BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2203 (asnS) DE:ASPARAGINYL-TRNA SYNTHETASE (EC 6.1.1.22)
(ASPARAGINE--TRNA LIGASE) (ASNRS)
(434 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75212 asparagine--tRNA ligase (EC 6.1.1.22) PAB2203 - Pyro... 891 0.0
pir||B71248 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus h... 846 0.0
emb|CAC11659.1| (AL445064) probable asparaginyl--tRNA synthetase... 432 e-120
sp|P39772|SYN_BACSU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 397 e-109
dbj|BAB05415.1| (AP001512) asparaginyl-tRNA synthetase [Bacillus... 396 e-109
pir||S71074 asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactob... 370 e-101
pir||S71072 asparagine--tRNA ligase (EC 6.1.1.22) asnS1 - Lactob... 369 e-101
sp|P54262|SYN_LACDE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 369 e-101
sp|P54263|SYN_THETH ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 353 2e-96
sp|O58776|SYD_PYRHO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 311 1e-83
pir||A75071 aspartyl-tRNA synthetase (asps) PAB0646 - Pyrococcus... 305 8e-82
sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 302 4e-81
gi|11498525 aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgi... 298 6e-80
sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 292 5e-78
pdb|1B8A|A Chain A, Aspartyl-Trna Synthetase >gi|4388837|pdb|1B8... 291 8e-78
sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 287 1e-76
gi|6321807 Asparaginyl-tRNA synthetase; Ded81p [Saccharomyces ce... 276 4e-73
gb|AAK40519.1| Aspartyl-tRNA synthetase (aspS) [Sulfolobus solfa... 273 3e-72
gb|AAD55420.1|AF181634_1 (AF181634) BcDNA.GH06451 [Drosophila me... 272 6e-72
pir||T39675 asparaginyl-trna synthetase - fission yeast (Schizo... 268 1e-70
sp|Q19722|SYN_CAEEL PROBABLE ASPARAGINYL-TRNA SYNTHETASE, CYTOPL... 266 3e-70
gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens] >gi|391505... 265 6e-70
gi|11426051 asparaginyl-tRNA synthetase [Homo sapiens] 265 6e-70
sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 260 2e-68
emb|CAC12075.1| (AL445066) aspartyl-tRNA synthetase related prot... 258 8e-68
sp|Q9Y9U7|SYD_AERPE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 257 2e-67
pir||C72527 probable aspartyl-tRNA synthetase APE2192 - Aeropyru... 249 5e-65
sp|P43829|SYN_HAEIN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 244 2e-63
pir||F82540 asparaginyl-tRNA synthetase XF2563 [imported] - Xyle... 243 2e-63
pir||A28209 60K filarial antigen - nematode (Brugia malayi) >gi|... 242 6e-63
sp|P10723|SYN_BRUMA ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (AS... 242 8e-63
pir||E82217 asparaginyl-tRNA synthetase VC1297 [imported] - Vibr... 240 3e-62
sp|P17242|SYN_ECOLI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 236 3e-61
pir||A82901 asparaginyl-tRNA synthetase UU365 [imported] - Ureap... 236 4e-61
sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 235 6e-61
sp|O51128|SYN_BORBU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 235 8e-61
emb|CAA10904.1| (AJ222644) asparaginyl-tRNA synthetase [Arabidop... 233 2e-60
sp|P52276|SYN_SYNY3 PROBABLE ASPARAGINYL-TRNA SYNTHETASE (ASPARA... 233 4e-60
sp|P47359|SYN_MYCGE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 232 7e-60
sp|P75521|SYN_MYCPN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 226 4e-58
gb|AAF61689.1| (AF219996) aspartyl-tRNA synthetase 2 [Thermus th... 222 5e-57
pir||H75443 aspartyl-tRNA synthetase, non-discriminating - Deino... 217 2e-55
sp|O83618|SYN_TREPA ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 215 1e-54
emb|CAB91185.1| (AL355921) asparaginyl-trna synthetase, mitochon... 208 8e-53
gb|AAD46681.1|AF170909_1 (AF170909) SYNC1 protein [Arabidopsis t... 206 3e-52
pir||H71612 asparagine--tRNA ligase (EC 6.1.1.22) (OO, TP) PFB05... 205 9e-52
sp|P57441|SYN_BUCAI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 205 9e-52
gb|AAD55509.1|AC008148_19 (AC008148) Similar to asparaginyl-tRN... 203 4e-51
gi|4557513 aspartyl-tRNA synthetase [Homo sapiens] >gi|135098|sp... 196 6e-49
gi|11429379 aspartyl-tRNA synthetase [Homo sapiens] 194 2e-48
pir||T40867 aspartate--tRNA ligase (EC 6.1.1.12) [similarity] - ... 192 6e-48
pir||T04810 aspartate--tRNA ligase homolog F10M23.210 - Arabidop... 191 1e-47
sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGA... 190 2e-47
gi|6319872 Asn-tRNA synthetase; Ycr024cp [Saccharomyces cerevisi... 187 2e-46
gb|AAF58445.1| (AE003820) Aats-asp gene product [Drosophila mela... 187 3e-46
gb|AAF57921.1| (AE003804) CG6796 gene product [Drosophila melano... 186 5e-46
gb|AAD21582.1| (AF113612) aspartyl tRNA synthetase [Drosophila m... 184 1e-45
gi|6323011 Aspartyl-tRNA synthetase, cytosolic; Dps1p [Saccharom... 181 1e-44
pdb|1ASZ|A Chain A, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.... 181 1e-44
pdb|1EOV|A Chain A, Free Aspartyl-Trna Synthetase (Asprs) (E.C. ... 181 1e-44
pir||T10672 aspartate--tRNA ligase homolog F6E21.100 - Arabidops... 180 4e-44
sp|Q03577|SYD_CAEEL PROBABLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE... 179 5e-44
dbj|BAA35676.1| (D90730) Asparaginyl-tRNA synthetase (EC 6.1.1.... 172 6e-42
dbj|BAB15655.1| (AK027094) unnamed protein product [Homo sapiens] 157 2e-37
pir||S70779 asparagine--tRNA ligase (EC 6.1.1.22) - Xenorhabdus ... 150 2e-35
emb|CAC11748.1| (AL445064) asparagine--tRNA ligase related prote... 145 1e-33
emb|CAA10905.1| (AJ222645) asparaginyl-tRNA synthetase [Arabidop... 144 2e-33
gb|AAD46682.1|AF170910_1 (AF170910) SYNC2 protein [Arabidopsis t... 144 2e-33
gb|AAF02166.1|AC009853_26 (AC009853) putative asparaginyl-tRNA s... 144 2e-33
pir||S77842 probable asparagine--tRNA ligase (EC 6.1.1.22) - Myc... 137 2e-31
sp|Q56112|SYN_SALTI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 119 5e-26
dbj|BAB04971.1| (AP001511) aspartyl-tRNA synthetase [Bacillus ha... 114 2e-24
sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 112 7e-24
sp|O67258|SYK_AQUAE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 111 1e-23
pir||G71451 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus h... 110 4e-23
sp|Q9RHV9|SYK_BACST LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 109 6e-23
pir||JC7205 lysine-tRNA ligase (AMP forming) (EC 6.1.1.6) - Baci... 109 6e-23
pir||C75215 asparaginyl-tRNA synthetase related protein PAB2356 ... 105 1e-21
pir||D82910 aspartyl-tRNA synthetase UU286 [imported] - Ureaplas... 104 2e-21
sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 104 2e-21
sp|Q9KGG4|SYK_BACHD LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 103 5e-21
emb|CAC08476.1| (AL392189) aspartyl-tRNA synthetase [Streptomyce... 102 8e-21
sp|Q9PEB6|SYK_XYLFA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 101 2e-20
sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 100 3e-20
sp|Q9PR83|SYK_UREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 100 5e-20
sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 99 7e-20
sp|Q9X231|SYK_THEMA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 99 7e-20
sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 98 2e-19
pir||H82627 aspartyl-tRNA synthetase XF1856 [imported] - Xylella... 97 3e-19
pir||I40523 asparagine--tRNA ligase (EC 6.1.1.22) - Bacillus sub... 96 6e-19
pir||F82234 aspartyl-tRNA synthetase VC1166 [imported] - Vibrio ... 94 2e-18
sp|O87821|SYK_RHIME LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 94 3e-18
pir||D75406 aspartyl-tRNA synthetase, discriminating - Deinococc... 93 5e-18
sp|Q9X1F4|SYD_THEMA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 92 1e-17
sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 92 2e-17
sp|O83950|SYD_TREPA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 91 2e-17
pir||E83524 aspartyl-tRNA synthetase PA0963 [imported] - Pseudom... 91 2e-17
sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 91 3e-17
sp|P57401|SYD_BUCAI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 90 4e-17
pir||B71442 probable asparagine--tRNA ligase - Arabidopsis thali... 90 6e-17
sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 89 8e-17
sp|P57512|SYK_BUCAI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 89 1e-16
sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSI... 89 1e-16
pdb|1E1O|A Chain A, Lysyl-Trna Synthetase (Lysu) Hexagonal For, ... 89 1e-16
sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 88 2e-16
pir||D83183 lysyl-tRNA synthetase PA3700 [imported] - Pseudomona... 88 2e-16
sp|O84546|SYD_CHLTR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 88 2e-16
pir||G81412 aspartate--tRNA ligase (EC 6.1.1.12) Cj0640c [import... 87 4e-16
sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 87 5e-16
sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE)... 86 7e-16
pdb|1BBU|A Chain A, Lysyl-Trna Synthetase (Lyss) Complexed With ... 86 7e-16
sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 86 7e-16
pir||E81660 aspartyl-tRNA synthetase TC0829 [imported] - Chlamyd... 86 9e-16
sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 85 1e-15
emb|CAB89697.1| (AJ276418) putative lysyl tRNA synthetase [Xanth... 85 1e-15
sp|Q9ZE17|SYD_RICPR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 85 1e-15
sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 85 2e-15
sp|Q9ZMP8|SYK_HELPJ LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 85 2e-15
sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 84 3e-15
pdb|1C0A|A Chain A, Crystal Structure Of The E. Coli Aspartyl-Tr... 84 3e-15
pir||S69892 lysine--tRNA ligase (EC 6.1.1.6) - Mycoplasma hominis 83 8e-15
sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 83 8e-15
sp|Q9ZLL9|SYD_HELPJ ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 82 1e-14
sp|P41908|SYNC_SACDO PUTATIVE ASPARAGINYL-TRNA SYNTHETASE, CYTOP... 82 1e-14
gb|AAA24096.1| (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1... 82 2e-14
pir||G81195 aspartyl-tRNA synthetase NMB0466 [imported] - Neisse... 80 4e-14
sp|Q9Z7P2|SYD_CHLPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 80 5e-14
pir||F81831 aspartate--tRNA ligase (EC 6.1.1.12) NMA2019 [import... 80 5e-14
sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 79 1e-13
sp|P75500|SYK_MYCPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 78 2e-13
sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 78 3e-13
pir||B81858 lysine--tRNA ligase (EC 6.1.1.6) NMA1638 [imported] ... 77 4e-13
pir||C81086 lysyl-tRNA synthetase, heat inducible NMB1425 [impor... 76 7e-13
sp|Q9KU60|SYK_VIBCH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 75 2e-12
sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 75 2e-12
dbj|BAA90843.1| (AB031211) LysS [Bacillus halodurans] 75 2e-12
sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 74 4e-12
pir||S77851 probable aspartate--tRNA ligase (EC 6.1.1.12) - Myco... 73 5e-12
pir||T04993 probable aspartate--tRNA ligase (EC 6.1.1.12) T16L1.... 70 6e-11
>pir||D75212 asparagine--tRNA ligase (EC 6.1.1.22) PAB2203 - Pyrococcus abyssi
(strain Orsay) >gi|5457656|emb|CAB49147.1| (AJ248283)
ASPARAGINYL-TRNA SYNTHETASE (EC 6.1.1.22)
(ASPARAGINE--TRNA LIGASE) (ASNRS) [Pyrococcus abyssi]
Length = 434
Score = 891 bits (2278), Expect = 0.0
Identities = 434/434 (100%), Positives = 434/434 (100%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF
Sbjct: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLD 120
ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLD
Sbjct: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLD 120
Query: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD 180
YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD
Sbjct: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD 180
Query: 181 KVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM 240
KVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM
Sbjct: 181 KVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM 240
Query: 241 KVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEW 300
KVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEW
Sbjct: 241 KVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEW 300
Query: 301 GDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIG 360
GDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIG
Sbjct: 301 GDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIG 360
Query: 361 GSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIR 420
GSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIR
Sbjct: 361 GSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIR 420
Query: 421 WATLFPRTPARIYP 434
WATLFPRTPARIYP
Sbjct: 421 WATLFPRTPARIYP 434
>pir||B71248 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus horikoshii
>gi|3256630|dbj|BAA29313.1| (AP000001) 434aa long
hypothetical asparaginyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 434
Score = 846 bits (2162), Expect = 0.0
Identities = 401/434 (92%), Positives = 424/434 (97%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
MIEK YCQ++KPELDGK+V+LAGWVY+NMRVGKKIFLWIRDSTGI+Q V+AKNVVGE+ F
Sbjct: 1 MIEKVYCQEVKPELDGKKVRLAGWVYTNMRVGKKIFLWIRDSTGIVQAVVAKNVVGEETF 60
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLD 120
E AKKLGRESSVIVEGIVKADERAPGGAEVHVEKL+VIQAVSEFPIPENPEQASPELLLD
Sbjct: 61 EKAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLEVIQAVSEFPIPENPEQASPELLLD 120
Query: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD 180
YRHLHIR+PK SAIM+VKETLIMAAREWLL++GWHEVFPPILVTGAVEGGATLFKLKYFD
Sbjct: 121 YRHLHIRTPKASAIMKVKETLIMAAREWLLKDGWHEVFPPILVTGAVEGGATLFKLKYFD 180
Query: 181 KVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM 240
K AYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM
Sbjct: 181 KYAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM 240
Query: 241 KVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEW 300
KVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI+ILQSKGV +EW
Sbjct: 241 KVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIDILQSKGVNVEW 300
Query: 301 GDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIG 360
GDD+GADEERVLT+EFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLA+DMLAPEGYGEIIG
Sbjct: 301 GDDLGADEERVLTEEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLASDMLAPEGYGEIIG 360
Query: 361 GSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIR 420
GS+RED+YDKL+ RI EEGMDPKDYEWYLDLR+YGSVPHSGFGLGVERLVAWVLKLDHIR
Sbjct: 361 GSQREDDYDKLLNRILEEGMDPKDYEWYLDLRRYGSVPHSGFGLGVERLVAWVLKLDHIR 420
Query: 421 WATLFPRTPARIYP 434
WA LFPRTPAR+YP
Sbjct: 421 WAALFPRTPARLYP 434
>emb|CAC11659.1| (AL445064) probable asparaginyl--tRNA synthetase [Thermoplasma
acidophilum]
Length = 429
Score = 432 bits (1098), Expect = e-120
Identities = 208/419 (49%), Positives = 288/419 (68%), Gaps = 3/419 (0%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
G +V + GWVY G F+ +RDS+GIIQ KN + EDV++T LG ESSV
Sbjct: 14 GSKVSIRGWVYRIRSSGGVTFVVVRDSSGIIQCTARKNELPEDVYDTISSLGIESSVEFH 73
Query: 76 GIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSAIM 135
G +K D R+P G E+ V+ +V Q FPI ++ + E LLD RHL +RS + ++++
Sbjct: 74 GTLKEDRRSPSGYEIAVDSFRVYQKNDVFPITKDQGE---EFLLDNRHLWLRSREFTSVL 130
Query: 136 RVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEA 195
+++ T+ + ++ G+++V P +V+ AVEGG+TLFK+ +F + YL+QSAQ YLE
Sbjct: 131 KIRSTIFRSFADFFYENGYYQVQTPFMVSTAVEGGSTLFKVDFFGEPIYLNQSAQFYLET 190
Query: 196 AIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTL 255
I+ LEKV+++ PSFRAEKSRTRRHLTE+WH E E AW+D ++M +EE ++ Y+V R
Sbjct: 191 MIYSLEKVFTIAPSFRAEKSRTRRHLTEYWHAEAEVAWIDNNEMMDIEERMIYYIVSRVT 250
Query: 256 ELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWGDDMGADEERVLTQE 315
E + E++M D LK +PPFPRI Y E I++ S G+ +++GDD+GADEER +T +
Sbjct: 251 EDNEDELKMLNRDPEVLKAMKPPFPRIRYSEIIKVANSIGLPLKYGDDLGADEERQITMK 310
Query: 316 FDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRI 375
+DRP FV YPK +K FYM DP +P +VL DMLAPEGYGEIIGGS+R NYD+L+QRI
Sbjct: 311 YDRPIFVTNYPKDLKPFYMPVDPENPGEVLNHDMLAPEGYGEIIGGSQRIWNYDELMQRI 370
Query: 376 KEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
+E +D Y WY+DLRKYGSVPHSGFGLG++RL W++ LD+IR A +PRT R P
Sbjct: 371 REANLDESAYYWYVDLRKYGSVPHSGFGLGLDRLAMWIMHLDNIREAIPYPRTIRRTKP 429
>sp|P39772|SYN_BACSU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|7437578|pir||B69591 asparagine--tRNA ligase (EC
6.1.1.22) asnS - Bacillus subtilis
>gi|1146247|gb|AAB38455.1| (L47709) asparaginyl-tRNA
synthetase [Bacillus subtilis]
>gi|2634654|emb|CAB14152.1| (Z99115) asparaginyl-tRNA
synthetase [Bacillus subtilis]
Length = 430
Score = 397 bits (1010), Expect = e-109
Identities = 201/420 (47%), Positives = 277/420 (65%), Gaps = 3/420 (0%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
G+ V + WV + GK FL +RD TG IQ V+ K V E +F+TAK + +E+S+ ++
Sbjct: 13 GEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIK 72
Query: 76 GIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSAIM 135
GIVK DER+P G E+ V ++VI +++PI P++ E L+D+RHL +RS + AIM
Sbjct: 73 GIVKEDERSPLGYELAVTDIEVIHEATDYPI--TPKEHGTEFLMDHRHLWLRSKRQHAIM 130
Query: 136 RVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEA 195
+++ +I A E+ EG+ +V PPIL A EG LF KYFD+ AYLSQS QLY+EA
Sbjct: 131 KIRNEIIRATYEFFNNEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYLSQSGQLYMEA 190
Query: 196 AIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTL 255
A L KV+S P+FRAEKS+T+RHL EFW +E E A+++ + ++V+E VS++VQ L
Sbjct: 191 AAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQENYVSFIVQSVL 250
Query: 256 ELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGV-KIEWGDDMGADEERVLTQ 314
+ K E+ D + L+ + PFPRI+YDEAIE L+ KG IEWGDD GA E + +
Sbjct: 251 KNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDFGAPHETAIAE 310
Query: 315 EFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQR 374
+D+P F+ YP +K FYM+ + VL AD++APEGYGEIIGGSER + + L R
Sbjct: 311 HYDKPVFITRYPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSERIHDMELLESR 370
Query: 375 IKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
+KE G+D Y+WY +LRKYGSVPHSGFGLG+ER VAW+ H+R FPR R+YP
Sbjct: 371 LKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAPHVRETIPFPRLLNRLYP 430
>dbj|BAB05415.1| (AP001512) asparaginyl-tRNA synthetase [Bacillus halodurans]
Length = 430
Score = 396 bits (1006), Expect = e-109
Identities = 199/419 (47%), Positives = 272/419 (64%), Gaps = 3/419 (0%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEG 76
+ V L W+ + GK FL +RD TG IQ V+ K VG++ F+ AK L +ESS+ V G
Sbjct: 14 QEVTLGAWLANKRSSGKIAFLQLRDGTGFIQGVVVKAEVGDEWFQKAKNLTQESSLYVTG 73
Query: 77 IVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSAIMR 136
IV+ DERAP G E+ V +I +++PI P++ E L+D+RHL IRS K A++R
Sbjct: 74 IVRKDERAPSGYELTVTSFDIIHEATDYPI--TPKEHGTEFLMDHRHLWIRSRKQHAVLR 131
Query: 137 VKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAA 196
++ +I A E+ G+ +V PPIL A EG LF KYFD+ A+LSQS QLY+EAA
Sbjct: 132 IRNEIIRATYEFFHENGFVKVDPPILTGSAPEGTTELFHTKYFDEDAFLSQSGQLYMEAA 191
Query: 197 IFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLE 256
+V+S P+FRAEKS+TRRHL EFW +E E A+++ + ++++E V+Y+VQ L+
Sbjct: 192 ALAFGRVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFVEFEESLEIQENYVAYIVQSVLK 251
Query: 257 LRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGV-KIEWGDDMGADEERVLTQE 315
E++ D + L++ + PFPRISYD+AI+ L KG IEWGDD GA E + +
Sbjct: 252 HCAIELKTLGRDTSVLESIQAPFPRISYDDAIKFLHEKGFDDIEWGDDFGAPHETAIAEH 311
Query: 316 FDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRI 375
FD+P F+ YP +K FYM+ DPN VL AD++APEGYGEIIGGS+R +YD L +R+
Sbjct: 312 FDKPVFITHYPTSLKPFYMEPDPNRDDVVLCADLIAPEGYGEIIGGSQRISDYDLLKKRL 371
Query: 376 KEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
+E + Y WYLDLRKYGSVPHSGFGLG+ER V W+ H+R FPR R+YP
Sbjct: 372 EEHDLSLDAYAWYLDLRKYGSVPHSGFGLGLERTVGWISGAGHVRETIPFPRLLNRLYP 430
>pir||S71074 asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactobacillus
delbrueckii subsp. bulgaricus
>gi|1495654|emb|CAA61604.1| (X89439) asparagine--tRNA
ligase [Lactobacillus delbrueckii]
Length = 432
Score = 370 bits (941), Expect = e-101
Identities = 187/419 (44%), Positives = 268/419 (63%), Gaps = 3/419 (0%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEG 76
+ V++ W+ GK +FL +RD T Q V+ KN V E+VFE AK L +E+S + G
Sbjct: 16 EEVRMHVWLTDKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75
Query: 77 IVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSAIMR 136
+ D R+ G E+ + L+V+ +PI ++ + LLD+RHL +RS + AIM+
Sbjct: 76 TIHEDARSHFGYEIQISDLEVVSNNEGYPITN--KEHGIDFLLDHRHLWLRSRRPFAIMQ 133
Query: 137 VKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAA 196
++ + A ++ EG+ + P+L+ A EG LF + YF+ AYLSQS QLY E
Sbjct: 134 IRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGEVG 193
Query: 197 IFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLE 256
K+++ P+FRAE S+TRRHLTEFW +E E AWM + + ++E +SY+V + LE
Sbjct: 194 AEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMHQDESLDLQERFLSYVVGQVLE 253
Query: 257 LRKKEIEMFRDDLTTLKNT-EPPFPRISYDEAIEILQSKGVKIEWGDDMGADEERVLTQE 315
+ E+ + DL L+ E + R+SYD+A+++LQ G +WGDD GA +E L+++
Sbjct: 254 HCEYELSILGRDLDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAFLSEQ 313
Query: 316 FDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRI 375
FDRPFF+ YP IK FYMK++P +P L AD+ APEGYGEI+GGSERE +YD L +I
Sbjct: 314 FDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREADYDTLKAQI 373
Query: 376 KEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
+E G++ DY WYLDLRKYGSVPHSGFG+G ER++AW+ KLDH+R A FPR R+ P
Sbjct: 374 EEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFPRMINRMQP 432
>pir||S71072 asparagine--tRNA ligase (EC 6.1.1.22) asnS1 - Lactobacillus
delbrueckii subsp. bulgaricus
Length = 432
Score = 369 bits (938), Expect = e-101
Identities = 186/419 (44%), Positives = 268/419 (63%), Gaps = 3/419 (0%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEG 76
+ V++ W+ GK +FL +RD T Q V+ KN V E+VFE AK L +E+S + G
Sbjct: 16 EEVRMHVWLADKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75
Query: 77 IVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSAIMR 136
+ D R+ G E+ + L+V+ +PI ++ + LLD+RHL +RS + AIM+
Sbjct: 76 TIHEDARSHFGYEIQISDLEVVSNNEGYPITN--KEHGIDFLLDHRHLWLRSRRPFAIMQ 133
Query: 137 VKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAA 196
++ + A ++ EG+ + P+L+ A EG LF + YF+ AYLSQS QLY E
Sbjct: 134 IRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGEVG 193
Query: 197 IFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLE 256
K+++ P+FRAE S+TRRHLTEFW +E E AWM + + ++E +SY+V + LE
Sbjct: 194 AEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMHQDESLDLQERFLSYVVGQVLE 253
Query: 257 LRKKEIEMFRDDLTTLKNT-EPPFPRISYDEAIEILQSKGVKIEWGDDMGADEERVLTQE 315
+ E+ + D+ L+ E + R+SYD+A+++LQ G +WGDD GA +E L+++
Sbjct: 254 HCEYELSILGRDVDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAFLSEQ 313
Query: 316 FDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRI 375
FDRPFF+ YP IK FYMK++P +P L AD+ APEGYGEI+GGSERE +YD L +I
Sbjct: 314 FDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREADYDTLKAQI 373
Query: 376 KEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
+E G++ DY WYLDLRKYGSVPHSGFG+G ER++AW+ KLDH+R A FPR R+ P
Sbjct: 374 EEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFPRMINRMQP 432
>sp|P54262|SYN_LACDE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|2145612|pir||S73326 asparagine--tRNA ligase (EC
6.1.1.22) asnS1 - Lactobacillus delbrueckii
>gi|1321875|emb|CAA61603.1| (X89438) asparagine--tRNA
ligase [Lactobacillus delbrueckii]
Length = 432
Score = 369 bits (938), Expect = e-101
Identities = 186/419 (44%), Positives = 268/419 (63%), Gaps = 3/419 (0%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEG 76
+ V++ W+ GK +FL +RD T Q V+ KN V E+VFE AK L +E+S + G
Sbjct: 16 EEVRMHVWLTDKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75
Query: 77 IVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSAIMR 136
+ D R+ G E+ + L+V+ +PI ++ + LLD+RHL +RS + AIM+
Sbjct: 76 TIHEDARSHFGYEIQISDLEVVSNNEGYPITN--KEHGIDFLLDHRHLWLRSRRPFAIMQ 133
Query: 137 VKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAA 196
++ + A ++ EG+ + P+L+ A EG LF + YF+ AYLSQS QLY E
Sbjct: 134 IRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGEVG 193
Query: 197 IFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLE 256
K+++ P+FRAE S+TRRHLTEFW +E E AWM + + ++E +SY+V + LE
Sbjct: 194 AEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMHQDESLDLQERFLSYVVGQVLE 253
Query: 257 LRKKEIEMFRDDLTTLKNT-EPPFPRISYDEAIEILQSKGVKIEWGDDMGADEERVLTQE 315
+ E+ + D+ L+ E + R+SYD+A+++LQ G +WGDD GA +E L+++
Sbjct: 254 HCEYELSILGRDVDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAFLSEQ 313
Query: 316 FDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRI 375
FDRPFF+ YP IK FYMK++P +P L AD+ APEGYGEI+GGSERE +YD L +I
Sbjct: 314 FDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREADYDTLKAQI 373
Query: 376 KEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
+E G++ DY WYLDLRKYGSVPHSGFG+G ER++AW+ KLDH+R A FPR R+ P
Sbjct: 374 EEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFPRMINRMQP 432
>sp|P54263|SYN_THETH ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1004327|emb|CAA62491.1| (X91009) asparaginyl-tRNA
synthetase [Thermus thermophilus]
Length = 438
Score = 353 bits (897), Expect = 2e-96
Identities = 193/440 (43%), Positives = 275/440 (61%), Gaps = 12/440 (2%)
Query: 4 KTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETA 63
+ + +I +D + V+L GW+Y GK FL +RD TG +Q + + V E VF A
Sbjct: 2 RVFIDEIARHVD-QEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREA 60
Query: 64 KKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVI-QAVSEFPIPENPEQASPELLLDYR 122
L +E+++ V G V+ D RAPGG E+ V L+V+ + E+PI P++ + L+D+R
Sbjct: 61 DHLPQETALRVWGRVREDRRAPGGFELAVRDLQVVSRPQGEYPI--GPKEHGIDFLMDHR 118
Query: 123 HLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD-K 181
HL +R + A+MR+++ L A E+ G+ PIL AVEG LF+++ FD +
Sbjct: 119 HLWLRHRRPFAVMRIRDELERAIHEFFGERGFLRFDAPILTPSAVEGTTELFEVELFDGE 178
Query: 182 VAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMK 241
AYLSQS QLY EA KV++ P+FRAE+S+TRRHL EFW +E E A+M + M
Sbjct: 179 KAYLSQSGQLYAEAGALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMA 238
Query: 242 VEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNT-EPPFPRISYDEAIEILQSKGVK--- 297
++EELVS++V R LE R +E+EM D L+ E +PR++Y EA+ ++ +
Sbjct: 239 LQEELVSFLVARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPE 298
Query: 298 ---IEWGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEG 354
+ +G+D GA E L++ FDRP FV YP IKAFYM+ DP DP VL D+L PEG
Sbjct: 299 VPPLPYGEDFGAPHEAALSRRFDRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLRPEG 358
Query: 355 YGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVL 414
YGEIIGGS+R + + L ++I+E G+ + Y+WYLDLR++GSVPHSGFGLG+ER VAW+
Sbjct: 359 YGEIIGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGSVPHSGFGLGLERTVAWIC 418
Query: 415 KLDHIRWATLFPRTPARIYP 434
L H+R A FPR R+ P
Sbjct: 419 GLAHVREAIPFPRMYTRMRP 438
>sp|O58776|SYD_PYRHO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437590|pir||G71094 aspartate--tRNA ligase (EC
6.1.1.12) - Pyrococcus horikoshii
>gi|3257434|dbj|BAA30117.1| (AP000004) 438aa long
hypothetical aspartyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 438
Score = 311 bits (788), Expect = 1e-83
Identities = 175/445 (39%), Positives = 264/445 (59%), Gaps = 18/445 (4%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M+ Y +I EL+GKRVK+AGWV +G F+WIRD GI+Q K V +++F
Sbjct: 1 MLRTHYSNEITEELNGKRVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVSQEIF 60
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPE---QASPEL 117
+ KL E ++VEGIV +A G EV EKL+VI ++ P+P +P +A +
Sbjct: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEVIPEKLEVISR-AKTPLPLDPTGKVKAELDT 119
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
LD R + +R+PKV AI +++ ++ A RE+ EG+ E+ P ++ A EGG LF LK
Sbjct: 120 RLDNRFMDLRNPKVMAIFKIRSSVFRAVREFFYSEGFIEIHTPKIIATATEGGTELFPLK 179
Query: 178 YFDKVAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD- 235
YF++ A+L+QS QLY + + GL+KV+ + P FRAE+ T RHL E W ++ E A+++
Sbjct: 180 YFERDAFLAQSPQLYKQMMMATGLDKVFEIAPIFRAEEHNTTRHLNEAWSIDAEMAFIEN 239
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKG 295
++M + E L+SY++ E +KE++ +L K PFPRI+YD+A+EIL G
Sbjct: 240 EGEVMDLLERLISYVINYVREHNEKELKTLEFELNEPKR---PFPRITYDKALEILSDLG 296
Query: 296 VKIEWGDDMGADEERVL-----TQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADML 350
+I WG+D+ + E++L E +F+Y YP K FY+ + P A D+
Sbjct: 297 KEIPWGEDIDTEGEKLLGKYMAENEGADLYFIYRYPSEAKPFYIMKYDEKPEVCRAFDL- 355
Query: 351 APEGYG-EIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERL 409
E G EI G +RE +D L+++IKE+G++PK +E+YL +YG PH GFGLG ERL
Sbjct: 356 --EYRGVEISSGGQREHRHDVLLEQIKEKGLNPKSFEFYLKAFEYGMPPHGGFGLGAERL 413
Query: 410 VAWVLKLDHIRWATLFPRTPARIYP 434
+ +L + +IR LFPR R+ P
Sbjct: 414 IMRMLDIGNIREVILFPRDRRRLVP 438
>pir||A75071 aspartyl-tRNA synthetase (asps) PAB0646 - Pyrococcus abyssi
(strain Orsay) >gi|5458382|emb|CAB49870.1| (AJ248286)
aspartyl-tRNA synthetase (aspS) [Pyrococcus abyssi]
Length = 438
Score = 305 bits (772), Expect = 8e-82
Identities = 170/445 (38%), Positives = 266/445 (59%), Gaps = 18/445 (4%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M+ Y +I EL+GK+VK+AGWV +G F+WIRD GI+Q K V +++F
Sbjct: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPE---QASPEL 117
+ KL E ++VEGIV +A G E+ EKL+VI + ++ P+P +P +A +
Sbjct: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVI-SKAKTPLPLDPTGKVKAELDT 119
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
LD R + +R+P+V +I +++ ++ A RE+ +EG+ E+ P ++ A EGG LF LK
Sbjct: 120 RLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK 179
Query: 178 YFDKVAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
YF+ A+L+QS QLY + + GL+KV+ + P FRAE+ T RHL E W ++ E A+++
Sbjct: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
Query: 237 -WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKG 295
++M + E L+ Y++ E +KE+++ +L K PFPRI+YDEA+EIL G
Sbjct: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKK---PFPRITYDEALEILSDLG 296
Query: 296 VKIEWGDDMGADEER-----VLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADML 350
+I WG+D+ + E+ +L E +F+Y YP K FY+ + + P A D+
Sbjct: 297 KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL- 355
Query: 351 APEGYG-EIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERL 409
E G EI G +RE +D LV++I+E+G++P+ +E+YL +YG PH GFGLG ERL
Sbjct: 356 --EYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERL 413
Query: 410 VAWVLKLDHIRWATLFPRTPARIYP 434
+ +L + +IR LFPR R+ P
Sbjct: 414 IMRMLDIGNIREVILFPRDRRRLVP 438
>sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2127776|pir||B64494 aspartate--tRNA ligase (EC
6.1.1.12) - Methanococcus jannaschii
>gi|1592183|gb|AAB99575.1| (U67596) aspartyl-tRNA
synthetase (aspS) [Methanococcus jannaschii]
Length = 438
Score = 302 bits (766), Expect = 4e-81
Identities = 169/435 (38%), Positives = 255/435 (57%), Gaps = 14/435 (3%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
Y DIKPE+DG+ V + GWV+S +GK IF+ +RD G +Q V K VG+++F KK
Sbjct: 12 YSADIKPEMDGQEVIIMGWVHSIRALGKIIFVILRDREGTVQIVAPKQKVGDELFSQIKK 71
Query: 66 LGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL---LDYR 122
LG E + V+G V A+E+AP G E+ +L+VI P+P +P + P L L+ R
Sbjct: 72 LGAEDVIAVKGKVIANEKAPNGFEILPLELEVINTAKR-PLPLDPAEKVPAELDTRLENR 130
Query: 123 HLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKV 182
L +R PKV AI +++ ++ + R L EG+ EV P LV EGG LF + YF++
Sbjct: 131 FLDLRRPKVQAIFKIRSEMLKSVRNTLYNEGFIEVNTPKLVASCTEGGTELFPISYFERE 190
Query: 183 AYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMK 241
A+L QS QLY + + GL++V+ + P FRAE+ TRRHL E +++E A+ D D M
Sbjct: 191 AFLGQSPQLYKQMLMATGLDRVFEIAPIFRAEEHNTRRHLNEATSIDIEMAFADDKDAMD 250
Query: 242 VEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPP--FPRISYDEAIEILQSKGVKIE 299
+ E++V E RKKEIE + PP F RI+YDEAI+I +KGV+I
Sbjct: 251 ILEKVVYNAFVDVYENRKKEIETLGIEFEL-----PPEKFDRITYDEAIDIANAKGVEIS 305
Query: 300 WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEII 359
WG+D+ + E+ + +E + +F+ +P I+ FY D +P A D++ + EI
Sbjct: 306 WGEDLSREAEKAIGEEMEGLYFITDWPSEIRPFYTMPDEKNPNICKAFDLMYKD--LEIS 363
Query: 360 GGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHI 419
G++R YD LV+ IK++G++P + +YL+ KYG PH+G+GLG +R + + ++I
Sbjct: 364 SGAQRIHLYDLLVENIKKKGLNPDGFTYYLEAFKYGMPPHAGWGLGADRFTMVLTQQENI 423
Query: 420 RWATLFPRTPARIYP 434
R LFPR R+ P
Sbjct: 424 RECVLFPRDRQRLTP 438
>gi|11498525 aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgidus]
>gi|3122883|sp|O29342|SYD_ARCFU ASPARTYL-TRNA SYNTHETASE
(ASPARTATE--TRNA LIGASE) (ASPRS) >gi|7437591|pir||H69364
aspartyl-tRNA synthetase (aspS) homolog - Archaeoglobus
fulgidus >gi|2649677|gb|AAB90318.1| (AE001040)
aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgidus]
Length = 430
Score = 298 bits (756), Expect = 6e-80
Identities = 167/436 (38%), Positives = 263/436 (60%), Gaps = 12/436 (2%)
Query: 4 KTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETA 63
+ Y D+KPE++G++V L GWV+ +G +F+ +RD GI+Q + + V + VF+ A
Sbjct: 2 RVYTADVKPEMEGQKVTLYGWVHEVRDLGGLVFILLRDREGIVQITLPRKFVSKQVFKLA 61
Query: 64 KKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIP-ENPEQASPEL--LLD 120
KK+ RES + V G V+ +E+APGG E+ E ++V+ ++ P+P E E+ EL LD
Sbjct: 62 KKIRRESVIAVTGEVRREEKAPGGVEIIPESIEVLNE-ADAPLPLEVTEKVPAELDTRLD 120
Query: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD 180
+R + +R P+V AI R++ ++ + RE+L EG+ EV P +V+ A EGG LF + YF+
Sbjct: 121 HRFMDLRRPRVQAIFRIRHQVMQSVREFLSEEGFIEVHTPKIVSTATEGGTELFPISYFE 180
Query: 181 KVAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDI 239
K A+L+QS QLY + + G EKV+ + P FRAE+ T RHL E +++E ++ D +
Sbjct: 181 KEAFLNQSPQLYKQVLMAAGFEKVFEIGPIFRAEEHNTTRHLNEAISIDIEMSFTDHNGV 240
Query: 240 MKVEEELVSYMVQRTLELRKKEIEMFRDDL-TTLKNTEPPFPRISYDEAIEILQSKGVKI 298
M V E L VQR E ++ E + L +L+ E PFPRI+YDEA EI KG +I
Sbjct: 241 MDVLERL----VQRVYEDVAEKCERYLGWLEVSLEIPELPFPRITYDEAREIAARKGEEI 296
Query: 299 EWGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEI 358
WG+D+ + +++ +E +F+ +P K FY P + R ++ G+ E+
Sbjct: 297 PWGEDLSTNALKLVGEEMGGLYFITDWPTESKPFYAM--PYEDRPEISKSFDLMHGWLEL 354
Query: 359 IGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDH 418
G++R YD LV+ IK +GM+P+ + +YL+ +YG PH+G+GLG ERL+ +L L +
Sbjct: 355 SSGAQRIHLYDMLVESIKAKGMEPESFGFYLEAFRYGMPPHAGWGLGAERLIMSMLGLKN 414
Query: 419 IRWATLFPRTPARIYP 434
+R A LFPR R+ P
Sbjct: 415 VREAVLFPRDRHRLVP 430
>sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2129413|pir||JC4352 aspartate--tRNA ligase (EC
6.1.1.12) - Pyrococcus sp >gi|1136773|dbj|BAA08115.1|
(D45167) aspartyl-tRNA synthetase [Pyrococcus sp.]
Length = 438
Score = 292 bits (740), Expect = 5e-78
Identities = 168/445 (37%), Positives = 260/445 (57%), Gaps = 18/445 (4%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M Y +I EL+G++VK+AGWV+ +G FLWIRD GI+Q K V ++F
Sbjct: 1 MYRTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDPELF 60
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPE---QASPEL 117
+ KL E V VEG+V +A G E+ EK+ V+ +E P+P +P +A +
Sbjct: 61 KLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNR-AETPLPLDPTGKVKAELDT 119
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
LD R + +R P+V AI +++ ++ A R++ G+ E+ P ++ A EGG LF +K
Sbjct: 120 RLDNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMK 179
Query: 178 YFDKVAYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM-D 235
YF++ A+L+QS QLY + + GL++V+ + P FRAE+ T RHL E W ++ E A++ D
Sbjct: 180 YFEEDAFLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIED 239
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKG 295
++M E LV++ + E KE+++ +L + + PFPR+SYD+A+EIL G
Sbjct: 240 EEEVMSFLERLVAHAINYVREHNAKELDILNFEL---EEPKLPFPRVSYDKALEILGDLG 296
Query: 296 VKIEWGDDMGADEERVLTQ-----EFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADML 350
+I WG+D+ + ER+L + E +F+Y YP K FY+ + N P A D+
Sbjct: 297 KEIPWGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDL- 355
Query: 351 APEGYG-EIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERL 409
E G EI G +RE +D LV++IKE+G++P+ +E+YL +YG PH GFGLG ER+
Sbjct: 356 --EYRGVEISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGLGAERV 413
Query: 410 VAWVLKLDHIRWATLFPRTPARIYP 434
+ +L L +IR LFPR R+ P
Sbjct: 414 IKQMLDLPNIREVILFPRDRRRLTP 438
>pdb|1B8A|A Chain A, Aspartyl-Trna Synthetase >gi|4388837|pdb|1B8A|B Chain B,
Aspartyl-Trna Synthetase
Length = 438
Score = 291 bits (738), Expect = 8e-78
Identities = 168/445 (37%), Positives = 260/445 (57%), Gaps = 18/445 (4%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M Y +I EL+G++VK+AGWV+ +G FLWIRD GI+Q K V ++F
Sbjct: 1 MYRTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDPELF 60
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPE---QASPEL 117
+ KL E V VEG+V +A G E+ EK+ V+ +E P+P +P +A +
Sbjct: 61 KLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNR-AETPLPLDPTGKVKAELDT 119
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
L+ R + +R P+V AI +++ ++ A R++ G+ E+ P ++ A EGG LF +K
Sbjct: 120 RLNNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMK 179
Query: 178 YFDKVAYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM-D 235
YF++ A+L++S QLY E + GL++V+ + P FRAE+ T RHL E W ++ E A++ D
Sbjct: 180 YFEEDAFLAESPQLYKEIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIED 239
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKG 295
++M E LV++ + E KE+++ +L + + PFPR+SYD+A+EIL G
Sbjct: 240 EEEVMSFLERLVAHAINYVREHNAKELDILNFEL---EEPKLPFPRVSYDKALEILGDLG 296
Query: 296 VKIEWGDDMGADEERVLTQ-----EFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADML 350
+I WG+D+ + ER+L + E +F+Y YP K FY+ + N P A D+
Sbjct: 297 KEIPWGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDL- 355
Query: 351 APEGYG-EIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERL 409
E G EI G +RE +D LV++IKE+G++P+ +E+YL +YG PH GFGLG ERL
Sbjct: 356 --EYRGVEISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGLGAERL 413
Query: 410 VAWVLKLDHIRWATLFPRTPARIYP 434
+ +L L +IR LFPR R+ P
Sbjct: 414 IKQMLDLPNIREVILFPRDRRRLTP 438
>sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437592|pir||A69128 aspartate--tRNA ligase (EC
6.1.1.12) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621273|gb|AAB84732.1| (AE000809)
aspartyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 437
Score = 287 bits (728), Expect = 1e-76
Identities = 162/433 (37%), Positives = 255/433 (58%), Gaps = 10/433 (2%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
Y +DI+PE+DG V + GWV+ +G IF+ +RD G+IQ + +D+F++ +K
Sbjct: 11 YSKDIEPEMDGDEVTVMGWVHEIRDLGGIIFVLLRDRDGLIQITAPSKKIEKDLFKSIRK 70
Query: 66 LGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQ---ASPELLLDYR 122
L +ES V G V+ +APGG E+ LKV+ +S+ P+P +P + A + LD R
Sbjct: 71 LKKESVVAFGGTVQESGKAPGGFEIIPSFLKVLN-ISKQPLPLDPTEKVKAEIDTRLDAR 129
Query: 123 HLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKV 182
L +R P VSAI ++K ++ + R +L +G+ E+ P LV A EGG LF + YF++
Sbjct: 130 FLDLRKPSVSAIFKIKSRMLHSVRVFLEEQGFLEINTPKLVASATEGGTELFPITYFERE 189
Query: 183 AYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMK 241
A+L QS QLY + + GL++V+ + P FRAE+ T RHL E +++EA+++D D+MK
Sbjct: 190 AFLGQSPQLYKQIMMSTGLDRVYEIAPIFRAEEHDTLRHLNEVISIDIEASFVDHEDVMK 249
Query: 242 VEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWG 301
+ E LV +++ E +E TL+ E PF R+ YDEA+E++ SKGV ++ G
Sbjct: 250 ILENLVVRVIEDVNEHCTDALETLG---RTLEVPETPFERLEYDEAVEMVNSKGVPMKHG 306
Query: 302 DDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGG 361
+D+ E+ L + D +F+ +P IK FY+ D +DP + A D++ + EI G
Sbjct: 307 EDLPRAAEKALGEIMDGYYFITSWPTAIKPFYVMPDEDDPERSHAFDLMYRD--LEISSG 364
Query: 362 SEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRW 421
+ R +D LV++IK +G++P +E YL +YG PH+G+GLG ER + L +IR
Sbjct: 365 AMRVHQHDLLVEKIKRQGLNPDSFESYLSAFEYGMPPHAGWGLGAERFNMTLTGLKNIRE 424
Query: 422 ATLFPRTPARIYP 434
LFPR R+ P
Sbjct: 425 TVLFPRDRRRLTP 437
>gi|6321807 Asparaginyl-tRNA synthetase; Ded81p [Saccharomyces cerevisiae]
>gi|731638|sp|P38707|SYNC_YEAST ASPARAGINYL-TRNA
SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
(ASNRS) >gi|626599|pir||S46775 hypothetical protein
YHR019c - yeast (Saccharomyces cerevisiae)
>gi|500693|gb|AAB68874.1| (U10399) Ded81p:
Asparaginyl-tRNA synthetase [Saccharomyces cerevisiae]
Length = 554
Score = 276 bits (698), Expect = 4e-73
Identities = 164/433 (37%), Positives = 249/433 (56%), Gaps = 21/433 (4%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
G+RVK++GW++ K IF+ +RD +G IQ V++ ++ + + L ES+V +
Sbjct: 129 GQRVKVSGWIHRLRSNKKVIFVVLRDGSGFIQCVLSGDLA---LAQQTLDLTLESTVTLY 185
Query: 76 G-IVKADE--RAPGGAEVHVEKLKVIQAV---SEFPIPENPEQASPELLLDYRHLHIRSP 129
G IVK E APGG E++V+ +V+ + + E + P LLLD RHL +R
Sbjct: 186 GTIVKLPEGKTAPGGVELNVDYYEVVGLAPGGEDSFTNKIAEGSDPSLLLDQRHLALRGD 245
Query: 130 KVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSA 189
+SA+M+V+ L+ + R E EV PP +V VEGG+TLFK+ Y+ + AYL+QS+
Sbjct: 246 ALSAVMKVRAALLKSVRRVYDEEHLTEVTPPCMVQTQVEGGSTLFKMNYYGEEAYLTQSS 305
Query: 190 QLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSY 249
QLYLE + L V+++ SFRAEKS TRRHL+E+ H+E E A++ D+++ E L+
Sbjct: 306 QLYLETCLASLGDVYTIQESFRAEKSHTRRHLSEYTHIEAELAFLTFDDLLQHIETLIVK 365
Query: 250 MVQRTLE--LRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI------EILQSKGVKIEWG 301
VQ LE + ++ + K + PF R+ Y +AI +I +G ++G
Sbjct: 366 SVQYVLEDPIAGPLVKQLNPN---FKAPKAPFMRLQYKDAITWLNEHDIKNEEGEDFKFG 422
Query: 302 DDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGG 361
DD+ ER +T P F+ +P IK+FYMK +DPR + D+L P GEI GG
Sbjct: 423 DDIAEAAERKMTDTIGVPIFLTRFPVEIKSFYMKRCSDDPRVTESVDVLMP-NVGEITGG 481
Query: 362 SEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRW 421
S R D+ D+L+ K EG+D Y W++D RKYG+ PH G+G+G ER++AW+ +R
Sbjct: 482 SMRIDDMDELMAGFKREGIDTDAYYWFIDQRKYGTCPHGGYGIGTERILAWLCDRFTVRD 541
Query: 422 ATLFPRTPARIYP 434
+L+PR R P
Sbjct: 542 CSLYPRFSGRCKP 554
>gb|AAK40519.1| Aspartyl-tRNA synthetase (aspS) [Sulfolobus solfataricus]
Length = 429
Score = 273 bits (691), Expect = 3e-72
Identities = 151/429 (35%), Positives = 254/429 (59%), Gaps = 11/429 (2%)
Query: 9 DIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGR 68
++ P+LDG VK+AGWV++ +G KIF+ +RD +GI Q V+ K G + ++ +G
Sbjct: 9 ELNPKLDGSEVKVAGWVHNVRNLGGKIFILLRDKSGIGQIVVEK---GNNAYDKVINIGL 65
Query: 69 ESSVIVEGIVKADERAPGGAEVHVEKLKVIQ-AVSEFPIPENPE-QASPELLLDYRHLHI 126
ES+++V G+VKAD RAP G EVH + ++++ A S P+ + +A + L R L +
Sbjct: 66 ESTIVVNGVVKADARAPNGVEVHAKDIEILSYARSPLPLDVTGKVKADIDTRLRERLLDL 125
Query: 127 RSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLS 186
R ++ A+++++ + + RE L + G+ EVF P ++ A EGGA LF + YF K A+L+
Sbjct: 126 RRLEMQAVLKIQSVAVKSFRETLYKHGFVEVFTPKIIASATEGGAQLFPVLYFGKEAFLA 185
Query: 187 QSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEEL 246
QS QLY E +E+V+ + P++RAE+S T HL+EF +++E A+ D DIM + E++
Sbjct: 186 QSPQLYKELLAGAIERVFEIAPAWRAEESDTPYHLSEFISMDVEMAFADYNDIMALIEQI 245
Query: 247 VSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWGDDMGA 306
+ M+ + E+++ T N P ++SY +AIE+L+SKGV I++GDD+G
Sbjct: 246 IYNMINDVKRECENELKILN---YTPPNVRIPIKKVSYSDAIELLKSKGVNIKFGDDIGT 302
Query: 307 DEERVLTQEFDRP-FFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSERE 365
E RVL E +FV +P + FY K+ ++P+ + D++ + EI+ GS R
Sbjct: 303 PELRVLYNELKEDLYFVTDWPWLSRPFYTKQKKDNPQLSESFDLIF--RWLEIVSGSSRN 360
Query: 366 DNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLF 425
+ L +K G++P+ +E++L YG PH+GFG+G+ R++ + L ++ F
Sbjct: 361 HVKEVLENSLKVRGLNPESFEFFLKWFDYGMPPHAGFGMGLARVMLMLTGLQSVKEVVPF 420
Query: 426 PRTPARIYP 434
PR R+ P
Sbjct: 421 PRDKKRLTP 429
>gb|AAD55420.1|AF181634_1 (AF181634) BcDNA.GH06451 [Drosophila melanogaster]
>gi|7298549|gb|AAF53768.1| (AE003661) BcDNA:GH06451 gene
product [Drosophila melanogaster]
Length = 558
Score = 272 bits (688), Expect = 6e-72
Identities = 162/430 (37%), Positives = 249/430 (57%), Gaps = 21/430 (4%)
Query: 18 RVKLAGWVYSNMRVGKK-IFLWIRDSTGIIQTVIAKNVVGEDVFET--AKKLGRESSVIV 74
RVK+ GWV+ R GK IF+ +RD TG +Q V+ + + +T A L ESSV++
Sbjct: 137 RVKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVL-----NDQLCQTYDALTLSTESSVVL 191
Query: 75 EGIVKA---DERAPGGAEVHVEKLKVIQAVSEFPIPEN-PEQASPELLLDYRHLHIRSPK 130
G +K + APGG E++V+ ++I E+A P++ LD RH+ IR
Sbjct: 192 FGTLKLVPEGKTAPGGHELNVDYWELIGLAPPGGADAILNEEAQPDVQLDNRHIMIRGEN 251
Query: 131 VSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQ 190
S +++++ + A R G++EV PP LV VEGG+TLFKLKYF + AYL+QS+Q
Sbjct: 252 TSKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQ 311
Query: 191 LYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYM 250
LYLE + L V++++ S+RAE+SRTRRHL E+ H+E E ++ D++ E+LV +
Sbjct: 312 LYLETCLPALGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLDRLEDLVCDV 371
Query: 251 VQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE------ILQSKGVKIEWGDDM 304
V R L+ + ++ K + PF R++Y++AI+ + + G E+G+D+
Sbjct: 372 VDRV--LKSPWGYLVKELNPDFKPPQKPFRRMNYEDAIKWLKENNVTKDDGTFYEFGEDI 429
Query: 305 GADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSER 364
ER +T + P + +P IK+FYM+ D R + D+L P GEI+GGS R
Sbjct: 430 PEAPERKMTDTINEPIMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLP-NVGEIVGGSMR 488
Query: 365 EDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATL 424
+ ++L++ K EG+DP+ Y WY D R YG++PH G+GLG+ER + W+L HIR L
Sbjct: 489 IYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRYHIREVCL 548
Query: 425 FPRTPARIYP 434
+PR R P
Sbjct: 549 YPRFLDRCRP 558
>pir||T39675 asparaginyl-trna synthetase - fission yeast (Schizosaccharomyces
pombe) >gi|3850088|emb|CAA21915.1| (AL033389)
asparaginyl-trna synthetase, cytoplasmic
[Schizosaccharomyces pombe]
Length = 568
Score = 268 bits (677), Expect = 1e-70
Identities = 164/433 (37%), Positives = 243/433 (55%), Gaps = 23/433 (5%)
Query: 18 RVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEG 76
RV++ GWV+ MR K I F+ +RD TG +Q V++ V ++ LG ES+V + G
Sbjct: 143 RVRVNGWVH-RMRTQKGIIFIILRDGTGFLQCVLSGKVYDRASYDFIN-LGPESTVCLYG 200
Query: 77 IVKA---DERAPGGAEVHVEKLKVIQAV----SEFPIPENPEQASPELLLDYRHLHIRSP 129
++K + APG E+ V+ +++ A F N E A P LLD RHL IR
Sbjct: 201 VIKELPEGKSAPGNHELVVDYYQILHAAPTGEEAFTNRLNAE-AEPSYLLDQRHLVIRGE 259
Query: 130 KVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSA 189
S++++V+ + A R+ EV PP +V VEGGATLFK Y+ + AYL+QS+
Sbjct: 260 TASSVLKVRARALRAMRDTFENLKMTEVTPPCMVQTQVEGGATLFKFNYYGQDAYLTQSS 319
Query: 190 QLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSY 249
QLYLEAA+ L V+++ SFRAEKS TRRHL+EF H+E E +++ + +++ EE +
Sbjct: 320 QLYLEAALPALGSVYTIQESFRAEKSLTRRHLSEFTHVEFELPFVNFGEFLEIIEEFICQ 379
Query: 250 MVQRTLE--LRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE------ILQSKGVKIEWG 301
+ R L+ + I+ D PF R+SY++AI+ IL +G + ++G
Sbjct: 380 TIDRLLDDPIATPLIKQLNPDFV---KPSRPFMRLSYEDAIKYLNEHNILTPEGEQHKFG 436
Query: 302 DDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGG 361
DD+ ER +T + +RP F+ +P IK+FYMK + P + D L P GEI+GG
Sbjct: 437 DDIAEAAERKMTDQINRPIFLTYFPLEIKSFYMKRVVDRPELTESVDCLMP-NVGEIVGG 495
Query: 362 SEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRW 421
S R + +L+ K EG+DP Y W+ + RKYG+ H G GLG+ER +AW+ +R
Sbjct: 496 SMRISDIQELLAAYKREGIDPAPYYWFTEQRKYGTTEHGGCGLGLERFLAWLCDRYTVRE 555
Query: 422 ATLFPRTPARIYP 434
LFPR R P
Sbjct: 556 CCLFPRFTERCTP 568
>sp|Q19722|SYN_CAEEL PROBABLE ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA
LIGASE) (ASNRS) >gi|7499656|pir||T21253 hypothetical
protein F22D6.3 - Caenorhabditis elegans
>gi|3876241|emb|CAA95808.1| (Z71262) predicted using
Genefinder~Similarity to Brugia asparaginyl-tRNA
synthetase (SW:63KD_BRUMA), contains similarity to Pfam
domain: PF00152 (tRNA synthetases class II (D, K and
N)), Score=452.1, E-value=1.6e-132, N=1~cDNA EST
EMBL:Z14941 comes fr>
Length = 545
Score = 266 bits (673), Expect = 3e-70
Identities = 171/431 (39%), Positives = 233/431 (53%), Gaps = 20/431 (4%)
Query: 17 KRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
+RV + WV+ R GK + FL +RD G +Q V+ + A L E+SV V
Sbjct: 122 QRVSIKAWVHRLRRQGKSLMFLVLRDGYGFLQCVLNDKLCQS---YDAVTLSTETSVQVY 178
Query: 76 GIVKA---DERAPGGAEVHVEKLKVIQAVSEFPIPEN-PEQASPELLLDYRHLHIRSPKV 131
GI+KA + AP G E+ V+ +VI I E A +++LD RHL IR
Sbjct: 179 GIIKALPDGKSAPDGHELTVDYWEVIGKAPAGGIDNVLNESAGVDVMLDNRHLVIRGENA 238
Query: 132 SAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQL 191
S I+R++ A R+ G+ EV PP LV VEGG+TLF L Y+ + AYL+QS+QL
Sbjct: 239 SRILRIRAAATRAMRDHFFAAGYTEVAPPTLVQTQVEGGSTLFGLDYYGEPAYLTQSSQL 298
Query: 192 YLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMV 251
YLE L V+ ++ S+RAEKSRTRRHL+E+ H+E E A++ +M E LV V
Sbjct: 299 YLETCNAALGDVYCISQSYRAEKSRTRRHLSEYQHVEAECAFITFDQLMDRIEALVCDTV 358
Query: 252 QRTL--ELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSK------GVKIEWGDD 303
R L + K IE K PF R+ Y EAIE LQ G K +G+D
Sbjct: 359 DRLLADPVTKSLIEFVNPG---YKAPARPFKRMPYKEAIEWLQKNDVRNEMGEKFVYGED 415
Query: 304 MGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSE 363
+ ER +T P + +P IKAFYM +D + D+L P G GEI+GGS
Sbjct: 416 IAEAAERRMTDTIGVPILLNRFPHGIKAFYMPRCADDNELTESVDLLMP-GVGEIVGGSM 474
Query: 364 REDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWAT 423
R D+L+ ++ G+D K+Y WY+D RKYGSVPH G+GLG+ER + W+ +HIR
Sbjct: 475 RIWKEDQLLAAFEKGGLDSKNYYWYMDQRKYGSVPHGGYGLGLERFICWLTDTNHIRDVC 534
Query: 424 LFPRTPARIYP 434
L+PR R P
Sbjct: 535 LYPRFVGRCAP 545
>gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
>gi|3915059|sp|O43776|SYN_HUMAN ASPARAGINYL-TRNA
SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
(ASNRS) >gi|2764505|emb|CAA04008.1| (AJ000334)
asparaginyl-tRNA synthetase [Homo sapiens]
>gi|3894218|dbj|BAA34600.1| (D84273) Asparaginyl tRNA
Synthetase [Homo sapiens]
Length = 548
Score = 265 bits (671), Expect = 6e-70
Identities = 161/431 (37%), Positives = 244/431 (56%), Gaps = 19/431 (4%)
Query: 16 GKRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIV 74
G+RVK+ GWV+ R GK + FL +RD TG +Q V+A + L ESSV V
Sbjct: 125 GQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQ---CYNGVLLSTESSVAV 181
Query: 75 EGIVKAD---ERAPGGAEVHVEKLKVIQAVSEFPIPEN--PEQASPELLLDYRHLHIRSP 129
G++ ++APGG E+ + ++I ++ +N E++ ++ L+ RH+ IR
Sbjct: 182 YGMLNLTPKGKQAPGGHELSCDFWELI-GLAPAGGADNLINEESDVDVQLNNRHMMIRGE 240
Query: 130 KVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSA 189
+S I++ + + R+ G++EV PP LV VEGGATLFKL YF + A+L+QS+
Sbjct: 241 NMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSS 300
Query: 190 QLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSY 249
QLYLE + L V+ + S+RAE+SRTRRHL E+ H+E E ++ D++ E+LV
Sbjct: 301 QLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCD 360
Query: 250 MVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVK------IEWGDD 303
+V R L+ I + + + PF R++Y +AI L+ VK E+G+D
Sbjct: 361 VVDRILKSPAGSI--VHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGED 418
Query: 304 MGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSE 363
+ ER++T + P + +P IK+FYM+ P D R + D+L P GEI+GGS
Sbjct: 419 IPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMP-NVGEIVGGSM 477
Query: 364 REDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWAT 423
R + ++++ K EG+DP Y WY D RKYG+ PH G+GLG+ER + W+L HIR
Sbjct: 478 RIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVC 537
Query: 424 LFPRTPARIYP 434
L+PR R P
Sbjct: 538 LYPRFVQRCTP 548
>gi|11426051 asparaginyl-tRNA synthetase [Homo sapiens]
Length = 572
Score = 265 bits (671), Expect = 6e-70
Identities = 161/431 (37%), Positives = 244/431 (56%), Gaps = 19/431 (4%)
Query: 16 GKRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIV 74
G+RVK+ GWV+ R GK + FL +RD TG +Q V+A + L ESSV V
Sbjct: 149 GQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQ---CYNGVLLSTESSVAV 205
Query: 75 EGIVKAD---ERAPGGAEVHVEKLKVIQAVSEFPIPEN--PEQASPELLLDYRHLHIRSP 129
G++ ++APGG E+ + ++I ++ +N E++ ++ L+ RH+ IR
Sbjct: 206 YGMLNLTPKGKQAPGGHELSCDFWELI-GLAPAGGADNLINEESDVDVQLNNRHMMIRGE 264
Query: 130 KVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSA 189
+S I++ + + R+ G++EV PP LV VEGGATLFKL YF + A+L+QS+
Sbjct: 265 NMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSS 324
Query: 190 QLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSY 249
QLYLE + L V+ + S+RAE+SRTRRHL E+ H+E E ++ D++ E+LV
Sbjct: 325 QLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCD 384
Query: 250 MVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVK------IEWGDD 303
+V R L+ I + + + PF R++Y +AI L+ VK E+G+D
Sbjct: 385 VVDRILKSPAGSI--VHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGED 442
Query: 304 MGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSE 363
+ ER++T + P + +P IK+FYM+ P D R + D+L P GEI+GGS
Sbjct: 443 IPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMP-NVGEIVGGSM 501
Query: 364 REDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWAT 423
R + ++++ K EG+DP Y WY D RKYG+ PH G+GLG+ER + W+L HIR
Sbjct: 502 RIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVC 561
Query: 424 LFPRTPARIYP 434
L+PR R P
Sbjct: 562 LYPRFVQRCTP 572
>sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|11271301|pir||T48900 aspartate--tRNA ligase (EC
6.1.1.12) [imported] - Halobacterium salinarum
>gi|2209068|dbj|BAA20527.1| (D82887) aspartyl-tRNA
synthetase [Halobacterium salinarum]
>gi|10580067|gb|AAG19001.1| (AE005000) aspartyl-tRNA
synthetase; AspS [Halobacterium sp. NRC-1]
Length = 436
Score = 260 bits (658), Expect = 2e-68
Identities = 154/443 (34%), Positives = 255/443 (56%), Gaps = 16/443 (3%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M+E+TY +D+ P+ DG+ +AG V+ +G +F+ +RD+TG +Q V+AK D+F
Sbjct: 1 MLERTYIEDVTPDDDGEDTTIAGHVHELRDLGGILFVIVRDATGRLQ-VVAKEDDTPDLF 59
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL-- 118
ETA+ L E V V G ++A ++APGG E+ +L V+ ++ P E + +L
Sbjct: 60 ETAEGLSSEDVVQVTGTLEASDQAPGGVELAPTELTVVSEATDVPSIEISKDVDADLSTR 119
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
LD RHL +R P A+ ++ + A +W + EV P L T EGGA LF + Y
Sbjct: 120 LDERHLDVRKPSTKAVFSLRSKAMGAMTDWFYDNRFEEVDTPELSTAGAEGGADLFPVVY 179
Query: 179 FDKVAYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM-DL 236
+DK AYLSQS QLY + + G+++++ + +FRAE T RH++E ++E ++ D
Sbjct: 180 YDKEAYLSQSPQLYKQILVASGVDRLFEVGHAFRAEDFGTSRHVSEIAMFDVELGYVEDH 239
Query: 237 WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGV 296
D+M V+EE + + ++ +E ++E++ DL+ E FPRI+++EA EIL +
Sbjct: 240 HDVMDVQEESLRHTIRHVVEHAQRELDELGSDLSV---PEADFPRITFEEAREILADEYD 296
Query: 297 KIEWGD-DMGADEERVLTQEFDRP----FFVYGYPKHIKAFYMKEDPNDPRKVLAADMLA 351
+ D D+ ER+L + F+ FV GYP + FY ++D + L
Sbjct: 297 HVPEDDNDLDTKGERLLGEYFEEQGHPAVFVVGYPD--EKFYYRQDVDGDDVASRKFDLL 354
Query: 352 PEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVA 411
G E+ G +RE + ++L +++E+G++P+++E+YLD +YG PH G+GLG++RL+
Sbjct: 355 YRGQ-ELSSGGQREHDIERLTAKMREQGVEPENFEFYLDAFRYGVPPHGGYGLGIDRLIQ 413
Query: 412 WVLKLDHIRWATLFPRTPARIYP 434
+ LD+I+ A LFPR P R+ P
Sbjct: 414 QLAGLDNIKEAILFPRDPDRLEP 436
>emb|CAC12075.1| (AL445066) aspartyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 428
Score = 258 bits (653), Expect = 8e-68
Identities = 149/435 (34%), Positives = 242/435 (55%), Gaps = 13/435 (2%)
Query: 4 KTYCQDIKPELDGKRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKNVVGEDVFET 62
+TY ++ DG +V + GW+ R+ K I FL IRD+TG IQ + E +
Sbjct: 3 RTYIDTLRDHEDGAKVVVYGWM-QEARIMKNISFLMIRDNTGTIQATFKND---EATLDI 58
Query: 63 AKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVI-QAVSEFPIPE-NPEQASPELLLD 120
K++ RES V V+G V + G E+ + ++ +A + P+P +P QA E L+
Sbjct: 59 IKRINRESIVRVDGSVNKKSISKAGIEISGTSISIVNEAEAPLPLPVVDPVQADLETRLN 118
Query: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD 180
R + +R +SAI R++ L+ R++L + + EV P +V A EGG+ LF ++YF+
Sbjct: 119 SRFMDLRKRNISAIFRIESALLWGIRQYLHSQKFIEVHTPKIVAAATEGGSDLFPVRYFE 178
Query: 181 KVAYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDI 239
K AYL+QS QLY E + G ++V+ + P+FRAE+ T RHL EF +++E ++ D D
Sbjct: 179 KDAYLNQSPQLYKEVLMSAGFDRVFEVGPAFRAEEHNTTRHLNEFTSIDIEMSFADHNDA 238
Query: 240 MKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIE 299
M + E + ++ + ++ E ++ E PFPRI+Y++ I++LQ G+
Sbjct: 239 MAMLENAIRSGIENAVRENAEDFESLGISISV---PETPFPRITYEQCIDLLQKDGIDFT 295
Query: 300 WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEII 359
+GDD D+ R + F +F+ +P ++ FY DPR + D+ E E+
Sbjct: 296 FGDDFSPDQLRTIGSRFSGFYFITEWPSSVRPFYTMPKSEDPRLTNSFDLQYREI--EVT 353
Query: 360 GGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHI 419
G++R + L+QR E+ +D K +++Y+D KYG PH+G+GLG+ERL +L L++I
Sbjct: 354 SGAQRVHDPKMLIQRFNEKKLDVKSFQFYVDAFKYGMPPHAGWGLGLERLTMILLGLNNI 413
Query: 420 RWATLFPRTPARIYP 434
R TLFPR RI P
Sbjct: 414 RETTLFPRDRTRIVP 428
>sp|Q9Y9U7|SYD_AERPE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
Length = 442
Score = 257 bits (649), Expect = 2e-67
Identities = 159/450 (35%), Positives = 259/450 (57%), Gaps = 24/450 (5%)
Query: 1 MIEKTYCQDI---KPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGE 57
M++ + DI K L G RV++ GW Y +G+ F+ +RD +G+IQ + + E
Sbjct: 1 MLKDRFIADIIASKESLVGGRVRVCGWAYRIRDLGRLKFILVRDRSGVIQATVKRGESPE 60
Query: 58 DVFETAKKLGRESSVIVEGIVKADERAPG--GAEVHVEKLKVIQAVSEFPIP---ENPEQ 112
D A+ L ES V VEG ++ +AP G EV VE+L+V+ E P+P E E+
Sbjct: 61 DALRAAEDLKLESVVCVEGELR---QAPTREGVEVKVERLEVLSTPVE-PLPLEVEGSEK 116
Query: 113 ASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT 172
AS L YR L IR+P VSAI ++ + R++ +G+ E+F P +V E GA
Sbjct: 117 ASLPTRLKYRWLDIRNPMVSAIFELEAMVAKVFRDYYWSQGFVEIFTPKIVAAGTESGAE 176
Query: 173 LFKLKYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEA 231
+F + YFDK A+L+QS Q Y + A I GLE+V+ + P FRAE T RHL E+ L++E
Sbjct: 177 VFPVVYFDKTAFLAQSPQFYKQFAVIAGLERVFEIGPVFRAEPHHTSRHLNEYHSLDIEV 236
Query: 232 AWMDLW-DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEI 290
+++ + D+M E + +V+ E ++ +E++ +L + + P+I +A EI
Sbjct: 237 GFIESYNDVMNYVEGFMRAIVRMLEEDGRRVLELYGVELPRIPASG--IPKIPLRKAYEI 294
Query: 291 LQSK-GVKIEWGDDMGADEERVLT----QEFDRPF-FVYGYPKHIKAFYMKEDPNDPRKV 344
L+ K G K+E+G+D+ ++ ER++ +E D F F+ YP ++ FY ++P
Sbjct: 295 LEEKYGKKVEYGEDLDSEGERLMGAYAGEELDSDFVFIVEYPWKVRPFYTMRKDDEPSWT 354
Query: 345 LAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGL 404
+ D+L G EI+ G +RE Y +L++ ++++G+D + +++YLD K+G+ PH G G+
Sbjct: 355 YSFDLLY-RGL-EIVTGGQREHRYHRLLENLRDKGLDAESFQFYLDFFKHGAPPHGGAGM 412
Query: 405 GVERLVAWVLKLDHIRWATLFPRTPARIYP 434
G+ER+V LKL++IR A + PR RI P
Sbjct: 413 GLERIVMQTLKLENIREARMLPRDTERITP 442
>pir||C72527 probable aspartyl-tRNA synthetase APE2192 - Aeropyrum pernix
(strain K1) >gi|5105891|dbj|BAA81203.1| (AP000063) 421aa
long hypothetical aspartyl-tRNA synthetase [Aeropyrum
pernix]
Length = 421
Score = 249 bits (629), Expect = 5e-65
Identities = 151/429 (35%), Positives = 249/429 (57%), Gaps = 21/429 (4%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGIV 78
+++ GW Y +G+ F+ +RD +G+IQ + + ED A+ L ES V VEG +
Sbjct: 1 MRVCGWAYRIRDLGRLKFILVRDRSGVIQATVKRGESPEDALRAAEDLKLESVVCVEGEL 60
Query: 79 KADERAPG--GAEVHVEKLKVIQAVSEFPIP---ENPEQASPELLLDYRHLHIRSPKVSA 133
+ +AP G EV VE+L+V+ E P+P E E+AS L YR L IR+P VSA
Sbjct: 61 R---QAPTREGVEVKVERLEVLSTPVE-PLPLEVEGSEKASLPTRLKYRWLDIRNPMVSA 116
Query: 134 IMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYL 193
I ++ + R++ +G+ E+F P +V E GA +F + YFDK A+L+QS Q Y
Sbjct: 117 IFELEAMVAKVFRDYYWSQGFVEIFTPKIVAAGTESGAEVFPVVYFDKTAFLAQSPQFYK 176
Query: 194 E-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW-DIMKVEEELVSYMV 251
+ A I GLE+V+ + P FRAE T RHL E+ L++E +++ + D+M E + +V
Sbjct: 177 QFAVIAGLERVFEIGPVFRAEPHHTSRHLNEYHSLDIEVGFIESYNDVMNYVEGFMRAIV 236
Query: 252 QRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSK-GVKIEWGDDMGADEER 310
+ E ++ +E++ +L + + P+I +A EIL+ K G K+E+G+D+ ++ ER
Sbjct: 237 RMLEEDGRRVLELYGVELPRIPASG--IPKIPLRKAYEILEEKYGKKVEYGEDLDSEGER 294
Query: 311 VLT----QEFDRPF-FVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSERE 365
++ +E D F F+ YP ++ FY ++P + D+L G EI+ G +RE
Sbjct: 295 LMGAYAGEELDSDFVFIVEYPWKVRPFYTMRKDDEPSWTYSFDLLY-RGL-EIVTGGQRE 352
Query: 366 DNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLF 425
Y +L++ ++++G+D + +++YLD K+G+ PH G G+G+ER+V LKL++IR A +
Sbjct: 353 HRYHRLLENLRDKGLDAESFQFYLDFFKHGAPPHGGAGMGLERIVMQTLKLENIREARML 412
Query: 426 PRTPARIYP 434
PR RI P
Sbjct: 413 PRDTERITP 421
>sp|P43829|SYN_HAEIN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1073865|pir||B64115 asparagine--tRNA ligase (EC
6.1.1.22) - Haemophilus influenzae (strain Rd KW20)
>gi|1574761|gb|AAC22949.1| (U32810) asparaginyl-tRNA
synthetase (asnS) [Haemophilus influenzae Rd]
Length = 477
Score = 244 bits (616), Expect = 2e-63
Identities = 161/450 (35%), Positives = 240/450 (52%), Gaps = 41/450 (9%)
Query: 16 GKRVKLAGWVYS--NMRVGKKIFLWIRDSTGI--IQTVIAKNVVGEDVFETAKKLGRESS 71
G+ V + GWV + + + G FL + D + IQ +I ++ E+ +L S
Sbjct: 28 GETVTVRGWVRTRRDSKAGLS-FLAVYDGSCFDPIQAIINNDI--ENYESEILRLTTGCS 84
Query: 72 VIVEGIVKADERAPGGAEVHVEKLKVIQAVSE-FPIPENPEQASPELLLDYRHLHIRSPK 130
VIV G V E+ EK++V V + P ++ S E L + HL R+
Sbjct: 85 VIVTGKVVESPAEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIEYLREVAHLRPRTNI 144
Query: 131 VSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK------------- 177
+ A+ RV+ L A + +G++ V P++ EG +F++
Sbjct: 145 IGAVARVRHCLSQAIHRFFHEQGFYWVATPLITASDTEGAGEMFRVSTLDLENLPRSENG 204
Query: 178 -------YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELE 230
+F K ++L+ S QL E L K+++ P+FRAE S T RHL EFW +E E
Sbjct: 205 KVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTTRHLAEFWMVEPE 264
Query: 231 AAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMF-----RDDLTTLKN-TEPPFPRISY 284
A+ L D K+ E+++ Y+ + L RK +++ F +D +T L+N F +I Y
Sbjct: 265 VAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDY 324
Query: 285 DEAIEILQSKGVKIE----WGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPN 339
+AI++L G K E WG D+ ++ ER L +E F P V YPK IKAFYM+ + +
Sbjct: 325 TDAIDVLLKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLN-D 383
Query: 340 DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPH 399
D + V A D+LAP G GEIIGGS+RE+ + L +R++E G++P DY WY DLRKYGSVPH
Sbjct: 384 DEKTVAAMDVLAP-GIGEIIGGSQREERLEVLDKRMEEMGLNPDDYWWYRDLRKYGSVPH 442
Query: 400 SGFGLGVERLVAWVLKLDHIRWATLFPRTP 429
SGFGLG ERL+ +V + +IR FPR P
Sbjct: 443 SGFGLGFERLIVYVTGVQNIRDVIPFPRAP 472
>pir||F82540 asparaginyl-tRNA synthetase XF2563 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107777|gb|AAF85360.1|AE004064_2
(AE004064) asparaginyl-tRNA synthetase [Xylella
fastidiosa]
Length = 466
Score = 243 bits (615), Expect = 2e-63
Identities = 161/454 (35%), Positives = 241/454 (52%), Gaps = 47/454 (10%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTG----IIQTVIAKNVVGEDVFET-AKKLGRES 70
G V + GWV + R K ++ S G IQ V ++ +ET +KL
Sbjct: 17 GSEVTVRGWVRTR-RDSKAGLSFVSVSDGSCFAAIQVVTPAHLPN---YETEVRKLTTGC 72
Query: 71 SVIVEGIVKADERAPGGAEVHVEKLKVIQAVSE---FPIPENPEQASPELLLDYRHLHIR 127
+VIV G + E+ + ++V+ V + +PI P+Q S E L + HL R
Sbjct: 73 AVIVIGTLAPSLGQGQQFEIQAQSIEVVGWVEDPETYPI--QPKQHSLEFLREVAHLRPR 130
Query: 128 SPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK---------- 177
+ A+ R++ L A + G++ + PI+ T EG +F++
Sbjct: 131 TNLFGAVARIRHCLSQAVHRFFHENGYYWITTPIITTSDAEGAGQMFRVSTLDLVNLPRT 190
Query: 178 ----------YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHL 227
+F K +L+ S QL +EA L KV++ P+FRAE S T RHL EFW +
Sbjct: 191 ETGGIDFSHDFFGKETFLTVSGQLNVEAYALALSKVYTFGPTFRAENSHTPRHLAEFWMI 250
Query: 228 ELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMF--RDDLTTLKNTE----PPFPR 281
E E A+ DL + +V E+ + ++ + LE R ++ R + TT+ E PF R
Sbjct: 251 EPEIAFADLAEDARVAEQFLKFLFKTVLEERTDDLAFITERVEKTTISKLEGFIKSPFER 310
Query: 282 ISYDEAIEILQSKGVK----IEWGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKE 336
I Y +AI++L+ G K +EWG D+ + ER LT++ RP V YP+HIKAFYM+
Sbjct: 311 IEYTDAIKLLERSGKKFDFPVEWGLDLQTEHERWLTEKHIGRPVVVTNYPEHIKAFYMRL 370
Query: 337 DPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGS 396
+ +D + V A D+LAP G GEIIGGS+RE+ + L R+ + G+DP Y+WY D R+YGS
Sbjct: 371 N-DDGKTVAAMDVLAP-GIGEIIGGSQREERLEMLDIRMAQFGLDPTHYQWYRDFRRYGS 428
Query: 397 VPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPA 430
VPH+GFGLG ERL+ +V L +IR A +PR P+
Sbjct: 429 VPHAGFGLGFERLMVYVCGLSNIRDAIPYPRAPS 462
>pir||A28209 60K filarial antigen - nematode (Brugia malayi)
>gi|156053|gb|AAA27849.1| (J03266) 63kd antigen [Brugia
malayi]
Length = 548
Score = 242 bits (611), Expect = 6e-63
Identities = 156/431 (36%), Positives = 226/431 (52%), Gaps = 20/431 (4%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWI-RDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
+RV + GW++ R GK + +I RD TG +Q ++ + A + E +V +
Sbjct: 125 ERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLLMDKLCQT---YDALTVNTECTVEIY 181
Query: 76 GIVKA---DERAPGGAEVHVEKLKVIQAVSEFPIPEN-PEQASPELLLDYRHLHIRSPKV 131
G +K + AP G E+ + K+I I E+AS + +LD RHL IR
Sbjct: 182 GAIKEVPEGKEAPNGHELIADFWKIIGNAPSGGIDNVLNEEASVDKMLDNRHLVIRGENA 241
Query: 132 SAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQL 191
+A++R++ A RE G+ EV PP LV VEGG+TLF L YF + ++L+QS+QL
Sbjct: 242 AALLRLRAAATRAMREHFYNAGYVEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQL 301
Query: 192 YLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMV 251
YLE I L V+ + K L E+ H+E E ++ L D+M+ EELV V
Sbjct: 302 YLETCIPTLGDVFLHCSVLQGGKISHSSTLAEYAHVEAECPFITLDDLMEKIEELVCDTV 361
Query: 252 QRTL--ELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIE------WGDD 303
R L E KK +E + E PF R+ Y +AI+ LQ V+ E +G+D
Sbjct: 362 DRLLADEEAKKLLEHIN---PKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGED 418
Query: 304 MGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSE 363
+ ER +T ++P + +P IKAFYM+ D D + D+L P G GEI+GGS
Sbjct: 419 IAEAAERFMTDTINKPILLNRFPSEIKAFYMQRDAKDNTLTESVDLLMP-GVGEIVGGSM 477
Query: 364 REDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWAT 423
R +D+L + K +DPK Y WYLD R YG+ PH G+GLG+ER + W+ +HIR
Sbjct: 478 RIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLGLERFICWLTNTNHIRDVC 537
Query: 424 LFPRTPARIYP 434
L+PR R P
Sbjct: 538 LYPRFVGRCVP 548
>sp|P10723|SYN_BRUMA ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
(ASNRS) (POTENTIALLY PROTECTIVE 63 KD ANTIGEN)
>gi|627105|pir||A54510 63K antigen - nematode (Brugia
malayi) >gi|156057|gb|AAA27852.1| (J03971) 63 kd antigen
[Brugia malayi]
Length = 548
Score = 242 bits (610), Expect = 8e-63
Identities = 156/431 (36%), Positives = 226/431 (52%), Gaps = 20/431 (4%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWI-RDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
+RV + GW++ R GK + +I RD TG +Q ++ + A + E +V +
Sbjct: 125 ERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLLMDKLCQT---YDALTVNTECTVEIY 181
Query: 76 GIVKA---DERAPGGAEVHVEKLKVIQAVSEFPIPEN-PEQASPELLLDYRHLHIRSPKV 131
G +K + AP G E+ + K+I I E+AS + +LD RHL IR
Sbjct: 182 GAIKEVPEGKEAPNGHELIADFWKIIGNAPPGGIDNVLNEEASVDKMLDNRHLVIRGENA 241
Query: 132 SAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQL 191
+A++R++ A RE G+ EV PP LV VEGG+TLF L YF + ++L+QS+QL
Sbjct: 242 AALLRLRAAATRAMREHFYNAGYLEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQL 301
Query: 192 YLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMV 251
YLE I L V+ + K L E+ H+E E ++ L D+M+ EELV V
Sbjct: 302 YLETCIPTLGDVFLHCSVLQGGKISHSSTLAEYAHVEAECPFITLDDLMEKIEELVCDTV 361
Query: 252 QRTL--ELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIE------WGDD 303
R L E KK +E + E PF R+ Y +AI+ LQ V+ E +G+D
Sbjct: 362 DRLLADEEAKKLLEHIN---PKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGED 418
Query: 304 MGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSE 363
+ ER +T ++P + +P IKAFYM+ D D + D+L P G GEI+GGS
Sbjct: 419 IAEAAERFMTDTINKPILLNRFPSEIKAFYMQRDAQDNTLTESVDLLMP-GVGEIVGGSM 477
Query: 364 REDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWAT 423
R +D+L + K +DPK Y WYLD R YG+ PH G+GLG+ER + W+ +HIR
Sbjct: 478 RIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLGLERFICWLTNTNHIRDVC 537
Query: 424 LFPRTPARIYP 434
L+PR R P
Sbjct: 538 LYPRFVGRCVP 548
>pir||E82217 asparaginyl-tRNA synthetase VC1297 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655785|gb|AAF94456.1|
(AE004209) asparaginyl-tRNA synthetase [Vibrio cholerae]
Length = 481
Score = 240 bits (605), Expect = 3e-62
Identities = 162/469 (34%), Positives = 240/469 (50%), Gaps = 45/469 (9%)
Query: 1 MIEKTYCQDIKPELDGK-----RVKLAGWVYSNMRVGKKI-FLWIRDSTGI--IQTVIAK 52
+I TY + L GK V + GW+ + I FL I D + IQ V+
Sbjct: 13 VINMTYAP-VNDVLSGKLAVDSEVTVRGWIRTRRDSKAGISFLAIYDGSCFNPIQAVVPN 71
Query: 53 NVVGEDVFETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPI-PENPE 111
N+ D KL SV V G + + E+ +KV+ V + P
Sbjct: 72 NLNNYD--NEVLKLTTGCSVEVTGKIVESPASGQAFELAASDVKVVGWVEDADTYPMAKT 129
Query: 112 QASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGA 171
+ S E L + HL R+ + A+ RV+ L A + +G+ V P++ EG
Sbjct: 130 RHSIEYLREVAHLRPRTNVIGAVARVRNCLAQAIHRFYHEQGYFWVSAPLITASDAEGAG 189
Query: 172 TLFKLK--------------------YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFR 211
+F++ +F K +L+ S QL EA + KV++ P+FR
Sbjct: 190 EMFRVSTLDMENLPRTDAGKVDYNQDFFGKETFLTVSGQLNAEAYACAISKVYTFGPTFR 249
Query: 212 AEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTT 271
AE S T RHL EFW +E E A+ DL + K+ E+++ Y+ + L R+ ++E F D +
Sbjct: 250 AENSNTSRHLAEFWMVEPEVAFADLNTVAKLAEDMLKYVFKAVLAERRDDLEFFNDRINN 309
Query: 272 L------KNTEPPFPRISYDEAIEILQSKG----VKIEWGDDMGADEERVLTQE-FDRPF 320
+ E F ++ Y +AIEIL++ G +EWG D+ ++ ER L +E F P
Sbjct: 310 EVIARLEQFVESDFAQVDYTDAIEILKNCGKTFEFPVEWGIDLASEHERFLAEEHFKAPV 369
Query: 321 FVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGM 380
V YPK IKAFYM+ + D + V A D+LAP G GEIIGGS+RE+ D L R++E G+
Sbjct: 370 IVKNYPKDIKAFYMRMN-EDGKTVAAMDVLAP-GIGEIIGGSQREERLDILDARMREFGI 427
Query: 381 DPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTP 429
DP+ +WY DLR+YG+VPH+GFGLG ERLV++V + ++R FPRTP
Sbjct: 428 DPEHMDWYRDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTP 476
>sp|P17242|SYN_ECOLI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|68529|pir||SYECNT asparagine--tRNA ligase (EC
6.1.1.22) - Escherichia coli >gi|41000|emb|CAA48274.1|
(X68192) Asparaginyl-tRNA synthetase [Escherichia coli]
>gi|147935|gb|AAA24666.1| (M33145) asparaginyl-tRNA
synthetase (asnS) [Escherichia coli]
>gi|1651455|dbj|BAA35682.1| (D90731) Asparaginyl-tRNA
synthetase (EC 6.1.1.22) (asparagine-tRNA ligase)
(asnRS). [Escherichia coli] >gi|1787161|gb|AAC74016.1|
(AE000195) asparagine tRNA synthetase [Escherichia coli
K12]
Length = 466
Score = 236 bits (597), Expect = 3e-61
Identities = 159/446 (35%), Positives = 237/446 (52%), Gaps = 39/446 (8%)
Query: 19 VKLAGWVYSNMRVGKKI-FLWIRDSTGI--IQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
V + GWV + I FL + D + +Q VI ++ + E +L SVIV
Sbjct: 20 VTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYN--EDVLRLTTGCSVIVT 77
Query: 76 GIVKADERAPGGAEVHVEKLKVIQAVSE-FPIPENPEQASPELLLDYRHLHIRSPKVSAI 134
G V A E+ K++V V + P ++ S E L + HL R+ + A+
Sbjct: 78 GKVVASPGQGQQFEIQASKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAV 137
Query: 135 MRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK----------------- 177
RV+ TL A + +G+ V P++ EG +F++
Sbjct: 138 ARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDF 197
Query: 178 ---YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
+F K ++L+ S QL E L K+++ P+FRAE S T RHL EFW LE E A+
Sbjct: 198 DKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFA 257
Query: 235 DLWDIMKVEEELVSYMVQRTLELRKKEIEMF-----RDDLTTLKN-TEPPFPRISYDEAI 288
+L DI + E ++ Y+ + LE R +++ F +D ++ L+ E F ++ Y +A+
Sbjct: 258 NLNDIAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAV 317
Query: 289 EILQSKGVKIE----WGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDPRK 343
IL++ G K E WG D+ ++ ER L +E F P V YPK IKAFYM+ + D +
Sbjct: 318 TILENCGRKFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLN-EDGKT 376
Query: 344 VLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFG 403
V A D+LAP G GEIIGGS+RE+ D L +R+ E G++ +DY WY DLR+YG+VPHSGFG
Sbjct: 377 VAAMDVLAP-GIGEIIGGSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFG 435
Query: 404 LGVERLVAWVLKLDHIRWATLFPRTP 429
LG ERL+A+V + ++R FPRTP
Sbjct: 436 LGFERLIAYVTGVQNVRDVIPFPRTP 461
>pir||A82901 asparaginyl-tRNA synthetase UU365 [imported] - Ureaplasma
urealyticum >gi|6899346|gb|AAF30774.1|AE002133_7
(AE002133) asparaginyl-tRNA synthetase [Ureaplasma
urealyticum]
Length = 454
Score = 236 bits (596), Expect = 4e-61
Identities = 153/453 (33%), Positives = 251/453 (54%), Gaps = 27/453 (5%)
Query: 2 IEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKNVVGEDVF 60
I++ + QD +L+G+++++ WV SN R KKI FL + D + + V D +
Sbjct: 5 IKEIFNQDYV-KLEGQKIQIKAWVRSN-RDSKKIGFLVLNDGSSLTNLQAVYRVDKIDNY 62
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLD 120
E ++V++EG++K A E+ V ++++ E + N + L L+
Sbjct: 63 EEIAAARMWAAVVIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLNLETLRLN 122
Query: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD 180
HL R+ AIM+V+ TL A E++ + + + P+ EG F ++ FD
Sbjct: 123 -AHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSWLAAPLFTGNDAEGAGETFSIQKFD 181
Query: 181 ------KVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
K +LS + QL EA V++ P+FRAEKS T RHL EFW +E E A++
Sbjct: 182 NEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFWMIEPEMAFV 241
Query: 235 DLWDIMKVEEELVSYMVQRTLELRKKEIEMF--RDDLTTLKN----TEPPFPRISYDEAI 288
DL + + E+LV ++++ LE ++E+E R+D +K E F RI Y +A+
Sbjct: 242 DLKGMQDIVEDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAV 301
Query: 289 EIL--------QSKGVKIEWGDDMGADEERVLTQEFDR-PFFVYGYPKHIKAFYMKEDPN 339
+IL Q + +I +G D+G++ ER + + + + P F+ YPK IKAFYMK + +
Sbjct: 302 KILADAVKNGHQFENNEIFFGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLN-D 360
Query: 340 DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPH 399
D + V + D+L P G GE++GGS+RED+Y+KL++R +E M + +WYLDLR++G
Sbjct: 361 DQQTVASTDLLIP-GVGELVGGSQREDSYEKLLKRCQELKMPIESLQWYLDLRRFGYYMS 419
Query: 400 SGFGLGVERLVAWVLKLDHIRWATLFPRTPARI 432
SGFG+G ERLV +V +++I+ FPR+ +I
Sbjct: 420 SGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQI 452
>sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|3298338|dbj|BAA31457.1| (AB010464) aspartyl tRNA
synthetase [Haloferax volcanii]
Length = 433
Score = 235 bits (594), Expect = 6e-61
Identities = 150/440 (34%), Positives = 231/440 (52%), Gaps = 13/440 (2%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M +TY D +P G V +AGWV+ +G FL +RD++G IQ K+ + +D+
Sbjct: 1 MRNRTYTADAEP---GDTVTVAGWVHEVRDLGGIAFLILRDTSGKIQVKFEKDEMDDDLV 57
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVI-QAVSEFPI-PENPEQASPELL 118
ET + RES + V G V + RAP G EV E L VI +A ++ P+ P A
Sbjct: 58 ETGLGVHRESVISVTGEVDEEPRAPTGVEVTPESLDVIAEAEAQLPLDPSGKVDAELSTR 117
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
LD R L +R +V AI ++ + A R+ E+ P +V EGG LF + Y
Sbjct: 118 LDNRTLDLRKDEVKAIFEIRAEVQRAVRDKFRDLRATEINTPKIVATGTEGGTELFPITY 177
Query: 179 FDKVAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW 237
F + A+++QS QL+ + + GLE+V+ + P FRAE+ T RHL E ++ E+A++D
Sbjct: 178 FGQEAFMNQSPQLFKQLMVGSGLERVFEVGPIFRAEEHNTPRHLNEATSIDFESAFIDHT 237
Query: 238 DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGV- 296
+ M V E +V+ + E + E+E L P P Q G
Sbjct: 238 EAMDVCEAVVTAAYEAVEENCQDELEAL--GLEEEFERRPRVPAAHLRGGHRAHQRTGEL 295
Query: 297 --KIEWGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEG 354
++ WGDD+ + E+ L ++ +F+ +P IK FY+K+ +D DM+ P
Sbjct: 296 DEQLVWGDDLPTEGEKALGEDVGEHYFITDWPSEIKPFYIKDHDDDETLSTGFDMMHPNM 355
Query: 355 YGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVL 414
E++ G +RE +D LV +++G+DP +E+Y + KYG PH+GFGLG ERL+ +L
Sbjct: 356 --ELVSGGQREHRFDHLVAGFEQQGLDPDAFEYYTKMFKYGMPPHAGFGLGGERLIMTML 413
Query: 415 KLDHIRWATLFPRTPARIYP 434
L++IR A LFPR R+ P
Sbjct: 414 GLENIREAVLFPRDRQRLSP 433
>sp|O51128|SYN_BORBU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|7437580|pir||E70112 asparagine--tRNA ligase (EC
6.1.1.22) asnS - Lyme disease spirochete
>gi|2687998|gb|AAC66501.1| (AE001123) asparaginyl-tRNA
synthetase (asnS) [Borrelia burgdorferi]
Length = 466
Score = 235 bits (593), Expect = 8e-61
Identities = 156/458 (34%), Positives = 236/458 (51%), Gaps = 39/458 (8%)
Query: 10 IKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGI--IQTVIAKNVVGEDVF--ETAKK 65
+K + V + GW+ + GK F+ I D + + IQ VI + E+ F + KK
Sbjct: 13 LKNPILNSNVTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEE---ENQFSEKDLKK 69
Query: 66 LGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLH 125
L +S+ + G++ E+ VI P ++ S E L + HL
Sbjct: 70 LTTGTSISLTGLLVESPAKGQNYEIKTHSFNVIGETDPETYPLQKKRHSFEFLREIPHLR 129
Query: 126 IRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK-------- 177
IR+ AI RV+ + E+ + G+ + PI+ + EG +F++
Sbjct: 130 IRTNTFGAIARVRNKISYKIHEYFQKNGFFYINTPIITSNDGEGAGEMFRVSTLKFNKLN 189
Query: 178 -----------YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWH 226
+F K A+LS + QL+ EA L K+++ P+FRAE S T RH +EFW
Sbjct: 190 NALSNIDFKDDFFGKEAFLSVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHASEFWM 249
Query: 227 LELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTT-----LKNT-EPPFP 280
+E E A+ L D + + E+L+ Y++ L ++++ + + L+N F
Sbjct: 250 IEPEMAFYKLNDNIALAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVINSNFE 309
Query: 281 RISYDEAIEILQSKGVKIE----WGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMK 335
I+Y +AIEIL++ E WG D+ D ER LT+E F +P V YPK+ KAFYMK
Sbjct: 310 VITYTKAIEILENSKKNFEIKPYWGIDLQTDHERYLTEETFKKPVVVIDYPKNFKAFYMK 369
Query: 336 EDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYG 395
+ D + V D+L P+ GEIIGGSERED+ KL RIKE ++ + WYLDLR++G
Sbjct: 370 AN-KDNKTVKGMDILVPK-IGEIIGGSEREDDLQKLENRIKELNLNIEHLNWYLDLRRFG 427
Query: 396 SVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIY 433
S PHSGFGLG+ERLV + + +IR + FPRTP +Y
Sbjct: 428 SAPHSGFGLGLERLVQYSTGISNIRDSIPFPRTPKNLY 465
>emb|CAA10904.1| (AJ222644) asparaginyl-tRNA synthetase [Arabidopsis thaliana]
Length = 566
Score = 233 bits (589), Expect = 2e-60
Identities = 162/460 (35%), Positives = 238/460 (51%), Gaps = 50/460 (10%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGI--IQTVIAKNVVGEDVFETAKKLGRESSVI 73
G+ + + GWV + F+ I D + + +Q V+ + G D E+ L +SV
Sbjct: 108 GQSLNIMGWVRTLRSQSSVTFIEINDGSCLSNLQCVMTSDAEGYDQVESGSIL-TGASVS 166
Query: 74 VEGIVKADERAPGGAEVHVEKLKVI-QAVSEFPIPENPEQASPELLLDYRHLHIRSPKVS 132
V+G + A + E+ VEK+ V+ + S +PI + ++ S E L HL R+
Sbjct: 167 VQGTIVASQGTKQKVELKVEKIIVVGECDSSYPIQK--KRVSREFLRTKAHLRPRTNTFG 224
Query: 133 AIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF------------------ 174
A+ RV+ TL A ++ G+ V PI+ EG F
Sbjct: 225 AVARVRNTLAYATHKFFQESGFVWVASPIITASDCEGAGEQFCVTTLIPSSHEYTDTSID 284
Query: 175 ---KLK---------YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLT 222
K K +F K A+L+ S QL E L V++ P+FRAE S T RHL
Sbjct: 285 AIPKTKGGLIDWSQDFFGKPAFLTVSGQLNGETYATALSDVYTFGPTFRAENSNTSRHLA 344
Query: 223 EFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMF-----RDDLTTLKNT-E 276
EFW +E E A+ DL D M + Y+V+ L+ K+++E F + + L + E
Sbjct: 345 EFWMIEPELAFADLDDDMACATAYLQYVVKYVLDNCKEDMEFFDTWIEKGIIRRLSDVAE 404
Query: 277 PPFPRISYDEAIEILQSKGVK----IEWGDDMGADEERVLTQEF--DRPFFVYGYPKHIK 330
F ++ Y +AIEIL K ++WG D+ ++ ER +T+E RP + YPK IK
Sbjct: 405 KEFLQLGYTDAIEILLKANKKFDFPVKWGLDLQSEHERYITEEAFGGRPVIIRDYPKEIK 464
Query: 331 AFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLD 390
AFYM+E+ +D + V A DML P GE+IGGS+RE+ + L R+ E ++ + Y WYLD
Sbjct: 465 AFYMREN-DDGKTVAAMDMLVPR-IGELIGGSQREERLEVLEARLDELKLNKESYWWYLD 522
Query: 391 LRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPA 430
LR+YGSVPH+GFGLG ERLV +V +D+IR FPRTPA
Sbjct: 523 LRRYGSVPHAGFGLGFERLVQFVTGIDNIRDVIPFPRTPA 562
>sp|P52276|SYN_SYNY3 PROBABLE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE)
(ASNRS) >gi|7437579|pir||S75997 asparagine--tRNA ligase
(EC 6.1.1.22) - Synechocystis sp. (strain PCC 6803)
>gi|1001357|dbj|BAA10844.1| (D64006) asparaginyl-tRNA
synthetase [Synechocystis sp.]
Length = 513
Score = 233 bits (587), Expect = 4e-60
Identities = 150/442 (33%), Positives = 227/442 (50%), Gaps = 32/442 (7%)
Query: 18 RVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGI 77
+V + GW+ + + F+ + D + + + + D +L ++++VEG
Sbjct: 69 QVMVQGWLRTKRTLKDFSFVEVNDGSSLANLQVVLDGSLADYDRLLSQLQTGAALVVEGK 128
Query: 78 VKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSAIMRV 137
+ E+ KL+++ P ++ S E L HL R+ + A+MRV
Sbjct: 129 LAPSPGKGQRVELKATKLELLGGADPGSYPLQKKRHSFEFLRTIGHLRPRTNTIGAVMRV 188
Query: 138 KETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK-------------------Y 178
+ A ++ G+ V PI+ EG LFK+ +
Sbjct: 189 RNACATAIHQFFQERGFLWVHTPIITASDCEGAGDLFKVTTLDLQRVPKNGEGIDYSQDF 248
Query: 179 FDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWD 238
F K AYL+ S QL E + V++ P+FRAE S T RHL EFW +E E A+ DL
Sbjct: 249 FGKQAYLTVSGQLEAEVMALAFQNVYTFGPTFRAENSNTSRHLAEFWMVEPEMAFCDLEG 308
Query: 239 IMKVEEELVSYMVQRTLELRKKEIEMF--RDDLTTLKNTEP----PFPRISYDEAIEILQ 292
+ EE + Y+ + LE +++E F R D T L + F ++Y EAI++L+
Sbjct: 309 DRQWAEEFLKYIFKFVLEKCPEDMEFFDQRIDNTVLATADNIINNEFAWLTYSEAIKLLE 368
Query: 293 SKGVKIE----WGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAA 347
K E WG D+ ++ ER L + F RP V YPK IKAFYM+ + +D + V A
Sbjct: 369 KADQKFEYPVAWGVDLQSEHERYLAETVFKRPTIVTDYPKDIKAFYMRLN-DDGKTVAAM 427
Query: 348 DMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVE 407
D+LAP+ GEIIGGS+RE+ D L QR++E+G+ +D WYLDLR+YGSVPH+GFGLG E
Sbjct: 428 DILAPK-IGEIIGGSQREERLDILTQRMQEQGVPEEDLWWYLDLRRYGSVPHAGFGLGFE 486
Query: 408 RLVAWVLKLDHIRWATLFPRTP 429
R+V ++ + +IR FPRTP
Sbjct: 487 RIVQFMTGMANIRDVIPFPRTP 508
>sp|P47359|SYN_MYCGE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1361447|pir||E64212 asparagine--tRNA ligase (EC
6.1.1.22) - Mycoplasma genitalium
>gi|3844702|gb|AAC71331.1| (U39691) asparaginyl-tRNA
synthetase (asnS) [Mycoplasma genitalium]
Length = 456
Score = 232 bits (585), Expect = 7e-60
Identities = 148/445 (33%), Positives = 245/445 (54%), Gaps = 30/445 (6%)
Query: 13 ELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGI--IQTVIAKNVVGEDVFETAKKLGRES 70
+ + K++KL+GWV + IFL I D + I +Q V+ K VF + + S
Sbjct: 15 KFNNKQIKLSGWVKNKRASANIIFLAISDGSSINTLQAVV-KQEDNPQVFSLLQTVNLAS 73
Query: 71 SVIVEGIVKADERAPGGAEVHVEKLKVI-QAVSEFPIPENPEQASPELLLDYRHLHIRSP 129
+V+V G + +A E+ ++++ ++ QA S++P+ + ++ S E HL +R+
Sbjct: 74 AVMVWGEIILTPKAKQPLELKLKQVSLLAQAESDYPLQK--KEHSQEFFRSNAHLRVRAK 131
Query: 130 KVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK----YFDKVAYL 185
A+M+++ L A E+ + + V PIL + EG F +K +F+K +L
Sbjct: 132 TYFAVMKIRSVLSHAIFEYFFKNDFILVQSPILTSNDCEGAGETFVIKDSETFFNKTTFL 191
Query: 186 SQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEE 245
+ S Q EA +KV++ P+FRAEKS T RHL+EFW +E E A+ +L D+M++ +
Sbjct: 192 TVSGQFGAEAFAQAFKKVFTFGPTFRAEKSHTNRHLSEFWMIEPEIAFANLKDLMQLIQN 251
Query: 246 LVSYMVQRTLELRKKEIEMF-----RDDLTTLKN--TEPPFPRISYDEAIEILQ----SK 294
L+ +++++ +E E+ + D ++ LK + FP I Y +A+ IL+ +K
Sbjct: 252 LIKFLIKKVMENASDELNVLAKQFSNDIISNLKTIISTKKFPIIEYSKALAILKESSDTK 311
Query: 295 GVKIEWGD-----DMGADEERVLTQEF--DRPFFVYGYPKHIKAFYMKEDPNDPRKVLAA 347
E D D+ + ER L +++ ++P FV YPK +KAFYMK + D + V A
Sbjct: 312 KTNFELNDFSFGIDLKTEHERFLCEQYFQNQPLFVINYPKELKAFYMKTN-TDNKTVAAV 370
Query: 348 DMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVE 407
D+L P+ GEI GGSERE + ++L R + +D K WYLD+RK+G +GFGLG +
Sbjct: 371 DLLLPK-IGEICGGSERESDLNQLKNRCQSLNIDTKSLNWYLDMRKWGYFASAGFGLGFD 429
Query: 408 RLVAWVLKLDHIRWATLFPRTPARI 432
RL+A++ L++IR A FPR I
Sbjct: 430 RLLAYICGLENIRDAIPFPRVHGTI 454
>sp|P75521|SYN_MYCPN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|2146064|pir||S73906 asparagine--tRNA ligase (EC
6.1.1.22) asnS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1674281|gb|AAB96228.1| (AE000057)
asparaginyl-tRNA synthetase [Mycoplasma pneumoniae]
Length = 455
Score = 226 bits (570), Expect = 4e-58
Identities = 144/447 (32%), Positives = 239/447 (53%), Gaps = 35/447 (7%)
Query: 13 ELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSV 72
+ K++KL GW+ + IFL + D + ++ ++F A+ + S+V
Sbjct: 15 QFKNKKIKLTGWLKNKRTSANIIFLEVNDGSTLLNLQAVVKQDQPELFALAESISLASAV 74
Query: 73 IVEGIVKADERAPGGAEVHVEKLKVIQ-AVSEFPIPENPEQASPELLLDYRHLHIRSPKV 131
V G V ++ E+ V+++ V+ A +++P+ + ++ S E + +L +R+
Sbjct: 75 SVSGTVALTPKSKQPLELVVKQINVLSTARADYPLQK--KEHSLEFFRNNAYLRVRARTY 132
Query: 132 SAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK----YFDKVAYLSQ 187
AIM+V+ L A ++ + + V PIL + EG F+LK +F+K YL+
Sbjct: 133 FAIMKVRSLLSQAIFDYFFKNDFVLVHSPILTSNDCEGAGETFELKQGKEFFNKTTYLTV 192
Query: 188 SAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELV 247
S Q E +KV++ P+FRAEKS T RHL+EFW +E E A+ +L D++K+ E V
Sbjct: 193 SGQFGAECYAQAFKKVFTFGPTFRAEKSHTSRHLSEFWMIEPEVAFANLKDLIKLIESTV 252
Query: 248 SYMVQRTLELRKKEIEMFRDD-----------LTTLKNTEPPFPRISYDEAIEILQSKGV 296
++++ ++ K+E++ +T+ KN F + Y +A+EIL++
Sbjct: 253 KTVIKQVMQKAKQELDFLEKQFDVKLMERLKQITSTKN----FHVLEYTKALEILKTAQA 308
Query: 297 K---------IEWGDDMGADEERVLTQEF--DRPFFVYGYPKHIKAFYMKEDPNDPRKVL 345
+G D+ + ER L ++ ++P FV YPK KAFYMK++ D R V
Sbjct: 309 SGQANFEVQDFNFGLDLKTEHERFLCEQHFHNQPVFVINYPKDFKAFYMKQNA-DGRTVG 367
Query: 346 AADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLG 405
A D+L P+ GEI GGSERE N +KLV+R + +D + WYLD+RK+G +GFGLG
Sbjct: 368 AVDLLFPQ-IGEICGGSEREGNLEKLVERCQAMQIDTQTLNWYLDMRKWGYFASAGFGLG 426
Query: 406 VERLVAWVLKLDHIRWATLFPRTPARI 432
+RL+A++ L++IR A FPR I
Sbjct: 427 FDRLLAYICGLENIRDAIPFPRAHGSI 453
>gb|AAF61689.1| (AF219996) aspartyl-tRNA synthetase 2 [Thermus thermophilus]
Length = 422
Score = 222 bits (561), Expect = 5e-57
Identities = 141/436 (32%), Positives = 241/436 (54%), Gaps = 28/436 (6%)
Query: 8 QDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLG 67
+D+K + G+ V+L G+++ +G+ FL +RD +G++Q V K
Sbjct: 6 RDLKAHV-GQEVELLGFLHWRRDLGRIQFLLLRDRSGVVQVVTGG----------LKLPL 54
Query: 68 RESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSE---FPIPENPEQASPELLLDYRHL 124
ES++ V G+V + +APGG EV ++++V+ E IP+ +A+P+ LL+YR++
Sbjct: 55 PESALRVRGLVVENAKAPGGLEVQAKEVEVLSPALEPTPVEIPKEEWRANPDTLLEYRYV 114
Query: 125 HIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAY 184
+R K A ++V+ L+ R +L R+ + E+F P +V EGG+ LF + YF+K AY
Sbjct: 115 TLRGEKARAPLKVQAALVRGFRRYLDRQDFTEIFTPKVVRAGAEGGSGLFGVDYFEKRAY 174
Query: 185 LSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM-DLWDIMKVE 243
L+QS QLY + + E+V+ + P +R E+ T RHL E+ L++E ++ D D+M++E
Sbjct: 175 LAQSPQLYKQIMVGVFERVYEVAPVWRMEEHHTSRHLNEYLSLDVEMGFIADEEDLMRLE 234
Query: 244 EELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWGDD 303
E L++ M++ L EI + T + PR+++ EA IL+ + + G D
Sbjct: 235 EALLAEMLEEALNTAGDEIRLLG---ATWPSFPQDIPRLTHAEAKRILKEE-LGYPVGQD 290
Query: 304 MGADEERVLTQEFDRPF-----FVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEI 358
+ + ER+L + + FV YP+ ++ FY P + + D+L G EI
Sbjct: 291 LSEEAERLLGEYAKERWGSDWLFVTRYPRSVRPFYTY--PEEDGTTRSFDLLF-RGL-EI 346
Query: 359 IGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDH 418
G +R Y++L++ +K +GMDP+ + YL++ KYG PH GF +G ERL +L L +
Sbjct: 347 TSGGQRIHRYEELLESLKAKGMDPEAFHGYLEVFKYGMPPHGGFAIGAERLTQKLLGLPN 406
Query: 419 IRWATLFPRTPARIYP 434
+R+A FPR R+ P
Sbjct: 407 VRYARAFPRDRHRLTP 422
>pir||H75443 aspartyl-tRNA synthetase, non-discriminating - Deinococcus
radiodurans (strain R1)
>gi|6458780|gb|AAF10623.1|AE001956_4 (AE001956)
aspartyl-tRNA synthetase, non-discriminating
[Deinococcus radiodurans]
Length = 435
Score = 217 bits (548), Expect = 2e-55
Identities = 149/446 (33%), Positives = 235/446 (52%), Gaps = 28/446 (6%)
Query: 2 IEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFE 61
+++T +++ P+ +G+ VKL G+V++ +G FL +RD TG+ Q V + +
Sbjct: 5 LKRTLTREL-PQHEGQTVKLQGFVHARRDLGGVQFLVLRDVTGVTQCVGSGLTLPL---- 59
Query: 62 TAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSE---FPIPENPEQASPELL 118
ESSV V G VKA +APGG EV VE +VI A +E IP+ +PE +
Sbjct: 60 ------AESSVEVVGKVKAHPKAPGGFEVQVEDFRVISAATEATPVEIPKMEWNVNPETM 113
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
LDYR + +R K A ++V+ L+ A R L EG+ E+ P +V+ EGGA LF + Y
Sbjct: 114 LDYRVVTVRGLKERAALKVQAELVDAFRAHLRGEGFTEISTPKIVSAGAEGGANLFPIDY 173
Query: 179 FDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM-DLW 237
F AYL+QS QLY + + E+V+ + +RAE+ T RHL E+ L++E ++ D
Sbjct: 174 FGHPAYLAQSPQLYKQIMVGVFERVFEVAAVYRAEEHATSRHLNEYLSLDVEMGFIEDEE 233
Query: 238 DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVK 297
D+M +E L++ +++R + E E+ T+ + PRI+ +A +++ K
Sbjct: 234 DVMGLENRLLASIMERLRATSQAEFELLG---ATIPDVPAHIPRITLMDARQLVTEKYGH 290
Query: 298 IEWGDDMGADEERVLTQEFDRP-----FFVYGYPKHIKAFY----MKEDPNDPRKVLAAD 348
G D+ + ER+L+Q F FV YP+ + FY + ED + +V
Sbjct: 291 PVGGKDLDPEAERLLSQHFAETEGSDFVFVTKYPRAARPFYAHPELNEDGSVNGEVTRGF 350
Query: 349 MLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVER 408
L G EI G +R +Y L+ I + P+ E Y ++ KYG PH GF +G ER
Sbjct: 351 DLLFRGI-EITSGGQRIHDYGMLMDSIAAYKLKPESLEGYTEVFKYGMPPHGGFAIGAER 409
Query: 409 LVAWVLKLDHIRWATLFPRTPARIYP 434
L A +L + ++R+A FPR R+ P
Sbjct: 410 LTAKLLGIANVRYARAFPRDRHRLTP 435
>sp|O83618|SYN_TREPA ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|7437574|pir||F71302 asparagine--tRNA ligase (EC
6.1.1.22) (asnS) - syphilis spirochete
>gi|3322907|gb|AAC65585.1| (AE001236) asparaginyl-tRNA
synthetase (asnS) [Treponema pallidum]
Length = 523
Score = 215 bits (541), Expect = 1e-54
Identities = 144/439 (32%), Positives = 208/439 (46%), Gaps = 67/439 (15%)
Query: 56 GEDVFETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP 115
GE + +T K++ + + EG + A E+ L V+ P + S
Sbjct: 82 GETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEAPAETYPLQKKSHSF 141
Query: 116 ELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFK 175
E L + HL R+ +A RV+ L A + + V PI+ EG LF+
Sbjct: 142 EFLRAHAHLRARTSTFAACARVRSALAGAVHRFFSERHFQYVHTPIITASDCEGAGELFR 201
Query: 176 LKYFD----------------------------KVAYLSQSAQLYLEAAIFGLEKVWSLT 207
+ FD K A L+ S QL EA L ++++
Sbjct: 202 VTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLTVSGQLQGEAYALALTRIYTFG 261
Query: 208 PSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRD 267
P+FRAE S T RHL+EFW +E E A+ + D M V EE ++Y+++ L+ ++I +
Sbjct: 262 PTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEFLAYLLRAALKDCAQDIAFLDE 321
Query: 268 DLT---------------TLKNTEP-----------------PFPRISYDEAIEILQSKG 295
+ T P P R++Y EAI++L++ G
Sbjct: 322 RAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRLTYTEAIKLLENSG 381
Query: 296 VKIE----WGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADML 350
E WG D+ ++ E LT+E F P VY YPK IKAFYMK + D V + D+L
Sbjct: 382 RSFEFPVRWGCDLQSEHECFLTEEVFHGPVIVYDYPKEIKAFYMKLNA-DGTTVRSMDLL 440
Query: 351 APEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLV 410
P G GEI+GGSERE+ ++ L RI+ G DP DY WY DLR++G+ PH+GFGLG ERL+
Sbjct: 441 VP-GLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDLRRFGTAPHAGFGLGFERLL 499
Query: 411 AWVLKLDHIRWATLFPRTP 429
+V L +IR FPRTP
Sbjct: 500 QYVTGLGNIRDVIPFPRTP 518
>emb|CAB91185.1| (AL355921) asparaginyl-trna synthetase, mitochondrial
[Schizosaccharomyces pombe]
Length = 441
Score = 208 bits (525), Expect = 8e-53
Identities = 144/448 (32%), Positives = 231/448 (51%), Gaps = 55/448 (12%)
Query: 15 DGKRVKLAGWVYSNMRVGKKIFLWIRDST--GIIQTVIAKNVVGEDVFETAKKLGRESSV 72
+G+ + + GWV S ++ F + D T +Q V + E +KKL +SV
Sbjct: 19 NGELISINGWVRSIRKLKNVCFAMVSDGTCQQALQVVTSP--------EQSKKLSYGASV 70
Query: 73 IVEGIVKADERAPGGA---EVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSP 129
+EG + + A G E+ EK+K+ +++ P + + E+L HL +R+
Sbjct: 71 NIEGQLAVSKNAKLGLQQYELLAEKIKIYGQINDDNYPIQKKHLTTEMLRQIPHLRLRTA 130
Query: 130 KVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK------------ 177
K I R++ + A R++ + + E PPI+ + EG +F L
Sbjct: 131 KQGEIFRLRSDSLKALRQFFSSKDFTETNPPIITSSDCEGAGEVFTLTPQETHKNKSFER 190
Query: 178 -----YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAA 232
+FD+ A+L+ S QL+LEA GL +V++++P+FRAE+S T RHL EFW LE E A
Sbjct: 191 DDQKHFFDRPAFLTVSTQLHLEALALGLSRVYTISPAFRAEQSHTSRHLAEFWMLEAEVA 250
Query: 233 WM-DLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEIL 291
+M L + + E+++ Y + +E RD L P+ ++Y EAIE L
Sbjct: 251 FMTSLSQLTSLMEDMIKYTLNSLMEQ-----NYHRDHWDQLLK---PWKCMTYSEAIEEL 302
Query: 292 QS--KGVKI--EWGDDMGADEERVLTQEFDR-PFFVYGYPKHIKAFYMKEDPNDPRKVLA 346
+ K K +WG+D+ ++ E+ L + + P FV YP+ IK FYMK + P V A
Sbjct: 303 SAVKKTWKYPPKWGNDLSSEHEKYLCEILHKTPVFVTDYPQKIKPFYMKS--SGPDTVAA 360
Query: 347 ADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGV 406
D+L P+ GE+ GGS R+D+ D E P + +WYLDL KY + PH GFGLG+
Sbjct: 361 VDLLVPQ-VGELAGGSLRKDHLD-------EYKTYPPELQWYLDLMKYSNAPHGGFGLGI 412
Query: 407 ERLVAWVL-KLDHIRWATLFPRTPARIY 433
ERL+A++ + +++ FPR+ I+
Sbjct: 413 ERLIAFLEGENTNVKETIPFPRSVGSIF 440
>gb|AAD46681.1|AF170909_1 (AF170909) SYNC1 protein [Arabidopsis thaliana]
>gi|10176772|dbj|BAB09886.1| (AB013392) SYNC1 protein
[Arabidopsis thaliana]
Length = 572
Score = 206 bits (520), Expect = 3e-52
Identities = 117/270 (43%), Positives = 163/270 (60%), Gaps = 20/270 (7%)
Query: 178 YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW 237
+F + A+L+ S QL +E L V++ P+FRAE S T RHL EFW +E E A+ DL
Sbjct: 304 FFGRQAFLTVSGQLQVETYACALSNVYTFGPTFRAENSHTSRHLAEFWMVEPEIAFADLE 363
Query: 238 DIMKVEEELVSYMVQRTLELRKKEIEMFR--------DDLTTLKNTEPPFPRISYDEAIE 289
D M E V YM LE ++E+ D L + +T PF RI+Y +AIE
Sbjct: 364 DDMNCAEAYVKYMCNWLLEKCYADMELMAKNFDSGCIDRLKLVAST--PFGRITYTKAIE 421
Query: 290 ILQSKGVK-------IEWGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDP 341
+L+ K +EWG D+ ++ ER LT+ F +P VY YPK IKAFYM+ + +D
Sbjct: 422 LLEEAVAKGKEFDNNVEWGIDLASEHERYLTEVLFQKPLIVYNYPKGIKAFYMRLN-DDE 480
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSG 401
+ V A D+L P+ GE+IGGS+RE+ YD + +RI+E G+ + YEWYLDLR+YG+V H G
Sbjct: 481 KTVAAMDVLVPK-VGELIGGSQREERYDVIKKRIEEMGLPIEPYEWYLDLRRYGTVKHCG 539
Query: 402 FGLGVERLVAWVLKLDHIRWATLFPRTPAR 431
FGLG ER++ + LD+IR FPR P +
Sbjct: 540 FGLGFERMILFATGLDNIRDVIPFPRYPGK 569
>pir||H71612 asparagine--tRNA ligase (EC 6.1.1.22) (OO, TP) PFB0525w - malaria
parasite (Plasmodium falciparum)
>gi|3845207|gb|AAC71894.1| (AE001400) asparaginyl-tRNA
synthetase (OO, TP) [Plasmodium falciparum]
Length = 610
Score = 205 bits (516), Expect = 9e-52
Identities = 115/267 (43%), Positives = 164/267 (61%), Gaps = 13/267 (4%)
Query: 174 FKLKYFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAW 233
+K +F K A+L+ S QL LE + V++ P+FRAE S T RHL EFW +E E A+
Sbjct: 341 YKKDFFSKQAFLTVSGQLSLENLCSSMGDVYTFGPTFRAENSHTSRHLAEFWMIEPEIAF 400
Query: 234 MDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTT-----LKNT-EPPFPRISYDEA 287
DL+D M++ E + Y + L +I F +++ T LKN F +I+Y A
Sbjct: 401 ADLYDNMELAEAYIKYCIDYVLNNNFHDIYYFEENVETNLIKRLKNILNEDFAKITYTNA 460
Query: 288 IEILQSKG----VKIEWGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDPR 342
IEILQ+ VK+EWG D+ ++ ER + ++ F +P VY YPK +KAFYMK + D +
Sbjct: 461 IEILQNYSDSFEVKVEWGMDLQSEHERFIAEKIFKKPVIVYNYPKDLKAFYMKLN-EDNK 519
Query: 343 KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGF 402
V A D+L P+ GE+IGGS+REDN ++L + IKE+ ++ Y WY LR+YGS PH+GF
Sbjct: 520 TVAAMDVLVPK-IGEVIGGSQREDNLERLDKMIKEKKLNIDSYWWYRQLRQYGSHPHAGF 578
Query: 403 GLGVERLVAWVLKLDHIRWATLFPRTP 429
GLG ERL+ V +D+I+ FPR P
Sbjct: 579 GLGFERLIMLVTGVDNIKDTIPFPRYP 605
>sp|P57441|SYN_BUCAI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|10039030|dbj|BAB13064.1| (AP001119) asparaginyl-tRNA
synthetase [Buchnera sp. APS]
Length = 466
Score = 205 bits (516), Expect = 9e-52
Identities = 148/453 (32%), Positives = 230/453 (50%), Gaps = 45/453 (9%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQT---VIAKNVVGEDVFETAKKLGRESSVIVE 75
+ + GWV N R K F +I G VIA N + + ++ L SV++
Sbjct: 20 ITVCGWV-RNRRSSKSGFSFITIYDGSCFNSIQVIANNTL-PNYYKEILHLTTGCSVMLS 77
Query: 76 GIVKADERAPGGAEVHVEKLKVIQAVSE---FPIPENPEQASPELLLDYRHLHIRSPKVS 132
G + E+ ++K+KV+ V +PI + ++ S E L + HL R+ +
Sbjct: 78 GKLILSIGDKQKYEIQLKKIKVLGWVENPETYPI--SSKKHSTEYLREVAHLRSRTNLIG 135
Query: 133 AIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK--------------- 177
AI R++ ++ + + +E ++ V PI+ + EG +F++
Sbjct: 136 AIARIRNYILHSLHHFFYKEKYYWVPTPIITSLNTEGAGEMFRVSTLDMENIPKNLDSSV 195
Query: 178 -----YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAA 232
+F K ++L+ S QL LE L KV++ P+FRAE S T RHL EFW LE+E+A
Sbjct: 196 DFKKDFFGKESFLTVSGQLNLETYACSLSKVYTFGPTFRAENSNTGRHLAEFWMLEVESA 255
Query: 233 WMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEP-------PFPRISYD 285
+ DL DI E ++ Y+ + L+ +I F ++ T + F RI Y
Sbjct: 256 FTDLNDISDFAECMLKYVCKSLLKKCITDIN-FLENYTNSNIVDRLEKFLLVDFVRIDYV 314
Query: 286 EAIEILQSKGVKIE----WGDDMGADEERVLTQEFDR-PFFVYGYPKHIKAFYMKEDPND 340
E I IL +K G D+ ++ ER L + + + P V YPK +KAFYM+ + ND
Sbjct: 315 EVINILLDSKIKFNNSVFLGIDLSSEHERFLVENYFKIPVIVKNYPKELKAFYMRLN-ND 373
Query: 341 PRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHS 400
+ V A D+L P GE+IGGS+RE+ L +R+ E G+ +DY WY DLR+YG+VPHS
Sbjct: 374 KKTVAAIDILVPN-VGELIGGSQREERIAILDERLLELGLKKEDYWWYRDLRRYGTVPHS 432
Query: 401 GFGLGVERLVAWVLKLDHIRWATLFPRTPARIY 433
GFG+G ERL+++ + +IR FPRT Y
Sbjct: 433 GFGMGFERLISYFTGITNIRDLIPFPRTVNNAY 465
>gb|AAD55509.1|AC008148_19 (AC008148) Similar to asparaginyl-tRNA synthetases [Arabidopsis
thaliana]
Length = 571
Score = 203 bits (510), Expect = 4e-51
Identities = 116/270 (42%), Positives = 166/270 (60%), Gaps = 18/270 (6%)
Query: 178 YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW 237
+F + A+L+ S QL +E L V++ P+FRAE S T RHL EFW +E E A+ D+
Sbjct: 301 FFGRQAFLTVSGQLQVETYACALSSVYTFGPTFRAENSHTSRHLAEFWMVEPEIAFADIH 360
Query: 238 DIMKVEEELVSYMVQRTLELRKKEIEMFRDDL----TTLKN--TEPPFPRISYDEAIE-- 289
D M E V YM + ++ ++E+ ++ T N + F R++Y EAIE
Sbjct: 361 DDMNCAEAYVKYMCKWLMDKCGDDMELMDKNVDEGCTKRLNMVAKASFKRVTYTEAIERL 420
Query: 290 ---ILQSKGV---KIEWGDDMGADEERVLTQ-EFD-RPFFVYGYPKHIKAFYMKEDPNDP 341
+ Q K V K+EWG D+ ++ ER LT+ EFD +P VY YPK IKAFYM+ + +D
Sbjct: 421 EKAVAQGKVVFDNKVEWGIDLASEHERYLTEVEFDQKPIIVYNYPKGIKAFYMRLN-DDE 479
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSG 401
+ V A D+L P+ GE+IGGS+RE+ YD + QRI+E G+ + YEWYLDLR+YG+V H G
Sbjct: 480 KTVAAMDVLVPK-VGELIGGSQREERYDVIKQRIEEMGLPMEPYEWYLDLRRYGTVKHCG 538
Query: 402 FGLGVERLVAWVLKLDHIRWATLFPRTPAR 431
FGLG ER++ + +D+IR FPR P +
Sbjct: 539 FGLGFERMIQFATGIDNIRDVIPFPRYPGK 568
>gi|4557513 aspartyl-tRNA synthetase [Homo sapiens]
>gi|135098|sp|P14868|SYD_HUMAN ASPARTYL-TRNA SYNTHETASE
(ASPARTATE--TRNA LIGASE) (ASPRS) >gi|68530|pir||SYHUDT
aspartate--tRNA ligase (EC 6.1.1.12) [similarity] -
human >gi|179102|gb|AAA35567.1| (J05032) aspartyl-tRNA
synthetase [Homo sapiens]
Length = 500
Score = 196 bits (492), Expect = 6e-49
Identities = 139/444 (31%), Positives = 232/444 (51%), Gaps = 42/444 (9%)
Query: 25 VYSNMRVGKKIFLWIRDSTGIIQTVIAK-NVVGEDVFETAKKLGRESSVIVEGIVKADER 83
V+++ GK+ FL +R +Q ++A + + + + A + +ES V VEG+V+ +
Sbjct: 65 VHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVVRKVNQ 124
Query: 84 APGGA-----EVHVEKLKVIQ-AVSEFPIPEN----PEQASPE---------LLLDYRHL 124
G E+HV+K+ VI A P+ + PEQ E LD R +
Sbjct: 125 KIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEQEGEEEGRATVNQDTRLDNRVI 184
Query: 125 HIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAY 184
+R+ A+ R++ + RE L+ +G+ E+ P +++ A EGGA +F + YF AY
Sbjct: 185 DLRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAY 244
Query: 185 LSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVE 243
L+QS QLY + I EKV+S+ P FRAE S T RHLTEF L++E A+ + +V
Sbjct: 245 LAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFN--YHYHEVM 302
Query: 244 EELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEP--------PFPRISYDEAIEILQSKG 295
EE+ MVQ L+ E F+ ++ T+ P P R+ Y EA+ +L+ G
Sbjct: 303 EEIADTMVQIFKGLQ----ERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAG 358
Query: 296 VKIEWGDDMGADEERVL----TQEFDRPFFVYG-YPKHIKAFYMKEDPNDPRKVLAADML 350
V++ DD+ E++L +++D F++ YP ++ FY DP +P++ + DM
Sbjct: 359 VEMGDEDDLSTPNEKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSKSYDMF 418
Query: 351 APEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLV 410
EI+ G++R + L +R G D + + Y+D ++G+ PH+G G+G+ER+
Sbjct: 419 MRGE--EILSGAQRIHDPQLLTERALHHGNDLEKIKAYIDSFRFGAPPHAGGGIGLERVT 476
Query: 411 AWVLKLDHIRWATLFPRTPARIYP 434
L L ++R ++FPR P R+ P
Sbjct: 477 MLFLGLHNVRQTSMFPRDPKRLTP 500
>gi|11429379 aspartyl-tRNA synthetase [Homo sapiens]
Length = 484
Score = 194 bits (488), Expect = 2e-48
Identities = 136/444 (30%), Positives = 230/444 (51%), Gaps = 42/444 (9%)
Query: 25 VYSNMRVGKKIFLWIRDSTGIIQTVIAK-NVVGEDVFETAKKLGRESSVIVEGIVKADER 83
V+++ GK+ FL +R +Q ++A + + + + A + +ES V VEG+V+ +
Sbjct: 49 VHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVVRKVNQ 108
Query: 84 APGGA-----EVHVEKLKVIQ-AVSEFPIP-------------ENPEQASPELLLDYRHL 124
G E+HV+K+ VI A P+ E + + LD R +
Sbjct: 109 KIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVI 168
Query: 125 HIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAY 184
+R+ A+ R++ + RE L+ +G+ E+ P +++ A EGGA +F + YF AY
Sbjct: 169 DLRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAY 228
Query: 185 LSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVE 243
L+QS QLY + I EKV+S+ P FRAE S T RHLTEF L++E A+ + +V
Sbjct: 229 LAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFN--YHYHEVM 286
Query: 244 EELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEP--------PFPRISYDEAIEILQSKG 295
EE+ MVQ L+ E F+ ++ T+ P P R+ Y EA+ +L+ G
Sbjct: 287 EEIADTMVQIFKGLQ----ERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAG 342
Query: 296 VKIEWGDDMGADEERVL----TQEFDRPFFVYG-YPKHIKAFYMKEDPNDPRKVLAADML 350
V++ DD+ E++L +++D F++ YP ++ FY DP +P++ + DM
Sbjct: 343 VEMGDEDDLSTPNEKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMF 402
Query: 351 APEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLV 410
EI+ G++R + L +R G D + + Y+D ++G+ PH+G G+G+ER+
Sbjct: 403 MRGE--EILSGAQRIHDPQLLTERALHHGTDLEKIKAYIDSFRFGAPPHAGGGIGLERVT 460
Query: 411 AWVLKLDHIRWATLFPRTPARIYP 434
L L ++R ++FPR P R+ P
Sbjct: 461 MLFLGLHNVRQTSMFPRDPKRLTP 484
>pir||T40867 aspartate--tRNA ligase (EC 6.1.1.12) [similarity] - fission yeast
(Schizosaccharomyces pombe) >gi|3618213|emb|CAA20876.1|
(AL031579) aspartyl-trna synthetase, cytoplasmic
[Schizosaccharomyces pombe]
Length = 580
Score = 192 bits (483), Expect = 6e-48
Identities = 151/493 (30%), Positives = 240/493 (48%), Gaps = 64/493 (12%)
Query: 4 KTYCQ--DIKPELDGKRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQT--VIAKNVVGED 58
+TY Q DI + DG+ V L VY++ G K+ F +R IQ V+ K+ + +
Sbjct: 90 RTYTQISDISAKNDGQTVLLRARVYTSRLQGNKMCFFSLRQKYDTIQALAVVNKDTISKQ 149
Query: 59 VFETAKKLGRESSVIVEGIVKADER-----APGGAEVHVEKLKVIQAV------------ 101
+ + + ES V+VEGIVK AE+H+ + VI +
Sbjct: 150 MVKWCGSISLESIVLVEGIVKKSPEIIKSATVQDAEIHISSIYVISPIKKNLPFLVEDAG 209
Query: 102 -SEFPIPENPEQASP----------ELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLL 150
SE I E+ E A+ + LD R L +R+P AI ++ + A RE+LL
Sbjct: 210 RSEEQIRESEENAAEGDSKFVRVNLDTRLDNRVLDLRTPTNQAIFDIQAGICQAFREFLL 269
Query: 151 REGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPS 209
++E+ P + + EGG+ +FK++YF +LSQS QLY + I E+V+ + P
Sbjct: 270 SNSFNEIHTPKMSGASSEGGSNVFKIQYFKTDGFLSQSPQLYKQMLIAADRERVFEIGPV 329
Query: 210 FRAEKSRTRRHLTEFWHLELEAAWMDLW-DIMKVEEELVSYMVQRTLELRKKEIEMFRDD 268
FRAE S T RH+TEF L+LE A+ + + ++M+ E+L Y+ + E K++ + R
Sbjct: 330 FRAEDSNTYRHMTEFTGLDLEMAFNEHYHEVMEFIEKLFLYIFKTIREKYAKQVAVVRQQ 389
Query: 269 LTTLKNTEPPFPRI--SYDEAIEILQSKGVKIEW-------------------GDDMGAD 307
+ P RI + +A+++L+ G + + DD
Sbjct: 390 YPSEDFILPDADRIRFHFKDAVKLLKEAGYRKQLVPGQKVPEDEEFHYCEDPEFDDFSTP 449
Query: 308 EERVLTQ----EFDRPFFVYG-YPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGS 362
EER L Q ++ F+V YP ++ FY DP DPR + D EI+ G+
Sbjct: 450 EERALGQIVREKYHTDFYVIDKYPSSVRPFYTMPDPEDPRYSNSYDFFMKG--QEIMSGA 507
Query: 363 EREDNYDKLVQRIKEEGMDPK-DYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRW 421
+R + + LV+R+K G+ P + Y+D G PH+G G+G+ER+V + L L +IR
Sbjct: 508 QRIHDPELLVERMKALGVSPDVGLQQYIDAFAIGCPPHAGGGIGLERVVMFYLNLPNIRL 567
Query: 422 ATLFPRTPARIYP 434
A+ FPR P R+ P
Sbjct: 568 ASSFPRDPKRLLP 580
>pir||T04810 aspartate--tRNA ligase homolog F10M23.210 - Arabidopsis thaliana
>gi|4455210|emb|CAB36533.1| (AL035440) putative
aspartate-tRNA ligase [Arabidopsis thaliana]
>gi|7269540|emb|CAB79542.1| (AL161566) putative
aspartate-tRNA ligase [Arabidopsis thaliana]
Length = 504
Score = 191 bits (481), Expect = 1e-47
Identities = 139/452 (30%), Positives = 237/452 (51%), Gaps = 39/452 (8%)
Query: 3 EKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFET 62
E T ++ E+ G V + G ++ N VG K+F+ +R+S +Q V+ + VG ++ +
Sbjct: 72 ELTDVSNLVEEIVGSEVSIRGRLHKNRLVGTKLFVILRESGFTVQCVVEETRVGANMIKF 131
Query: 63 AKKLGRESSVIVEGIVKADERAPGGA----EVHVEKLKVI-QAVSEFPI--------PEN 109
K+L RES V + G+V ++ G E+HV K+ + +++ P+ +
Sbjct: 132 VKQLSRESVVELIGVVSHPKKPLTGTTQQVEIHVRKMYCLSRSLPNLPLVVEDAARSESD 191
Query: 110 PEQASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEG 169
E++ + L+ R L IR+P AI R++ + +A RE+L +G+ E+ P L+ G+ EG
Sbjct: 192 IEKSGKDTRLNNRVLDIRTPANQAIFRIQCQVQIAFREYLQSKGFLEIHTPKLIAGSSEG 251
Query: 170 GATLFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLE 228
G+ +F+L Y + A L+QS QL+ + AI G + +V+ + P FRAE S T RHL EF L+
Sbjct: 252 GSAVFRLDYKGQPACLAQSPQLHKQMAICGDMRRVFEVGPVFRAEDSFTHRHLCEFVGLD 311
Query: 229 LEAAW-MDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEA 287
+E M +IM + EL ++ + E KE+E R PF
Sbjct: 312 VEMEIRMHYSEIMDLVGELFPFIFTKIEERCPKELESVRKQY--------PF-------- 355
Query: 288 IEILQSKGVKIEWGDDMGADEERVLTQ----EFDRPFFV-YGYPKHIKAFYMKEDPNDPR 342
+ L+ G +++ D+ + ER L Q ++ F++ + YP ++ FY ND
Sbjct: 356 -QSLKEAGEEVDPLGDLNTESERKLGQLVLEKYKTEFYMLHRYPSAVRPFYTMPYENDSN 414
Query: 343 KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGF 402
+ D+ EI+ G++R + + L +R +E G+D K Y+D +YG+ PH GF
Sbjct: 415 YSNSFDVFIRGE--EIMSGAQRIHDPELLEKRARECGIDVKTISTYIDAFRYGAPPHGGF 472
Query: 403 GLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
G+G+ER+V + L++IR +LFPR R+ P
Sbjct: 473 GVGLERVVMLLCALNNIRKTSLFPRDSQRLTP 504
>sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68531|pir||SYRTDT aspartate--tRNA ligase (EC
6.1.1.12) - rat >gi|203066|gb|AAA40789.1| (J04487)
aspartyl-tRNA synthetase [Rattus norvegicus]
>gi|1773257|gb|AAC52981.1| (U30812) aspartyl-tRNA
synthetase [Rattus norvegicus]
Length = 501
Score = 190 bits (478), Expect = 2e-47
Identities = 134/445 (30%), Positives = 234/445 (52%), Gaps = 44/445 (9%)
Query: 25 VYSNMRVGKKIFLWIRDSTGIIQTVIAK-NVVGEDVFETAKKLGRESSVIVEGIVKADER 83
V+++ GK+ FL +R +Q ++A + + + + A + +ES + VEGIV+ +
Sbjct: 66 VHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIIDVEGIVRKVNQ 125
Query: 84 APGGA-----EVHVEKLKVIQAVSEFPIPENPEQA---------------SPELLLDYRH 123
G E+HV+K+ VI +++E +P + A + + LD R
Sbjct: 126 KIGSCTQQDVELHVQKIYVI-SLAEPRLPLQLDDAIRPEVEGEEDGRATVNQDTRLDNRI 184
Query: 124 LHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVA 183
+ +R+ AI ++ + RE L+ +G+ E+ P +++ A EGGA +F + YF A
Sbjct: 185 IDLRTSTSQAIFHLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKSNA 244
Query: 184 YLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKV 242
YL+QS QLY + I EKV+ + P FRAE S T RHLTEF L++E A+ + +V
Sbjct: 245 YLAQSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFN--YHYHEV 302
Query: 243 EEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEP--------PFPRISYDEAIEILQSK 294
EE+ +VQ L+ E F+ ++ T+ P P R+ Y EA+ +L+
Sbjct: 303 VEEIADTLVQIFKGLQ----ERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREA 358
Query: 295 GVKIEWGDDMGADEERVL----TQEFDRPFFVYG-YPKHIKAFYMKEDPNDPRKVLAADM 349
GV+++ +D+ E++L +++D F+V YP ++ FY DP +P++ + DM
Sbjct: 359 GVEMDDEEDLSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDM 418
Query: 350 LAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERL 409
EI+ G++R + L +R G+D + + Y+D ++G+ PH+G G+G+ER+
Sbjct: 419 FMRGE--EILSGAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERV 476
Query: 410 VAWVLKLDHIRWATLFPRTPARIYP 434
L L ++R ++FPR P R+ P
Sbjct: 477 TMLFLGLHNVRQTSMFPRDPKRLTP 501
>gi|6319872 Asn-tRNA synthetase; Ycr024cp [Saccharomyces cerevisiae]
>gi|135160|sp|P25345|SYNM_YEAST ASPARAGINYL-TRNA
SYNTHETASE, MITOCHONDRIAL PRECURSOR (ASPARAGINE--TRNA
LIGASE) (ASNRS) >gi|83213|pir||S19435 hypothetical
protein YCR024c - yeast (Saccharomyces cerevisiae)
>gi|1907168|emb|CAA42316.1| (X59720) YCR024c, len:492
[Saccharomyces cerevisiae]
Length = 492
Score = 187 bits (471), Expect = 2e-46
Identities = 137/456 (30%), Positives = 226/456 (49%), Gaps = 46/456 (10%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGIV 78
+ + GW+ S + + FL ++D T + I + D + K L ++ +
Sbjct: 34 ISINGWIKSIRLLKRIAFLDLQDGTSVNPLRIVIPLTNTDEVQFLKILKTGQTLSISNAT 93
Query: 79 ---KADERAPGGAEVH--VEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRSPKVSA 133
+ + P ++ V+ +K++ VSE P + + L L R+ +SA
Sbjct: 94 WQSTPNRKQPFELQIKNPVKSIKLVGPVSE-NYPLQKKYQTLRYLRSLPTLKYRTAYLSA 152
Query: 134 IMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK---------YFDKVAY 184
I+R++ + + + + +V PPIL + EG LF++ YF K Y
Sbjct: 153 ILRLRSFVEFQFMLYFQKNHFTKVSPPILTSNDCEGAGELFQVSTNTSPTASSYFGKPTY 212
Query: 185 LSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD-LWDIMKVE 243
L+ S QL+LE L + W+L+P FRAEKS T RHL+EFW LE+E +++ + ++
Sbjct: 213 LTVSTQLHLEILALSLSRCWTLSPCFRAEKSDTPRHLSEFWMLEVEMCFVNSVNELTSFV 272
Query: 244 EELVSYMVQRTL----ELRKKEIEMFRD-----DLTTLKNTE-----------PPFPRIS 283
E + ++++ + EL K+ ++ +L+ + T+ + I+
Sbjct: 273 ETTIKHIIKACIDNQQELLPKQFISSQENNASSELSINQETQQIKTRWEDLINEKWHNIT 332
Query: 284 YDEAIEILQSKGVKI-------EWGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMK 335
Y AIEIL+ + ++ +WG + + E+ L E F P FV YP+ K FYMK
Sbjct: 333 YTNAIEILKKRHNEVSHFKYEPKWGQPLQTEHEKFLAGEYFKSPVFVTDYPRLCKPFYMK 392
Query: 336 EDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPK-DYEWYLDLRKY 394
++ V D+L P G GEIIGGS RED+YDKL + +K GM+ + +WY+ LRK
Sbjct: 393 QNSTPDDTVGCFDLLVP-GMGEIIGGSLREDDYDKLCREMKARGMNRSGELDWYVSLRKE 451
Query: 395 GSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPA 430
GS PH GFGLG ER ++++ +I+ A F RT A
Sbjct: 452 GSAPHGGFGLGFERFISYLYGNHNIKDAIPFYRTSA 487
>gb|AAF58445.1| (AE003820) Aats-asp gene product [Drosophila melanogaster]
Length = 531
Score = 187 bits (469), Expect = 3e-46
Identities = 134/446 (30%), Positives = 234/446 (52%), Gaps = 33/446 (7%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAK-NVVGEDVFETAKKLGRESSVIVEG- 76
V + G V+++ GK+ FL +R + +Q ++A +V+ + + + A + +ES + ++
Sbjct: 89 VWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNIPKESIIDIQAK 148
Query: 77 ----IVKADERAPGGAEVHVEKLKVI-QAVSEFPI-------PENPEQA-------SPEL 117
K + E+ VE++ VI QA ++ P+ PEN + A + +
Sbjct: 149 PVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDAEGLNIRVNQDT 208
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
LD R L +R+P AI R++ + R+ L +G+ E+ P +++ A EGGA +F +
Sbjct: 209 RLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAASEGGANVFTVS 268
Query: 178 YFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
YF AYL+QS QLY + AI +KV+++ FRAE S T RHLTEF L+LE A+
Sbjct: 269 YFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFVGLDLEMAFKYH 328
Query: 237 W-DIMKVEEELVSYMVQRTLELRKKEIEMFRDD--LTTLKNTEPPFPRISYDEAIEILQS 293
+ +++ + + + + KEIE + K EPP + + + + +L+
Sbjct: 329 YHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPLI-LQFADGVAMLRE 387
Query: 294 KGVKIEWGDDMGADEERVLTQ----EFDRPFFVYG-YPKHIKAFYMKEDPNDPRKVLAAD 348
GV+ +D+ E++L + ++D F++ +P I+ FY DPN+P + D
Sbjct: 388 AGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTMPDPNNPVYSNSYD 447
Query: 349 MLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVER 408
M EI+ G++R + + L++R K G+D Y++ +YG PH+G G+G+ER
Sbjct: 448 MFMRGE--EILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCPPHAGGGIGMER 505
Query: 409 LVAWVLKLDHIRWATLFPRTPARIYP 434
+V L LD+IR ++FPR P R+ P
Sbjct: 506 VVMLYLGLDNIRKTSMFPRDPKRLTP 531
>gb|AAF57921.1| (AE003804) CG6796 gene product [Drosophila melanogaster]
Length = 460
Score = 186 bits (467), Expect = 5e-46
Identities = 134/454 (29%), Positives = 221/454 (48%), Gaps = 46/454 (10%)
Query: 8 QDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRD--STGIIQTVIAKNVVGEDVFETAKK 65
Q +K G + + GW+ + R+ FL I D ++ Q V+ + T +
Sbjct: 16 QILKTNKPGDSLAIQGWIKNVRRLKNNTFLDINDGSTSSRFQVVVPR---------TPEN 66
Query: 66 LGRESSVIVEGIVKADERAPGGAEVHVEKLKVI-QAVSEFPIPENPEQASP-ELLLDYRH 123
++ + K G E+H +++++ + + P +P+Q P E + ++ H
Sbjct: 67 QHLAPGSVIAAVGKIQVAPNGSFELHANQVEMLAEGRLQEGYPFSPKQKHPPEYVREHLH 126
Query: 124 LHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK------ 177
L R V+A MRV+ A +++ + + ++ P+L T EG +F+++
Sbjct: 127 LRSRVDFVAAQMRVRHKAQKAIHDYMDDQDFVQINTPLLTTNDCEGAGEVFRVQPDSQDL 186
Query: 178 --------------YFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTE 223
YFD +LS S QL+LEA +GL K ++L+P+FRAE S++ HL E
Sbjct: 187 LKQMNRPNIPMEQSYFDSKVFLSVSGQLHLEAMTYGLGKTYTLSPAFRAENSKSPLHLAE 246
Query: 224 FWHLELEAAWM-DLWDIMKVEEELVSYMVQRTLELRKKEIEMFR---DDLTTLKNTEPPF 279
F+ E E A + ++ + + E+++ + R LE +++ + + + L + P+
Sbjct: 247 FYMFEAELAHLEEMEKLAQFIEQMLKSVTNRLLETSGEDLSFCQRNSNSNSDLPWLQVPW 306
Query: 280 PRISYDEAIEILQ----SKGVKIEWGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMK 335
+SYDEA+++LQ S I + D+E L P FV +P K FYMK
Sbjct: 307 KIMSYDEALQVLQENKDSLKTPISLNEGFSKDQELFLVAHCGAPVFVVDWPAQQKPFYMK 366
Query: 336 EDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYG 395
++P +V A D+L P GE+ GGS RE D + +K PKD EWY+DLRKYG
Sbjct: 367 VSRSNPNRVHALDLLMP-AVGELCGGSLRES--DPAI--LKSHPHLPKDLEWYVDLRKYG 421
Query: 396 SVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTP 429
VP GFG+G ER + V + +IR FPR P
Sbjct: 422 GVPTGGFGMGFERYLQLVTGVKNIRDVIPFPRYP 455
>gb|AAD21582.1| (AF113612) aspartyl tRNA synthetase [Drosophila melanogaster]
Length = 531
Score = 184 bits (463), Expect = 1e-45
Identities = 133/446 (29%), Positives = 233/446 (51%), Gaps = 33/446 (7%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAK-NVVGEDVFETAKKLGRESSVIVEG- 76
V + G V+++ GK+ FL +R + +Q ++A +V+ + + + A + +ES + ++
Sbjct: 89 VWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNIPKESIIDIQAK 148
Query: 77 ----IVKADERAPGGAEVHVEKLKVI-QAVSEFPI-------PENPEQA-------SPEL 117
K + E+ VE++ VI QA ++ P+ PEN + A + +
Sbjct: 149 PVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDAEGLNIRVNQDT 208
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
LD R L +R+P AI R++ + R+ L +G+ E+ P +++ A EGGA +F +
Sbjct: 209 RLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAASEGGANVFTVS 268
Query: 178 YFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
YF AYL+QS QLY + AI +KV+++ FRAE S T RHLTEF L+LE A+
Sbjct: 269 YFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFVGLDLEMAFKYH 328
Query: 237 W-DIMKVEEELVSYMVQRTLELRKKEIEMFRDD--LTTLKNTEPPFPRISYDEAIEILQS 293
+ +++ + + + + KEIE + K EPP + + + + +L+
Sbjct: 329 YHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPLI-LQFADGVAMLRE 387
Query: 294 KGVKIEWGDDMGADEERVLTQ----EFDRPFFVYG-YPKHIKAFYMKEDPNDPRKVLAAD 348
GV+ +D+ E++L + ++D F++ +P I+ FY DPN+P + D
Sbjct: 388 AGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTMPDPNNPVYSNSYD 447
Query: 349 MLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVER 408
M EI+ G++R + + L++R K G+D Y++ +YG PH+G G+G+ER
Sbjct: 448 MFMRGE--EILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCPPHAGGGIGMER 505
Query: 409 LVAWVLKLDHIRWATLFPRTPARIYP 434
+V L LD+IR ++ PR P R+ P
Sbjct: 506 VVMLYLGLDNIRKTSMLPRDPKRLTP 531
>gi|6323011 Aspartyl-tRNA synthetase, cytosolic; Dps1p [Saccharomyces
cerevisiae] >gi|135100|sp|P04802|SYDC_YEAST
ASPARTYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARTATE--TRNA
LIGASE) (ASPRS) >gi|68532|pir||SYBYDC aspartate--tRNA
ligase (EC 6.1.1.12), cytosolic [validated] - yeast
(Saccharomyces cerevisiae) >gi|3370|emb|CAA27269.1|
(X03606) AspRS (aa 1-557) [Saccharomyces cerevisiae]
>gi|3411|emb|CAA29865.1| (X06665) aspartyl tRNA synthase
[Saccharomyces cerevisiae] >gi|1297012|emb|CAA66172.1|
(X97560) aspartyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1360191|emb|CAA97464.1| (Z73123) ORF
YLL018c [Saccharomyces cerevisiae]
Length = 557
Score = 181 bits (455), Expect = 1e-44
Identities = 137/454 (30%), Positives = 229/454 (50%), Gaps = 39/454 (8%)
Query: 17 KRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKN---VVGEDVFETAKKLGRESSV 72
K V V++ + G + FL +R +IQ ++ N + +++ + A L ES V
Sbjct: 107 KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 166
Query: 73 IVEGIVKADERAPGGA-----EVHVEKLKVIQAVSEFPIPENPEQASP------------ 115
+V GIVK + A E+H+ K+ I E +P E AS
Sbjct: 167 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPE-ALPILLEDASRSEAEAEAAGLPV 225
Query: 116 ---ELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT 172
+ LDYR + +R+ AI R++ + RE+L + + EV P L+ EGG++
Sbjct: 226 VNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSS 285
Query: 173 LFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEA 231
+F++ YF AYL+QS Q + I E+V+ + P FRAE S T RH+TEF L++E
Sbjct: 286 VFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEM 345
Query: 232 AWMDLW-DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPP---FPRISYDEA 287
A+ + + +++ EL ++ + EIE+ R + P R++Y E
Sbjct: 346 AFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEG 405
Query: 288 IEILQSKGVKIEWGDDMGADEERVLTQ----EFDRPFFVYG-YPKHIKAFYMKEDPNDPR 342
IE+L++ G +I +D+ + E+ L + ++D F++ +P I+ FY DP +P+
Sbjct: 406 IEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPK 465
Query: 343 KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKD--YEWYLDLRKYGSVPHS 400
+ D EI+ G++R ++ L +R+K G+ P+D + Y D YG PH+
Sbjct: 466 YSNSYDFFMRGE--EILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHA 523
Query: 401 GFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
G G+G+ER+V + L L +IR A+LFPR P R+ P
Sbjct: 524 GGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP 557
>pdb|1ASZ|A Chain A, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.12) Complexed
With Transfer Ribonucleic Acid (Trnaasp) And Atp
>gi|1064988|pdb|1ASZ|B Chain B, Aspartyl Trna Synthetase
(Asprs) (E.C.6.1.1.12) Complexed With Transfer
Ribonucleic Acid (Trnaasp) And Atp
>gi|1064982|pdb|1ASY|A Chain A, Aspartyl Trna Synthetase
(Asprs) (E.C.6.1.1.12) Complexed With Transfer
Ribonucleic Acid (Trnaasp) >gi|1064984|pdb|1ASY|B Chain
B, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.12)
Complexed With Transfer Ribonucleic Acid (Trnaasp)
Length = 490
Score = 181 bits (455), Expect = 1e-44
Identities = 137/454 (30%), Positives = 229/454 (50%), Gaps = 39/454 (8%)
Query: 17 KRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKN---VVGEDVFETAKKLGRESSV 72
K V V++ + G + FL +R +IQ ++ N + +++ + A L ES V
Sbjct: 40 KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 99
Query: 73 IVEGIVKADERAPGGA-----EVHVEKLKVIQAVSEFPIPENPEQASP------------ 115
+V GIVK + A E+H+ K+ I E +P E AS
Sbjct: 100 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPE-ALPILLEDASRSEAEAEAAGLPV 158
Query: 116 ---ELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT 172
+ LDYR + +R+ AI R++ + RE+L + + EV P L+ EGG++
Sbjct: 159 VNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSS 218
Query: 173 LFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEA 231
+F++ YF AYL+QS Q + I E+V+ + P FRAE S T RH+TEF L++E
Sbjct: 219 VFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEM 278
Query: 232 AWMDLW-DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPP---FPRISYDEA 287
A+ + + +++ EL ++ + EIE+ R + P R++Y E
Sbjct: 279 AFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEG 338
Query: 288 IEILQSKGVKIEWGDDMGADEERVLTQ----EFDRPFFVYG-YPKHIKAFYMKEDPNDPR 342
IE+L++ G +I +D+ + E+ L + ++D F++ +P I+ FY DP +P+
Sbjct: 339 IEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPK 398
Query: 343 KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKD--YEWYLDLRKYGSVPHS 400
+ D EI+ G++R ++ L +R+K G+ P+D + Y D YG PH+
Sbjct: 399 YSNSYDFFMRGE--EILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHA 456
Query: 401 GFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
G G+G+ER+V + L L +IR A+LFPR P R+ P
Sbjct: 457 GGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP 490
>pdb|1EOV|A Chain A, Free Aspartyl-Trna Synthetase (Asprs) (E.C. 6.1.1.12) From
Yeast
Length = 487
Score = 181 bits (455), Expect = 1e-44
Identities = 137/454 (30%), Positives = 229/454 (50%), Gaps = 39/454 (8%)
Query: 17 KRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIAKN---VVGEDVFETAKKLGRESSV 72
K V V++ + G + FL +R +IQ ++ N + +++ + A L ES V
Sbjct: 37 KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 96
Query: 73 IVEGIVKADERAPGGA-----EVHVEKLKVIQAVSEFPIPENPEQASP------------ 115
+V GIVK + A E+H+ K+ I E +P E AS
Sbjct: 97 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPE-ALPILLEDASRSEAEAEAAGLPV 155
Query: 116 ---ELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT 172
+ LDYR + +R+ AI R++ + RE+L + + EV P L+ EGG++
Sbjct: 156 VNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSS 215
Query: 173 LFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEA 231
+F++ YF AYL+QS Q + I E+V+ + P FRAE S T RH+TEF L++E
Sbjct: 216 VFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEM 275
Query: 232 AWMDLW-DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPP---FPRISYDEA 287
A+ + + +++ EL ++ + EIE+ R + P R++Y E
Sbjct: 276 AFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEG 335
Query: 288 IEILQSKGVKIEWGDDMGADEERVLTQ----EFDRPFFVYG-YPKHIKAFYMKEDPNDPR 342
IE+L++ G +I +D+ + E+ L + ++D F++ +P I+ FY DP +P+
Sbjct: 336 IEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPK 395
Query: 343 KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKD--YEWYLDLRKYGSVPHS 400
+ D EI+ G++R ++ L +R+K G+ P+D + Y D YG PH+
Sbjct: 396 YSNSYDFFMRGE--EILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHA 453
Query: 401 GFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
G G+G+ER+V + L L +IR A+LFPR P R+ P
Sbjct: 454 GGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP 487
>pir||T10672 aspartate--tRNA ligase homolog F6E21.100 - Arabidopsis thaliana
>gi|7270020|emb|CAB79836.1| (AL161578) aspartate--tRNA
ligase-like protein [Arabidopsis thaliana]
Length = 558
Score = 180 bits (451), Expect = 4e-44
Identities = 146/468 (31%), Positives = 241/468 (51%), Gaps = 39/468 (8%)
Query: 3 EKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKI-FLWIRDSTGIIQTVIA---KNVVGED 58
E T D+ E+ V + G V++N K+ F+ +R+S +Q V++ K VG +
Sbjct: 94 EWTDVSDLVEEMLESEVLIRGRVHTNRPTSNKLGFVVLRESGSTVQCVVSQSEKTKVGAN 153
Query: 59 VFETAKKLGRESSVIVEGIVKADERAPGGA----EVHVEKLKVIQ-------------AV 101
+ + K+L RES V V G+V + G E+ V K+ I A
Sbjct: 154 MVKYLKQLSRESFVDVIGVVTLPKEPLTGTTQQVEIQVRKVYCINKSLAKLPLSVEDAAR 213
Query: 102 SEFPIPENPEQASP------ELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWH 155
SE I + + SP + L+YR L +R+P AI +++ + A RE L + +
Sbjct: 214 SEADIEASLQTPSPAARVNQDTRLNYRVLDLRTPANQAIFQLQYEVEYAFREKLRFKNFV 273
Query: 156 EVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEK 214
+ P L+ G+ EGG+ +F+L+Y + A L+QS QL+ + AI G L +V+ + P FRAE
Sbjct: 274 GIHTPKLMAGSSEGGSAVFRLEYKGQPACLAQSPQLHKQMAICGDLRRVFEVGPVFRAED 333
Query: 215 SRTRRHLTEFWHLELEAAWMDLW-DIMKVEEELVSYMVQRTLELRKKEIEMFRDD--LTT 271
S T RHL EF L++E + +IM + +EL ++ E KKE++
Sbjct: 334 SFTHRHLCEFVGLDVEMEIRKHYSEIMDLVDELFVFIFTSLNERCKKELQAVGKQYPFEP 393
Query: 272 LKNTEPPFPRISYDEAIEILQSKGVKIEWGDDMGADEERVLTQ----EFDRPFFV-YGYP 326
LK P R++++E +++L+ GV+++ D+ + ER L Q +++ F++ + YP
Sbjct: 394 LKFL-PKTLRLTFEEGVQMLKEAGVEVDPLGDLNTESERKLGQLVLEKYNTEFYILHRYP 452
Query: 327 KHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYE 386
K ++ FY ++P + D+ EII G++R + L QR E G+D K
Sbjct: 453 KAVRPFYTMTCADNPLYSNSFDVFIRGE--EIISGAQRVHIPEVLEQRAGECGIDVKTIS 510
Query: 387 WYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
Y+D +YG+ H GFG+G+ER+V L++IR +LFPR P R+ P
Sbjct: 511 TYIDSFRYGAPLHGGFGVGLERVVMLFCALNNIRKTSLFPRDPQRLSP 558
>sp|Q03577|SYD_CAEEL PROBABLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|280519|pir||S28278 aspartate--tRNA ligase (EC
6.1.1.12) [similarity] - Caenorhabditis elegans
>gi|3873792|emb|CAA79536.1| (Z19152) putative
Aspartyl-tRNA synthetase, contains similarity to Pfam
domain: PF00152 (tRNA synthetases class II (D, K and
N)), Score=579.2, E-value=8.2e-171, N=1; PF01336
(Aspartyl-tRNA synthetase (AspRS), N terminus),
Score=345.6, E-value=1.7e-100,>
Length = 531
Score = 179 bits (450), Expect = 5e-44
Identities = 137/453 (30%), Positives = 223/453 (48%), Gaps = 38/453 (8%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNV-VGEDVFETAKKLGRESSVIVE 75
K V + G +++ GK FL +R +Q + N + + + + + +ES V V
Sbjct: 82 KDVWVRGRIHTTRSKGKNCFLVLRQGVYTVQVAMFMNEKISKQMLKFVSSISKESIVDVY 141
Query: 76 GIV-KADERAPGGAEVHVEKLK-----VIQAVSEFPI---------PENPEQASPE---- 116
+ K D + VE L V + + P+ P + E+AS +
Sbjct: 142 ATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRRAPTDEEKASEQENQL 201
Query: 117 ------LLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGG 170
LD R + +R+P AI R++ + R L G+ E+ P +++ EGG
Sbjct: 202 AVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFVEIMAPKIISAPSEGG 261
Query: 171 ATLFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLEL 229
A +F++ YF AYL+QS QLY + AI G EKV+++ P FRAE S T RH+TEF L+L
Sbjct: 262 ANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDL 321
Query: 230 EAAW-MDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTT--LKNTEPPFPRISYDE 286
E A+ ++M+ E+++ M + + + EI + + EPP + Y +
Sbjct: 322 EMAFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQYPAEPFQFCEPPLI-LKYPD 380
Query: 287 AIEILQSKGVKIEWGDDMGADEERVL----TQEFDRPFFVYG-YPKHIKAFYMKEDPNDP 341
AI +L+ G++I DD+ E+ L +++ F+V +P ++ FY D +D
Sbjct: 381 AITLLRENGIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHDE 440
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSG 401
R + DM EI+ G++R + D LV+R K +D + Y+D KYG PH+G
Sbjct: 441 RYSNSYDMFMRGE--EILSGAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAG 498
Query: 402 FGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
G+G+ER+ L L +IR A+LFPR P R+ P
Sbjct: 499 GGIGLERVTMLFLGLHNIRLASLFPRDPKRLTP 531
>dbj|BAA35676.1| (D90730) Asparaginyl-tRNA synthetase (EC 6.1.1.22)
(asparagine-tRNA ligase) (asnRS). [Escherichia coli]
Length = 221
Score = 172 bits (432), Expect = 6e-42
Identities = 97/218 (44%), Positives = 139/218 (63%), Gaps = 13/218 (5%)
Query: 223 EFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMF-----RDDLTTLKN-TE 276
EFW LE E A+ +L DI + E ++ Y+ + LE R +++ F +D ++ L+ E
Sbjct: 1 EFWMLEPEVAFANLNDIAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIE 60
Query: 277 PPFPRISYDEAIEILQSKGVKIE----WGDDMGADEERVLTQE-FDRPFFVYGYPKHIKA 331
F ++ Y +A+ IL++ G K E WG D+ ++ ER L +E F P V YPK IKA
Sbjct: 61 ADFAQVDYTDAVTILENCGRKFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKA 120
Query: 332 FYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDL 391
FYM+ + D + V A D+LAP G GEIIGGS+RE+ D L +R+ E G++ +DY WY DL
Sbjct: 121 FYMRLN-EDGKTVAAMDVLAP-GIGEIIGGSQREERLDVLDERMLEMGLNKEDYWWYRDL 178
Query: 392 RKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTP 429
R+YG+VPHSGFGLG ERL+A+V + ++R FPRTP
Sbjct: 179 RRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTP 216
>dbj|BAB15655.1| (AK027094) unnamed protein product [Homo sapiens]
Length = 250
Score = 157 bits (393), Expect = 2e-37
Identities = 94/244 (38%), Positives = 141/244 (57%), Gaps = 21/244 (8%)
Query: 202 KVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD-LWDIMKVEEELVSYMVQRTLELRKK 260
+V++ P+FRAE S++RRHL EF+ +E E +++D L D+M+V EEL L +
Sbjct: 7 QVFTFGPTFRAENSQSRRHLAEFYMIEAEISFVDSLQDLMQVIEELFKATTMMVLSKCPE 66
Query: 261 EIEMFRDDLTT---------LKNTEPPFPRISYDEAIEILQSKGVKI----EWGDDMGAD 307
++E+ + LKN F ISY EA+EIL+ EWG D+ +
Sbjct: 67 DVELCHKFIAPGQKDRLEHMLKNN---FLIISYTEAVEILKQASQNFTFTPEWGADLRTE 123
Query: 308 EERVLTQEFDR-PFFVYGYPKHIKAFYMKEDPNDPRKVLAA-DMLAPEGYGEIIGGSERE 365
E+ L + P FV YP +K FYM+++ + P+ +AA D+L P G GE+ GG RE
Sbjct: 124 HEKYLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLVP-GVGELFGGGLRE 182
Query: 366 DNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLF 425
+ Y L +R+ G+ + Y+WYLDLR++GSVPH GFG+G ER + +L +D+I+ F
Sbjct: 183 ERYHFLEERLARSGLT-EVYQWYLDLRRFGSVPHGGFGIGFERYLQCILGVDNIKDVIPF 241
Query: 426 PRTP 429
PR P
Sbjct: 242 PRFP 245
>pir||S70779 asparagine--tRNA ligase (EC 6.1.1.22) - Xenorhabdus nematophilus
(fragment)
Length = 192
Score = 150 bits (376), Expect = 2e-35
Identities = 81/170 (47%), Positives = 117/170 (68%), Gaps = 8/170 (4%)
Query: 266 RDDLTTL-KNTEPPFPRISYDEAIEILQSKGVKIE----WGDDMGADEERVLTQE-FDRP 319
+D +T L K + F ++ Y +AI+IL++ G K E WG D+ ++ ER L ++ F+ P
Sbjct: 13 KDVITRLEKFVDSDFIQLDYTDAIKILENCGQKFENPYFWGVDLSSEHERYLAEKHFEAP 72
Query: 320 FFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEG 379
+ YPK+IKAFYM+ + D + V A D+LAP G GEIIGGS+RE+ D L +R++E G
Sbjct: 73 VIMKNYPKNIKAFYMRMN-EDGKTVAAMDVLAP-GIGEIIGGSQREERLDMLDKRLEEMG 130
Query: 380 MDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTP 429
++ +DY WY DLR+YG+VPH+GFGLG ERLVA+V + ++R FPRTP
Sbjct: 131 LNKEDYWWYRDLRRYGTVPHAGFGLGFERLVAYVTGVANVRDVIPFPRTP 180
>emb|CAC11748.1| (AL445064) asparagine--tRNA ligase related protein [Thermoplasma
acidophilum]
Length = 329
Score = 145 bits (362), Expect = 1e-33
Identities = 83/314 (26%), Positives = 162/314 (51%), Gaps = 23/314 (7%)
Query: 125 HIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEG-GATLFK--LKYFDK 181
H+ P++ ++V+ ++ E+L G+ EV PP++++ + +F + Y+
Sbjct: 31 HLEKPELYHALKVQSSIRSITSEFLKERGFIEV-PPVIISVLTDPLNHPVFDPTIDYYGY 89
Query: 182 VAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAE---KSRTRRHLTEFWHLELEAAWMDLWD 238
L++S + +++++ +P+ R E K +T RHL EF L+LE +
Sbjct: 90 KYSLTKSMIFHKHLLTKHFDRIFTFSPNIRLEEEDKVKTGRHLAEFTQLDLEMKGASRDE 149
Query: 239 IMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKI 298
+M + E+++ + ++ +++++ F DL + PF RI+Y +A +
Sbjct: 150 VMSLGEDMIIDLFKKIKRSNEEDLKFFGRDL---RIPSKPFKRIAYLDAYK--------- 197
Query: 299 EWGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEI 358
G D E +L+ E PF++ P + FY +EDP+ P ++ D++ PEG+GE
Sbjct: 198 ----QYGEDFEHILSSEMKEPFWIIDIPLEKREFYDREDPSRPGILVDMDLIYPEGFGEA 253
Query: 359 IGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDH 418
+ G ERE +++ RI +G + ++WY++ K G +P +GFG+G+ERL ++ L+
Sbjct: 254 LSGGEREYELSRIIDRIHRKGQTEEQFKWYIEFAKEGLMPSAGFGIGIERLTRFICGLER 313
Query: 419 IRWATLFPRTPARI 432
I A FP+ P +
Sbjct: 314 IEDAHPFPKIPGHL 327
>emb|CAA10905.1| (AJ222645) asparaginyl-tRNA synthetase [Arabidopsis thaliana]
Length = 276
Score = 144 bits (360), Expect = 2e-33
Identities = 92/267 (34%), Positives = 139/267 (51%), Gaps = 14/267 (5%)
Query: 174 FKLKYFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAW 233
F +F + YL+ S + +LE+ L KV++ P F A+K RHL E W++E E A+
Sbjct: 6 FSKDFFGRDTYLTASGRFHLESYASALGKVYTFGPRFIADKIDNARHLAEKWNVETEMAF 65
Query: 234 MDLWDIMKVEEELVSYMVQRTLELRKKEIEMF--RDDLTTLKNTEPPFP----RISYDEA 287
+L D M +E ++ + LE R ++++ R D T E R SY E
Sbjct: 66 AELDDAMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYTEV 125
Query: 288 IEILQSKGV-----KIEWGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDP 341
I +LQ K EWG + + LT E + P V+ YPK IK FY++ ND
Sbjct: 126 ISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGPVIVHTYPKAIKQFYVRL--NDD 183
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSG 401
+K +AA L G +I GS+ E+ ++ L RI E G + +EWYLDLR++G+V HSG
Sbjct: 184 KKTVAAFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGTVKHSG 243
Query: 402 FGLGVERLVAWVLKLDHIRWATLFPRT 428
L +E+++ + L I+ A FPR+
Sbjct: 244 ISLSMEQMLLYATGLPDIKDAIPFPRS 270
>gb|AAD46682.1|AF170910_1 (AF170910) SYNC2 protein [Arabidopsis thaliana]
Length = 638
Score = 144 bits (360), Expect = 2e-33
Identities = 92/267 (34%), Positives = 139/267 (51%), Gaps = 14/267 (5%)
Query: 174 FKLKYFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAW 233
F +F + YL+ S + +LE+ L KV++ P F A+K RHL E W++E E A+
Sbjct: 368 FSKDFFGRDTYLTASGRFHLESYASALGKVYTFGPRFIADKIDNARHLAEKWNVETEMAF 427
Query: 234 MDLWDIMKVEEELVSYMVQRTLELRKKEIEMF--RDDLTTLKNTEPPFP----RISYDEA 287
+L D M +E ++ + LE R ++++ R D T E R SY E
Sbjct: 428 AELDDAMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYTEV 487
Query: 288 IEILQSKGV-----KIEWGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDP 341
I +LQ K EWG + + LT E + P V+ YPK IK FY++ ND
Sbjct: 488 ISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGPVIVHTYPKAIKQFYVRL--NDD 545
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSG 401
+K +AA L G +I GS+ E+ ++ L RI E G + +EWYLDLR++G+V HSG
Sbjct: 546 KKTVAAFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGTVKHSG 605
Query: 402 FGLGVERLVAWVLKLDHIRWATLFPRT 428
L +E+++ + L I+ A FPR+
Sbjct: 606 ISLSMEQMLLYATGLPDIKDAIPFPRS 632
>gb|AAF02166.1|AC009853_26 (AC009853) putative asparaginyl-tRNA synthetase [Arabidopsis
thaliana]
Length = 638
Score = 144 bits (360), Expect = 2e-33
Identities = 92/267 (34%), Positives = 139/267 (51%), Gaps = 14/267 (5%)
Query: 174 FKLKYFDKVAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAW 233
F +F + YL+ S + +LE+ L KV++ P F A+K RHL E W++E E A+
Sbjct: 368 FSKDFFGRDTYLTASGRFHLESYASALGKVYTFGPRFIADKIDNARHLAEKWNVETEMAF 427
Query: 234 MDLWDIMKVEEELVSYMVQRTLELRKKEIEMF--RDDLTTLKNTEPPFP----RISYDEA 287
+L D M +E ++ + LE R ++++ R D T E R SY E
Sbjct: 428 AELDDAMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYTEV 487
Query: 288 IEILQSKGV-----KIEWGDDMGADEERVLTQE-FDRPFFVYGYPKHIKAFYMKEDPNDP 341
I +LQ K EWG + + LT E + P V+ YPK IK FY++ ND
Sbjct: 488 ISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGPVIVHTYPKAIKQFYVRL--NDD 545
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSG 401
+K +AA L G +I GS+ E+ ++ L RI E G + +EWYLDLR++G+V HSG
Sbjct: 546 KKTVAAFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGTVKHSG 605
Query: 402 FGLGVERLVAWVLKLDHIRWATLFPRT 428
L +E+++ + L I+ A FPR+
Sbjct: 606 ISLSMEQMLLYATGLPDIKDAIPFPRS 632
>pir||S77842 probable asparagine--tRNA ligase (EC 6.1.1.22) - Mycoplasma
capricolum (fragment) >gi|530408|emb|CAA83705.1|
(Z33026) Asn-tRNA synthetase [Mycoplasma capricolum]
Length = 172
Score = 137 bits (342), Expect = 2e-31
Identities = 78/173 (45%), Positives = 111/173 (64%), Gaps = 13/173 (7%)
Query: 269 LTTLKNTEPPFPRISYDEAIEILQ---SKGVK-----IEWGDDMGADEERVLTQEFDR-P 319
L +++N+E F +Y EAIEIL+ + G K IE+G D+G + ER + ++ ++ P
Sbjct: 2 LNSVRNSE--FKVTTYTEAIEILKQAVANGHKFEVSDIEFGLDLGTEHERYICEQVNKAP 59
Query: 320 FFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEG 379
FV YPK IKAFYMK++ D + V A D+L P G GE++GGS+REDNY+KL++R KE
Sbjct: 60 TFVTNYPKEIKAFYMKQN-EDNKTVAAVDLLVP-GIGELVGGSQREDNYEKLIKRCKEVN 117
Query: 380 MDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARI 432
+D EWY +LR YG +GFGLG ERL+ ++ +IR FPRTP +
Sbjct: 118 IDIDQLEWYNNLRLYGYYKSAGFGLGFERLIMYITGASNIRDVIPFPRTPKNL 170
>sp|Q56112|SYN_SALTI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1435180|emb|CAA61904.1| (X89757) asparaginyl-tRNA
synthetase [Salmonella typhi]
Length = 109
Score = 119 bits (296), Expect = 5e-26
Identities = 60/105 (57%), Positives = 77/105 (73%), Gaps = 2/105 (1%)
Query: 325 YPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKD 384
YPK IKAFYM+ + D + V A D+LAP G GEIIGGS+RE+ D L R+ E G++ +D
Sbjct: 2 YPKEIKAFYMRLN-EDGKTVAAMDVLAP-GIGEIIGGSQREERLDVLDARMAEMGLNKED 59
Query: 385 YEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTP 429
Y WY DLR+YG+VPHSGFGLG ERL+A+V + ++R FPRTP
Sbjct: 60 YWWYSDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTP 104
>dbj|BAB04971.1| (AP001511) aspartyl-tRNA synthetase [Bacillus halodurans]
Length = 595
Score = 114 bits (283), Expect = 2e-24
Identities = 81/300 (27%), Positives = 151/300 (50%), Gaps = 30/300 (10%)
Query: 1 MIEKTY-CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDV 59
MI +T+ C + E +RV+L GWV +G+ IF+ +RD +G++Q V + + ++
Sbjct: 1 MIGRTHHCGQLSEEQVNERVQLKGWVQRRRDLGQVIFVDLRDRSGVVQLVFNSD-ISQEA 59
Query: 60 FETAKKLGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIP-ENPE 111
ETA+K+ E + VEG+V D+ A G EVHVE+L ++ P E
Sbjct: 60 LETAEKVRNEYVLDVEGVVLKRDPSTVNDKIATGTIEVHVERLTILNKAKSLPFQIEANT 119
Query: 112 QASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGA 171
AS ++ L YR+L +R P + M+++ R++L + + E+ P+L EG
Sbjct: 120 DASEDIRLKYRYLDLRRPDMQETMKLRHQTTKLIRDFLDGQEFFEIETPMLTKSTPEGAR 179
Query: 172 TLF--KLKYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLE 228
+ + L QS Q++ + + G E+ + + FR E R R EF ++
Sbjct: 180 DYLVPSRVHHGEFYALPQSPQIFKQLLMVSGFERYYQIVRCFRDEDLRADRQ-PEFTQID 238
Query: 229 LEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
+E ++MD D++ + E +++ +++ E++ ++ + PFPR++YD+A+
Sbjct: 239 IETSFMDKEDLLTMTENMMAKIMK---EVKGLDVAL-------------PFPRMTYDDAM 282
>sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437581|pir||D69591 aspartate--tRNA ligase (EC
6.1.1.12) aspS - Bacillus subtilis
>gi|2635219|emb|CAB14714.1| (Z99118) aspartyl-tRNA
synthetase [Bacillus subtilis]
Length = 592
Score = 112 bits (278), Expect = 7e-24
Identities = 85/296 (28%), Positives = 149/296 (49%), Gaps = 32/296 (10%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC DI + G+ V L GWV +G IF+ +RD TGI+Q V + V ++ A+
Sbjct: 7 YCGDITEKAIGESVTLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPD-VSKEALAIAEG 65
Query: 66 LGRESSVIVEGIVKADERA-------PGGAEVHVEKLKVIQAVS--EFPIPENPEQASPE 116
+ E + ++G V A E G E+H + + V+ A F I + E+ S +
Sbjct: 66 IRNEYVLDIQGKVVAREEGTVNPNLKTGAIEIHADGVNVLNAAKTPPFAISDQAEEVSED 125
Query: 117 LLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT--LF 174
+ L +R+L +R P + M+++ + A R +L G+ ++ PIL TG+ GA L
Sbjct: 126 VRLKHRYLDLRRPAMFQTMQLRHNVTKAVRSFLDENGFLDIETPIL-TGSTPEGARDYLV 184
Query: 175 KLKYFDKVAY-LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAA 232
+ + Y L QS QL+ + + G+E+ + + FR E R R EF +++E +
Sbjct: 185 PSRVHEGEFYALPQSPQLFKQLLMVSGIERYYQIARCFRDEDLRADRQ-PEFTQIDIEMS 243
Query: 233 WMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
+M DIM + EE+++ +++ T + +E+++ P PR++YDEA+
Sbjct: 244 FMSQEDIMSLAEEMMAKVMRET---KGEELQL-------------PLPRMTYDEAM 283
>sp|O67258|SYK_AQUAE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437570|pir||G70403 lysine--tRNA ligase (EC 6.1.1.6)
- Aquifex aeolicus >gi|2983651|gb|AAC07218.1| (AE000728)
lysyl-tRNA synthetase [Aquifex aeolicus]
Length = 597
Score = 111 bits (276), Expect = 1e-23
Identities = 118/447 (26%), Positives = 207/447 (45%), Gaps = 52/447 (11%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVI-VEGI 77
V LAG + S +GK IF I+D TG IQ + K+V+GE+ + ++ V G
Sbjct: 154 VSLAGRLVSMRSMGKAIFGHIQDLTGKIQIYLKKDVIGEEKLKFFNDYIDVGDIVGVRG- 212
Query: 78 VKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLH---IRSPKVSAI 134
K G V VE+ +++ A S P+PE ++ + YR + I +P+ I
Sbjct: 213 -KLFRTNTGELTVEVEEYQLL-AKSLHPLPEK-WHGLKDVEVRYRQRYLDLIANPEARRI 269
Query: 135 MRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKL--KYFDKVAYLSQSAQLY 192
++ LI R++ G+ EV PIL A A F + + YL + +LY
Sbjct: 270 FMLRTKLITEMRKFFEMHGFIEVETPILQPIASGANARPFVTYHNFLETELYLRIAPELY 329
Query: 193 LEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMV 251
L+ I G +V+ + +FR E S R H EF +E AA+ D D++K E++ Y++
Sbjct: 330 LKRLIVGGFPRVYEIGKNFRNE-SVDRTHNPEFTMVEFYAAYWDYHDLIKFTEDMFVYLL 388
Query: 252 QRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEA---------------IEILQSKGV 296
++TL K + + D + PPF ++ Y + +E L+
Sbjct: 389 EKTLGTLKVKYGEWELDFS------PPFKKVRYFDLLKEKTGKDKDFFLKDLEGLRKLAK 442
Query: 297 KIEWGDDMGADEERVLTQEFDR--------PFFVYGYPKHIK--AFYMKEDPN--DPRKV 344
++E D ++L + F++ P FV +PK + A +EDP+ + ++
Sbjct: 443 ELEIPDVERMTHAKLLDKVFEKVAEEDLIQPTFVIDFPKILSPLAKTHREDPDLVERFEL 502
Query: 345 LAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY----EWYLDLRKYGSVPHS 400
+ A Y E+ ++ D ++ ++++KE+ M ++ E ++ +YG P +
Sbjct: 503 IIARYEVANAYTEL---NDPFDQKERFLEQLKEKQMGDEEAMDMDEDFIRALEYGMPPTA 559
Query: 401 GFGLGVERLVAWVLKLDHIRWATLFPR 427
G G+G++RLV + D IR LFP+
Sbjct: 560 GEGIGIDRLVMILANTDSIREVILFPQ 586
>pir||G71451 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus horikoshii
>gi|3256659|dbj|BAA29342.1| (AP000001) 294aa long
hypothetical asparaginyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 294
Score = 110 bits (272), Expect = 4e-23
Identities = 85/288 (29%), Positives = 144/288 (49%), Gaps = 39/288 (13%)
Query: 147 EWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAAI-FGLEKVWS 205
+WLL + P+ A EG L +++ + K L+ S L+ + AI GL+K++
Sbjct: 35 KWLLPVMLSPITDPLWPDPAEEGVKPL-EVEVYGKKMRLTHSMILHKQLAIAMGLKKIFV 93
Query: 206 LTPSFRAEKSRTR---RHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEI 262
L+P+ R E +R R +H EF + E + DI+ + EEL+ + RK E
Sbjct: 94 LSPNIRIE-TRERDDGKHAYEFTQFDFEVEGAKMKDIISLVEELMHGL------FRKAEE 146
Query: 263 EMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWGDDMGADEERVLTQEFDRPFFV 322
RD FP+ + ++ + K + E+G D A +Q + PF+V
Sbjct: 147 WTGRD-----------FPKARH---FKVYEYKDILDEFGSDEKA------SQVMEEPFWV 186
Query: 323 YGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDP 382
P+ FY +E+ R D++ P GYGE++ G ERE Y K++++I+ G+
Sbjct: 187 INIPRE---FYDREEDGVWRNY---DLILPYGYGEVLSGGEREWEYQKIIEKIRASGLSE 240
Query: 383 KDYEWYLDLRKYGSV-PHSGFGLGVERLVAWVLKLDHIRWATLFPRTP 429
+ ++ YL++ + G + P +G G+GVERLV +++ H+ LFPR P
Sbjct: 241 ESFKPYLEIARAGKLKPSAGAGIGVERLVRFIVSAHHVSEVQLFPRIP 288
>sp|Q9RHV9|SYK_BACST LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|6681368|dbj|BAA88691.1| (AB012100) lysyl-tRNA
synthetase [Bacillus stearothermophilus]
Length = 494
Score = 109 bits (270), Expect = 6e-23
Identities = 121/459 (26%), Positives = 205/459 (44%), Gaps = 60/459 (13%)
Query: 11 KPELDGKRVKLA--GWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGR 68
K EL+ +++++A G + + +GK F I+D TG IQ + ++ VGE +E K
Sbjct: 50 KEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDL 109
Query: 69 ESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPE------NPEQASPELLLDYR 122
V V G + + G + V + + P+PE + EQ + LD
Sbjct: 110 GDIVGVRGTMFKTK--VGELSIKVSSYEFLTKALR-PLPEKYHGLKDIEQRYRQRYLDL- 165
Query: 123 HLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT----LFKLKY 178
I +P+ + +I + R +L G+ EV P++ AV GGA +
Sbjct: 166 ---IMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMM--HAVAGGAAARPFITHHNA 220
Query: 179 FDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW 237
D Y+ + +L+L+ I G LEKV+ + FR E TR H EF LEL A+ D
Sbjct: 221 LDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTR-HNPEFTMLELYEAYADFR 279
Query: 238 DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRI--------------- 282
DIMK+ E L++++ L K + DLT P + R+
Sbjct: 280 DIMKLTENLIAHIATEVLGTTKIQYGEHLVDLT------PEWRRLHMVDAIKEYVGVDFW 333
Query: 283 ---SYDEAIEILQSKGVKIE----WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMK 335
S +EA E+ + GV++ +G + E+ + + +P F+YG+P I K
Sbjct: 334 RQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPL-AK 392
Query: 336 EDPNDPR-----KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWY 388
++P+DPR ++ + E+ ++ +++ ++ +E+G D E +
Sbjct: 393 KNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKE-REQGNDEAHEMDEDF 451
Query: 389 LDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPR 427
L+ +YG P G G+GV+RLV + IR LFP+
Sbjct: 452 LEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQ 490
>pir||JC7205 lysine-tRNA ligase (AMP forming) (EC 6.1.1.6) - Bacillus
stearothermophilus
Length = 493
Score = 109 bits (270), Expect = 6e-23
Identities = 121/459 (26%), Positives = 205/459 (44%), Gaps = 60/459 (13%)
Query: 11 KPELDGKRVKLA--GWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGR 68
K EL+ +++++A G + + +GK F I+D TG IQ + ++ VGE +E K
Sbjct: 49 KEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDL 108
Query: 69 ESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPE------NPEQASPELLLDYR 122
V V G + + G + V + + P+PE + EQ + LD
Sbjct: 109 GDIVGVRGTMFKTK--VGELSIKVSSYEFLTKALR-PLPEKYHGLKDIEQRYRQRYLDL- 164
Query: 123 HLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT----LFKLKY 178
I +P+ + +I + R +L G+ EV P++ AV GGA +
Sbjct: 165 ---IMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMM--HAVAGGAAARPFITHHNA 219
Query: 179 FDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW 237
D Y+ + +L+L+ I G LEKV+ + FR E TR H EF LEL A+ D
Sbjct: 220 LDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTR-HNPEFTMLELYEAYADFR 278
Query: 238 DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRI--------------- 282
DIMK+ E L++++ L K + DLT P + R+
Sbjct: 279 DIMKLTENLIAHIATEVLGTTKIQYGEHLVDLT------PEWRRLHMVDAIKEYVGVDFW 332
Query: 283 ---SYDEAIEILQSKGVKIE----WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMK 335
S +EA E+ + GV++ +G + E+ + + +P F+YG+P I K
Sbjct: 333 RQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPL-AK 391
Query: 336 EDPNDPR-----KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWY 388
++P+DPR ++ + E+ ++ +++ ++ +E+G D E +
Sbjct: 392 KNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKE-REQGNDEAHEMDEDF 450
Query: 389 LDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPR 427
L+ +YG P G G+GV+RLV + IR LFP+
Sbjct: 451 LEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQ 489
>pir||C75215 asparaginyl-tRNA synthetase related protein PAB2356 - Pyrococcus
abyssi (strain Orsay) >gi|5457679|emb|CAB49170.1|
(AJ248283) asparaginyl-tRNA synthetase related protein
[Pyrococcus abyssi]
Length = 294
Score = 105 bits (259), Expect = 1e-21
Identities = 75/249 (30%), Positives = 123/249 (49%), Gaps = 36/249 (14%)
Query: 185 LSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTR--RHLTEFWHLELEAAWMDLWDIMK 241
L+ S L+ + AI GLEK++ L+P+ R E R RH EF L+ E + D+M+
Sbjct: 72 LTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKDVMR 131
Query: 242 VEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWG 301
+ EEL+ + ++ E +E FPR + ++ K + E+G
Sbjct: 132 LIEELIYGLFRKAEEWTGRE-----------------FPRARH---FKVYDYKDILEEFG 171
Query: 302 DDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGG 361
D A + E + PF++ P+ FY +E+ + D++ P GYGE+ G
Sbjct: 172 SDEKA------SMEMEEPFWIVNIPRE---FYDREENGVWKNY---DLILPYGYGEVSSG 219
Query: 362 SEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSV-PHSGFGLGVERLVAWVLKLDHIR 420
ERE Y+K+V +I+ G+ + YL++ + G + P +G G+GVERLV +++ HI
Sbjct: 220 GEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVGAKHIA 279
Query: 421 WATLFPRTP 429
FPR P
Sbjct: 280 EVQPFPRVP 288
>pir||D82910 aspartyl-tRNA synthetase UU286 [imported] - Ureaplasma urealyticum
>gi|6899259|gb|AAF30695.1|AE002125_6 (AE002125)
aspartyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 578
Score = 104 bits (258), Expect = 2e-21
Identities = 84/292 (28%), Positives = 137/292 (46%), Gaps = 27/292 (9%)
Query: 4 KTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETA 63
K YC I E K V L GWV ++G +F+ ++D GI+Q K+ + VF
Sbjct: 2 KVYCGYIGEEHLEKNVILNGWVKKVRKMGNLVFVDLKDRFGIVQIFATKS---DGVFNEL 58
Query: 64 KKLGRESSVIVEGIV-----KADERAPGGAEVHVEKLKVIQAVSEFP-IPENPEQASPEL 117
+L RE + VEG+V ++ G E+HV+K+ + P I E+ A+ E+
Sbjct: 59 TQLSREDVINVEGLVLLRKNPNNDLKTGRFEIHVKKILIYSKAKTPPLIIEDETDANEEI 118
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
YR+L +R I ++ + A R +L + + E PIL EG +
Sbjct: 119 RFRYRYLDLRRDVNLKIFELRSKVYQAFRNYLYSQDFIETETPILAKPTPEGARDFYVPT 178
Query: 178 YFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
K L QS Q + + + G +K + +T FR E R+ R EF +++E ++ D
Sbjct: 179 RTRKFYALPQSPQTFKQLLMVAGFQKYFQITKCFRDEDLRSDRQ-PEFTQVDIELSFADE 237
Query: 237 WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
+I + E L+ Y+ ++T+ + DLTT PF R+SY++AI
Sbjct: 238 IEIQTLIENLLKYVFKQTINV----------DLTT------PFMRMSYEQAI 273
>sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|420805|pir||S33743 aspartate--tRNA ligase (EC
6.1.1.12) - Thermus aquaticus >gi|9257069|pdb|1EFW|A
Chain A, Crystal Structure Of Aspartyl-Trna Synthetase
From Thermus Thermophilus Complexed To Trnaasp From
Escherichia Coli >gi|9257070|pdb|1EFW|B Chain B, Crystal
Structure Of Aspartyl-Trna Synthetase From Thermus
Thermophilus Complexed To Trnaasp From Escherichia Coli
>gi|396501|emb|CAA50282.1| (X70943) aspartyl-tRNA
synthetase [Thermus thermophilus]
Length = 580
Score = 104 bits (257), Expect = 2e-21
Identities = 86/311 (27%), Positives = 151/311 (47%), Gaps = 35/311 (11%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
Y ++ G+ V L GWV +G IFL +RD G++Q V + TA++
Sbjct: 6 YAGSLRETHVGEEVVLEGWVNRRRDLGGLIFLDLRDREGLVQLVAHP---ASPAYATAER 62
Query: 66 LGRESSVIVEGIVKADER-----APGGAEVHVEKLKVIQAVSEFPIP-------ENPEQA 113
+ E V +G+V+ A G EV + L+V+ P P E ++A
Sbjct: 63 VRPEWVVRAKGLVRLRPEPNPRLATGRVEVELSALEVLAEAKTPPFPVDAGWRGEEEKEA 122
Query: 114 SPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT- 172
S EL L YR+L +R ++ +R++ +I A ++L REG+ +V P L EG
Sbjct: 123 SEELRLKYRYLDLRRRRMQENLRLRHRVIKAIWDFLDREGFVQVETPFLTKSTPEGARDF 182
Query: 173 LFKLKYFDKVAY-LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELE 230
L ++ + Y L QS QL+ + + GL++ + + FR E R R +F L+LE
Sbjct: 183 LVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRDEDLRADRQ-PDFTQLDLE 241
Query: 231 AAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEI 290
+++++ D++++ E L++++ + L + E+ + PFPR+SY+EA+E
Sbjct: 242 MSFVEVEDVLELNERLMAHVFREALGV---ELPL-------------PFPRLSYEEAMER 285
Query: 291 LQSKGVKIEWG 301
S + +G
Sbjct: 286 YGSDKPDLRFG 296
>sp|Q9KGG4|SYK_BACHD LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|10172710|dbj|BAB03817.1| (AP001507) lysyl-tRNA
synthetase [Bacillus halodurans]
Length = 501
Score = 103 bits (254), Expect = 5e-21
Identities = 123/476 (25%), Positives = 215/476 (44%), Gaps = 76/476 (15%)
Query: 2 IEKTYCQDIKPELDGK--RVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDV 59
+++ Y K EL+ + V LAG V + GK F I+D TG IQ + K+ VG+
Sbjct: 42 MKEKYDAKSKEELEEETHEVVLAGRVMTKRGKGKAGFAHIQDLTGQIQIYVRKDAVGDKS 101
Query: 60 FETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPE------NPEQA 113
++ + V V+G+ A + G V V+ +++ S P+P+ + EQ
Sbjct: 102 YDLFTSIDIGDIVGVKGV--AFKTKVGELSVKVQDFQLLTK-SLRPLPDKYHGLKDVEQR 158
Query: 114 SPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATL 173
+ LD I +P+V ++ ++ + R +L G+ EV P + ++ GGA+
Sbjct: 159 YRQRYLDL----IVNPEVRDTFVLRSKILQSMRRYLDDRGYLEVETPTM--HSIPGGASA 212
Query: 174 FKL----KYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLE 228
D Y+ + +L+L+ I G +EKV+ + FR E TR H EF +E
Sbjct: 213 RPFVTHHNALDMTLYMRIAIELHLKRLIVGGMEKVYEIGRVFRNEGVSTR-HNPEFTMIE 271
Query: 229 LEAAWMDLWDIMKVEEELVSYM---VQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYD 285
L A+ D DIM++ E L++++ V T + E E+ N EP + R+
Sbjct: 272 LYEAYADYNDIMELTELLIAHIAKDVLGTTTITYGEHEV---------NLEPKWRRVHMV 322
Query: 286 EAIEILQSKGVKIEWGDDMGADEERVLTQEFD--------------------------RP 319
EAI+ + +++ ++M +E R L +E + +P
Sbjct: 323 EAIK----EETGVDFWNEMSDEEARALAKEHNVPVKETMTYGHVVNEFFEHFVEEKLIQP 378
Query: 320 FFVYGYPKHIKAFYMKEDPNDPR-----KVLAADMLAPEGYGEIIGGSEREDNYDK-LVQ 373
FVYG+P I K++P+DPR ++ + E+ ++ +++ LV+
Sbjct: 379 TFVYGHPVAISPL-AKKNPDDPRFTDRFELFIVGREHANAFSELNDPIDQRHRFEQQLVE 437
Query: 374 RIKEEGMDPKDY--EWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPR 427
R E+G D E +++ +YG P G G+G++RLV + IR LFP+
Sbjct: 438 R--EQGDDEAHMMDEDFVESLEYGMPPTGGLGIGIDRLVMLLTNSPSIRDVLLFPQ 491
>emb|CAC08476.1| (AL392189) aspartyl-tRNA synthetase [Streptomyces coelicolor]
Length = 587
Score = 102 bits (252), Expect = 8e-21
Identities = 90/352 (25%), Positives = 169/352 (47%), Gaps = 42/352 (11%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKL 66
C +++ G V+L+GW+++ +G +F+ +RD GI Q V G + +E KL
Sbjct: 9 CGELRSSDVGTDVRLSGWLHNRRDLGGILFIDLRDHYGITQLVARP---GTEAYEALDKL 65
Query: 67 GRESSVIVEGIVK---ADERAP----GGAEVHVEKLKVIQAVSEFPIPENPEQA-SPELL 118
+ES+V V+G V AD P G EV V +++++ A P N E + E
Sbjct: 66 TKESTVRVDGKVVSRGADNINPDLPTGEVEVEVGEVELLGAAQPLPFTINTEDGVNEERR 125
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--KL 176
L+YR L +R ++ + ++ ++I + R ++ G++E+ PIL + EG
Sbjct: 126 LEYRFLDLRRERMHRNIMLRTSVISSIRSKMVALGFNEMATPILTATSPEGARDFVVPSR 185
Query: 177 KYFDKVAYLSQSAQLYLEAA-IFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
+ + L Q+ Q + + I G ++ + + P FR E +R R EF+ L++E ++++
Sbjct: 186 LHAGRFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVEMSFVE 245
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKG 295
D+ + E+L++ E+F ++ ++ PFPRI + EA+
Sbjct: 246 QEDVFRPIEQLMT--------------ELF-EEFGNGRHVTSPFPRIPFREAM------- 283
Query: 296 VKIEWGD---DMGADEERV-LTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRK 343
+++G D+ A E V +T F+ F KH++A + + PR+
Sbjct: 284 --LKYGSDKPDLRAQLELVDITDVFEGSEFKAFAGKHVRALPVPDVSGQPRR 333
>sp|Q9PEB6|SYK_XYLFA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|11271299|pir||E82721 lysyl-tRNA synthetase XF1112
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9106069|gb|AAF83922.1|AE003947_2 (AE003947)
lysyl-tRNA synthetase [Xylella fastidiosa]
Length = 506
Score = 101 bits (249), Expect = 2e-20
Identities = 118/452 (26%), Positives = 191/452 (42%), Gaps = 53/452 (11%)
Query: 13 ELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSV 72
E G RV++AG + + +GK F I+D +G IQ +I NV+GED + K L +
Sbjct: 64 EASGDRVRMAGRLMAKRLMGKASFAQIQDESGRIQLLIQSNVLGEDSYAAFKVLDVGDII 123
Query: 73 IVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPE------NPEQASPELLLDYRHLHI 126
VEG + +V+V +L + +A+ P+P+ + EQ + +D I
Sbjct: 124 AVEGGLTRTRTGELSVKVNVLRL-LTKALR--PLPDKWHGLTDVEQRYRQRYVDL----I 176
Query: 127 RSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAY 184
+P+ I + +I A R WL + EV P++ + G + D Y
Sbjct: 177 VTPESREIFIKRSKIIRALRTWLDARLFLEVETPMMHYIPGGAAAKPFVTYHNALDLELY 236
Query: 185 LSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVE 243
L + +LYL+ + GLE+V+ + +FR E T RH EF LEL A+ ++M +
Sbjct: 237 LRVAPELYLKRLVVGGLERVYEINRNFRNEGVST-RHNPEFTMLELYEAYSTYHEVMDLA 295
Query: 244 EELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI--------------- 288
E ++ Q L + + + DL P F R DEA+
Sbjct: 296 ETMIRDTAQSVLGTTQVIWDGAQIDL------GPIFRRWRMDEAVCHHNPEISVAECTDR 349
Query: 289 --EILQSKGVKIE------WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKED--- 337
+L + +KI+ WG + + E + +P F+ +P I + D
Sbjct: 350 DALLLHCERLKIKVKSSYGWGRLLLSIFEATVEHTLIQPTFITDHPVEISPLARESDIEP 409
Query: 338 -PNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWYLDLRKY 394
D ++ G+ E+ E+ + K V+ KE G D Y Y+ +Y
Sbjct: 410 GYTDRFELFINGKEIANGFSELNDPEEQAMRFQKQVE-AKEGGDDEAMYYDADYIRALEY 468
Query: 395 GSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
G P G G+GV+RLV + IR LFP
Sbjct: 469 GMAPTGGLGIGVDRLVMLLTGSTSIRDVLLFP 500
>sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437585|pir||D70445 aspartate--tRNA ligase (EC
6.1.1.12) - Aquifex aeolicus >gi|2984003|gb|AAC07548.1|
(AE000750) aspartyl-tRNA synthetase [Aquifex aeolicus]
Length = 603
Score = 100 bits (247), Expect = 3e-20
Identities = 81/295 (27%), Positives = 128/295 (42%), Gaps = 29/295 (9%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC ++ E GK VKLAGWV+ G IF+ +RD GI+Q V+ + + +E A K
Sbjct: 13 YCGEVSEEDIGKEVKLAGWVHRKRHHGGVIFIDLRDREGIVQVVVEEK-TNPEAYEVADK 71
Query: 66 LGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIP-ENPEQASPEL 117
L E + V G V+ + G EV +++ V P P E S E
Sbjct: 72 LKSEYVIGVVGKVRKRPEGTENPKLKTGYVEVVADRILVFNTSEALPFPVEEETHVSEET 131
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--K 175
L YR++ +R + + + + R + +EG+ E+ P L EG
Sbjct: 132 KLKYRYIDLRRESMKNNLIFRHRVYQITRNFFTKEGFIEIETPFLTKSTPEGARDFLVPS 191
Query: 176 LKYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
+ K L QS QL+ + I G ++ + + FR E R R EF ++ E +++
Sbjct: 192 RLHPGKFYALPQSPQLFKQILMIAGFDRYFQIVKCFRDEDLRADRQ-PEFTQIDYEMSFV 250
Query: 235 DLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
++M V E L++ + + L + K PF RISY EA+E
Sbjct: 251 SEEEVMDVAERLIATLFKELLGVELK----------------TPFERISYREAME 289
>sp|Q9PR83|SYK_UREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|11271293|pir||G82937 lysyl-tRNA synthetase UU062
[imported] - Ureaplasma urealyticum
>gi|6899012|gb|AAF30467.1|AE002106_1 (AE002106)
lysyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 493
Score = 99.8 bits (245), Expect = 5e-20
Identities = 116/457 (25%), Positives = 207/457 (44%), Gaps = 50/457 (10%)
Query: 4 KTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETA 63
K + ++ +D +++ LAG + ++ F I+D + +Q I K V +VF T
Sbjct: 46 KNFSKEELHNMDLEKLTLAGRLIGI----RQTFGIIQDFSAKLQIYINKKNVAPEVFSTF 101
Query: 64 KKLGRESSVIVEGIV---KADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQ-ASPELLL 119
K L + +EG+ +DE ++V ++++ A S +PE E+
Sbjct: 102 KSLDIGDIIELEGVAMKTNSDE-----ITLNVTNIRLV-AKSLKVLPEKYHGLVDEEIKA 155
Query: 120 DYRHLHIRSPKVSAIMRVKETLIMAA-REWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
R+L + + +K +LI+ R WL +G+ EV P+L A F +
Sbjct: 156 RQRYLDLIVNDETKNTFIKRSLIIREMRNWLDNKGFFEVETPVLQDILSGAAARPFITHH 215
Query: 179 --FDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
+K YL + ++ L+ I G EKV+ + FR E H EF +EL A++D
Sbjct: 216 NTLNKEYYLRIATEIALKKCIIGGFEKVYEIGRIFRNE-GMDSTHNPEFTSVELYIAYVD 274
Query: 236 LWDIMKVEEELVSYMVQR-----------TLELRKKEIEMFRDDLTTLKNTEPPFPRISY 284
LW IM++ E+L+ ++ + +++L K + DL F S
Sbjct: 275 LWYIMQLTEDLIRHIATKLNLLNPTFRGFSIDLNKPFKKAHMVDLINEYVGVNFFEVKSD 334
Query: 285 DEAIEILQSKGVKI-----EWGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPN 339
++AIE+ + VK+ +G + A E + ++ P FVYG+P + K++ +
Sbjct: 335 EQAIELAKKHHVKLLDHQKNFGHIVNAFFETFVEEKLVEPTFVYGHPLQVSPL-TKKNQS 393
Query: 340 DPRKVLAADMLAPE-----GYGEIIGGSEREDNYDKLVQRIKEEGM-----DPKDYEWYL 389
DPR V ++ + Y EI ++ D Y++ + +++E + D E ++
Sbjct: 394 DPRFVDRFELFICQKEFANAYSEI---NDPIDQYERFIAQLEEAKLGNDEASELDME-FI 449
Query: 390 DLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
+ +YG P G G+GV+RLV + D IR LFP
Sbjct: 450 EALEYGMPPTGGLGIGVDRLVMLLTSNDSIRNVLLFP 486
>sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|567884|gb|AAA53114.1| (L36472) lysyl-tRNA synthetase
[Staphylococcus aureus]
Length = 495
Score = 99.5 bits (244), Expect = 7e-20
Identities = 111/448 (24%), Positives = 196/448 (42%), Gaps = 41/448 (9%)
Query: 10 IKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRE 69
++ E D V +AG + + GK F ++D G IQ + K+ VG+D F+ K
Sbjct: 53 VEKEADS-HVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADLG 111
Query: 70 SSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIP------ENPEQASPELLLDYRH 123
V VEG++ + G V +K ++ S P+P ++ EQ + LD
Sbjct: 112 DIVGVEGVM--FKTNTGELSVKAKKFTLL-TKSLRPLPDKFHGLQDIEQRYRQRYLDL-- 166
Query: 124 LHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDK 181
I + + + +I R +L +G+ EV P++ + G + D
Sbjct: 167 --ITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDA 224
Query: 182 VAYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM 240
Y+ + +L+L+ I GLEKV+ + FR E T RH EF +EL A+ D DIM
Sbjct: 225 TLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVST-RHNPEFTMIELYEAYADYHDIM 283
Query: 241 KVEEELVSYMVQRTLELRKKEIEMFRDDLTTL-----------KNTEPPFPRISYDEAIE 289
+ E +V ++ L K + DL + + T F + DE +
Sbjct: 284 DLTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEERK 343
Query: 290 IL-QSKGVKI----EWGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPR-- 342
L + G++I ++G + E+ + + +P F+YG+P I K++P DPR
Sbjct: 344 ALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPL-AKKNPEDPRFT 402
Query: 343 ---KVLAADMLAPEGYGEIIGGSEREDNYD-KLVQRIKEEGMDPKDYEWYLDLRKYGSVP 398
++ + E+ +++ ++ +LV++ + + E Y++ +YG P
Sbjct: 403 DRFELFIVGREHANRFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEYGMPP 462
Query: 399 HSGFGLGVERLVAWVLKLDHIRWATLFP 426
G G+G++RLV + IR LFP
Sbjct: 463 TGGLGIGIDRLVMLLTDSPSIRDVLLFP 490
>sp|Q9X231|SYK_THEMA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437571|pir||C72221 lysine--tRNA ligase (EC 6.1.1.6)
- Thermotoga maritima (strain MSB8)
>gi|4982282|gb|AAD36772.1|AE001810_11 (AE001810)
lysyl-tRNA synthetase [Thermotoga maritima]
Length = 502
Score = 99.5 bits (244), Expect = 7e-20
Identities = 121/451 (26%), Positives = 201/451 (43%), Gaps = 56/451 (12%)
Query: 14 LDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGE---DVFETAKKLGRES 70
L+ +++ AG V S GK F ++D TG IQ I + VG+ D+F+ K+G
Sbjct: 50 LESEKLSFAGRVMSIRHHGKTAFFHMKDDTGRIQAYIKADSVGKEKMDLFKRHVKIG--D 107
Query: 71 SVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQ-ASPELLLDYRHLHIRSP 129
V V G + G ++V++ ++ P+PE E++ R+L +
Sbjct: 108 FVGVRGF--PFKSKTGELTIYVQEYTLLSKALR-PLPEKWHGIKDKEIIYRQRYLEL-IV 163
Query: 130 KVSAIMRVKETL--IMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYL 185
AI R K+ + RE+L G+ EV PIL VTG E + L FD YL
Sbjct: 164 NDEAIERFKKRFKAVRVIREFLNSRGFIEVETPILHYVTGGAEARPFVTHLNVFDIDMYL 223
Query: 186 SQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEE 244
+ +LYL+ I G EK++ + +FR E + +H EF +E+ A+ D D+M + E
Sbjct: 224 RIAPELYLKRLIVGGFEKIYEIGKNFRNE-GISYKHSPEFTSIEIYQAYADYNDMMDLTE 282
Query: 245 ELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISY----------------DEA- 287
EL+ +V+RT K + D T PP+ R+ DE
Sbjct: 283 ELIVEVVKRTCGTLKISYQGKEIDFT------PPWKRVRMRDFLKEKLGVDILEDPDEVL 336
Query: 288 IEILQSKGVKIEWGDDMGADEE--RVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVL 345
++ L+ GV++E + ++ ++ +E P F+ +P I K DPR
Sbjct: 337 LKKLEEHGVELEIKNRAHLIDKLRDLVEEELVNPTFIIDHPVVISPL-AKRHREDPRLTE 395
Query: 346 AADMLAPEGYGEIIGGSERE-----DNYDKLVQ--RIKEEGMDPKDYEWYLDL---RKYG 395
+++ +G I + E D Y + ++ +++EEG D + + LD +YG
Sbjct: 396 RFELII---FGREIANAFSELNDPVDQYQRFLEQAKMREEG-DEEAHMMDLDFVRALEYG 451
Query: 396 SVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
P G G+G++RL ++ IR FP
Sbjct: 452 MPPTGGLGIGLDRLFMFITDSPTIRDVIPFP 482
>sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2127132|pir||S66111 lysine--tRNA ligase (EC 6.1.1.6)
lysS - Bacillus subtilis >gi|467470|dbj|BAA05316.1|
(D26185) lysyl-tRNA thynthetase [Bacillus subtilis]
>gi|2632349|emb|CAB11858.1| (Z99104) lysyl-tRNA
synthetase [Bacillus subtilis]
Length = 499
Score = 97.9 bits (240), Expect = 2e-19
Identities = 114/461 (24%), Positives = 204/461 (43%), Gaps = 49/461 (10%)
Query: 8 QDI-KPELDGKRVK--LAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAK 64
QD+ K EL+ K ++ +AG + + GK F ++D G IQ + K+ VG+D +E K
Sbjct: 51 QDLTKEELEEKAIEVTIAGRMMTKRGKGKAGFAHLQDLEGQIQIYVRKDSVGDDQYEIFK 110
Query: 65 KLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPE------NPEQASPELL 118
+ V G K + G V +++ P+P+ + EQ +
Sbjct: 111 SSDLGDLIGVTG--KVFKTNVGELSVKATSFELLTKALR-PLPDKYHGLKDVEQRYRQRY 167
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT----LF 174
LD I +P + +I A R +L G+ EV P + ++ GGA+ +
Sbjct: 168 LDL----IVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTM--HSIPGGASARPFIT 221
Query: 175 KLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAW 233
D Y+ + +L+L+ I G LEKV+ + FR E TR H EF +EL A+
Sbjct: 222 HHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTR-HNPEFTMIELYEAY 280
Query: 234 MDLWDIMKVEEELVSYMVQR-----TLELRKKEIEMFRD-------DLTTLKNTEPPFPR 281
D DIM + E LV+++ Q T++ +++I++ + D +
Sbjct: 281 ADYKDIMSLTENLVAHIAQEVLGTTTIQYGEEQIDLKPEWKRIHMVDAVKEATGVDFWEE 340
Query: 282 ISYDEAIEILQSKGVKIEWGDDMGADEERVLTQEFD----RPFFVYGYPKHIKAFYMKED 337
++ ++A E + V+I+ +G Q+ + +P F+YG+P I K++
Sbjct: 341 VTVEQAREYAKEHEVEIKDSMTVGHIINEFFEQKIEETLIQPTFIYGHPVEISPL-AKKN 399
Query: 338 PNDPR-----KVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWYLD 390
P DPR ++ + E+ ++ + ++ ++ +E G D E +++
Sbjct: 400 PEDPRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLKE-REAGNDEAHLMDEDFVE 458
Query: 391 LRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPAR 431
+YG P G G+G++RLV + IR LFP+ R
Sbjct: 459 ALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPQMRQR 499
>pir||H82627 aspartyl-tRNA synthetase XF1856 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106945|gb|AAF84662.1|AE004007_1
(AE004007) aspartyl-tRNA synthetase [Xylella fastidiosa]
Length = 589
Score = 97.1 bits (238), Expect = 3e-19
Identities = 82/294 (27%), Positives = 135/294 (45%), Gaps = 29/294 (9%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGE---DVFET 62
+C I L G V LAGW +G F+ +RD GI+Q + + + ++F+
Sbjct: 5 FCGLIDETLIGHTVTLAGWTDVARNLGGVCFIDLRDHEGIVQVTVDSRAIDQNNSELFKV 64
Query: 63 AKKLGRESSVIVEGIVKA-----DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPEL 117
A L E + VEG+V A D+ G EV K+K++ + P + E ++
Sbjct: 65 ASGLSYEDVLQVEGVVCARHAVNDKIKTGKVEVIATKIKILNKAAPLPFHAH-ENPGEDI 123
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT-LFKL 176
L YR+L +R P++ + R + L+ A R L G+ ++ PIL EG L
Sbjct: 124 RLKYRYLDLRRPEMQRMQRTRIKLVQALRRHLDMHGFQDIETPILTKATPEGARDFLVPA 183
Query: 177 KYFDKVAY-LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
+ Y L QS QL+ + + G ++ + + FR E R R L EF L++E A++
Sbjct: 184 RMHPGEFYALPQSPQLFKQILMVAGFDRYYQIARCFRDEALRADRQL-EFTQLDMEFAFV 242
Query: 235 DLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
D+ ++ V M++R KE+ D T FPR+++ EA+
Sbjct: 243 SERDV----QDFVEEMIRRVF----KEVAGIELDTT--------FPRMTWTEAM 280
>pir||I40523 asparagine--tRNA ligase (EC 6.1.1.22) - Bacillus subtilis
(fragment) >gi|533097|gb|AAA80003.1| (U11289)
asparaginyl-tRNA synthetase [Bacillus subtilis]
Length = 77
Score = 96.3 bits (236), Expect = 6e-19
Identities = 44/77 (57%), Positives = 54/77 (69%)
Query: 358 IIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLD 417
IIGGSER + + L R+KE G+D Y+WY +LRKYGSVPHSGFGLG+ER VAW+
Sbjct: 1 IIGGSERIHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAP 60
Query: 418 HIRWATLFPRTPARIYP 434
H+R FPR R+YP
Sbjct: 61 HVRETIPFPRLLNRLYP 77
>pir||F82234 aspartyl-tRNA synthetase VC1166 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655641|gb|AAF94325.1| (AE004196)
aspartyl-tRNA synthetase [Vibrio cholerae]
Length = 591
Score = 94.4 bits (231), Expect = 2e-18
Identities = 78/293 (26%), Positives = 134/293 (45%), Gaps = 31/293 (10%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC + L G+ V+L GWV +G IF+ +RD GI+Q V+ ++ DVF A +
Sbjct: 5 YCGHLNKSLVGQTVELCGWVNRRRDLGGLIFIDMRDREGIVQVVVDPDMA--DVFAVANQ 62
Query: 66 LGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
L E + + G V+A E A G E+ L++I P+ N ++ S E
Sbjct: 63 LRSEFCIKLTGEVRARPESQVNKEMATGEVELLARSLEIINRSDVLPLDFN-QKNSEEQR 121
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
L YR+L +R P++S ++++ R +L G+ ++ P+L EG
Sbjct: 122 LKYRYLDLRRPEMSDRIKLRAKASSFVRRFLDTHGFLDIETPVLTKATPEGARDYLVPSR 181
Query: 179 FDKVAY--LSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
K ++ L QS QL+ + + G ++ + + FR E R R EF +++E ++M
Sbjct: 182 VHKGSFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDIETSFMT 240
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
+ V E+++ R+ +E+ DL FP + Y EA+
Sbjct: 241 AEQVRAVTEKMI----------REMWLELLNVDL-------GDFPIMPYSEAM 276
>sp|O87821|SYK_RHIME LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|3582260|gb|AAC35210.1| (M27221) lysyl-tRNA
synthetase [Sinorhizobium meliloti]
Length = 498
Score = 94.0 bits (230), Expect = 3e-18
Identities = 118/454 (25%), Positives = 195/454 (41%), Gaps = 52/454 (11%)
Query: 10 IKPELD-GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGR 68
++P+ + G+ V +AG V+S+ G +F+ + D++G IQ K+ E+ +
Sbjct: 53 LEPDTESGETVTVAGRVFSSRNSG--MFMDLHDASGKIQIFSHKDTAPEEARALLPMIDL 110
Query: 69 ESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQ-ASPELLLDYRHLHIR 127
+ V G V+ +R G V+ +++ ++ S P+PE A E R+L I
Sbjct: 111 GDIIGVTGEVRRTKR--GELTVNAKEITML-CKSLLPMPEKYHGLADIETRYRKRYLDIM 167
Query: 128 SPKVSAI-MRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVA--- 183
+ S + + + ++ + R +L EG+ EV P+L + GGAT K
Sbjct: 168 VNEESKLRFQQRSRIVSSLRRFLEDEGFMEVETPMLQP--IYGGATAEPFKTHHNTLKLD 225
Query: 184 -YLSQSAQLYLEAAIFG--LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIM 240
YL +A+LYL A + +KV+ + +FR E TR H EF +E A+ D D+M
Sbjct: 226 MYLRIAAELYLNAILVSGLTDKVFEINRNFRNEGVSTR-HNPEFTMMECYWAYADYEDVM 284
Query: 241 KVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISY---------------- 284
+ E + + L + K F D + K PFPR+S
Sbjct: 285 GLVERMFETLA---LAVHGKTEFEFGDKQLSFKG---PFPRVSMPAASRTRPESISLPLK 338
Query: 285 --DEAIEILQSKGVKIE----WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDP 338
+EA + + GV+IE WG+ + E + +P V +PK I F KE P
Sbjct: 339 SDEEARQAARDAGVEIEKDATWGEVLAFLFEEKVEATLIQPAHVIHFPKDISPF-AKEVP 397
Query: 339 NDPRKVLAADMLAP-----EGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY-EWYLDLR 392
+PR V + + E+ E+ + +++ G K E +LD
Sbjct: 398 GEPRLVERFETYCNGWEIGNAFSELNDPVEQRARMVEQMEQAHARGEKEKTLDEDFLDAM 457
Query: 393 KYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
G P G G+GV+RL+ + IR LFP
Sbjct: 458 DQGMPPAGGLGIGVDRLIMLLTNSPSIRDIILFP 491
>pir||D75406 aspartyl-tRNA synthetase, discriminating - Deinococcus radiodurans
(strain R1) >gi|6459100|gb|AAF10918.1|AE001981_3
(AE001981) aspartyl-tRNA synthetase, discriminating
[Deinococcus radiodurans]
Length = 577
Score = 93.2 bits (228), Expect = 5e-18
Identities = 74/280 (26%), Positives = 135/280 (47%), Gaps = 29/280 (10%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGIV 78
V L GWV +G IFL +RD +G +Q + + F A +L E +EG
Sbjct: 20 VTLQGWVSRRRDLGGLIFLELRDRSGTVQVQVEPD---SPAFAEADRLRAEYVAEIEGTF 76
Query: 79 --KADERAPGGA---EVHVEKLKVIQAVSEFPIP-ENPEQASPELLLDYRHLHIRSPKVS 132
+ + + GG EV ++KV+ A P + E + ++ L YR+L +R P++
Sbjct: 77 QPRPESQRKGGLADFEVIASRVKVLNAAKTPPFELDKGESVAEDIRLKYRYLDLRRPEMQ 136
Query: 133 AIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAY--LSQSAQ 190
+ ++ + A E+L EG+ +V P+L EG + + L QS Q
Sbjct: 137 RALMLRSKAVTAVTEFLDAEGFIQVETPMLTKSTPEGARDFLVPSRLNPGEFYALPQSPQ 196
Query: 191 LYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSY 249
L+ + I G ++ + L FR E R R +F L++E ++++ D+++V+E L+++
Sbjct: 197 LFKQLLMIAGFDRYYQLARCFRDEDLRADRQ-PDFTQLDMEMSFVEQDDVLEVQERLLAH 255
Query: 250 MVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
+ +R L++ E+ + PFPR+SY +A++
Sbjct: 256 VFRRVLDV---ELPL-------------PFPRMSYFDAMD 279
>sp|Q9X1F4|SYD_THEMA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437606|pir||F72252 aspartate--tRNA ligase (EC
6.1.1.12) - Thermotoga maritima (strain MSB8)
>gi|4982006|gb|AAD36510.1|AE001796_2 (AE001796)
aspartyl-tRNA synthetase [Thermotoga maritima]
Length = 579
Score = 92.1 bits (225), Expect = 1e-17
Identities = 78/300 (26%), Positives = 136/300 (45%), Gaps = 33/300 (11%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M+ C +++ +GK+VKL GWV +G F+ +RD G Q V V + +
Sbjct: 1 MLRTHTCGELRATDEGKKVKLCGWVDRIRDLGGVRFIDLRDRYGETQIVCD---VNSEAY 57
Query: 61 ETAKKLGRESSVIVEGIVKADERA-------PGGAEVHVEKLKVIQAVSEFPIPENP-EQ 112
+L RES V+VEG V+ G EV E+++++ P+P P E
Sbjct: 58 SVVDELTRESVVLVEGTVRKRPEGTENPNIETGEIEVVAERIEILSLAD--PLPFYPGET 115
Query: 113 ASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT 172
E+ L YR++ +RS ++ + ++ + R++ G+ E+ P L EG
Sbjct: 116 PKEEMRLKYRYIDLRSERMKRNIILRYRISKIIRDYFDELGFLEIETPFLTRSTPEGARD 175
Query: 173 LFKLKYF--DKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLEL 229
K L QS QL+ + I G ++ + + FR E R R EF +++
Sbjct: 176 FLVPSRLRPGKFYALPQSPQLFKQILMISGFDRYFQIVRCFRDEDLRADRQ-PEFTQVDV 234
Query: 230 EAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
E +++D+ D++ V E +VS + + + + + + PF RI YD+A+E
Sbjct: 235 EMSFVDVEDVLNVSEGMVSRVFKESSGI----------------DLKVPFDRIPYDDAME 278
>sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437588|pir||C70724 aspartate--tRNA ligase (EC
6.1.1.12) - Mycobacterium tuberculosis (strain H37RV)
>gi|1478240|emb|CAB01271.1| (Z77724) aspS [Mycobacterium
tuberculosis]
Length = 596
Score = 91.7 bits (224), Expect = 2e-17
Identities = 94/344 (27%), Positives = 152/344 (43%), Gaps = 43/344 (12%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
G++V LAGWV G IF+ +RD++GI Q V+ ++ +V A +L E V V
Sbjct: 18 GQQVTLAGWVARRRDHGGVIFIDLRDASGIAQ-VVFRDPQDTEVLAQAHRLRAEFCVSVA 76
Query: 76 GIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRS 128
G+V+ E A G EV+ L V+ + P + E A EL L YR+L +R
Sbjct: 77 GVVEIRPEGNANPEIATGEIEVNATSLTVLGECAPLPF-QLDEPAGEELRLKYRYLDLRR 135
Query: 129 PKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAY--LS 186
+A +R++ + AAR L R + E+ P + EG ++ L
Sbjct: 136 DDPAAAIRLRSRVNAAARAVLARHDFVEIETPTITRSTPEGARDFLVPARLHPGSFYALP 195
Query: 187 QSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEE 245
QS QL+ + + G+E+ + + +R E R R EF L++E +++D DI+ + EE
Sbjct: 196 QSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQ-PEFTQLDMEMSFVDAEDIIAISEE 254
Query: 246 LVSYMVQRTLELRKKEIEMFRDDLTTL--KNTEPPFPRISYDEAIEILQSKGVKIEWGDD 303
+++ +L L P PRI Y EA+ + + +G
Sbjct: 255 VLT-------------------ELWALIGYRIPTPIPRIGYAEAMRRFGTDKPDLRFG-- 293
Query: 304 MGADEERVLTQEF--DRPFFVYGYPKHIKAFYMKEDPNDPRKVL 345
E V +F D F V+ P ++ A M + PR+ L
Sbjct: 294 ----LELVECTDFFSDTTFRVFQAP-YVGAVVMPGGASQPRRTL 332
>sp|O83950|SYD_TREPA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437587|pir||A71256 aspartate--tRNA ligase (EC
6.1.1.12) - syphilis spirochete
>gi|3323310|gb|AAC65942.1| (AE001266) aspartyl-tRNA
synthetase (aspS) [Treponema pallidum]
Length = 602
Score = 91.3 bits (223), Expect = 2e-17
Identities = 73/296 (24%), Positives = 141/296 (46%), Gaps = 33/296 (11%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKL 66
C +++ G V L GWV+ G F +RD +GI+Q ++++ ++ T ++
Sbjct: 23 CGELRRCHVGTVVVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIVSQEE-NASLWSTVNRI 81
Query: 67 GRESSVIVEGIVKADERAP---------GGAEVHVEKLKVIQAVSEFPIP-ENPEQASPE 116
E + VEG+V+ ER P G EVH L V+ + P ++ A +
Sbjct: 82 RLECCLAVEGVVR--ERPPSMINRALHTGEVEVHARTLYVLSENAVLPFRVDDVVHAHED 139
Query: 117 LLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKL 176
+ L YR+L +RS ++ + ++ + +A R++L +G+ E+ P + EG
Sbjct: 140 IRLKYRYLDLRSQRMQERIALRSRVALAIRQFLSMKGFIEIETPTFICSTPEGARDFVVP 199
Query: 177 KYF--DKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAW 233
+ L QS QLY + + G ++ + L +R E +R R EF ++LE ++
Sbjct: 200 SRVCPGRFYALPQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQ-PEFTQIDLEMSF 258
Query: 234 MDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
+ D+M+V E+++ Y+ + ++ + E+ F FPR++Y +A++
Sbjct: 259 VSRDDVMRVNEDMLRYVFRTSIGV---ELPTF-------------FPRLTYAQALD 298
>pir||E83524 aspartyl-tRNA synthetase PA0963 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946870|gb|AAG04352.1|AE004530_5
(AE004530) aspartyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 591
Score = 91.3 bits (223), Expect = 2e-17
Identities = 72/272 (26%), Positives = 123/272 (44%), Gaps = 14/272 (5%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M+ YC + LDG+ V L GWV+ G IFL +RD G+ Q V + + F
Sbjct: 1 MMRSHYCGQLNESLDGQEVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDPD--RAETF 58
Query: 61 ETAKKLGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIP-ENPEQ 112
A ++ E V + G V+ A G EV +L+V+ P P +
Sbjct: 59 AKADRVRSEFVVKITGKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYSD 118
Query: 113 ASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT 172
E L YR + +R P+++A ++++ + + R +L G+ +V PIL EG
Sbjct: 119 VGEETRLRYRFIDLRRPEMAAKLKLRARITSSIRRYLDDNGFLDVETPILGRPTPEGARD 178
Query: 173 LF--KLKYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLEL 229
Y L QS QL+ + + G ++ + + FR E R R EF +++
Sbjct: 179 YLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQ-PEFTQIDI 237
Query: 230 EAAWMDLWDIMKVEEELVSYMVQRTLELRKKE 261
E +++D DI+ + E++V + + L++ E
Sbjct: 238 ETSFLDESDIIGITEKMVRQLFKEVLDVEFDE 269
>sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS) (ANTIGEN
T5) >gi|541455|pir||S42047 aspartate--tRNA ligase (EC
6.1.1.12) - Mycobacterium leprae
>gi|581332|emb|CAA54735.1| (X77655) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3136016|emb|CAA19094.1| (AL023591) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3335328|gb|AAC27132.1|S82268_1 (S82268)
aspartyl-tRNA synthetase [Mycobacterium leprae]
Length = 589
Score = 90.9 bits (222), Expect = 3e-17
Identities = 96/342 (28%), Positives = 151/342 (44%), Gaps = 42/342 (12%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
G++V LAGWV G IF+ +RDS+GI Q V + DV A +L E + V
Sbjct: 16 GQQVTLAGWVSRRRDHGGVIFIDLRDSSGITQAVFRE----PDVLAQAHRLRAEFCIAVS 71
Query: 76 GIVK------ADERAP-GGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRS 128
G+V+ A+ P G EV+ L V+ + P + E A EL L YR+L +R
Sbjct: 72 GVVEIRPEGNANAEIPTGDIEVNATSLTVLGESAPLPF-QLDEPAGEELRLKYRYLDLRR 130
Query: 129 PKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT-LFKLKYFDKVAY-LS 186
+ +R++ + AR L R + E+ P + EG L + Y L
Sbjct: 131 DGPGSAIRLRSKVNATARAVLARHDFVEIETPTITRSTPEGARDFLVPARLRPGTFYALP 190
Query: 187 QSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEE 245
QS QL+ + + G+E+ + + +R E R R EF L++E +++D D++ + EE
Sbjct: 191 QSPQLFKQLLMVAGMERYYQIAHCYRDEDFRADRQ-PEFTQLDMEMSFVDAEDVIAISEE 249
Query: 246 LVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWGDDMG 305
+++ E+ M + P PRISY +A+ S + +G
Sbjct: 250 ILT------------ELWMLIG-----YHIPAPIPRISYADAMRRFGSDKPDLRFG---- 288
Query: 306 ADEERVLTQEF--DRPFFVYGYPKHIKAFYMKEDPNDPRKVL 345
E V EF D F V+ P ++ A M PR+ L
Sbjct: 289 --LELVECTEFFCDTTFRVFQAP-YVGAVVMPGGAAQPRRTL 327
>sp|P57401|SYD_BUCAI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|10038990|dbj|BAB13024.1| (AP001119) aspartyl-tRNA
synthetase [Buchnera sp. APS]
Length = 586
Score = 90.1 bits (220), Expect = 4e-17
Identities = 72/294 (24%), Positives = 135/294 (45%), Gaps = 31/294 (10%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC +I+ K+VKL GWV+ +G+ IF+ +RD TG++Q + + +F+ A
Sbjct: 5 YCGNIRISHVNKKVKLCGWVHKVRNLGQFIFVDMRDYTGLVQVIF--ELKNYKIFKKALN 62
Query: 66 LGRESSVIVEGIVKADER-------APGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
L E + V G V+ E+ G E+ L ++ P+ E + +
Sbjct: 63 LRNEFCIQVFGTVQKREKKNQNIKIRTGEIEILANVLNILNTSKSLPLNFTQEN-NDDSR 121
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--KL 176
L YR+L +RS + ++++ + R ++ ++ + ++ PIL EG
Sbjct: 122 LKYRYLDLRSFDILENLKIRNKITYLIRNFMTKKNFLDIETPILTKSTPEGARDYLVPSR 181
Query: 177 KYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
++ K L QS QL+ + I G+++ + + FR E R+ R EF +++E ++M
Sbjct: 182 NHYGKFYALPQSPQLFKQILMISGIDRYYQIVKCFRDEDLRSDRQ-PEFTQIDIEVSFMS 240
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
I + E L+ + LE+R ++ FP+IS+ EA++
Sbjct: 241 AKKIRNLVENLIKKL---WLEIRNINLK--------------KFPQISFHEAMK 277
>pir||B71442 probable asparagine--tRNA ligase - Arabidopsis thaliana
>gi|2245089|emb|CAB10511.1| (Z97343) asparagine--tRNA
ligase like protein [Arabidopsis thaliana]
>gi|7268482|emb|CAB78733.1| (AL161546) asparagine--tRNA
ligase like protein [Arabidopsis thaliana]
Length = 432
Score = 89.7 bits (219), Expect = 6e-17
Identities = 48/115 (41%), Positives = 70/115 (60%), Gaps = 16/115 (13%)
Query: 297 KIEWGDDMGADEERVLTQEF--DRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAP-- 352
+++WG D+ ++ ER +T+E RP + YPK IKAFYM+E+ +D + V A DML P
Sbjct: 299 QVKWGLDLQSEHERYITEEAFGGRPVIIRDYPKEIKAFYMREN-DDGKTVAAMDMLVPRL 357
Query: 353 -----------EGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGS 396
E GE+IGGS+RE+ + L R+ E ++ + Y WYLDLR+YGS
Sbjct: 358 LMVNDDDGFWPEKIGELIGGSQREERLEVLEARLDELKLNKESYWWYLDLRRYGS 412
>sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437568|pir||F64542 lysine--tRNA ligase (EC 6.1.1.6)
- Helicobacter pylori (strain 26695)
>gi|2313270|gb|AAD07251.1| (AE000538) lysyl-tRNA
synthetase (lysS) [Helicobacter pylori 26695]
Length = 501
Score = 89.3 bits (218), Expect = 8e-17
Identities = 101/447 (22%), Positives = 190/447 (41%), Gaps = 41/447 (9%)
Query: 11 KPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRES 70
+P+ K + G V +GK F+ + D + I+Q +++N + ++ K L
Sbjct: 50 EPKDKEKCESIVGRVKLLRLMGKACFIKVEDESTILQVYVSQNELNDEFKSLKKHLEVGD 109
Query: 71 SVIVEGI---VKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLH-- 125
V+V+G K E + E H+ ++ P+PE S ++ L YR +
Sbjct: 110 IVLVKGFPFATKTGELSIHALEFHILSKTIV------PLPEKFHGLS-DIELRYRQRYLD 162
Query: 126 -IRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKV 182
I +P V + + + ++ + R++ EG+ EV P++ + G + +
Sbjct: 163 LIVNPSVKDVFKKRSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEVE 222
Query: 183 AYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMK 241
YL + +LYL+ I G E V+ + +FR E H EF +E A+ D+++
Sbjct: 223 RYLRIAPELYLKRLIVGGFEAVFEINRNFRNE-GMDHSHNPEFTMIEFYWAYHTYEDLIE 281
Query: 242 VEEELVSYMVQRTLELRKK------EIEMFRDDLTTLKNTEPPFPRIS------YDEAIE 289
+ + L Y++ +TL L K E++ + + + + IS D +
Sbjct: 282 LSKRLFDYLL-KTLNLDSKIIYNDMEVDFNQTSVISYLDALETIGGISKDILEKEDRLLA 340
Query: 290 ILQSKGVKIE----WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPN----DP 341
L +G+K+E +G + + + + P FV YP I + D N D
Sbjct: 341 YLLEQGIKVEPNLTYGKLLAEAFDHFVEHQLINPTFVTQYPIEISPLARRNDSNPNIADR 400
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWYLDLRKYGSVPH 399
++ A G+ E+ ++ + + V KE+G + Y E Y+ +G P
Sbjct: 401 FELFIAGKEIANGFSELNDPLDQLERFKNQVAE-KEKGDEEAQYMDEDYVWALAHGMPPT 459
Query: 400 SGFGLGVERLVAWVLKLDHIRWATLFP 426
+G G+G++RLV + I+ LFP
Sbjct: 460 AGQGIGIDRLVMLLTGAKSIKDVILFP 486
>sp|P57512|SYK_BUCAI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|10039101|dbj|BAB13135.1| (AP001119) lysyl-tRNA
synthetase [Buchnera sp. APS]
Length = 506
Score = 88.9 bits (217), Expect = 1e-16
Identities = 100/446 (22%), Positives = 189/446 (41%), Gaps = 52/446 (11%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGIV 78
V +AG + +GK F ++D G IQ I + + D + K ++ G++
Sbjct: 68 VSIAGRMVQRRIMGKASFFTLQDIEGKIQIYINEKKISSDFYRFHFKKWDIGDIL--GVI 125
Query: 79 KA-DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQAS-PELLLDYRHLH-IRSPKVSAIM 135
+ G ++ + + ++ S P+P+ S E+ R+L I + K+ +I
Sbjct: 126 GTLFKTKTGELSIYCKNVTILNK-SLKPLPDKFHGLSNQEIRYRKRYLDLISNNKLYSIF 184
Query: 136 RVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYLSQSAQLYL 193
+ + +I A R +++ + EV P+L + G + D YL + +LYL
Sbjct: 185 KNRSNIITAIRNFMIENDFLEVETPMLQNIPGGANARPFITYHNEIDSQMYLRIAPELYL 244
Query: 194 EAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQ 252
+ I G E+++ L +FR E + RH EF +E A+ + D+M++ E L + +
Sbjct: 245 KKLIIGGFERIFELNRNFRNE-GVSARHNPEFTMMEAYIAYSNYEDMMELTENLFKSITK 303
Query: 253 RTLELRKKEIEMFRDDLTTLKNTE----PPFPRISYDEAI-------------------E 289
+F+D+ N PF R++ ++I E
Sbjct: 304 F----------LFQDNKIIFNNNNFDFSQPFRRLTMTDSILEFNSTITSSDLKDFYKIRE 353
Query: 290 ILQSKGVKIE--WGDDMGADE--ERVLTQEFDRPFFVYGYPKHIKAFYMKEDPN----DP 341
+S G+K+E WG E E+ + ++ +P F+ YP + + D N D
Sbjct: 354 FAKSIGIKVEKKWGCGQIETEIFEKTVEKKLIQPTFITQYPVEVSPLARRNDINLNITDR 413
Query: 342 RKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEW-YLDLRKYGSVPHS 400
++ G+ E+ +++ + +Q+ +E Y+ Y++ KYG P S
Sbjct: 414 FELFIGGYEIGNGFSELNDVEDQKTRFLNQIQKSNKEDNKNLFYDKEYIEALKYGLPPTS 473
Query: 401 GFGLGVERLVAWVLKLDHIRWATLFP 426
G G+G++RL+ + IR LFP
Sbjct: 474 GLGIGIDRLIMILTNQISIRDVILFP 499
>sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1361209|pir||S56358 lysine--tRNA ligase (EC 6.1.1.6)
- Escherichia coli >gi|7428467|pir||SYECKU lysine--tRNA
ligase (EC 6.1.1.6), thermoinducible - Escherichia coli
>gi|398703|emb|CAA34542.1| (X16542) lysyl-tRNA
synthetase (AA 1-505) [Escherichia coli]
>gi|536974|gb|AAA97029.1| (U14003) lysyl-tRNA synthetase
[Escherichia coli] >gi|1790571|gb|AAC77090.1| (AE000485)
lysine tRNA synthetase, inducible; heat shock protein
[Escherichia coli K12]
Length = 505
Score = 88.5 bits (216), Expect = 1e-16
Identities = 100/441 (22%), Positives = 187/441 (41%), Gaps = 42/441 (9%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF-ETAKKLGRESSVIVEGI 77
V +AG + + +GK F+ ++D G IQ +A++ + E V+ + KK + G
Sbjct: 68 VSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGT 127
Query: 78 VKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP-ELLLDYRHLH-IRSPKVSAIM 135
+ + G +H +L+++ P+P+ E+ R+L I + K
Sbjct: 128 LFKTQT--GELSIHCTELRLLTKALR-PLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTF 184
Query: 136 RVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYLSQSAQLYL 193
V+ ++ A R++++ G+ EV P++ + G + D YL + +LYL
Sbjct: 185 VVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYL 244
Query: 194 EAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQ 252
+ + G E+V+ + +FR E R H EF +EL A+ D D++++ E L + Q
Sbjct: 245 KRLVVGGFERVFEINRNFRNEGISVR-HNPEFTMMELYMAYADYHDLIELTESLFRTLAQ 303
Query: 253 RTLELRK-----------KEIEMF--RDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIE 299
L K K E R+ + + ++D A + +S G+ +E
Sbjct: 304 EVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVE 363
Query: 300 WGDDMGADEERVLTQEFD--------RPFFVYGYPKHIKAFYMKEDPN----DPRKVLAA 347
+G R++T+ FD +P F+ YP + + D N D +
Sbjct: 364 KSWGLG----RIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIG 419
Query: 348 DMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWYLDLRKYGSVPHSGFGLG 405
G+ E+ ++ + + + V K G D + E Y+ +YG P +G G+G
Sbjct: 420 GREIGNGFSELNDAEDQAERFQEQVNA-KAAGDDEAMFYDEDYVTALEYGLPPTAGLGIG 478
Query: 406 VERLVAWVLKLDHIRWATLFP 426
++R++ IR LFP
Sbjct: 479 IDRMIMLFTNSHTIRDVILFP 499
>pdb|1E1O|A Chain A, Lysyl-Trna Synthetase (Lysu) Hexagonal For, Complexed With
L >gi|9954997|pdb|1E1T|A Chain A, Lysyl-Trna Synthetase
(Lysu) Hexagonal Form Complexed With T Lysyl_adenylate
Intermediate >gi|9954998|pdb|1E22|A Chain A, Lysyl-Trna
Synthetase (Lysu) Hexagonal Form Complexed With Lysine
And The Non-Hydrolysable Atp Analogue Amp-Pcp
>gi|9954999|pdb|1E24|A Chain A, Lysyl-Trna Synthetase
(Lysu) Hexagonal Form Complexed With Lysine And Atp And
Mn2+ >gi|1311301|pdb|1LYL|A Chain A, Lysyl-Trna
Synthetase (Lysu) (E.C.6.1.1.6) Complexed With Lysine
>gi|1311305|pdb|1LYL|C Chain C, Lysyl-Trna Synthetase
(Lysu) (E.C.6.1.1.6) Complexed With Lysine
>gi|1311303|pdb|1LYL|B Chain B, Lysyl-Trna Synthetase
(Lysu) (E.C.6.1.1.6) Complexed With Lysine
Length = 504
Score = 88.5 bits (216), Expect = 1e-16
Identities = 100/441 (22%), Positives = 187/441 (41%), Gaps = 42/441 (9%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF-ETAKKLGRESSVIVEGI 77
V +AG + + +GK F+ ++D G IQ +A++ + E V+ + KK + G
Sbjct: 67 VSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGT 126
Query: 78 VKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP-ELLLDYRHLH-IRSPKVSAIM 135
+ + G +H +L+++ P+P+ E+ R+L I + K
Sbjct: 127 LFKTQT--GELSIHCTELRLLTKALR-PLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTF 183
Query: 136 RVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYLSQSAQLYL 193
V+ ++ A R++++ G+ EV P++ + G + D YL + +LYL
Sbjct: 184 VVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYL 243
Query: 194 EAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQ 252
+ + G E+V+ + +FR E R H EF +EL A+ D D++++ E L + Q
Sbjct: 244 KRLVVGGFERVFEINRNFRNEGISVR-HNPEFTMMELYMAYADYHDLIELTESLFRTLAQ 302
Query: 253 RTLELRK-----------KEIEMF--RDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIE 299
L K K E R+ + + ++D A + +S G+ +E
Sbjct: 303 EVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVE 362
Query: 300 WGDDMGADEERVLTQEFD--------RPFFVYGYPKHIKAFYMKEDPN----DPRKVLAA 347
+G R++T+ FD +P F+ YP + + D N D +
Sbjct: 363 KSWGLG----RIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIG 418
Query: 348 DMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWYLDLRKYGSVPHSGFGLG 405
G+ E+ ++ + + + V K G D + E Y+ +YG P +G G+G
Sbjct: 419 GREIGNGFSELNDAEDQAERFQEQVNA-KAAGDDEAMFYDEDYVTALEYGLPPTAGLGIG 477
Query: 406 VERLVAWVLKLDHIRWATLFP 426
++R++ IR LFP
Sbjct: 478 IDRMIMLFTNSHTIRDVILFP 498
>sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1074993|pir||D64110 lysine--tRNA ligase (EC 6.1.1.6)
- Haemophilus influenzae (strain Rd KW20)
>gi|1574141|gb|AAC22865.1| (U32800) lysyl-tRNA
synthetase (lysU) [Haemophilus influenzae Rd]
Length = 502
Score = 88.2 bits (215), Expect = 2e-16
Identities = 112/456 (24%), Positives = 192/456 (41%), Gaps = 64/456 (14%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVI-V 74
G V++AG + + +GK F+ I+D +G IQ +A++ + E V++ ++ +
Sbjct: 61 GIEVQVAGRIMTRRAMGKATFITIQDMSGKIQLYVARDNLPEGVYKDDVGTWDLGDIVGI 120
Query: 75 EGIV---KADERAPGGAEVHVEKLKVIQAVSEFPIPEN-PEQASPELLLDYRHLHIRSPK 130
+G + K DE EV + K ++ P+P+ E+ R+L + S +
Sbjct: 121 KGTLFKTKTDELTVKTTEVQL-LTKALR-----PLPDKFHGLTDQEVRYRQRYLDLISNE 174
Query: 131 VS-AIMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYLSQ 187
S ++ ++ RE+ + +G+ EV P+L + G + D YL
Sbjct: 175 ESRRTFIIRSKVVAGIREYFISKGFMEVETPMLQVIPGGASARPFVTHHNALDVDMYLRI 234
Query: 188 SAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEEL 246
+ +LYL+ + G E+V+ L +FR E + RH EF LE A+ D D+M EEL
Sbjct: 235 APELYLKRLVVGGFERVFELNRNFRNE-GVSVRHNPEFTMLEYYQAYADYHDLMDNTEEL 293
Query: 247 VSYMVQRTLELRKKEIEMFRDDLTTLKNTE----PPFPRIS------------------- 283
LRK I++ + + E PF RI+
Sbjct: 294 ----------LRKLAIDILGTTIVKYGDLEFDFGKPFERITLHDATIKYGADKGIVKEDL 343
Query: 284 --YDEAIEILQSKGVKIE--W--GDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKED 337
+D A + G++++ W G + A E V +P F+ G P I + D
Sbjct: 344 YDFDRAKATAERLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLNGSPAEISPLARRND 403
Query: 338 PN----DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDP---KDYEWYLD 390
N D ++ G+ E+ ++ + +D V KE G D KD ++ +
Sbjct: 404 ENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQV-AAKEAGDDEAMFKDEDFVVA 462
Query: 391 LRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
L ++G P +G GLG++RL IR LFP
Sbjct: 463 L-EHGLPPTAGEGLGIDRLAMLYANAPSIRDVILFP 497
>pir||D83183 lysyl-tRNA synthetase PA3700 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9949865|gb|AAG07088.1|AE004789_8
(AE004789) lysyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 501
Score = 87.8 bits (214), Expect = 2e-16
Identities = 108/461 (23%), Positives = 198/461 (42%), Gaps = 51/461 (11%)
Query: 2 IEKTYCQDIKPELDGKR--VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDV 59
++K Y K EL+ VK+AG + N + F+ ++DS+ +Q + + + E+
Sbjct: 50 LQKQYADKTKEELEAAAIPVKVAGRIMLN----RGSFIVLQDSSERLQVYVNRKTLPEET 105
Query: 60 FETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKV-IQAVSEFPIPENPEQASPELL 118
K + EG++ G +++V+ V + S P+P+ +
Sbjct: 106 LAEIKTWDLGDIIGAEGVLARS----GKGDLYVDMTSVRLLTKSLRPLPDK-HHGLTDTE 160
Query: 119 LDYRHLHIR---SPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATL-- 173
YR ++ + + RV+ +I R +L G+ EV P+L T + GGA
Sbjct: 161 QRYRQRYVDLMVNEETRHTFRVRSQVIAHIRRFLSERGFLEVETPMLQT--IPGGAAAKP 218
Query: 174 FKLKY--FDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELE 230
F+ + D +L + +LYL+ + G EKV+ + +FR E TR H EF LE
Sbjct: 219 FETHHNALDMAMFLRIAPELYLKRLVVGGFEKVFEINRNFRNEGVSTR-HNPEFTMLEFY 277
Query: 231 AAWMDLWDIMKVEEELVSYMVQRTLELRK----KEIEMFRDDLTTLKNTEPPF---PRIS 283
A+ D D M + EEL + Q L ++ F + L + P I+
Sbjct: 278 QAYADYEDNMDLTEELFRELAQSVLGTTDVPYGDKVFHFGEPFVRLSVFDSILKYNPEIT 337
Query: 284 ------YDEAIEILQSKGVKIEWGDDMGADE----ERVLTQEFDRPFFVYGYPKHIKAFY 333
++A I + G K+ + +G + E ++ + ++P F+ YP +
Sbjct: 338 AADLNDVEKARAIAKKAGAKVLGHEGLGKLQVMIFEELVEHKLEQPHFITRYPFEVSPLA 397
Query: 334 MK--EDPN--DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWY- 388
+ EDP+ D ++ Y E+ ++ ED ++ + ++KE+ + Y
Sbjct: 398 RRNDEDPSVTDRFELFIGGREIANAYSEL---NDAEDQAERFMLQVKEKDAGDDEAMHYD 454
Query: 389 ---LDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
++ +YG P +G G+G++RLV + IR LFP
Sbjct: 455 ADFINALEYGMPPTAGEGIGIDRLVMLLTNSPSIRDVILFP 495
>sp|O84546|SYD_CHLTR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437586|pir||G71500 aspartate--tRNA ligase (EC
6.1.1.12) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328981|gb|AAC68144.1| (AE001325) Aspartyl
tRNA Synthetase [Chlamydia trachomatis]
Length = 582
Score = 87.8 bits (214), Expect = 2e-16
Identities = 74/285 (25%), Positives = 133/285 (45%), Gaps = 15/285 (5%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKL 66
C ++ + G+ V+L+GWV+ G +F+ +RD GI Q ++ + ++ + ++
Sbjct: 8 CNELSLDHVGEHVRLSGWVHRYRNHGGVVFIDLRDCFGITQ-IVCRQEENPELHQLMDQV 66
Query: 67 GRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQ--ASPEL 117
E + VEG+V A G EV V L+V+ P + E + EL
Sbjct: 67 RSEWVLCVEGLVCARLEGMENPNLVTGSIEVEVSSLEVLSRAQNLPFSISDEHINVNEEL 126
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT-LFKL 176
L YR+L +R + + + +++A R++L +G+ EV PIL EG L
Sbjct: 127 RLTYRYLDMRRGDILDRLMCRHKVMLACRQYLDEQGFTEVVTPILGKSTPEGARDYLVPS 186
Query: 177 KYFDKVAY-LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
+ + Y L QS QL+ + + GL++ + + FR E R R EF +++E ++
Sbjct: 187 RIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQ-PEFTQIDMEMSFG 245
Query: 235 DLWDIMKVEEELVSYM-VQRTLELRKKEIEMFRDDLTTLKNTEPP 278
D+ V EELV+ + + +EL+ + M + T+ P
Sbjct: 246 GPEDLFPVVEELVARLFAVKGIELKAPFLRMTYQEAKDSYGTDKP 290
>pir||G81412 aspartate--tRNA ligase (EC 6.1.1.12) Cj0640c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968107|emb|CAB75276.1| (AL139075) aspartyl-tRNA
synthetase [Campylobacter jejuni]
Length = 583
Score = 87.0 bits (212), Expect = 4e-16
Identities = 79/284 (27%), Positives = 125/284 (43%), Gaps = 29/284 (10%)
Query: 16 GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVE 75
G+ VKL GWV S G IF+ +RD +GIIQ V N ++ E A E +I E
Sbjct: 15 GQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPND-SKEAHEIASNARNEFVLITE 73
Query: 76 GIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIRS 128
G ++ + G EV V KL + + P E + EL L YR L +R+
Sbjct: 74 GTIRPRGEGLVNPKLKTGEIEVVVSKLTIENESAVPPFAIADESVNEELRLKYRFLDLRN 133
Query: 129 PKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFDKVAY--LS 186
PK+ ++ +AAR L G+ EV PIL EG + + L
Sbjct: 134 PKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARDYLVPSRVHQGEFYALP 193
Query: 187 QSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEE 245
QS QL+ + + G ++ + + FR E R R EF +++E ++ + D++KV E
Sbjct: 194 QSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQ-PEFTQIDVEMSFCEQKDVIKVAET 252
Query: 246 LVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
+ ++F+ K + PF ++ Y +A+E
Sbjct: 253 FLK--------------DIFK---ACGKEIQTPFRQMQYKDAME 279
>sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437582|pir||A64597 aspartate--tRNA ligase (EC
6.1.1.12) - Helicobacter pylori (strain 26695)
>gi|2313739|gb|AAD07682.1| (AE000576) aspartyl-tRNA
synthetase (aspS) [Helicobacter pylori 26695]
Length = 577
Score = 86.6 bits (211), Expect = 5e-16
Identities = 75/294 (25%), Positives = 136/294 (45%), Gaps = 31/294 (10%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
+C +I + GK VK+AGW + G +F+ +RD +G++Q V + +E A +
Sbjct: 5 FCTEISEKDVGKIVKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPS---SKAYEKALE 61
Query: 66 LGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
+ E ++ +G V+ + G E+ +E+L + + PI + + +L
Sbjct: 62 VRSEFVLVAKGKVRLRGAGLENPKLKTGKIEIVLEELIIENKSATPPIEIGNKHVNEDLR 121
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
L YR+L +RSP I +++ + + R L ++G+ E+ PIL EG
Sbjct: 122 LKYRYLDLRSPNSYEIFKLRSEVALITRNTLAQKGFLEIETPILSKTTPEGARDYLVPSR 181
Query: 179 FDKVAY--LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
+ + L QS QL+ + + G+++ + + FR E R R EF ++ E ++ D
Sbjct: 182 VHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQ-PEFTQIDAEMSFCD 240
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
D+M V E+L+ E+F+ T+ PF R+ Y EA+E
Sbjct: 241 ENDVMGVVEDLLQ--------------EIFKAVGHTISK---PFKRMPYKEAME 277
>sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7428466|pir||SYECKT lysine--tRNA ligase (EC 6.1.1.6)
- Escherichia coli >gi|146341|gb|AAA23959.1| (J03795)
herC protein [Escherichia coli]
>gi|887840|gb|AAA83071.1| (U28375) lysyl tRNA synthetase
(LysRS), constitutive [Escherichia coli]
>gi|1789256|gb|AAC75928.1| (AE000372) lysine tRNA
synthetase, constitutive; suppressor of ColE1 mutation
in primer RNA [Escherichia coli K12]
Length = 505
Score = 86.2 bits (210), Expect = 7e-16
Identities = 109/461 (23%), Positives = 195/461 (41%), Gaps = 60/461 (13%)
Query: 13 ELDGKR----------VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF-E 61
E DGK V +AG + + +GK F+ ++D G IQ +A++ + E V+ E
Sbjct: 52 EFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNE 111
Query: 62 TAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP-ELLLD 120
KK + +G K + G +H +L+++ P+P+ E
Sbjct: 112 QFKKWDLGDILGAKG--KLFKTKTGELSIHCTELRLLTKALR-PLPDKFHGLQDQEARYR 168
Query: 121 YRHLHIRSPKVSA-IMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLK 177
R+L + S S +V+ ++ R++++ G+ EV P++ + G +
Sbjct: 169 QRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHN 228
Query: 178 YFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
D YL + +LYL+ + G E+V+ + +FR E R H EF +EL A+ D
Sbjct: 229 ALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVR-HNPEFTMMELYMAYADY 287
Query: 237 WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE------- 289
D++++ E L + Q L + E+ D+T + PF +++ EAI+
Sbjct: 288 KDLIELTESLFRTLAQDILG----KTEVTYGDVTL--DFGKPFEKLTMREAIKKYRPETD 341
Query: 290 ------------ILQSKGVKIE--WGDDMGADE--ERVLTQEFDRPFFVYGYPKHIKAFY 333
I +S G+ +E WG E E V +P F+ YP +
Sbjct: 342 MADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLA 401
Query: 334 MKEDPN----DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRI--KEEGMDPKDY-- 385
+ D N D + G+ E+ ++ ED + + ++ K+ G D +
Sbjct: 402 RRNDVNPEITDRFEFFIGGREIGNGFSEL---NDAEDQAQRFLDQVAAKDAGDDEAMFYD 458
Query: 386 EWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
E Y+ ++G P +G G+G++R+V IR LFP
Sbjct: 459 EDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFP 499
>pdb|1BBU|A Chain A, Lysyl-Trna Synthetase (Lyss) Complexed With Lysine
>gi|11513776|pdb|1BBW|A Chain A, Lysyl-Trna Synthetase
(Lyss)
Length = 504
Score = 86.2 bits (210), Expect = 7e-16
Identities = 109/461 (23%), Positives = 195/461 (41%), Gaps = 60/461 (13%)
Query: 13 ELDGKR----------VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF-E 61
E DGK V +AG + + +GK F+ ++D G IQ +A++ + E V+ E
Sbjct: 51 EFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNE 110
Query: 62 TAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP-ELLLD 120
KK + +G K + G +H +L+++ P+P+ E
Sbjct: 111 QFKKWDLGDILGAKG--KLFKTKTGELSIHCTELRLLTKALR-PLPDKFHGLQDQEARYR 167
Query: 121 YRHLHIRSPKVSA-IMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLK 177
R+L + S S +V+ ++ R++++ G+ EV P++ + G +
Sbjct: 168 QRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHN 227
Query: 178 YFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
D YL + +LYL+ + G E+V+ + +FR E R H EF +EL A+ D
Sbjct: 228 ALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVR-HNPEFTMMELYMAYADY 286
Query: 237 WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE------- 289
D++++ E L + Q L + E+ D+T + PF +++ EAI+
Sbjct: 287 KDLIELTESLFRTLAQDILG----KTEVTYGDVTL--DFGKPFEKLTMREAIKKYRPETD 340
Query: 290 ------------ILQSKGVKIE--WGDDMGADE--ERVLTQEFDRPFFVYGYPKHIKAFY 333
I +S G+ +E WG E E V +P F+ YP +
Sbjct: 341 MADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLA 400
Query: 334 MKEDPN----DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRI--KEEGMDPKDY-- 385
+ D N D + G+ E+ ++ ED + + ++ K+ G D +
Sbjct: 401 RRNDVNPEITDRFEFFIGGREIGNGFSEL---NDAEDQAQRFLDQVAAKDAGDDEAMFYD 457
Query: 386 EWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
E Y+ ++G P +G G+G++R+V IR LFP
Sbjct: 458 EDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFP 498
>sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437569|pir||S77380 lysine--tRNA ligase (EC 6.1.1.6)
- Synechocystis sp. (strain PCC 6803)
>gi|1652562|dbj|BAA17483.1| (D90906) lysyl-tRNA
synthetase [Synechocystis sp.]
Length = 510
Score = 86.2 bits (210), Expect = 7e-16
Identities = 117/476 (24%), Positives = 196/476 (40%), Gaps = 72/476 (15%)
Query: 2 IEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVG----- 56
+++TY E +V +AG + + +GK F ++D +G IQ + K +
Sbjct: 45 LQETYRDLSNGEEVDLKVAIAGRILARRVMGKLAFFTLQDESGTIQLYLEKQRLTEHMPE 104
Query: 57 -EDVFETAKKLGRESSVI-VEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPE------ 108
E+ F KK+ ++ V G +K E+ G V+V+ V+ S P+P+
Sbjct: 105 LENAFNLLKKITDVGDILGVTGTLKRTEK--GELSVYVQTYAVL-TKSLLPLPDKWHGLT 161
Query: 109 NPEQASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPIL--VTGA 166
+ E+ + +D I +P V R + + A R +L ++G+ E+ P+L +G
Sbjct: 162 DTEKRYRQRYVDL----IVNPTVRQTFRRRAQITAAIRRYLDKQGFIEIETPVLQGESGG 217
Query: 167 VEGGATLFKLKYFDKVAYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFW 225
E + YL + +L+L+ + G EKV+ L FR E T RH EF
Sbjct: 218 AEARPFITHHNTLGMPLYLRIATELHLKRLVVGGFEKVFELGRIFRNEGVST-RHNPEFT 276
Query: 226 HLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYD 285
+E+ A++D ++M + E LV+ Q L K + DLT PP+ RI+
Sbjct: 277 SIEVYQAYVDYNEMMALTEALVTTAAQAVLGTLKITYQGEEIDLT------PPWKRITMH 330
Query: 286 EAIEILQSKGVKIEWGDDM------------GADEE-----RVLTQEFD--------RPF 320
EA+++ G+ D+ G E+ +L F+ +P
Sbjct: 331 EAVQL--ETGIDFSQFTDLETAKQAATKAGIGVPEDCPSLGHLLNHAFEQKVEGTLMQPT 388
Query: 321 FVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGM 380
F+ +P I K + P V ++ YG + S E D + QR + E
Sbjct: 389 FIIDFPVEISPL-AKPHRSKPGLVERFELFV---YGRELANSFSELT-DPIDQRSRLEAQ 443
Query: 381 DPKDY----------EWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
K E +L +YG P G G+G++RLV + IR FP
Sbjct: 444 AAKKAAGDLEAHSVDEDFLTALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVIAFP 499
>pir||E81660 aspartyl-tRNA synthetase TC0829 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190856|gb|AAF39629.1| (AE002349)
aspartyl-tRNA synthetase [Chlamydia muridarum]
Length = 582
Score = 85.8 bits (209), Expect = 9e-16
Identities = 77/307 (25%), Positives = 138/307 (44%), Gaps = 31/307 (10%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKL 66
C ++ G+ V+L+GWV+ G +F+ +RD GI Q ++ + ++ ++
Sbjct: 8 CNELSLNHVGEHVRLSGWVHRYRNHGGVVFIDLRDRFGITQ-IVCRQEENPELHRLMDQV 66
Query: 67 GRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQ--ASPEL 117
E + VEG+V A G EV V L+V+ P + E + EL
Sbjct: 67 RSEWVLCVEGLVCARLGGMENPNLVTGSIEVEVSHLEVLSRAQNLPFSISDEHINVNEEL 126
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGAT-LFKL 176
L YR+L +R + + + +++A R++L +G+ EV P+L EG L
Sbjct: 127 RLTYRYLDMRRGDIVDRLMCRHKVMLACRQYLDEQGFTEVVTPVLGKSTPEGARDYLVPS 186
Query: 177 KYFDKVAY-LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
+ + Y L QS QL+ + + GL++ + + FR E R R EF +++E ++
Sbjct: 187 RIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQ-PEFSQIDMEMSFG 245
Query: 235 DLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSK 294
D+ + EELV+ R ++ E+ + PF R++Y EA E +
Sbjct: 246 GPEDLFPIVEELVT----RLFAVKGIELSI-------------PFQRMTYQEAKEFYGTD 288
Query: 295 GVKIEWG 301
+ +G
Sbjct: 289 KPDLRFG 295
>sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1072959|pir||A55589 lysine--tRNA ligase (EC 6.1.1.6)
- Thermus aquaticus >gi|486665|emb|CAA50039.1| (X70708)
lysine--tRNA ligase [Thermus thermophilus]
Length = 492
Score = 85.4 bits (208), Expect = 1e-15
Identities = 114/443 (25%), Positives = 186/443 (41%), Gaps = 48/443 (10%)
Query: 17 KRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEG 76
+ V +AG + + R+GK F + D TG IQ +++ + +E KKL + V G
Sbjct: 52 EEVAVAGRLVALRRMGKVTFAHLLDETGRIQLYFQRDLTPK--YELLKKLDVGDILGVRG 109
Query: 77 IVKADERAPGGAEVHVEKLKVIQAVSEF-PIPENPEQA-SPELLLDYRHLH-IRSPKVSA 133
+ EV V+ L V P+P+ E+ R+L I +P+V
Sbjct: 110 HPFTTKTG----EVTVKVLDWTPLVKSLHPLPDKWHGLRDKEVRYRQRYLDLIVNPEVRE 165
Query: 134 IMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYLSQSAQL 191
+ R + ++ R + +G+ EV PIL TG E D YL S +L
Sbjct: 166 VFRRRSEIVRYIRRFFEAKGFLEVETPILQPTTGGAEARPFKTYHNALDHEFYLRISLEL 225
Query: 192 YLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYM 250
YL+ + G EKV+ + +FR E H EF LE A+ D D+ + EEL+S +
Sbjct: 226 YLKRLLVGGYEKVFEIGRNFRNE-GIDHNHNPEFTMLEAYWAYADYQDMAGLVEELLSGL 284
Query: 251 VQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIE---------WG 301
V + + + N +PPF RIS+ EA++ + G+ + W
Sbjct: 285 VLHLFGSHEVPYQ------GRVLNFKPPFRRISFVEALK--EKAGLPFDPLDLERLRLWA 336
Query: 302 DDMGADEERV-------------LTQEFDRPFFVYGYPKHIK--AFYMKEDPNDPRK--V 344
D + +V + E P FV+ +P I A +E P + +
Sbjct: 337 DAHHPELSQVPNYKLLDKLFGIYVEPELQDPTFVFDFPLAISPLAKRHREKPGLVERWDL 396
Query: 345 LAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMD-PKDYEWYLDLRKYGSVPHSGFG 403
A M Y E+ ++ + + + +R KE + P+ E +L +YG P +G G
Sbjct: 397 YAGGMELAPCYSELNDPLDQRERFLEQARRRKEGDEEAPEPDEDFLLALEYGMPPAAGLG 456
Query: 404 LGVERLVAWVLKLDHIRWATLFP 426
LG++RL + +R LFP
Sbjct: 457 LGIDRLAMLLTDQPSLRDVLLFP 479
>emb|CAB89697.1| (AJ276418) putative lysyl tRNA synthetase [Xanthomonas campestris
pv. campestris]
Length = 505
Score = 85.4 bits (208), Expect = 1e-15
Identities = 110/452 (24%), Positives = 184/452 (40%), Gaps = 54/452 (11%)
Query: 13 ELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSV 72
E + VKLAG + + +GK F I+D +G +Q + NV+G D + K V
Sbjct: 64 EAADRSVKLAGRLMAKRVMGKASFAQIQDESGRVQLFLQGNVLG-DAYTAFKGWDVGDIV 122
Query: 73 IVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLHIR---SP 129
VEG + + G V L+++ S P+P+ S ++ YR ++ +P
Sbjct: 123 AVEGGLTRTKT--GELSVKATALRLLTK-SLRPLPDKWHGLS-DVEQRYRQRYVDLIVTP 178
Query: 130 KVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKL----KYFDKVAYL 185
+ + + +I A R WL + EV P++ + GGAT D YL
Sbjct: 179 EAREVFIKRSKIIRAIRAWLDARRFLEVETPMM--HYIPGGATAKPFTTHHNALDLDLYL 236
Query: 186 SQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEE 244
+ +LYL+ + G LE+V+ + +FR E TR H EF LEL A+ +IM + E
Sbjct: 237 RVAPELYLKRLVVGGLERVYEINRNFRNEGVSTR-HNPEFTMLELYEAYATYHEIMDLTE 295
Query: 245 ELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE--------------- 289
+++ Q L + + DL P F R DEA+
Sbjct: 296 QVIRDTAQGVLGTTQVSWDGADIDLA------PAFRRWRMDEAVRHHNPEISAADCTDRA 349
Query: 290 --ILQSKGVKIE------WGDDMGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPN-- 339
+ + +KI+ WG + E + +P F+ +P + D
Sbjct: 350 ALLRHCERLKIKVKPSYGWGKLLLEIFESTVEHTLVQPTFITDHPVEVSPLARASDTEPG 409
Query: 340 --DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEW---YLDLRKY 394
D ++ G+ E+ ++ + VQ ++G D + + Y+ +Y
Sbjct: 410 YTDRFELFINGKELANGFSELNDPEDQAARFQAQVQA--KDGGDDEAMHYDADYIRALEY 467
Query: 395 GSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
G P G G+G++RLV + IR LFP
Sbjct: 468 GMAPTGGLGIGIDRLVMLLTGSTSIRDVLLFP 499
>sp|Q9ZE17|SYD_RICPR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437607|pir||F71724 aspartate--tRNA ligase (EC
6.1.1.12) - Rickettsia prowazekii
>gi|3860712|emb|CAA14613.1| (AJ235270) ASPARAGINYL-TRNA
SYNTHETASE (aspS) [Rickettsia prowazekii]
Length = 605
Score = 85.0 bits (207), Expect = 1e-15
Identities = 76/294 (25%), Positives = 133/294 (44%), Gaps = 30/294 (10%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKL 66
C +++ G+ VKL+GWV+ G +F+ +RD GI Q V + + A +L
Sbjct: 9 CNELQLSNVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGITQIVFTDQ--NQQLMYDASRL 66
Query: 67 GRESSVIVEGIVKA------DERAPGGAEVHVEKLKVIQAVSEFPIP---ENPEQASPEL 117
ES + V G V A + + P G V V ++ I + P+P N ++A E
Sbjct: 67 CYESVITVSGTVVARSLDTINNKLPTG-YVEVLAMECIVESASSPLPFVINNEKEAPEES 125
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--K 175
L +R L +R K+ + ++ +I R ++ G+ E+ PIL + + EG
Sbjct: 126 RLKHRFLDLRREKLHNNIILRSQVIAHIRHLMIARGFTELQTPILTSSSPEGARDFLVPS 185
Query: 176 LKYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
+ K L Q+ Q + + + G ++ + + P FR E +R R EF+ L+LE +++
Sbjct: 186 RIHPGKFYALPQAPQQFKQLLMVAGFDRYFQIAPCFRDEDARADRSPGEFYQLDLEMSFV 245
Query: 235 DLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
DI E ++ + + T+ NT PF RI Y+E++
Sbjct: 246 TQEDIFNTIEPVLYDLFTKFTN-------------KTVSNT--PFVRIPYNESM 284
>sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437584|pir||S75048 aspartate--tRNA ligase (EC
6.1.1.12) - Synechocystis sp. (strain PCC 6803)
>gi|1652993|dbj|BAA17910.1| (D90910) aspartyl-tRNA
synthetase [Synechocystis sp.]
Length = 599
Score = 84.7 bits (206), Expect = 2e-15
Identities = 77/298 (25%), Positives = 142/298 (46%), Gaps = 33/298 (11%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC D++ G+ V L GWV G IFL +RD GI+Q + + + A+
Sbjct: 5 YCGDLRTTHLGETVTLYGWVDRRRDHGGVIFLDLRDRQGIVQIASSPDQTPAS-YPVAEG 63
Query: 66 LGRESSVIVEGIV------KADERAP-GGAEVHVEKLKVIQAVSE---FPIPEN-PEQAS 114
L E V V G+V +E+ P G E++ + + ++ V++ F + + EQ
Sbjct: 64 LRNEYVVQVTGVVSKRPPESLNEKIPTGEIEIYADSIILLNGVNQQLPFVVSSHEAEQVR 123
Query: 115 PELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLL-REGWHEVFPPILVTGAVEGGATL 173
++ L YR+L +R ++S ++++ ++ A R +L +E + E+ PIL EG
Sbjct: 124 EDVRLKYRYLDLRRARLSQNLQLRHQVVKAMRRFLEDQENFLEIETPILTRSTPEGARDY 183
Query: 174 FKLKYFDKVAY--LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELE 230
+ + L QS QL+ + + G+++ + + FR E R R EF L++E
Sbjct: 184 LVPSRVNPGEWYALPQSPQLFKQLLMVAGMDRYYQIARCFRDEDLRADRQ-PEFTQLDME 242
Query: 231 AAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
++M +I+ + E L+ ++ + K I++ R PFPR++Y E++
Sbjct: 243 MSFMGQEEILDLNEALICHIFKVV-----KNIDLPR-----------PFPRLTYQESM 284
>sp|Q9ZMP8|SYK_HELPJ LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437567|pir||F71965 lysine--tRNA ligase (EC 6.1.1.6)
- Helicobacter pylori (strain J99)
>gi|4154685|gb|AAD05751.1| (AE001455) LYSYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 501
Score = 84.7 bits (206), Expect = 2e-15
Identities = 100/431 (23%), Positives = 183/431 (42%), Gaps = 49/431 (11%)
Query: 31 VGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGI---VKADERAPGG 87
+GK F+ I D + I+Q +++N + ++ K L V+V+G K E +
Sbjct: 70 MGKACFIKIEDESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSIHA 129
Query: 88 AEVHVEKLKVIQAVSEFPIPENPEQASPELLLDYRHLH---IRSPKVSAIMRVKETLIMA 144
E H+ ++ P+PE S ++ L YR + I +P V + + + ++ +
Sbjct: 130 LEFHILSKTIV------PLPEKFHGLS-DIELRYRQRYLDLIVNPGVKDVFKKRSLIVSS 182
Query: 145 AREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYLSQSAQLYLEAAIF-GLE 201
R++ EG+ EV P++ + G + + YL + +LYL+ I G E
Sbjct: 183 VRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEIERYLRIAPELYLKRLIVGGFE 242
Query: 202 KVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKK- 260
V+ + +FR E H EF +E A+ D++++ + L Y++ +TL L K
Sbjct: 243 AVFEINRNFRNE-GMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLL-KTLNLDSKI 300
Query: 261 -----EIEMFRDDLTTLKNTEPPFPRIS------YDEAIEILQSKGVKIEWGDDMGADEE 309
E++ + + + + IS D + L +G+K+E G
Sbjct: 301 IYNDMEVDFNQTSVISYLDALETIGGISKGILEKEDRLLAYLLEQGIKVEPNLTHG---- 356
Query: 310 RVLTQEFD--------RPFFVYGYPKHIKAFYMKEDPN----DPRKVLAADMLAPEGYGE 357
++L + FD P FV YP I + D N D ++ A G+ E
Sbjct: 357 KLLAEAFDHFVEHKLINPTFVTEYPIEISPLARRNDSNPNIADRFELFIAGKEIANGFSE 416
Query: 358 IIGGSEREDNYDKLVQRIKEEGMDPKDY--EWYLDLRKYGSVPHSGFGLGVERLVAWVLK 415
+ ++ + + V KE+G + Y E Y+ + P +G G+G++RLV +
Sbjct: 417 LNDPLDQLERFKNQVAE-KEKGDEEAQYMDEDYVWALAHEMPPTAGQGIGIDRLVMLLTG 475
Query: 416 LDHIRWATLFP 426
I+ LFP
Sbjct: 476 AKSIKDVILFP 486
>sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68534|pir||SYECD aspartate--tRNA ligase (EC
6.1.1.12) - Escherichia coli >gi|9256904|pdb|1EQR|A
Chain A, Crystal Structure Of Free Aspartyl-Trna
Synthetase From Escherichia Coli >gi|9256905|pdb|1EQR|B
Chain B, Crystal Structure Of Free Aspartyl-Trna
Synthetase From Escherichia Coli >gi|9256906|pdb|1EQR|C
Chain C, Crystal Structure Of Free Aspartyl-Trna
Synthetase From Escherichia Coli
>gi|41015|emb|CAA37856.1| (X53863) aspartate-tRNA ligase
[Escherichia coli] >gi|1736513|dbj|BAA15677.1| (D90829)
Aspartate--tRNA ligase (EC 6.1.1.12) [Escherichia coli]
>gi|1788173|gb|AAC74936.1| (AE000280) aspartate tRNA
synthetase [Escherichia coli K12]
Length = 590
Score = 84.3 bits (205), Expect = 3e-15
Identities = 67/255 (26%), Positives = 116/255 (45%), Gaps = 14/255 (5%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC ++ G++V L GWV +G IF+ +RD GI+Q + D + A +
Sbjct: 5 YCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPD--RADALKLASE 62
Query: 66 LGRESSVIVEGIVKA-DER------APGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
L E + V G V+A DE+ A G EV L +I P+ N + E
Sbjct: 63 LRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSN-HVNTEEAR 121
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
L YR+L +R P+++ ++ + + R ++ G+ ++ P+L EG
Sbjct: 122 LKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSR 181
Query: 179 FDKVAY--LSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
K + L QS QL+ + + G ++ + + FR E R R EF +++E ++M
Sbjct: 182 VHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDVETSFMT 240
Query: 236 LWDIMKVEEELVSYM 250
+ +V E LV ++
Sbjct: 241 APQVREVMEALVRHL 255
>pdb|1C0A|A Chain A, Crystal Structure Of The E. Coli Aspartyl-Trna Synthetase
: Trnaasp : Aspartyl-Adenylate Complex
Length = 585
Score = 84.3 bits (205), Expect = 3e-15
Identities = 67/255 (26%), Positives = 116/255 (45%), Gaps = 14/255 (5%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC ++ G++V L GWV +G IF+ +RD GI+Q + D + A +
Sbjct: 5 YCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPD--RADALKLASE 62
Query: 66 LGRESSVIVEGIVKA-DER------APGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
L E + V G V+A DE+ A G EV L +I P+ N + E
Sbjct: 63 LRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSN-HVNTEEAR 121
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
L YR+L +R P+++ ++ + + R ++ G+ ++ P+L EG
Sbjct: 122 LKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSR 181
Query: 179 FDKVAY--LSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
K + L QS QL+ + + G ++ + + FR E R R EF +++E ++M
Sbjct: 182 VHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDVETSFMT 240
Query: 236 LWDIMKVEEELVSYM 250
+ +V E LV ++
Sbjct: 241 APQVREVMEALVRHL 255
>pir||S69892 lysine--tRNA ligase (EC 6.1.1.6) - Mycoplasma hominis
Length = 488
Score = 82.7 bits (201), Expect = 8e-15
Identities = 107/433 (24%), Positives = 189/433 (42%), Gaps = 62/433 (14%)
Query: 36 FLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKL 95
F+ ++D+ G +Q K + E +T + + V G + + A V +
Sbjct: 72 FIVLQDNCGQMQIYANKKTLNESSAKTFSLMDFGDILSVRGTLS---KTNTDALVIKAQD 128
Query: 96 KVIQAVSEFPIPE------NPEQASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWL 149
V+ S P+P+ +PE+ + +D I + K ++ +I RE+
Sbjct: 129 IVLLTKSLKPLPDKFHGLVDPEERRRQRYVDL----IMNEKTRNTFVMRTQIIKGIREYF 184
Query: 150 LREGWHEVFPPILVTGAVEGGATLFKLKYF----DKVAYLSQSAQLYLEAAIFG-LEKVW 204
+ EV PIL + GGA F ++ YL + +L L+ I G L++V+
Sbjct: 185 DSLNYIEVDTPIL--NPILGGAAAKPFITFYNALNRNFYLRIATELPLKKLIVGGLDRVY 242
Query: 205 SLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEM 264
+ FR E T H EF +E A+ DLW +M+ E + +++ + KE++
Sbjct: 243 EIGRIFRNEGVDTT-HNPEFTSIEFYEAYSDLWGMMERTEGVFKHLINK---FNIKEVKF 298
Query: 265 FRDDLTTLKNTEPPFPRISYDEAI-----------------EILQSKGVKIE----WGDD 303
D+T PF R++ +AI E+ + G+KIE +G
Sbjct: 299 NGFDITF----NFPFKRVNMIDAISEKINVDIRKLNEEQMFELAKKHGIKIEKFFRYGHI 354
Query: 304 MGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADM-LAPEGYGEIIGGS 362
+ E+ + + P FVYG+P I DP+D R L A++ + + + + +
Sbjct: 355 INELFEKYVEETLIEPTFVYGHPIEISPL-AAIDPDDKRFTLRAELFIGTKEFANMF--T 411
Query: 363 EREDNYDKLVQRI------KEEGMDP-KDYEW-YLDLRKYGSVPHSGFGLGVERLVAWVL 414
E D D+L QR KE G + + +W +++ +YG P G G+G++RL+ +
Sbjct: 412 ELNDPIDQL-QRFENQLLEKENGNEEANEIDWDFVNALEYGMPPTGGSGIGIDRLIMLLT 470
Query: 415 KLDHIRWATLFPR 427
+ D IR LFP+
Sbjct: 471 QNDSIRDVVLFPQ 483
>sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2947034|gb|AAC05432.1| (L43549) aspartyl-tRNA
synthetase [Buchnera aphidicola]
Length = 584
Score = 82.7 bits (201), Expect = 8e-15
Identities = 68/250 (27%), Positives = 115/250 (45%), Gaps = 12/250 (4%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC +I+ K V L GWV+ + IF+ +RD TGI+Q V K VF A
Sbjct: 5 YCGNIRIIDLHKSVILCGWVHKIRNFSQFIFIDMRDWTGIVQLVFEKK--NNKVFTKAVN 62
Query: 66 LGRESSVIVEGIVKA-----DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLD 120
L ES + V GIVK + G E+ V K+KV P+ + ++ ++ L
Sbjct: 63 LKNESCIQVIGIVKKRNANNNNLDTGEIEILVNKIKVFNISKNLPL-DYSNNSNDDIRLK 121
Query: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--KLKY 178
YR+L +R ++ ++++ + R ++ + + ++ P L EG Y
Sbjct: 122 YRYLDLRRSELLENLKIRNKITHLIRIFMENKNFLDIETPFLTKSTPEGARDYLVPSRNY 181
Query: 179 FDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW 237
L QS QL+ + I G++K + + FR E R+ R EF +++EA+++
Sbjct: 182 PGNFYALPQSPQLFKQILMISGIDKYYQIVKCFRDEDLRSDRQ-PEFTQIDIEASFVSST 240
Query: 238 DIMKVEEELV 247
I + E L+
Sbjct: 241 KIRNLVETLI 250
>sp|Q9ZLL9|SYD_HELPJ ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437600|pir||C71916 aspartate--tRNA ligase (EC
6.1.1.12) - Helicobacter pylori (strain J99)
>gi|4155111|gb|AAD06143.1| (AE001489) ASPARTYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 579
Score = 82.3 bits (200), Expect = 1e-14
Identities = 72/294 (24%), Positives = 134/294 (45%), Gaps = 31/294 (10%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
+C +I + GK +K+AGW + G +F+ +RD +G++Q V + +E A +
Sbjct: 5 FCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPS---SKAYEKALE 61
Query: 66 LGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
+ E ++ +G + + G E+ +E+L + + PI + + +L
Sbjct: 62 VRSEFVLVAKGKARLRGAGLENPKLKTGKIEIVLEELVIENKSATPPIEIGNKSVNEDLR 121
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
L YR+L +RS I +++ + + R L ++G+ E+ PIL EG
Sbjct: 122 LKYRYLDLRSLNAYEIFKLRSEVALITRNALAQKGFLEIETPILSKTTPEGARDYLVPSR 181
Query: 179 FDKVAY--LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
+ + L QS QL+ + + G+++ + + FR E R R EF ++ E ++ D
Sbjct: 182 VHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQ-PEFTQIDAEMSFCD 240
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
D+M V E+L+ E+F+ T+ PF R+ Y EA+E
Sbjct: 241 EDDVMGVVEDLLQ--------------EIFKAIGHTISK---PFKRMPYKEAME 277
>sp|P41908|SYNC_SACDO PUTATIVE ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA
LIGASE) (ASNRS) >gi|2133232|pir||S43538 DED81D protein -
yeast (Saccharomyces sp.) (fragment)
>gi|471339|emb|CAA52090.1| (X73886) DED81D
[Saccharomyces douglasii]
Length = 87
Score = 81.9 bits (199), Expect = 1e-14
Identities = 38/87 (43%), Positives = 55/87 (62%), Gaps = 1/87 (1%)
Query: 348 DMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVE 407
D+L P GEI GGS R D+ ++L+ K EG+D Y W++D RKYG+ PH G+G+G E
Sbjct: 2 DVLMPN-VGEITGGSMRIDDMNELMAGFKREGIDTDAYYWFIDQRKYGTCPHGGYGIGTE 60
Query: 408 RLVAWVLKLDHIRWATLFPRTPARIYP 434
R++AW+ +R +L+PR R P
Sbjct: 61 RILAWLCDRFTVRDCSLYPRFSGRCKP 87
>gb|AAA24096.1| (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1.6) [Escherichia
coli]
Length = 501
Score = 81.5 bits (198), Expect = 2e-14
Identities = 97/442 (21%), Positives = 178/442 (39%), Gaps = 48/442 (10%)
Query: 19 VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGIV 78
V +AG + + +GK F+ ++D G IQ +A++ + E V+ K +I G +
Sbjct: 68 VSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGAGTL 127
Query: 79 KADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP-ELLLDYRHLH-IRSPKVSAIMR 136
+ G +H +L+++ P+P+ E+ R+L I + K
Sbjct: 128 FKTQT--GELSIHCTELRLLTKALR-PLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFV 184
Query: 137 VKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGATLFKLKYFDKVAYLSQSAQLYLE 194
V+ ++ A R++++ G+ EV P++ + G + D Y + +LYL+
Sbjct: 185 VRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYARIAPELYLK 244
Query: 195 AAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQR 253
+ G E+V+ RRH EF +EL A+ D D++++ E L + Q
Sbjct: 245 RLVVGGFERVFEHV----TRNEGIRRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQE 300
Query: 254 TLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE-------------------ILQSK 294
L K D PF +++ EAI+ + +S
Sbjct: 301 VLGTTKVTYGEHVFDFGK------PFEKLTMREAIKKYRPETDMADLDNFDARKALAESI 354
Query: 295 GVKIE--WGDDMGADE--ERVLTQEFDRPFFVYGYPKHIKAFYMKEDPN----DPRKVLA 346
G+ +E WG E + V+ +P F+ YP + + D N D +
Sbjct: 355 GITVEKSWGLGRSVTEIFDEVVEGHVIQPSFITEYPAEVSPLARRNDVNPEITDRFEFFI 414
Query: 347 ADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EWYLDLRKYGSVPHSGFGL 404
G+ E+ ++ + + + V K G D + E Y+ +YG P +G G+
Sbjct: 415 GGREIGNGFSELNDAEDQAERFQEQVNA-KAAGDDEAMFYDEDYVTALEYGLPPTAGLGI 473
Query: 405 GVERLVAWVLKLDHIRWATLFP 426
G++R++ IR LFP
Sbjct: 474 GIDRMIMLFTNSHTIRDVILFP 495
>pir||G81195 aspartyl-tRNA synthetase NMB0466 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225693|gb|AAF40903.1| (AE002403) aspartyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 602
Score = 80.4 bits (195), Expect = 4e-14
Identities = 71/293 (24%), Positives = 129/293 (43%), Gaps = 30/293 (10%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC I + + V + GWV+ G IF+ +RD GI+Q VI + + F A
Sbjct: 5 YCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDT--PEAFAAADS 62
Query: 66 LGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
E + + G V+ D+ G E+ ++++V+ A + P + E S +
Sbjct: 63 SRNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISENVR 122
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--KL 176
L R + +R P + +R++ + M R +L +G+ ++ P+L EG
Sbjct: 123 LTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVPSR 182
Query: 177 KYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
+ + L QS QL+ + + G ++ + +T FR E R R EF ++LE ++++
Sbjct: 183 VHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQ-PEFTQIDLETSFLN 241
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
+IM + E + ++F+D L FPR+ Y EA+
Sbjct: 242 EDEIMDITEGMAK--------------QVFKDALNV---DLGDFPRMPYSEAM 277
>sp|Q9Z7P2|SYD_CHLPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437604|pir||G72052 aspartate--tRNA ligase (EC
6.1.1.12) - Chlamydophila pneumoniae (strains CWL029 and
AR39) >gi|4376961|gb|AAD18801.1| (AE001648) Aspartyl
tRNA Synthetase [Chlamydophila pneumoniae CWL029]
>gi|7189021|gb|AAF37971.1| (AE002172) aspartyl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
>gi|8979034|dbj|BAA98869.1| (AP002547) aspartyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 584
Score = 80.0 bits (194), Expect = 5e-14
Identities = 72/284 (25%), Positives = 129/284 (45%), Gaps = 19/284 (6%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKL 66
C ++ G+ V+LAGWV+ G +F+ +RD GI Q V ++ E + + +
Sbjct: 8 CNELTSNHIGENVQLAGWVHRYRNHGGVVFIDLRDRFGITQIVCREDEQPE-LHQRLDAV 66
Query: 67 GRESSVIVEGIV-------KADERAPGGAEVHVEKLKVIQAVSEFP--IPENPEQASPEL 117
E + V G V + A G EV V +V+ P I ++ + EL
Sbjct: 67 RSEWVLSVRGKVCPRLAGMENPNLATGHIEVEVASFEVLSKSQNLPFSIADDHINVNEEL 126
Query: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--K 175
L+YR+L +R + + + +++A R ++ +G+ E+ P+L EG
Sbjct: 127 RLEYRYLDMRRGDIIEKLLCRHQVMLACRNFMDAQGFTEIVTPVLGKSTPEGARDYLVPS 186
Query: 176 LKYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
Y K L QS QL+ + + GL++ + + FR E R R EF +++E ++
Sbjct: 187 RIYPGKFYALPQSPQLFKQLLMVGGLDRYFQIATCFRDEDLRADRQ-PEFAQIDIEMSFG 245
Query: 235 DLWDIMKVEEELVSYM-----VQRTLELRKKEIEMFRDDLTTLK 273
D D++ + E+LV+ + ++ L L K + +D T K
Sbjct: 246 DTQDLLPIIEQLVATLFATQGIEIPLPLAKMTYQEAKDSYGTDK 289
>pir||F81831 aspartate--tRNA ligase (EC 6.1.1.12) NMA2019 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380648|emb|CAB85238.1| (AL162757) aspartyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 602
Score = 80.0 bits (194), Expect = 5e-14
Identities = 71/293 (24%), Positives = 129/293 (43%), Gaps = 30/293 (10%)
Query: 6 YCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKK 65
YC I + + V + GWV+ G IF+ +RD GI+Q VI + + F A
Sbjct: 5 YCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDT--PEAFAAADS 62
Query: 66 LGRESSVIVEGIVKA-------DERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELL 118
E + + G V+ D+ G E+ ++++V+ A + P + E S +
Sbjct: 63 ARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISENVR 122
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLF--KL 176
L R + +R P + +R++ + M R +L +G+ ++ P+L EG
Sbjct: 123 LTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVPSR 182
Query: 177 KYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
+ + L QS QL+ + + G ++ + +T FR E R R EF ++LE ++++
Sbjct: 183 VHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQ-PEFTQIDLETSFLN 241
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI 288
+IM + E + ++F+D L FPR+ Y EA+
Sbjct: 242 EDEIMDITEGMAK--------------QVFKDALGV---DLGDFPRMPYSEAM 277
>sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1073870|pir||E64061 aspartate--tRNA ligase (EC
6.1.1.12) - Haemophilus influenzae (strain Rd KW20)
>gi|1573287|gb|AAC21981.1| (U32717) aspartyl-tRNA
synthetase (aspS) [Haemophilus influenzae Rd]
Length = 588
Score = 78.8 bits (191), Expect = 1e-13
Identities = 62/257 (24%), Positives = 118/257 (45%), Gaps = 14/257 (5%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M+ YC + G+ V L+GWV+ +G IF+ +RD GI+Q +D
Sbjct: 1 MMRTHYCGALNRNNIGQDVTLSGWVHRRRDLGGLIFIDMRDRDGIVQVCFDPKY--QDAL 58
Query: 61 ETAKKLGRESSVIVEG--IVKADER-----APGGAEVHVEKLKVIQAVSEFPIPENPEQA 113
A L E + ++G I + D + A G EV ++L++ A P+ N +
Sbjct: 59 TAAAGLRNEFCIQIKGEVIARPDNQINKNMATGEVEVLAKELRIYNASDVLPLDFN-QNN 117
Query: 114 SPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATL 173
+ E L YR+L +R P+++ ++ + + R ++ G+ ++ P+L EG
Sbjct: 118 TEEQRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLDIETPMLTKATPEGARDY 177
Query: 174 FKLKYFDKVAY--LSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLELE 230
K + L QS QL+ + + G ++ + + FR E R R EF +++E
Sbjct: 178 LVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDVE 236
Query: 231 AAWMDLWDIMKVEEELV 247
+++ ++ ++ E +V
Sbjct: 237 TSFLTAPEVREIMERMV 253
>sp|P75500|SYK_MYCPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2146330|pir||S73884 lysine--tRNA ligase (EC 6.1.1.6)
lysS - Mycoplasma pneumoniae (strain ATCC 29342)
>gi|1674257|gb|AAB96206.1| (AE000055) lysyl-tRNA
synthetase [Mycoplasma pneumoniae]
Length = 489
Score = 78.0 bits (189), Expect = 2e-13
Identities = 114/460 (24%), Positives = 200/460 (42%), Gaps = 52/460 (11%)
Query: 3 EKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGE--DVF 60
+K + EL +V L G + + ++ F+ I+D +G +Q I K E + F
Sbjct: 42 QKAFANQSDAELKQYQVILTGRIIAL----RQTFIIIQDFSGKMQLYINKKTAPELFEYF 97
Query: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLLD 120
LG + ++ G + G ++VE+L+++ + P + PE
Sbjct: 98 NNYIDLGDQ--IVATGHPMMTKT--GVLTLNVERLQIVAKCLQTPPEKWHGLTDPEARAR 153
Query: 121 YRHLHIRSPKVSAIMRVKET-LIMAAREWLLREGWHEVFPPILVTGAVEGGATL--FKLK 177
R+L + + + +K T +I A R +L G+ EV PIL AV GGA FK
Sbjct: 154 KRYLDLTYNRAQVEVFLKRTQIITAIRTFLNEAGFLEVETPILQ--AVLGGANAKPFKTH 211
Query: 178 Y--FDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWM 234
Y YL + ++ L+ I G L KV+ + FR E T H EF +E+ A
Sbjct: 212 YNALKGDFYLRIANEIALKKLIVGGLPKVYEMGRMFRNEGVDTT-HNPEFTSIEMYQANA 270
Query: 235 DLWDIMKVEEELVSYMVQ-----------RTLELRKKEIEMFRDDLTTLKNTEPPFPRIS 283
D +M + E L+ ++ + +TL+L K ++ DL + T F +
Sbjct: 271 DYAVMMDLTENLIKFVCKTLNQWSFNWNGQTLDLAKPFKKVKMVDLIC-QVTGVNFDDVK 329
Query: 284 YDE-AIEILQSKGVKIEWGDDMGADEERVLTQEFDR--------PFFVYGYPKHIKAFYM 334
D+ AI + + V+++ + +++ ++ + F++ P FV YPK +
Sbjct: 330 DDQTAIALAKQHKVELKKHEQ---NKQHIINRFFEQFCEHTLIQPTFVTHYPKAVSPL-A 385
Query: 335 KEDPNDPRKVLAADMLA-----PEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDY--EW 387
K+DP++P ++ Y E+ E+ +++ +Q K G D E
Sbjct: 386 KQDPHNPEFTERFELFINTKELANAYSELNDPLEQRARFEQQLQE-KRMGNDEASELDES 444
Query: 388 YLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPR 427
+LD +G P G G+GV+RLV + + IR FP+
Sbjct: 445 FLDALSFGLPPTGGLGIGVDRLVMLLCECSSIRDVVFFPQ 484
>sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2146065|pir||S73434 aspartate--tRNA ligase (EC
6.1.1.12) aspS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1673765|gb|AAB95756.1| (AE000013)
aspartyl-tRNA synthetase [Mycoplasma pneumoniae]
Length = 557
Score = 77.6 bits (188), Expect = 3e-13
Identities = 82/307 (26%), Positives = 135/307 (43%), Gaps = 32/307 (10%)
Query: 3 EKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFET 62
++ + ++ E K V +AGWV ++G+ F+ + D T IQ V KN E
Sbjct: 11 QRVFIGNLTSEHLNKTVTIAGWVKRIKKLGELNFVIVGDKTNTIQ-VTCKNK------EQ 63
Query: 63 AKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFP--IPENPEQASPELLLD 120
K L RE VIV+G +K R + A S+ P I E+ A E+ L
Sbjct: 64 VKYLTREDLVIVKGKLK---RLDSVRFEITNPTITLFAKSKTPPLIIEDKTDALEEVRLR 120
Query: 121 YRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKYFD 180
YR+L +R P + + ++ + +A R WL + G+ EV P L EG
Sbjct: 121 YRYLDLRRPVMQKRLALRHKVTLAVRNWLDQMGFIEVETPTLTKSTPEGARDFLVPARIR 180
Query: 181 KVAY--LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLW 237
+ ++ L QS Q+Y + + G EK + + +R E SR R E ++LE A+
Sbjct: 181 EHSFYALPQSPQIYKQLLMVGGTEKYFQIAHVYRDEDSRKDRQ-PEHTQIDLEVAF---- 235
Query: 238 DIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVK 297
+E+V ++QR +++FR L + PFP + + EA S
Sbjct: 236 ----YTKEMVMDLIQRLF------VDVFRQVLNI--KLKKPFPVLKFAEAFNRFGSDKPD 283
Query: 298 IEWGDDM 304
+ +G ++
Sbjct: 284 LRYGFEL 290
>pir||B81858 lysine--tRNA ligase (EC 6.1.1.6) NMA1638 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380280|emb|CAB84866.1| (AL162756) lysyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 503
Score = 76.9 bits (186), Expect = 4e-13
Identities = 102/448 (22%), Positives = 193/448 (42%), Gaps = 37/448 (8%)
Query: 11 KPELD--GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGR 68
K ELD G VK+AG + ++GK F I+D +G IQ + V ++V +
Sbjct: 58 KEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNKGVSQEVLDDFNHWDL 117
Query: 69 ESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP-ELLLDYRHLHIR 127
V EG + G V V ++++ S P+P+ + S E R++ +
Sbjct: 118 GDIVGAEGTLFKTNH--GELTVRVSGIRLLSK-SLRPLPDKHKGLSDQETKYRQRYVDLI 174
Query: 128 SPKVSAIMRVKET-LIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKL----KYFDKV 182
+ + S +K + +I + R +++ E + EV P++ + GGAT D
Sbjct: 175 ANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMM--HPIPGGATAKPFVTHHNALDIP 232
Query: 183 AYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMK 241
YL + +LYL+ + G LE+V+ + SFR E + RH EF +E A+ D +M+
Sbjct: 233 LYLRIAPELYLKRLVVGGLERVFEINRSFRNE-GMSVRHNPEFTMIEFYEAFSDYERMMQ 291
Query: 242 VEEELV---SYMVQRTLEL----RKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSK 294
+ E+++ S+ V T + ++ ++E + LT L+ + P + ++ + K
Sbjct: 292 MAEDIIRNASHTVNGTANITYNGKEVDLESPFERLTILEAIKKYNPHYTDEQLNDAEWLK 351
Query: 295 GVKIEWGDDMGADE----------ERVLTQEFDRPFFVYGYPKHI----KAFYMKEDPND 340
++ G+ + E + P F+ YP + +A K+ +
Sbjct: 352 KEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLARASDTKQGLTE 411
Query: 341 PRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDPKDYEW-YLDLRKYGSVPH 399
++ GY E+ ++ + + V + + Y+ Y+ ++G P
Sbjct: 412 RFELFVVGRELANGYSELNDPEDQAERFKAQVAQKDAGDDEAMHYDADYIRAMEFGLPPT 471
Query: 400 SGFGLGVERLVAWVLKLDHIRWATLFPR 427
G G+G++RLV + IR LFP+
Sbjct: 472 GGCGIGIDRLVMLLTDSQTIRDVILFPQ 499
>pir||C81086 lysyl-tRNA synthetase, heat inducible NMB1425 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226664|gb|AAF41786.1| (AE002491) lysyl-tRNA
synthetase, heat inducible [Neisseria meningitidis MC58]
Length = 503
Score = 76.1 bits (184), Expect = 7e-13
Identities = 104/451 (23%), Positives = 197/451 (43%), Gaps = 43/451 (9%)
Query: 11 KPELD--GKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGR 68
K ELD G VK+AG + ++GK F I+D +G IQ + V ++V +
Sbjct: 58 KEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNKGVSQEVLDDFNHWDL 117
Query: 69 ESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASP-ELLLDYRHLHIR 127
V EG + G V V ++++ S P+P+ + S E R++ +
Sbjct: 118 GDIVGAEGTLFKTNH--GELTVRVSGIRLLSK-SLRPLPDKHKGLSDQETKYRQRYVDLI 174
Query: 128 SPKVSAIMRVKET-LIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKL----KYFDKV 182
+ + S +K + +I + R +++ E + EV P++ + GGAT D
Sbjct: 175 ANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMM--HPIPGGATAKPFVTHHNALDIP 232
Query: 183 AYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMK 241
YL + +LYL+ + G LE+V+ + SFR E + RH EF +E A+ D +M+
Sbjct: 233 LYLRIAPELYLKRLVVGGLERVFEINRSFRNE-GMSVRHNPEFTMIEFYEAFSDYERMMQ 291
Query: 242 VEEELV---SYMVQRTLEL----RKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSK 294
+ E+++ S V T + ++ ++E + LT L+ + P + ++ + K
Sbjct: 292 MAEDIIRNASRTVNGTANITYNGKEVDLESPFERLTILEAIKKYNPHYTDEQLNDAEWLK 351
Query: 295 GVKIEWGDDMGADE----------ERVLTQEFDRPFFVYGYPKHI----KAFYMKEDPND 340
++ G+ + E + P F+ YP + +A K+ +
Sbjct: 352 KEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLARASDTKQGLTE 411
Query: 341 PRKVLAADMLAPEGYGEIIGGSEREDNYDKL-VQRIKEEGMDPKDYEW---YLDLRKYGS 396
++ GY E+ ++ ED ++ Q ++++ D + + Y+ ++G
Sbjct: 412 RFELFVVGRELANGYSEL---NDPEDQAERFKAQVVQKDAGDDEAMHYDADYIRAMEFGL 468
Query: 397 VPHSGFGLGVERLVAWVLKLDHIRWATLFPR 427
P G G+G++RLV + IR LFP+
Sbjct: 469 PPTGGCGIGIDRLVMLLTDSQTIRDVILFPQ 499
>sp|Q9KU60|SYK_VIBCH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|11271287|pir||A82296 lysyl-tRNA synthetase, heat
inducible VC0664 [imported] - Vibrio cholerae (group O1
strain N16961) >gi|9655101|gb|AAF93829.1| (AE004152)
lysyl-tRNA synthetase, heat inducible [Vibrio cholerae]
Length = 512
Score = 74.9 bits (181), Expect = 2e-12
Identities = 105/466 (22%), Positives = 202/466 (42%), Gaps = 56/466 (12%)
Query: 2 IEKTYCQDIKPELDGKR--VKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDV 59
++K + + K EL+ V +AG V + + FL I++++G IQ +K V +++
Sbjct: 56 LQKKFGEKSKEELEALNHVVSIAGRVMAK----RGPFLVIQETSGRIQAYASKEVQ-QEL 110
Query: 60 FETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPEQASPELLL 119
+ + L + V+G + + G V++E+ +++ P+PE + + +
Sbjct: 111 KDKYQGLDIGDIIGVQGALHKSGK--GDLYVNMEQFQLLTKALR-PLPEKFHGLTDQEMR 167
Query: 120 DYRHLHI-----RSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPIL--VTGAVEGGAT 172
YR ++ + + + I+R K ++ A R +++ + + EV P++ + G
Sbjct: 168 -YRQRYVDLIVNENSRNAFIVRSK--VMSAIRNFMISKQFMEVETPMMHVIPGGASARPF 224
Query: 173 LFKLKYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEA 231
+ D YL + +LYL+ + G ++V+ + +FR E + RH EF +E
Sbjct: 225 ITHHNALDMPMYLRIAPELYLKRLVVGGFDRVFEINRNFRNE-GLSPRHNPEFTMMEFYM 283
Query: 232 AWMDLWDIMKVEEELVSYMV------------QRTLELRKKEIEMFRDDLTTLKNTEPPF 279
A+ D D+M + EEL+S + + T+E K M D +K+ P
Sbjct: 284 AYADYKDLMDLTEELLSSVALEVLGSTSMPYGEHTVEFGGKYARMSMFD--AIKHYNPNH 341
Query: 280 PRI---------SYDEAIEILQSKGVKIEWGDDMGADEERVLTQEFD----RPFFVYGYP 326
+I + D + I +S V +E G E + + + +P F+ GYP
Sbjct: 342 AQIQALTEEDIQNRDLMVSIAKSVHVDVEPFWTCGQLLEEIFGETAEPKLMQPTFITGYP 401
Query: 327 KHIKAFYMKEDPN----DPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKEEGMDP 382
I + D N D + G+ E+ +++ + V+ KE G D
Sbjct: 402 ADISPLARRSDDNPFFTDRFEFFIGGREVANGFSELNDAEDQDARFKAQVEA-KESGDDE 460
Query: 383 KDY--EWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFP 426
+ Y+ ++G P +G G+G++RLV + IR LFP
Sbjct: 461 AMFYDADYITALEHGLPPTAGQGIGIDRLVMLLTNTHTIRDVILFP 506
>sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
Length = 586
Score = 74.5 bits (180), Expect = 2e-12
Identities = 70/271 (25%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
M + C ++ +L K+V++ WV GK IFL IRD Q ++ + E +
Sbjct: 1 MFKVIKCNELNEKLIDKKVEINAWVKKIRHHGKFIFLNIRDRYEKAQVLVNE----EKLL 56
Query: 61 ETAKKLGRESSVIVEGI--------VKADERAPGGAEVHVEKLKVIQAVSEFP-IPENPE 111
+ A+K+ E + ++G+ + A+ + G E+ + +++I +E P + E+
Sbjct: 57 KIAEKIKLEYCIKIQGLLIKRPPNMINANMKT-GHFEILAKNIEIISKCNELPFMIEDDN 115
Query: 112 QASPELLLDYRHLHIR--SPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEG 169
AS L+YR+L +R S K I+R + T ++ R +L++ + E+ P V EG
Sbjct: 116 NASENSKLEYRYLDLRRDSLKNKIILRCQATHLI--RNFLIKRKFLELETPTFVKSTPEG 173
Query: 170 GATLFKLKYFDKVAY--LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWH 226
K ++ L QS QLY + I G +K + + +R E SR R EF
Sbjct: 174 ARDFVIPSRIHKGSFYALPQSPQLYKQLIMIAGFDKYFQIARCYRDEDSRGDRQ-PEFTQ 232
Query: 227 LELEAAWMDLWDIMKVEEELVSYMVQRTLEL 257
L+LE +++ +I K+ E ++ + + + +
Sbjct: 233 LDLEMSFVKKENIFKLIENMLFLIFKNCINI 263
>dbj|BAA90843.1| (AB031211) LysS [Bacillus halodurans]
Length = 310
Score = 74.5 bits (180), Expect = 2e-12
Identities = 83/317 (26%), Positives = 143/317 (44%), Gaps = 61/317 (19%)
Query: 153 GWHEVFPPILVTGAVEGGATLFKL----KYFDKVAYLSQSAQLYLEAAIFG-LEKVWSLT 207
G+ EV P + ++ GGA+ D Y+ + +L+L+ I G +EKV+ +
Sbjct: 3 GYLEVETPTM--HSIPGGASARPFVTHHNALDMTLYMRIAIELHLKRLIVGGMEKVYEIG 60
Query: 208 PSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYM---VQRTLELRKKEIEM 264
FR E TR H EF +EL A+ D DIM++ E L++++ V T + E E+
Sbjct: 61 RVFRNEGVSTR-HNPEFTMIELYEAYADYNDIMELTELLIAHIAKDVLGTTTITYGEHEV 119
Query: 265 FRDDLTTLKNTEPPFPRISYDEAIEILQSKGVKIEWGDDMGADEERVLTQEFD------- 317
N EP + R+ EAI+ + +++ ++M +E R L +E +
Sbjct: 120 ---------NLEPKWRRVHMVEAIK----EETGVDFWNEMSDEEARALAKEHNVPVKETM 166
Query: 318 -------------------RPFFVYGYPKHIKAFYMKEDPNDPR-----KVLAADMLAPE 353
+P FVYG+P I K++P+DPR ++
Sbjct: 167 TYGHVVNEFFEHFVEEKLIQPTFVYGHPVAISPL-AKKNPDDPRFTDRFELFIVGREHAN 225
Query: 354 GYGEIIGGSEREDNYDK-LVQRIKEEGMDPKDY--EWYLDLRKYGSVPHSGFGLGVERLV 410
+ E+ ++ +++ LV+R E+G D E +++ +YG P G G+G++RLV
Sbjct: 226 AFSELNDPIDQRHRFEQQLVER--EQGDDEAHMMDEDFVESLEYGMPPTGGLGIGIDRLV 283
Query: 411 AWVLKLDHIRWATLFPR 427
+ IR LFP+
Sbjct: 284 MLLTNSPSIRDVLLFPQ 300
>sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|581319|emb|CAA52877.1| (X74912) putative lysyl-tRNA
synthetase [Mycoplasma hominis]
Length = 488
Score = 73.7 bits (178), Expect = 4e-12
Identities = 103/433 (23%), Positives = 185/433 (41%), Gaps = 62/433 (14%)
Query: 36 FLWIRDSTGIIQTVIAKNVVGEDVFETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKL 95
F+ ++D+ G +Q K + E +T + + V G + + A V +
Sbjct: 72 FIVLQDNCGQMQIYANKKTLNESSAKTFSLMDFGDILSVRGTLS---KTNTDALVMKAQD 128
Query: 96 KVIQAVSEFPIPE------NPEQASPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWL 149
V S P+P+ +PE+ + +D + + K ++ +I RE+
Sbjct: 129 MVTLTKSLKPLPDKFHGLVDPEERRRQRYVDL----MMNEKTRNTFVMRTQIIKGIREYF 184
Query: 150 LREGWHEVFPPILVTGAVEGGATLFKLKYF----DKVAYLSQSAQLYLEAAIFG-LEKVW 204
+ EV PIL + GGA F ++ YL + +L L+ I G L++V+
Sbjct: 185 DSLNYIEVDTPIL--NPMLGGAAAKPFITFYNATNRNFYLRIATELPLKKLIVGGLDRVY 242
Query: 205 SLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEM 264
+ FR E T H EF +E A+ DLW +M+ E + +++ + KE++
Sbjct: 243 EIGRMFRNEGVDTT-HNPEFTSIEFYEAYSDLWGMMERTEGVFKHLMNK---FNIKEVKF 298
Query: 265 FRDDLTTLKNTEPPFPRISYDEAI-----------------EILQSKGVKIE----WGDD 303
D+T PF R++ +A+ E+ + G+KIE +G
Sbjct: 299 NGFDMTF----NFPFKRVNMIDAMSEKINVDIRKLNEEQMFELAKKHGIKIEKFFRYGHI 354
Query: 304 MGADEERVLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAAD-MLAPEGYGEIIGGS 362
+ E+ + + P FVYG+P I DP+D R A+ + + + + +
Sbjct: 355 INELFEKYVEETLMEPTFVYGHPIEISPT-AAIDPDDKRFTTRAETFIGTKEFANMF--T 411
Query: 363 EREDNYDKLVQRI------KEEGMDP-KDYEW-YLDLRKYGSVPHSGFGLGVERLVAWVL 414
E D D+L QR KE G + + +W +++ +YG P G G+G++R + +
Sbjct: 412 ELNDPIDQL-QRFENQLLEKENGNEEANEIDWDFVNALEYGMPPTGGSGMGIDRTIMTLT 470
Query: 415 KLDHIRWATLFPR 427
+ D IR LFP+
Sbjct: 471 QNDSIRDVVLFPQ 483
>pir||S77851 probable aspartate--tRNA ligase (EC 6.1.1.12) - Mycoplasma
capricolum
Length = 524
Score = 73.4 bits (177), Expect = 5e-12
Identities = 75/298 (25%), Positives = 129/298 (43%), Gaps = 35/298 (11%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAK-------NVVGEDV 59
C ++ + ++V L GWV ++G +F+ ++D GI Q VI + N+ E V
Sbjct: 7 CGELTLQNVDQKVILQGWVKKIRKLGAMVFIDLKDRYGITQLVIEQENINLINNLKNEYV 66
Query: 60 FETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFP-IPENPEQASPELL 118
E S ++V+ E G EV V+ L VI P + EN + +
Sbjct: 67 IEI-------SGIVVKRKSVNKELITGEIEVIVKDLLVINKSELTPFVLENDVNVNEDTR 119
Query: 119 LDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLKY 178
L YR+L +R + + ++ + R +L + EV P EG
Sbjct: 120 LTYRYLDLRRQVMQNNLIIRAKINHIIRNYLTDLNFLEVETPYFAKSTPEGARHFLVPSR 179
Query: 179 FDKVAY--LSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMD 235
+K + L QS QL+ + I G+++ + + FR E R R EF L+LE ++
Sbjct: 180 LNKNKFYALPQSPQLFKQLLMISGIDRYYQIVRCFRDEDLRIDRQ-PEFTQLDLEMSFAT 238
Query: 236 LWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQS 293
D+M++ E L+ ++ KE++ F + P R+SY +AI++ S
Sbjct: 239 SEDVMQISESLIKKIL--------KEVKNF--------EIKEPLLRLSYKDAIDLYGS 280
>pir||T04993 probable aspartate--tRNA ligase (EC 6.1.1.12) T16L1.250 -
Arabidopsis thaliana >gi|3549678|emb|CAA20589.1|
(AL031394) putative aspartate--tRNA ligase [Arabidopsis
thaliana] >gi|7270325|emb|CAB80093.1| (AL161584)
putative aspartate--tRNA ligase [Arabidopsis thaliana]
Length = 636
Score = 69.9 bits (168), Expect = 6e-11
Identities = 79/297 (26%), Positives = 130/297 (43%), Gaps = 53/297 (17%)
Query: 7 CQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVFETAKKL 66
C ++ GKRV L GWV + G FL +RD TGI+Q + E +
Sbjct: 79 CGELSVNDVGKRVHLCGWVALHRVHGGLTFLNLRDHTGIVQVRTLPDEFPE-AHGLINDM 137
Query: 67 GRESSVIVEGIVKA-------DERAPGGAEV---HVEKLKVIQAVSEFPI---PENPEQA 113
E V+VEG V++ + G EV HVE L ++ F + EN +
Sbjct: 138 RLEYVVLVEGTVRSRPNESVNKKMKTGFVEVVAEHVEILNPVRTKLPFLVTTADENKDLI 197
Query: 114 SPELLLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATL 173
E+ L +R L +R ++ + ++ ++ R +L E H G +E G T
Sbjct: 198 KEEIRLRFRCLDLRRQQMKNNIVLRHNVVKLIRRYL--EDRH---------GFIESG-TF 245
Query: 174 FKLKYFDKVAYLSQSAQLYLE-AAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAA 232
+ L QS QL+ + + G +K + + FR E R R EF L++E A
Sbjct: 246 YA---------LPQSPQLFKQMLMVSGFDKYYQIARCFRDEDLRADRQ-PEFTQLDMEMA 295
Query: 233 WMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIE 289
+M + D++K+ E+L+ R + K I++ PFPR++Y +A++
Sbjct: 296 FMPMEDMLKLNEDLI-----RKVFSEIKGIQL-----------PDPFPRLTYADAMD 336
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.139 0.418
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 172303778
Number of Sequences: 2977
Number of extensions: 7517288
Number of successful extensions: 18310
Number of sequences better than 1.0e-10: 143
Number of HSP's better than 0.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 17823
Number of HSP's gapped (non-prelim): 188
length of query: 434
length of database: 189,106,746
effective HSP length: 54
effective length of query: 380
effective length of database: 156,788,448
effective search space: 59579610240
effective search space used: 59579610240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)