BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB2202 (PAB2202) DE:OLIGOSACCHARYL TRANSFERASE
         (976 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75212 oligosaccharyl transferase PAB2202 - Pyrococcus abys...  1966  0.0
pir||C71248 hypothetical protein PH0242 - Pyrococcus horikoshii ...  1559  0.0
pir||B75059 probable transmembrane oligosaccharyl transferase PA...   120  1e-25
pir||D71072 hypothetical protein PH1271 - Pyrococcus horikoshii ...   118  2e-25
pir||C75100 hypothetical protein PAB1586 - Pyrococcus abyssi (st...   105  3e-21
gi|4504787 integral membrane protein 1; integral transmembrane p...    87  1e-15
gi|6680498 intergral membrane protein 1 [Mus musculus] >gi|11744...    82  4e-14
pir||S70029 probable transmembrane protein TMC - human                 80  9e-14
gb|AAK41316.1| Oligosaccharyl transferase STT3 subunit (B5) (int...    72  3e-11

>pir||E75212 oligosaccharyl transferase PAB2202 - Pyrococcus abyssi  (strain
           Orsay) >gi|5457657|emb|CAB49148.1| (AJ248283)
           OLIGOSACCHARYL TRANSFERASE [Pyrococcus abyssi]
           Length = 976
           
 Score = 1966 bits (5037), Expect = 0.0
 Identities = 976/976 (100%), Positives = 976/976 (100%)

Query: 1   MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF 60
           MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF
Sbjct: 1   MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF 60

Query: 61  YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW 120
           YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW
Sbjct: 61  YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW 120

Query: 121 PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS 180
           PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS
Sbjct: 121 PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS 180

Query: 181 LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK 240
           LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK
Sbjct: 181 LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK 240

Query: 241 IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF 300
           IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF
Sbjct: 241 IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF 300

Query: 301 LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI 360
           LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI
Sbjct: 301 LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI 360

Query: 361 KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV 420
           KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV
Sbjct: 361 KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV 420

Query: 421 RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN 480
           RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN
Sbjct: 421 RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN 480

Query: 481 AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD 540
           AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD
Sbjct: 481 AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD 540

Query: 541 RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR 600
           RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR
Sbjct: 541 RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR 600

Query: 601 GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI 660
           GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI
Sbjct: 601 GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI 660

Query: 661 PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP 720
           PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP
Sbjct: 661 PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP 720

Query: 721 VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY 780
           VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY
Sbjct: 721 VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY 780

Query: 781 AIGNKTEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNGEI 840
           AIGNKTEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNGEI
Sbjct: 781 AIGNKTEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNGEI 840

Query: 841 ANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMDTF 900
           ANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMDTF
Sbjct: 841 ANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMDTF 900

Query: 901 FITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAEKE 960
           FITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAEKE
Sbjct: 901 FITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAEKE 960

Query: 961 YVMAEVRASAPHHGSE 976
           YVMAEVRASAPHHGSE
Sbjct: 961 YVMAEVRASAPHHGSE 976


>pir||C71248 hypothetical protein PH0242 - Pyrococcus horikoshii
           >gi|3256631|dbj|BAA29314.1| (AP000001) 976aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 976
           
 Score = 1559 bits (3991), Expect = 0.0
 Identities = 748/978 (76%), Positives = 851/978 (86%), Gaps = 4/978 (0%)

Query: 1   MVKTKVKEEKEEKSEKSEGKSLYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTF 60
           MVK+KVK+ ++ K E  E +S Y LLK++LIP+ V GF IYA+YLRHLTAGKYFPDPDTF
Sbjct: 1   MVKSKVKKVEKGK-EGEEKRSTYVLLKKVLIPILVFGFAIYAFYLRHLTAGKYFPDPDTF 59

Query: 61  YHFEIYKLVLKEGLPKYYPMAEAPFGSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMW 120
           YHFEIYKLVLKEGLP+YYPM++APFGSLIGEPLGLY+LPA FYKVVS+FGYNE QAFL+W
Sbjct: 60  YHFEIYKLVLKEGLPRYYPMSDAPFGSLIGEPLGLYLLPAAFYKVVSLFGYNELQAFLLW 119

Query: 121 PPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFS 180
           PPFVGFLGVIAVYLLGRKVLNEW GLW AV+L+VSTANFSRTFSGNARGDGPFM LF+F+
Sbjct: 120 PPFVGFLGVIAVYLLGRKVLNEWTGLWGAVVLTVSTANFSRTFSGNARGDGPFMALFIFA 179

Query: 181 LVAMLYYLKENDIKKKSLWGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGK 240
            VAMLYYLKE++  +K ++G +FVLL  ISLGAWNGSPFGLMVL+GFAS QTI LFIFGK
Sbjct: 180 SVAMLYYLKESNKTRKIIYGTLFVLLTVISLGAWNGSPFGLMVLLGFASLQTIILFIFGK 239

Query: 241 IKELKKFVKEFYPAYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKF 300
           ++ELKKFVKEFYPAYLAILA GY LT PGI KIGGFI+FAFEVFLGL+ L+ IMLYGG++
Sbjct: 240 LEELKKFVKEFYPAYLAILAFGYALTFPGIVKIGGFIRFAFEVFLGLIFLLVIMLYGGRY 299

Query: 301 LNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQVYQTVQELAKTTLSDI 360
           LNYSDKKHRF VV +IVLLGF GAYAYVGPKLFRLMGGAYQSTQVY+TVQELAKTT+ D+
Sbjct: 300 LNYSDKKHRFLVVTIIVLLGFGGAYAYVGPKLFRLMGGAYQSTQVYETVQELAKTTIGDV 359

Query: 361 KLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAV 420
           K YYGVE  NGL+FFLSIPG LI+L  YL  L KK++S NE + +LVFY MSLYLL LAV
Sbjct: 360 KAYYGVESGNGLIFFLSIPGLLILLTKYLYDLFKKAKSDNETLFALVFYTMSLYLLYLAV 419

Query: 421 RFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARN 480
           RFLFLASYA+ALF GIF GF+M+VIEKMKEN+GIKAALGI +++MIL++P  H PV+AR+
Sbjct: 420 RFLFLASYAVALFFGIFIGFSMDVIEKMKENIGIKAALGIVLSLMILVIPFVHAPVLARS 479

Query: 481 AKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARD 540
           A+ALK +EIE TGWEQ LKWL  NTSKYATATSWWDYGYWIESSLLG+RRASADGGHARD
Sbjct: 480 ARALKNTEIEVTGWEQALKWLRSNTSKYATATSWWDYGYWIESSLLGNRRASADGGHARD 539

Query: 541 RDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGR 600
           RDHILALFLARDGN+SEVDFESWELNYFIIYLNDWAKFNAISYLGGAITR+EYNGDE GR
Sbjct: 540 RDHILALFLARDGNISEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRKEYNGDENGR 599

Query: 601 GQVTTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLLIPGNKKI 660
           G+VTTIL  Q +G +YVNPYA I ++V+Q N T ++ VN+ G+ ECSPI ++  PGN KI
Sbjct: 600 GRVTTILLTQAAGNVYVNPYARIVIKVIQQNKTRRIAVNI-GQLECSPILSVAFPGNIKI 658

Query: 661 PGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIPISKYSGFTEKLYSNFVP 720
            G+GRCSDGSPFPYV+YL P+ G++ YYKVATSNF+KLAF IP S YS F EKL+SNF+P
Sbjct: 659 KGSGRCSDGSPFPYVVYLTPSLGVLAYYKVATSNFVKLAFGIPTSSYSEFAEKLFSNFIP 718

Query: 721 VYGYGNVIVYEFRPFAIYRIEELINGTWKAVNSLTPGKHELKLYISAFGRDIRNATLYVY 780
           VY YG+VIVYEFRPFAIY+IE+ INGTW+ V  L+PGKH L+LYISAFGRDI+NATLYVY
Sbjct: 719 VYQYGSVIVYEFRPFAIYKIEDFINGTWREVGKLSPGKHTLRLYISAFGRDIKNATLYVY 778

Query: 781 AI-GNK-TEKIKIGEIEYMNHLNEKPIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPKLNG 838
           A+ G K  ++IK+GEI+YMNHL E PIIVNVTLP A+KYR +L QKGPVGVLTGP ++NG
Sbjct: 779 ALNGTKIIKRIKVGEIKYMNHLEEYPIIVNVTLPTAQKYRFILAQKGPVGVLTGPVRVNG 838

Query: 839 EIANPIRIAREGEKGTLSLKVGVDKDYTADLYLRATFIYLVRKEGKSNDDYNAAFEPHMD 898
           +I NP  I REGE G L LKVGVDK+YTADLYLRATFIYLVRK GKSN+DY+A+FEPHMD
Sbjct: 839 KITNPAYIMREGESGRLELKVGVDKEYTADLYLRATFIYLVRKGGKSNEDYDASFEPHMD 898

Query: 899 TFFITKLKGGIKLHKGDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAE 958
           TFFITKLK GIKL  G+N +     MP   ISSYKEKLEKE+GDKLIIRGIRVEPVFI E
Sbjct: 899 TFFITKLKEGIKLRPGENEIVVNAEMPKNAISSYKEKLEKEHGDKLIIRGIRVEPVFIVE 958

Query: 959 KEYVMAEVRASAPHHGSE 976
           KEY M EV ASAPHH SE
Sbjct: 959 KEYTMIEVSASAPHHSSE 976


>pir||B75059 probable transmembrane oligosaccharyl transferase PAB0974 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458880|emb|CAB50367.1| (AJ248287) TRANSMEMBRANE
           OLIGOSACCHARYL TRANSFERASE, PUTATIVE. [Pyrococcus
           abyssi]
           Length = 766
           
 Score =  120 bits (297), Expect = 1e-25
 Identities = 151/623 (24%), Positives = 274/623 (43%), Gaps = 85/623 (13%)

Query: 28  RILIPLAV-IGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLP-KYYPMAEAPF 85
           +I +P+ V +G  +    LR     KY    D ++H    +  LK G    ++ +A  P+
Sbjct: 10  KIALPIVVLVGVTLRVIPLRF----KYLLGYDPYFHLAYIEESLKAGKWFNFFTIANGPW 65

Query: 86  GSLIGE--PLGLYILPAIFYKVVSVFGYNEFQAFLMWPPFVGFLGVIAVYLLGRKVLNEW 143
           G  I    PLGL++ PA  Y+ + VFG +    F + P   G L ++  Y+   K+  + 
Sbjct: 66  GFQIKSFHPLGLWMTPAYIYRFLKVFGISVQTVFKITPVIFGTLTIVFFYISLLKLYGKE 125

Query: 144 AGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIKKKSLWGAVF 203
              +A++ L++S  +  R+ +   RGD   +  +  +L  + Y L+    ++   +  V 
Sbjct: 126 KAFFASIFLALSFGHIFRSMANYYRGDNYMLFWYSLALAGIAYALRTKGYRRLVFY-LVP 184

Query: 204 VLLASISLGAWNGSPFGLMVLIGF-ASFQTIALFIFGKIKE-LKKFVKEFYPAYLAILA- 260
            L + IS   W  + + L V +     F  I  F+  K +  L  F+     A+ AI+A 
Sbjct: 185 TLASGISSVFWQ-AYYPLFVFLSLNGVFLAIGSFLLDKKRNFLDSFIIILSTAFGAIIAN 243

Query: 261 -----IGYGLTIPG----IAKIG----------GFIKFAFEVFLGLVLLVTIMLYGGKFL 301
                 GYG+        ++K+G           FI   + V + L LL+ I+L+  +F+
Sbjct: 244 YLGEKFGYGMLGYNRQHIVSKLGIKLGKIRDAYLFIHLHYLVPISLGLLI-ILLFLSRFV 302

Query: 302 NYSDKKHRFAVVAVIVLLGFAGAYAYV--GPKLFRLMG--GAYQSTQVYQTVQELAKTTL 357
                K + A V +++ LG       +   P L  L+G    ++ST + +T      T  
Sbjct: 303 -----KSKRAKVGIVIGLGTVSILIILLKFPALRGLLGIFDMFKSTPIMET----RPTNF 353

Query: 358 SDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLS 417
            D+   + +      +F L +         +L    +K ++ + ++L L+  + SLY+L 
Sbjct: 354 HDLWKAFSIS-----IFLLPL--------FFLRFHPEKVKTEDFFLLGLI--VPSLYMLL 398

Query: 418 LAVRFLFLASYAIALFSGI--FAGFTMEVIEKMKENVGIKAALGIAIAVMILMVPITHGP 475
              RF+F+ S A+A  +GI    G+++ VI++ K     + AL     ++++++ I +G 
Sbjct: 399 AWARFVFVGSLAVATMAGIGLVEGYSL-VIQRRKSGKASRVAL-----ILLILLLIVNGA 452

Query: 476 VIARNAKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSLLGHRRASADG 535
              +N   L +  +    WE  L WL  N+++     +WWDYG WI      + R +   
Sbjct: 453 FTLKN--CLSMRPLINKEWENALIWLKNNSNENDVILAWWDYGAWITY----YSRRAPVA 506

Query: 536 GHARDRDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNG 595
             A + D  L    AR+ +       S  ++Y I+   D+ KF++I       T    +G
Sbjct: 507 EIAPNPDVALYYLGARNRDW----IMSLGVDYVIVSYYDFLKFSSI-----VRTASAQSG 557

Query: 596 DETGRGQVTTILPLQGS-GGIYV 617
               +     +LPL  S GGI +
Sbjct: 558 YNLIKRYWIAVLPLTSSYGGILI 580


>pir||D71072 hypothetical protein PH1271 - Pyrococcus horikoshii
           >gi|3257691|dbj|BAA30374.1| (AP000005) 758aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 758
           
 Score =  118 bits (294), Expect = 2e-25
 Identities = 148/601 (24%), Positives = 250/601 (40%), Gaps = 83/601 (13%)

Query: 52  KYFPDPDTFYHFEIYKLVLKEGL-PKYYPMAEAPFGSLIG--EPLGLYILPAIFYKVVSV 108
           KY    D ++H    + V K G    +   A  P+G  +    PLGL++ P   YK++ V
Sbjct: 25  KYLLGYDPYFHLAYIEEVNKVGKWINFLTFAGGPWGYQVKLFHPLGLWMTPLYLYKLLKV 84

Query: 109 FGYNEFQAFLMWPPFVGFLGVIAVYLLGRKVLNEWAGLWAAVILSVSTANFSRTFSGNAR 168
           FG +    F + P   G L VI +YL   K+ +E    +    L++S  +  R+ +   R
Sbjct: 85  FGVSLTTTFKITPVIFGVLTVIFLYLSLLKLYDEKRAFFGGFFLAISYGHVFRSMANYYR 144

Query: 169 GDGPFMTLFLFSL--VAMLYYLKENDIK-KKSLWGAVFVLLASISLGAWNGSPFGLMVLI 225
           GD   +  +  +L  +++   +K+   K K+ ++  + VL +  S   W         L+
Sbjct: 145 GDNYMLFWYSVALLGISLALGIKKGKWKYKRLIFYTLPVLASGFSAIFWQAYYPIFAFLL 204

Query: 226 GFASFQTIALFIFGKIKELKKFVKEFYPAYLAILAIGYGLTIPG-IAKIGGFIKFAFEVF 284
             A    +  FI  K K L         + + IL+  +G+ +   +  I G+    +  +
Sbjct: 205 SNALLLAVGAFILKKDKYL-------LDSIILILSTAFGVLLANYLGGIFGYGMLGYAKW 257

Query: 285 LGLVLLVTIMLYGGKFLNYSDKKH-------RFAVVAVIVLLG-----------FAGAYA 326
           LG  +   + L  G   +     H         + V V++LLG           F G  +
Sbjct: 258 LGKSVAKKLGLEFGYLKDVYLILHLKYLVPISLSFVLVLILLGFLTKDIRIRSLFLGIAS 317

Query: 327 YVGP----KLFRLMGGAYQSTQVYQ--TVQELAKTTLSDIKLYYGVEGNNGLVFFLSIPG 380
           ++G     K F  +        +++   + E   T+  D+   +       L FFL+ P 
Sbjct: 318 FIGIIILFKRFEALKELSTGFGIFKEAPILETQPTSFKDLWAAF------SLSFFLT-PL 370

Query: 381 FLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAVRFLFLASYAIALFSGIFAGF 440
           F I          +  +   E  L+L   I S+Y+L    RFLF+ S AIA+ SGI    
Sbjct: 371 FFI----------RFKKPRVEDFLTLGLIIPSVYMLKTWTRFLFIGSMAIAIMSGI---G 417

Query: 441 TMEVIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARNAKALKVSEIETTGWEQVLKW 500
            +E+ E +K  +  K AL   I  ++++  +  G       +   +       WE+ LKW
Sbjct: 418 IVELYEAIKPRLNGKKALATGIITLVILPGVIAG---LSFKEVCSLHPEMNEAWERALKW 474

Query: 501 LNENTSKYATATSWWDYGYWIESSLLGHRRASADGGHARDRDHILALFLARDGNVSEVDF 560
           L  N+++     +WWD+G++I  +    R   A GG +      +AL+L    N      
Sbjct: 475 LKNNSNENDVILAWWDWGHFI--TYYARRSPIAQGGPSVG----VALYLLGKLN------ 522

Query: 561 ESWELN----YFIIYLNDWAKFNAISYLGGAITRREYNGDETGRGQVTTILPLQGSGGIY 616
           E+W +N    Y I+   D+ KF AI  L  A   + YN     RG    +LPL+ S G  
Sbjct: 523 ENWAINLGVDYVIVSYYDFLKFGAI--LSTANLSKRYN----IRGYGLVVLPLRASTGAL 576

Query: 617 V 617
           +
Sbjct: 577 I 577


>pir||C75100 hypothetical protein PAB1586 - Pyrococcus abyssi (strain Orsay)
           >gi|5458616|emb|CAB50104.1| (AJ248286) hypothetical
           protein [Pyrococcus abyssi]
           Length = 765
           
 Score =  105 bits (259), Expect = 3e-21
 Identities = 149/633 (23%), Positives = 257/633 (40%), Gaps = 96/633 (15%)

Query: 22  LYPLLKRILIPLAVIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEG-LPKYYPM 80
           L P   R+ +P+ ++   +  +Y       KY    D + H    +  LK G    ++ +
Sbjct: 6   LNPFKPRVALPIIIV---VSLFYRLLTFRFKYLLGYDPYLHLAYIEEALKAGEWFNFFTL 62

Query: 81  AEAPFGSLIGE--PLGLYILPAIFYKVVSVFGYNEFQAFLMWPPFVGFLGVIAVYLLGRK 138
           A+AP+G  + +  PLGL+++PA  +K+ ++  Y    AF + P   G L V+  YL   K
Sbjct: 63  AKAPWGMQMRKFHPLGLWMIPAYIHKIFNIPLYT---AFKITPVIFGVLTVVFTYLALLK 119

Query: 139 VLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIKKKSL 198
           +  E    +A++ L VS  +  R+ +   RGD   +  +  + + +   L E    K+  
Sbjct: 120 LYGERKAFYASLFLGVSYGHVFRSMANYYRGDNYMLFWYSLAFLGIALALGE----KRRS 175

Query: 199 WG---AVFVLLASISLGA----WNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEF 251
           W     +F L+  I  G     W       + L+G A   +   F+   ++E K  +   
Sbjct: 176 WRYRRLIFYLIPGIGSGLASIFWQAYYPIFIFLLGNALLLSFGAFL---LREDKYILDGL 232

Query: 252 YPAYLAILA----------IGYGLT--IPGIAKI-------------GGFIKFAFEVFLG 286
             A L +L            GYG+     G+ K                F+    +  + 
Sbjct: 233 LLASLTVLGAFMANYLGGKFGYGMFGYDHGLGKTVAEKLSLELSTIKDAFLLVYLKYLVP 292

Query: 287 LVLL-VTIMLYGGKFLNYSDKKHRFAVVAVIVLLGFAGAYAYVGPKLFRLMGGAYQSTQV 345
           LV+L + I+L    FL     K R  +   I+LLG        G  L  L  G     +V
Sbjct: 293 LVVLGIVILLVVSYFLK--SLKARAVLSTFIILLGLLIVLLKFGSLLKDLSTGFGMFKEV 350

Query: 346 YQTVQELAKTTLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLS 405
              + E      SD+   + +      +FFL                 ++ +  +   L 
Sbjct: 351 --PIAETVPPKFSDLWAAFALSLFLSPLFFLEF---------------RRPKVQDFMFLG 393

Query: 406 LVFYIMSLYLLSLAVRFLFLASYAIALFSGIFAGFTMEVIEKMKENVGIKAALGIAIAVM 465
           L+  I SLY+     RFLF+ S A+ L +GI      E I        ++  L +A+ ++
Sbjct: 394 LI--IPSLYMFLTWTRFLFIGSLAVTLMAGIGLISAYERI--------LRKGLALALILL 443

Query: 466 ILMVPITHGPVIARNAKALKVSEIETTGWEQVLKWLNENTSKYATATSWWDYGYWIESSL 525
           +++  +  G  +  N  A K   +    W   L+WL  N+++     +WWDYG WI  + 
Sbjct: 444 VILPGVNAG--VGFNYVA-KQKPLINDYWVNALRWLRSNSNENDIVLAWWDYGQWI--TY 498

Query: 526 LGHRRASADGGHARDRDHILALFLARDGNVSEVDFESWELNYFIIYLNDWAKFNAISYLG 585
              R   A G  +      +AL+L   G ++    ES  ++Y I+   D+ KF AI  + 
Sbjct: 499 YARRAPIAQGSPSIG----VALYLL--GKLNYRWAESLGVDYVIVSYYDFLKFPAI--VA 550

Query: 586 GAITRREYNGDETGRGQVTTILPL-QGSGGIYV 617
            A    +YN      G    ++PL + +G ++V
Sbjct: 551 TANMHPKYN----LTGYALVVVPLVERAGDVFV 579


>gi|4504787 integral membrane protein 1; integral transmembrane protein 1;
           Transmembrane conserved gene [Homo sapiens]
           >gi|1174469|sp|P46977|STT3_HUMAN OLIGOSACCHARYL
           TRANSFERASE STT3 SUBUNIT HOMOLOG (B5) (INTEGRAL MEMBRANE
           PROTEIN 1) (TMC) >gi|624704|gb|AAB05994.1| (L38961)
           putative transmembrane protein precursor [Homo sapiens]
           >gi|1588286|prf||2208301B integral membrane protein
           [Homo sapiens]
           Length = 705
           
 Score = 86.6 bits (211), Expect = 1e-15
 Identities = 125/553 (22%), Positives = 226/553 (40%), Gaps = 93/553 (16%)

Query: 25  LLKRILIPLA-VIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPKYY----P 79
           LLK +++ +A V+ F    + +    +  +  DP  ++++   + + +EG  K++     
Sbjct: 17  LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDP--YFNYRTTRFLAEEGFYKFHNWFDD 74

Query: 80  MAEAPFGSLIGEPL--GLYILPAIFYKVVSVFGYN---EFQAFLMWPPFVGFLGVIAVYL 134
            A  P G +IG  +  GL I  A  Y V+  F            + P F  F  ++  YL
Sbjct: 75  RAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTSIVT-YL 133

Query: 135 LGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIK 194
           L +++ +  AGL AA +++V     SR+ +G+   +G    + +F ++ + YY+    +K
Sbjct: 134 LTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEG----IAIFCML-LTYYMWIKAVK 188

Query: 195 KKSL-WGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYP 253
             S+ W A   L     + +W G  F    LI       + L + G+      F    Y 
Sbjct: 189 TGSICWAAKCALAYFYMVSSWGGYVF----LINLIPLHVLVLMLTGR------FSHRIYV 238

Query: 254 AYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKFLNYSDKK---HRF 310
           AY  +  +G  L+   I+ +G     + E   G  +     ++   F++Y   K    +F
Sbjct: 239 AYCTVYCLGTILSRQ-ISFVGFQPVLSSEHMAGFGVFGLCQIHA--FVDYLRSKLNPQQF 295

Query: 311 AVV--AVIVLLGFA----GAYAYVGPKLFRLMGGAYQ---------STQVYQTVQELAKT 355
            V+  +VI L+GF     GA   +  K+    G  Y          +  +  +V E   T
Sbjct: 296 EVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPT 355

Query: 356 TLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYL 415
           T S    YY         F L +  F+  +GLY       S  S+  +  +++ + S+Y 
Sbjct: 356 TWSS---YY---------FDLQLLVFMFPVGLYYCF----SNLSDARIFIIMYGVTSMYF 399

Query: 416 LSLAVRFLFLASYAIALFSGIFAGFTMEVI----------EKMKEN------VGIKAALG 459
            ++ VR + + +  +++ SGI     +             +K K+       + I+ A G
Sbjct: 400 SAVMVRLMLVLAPVMSILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKIEVASG 459

Query: 460 IAIAVMILMVPITH-----------GPVIARNAKALKVSEIETTGWEQVLKWLNENTSKY 508
           + + +   ++  T             P I  +A+    S I    + +   WL  NT + 
Sbjct: 460 MILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPED 519

Query: 509 ATATSWWDYGYWI 521
           A   SWWDYGY I
Sbjct: 520 AKVMSWWDYGYQI 532


>gi|6680498 intergral membrane protein 1 [Mus musculus]
           >gi|1174470|sp|P46978|STT3_MOUSE OLIGOSACCHARYL
           TRANSFERASE STT3 SUBUNIT HOMOLOG (B5) (INTEGRAL MEMBRANE
           PROTEIN 1) >gi|508543|gb|AAB47775.1| (L34260) integral
           membrane protein 1 [Mus musculus]
           >gi|1588285|prf||2208301A integral membrane protein [Mus
           musculus]
           Length = 705
           
 Score = 81.5 bits (198), Expect = 4e-14
 Identities = 125/560 (22%), Positives = 226/560 (40%), Gaps = 107/560 (19%)

Query: 25  LLKRILIPLA-VIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPKYY----P 79
           LLK +++ +A V+ F    + +    +  +  DP  ++++   + + +EG  K++     
Sbjct: 17  LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDP--YFNYRTTRFLAEEGFYKFHNWFDD 74

Query: 80  MAEAPFGSLIGEPL--GLYILPAIFYKVVSVFGYN---EFQAFLMWPPFVGFLGVIAVYL 134
            A  P G +IG  +  GL I  A  Y V+  F            + P F  F  ++  Y 
Sbjct: 75  RAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVT-YH 133

Query: 135 LGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIK 194
           L +++ +  AGL AA +++V     SR+ +G+   +G    + +F ++ + YY+    +K
Sbjct: 134 LTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEG----IAIFCML-LTYYMWIKAVK 188

Query: 195 KKSL-WGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYP 253
             S+ W A   L     + +W G  F    LI       + L + G+      F    Y 
Sbjct: 189 TGSIYWAAKCALAYFYMVSSWGGYVF----LINLIPLHVLVLMLTGR------FSHRIYV 238

Query: 254 AYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYG----GKFLNYSDKK-- 307
           AY  +  +G  L++  I+ +G      F+  L    +    ++G      F++Y   K  
Sbjct: 239 AYCTVYCLGTILSMQ-ISFVG------FQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLN 291

Query: 308 -HRFAVV--AVIVLLGFA----GAYAYVGPKLFRLMGGAYQ---------STQVYQTVQE 351
             +F V+  +VI L+GF     GA   +  K+    G  Y          +  +  +V E
Sbjct: 292 PQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSE 351

Query: 352 LAKTTLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIM 411
              TT S    YY         F L +  F+  +GLY       S  S+  +  +++ + 
Sbjct: 352 HQPTTWSS---YY---------FDLQLLVFMFPVGLYYCF----SNLSDARIFIIMYGVT 395

Query: 412 SLYLLSLAVRFLFLASYAIALFSGIFAGFTMEVIEKMKENVGI----------------- 454
           S+Y  ++ VR + + +  + + SGI      +V+    +N+ I                 
Sbjct: 396 SMYFSAVMVRLMLVLAPVMCILSGIGVS---QVLSTYMKNLDISRPDKKSKKQQDSTYPI 452

Query: 455 --KAALGIAIAVMILMVPITH-----------GPVIARNAKALKVSEIETTGWEQVLKWL 501
             + A G+ + +   ++  T             P I  +A+    S I    + +   WL
Sbjct: 453 KNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWL 512

Query: 502 NENTSKYATATSWWDYGYWI 521
             NT + A   SWWDYGY I
Sbjct: 513 RHNTPEDAKVMSWWDYGYQI 532


>pir||S70029 probable transmembrane protein TMC - human
           Length = 705
           
 Score = 80.4 bits (195), Expect = 9e-14
 Identities = 125/560 (22%), Positives = 226/560 (40%), Gaps = 107/560 (19%)

Query: 25  LLKRILIPLA-VIGFGIYAYYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPKYY----P 79
           LLK +++ +A V+ F    + +    +  +  DP  ++++   + + +EG  K++     
Sbjct: 17  LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDP--YFNYRTTRFLSEEGFYKFHNWFDD 74

Query: 80  MAEAPFGSLIGEPL--GLYILPAIFYKVVSVFGYN---EFQAFLMWPPFVGFLGVIAVYL 134
            A  P G +IG  +  GL I  A  Y V+  F            + P F  F  ++  Y 
Sbjct: 75  RAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVT-YH 133

Query: 135 LGRKVLNEWAGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIK 194
           L +++ +  AGL AA +++V     SR+ +G+   +G    + +F ++ + YY+    +K
Sbjct: 134 LTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEG----IAIFCML-LTYYMWIKAVK 188

Query: 195 KKSL-WGAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYP 253
             S+ W A   L     + +W G  F    LI       + L + G+      F    Y 
Sbjct: 189 TGSICWAAKCALAYFYMVSSWGGYVF----LINLIPLHVLVLMLTGR------FSHRIYV 238

Query: 254 AYLAILAIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYG----GKFLNYSDKK-- 307
           AY  +  +G  L++  I+ +G      F+  L    +    ++G      F++Y   K  
Sbjct: 239 AYCTVYCLGTILSMQ-ISFVG------FQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLN 291

Query: 308 -HRFAVV--AVIVLLGFA----GAYAYVGPKLFRLMGGAYQ---------STQVYQTVQE 351
             +F V+  +VI L+GF     GA   +  K+    G  Y          +  +  +V E
Sbjct: 292 PQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSE 351

Query: 352 LAKTTLSDIKLYYGVEGNNGLVFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIM 411
              TT S    YY         F L +  F+  +GLY       S  S+  +  +++ + 
Sbjct: 352 HQPTTWSS---YY---------FDLQLLVFMFPVGLYYCF----SNLSDARIFIIMYGVT 395

Query: 412 SLYLLSLAVRFLFLASYAIALFSGIFAGFTMEVIEKMKENVGI----------------- 454
           S+Y  ++ VR + + +  + + SGI      +V+    +N+ I                 
Sbjct: 396 SMYFSAVMVRLMLVLAPVMCILSGIGVS---QVLSTYMKNLDISRPDKKSKKQQDSTYPI 452

Query: 455 --KAALGIAIAVMILMVPITH-----------GPVIARNAKALKVSEIETTGWEQVLKWL 501
             + A G+ + +   ++  T             P I  +A+    S I    + +   WL
Sbjct: 453 KNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARDGDGSRIIFDDFREAYYWL 512

Query: 502 NENTSKYATATSWWDYGYWI 521
             NT + A   SWWDYGY I
Sbjct: 513 RHNTPEDAKVMSWWDYGYQI 532


>gb|AAK41316.1| Oligosaccharyl transferase STT3 subunit (B5) (integral membrane
           protein 1) [Sulfolobus solfataricus]
           Length = 764
           
 Score = 71.8 bits (173), Expect = 3e-11
 Identities = 101/457 (22%), Positives = 185/457 (40%), Gaps = 52/457 (11%)

Query: 86  GSLIGEPLGLYILPAIFYKVVSVFGYNEFQAFLMWPPFV-GFLGVIAVYLLGRKVLNE-W 143
           G+ IG P  + +    FY     +G N      ++   +   LGVIA YL    + N   
Sbjct: 85  GNTIGLPFLVALASLPFY---GTYGANAVYTVAIFSDILLAGLGVIASYLSIESITNSRL 141

Query: 144 AGLWAAVILSVSTANFSRTFSGNARGDGPFMTLFLFSLVAMLYYLKENDIKKKSLW---- 199
           AG  AA I++VS A   +   G            LF++     +L    +KKK++W    
Sbjct: 142 AGYMAAAIIAVSPALTYKNLLGGLPKTSWGAVFILFAI-----FLLNQGLKKKNIWYGIP 196

Query: 200 GAVFVLLASISLGAWNGSPFGLMVLIGFASFQTIALFIFGKIKELKKFVKEFYPAYLAIL 259
             + + LA IS G +      L+V    A+F  I L    +I      +     ++L  L
Sbjct: 197 AGIVLFLAEISWGGYTYIDLSLLV----AAFLLILLNRNDEITANLYTIMVVVTSFLTSL 252

Query: 260 AIGYGLTIPGIAKIGGFIKFAFEVFLGLVLLVTIMLYGGKFLNYSDKKHRFAVVAVIVLL 319
           A      + G+A     +  +  ++L L L  T+     K +  S      AV+  I+ L
Sbjct: 253 APNNIGFMSGLAHGFSLLLISAVLYLDLYLSRTLP----KEIVDSRNLIVIAVLIFILTL 308

Query: 320 GFAG------AYAYVGPKLFRLMGGAYQST-QVYQTVQELAKTTLSDIKLYYGVEGNNGL 372
           G +G        A +  + + ++   YQ T  + +TV E     ++ +   +G       
Sbjct: 309 GLSGLSILRPTSAPIPSRYYAIINPFYQVTVPIDKTVAEYIPQPITAMIQDFG------- 361

Query: 373 VFFLSIPGFLIILGLYLNALLKKSESSNEYMLSLVFYIMSLYLLSLAVRFLFLASYAIAL 432
                I  FL ++G+Y   L+++      ++L  V  + S++  S         +Y +A 
Sbjct: 362 -----IALFLSVIGMYY--LIRRGNLVGLWLL--VLGVASIFGTSEQPYLFNYTAYMVAT 412

Query: 433 FSGIFAGFTME-VIEKMKENVGIKAALGIAIAVMILMVPITHGPVIARNAKALKVSEIET 491
             G+   +  + +++ +K   G K  +G  +A++ + +    G     + +   ++   T
Sbjct: 413 LGGLGVYYISDNLLKGVKNGNGNKILVGFILALVGISLVADAGLATLASNEPPAITNAAT 472

Query: 492 T------GWEQVLKWLNENTSKYATATSWWDYGYWIE 522
           +       W     W+  ++ + A   SWWDYGYW+E
Sbjct: 473 SFLTTNYSWVSAANWIRTHSPQNAFVLSWWDYGYWLE 509


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.322    0.142    0.420 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 371336983
Number of Sequences: 2977
Number of extensions: 16760926
Number of successful extensions: 40163
Number of sequences better than 1.0e-10: 9
Number of HSP's better than  0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 40142
Number of HSP's gapped (non-prelim): 11
length of query: 976
length of database: 189,106,746
effective HSP length: 56
effective length of query: 920
effective length of database: 155,591,474
effective search space: 143144156080
effective search space used: 143144156080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 170 (70.6 bits)