BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2211 (bmr-like) DE:Multidrug resistance protein (384 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||G75210 multidrug resistance protein PAB2211 - Pyrococcus ab... 754 0.0 pir||G71246 hypothetical protein PH0230 - Pyrococcus horikoshii ... 645 0.0 gb|AAK43250.1| Permease, putative [Sulfolobus solfataricus] 139 4e-32 dbj|BAB07201.1| (AP001518) multidrug-efflux transporter [Bacillu... 113 3e-24 gb|AAK42050.1| Multidrug-efflux transporter [Sulfolobus solfatar... 103 3e-21 pir||F72774 hypothetical protein APE0184 - Aeropyrum pernix (str... 101 2e-20 emb|CAC12313.1| (AL445066) multidrug resistance protein NorA rel... 100 4e-20 pir||C75537 conserved hypothetical protein - Deinococcus radiodu... 99 8e-20 gb|AAK42813.1| Permease, major facilitator superfamily [Sulfolob... 94 3e-18 emb|CAC12498.1| (AL445067) sugar transporter related protein [Th... 85 2e-15 emb|CAC12197.1| (AL445066) multidrug resistance protein related ... 75 1e-12 >pir||G75210 multidrug resistance protein PAB2211 - Pyrococcus abyssi (strain Orsay) >gi|5457643|emb|CAB49134.1| (AJ248283) Multidrug resistance protein [Pyrococcus abyssi] Length = 384 Score = 754 bits (1926), Expect = 0.0 Identities = 384/384 (100%), Positives = 384/384 (100%) Query: 1 MERDAKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQ 60 MERDAKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQ Sbjct: 1 MERDAKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQ 60 Query: 61 ISLRIGYKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINMGLRDPNYSALLSEKV 120 ISLRIGYKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINMGLRDPNYSALLSEKV Sbjct: 61 ISLRIGYKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINMGLRDPNYSALLSEKV 120 Query: 121 KSEEERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQFLVV 180 KSEEERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQFLVV Sbjct: 121 KSEEERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQFLVV 180 Query: 181 IPALMLVKDVPVKESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRFGRDI 240 IPALMLVKDVPVKESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRFGRDI Sbjct: 181 IPALMLVKDVPVKESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRFGRDI 240 Query: 241 KEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFILASIV 300 KEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFILASIV Sbjct: 241 KEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFILASIV 300 Query: 301 YVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLFAVSLSY 360 YVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLFAVSLSY Sbjct: 301 YVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLFAVSLSY 360 Query: 361 PFYATAILYIFATAMFYAFFIKHN 384 PFYATAILYIFATAMFYAFFIKHN Sbjct: 361 PFYATAILYIFATAMFYAFFIKHN 384 >pir||G71246 hypothetical protein PH0230 - Pyrococcus horikoshii >gi|3256619|dbj|BAA29302.1| (AP000001) 385aa long hypothetical protein [Pyrococcus horikoshii] Length = 385 Score = 645 bits (1646), Expect = 0.0 Identities = 310/384 (80%), Positives = 352/384 (90%) Query: 1 MERDAKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQ 60 ME+DAKVLVIA AVGQLFLQFSWF+MPFYLK LGY M+KMG+LFS QT IGG+SFLLAGQ Sbjct: 1 MEKDAKVLVIATAVGQLFLQFSWFIMPFYLKALGYDMNKMGILFSTQTLIGGISFLLAGQ 60 Query: 61 ISLRIGYKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINMGLRDPNYSALLSEKV 120 +SL+ GYK+TLILAA +G LGRI QV+ YNF +L+LGFFLVG+NMGLRDPNYSALLSEKV Sbjct: 61 LSLKFGYKKTLILAAGMGALGRIFQVLAYNFEMLLLGFFLVGVNMGLRDPNYSALLSEKV 120 Query: 121 KSEEERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQFLVV 180 K+EEERHRIFSYSFGLGTLMNA+GVLVAGY PG+L+SLGY + +AY+LVIALAL+QF +V Sbjct: 121 KNEEERHRIFSYSFGLGTLMNALGVLVAGYLPGHLVSLGYSERLAYKLVIALALIQFAIV 180 Query: 181 IPALMLVKDVPVKESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRFGRDI 240 PAL+++KDVPV S+IKWRK+LI++ILKFSLPSA+IGLGAGITIPYMSIYFNLRFGRDI Sbjct: 181 FPALIVIKDVPVTTSKIKWRKELIIKILKFSLPSALIGLGAGITIPYMSIYFNLRFGRDI 240 Query: 241 KEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFILASIV 300 +EISWVFF Q++VMGLGSFILP L+ ++G VKVITYFQ SAA LFLIFPS+PTF +AS V Sbjct: 241 REISWVFFSQEVVMGLGSFILPALINRLGPVKVITYFQGSAAFLFLIFPSLPTFAIASFV 300 Query: 301 YVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLFAVSLSY 360 Y+IRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRG GNYIGG LFA+SL+Y Sbjct: 301 YIIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGLGNYIGGALFAISLAY 360 Query: 361 PFYATAILYIFATAMFYAFFIKHN 384 PFY TAI YI AT MFYAFFIK+N Sbjct: 361 PFYTTAIFYIIATTMFYAFFIKYN 384 >gb|AAK43250.1| Permease, putative [Sulfolobus solfataricus] Length = 359 Score = 139 bits (348), Expect = 4e-32 Identities = 105/387 (27%), Positives = 185/387 (47%), Gaps = 40/387 (10%) Query: 1 MERDAKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQ 60 M+ + +LV+A++VG + + +M YLK LG +GV+ + L L Sbjct: 1 MKSEDFLLVLASSVGGIVWGANTVIMALYLKSLGLNPLTIGVILGSAIIVNTLLSLFWAV 60 Query: 61 ISLRIGYKRTLILAALLGLLGRILQVIGYNFYILI-LGFFLVGINMGLRDPNYSALLSEK 119 + G K+ + ++ +G L +L +I Y+ I G+ L+ S++L+EK Sbjct: 61 LGDAYGRKKFVYISRGVGGLSFLLLLITPYAYLFINQGYGLI-----------SSILAEK 109 Query: 120 VKSEEERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQFLV 179 + + +Y L T+ + +G L+ I L YR IA ++ L L+ Sbjct: 110 ---SGDLDKAMAYRSSLNTIFSVVGSLLP-------IVLNYRSIIAVDSIVTFLSLLLLI 159 Query: 180 VIPALMLVKDVPVKESRIKWRKDLIVRILKFSL-----PSAIIGLGAGITIPYMSIYFNL 234 PVKE+ RK + ++I F + AIIGLGAG+ +P +S++FNL Sbjct: 160 -----------PVKENYRGTRK-VTLKISSFKVLGKLSTEAIIGLGAGVLLPMLSLWFNL 207 Query: 235 RFGRDIKEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTF 294 RF +S ++ ++ + LG+ P L + +G ++ I ++A L I P + Sbjct: 208 RFHATASSLSPIYAISEITLALGTLTSPFLAKTLGRIRAIVITHFAAIALLFIMPFSTSL 267 Query: 295 ILASIVYVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLF 354 +A ++YV+R++LMN P+ +S + EE++ + + R G + G LF Sbjct: 268 FIAGVIYVMRNVLMNSTGPLMNSLVFKVVKEEERSRVNSMLQLLDAIPRSLGPNLTGYLF 327 Query: 355 AV-SLSYPFYATAILYIFATAMFYAFF 380 + +L+ PF+ T LY+ AT +FY FF Sbjct: 328 YIGNLNVPFFITGSLYLVATILFYNFF 354 >dbj|BAB07201.1| (AP001518) multidrug-efflux transporter [Bacillus halodurans] Length = 413 Score = 113 bits (281), Expect = 3e-24 Identities = 95/399 (23%), Positives = 174/399 (42%), Gaps = 19/399 (4%) Query: 3 RDAKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQIS 62 R+ + +++ + + L + +Y++ LGY G + ++Q ++ L AG IS Sbjct: 17 RNVRHFFLSSLLSNIGLGIFMVIYNYYIRELGYDEQVNGRVIAMQAMATAIALLPAGFIS 76 Query: 63 LRIGYKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINMGLRDPNYSALLSEKVKS 122 + G K+ + + ALL + +L+ I +L++ F+ G + + LL+E S Sbjct: 77 DQKGRKKMIFIGALLTAISLLLRSIFAGESLLLMTAFMTGFFLAFIQVSAIPLLAEN-SS 135 Query: 123 EEERHRIFSYSFGLGTLMNAIGVLVAGY---APGYLISLGYRKEIAYRLVIALALLQFLV 179 E+ER +FS++F L + N IG L+ G A L + + L+I A F Sbjct: 136 EKERVHLFSFNFALIMIANVIGNLLGGILTDAWNVLWGVSMLSSVRLTLLIGTACF-FAA 194 Query: 180 VIPALMLVKDVPVKESR---------IKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSI 230 + P L + + +R +K + + I F++ + +IG G+G+ IPY+++ Sbjct: 195 LWPVLQIEERSKQANARHEDTSLIQQMKQHRSSLKLIGLFAIANVLIGFGSGLVIPYLNL 254 Query: 231 YFNLRFGRDIKEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPS 290 YF RF + V Q + + + P + K G V+ + Y Q ++ L+ Sbjct: 255 YFTDRFDMSTSLVGIVLSMGQAMTAIALMVGPMVAHKYGEVRAVVYLQLASLPFLLVAAF 314 Query: 291 IPTFILASIVYVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGI-RRAFSTFMRGAGNYI 349 LA + ++ R LMN P+ + MM K A + + F G Sbjct: 315 TMNPWLAVLAFLFRQALMNAGNPIQMALMMRSVHPAMKGLANSVGQMVFQLGWAVMGPVS 374 Query: 350 GGLLFA----VSLSYPFYATAILYIFATAMFYAFFIKHN 384 G++ + F TAILY+ +A F+ F + N Sbjct: 375 AGIVVVYGPYTGYAIAFSMTAILYLIGSAYFFLVFRRVN 413 >gb|AAK42050.1| Multidrug-efflux transporter [Sulfolobus solfataricus] Length = 398 Score = 103 bits (255), Expect = 3e-21 Identities = 97/385 (25%), Positives = 168/385 (43%), Gaps = 28/385 (7%) Query: 8 LVIANAVGQLFLQFSWFVMPFYLKV-LGYGMDKMGVLFSVQTFIGGLSFLLAGQISLRIG 66 L I+ + L + ++P+ + V L Y +G +++V TF + L G ++ G Sbjct: 9 LTISRILRSLSAGIIFVILPYLVLVELKYSSLILGFIYTVGTFATAILGLAVGYLADLYG 68 Query: 67 YKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINM----------GLRDPNYSALL 116 K +LIL +L L +L I ++ L + L G + G+ P +AL+ Sbjct: 69 RKNSLILVSLFLPLSVLLIFINHSLIALFIASALGGYSATGAVAGGGIGGIVAPIQNALI 128 Query: 117 SEKVKSEEERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQ 176 +E + E+R FS L + +IG LVAG+ + + + I L L Sbjct: 129 TE-LTDNEDRTFYFSLFTFLSGISASIGSLVAGF---------FTSKQGFLFAIILGFLS 178 Query: 177 FLVVIPALMLVKDVPVKESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRF 236 L + P + K++ + + +K + V I KFS+ + G+ G+ P++ YF + + Sbjct: 179 VLALFP--IRAKNIKARSASLKSK----VVIGKFSITGLLNGISVGLITPFLIPYFIIVY 232 Query: 237 GRDIKEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFIL 296 E+S F L+ + P L +KIG +K I + ALL +I P I F + Sbjct: 233 HTPKSEMSIYTFLSSLIASTIILLAPVLDKKIGFLKSIAITRGIGALLSIIMPLIRVFPI 292 Query: 297 ASIVYVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLFAV 356 + +Y+I + + P+ M S +E A GI + + G LF+ Sbjct: 293 SLGIYLILPGMRVLALPIQQRAMTEMVSQDEVGRAMGINQVTRLAASSGSTGLTGYLFSE 352 Query: 357 S-LSYPFYATAILYIFATAMFYAFF 380 S + PF A+ I+ M+Y FF Sbjct: 353 SQIDVPFLASGIIMALNIYMYYKFF 377 >pir||F72774 hypothetical protein APE0184 - Aeropyrum pernix (strain K1) >gi|5103575|dbj|BAA79096.1| (AP000058) 412aa long hypothetical protein [Aeropyrum pernix] Length = 412 Score = 101 bits (249), Expect = 2e-20 Identities = 95/385 (24%), Positives = 174/385 (44%), Gaps = 16/385 (4%) Query: 5 AKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQISLR 64 A +LV+A G F + P Y+ G+ + G+L S T + LL+G +S Sbjct: 3 APLLVLAALNGLSFGVIVTVLAP-YMYSAGFSGTEWGLLTSTATVTSIIFTLLSGPLSDA 61 Query: 65 IGYKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINMGLRDPNYSALLSEKVKSEE 124 +G +R + ++ L + + + GF L G++MG+ +AL++ + +E Sbjct: 62 LGARRVVAAGYIVKAASFTLLAVPSTVF-MAAGFTLSGVSMGISWSATTALVARSGR-DE 119 Query: 125 ERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEI-AYRLVIALALLQFLVVIPA 183 HR F++ + A+G L+ G P L S+ + AYR I L L+ Sbjct: 120 MLHRSFTFFMASNMVGGALGSLM-GVIPPLLSSITSLTLLEAYRATILLVAPLSLLQAGI 178 Query: 184 LMLVKDVPVKESRIKWRKDLIVRILKFSLP----------SAIIGLGAGITIPYMSIYFN 233 + V++ E R ++R + ++ + +IGLGA ++I ++ YF Sbjct: 179 ALAVREEVSAEGRASIGPGELLRGFREAVSDRRFRLLILFNMVIGLGASMSIHNIAYYFA 238 Query: 234 LRFGRDIKEISWVFFGQQLVMGLGSFILPELVRKIGA-VKVITYFQWSAALLFLIFPSIP 292 ++G EI V +Q+ M L + + ++G+ +KV + L + + Sbjct: 239 AKYGVTSAEIGVVNALEQVSMALVAVGASRIAERVGSTLKVYIALTSLSVPLLVAMTLVD 298 Query: 293 TFILASIVYVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGL 352 ++++A+ +YV+R++LMN P+ ++ M E + +A+ I T AG IGG Sbjct: 299 SYVVAAAIYVVRTVLMNAANPLLEALTMRVVPRERRGSASSILSLSFTLPATAGRAIGGA 358 Query: 353 LFAVSLSYPFYATAILYIFATAMFY 377 L ++L P TA +Y A A Y Sbjct: 359 LLDINLELPLRLTAAIYTLALAHLY 383 >emb|CAC12313.1| (AL445066) multidrug resistance protein NorA related protein [Thermoplasma acidophilum] Length = 362 Score = 100 bits (246), Expect = 4e-20 Identities = 87/364 (23%), Positives = 162/364 (43%), Gaps = 19/364 (5%) Query: 26 MPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQISLRIGYKRTLILAALLGLLGRILQ 85 M YL +GY + +GV+ I + ++ G K LI+ L+ + Sbjct: 1 MSLYLHHIGYSLFTVGVILGSAIVISSILTFFMAMLADHYGRKSLLIVLYLIFAVSAFGF 60 Query: 86 VIGYNFYILILGFFLVGINMGLRDP-----NYSALLSEKVKSEEERHRIFSYSFGLGTLM 140 ++ +ILIL L P + A+ + + E++R +S L T Sbjct: 61 LVSKEMFILILLSGLGSFTGSGGGPIGSGGAFGAVQTALITEFTEKNR---FSRVLSTA- 116 Query: 141 NAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQFLVVIPALMLVKDVPVKESR---- 196 +A+G+L A A +LI + R + LA + +V + + + D ++ + Sbjct: 117 SAVGLL-ASSAGSFLIDVVERIGGDVYRLFYLAGIMGIVGMLITVFLNDNGIRSRKLLPS 175 Query: 197 IKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRFGRDIKEISWVFFGQQLVMGL 256 I W+K +++ S+P+ G+GAG P S++F+LRFG EI +F + + + Sbjct: 176 ISWKK-----MIRLSIPTIPNGIGAGFVSPIFSLWFHLRFGISSGEIGVIFGISNIFVLI 230 Query: 257 GSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFILASIVYVIRSILMNIVWPVND 316 ++P ++R + I + + ++++L + IP +A++VY++R L PV Sbjct: 231 FMIVIPRIIRSESELNAIVWTRAASSMLLVALAFIPFLQIAALVYILRQGLQMGAVPVRQ 290 Query: 317 SFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLFAVSLSYPFYATAILYIFATAMF 376 SF MG + E+ATA+G+ T + G L ++S YP I+ ++ Sbjct: 291 SFSMGIVDSTERATASGVTSMTRTGFSAVSPPLAGDLLSISSIYPPLIGGIITAADPLLY 350 Query: 377 YAFF 380 Y F Sbjct: 351 YMLF 354 >pir||C75537 conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6457962|gb|AAF09871.1|AE001890_3 (AE001890) conserved hypothetical protein [Deinococcus radiodurans] Length = 406 Score = 99.1 bits (243), Expect = 8e-20 Identities = 90/371 (24%), Positives = 156/371 (41%), Gaps = 20/371 (5%) Query: 21 FSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQISLRIGYKRTLILAALLGLL 80 F + FYL+ LG G L ++ L A ++ RI TL + A L +L Sbjct: 25 FMMLFLNFYLRALGLDPAWQGFLNALPALTLAALSLPAVALARRISNAHTLKVGAALSML 84 Query: 81 GRILQVIGYNFYILILGFFLVGINMGLRDPNYSALLSEKVKSEEERHRIFSYSFGLGTLM 140 G +L + + ++I+G + G L + ++ E+ R +FS L T Sbjct: 85 GTLLMALAHGPVLVIVGGLIQGAGSALSVVAGAPFMANN-SDEKSRVALFSVQSALMTGA 143 Query: 141 NAIGVLVAGYAPGYLISLGYRKEI---AYRLVIALAL-LQFLVVIPALMLV---KDVPVK 193 +G L+ G P + + A R+ + +A LQ L ++P L L K P Sbjct: 144 GFLGNLLGGRVPELYAAATHTLPSSLGALRVALLVAAGLQLLGLLPVLFLRPSGKTRPAG 203 Query: 194 ESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRFGRDIKEISWVFFGQQLV 253 S K + R++ P+ ++GLGAG TIP++++Y RF D + +F L Sbjct: 204 RSLAVRDKATMARLV---FPNVLVGLGAGATIPFLNVYIEGRFHVDYASLGSLFAWTSLA 260 Query: 254 MGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFILASIVYVIRSILMNIVWP 313 L S + P LVR++G + + Q S+ + P + ++ R LMN P Sbjct: 261 TALTSLVQPLLVRRLGQLPTVLAVQVSSLPFLALLGFAPQLWMVTVAMFTRGALMNAAGP 320 Query: 314 VNDSFMMGFFSTEEKATAAGIRR-------AFSTFMRGAGNYIGGLLFAVSLSYPFYATA 366 V ++ M E++ + + A S+ + G G L F+++ + F T Sbjct: 321 VYSAYAMTVLPEEDRPMYSAVNTMAWDLGWALSSMLSGVVR--GALDFSLAFNVLFGWTL 378 Query: 367 ILYIFATAMFY 377 ++Y + Y Sbjct: 379 LMYAASVLAIY 389 >gb|AAK42813.1| Permease, major facilitator superfamily [Sulfolobus solfataricus] Length = 391 Score = 94.0 bits (230), Expect = 3e-18 Identities = 93/372 (25%), Positives = 161/372 (43%), Gaps = 30/372 (8%) Query: 10 IANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQISLRIGYKR 69 I ++G +++ S YL +G + +G++F L G I RIGYK+ Sbjct: 15 ILRSIGIIYITLS---SSLYLSAIGVKPEIIGIIFLGAIGFSSTLNLALGIIGDRIGYKK 71 Query: 70 TLILAALLGLLGRILQVIGYNFYILILGFFLVGIN------MGLRDPNYSALLSEKVKSE 123 LI +L + +L + N ++ + G+ G+ P +AL++ E Sbjct: 72 VLIFVEILAAIASMLLALSINQTLIFAALIIGGVGGAAGGIRGVFSPGLTALVASNWSEE 131 Query: 124 EERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIA-----YRLVIALALLQFL 178 +ER R S+ +L AG L+S+ R I+ YRL+ L+ L Sbjct: 132 KERVRRLSFLMSASSL--------AGIGGSVLLSI--RSYISNSVEGYRLLYFLSFALLL 181 Query: 179 VVIPALMLVKDV--PVKESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRF 236 +L+LVK+V P K S++ +K + I K + ++I G G GI IP + +++ L F Sbjct: 182 ASAISLLLVKEVKRPKKTSKVM-KKSSMKYISKVIVSNSITGFGLGIAIPLLPLWYKLAF 240 Query: 237 GRDIKEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPSIPTFIL 296 + EI +F L +GS + +++ V IT L+ + F P L Sbjct: 241 HANSFEIGLIFTISYLTTAIGSLLSNKIMFDPLKVASITRILNGVFLIAMAFS--PWLAL 298 Query: 297 ASIVYVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLLFAV 356 A+ +Y+ R + I P + + S E+ TA+ + +T + + I G L + Sbjct: 299 AAGLYIARGLNAGIGAPNRSAVNVRGVSAEDFGTASSF-QGLATRLSQMSSGISGYLLDI 357 Query: 357 SLSYPFYATAIL 368 S S P +L Sbjct: 358 SYSLPLEIGGLL 369 >emb|CAC12498.1| (AL445067) sugar transporter related protein [Thermoplasma acidophilum] Length = 381 Score = 84.7 bits (206), Expect = 2e-15 Identities = 80/393 (20%), Positives = 163/393 (41%), Gaps = 27/393 (6%) Query: 1 MERDAKVLVIANAVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLAGQ 60 M R +L I+ A+ ++P+YL LG + ++ V G + LL Sbjct: 1 MHRYTFMLTISKAIRSFIFAAMAIIVPYYLSSLGLNAVETSLVIFVSLVSGAVFILLYPY 60 Query: 61 ISLRIGYKRTLILAALLGLLGRILQVIGYNFYILILGFFLVGINMGLRD-----PNYSAL 115 + +++ K +IL + L L ++ +I ++ Y+ + F+ GI++ RD P Sbjct: 61 VRMKL--KAKMILLSALMALAFVILIITHSVYVFVAAIFIGGISLTGRDFSAYQPVEQYA 118 Query: 116 LSEKVKSEEERHRIFSY----SFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIA 171 +S + ++ ++ FS S+G + + L Y Y+ + +++ Sbjct: 119 ISRYEQEQKAKNSAFSIYNFGSYGSAAVASLFLFLYVHYVFTYI----------FIVLLV 168 Query: 172 LALLQFLVVIPALMLVKDVPVKESRIKWRKDLIVRILKFSLPSAIIGLGAG-ITIPYMSI 230 L+LLQ + + + P +RI +D+ + S A+ G G +T +++ Sbjct: 169 LSLLQLAMYLAISFPEYNRPSAANRIP--QDVRRHVSTLSALFAVDAFGGGFVTTSMLTL 226 Query: 231 YFNLRFGRDIKEISWVFFGQQLVMGLGSFILPELVRKIGAVKVITYFQWSAALLFLIFPS 290 +F + + + ++F +V + I + KIG ++ + Y + + ++ P Sbjct: 227 WFKVVYHISLGYAGFIFIIVNIVTAISILISSHISGKIGLIRTMVYTHVISNVSLILMPV 286 Query: 291 IPTFILASIVYVIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIG 350 IP I + + +R + P DSF + + + + T + +G IG Sbjct: 287 IPNLIASQVFLYLRQTTSQMDVPARDSFTNTIIPPDYRVNSNSVFTTVRTIGQVSGPAIG 346 Query: 351 GLLFAV---SLSYPFYATAILYIFATAMFYAFF 380 G L SL Y AT I+Y + + Y +F Sbjct: 347 GFLIDAMPPSLLYVAGATKIIYDISLYIKYHWF 379 >emb|CAC12197.1| (AL445066) multidrug resistance protein related protein [Thermoplasma acidophilum] Length = 382 Score = 74.9 bits (181), Expect = 1e-12 Identities = 73/352 (20%), Positives = 155/352 (43%), Gaps = 19/352 (5%) Query: 13 AVGQLFLQFSWFVMPFYLKVLGYGMDKMGVLFSVQTFIGGLSFLLA-GQISLRIGYKRTL 71 + G +F+ S +P YL + + +G+++ V T + +S +A G + RIGYK +L Sbjct: 10 SAGLIFMALS---LPLYLLLNRISIVNVGIIY-VGTALANVSVTIAIGMLGDRIGYKYSL 65 Query: 72 ILAALLGLLGRILQVIGYNFYILILGFFL---VGINMGLRDP------NYSALLSEKVKS 122 + + LL + + ++++ + G G+R Y A + ++ Sbjct: 66 VFGEIPALLASGILAFTRSVPLIVIATVISGSAGAPGGMRGSFSVGITPYLARIWQEPSI 125 Query: 123 EEERHRIFSYSFGLGTLMNAIGVLVAGYAPGYLISLGYRKEIAYRLVIALALLQFLVVIP 182 ER ++ + ++ ++ + + G+ LG EI Y + L LL F + Sbjct: 126 RIERMAQITFVASIASIGGSLLLYLHGFITRIYGDLG-AFEILYHVAFILILLSF---VS 181 Query: 183 ALMLVKDVPVKESRIKWRKDLIVRILKFSLPSAIIGLGAGITIPYMSIYFNLRFGRDIKE 242 M+ +D K++ RK+ + + + + I G G ++ +S +F +R+G + Sbjct: 182 LTMIRRDRRQKKTTKFLRKETMKFSARVIITNVINGSAIGFSMALISAWFEIRYGVSASK 241 Query: 243 ISWVFFGQQLVMGLGSFILPEL-VRKIGAVKVITYFQWSAALLFLIFPSIPTFILASIVY 301 I VF + +GS + + + + AV + + +L + + P FI+ S +Y Sbjct: 242 IGLVFTISYITTAIGSLLASRIHISRERAVYFGSLTRILQGILLIAMAASPIFIMGSTIY 301 Query: 302 VIRSILMNIVWPVNDSFMMGFFSTEEKATAAGIRRAFSTFMRGAGNYIGGLL 353 ++R+++ P+ + + E+ TA+ I+ A S M+ G L+ Sbjct: 302 IVRTVVAGFGTPIRNVVNIQGIKDEDLGTASSIQGAPSRIMQSTSGIAGYLM 353 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.332 0.148 0.438 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 131164944 Number of Sequences: 2977 Number of extensions: 5406774 Number of successful extensions: 16070 Number of sequences better than 1.0e-10: 11 Number of HSP's better than 0.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 16038 Number of HSP's gapped (non-prelim): 11 length of query: 384 length of database: 189,106,746 effective HSP length: 51 effective length of query: 333 effective length of database: 158,583,909 effective search space: 52808441697 effective search space used: 52808441697 T: 11 A: 40 X1: 15 ( 7.2 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.9 bits) S2: 166 (69.1 bits)