BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2227 (PAB2227) DE:AMINOTRANSFERASE
(410 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75208 probable valine--pyruvate transaminase (EC 2.6.1.66)... 825 0.0
pir||E71243 probable valine--pyruvate transaminase (EC 2.6.1.66)... 740 0.0
dbj|BAA86884.1| (AB027131) multiple substrate aminotransferase (... 610 e-173
emb|CAC12318.1| (AL445066) aspartate aminotransferase related pr... 416 e-115
pir||S75385 probable valine--pyruvate transaminase (EC 2.6.1.66)... 400 e-110
gb|AAK40460.1| Aspartate aminotransferase (aspB-1) [Sulfolobus s... 400 e-110
pir||H72293 probable valine--pyruvate transaminase (EC 2.6.1.66)... 344 1e-93
pir||E75378 probable valine--pyruvate transaminase (EC 2.6.1.66)... 337 1e-91
pir||F72772 probable valine--pyruvate transaminase (EC 2.6.1.66)... 330 2e-89
dbj|BAB04846.1| (AP001511) aminotransferase [Bacillus halodurans] 309 4e-83
pir||T36254 probable valine--pyruvate transaminase (EC 2.6.1.66)... 296 4e-79
pir||H83438 probable aminotransferase PA1654 [imported] - Pseudo... 266 4e-70
pir||T47022 hypothetical protein [imported] - Yersinia pestis >g... 228 7e-59
pir||B69780 transcription regulator GntR family homolog ydfD - B... 226 4e-58
pir||G75446 probable valine--pyruvate transaminase (EC 2.6.1.66)... 216 4e-55
gb|AAK43337.1| Aspartate aminotransferase (aspB-4) [Sulfolobus s... 208 9e-53
gi|7705897 L-kynurenine/alpha-aminoadipate aminotransferase [Hom... 208 1e-52
pir||E83130 conserved hypothetical protein PA4132 [imported] - P... 206 5e-52
gi|8393641 kynurenine aminotransferase II [Rattus norvegicus] >g... 206 5e-52
pir||E83392 probable transcription regulator PA2032 [imported] -... 206 5e-52
dbj|BAB04151.1| (AP001508) transcriptional regulator (GntR famil... 202 5e-51
gi|6754408 kynurenine aminotransferase II [Mus musculus] >gi|510... 190 2e-47
pir||H83282 probable transcriptional regulator PA2897 [imported]... 190 3e-47
pir||T44350 hypothetical protein [imported] - Clostridium histol... 187 3e-46
pir||G82405 transcription regulator GntR family VCA0871 [importe... 184 1e-45
sp|P39389|YJIR_ECOLI HYPOTHETICAL 53.0 KD PROTEIN IN IADA-MCRD I... 178 1e-43
pir||T46999 hypothetical protein [imported] - Yersinia pestis >g... 176 4e-43
pir||F83124 probable transcription regulator PA4165 [imported] -... 173 3e-42
pir||B64896 hypothetical protein b1439 - Escherichia coli >gi|17... 168 1e-40
gi|11435943 L-kynurenine/alpha-aminoadipate aminotransferase [Ho... 166 4e-40
gb|AAF42764.1|AF128839_8 (AF128839) unknown [Salmonella enteriti... 165 7e-40
pir||T39678 probable valine--pyruvate transaminase (EC 2.6.1.66)... 165 1e-39
pir||T41409 probable valine--pyruvate transaminase (EC 2.6.1.66)... 163 3e-39
gi|6321236 aromatic amino acid aminotransferase; Aro8p [Saccharo... 163 4e-39
pir||T38905 probable valine--pyruvate transaminase (EC 2.6.1.66)... 157 2e-37
dbj|BAB05659.1| (AP001513) transcriptional regulator (GntR famil... 157 2e-37
gb|AAF50113.1| (AE003546) CG6321 gene product [Drosophila melano... 156 5e-37
pir||F69778 transcription regulator GntR family homolog ydeL - B... 156 5e-37
pir||F69838 opine aminotransferase homolog yisW - Bacillus subti... 153 2e-36
pir||T36319 probable aminotransferase - Streptomyces coelicolor ... 152 7e-36
pir||D83611 probable transcription regulator PA0268 [imported] -... 152 7e-36
pir||T30600 probable transaminase (EC 2.6.1.-) PCZA361.25 [simil... 151 1e-35
pir||E82968 probable transcription regulator PA5431 [imported] -... 150 4e-35
dbj|BAB12271.1| (AB047854) orf 2 [Acinetobacter sp. M-1] 148 8e-35
sp|P49309|MOCR_RHIME PROBABLE RHIZOPINE CATABOLISM REGULATORY PR... 147 2e-34
gb|AAC31185.1| (AF076240) putative regulatory protein MocR [Rhiz... 146 4e-34
dbj|BAB04297.1| (AP001509) transcriptional regulator (GntR famil... 146 4e-34
pir||G82984 probable transcription regulator PA5283 [imported] -... 141 2e-32
dbj|BAB06414.1| (AP001516) transcriptional regulator (GntR famil... 138 1e-31
sp|Q08792|YCXD_BACSU HYPOTHETICAL 50.8 KD PROTEIN IN SRFA4-SFP I... 136 5e-31
pir||G72655 aspartate transaminase (EC 2.6.1.1) APE0674 [similar... 136 6e-31
pir||G69825 transcription regulator GntR family homolog yhdI - B... 129 6e-29
emb|CAB99169.1| (AL390188) putative gntR-family regulatory prote... 127 2e-28
pir||D75469 probable regulatory protein MocR - Deinococcus radio... 126 4e-28
gb|AAF13752.1|AF117351_9 (AF117351) putative regulatory protein ... 126 4e-28
gi|11499215 aspartate aminotransferase (aspB-3) [Archaeoglobus f... 126 5e-28
pir||A75353 mocR protein - Deinococcus radiodurans (strain R1) >... 124 2e-27
gi|6321929 aromatic amino acid aminotransferase II; Aro9p [Sacch... 123 3e-27
sp|P38840|ARO9_YEAST AROMATIC AMINO ACID AMINOTRANSFERASE II >gi... 123 3e-27
pir||C33496 hisC homolog - Bacillus subtilis 123 4e-27
sp|Q60317|AAT1_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 1 (TRAN... 122 6e-27
gb|AAD04762.1| (U95370) unknown protein [Bacillus licheniformis] 122 1e-26
pir||T36822 probable transcription regulator - Streptomyces coel... 120 4e-26
gb|AAK41178.1| Aspartate aminotransferase (aspB-2) [Sulfolobus s... 120 4e-26
sp|P14909|AAT_SULSO ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 120 4e-26
pir||S45613 aspartate aminotransferase - Sulfolobus solfataricus 120 4e-26
pir||E71009 probable aromatic-amino-acid transaminase (EC 2.6.1.... 119 5e-26
pir||C69672 probable aspartate transaminase (EC 2.6.1.-) patA [s... 118 1e-25
pir||E71125 probable aromatic-amino-acid transaminase (EC 2.6.1.... 118 1e-25
sp|P16524|PATA_BACSU PUTATIVE AMINOTRANSFERASE A >gi|2632221|emb... 117 3e-25
pir||G75037 probable aromatic-amino-acid transaminase (EC 2.6.1.... 116 3e-25
emb|CAB89055.1| (AL353872) putative gntR-family regulator [Strep... 115 1e-24
pir||B75122 probable aromatic-amino-acid transaminase (EC 2.6.1.... 111 1e-23
gb|AAF01064.1|AF189258_3 (AF189258) transcriptional regulator [S... 111 1e-23
gb|AAF06954.1|AF146529_1 (AF146529) aromatic amino acid aminotra... 111 2e-23
pir||F81432 probable transaminase (EC 2.6.1.-) Cj0150c [similari... 110 3e-23
gb|AAG02195.1|AF286159_1 (AF286159) PdxR [Streptomyces venezuelae] 110 3e-23
dbj|BAB04779.1| (AP001510) aspartate aminotransferase [Bacillus ... 109 6e-23
pir||E70338 probable aspartate transaminase (EC 2.6.1.1) aspC3 [... 109 7e-23
sp|O33822|AAT_THEAQ ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 107 2e-22
gi|11499943 aspartate aminotransferase (aspB-1) [Archaeoglobus f... 107 2e-22
emb|CAB61674.1| (AL133213) putative GntR-family regulatory prot... 107 2e-22
pir||F83024 aspartate transaminase PA4976 [imported] - Pseudomon... 106 4e-22
pir||D70479 probable transaminase (EC 2.6.1.-) aspC2 [similarity... 106 6e-22
sp|Q56232|AAT_THETH ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 105 1e-21
pdb|1BJW|A Chain A, Aspartate Aminotransferase From Thermus Ther... 105 1e-21
pir||G69119 probable aspartate transaminase (EC 2.6.1.1) MTH1894... 103 3e-21
pir||B70325 probable transaminase (EC 2.6.1.-) aspC4 [similarity... 103 3e-21
gb|AAB81842.1| (AF025665) aspartate aminotransferase [Thermus aq... 103 4e-21
gi|6321000 Yer152cp [Saccharomyces cerevisiae] >gi|731527|sp|P10... 101 1e-20
pir||D71003 probable transaminase (EC 2.6.1.-) PH1322 [similarit... 101 1e-20
gb|AAD24445.1|AF118389_2 (AF118389) unknown [Streptococcus suis] 101 2e-20
sp|Q01856|YRDX_RHOSH HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN R... 100 4e-20
sp|P53001|AAT1_BACSU ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A)... 99 8e-20
gb|AAK41425.1| Aspartate aminotransferase (aspB-3) [Sulfolobus s... 98 1e-19
sp|O67781|AAT_AQUAE ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 98 1e-19
emb|CAC11669.1| (AL445064) probable aspartate aminotransferase [... 98 1e-19
pir||B69764 transcription regulator GntR family homolog ycnF - B... 98 2e-19
dbj|BAB04655.1| (AP001510) aspartate aminotransferase [Bacillus ... 98 2e-19
pir||B72275 probable aspartate transaminase (EC 2.6.1.1) TM1255 ... 97 3e-19
pir||S76353 probable aspartate transaminase (EC 2.6.1.1) aspC sl... 97 4e-19
pir||A75128 probable transaminase (EC 2.6.1.-) aspB-like2 PAB181... 97 4e-19
pir||G70010 probable aspartate transaminase (EC 2.6.1.1) yugH [s... 96 5e-19
sp|O87320|AATC_RHIME PUTATIVE AMINOTRANSFERASE AATC 95 2e-18
pir||E83056 probable aminotransferase PA4715 [imported] - Pseudo... 94 3e-18
sp|P77434|YFDZ_ECOLI HYPOTHETICAL AMINOTRANSFERASE YFDZ >gi|7447... 94 4e-18
sp|Q58786|YD91_METJA PUTATIVE AMINOTRANSFERASE MT1391 >gi|212783... 93 5e-18
gb|AAG00592.1| (AF289216) alanine aminotransferase [Thermococcus... 93 5e-18
pir||D64385 aspartate transaminase (EC 2.6.1.1) - Methanococcus ... 93 6e-18
gb|AAG19034.1| (AE005003) aspartate aminotransferase; AspB1 [Hal... 92 8e-18
sp|Q58097|AAT2_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 2 (TRAN... 92 1e-17
gb|AAF65616.1|AF163769_1 (AF163769) alanine aminotransferase [Py... 92 1e-17
gb|AAF27693.1|AC018848_10 (AC018848) putative aspartate aminotra... 91 2e-17
emb|CAB77419.1| (AL160431) aspartate aminotransferase [Streptomy... 91 2e-17
pir||A83171 probable aminotransferase PA3798 [imported] - Pseudo... 91 2e-17
dbj|BAB07069.1| (AP001518) aspartate aminotransferase [Bacillus ... 91 2e-17
sp|Q60013|AAT_STRVG ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 90 4e-17
pir||B81347 aspartate transaminase (EC 2.6.1.1) Cj0762c [importe... 90 4e-17
emb|CAC03612.1| (AJ272538) putative aspartate amino transferase ... 90 5e-17
dbj|BAA96891.1| (AB018112) tyrosine aminotransferase-like protei... 89 9e-17
pir||F69863 probable transaminase (EC 2.6.1.-) ykrV [similarity]... 88 2e-16
sp|P39643|AAT2_BACSU PROBABLE ASPARTATE AMINOTRANSFERASE (TRANSA... 87 3e-16
pir||H81039 valine--pyruvate aminotransferase NMB1823 [imported]... 86 6e-16
gb|AAF12702.1|AF035157_1 (AF035157) aspartate aminotransferase [... 86 6e-16
pir||H64603 probable aspartate transaminase (EC 2.6.1.1) P0672 [... 85 1e-15
pir||D72450 probable aspartate transaminase (EC 2.6.1.1) APE2248... 84 2e-15
pir||F83189 probable aminotransferase PA3659 [imported] - Pseudo... 84 2e-15
pir||H71909 probable aspartate transaminase (EC 2.6.1.1) aspB [s... 83 4e-15
pir||D72220 probable aspartate transaminase (EC 2.6.1.1) TM1698 ... 83 4e-15
pir||T36548 probable transaminase (EC 2.6.1.-) SCH10.36 [similar... 83 7e-15
sp|P09053|AVTA_ECOLI VALINE--PYRUVATE AMINOTRANSFERASE (TRANSAMI... 82 1e-14
sp|P71348|YFBQ_HAEIN PROBABLE AMINOTRANSFERASE HI0286 >gi|157325... 82 2e-14
sp|P23034|AAT_BACSP ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 81 2e-14
pir||F81983 probable valine--pyruvate transaminase (EC 2.6.1.66)... 81 2e-14
emb|CAB45026.1| (AL078635) putative aminotransferase [Amycolatop... 81 3e-14
pir||T21518 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /... 80 5e-14
gb|AAF54707.1| (AE003693) CG6950 gene product [alt 3] [Drosophil... 77 3e-13
sp|Q59228|AAT_BACST ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 76 9e-13
pir||H69777 transcription regulator GntR family homolog ydeF - B... 75 1e-12
dbj|BAA75925.1| (AB012002) aspartate aminotransferase [Pyrococcu... 75 1e-12
pir||E82373 valine-pyruvate aminotransferase VC0019 [imported] -... 75 1e-12
dbj|BAB05414.1| (AP001512) aspartate aminotransferase [Bacillus ... 75 2e-12
sp|Q55128|AAT_SYNY3 ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 74 3e-12
gi|11498021 aspartate aminotransferase (aspB-4) [Archaeoglobus f... 74 3e-12
emb|CAB44334.1| (Y17462) cysteine conjugate beta-lyase [Fugu rub... 74 3e-12
gb|AAG19132.1| (AE005011) aspartate aminotransferase; AspB2 [Hal... 74 3e-12
pir||T35706 probable aspartate transaminase (EC 2.6.1.1) SC7H1.1... 73 6e-12
gi|6320317 Ydr111cp [Saccharomyces cerevisiae] >gi|1703231|sp|P5... 72 1e-11
pir||D75496 aspartate transaminase (EC 2.6.1.1) DR0623 [similari... 72 1e-11
gb|AAF27157.1|AC016529_20 (AC016529) putative alanine aminotrans... 72 1e-11
pir||H75379 conserved hypothetical protein - Deinococcus radiodu... 71 2e-11
emb|CAC04464.1| (AL391572) conserved hypothetical protein [Neuro... 71 2e-11
gi|4757928 cytoplasmic cysteine conjugate-beta lyase; glutamine ... 71 3e-11
sp|P77727|YFBQ_ECOLI PROBABLE AMINOTRANSFERASE YFBQ >gi|7447846|... 69 7e-11
gb|AAF07797.1|AC010704_22 (AC010704) putative aminotransferase; ... 69 7e-11
pir||B70815 probable transaminase (EC 2.6.1.-) Rv0858c [similari... 69 9e-11
>pir||E75208 probable valine--pyruvate transaminase (EC 2.6.1.66) PAB2227
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5457625|emb|CAB49116.1| (AJ248283) AMINOTRANSFERASE
[Pyrococcus abyssi]
Length = 410
Score = 825 bits (2109), Expect = 0.0
Identities = 410/410 (100%), Positives = 410/410 (100%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE
Sbjct: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
Query: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGR 120
ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGR
Sbjct: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGR 120
Query: 121 VFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVK 180
VFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVK
Sbjct: 121 VFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVK 180
Query: 181 IVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKE 240
IVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKE
Sbjct: 181 IVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKE 240
Query: 241 GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHL 300
GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHL
Sbjct: 241 GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHL 300
Query: 301 DRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVK 360
DRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVK
Sbjct: 301 DRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVK 360
Query: 361 KGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEETGV 410
KGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEETGV
Sbjct: 361 KGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEETGV 410
>pir||E71243 probable valine--pyruvate transaminase (EC 2.6.1.66) PH0207
[similarity] - Pyrococcus horikoshii
>gi|3256593|dbj|BAA29276.1| (AP000001) 428aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 428
Score = 740 bits (1890), Expect = 0.0
Identities = 352/407 (86%), Positives = 394/407 (96%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
MEE IKSMLG+VERFFSKKA+EM+ASEVRELLKLVETSDIISLAGGLPNPKTFPKEII++
Sbjct: 19 MEENIKSMLGDVERFFSKKALEMRASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIRD 78
Query: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGR 120
IL+EIME++ADKALQYGTTKGFTPLRETL+ WL KRYGIS++NDIMITSGSQQALDLIGR
Sbjct: 79 ILVEIMEKYADKALQYGTTKGFTPLRETLMKWLGKRYGISQDNDIMITSGSQQALDLIGR 138
Query: 121 VFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVK 180
VF++PGDIV+VEAPTYLAALQAFNFYEP+YIQ+PLDD GM VE LE++L++LK++GKKVK
Sbjct: 139 VFLNPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVK 198
Query: 181 IVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKE 240
+VYTVPTFQNPAGVTM+E+RRK+L+ELASEYD IV+EDDPYGELRYSG P+KKIKALD E
Sbjct: 199 VVYTVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNE 258
Query: 241 GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHL 300
GRVIYLGTFSKILAPGFRIGW+VGDPGIIRK+EIAKQSTDLCTNVFGQVVAW+YV G+L
Sbjct: 259 GRVIYLGTFSKILAPGFRIGWMVGDPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVDGGYL 318
Query: 301 DRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVK 360
++HIP+IR+FYKPRRDAMLEALEEFMPE VKWTKPEGGMF+WVTLPDGIDSKKMLE+A+K
Sbjct: 319 EKHIPEIRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLERAIK 378
Query: 361 KGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
KGVAYVPGEAFYA+RDVKNTMRLNFTYVDEDKI EG+KRLAETIKEE
Sbjct: 379 KGVAYVPGEAFYAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKEE 425
>dbj|BAA86884.1| (AB027131) multiple substrate aminotransferase (MsAT) [Thermococcus
profundus]
Length = 417
Score = 610 bits (1555), Expect = e-173
Identities = 291/408 (71%), Positives = 346/408 (84%), Gaps = 1/408 (0%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
+E+++ + N + FFS+KAM MKASEVRELLKLVETSD+ISLAGGLP P+TFP E IK+
Sbjct: 4 LEKKLSAEPINFDSFFSEKAMLMKASEVRELLKLVETSDVISLAGGLPAPETFPVETIKK 63
Query: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEN-DIMITSGSQQALDLIG 119
I +E++EEHADKALQYGTTKGFTPLR L W+EKRY I +IM +GSQQALDLIG
Sbjct: 64 IAVEVLEEHADKALQYGTTKGFTPLRLALARWMEKRYDIPMSKVEIMTVAGSQQALDLIG 123
Query: 120 RVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKV 179
RVF++PGD ++VEAPTYLAA+QAF +Y+P++I +PLDD GM V+ LE++L +L+ +GK+V
Sbjct: 124 RVFLNPGDPIVVEAPTYLAAIQAFKYYDPEFISIPLDDKGMRVDLLEEKLEELRKQGKRV 183
Query: 180 KIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDK 239
KIVYTV TFQNPAGVTMS +RRK L+ELA+EYD +++ED PY ELRYSG+P IK D
Sbjct: 184 KIVYTVSTFQNPAGVTMSVDRRKKLLELANEYDFLIVEDGPYSELRYSGEPTPPIKHFDD 243
Query: 240 EGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGH 299
GRVIYLGTFSKILAPGFRIGW+ P +IRK+EIAKQS DLCTN FGQ +AWKYV G+
Sbjct: 244 YGRVIYLGTFSKILAPGFRIGWVAAHPHLIRKMEIAKQSIDLCTNTFGQAIAWKYVENGY 303
Query: 300 LDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAV 359
LD HIPKI EFYKPRRDAMLEALEE+MPE V+WTKPEGGMFVWVTLP+GID+K M+E+AV
Sbjct: 304 LDEHIPKIIEFYKPRRDAMLEALEEYMPEGVEWTKPEGGMFVWVTLPEGIDTKLMMERAV 363
Query: 360 KKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
KGVAYVPGEAF+ +RD KNTMRLNFTYV E+ IREGV+RLAETIKEE
Sbjct: 364 AKGVAYVPGEAFFVHRDKKNTMRLNFTYVPEETIREGVRRLAETIKEE 411
>emb|CAC12318.1| (AL445066) aspartate aminotransferase related protein [Thermoplasma
acidophilum]
Length = 402
Score = 416 bits (1059), Expect = e-115
Identities = 195/400 (48%), Positives = 283/400 (70%), Gaps = 1/400 (0%)
Query: 12 VERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHAD 71
+E FS +K SE+R LLK ++IS GG+PNP++FP + +KEIL ++++ +
Sbjct: 1 MEYRFSDIFRYIKPSEIRSLLKYTSDPELISFGGGMPNPESFPIKEMKEILNDVIDNYGK 60
Query: 72 KALQYGTTKGFTPLRETLLDWLEKRYGI-SKENDIMITSGSQQALDLIGRVFIDPGDIVI 130
KALQYGTT+G PLR+ L ++EK GI +K +I++T+GSQQAL IG++F +PG+ VI
Sbjct: 61 KALQYGTTEGLDPLRDELAKYVEKTEGIRAKREEIILTTGSQQALYAIGKIFTNPGETVI 120
Query: 131 VEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQN 190
E PTY+ A+ AFN + + I + LDD GM+V+ALE+ +R A G K K +Y +PTFQN
Sbjct: 121 TEGPTYVGAISAFNSNKAEMIAIDLDDKGMDVDALEERIRNFMANGTKPKFIYVIPTFQN 180
Query: 191 PAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFS 250
PAG TM +RRK L+E++ Y++ ++ED+PYG+LRY G P IK++D +G VIYLGTFS
Sbjct: 181 PAGTTMVLDRRKQLLEISKRYEIPIVEDNPYGQLRYDGDPVPSIKSMDDDGNVIYLGTFS 240
Query: 251 KILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREF 310
K++APG R+G+++ D I+ K+ + KQ DL ++ + +A++Y+ G + R IPK
Sbjct: 241 KVMAPGLRLGYVIADRQIVEKINLVKQGLDLASDSLSEYIAYEYLKRGDIYRQIPKTVSL 300
Query: 311 YKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEA 370
Y+ +RD ML+++ E+ PE VK+TKP GGMF+WV+L + ID+ +MLE+A+K VAYV G A
Sbjct: 301 YRKKRDLMLKSIAEYFPEGVKYTKPNGGMFLWVSLDEKIDTTRMLERALKAKVAYVSGAA 360
Query: 371 FYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEETGV 410
FY + + N+MRLNFTY D+DKI EG+KRLA I EE V
Sbjct: 361 FYPHGEKHNSMRLNFTYSDDDKIVEGIKRLAYVINEEMEV 400
>pir||S75385 probable valine--pyruvate transaminase (EC 2.6.1.66) c04018
[similarity] - Sulfolobus solfataricus
>gi|1707790|emb|CAA69547.1| (Y08257) aminotransferase
[Sulfolobus solfataricus]
Length = 401
Score = 400 bits (1018), Expect = e-110
Identities = 196/397 (49%), Positives = 277/397 (69%), Gaps = 3/397 (0%)
Query: 13 ERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADK 72
ERF S + ++ SE+R+LLKL E ++ISLAGGLP+P+TFP E IK+I +I+ ADK
Sbjct: 3 ERFLSTETKYLRTSEIRDLLKLTEGKNVISLAGGLPDPQTFPVEEIKKIADDILLNSADK 62
Query: 73 ALQYGTTKGFTPLRETLLDWLEKRYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVI 130
ALQY T G + R L++ L + GIS E ++ +T GSQ+AL +I + +DPGD V+
Sbjct: 63 ALQYTATAGISEFRRELVN-LSRLRGISGIDERNVFVTVGSQEALFMIFNILLDPGDNVV 121
Query: 131 VEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQN 190
VEAPTYLAAL A +P +I + + + G +++ LE +++ + GKKVK++Y +PT QN
Sbjct: 122 VEAPTYLAALNAMRTRKPNFISITVTEMGPDLDELERKIKDAHSNGKKVKLMYVIPTAQN 181
Query: 191 PAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFS 250
PAG TM+ E RK L+E+AS+YD ++ EDD YG L + G+ IKA DKEGRVIY TFS
Sbjct: 182 PAGTTMNTEDRKRLLEIASKYDFLIFEDDAYGFLVFEGESPPPIKAFDKEGRVIYTSTFS 241
Query: 251 KILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREF 310
KILAPG R+GW++ I+++E+ KQ+ DL T Q +A + + G + ++PKIR
Sbjct: 242 KILAPGLRLGWVIAHEDFIKEMELYKQNVDLHTPSLSQYIAMEAIRRGIIQNNLPKIRRV 301
Query: 311 YKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEA 370
YK +RD MLEA+E + P + +WTKP GGMFV+ LP ID+ KMLEKA+++GVAYVPG +
Sbjct: 302 YKEKRDVMLEAIETYFPNDARWTKPVGGMFVFAWLPQKIDTTKMLEKALQRGVAYVPGSS 361
Query: 371 FYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
FYA KNTMR+NF++ ++++ EG+KRL +TIK E
Sbjct: 362 FYADYSGKNTMRINFSFPKKEELIEGIKRLGDTIKHE 398
>gb|AAK40460.1| Aspartate aminotransferase (aspB-1) [Sulfolobus solfataricus]
Length = 401
Score = 400 bits (1018), Expect = e-110
Identities = 196/397 (49%), Positives = 277/397 (69%), Gaps = 3/397 (0%)
Query: 13 ERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADK 72
ERF S + ++ SE+R+LLKL E ++ISLAGGLP+P+TFP E IK+I +I+ ADK
Sbjct: 3 ERFLSTETKYLRTSEIRDLLKLTEGKNVISLAGGLPDPQTFPVEEIKKIADDILLNSADK 62
Query: 73 ALQYGTTKGFTPLRETLLDWLEKRYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVI 130
ALQY T G + R L++ L + GIS E ++ +T GSQ+AL +I + +DPGD V+
Sbjct: 63 ALQYTATAGISEFRRELVN-LSRLRGISGIDERNVFVTVGSQEALFMIFNILLDPGDNVV 121
Query: 131 VEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQN 190
VEAPTYLAAL A +P +I + + + G +++ LE +++ + GKKVK++Y +PT QN
Sbjct: 122 VEAPTYLAALNAMRTRKPNFISITVTEMGPDLDELERKIKDAHSNGKKVKLMYVIPTAQN 181
Query: 191 PAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFS 250
PAG TM+ E RK L+E+AS+YD ++ EDD YG L + G+ IKA DKEGRVIY TFS
Sbjct: 182 PAGTTMNTEDRKRLLEIASKYDFLIFEDDAYGFLVFEGESPPPIKAFDKEGRVIYTSTFS 241
Query: 251 KILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREF 310
KILAPG R+GW++ I+++E+ KQ+ DL T Q +A + + G + ++PKIR
Sbjct: 242 KILAPGLRLGWVIAHEDFIKEMELYKQNVDLHTPSLSQYIAMEAIRRGIIQNNLPKIRRV 301
Query: 311 YKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEA 370
YK +RD MLEA+E + P + +WTKP GGMFV+ LP ID+ KMLEKA+++GVAYVPG +
Sbjct: 302 YKEKRDVMLEAIETYFPNDARWTKPVGGMFVFAWLPQKIDTTKMLEKALQRGVAYVPGSS 361
Query: 371 FYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
FYA KNTMR+NF++ ++++ EG+KRL +TIK E
Sbjct: 362 FYADYSGKNTMRINFSFPKKEELIEGIKRLGDTIKHE 398
>pir||H72293 probable valine--pyruvate transaminase (EC 2.6.1.66) TM1131
[similarity] - Thermotoga maritima (strain MSB8)
>gi|4981677|gb|AAD36207.1|AE001770_19 (AE001770)
aminotransferase, putative [Thermotoga maritima]
Length = 413
Score = 344 bits (873), Expect = 1e-93
Identities = 179/405 (44%), Positives = 254/405 (62%), Gaps = 6/405 (1%)
Query: 8 MLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIME 67
M+ N+E SK MK+S +RE+LK D IS GG+P+P+TFP++ + EI EI+E
Sbjct: 1 MVVNLEGKISKIGQNMKSSIIREILKFAADKDAISFGGGVPDPETFPRKELAEIAKEIIE 60
Query: 68 EHADKALQYGTTKGFTPLRETLLDWLEKRYGIS--KENDIMITSGSQQALDLIGRVFIDP 125
+ LQY TT+G L++ +L LE+ YGI+ E++++ T GSQQALDLIG++F+D
Sbjct: 61 KEYHYTLQYSTTEGDPVLKQQILKLLERMYGITGLDEDNLIFTVGSQQALDLIGKLFLDD 120
Query: 126 GDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGK--KVKIVY 183
+++ P YL A+ AF Y ++ VPL+D+GM++ LE +L + GK +VK +Y
Sbjct: 121 ESYCVLDDPAYLGAINAFRQYLANFVVVPLEDDGMDLNVLERKLSEFDKNGKIKQVKFIY 180
Query: 184 TVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRV 243
V F NPAGVT S E+RK L+E+A +YDL ++EDDPYG LRY G+ I + RV
Sbjct: 181 VVSNFHNPAGVTTSLEKRKALVEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGPERV 240
Query: 244 IYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRH 303
+ L TFSK+LAPG RIG + G IRK+ AKQS DLC+ +A +Y+ L
Sbjct: 241 VLLNTFSKVLAPGLRIGMVAGSKEFIRKIVQAKQSADLCSPAITHRLAARYLERYDLLEQ 300
Query: 304 IPKIREFYKPRRDAMLEALEEFMPE--NVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKK 361
+ E Y+ +R ML ALEE+ + VKW K EGG+F+W+TLP+G D+ +M E A +K
Sbjct: 301 LKPTIELYRRKRTVMLNALEEYFSDIPGVKWVKSEGGLFIWLTLPEGFDTWEMFEYAKRK 360
Query: 362 GVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
V YVPG F Y + +MRL+F ++KI EG+KRL E + E
Sbjct: 361 KVFYVPGRVFKVYDEPSPSMRLSFCLPPDEKIVEGIKRLREVVLE 405
>pir||E75378 probable valine--pyruvate transaminase (EC 2.6.1.66) DR1588
[similarity] - Deinococcus radiodurans (strain R1)
>gi|6459351|gb|AAF11148.1|AE002002_6 (AE002002)
aminotransferase, class I, putative [Deinococcus
radiodurans]
Length = 420
Score = 337 bits (855), Expect = 1e-91
Identities = 170/400 (42%), Positives = 254/400 (63%), Gaps = 14/400 (3%)
Query: 17 SKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQY 76
S++A M AS +RE+LK+ + D+IS AGGLP P+ FP + +++ + ++ ALQY
Sbjct: 28 SRRAQTMTASAIREILKITQQPDVISFAGGLPAPELFPLDAVRQAAETALSKYGPAALQY 87
Query: 77 GTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTY 136
TT+G PLRE W+ R+GI N + I +GSQQ LDL+G++ ID GD+V+VEAPTY
Sbjct: 88 STTEGHLPLRE----WIAGRHGIPAAN-VQIVTGSQQGLDLLGKILIDEGDLVLVEAPTY 142
Query: 137 LAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTM 196
L ALQ+F Y P+Y ++P D+ G++V+AL L L A+G+K K++Y +P FQNP G T+
Sbjct: 143 LGALQSFQPYLPRYAEMPTDEGGIDVDALATLLAGLAAQGEKPKLLYAIPNFQNPTGRTL 202
Query: 197 SEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKE-------GRVIYLGTF 249
S ERR+ L+EL ++Y ++VIEDDPYG+LR+SG+ + + E VIY +F
Sbjct: 203 SLERRRRLVELTAQYGVLVIEDDPYGQLRFSGEALPSLYEIGLELAGDVDRNHVIYSSSF 262
Query: 250 SKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIRE 309
SK L PG R W+ +I KL AKQ DL T Q++ + + L I ++
Sbjct: 263 SKTLVPGLRDAWVEAAAPVITKLIQAKQGADLHTPTLNQMMITELLP--LLPAQIETVKA 320
Query: 310 FYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGE 369
Y+ R ML ++EF P V +T+P+GGMF+WVTLP+G+D+ +L +AV+ VAYVPG+
Sbjct: 321 AYRERGAHMLSQMDEFFPAGVTYTRPQGGMFLWVTLPEGVDTVALLPRAVENKVAYVPGQ 380
Query: 370 AFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEETG 409
F+A NTMR++++ ++I +G++ L T +E G
Sbjct: 381 PFFALGGGANTMRMSYSSATPEQITQGMRALGATFREALG 420
>pir||F72772 probable valine--pyruvate transaminase (EC 2.6.1.66) APE0169
[similarity] - Aeropyrum pernix (strain K1)
>gi|5103559|dbj|BAA79080.1| (AP000058) 407aa long
hypothetical aminotransferase [Aeropyrum pernix]
Length = 407
Score = 330 bits (836), Expect = 2e-89
Identities = 168/404 (41%), Positives = 258/404 (63%), Gaps = 2/404 (0%)
Query: 5 IKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIE 64
++S + + +R FS+ +AS+VRELLKL E +IS AGGLP+P+ FP E + +I
Sbjct: 1 MRSDMVDYDRLFSEITRRFRASDVRELLKLTEGKRVISFAGGLPDPRVFPAEELADIARN 60
Query: 65 IMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFID 124
++ E DKALQY T G + RE L +LE+ + + +++T+GSQ+AL L +
Sbjct: 61 VVSELGDKALQYSPTPGVSIFRERALSFLERMGLKTSDRQLLVTTGSQEALFLTALSTLS 120
Query: 125 PGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYT 184
PGD+VI+E P YLAA+ F + + VP+DD G+N L + L +L AEG K K+VYT
Sbjct: 121 PGDVVIMEEPGYLAAINVFKALGARIVPVPVDDKGLNTGVLAETLDRLDAEGVKPKLVYT 180
Query: 185 VPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKK-KIKALDKEGRV 243
PT NP G TM +RR+ L++LAS YD++VIEDDPY + + ++ ++ALD EGRV
Sbjct: 181 NPTCNNPNGTTMPLDRRRELLQLASNYDMLVIEDDPYSHIAFEKTGEEVPLQALDSEGRV 240
Query: 244 IYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRH 303
+Y+ TFSKILAPG R+G + + ++E+ KQ DL T+ Q +A + + G +D+
Sbjct: 241 VYVTTFSKILAPGLRLGLTLAPSEVTARIELLKQIVDLHTSTLDQYIAAEALERGIVDKV 300
Query: 304 IPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGV 363
I + Y+ +RD M+E+LEE M WTKP GG F+++ + +D + ++ KAV++GV
Sbjct: 301 ISRAVSIYRRKRDIMIESLEENMSGVATWTKPIGGFFIFLRINGPVDMRALMPKAVERGV 360
Query: 364 AYVPGEAFYAYRDV-KNTMRLNFTYVDEDKIREGVKRLAETIKE 406
AYVPG+AF+ +NT RL++++ E++I EG+ L++ +KE
Sbjct: 361 AYVPGDAFHVTPGAGRNTARLSYSFNTEEEIPEGISILSKLVKE 404
>dbj|BAB04846.1| (AP001511) aminotransferase [Bacillus halodurans]
Length = 400
Score = 309 bits (783), Expect = 4e-83
Identities = 157/395 (39%), Positives = 247/395 (61%), Gaps = 10/395 (2%)
Query: 16 FSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQ 75
F+K+ + +S VR++LK+V +IS AGGLP+ + FP E +++ + K++Q
Sbjct: 5 FAKRVRHLHSSAVRDILKVVNQQGVISFAGGLPDDELFPLEAMEDAFSRVFAT-GKKSMQ 63
Query: 76 YGTTKGFTPLRETLLDWLEKRYGISK--ENDIMITSGSQQALDLIGRVFIDPGDIVIVEA 133
Y T+GF PLRE +L+ + ++ GI E +++IT+GSQQA+DL RV +PGD+V+ E
Sbjct: 64 YSETEGFLPLRELILERMGRK-GIRSYSERNVLITTGSQQAIDLFSRVMFNPGDVVLTED 122
Query: 134 PTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAG 193
PTYLAALQ F YE + + V DD GM E LE ++++ K K VY VPTF NPAG
Sbjct: 123 PTYLAALQVFESYEAEIVPVASDDEGMIPEDLEQKMKQ-----HKPKCVYVVPTFSNPAG 177
Query: 194 VTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKK-KIKALDKEGRVIYLGTFSKI 252
S ERRKHL+ +A ++ +++ EDDPYG+++++ + + A+D V+Y TFSK
Sbjct: 178 RVWSLERRKHLLNMAHKHHVLIFEDDPYGDIQFNQEETYVPLAAMDTGSHVLYTSTFSKT 237
Query: 253 LAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYK 312
P R GWI G ++R + AKQ+ DL +N Q ++ + +D HI ++ E Y+
Sbjct: 238 AVPALRTGWITGPFQVVRMMAQAKQANDLHSNSLSQQALYQLFTHHDMDGHIQRLIEVYR 297
Query: 313 PRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFY 372
R+D M++ L+ +++ +P+GGMF+W L + I++ ++++AV KG+AYVPGE FY
Sbjct: 298 SRKDVMIKTLQGADIPGLRFVEPKGGMFLWAELDEAINTSLLIKEAVAKGMAYVPGEPFY 357
Query: 373 AYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
A NT+RLNFT+ +KI +G+ A+ + +E
Sbjct: 358 AGVPKYNTLRLNFTHSTPEKIEKGIGIFADVVHKE 392
>pir||T36254 probable valine--pyruvate transaminase (EC 2.6.1.66) SCE68.04c
[similarity] - Streptomyces coelicolor
>gi|5123651|emb|CAB45340.1| (AL079345) putative
aminotransferase [Streptomyces coelicolor A3(2)]
Length = 404
Score = 296 bits (749), Expect = 4e-79
Identities = 155/388 (39%), Positives = 233/388 (59%), Gaps = 6/388 (1%)
Query: 19 KAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGT 78
+A + S VR++L + ++I+ AGGLP P+ F E I +++ E +ALQY T
Sbjct: 20 RARSIGGSPVRDILAVTARPEVINFAGGLPAPELFDAEGIAAAYRDVLAETPARALQYST 79
Query: 79 TKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLA 138
T+G LR L R + +DI++T+GSQQAL L+ ++PGD V+VE P YLA
Sbjct: 80 TEGEPALRAALAARTSARGLATDADDILVTTGSQQALSLLATALLEPGDTVLVERPCYLA 139
Query: 139 ALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSE 198
ALQAF F + + VP D++G++ ALE+ + + ++ K++YTVPTF NP G T+
Sbjct: 140 ALQAFGFAGARVVAVPGDEHGIDPGALEELVVR-----ERPKLLYTVPTFSNPTGRTVPA 194
Query: 199 ERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALD-KEGRVIYLGTFSKILAPGF 257
RR + E+A L ++EDDPYGELR+ G+ I + + R + LG+FSK++APG
Sbjct: 195 ARRAAVAEVAGRCGLWIVEDDPYGELRFEGERVPWIASYEGARDRTVLLGSFSKVMAPGL 254
Query: 258 RIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDA 317
R+GW+ + R +AKQ+ DL T Q+ A +Y+++ LD H+ ++ Y RRDA
Sbjct: 255 RLGWLRAPAELRRACAVAKQAADLHTPTVNQLAAARYLADRDLDAHVARVAAVYGERRDA 314
Query: 318 MLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDV 377
ML L + +P WT+PEGGMF+W LP G D+ +L + V+ VAYVPG F+A
Sbjct: 315 MLAGLADALPAGSVWTRPEGGMFLWARLPQGYDTTALLPEVVRHDVAYVPGAPFHAGEPD 374
Query: 378 KNTMRLNFTYVDEDKIREGVKRLAETIK 405
+ T+RL F D+I EG++RL E ++
Sbjct: 375 RATLRLCFVTQTPDEIAEGLRRLGEGLR 402
>pir||H83438 probable aminotransferase PA1654 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947624|gb|AAG05043.1|AE004593_5 (AE004593) probable
aminotransferase [Pseudomonas aeruginosa]
Length = 388
Score = 266 bits (672), Expect = 4e-70
Identities = 149/393 (37%), Positives = 226/393 (56%), Gaps = 16/393 (4%)
Query: 16 FSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKAL- 74
FS++ +K+S +RE+L + +++S AGGLP PK + E ++
Sbjct: 3 FSERISRLKSSLIREILAAAQRPEVMSFAGGLPAEPMLPK---------VQWEQMPASMG 53
Query: 75 QYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAP 134
QYG ++G LRE + + + ++I SGSQQ LDL ++FIDPG V++EAP
Sbjct: 54 QYGMSEGEPALREAIAAEARALGVPCEASQVLIVSGSQQTLDLASKLFIDPGTEVLLEAP 113
Query: 135 TYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGV 194
TYLAALQAF + + VPL G ++ AL L E K Y +PTFQNP+GV
Sbjct: 114 TYLAALQAFQLFGADCVTVPLGAEGPDLVALRQRL-----ERHKPAFAYLIPTFQNPSGV 168
Query: 195 TMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA 254
SEERR + L E+ + +IED+PY EL + + + ++ IY GT SK L
Sbjct: 169 RYSEERRDAVAALLDEFGVTLIEDEPYRELVFDEGRATPLVSRLRKSSWIYTGTVSKTLL 228
Query: 255 PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPR 314
PG R+G+++ P + L KQS DL TN GQ A ++ +H+ ++REFY+ R
Sbjct: 229 PGLRVGFLIATPDLFPHLLRLKQSADLHTNRVGQWQALQWFGSEAYRQHLAELREFYRVR 288
Query: 315 RDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAY 374
RDAM EAL E E +W PEGG+F W+TL +D++ +L+ A+ VA++PGE F+A
Sbjct: 289 RDAMQEALLEHFGELAEWNIPEGGLFFWLTLRQPLDTRTLLQPALAADVAFMPGEPFFAE 348
Query: 375 RDVK-NTMRLNFTYVDEDKIREGVKRLAETIKE 406
+ +RLNF++V +++ EG++RLA+ +++
Sbjct: 349 PEQNLGRLRLNFSHVAPERLHEGLRRLAKVVRD 381
>pir||T47022 hypothetical protein [imported] - Yersinia pestis
>gi|4106610|emb|CAA21365.1| (AL031866) ORF42, len=386 aa
, similarity to an aminotransferase, in P95957
Sulfolobus solfataricus, (401 aa), 33.1% identity in 393
aa overlap, Fasta scores: opt:468, E(): 8.5e-24, in
Q64602 R. norvegicus,(425 aa), 28.6% identity in 409 aa
overlap, Fa>
Length = 386
Score = 228 bits (576), Expect = 7e-59
Identities = 131/392 (33%), Positives = 217/392 (54%), Gaps = 20/392 (5%)
Query: 16 FSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQ 75
FS + ++ S +RE+L +++ +IS AGGLP ++FP + E LQ
Sbjct: 12 FSSRVNDLHPSPIREILSVIDRPGMISFAGGLPAVESFPHMSL--------EGMPQPMLQ 63
Query: 76 YGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPT 135
YG ++G LR+ + L +R E ++I SGSQQ +DL+ ++FID G V VE+PT
Sbjct: 64 YGASEGELELRQQIAQNLCERGLSCTEEQVLIISGSQQGIDLVAKLFIDEGTPVAVESPT 123
Query: 136 YLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVT 195
YLAALQ F F+ +++ ++ + ++ KL+ E K YT+PTFQNP+G
Sbjct: 124 YLAALQVFRFFGAQFVAY---------DSTQPDIDKLRTE--KPAFAYTIPTFQNPSGHC 172
Query: 196 MSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAP 255
+ E+R+ L + + L + EDDPY +L Y +K + A + IY G+FSK L+P
Sbjct: 173 LDTEQRELLAKTCDDIMLPLFEDDPYHDLVYDPCERKPVCASLQRASWIYQGSFSKSLSP 232
Query: 256 GFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRR 315
R+G++V +I L KQ+ DL ++ Q + + + H+ ++ +Y+ RR
Sbjct: 233 ALRLGYLVASSELIPYLTRLKQAADLHSSRISQWLVLQQLRSPRHTEHMHELAAYYRTRR 292
Query: 316 DAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAY- 374
DA +L+ W KP GG+F W+TL ID++++L KA+ +A++PGE+F +
Sbjct: 293 DAFEISLQRHFGSLATWKKPAGGLFFWLTLNRCIDTRQLLPKALASNIAFMPGESFLPHS 352
Query: 375 RDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
+ +RLNF++ E++ G+K LA ++E
Sbjct: 353 SEGCGQLRLNFSHATEEQADVGLKILAGLVQE 384
>pir||B69780 transcription regulator GntR family homolog ydfD - Bacillus
subtilis >gi|1881344|dbj|BAA19371.1| (AB001488) SIMILAR
TO THE RHIZOPINE CATABOLISM (MOCR) GENE OF RHIZOBIUM
MELILOTI. [Bacillus subtilis]
>gi|2632837|emb|CAB12344.1| (Z99106) similar to
transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
Length = 482
Score = 226 bits (570), Expect = 4e-58
Identities = 132/380 (34%), Positives = 213/380 (55%), Gaps = 11/380 (2%)
Query: 28 VRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRE 87
V+E+ + +D+I L+ G + + FP ++KE++ ++ + +A Y KG+ PLRE
Sbjct: 109 VQEINQSESNTDLIQLSKGELSAEIFPLAVMKEMMGKVSQHM--EAFGYEEPKGYLPLRE 166
Query: 88 TLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFY 146
L ++L K GI+ + I+I SG+ QAL LI + G V ++ P+YL +L F
Sbjct: 167 ALSNYL-KTIGINVSSSSILIVSGALQALQLISMGLLQRGSTVYLDQPSYLYSLHVFQSA 225
Query: 147 EPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIE 206
K +P+D+ G+ L + + + E + I+YT P F NP G+ MS++RR+ ++
Sbjct: 226 GMKLTGLPMDNEGL----LPENVHLTRGERGRA-ILYTNPCFHNPTGILMSKKRREEILA 280
Query: 207 LASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDP 266
++ L +IEDD Y EL P IK +DK G V+Y+G+ SK L+PG RIGWIVG
Sbjct: 281 VSENTQLPIIEDDIYRELWIDEIPPYPIKTIDKNGHVLYIGSLSKTLSPGLRIGWIVGPE 340
Query: 267 GIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFM 326
+I +L K TD ++ Q VA ++ + GH +H+ K+R+ K RR+ L ALE +
Sbjct: 341 PVIERLSDIKMQTDYGSSSLSQRVAAEWFTSGHYQQHVEKVRQQLKVRRELALSALETHL 400
Query: 327 PENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFT 386
E W P+GG FVW+ + I K + KA+ KG+ G + YA ++ N +RL++
Sbjct: 401 KEVATWNIPKGGFFVWIKILPSISMKLLYTKALSKGILINLG-SIYA-QEKGNYIRLSYA 458
Query: 387 YVDEDKIREGVKRLAETIKE 406
Y + +++G+ L IKE
Sbjct: 459 YASLEDLQKGIYELGLMIKE 478
>pir||G75446 probable valine--pyruvate transaminase (EC 2.6.1.66) DR1030
[similarity] - Deinococcus radiodurans (strain R1)
>gi|6458758|gb|AAF10603.1|AE001954_7 (AE001954)
aminotransferase, putative [Deinococcus radiodurans]
Length = 378
Score = 216 bits (544), Expect = 4e-55
Identities = 127/375 (33%), Positives = 201/375 (52%), Gaps = 13/375 (3%)
Query: 37 TSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKR 96
T +I+LA G P+ P +++ + + LQYG G LR L +L +
Sbjct: 10 TEGVINLAVGHPSLHMLPLREMEQAAAHRFAQGNAEFLQYGYEWGDGFLRTELAAYLTRE 69
Query: 97 YGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPL 155
YG I+ G+ QA+DL + PGD VIVE PTY A F + + P+
Sbjct: 70 YGFPVSAEQTFISGGTSQAIDLCCAMLTRPGDTVIVEDPTYFFAFGMFRDHGLNIVTAPV 129
Query: 156 DDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIV 215
D+ G++V+ALE + + + K+VYT+P QNPAGVT+ +ERR+ L+ LA E+ +
Sbjct: 130 DEQGLDVDALETLVAQ-----HRPKLVYTIPVHQNPAGVTLPQERREKLVRLAQEHGFTI 184
Query: 216 IEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIA 275
+ D+ Y L + G P A G+V+ LG+FSKILAPG R+GWI ++ +L
Sbjct: 185 LADEVYQLLTFEGTPPPSFAAWADTGQVVSLGSFSKILAPGTRLGWINAREDVLERL--- 241
Query: 276 KQSTDLCT----NVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVK 331
Q+ L + + G + + G L +I K+RE ++ R A+ +AL+E P +
Sbjct: 242 AQNGALVSGGGYSPLGGGMVRSMLELGLLPEYIGKLRETFRRRSRALADALDELRPLGLD 301
Query: 332 WTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDED 391
+ +P GG F+WVTLP G+ + ++L +A+ GV + PG F + RL F + +E
Sbjct: 302 FQRPTGGYFIWVTLPAGVSATELLPRALDHGVRFQPGPLFSPNGTQTDKARLCFAFYEEA 361
Query: 392 KIREGVKRLAETIKE 406
++ EGV+RL E +++
Sbjct: 362 ELVEGVRRLGEVLRQ 376
>gb|AAK43337.1| Aspartate aminotransferase (aspB-4) [Sulfolobus solfataricus]
Length = 380
Score = 208 bits (524), Expect = 9e-53
Identities = 125/367 (34%), Positives = 207/367 (56%), Gaps = 16/367 (4%)
Query: 41 ISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS 100
I++A G P+P+ P + IK+ E++ E K L Y G L + D ++
Sbjct: 26 INMASGTPDPRKMPIKEIKDAYSEVLNELGPKVLFYPGAGGQEELIREIEDKFLSVLNLT 85
Query: 101 KEND--IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDN 158
K D I++TSG+Q A++L+G+ F++ D++ VE PT++ A I + LD +
Sbjct: 86 KRKDEKIVVTSGAQHAMELLGKYFLE-NDVIAVENPTFIETFNALKLRSSSVIPISLDPS 144
Query: 159 GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIED 218
G++V LE L+ +K ++++Y +P NPAGV MSE RRK LIELA +YD +IED
Sbjct: 145 GIDVNELETLLKVVK-----IRLLYVIPNCHNPAGVNMSECRRKRLIELAEKYDFYIIED 199
Query: 219 DPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQS 278
DPY + +G+ + IK D GRVIY+ +FSKI+APG R+G+++ I K+ + +Q
Sbjct: 200 DPYRPI--AGETPQPIKNYDNNGRVIYVSSFSKIIAPGLRVGFLIAKEDIAEKISLMEQ- 256
Query: 279 TDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGG 338
D T+ Q V + + +G + ++ E YK + ++++L + + K+ +P+ G
Sbjct: 257 LDFSTSTINQYVVARLLRKGVVTERSKELYEHYKSKMKILVDSLVDKGLD--KFNEPKCG 314
Query: 339 MFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVK 398
F + L G DS + KAV+KG+++VP + F+ R RL+ + +++I EGVK
Sbjct: 315 FF--LLLDVGKDSWNVFHKAVEKGLSFVPAKPFF-LRGGDTMARLSVSVATKEEIIEGVK 371
Query: 399 RLAETIK 405
L E I+
Sbjct: 372 ILNEVIR 378
>gi|7705897 L-kynurenine/alpha-aminoadipate aminotransferase [Homo sapiens]
>gi|6165634|gb|AAF04623.1|AF097994_1 (AF097994)
L-kynurenine/alpha-aminoadipate aminotransferase [Homo
sapiens]
Length = 425
Score = 208 bits (523), Expect = 1e-52
Identities = 137/427 (32%), Positives = 228/427 (53%), Gaps = 36/427 (8%)
Query: 11 NVERFFSKKAMEMKASEVRELLKLVETS--DIISLAGGLPNPKTFP-KEIIKEI----LI 63
N RF + + S +R + ++ +ISLAGGLPNP FP K + + I
Sbjct: 2 NYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTI 61
Query: 64 EIMEEHADKALQYGTTKGFTPLRETLLDWLEK-----------RYGISK-ENDIMITSGS 111
+ EE +ALQY + G L L WL++ Y S+ + D+ +TSGS
Sbjct: 62 QFGEEMMKRALQYSPSAGIPEL----LSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGS 117
Query: 112 QQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRK 171
QQ L + + I+PGD V+++ P Y LQ+ + I V D++G+ ++L D L +
Sbjct: 118 QQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSR 177
Query: 172 LKAEGKK------VKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELR 225
K E K K +YTVP NP G +++ ER+K + ELA +YD ++IEDDPY L+
Sbjct: 178 WKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQ 237
Query: 226 YSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNV 285
++ ++D +GRVI +FSKI++ G RIG++ G +I ++ + Q + L +
Sbjct: 238 FNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPST 297
Query: 286 FGQV----VAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFV 341
F Q+ + ++ EG + H+ ++ +FY ++DA+L A ++++ +W P GMF+
Sbjct: 298 FNQLMISQLLHEWGEEGFM-AHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFL 356
Query: 342 WVTLPDGIDSKKML-EKAVKKGVAYVPGEAFYAYRDVKNT-MRLNFTYVDEDKIREGVKR 399
W+ + D K+++ EKAVK GV +PG AFY + +R +F+ +++ +
Sbjct: 357 WIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQV 416
Query: 400 LAETIKE 406
LA+ IKE
Sbjct: 417 LAQLIKE 423
>pir||E83130 conserved hypothetical protein PA4132 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950336|gb|AAG07519.1|AE004829_9 (AE004829)
conserved hypothetical protein [Pseudomonas aeruginosa]
Length = 471
Score = 206 bits (518), Expect = 5e-52
Identities = 117/394 (29%), Positives = 213/394 (53%), Gaps = 19/394 (4%)
Query: 20 AMEMKASE-VRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGT 78
A E+ SE V +L ++ D + P+P+ FP + + + + +++
Sbjct: 86 ATEVDVSELVFSVLSSIKDPDTVPFGSAFPSPQLFPLPRLARSMAHAVRDMDPQSVVADM 145
Query: 79 TKGFTPLRETLLDWLEKRYGIS----KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAP 134
T G LR + RY + +++I++G+ +AL+L +V PGD+V +EAP
Sbjct: 146 TPGNHGLRRQIA----LRYMVGGLLLPVEELVISNGALEALNLCLQVVTRPGDLVAIEAP 201
Query: 135 TYLAALQAFNFYEPKYIQVPLDDN-GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAG 193
+ A LQ + K +++P+ G+++E L D L +L +K + + FQNP G
Sbjct: 202 AFYATLQVLERLKLKAVEIPVHPREGIDLEVLADSLERLP-----IKACWFMSNFQNPMG 256
Query: 194 VTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKIL 253
+M +E+++ L EL + + + +IEDD Y EL + + K +KA D+EG V++ +FSK L
Sbjct: 257 ASMDDEKKRALAELLARHQVPMIEDDVYAELYFGQQAPKPVKAYDQEGLVMHCSSFSKSL 316
Query: 254 APGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKP 313
APG+R+GW+ G ++E K T L ++ Q Y+ G DRH+ K+R +
Sbjct: 317 APGYRVGWVAGG-RYAEQIERLKLMTSLSASIPAQAAIADYLQHGGYDRHLRKLRYALET 375
Query: 314 RRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYA 373
+++AML A+ + PE + ++P GG F+W+ LP+ +DS ++ + A+ +G++ PG F A
Sbjct: 376 QQNAMLAAVARYFPEQTRVSRPSGGYFLWLELPEAVDSLRLFQLALAQGISLAPGPIFSA 435
Query: 374 YRDVKNTMRLNFTY---VDEDKIREGVKRLAETI 404
R + RLN+ + ++K E + R+ +++
Sbjct: 436 TRRFAHCARLNYGHPWSARQEKAMETLGRITQSL 469
>gi|8393641 kynurenine aminotransferase II [Rattus norvegicus]
>gi|1050752|emb|CAA90507.1| (Z50144)
kynurenine/alpha-aminoadipate aminotransferase [Rattus
norvegicus]
Length = 425
Score = 206 bits (518), Expect = 5e-52
Identities = 136/428 (31%), Positives = 227/428 (52%), Gaps = 38/428 (8%)
Query: 11 NVERFFSKKAMEMKASEVRELLKLVETS--DIISLAGGLPNPKTFP-KEIIKEI----LI 63
N RF + ++ K S +R ++++ + DIISLA G PNPK FP K + + I
Sbjct: 2 NYSRFLTATSLARKTSPIRATVEIMSRAPKDIISLAPGSPNPKVFPFKSAVFTVENGSTI 61
Query: 64 EIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEN-------------DIMITSG 110
E +ALQY ++ G L L WL K+ I N D+ ITSG
Sbjct: 62 RFEGEMFQRALQYSSSYGIPEL----LSWL-KQLQIKLHNPPTVNYSPNEGQMDLCITSG 116
Query: 111 SQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELR 170
Q L + + I+PGD V+V P Y AL A +I VP DD G+ E L+ L
Sbjct: 117 CQDGLCKVFEMLINPGDTVLVNEPLYSGALFAMKPLGCNFISVPSDDCGIIPEGLKKVLS 176
Query: 171 KLKAEGKK------VKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGEL 224
+ K E K K +YT+P NP G +++ +R+K + ELA +YD ++IEDDPY L
Sbjct: 177 QWKPEDSKDPTKRTPKFLYTIPNGNNPTGNSLTGDRKKEIYELARKYDFLIIEDDPYYFL 236
Query: 225 RYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTN 284
+++ + ++D +GRVI + SK+++ G R+G+I G +I+++ + Q + L
Sbjct: 237 QFTKPWEPTFLSMDVDGRVIRADSLSKVISSGLRVGFITGPKSLIQRIVLHTQISSLHPC 296
Query: 285 VFGQV----VAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMF 340
Q+ + +++ EG L H+ + +FYK +RD +L A ++++ +W P+ GMF
Sbjct: 297 TLSQLMISELLYQWGEEGFL-AHVDRAIDFYKNQRDFILAAADKWLRGLAEWHVPKAGMF 355
Query: 341 VWVTLPDGIDSKKML-EKAVKKGVAYVPGEAFYAYRDVKNT-MRLNFTYVDEDKIREGVK 398
+W+ + D+KK++ EKA+++ + VPG +F+ ++ R +F+ V ++ +
Sbjct: 356 LWIKVNGISDAKKLIEEKAIEREILLVPGNSFFVDNSAPSSFFRASFSQVTPAQMDLVFQ 415
Query: 399 RLAETIKE 406
RLA+ IK+
Sbjct: 416 RLAQLIKD 423
>pir||E83392 probable transcription regulator PA2032 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9948037|gb|AAG05420.1|AE004629_9 (AE004629) probable
transcriptional regulator [Pseudomonas aeruginosa]
Length = 474
Score = 206 bits (518), Expect = 5e-52
Identities = 122/382 (31%), Positives = 205/382 (52%), Gaps = 9/382 (2%)
Query: 27 EVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHAD-KALQYGTTKGFTPL 85
+V L+ V D++ L G+P+ + + + L + HAD +AL Y G L
Sbjct: 93 QVLALVSTVPRPDVVQLGRGMPDISSPSLKPLTRSLARL-NRHADARALAYDGIHGSPLL 151
Query: 86 RETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNF 145
RE + L + +D++IT+G +AL + R +PGDIV VE+P++ A+Q+
Sbjct: 152 REEVARLLVDSGCRATASDVVITTGCHEALSVSIRAVCEPGDIVAVESPSFHGAMQSLKG 211
Query: 146 YEPKYIQVPLDD-NGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHL 204
K +++P D NG+++EALE L E +K + P NP G M E R++ L
Sbjct: 212 LGMKALEIPTDPVNGISLEALE-----LALEQWPIKAIQVTPNCNNPLGYIMPESRKRAL 266
Query: 205 IELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVG 264
+ LA YD+ +IEDD YG+L Y+ + IK+ D +GRV+ G+FSK+LAPG RIGW+V
Sbjct: 267 LALAQRYDVAIIEDDVYGDLAYTYPRPRTIKSYDDDGRVLLCGSFSKVLAPGLRIGWMVP 326
Query: 265 DPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE 324
R L + ST + + Q+ +++ GH + H+ ++R Y+ RD M++ +
Sbjct: 327 GRYADRVLHMKYISTG-ASALQPQLAIAEFIGNGHYEPHLRRMRAQYQRGRDLMIDWVAR 385
Query: 325 FMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLN 384
+ PE + ++P+GG +WV L + D+ ++ + +GV G F A +N +R+N
Sbjct: 386 YFPEGTRASRPQGGFLLWVELDEAFDTLRLDKALRNRGVQVAVGCIFSASGKYRNCLRMN 445
Query: 385 FTYVDEDKIREGVKRLAETIKE 406
+ + I + V+R+ E+ E
Sbjct: 446 YAALPTPAIEQAVRRVGESACE 467
>dbj|BAB04151.1| (AP001508) transcriptional regulator (GntR family) [Bacillus
halodurans]
Length = 482
Score = 202 bits (509), Expect = 5e-51
Identities = 120/396 (30%), Positives = 208/396 (52%), Gaps = 12/396 (3%)
Query: 13 ERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADK 72
+++ S + + V+++ + + +++ L G P + +E+L + E +
Sbjct: 94 QQYVSGGVFQPNKTYVQKINEAEFSEEVVRLGTGELAKGLLPVKQTEEVLASLSLEASH- 152
Query: 73 ALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIV 131
L Y KG LRE + +++ K YGI + ++I SG+ QAL L+ G V V
Sbjct: 153 -LSYEEAKGSLALREAVCEFVSK-YGIHVSPSSVLIVSGALQALSLMTNGLFQAGARVAV 210
Query: 132 EAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNP 191
E+P+YL +L+ + +QVPL D V+ LR+ K + + V++ YT+PTF NP
Sbjct: 211 ESPSYLMSLRILTSANIRGVQVPLAD----VQHKPSVLRQYKRQ-QDVQMFYTIPTFHNP 265
Query: 192 AGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSK 251
VT S RK L+ + L +IEDD Y EL + P +K+LD+ G V+YLG+ SK
Sbjct: 266 TNVTYSTAVRKELLHVCQAIQLPIIEDDVYRELWFDAAPPPPLKSLDQTGNVLYLGSMSK 325
Query: 252 ILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGH-LDRHIPKIREF 310
I++PG R+GW++G +I +L K TD + Q +A ++++ H +R+
Sbjct: 326 IISPGLRVGWVIGPEPVIHRLADMKMQTDYGASSISQAIAQRWLTNNDWFTSHAQFVRDK 385
Query: 311 YKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEA 370
K +R+AML+ L+E M E +W +P G ++W L +D ++ + +K V PG
Sbjct: 386 LKNQRNAMLQLLQEHMGELAEWNRPSGSFYIWCKLKHPVDMNRVFHRCLKDNVLIHPGTI 445
Query: 371 FYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
+ + + +RL+++Y +++ G+K LA I E
Sbjct: 446 YEGSK--HSYIRLSYSYETGERLEYGIKALARVIHE 479
>gi|6754408 kynurenine aminotransferase II [Mus musculus]
>gi|5106393|gb|AAD39680.1|AF072376_1 (AF072376)
kynurenine aminotransferase II [Mus musculus]
Length = 425
Score = 190 bits (479), Expect = 2e-47
Identities = 129/428 (30%), Positives = 217/428 (50%), Gaps = 38/428 (8%)
Query: 11 NVERFFSKKAMEMKASEVRELLKLVETSD--IISLAGGLPNPKTFPKE-----IIKEILI 63
N RF + ++ K S +R ++ + +ISLA G PNP FP + + I
Sbjct: 2 NYSRFLTATSLARKPSPIRTTADILSKAPKTLISLAPGSPNPSMFPFKSAAFTVENGSTI 61
Query: 64 EIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEN-------------DIMITSG 110
++ +ALQY + G L L WL K++ + N D+ ITSG
Sbjct: 62 RFEDDLIKRALQYSPSYGIPEL----LSWL-KQFQVKLHNPPTVNYPPNQGQMDLCITSG 116
Query: 111 SQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELR 170
Q L + I+PGD ++V P + L A I VP D++G+ E L+ L
Sbjct: 117 CQDGLCKAFEMLINPGDTILVNEPLFPGTLYAMKPLGCNIINVPSDEHGIIPEGLKKILS 176
Query: 171 KLKAEGKK------VKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGEL 224
+ K E K K +YTVP NP G +++ +R+K + ELA +YD ++IEDDPY L
Sbjct: 177 QWKPEDSKDPTKKTPKFLYTVPNGNNPTGNSLTGDRKKEIYELARKYDFLIIEDDPYYFL 236
Query: 225 RYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTN 284
++S + ++D +GRVI TFSK ++ G R+G++ G +I+ + + Q + +
Sbjct: 237 QFSKPWEPTFLSMDVDGRVIRADTFSKTVSSGLRVGFMTGPKTLIQNIVLHTQVSSVHAC 296
Query: 285 VFGQVVAWKYV----SEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMF 340
Q++ + + EG L HI + +FYK +RD++L A ++++ +W P+ GMF
Sbjct: 297 TLSQLMILQLLHQWGEEGFL-AHIDRTIDFYKNQRDSILAAADKWLRGLAEWHVPKAGMF 355
Query: 341 VWVTLPDGIDSKKML-EKAVKKGVAYVPGEAFYAYRDVKNT-MRLNFTYVDEDKIREGVK 398
+W+ + D+K+++ EKA+++ V VPG F+ + R +F+ ++ +
Sbjct: 356 LWIKVKGISDTKQLIEEKAIEREVLLVPGNGFFIDGSAPTSFFRASFSLATPAQMDTAFQ 415
Query: 399 RLAETIKE 406
RLA+ IKE
Sbjct: 416 RLAQLIKE 423
>pir||H83282 probable transcriptional regulator PA2897 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9948989|gb|AAG06285.1|AE004716_3 (AE004716) probable
transcriptional regulator [Pseudomonas aeruginosa]
Length = 479
Score = 190 bits (477), Expect = 3e-47
Identities = 109/363 (30%), Positives = 193/363 (53%), Gaps = 11/363 (3%)
Query: 24 KASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFT 83
++S + ++L + L +P+ P + + L ++ + +A Y + GF
Sbjct: 93 RSSIINQVLAESRREGVFPLGAAVPHVDYLPVRALHQQLAKVTRFQSPRAFSYMFSPGFE 152
Query: 84 PLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAF 143
PLR + + + + + IT G A+ + RV PGD++ E+P+Y LQ
Sbjct: 153 PLRRQVAIRMRDAGVVVDPSQVTITHGCVDAIHMALRVLTRPGDLIATESPSYYGLLQLA 212
Query: 144 NFYEPKYIQVPLDDN-GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRK 202
+ K I++P D G+++EAL+ L A +K + NP G T+ E+R+K
Sbjct: 213 DVLGLKVIEIPSDPRTGISLEALQ-----LAANQWSIKALVLTARLSNPFGGTIPEDRQK 267
Query: 203 HLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWI 262
L++L +E+++ V+EDD YGEL + + +K+ D++GRVIY +FSK ++PG RIGWI
Sbjct: 268 QLLKLTAEHNIGVVEDDIYGELMFDQGQARSLKSHDRDGRVIYCSSFSKTISPGVRIGWI 327
Query: 263 VGD--PGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLE 320
+ + IR+L+ + CT V A Y+ G DRH+ IR+ Y+ A
Sbjct: 328 IAERYQEEIRRLQ-TFTTHSACTVTQMGVAA--YLENGGYDRHLRYIRQEYRKNMTAYQL 384
Query: 321 ALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNT 380
A++++ PE + T+P+GG +WV+LP +++K++ +A+++G++ PG F N
Sbjct: 385 AVQQYFPEGTQMTRPKGGFILWVSLPAKVNTKELHVRALEQGISIAPGLIFSNTEQFNNC 444
Query: 381 MRL 383
+RL
Sbjct: 445 LRL 447
>pir||T44350 hypothetical protein [imported] - Clostridium histolyticum
>gi|3868868|dbj|BAA34256.1| (AB014075) Orf5u
[Clostridium histolyticum]
Length = 466
Score = 187 bits (469), Expect = 3e-46
Identities = 117/369 (31%), Positives = 192/369 (51%), Gaps = 14/369 (3%)
Query: 41 ISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLD--WLEKRYG 98
I L G FP + K +L E+++ KA Y G+ LR+++ + W KR
Sbjct: 106 IDLVGEATISSYFPIKNFKTVLNEVLDRDGSKAFIYKEVLGYEGLRKSINNFFWDGKR-- 163
Query: 99 ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDN 158
K +I+I SG+QQ +D+I + I+ D +IVE PTY AL F + I+VP++++
Sbjct: 164 --KSEEILIVSGAQQGIDVISKAIINVRDNIIVEKPTYNGALSVFKWRRANIIEVPIEND 221
Query: 159 GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIED 218
G++++ E L+K K+K Y + FQNP GV+ S +++K ++ELAS YD +IED
Sbjct: 222 GIDLDQFEKILQK-----NKIKCFYAMSYFQNPTGVSYSMKKKKRILELASIYDFYIIED 276
Query: 219 DPYGELRYSGK-PKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQ 277
D EL Y K+LD RVIY+ +FSKI PG R+G+++ + K
Sbjct: 277 DYLSELIYDESITYNSFKSLDINDRVIYIKSFSKIFLPGIRLGYLICPKKFLDSTINCKI 336
Query: 278 STDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEG 337
+TD+ T+ Q Y++ G+ HI +R YK + + E L + + E V + P+G
Sbjct: 337 NTDITTSSLMQRALDLYINRGYWKEHIDMLRNNYKETYNVLTEVLAKELSEEVSFNLPKG 396
Query: 338 GMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYA-YRDVKNTMRLNFTYVDEDKIREG 396
G+ +++ L +S K ++ + PG FY Y++ + ++L F+ + D+I
Sbjct: 397 GLNLYLKL-HNTNSIDFFYKCKEQNIITTPGVFFYKNYKEGLDYVKLGFSNLRTDQILSV 455
Query: 397 VKRLAETIK 405
L E K
Sbjct: 456 TNILKEIFK 464
>pir||G82405 transcription regulator GntR family VCA0871 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9658304|gb|AAF96769.1| (AE004415) transcriptional
regulator, GntR family [Vibrio cholerae]
Length = 473
Score = 184 bits (463), Expect = 1e-45
Identities = 108/376 (28%), Positives = 188/376 (49%), Gaps = 7/376 (1%)
Query: 30 ELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETL 89
++L+ + +II + P+P FP + + L + + G LR +
Sbjct: 97 DVLQRAKDPEIIPFSSAFPDPALFPHQALSRSLANASRQMLGSCMLTNLPPGSQTLRRQI 156
Query: 90 LDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPK 149
+K +DI+ITSG+ +AL+L + PGD+V +E P + LQA
Sbjct: 157 AQRYQKSGLNVLPDDIVITSGAMEALNLCLQSCTKPGDLVAIEYPAFYGVLQAIERLNLT 216
Query: 150 YIQVPLDD-NGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELA 208
+++P D +G++++ L + +K + + QNP G +MSE ++ L EL
Sbjct: 217 AVEIPTDPRDGIDLDVLASVFSSMD-----IKACWFMTESQNPLGYSMSETNKQRLAELV 271
Query: 209 SEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGI 268
+ Y + +IEDD Y EL KA DK G ++ G+FSK L+PGFRIGW+V
Sbjct: 272 NHYQIPMIEDDVYRELGIGNPSSLPAKAYDKVGNILLCGSFSKSLSPGFRIGWVVAGERA 331
Query: 269 IRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPE 328
+ + ST L +++ Q+ Y++ + D H+ K+R+ R+ A E L ++P
Sbjct: 332 LNIQRLQHLST-LSSSIPIQLGLSHYLTFYNFDHHLKKLRKLLNERKKAHAELLRTYLPH 390
Query: 329 NVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYV 388
N K GG F+WV LP I ++ + E+A++ +A PG F + + + +RLN +Y
Sbjct: 391 NTKIHLNNGGYFIWVELPQTIYAETLYEQALEHNIAIAPGILFSSDKRFSHHIRLNCSYA 450
Query: 389 DEDKIREGVKRLAETI 404
+++I + ++ L + I
Sbjct: 451 CDERIEQAIQTLGQLI 466
>sp|P39389|YJIR_ECOLI HYPOTHETICAL 53.0 KD PROTEIN IN IADA-MCRD INTERGENIC REGION (F470)
>gi|1361109|pir||S56565 hypothetical 53K protein
(iadA-mcrD intergenic region) - Escherichia coli
>gi|537181|gb|AAA97236.1| (U14003) ORF_f470 [Escherichia
coli] >gi|1790797|gb|AAC77296.1| (AE000504) putative
regulator [Escherichia coli K12]
Length = 470
Score = 178 bits (447), Expect = 1e-43
Identities = 110/380 (28%), Positives = 186/380 (48%), Gaps = 9/380 (2%)
Query: 27 EVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLR 86
+V ++L+ S I+ L+ P+ + + + L +++ + L Y G LR
Sbjct: 93 QVLDMLEAHSDSSIVPLSKSTPDVEAPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLR 152
Query: 87 ETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFY 146
E + + + +DI+ITSG ++ L PGDIV VE+P Y ++Q
Sbjct: 153 EQIARLMLDSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGM 212
Query: 147 EPKYIQVPLD-DNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLI 205
K I++P D + G++VEALE L E +K + VP NP G M + R++ ++
Sbjct: 213 GVKVIEIPTDPETGISVEALE-----LALEQWPIKGIILVPNCNNPLGFIMPDARKRAVL 267
Query: 206 ELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGD 265
LA +D+++ EDD YGEL + I + D +GRV+ +FSK +APG R+GW+
Sbjct: 268 SLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLRVGWVA-- 325
Query: 266 PGIIR-KLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE 324
PG KL K + Q+ A +V EGH RHI ++R+ Y+ + E
Sbjct: 326 PGRYHDKLMHMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIRE 385
Query: 325 FMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLN 384
+ P + T+P+GG +W+ LP+ +D + + + + G F A +N +R+N
Sbjct: 386 YFPCEICITRPKGGFLLWIELPEQVDMVCVARQLCRMKIQVAAGSIFSASGKYRNCLRIN 445
Query: 385 FTYVDEDKIREGVKRLAETI 404
+ RE +K++ E +
Sbjct: 446 CALPLSETYREALKQIGEAV 465
>pir||T46999 hypothetical protein [imported] - Yersinia pestis
>gi|4106587|emb|CAA21342.1| (AL031866) ORF19, len: 473
aa, similar to tyrosine aminotransferase, highly similar
to E. coli D90784_2, Fasta scores opt:1842, E(): 0
[Yersinia pestis]
Length = 473
Score = 176 bits (442), Expect = 4e-43
Identities = 104/360 (28%), Positives = 186/360 (50%), Gaps = 11/360 (3%)
Query: 54 PKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEN----DIMITS 109
P +++ L + A K + P E+L + +RY N +I+IT+
Sbjct: 116 PSLLLQPRLSRALASVARKISPQSSVTNLPPGNESLRRNIAQRYAACGMNVSPEEIVITA 175
Query: 110 GSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLD-DNGMNVEALEDE 168
G+ ++L L + PGD V++E+P + ALQA K I + D G+++EALE
Sbjct: 176 GAMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEALEQV 235
Query: 169 LRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSG 228
+ + +K + +P FQNP G TM +++ L+ L + + +IEDD YGEL +
Sbjct: 236 ISQYP-----IKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGA 290
Query: 229 KPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQ 288
+ KALD+ ++++ +FSK LAPGFR+GW+ R + ST + +V Q
Sbjct: 291 ERLLPAKALDQHRQILHCSSFSKCLAPGFRVGWVAAGEHAQRIQHLQLMST-VSASVPTQ 349
Query: 289 VVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDG 348
+ Y+S+G D H+ ++R + R + +A+ E P+N+K + P GG F+W+ L
Sbjct: 350 LAIADYLSQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNIKISHPAGGYFLWLELEPP 409
Query: 349 IDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEET 408
++ ++ +A+++GV+ PG F + RLN ++ ++ + ++ LA+ I + T
Sbjct: 410 FNASELYRRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQLT 469
>pir||F83124 probable transcription regulator PA4165 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950373|gb|AAG07552.1|AE004833_3 (AE004833) probable
transcriptional regulator [Pseudomonas aeruginosa]
Length = 496
Score = 173 bits (434), Expect = 3e-42
Identities = 104/363 (28%), Positives = 181/363 (49%), Gaps = 8/363 (2%)
Query: 44 AGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEN 103
A G+P +TFP + + ++++E+ +AL +G +G PLR+ + D++ G
Sbjct: 135 APGVPETRTFPLATWERLQRQVLKEYGARALTHGDPQGAEPLRQAIADYVNLERGARATA 194
Query: 104 D-IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNV 162
D +++ + SQQAL L V +D G+ + VE P Y A +AF + + VP+D+ G+
Sbjct: 195 DRVLVLTSSQQALGLCASVLLDAGERIFVEDPAYYGARKAFEAAGLECLPVPVDEQGLRP 254
Query: 163 EALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYG 222
E + A+ + + + P+ P GVT+S ERR LIE A +IEDD
Sbjct: 255 EPI-------LAQPQAARALCLTPSHHYPTGVTLSLERRLALIEWAQRQQAWIIEDDYDS 307
Query: 223 ELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLC 282
E Y+G+P ++ LD R +Y+GTF+K L PG RIG++V P ++ + +A+ D
Sbjct: 308 EFHYAGRPTACVQGLDAHERTLYIGTFTKSLFPGLRIGYMVLPPALVAPMTVARSLQDGH 367
Query: 283 TNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVW 342
Q+ ++++ GH ++ +R Y R + E + + + V+ P GG+ +
Sbjct: 368 NASLAQLTLARFIAGGHFGAYVRGMRNLYGERLGFLAERVGKRLGGLVEPRVPAGGLQMP 427
Query: 343 VTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
L GID + + A + GV V A + + + F D++ V LA+
Sbjct: 428 GLLCAGIDETRAIAAAYRAGVELVGLSALHLAAPPRAGFLMGFAAYTTDELEAAVGVLAK 487
Query: 403 TIK 405
T++
Sbjct: 488 TLR 490
>pir||B64896 hypothetical protein b1439 - Escherichia coli
>gi|1742348|dbj|BAA15069.1| (D90783) Tyrosine
aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate
aminotransferase) (TAT). [Escherichia coli]
>gi|1742355|dbj|BAA15075.1| (D90784) Tyrosine
aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate
aminotransferase) (TAT). [Escherichia coli]
>gi|1787710|gb|AAC74521.1| (AE000241) multi modular;
putative transcriptional regulator; also putative
ATP-binding component of a transport system [Escherichia
coli K12]
Length = 468
Score = 168 bits (421), Expect = 1e-40
Identities = 104/382 (27%), Positives = 193/382 (50%), Gaps = 15/382 (3%)
Query: 30 ELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETL 89
++L+ ++ A P+P+ FP + + L ++ + ++ G LR+ +
Sbjct: 95 DMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAI 154
Query: 90 LDWLEKRYGIS----KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNF 145
+RY + ++I+IT+G+ +AL+L + +PGD VIVE P + ALQA
Sbjct: 155 A----RRYALQGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALER 210
Query: 146 YEPKYIQVPLD-DNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHL 204
K + V D G++++ALE L++ VK + + QNP G T++ +++ L
Sbjct: 211 LRLKALSVATDVKEGIDLQALELALQEYP-----VKACWLMTNSQNPLGFTLTPQKKAQL 265
Query: 205 IELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVG 264
+ L ++Y++ +IEDD Y EL + + KA D+ V++ +FSK L PGFRIGW+
Sbjct: 266 VALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAA 325
Query: 265 DPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE 324
RK++ + + L T+ Q+ Y+S D H+ ++R R+ +AL
Sbjct: 326 GKH-ARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLR 384
Query: 325 FMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLN 384
++P VK + G F+W+ LP+ +D+ ++ A+ ++ PG+ F + R N
Sbjct: 385 YLPAEVKIHHNDSGYFLWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFN 444
Query: 385 FTYVDEDKIREGVKRLAETIKE 406
+ ++ + VK+L + I+E
Sbjct: 445 TAWQWGEREEQAVKQLGKLIQE 466
>gi|11435943 L-kynurenine/alpha-aminoadipate aminotransferase [Homo sapiens]
Length = 299
Score = 166 bits (416), Expect = 4e-40
Identities = 97/298 (32%), Positives = 169/298 (56%), Gaps = 13/298 (4%)
Query: 121 VFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKK-- 178
+ I+PGD V+++ P Y LQ+ + I V D++G+ ++L D L + K E K
Sbjct: 1 MIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNP 60
Query: 179 ----VKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKI 234
K +YTVP NP G +++ ER+K + ELA +YD ++IEDDPY L+++
Sbjct: 61 QKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTF 120
Query: 235 KALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQV----V 290
++D +GRVI +FSKI++ G RIG++ G +I ++ + Q + L + F Q+ +
Sbjct: 121 LSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQL 180
Query: 291 AWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGID 350
++ EG + H+ ++ +FY ++DA+L A ++++ +W P GMF+W+ + D
Sbjct: 181 LHEWGEEGFM-AHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGIND 239
Query: 351 SKKML-EKAVKKGVAYVPGEAFYAYRDVKNT-MRLNFTYVDEDKIREGVKRLAETIKE 406
K+++ EKAVK GV +PG AFY + +R +F+ +++ + LA+ IKE
Sbjct: 240 VKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKE 297
>gb|AAF42764.1|AF128839_8 (AF128839) unknown [Salmonella enteritidis]
Length = 475
Score = 165 bits (414), Expect = 7e-40
Identities = 106/383 (27%), Positives = 191/383 (49%), Gaps = 16/383 (4%)
Query: 30 ELLKLVET-SDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRET 88
E+L+L + ++ A P+P+ FP + L ++ + ++ G LR
Sbjct: 95 EMLQLASRDTSVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYA 154
Query: 89 LLDWLEKRYGIS----KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFN 144
+ +RY + ++I+IT+G+ +AL+L + PGD V+VE P + ALQA
Sbjct: 155 IA----RRYALQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALE 210
Query: 145 FYEPKYIQVPLD-DNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKH 203
K + +P D G+++ ALE L++ VK + + QNP G T+S E++
Sbjct: 211 RLRLKALSIPTDVKEGIDLMALEQALQEYP-----VKACWLMTNSQNPLGFTLSAEKKAR 265
Query: 204 LIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIV 263
L+ L + +++ +IEDD Y EL + + KA D++ V++ +FSK L PGFRIGW+
Sbjct: 266 LVALLTHHNVTLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRIGWVA 325
Query: 264 GDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALE 323
G R+++ + + L T+ Q+ Y+S D H+ ++R R+ + L
Sbjct: 326 GG-SHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLL 384
Query: 324 EFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRL 383
+P VK + G F+W+ LP+ +D+ ++ KA++ ++ PG+ F R
Sbjct: 385 RHLPAEVKIHHNDSGYFLWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRF 444
Query: 384 NFTYVDEDKIREGVKRLAETIKE 406
N + ++ + VK+L I+E
Sbjct: 445 NTAWHWGEREEQAVKQLGSLIRE 467
>pir||T39678 probable valine--pyruvate transaminase (EC 2.6.1.66) SPBC1773.13
[similarity] - fission yeast (Schizosaccharomyces
pombe) >gi|3850091|emb|CAA21918.1| (AL033389) putative
aromatic aminotransferase [Schizosaccharomyces pombe]
Length = 481
Score = 165 bits (413), Expect = 1e-39
Identities = 142/478 (29%), Positives = 232/478 (47%), Gaps = 80/478 (16%)
Query: 8 MLGNVERFFSKKAMEMKASEVR--ELLKLVETS---DIISLAGGLPNPKTFPKEIIKEIL 62
M+ N E F + E KA E ++L +++S D IS + GLP+P F I+E+
Sbjct: 1 MIRNSEDFSHHLSRESKAREKGPFQMLGRIKSSTGIDAISFSSGLPHPNKFA---IRELS 57
Query: 63 IEI------MEEHA-----------------------DKALQYGTTKGFTPLRETLLDWL 93
I+ EE+ ++LQYG +G + L + + +
Sbjct: 58 IKFPQLGCFKEENGTYAKEVNVTFNIKADPSEGLLNFSQSLQYGQCQGISELVGFIKEHI 117
Query: 94 EKRYGISKEN-DIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQ 152
+ + EN DI +++G+ L+ R+ ++ GD V+ E TY AA+ A +++
Sbjct: 118 RRIHAPRYENWDIKMSNGNTSGLEYCLRLLVNYGDHVLTEKYTYPAAITAMRALGVQFVS 177
Query: 153 VPLDDNGMNVEALEDELRKLKAE-GKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEY 211
V +D GM E+LE+ +R G + ++YTVPT QNP G T+S RRK L+ LA +Y
Sbjct: 178 VDMDSEGMLPESLEEIMRDWDISLGPRPHVLYTVPTGQNPTGSTLSLSRRKKLLALARKY 237
Query: 212 DLIVIEDDPYGELR---YSG--KPKKK--------------IKALDKEGRVIYLGTFSKI 252
D+I++ED+PY L+ Y+G P ++ + +LD EGRV+ L +FSK+
Sbjct: 238 DIIIVEDEPYYFLQMEDYNGSLNPAQQKCDGSTFLKSLVPSLLSLDTEGRVLRLDSFSKL 297
Query: 253 LAPGFRIGWIVGD----PGIIRKLEIAKQS-TDLCTNVFGQVVAWKYVSEGHLDRHIPKI 307
+APG R+G+I G+ I R E+ +S + +C +V + + EG + ++
Sbjct: 298 IAPGTRLGYITGNSMFIDHITRIAEVCTESPSGICQSVL-YAMLHNWGQEGFC-AWLQEL 355
Query: 308 REFYKPRRDAMLEALEEFMPENV-KWTKPEGGMFVWVTLPDG----IDSKKMLEK----- 357
+ Y RR+A L +++P +V + P G+F+WV L D+KK + +
Sbjct: 356 QYSYTVRRNAFLNVANKYLPNSVCIYHVPRAGLFLWVELNLNHYRFSDTKKSVSQIEMEI 415
Query: 358 ---AVKKGVAYVPGEAFYA--YRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEETGV 410
V+KGV V G+ F A R K R ++ D + EG+KR I E V
Sbjct: 416 FLALVEKGVKTVCGQFFMANPERSTKIFFRFAYSIADFEDFEEGIKRFTSVINEHFNV 473
>pir||T41409 probable valine--pyruvate transaminase (EC 2.6.1.66) SPCC569.07
[similarity] - fission yeast (Schizosaccharomyces pombe)
>gi|4757103|emb|CAB42068.1| (AL049755) putative
aminotransferase [Schizosaccharomyces pombe]
Length = 470
Score = 163 bits (409), Expect = 3e-39
Identities = 125/439 (28%), Positives = 216/439 (48%), Gaps = 66/439 (15%)
Query: 33 KLVETSDI--ISLAGGLPNPKTFP---------------KEIIKEILIEI-MEEHADK-- 72
++ SDI +S AGG PNP FP K+ K+ + + +A++
Sbjct: 29 RIQSDSDIKMLSFAGGEPNPSKFPIHKLSVSFPEVNSWEKDTNKDATVSYELSNNANEGS 88
Query: 73 -----ALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPG 126
ALQYG +G L + + D + + + K+ DI IT+G+ L+ R+ ++ G
Sbjct: 89 LDLLGALQYGQCQGIPELVKFIKDHVGQIHMPQYKDWDIKITNGNTIGLEYCLRLLVNRG 148
Query: 127 DIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAE-GKKVKIVYTV 185
D +++E TY AA+ A K+I + +D+NGM E+ E + + G + ++YT+
Sbjct: 149 DCILIEKYTYPAAITAMRPLGVKFIPIDMDENGMLPESFEKVMETWDSSLGARPHVLYTI 208
Query: 186 PTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRY-----SGKPKKK------- 233
PT QNP G T++ ERRK + LA +YD+I++ED+PY L+ + KP K+
Sbjct: 209 PTGQNPTGSTLTLERRKKFLTLAKKYDIIIVEDEPYYFLQMEKYDANWKPDKQAFNISSF 268
Query: 234 -------IKALDKEGRVIYLGTFSKILAPGFRIGWIVGD----PGIIRKLEIAKQSTDLC 282
+ LD +GRV+ + +FSK++ PG R+GWI G+ I R E+ +S
Sbjct: 269 KKKLIPSLLHLDTDGRVLRVDSFSKLIVPGLRLGWITGNSLFIDRITRYAEVCTESPSGV 328
Query: 283 TNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENV-KWTKPEGGMFV 341
+ V + ++ G L+ + ++ Y RR+A+L A ++ +P++V K+ P+ G+F+
Sbjct: 329 SQVVLYAILNRWGQNGFLE-WLQDLQNSYTMRRNALLLAADKHLPKSVCKYHSPKAGLFL 387
Query: 342 WVTLP------DGIDSK------KMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTY-- 387
WV L +D ++ + V GV V G+ F + + + F Y
Sbjct: 388 WVELDKNRLICSNMDKSISEIEMEIFVELVNNGVKPVCGQLFMGEPNSADKIFFRFAYSL 447
Query: 388 VDEDKIREGVKRLAETIKE 406
D G++R TI++
Sbjct: 448 ADLSTFEAGLERFTSTIQK 466
>gi|6321236 aromatic amino acid aminotransferase; Aro8p [Saccharomyces
cerevisiae] >gi|1723954|sp|P53090|ARO8_YEAST AROMATIC
AMINO ACID AMINOTRANSFERASE I >gi|2131620|pir||S64220
hypothetical protein YGL202w - yeast (Saccharomyces
cerevisiae) >gi|1322834|emb|CAA96914.1| (Z72724) ORF
YGL202w [Saccharomyces cerevisiae]
>gi|2231064|emb|CAA73946.1| (Y13624) aromatic amino acid
aminotransferase I [Saccharomyces cerevisiae]
Length = 500
Score = 163 bits (408), Expect = 4e-39
Identities = 135/487 (27%), Positives = 230/487 (46%), Gaps = 93/487 (19%)
Query: 16 FSKKAMEMKASEVRELLKLVETSDIISLAGGLP-------------NPKT-FPKEI---I 58
FS + K S ++ + L + +II L GGLP +PK FP+ I I
Sbjct: 13 FSDETNARKPSPLKTCIHLFQDPNIIFLGGGLPLKDYFPWDNLSVDSPKPPFPQGIGAPI 72
Query: 59 KE---ILIEIMEEHADK------------ALQYGTTKGFTPLRETLLDWLEKRYGIS-KE 102
E I + +++ADK ALQYG + G L + D + + + K+
Sbjct: 73 DEQNCIKYTVNKDYADKSANPSNDIPLSRALQYGFSAGQPELLNFIRDHTKIIHDLKYKD 132
Query: 103 NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNV 162
D++ T+G+ A + RVF + GD+++VEA ++ ++L + VP+D +G+
Sbjct: 133 WDVLATAGNTNAWESTLRVFCNRGDVILVEAHSFSSSLASAEAQGVITFPVPIDADGIIP 192
Query: 163 EALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYG 222
E L + K K++YT+PT QNP G ++++ R++ + ++A +YD +++ED+PY
Sbjct: 193 EKLAKVMENWTPGAPKPKLLYTIPTGQNPTGTSIADHRKEAIYKIAQKYDFLIVEDEPYY 252
Query: 223 ELR---YSGKPKKKIKA---------------------LDKEGRVIYLGTFSKILAPGFR 258
L+ Y K++ KA LD EGRVI + +FSK+LAPG R
Sbjct: 253 FLQMNPYIKDLKEREKAQSSPKQDHDEFLKSLANTFLSLDTEGRVIRMDSFSKVLAPGTR 312
Query: 259 IGWIVGDPGIIRKL----EIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPR 314
+GWI G I++ E+ Q+ T V ++ +G+LD + +R Y +
Sbjct: 313 LGWITGSSKILKPYLSLHEMTIQAPAGFTQVLVNATLSRWGQKGYLD-WLLGLRHEYTLK 371
Query: 315 RDAMLEALEEFMPENVKW--TKPEGGMFVWVTLPDGID--------------SKKMLEKA 358
RD ++AL +++P++ + P GMF V + + + + K
Sbjct: 372 RDCAIDALYKYLPQSDAFVINPPIAGMFFTVNIDASVHPEFKTKYNSDPYQLEQSLYHKV 431
Query: 359 VKKGVAYVPGEAFYA-----------YRDVKNT----MRLNFTYVDEDKIREGVKRLAET 403
V++GV VPG F + ++V N R + V +K+ EG+KRL +T
Sbjct: 432 VERGVLVVPGSWFKSEGETEPPQPAESKEVSNPNIIFFRGTYAAVSPEKLTEGLKRLGDT 491
Query: 404 IKEETGV 410
+ EE G+
Sbjct: 492 LYEEFGI 498
>pir||T38905 probable valine--pyruvate transaminase (EC 2.6.1.66) SPAC56E4.03
[similarity] - fission yeast (Schizosaccharomyces
pombe) >gi|2414656|emb|CAB16394.1| (Z99261) putative
aminotransferase [Schizosaccharomyces pombe]
Length = 474
Score = 157 bits (394), Expect = 2e-37
Identities = 133/458 (29%), Positives = 221/458 (48%), Gaps = 75/458 (16%)
Query: 17 SKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFP-KEIIKEI-------------- 61
S+K +KA + + + ++ IISLAGGLPNP+ FP +E+ EI
Sbjct: 18 SRKQSPLKAVALSKSSRNIK---IISLAGGLPNPEYFPIREMDAEIPAINSWKKDSSNSG 74
Query: 62 ---LIEIMEEHADK-------ALQYGTTKGFTPLRETLLDWLEKRYGISKEN-DIMITSG 110
+ + +D ALQYG G L + L + + E +I++T+G
Sbjct: 75 KLDTVSVPMSSSDSDVLPLSVALQYGQGSGAALLSQFLKEHTRIIHNPPYEGWNIIMTTG 134
Query: 111 SQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELR 170
+ LD+ R+ + GD ++VE ++ +ALQ+ I + +D G E+++D L
Sbjct: 135 NTSCLDIALRMLTNRGDSILVEKYSFPSALQSMRPLGLSCIPIDMDQFGFLPESMDDILT 194
Query: 171 KLKAEG---KKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELR-- 225
A K ++YT+PT QNP G T+S ERRK + LA ++D+I++ED+PY L+
Sbjct: 195 NWDATSYGSPKPHVLYTIPTGQNPTGSTLSVERRKQIYTLAQKHDIIILEDEPYYYLQMD 254
Query: 226 -YSGKPKKKIKA----------------LDKEGRVIYLGTFSKILAPGFRIGWIVGDPGI 268
Y GKP+ KA +D +GRVI + + SK++APG R+GW P
Sbjct: 255 AYEGKPEAADKAFTNEQFVKELIPSFLSMDVDGRVIRMDSLSKVVAPGSRVGWFTAQPLF 314
Query: 269 I----RKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE 324
I R E A QS + + + +G+L+ + IR Y RR+ +L A++
Sbjct: 315 IERGLRAAETATQSASGISQGILYAMFKHWGQDGYLE-WLKHIRYSYTLRRNYLLYAMDT 373
Query: 325 FMPENV-KWTKPEGGMFVWV--------------TLPDGIDSKKMLEKAVKKGVAYVPGE 369
++P++V + P GMF+W ++P+ I+SK E AV++GV G
Sbjct: 374 YLPKSVCSYIPPVAGMFIWFEVDKSRYIHADKNESIPE-IESKIHAE-AVEEGVNLACGN 431
Query: 370 AFYAYRDVKNTM--RLNFTYVDEDKIREGVKRLAETIK 405
F V + + R+ F + + ++ ++R A +K
Sbjct: 432 WFVVDPRVNDKIFFRVTFAHAELEEFNVAIERFAGVLK 469
>dbj|BAB05659.1| (AP001513) transcriptional regulator (GntR family) [Bacillus
halodurans]
Length = 400
Score = 157 bits (393), Expect = 2e-37
Identities = 93/298 (31%), Positives = 153/298 (51%), Gaps = 10/298 (3%)
Query: 33 KLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDW 92
+++ II G+P FP+ I ++ I E A Y +G LRE L +
Sbjct: 99 EVMSEPSIIQFRSGIPALDLFPRRIWGKLTQSICYEVEASAFNYDVPQGRPELREALSKY 158
Query: 93 LEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYI 151
++ GI I+IT+G+ QA L ++ + PGD +++E P F + K I
Sbjct: 159 VKNARGIECHPEQIVITTGATQAFTLASKLLVSPGDELVIEDPITSDIQVIFTNHGAKLI 218
Query: 152 QVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEY 211
VP+DD+G+ L + K V+ P+ Q P G +S +RR LI+ A +
Sbjct: 219 PVPVDDSGIQTCLLPQDT--------KPAFVFVTPSHQFPLGGVLSIQRRVELIQYARKR 270
Query: 212 DLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRK 271
+ ++EDD E RY G P ++ L + RV+Y+G+FSK+L+P R+G+++ P I +
Sbjct: 271 NSYIVEDDYDSEFRYEGAPIPSLQGLAPD-RVLYVGSFSKLLSPSLRLGYLILPPEFIDR 329
Query: 272 LEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPEN 329
K DL T Q+V +++ EGHL+RH+ K+R+ YK +RD +++ L + N
Sbjct: 330 GRKEKWFLDLHTPSLNQLVLARFIQEGHLERHLMKMRKSYKKKRDRLIDCLHDAFTGN 387
>gb|AAF50113.1| (AE003546) CG6321 gene product [Drosophila melanogaster]
Length = 418
Score = 156 bits (390), Expect = 5e-37
Identities = 112/412 (27%), Positives = 197/412 (47%), Gaps = 28/412 (6%)
Query: 23 MKASEVRELLKLVETSD-------IISLAGGLPNPKTFP------KEIIKEILIEIMEEH 69
+K+S+ R+L L + D I++L G P P + L E+
Sbjct: 2 LKSSQDRKLKHLFDGGDWNVYAPNILNLGVGAPGPDILTANCDSFRTATDHCLEREKREN 61
Query: 70 ADKALQYGTTKGFTPLRETLLDWLEKRYGISKE-NDIMITSGSQQALDLIGRVFIDPGDI 128
QYG T G +R + + + + D++IT+G+ L ++ +D
Sbjct: 62 QSLIFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLSTMLDFEGF 121
Query: 129 VIVEAPTYLAALQAF-NFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVK---IVYT 184
V V+ TY+ AL + +F + V L+D+G++++ LE+++ K + + KK + I YT
Sbjct: 122 VFVDEYTYMIALDSIKHFSTVTIVPVKLNDDGVDLKDLEEKVSKRRFQSKKKEFWGIYYT 181
Query: 185 VPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKP-KKKIKALDKE--- 240
+PT+ NP G+ S E + +++LA YD +V+ DD Y L Y P ++ + D
Sbjct: 182 IPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRLLSYDDRNDA 241
Query: 241 ---GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTD-LCTNVFGQVVAWKYVS 296
G VI G+FSKIL PG R+GW+ P + L+ + +T C N + +
Sbjct: 242 NFAGHVISNGSFSKILGPGVRLGWLEVPPRLKPILDGSGFATSGGCFNNYTSGIVGSLFE 301
Query: 297 EGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLE 356
+ I + E YK R A + L + +P+ K P GG F+WV +PD +D ++ L+
Sbjct: 302 LKLAQKQISESYEAYKERMLATTQVLRDELPDCCKLVSPTGGYFIWVRIPDRLDCREFLK 361
Query: 357 KAVKK-GVAYVPGEAFYA-YRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
++ + ++ G F A + K RL+ + + K+ +G +RL +K+
Sbjct: 362 YCMENHKIYFIVGTRFSADGQSGKQFFRLSIAFYPKSKLVDGARRLCNALKD 413
>pir||F69778 transcription regulator GntR family homolog ydeL - Bacillus
subtilis >gi|1881332|dbj|BAA19359.1| (AB001488) SIMILAR
TO THE RHIZOPINE CATABOLISM (MOCR) GENE OF RHIZOBIUM
MELILOTI. [Bacillus subtilis]
>gi|2632824|emb|CAB12331.1| (Z99106) similar to
transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
Length = 463
Score = 156 bits (390), Expect = 5e-37
Identities = 93/349 (26%), Positives = 176/349 (49%), Gaps = 11/349 (3%)
Query: 53 FPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGS 111
FP ++ ++ ++++ + + G G LR + ++L + G+ ++I +G+
Sbjct: 119 FPFSAWRKSMVNSLDQYGHELYRPGHVLGEFELRTLIAEYLYQSRGVHCGPEQVIIGAGN 178
Query: 112 QQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRK 171
L ++ +VF +P + E P Y A + F + +P+DD G+ ++ ++++
Sbjct: 179 PILLQILCQVF-EPNISIGYEDPGYPRARKIFEANRMNIVPIPVDDEGICIQKIKEQ--- 234
Query: 172 LKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPK 231
+ +VY P+ Q G M+ RR L++ A+E +IEDD GE RY+G+P
Sbjct: 235 ------QPNLVYVTPSHQFTLGTIMTINRRIQLLKWAAENQSFIIEDDYDGEFRYTGQPV 288
Query: 232 KKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVA 291
++ LD+ RVIY+GTFSK L P RI +++ +++K + Q+
Sbjct: 289 PSLQGLDQHNRVIYMGTFSKSLLPSLRISYMILPSPLLKKGHEITSLYKQTVSCHSQLTL 348
Query: 292 WKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDS 351
+++ G +HI ++R+ Y+ +R +LEA++ + E+V+ G+ + + +
Sbjct: 349 AEFIKNGEWQKHINRMRKLYRKKRAIVLEAVQRELGEHVRIRGENSGLRILLDVYLPFGE 408
Query: 352 KKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
K+++EKA K GV P Y + T+ L F V E IREG+K+L
Sbjct: 409 KELIEKAKKHGVKIYPVSLSYQHHPPTKTVSLGFAGVSESDIREGIKKL 457
>pir||F69838 opine aminotransferase homolog yisW - Bacillus subtilis
>gi|2145389|emb|CAA70652.1| (Y09476) YisW [Bacillus
subtilis] >gi|2633424|emb|CAB12928.1| (Z99109) similar
to opine aminotransferase [Bacillus subtilis]
Length = 213
Score = 153 bits (384), Expect = 2e-36
Identities = 75/211 (35%), Positives = 123/211 (57%), Gaps = 4/211 (1%)
Query: 196 MSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAP 255
MSE+RRK +I L+ + + +IEDD YG+L + KP + +KA+D EG ++YLG FSK ++P
Sbjct: 1 MSEQRRKEIISLSKKEQMPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGAFSKTVSP 60
Query: 256 GFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRR 315
G RIGW+ G +I +L K TD ++ Q A +++S+G+ + H+ +R K RR
Sbjct: 61 GLRIGWLAGPEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERR 120
Query: 316 DAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAY- 374
DA + LE + + W P GG ++WVT + + + +K+ V PG Y Y
Sbjct: 121 DAAVHFLERYAGDIATWRIPAGGFYIWVTFHKNLPVSRFFYELLKRQVLVNPG---YIYD 177
Query: 375 RDVKNTMRLNFTYVDEDKIREGVKRLAETIK 405
+ +N++RL+++Y + G+K AET +
Sbjct: 178 GEDRNSIRLSYSYASLGDLETGIKAAAETAR 208
>pir||T36319 probable aminotransferase - Streptomyces coelicolor (fragment)
>gi|4490636|emb|CAB38598.1| (AL035654) putative
aminotransferase [Streptomyces coelicolor A3(2)]
Length = 431
Score = 152 bits (380), Expect = 7e-36
Identities = 109/363 (30%), Positives = 182/363 (50%), Gaps = 28/363 (7%)
Query: 67 EEHADKAL-QYGTTKGFTPLRETLLDWLEKRYGISKEN-DIMITSGSQQALDLIGR-VFI 123
EE AL QYG T G +R+ + LE ++ + +++T G Q+A+ L R +F
Sbjct: 68 EERVRTALYQYGETAG--QIRDIVARMLEVDEDLTVDPASVVVTVGCQEAVLLTLRALFT 125
Query: 124 DPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVY 183
P D+++V++P Y+ A + + VP +G + E LE +R+++A G++ + +Y
Sbjct: 126 GPEDVLLVDSPAYVGITGAAGLLDIPVVPVPGTPDGPSPEGLERTVREIEASGRRARCLY 185
Query: 184 TVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRV 243
VP NP GV++ E R L++ A+ DL+++ED+PYG +S + +K+LD E RV
Sbjct: 186 VVPDCSNPTGVSLRREARTALLDAAARLDLLLLEDNPYGV--FSRVRRPTLKSLDTERRV 243
Query: 244 IYLGTFSKILAPGFRIGWIVGD----------PGIIRKLEIAKQSTDLCTNV----FGQV 289
+YLG+F+K PG R+G++V D PG++ E+AK + + N V
Sbjct: 244 VYLGSFAKTAFPGARVGFVVADQLVAGADGRPPGLLAH-ELAKVKSMVTVNTPTLSQAAV 302
Query: 290 VAWKYVSEGHLDRHIPKIREFYKPR----RDAMLEALEEFMPEN--VKWTKPEGGMFVWV 343
+ G L Y+ RD + L PE+ V+W P+GG F+ +
Sbjct: 303 AGLLLQNGGGLRAANEASARHYQSTMRCLRDTLAAELPPGAPESGGVRWNDPDGGFFLTL 362
Query: 344 TLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAET 403
+P D + A K GV + P F+ +RL+ +Y+ D+ EG RLA
Sbjct: 363 DVPFEADEAALDVSAEKYGVIWTPMRHFHLDDAGDRQIRLSCSYLTTDRAAEGATRLARF 422
Query: 404 IKE 406
+K+
Sbjct: 423 VKD 425
>pir||D83611 probable transcription regulator PA0268 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946110|gb|AAG03657.1|AE004465_3 (AE004465) probable
transcriptional regulator [Pseudomonas aeruginosa]
Length = 473
Score = 152 bits (380), Expect = 7e-36
Identities = 96/353 (27%), Positives = 167/353 (47%), Gaps = 11/353 (3%)
Query: 42 SLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISK 101
S AGG + + FP + + +++ + Y T+G LR + +L +
Sbjct: 118 SFAGGTTDKRRFPFDTWRTCVLQALRLQQRSPAFYKETEGDPELRLAISRYLAINRAVQC 177
Query: 102 E-NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGM 160
+ N +M+T G+QQ LDL+ RV +DPGD+ +VE P Y A + + VP+D G+
Sbjct: 178 DWNALMVTQGAQQGLDLLARVMLDPGDLAVVEEPGYPPARASLLATGAEVRGVPVDAEGL 237
Query: 161 NVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDP 220
V+ L D K+VY P+ Q P G+ MS ERR L++ A + ++IEDD
Sbjct: 238 RVDLLPDN----------AKLVYVTPSHQFPLGMPMSLERRLQLLDWAQRHRALIIEDDY 287
Query: 221 YGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTD 280
E R+ G+ + +++LD+ G+V YLGTFSK L P R+G+++ + + A++ D
Sbjct: 288 DSEYRFDGRSLESLRSLDRNGQVAYLGTFSKTLFPELRLGYLLPPASLREAVLAARKLVD 347
Query: 281 LCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMF 340
+ Q ++ G RH +++ Y RR +LE L + ++ G+
Sbjct: 348 RHSETLQQRALALFIQRGDFARHTRRLQREYAQRRGRLLERLHGDLSPWLEALPAVAGIH 407
Query: 341 VWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKI 393
+ + +D ++ ++G+ FYA + F ++ D I
Sbjct: 408 LAARCREPLDVLRIARHLRQQGLEVGTLPPFYAETPAQAGFLFGFGCIERDDI 460
>pir||T30600 probable transaminase (EC 2.6.1.-) PCZA361.25 [similarity] -
Amycolatopsis orientalis >gi|2894183|emb|CAA11790.1|
(AJ223998) PCZA361.25 [Amycolatopsis orientalis]
Length = 438
Score = 151 bits (378), Expect = 1e-35
Identities = 114/392 (29%), Positives = 188/392 (47%), Gaps = 37/392 (9%)
Query: 41 ISLAGGLPNPKTFPKEIIKEILIEIMEE-HADKAL----------QYGTTKGFTPLRETL 89
IS+A G P + F +I E + + D+ L QYGTTKG +
Sbjct: 47 ISMAAGRPYEEFFDVRLIHEYIDAYCDHLRHDRKLAEAVVTRTLFQYGTTKGI------I 100
Query: 90 LDWLEKRYGISKEND-----IMITSGSQQALDLIGRVF-IDPGDIVIVEAPTYLAALQAF 143
D + + + D +++T G+Q+A+ LI R D D+++ APTY+ A
Sbjct: 101 ADLIARNLAEDENIDAAAESVVVTVGAQEAMFLILRTLRADERDVLLAPAPTYVGLTGAA 160
Query: 144 NFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKH 203
+ V NG++ E L +L++ +GK+V+ Y P F NP G +M R
Sbjct: 161 LLTDTPVWPVQSTANGVDPEDLVLQLKRADEQGKRVRACYVTPNFANPTGTSMDLPARHR 220
Query: 204 LIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIV 263
L+E+A ++++ED+ YG + + +K+LD+ G V+Y+G+F+K PG R+G++V
Sbjct: 221 LLEVAEANGILLLEDNAYG--LFGSERLPSLKSLDRSGNVVYIGSFAKTGMPGARVGYVV 278
Query: 264 GDPGIIRKLEIAKQSTDL-------CTNVFGQVVAWK-YVSEGHLDRHIPKIREFYKPRR 315
D + +A Q + L + + V+A K +++ L + + Y+
Sbjct: 279 ADQRVAGGGLLADQLSKLKGMLTVNTSPIAQAVIAGKLLLNDFSLTKANAREIAIYQRNL 338
Query: 316 DAMLEALEEF---MPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFY 372
L LE +PE V W P GG FV VT+P +D + + A GV + P FY
Sbjct: 339 QLTLSELERTLGGLPE-VGWNTPTGGFFVTVTVPFVVDDELLAHAARDHGVLFTPMHHFY 397
Query: 373 AYRDVKNTMRLNFTYVDEDKIREGVKRLAETI 404
+D N +RL+ + + + I+EGV RLA I
Sbjct: 398 GGKDGFNQLRLSISLLTPELIKEGVTRLAALI 429
>pir||E82968 probable transcription regulator PA5431 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951759|gb|AAG08816.1|AE004955_10 (AE004955)
probable transcriptional regulator [Pseudomonas
aeruginosa]
Length = 491
Score = 150 bits (374), Expect = 4e-35
Identities = 108/368 (29%), Positives = 170/368 (45%), Gaps = 15/368 (4%)
Query: 46 GLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEND- 104
G+P FP + + L YG G LRE + +L G+ E +
Sbjct: 123 GVPAFDLFPFDTWARLQARFWRNPPADCLGYGDPAGEARLRELIAAYLRSARGLRCEAEQ 182
Query: 105 IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEA 164
+++T G+QQA+ L +V ++ GD V VE P Y AA AF + +D G+ +
Sbjct: 183 VIVTHGAQQAIRLCAQVLLENGDPVAVENPGYRAARLAFAATGAVPHGIDIDAEGLRSDR 242
Query: 165 LEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGEL 224
L A ++ Y P+ Q P GVT+S RR L+E A D ++EDD GE
Sbjct: 243 L--------AGIAGCRLAYVTPSHQYPTGVTLSLARRLELLEWAERADGWIVEDDYDGEY 294
Query: 225 RYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTN 284
RYSG P + ALD++GRV+Y+GTF KI P R+G++V P ++ + + +
Sbjct: 295 RYSGTPLAPLAALDRQGRVLYVGTFCKIAFPALRLGYLVVPPALVERFRQRRAIEVRHSE 354
Query: 285 VFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVT 344
V Q V +++EGH RH+ ++R + RRDA+L E P E G+ + V
Sbjct: 355 VGTQRVMADFIAEGHFQRHVRRMRRAARARRDALLWGWPE-APGCQPLPAVEAGLHLCVR 413
Query: 345 LPDGIDSKKMLEKAVKKGVAYVPGEAFY-----AYRDVKNTMRLNFTYVDEDKIREGVKR 399
+ + ++ A GV ++ D + + L F V E +I E ++
Sbjct: 414 VDSLARERALIAAAAAAGVEVSALSDYWMDDSSVAPDDRAGLVLGFAAVPEARIDEALRA 473
Query: 400 LAETIKEE 407
L + + E
Sbjct: 474 LRKAWRRE 481
>dbj|BAB12271.1| (AB047854) orf 2 [Acinetobacter sp. M-1]
Length = 469
Score = 148 bits (371), Expect = 8e-35
Identities = 105/393 (26%), Positives = 196/393 (49%), Gaps = 16/393 (4%)
Query: 16 FSKKAMEMKASEVRELLKLVETSDIISLAGGLP-NPKTFPKEIIKEILIEIMEEHADKAL 74
F KA ++ +++ ++ ++ G + +P P + ++ L ++ +
Sbjct: 82 FESKARQVSNLDLQNQIQTASIQHHLTPLGAIQLSPHLIPVDGLRRSLQRALKHCQPEDF 141
Query: 75 QYGTTKGFTPLRETLLD-WLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEA 133
Y +G LR+ L D W E ++ + DI IT+G AL L+ + GD ++V
Sbjct: 142 LYCNKQGHQQLRKALSDHWREDGIYVATD-DIFITNGCMPALSLLIQQISKEGDSILVPT 200
Query: 134 PTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAG 193
PT+ LQ + K I++P D G+++E LE +++ A K+ FQNP G
Sbjct: 201 PTFNGQLQMLASLKRKIIEIPADHRGIDLERLEFFMKQGDA-----KLCLLTANFQNPLG 255
Query: 194 VTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKIL 253
+S E+++H+ +LA +Y ++EDD YGE + + I+ D+EG VI+ G+ SK L
Sbjct: 256 YCLSNEQKQHIAQLAQKYQCFILEDDIYGECSFQKERPLPIRYWDQEGYVIWCGSVSKSL 315
Query: 254 APGFRIGWI-VGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEG---HLDRHIPKIRE 309
+ +R+GW +G + ++ + + T + + + Y S G HLD+ PK+ +
Sbjct: 316 STAYRVGWFCLGQQLQYLRPQLLANNVGVNTPLQLGLADFIY-SRGYREHLDQLRPKLMQ 374
Query: 310 FYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGE 369
+ R +L+ F + ++ +GG +W+ LP+ I ++ A KG+ VPGE
Sbjct: 375 QVEQYRAYILDV---FQGIPIGLSQSQGGYALWMQLPNSITGLELYYLAQGKGINIVPGE 431
Query: 370 AFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
F R ++ +RLN + +IR+ +++LA+
Sbjct: 432 VFGEDRRYQHFLRLNAGHALTAEIRQAIQQLAD 464
>sp|P49309|MOCR_RHIME PROBABLE RHIZOPINE CATABOLISM REGULATORY PROTEIN MOCR
>gi|1073153|pir||S51574 mocR protein - Rhizobium
meliloti >gi|468764|emb|CAA55271.1| (X78503) mocR
[Sinorhizobium meliloti]
Length = 493
Score = 147 bits (368), Expect = 2e-34
Identities = 92/363 (25%), Positives = 168/363 (45%), Gaps = 10/363 (2%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
D I+ G P K FP +L + Y G L+ + ++L G
Sbjct: 115 DRIAFHPGYPEIKAFPFSTWARLLKRHARYSHEDLYGYHWVTGHPRLKAAIAEYLRASRG 174
Query: 99 IS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDD 157
+ +++ +G+Q ALD++ R+ +D GDI +E P Y+ A + K + +P++
Sbjct: 175 VECAPEQVIVVNGTQAALDILARMLVDEGDICWMEEPGYIGAQNSLLSAGAKLVPLPVER 234
Query: 158 NGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIE 217
+G + LEDE R ++++ P+ Q P G M E R L+++ +D ++E
Sbjct: 235 DGWS---LEDETRP------SPRLIFVTPSCQWPLGCLMRMEDRLRLLQIGERHDAWIVE 285
Query: 218 DDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQ 277
DD E R+ G+P ++ LDK GRVIY+GTF+K L P RIG+IV P + +
Sbjct: 286 DDYDSEYRFRGRPVPAMQGLDKSGRVIYMGTFAKTLFPSLRIGFIVVPPQLADGFKRVVS 345
Query: 278 STDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEG 337
+T ++ Q ++SEG+ H+ ++R Y R+ + + + + + +
Sbjct: 346 NTGHYPSLLLQAALADFISEGYFATHLRRMRRLYAERQKVFVALCRRHLADWLTIDENDA 405
Query: 338 GMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGV 397
GM + ++ + + A +GV + P + + + L + +D +REG+
Sbjct: 406 GMQLVARFTRALEDEVLWRAAQGQGVNFSPLSRQFFHSPPQQGAILGYAGIDPKTMREGI 465
Query: 398 KRL 400
L
Sbjct: 466 NSL 468
>gb|AAC31185.1| (AF076240) putative regulatory protein MocR [Rhizobium
leguminosarum bv. viciae]
Length = 488
Score = 146 bits (365), Expect = 4e-34
Identities = 90/358 (25%), Positives = 167/358 (46%), Gaps = 10/358 (2%)
Query: 41 ISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS 100
I+ G P K+FP +L + Y G L+ + ++L+ G+
Sbjct: 117 IAFHPGYPEIKSFPFSTWARLLKRHTRYSQEDLYGYHWVTGHPRLKTAIAEYLQASRGVD 176
Query: 101 -KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNG 159
+++ +G+Q ALD++ RV +D GD+ +E P Y+ A A + + +P+ +G
Sbjct: 177 CGPEQVIVVNGTQAALDILARVLVDEGDVCWMEEPGYIGAQNALLSAGARLVPLPVGRDG 236
Query: 160 MNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDD 219
+ L+DE R ++++ P+ Q P G M E R L+++A +D ++EDD
Sbjct: 237 WS---LDDEARPAP------RLIFVTPSCQWPLGCVMRMEDRLRLLQIAERHDAWIVEDD 287
Query: 220 PYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQST 279
E R+ G+P ++ LDK GRVIY+GTF+K L P RIG++V P + + +T
Sbjct: 288 YDSEYRFRGRPIPAMQGLDKSGRVIYMGTFAKTLFPSLRIGFVVVPPHLADGFKRVASNT 347
Query: 280 DLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGM 339
++ Q ++SEG+ H+ ++R Y R+ + + + + + GM
Sbjct: 348 GHYPSLLLQAALADFISEGYFATHLRRMRRLYAERQKVFVSMCHRSLNRWLSIEESDAGM 407
Query: 340 FVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGV 397
+ ++ + + A K+GV + P + + L + +D +REG+
Sbjct: 408 QLVGRFTQAVEDETLWAAAQKQGVNFSPLSRQFFSSPPEQGAILGYAGIDLKAMREGI 465
>dbj|BAB04297.1| (AP001509) transcriptional regulator (GntR family) [Bacillus
halodurans]
Length = 469
Score = 146 bits (365), Expect = 4e-34
Identities = 89/352 (25%), Positives = 180/352 (50%), Gaps = 13/352 (3%)
Query: 54 PKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQ 112
P ++ K + E+++ +++ L YG G LR+ L +L + G+S + ++IT+G+Q
Sbjct: 125 PLKVWKRHVQEVLKGASEELLMYGDPFGDWHLRQELSHYLLQSRGVSCRPEQVVITAGTQ 184
Query: 113 QALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKL 172
A+ L+ ++ G V E P Y F + +P++ +G+++ L +
Sbjct: 185 HAVSLLCQLLSLHGSTVAFEDPGYNGVRSVFINQGCRIAPIPIEADGLSLSRLHES---- 240
Query: 173 KAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKK 232
IVY P+ Q P G+ + +R L+E A E++ ++EDD E RY G+P
Sbjct: 241 -----HANIVYVTPSHQLPCGMILPVHKRSLLLEWAYEHEGYIVEDDYDSEFRYQGQPIP 295
Query: 233 KIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAW 292
+KALD+ +VIYLGTFSK P R+ ++V ++ + + + + Q +
Sbjct: 296 ALKALDQNEKVIYLGTFSKSFLPSIRVSYMVLPGELVPLYQQKLANYNQAASQLIQRALY 355
Query: 293 KYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSK 352
++ +G RHI ++++ Y+ + +L++++ ++ + V + G+ V + +P G +
Sbjct: 356 TFIKDGDFQRHIRRMKKVYQSKHHTLLKSVKTYLGDRVTVIGEKSGLHVLLNVP-GREDH 414
Query: 353 KMLEKAVKKGVAYVPGEAFY--AYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
+++EKA+ GV + F+ + + L F + E+ I++G++RL +
Sbjct: 415 ELIEKAMACGVKVYSTKTFWYNPKNQCSSFIMLGFGKLSEEAIKKGIRRLQQ 466
>pir||G82984 probable transcription regulator PA5283 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951597|gb|AAG08668.1|AE004941_1 (AE004941) probable
transcriptional regulator [Pseudomonas aeruginosa]
Length = 458
Score = 141 bits (351), Expect = 2e-32
Identities = 90/317 (28%), Positives = 151/317 (47%), Gaps = 10/317 (3%)
Query: 76 YGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPT 135
Y T G LR+ + L I+ T+G+ ALDL+ R + PGD+V+VE P
Sbjct: 143 YSTPLGLPALRQHIQKRLRLIDIHVDPEQILTTTGASHALDLLVRTLLKPGDVVVVENPG 202
Query: 136 YLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVT 195
Y F+ K + VP +G + ALE LR K K ++T + NP G +
Sbjct: 203 YYNLFNLLKFHGVKMLGVPRTRHGPDTAALETILR-----AHKPKFLFTNSMYHNPTGTS 257
Query: 196 MSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAP 255
+S +++LA ++D ++EDD Y + + P ++ LD RVIYL +FSK L+
Sbjct: 258 LSPSVAHRVLQLAEQHDFHIVEDDIYAD--FQNGPSTRLATLDSLRRVIYLASFSKTLSC 315
Query: 256 GFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRR 315
R+G+++ P +IR+L K T + + F + V ++ G + + ++R+ +
Sbjct: 316 SLRVGYLIAGPELIRRLADVKMYTSIGSQRFAECVVSTMLANGSYRKLVQRLRQRLTRQM 375
Query: 316 DAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYR 375
A L L + E + +P GGMFVW + D ++ A + V PG F
Sbjct: 376 AATLRVLGDNGWE--VFAEPVGGMFVWARIGD-YPFAELQAVATRLDVLLSPGSGFSPEG 432
Query: 376 DVKNTMRLNFTYVDEDK 392
+ + +R+N Y + +
Sbjct: 433 EESDWLRINIAYASDPR 449
>dbj|BAB06414.1| (AP001516) transcriptional regulator (GntR family) [Bacillus
halodurans]
Length = 462
Score = 138 bits (344), Expect = 1e-31
Identities = 93/351 (26%), Positives = 170/351 (47%), Gaps = 18/351 (5%)
Query: 53 FPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEK-RYGISKENDIMITSGS 111
FP I ++ + E + H + +G G PLR + D++ K R E ++I G
Sbjct: 121 FPLSIWRKCVNETLLNHETRFNHHGAKLGELPLRAAVADYVTKSRILDCTEEQVVIFEGI 180
Query: 112 QQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRK 171
+ +++++ +F G I+E P+Y F+ ++ +VP +++E L+++
Sbjct: 181 EHSMNILSLLFKQMGKTAIMEQPSYKVIEDIFSLHQLPIQRVPSPKGVLSLEDLQEQ--- 237
Query: 172 LKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPK 231
K ++Y P+ Q P G +S + R +I A + VIEDD GE RY P
Sbjct: 238 ------KNGVLYLTPSHQYPYGSFLSIQERIKIINWAQNSESYVIEDDYDGEFRYDIDPV 291
Query: 232 KKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVA 291
++ L K VIY+GTFSK L+P R+ + + P ++++ + +V Q+
Sbjct: 292 PSLQGLSKN-HVIYIGTFSKTLSPAIRVSYAILPPELMKRYQEVCSMFPSPVSVHLQLAL 350
Query: 292 WKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDS 351
K++ +GH +RHI ++R++YK ++D ++ ++E M ++ G+ + + L +
Sbjct: 351 AKFMEDGHYERHIRRMRKYYKEKQDFLIATIQEVMGDHAALHGTTAGLHLVLELKNNSRP 410
Query: 352 KKMLEKAVKKGVAYVPGEAFYAYRDVKNT--MRLNFTYVDEDKIREGVKRL 400
K L A A G Y +DV L F+ + +KI EG++RL
Sbjct: 411 YKQLLAA-----ARAHGVNIYPVKDVTPNPYFILGFSGLPREKITEGIRRL 456
>sp|Q08792|YCXD_BACSU HYPOTHETICAL 50.8 KD PROTEIN IN SRFA4-SFP INTERGENIC REGION (ORF8)
>gi|2127082|pir||I40492 gntR-type transcription
regulator homolog ycxD - Bacillus subtilis
>gi|396486|emb|CAA49821.1| (X70356) ORF8 [Bacillus
subtilis] >gi|1805428|dbj|BAA08990.1| (D50453) homologue
of mocR gene product of Rhizobium meliloti [Bacillus
subtilis] >gi|2632642|emb|CAB12150.1| (Z99105) similar
to transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
>gi|2632657|emb|CAB12164.1| (Z99106) similar to
transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
Length = 444
Score = 136 bits (339), Expect = 5e-31
Identities = 102/366 (27%), Positives = 169/366 (45%), Gaps = 12/366 (3%)
Query: 41 ISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS 100
I A P+P FP + + + ++ + + YGT KG L L L + +
Sbjct: 81 IDFATSAPDPDVFPYLDFQHCINKAIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFA 140
Query: 101 KENDIMITSGSQQALDLIGRV-FIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNG 159
E I ITSG QQAL L+ + F + + + +E P Y ++ I V + G
Sbjct: 141 DERHIFITSGVQQALSLLCAMPFPNGKEKIAIEQPGYHLMVEQLETLGIPAIGVKRTEEG 200
Query: 160 MNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDD 219
+++ +E R + E +K YT+P F NP G ++SE ++ L+ LA YD+ ++EDD
Sbjct: 201 LDIAKVE---RLFQTES--IKFFYTMPRFHNPLGCSLSERDKQELVRLAEAYDVYLVEDD 255
Query: 220 PYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQST 279
G+L K + A D VIYL +FSK++ PG R+G V + K+
Sbjct: 256 YLGDLE-ENKKADPLYAYDLSSHVIYLKSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLN 314
Query: 280 DLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMP-ENVKWTKPEGG 338
D+ ++ Q Y+ G RH KIR+ YK R + +A+ + ++T G
Sbjct: 315 DIDCSMISQAALEIYLKSGMYGRHKEKIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQ 374
Query: 339 ---MFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVK-NTMRLNFTYVDEDKIR 394
M + LP + + +++ + K+GV + Y K N +++N + V + I
Sbjct: 375 APCMHTHLVLPQDLPASRVIHRLEKQGVLLEAIDRHYLSDYPKENLLKINISNVKTEDIE 434
Query: 395 EGVKRL 400
GVK L
Sbjct: 435 RGVKLL 440
>pir||G72655 aspartate transaminase (EC 2.6.1.1) APE0674 [similarity] -
Aeropyrum pernix (strain K1) >gi|5104332|dbj|BAA79647.1|
(AP000060) 405aa long hypothetical aspartate
aminotransferase [Aeropyrum pernix]
Length = 405
Score = 136 bits (338), Expect = 6e-31
Identities = 123/396 (31%), Positives = 190/396 (47%), Gaps = 30/396 (7%)
Query: 24 KASEVRELLKLVETSDIISLAGGLPN--PKTFPKEIIKEILIEIMEEHADKALQYGTTKG 81
K VRE L E D+I L+ G P P TF +E + + L++ E + Y T G
Sbjct: 23 KIDAVRERLAR-EGRDVILLSTGQPGFLPPTFLRERLAQALLD---EGFKRLYSYTPTPG 78
Query: 82 FTPLRETLLDWLEKRYGISKE-NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAAL 140
+ +RE + + L G E +DI++T+G Q+A+ ++PGD VI+ PTY
Sbjct: 79 YADVREAIAEDLAALGGPRMEPDDILVTAGGQEAMFATLSTILEPGDKVILMDPTYFGYR 138
Query: 141 QAFNFY--EPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSE 198
+ ++++ P ++ DE R +A + VK V V NP G +S
Sbjct: 139 PIVEYLGGRVEWVRAP-----PSLGFQPDEERLKEAFTRDVKAVVLVSP-DNPTGRLLST 192
Query: 199 ERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA-PGF 257
E K + +LA + ++ D+ Y L + G+ K I + TFSK PG+
Sbjct: 193 ESAKLVADLAVDTGAWIVYDEAYKTLVFEGEHVYLYKLAPDN--TISINTFSKDPGFPGW 250
Query: 258 RIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVS--EGHLDRHIPKIREFYKPRR 315
R+G++ G I+ K+ + + C QV A Y+ EG L RH+ REF K R
Sbjct: 251 RLGYLYGPGWIVGKIRLVSEELVYCPPSIAQVAAKIYLEDREGRL-RHLEYAREFLKTRM 309
Query: 316 DAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-----GIDSKKMLEKAV-KKGVAYVPGE 369
+AM ALEE +PE V + +P G MF+ V L I S+ + K + ++ VA VPG
Sbjct: 310 EAMAGALEEMLPEAV-FARPGGSMFITVDLSSYLSKASITSEDLSVKLLDEESVATVPGR 368
Query: 370 AFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIK 405
F D +RL+F ++IREG+ RLA ++
Sbjct: 369 YFGPSGD--TMLRLSFATETPERIREGIGRLARLLE 402
>pir||G69825 transcription regulator GntR family homolog yhdI - Bacillus
subtilis >gi|2226204|emb|CAA74493.1| (Y14082)
hypothetical protein [Bacillus subtilis]
>gi|2633283|emb|CAB12787.1| (Z99109) similar to
transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
Length = 469
Score = 129 bits (321), Expect = 6e-29
Identities = 88/356 (24%), Positives = 167/356 (46%), Gaps = 11/356 (3%)
Query: 46 GLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKE-ND 104
G +P FP ++ +++ ++ ++ G +G LR + ++ G++ E
Sbjct: 113 GSVDPTLFPFNAWRKSIVKSLDRYSGSFHTSGDPQGEYELRHMIARFVRLSRGVNCEPGQ 172
Query: 105 IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEA 164
I+I +G+ L + + + PG + E P + + + F + D G+
Sbjct: 173 IIIGAGTTVLLQNLC-LSLKPGTKIGFEEPGFHRSRRMFEANHMDVTPICSDAEGV---- 227
Query: 165 LEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGEL 224
L DEL + + ++YT P+ Q P G M+ RR+ L+ A+E + +IEDD GE
Sbjct: 228 LPDELYR-----QNPYLMYTTPSHQFPIGTIMTITRRQELLAWAAETNSFIIEDDYDGEF 282
Query: 225 RYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTN 284
RYSG P ++ LD GRVIYLGTFSK L P R+ +++ P ++ ++ Q +
Sbjct: 283 RYSGHPIPSLQGLDPNGRVIYLGTFSKSLLPSLRLSFMIVPPELMEPIQNNVQLMKQTVS 342
Query: 285 VFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVT 344
Q+ ++ G +HI ++R Y+ + +LEA+ + V+ G+ + +
Sbjct: 343 AHSQLALADFIETGEWQKHINRMRSLYRKKHAVLLEAIRSELGNTVEILGKNSGLHILLR 402
Query: 345 LPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
L ++ ++ A GV P Y + ++ + + + E+ IR G+++L
Sbjct: 403 LLFPASEEEAIQAAADHGVTLYPVSPSYIEQTPFTSVLIGYGGLSEEDIRLGIQKL 458
>emb|CAB99169.1| (AL390188) putative gntR-family regulatory protein [Streptomyces
coelicolor A3(2)]
Length = 507
Score = 127 bits (317), Expect = 2e-28
Identities = 94/312 (30%), Positives = 144/312 (46%), Gaps = 13/312 (4%)
Query: 38 SDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRY 97
+D + G P+ FP+ ++ E ++L Y +G LR L + L +R
Sbjct: 117 ADRVDFVPGTPDLSLFPRSAWAAAQRGVLTELEHESLGYPDPRGLPRLRTALAELLARRR 176
Query: 98 GISKEND-IMITSGSQQALDLIGRVFIDPGDIVI-VEAPTYLAALQAFNFYEPKYIQVPL 155
G+ + + IM+ SG QA L+ V G VE P + + +PL
Sbjct: 177 GVVADPERIMVVSGVAQATSLLASVLHARGTRTAGVEDPGSPQHHALYGAAGLGTVPLPL 236
Query: 156 DDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIV 215
DD G+ L A G V++V P Q P G+ S RR L++ A D +V
Sbjct: 237 DDEGLATGPLY-------ASG--VRLVVATPAHQFPTGIAYSARRRAELLDWARSVDGLV 287
Query: 216 IEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIA 275
+EDD G+ RY P ++ LD E RV Y G+ SK LAPG R+GW++ + +
Sbjct: 288 LEDDYDGDFRYDRAPVGALQGLDPE-RVAYTGSVSKSLAPGLRLGWLLVPDWLADDVVER 346
Query: 276 KQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKP 335
K++TDL Q + ++V G DR + + Y+ RRD ++ AL E+ P + T
Sbjct: 347 KRTTDLGHPALDQALFARFVERGDYDRQLRVCQRAYRERRDTLVGALAEYFP-GARVTGI 405
Query: 336 EGGMFVWVTLPD 347
G+ VTLP+
Sbjct: 406 AAGLHAIVTLPE 417
>pir||D75469 probable regulatory protein MocR - Deinococcus radiodurans (strain
R1) >gi|6458556|gb|AAF10417.1|AE001938_3 (AE001938)
regulatory protein MocR, putative [Deinococcus
radiodurans]
Length = 477
Score = 126 bits (314), Expect = 4e-28
Identities = 86/331 (25%), Positives = 152/331 (44%), Gaps = 13/331 (3%)
Query: 76 YGTTKGFTPLRETLLDWLEKRYGISKEND-IMITSGSQQALDLIGRVFIDPGDIVIVEAP 134
Y G LR + ++ + G++ D +++T+G+ Q+L L+ R + G V+ E P
Sbjct: 149 YADAAGLPELRAAVSAFVGRSRGLAATPDTLLLTAGTLQSLGLLARAVLPAGATVLFENP 208
Query: 135 TYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGV 194
Y A + + +P+D++G V+ L VY P+ Q P G
Sbjct: 209 GYRAGRAVLEGAGLRLVPLPVDEDGPVVDNLPP-----------AHAVYVTPSHQFPLGS 257
Query: 195 TMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA 254
+S RR L+ A +++EDD GE RY P + +LD RV+YLGTFSK+L+
Sbjct: 258 RLSLPRRLALLAWAERQGALILEDDYDGEFRYDVPPLPPLASLDTARRVVYLGTFSKVLS 317
Query: 255 PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPR 314
P R G++V P ++ L + TD Q ++ G +DRH+ + R ++
Sbjct: 318 PALRTGFVVAAPALLAALSHERALTDGGHAPALQHALLHLLTSGEVDRHVRRARRWHAQV 377
Query: 315 RDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAY 374
R+A+ L P E G+ V + L +D++ + ++ ++GV F
Sbjct: 378 REALTAELSPLAP-LATLRGIEAGLHVCLHLAPPLDAETVAQELAERGVYVETLRTFTFT 436
Query: 375 RDVKNTMRLNFTYVDEDKIREGVKRLAETIK 405
KN + L + + + + G +R+ E ++
Sbjct: 437 EPPKNALVLGYGGLTVKEAQAGARRIREVVE 467
>gb|AAF13752.1|AF117351_9 (AF117351) putative regulatory protein [Zymomonas mobilis]
Length = 317
Score = 126 bits (314), Expect = 4e-28
Identities = 83/270 (30%), Positives = 138/270 (50%), Gaps = 7/270 (2%)
Query: 40 IISLAGGLPNPKTFPK-EIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
+++++ G P+P+ P+ E+I+ + Y +G T LR L + G
Sbjct: 45 MLNISDGTPDPRLVPRSELIRAFRHALGTPAFLSGASYVDPRGTTELRIALAETFFDARG 104
Query: 99 IS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDD 157
+S ++IMIT GSQ L L + P D++ VE P Y A AF K I +P+D+
Sbjct: 105 VSISPDEIMITHGSQMGLFLAASALLKPSDVIAVENPGYPYAWAAFRATGAKIIGIPVDE 164
Query: 158 NGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIE 217
+G++VE +L + E ++ VY P Q P VT+ RR L+E+A +++L +IE
Sbjct: 165 DGIDVE----KLAIIAEETPALQAVYVTPHHQYPTTVTLGMGRRLRLLEIARQHNLTLIE 220
Query: 218 DDPYGELRYSGKPKKKIKA-LDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAK 276
DD E R+ KP + A + I+LG FSK+LAP R+G+++ P I+ ++ +
Sbjct: 221 DDYDHEYRFDSKPILPLVARAYHQQPFIHLGPFSKLLAPTIRLGYVIAPPDIMARMMAYR 280
Query: 277 QSTDLCTNVFGQVVAWKYVSEGHLDRHIPK 306
+S D ++ ++ + G L RH K
Sbjct: 281 ESIDRQGDIPLELALASMIENGDLGRHSRK 310
>gi|11499215 aspartate aminotransferase (aspB-3) [Archaeoglobus fulgidus]
>gi|7447819|pir||F69452 probable aspartate transaminase
(EC 2.6.1.1) aspB3 AF1623 [similarity] - Archaeoglobus
fulgidus >gi|2648929|gb|AAB89620.1| (AE000990) aspartate
aminotransferase (aspB-3) [Archaeoglobus fulgidus]
Length = 390
Score = 126 bits (313), Expect = 5e-28
Identities = 107/400 (26%), Positives = 191/400 (47%), Gaps = 27/400 (6%)
Query: 12 VERFFSKKAMEMKASEVRELLKLVE-TSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHA 70
+ R +++ E+K S +R LV D+ISL G P+ P I +E++ + + +
Sbjct: 9 LSRRLARRVEELKPSGIRRFFDLVVGRDDVISLGVGEPDFPV-PWRIREEMIYSLEKGYT 67
Query: 71 DKALQYGTTKGFTPLRETLLDWLEKRYGISK-ENDIMITSGSQQALDLIGRVFIDPGDIV 129
Y + G LRE + ++ R+G+ +M+TSG + +D+ R I+PGD
Sbjct: 68 S----YTSNLGLPELREGIAEYYT-RFGVKALPEQVMVTSGVSEGVDIAIRALIEPGDAA 122
Query: 130 IVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQ 189
++ P Y++ + + +P + + R KA+ +V P
Sbjct: 123 LIPEPCYVSYKPLVEICGGEAVTIPTAPEFRLTYEMLMQYRDAKAK----ILVLNYPA-- 176
Query: 190 NPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTF 249
NP GV+ S++ + + + +E DLIV+ D+ Y EL Y+G+ E RV+ F
Sbjct: 177 NPTGVSYSKKELEEIADAVNELDLIVLSDEIYAELTYTGRHVSMAALNGMEDRVVIFNGF 236
Query: 250 SKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIR 308
SK A G R+G+++ P I + Q LC + GQ+ A + + LD + ++R
Sbjct: 237 SKAFAMTGMRVGYVIAPPDIFAGMLKIHQYCMLCAPITGQIGAIEALRS--LD-EVERMR 293
Query: 309 EFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEK-AVKKGVAYV 366
Y RR+ +++ L E + KPEG + + + G+ S++ EK ++K VA V
Sbjct: 294 AEYMRRRNFVVKRLSEIF----EIKKPEGAFYAFPKISSTGMSSEEFAEKLLLEKSVAVV 349
Query: 367 PGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
PG AF + +RL + V +K++E + R+ E ++E
Sbjct: 350 PGNAFGECGE--GYVRLAYA-VKFEKLKEAMDRIKEFVEE 386
>pir||A75353 mocR protein - Deinococcus radiodurans (strain R1)
>gi|6459563|gb|AAF11342.1|AE002020_1 (AE002020) mocR
protein [Deinococcus radiodurans]
Length = 479
Score = 124 bits (308), Expect = 2e-27
Identities = 84/298 (28%), Positives = 139/298 (46%), Gaps = 18/298 (6%)
Query: 105 IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEA 164
I++T G+Q +LD + R+ ++PG + + E P Y A AF+ + + +D G+
Sbjct: 194 ILLTGGTQSSLDALSRILLEPGRLAVTEQPGYPGAHAAFSATGAQVLGAAVDGGGLRPGD 253
Query: 165 LEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGEL 224
L + ++Y P Q P VT+ RR+ +I A V+EDD +L
Sbjct: 254 LP----------ARADLLYLTPACQYPTTVTLGAARRQEVIRWARRSGAFVLEDDYAADL 303
Query: 225 RYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTN 284
+ G+P ++ + RVI LG+FSK LAP R G++V P + L + TD
Sbjct: 304 HWQGRPPSVLQGQAPD-RVILLGSFSKSLAPVTRSGFVVAPPEVTEVLSRTRPLTDRVPG 362
Query: 285 VFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKW--TKPEGGMFVW 342
V + ++ G RH+ + R R A+L AL +P+ W G+ ++
Sbjct: 363 VLDALALADVLASGAYTRHLRRARALLAHRGGALLTALRTELPQ---WEALPARAGLHLY 419
Query: 343 VTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
V LP G D + +L A + GVA P + A + + L F ++ + +R V+RL
Sbjct: 420 VRLPPGSDEQAILASAARLGVALSPARSGEA--GGEPAVLLAFGHLSPEALRRAVRRL 475
>gi|6321929 aromatic amino acid aminotransferase II; Aro9p [Saccharomyces
cerevisiae] >gi|626659|pir||S48981 hypothetical protein
YHR137w - yeast (Saccharomyces cerevisiae)
>gi|500670|gb|AAB68403.1|AAB68403 (U10398) Aro9p:
Aromatic amino acid aminotransferase II [Saccharomyces
cerevisiae]
Length = 513
Score = 123 bits (306), Expect = 3e-27
Identities = 125/500 (25%), Positives = 210/500 (42%), Gaps = 106/500 (21%)
Query: 7 SMLGNVERFFSKKAMEMKASEVRELLKLVETSDI----ISLAGGLPNPKTFPKEIIKEIL 62
S+ N + F S++ E R L + SDI I LAGG+PN + FP E + +
Sbjct: 13 SLKKNFQPFLSRRV------ENRSLKSFWDASDISDDVIELAGGMPNERFFPIESMDLKI 66
Query: 63 IEI------------MEEHAD----------KALQYGTTKGFTPLRETLLDWLEK--RYG 98
++ H D ++ QY TKG PL + D++ + R
Sbjct: 67 SKVPFNDNPKWHNSFTTAHLDLGSPSELPIARSFQYAETKGLPPLLHFVKDFVSRINRPA 126
Query: 99 ISKEN----DIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP 154
S E D++++ GS ++ + D V++E T+ A+ K I +
Sbjct: 127 FSDETESNWDVILSGGSNDSMFKVFETICDESTTVMIEEFTFTPAMSNVEATGAKVIPIK 186
Query: 155 L------DDNGMNVEALEDELRKLKA----EGKKVKIVYTVPTFQNPAGVTMSEERRKHL 204
+ + G++VE L L + K +++YT+ T QNP G+++ + +R+ +
Sbjct: 187 MNLTFDRESQGIDVEYLTQLLDNWSTGPYKDLNKPRVLYTIATGQNPTGMSVPQWKREKI 246
Query: 205 IELASEYDLIVIEDDPYGELRY-SGKPK-----------------------KKIKALDKE 240
+LA +D +++EDDPYG L + S P+ K LD +
Sbjct: 247 YQLAQRHDFLIVEDDPYGYLYFPSYNPQEPLENPYHSSDLTTERYLNDFLMKSFLTLDTD 306
Query: 241 GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAW---KYVSE 297
RVI L TFSKI APG R+ +IV + +++K+ T + Q + + K ++E
Sbjct: 307 ARVIRLETFSKIFAPGLRLSFIVANKFLLQKILDLADITTRAPSGTSQAIVYSTIKAMAE 366
Query: 298 GHLD--------------RHIPKIREFYKPRRDAMLEAL---EEFMPENVKWTKPEGGMF 340
+L R I +I Y R++ L+AL E + +P GMF
Sbjct: 367 SNLSSSLSMKEAMFEGWIRWIMQIASKYNHRKNLTLKALYETESYQAGQFTVMEPSAGMF 426
Query: 341 VWV-----------TLPDGID--SKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTY 387
+ + LP +D K +L+ VK + Y + + +RL Y
Sbjct: 427 IIIKINWGNFDRPDDLPQQMDILDKFLLKNGVKVVLGYKMAVCPNYSKQNSDFLRLTIAY 486
Query: 388 V-DEDKIREGVKRLAETIKE 406
D+D++ E KR+ IKE
Sbjct: 487 ARDDDQLIEASKRIGSGIKE 506
>sp|P38840|ARO9_YEAST AROMATIC AMINO ACID AMINOTRANSFERASE II >gi|2231068|emb|CAA73950.1|
(Y13625) aromatic amino acid aminotransferase II
[Saccharomyces cerevisiae]
Length = 513
Score = 123 bits (306), Expect = 3e-27
Identities = 125/500 (25%), Positives = 210/500 (42%), Gaps = 106/500 (21%)
Query: 7 SMLGNVERFFSKKAMEMKASEVRELLKLVETSDI----ISLAGGLPNPKTFPKEIIKEIL 62
S+ N + F S++ E R L + SDI I LAGG+PN + FP E + +
Sbjct: 13 SLKKNFQPFLSRRV------ENRSLKSFWDASDISDDVIELAGGMPNERFFPIESMDLKI 66
Query: 63 IEI------------MEEHAD----------KALQYGTTKGFTPLRETLLDWLEK--RYG 98
++ H D ++ QY TKG PL + D++ + R
Sbjct: 67 SKVPFNDNPKWHNSFTTAHLDLGSPSELPIARSFQYAETKGLPPLLHFVKDFVSRINRPA 126
Query: 99 ISKEN----DIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP 154
S E D++++ GS ++ + D V++E T+ A+ K I +
Sbjct: 127 FSDETESNWDVILSGGSNDSMFKVFETICDESTTVMIEEFTFTPAMSNVEATGAKVIPIK 186
Query: 155 L------DDNGMNVEALEDELRKLKA----EGKKVKIVYTVPTFQNPAGVTMSEERRKHL 204
+ + G++VE L L + K +++YT+ T QNP G+++ + +R+ +
Sbjct: 187 MNLTFDRESQGIDVEYLTQLLDNWSTGPYKDLNKPRVLYTIATGQNPTGMSVPQWKREKI 246
Query: 205 IELASEYDLIVIEDDPYGELRY-SGKPK-----------------------KKIKALDKE 240
+LA +D +++EDDPYG L + S P+ K LD +
Sbjct: 247 YQLAQRHDFLIVEDDPYGYLYFPSYNPQEPLENPYHSSDLTTERYLNDFLMKSFLTLDTD 306
Query: 241 GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAW---KYVSE 297
RVI L TFSKI APG R+ +IV + +++K+ T + Q + + K ++E
Sbjct: 307 ARVIRLETFSKIFAPGLRLSFIVANKFLLQKILDLADITTRAPSGTSQAIVYSTIKAMAE 366
Query: 298 GHLD--------------RHIPKIREFYKPRRDAMLEAL---EEFMPENVKWTKPEGGMF 340
+L R I +I Y R++ L+AL E + +P GMF
Sbjct: 367 SNLSSSLSMKEAMFEGWIRWIMQIASKYNHRKNLTLKALYETESYQAGQFTVMEPSAGMF 426
Query: 341 VWV-----------TLPDGID--SKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTY 387
+ + LP +D K +L+ VK + Y + + +RL Y
Sbjct: 427 IIIKINWGNFDRPDDLPQQMDILDKFLLKNGVKLVLGYKMAVCPNYSKQNSDFLRLTIAY 486
Query: 388 V-DEDKIREGVKRLAETIKE 406
D+D++ E KR+ IKE
Sbjct: 487 ARDDDQLIEASKRIGSGIKE 506
>pir||C33496 hisC homolog - Bacillus subtilis
Length = 393
Score = 123 bits (305), Expect = 4e-27
Identities = 113/399 (28%), Positives = 185/399 (46%), Gaps = 34/399 (8%)
Query: 12 VERFFSKKAMEMKASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHA 70
+E + KA E++ S +R+ LV + D+ISL G P+ F +K + ++E+
Sbjct: 1 MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPD--FFTPHHVKAAAKKAIDENV 58
Query: 71 DKALQYGTTKGFTPLRETLLDWLEKR--YGISKENDIMITSGSQQALDLIGRVFIDPGDI 128
Y G+ LR+ + +++K+ + E++I+IT+G+ QA+D R + PGD
Sbjct: 59 TS---YTPNAGYLELRQAVQLYMKKKADFNYDAESEIIITTGASQAIDAAFRTILSPGDE 115
Query: 129 VIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEA--LEDELRKLKAEGKKVKIVYTVP 186
VI+ P Y N K + V +G + A +ED L K V +P
Sbjct: 116 VIMPGPIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALT------PNTKCV-VLP 168
Query: 187 TFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYL 246
NP GVT+SEE K + L ++ V+ D+ Y EL Y +P I ++ ++
Sbjct: 169 YPSNPTGVTLSEEELKSIAALLKGRNVFVLSDEIYSELTYD-RPHYSIATYLRDQTIVIN 227
Query: 247 GTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK 306
G G+RIG++ I + + Q C + Q A + V+ G D I
Sbjct: 228 GLSKSHTMTGWRIGFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGFDDALI-- 285
Query: 307 IREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GID----SKKMLEKAVKK 361
+RE YK R D + + L + + KP G +++ ++ G+ S +LE A
Sbjct: 286 MREQYKKRLDYVYDRL---VSMGLDVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDA--- 339
Query: 362 GVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
GVA VPG +F Y + +RL+F D +REG+ RL
Sbjct: 340 GVALVPGSSFSTYGE--GYVRLSFA-CSMDTLREGLDRL 375
>sp|Q60317|AAT1_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 1 (TRANSAMINASE A) (ASPAT)
>gi|2127774|pir||A64300 aspartate transaminase (EC
2.6.1.1) - Methanococcus jannaschii
>gi|1592252|gb|AAB97984.1| (U67459) aspartate
aminotransferase (aspB1) [Methanococcus jannaschii]
Length = 375
Score = 122 bits (304), Expect = 6e-27
Identities = 114/402 (28%), Positives = 191/402 (47%), Gaps = 45/402 (11%)
Query: 17 SKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQY 76
S + +K S +RE+ L TSD I+L G P+ T PK II E A +AL
Sbjct: 3 SSRCKNIKPSAIREIFNLA-TSDCINLGIGEPDFDT-PKHII---------EAAKRALDE 51
Query: 77 GTT-----KGFTPLRETLLDWLEKRYGISKEND-IMITSGSQQALDLIGRVFIDPGDIVI 130
G T G LRE + + L+ Y + + D I++T G+ +AL L ID GD V+
Sbjct: 52 GKTHYSPNNGIPELREEISNKLKDDYNLDVDKDNIIVTCGASEALMLSIMTLIDRGDEVL 111
Query: 131 VEAPTYLAALQAFNFYEPKYIQVPLDDN-GMNVEALEDELRKLKAEGKKVKIVYTVPTFQ 189
+ P++++ F E K + LD+N +++E +++ + K K I++ P+
Sbjct: 112 IPNPSFVSYFSLTEFAEGKIKNIDLDENFNIDLEKVKESITK-----KTKLIIFNSPS-- 164
Query: 190 NPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTF 249
NP G +E K L E+A +Y+LI++ D+ Y ++ Y KK + R I + F
Sbjct: 165 NPTGKVYDKETIKGLAEIAEDYNLIIVSDEVYDKIIYD---KKHYSPMQFTDRCILINGF 221
Query: 250 SKILA-PGFRIGWIVGDPGIIRKLEIAK------QSTDLCTNVFGQVVAWKYVSEGHLDR 302
SK A G+RIG++ + ++L++ Q + C F Q A + G
Sbjct: 222 SKTYAMTGWRIGYLAVSDELNKELDLINNMIKIHQYSFACATTFAQYGALAAL-RGSQKC 280
Query: 303 HIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKG 362
+REF K RRD + L++ N KP+G +++ + + D ++ +K ++
Sbjct: 281 VEDMVREF-KMRRDLIYNGLKDIFKVN----KPDGAFYIFPDVSEYGDGVEVAKKLIENK 335
Query: 363 VAYVPGEAFYAYRDVKNTMRLNFT--YVDEDKIREGVKRLAE 402
V VPG AF + N +R ++ Y D +K +K + E
Sbjct: 336 VLCVPGVAF--GENGANYIRFSYATKYEDIEKALGIIKEIFE 375
>gb|AAD04762.1| (U95370) unknown protein [Bacillus licheniformis]
Length = 352
Score = 122 bits (302), Expect = 1e-26
Identities = 80/276 (28%), Positives = 135/276 (47%), Gaps = 9/276 (3%)
Query: 40 IISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGI 99
+I + P+P FP + + + ++ + + YGT KG L E + L
Sbjct: 80 VIDFSASAPDPDVFPYIDFQHCINKAIDTYKNDLFIYGTPKGLPSLIEAIQKELANGQVF 139
Query: 100 SKENDIMITSGSQQALDLIGRV-FIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDN 158
+KE I ITSG QQAL L+ + F + +++E P+Y +Q + I +
Sbjct: 140 AKEEHIFITSGVQQALALLASMPFPNRKRKILIEQPSYHLLIQYLEVHGIPAIGIERTAE 199
Query: 159 GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIED 218
G++++ LE + + +K YT+P F NP G + +E + +++LA +YD+ + ED
Sbjct: 200 GIDMDELEQIFQT-----EDIKFFYTMPRFHNPLGTSYTEREKMAIVKLAEKYDVYIAED 254
Query: 219 DPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQS 278
D G+L + K + D VIYL +FSKI PG R+G V + KQ
Sbjct: 255 DFLGDLE-NHKKADPLHYYDVSSHVIYLKSFSKIF-PGLRVGAAVLPDSLTDVFNRYKQL 312
Query: 279 TDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPR 314
D+ +++ Q AW+ + E +++H KIR Y+ R
Sbjct: 313 LDIDSSMLSQ-AAWRSIEERDVEKHKQKIRSSYQKR 347
>pir||T36822 probable transcription regulator - Streptomyces coelicolor
>gi|3581842|emb|CAA20798.1| (AL031541) putative
transcriptional regulator [Streptomyces coelicolor
A3(2)]
Length = 480
Score = 120 bits (297), Expect = 4e-26
Identities = 104/389 (26%), Positives = 165/389 (41%), Gaps = 28/389 (7%)
Query: 38 SDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRY 97
S ++ GG +P P+ + L A +G LRE W +
Sbjct: 102 SGVVEFNGGYLHPSLQPERAMAAALARAGRRPG--AWGRPPMEGLPELRE----WFARGI 155
Query: 98 GIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLD 156
G + +++IT+G Q AL R PG V+VE+PTY L + + VP+D
Sbjct: 156 GGAITAAEVLITAGGQSALATALRALAPPGTPVLVESPTYPGMLAIARAAGLRPVPVPVD 215
Query: 157 DNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVI 216
+G+ L D R A G +V + P FQNP G ++ ERR ++ +A V+
Sbjct: 216 ADGVRPALLADAFR---ATGARVFVCQ--PLFQNPTGAVLAPERRGEVLRIARAAGAFVV 270
Query: 217 EDDPYGELRY--SGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEI 274
EDD L + +G + A D +G V+++ + +K +P FR+ + ++ +L
Sbjct: 271 EDDFVRRLVHEDAGPLPAPLAADDPDGVVVHVCSLTKATSPSFRVSALAARGPVLERLRA 330
Query: 275 AKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTK 334
+ Q A + V RH+ + K RRDAM AL +PE
Sbjct: 331 IQIVDTFFVPRPLQEAALELVGSPAWPRHLRAVSAELKARRDAMTSALRLNLPEMSLAHV 390
Query: 335 PEGGMFVWVTLPDGI-------------DSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTM 381
P GG +W LP+G + A++ GVA PG +++ +
Sbjct: 391 PSGGYHLWPRLPEGTGGTGGTPQAFGSGGEAALTSAALRAGVAITPGRPYFSAEPPAAHV 450
Query: 382 RLNFTYV-DEDKIREGVKRLAETIKEETG 409
RL+F V + +I EGV+RL +E G
Sbjct: 451 RLSFAAVANVGEIAEGVRRLRTACQEVWG 479
>gb|AAK41178.1| Aspartate aminotransferase (aspB-2) [Sulfolobus solfataricus]
Length = 402
Score = 120 bits (297), Expect = 4e-26
Identities = 104/405 (25%), Positives = 196/405 (47%), Gaps = 32/405 (7%)
Query: 10 GNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEH 69
GN+ + + + K E+ ++ + II G P+ TF + + + +E
Sbjct: 9 GNMSQVTGETTLLYK--EIARNVEKTKKIKIIDFGIGQPDLPTFKR------IRDAAKEA 60
Query: 70 ADKALQYGTTK-GFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGD 127
D+ + T+ G LRE + +L RYG K+ ++++T G++ AL L+ ++I+P D
Sbjct: 61 LDQGFTFYTSAFGIDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSD 120
Query: 128 IVIVEAPTYLAALQAFNFYEPKYIQVPLD---DNGMNVEALEDELRKLKAEGKKVKIVYT 184
VI+ P++ + + K I L + G +++ D+L+ ++ K+ IV+
Sbjct: 121 EVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDV--DDLQSKISKRTKM-IVFN 177
Query: 185 VPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVI 244
P NP G S K +++++ + +I++ D+ Y Y GK + ++ D +I
Sbjct: 178 NP--HNPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLI 235
Query: 245 YLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRH 303
Y+ FSK + G+R+G+IV II+K+ I + F Q A K
Sbjct: 236 YVNGFSKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFD---E 292
Query: 304 IPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVW-----VTLPDGIDSKKMLEKA 358
+ ++ +K RRD M + L + + V+ +KP G +++ + G D K + K
Sbjct: 293 VNQMVSLFKKRRDVMYDELTKV--KGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKL 350
Query: 359 V-KKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
+ +KGV +PGE F K +RL+F V+E+ I+EG++++ E
Sbjct: 351 IEEKGVVTIPGEVF-PLNIGKEFLRLSFA-VNEEVIKEGIQKIRE 393
>sp|P14909|AAT_SULSO ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|99262|pir||S07088 aspartate transaminase (EC
2.6.1.1) - Sulfolobus solfataricus
>gi|809765|emb|CAA34514.1| (X16505) aspartate
aminotransferase (AA 1-402) [Sulfolobus solfataricus]
>gi|226717|prf||1604198A Asp aminotransferase
[Sulfolobus solfataricus]
Length = 402
Score = 120 bits (297), Expect = 4e-26
Identities = 104/405 (25%), Positives = 196/405 (47%), Gaps = 32/405 (7%)
Query: 10 GNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEH 69
GN+ + + + K E+ ++ + II G P+ TF + + + +E
Sbjct: 9 GNMSQVTGETTLLYK--EIARNVEKTKKIKIIDFGIGQPDLPTFKR------IRDAAKEA 60
Query: 70 ADKALQYGTTK-GFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGD 127
D+ + T+ G LRE + +L RYG K+ ++++T G++ AL L+ ++I+P D
Sbjct: 61 LDQGFTFYTSAFGIDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSD 120
Query: 128 IVIVEAPTYLAALQAFNFYEPKYIQVPLD---DNGMNVEALEDELRKLKAEGKKVKIVYT 184
VI+ P++ + + K I L + G +++ D+L+ ++ K+ IV+
Sbjct: 121 EVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDV--DDLQSKISKRTKM-IVFN 177
Query: 185 VPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVI 244
P NP G S K +++++ + +I++ D+ Y Y GK + ++ D +I
Sbjct: 178 NP--HNPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLI 235
Query: 245 YLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRH 303
Y+ FSK + G+R+G+IV II+K+ I + F Q A K
Sbjct: 236 YVNGFSKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFD---E 292
Query: 304 IPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVW-----VTLPDGIDSKKMLEKA 358
+ ++ +K RRD M + L + + V+ +KP G +++ + G D K + K
Sbjct: 293 VNQMVSLFKKRRDVMYDELTKV--KGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKL 350
Query: 359 V-KKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
+ +KGV +PGE F K +RL+F V+E+ I+EG++++ E
Sbjct: 351 IEEKGVVTIPGEVF-PLNIGKEFLRLSFA-VNEEVIKEGIQKIRE 393
>pir||S45613 aspartate aminotransferase - Sulfolobus solfataricus
Length = 401
Score = 120 bits (297), Expect = 4e-26
Identities = 104/405 (25%), Positives = 196/405 (47%), Gaps = 32/405 (7%)
Query: 10 GNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEH 69
GN+ + + + K E+ ++ + II G P+ TF + + + +E
Sbjct: 8 GNMSQVTGETTLLYK--EIARNVEKTKKIKIIDFGIGQPDLPTFKR------IRDAAKEA 59
Query: 70 ADKALQYGTTK-GFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGD 127
D+ + T+ G LRE + +L RYG K+ ++++T G++ AL L+ ++I+P D
Sbjct: 60 LDQGFTFYTSAFGIDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSD 119
Query: 128 IVIVEAPTYLAALQAFNFYEPKYIQVPLD---DNGMNVEALEDELRKLKAEGKKVKIVYT 184
VI+ P++ + + K I L + G +++ D+L+ ++ K+ IV+
Sbjct: 120 EVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDV--DDLQSKISKRTKM-IVFN 176
Query: 185 VPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVI 244
P NP G S K +++++ + +I++ D+ Y Y GK + ++ D +I
Sbjct: 177 NP--HNPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLI 234
Query: 245 YLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRH 303
Y+ FSK + G+R+G+IV II+K+ I + F Q A K
Sbjct: 235 YVNGFSKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFD---E 291
Query: 304 IPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVW-----VTLPDGIDSKKMLEKA 358
+ ++ +K RRD M + L + + V+ +KP G +++ + G D K + K
Sbjct: 292 VNQMVSLFKKRRDVMYDELTKV--KGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKL 349
Query: 359 V-KKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
+ +KGV +PGE F K +RL+F V+E+ I+EG++++ E
Sbjct: 350 IEEKGVVTIPGEVF-PLNIGKEFLRLSFA-VNEEVIKEGIQKIRE 392
>pir||E71009 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PH1371
[similarity] - Pyrococcus horikoshii
>gi|3257794|dbj|BAA30477.1| (AP000006) 389aa long
hypothetical aspartate aminotransferase [Pyrococcus
horikoshii]
Length = 389
Score = 119 bits (296), Expect = 5e-26
Identities = 111/395 (28%), Positives = 190/395 (48%), Gaps = 30/395 (7%)
Query: 23 MKASEVRELLKLVE-TSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKAL-QYGTTK 80
+ ASE+R+L + D+ISL G P+ T P+ I E +E DK L YG
Sbjct: 10 VSASEIRKLFDIAAGMKDVISLGIGEPDFDT-PQHIK-----EYAKEALDKGLTHYGPNI 63
Query: 81 GFTPLRETLLDWLEKRYGISKE--NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLA 138
G LRE + + L+K+ GI + +IM+ G+ QA + F+ G+ V++ P +++
Sbjct: 64 GLLELREAIAEKLKKQNGIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFVS 123
Query: 139 ALQAFNFYEPKYIQVPL---DDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVT 195
A K ++VP D+ +NV DEL+K + + I+ + NP G
Sbjct: 124 YAPAVILAGGKPVEVPTYEEDEFRLNV----DELKKYVTDKTRALIINSPC---NPTGAV 176
Query: 196 MSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALD-KEGRVIYLGTFSKILA 254
++++ + + + E+DLIVI D+ Y Y I +LD R I + FSK A
Sbjct: 177 LTKKDLEEIADFVVEHDLIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFSKTFA 236
Query: 255 -PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKP 313
G+R+G++ II ++ + C F Q A K + + + + ++R+ Y
Sbjct: 237 MTGWRLGFVAAPSWIIERMVKFQMYNATCPVTFIQYAAAKALKDERSWKAVEEMRKEYDR 296
Query: 314 RRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKG-VAYVPGEAF 371
RR + + L E + KP+G +++ + D G+ SKK E +K+ VA VPG AF
Sbjct: 297 RRKLVWKRLNEM---GLPTVKPKGAFYIFPRIRDTGLTSKKFSELMLKEARVAVVPGSAF 353
Query: 372 YAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
+ + +R+++ E K+ E + R+ +KE
Sbjct: 354 --GKAGEGYVRISYATAYE-KLEEAMDRMERVLKE 385
>pir||C69672 probable aspartate transaminase (EC 2.6.1.-) patA [similarity] -
Bacillus subtilis >gi|2633771|emb|CAB13273.1| (Z99111)
aminotransferase [Bacillus subtilis]
Length = 392
Score = 118 bits (292), Expect = 1e-25
Identities = 113/399 (28%), Positives = 185/399 (46%), Gaps = 35/399 (8%)
Query: 12 VERFFSKKAMEMKASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHA 70
+E + KA E++ S +R+ LV + D+ISL G P+ F +K + ++E+
Sbjct: 1 MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPD--FFTPHHVKAAAKKAIDENV 58
Query: 71 DKALQYGTTKGFTPLRETLLDWLEKR--YGISKENDIMITSGSQQALDLIGRVFIDPGDI 128
Y G+ LR+ + +++K+ + E++I+IT+G+Q A+D R + PGD
Sbjct: 59 TS---YTPNAGYLELRQAVQLYMKKKADFNYDAESEIIITTGAQ-AIDAAFRTILSPGDE 114
Query: 129 VIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEA--LEDELRKLKAEGKKVKIVYTVP 186
VI+ P Y N K + V +G + A +ED L K V +P
Sbjct: 115 VIMPGPIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTP------NTKCV-VLP 167
Query: 187 TFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYL 246
NP GVT+SEE K + L ++ V+ D+ Y EL Y +P I ++ ++
Sbjct: 168 YPSNPTGVTLSEEELKSIAALLKGRNVFVLSDEIYSELTYD-RPHYSIATYLRDQTIVIN 226
Query: 247 GTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK 306
G G+RIG++ I + + Q C + Q A + V+ G D I
Sbjct: 227 GLSKSHSMTGWRIGFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGFDDALI-- 284
Query: 307 IREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GID----SKKMLEKAVKK 361
+RE YK R D + + L + + KP G +++ ++ G+ S +LE A
Sbjct: 285 MREQYKKRLDYVYDRL---VSMGLDVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDA--- 338
Query: 362 GVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
GVA VPG +F Y + +RL+F D +REG+ RL
Sbjct: 339 GVALVPGSSFSTYGE--GYVRLSFA-CSMDTLREGLDRL 374
>pir||E71125 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PH0771
[similarity] - Pyrococcus horikoshii
>gi|3257180|dbj|BAA29863.1| (AP000003) 391aa long
hypothetical aspartate aminotransferase [Pyrococcus
horikoshii]
Length = 391
Score = 118 bits (292), Expect = 1e-25
Identities = 102/405 (25%), Positives = 202/405 (49%), Gaps = 34/405 (8%)
Query: 15 FFSKKAMEMKASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKA 73
F +++ + +K S++REL + + D+ISL G P+ T PK I +E A +A
Sbjct: 8 FIAERVLLIKRSKIRELFERASKMEDVISLGIGEPDFDT-PKNI---------KEAAKRA 57
Query: 74 LQYGTTK-----GFTPLRETLLDWLEKRYGISKE-NDIMITSGSQQALDLIGRVFIDPGD 127
L G T G LRE ++++ +K YGI E +++IT+G+ + L ++ GD
Sbjct: 58 LDEGWTHYTPNAGIPELREAVVEYYKKFYGIDIEVENVIITAGAYEGTYLAFESLLERGD 117
Query: 128 IVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPT 187
VI+ P +++ + E K +++PL + + + L K+ + + I Y
Sbjct: 118 EVIIPDPAFVSYAEDAKVAEAKPVRIPLREENNFLPDPNELLEKISKNTRMIVINYP--- 174
Query: 188 FQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLG 247
NP G T+ +E K + ++A +Y++ ++ D+PY Y + E ++
Sbjct: 175 -NNPTGATLDKELAKTIADIAEDYNIYILSDEPYEHFIYEDAKHYPMIKFAPENTIL-AN 232
Query: 248 TFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNV--FGQVVAWKYVSEGHLDRHI 304
+FSK A G+R+G++V +I+ E+ K + NV F Q+ + + + +
Sbjct: 233 SFSKTFAMTGWRLGFVVAPSQVIK--EMTKLHAYVIGNVASFVQIAGIEALRSEESWKAV 290
Query: 305 PKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLP-DGIDSKKMLEKAVKKG- 362
++++ Y RR +++ L+ MP +K +P+G +V+ + G+ S+K E ++K
Sbjct: 291 EEMKKEYNERRKIVVKRLKN-MP-GIKVKEPKGAFYVFPNISGTGMSSEKFSEWLLEKAR 348
Query: 363 VAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
V +PG AF R + +R+++ ++K+ E + R+ + ++ E
Sbjct: 349 VVVIPGTAF--GRMGEGYVRISYA-TSKEKLIEAMNRIEKALEGE 390
>sp|P16524|PATA_BACSU PUTATIVE AMINOTRANSFERASE A >gi|2632221|emb|CAA10863.1| (AJ222587)
PatA protein [Bacillus subtilis]
Length = 392
Score = 117 bits (290), Expect = 3e-25
Identities = 113/399 (28%), Positives = 185/399 (46%), Gaps = 35/399 (8%)
Query: 12 VERFFSKKAMEMKASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHA 70
+E + KA E++ S +R+ LV + D+ISL G P+ F +K + ++E+
Sbjct: 1 MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPD--FFTPHHVKAAAKKAIDENV 58
Query: 71 DKALQYGTTKGFTPLRETLLDWLEKR--YGISKENDIMITSGSQQALDLIGRVFIDPGDI 128
Y G+ LR+ + +++K+ + E++I+IT+G+Q A+D R + PGD
Sbjct: 59 TS---YTPNAGYLELRQAVQLYMKKKADFNYDAESEIIITTGAQ-AIDAAFRTILSPGDE 114
Query: 129 VIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEA--LEDELRKLKAEGKKVKIVYTVP 186
VI+ P Y N K + V +G + A +ED L K V +P
Sbjct: 115 VIMPGPIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTP------NTKCV-VLP 167
Query: 187 TFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYL 246
NP GVT+SEE K + L ++ V+ D+ Y EL Y +P I ++ ++
Sbjct: 168 YPSNPTGVTLSEEELKSIAALLKGRNVFVLSDEIYSELTYD-RPHYSIATYLRDQTIVIN 226
Query: 247 GTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK 306
G G+RIG++ I + + Q C + Q A + V+ G D I
Sbjct: 227 GLSKSHSMTGWRIGFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGLDDALI-- 284
Query: 307 IREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GID----SKKMLEKAVKK 361
+RE YK R D + + L + + KP G +++ ++ G+ S +LE A
Sbjct: 285 MREQYKKRLDYVYDRL---VSMGLDVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDA--- 338
Query: 362 GVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
GVA VPG +F Y + +RL+F D +REG+ RL
Sbjct: 339 GVALVPGSSFSTYGE--GYVRLSFA-CSMDTLREGLDRL 374
>pir||G75037 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PAB1523
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5458709|emb|CAB50196.1| (AJ248287) aspartate
aminotransferase (aspB-2) [Pyrococcus abyssi]
Length = 390
Score = 116 bits (289), Expect = 3e-25
Identities = 103/399 (25%), Positives = 203/399 (50%), Gaps = 24/399 (6%)
Query: 15 FFSKKAMEMKASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKA 73
F +++ + +K S++REL + + ++ISL G P+ T PK I KE ++E
Sbjct: 8 FIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDT-PKNI-KEACKRALDEGWT-- 63
Query: 74 LQYGTTKGFTPLRETLLDWLEKRYGISKE-NDIMITSGSQQALDLIGRVFIDPGDIVIVE 132
Y G LRE ++++ +K Y + + +++IT+G+ + L ++ GD V++
Sbjct: 64 -HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIP 122
Query: 133 APTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPA 192
P +++ ++ E K +++PL + N DEL +L + ++ IV P NP
Sbjct: 123 DPAFVSYVEDAKLAEAKPVRIPLREEN-NFMPDPDELLELVTKKTRM-IVINYPN--NPT 178
Query: 193 GVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKI 252
G T+ +E K + ++A +Y++ ++ D+PY Y + E ++ +FSK
Sbjct: 179 GATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKT 237
Query: 253 LA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNV--FGQVVAWKYVSEGHLDRHIPKIRE 309
A G+R+G++V II+ E+ K + NV F QV + + + + ++R+
Sbjct: 238 FAMTGWRLGFVVAPSEIIK--EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRK 295
Query: 310 FYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKG-VAYVP 367
Y RR +L+ L+E MP ++ +P+G +V+ ++ D G+ S+K E ++K V +P
Sbjct: 296 EYNERRKLVLKRLKE-MP-GIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIP 353
Query: 368 GEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
G AF + +R+++ +K+ E + R+ + + E
Sbjct: 354 GTAFGKMGE--GYVRISYA-TSREKLMEAMDRMEKALSE 389
>emb|CAB89055.1| (AL353872) putative gntR-family regulator [Streptomyces coelicolor
A3(2)]
Length = 462
Score = 115 bits (285), Expect = 1e-24
Identities = 91/323 (28%), Positives = 149/323 (45%), Gaps = 17/323 (5%)
Query: 43 LAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKE 102
L G P+ +FP+ + ++A YG +G LR L +L + G+
Sbjct: 110 LRPGSPDLASFPRVEWLRAARRAVTAAPNEAFGYGDPRGHPELRGALSAYLARARGVRAA 169
Query: 103 ND-IMITSGSQQALDLIGRVFIDPG-DIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGM 160
D ++I G AL ++ V G V VE+ + + +P+DD G
Sbjct: 170 PDHLLICGGVAHALVVLAAVLRARGVRTVAVESYGLHVHRDLLEAAGLRTVPLPVDDRGA 229
Query: 161 NVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDP 220
+ AL D V P Q P GV + +RR +++ A +++EDD
Sbjct: 230 DPGALTD-----------AGAVLLTPAHQFPTGVPLHPDRRAAVVDWARRTGALILEDDY 278
Query: 221 YGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTD 280
GE RY +P ++ L + V+YLGT SK LAPG R+ W V PG+ ++ + +D
Sbjct: 279 DGEFRYDRQPVGALQGLAPD-HVVYLGTASKSLAPGLRLAWAVLPPGLADEITATRGGSD 337
Query: 281 LCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMF 340
C V Q+ ++++ G DRH+ R Y+ RRDA++ AL +PE V+ G+
Sbjct: 338 TC-GVLEQLTLAEFLASGAYDRHVRASRLRYRRRRDALVAALAGRVPE-VRIAGIAAGLH 395
Query: 341 VWVTLPDGIDSKKMLEKAVKKGV 363
+ LP G + +++L A +G+
Sbjct: 396 AVLGLPPGTE-QQVLRSAAWQGL 417
>pir||B75122 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PAB0525
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5458202|emb|CAB49691.1| (AJ248285) aspartate
aminotransferase (aspC) [Pyrococcus abyssi]
Length = 389
Score = 111 bits (276), Expect = 1e-23
Identities = 107/391 (27%), Positives = 186/391 (47%), Gaps = 26/391 (6%)
Query: 26 SEVRELLKLVE-TSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKAL-QYGTTKGFT 83
SE+R+L + D+ISL G P+ T P+ I E +E D L YG G
Sbjct: 13 SEIRKLFDIAAGMKDVISLGIGEPDFDT-PQHIK-----EYAKEALDMGLTHYGPNIGLP 66
Query: 84 PLRETLLDWLEKRYGISKE--NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQ 141
LRE + + L+K+ I + +IM+ G+ QA + F+ G+ V++ P +++
Sbjct: 67 ELREAIAEKLKKQNNIEADPNKEIMVLVGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAP 126
Query: 142 AFNFYEPKYIQVPL-DDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEER 200
A K ++VP ++N + DEL+K E K I+ + NP G + ++
Sbjct: 127 AVILAGGKPVEVPTYEENEFRLNV--DELKKYVTEKTKALIINSPC---NPTGSVLKKKD 181
Query: 201 RKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALD-KEGRVIYLGTFSKILA-PGFR 258
+ + + A E+DLIVI D+ Y Y I +LD R I + FSK A G+R
Sbjct: 182 LEEIADFAVEHDLIVISDEVYEHFIYDDVKHYSIASLDGMFERTITVNGFSKTFAMTGWR 241
Query: 259 IGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAM 318
+G++ II K+ + C F Q A K + + + + ++R+ Y RR +
Sbjct: 242 LGFVAAPSWIIEKMVKFQMYNATCPVTFIQYAAAKALRDERSWKAVEEMRKEYDRRRKLV 301
Query: 319 LEALEEFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKG-VAYVPGEAFYAYRD 376
+ L E + KP+G +++ + D G+ SK+ E + + VA VPG AF +
Sbjct: 302 WKRLNEM---GLPTVKPKGAFYIFPRIKDTGLTSKEFSELMLMEAKVAVVPGSAF--GKA 356
Query: 377 VKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
+ +R+++ E K+ E + R+ + ++E+
Sbjct: 357 GEGYVRISYATAYE-KLEEAMDRMEKVLREK 386
>gb|AAF01064.1|AF189258_3 (AF189258) transcriptional regulator [Streptomyces venezuelae]
Length = 507
Score = 111 bits (275), Expect = 1e-23
Identities = 97/342 (28%), Positives = 148/342 (42%), Gaps = 13/342 (3%)
Query: 43 LAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKE 102
L G N FP+ +++ Y G LR L +L + G+ +
Sbjct: 97 LRAGGRNLPAFPRREWLSCYQRVLDAATPADHDYPPPAGEPALRTELAHYLGRSRGVRAD 156
Query: 103 -NDIMITSGSQQALDLIGRVFIDPG-DIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGM 160
IM+ +G AL L+ V G D + +E P + + + VP+D+ G+
Sbjct: 157 AGTIMVVAGFGHALGLLCSVLPWHGVDRLAIEDPGHPGQRRFLGESGLTPVPVPVDEEGI 216
Query: 161 NVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDP 220
+VEAL A G + +V P Q P GVT+S RR+ L+ A VIEDD
Sbjct: 217 DVEALA-------ATGARAVLV--TPAHQFPTGVTLSARRREALVRWARAVGGWVIEDDY 267
Query: 221 YGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTD 280
G L Y P+ RV+Y GT SK LAPG R+GW+ ++ L + D
Sbjct: 268 DGGLWYERTPRPPALQRLAPDRVLYAGTASKTLAPGLRLGWLAVPGELVEPLLRGRARHD 327
Query: 281 LCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMF 340
L T Q+ + + G DRH+ ++ + RR+A+ EA+ +P V T G
Sbjct: 328 LGTETLTQLAFAELLRGGMFDRHLRRLNAHCRGRREALDEAVRRHLPGAVV-TGRAAGHH 386
Query: 341 VWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMR 382
++ LP D ++ A+ + V V G A Y R ++ R
Sbjct: 387 AYLRLPRHADEAALVSAALGRSV-LVRGAAAYHARPLRGAAR 427
>gb|AAF06954.1|AF146529_1 (AF146529) aromatic amino acid aminotransferase [Lactococcus lactis
subsp. cremoris]
Length = 391
Score = 111 bits (274), Expect = 2e-23
Identities = 102/405 (25%), Positives = 187/405 (45%), Gaps = 31/405 (7%)
Query: 16 FSKKAMEMKASEVRELLKLVET-SDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKAL 74
F+ +++ S +R+ + V + DII L G P + E +K+ I +E +
Sbjct: 7 FNPNLDKIEISLIRQFDQQVSSIPDIIKLTLG--EPDFYTPEHVKQAGIAAIENNQS--- 61
Query: 75 QYGTTKGFTPLRETLLDWLEKRYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVIVE 132
Y G LR+ ++L K+YG+S E++I++T G +A+ + + GD V++
Sbjct: 62 HYTGMAGLLELRQAASEFLLKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLIP 121
Query: 133 APTY-----LAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPT 187
AP Y L L + E I +D + E L+ + ++ EGK ++ P
Sbjct: 122 APAYPGYEPLITLAGGSLVE---IDTRANDFVLTPEMLDQAI--IEREGKVKAVILNYPA 176
Query: 188 FQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLG 247
NP GVT + E+ K L E+ ++++ VI D+ Y EL Y+ +P I E ++ G
Sbjct: 177 --NPTGVTYNREQIKDLAEVLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNG 234
Query: 248 TFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKI 307
G+RIG I ++ ++ Q + Q A + + G D +P
Sbjct: 235 LSKSHAMTGWRIGLIFAARELVAQIIKTHQYLVTSASTQSQFAAIEALKNG-ADDALPMK 293
Query: 308 REFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDS---KKMLEKAVKKGVA 364
+E+ K RRD ++E + K +P+G +++ +P ++ K ++ A + VA
Sbjct: 294 KEYLK-RRDYIIEKMSAL---GFKIIEPDGAFYIFAKIPADLEQDSFKFAVDFAKENAVA 349
Query: 365 YVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEETG 409
+PG AF Y + +RL++ D I + + RL + + ++ G
Sbjct: 350 IIPGIAFGQYGE--GFVRLSYA-ASMDVIEQAMARLTDYVTKKRG 391
>pir||F81432 probable transaminase (EC 2.6.1.-) Cj0150c [similarity] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967644|emb|CAB72634.1| (AL139074) aminotransferase
[Campylobacter jejuni]
Length = 400
Score = 110 bits (273), Expect = 3e-23
Identities = 107/386 (27%), Positives = 166/386 (42%), Gaps = 37/386 (9%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
DII + G PN KT P+ II ++ + DK Y T+ G LR + +W +++Y
Sbjct: 34 DIIDFSMGNPNGKT-PQHIIDKLC---ESANKDKTSGYSTSMGIYKLRLAICNWYKRKYN 89
Query: 99 IS--KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLD 156
++ EN+++ T GS++ + R I+PGD+ IV P Y QAF ++PL
Sbjct: 90 VNLDPENEVVATMGSKEGFVNLARAIINPGDVAIVPTPAYPIHTQAFIIAGGNVAKMPLA 149
Query: 157 DN---GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDL 213
N ++ + L K E V NP VT + + LI A +
Sbjct: 150 YNEKFELDENQFFENLHKTLNESIPCPKYVVVNFPHNPTTVTCEKSFYERLIATAKKERF 209
Query: 214 IVIEDDPYGELRYSGKPKKKIKALDKEGR---VIYLGTFSKIL-APGFRIGWIVGDPGII 269
+I D Y +L Y I L+ EG + T SK G+R+G++VG+ ++
Sbjct: 210 YIISDIAYADLTYDDYKTPSI--LEIEGAKDVAVETYTLSKSYNMAGWRVGFVVGNKRLV 267
Query: 270 RKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRH---IPKIREFYKPRRDAMLEALEEFM 326
L+ K D +G + + LD + +IR Y R +LEA
Sbjct: 268 SALKKIKSWFD-----YGMYTPIQVAATIALDGDQTCVDEIRATYDKRMHILLEAF---- 318
Query: 327 PENVKW--TKPEGGMFVWVTLPDGIDSKKMLEKA----VKKGVAYVPGEAFYAYRDVKNT 380
EN W KP MFVW LP+ K LE + + VA PG F D
Sbjct: 319 -ENAGWKLQKPRASMFVWAKLPESKRHLKSLEFSKQLLQRASVAVSPGVGFGEAGDEYVR 377
Query: 381 MRLNFTYVDEDKIREGVKRLAETIKE 406
+ L +E++IR+ + + + +KE
Sbjct: 378 IAL---IENENRIRQAARNIKKYLKE 400
>gb|AAG02195.1|AF286159_1 (AF286159) PdxR [Streptomyces venezuelae]
Length = 532
Score = 110 bits (273), Expect = 3e-23
Identities = 90/331 (27%), Positives = 150/331 (45%), Gaps = 13/331 (3%)
Query: 81 GFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAAL 140
G LR+ L D R + IM+T+G+ A+D I +F G+ + VE+P+Y L
Sbjct: 173 GLPALRQMLADRYTARGIPTMPEQIMVTTGAMGAIDAICHLFAGRGERIAVESPSYANIL 232
Query: 141 QAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEER 200
Q + + V + + G+ L + L+ + + Y V F NP G E++
Sbjct: 233 QLMREAGARLVPVAMSE-GLGSWDLGRWRQVLRDAAPR--LAYVVADFHNPTGALADEDQ 289
Query: 201 RKHLIELASEYDLIVIEDDPYGELRYSGKPK--KKIKALDKEGR-VIYLGTFSKILAPGF 257
R+ L++ A +++ D+ EL + + + A D G V+ +G+ SK G
Sbjct: 290 RRQLVDAARSAGTVLVVDETMAELYLDDDVEMPRPVCAFDPAGSTVLTVGSASKAFWAGM 349
Query: 258 RIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDA 317
RIGW+ P +IR L A+ DL T V Q+ + G D + R+ + RDA
Sbjct: 350 RIGWVRAAPDVIRSLVAARAYADLGTPVLEQLGVNWLMRTGGWDEAVTLRRDQARENRDA 409
Query: 318 MLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDV 377
++ A+ +PE +++ P GG+ +WV G+ ++ E + GV G F
Sbjct: 410 LVAAVRRELPE-WEFSVPRGGLTLWVR-TGGLSGSRLAEAGERVGVRVPSGPRFGVDGAF 467
Query: 378 KNTMRLNFT----YVDEDKIR-EGVKRLAET 403
+ +RL FT DE +R RL E+
Sbjct: 468 EGFVRLPFTVGGPVADEAAVRLAAAARLVES 498
>dbj|BAB04779.1| (AP001510) aspartate aminotransferase [Bacillus halodurans]
Length = 395
Score = 109 bits (270), Expect = 6e-23
Identities = 102/382 (26%), Positives = 175/382 (45%), Gaps = 41/382 (10%)
Query: 3 EEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEIL 62
E+ K M E+FF+K +V+E+ K + DII+L G P+ T E +
Sbjct: 5 EQAKMMKRLPEQFFAKLV-----EQVQEVKK--DHDDIINLGQGSPDLPT------PEHI 51
Query: 63 IEIMEEHADKAL--QYGTTKGFTPLRETLLDWLEKRYGISKE--NDIMITSGSQQALDLI 118
+E ++E A+ L +Y G+ L+E + + E+ YG+S + ++ + G++ L +
Sbjct: 52 VEKLQEAAENPLYHRYAPFSGYPFLKEAVSKYYEREYGVSVDPKTEVAVLGGAKTGLVEV 111
Query: 119 GRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKA---- 174
+ F++PGD+ +V P Y +PL +LR + A
Sbjct: 112 SQCFLNPGDMALVPDPGYPDYWSGIAIAGGSMYGMPLKKE----LGFHPDLRGIPAPVLY 167
Query: 175 EGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSG-KPKKK 233
E K + + Y NP G +EE IELA EYD+ V+ D Y + + G KP
Sbjct: 168 EAKLMFLNYP----NNPTGAVATEELFAEAIELAEEYDICVVHDFAYSAIGFDGQKPLSF 223
Query: 234 IKALDKEGRVIYLGTFSK-ILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAW 292
++ + I + T SK G+RIG+ VG+P +I+ +E Q C ++FG + A
Sbjct: 224 LQVEGAKNVGIEMITLSKNYNMAGWRIGFAVGNPSVIKAIE-TLQDHYFC-SLFGGIQAA 281
Query: 293 KYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKW--TKPEGGMFVWVTLPDGID 350
+ ++ + + Y+ RR+A+++A + W P+G F W +P G
Sbjct: 282 AAHALLSDQSNVTTLVQTYEERRNALVKAARA-----IGWDVEAPKGSFFAWFPVPSGFT 336
Query: 351 SKKMLEKAVKKG-VAYVPGEAF 371
S++ +KK V PG+ F
Sbjct: 337 SEEFATYLLKKARVVVAPGKGF 358
>pir||E70338 probable aspartate transaminase (EC 2.6.1.1) aspC3 [similarity] -
Aquifex aeolicus >gi|2983083|gb|AAC06689.1| (AE000689)
aminotransferase (AspC family) [Aquifex aeolicus]
Length = 373
Score = 109 bits (269), Expect = 7e-23
Identities = 98/375 (26%), Positives = 176/375 (46%), Gaps = 34/375 (9%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
D++ + G P+ + PK + E L ++E K Y G LRE + ++ K+Y
Sbjct: 24 DVVHMEIGEPDLEPSPK--VMEALERAVKE---KTFFYTPALGLWELRERISEFYRKKYS 78
Query: 99 ISKEND-IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFY---EPKYIQVP 154
+ + +++T+G+ A + V ++ G+ +I+ P+Y + F + +P ++ V
Sbjct: 79 VEVSPERVIVTTGTSGAFLVAYAVTLNAGEKIILPDPSY-PCYKNFAYLLDAQPVFVNVD 137
Query: 155 LDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLI 214
+ N E+RK E K ++ + + QNP G S E K L E E +
Sbjct: 138 KETNY--------EVRKEMIEDIDAKALH-ISSPQNPTGTLYSPETLKELAEYCEEKGMY 188
Query: 215 VIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLE 273
I D+ Y L Y G+ AL+ R I + FSK PGFRIGW++ ++RK E
Sbjct: 189 FISDEIYHGLVYEGREHT---ALEFSDRAIVINGFSKYFCMPGFRIGWMIVPEELVRKAE 245
Query: 274 IAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWT 333
I Q+ + Q A + +L+ K+R+ ++ RR+ + L++ +
Sbjct: 246 IVIQNVFISAPTLSQYAALEAFDYEYLE----KVRKTFEERRNFLYGELKKLFKID---A 298
Query: 334 KPEGGMFVWVTLPD-GIDSKKMLEKAVKKG-VAYVPGEAFYAYRDVKNTMRLNFTYVDED 391
KP+G +VW + D DS + K +++ VA PG F K +R +T E+
Sbjct: 299 KPQGAFYVWANISDYSTDSYEFALKLLREARVAVTPGVDF-GKNKTKEYIRFAYTRKIEE 357
Query: 392 KIREGVKRLAETIKE 406
++EGV+R+ + +++
Sbjct: 358 -LKEGVERIKKFLEK 371
>sp|O33822|AAT_THEAQ ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447805|pir||JC5775 aspartate transaminase (EC
2.6.1.1) - Thermus aquaticus >gi|2266762|emb|CAA67877.1|
(X99521) aspartate aminotransferase [Thermus aquaticus]
Length = 383
Score = 107 bits (265), Expect = 2e-22
Identities = 106/414 (25%), Positives = 184/414 (43%), Gaps = 43/414 (10%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
+ + +KSM + + +A+E++ V D+++L G P+ T
Sbjct: 4 LSQRVKSMKPSATVAVNARALELRRKGV----------DLVALTAGEPDFDT-------- 45
Query: 61 ILIEIMEEHADKALQYGTTK-----GFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQA 114
E ++E +AL G TK G LRE + + + G+ + ++T G +QA
Sbjct: 46 --PEHVKEAGRRALAQGKTKYAPPAGIPELREAVAEKFRRENGLEVTPEETIVTVGGKQA 103
Query: 115 LDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP-LDDNGMNVEALEDELRKLK 173
L + + +DPGD VIV AP +++ + F ++VP L + G + D R +
Sbjct: 104 LFNLFQAILDPGDEVIVLAPYWVSYPEMVRFAGGVPVEVPTLPEEGF----VPDPERVRR 159
Query: 174 AEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKK 233
A + K + V + NP GV EE + L E+A ++D ++ D+ Y L Y G
Sbjct: 160 AITPRTKAL-VVNSPNNPTGVVYPEEVLRALAEMALQHDFYLVSDEIYEHLIYEGAHFSP 218
Query: 234 IKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKL-EIAKQSTDLCTNVFGQVVAW 292
L E + G G+RIG+ G +I+ + +++ QST +
Sbjct: 219 -GTLAPEHTITVNGAAKAFAMTGWRIGYACGPKAVIKAMADVSSQSTTSPDTIAQWATLE 277
Query: 293 KYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWV-TLPDGIDS 351
+ I RE Y+ RRD +LE L E V +P G +V + T P +
Sbjct: 278 ALTNREASMAFIAMAREAYRKRRDLLLEGLSRIGLEAV---RPSGAFYVLMDTSPFAPNE 334
Query: 352 KKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIK 405
+ E+ + GVA VPG F A+ V RL++ E+ +++ ++R A+ ++
Sbjct: 335 VEAAERLLMAGVAVVPGTEFAAFGHV----RLSYA-TGEENLKKALERFAQALQ 383
>gi|11499943 aspartate aminotransferase (aspB-1) [Archaeoglobus fulgidus]
>gi|7447820|pir||F69545 probable aspartate transaminase
(EC 2.6.1.1) aspB1 AF2366 [similarity] - Archaeoglobus
fulgidus >gi|2650722|gb|AAB91291.1| (AE001112) aspartate
aminotransferase (aspB-1) [Archaeoglobus fulgidus]
Length = 373
Score = 107 bits (265), Expect = 2e-22
Identities = 98/394 (24%), Positives = 183/394 (45%), Gaps = 44/394 (11%)
Query: 22 EMKASEVRELLKLVETS-----DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQY 76
++ S +R + ++VE + +IISL G P+ T P+E+I E A +A+
Sbjct: 9 QISTSMIRRMFEIVERAKKEGREIISLTIGEPDFDT-PQEVI---------ERACRAMNA 58
Query: 77 GTTKGFTPLR-ETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPT 135
G T + E L + +RYG+ N +M+T+G +AL FI+ G V++ +P
Sbjct: 59 GFTHYTSNFGLEELRSAIAERYGVDSSN-VMVTAGGSEALLNASLAFIEEGSKVVIPSPN 117
Query: 136 YLAALQAFNFYEPKYIQVPLDDNGM--NVEALEDELRKLKAEGKKVKIVYTVPTFQNPAG 193
+L+ + +Q+ +NG +VE L + + + V +++ + NP G
Sbjct: 118 FLSYFTYAKMCGGQIVQLRTHNNGFLPDVEKLNEII------DRNVSVIF-LNYPNNPTG 170
Query: 194 VTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKIL 253
+ E+ + ++E+A++ IV+ D+ Y ++ Y KP +L V+ + FSK L
Sbjct: 171 AVIDEKDARAVVEIAADNKAIVVSDEIYDQIYYDVKP----TSLAGYENVVCVNGFSKSL 226
Query: 254 A-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYK 312
+ G+RIG+ + D ++ + Q +C F Q + ++E D + ++ + ++
Sbjct: 227 SMTGWRIGFTIADEKLLDPMLKVHQVNGVCAPAFAQKAVAEVMAERLFDSIVSRMVKEFR 286
Query: 313 PRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFY 372
RRD + L + KPEG +++V + D + E + GVA PG F
Sbjct: 287 QRRDYLYSELSKIYDV----VKPEGAFYMFVNVNQ--DCMEYAENLINLGVAVTPGLPF- 339
Query: 373 AYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
N + +Y + E +K+ AE I+E
Sbjct: 340 ---GDGNETYVRISYANS---LENLKKAAEIIRE 367
>emb|CAB61674.1| (AL133213) putative GntR-family regulatory protein. [Streptomyces
coelicolor A3(2)]
Length = 500
Score = 107 bits (265), Expect = 2e-22
Identities = 83/311 (26%), Positives = 140/311 (44%), Gaps = 12/311 (3%)
Query: 81 GFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAAL 140
G LR + + R + IM+T+G+ A+D I +F G+ + VE+P+Y L
Sbjct: 160 GLPALRAMIAERYTARGIPTMPEQIMVTTGAMGAIDAICHLFGGRGERIAVESPSYANIL 219
Query: 141 QAFNFYEPKYIQVPLDDN--GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSE 198
Q + + V + + G +V+ LR +I Y V F NP G +
Sbjct: 220 QLMREAGARLVPVAMAEGLTGWDVDRWRQVLRDAAP-----RIAYVVADFHNPTGALADD 274
Query: 199 ERRKHLIELASEYDLIVIEDDPYGELRYSGKPK--KKIKALDKEGR-VIYLGTFSKILAP 255
++R+ L++ A +++ D+ EL + + + A D G VI +G+ SK
Sbjct: 275 DQRRRLVDAARSAGTVLVADETMSELWLDEDVEMPRPVCAFDPAGSTVITVGSASKAFWA 334
Query: 256 GFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRR 315
G RIGW+ P +IR L A+ DL T V Q+ S G ++ + RE + R
Sbjct: 335 GMRIGWVRAAPDVIRSLVAARAYADLGTPVLEQLAVNWLFSTGGWEQAVTVRREQARQNR 394
Query: 316 DAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYR 375
D ++ A+ +P+ ++ P GG+ +WV G+ ++ E + GV G F
Sbjct: 395 DELVAAVRRELPD-WEFEVPRGGLTLWVR-TGGLSGSRLAEAGERVGVRVPSGPRFGVDG 452
Query: 376 DVKNTMRLNFT 386
+ +RL FT
Sbjct: 453 AFEGYVRLPFT 463
>pir||F83024 aspartate transaminase PA4976 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9951259|gb|AAG08361.1|AE004910_8
(AE004910) aspartate transaminase [Pseudomonas
aeruginosa]
Length = 393
Score = 106 bits (263), Expect = 4e-22
Identities = 99/389 (25%), Positives = 187/389 (47%), Gaps = 28/389 (7%)
Query: 29 RELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRET 88
R L ++ + +I+ L+ G P+ T P I++ + ++ + Y +G LR+
Sbjct: 23 RALARVEQGEEILLLSVGDPDFDT-PAPIVQAAIDSLLAGNT----HYADVRGKRALRQR 77
Query: 89 LLDWLEKRYGISKEND-IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYE 147
+ + +R G + + + +++ +G+Q AL + + ++PGD VIV P Y+ F
Sbjct: 78 IAERHRRRSGQAVDAEQVVVLAGAQCALYAVVQCLLNPGDEVIVAEPMYVTYEAVFGACG 137
Query: 148 PKYIQVPL-DDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIE 206
+ + VP+ +NG V+A +E+ L + + + NP+G ++ + L E
Sbjct: 138 ARVVPVPVRSENGFRVQA--EEVAALITPRTRAMALNSP---HNPSGASLPRATWEALAE 192
Query: 207 LASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA-PGFRIGWIVGD 265
L +DL +I D+ Y EL + G+ R L + SK A G+R+GW+VG
Sbjct: 193 LCMAHDLWMISDEVYSELLFDGEHVSPASLPGMADRTATLNSLSKSHAMTGWRVGWVVGP 252
Query: 266 PGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKI---REFYKPRRDAMLEAL 322
+ LE + LC ++G + + L+ +P++ RE Y+ RRD ++E L
Sbjct: 253 AALCAHLE----NLALCM-LYGSPEFIQDAACTALEAPLPELEAMREAYRRRRDLVIECL 307
Query: 323 EEFMPENVKWTKPEGGMFVWVTL-PDGIDSKKMLEKAV-KKGVAYVPGEAFYAYRDVKNT 380
+ ++ +P+GGMFV V + P G+ ++ ++ + + GV+ + GEAF
Sbjct: 308 AD--SPGLRPLRPDGGMFVMVDIRPTGLSAQAFADRLLDRHGVSVLAGEAFGP--SAAGH 363
Query: 381 MRLNFTYVDEDKIREGVKRLAETIKEETG 409
+RL + + +RE +R+A E G
Sbjct: 364 IRLGLV-LGAEPLREACRRIALCAAELLG 391
>pir||D70479 probable transaminase (EC 2.6.1.-) aspC2 [similarity] - Aquifex
aeolicus >gi|2984300|gb|AAC07823.1| (AE000772)
aminotransferase (AspC family) [Aquifex aeolicus]
Length = 414
Score = 106 bits (261), Expect = 6e-22
Identities = 99/390 (25%), Positives = 177/390 (45%), Gaps = 41/390 (10%)
Query: 36 ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEK 95
E D++ L G+ NP P + I + L E+ ++ Y ++G LR+ + ++ E+
Sbjct: 34 EGEDVVDL--GMGNPNMPPAKHIIDKLCEVAQK--PNVHGYSASRGIPRLRKAICNFYEE 89
Query: 96 RYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEP----- 148
RYG+ E + ++T G+++ + I PGD VIV PTY ++Y P
Sbjct: 90 RYGVKLDPEREAILTIGAKEGYSHLMLAMISPGDTVIVPNPTY-----PIHYYAPIIAGG 144
Query: 149 KYIQVPL---DDNGMNVEALEDELRKLKAEGKKVK-IVYTVPTFQNPAGVTMSEERRKHL 204
+ +PL DD E L +K K K +V + P NP +T+ ++ K +
Sbjct: 145 EVHSIPLNFSDDQDHQEEFLRRLYEIVKTAMPKPKAVVISFP--HNPTTITVEKDFFKEI 202
Query: 205 IELASEYDLIVIEDDPYGELRYSG-KPKKKIKALDKEGRVIYLGTFSK-ILAPGFRIGWI 262
++ A E+ L +I D Y ++ + G KP ++ + + L + SK G+R+ ++
Sbjct: 203 VKFAKEHGLWIIHDFAYADIAFDGYKPPSILEIEGAKDVAVELYSMSKGFSMAGWRVAFV 262
Query: 263 VGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEAL 322
VG+ +I+ L K D +F + ++ + K + Y+ RRD ++E L
Sbjct: 263 VGNEILIKNLAHLKSYLDY--GIFTPIQVASIIALESPYEIVEKTAKVYQKRRDVLVEGL 320
Query: 323 EEFMPENVKWTKPEGGMFVWVTLPD-----GIDSKKMLEKAVKKGVAYVPGEAFYAYRDV 377
K KP+ MFVW +P+ +D L K K VA PG F Y +
Sbjct: 321 NRL---GWKVKKPKATMFVWAKIPEWINMNSLDFSLFLLKEAK--VAVSPGVGFGQYGE- 374
Query: 378 KNTMRLNFTYVD-EDKIREGVKRLAETIKE 406
+ F V+ E +IR+ ++ + + ++
Sbjct: 375 ---GYVRFALVENEHRIRQAIRGIRKAFRK 401
>sp|Q56232|AAT_THETH ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|2120597|pir||JC4537 aspartate transaminase (EC
2.6.1.1) [validated] - Thermus aquaticus (strain HB8)
>gi|5821839|pdb|1BKG|A Chain A, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|5821840|pdb|1BKG|B Chain B, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|5821841|pdb|1BKG|C Chain C, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|5821842|pdb|1BKG|D Chain D, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|1255699|dbj|BAA07487.1| (D38459) aspartate
aminotransferase [Thermus thermophilus]
>gi|1587013|prf||2205299A Asp aminotransferase [Thermus
aquaticus thermophilus]
Length = 385
Score = 105 bits (259), Expect = 1e-21
Identities = 103/394 (26%), Positives = 176/394 (44%), Gaps = 38/394 (9%)
Query: 20 AMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTT 79
A+ KA E+R + D+++L G P+ T E ++E A +AL G T
Sbjct: 18 AVNAKALELRR-----QGVDLVALTAGEPDFDT----------PEHVKEAARRALAQGKT 62
Query: 80 K-----GFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEA 133
K G LRE L + + G+S + ++T G +QAL + + +DPGD VIV +
Sbjct: 63 KYAPPAGIPELREALAEKFRRENGLSVTPEETIVTVGGKQALFNLFQAILDPGDEVIVLS 122
Query: 134 PTYLAALQAFNFYEPKYIQVP-LDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPA 192
P +++ + F ++V L + G + D R +A + K + V + NP
Sbjct: 123 PYWVSYPEMVRFAGGVVVEVETLPEEGF----VPDPERVRRAITPRTKAL-VVNSPNNPT 177
Query: 193 GVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKI 252
G +E + L LA E+D ++ D+ Y L Y G+ + + E + G
Sbjct: 178 GAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSPGR-VAPEHTLTVNGAAKAF 236
Query: 253 LAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDR-HIPKIREFY 311
G+RIG+ G +I+ + + + Q + ++ R + RE Y
Sbjct: 237 AMTGWRIGYACGPKEVIKAMASVSSQSTTSPDTIAQWATLEALTNQEASRAFVEMAREAY 296
Query: 312 KPRRDAMLEALEEFMPENVKWTKPEGGMFVWV-TLPDGIDSKKMLEKAVKKGVAYVPGEA 370
+ RRD +LE L +K +P G +V + T P D + E+ ++ GVA VPG
Sbjct: 297 RRRRDLLLEGLTAL---GLKAVRPSGAFYVLMDTSPIAPDEVRAAERLLEAGVAVVPGTD 353
Query: 371 FYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETI 404
F A+ V RL++ E+ +R+ ++R A +
Sbjct: 354 FAAFGHV----RLSYA-TSEENLRKALERFARVL 382
>pdb|1BJW|A Chain A, Aspartate Aminotransferase From Thermus Thermophilus
>gi|5821837|pdb|1BJW|B Chain B, Aspartate
Aminotransferase From Thermus Thermophilus
Length = 382
Score = 105 bits (259), Expect = 1e-21
Identities = 103/394 (26%), Positives = 176/394 (44%), Gaps = 38/394 (9%)
Query: 20 AMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTT 79
A+ KA E+R + D+++L G P+ T E ++E A +AL G T
Sbjct: 18 AVNAKALELRR-----QGVDLVALTAGEPDFDT----------PEHVKEAARRALAQGKT 62
Query: 80 K-----GFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEA 133
K G LRE L + + G+S + ++T G +QAL + + +DPGD VIV +
Sbjct: 63 KYAPPAGIPELREALAEKFRRENGLSVTPEETIVTVGGKQALFNLFQAILDPGDEVIVLS 122
Query: 134 PTYLAALQAFNFYEPKYIQVP-LDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPA 192
P +++ + F ++V L + G + D R +A + K + V + NP
Sbjct: 123 PYWVSYPEMVRFAGGVVVEVETLPEEGF----VPDPERVRRAITPRTKAL-VVNSPNNPT 177
Query: 193 GVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKI 252
G +E + L LA E+D ++ D+ Y L Y G+ + + E + G
Sbjct: 178 GAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSPGR-VAPEHTLTVNGAAXAF 236
Query: 253 LAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDR-HIPKIREFY 311
G+RIG+ G +I+ + + + Q + ++ R + RE Y
Sbjct: 237 AMTGWRIGYACGPKEVIKAMASVSSQSTTSPDTIAQWATLEALTNQEASRAFVEMAREAY 296
Query: 312 KPRRDAMLEALEEFMPENVKWTKPEGGMFVWV-TLPDGIDSKKMLEKAVKKGVAYVPGEA 370
+ RRD +LE L +K +P G +V + T P D + E+ ++ GVA VPG
Sbjct: 297 RRRRDLLLEGLTAL---GLKAVRPSGAFYVLMDTSPIAPDEVRAAERLLEAGVAVVPGTD 353
Query: 371 FYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETI 404
F A+ V RL++ E+ +R+ ++R A +
Sbjct: 354 FAAFGHV----RLSYA-TSEENLRKALERFARVL 382
>pir||G69119 probable aspartate transaminase (EC 2.6.1.1) MTH1894 [similarity] -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2623027|gb|AAB86354.1| (AE000941) aspartate
aminotransferase homolog [Methanobacterium
thermoautotrophicum]
Length = 374
Score = 103 bits (255), Expect = 3e-21
Identities = 97/393 (24%), Positives = 185/393 (46%), Gaps = 30/393 (7%)
Query: 12 VERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHAD 71
+ R F+ + +++ SE+R++ ++ + D I+L G P+ + + + E +++ D
Sbjct: 2 IMRKFASRVKDIQLSEIRKIFEVAD-EDTINLGIGEPDFS------VPDHVREAVKDAVD 54
Query: 72 KAL-QYGTTKGFTPLRETLLDWLEKRYGISKEND-IMITSGSQQALDLIGRVFIDPGDIV 129
+ L Y + G LRE + D L+ + E + I++T G+ +A+ + + +D GD
Sbjct: 55 EGLTHYTSNMGMEELREAIADKLKSENRVHAEPESIIVTVGASEAIFMCTQALLDIGDHA 114
Query: 130 IVEAPTYLAALQAFNFYEPKYIQVPLD-DNGMNVEALEDELRKLKAEGKKVKIVYTVPTF 188
++ P +L+ I VPL D G ++ + + L + +V I+ P+
Sbjct: 115 LIPDPGFLSYDACVRLSGAVSIPVPLSMDEGFSMSP--ERVESLITQDTRV-IIMNSPS- 170
Query: 189 QNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGT 248
NP G M ++ K + E+A + DLI+I D+ Y ++ Y GK + D + +
Sbjct: 171 -NPTGSVMGKDDVKGIAEIAEDNDLIIISDEIYEKIIYDGKHYSPAQFTD---NALIVNG 226
Query: 249 FSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKI 307
FSK A G RIG++ G II +L Q C Q A + + +
Sbjct: 227 FSKTYAMTGLRIGYVAGCEDIIEELLKVHQYNTACAPSISQYAALAAIRGP--QNCVKDM 284
Query: 308 REFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVP 367
+ ++ RRD M +L + ++ P G +++ P DS++ + +++ GVA VP
Sbjct: 285 VDEFRRRRDLMFRSLTDM---GLECVLPGGAFYMF---PYAGDSEEFTKLSLEAGVAVVP 338
Query: 368 GEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
G AF + K +R+++ + I E ++RL
Sbjct: 339 GSAF--GNEGKGYIRMSYA-TSYELIEEAMERL 368
>pir||B70325 probable transaminase (EC 2.6.1.-) aspC4 [similarity] - Aquifex
aeolicus >gi|2982964|gb|AAC06578.1| (AE000681)
aminotransferase (AspC family) [Aquifex aeolicus]
Length = 387
Score = 103 bits (255), Expect = 3e-21
Identities = 93/376 (24%), Positives = 174/376 (45%), Gaps = 27/376 (7%)
Query: 33 KLVETSDIISLAGGLPNPKTFPKEIIKEI--LIEIMEEHADKALQYGTTKGFTPLRETLL 90
K+ + D+I L G P+ T PK I++ +E E H +Y + G R+ +
Sbjct: 26 KIEQGVDVIDLGVGDPDMPT-PKPIVEAAKKALENPENH-----KYPSYVGKYEFRKAVA 79
Query: 91 DWLEKRYGISKE--NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEP 148
DW ++R+ + + +++ GS++ + F++PGDIV+ P Y F
Sbjct: 80 DWYKRRFDVDLDPNTEVITLIGSKEGIAHFPLAFVNPGDIVLCPDPAYPVYRIGAIFAGG 139
Query: 149 KYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELA 208
VPL + + L+ + + K + I Y NP + E K L++ A
Sbjct: 140 TPYTVPLKEENNFLPDLDSIPEDVAKKAKIIWINYP----NNPTSAPPTLEFYKKLVDWA 195
Query: 209 SEYDLIVIEDDPYGELRYSG--KPKKKIKALDKEGRVIYLGTFSKIL-APGFRIGWIVGD 265
EY++I+ D+ Y E+ Y+G KP ++ + I + SK G+RIG VG+
Sbjct: 196 KEYNVIIASDNAYSEI-YTGQEKPPSILQVPGAKDVAIEFHSLSKTYNMTGWRIGMAVGN 254
Query: 266 PGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEF 325
++ L K T++ + FG V V+ + + KIR+ Y+ R+ M EALE+
Sbjct: 255 KELVAGL--GKVKTNVDSGQFGAVQDAGIVALNLPEEEVEKIRDVYRERKKIMTEALEKI 312
Query: 326 MPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAV-KKGVAYVPGEAFYAYRDVKNTMRLN 384
++ + + ++W+ +P+G S + + + + + G+ PG F Y + R++
Sbjct: 313 ---GLEIYRSDYTFYLWIKVPEGYTSAEFVGRLIDEAGIVCTPGNGFGEYGE--GYFRIS 367
Query: 385 FTYVDEDKIREGVKRL 400
T V +++ E +R+
Sbjct: 368 LT-VPTERLLEAAERI 382
>gb|AAB81842.1| (AF025665) aspartate aminotransferase [Thermus aquaticus]
Length = 383
Score = 103 bits (254), Expect = 4e-21
Identities = 105/414 (25%), Positives = 184/414 (44%), Gaps = 43/414 (10%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
+ + +KSM + + +A+E++ V D+++L G P+ T P +
Sbjct: 4 LSQRVKSMKPSATVVVNARALELRRKGV----------DLVALTAGEPDFDT-PHHV--- 49
Query: 61 ILIEIMEEHADKALQYGTTK-----GFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQA 114
+E A + L G TK G LRE + + G+ + ++T G +QA
Sbjct: 50 ------KERARRGLAQGKTKYAPPAGIPELREAVAEKFRGENGLEVTPEETIVTVGGKQA 103
Query: 115 LDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP-LDDNGMNVEALEDELRKLK 173
L + + +DPGD VIV AP +++ + F ++VP L + G + D R +
Sbjct: 104 LFNLFQAILDPGDEVIVLAPYWVSYPEMVRFAGGVPVEVPTLPEEGF----VPDPERVRR 159
Query: 174 AEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKK 233
A + K + V + NP GV EE + L E+A ++D ++ D+ Y L Y G
Sbjct: 160 AITPRTKAL-VVNSPNNPTGVVYPEEVCEALAEMALQHDFYLVSDEIYEHLIYEGAHFSP 218
Query: 234 IKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKL-EIAKQSTDLCTNVFGQVVAW 292
+ L E + + G+RIG+ G +I+ + +++ QST +
Sbjct: 219 -RHLAPEHTITVERAANAFAMTGWRIGYACGPKAVIKAMADVSSQSTTSPDTIAQWATLE 277
Query: 293 KYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWV-TLPDGIDS 351
+ I RE Y+ RRD +LE L E V +P G +V + T P +
Sbjct: 278 ALTNREASMAFIAMAREAYRKRRDLLLEGLSRIGLEAV---RPSGAFYVLMDTSPFAPNE 334
Query: 352 KKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIK 405
+ E+ + GVA VPG F A+ V RL++ E+ +++ ++R A+ ++
Sbjct: 335 VEAAERLLMAGVAVVPGTDFAAFGHV----RLSYA-TGEENLKKALERFAQALQ 383
>gi|6321000 Yer152cp [Saccharomyces cerevisiae] >gi|731527|sp|P10356|YEY2_YEAST
HYPOTHETICAL 49.5 KD PROTEIN IN UBP3-PET122 INTERGENIC
REGION >gi|1071786|pir||QQBYPT hypothetical protein
YER152c - yeast (Saccharomyces cerevisiae)
>gi|603392|gb|AAB64679.1| (U18917) Yer152cp
[Saccharomyces cerevisiae]
Length = 443
Score = 101 bits (250), Expect = 1e-20
Identities = 70/252 (27%), Positives = 116/252 (45%), Gaps = 32/252 (12%)
Query: 181 IVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYS------GKPKKKI 234
++Y +PTF NP+G T S E R+ LI++A +YD+++I DD Y L Y+ P ++
Sbjct: 187 VMYCIPTFANPSGNTYSLETRRRLIDIARKYDMLIITDDVYDILDYTTPSDELPSPPLRM 246
Query: 235 KALDKE---------GRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNV 285
+D+ G + TFSK++APG R G+ +A+Q + NV
Sbjct: 247 VHIDRSTAPSGEDSFGNTVSNATFSKLIAPGLRFGYHES-----INANLARQLSKGGANV 301
Query: 286 FG-------QVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGG 338
G ++ + + G R I +R Y R + AL+++MP + +GG
Sbjct: 302 SGGTPSQLNSMIVGEMLRSGAAQRCIAHLRSVYSERATVLTSALKKYMPLGTEIMPLKGG 361
Query: 339 MFVWVTLPDGIDSKKMLEKAVKK-GVAYVPGEAFYAYRDVKN----TMRLNFTYVDEDKI 393
F W+TLP ++ ++ KK V G F D KN RL+ ++++ D I
Sbjct: 362 YFTWITLPPAYNAMEISTILAKKFNVILADGSNFEVIGDEKNWGQSCFRLSISFLEVDDI 421
Query: 394 REGVKRLAETIK 405
G++ K
Sbjct: 422 DRGIELFGAVCK 433
>pir||D71003 probable transaminase (EC 2.6.1.-) PH1322 [similarity] - Pyrococcus
horikoshii >gi|3257745|dbj|BAA30428.1| (AP000006) 401aa
long hypothetical aspartate aminotransferase [Pyrococcus
horikoshii]
Length = 401
Score = 101 bits (250), Expect = 1e-20
Identities = 90/336 (26%), Positives = 161/336 (47%), Gaps = 32/336 (9%)
Query: 54 PKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQ 112
P E +KE ++E + YG ++G LRE ++ +++ G+ +D+ +T+
Sbjct: 50 PPEHMKEAYCRAIQEGHN---YYGDSEGLIELREAIVKREKEKNGVDITPDDVRVTAAVT 106
Query: 113 QALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQV-PLDDNGMNVEALEDELRK 171
+AL LI +DPGD +++ P+Y FY K ++ +++ G + D+LRK
Sbjct: 107 EALQLIFGALLDPGDEILIPGPSYPPYTGLVKFYGGKPVEYRTIEEEGWQPDI--DDLRK 164
Query: 172 LKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPK 231
+E K V NP G ++ + +I +A E+DL+V+ D+ Y + Y GK
Sbjct: 165 KISERTKAIAVINP---NNPTGALYDKKTIEEIINVAGEHDLVVLSDEIYDLMTYEGKHI 221
Query: 232 KKIKALDKEGRVIYLGTFSKI-LAPGFRIGWI-VGDPGIIRKLEIAKQSTD------LCT 283
+L K+ VI + SK+ A G+R+G++ DP KL +++ D +C
Sbjct: 222 SP-GSLTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPE--GKLSEVREAIDKLARIRICP 278
Query: 284 NVFGQ--VVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFV 341
N GQ +A S +L ++ K++E RRD + + L E + TKP+G ++
Sbjct: 279 NTPGQFAAIAGLTGSMDYLKEYMKKLKE----RRDFIYKRLNEI--PGISTTKPQGAFYI 332
Query: 342 WVTLPDG---IDSKKMLEKAVKKGVAYVPGEAFYAY 374
+ + +G D + +L+ V +V G F Y
Sbjct: 333 FPRIEEGPWKSDKEFVLDVLHNAHVLFVHGSGFGEY 368
>gb|AAD24445.1|AF118389_2 (AF118389) unknown [Streptococcus suis]
Length = 419
Score = 101 bits (248), Expect = 2e-20
Identities = 81/329 (24%), Positives = 153/329 (45%), Gaps = 22/329 (6%)
Query: 76 YGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDI-VIVEAP 134
Y +G L ++ L + +K++ ++IT+GSQQAL ++ ++ G +++E P
Sbjct: 111 YHQQEGLAELISSVQSLLMDYHVYTKKDQLVITAGSQQALYILTQMETLAGKTEILIENP 170
Query: 135 TYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGV 194
TY ++ Y + + +G+++E LE + K+K YT+P NP G
Sbjct: 171 TYSRMIELIRHQGIPYQTIERNLDGIDLEELESIFQT-----GKIKFFYTIPRLHNPLGS 225
Query: 195 TMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA 254
T + +++LA +YD+ +IEDD + + + LD + RVIY+ +F+ L
Sbjct: 226 TYDIATKTAIVKLAKQYDVYIIEDDYLAD--FDSSHSLPLHYLDTDNRVIYIKSFTPTLF 283
Query: 255 PGFRIGWIVGDPGIIRKLEIAKQS-TDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKP 313
P RIG + P +R + I +S D TN+ Q Y+ G R+ + Y
Sbjct: 284 PALRIG-AISLPNQLRDIFIKHKSLIDYDTNLIMQKALSLYIDNGMFARNTQHLHHIYHA 342
Query: 314 RRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYA 373
+ + + + LE++ N+ + P+G V L GI + + ++ G+ +Y
Sbjct: 343 QWNKIKDCLEKY-ALNIPYRIPKGS--VTFQLSKGI---------LSPSIQHMFGKCYYF 390
Query: 374 YRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
+ +++ F DK+ + V+ L E
Sbjct: 391 SGQKADFLQIFFEQDFADKLEQFVRYLNE 419
>sp|Q01856|YRDX_RHOSH HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN RDXA 3'REGION
>gi|538855|pir||B45728 rdxA 3'-region protein -
Rhodobacter sphaeroides >gi|151928|gb|AAA26118.1|
(M94725) 48 kDa protein [Rhodobacter sphaeroides]
Length = 456
Score = 100 bits (246), Expect = 4e-20
Identities = 81/336 (24%), Positives = 151/336 (44%), Gaps = 25/336 (7%)
Query: 73 ALQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVE 132
A+ Y + G R WL R + + I++TSG+Q AL + + + GD+V
Sbjct: 125 AMHYQESTGAPADRTAAASWLAGRVAGASADRIVVTSGAQAALFALCALLLGRGDVVAAG 184
Query: 133 APTY--LAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQN 190
A TY L A+ A E V +D+ G+ EA E R+ + K++Y +P+ N
Sbjct: 185 AVTYPGLKAVAAQQHLE--LAPVAMDEQGILPEAFEAVCRE-----RAPKLLYLIPSIDN 237
Query: 191 PAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVI--YLGT 248
P T+ +RR+ + +A + +++IEDDPY LR +++ AL + + ++ T
Sbjct: 238 PTTATLPADRRREVAAVARRHGVLLIEDDPYAPLR-----SERLPALAELAPELTWHIAT 292
Query: 249 FSKILAPGFRIGWIVGD--PGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK 306
SK P RI +++ +R + + S + +F +A +++++G L
Sbjct: 293 LSKCSTPALRIAYVLAPNAAAAVRLATVLRSSVLMAPPIFA-ALATRWITDGTLTALASA 351
Query: 307 IREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYV 366
IR + R+ + + + G +W+ LP + + + A + G+A V
Sbjct: 352 IRAENRQRQSSAASIF-----SGLDFAADPDGHHLWLHLPQRWRAAEFADHAERAGLAIV 406
Query: 367 PGEAFYAYRDVKNTMRLNFTYV-DEDKIREGVKRLA 401
P AF +R++ D + EG+ +L+
Sbjct: 407 PASAFAVSPHPAEAVRISLGIAPDRGMLEEGLTQLS 442
>sp|P53001|AAT1_BACSU ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447803|pir||C69591 aspartate transaminase (EC
2.6.1.1) aspB [similarity] - Bacillus subtilis
>gi|1146246|gb|AAB38454.1| (L47709) aspartate
aminotransferase [Bacillus subtilis]
>gi|2634655|emb|CAB14153.1| (Z99115) aspartate
aminotransferase [Bacillus subtilis]
Length = 393
Score = 99.1 bits (243), Expect = 8e-20
Identities = 104/420 (24%), Positives = 189/420 (44%), Gaps = 50/420 (11%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
+ + + ++ + + KA E+KA+ D+I L G P+ T P+ II
Sbjct: 3 LAKRVSALTPSTTLAITAKAKELKAAG----------HDVIGLGAGEPDFNT-PQHIIDA 51
Query: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIG 119
+ + E H +Y + G L+ ++ + ++ I K + I++ +G++ AL +
Sbjct: 52 AVRSMNEGHT----KYTPSGGLAELKNSIAEKFKRDQNIEYKPSQIIVCTGAKHALYTLF 107
Query: 120 RVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP-LDDNGMNVEALEDELRKLKAEGKK 178
+V +D D VI+ P +++ + K + V L++N + ++L+ E K
Sbjct: 108 QVILDEEDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEENHFKISP--EQLKNAITEKTK 165
Query: 179 VKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALD 238
IV P+ NP GV +EE L E+ E+D++++ D+ Y +L Y GK I L
Sbjct: 166 A-IVINSPS--NPTGVMYTEEELSALGEVCLEHDILIVSDEIYEKLTYGGKKHVSIAQLS 222
Query: 239 ---KEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKL-EIAKQSTDLCTNV--FGQVVAW 292
KE VI G G+RIG+ G II+ + +A ST T++ +G + A+
Sbjct: 223 DRLKEQTVIINGVSKSHSMTGWRIGYAAGSEDIIKAMTNLASHSTSNPTSIAQYGAIAAY 282
Query: 293 KYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDS- 351
SE + ++RE ++ R + + L E KPEG +++ + S
Sbjct: 283 NGPSE-----PLEEMREAFEHRLNTIYAKLIEI--PGFSCVKPEGAFYLFPNAKEAAQSC 335
Query: 352 ---------KKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
K +LE ++ VA VPG F + +V+ + + ++E E +KR E
Sbjct: 336 GFKDVDEFVKALLE---EEKVAIVPGSGFGSPENVRLSYATSLDLLEE--AIERIKRFVE 390
>gb|AAK41425.1| Aspartate aminotransferase (aspB-3) [Sulfolobus solfataricus]
Length = 356
Score = 98.3 bits (241), Expect = 1e-19
Identities = 84/306 (27%), Positives = 143/306 (46%), Gaps = 32/306 (10%)
Query: 74 LQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEA 133
L+YG TKG LR+ + + Y KE D++IT+G +A + I+PGD VIVE
Sbjct: 42 LEYGHTKGLIKLRQLVSSF----YPGKKEEDVIITAGGAEANYVTVLSTIEPGDEVIVEM 97
Query: 134 PTYLAALQAFNFYEPKYIQVPLDDN-GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPA 192
P Y+ K + L+DN +++ L + + K K IV T P NP
Sbjct: 98 PNYMQIPGLLRGINAKIKYIWLNDNFKLDLNELNEMVSK-----KTKAIVITNP--NNPT 150
Query: 193 GVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKI 252
G+ +SE K ++++A + + +I D+ Y + G + +D I + SK+
Sbjct: 151 GMALSESEIKGIVDIAEDNQVTIIADEVYRGSEHDGNIRPSF--IDLYDNAISTNSMSKV 208
Query: 253 LA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFY 311
PG RIGW+V + ++ K+ + T + ++ GQ +A+ + E K +
Sbjct: 209 YGLPGIRIGWVVANKELVDKMWSIRDYTSISPSILGQEIAYNVLLE--------KEKYMD 260
Query: 312 KPRRDAM--LEALEEFMPE-NVKWTKPEGGMFVWVTL--PDGID-SKKMLEKAVKKGVAY 365
+ RR + + LE + + +VKW +P + ++ L + D S ++ E K V
Sbjct: 261 RARRIGLNNIRLLERLISDIDVKWVEPNATVLAYLKLNVKNTYDFSARLFE---KYSVLV 317
Query: 366 VPGEAF 371
PGE F
Sbjct: 318 NPGECF 323
>sp|O67781|AAT_AQUAE ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447804|pir||A70469 aspartate transaminase (EC
2.6.1.1) aspC1 [similarity] - Aquifex aeolicus
>gi|2984217|gb|AAC07746.1| (AE000766) aspartate
aminotransferase [Aquifex aeolicus]
Length = 394
Score = 98.3 bits (241), Expect = 1e-19
Identities = 109/405 (26%), Positives = 184/405 (44%), Gaps = 51/405 (12%)
Query: 19 KAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGT 78
KA E++A V D+I G P+ T + IKE I + E K Y
Sbjct: 23 KAKELRAKGV----------DVIGFGAGEPDFDT--PDFIKEACIRALREGKTK---YAP 67
Query: 79 TKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYL 137
+ G LRE + + L K + K ++I++++G++ L LI +D GD V++ +P ++
Sbjct: 68 SAGIPELREAIAEKLLKENKVEYKPSEIVVSAGAKMVLFLIFMAILDEGDEVLLPSPYWV 127
Query: 138 AALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMS 197
+ F+ ++VPL +LED K+ K + + + NP G
Sbjct: 128 TYPEQIRFFGGVPVEVPLKKEKGFQLSLEDVKEKVTERTKAI----VINSPNNPTGAVYE 183
Query: 198 EERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVI--YLGTFSKILA- 254
EE K + E E + +I D+ Y Y + E + I + FSK +
Sbjct: 184 EEELKKIAEFCVERGIFIISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKSYSM 243
Query: 255 PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNV--FGQVVAWKYVSEGHLDRHIPKIREFYK 312
G+RIG+ V P K+ IA ++ +NV F Q A + + + ++R ++
Sbjct: 244 TGWRIGY-VACPEEYAKV-IASLNSQSVSNVTTFAQYGALEALKNPKSKDFVNEMRNAFE 301
Query: 313 PRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD--------GID---SKKMLEKAVKK 361
RRD +E L + +V KPEG +++ PD G D S+ +LEKA
Sbjct: 302 RRRDTAVEELSKIPGMDV--VKPEGAFYIF---PDFSAYAEKLGGDVKLSEFLLEKA--- 353
Query: 362 GVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
VA VPG AF A +RL++ + E+++ EG++R+ + ++E
Sbjct: 354 KVAVVPGSAFGA----PGFLRLSYA-LSEERLVEGIRRIKKALEE 393
>emb|CAC11669.1| (AL445064) probable aspartate aminotransferase [Thermoplasma
acidophilum]
Length = 377
Score = 98.3 bits (241), Expect = 1e-19
Identities = 90/332 (27%), Positives = 156/332 (46%), Gaps = 21/332 (6%)
Query: 76 YGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPT 135
Y + G LRE + L+ R I + ++ + ++ ++L V ++PGD VI+ P
Sbjct: 57 YTPSAGIMELREKIASKLKTRNRIDANAENVLVTPTKFGINLAMMVILNPGDEVIIPDPY 116
Query: 136 YLAALQAFNFYEPKYIQV-PLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGV 194
Y++ K + V DD +++ DE+RK + I+ P NP G
Sbjct: 117 YVSYPDIVKLAGGKPVPVRTTDDYDIDL----DEMRKFVTPRTRA-IILNNPN--NPTGK 169
Query: 195 TMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEG--RVIYLGTFSKI 252
+SE+ + L++ A E D+ ++ D+ Y +L Y G ++ KE I L FSK
Sbjct: 170 VLSEKEIRDLVDFALENDIYIVSDEIYEDLIYEGSLYSP-ASMGKEAFEHTITLNGFSKG 228
Query: 253 LA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFY 311
A G+RIG+ V I+ I +Q T C + Q A + + + + ++R +
Sbjct: 229 YAMTGWRIGYFVATEEIVEAANIIQQQTITCASSISQYAALRALDD---NESPARMRSEF 285
Query: 312 KPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAV-KKGVAYVPGEA 370
+ RRD L E ++K KPEG +++ I S+K+ E + ++ V PG A
Sbjct: 286 RKRRDLAYGILSE--STDMKVHKPEGAFYMFPGYSKDIPSEKIAEMLLNQEHVVVTPGSA 343
Query: 371 FYAYRDVKNTMRLNFTYVDEDKIREGVKRLAE 402
F ++ R++F ED I+EG++RL +
Sbjct: 344 FGDRG--RHHFRISFA-TSEDIIKEGLERLVK 372
>pir||B69764 transcription regulator GntR family homolog ycnF - Bacillus
subtilis >gi|1805458|dbj|BAA09020.1| (D50453) homologue
of regulatory protein MocR of R. meliloti [Bacillus
subtilis] >gi|2632690|emb|CAB12197.1| (Z99106) similar
to transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
Length = 479
Score = 97.9 bits (240), Expect = 2e-19
Identities = 77/330 (23%), Positives = 140/330 (42%), Gaps = 15/330 (4%)
Query: 80 KGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAA 139
+G +R + + G+ + MI Q L + + + +E P Y
Sbjct: 149 QGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPGYRRM 208
Query: 140 LQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEE 199
Q + + LD+ GM++ + + + ++ T P+ Q P+G M
Sbjct: 209 YQLLKNAGKQVKTIMLDEKGMSIAEITRQ---------QPDVLVTTPSHQFPSGTIMPVS 259
Query: 200 RRKHLIELASEYDL-IVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFR 258
RR L+ A+E +IEDD E Y +++LD+ VIY+GTFSK L PG R
Sbjct: 260 RRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTFSKSLLPGLR 319
Query: 259 IGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAM 318
I ++V P ++R + C+++ Q+ +++ G +HI K+++ YK +R+ +
Sbjct: 320 ISYMVLPPELLRAYKQRGYDLQTCSSL-TQLTLQEFIESGEYQKHIKKMKQHYKEKRERL 378
Query: 319 LEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVK 378
+ ALE V G+ + +L A + F + +
Sbjct: 379 ITALEAEFSGEVTVKGANAGLHFVTEFDTRRTEQDILSHAAGLQLEIFGMSRFNLKENKR 438
Query: 379 NTMR----LNFTYVDEDKIREGVKRLAETI 404
T R + F + E+ I+EGV+RL + +
Sbjct: 439 QTGRPALIIGFARLKEEDIQEGVQRLFKAV 468
>dbj|BAB04655.1| (AP001510) aspartate aminotransferase [Bacillus halodurans]
Length = 385
Score = 97.9 bits (240), Expect = 2e-19
Identities = 84/356 (23%), Positives = 160/356 (44%), Gaps = 28/356 (7%)
Query: 60 EILIEIMEEHADKALQYG-TTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDL 117
+ +++ M + QYG G E + + ++RY ++ K + ++ GSQ L
Sbjct: 47 DFVVQKMNAYVSNPNQYGYAITGLAAFHEAVAQFYQRRYQVNVKPHQVLSLMGSQDGLAH 106
Query: 118 IGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGM---NVEALEDELRKLKA 174
+ ++D GD+++ P Y + + + PL++ +VE L D++++
Sbjct: 107 LALAYVDAGDLLLAPDPGYPIYAASAHIAGAELYTYPLNEENQFMFDVETLPDDVKQ--- 163
Query: 175 EGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKI 234
K ++ P NP E + L+ E++++++ D Y EL + + I
Sbjct: 164 --KAKLMIVNYPG--NPTAAMADEAYFEKLVAFGIEHNILIVHDYAYSELLFDQREALSI 219
Query: 235 KALDK--EGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAW 292
++ + E + + G RIG+ +G I++ L K D VF V
Sbjct: 220 FSVPRAFETAIEFNSLSKSFNIAGARIGYAIGAESILQPLAALKSHLDY--GVFLPVQYG 277
Query: 293 KYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWT--KPEGGMFVWVTLP-DGI 349
+ H D + RE Y+ RR+ +EAL+ WT KP GGMF+W +P DG
Sbjct: 278 AIEALEHGDAFLETQRELYEKRRNTFVEALQLN-----GWTVSKPGGGMFIWAKIPDDGR 332
Query: 350 DSKKMLEKAVK-KGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETI 404
D+ +++A++ GV PG AF ++ + +R+ E ++R+ +LA+ +
Sbjct: 333 DAMSFVKQAMEHAGVIVTPGHAF--GKEGEGYVRMALVQ-PETELRKAANQLAQIL 385
>pir||B72275 probable aspartate transaminase (EC 2.6.1.1) TM1255 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4981811|gb|AAD36330.1|AE001781_1 (AE001781)
aspartate aminotransferase [Thermotoga maritima]
Length = 377
Score = 97.1 bits (238), Expect = 3e-19
Identities = 91/356 (25%), Positives = 170/356 (47%), Gaps = 25/356 (7%)
Query: 19 KAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGT 78
K ME+ A + + L+K E D+I+L G P+ T P+ +++E + + + ++Y
Sbjct: 13 KTMELDA-KAKALIKKGE--DVINLTAGEPDFPT-PEPVVEEAVRFLQKGE----VKYTD 64
Query: 79 TKGFTPLRETLLDWLEKRYGISKEND-IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYL 137
+G LRE + + +RY D +++T+G++QAL +DPGD VIV +P ++
Sbjct: 65 PRGIYELREGIAKRIGERYKKDISPDQVVVTNGAKQALFNAFMALLDPGDEVIVFSPVWV 124
Query: 138 AALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMS 197
+ + + V N + +E+ L GK ++ P NP GV
Sbjct: 125 SYIPQI-ILAGGTVNVVETFMSKNFQPSLEEVEGLLV-GKTKAVLINSPN--NPTGVVYR 180
Query: 198 EERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA-PG 256
E + L+ LA + + +I D+ Y L Y+ + + + R++Y+ FSK + G
Sbjct: 181 REFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDRIVYINGFSKSHSMTG 240
Query: 257 FRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRD 316
+R+G+++ + + + T C N Q A K L+ + + +K R++
Sbjct: 241 WRVGYLISSEKVATAVSKIQSHTTSCINTVAQYAALK-----ALEVDNSYMVQTFKERKN 295
Query: 317 AMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAV-KKGVAYVPGEAF 371
++E L++ VK+ +PEG +++ + D K E+ + +K VA VPG AF
Sbjct: 296 FVVERLKKM---GVKFVEPEGAFYLFFKVRG--DDVKFCERLLEEKKVALVPGSAF 346
>pir||S76353 probable aspartate transaminase (EC 2.6.1.1) aspC sll0006
[similarity] - Synechocystis sp. (strain PCC 6803)
>gi|1001578|dbj|BAA10205.1| (D64000) aspartate
aminotransferase [Synechocystis sp.]
Length = 394
Score = 96.7 bits (237), Expect = 4e-19
Identities = 98/382 (25%), Positives = 177/382 (45%), Gaps = 47/382 (12%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIM--EEHADKALQYGTTKGFTPLRETLLDWLEKR 96
D+I L G P+ K P+ II+ + E+ E H Y +G R+++ W ++
Sbjct: 36 DLIDLGMGNPDGKA-PQPIIEAAIAELENPESHG-----YPPFEGTQSFRQSITRWYARQ 89
Query: 97 YGISKEND--IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP 154
YG+ + D + GS++ L + +++PGD+V+V P+Y P + + P
Sbjct: 90 YGVDLDPDSEALPLIGSKEGLGHLALAYVNPGDLVLVPTPSY-----------PAHFRGP 138
Query: 155 L----DDNGMNVEALEDELRKL----KAEGKKVKIVY-TVPTFQNPAGVTMSEERRKHLI 205
L + + + A +D L +L +A ++ KI+Y P NP T E + +
Sbjct: 139 LIAGAEIYPIMLSAKDDWLIQLDQIPEAIAQRAKILYFNYP--NNPTTATAPREFYEAIT 196
Query: 206 ELASEYDLIVIEDDPYGELRYSG-KPKKKIKALDKEGRVIYLGTFSKIL-APGFRIGWIV 263
+ A Y ++++ D Y EL + G +P ++ + + T SK G+R+G++V
Sbjct: 197 DWARHYQIMLVHDLCYAELAFDGYQPTSLLEIPGAKDFSVEFHTLSKTYNMAGWRVGFVV 256
Query: 264 GDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALE 323
G+ II+ L K T+L +F V + + +I +R+ Y+ RRD ++ L
Sbjct: 257 GNQEIIQGLRTLK--TNLDYGIFRVVQKAAETALSLPESYIEVVRKRYQERRDFVINGLS 314
Query: 324 EFMPENVKW--TKPEGGMFVWVTLPDGIDSKKM-LEKAVKKGVAYVPGEAFYAYRDVKNT 380
+ + W T + M++WV P G+ S L K GV PG AF +
Sbjct: 315 K-----LGWSITPSQATMYLWVPCPVGMSSTDFALTVLEKTGVVMTPGNAF--GEGGERY 367
Query: 381 MRLNFTYVDEDKIREGVKRLAE 402
+RL+ D D++ E ++R+ +
Sbjct: 368 VRLSL-IADGDRLGEALQRIEQ 388
>pir||A75128 probable transaminase (EC 2.6.1.-) aspB-like2 PAB1810 [similarity]
- Pyrococcus abyssi (strain Orsay)
>gi|5458249|emb|CAB49738.1| (AJ248285) aspartate
aminotransferase (aspB-like2) [Pyrococcus abyssi]
Length = 398
Score = 96.7 bits (237), Expect = 4e-19
Identities = 89/338 (26%), Positives = 160/338 (47%), Gaps = 36/338 (10%)
Query: 54 PKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQ 112
P E +KE + ++E + YG ++G LRE +++ +K+ G++ +D+ +T+
Sbjct: 47 PPEHMKEAYCKAIKEGHN---YYGDSEGLMELREAIVEREKKKNGVNITPDDVRVTAAVT 103
Query: 113 QALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALE---DEL 169
+AL +I +DPGD +++ P+Y FY VP++ + E + D+L
Sbjct: 104 EALQMIFGALLDPGDEILIPGPSYPPYTGLVKFYGG----VPVEYRTIEEEGWQPDIDDL 159
Query: 170 RKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGK 229
RK E K V NP G ++ + +I +A E+D+ V+ D+ Y + Y GK
Sbjct: 160 RKKITERTKAIAVINP---NNPTGALYDKKTLEEIINIAGEHDIPVLSDEIYDLMTYEGK 216
Query: 230 PKKKIKALDKEGRVIYLGTFSKI-LAPGFRIGWI-VGDPGIIRKLEIAKQSTD------L 281
+L K+ VI + SK+ A G+R+G++ DP KL +++ D L
Sbjct: 217 HISP-ASLTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPE--GKLSEVREAIDKLARIRL 273
Query: 282 CTNVFGQ--VVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGM 339
C N Q +A +L+ ++ K++E RRD + + L E + TKP+G
Sbjct: 274 CPNTPAQFAAIAGLRGPMDYLEEYMKKLKE----RRDYIYKRLNEI--PGISTTKPQGAF 327
Query: 340 FVWVTLPDG---IDSKKMLEKAVKKGVAYVPGEAFYAY 374
+++ + +G D + +L+ V +V G F Y
Sbjct: 328 YIFPRIEEGPWKDDKEFVLDVLHNAHVLFVHGSGFGEY 365
>pir||G70010 probable aspartate transaminase (EC 2.6.1.1) yugH [similarity] -
Bacillus subtilis >gi|1934791|emb|CAB07920.1| (Z93934)
unknown [Bacillus subtilis] >gi|2635636|emb|CAB15129.1|
(Z99120) similar to aspartate aminotransferase [Bacillus
subtilis]
Length = 357
Score = 96.3 bits (236), Expect = 5e-19
Identities = 85/317 (26%), Positives = 150/317 (46%), Gaps = 21/317 (6%)
Query: 15 FFSKKAMEMKASEVRELLKLVETSD-IISLAGGLPNPKTFPKEIIKEILIEIMEEHADKA 73
+ S ++K S +R+ L T + +ISL G P+ T ++E I +E+
Sbjct: 4 YLSDYVQQIKPSGIRKFFDLAATMEGVISLGVGEPDFVTAWN--VREASILSLEQGYTS- 60
Query: 74 LQYGTTKGFTPLRETLLDWLEKRYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVIV 131
Y G LRE + +L R+ +S +N++++T G+ QALD+ R ++PG+ VI+
Sbjct: 61 --YTANAGLYSLREEISRYLSNRFDLSYSPDNELIVTVGASQALDIAIRAIVNPGEEVII 118
Query: 132 EAPTYLA--ALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQ 189
P ++A AL + P ++ D G A + E A +K K + + +
Sbjct: 119 PEPCFVAYDALVSLAGGIPVHVHTTA-DKGFKATAADFE----AAVTEKTKAI-LICSPS 172
Query: 190 NPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTF 249
NP G S+E + E A ++D+IV+ D+ Y EL Y + + R + + F
Sbjct: 173 NPTGSVYSKEELNEIAEFAKKHDVIVLADEIYAELTYDEEFTSIAALPGMKERTVVISGF 232
Query: 250 SKILA-PGFRIGWIVGDPGIIRKLEI-AKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKI 307
SK A G+R+G+ P ++R + Q +C Q A + + G D + K+
Sbjct: 233 SKAFAMTGWRLGFAAA-PSLLRDAMLKIHQYAMMCAPAMAQFAALEGLKNGMED--VEKM 289
Query: 308 REFYKPRRDAMLEALEE 324
++ Y+ RR+ +E+L E
Sbjct: 290 KKSYRRRRNLFVESLNE 306
>sp|O87320|AATC_RHIME PUTATIVE AMINOTRANSFERASE AATC
Length = 405
Score = 94.8 bits (232), Expect = 2e-18
Identities = 97/376 (25%), Positives = 173/376 (45%), Gaps = 34/376 (9%)
Query: 38 SDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRY 97
+DII L G P+ T P+ I+ + L E++++ + +Y ++KG LR + +R+
Sbjct: 30 ADIIDLGMGNPDLPT-PQSIVDK-LCEVVQD--PRTHRYSSSKGIPGLRRAQAAYYARRF 85
Query: 98 GI--SKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYI--QV 153
G+ + E ++ T GS++ + + PGD+V+ PTY + AF F + +
Sbjct: 86 GVKLNPETQVVATLGSKEGFANMAQAITAPGDVVLCPNPTY--PIHAFGFLMAGGVIRSI 143
Query: 154 PLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDL 213
++ + LE +R + K + ++ P+ NP + + K +I A ++D+
Sbjct: 144 SVEPDESFFPPLERAVR--HSIPKPLALILNYPS--NPTAQVATLDFYKDVIAFAKKHDI 199
Query: 214 IVIEDDPYGELRYSGKPKKKIKALDKEGRV-IYLGTFSKILA-PGFRIGWIVGDPGIIRK 271
IV+ D Y E+ + P + + V + + SK + PG+R+G+ VG+ +I
Sbjct: 200 IVLSDLAYSEIYFDDAPPPSVLEVPGATDVTVEFTSMSKTFSMPGWRMGFAVGNERLIAA 259
Query: 272 LEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVK 331
L K D QV A + ++ D I ++R YK RRD M+E+ F +
Sbjct: 260 LTRVKSYLDYGAFTPIQVAATQALNGDGSD--IAEVRAIYKRRRDVMVES---FGKAGFE 314
Query: 332 WTKPEGGMFVWVTLPDGID-------SKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLN 384
P MF W +P+ SK ++EKA VA PG F D + +RL
Sbjct: 315 VPPPPATMFAWAKIPEKFRHLGSLEFSKLLVEKA---DVAVAPGIGFGEQGD--DYVRLA 369
Query: 385 FTYVDEDKIREGVKRL 400
+E +IR+ + +
Sbjct: 370 LV-ENEHRIRQAARNI 384
>pir||E83056 probable aminotransferase PA4715 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950974|gb|AAG08101.1|AE004885_6 (AE004885) probable
aminotransferase [Pseudomonas aeruginosa]
Length = 411
Score = 94.0 bits (230), Expect = 3e-18
Identities = 95/371 (25%), Positives = 164/371 (43%), Gaps = 30/371 (8%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
DII L+ G P+ T P I++++ E Y T++G LR + W RY
Sbjct: 37 DIIDLSMGNPDGPT-PPHIVEKLCTVAQREDTHG---YSTSRGIPRLRRAISHWYRDRYD 92
Query: 99 --ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLD 156
I E++ ++T GS++ L + +D GD ++V P+Y + + VPL
Sbjct: 93 VQIDPESEAIVTIGSKEGLAHLMLATLDHGDTILVPNPSYPIHIYGAVIAGAQVRSVPLV 152
Query: 157 DNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVI 216
LE +R+ + + + + + NP + + + ++ LA +YD++V+
Sbjct: 153 PGIDFFNELERAIRESIPKPRMMILGFP----SNPTAQCVELDFFERVVALAKQYDVMVV 208
Query: 217 EDDPYGELRYSGKPKKKIKALD--KEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEI 274
D Y ++ Y G I + K+ V + G+RIG++VG+P ++ L
Sbjct: 209 HDLAYADIVYDGWKAPSIMQVPGAKDIAVEFFTLSKSYNMAGWRIGFMVGNPELVSALAR 268
Query: 275 AKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE--FMPENVKW 332
K D T QV A + EG + + I Y+ RRD +++ L E +M EN
Sbjct: 269 IKSYHDYGTFTPLQVAAIAAL-EGD-QQCVRDIARQYQQRRDVLVKGLREAGWMVEN--- 323
Query: 333 TKPEGGMFVWVTLPDGIDSKKMLEKAVK----KGVAYVPGEAFYAYRDVKNTMRLNFTYV 388
P+ M+VW +P+ LE A K V+ PG F Y D + F +
Sbjct: 324 --PKASMYVWAKIPEPYAHLGSLEFAKKLLQDAKVSVSPGIGFGDYGD----DHVRFALI 377
Query: 389 D-EDKIREGVK 398
+ D++R+ V+
Sbjct: 378 ENRDRLRQAVR 388
>sp|P77434|YFDZ_ECOLI HYPOTHETICAL AMINOTRANSFERASE YFDZ >gi|7447814|pir||H65011 probable
transaminase (EC 2.6.1.-) b2379 [similarity] -
Escherichia coli (strain K-12)
>gi|1788722|gb|AAC75438.1| (AE000326) putative
aminotransferase [Escherichia coli K12]
>gi|1799790|dbj|BAA16249.1| (D90868) PROBABLE ASPARTATE
AMINOTRANSFERASE (EC 2.6.1.1) (TRANSAMINASE A) (ASPAT).
[Escherichia coli]
Length = 412
Score = 93.6 bits (229), Expect = 4e-18
Identities = 96/373 (25%), Positives = 166/373 (43%), Gaps = 34/373 (9%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEI--LIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKR 96
DII + G P+ T P I++++ + + + H Y T++G LR + W + R
Sbjct: 37 DIIDFSMGNPDGAT-PPHIVEKLCTVAQRPDTHG-----YSTSRGIPRLRRAISRWYQDR 90
Query: 97 YG--ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP 154
Y I E++ ++T GS++ L + +D GD V+V P+Y + + VP
Sbjct: 91 YDVEIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVP 150
Query: 155 LDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLI 214
L + LE +R+ + K + + + NP + E + ++ LA YD++
Sbjct: 151 LVEGVDFFNELERAIRESYPKPKMMILGFP----SNPTAQCVELEFFEKVVALAKRYDVL 206
Query: 215 VIEDDPYGELRYSGKPKKKIKALD--KEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKL 272
V+ D Y ++ Y G I + ++ V + G+RIG++VG+ ++ L
Sbjct: 207 VVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSAL 266
Query: 273 EIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE--FMPENV 330
K D T QV A + EG + + I E YK RRD +++ L E +M E
Sbjct: 267 ARIKSYHDYGTFTPLQVAAIAAL-EGD-QQCVRDIAEQYKRRRDVLVKGLHEAGWMVE-- 322
Query: 331 KWTKPEGGMFVWVTLPDGIDSKKMLEKAVK----KGVAYVPGEAFYAYRDVKNTMRLNFT 386
P+ M+VW +P+ + LE A K V PG F Y D + F
Sbjct: 323 ---MPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDT----HVRFA 375
Query: 387 YVD-EDKIREGVK 398
++ D+IR+ ++
Sbjct: 376 LIENRDRIRQAIR 388
>sp|Q58786|YD91_METJA PUTATIVE AMINOTRANSFERASE MT1391 >gi|2127837|pir||F64473 D-alanine
transaminase (EC 2.6.1.21) - Methanococcus jannaschii
>gi|1592038|gb|AAB99401.1| (U67579) putative
aminotransferase [Methanococcus jannaschii]
Length = 418
Score = 93.2 bits (228), Expect = 5e-18
Identities = 86/334 (25%), Positives = 154/334 (45%), Gaps = 28/334 (8%)
Query: 29 RELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYG-TTKGFTPLRE 87
+E +K ++I + G P+ P+ +I ++ E A K G G L++
Sbjct: 35 QEAMKRHPDMELIDMGVGEPDEMADPE------VIRVLCEEAKKWENRGYADNGIQELKD 88
Query: 88 TLLDWLEKRYG---ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFN 144
+ ++EK YG I N+++ + GS+ AL I FI+PGD+ ++ P Y
Sbjct: 89 AVPPYMEKVYGVKDIDPVNEVIHSIGSKPALAYITSAFINPGDVCLMTVPGYPVTATHTK 148
Query: 145 FYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHL 204
+Y + +PL + + LE +K K+ KI+Y + NP G +++ K +
Sbjct: 149 WYGGEVYNLPLLEENDFLPDLESIPEDIK---KRAKILY-LNYPNNPTGAQATKKFYKEV 204
Query: 205 IELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKIL-APGFRIGWIV 263
++ A E ++IV++D YG L Y GKP + D + + + +FSK G+R+ ++V
Sbjct: 205 VDFAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAKEVGVEIHSFSKAFNMTGWRLAFLV 264
Query: 264 GDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRH--IPKIREFYKPRRDAMLEA 321
G+ II+ K + D GQ + + L ++R+ Y+ R M++
Sbjct: 265 GNELIIKAFATVKDNFD-----SGQFIPIQKAGIYCLQHPEITERVRQKYERRLRKMVKI 319
Query: 322 LEEFMPENVKWTKPEGGMFVWVTLP---DGIDSK 352
L E K P G +++V P +GI+ K
Sbjct: 320 LNEV---GFKARMPGGTFYLYVKSPTKANGIEFK 350
>gb|AAG00592.1| (AF289216) alanine aminotransferase [Thermococcus sp. TK1]
Length = 397
Score = 93.2 bits (228), Expect = 5e-18
Identities = 103/379 (27%), Positives = 180/379 (47%), Gaps = 45/379 (11%)
Query: 17 SKKAMEMKAS------EVRELLKLVETSDIISLAGGLPNPKTF-PKEIIKEILIE-IMEE 68
SK+AM ++ + REL K + II L G P F P E +K+ E IME
Sbjct: 5 SKRAMSIEYAIRDVVLPARELEK--QGIKIIKLNIGDPVKFDFQPPEHMKKAYCEAIMEG 62
Query: 69 HADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGD 127
H YG ++G LRE +++ +K+ G+ D+ +T+ +AL I ID G+
Sbjct: 63 HN----YYGDSEGDRELREAIVEREKKKNGVDITPEDVQVTAAVTEALQFIFGALIDGGE 118
Query: 128 IVIVEAPTYLAALQAFNFYE--PKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTV 185
+++ P+Y + FY PK + +++ G + ++D +K+ + K + ++
Sbjct: 119 EILIPGPSYPPYVGLVKFYGGVPKAYRT-VEEEGWQPD-IDDMRKKITEKTKAIAVINP- 175
Query: 186 PTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIY 245
NP G ++ + +I+LA EYDL +I D+ Y + Y GK +L K+ VI
Sbjct: 176 ---NNPTGALYEKKTLQEIIDLAGEYDLPIISDEIYDLMTYEGKHVSP-GSLTKDVPVIV 231
Query: 246 LGTFSKI-LAPGFRIGWI-VGDPGIIRKLEIAKQSTD------LCTNVFGQ--VVAWKYV 295
+ SK+ A G+R+G++ DP KL +++ LC N Q +A
Sbjct: 232 MNGLSKVYFATGWRLGYMYFVDPE--NKLAEVREAIGKLARIRLCPNTPAQKAAIAGLRG 289
Query: 296 SEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDG---IDSK 352
+L+ ++ K++E RRD + + L E MP + KP+G +++ + +G D +
Sbjct: 290 PMDYLEEYMAKLKE----RRDYIYKRLNE-MP-GISTQKPQGAFYIFPKIEEGPWKSDKE 343
Query: 353 KMLEKAVKKGVAYVPGEAF 371
+L+ V +V G F
Sbjct: 344 FVLDVLHNAHVLFVHGSGF 362
>pir||D64385 aspartate transaminase (EC 2.6.1.1) - Methanococcus jannaschii
Length = 377
Score = 92.8 bits (227), Expect = 6e-18
Identities = 108/407 (26%), Positives = 181/407 (43%), Gaps = 38/407 (9%)
Query: 8 MLGNVERFFSKKAMEMKASEVRELLKLV-----ETSDIISLAGGLPNPKTFPKEIIKEIL 62
M N + SK+ + ++ EV ++L L E +I L G P+ T PK I+ E +
Sbjct: 1 MFINGDVMLSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNT-PKPIVDEGI 59
Query: 63 IEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEND-IMITSGSQQALDLIGRV 121
+ E Y ++G LRE + + + +Y D I+IT GS L
Sbjct: 60 KSLKEGKT----HYTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSS 115
Query: 122 FIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKI 181
ID GD V+++ P Y F K + VE+LE+ L K I
Sbjct: 116 IIDDGDEVLIQNPCYPCYKNFIRFLGAKPVFC-----DFTVESLEEAL-----SDKTKAI 165
Query: 182 VYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEG 241
+ P+ NP G + E + E A E +I D+ Y L Y GK I+ +
Sbjct: 166 IINSPS--NPLGEVIDRE----IYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLE 219
Query: 242 RVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHL 300
+ I + FSK+ A G+RIG+++ + II + +Q+ + Q A K E
Sbjct: 220 KTILINGFSKLYAMTGWRIGYVISNDEIIEAILKLQQNLFISAPTISQYAALK-AFEKET 278
Query: 301 DRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVK 360
+R I + + + RR +L+ +++F + P G +V+ + G D ++ K +K
Sbjct: 279 EREINSMIKEFDRRRRLVLKYVKDF---GWEVNNPIGAYYVFPNI--GEDGREFAYKLLK 333
Query: 361 -KGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
K VA PG F + KN +R+++ E+ I+EG++R+ E + +
Sbjct: 334 EKFVALTPGIGFGS--KGKNYIRISYANSYEN-IKEGLERIKEFLNK 377
>gb|AAG19034.1| (AE005003) aspartate aminotransferase; AspB1 [Halobacterium sp.
NRC-1]
Length = 373
Score = 92.4 bits (226), Expect = 8e-18
Identities = 85/366 (23%), Positives = 155/366 (42%), Gaps = 40/366 (10%)
Query: 16 FSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQ 75
FS + ++ S +R + + D I+L G P+ FP + + A A++
Sbjct: 4 FSDRVAQVSISGIRAVFEAAG-EDAINLGLGQPD---FPTP-------DHARQAAVDAIE 52
Query: 76 YGTTKGFTPLRET--LLDWLEKRYGISKENDI-----MITSGSQQALDLIGRVFIDPGDI 128
G G+T R T L+D + +++ + D+ + T+G +AL L +DPGD
Sbjct: 53 SGAADGYTSNRGTAALVDAIVEKHARDQGVDVAPAGVIATAGGSEALHLAMEAHVDPGDE 112
Query: 129 VIVEAPTYLAALQAFNFYEPKYIQVPL-DDNGMNVEALEDELRKLKAEGKKVKIVYTVPT 187
V+ P +++ + +PL DD + E +ED + A + V +
Sbjct: 113 VLFPDPGFVSYDALTRMAGGNPVGLPLRDDLTLAPETVEDHITDDTA-------AFVVNS 165
Query: 188 FQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLG 247
NP G S + +A E+D++ I D+ Y + + G+ + ++ D + V+
Sbjct: 166 PANPTGAVQSPADMRAFARIADEHDVLCISDEVYEHIVFEGEHRSPMEFADTDNVVVVNA 225
Query: 248 TFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVS--EGHLDRHIP 305
G+R+GW+ ++ Q C + Q A +S +G +D +
Sbjct: 226 CSKTYSMTGWRLGWVAASERRAERMLRVHQYVQACASAPAQYAAEAALSGPQGVVDEMVA 285
Query: 306 KIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAY 365
++ RRD +L+ LE + P G + T+PDG +++ V +GV
Sbjct: 286 A----FEARRDVLLDGLEAM---GLDVPTPGGAFYAMPTVPDG-----WIDEVVDRGVVV 333
Query: 366 VPGEAF 371
VPG AF
Sbjct: 334 VPGSAF 339
>sp|Q58097|AAT2_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 2 (TRANSAMINASE A) (ASPAT)
>gi|2826306|gb|AAB98679.1| (U67515) aspartate
aminotransferase (aspB2) [Methanococcus jannaschii]
Length = 370
Score = 91.7 bits (224), Expect = 1e-17
Identities = 106/398 (26%), Positives = 178/398 (44%), Gaps = 38/398 (9%)
Query: 17 SKKAMEMKASEVRELLKLV-----ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHAD 71
SK+ + ++ EV ++L L E +I L G P+ T PK I+ E + + E
Sbjct: 3 SKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNT-PKPIVDEGIKSLKEGKT- 60
Query: 72 KALQYGTTKGFTPLRETLLDWLEKRYGISKEND-IMITSGSQQALDLIGRVFIDPGDIVI 130
Y ++G LRE + + + +Y D I+IT GS L ID GD V+
Sbjct: 61 ---HYTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVL 117
Query: 131 VEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQN 190
++ P Y F K + VE+LE+ L K I+ P+ N
Sbjct: 118 IQNPCYPCYKNFIRFLGAKPVFC-----DFTVESLEEAL-----SDKTKAIIINSPS--N 165
Query: 191 PAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFS 250
P G + E + E A E +I D+ Y L Y GK I+ + + I + FS
Sbjct: 166 PLGEVIDRE----IYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFS 221
Query: 251 KILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIRE 309
K+ A G+RIG+++ + II + +Q+ + Q A K E +R I + +
Sbjct: 222 KLYAMTGWRIGYVISNDEIIEAILKLQQNLFISAPTISQYAALK-AFEKETEREINSMIK 280
Query: 310 FYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAVK-KGVAYVPG 368
+ RR +L+ +++F + P G +V+ + G D ++ K +K K VA PG
Sbjct: 281 EFDRRRRLVLKYVKDF---GWEVNNPIGAYYVFPNI--GEDGREFAYKLLKEKFVALTPG 335
Query: 369 EAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
F + KN +R+++ E+ I+EG++R+ E + +
Sbjct: 336 IGFGS--KGKNYIRISYANSYEN-IKEGLERIKEFLNK 370
>gb|AAF65616.1|AF163769_1 (AF163769) alanine aminotransferase [Pyrococcus furiosus]
Length = 398
Score = 91.7 bits (224), Expect = 1e-17
Identities = 82/333 (24%), Positives = 157/333 (46%), Gaps = 26/333 (7%)
Query: 54 PKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQ 112
P E +KE + ++E + YG ++G LR+ +++ +++ G+ +D+ +T+
Sbjct: 47 PPEHMKEAYCKAIKEGHN---YYGDSEGLPELRKAIVEREKRKNGVDITPDDVRVTAAVT 103
Query: 113 QALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKL 172
+AL LI +DPGD ++V P+Y FY K ++ + ++D +K+
Sbjct: 104 EALQLIFGALLDPGDEILVPGPSYPPYTGLVKFYGGKPVEYRTIEEEDWQPDIDDIRKKI 163
Query: 173 KAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKK 232
K + ++ NP G ++ + ++ +A EY++ VI D+ Y + Y G+
Sbjct: 164 TDRTKAIAVINP----NNPTGALYDKKTLEEILNIAGEYEIPVISDEIYDLMTYEGEHIS 219
Query: 233 KIKALDKEGRVIYLGTFSKI-LAPGFRIGWI-VGDPGIIRKLEIAKQSTD------LCTN 284
+L K+ VI + SK+ A G+R+G++ DP KL +++ D LC N
Sbjct: 220 P-GSLTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPE--NKLSEVREAIDRLARIRLCPN 276
Query: 285 VFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVT 344
Q A ++ G +D ++ + + K RRD + + L E + TKP+G +++
Sbjct: 277 TPAQFAAIAGLT-GPMD-YLKEYMKKLKERRDYIYKRLNEI--PGISTTKPQGAFYIFPK 332
Query: 345 LPDG---IDSKKMLEKAVKKGVAYVPGEAFYAY 374
+ G D + +L+ V +V G F Y
Sbjct: 333 IEVGPWKNDKEFVLDVLHNAHVLFVHGSGFGEY 365
>gb|AAF27693.1|AC018848_10 (AC018848) putative aspartate aminotransferase; 38163-36256
[Arabidopsis thaliana]
Length = 394
Score = 90.9 bits (222), Expect = 2e-17
Identities = 101/383 (26%), Positives = 172/383 (44%), Gaps = 30/383 (7%)
Query: 38 SDIISLAGGLPNPKTFPKEII-----KEILIEIMEEHADKALQ-YGTTKGFTPLRETLLD 91
+ I SL L NP + + ++ ++ L ++ E D + YG +G LR+ LL
Sbjct: 20 AQIRSLMAELTNPMSLAQGVVHWQPPQKALEKVKELVWDPIISSYGPDEGLPELRQALLK 79
Query: 92 WLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYI 151
L + ++ + +M+T+G+ QA + D GD V++ P Y + AF I
Sbjct: 80 KLREENKLTN-SQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNI 138
Query: 152 QV-PLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASE 210
V P + + +A D L + +E K V TV NP+G + E K + ++ +
Sbjct: 139 IVGPGQSDTLYPDA--DWLERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKD 196
Query: 211 YDLIVIEDDPYGELRYSGKPKKKIKALDKEG-RVIYLGTFSKILA-PGFRIGWIVGD--- 265
+I D+ Y Y G +K EG ++ + +FSK G+R+G+I
Sbjct: 197 AGCWLIVDNTYEYFMYDG-----LKHCCVEGDHIVNVFSFSKTYGMMGWRLGYIAYSERL 251
Query: 266 PGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEF 325
G +L + + +C + Q +A + EG +++ K RD + EALE
Sbjct: 252 DGFATELVKIQDNIPICAAIISQRLAVYALEEGS-GWITERVKSLVK-NRDIVKEALEPL 309
Query: 326 MPENVKWTKPEGGMFVWVTLPDG--IDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRL 383
ENVK EG +++W LP+G D K + A + GV +PG A +R+
Sbjct: 310 GKENVK--GGEGAIYLWAKLPEGHRDDFKVVRWLAHRHGVVVIPGCA----SGSPGYLRV 363
Query: 384 NFTYVDEDKIREGVKRLAETIKE 406
+F + E ++R RL + I+E
Sbjct: 364 SFGGLQEVEMRAAAARLRKGIEE 386
>emb|CAB77419.1| (AL160431) aspartate aminotransferase [Streptomyces coelicolor
A3(2)]
Length = 408
Score = 90.9 bits (222), Expect = 2e-17
Identities = 90/325 (27%), Positives = 147/325 (44%), Gaps = 41/325 (12%)
Query: 103 NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDN---G 159
+ I++T+G +QA+ +DPGD VIV AP + ++ ++V D+
Sbjct: 101 SQILVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVEVVADETTGYR 160
Query: 160 MNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDD 219
+ VE LE A +K K+V V NP G E + + A E+ L V+ D+
Sbjct: 161 VTVEQLE------AARTEKTKVVLFVSP-SNPTGAVYGEAETEAIGRWAVEHGLWVLTDE 213
Query: 220 PYGELRYSGKPKKKIKALDKEGR---VIYLGTFSKILAPGFRIGWIVGDPGIIR-KLEIA 275
Y L Y + AL E R ++ G G+R+GW++G +++ +
Sbjct: 214 IYEHLVYGDAVSVSLPALLPELRDKCIVVNGVAKTYAMTGWRVGWVIGPKDVVKAATNLQ 273
Query: 276 KQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKP 335
+T NV Q A VS G+LD + K+RE + RR ++ L E + V +P
Sbjct: 274 SHATSNVANV-SQAAALAAVS-GNLDA-VAKMREAFDRRRQTIVRMLNEI--DGVLCPEP 328
Query: 336 EGGMFVWVTL-------------PDGID-SKKMLEKAVKKGVAYVPGEAFYAYRDVKNTM 381
EG + + ++ D ++ + +LE+A VA VPGEAF +
Sbjct: 329 EGAFYAYPSVKALLGKEIRGKRPQDSVELAALILEEA---EVAVVPGEAF----GTPGYL 381
Query: 382 RLNFTYVDEDKIREGVKRLAETIKE 406
RL++ DED + EGV R+ + + E
Sbjct: 382 RLSYALGDEDLV-EGVSRIQKLLAE 405
>pir||A83171 probable aminotransferase PA3798 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949971|gb|AAG07185.1|AE004798_8 (AE004798) probable
aminotransferase [Pseudomonas aeruginosa]
Length = 382
Score = 90.9 bits (222), Expect = 2e-17
Identities = 85/336 (25%), Positives = 153/336 (45%), Gaps = 22/336 (6%)
Query: 75 QYGTTKGFTPLRETLLDWLEKRYG--ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVE 132
QY G LRE + +E+ YG +S ++++ IT G+ +A+ + + PGD V+V
Sbjct: 56 QYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAIQALVHPGDEVVVL 115
Query: 133 APTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPA 192
P+Y + + + + VPL ++ D R +A G + ++V + T NP+
Sbjct: 116 DPSYDSYEPSVQLAGGRCVHVPLALPDFSI----DWQRMAEAIGPRTRLV-IINTPHNPS 170
Query: 193 GVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDK-EGRVIYLGTFSK 251
G +S E L L + D+ +I D+ Y L + G + + D+ R + +F K
Sbjct: 171 GALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGK 230
Query: 252 IL-APGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREF 310
G++ G++V P + +L Q + C Q Y++ GH H+ ++ F
Sbjct: 231 TYHVTGWKTGYVVAPPALSAELRKVHQYVNFCGVTPLQWALADYMA-GH-PEHLRQLPGF 288
Query: 311 YKPRRDAMLEALEEFMPENVKWTKPEGGMFVWV---TLPDGIDSKKMLEKAVKK-GVAYV 366
Y+ +RD + L + ++T+ G F V + +D M E ++ GVA +
Sbjct: 289 YQAKRDLFCDLL---LDSRFRFTRAPGTYFQCVDYSAIRPDLDDVAMAEWLTREHGVAAI 345
Query: 367 PGEAFYAYRDVKNTMRL-NFTYVD-EDKIREGVKRL 400
P F Y + MRL F Y E+ +R+ ++L
Sbjct: 346 PVSVF--YEKAPDAMRLVRFCYAKREETLRQAAEKL 379
>dbj|BAB07069.1| (AP001518) aspartate aminotransferase [Bacillus halodurans]
Length = 393
Score = 90.9 bits (222), Expect = 2e-17
Identities = 94/369 (25%), Positives = 163/369 (43%), Gaps = 36/369 (9%)
Query: 17 SKKAMEMKASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQ 75
S + ++ S +R L + +IISL G P+ T ++E I ME
Sbjct: 12 STRVQSIQPSGIRRFFDLASKMENIISLGVGEPDFVT--PWNVREASISSMERGFTA--- 66
Query: 76 YGTTKGFTPLRETLLDWLEKRY--GISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEA 133
Y G LRE + +L +R+ G E++I++T G+ +A+D+ R ID GD VIV
Sbjct: 67 YSANAGIIELREAISRYLYERFHIGYDPESEILVTVGASEAIDIGMRAIIDEGDEVIVVE 126
Query: 134 PTYLAALQAFNFYEPKY-----IQVPLD---DNGMNVEALEDELRKLKAEGKKVKIVYTV 185
P++++ Y P + VP+ D V + E + I+
Sbjct: 127 PSFVS-------YAPLVTMAGGVPVPVGTHIDTDFQVTPAQIEAA---ITPRTKAIILCF 176
Query: 186 PTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIY 245
P NP G M +E + + ++ S DLIV D+ Y EL Y G R +
Sbjct: 177 PN--NPTGSIMGKEELEAVAKVISGNDLIVFSDEIYAELTYDGTHVSLASMDGMRERTVL 234
Query: 246 LGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHI 304
+ FSK A G+R+G++ I+ + Q + +C Q A + + G D H
Sbjct: 235 ISGFSKAFAMTGWRLGYVCAPDDILSAMLKIHQYSLMCAPTMAQHGALEALETGMDDVH- 293
Query: 305 PKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEK-AVKKG 362
++ + Y+ RR+ +++ E + P G + + ++ + G+ S++ E+ +++
Sbjct: 294 -RMVQSYRQRRNFVVKTFTEI---GLTCPMPGGAFYAFPSVKETGLTSEEFAERLLMEEH 349
Query: 363 VAYVPGEAF 371
VA VPG F
Sbjct: 350 VAVVPGNVF 358
>sp|Q60013|AAT_STRVG ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447833|pir||T11786 aspartate transaminase (EC
2.6.1.1) - Streptomyces virginiae
>gi|1217910|dbj|BAA09299.1| (D50624) aspartate
aminotransferase [Streptomyces virginiae]
Length = 397
Score = 90.1 bits (220), Expect = 4e-17
Identities = 89/322 (27%), Positives = 151/322 (46%), Gaps = 35/322 (10%)
Query: 103 NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDD-NGMN 161
+ +++T+G +QA+ +DPGD VIV AP + ++ + V D+ G
Sbjct: 90 SQVLVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVDVVADETTGYR 149
Query: 162 VEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDD-- 219
V ++L + E KV +++ P+ NP G SE K + E A+E+ L V+ D+
Sbjct: 150 VSV--EQLEAARTERTKV-VLFVSPS--NPTGSVYSEADAKAIGEWAAEHGLWVLTDEIY 204
Query: 220 ---PYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIR-KLEIA 275
YGE +++ P DK +I G G+R+GW++ +I+ +
Sbjct: 205 EHLVYGEAKFTSLPVLVPALRDK--CIIVNGVAKTYAMTGWRVGWVIAPQDVIKAATNLQ 262
Query: 276 KQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKP 335
+T +NV QV A VS G+LD + ++R+ + RR M++ L E + V P
Sbjct: 263 SHATSNVSNV-AQVAALAAVS-GNLDA-VAEMRKAFDRRRQTMVKMLNEI--DGVFCPTP 317
Query: 336 EGGMFVWVTLPD-------GIDSKKMLEKAV----KKGVAYVPGEAFYAYRDVKNTMRLN 384
EG + + ++ + G + +E A + VA VPGEAF +RL+
Sbjct: 318 EGAFYAYPSVKELLGKEIRGKRPQSSVELAALILDEVEVAVVPGEAF----GTPGYLRLS 373
Query: 385 FTYVDEDKIREGVKRLAETIKE 406
+ DED + EGV R+ + + E
Sbjct: 374 YALGDEDLV-EGVSRIQKLLAE 394
>pir||B81347 aspartate transaminase (EC 2.6.1.1) Cj0762c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968208|emb|CAB73027.1| (AL139076) aspartate
aminotransferase [Campylobacter jejuni]
Length = 389
Score = 90.1 bits (220), Expect = 4e-17
Identities = 92/378 (24%), Positives = 179/378 (47%), Gaps = 32/378 (8%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
DIIS + G P+ T + IK I +E+ K Y G + + + +K
Sbjct: 30 DIISFSAGEPDFDT--PQTIKNAAISAIEKGCGK---YTAVAGIPEVLKAIQTKFKKDNN 84
Query: 99 ISKE-NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP-LD 156
+ E N+I+ G++ +L ++ D VI+ +P +++ + F K + + L+
Sbjct: 85 LDYETNEIITNVGAKHSLFECIECLVEKDDEVIIPSPYWVSYPEMVKFAGGKPVFIEGLE 144
Query: 157 DNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVI 216
+NG + A ++L+K KV ++ + NP G S+E + ++ + V+
Sbjct: 145 ENGFKITA--EQLKKAITAKTKVLMLNSP---SNPVGSIYSKEELTQIAKVLEGTQITVL 199
Query: 217 EDDPYGELRYSGKPKKKIKALDKEG--RVIYLGTFSKILA-PGFRIGWIVGDP----GII 269
D+ Y +LRY G ++ K+ R + + SK A PG+R G++ +
Sbjct: 200 SDEMYEKLRYDGFDFVAFASVSKDALKRTVTINGLSKCGAMPGWRFGYMASKNKALISAV 259
Query: 270 RKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPEN 329
++L+ + ++++C+ + G D+ I K+R+ ++ RR+ L+ L++ N
Sbjct: 260 KRLQ-GQSTSNICSITQHAAIP---ALNGECDKDIEKMRQAFEKRRNLALDILKQI--PN 313
Query: 330 VKWTKPEGGMFVWVTLPD-GIDSKKMLEKAV-KKGVAYVPGEAFYAYRDVKNTMRLNFTY 387
+ KPEG +++V + DS K +K + ++ VA VPG F + RL++
Sbjct: 314 ISVYKPEGAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGVGF----GMDGYFRLSYAT 369
Query: 388 VDEDKIREGVKRLAETIK 405
DE I++G++R+A IK
Sbjct: 370 SDE-LIKKGLERIANFIK 386
>emb|CAC03612.1| (AJ272538) putative aspartate amino transferase [Kluyvera
ascorbata]
Length = 401
Score = 89.7 bits (219), Expect = 5e-17
Identities = 94/376 (25%), Positives = 166/376 (44%), Gaps = 40/376 (10%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEI--LIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKR 96
DII + G P+ T P I++++ + + + H Y T++G LR + W ++R
Sbjct: 37 DIIDFSMGNPDGAT-PPHIVEKLCTVAQRPDTHG-----YSTSRGIPRLRRAISRWYQER 90
Query: 97 YG--ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP 154
Y I E++ ++T GS++ L + +D GD V+V P+Y + + VP
Sbjct: 91 YDVEIDPEDEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVP 150
Query: 155 LDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLI 214
L + LE +R+ + K + + + NP + E + ++ LA YD++
Sbjct: 151 LVEGVDFFNELERAIRESYPKPKMMILGFP----SNPTAQCVELEFFEKVVALAKRYDVL 206
Query: 215 VIEDDPYGELRYSGKPKKKIKALD--KEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKL 272
V+ D Y ++ + G I + ++ V + G+RIG++VG+ ++ L
Sbjct: 207 VVHDLAYADIVFDGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVNAL 266
Query: 273 EIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKW 332
K D T QV A + EG + + I YK RRD +++ L E W
Sbjct: 267 ARIKSYHDYGTFTPLQVAAIAAL-EGD-QQCVLDIAAQYKRRRDVLVKGLHE-----AGW 319
Query: 333 --TKPEGGMFVWVTLPDGID-------SKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRL 383
P+ M+VW +P+ +KKML+ A V PG F Y D +
Sbjct: 320 MVDMPKASMYVWAKIPEQYAHMGSLEFAKKMLQDA---KVCVSPGIGFGDYGDT----HV 372
Query: 384 NFTYVD-EDKIREGVK 398
F ++ D+IR+ ++
Sbjct: 373 RFALIENRDRIRQAIR 388
>dbj|BAA96891.1| (AB018112) tyrosine aminotransferase-like protein [Arabidopsis
thaliana]
Length = 420
Score = 88.9 bits (217), Expect = 9e-17
Identities = 105/385 (27%), Positives = 170/385 (43%), Gaps = 44/385 (11%)
Query: 40 IISLAGGLPNPKTFPKEIIKEILIEIMEE--HADKALQYGTTKGFTPLRETLLDWLEK-- 95
+I L G P+P FP + +E + + + K Y ++ G R+ + ++L
Sbjct: 44 VIPLGHGDPSP--FPSFRTDQAAVEAICDAVRSTKFNNYSSSSGVPVARKAVAEYLSSDL 101
Query: 96 RYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTY--LAALQAFNFYEPKYIQV 153
Y IS ND+ IT+G QA++++ PG +++ PTY + AF E +Y +
Sbjct: 102 SYQISP-NDVHITAGCVQAIEILISALAIPGANILLPRPTYPMYDSRAAFCQLEVRYFDL 160
Query: 154 PLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDL 213
L +NG +V+ D + L A+ K V I+ P NP G S + + + E A + +
Sbjct: 161 -LPENGWDVDL--DGVEAL-ADDKTVAILVINPC--NPCGNVFSRQHLQKIAETACKLGI 214
Query: 214 IVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSK-ILAPGFRIGW--------IVG 264
+VI D+ Y + KP + + VI LG SK PG+R+GW I+
Sbjct: 215 LVIADEVYDHFAFGDKPFVSMAEFAELVPVIVLGAISKRWFVPGWRLGWMVTLDPHGIMK 274
Query: 265 DPGIIRKL-EIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALE 323
D G ++ L + STD T + G A + + E K + E L
Sbjct: 275 DSGFVQTLINVVNMSTDPATFIQG---AMPDIIGNTKEEFFSSKLEMVKKCAEICYEELM 331
Query: 324 EFMPENVKWTKPEGGMFVWVTL--------PDGIDSKKMLEKAVKKGVAYVPGEAFYAYR 375
+ +P KPEG MF V L D +D L K ++ + +PG+A
Sbjct: 332 K-IPCITCPCKPEGSMFTMVKLNFSLLEDISDDLDFCSKLAK--EESMIILPGQAV---- 384
Query: 376 DVKNTMRLNFTYVDEDKIREGVKRL 400
+KN +R+ F V+ + + EG RL
Sbjct: 385 GLKNWLRITFA-VELELLIEGFSRL 408
>pir||F69863 probable transaminase (EC 2.6.1.-) ykrV [similarity] - Bacillus
subtilis >gi|2633729|emb|CAB13231.1| (Z99111) similar to
aspartate aminotransferase [Bacillus subtilis]
Length = 398
Score = 87.8 bits (214), Expect = 2e-16
Identities = 83/377 (22%), Positives = 163/377 (43%), Gaps = 25/377 (6%)
Query: 33 KLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDW 92
KL E D+I+L G P+ T P+ I++E+ + + K Y + +G L+ +
Sbjct: 27 KLAEGHDVINLGQGNPDQPT-PEHIVEEMKRAVADPENHK---YSSFRGSYRLKSAAAAF 82
Query: 93 LEKRYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKY 150
++ YGI E ++ + G + L + + ++PGD ++V P Y + K
Sbjct: 83 YKREYGIDLDPETEVAVLFGGKAGLVELPQCLLNPGDTILVPDPGYPDYWSGVTLAKAKM 142
Query: 151 IQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASE 210
+PL + + +++ + K + + Y NP G + E + + A+E
Sbjct: 143 EMMPLVKDRAFLPDYSSITAEIREQAKLMYLNYP----NNPTGAVATSEFFEDTVRFAAE 198
Query: 211 YDLIVIEDDPYGELRYSG-KPKKKIKALDKEGRVIYLGTFSKIL-APGFRIGWIVGDPGI 268
+ V+ D YG + + G KP ++ + I + T SK G+R+G+ VG+ +
Sbjct: 199 NGICVVHDFAYGAVGFDGCKPLSFLQTEGAKDIGIEIYTLSKTYNMAGWRVGFAVGNASV 258
Query: 269 IRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPE 328
I + + + + Q A + + + + Y+ RR+A + A E
Sbjct: 259 IEAINLYQDHMFVSLFRATQEAAAEALLAD--QTCVAEQNARYESRRNAWITACRE---- 312
Query: 329 NVKW--TKPEGGMFVWVTLPDGIDSKKMLEKAVKK-GVAYVPGEAFYAYRDVKNTMRLNF 385
+ W T P G F W+ +P+G S++ + ++K VA G F Y + + L
Sbjct: 313 -IGWDVTAPAGSFFAWLPVPEGYTSEQFSDLLLEKANVAVAAGNGFGEYGEGYVRVGL-- 369
Query: 386 TYVDEDKIREGVKRLAE 402
E++++E R+ +
Sbjct: 370 -LTSEERLKEAAYRIGK 385
>sp|P39643|AAT2_BACSU PROBABLE ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|629092|pir||S39740 probable transaminase (EC
2.6.1.-) ywfG [similarity] - Bacillus subtilis
>gi|414009|emb|CAA51641.1| (X73124) ipa-85d [Bacillus
subtilis] >gi|2636305|emb|CAB15796.1| (Z99123) alternate
gene name: ipa-85d~similar to aspartate aminotransferase
[Bacillus subtilis]
Length = 399
Score = 87.4 bits (213), Expect = 3e-16
Identities = 96/400 (24%), Positives = 177/400 (44%), Gaps = 32/400 (8%)
Query: 11 NVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHA 70
+V + ++ + +V+E+ K + II+L G P+ T P I+ + E
Sbjct: 7 DVIKTLPRQEFSLVFQKVKEMEKT--GAHIINLGQGNPDLPTPP-----HIVEALREASL 59
Query: 71 DKALQ-YGTTKGFTPLRETLLDWLEKRYG--ISKENDIMITSGSQQALDLIGRVFIDPGD 127
+ + YG +G+ L+E + + ++ YG I+ E ++ + G + L ++ + ++PGD
Sbjct: 60 NPSFHGYGPFRGYPFLKEAIAAFYKREYGVTINPETEVALFGGGKAGLYVLTQCLLNPGD 119
Query: 128 IVIVEAPTYLAALQAFNFYEPKYIQVPL-DDNGMNVEALEDELRKLKAEGKKVKIVYTVP 186
I +V P Y L + ++PL ++NG L D + A +K K+++ +
Sbjct: 120 IALVPNPGYPEYLSGITMARAELYEMPLYEENGY----LPDFEKIDPAVLEKAKLMF-LN 174
Query: 187 TFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYL 246
NP G A E+++ +I D YG + KP ++A D + L
Sbjct: 175 YPNNPTGAVADAAFYAKAAAFAKEHNIHLIHDFAYGAFEFDQKPASFLEAEDAKTVGAEL 234
Query: 247 GTFSKIL-APGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIP 305
+FSK G+R+ + VG+ II+ + + + +FG + + H
Sbjct: 235 YSFSKTFNMAGWRMAFAVGNEKIIQ--AVNEFQDHVFVGMFGGLQQAASAALSGDPEHTE 292
Query: 306 KIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGID-----SKKMLEKAVK 360
++ YK R D E+ + K KP+G +VW +P+ + S +LE A
Sbjct: 293 SLKRIYKERIDFFTALCEKEL--GWKMEKPKGTFYVWAEIPNTFETSHQFSDYLLEHA-- 348
Query: 361 KGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
V PGE F + + K +R++ ED +RE V R+
Sbjct: 349 -HVVVTPGEIFGS--NGKRHVRISMVSKQED-LREFVTRI 384
>pir||H81039 valine--pyruvate aminotransferase NMB1823 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|3299892|gb|AAC25982.1| (AF014804) AvtA [Neisseria
meningitidis] >gi|7227076|gb|AAF42158.1| (AE002531)
valine--pyruvate aminotransferase [Neisseria
meningitidis MC58]
Length = 430
Score = 86.2 bits (210), Expect = 6e-16
Identities = 101/403 (25%), Positives = 176/403 (43%), Gaps = 52/403 (12%)
Query: 43 LAGGLPNPKTFPK--EIIKEILIEIMEEHADKAL-QYGTTKGFTPLRETLLDWLEKRYGI 99
L GG NP P+ + +I ++ EHA + + Y +G L + L +L + Y
Sbjct: 36 LGGG--NPARIPEIDQAFADIFSKLAAEHAVENIGNYSNPQGDAVLIDALTAFLNREYSW 93
Query: 100 SKEND-IMITSGSQQALDLIGRVF-----IDPGD-----IVIVEAPTYLAAL------QA 142
+ D I +T+GSQ A + +F + G I++ AP Y+ Q
Sbjct: 94 NLTADNIALTNGSQNAFFYLFNLFGGKFNLSDGTSAEKAILLPLAPEYIGYADVHVEGQH 153
Query: 143 FNFYEPKYIQVPLDDNG------MNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTM 196
F +PK V + ++ +ALE+ L +LKA GK I + PT NP G +
Sbjct: 154 FVSVKPKIENVEHEGEAGFFKYRVDFDALEN-LPELKA-GKIGAICCSRPT--NPTGNVL 209
Query: 197 SEERRKHLIELASEYDLIVIEDDPYG----ELRYSGKPKKKIKALDKEGRVIYLGTFSKI 252
++ L LA E+ + +I D+ YG + YS L+ +I + SK+
Sbjct: 210 TDGEMARLDALAREHGIPLIIDNAYGMPFPNIIYSDV------TLNWHENIILCFSLSKV 263
Query: 253 LAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK-IREFY 311
PG R G IV P +++ + +L FG +A + G + R + IR FY
Sbjct: 264 GLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRFGAAIATPLLESGEMKRLADQVIRPFY 323
Query: 312 KPRRDAMLEALE-EFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKGVAYVPGE 369
+ + + L+ E +K KPEG +F+W+ + + S+ + E +G +PGE
Sbjct: 324 RNQAQTAVSLLKRELGAYPMKIHKPEGAIFLWLWFENLPVSSQTLYEMLKAEGTLIIPGE 383
Query: 370 AFYA------YRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
F+ Y +R++ D + +G+ + +T+++
Sbjct: 384 HFFVGIDTQDYPHAGECIRMSIAQ-DAQTLEKGIAAIGKTVRK 425
>gb|AAF12702.1|AF035157_1 (AF035157) aspartate aminotransferase [Lactococcus lactis]
Length = 393
Score = 86.2 bits (210), Expect = 6e-16
Identities = 102/358 (28%), Positives = 163/358 (45%), Gaps = 37/358 (10%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
DII L G P+ T PK+I + + I A Q G G L++ + + + Y
Sbjct: 32 DIIDLTLGQPDFPT-PKKIGQAAIEAINNGQASFYTQAG---GLPELKKAVQHYWTRFYA 87
Query: 99 IS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFY--EPKYIQVPL 155
+ N+I+IT+G++ AL +DP D VI+ AP +++ + P ++
Sbjct: 88 YEIQTNEILITAGAKFALYAYFMATVDPLDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQ 147
Query: 156 DDN-GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLI 214
++N + VE LE KA K KI+ + + NP G+ S+E + E A +DL+
Sbjct: 148 ENNFKVTVEQLE------KARTSKTKILL-LNSPSNPTGMIYSKEELTAIGEWAVAHDLL 200
Query: 215 VIEDDPYGELRYSGKPKKKIKALDKE--GRVIYLGTFSKILA-PGFRIGWIVGDPGIIRK 271
++ DD Y L Y+G I +L E R + SK A G+RIG VGDP II
Sbjct: 201 ILADDIYHRLVYNGAEFTAISSLSDEIRNRTTVINGVSKTFAMTGWRIGLAVGDPEIIAA 260
Query: 272 L-EIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENV 330
+ +IA Q+T T V Q A + E D+ K+ ++ R + + L E
Sbjct: 261 MTKIASQTTSNPTAV-AQYAAIEAFEEN--DKSFEKMHAAFEERLNKIYLQLSEV--PGF 315
Query: 331 KWTKPEGGMFVWVTLPDGIDSK----------KMLEKAVKKGVAYVPGEAFYAYRDVK 378
+ KP G +++ + + K +LE+A GVA V G F + +V+
Sbjct: 316 ELVKPNGAFYLFPKVTKAMAMKGYTDVTDFTTAILEEA---GVALVTGAGFGSPENVR 370
>pir||H64603 probable aspartate transaminase (EC 2.6.1.1) P0672 [similarity] -
Helicobacter pylori (strain 26695)
>gi|2313794|gb|AAD07733.1| (AE000580) solute-binding
signature and mitochondrial signature protein (aspB)
[Helicobacter pylori 26695]
Length = 390
Score = 85.0 bits (207), Expect = 1e-15
Identities = 95/386 (24%), Positives = 181/386 (46%), Gaps = 44/386 (11%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
DI+S + G P+ T + IK+ I+ + + K Y G L + + L+K
Sbjct: 31 DILSFSAGEPDFDT--PQAIKDAAIKALNDGFTK---YTPVAGIPELLKAIAFKLKKENN 85
Query: 99 ISKE-NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDD 157
+ E N+I++++G++Q+L + I+ GD VI+ P ++ Y ++
Sbjct: 86 LDYEPNEILVSNGAKQSLFNAIQALIEEGDEVIIPVPFWVT-----------YPELVKYS 134
Query: 158 NGMNVEALEDELRKLKAEGKKVK---------IVYTVPTFQNPAGVTMSEERRKHLIELA 208
G++ DE K K++K ++ T P+ NP G+ S+ + L E+
Sbjct: 135 GGVSQFIQTDEKSHFKITPKQLKDALSPKTKMLILTTPS--NPTGMLYSKAELEVLGEVL 192
Query: 209 SEYDLIVIEDDPYGELRYSGK-PKKKIKALDKEGRVIYLGTFSKILA-PGFRIGWIVGDP 266
+ + V+ D+ Y +L Y G+ + + + R I + SK +A G+R+G+
Sbjct: 193 KDTKVWVLSDEIYEKLVYKGEFVSCAAVSEEMKKRTITISGLSKSVAMTGWRMGYAASKD 252
Query: 267 GIIRKLEIAKQSTDLCTNVFGQV--VAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE 324
+ KL QS CT+ + +A EG +D+ I +R+ ++ R D +
Sbjct: 253 KKLVKLMNNLQSQ--CTSNINSITQMASIVALEGLVDKEIETMRQAFERRCDLAHAKINA 310
Query: 325 FMPENVKWTKPEGGMFVWVTLPD--GIDSKKMLEKAV-KKGVAYVPGEAFYAYRDVKNTM 381
N KP+G ++++ + G DS + + + K+GVA VPG+AF ++ +
Sbjct: 311 IGGLNA--LKPDGAFYLFIHIGSLCGGDSMRFCHELLEKEGVALVPGKAF----GLEGYV 364
Query: 382 RLNFTYVDEDKIREGVKRLAETIKEE 407
RL+F E++I +G++R+A +K +
Sbjct: 365 RLSFA-CSEEQIEKGIERIARFVKSK 389
>pir||D72450 probable aspartate transaminase (EC 2.6.1.1) APE2248 [similarity] -
Aeropyrum pernix (strain K1) >gi|5105949|dbj|BAA81260.1|
(AP000064) 409aa long hypothetical aspartate
aminotransferase [Aeropyrum pernix]
Length = 409
Score = 84.3 bits (205), Expect = 2e-15
Identities = 88/366 (24%), Positives = 166/366 (45%), Gaps = 44/366 (12%)
Query: 66 MEEHADKALQ-----YGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIG 119
+ E A KAL Y T G LRE + +L RYG +++ T+G++ A+ L
Sbjct: 59 IREAAKKALDEGFTGYTETAGIPELREAIAWYLNSRYGADVSPEEVIATTGAKTAIFLGM 118
Query: 120 RVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLD-DNGM----NVEALEDELRKLKA 174
+++ PGD VI+ P+Y A Q + + + VP+ + G+ ++E +E +A
Sbjct: 119 ALYLRPGDEVIIPDPSYYAYAQVAKLFGARPVYVPMKFEPGLGFRFDIEGIE------RA 172
Query: 175 EGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKI 234
+K +++ V NP G ++ + + ++A LI++ D+ Y Y+ KP K
Sbjct: 173 VSEKTRMI-VVNNPHNPTGSVFPPDQVEAIHDIARRRGLIILADEIYDNFLYTEKPFKST 231
Query: 235 KAL-DKEGRVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFG--QVV 290
+L D ++Y+ FSK + G+R+G++V + E+ ++ DL ++ +
Sbjct: 232 LSLPDWRENLVYVNGFSKTFSMTGWRLGYVV------LRREVIPKALDLAVTIYSCPPSI 285
Query: 291 AWKYVSEGHLDRHIPKIREFYKPRRD---------AMLEALEEFMPENVKWTKPEGGMFV 341
A K L +RE + R + E +E ++PE + P +
Sbjct: 286 AQK-AGVAALRGDWGPVREMVEEFRSRARILYDILSQAEGIEPYLPEGAFYMFPRVAGLL 344
Query: 342 WVTLPDGIDSKKMLEKAV-KKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRL 400
T G+ +++ EK + GV +PG +F + +RL+F D ++EG + +
Sbjct: 345 RKT---GLSVEQLAEKLLYSYGVLVLPGTSF-PESVGREHVRLSFATATSD-VKEGAEII 399
Query: 401 AETIKE 406
+E
Sbjct: 400 VRASRE 405
>pir||F83189 probable aminotransferase PA3659 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949820|gb|AAG07047.1|AE004785_11 (AE004785)
probable aminotransferase [Pseudomonas aeruginosa]
Length = 402
Score = 84.3 bits (205), Expect = 2e-15
Identities = 90/372 (24%), Positives = 164/372 (43%), Gaps = 58/372 (15%)
Query: 42 SLAGGLPNPKTF---------PKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDW 92
+L GG P T PK + E + E+ D+ Y TT G LRE + W
Sbjct: 18 ALLGGARPPATLKPIALSIGEPKHRSPSFVAETLAENLDQLAVYPTTLGLPALREAIARW 77
Query: 93 LEKRYGI-----SKENDIMITSGSQQALDLIGRVFI---DPGD---IVIVEAPTYL---- 137
E+R+ + ++ +G+++AL + + +PG+ +V+ P Y
Sbjct: 78 CERRFSVPAGWLDAARHVLPVNGTREALFAFTQTVVRRSEPGEAPGLVVSPNPFYQIYEG 137
Query: 138 AALQAFNFYEPKYIQVPLDDNGMN--VEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVT 195
AAL A P Y+ ++NG N +A+++ A ++ +I++ NP G
Sbjct: 138 AALLAGAV--PHYLPC-REENGFNPDFDAVDE------ATWQRCQILFLCSP-GNPTGAL 187
Query: 196 MSEERRKHLIELASEYDLIVIEDDPYGELRY--SGKPKKKIKALDKEGR------VIYLG 247
+ E K LI LA YD ++ D+ Y EL + + P + A + GR V++
Sbjct: 188 VPLETLKKLIALADRYDFVIAADECYSELYFDENAPPPGLLNACAELGRTDFSRCVVFHS 247
Query: 248 TFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKI 307
+ PG R G++ GD I++K + + V Q+ + ++ + + H+
Sbjct: 248 LSKRSNLPGLRSGFVAGDAEILKKFLLYRTYHGCAMPVQTQLAS---IAAWNDEVHVRAN 304
Query: 308 REFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLP--DGIDSKKMLEKAVKKGVAY 365
R Y+ + DA+L L+ + +P+G ++W P D + ++++ E ++ V
Sbjct: 305 RSLYREKFDAVLAILDGVLDVQ----RPDGSFYLWARTPVDDTVFTRELFE---QQHVTV 357
Query: 366 VPGEAFYAYRDV 377
VPG Y R+V
Sbjct: 358 VPGS--YLSREV 367
>pir||H71909 probable aspartate transaminase (EC 2.6.1.1) aspB [similarity] -
Helicobacter pylori (strain J99)
>gi|4155168|gb|AAD06196.1| (AE001493) ASPARTATE
AMINOTRANSFERASE [Helicobacter pylori J99]
Length = 390
Score = 83.5 bits (203), Expect = 4e-15
Identities = 94/389 (24%), Positives = 183/389 (46%), Gaps = 50/389 (12%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
DI+S + G P+ T + IK+ I+ + + K Y G L + + L+K
Sbjct: 31 DILSFSAGEPDFDT--PQAIKDAAIKALNDGFTK---YTPVAGIPELLKAIAFKLKKENN 85
Query: 99 ISKE-NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDD 157
+ E ++I++++G++Q+L + I GD V++ P ++ Y ++
Sbjct: 86 LDYEPSEILVSNGAKQSLFNAIQALIGEGDEVVIPVPFWVT-----------YPELVKYS 134
Query: 158 NGMNVEALEDELRKLKAEGKKVK---------IVYTVPTFQNPAGVTMSEERRKHLIELA 208
G++ DE K K++K ++ T P+ NP G+ S+ + L E+
Sbjct: 135 GGVSQFIQTDEKSHFKITPKQLKDALSPKTKMLILTTPS--NPTGMLYSKAELEALGEVL 192
Query: 209 SEYDLIVIEDDPYGELRYSGK-PKKKIKALDKEGRVIYLGTFSKILA-PGFRIGWIVGDP 266
+ + V+ D+ Y +L Y G+ + + + R I + SK +A G+R+G+
Sbjct: 193 KDTKVWVLSDEIYEKLVYKGEFVSCAAVSEEMKKRTITINGLSKSVAMTGWRMGYAASKD 252
Query: 267 GIIRKLEIAKQSTDLCTNVFGQV--VAWKYVSEGHLDRHIPKIREFYKPR---RDAMLEA 321
+ KL QS CT+ + +A EG +D+ I +R+ ++ R A + A
Sbjct: 253 KKLVKLMSNLQSQ--CTSNINSITQMASIVALEGLVDKEIETMRQAFEKRCHLAHAKINA 310
Query: 322 LEEFMPENVKWTKPEGGMFVWVTLPD--GIDSKKMLEKAV-KKGVAYVPGEAFYAYRDVK 378
+ E + KP+G ++++ + G DS + + + K+GVA VPG+AF ++
Sbjct: 311 I-----EGLNALKPDGAFYLFINIGSLCGGDSMRFCHELLEKEGVALVPGKAF----GLE 361
Query: 379 NTMRLNFTYVDEDKIREGVKRLAETIKEE 407
+RL+F E++I +G++R+A +K +
Sbjct: 362 GYVRLSFA-CSEEQIEKGIERIARFVKSK 389
>pir||D72220 probable aspartate transaminase (EC 2.6.1.1) TM1698 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4982275|gb|AAD36765.1|AE001810_4 (AE001810)
aspartate aminotransferase [Thermotoga maritima]
Length = 397
Score = 83.5 bits (203), Expect = 4e-15
Identities = 84/340 (24%), Positives = 151/340 (43%), Gaps = 28/340 (8%)
Query: 16 FSKKAMEMKASEVRELLKLVETSD-----IISLAGGLPNPKTFPKEIIKEILIEIMEEHA 70
FS + + + S +R+L+ E + I L G P+ KT E+ E + E+
Sbjct: 4 FSDRVLLTEESPIRKLVPFAEMAKKRGVRIHHLNIGQPDLKT------PEVFFERIYENK 57
Query: 71 DKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIV 129
+ + Y + G LRE + ++R + K ++++T+G +A+ V +PGD +
Sbjct: 58 PEVVYYSHSAGIWELREAFASYYKRRQRVDVKPENVLVTNGGSEAILFSFAVIANPGDEI 117
Query: 130 IVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQ 189
+V P Y A AF + +P+ A+ L E K IV + P
Sbjct: 118 LVLEPFY-ANYNAFAKIAGVKL-IPVTRRMEEGFAIPQNLESFINERTK-GIVLSNPC-- 172
Query: 190 NPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTF 249
NP GV ++ ++L+E+A + L +I D+ Y E+ + G+ + +++ + V+
Sbjct: 173 NPTGVVYGKDEMRYLVEIAERHGLFLIVDEVYSEIVFRGEFASAL-SIESDKVVVIDSVS 231
Query: 250 SKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHL---DRHIPK 306
K A G R+G + I R E+ + L + + S G L D
Sbjct: 232 KKFSACGARVGCL-----ITRNEELISHAMKLAQGRLAPPLLEQIGSVGLLNLDDSFFDF 286
Query: 307 IREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLP 346
+RE Y+ R + +L+ LEE + ++TKP G ++ LP
Sbjct: 287 VRETYRERVETVLKKLEEHGLK--RFTKPSGAFYITAELP 324
>pir||T36548 probable transaminase (EC 2.6.1.-) SCH10.36 [similarity] -
Streptomyces coelicolor >gi|4753882|emb|CAB42045.1|
(AL049754) putative aspartate aminotransferase
[Streptomyces coelicolor A3(2)]
Length = 396
Score = 82.7 bits (201), Expect = 7e-15
Identities = 84/380 (22%), Positives = 158/380 (41%), Gaps = 25/380 (6%)
Query: 7 SMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIM 66
SM + +++ E + E+ L + I+L G P+ T E ++E + +
Sbjct: 3 SMSSSARPLLNRRLAEFGTTIFAEMSALAVRTGAINLGQGFPD--TDGPEEVREAAVRAL 60
Query: 67 EEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEND--IMITSGSQQALDLIGRVFID 124
+ + QY G LR + ++RYG+S + D +++T+G+ +A+ ++
Sbjct: 61 RD--GRGNQYPPGPGVPELRAAVAGHQQRRYGLSYDPDTEVLVTAGATEAIAAALLALLE 118
Query: 125 PGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYT 184
PGD V+ P Y + + V L + DELR + ++ ++ T
Sbjct: 119 PGDEVVALEPYYDSYAACIAMAGGTRVPVTLRPHEGTFRLDLDELRDAVTDRTRLLLLNT 178
Query: 185 VPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKAL-DKEGRV 243
NP G ++ + + ELA E DL+V+ D+ Y L + + + R
Sbjct: 179 P---HNPTGTVLTRDELAAIAELAVERDLLVVTDEVYEHLVFGTAEHIPLASFPGMRERT 235
Query: 244 IYLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQ-STDLCTNVFGQVVAWKYVSEGHLD 301
+ +G+ K + G+++GW+ P ++ + AKQ T + + F VA +
Sbjct: 236 VTIGSAGKTFSFTGWKVGWVTAAPALLTAVRSAKQYLTYVASGPFQYAVAEALALP---E 292
Query: 302 RHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTL-----PDGIDSKKMLE 356
+ R+ + +RD + L E +P G FV + DG + L
Sbjct: 293 SYFAAYRQDMEAKRDLLAAGLAE---AGFGVYRPAGTYFVTTDIRPLGERDGFAFCRSLP 349
Query: 357 KAVKKGVAYVPGEAFYAYRD 376
+ + GV VP FY +R+
Sbjct: 350 E--RAGVVAVPNAVFYNHRE 367
>sp|P09053|AVTA_ECOLI VALINE--PYRUVATE AMINOTRANSFERASE (TRANSAMINASE C) (ALANINE--VALINE
TRANSAMINASE) >gi|1073515|pir||S47793 valine--pyruvate
transaminase (EC 2.6.1.66) avtA [validated] -
Escherichia coli >gi|466710|gb|AAB18549.1| (U00039) o417
[Escherichia coli] >gi|1789996|gb|AAC76596.1| (AE000434)
alanine-alpha-ketoisovalerate (or valine-pyruvate)
transaminase, transaminase C [Escherichia coli K12]
Length = 417
Score = 81.9 bits (199), Expect = 1e-14
Identities = 95/393 (24%), Positives = 167/393 (42%), Gaps = 31/393 (7%)
Query: 35 VETSDIISLAGGLPNPKTFPKEIIKEILIEIME--EHADKALQYGTTKGFTPLRETLLDW 92
+ T I L GG P ++ + +L +++E + D Y +G T L L
Sbjct: 27 LRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGM 86
Query: 93 LEKRYGISKE-NDIMITSGSQQALDLIGRVFIDPG------DIVIVEAPTYLAALQAFNF 145
L ++ G E +I +T+GSQ A + +F ++ AP Y+ A
Sbjct: 87 LREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADA-GL 145
Query: 146 YEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKI-----VYTVPTFQNPAGVTMSEER 200
E ++ N+E L + K + + + I + V NP G +++E
Sbjct: 146 EEDLFVSAR-----PNIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEE 200
Query: 201 RKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIG 260
L L +++ + ++ D+ YG + + G + + L V+ + + SK+ PG R G
Sbjct: 201 LLKLDALGNQHGIPLVIDNAYG-VPFPGIIFSEARPLWNPNIVLCM-SLSKLGLPGSRCG 258
Query: 261 WIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK-IREFYKPRRDAML 319
I+ + II + L G + + + L R I+ FY R +
Sbjct: 259 IIIANEKIITAITNMNGIISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETI 318
Query: 320 EALEEFMPEN-VKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKGVAYVPGEAFYAYRD- 376
+ ++PEN KPEG +F+W+ D I +K++ ++ +GV VPG F+ D
Sbjct: 319 AIIRRYLPENRCLIHKPEGAIFLWLWFKDLPITTKQLYQRLKARGVLMVPGHNFFPGLDK 378
Query: 377 ----VKNTMRLNFTYVDEDKIREGVKRLAETIK 405
MR+N+ + +KI GVK LAE I+
Sbjct: 379 PWPHTHQCMRMNYV-PEPEKIEAGVKILAEEIE 410
>sp|P71348|YFBQ_HAEIN PROBABLE AMINOTRANSFERASE HI0286 >gi|1573250|gb|AAC21948.1|
(U32714) aminotransferase [Haemophilus influenzae Rd]
Length = 404
Score = 81.5 bits (198), Expect = 2e-14
Identities = 70/266 (26%), Positives = 122/266 (45%), Gaps = 17/266 (6%)
Query: 29 RELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRET 88
+E L+L E + I L + NP F E EIL++++ + A Y +KG R+
Sbjct: 23 KEALRLEEEGNKI-LKLNIGNPAPFGFEAPDEILVDVLR-NLPSAQGYCDSKGLYSARKA 80
Query: 89 LLDWLEKRYGI--SKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFY 146
++ + + + GI + ND+ I +G + + + + ++ GD V+V P Y A
Sbjct: 81 IVQYYQSK-GILGATVNDVYIGNGVSELITMAMQALLNDGDEVLVPMPDYPLWTAAVTLS 139
Query: 147 EPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIE 206
K + D++ ++D K+ A+ K + I+ NP G S+E + ++E
Sbjct: 140 GGKAVHYLCDEDANWFPTIDDIKAKVNAKTKAIVIINP----NNPTGAVYSKELLQEIVE 195
Query: 207 LASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKIL-APGFRIGWIV-- 263
+A + +LI+ D+ Y ++ Y G I AL + + L SK GFR GW++
Sbjct: 196 IARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSKAYRVAGFRQGWMILN 255
Query: 264 ----GDPGIIRKLEIAKQSTDLCTNV 285
G I L++ S LC NV
Sbjct: 256 GPKHNAKGYIEGLDML-ASMRLCANV 280
>sp|P23034|AAT_BACSP ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|98167|pir||A38621 aspartate transaminase (EC
2.6.1.1) - Bacillus sp. (strain YM-2)
>gi|142538|gb|AAA22250.1| (M59430) aspartate
aminotransferase [Bacillus sp.]
Length = 392
Score = 81.1 bits (197), Expect = 2e-14
Identities = 92/422 (21%), Positives = 188/422 (43%), Gaps = 51/422 (12%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
+ +K++ + + KA EMKA + D+I L G P+ T P+ I+ +
Sbjct: 5 LANRVKTLTPSTTLAITAKAKEMKAQGI----------DVIGLGAGEPDFNT-PQNIM-D 52
Query: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIG 119
I+ M++ K Y + G L++ +++ ++ + K N+I++ G++ L +
Sbjct: 53 AAIDSMQQGYTK---YTPSGGLPALKQAIIEKFKRDNQLEYKPNEIIVGVGAKHVLYTLF 109
Query: 120 RVFIDPGDIVIVEAPTYLAALQAFNFYE--PKYIQVPLDDNGMNVEALEDELRKLKAEGK 177
+V ++ GD VI+ P +++ + P YI+ + N + ++L+ +
Sbjct: 110 QVILNEGDEVIIPIPYWVSYPEQVKLAGGVPVYIEATSEQN---YKITAEQLKNAITDKT 166
Query: 178 KVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKAL 237
K I+ + NP G+ + E + + ++A E +++++ D+ Y +L Y+G I +
Sbjct: 167 KAVIINSP---SNPTGMVYTREELEDIAKIALENNILIVSDEIYEKLLYNGAEHFSIAQI 223
Query: 238 DKEGR---VIYLGTFSKILAPGFRIGWIVGDPGIIRKL-EIAKQSTDLCTNVFGQVVAWK 293
+E + ++ G G+RIG+ G+ II + ++A ST T
Sbjct: 224 SEEVKAQTIVINGVSKSHSMTGWRIGYAAGNADIINAMTDLASHSTSNPTTASQYAAIEA 283
Query: 294 YVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD------ 347
Y G D + ++R+ ++ R + + L K KP+G ++ LPD
Sbjct: 284 Y--NGPQD-SVEEMRKAFESRLETIYPKLSAI--PGFKVVKPQGAFYL---LPDVSEAAQ 335
Query: 348 --GIDSKKMLEKAV--KKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAET 403
G S A+ + VA +PG F A +T+R+++ + I E ++R+
Sbjct: 336 KTGFASVDEFASALLTEANVAVIPGSGFGA----PSTIRISYA-TSLNLIEEAIERIDRF 390
Query: 404 IK 405
+K
Sbjct: 391 VK 392
>pir||F81983 probable valine--pyruvate transaminase (EC 2.6.1.66) NMA0636
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7379369|emb|CAB83926.1| (AL162753) putative
valine--pyruvate aminotransferase [Neisseria
meningitidis Z2491]
Length = 430
Score = 81.1 bits (197), Expect = 2e-14
Identities = 100/403 (24%), Positives = 174/403 (42%), Gaps = 52/403 (12%)
Query: 43 LAGGLPNPKTFPK--EIIKEILIEIMEEHADKAL-QYGTTKGFTPLRETLLDWLEKRYGI 99
L GG NP P+ I ++ EHA + + Y +G L + L +L + YG
Sbjct: 36 LGGG--NPARIPEIDRAFAGIFSKLAAEHAVENIGNYSNPQGDAVLIDALTAFLNREYGW 93
Query: 100 SKEND-IMITSGSQQALDLIGRVF-----IDPGD-----IVIVEAPTYLAALQA------ 142
+ D I +T+GSQ A + +F + G I++ AP Y+
Sbjct: 94 NLTADNIALTNGSQNAFFYLFNLFGGKFKLSDGTSAEKAILLPLAPEYIGYADVHIEGRH 153
Query: 143 FNFYEPKYIQVPLDDNG------MNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTM 196
F +PK V + ++ +ALE L LK E K I + PT NP G +
Sbjct: 154 FVSVKPKIENVEHEGEAGFFKYRVDFDALES-LPGLKEE-KIGAICCSRPT--NPTGNVL 209
Query: 197 SEERRKHLIELASEYDLIVIEDDPYG----ELRYSGKPKKKIKALDKEGRVIYLGTFSKI 252
++ L LA E+ + +I D+ YG + YS L+ +I + SK+
Sbjct: 210 TDGEMARLDALAREHGIPLIIDNAYGMPFPNIIYSDV------TLNWHENIILCFSLSKV 263
Query: 253 LAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK-IREFY 311
PG R G IV P +++ + +L FG +A + G + R + IR FY
Sbjct: 264 GLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRFGAAIAAPLLESGEMKRLADQVIRPFY 323
Query: 312 KPRRDAMLEALE-EFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKGVAYVPGE 369
+ + + L+ E +K KPEG +F+W+ + + S+ + E +G +PGE
Sbjct: 324 RNQAQTAVSLLKRELGAYPMKIHKPEGAIFLWLWFENLPVPSQTLYEMLKAEGTLIIPGE 383
Query: 370 AFYAYRDVKN------TMRLNFTYVDEDKIREGVKRLAETIKE 406
F+ D ++ +R++ D + + +G+ + +T+++
Sbjct: 384 HFFIGIDTRDYPHAGECIRMSIAQ-DAETLEKGIAAIGKTVRK 425
>emb|CAB45026.1| (AL078635) putative aminotransferase [Amycolatopsis orientalis]
Length = 394
Score = 80.8 bits (196), Expect = 3e-14
Identities = 92/378 (24%), Positives = 157/378 (41%), Gaps = 28/378 (7%)
Query: 41 ISLAGGLPN---PKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRY 97
+ L GLP P++F + + +L +A QY ++G LR + +
Sbjct: 27 VDLTVGLPAFGPPRSFDERLA--MLSSAPHVNARPEDQYAHSRGAIELRAAIAHVYKSEQ 84
Query: 98 GISKEND--IMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPL 155
G+ + D I++T+G+ AL + +PGD V++ P Y+ + +++P
Sbjct: 85 GVDLDPDTQILVTNGAAGALWIAVLTLTEPGDEVLLADPGYMIYPPMIELLGRRVVRIPT 144
Query: 156 DDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIV 215
+ L L++ + V V + NP G SE+ L A E+ L V
Sbjct: 145 SP----ADGFRLHLSDLRSRLTQRSRVVLVNSPGNPTGRVSSEDELADLCAFAVEHGLYV 200
Query: 216 IEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLEI 274
+ D+ Y G + + ALD +G I + SK G+RIGW+ +I +
Sbjct: 201 VHDEVLDRFAY-GIEHRSVVALDHQGVGIAVNGLSKRFGMSGWRIGWLASSSAVIAEAAK 259
Query: 275 AKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTK 334
A L + Q+ A +S+ D + + R + L L +P K T
Sbjct: 260 AHTFFMLAVSHAVQLAAAAALSDPKADGEVSVYAAEIRRRGEVFLADLAR-IPGLGKTTV 318
Query: 335 PEGGMFVWVTLPD-----GIDSKKMLEKAVKK------GVAYVPGEAFYAYRDVKNTMRL 383
P+GG + +V + + GI + AV + GVA VPG F R + +R+
Sbjct: 319 PDGGFYAFVDVGEFARLRGIRVAESTSAAVAEYLLHECGVAVVPGSVF--GRAGEGFVRM 376
Query: 384 NFTYVDEDKIREGVKRLA 401
+F +++ VKRLA
Sbjct: 377 SFA-GSAEQLDRAVKRLA 393
>pir||T21518 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64),
cytosolic F28H6.3 [similarity] - Caenorhabditis elegans
>gi|3876523|emb|CAA20930.1| (AL031621) predicted using
Genefinder~contains similarity to Pfam domain: PF00155
(Aminotransferases class-I), Score=68.4,
E-value=4.8e-17, N=1 [Caenorhabditis elegans]
Length = 437
Score = 80.0 bits (194), Expect = 5e-14
Identities = 80/286 (27%), Positives = 127/286 (43%), Gaps = 25/286 (8%)
Query: 8 MLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPN---PKTFPKEIIKEILIE 64
ML N R S+ E + S E KL + +SL G P+ PK F EI+K+I
Sbjct: 1 MLTNFARQPSENVGEHQESIWVEFGKLAIENKAVSLGQGFPDSPAPK-FVTEILKDIA-- 57
Query: 65 IMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG------ISKENDIMITSGSQQALDLI 118
H +K + T+ F L+ L K Y ++ +DI+IT G+ AL
Sbjct: 58 ---SHPEKIESHQYTRAFG--HPDLVGILSKIYSYFYGVNVNATDDILITVGAYNALYYS 112
Query: 119 GRVFIDPGDIVIVEAPTYLAALQAFNFY--EPKYIQVPLDDNGMNVEALEDELRKLKAEG 176
+I GD VI+ P + F P + + L + + + +L+ +
Sbjct: 113 FLGWISKGDEVIIIEPAFDCYFPQVKFAGGTPISVVMKLKEGSKSASQFTIDFEELEKKI 172
Query: 177 KKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKA 236
K + + NP G S E +H+ ELA YDLIV+ D+ Y E S +PK+ I+
Sbjct: 173 NKRTKMIVINNPHNPTGKLFSREELQHIAELARNYDLIVVADEVY-EFHVS-QPKEMIRF 230
Query: 237 LDKEG---RVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQS 278
G R I +G+ K L+ G+++GW +G ++ L+ Q+
Sbjct: 231 ASLPGMYERTISIGSAGKALSVTGWKLGWAIGPQHLLSPLKTISQN 276
>gb|AAF54707.1| (AE003693) CG6950 gene product [alt 3] [Drosophila melanogaster]
>gi|7299521|gb|AAF54708.1| (AE003693) CG6950 gene
product [alt 1] [Drosophila melanogaster]
>gi|7299522|gb|AAF54709.1| (AE003693) CG6950 gene
product [alt 2] [Drosophila melanogaster]
Length = 417
Score = 77.3 bits (187), Expect = 3e-13
Identities = 101/401 (25%), Positives = 170/401 (42%), Gaps = 56/401 (13%)
Query: 12 VERFFSKKAMEMKASEV-RELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHA 70
+E+F K ++ V E + L ++L G P+ E + L +I +E
Sbjct: 1 MEKFDLPKRLQGSTPSVWNEYIALAMQYKPLNLGQGFPDDAA--PEYVTHSLADIAKEQN 58
Query: 71 DKALQYGTTKGFTPLRETLLDWLEKRYG--ISKE----NDIMITSGSQQALDLIGRVFID 124
QY T+G+ +R L++ L K Y + KE +DI+ITSG+ +AL +D
Sbjct: 59 PLLHQY--TRGYGHVR--LVNALSKLYSGLVGKELNPLSDILITSGAYEALYSTIMGHVD 114
Query: 125 PGDIVIVEAPTYLAALQAFNFYE---------PKYIQVPLDDNGMNVEALEDELRKLKAE 175
GD VI+ P F+ YE P+++ + L + + + L + E
Sbjct: 115 VGDEVIIIEP-------FFDCYEPMVKMAGGVPRFVPLKLRKTEGPISSADWVLDDAEFE 167
Query: 176 ---GKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKK 232
K K++ + T NP G + + + + EL +++++ + D+ Y L + G
Sbjct: 168 SLFNSKTKMI-ILNTPHNPIGKVFNRKELERIAELCRKWNVLCVSDEVYEWLVFDGAEHI 226
Query: 233 KIKAL-DKEGRVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQ-STDLCTNVFGQV 289
+I L R I LG+ K + G++IGW G +IR L++ Q S C +
Sbjct: 227 RICTLPGMWDRTITLGSAGKTFSVTGWKIGWAYGPAELIRNLQMVHQNSVYTCPTPLQEG 286
Query: 290 VAWKYVSE----GHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFV---W 342
VA + E G + + + K +RD M + L E ++ T PEGG F+ W
Sbjct: 287 VARSFEVELARLGQPESYFLSLPRELKQKRDFMAKFLSE---SGMRPTIPEGGYFMLADW 343
Query: 343 VTLPDGIDSKKMLEK----------AVKKGVAYVPGEAFYA 373
L ID +K G+ +P AFY+
Sbjct: 344 SPLAGKIDLSSEPDKHRDYKFTKWMTKNMGLQGIPPSAFYS 384
>sp|Q59228|AAT_BACST ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|1103380|emb|CAA63799.1| (X93600) aspartate
transaminase [Bacillus stearothermophilus]
Length = 393
Score = 75.7 bits (183), Expect = 9e-13
Identities = 88/397 (22%), Positives = 176/397 (44%), Gaps = 50/397 (12%)
Query: 1 MEEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKE 60
+ + + S+ + ++KA E+KA+ D+I L G P+ T P+ I+
Sbjct: 3 LAKRVASLTPSATLAITEKAKELKAAG----------HDVIGLGAGEPDFNT-PQHILDA 51
Query: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKEN-DIMITSGSQQALDLIG 119
+ + E H +Y + G L+E ++ + G+ E ++++ G++ AL +
Sbjct: 52 AIKAMNEGHT----KYTPSGGLPALKEEIIKKFARDQGLDYEPAEVIVCVGAKHALYTLF 107
Query: 120 RVFIDPGDIVIVEAPTYLAALQAFNFYE--PKYIQVPLDDNGMNVEALEDELRKLKAEGK 177
+V +D GD VI+ P +++ + P Y++ L+ N + ++L++
Sbjct: 108 QVLLDEGDEVIIPTPYWVSYPEQVKLAGGVPVYVE-GLEQNHFKITP--EQLKQAITPRT 164
Query: 178 KVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKAL 237
K I+ + NP G+ + E K L E+ + ++++ D+ Y +L Y G I L
Sbjct: 165 KAVIINSP---SNPTGMIYTAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAEL 221
Query: 238 DKEGR---VIYLGTFSKILAPGFRIGWIVGDPGIIRKL-EIAKQSTDLCTNV--FGQVVA 291
E + VI G G+RIG+ G II+ + ++A ST T++ + + A
Sbjct: 222 SPELKAQTVIINGVSKSHSMTGWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAA 281
Query: 292 WKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDG--- 348
+ E + ++R+ ++ R + + + L + KP+G +++ +
Sbjct: 282 YSGPQE-----PVEQMRQAFEQRLNIIYDKLVQI--PGFTCVKPQGAFYLFPNAREAAAM 334
Query: 349 -----IDS--KKMLEKAVKKGVAYVPGEAFYAYRDVK 378
+D +LE+A VA VPG F A +V+
Sbjct: 335 AGCRTVDEFVAALLEEA---KVALVPGSGFGAPDNVR 368
>pir||H69777 transcription regulator GntR family homolog ydeF - Bacillus
subtilis >gi|1881326|dbj|BAA19353.1| (AB001488) SIMILAR
TO HYPOTHETICAL TRANSCRIPTIONAL REGULATORS. [Bacillus
subtilis] >gi|2632818|emb|CAB12325.1| (Z99106) similar
to transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
Length = 465
Score = 75.3 bits (182), Expect = 1e-12
Identities = 70/341 (20%), Positives = 144/341 (41%), Gaps = 14/341 (4%)
Query: 31 LLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLL 90
LL+ + + +I + LP+ ++ + ++ ++ + EE +K YG ++ +
Sbjct: 100 LLEDTKPTHLIEMGAILPDHASY-EPLLYQLKNMVHEEDYEKWFSYGRAGESLWQKDAAV 158
Query: 91 DWLEKRYGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKY 150
+++ + + I+ +G Q A+ PGD + V+ TY + +
Sbjct: 159 KLIQRGGFETSVDHILFANGGQNAIAATLASLCKPGDRIGVDHHTYPGLKTVASLLSVQI 218
Query: 151 IQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASE 210
+ + +++ M+ E+LE + + +K +Y +P + NP MS E R+ + ++ +
Sbjct: 219 VPIKSENDEMSPESLE-----YACKNENIKGLYLIPDYHNPTTSFMSVENRRMVADIVKK 273
Query: 211 YDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIR 270
Y+L VIED Y L + P A +VI++ + SK LAPG R+ ++
Sbjct: 274 YNLFVIEDASYHLLNKNPLP---ALASFAPQQVIHIASLSKSLAPGLRLAYVAVPRQYKE 330
Query: 271 KLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENV 330
+ A + ++ + + + + + I RE R + + + V
Sbjct: 331 PISKALYNLNITVSPLLAELTARTIVSNQFEVLIESHREQTIRRNQLVNRYVAGYTCLGV 390
Query: 331 KWTKPEGGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAF 371
E G+F W+ LP + + E A + GV E F
Sbjct: 391 -----ETGIFRWLLLPGKMSGAEFEELAARLGVQVYAAERF 426
>dbj|BAA75925.1| (AB012002) aspartate aminotransferase [Pyrococcus kodakaraensis]
Length = 364
Score = 75.3 bits (182), Expect = 1e-12
Identities = 86/352 (24%), Positives = 159/352 (44%), Gaps = 47/352 (13%)
Query: 59 KEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGISKENDIMITSGSQQALDLI 118
+EI+ E +E Y +T G LRE + ++ G+S + ++++ G++ LI
Sbjct: 31 REIIEEAVESLRRGETGYTSTGGIRELRERIAEF----EGVSAD-EVIVAPGAKI---LI 82
Query: 119 GRVFIDPGDIVIVEAPTYLAALQAFNFY-EPKYIQVPLDDNGM-NVEALEDELRKLKAEG 176
+ +V +L A F+ E + I+ LD+ + VE ++ +L
Sbjct: 83 AAEIASAKKVAVVSPRWNAYSLIARQFWREVEVIKTTLDERWIPRVEEIKADL------- 135
Query: 177 KKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKA 236
I+ P NP G +S + + L+++A E + V+ D+ Y EL ++ + A
Sbjct: 136 ----IIINYPN--NPTGRVLSGKEIRGLLDVAEENGVKVLSDEVYAELSFT----RFTPA 185
Query: 237 LDKEGRVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYV 295
+ V+ + FSK+ + GFR+G+ +G+ IR+++ +ST C F Q K +
Sbjct: 186 RELYENVVTVKGFSKLYSMTGFRLGYAIGERNEIRRIQRFIESTVTCVPPFVQRAGVKAL 245
Query: 296 SEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGIDSKKML 355
D I ++R Y R + L F + +PEG ++++ P D
Sbjct: 246 E--LRDELIKEVRRAYLERVRMASKMLRGF-----DFVEPEGAFYIFLRTPQ--DGMAFA 296
Query: 356 EKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
E+ + +GVA PG AF D N +R++ + +G++R I+EE
Sbjct: 297 ERLLSRGVAVFPGMAF---GDYPNFIRISLS-------GKGLERGLRVIREE 338
>pir||E82373 valine-pyruvate aminotransferase VC0019 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9654411|gb|AAF93197.1| (AE004094) valine-pyruvate
aminotransferase [Vibrio cholerae]
Length = 418
Score = 75.3 bits (182), Expect = 1e-12
Identities = 88/397 (22%), Positives = 174/397 (43%), Gaps = 37/397 (9%)
Query: 35 VETSDIISLAGGLPNPKTFPK--EIIKEILIEIMEEHA--DKALQYGTTKGFTPLRETLL 90
+ T I L GG NP P + E++ + + + Y +G ++L
Sbjct: 27 LRTPGAIMLGGG--NPAAIPAMLDYFHNTSAEMLADGSLLNAMTNYDGPQGKDVFVKSLA 84
Query: 91 DWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGD------IVIVEAPTYLAALQA- 142
L + YG + E +I +T+GSQ + +F I++ AP Y+ A
Sbjct: 85 TLLRETYGWNISEKNITLTNGSQSGFFYLFNLFAGKQPDGAHKKILLPLAPEYIGYGDAG 144
Query: 143 -----FNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMS 197
F Y P ++ L D G+ ++ +LK + I + PT NP G ++
Sbjct: 145 IDDDIFVSYRP---EIELLDQGLFKYHVD--FSELKVDESVAAICVSRPT--NPTGNVLT 197
Query: 198 EERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGF 257
EE L +LA + + +I D+ YG + + + I+ + ++ + + SK+ PG
Sbjct: 198 EEEIHKLDQLARDNGVPLIIDNAYG-VPFPNIIFEDIEPFWNDNTILCM-SLSKLGLPGL 255
Query: 258 RIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPK-IREFYKPRRD 316
R G ++ + + + L L G + + + +G L R + I+ FY+ +
Sbjct: 256 RCGIVIANEAVTQALTNMNGIISLAPGSMGPALVQRMIEKGDLLRLSEQVIKPFYRQKAQ 315
Query: 317 AMLEALEEFMPE-NVKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKGVAYVPGEAFY-- 372
+E L+ + + + KPEG +F+W+ + I + ++ ++ +GV VPGE F+
Sbjct: 316 HAVELLQSAITDPRFRIHKPEGAIFLWLWFDELPITTMELYQRLKARGVLIVPGEYFFIG 375
Query: 373 ---AYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
+ +R+N+ +E + +G+ +AE +++
Sbjct: 376 QPQEWPHAHECLRMNYVQ-NEQAMEQGIAIIAEEVQK 411
>dbj|BAB05414.1| (AP001512) aspartate aminotransferase [Bacillus halodurans]
Length = 395
Score = 74.9 bits (181), Expect = 2e-12
Identities = 83/378 (21%), Positives = 169/378 (43%), Gaps = 39/378 (10%)
Query: 17 SKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQY 76
S A+ KA E++E + D+I L G P+ T P+ II + + E H +Y
Sbjct: 14 STLAITAKAKELKE-----QGHDVIGLGAGEPDFNT-PQYIIDAAVRSMEEGHT----KY 63
Query: 77 GTTKGFTPLRETLLDWLEKRYGIS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPT 135
+ G L+E +++ ++ G++ +I + +G++ L + + ++ GD VI+ +P
Sbjct: 64 TPSGGLPKLKEAIIEKFKQDQGLTYTAKEIFVGTGAKHVLYTLFQALLNEGDEVIIPSPY 123
Query: 136 YLAALQAFNFY--EPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAG 193
+++ + EP +++ + + +L + + K I+ + NP G
Sbjct: 124 WVSYPEQVKLAGGEPVFVE---GKESNDFKLTPAQLEPVLTDRTKAIIINSP---SNPTG 177
Query: 194 VTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALD---KEGRVIYLGTFS 250
++E L E+ ++++++I D+ Y +L Y G + + KE V+ G
Sbjct: 178 SLYTQEELAALGEVCLKHNVLIISDEIYEKLVYDGAKHTSVAEISPQLKENTVVINGVSK 237
Query: 251 KILAPGFRIGWIVGDPGIIRKL-EIAKQSTDLCTN--VFGQVVAWKYVSEGHLDRHIPKI 307
G+RIG+ G +I+ + +A ST T +G + A Y + D + K+
Sbjct: 238 SHSMTGWRIGYAAGPEALIQAMTNLASHSTSNPTTSAQYGAIAA--YTED---DGSVEKM 292
Query: 308 REFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD--GIDSKKMLEKAVK----- 360
R ++ R + + L V KP+G +++ + + + + ++ VK
Sbjct: 293 RVAFEERLHTIYDKLVAI--PGVSCVKPKGAFYLFPNVEEAAALTGHETVDDFVKVLLEE 350
Query: 361 KGVAYVPGEAFYAYRDVK 378
+ VA VPG F A +V+
Sbjct: 351 EKVALVPGSGFGAPDNVR 368
>sp|Q55128|AAT_SYNY3 ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447809|pir||S74343 probable aspartate transaminase
(EC 2.6.1.1) aspC sll0402 [similarity] - Synechocystis
sp. (strain PCC 6803) >gi|1001121|dbj|BAA10261.1|
(D64001) aspartate aminotransferase [Synechocystis sp.]
Length = 389
Score = 74.1 bits (179), Expect = 3e-12
Identities = 86/376 (22%), Positives = 172/376 (44%), Gaps = 33/376 (8%)
Query: 36 ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEK 95
E D++S G P+ T P I++ + + E +YG G LR+ + L +
Sbjct: 28 EGIDVLSFTAGEPDFTT-PPHIVEAAKLALDEGKT----RYGPAAGEPALRQAIAKKLRE 82
Query: 96 RYGISKEN-DIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP 154
+ + E +I++T+G + +L + I+ GD VI+ AP +L+ + E + V
Sbjct: 83 KNNLPYEAANILVTNGGKHSLFNLMLAMIEQGDEVIIPAPYWLSYPEMVRLAEGTPVIVN 142
Query: 155 LDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEY-DL 213
+ + ++LR+ K ++ + + NP G + + L + EY DL
Sbjct: 143 -TTAATDYKITPEQLRQAITSKSK---LFVLNSPSNPTGAVYTPAEIRALAAVILEYEDL 198
Query: 214 IVIEDDPYGELRYSGKPKKKIKALDKE--GRVIYLGTFSKILA-PGFRIGWIVGDPGIIR 270
V+ D+ Y + Y G I A++ E R I F+K + G+R+G++ G+ +I+
Sbjct: 199 YVVSDEIYERILYDGTEHLSIGAVNDEIFQRTIISNGFAKSYSMTGWRVGYLAGELPLIQ 258
Query: 271 KLEIAK--QSTDLCTNV-FGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMP 327
+ ++++CT +G + A + + + + + + RR ++E + +
Sbjct: 259 ACSTIQGHSTSNVCTFAQYGAIAALE-----NPQTCVETMVKAFTERRQVIVEGINQI-- 311
Query: 328 ENVKWTKPEGGMFVWVTL-PDGIDSKKMLEKAVKK-GVAYVPGEAFYAYRDVKNTMRLNF 385
+ P+G +V+V + G++S + + ++ VA +PG AF A V+ F
Sbjct: 312 AGLSCPNPKGAFYVFVDIAKTGLNSLEFSARLLESHQVAVIPGAAFGADDCVR------F 365
Query: 386 TY-VDEDKIREGVKRL 400
+Y D D I++G+ L
Sbjct: 366 SYATDMDTIKQGLAEL 381
>gi|11498021 aspartate aminotransferase (aspB-4) [Archaeoglobus fulgidus]
>gi|7447816|pir||A69301 probable transaminase (EC
2.6.1.-) aspB4 AF0409 [similarity] - Archaeoglobus
fulgidus >gi|2650220|gb|AAB90825.1| (AE001076) aspartate
aminotransferase (aspB-4) [Archaeoglobus fulgidus]
Length = 386
Score = 74.1 bits (179), Expect = 3e-12
Identities = 79/349 (22%), Positives = 155/349 (43%), Gaps = 30/349 (8%)
Query: 33 KLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKA--LQYGTTKGFTPLRETLL 90
KL E +I G P+ T E ++E ++ A+K +Y + +G RE++
Sbjct: 26 KLQEGVKVIDFGVGDPDLPT------PEHIVEALKNAAEKVERQKYPSYEGMLSFRESVA 79
Query: 91 DWLEKRYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEP 148
+ +R G++ E++++ GS++ + + F++ GD V+V P Y + +
Sbjct: 80 RFYRRRKGVNLDPESEVISLIGSKEGIAHLPLAFVNDGDYVLVPEPGYPVYYSSTLLADG 139
Query: 149 KYIQVPLDDNGM---NVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLI 205
++PL + + + + DE+ +K KI++ + NP +E K I
Sbjct: 140 VPYEMPLKEENKFLPDFQLIPDEI------ARKAKIMF-LNYPNNPTAAVAPKEFIKEAI 192
Query: 206 ELASEYDLIVIEDDPYGELRYSG-KPKKKIKALDKEGRVIYLGTFSKIL-APGFRIGWIV 263
+ + +I+ D Y E+ + G K ++ D + + SK G+RIG+
Sbjct: 193 DFCIDNKIILAHDAAYSEITFDGYKAPSFLEFEDAFEVCVEFNSLSKTYNMTGWRIGFAC 252
Query: 264 GDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALE 323
G+ I+ L K T++ + VF + + DR I + + Y+ RRD ++E L
Sbjct: 253 GNRDILAGL--LKVKTNVDSGVFEAIQEAAIAAMDGPDRVIEENCKVYQRRRDLLVEGLR 310
Query: 324 EFMPENVKWTKPEGGMFVWVTLPDGIDSKKMLEKAV-KKGVAYVPGEAF 371
+ + KP+ +VW + G S + +++ + K G+ PG F
Sbjct: 311 DV---GIDAEKPKATFYVWAKV--GGSSIEFVKQLIDKAGIVATPGIGF 354
>emb|CAB44334.1| (Y17462) cysteine conjugate beta-lyase [Fugu rubripes]
Length = 419
Score = 74.1 bits (179), Expect = 3e-12
Identities = 93/407 (22%), Positives = 162/407 (38%), Gaps = 37/407 (9%)
Query: 30 ELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETL 89
E +L ++L G P+ P + ++E + E QY G PL ++L
Sbjct: 20 EFTQLAAAYSKVNLGQGFPD--FAPPKFVQEAFCHALNE-GPMMHQYTRAFGHVPLVKSL 76
Query: 90 LDWLEKRYG--ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYE 147
+ + G I DI++T G+ QAL + I GD VI+ P +
Sbjct: 77 AKFFSRVIGHEIDPLEDILVTVGAYQALFSAFQALIYEGDEVIIVEPFFDCYQPMVKMAG 136
Query: 148 PKYIQVPLDDNGMNVE------ALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERR 201
+ + +PL G L E K + +V P NP G E
Sbjct: 137 GQPVYIPLRPKGDGSVLSSGDWVLSPEXLAGKFTPRTKALVINTPN--NPLGKVYKTEEL 194
Query: 202 KHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKAL-DKEGRVIYLGTFSKIL-APGFRI 259
+ + +L ++D++VI D+ Y L Y G KI +L R I +G+ K A G+++
Sbjct: 195 QMIADLCIKHDVLVISDEVYEWLTYDGAKHVKIASLPGMWERTITIGSGGKTFSATGWKV 254
Query: 260 GWIVGDPGIIRKLEIAKQSTDL-CTNVFGQVVAWKYVSE----GHLDRHIPKIREFYKPR 314
GW + II+ ++ Q+T C + VA + E G + + ++ +
Sbjct: 255 GWAISSGHIIKHMKTIHQNTVYHCATPAQEAVARGFEREYEVFGTPESYFQQLPAMLHHK 314
Query: 315 RDAMLEALEEFMPENVKWTKPEGGMFVWVTL---------PDGIDSKK---MLEKAVK-K 361
++ + L+ +K PEGG F+ P D K ++ +K K
Sbjct: 315 KNKLASLLKSV---GLKPIMPEGGYFMTADFSSIKVDCDDPSSKDEAKDFRFVKWLIKEK 371
Query: 362 GVAYVPGEAFYAYRDVKNTMR-LNFTYVDEDKIREGVKRLAETIKEE 407
G+A +P AFY+ K + + F +V E+ + + + +E
Sbjct: 372 GLATIPVSAFYSPEHGKEFDKYIRFCFVKEEATLDAAAEILKKWSQE 418
>gb|AAG19132.1| (AE005011) aspartate aminotransferase; AspB2 [Halobacterium sp.
NRC-1]
Length = 380
Score = 73.7 bits (178), Expect = 3e-12
Identities = 84/367 (22%), Positives = 163/367 (43%), Gaps = 26/367 (7%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
D++ L+ G P+ T P+ I+ + H Y + G LR+ + + L+
Sbjct: 31 DVVDLSVGEPDFDT-PESIVDAGKAAMDAGHTG----YAPSNGVPELRDAIAEKLQGDGL 85
Query: 99 ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDN 158
+ ++++T G++QAL + +D GD V + P +++ + +V L +
Sbjct: 86 DYEAGNVIVTPGAKQALYETFQAVVDEGDEVALLDPAWVSYEAMAKLAGGELNRVDLAPH 145
Query: 159 GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIED 218
+E D+L ++ ++ +V + NP G S + + +LA ++D+ VI D
Sbjct: 146 DFQLEPALDDLADAVSDDTELLVVNSP---SNPTGAVYSRAAMEGVRDLAVDHDITVISD 202
Query: 219 DPYGELRYSGKPKKKIKALD-KEGRVIYLGTFSKILA-PGFRIGWIVGDPGIIRKL-EIA 275
+ Y + Y G + LD R + + FSK + G+R+G++ G ++ + ++
Sbjct: 203 EIYQRVNY-GPAHVSLAGLDGMFERTVTINGFSKAYSMTGWRLGYLAGPEALVDQAGKVQ 261
Query: 276 KQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKP 335
S N F Q + + H D I ++ ++ RRD +++ F + P
Sbjct: 262 SHSVSSAAN-FIQRAGVEAIR--HTDDAIDEMVAAFESRRDLLVDL---FAEHGTDVSTP 315
Query: 336 EGGMFVWVTLPDGIDSKKMLEKAVKKG-VAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIR 394
+G ++ + + D D + + A+K VA VPG AF A RL++ D++
Sbjct: 316 DGAFYLMLPVAD--DDQAWCQDALKDAHVATVPGSAFGA----PGYARLSYA-ASTDRLE 368
Query: 395 EGVKRLA 401
V RLA
Sbjct: 369 AAVDRLA 375
>pir||T35706 probable aspartate transaminase (EC 2.6.1.1) SC7H1.11 [similarity]
- Streptomyces coelicolor >gi|2808769|emb|CAA16198.1|
(AL021411) aminotransferase [Streptomyces coelicolor
A3(2)]
Length = 382
Score = 73.0 bits (176), Expect = 6e-12
Identities = 87/370 (23%), Positives = 158/370 (42%), Gaps = 24/370 (6%)
Query: 41 ISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYGIS 100
+SLA G P+ T P +++ + + E H Y +G LR L L +R G +
Sbjct: 30 VSLAMGEPDFPT-PPTVVQAAVSALREGHT----HYADQRGLRELRAALAARLPERPGGA 84
Query: 101 KE-NDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPL-DDN 158
+ +D+++T G+ AL + + PGD V+V P Y VPL D
Sbjct: 85 WDADDVLVTHGATAALAAVVLATVGPGDRVVVPEPAYSLYADLVVLAGGTVDFVPLAPDL 144
Query: 159 GMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIED 218
+++AL L ++++ P+ NP G+ E + L +L D++V+ D
Sbjct: 145 HWDLDALAAAL------PGAAMMIFSNPS--NPTGIVHRREELEALGKLLDGTDVLVVSD 196
Query: 219 DPYGELRYSG-KPKKKIKALDKEGRVIYLGTFSKILA-PGFRIGWIVGDPGIIRKLEIAK 276
+ Y L Y G +P ++ GR +Y+ TFSK A G+R+G++ G ++
Sbjct: 197 EAYHRLAYPGHEPVSALEIESLRGRTVYVQTFSKTYAMTGWRVGYLTGPREVLDAAAQVH 256
Query: 277 QSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPE 336
++ + N Q A + D + + + Y+ RRD ++ L + PE
Sbjct: 257 RTWNGSLNTAVQHAALAALDLP--DGVVGAMADRYRQRRDLVVGRLSGV--PGLHLVPPE 312
Query: 337 GGMFVWVTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDEDKIREG 396
G + ++ D +M+ + + V A Y + +R++F ED + G
Sbjct: 313 GAFYGFLRY-DADRPSEMVARELAACQVLVRAGAEYG-PSGEGHLRISFA-ASEDDLWVG 369
Query: 397 VKRLAETIKE 406
++R+ E
Sbjct: 370 LERIVRYFAE 379
>gi|6320317 Ydr111cp [Saccharomyces cerevisiae]
>gi|1703231|sp|P52892|ALAT_YEAST PUTATIVE ALANINE
AMINOTRANSFERASE (GLUTAMIC--PYRUVIC TRANSAMINASE) (GPT)
(GLUTAMIC--ALANINE TRANSAMINASE) >gi|1077571|pir||S52677
probable membrane protein YDR111c - yeast (Saccharomyces
cerevisiae) >gi|747886|emb|CAA88665.1| (Z48758) unknown
[Saccharomyces cerevisiae]
Length = 507
Score = 71.8 bits (173), Expect = 1e-11
Identities = 92/416 (22%), Positives = 177/416 (42%), Gaps = 58/416 (13%)
Query: 2 EEEIKSMLGNVERFFSKKAMEMKASEVRELLKLVETSDIISLAGG-LPNPKTFPKEIIKE 60
++ I + +GN ++ K + R++L ++E +I+ + L + F ++ + E
Sbjct: 67 DDIINANIGNPQQLDQKPL-----TFTRQVLAILEYPEILRVGHNELASLNLFSRDAL-E 120
Query: 61 ILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG--ISKENDIMITSG-SQQALDL 117
++ + Y ++G +R+T+ D++ +R G + DI +T+G S A L
Sbjct: 121 RAERLLNDIGGSIGAYSHSQGVPGIRQTVADFITRRDGGEPATPEDIYLTTGASSAATSL 180
Query: 118 IGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGK 177
+ + D +++ P Y + + + + + LD+ N DE+ K+ +
Sbjct: 181 LSLLCKDSQTGLLIPIPQYPLYTASASLFNAQVLPYYLDEES-NWSTNSDEIEKVVQDAL 239
Query: 178 KVKI---VYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKI 234
K +I V V NP G +SEE + +A++Y + +I D+ Y E ++ +
Sbjct: 240 KKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKYGITIISDEVYQENIFNDVKFHSM 299
Query: 235 KALDKEGRVIYLGTFSKI-------LAPGF------RIGW--IVGDPGIIRKLEIAKQST 279
K + ++ + +Y G F + ++ GF R G+ I+G IR S
Sbjct: 300 KKVLRKLQHLYPGKFDNVQLASLHSISKGFMDECGQRGGYMEIIGFSQEIRDALFKLMSI 359
Query: 280 DLCTNVFGQVVAWKYV------SEGHLDRHIPKIREFYKPRRDAML--EALEEFMPENVK 331
+C+ V GQ V V E + H +++ F++ R A L E +E E ++
Sbjct: 360 SICSVVTGQAVVDLMVKPPQPGDESYEQDHDERLKIFHEMRTRANLLYETFKEL--EGIE 417
Query: 332 WTKPEGGMFVWVTL----------------PDGIDSKKMLEKAVKKGVAYVPGEAF 371
KP+G M+++ L PD +LE G+ VPG F
Sbjct: 418 CQKPQGAMYLFPRLVLPKKALCESERLGIEPDEFYCTSLLEST---GICTVPGSGF 470
>pir||D75496 aspartate transaminase (EC 2.6.1.1) DR0623 [similarity] -
Deinococcus radiodurans (strain R1)
>gi|6458322|gb|AAF10201.1|AE001920_4 (AE001920)
aspartate aminotransferase [Deinococcus radiodurans]
Length = 388
Score = 71.8 bits (173), Expect = 1e-11
Identities = 87/374 (23%), Positives = 155/374 (41%), Gaps = 28/374 (7%)
Query: 39 DIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETLLDWLEKRYG 98
D+IS++ G P+ T P +K I +EE K Y G LRE + + G
Sbjct: 35 DVISMSVGEPDFDTPPH--VKAAGIAAIEEGKTK---YTPVSGIPELREAISAKFRRENG 89
Query: 99 IS-KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYEPKYIQVP-LD 156
+ N + +TSG +QAL ++PGD V++ AP +++ + + VP
Sbjct: 90 LDYAPNAVTVTSGGKQALFNAFFALLNPGDEVLIPAPHWVSYPEMVALTGAVPVTVPTTP 149
Query: 157 DNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIELASEYDLIVI 216
G ++ D L ++ I+ + NP G E + + +LA+++ L+++
Sbjct: 150 QQGFQLD--PDALAAAITPRTRMVILNSP---GNPTGAVFPPETLRAVADLATQHGLMIV 204
Query: 217 EDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILAPGFRIGWIVGDPGIIRKLE-IA 275
D+ Y L Y + + I E + G G+RIG+ G +I + +
Sbjct: 205 TDEIYEHLVYDAE-QVSIGTYAPEHTLTINGASKAYAMTGWRIGYAGGPREVIAAMNALQ 263
Query: 276 KQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKP 335
QST ++V R I + R Y+ RRD ++ L + P
Sbjct: 264 SQSTSNASSVSQYAALAALEQHEETMRFIDRARTAYRERRDRIVAGLNAL---GLPTPTP 320
Query: 336 EGGMFVWVTL----PDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYVDED 391
+G +V D +++ +++ + VA VPG F A +RL++ D
Sbjct: 321 QGAFYVMADTRAIHTDELEAARIILDEAQ--VAVVPGTDFAA----PGQVRLSYA-TSMD 373
Query: 392 KIREGVKRLAETIK 405
I E ++RL ++
Sbjct: 374 NIEEVLRRLEGVVR 387
>gb|AAF27157.1|AC016529_20 (AC016529) putative alanine aminotransferase; 79592-76658
[Arabidopsis thaliana]
>gi|9082268|gb|AAF82781.1|AF275371_1 (AF275371) alanine
aminotransferase [Arabidopsis thaliana]
Length = 540
Score = 71.8 bits (173), Expect = 1e-11
Identities = 86/372 (23%), Positives = 153/372 (41%), Gaps = 57/372 (15%)
Query: 76 YGTTKGFTPLRETLLDWLEKRYGISKE-NDIMITSGSQQALDLIGRVFIDPG-DIVIVEA 133
Y ++G LR+ + +E R G + NDI +T G+ A+ ++ ++ + D ++
Sbjct: 170 YSHSQGIKGLRDVIAAGIEARDGFPADPNDIFLTDGASPAVHMMMQLLLSSEKDGILSPI 229
Query: 134 PTYLAALQAFNFYEPKYIQVPLDDN---GMNVEALEDELRKLKAEGKKVKIVYTVPTFQN 190
P Y + + + LD+ G+ + L+ +L + +++G V+ + + N
Sbjct: 230 PQYPLYSASIALHGGSLVPYYLDEATGWGLEISDLKKQLEEARSKGISVRALVVINP-GN 288
Query: 191 PAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFS 250
P G ++EE ++ ++ + L+++ D+ Y E Y P KK + K R + G
Sbjct: 289 PTGQVLAEENQRDIVNFCKQEGLVLLADEVYQENVY--VPDKKFHSFKKVARSLGYGEKD 346
Query: 251 KILAP------------GFRIGW--IVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVS 296
L G R G+ + G +R+ S +LC+N+ GQ++A +S
Sbjct: 347 ISLVSFQSVSKGYYGECGKRGGYMEVTGFTSDVREQIYKMASVNLCSNISGQILASLVMS 406
Query: 297 EGHLDRHIPKIREFYKPRRDAML-------EALEEFMP--ENVKWTKPEGGMFVW----- 342
+ + Y RD +L + LE+ + E V + EG M+++
Sbjct: 407 P---PKPGDDSYDSYMAERDGILSSMAKRAKTLEDALNSLEGVTCNRAEGAMYLFPRINL 463
Query: 343 -----------VTLPDGIDSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTMRLNFTYV-DE 390
T PD K++L GV VPG F V T T + E
Sbjct: 464 PQKAIEAAEAEKTAPDAFYCKRLLNAT---GVVVVPGSGF---GQVPGTWHFRCTILPQE 517
Query: 391 DKIREGVKRLAE 402
DKI V RL E
Sbjct: 518 DKIPAIVNRLTE 529
>pir||H75379 conserved hypothetical protein - Deinococcus radiodurans (strain
R1) >gi|6459342|gb|AAF11140.1|AE002001_6 (AE002001)
conserved hypothetical protein [Deinococcus radiodurans]
Length = 452
Score = 71.0 bits (171), Expect = 2e-11
Identities = 76/297 (25%), Positives = 130/297 (43%), Gaps = 28/297 (9%)
Query: 129 VIVEAPTY---LAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTV 185
+IV P Y L+ F K + V + D+G +V+A+E +L A VK + V
Sbjct: 153 MIVTVPGYDRHFLLLETLGF---KLLAVDMQDDGPDVDAIE----RLAANDASVKGILFV 205
Query: 186 PTFQNPAGVTMSEERRKHLIEL-ASEYDLIVIEDDPYGELRYSGKPKKKIK----ALDKE 240
PT+ NP G T+S E+ + L+ L A+ D + DD Y G+ ++ + AL ++
Sbjct: 206 PTYSNPGGETISAEKARRLVGLKAAAPDFTIFADDAYRAHHLFGEGERDVPVNFVALCRD 265
Query: 241 G----RVIYLGTFSKILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVS 296
R + SKI G +G++ I L + + N F Q K++
Sbjct: 266 AGHPDRAFVFASTSKITFAGAGLGFVGSSEDNIGWLGKYLGAQSIGPNKFEQARHVKFLE 325
Query: 297 ------EGHLDRHIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPDGID 350
EG + H I ++ DA+ L E W P GG F+ + D +
Sbjct: 326 GYDGGLEGLMRDHAALIAPKFQAVYDALSAGLGEGGGGYATWRTPRGGYFISLDTVDPV- 384
Query: 351 SKKMLEKAVKKGVAYVPGEAFY-AYRDVKN-TMRLNFTYVDEDKIREGVKRLAETIK 405
++++++ A + G++ P A Y D KN +RL T ++ E ++ +A +K
Sbjct: 385 AERVVQLADEAGISLTPAGATYPGGNDPKNANIRLAPTRPPLAEVEEAMRGVATCVK 441
>emb|CAC04464.1| (AL391572) conserved hypothetical protein [Neurospora crassa]
Length = 465
Score = 71.0 bits (171), Expect = 2e-11
Identities = 87/370 (23%), Positives = 148/370 (39%), Gaps = 53/370 (14%)
Query: 75 QYGTTKGFTPLRETLLDWLEKRYG--ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVE 132
QY T+G LR+ L +G + E +I IT+G+ + + FI+PGD VIV
Sbjct: 107 QYSPTRGRPRLRKALSKAYAPHWGRELDPETEITITTGANEGMLSAFMAFIEPGDEVIVF 166
Query: 133 APTYLAALQAFNFYEPKYIQVPL----DDNGMNVEALE-----DELRKLKAEGKKVKIVY 183
P + + K + VP+ + + + A E DEL + K+ ++
Sbjct: 167 EPFFDQYISNIEMPGGKIVYVPMHPPKEGHIKTLSASEWTIDFDELERAVTPRTKMLVIN 226
Query: 184 TVPTFQNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRV 243
T NP G S + + EL + +I++ D+ Y L Y+ + + + E
Sbjct: 227 TP---HNPVGKVFSRAELERIAELCVKNQIIILSDEVYDRLFYTPFTRMATLSPEVEKIT 283
Query: 244 IYLGTFSK-ILAPGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDR 302
+ +G+ K A G+R+GW++G +I+ +A T +C + + + D+
Sbjct: 284 LTVGSAGKNFYATGWRVGWLMGPAELIQ--YVAAAHTRICYSSVSPLQEACAIGFEEADQ 341
Query: 303 HIPKIREFYKPRRDAMLEALEEFMPENVKWTK-------PEGGMFVW-----VTLPDGI- 349
+ F+ + M + F N W + PEGG FV V +P+G
Sbjct: 342 -----QGFWTQCIEDMQNKMSRF---NAIWDELGLPYSIPEGGYFVMANLNKVEIPEGYP 393
Query: 350 ----------DSKKMLEKAVKKGVAYVPGEAFYAYRDVKNTM---RLNFTYVDEDKIREG 396
D K + GVA +P FY DV + L F D++ E
Sbjct: 394 FPPHVAERPRDFKLAWFLIQELGVAAIPPSEFYT--DVNAHIVEDWLRFAVCKPDEVLED 451
Query: 397 VKRLAETIKE 406
K +K+
Sbjct: 452 AKERLRGLKK 461
>gi|4757928 cytoplasmic cysteine conjugate-beta lyase; glutamine transaminase
K; kynurenine aminotransferase; glutamine-phenylpyruvate
transaminase; glutamine-phenylpyruvate aminotransferase
[Homo sapiens] >gi|11427802|ref|XP_005366.1| cysteine
conjugate-beta lyase; cytoplasmic (glutamine
transaminase K, kyneurenine aminotransferase) [Homo
sapiens] >gi|1082403|pir||S52790
kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64),
cytosolic [similarity] - human >gi|2146953|pir||S69001
glutamine--phenylpyruvate aminotransferase (EC 2.6.1.64)
- human >gi|758591|emb|CAA57702.1| (X82224)
glutamine--phenylpyruvate aminotransferase [Homo
sapiens]
Length = 422
Score = 70.6 bits (170), Expect = 3e-11
Identities = 91/386 (23%), Positives = 158/386 (40%), Gaps = 61/386 (15%)
Query: 30 ELLKLVETSDIISLAGGLPN--PKTFPKEIIKEILIEIMEEHADKAL-QYGTTKGFTPLR 86
E +KL D+++L G P+ P F E + + D L QY T G+ PL
Sbjct: 20 EFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAV------SGDFMLNQYTKTFGYPPLT 73
Query: 87 ETLLDWLEKRYG--ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFN 144
+ L + + G I ++++T G AL + +D GD VI+ P F+
Sbjct: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPF-------FD 126
Query: 145 FYEPKYIQV------------PLDDNGMNVEALEDELRKLKAEGKKVK----IVYTVPTF 188
YEP + P+ NG + +L ++ GK +V P
Sbjct: 127 CYEPMTMMAGGRPVFVSLKPGPIQ-NGELGSSSNWQLDPMELAGKFTSRTKALVLNTPN- 184
Query: 189 QNPAGVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKAL-DKEGRVIYLG 247
NP G S E + + L ++D++ I D+ Y + Y G I +L R + +G
Sbjct: 185 -NPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243
Query: 248 TFSKIL-APGFRIGWIVGDPGIIRKLEIAKQSTDL-CTNVFGQVVAWKYVSEGHLDR--- 302
+ K A G+++GW++G I++ L Q++ C VA + E L R
Sbjct: 244 SAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303
Query: 303 -HIPKIREFYKPRRDAMLEALEEFMPENVKWTKPEGGMFV----------WVTLPDGID- 350
+ + + + RD M+ +L+ +K P+G F+ LP +D
Sbjct: 304 SYFVQFPQAMQRCRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360
Query: 351 --SKKMLEKAVK-KGVAYVPGEAFYA 373
++ ++ +K KG+ +P FY+
Sbjct: 361 PYDRRFVKWMIKNKGLVAIPVSIFYS 386
>sp|P77727|YFBQ_ECOLI PROBABLE AMINOTRANSFERASE YFBQ >gi|7447846|pir||H65000 probable
transaminase (EC 2.6.1.-) b2290 [similarity] -
Escherichia coli (strain K-12)
>gi|1788627|gb|AAC75350.1| (AE000318) putative
aminotransferase [Escherichia coli K12]
>gi|1799660|dbj|BAA16127.1| (D90860) ASPARTATE
AMINOTRANSFERASE (EC 2.6.1.1) (TRANSAMINASE A) (ASPAT).
[Escherichia coli]
Length = 405
Score = 69.5 bits (167), Expect = 7e-11
Identities = 87/370 (23%), Positives = 157/370 (41%), Gaps = 36/370 (9%)
Query: 22 EMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKG 81
+++ ++E +L E + + L + NP F + EIL++++ + A Y +KG
Sbjct: 16 DIRGPVLKEAKRLEEEGNKV-LKLNIGNPAPFGFDAPDEILVDVIR-NLPTAQGYCDSKG 73
Query: 82 FTPLRETLLDWLEKR--YGISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAA 139
R+ ++ + R ++ E DI I +G + + + ++ GD ++V AP Y
Sbjct: 74 LYSARKAIMQHYQARGMRDVTVE-DIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLW 132
Query: 140 LQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEE 199
A + K + D++ L+D K+ + + I+ NP G S+E
Sbjct: 133 TAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINP----NNPTGAVYSKE 188
Query: 200 RRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKIL-APGFR 258
++E+A +++LI+ D+ Y ++ Y I L + I SK GFR
Sbjct: 189 LLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFR 248
Query: 259 IGWIVGD------PGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYK 312
GW+V + G I LE+ S LC NV Q A + G+ I EF
Sbjct: 249 QGWMVLNGPKKHAKGYIEGLEML-ASMRLCANVPAQ-HAIQTALGGY-----QSISEFIT 301
Query: 313 P------RRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-----GIDSKKMLEKAVKK 361
P +R+ E + + V KP G ++++ + D K +L+ +++
Sbjct: 302 PGGRLYEQRNRAWELINDI--PGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQE 359
Query: 362 GVAYVPGEAF 371
V V G AF
Sbjct: 360 KVLLVQGTAF 369
>gb|AAF07797.1|AC010704_22 (AC010704) putative aminotransferase; 101422-99564 [Arabidopsis
thaliana]
Length = 440
Score = 69.5 bits (167), Expect = 7e-11
Identities = 84/400 (21%), Positives = 165/400 (41%), Gaps = 27/400 (6%)
Query: 17 SKKAMEMKASEVRELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQY 76
+K+ + K + ++ L I+L G PN + +KE I+ +++ + QY
Sbjct: 58 AKRLEKFKTTIFTQMSILAVKHGAINLGQGFPNFDG--PDFVKEAAIQAIKDGKN---QY 112
Query: 77 GTTKGFTPLRETLLDWLEKRYG--ISKENDIMITSGSQQALDLIGRVFIDPGDIVIVEAP 134
G L + + G + E ++ +TSG +A+ I+PGD VI+ AP
Sbjct: 113 ARGYGIPQLNSAIAARFREDTGLVVDPEKEVTVTSGCTEAIAAAMLGLINPGDEVILFAP 172
Query: 135 TYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGV 194
Y + + K + L ++ L +LKA + T NP G
Sbjct: 173 FYDSYEATLSMAGAKVKGITLRPPDFSI-----PLEELKAAVTNKTRAILMNTPHNPTGK 227
Query: 195 TMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKILA 254
+ E + + L E D++V D+ Y +L + R + + + K +
Sbjct: 228 MFTREELETIASLCIENDVLVFSDEVYDKLAFEMDHISIASLPGMYERTVTMNSLGKTFS 287
Query: 255 -PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNVFGQVVAWKYVSEGHLDRHIPKIREFYKP 313
G++IGW + P + + A T+ Q A + + + +++ Y
Sbjct: 288 LTGWKIGWAIAPPHLTWGVRQAHSYLTFATSTPAQWAAVAALKAP--ESYFKELKRDYNV 345
Query: 314 RRDAMLEALEEFMPENVKWTK-PEGGMFVWVT--LPDGIDSK-KMLEKAVKK-GVAYVPG 368
+++ +++ L+E V +T P G + V P G+++ E +++ GV +P
Sbjct: 346 KKETLVKGLKE-----VGFTVFPSSGTYFVVADHTPFGMENDVAFCEYLIEEVGVVAIPT 400
Query: 369 EAFYAY-RDVKNTMRLNFTYVDEDKIREGVKRLAETIKEE 407
FY + KN +R F DE+ +R ++R+ + +K +
Sbjct: 401 SVFYLNPEEGKNLVRFAFC-KDEETLRGAIERMKQKLKRK 439
>pir||B70815 probable transaminase (EC 2.6.1.-) Rv0858c [similarity] -
Mycobacterium tuberculosis (strain H37RV)
>gi|2916917|emb|CAA17664.1| (AL022004) hypothetical
protein Rv0858c [Mycobacterium tuberculosis]
Length = 397
Score = 69.1 bits (166), Expect = 9e-11
Identities = 91/389 (23%), Positives = 151/389 (38%), Gaps = 32/389 (8%)
Query: 30 ELLKLVETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKALQYGTTKGFTPLRETL 89
E+ L ++L G P+ PK +L + A QY G PLR +
Sbjct: 16 EMSALATRIGAVNLGQGFPDEDGPPK-----MLQAAQDAIAGGVNQYPPGPGSAPLRRAI 70
Query: 90 LDWLEKRYGIS--KENDIMITSGSQQALDLIGRVFIDPGDIVIVEAPTYLAALQAFNFYE 147
+ +G+ E ++++T G+ +A+ ++PG V++ P Y +
Sbjct: 71 AAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAG 130
Query: 148 PKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPAGVTMSEERRKHLIEL 207
+ VPL +G D LR+ + I+ + NP G +S + E+
Sbjct: 131 AHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSP---HNPTGAVLSATELAAIAEI 187
Query: 208 ASEYDLIVIEDDPYGELRYSGKPKKKIKALD-KEGRVIYLGTFSKIL-APGFRIGWIVGD 265
A +L+VI D+ Y L + + D R I + + +K+ G++IGW G
Sbjct: 188 AVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGP 247
Query: 266 PGIIRKLEIAKQSTDLCTNV-FGQVVAWKYVSEGHLDRHIPKIREFYKPRRDAMLEALEE 324
+I + AKQ F VA +E D + +R + RRD + L E
Sbjct: 248 AELIAGVRAAKQYLSYVGGAPFQPAVALALDTE---DAWVAALRNSLRARRDRLAAGLTE 304
Query: 325 FMPENVKWTKPEGGMFVWV-TLPDGIDSKKMLEKAV--KKGVAYVPGEAF--------YA 373
G F+ P G D A+ K GVA +P AF
Sbjct: 305 I---GFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQ 361
Query: 374 YRDVKNTMRLNFTYVD-EDKIREGVKRLA 401
DV N + + FT+ +D + E ++RL+
Sbjct: 362 QADVWNHL-VRFTFCKRDDTLDEAIRRLS 389
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.138 0.395
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 159389299
Number of Sequences: 2977
Number of extensions: 7291098
Number of successful extensions: 31823
Number of sequences better than 1.0e-10: 174
Number of HSP's better than 0.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 31387
Number of HSP's gapped (non-prelim): 181
length of query: 410
length of database: 189,106,746
effective HSP length: 57
effective length of query: 353
effective length of database: 154,992,987
effective search space: 54712524411
effective search space used: 54712524411
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)