK +I+ GY DE T ++ P
Sbjct: 82 LLKYYLSMYRIQFGHDPSVHTAATLASEMCYQNKNM-LSAGLIVAGY-DEKTGGDVYSIP 139
Query: 122 LGGLIFDDYTAT-GSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKI 180
LGG + A GSG+ F + +R+N+ E+A E AV A RD +G I
Sbjct: 140 LGGSLHKQPLAIGGSGSAFIYGFCDANFRENMTQEEAVEFLKNAVALAMERDGSSGG-TI 198
Query: 181 QVVTITKDGMKEEFVTL 197
++V + KDGM+ +F +
Sbjct: 199 RMVILNKDGMERKFFAI 215
>dbj|BAA96838.1| (AB026567) beta 5 subunit of 20S proteasome [Oryza sativa]
Length = 277
Score = 89.3 bits (218), Expect = 3e-17
Identities = 57/177 (32%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
+ K GTTT+ GVI+AAD++AS+ + + +RKII I + T AG D Q
Sbjct: 55 LKHKKGTTTLAFIFDKGVIVAADSRASMGGYISSQTVRKIIEINPYMLGTMAGGAADCQF 114
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANL 119
R L + R ++ R ++ + LL+NIL + + +I G+ ++ P + +
Sbjct: 115 WHRNLGIKCRLHELANKRRISIAGASKLLANILYSYRGMGLSIGTMIAGWDEKGPGLYYV 174
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
D G + + GSG+ +A IL+EGYR + +E+A ELA +A+ A RD +G
Sbjct: 175 DSEGARLMGSRFSVGSGSLYAYGILDEGYRYVMPVEEAAELARRAIYQATFRDGASG 231
>gi|4506191 proteasome (prosome, macropain) subunit, beta type, 10; Proteosome
subunit MECL1 [Homo sapiens]
>gi|730376|sp|P40306|PRCF_HUMAN PROTEASOME COMPONENT
MECL-1 PRECURSOR (MACROPAIN SUBUNIT MECL-1)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT MECL-1)
>gi|2136008|pir||I38135 multicatalytic endopeptidase
complex (EC 3.4.99.46) beta chain MECL-1 - human
>gi|406227|emb|CAA50709.1| (X71874) proteasome-like
subunit MECL-1 [Homo sapiens]
>gi|2765348|emb|CAA73982.1| (Y13640) proteasome subunit
MECl-1 [Homo sapiens]
Length = 273
Score = 88.5 bits (216), Expect = 5e-17
Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 1/189 (0%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT G+ +DGVIL ADT+A+ D +V + KI I +I AG D +M
Sbjct: 36 RKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTT 95
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
R++ ++ + + GR + +L L + I+ G + P + + P
Sbjct: 96 RMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPH 155
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G +TA GSG A+A+LE+ ++ N+ +E A+ L ++AV A D+ +G +
Sbjct: 156 GSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGG-NVDA 214
Query: 183 VTITKDGMK 191
ITK G K
Sbjct: 215 CVITKTGAK 223
>gb|AAB86994.1| (U77784) Lmp10 proteasome subunit [Mus musculus]
>gi|2252792|gb|AAB87637.1| (U77785) Lmp10 proteasome
subunit; MECL1 [Mus musculus]
>gi|2547057|dbj|BAA22855.1| (D85561) proteasome subunit
MECL1 [Mus musculus] >gi|2547059|dbj|BAA22856.1|
(D85562) proteasome subunit MECL1 [Mus musculus]
Length = 273
Score = 88.5 bits (216), Expect = 5e-17
Identities = 57/189 (30%), Positives = 94/189 (49%), Gaps = 1/189 (0%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT G+ +DGVIL ADT+A+ D +V + KI I +I AG D +M
Sbjct: 36 RKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTT 95
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
R+ ++ + + GR + +L L + ++ G ++ P + + P
Sbjct: 96 RMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPH 155
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G +TA GSG A+A+LE+ ++ N+ +E A+EL ++A+ A D+ +G +
Sbjct: 156 GSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGG-NVDA 214
Query: 183 VTITKDGMK 191
IT G K
Sbjct: 215 CVITAGGAK 223
>pdb|1G0U|K Chain K, A Gated Channel Into The Proteasome Core Particle
>gi|11514016|pdb|1G0U|Y Chain Y, A Gated Channel Into
The Proteasome Core Particle
Length = 212
Score = 88.5 bits (216), Expect = 5e-17
Identities = 54/185 (29%), Positives = 96/185 (51%), Gaps = 3/185 (1%)
Query: 7 TTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILE 66
TTT+ R + G+I+A D++A+ + V + ++K+I I + T AG D Q L
Sbjct: 1 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 60
Query: 67 AEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYV--DEPTIANLDPLGG 124
++ R ++ ++ A + +LSN++ + K + +I GY + PTI +D G
Sbjct: 61 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 120
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
+ D GSG FA +L+ Y+ +L +E A L +++ AA RD Y+G + +
Sbjct: 121 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG-SVNLYH 179
Query: 185 ITKDG 189
+T+DG
Sbjct: 180 VTEDG 184
>sp|P28063|PRCY_MOUSE PROTEASOME COMPONENT C13 PRECURSOR (MACROPAIN SUBUNIT C13)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C13)
>gi|2137569|pir||I54513 multicatalytic endopeptidase
complex (EC 3.4.99.46) type beta chain MC13 - mouse
>gi|494969|gb|AAB46392.1| (L11145) lmp7 [Mus musculus]
>gi|582390|emb|CAA45779.1| (X64449) proteasome subunit
MC13 [Mus musculus] >gi|972982|gb|AAA75033.1| (U22031)
20S proteasome subunit Lmp7 [Mus musculus]
>gi|972984|gb|AAA75034.1| (U22032) 20S proteasome
subunit Lmp7 [Mus musculus] >gi|2555193|gb|AAB81532.1|
(AF027865) 20S proteosome subunit lmp7 [Mus musculus]
Length = 276
Score = 88.2 bits (215), Expect = 6e-17
Identities = 52/172 (30%), Positives = 92/172 (53%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + +L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TGSG +A +++ GYR++L E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSG 243
>emb|CAA45780.1| (X64449) proteasome subunit MC13 [Mus musculus]
Length = 208
Score = 88.2 bits (215), Expect = 6e-17
Identities = 52/172 (30%), Positives = 92/172 (53%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + +L + K+I I + T +G D Q R+L
Sbjct: 4 GTTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLL 63
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 64 AKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 123
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TGSG +A +++ GYR++L E+A +L +A+ A RD Y+G
Sbjct: 124 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSG 175
>gb|AAA75035.1| (U22033) 20S proteasome subunit Lmp7 [Mus musculus]
>gi|972988|gb|AAA75036.1| (U22034) 20S proteasome
subunit Lmp7 [Mus musculus]
Length = 276
Score = 88.2 bits (215), Expect = 6e-17
Identities = 52/172 (30%), Positives = 92/172 (53%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + +L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TGSG +A +++ GYR++L E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSG 243
>gb|AAA75037.1| (U22035) 20S proteasome subunit Lmp7 [Mus musculus]
Length = 276
Score = 88.2 bits (215), Expect = 6e-17
Identities = 52/172 (30%), Positives = 92/172 (53%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + +L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TGSG +A +++ GYR++L E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSG 243
>gi|7305417 proteasome (prosomome, macropain) subunit, beta type 10 [Mus
musculus] >gi|2062109|emb|CAA71825.1| (Y10875)
proteasome subnuit MECL-1 [Mus musculus]
Length = 273
Score = 88.2 bits (215), Expect = 6e-17
Identities = 57/189 (30%), Positives = 94/189 (49%), Gaps = 1/189 (0%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT G+ +DGVIL ADT+A+ D +V + KI I +I AG D +M
Sbjct: 36 RKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTT 95
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
R+ ++ + + GR + +L L + ++ G ++ P + + P
Sbjct: 96 RMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPH 155
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G +TA GSG A+A+LE+ ++ N+ +E A+EL ++A+ A D+ +G +
Sbjct: 156 GSYSRLPFTALGSGQGAAVALLEDRFQPNMTLELAQELLVEAITAGILSDLGSGG-NVDA 214
Query: 183 VTITKDGMK 191
IT G K
Sbjct: 215 CVITAGGAK 223
>gi|6755208 proteosome (prosome, macropain) subunit, beta type 8 (large
multifunctional protease 7); large multifunctional
protease 7 [Mus musculus] >gi|6249512|emb|CAB60065.1|
(Z21847) lmp7 [Mus musculus]
Length = 275
Score = 88.2 bits (215), Expect = 6e-17
Identities = 52/172 (30%), Positives = 92/172 (53%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + +L + K+I I + T +G D Q R+L
Sbjct: 72 GTTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLL 131
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y G ++ A + LLSN++ + + + +I G+ + P + +D G
Sbjct: 132 AKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 191
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TGSG +A +++ GYR++L E+A +L +A+ A RD Y+G
Sbjct: 192 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSG 243
>gb|AAF37285.1|AF226674_1 (AF226674) 20S proteasome beta 5 subunit [Trypanosoma brucei]
Length = 250
Score = 88.2 bits (215), Expect = 6e-17
Identities = 50/177 (28%), Positives = 96/177 (53%), Gaps = 1/177 (0%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
++ K GTTT+G G+I+A D++AS + + + K++ I + + T AG D Q
Sbjct: 41 LDMKKGTTTLGFHFDGGIIIAVDSRASSGQYISSQTVMKVLEINEYLLGTMAGGAADCQY 100
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVD-EPTIANL 119
R+L E R ++ ++ A + +L+NI + + + ++ G+ P++ +
Sbjct: 101 WERVLGMECRLWELRNNCRISVAAASKILANITYQYRNHGLSMGTMVAGWDQFGPSLYYV 160
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
D G + + + GSG+ +A +L++GYRKNL +E+A +LA +++ A RD +G
Sbjct: 161 DDKGTRVKHEIFSVGSGSIYAYGVLDQGYRKNLTVEEACDLARRSIFHATYRDGASG 217
>emb|CAC08538.1| (AJ132959) proteasome PRCE (beta-5) subunit precursor [Trypanosoma
brucei]
Length = 310
Score = 88.2 bits (215), Expect = 6e-17
Identities = 50/177 (28%), Positives = 96/177 (53%), Gaps = 1/177 (0%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
++ K GTTT+G G+I+A D++AS + + + K++ I + + T AG D Q
Sbjct: 101 LDMKKGTTTLGFHFDGGIIIAVDSRASSGQYISSQTVMKVLEINEYLLGTMAGGAADCQY 160
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVD-EPTIANL 119
R+L E R ++ ++ A + +L+NI + + + ++ G+ P++ +
Sbjct: 161 WERVLGMECRLWELRNNCRISVAAASKILANITYQYRNHGLSMGTMVAGWDQFGPSLYYV 220
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
D G + + + GSG+ +A +L++GYRKNL +E+A +LA +++ A RD +G
Sbjct: 221 DDKGTRVKHEIFSVGSGSIYAYGVLDQGYRKNLTVEEACDLARRSIFHATYRDGASG 277
>pir||I52906 proteasome subunit MB1 - human (fragment) >gi|786582|gb|AAB33092.1|
(S74378) proteasome subunit MB1=LMP7 homolog [human, JY
T-cells, Peptide Partial, 215 aa] [Homo sapiens]
Length = 215
Score = 87.8 bits (214), Expect = 8e-17
Identities = 53/185 (28%), Positives = 98/185 (52%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+AAD++A+ + + ++K+I I + T AG GD R+L
Sbjct: 11 GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAGDCSFWERLL 70
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 71 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGSMICGWDKRGPGLYYVDSEGN 130
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
I + GSG+ +A +++ GY +L +E+A +LA +A+ A RD Y+G + +
Sbjct: 131 RISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGG-AVNLYH 189
Query: 185 ITKDG 189
+ +DG
Sbjct: 190 VREDG 194
>dbj|BAA10934.1| (D64057) LMP7 [Ginglymostoma cirratum]
Length = 278
Score = 87.8 bits (214), Expect = 8e-17
Identities = 52/172 (30%), Positives = 95/172 (55%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++AS + + +++ K+I I + T +GS D Q R+L
Sbjct: 70 GTTTLAFKFQHGVIVAVDSRASAGNYLASVDANKVIEINPYLLGTMSGSAADCQYWERLL 129
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ + ++ A + LLSN++ E + + +I G+ + P + +D G
Sbjct: 130 AKQCRLYKLRNKQRISVSAASKLLSNMMCEYRGMGLSMGSMICGWDKKGPGLYYVDDNGT 189
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + +TG G +A +++ GYR +L +E+A +L +A+ A RD YTG
Sbjct: 190 RLSGNMFSTGCGNVYAYGVVDSGYRYDLTVEEAYDLGRRAIYHATHRDAYTG 241
>gb|AAF72737.1|AF097521_1 (AF097521) proteasome B type subunit [Cryptosporidium parvum]
Length = 210
Score = 87.8 bits (214), Expect = 8e-17
Identities = 60/193 (31%), Positives = 100/193 (51%), Gaps = 3/193 (1%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
+TGTT V ++ KDG++LAAD + S ++ RKI ITD++ + +GS D Q+I+R
Sbjct: 11 ETGTTIVALKYKDGLVLAADGRTSTGPIIAFRAARKITQITDKVFMCRSGSAADTQIISR 70
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
+ + ++ G +++A++ I +NK II G + PLG
Sbjct: 71 YVRRIVQDHELETGEDTKVKSVASVARLISYQNKEHLLADMIIAGMDPNGEFKVFRIPLG 130
Query: 124 G-LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G LI Y +GSG+ + ++L+ Y + +++ K A V A RD +G I++
Sbjct: 131 GTLIEGSYAISGSGSGYIYSMLDSKYHSEMDLDECKSFARDLVSHAMFRDSSSGG-IIRI 189
Query: 183 VTITKDGMKEEFV 195
+ I K G+ EEFV
Sbjct: 190 IVINKSGV-EEFV 201
>pir||I51537 XeLMPb.aa - African clawed frog >gi|971309|dbj|BAA07954.1| (D44549)
low molecular mass protein-7 (LMP-7) homolog [Xenopus
laevis]
Length = 271
Score = 87.4 bits (213), Expect = 1e-16
Identities = 55/172 (31%), Positives = 90/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + K GVI+A D++AS + +L K+I I + T +GS D Q R+L
Sbjct: 66 GTTTLAFKFKHGVIVAVDSRASAGSYIASLKANKVIEINPYLLGTMSGSAADCQHWERLL 125
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R YQ ++ + + LL N++ + + V +I G+ + P + +D G
Sbjct: 126 AKECRLYQLRNNSRISVSSASKLLCNMMLQYRGSGLSVGSMICGWDKKGPGLYYVDDNGT 185
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ D +TGSG +A +++ GYR +L E+A +L A+ A RD Y+G
Sbjct: 186 RLCGDIFSTGSGNSYAYGVMDSGYRFDLTPEEAYDLGRHAISYATHRDNYSG 237
>pdb|1RYP|L Chain L, Crystal Structure Of The 20s Proteasome From Yeast At 2.4
Angstroms Resolution >gi|3114294|pdb|1RYP|Z Chain Z,
Crystal Structure Of The 20s Proteasome From Yeast At
2.4 Angstroms Resolution
Length = 212
Score = 87.4 bits (213), Expect = 1e-16
Identities = 53/185 (28%), Positives = 96/185 (51%), Gaps = 3/185 (1%)
Query: 7 TTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILE 66
TTT+ R + G+I+A D++A+ + V + ++++I I + T AG D Q L
Sbjct: 1 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKRVIEINPFLLGTMAGGAADCQFWETWLG 60
Query: 67 AEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYV--DEPTIANLDPLGG 124
++ R ++ ++ A + +LSN++ + K + +I GY + PTI +D G
Sbjct: 61 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 120
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
+ D GSG FA +L+ Y+ +L +E A L +++ AA RD Y+G + +
Sbjct: 121 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG-SVNLYH 179
Query: 185 ITKDG 189
+T+DG
Sbjct: 180 VTEDG 184
>pdb|1G65|K Chain K, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513437|pdb|1G65|Y Chain Y, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors
Length = 211
Score = 86.6 bits (211), Expect = 2e-16
Identities = 53/184 (28%), Positives = 95/184 (50%), Gaps = 3/184 (1%)
Query: 8 TTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILEA 67
TT+ R + G+I+A D++A+ + V + ++K+I I + T AG D Q L +
Sbjct: 1 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGS 60
Query: 68 EARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYV--DEPTIANLDPLGGL 125
+ R ++ ++ A + +LSN++ + K + +I GY + PTI +D G
Sbjct: 61 QCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTR 120
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTI 185
+ D GSG FA +L+ Y+ +L +E A L +++ AA RD Y+G + + +
Sbjct: 121 LKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG-SVNLYHV 179
Query: 186 TKDG 189
T+DG
Sbjct: 180 TEDG 183
>gb|AAF26416.1|AF217726_1 (AF217726) 20S proteasome beta5 subunit [Drosophila melanogaster]
Length = 282
Score = 86.6 bits (211), Expect = 2e-16
Identities = 56/190 (29%), Positives = 101/190 (52%), Gaps = 2/190 (1%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
+N GTTT+G + K GV+LA D++A+ + + +++KI+ I + T AG D
Sbjct: 68 INFDHGTTTLGFKFKGGVLLAVDSRATGGSYIGSQSMKKIVEINQFMLGTLAGGAADCVY 127
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANL 119
R+L E R ++ ++ A + +++NI +E K + +++ GY P + +
Sbjct: 128 WDRVLSKECRLHELRNKERISVAAASKIMANIAHEYKGMGLSMGMMLAGYDKRGPGLYYV 187
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
D G + + GSG+ +A +L+ GY +L ++A+EL +A+ A RD Y+G
Sbjct: 188 DSEGSRTPGNLFSVGSGSLYAYGVLDSGYHWDLEDKEAQELGRRAIYHATFRDAYSGG-I 246
Query: 180 IQVVTITKDG 189
I+V I +DG
Sbjct: 247 IRVYHIKEDG 256
>gb|AAF58748.1| (AE003828) Prosbeta5 gene product [Drosophila melanogaster]
Length = 282
Score = 86.6 bits (211), Expect = 2e-16
Identities = 56/190 (29%), Positives = 101/190 (52%), Gaps = 2/190 (1%)
Query: 1 MNRKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQM 60
+N GTTT+G + K GV+LA D++A+ + + +++KI+ I + T AG D
Sbjct: 68 INFDHGTTTLGFKFKGGVLLAVDSRATGGSYIGSQSMKKIVEINQFMLGTLAGGAADCVY 127
Query: 61 IARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANL 119
R+L E R ++ ++ A + +++NI +E K + +++ GY P + +
Sbjct: 128 WDRVLSKECRLHELRNKERISVAAASKIMANIAHEYKGMGLSMGMMLAGYDKRGPGLYYV 187
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
D G + + GSG+ +A +L+ GY +L ++A+EL +A+ A RD Y+G
Sbjct: 188 DSEGSRTPGNLFSVGSGSLYAYGVLDSGYHWDLEDKEAQELGRRAIYHATFRDAYSGG-I 246
Query: 180 IQVVTITKDG 189
I+V I +DG
Sbjct: 247 IRVYHIKEDG 256
>dbj|BAA96834.1| (AB026563) beta 1 subunit of 20S proteasome [Oryza sativa]
Length = 246
Score = 86.6 bits (211), Expect = 2e-16
Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
+ GTT VG+ GV+LAAD++ S V KI +TD + I +GS D Q+I+
Sbjct: 23 RMGTTIVGVCYDGGVVLAADSRTSTGMYVANRASDKITQLTDNVYICRSGSAADTQVISD 82
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
+ + G+P T + ANL+ + +NK I+ G E PLG
Sbjct: 83 YVRYFLHQHTIQLGQPATVKVAANLIRLLAYQNKNMLQAGMIVGGWDKYEGGQIFSVPLG 142
Query: 124 GLIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G I + GSG+ + +L+ +++ + E+A++ +K V A ARD +G ++
Sbjct: 143 GTILRQPFAIGGSGSSYLYGLLDHEWKEGMSQEEAEKFVVKVVSLAIARDGASGG-VVRT 201
Query: 183 VTITKDGMKEEF 194
VTI DG+ +F
Sbjct: 202 VTINADGVSRKF 213
>sp|P28075|PRCE_RAT PROTEASOME EPSILON CHAIN PRECURSOR (MACROPAIN EPSILON CHAIN)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX EPSILON CHAIN)
(PROTEASOME SUBUNIT X) (PROTEASOME CHAIN 6)
>gi|639871|dbj|BAA08204.1| (D45247) proteasome subunit
RCX [Rattus rattus]
Length = 208
Score = 86.2 bits (210), Expect = 2e-16
Identities = 52/185 (28%), Positives = 97/185 (52%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+AAD++A+ + + ++K+I I + T AG D R+L
Sbjct: 4 GTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 63
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 64 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 123
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
I + GSG+ +A +++ GY +L +E+A +LA +A+ A RD Y+G + +
Sbjct: 124 RISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGG-AVNLYH 182
Query: 185 ITKDG 189
+ +DG
Sbjct: 183 VREDG 187
>sp|P28074|PRCE_HUMAN PROTEASOME EPSILON CHAIN PRECURSOR (MACROPAIN EPSILON CHAIN)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX EPSILON CHAIN)
(PROTEASOME SUBUNIT X) (PROTEASOME CHAIN 6) (PROTEASOME
SUBUNIT MB1) >gi|1362908|pir||A54589 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain X - human
>gi|558526|dbj|BAA06097.1| (D29011) proteasome subunit X
[Homo sapiens]
Length = 208
Score = 85.8 bits (209), Expect = 3e-16
Identities = 52/185 (28%), Positives = 97/185 (52%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+AAD++A+ + + ++K+I I + T AG D R+L
Sbjct: 4 GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 63
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 64 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 123
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
I + GSG+ +A +++ GY +L +E+A +LA +A+ A RD Y+G + +
Sbjct: 124 RISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGG-AVNLYH 182
Query: 185 ITKDG 189
+ +DG
Sbjct: 183 VREDG 187
>gi|4506201 proteasome (prosome, macropain) subunit, beta type, 5; Proteasome
subunit, beta type, 5; X [Homo sapiens]
>gi|11437533|ref|XP_007514.1| proteasome (prosome,
macropain) subunit, beta type, 5 [Homo sapiens]
>gi|1262338|emb|CAA64838.1| (X95586) proteasome [Homo
sapiens]
Length = 263
Score = 85.8 bits (209), Expect = 3e-16
Identities = 52/185 (28%), Positives = 97/185 (52%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+AAD++A+ + + ++K+I I + T AG D R+L
Sbjct: 59 GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 178
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
I + GSG+ +A +++ GY +L +E+A +LA +A+ A RD Y+G + +
Sbjct: 179 RISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGG-AVNLYH 237
Query: 185 ITKDG 189
+ +DG
Sbjct: 238 VREDG 242
>pir||S30539 multicatalytic endopeptidase complex (EC 3.4.99.46) chain C1 -
chicken (fragment) >gi|62972|emb|CAA40494.1| (X57210)
proteasome C1 subunit [Gallus gallus]
Length = 204
Score = 85.4 bits (208), Expect = 4e-16
Identities = 50/172 (29%), Positives = 90/172 (52%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + GV++A D++A+ + + ++K+I I + T AG D R+L
Sbjct: 3 GTTTLAFKFAHGVVVAVDSRATAGSYIASQTVQKVIEINPSLLGTMAGGAADCSFWERLL 62
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ P++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 63 ARQCRVYELRNKEPISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGT 122
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
I + A GSG+ +A +L+ G R ++ ++A ELA +A+ A RD Y+G
Sbjct: 123 RIPGEAFAVGSGSSYAYGVLDGGRRPDMATDEALELARRAIFQAARRDAYSG 174
>dbj|BAA10933.1| (D64056) LMP7 of nurse shark [Ginglymostoma cirratum]
Length = 274
Score = 85.4 bits (208), Expect = 4e-16
Identities = 50/172 (29%), Positives = 95/172 (55%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GV++A D++AS + T +K+I I + T +GS D R+L
Sbjct: 70 GTTTLAFKFQHGVMVAVDSRASAGSYISTQMFKKVIEINPYLLGTMSGSAADCVFWERML 129
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ + ++ A + LL+N+++E K + +I G+ ++ P + ++ G
Sbjct: 130 AKQCRIYKLRNKKRISVSAASKLLANMVSEYKGMGLSMGTMICGWDEKGPGLYYVNDGGM 189
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TGSG +A +++ GYR +L +++A +LA +A+ A RD Y+G
Sbjct: 190 RLSGSMFSTGSGCSYAYGVMDSGYRYDLTVKEAYDLAQRAIYHATHRDAYSG 241
>sp|P93395|PRCD_TOBAC PROTEASOME DELTA CHAIN PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX DELTA CHAIN) >gi|7435893|pir||T03985
multicatalytic endopeptidase complex (EC 3.4.99.46)
delta chain - common tobacco >gi|1743356|emb|CAA70699.1|
(Y09505) proteasome delta subunit [Nicotiana tabacum]
Length = 234
Score = 85.4 bits (208), Expect = 4e-16
Identities = 54/191 (28%), Positives = 96/191 (49%), Gaps = 4/191 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTT +G+ GV+L AD++ S V KI +TD + + +GS D Q+++ +
Sbjct: 13 GTTIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQIVSDYV 72
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY--VDEPTIANLDPLG 123
+ G+P T + AN L+ +L+ N +IIGG+ + I + P G
Sbjct: 73 RYFLHQHTIQLGQPATVKVAAN-LTRLLSYNNKDRLQTGMIIGGWDKYEGGKIYGIPPGG 131
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
++ + GSG+ + ++ +++ + E+A++L + AV A ARD +G ++ V
Sbjct: 132 TVLEQPFAIGGSGSSYLYGFFDQAWKEGMTQEEAEKLVVTAVSLAIARDGASGG-VVRTV 190
Query: 184 TITKDGMKEEF 194
TI KDG +F
Sbjct: 191 TINKDGATRKF 201
>sp|P34065|PRCE_CHICK PROTEASOME CHAIN 1 PRECURSOR (MACROPAIN CHAIN 1) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX CHAIN 1)
>gi|1906303|dbj|BAA19471.1| (AB001935) proteasome C1
subunit [Gallus gallus]
Length = 256
Score = 85.4 bits (208), Expect = 4e-16
Identities = 50/172 (29%), Positives = 90/172 (52%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + GV++A D++A+ + + ++K+I I + T AG D R+L
Sbjct: 55 GTTTLAFKFAHGVVVAVDSRATAGSYIASQTVQKVIEINPSLLGTMAGGAADCSFWERLL 114
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ P++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 115 ARQCRVYELRNKEPISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGT 174
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
I + A GSG+ +A +L+ G R ++ ++A ELA +A+ A RD Y+G
Sbjct: 175 RIPGEAFAVGSGSSYAYGVLDGGRRPDMATDEALELARRAIFQAARRDAYSG 226
>pir||T43887 proteasome alpha chain [imported] - Thermococcus sp
>gi|2398843|dbj|BAA22211.1| (AB001084) proteasome alpha
subunit [Thermococcus sp. KS-1]
Length = 260
Score = 85.4 bits (208), Expect = 4e-16
Identities = 55/189 (29%), Positives = 93/189 (49%), Gaps = 8/189 (4%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G T VG++ KDGV+LA + + + ++E + KI I D IA +G + D +++
Sbjct: 34 KRGATAVGVKWKDGVVLAVEKRIT-SKLIEPSSYEKIFLIDDHIAAAPSGIIADARVLVD 92
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVDEPTIANL 119
EA+ Y+ T+G P+ + + ++ + + P+ +++ G ++P +
Sbjct: 93 RARLEAQIYRLTYGEPVPLTVLVKKICDLKQAHTQYGGVRPFGAALLMAGVNEKPELFET 152
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
DP G A GSG A+AI EE YR ++G + A +LAI A+ G
Sbjct: 153 DPSGAYFEWKAVAIGSGRNTAMAIFEEHYRDDIGKDDAIKLAILALAKTLEEPTAEG--- 209
Query: 180 IQVVTITKD 188
I+V IT D
Sbjct: 210 IEVAYITMD 218
>gb|AAF46088.1| (AE003435) CG18341 gene product [Drosophila melanogaster]
Length = 307
Score = 85.4 bits (208), Expect = 4e-16
Identities = 62/188 (32%), Positives = 96/188 (50%), Gaps = 5/188 (2%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGT+ VGI KDGVIL ADT+A+ +V N KI + D I AG+ D +MI
Sbjct: 46 KTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITL 105
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDP 121
AE ++ R + + +L L ++ ++ ++ G VD P + + P
Sbjct: 106 TTSAELDLHRLNTERRVPVVCASMMLRRTL--FRYQGHIGAALVMGGVDTTGPQLYCIYP 163
Query: 122 LGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G Y A GSGT A+++LE G++ +L +E+ K+L +A+ A D+ +GS I
Sbjct: 164 CGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGS-NID 222
Query: 182 VVTITKDG 189
+ IT G
Sbjct: 223 LCVITAKG 230
>pir||T47893 proteasome component C5 - Arabidopsis thaliana
>gi|577531|emb|CAA56201.1| (X79806) proteasome subunit
[Arabidopsis thaliana] >gi|3421120|gb|AAC32073.1|
(AF043537) 20S proteasome beta subunit PBF1 [Arabidopsis
thaliana] >gi|7329692|emb|CAB82686.1| (AL162295)
proteasome component C5 [Arabidopsis thaliana]
Length = 223
Score = 85.0 bits (207), Expect = 6e-16
Identities = 58/207 (28%), Positives = 101/207 (48%), Gaps = 16/207 (7%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T V I D ++AADT+ S + + + + KI + DR ++++G DV+ + ++L
Sbjct: 15 GGTCVAIAGSDYCVIAADTRMSTGYSILSRDYSKIHKLADRAVLSSSGFQADVKALQKVL 74
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
++ YQ + M+ AMA LLSN L ++FPY ++GG +E + D +G
Sbjct: 75 KSRHLIYQHQHNKQMSCPAMAQLLSNTLYFKRFFPYYAFNVLGGLDEEGKGCVFTYDAVG 134
Query: 124 GLIFDDYTATGSG-------------TPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGA 170
Y A GSG +P + + ++ L +A +L +A
Sbjct: 135 SYERVGYGAQGSGSTLIMPFLDNQLKSPSPLLLPKQDSNTPLSEAEAVDLVKTVFASATE 194
Query: 171 RDVYTGSKKIQVVTITKDGMKEEFVTL 197
RD+YTG K++++ + DG+K E + L
Sbjct: 195 RDIYTGD-KLEIMILKADGIKTELMDL 220
>sp|P42742|PRC5_ARATH PROTEASOME COMPONENT C5 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT C5) (TAS-F22/FAFP98) >gi|600387|emb|CAA47753.1|
(X67338) proteosome subunit [Arabidopsis thaliana]
Length = 230
Score = 85.0 bits (207), Expect = 6e-16
Identities = 58/207 (28%), Positives = 101/207 (48%), Gaps = 16/207 (7%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T V I D ++AADT+ S + + + + KI + DR ++++G DV+ + ++L
Sbjct: 22 GGTCVAIAGSDYCVIAADTRMSTGYSILSRDYSKIHKLADRAVLSSSGFQADVKALQKVL 81
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
++ YQ + M+ AMA LLSN L ++FPY ++GG +E + D +G
Sbjct: 82 KSRHLIYQHQHNKQMSCPAMAQLLSNTLYFKRFFPYYAFNVLGGLDEEGKGCVFTYDAVG 141
Query: 124 GLIFDDYTATGSG-------------TPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGA 170
Y A GSG +P + + ++ L +A +L +A
Sbjct: 142 SYERVGYGAQGSGSTLIMPFLDNQLKSPSPLLLPKQDSNTPLSEAEAVDLVKTVFASATE 201
Query: 171 RDVYTGSKKIQVVTITKDGMKEEFVTL 197
RD+YTG K++++ + DG+K E + L
Sbjct: 202 RDIYTGD-KLEIMILKADGIKTELMDL 227
>gi|6755204 proteasome beta type subunit 5 [Mus musculus]
>gi|2897806|dbj|BAA24916.1| (AB003304) PSMB5 [Mus
musculus] >gi|2897809|dbj|BAA24917.1| (AB003306) PSMB5
[Mus musculus] >gi|5757659|gb|AAD50536.1|AF060091_1
(AF060091) proteasome subunit X [Mus musculus]
Length = 264
Score = 84.7 bits (206), Expect = 7e-16
Identities = 52/185 (28%), Positives = 96/185 (51%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + GVI+AAD++A+ + + ++K+I I + T AG D R+L
Sbjct: 59 GTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 178
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
I + GSG+ +A +++ GY +L +E+A +LA +A+ A RD Y+G + +
Sbjct: 179 RISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGG-AVNLYH 237
Query: 185 ITKDG 189
+ +DG
Sbjct: 238 VREDG 242
>sp|O55234|PRCE_MOUSE PROTEASOME EPSILON CHAIN PRECURSOR (MACROPAIN EPSILON CHAIN)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX EPSILON CHAIN)
(PROTEASOME SUBUNIT X) (PROTEASOME CHAIN 6)
Length = 209
Score = 84.7 bits (206), Expect = 7e-16
Identities = 52/185 (28%), Positives = 96/185 (51%), Gaps = 2/185 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + GVI+AAD++A+ + + ++K+I I + T AG D R+L
Sbjct: 4 GTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 63
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 64 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 123
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVT 184
I + GSG+ +A +++ GY +L +E+A +LA +A+ A RD Y+G + +
Sbjct: 124 RISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGG-AVNLYH 182
Query: 185 ITKDG 189
+ +DG
Sbjct: 183 VREDG 187
>pir||B75181 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha chain
PAB0417 - Pyrococcus abyssi (strain Orsay)
>gi|5458039|emb|CAB49529.1| (AJ248284) proteasome,
subunit alpha (EC 3.4.99.46) (psmA) [Pyrococcus abyssi]
Length = 260
Score = 84.7 bits (206), Expect = 7e-16
Identities = 51/187 (27%), Positives = 95/187 (50%), Gaps = 8/187 (4%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G T VG++ KDGV+LA + + + ++E + KI I D IA ++G + D +++
Sbjct: 34 KRGATAVGVKCKDGVVLAVEKRIT-SRLIEPESYEKIFQIDDHIAAASSGIIADARVLVN 92
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVDEPTIANL 119
EA+ ++ T+G P + + ++ + + P+ +++ G D+P +
Sbjct: 93 RARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPELYET 152
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
DP G A GSG A+AI E+ YR ++ +++A +LAI A+ + ++
Sbjct: 153 DPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEK---PSAEN 209
Query: 180 IQVVTIT 186
I+V IT
Sbjct: 210 IEVAVIT 216
>pir||JS0753 multicatalytic endopeptidase complex (EC 3.4.99.46) chain pts1 -
fission yeast (Schizosaccharomyces pombe)
>gi|218552|dbj|BAA02403.1| (D13094) proteasome subunit
pts1+ [Schizosaccharomyces pombe]
>gi|742350|prf||2009376A proteasome:SUBUNIT=pts1
[Schizosaccharomyces pombe]
Length = 215
Score = 84.3 bits (205), Expect = 9e-16
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ R + G+++ D++AS ++ + ++K+I I + T AG D Q +L
Sbjct: 4 GTTTLAFRYQHGIVVCVDSRASAGPLIASQTVKKVIEINPYLLGTLAGGAADCQFWETVL 63
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPT-IANLDPLGG 124
E R +Q ++ A + +LSNI K + + ++ G T + +D G
Sbjct: 64 GMECRLHQLRNKELISVSAASKILSNITYSYKGYGLSMGTMLAGTGKGGTALYYIDSDGT 123
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ D + GSG+ FA +L+ GYR +L ++A LA +++ AA RD Y+G
Sbjct: 124 RLKGDLFSVGSGSTFAYGVLDSGYRWDLSKQEALYLAQRSIVAATHRDAYSG 175
>sp|P30655|PRCE_SCHPO PROTEASOME COMPONENT PTS1 PRECURSOR (MACROPAIN SUBUNIT PTS1)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PTS1)
>gi|7493190|pir||T38783 proteasome component pts1
precursor - fission yeast (Schizosaccharomyces pombe)
>gi|4490651|emb|CAB11483.1| (Z98762) proteasome
component pts1 precursor [Schizosaccharomyces pombe]
Length = 272
Score = 84.3 bits (205), Expect = 9e-16
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ R + G+++ D++AS ++ + ++K+I I + T AG D Q +L
Sbjct: 61 GTTTLAFRYQHGIVVCVDSRASAGPLIASQTVKKVIEINPYLLGTLAGGAADCQFWETVL 120
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPT-IANLDPLGG 124
E R +Q ++ A + +LSNI K + + ++ G T + +D G
Sbjct: 121 GMECRLHQLRNKELISVSAASKILSNITYSYKGYGLSMGTMLAGTGKGGTALYYIDSDGT 180
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ D + GSG+ FA +L+ GYR +L ++A LA +++ AA RD Y+G
Sbjct: 181 RLKGDLFSVGSGSTFAYGVLDSGYRWDLSKQEALYLAQRSIVAATHRDAYSG 232
>dbj|BAA10935.1| (D64058) nurse shark LMPX [Ginglymostoma cirratum]
Length = 259
Score = 83.9 bits (204), Expect = 1e-15
Identities = 51/172 (29%), Positives = 88/172 (50%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+G R GVI+A D++A+ V + ++K+I I + T AG D R+L
Sbjct: 55 GTTTLGFRFAHGVIVAVDSRATAGSYVASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 114
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + +I G+ P + +D G
Sbjct: 115 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 174
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + GSG+ +A +L+ YR ++ +A ELA +A+ A RD Y+G
Sbjct: 175 RVSGQIFSVGSGSVYAYGVLDRAYRHDMSPTEAYELAKQAIYHATYRDAYSG 226
>gb|AAD53521.1|AF155581_1 (AF155581) proteasome subunit beta 7 [Danio rerio]
Length = 275
Score = 83.9 bits (204), Expect = 1e-15
Identities = 62/187 (33%), Positives = 93/187 (49%), Gaps = 5/187 (2%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT GI KDGV+L ADT+A+ +V N KI I+ I AG+ D +M
Sbjct: 38 RKTGTTICGIVYKDGVVLGADTRATEGMIVADKNCSKIHYISPNIYCCGAGTAADTEMTT 97
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVD--EPTIANLD 120
+I+ + + + GR +L +L ++ Y+ ++ G VD P + ++
Sbjct: 98 QIISSNLELHSLSTGRLPRVATANRMLKQML--FRYQGYIGAALVLGGVDCTGPHLYSIY 155
Query: 121 PLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKI 180
P G Y GSG+ A+A+ E+ YR ++ E AK L A+ A D+ +GS I
Sbjct: 156 PHGSTDKLPYVTMGSGSLAAMAVFEDRYRPDMEEEDAKSLVRDAIAAGIFNDLGSGS-NI 214
Query: 181 QVVTITK 187
V ITK
Sbjct: 215 DVCVITK 221
>pir||T04497 multicatalytic endopeptidase complex (EC 3.4.99.46) beta chain -
Arabidopsis thaliana >gi|2511594|emb|CAA74028.1|
(Y13694) multicatalytic endopeptidase complex,
proteasome precursor, beta subunit [Arabidopsis
thaliana] >gi|2827525|emb|CAA16533.1| (AL021633)
multicatalytic endopeptidase complex, proteasome
precursor, beta subunit [Arabidopsis thaliana]
>gi|3421099|gb|AAC32065.1| (AF043529) 20S proteasome
subunit PBA1 [Arabidopsis thaliana]
>gi|7270032|emb|CAB79848.1| (AL161578) multicatalytic
endopeptidase complex, proteasome precursor, beta
subunit [Arabidopsis thaliana]
Length = 233
Score = 83.5 bits (203), Expect = 2e-15
Identities = 54/192 (28%), Positives = 96/192 (49%), Gaps = 6/192 (3%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTT +G+ GV+L AD++ S V KI +TD + + +GS D Q+++ +
Sbjct: 12 GTTIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQVVSDYV 71
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY--VDEPTIANLDPLG 123
+ G+P T + ANL+ + NK +I+GG+ + I + PLG
Sbjct: 72 RYFLHQHTIQHGQPATVKVSANLIRMLAYNNKNM-LQTGLIVGGWDKYEGGKIYGI-PLG 129
Query: 124 GLIFDD-YTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G + + + GSG+ + ++ ++ N+ E+A++L +KAV A ARD +G ++
Sbjct: 130 GTVVEQPFAIGGSGSSYLYGFFDQAWKDNMTKEEAEQLVVKAVSLAIARDGASGG-VVRT 188
Query: 183 VTITKDGMKEEF 194
V I +G+ F
Sbjct: 189 VIINSEGVTRNF 200
>gb|AAB87679.1| (AF032390) LMP7 [Danio rerio]
Length = 271
Score = 83.5 bits (203), Expect = 2e-15
Identities = 50/172 (29%), Positives = 90/172 (52%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++AS + + K+I I + T +GS D Q R+L
Sbjct: 67 GTTTLAFKFRHGVIVAVDSRASAGKYIASKEANKVIEINPYLLGTMSGSAADCQYWERLL 126
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
E R Y+ + ++ A + LLSN++ + + +I G+ + P + +D G
Sbjct: 127 AKECRLYKLRNKQRISVSAASKLLSNMMLGYRGMGLSMGSMICGWDKQGPGLYYVDDNGT 186
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TG G +A +++ GYR+++ +E+A EL + + A RD Y+G
Sbjct: 187 RLSGRMFSTGCGNSYAYGVVDSGYREDMTVEEAYELGRRGIAHATHRDAYSG 238
>gb|AAD53518.1|AF155578_1 (AF155578) proteasome subunit beta 5 [Danio rerio]
Length = 255
Score = 83.1 bits (202), Expect = 2e-15
Identities = 48/174 (27%), Positives = 91/174 (51%), Gaps = 1/174 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + + ++K+I I + T AG D R+L
Sbjct: 51 GTTTLAFKFQHGVIVAVDSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 110
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + LL+N++ + K + ++ G+ P + +D G
Sbjct: 111 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMVCGWDKRGPGLYYVDSEGN 170
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
+ D A GSG+ +A +++ G R +L I++A +L +A+ A RD Y+G +
Sbjct: 171 RVCGDLFAVGSGSMYAYGVVDSGLRYDLTIDEACDLGRRAIYQATYRDAYSGGQ 224
>emb|CAB96046.1| (AJ404677) proteasome beta 2 subunit [Giardia intestinalis]
Length = 238
Score = 83.1 bits (202), Expect = 2e-15
Identities = 54/190 (28%), Positives = 97/190 (50%), Gaps = 1/190 (0%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
+KTGTT +G+ K GVILAADT+++ +V N +K++ I +++ + AG+ D +
Sbjct: 29 KKTGTTIMGLTFKGGVILAADTRSTGGPVVMNKNKKKLVCINEQMYMAGAGTAADTAAVG 88
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
R+ + R + + GR ++ L+S+ L + II G + ++D
Sbjct: 89 RMAASSLRLHAYKTGRKPLVQSAVKLISDHLFRYMGYVSAYVIIAGVDYKGAHLCSIDAH 148
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G + + GSG A ++LE+ ++ ++ A E A KAV+A D+ +GS + +
Sbjct: 149 GSITAQPFVTDGSGRLAAQSMLEKHWKPDMEENDAVECACKAVEAGVFNDLGSGS-GVDL 207
Query: 183 VTITKDGMKE 192
V + DG E
Sbjct: 208 VILRLDGTSE 217
>gb|AAG16286.1|AC016024_9 (AC016024) leishmania proteasome subunit beta-2 [Leishmania major]
Length = 259
Score = 83.1 bits (202), Expect = 2e-15
Identities = 56/184 (30%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VG+ KDGV+L ADT+A+ +V RKI + I AG+ D + +
Sbjct: 32 KTGTTIVGVVYKDGVVLGADTRATEGSIVADKCCRKIHYMAPNIMCCGAGTSADTEAVTN 91
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
++ + ++ G+ LL L + ++ G V+ P +A + P G
Sbjct: 92 MVSSHLALHRLETGKQSRVLEALTLLKRHLYRYQGHVSAALVLGGVDVEGPFLATIAPHG 151
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ GSG+ A+A LE Y+ N+ E+AKEL A+ D Y+G+ ++ V
Sbjct: 152 STDRLPFVTMGSGSIAAMAQLEAAYKDNMTCEEAKELVTSAIHKGIFNDPYSGT-QVDVC 210
Query: 184 TITK 187
ITK
Sbjct: 211 VITK 214
>emb|CAC13117.1| (AJ271723) low molecular mass polypeptide subunit PSMB8 [Takifugu
rubripes]
Length = 272
Score = 83.1 bits (202), Expect = 2e-15
Identities = 49/171 (28%), Positives = 89/171 (51%), Gaps = 2/171 (1%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + K GVI+A D++AS + + + +K+I I + T +GS D R+L
Sbjct: 71 GTTTLAFKFKHGVIVAVDSRASAGKYISSQDAKKVIEINSYLLGTMSGSAADCMYWERLL 130
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGGL 125
E R Y+ ++ A + LL+N++ + V +I G+ + + +D G
Sbjct: 131 AKECRLYRLRNNHRISVAAASKLLANMMLGYRGMGLSVGSMICGW--DKQLYYVDENGNR 188
Query: 126 IFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+TGSG +A A+++ G R+++ +E+A +L + + A RD Y+G
Sbjct: 189 FSGQMFSTGSGNSYAYAVVDSGLREDMTVEEAYDLGRRGIVYATHRDAYSG 239
>gi|6755206 proteasome (prosome, macropain) subunit, beta type 7 [Mus musculus]
>gi|7435873|pir||JC6122 proteasome beta-type Z chain (EC
3.4.-.-) - mouse >gi|1632755|dbj|BAA12017.1| (D83585)
proteasome Z subunit precursor [Mus musculus]
>gi|2062107|emb|CAA71824.1| (Y10874) proteasome subunti
MC14 [Mus musculus] >gi|2547068|dbj|BAA22857.1| (D85570)
PSMB7 [Mus musculus]
Length = 277
Score = 81.9 bits (199), Expect = 5e-15
Identities = 55/185 (29%), Positives = 92/185 (49%), Gaps = 1/185 (0%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT G+ KDG++L ADT+A+ +V N KI I+ I AG+ D M
Sbjct: 40 RKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTT 99
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
+++ + + T GR +L +L + + ++ G V P + ++ P
Sbjct: 100 QLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPH 159
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G Y GSG+ A+A+ E+ +R ++ E+AK+L +A+ A D+ +GS I +
Sbjct: 160 GSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGS-NIDL 218
Query: 183 VTITK 187
I+K
Sbjct: 219 CVISK 223
>emb|CAA67761.1| (X99382) alpha proteasome [Entamoeba histolytica]
Length = 247
Score = 81.9 bits (199), Expect = 5e-15
Identities = 61/203 (30%), Positives = 103/203 (50%), Gaps = 15/203 (7%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T +GI+ K+GV+LA + + S M+ + +I KII I D I +G D + +
Sbjct: 32 KLGSTVIGIQTKEGVVLAVEKRISSPLMLGS-SIEKIIEIDDHIGAAVSGLTADARTLID 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNIL-------NENKWF--PYLVQIIIGGYVDE- 113
EA+ ++F + P+ +A +S++ + K P+ V ++I G VDE
Sbjct: 91 NARLEAQNHRFMYDEPINVEVVAQAISDLSLRFGEGSRKKKVMSRPFGVALLIAG-VDET 149
Query: 114 -PTIANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARD 172
P + DP G I ATG+GT A +IL E Y K++ + +A+ LA+ +K +
Sbjct: 150 GPRLFQTDPSGMFIEFYAKATGAGTEAAQSILHEKYNKSMTLREAEILALSTLKQ--VME 207
Query: 173 VYTGSKKIQVVTITKDGMKEEFV 195
SK ++V +T + K E +
Sbjct: 208 EKLNSKNVEVALVTVEKKKFEIM 230
>gb|AAF22654.1| (AF214525) interferon-gamma inducible proteasome subunit LMP7 [Bos
taurus]
Length = 193
Score = 81.9 bits (199), Expect = 5e-15
Identities = 50/168 (29%), Positives = 88/168 (51%), Gaps = 1/168 (0%)
Query: 10 VGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILEAEA 69
+ + + GVI+A D++AS + + TL + K+I I + T +G D R+L E
Sbjct: 1 LAFKFQHGVIVAVDSRASAGNYIATLKVNKVIEINPYLLGTMSGCAADCLYWERLLAKEC 60
Query: 70 RYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGGLIFD 128
R Y G ++ A + LLSN++ + + + +I G+ + P + +D G +
Sbjct: 61 RLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDENGTRLSG 120
Query: 129 DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ +TGSG A +++ GYR +L IE+A +L +A+ A RD Y+G
Sbjct: 121 NMFSTGSGNSHAYGVMDSGYRPDLSIEEAYDLGRRAIVHATHRDSYSG 168
>gb|AAF97811.1|AF285103_1 (AF285103) proteasome z subunit [Rattus norvegicus]
Length = 277
Score = 81.9 bits (199), Expect = 5e-15
Identities = 55/185 (29%), Positives = 92/185 (49%), Gaps = 1/185 (0%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT G+ KDG++L ADT+A+ +V N KI I+ I AG+ D M
Sbjct: 40 RKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTT 99
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
+++ + + T GR +L +L + + ++ G V P + ++ P
Sbjct: 100 QLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPH 159
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G Y GSG+ A+A+ E+ +R ++ E+AK+L +A+ A D+ +GS I +
Sbjct: 160 GSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGS-NIDL 218
Query: 183 VTITK 187
I+K
Sbjct: 219 CVISK 223
>emb|CAA10208.1| (AJ130820) proteasome subunit beta-2 [Trypanosoma brucei
rhodesiense]
Length = 255
Score = 81.5 bits (198), Expect = 6e-15
Identities = 54/184 (29%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VG+ + GV+L ADT+A+ +V +KI + I AG+ D + +
Sbjct: 27 KTGTTIVGVVFEGGVVLGADTRATEGSIVADKRCKKIHYMAPNIMCCGAGTAADTEAVTN 86
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
+ A ++ G+ LL L + ++ G V +A + P G
Sbjct: 87 MTAANLTLHRLGTGKQSRVSEALTLLKRHLYRYQGHVSAALVLGGVDVGGAFLATVAPHG 146
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ A GSG+ A+A LE GY++NL +E+AK+L + A+ D Y+G+ ++ +
Sbjct: 147 STDRLPFVAMGSGSIAAMAALETGYKENLTLEEAKQLVVSAIHKGIFNDPYSGT-QVDLC 205
Query: 184 TITK 187
ITK
Sbjct: 206 VITK 209
>sp|O59219|PRCA_PYRHO PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|7435878|pir||A71033 probable
proteasome, alpha subunit - Pyrococcus horikoshii
>gi|3257982|dbj|BAA30665.1| (AP000006) 260aa long
hypothetical proteasome, alpha subunit [Pyrococcus
horikoshii]
Length = 260
Score = 81.1 bits (197), Expect = 8e-15
Identities = 49/187 (26%), Positives = 94/187 (50%), Gaps = 8/187 (4%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G T VG++ +GV+LA + + + ++E + KI I D IA ++G + D +++
Sbjct: 34 KRGATAVGVKCNEGVVLAVEKRIT-SRLIEPESYEKIFQIDDHIAAASSGIIADARVLVN 92
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVDEPTIANL 119
EA+ ++ T+G P + + ++ + + P+ +++ G ++P +
Sbjct: 93 RARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNEKPELYET 152
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
DP G A GSG A+AI EE Y+ ++ +E+A +LAI A+ + ++
Sbjct: 153 DPSGAYFAWKAVAIGSGRNTAMAIFEEKYKDDMSLEEAIKLAIFALAKTMEK---PSAEN 209
Query: 180 IQVVTIT 186
I+V IT
Sbjct: 210 IEVAIIT 216
>gb|AAD53517.1|AF155577_1 (AF155577) proteasome subunit beta 12 [Danio rerio]
Length = 279
Score = 80.8 bits (196), Expect = 1e-14
Identities = 56/187 (29%), Positives = 90/187 (47%), Gaps = 1/187 (0%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT G+ KDGV+L ADT+A+ D +V KI I I AG+ D +
Sbjct: 40 KTGTTIAGVVFKDGVVLGADTRATSDEVVADKMCAKIHYIAPNIYCCGAGTAADTEKTTD 99
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
+L + + GR N++ ++L + I+ G + + P G
Sbjct: 100 MLSSNLTIFSMNSGRNPRVVMAVNIIQDMLFRYRGMIGANLILGGVDCTGSHLYTVGPYG 159
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ Y A GSG A+ ILE+ ++ N+ +E+AK L A++A D+ +G+ I +
Sbjct: 160 SMDKVPYLAMGSGDLAAMGILEDRFKVNMDLEQAKALVSDAIQAGIMCDLGSGN-NIDLC 218
Query: 184 TITKDGM 190
ITK+G+
Sbjct: 219 VITKEGV 225
>gi|4506203 proteasome (prosome, macropain) subunit, beta type, 7; Z [Homo
sapiens] >gi|11428779|ref|XP_005463.1| proteasome
(prosome, macropain) subunit, beta type, 7 [Homo
sapiens] >gi|1531533|dbj|BAA07238.1| (D38048) proteasome
subunit z [Homo sapiens]
Length = 277
Score = 80.4 bits (195), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 1/186 (0%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT G+ KDG++L ADT+A+ +V N KI I+ I AG+ D M
Sbjct: 40 RKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTT 99
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
+++ + + + GR +L +L + + ++ G V P + ++ P
Sbjct: 100 QLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPH 159
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G Y GSG+ A+A+ E+ +R ++ E+AK L +A+ A D+ +GS I +
Sbjct: 160 GSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGS-NIDL 218
Query: 183 VTITKD 188
I+K+
Sbjct: 219 CVISKN 224
>pir||JC5073 proteasome epsilon chain precursor - Geodia cydonium
>gi|1708783|emb|CAA66312.1| (X97728) LMP7-like protein
[Geodia cydonium]
Length = 280
Score = 80.4 bits (195), Expect = 1e-14
Identities = 48/172 (27%), Positives = 88/172 (50%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GVI+A D++A+ + + ++K+I I + T AG D R L
Sbjct: 74 GTTTLAFKFQHGVIVAVDSRATAGSWIASQTVKKVIEINPYLLGTMAGGAADCAYWERQL 133
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
R Y+ ++ A + +LSN++ K + +I G+ + P + +D G
Sbjct: 134 AFSCRVYELRNKERISVAAASKILSNMVYRYKGMGLSMGTMICGWDKKGPGLYYVDSDGS 193
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + GSG+ +A +L+ GY +L +E+A++L +A+ A RD Y+G
Sbjct: 194 RLTHHMFSVGSGSTYAYGVLDSGYSYDLSVEEARDLGKRAIYHATHRDAYSG 245
>gb|AAC32060.1| (AF043524) 20S proteasome subunit PAE1 [Arabidopsis thaliana]
>gi|6056394|gb|AAF02858.1|AC009324_7 (AC009324) 20S
proteasome subunit PAE1 [Arabidopsis thaliana]
Length = 237
Score = 80.0 bits (194), Expect = 2e-14
Identities = 45/171 (26%), Positives = 92/171 (53%), Gaps = 9/171 (5%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T +G++ K+GV+LA + + + ++E ++ KI+ I D I +G + D + +
Sbjct: 32 KLGSTAIGVKTKEGVVLAVEKRIT-SPLLEPSSVEKIMEIDDHIGCAMSGLIADARTLVE 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNIL-------NENKWFPYLVQIIIGGYVDE-PT 115
E + ++F++G PMT + L ++ E+ P+ V ++I G+ + P+
Sbjct: 91 HARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGEEESMSRPFGVSLLIAGHDENGPS 150
Query: 116 IANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVK 166
+ DP G + A GSG+ A + L+E + K+L +++A+ +A+ +K
Sbjct: 151 LYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDLSLQEAETIAVSILK 201
>dbj|BAA96832.1| (AB026561) alpha 5 subunit of 20S proteasome [Oryza sativa]
Length = 237
Score = 79.2 bits (192), Expect = 3e-14
Identities = 45/171 (26%), Positives = 91/171 (52%), Gaps = 9/171 (5%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T +G++ KDGV+LA + + + ++E ++ KI+ I + I +G + D + +
Sbjct: 32 KLGSTAIGLKTKDGVVLAVEKRVT-SPLLEPSSVEKIMEIDEHIGCAMSGLIADARTLVE 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNIL-------NENKWFPYLVQIIIGGYVDE-PT 115
E + ++F++G PMT + + ++ E+ P+ V ++I G+ + P+
Sbjct: 91 HARVETQNHRFSYGEPMTVESTTQAICDLALRFGEGDEESMSRPFGVSLLIAGHDENGPS 150
Query: 116 IANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVK 166
+ DP G + A GSG+ A + L+E Y K L +++A+ +A+ +K
Sbjct: 151 LYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQYNKELTLQEAETIALSILK 201
>emb|CAA66313.1| (X97729) LMP7-like protein [Botryllus schlosseri]
Length = 257
Score = 78.8 bits (191), Expect = 4e-14
Identities = 44/172 (25%), Positives = 89/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GV++A D++A+ + + ++K+I I + T AG D R+L
Sbjct: 56 GTTTLAFKFQHGVVVAVDSRATAGSYIASQTVKKVIEINPYLLGTMAGGAADCMFWERVL 115
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + +L+N++ K + +I G+ P + +D G
Sbjct: 116 AKQCRIYELRNKERISVAAASKILANMVYNYKGMGLSMGTMICGWDKHGPGLFYVDSDGQ 175
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + + GSG+ +A +++ GYR +L + +A +L +++ A RD Y+G
Sbjct: 176 RLKGNMFSVGSGSTYAYGVMDSGYRYDLSVAEALDLGKRSIYHATHRDAYSG 227
>pir||JC5074 proteasome epsilon chain precursor - Botryllus schlosseri
Length = 258
Score = 78.8 bits (191), Expect = 4e-14
Identities = 44/172 (25%), Positives = 89/172 (51%), Gaps = 1/172 (0%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTTT+ + + GV++A D++A+ + + ++K+I I + T AG D R+L
Sbjct: 56 GTTTLAFKFQHGVVVAVDSRATAGSYIASQTVKKVIEINPYLLGTMAGGAADCMFWERVL 115
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ R Y+ ++ A + +L+N++ K + +I G+ P + +D G
Sbjct: 116 AKQCRIYELRNKERISVAAASKILANMVYNYKGMGLSMGTMICGWDKHGPGLFYVDSDGQ 175
Query: 125 LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ + + GSG+ +A +++ GYR +L + +A +L +++ A RD Y+G
Sbjct: 176 RLKGNMFSVGSGSTYAYGVMDSGYRYDLSVAEALDLGKRSIYHATHRDAYSG 227
>gb|AAC32061.1| (AF043525) 20S proteasome subunit PAE2 [Arabidopsis thaliana]
>gi|9279577|dbj|BAB01035.1| (AB022220) 20S proteasome
subunit PAE-like protein [Arabidopsis thaliana]
Length = 237
Score = 78.4 bits (190), Expect = 5e-14
Identities = 44/171 (25%), Positives = 92/171 (53%), Gaps = 9/171 (5%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T +G++ K+GV+LA + + + ++E ++ KI+ I D I +G + D + +
Sbjct: 32 KLGSTAIGVKTKEGVVLAVEKRIT-SPLLEPSSVEKIMEIDDHIGCAMSGLIADARTLVE 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNIL-------NENKWFPYLVQIIIGGYVDE-PT 115
E + ++F++G PMT + L ++ E+ P+ V ++I G+ + P+
Sbjct: 91 HARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGEEESMSRPFGVSLLIAGHDENGPS 150
Query: 116 IANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVK 166
+ DP G + A GSG+ A + L+E + K++ +++A+ +A+ +K
Sbjct: 151 LYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDITLQEAETIAVSILK 201
>gb|AAC35983.1| (AF088915) proteasome beta subunit [Petunia x hybrida]
Length = 223
Score = 78.4 bits (190), Expect = 5e-14
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 16/207 (7%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G T V + D ++AADT+ S + + T + KII + D+ + ++G DV+ + ++L
Sbjct: 15 GGTCVAVAGADYCVIAADTRMSTGYNILTRDYSKIIKLADKCVMASSGFQADVRALQKVL 74
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
+ YQ + M+ AM LLSN L ++FPY ++GG E + D +G
Sbjct: 75 ASRHLIYQHQHNKQMSCPAMGQLLSNTLYYKRFFPYYSFNVLGGLDSEGKGCVFTYDAVG 134
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRK-------------NLGIEKAKELAIKAVKAAGA 170
Y++ GSG+ + L+ + L +A +L +A
Sbjct: 135 SYERVGYSSQGSGSTLIMPFLDNQLKSPSPLLLPAQDAVTPLSEAEAIDLVKTCFASATE 194
Query: 171 RDVYTGSKKIQVVTITKDGMKEEFVTL 197
RD+YTG ++++V + G++ E + L
Sbjct: 195 RDIYTGD-RLEIVILNASGIRREEMEL 220
>dbj|BAA19759.1| (D87687) LMP2 [Xenopus laevis]
Length = 215
Score = 78.0 bits (189), Expect = 7e-14
Identities = 50/193 (25%), Positives = 90/193 (45%), Gaps = 3/193 (1%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGTT + + GV+L +D++ S V K+ P+ RI +GS D Q +A +
Sbjct: 15 TGTTIIAVEFDGGVVLGSDSRVSAGDAVVNRVFNKLAPVHQRIYCALSGSAADAQAVADM 74
Query: 65 LEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGG 124
+ P A ANL+ I + K + +I+ G+ + LGG
Sbjct: 75 AHYHMEVHSIEMEAPPLVLAAANLIKGISYKYK-EEIMAHLIVAGWDRKHGGQVYGTLGG 133
Query: 125 LIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+I +T GSG+ + ++ ++ + E+ + A++A+ A RD +G I +V
Sbjct: 134 MIIRQPFTIGGSGSTYIYGFVDSKFKPGMSREECERFAVQALSLAMERDGSSGG-VIYLV 192
Query: 184 TITKDGMKEEFVT 196
T+TK+G K+ ++
Sbjct: 193 TVTKEGTKDSIIS 205
>emb|CAA05209.1| (AJ002142) proteasome Z subunit [Ciona intestinalis]
Length = 276
Score = 78.0 bits (189), Expect = 7e-14
Identities = 57/193 (29%), Positives = 91/193 (46%), Gaps = 2/193 (1%)
Query: 3 RKTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIA 62
RKTGTT VG+ + GVIL ADT+A+ D +V N KI I I AG+ D +M
Sbjct: 37 RKTGTTIVGMVFEGGVILGADTRATEDTIVADKNCSKIHYIAPNIYCCGAGTAADTEMTT 96
Query: 63 RILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPL 122
+++ + + ++ GRP +L L + ++ G + + ++ P
Sbjct: 97 QMISSNLQLLRYNTGRPTRVATANRMLKQYLYRYQGHVSAALVLGGVDCNGAHLYSIHPH 156
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
G Y GSG+ A+A E GY+ N+ +A +L AV A D+ +GS
Sbjct: 157 GSTDKLPYVTMGSGSLAAMATFEMGYKPNMKRPEAMKLVRDAVAAGIFNDLGSGSN--VD 214
Query: 183 VTITKDGMKEEFV 195
+ I + MK E++
Sbjct: 215 LCIIGNNMKVEYL 227
>sp|O26782|PRCA_METTH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|7435881|pir||D69191 proteasome, alpha
subunit - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621771|gb|AAB85191.1| (AE000848)
proteasome, alpha subunit [Methanobacterium
thermoautotrophicum]
Length = 248
Score = 78.0 bits (189), Expect = 7e-14
Identities = 54/185 (29%), Positives = 90/185 (48%), Gaps = 6/185 (3%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K GTT++G++ K+G++L D + + +VE +I KI I + I T+G V D + I
Sbjct: 33 KRGTTSLGVKSKEGIVLVVDKRPT-SKLVEPKSIEKIFQIDEHIGAATSGLVADARAIIE 91
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNI----LNENKWFPYLVQIIIGGYVDEPT-IAN 118
EA+ + T+ P+ ++A + ++ P+ +IIGG +
Sbjct: 92 KARLEAQINRITYNEPIRVESLAKKICDMKQMYTQHGGVRPFGTALIIGGVNGRGCRLFE 151
Query: 119 LDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
DP G LI TA G+G P A+ E+ Y ++ + +A ELA+ AV A S
Sbjct: 152 TDPSGALIEYKATAIGAGRPAAMEEFEKKYSDDMNLNQAIELALDAVYEATEGKTTPESV 211
Query: 179 KIQVV 183
+I V+
Sbjct: 212 EIAVI 216
>emb|CAC13118.1| (AJ271723) low molecular mass polypeptide subunit PSMB10 [Takifugu
rubripes]
Length = 275
Score = 78.0 bits (189), Expect = 7e-14
Identities = 59/190 (31%), Positives = 89/190 (46%), Gaps = 11/190 (5%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT G+ KDGV+L ADT+A+ +V KI I I AG+ D Q
Sbjct: 39 KTGTTIAGVVFKDGVVLGADTRATSSEVVADKMCAKIHYIAPNIYCCGAGTAADTQKTTD 98
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQI----IIGGY-VDEPTIAN 118
+L + + GR N+L + L + Y QI I+GG +
Sbjct: 99 LLSSNLTIFSLNSGRKPRVVMAVNILQDTL-----YRYHGQIGANLILGGVDCTGNHLYK 153
Query: 119 LDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
+ P G + Y GSG A+ ILE+G++ ++ +E+A EL A+ A D+ +G+
Sbjct: 154 VGPYGSVDKVPYLTMGSGDLAALGILEDGFKHDMEVERATELVRLAIHAGIMSDLGSGN- 212
Query: 179 KIQVVTITKD 188
I + IT+D
Sbjct: 213 NIDICVITRD 222
>sp|P34286|YKK9_CAEEL HYPOTHETICAL 63.1 KD PROTEIN C02F5.9 IN CHROMOSOME III
>gi|630515|pir||S44611 C02F5.9 protein - Caenorhabditis
elegans >gi|289616|gb|AAA27924.1| (L14745) homology with
proteasome component C5; coded for by C. elegans cDNAs
GenBank:M80127 and T01498; putative [Caenorhabditis
elegans]
Length = 564
Score = 77.6 bits (188), Expect = 9e-14
Identities = 55/187 (29%), Positives = 96/187 (50%), Gaps = 15/187 (8%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHM-VETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
G +T I ++ I+A+DT+ + + + + T + KI + D I +TT+G GDV + ++
Sbjct: 51 GGSTCAISGENFAIVASDTRMTQNDINILTRDAEKIQILNDNIILTTSGFYGDVLQLKKV 110
Query: 65 LEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE---PTIANLDP 121
L++ Y+F + M+ A LLS L ++FPY I+ G +DE + + DP
Sbjct: 111 LQSRLHKYRFDYRSDMSVDLCAELLSRNLYYRRFFPYYTGAILAG-IDEHGKGAVFSYDP 169
Query: 122 LGGLIFDDYTATGSGTPFAIAILE---------EGY-RKNLGIEKAKELAIKAVKAAGAR 171
+G + Y+A+G+ P I L+ EGY R L +++A L + + A R
Sbjct: 170 IGCIERLGYSASGAAEPMIIPFLDCQIGHVTLSEGYERPELTLDRAISLMKDSFRGAAER 229
Query: 172 DVYTGSK 178
++ TG K
Sbjct: 230 EISTGDK 236
>sp|P40304|PRC5_DROME PROTEASOME 26 KD SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 26
KD SUBUNIT) >gi|392868|gb|AAC46465.1| (U00790)
proteasome subunit [Drosophila melanogaster]
Length = 235
Score = 77.6 bits (188), Expect = 9e-14
Identities = 57/205 (27%), Positives = 98/205 (47%), Gaps = 14/205 (6%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G + V I D ++AADT+ S + + + K+ ++ + + +AG D + +
Sbjct: 29 GGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSI 88
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
+ + Y+ T R MTT A+A +LS + ++FPY V I+ G +E + + DP+G
Sbjct: 89 KVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIG 148
Query: 124 GLIFDDYTATGSGTPFAIAILEEGY-RKNLGIEKA------KELAIKAVK----AAGARD 172
Y A G+ +L+ KN+ +E A KE A+ +A RD
Sbjct: 149 HCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKEWAVSVASDTFISAAERD 208
Query: 173 VYTGSKKIQVVTITKDGMKEEFVTL 197
+YTG + + ITKDG++ +TL
Sbjct: 209 IYTGD-SVLINIITKDGIEVRTLTL 232
>gi|11498101 proteasome, subunit alpha (psmA) [Archaeoglobus fulgidus]
>gi|6093781|sp|O29760|PRCA_ARCFU PROTEASOME ALPHA
SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX ALPHA
SUBUNIT) >gi|7435882|pir||B69311 proteasome, subunit
alpha (psmA) homolog - Archaeoglobus fulgidus
>gi|2650136|gb|AAB90747.1| (AE001070) proteasome,
subunit alpha (psmA) [Archaeoglobus fulgidus]
Length = 246
Score = 77.6 bits (188), Expect = 9e-14
Identities = 48/166 (28%), Positives = 80/166 (47%), Gaps = 5/166 (3%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G T +GI+ K+GVIL AD + ++E I KI I + I T+G V D +++
Sbjct: 32 KRGATAIGIKCKEGVILIADKRVG-SKLLEADTIEKIYKIDEHICAATSGLVADARVLID 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVDEPTIANL 119
EA+ + T+ P+T + +A + + + + P+ V ++I G + P +
Sbjct: 91 RARIEAQINRLTYDEPITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVDEVPKLYET 150
Query: 120 DPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAV 165
DP G L+ TA G G E+ YR +L + A L + A+
Sbjct: 151 DPSGALLEYKATAIGMGRNAVTEFFEKEYRDDLSFDDAMVLGLVAM 196
>gb|AAF49435.1| (AE003526) Pros26 gene product [Drosophila melanogaster]
Length = 235
Score = 77.6 bits (188), Expect = 9e-14
Identities = 57/205 (27%), Positives = 98/205 (47%), Gaps = 14/205 (6%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G + V I D ++AADT+ S + + + K+ ++ + + +AG D + +
Sbjct: 29 GGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSI 88
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLG 123
+ + Y+ T R MTT A+A +LS + ++FPY V I+ G +E + + DP+G
Sbjct: 89 KVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIG 148
Query: 124 GLIFDDYTATGSGTPFAIAILEEGY-RKNLGIEKA------KELAIKAVK----AAGARD 172
Y A G+ +L+ KN+ +E A KE A+ +A RD
Sbjct: 149 HCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDTFISAAERD 208
Query: 173 VYTGSKKIQVVTITKDGMKEEFVTL 197
+YTG + + ITKDG++ +TL
Sbjct: 209 IYTGD-SVLINIITKDGIEVRTLTL 232
>emb|CAC13120.1| (AJ271723) low molecular mass polypeptide subunit PSMB9 [Takifugu
rubripes]
Length = 216
Score = 77.6 bits (188), Expect = 9e-14
Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 3/192 (1%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGTT + + DGV+L +D++ S V + K+ P+ D+I +GS D Q IA I
Sbjct: 16 TGTTIIAVEFDDGVVLGSDSRVSAGKAVVNRVMNKLSPLHDKIYCALSGSAADAQTIAEI 75
Query: 65 LEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGG 124
+ + + G R+ ANL+ NI + K + +I+ G+ L G
Sbjct: 76 VNYQLDVHSVEIGEDPLVRSAANLVKNISYKYK-EELMAHLIVAGWDKRKGGQVFATLNG 134
Query: 125 LIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
L+ + GSG+ + ++ YRK + E+A++ + + A RD +G +V
Sbjct: 135 LLTRQPFAVGGSGSSYVYGFVDAEYRKGMSKEEAQQFVVNTLSLAMNRDGSSGG-VAYIV 193
Query: 184 TITKDGMKEEFV 195
TI + +E+ +
Sbjct: 194 TIDEHNAEEKVI 205
>gb|AAF70292.1|AF255338_1 (AF255338) 20S proteasome subunit [Glycine max]
Length = 237
Score = 76.5 bits (185), Expect = 2e-13
Identities = 44/171 (25%), Positives = 92/171 (53%), Gaps = 9/171 (5%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T +G++ K+GV+LA + + + ++E ++ KI+ I + I +G + D + +
Sbjct: 32 KLGSTAIGLKTKEGVVLAVEKRIT-SPLLEPSSVEKIMEIDEHIGCAMSGLIADARTLVE 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNIL-------NENKWFPYLVQIIIGGYVDE-PT 115
E + ++F++G PMT + L ++ E+ P+ V ++I G+ + P+
Sbjct: 91 HARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGDEESMSRPFGVSLLIAGHDENGPS 150
Query: 116 IANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVK 166
+ DP G + A GSG+ A + L+E + K+L +++A+ +A+ +K
Sbjct: 151 LYYTDPSGTFWQCNGKAIGSGSEGADSSLQEQFNKDLTLQEAETIALSILK 201
>sp|Q59565|PRCA_METTE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|11265947|pir||T48878 proteasome psmA,
alpha chain [validated] - Methanosarcina thermophila
>gi|1002689|gb|AAA93166.1| (U30483) PsmA [Methanosarcina
thermophila]
Length = 247
Score = 74.5 bits (180), Expect = 8e-13
Identities = 51/187 (27%), Positives = 89/187 (47%), Gaps = 6/187 (3%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K GTT VGI+ DGV+L D + + +VE +I KI I D I T+G V D + +
Sbjct: 31 KRGTTAVGIKAADGVVLLVDKRIT-SRLVEAESIEKIFQIDDHIGAATSGLVADARALVD 89
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVDE-PTIAN 118
EA+ + ++ + ++ + + + PY ++I G D+ P +
Sbjct: 90 RARVEAQVNRVSYDELIGVEVISKKICDHKQTYTQYGGVRPYGTALLIAGVDDKRPRLFE 149
Query: 119 LDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
DP G L+ TA G+G + + E Y++++ IE A L + A+ A G+
Sbjct: 150 TDPSGALLEYKATAIGAGRNAVVEVFEADYKEDMNIEAAILLGMDALYKAAEGKFDAGTL 209
Query: 179 KIQVVTI 185
++ VV++
Sbjct: 210 EVGVVSL 216
>gi|6755202 proteasome (prosome, macropain) subunit, beta type, 3 [Mus
musculus] >gi|9910831|sp|Q9R1P1|PRCT_MOUSE PROTEASOME
THETA CHAIN (MACROPAIN THETA CHAIN) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX THETA CHAIN) (PROTEASOME CHAIN 13)
(PROTEASOME COMPONENT C10-II)
>gi|5757661|gb|AAD50537.1|AF060092_1 (AF060092)
proteasome subunit C10-II [Mus musculus]
Length = 205
Score = 74.5 bits (180), Expect = 8e-13
Identities = 52/187 (27%), Positives = 94/187 (49%), Gaps = 5/187 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G + ++ K+ V +AAD + + + T + +KI P+ DR+ I AG DVQ +A+ L
Sbjct: 8 GGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRL 67
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY---VDEPTIANLDPL 122
+ Y+ GR + + ++++N+L E ++ PY + +I G +P I +LD +
Sbjct: 68 KFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLI 127
Query: 123 G-GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G ++ DD+ +G+ + + E + N+ E E +A+ A RD +G I
Sbjct: 128 GCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVI- 186
Query: 182 VVTITKD 188
V I KD
Sbjct: 187 VHVIEKD 193
>gb|AAD53516.1|AF155576_1 (AF155576) proteasome subunit beta 11 [Danio rerio]
Length = 217
Score = 74.5 bits (180), Expect = 8e-13
Identities = 48/195 (24%), Positives = 98/195 (49%), Gaps = 15/195 (7%)
Query: 5 TGTTTVGIRVKDGVILAADTQASL-DHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
TGTT + ++ GVI+ +D++AS+ + V + I K+I + DRI AGS+ D Q + +
Sbjct: 15 TGTTILAVKFNGGVIIGSDSRASMGESYVSSKTINKLIQVHDRIFCCIAGSLADAQAVTK 74
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-------PTI 116
+ + + ++ P +A A+++ + NK + + G++ P I
Sbjct: 75 MAKFQLSFHSIQMESPPLVKAAASIMRELCYSNK------EELRAGFITAGWDRKKGPQI 128
Query: 117 ANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ G L+ +T GSG+ + ++ ++ ++ +E+A + + A+ A RD +G
Sbjct: 129 YVVSLGGMLLSQPFTIGGSGSTYIYGYVDAKFKPDMTLEEATQFSTNALALAMGRDNVSG 188
Query: 177 SKKIQVVTITKDGMK 191
+ +V IT+ G+K
Sbjct: 189 G-VVHLVVITEAGVK 202
>gb|AAF49685.1| (AE003532) Prosbeta2 gene product [Drosophila melanogaster]
Length = 272
Score = 74.5 bits (180), Expect = 8e-13
Identities = 55/190 (28%), Positives = 94/190 (48%), Gaps = 5/190 (2%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VGI KDGVIL ADT+A+ +V N KI + I AG+ D +M
Sbjct: 37 KTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTD 96
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDP 121
++ ++ ++ R + A +L +L ++ ++ ++ G VD+ P I ++ P
Sbjct: 97 LISSQLELHRLQTDREVRVVAANTMLKQML--FRYQGHISAALVLGGVDKTGPHIYSIHP 154
Query: 122 LGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G Y GSG+ A+ + E ++ +L E+ K+L A+ + D+ +GS I
Sbjct: 155 HGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGS-NID 213
Query: 182 VVTITKDGMK 191
+ I K ++
Sbjct: 214 LCVIRKGSVE 223
>gi|8394082 proteasome (prosome, macropain) subunit, beta type, 3 [Rattus
norvegicus] >gi|730380|sp|P40112|PRCT_RAT PROTEASOME
THETA CHAIN (MACROPAIN THETA CHAIN) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX THETA CHAIN) (PROTEASOME CHAIN 13)
(PROTEASOME COMPONENT C10-II) >gi|631877|pir||S40468
proteasome subunit RC10-Ii - rat
>gi|458731|dbj|BAA04824.1| (D21800) proteasome subunit
RC10-II [Rattus sp.]
Length = 205
Score = 74.1 bits (179), Expect = 1e-12
Identities = 52/187 (27%), Positives = 94/187 (49%), Gaps = 5/187 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G + ++ K+ V +AAD + + + T + +KI P+ DR+ I AG DVQ +A+ L
Sbjct: 8 GGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRL 67
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY---VDEPTIANLDPL 122
+ Y+ GR + + ++++N+L E ++ PY + +I G +P I +LD +
Sbjct: 68 KFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLI 127
Query: 123 G-GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G ++ DD+ +G+ + + E + N+ E E +A+ A RD +G I
Sbjct: 128 GCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVI- 186
Query: 182 VVTITKD 188
V I KD
Sbjct: 187 VHIIEKD 193
>gb|AAC32074.1| (AF043538) 20S proteasome beta subunit PBG1 [Arabidopsis thaliana]
Length = 246
Score = 74.1 bits (179), Expect = 1e-12
Identities = 53/191 (27%), Positives = 93/191 (47%), Gaps = 7/191 (3%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGT+ V I+ KDGV++A+D S + NI ++ I + +G + D Q I R
Sbjct: 30 TGTSVVAIKYKDGVLMASDMGGSYGSTLRYKNIERVKAIGKHSLLGASGEISDFQEILRY 89
Query: 65 LEAEARYYQFTW--GRPMTTRAMANLLSNIL--NENKWFPYLVQIIIGGYVDEPTIANLD 120
L+ E W G + + + N L+ ++ NK+ P +++GG + + +
Sbjct: 90 LD-ELTLNDNMWDDGNSLGPKEIHNYLTRVMYNRRNKFNPLWNTLVLGGVKNGKSYLGMV 148
Query: 121 PLGGLIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
+ G+ F DD+ ATG G A IL + + +L E +L K ++ RD + K
Sbjct: 149 SMIGVSFEDDHVATGFGNHLARPILRDEWHADLSFEDGVKLLEKCMRVLLYRD-RSAINK 207
Query: 180 IQVVTITKDGM 190
+Q+ IT++G+
Sbjct: 208 LQIAKITEEGV 218
>gb|AAC64284.1|AAC64284 (AF086832) 20S proteasome beta-subunit precursor [Streptomyces
coelicolor A3(2)] >gi|6119686|emb|CAB59497.1| (AL132648)
20S proteasome beta-subunit precursor [Streptomyces
coelicolor A3(2)]
Length = 281
Score = 74.1 bits (179), Expect = 1e-12
Identities = 53/199 (26%), Positives = 95/199 (47%), Gaps = 13/199 (6%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTT V + GV+LA D +A++ +M+ +I K+ P + A+ AG+ G + ++
Sbjct: 53 GTTIVAVTFPGGVVLAGDRRATMGNMIAQRDIEKVFPADEYSAVGIAGTAGLAVEMVKLF 112
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPY----LVQIIIGGYVD--EPTIANL 119
+ E +++ G ++ AN LS ++ N +V + G VD I +
Sbjct: 113 QLELEHFEKVEGAQLSLEGKANRLSTMIRSNLGMAMQGLAVVPLFAGYDVDRGRGRIFSY 172
Query: 120 DPLGGLIFD-DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
D GG + + TGSG+ FA +++ +R +L E+A L ++A+ A D TG
Sbjct: 173 DVTGGRSEERHFATTGSGSVFARGAMKKLFRDDLTEEQATTLVVQALYDAADDDSATGGP 232
Query: 179 KIQ------VVTITKDGMK 191
+ + IT+DG +
Sbjct: 233 DVARRIYPIITVITEDGFR 251
>dbj|BAA96835.1| (AB026564) beta 2 subunit of 20S proteasome [Oryza sativa]
Length = 272
Score = 74.1 bits (179), Expect = 1e-12
Identities = 50/184 (27%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VG+ +DGV+L ADT+A+ +V N KI + I AG+ D + +
Sbjct: 36 KTGTTIVGLVFQDGVVLGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTD 95
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
++ ++ + +++ GR LL + L + ++ G V P + + P G
Sbjct: 96 MVSSQLQLHRYATGRESRVVTSLTLLKSHLFSYQGHVSAALVLGGVDVTGPHLHTVYPHG 155
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ GSG+ A+++ E Y++ L E+ +L +A++ D+ +GS + V
Sbjct: 156 STDTLPFATMGSGSLAAMSVFESKYKEGLTREEGIQLVAEAIRGGIFNDLGSGS-NVDVC 214
Query: 184 TITK 187
ITK
Sbjct: 215 VITK 218
>gb|AAC32067.1| (AF043531) 20S proteasome beta subunit PBB2 [Arabidopsis thaliana]
>gi|9758084|dbj|BAB08528.1| (AB009052) 20S proteasome
beta subunit PBB2 [Arabidopsis thaliana]
Length = 274
Score = 73.7 bits (178), Expect = 1e-12
Identities = 53/189 (28%), Positives = 91/189 (48%), Gaps = 2/189 (1%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VG+ KDGVIL ADT+A+ +V N KI + I AG+ D + +
Sbjct: 37 KTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTD 96
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
++ ++ R +++ GR LL L + ++ G + P + + P G
Sbjct: 97 MVSSQLRLHRYQTGRDSRVVTALTLLKKHLFSYQGHVSAALVLGGVDITGPHLHTIYPHG 156
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ GSG+ A+++ E Y++ L ++ +L +A+ + D+ +GS + +
Sbjct: 157 STDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAEAICSGIFNDLGSGS-NVDIC 215
Query: 184 TITKDGMKE 192
ITK G KE
Sbjct: 216 VITK-GHKE 223
>gb|AAG26927.1|AC058785_3 (AC058785) 20S proteasome beta subunit (PBG1) [Arabidopsis
thaliana]
Length = 246
Score = 73.7 bits (178), Expect = 1e-12
Identities = 53/191 (27%), Positives = 93/191 (47%), Gaps = 7/191 (3%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGT+ V I+ KDGV++A+D S + NI ++ I + +G + D Q I R
Sbjct: 30 TGTSIVAIKYKDGVLMASDMGGSYGSTLRYKNIERVKAIGKHSLLGASGEISDFQEILRY 89
Query: 65 LEAEARYYQFTW--GRPMTTRAMANLLSNIL--NENKWFPYLVQIIIGGYVDEPTIANLD 120
L+ E W G + + + N L+ ++ NK+ P +++GG + + +
Sbjct: 90 LD-ELTLNDNMWDDGNSLGPKEIHNYLTRVMYNRRNKFNPLWNTLVLGGVKNGKSYLGMV 148
Query: 121 PLGGLIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKK 179
+ G+ F DD+ ATG G A IL + + +L E +L K ++ RD + K
Sbjct: 149 SMIGVSFEDDHVATGFGNHLARPILRDEWHADLSFEDGVKLLEKCMRVLLYRD-RSAINK 207
Query: 180 IQVVTITKDGM 190
+Q+ IT++G+
Sbjct: 208 LQIAKITEEGV 218
>sp|O73817|PRCT_ONCMY PROTEASOME THETA CHAIN (MACROPAIN THETA CHAIN) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX THETA CHAIN) (PROTEASOME CHAIN 13)
(PROTEASOME COMPONENT C10-II) >gi|3063687|gb|AAC14141.1|
(AF058707) proteasome subunit C10-11 [Oncorhynchus
mykiss]
Length = 205
Score = 73.4 bits (177), Expect = 2e-12
Identities = 50/187 (26%), Positives = 94/187 (49%), Gaps = 5/187 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G + ++ K V +AAD + + + T + +KI P+ DR+ I AG DVQ +++ L
Sbjct: 8 GGAVMAMKGKQCVAIAADRRFGVQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVSQRL 67
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY---VDEPTIANLDPL 122
+ Y+ GR + + +++SN+L E ++ PY ++ +I G EP I +LD +
Sbjct: 68 KFRLNLYELKEGRQIKPKTFMSMVSNLLYERRFGPYYIEPVIAGLDPKTFEPFICSLDLI 127
Query: 123 G-GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G ++ +D+ +G+ + + E + ++ E E +A+ A RD +G +
Sbjct: 128 GCPMVTEDFVVSGTCSEQMYGMCESLWEPDMEPEDLFETISQAMLNAVDRDAVSG-MGVV 186
Query: 182 VVTITKD 188
V I KD
Sbjct: 187 VQVIEKD 193
>gi|6324731 putative proteasome subunit; Pup1p [Saccharomyces cerevisiae]
>gi|130879|sp|P25043|PRCF_YEAST PROTEASOME COMPONENT
PUP1 PRECURSOR (MACROPAIN SUBUNIT PUP1) (PROTEINASE YSCE
SUBUNIT PUP1) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT PUP1) >gi|422175|pir||S26996 probable
multicatalytic endopeptidase complex (EC 3.4.99.46)
chain PUP1 - yeast (Saccharomyces cerevisiae)
>gi|4250|emb|CAA43492.1| (X61189) PUP1 [Saccharomyces
cerevisiae] >gi|1293717|gb|AAC49643.1| (U55020) Pup1p
[Saccharomyces cerevisiae] >gi|1420391|emb|CAA99363.1|
(Z75065) ORF YOR157c [Saccharomyces cerevisiae]
Length = 261
Score = 73.0 bits (176), Expect = 2e-12
Identities = 57/196 (29%), Positives = 101/196 (51%), Gaps = 23/196 (11%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGTT VG++ +GV++AADT+++ +V N K+ I+ +I AG+ D + + ++
Sbjct: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87
Query: 65 LEAEARYYQ-FTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
+ + + +T P A+ L ++ F Y Q IG Y+ +A +DP G
Sbjct: 88 IGSNIELHSLYTSREPRVVSALQMLKQHL------FKY--QGHIGAYL---IVAGVDPTG 136
Query: 124 GLIFD----------DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDV 173
+F Y + GSG+ A+A+LE ++++L E+A +LA A++A D+
Sbjct: 137 SHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDL 196
Query: 174 YTGSK-KIQVVTITKD 188
+GS + V+ I KD
Sbjct: 197 GSGSNVDVCVMEIGKD 212
>sp|P25156|PRCA_THEAC PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|1076173|pir||S55350 multicatalytic
endopeptidase complex (EC 3.4.99.46) alpha chain -
Thermoplasma acidophilum >gi|1633359|pdb|1PMA|A Chain A,
Proteasome From Thermoplasma Acidophilum
>gi|1633361|pdb|1PMA|C Chain C, Proteasome From
Thermoplasma Acidophilum >gi|1633362|pdb|1PMA|D Chain D,
Proteasome From Thermoplasma Acidophilum
>gi|1633363|pdb|1PMA|E Chain E, Proteasome From
Thermoplasma Acidophilum >gi|1633364|pdb|1PMA|F Chain F,
Proteasome From Thermoplasma Acidophilum
>gi|1633365|pdb|1PMA|G Chain G, Proteasome From
Thermoplasma Acidophilum >gi|1633366|pdb|1PMA|H Chain H,
Proteasome From Thermoplasma Acidophilum
>gi|1633367|pdb|1PMA|I Chain I, Proteasome From
Thermoplasma Acidophilum >gi|1633368|pdb|1PMA|J Chain J,
Proteasome From Thermoplasma Acidophilum
>gi|1633369|pdb|1PMA|K Chain K, Proteasome From
Thermoplasma Acidophilum >gi|1633370|pdb|1PMA|L Chain L,
Proteasome From Thermoplasma Acidophilum
>gi|1633371|pdb|1PMA|M Chain M, Proteasome From
Thermoplasma Acidophilum >gi|1633372|pdb|1PMA|N Chain N,
Proteasome From Thermoplasma Acidophilum
>gi|1633373|pdb|1PMA|O Chain O, Proteasome From
Thermoplasma Acidophilum >gi|395159|emb|CAA42094.1|
(X59507) alpha-subunit of the proteasome [Thermoplasma
acidophilum] >gi|10640633|emb|CAC12411.1| (AL445067)
proteasome alpha subunit [Thermoplasma acidophilum]
Length = 233
Score = 72.6 bits (175), Expect = 3e-12
Identities = 48/171 (28%), Positives = 90/171 (52%), Gaps = 8/171 (4%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T +G++ +GV+L +D + ++E +I KI I D +A T+G V D +++
Sbjct: 32 KKGSTALGMKFANGVLLISDKKVR-SRLIEQNSIEKIQLIDDYVAAVTSGLVADARVLVD 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVDE--PTIA 117
A+ + T+G + + +++ + + + PY V +I G +D+ P +
Sbjct: 91 FARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAG-IDQIGPRLF 149
Query: 118 NLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAA 168
+ DP G + TA GSG ++ LE Y++NL ++A L IKA+K++
Sbjct: 150 DCDPAGTINEYKATAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSS 200
>gi|4506197 proteasome (prosome, macropain) subunit, beta type, 3; Proteasome
subunit, beta type, 3 [Homo sapiens]
>gi|1709763|sp|P49720|PRCT_HUMAN PROTEASOME THETA CHAIN
(MACROPAIN THETA CHAIN) (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX THETA CHAIN) (PROTEASOME CHAIN 13) (PROTEASOME
COMPONENT C10-II) >gi|1082466|pir||S50149 HsC10-II
protein - human >gi|7513167|pir||S55041 multicatalytic
endopeptidase complex (EC 3.4.99.46) beta chain C10-II -
human >gi|565647|dbj|BAA05645.1| (D26598) proteasome
subunit HsC10-II [Homo sapiens]
>gi|1091575|prf||2021261C proteasome:SUBUNIT=HsC10-II
[Homo sapiens]
Length = 205
Score = 72.6 bits (175), Expect = 3e-12
Identities = 51/187 (27%), Positives = 93/187 (49%), Gaps = 5/187 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G + ++ K+ V +AAD + + + T + +KI P+ DR+ I AG DVQ +A+ L
Sbjct: 8 GGAVMAMKGKNCVAIAADRRFGIQAQLVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRL 67
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY---VDEPTIANLDPL 122
+ Y+ GR + + ++++N+L E ++ PY + +I G +P I +LD +
Sbjct: 68 KFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLI 127
Query: 123 G-GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G ++ DD+ +G+ + E + N+ + E +A+ A RD +G I
Sbjct: 128 GCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVI- 186
Query: 182 VVTITKD 188
V I KD
Sbjct: 187 VHIIEKD 193
>emb|CAA73621.1| (Y13178) multicatalytic endopeptidase [Arabidopsis thaliana]
Length = 273
Score = 72.6 bits (175), Expect = 3e-12
Identities = 52/189 (27%), Positives = 91/189 (47%), Gaps = 2/189 (1%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VG+ KDGVIL ADT+A+ +V N KI + I AG+ D + +
Sbjct: 37 KTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTD 96
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
++ ++ R +++ GR LL L + ++ G + P + + P G
Sbjct: 97 MVSSQLRLHRYQTGRDSRVITALTLLKKHLFSYQGHVSAALVLGGVDITGPHLHTIYPHG 156
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ GSG+ A+++ E Y++ L ++ +L +++ + D+ +GS + +
Sbjct: 157 STDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAESICSGIFNDLGSGS-NVDIC 215
Query: 184 TITKDGMKE 192
ITK G KE
Sbjct: 216 VITK-GNKE 223
>gb|AAC32066.1| (AF043530) 20S proteasome beta subunit PBB1 [Arabidopsis thaliana]
>gi|7939516|dbj|BAA95719.1| (AB024028) 20S proteasome
beta subunit / multicatalytic endopeptidase [Arabidopsis
thaliana]
Length = 273
Score = 72.6 bits (175), Expect = 3e-12
Identities = 52/189 (27%), Positives = 91/189 (47%), Gaps = 2/189 (1%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VG+ KDGVIL ADT+A+ +V N KI + I AG+ D + +
Sbjct: 37 KTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTD 96
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
++ ++ R +++ GR LL L + ++ G + P + + P G
Sbjct: 97 MVSSQLRLHRYQTGRDSRVITALTLLKKHLFSYQGHVSAALVLGGVDITGPHLHTIYPHG 156
Query: 124 GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ GSG+ A+++ E Y++ L ++ +L +++ + D+ +GS + +
Sbjct: 157 STDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAESICSGIFNDLGSGS-NVDIC 215
Query: 184 TITKDGMKE 192
ITK G KE
Sbjct: 216 VITK-GNKE 223
>gb|AAD31877.1|AF140353_1 (AF140353) 20S proteasome alpha 5 subunit [Trypanosoma brucei
brucei]
Length = 246
Score = 72.6 bits (175), Expect = 3e-12
Identities = 51/194 (26%), Positives = 94/194 (48%), Gaps = 13/194 (6%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T++GI+ D VI+AA+ + +V+ ++ KI+ I I +G V D +++
Sbjct: 32 KLGSTSLGIQTPDAVIIAAEKRVP-STLVDPSSVNKILEIDHHIGTVLSGMVADARILVD 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNIL-------NENKWF--PYLVQIIIGGYVDE- 113
EA+ ++FT+ PM+ + A ++ K P+ V ++I G VDE
Sbjct: 91 HARVEAQNHRFTYDEPMSVESCALATCDLSVQFGESGGRKKLMSRPFGVSLLIAG-VDEN 149
Query: 114 -PTIANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARD 172
P + DP G D A G G A + E Y +N+ +E+A+ L ++ ++
Sbjct: 150 GPQLWQTDPSGTYTRYDAQAIGGGAEAAQTVFSERYHRNMTVEEAENLTVQILRQVMEEK 209
Query: 173 VYTGSKKIQVVTIT 186
+ S +I +V ++
Sbjct: 210 LTKTSVEIAIVPVS 223
>gi|11424309 similar to proteasome (prosome, macropain) subunit, beta type, 3
(H. sapiens) [Homo sapiens]
Length = 205
Score = 72.6 bits (175), Expect = 3e-12
Identities = 51/187 (27%), Positives = 93/187 (49%), Gaps = 5/187 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
G + ++ K+ V +AAD + + + T + +KI P+ DR+ I AG DVQ +A+ L
Sbjct: 8 GGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRL 67
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY---VDEPTIANLDPL 122
+ Y+ GR + + ++++N+L E ++ PY + +I G +P I +LD +
Sbjct: 68 KFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLI 127
Query: 123 G-GLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G ++ DD+ +G+ + E + N+ + E +A+ A RD +G I
Sbjct: 128 GCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVI- 186
Query: 182 VVTITKD 188
V I KD
Sbjct: 187 VHIIEKD 193
>gb|AAB82570.1| (AF025791) 20S proteasome beta2 subunit [Drosophila melanogaster]
Length = 272
Score = 71.8 bits (173), Expect = 5e-12
Identities = 55/190 (28%), Positives = 92/190 (47%), Gaps = 5/190 (2%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VGI KDGVIL ADT+A+ +V N KI + I AG+ D +M
Sbjct: 37 KTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTD 96
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDP 121
++ ++ ++ R + A +L +L ++ ++ ++ G VD+ P I ++ P
Sbjct: 97 LISSQLELHRLQTDREVRVVAANTMLKQML--FRYQGHISAALVLGGVDKTGPHIYSIHP 154
Query: 122 LGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G Y GSG+ A+ + E ++ +L E+ K+L A D+ +GS I
Sbjct: 155 HGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDADPTGVFNDLGSGS-NID 213
Query: 182 VVTITKDGMK 191
+ I K ++
Sbjct: 214 LCVIRKGSVE 223
>gb|AAB82571.1| (AF025792) 20S proteasome beta2 subunit [Drosophila melanogaster]
Length = 272
Score = 71.8 bits (173), Expect = 5e-12
Identities = 55/190 (28%), Positives = 92/190 (47%), Gaps = 5/190 (2%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT VGI KDGVIL ADT+A+ +V N KI + I AG+ D +M
Sbjct: 37 KTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTD 96
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE--PTIANLDP 121
++ ++ ++ R + A +L +L ++ ++ ++ G VD+ P I ++ P
Sbjct: 97 LISSQLELHRLQTDREVRVVAANTMLKQML--FRYQGHISAALVLGGVDKTGPHIYSIHP 154
Query: 122 LGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
G Y GSG+ A+ + E ++ +L E+ K+L A D+ +GS I
Sbjct: 155 HGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDADPTGVFNDLGSGS-NID 213
Query: 182 VVTITKDGMK 191
+ I K ++
Sbjct: 214 LCVIRKGSVE 223
>gb|AAC45736.1| (U26422) proteasome beta-type subunit 2 [Rhodococcus erythropolis]
Length = 292
Score = 71.0 bits (171), Expect = 9e-12
Identities = 58/205 (28%), Positives = 99/205 (48%), Gaps = 18/205 (8%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GTT V I GV+LA D +A++ +++ + +++K+ D A AG+ G + R+
Sbjct: 59 GTTIVAISYAGGVLLAGDRRATMGNLIASRDVQKVYVTDDYSAAGIAGTAGIAIELVRLF 118
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPY----LVQIIIGGYVD--EPT---- 115
E +Y+ G P+T AN LS+++ N +V +++G +D +P+
Sbjct: 119 AVELEHYEKIEGVPLTFDGKANRLSSMVRGNLGAAMQGLAVVPLLVGYDLDAVDPSRAGR 178
Query: 116 IANLDPLGGLIFD--DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDV 173
I + D +GG + Y A GSG+ FA + L++ Y + + A A++A+ A D
Sbjct: 179 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKLYSPGIDEDTALRFAVEALYDAADDDS 238
Query: 174 YTGSKKI------QVVTITKDGMKE 192
TG + VTIT G E
Sbjct: 239 ATGGPDLTRGIYPTAVTITSAGAVE 263
>gb|AAD53037.1|AF115540_1 (AF115540) low molecular mass protein 2 [Oncorhynchus mykiss]
Length = 217
Score = 70.6 bits (170), Expect = 1e-11
Identities = 48/195 (24%), Positives = 93/195 (47%), Gaps = 15/195 (7%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLD-HMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
TGTT + + GVI+ +D++AS+ + V + I K+I + DRI AGS+ D Q + +
Sbjct: 15 TGTTILAVTFNGGVIIGSDSRASIGGYYVSSKTINKLIQVHDRIFCCIAGSLADAQAVTK 74
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-------PTI 116
+ + ++ P +A A++L + NK + + G++ P +
Sbjct: 75 AAKFQISFHSIQMESPPLVKAAASVLKELCYNNK------EELQAGFITAGWDRKKGPQV 128
Query: 117 ANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
+ G L+ +T GSG+ + + Y+ ++ E+ + A A+ A RD +G
Sbjct: 129 YTVALGGMLLSQPFTIGGSGSTYIYGYADAKYKPDMSKEECLQFATNALALAMGRDNVSG 188
Query: 177 SKKIQVVTITKDGMK 191
+V IT++G++
Sbjct: 189 G-VAHLVVITEEGVE 202
>sp|Q09841|PRCF_SCHPO PUTATIVE PROTEASOME COMPONENT PUP1 PRECURSOR (MACROPAIN SUBUNIT)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT)
>gi|2130339|pir||S62498 probable proteasome component
precursor - fission yeast (Schizosaccharomyces pombe)
>gi|1039345|emb|CAA91242.1| (Z64354) putative proteasome
component precursor [Schizosaccharomyces pombe]
Length = 267
Score = 69.5 bits (167), Expect = 3e-11
Identities = 48/175 (27%), Positives = 86/175 (48%), Gaps = 4/175 (2%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGTT VG+ KD ++L ADT+A+ ++ N +K+ I+ I AG+ D + + +
Sbjct: 34 TGTTIVGVIAKDCIVLGADTRATAGPIIADKNCKKLHLISPNIWCAGAGTAADTEFVTSM 93
Query: 65 LEAEARYYQ-FTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY-VDEPTIANLDPL 122
+ + + +T +P A+ L ++ +++GGY P + +
Sbjct: 94 ISSNIELHSLYTNRKPRVVTALTMLKQHLFRYQGHIG--AYLVLGGYDCKGPHLFTIAAH 151
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGS 177
G Y A GSG+ AI++LE Y+ +L +A EL +A++A D+ +GS
Sbjct: 152 GSSDKLPYVALGSGSLAAISVLETKYQPDLERHEAMELVKEAIEAGIFNDLGSGS 206
>dbj|BAA19146.1| (AB000540) proteasome component PUP1 precursor [Schizosaccharomyces
pombe]
Length = 258
Score = 69.5 bits (167), Expect = 3e-11
Identities = 48/175 (27%), Positives = 86/175 (48%), Gaps = 4/175 (2%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGTT VG+ KD ++L ADT+A+ ++ N +K+ I+ I AG+ D + + +
Sbjct: 25 TGTTIVGVIAKDCIVLGADTRATAGPIIADKNCKKLHLISPNIWCAGAGTAADTEFVTSM 84
Query: 65 LEAEARYYQ-FTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGY-VDEPTIANLDPL 122
+ + + +T +P A+ L ++ +++GGY P + +
Sbjct: 85 ISSNIELHSLYTNRKPRVVTALTMLKQHLFRYQGHIG--AYLVLGGYDCKGPHLFTIAAH 142
Query: 123 GGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGS 177
G Y A GSG+ AI++LE Y+ +L +A EL +A++A D+ +GS
Sbjct: 143 GSSDKLPYVALGSGSLAAISVLETKYQPDLERHEAMELVKEAIEAGIFNDLGSGS 197
>gb|AAD53519.1|AF155579_1 (AF155579) proteasome subunit beta 9A [Danio rerio]
Length = 218
Score = 69.5 bits (167), Expect = 3e-11
Identities = 52/193 (26%), Positives = 89/193 (45%), Gaps = 3/193 (1%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT + + GV++ +D++ S V + K+ P+ D+I +GS D Q IA
Sbjct: 17 KTGTTIIAVTFDGGVVIGSDSRVSAGESVVNRVMNKLSPLHDKIYCALSGSAADAQTIAE 76
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
I+ + + + A L+ NI + K +I+ G+ + L
Sbjct: 77 IVNYQLDVHSIEVEDDPLVCSAATLVKNISYKYK-EELSAHLIVAGWDKKGGGQVYATLS 135
Query: 124 GLIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
GL+ + GSG+ + ++ Y+KN+ + +E + A+ A RD +G V
Sbjct: 136 GLLTKQPFAIGGSGSFYINGFVDAEYKKNMTKRECQEFVVNALTLAMGRDGSSGG-VAYV 194
Query: 183 VTITKDGMKEEFV 195
VTI KDG +E+ V
Sbjct: 195 VTIDKDGTEEKCV 207
>pir||T48678 proteasome alpha-1 chain [validated] - Haloferax volcanii
>gi|5833206|gb|AAD53404.1|AF126260_1 (AF126260) alpha-1
subunit of 20S proteasome [Haloferax volcanii]
Length = 252
Score = 69.1 bits (166), Expect = 4e-11
Identities = 53/199 (26%), Positives = 95/199 (47%), Gaps = 10/199 (5%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K GT ++G+R +GV+LAAD + S ++E ++ KI D I I +AG V D + +
Sbjct: 34 KRGTASIGVRTPEGVVLAAD-KRSRSPLMEPTSVEKIHKADDHIGIASAGHVADARQLID 92
Query: 64 ILEAEARYYQFTWGRPM----TTRAMANLLSNILNENKWFPYLVQIIIGGYVD-EPTIAN 118
+++ + +G P+ T+ + + + P+ V ++IGG + P +
Sbjct: 93 FARHQSQVNRLRYGEPIGIETLTKEVTDHIQQYTQVGGARPFGVALLIGGVENGTPRLYE 152
Query: 119 LDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
DP G + G+ LEE +R +L +++ ELA++A+ A D T
Sbjct: 153 TDPSGTPYEWKAVSIGADRGDHQEHLEENFRDDLTLDEGIELALEAI--ASTSDEGTAPD 210
Query: 179 KIQVVTITKDGMKEEFVTL 197
+ V T++ + E FV L
Sbjct: 211 GVDVATVSAE--TERFVEL 227
>dbj|BAA96839.1| (AB026568) beta 7 subunit of 20S proteasome [Oryza sativa]
Length = 256
Score = 69.1 bits (166), Expect = 4e-11
Identities = 52/194 (26%), Positives = 94/194 (47%), Gaps = 11/194 (5%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TG++ + ++ KDGVI+A+DT AS + ++ +I + I +G D Q I R
Sbjct: 36 TGSSIIALKYKDGVIMASDTGASYGSTLRYKSVERIKAVGKHSLIGASGEFSDFQEILRY 95
Query: 65 LEAEARYYQFTW--GRPMTTRAMANLLSNIL--NENKWFPYLVQIIIGGYV-----DEPT 115
L+ E W G + + + + L+ ++ NK+ P ++IGG +E
Sbjct: 96 LD-ELTLSDHMWDDGNSLGPKEVHSYLTRVMYNRRNKFDPLWNSLVIGGVKKGPKGEEKY 154
Query: 116 IANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYT 175
+ ++ +G +++ ATG G AI IL +R+++ E+A +L K + RD +
Sbjct: 155 LGMVNMIGTHFEENHIATGFGNHMAIPILRTEWREDMTFEEAVKLVEKCLLVLLYRD-RS 213
Query: 176 GSKKIQVVTITKDG 189
K Q+ IT +G
Sbjct: 214 SINKFQIAKITTEG 227
>emb|CAA74026.1| (Y13692) multicatalytic endopeptidase complex, proteasome
component, beta subunit [Arabidopsis thaliana]
>gi|3421111|gb|AAC32070.1| (AF043534) 20S proteasome
beta subunit PBD1 [Arabidopsis thaliana]
Length = 204
Score = 68.7 bits (165), Expect = 5e-11
Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 10/180 (5%)
Query: 19 ILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILEAEARYYQFTWGR 78
I+AADT A ++ N KI+ + + +G GD ++ Y+F G
Sbjct: 14 IVAADTSAVHSILLHKNNEDKIMVLDSHKLVAASGEPGDRVQFTEYVQKNVSLYKFRNGI 73
Query: 79 PMTTRAMANL----LSNILNENKWFPYLVQIIIGGYVDE--PTIANLDPLGGLIFDDYTA 132
P+TT A AN L+ L +N PY V I++ GY DE ++ +D + L D A
Sbjct: 74 PLTTAAAANFTRGELATALRKN---PYSVNILMAGYDDESGASLYYIDYIATLHKVDKGA 130
Query: 133 TGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVVTITKDGMKE 192
G G+ F+++ ++ YR ++ +E+A EL K + +R + + + KDG ++
Sbjct: 131 FGYGSYFSLSTMDRHYRSDMSVEEAIELVDKCILEIRSR-LVVAPPNFVIKIVDKDGARD 189
>pdb|1G65|H Chain H, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513434|pdb|1G65|V Chain V, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors >gi|11513999|pdb|1G0U|H Chain H, A Gated
Channel Into The Proteasome Core Particle
>gi|11514013|pdb|1G0U|V Chain V, A Gated Channel Into
The Proteasome Core Particle >gi|3114277|pdb|1RYP|I
Chain I, Crystal Structure Of The 20s Proteasome From
Yeast At 2.4 Angstroms Resolution >gi|3114291|pdb|1RYP|W
Chain W, Crystal Structure Of The 20s Proteasome From
Yeast At 2.4 Angstroms Resolution
Length = 222
Score = 68.7 bits (165), Expect = 5e-11
Identities = 55/194 (28%), Positives = 99/194 (50%), Gaps = 23/194 (11%)
Query: 7 TTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILE 66
TT VG++ +GV++AADT+++ +V N K+ I+ +I AG+ D + + +++
Sbjct: 1 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 60
Query: 67 AEARYYQ-FTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLGGL 125
+ + +T P A+ L ++ F Y Q IG Y+ +A +DP G
Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHL------FKY--QGHIGAYL---IVAGVDPTGSH 109
Query: 126 IFD----------DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYT 175
+F Y + GSG+ A+A+LE ++++L E+A +LA A++A D+ +
Sbjct: 110 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGS 169
Query: 176 GSK-KIQVVTITKD 188
GS + V+ I KD
Sbjct: 170 GSNVDVCVMEIGKD 183
>gb|AAF58077.1| (AE003808) CG8392 gene product [Drosophila melanogaster]
Length = 224
Score = 68.7 bits (165), Expect = 5e-11
Identities = 55/190 (28%), Positives = 88/190 (45%), Gaps = 6/190 (3%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGTT + + GV++ AD++ S V K+ ITD++ +GS D Q IA I
Sbjct: 14 TGTTIMAVEFDGGVVIGADSRTSSGAYVANRVTDKLTRITDKVYCCRSGSAADTQAIADI 73
Query: 65 LEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANL--DPL 122
+ Y++ + A+ N + L II+ G+ DE + PL
Sbjct: 74 VAYSLNYHENQTNKDALVFEAASEFRNYCYSYR-ESLLAGIIVAGW-DEQRGGQVYSIPL 131
Query: 123 GGLIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
GG++ + T GSG+ F + E YR N+ +E KAV+ A D +G ++
Sbjct: 132 GGMLTRESCTIGGSGSSFIYGFVREHYRPNMALEDCVTFVKKAVQHAIYHDGSSGG-VVR 190
Query: 182 VVTITKDGMK 191
+ ITKDG++
Sbjct: 191 IGIITKDGIE 200
>emb|CAB86711.1| (AL163505) 20S proteasome alpha 5 subunit [Leishmania major]
Length = 244
Score = 68.7 bits (165), Expect = 5e-11
Identities = 54/204 (26%), Positives = 96/204 (46%), Gaps = 15/204 (7%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G+T++GIR GV+LAA+ + +V + ++ KI+ I IA +G V D +++
Sbjct: 32 KLGSTSLGIRTPKGVVLAAEKRVPSTLVVPS-SMSKIMEIDSHIAAVMSGMVADARILVE 90
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNIL-------NENKWF--PYLVQIIIGGYVDE- 113
E++ ++FT+ PM+ + ++ + K P+ V ++I G VDE
Sbjct: 91 HARVESQNHRFTYNEPMSVESCTLATCDLSIQFGESGGKRKLMSRPFGVSLLIAG-VDEK 149
Query: 114 -PTIANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARD 172
P + DP G D A G G A ++ E Y +N+ +E+ + LA+ +K +
Sbjct: 150 GPQLWQTDPSGTHTRYDAQAIGGGAEAAQSVFTERYHRNMTLEEGETLAVDILKQ--VME 207
Query: 173 VYTGSKKIQVVTITKDGMKEEFVT 196
+ I+V + D K T
Sbjct: 208 DQLSPENIEVAVVRADDGKLHMYT 231
>gi|6322459 Subunit of 20S proteasome; Pre3p [Saccharomyces cerevisiae]
>gi|1172606|sp|P38624|PRCD_YEAST PROTEASOME COMPONENT
PRE3 PRECURSOR (MACROPAIN SUBUNIT PRE3) (PROTEINASE YSCE
SUBUNIT PRE3) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT PRE3) >gi|2118153|pir||S61337 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain PRE3 - yeast
(Saccharomyces cerevisiae) >gi|2131077|emb|CAA89290.1|
(Z49276) ORF YJL001w [Saccharomyces cerevisiae]
Length = 215
Score = 68.3 bits (164), Expect = 6e-11
Identities = 53/188 (28%), Positives = 89/188 (47%), Gaps = 5/188 (2%)
Query: 6 GTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARIL 65
GT+ + + KDGVIL AD++ + + K+ + D+I +GS D Q IA I+
Sbjct: 19 GTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIV 78
Query: 66 EAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE-PTIANLDPLGG 124
+ Y +G P T A A++ + ENK II+ GY D+ PLGG
Sbjct: 79 QYHLELYTSQYGTPSTETA-ASVFKELCYENK-DNLTAGIIVAGYDDKNKGEVYTIPLGG 136
Query: 125 LIFD-DYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQVV 183
+ Y GSG+ F ++ +R+N+ E+ + ++ A D +G I++V
Sbjct: 137 SVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGG-VIRMV 195
Query: 184 TITKDGMK 191
+T G++
Sbjct: 196 VLTAAGVE 203
>dbj|BAA19761.1| (D87690) proteasome subunit Y [Lampetra japonica]
Length = 231
Score = 67.9 bits (163), Expect = 8e-11
Identities = 50/195 (25%), Positives = 89/195 (45%), Gaps = 6/195 (3%)
Query: 5 TGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARI 64
TGTT + + DGV+ AD++ + V K+ P+ DRI +GS D Q IA +
Sbjct: 30 TGTTIMAVEFADGVVFGADSRTTSGSYVANRVTDKLTPVHDRIFCCRSGSAADTQAIADV 89
Query: 65 LEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANL--DPL 122
+ + ++ ANL + + + II+ G+ D+ + PL
Sbjct: 90 VNYQLGFHSIEMEEMPLVHTAANLFKDYCYRYR-EELMAGIIVAGW-DKRKGGQVYTVPL 147
Query: 123 GG-LIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQ 181
GG L+ ++ GSG+ + ++ Y+ + E+ E KA+ A +RD +G I+
Sbjct: 148 GGMLVRQPFSVGGSGSTYIYGFVDSNYKTGMTKEECMEFTAKALSLAMSRDGSSGG-VIR 206
Query: 182 VVTITKDGMKEEFVT 196
+ IT G++ +T
Sbjct: 207 MAAITAGGVERRVLT 221
>dbj|BAA19766.1| (D89724) LMP2 [Oryzias latipes]
Length = 213
Score = 67.9 bits (163), Expect = 8e-11
Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 3/193 (1%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
KTGTT + I GV+L +D++ S V + K+ P+ DRI +GS D Q IA
Sbjct: 12 KTGTTIIAIEFNGGVVLGSDSRVSAGDSVVNRVMNKLSPLHDRIYCALSGSAADAQTIAE 71
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDEPTIANLDPLG 123
++ + + R+ A L+ NI + K +I+ G+ LG
Sbjct: 72 MVNYQLDVHSLEIDEDPQVRSAATLVKNISYKYK-EELSAHLIVAGWDRRDGGQVFATLG 130
Query: 124 GLIF-DDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSKKIQV 182
GL+ + GSG+ + ++ YR+ + E+ ++ + + A RD +G +
Sbjct: 131 GLLTRQPFAIGGSGSSYVYGFVDAEYRRGMTKEECQKFVVNTLALAMNRDGSSGG-VAYI 189
Query: 183 VTITKDGMKEEFV 195
VTI + E+ +
Sbjct: 190 VTIDEHSTDEKVI 202
>pir||T23336 hypothetical protein K05C4.1 - Caenorhabditis elegans
>gi|3924797|emb|CAB04567.1| (Z81564) contains similarity
to Pfam domain: PF00227 (Proteasome A-type and B-type),
Score=135.9, E-value=2.4e-37, N=1~cDNA EST EMBL:T00391
comes from this gene~cDNA EST EMBL:T00392 comes from
this gene~cDNA EST yk633d10.3 comes from this gene~cDNA
EST>
Length = 284
Score = 67.9 bits (163), Expect = 8e-11
Identities = 50/184 (27%), Positives = 85/184 (46%), Gaps = 8/184 (4%)
Query: 1 MNRKTGTTTVGIRV-------KDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAG 53
M + GTTT+ K G+I+A D++AS + + ++ KI+ I DR+ T AG
Sbjct: 59 MQFRKGTTTLAFVYEPATPADKGGIIVAVDSRASSGEYISSKSVMKILDIGDRMVATMAG 118
Query: 54 SVGDVQMIARILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWFPYLVQIIIGGYVDE 113
D Q RI+ Y+ +T A + +N L + V ++ GY +
Sbjct: 119 GAADCQFWTRIVAKYCTLYELREKTSITVSAASKYFANTLYGYRGQGLSVGSMVAGYDKK 178
Query: 114 -PTIANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARD 172
P I +D G + GSG+ A IL+ Y+ + ++A++L ++A+ A RD
Sbjct: 179 GPQIFKVDSEGDRCQLKVCSVGSGSLNAYGILDNHYKPKMTDDEARKLGLRAIMHATYRD 238
Query: 173 VYTG 176
+G
Sbjct: 239 SGSG 242
>dbj|BAA76428.1| (AB025000) multicatalytic endopeptidase complex [Cicer arietinum]
Length = 249
Score = 67.9 bits (163), Expect = 8e-11
Identities = 52/192 (27%), Positives = 90/192 (46%), Gaps = 13/192 (6%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
+ G VG+R D V+L + +++ + +T ++RKI+ + D IA+ AG D +++
Sbjct: 28 RKGNAAVGVRGTDNVVLGVEKKSTAK-LQDTRSVRKIVNLDDHIALACAGLKADARVLIN 86
Query: 64 ILEAEARYYQFTWGRPMT----TRAMANLLSNILNENKWFPYLVQIIIGG---YVDEPTI 116
E + ++ T P+T TR +A L P+ + +I G Y P++
Sbjct: 87 RARVECQSHRLTVEDPVTVEYITRYIAGLQQKYTQSGGVRPFGLSTLIVGFDPYTGSPSL 146
Query: 117 ANLDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTG 176
DP G ATG + LE+ +++ G E K LAI+A+ V +G
Sbjct: 147 YQTDPSGTFSAWKANATGRNSNSIREFLEKNFKETSGQETVK-LAIRALLEV----VESG 201
Query: 177 SKKIQVVTITKD 188
K I+V +TK+
Sbjct: 202 GKNIEVAVMTKE 213
>pir||T48679 proteasome alpha-2 chain [validated] - Haloferax volcanii
>gi|5833208|gb|AAD53405.1|AF126261_1 (AF126261) alpha-2
subunit of 20S proteasome [Haloferax volcanii]
Length = 249
Score = 67.9 bits (163), Expect = 8e-11
Identities = 50/191 (26%), Positives = 90/191 (46%), Gaps = 9/191 (4%)
Query: 4 KTGTTTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIAR 63
K G +G+R DGV+LAA +++ ++E +I K+ + D + TAG V D + +
Sbjct: 33 KRGAPVLGVRTADGVVLAA-LRSTPSELMEAESIEKLHKLDDALGAATAGHVADARKLVD 91
Query: 64 ILEAEARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVD-EPTIAN 118
A+ +G P+ + +++ + E+ PY ++IGG + +
Sbjct: 92 FARTTAQREHLRYGEPIGVETLTKTITDNIQESTQSGGTRPYGASLLIGGVENGSGRLFA 151
Query: 119 LDPLGGLIFDDYTATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVKAAGARDVYTGSK 178
DP G A G A LE+GY ++L +E LA++A+ AA D S
Sbjct: 152 TDPSGTPQEWKAVAIGGHREDVQAALEDGYAEDLSLEDGLALAVEALVAA---DEEIESD 208
Query: 179 KIQVVTITKDG 189
++ +VT+++ G
Sbjct: 209 ELNLVTVSEAG 219
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.137 0.384
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66321183
Number of Sequences: 2977
Number of extensions: 2641204
Number of successful extensions: 6890
Number of sequences better than 1.0e-10: 155
Number of HSP's better than 0.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 125
Number of HSP's that attempted gapping in prelim test: 6707
Number of HSP's gapped (non-prelim): 156
length of query: 197
length of database: 189,106,746
effective HSP length: 56
effective length of query: 141
effective length of database: 155,591,474
effective search space: 21938397834
effective search space used: 21938397834
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 163 (67.9 bits)