BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2233 (PAB2233) DE:26S protease regulatory subunit 4
(399 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75207 26s proteinase regulatory chain 4 PAB2233 - Pyrococc... 790 0.0
pir||G71242 probable 26S proteinase regulatory subunit - Pyrococ... 764 0.0
gi|11499558 26S protease regulatory subunit 4 [Archaeoglobus ful... 485 e-136
sp|O26824|PRS1_METTH PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HO... 474 e-132
sp|Q58576|PRS1_METJA PROTEASOME-ACTIVATING NUCLEOTIDASE (PAN) (2... 467 e-131
gb|AAK40609.1| AAA family ATPase [Sulfolobus solfataricus] 430 e-119
pir||F72504 probable 26S proteinase regulatory subunit APE2012 -... 418 e-116
sp|P41836|PRS8_SCHPO 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG (... 372 e-102
gb|AAF22526.1|AF123395_1 (AF123395) 26S proteasome AAA-ATPase su... 370 e-101
gb|AAF27916.1|AF220199_1 (AF220199) 26S proteasome regulatory su... 369 e-101
dbj|BAB17626.1| (AB033537) 26S proteasome regulatory particle tr... 367 e-100
gb|AAC63219.1| (AF043734) Pros45 proteosome subunit homolog [Dro... 366 e-100
pir||A44468 26S proteasome regulatory chain 4 [validated] - human 365 e-100
gi|4506207 proteasome (prosome, macropain) 26S subunit, ATPase, ... 365 e-100
gi|6679501 protease (prosome, macropain) 26S subunit, ATPase 1 [... 365 e-100
pir||T27048 hypothetical protein Y49E10.1 - Caenorhabditis elega... 364 e-100
emb|CAA61864.1| (X89719) put. 26S protease subunit [Sus scrofa] 363 2e-99
sp|O18413|PRS8_DROME 26S PROTEASE REGULATORY SUBUNIT 8 >gi|22454... 363 2e-99
gi|7110703 protease (prosome, macropain) 26S subunit, ATPase 5 [... 363 2e-99
sp|P47210|PRS8_HUMAN 26S PROTEASE REGULATORY SUBUNIT 8 (PROTEASO... 363 3e-99
sp|P48601|PRS4_DROME 26S PROTEASE REGULATORY SUBUNIT 4 (P26S4) >... 362 4e-99
pir||T43799 proteasome protein p45/SUG [imported] - rat (fragmen... 362 4e-99
gb|AAF56205.1| (AE003745) Pros26.4 gene product [Drosophila mela... 362 4e-99
pir||T49402 probable 26S proteinase subunit (SUG1) protein [impo... 361 6e-99
sp|P54814|PRS8_MANSE 26S PROTEASE REGULATORY SUBUNIT 8 (18-56 PR... 361 7e-99
pir||T33633 hypothetical protein F56F11.4 - Caenorhabditis elega... 360 1e-98
sp|Q90732|PRS4_CHICK 26S PROTEASE REGULATORY SUBUNIT 4 (P26S4) >... 360 1e-98
emb|CAC14432.1| (AJ291500) 26S proteasome subunit 4-like protein... 360 2e-98
gb|AAF69154.1|AC007915_6 (AC007915) F27F5.8 [Arabidopsis thaliana] 360 2e-98
gb|AAD24384.1|AC006081_20 (AC006081) 26S proteasome subunit 4 [A... 360 2e-98
gb|AAF22522.1|AF123391_1 (AF123391) 26S proteasome AAA-ATPase su... 359 3e-98
pir||T08959 proteinase homolog F19B15.70 - Arabidopsis thaliana ... 359 3e-98
gi|4506213 proteasome (prosome, macropain) 26S subunit, ATPase, ... 359 4e-98
gb|AAF22524.1|AF123393_1 (AF123393) 26S proteasome AAA-ATPase su... 359 4e-98
sp|P34124|PRS8_DICDI 26S PROTEASE REGULATORY SUBUNIT 8 (TAT-BIND... 358 5e-98
sp|O16368|PRS4_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT 4 ... 358 8e-98
sp|P46466|PRS4_ORYSA 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG (... 357 1e-97
gb|AAF57069.1| (AE003774) CG2241 gene product [Drosophila melano... 357 1e-97
gb|AAF46146.1| (AE003437) Rpt4 gene product [Drosophila melanoga... 356 2e-97
sp|P46470|PRS8_XENLA 26S PROTEASE REGULATORY SUBUNIT 8 (SUG1 HOM... 355 4e-97
dbj|BAB17625.1| (AB033536) 26S proteasome regulatory particle tr... 355 6e-97
sp|Q25544|PRS8_NAEFO 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG (... 354 7e-97
gi|6321390 ATPase; Rpt6p [Saccharomyces cerevisiae] >gi|1709801|... 354 1e-96
gb|AAF08391.1|AF145310_1 (AF145310) 26S proteasome regulatory co... 354 1e-96
prf||1813279A SUG1 gene [Saccharomyces cerevisiae] 354 1e-96
emb|CAA47023.1| (X66400) sug1 [Saccharomyces cerevisiae] >gi|119... 354 1e-96
gb|AAF91246.1|AF227502_1 (AF227502) proteasome regulatory ATPase... 352 5e-96
gi|6320197 (putative) 26S protease subunit; Rpt2p [Saccharomyces... 351 8e-96
gb|AAF08387.1|AF145306_1 (AF145306) 26S proteasome regulatory co... 351 1e-95
gb|AAA97498.1| (L17040) ATPase [Saccharomyces cerevisiae] 351 1e-95
sp|P46507|PRS6_MANSE 26S PROTEASE REGULATORY SUBUNIT 6B (ATPASE ... 350 2e-95
gi|11434084 similar to proteasome (prosome, macropain) 26S subun... 350 2e-95
emb|CAA11285.1| (AJ223384) 26S proteasome regulatory ATPase subu... 349 2e-95
pir||T48743 probable 26S ATP/ubiquitin-dependent proteinase chai... 349 2e-95
sp|Q63570|PRS6_RAT 26S PROTEASE REGULATORY SUBUNIT 6B (TAT-BINDI... 349 4e-95
gi|5729991 proteasome (prosome, macropain) 26S subunit, ATPase, ... 349 4e-95
sp|P43686|PRS6_HUMAN 26S PROTEASE REGULATORY SUBUNIT 6B (TAT-BIN... 348 5e-95
sp|O17071|PRSX_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT S1... 348 5e-95
sp|P46502|PRS6_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT 6B... 348 7e-95
gi|4506215 proteasome (prosome, macropain) 26S subunit, ATPase, ... 348 7e-95
gi|6324833 ATPase; component of the 26S proteasome cap subunit; ... 347 1e-94
gb|AAC32612.1| (AF020736) ATPase homolog [Homo sapiens] 347 2e-94
gb|AAF49987.1| (AE003543) CG7257 gene product [Drosophila melano... 346 2e-94
sp|P54778|PRS6_SOLTU 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG ... 346 3e-94
gb|AAA85134.1| (U43720) Sug2p [Saccharomyces cerevisiae] 346 4e-94
gb|AAB24841.1| Tat binding protein 7, TBP-7=transcriptional acti... 345 5e-94
gb|AAG19042.1| (AE005003) ATP-dependent 26S proteinase regulator... 344 8e-94
gi|7110701 proteasome (prosome, macropain) 26S subunit, ATPase, ... 343 2e-93
gb|AAF35993.1|AC005836_5 (AC005836) 26S Protease Regulatory Subu... 342 3e-93
gb|AAF22523.1|AF123392_1 (AF123392) 26S proteasome AAA-ATPase su... 342 4e-93
gb|AAF91245.1|AF227501_1 (AF227501) proteasome regulatory ATPase... 342 5e-93
pir||S51042 tat-binding protein homolog - malaria parasite (Plas... 341 7e-93
emb|CAB63651.1| (AJ251819) 26S proteasome subunit 8 [Fagus sylva... 341 7e-93
sp|P34123|PRS6_DICDI 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG ... 340 1e-92
dbj|BAB17624.1| (AB033535) 26S proteasome regulatory particle tr... 340 1e-92
gi|4506209 proteasome (prosome, macropain) 26S subunit, ATPase, ... 340 2e-92
sp|P46472|PRS7_XENLA 26S PROTEASE REGULATORY SUBUNIT 7 (MSS1 PRO... 340 2e-92
sp|Q41365|PRS7_SPIOL 26S PROTEASE REGULATORY SUBUNIT 7 (26S PROT... 339 4e-92
gb|AAF54440.1| (AE003684) CG9475 gene product [Drosophila melano... 339 4e-92
gb|AAB33476.1| Tat-binding protein alpha, DdTBP alpha=Tat-bindin... 339 5e-92
gi|6322704 putative ATPase, 26S protease subunit component; Rpt1... 338 6e-92
gb|AAF91244.1|AF227500_1 (AF227500) proteasome regulatory ATPase... 338 6e-92
gb|AAF08388.1|AF145307_1 (AF145307) 26S proteasome regulatory co... 337 1e-91
sp|Q63347|PRS7_RAT 26S PROTEASE REGULATORY SUBUNIT 7 (MSS1 PROTE... 337 1e-91
sp|O64982|PRS7_PRUPE 26S PROTEASE REGULATORY SUBUNIT 7 (26S PROT... 337 1e-91
sp|P46471|PRS7_MOUSE 26S PROTEASE REGULATORY SUBUNIT 7 (MSS1 PRO... 337 2e-91
gb|AAF02852.1|AC009324_1 (AC009324) 26S proteasome ATPase subuni... 337 2e-91
gb|AAG38539.1|AF309805_4 (AF309805) putative 26S protease regula... 337 2e-91
sp|Q18787|PRS7_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT 7 ... 336 3e-91
gb|AAF91248.1|AF227504_1 (AF227504) proteasome regulatory ATPase... 336 3e-91
sp|P36612|PRS4_SCHPO 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG (... 335 5e-91
emb|CAA16915.2| (AL021767) 26s protease regulatory subunit 7 hom... 335 5e-91
pir||T39558 26S proteinase regulatory subunit 7 - fission yeast ... 335 5e-91
gb|AAG20171.1| (AE005094) ATP-dependent 26S proteinase regulator... 334 1e-90
gb|AAF22521.1|AF123390_1 (AF123390) 26S proteasome AAA-ATPase su... 333 2e-90
pir||T41420 26S proteinase regulatory subunit 6b homolog - fissi... 331 1e-89
gb|AAF02853.1|AC009324_2 (AC009324) Putative 26S proteasome ATPa... 331 1e-89
pir||T49507 probable 26S proteasome regulatory particle chain RP... 331 1e-89
sp|P78578|PRS6_ASPNG 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG ... 324 8e-88
gi|11425970 proteasome (prosome, macropain) 26S subunit, ATPase,... 324 1e-87
pir||S39349 MSS1 protein homolog - mouse 323 2e-87
gb|AAF91243.1|AF227499_1 (AF227499) proteasome regulatory ATPase... 322 4e-87
gb|AAB70882.1| (U77918) spermatogenic cell/sperm-associated Tat-... 321 1e-86
gb|AAB88187.1| (AF035309) similar to 26S proteasome subunit p45 ... 321 1e-86
sp|Q63569|PRSA_RAT 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDI... 319 3e-86
gi|11437005 proteasome (prosome, macropain) 26S subunit, ATPase,... 319 3e-86
sp|O42586|PRSB_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BIN... 318 6e-86
gb|AAB24840.1| Tat binding protein 1, TBP-1=transcriptional acti... 317 1e-85
sp|P33298|PRS6_YEAST 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG ... 317 1e-85
gi|6320602 ATPase (AAA family) component of the 26S proteasome c... 317 1e-85
gi|6679503 proteasome (prosome, macropain) 26S subunit, ATPase 3... 317 1e-85
gi|4506211 proteasome (prosome, macropain) 26S subunit, ATPase, ... 317 1e-85
sp|P17980|PRSA_HUMAN 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BIN... 317 1e-85
sp|O23894|PRSA_BRACM 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 316 2e-85
gb|AAF22525.1|AF123394_1 (AF123394) 26S proteasome AAA-ATPase su... 316 4e-85
gb|AAD46145.1| (AF081573) 19S proteasome regulatory complex subu... 314 1e-84
sp|P46465|PRSA_ORYSA 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 314 1e-84
sp|P54776|PRSA_LYCES 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 312 3e-84
sp|O04019|PRSA_ARATH 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 311 8e-84
pir||T33155 hypothetical protein F56H1.4 - Caenorhabditis elegan... 309 3e-83
gi|6324691 26S protease regulatory subunit; Rpt5p [Saccharomyces... 308 9e-83
gb|AAB42248.1| (U88170) Contains similarity to Pfam domain: PF00... 308 9e-83
pir||T44596 26S proteasome regulatory complex chain p50 [importe... 308 9e-83
gb|AAF91247.1|AF227503_1 (AF227503) proteasome regulatory ATPase... 304 1e-81
sp|O14126|PRSA_SCHPO 26S PROTEASE REGULATORY SUBUNIT 6A >gi|7435... 298 7e-80
sp|O42587|PRSA_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BIN... 296 2e-79
gb|AAD24194.1|AF134402_1 (AF134402) Tat-binding protein-1 [Droso... 294 1e-78
pir||H71114 probable cell division control protein (transitional... 267 1e-70
gi|11499681 cell division control protein 48, AAA family (cdc48-... 259 5e-68
sp|O67077|FTSH_AQUAE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 256 4e-67
pir||A69086 cell division control protein Cdc48 - Methanobacteri... 250 1e-65
pir||E72358 cell division protein FtsH - Thermotoga maritima (st... 243 3e-63
gb|AAG20864.1| (AE005154) cell division cycle protein; Cdc48d [H... 239 5e-62
emb|CAB51029.1| (AJ243808) metalloprotease FtsH [Bradyrhizobium ... 238 6e-62
pir||F72009 cell division protein FtsH, probable CP0857 [importe... 238 1e-61
pir||T48355 transitional endoplasmic reticulum ATPase - Arabidop... 237 2e-61
gi|6320077 microsomal ATPase; Cdc48p [Saccharomyces cerevisiae] ... 236 3e-61
pir||F81725 cell division protein FtsH, probable TC0229 [importe... 235 7e-61
pir||D71463 probable ATP-dependent zinc proteinase - Chlamydia t... 235 1e-60
pir||T36330 cell division protein ftsH2 - Streptomyces coelicolo... 235 1e-60
gi|11467752 hypothetical chloroplast RF25 [Guillardia theta] >gi... 234 1e-60
gi|11465793 hypothetical chloroplast ORF 25. [Porphyra purpurea]... 234 2e-60
sp|P28691|FTSH_ECOLI CELL DIVISION PROTEIN FTSH >gi|421034|pir||... 233 3e-60
gb|AAA97508.1| (U01376) ATP-binding protein [Escherichia coli] 233 3e-60
gb|AAC32257.1| (AF037269) cell division protein [Mycobacterium s... 233 3e-60
gi|10946660 spermatogenesis associated factor [Mus musculus] >gi... 233 4e-60
pir||G81315 membrane bound zinc metallopeptidase (EC 3.4.24.-) C... 233 4e-60
sp|P71408|FTSH_HELPY CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 232 5e-60
pir||D70198 cell division protein (ftsH) homolog - Lyme disease ... 232 5e-60
sp|O32617|FTSH_HELFE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1127... 231 8e-60
sp|Q9ZM66|FTSH_HELPJ CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 231 8e-60
pir||E81948 probable ATP-dependent zinc metallopeptidase (EC 3.4... 231 1e-59
pir||T31466 cell-division protein homolog ftsH - Heliobacillus m... 231 1e-59
dbj|BAB13085.1| (AP001119) cell division protein ftsh [Buchnera ... 231 1e-59
sp|Q55700|FTH1_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|74... 230 2e-59
pir||E81157 cell division protein FtsH NMB0798 [imported] - Neis... 229 3e-59
pir||F83053 cell division protein FtsH PA4751 [imported] - Pseud... 229 5e-59
sp|P96942|FTSH_MYCTU CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7478... 228 7e-59
sp|P94304|FTSH_BACFI CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1813... 228 9e-59
gb|AAB66377.1| (U97567) FtsH [Helicobacter pylori] 228 9e-59
sp|P37476|FTSH_BACSU CELL DIVISION PROTEIN FTSH HOMOLOG >gi|2126... 228 1e-58
sp|P71377|FTH1_HAEIN CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|15... 228 1e-58
sp|P72991|FTH4_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 4 >gi|74... 227 2e-58
gi|5802970 AFG3-like 2; ATPase family gene 3-like 2; ATPase fami... 227 2e-58
sp|P73437|FTH3_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 3 >gi|74... 227 2e-58
sp|O83746|FTSH_TREPA CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 227 2e-58
pir||D75502 cell division protein FtsH - Deinococcus radiodurans... 227 2e-58
sp|P73179|FTH2_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 2 >gi|74... 226 4e-58
gi|11431428 similar to proteasome (prosome, macropain) 26S subun... 226 4e-58
pir||T23322 hypothetical protein K04G2.3 - Caenorhabditis elegan... 226 5e-58
pir||E82299 cell division protein FtsH VC0637 [imported] - Vibri... 225 6e-58
dbj|BAA88165.1| (AB024399) FtsH (FtsHcp) [Cyanidioschyzon merolae] 225 8e-58
pir||T11652 probable transitional endoplasmic reticulum ATPase -... 224 1e-57
emb|CAA18796.1| (AL023093) cell division protein FtsH [Mycobacte... 224 1e-57
dbj|BAB03804.1| (AP001507) cell-division protein (ATP-dependent ... 224 2e-57
gb|AAC16243.2| (AF061748) cell division protein FtsH [Streptococ... 223 2e-57
sp|O69076|FTSH_STRPN CELL DIVISION PROTEIN FTSH HOMOLOG 223 2e-57
gb|AAC44563.1| (U59452) HpFtsH [Helicobacter pylori] 223 3e-57
pir||G75582 cell division protein FtsH - Deinococcus radiodurans... 222 4e-57
sp|P46469|FTSH_LACLA CELL DIVISION PROTEIN FTSH HOMOLOG >gi|2126... 217 1e-55
pir||B81376 probable membrane bound ATPase (EC 3.4.24.-) Cj1005c... 214 1e-54
pir||T34772 cell division protein ftsH - Streptomyces coelicolor... 213 3e-54
sp|P47695|FTSH_MYCGE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1361... 213 4e-54
pir||T02738 hypothetical protein T9I4.16 - Arabidopsis thaliana ... 209 4e-53
pir||D82934 ATP-dependent zinc metallopeptidase, cell division p... 209 5e-53
dbj|BAB08420.1| (AB025622) cell division protein FtsH protease-l... 207 2e-52
gb|AAF60660.1| (AC024791) contains similarity to Pfam families P... 206 5e-52
gi|7305635 YME1-like 1 (S. cerevisiae); ATP-dependent metallopro... 203 3e-51
gb|AAF79577.1|AC022464_35 (AC022464) F22G5.10 [Arabidopsis thali... 203 4e-51
emb|CAC05251.1| (AL391604) putative mitochondrial respiratory ch... 203 4e-51
pir||T41073 26s protease regulatory subunit S10b - fission yeast... 202 5e-51
gi|6325281 Mitochondrial member of the CDC48/PAS1/SEC18 family o... 202 7e-51
emb|CAA56954.1| (X81067) probable mitochondrial protein; nearly ... 202 7e-51
dbj|BAA03839.1| (D16332) OSD1 gene product [Saccharomyces cerevi... 202 7e-51
gb|AAD20962.1| (AF070656) FtsH homolog [Homo sapiens] 201 1e-50
gi|7657689 YME1 (S.cerevisiae)-like 1 [Homo sapiens] >gi|5689742... 201 1e-50
emb|CAB99462.1| (AJ295618) putative ATPases [Homo sapiens] 201 1e-50
emb|CAA54091.1| (X76643) Afg3p [Saccharomyces cerevisiae] 200 2e-50
gb|AAK42565.1| AAA family ATPase [Sulfolobus solfataricus] 199 3e-50
emb|CAA56963.1| (X81072) YTA7 [Saccharomyces cerevisiae] 199 6e-50
gi|6321709 26S proteasome ATPase; Yta7p [Saccharomyces cerevisia... 199 6e-50
pir||A70632 hypothetical protein Rv0435c - Mycobacterium tubercu... 199 6e-50
gi|4507173 paraplegin [Homo sapiens] >gi|3273089|emb|CAA76314.1|... 198 8e-50
gb|AAD28099.1| (AF080525) paraplegin [Homo sapiens] 198 8e-50
gi|6320854 ATP-dependent metalloprotease; Afg3p [Saccharomyces c... 198 1e-49
pir||S52928 XSUG1 protein - African clawed frog 198 1e-49
gi|6322994 Yll034cp [Saccharomyces cerevisiae] >gi|2492526|sp|Q0... 198 1e-49
gb|AAF47769.1| (AE003478) CG12010 gene product [Drosophila melan... 187 3e-46
sp|Q13608|PEX6_HUMAN PEROXISOME ASSEMBLY FACTOR-2 (PAF-2) (PEROX... 177 2e-43
gi|4505729 peroxisomal biogenesis factor 6; Peroxisomal biogenes... 177 2e-43
gi|11417640 peroxisomal biogenesis factor 6 [Homo sapiens] 177 2e-43
dbj|BAB00559.1| (AP001299) contains similarity to 26S proteasome... 175 8e-43
pir||E64486 ATP-dependent 26S proteosome regulatory subunit 8 ho... 173 3e-42
sp|Q58889|PRS2_METJA PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HO... 173 3e-42
pir||T03904 hypothetical protein F39G3.7 - Caenorhabditis elegan... 171 2e-41
gi|6325183 Yta6p [Saccharomyces cerevisiae] >gi|2133218|pir||S61... 167 2e-40
pir||T50122 vesicular transport protein sec18 homolog [imported]... 161 2e-38
gb|AAC46844.1| (U28836) N-ethylmaleimide sensitive fusion protei... 155 8e-37
sp|P54351|NSF2_DROME VESICULAR-FUSION PROTEIN NSF2 (N-ETHYLMALEI... 155 8e-37
gb|AAF54995.1| (AE003702) Nsf2 gene product [Drosophila melanoga... 155 8e-37
sp|P46461|NSF1_DROME VESICULAR-FUSION PROTEIN NSF1 (N-ETHYLMALEI... 153 4e-36
gb|AAF48244.1| (AE003492) comt gene product [Drosophila melanoga... 153 4e-36
pir||D75493 cell division cycle protein 48-related protein - Dei... 152 7e-36
gb|AAF18300.1|AF118384_1 (AF118384) N-ethylmaleimide sensitive f... 152 9e-36
pir||S37606 SEC18 protein - yeast (Candida albicans) 147 2e-34
sp|P34732|SC18_CANAL VESICULAR-FUSION PROTEIN SEC18 >gi|578124|e... 147 2e-34
gb|AAF51127.1| (AE003580) CG3326 gene product [Drosophila melano... 147 2e-34
sp|P54815|MSP1_CAEEL MSP1 PROTEIN HOMOLOG >gi|7505276|pir||T2331... 142 6e-33
gi|6320887 member of the AAA ATPase family of proteins; Sap1p [S... 140 3e-32
pir||T18421 hypothetical protein C0140c - malaria parasite (Plas... 139 5e-32
gb|AAC48226.1| (AF006826) N-ethylmaleimide-sensitive fusion prot... 138 1e-31
gi|11466408 hypothetical chloroplast RF2 [Mesostigma viride] >gi... 133 3e-30
gb|AAG28839.1| (U59880) filamentation temperature sensitive H-li... 117 2e-25
pir||JQ1233 hypothetical 41.8K protein - Synechocystis sp >gi|21... 106 5e-22
pir||S76117 hypothetical protein slr0374 - Synechocystis sp. (st... 106 5e-22
pir||S74396 hypothetical protein slr0480 - Synechocystis sp. (st... 103 4e-21
gb|AAB05472.1| (U59625) unknown [Helicobacter pylori] 88 2e-16
>pir||H75207 26s proteinase regulatory chain 4 PAB2233 - Pyrococcus abyssi
(strain Orsay) >gi|5457620|emb|CAB49111.1| (AJ248283)
26S protease regulatory subunit 4 [Pyrococcus abyssi]
Length = 399
Score = 790 bits (2017), Expect = 0.0
Identities = 399/399 (100%), Positives = 399/399 (100%)
Query: 1 MNIMSGDEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP 60
MNIMSGDEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP
Sbjct: 1 MNIMSGDEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP 60
Query: 61 PAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS 120
PAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS
Sbjct: 61 PAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS 120
Query: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY
Sbjct: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
Query: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID
Sbjct: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
Query: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG
Sbjct: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
Query: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFA 360
RFDRLIEVPLPDFEGRLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFA
Sbjct: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFA 360
Query: 361 IRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEIIYG 399
IRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEIIYG
Sbjct: 361 IRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEIIYG 399
>pir||G71242 probable 26S proteinase regulatory subunit - Pyrococcus horikoshii
>gi|3256587|dbj|BAA29270.1| (AP000001) 399aa long
hypothetical 26S protease regulatory subunit [Pyrococcus
horikoshii]
Length = 399
Score = 764 bits (1952), Expect = 0.0
Identities = 382/399 (95%), Positives = 393/399 (97%)
Query: 1 MNIMSGDEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP 60
M++MSGDEVQF +YDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP
Sbjct: 1 MSVMSGDEVQFQGDYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP 60
Query: 61 PAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS 120
PAFAGTVIEVLD+DRAIVQNYNGPRFVVRIAPWI+R KLRPG RVALDQRTMA++E+LP+
Sbjct: 61 PAFAGTVIEVLDEDRAIVQNYNGPRFVVRIAPWIDRKKLRPGTRVALDQRTMAVVEILPT 120
Query: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY
Sbjct: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
Query: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID
Sbjct: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
Query: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG
Sbjct: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
Query: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFA 360
RFDRLIEVPLPDFEGRLEILKVHTRRMKLK VDLR IAE+TEGASGADLKAIATEAGMFA
Sbjct: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKLKGVDLRAIAEMTEGASGADLKAIATEAGMFA 360
Query: 361 IRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEIIYG 399
IRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHE+IYG
Sbjct: 361 IRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEVIYG 399
>gi|11499558 26S protease regulatory subunit 4 [Archaeoglobus fulgidus]
>gi|3122632|sp|O28303|PRS1_ARCFU PUTATIVE 26S PROTEASE
REGULATORY SUBUNIT HOMOLOG AF1976
>gi|7435736|pir||G69496 ATP-dependent 26S proteinase
regulatory subunit 4 homolog - Archaeoglobus fulgidus
>gi|2648566|gb|AAB89280.1| (AE000967) 26S protease
regulatory subunit 4 [Archaeoglobus fulgidus]
Length = 398
Score = 485 bits (1235), Expect = e-136
Identities = 238/367 (64%), Positives = 302/367 (81%), Gaps = 2/367 (0%)
Query: 16 DDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDR 75
+DY L+ R+LE + + +E+++ R ERE+ RLRSE+ RLR PP G V ++L+D R
Sbjct: 18 EDYYK-LRELYRRLEDEKKFIESERIRYEREVRRLRSEVERLRSPPLLVGVVSDILEDGR 76
Query: 76 AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERP 135
+V++ GP+FVV + +I ++L+PGARVAL+Q+T+AI+ +LP+SKDP V GFEV E+P
Sbjct: 77 VVVKSSTGPKFVVNTSQYINEEELKPGARVALNQQTLAIVNVLPTSKDPMVYGFEVEEKP 136
Query: 136 NVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALA 195
V+Y DIGGL Q++E+REA+ELPL PELF EVGI+PPKGVLLYGPPG GKTL+AKA+A
Sbjct: 137 EVSYEDIGGLDVQIEEIREAVELPLLKPELFAEVGIEPPKGVLLYGPPGTGKTLLAKAVA 196
Query: 196 HEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTG 255
++ ATFIRVVGSE V+KYIGEGARLV E+F+LAKEKAP+IIFIDE+DAI A+R + T
Sbjct: 197 NQTRATFIRVVGSEFVQKYIGEGARLVREVFQLAKEKAPSIIFIDELDAIAARRTNSDTS 256
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
G+REV RT+MQLLAE+DGFDPRG+VKVI ATNR DILDPA+LRPGRFDR+IEVPLP FEG
Sbjct: 257 GDREVQRTMMQLLAELDGFDPRGDVKVIGATNRIDILDPAILRPGRFDRIIEVPLPTFEG 316
Query: 316 RLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFL 374
R++I K+HTR+MKL ++VD + +A ITEGASGAD+KAI TEAGMFAIRE R VT DF
Sbjct: 317 RIQIFKIHTRKMKLAEDVDFKELARITEGASGADIKAICTEAGMFAIREERAKVTMLDFT 376
Query: 375 KAVDKVL 381
KA++KVL
Sbjct: 377 KAIEKVL 383
>sp|O26824|PRS1_METTH PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HOMOLOG MTH728
>gi|7435737|pir||C69197 ATP-dependent 26S proteinase
regulatory subunit 4 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621817|gb|AAB85233.1| (AE000852) ATP-dependent 26S
protease regulatory subunit 4 [Methanobacterium
thermoautotrophicum]
Length = 410
Score = 474 bits (1206), Expect = e-132
Identities = 230/363 (63%), Positives = 294/363 (80%), Gaps = 1/363 (0%)
Query: 25 RIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGP 84
+IR+LE ++E ++ RL+RE+ LR E+ R R PP TV EVLDD R V++ GP
Sbjct: 36 KIRKLEKDKLLIENERTRLDREVKSLRGEIERFRTPPLVIATVTEVLDDHRVAVKSTTGP 95
Query: 85 RFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGG 144
FV+ + +I+R +L PGARVAL+Q+T +I+++LPS KDP V G EV E+P+V+Y IGG
Sbjct: 96 HFVINYSRFIDRKQLEPGARVALNQQTFSIVDVLPSEKDPVVTGMEVEEKPDVSYEQIGG 155
Query: 145 LKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIR 204
L++Q++E++E +ELPLK PELFE++GI+PPKGVLLYGPPG GKTL+AKA+AHE NATFI+
Sbjct: 156 LEEQVREVKETVELPLKKPELFEKIGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIK 215
Query: 205 VVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTL 264
+V SE VRKYIGEGARLV +FELAKEK+P+IIFIDEIDA+ AKR+ +T G+REV RTL
Sbjct: 216 IVASEFVRKYIGEGARLVRGVFELAKEKSPSIIFIDEIDAVAAKRLKSSTSGDREVQRTL 275
Query: 265 MQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHT 324
MQLLAE+DGF+ RGNV ++AATNRPDILDPALLRPGRFDR IEVPLP+ +GR EILK+HT
Sbjct: 276 MQLLAELDGFESRGNVGIVAATNRPDILDPALLRPGRFDRFIEVPLPNEDGRREILKIHT 335
Query: 325 RRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGN 383
M L + VD+ ++A IT+GASGADLKAI TEAGMFAIR+ R VT DF+ AVDK++G
Sbjct: 336 SGMALAEEVDIELLARITDGASGADLKAICTEAGMFAIRDERDEVTMADFMDAVDKIMGV 395
Query: 384 ERK 386
E++
Sbjct: 396 EKE 398
>sp|Q58576|PRS1_METJA PROTEASOME-ACTIVATING NUCLEOTIDASE (PAN) (26S PROTEASE REGULATORY
SUBUNIT HOMOLOG) >gi|2127779|pir||G64446 ATP-dependent
26S proteosome regulatory subunit 4 homolog -
Methanococcus jannaschii >gi|1591803|gb|AAB99179.1|
(U67559) proteasome regulatory AAA-ATPase [Methanococcus
jannaschii]
Length = 430
Score = 467 bits (1190), Expect = e-131
Identities = 230/381 (60%), Positives = 301/381 (78%), Gaps = 1/381 (0%)
Query: 19 ITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIV 78
I L+ RI +LEL+ + LE + +L +E LR E+ R+R PP GTV++ + + + +V
Sbjct: 49 IAELESRILKLELEKKELERENLQLMKENEILRRELDRMRVPPLIVGTVVDKVGERKVVV 108
Query: 79 QNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVT 138
++ GP F+V ++ ++ D L PG RV L+Q+T+ ++++LP +KD EV ERPNV
Sbjct: 109 KSSTGPSFLVNVSHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAMEVDERPNVR 168
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
Y DIGGL+KQ+QE+RE +ELPLKHPELFE+VGI+PPKG+LLYGPPG GKTL+AKA+A E
Sbjct: 169 YEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATET 228
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
NATFIRVVGSELV+K+IGEGA LV ++F+LAKEKAP+IIFIDEIDAI AKR D TGG+R
Sbjct: 229 NATFIRVVGSELVKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDR 288
Query: 259 EVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
EV RTLMQLLAEMDGFD RG+VK+I ATNRPDILDPA+LRPGRFDR+IEVP PD +GRLE
Sbjct: 289 EVQRTLMQLLAEMDGFDARGDVKIIGATNRPDILDPAILRPGRFDRIIEVPAPDEKGRLE 348
Query: 319 ILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAV 377
ILK+HTR+M L ++V+L IA++TEG GA+LKAI TEAGM AIRE R YVT +DF KAV
Sbjct: 349 ILKIHTRKMNLAEDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVTMDDFRKAV 408
Query: 378 DKVLGNERKLLQQITSHEIIY 398
+K++ ++ +++ +++Y
Sbjct: 409 EKIMEKKKVKVKEPAHLDVLY 429
>gb|AAK40609.1| AAA family ATPase [Sulfolobus solfataricus]
Length = 393
Score = 430 bits (1094), Expect = e-119
Identities = 205/363 (56%), Positives = 281/363 (76%), Gaps = 1/363 (0%)
Query: 26 IRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPR 85
+R LE +++ L+ + E L +EL+ ++EM ++ PP V++VL D R +V++ +GP
Sbjct: 20 VRLLEEKIKSLQIEIENLRKELNYYKAEMEKMLSPPLIEAVVLDVLPDGRVLVRSSSGPN 79
Query: 86 FVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGL 145
VV IA I++ ++PG VAL+QR I+E+LP +DP V E+IERPNVTY++IGGL
Sbjct: 80 LVVNIASHIDQKLIKPGISVALNQRGSTILEVLPQKEDPIVKTMEIIERPNVTYSEIGGL 139
Query: 146 KKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRV 205
++Q++ELRE +ELPLK+PE+F E+G++PPKGVLLYGPPG GKT++AKA+A E NA FI V
Sbjct: 140 EEQIRELREVVELPLKNPEIFREIGVEPPKGVLLYGPPGTGKTMLAKAVATESNAVFIHV 199
Query: 206 VGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLM 265
V SE +K++GEGAR+V ELFE+AK KAP+IIFIDEIDAIGAKR+D T GERE+ RTLM
Sbjct: 200 VASEFAQKFVGEGARIVRELFEMAKRKAPSIIFIDEIDAIGAKRIDIGTSGEREIQRTLM 259
Query: 266 QLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTR 325
QLLAE+DGFDP NVK+IAATNR DILDPALLRPGRFDR+IEVPLPDF+GR EI ++ +
Sbjct: 260 QLLAELDGFDPLDNVKIIAATNRIDILDPALLRPGRFDRIIEVPLPDFKGRTEIFNIYLK 319
Query: 326 RMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNE 384
+MK++ N++L +++++TEG SGAD+K + EA AIR+ R VT D ++A++K+
Sbjct: 320 KMKIEDNINLELLSQLTEGFSGADIKNVCVEAAYMAIRDGRNKVTMNDLVEAINKINVKR 379
Query: 385 RKL 387
K+
Sbjct: 380 NKM 382
>pir||F72504 probable 26S proteinase regulatory subunit APE2012 - Aeropyrum
pernix (strain K1) >gi|5105710|dbj|BAA81022.1|
(AP000063) 409aa long hypothetical 26S protease
regulatory subunit [Aeropyrum pernix]
Length = 409
Score = 418 bits (1063), Expect = e-116
Identities = 207/356 (58%), Positives = 272/356 (76%), Gaps = 1/356 (0%)
Query: 26 IRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPR 85
IR L+ +VR L +K L++EL ++E+++L PP V+EV+DD+R +V++ GP
Sbjct: 25 IRILKDKVRSLTKEKISLQKELEYYKNEITKLLSPPYIEAVVLEVIDDNRVVVKSSTGPN 84
Query: 86 FVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGL 145
+V +A ++ L+PGA VAL+ R I+++LP DP V EV ERP V + D+GGL
Sbjct: 85 LIVNVAAGVDARSLKPGAIVALNNRGSTIVDVLPGRYDPLVKAMEVEERPKVFFKDVGGL 144
Query: 146 KKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRV 205
++Q++E+ EA+ LP+K+P LF E+GIDPPKGVLL+GPPG GKTL+AKA+A E ATFIRV
Sbjct: 145 EEQIREIYEAVVLPIKNPHLFRELGIDPPKGVLLHGPPGTGKTLLAKAVAGETEATFIRV 204
Query: 206 VGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLM 265
VGSELV K+IGEGARLV E+F LA+EKAP+I+FIDEIDAI +KR+D T G+REV RT++
Sbjct: 205 VGSELVNKFIGEGARLVREIFRLAREKAPSILFIDEIDAIASKRVDIGTSGDREVQRTML 264
Query: 266 QLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTR 325
QLLAE+DGFDP NVKVIAATNR D++DPA+LRPGRFDR+IEVPLP GRLEIL +HTR
Sbjct: 265 QLLAELDGFDPLDNVKVIAATNRLDLIDPAVLRPGRFDRIIEVPLPSLRGRLEILGIHTR 324
Query: 326 RMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
+ K+ +VDL IA++TEG SGADLKA+ EAG AIR +T +D +KAV+KV
Sbjct: 325 KAKMAPDVDLEAIAKLTEGFSGADLKAVVVEAGYNAIRRGSRVITMDDMIKAVEKV 380
>sp|P41836|PRS8_SCHPO 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG (LET1 PROTEIN)
>gi|626074|pir||S45176 26S proteinase regulatory subunit
8 homolog - fission yeast (Schizosaccharomyces pombe)
>gi|406051|gb|AAA61615.1| (U02280) Let1
[Schizosaccharomyces pombe] >gi|4106689|emb|CAA22628.1|
(AL035065) 26s protease regulatory subunit 8 homolog
[Schizosaccharomyces pombe]
Length = 403
Score = 372 bits (944), Expect = e-102
Identities = 195/388 (50%), Positives = 273/388 (70%), Gaps = 12/388 (3%)
Query: 3 IMSGDEVQFHENYDDYITYLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMS 55
++ + +Q +EN Y T ++I+ EL + R LEA + L + LR E+
Sbjct: 4 VLKTNVLQSNENIVQYYT---QKIQDAELAILQKTQNLRRLEAQRNGLNARVRLLREEIQ 60
Query: 56 RLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAII 115
L++P ++ G VI+ + ++ +V+ + ++VV I+P I+ +++P RVAL + +I
Sbjct: 61 LLQEPGSYVGEVIKTMGKNKVLVKVHPEGKYVVDISPDIDIKEIKPNIRVALRNDSYQLI 120
Query: 116 ELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPK 175
++LP+ DP V V + P+ TY +GGL+KQ++E++E IELP+KHPELFE +GI PK
Sbjct: 121 KILPNKVDPLVSLMMVEKIPDSTYEMVGGLEKQIKEIKEVIELPVKHPELFESLGIPQPK 180
Query: 176 GVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPT 235
G+LLYGPPG GKTL+A+A+AH + FIRV GSELV+KYIGEG+R+V ELF +A+E AP+
Sbjct: 181 GILLYGPPGTGKTLLARAVAHHTDCKFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPS 240
Query: 236 IIFIDEIDAIGAKRMDETTG-GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDP 294
IIF+DEID+IG+ R D + G G+ EV RT+++LL ++DGF+ N+KVI ATNR DILDP
Sbjct: 241 IIFMDEIDSIGSSRSDSSGGSGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDP 300
Query: 295 ALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIA 353
ALLRPGR DR IE P P E R EIL++H+R M L + +DL+ IAE GASGA+LK +
Sbjct: 301 ALLRPGRIDRKIEFPPPSAEARAEILRIHSRSMNLTRGIDLKSIAEKMNGASGAELKGVC 360
Query: 354 TEAGMFAIRERRTYVTQEDFLKAVDKVL 381
TEAGMFA+RERR +VTQEDF AV KVL
Sbjct: 361 TEAGMFALRERRVHVTQEDFELAVAKVL 388
>gb|AAF22526.1|AF123395_1 (AF123395) 26S proteasome AAA-ATPase subunit RPT6a [Arabidopsis
thaliana]
Length = 405
Score = 370 bits (941), Expect = e-101
Identities = 191/369 (51%), Positives = 266/369 (71%), Gaps = 2/369 (0%)
Query: 15 YDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDD 74
Y +I L+R++RQ + LEA + L + LR E+ L++P ++ G V++V+ +
Sbjct: 22 YLQHIHELQRQLRQKTNNLNRLEAQRNELNSRVRMLREELQLLQEPGSYVGEVVKVMGKN 81
Query: 75 RAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIER 134
+ +V+ + ++VV I I+ K+ P RVAL + + +LPS DP V +V +
Sbjct: 82 KVLVKVHPEGKYVVDIDKSIDITKITPSTRVALRNDSYVLHLVLPSKVDPLVNLMKVEKV 141
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P+ TY+ IGGL +Q++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A+
Sbjct: 142 PDSTYDMIGGLDQQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAV 201
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
AH + TFIRV GSELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ RM+ +
Sbjct: 202 AHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGS 261
Query: 255 G-GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
G G+ EV RT+++LL ++DGF+ +KV+ ATNR DILD ALLRPGR DR IE P P+
Sbjct: 262 GNGDSEVQRTMLELLNQLDGFEASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPNE 321
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
E R +ILK+H+R+M L + +DL+ IAE GASGA+LKA+ TEAGMFA+RERR +VTQED
Sbjct: 322 ESRFDILKIHSRKMNLMRGIDLKKIAEKMNGASGAELKAVCTEAGMFALRERRVHVTQED 381
Query: 373 FLKAVDKVL 381
F AV KV+
Sbjct: 382 FEMAVAKVM 390
>gb|AAF27916.1|AF220199_1 (AF220199) 26S proteasome regulatory subunit 8 [Pinus taeda]
Length = 433
Score = 369 bits (938), Expect = e-101
Identities = 193/373 (51%), Positives = 265/373 (70%), Gaps = 9/373 (2%)
Query: 21 YLKRRIRQLELQVRM-------LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y + I L+LQVR LEA + L ++ LR E+ L++P ++ G V++V+
Sbjct: 49 YYLQHIHDLQLQVRQKTHNLNRLEAQRNDLNSKVRALREELQLLQEPGSYVGEVVKVMGK 108
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ + ++VV + I+ K+ P RVAL + + +LPS DP V +V +
Sbjct: 109 SKVLVKVHPEGKYVVDVDKNIDITKITPSTRVALRNDSYVLHLILPSKVDPLVNLMKVEK 168
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY+ IGGL +Q++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 169 VPDSTYDMIGGLDQQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARA 228
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + TFIRV GSELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ RM+
Sbjct: 229 VAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESG 288
Query: 254 TG-GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
TG G+ EV RT+++LL ++DGF+ +KV+ ATNR DILD ALLRPGR DR IE P P+
Sbjct: 289 TGNGDSEVQRTMLELLNQLDGFEASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPN 348
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
E R +ILK+H+R+M L + +DL+ IAE GASGA+LKA+ TEAGMFA+RERR +VTQE
Sbjct: 349 EESRFDILKIHSRKMNLMRGIDLKKIAEKMSGASGAELKAVCTEAGMFALRERRVHVTQE 408
Query: 372 DFLKAVDKVLGNE 384
DF AV KV+ E
Sbjct: 409 DFEMAVAKVMKKE 421
>dbj|BAB17626.1| (AB033537) 26S proteasome regulatory particle triple-A ATPase
subunit6 [Oryza sativa]
Length = 424
Score = 367 bits (933), Expect = e-100
Identities = 191/369 (51%), Positives = 264/369 (70%), Gaps = 2/369 (0%)
Query: 15 YDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDD 74
Y +I L+ +IRQ + LEA + L + LR E+ L++P ++ G V++V+
Sbjct: 41 YLQHIHDLQLQIRQKTHNLNRLEAQRNDLNSRVRMLREELQLLQEPGSYVGEVVKVMGKS 100
Query: 75 RAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIER 134
+ +V+ + ++VV I I+ K+ P RVAL + + +LPS DP V +V +
Sbjct: 101 KVLVKVHPEGKYVVDIDKSIDITKITPSTRVALRNDSYMLHLILPSKVDPLVNLMKVEKV 160
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P+ TY+ IGGL +Q++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A+
Sbjct: 161 PDSTYDMIGGLDQQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAV 220
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
AH + TFIRV GSELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ RM+ T
Sbjct: 221 AHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGT 280
Query: 255 G-GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
G G+ EV RT+++LL ++DGF+ +KV+ ATNR DILD ALLRPGR DR IE P P+
Sbjct: 281 GNGDSEVQRTMLELLNQLDGFEASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPNE 340
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
+ R +ILK+H+R+M L + +DL+ IAE GASGA+LKA+ TEAGMFA+RERR +VTQED
Sbjct: 341 DSRFDILKIHSRKMNLMRGIDLKKIAEKMNGASGAELKAVCTEAGMFALRERRVHVTQED 400
Query: 373 FLKAVDKVL 381
F AV KV+
Sbjct: 401 FEMAVAKVM 409
>gb|AAC63219.1| (AF043734) Pros45 proteosome subunit homolog [Drosophila
melanogaster] >gi|7295522|gb|AAF50835.1| (AE003568)
Pros45 gene product [Drosophila melanogaster]
Length = 405
Score = 366 bits (930), Expect = e-100
Identities = 187/382 (48%), Positives = 272/382 (70%), Gaps = 9/382 (2%)
Query: 8 EVQFHENYDDYITYLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQP 60
E +H+ + + +Y ++I +L+L V R L+A + L ++ LR E+ L++
Sbjct: 10 ESAYHKG-EGFRSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQ 68
Query: 61 PAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS 120
++ G V++ +D + +V+ + +FVV + I+ + + P RVAL + + ++LP+
Sbjct: 69 GSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPN 128
Query: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
DP V V + P+ TY +GGL KQ++E++E IELP+KHPELF+ +GI PKGVLLY
Sbjct: 129 KVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLY 188
Query: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
GPPG GKTL+A+A+AH TFIRV GSELV+K+IGEG+R+V ELF +A+E AP+IIF+D
Sbjct: 189 GPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMD 248
Query: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
EID+IG+ R++ +GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILDPALLRPG
Sbjct: 249 EIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPG 308
Query: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMF 359
R DR IE P P+ E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+
Sbjct: 309 RIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMY 368
Query: 360 AIRERRTYVTQEDFLKAVDKVL 381
A+RERR +VTQEDF AV KV+
Sbjct: 369 ALRERRVHVTQEDFEMAVAKVM 390
>pir||A44468 26S proteasome regulatory chain 4 [validated] - human
Length = 440
Score = 365 bits (926), Expect = e-100
Identities = 191/370 (51%), Positives = 257/370 (68%), Gaps = 9/370 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ + IR E Q++ LE E+ E E RS++ LR P GT+ E++D
Sbjct: 66 ERIKDYLLMEEEFIRNQE-QMKPLE---EKQEEE----RSKVDDLRGTPMSVGTLEEIID 117
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D+ AIV G V I ++++D L PG V L+ + A+I +L DP V +V
Sbjct: 118 DNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVE 177
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY DIGGL Q+QE++E++ELPL HPE +EE+GI PPKGV+LYGPPG GKTL+AK
Sbjct: 178 KAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A++ +ATF+RVVGSEL++KY+G+G +LV ELF +A+E AP+I+FIDEIDAIG KR D
Sbjct: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDS 297
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+GGERE+ RT+++LL ++DGFD RG+VKVI ATNR + LDPAL+RPGR DR IE PLPD
Sbjct: 298 NSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 357
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ + I ++HT RM L +V L + + SGAD+KAI TEAG+ A+RERR VT E
Sbjct: 358 EKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE 417
Query: 372 DFLKAVDKVL 381
DF K+ + VL
Sbjct: 418 DFKKSKENVL 427
>gi|4506207 proteasome (prosome, macropain) 26S subunit, ATPase, 1; Proteasome
26S subunit, ATPase, 1 [Homo sapiens]
>gi|1172634|sp|Q03527|PRS4_HUMAN 26S PROTEASE REGULATORY
SUBUNIT 4 (P26S4) >gi|403456|gb|AAA35484.1| (L02426) 26S
protease (S4) regulatory subunit [Homo sapiens]
Length = 440
Score = 365 bits (926), Expect = e-100
Identities = 191/370 (51%), Positives = 257/370 (68%), Gaps = 9/370 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ + IR E Q++ LE E+ E E RS++ LR P GT+ E++D
Sbjct: 66 ERIKDYLLMEEEFIRNQE-QMKPLE---EKQEEE----RSKVDDLRGTPMSVGTLEEIID 117
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D+ AIV G V I ++++D L PG V L+ + A+I +L DP V +V
Sbjct: 118 DNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVE 177
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY DIGGL Q+QE++E++ELPL HPE +EE+GI PPKGV+LYGPPG GKTL+AK
Sbjct: 178 KAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A++ +ATF+RVVGSEL++KY+G+G +LV ELF +A+E AP+I+FIDEIDAIG KR D
Sbjct: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDS 297
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+GGERE+ RT+++LL ++DGFD RG+VKVI ATNR + LDPAL+RPGR DR IE PLPD
Sbjct: 298 NSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 357
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ + I ++HT RM L +V L + + SGAD+KAI TEAG+ A+RERR VT E
Sbjct: 358 EKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE 417
Query: 372 DFLKAVDKVL 381
DF K+ + VL
Sbjct: 418 DFKKSKENVL 427
>gi|6679501 protease (prosome, macropain) 26S subunit, ATPase 1 [Mus musculus]
>gi|11434737|ref|XP_007386.1| similar to proteasome
(prosome, macropain) 26S subunit, ATPase, 1 (H. sapiens)
[Homo sapiens] >gi|1346811|sp|P49014|PRS4_MOUSE 26S
PROTEASE REGULATORY SUBUNIT 4 (P26S4)
>gi|1066067|gb|AAB34137.1| (U39302) P26s4 [Mus musculus]
>gi|1395182|dbj|BAA09341.1| (D50696) proteasomal ATPase
(S4) [Rattus norvegicus]
Length = 440
Score = 365 bits (926), Expect = e-100
Identities = 191/370 (51%), Positives = 257/370 (68%), Gaps = 9/370 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ + IR E Q++ LE E+ E E RS++ LR P GT+ E++D
Sbjct: 66 ERIKDYLLMEEEFIRNQE-QMKPLE---EKQEEE----RSKVDDLRGTPMSVGTLEEIID 117
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D+ AIV G V I ++++D L PG V L+ + A+I +L DP V +V
Sbjct: 118 DNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVE 177
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY DIGGL Q+QE++E++ELPL HPE +EE+GI PPKGV+LYGPPG GKTL+AK
Sbjct: 178 KAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A++ +ATF+RVVGSEL++KY+G+G +LV ELF +A+E AP+I+FIDEIDAIG KR D
Sbjct: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDS 297
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+GGERE+ RT+++LL ++DGFD RG+VKVI ATNR + LDPAL+RPGR DR IE PLPD
Sbjct: 298 NSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 357
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ + I ++HT RM L +V L + + SGAD+KAI TEAG+ A+RERR VT E
Sbjct: 358 EKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE 417
Query: 372 DFLKAVDKVL 381
DF K+ + VL
Sbjct: 418 DFKKSKENVL 427
>pir||T27048 hypothetical protein Y49E10.1 - Caenorhabditis elegans
>gi|3979998|emb|CAB11558.1| (Z98866) contains similarity
to Pfam domain: PF00004 (ATPases associated with various
cellular activities (AAA)), Score=327.8,
E-value=4.1e-95, N=1~cDNA EST yk78f3.3 comes from this
gene~cDNA EST yk91c7.3 comes from this gene~cDNA EST
yk78f3.5 comes fr>
Length = 416
Score = 364 bits (925), Expect = e-100
Identities = 183/376 (48%), Positives = 266/376 (70%), Gaps = 1/376 (0%)
Query: 7 DEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGT 66
DE + + + ++++ VR L+A + L ++ L+ E+ +L + ++ G
Sbjct: 26 DEKTLRKYFSTKVDDAQQKVADKSQNVRRLQAQRNELNTKVRMLKEELQQLHEQGSYVGE 85
Query: 67 VIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTV 126
V + +D + +V+ + ++VV + I+ + L GARVAL + A+ +LLP+ DP V
Sbjct: 86 VSKAMDKKKVLVKVHPEGKYVVDVDKSIDINSLNTGARVALRADSYALHKLLPNKVDPLV 145
Query: 127 LGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCG 186
V + P+ TY +GGL KQ++E++E IELP+KHPELF+ +GI PKGVLL+GPPG G
Sbjct: 146 SLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLFGPPGTG 205
Query: 187 KTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIG 246
KTL+A+A+AH TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG
Sbjct: 206 KTLLARAVAHHTECTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIG 265
Query: 247 AKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLI 306
+ R++ ++GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILDPALLRPGR DR I
Sbjct: 266 SSRVEGSSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKI 325
Query: 307 EVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERR 365
E P PD + R +ILK+H+R+M L + +++ IAE GASGA++K++ TEAGMFA+RERR
Sbjct: 326 EFPAPDEKARADILKIHSRKMNLMRGINMAKIAEQIPGASGAEVKSVCTEAGMFALRERR 385
Query: 366 TYVTQEDFLKAVDKVL 381
+VTQEDF AV KV+
Sbjct: 386 IHVTQEDFEMAVGKVM 401
>emb|CAA61864.1| (X89719) put. 26S protease subunit [Sus scrofa]
Length = 398
Score = 363 bits (922), Expect = 2e-99
Identities = 187/369 (50%), Positives = 263/369 (70%), Gaps = 8/369 (2%)
Query: 21 YLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +I +L+L V R L+A + L ++ LR E+ L++ ++ G V+ +D
Sbjct: 15 YYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDK 74
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ + +FVV + I+ + + P RVAL + + ++LP+ DP V V +
Sbjct: 75 KKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEK 134
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY IGGL KQ++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 135 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARA 194
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG+ R++
Sbjct: 195 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 254
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
+GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILD ALLRPGR DR IE P P+
Sbjct: 255 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 314
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+A+RERR +VTQED
Sbjct: 315 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 374
Query: 373 FLKAVDKVL 381
F AV KV+
Sbjct: 375 FEMAVAKVM 383
>sp|O18413|PRS8_DROME 26S PROTEASE REGULATORY SUBUNIT 8 >gi|2245467|gb|AAC48284.1|
(U97538) DUG [Drosophila melanogaster]
Length = 405
Score = 363 bits (922), Expect = 2e-99
Identities = 186/382 (48%), Positives = 271/382 (70%), Gaps = 9/382 (2%)
Query: 8 EVQFHENYDDYITYLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQP 60
E +H+ + + +Y ++I +L+L V R L+A + L ++ LR E+ L++
Sbjct: 10 ESAYHKG-EGFRSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQ 68
Query: 61 PAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS 120
++ G V++ +D + +V+ + + VV + I+ + + P RVAL + + ++LP+
Sbjct: 69 GSYVGEVVKPMDKKKVLVKVHPEGKSVVDLDKNIDINDVTPNCRVALRNESYTLHKILPN 128
Query: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
DP V V + P+ TY +GGL KQ++E++E IELP+KHPELF+ +GI PKGVLLY
Sbjct: 129 KVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLY 188
Query: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
GPPG GKTL+A+A+AH TFIRV GSELV+K+IGEG+R+V ELF +A+E AP+IIF+D
Sbjct: 189 GPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMD 248
Query: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
EID+IG+ R++ +GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILDPALLRPG
Sbjct: 249 EIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPG 308
Query: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMF 359
R DR IE P P+ E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+
Sbjct: 309 RIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMY 368
Query: 360 AIRERRTYVTQEDFLKAVDKVL 381
A+RERR +VTQEDF AV KV+
Sbjct: 369 ALRERRVHVTQEDFEMAVAKVM 390
>gi|7110703 protease (prosome, macropain) 26S subunit, ATPase 5 [Mus musculus]
>gi|11425146|ref|XP_008254.1| proteasome (prosome,
macropain) 26S subunit, ATPase, 5 [Homo sapiens]
>gi|1709800|sp|P52915|PRS8_MOUSE 26S PROTEASE REGULATORY
SUBUNIT 8 (MSUG1 PROTEIN) (TAT-BINDING PROTEIN HOMOLOG
10) (TBP10) (P45/SUG) >gi|2137798|pir||S61923 SUG1
protein - mouse >gi|1165125|emb|CAA90961.1| (Z54219)
mSUG1 protein [Mus musculus] >gi|1262433|emb|CAA61863.1|
(X89718) 26S protease subunit [Sus scrofa]
>gi|1395177|dbj|BAA11938.1| (D83521) proteasomal ATPase
(rat SUG1) [Rattus norvegicus]
>gi|2564003|dbj|BAA22933.1| (AB000491) proteasome
p45/SUG [Rattus norvegicus] >gi|3193258|gb|AAC19266.1|
(AF069053) proteasome subunit SUG1 [Bos taurus]
Length = 406
Score = 363 bits (922), Expect = 2e-99
Identities = 187/369 (50%), Positives = 263/369 (70%), Gaps = 8/369 (2%)
Query: 21 YLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +I +L+L V R L+A + L ++ LR E+ L++ ++ G V+ +D
Sbjct: 23 YYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDK 82
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ + +FVV + I+ + + P RVAL + + ++LP+ DP V V +
Sbjct: 83 KKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEK 142
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY IGGL KQ++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 143 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARA 202
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG+ R++
Sbjct: 203 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
+GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILD ALLRPGR DR IE P P+
Sbjct: 263 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 322
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+A+RERR +VTQED
Sbjct: 323 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 382
Query: 373 FLKAVDKVL 381
F AV KV+
Sbjct: 383 FEMAVAKVM 391
>sp|P47210|PRS8_HUMAN 26S PROTEASE REGULATORY SUBUNIT 8 (PROTEASOME SUBUNIT P45) (THYROID
HORMONE RECEPTOR INTERACTING PROTEIN 1) (TRIP1)
>gi|2136007|pir||I53510 proteasome subunit p45 - human
>gi|7435734|pir||S65536 26S proteasome chain p45 - human
>gi|976227|dbj|BAA07919.1| (D44467) 26S proteasome
subunit p45 [Homo sapiens] >gi|1096205|prf||2111282A 26S
proteasome [Homo sapiens]
Length = 406
Score = 363 bits (921), Expect = 3e-99
Identities = 187/369 (50%), Positives = 263/369 (70%), Gaps = 8/369 (2%)
Query: 21 YLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +I +L+L V R L+A + L ++ LR E+ L++ ++ G V+ +D
Sbjct: 23 YYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLRRELQLLQEQGSYVGEVVRAMDK 82
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ + +FVV + I+ + + P RVAL + + ++LP+ DP V V +
Sbjct: 83 KKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEK 142
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY IGGL KQ++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 143 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARA 202
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG+ R++
Sbjct: 203 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
+GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILD ALLRPGR DR IE P P+
Sbjct: 263 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 322
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+A+RERR +VTQED
Sbjct: 323 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 382
Query: 373 FLKAVDKVL 381
F AV KV+
Sbjct: 383 FEMAVAKVM 391
>sp|P48601|PRS4_DROME 26S PROTEASE REGULATORY SUBUNIT 4 (P26S4)
>gi|1066065|gb|AAB34134.1| (U39303) P26s4 [Drosophila
melanogaster]
Length = 439
Score = 362 bits (919), Expect = 4e-99
Identities = 185/375 (49%), Positives = 257/375 (68%), Gaps = 9/375 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ IR E L+ E+ E E RS++ LR P G + E++D
Sbjct: 65 ERIKDYLMMEDEFIRNQE----RLKPQDEKNEEE----RSKVDDLRGTPMSVGNLEEIID 116
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D+ AIV G V I ++++D+L PG V L+ + A++ +L DP V ++
Sbjct: 117 DNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTMMKLE 176
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY DIGGL Q+QE++E++ELPL HPE +EE+GI PPKGV+LYGPPG GKTL+AK
Sbjct: 177 KAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 236
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A++ +ATF+RVVGSEL++KY+G+G +LV ELF +A+E AP+I+FIDEIDA+G KR D
Sbjct: 237 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDS 296
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+GGERE+ RT+++LL ++DGFD RG+VKVI ATNR + LDPAL+RPGR DR IE PLPD
Sbjct: 297 NSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 356
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ + I +HT RM L ++V+L + + SGAD+KAI TEAG+ A+RERR VT E
Sbjct: 357 EKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE 416
Query: 372 DFLKAVDKVLGNERK 386
DF K+ + VL +++
Sbjct: 417 DFKKSKESVLYRKKE 431
>pir||T43799 proteasome protein p45/SUG [imported] - rat (fragment)
>gi|2564007|dbj|BAA22935.1| (AB000493) proteasome
p45/SUG [Rattus norvegicus]
Length = 374
Score = 362 bits (919), Expect = 4e-99
Identities = 182/350 (52%), Positives = 256/350 (73%), Gaps = 1/350 (0%)
Query: 33 VRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAP 92
+R L+A + L ++ LR E+ L++ ++ G V+ +D + +V+ + +FVV +
Sbjct: 10 LRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDK 69
Query: 93 WIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQEL 152
I+ + + P RVAL + + ++LP+ DP V V + P+ TY IGGL KQ++E+
Sbjct: 70 NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEI 129
Query: 153 REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVR 212
+E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A+AH + TFIRV GSELV+
Sbjct: 130 KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ 189
Query: 213 KYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMD 272
K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG+ R++ +GG+ EV RT+++LL ++D
Sbjct: 190 KFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLD 249
Query: 273 GFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KN 331
GF+ N+KVI ATNR DILD ALLRPGR DR IE P P+ E RL+ILK+H+R+M L +
Sbjct: 250 GFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRG 309
Query: 332 VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVL 381
++LR IAE+ GASGA++K + TEAGM+A+RERR +VTQEDF AV KV+
Sbjct: 310 INLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVM 359
>gb|AAF56205.1| (AE003745) Pros26.4 gene product [Drosophila melanogaster]
Length = 439
Score = 362 bits (919), Expect = 4e-99
Identities = 185/375 (49%), Positives = 257/375 (68%), Gaps = 9/375 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ IR E L+ E+ E E RS++ LR P G + E++D
Sbjct: 65 ERIKDYLMMEDEFIRNQE----RLKPQDEKNEEE----RSKVDDLRGTPMSVGNLEEIID 116
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D+ AIV G V I ++++D+L PG V L+ + A++ +L DP V ++
Sbjct: 117 DNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLE 176
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY DIGGL Q+QE++E++ELPL HPE +EE+GI PPKGV+LYGPPG GKTL+AK
Sbjct: 177 KAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 236
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A++ +ATF+RVVGSEL++KY+G+G +LV ELF +A+E AP+I+FIDEIDA+G KR D
Sbjct: 237 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDS 296
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+GGERE+ RT+++LL ++DGFD RG+VKVI ATNR + LDPAL+RPGR DR IE PLPD
Sbjct: 297 NSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 356
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ + I +HT RM L ++V+L + + SGAD+KAI TEAG+ A+RERR VT E
Sbjct: 357 EKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE 416
Query: 372 DFLKAVDKVLGNERK 386
DF K+ + VL +++
Sbjct: 417 DFKKSKESVLYRKKE 431
>pir||T49402 probable 26S proteinase subunit (SUG1) protein [imported] -
Neurospora crassa >gi|7800937|emb|CAB91305.1| (AL355928)
probable 26S protease subunit (SUG1) protein [Neurospora
crassa]
Length = 389
Score = 361 bits (918), Expect = 6e-99
Identities = 185/368 (50%), Positives = 261/368 (70%), Gaps = 1/368 (0%)
Query: 15 YDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDD 74
Y + I +K I + + +R LEA + + LR E+ L+QP ++ G V++V+
Sbjct: 7 YHNKIEAMKLEILKGQAVLRRLEAQRNDYNSRVRLLREELGLLQQPGSYVGEVVKVMSTK 66
Query: 75 RAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIER 134
+ +V+ + ++VV ++ ++ KL G RV L + + ++LPSS DP V V +
Sbjct: 67 KVLVKVHPEGKYVVDVSDNVDITKLTVGKRVTLLSDSYKLEKMLPSSVDPLVSLMMVEKV 126
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P+ TY+ IGGL +Q++E++E IEL LKHPELFE +GI PKGVLLYGPPG GKTL+A+A+
Sbjct: 127 PDSTYDMIGGLDQQIKEIKEVIELGLKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAV 186
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
AH + FIRV GSELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ R++ ++
Sbjct: 187 AHHTDCKFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRVEGSS 246
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
GG+ EV RT+++LL ++DGF+P N+KVI ATNR DILDPALLRPGR DR IE P P E
Sbjct: 247 GGDSEVQRTMLELLNQLDGFEPTKNIKVIMATNRLDILDPALLRPGRIDRKIEFPPPSVE 306
Query: 315 GRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDF 373
R +IL++H+R+M L + ++L IAE G SGA+LK + TEAGM+A+RERR +VTQEDF
Sbjct: 307 ARADILRIHSRKMNLTRGINLTKIAEKMNGCSGAELKGVCTEAGMYALRERRVHVTQEDF 366
Query: 374 LKAVDKVL 381
A K+L
Sbjct: 367 ELATAKIL 374
>sp|P54814|PRS8_MANSE 26S PROTEASE REGULATORY SUBUNIT 8 (18-56 PROTEIN)
>gi|1167963|gb|AAC46996.1| (U43728) 18-56 protein
[Manduca sexta]
Length = 402
Score = 361 bits (917), Expect = 7e-99
Identities = 182/372 (48%), Positives = 263/372 (69%), Gaps = 1/372 (0%)
Query: 11 FHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEV 70
F Y I L+ + + +R L+A + L ++ LR E+ L++ ++ G V++
Sbjct: 16 FRPYYITKIEELQLIVAEKSQNLRRLQAQRNELNAKVRMLREELQLLQEQGSYVGEVVKP 75
Query: 71 LDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFE 130
+D + +V+ + +FVV + ++ + + RVAL + + ++LP+ DP V
Sbjct: 76 MDKKKVLVKVHPEGKFVVDLDKNVDINDVTANCRVALRNESYTLHKILPNKVDPLVSLMM 135
Query: 131 VIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLM 190
V + P+ TY +GGL KQ++E++E IELP+KHPELF+ +GI PKGVLLYGPPG GKTL+
Sbjct: 136 VEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLL 195
Query: 191 AKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRM 250
A+A+AH TFIRV GSELV+K+IGEG+R+V ELF +A+E AP+IIF+DEID+IG+ R+
Sbjct: 196 ARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRI 255
Query: 251 DETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
+ +GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILDPALLRPGR DR IE P
Sbjct: 256 ESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPP 315
Query: 311 PDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
P+ E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+A+RERR +VT
Sbjct: 316 PNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVT 375
Query: 370 QEDFLKAVDKVL 381
QEDF AV KV+
Sbjct: 376 QEDFEMAVAKVM 387
>pir||T33633 hypothetical protein F56F11.4 - Caenorhabditis elegans
>gi|3790757|gb|AAC71778.1| (AF099922) similar to the AAA
family of ATPases; most similar to 26S protease
regulatory subunit 8 [Caenorhabditis elegans]
Length = 443
Score = 360 bits (915), Expect = 1e-98
Identities = 189/392 (48%), Positives = 267/392 (67%), Gaps = 18/392 (4%)
Query: 8 EVQFHEN--------------YDDYITYLKRRIRQL---ELQVRMLEADKERLERELSRL 50
EV F EN +D+ + +L +++ + + VR L A ++ L ++ L
Sbjct: 37 EVNFRENNWKKRIISQKKNQVFDEKLKFLIEKLQTVAEKSINVRRLMAQQKELNGKVRLL 96
Query: 51 RSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQR 110
+ E+S L + + G V + +D + +V+N+ +++V +A ++ L G RVAL
Sbjct: 97 KEEISHLHEQGSHVGEVCKAMDKKKVLVKNHPDGKYIVDVAASVDISTLAAGTRVALRAD 156
Query: 111 TMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVG 170
AI E+LPS DP V V + P+ TY +GGL Q++E++E IELP+KHPELF+ +G
Sbjct: 157 NYAIHEVLPSKVDPLVSLMMVEKVPDSTYEMVGGLDTQIKEIKEVIELPVKHPELFDALG 216
Query: 171 IDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAK 230
I PKGVLLYGPPG GKTL+A+A+AH TFIRV GSELV+K+IGEGAR+V ELF +A+
Sbjct: 217 IAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGARMVRELFVMAR 276
Query: 231 EKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPD 290
E AP+IIF+DEID+IG+ R++ + GG+ EV RT+++LL ++DGF+ N+KVI ATNR D
Sbjct: 277 EHAPSIIFMDEIDSIGSSRVEGSRGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRID 336
Query: 291 ILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADL 349
ILD ALLRPGR DR IE P PD + R +ILK+H+R+M L + + + IAE GASGA++
Sbjct: 337 ILDSALLRPGRIDRKIEFPAPDEKARAQILKIHSRKMNLMRGIRMDKIAEQIPGASGAEV 396
Query: 350 KAIATEAGMFAIRERRTYVTQEDFLKAVDKVL 381
K++ TEAGMFA+RERR +VTQEDF AV KV+
Sbjct: 397 KSVCTEAGMFALRERRIHVTQEDFEMAVGKVM 428
>sp|Q90732|PRS4_CHICK 26S PROTEASE REGULATORY SUBUNIT 4 (P26S4) >gi|7435735|pir||S74197
ATP-dependent 26S proteinase regulatory subunit 4 -
chicken >gi|1399943|gb|AAC60013.1| (U60187) 26S ATPase
complex subunit 4 [Gallus gallus]
Length = 440
Score = 360 bits (915), Expect = 1e-98
Identities = 188/370 (50%), Positives = 255/370 (68%), Gaps = 9/370 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ + IR E Q++ LE E+ E E RS++ LR P GT+ E++D
Sbjct: 66 ERIKDYLLMEEEFIRNQE-QMKPLE---EKQEEE----RSKVDDLRGTPMSVGTLEEIID 117
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D+ AIV G V I ++++D L PG V L+ + A+I +L DP V ++
Sbjct: 118 DNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKLE 177
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY DIGGL Q+QE++E++ELPL HPE +EE+GI PPKGV+LYGPPG GKTL+AK
Sbjct: 178 KAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A++ +ATF+RVVGSEL++KY+G+G +LV ELF +A+E P+I+FIDEIDAIG KR D
Sbjct: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHGPSIVFIDEIDAIGTKRYDS 297
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+GGERE+ RT+++LL ++DGFD RG+VKVI ATNR + LDPAL+RPGR DR IE PLPD
Sbjct: 298 NSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 357
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ + I ++HT RM L +V L + + SGAD+KAI TEAG+ A+RERR VT E
Sbjct: 358 EKTKKRIFQIHTSRMTLADDVTLDELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE 417
Query: 372 DFLKAVDKVL 381
DF K+ + L
Sbjct: 418 DFKKSKENFL 427
>emb|CAC14432.1| (AJ291500) 26S proteasome subunit 4-like protein [Brassica napus]
Length = 443
Score = 360 bits (914), Expect = 2e-98
Identities = 179/366 (48%), Positives = 258/366 (69%), Gaps = 4/366 (1%)
Query: 25 RIRQLELQVRMLEADKERL---ERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
RI+ L A++ERL E + RS++ LR P G + E++D++ AIV +
Sbjct: 70 RIKDYLLMEEEFVANQERLKPQEEKAEEDRSKVDDLRGTPMSVGNLEELIDENHAIVSSS 129
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
GP + V I ++++D+L PG + + + ++++ +L DP V +V + P +Y D
Sbjct: 130 VGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVSVMKVEKAPLESYAD 189
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGGL+ Q+QE++EA+ELPL HPEL+E++GI PPKGV+LYG PG GKTL+AKA+A+ +AT
Sbjct: 190 IGGLEAQIQEIKEAVELPLTHPELYEDIGIKPPKGVILYGEPGTGKTLLAKAVANSTSAT 249
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
F+RVVGSEL++KY+G+G +LV ELF +A + +P+I+FIDEIDA+G KR D +GGERE+
Sbjct: 250 FLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDANSGGEREIQ 309
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
RT+++LL ++DGFD RG+VKVI ATNR + LDPALLRPGR DR IE PLPD + R I +
Sbjct: 310 RTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQ 369
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
+HT +M L ++V+L + SGAD+KAI TEAG+ A+RERR VT DF KA +KV
Sbjct: 370 IHTSKMTLSEDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHPDFKKAKEKV 429
Query: 381 LGNERK 386
+ +++
Sbjct: 430 MFKKKE 435
>gb|AAF69154.1|AC007915_6 (AC007915) F27F5.8 [Arabidopsis thaliana]
Length = 399
Score = 360 bits (914), Expect = 2e-98
Identities = 182/374 (48%), Positives = 253/374 (66%), Gaps = 3/374 (0%)
Query: 27 RQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRF 86
++LE +VR + ++E ++ ++ L+ G V+ LD++R IV+ +GPR+
Sbjct: 26 KELESRVRTARENLRAAKKEFNKTEDDLKSLQSVGQIIGEVLRPLDNERLIVKASSGPRY 85
Query: 87 VVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLK 146
VV ++++KL G RV LD T+ I+ LP DP V + N++Y+ +GGL
Sbjct: 86 VVGCRSKVDKEKLTSGTRVVLDMTTLTIMRALPREVDPVVYNMLHEDPGNISYSAVGGLG 145
Query: 147 KQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV 206
Q++ELRE+IELPL +PELF VGI PPKGVLLYGPPG GKTL+A+A+A ++A F++VV
Sbjct: 146 DQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKVV 205
Query: 207 GSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ 266
S ++ KYIGE ARL+ E+F A+E P IIF+DEIDAIG +R E T +RE+ RTLM+
Sbjct: 206 SSAIIDKYIGESARLIREMFNYAREHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLME 265
Query: 267 LLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRR 326
LL ++DGFD G VK+I ATNRPD+LDPALLRPGR DR IE+PLP+ + R+EILK+H
Sbjct: 266 LLNQLDGFDQLGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQSRMEILKIHASG 325
Query: 327 M-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNER 385
+ K +D I ++ EG +GADL+ I TEAGMFAIR R YV EDF+KAV K+ +E
Sbjct: 326 IAKHGEIDYEAIVKLGEGFNGADLRNICTEAGMFAIRAERDYVIHEDFMKAVRKL--SEA 383
Query: 386 KLLQQITSHEIIYG 399
K L+ + + +G
Sbjct: 384 KKLESSSHYNADFG 397
>gb|AAD24384.1|AC006081_20 (AC006081) 26S proteasome subunit 4 [Arabidopsis thaliana]
Length = 443
Score = 360 bits (913), Expect = 2e-98
Identities = 179/366 (48%), Positives = 258/366 (69%), Gaps = 4/366 (1%)
Query: 25 RIRQLELQVRMLEADKERL---ERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
RI+ L A++ERL E + RS++ LR P G + E++D++ AIV +
Sbjct: 70 RIKDYLLMEEEFVANQERLKPQEEKAEEDRSKVDDLRGTPMSVGNLEELIDENHAIVSSS 129
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
GP + V I ++++D+L PG + + + ++++ +L DP V +V + P +Y D
Sbjct: 130 VGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVSVMKVEKAPLESYAD 189
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGGL+ Q+QE++EA+ELPL HPEL+E++GI PPKGV+LYG PG GKTL+AKA+A+ +AT
Sbjct: 190 IGGLEAQIQEIKEAVELPLTHPELYEDIGIKPPKGVILYGEPGTGKTLLAKAVANSTSAT 249
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
F+RVVGSEL++KY+G+G +LV ELF +A + +P+I+FIDEIDA+G KR D +GGERE+
Sbjct: 250 FLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDANSGGEREIQ 309
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
RT+++LL ++DGFD RG+VKVI ATNR + LDPALLRPGR DR IE PLPD + R I +
Sbjct: 310 RTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQ 369
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
+HT +M L ++V+L + SGAD+KAI TEAG+ A+RERR VT DF KA +KV
Sbjct: 370 IHTSKMTLAEDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHVDFKKAKEKV 429
Query: 381 LGNERK 386
+ +++
Sbjct: 430 MFKKKE 435
>gb|AAF22522.1|AF123391_1 (AF123391) 26S proteasome AAA-ATPase subunit RPT2a [Arabidopsis
thaliana]
Length = 443
Score = 359 bits (912), Expect = 3e-98
Identities = 179/366 (48%), Positives = 258/366 (69%), Gaps = 4/366 (1%)
Query: 25 RIRQLELQVRMLEADKERL---ERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
RI+ L A++ERL E + RS++ LR P G + E++D++ AIV +
Sbjct: 70 RIKDYLLMEEEFVANQERLKPQEEKAEEDRSKVDDLRGTPMSVGNLEELIDENHAIVSSS 129
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
GP + V I ++++D+L PG + + + ++++ +L DP V +V + P +Y D
Sbjct: 130 VGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVSVMKVEKAPLESYAD 189
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGGL+ Q+QE++EA+ELPL HPEL+E++GI PPKGV+LYG PG GKTL+AKA+A+ +AT
Sbjct: 190 IGGLEAQIQEIKEAVELPLTHPELYEDIGIKPPKGVILYGEPGTGKTLLAKAVANSTSAT 249
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
F+RVVGSEL++KY+G+G +LV ELF +A + +P+I+FIDEIDA+G KR D +GGERE+
Sbjct: 250 FLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQ 309
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
RT+++LL ++DGFD RG+VKVI ATNR + LDPALLRPGR DR IE PLPD + R I +
Sbjct: 310 RTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQ 369
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
+HT +M L ++V+L + SGAD+KAI TEAG+ A+RERR VT DF KA +KV
Sbjct: 370 IHTSKMTLSEDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHPDFKKAKEKV 429
Query: 381 LGNERK 386
+ +++
Sbjct: 430 MFKKKE 435
>pir||T08959 proteinase homolog F19B15.70 - Arabidopsis thaliana
>gi|4972050|emb|CAB43918.1| (AL078470) 26S proteasome
subunit 4-like protein [Arabidopsis thaliana]
>gi|7269802|emb|CAB79662.1| (AL161574) 26S proteasome
subunit 4-like protein [Arabidopsis thaliana]
Length = 443
Score = 359 bits (912), Expect = 3e-98
Identities = 179/366 (48%), Positives = 258/366 (69%), Gaps = 4/366 (1%)
Query: 25 RIRQLELQVRMLEADKERL---ERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
RI+ L A++ERL E + RS++ LR P G + E++D++ AIV +
Sbjct: 70 RIKDYLLMEEEFVANQERLKPQEEKAEEDRSKVDDLRGTPMSVGNLEELIDENHAIVSSS 129
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
GP + V I ++++D+L PG + + + ++++ +L DP V +V + P +Y D
Sbjct: 130 VGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVSVMKVEKAPLESYAD 189
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGGL+ Q+QE++EA+ELPL HPEL+E++GI PPKGV+LYG PG GKTL+AKA+A+ +AT
Sbjct: 190 IGGLEAQIQEIKEAVELPLTHPELYEDIGIKPPKGVILYGEPGTGKTLLAKAVANSTSAT 249
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
F+RVVGSEL++KY+G+G +LV ELF +A + +P+I+FIDEIDA+G KR D +GGERE+
Sbjct: 250 FLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQ 309
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
RT+++LL ++DGFD RG+VKVI ATNR + LDPALLRPGR DR IE PLPD + R I +
Sbjct: 310 RTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQ 369
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
+HT +M L ++V+L + SGAD+KAI TEAG+ A+RERR VT DF KA +KV
Sbjct: 370 IHTSKMTLSEDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHPDFKKAKEKV 429
Query: 381 LGNERK 386
+ +++
Sbjct: 430 MFKKKE 435
>gi|4506213 proteasome (prosome, macropain) 26S subunit, ATPase, 5 [Homo
sapiens] >gi|2136322|pir||S60343 Trip1 protein - human
>gi|695370|gb|AAC41735.1| (L38810) thyroid receptor
interactor [Homo sapiens] >gi|1094810|prf||2106382A
thyroid hormone receptor-interacting protein [Homo
sapiens]
Length = 406
Score = 359 bits (911), Expect = 4e-98
Identities = 185/369 (50%), Positives = 261/369 (70%), Gaps = 8/369 (2%)
Query: 21 YLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +I +L+L V R L+A + L ++ LR E+ L++ ++ G V+ +D
Sbjct: 23 YYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDK 82
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ + +FVV + I+ + + P RVAL + + ++LP+ DP V V +
Sbjct: 83 KKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEK 142
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY IGGL KQ++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 143 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARA 202
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG+ R++
Sbjct: 203 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
+GG EV R +++LL ++DGF+ N+KVI ATNR D+LD ALLRPGR DR IE P P+
Sbjct: 263 SGGSSEVQRQMLELLNQLDGFEATKNIKVIMATNRIDMLDSALLRPGRIDRKIEFPPPNE 322
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+A+RERR +VTQED
Sbjct: 323 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 382
Query: 373 FLKAVDKVL 381
F AV KV+
Sbjct: 383 FEMAVAKVM 391
>gb|AAF22524.1|AF123393_1 (AF123393) 26S proteasome AAA-ATPase subunit RPT4a [Arabidopsis
thaliana] >gi|9758590|dbj|BAB09203.1| (AB008264) 26S
proteasome AAA-ATPase subunit RPT4a [Arabidopsis
thaliana]
Length = 399
Score = 359 bits (911), Expect = 4e-98
Identities = 181/374 (48%), Positives = 253/374 (67%), Gaps = 3/374 (0%)
Query: 27 RQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRF 86
++LE +VR + ++E ++ ++ L+ G V+ LD++R IV+ +GPR+
Sbjct: 26 KELESRVRTARENLRGAKKEFNKTEDDLKSLQSVGQIIGEVLRPLDNERLIVKASSGPRY 85
Query: 87 VVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLK 146
VV ++++KL G RV LD T+ I+ LP DP V + N++Y+ +GGL
Sbjct: 86 VVGCRSKVDKEKLTSGTRVVLDMTTLTIMRALPREVDPVVYNMLHEDPGNISYSAVGGLG 145
Query: 147 KQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV 206
Q++ELRE+IELPL +PELF VGI PPKGVLLYGPPG GKTL+A+A+A ++A F++VV
Sbjct: 146 DQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKVV 205
Query: 207 GSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ 266
S ++ KYIGE ARL+ E+F A+E P IIF+DEIDAIG +R E T +RE+ RTLM+
Sbjct: 206 SSAIIDKYIGESARLIREMFNYAREHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLME 265
Query: 267 LLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRR 326
LL ++DGFD G VK+I ATNRPD+LDPALLRPGR DR IE+PLP+ + R++ILK+H
Sbjct: 266 LLNQLDGFDNLGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQSRMDILKIHAAG 325
Query: 327 M-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNER 385
+ K +D I ++ EG +GADL+ I TEAGMFAIR R YV EDF+KAV K+ +E
Sbjct: 326 IAKHGEIDYEAIVKLAEGFNGADLRNICTEAGMFAIRAERDYVIHEDFMKAVRKL--SEA 383
Query: 386 KLLQQITSHEIIYG 399
K L+ + + +G
Sbjct: 384 KKLESSSHYNADFG 397
>sp|P34124|PRS8_DICDI 26S PROTEASE REGULATORY SUBUNIT 8 (TAT-BINDING PROTEIN HOMOLOG 10)
>gi|422297|pir||JN0610 probable transcription factor
DdTBP10 - slime mold (Dictyostelium discoideum)
(fragment) >gi|290057|gb|AAA33254.1| (L16579) HIV1
TAT-binding protein [Dictyostelium discoideum]
Length = 389
Score = 358 bits (910), Expect = 5e-98
Identities = 182/370 (49%), Positives = 260/370 (70%), Gaps = 2/370 (0%)
Query: 14 NYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
+Y I L+ ++ + +R LEA + L + L+ E+ L P + V++++
Sbjct: 5 DYCSKIEELEIKVNEKAQDLRRLEAQRNELNNRVRMLKEELQLLTNPGSHVAEVVKLMGK 64
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
++ +V+ +FVV I P ++ KL P R AL + + +LP+ DP V +V +
Sbjct: 65 NKVLVKVNPEGKFVVDIDPTVDIAKLTPSTRAALKHESYTLHRILPNKIDPLVSLMKVEK 124
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY+ +GGL KQ++E++E IELP+KHPELFE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 125 IPDSTYDMVGGLDKQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARA 184
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE- 252
+AH + TFIRV GSELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ R +
Sbjct: 185 VAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFIMAREHAPSIIFMDEIDSIGSSRGESG 244
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+ GG+ EV RT+++LL ++DGF+ N+KV+ TNR DILDPALLRPGR DR IE P P
Sbjct: 245 SGGGDSEVQRTMLELLNQLDGFESTKNIKVLMCTNRIDILDPALLRPGRIDRKIEFPNPG 304
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GRL+ILK+H+R+M L + ++L+ I++ GASGA+LKA+ TEAGM+A+RERR +V+QE
Sbjct: 305 DAGRLDILKIHSRKMNLTRGINLKKISDKMNGASGAELKAVCTEAGMYALRERRVHVSQE 364
Query: 372 DFLKAVDKVL 381
DF AV KV+
Sbjct: 365 DFEMAVSKVM 374
>sp|O16368|PRS4_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT 4 >gi|7500175|pir||T31800
hypothetical protein F29G9.5 - Caenorhabditis elegans
>gi|2315358|gb|AAB65906.1| (AF016440) strong similarity
to the AAA family of ATPases [Caenorhabditis elegans]
Length = 443
Score = 358 bits (908), Expect = 8e-98
Identities = 180/375 (48%), Positives = 258/375 (68%), Gaps = 9/375 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ + I+ E L+ +ER E E R+++ LR P G++ E++D
Sbjct: 69 ERIKDYLLMEQEFIQNQE----RLKPQEERQEEE----RAKVDELRGTPMAVGSLEEIID 120
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D AIV G V I ++++++L PG V L+ + A+I +L DP V ++
Sbjct: 121 DQHAIVSTNVGSEHYVNIMSFVDKEQLEPGCSVLLNHKNHAVIGVLSDDTDPMVSVMKLE 180
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY D+GGL +Q+QE++EA+ELPL HPE +EE+GI PPKGV+LYG PG GKTL+AK
Sbjct: 181 KAPQETYADVGGLDQQIQEIKEAVELPLTHPEYYEEMGIRPPKGVILYGCPGTGKTLLAK 240
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A++ +ATF+R+VGSEL++KY+G+G ++V ELF +A+E AP+I+FIDEIDA+G KR D
Sbjct: 241 AVANQTSATFLRIVGSELIQKYLGDGPKMVRELFRVAEENAPSIVFIDEIDAVGTKRYDS 300
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
+GGERE+ RT+++LL ++DGFD RG+VKV+ ATNR + LDPAL+RPGR DR IE PLPD
Sbjct: 301 NSGGEREIQRTMLELLNQLDGFDSRGDVKVLMATNRIESLDPALIRPGRIDRKIEFPLPD 360
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ + I ++HT RM L K V+L + SGAD+KA+ TEAG+ A+RERR VT E
Sbjct: 361 EKTKRRIFQIHTSRMTLGKEVNLEEFITAKDELSGADIKAMCTEAGLLALRERRMRVTME 420
Query: 372 DFLKAVDKVLGNERK 386
DF K+ + VL +++
Sbjct: 421 DFQKSKENVLYRKKE 435
>sp|P46466|PRS4_ORYSA 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG (TAT-BINDING PROTEIN
HOMOLOG 2) >gi|7435744|pir||T03776 tat binding protein
homolog - rice >gi|556558|dbj|BAA04615.1| (D17789) rice
homologue of Tat binding protein [Oryza sativa]
Length = 448
Score = 357 bits (906), Expect = 1e-97
Identities = 179/366 (48%), Positives = 255/366 (68%), Gaps = 4/366 (1%)
Query: 25 RIRQLELQVRMLEADKERL---ERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
R++ L A +ERL E + RS++ LR P G++ E++D+ AIV +
Sbjct: 75 RVKDYLLMEEEFVAAQERLRPTEDKTEEDRSKVDDLRGTPMSVGSLEEIIDESHAIVSSS 134
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
GP + V I ++++D+L PG + + + ++++ +L DP V +V + P +Y D
Sbjct: 135 VGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVSVMKVEKAPLESYAD 194
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGGL Q+QE++EA+ELPL HPEL+E++GI PPKGV+LYG PG GKTL+AKA+A+ +AT
Sbjct: 195 IGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSAT 254
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
F+RVVGSEL++KY+G+G +LV ELF +A E +P+I+FIDEIDA+G KR D +GGERE+
Sbjct: 255 FLRVVGSELIQKYLGDGPKLVRELFRVADELSPSIVFIDEIDAVGTKRYDAHSGGEREIQ 314
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
RT+++LL ++DGFD RG+VKVI ATNR + LDPALLRPGR DR IE PLPD + R I +
Sbjct: 315 RTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQ 374
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
+HT +M L +V+L + SGAD+KAI TEAG+ A+RERR VT DF KA +KV
Sbjct: 375 IHTSKMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADFKKAKEKV 434
Query: 381 LGNERK 386
+ +++
Sbjct: 435 MFKKKE 440
>gb|AAF57069.1| (AE003774) CG2241 gene product [Drosophila melanogaster]
Length = 399
Score = 357 bits (906), Expect = 1e-97
Identities = 182/372 (48%), Positives = 262/372 (69%), Gaps = 2/372 (0%)
Query: 11 FHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEV 70
FH Y I+ L+ + + + + L+A + L ++ LR E+ L++ ++ V++
Sbjct: 14 FHSYYTQKISELQFTVNERQKNLLRLQAQRNELNLKVRLLREELQLLQEQGSYIAEVVKP 73
Query: 71 LDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFE 130
+D ++ +V+ + ++VV + I + P +RVAL + + ++LP+ DP V
Sbjct: 74 MDKNKVLVKVHPEGKYVVDVDKTINIKDVTPSSRVALRNESYTLHKILPNKVDPLVSLML 133
Query: 131 VIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLM 190
V + P+ TY +GGL KQ+QE++E IELP+KHPELF+ +GI PKGVLLYGPPG GKTL+
Sbjct: 134 VEKVPDSTYEMVGGLDKQIQEIKEVIELPVKHPELFDALGITQPKGVLLYGPPGTGKTLL 193
Query: 191 AKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRM 250
A+A+AH TFIRV GSELV+K+IGEG+R+V ELF +A+E AP+IIF+DEID+IG+ R+
Sbjct: 194 ARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARL 253
Query: 251 DETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
ET G+ EV RT+++LL ++DGF+ N+KVI ATNR D+LD ALLRPGR DR IE P
Sbjct: 254 -ETGTGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDVLDQALLRPGRIDRKIEFPP 312
Query: 311 PDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
P+ E RL+ILK+H+R+M L + ++LR IAE GASGA++K + TEAGM+A+RERR +VT
Sbjct: 313 PNEEARLDILKIHSRKMNLTRGINLRKIAEEMPGASGAEVKGVCTEAGMYALRERRVHVT 372
Query: 370 QEDFLKAVDKVL 381
QEDF AV KV+
Sbjct: 373 QEDFEMAVSKVM 384
>gb|AAF46146.1| (AE003437) Rpt4 gene product [Drosophila melanogaster]
Length = 397
Score = 356 bits (904), Expect = 2e-97
Identities = 183/368 (49%), Positives = 251/368 (67%), Gaps = 3/368 (0%)
Query: 21 YLKRRIRQLELQVRMLEADKE--RLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIV 78
Y K+ + E++ R+ E +E L + + +++ L+ G V++ L +D+ IV
Sbjct: 20 YRKKLLEHKEIEGRLKEKREEIKDLTKLYDKSENDLKALQSVGQIVGEVLKQLTEDKFIV 79
Query: 79 QNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVT 138
+ NGPR+VV +++ KL+ G RVALD T+ I+ LP DP V + +VT
Sbjct: 80 KATNGPRYVVGCRRQLDKAKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGDVT 139
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
Y+ IGGL Q++ELRE IELPL +PELF VGI PPKG LLYGPPG GKTL+A+A+A ++
Sbjct: 140 YSAIGGLTDQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQL 199
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
+A F++VV S +V KYIGE ARL+ E+F A++ P IIF+DEIDAIG +R E T +R
Sbjct: 200 DANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADR 259
Query: 259 EVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
E+ RTLM+LL +MDGFD G VK+I ATNRPD LDPALLRPGR DR IE+PLP+ + RLE
Sbjct: 260 EIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLE 319
Query: 319 ILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAV 377
ILK+H ++ K +D I ++++ +GADL+ + TEAG+FAIR R YV QEDF+KAV
Sbjct: 320 ILKIHALKIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVIQEDFMKAV 379
Query: 378 DKVLGNER 385
KV N++
Sbjct: 380 RKVSDNKK 387
>sp|P46470|PRS8_XENLA 26S PROTEASE REGULATORY SUBUNIT 8 (SUG1 HOMOLOG) (XSUG1)
>gi|1877414|emb|CAA57512.1| (X81986) XSUG1 [Xenopus
laevis]
Length = 461
Score = 355 bits (902), Expect = 4e-97
Identities = 186/369 (50%), Positives = 261/369 (70%), Gaps = 9/369 (2%)
Query: 21 YLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +I L+L V R L+A + L ++ LR E+ L++ ++ G V+ +D
Sbjct: 18 YYLSKIEDLQLVVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDK 77
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ + +FVV + I+ + + P RVAL + + ++LP+ DP V V +
Sbjct: 78 KKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEK 137
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY IGGL KQ++E++E IELP+KHPE FE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 138 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPEHFEALGIAQPKGVLLYGPPGTGKTLLARA 197
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG+ R++
Sbjct: 198 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGS-RLEGG 256
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
+GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILD ALLRPGR DR IE P P+
Sbjct: 257 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 316
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+A+RERR +VTQED
Sbjct: 317 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 376
Query: 373 FLKAVDKVL 381
F AV KV+
Sbjct: 377 FEMAVAKVM 385
>dbj|BAB17625.1| (AB033536) 26S proteasome regulatory particle triple-A ATPase
subunit4 [Oryza sativa]
Length = 400
Score = 355 bits (901), Expect = 6e-97
Identities = 176/374 (47%), Positives = 252/374 (67%), Gaps = 3/374 (0%)
Query: 27 RQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRF 86
R+LE +V + + + +++ ++ ++ L+ G V+ LD++R IV+ +GPR+
Sbjct: 27 RELESRVSTVRENLKNAKKDFTKTEDDLKSLQSVGQIIGEVLRPLDNERFIVKASSGPRY 86
Query: 87 VVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLK 146
VV ++++KL G RV LD T+ I+ LP DP V + NV+Y+ +GGL
Sbjct: 87 VVGCRSKVDKEKLTSGTRVVLDMTTLTIMRTLPREVDPVVYNMLHEDPGNVSYSAVGGLS 146
Query: 147 KQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV 206
Q++ELRE+IELPL +PELF VGI PPKGVLLYGPPG GKTL+A+A+A ++A F+++V
Sbjct: 147 DQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKIV 206
Query: 207 GSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ 266
S ++ KYIGE ARL+ E+F A++ P IIF+DEIDAIG +R E T +RE+ RTLM+
Sbjct: 207 SSAIIDKYIGESARLIREMFGYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLME 266
Query: 267 LLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRR 326
LL ++DGFD G VK+I ATNRPD+LDPALLRPGR DR IE+PLP+ + R+E+LK+H
Sbjct: 267 LLNQLDGFDELGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQARMEVLKIHAAG 326
Query: 327 M-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNER 385
+ K +D + ++ EG +GADL+ + TEAGM AIR R YV EDF+KAV K+ N+
Sbjct: 327 IAKHGEIDYEAVVKLAEGFNGADLRNVCTEAGMAAIRAERDYVVHEDFMKAVRKL--NDA 384
Query: 386 KLLQQITSHEIIYG 399
K L+ + +G
Sbjct: 385 KKLESSAHYSADFG 398
>sp|Q25544|PRS8_NAEFO 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG (TAT-BINDING PROTEIN
HOMOLOG) >gi|1353667|gb|AAB01762.1| (U41812) Tat-binding
protein homolog [Naegleria fowleri]
Length = 414
Score = 354 bits (900), Expect = 7e-97
Identities = 179/351 (50%), Positives = 254/351 (71%), Gaps = 2/351 (0%)
Query: 33 VRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAP 92
+R L+A + L + L+ E+ +L++P + G V++V+ + +++ +++V I
Sbjct: 49 LRRLQAQRNELNGRVRSLKEELQQLQEPGSHVGEVVKVMGKKKVLIKISQEGKYIVDIDK 108
Query: 93 WIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQEL 152
IE L PG RVAL + A+ ++LP+ DP V +V + P+ TY +GGL +Q++E+
Sbjct: 109 SIELKDLTPGVRVALRNDSYALHKILPNKIDPLVSLMKVEKVPDATYEMVGGLDEQIKEI 168
Query: 153 REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVR 212
+E IELP+KHPELFE +GI PKGV++YGPPG GKTL+A+A+AH + TFIRV GSELV+
Sbjct: 169 KEVIELPIKHPELFESLGIAQPKGVIMYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ 228
Query: 213 KYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD-ETTGGEREVNRTLMQLLAEM 271
KYIGEG+++V ELF +A+E AP+IIF+DEID+IG+ R + GG+ EV RT+++LL ++
Sbjct: 229 KYIGEGSKMVRELFVMAREHAPSIIFMDEIDSIGSTRTEGGKGGGDSEVQRTMLELLNQL 288
Query: 272 DGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-K 330
DGF+ N+K+I ATNR DILDPALLRPGR DR IE P P+ RL+ILK+H+RRM L +
Sbjct: 289 DGFESTQNIKIIMATNRIDILDPALLRPGRIDRKIEFPNPNELARLDILKIHSRRMNLTR 348
Query: 331 NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVL 381
++LR IA + GASGA++KA TEAGMFA+RERR +VTQED AV KV+
Sbjct: 349 GINLRKIASMLGGASGAEIKATCTEAGMFALRERRVHVTQEDLEMAVAKVM 399
>gi|6321390 ATPase; Rpt6p [Saccharomyces cerevisiae]
>gi|1709801|sp|Q01939|PRS8_YEAST 26S PROTEASE REGULATORY
SUBUNIT 8 HOMOLOG (SUG1 PROTEIN) (CIM3 PROTEIN)
(TAT-BINDING PROTEIN TBY1) >gi|2133183|pir||S64052 26S
proteasome regulatory particle chain RPT6 - yeast
(Saccharomyces cerevisiae) >gi|172878|gb|AAA35138.1|
(L01626) Tat-binding protein [Saccharomyces cerevisiae]
>gi|1322539|emb|CAA96750.1| (Z72570) ORF YGL048c
[Saccharomyces cerevisiae]
Length = 405
Score = 354 bits (899), Expect = 1e-96
Identities = 178/374 (47%), Positives = 263/374 (69%), Gaps = 8/374 (2%)
Query: 21 YLKRRIRQLELQ-------VRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +++I++ EL+ VR LEA + L ++ ++ E+ L++P ++ G VI+++ D
Sbjct: 22 YFEQKIQETELKIRSKTENVRRLEAQRNALNDKVRFIKDELRLLQEPGSYVGEVIKIVSD 81
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ +++V +A I L+ RV L + + ++L + DP V V +
Sbjct: 82 KKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEK 141
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY+ +GGL KQ++E++E IELP+KHPELFE +GI PKGV+LYGPPG GKTL+A+A
Sbjct: 142 VPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARA 201
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + FIRV G+ELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ R++ +
Sbjct: 202 VAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGS 261
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
GG+ EV RT+++LL ++DGF+ N+K+I ATNR DILDPALLRPGR DR IE P P
Sbjct: 262 GGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSV 321
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
R EIL++H+R+M L + ++LR +AE G SGAD+K + TEAGM+A+RERR +VTQED
Sbjct: 322 AARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQED 381
Query: 373 FLKAVDKVLGNERK 386
F AV KV+ ++
Sbjct: 382 FELAVGKVMNKNQE 395
>gb|AAF08391.1|AF145310_1 (AF145310) 26S proteasome regulatory complex subunit p42D
[Drosophila melanogaster]
Length = 390
Score = 354 bits (899), Expect = 1e-96
Identities = 183/368 (49%), Positives = 249/368 (66%), Gaps = 3/368 (0%)
Query: 21 YLKRRIRQLELQVRMLEADKE--RLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIV 78
Y K+ + E++ R+ E +E L + + +++ L+ G V++ L +D+ IV
Sbjct: 13 YRKKLLEHKEIEGRLKEKREEIKDLTKLYDKSENDLKALQSVGQIVGEVLKQLTEDKFIV 72
Query: 79 QNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVT 138
+ NGPR+VV +++ KL+ G RVALD T+ I+ LP DP V +VT
Sbjct: 73 KATNGPRYVVGCRRQLDKAKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMSHEAPGDVT 132
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
Y+ IGGL Q++ELRE IELPL +PELF VGI PPKG LLYGPPG GKTL+A+A+A ++
Sbjct: 133 YSAIGGLTDQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQL 192
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
+A F++VV S +V KYIGE ARL+ E+F A++ P IIF+DEIDAIG +R E T +R
Sbjct: 193 DANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADR 252
Query: 259 EVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
E+ RTLM+LL +MDGFD G VK+I ATNRPD LDPALLRPGR DR IE+PLP+ + RLE
Sbjct: 253 EIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLE 312
Query: 319 ILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAV 377
ILK+H ++ K +D I ++++ +GADL+ + TEAG FAIR R YV QEDF+KAV
Sbjct: 313 ILKIHALKIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGFFAIRAEREYVIQEDFMKAV 372
Query: 378 DKVLGNER 385
KV N++
Sbjct: 373 RKVSDNKK 380
>prf||1813279A SUG1 gene [Saccharomyces cerevisiae]
Length = 400
Score = 354 bits (898), Expect = 1e-96
Identities = 177/374 (47%), Positives = 263/374 (69%), Gaps = 8/374 (2%)
Query: 21 YLKRRIRQLELQVRM-------LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +++I++ EL++R LEA + L ++ ++ E+ L++P ++ G VI+++ D
Sbjct: 22 YFEQKIQETELKIRSKTENGRRLEAQRNALNDKVRFIKDELRLLQEPGSYVGEVIKIVSD 81
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ +++V +A I L+ RV L + + ++L + DP V V +
Sbjct: 82 KKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEK 141
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY+ +GGL KQ++E++E IELP+KHPELFE +GI PKGV+LYGPPG GKTL+A+A
Sbjct: 142 VPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARA 201
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + FIRV G+ELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ R++ +
Sbjct: 202 VAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGS 261
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
GG+ EV RT+++LL ++DGF+ N+K+I ATNR DILDPALLRPGR DR IE P P
Sbjct: 262 GGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSV 321
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
R EIL++H+R+M L + ++LR +AE G SGAD+K + TEAGM+A+RERR +VTQED
Sbjct: 322 AARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQED 381
Query: 373 FLKAVDKVLGNERK 386
F AV KV+ ++
Sbjct: 382 FELAVGKVMNKNQE 395
>emb|CAA47023.1| (X66400) sug1 [Saccharomyces cerevisiae] >gi|1195528|gb|AAB35417.1|
26S protease subunit S8=SUG1 homolog [human,
erythrocytes, Peptide, 405 aa]
Length = 405
Score = 354 bits (898), Expect = 1e-96
Identities = 177/374 (47%), Positives = 263/374 (69%), Gaps = 8/374 (2%)
Query: 21 YLKRRIRQLELQVRM-------LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +++I++ EL++R LEA + L ++ ++ E+ L++P ++ G VI+++ D
Sbjct: 22 YFEQKIQETELKIRSKTENGRRLEAQRNALNDKVRFIKDELRLLQEPGSYVGEVIKIVSD 81
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ +V+ +++V +A I L+ RV L + + ++L + DP V V +
Sbjct: 82 KKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEK 141
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY+ +GGL KQ++E++E IELP+KHPELFE +GI PKGV+LYGPPG GKTL+A+A
Sbjct: 142 VPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARA 201
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + FIRV G+ELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ R++ +
Sbjct: 202 VAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGS 261
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
GG+ EV RT+++LL ++DGF+ N+K+I ATNR DILDPALLRPGR DR IE P P
Sbjct: 262 GGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSV 321
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
R EIL++H+R+M L + ++LR +AE G SGAD+K + TEAGM+A+RERR +VTQED
Sbjct: 322 AARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQED 381
Query: 373 FLKAVDKVLGNERK 386
F AV KV+ ++
Sbjct: 382 FELAVGKVMNKNQE 395
>gb|AAF91246.1|AF227502_1 (AF227502) proteasome regulatory ATPase subunit 4 [Trypanosoma
brucei]
Length = 399
Score = 352 bits (893), Expect = 5e-96
Identities = 182/368 (49%), Positives = 258/368 (69%), Gaps = 5/368 (1%)
Query: 22 LKRRIRQLELQVRMLEADK--ERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQ 79
+ + IR+ E + R+ E K E EREL R+ ++S L F G ++ +D++R IVQ
Sbjct: 22 IAKTIRRNESRARVREVAKAMEASERELMRVVDQLSALMSIGHFVGEILHKVDEERFIVQ 81
Query: 80 NYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERP-NVT 138
+ +G R +V I+ +KL+ G RVAL+ T+ I+ +LP DP V +V+E N++
Sbjct: 82 SVSGARHLVGYKKSIKPEKLKIGTRVALEITTLTIVRVLPREVDPQVYNMQVMENEKNIS 141
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
+ +IGGL++Q++++RE +ELPL +PELF VGI PPKGVLLYGPPG GKTL+AKA+A V
Sbjct: 142 FQEIGGLQEQMRQMREVVELPLTNPELFVRVGISPPKGVLLYGPPGTGKTLLAKAIASNV 201
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
+A F+++V S +V KYIGE AR++ E+F A++ P IIFIDE+DAIG KR+ E + +R
Sbjct: 202 DAAFLKIVASSIVDKYIGESARVLREMFAFARDHEPCIIFIDEVDAIGGKRI-EGSSSDR 260
Query: 259 EVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
EV RTLM+LL +MDGF+ G VKVI ATNRPD LDPAL+RPGR DR IE+ LP+ GRL+
Sbjct: 261 EVQRTLMELLHQMDGFEKLGKVKVIMATNRPDTLDPALMRPGRLDRKIEIGLPNEAGRLD 320
Query: 319 ILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAV 377
+LK+H ++ K ++D I +++EG +GADL+ + TEAGMFA+R R YV EDF KA
Sbjct: 321 VLKIHASKITKQGDIDYDSIVKLSEGFNGADLRNVCTEAGMFALRAGRDYVINEDFNKAT 380
Query: 378 DKVLGNER 385
KV +++
Sbjct: 381 RKVADSKK 388
>gi|6320197 (putative) 26S protease subunit; Rpt2p [Saccharomyces cerevisiae]
>gi|730904|sp|P40327|PRS4_YEAST 26S PROTEASE REGULATORY
SUBUNIT 4 HOMOLOG (TAT-BINDING HOMOLOG 5)
>gi|626989|pir||S46613 26S proteasome regulatory
particle chain RPT2 - yeast (Saccharomyces cerevisiae)
>gi|531758|emb|CAA56957.1| (X81070) probable regulatory
subunit of 26S proteasome; homologue to S4 subunit of
human 26S proteasome [Saccharomyces cerevisiae]
>gi|683690|emb|CAA88352.1| (Z48432) homolog to S4
subunit of human 26S proteasome (X81070) [Saccharomyces
cerevisiae] >gi|1430967|emb|CAA98563.1| (Z74055) ORF
YDL007w [Saccharomyces cerevisiae]
Length = 437
Score = 351 bits (891), Expect = 8e-96
Identities = 167/342 (48%), Positives = 248/342 (71%), Gaps = 1/342 (0%)
Query: 44 ERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGA 103
E++ + ++ +R P GT+ E++DDD AIV + P + V I +++++ L PG
Sbjct: 86 EKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGC 145
Query: 104 RVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHP 163
V L +TM+I+ +L DP V ++ + P +Y+DIGGL+ Q+QE++E++ELPL HP
Sbjct: 146 SVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHP 205
Query: 164 ELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVH 223
EL+EE+GI PPKGV+LYG PG GKTL+AKA+A++ +ATF+R+VGSEL++KY+G+G RL
Sbjct: 206 ELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCR 265
Query: 224 ELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVI 283
++F++A E AP+I+FIDEIDAIG KR D +GGERE+ RT+++LL ++DGFD RG+VKVI
Sbjct: 266 QIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVI 325
Query: 284 AATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITE 342
ATN+ + LDPAL+RPGR DR I PD + +IL +HT +M L ++V+L + +
Sbjct: 326 MATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKD 385
Query: 343 GASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNE 384
SGAD++A+ TEAG+ A+RERR VT EDF +A ++V+ N+
Sbjct: 386 DLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNK 427
>gb|AAF08387.1|AF145306_1 (AF145306) 26S proteasome regulatory complex subunit p48A
[Drosophila melanogaster] >gi|7292602|gb|AAF48001.1|
(AE003485) Rpt3 gene product [Drosophila melanogaster]
Length = 413
Score = 351 bits (890), Expect = 1e-95
Identities = 178/363 (49%), Positives = 245/363 (67%), Gaps = 3/363 (0%)
Query: 16 DDYITY--LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
D Y+ Y L++ + +E+Q ++ ++ L++E + E+ R++ P G +E +D
Sbjct: 34 DLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPLVIGQFLEAVDQ 93
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ IV + G + VRI I+R+ L+P A VAL + + A++++LP D ++ + E
Sbjct: 94 NTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSISMLQPDE 153
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
+P+V+Y DIGG+ Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA
Sbjct: 154 KPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKA 213
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH A+FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D
Sbjct: 214 VAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQ 273
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
TG +REV R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD
Sbjct: 274 TGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDR 333
Query: 314 EGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
+ + T +M L ++VDL + SGAD+ AI EAGM A+RE R V +D
Sbjct: 334 RQKRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKD 393
Query: 373 FLK 375
F K
Sbjct: 394 FEK 396
>gb|AAA97498.1| (L17040) ATPase [Saccharomyces cerevisiae]
Length = 437
Score = 351 bits (890), Expect = 1e-95
Identities = 167/342 (48%), Positives = 248/342 (71%), Gaps = 1/342 (0%)
Query: 44 ERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGA 103
E++ + ++ +R P GT+ E++DDD AIV + P + V I +++++ L PG
Sbjct: 86 EKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGC 145
Query: 104 RVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHP 163
V L +TM+I+ +L DP V ++ + P +Y+DIGGL+ Q+QE++E++ELPL HP
Sbjct: 146 SVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHP 205
Query: 164 ELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVH 223
EL+EE+GI PPKGV+LYG PG GKTL+AKA+A++ +ATF+R+VGSEL++KY+G+G RL
Sbjct: 206 ELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCR 265
Query: 224 ELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVI 283
++F++A E AP+I+FIDEIDAIG KR D +GGERE+ RT+++LL ++DGFD RG+VKVI
Sbjct: 266 QIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVI 325
Query: 284 AATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITE 342
ATN+ + LDPAL+RPGR DR I PD + +IL +HT +M L ++V+L + +
Sbjct: 326 MATNKIETLDPALIRPGRIDRNILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKD 385
Query: 343 GASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNE 384
SGAD++A+ TEAG+ A+RERR VT EDF +A ++V+ N+
Sbjct: 386 DLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNK 427
>sp|P46507|PRS6_MANSE 26S PROTEASE REGULATORY SUBUNIT 6B (ATPASE MS73)
>gi|559486|emb|CAA86294.1| (Z38135) DEAD-box ATPase
[Manduca sexta]
Length = 415
Score = 350 bits (888), Expect = 2e-95
Identities = 179/370 (48%), Positives = 244/370 (65%), Gaps = 2/370 (0%)
Query: 7 DEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGT 66
DE++ + Y Y L+R + LE+Q ++ ++ L++E + E+ R++ P G
Sbjct: 30 DELESEDLYTKY-KKLQRMLEFLEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPLVIGQ 88
Query: 67 VIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTV 126
+E +D + IV + G + VRI I+R+ L+P A VAL + + A++++LP D ++
Sbjct: 89 FLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSI 148
Query: 127 LGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCG 186
+ E+P+V Y+DIGG+ Q QE+REA+ELPL H EL+ ++GI+PP+GVL+YGPPGCG
Sbjct: 149 SMLQADEKPDVQYSDIGGMDTQKQEIREAVELPLTHVELYRQIGIEPPRGVLMYGPPGCG 208
Query: 187 KTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIG 246
KT++A A+AH A FIRVVGSE V+KY+GEG R+V ++F LAKE +P IIFIDEIDAI
Sbjct: 209 KTMLANAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENSPAIIFIDEIDAIA 268
Query: 247 AKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLI 306
KR D TG +REV R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR I
Sbjct: 269 TKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKI 328
Query: 307 EVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERR 365
E PLPD + I T +M L + VDL + SGAD+ AI EAGM A+RE R
Sbjct: 329 EFPLPDRRQKRLIFSTITAKMNLSEEVDLEEFVARPDRVSGADINAICQEAGMNAVRENR 388
Query: 366 TYVTQEDFLK 375
V +DF K
Sbjct: 389 YIVLPKDFEK 398
>gi|11434084 similar to proteasome (prosome, macropain) 26S subunit, ATPase, 6
(H. sapiens) [Homo sapiens]
>gi|1709804|sp|P49719|PRSX_SPETR 26S PROTEASE REGULATORY
SUBUNIT S10B (P44) (CONSERVED ATPASE DOMAIN PROTEIN 44)
>gi|7435740|pir||JC5349 26S proteosome CADp44 -
Spermophilus tridecemlineatus >gi|1045497|gb|AAB40354.1|
(U36395) conserved ATPase domain protein 44
[Spermophilus tridecemlineatus]
>gi|2213932|gb|AAB61616.1| (AF006305) 26S proteasome
regulatory subunit [Homo sapiens]
Length = 389
Score = 350 bits (888), Expect = 2e-95
Identities = 176/368 (47%), Positives = 250/368 (67%), Gaps = 3/368 (0%)
Query: 21 YLKRRIRQLELQVRMLEADKE--RLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIV 78
Y K+ + E+ R+ E ++ L ++ + +++ L+ G V++ L +++ IV
Sbjct: 12 YRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIV 71
Query: 79 QNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVT 138
+ NGPR+VV +++ KL+PG RVALD T+ I+ LP DP V + NV+
Sbjct: 72 KATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVS 131
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
Y++IGGL +Q++ELRE IELPL +PELF+ VGI PPKG LLYGPPG GKTL+A+A+A ++
Sbjct: 132 YSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQL 191
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
+ F++VV S +V KYIGE ARL+ E+F A++ P IIF+DEIDAIG +R E T +R
Sbjct: 192 DCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADR 251
Query: 259 EVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
E+ RTLM+LL +MDGFD VK+I ATNRPD LDPALLRPGR DR I + LP+ + RL+
Sbjct: 252 EIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLD 311
Query: 319 ILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAV 377
ILK+H + K +D I ++++G +GADL+ + TEAGMFAIR +V QEDF+KAV
Sbjct: 312 ILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAV 371
Query: 378 DKVLGNER 385
KV +++
Sbjct: 372 RKVADSKK 379
>emb|CAA11285.1| (AJ223384) 26S proteasome regulatory ATPase subunit 10b (S10b)
[Manduca sexta]
Length = 396
Score = 349 bits (887), Expect = 2e-95
Identities = 176/372 (47%), Positives = 253/372 (67%), Gaps = 2/372 (0%)
Query: 15 YDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDD 74
+ DY L +++E +++ + + L ++ + +++ L+ G V++ L ++
Sbjct: 16 FQDYRKKLMEH-KEVESRLKAMRDQLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEE 74
Query: 75 RAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIER 134
+ IV+ NGPR+VV ++++KL+ G RVALD T+ I+ LP DP V +
Sbjct: 75 KFIVKATNGPRYVVGCRRQLDKNKLKGGTRVALDMTTLTIMRHLPREVDPLVYNMSHEDP 134
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
+VTY IGGL++Q+++LRE IELPL +PELF VGI PPKG LLYGPPG GKTL+A+A+
Sbjct: 135 GDVTYAAIGGLQEQIRQLREVIELPLLNPELFVRVGITPPKGCLLYGPPGTGKTLLARAV 194
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
A +++A F++VV S +V KYIGE ARL+ E+F A++ P IIF+DEIDAIG +R E T
Sbjct: 195 ASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGT 254
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
+RE+ RTLM+LL +MDGFD G VK+I ATNRPD LDPALLRPGR DR IE+PLP+ +
Sbjct: 255 SADREIQRTLMELLNQMDGFDSLGQVKIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQ 314
Query: 315 GRLEILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDF 373
RLEILK+H + K +D + ++++ +GADL+ + TEAG+FAIR R Y+ QED
Sbjct: 315 ARLEILKIHAAPIAKHGEMDYEAVVKLSDTFNGADLRNVCTEAGLFAIRAEREYIIQEDL 374
Query: 374 LKAVDKVLGNER 385
+KAV KV N++
Sbjct: 375 MKAVRKVADNKK 386
>pir||T48743 probable 26S ATP/ubiquitin-dependent proteinase chain S4 [imported]
- Neurospora crassa >gi|7635793|emb|CAB88559.1|
(AL353819) probable 26S ATP/ubiquitin-dependent
proteinase chain S4 [Neurospora crassa]
Length = 471
Score = 349 bits (887), Expect = 2e-95
Identities = 171/337 (50%), Positives = 245/337 (71%), Gaps = 1/337 (0%)
Query: 51 RSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQR 110
RS + +R P G + E++DDD AIV + +GP + V I ++++D L PGA V L +
Sbjct: 127 RSRVDDMRGSPMGVGVLEELIDDDHAIVSSTSGPEYYVSIMSFVDKDLLEPGASVLLHHK 186
Query: 111 TMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVG 170
+++I+ +L DP V ++ + P +Y DIGGL++Q+QE+RE++ELPL HPEL+EE+G
Sbjct: 187 SVSIVGVLTDDTDPAVSVMKLDKAPTESYADIGGLEQQIQEVRESVELPLLHPELYEEMG 246
Query: 171 IDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAK 230
I PPKGV+LYG PG GKTL+AKA+A++ +ATF+R+VGSEL++KY+G+G RLV +LF++A
Sbjct: 247 IKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLVRQLFQVAA 306
Query: 231 EKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPD 290
E AP+I+FIDEIDAIG KR D T+GGERE+ RT+++LL ++DGFD RG+VKVI ATN+ +
Sbjct: 307 ENAPSIVFIDEIDAIGTKRYDSTSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIE 366
Query: 291 ILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADL 349
LDPAL+RPGR DR I PD + +I +HT +M L ++VDL + SGAD+
Sbjct: 367 SLDPALIRPGRIDRKILFENPDQNTKRKIFTLHTSKMSLNEDVDLEEFIAQKDDLSGADI 426
Query: 350 KAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
KAI +EAG+ A+RERR V DF A ++VL +++
Sbjct: 427 KAICSEAGLMALRERRMRVQMADFRAARERVLRTKQE 463
>sp|Q63570|PRS6_RAT 26S PROTEASE REGULATORY SUBUNIT 6B (TAT-BINDING PROTEIN-7) (TBP-7)
>gi|1395186|dbj|BAA09340.1| (D50695) proteasomal ATPase
(Tat-binding protein7) [Rattus norvegicus]
Length = 418
Score = 349 bits (885), Expect = 4e-95
Identities = 177/366 (48%), Positives = 245/366 (66%), Gaps = 1/366 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ + LE+Q ++ +++ L++E + E+ R++ P G +E +D + AIV +
Sbjct: 47 LQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGST 106
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VRI I+R+ L+P A VAL + + A++++LP D +++ ++P+V Y D
Sbjct: 107 TGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYAD 166
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG+ Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA+AH A
Sbjct: 167 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D TG +REV
Sbjct: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQ 286
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + I
Sbjct: 287 RILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFS 346
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
T +M L + VDL + SGAD+ +I E+GM A+RE R V +DF KA V
Sbjct: 347 TITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTV 406
Query: 381 LGNERK 386
+ + +
Sbjct: 407 IKKDEQ 412
>gi|5729991 proteasome (prosome, macropain) 26S subunit, ATPase, 4 [Homo
sapiens] >gi|2791680|gb|AAC26843.1| (AF038965) 26S
proteasome ATPase subunit [Homo sapiens]
>gi|4096275|gb|AAC99817.1| (U27515) MIP224 [Homo
sapiens] >gi|5080757|gb|AAD39267.1|AC007842_2 (AC007842)
ATPase homolog [Homo sapiens]; MIP22; TAT-BINDING
PROTEIN-7; TBP-7; 26S PROTEASE REGULATORY SUBUNIT 6B
Length = 418
Score = 349 bits (885), Expect = 4e-95
Identities = 177/366 (48%), Positives = 245/366 (66%), Gaps = 1/366 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ + LE+Q ++ +++ L++E + E+ R++ P G +E +D + AIV +
Sbjct: 47 LQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGST 106
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VRI I+R+ L+P A VAL + + A++++LP D +++ ++P+V Y D
Sbjct: 107 TGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYAD 166
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG+ Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA+AH A
Sbjct: 167 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D TG +REV
Sbjct: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQ 286
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + I
Sbjct: 287 RILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFS 346
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
T +M L + VDL + SGAD+ +I E+GM A+RE R V +DF KA V
Sbjct: 347 TITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTV 406
Query: 381 LGNERK 386
+ + +
Sbjct: 407 IKKDEQ 412
>sp|P43686|PRS6_HUMAN 26S PROTEASE REGULATORY SUBUNIT 6B (TAT-BINDING PROTEIN-7) (TBP-7)
Length = 418
Score = 348 bits (884), Expect = 5e-95
Identities = 177/366 (48%), Positives = 245/366 (66%), Gaps = 1/366 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ + LE+Q ++ +++ L++E + E+ R++ P G +E +D + AIV +
Sbjct: 47 LQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGST 106
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VRI I+R+ L+P A VAL + + A++++LP D +++ ++P+V Y D
Sbjct: 107 TGSNYYVRILSAIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYAD 166
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG+ Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA+AH A
Sbjct: 167 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D TG +REV
Sbjct: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQ 286
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + I
Sbjct: 287 RILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFS 346
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
T +M L + VDL + SGAD+ +I E+GM A+RE R V +DF KA V
Sbjct: 347 TITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTV 406
Query: 381 LGNERK 386
+ + +
Sbjct: 407 IKKDEQ 412
>sp|O17071|PRSX_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT S10B
>gi|7499759|pir||T32268 hypothetical protein F23F1.8 -
Caenorhabditis elegans >gi|2394434|gb|AAB70326.1|
(AF024493) strong similarity to the AAA family of
ATPases [Caenorhabditis elegans]
Length = 398
Score = 348 bits (884), Expect = 5e-95
Identities = 170/362 (46%), Positives = 251/362 (68%), Gaps = 2/362 (0%)
Query: 27 RQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRF 86
R +E +++ L + + ++ + +++ L+ G V++ L +++ IV+ NGPR+
Sbjct: 29 RDIEQKLKDLRKKESEMTKQFDKSENDIKSLQSVGQIVGEVLKQLSEEKFIVKATNGPRY 88
Query: 87 VVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLK 146
VV I +++L+ G RV+LD T+ I+ LP DP V + N++Y+D+GGL
Sbjct: 89 VVGCRRSINKEELKQGTRVSLDMTTLTIMRQLPREVDPLVYKMSHEDPGNISYSDVGGLA 148
Query: 147 KQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV 206
+Q++ELRE +ELPL +PELF+ VGI PPKG LL+GPPG GKTL+A+A+A +++ F++VV
Sbjct: 149 EQIRELREVVELPLINPELFKRVGITPPKGCLLFGPPGTGKTLLARAVASQLDCNFLKVV 208
Query: 207 GSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ 266
S +V KYIGE AR++ E+F A++ P I+F+DEIDAIG +R E T +RE+ RTLM+
Sbjct: 209 SSAIVDKYIGESARMIREMFNYARDHQPCIVFMDEIDAIGGRRFSEGTSADREIQRTLME 268
Query: 267 LLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRR 326
LL ++DGFD G VKVI ATNRPD LDPALLRPGR DR IE+ LP+ + RLEILK+H+ +
Sbjct: 269 LLNQLDGFDSLGKVKVIMATNRPDTLDPALLRPGRLDRKIEIGLPNEQSRLEILKIHSNK 328
Query: 327 M-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNER 385
+ K +D + ++++G S ADL+ + TEAGMFAIR R +V EDF+KAV KV G+ +
Sbjct: 329 ITKHGEIDFEAVVKLSDGFSAADLRNVCTEAGMFAIRAEREFVIDEDFMKAVRKV-GDAK 387
Query: 386 KL 387
+L
Sbjct: 388 RL 389
>sp|P46502|PRS6_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT 6B
>gi|529215|gb|AAA20608.1| (U12965) similar to
CDC48/PAS1/SEC18 family; highest similarity to 26S
protease subunit 4, member of eukaryotic ATPase family
[Caenorhabditis elegans]
Length = 414
Score = 348 bits (883), Expect = 7e-95
Identities = 179/369 (48%), Positives = 246/369 (66%), Gaps = 3/369 (0%)
Query: 16 DDYI--TYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
DDYI T L+R++ L++ ++ + LE+EL + E+ R++ P G +E +D
Sbjct: 35 DDYIKLTTLERQLAHLQVMEDYIKLETRNLEKELLHAQEEVKRIQSVPLVIGQFLEAVDQ 94
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ AIV + G + VR+ ++R+ L+PG VAL + + A++++LP D ++ E
Sbjct: 95 NHAIVGSTTGSNYYVRVLSILDRELLKPGCSVALHKYSNALVDVLPPEADSSIQMLRPDE 154
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
+P+++Y DIGGL Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA
Sbjct: 155 KPDISYGDIGGLDMQKQEVREAVELPLTHGELYQQIGIDPPRGVLMYGPPGCGKTMLAKA 214
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+A A+FIRVVGSE V+KY+GEG R+V ++F LAKE +P+IIFIDEIDAI KR D
Sbjct: 215 VAANTAASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENSPSIIFIDEIDAIATKRFDAQ 274
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
TG +REV R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD
Sbjct: 275 TGADREVQRILLELLNQMDGFDQSTNVKVIMATNRQDTLDPALLRPGRLDRKIEFPLPDR 334
Query: 314 EGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
+ + RM L +VDL + SGAD+ +I EAGM A+RE R V +D
Sbjct: 335 RQKRLVFSTVCSRMNLSDDVDLEDWVARPDKISGADINSICQEAGMQAVRENRYVVLTKD 394
Query: 373 FLKAVDKVL 381
KA V+
Sbjct: 395 LEKAYKNVV 403
>gi|4506215 proteasome (prosome, macropain) 26S subunit, ATPase, 6; p42 [Homo
sapiens] >gi|2492522|sp|Q92524|PRSX_HUMAN 26S PROTEASE
REGULATORY SUBUNIT S10B (PROTEASOME SUBUNIT P42)
>gi|7435741|pir||S71316 multicatalytic endopeptidase
complex (EC 3.4.99.46) p42 chain - human
>gi|1526426|dbj|BAA11338.1| (D78275) proteasome subunit
p42 [Homo sapiens]
Length = 389
Score = 348 bits (883), Expect = 7e-95
Identities = 175/368 (47%), Positives = 249/368 (67%), Gaps = 3/368 (0%)
Query: 21 YLKRRIRQLELQVRMLEADKE--RLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIV 78
Y K+ + E+ R+ E ++ L ++ + +++ L+ G V++ L +++ IV
Sbjct: 12 YRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIV 71
Query: 79 QNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVT 138
+ NGPR+VV +++ KL+PG RVALD T+ I+ LP DP V + NV+
Sbjct: 72 KATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVS 131
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
Y++IGGL +Q++ELRE IELPL +PELF+ VGI PPKG LLYGPPG GKTL+A+A+A ++
Sbjct: 132 YSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQL 191
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
+ F++VV S +V KYIGE ARL+ E+F A++ P IIF+DEIDAIG +R E T +R
Sbjct: 192 DCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADR 251
Query: 259 EVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
E+ RTLM+LL +MDGFD VK+ ATNRPD LDPALLRPGR DR I + LP+ + RL+
Sbjct: 252 EIQRTLMELLNQMDGFDTLHRVKMTMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLD 311
Query: 319 ILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAV 377
ILK+H + K +D I ++++G +GADL+ + TEAGMFAIR +V QEDF+KAV
Sbjct: 312 ILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAV 371
Query: 378 DKVLGNER 385
KV +++
Sbjct: 372 RKVADSKK 379
>gi|6324833 ATPase; component of the 26S proteasome cap subunit; Rpt4p
[Saccharomyces cerevisiae]
>gi|2506090|sp|P53549|SUG2_YEAST PROBABLE 26S PROTEASE
SUBUNIT SUG2 (PROTEASOMAL CAP SUBUNIT)
>gi|2133163|pir||S67156 26S proteasome regulatory
particle chain RPT4 - yeast (Saccharomyces cerevisiae)
>gi|1420585|emb|CAA99481.1| (Z75167) ORF YOR259c
[Saccharomyces cerevisiae] >gi|1931623|gb|AAB51594.1|
(U93262) proteasome cap subunit [Saccharomyces
cerevisiae]
Length = 437
Score = 347 bits (881), Expect = 1e-94
Identities = 174/370 (47%), Positives = 242/370 (65%), Gaps = 15/370 (4%)
Query: 12 HENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVL 71
H YDD + ++ IR LE + + +++ L+ G V++ L
Sbjct: 67 HRRYDDQLKQRRQNIRDLE--------------KLYDKTENDIKALQSIGQLIGEVMKEL 112
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+++ IV+ +GPR++V + ++R KL+ G RV LD T+ I+ +LP DP V
Sbjct: 113 SEEKYIVKASSGPRYIVGVRNSVDRSKLKKGVRVTLDITTLTIMRILPRETDPLVYNMTS 172
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+ +T++ IGGL +Q++ELRE IELPLK+PE+F+ VGI PPKGVLLYGPPG GKTL+A
Sbjct: 173 FEQGEITFDGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLA 232
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
KA+A + A FI S +V KYIGE AR++ E+F AKE P IIF+DE+DAIG +R
Sbjct: 233 KAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFS 292
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
E T +RE+ RTLM+LL +MDGFD G K+I ATNRPD LDPALLRPGR DR +E+PLP
Sbjct: 293 EGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLP 352
Query: 312 DFEGRLEILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
+ GRLEI K+HT ++ K D ++++G +GAD++ ATEAG FAIR+ R ++
Sbjct: 353 NEAGRLEIFKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRDHINP 412
Query: 371 EDFLKAVDKV 380
+D +KAV KV
Sbjct: 413 DDLMKAVRKV 422
>gb|AAC32612.1| (AF020736) ATPase homolog [Homo sapiens]
Length = 418
Score = 347 bits (880), Expect = 2e-94
Identities = 176/366 (48%), Positives = 245/366 (66%), Gaps = 1/366 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ + LE+Q ++ +++ L++E + E+ R++ P G +E +D + AIV +
Sbjct: 47 LQQELEFLEVQEEYIKDEQKNLKKEFFHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGST 106
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VRI I+R+ L+P A VAL + + A++++LP D +++ ++P+V Y D
Sbjct: 107 TGSSYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSGQKPDVMYAD 166
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG+ Q QE+REA+ELP+ H EL++++GIDPP+GVL+YGPPGCGKT++AKA+AH A
Sbjct: 167 IGGMDIQKQEVREAVELPVTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D TG +REV
Sbjct: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQ 286
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + I
Sbjct: 287 RILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFS 346
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
T +M L + VDL + SGAD+ +I E+GM A+RE R V +DF KA V
Sbjct: 347 TITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTV 406
Query: 381 LGNERK 386
+ + +
Sbjct: 407 IKKDEQ 412
>gb|AAF49987.1| (AE003543) CG7257 gene product [Drosophila melanogaster]
Length = 398
Score = 346 bits (879), Expect = 2e-94
Identities = 173/360 (48%), Positives = 244/360 (67%), Gaps = 1/360 (0%)
Query: 27 RQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRF 86
R++E +++ L + + E + ++ L+ G +++ L D IV+ NGPR+
Sbjct: 29 REIESKLKALRDKYKVVNAEYEKSEDDLKALQSVGQMVGEILKQLTPDNFIVKASNGPRY 88
Query: 87 VVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLK 146
VV I ++KL+PG RVALD T+ I+ LP DP V + NV Y +IGGL
Sbjct: 89 VVGCRRQINKEKLKPGTRVALDVTTLTIMRYLPREVDPLVYNMTHEDPGNVNYAEIGGLG 148
Query: 147 KQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV 206
+Q++ELRE IELPL +P++F VGI PPKG LLYGPPG GKTL+A+A+A +++A F++VV
Sbjct: 149 QQIRELREVIELPLLNPDIFLRVGISPPKGCLLYGPPGTGKTLLARAIASQMDANFLKVV 208
Query: 207 GSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ 266
S +V KYIGE ARL+ E+F A++ P IIF+DEIDAIG +R E T +RE+ RTLM+
Sbjct: 209 SSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLME 268
Query: 267 LLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRR 326
LL +MDGFD G VK+I ATNRPD LDPALLRPGR DR +E+PLP+ R++ILK+H
Sbjct: 269 LLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLEIPLPNEVARMDILKIHAEP 328
Query: 327 M-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNER 385
+ K +D + ++++ +GADL+ I TEAG+FA+R R +V QEDF+KAV K+ N++
Sbjct: 329 LNKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQEDFMKAVRKIADNKK 388
>sp|P54778|PRS6_SOLTU 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG >gi|7435738|pir||T07110
vacuolar proton-ATPase chain E - potato
>gi|1155334|gb|AAB67835.1| (U43398) POTATP1 [Solanum
tuberosum]
Length = 413
Score = 346 bits (878), Expect = 3e-94
Identities = 177/355 (49%), Positives = 238/355 (66%), Gaps = 1/355 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L+R++ +E+Q ++ + + L RE R + E+ R++ P G +E++D + AIV +
Sbjct: 42 LQRQLEFIEIQEEYVKDELKNLRREHLRAQEEVKRIQSVPLVIGQFMEMIDQNNAIVGST 101
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VRI I R+ L+P A V LD+ + A++++LP D ++ E+P+VTYND
Sbjct: 102 TGSNYYVRILSTINRELLKPSASVGLDRHSNALVDVLPPEADSSISLLSQSEKPDVTYND 161
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG Q QE+REA+ELPL H EL++++GIDPP+GVLLYGPPG GKT++AKA+AH A
Sbjct: 162 IGGCDIQKQEIREAVELPLTHHELYKQIGIDPPRGVLLYGPPGTGKTMLAKAVAHHTTAA 221
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDE+DAI R D TG +REV
Sbjct: 222 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEVDAIATARFDAQTGADREVQ 281
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R LM+LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + + +
Sbjct: 282 RILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFQ 341
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
V T +M L VDL + S A++ AI EAGM A+R+ R + +DF K
Sbjct: 342 VCTAKMNLGDEVDLEDYVSRPDKISAAEITAICQEAGMHAVRKNRYVILPKDFEK 396
>gb|AAA85134.1| (U43720) Sug2p [Saccharomyces cerevisiae]
Length = 437
Score = 346 bits (877), Expect = 4e-94
Identities = 174/370 (47%), Positives = 241/370 (65%), Gaps = 15/370 (4%)
Query: 12 HENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVL 71
H YDD + ++ IR LE + + +++ L+ G V++ L
Sbjct: 67 HRRYDDQLKQRRQNIRDLE--------------KLYDKTENDIKALQSIGQLIGEVMKEL 112
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+++ IV+ +GPR++V + +R KL+ G RV LD T+ I+ +LP DP V
Sbjct: 113 SEEKYIVKPSSGPRYIVGVRNSADRSKLKKGVRVTLDITTLTIMRILPRETDPLVYNMTS 172
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+ +T++ IGGL +Q++ELRE IELPLK+PE+F+ VGI PPKGVLLYGPPG GKTL+A
Sbjct: 173 FEQGEITFDGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLA 232
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
KA+A + A FI S +V KYIGE AR++ E+F AKE P IIF+DE+DAIG +R
Sbjct: 233 KAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFS 292
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
E T +RE+ RTLM+LL +MDGFD G K+I ATNRPD LDPALLRPGR DR +E+PLP
Sbjct: 293 EGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLP 352
Query: 312 DFEGRLEILKVHTRRM-KLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
+ GRLEI K+HT ++ K D ++++G +GAD++ ATEAG FAIR+ R ++
Sbjct: 353 NEAGRLEIFKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRDHINP 412
Query: 371 EDFLKAVDKV 380
+D +KAV KV
Sbjct: 413 DDLMKAVRKV 422
>gb|AAB24841.1| Tat binding protein 7, TBP-7=transcriptional activator [human,
Peptide, 458 aa]
Length = 458
Score = 345 bits (876), Expect = 5e-94
Identities = 175/355 (49%), Positives = 240/355 (67%), Gaps = 1/355 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ + LE+Q ++ +++ L++E + E+ R++ P G +E +D + AIV +
Sbjct: 47 LQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGST 106
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VRI I+R+ L+P A VAL + + A++++LP D +++ ++P+V Y D
Sbjct: 107 TGSNYYVRILSAIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYAD 166
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG+ Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA+AH A
Sbjct: 167 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D TG +REV
Sbjct: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQ 286
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + I
Sbjct: 287 RILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFS 346
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
T +M L + VDL + SGAD+ +I E+GM A+RE R V +DF K
Sbjct: 347 TITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 401
>gb|AAG19042.1| (AE005003) ATP-dependent 26S proteinase regulatory subunit 4
homolog; PrrIV2 [Halobacterium sp. NRC-1]
Length = 368
Score = 344 bits (874), Expect = 8e-94
Identities = 180/350 (51%), Positives = 248/350 (70%), Gaps = 5/350 (1%)
Query: 34 RMLEADKE--RLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIA 91
R+L+A+ E + +++L RL E +L+Q P F TV E+ D+ I Q+ N + +
Sbjct: 4 RLLDANAENNKYQQKLERLSHENKKLKQSPLFIATVQELTDEGAVIKQHGNNQEALTEVT 63
Query: 92 PWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQE 151
+ R L PG+RVA++ +++++ L D EV + P+V Y DIGGL QL+E
Sbjct: 64 DEL-RATLEPGSRVAVNN-SLSVVRQLDDEADVRARVMEVDDSPDVGYEDIGGLDDQLRE 121
Query: 152 LREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELV 211
+RE +ELP+K P LFE VGI+PP GVLL+GPPG GKTLMAKA+A + +A+FI++ GSELV
Sbjct: 122 VRETVELPMKDPGLFETVGINPPSGVLLHGPPGTGKTLMAKAVASQTDASFIKMAGSELV 181
Query: 212 RKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEM 271
K+IGEGA+LV +LF++A++ P ++FIDEIDAI +KR D T G+ EV RT+MQLL+EM
Sbjct: 182 HKFIGEGAKLVRDLFQVARDHEPAVVFIDEIDAIASKRTDSKTSGDAEVQRTMMQLLSEM 241
Query: 272 DGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-K 330
DGFD RG++++IAATNR D+LD A+LRPGRFDRLIEVP P+ GR +I ++HTR M +
Sbjct: 242 DGFDERGDIRIIAATNRFDMLDRAILRPGRFDRLIEVPHPNVGGREKIFRIHTRAMNVAD 301
Query: 331 NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
+VD +A T SGAD+KAI TEAGMFAIR+ RT V +DF A +K+
Sbjct: 302 SVDFGELAADTGDLSGADVKAICTEAGMFAIRDDRTEVRMQDFQSAREKL 351
>gi|7110701 proteasome (prosome, macropain) 26S subunit, ATPase, 4; CAR
interacing protein 21 [Mus musculus]
>gi|1709797|sp|P54775|PRS6_MOUSE 26S PROTEASE REGULATORY
SUBUNIT 6B (CIP21) (MIP224) (MB67 INTERACTING PROTEIN)
>gi|1196528|gb|AAA88243.1| (L76223) ATPase [Mus
musculus] >gi|10697240|dbj|BAB16348.1| (AB040869)
proteasomal ATPase [Mus musculus]
Length = 418
Score = 343 bits (870), Expect = 2e-93
Identities = 174/366 (47%), Positives = 243/366 (65%), Gaps = 1/366 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ + LE+Q ++ +++ L++E + E+ R++ P G +E +D + AIV +
Sbjct: 47 LQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVAST 106
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VR+ I+R+ L+P A VAL + + A++++LP + D +++ ++P+V Y D
Sbjct: 107 TGSNYYVRMVSTIDRELLKPNASVALHKHSNALVDVLPPAADSSIMMLTSDQKPDVMYAD 166
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG+ Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA+AH A
Sbjct: 167 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D TG +REV
Sbjct: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQ 286
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + I
Sbjct: 287 RILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFS 346
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
T +M L + VDL + SGAD+ +I GM A+RE V +DF KA V
Sbjct: 347 TITSKMNLSEEVDLEDYVARPDKISGADINSICQARGMLAVRETAYIVLAKDFEKAYKTV 406
Query: 381 LGNERK 386
+ + +
Sbjct: 407 IKKDEQ 412
>gb|AAF35993.1|AC005836_5 (AC005836) 26S Protease Regulatory Subunit [Leishmania major]
Length = 396
Score = 342 bits (869), Expect = 3e-93
Identities = 177/366 (48%), Positives = 256/366 (69%), Gaps = 5/366 (1%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
++R + Q L + + D + +REL ++ +++ L + G V++ +D++R IV++
Sbjct: 23 VERNVTQARL--KKVNDDVKLQQRELDKVEDQVNALLSIGHYVGEVLKRVDEERFIVKSI 80
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERP-NVTYN 140
+G R +V I+ +KL+ GARVAL+ T I+++LP DP V + + +V++
Sbjct: 81 SGARHLVGYRKSIKPEKLKFGARVALEITTFTIVKVLPREVDPQVYSMQYMSSDKDVSFQ 140
Query: 141 DIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
DIGGL+ Q++++RE IELPL +PELF VGI PPKGVLLYGPPG GKTL+AKA+A V+A
Sbjct: 141 DIGGLQPQMRQMREVIELPLTNPELFVRVGIAPPKGVLLYGPPGTGKTLLAKAIAANVDA 200
Query: 201 TFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREV 260
F+++V S +V KYIGE AR++ E+F A+E P IIFIDE+DAIG+KR+ E + +RE+
Sbjct: 201 AFLKIVASSIVDKYIGESARVIREMFAYAREHEPCIIFIDEVDAIGSKRI-EGSSSDREI 259
Query: 261 NRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEIL 320
RTLM+LL +MDGFD G VKVI ATNRPD LD AL+RPGR DR IE+PLP+ GRL++L
Sbjct: 260 QRTLMELLNQMDGFDKLGKVKVIMATNRPDTLDAALMRPGRLDRKIEIPLPNEAGRLDVL 319
Query: 321 KVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDK 379
++H+ ++ K ++D + +++EG +GADL+ + TEAGMFAIR R YV DF KAV K
Sbjct: 320 RIHSAKITKKGDIDFESVVKLSEGFNGADLRNVCTEAGMFAIRAGRDYVENSDFNKAVRK 379
Query: 380 VLGNER 385
V +R
Sbjct: 380 VADMKR 385
>gb|AAF22523.1|AF123392_1 (AF123392) 26S proteasome AAA-ATPase subunit RPT3 [Arabidopsis
thaliana] >gi|8777330|dbj|BAA96920.1| (AB019228) 26S
proteasome AAA-ATPase subunit RPT3 [Arabidopsis
thaliana]
Length = 408
Score = 342 bits (868), Expect = 4e-93
Identities = 178/376 (47%), Positives = 249/376 (65%), Gaps = 5/376 (1%)
Query: 1 MNIMSGDEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP 60
M++ + DE E+ + L+R++ ++Q ++ +++ L+REL R + E+ R++
Sbjct: 20 MDLSTADE----EDLYGRLKSLERQLEFTDIQEEYVKDEQKNLKRELLRAQEEVKRIQSV 75
Query: 61 PAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS 120
P G +E++D + IV + G + VRI I R+ L+P A VAL + + A++++LP
Sbjct: 76 PLVIGQFMEMVDQNNGIVGSTTGSNYYVRILSTINRELLKPSASVALHRHSNALVDVLPP 135
Query: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
D ++ E+P+V+YNDIGG Q QE+REA+ELPL H EL++++GIDPP+GVLLY
Sbjct: 136 EADSSISLLSQSEKPDVSYNDIGGCDIQKQEIREAVELPLTHHELYKQIGIDPPRGVLLY 195
Query: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
GPPG GKT++AKA+A+ A FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFID
Sbjct: 196 GPPGTGKTMLAKAVANHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFID 255
Query: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
E+DAI R D TG +REV R LM+LL +MDGFD NVKVI ATNR D LDPALLRPG
Sbjct: 256 EVDAIATARFDAQTGADREVQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPG 315
Query: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMF 359
R DR IE PLPD + + +V T +M L + VDL + S A++ AI EAGM
Sbjct: 316 RLDRKIEFPLPDRRQKRLVFQVCTSKMNLSDEVDLEDYVSRPDKISAAEIAAICQEAGMH 375
Query: 360 AIRERRTYVTQEDFLK 375
A+R+ R + +DF K
Sbjct: 376 AVRKNRYVILPKDFEK 391
>gb|AAF91245.1|AF227501_1 (AF227501) proteasome regulatory ATPase subunit 3 [Trypanosoma
brucei]
Length = 403
Score = 342 bits (867), Expect = 5e-93
Identities = 175/368 (47%), Positives = 242/368 (65%), Gaps = 4/368 (1%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L R I+ LEL+ + + + L++E S + E+ R++ P GT +E ++ R IV
Sbjct: 31 LVRSIQNLELKTMICKTETHHLQKEESAAKQEVKRIQAVPLVLGTFVEAVEAGRGIVGGS 90
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
+ + VRI ++++KL+PGA V L + + + +++LP+ D V +RPNVTY+D
Sbjct: 91 SSSNYYVRILSTLDKEKLKPGASVGLHKGSNSCVQILPNEIDSAVHVLRKEDRPNVTYSD 150
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
+GGL Q QE+REA+ELPL H L++++GIDPP+GVLLYGPPG GKT++ KA+AH NA
Sbjct: 151 VGGLDMQKQEIREAVELPLTHASLYDQIGIDPPRGVLLYGPPGTGKTMLVKAVAHHTNAA 210
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FI VVGSE V+KY+GEG R V ++F LA+E AP IIFIDE+D+I KR D TG +REV
Sbjct: 211 FISVVGSEFVQKYLGEGPRKVRDVFRLARENAPAIIFIDEVDSIATKRFDAQTGADREVQ 270
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LLA+MDGFD NVKVI ATNR D LDPA+LRPGR DR IE P PD + + +
Sbjct: 271 RVLIELLAQMDGFDQTTNVKVIMATNRWDTLDPAILRPGRLDRKIEFPYPDRRQKRLVFQ 330
Query: 322 VHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDF---LKAV 377
V T RM L VDL E +GAD+++I EAGM A+R+ R V +D + V
Sbjct: 331 VCTSRMNLSPEVDLEEFVTRPERLTGADIQSICHEAGMLAVRKNRYVVLPKDIESAYRTV 390
Query: 378 DKVLGNER 385
+ G+E+
Sbjct: 391 TRKTGDEQ 398
>pir||S51042 tat-binding protein homolog - malaria parasite (Plasmodium
falciparum)
Length = 435
Score = 341 bits (866), Expect = 7e-93
Identities = 178/380 (46%), Positives = 259/380 (67%), Gaps = 6/380 (1%)
Query: 3 IMSGDEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPA 62
+ SG + + ++Y + + ++++ + LEA + L + L E+ L + +
Sbjct: 46 VQSGIKRYYELKIEEYESIINKKLQNK----KRLEAQRNELNARVRELCDEIQYLLEAAS 101
Query: 63 FAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSK 122
+ G +++ + ++ +V+ ++VV IA I P RVAL + + ++LPS
Sbjct: 102 YVGEIVKPMGKNKVLVKINPEGKYVVDIARHINISHCTPNTRVALYNDSYKLHKILPSKV 161
Query: 123 DPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGP 182
DP V +V + P+ TY +GGL +Q++E++E IELP+KHPE+FE +GI PKGVLLYGP
Sbjct: 162 DPLVSLMKVEKVPDSTYEMVGGLDQQVKEVKEVIELPVKHPEIFESLGISQPKGVLLYGP 221
Query: 183 PGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEI 242
PG GKTL+A+A+AH + TFIRV GSELV+KYIGEG+R+V ELF +A+E AP+IIF+DEI
Sbjct: 222 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEI 281
Query: 243 DAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRF 302
D+IG++R+ E G+ EV RT+M+LL ++DGF+ N+KVI TNR DILD ALLRPGR
Sbjct: 282 DSIGSQRI-EGEHGDSEVQRTMMELLNQLDGFESTQNIKVIMCTNRIDILDEALLRPGRI 340
Query: 303 DRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAI 361
DR IE P P+ E R+EILK+H+R++ L + +D+ IA SGA++KA+ TEAGMFA+
Sbjct: 341 DRKIEFPNPNVEARMEILKIHSRKINLMRGIDMLKIATHMNNCSGAEVKAVCTEAGMFAL 400
Query: 362 RERRTYVTQEDFLKAVDKVL 381
RERR +VTQEDF AV KV+
Sbjct: 401 RERRVHVTQEDFEMAVAKVM 420
>emb|CAB63651.1| (AJ251819) 26S proteasome subunit 8 [Fagus sylvatica]
Length = 418
Score = 341 bits (866), Expect = 7e-93
Identities = 188/376 (50%), Positives = 260/376 (69%), Gaps = 12/376 (3%)
Query: 21 YLKRRIRQLELQVRM-------LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y + I + +LQVR LEA + + LR E+ L++P ++ G V++V+
Sbjct: 31 YYLQHIHEHQLQVRQKTHNLNRLEAQRNEFNSRVRMLREELQLLQEPGSYVGEVVKVMGK 90
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
++ +V+ ++ ++VV I I+ K+ P RVAL + + +LPS DP V +V +
Sbjct: 91 NKVLVKVHSEGKYVVDIDKNIDITKITPSTRVALRNDSYVLHLILPSKVDPLVNLMKVEK 150
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELF-EEVGIDPPKGVLLYGPPGCGKTLMAK 192
P+ TY+ IGGL +Q++E++E IELP+KHPELF E +GI PKGVLLYGPPG GKTL+A+
Sbjct: 151 VPDSTYDMIGGLDQQIKEIKEVIELPIKHPELFLESLGIAQPKGVLLYGPPGTGKTLLAR 210
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+AH + TFIRV GSELV+KYIGEG+R+V ELF +A+E AP+IIF+DEID+IG+ RM+
Sbjct: 211 AVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMES 270
Query: 253 TTG-GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+G G+ EV +++LL ++DGF+ +KV+ TNR DILD ALLRPGR DR IE P P
Sbjct: 271 GSGNGDSEVQDHMLELLNQLDGFESIKQIKVLMRTNRIDILDQALLRPGRIDRKIEFPNP 330
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAI-RERRT-YV 368
+ E R +ILK+H+RRM L + +DL+ IAE GASGA+LKA+ TEAGMFA+ ERR V
Sbjct: 331 NRESRFDILKIHSRRMNLMRGIDLKKIAEKMNGASGAELKAVCTEAGMFALTAERRVRLV 390
Query: 369 TQEDFLKAVDKVLGNE 384
TQEDF AV KV+ E
Sbjct: 391 TQEDFEMAVAKVMKKE 406
>sp|P34123|PRS6_DICDI 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG (TAT-BINDING PROTEIN
HOMOLOG 2) >gi|422298|pir||JN0611 probable transcription
factor DdTBP2 - slime mold (Dictyostelium discoideum)
>gi|290055|gb|AAA33253.1| (L16578) HIV1 TAT-binding
protein [Dictyostelium discoideum]
Length = 403
Score = 340 bits (864), Expect = 1e-92
Identities = 179/371 (48%), Positives = 245/371 (65%), Gaps = 3/371 (0%)
Query: 8 EVQFHENYDDY--ITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAG 65
E H D Y + L+ ++ +Q ++ + + L+REL + E+ R+R P G
Sbjct: 16 EASHHREADLYQKMKSLESKLDFFNIQEEYIKYEYKNLKRELLHAQEEVKRIRSVPLLIG 75
Query: 66 TVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPT 125
++E++D + IVQ+ +G VRI I+R+ L+P A VAL + + A+++ LP D +
Sbjct: 76 QLLEMVDSNTGIVQSTSGSTLCVRILSTIDRELLKPSASVALQRHSNALVDTLPPESDSS 135
Query: 126 VLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGC 185
+ E+P+ +Y+DIGG Q QE+REA+ELPL H L++++GIDPP+GVLLYGPPG
Sbjct: 136 IHLLGADEKPSESYSDIGGGDIQKQEMREAVELPLTHHNLYKQIGIDPPRGVLLYGPPGT 195
Query: 186 GKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAI 245
GKT++AKA+AH +A FIRVVGSE V+KY+GEG RLV ++F LA+E +P IIFIDEIDAI
Sbjct: 196 GKTMLAKAVAHHTSAAFIRVVGSEFVQKYLGEGPRLVRDVFRLARENSPAIIFIDEIDAI 255
Query: 246 GAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRL 305
KR D TG +REV R LM+LL +MDGFD NVKVI ATNR D LDPALLRPGR DR
Sbjct: 256 ATKRFDAQTGADREVQRILMELLNQMDGFDVSVNVKVIMATNRQDTLDPALLRPGRLDRK 315
Query: 306 IEVPLPDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRER 364
IE PLPD + I +V T +M L + VDL + SGA++++I EAGM AIR+
Sbjct: 316 IEFPLPDRRQKRLIFQVITSKMNLSDEVDLEDYVSRPDKLSGAEIQSICQEAGMHAIRKN 375
Query: 365 RTYVTQEDFLK 375
R + +DF K
Sbjct: 376 RYVILPKDFEK 386
>dbj|BAB17624.1| (AB033535) 26S proteasome regulatory particle triple-A ATPase
subunit1 [Oryza sativa]
Length = 426
Score = 340 bits (864), Expect = 1e-92
Identities = 165/352 (46%), Positives = 241/352 (67%), Gaps = 10/352 (2%)
Query: 36 LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIE 95
L +DK+ ++ E + +++ P DD + ++ +FVV + +
Sbjct: 73 LVSDKQMMQEEQPLQVARCTKIISPNT---------DDAKYVINVKQIAKFVVGLGDKVS 123
Query: 96 RDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREA 155
+ G RV +D+ I LP DP+V V E+P+VTYND+GG K+Q++++RE
Sbjct: 124 PTDIEEGMRVGVDRNKYQIQIPLPPKIDPSVTMMTVEEKPDVTYNDVGGCKEQIEKMREV 183
Query: 156 IELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYI 215
+ELP+ HPE F ++GIDPPKGVL YGPPG GKTL+A+A+A+ +A FIRV+GSELV+KY+
Sbjct: 184 VELPMLHPEKFVKLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYV 243
Query: 216 GEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
GEGAR+V ELF++A+ K I+F DE+DAIG R D+ GG+ EV RT+++++ ++DGFD
Sbjct: 244 GEGARMVRELFQMARSKKACIVFFDEVDAIGGARFDDGVGGDNEVQRTMLEIVNQLDGFD 303
Query: 276 PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDL 334
RGN+KV+ ATNRPD LDPALLRPGR DR +E LPD EGR +I K+HTR M +++
Sbjct: 304 ARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLEGRTQIFKIHTRTMNCERDIRF 363
Query: 335 RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
++A + ++GAD++++ TEAGM+AIR RR VT++DFL AV+KV+ +K
Sbjct: 364 ELLARLCPNSTGADIRSVCTEAGMYAIRARRKTVTEKDFLDAVNKVIKGYQK 415
>gi|4506209 proteasome (prosome, macropain) 26S subunit, ATPase, 2; Proteasome
26S subunit, ATPase, 2 [Homo sapiens]
>gi|547930|sp|P35998|PRS7_HUMAN 26S PROTEASE REGULATORY
SUBUNIT 7 (MSS1 PROTEIN) >gi|107102|pir||S24353
proteasome 26S subunit MSS1 - human
>gi|219931|dbj|BAA01868.1| (D11094) MSS1 protein [Homo
sapiens] >gi|228886|prf||1813280A tat-mediated
transactivation modulator [Homo sapiens]
Length = 433
Score = 340 bits (862), Expect = 2e-92
Identities = 162/316 (51%), Positives = 228/316 (71%), Gaps = 1/316 (0%)
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+D + I+ +FVV ++ + + G RV +D+ I LP DPTV +V
Sbjct: 107 EDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQV 166
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+P+VTY+D+GG K+Q+++LRE +E PL HPE F +GI+PPKGVLL+GPPG GKTL A
Sbjct: 167 EEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCA 226
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A+A+ +A FIRV+GSELV+KY+GEGAR+V ELFE+A+ K +IF DEIDAIG R D
Sbjct: 227 RAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFD 286
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRPD LDPAL+RPGR DR IE LP
Sbjct: 287 DGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLP 346
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D EGR I K+H R M + +++ ++A + ++GA+++++ TEAGMFAIR RR T+
Sbjct: 347 DLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATE 406
Query: 371 EDFLKAVDKVLGNERK 386
+DFL+AV+KV+ + K
Sbjct: 407 KDFLEAVNKVIKSYAK 422
>sp|P46472|PRS7_XENLA 26S PROTEASE REGULATORY SUBUNIT 7 (MSS1 PROTEIN)
>gi|1079305|pir||S53709 MSS1 protein homolog - African
clawed frog >gi|695772|emb|CAA56438.1| (X80157) xMSS1
[Xenopus laevis] >gi|1095500|prf||2109230A MSS1-like
protein [Xenopus laevis]
Length = 433
Score = 340 bits (862), Expect = 2e-92
Identities = 162/316 (51%), Positives = 228/316 (71%), Gaps = 1/316 (0%)
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+D + I+ +FVV ++ + + G RV +D+ I LP DPTV +V
Sbjct: 107 EDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQV 166
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+P+VTY+D+GG K+Q+++LRE +E PL HPE F +GI+PPKGVLL+GPPG GKTL A
Sbjct: 167 EEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCA 226
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A+A+ +A FIRV+GSELV+KY+GEGAR+V ELFE+A+ K +IF DEIDAIG R D
Sbjct: 227 RAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFD 286
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRPD LDPAL+RPGR DR IE LP
Sbjct: 287 DGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLP 346
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D EGR I K+H R M + +++ ++A + ++GA+++++ TEAGMFAIR RR T+
Sbjct: 347 DLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATE 406
Query: 371 EDFLKAVDKVLGNERK 386
+DFL+AV+KV+ + K
Sbjct: 407 KDFLEAVNKVIKSYAK 422
>sp|Q41365|PRS7_SPIOL 26S PROTEASE REGULATORY SUBUNIT 7 (26S PROTEASOME SUBUNIT 7)
>gi|7435732|pir||T09104 26S proteasome ATPase chain -
spinach >gi|1395191|dbj|BAA13021.1| (D86121) 26S
proteasome ATPase subunit [Spinacia oleracea]
Length = 426
Score = 339 bits (860), Expect = 4e-92
Identities = 164/352 (46%), Positives = 241/352 (67%), Gaps = 10/352 (2%)
Query: 36 LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIE 95
L +DK+ ++ E + +++ P +D + ++ +FVV + +
Sbjct: 73 LVSDKQMMQEEQPLQVARCTKIINPNT---------EDAKYVINVKQIAKFVVGLGDKVS 123
Query: 96 RDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREA 155
+ G RV +D+ I LP DP+V V E+P+VTYND+GG K+Q++++RE
Sbjct: 124 PTDIEEGMRVGVDRNKYQIQIPLPPKIDPSVTMMTVEEKPDVTYNDVGGCKEQIEKMREV 183
Query: 156 IELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYI 215
+ELP+ HPE F ++GIDPPKGVL YGPPG GKTL+A+A+A+ +A FIRV+GSELV+KY+
Sbjct: 184 VELPMLHPEKFVKLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYV 243
Query: 216 GEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
GEGAR+V ELF++A+ K I+F DE+DAIG R D+ GG+ EV RT+++++ ++DGFD
Sbjct: 244 GEGARMVRELFQMARSKKACIVFFDEVDAIGGARFDDGVGGDNEVQRTMLEIVNQLDGFD 303
Query: 276 PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDL 334
RGN+KV+ ATNRPD LDPALLRPGR DR +E LPD EGR +I K+HTR M +++
Sbjct: 304 ARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLEGRTQIFKIHTRTMNCERDIRF 363
Query: 335 RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
++A + ++GAD++++ TEAGM+AIR RR VT++DFL AV+KV+ +K
Sbjct: 364 ELLARLCPNSTGADIRSVCTEAGMYAIRARRKTVTEKDFLDAVNKVIKGYQK 415
>gb|AAF54440.1| (AE003684) CG9475 gene product [Drosophila melanogaster]
Length = 421
Score = 339 bits (860), Expect = 4e-92
Identities = 175/404 (43%), Positives = 256/404 (63%), Gaps = 29/404 (7%)
Query: 1 MNIMSGDEVQFHEN----------YDDYITY--LKRRIRQLELQVRMLEADKERLERELS 48
M ++ + QFHE +D Y+ Y L+ + +++Q ++ ++ L++E
Sbjct: 1 MRLLKEEIAQFHEQSLEKYDGLDPHDLYVLYKKLQMELELIQVQEDYIKEEQRNLKKEFI 60
Query: 49 RLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALD 108
+ E+ R++ P G +E +D++ IV + G + VR+ I+R++L+P + V L
Sbjct: 61 HAQEEVKRIKAVPLVIGQFLEAVDENNGIVASTTGSNYYVRVLSTIDREQLKPSSSVGLH 120
Query: 109 QRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEE 168
+++ +++L+P D T+ E+P+++Y+DIGGL Q QE+REA+ELPL H +L+++
Sbjct: 121 KQSNCLVDLVPPEADSTISMLSPDEKPDISYSDIGGLDIQKQEIREAVELPLTHAQLYKQ 180
Query: 169 VG----------------IDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVR 212
+G IDPP+GVLL+GPPGCGKT++AKA+AH A+FIRVVGSE V+
Sbjct: 181 IGGYSQYQKTISTNSLPGIDPPRGVLLFGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQ 240
Query: 213 KYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMD 272
KY+GEG R+V +LF LAK+ +P+IIFIDEIDAI KR D TG +REV R L++LL +MD
Sbjct: 241 KYLGEGPRMVRDLFRLAKQNSPSIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMD 300
Query: 273 GFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KN 331
GFD N+KVI ATNR D LDPALLRPGR DR IE+PLPD + + T +M + ++
Sbjct: 301 GFDETTNIKVIMATNRADTLDPALLRPGRLDRKIELPLPDRRQKRLVFTTITSKMNVGED 360
Query: 332 VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
VDL I + S AD+ AI EAGM A+RE R V +DF K
Sbjct: 361 VDLEDIIARPDKISNADINAICQEAGMHAVRENRYVVNAKDFEK 404
>gb|AAB33476.1| Tat-binding protein alpha, DdTBP alpha=Tat-binding protein 1
homolog/26S protease subunit homolog [Dictyostelium
discoideum, Peptide, 439 aa]
Length = 439
Score = 339 bits (859), Expect = 5e-92
Identities = 175/371 (47%), Positives = 253/371 (68%), Gaps = 8/371 (2%)
Query: 13 ENYDDYITYLKRRIRQLEL-QVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVL 71
E DY+ + ++ +L Q ++ E KE+ + + + LR P G + EV+
Sbjct: 62 ERIKDYLLMEQEFLQNYDLNQPKVDENSKEQADEHI------IEELRGDPLTVGNLEEVI 115
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
DD+ AIV + GP VRI ++++ KL GA V L+ +T++++ ++ DP V +V
Sbjct: 116 DDNHAIVSSTVGPEHYVRIMSFVDKSKLYLGATVLLNNKTLSVVGVIDGEVDPMVNVIKV 175
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ P +Y+DIGGL+ Q+QE++EAIELPL HPEL++E+GI PPKGV+LYG PG GKTL+A
Sbjct: 176 EKAPTESYSDIGGLEAQVQEMKEAIELPLTHPELYKEIGIKPPKGVILYGEPGTGKTLLA 235
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
KA+A++ TF RVVGSE ++KY+G+G RLV EL+ +A E AP+I+FIDEID++ KR D
Sbjct: 236 KAVANQYLYTFKRVVGSEKIQKYLGDGPRLVRELYRVADECAPSIVFIDEIDSVFTKRYD 295
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+GGERE+ RT+++LL ++DGFD R + K I ATNR + LDPA +RPGR DR IE PLP
Sbjct: 296 SQSGGEREIQRTMLELLNQLDGFDARTDCKCIMATNRIETLDPARIRPGRIDRKIEFPLP 355
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D + + +I K+HT +M L ++V+L+ + GAD+KAI TE+G+ A+RERR VT
Sbjct: 356 DIKTKRKIFKLHTAKMNLSEDVNLKEFVMSKDDLCGADIKAICTESGLLALRERRMRVTH 415
Query: 371 EDFLKAVDKVL 381
DF KA +KVL
Sbjct: 416 TDFKKAKEKVL 426
>gi|6322704 putative ATPase, 26S protease subunit component; Rpt1p
[Saccharomyces cerevisiae]
>gi|464862|sp|P33299|PRS7_YEAST 26S PROTEASE REGULATORY
SUBUNIT 7 HOMOLOG (CIM5 PROTEIN) (TAT-BINDING HOMOLOG 3)
>gi|422126|pir||S34354 26S proteasome regulatory
particle chain RPT1 - yeast (Saccharomyces cerevisiae)
>gi|313882|emb|CAA51973.1| (X73571) 26S proteasome
subunit Rpt1 [Saccharomyces cerevisiae]
>gi|410510|emb|CAA80470.1| (Z22817) putative ATPase
[Saccharomyces cerevisiae] >gi|486249|emb|CAA81986.1|
(Z28145) ORF YKL145w [Saccharomyces cerevisiae]
>gi|738777|prf||2001430A 26S protease [Saccharomyces
cerevisiae]
Length = 467
Score = 338 bits (858), Expect = 6e-92
Identities = 162/316 (51%), Positives = 226/316 (71%), Gaps = 1/316 (0%)
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+D + ++ +FVV + + + G RV +D+ I LP DP+V V
Sbjct: 141 EDAKYVINLKQIAKFVVGLGERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTV 200
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+P+VTY+D+GG K Q+++LRE +ELPL PE F +GIDPPKG+LLYGPPG GKTL A
Sbjct: 201 EEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCA 260
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A+A+ +ATFIRV+GSELV+KY+GEGAR+V ELFE+A+ K IIF DEIDA+G R D
Sbjct: 261 RAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFD 320
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRP+ LDPALLRPGR DR +E LP
Sbjct: 321 DGAGGDNEVQRTMLELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLP 380
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D EGR I ++H++ M + + + +I+ + ++GA+L+++ TEAGMFAIR RR T+
Sbjct: 381 DLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATE 440
Query: 371 EDFLKAVDKVLGNERK 386
+DFLKAVDKV+ +K
Sbjct: 441 KDFLKAVDKVISGYKK 456
>gb|AAF91244.1|AF227500_1 (AF227500) proteasome regulatory ATPase subunit 2 [Trypanosoma
brucei]
Length = 437
Score = 338 bits (858), Expect = 6e-92
Identities = 176/354 (49%), Positives = 242/354 (67%), Gaps = 6/354 (1%)
Query: 28 QLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFV 87
Q + Q + E E ELS++ + LR P GT+ EV+DD AIV G +
Sbjct: 75 QWDAQENLEEGAMSHYEAELSKVDA----LRGMPLEVGTLEEVIDDTHAIVSTA-GSEYY 129
Query: 88 VRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKK 147
V + +++++KL G V L R ++ LL S+ DP V +V + P TY DIGGL+
Sbjct: 130 VAMLSFVDKEKLELGCSVLLHDRYHNVVGLLESNTDPLVSVMKVDKAPQETYADIGGLED 189
Query: 148 QLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVG 207
Q+QE++EA+E PL HPELF+EVG+ PPKGV++YG PG GKTL+AKA+A++ +ATF+RVVG
Sbjct: 190 QIQEIKEAVEFPLSHPELFDEVGVKPPKGVIVYGVPGTGKTLLAKAVANQTSATFLRVVG 249
Query: 208 SELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQL 267
SEL++KY GEG +LV ELF +A+E +P+I+FIDEIDAIG KR D +GG +EV RT+++L
Sbjct: 250 SELIQKYSGEGPKLVRELFRVAEENSPSIVFIDEIDAIGTKRYDTDSGGAKEVQRTMLEL 309
Query: 268 LAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRM 327
L ++DGFD +VKVI ATNR + LDPAL+RPGR DR IE P PD + + I ++HT RM
Sbjct: 310 LTQLDGFDSCNDVKVIMATNRIETLDPALIRPGRIDRKIEFPFPDEKTKKMIFEIHTSRM 369
Query: 328 KL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKV 380
L ++VDL + SGAD++AI TEAG+ A+R+RR V Q DF+K + V
Sbjct: 370 SLAEDVDLSEFIPAKDEMSGADIQAICTEAGLLALRDRRMKVCQSDFVKGKENV 423
>gb|AAF08388.1|AF145307_1 (AF145307) 26S proteasome regulatory complex subunit p48B
[Drosophila melanogaster] >gi|7304183|gb|AAF59219.1|
(AE003840) Rpt1 gene product [Drosophila melanogaster]
Length = 433
Score = 337 bits (856), Expect = 1e-91
Identities = 170/383 (44%), Positives = 254/383 (65%), Gaps = 6/383 (1%)
Query: 10 QFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLR-QPPAFAGTVI 68
Q+H++ +++ ++Q+ + E+D L L ++ L+ + P
Sbjct: 40 QYHKSIKSIEEDIQKAVKQVNELTGIKESDTGLAPPALWDLAADKQILQNEQPLQVARCT 99
Query: 69 EVL----DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDP 124
+++ DD + I+ +FVV +A + + G RV +D+ I LP DP
Sbjct: 100 KIINADSDDPKYIINVKQFAKFVVDLADSVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDP 159
Query: 125 TVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPG 184
TV +V ++P+VTY+D+GG K+Q+++LRE +E PL HPE F +GI+PPKGVLL+GPPG
Sbjct: 160 TVTMMQVEDKPDVTYSDVGGCKEQIEKLREVVETPLLHPEKFVNLGIEPPKGVLLFGPPG 219
Query: 185 CGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDA 244
GKTL A+A+A+ +A FIRV+GSELV+KY+GEGAR+V ELFE+A+ K +IF DEIDA
Sbjct: 220 TGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARSKKACLIFFDEIDA 279
Query: 245 IGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDR 304
IG R D+ GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRPD LDPAL+RPGR DR
Sbjct: 280 IGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDR 339
Query: 305 LIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRE 363
+E LPD +GR I K+H R M + +++ ++A + ++GA+++++ TEAGMFAIR
Sbjct: 340 KVEFGLPDQDGRSHIFKIHARSMSVERDIRFDLLARLCPNSTGAEIRSVCTEAGMFAIRA 399
Query: 364 RRTYVTQEDFLKAVDKVLGNERK 386
RR T++DFL+AV KV+ + K
Sbjct: 400 RRKVATEKDFLEAVKKVIKSYAK 422
>sp|Q63347|PRS7_RAT 26S PROTEASE REGULATORY SUBUNIT 7 (MSS1 PROTEIN)
>gi|1395179|dbj|BAA09339.1| (D50694) proteasomal ATPase
(MSS1) [Rattus norvegicus]
Length = 433
Score = 337 bits (855), Expect = 1e-91
Identities = 161/316 (50%), Positives = 227/316 (70%), Gaps = 1/316 (0%)
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+D + I+ +FVV ++ + + G RV +D+ I LP DPTV +V
Sbjct: 107 EDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQV 166
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+P+VTY+D+GG K+Q+++LRE +E PL HPE F +GI+PPKGVLL+GPPG GKTL A
Sbjct: 167 EEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCA 226
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A+A+ +A FI V+GSELV+KY+GEGAR+V ELFE+A+ K +IF DEIDAIG R D
Sbjct: 227 RAVANRTDACFIPVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFD 286
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRPD LDPAL+RPGR DR IE LP
Sbjct: 287 DGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLP 346
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D EGR I K+H R M + +++ ++A + ++GA+++++ TEAGMFAIR RR T+
Sbjct: 347 DLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATE 406
Query: 371 EDFLKAVDKVLGNERK 386
+DFL+AV+KV+ + K
Sbjct: 407 KDFLEAVNKVIKSYAK 422
>sp|O64982|PRS7_PRUPE 26S PROTEASE REGULATORY SUBUNIT 7 (26S PROTEASOME SUBUNIT 7)
>gi|3172331|gb|AAC18523.1| (AF041258) 26S proteasome
subunit 7 [Prunus persica]
Length = 425
Score = 337 bits (855), Expect = 1e-91
Identities = 163/352 (46%), Positives = 241/352 (68%), Gaps = 10/352 (2%)
Query: 36 LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIE 95
L +DK+ ++ E + +++ P + +D + ++ +FVV + +
Sbjct: 72 LVSDKQMMQEEQPLQVARCTKIINPNS---------EDAKYVINVKQIAKFVVGLGDKVS 122
Query: 96 RDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREA 155
+ G RV +D+ I LP DP+V V E+P+VTYND+GG K+Q++++RE
Sbjct: 123 PTDIEEGMRVGVDRNKYQIQIPLPPKIDPSVTMMTVEEKPDVTYNDVGGCKEQIEKMREV 182
Query: 156 IELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYI 215
+ELP+ HPE F ++GIDPPKGVL YGPPG GKTL+A+A+A+ +A FIRV+GSELV+KY+
Sbjct: 183 VELPMLHPEKFVKLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYV 242
Query: 216 GEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
GEGAR+V ELF++A+ K I+F DE+DAIG R D+ GG+ EV RT+++++ ++DGFD
Sbjct: 243 GEGARMVRELFQMARSKKACIVFFDEVDAIGGARFDDGVGGDNEVQRTMLEIVNQLDGFD 302
Query: 276 PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDL 334
RGN+KV+ ATNRPD LDPALLRPGR DR +E LPD E R +I K+HTR M +++
Sbjct: 303 ARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLESRTQIFKIHTRTMNCERDIRF 362
Query: 335 RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
++A + ++GAD++++ TEAGM+AIR RR VT++DFL AV+KV+ +K
Sbjct: 363 ELLARLCPNSTGADIRSVCTEAGMYAIRARRKTVTEKDFLDAVNKVIKGYQK 414
>sp|P46471|PRS7_MOUSE 26S PROTEASE REGULATORY SUBUNIT 7 (MSS1 PROTEIN)
Length = 433
Score = 337 bits (854), Expect = 2e-91
Identities = 160/316 (50%), Positives = 227/316 (71%), Gaps = 1/316 (0%)
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+D + I+ +FVV ++ + + G RV +D+ I LP DPTV +V
Sbjct: 107 EDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQV 166
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+P+VTY+D+GG K+Q+++LRE +E PL HPE +GI+PPKGVLL+GPPG GKTL A
Sbjct: 167 EEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERLVNLGIEPPKGVLLFGPPGTGKTLCA 226
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A+A+ +A FIRV+GSELV+KY+GEGAR+V ELFE+A+ K +IF DE+DAIG R D
Sbjct: 227 RAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEMDAIGGARFD 286
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRPD LDPAL+RPGR DR IE LP
Sbjct: 287 DGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLP 346
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D EGR I K+H R M + +++ ++A + ++GA+++++ TEAGMFAIR RR T+
Sbjct: 347 DLEGRTHIFKIHARSMSVERDIGFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATE 406
Query: 371 EDFLKAVDKVLGNERK 386
+DFL+AV+KV+ + K
Sbjct: 407 KDFLEAVNKVIKSYAK 422
>gb|AAF02852.1|AC009324_1 (AC009324) 26S proteasome ATPase subunit [Arabidopsis thaliana]
>gi|10645345|gb|AAG21465.1|AC024260_8 (AC024260) 26S
proteasome ATPase subunit; 3861-6264 [Arabidopsis
thaliana]
Length = 426
Score = 337 bits (854), Expect = 2e-91
Identities = 163/352 (46%), Positives = 240/352 (67%), Gaps = 10/352 (2%)
Query: 36 LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIE 95
L +DK+ ++ E + +++ P +D + ++ +FVV + +
Sbjct: 73 LVSDKQMMQEEQPLQVARCTKIISPNT---------EDAKYVINVKQIAKFVVGLGDKVS 123
Query: 96 RDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREA 155
+ G RV +D+ I LP DP+V V E+P+VTYND+GG K+Q++++RE
Sbjct: 124 PTDIEEGMRVGVDRNKYQIQIPLPPKIDPSVTMMTVEEKPDVTYNDVGGCKEQIEKMREV 183
Query: 156 IELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYI 215
+ELP+ HPE F ++GIDPPKGVL YGPPG GKTL+A+A+A+ +A FIRV+GSELV+KY+
Sbjct: 184 VELPMLHPEKFVKLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYV 243
Query: 216 GEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
GEGAR+V ELF++A+ K I+F DE+DAIG R D+ GG+ EV RT+++++ ++DGFD
Sbjct: 244 GEGARMVRELFQMARSKKACIVFFDEVDAIGGARFDDGVGGDNEVQRTMLEIVNQLDGFD 303
Query: 276 PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDL 334
RGN+KV+ ATNRPD LDPALLRPGR DR +E LPD E R +I K+HTR M +++
Sbjct: 304 ARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLESRTQIFKIHTRTMNCERDIRF 363
Query: 335 RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
++A + ++GAD++++ TEAGM+AIR RR VT++DFL AV+KV+ +K
Sbjct: 364 ELLARLCPNSTGADIRSVCTEAGMYAIRARRKTVTEKDFLDAVNKVIKGYQK 415
>gb|AAG38539.1|AF309805_4 (AF309805) putative 26S protease regulatory subunit 4 [Pneumocystis
carinii f. sp. carinii]
Length = 437
Score = 337 bits (854), Expect = 2e-91
Identities = 175/381 (45%), Positives = 254/381 (65%), Gaps = 8/381 (2%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSE-MSRLRQPPAFAGTVIEVL 71
E DY+ + + EL L+ D E+ +++ + + L P GT+ E++
Sbjct: 56 ERIKDYLLLEQEFVSNQEL----LKLDSEKRDQKGEEEDDDKLQSLIGSPMGVGTLEEMI 111
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
DDD AIV + GP + V I ++ +D L PG V L + ++I+ +L DP V ++
Sbjct: 112 DDDHAIVSSATGPEYYVSIMSFVNKDLLEPGCSVLLHHKAVSIVGVLSDDIDPMVSVMKL 171
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ P +Y DIGGL+ Q+QE++E +ELPL HPEL+EE+GI PPKGV+LYG PG GKTL+A
Sbjct: 172 DKAPTESYADIGGLESQIQEIKETVELPLTHPELYEEIGIRPPKGVILYGEPGTGKTLLA 231
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
KA+A++ +ATF+R+VGSEL++KY+G+G + V ELF+ A++ +P+I+FIDEIDAIG KR D
Sbjct: 232 KAVANQTSATFLRIVGSELIQKYLGDGPKFVRELFQTAQDNSPSIVFIDEIDAIGTKRYD 291
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
T+ GERE+ RT+++LL ++DGFD RG+VKVI ATNR + LDPAL+RPGR DR I P
Sbjct: 292 STSSGEREIQRTMLELLNQLDGFDDRGDVKVIMATNRINDLDPALIRPGRMDRKILFETP 351
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLK--AIATEAGMFAIRERRTYV 368
D + +I ++HT +M L +V + + SGAD+K AI TEAG+ A+RERR V
Sbjct: 352 DQNTKRKIFQIHTSKMNLGDDVLIEEFITAKDEMSGADVKVIAICTEAGLLALRERRMRV 411
Query: 369 TQEDFLKAVDKVLGNERKLLQ 389
+DF KA + VL ++K +Q
Sbjct: 412 VADDFRKAKEHVLKTKQKNIQ 432
>sp|Q18787|PRS7_CAEEL PROBABLE 26S PROTEASE REGULATORY SUBUNIT 7 >gi|7497832|pir||T20152
hypothetical protein C52E4.4 - Caenorhabditis elegans
>gi|3875191|emb|CAB01414.1| (Z78012) Similarity to Human
26S protease regulatory subunit 7 (SW:PRS7_HUMAN),
contains similarity to Pfam domain: PF00004 (ATPases
associated with various cellular activities (AAA)),
Score=326.4, E-value=1.1e-94, N=1~cDNA EST EMBL:T00856
comes from t>
Length = 435
Score = 336 bits (852), Expect = 3e-91
Identities = 158/310 (50%), Positives = 226/310 (71%), Gaps = 1/310 (0%)
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D R ++ +FVV +A + + G RV +D+ I LP+ DPTV +V
Sbjct: 110 DPRYLINVKQFAKFVVDLADSVAPTDIEEGMRVGVDRNKYQIHLPLPAKIDPTVTMMQVE 169
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+P+VTY+D+GG K Q+++LRE +E PL HPE + +GI+PPKGVLLYGPPG GKTL A+
Sbjct: 170 EKPDVTYSDVGGCKDQIEKLREVVETPLLHPERYVNLGIEPPKGVLLYGPPGTGKTLCAR 229
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A+ +A FIRV+GSELV+KY+GEGAR+V ELFE+A+ K +IF DEIDA+G R D+
Sbjct: 230 AVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAVGGARFDD 289
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRPD LDPAL+RPGR DR +E LPD
Sbjct: 290 GQGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKVEFALPD 349
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR ILK+H ++M + +++ ++A + ++GA+++++ TEAGMFAIR RR T++
Sbjct: 350 LAGRAHILKIHAKQMSVERDIRYDLLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEK 409
Query: 372 DFLKAVDKVL 381
DFL+A++KV+
Sbjct: 410 DFLEAINKVV 419
>gb|AAF91248.1|AF227504_1 (AF227504) proteasome regulatory ATPase subunit 6 [Trypanosoma
brucei]
Length = 408
Score = 336 bits (852), Expect = 3e-91
Identities = 181/377 (48%), Positives = 255/377 (67%), Gaps = 11/377 (2%)
Query: 20 TYLKRRIRQLELQVRML-------EADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
TY ++I++L Q + L EA + L R + L+ E+ L++ + V+ V+
Sbjct: 21 TYFLQKIQELRAQEKRLQDNYMRLEAQRNELNRRVRHLKEEVQLLQESGSIVADVVRVMS 80
Query: 73 DDRAIVQ-NYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+ +V + + + VV + + D L RVAL T AI +LP+ DP V +V
Sbjct: 81 KGKVLVNVSSSQGKLVVDVEKTVNIDDLSRNVRVALRSGTFAIHYILPTKVDPLVSLMKV 140
Query: 132 IERPNV-TYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLM 190
+ TY++IGGL +Q++E++E IEL +KHPELFE +GI PKGVLLYGPPG GKTL+
Sbjct: 141 ENAGSESTYDEIGGLSRQVKEIKEVIELSVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 200
Query: 191 AKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRM 250
A+A+AH + TFIRV G+ELV+KYIGEGARLV ELF +A+E +P+IIF+DEID+IG+ R+
Sbjct: 201 ARAVAHHTDCTFIRVSGAELVQKYIGEGARLVRELFVMAREHSPSIIFMDEIDSIGSTRL 260
Query: 251 DET-TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVP 309
+ T GG+ EV RT+++LL ++DGF+ ++KVI ATNR DILD ALLRPGR DR IE
Sbjct: 261 ENTGRGGDSEVQRTMLELLNQLDGFESTQSIKVIMATNRVDILDEALLRPGRIDRKIEFS 320
Query: 310 LPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYV 368
PD R EILK+++R+M L + ++LR +AE T SGA KA+ TEAGMFA+RERR ++
Sbjct: 321 APDEPARFEILKINSRKMNLTRGINLRTVAEKTNQCSGAAYKAVCTEAGMFALRERRVHI 380
Query: 369 TQEDFLKAVDKVLGNER 385
TQEDF AV K++ ++
Sbjct: 381 TQEDFELAVAKIMHKDQ 397
>sp|P36612|PRS4_SCHPO 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG (MTS2 PROTEIN)
>gi|481780|pir||S39348 26S ATP/ubiquitin-dependent
proteinase chain S4 - fission yeast (Schizosaccharomyces
pombe) >gi|442508|emb|CAA82554.1| (Z29366) mts2 gene
[Schizosaccharomyces pombe] >gi|6066725|emb|CAB58406.1|
(AL121863) 26s protease regulatory subunit 4 homolog
[Schizosaccharomyces pombe] >gi|738776|prf||2001429A
ubiquitin-dependent protease [Schizosaccharomyces pombe]
Length = 448
Score = 335 bits (850), Expect = 5e-91
Identities = 171/348 (49%), Positives = 246/348 (70%), Gaps = 6/348 (1%)
Query: 39 DKERLERELSRLRSEMSR---LRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIE 95
++ERL+ + R + E +R +R P GT+ E++DDD AIV GP + V I +++
Sbjct: 88 NQERLKPQDERTQEERNRVDEIRGTPMSVGTLEEIIDDDHAIVSTA-GPEYYVSIMSFVD 146
Query: 96 RDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREA 155
+D L PG V L + M+I+ LL DP + ++ + P +Y DIGGL+ Q+QE++EA
Sbjct: 147 KDMLEPGCSVLLHHKAMSIVGLLLDDTDPMINVMKLDKAPTESYADIGGLESQIQEIKEA 206
Query: 156 IELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYI 215
+ELPL HPEL+EE+GI PPKGV+LYG PG GKTL+AKA+A++ +ATF+RVVGSEL++KY+
Sbjct: 207 VELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYL 266
Query: 216 GEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
G+G RLV +LF A+E +P+I+FIDEIDAIG KR D +G ERE+ RT+++LL ++DGFD
Sbjct: 267 GDGPRLVRQLFNAAEEHSPSIVFIDEIDAIGTKRYDAQSGAEREIQRTMLELLNQLDGFD 326
Query: 276 -PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVD 333
+ ++KVI ATNR LDPAL+RPGR DR I PD + +I +HT +M L ++V+
Sbjct: 327 TSQRDIKVIMATNRISDLDPALIRPGRIDRKILFENPDEATKRKIFTIHTSKMNLGEDVN 386
Query: 334 LRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVL 381
L + + + SGA++KAI +EAG+ A+RERR V +DF +A +KVL
Sbjct: 387 LEELIQCKDDLSGAEIKAIVSEAGLLALRERRMRVVMDDFRQAREKVL 434
>emb|CAA16915.2| (AL021767) 26s protease regulatory subunit 7 homolog
[Schizosaccharomyces pombe]
Length = 438
Score = 335 bits (850), Expect = 5e-91
Identities = 162/303 (53%), Positives = 221/303 (72%), Gaps = 2/303 (0%)
Query: 85 RFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGG 144
+FVV + + + G RV D+ AI LP DP+V +V E+P+VTY D+GG
Sbjct: 124 KFVVSLGERVSPTDIEEGMRVGCDRNKYAIQLPLPPKIDPSVTMMQVEEKPDVTYGDVGG 183
Query: 145 LKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIR 204
K+Q++ LRE +ELPL PE F ++GIDPPKG++LYGPPG GKTL A+A+A+ +ATFIR
Sbjct: 184 CKEQIERLREVVELPLLSPERFVKLGIDPPKGIMLYGPPGTGKTLCARAVANRTDATFIR 243
Query: 205 VVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTL 264
V+GSELV+KY+GEGAR+V ELFE+A+ K IIF DEIDAIG R D+ GG+ EV RT+
Sbjct: 244 VIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAIGGARFDDGAGGDNEVQRTM 303
Query: 265 MQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHT 324
++L+ ++DGFDPRGN+KV+ ATNRP+ LD AL+RPGR DR +E LPD EGR IL++H
Sbjct: 304 LELITQLDGFDPRGNIKVLFATNRPNTLDEALMRPGRIDRKVEFGLPDLEGRAHILRIHA 363
Query: 325 RRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVL-G 382
+ M + K++ +IA + +GA+L+++ TEAGMFAIR RR T++DFL AV KV+ G
Sbjct: 364 KSMAIDKDIRWELIARLCPSQTGAELRSVCTEAGMFAIRARRRVATEKDFLDAVQKVVKG 423
Query: 383 NER 385
N++
Sbjct: 424 NQK 426
>pir||T39558 26S proteinase regulatory subunit 7 - fission yeast
(Schizosaccharomyces pombe)
Length = 440
Score = 335 bits (850), Expect = 5e-91
Identities = 162/303 (53%), Positives = 221/303 (72%), Gaps = 2/303 (0%)
Query: 85 RFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGG 144
+FVV + + + G RV D+ AI LP DP+V +V E+P+VTY D+GG
Sbjct: 126 KFVVSLGERVSPTDIEEGMRVGCDRNKYAIQLPLPPKIDPSVTMMQVEEKPDVTYGDVGG 185
Query: 145 LKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIR 204
K+Q++ LRE +ELPL PE F ++GIDPPKG++LYGPPG GKTL A+A+A+ +ATFIR
Sbjct: 186 CKEQIERLREVVELPLLSPERFVKLGIDPPKGIMLYGPPGTGKTLCARAVANRTDATFIR 245
Query: 205 VVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTL 264
V+GSELV+KY+GEGAR+V ELFE+A+ K IIF DEIDAIG R D+ GG+ EV RT+
Sbjct: 246 VIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAIGGARFDDGAGGDNEVQRTM 305
Query: 265 MQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHT 324
++L+ ++DGFDPRGN+KV+ ATNRP+ LD AL+RPGR DR +E LPD EGR IL++H
Sbjct: 306 LELITQLDGFDPRGNIKVLFATNRPNTLDEALMRPGRIDRKVEFGLPDLEGRAHILRIHA 365
Query: 325 RRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVL-G 382
+ M + K++ +IA + +GA+L+++ TEAGMFAIR RR T++DFL AV KV+ G
Sbjct: 366 KSMAIDKDIRWELIARLCPSQTGAELRSVCTEAGMFAIRARRRVATEKDFLDAVQKVVKG 425
Query: 383 NER 385
N++
Sbjct: 426 NQK 428
>gb|AAG20171.1| (AE005094) ATP-dependent 26S proteinase regulatory subunit 4
homolog; PrrIV1 [Halobacterium sp. NRC-1]
Length = 411
Score = 334 bits (847), Expect = 1e-90
Identities = 176/356 (49%), Positives = 251/356 (70%), Gaps = 4/356 (1%)
Query: 28 QLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY-NGPRF 86
+L+ Q+ +EA +E L E++RL+ E L+ + TV ++ +D A+++ + N
Sbjct: 41 ELQAQLDDVEARREELREEVNRLQRENETLKTASLYLATVEDLPEDGSAVIKQHGNNQEV 100
Query: 87 VVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLK 146
+ ++P + D L G RVA++ + ++ +L D EV E P+VTY DIGGL
Sbjct: 101 LTELSPRLA-DTLEVGDRVAIND-SFSVQRVLDDETDARAQAMEVDESPSVTYADIGGLD 158
Query: 147 KQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV 206
QL+E+REA+E PL +PE F+ VG++PP GVLL+GPPG GKT++AKA+A++ +A+FI++
Sbjct: 159 DQLREVREAVEDPLVNPEKFDAVGVEPPSGVLLHGPPGTGKTMLAKAVANQTDASFIKMA 218
Query: 207 GSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ 266
GSELVRK+IGEG+RLV +LFELA++K P IIFIDEIDA+ AKR D T G+ EV RT+MQ
Sbjct: 219 GSELVRKFIGEGSRLVRDLFELAEQKDPAIIFIDEIDAVAAKRTDSKTSGDAEVQRTMMQ 278
Query: 267 LLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRR 326
LL+EMDGFD RG++++IAATNR D+LD A+LRPGRFDRLIEVP P+ + R IL++H
Sbjct: 279 LLSEMDGFDERGDIRIIAATNRFDMLDSAILRPGRFDRLIEVPNPNPDARERILEIHAGE 338
Query: 327 MKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVL 381
M + +VD +A T SGA L ++ATEAGMFAIR+ R V ++DF A +K++
Sbjct: 339 MNVADSVDFSDLAADTAEFSGAQLASLATEAGMFAIRDDRDEVHRQDFDDAYEKLV 394
>gb|AAF22521.1|AF123390_1 (AF123390) 26S proteasome AAA-ATPase subunit RPT1a [Arabidopsis
thaliana]
Length = 426
Score = 333 bits (846), Expect = 2e-90
Identities = 162/352 (46%), Positives = 239/352 (67%), Gaps = 10/352 (2%)
Query: 36 LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIE 95
L +DK+ ++ E + +++ P +D + ++ +FVV + +
Sbjct: 73 LVSDKQMMQEEQPLQVARCTKIISPNT---------EDAKYVINVKQIAKFVVGLGDKVS 123
Query: 96 RDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREA 155
+ G RV +D+ I LP DP+V V E+P+VTYND+GG K+Q++++RE
Sbjct: 124 PTDIEEGMRVGVDRNKYQIQIPLPPKIDPSVTMMTVEEKPDVTYNDVGGCKEQIEKMREV 183
Query: 156 IELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYI 215
+ELP+ HPE F ++GIDPPKGVL YGPPG GKTL+A+A+A+ +A FIRV+GSELV+KY+
Sbjct: 184 VELPMLHPEKFVKLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYV 243
Query: 216 GEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
GEGAR+V ELF++A+ K I+F DE+DAIG R D+ GG+ EV RT+++++ ++DGFD
Sbjct: 244 GEGARMVRELFQMARSKKACIVFFDEVDAIGGARFDDGVGGDNEVQRTMLEIVNQLDGFD 303
Query: 276 PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDL 334
RGN+KV+ ATNRPD LDPALLR GR DR +E LPD E R +I K+HTR M +++
Sbjct: 304 ARGNIKVLMATNRPDTLDPALLRSGRLDRKVEFGLPDLESRTQIFKIHTRTMNCERDIRF 363
Query: 335 RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
++A + ++GAD++++ TEAGM+AIR RR VT++DFL AV+KV+ +K
Sbjct: 364 ELLARLCPNSTGADIRSVCTEAGMYAIRARRKTVTEKDFLDAVNKVIKGYQK 415
>pir||T41420 26S proteinase regulatory subunit 6b homolog - fission yeast
(Schizosaccharomyces pombe) >gi|3687465|emb|CAA21189.1|
(AL031798) 26s protease regulatory subunit 6b homolog
[Schizosaccharomyces pombe]
Length = 389
Score = 331 bits (839), Expect = 1e-89
Identities = 171/357 (47%), Positives = 237/357 (65%), Gaps = 2/357 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L+R++ L+LQ ++ D + L+REL R + E+ R++ P G +E +D + AIV +
Sbjct: 16 LERQLEMLDLQEGFIKEDCKSLKRELIRAQEEVKRIQSVPLVIGQFLEAIDQNTAIVGST 75
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G +VVRI ++R+ L+P A VAL + + A++++LP D ++ ERP+V+Y D
Sbjct: 76 TGSNYVVRILSTLDRELLKPSASVALQRHSNALVDILPPEADSSISMLRPDERPDVSYAD 135
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
+GGL Q QE+REA+ELPL +L+ ++GIDPP+GVLLYGPPG GKT++ KA+A+ A
Sbjct: 136 VGGLDVQKQEVREAVELPLTQGDLYRQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTAAN 195
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F +A+E AP IIFIDEIDAI KR D TG +REV
Sbjct: 196 FIRVVGSEFVQKYLGEGPRMVRDVFRMARENAPAIIFIDEIDAIATKRFDAQTGADREVQ 255
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVP-LPDFEGRLEIL 320
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE P D R +
Sbjct: 256 RILIELLTQMDGFDQGANVKVIMATNRADTLDPALLRPGRLDRKIEFPSYRDRRQRRLVF 315
Query: 321 KVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKA 376
+ T +M L VDL + +SGA + AI +AG+ A+R+ R + Q D +A
Sbjct: 316 QTITAKMLLSPEVDLDTFIMRPDASSGAQIAAIMQDAGLLAVRKSRGVILQSDIEEA 372
>gb|AAF02853.1|AC009324_2 (AC009324) Putative 26S proteasome ATPase subunit [Arabidopsis
thaliana]
Length = 451
Score = 331 bits (839), Expect = 1e-89
Identities = 167/352 (47%), Positives = 237/352 (66%), Gaps = 10/352 (2%)
Query: 36 LEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIE 95
L +DK+ ++ E L + +++ P +D + +V ++VV +
Sbjct: 97 LVSDKQMMQEEQPLLVATCTQIISPNT---------EDAKYVVDIKKIGKYVVGLGDKAS 147
Query: 96 RDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREA 155
+ G RV +DQ+ I LP DP+V V E+P+ TY+DIGG K+Q++++RE
Sbjct: 148 PTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREV 207
Query: 156 IELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYI 215
+ELP+ HPE F +GIDPPKGVL YGPPG GKTL+A+A+A+ A FIRVVGSELV+KYI
Sbjct: 208 VELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYI 267
Query: 216 GEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
GEGAR+V ELF++A+ K I+F DEIDAIG R D+ G + EV RT++++L ++DGFD
Sbjct: 268 GEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFD 327
Query: 276 PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDL 334
RGN+KV+ ATNRPDILDPALLRPGR DR +E LPD EGR +I K+HTR M +++
Sbjct: 328 ARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRF 387
Query: 335 RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
++A + ++GAD++++ EAGM+AI RR VT++DFL AV+KV+ +K
Sbjct: 388 ELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQK 439
>pir||T49507 probable 26S proteasome regulatory particle chain RPT1 [imported] -
Neurospora crassa >gi|7899363|emb|CAB91768.1| (AL356173)
probable 26S proteasome regulatory particle chain RPT1
[Neurospora crassa]
Length = 439
Score = 331 bits (839), Expect = 1e-89
Identities = 159/303 (52%), Positives = 218/303 (71%), Gaps = 1/303 (0%)
Query: 85 RFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGG 144
+FVV++ + + G RV +D+ I+ LP D +V V E+P+VTY D+GG
Sbjct: 126 KFVVQLGERVSPTDIEEGMRVGVDRNKYQILLPLPPKIDASVTMMTVEEKPDVTYGDVGG 185
Query: 145 LKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIR 204
K+Q+++LRE +E+PL PE F +GIDPPKG LLYGPPG GKTL A+A+A+ +ATFIR
Sbjct: 186 CKEQVEKLREVVEMPLLSPERFVNLGIDPPKGALLYGPPGTGKTLCARAVANRTDATFIR 245
Query: 205 VVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTL 264
V+GSELV+KY+GEGAR+V ELFE+A+ K IIF DEIDAIG R D+ GG+ EV RT+
Sbjct: 246 VIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAIGGARFDDGAGGDNEVQRTM 305
Query: 265 MQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHT 324
++L+ ++DGFD RGN+KV+ ATNRP LDPAL+RPGR DR IE LPD EGR IL++H
Sbjct: 306 LELITQLDGFDARGNIKVMFATNRPSTLDPALMRPGRIDRKIEFSLPDLEGRANILRIHA 365
Query: 325 RRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGN 383
+ M + +++ +I+ + A+GA+L+++ TEAGMFAIR RR +++DFL AVDKV+
Sbjct: 366 KSMSVERDIRWELISRLCPNATGAELRSVCTEAGMFAIRARRKVASEKDFLSAVDKVIKG 425
Query: 384 ERK 386
K
Sbjct: 426 NLK 428
>sp|P78578|PRS6_ASPNG 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG
>gi|1777414|gb|AAB40510.1| (U15601) 26S proteasome
subunit [Aspergillus niger]
Length = 423
Score = 324 bits (823), Expect = 8e-88
Identities = 169/358 (47%), Positives = 238/358 (66%), Gaps = 4/358 (1%)
Query: 12 HENYDDYITY--LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIE 69
++ D+Y T L+R + ++LQ ++ ++ L+REL R + E+ R++ P G +E
Sbjct: 36 NDGSDEYATLKRLQRHLEYIQLQEEYIKDEQRSLKRELVRAQEEIKRIQSVPLVIGQFME 95
Query: 70 VLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGF 129
+D + IVQ+ G +VVRI ++R+KL+P + VAL + + A++++LP D ++
Sbjct: 96 AIDQNTGIVQSSTGSNYVVRILSTLDREKLKPSSSVALHRHSNALVDILPPEADSSIAML 155
Query: 130 EVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTL 189
E+P+VTY D+GGL Q QE+REA+ELPL +L++++GIDPP+GVLLYGPPG GKT+
Sbjct: 156 GENEKPDVTYADVGGLDMQKQEIREAVELPLTQFDLYKQIGIDPPRGVLLYGPPGTGKTM 215
Query: 190 MAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR 249
+ KA+A+ A+FIRV GSE V+KY+GEG R+V ++F +A+E +P IIFIDEIDAI KR
Sbjct: 216 LVKAVANSTTASFIRVNGSEFVQKYLGEGPRMVRDVFRMARENSPAIIFIDEIDAIATKR 275
Query: 250 MDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVP 309
D TG +REV R L++LL +MDGF+ NVKVI ATNR D LDPALLRPGR DR IE P
Sbjct: 276 FDAQTGADREVQRILLELLNQMDGFEQSSNVKVIMATNRADTLDPALLRPGRLDRKIEFP 335
Query: 310 -LPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERR 365
L D R I +M L VDL + E SGA + AI EAG+ A+R+ R
Sbjct: 336 SLRDRRERRLIFSTIASKMSLSPEVDLDSLIVRNEPLSGAVIAAIMQEAGLRAVRKNR 393
>gi|11425970 proteasome (prosome, macropain) 26S subunit, ATPase, 4 [Homo
sapiens]
Length = 388
Score = 324 bits (821), Expect = 1e-87
Identities = 163/331 (49%), Positives = 225/331 (67%), Gaps = 1/331 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ + LE+Q ++ +++ L++E + E+ R++ P G +E +D + AIV +
Sbjct: 47 LQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGST 106
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G + VRI I+R+ L+P A VAL + + A++++LP D +++ ++P+V Y D
Sbjct: 107 TGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYAD 166
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
IGG+ Q QE+REA+ELPL H EL++++GIDPP+GVL+YGPPGCGKT++AKA+AH A
Sbjct: 167 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRVVGSE V+KY+GEG R+V ++F LAKE AP IIFIDEIDAI KR D TG +REV
Sbjct: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQ 286
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILK 321
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE PLPD + I
Sbjct: 287 RILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFS 346
Query: 322 VHTRRMKL-KNVDLRVIAEITEGASGADLKA 351
T +M L + VDL + SGAD+ +
Sbjct: 347 TITSKMNLSEEVDLEDYVARPDKISGADINS 377
>pir||S39349 MSS1 protein homolog - mouse
Length = 433
Score = 323 bits (820), Expect = 2e-87
Identities = 155/316 (49%), Positives = 222/316 (70%), Gaps = 1/316 (0%)
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEV 131
+D + I+ +F ++ + + G RV +D+ I LP DPTV +V
Sbjct: 107 EDPKYIINVKQFAKFEEDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQV 166
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
E+ + TY+D+GG K+Q+++L E +E PL HPE +GI+PPKGVLL+GPPG GKTL A
Sbjct: 167 EEKLDFTYSDVGGCKEQIEKLLEVVETPLLHPERLVNLGIEPPKGVLLFGPPGTGKTLCA 226
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A+A+ +A FIRV+GSELV+KY+GEGAR+V ELFE+A+ K +IF DE+DAIG R D
Sbjct: 227 RAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEMDAIGGARFD 286
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ GG+ EV RT+++L+ ++DGFDPRGN+KV+ ATNRPD LDPAL+RPGR DR IE LP
Sbjct: 287 DGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLP 346
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D EGR I K+H R M + +++ ++A + ++GA+++++ TEAGMFAIR RR T+
Sbjct: 347 DLEGRTHIFKIHARSMSVERDIGFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATE 406
Query: 371 EDFLKAVDKVLGNERK 386
+DFL+AV+KV+ + K
Sbjct: 407 KDFLEAVNKVIKSYAK 422
>gb|AAF91243.1|AF227499_1 (AF227499) proteasome regulatory ATPase subunit 1 [Trypanosoma
brucei]
Length = 437
Score = 322 bits (817), Expect = 4e-87
Identities = 161/318 (50%), Positives = 227/318 (70%), Gaps = 5/318 (1%)
Query: 72 DDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAI-IEL-LPSSKDPTVLGF 129
DD + +V + ++VV++ + R + RV + +I IE+ LP DP+V
Sbjct: 111 DDAKYVVAIRDTAKYVVKLGNRVARQDIEESMRVGVLVGYSSIHIEIPLPPRVDPSVSMM 170
Query: 130 EVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTL 189
+V E+P+VTYND+GG K+Q+ +RE +ELPL +PE + ++GIDPPKGVLLYGPPG GKTL
Sbjct: 171 QVEEKPDVTYNDVGGAKEQIDRIREVVELPLTNPEKYTQLGIDPPKGVLLYGPPGTGKTL 230
Query: 190 MAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR 249
+AKA+A+ +ATFIRV+GSELV++YIGEGAR++ E+F+LA+ K IIF DE+DA+G R
Sbjct: 231 LAKAVANRTDATFIRVIGSELVQRYIGEGARMIREIFQLARTKKAAIIFFDEVDAVGGAR 290
Query: 250 MDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVP 309
G+ E+ RT+++++ +MDGFD RGN+KVI ATNRPD LDPAL RPGR DR +EV
Sbjct: 291 --GGGDGDDEIQRTMLEMVNQMDGFDSRGNIKVIMATNRPDTLDPALTRPGRMDRKLEVG 348
Query: 310 LPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYV 368
LPD EGR +IL++H + + K + +IA + A+GADL+++ TEAGMFAIR RR +
Sbjct: 349 LPDLEGRTKILRIHAKSLSCEKAIRFELIARLCPNATGADLRSVCTEAGMFAIRARRKTI 408
Query: 369 TQEDFLKAVDKVLGNERK 386
++DFL AV+KV+ K
Sbjct: 409 NEKDFLDAVNKVIKGHHK 426
>gb|AAB70882.1| (U77918) spermatogenic cell/sperm-associated Tat-binding protein
homolog Sata [Rattus norvegicus]
Length = 442
Score = 321 bits (813), Expect = 1e-86
Identities = 168/394 (42%), Positives = 248/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL ++ ++ + P VIE+LD D
Sbjct: 46 QRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNNTLPYLVSNVIELLDVDPN 105
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 106 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 165
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 166 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 225
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 226 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 285
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL +MDGF P VKVIAATNR DILDPAL
Sbjct: 286 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQMDGFQPNTQVKVIAATNRVDILDPAL 345
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 346 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVE 405
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AGM A+R T +T ED+++ + +V ++ LQ
Sbjct: 406 AGMIALRRGATELTHEDYMEGILEVQAKKKANLQ 439
>gb|AAB88187.1| (AF035309) similar to 26S proteasome subunit p45 [Homo sapiens]
Length = 280
Score = 321 bits (813), Expect = 1e-86
Identities = 159/260 (61%), Positives = 207/260 (79%), Gaps = 1/260 (0%)
Query: 123 DPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGP 182
DP V V + P+ TY IGGL KQ++E++E IELP+KHPELFE +GI PKGVLLYGP
Sbjct: 6 DPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGP 65
Query: 183 PGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEI 242
PG GKTL+A+A+AH + TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEI
Sbjct: 66 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI 125
Query: 243 DAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRF 302
D+IG+ R++ +GG+ EV RT+++LL ++DGF+ N+KVI ATNR DILD ALLRPGR
Sbjct: 126 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI 185
Query: 303 DRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAI 361
DR IE P P+ E RL+ILK+H+R+M L + ++LR IAE+ GASGA++K + TEAGM+A+
Sbjct: 186 DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL 245
Query: 362 RERRTYVTQEDFLKAVDKVL 381
RERR +VTQEDF AV KV+
Sbjct: 246 RERRVHVTQEDFEMAVAKVM 265
>sp|Q63569|PRSA_RAT 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 1) (TBP-1)
(SPERMATOGENIC CELL/SPERM-ASSOCIATED TAT-BINDING PROTEIN
HOMOLOG SATA) >gi|1395184|dbj|BAA11939.1| (D83522)
proteasomal ATPase (rat TBP1) [Rattus norvegicus]
Length = 439
Score = 319 bits (810), Expect = 3e-86
Identities = 167/394 (42%), Positives = 248/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL ++ ++ + P VIE+LD D
Sbjct: 43 QRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 102
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 103 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 162
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 163 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 222
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 223 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 282
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 283 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPAL 342
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 343 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVE 402
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AGM A+R T +T ED+++ + +V ++ LQ
Sbjct: 403 AGMIALRRGATELTHEDYMEGILEVQAKKKANLQ 436
>gi|11437005 proteasome (prosome, macropain) 26S subunit, ATPase, 3 [Homo
sapiens]
Length = 423
Score = 319 bits (810), Expect = 3e-86
Identities = 167/394 (42%), Positives = 248/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL ++ ++ + P VIE+LD D
Sbjct: 27 QRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 86
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 87 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 146
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 147 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 206
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 207 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 266
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 267 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPAL 326
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 327 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVE 386
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AGM A+R T +T ED+++ + +V ++ LQ
Sbjct: 387 AGMIALRRGATELTHEDYMEGILEVQAKKKANLQ 420
>sp|O42586|PRSB_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 10)
(TBP-10) >gi|2648045|emb|CAA71486.1| (Y10460) TBP10
protein [Xenopus laevis]
Length = 404
Score = 318 bits (807), Expect = 6e-86
Identities = 167/394 (42%), Positives = 248/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL +R ++ + P VIE+LD D
Sbjct: 8 QRTRLLDSEIKIMKSEVLRVTHELQAMRDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 67
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 68 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 127
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 128 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 187
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 188 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFSLAKEKAPSI 247
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 248 IFIDELDAIGNKRFDSEKAGDREVQRTMLELLNQLDGFQPTTQVKVIAATNRVDILDPAL 307
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 308 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVE 367
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AG+ A+R T +T ED+++ + +V ++ LQ
Sbjct: 368 AGIIALRRGATELTHEDYMEGILEVQAKKKANLQ 401
>gb|AAB24840.1| Tat binding protein 1, TBP-1=transcriptional activator [human,
Peptide, 439 aa]
Length = 439
Score = 317 bits (805), Expect = 1e-85
Identities = 166/394 (42%), Positives = 247/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL ++ ++ + P VIE+LD D
Sbjct: 43 QRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 102
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 103 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 162
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 163 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 222
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 223 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 282
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 283 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPAL 342
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 343 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDPNGAQCKAVCVE 402
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AGM A+ T +T ED+++ + +V ++ LQ
Sbjct: 403 AGMIALARGATELTHEDYMEGILEVQAKKKANLQ 436
>sp|P33298|PRS6_YEAST 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG (YNT1 PROTEIN)
(TAT-BINDING HOMOLOG 2) >gi|313880|emb|CAA51972.1|
(X73570) 26S proteasome subunit Rpt3 [Saccharomyces
cerevisiae] >gi|458389|gb|AAA81916.1| (U06229) Ynt1p
[Saccharomyces cerevisiae]
Length = 428
Score = 317 bits (805), Expect = 1e-85
Identities = 167/357 (46%), Positives = 230/357 (63%), Gaps = 2/357 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ L LQ ++ ++ L+REL R + E+ R++ P G +E +D + IV +
Sbjct: 54 LEKEYELLTLQEDYIKDEQRHLKRELKRAQEEVKRIQSVPLVIGQFLEPIDQNTGIVSST 113
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G +VVRI ++R+ L+P VAL + + A++++LP D ++ E+P+VTY D
Sbjct: 114 TGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYAD 173
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
+GGL Q QE+REA+ELPL +L+E++GIDPP+GVLLYGPPG GKT++ KA+A+ A
Sbjct: 174 VGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAA 233
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRV GSE V KY+GEG R+V ++F LA+E AP+IIFIDE+D+I KR D TG +REV
Sbjct: 234 FIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQ 293
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVP-LPDFEGRLEIL 320
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE P L D R I
Sbjct: 294 RILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPYLRDRRERRLIF 353
Query: 321 KVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKA 376
+M L DL + + SGA + AI EAG+ A+R+ R + Q D +A
Sbjct: 354 GTIASKMSLAPEADLDSLIIRNDSLSGAVIAAIMQEAGLRAVRKNRYVILQSDLEEA 410
>gi|6320602 ATPase (AAA family) component of the 26S proteasome complex; Rpt3p
[Saccharomyces cerevisiae] >gi|2133217|pir||S69678 26S
proteasome regulatory particle chain RPT3 - yeast
(Saccharomyces cerevisiae) >gi|927327|gb|AAB64836.1|
(U32274) Yta2p; CAI: 0.21 [Saccharomyces cerevisiae]
Length = 428
Score = 317 bits (805), Expect = 1e-85
Identities = 167/357 (46%), Positives = 230/357 (63%), Gaps = 2/357 (0%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNY 81
L++ L LQ ++ ++ L+REL R + E+ R++ P G +E +D + IV +
Sbjct: 54 LEKEYELLTLQEDYIKDEQRHLKRELKRAQEEVKRIQSVPLVIGQFLEPIDQNTGIVSST 113
Query: 82 NGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND 141
G +VVRI ++R+ L+P VAL + + A++++LP D ++ E+P+VTY D
Sbjct: 114 TGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYAD 173
Query: 142 IGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNAT 201
+GGL Q QE+REA+ELPL +L+E++GIDPP+GVLLYGPPG GKT++ KA+A+ A
Sbjct: 174 VGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAA 233
Query: 202 FIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVN 261
FIRV GSE V KY+GEG R+V ++F LA+E AP+IIFIDE+D+I KR D TG +REV
Sbjct: 234 FIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQ 293
Query: 262 RTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVP-LPDFEGRLEIL 320
R L++LL +MDGFD NVKVI ATNR D LDPALLRPGR DR IE P L D R I
Sbjct: 294 RILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIF 353
Query: 321 KVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKA 376
+M L DL + + SGA + AI EAG+ A+R+ R + Q D +A
Sbjct: 354 GTIASKMSLAPEADLDSLIIRNDSLSGAVIAAIMQEAGLRAVRKNRYVILQSDLEEA 410
>gi|6679503 proteasome (prosome, macropain) 26S subunit, ATPase 3; Tat binding
protein 1 [Mus musculus] >gi|3510277|dbj|BAA32559.1|
(D49686) Tat binding protein-1 [Mus musculus]
>gi|10697242|dbj|BAB16347.1| (AB040858) proteasomal
ATPase [Mus musculus]
Length = 442
Score = 317 bits (805), Expect = 1e-85
Identities = 167/394 (42%), Positives = 247/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL ++ ++ + P VIE+LD D
Sbjct: 46 QRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 105
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 106 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 165
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 166 TLPTDYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 225
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 226 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 285
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 286 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPAL 345
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 346 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQSKAVCVE 405
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AGM A+R T +T ED ++ + +V ++ LQ
Sbjct: 406 AGMIALRRGATELTHEDHMEGILEVQAKKKANLQ 439
>gi|4506211 proteasome (prosome, macropain) 26S subunit, ATPase, 3 [Homo
sapiens] >gi|107855|pir||A34832 Tat-binding protein-1 -
human >gi|338700|gb|AAA36666.1| (M34079) tat binding
protein-1 (tbp-1) [Homo sapiens]
Length = 404
Score = 317 bits (804), Expect = 1e-85
Identities = 166/394 (42%), Positives = 247/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL ++ ++ + P VIE+LD D
Sbjct: 8 QRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 67
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 68 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 127
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 128 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 187
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 188 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 247
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 248 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPAL 307
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 308 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVE 367
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AGM A+ T +T ED+++ + +V ++ LQ
Sbjct: 368 AGMIALARGATELTHEDYMEGILEVQAKKKANLQ 401
>sp|P17980|PRSA_HUMAN 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 1) (TBP-1)
(PROTEASOME SUBUNIT P50)
Length = 439
Score = 317 bits (804), Expect = 1e-85
Identities = 166/394 (42%), Positives = 247/394 (62%), Gaps = 28/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL ++ ++ + P VIE+LD D
Sbjct: 43 QRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 102
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 103 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 162
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 163 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 222
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 223 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 282
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 283 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPAL 342
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A T+ +GA KA+ E
Sbjct: 343 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVE 402
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AGM A+ T +T ED+++ + +V ++ LQ
Sbjct: 403 AGMIALARGATELTHEDYMEGILEVQAKKKANLQ 436
>sp|O23894|PRSA_BRACM 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN
HOMOLOG 1) (TBP-1) >gi|2564337|dbj|BAA22951.1| (D88663)
Tat binding protein 1 [Brassica rapa]
Length = 424
Score = 316 bits (802), Expect = 2e-85
Identities = 171/394 (43%), Positives = 242/394 (61%), Gaps = 29/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRL-------RQPPAFAGTVIEVLD---- 72
R R LE ++R+L+ D +R E + ++ +Q P G ++E+L+
Sbjct: 27 RATRLLENEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYLVGNIVEILEMNPE 86
Query: 73 DDR-----------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAII 115
DD +++ + + ++ D L+PG V +++ + I+
Sbjct: 87 DDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLIL 146
Query: 116 ELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPK 175
+ LPS D V EV E+P YNDIGGL+KQ+QEL EAI LP+ H E FE++G+ PPK
Sbjct: 147 DTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPK 206
Query: 176 GVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPT 235
GVLLYGPPG GKTLMA+A A + NATF+++ G +LV+ +IG+GA+LV + F+LAKEKAP
Sbjct: 207 GVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPC 266
Query: 236 IIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPA 295
IIFIDEIDAIG KR D G+REV RT+++LL ++DGF +KVIAATNR DILDPA
Sbjct: 267 IIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPA 326
Query: 296 LLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIAT 354
L+R GR DR IE P P E R IL++H+R+M + +V+ +A T+ +GA LKA+
Sbjct: 327 LMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCV 386
Query: 355 EAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLL 388
EAGM A+R T V EDF + + +V ++ L
Sbjct: 387 EAGMLALRRDATEVNHEDFNEGIIQVQAKKKASL 420
>gb|AAF22525.1|AF123394_1 (AF123394) 26S proteasome AAA-ATPase subunit RPT5a [Arabidopsis
thaliana] >gi|7596759|gb|AAF64530.1| (AC009606) 26S
proteasome AAA-ATPase subunit RPT5a [Arabidopsis
thaliana]
Length = 424
Score = 316 bits (800), Expect = 4e-85
Identities = 170/396 (42%), Positives = 243/396 (60%), Gaps = 29/396 (7%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRL-------RQPPAFAGTVIEVLD-- 72
+ R R L+ ++R+L+ D +R E + ++ +Q P G ++E+L+
Sbjct: 25 ITRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYLVGNIVEILEMN 84
Query: 73 --DDR-----------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMA 113
DD +++ + + ++ D L+PG V +++ +
Sbjct: 85 PEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYL 144
Query: 114 IIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDP 173
I++ LPS D V EV E+P YNDIGGL+KQ+QEL EAI LP+ H E FE++G+ P
Sbjct: 145 ILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRP 204
Query: 174 PKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKA 233
PKGVLLYGPPG GKTLMA+A A + NATF+++ G +LV+ +IG+GA+LV + F+LAKEKA
Sbjct: 205 PKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKA 264
Query: 234 PTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILD 293
P IIFIDEIDAIG KR D G+REV RT+++LL ++DGF +KVIAATNR DILD
Sbjct: 265 PCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILD 324
Query: 294 PALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAI 352
PAL+R GR DR IE P P E R IL++H+R+M + +V+ +A T+ +GA LKA+
Sbjct: 325 PALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAV 384
Query: 353 ATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLL 388
EAGM A+R T V EDF + + +V ++ L
Sbjct: 385 CVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASL 420
>gb|AAD46145.1| (AF081573) 19S proteasome regulatory complex subunit S6A
[Arabidopsis thaliana]
Length = 424
Score = 314 bits (796), Expect = 1e-84
Identities = 170/396 (42%), Positives = 241/396 (59%), Gaps = 29/396 (7%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRL-------RQPPAFAGTVIEVLD-- 72
+ R R L+ ++R+L+ D +R E + ++ +Q P G ++E+L+
Sbjct: 25 ITRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYLVGNIVEILEMN 84
Query: 73 --DDR-----------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMA 113
DD +++ + + ++ D L+PG V +++ +
Sbjct: 85 PEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYL 144
Query: 114 IIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDP 173
I++ LPS D V EV E+P YNDIGGL+KQ+QEL EAI LP+ H E FE++G+ P
Sbjct: 145 ILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRP 204
Query: 174 PKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKA 233
PKGVLLYGPPG GKTLMA+A A + NATF+++ G +LV+ +IG+GA+LV + F+LAKEKA
Sbjct: 205 PKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKA 264
Query: 234 PTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILD 293
P IIFIDEIDAIG KR D G+REV RT+++LL ++DGF +KVIAATNR DILD
Sbjct: 265 PCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILD 324
Query: 294 PALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAI 352
PAL+R GR DR IE P P E R IL++H+R+M + +V +A T+ GA LKA+
Sbjct: 325 PALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVHFEELARSTDDFHGAQLKAV 384
Query: 353 ATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLL 388
EAGM A+R T V EDF + + +V ++ L
Sbjct: 385 CVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASL 420
>sp|P46465|PRSA_ORYSA 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN
HOMOLOG 1) (TBP-1) >gi|556560|dbj|BAA04614.1| (D17788)
rice homologue of Tat binding protein [Oryza sativa]
Length = 429
Score = 314 bits (795), Expect = 1e-84
Identities = 169/395 (42%), Positives = 248/395 (62%), Gaps = 29/395 (7%)
Query: 16 DDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD--- 72
D+ LK +++ L+V E+ KE+++ +++ +Q P G ++E+L+
Sbjct: 38 DNETRVLKDELQRTNLEV---ESYKEKIKENQEKIKLN----KQLPYLVGNIVEILEMNP 90
Query: 73 DDRA------------------IVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAI 114
+D A +++ + + ++ +KL+PG V +++ + I
Sbjct: 91 EDEAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVIGLVDPEKLKPGDLVGVNKDSYLI 150
Query: 115 IELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPP 174
++ LPS D V EV E+P YNDIGGL+KQ+QEL EAI LP+ H + F+++GI PP
Sbjct: 151 LDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKDRFQKLGIRPP 210
Query: 175 KGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAP 234
KGVLLYGPPG GKTLMA+A A + NATF+++ G +LV+ +IG+GA+LV + F+LAKEK+P
Sbjct: 211 KGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKSP 270
Query: 235 TIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDP 294
IIFIDEIDAIG KR D G+REV RT+++LL ++DGF +KVIAATNR DILDP
Sbjct: 271 CIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDP 330
Query: 295 ALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIA 353
AL+R GR DR IE P P E R IL++H+R+M + +V+ +A T+ +GA LKA+
Sbjct: 331 ALMRSGRLDRKIEFPHPSEEARARILQIHSRKMNVNPDVNFEELARSTDDFNGAQLKAVC 390
Query: 354 TEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLL 388
EAGM A+R T VT EDF + + +V ++ L
Sbjct: 391 VEAGMLALRRDATEVTHEDFNEGIIQVQAKKKSSL 425
>sp|P54776|PRSA_LYCES 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN
HOMOLOG 1) (TBP-1) (MG(2+)-DEPENDENT ATPASE 1) (LEMA-1)
>gi|1362099|pir||S56672 probable 26S proteinase chain
MA-1 - tomato >gi|732815|emb|CAA52445.1| (X74426)
Mg-dependent ATPase 1 [Lycopersicon esculentum]
Length = 423
Score = 312 bits (792), Expect = 3e-84
Identities = 167/394 (42%), Positives = 245/394 (61%), Gaps = 29/394 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRL-------RQPPAFAGTVIEVLD---- 72
R R L+ ++R+++ + +R EL + ++ +Q P G ++E+L+
Sbjct: 26 RASRLLDNEIRIIKEELQRTNLELDSFKEKIKENQEKIKLNKQLPYLVGNIVEILEMNPE 85
Query: 73 ----DDRA-------------IVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAII 115
+D A +++ + + ++ D L+PG V +++ + I+
Sbjct: 86 EEAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDNLKPGDLVGVNKDSYLIL 145
Query: 116 ELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPK 175
+ LPS D V EV E+P Y+DIGGL+KQ+QEL EAI LP+ H E F+++G+ PPK
Sbjct: 146 DTLPSEYDSRVKAMEVDEKPTEDYHDIGGLEKQIQELVEAIVLPMTHQERFQKLGVRPPK 205
Query: 176 GVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPT 235
GVLLYGPPG GKTLMA+A A + NATF+++ G +LV+ +IG+GA+LV + F+LAKEK+P
Sbjct: 206 GVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKSPC 265
Query: 236 IIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPA 295
IIFIDEIDAIG KR D G+REV RT+++LL ++DGF +KVIAATNR DILDPA
Sbjct: 266 IIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDDRIKVIAATNRADILDPA 325
Query: 296 LLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIAT 354
L+R GR DR IE P P E R IL++H+R+M + +V+ +A T+ +GA LKA+
Sbjct: 326 LMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVNPDVNFEELARSTDDFNGAQLKAVCV 385
Query: 355 EAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLL 388
EAGM A+R T VT EDF + + +V ++ L
Sbjct: 386 EAGMLALRRDATEVTHEDFNEGIIQVQAKKKASL 419
>sp|O04019|PRSA_ARATH 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN
HOMOLOG 1) (TBP-1) >gi|2342675|gb|AAB70397.1| (AC000106)
Similar to probable Mg-dependent ATPase (pir|S56671).
ESTs gb|T46782,gb|AA04798 come from this gene.
[Arabidopsis thaliana]
Length = 419
Score = 311 bits (789), Expect = 8e-84
Identities = 168/389 (43%), Positives = 240/389 (61%), Gaps = 22/389 (5%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD----DDR-- 75
L IR L+ + + D E ++ ++ + ++ +Q P G ++E+L+ DD
Sbjct: 27 LANEIRILKEESQRTNLDLESVKEKIKENQEKIKLNKQLPYLVGNIVEILEMSPEDDAEE 86
Query: 76 ---------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPS 120
+++ + + ++ D L+PG V +++ + I++ LPS
Sbjct: 87 DGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDTLKPGDLVGVNKDSYLILDTLPS 146
Query: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
D V EV E+P YNDIGGL+KQ+QEL EAI LP+ H E FE++GI PPKGVLLY
Sbjct: 147 EYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKEQFEKLGIRPPKGVLLY 206
Query: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
GPPG GKTLMA+A A + NATF+++ G +LV+ +IG+GA+LV + F LAKEK+P IIFID
Sbjct: 207 GPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFLLAKEKSPCIIFID 266
Query: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
EIDAIG KR D G+REV RT+++LL ++DGF +KVIAATNR DILDPAL+R G
Sbjct: 267 EIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDDRIKVIAATNRADILDPALMRSG 326
Query: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMF 359
R DR IE P P E R IL++H+R+M + +V+ +A T+ +GA LKA+ EAGM
Sbjct: 327 RLDRKIEFPHPTEEARGRILQIHSRKMNVNADVNFEELARSTDDFNGAQLKAVCVEAGML 386
Query: 360 AIRERRTYVTQEDFLKAVDKVLGNERKLL 388
A+R T V EDF + + +V ++ L
Sbjct: 387 ALRRDATEVNHEDFNEGIIQVQAKKKASL 415
>pir||T33155 hypothetical protein F56H1.4 - Caenorhabditis elegans
>gi|3193161|gb|AAC19196.1| (AF067618) contains
similarity to the AAA family of ATPases (Pfam; AAA,
score; 259.07); most similar to human probable 26S
protease subunit TBP-1 (SW:P17980) [Caenorhabditis
elegans]
Length = 430
Score = 309 bits (784), Expect = 3e-83
Identities = 160/393 (40%), Positives = 245/393 (61%), Gaps = 26/393 (6%)
Query: 22 LKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLD-D 73
LK R L+ ++R++ ++ +R+ + L+ + + P V+E+LD +
Sbjct: 34 LKSRTHLLDNEIRIMRSEVQRINHSATTLKERIKENTERIKVNKTLPYLVSNVVELLDLE 93
Query: 74 DR-----------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
D A+++ + + + ++ D+L+PG V +++ + I+E
Sbjct: 94 DNTEEEGANVDLDAQKTKCAVIKTSTRATYFLPVVGLVDPDELKPGDLVGVNKDSYLILE 153
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGG KQ+QEL EA+ LP+ H + F +GI PPKG
Sbjct: 154 KLPAEYDSRVKAMEVDERPTEQYSDIGGCDKQIQELIEAVVLPMTHKDRFVNLGIHPPKG 213
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKT+MA+A+A + +TF+++ G +LV+ +IG+GA+LV + F LAKEKAP I
Sbjct: 214 VLMYGPPGTGKTMMARAVAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAI 273
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P ++KVIAATNR D+LDPAL
Sbjct: 274 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNDDIKVIAATNRIDVLDPAL 333
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE+P P+ + R I+++H+R+M + K+V+ +A T+ +GA KA+ E
Sbjct: 334 LRSGRLDRKIELPHPNEDARARIMQIHSRKMNVNKDVNFEELARCTDDFNGAQCKAVCVE 393
Query: 356 AGMFAIRERRTYVTQEDFLKAVDKVLGNERKLL 388
AGM A+R T + EDF+ A+ +V ++ L
Sbjct: 394 AGMIALRRDATEILHEDFMDAILEVQAKKKASL 426
>gi|6324691 26S protease regulatory subunit; Rpt5p [Saccharomyces cerevisiae]
>gi|464859|sp|P33297|PRSA_YEAST 26S PROTEASE REGULATORY
SUBUNIT 6A (TAT-BINDING PROTEIN HOMOLOG 1) (TBP-1)
>gi|626983|pir||S46605 26S proteasome regulatory
particle chain RPT5 - yeast (Saccharomyces cerevisiae)
>gi|313878|emb|CAA51971.1| (X73569) yeast tat-binding
analog [Saccharomyces cerevisiae]
>gi|1050819|emb|CAA62114.1| (X90518) ORF O3258
[Saccharomyces cerevisiae] >gi|1164962|emb|CAA64037.1|
(X94335) YOR3258w [Saccharomyces cerevisiae]
>gi|1420311|emb|CAA99315.1| (Z75025) ORF YOR117w
[Saccharomyces cerevisiae]
Length = 434
Score = 308 bits (780), Expect = 9e-83
Identities = 165/399 (41%), Positives = 249/399 (62%), Gaps = 34/399 (8%)
Query: 22 LKRRIRQLELQVRMLEADKERLERE----LSRLRSEMSRL---RQPPAFAGTVIEVLD-- 72
L+ R + L+ ++R+ ++ +RL E L +++ ++ RQ P V+EV+D
Sbjct: 30 LQTRAKLLDNEIRIFRSELQRLSHENNVMLEKIKDNKEKIKNNRQLPYLVANVVEVMDMN 89
Query: 73 --DDR----------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALD 108
+D+ A+V+ + + + ++ DKL+P V ++
Sbjct: 90 EIEDKENSESTTQGGNVNLDNTAVGKAAVVKTSSRQTVFLPMVGLVDPDKLKPNDLVGVN 149
Query: 109 QRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEE 168
+ + I++ LPS D V EV E+P TY+D+GGL KQ++EL EAI LP+K + F++
Sbjct: 150 KDSYLILDTLPSEFDSRVKAMEVDEKPTETYSDVGGLDKQIEELVEAIVLPMKRADKFKD 209
Query: 169 VGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFEL 228
+GI PKG L+YGPPG GKTL+A+A A + NATF+++ +LV+ YIGEGA+LV + F L
Sbjct: 210 MGIRAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAAPQLVQMYIGEGAKLVRDAFAL 269
Query: 229 AKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNR 288
AKEKAPTIIFIDE+DAIG KR D G+REV RT+++LL ++DGF VKV+AATNR
Sbjct: 270 AKEKAPTIIFIDELDAIGTKRFDSEKSGDREVQRTMLELLNQLDGFSSDDRVKVLAATNR 329
Query: 289 PDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGA 347
D+LDPALLR GR DR IE PLP + R +IL++H+R+M +++ + +A T+ +GA
Sbjct: 330 VDVLDPALLRSGRLDRKIEFPLPSEDSRAQILQIHSRKMTTDDDINWQELARSTDEFNGA 389
Query: 348 DLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERK 386
LKA+ EAGM A+R ++ V EDF++ + +V + K
Sbjct: 390 QLKAVTVEAGMIALRNGQSSVKHEDFVEGISEVQARKSK 428
>gb|AAB42248.1| (U88170) Contains similarity to Pfam domain: PF00004 (AAA),
Score=322.1, E-value=2.1e-93, N=1 [Caenorhabditis
elegans]
Length = 493
Score = 308 bits (780), Expect = 9e-83
Identities = 175/375 (46%), Positives = 241/375 (63%), Gaps = 17/375 (4%)
Query: 17 DYITYLKRRI-RQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDR 75
DY+ K I RQ R L K R E++L + LR P V E+ DD++
Sbjct: 113 DYLQLEKEFITRQTSRHGRPLAVQKRR-EQQL------VQSLRGTPTTLARVHELFDDEK 165
Query: 76 AIVQNYNGPR--FVVRIAPWIERDKLRPGARVALDQRTM------AIIELLPSSKDPTVL 127
V G R + V I +++D LR A V + M AI+ +L D +
Sbjct: 166 HAVVVVEGSRREWYVPILSIVDKDLLRLNALVMVKAGGMFKTVPSAIVGVLDDKIDSNAM 225
Query: 128 GFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGK 187
G +V + P T++DIGG + Q+QEL+E++ELPL HPE +EE+GI PKGV+LYG PG GK
Sbjct: 226 GHKVEKTPKETFDDIGGCESQIQELKESVELPLTHPEYYEEMGITAPKGVILYGEPGTGK 285
Query: 188 TLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGA 247
TL+AKA+A+ +ATFIR GS+LV+K GEGARLV ++F++AKE+AP+I+FIDEIDA+G
Sbjct: 286 TLLAKAVANSTSATFIRATGSDLVQKQSGEGARLVRQIFQMAKEQAPSIVFIDEIDAVGT 345
Query: 248 KRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIE 307
KR D ++ GE+EV RTL++LL ++DGF+ RG+VK+I ATNR D LDPAL+RPGR DR IE
Sbjct: 346 KRFDTSSRGEQEVQRTLLELLNQLDGFESRGDVKIIMATNRIDSLDPALIRPGRIDRKIE 405
Query: 308 VPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRT 366
+P PD + R +I +HT M + K V + + SGA++KA+ TEAGM A+R +R
Sbjct: 406 LPKPDEKTRQKIFTIHTSGMTIQKAVTYENVLGKEKSISGAEIKAVCTEAGMLALRAQRK 465
Query: 367 YVTQEDFLKAVDKVL 381
V +DF KAV V+
Sbjct: 466 CVGTDDFEKAVKSVM 480
>pir||T44596 26S proteasome regulatory complex chain p50 [imported] - fruit fly
(Drosophila melanogaster)
>gi|5679018|gb|AAD46823.1|AF160882_1 (AF160882)
BcDNA.GH12068 [Drosophila melanogaster]
>gi|6434948|gb|AAF08386.1|AF145305_1 (AF145305) 26S
proteasome regulatory complex subunit p50 [Drosophila
melanogaster] >gi|7301041|gb|AAF56177.1| (AE003744) Rpt5
gene product [Drosophila melanogaster]
Length = 428
Score = 308 bits (780), Expect = 9e-83
Identities = 154/323 (47%), Positives = 219/323 (67%), Gaps = 5/323 (1%)
Query: 68 IEVLDDDR----AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKD 123
+ VLD+ R A+++ + + + ++ +KL+PG V +++ + I+E LP+ D
Sbjct: 99 VTVLDNQRKGKCAVIKTSTRQAYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPAEYD 158
Query: 124 PTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPP 183
V EV ERP Y+DIGGL KQ+QEL EA+ LP+ H E F+ +GI PPKGVLLYGPP
Sbjct: 159 ARVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKGVLLYGPP 218
Query: 184 GCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEID 243
G GKTL+A+A A + +TF+++ G +LV+ +IG+GA+LV + F LAKEKAP IIFIDE+D
Sbjct: 219 GTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELD 278
Query: 244 AIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFD 303
AIG KR D G+REV RT+++LL ++DGF ++KVIAATNR DILDPALLR GR D
Sbjct: 279 AIGTKRFDSEKAGDREVQRTMLELLNQLDGFSSTADIKVIAATNRVDILDPALLRSGRLD 338
Query: 304 RLIEVPLPDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIR 362
R IE P P+ E R I+++H+R+M + N V+ ++ T+ +GA KA+ EAGM A+R
Sbjct: 339 RKIEFPHPNEEARARIMQIHSRKMNVSNDVNFEELSRSTDDFNGAQCKAVCVEAGMIALR 398
Query: 363 ERRTYVTQEDFLKAVDKVLGNER 385
VT EDF+ A+ +V ++
Sbjct: 399 RSANSVTHEDFMDAIMEVQAKKK 421
>gb|AAF91247.1|AF227503_1 (AF227503) proteasome regulatory ATPase subunit 5 [Trypanosoma
brucei]
Length = 445
Score = 304 bits (770), Expect = 1e-81
Identities = 165/392 (42%), Positives = 239/392 (60%), Gaps = 23/392 (5%)
Query: 20 TYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD---DDR- 75
T L+R I QL+ + R + ++ L RE+ + + + P ++ EVLD DD+
Sbjct: 50 TQLQREIHQLKNEERTMSSELAGLRREVEESQKRVRDSNKLPYLVASIAEVLDLEADDQD 109
Query: 76 -----------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELL 118
AI++ + + + ++ +KL P V +++ T ++E L
Sbjct: 110 VEELNVGKKKSRHPQKSAIIKTSSRQTVFLPVVGLVDANKLSPQDLVGVNKDTFLVLEEL 169
Query: 119 PSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVL 178
P D V E++E+P Y D+GGL KQ+ E+ EA+ LP+ E + +GI PPKGVL
Sbjct: 170 PPEYDSRVKAMEIVEKPKEKYTDVGGLDKQINEMIEAVVLPITEKEKYVRIGIKPPKGVL 229
Query: 179 LYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIF 238
LYG PG GKT++A+A A +A F+R+ G +LV+ YIGEGAR++ + F LAK++APTIIF
Sbjct: 230 LYGSPGTGKTMLARACAASTDACFLRLAGPQLVQMYIGEGARILRDAFALAKKRAPTIIF 289
Query: 239 IDEIDAIGAKRMDE-TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALL 297
IDE+DAIG++R DE + G REV R +++LL+ +DGF +VKVIAATNR D+LDPALL
Sbjct: 290 IDELDAIGSRRSDEGSKHGSREVQRRMLELLSLLDGFGSTDDVKVIAATNRIDVLDPALL 349
Query: 298 RPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEA 356
R GR DR +E LPD E R IL++H+RRM L +V+ I+ +TE +GA LKA+ EA
Sbjct: 350 RRGRIDRKVEFTLPDEEARAHILQIHSRRMALHGDVNFEEISRMTEDMNGAQLKAVCVEA 409
Query: 357 GMFAIRERRTYVTQEDFLKAVDKVLGNERKLL 388
GM A+R R YV EDF + V V ++ L
Sbjct: 410 GMLALRNERVYVAHEDFAEGVTAVQARKKSSL 441
>sp|O14126|PRSA_SCHPO 26S PROTEASE REGULATORY SUBUNIT 6A >gi|7435746|pir||T11634 26S
proteasome regulatory particle chain RPT5 - fission
yeast (Schizosaccharomyces pombe)
>gi|2414640|emb|CAB16387.1| (Z99260) probable 26s
protease regulatory subunit 6a. [Schizosaccharomyces
pombe] >gi|6681372|dbj|BAA88693.1| (AB012136) regulatory
subunit of 26S proteasome [Schizosaccharomyces pombe]
Length = 438
Score = 298 bits (755), Expect = 7e-80
Identities = 160/400 (40%), Positives = 244/400 (61%), Gaps = 29/400 (7%)
Query: 19 ITYLKRRIRQLELQVRMLEADKERLERELSRL-------RSEMSRLRQPPAFAGTVIEVL 71
I L R R LE +++++++ +RL E S + + ++S + P G V+E+L
Sbjct: 36 IDELNSRTRLLENDIKVMKSEFQRLTHEKSTMLEKIKENQEKISNNKMLPYLVGNVVEIL 95
Query: 72 D---------------------DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQR 110
D A+++ + + +E ++L PG + +++
Sbjct: 96 DMQPDEVDVQESANQNSEATRVGKSAVIKTSTRQTIFLPLIGLVEPEELHPGDLIGVNKD 155
Query: 111 TMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVG 170
+ II+ LPS D V EV E+P Y+DIGGL KQ++EL EAI LP++ + F ++G
Sbjct: 156 SYLIIDKLPSEYDSRVKAMEVDEKPTERYSDIGGLSKQIEELFEAIVLPMQQADKFRKLG 215
Query: 171 IDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAK 230
+ PPKG L++GPPG GKTL+A+A A + NATF+++ +LV+ +IG+GA+LV + F LAK
Sbjct: 216 VKPPKGCLMFGPPGTGKTLLARACAAQSNATFLKLAAPQLVQMFIGDGAKLVRDAFALAK 275
Query: 231 EKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPD 290
EK+P IIFIDE+DAIG KR D G+REV RT+++LL ++DGF VKVIAATNR D
Sbjct: 276 EKSPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSSDDRVKVIAATNRVD 335
Query: 291 ILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADL 349
LDPALLR GR DR +E PLP+ E R+ IL++H+R+M + +++ +A T+ +GA L
Sbjct: 336 TLDPALLRSGRLDRKLEFPLPNEEARVGILRIHSRKMAIDDDINWEELARSTDEYNGAML 395
Query: 350 KAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
K++ EAGM A+R+ T + E F+ + +V + K LQ
Sbjct: 396 KSVCVEAGMIALRQGDTKINHEHFMDGILEVQMRKSKTLQ 435
>sp|O42587|PRSA_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 6) (TBP-6)
>gi|2648047|emb|CAA71487.1| (Y10461) TBP6 protein
[Xenopus laevis]
Length = 405
Score = 296 bits (751), Expect = 2e-79
Identities = 158/371 (42%), Positives = 228/371 (60%), Gaps = 28/371 (7%)
Query: 24 RRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQP-------PAFAGTVIEVLDDDR- 75
+R R L+ ++++++++ R+ EL +R ++ + P VIE+LD D
Sbjct: 27 QRTRLLDSEIKIMKSEVLRVTHELQAMRDKIKENSEKIKVNKTLPYLVSNVIELLDVDPN 86
Query: 76 -------------------AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIE 116
A+++ + + + ++ +KL+PG V +++ + I+E
Sbjct: 87 DQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILE 146
Query: 117 LLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKG 176
LP+ D V EV ERP Y+DIGGL KQ+QEL EAI LP+ H E FE +GI PPKG
Sbjct: 147 TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKG 206
Query: 177 VLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTI 236
VL+YGPPG GKTL+A+A A + ATF+++ G +LV+ +IG+GA+LV + F LAKEKAP+I
Sbjct: 207 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSI 266
Query: 237 IFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPAL 296
IFIDE+DAIG KR D G+REV RT+++LL ++DGF P VKVIAATNR DILDPAL
Sbjct: 267 IFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNMQVKVIAATNRVDILDPAL 326
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATE 355
LR GR DR IE P+P+ E R I+++H+R+M + +V+ +A + K E
Sbjct: 327 LRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCPTISMALSAKQFGVE 386
Query: 356 AGMFAIRERRT 366
AGM A+R T
Sbjct: 387 AGMIALRRGAT 397
>gb|AAD24194.1|AF134402_1 (AF134402) Tat-binding protein-1 [Drosophila melanogaster]
Length = 431
Score = 294 bits (744), Expect = 1e-78
Identities = 149/323 (46%), Positives = 216/323 (66%), Gaps = 6/323 (1%)
Query: 68 IEVLDDDR----AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKD 123
+ VLD+ R A+++ + + + ++ +KL+PG +++ I+E LP+ D
Sbjct: 103 VTVLDNQRKGKCAVIKTSTRQAYFLPVIGLVDAEKLKPGDLAGVNKDFYLILETLPAEYD 162
Query: 124 PTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPP 183
V EV ERP ++DIGGL KQ+QEL EA+ LP+ H E F+ +GI PPKGV+LYGPP
Sbjct: 163 ARVKAMEVDERPTEQFSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKGVILYGPP 222
Query: 184 GCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEID 243
G GKTL+A+A A + +TF+++ G +LV+ +IG+GA+LV + F LAKEKAP IIFIDE+D
Sbjct: 223 GTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELD 282
Query: 244 AIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFD 303
AIG KR D G+REV RT+++LL +++GF ++KVIAATNR DIL PALLR GR D
Sbjct: 283 AIGTKRFDSEKAGDREVQRTMLELLNQLNGFSSTADIKVIAATNRVDIL-PALLRSGRLD 341
Query: 304 RLIEVPLPDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIR 362
R IE P P+ E R I+++H+R+M + N V+ ++ T+ +GA KA+ EAGM A+R
Sbjct: 342 RKIEFPHPNEEARARIMQIHSRKMNVSNDVNFEELSRSTDDFNGAQCKAVCVEAGMIALR 401
Query: 363 ERRTYVTQEDFLKAVDKVLGNER 385
VT EDF+ A+ +V ++
Sbjct: 402 RSANSVTHEDFMDAIMEVQAKKK 424
>pir||H71114 probable cell division control protein (transitional endoplasmic
reticulum ATPase) - Pyrococcus horikoshii
>gi|3257095|dbj|BAA29778.1| (AP000003) 840aa long
hypothetical cell division control protein (transitional
endoplasmic reticulum ATPase) [Pyrococcus horikoshii]
Length = 840
Score = 267 bits (676), Expect = 1e-70
Identities = 148/287 (51%), Positives = 191/287 (65%), Gaps = 21/287 (7%)
Query: 123 DPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGP 182
+P+ L +IE PNV ++DIGGL++ QELREA+E PLK+P+ F+++GI PPKGVLLYGP
Sbjct: 530 EPSALREVLIEVPNVHWDDIGGLEEVKQELREAVEWPLKYPKAFKKLGITPPKGVLLYGP 589
Query: 183 PGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEI 242
PG GKTL+AKA+A E A FI V G E++ K++GE + + E+F A++ AP IIFIDEI
Sbjct: 590 PGTGKTLLAKAVATESEANFIAVRGPEVLSKWVGESEKRIREIFRKARQAAPAIIFIDEI 649
Query: 243 DAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRF 302
DAI R T+ GE+ +R + QLL EMDG V VIAATNRPDILDPALLRPGRF
Sbjct: 650 DAIAPAR--GTSEGEKVTDRIINQLLTEMDGLVENSGVVVIAATNRPDILDPALLRPGRF 707
Query: 303 DRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAI 361
DRLI VP PD E R EI KVHTR M L +VDLR +A TEG +GAD+ A+ EA + A+
Sbjct: 708 DRLILVPAPDEEARFEIFKVHTRSMPLADDVDLRELARRTEGYTGADIAAVCREAALNAL 767
Query: 362 RE------------------RRTYVTQEDFLKAVDKVLGNERKLLQQ 390
R + VT++DF +A+ KV + K + +
Sbjct: 768 RRVVKSVPKEKLEEESEEFLNKLVVTRKDFEEALKKVKPSVSKYMME 814
Score = 239 bits (604), Expect = 4e-62
Identities = 123/196 (62%), Positives = 147/196 (74%), Gaps = 3/196 (1%)
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P VTY DIGGLK+ +Q++RE +ELPLKHPELFE +GI+PPKGVLLYGPPG GKTL+AKA+
Sbjct: 207 PEVTYEDIGGLKEAIQKIREMVELPLKHPELFERLGIEPPKGVLLYGPPGTGKTLLAKAV 266
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
A+E NA FI + G E++ KY GE + E+F+ A+E AP IIFIDEIDAI KR E
Sbjct: 267 ANEANAYFIAINGPEIMSKYYGESEERLREIFKEAEENAPAIIFIDEIDAIAPKR--EEV 324
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
GE E R + QLL MDG RG V VI ATNRPD LDPAL RPGRFDR IEV +PD +
Sbjct: 325 VGEVE-KRVVSQLLTLMDGLKGRGKVIVIGATNRPDALDPALRRPGRFDREIEVGVPDKQ 383
Query: 315 GRLEILKVHTRRMKLK 330
GR EIL++HTR M ++
Sbjct: 384 GRKEILQIHTRGMPIE 399
>gi|11499681 cell division control protein 48, AAA family (cdc48-2)
[Archaeoglobus fulgidus] >gi|7435750|pir||B69512 cell
division control protein 48, AAA family (cdc48-2)
homolog - Archaeoglobus fulgidus
>gi|2648442|gb|AAB89157.1| (AE000959) cell division
control protein 48, AAA family (cdc48-2) [Archaeoglobus
fulgidus]
Length = 811
Score = 259 bits (654), Expect = 5e-68
Identities = 167/391 (42%), Positives = 229/391 (57%), Gaps = 36/391 (9%)
Query: 7 DEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERE-LSRLRSEMSRLR------Q 59
D+ + +N D +L I+ E + + A K L +E + L E+++ Q
Sbjct: 404 DDPELIKNLD----FLYDEIKNSETEEEVKGAVKNLLPQEVIDELEVEITKAMLRSLADQ 459
Query: 60 PPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDK------LRPGARVALDQRTMA 113
F G IE L + A+ + + R P I+ ++ L RV D A
Sbjct: 460 THGFVGADIEALCKEAAM-------KALRRYLPQIDLNEDEIPIELLESIRVTWDDFMDA 512
Query: 114 IIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDP 173
+ E+ PS+ +E P VT+ND+GGL+ +E+ EA+E PLK+PE F++ GI P
Sbjct: 513 LREIEPSAMREVF-----VEIPKVTWNDVGGLEDVKREIIEAVEWPLKYPEKFKKFGIKP 567
Query: 174 PKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKA 233
PKGVLLYGPPG GKTL+AKA+A+E A FI + G +++ K++GE + V ++F A++ A
Sbjct: 568 PKGVLLYGPPGTGKTLIAKAVANESEANFISIKGGQILSKWLGESEKAVRKIFRKARQVA 627
Query: 234 PTIIFIDEIDAIGAKR-MDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDIL 292
P IIF DEIDAI R +DE G R V R L QLL EMDG + V VI ATNRPDIL
Sbjct: 628 PCIIFFDEIDAIAQMRGIDE---GSRAVERVLNQLLTEMDGLEELHGVVVIGATNRPDIL 684
Query: 293 DPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKA 351
DPALLRPGRFDR++ V PD + RL I K+HTR M L ++VDL +A++TEG GAD++A
Sbjct: 685 DPALLRPGRFDRMVYVRPPDKKSRLAIFKIHTRDMPLSEDVDLEELADLTEGYVGADIEA 744
Query: 352 IATEAGMFAIRE--RRTYVTQEDFLKAVDKV 380
I EA M AIRE V FL+A+ K+
Sbjct: 745 ICREAVMLAIRENINAEKVEMRHFLEALKKI 775
Score = 242 bits (610), Expect = 7e-63
Identities = 124/233 (53%), Positives = 162/233 (69%), Gaps = 9/233 (3%)
Query: 98 KLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIE 157
K P V +D+ T + +D GFE + +TY DIGGLK++LQ++RE IE
Sbjct: 161 KTEPKGPVVIDETTKVVY------RDRPAKGFERFGKAGITYEDIGGLKEELQKVREVIE 214
Query: 158 LPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGE 217
LPL++PELF+ +GI+PPKGVLLYGPPG GKTL+AKA+A+E+ A+F + G E++ K+ GE
Sbjct: 215 LPLRYPELFQRLGIEPPKGVLLYGPPGTGKTLIAKAVANEIGASFFTINGPEIMSKFYGE 274
Query: 218 GARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPR 277
+ + E+FE AKE AP+IIFIDEID+I KR + T ER R + QLL MDG + R
Sbjct: 275 SEQRLREIFEEAKENAPSIIFIDEIDSIAPKREEVTGEVER---RVVAQLLTLMDGLEER 331
Query: 278 GNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK 330
G V VI ATNR D +DPAL RPGRFDR IE+ +PD EGR EI ++HTR M L+
Sbjct: 332 GQVIVIGATNRIDAVDPALRRPGRFDREIEIGVPDREGRYEIFQIHTRNMPLE 384
>sp|O67077|FTSH_AQUAE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446574|pir||B70381 cell
division protein FtsH - Aquifex aeolicus
>gi|2983448|gb|AAC07029.1| (AE000714) cell division
protein FtsH [Aquifex aeolicus]
Length = 634
Score = 256 bits (646), Expect = 4e-67
Identities = 138/257 (53%), Positives = 178/257 (68%), Gaps = 4/257 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+P VT+ D+ G+++ +E++E IE LK P F+++G PPKGVLLYG PG GKTL+AK
Sbjct: 148 EKPKVTFKDVAGIEEVKEEVKEIIEY-LKDPVKFQKLGGRPPKGVLLYGEPGVGKTLLAK 206
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIG-AKRMD 251
A+A E + FI V GS+ V ++G GA V +LFE AK+ AP IIFIDEIDA+G A+
Sbjct: 207 AIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLFETAKKHAPCIIFIDEIDAVGRARGAI 266
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
GG E +TL QLL EMDGFD + VIAATNRPDILDPALLRPGRFDR I +P P
Sbjct: 267 PVGGGHDEREQTLNQLLVEMDGFDTSDGIIVIAATNRPDILDPALLRPGRFDRQIFIPKP 326
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D GR EILKVH R KL K+VDL +A T G +GADL+ + EA + A R+ + +T
Sbjct: 327 DVRGRYEILKVHARNKKLAKDVDLEFVARATPGFTGADLENLLNEAALLAARKGKEEITM 386
Query: 371 EDFLKAVDKV-LGNERK 386
E+ +A+D++ +G ERK
Sbjct: 387 EEIEEALDRITMGLERK 403
>pir||A69086 cell division control protein Cdc48 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622767|gb|AAB86112.1| (AE000923) cell division
control protein Cdc48 [Methanobacterium
thermoautotrophicum]
Length = 732
Score = 250 bits (633), Expect = 1e-65
Identities = 146/321 (45%), Positives = 204/321 (63%), Gaps = 11/321 (3%)
Query: 63 FAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSK 122
F G +E L + A+ R + R+ P I+ D+ P + T A +
Sbjct: 407 FVGADLESLCKESAM-------RVLRRVLPEIKADEEIPKEVLKKMVVTRADFKDALKEI 459
Query: 123 DPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGP 182
P+ L +++ PNV+++DIGGL+ QELREA+E PLK+P+ F++ GI PPKG+LL+G
Sbjct: 460 QPSALREVLVQVPNVSWDDIGGLEGAKQELREAVEWPLKYPDRFKKFGIRPPKGILLHGS 519
Query: 183 PGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEI 242
PG GKTL+AKA+A+E A FI V G EL+ K++GE + V E+F A++ APT+IF DEI
Sbjct: 520 PGTGKTLLAKAVANESQANFIAVKGPELLSKWVGESEKGVREVFRKARQTAPTVIFFDEI 579
Query: 243 DAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRF 302
D+I + R +T R + QLL E+DG + +V VIAATNRPDILDPALLRPGRF
Sbjct: 580 DSIASVR-SGSTADSGVTQRVVNQLLTEIDGLEELQDVAVIAATNRPDILDPALLRPGRF 638
Query: 303 DRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAI 361
DR ++V PD E RL I +VHT+ M L +VDL +AE TEG GAD++A+ EA M +
Sbjct: 639 DRHVKVEDPDKEARLAIFRVHTKDMPLADDVDLEKLAEKTEGYVGADIEAVCREAAMLTL 698
Query: 362 RER--RTYVTQEDFLKAVDKV 380
R+ V+ + FL+A++KV
Sbjct: 699 RDNMDAEEVSMKYFLEAMEKV 719
Score = 249 bits (628), Expect = 6e-65
Identities = 140/274 (51%), Positives = 184/274 (67%), Gaps = 21/274 (7%)
Query: 136 NVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALA 195
+VTY DIGGLK++++++RE IE+PLK PELFE +GI PPKGVL++GPPG GKTL+AKA+A
Sbjct: 201 DVTYEDIGGLKEEVKKVREMIEIPLKRPELFERLGITPPKGVLMHGPPGTGKTLLAKAVA 260
Query: 196 HEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTG 255
+E +A FI + G E++ KY+G + E FE A+E AP+IIFIDEIDAI KR E
Sbjct: 261 NESDAHFIAINGPEIMSKYVGGSEERLREFFEEAEENAPSIIFIDEIDAIAPKR--EDVS 318
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
GE E R + QLL MDG RG V VI ATNRPD LDPAL RPGRFDR IE+ +PD E
Sbjct: 319 GEVE-RRIVAQLLTLMDGLKSRGQVVVIGATNRPDALDPALRRPGRFDREIEIGVPDREE 377
Query: 316 RLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRE----------- 363
R EIL++HTR M L +VDL +AEIT G GADL+++ E+ M +R
Sbjct: 378 RKEILQIHTRGMPLADDVDLDELAEITHGFVGADLESLCKESAMRVLRRVLPEIKADEEI 437
Query: 364 -----RRTYVTQEDFLKAVDKVLGNE-RKLLQQI 391
++ VT+ DF A+ ++ + R++L Q+
Sbjct: 438 PKEVLKKMVVTRADFKDALKEIQPSALREVLVQV 471
>pir||E72358 cell division protein FtsH - Thermotoga maritima (strain MSB8)
>gi|4981098|gb|AAD35665.1|AE001733_2 (AE001733) cell
division protein FtsH [Thermotoga maritima]
Length = 610
Score = 243 bits (614), Expect = 3e-63
Identities = 127/260 (48%), Positives = 172/260 (65%), Gaps = 2/260 (0%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+GG ++ ++EL+E +E LK P F +G PKG+LL GPPG GKTL+A+A+A
Sbjct: 158 VTFKDVGGAEEAIEELKEVVEF-LKDPSKFNRIGARMPKGILLVGPPGTGKTLLARAVAG 216
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E N F + GS+ V ++G GA V +LF AK AP I+FIDEIDA+G R GG
Sbjct: 217 EANVPFFHISGSDFVELFVGVGAARVRDLFAQAKAHAPCIVFIDEIDAVGRHRGAGLGGG 276
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGFD + + V+AATNRPDILDPALLRPGRFD+ I V PD GR
Sbjct: 277 HDEREQTLNQLLVEMDGFDSKEGIIVMAATNRPDILDPALLRPGRFDKKIVVDPPDMLGR 336
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
+IL++HTR L ++V+L +IA+ T G GADL+ + EA + A RE R +T +DF +
Sbjct: 337 KKILEIHTRNKPLAEDVNLEIIAKRTPGFVGADLENLVNEAALLAAREGRDKITMKDFEE 396
Query: 376 AVDKVLGNERKLLQQITSHE 395
A+D+V+ + + I+ E
Sbjct: 397 AIDRVIAGPARKSKLISPKE 416
>gb|AAG20864.1| (AE005154) cell division cycle protein; Cdc48d [Halobacterium sp.
NRC-1]
Length = 737
Score = 239 bits (603), Expect = 5e-62
Identities = 123/232 (53%), Positives = 165/232 (71%), Gaps = 4/232 (1%)
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P +TY DIGGL +L+++RE IELP++HPELF +GI+PPKGVLL+GPPG GKTL+AKA+
Sbjct: 188 PALTYEDIGGLDDELEQVREMIELPMRHPELFGTLGIEPPKGVLLHGPPGTGKTLIAKAV 247
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
A+E++A F + G E++ KY GE + ++FE A+E AP I+FIDE+D+I KR D +
Sbjct: 248 ANEIDAHFQTISGPEIMSKYYGESEEQLRDVFEEAEENAPAIVFIDELDSIAPKREDVSG 307
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
ER R + QLL+ MDG + RG + VI TNR D +DPAL RPGRFDR IE+ +PD +
Sbjct: 308 DVER---RVVAQLLSLMDGLEERGQLTVIGTTNRVDAVDPALRRPGRFDREIEIGVPDHD 364
Query: 315 GRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERR 365
GR +IL++HTR M L VDL AE T+G GADL+ + E+ M A+R R
Sbjct: 365 GREKILQIHTRGMPLGDGVDLDRYAENTQGFVGADLENLVKESAMHALRRIR 416
Score = 224 bits (566), Expect = 1e-57
Identities = 116/275 (42%), Positives = 176/275 (63%), Gaps = 4/275 (1%)
Query: 123 DPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGP 182
+P+ L +E P+VT++ +GGL + L+E ++ PL+H + +E+V ++P KGVLLYGP
Sbjct: 449 EPSALREVFVEVPDVTWDHVGGLDDAKERLQETVQWPLEHADAYEQVALEPAKGVLLYGP 508
Query: 183 PGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEI 242
PG GKTL+AKA+A+E N+ FI + G EL KY+GE R V E+F A+E APT++F DEI
Sbjct: 509 PGTGKTLLAKAVANEANSNFISIKGPELFNKYVGESERGVREVFSKARENAPTVVFFDEI 568
Query: 243 DAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRF 302
DAI ++R + G R + QLL E+DG + ++ VIA TNRPD++D ALLRPGR
Sbjct: 569 DAIASER-GQGVGDSNVGERVVSQLLTELDGLEELEDIVVIATTNRPDLIDDALLRPGRL 627
Query: 303 DRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAI 361
DR + V PD R EI ++HT L ++VD+ + E T+G GAD++A+ EA A+
Sbjct: 628 DRHVAVDEPDEAARREIFEIHTEDKPLAEDVDVDELVERTDGYVGADIEAVCREAATVAV 687
Query: 362 RE--RRTYVTQEDFLKAVDKVLGNERKLLQQITSH 394
RE R T + + ++ + + + L+++ S+
Sbjct: 688 REYVRATASAESANVDEIELSIEHFEQALEEVDSN 722
>emb|CAB51029.1| (AJ243808) metalloprotease FtsH [Bradyrhizobium japonicum]
Length = 640
Score = 238 bits (602), Expect = 6e-62
Identities = 130/263 (49%), Positives = 173/263 (65%), Gaps = 3/263 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G+ + Q+L+E +E L+ P F+ +G P+GVLL GPPG GKTL+A+A+A
Sbjct: 153 VTFEDVAGVDEAKQDLQEIVEF-LRDPGKFQRLGGRIPRGVLLVGPPGTGKTLIARAVAG 211
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E N F + GS+ V ++G GA V ++FE AK+ AP IIFIDEIDA+G R GG
Sbjct: 212 EANVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRHRGAGLGGG 271
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF+ V +IAATNRPD+LDPALLRPGRFDR + VP PD GR
Sbjct: 272 NDEREQTLNQLLVEMDGFEANEGVILIAATNRPDVLDPALLRPGRFDRQVVVPNPDVVGR 331
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
+ILKVH R++ L +++L+ IA T G SGADL + EA + A R + VTQ +F +
Sbjct: 332 EQILKVHVRKVPLAPDINLKTIARGTPGFSGADLMNLVNEAALTAARRNKRMVTQAEFEE 391
Query: 376 AVDKV-LGNERKLLQQITSHEII 397
A DKV +G ERK L +++
Sbjct: 392 AKDKVMMGAERKSLVMTEEEKLL 414
>pir||F72009 cell division protein FtsH, probable CP0857 [imported] -
Chlamydophila pneumoniae (strains CWL029 and AR39)
>gi|4377327|gb|AAD19135.1| (AE001680) ATP-dependent zinc
protease [Chlamydophila pneumoniae CWL029]
>gi|7189768|gb|AAF38646.1| (AE002244) cell division
protein FtsH, putative [Chlamydophila pneumoniae AR39]
>gi|8979371|dbj|BAA99205.1| (AP002548) ATP-dependent
zinc protease [Chlamydophila pneumoniae J138]
Length = 910
Score = 238 bits (600), Expect = 1e-61
Identities = 130/255 (50%), Positives = 169/255 (65%), Gaps = 3/255 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G+++ +EL E ++ LK+P F +G PKGVLL GPPG GKTL+AKA++
Sbjct: 424 VTFADVAGIEEAKEELIEIVDF-LKNPNKFTSLGGRIPKGVLLIGPPGTGKTLIAKAVSG 482
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E + F + GS+ V ++G GA + ++FE AK AP IIFIDEIDA+G R GG
Sbjct: 483 EADRPFFSIAGSDFVEMFVGVGASRIRDMFEQAKRNAPCIIFIDEIDAVGRHRGAGIGGG 542
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF V ++AATNRPD+LD ALLRPGRFDR + + LPD +GR
Sbjct: 543 HDEREQTLNQLLVEMDGFGTNEGVILMAATNRPDVLDKALLRPGRFDRRVVMNLPDIKGR 602
Query: 317 LEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
EIL VH +R+KL VDL +A T GASGADL+ + EA + A R+ RT VT D +
Sbjct: 603 FEILMVHAKRIKLDPTVDLMAVARSTPGASGADLENLLNEAALLAARKDRTAVTAVDVAE 662
Query: 376 AVDKVL-GNERKLLQ 389
A DKVL G ER+ L+
Sbjct: 663 ARDKVLYGKERRSLE 677
>pir||T48355 transitional endoplasmic reticulum ATPase - Arabidopsis thaliana
>gi|7378614|emb|CAB83290.1| (AL162751) transitional
endoplasmic reticulum ATPase [Arabidopsis thaliana]
Length = 843
Score = 237 bits (598), Expect = 2e-61
Identities = 122/237 (51%), Positives = 169/237 (70%), Gaps = 4/237 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V Y+D+GG++KQ+ ++RE +ELPL+HP+LF+ +G+ PPKG+LLYGPPG GKTL+A+A+A+
Sbjct: 237 VGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVAN 296
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E A F + G E++ K GE + + FE A++ AP+IIFIDEID+I KR E T G
Sbjct: 297 ETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKR--EKTNG 354
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E E R + QLL MDG R +V V+ ATNRP+ +DPAL R GRFDR I++ +PD GR
Sbjct: 355 EVE-RRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGR 413
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
LE+L++HT+ MKL ++VDL I++ T G GADL A+ TEA + IRE+ + ED
Sbjct: 414 LEVLRIHTKNMKLAEDVDLERISKDTHGYVGADLAALCTEAALQCIREKMDVIDLED 470
Score = 236 bits (597), Expect = 2e-61
Identities = 122/270 (45%), Positives = 173/270 (63%), Gaps = 13/270 (4%)
Query: 121 SKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLY 180
+ +P+ L V+E PNV++ DIGGL+ +EL+E ++ P++HPE FE+ G+ P KGVL Y
Sbjct: 494 NSNPSALRETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFY 553
Query: 181 GPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFID 240
GPPGCGKTL+AKA+A+E A FI V G EL+ + GE V E+F+ A++ AP ++F D
Sbjct: 554 GPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFD 613
Query: 241 EIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPG 300
E+D+I +R + +R L QLL EMDG + + V +I ATNRPDI+D ALLRPG
Sbjct: 614 ELDSIATQRGNSAGDAGGAADRVLNQLLTEMDGMNAKKTVFIIGATNRPDIIDSALLRPG 673
Query: 301 RFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMF 359
R D+LI +PLPD + RL I K R+ + K+VD+ +A+ T+G SGAD+ I A +
Sbjct: 674 RLDQLIYIPLPDEDSRLNIFKACLRKSPVAKDVDVTALAKYTQGFSGADITEICQRACKY 733
Query: 360 AIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
AIRE ++K + NER+ Q
Sbjct: 734 AIREN------------IEKDIENERRRSQ 751
>gi|6320077 microsomal ATPase; Cdc48p [Saccharomyces cerevisiae]
>gi|1705679|sp|P25694|CC48_YEAST CELL DIVISION CONTROL
PROTEIN 48 >gi|2118116|pir||S67669 transitional
endoplasmic reticulum ATPase [validated] - yeast
(Saccharomyces cerevisiae) >gi|1431189|emb|CAA98694.1|
(Z74174) ORF YDL126c [Saccharomyces cerevisiae]
>gi|1449400|emb|CAA40276.1| (X56956) CDC48p
[Saccharomyces cerevisiae]
Length = 835
Score = 236 bits (596), Expect = 3e-61
Identities = 121/237 (51%), Positives = 166/237 (69%), Gaps = 4/237 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V Y+DIGG +KQ+ ++RE +ELPL+HP+LF+ +GI PP+GVL+YGPPG GKTLMA+A+A+
Sbjct: 211 VGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVAN 270
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E A F + G E++ K GE + + FE A++ AP IIFIDEID+I KR + T G
Sbjct: 271 ETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKR--DKTNG 328
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E E R + QLL MDG R NV VIAATNRP+ +DPAL R GRFDR +++ +PD GR
Sbjct: 329 EVE-RRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGR 387
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
LE+L++HT+ MKL +VDL +A T G GAD+ ++ +EA M IRE+ + ++
Sbjct: 388 LEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDE 444
Score = 224 bits (564), Expect = 2e-57
Identities = 121/281 (43%), Positives = 173/281 (61%), Gaps = 2/281 (0%)
Query: 111 TMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVG 170
TM + +P+ L V+E NVT++D+GGL + +EL+E +E P+ HP+ + + G
Sbjct: 458 TMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFG 517
Query: 171 IDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAK 230
+ P KGVL YGPPG GKTL+AKA+A EV+A FI V G EL+ + GE + ++F+ A+
Sbjct: 518 LSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKAR 577
Query: 231 EKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPD 290
APT++F+DE+D+I R +R + QLL EMDG + + NV VI ATNRPD
Sbjct: 578 AAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPD 637
Query: 291 ILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADL 349
+DPA+LRPGR D+LI VPLPD RL IL R+ L+ ++L IA+ T+G SGADL
Sbjct: 638 QIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADL 697
Query: 350 KAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQ 390
I A +AI++ Q + K V KV G + ++ +
Sbjct: 698 LYIVQRAAKYAIKDSIEAHRQHEAEKEV-KVEGEDVEMTDE 737
>pir||F81725 cell division protein FtsH, probable TC0229 [imported] - Chlamydia
muridarum (strain Nigg) >gi|7190269|gb|AAF39101.1|
(AE002290) cell division protein FtsH, putative
[Chlamydia muridarum]
Length = 920
Score = 235 bits (593), Expect = 7e-61
Identities = 129/255 (50%), Positives = 168/255 (65%), Gaps = 3/255 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G+++ +EL E ++ LK+P F +G PKG+LL G PG GKTL+AKA+A
Sbjct: 431 VTFADVAGIEEAKEELVEIVDF-LKNPTKFTSLGGRIPKGILLIGAPGTGKTLIAKAVAG 489
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E + F + GS+ V ++G GA + ++FE AK AP IIFIDEIDA+G R GG
Sbjct: 490 EADRPFFSIAGSDFVEMFVGVGASRIRDMFEQAKRNAPCIIFIDEIDAVGRHRGAGIGGG 549
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF V ++AATNRPD+LD ALLRPGRFDR + V LPD +GR
Sbjct: 550 HDEREQTLNQLLVEMDGFGTNEGVILMAATNRPDVLDKALLRPGRFDRRVVVNLPDIKGR 609
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
EIL VH +R+KL VDL +A T GASGADL+ + EA + A R+ RT VT + +
Sbjct: 610 FEILSVHAKRIKLDPTVDLMAVARSTPGASGADLENLLNEAALLAARKDRTAVTAVEVAE 669
Query: 376 AVDKVL-GNERKLLQ 389
A DKVL G ER+ L+
Sbjct: 670 ARDKVLYGKERRSLE 684
>pir||D71463 probable ATP-dependent zinc proteinase - Chlamydia trachomatis
(serotype D, strain UW3/Cx) >gi|3329313|gb|AAC68438.1|
(AE001357) ATP-dependent zinc protease [Chlamydia
trachomatis]
Length = 913
Score = 235 bits (592), Expect = 1e-60
Identities = 129/255 (50%), Positives = 168/255 (65%), Gaps = 3/255 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G+++ +EL E ++ LK+P F +G PKG+LL G PG GKTL+AKA+A
Sbjct: 423 VTFADVAGIEEAKEELVEIVDF-LKNPTKFTSLGGRIPKGILLIGAPGTGKTLIAKAVAG 481
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E + F + GS+ V ++G GA + ++FE AK AP IIFIDEIDA+G R GG
Sbjct: 482 EADRPFFSIAGSDFVEMFVGVGASRIRDMFEQAKRNAPCIIFIDEIDAVGRHRGAGIGGG 541
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF V ++AATNRPD+LD ALLRPGRFDR + V LPD +GR
Sbjct: 542 HDEREQTLNQLLVEMDGFGTNEGVILMAATNRPDVLDKALLRPGRFDRRVVVNLPDIKGR 601
Query: 317 LEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
EIL VH +R+KL VDL +A T GASGADL+ + EA + A R+ RT VT + +
Sbjct: 602 FEILAVHAKRIKLDPTVDLMAVARSTPGASGADLENLLNEAALLAARKDRTAVTAVEVAE 661
Query: 376 AVDKVL-GNERKLLQ 389
A DKVL G ER+ L+
Sbjct: 662 ARDKVLYGKERRSLE 676
>pir||T36330 cell division protein ftsH2 - Streptomyces coelicolor
>gi|4808343|emb|CAB42757.1| (AL049841) cell division
protein ftsH homolog [Streptomyces coelicolor A3(2)]
Length = 668
Score = 235 bits (592), Expect = 1e-60
Identities = 125/264 (47%), Positives = 166/264 (62%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P T++D+ G + ++EL E E L+ P F+ VG PKGVLLYGPPG GKTL+A+
Sbjct: 153 DTPKTTFSDVAGSDEAVEELHEIKEF-LQEPAKFQAVGAKIPKGVLLYGPPGTGKTLLAR 211
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V +LFE AK AP I+F+DEIDA+G R
Sbjct: 212 AVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFEQAKANAPAIVFVDEIDAVGRHRGAG 271
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGFD +G V +IAATNRPDILDPALLRPGRFDR I V PD
Sbjct: 272 LGGGHDEREQTLNQLLVEMDGFDVKGGVILIAATNRPDILDPALLRPGRFDRQIAVDRPD 331
Query: 313 FEGRLEILKVHTR-RMKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+GRLEILKVH + + +VDL +A T G +GADL + EA + R + +
Sbjct: 332 MQGRLEILKVHQKGKPVAPDVDLSAVARRTPGMTGADLANVLNEAALLTARSDQKLIDNH 391
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
+A+D+V+ +K + ++ E
Sbjct: 392 MLDEAIDRVVAGPQKRTRIMSDKE 415
>gi|11467752 hypothetical chloroplast RF25 [Guillardia theta]
>gi|6016057|sp|O78516|FTSH_GUITH CELL DIVISION PROTEIN
FTSH HOMOLOG >gi|3603077|gb|AAC35738.1| (AF041468)
hypothetical chloroplast RF25 [Guillardia theta]
Length = 631
Score = 234 bits (591), Expect = 1e-60
Identities = 127/271 (46%), Positives = 170/271 (61%), Gaps = 3/271 (1%)
Query: 129 FEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKT 188
F++ + VT+ND+ G+ + +E E + LK PE F VG PKGVLL GPPG GKT
Sbjct: 162 FQMEAKTGVTFNDVAGVDEAKEEFEEVVSF-LKKPERFTAVGAKIPKGVLLVGPPGTGKT 220
Query: 189 LMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAK 248
L+AKA+A E F + GSE V ++G GA V +LF+ AKE +P I+FIDEIDA+G +
Sbjct: 221 LLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENSPCIVFIDEIDAVGRQ 280
Query: 249 RMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEV 308
R GG E +TL QLL EMDGF+ + +IAATNR D+LD ALLRPGRFDR + V
Sbjct: 281 RGTGIGGGNDEREQTLNQLLTEMDGFEGNTGIIIIAATNRVDVLDAALLRPGRFDRQVTV 340
Query: 309 PLPDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTY 367
+PD +GRLEIL VH R KL ++ L +IA+ T G SGADL + EA + R R+
Sbjct: 341 DVPDVKGRLEILNVHARNKKLDLSISLELIAKRTPGFSGADLANLLNEAAILTARRRKKQ 400
Query: 368 VTQEDFLKAVDKVL-GNERKLLQQITSHEII 397
+T + ++D+V+ G E K L + +I
Sbjct: 401 ITISEIDASIDRVIAGMEGKALVDSKTKRLI 431
>gi|11465793 hypothetical chloroplast ORF 25. [Porphyra purpurea]
>gi|1706926|sp|P51327|FTSH_PORPU CELL DIVISION PROTEIN
FTSH HOMOLOG >gi|2147534|pir||S73248 hypothetical
protein 25 - red alga (Porphyra purpurea) chloroplast
>gi|1276793|gb|AAC08213.1| (U38804) hypothetical
chloroplast ORF 25. [Porphyra purpurea]
Length = 628
Score = 234 bits (590), Expect = 2e-60
Identities = 127/276 (46%), Positives = 171/276 (61%), Gaps = 9/276 (3%)
Query: 129 FEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKT 188
F++ + V +ND+ G+++ +E +E + LK PE F VG PKGVLL GPPG GKT
Sbjct: 162 FQMEAKTGVVFNDVAGVEEAKEEFQEVVTF-LKQPESFTAVGAKIPKGVLLVGPPGTGKT 220
Query: 189 LMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAK 248
L+AKA+A E F + GSE V ++G GA V +LF+ AK+ AP I+FIDEIDA+G +
Sbjct: 221 LLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKDNAPCIVFIDEIDAVGRQ 280
Query: 249 RMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEV 308
R GG E +TL QLL EMDGF+ V VIAATNR DILD ALLRPGRFDR + V
Sbjct: 281 RGTGVGGGNDEREQTLNQLLTEMDGFEGNTGVIVIAATNRADILDSALLRPGRFDRQVSV 340
Query: 309 PLPDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTY 367
+PDF GRL IL+VH + K+++ V L IA T G SGADL + EA + R R++
Sbjct: 341 DVPDFRGRLAILEVHAKNKKMESKVSLETIARRTPGFSGADLANLLNEAAILTARRRKSA 400
Query: 368 VTQEDFLKAVDKVLGN-------ERKLLQQITSHEI 396
+T + ++D+V+ + K + I HE+
Sbjct: 401 MTMSEIDTSIDRVVAGLEGTPLIDSKSKRLIAYHEV 436
>sp|P28691|FTSH_ECOLI CELL DIVISION PROTEIN FTSH >gi|421034|pir||S35109 cell division
protein ftsH (EC 3.4.24.-) - Escherichia coli
>gi|146028|gb|AAA23813.1| (M83138) ftsH [Escherichia
coli] >gi|606116|gb|AAA57979.1| (U18997) CG Site No. 735
[Escherichia coli] >gi|1789568|gb|AAC76210.1| (AE000398)
degrades sigma32, integral membrane peptidase, cell
division protein [Escherichia coli K12]
Length = 644
Score = 233 bits (588), Expect = 3e-60
Identities = 125/251 (49%), Positives = 166/251 (65%), Gaps = 3/251 (1%)
Query: 138 TYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHE 197
T+ D+ G + +E+ E +E L+ P F+++G PKGVL+ GPPG GKTL+AKA+A E
Sbjct: 150 TFADVAGCDEAKEEVAELVEY-LREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGE 208
Query: 198 VNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGE 257
F + GS+ V ++G GA V ++FE AK+ AP IIFIDEIDA+G +R GG
Sbjct: 209 AKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGH 268
Query: 258 REVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRL 317
E +TL Q+L EMDGF+ + VIAATNRPD+LDPALLRPGRFDR + V LPD GR
Sbjct: 269 DEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGRE 328
Query: 318 EILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKA 376
+ILKVH RR+ L ++D +IA T G SGADL + EA +FA R + V+ +F KA
Sbjct: 329 QILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKA 388
Query: 377 VDKV-LGNERK 386
DK+ +G ER+
Sbjct: 389 KDKIMMGAERR 399
>gb|AAA97508.1| (U01376) ATP-binding protein [Escherichia coli]
Length = 647
Score = 233 bits (588), Expect = 3e-60
Identities = 125/251 (49%), Positives = 166/251 (65%), Gaps = 3/251 (1%)
Query: 138 TYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHE 197
T+ D+ G + +E+ E +E L+ P F+++G PKGVL+ GPPG GKTL+AKA+A E
Sbjct: 153 TFADVAGCDEAKEEVAELVEY-LREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGE 211
Query: 198 VNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGE 257
F + GS+ V ++G GA V ++FE AK+ AP IIFIDEIDA+G +R GG
Sbjct: 212 AKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGH 271
Query: 258 REVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRL 317
E +TL Q+L EMDGF+ + VIAATNRPD+LDPALLRPGRFDR + V LPD GR
Sbjct: 272 DEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGRE 331
Query: 318 EILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKA 376
+ILKVH RR+ L ++D +IA T G SGADL + EA +FA R + V+ +F KA
Sbjct: 332 QILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKA 391
Query: 377 VDKV-LGNERK 386
DK+ +G ER+
Sbjct: 392 KDKIMMGAERR 402
>gb|AAC32257.1| (AF037269) cell division protein [Mycobacterium smegmatis]
Length = 769
Score = 233 bits (588), Expect = 3e-60
Identities = 125/264 (47%), Positives = 169/264 (63%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P T+ D+ G+ + ++EL E + L++P ++ +G PKGVLLYGPPG GKTL+A+
Sbjct: 156 DMPKTTFADVAGVDEAVEELYEIKDF-LQNPSRYQALGAKIPKGVLLYGPPGTGKTLLAR 214
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V +LFE AK+ +P IIF+DEIDA+G +R
Sbjct: 215 AVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAG 274
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF R V +IAATNRPDILDPALLRPGRFDR I V PD
Sbjct: 275 LGGGHDEREQTLNQLLVEMDGFGDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSNPD 334
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR +LKVH++ + + DL +A+ T G SGADL + EA + RE T +T
Sbjct: 335 LAGRRAVLKVHSQGKPIAPDADLDGLAKRTVGMSGADLANVINEAALLTARENGTVITGP 394
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
+AVD+V+G R+ + I+ HE
Sbjct: 395 ALEEAVDRVVGGPRRKSRIISEHE 418
>gi|10946660 spermatogenesis associated factor [Mus musculus]
>gi|4105619|gb|AAD02481.1| (AF049099) SPAF [Mus
musculus]
Length = 892
Score = 233 bits (587), Expect = 4e-60
Identities = 134/344 (38%), Positives = 205/344 (58%), Gaps = 17/344 (4%)
Query: 27 RQLELQVRMLEADKERLERELSRL-----RSEMSRL-RQPPAFAGTVIEVLDDDRAIVQN 80
+++E+ + + + L++ L R+ ++E+ RL + G ++ L ++ +
Sbjct: 516 KEIEIGIPNAQDRLDILQKLLRRVPHLLTKAELLRLANNAHGYVGADLKALCNEAGL--- 572
Query: 81 YNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYN 140
+ R V+R P + K+ ++ L+ + ++ PS+ I+ PNV+++
Sbjct: 573 -HALRRVLRKQPNLPDSKVAGMVKITLNDFLQGMNDIRPSAMREVA-----IDVPNVSWS 626
Query: 141 DIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
DIGGL+ +L++A+E PLKHP+ F +GI PPKGVLLYGPPGC KT++AKALA+E
Sbjct: 627 DIGGLENIKLKLKQAVEWPLKHPKSFNRMGIQPPKGVLLYGPPGCSKTMIAKALANESGL 686
Query: 201 TFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREV 260
F+ + G EL+ KY+GE R V E+F A+ AP+IIF DE+DA+ +R ++G
Sbjct: 687 NFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDELDALAVER-GSSSGAGNVA 745
Query: 261 NRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEIL 320
+R L QLL EMDG + NV V+AATNRPD +D AL+RPGR DR+I VPLPD R EIL
Sbjct: 746 DRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIL 805
Query: 321 KVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRE 363
+ M + N VDL + T+ SGA++ A+ EA + A+ E
Sbjct: 806 NLQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEAALLALEE 849
Score = 193 bits (486), Expect = 3e-48
Identities = 105/228 (46%), Positives = 147/228 (64%), Gaps = 2/228 (0%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VTY+ IGGL QL+ +RE IELPLK PELF+ GI P+G+LLYGPPG GKT++A+A+A+
Sbjct: 349 VTYDMIGGLNSQLKAIREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVAN 408
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
EV A + G E++ K+ GE + ++F A + P+IIFIDE+DA+ KR +
Sbjct: 409 EVGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREGAQSEV 468
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E+ V +L+ L+ + G V V+ ATNRP LD AL RPGRFD+ IE+ +P+ + R
Sbjct: 469 EKRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQDR 528
Query: 317 LEILKVHTRRMK--LKNVDLRVIAEITEGASGADLKAIATEAGMFAIR 362
L+IL+ RR+ L +L +A G GADLKA+ EAG+ A+R
Sbjct: 529 LDILQKLLRRVPHLLTKAELLRLANNAHGYVGADLKALCNEAGLHALR 576
>pir||G81315 membrane bound zinc metallopeptidase (EC 3.4.24.-) Cj1116c
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968550|emb|CAB73371.1| (AL139077) membrane bound
zinc metallopeptidase [Campylobacter jejuni]
Length = 645
Score = 233 bits (587), Expect = 4e-60
Identities = 125/266 (46%), Positives = 176/266 (65%), Gaps = 4/266 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+P V ++D+ G+++ +E++E ++ LK+PE + ++G PKG+LL GPPG GKTL+AK
Sbjct: 171 EKPKVKFSDVAGVEEAKEEVKEIVDF-LKYPERYIKLGAKIPKGLLLVGPPGTGKTLLAK 229
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR-MD 251
A+A E + F V GS + ++G GA V +LFE AK++AP I+FIDEIDAIG R
Sbjct: 230 AVAGEADVPFFSVSGSSFIEMFVGVGASRVRDLFENAKKEAPAIVFIDEIDAIGKSRAAS 289
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGN-VKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
GG E +TL QLLAEMDGF + V V+AATNRP++LD ALLRPGRFDR + V
Sbjct: 290 GMMGGNDEREQTLNQLLAEMDGFGTESSPVIVLAATNRPEVLDAALLRPGRFDRQVLVDK 349
Query: 311 PDFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
PDF+GR +ILKVH + +K+ V + IA +T G +GADL I EA + A R+ + YV
Sbjct: 350 PDFKGRCDILKVHMKDVKISPKVKVEDIARLTAGLAGADLANIINEAALLAGRDSKKYVE 409
Query: 370 QEDFLKAVDKVLGNERKLLQQITSHE 395
Q D ++AV++ + K ++I E
Sbjct: 410 QNDLVEAVERAIAGLEKKSRRINEKE 435
>sp|P71408|FTSH_HELPY CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446580|pir||E64653 cell
division protein - Helicobacter pylori (strain 26695)
>gi|2314219|gb|AAD08115.1| (AE000614) cell division
protein (ftsH) [Helicobacter pylori 26695]
Length = 632
Score = 232 bits (586), Expect = 5e-60
Identities = 129/266 (48%), Positives = 176/266 (65%), Gaps = 4/266 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+PNV +ND+ G ++ +E+ E ++ LK+PE + +G PKGVLL GPPG GKTL+AK
Sbjct: 163 EKPNVRFNDMAGNEEAKEEVVEIVDF-LKYPERYANLGAKIPKGVLLVGPPGTGKTLLAK 221
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR-MD 251
A+A E + F + GS + ++G GA V +LFE AK++AP+IIFIDEIDAIG R
Sbjct: 222 AVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDLFETAKKQAPSIIFIDEIDAIGKSRAAG 281
Query: 252 ETTGGEREVNRTLMQLLAEMDGF-DPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
G E +TL QLLAEMDGF V V+AATNRP+ILDPAL+RPGRFDR + V
Sbjct: 282 GVVSGNDEREQTLNQLLAEMDGFGSENAPVIVLAATNRPEILDPALMRPGRFDRQVLVDK 341
Query: 311 PDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
PDF GR+EILKVH + +KL N V+L+ +A++T G +GADL I EA + A R + V
Sbjct: 342 PDFNGRVEILKVHIKGVKLANDVNLQEVAKLTAGLAGADLANIINEAALLAGRNNQKEVR 401
Query: 370 QEDFLKAVDKVLGNERKLLQQITSHE 395
Q+ +AV++ + K ++I+ E
Sbjct: 402 QQHLKEAVERGIAGLEKKSRRISPKE 427
>pir||D70198 cell division protein (ftsH) homolog - Lyme disease spirochete
>gi|2688712|gb|AAC67120.1| (AE001177) cell division
protein (ftsH) [Borrelia burgdorferi]
Length = 639
Score = 232 bits (586), Expect = 5e-60
Identities = 124/260 (47%), Positives = 168/260 (63%), Gaps = 2/260 (0%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+T+ D+ G ++ QELRE +E LK+P+ FE++G PKGVLL G PG GKTL+AKA+A
Sbjct: 169 ITFKDVAGQEEVKQELREVVEF-LKNPKKFEKIGAKIPKGVLLVGSPGTGKTLLAKAVAG 227
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E +F + GS+ V ++G GA V +LF+ A++ +P IIFIDE+DA+G R GG
Sbjct: 228 EAGVSFFHMSGSDFVEMFVGVGASRVRDLFDNARKNSPCIIFIDELDAVGRSRGAGLGGG 287
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF NV V+AATNRPD+LD ALLRPGRFDR + V LPD + R
Sbjct: 288 HDEREQTLNQLLVEMDGFGTHTNVIVMAATNRPDVLDSALLRPGRFDRQVTVSLPDIKER 347
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
IL +H+ + KL K+++L+VIA T GASGADL + E + A R + + +D +
Sbjct: 348 EAILNIHSLKTKLSKDINLQVIARATPGASGADLANLINEGALIAARNNQDEILMKDMEE 407
Query: 376 AVDKVLGNERKLLQQITSHE 395
A DK+L K IT +
Sbjct: 408 ARDKILMGVAKKSMTITDRQ 427
>sp|O32617|FTSH_HELFE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|11278958|pir||T47267 cell
cycle protein [imported] - Helicobacter felis
>gi|2660540|emb|CAA05102.1| (AJ001932) cell cycle
protein [Helicobacter felis]
Length = 638
Score = 231 bits (584), Expect = 8e-60
Identities = 129/266 (48%), Positives = 177/266 (66%), Gaps = 4/266 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+P V +ND+ G ++ +E+ E ++ LK+P+ + +G PKGVLL GPPG GKTL+AK
Sbjct: 169 EKPKVRFNDMAGNEEAKEEVVEIVDF-LKYPDRYASLGAKIPKGVLLVGPPGTGKTLLAK 227
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR-MD 251
A+A E + F + GS + ++G GA V +LF++AK++AP+IIFIDEIDAIG R
Sbjct: 228 AVAGEASVPFFSMGGSSFIEMFVGLGASRVRDLFDIAKKEAPSIIFIDEIDAIGKSRAAG 287
Query: 252 ETTGGEREVNRTLMQLLAEMDGF-DPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
G E +TL QLLAEMDGF V V+AATNRP+ILDPALLRPGRFDR + V
Sbjct: 288 GMISGNDEREQTLNQLLAEMDGFGSENAPVIVLAATNRPEILDPALLRPGRFDRQVLVDK 347
Query: 311 PDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
PDF+GR+EILKVH + +KL N VDL+ IA++T G +GADL I EA + A R + V
Sbjct: 348 PDFKGRVEILKVHIKPVKLANDVDLQEIAKLTAGLAGADLANIINEAALLAGRNNQKEVK 407
Query: 370 QEDFLKAVDKVLGNERKLLQQITSHE 395
Q+ +AV++ + K ++I+ E
Sbjct: 408 QQHLKEAVERGIAGLEKKSRRISPKE 433
>sp|Q9ZM66|FTSH_HELPJ CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446579|pir||D71941
ATP-dependent zinc metallopeptidase - Helicobacter
pylori (strain J99) >gi|4154882|gb|AAD05932.1|
(AE001471) ATP-DEPENDENT ZINC METALLOPEPTIDASE
[Helicobacter pylori J99]
Length = 632
Score = 231 bits (584), Expect = 8e-60
Identities = 129/266 (48%), Positives = 176/266 (65%), Gaps = 4/266 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+PNV +ND+ G ++ +E+ E ++ LK+PE + +G PKGVLL GPPG GKTL+AK
Sbjct: 163 EKPNVRFNDMAGNEEAKEEVVEIVDF-LKYPERYANLGAKIPKGVLLVGPPGTGKTLLAK 221
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR-MD 251
A+A E + F + GS + ++G GA V +LFE AK++AP+IIFIDEIDAIG R
Sbjct: 222 AVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDLFETAKKQAPSIIFIDEIDAIGKSRAAG 281
Query: 252 ETTGGEREVNRTLMQLLAEMDGF-DPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
G E +TL QLLAEMDGF V V+AATNRP+ILDPAL+RPGRFDR + V
Sbjct: 282 GMISGNDEREQTLNQLLAEMDGFGSENAPVIVLAATNRPEILDPALMRPGRFDRQVLVDK 341
Query: 311 PDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
PDF GR+EILKVH + +KL N V+L+ +A++T G +GADL I EA + A R + V
Sbjct: 342 PDFNGRVEILKVHIKGVKLANDVNLQEVAKLTAGLAGADLANIINEAALLAGRNNQKEVK 401
Query: 370 QEDFLKAVDKVLGNERKLLQQITSHE 395
Q+ +AV++ + K ++I+ E
Sbjct: 402 QQHLKEAVERGIAGLEKKSRRISPKE 427
>pir||E81948 probable ATP-dependent zinc metallopeptidase (EC 3.4.24.-) NMA1007
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7379709|emb|CAB84276.1| (AL162754) putative
ATP-dependent zinc metallopeptidase [Neisseria
meningitidis Z2491]
Length = 655
Score = 231 bits (583), Expect = 1e-59
Identities = 125/252 (49%), Positives = 166/252 (65%), Gaps = 3/252 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G + +E++E ++ LK P ++ +G P+G+LL G PG GKTL+AKA+A
Sbjct: 157 VTFADVAGCDEAKEEVQEIVDY-LKAPNRYQSLGGRVPRGILLAGSPGTGKTLLAKAIAG 215
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F + GS+ V ++G GA V ++FE AK+ AP IIFIDEIDA+G +R GG
Sbjct: 216 EAGVPFFSISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRQRGAGLGGG 275
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF+ V VIAATNRPD+LDPAL RPGRFDR + VPLPD GR
Sbjct: 276 NDEREQTLNQLLVEMDGFESNQTVIVIAATNRPDVLDPALQRPGRFDRQVVVPLPDIRGR 335
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
+IL VH++++ L K+VDL +A T G SGADL + EA +FA R + V Q DF
Sbjct: 336 EQILNVHSKKVPLDKSVDLLSLARGTPGFSGADLANLVNEAALFAGRRNKVKVDQSDFED 395
Query: 376 AVDKV-LGNERK 386
A DK+ +G ER+
Sbjct: 396 AKDKIYMGPERR 407
>pir||T31466 cell-division protein homolog ftsH - Heliobacillus mobilis
>gi|3820564|gb|AAC84037.1| (AF080002) ATP-dependent zinc
metallopeptidase FtsH [Heliobacillus mobilis]
Length = 601
Score = 231 bits (582), Expect = 1e-59
Identities = 123/264 (46%), Positives = 165/264 (61%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
++ VT+ D+ G + +EL+E ++ LKHP+ F E+G PKGVLL+GPPG GKTL+A+
Sbjct: 151 DKKKVTFEDVAGADEVKEELQEVVDF-LKHPKKFVELGAKIPKGVLLFGPPGTGKTLLAR 209
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V +LFE AK+ +P I+FIDEIDA+G +R
Sbjct: 210 AVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKNSPCIVFIDEIDAVGRQRGAG 269
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF + +IAATNRPDILDPALLRPGRFDR I V PD
Sbjct: 270 LGGGHDEREQTLNQLLVEMDGFSANEGIIIIAATNRPDILDPALLRPGRFDRQIVVDRPD 329
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR EIL VH + L + +DL V+A T G +GADL + EA + A R V
Sbjct: 330 IRGRKEILGVHVKGKPLDETIDLDVLARRTPGFTGADLANMVNEAALLAARRGTKKVGMH 389
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
+ A+++V+ K + I+ E
Sbjct: 390 EMEDAIERVIAGPEKKARVISEFE 413
>dbj|BAB13085.1| (AP001119) cell division protein ftsh [Buchnera sp. APS]
Length = 596
Score = 231 bits (582), Expect = 1e-59
Identities = 123/251 (49%), Positives = 168/251 (66%), Gaps = 3/251 (1%)
Query: 138 TYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHE 197
T+ D+ G + +E+ E +E LK P F+++G PKG+L+ GPPG GKTL+AKA+A E
Sbjct: 135 TFADVAGCDEAKEEVSELVEY-LKEPSRFQKLGGKIPKGILMVGPPGTGKTLLAKAIAGE 193
Query: 198 VNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGE 257
F + GS+ V ++G GA V ++FE +++ AP IIFIDEIDA+G +R GG
Sbjct: 194 AKVPFFTISGSDFVEMFVGVGASRVRDMFEHSRKSAPCIIFIDEIDAVGRQRGAGLGGGH 253
Query: 258 REVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRL 317
E +TL Q+L EMDGFD + +IAATNRPD+LDPALLRPGRFDR + V LPD GR
Sbjct: 254 DEREQTLNQMLVEMDGFDGNEGIILIAATNRPDVLDPALLRPGRFDRQVIVALPDIRGRE 313
Query: 318 EILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKA 376
+ILKVH R++ L K+VD +IA T G SGADL + EA +FA R + V+ +F +A
Sbjct: 314 QILKVHMRKVPLSKDVDPMIIARGTPGFSGADLANLVNEAALFAARLDKRVVSMLEFERA 373
Query: 377 VDK-VLGNERK 386
DK ++G+ER+
Sbjct: 374 KDKMMMGSERR 384
>sp|Q55700|FTH1_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|7446577|pir||S76378 cell
division protein ftsH-1 - Synechocystis sp. (strain PCC
6803) >gi|1001602|dbj|BAA10230.1| (D64000) cell division
protein FtsH [Synechocystis sp.]
Length = 627
Score = 230 bits (580), Expect = 2e-59
Identities = 127/276 (46%), Positives = 169/276 (61%), Gaps = 9/276 (3%)
Query: 129 FEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKT 188
F++ + V ++D+ G+ + +EL+E + LK PE F VG PKGVLL GPPG GKT
Sbjct: 161 FQMDAKTGVMFDDVAGIDEAKEELQEVVTF-LKQPERFTAVGAKIPKGVLLVGPPGTGKT 219
Query: 189 LMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAK 248
L+AKA+A E F + GSE V ++G GA V +LF+ AKE AP +IFIDEIDA+G +
Sbjct: 220 LLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENAPCLIFIDEIDAVGRQ 279
Query: 249 RMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEV 308
R GG E +TL QLL EMDGF+ + +IAATNRPD+LD AL+RPGRFDR + V
Sbjct: 280 RGAGIGGGNDEREQTLNQLLTEMDGFEGNTGIIIIAATNRPDVLDSALMRPGRFDRQVMV 339
Query: 309 PLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTY 367
PD+ GR EIL+VH R KL V + IA T G SGADL + EA + R R++
Sbjct: 340 DAPDYSGRKEILEVHARNKKLAPEVSIDSIARRTPGFSGADLANLLNEAAILTARRRKSA 399
Query: 368 VTQEDFLKAVDKVLGN-------ERKLLQQITSHEI 396
+T + AVD+V+ + K + I HE+
Sbjct: 400 ITLLEIDDAVDRVVAGMEGTPLVDSKSKRLIAYHEV 435
>pir||E81157 cell division protein FtsH NMB0798 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226031|gb|AAF41211.1| (AE002433) cell division
protein FtsH [Neisseria meningitidis MC58]
Length = 655
Score = 229 bits (579), Expect = 3e-59
Identities = 124/252 (49%), Positives = 166/252 (65%), Gaps = 3/252 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G + +E++E ++ LK P ++ +G P+G+LL G PG GKTL+AKA+A
Sbjct: 157 VTFADVAGCDEAKEEVQEIVDY-LKAPNRYQSLGGRVPRGILLAGSPGTGKTLLAKAIAG 215
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F + GS+ V ++G GA V ++FE AK+ AP IIFIDEIDA+G +R GG
Sbjct: 216 EAGVPFFSISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRQRGAGLGGG 275
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF+ V VIAATNRPD+LDPAL RPGRFDR + VPLPD GR
Sbjct: 276 NDEREQTLNQLLVEMDGFESNQTVIVIAATNRPDVLDPALQRPGRFDRQVVVPLPDIRGR 335
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
+IL VH++++ L ++VDL +A T G SGADL + EA +FA R + V Q DF
Sbjct: 336 EQILNVHSKKVPLDESVDLLSLARGTPGFSGADLANLVNEAALFAGRRNKVKVDQSDFED 395
Query: 376 AVDKV-LGNERK 386
A DK+ +G ER+
Sbjct: 396 AKDKIYMGPERR 407
>pir||F83053 cell division protein FtsH PA4751 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951013|gb|AAG08137.1|AE004888_12 (AE004888) cell
division protein FtsH [Pseudomonas aeruginosa]
Length = 639
Score = 229 bits (577), Expect = 5e-59
Identities = 125/258 (48%), Positives = 165/258 (63%), Gaps = 3/258 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
++ T+ D+ G + +E+ E +E L+ P F+ +G P+GVL+ GPPG GKTL+AK
Sbjct: 147 DQVKTTFADVAGCDEAKEEVSELVEF-LRDPGKFQRLGGRIPRGVLMVGPPGTGKTLLAK 205
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V ++F+ AK+ AP IIFIDEIDA+G R
Sbjct: 206 AIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFDQAKKHAPCIIFIDEIDAVGRHRGAG 265
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF+ + VIAATNRPD+LDPALLRPGRFDR + V LPD
Sbjct: 266 LGGGHDEREQTLNQLLVEMDGFEMNDGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPD 325
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR +ILKVH R++ L +VD VIA T G SGADL + EA +FA R + V
Sbjct: 326 IRGREQILKVHMRKVPLGDHVDPAVIARGTPGFSGADLANLVNEASLFAARSNKRIVDMR 385
Query: 372 DFLKAVDKV-LGNERKLL 388
+F A DK+ +G ERK +
Sbjct: 386 EFELAKDKIMMGAERKTM 403
>sp|P96942|FTSH_MYCTU CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7478074|pir||C70956 probable
ftsH protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2113966|emb|CAB08956.1| (Z95557) ftsH [Mycobacterium
tuberculosis]
Length = 760
Score = 228 bits (576), Expect = 7e-59
Identities = 122/264 (46%), Positives = 168/264 (63%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P T+ D+ G+ + ++EL E + L++P ++ +G PKGVLLYGPPG GKTL+A+
Sbjct: 156 DMPKTTFADVAGVDEAVEELYEIKDF-LQNPSRYQALGAKIPKGVLLYGPPGTGKTLLAR 214
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V +LFE AK+ +P IIF+DEIDA+G +R
Sbjct: 215 AVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAG 274
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF R V +IAATNRPDILDPALLRPGRFDR I V PD
Sbjct: 275 LGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPD 334
Query: 313 FEGRLEILKVHTR-RMKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR +L+VH++ + + DL +A+ T G +GADL + EA + RE T +T
Sbjct: 335 LAGRRAVLRVHSKGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGP 394
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
+AVD+V+G R+ + I+ E
Sbjct: 395 ALEEAVDRVIGGPRRKGRIISEQE 418
>sp|P94304|FTSH_BACFI CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1813473|gb|AAB41679.1|
(U61844) cell division protein [Bacillus firmus]
Length = 679
Score = 228 bits (575), Expect = 9e-59
Identities = 125/264 (47%), Positives = 163/264 (61%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
++ + D+ G ++ QEL E +E LK P F +G PKGVLL GPPG GKTL+A+
Sbjct: 159 DKKKAKFKDVAGADEEKQELVEVVEF-LKDPRKFSAIGARIPKGVLLVGPPGTGKTLLAR 217
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V +LFE AK+ AP IIFIDEIDA+G +R
Sbjct: 218 AVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAG 277
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF + +IAATNR DILDPALLRPGRFDR I+V PD
Sbjct: 278 LGGGHDEREQTLNQLLVEMDGFSANEGIIIIAATNRADILDPALLRPGRFDRQIQVNRPD 337
Query: 313 FEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR E+LKVH R L +V+L+ IA T G SGADL+ + EA + A R T ++
Sbjct: 338 VNGREEVLKVHARNKPLNDDVNLKTIATRTPGFSGADLENLLNEAALVAARHDHTKISMI 397
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
+A+D+V+ K + I+ E
Sbjct: 398 HIEEAIDRVIAGPAKKSRVISPKE 421
>gb|AAB66377.1| (U97567) FtsH [Helicobacter pylori]
Length = 632
Score = 228 bits (575), Expect = 9e-59
Identities = 127/266 (47%), Positives = 174/266 (64%), Gaps = 4/266 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+PNV +ND+ G ++ +E+ E ++ LK+PE + +G PKGVLL GPPG GKTL+AK
Sbjct: 163 EKPNVRFNDMAGNEEAKEEVVEIVDF-LKYPERYANLGAKIPKGVLLVGPPGTGKTLLAK 221
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR-MD 251
A+A E + F + GS + ++G GA V +LFE AK++AP+IIFIDEIDAIG R
Sbjct: 222 AVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDLFETAKKQAPSIIFIDEIDAIGKSRAAG 281
Query: 252 ETTGGEREVNRTLMQLLAEMDGF-DPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
G E +TL Q LAEMDGF V V+AATNRP+ILDPAL+RPGRFDR + V
Sbjct: 282 GVVSGNDEREQTLNQFLAEMDGFGSENAPVIVLAATNRPEILDPALMRPGRFDRQVLVDK 341
Query: 311 PDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
PDF GR+EILKVH + +KL N V+L+ +A++T G +GADL I EA + A R + V
Sbjct: 342 PDFNGRVEILKVHIKGVKLANDVNLQEVAKLTAGLAGADLANIINEAALLAGRNNQKEVK 401
Query: 370 QEDFLKAVDKVLGNERKLLQQITSHE 395
+ +AV++ + K ++I+ E
Sbjct: 402 LQHLKEAVERGIAGLEKKSRRISPKE 427
>sp|P37476|FTSH_BACSU CELL DIVISION PROTEIN FTSH HOMOLOG >gi|2126904|pir||S66099 cell
division protein FtsH - Bacillus subtilis
>gi|7446572|pir||E69627 cell-division protein / general
stress protein ftsH - Bacillus subtilis
>gi|467458|dbj|BAA05304.1| (D26185) cell division
protein [Bacillus subtilis] >gi|2632336|emb|CAB11845.1|
(Z99104) cell-division protein and general stress
protein (class III heat-shock) [Bacillus subtilis]
Length = 637
Score = 228 bits (574), Expect = 1e-58
Identities = 127/264 (48%), Positives = 162/264 (61%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+ V + D+ G ++ QEL E +E LK P F E+G PKGVLL GPPG GKTL+AK
Sbjct: 154 EKKRVKFKDVAGADEEKQELVEVVEF-LKDPRKFAELGARIPKGVLLVGPPGTGKTLLAK 212
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A A E F + GS+ V ++G GA V +LFE AK+ AP +IFIDEIDA+G +R
Sbjct: 213 ACAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCLIFIDEIDAVGRQRGAG 272
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF + +IAATNR DILDPALLRPGRFDR I V PD
Sbjct: 273 LGGGHDEREQTLNQLLVEMDGFSANEGIIIIAATNRADILDPALLRPGRFDRQITVDRPD 332
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR +LKVH R L + V+L+ IA T G SGADL+ + EA + A R+ + +
Sbjct: 333 VIGREAVLKVHARNKPLDETVNLKSIAMRTPGFSGADLENLLNEAALVAARQNKKKIDAR 392
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
D +A D+V+ K + I+ E
Sbjct: 393 DIDEATDRVIAGPAKKSRVISKKE 416
>sp|P71377|FTH1_HAEIN CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|1574793|gb|AAC22979.1|
(U32812) cell division protein (ftsH) [Haemophilus
influenzae Rd]
Length = 635
Score = 228 bits (574), Expect = 1e-58
Identities = 121/254 (47%), Positives = 166/254 (64%), Gaps = 3/254 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G + +E+ E ++ L+ P F+ +G PKG+L+ GPPG GKTL+A+A+A
Sbjct: 148 VTFADVAGCDEAKEEVGEIVDF-LRDPNKFQNLGGKIPKGILMVGPPGTGKTLLARAIAG 206
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F + GS+ V ++G GA V ++FE AK+ AP +IFIDEIDA+G +R GG
Sbjct: 207 EAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKNAPCLIFIDEIDAVGRQRGAGLGGG 266
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL Q+L EMDGF V VIAATNRPD+LDPAL RPGRFDR + V LPD +GR
Sbjct: 267 HDEREQTLNQMLVEMDGFSGNDGVIVIAATNRPDVLDPALTRPGRFDRQVVVGLPDVKGR 326
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
+ILKVH R++ + ++VD +A T G SGADL + EA +FA R + VT +F K
Sbjct: 327 EQILKVHMRKVSVAQDVDAMTLARGTPGYSGADLANLVNEAALFAARVNKRTVTMLEFEK 386
Query: 376 AVDKV-LGNERKLL 388
A DK+ +G ER+ +
Sbjct: 387 AKDKINMGPERRTM 400
>sp|P72991|FTH4_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 4 >gi|7446576|pir||S74970 cell
division protein ftsH-2 - Synechocystis sp. (strain PCC
6803) >gi|1652085|dbj|BAA17010.1| (D90902) cell division
protein FtsH [Synechocystis sp.]
Length = 616
Score = 227 bits (573), Expect = 2e-58
Identities = 121/251 (48%), Positives = 160/251 (63%), Gaps = 2/251 (0%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT+ D+ G+++ EL E ++ LK+ + F E+G PKGVLL GPPG GKTL+AKA+A
Sbjct: 158 VTFGDVAGIEQAKLELTEVVDF-LKNADRFTELGAKIPKGVLLVGPPGTGKTLLAKAVAG 216
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F + GSE V ++G GA V +LFE AK AP I+FIDEIDA+G +R GG
Sbjct: 217 EAGVPFFSISGSEFVEMFVGVGASRVRDLFEQAKANAPCIVFIDEIDAVGRQRGAGLGGG 276
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF+ + ++AATNRPD+LD AL+RPGRFDR + V PD+ GR
Sbjct: 277 NDEREQTLNQLLTEMDGFEGNTGIIIVAATNRPDVLDSALMRPGRFDRQVVVDRPDYAGR 336
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
EIL VH R L ++VDL IA T G +GADL + EA + A R T ++ ++
Sbjct: 337 REILNVHARGKTLSQDVDLDKIARRTPGFTGADLSNLLNEAAILAARRNLTEISMDEVND 396
Query: 376 AVDKVLGNERK 386
A+D+VL K
Sbjct: 397 AIDRVLAGPEK 407
>gi|5802970 AFG3-like 2; ATPase family gene 3-like 2; ATPase family gene 3,
yeast [Homo sapiens] >gi|5457357|emb|CAB48398.1|
(Y18314) paraplegin-like protein [Homo sapiens]
Length = 797
Score = 227 bits (573), Expect = 2e-58
Identities = 121/265 (45%), Positives = 165/265 (61%), Gaps = 6/265 (2%)
Query: 136 NVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALA 195
+V + D+ G ++ E+ E + LK+P+ ++++G PKG +L GPPG GKTL+AKA A
Sbjct: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
Query: 196 HEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTG 255
E N FI V GSE + ++G G V +LF LA++ AP I+FIDEIDA+G KR G
Sbjct: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
G+ E TL QLL EMDGF+ NV ++A TNRPDILDPALLRPGRFDR I + PD +G
Sbjct: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
Query: 316 RLEILKVHTRRMKL-----KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
R I KVH R +KL K+ R +A +T G SGAD+ + EA + A R + Q
Sbjct: 483 RASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQ 542
Query: 371 EDFLKAVDKVLGNERKLLQQITSHE 395
+ F +A+++V+G K Q + E
Sbjct: 543 KHFEQAIERVIGGLEKKTQVLQPEE 567
>sp|P73437|FTH3_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 3 >gi|7446571|pir||S77374 cell
division protein ftsH-4 - Synechocystis sp. (strain PCC
6803) >gi|1652556|dbj|BAA17477.1| (D90906) cell division
protein FtsH [Synechocystis sp.]
Length = 628
Score = 227 bits (572), Expect = 2e-58
Identities = 124/262 (47%), Positives = 171/262 (64%), Gaps = 4/262 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
VT++D+ G+++ EL E ++ LK P+ + +G PKGVLL GPPG GKTL+AKA A
Sbjct: 171 VTFDDVAGVEEAKTELSEVVDF-LKFPQRYTALGAKIPKGVLLVGPPGTGKTLLAKAAAG 229
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET-TG 255
E F + GSE V ++G GA V +LFE AK++AP I+FIDE+DAIG R G
Sbjct: 230 EAGVPFFIISGSEFVELFVGAGAARVRDLFEQAKKQAPCIVFIDELDAIGKSRASGAFMG 289
Query: 256 GEREVNRTLMQLLAEMDGFDPRG-NVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
G E +TL QLL EMDGF G V V+AATNRP+ LDPALLRPGRFDR + V PD
Sbjct: 290 GNDEREQTLNQLLTEMDGFSAAGATVIVLAATNRPETLDPALLRPGRFDRQVLVDRPDLA 349
Query: 315 GRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDF 373
GRL+IL+++ +++KL K V+L+ IA T G +GADL + EA + A R ++ VT+ DF
Sbjct: 350 GRLKILEIYAKKIKLDKEVELKNIATRTPGFAGADLANLVNEAALLAARNKQDSVTEADF 409
Query: 374 LKAVDKVLGNERKLLQQITSHE 395
+A+++V+ K + ++ E
Sbjct: 410 REAIERVVAGLEKKSRVLSDKE 431
>sp|O83746|FTSH_TREPA CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446583|pir||H71285 probable
cell division protein (ftsH) - syphilis spirochete
>gi|3323067|gb|AAC65728.1| (AE001247) cell division
protein (ftsH) [Treponema pallidum]
Length = 609
Score = 227 bits (572), Expect = 2e-58
Identities = 123/267 (46%), Positives = 173/267 (64%), Gaps = 5/267 (1%)
Query: 132 IERPNVT--YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTL 189
+E VT + D+ G+ + +EL E ++ LK P+ + E+G P+GVLL GPPG GKTL
Sbjct: 131 VEEGKVTTRFADVAGVDEAKEELMEVVDF-LKFPKKYTEIGGKIPRGVLLVGPPGTGKTL 189
Query: 190 MAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR 249
+A+A+A E + F R+ GS+ + ++G GA V +LF+ A+EKAP IIFIDE+DAIG R
Sbjct: 190 LARAVAGEASVPFFRISGSDFIEMFVGIGASRVRDLFKQAREKAPGIIFIDELDAIGKSR 249
Query: 250 MDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVP 309
++ + E +TL QLL EMDGFD + ++AATNRPD+LDPALLRPGRFDR + V
Sbjct: 250 LNAIHSND-EREQTLNQLLVEMDGFDNTTGLILLAATNRPDVLDPALLRPGRFDRQVCVD 308
Query: 310 LPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYV 368
PD +GR IL++H + +KL VDL+ +A IT G SGADL + EA + A+R R V
Sbjct: 309 RPDLKGREAILRIHAQNVKLAPEVDLKAVARITGGYSGADLANVVNEAALLAVRSGRAQV 368
Query: 369 TQEDFLKAVDKVLGNERKLLQQITSHE 395
+ D +AV+K + +K + I E
Sbjct: 369 IETDLDEAVEKTMIGLQKKSRVIREEE 395
>pir||D75502 cell division protein FtsH - Deinococcus radiodurans (strain R1)
>gi|6458277|gb|AAF10160.1|AE001916_6 (AE001916) cell
division protein FtsH [Deinococcus radiodurans]
Length = 618
Score = 227 bits (572), Expect = 2e-58
Identities = 122/252 (48%), Positives = 166/252 (65%), Gaps = 3/252 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+T+ D+ G + Q+L+E +E L+ PE + ++G P+GVLL GPPG GKTL+AKA+A
Sbjct: 151 LTFADVAGCDEAKQDLQEVVEF-LRQPEKYHQLGARIPRGVLLVGPPGSGKTLLAKAVAG 209
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E + + GS+ V ++G GA V +LFE A++ +P I+FIDEIDA+G KR GG
Sbjct: 210 EAKVPYFSISGSDFVEMFVGVGAARVRDLFEQARKASPCIVFIDEIDAVGRKRGMNIQGG 269
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF +V ++AATNRPD+LD ALLRPGRFDR + V PD GR
Sbjct: 270 NDEREQTLNQLLVEMDGFGSGQDVIILAATNRPDVLDAALLRPGRFDRQVVVDAPDVRGR 329
Query: 317 LEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
+IL++H+R+ L +VDL VIA T G GADL+ + EA + A RE R +T D +
Sbjct: 330 EQILRIHSRKKPLDVSVDLGVIARRTAGMVGADLENLLNEAALLAAREGRNRITGRDVDE 389
Query: 376 AVDKVL-GNERK 386
A D+VL G ER+
Sbjct: 390 ARDRVLMGPERR 401
>sp|P73179|FTH2_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 2 >gi|7446575|pir||S75291 cell
division protein ftsH-3 - Synechocystis sp. (strain PCC
6803) >gi|1652282|dbj|BAA17205.1| (D90904) cell division
protein FtsH [Synechocystis sp.]
Length = 665
Score = 226 bits (570), Expect = 4e-58
Identities = 123/276 (44%), Positives = 168/276 (60%), Gaps = 9/276 (3%)
Query: 129 FEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKT 188
F++ + V ++D+ G+ + +EL+E + LK PE F +G P+GVLL GPPG GKT
Sbjct: 200 FQMEAKTGVGFDDVAGIDEAKEELQEVVTF-LKQPEKFTAIGAKIPRGVLLIGPPGTGKT 258
Query: 189 LMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAK 248
L+AKA+A E F + GSE V ++G GA V +LF+ AKE AP ++FIDEIDA+G +
Sbjct: 259 LLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENAPCLVFIDEIDAVGRQ 318
Query: 249 RMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEV 308
R GG E +TL QLL EMDGF+ + VIAATNRPD+LD ALLRPGRFDR + V
Sbjct: 319 RGVGYGGGNDEREQTLNQLLTEMDGFEGNSGIIVIAATNRPDVLDLALLRPGRFDRQVTV 378
Query: 309 PLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTY 367
PD +GR IL +H + KL + V L IA T G +GADL + EA +F R R+
Sbjct: 379 DYPDVQGRELILAIHAQNKKLHEEVQLAAIARRTPGFTGADLANVLNEAAIFTARRRKEA 438
Query: 368 VTQEDFLKAVDKVLGN-------ERKLLQQITSHEI 396
+T + A+D+V+ + K + I HE+
Sbjct: 439 ITMAEVNDAIDRVVAGMEGTPLVDSKSKRLIAYHEV 474
>gi|11431428 similar to proteasome (prosome, macropain) 26S subunit, ATPase, 1
(H. sapiens) [Homo sapiens]
Length = 294
Score = 226 bits (570), Expect = 4e-58
Identities = 118/237 (49%), Positives = 162/237 (67%), Gaps = 8/237 (3%)
Query: 13 ENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLD 72
E DY+ + IR E Q++ LE E+ E E RS++ LR P GT+ E++D
Sbjct: 66 ERIKDYLLMEEEFIRNQE-QMKPLE---EKQEEE----RSKVDDLRGTPMSVGTLEEIID 117
Query: 73 DDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVI 132
D+ AIV G V I ++++D L PG V L+ + A+I +L DP V +V
Sbjct: 118 DNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVE 177
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P TY DIGGL Q+QE++E++ELPL HPE +EE+GI PPKGV+LYGPPG GKTL+AK
Sbjct: 178 KAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR 249
A+A++ +ATF+RVVGSEL++KY+G+G +LV ELF +A+E AP+I+FIDEIDAIG KR
Sbjct: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
>pir||T23322 hypothetical protein K04G2.3 - Caenorhabditis elegans
>gi|3878262|emb|CAB00040.1| (Z75712) contains similarity
to Pfam domain: PF00004 (ATPases associated with various
cellular activities (AAA)), Score=305.8,
E-value=1.6e-88, N=1~cDNA EST yk353e8.5 comes from this
gene [Caenorhabditis elegans]
Length = 724
Score = 226 bits (569), Expect = 5e-58
Identities = 124/272 (45%), Positives = 170/272 (61%), Gaps = 6/272 (2%)
Query: 124 PTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPP 183
PT + ++E PNV++NDIGG ++ E+++A+ P KHPE FE GIDPP G+LLYGPP
Sbjct: 443 PTGIRQFILEVPNVSWNDIGGNEELKLEIQQAVIWPQKHPEAFERFGIDPPAGILLYGPP 502
Query: 184 GCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEID 243
GC KTL+A+ALA E F+ V G EL K++G+ + + +LF A++ APTI+F DEID
Sbjct: 503 GCSKTLIARALASEAKMNFLAVKGPELFSKWVGDSEKAIRDLFSRARQVAPTIVFFDEID 562
Query: 244 AIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFD 303
A+G+ R E + G + R L QLL E+DG + V ++AATNRPD LD ALLRPGR D
Sbjct: 563 AVGSSRGSEKSSGVSD--RVLAQLLTELDGLEKSSRVILLAATNRPDQLDSALLRPGRLD 620
Query: 304 RLIEVPLPDFEGRLEILKVHTRRMKLKNV--DLRVIAEITEGASGADLKAIATEAGMFAI 361
R I V LP R IL++ T++MK + + + E T G SGA+L A+ A MFA+
Sbjct: 621 RAIYVGLPCEVTRRAILEMRTKKMKFDDTVRTIDKLVEKTSGYSGAELVAVCRTAAMFAM 680
Query: 362 RER--RTYVTQEDFLKAVDKVLGNERKLLQQI 391
RE T V F +A+ V+ L +I
Sbjct: 681 RESIDATIVQWTHFEQALAAVVSRTEAYLLEI 712
>pir||E82299 cell division protein FtsH VC0637 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655072|gb|AAF93803.1|
(AE004149) cell division protein FtsH [Vibrio cholerae]
Length = 651
Score = 225 bits (568), Expect = 6e-58
Identities = 123/261 (47%), Positives = 170/261 (65%), Gaps = 5/261 (1%)
Query: 138 TYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHE 197
T++D+ G + ++++E ++ L+ P F+++G P GVL+ GPPG GKTL+AKA+A E
Sbjct: 154 TFSDVAGCDEAKEDVKELVDY-LRDPSRFQKLGGKIPTGVLMVGPPGTGKTLLAKAIAGE 212
Query: 198 VNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGE 257
F + GS+ V ++G GA V ++FE AK+ +P IIFIDEIDA+G +R GG
Sbjct: 213 AKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKASPCIIFIDEIDAVGRQRGAGVGGGH 272
Query: 258 REVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRL 317
E +TL Q+L EMDGF+ + VIAATNRPD+LDPALLRPGRFDR + V LPD GR
Sbjct: 273 DEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGRE 332
Query: 318 EILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKA 376
+ILKVH R++ L N V+ +IA T G SGADL + EA +FA R + V+ +F A
Sbjct: 333 QILKVHMRKVPLANDVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRNVSMVEFELA 392
Query: 377 VDKV-LGNERKLLQQITSHEI 396
DK+ +G ER+ + S EI
Sbjct: 393 KDKIMMGAERR--SMVMSEEI 411
>dbj|BAA88165.1| (AB024399) FtsH (FtsHcp) [Cyanidioschyzon merolae]
Length = 603
Score = 225 bits (567), Expect = 8e-58
Identities = 122/275 (44%), Positives = 170/275 (61%), Gaps = 9/275 (3%)
Query: 129 FEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKT 188
F+++ + + ++D+ G+++ +EL E + LK+P F VG PKGVLL GPPG GKT
Sbjct: 143 FQMVAKTGIMFDDVAGIEEAKEELAEVVAF-LKNPSKFLAVGASIPKGVLLVGPPGTGKT 201
Query: 189 LMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAK 248
L+AKA+A E + F + GSE V ++G GA V +LF+ AK+ AP ++FIDEIDA+G +
Sbjct: 202 LLAKAIAGEASVPFFSISGSEFVEMFVGVGASRVRDLFKKAKQNAPCLVFIDEIDAVGRQ 261
Query: 249 RMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEV 308
R GG E +TL QLL EMDGF+ V VIAATNR D+LD ALLRPGRFDR I V
Sbjct: 262 RGAGIGGGNDEREQTLNQLLTEMDGFEGNTGVIVIAATNRVDVLDAALLRPGRFDRQIMV 321
Query: 309 PLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTY 367
+PD + R+ ILKVH + KL V L +A T G +GADL + EA + A+R
Sbjct: 322 SMPDVKSRIAILKVHANQKKLHPQVSLEAVARRTAGFAGADLANLLNEAAILAVRRGLKQ 381
Query: 368 VTQEDFLKAVDKVLGN-------ERKLLQQITSHE 395
+T ++ A+D+V+ + K+ + I HE
Sbjct: 382 ITWKEIDDAIDRVIAGMEGTPIMDGKIKRLIAYHE 416
>pir||T11652 probable transitional endoplasmic reticulum ATPase - fission yeast
(Schizosaccharomyces pombe) (fragment)
>gi|2330848|emb|CAB11085.1| (Z98533) transitional
endoplasmic reticulum atpase [Schizosaccharomyces pombe]
Length = 432
Score = 224 bits (565), Expect = 1e-57
Identities = 127/296 (42%), Positives = 180/296 (59%), Gaps = 17/296 (5%)
Query: 111 TMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVG 170
TM S +P+ L V+E PNV + DIGGL++ +ELRE +++P+ + E F G
Sbjct: 85 TMDNFRFALGSSNPSALRETVVEVPNVRWEDIGGLEEVKRELRETVQMPVMYAEKFLRFG 144
Query: 171 IDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAK 230
+ P KGVL +GPPG GKTL+AKA+A+E +A FI V G EL+ + GE V ++F+ A+
Sbjct: 145 VTPSKGVLFFGPPGTGKTLLAKAIANECSANFISVKGPELLSMWFGESESNVRDIFDKAR 204
Query: 231 EKAPTIIFIDEIDAIGAKR---MDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATN 287
AP ++F+DE+D+I R ++ GG+R VN QLL EMDG + + NV VI ATN
Sbjct: 205 AAAPCVVFLDELDSIAKARGASAGDSGGGDRVVN----QLLTEMDGVNSKKNVFVIGATN 260
Query: 288 RPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASG 346
RPD +DPAL+RPGR D+LI VPLPD E R IL+ R + ++VDLR +A+ T G SG
Sbjct: 261 RPDQIDPALMRPGRLDQLIYVPLPDEEARFSILQTQLRHTPVAEDVDLRAVAKATHGFSG 320
Query: 347 ADLKAIATEAGMFAIRE------RRTYVTQEDFLKAVDKVLGNERKLLQQITSHEI 396
ADL+ + A AI++ +R T E D V+ +E + Q+ H +
Sbjct: 321 ADLEFVVQRAVKLAIKDSIEEDIKRENETGE---APADDVVMDEDASVSQVQRHHV 373
>emb|CAA18796.1| (AL023093) cell division protein FtsH [Mycobacterium leprae]
Length = 787
Score = 224 bits (565), Expect = 1e-57
Identities = 120/264 (45%), Positives = 167/264 (62%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
+ P T+ D+ G+ + ++EL E + L++P ++ +G PKGVLLYGPPG GKTL+A+
Sbjct: 156 DMPKTTFADVAGVDEAVEELYEIKDF-LQNPCRYQTLGAKIPKGVLLYGPPGTGKTLLAR 214
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V +LF+ AK+ +P IIF+DEIDA+G +R
Sbjct: 215 AVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFDQAKQNSPCIIFVDEIDAVGRQRGTG 274
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF R V +IAATNRPDILDPALLRPGRFDR I V PD
Sbjct: 275 LGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPD 334
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR +L+VH++ + + DL +A+ T G +GADL + EA + RE +T
Sbjct: 335 LAGRRAVLRVHSKGKPIADDADLDGLAKRTVGMTGADLANVVNEAALLTARENGLVITGP 394
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
+AVD+V+G R+ + I+ E
Sbjct: 395 ALEEAVDRVIGGPRRKGRIISEQE 418
>dbj|BAB03804.1| (AP001507) cell-division protein (ATP-dependent Zn
metallopeptidase) [Bacillus halodurans]
Length = 657
Score = 224 bits (564), Expect = 2e-57
Identities = 123/264 (46%), Positives = 162/264 (60%), Gaps = 2/264 (0%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
++ + D+ G ++ QEL E +E LK P F +G PKGVLL GPPG GKTL+A+
Sbjct: 152 DKKKAKFKDVAGADEEKQELVEVVEF-LKDPRKFSAIGARIPKGVLLVGPPGTGKTLLAR 210
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE 252
A+A E F + GS+ V ++G GA V +LFE AK+ AP IIFIDEIDA+G +R
Sbjct: 211 AVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAG 270
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
GG E +TL QLL EMDGF + +IAATNR DILDPALLRPGRFDR I V PD
Sbjct: 271 LGGGHDEREQTLNQLLVEMDGFSANEGIIIIAATNRADILDPALLRPGRFDRQITVGRPD 330
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+GR E+LKVH L +V+L+ IA T G SGADL+ + EA + A R+ ++
Sbjct: 331 VKGREEVLKVHASNKPLADDVNLKTIATRTPGFSGADLENLLNEAALVAARQDEKKISMV 390
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
+A+D+V+ K + I+ E
Sbjct: 391 HIEEAIDRVIAGPAKKSRVISEKE 414
>gb|AAC16243.2| (AF061748) cell division protein FtsH [Streptococcus pneumoniae]
Length = 652
Score = 223 bits (563), Expect = 2e-57
Identities = 122/260 (46%), Positives = 166/260 (62%), Gaps = 2/260 (0%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V ++D+ G +++ QEL E +E LK P+ F ++G P GVLL GPPG GKTL+AKA+A
Sbjct: 184 VRFSDVAGAEEEKQELVEVVEF-LKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAVAG 242
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F + GS+ V ++G GA V LFE AK+ AP IIFIDEIDA+G +R GG
Sbjct: 243 EAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGG 302
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF+ + VIAATNR D+LDPALLRPGRFDR + V PD +GR
Sbjct: 303 NDEREQTLNQLLIEMDGFEGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGR 362
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
ILKVH + L ++VDL+++A+ T G GADL+ + EA + A R ++ + D +
Sbjct: 363 EAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVLNEAALVAARRNKSIIDASDIDE 422
Query: 376 AVDKVLGNERKLLQQITSHE 395
A D+V+ K + ++ E
Sbjct: 423 AEDRVIAGPSKKDKTVSQKE 442
>sp|O69076|FTSH_STRPN CELL DIVISION PROTEIN FTSH HOMOLOG
Length = 498
Score = 223 bits (563), Expect = 2e-57
Identities = 122/260 (46%), Positives = 166/260 (62%), Gaps = 2/260 (0%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V ++D+ G +++ QEL E +E LK P+ F ++G P GVLL GPPG GKTL+AKA+A
Sbjct: 39 VRFSDVAGAEEEKQELVEVVEF-LKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAVAG 97
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F + GS+ V ++G GA V LFE AK+ AP IIFIDEIDA+G +R GG
Sbjct: 98 EAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGG 157
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E +TL QLL EMDGF+ + VIAATNR D+LDPALLRPGRFDR + V PD +GR
Sbjct: 158 NDEREQTLNQLLIEMDGFEGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGR 217
Query: 317 LEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
ILKVH + L ++VDL+++A+ T G GADL+ + EA + A R ++ + D +
Sbjct: 218 EAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVLNEAALVAARRNKSIIDASDIDE 277
Query: 376 AVDKVLGNERKLLQQITSHE 395
A D+V+ K + ++ E
Sbjct: 278 AEDRVIAGPSKKDKTVSQKE 297
>gb|AAC44563.1| (U59452) HpFtsH [Helicobacter pylori]
Length = 632
Score = 223 bits (562), Expect = 3e-57
Identities = 126/266 (47%), Positives = 172/266 (64%), Gaps = 4/266 (1%)
Query: 133 ERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAK 192
E+PNV +ND+ G ++ +E+ E ++ LK+PE + +G PKGVLL GPPG GKTL+AK
Sbjct: 163 EKPNVRFNDMAGNEEAKEEVVEIVDF-LKYPERYANLGAKIPKGVLLVGPPGTGKTLLAK 221
Query: 193 ALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR-MD 251
A+A E + F + GS + ++G GA V +LFE AK++AP+IIFIDEIDAI R
Sbjct: 222 AVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDLFETAKKQAPSIIFIDEIDAIPKSRAAG 281
Query: 252 ETTGGEREVNRTLMQLLAEMDGF-DPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
G E +TL QLLAEMDGF V V+AATNRP+ILDPAL+RPGRFDR + V
Sbjct: 282 GMISGNDEREQTLNQLLAEMDGFGSENAPVIVLAATNRPEILDPALMRPGRFDRQVLVDK 341
Query: 311 PDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVT 369
PDF GR+EILKV + +KL N V+ +A++T G +GADL I EA + A R + V
Sbjct: 342 PDFNGRVEILKVDIKGVKLANDVNFEEVAKLTAGLAGADLANIINEAALLAGRNNQKEVK 401
Query: 370 QEDFLKAVDKVLGNERKLLQQITSHE 395
Q+ +AV++ + K ++I+ E
Sbjct: 402 QQHLKEAVERGIAGLEKKSRRISPKE 427
>pir||G75582 cell division protein FtsH - Deinococcus radiodurans (strain R1)
>gi|6460771|gb|AAF12476.1|AE001863_101 (AE001863) cell
division protein FtsH [Deinococcus radiodurans]
Length = 655
Score = 222 bits (561), Expect = 4e-57
Identities = 123/252 (48%), Positives = 164/252 (64%), Gaps = 3/252 (1%)
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
+ D+ G ++ +EL E ++ LK+P + ++G + PKGVLL GPPG GKTL+A+A+A E
Sbjct: 199 FTDVAGHEEAKRELIEVVDF-LKNPAKYHQIGAEIPKGVLLVGPPGTGKTLLARAVAGEA 257
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
+ F V SE + ++G GA V LFE A++ AP IIFIDEID+IG KR GG
Sbjct: 258 DVPFFSVSASEFMEMFVGVGASRVRTLFEDARKSAPAIIFIDEIDSIGRKRGAGIGGGHD 317
Query: 259 EVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
E +TL Q+L+EMDGFD +V V+ ATNRPD+LDPALLRPGRFDR + + LP+ + R
Sbjct: 318 EREQTLNQILSEMDGFDKSSSVIVLGATNRPDVLDPALLRPGRFDRQVTIDLPNLKEREA 377
Query: 319 ILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAV 377
ILKVH R L + VD+ IA+ T SGADLK I EA + A R +T + DF +A+
Sbjct: 378 ILKVHLRNKPLGEGVDVPEIAKSTPYFSGADLKNITNEAALEAARVGKTKIDMSDFYRAL 437
Query: 378 DKV-LGNERKLL 388
DK+ LG E L
Sbjct: 438 DKITLGLENSSL 449
>sp|P46469|FTSH_LACLA CELL DIVISION PROTEIN FTSH HOMOLOG >gi|2126621|pir||S28533 tma
protein - Lactococcus lactis >gi|44027|emb|CAA48877.1|
(X69123) Tma protein [Lactococcus lactis]
Length = 695
Score = 217 bits (548), Expect = 1e-55
Identities = 122/265 (46%), Positives = 166/265 (62%), Gaps = 5/265 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V + D+ G +++ QEL E ++ LK+P+ + ++G P GVLL GPPG GKTL+AKA+A
Sbjct: 190 VRFADVAGSEEEKQELVEVVDF-LKNPKKYHDLGARIPAGVLLEGPPGTGKTLLAKAVAG 248
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F + GS+ V ++G GA V +LFE AK+ AP+IIFIDEIDA+G +R GG
Sbjct: 249 EAGVPFYSISGSDFVEMFVGVGASRVRDLFENAKKTAPSIIFIDEIDAVGRQRGAGLGGG 308
Query: 257 EREVNRTLMQLLAEMDGFDPRGN-VKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
E +TL QLL EMDGF GN V VIAATNR D+LDPALLRPGRFDR + V PD +G
Sbjct: 309 NDEREQTLNQLLVEMDGFQDDGNSVIVIAATNRSDVLDPALLRPGRFDRKVLVGAPDVKG 368
Query: 316 RLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFL 374
R +LKVH + L +VDL +A T G GADL+ + EA + A R+ + + D
Sbjct: 369 REAVLKVHAKNKPLASDVDLHNVATQTPGYVGADLENVLNEAALVAARQNKKEINAADID 428
Query: 375 KAVDKVLGNERK--LLQQITSHEII 397
+ +D+ + K +Q + EI+
Sbjct: 429 EGMDRAMAGPAKKDRIQSMREREIV 453
>pir||B81376 probable membrane bound ATPase (EC 3.4.24.-) Cj1005c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968440|emb|CAB73261.1| (AL139076) putative membrane
bound ATPase [Campylobacter jejuni]
Length = 538
Score = 214 bits (540), Expect = 1e-54
Identities = 117/253 (46%), Positives = 167/253 (65%), Gaps = 5/253 (1%)
Query: 136 NVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALA 195
N+T+ND+ G+ + EL E ++ L++P+ ++E G+ PKGVL+ GPPG GKTL+AKA+A
Sbjct: 148 NITFNDVAGVDEVKMELSELVDF-LQNPKKYKEFGVKMPKGVLMVGPPGVGKTLIAKAVA 206
Query: 196 HEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTG 255
E F GS V Y+G GA+ V ELF AK AP+I+FIDEIDA+G K E +
Sbjct: 207 GEAGVPFFYQSGSSFVEIYVGMGAKRVRELFSKAKMMAPSIVFIDEIDAVG-KARGEMSN 265
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
ER+ TL QLL +MDGF+ V VIAATN+ +++DPALLR GRFDR I + LPDF+
Sbjct: 266 VERD--STLNQLLTQMDGFEDNSGVIVIAATNKIELMDPALLRSGRFDRRIFLSLPDFKD 323
Query: 316 RLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLK 375
RL+IL+++ + K N++L IA+ + G SGA L+ + EA + A+R V + DF
Sbjct: 324 RLKILEIYMKD-KNNNINLNKIAKASVGFSGAGLETLVNEAAINALRRNSALVEESDFYA 382
Query: 376 AVDKVLGNERKLL 388
++KVL ++K+L
Sbjct: 383 VLNKVLLGKKKIL 395
>pir||T34772 cell division protein ftsH - Streptomyces coelicolor
>gi|3191980|emb|CAA19379.1| (AL023797) cell division
protein FtsH homolog [Streptomyces coelicolor A3(2)]
Length = 648
Score = 213 bits (537), Expect = 3e-54
Identities = 119/258 (46%), Positives = 164/258 (63%), Gaps = 4/258 (1%)
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
+P T+ D+ G+ + EL + ++ LK+P+ + +G P+GVLL GPPG GKTL+A+A
Sbjct: 197 KPRTTFADVAGIDEVEGELSDVVDF-LKNPDAYRRMGAKMPRGVLLTGPPGTGKTLLARA 255
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIG-AKRMDE 252
+A E F SE + +G GA V ELF A++ AP+IIFIDEID IG A+
Sbjct: 256 VAGEAGVPFFSASASEFIEMIVGVGASRVRELFAEARKVAPSIIFIDEIDTIGRARGGGS 315
Query: 253 TTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPD 312
TGG E +TL Q+L EMDGF V VIAATNR DILD AL RPGRFDR++ V PD
Sbjct: 316 GTGGHDEREQTLNQILTEMDGFSGSEGVIVIAATNRADILDAALTRPGRFDRVVSVSPPD 375
Query: 313 FEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR IL++HTR + L ++DL +A T G +GA+L +A EA + A++ ++ VTQ
Sbjct: 376 RGGREAILEIHTREIPLAPDIDLAQVARTTPGMTGAELANLANEAALLAVKRKQERVTQA 435
Query: 372 DFLKAVDKV-LGNERKLL 388
+ +A++KV LG ER L+
Sbjct: 436 NLSEALEKVQLGAERPLV 453
>sp|P47695|FTSH_MYCGE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1361466|pir||E64250 cell
division protein ftsH - Mycoplasma genitalium
>gi|3845051|gb|AAC72477.1| (U39727) cell division
protein (ftsH) [Mycoplasma genitalium]
Length = 702
Score = 213 bits (536), Expect = 4e-54
Identities = 117/265 (44%), Positives = 165/265 (62%), Gaps = 2/265 (0%)
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ + V + +I GL+++ EL E ++ LK+P + ++G P+GV+LYGPPG GKTL+A
Sbjct: 223 LAKSTVKFTNIAGLQEEKHELLEIVDY-LKNPLKYAQMGARSPRGVILYGPPGTGKTLLA 281
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
KA+A E F + GS +G GA+ V +LF AK+ AP IIFIDEID++G+KR
Sbjct: 282 KAVAGEAGVPFFQSTGSGFEDMLVGVGAKRVRDLFNKAKKAAPCIIFIDEIDSVGSKRGR 341
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
V +TL QLLAEMDGF R V V+AATNR D+LD ALLRPGRFDR I++ LP
Sbjct: 342 VELSSYSVVEQTLNQLLAEMDGFTSRTGVVVMAATNRLDVLDDALLRPGRFDRHIQINLP 401
Query: 312 DFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D + R ILKVH L + + L +A+ T G SGA L+ + EA + A+R+ RT +
Sbjct: 402 DIKEREGILKVHAENKNLSSKISLLDVAKRTPGFSGAQLENVINEATLLAVRDNRTTINI 461
Query: 371 EDFLKAVDKVLGNERKLLQQITSHE 395
D +A+D+V+ K + I+ +
Sbjct: 462 NDIDEAIDRVIAGPAKKSRVISDED 486
>pir||T02738 hypothetical protein T9I4.16 - Arabidopsis thaliana
>gi|3461848|gb|AAC33234.1| (AC005315) putative AAA-type
ATPase [Arabidopsis thaliana]
Length = 807
Score = 209 bits (527), Expect = 4e-53
Identities = 114/262 (43%), Positives = 158/262 (59%), Gaps = 4/262 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+ + D+ G + QE+ E + LK+P+ +E++G PKG LL GPPG GKTL+AKA A
Sbjct: 317 IYFKDVAGCDEAKQEIMEFVHF-LKNPKKYEDLGAKIPKGALLVGPPGTGKTLLAKATAG 375
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
E F+ + GS+ + ++G G V LF+ A++ AP+IIFIDEIDAIG R GG
Sbjct: 376 ESGVPFLSISGSDFMEMFVGVGPSRVRHLFQEARQAAPSIIFIDEIDAIGRARGRGGLGG 435
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
E TL QLL EMDGF V V+A TNRPDILD ALLRPGRFDR I + PD +GR
Sbjct: 436 NDERESTLNQLLVEMDGFGTTAGVVVLAGTNRPDILDKALLRPGRFDRQITIDKPDIKGR 495
Query: 317 LEILKVHTRRMKLKNVD---LRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDF 373
+I K++ +++KL + + +A +T G +GAD+ + EA + A R VT F
Sbjct: 496 DQIFKIYLKKIKLDHEPSYYSQRLAALTPGFAGADIANVCNEAALIAARHEGATVTMAHF 555
Query: 374 LKAVDKVLGNERKLLQQITSHE 395
A+D+V+G K + I+ E
Sbjct: 556 ESAIDRVIGGLEKKNRVISKLE 577
>pir||D82934 ATP-dependent zinc metallopeptidase, cell division protein UU105
[imported] - Ureaplasma urealyticum
>gi|6899060|gb|AAF30511.1|AE002110_9 (AE002110)
ATP-dependent zinc metallopeptidase - cell division
protein [Ureaplasma urealyticum]
Length = 721
Score = 209 bits (526), Expect = 5e-53
Identities = 114/265 (43%), Positives = 164/265 (61%), Gaps = 5/265 (1%)
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ + V ++D+ G+ + +EL E ++ LK P+ + G PKGV+LYGPPG GKTL+A
Sbjct: 231 LTKSGVRFSDVAGIAEVKEELIEIVDF-LKEPKKYVAAGARIPKGVMLYGPPGTGKTLIA 289
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
KA+A E N F + GS ++G GAR V ELFE A++ AP IIFIDEID++ KR +
Sbjct: 290 KAVAGEANVPFFQTTGSSFEDTFVGVGARRVRELFEKARKSAPAIIFIDEIDSVAKKRGN 349
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
T + ++T+ QLL+E+DGFD V V+AATNR D LD A+LRPGRFDR I V LP
Sbjct: 350 SLTAVQ---DQTINQLLSELDGFDTSSGVIVMAATNRLDTLDDAILRPGRFDRQISVNLP 406
Query: 312 DFEGRLEILKVHTRRMKLK-NVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D R +IL++H+R L V L IA T G SGA L+ + EA + ++R++ T +
Sbjct: 407 DILEREQILRIHSRNKNLSAKVSLEDIARRTAGFSGAQLENVLNEAALLSVRDKATSIHM 466
Query: 371 EDFLKAVDKVLGNERKLLQQITSHE 395
+A+D+V+ + + I+ E
Sbjct: 467 NHLDEAIDRVIAGPSRPNKVISERE 491
>dbj|BAB08420.1| (AB025622) cell division protein FtsH protease-like [Arabidopsis
thaliana]
Length = 806
Score = 207 bits (522), Expect = 2e-52
Identities = 126/272 (46%), Positives = 162/272 (59%), Gaps = 8/272 (2%)
Query: 120 SSKDPTVLGFEVIERPNV-TYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVL 178
SS P L E+ NV T+ D+ G QEL E +E LK+P F +G PKG+L
Sbjct: 341 SSYSPKELNKEITPEKNVKTFKDVKGCDDAKQELEEVVEY-LKNPSKFTRLGGKLPKGIL 399
Query: 179 LYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIF 238
L G PG GKTL+AKA+A E F GSE ++G GAR V LF+ AK+KAP IIF
Sbjct: 400 LTGAPGTGKTLLAKAIAGEAGVPFFYRAGSEFEEMFVGVGARRVRSLFQAAKKKAPCIIF 459
Query: 239 IDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLR 298
IDEIDA+G+ R E +TL QLL EMDGF+ + V+AATN PDILDPAL R
Sbjct: 460 IDEIDAVGSTRKQ----WEGHTKKTLHQLLVEMDGFEQNEGIIVMAATNLPDILDPALTR 515
Query: 299 PGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAG 357
PGRFDR I VP PD GR EIL+++ + + ++VD++ IA T G +GADL + A
Sbjct: 516 PGRFDRHIVVPSPDVRGREEILELYLQGKPMSEDVDVKAIARGTPGFNGADLANLVNIAA 575
Query: 358 MFAIRERRTYVTQEDFLKAVDK-VLGNERKLL 388
+ A E ++ E A D+ V+G ERK +
Sbjct: 576 IKAAVEGAEKLSSEQLEFAKDRIVMGTERKTM 607
>gb|AAF60660.1| (AC024791) contains similarity to Pfam families PF00004 (ATPases
associated with various cellular activities),
score=326.5, E=3e-94, N=1) and PF01434 (Peptidase family
M41, score=289.2, E=5.1e-83, N=1) [Caenorhabditis
elegans]
Length = 852
Score = 206 bits (518), Expect = 5e-52
Identities = 115/264 (43%), Positives = 161/264 (60%), Gaps = 6/264 (2%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V + D+ G ++ E+ E + LK+P+ ++++G PKG +L GPPG GKTL+AKA A
Sbjct: 290 VKFADVAGCEEAKIEIMEFVNF-LKNPQQYKDLGAKIPKGAILTGPPGTGKTLLAKATAG 348
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDE-TTG 255
E N FI V GSE + ++G G V ++F +A++ +P I+FIDEIDA+G KR + G
Sbjct: 349 EANVPFITVSGSEFLEMFVGVGPARVRDMFSMARKNSPCILFIDEIDAVGRKRGGKGGMG 408
Query: 256 GEREVNRTLMQLLAEMDGF-DPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
G E TL QLL EMDGF +V VIAATNR DILD ALLRPGRFDR I VP+PD +
Sbjct: 409 GHSEQENTLNQLLVEMDGFTTDESSVIVIAATNRVDILDSALLRPGRFDRQIYVPVPDIK 468
Query: 315 GRLEILKVHTRRMKL---KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
GR I +VH ++ K V R +A T G SGAD+ + EA + A R+ ++ +
Sbjct: 469 GRASIFRVHLGPLRTSLDKTVLSRKLAAHTPGFSGADISNVCNEAALIAARDANHEISNK 528
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
F +A+++V+ K Q + E
Sbjct: 529 HFEQAIERVVAGMEKKTQVLQKEE 552
>gi|7305635 YME1-like 1 (S. cerevisiae); ATP-dependent metalloprotease FtsH1
[Mus musculus] >gi|3600100|gb|AAC35558.1| (AF090430)
ATP-dependent metalloprotease FtsH1 [Mus musculus]
Length = 715
Score = 203 bits (511), Expect = 3e-51
Identities = 116/274 (42%), Positives = 169/274 (61%), Gaps = 12/274 (4%)
Query: 118 LPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGV 177
L S+ DP ++ NVT+ + G+++ QEL+E +E LK+P+ F +G PKG+
Sbjct: 266 LDSAVDP-------VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTVLGGKLPKGI 317
Query: 178 LLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTII 237
LL GPPG GKTL+A+A+A E + F GSE ++G GA + LF AK AP +I
Sbjct: 318 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVI 377
Query: 238 FIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALL 297
FIDE+D++G KR++ +T+ QLLAEMDGF P V +I ATN P+ LD AL+
Sbjct: 378 FIDELDSVGGKRIESPM--HPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 435
Query: 298 RPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEA 356
RPGRFD + VP PD +GR EILK + ++K K+VD +IA T G SGA+L+ + +A
Sbjct: 436 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQA 495
Query: 357 GMFAIRERRTYVTQEDFLKAVDKVL-GNERKLLQ 389
+ A + + VT ++ + DK+L G ER+ ++
Sbjct: 496 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVE 529
>gb|AAF79577.1|AC022464_35 (AC022464) F22G5.10 [Arabidopsis thaliana]
Length = 843
Score = 203 bits (510), Expect = 4e-51
Identities = 112/263 (42%), Positives = 161/263 (60%), Gaps = 5/263 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+ + D+ G ++ QE+ E + L++P+ +E++G PKG LL GPPG GKTL+AKA A
Sbjct: 332 IYFKDVAGCEEAKQEIMEFVHF-LQNPKKYEDLGAKIPKGALLVGPPGTGKTLLAKATAG 390
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIG-AKRMDETTG 255
E F+ + GS+ + ++G G V LF+ A++ AP+IIFIDEIDAIG A+ +G
Sbjct: 391 ESAVPFLSISGSDFMEMFVGVGPSRVRNLFQEARQCAPSIIFIDEIDAIGRARGRGGFSG 450
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
G E TL QLL EMDGF V V+A TNRPDILD ALLRPGRFDR I + PD +G
Sbjct: 451 GNDERESTLNQLLVEMDGFGTTAGVVVLAGTNRPDILDKALLRPGRFDRQITIDKPDIKG 510
Query: 316 RLEILKVHTRRMKLKNVD---LRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
R +I +++ +++KL + + +A +T G +GAD+ + EA + A R VT
Sbjct: 511 RDQIFQIYLKKIKLDHEPSYYSQRLAALTPGFAGADIANVCNEAALIAARHEGATVTMAH 570
Query: 373 FLKAVDKVLGNERKLLQQITSHE 395
F A+D+V+G K + I+ E
Sbjct: 571 FDSAIDRVIGGLEKKNRVISKLE 593
>emb|CAC05251.1| (AL391604) putative mitochondrial respiratory chain complexes
assembly protein [Schizosaccharomyces pombe]
Length = 773
Score = 203 bits (510), Expect = 4e-51
Identities = 111/263 (42%), Positives = 157/263 (59%), Gaps = 5/263 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+ + D+ G+ + +E+ E ++ LK+P+ +E +G P+G +L GPPG GKTL+AKA A
Sbjct: 293 IKFADVAGVDEAKEEIMEFVKF-LKNPKFYERLGAKIPRGAILSGPPGTGKTLLAKATAG 351
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIG-AKRMDETTG 255
E N F+ V GSE + ++G G V +LF A++ AP IIFIDEIDAIG A+ G
Sbjct: 352 EANVPFLSVSGSEFLEMFVGVGPSRVRDLFATARKNAPCIIFIDEIDAIGKARGRGGQFG 411
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
E TL QLL EMDGF ++ V A TNRPD+LDPALLRPGRFDR I + PD G
Sbjct: 412 SNDERESTLNQLLVEMDGFTSSEHIVVFAGTNRPDVLDPALLRPGRFDRQITIDRPDIGG 471
Query: 316 RLEILKVHTRRMK-LKNVDL--RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
R +I KVH + +K N+DL + +A +T G +GAD+ + E + A R V
Sbjct: 472 REQIFKVHLKHIKAADNIDLIAKRLAVLTSGFTGADIMNVCNEGALIAARSNSNEVQMVH 531
Query: 373 FLKAVDKVLGNERKLLQQITSHE 395
F +A+++V K + ++ E
Sbjct: 532 FEQAIERVTAGLEKKSRVLSPEE 554
>pir||T41073 26s protease regulatory subunit S10b - fission yeast
(Schizosaccharomyces pombe) (fragment)
>gi|3560170|emb|CAA20682.1| (AL031525) 26s protease
regulatory subunit S10b [Schizosaccharomyces pombe]
Length = 249
Score = 202 bits (509), Expect = 5e-51
Identities = 102/242 (42%), Positives = 154/242 (63%), Gaps = 1/242 (0%)
Query: 16 DDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDR 75
+ Y +YL + R+ + +++ L L ++ + ++ L+ G V++ LD +R
Sbjct: 9 EKYKSYLLQH-REWDSKLKDLRFGNRDLVKKYDKTEDDIKSLQSVGQIIGEVLKQLDSER 67
Query: 76 AIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERP 135
IV+ +GPR+VV +++ L G RV+LD T+ I+ +LP DP V + +
Sbjct: 68 FIVKASSGPRYVVGCRNNVDQSHLVQGVRVSLDMTTLTIMRILPREVDPLVYNMSIEDPG 127
Query: 136 NVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALA 195
++++ +GGL +Q++ELRE IELPLK+PELF VGI PPKGVLLYGPPG GKTL+A+A+A
Sbjct: 128 DISFAGVGGLNEQIRELREVIELPLKNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAVA 187
Query: 196 HEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTG 255
+ F++VV S +V KYIGE AR++ E+F AKE P +IF+DEIDAIG +R E T
Sbjct: 188 ASLGVNFLKVVSSAIVDKYIGESARIIREMFGYAKEHEPCVIFMDEIDAIGGRRFSEGTS 247
Query: 256 GE 257
+
Sbjct: 248 AD 249
>gi|6325281 Mitochondrial member of the CDC48/PAS1/SEC18 family of ATPases;
Yme1p [Saccharomyces cerevisiae]
>gi|418575|sp|P32795|YME1_YEAST YME1 PROTEIN
(TAT-BINDING HOMOLOG 11) (OSD1 PROTEIN)
>gi|2133216|pir||S46608 YTA11 protein - yeast
(Saccharomyces cerevisiae) >gi|295582|gb|AAA02883.1|
(L14616) putative ATPase [Saccharomyces cerevisiae]
>gi|809589|emb|CAA89278.1| (Z49274) Yme1p [Saccharomyces
cerevisiae] >gi|1314098|emb|CAA95020.1| (Z71255) Yme1p
[Saccharomyces cerevisiae]
Length = 747
Score = 202 bits (508), Expect = 7e-51
Identities = 113/259 (43%), Positives = 157/259 (59%), Gaps = 6/259 (2%)
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ + NV ++D+ G + EL E ++ LK P +E +G PKGVLL GPPG GKTL+A
Sbjct: 273 VAKTNVKFDDVCGCDEARAELEEIVDF-LKDPTKYESLGGKLPKGVLLTGPPGTGKTLLA 331
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A A E F + GSE Y+G GA+ + +LF A+ +AP IIFIDE+DAIG KR
Sbjct: 332 RATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRNP 391
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ + +TL QLL E+DGF + +I ATN P+ LD AL RPGRFD+++ V LP
Sbjct: 392 K---DQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLP 448
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D GR +ILK H +++ L NVD +IA T G SGA+L + +A ++A ++ V
Sbjct: 449 DVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDM 508
Query: 371 EDFLKAVDKVL-GNERKLL 388
F A DK+L G ERK +
Sbjct: 509 SHFEWAKDKILMGAERKTM 527
>emb|CAA56954.1| (X81067) probable mitochondrial protein; nearly identical to YME1
[Saccharomyces cerevisiae]
Length = 747
Score = 202 bits (508), Expect = 7e-51
Identities = 113/259 (43%), Positives = 157/259 (59%), Gaps = 6/259 (2%)
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ + NV ++D+ G + EL E ++ LK P +E +G PKGVLL GPPG GKTL+A
Sbjct: 273 VAKTNVKFDDVCGCDEARAELEEIVDF-LKDPTKYESLGGKLPKGVLLTGPPGTGKTLLA 331
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A A E F + GSE Y+G GA+ + +LF A+ +AP IIFIDE+DAIG KR
Sbjct: 332 RATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRNP 391
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ + +TL QLL E+DGF + +I ATN P+ LD AL RPGRFD+++ V LP
Sbjct: 392 K---DQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLP 448
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D GR +ILK H +++ L NVD +IA T G SGA+L + +A ++A ++ V
Sbjct: 449 DVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDM 508
Query: 371 EDFLKAVDKVL-GNERKLL 388
F A DK+L G ERK +
Sbjct: 509 SHFEWAKDKILMGAERKTM 527
>dbj|BAA03839.1| (D16332) OSD1 gene product [Saccharomyces cerevisiae]
Length = 747
Score = 202 bits (508), Expect = 7e-51
Identities = 113/259 (43%), Positives = 157/259 (59%), Gaps = 6/259 (2%)
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ + NV ++D+ G + EL E ++ LK P +E +G PKGVLL GPPG GKTL+A
Sbjct: 273 VAKTNVKFDDVCGCDEARAELEEIVDF-LKDPTKYESLGGKLPKGVLLTGPPGTGKTLLA 331
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+A A E F + GSE Y+G GA+ + +LF A+ +AP IIFIDE+DAIG KR
Sbjct: 332 RATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRNP 391
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
+ + +TL QLL E+DGF + +I ATN P+ LD AL RPGRFD+++ V LP
Sbjct: 392 K---DQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLP 448
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQ 370
D GR +ILK H +++ L NVD +IA T G SGA+L + +A ++A ++ V
Sbjct: 449 DVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDM 508
Query: 371 EDFLKAVDKVL-GNERKLL 388
F A DK+L G ERK +
Sbjct: 509 SHFEWAKDKILMGAERKTM 527
>gb|AAD20962.1| (AF070656) FtsH homolog [Homo sapiens]
Length = 517
Score = 201 bits (506), Expect = 1e-50
Identities = 115/274 (41%), Positives = 169/274 (60%), Gaps = 12/274 (4%)
Query: 118 LPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGV 177
L S+ DP ++ NVT+ + G+++ QEL+E +E LK+P+ F +G PKG+
Sbjct: 70 LDSAVDP-------VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGI 121
Query: 178 LLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTII 237
LL GPPG GKTL+A+A+A E + F GSE ++G GA + LF AK AP +I
Sbjct: 122 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVI 181
Query: 238 FIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALL 297
FIDE+D++G KR++ +T+ QLLAEMDGF P V +I ATN P+ LD AL+
Sbjct: 182 FIDELDSVGGKRIESPM--HPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 239
Query: 298 RPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEA 356
RPGRFD + VP PD +GR EILK + ++K ++VD +IA T G SGA+L+ + +A
Sbjct: 240 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQA 299
Query: 357 GMFAIRERRTYVTQEDFLKAVDKVL-GNERKLLQ 389
+ A + + VT ++ + DK+L G ER+ ++
Sbjct: 300 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVE 333
>gi|7657689 YME1 (S.cerevisiae)-like 1 [Homo sapiens]
>gi|5689742|emb|CAB51858.1| (AJ132637) ATP-dependent
metalloprotease YME1L [Homo sapiens]
Length = 716
Score = 201 bits (506), Expect = 1e-50
Identities = 115/274 (41%), Positives = 169/274 (60%), Gaps = 12/274 (4%)
Query: 118 LPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGV 177
L S+ DP ++ NVT+ + G+++ QEL+E +E LK+P+ F +G PKG+
Sbjct: 267 LDSAVDP-------VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGI 318
Query: 178 LLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTII 237
LL GPPG GKTL+A+A+A E + F GSE ++G GA + LF AK AP +I
Sbjct: 319 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVI 378
Query: 238 FIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALL 297
FIDE+D++G KR++ +T+ QLLAEMDGF P V +I ATN P+ LD AL+
Sbjct: 379 FIDELDSVGGKRIESPM--HPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 436
Query: 298 RPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEA 356
RPGRFD + VP PD +GR EILK + ++K ++VD +IA T G SGA+L+ + +A
Sbjct: 437 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQA 496
Query: 357 GMFAIRERRTYVTQEDFLKAVDKVL-GNERKLLQ 389
+ A + + VT ++ + DK+L G ER+ ++
Sbjct: 497 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVE 530
>emb|CAB99462.1| (AJ295618) putative ATPases [Homo sapiens]
Length = 517
Score = 201 bits (506), Expect = 1e-50
Identities = 115/274 (41%), Positives = 169/274 (60%), Gaps = 12/274 (4%)
Query: 118 LPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGV 177
L S+ DP ++ NVT+ + G+++ QEL+E +E LK+P+ F +G PKG+
Sbjct: 70 LDSAVDP-------VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGI 121
Query: 178 LLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTII 237
LL GPPG GKTL+A+A+A E + F GSE ++G GA + LF AK AP +I
Sbjct: 122 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGATRIRNLFREAKANAPCVI 181
Query: 238 FIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALL 297
FIDE+D++G KR++ +T+ QLLAEMDGF P V +I ATN P+ LD AL+
Sbjct: 182 FIDELDSVGGKRIESPM--HPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 239
Query: 298 RPGRFDRLIEVPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEA 356
RPGRFD + VP PD +GR EILK + ++K ++VD +IA T G SGA+L+ + +A
Sbjct: 240 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQA 299
Query: 357 GMFAIRERRTYVTQEDFLKAVDKVL-GNERKLLQ 389
+ A + + VT ++ + DK+L G ER+ ++
Sbjct: 300 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVE 333
>emb|CAA54091.1| (X76643) Afg3p [Saccharomyces cerevisiae]
Length = 761
Score = 200 bits (504), Expect = 2e-50
Identities = 112/268 (41%), Positives = 158/268 (58%), Gaps = 10/268 (3%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+++ ++ G + QE+ E + LK+P + ++G P+G +L GPPG GKTL+AKA A
Sbjct: 285 ISFKNVAGCDEAKQEIMEFVHF-LKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAG 343
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR--MDETT 254
E N F+ V GSE V ++G GA V +LF A+ AP+IIFIDEIDAIG +R
Sbjct: 344 EANVPFLSVSGSEFVEMFVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALG 403
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
G E RTL QLL EMDGF V V+A TNRPD+LD AL+RPGRFDR I++ PD
Sbjct: 404 GANDERERTLNQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVN 463
Query: 315 GRLEILKVHTRRMKLKNV---DLR----VIAEITEGASGADLKAIATEAGMFAIRERRTY 367
GR +I VH +R+ L + D+ +A +T G +GAD+ EA + A R Y
Sbjct: 464 GRQQIYLVHLKRLNLDPLLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPY 523
Query: 368 VTQEDFLKAVDKVLGNERKLLQQITSHE 395
+T F +A+++V+ K + ++ E
Sbjct: 524 ITIHHFEQAIERVIAGLEKKTRVLSKEE 551
>gb|AAK42565.1| AAA family ATPase [Sulfolobus solfataricus]
Length = 607
Score = 199 bits (502), Expect = 3e-50
Identities = 111/262 (42%), Positives = 165/262 (62%), Gaps = 8/262 (3%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+T NDIGG + EL+E +EL L H +L E++ + P +G+LLYGPPG GKT+MAKALA
Sbjct: 341 LTLNDIGGYNEIKTELKELLELQLYHYKLLEQLRVPPIRGILLYGPPGVGKTMMAKALAK 400
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGG 256
+N I + G+E++ K + E+F A+E P II +DE+DAI +KR ++ G
Sbjct: 401 TLNVKLIALSGAEIMYKGYEGAIAAIKEVFNRARENKPAIILLDELDAIASKRSYKSYG- 459
Query: 257 EREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
+ ++ + QLL EMDG V VI TNR +DPALLRPGRFD++I +PLP+ E R
Sbjct: 460 --DSSKIVNQLLTEMDGIRSLKEVVVIGTTNRLKAIDPALLRPGRFDKIIHMPLPNREER 517
Query: 317 LEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIR-----ERRTYVTQE 371
L+IL + + + + VD ++A+ TEG SGADL A+A EA M ++ E +T+E
Sbjct: 518 LDILMKYIGKEECEKVDCGILADQTEGYSGADLAALAREAKMKVLKSILRGESNRTLTRE 577
Query: 372 DFLKAVDKVLGNERKLLQQITS 393
D + A++K+ + +K L + +S
Sbjct: 578 DLIDALNKIHPSVKKRLSKGSS 599
Score = 197 bits (496), Expect = 2e-49
Identities = 110/254 (43%), Positives = 156/254 (61%), Gaps = 8/254 (3%)
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
IE +T++DIGG + +E+RE IELPLK+ ++ + G+ PPKG+LL+GPPGCGKT+M
Sbjct: 53 IEDKKITWDDIGGYEDAKKEIREYIELPLKNKDVATKYGLKPPKGMLLFGPPGCGKTMMM 112
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
+ALA+E F+ V S+++ K+ GE + ELF A++ AP I+F DEID IG KR
Sbjct: 113 RALANESKLNFLYVNISDIMSKWYGESEARLRELFNNARKNAPCILFFDEIDTIGVKRES 172
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
T G+ R L +L+E+DG V V+ +TN P +LD ALLR GRFD+LI + P
Sbjct: 173 HT--GDSVTPRLLSLMLSEIDGLHSEDGVIVVGSTNVPQMLDKALLRAGRFDKLIYIGPP 230
Query: 312 DFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRE-----RR 365
+ E R +IL++H R L ++VD +AEITE SGADL + EA E
Sbjct: 231 NKEARKQILQIHCRGKPLAEDVDFDKLAEITERYSGADLANLCQEAARKVASEAIEKGAD 290
Query: 366 TYVTQEDFLKAVDK 379
+T DF++ + K
Sbjct: 291 RKITMADFIELIKK 304
>emb|CAA56963.1| (X81072) YTA7 [Saccharomyces cerevisiae]
Length = 1379
Score = 199 bits (500), Expect = 6e-50
Identities = 114/282 (40%), Positives = 171/282 (60%), Gaps = 21/282 (7%)
Query: 119 PSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVL 178
P D LG ++ NV ++DIGGL + +L+E + LPL +PEL++ I PP+GVL
Sbjct: 396 PEIADLDPLGVDM----NVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGVL 451
Query: 179 LYGPPGCGKTLMAKALA-----HEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKA 233
+GPPG GKTLMA+ALA E TF G++++ K++GE R + LFE AK+
Sbjct: 452 FHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRLLFEEAKKHQ 511
Query: 234 PTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ-LLAEMDGFDPRGNVKVIAATNRPDIL 292
P+IIF DEID + R + + +++ +++ LLA MDG D RG V VI ATNRPD +
Sbjct: 512 PSIIFFDEIDGLAPVRSSK----QEQIHASIVSTLLALMDGMDNRGQVIVIGATNRPDAV 567
Query: 293 DPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMK--LKNVDLRVIAEITEGASGADLK 350
DPAL RPGRFDR PLPD + R +IL++ TR+ L + +A +T+G GADL+
Sbjct: 568 DPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGYGGADLR 627
Query: 351 AIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQIT 392
++ TEA + +I+ + + + DK+L + K+ +++
Sbjct: 628 SLCTEAALISIQRSFPQIYRSN-----DKLLVDPSKIKVKVS 664
>gi|6321709 26S proteasome ATPase; Yta7p [Saccharomyces cerevisiae]
>gi|1729862|sp|P40340|TBP7_YEAST TAT-BINDING HOMOLOG 7
>gi|2133219|pir||S64603 YTA7 protein - yeast
(Saccharomyces cerevisiae) >gi|1323491|emb|CAA97300.1|
(Z73055) ORF YGR270w [Saccharomyces cerevisiae]
>gi|1556439|emb|CAA69201.1| (Y07893) yta7 [Saccharomyces
cerevisiae]
Length = 1379
Score = 199 bits (500), Expect = 6e-50
Identities = 114/282 (40%), Positives = 171/282 (60%), Gaps = 21/282 (7%)
Query: 119 PSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVL 178
P D LG ++ NV ++DIGGL + +L+E + LPL +PEL++ I PP+GVL
Sbjct: 396 PEIADLDPLGVDM----NVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGVL 451
Query: 179 LYGPPGCGKTLMAKALA-----HEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKA 233
+GPPG GKTLMA+ALA E TF G++++ K++GE R + LFE AK+
Sbjct: 452 FHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRLLFEEAKKHQ 511
Query: 234 PTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQ-LLAEMDGFDPRGNVKVIAATNRPDIL 292
P+IIF DEID + R + + +++ +++ LLA MDG D RG V VI ATNRPD +
Sbjct: 512 PSIIFFDEIDGLAPVRSSK----QEQIHASIVSTLLALMDGMDNRGQVIVIGATNRPDAV 567
Query: 293 DPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMK--LKNVDLRVIAEITEGASGADLK 350
DPAL RPGRFDR PLPD + R +IL++ TR+ L + +A +T+G GADL+
Sbjct: 568 DPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGYGGADLR 627
Query: 351 AIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQIT 392
++ TEA + +I+ + + + DK+L + K+ +++
Sbjct: 628 SLCTEAALISIQRSFPQIYRSN-----DKLLVDPSKIKVKVS 664
>pir||A70632 hypothetical protein Rv0435c - Mycobacterium tuberculosis (strain
H37RV) >gi|1817701|emb|CAB06575.1| (Z84724) hypothetical
protein Rv0435c [Mycobacterium tuberculosis]
Length = 728
Score = 199 bits (500), Expect = 6e-50
Identities = 115/293 (39%), Positives = 167/293 (56%), Gaps = 23/293 (7%)
Query: 84 PRFVVR-IAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERP------- 135
P FVV +A + LR +R + D R P +LG + RP
Sbjct: 402 PGFVVADLAALVREAALRAASRASADGRP-------PMLHQDDLLGALTVIRPLSRSASD 454
Query: 136 -----NVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLM 190
+VT +D+G + Q L EA+ PL+HP+ F +G++PP+GVLLYGPPGCGKT +
Sbjct: 455 EVTVGDVTLDDVGDMAAAKQALTEAVLWPLQHPDTFARLGVEPPRGVLLYGPPGCGKTFV 514
Query: 191 AKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRM 250
+ALA + V GSEL+ K++G + V ELF A++ AP+++F+DE+DA+ +R
Sbjct: 515 VRALASTGQLSVHAVKGSELMDKWVGSSEKAVRELFRRARDSAPSLVFLDELDALAPRRG 574
Query: 251 DETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL 310
G + R + LL E+DG DP +V ++ ATNRPD++DPALLRPGR +RL+ V
Sbjct: 575 QSFDSGVSD--RVVAALLTELDGIDPLRDVVMLGATNRPDLIDPALLRPGRLERLVFVEP 632
Query: 311 PDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIR 362
PD R EIL+ + + L +VDL +A +G S AD A+ EA + A+R
Sbjct: 633 PDAAARREILRTAGKSIPLSSDVDLDEVAAGLDGYSAADCVALLREAALTAMR 685
Score = 80.0 bits (194), Expect = 4e-14
Identities = 68/284 (23%), Positives = 121/284 (41%), Gaps = 18/284 (6%)
Query: 118 LPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGV 177
+P++ + G I P + ++ G + Q +L E ++L L P L + +G GV
Sbjct: 191 VPAAMGTSTAGQVSISSPEIQIEELKGAQPQAAKLTEWLKLALDEPHLLQTLGAGTNLGV 250
Query: 178 LLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTII 237
L+ GP G GK + +A+ + + G E+ G+ + V + + + ++
Sbjct: 251 LVSGPAGVGKATLVRAVCD--GRRLVTLDGPEIGALAAGDRVKAVASAVQAVRHEGG-VL 307
Query: 238 FIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALL 297
I + DA+ + +L+E+ V +IA + RPD LD L
Sbjct: 308 LITDADALLPAAAEPVAS----------LILSELRTAVATAGVVLIATSARPDQLDARLR 357
Query: 298 RPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAG 357
P DR + +PLPD R +L+ + +++L IA T G ADL A+ EA
Sbjct: 358 SPELCDRELGLPLPDAATRKSLLEALLNPVPTGDLNLDEIASRTPGFVVADLAALVREAA 417
Query: 358 MFAIRE-----RRTYVTQEDFLKAVDKVLGNERKLLQQITSHEI 396
+ A R + Q+D L A+ + R ++T ++
Sbjct: 418 LRAASRASADGRPPMLHQDDLLGALTVIRPLSRSASDEVTVGDV 461
>gi|4507173 paraplegin [Homo sapiens] >gi|3273089|emb|CAA76314.1| (Y16610)
paraplegin [Homo sapiens]
Length = 795
Score = 198 bits (499), Expect = 8e-50
Identities = 114/263 (43%), Positives = 157/263 (59%), Gaps = 5/263 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V++ D+ G+ + E+RE ++ LK PE F ++G PKG LL GPPGCGKTL+AKA+A
Sbjct: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTG- 255
E F+ + G E V G GA V LF+ A+ +AP I++IDEIDA+G KR +G
Sbjct: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
E +TL QLL EMDG +V V+A+TNR DILD AL+RPGR DR + + LP +
Sbjct: 425 SNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQE 484
Query: 316 RLEILKVHTRRMKLKNVDL---RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
R EI + H + +KL + +AE+T G SGAD+ I EA + A RE T V +
Sbjct: 485 RREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLN 544
Query: 373 FLKAVDKVLGNERKLLQQITSHE 395
F AV++VL K + ++ E
Sbjct: 545 FEYAVERVLAGTAKKSKILSKEE 567
>gb|AAD28099.1| (AF080525) paraplegin [Homo sapiens]
Length = 795
Score = 198 bits (499), Expect = 8e-50
Identities = 114/263 (43%), Positives = 157/263 (59%), Gaps = 5/263 (1%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
V++ D+ G+ + E+RE ++ LK PE F ++G PKG LL GPPGCGKTL+AKA+A
Sbjct: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTG- 255
E F+ + G E V G GA V LF+ A+ +AP I++IDEIDA+G KR +G
Sbjct: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
Query: 256 GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEG 315
E +TL QLL EMDG +V V+A+TNR DILD AL+RPGR DR + + LP +
Sbjct: 425 SNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQE 484
Query: 316 RLEILKVHTRRMKLKNVDL---RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQED 372
R EI + H + +KL + +AE+T G SGAD+ I EA + A RE T V +
Sbjct: 485 RREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLN 544
Query: 373 FLKAVDKVLGNERKLLQQITSHE 395
F AV++VL K + ++ E
Sbjct: 545 FEYAVERVLAGTAKKSKILSKEE 567
>gi|6320854 ATP-dependent metalloprotease; Afg3p [Saccharomyces cerevisiae]
>gi|728820|sp|P39925|AFG3_YEAST MITOCHONDRIAL
RESPIRATORY CHAIN COMPLEXES ASSEMBLY PROTEIN AFG3
(TAT-BINDING HOMOLOG 10) >gi|626985|pir||S46611 YTA10
protein - yeast (Saccharomyces cerevisiae)
>gi|531750|emb|CAA56953.1| (X81066) probable
mitochondrial protein [Saccharomyces cerevisiae]
>gi|603609|gb|AAB64550.1| (U18778) Afg3p [Saccharomyces
cerevisiae]
Length = 761
Score = 198 bits (498), Expect = 1e-49
Identities = 111/268 (41%), Positives = 157/268 (58%), Gaps = 10/268 (3%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+++ ++ G + QE+ E + LK+P + ++G P+G +L GPPG GKTL+AKA A
Sbjct: 285 ISFKNVAGCDEAKQEIMEFVHF-LKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAG 343
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR--MDETT 254
E N F+ V GSE V ++G GA V +LF A+ AP+IIFIDEIDAIG +R
Sbjct: 344 EANVPFLSVSGSEFVEMFVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALG 403
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
G E TL QLL EMDGF V V+A TNRPD+LD AL+RPGRFDR I++ PD
Sbjct: 404 GANDEREATLNQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVN 463
Query: 315 GRLEILKVHTRRMKLKNV---DLR----VIAEITEGASGADLKAIATEAGMFAIRERRTY 367
GR +I VH +R+ L + D+ +A +T G +GAD+ EA + A R Y
Sbjct: 464 GRQQIYLVHLKRLNLDPLLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPY 523
Query: 368 VTQEDFLKAVDKVLGNERKLLQQITSHE 395
+T F +A+++V+ K + ++ E
Sbjct: 524 ITIHHFEQAIERVIAGLEKKTRVLSKEE 551
>pir||S52928 XSUG1 protein - African clawed frog
Length = 283
Score = 198 bits (498), Expect = 1e-49
Identities = 111/256 (43%), Positives = 159/256 (61%), Gaps = 10/256 (3%)
Query: 21 YLKRRIRQLELQV-------RMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDD 73
Y +I L+L V R L+A + L ++ LR E+ L++ +
Sbjct: 18 YYLSKIEDLQLVVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGILRRRSGQSYGQ 77
Query: 74 DRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE 133
+ ++ Q G +FVV + I+ + + P RVAL + + ++LP+ DP V V +
Sbjct: 78 EESVGQGSPGGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEK 137
Query: 134 RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKA 193
P+ TY IGGL KQ++E++E IELP+KHPE FE +GI PKGVLLYGPPG GKTL+A+A
Sbjct: 138 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPEHFEALGIAQPKGVLLYGPPGTGKTLLARA 197
Query: 194 LAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
+AH + TFIRV GSELV+K+IGEGAR+V ELF +A+E AP+IIF+DEID+IG++ +
Sbjct: 198 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSR---GS 254
Query: 254 TGGEREVNRTLMQLLA 269
G E R+ Q L+
Sbjct: 255 RGAREETARSSAQCLS 270
>gi|6322994 Yll034cp [Saccharomyces cerevisiae]
>gi|2492526|sp|Q07844|YL34_YEAST HYPOTHETICAL 93.1 KD
PROTEIN YLL034C >gi|2131732|pir||S64785 hypothetical
protein YLL034c - yeast (Saccharomyces cerevisiae)
>gi|1360222|emb|CAA97483.1| (Z73139) ORF YLL034c
[Saccharomyces cerevisiae]
Length = 837
Score = 198 bits (497), Expect = 1e-49
Identities = 113/276 (40%), Positives = 165/276 (58%), Gaps = 13/276 (4%)
Query: 128 GFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGK 187
GF + P+VT+ ++G L++ EL AI P+K PEL+E+VGI P GVLL+GPPGCGK
Sbjct: 523 GFATV--PDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGVLLWGPPGCGK 580
Query: 188 TLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGA 247
TL+AKA+A+E A FI + G EL+ KY+GE R + ++F A+ P +IF DE+DA+
Sbjct: 581 TLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDELDALVP 640
Query: 248 KRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIE 307
+R T +R + LL E+DG + R + VI ATNRPD++DPA+LRPGR D+ +
Sbjct: 641 RR---DTSLSESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMIDPAMLRPGRLDKSLF 697
Query: 308 VPLPDFEGRLEILKVHTRRMKL---KNVDLRVIA--EITEGASGADLKAIATEAGMFAIR 362
+ LP+ E +L+I+K T+ +VD I E SGADL A+ E+ + A+
Sbjct: 698 IELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADLAALVRESSVLAL- 756
Query: 363 ERRTYVTQEDFLKAVDKVLGNE-RKLLQQITSHEII 397
+R + E+ +D L E L ++ EII
Sbjct: 757 -KRKFFQSEEIQSVLDNDLDKEFEDLSVGVSGEEII 791
Score = 179 bits (450), Expect = 4e-44
Identities = 102/234 (43%), Positives = 141/234 (59%), Gaps = 9/234 (3%)
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
PN + +GG+ + +L E I LP+ HPE+F G++PP+GVLL+GPPGCGKT +A AL
Sbjct: 200 PNSSLKSLGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANAL 259
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
A E+ FI + +V GE + + +LF+ A+ AP ++F DEIDAI KR
Sbjct: 260 AGELQVPFISISAPSVVSGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKR---DG 316
Query: 255 GGEREVNRTLM-QLLAEMDGFDPRGN----VKVIAATNRPDILDPALLRPGRFDRLIEVP 309
G +RE+ R ++ QLL MD V +I ATNRPD LD AL R GRFDR I +
Sbjct: 317 GAQREMERRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLN 376
Query: 310 LPDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAIATEAGMFAIR 362
+P+ RL ILK + +K+ +D +A++T G GADLKA+ T AG AI+
Sbjct: 377 VPNEVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIK 430
>gb|AAF47769.1| (AE003478) CG12010 gene product [Drosophila melanogaster]
Length = 736
Score = 187 bits (469), Expect = 3e-46
Identities = 107/264 (40%), Positives = 159/264 (59%), Gaps = 7/264 (2%)
Query: 132 IERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMA 191
+ + + IGG++ + L+ ++ ++ F G+ PKGVLLYGPPGC KT +A
Sbjct: 461 VSKMTAGFEVIGGMEALKRTLQVSVLAGIRQSAAFARFGLSLPKGVLLYGPPGCAKTTVA 520
Query: 192 KALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD 251
K LA E + TFI +E+ Y+G R + +F+ A++ AP +IF+DEID++ +R
Sbjct: 521 KCLAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRTV 580
Query: 252 ETTGGEREVN-RTLMQLLAEMDGFDPRG---NVKVIAATNRPDILDPALLRPGRFDRLIE 307
+ GG +V R L LL EM+G G ++ V+AATNRPD++D ALLRPGRFD+LI
Sbjct: 581 SSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIH 640
Query: 308 VPLPDFEGRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRT 366
VP PD + RL +LK+H++RM +NV L+ IA T+ SGADL + EA + A +R
Sbjct: 641 VPAPDEKSRLALLKLHSQRMPFHENVFLQEIAARTDRYSGADLCNLCNEAAIEAF--QRD 698
Query: 367 YVTQEDFLKAVDKVLGNERKLLQQ 390
+ E L+ +KVL ++ L Q
Sbjct: 699 FKATEIELQDFEKVLTKQKSSLTQ 722
>sp|Q13608|PEX6_HUMAN PEROXISOME ASSEMBLY FACTOR-2 (PAF-2) (PEROXISOMAL-TYPE ATPASE 1)
(PEROXIN-6) >gi|2135899|pir||S71090 peroxisome
biogenesis disorder group 4 protein PXAAA1 - human
>gi|1354753|gb|AAC50655.1| (U56602) Pxaaa1p [Homo
sapiens]
Length = 980
Score = 177 bits (445), Expect = 2e-43
Identities = 109/258 (42%), Positives = 160/258 (61%), Gaps = 7/258 (2%)
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P+V+++D+GGL++ +E+ E I+LPL+HPEL +G+ G+LL+GPPG GKTL+AKA+
Sbjct: 700 PSVSWHDVGGLQEVKKEILETIQLPLEHPELLS-LGLRR-SGLLLHGPPGTGKTLLAKAV 757
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
A E + TF+ V G EL+ Y+G+ V E+F A+ AP IIF DE+D++ R
Sbjct: 758 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGD 817
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL-PDF 313
G ++R + QLLAE+DG +V VI ATNRPD+LDPALLRPGRFD+L+ V D
Sbjct: 818 SG-GVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANEDR 876
Query: 314 EGRLEILKVHTRRMKLK-NVDL-RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+L +L TR+ KL+ +V L V+ +GADL ++ ++A M A +RR + +E
Sbjct: 877 ASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDA-MTAALKRRVHDLEE 935
Query: 372 DFLKAVDKVLGNERKLLQ 389
++ LLQ
Sbjct: 936 GLEPGSSALMLTMEDLLQ 953
>gi|4505729 peroxisomal biogenesis factor 6; Peroxisomal biogenesis factor 6
(peroxisomal AAA-type ATPase 1); peroxisome biogenesis
factor 6 [Homo sapiens] >gi|1747316|dbj|BAA12069.1|
(D83703) peroxisome assembly factor-2 [Homo sapiens]
>gi|7453117|gb|AAF62564.1| (AF108098) peroxisome
assembly factor-2 [Homo sapiens]
Length = 980
Score = 177 bits (445), Expect = 2e-43
Identities = 109/258 (42%), Positives = 160/258 (61%), Gaps = 7/258 (2%)
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P+V+++D+GGL++ +E+ E I+LPL+HPEL +G+ G+LL+GPPG GKTL+AKA+
Sbjct: 700 PSVSWHDVGGLQEVKKEILETIQLPLEHPELLS-LGLRR-SGLLLHGPPGTGKTLLAKAV 757
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
A E + TF+ V G EL+ Y+G+ V E+F A+ AP IIF DE+D++ R
Sbjct: 758 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGD 817
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL-PDF 313
G ++R + QLLAE+DG +V VI ATNRPD+LDPALLRPGRFD+L+ V D
Sbjct: 818 SG-GVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANEDR 876
Query: 314 EGRLEILKVHTRRMKLK-NVDL-RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+L +L TR+ KL+ +V L V+ +GADL ++ ++A M A +RR + +E
Sbjct: 877 ASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDA-MTAALKRRVHDLEE 935
Query: 372 DFLKAVDKVLGNERKLLQ 389
++ LLQ
Sbjct: 936 GLEPGSSALMLTMEDLLQ 953
>gi|11417640 peroxisomal biogenesis factor 6 [Homo sapiens]
Length = 600
Score = 177 bits (445), Expect = 2e-43
Identities = 109/258 (42%), Positives = 160/258 (61%), Gaps = 7/258 (2%)
Query: 135 PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAL 194
P+V+++D+GGL++ +E+ E I+LPL+HPEL +G+ G+LL+GPPG GKTL+AKA+
Sbjct: 320 PSVSWHDVGGLQEVKKEILETIQLPLEHPELLS-LGLRR-SGLLLHGPPGTGKTLLAKAV 377
Query: 195 AHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETT 254
A E + TF+ V G EL+ Y+G+ V E+F A+ AP IIF DE+D++ R
Sbjct: 378 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGD 437
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPL-PDF 313
G ++R + QLLAE+DG +V VI ATNRPD+LDPALLRPGRFD+L+ V D
Sbjct: 438 SG-GVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANEDR 496
Query: 314 EGRLEILKVHTRRMKLK-NVDL-RVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+L +L TR+ KL+ +V L V+ +GADL ++ ++A M A +RR + +E
Sbjct: 497 ASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDA-MTAALKRRVHDLEE 555
Query: 372 DFLKAVDKVLGNERKLLQ 389
++ LLQ
Sbjct: 556 GLEPGSSALMLTMEDLLQ 573
>dbj|BAB00559.1| (AP001299) contains similarity to 26S proteasome subunit
4~gene_id:F4B12.4 [Arabidopsis thaliana]
Length = 1964
Score = 175 bits (439), Expect = 8e-43
Identities = 101/264 (38%), Positives = 153/264 (57%), Gaps = 12/264 (4%)
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
++ + GL+ Q ++E + +PL +PE F+ +G+ PP+G+LL+G PG GKTL+ +AL +
Sbjct: 728 WDSVAGLEGVTQCMKEVVLIPLLYPEFFDNLGLTPPRGILLHGHPGTGKTLVVRALIGSL 787
Query: 199 NATFIRVV-----GSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDET 253
R+ G++ + KY+G+ R + LF++A++ P+IIF DEID + KR +
Sbjct: 788 ARGNRRIAYFARKGADCLGKYVGDAERQLRLLFQVAEKCQPSIIFFDEIDGLAPKRSRQQ 847
Query: 254 TGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 313
V TL+ LL DG RG+V VI ATN PD +DPAL RPGRFDR I PLP
Sbjct: 848 DQTHSSVVSTLLALL---DGLKSRGSVVVIGATNYPDAIDPALRRPGRFDREIYFPLPSV 904
Query: 314 EGRLEILKVHTRR--MKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQE 371
+ R I+ +HTR+ + L+ IA+ T G +GAD++A+ T+A M A+ R++ QE
Sbjct: 905 DDRAAIISLHTRKWPKPVSGYLLKWIAKETAGFAGADIQALCTQAAMIAL--NRSFPLQE 962
Query: 372 DFLKAVDKVLGNERKLLQQITSHE 395
A V + R L + E
Sbjct: 963 SLAAAELGVSSSNRAALPSFSVEE 986
>pir||E64486 ATP-dependent 26S proteosome regulatory subunit 8 homolog -
Methanococcus jannaschii
Length = 373
Score = 173 bits (434), Expect = 3e-42
Identities = 100/234 (42%), Positives = 148/234 (62%), Gaps = 9/234 (3%)
Query: 160 LKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGA 219
L++P+LF E PK VL YGPPG GKTLMA+ALA E N++FI V EL+ +++G+ +
Sbjct: 145 LENPKLFGEWA---PKNVLFYGPPGTGKTLMARALATETNSSFILVKAPELIGEHVGDAS 201
Query: 220 RLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGN 279
+++ EL++ A E AP I+FIDE+DAIG R ++ G +V+ + LL E+DG
Sbjct: 202 KMIRELYQRASESAPCIVFIDELDAIGLSREYQSLRG--DVSEVVNALLTELDGIKENEG 259
Query: 280 VKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIA 338
V IAATN P +LDPA+ RF+ IE LP+ E RL+I++++ ++M L +L+
Sbjct: 260 VVTIAATNNPAMLDPAI--RSRFEEEIEFKLPNDEERLKIMELYAKKMPLPVKANLKEFV 317
Query: 339 EITEGASGADLKAIATEAGMF-AIRERRTYVTQEDFLKAVDKVLGNERKLLQQI 391
E T+G SG D+K + + AI E R YV++ED A+ K+LGN R+ Q +
Sbjct: 318 EKTKGFSGRDIKEKFLKPALHRAILEDRDYVSKEDLEWALKKILGNRREAPQHL 371
>sp|Q58889|PRS2_METJA PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HOMOLOG MJ1494
>gi|2826420|gb|AAB99505.1| (U67590) AAA superfamily
ATPase, similar to FtsH [Methanococcus jannaschii]
Length = 371
Score = 173 bits (434), Expect = 3e-42
Identities = 100/234 (42%), Positives = 148/234 (62%), Gaps = 9/234 (3%)
Query: 160 LKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGA 219
L++P+LF E PK VL YGPPG GKTLMA+ALA E N++FI V EL+ +++G+ +
Sbjct: 143 LENPKLFGEWA---PKNVLFYGPPGTGKTLMARALATETNSSFILVKAPELIGEHVGDAS 199
Query: 220 RLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGN 279
+++ EL++ A E AP I+FIDE+DAIG R ++ G +V+ + LL E+DG
Sbjct: 200 KMIRELYQRASESAPCIVFIDELDAIGLSREYQSLRG--DVSEVVNALLTELDGIKENEG 257
Query: 280 VKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK-NVDLRVIA 338
V IAATN P +LDPA+ RF+ IE LP+ E RL+I++++ ++M L +L+
Sbjct: 258 VVTIAATNNPAMLDPAI--RSRFEEEIEFKLPNDEERLKIMELYAKKMPLPVKANLKEFV 315
Query: 339 EITEGASGADLKAIATEAGMF-AIRERRTYVTQEDFLKAVDKVLGNERKLLQQI 391
E T+G SG D+K + + AI E R YV++ED A+ K+LGN R+ Q +
Sbjct: 316 EKTKGFSGRDIKEKFLKPALHRAILEDRDYVSKEDLEWALKKILGNRREAPQHL 369
>pir||T03904 hypothetical protein F39G3.7 - Caenorhabditis elegans
>gi|7511608|pir||T37276 protein PEX6 homolog -
Caenorhabditis elegans >gi|7511609|pir||T37307 protein
Pex6p homolog - Caenorhabditis elegans
>gi|2291210|gb|AAB65332.1| (AF016424) contains
similarity to the AAA family of ATPases [Caenorhabditis
elegans] >gi|3721554|dbj|BAA33544.1| (AB010968) PEX6
[Caenorhabditis elegans] >gi|4586630|dbj|BAA76440.1|
(AB012224) Pex6p homolog [Caenorhabditis elegans]
Length = 720
Score = 171 bits (428), Expect = 2e-41
Identities = 119/315 (37%), Positives = 182/315 (57%), Gaps = 23/315 (7%)
Query: 95 ERDKL-RPGARVALDQRTMAIIELLPSSKDPT---VLGFEVIERPNVTYNDIGGLKKQLQ 150
E +KL + G +V ++++ + E L ++ +G I PNV + D+GGL++ Q
Sbjct: 418 ELEKLVKNGKKVKIEEKEEKVYEDLIDKRNSNFADAIGAPKI--PNVRWEDVGGLEETKQ 475
Query: 151 ELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSEL 210
+ E+I L + G++LYG PGCGKTL+AKA+A E F+ V G EL
Sbjct: 476 TVLESIRTNLFGSRALKR------SGIILYGSPGCGKTLIAKAVATEFKIAFLSVKGPEL 529
Query: 211 VRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR-MDETTGGEREVNRTLMQLLA 269
+ KY+G+ + ++FE AK+ +P +IF DEID++ R + +GG ++R + QLLA
Sbjct: 530 LNKYVGQSEENLRKVFERAKQASPCVIFFDEIDSLAPNRGRNGDSGG--VIDRIVSQLLA 587
Query: 270 EMDGF--DPRGNVKVIAATNRPDILDPALLRPGRFDRLIEV-PLPDFEGRLEILKVHTRR 326
E+D P V V+ ATNRPD+LD +L+ PGRFD+L+EV P D E + +IL+ +R+
Sbjct: 588 ELDKLHNSPLTKVFVMGATNRPDLLDNSLMTPGRFDKLVEVKPGEDVESKTKILEAVSRK 647
Query: 327 MKL-KNVDLRVIA-EITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNE 384
M+ ++VDLR IA ++ E SGA L +I + AGM AI E T + ED + +
Sbjct: 648 MRFEEDVDLREIASKVDEKMSGAQLFSIISNAGMAAIVE--TIQSIEDGKTENQSIRVAQ 705
Query: 385 RKLLQQITS-HEIIY 398
R LL+ + HE Y
Sbjct: 706 RHLLESVKRFHETKY 720
>gi|6325183 Yta6p [Saccharomyces cerevisiae] >gi|2133218|pir||S61113 YTA6
protein - yeast (Saccharomyces cerevisiae)
>gi|1147619|gb|AAB68264.1| (U41849) Yta6p [Saccharomyces
cerevisiae]
Length = 754
Score = 167 bits (419), Expect = 2e-40
Identities = 107/275 (38%), Positives = 157/275 (56%), Gaps = 18/275 (6%)
Query: 126 VLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGC 185
+L ++ V + DI GL+ L+EA+ P P+LF+ + +P +G+LL+GPPG
Sbjct: 457 ILNEILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLR-EPVRGMLLFGPPGT 515
Query: 186 GKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAI 245
GKT++AKA+A E N+TF V S L+ KY+GE +LV LF +AK+ +P+IIFIDEID++
Sbjct: 516 GKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSM 575
Query: 246 GAKRMDETTGGEREVNRTLM----QLLAEMDGFDPRGN-----VKVIAATNRPDILDPAL 296
R D R + L+ L + + R N V V+ ATN P +D A
Sbjct: 576 LTARSDNENESSRRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAA 635
Query: 297 LRPGRFDRLIEVPLPDFEGRLEILK--VHTRRMKLKNVDLRVIAEITEGASGADLKAIAT 354
R RF R + +PLPD+E RL LK + ++ L+++D +I E+TEG SG+DL ++A
Sbjct: 636 RR--RFSRKLYIPLPDYETRLYHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAK 693
Query: 355 EAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQ 389
EA M IR+ + DF DK+ G E K Q
Sbjct: 694 EAAMEPIRDLGDKLMFADF----DKIRGIEIKDFQ 724
>pir||T50122 vesicular transport protein sec18 homolog [imported] - fission
yeast (Schizosaccharomyces pombe)
>gi|7019771|emb|CAB75779.1| (AL157734) putative
vesicular transport and membrane fusion protein; sec18
homolog [Schizosaccharomyces pombe]
Length = 792
Score = 161 bits (402), Expect = 2e-38
Identities = 106/286 (37%), Positives = 157/286 (54%), Gaps = 20/286 (6%)
Query: 132 IERPNVTYND--IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKT 188
I +P + D IGGL + + R A L P + E++GI+ KG+LLYGPPG GKT
Sbjct: 259 ILQPGFKFEDMGIGGLDSEFSAIFRRAFASRLFPPGMVEKLGINHVKGILLYGPPGTGKT 318
Query: 189 LMAKALAHEVNATFIRVV-GSELVRKYIGEGARLVHELF--------ELAKEKAPTIIFI 239
L+A+ + +NA ++V G E++ KY+G+ V +LF + +E II
Sbjct: 319 LIARQIGKMLNAREPKIVNGPEILNKYVGQSEENVRKLFADAEREYRDRGEESGLHIIIF 378
Query: 240 DEIDAIGAKRMDETTGGEREV-NRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLR 298
DE+DAI KR ++GG+ V ++ + QLLA+MDG D N+ VI TNR D++D ALLR
Sbjct: 379 DELDAICKKR--GSSGGDTGVGDQVVNQLLAKMDGVDQLNNILVIGMTNRKDMIDEALLR 436
Query: 299 PGRFDRLIEVPLPDFEGRLEILKVHTRRMK----LKN-VDLRVIAEITEGASGADLKAIA 353
PGR + +E+ LPD GRL+ILK+HT RM L+N VD+ +A +T+ SGA++ +
Sbjct: 437 PGRLEVHMEISLPDEHGRLQILKIHTSRMASNGILENDVDMEELASLTKNFSGAEIAGLI 496
Query: 354 TEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEIIYG 399
A FA T ++ + N L ++ YG
Sbjct: 497 KSASSFAFYRHIKVGTTAAVSGNLENIKVNRNDFLNALSEVRPAYG 542
>gb|AAC46844.1| (U28836) N-ethylmaleimide sensitive fusion protein-2 [Drosophila
melanogaster]
Length = 744
Score = 155 bits (388), Expect = 8e-37
Identities = 104/290 (35%), Positives = 155/290 (52%), Gaps = 35/290 (12%)
Query: 142 IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
IGGL K+ + R A + PEL E++GI KG+LLYGPPG GKTLMA+ + +NA
Sbjct: 217 IGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNA 276
Query: 201 TFIRVV-GSELVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAIGAKRMD 251
++V G +++ KY+GE + LF A+E+ II DEIDAI K
Sbjct: 277 REPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAI-CKARG 335
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
G + + QLLA++DG + N+ VI TNR D++D ALLRPGR + +E+ LP
Sbjct: 336 SVAGNSGVHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLP 395
Query: 312 DFEGRLEILKVHTRRMK-----LKNVDLRVIAEITEGASGADLKAIATEAGMFAIRE--- 363
+ +GR++IL +HT+RM+ +VD IA T+ SGA+L+ + A A+
Sbjct: 396 NEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIK 455
Query: 364 ------------RRTYVTQEDFLKAVDK----VLGNERKLLQQITSHEII 397
+ VT+ DFL A+D G +++L+ + + II
Sbjct: 456 ADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLENLLARGII 505
>sp|P54351|NSF2_DROME VESICULAR-FUSION PROTEIN NSF2 (N-ETHYLMALEIMIDE-SENSITIVE FUSION
PROTEIN 2) (NEM-SENSITIVE FUSION PROTEIN 2) (DNSF-2)
>gi|973317|gb|AAA75044.1| (U30502) Drosophila
N-ethylmaleimide-sensitive fusion protein 2 [Drosophila
melanogaster]
Length = 752
Score = 155 bits (388), Expect = 8e-37
Identities = 104/290 (35%), Positives = 155/290 (52%), Gaps = 35/290 (12%)
Query: 142 IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
IGGL K+ + R A + PEL E++GI KG+LLYGPPG GKTLMA+ + +NA
Sbjct: 225 IGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNA 284
Query: 201 TFIRVV-GSELVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAIGAKRMD 251
++V G +++ KY+GE + LF A+E+ II DEIDAI K
Sbjct: 285 REPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAI-CKARG 343
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
G + + QLLA++DG + N+ VI TNR D++D ALLRPGR + +E+ LP
Sbjct: 344 SVAGNSGVHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLP 403
Query: 312 DFEGRLEILKVHTRRMK-----LKNVDLRVIAEITEGASGADLKAIATEAGMFAIRE--- 363
+ +GR++IL +HT+RM+ +VD IA T+ SGA+L+ + A A+
Sbjct: 404 NEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIK 463
Query: 364 ------------RRTYVTQEDFLKAVDK----VLGNERKLLQQITSHEII 397
+ VT+ DFL A+D G +++L+ + + II
Sbjct: 464 ADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLENLLARGII 513
>gb|AAF54995.1| (AE003702) Nsf2 gene product [Drosophila melanogaster]
Length = 1113
Score = 155 bits (388), Expect = 8e-37
Identities = 104/290 (35%), Positives = 155/290 (52%), Gaps = 35/290 (12%)
Query: 142 IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
IGGL K+ + R A + PEL E++GI KG+LLYGPPG GKTLMA+ + +NA
Sbjct: 586 IGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNA 645
Query: 201 TFIRVV-GSELVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAIGAKRMD 251
++V G +++ KY+GE + LF A+E+ II DEIDAI K
Sbjct: 646 REPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAI-CKARG 704
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
G + + QLLA++DG + N+ VI TNR D++D ALLRPGR + +E+ LP
Sbjct: 705 SVAGNSGVHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLP 764
Query: 312 DFEGRLEILKVHTRRMK-----LKNVDLRVIAEITEGASGADLKAIATEAGMFAIRE--- 363
+ +GR++IL +HT+RM+ +VD IA T+ SGA+L+ + A A+
Sbjct: 765 NEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIK 824
Query: 364 ------------RRTYVTQEDFLKAVDK----VLGNERKLLQQITSHEII 397
+ VT+ DFL A+D G +++L+ + + II
Sbjct: 825 ADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLENLLARGII 874
>sp|P46461|NSF1_DROME VESICULAR-FUSION PROTEIN NSF1 (N-ETHYLMALEIMIDE-SENSITIVE FUSION
PROTEIN 1) (NEM-SENSITIVE FUSION PROTEIN 1) (DNSF-1)
(COMATOSE PROTEIN) >gi|507752|gb|AAA83413.1| (U09373)
N-ethylmaleimide-sensitive fusion protein [Drosophila
melanogaster]
Length = 745
Score = 153 bits (382), Expect = 4e-36
Identities = 101/290 (34%), Positives = 155/290 (52%), Gaps = 35/290 (12%)
Query: 142 IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
IGGL K+ + R A + PEL E++G KG+LLYGPPG GKTLMA+ + +NA
Sbjct: 220 IGGLDKEFNSIFRRAFASRVFPPELVEQLGCKHVKGILLYGPPGTGKTLMARQIGTMLNA 279
Query: 201 TFIRVV-GSELVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAIGAKRMD 251
++V G +++ KY+GE V LF A+E+ II DEIDAI K+
Sbjct: 280 REPKIVNGPQILDKYVGESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAI-CKQRG 338
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
G + + QLL ++DG D N+ VI TNR D++D ALLRPGR + +E+ LP
Sbjct: 339 SVAGNSGVHDTVVNQLLTKIDGVDQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLP 398
Query: 312 DFEGRLEILKVHTRRMKLKN-----VDLRVIAEITEGASGADLKAIATEAGMFAIRE--- 363
+ +GR++IL +HT+RM+ N VD + IA +T+ SGA+L+ + A A+
Sbjct: 399 NEQGRVQILNIHTKRMREFNKINDDVDNKEIAALTKNFSGAELEGLVRAAQSSAMNRLIK 458
Query: 364 ------------RRTYVTQEDFLKAVD----KVLGNERKLLQQITSHEII 397
+ V ++DFL +++ G +++L + + +I
Sbjct: 459 ADAKVTVDPEAMEKLKVNRDDFLHSLEHDIKPAFGTAQEILDNMLARGVI 508
>gb|AAF48244.1| (AE003492) comt gene product [Drosophila melanogaster]
Length = 737
Score = 153 bits (382), Expect = 4e-36
Identities = 101/290 (34%), Positives = 155/290 (52%), Gaps = 35/290 (12%)
Query: 142 IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
IGGL K+ + R A + PEL E++G KG+LLYGPPG GKTLMA+ + +NA
Sbjct: 212 IGGLDKEFNSIFRRAFASRVFPPELVEQLGCKHVKGILLYGPPGTGKTLMARQIGTMLNA 271
Query: 201 TFIRVV-GSELVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAIGAKRMD 251
++V G +++ KY+GE V LF A+E+ II DEIDAI K+
Sbjct: 272 REPKIVNGPQILDKYVGESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAI-CKQRG 330
Query: 252 ETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLP 311
G + + QLL ++DG D N+ VI TNR D++D ALLRPGR + +E+ LP
Sbjct: 331 SVAGNSGVHDTVVNQLLTKIDGVDQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLP 390
Query: 312 DFEGRLEILKVHTRRMKLKN-----VDLRVIAEITEGASGADLKAIATEAGMFAIRE--- 363
+ +GR++IL +HT+RM+ N VD + IA +T+ SGA+L+ + A A+
Sbjct: 391 NEQGRVQILNIHTKRMREFNKINDDVDNKEIAALTKNFSGAELEGLVRAAQSSAMNRLIK 450
Query: 364 ------------RRTYVTQEDFLKAVD----KVLGNERKLLQQITSHEII 397
+ V ++DFL +++ G +++L + + +I
Sbjct: 451 ADAKVTVDPEAMEKLKVNRDDFLHSLEHDIKPAFGTAQEILDNMLARGVI 500
>pir||D75493 cell division cycle protein 48-related protein - Deinococcus
radiodurans (strain R1)
>gi|6458348|gb|AAF10225.1|AE001922_5 (AE001922) cell
division cycle protein 48-related protein [Deinococcus
radiodurans]
Length = 460
Score = 152 bits (380), Expect = 7e-36
Identities = 97/288 (33%), Positives = 148/288 (50%), Gaps = 14/288 (4%)
Query: 119 PSSKDPTVLGFEVIER-----PNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDP 173
P+ + P G + R +V+ D+ G+ + L ++ PL+HPEL + G
Sbjct: 156 PAQQQPYPTGTDFSSRWQPLAGDVSLKDVVGMTDLKERLERSLLGPLRHPELAQLYGKKS 215
Query: 174 PKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKA 233
G+LLYGPPGCGKT +A+A+A E+ A+F+ V ++++ ++G R V +LF A+ A
Sbjct: 216 GGGMLLYGPPGCGKTFLARAVAGELGASFLEVTVADVLDMWLGNAERNVRDLFASARAHA 275
Query: 234 PTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILD 293
P ++F DE+DA+G R T V +T LL E+DG R V V+AATN P +D
Sbjct: 276 PCVVFFDEVDALGRGR-QLTRHSSHSVTQT---LLRELDGLGGREGVFVLAATNAPWDVD 331
Query: 294 PALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIA 353
AL RPGR + VP PD R + R + +D +A T+ SGAD++ +
Sbjct: 332 TALKRPGRLGATLLVPPPDLAAREAMFTEFMRGRPAERLDPAWLARQTDNFSGADIRQLC 391
Query: 354 TEAGMFAI-----RERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEI 396
EA A+ R V +DF A+ + R+ L Q +H +
Sbjct: 392 EEASERALAVALKRGGMQPVRMQDFKDALKTAAPSTREWLMQARNHVV 439
>gb|AAF18300.1|AF118384_1 (AF118384) N-ethylmaleimide sensitive fusion protein [Manduca
sexta]
Length = 745
Score = 152 bits (379), Expect = 9e-36
Identities = 111/341 (32%), Positives = 176/341 (51%), Gaps = 41/341 (12%)
Query: 94 IERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYND--IGGLKKQLQE 151
+ +L P A V D+ + + L+ +K + I P+ + IGGL K+
Sbjct: 172 VRMGRLLPDASVQFDKAENSSLNLVGKAKGKQPR--QSIINPDWDFGKMGIGGLDKEFNA 229
Query: 152 L-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV-GSE 209
+ R A + PE+ E++G KG+LL+GPPG GKTLMA+ + +NA ++V G +
Sbjct: 230 IFRRAFASRVFPPEVVEQLGCKHVKGILLFGPPGTGKTLMARQIGKMLNAREPKIVNGPQ 289
Query: 210 LVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAIGAKRMDETTGGEREVN 261
++ KY+GE + LF A+E+ II DEIDAI R + GG V+
Sbjct: 290 ILDKYVGESEANIRPLFADAEEEEKRCGPNSGLHIIIFDEIDAICKAR--GSVGGNTGVH 347
Query: 262 RTLM-QLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEIL 320
T++ QLL+++DG D N+ VI TNR D++D ALLRPGR + +E+ LPD +GR++IL
Sbjct: 348 DTVVNQLLSKIDGVDQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEIGLPDEKGRVQIL 407
Query: 321 KVHTRRMK-----LKNVDLRVIAEITEGASGADLKAIATEAGMFAIRE------------ 363
+HT+RM+ ++VD +A +T+ SGA+L+ + A A+
Sbjct: 408 NIHTKRMREYKKIAEDVDSMELAALTKNFSGAELEGLVRAAQSTAMNRLIKASSKVEVDP 467
Query: 364 ---RRTYVTQEDFLKAVDK----VLGNERKLLQQITSHEII 397
+ V + DFL A++ G + L+ S +I
Sbjct: 468 EAMEKLMVERGDFLHALENDIKPAFGTAAEALEHFLSRGVI 508
>pir||S37606 SEC18 protein - yeast (Candida albicans)
Length = 794
Score = 147 bits (368), Expect = 2e-34
Identities = 97/293 (33%), Positives = 158/293 (53%), Gaps = 41/293 (13%)
Query: 142 IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
IGGL + Q++ R A + PEL E++ KG+LLYGPPG GKTL+A+ L+ +N
Sbjct: 277 IGGLDAEFQDIFRRAFNSRILPPELAEKLDYKHCKGLLLYGPPGTGKTLIARKLSKMLNG 336
Query: 201 TFIRVV-GSELVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAI----GA 247
++V G E++ KY+G + LF+ A+ + +I DE+D++ G+
Sbjct: 337 KEPKIVNGPEMLSKYVGASEENIRNLFKDAEAEYKLKGEDSDLHVIIFDELDSVFKQRGS 396
Query: 248 KRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIE 307
+ D T G+ VN QLL++MDG D N+ VI TNR D++D ALLRPGRF+ IE
Sbjct: 397 GKSDGTGVGDNVVN----QLLSKMDGVDQLNNILVIGMTNRLDLIDTALLRPGRFEIQIE 452
Query: 308 VPLPDFEGRLEILKVHTRRMK-----LKNVDLRVIAEITEGASGADLKAIATEAGMFAIR 362
+ LPD +GR +I +HT+++ +V+ ++ +T+ +GA+++ + A +AI
Sbjct: 453 ISLPDEKGRKDIFLIHTKKLTENGILSSDVNFDELSTLTKNFTGAEIEGLCNSAKSYAIS 512
Query: 363 ER---------------RTYVTQEDFLKAVDKV---LGNERKLLQQITSHEII 397
+ +T++DFL A++ + G + + L Q H II
Sbjct: 513 RHTKKGALAQIDPESIAKMKITRDDFLLALNDIRPAFGTDEEDLSQQAQHGII 565
>sp|P34732|SC18_CANAL VESICULAR-FUSION PROTEIN SEC18 >gi|578124|emb|CAA47077.1| (X66467)
SEC18 [Candida albicans]
Length = 794
Score = 147 bits (368), Expect = 2e-34
Identities = 97/293 (33%), Positives = 158/293 (53%), Gaps = 41/293 (13%)
Query: 142 IGGLKKQLQEL-REAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNA 200
IGGL + Q++ R A + PEL E++ KG+LLYGPPG GKTL+A+ L+ +N
Sbjct: 277 IGGLDAEFQDIFRRAFNSRILPPELAEKLDYKHCKGLLLYGPPGTGKTLIARKLSKMLNG 336
Query: 201 TFIRVV-GSELVRKYIGEGARLVHELFELAKEKAPT--------IIFIDEIDAI----GA 247
++V G E++ KY+G + LF+ A+ + +I DE+D++ G+
Sbjct: 337 KEPKIVNGPEMLSKYVGASEENIRNLFKDAEAEYKLKGEDSDLHVIIFDELDSVFKQRGS 396
Query: 248 KRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIE 307
+ D T G+ VN QLL++MDG D N+ VI TNR D++D ALLRPGRF+ IE
Sbjct: 397 GKSDGTGVGDNVVN----QLLSKMDGVDQLNNILVIGMTNRLDLIDTALLRPGRFEIQIE 452
Query: 308 VPLPDFEGRLEILKVHTRRMK-----LKNVDLRVIAEITEGASGADLKAIATEAGMFAIR 362
+ LPD +GR +I +HT+++ +V+ ++ +T+ +GA+++ + A +AI
Sbjct: 453 ISLPDEKGRKDIFLIHTKKLTENGILSSDVNFDELSTLTKNFTGAEIEGLCNSAKSYAIS 512
Query: 363 ER---------------RTYVTQEDFLKAVDKV---LGNERKLLQQITSHEII 397
+ +T++DFL A++ + G + + L Q H II
Sbjct: 513 RHTKKGALAQIDPESIAKMKITRDDFLLALNDIRPAFGTDEEDLSQQAQHGII 565
>gb|AAF51127.1| (AE003580) CG3326 gene product [Drosophila melanogaster]
Length = 477
Score = 147 bits (368), Expect = 2e-34
Identities = 102/281 (36%), Positives = 151/281 (53%), Gaps = 29/281 (10%)
Query: 139 YNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEV 198
+ DI GL+ EAI +PL+ P+LF V PP+GVLL+GPPG GKTL+AK++A +
Sbjct: 203 WEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRC-PPRGVLLFGPPGTGKTLIAKSIASQA 261
Query: 199 NATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGER 258
A F + S L K++G+ +LV LF +A P IIFIDE+D++ +KR +
Sbjct: 262 KAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKR---SANENE 318
Query: 259 EVNRTLMQLLAEMDGFDPRGNVK--VIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGR 316
R + L +DG ++ VI ATNRP LD A+ R RF R + VPLP E R
Sbjct: 319 STLRLKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREAR 376
Query: 317 LEILKVHTRRMKLKNVDLRVI---AEITEGASGADLKAIATEAGMFAIR----------- 362
+I++ ++K N+D+R + AE+T+G SGAD+ + A M +R
Sbjct: 377 QKIIEKLIHQVK-HNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIE 435
Query: 363 -ERRTYVTQEDF---LKAVDKVLGNERKLLQQITSHEIIYG 399
+ VT +DF L+ + K + +E +Q + IYG
Sbjct: 436 THQLPAVTMDDFKQALRVISKSVSSED--CKQFEAWNEIYG 474
>sp|P54815|MSP1_CAEEL MSP1 PROTEIN HOMOLOG >gi|7505276|pir||T23311 hypothetical protein
K04D7.2 - Caenorhabditis elegans
>gi|3878242|emb|CAA93516.1| (Z69664) Similarity to Yeast
MSP1 protein (TAT-binding homolog 4) (SW:MSP1_YEAST),
contains similarity to Pfam domain: PF00004 (ATPases
associated with various cellular activities (AAA)),
Score=259.1, E-value=2e-74, N=1 [Caenorhabditis elegans]
Length = 357
Score = 142 bits (355), Expect = 6e-33
Identities = 96/263 (36%), Positives = 140/263 (52%), Gaps = 18/263 (6%)
Query: 140 NDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVN 199
N GG ++ + EL++ I LPL+ + PP+G+LLYGPPGCGKTL+AKA+A
Sbjct: 98 NFTGGCEELVAELKDRIILPLRFASQSGSHLLSPPRGILLYGPPGCGKTLLAKAVARAAG 157
Query: 200 ATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGERE 259
FI + S L K+ GE +L +F +A++ PTIIFIDEID+ D +
Sbjct: 158 CRFINLQVSNLTDKWYGESQKLAAAVFSVAQKFQPTIIFIDEIDSF---LRDRQSHDHES 214
Query: 260 VNRTLMQLLAEMDGFDPRGN-VKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLE 318
Q + DGF G+ + V+ ATNRP +D A+LR R +VP+P+ + R +
Sbjct: 215 TAMMKAQFMTLWDGFSSSGDQIIVMGATNRPRDVDAAILR--RMTARFQVPVPNAKQRSQ 272
Query: 319 ILKVHTRRMKLKN-VDLRVIAEITEGASGADLKAI----------ATEAGMFAIRERRTY 367
IL V R K+ N V+L IA+ EG SG+DLK + AT A ++ +
Sbjct: 273 ILNVILRNEKINNTVNLGEIAQAAEGLSGSDLKEVCRLALLARAKATVASGGSVNQLLP- 331
Query: 368 VTQEDFLKAVDKVLGNERKLLQQ 390
+ Q DF AV K + L+++
Sbjct: 332 LEQSDFESAVHKYMRAAHLLVEE 354
>gi|6320887 member of the AAA ATPase family of proteins; Sap1p [Saccharomyces
cerevisiae] >gi|731461|sp|P39955|SAP1_YEAST SAP1 PROTEIN
>gi|1077655|pir||S50550 SIN1-associated protein SAP1 -
yeast (Saccharomyces cerevisiae)
>gi|603280|gb|AAB64582.1| (U18796) Yer047cp
[Saccharomyces cerevisiae]
Length = 897
Score = 140 bits (349), Expect = 3e-32
Identities = 95/281 (33%), Positives = 150/281 (52%), Gaps = 35/281 (12%)
Query: 131 VIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLM 190
V+ V ++DI GL+ L+EA+ P P+LF + +P +G+LL+GPPG GKT++
Sbjct: 596 VVHGDEVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLR-EPVRGMLLFGPPGTGKTML 654
Query: 191 AKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR- 249
A+A+A E ++TF + S L KY+GE +LV LF +AK+ +P+IIF+DEID+I R
Sbjct: 655 ARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIFVDEIDSIMGSRN 714
Query: 250 -MDETTGGEREVNRTLMQLL----------------AEMDGFDPRGNVKVIAATNRPDIL 292
+E R N L+Q ++ +G + V V+AATN P +
Sbjct: 715 NENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSI 774
Query: 293 DPALLRPGRFDRLIEVPLPDFEGRLEILK--VHTRRMKLKNVDLRVIAEITEGASGADLK 350
D A R RF R +PLP+ + R K + ++ L D + +ITEG SG+D+
Sbjct: 775 DEAARR--RFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVKITEGYSGSDIT 832
Query: 351 AIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQI 391
++A +A M +R+ DK+L ER++++ I
Sbjct: 833 SLAKDAAMGPLRD------------LGDKLLETEREMIRPI 861
>pir||T18421 hypothetical protein C0140c - malaria parasite (Plasmodium
falciparum) >gi|3647351|emb|CAB10575.1| (Z97348)
PFC0140c (MAL3P1.10), N-ethylmaleimide-sensitive fusion
protein, len: 783 aa; Similarity to a number of
eukaryotic N-ethylmaleimide sensitive fusion proteins
(NSFs). Human NSF (SW:NSF_MOUSE). BLAST score: 1577, sum
P(2) = 2.4e-142, contains Pf>
Length = 783
Score = 139 bits (347), Expect = 5e-32
Identities = 85/266 (31%), Positives = 147/266 (54%), Gaps = 31/266 (11%)
Query: 165 LFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV-GSELVRKYIGEGARLVH 223
+ +++ I KG++LYGPPG GKTL+A+ + +NA +++ G E++ KY+G+ +
Sbjct: 278 IIKQLSIKHVKGMILYGPPGTGKTLIARQIGKTLNAREPKIINGPEILNKYVGQSEENIR 337
Query: 224 ELFELAKEKAPT--------IIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFD 275
LF+ A+ + II +DEIDAI +R + + + + QLL+++DG +
Sbjct: 338 NLFKDAEMEYKQSGENSLLHIIILDEIDAICRQRGNVGSSSTGVNDSVVNQLLSKIDGVN 397
Query: 276 PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLKN---- 331
N+ +I TNR D++D ALLRPGRF+ IE+ LP+ EGR++IL +HT+ M++ N
Sbjct: 398 SLNNILLIGMTNRIDLIDEALLRPGRFELHIEISLPNKEGRIQILNIHTKNMRMSNKLSS 457
Query: 332 -VDLRVIAEITEGASGADLKAIATEAGMFAIRERRTY-------------VTQEDFLKAV 377
V++ +AE T SGA+++ + +A + +T+ DF+KA+
Sbjct: 458 DVNILELAERTPNFSGAEIEGLVRNTVSYAFERHINFNDLTKPINADDIMITKNDFMKAL 517
Query: 378 DK---VLGNERKLLQQITSHEII-YG 399
+ G E ++ + + II YG
Sbjct: 518 KETKPAFGAEEDIIGNLLCNGIINYG 543
>gb|AAC48226.1| (AF006826) N-ethylmaleimide-sensitive fusion protein [Dictyostelium
discoideum]
Length = 738
Score = 138 bits (344), Expect = 1e-31
Identities = 102/337 (30%), Positives = 168/337 (49%), Gaps = 42/337 (12%)
Query: 99 LRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQEL-REAIE 157
+ P ++ L + ++I++ + P V+ + IGGL + +++ R A
Sbjct: 183 ISPATKIILQKMPGSLIDI--ETNGPLVVNQIFTSDWDFENMGIGGLDAEFRDIFRRAFS 240
Query: 158 LPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVV-GSELVRKYIG 216
+ P + +++G++ KG+LLYGPPG GKTL+A+ + +N +VV G ++ KY+G
Sbjct: 241 SRIFPPAIVKKLGVNHVKGMLLYGPPGTGKTLIARQIGKMLNGREPKVVSGPSILNKYVG 300
Query: 217 EGARLVHELFELAK--------EKAPTIIFIDEIDAI---GAKRMDETTGGEREVNRTLM 265
+ + LF A+ + II DE+DAI R ++ G+ VN
Sbjct: 301 QSEENIRMLFRDAEIEQKAKGDDSGLHIIIFDELDAICKSRGSRQGDSGVGDSVVN---- 356
Query: 266 QLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTR 325
QLLA +DG + N+ VI TNR D++D ALLRPGR + +E+ LPD GR +I K+HT
Sbjct: 357 QLLAMIDGVESLNNILVIGMTNRKDMIDEALLRPGRLEVHVEISLPDEHGREQIFKIHTA 416
Query: 326 RMKLKN-----VDLRVIAEITEGASGADLKAIATEAGMFA--------------IRERRT 366
+M+ +N V+L A T SGA+++ + A +A I+
Sbjct: 417 KMRDQNALDKDVNLANYAHTTRNYSGAEIEGVVKSAASYAFSRQVDTKNIKNVEIKPEDI 476
Query: 367 YVTQEDFLKAVDKV---LGNERKLLQQITSHEII-YG 399
V +DF +A+ +V G+ L+ + II YG
Sbjct: 477 KVCDQDFKRAITEVTPSFGSTDNQLESYAENGIINYG 513
>gi|11466408 hypothetical chloroplast RF2 [Mesostigma viride]
>gi|7259551|gb|AAF43852.1|AF166114_64 (AF166114)
hypothetical chloroplast RF2 [Mesostigma viride]
Length = 890
Score = 133 bits (332), Expect = 3e-30
Identities = 94/288 (32%), Positives = 146/288 (50%), Gaps = 33/288 (11%)
Query: 137 VTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAH 196
+T+ DIGG++ QEL L LK P G L GPPG GKTLMAKA+++
Sbjct: 346 ITFRDIGGMESLKQELATVAFL-LKQKNYSNSY----PMGYLFAGPPGTGKTLMAKAMSY 400
Query: 197 EVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMD----- 251
E ++ V GS+ + G V +LF+ + +P I++IDEID+I +R +
Sbjct: 401 EAETPYLYVEGSQFRCREEGVANARVDDLFKQIQNISPCILYIDEIDSIAERREEANKQL 460
Query: 252 ---ETTG----------GEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLR 298
+T G ++ + LMQ L MDG+ R ++ +I ATNR + LD A++R
Sbjct: 461 EQLKTIGDSIEGSNINIDQKPSDTVLMQFLIYMDGYKKRNDLIIIGATNRIETLDDAIMR 520
Query: 299 PGRFDRLIEVPLPDFEGRLEILKVHTRRMK--LKNVDLRVIAEITEGASGADLKAIATEA 356
PGRFDR I P FE R +IL++ R K + + ++AE + G +G DL+ +A
Sbjct: 521 PGRFDRQIVFSPPFFEERKDILRIFLRNTKALVDDTTKTMMAERSIGLNGCDLRLLADNI 580
Query: 357 GMFAIRERRTY-----VTQEDFLKAVDKVLGNERKLLQQITSHEIIYG 399
+ + E R V ED D+ L ++ I+++E+ +G
Sbjct: 581 LLLSALESRNQQKTIPVINED---TFDRALERVSRIRHIISNYELAFG 625
>gb|AAG28839.1| (U59880) filamentation temperature sensitive H-like protein
[Mycoplasma hominis]
Length = 418
Score = 117 bits (290), Expect = 2e-25
Identities = 62/144 (43%), Positives = 87/144 (60%), Gaps = 1/144 (0%)
Query: 255 GGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFE 314
GG E +TL QLL EMDG + ++AATNR D+LDPALLRPGRFDR I V LPD +
Sbjct: 8 GGNDEREQTLNQLLVEMDGIKENSGILIMAATNRTDVLDPALLRPGRFDRTITVGLPDIK 67
Query: 315 GRLEILKVHTRRMKL-KNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDF 373
R ILK+H ++ N++ ++A T G SGA L+ + EA + ++RE +T E
Sbjct: 68 EREAILKLHANGKRIASNINFAMVARRTPGFSGAQLENVINEASLLSVRENTGVITIEQI 127
Query: 374 LKAVDKVLGNERKLLQQITSHEII 397
+A+D+V+ K + I+ E I
Sbjct: 128 DEAIDRVIAGPAKKSRTISEKENI 151
>pir||JQ1233 hypothetical 41.8K protein - Synechocystis sp
>gi|217104|dbj|BAA00888.1| (D10004) ORF376
[Synechocystis sp.] >gi|243472|gb|AAC60393.1| (S77740)
ORF 376 [Synechocystis, PCC 6803, Peptide, 376 aa]
Length = 376
Score = 106 bits (262), Expect = 5e-22
Identities = 89/310 (28%), Positives = 141/310 (44%), Gaps = 23/310 (7%)
Query: 95 ERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE--RPNVTYNDIGGL---KKQL 149
E +K+ A V Q T +E++ S K + +++ + T +GGL KK L
Sbjct: 62 EAEKVYRKAYVKAGQLTEGEVEIVLSEKKQLIRRNGILDYIEEDETIRAVGGLEELKKWL 121
Query: 150 QELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRV-VGS 208
+ +A E E G+ PKG+L+ G PGCGK+L+AK + +R+ +G
Sbjct: 122 TQRSDAFT------ERAREYGLPQPKGMLILGVPGCGKSLIAKTTSRLWGLPLLRLDMGR 175
Query: 209 ELVRKYIGEGARLVHELFELAKEKAPTIIFIDEID---AIGAKRMDETTGGEREVNRTLM 265
+G + + A+ +P I+FIDE+D A GA D G + + +
Sbjct: 176 VYDGSMVGRSEANLRNALKTAESISPAILFIDELDKAFAGGAGSGDSDGGTSSRIFGSFL 235
Query: 266 QLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKV--H 323
+ E V V+A NR D L LR GRFD + V LP E R I ++ H
Sbjct: 236 TWMQE-----KTSPVFVMATANRVDRLPGEFLRKGRFDEIFFVDLPSSEEREAIFRIHLH 290
Query: 324 TRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGN 383
RR DL +A ++G SGA+++ A A + R + Q D + A+ L
Sbjct: 291 KRRKDTSRFDLGELARTSDGFSGAEIEQAIVAAMYEAFAQEREF-NQLDIIAAIKSTLPL 349
Query: 384 ERKLLQQITS 393
R +++Q+T+
Sbjct: 350 SRTMVEQVTA 359
>pir||S76117 hypothetical protein slr0374 - Synechocystis sp. (strain PCC 6803)
>gi|1001469|dbj|BAA10095.1| (D63999) cell division cycle
protein [Synechocystis sp.]
Length = 501
Score = 106 bits (262), Expect = 5e-22
Identities = 89/310 (28%), Positives = 141/310 (44%), Gaps = 23/310 (7%)
Query: 95 ERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIE--RPNVTYNDIGGL---KKQL 149
E +K+ A V Q T +E++ S K + +++ + T +GGL KK L
Sbjct: 180 EAEKVYRKAYVKAGQLTEGEVEIVLSEKKQLIRRNGILDYIEEDETIRAVGGLEELKKWL 239
Query: 150 QELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRV-VGS 208
+ +A E E G+ PKG+L+ G PGCGK+L+AK + +R+ +G
Sbjct: 240 TQRSDAFT------ERAREYGLPQPKGMLILGVPGCGKSLIAKTTSRLWGLPLLRLDMGR 293
Query: 209 ELVRKYIGEGARLVHELFELAKEKAPTIIFIDEID---AIGAKRMDETTGGEREVNRTLM 265
+G + + A+ +P I+FIDE+D A GA D G + + +
Sbjct: 294 VYDGSMVGRSEANLRNALKTAESISPAILFIDELDKAFAGGAGSGDSDGGTSSRIFGSFL 353
Query: 266 QLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKV--H 323
+ E V V+A NR D L LR GRFD + V LP E R I ++ H
Sbjct: 354 TWMQE-----KTSPVFVMATANRVDRLPGEFLRKGRFDEIFFVDLPSSEEREAIFRIHLH 408
Query: 324 TRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGN 383
RR DL +A ++G SGA+++ A A + R + Q D + A+ L
Sbjct: 409 KRRKDTSRFDLGELARTSDGFSGAEIEQAIVAAMYEAFAQEREF-NQLDIIAAIKSTLPL 467
Query: 384 ERKLLQQITS 393
R +++Q+T+
Sbjct: 468 SRTMVEQVTA 477
>pir||S74396 hypothetical protein slr0480 - Synechocystis sp. (strain PCC 6803)
>gi|1001171|dbj|BAA10314.1| (D64001) hypothetical
protein [Synechocystis sp.]
Length = 499
Score = 103 bits (254), Expect = 4e-21
Identities = 87/287 (30%), Positives = 131/287 (45%), Gaps = 23/287 (8%)
Query: 115 IELLPSSKDPTVLGFEVIE--RPNVTYNDIGGLKKQLQELREAIELPLKHPELFEE---- 168
+EL+ K ++ ++++ + +DIGGL L L+ F E
Sbjct: 201 VELMLEEKRQSIRQTQILDFYPASERISDIGGLDNLKDWL-------LRRGGAFSEQARR 253
Query: 169 VGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFEL 228
G+ P+G+LL G G GK+L AKA+AH + +R+ L +GE ++ L
Sbjct: 254 YGLPYPRGLLLAGIQGTGKSLTAKAIAHHWHLPLLRLDVGRLFGGLVGESEARTRQMINL 313
Query: 229 AKEKAPTIIFIDEID-AIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATN 287
A+ AP + +IDEID A G+ G V + LAE V V+A N
Sbjct: 314 AEALAPCVFWIDEIDKAFGSMDSHGDGGTTSRVFGAFITWLAE-----KTSPVFVVATAN 368
Query: 288 RPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRM---KLKNVDLRVIAEITEGA 344
L P LLR GRFD + V LP+ R I VH R+ K+ + D+ +A T
Sbjct: 369 NVQSLPPELLRKGRFDEIFFVGLPNKTEREAIFSVHLNRLRPHKMADYDIHRLAYETPDF 428
Query: 345 SGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQI 391
SGA+++ I EA + R + T +D L A +V+ R +QI
Sbjct: 429 SGAEIEQILVEAMHIGFSQNREFTT-DDILSAASQVVPLARTAKEQI 474
>gb|AAB05472.1| (U59625) unknown [Helicobacter pylori]
Length = 309
Score = 87.8 bits (214), Expect = 2e-16
Identities = 47/104 (45%), Positives = 68/104 (65%), Gaps = 1/104 (0%)
Query: 293 DPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLKN-VDLRVIAEITEGASGADLKA 351
DPAL+RPGRFDR + V PDF GR+EILKVH + +KL N V+L+ +A++T G +GADL
Sbjct: 1 DPALMRPGRFDRQVLVDKPDFNGRVEILKVHIKGVKLANDVNLQEVAKLTAGLAGADLAN 60
Query: 352 IATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHE 395
I EA + A R + V Q+ +AV++ + K ++I+ E
Sbjct: 61 IINEAALLAGRNNQKEVRQQHLKEAVERGIAGLEKKSRRISPKE 104
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.141 0.394
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 144425659
Number of Sequences: 2977
Number of extensions: 6147063
Number of successful extensions: 27794
Number of sequences better than 1.0e-10: 518
Number of HSP's better than 0.0 without gapping: 464
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 26071
Number of HSP's gapped (non-prelim): 689
length of query: 399
length of database: 189,106,746
effective HSP length: 57
effective length of query: 342
effective length of database: 154,992,987
effective search space: 53007601554
effective search space used: 53007601554
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)