BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2202 (PAB2202) DE:OLIGOSACCHARYL TRANSFERASE
(976 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75212 oligosaccharyl transferase PAB2202 - Pyrococcus abys... 1966 0.0
pir||C71248 hypothetical protein PH0242 - Pyrococcus horikoshii ... 1559 0.0
pir||B75059 probable transmembrane oligosaccharyl transferase PA... 120 1e-25
pir||D71072 hypothetical protein PH1271 - Pyrococcus horikoshii ... 118 2e-25
pir||C75100 hypothetical protein PAB1586 - Pyrococcus abyssi (st... 105 3e-21
gi|4504787 integral membrane protein 1; integral transmembrane p... 87 1e-15
gi|6680498 intergral membrane protein 1 [Mus musculus] >gi|11744... 82 4e-14
pir||S70029 probable transmembrane protein TMC - human 80 9e-14
gb|AAK41316.1| Oligosaccharyl transferase STT3 subunit (B5) (int... 72 3e-11
>pir||E75212 oligosaccharyl transferase PAB2202 - Pyrococcus abyssi (strain
Orsay) >gi|5457657|emb|CAB49148.1| (AJ248283)
OLIGOSACCHARYL TRANSFERASE [Pyrococcus abyssi]
Length = 976
Score = 1966 bits (5037), Expect = 0.0
Identities = 976/976 (100%), Positives = 976/976 (100%)
Query: 1 MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF 60
MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF
Sbjct: 1 MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF 60
Query: 61 YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW 120
YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW
Sbjct: 61 YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW 120
Query: 121 PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS 180
PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS
Sbjct: 121 PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS 180
Query: 181 LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK 240
LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK
Sbjct: 181 LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK 240
Query: 241 IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF 300
IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF
Sbjct: 241 IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF 300
Query: 301 LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI 360
LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI
Sbjct: 301 LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI 360
Query: 361 KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV 420
KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV
Sbjct: 361 KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV 420
Query: 421 RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN 480
RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN
Sbjct: 421 RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN 480
Query: 481 AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD 540
AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD
Sbjct: 481 AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD 540
Query: 541 RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR 600
RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR
Sbjct: 541 RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR 600
Query: 601 GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI 660
GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI
Sbjct: 601 GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI 660
Query: 661 PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP 720
PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP
Sbjct: 661 PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP 720
Query: 721 VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY 780
VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY
Sbjct: 721 VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY 780
Query: 781 AIGNKTEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNGEI 840
AIGNKTEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNGEI
Sbjct: 781 AIGNKTEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNGEI 840
Query: 841 ANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMDTF 900
ANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMDTF
Sbjct: 841 ANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMDTF 900
Query: 901 FITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAEKE 960
FITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAEKE
Sbjct: 901 FITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAEKE 960
Query: 961 YVMAEVRASAPHHGSE 976
YVMAEVRASAPHHGSE
Sbjct: 961 YVMAEVRASAPHHGSE 976
>pir||C71248 hypothetical protein PH0242 - Pyrococcus horikoshii
>gi|3256631|dbj|BAA29314.1| (AP000001) 976aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 976
Score = 1559 bits (3991), Expect = 0.0
Identities = 748/978 (76%), Positives = 851/978 (86%), Gaps = 4/978 (0%)
Query: 1 MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF 60
MVK+KVK+ ++ K E E +S Y LLK++LIP+ V GF IYA+YLRHLTAGKYFPDPDTF
Sbjct: 1 MVKSKVKKVEKGK-EGEEKRSTYVLLKKVLIPILVFGFAIYAFYLRHLTAGKYFPDPDTF 59
Query: 61 YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW 120
YHFEIYKLVLKEGLP+YYPM++APFGSLIGEPLGLY+LPA FYKVVS+FGYNE QAFL+W
Sbjct: 60 YHFEIYKLVLKEGLPRYYPMSDAPFGSLIGEPLGLYLLPAAFYKVVSLFGYNELQAFLLW 119
Query: 121 PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS 180
PPFVGFLGVIAVYLLGRKVLNEW GLW AV+L+VSTANFSRTFSGNARGDGPFM LF+F+
Sbjct: 120 PPFVGFLGVIAVYLLGRKVLNEWTGLWGAVVLTVSTANFSRTFSGNARGDGPFMALFIFA 179
Query: 181 LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK 240
VAMLYYLKE++ +K ++G +FVLL ISLGAWNGSPFGLMVL+GFAS QTI LFIFGK
Sbjct: 180 SVAMLYYLKESNKTRKIIYGTLFVLLTVISLGAWNGSPFGLMVLLGFASLQTIILFIFGK 239
Query: 241 IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF 300
++ELKKFVKEFYPAYLAILA GY LT PGI KIGGFI+FAFEVFLGL+ L+ IMLYGG++
Sbjct: 240 LEELKKFVKEFYPAYLAILAFGYALTFPGIVKIGGFIRFAFEVFLGLIFLLVIMLYGGRY 299
Query: 301 LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI 360
LNYSDKKHRF VV +IVLLGF GAYAYVGPKLFRLMGGAYQSTQVY+TVQELAKTT+ D+
Sbjct: 300 LNYSDKKHRFLVVTIIVLLGFGGAYAYVGPKLFRLMGGAYQSTQVYETVQELAKTTIGDV 359
Query: 361 KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV 420
K YYGVE NGL+FFLSIPG LI+L YL L KK++S NE + +LVFY MSLYLL LAV
Sbjct: 360 KAYYGVESGNGLIFFLSIPGLLILLTKYLYDLFKKAKSDNETLFALVFYTMSLYLLYLAV 419
Query: 421 RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN 480
RFLFLASYA+ALF GIF GF+M+VIEKMKEN+GIKAALGI +++MIL++P H PV+AR+
Sbjct: 420 RFLFLASYAVALFFGIFIGFSMDVIEKMKENIGIKAALGIVLSLMILVIPFVHAPVLARS 479
Query: 481 AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD 540
A+ALK +EIE TGWEQ LKWL NTSKYATATSWWDYGYWIESSLLG+RRASADGGHARD
Sbjct: 480 ARALKNTEIEVTGWEQALKWLRSNTSKYATATSWWDYGYWIESSLLGNRRASADGGHARD 539
Query: 541 RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR 600
RDHILALFLARDGN+SEVDFESWELNYFIIYLNDWAKFNAISYLGGAITR+EYNGDE GR
Sbjct: 540 RDHILALFLARDGNISEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRKEYNGDENGR 599
Query: 601 GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI 660
G+VTTIL Q +G +YVNPYA I ++V+Q N T ++ VN+ G+ ECSPI ++ PGN KI
Sbjct: 600 GRVTTILLTQAAGNVYVNPYARIVIKVIQQNKTRRIAVNI-GQLECSPILSVAFPGNIKI 658
Query: 661 PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP 720
G+GRCSDGSPFPYV+YL P+ G++ YYKVATSNF+KLAF IP S YS F EKL+SNF+P
Sbjct: 659 KGSGRCSDGSPFPYVVYLTPSLGVLAYYKVATSNFVKLAFGIPTSSYSEFAEKLFSNFIP 718
Query: 721 VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY 780
VY YG+VIVYEFRPFAIY+IE+ INGTW+ V L+PGKH L+LYISAFGRDI+NATLYVY
Sbjct: 719 VYQYGSVIVYEFRPFAIYKIEDFINGTWREVGKLSPGKHTLRLYISAFGRDIKNATLYVY 778
Query: 781 AI-GNK-TEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNG 838
A+ G K ++IK+GEI+YMNHL E PIIVNVTLP A+KYR +L QKGPVGVLTGP ++NG
Sbjct: 779 ALNGTKIIKRIKVGEIKYMNHLEEYPIIVNVTLPTAQKYRFILAQKGPVGVLTGPVRVNG 838
Query: 839 EIANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMD 898
+I NP I REGE G L LKVGVDK+YTADLYLRATFIYLVRK GKSN+DY+A+FEPHMD
Sbjct: 839 KITNPAYIMREGESGRLELKVGVDKEYTADLYLRATFIYLVRKGGKSNEDYDASFEPHMD 898
Query: 899 TFFITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAE 958
TFFITKLK GIKL G+N + MP ISSYKEKLEKE+GDKLIIRGIRVEPVFI E
Sbjct: 899 TFFITKLKEGIKLRPGENEIVVNAEMPKNAISSYKEKLEKEHGDKLIIRGIRVEPVFIVE 958
Query: 959 KEYVMAEVRASAPHHGSE 976
KEY M EV ASAPHH SE
Sbjct: 959 KEYTMIEVSASAPHHSSE 976
>pir||B75059 probable transmembrane oligosaccharyl transferase PAB0974 -
Pyrococcus abyssi (strain Orsay)
>gi|5458880|emb|CAB50367.1| (AJ248287) TRANSMEMBRANE
OLIGOSACCHARYL TRANSFERASE, PUTATIVE. [Pyrococcus
abyssi]
Length = 766
Score = 120 bits (297), Expect = 1e-25
Identities = 151/623 (24%), Positives = 274/623 (43%), Gaps = 85/623 (13%)
Query: 28 RILIPLAV-IGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLP-KYYPMAEAPF 85
+I +P+ V +G + LR KY D ++H + LK G ++ +A P+
Sbjct: 10 KIALPIVVLVGVTLRVIPLRF----KYLLGYDPYFHLAYIEESLKAGKWFNFFTIANGPW 65
Query: 86 GSLIGE--PLGLYILPAIFYKVVSVFGYNEFQAFLMWPPFVGFLGVIAVYLLGRKVLNEW 143
G I PLGL++ PA Y+ + VFG + F + P G L ++ Y+ K+ +
Sbjct: 66 GFQIKSFHPLGLWMTPAYIYRFLKVFGISVQTVFKITPVIFGTLTIVFFYISLLKLYGKE 125
Query: 144 AGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIKKKSLWGAVF 203
+A++ L++S + R+ + RGD + + +L + Y L+ ++ + V
Sbjct: 126 KAFFASIFLALSFGHIFRSMANYYRGDNYMLFWYSLALAGIAYALRTKGYRRLVFY-LVP 184
Query: 204 VLLASISLGAWNGSPFGLMVLIGF-ASFQTIALFIFGKIKE-LKKFVKEFYPAYLAILA- 260
L + IS W + + L V + F I F+ K + L F+ A+ AI+A
Sbjct: 185 TLASGISSVFWQ-AYYPLFVFLSLNGVFLAIGSFLLDKKRNFLDSFIIILSTAFGAIIAN 243
Query: 261 -----IGYGLTIPG----IAKIG----------GFIKFAFEVFLGLVLLVTIMLYGGKFL 301
GYG+ ++K+G FI + V + L LL+ I+L+ +F+
Sbjct: 244 YLGEKFGYGMLGYNRQHIVSKLGIKLGKIRDAYLFIHLHYLVPISLGLLI-ILLFLSRFV 302
Query: 302 NYSDKKHRFAVVAVIVLLGFAGAYAYV--GPKLFRLMG--GAYQSTQVYQTVQELAKTTL 357
K + A V +++ LG + P L L+G ++ST + +T T
Sbjct: 303 -----KSKRAKVGIVIGLGTVSILIILLKFPALRGLLGIFDMFKSTPIMET----RPTNF 353
Query: 358 SDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLS 417
D+ + + +F L + +L +K ++ + ++L L+ + SLY+L
Sbjct: 354 HDLWKAFSIS-----IFLLPL--------FFLRFHPEKVKTEDFFLLGLI--VPSLYMLL 398
Query: 418 LAVRFLFLASYAIALFSGI--FAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGP 475
RF+F+ S A+A +GI G+++ VI++ K + AL ++++++ I +G
Sbjct: 399 AWARFVFVGSLAVATMAGIGLVEGYSL-VIQRRKSGKASRVAL-----ILLILLLIVNGA 452
Query: 476 VIARNAKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADG 535
+N L + + WE L WL N+++ +WWDYG WI + R +
Sbjct: 453 FTLKN--CLSMRPLINKEWENALIWLKNNSNENDVILAWWDYGAWITY----YSRRAPVA 506
Query: 536 GHARDRDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNG 595
A + D L AR+ + S ++Y I+ D+ KF++I T +G
Sbjct: 507 EIAPNPDVALYYLGARNRDW----IMSLGVDYVIVSYYDFLKFSSI-----VRTASAQSG 557
Query: 596 DETGRGQVTTILPLQGS-GGIYV 617
+ +LPL S GGI +
Sbjct: 558 YNLIKRYWIAVLPLTSSYGGILI 580
>pir||D71072 hypothetical protein PH1271 - Pyrococcus horikoshii
>gi|3257691|dbj|BAA30374.1| (AP000005) 758aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 758
Score = 118 bits (294), Expect = 2e-25
Identities = 148/601 (24%), Positives = 250/601 (40%), Gaps = 83/601 (13%)
Query: 52 KYFPDPDTFYHFEIYKLVLKEGL-PKYYPMAEAPFGSLIG--EPLGLYILPAIFYKVVSV 108
KY D ++H + V K G + A P+G + PLGL++ P YK++ V
Sbjct: 25 KYLLGYDPYFHLAYIEEVNKVGKWINFLTFAGGPWGYQVKLFHPLGLWMTPLYLYKLLKV 84
Query: 109 FGYNEFQAFLMWPPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNAR 168
FG + F + P G L VI +YL K+ +E + L++S + R+ + R
Sbjct: 85 FGVSLTTTFKITPVIFGVLTVIFLYLSLLKLYDEKRAFFGGFFLAISYGHVFRSMANYYR 144
Query: 169 GDGPFMTLFLFSL--VAMLYYLKENDIK-KKSLWGAVFVLLASISLGAWNGSPFGLMVLI 225
GD + + +L +++ +K+ K K+ ++ + VL + S W L+
Sbjct: 145 GDNYMLFWYSVALLGISLALGIKKGKWKYKRLIFYTLPVLASGFSAIFWQAYYPIFAFLL 204
Query: 226 GFASFQTIALFIFGKIKELKKFVKEFYPAYLAILAIGYGLTIPG-IAKIGGFIKFAFEVF 284
A + FI K K L + + IL+ +G+ + + I G+ + +
Sbjct: 205 SNALLLAVGAFILKKDKYL-------LDSIILILSTAFGVLLANYLGGIFGYGMLGYAKW 257
Query: 285 LGLVLLVTIMLYGGKFLNYSDKKH-------RFAVVAVIVLLG-----------FAGAYA 326
LG + + L G + H + V V++LLG F G +
Sbjct: 258 LGKSVAKKLGLEFGYLKDVYLILHLKYLVPISLSFVLVLILLGFLTKDIRIRSLFLGIAS 317
Query: 327 YVGP----KLFRLMGGAYQSTQVYQ--TVQELAKTTLSDIKLYYGVEGNNGLVFFLSIPG 380
++G K F + +++ + E T+ D+ + L FFL+ P
Sbjct: 318 FIGIIILFKRFEALKELSTGFGIFKEAPILETQPTSFKDLWAAF------SLSFFLT-PL 370
Query: 381 FLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAVRFLFLASYAIALFSGIFAGF 440
F I + + E L+L I S+Y+L RFLF+ S AIA+ SGI
Sbjct: 371 FFI----------RFKKPRVEDFLTLGLIIPSVYMLKTWTRFLFIGSMAIAIMSGI---G 417
Query: 441 TMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARNAKALKVSEIETTGWEQVLKW 500
+E+ E +K + K AL I ++++ + G + + WE+ LKW
Sbjct: 418 IVELYEAIKPRLNGKKALATGIITLVILPGVIAG---LSFKEVCSLHPEMNEAWERALKW 474
Query: 501 LNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARDRDHILALFLARDGNVSEVDF 560
L N+++ +WWD+G++I + R A GG + +AL+L N
Sbjct: 475 LKNNSNENDVILAWWDWGHFI--TYYARRSPIAQGGPSVG----VALYLLGKLN------ 522
Query: 561 ESWELN----YFIIYLNDWAKFNAISYLGGAITRREYNGDETGRGQVTTILPLQGSGGIY 616
E+W +N Y I+ D+ KF AI L A + YN RG +LPL+ S G
Sbjct: 523 ENWAINLGVDYVIVSYYDFLKFGAI--LSTANLSKRYN----IRGYGLVVLPLRASTGAL 576
Query: 617 V 617
+
Sbjct: 577 I 577
>pir||C75100 hypothetical protein PAB1586 - Pyrococcus abyssi (strain Orsay)
>gi|5458616|emb|CAB50104.1| (AJ248286) hypothetical
protein [Pyrococcus abyssi]
Length = 765
Score = 105 bits (259), Expect = 3e-21
Identities = 149/633 (23%), Positives = 257/633 (40%), Gaps = 96/633 (15%)
Query: 22 LYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEG-LPKYYPM 80
L P R+ +P+ ++ + +Y KY D + H + LK G ++ +
Sbjct: 6 LNPFKPRVALPIIIV---VSLFYRLLTFRFKYLLGYDPYLHLAYIEEALKAGEWFNFFTL 62
Query: 81 AEAPFGSLIGE--PLGLYILPAIFYKVVSVFGYNEFQAFLMWPPFVGFLGVIAVYLLGRK 138
A+AP+G + + PLGL+++PA +K+ ++ Y AF + P G L V+ YL K
Sbjct: 63 AKAPWGMQMRKFHPLGLWMIPAYIHKIFNIPLYT---AFKITPVIFGVLTVVFTYLALLK 119
Query: 139 VLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIKKKSL 198
+ E +A++ L VS + R+ + RGD + + + + + L E K+
Sbjct: 120 LYGERKAFYASLFLGVSYGHVFRSMANYYRGDNYMLFWYSLAFLGIALALGE----KRRS 175
Query: 199 WG---AVFVLLASISLGA----WNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEF 251
W +F L+ I G W + L+G A + F+ ++E K +
Sbjct: 176 WRYRRLIFYLIPGIGSGLASIFWQAYYPIFIFLLGNALLLSFGAFL---LREDKYILDGL 232
Query: 252 YPAYLAILA----------IGYGLT--IPGIAKI-------------GGFIKFAFEVFLG 286
A L +L GYG+ G+ K F+ + +
Sbjct: 233 LLASLTVLGAFMANYLGGKFGYGMFGYDHGLGKTVAEKLSLELSTIKDAFLLVYLKYLVP 292
Query: 287 LVLL-VTIMLYGGKFLNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQV 345
LV+L + I+L FL K R + I+LLG G L L G +V
Sbjct: 293 LVVLGIVILLVVSYFLK--SLKARAVLSTFIILLGLLIVLLKFGSLLKDLSTGFGMFKEV 350
Query: 346 YQTVQELAKTTLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLS 405
+ E SD+ + + +FFL ++ + + L
Sbjct: 351 --PIAETVPPKFSDLWAAFALSLFLSPLFFLEF---------------RRPKVQDFMFLG 393
Query: 406 LVFYIMSLYLLSLAVRFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVM 465
L+ I SLY+ RFLF+ S A+ L +GI E I ++ L +A+ ++
Sbjct: 394 LI--IPSLYMFLTWTRFLFIGSLAVTLMAGIGLISAYERI--------LRKGLALALILL 443
Query: 466 ILMVPITHGPVIARNAKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSL 525
+++ + G + N A K + W L+WL N+++ +WWDYG WI +
Sbjct: 444 VILPGVNAG--VGFNYVA-KQKPLINDYWVNALRWLRSNSNENDIVLAWWDYGQWI--TY 498
Query: 526 LGHRRASADGGHARDRDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLG 585
R A G + +AL+L G ++ ES ++Y I+ D+ KF AI +
Sbjct: 499 YARRAPIAQGSPSIG----VALYLL--GKLNYRWAESLGVDYVIVSYYDFLKFPAI--VA 550
Query: 586 GAITRREYNGDETGRGQVTTILPL-QGSGGIYV 617
A +YN G ++PL + +G ++V
Sbjct: 551 TANMHPKYN----LTGYALVVVPLVERAGDVFV 579
>gi|4504787 integral membrane protein 1; integral transmembrane protein 1;
Transmembrane conserved gene [Homo sapiens]
>gi|1174469|sp|P46977|STT3_HUMAN OLIGOSACCHARYL
TRANSFERASE STT3 SUBUNIT HOMOLOG (B5) (INTEGRAL MEMBRANE
PROTEIN 1) (TMC) >gi|624704|gb|AAB05994.1| (L38961)
putative transmembrane protein precursor [Homo sapiens]
>gi|1588286|prf||2208301B integral membrane protein
[Homo sapiens]
Length = 705
Score = 86.6 bits (211), Expect = 1e-15
Identities = 125/553 (22%), Positives = 226/553 (40%), Gaps = 93/553 (16%)
Query: 25 LLKRILIPLA-VIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPKYY----P 79
LLK +++ +A V+ F + + + + DP ++++ + + +EG K++
Sbjct: 17 LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDP--YFNYRTTRFLAEEGFYKFHNWFDD 74
Query: 80 MAEAPFGSLIGEPL--GLYILPAIFYKVVSVFGYN---EFQAFLMWPPFVGFLGVIAVYL 134
A P G +IG + GL I A Y V+ F + P F F ++ YL
Sbjct: 75 RAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTSIVT-YL 133
Query: 135 LGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIK 194
L +++ + AGL AA +++V SR+ +G+ +G + +F ++ + YY+ +K
Sbjct: 134 LTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEG----IAIFCML-LTYYMWIKAVK 188
Query: 195 KKSL-WGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYP 253
S+ W A L + +W G F LI + L + G+ F Y
Sbjct: 189 TGSICWAAKCALAYFYMVSSWGGYVF----LINLIPLHVLVLMLTGR------FSHRIYV 238
Query: 254 AYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKFLNYSDKK---HRF 310
AY + +G L+ I+ +G + E G + ++ F++Y K +F
Sbjct: 239 AYCTVYCLGTILSRQ-ISFVGFQPVLSSEHMAGFGVFGLCQIHA--FVDYLRSKLNPQQF 295
Query: 311 AVV--AVIVLLGFA----GAYAYVGPKLFRLMGGAYQ---------STQVYQTVQELAKT 355
V+ +VI L+GF GA + K+ G Y + + +V E T
Sbjct: 296 EVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPT 355
Query: 356 TLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYL 415
T S YY F L + F+ +GLY S S+ + +++ + S+Y
Sbjct: 356 TWSS---YY---------FDLQLLVFMFPVGLYYCF----SNLSDARIFIIMYGVTSMYF 399
Query: 416 LSLAVRFLFLASYAIALFSGIFAGFTMEVI----------EKMKEN------VGIKAALG 459
++ VR + + + +++ SGI + +K K+ + I+ A G
Sbjct: 400 SAVMVRLMLVLAPVMSILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKIEVASG 459
Query: 460 IAIAVMILMVPITH-----------GPVIARNAKALKVSEIETTGWEQVLKWLNENTSKY 508
+ + + ++ T P I +A+ S I + + WL NT +
Sbjct: 460 MILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPED 519
Query: 509 ATATSWWDYGYWI 521
A SWWDYGY I
Sbjct: 520 AKVMSWWDYGYQI 532
>gi|6680498 intergral membrane protein 1 [Mus musculus]
>gi|1174470|sp|P46978|STT3_MOUSE OLIGOSACCHARYL
TRANSFERASE STT3 SUBUNIT HOMOLOG (B5) (INTEGRAL MEMBRANE
PROTEIN 1) >gi|508543|gb|AAB47775.1| (L34260) integral
membrane protein 1 [Mus musculus]
>gi|1588285|prf||2208301A integral membrane protein [Mus
musculus]
Length = 705
Score = 81.5 bits (198), Expect = 4e-14
Identities = 125/560 (22%), Positives = 226/560 (40%), Gaps = 107/560 (19%)
Query: 25 LLKRILIPLA-VIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPKYY----P 79
LLK +++ +A V+ F + + + + DP ++++ + + +EG K++
Sbjct: 17 LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDP--YFNYRTTRFLAEEGFYKFHNWFDD 74
Query: 80 MAEAPFGSLIGEPL--GLYILPAIFYKVVSVFGYN---EFQAFLMWPPFVGFLGVIAVYL 134
A P G +IG + GL I A Y V+ F + P F F ++ Y
Sbjct: 75 RAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVT-YH 133
Query: 135 LGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIK 194
L +++ + AGL AA +++V SR+ +G+ +G + +F ++ + YY+ +K
Sbjct: 134 LTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEG----IAIFCML-LTYYMWIKAVK 188
Query: 195 KKSL-WGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYP 253
S+ W A L + +W G F LI + L + G+ F Y
Sbjct: 189 TGSIYWAAKCALAYFYMVSSWGGYVF----LINLIPLHVLVLMLTGR------FSHRIYV 238
Query: 254 AYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYG----GKFLNYSDKK-- 307
AY + +G L++ I+ +G F+ L + ++G F++Y K
Sbjct: 239 AYCTVYCLGTILSMQ-ISFVG------FQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLN 291
Query: 308 -HRFAVV--AVIVLLGFA----GAYAYVGPKLFRLMGGAYQ---------STQVYQTVQE 351
+F V+ +VI L+GF GA + K+ G Y + + +V E
Sbjct: 292 PQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSE 351
Query: 352 LAKTTLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIM 411
TT S YY F L + F+ +GLY S S+ + +++ +
Sbjct: 352 HQPTTWSS---YY---------FDLQLLVFMFPVGLYYCF----SNLSDARIFIIMYGVT 395
Query: 412 SLYLLSLAVRFLFLASYAIALFSGIFAGFTMEVIEKMKENVGI----------------- 454
S+Y ++ VR + + + + + SGI +V+ +N+ I
Sbjct: 396 SMYFSAVMVRLMLVLAPVMCILSGIGVS---QVLSTYMKNLDISRPDKKSKKQQDSTYPI 452
Query: 455 --KAALGIAIAVMILMVPITH-----------GPVIARNAKALKVSEIETTGWEQVLKWL 501
+ A G+ + + ++ T P I +A+ S I + + WL
Sbjct: 453 KNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWL 512
Query: 502 NENTSKYATATSWWDYGYWI 521
NT + A SWWDYGY I
Sbjct: 513 RHNTPEDAKVMSWWDYGYQI 532
>pir||S70029 probable transmembrane protein TMC - human
Length = 705
Score = 80.4 bits (195), Expect = 9e-14
Identities = 125/560 (22%), Positives = 226/560 (40%), Gaps = 107/560 (19%)
Query: 25 LLKRILIPLA-VIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPKYY----P 79
LLK +++ +A V+ F + + + + DP ++++ + + +EG K++
Sbjct: 17 LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDP--YFNYRTTRFLSEEGFYKFHNWFDD 74
Query: 80 MAEAPFGSLIGEPL--GLYILPAIFYKVVSVFGYN---EFQAFLMWPPFVGFLGVIAVYL 134
A P G +IG + GL I A Y V+ F + P F F ++ Y
Sbjct: 75 RAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVT-YH 133
Query: 135 LGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIK 194
L +++ + AGL AA +++V SR+ +G+ +G + +F ++ + YY+ +K
Sbjct: 134 LTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEG----IAIFCML-LTYYMWIKAVK 188
Query: 195 KKSL-WGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYP 253
S+ W A L + +W G F LI + L + G+ F Y
Sbjct: 189 TGSICWAAKCALAYFYMVSSWGGYVF----LINLIPLHVLVLMLTGR------FSHRIYV 238
Query: 254 AYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYG----GKFLNYSDKK-- 307
AY + +G L++ I+ +G F+ L + ++G F++Y K
Sbjct: 239 AYCTVYCLGTILSMQ-ISFVG------FQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLN 291
Query: 308 -HRFAVV--AVIVLLGFA----GAYAYVGPKLFRLMGGAYQ---------STQVYQTVQE 351
+F V+ +VI L+GF GA + K+ G Y + + +V E
Sbjct: 292 PQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSE 351
Query: 352 LAKTTLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIM 411
TT S YY F L + F+ +GLY S S+ + +++ +
Sbjct: 352 HQPTTWSS---YY---------FDLQLLVFMFPVGLYYCF----SNLSDARIFIIMYGVT 395
Query: 412 SLYLLSLAVRFLFLASYAIALFSGIFAGFTMEVIEKMKENVGI----------------- 454
S+Y ++ VR + + + + + SGI +V+ +N+ I
Sbjct: 396 SMYFSAVMVRLMLVLAPVMCILSGIGVS---QVLSTYMKNLDISRPDKKSKKQQDSTYPI 452
Query: 455 --KAALGIAIAVMILMVPITH-----------GPVIARNAKALKVSEIETTGWEQVLKWL 501
+ A G+ + + ++ T P I +A+ S I + + WL
Sbjct: 453 KNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARDGDGSRIIFDDFREAYYWL 512
Query: 502 NENTSKYATATSWWDYGYWI 521
NT + A SWWDYGY I
Sbjct: 513 RHNTPEDAKVMSWWDYGYQI 532
>gb|AAK41316.1| Oligosaccharyl transferase STT3 subunit (B5) (integral membrane
protein 1) [Sulfolobus solfataricus]
Length = 764
Score = 71.8 bits (173), Expect = 3e-11
Identities = 101/457 (22%), Positives = 185/457 (40%), Gaps = 52/457 (11%)
Query: 86 GSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMWPPFV-GFLGVIAVYLLGRKVLNE-W 143
G+ IG P + + FY +G N ++ + LGVIA YL + N
Sbjct: 85 GNTIGLPFLVALASLPFY---GTYGANAVYTVAIFSDILLAGLGVIASYLSIESITNSRL 141
Query: 144 AGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIKKKSLW---- 199
AG AA I++VS A + G LF++ +L +KKK++W
Sbjct: 142 AGYMAAAIIAVSPALTYKNLLGGLPKTSWGAVFILFAI-----FLLNQGLKKKNIWYGIP 196
Query: 200 GAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYPAYLAIL 259
+ + LA IS G + L+V A+F I L +I + ++L L
Sbjct: 197 AGIVLFLAEISWGGYTYIDLSLLV----AAFLLILLNRNDEITANLYTIMVVVTSFLTSL 252
Query: 260 AIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKFLNYSDKKHRFAVVAVIVLL 319
A + G+A + + ++L L L T+ K + S AV+ I+ L
Sbjct: 253 APNNIGFMSGLAHGFSLLLISAVLYLDLYLSRTLP----KEIVDSRNLIVIAVLIFILTL 308
Query: 320 GFAG------AYAYVGPKLFRLMGGAYQST-QVYQTVQELAKTTLSDIKLYYGVEGNNGL 372
G +G A + + + ++ YQ T + +TV E ++ + +G
Sbjct: 309 GLSGLSILRPTSAPIPSRYYAIINPFYQVTVPIDKTVAEYIPQPITAMIQDFG------- 361
Query: 373 VFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAVRFLFLASYAIAL 432
I FL ++G+Y L+++ ++L V + S++ S +Y +A
Sbjct: 362 -----IALFLSVIGMYY--LIRRGNLVGLWLL--VLGVASIFGTSEQPYLFNYTAYMVAT 412
Query: 433 FSGIFAGFTME-VIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARNAKALKVSEIET 491
G+ + + +++ +K G K +G +A++ + + G + + ++ T
Sbjct: 413 LGGLGVYYISDNLLKGVKNGNGNKILVGFILALVGISLVADAGLATLASNEPPAITNAAT 472
Query: 492 T------GWEQVLKWLNENTSKYATATSWWDYGYWIE 522
+ W W+ ++ + A SWWDYGYW+E
Sbjct: 473 SFLTTNYSWVSAANWIRTHSPQNAFVLSWWDYGYWLE 509
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.322 0.142 0.420
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 371336983
Number of Sequences: 2977
Number of extensions: 16760926
Number of successful extensions: 40163
Number of sequences better than 1.0e-10: 9
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 40142
Number of HSP's gapped (non-prelim): 11
length of query: 976
length of database: 189,106,746
effective HSP length: 56
effective length of query: 920
effective length of database: 155,591,474
effective search space: 143144156080
effective search space used: 143144156080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 170 (70.6 bits)