BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2265 (orc1) DE:cell division control protein 6, putative
(432 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75199 probable cell division control protein 6 PAB2265 - P... 854 0.0
pir||B71233 hypothetical protein PH0124 - Pyrococcus horikoshii ... 814 0.0
pir||T43932 cell division control protein 6 homolog [imported] -... 785 0.0
gi|11497860 cell division control protein 6, putative [Archaeogl... 467 e-131
gb|AAK40596.1| Cell division control 6/orc1 protein homolog (cd... 384 e-105
pir||D72743 probable DNA polymerase II APE0475 - Aeropyrum perni... 352 4e-96
gb|AAG20498.1| (AE005122) orc / cell division control protein 6;... 352 4e-96
emb|CAC11775.1| (AL445064) probable DNA polymerase II (DP2), sub... 326 4e-88
pir||B69055 probable cell division control protein 6 - Methanoba... 285 8e-76
gb|AAG18684.1| (AE004973) Vng0045c [Halobacterium sp. NRC-1] 261 1e-68
gb|AAG20983.1| (AE005165) orc / cell division control protein 6;... 248 1e-64
gb|AAG19588.1| (AE005048) orc / cell division control protein 6;... 236 5e-61
gi|10954477 ORF1 [Methanobacterium thermoautotrophicum] >gi|2675... 206 3e-52
gi|10954475 orf1 [Methanobacterium thermoautotrophicum] >gi|2675... 205 6e-52
gb|AAG20915.1| (AE005158) orc / cell division control protein 6;... 202 6e-51
gb|AAK42358.1| Cell division control 6/orc1 protein homolog (cd... 200 3e-50
gb|AAK41068.1| Cell division control 6/orc1 protein homolog (cd... 168 1e-40
emb|CAB57532.1| (Y18930) cell division control 6 (cdc6) protein ... 168 1e-40
pir||D69080 Cdc6 related protein - Methanobacterium thermoautotr... 159 8e-38
gb|AAG20387.1| (AE005112) orc / cell division control protein 6;... 148 1e-34
gi|11498302 conserved hypothetical protein [Archaeoglobus fulgid... 132 9e-30
gb|AAG20835.1| (AE005152) orc / cell division control protein 6;... 126 4e-28
gi|10803617 ORF H0761 [Halobacterium sp. NRC-1] >gi|7484055|pir|... 123 4e-27
pdb|1FNN|A Chain A, Crystal Structure Of Cdc6p From Pyrobaculum ... 119 5e-26
gi|4502703 CDC6 (cell division cycle 6, S. cerevisiae) homolog; ... 113 3e-24
gi|6753368 cell division cycle 6 homolog (S. cerevisiae); CDC18(... 111 1e-23
pir||E72770 hypothetical protein APE0152 - Aeropyrum pernix (str... 109 6e-23
gb|AAF50387.1| (AE003554) CG5971 gene product [Drosophila melano... 109 8e-23
pir||T26734 hypothetical protein Y39A1A.12 - Caenorhabditis eleg... 104 2e-21
gb|AAG20823.1| (AE005151) orc / cell division control protein 6;... 102 6e-21
gb|AAC69366.1| (U76834) Cdc6-related protein [Xenopus laevis] 101 1e-20
pir||T46977 cell division control protein 6 [validated] - Africa... 99 1e-19
emb|CAB53755.1| (AL049730) origin recognition complex subunit 1-... 99 1e-19
pir||G71409 probable replication control protein - Arabidopsis t... 97 4e-19
sp|P54789|ORC1_SCHPO ORIGIN RECOGNITION COMPLEX SUBUNIT 1 >gi|74... 96 7e-19
gb|AAB38247.1| (U43392) origin recognition protein Orc1+p [Schiz... 96 7e-19
gb|AAF66067.1|AF254572_1 (AF254572) origin recognition complex s... 95 1e-18
gb|AAC60033.1| (U67190) origin recognition complex protein 1 [Xe... 92 1e-17
sp|O16810|ORC1_DROME ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (DMORC... 91 2e-17
gb|AAF59236.1| (AE003840) Orc1 gene product [Drosophila melanoga... 91 2e-17
sp|P41411|CC18_SCHPO CELL DIVISION CONTROL PROTEIN 18 >gi|539072... 90 4e-17
gi|4758850 origin recognition complex, subunit 1 (yeast homolog)... 88 2e-16
pir||G02329 replication control protein 1 - human >gi|1171204|gb... 88 2e-16
gi|11422006 origin recognition complex, subunit 1 (yeast homolog... 87 3e-16
gi|6754944 origin recognition complex, subunit 1 homolog (S. cer... 87 4e-16
emb|CAC11593.1| (AL445064) cell division control protein 6 relat... 85 2e-15
dbj|BAA89785.1| (AB037135) origin recognition complex 1 [Oryza s... 83 7e-15
pir||T46606 cell cycle control protein cdc6 [imported] - yeast (... 80 4e-14
gb|AAB37629.1| (U80437) similar to several cell division control... 78 2e-13
gi|10803686 ORF H1602 [Halobacterium sp. NRC-1] >gi|7484016|pir|... 78 2e-13
gb|AAC35241.1| (AC005496) putative CDC6 protein [Arabidopsis tha... 77 4e-13
>pir||G75199 probable cell division control protein 6 PAB2265 - Pyrococcus
abyssi (strain Orsay) >gi|5457555|emb|CAB49046.1|
(AJ248283) cell division control protein 6, putative
[Pyrococcus abyssi]
Length = 432
Score = 854 bits (2182), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MSFKSTISTGGTSMSEGEQLHLDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEA 60
MSFKSTISTGGTSMSEGEQLHLDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEA
Sbjct: 1 MSFKSTISTGGTSMSEGEQLHLDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEA 60
Query: 61 LAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVD 120
LAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVD
Sbjct: 61 LAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVD 120
Query: 121 THYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKS 180
THYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKS
Sbjct: 121 THYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKS 180
Query: 181 GDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKD 240
GDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKD
Sbjct: 181 GDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKD 240
Query: 241 ILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKH 300
ILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKH
Sbjct: 241 ILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKH 300
Query: 301 VWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDL 360
VWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDL
Sbjct: 301 VWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDL 360
Query: 361 EPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLL 420
EPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLL
Sbjct: 361 EPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLL 420
Query: 421 TVSLKGGQRRLL 432
TVSLKGGQRRLL
Sbjct: 421 TVSLKGGQRRLL 432
>pir||B71233 hypothetical protein PH0124 - Pyrococcus horikoshii
>gi|3256510|dbj|BAA29193.1| (AP000001) 437aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 437
Score = 814 bits (2079), Expect = 0.0
Identities = 406/430 (94%), Positives = 421/430 (97%)
Query: 3 FKSTISTGGTSMSEGEQLHLDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALA 62
FKS +S+GGTSM+EGEQLHLD+LFE+LLKARKIFKNKEVLRHSYTPKDLPHRHEQIE LA
Sbjct: 8 FKSIVSSGGTSMNEGEQLHLDQLFEKLLKARKIFKNKEVLRHSYTPKDLPHRHEQIETLA 67
Query: 63 QILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTH 122
QILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVS KYNIPV+VIYINCEIVDTH
Sbjct: 68 QILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSHKYNIPVDVIYINCEIVDTH 127
Query: 123 YRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGD 182
YRVLANIVNHFK ETGIEVPLVGWPTDEVYAKLKQVIDM+ERFVIIVLDEIDKLVKKSGD
Sbjct: 128 YRVLANIVNHFKHETGIEVPLVGWPTDEVYAKLKQVIDMRERFVIIVLDEIDKLVKKSGD 187
Query: 183 EVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDIL 242
EVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQL+DIL
Sbjct: 188 EVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLRDIL 247
Query: 243 TQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVW 302
QRAEEAFYPGVL++GVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVW
Sbjct: 248 MQRAEEAFYPGVLDDGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVW 307
Query: 303 RAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEP 362
+AQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENG+LPANTGEVYSVYR+LCEYLDLEP
Sbjct: 308 KAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGELPANTGEVYSVYRDLCEYLDLEP 367
Query: 363 LTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLLTV 422
LTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDY IQPLL +
Sbjct: 368 LTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYTIQPLLAI 427
Query: 423 SLKGGQRRLL 432
SLK QRRL+
Sbjct: 428 SLKDSQRRLV 437
>pir||T43932 cell division control protein 6 homolog [imported] - Pyrococcus
furiosus >gi|2967435|dbj|BAA25162.1| (D84670) ORF1
[Pyrococcus furiosus]
Length = 420
Score = 785 bits (2004), Expect = 0.0
Identities = 391/420 (93%), Positives = 413/420 (98%), Gaps = 1/420 (0%)
Query: 14 MSEGE-QLHLDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGE 72
M+EGE Q+ LD+LFE+LL+ARKIFKNK+VLRHSYTPKDLPHRHEQIE LAQILVPVL+GE
Sbjct: 1 MNEGEHQIKLDELFEKLLRARKIFKNKDVLRHSYTPKDLPHRHEQIETLAQILVPVLRGE 60
Query: 73 TPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNH 132
TPSNIFVYGKTGTGKTVTVKFVTEELK++S+KYNIPV+VIYINCEIVDTHYRVLANIVN+
Sbjct: 61 TPSNIFVYGKTGTGKTVTVKFVTEELKRISEKYNIPVDVIYINCEIVDTHYRVLANIVNY 120
Query: 133 FKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRIN 192
FKDETGIEVP+VGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRIN
Sbjct: 121 FKDETGIEVPMVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRIN 180
Query: 193 TELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYP 252
TELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQL+DILTQRAEEAFYP
Sbjct: 181 TELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLRDILTQRAEEAFYP 240
Query: 253 GVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDM 312
GVL+EGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVW+AQEKIEQDM
Sbjct: 241 GVLDEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWKAQEKIEQDM 300
Query: 313 MEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLI 372
MEEVIKTLPLQSKVLLYAIVLLDENGDLPANTG+VY+VYRELCEY+DLEPLTQRRISDLI
Sbjct: 301 MEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGDVYAVYRELCEYIDLEPLTQRRISDLI 360
Query: 373 NELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLLTVSLKGGQRRLL 432
NELDMLGIINAKVVSKGRYGRTKEIRLNVT YKIRNV RYDY+IQPLLT+SLK QRRL+
Sbjct: 361 NELDMLGIINAKVVSKGRYGRTKEIRLNVTSYKIRNVLRYDYSIQPLLTISLKSEQRRLI 420
>gi|11497860 cell division control protein 6, putative [Archaeoglobus fulgidus]
>gi|7429754|pir||D69280 cell division control protein 6
homolog - Archaeoglobus fulgidus
>gi|2650397|gb|AAB90989.1| (AE001089) cell division
control protein 6, putative [Archaeoglobus fulgidus]
Length = 409
Score = 467 bits (1190), Expect = e-131
Identities = 234/395 (59%), Positives = 304/395 (76%), Gaps = 6/395 (1%)
Query: 25 LFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTG 84
+F+ +L + IFKN++VLRHSYTP+ LPHR EQI LA +L P+L+G TPSNIF+YGKTG
Sbjct: 3 IFDNILSSATIFKNRDVLRHSYTPEKLPHREEQINQLALLLSPMLRGGTPSNIFIYGKTG 62
Query: 85 TGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLV 144
TGKT TV FV +L++ S+K + V V YINCEIVDT YRVLA++ F G VP+
Sbjct: 63 TGKTATVLFVARQLEEASRKAKLNVAVHYINCEIVDTAYRVLASLARKF----GSNVPMT 118
Query: 145 GWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIG 204
GWPTD+VY ++K+ ++ + V+++LDEIDKLVKK+ +E LY LTRIN+EL+ + + ++G
Sbjct: 119 GWPTDQVYEEVKKALERRGTRVVVILDEIDKLVKKA-EEALYGLTRINSELENSSICIVG 177
Query: 205 ISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCA 264
ISN+LKFKEYLD R+LSSLSEEE+VFPPY+A QL+DIL QRA+ AF GVLE+GVI LCA
Sbjct: 178 ISNNLKFKEYLDARILSSLSEEEIVFPPYNAEQLEDILQQRAKLAFEDGVLEDGVIQLCA 237
Query: 265 ALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQS 324
A+AA+EHGDARKALDLLRV+ EIAERE S V +HV +A KIE D M E ++TLP+ S
Sbjct: 238 AIAAQEHGDARKALDLLRVSAEIAERERDSMVRVEHVKKAVRKIETDYMIETVRTLPVHS 297
Query: 325 KVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAK 384
K+LLY++ L+ EN TGEVY VY++LC + ++PLTQRRISDLI+ELDMLGI+N+
Sbjct: 298 KILLYSMSLISENSP-KFTTGEVYCVYKKLCGKVGVDPLTQRRISDLISELDMLGILNSV 356
Query: 385 VVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPL 419
V+SKGRYGRT+E++L +R DY +Q L
Sbjct: 357 VISKGRYGRTREMKLEADEKVLRKALEEDYRLQNL 391
>gb|AAK40596.1| Cell division control 6/orc1 protein homolog (cdc6-1) [Sulfolobus
solfataricus]
Length = 397
Score = 384 bits (976), Expect = e-105
Identities = 195/371 (52%), Positives = 269/371 (71%), Gaps = 7/371 (1%)
Query: 31 KARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVT 90
K IF N+E L Y P +LPHR +QI +A IL P+ + E P+NIF+YG TGTGKT
Sbjct: 13 KTSSIFINREYLLPDYIPDELPHREDQIRKIASILAPLYREEKPNNIFIYGLTGTGKTAV 72
Query: 91 VKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDE 150
VKFV L K+ +K+ + +YIN +DT YRVLA+++ + ++VP G E
Sbjct: 73 VKFV---LSKLHKKFLGKFKHVYINTRQIDTPYRVLADLL----ESLDVKVPFTGLSIAE 125
Query: 151 VYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLK 210
+Y +L + + V+IVLDEID VKK D++LY L+RIN+E+ ++K+S IGI+ND+K
Sbjct: 126 LYRRLVKAVRDYGSQVVIVLDEIDAFVKKYNDDILYKLSRINSEVNKSKISFIGITNDVK 185
Query: 211 FKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAARE 270
F + LDPRV SSLSEEE++FPPY+A +L+DILT+RA+ AF PGVL + VI LCAALAARE
Sbjct: 186 FVDLLDPRVKSSLSEEEIIFPPYNAEELEDILTKRAQMAFKPGVLPDNVIKLCAALAARE 245
Query: 271 HGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYA 330
HGDAR+ALDLLRV+GEIAER +KV E++V+ A+E+IE+D + ++I TLP SK++L A
Sbjct: 246 HGDARRALDLLRVSGEIAERMKDTKVKEEYVYMAKEEIERDRVRDIILTLPFHSKLVLMA 305
Query: 331 IVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGR 390
+V + ++ + TG VY Y +C+ L +E +TQRR+SD+INELDM+GI+ AKVV++GR
Sbjct: 306 VVSISSEENVVSTTGAVYETYLNICKKLGVEAVTQRRVSDIINELDMVGILTAKVVNRGR 365
Query: 391 YGRTKEIRLNV 401
YG+TKEI L V
Sbjct: 366 YGKTKEIGLAV 376
>pir||D72743 probable DNA polymerase II APE0475 - Aeropyrum pernix (strain K1)
>gi|5104124|dbj|BAA79440.1| (AP000059) 377aa long
hypothetical DNA polymerase II [Aeropyrum pernix]
Length = 377
Score = 352 bits (894), Expect = 4e-96
Identities = 189/382 (49%), Positives = 255/382 (66%), Gaps = 7/382 (1%)
Query: 41 VLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKK 100
+L Y P LPHR ++ LA++L P L+GE PSN +YG TGTGKT + V L+
Sbjct: 1 MLLPDYVPDVLPHREAELRRLAEVLAPALRGEKPSNALLYGLTGTGKTAVARLVLRRLEA 60
Query: 101 VSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVID 160
+ + V+ IY+N +T YRV + I + G+ VP G EVY +L + +
Sbjct: 61 RASSLGVLVKPIYVNARHRETPYRVASAIA----EAVGVRVPFTGLSVGEVYERLVKRLS 116
Query: 161 MKERFVIIVLDEIDKLVKK-SGDEVLYSLTRINTEL-KRAKVSVIGISNDLKFKEYLDPR 218
IIVLDEID L K+ G ++LY +TRIN EL R VS++GI+N L F E L+PR
Sbjct: 117 RLRGIYIIVLDEIDFLPKRPGGQDLLYRITRINQELGDRVWVSLVGITNSLGFVENLEPR 176
Query: 219 VLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKAL 278
V SSL E E+VFPPY A QL+DIL RAEEAF PGVL+ V+PLCAALAAREHGDAR+AL
Sbjct: 177 VKSSLGEVELVFPPYTAPQLRDILETRAEEAFNPGVLDPDVVPLCAALAAREHGDARRAL 236
Query: 279 DLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENG 338
DLLRVAGEIAER +V +HV+ A+ +IE+D + EV++TLPL +K++L +I++L E+G
Sbjct: 237 DLLRVAGEIAERRREERVRREHVYSARAEIERDRVSEVVRTLPLHAKLVLLSIMML-EDG 295
Query: 339 DLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIR 398
PA+TGE+Y Y+EL L LE +T RR+S +I+ELDMLGI+ ++VVS+GRYG+T+E+
Sbjct: 296 GRPASTGEIYERYKELTSTLGLEHVTLRRVSGIISELDMLGIVKSRVVSRGRYGKTREVS 355
Query: 399 LNVTPYKIRNVFRYDYAIQPLL 420
L+ + N D + LL
Sbjct: 356 LDADRLAVENALSEDPFVARLL 377
>gb|AAG20498.1| (AE005122) orc / cell division control protein 6; Orc7
[Halobacterium sp. NRC-1]
Length = 518
Score = 352 bits (894), Expect = 4e-96
Identities = 172/274 (62%), Positives = 218/274 (78%)
Query: 140 EVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAK 199
+VP+ GWPTD VYA +D ER +I+LDEIDKLV+KSGD+ LY+L+R+N+EL ++
Sbjct: 225 QVPMTGWPTDRVYATFFDAVDYVERVAVIMLDEIDKLVEKSGDDTLYNLSRMNSELDNSR 284
Query: 200 VSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGV 259
VS+IGISNDLKF ++LDPRV SSL EEE+VFPPYDANQL+DIL R++ AF L + V
Sbjct: 285 VSIIGISNDLKFTDFLDPRVKSSLGEEEIVFPPYDANQLRDILQHRSDVAFKADALSDDV 344
Query: 260 IPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKT 319
+PLCAA AA+EHGDAR+ALDLLR AGE+AER+ A VTE HV RAQ+KIE D + EV++T
Sbjct: 345 LPLCAAFAAQEHGDARRALDLLRTAGELAERDQAENVTEDHVRRAQDKIELDRVVEVVRT 404
Query: 320 LPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLG 379
LP QSK++LYAI+LL++NG NTGEVY++Y+ LC+ LD + LTQRR++DLI+ELDMLG
Sbjct: 405 LPTQSKLVLYAILLLEDNGVHNVNTGEVYNIYKTLCDELDADVLTQRRVTDLISELDMLG 464
Query: 380 IINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYD 413
I+NA VVSKGRYGRTKEI L+V + V D
Sbjct: 465 IVNAVVVSKGRYGRTKEISLSVPVEETEAVLEAD 498
Score = 151 bits (378), Expect = 1e-35
Identities = 70/112 (62%), Positives = 88/112 (78%)
Query: 25 LFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTG 84
LF+ LL IF+NKEVLR SYTP +LPHR++QI +A ILV L+GETPSNI +YGKTG
Sbjct: 34 LFDDLLSGEPIFENKEVLRPSYTPHELPHRNDQINNMATILVAALRGETPSNILIYGKTG 93
Query: 85 TGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDE 136
TGKT + KFV++EL+K S+KY++P EV YINCE+ DT YRVLA + N F D+
Sbjct: 94 TGKTASAKFVSQELEKTSKKYDVPCEVEYINCEVTDTQYRVLAQLANTFIDQ 145
>emb|CAC11775.1| (AL445064) probable DNA polymerase II (DP2), subunit 1
[Thermoplasma acidophilum]
Length = 404
Score = 326 bits (826), Expect = 4e-88
Identities = 159/374 (42%), Positives = 242/374 (64%), Gaps = 7/374 (1%)
Query: 22 LDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYG 81
+D F R R I N +L +Y P PHR QI + IL +++G PSNI VYG
Sbjct: 1 MDNPFARFAGTRTIQANLSLLEENYVPDSFPHRENQINEMVTILSSIMRGSRPSNIIVYG 60
Query: 82 KTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEV 141
KTGTGKT T K+VT+ L + + V V+Y+NCEI D+ Y +L I N +E ++
Sbjct: 61 KTGTGKTSTTKYVTKMLVEAASN----VSVVYVNCEIYDSPYSILVAIANSAGEE---KI 113
Query: 142 PLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVS 201
P +GWP D +Y + + ++ +F II+LDE+D+L+KK+G + LY L ++ T++ +VS
Sbjct: 114 PELGWPIDRIYRETVERVEKTGKFFIIILDEMDRLIKKNGGDSLYVLLKLMTDVDSVRVS 173
Query: 202 VIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIP 261
+IGI+ND E +D R+ S L++E +VFPPY+A++++DI++ R ++ PGV+++ I
Sbjct: 174 MIGITNDTTVLENIDARIKSRLNQESIVFPPYNASEIRDIISSRLDKVLGPGVVDDTAIN 233
Query: 262 LCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLP 321
LCAA+ A+EHGDARKA+DL+R+A EIA RE +K+TE ++ A+E+ E +++ E I TLP
Sbjct: 234 LCAAIGAQEHGDARKAIDLMRIAIEIAIRENRNKITENEIYEARERYEMNVLREAISTLP 293
Query: 322 LQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGII 381
L SK++L + V+ E TGE+Y YR +C+ L PL+ RRISDL+ EL G++
Sbjct: 294 LHSKIVLLSAVVTQEIEPNSVITGEIYENYRRICDDLGFSPLSPRRISDLLTELADYGLL 353
Query: 382 NAKVVSKGRYGRTK 395
+ G+YGRT+
Sbjct: 354 VMDDRNMGKYGRTR 367
>pir||B69055 probable cell division control protein 6 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622524|gb|AAB85889.1| (AE000903) Cdc6 related
protein [Methanobacterium thermoautotrophicum]
Length = 382
Score = 285 bits (721), Expect = 8e-76
Identities = 158/380 (41%), Positives = 236/380 (61%), Gaps = 19/380 (5%)
Query: 25 LFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTG 84
+F+ + +FK+K+ L H + P LPHR EQI ++A+ V L G TP +I +YGKTG
Sbjct: 3 IFDEIGDKESVFKDKKYLDHRFLPDRLPHREEQIRSIAKYWVEALNGVTPPDITIYGKTG 62
Query: 85 TGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLV 144
TGKT KF ++LK+ S+ ++ + YI C T Y+V+A + + G +VP
Sbjct: 63 TGKTAVAKFAMKQLKEASKDCDVNIRTEYIRCTDYTTEYQVIARLCQ----QLGRDVPYR 118
Query: 145 GWPTDEVYAKLKQVIDM----KERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKV 200
GW E+ + + ++ +++VLDEID L++ GD +LY+LTR + V
Sbjct: 119 GWTKAEIVNTFRNMFKKNAFGQDMILMVVLDEIDILLRNDGDGLLYTLTRTDN------V 172
Query: 201 SVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVI 260
S++ ISN ++FK+++ PRV SSL + E+VFPPY A QL DIL +R++ +F G L++ VI
Sbjct: 173 SILSISNYVEFKKFIKPRVRSSLRDREIVFPPYGAQQLVDILEERSKMSFKEGALDDDVI 232
Query: 261 PLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTL 320
PLCAALAA+E GDAR ALDLLR AGEIA+ + KV V A++ IE + + ++I TL
Sbjct: 233 PLCAALAAKEEGDARYALDLLRTAGEIADERDSDKVLGDFVREAKDYIEHNKITDIILTL 292
Query: 321 PLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGI 380
P Q + +L AI+ L + + +G +Y VY+E+ + + ++ RRI D INEL+MLG+
Sbjct: 293 PSQQQRVLEAILYLTKRKE-EITSGRLYEVYKEIAKG---DSVSYRRIFDFINELEMLGL 348
Query: 381 INAKVVSKGR-YGRTKEIRL 399
I+ VS+GR GRT I L
Sbjct: 349 ISTNTVSRGRGKGRTNIIDL 368
>gb|AAG18684.1| (AE004973) Vng0045c [Halobacterium sp. NRC-1]
Length = 471
Score = 261 bits (659), Expect = 1e-68
Identities = 152/402 (37%), Positives = 230/402 (56%), Gaps = 14/402 (3%)
Query: 11 GTSMSEGEQLHLDKLFERLL------KARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQI 64
G S++ GE + L LL + + IF NK+ L SY P + R ++IE
Sbjct: 41 GCSLASGETVVLLSSLGVLLSMPSFERKQNIFANKDALGESYQPNKIEERDDEIEKYMDA 100
Query: 65 LVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYN-IPVEVIYINCEIVDTHY 123
L PV+ G P+NIFVYG TG GKT + ++L+ + Y+ + + VIY+NC+ + + Y
Sbjct: 101 LQPVIDGWEPNNIFVYGNTGVGKTAVTDHLLDQLQTDVEAYDDVTLSVIYLNCKTLSSSY 160
Query: 124 RVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDE 183
+V +VN + G E+ G+P V+ KL Q ++ ++IVLDE+D + + D+
Sbjct: 161 QVAVELVNKLR-RPGAEISSTGYPQQSVFKKLYQELEALGGTILIVLDEVDAIGDR--DD 217
Query: 184 VLYSLTRINTE--LKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDI 241
+LY L R ++ L+ AKV +IGISND KF+E LDPRV +L E E+ FPPYDA +L +I
Sbjct: 218 LLYELPRARSQGNLEDAKVGIIGISNDYKFQEQLDPRVQDTLCERELQFPPYDALELANI 277
Query: 242 LTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHV 301
L R + A L EGV CAALAAR+ G AR+ALDLLR+AGE+AE + A ++ HV
Sbjct: 278 LDSRTDIAIADDSLAEGVTQHCAALAARDSGSARQALDLLRLAGELAENQDADAISTDHV 337
Query: 302 WRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYL--D 359
A+ ++E++ +EE ++ L ++ L A+V D P+ T +Y Y LC+
Sbjct: 338 EAARSELERERVEEGMRELTTHGRLTLLAVVSKAAKADTPSRTRAIYDEYASLCKSAANT 397
Query: 360 LEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNV 401
+PL QR + + +++L MLGI++ G G L+V
Sbjct: 398 DDPLKQRSVHNHLSDLHMLGILSKYENRSGSRGNYYSYELDV 439
>gb|AAG20983.1| (AE005165) orc / cell division control protein 6; Orc4
[Halobacterium sp. NRC-1]
Length = 410
Score = 248 bits (626), Expect = 1e-64
Identities = 148/376 (39%), Positives = 220/376 (58%), Gaps = 14/376 (3%)
Query: 23 DKLFERLLKARKIFKNKEVLRHSYTPKD--LPHRHEQIEALAQILVPVLKGETPSNIFVY 80
D LFE +IF NK++L+ + P+ + R E+I LA+ L + G +P N+ +Y
Sbjct: 12 DPLFE---SGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGYSPENVMIY 68
Query: 81 GKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDE--TG 138
GKTGTGK++ K V + + +Q + + YI+C +T + ++++ DE TG
Sbjct: 69 GKTGTGKSLVSKHVCQRAQNAAQD-GVEIGTAYIDCAEDNTETQAISSLAAKLNDESSTG 127
Query: 139 IEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELK-R 197
I VP G T + Y L + +D + VII+LDEID + + D VL L+R K
Sbjct: 128 ISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILDEIDLM---NDDSVLMKLSRAEEAGKID 184
Query: 198 AKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEE 257
V VI ISN +++ + ++ RV SS +E+ F PYDANQL++I+ R E+AF GVL E
Sbjct: 185 CSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNR-EDAFQDGVLSE 243
Query: 258 GVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVI 317
VIPL AA AA+EHGDARKA+D+LR AGE+A GA VTE+HV +AQ+ E+D E++
Sbjct: 244 DVIPLSAAFAAQEHGDARKAIDILRHAGEVAYEAGAELVTEEHVRQAQQHAEKDRFRELV 303
Query: 318 KTLPLQSKVLLYAIVLLDENGDLPA-NTGEVYSVYRELCEYLDLEPLTQRRISDLINELD 376
P Q+K L A+ L N + A T VY Y +C +LD++ L+ RR D++ E
Sbjct: 304 NGAPTQAKAALLALTELSVNSNDDAFLTSRVYDQYEHICNHLDMDILSVRRFRDILKEQA 363
Query: 377 MLGIINAKVVSKGRYG 392
LG++ + ++KG G
Sbjct: 364 FLGVVEIEKINKGSAG 379
>gb|AAG19588.1| (AE005048) orc / cell division control protein 6; Orc8
[Halobacterium sp. NRC-1]
Length = 397
Score = 236 bits (595), Expect = 5e-61
Identities = 136/363 (37%), Positives = 203/363 (55%), Gaps = 6/363 (1%)
Query: 34 KIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKF 93
++F NK+VL+ Y P+++ R E+I+ A L V+ G P N+FVYGKTG GKT ++
Sbjct: 10 ELFANKDVLKDHYEPEEIRERDEEIDQYANALQDVVDGWEPDNVFVYGKTGVGKTAVTRY 69
Query: 94 VTEELKKVSQKYN--IPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEV 151
+ + L+ + + V + +NC + Y+ +VN + +T + G T +V
Sbjct: 70 MMDALEYEADDRDGVDSVTSVEVNCHHHPSSYQAAIALVNELRGDTDSDPLTTGLSTSDV 129
Query: 152 YAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTE--LKRAKVSVIGISNDL 209
L I+ +E V+IVLDEID L D +LY L R T ++ ++V+V+GISND
Sbjct: 130 LNALFDEIEAREGTVLIVLDEIDNL--DDDDMLLYQLPRAKTNGNIEDSQVAVVGISNDY 187
Query: 210 KFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAR 269
F+ L P+V +L E E+ FPPYDAN+L IL RAE A GVL GVIP CAALAAR
Sbjct: 188 TFRNDLSPKVQDTLCEREIKFPPYDANELVTILDDRAERALSSGVLTGGVIPQCAALAAR 247
Query: 270 EHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLY 329
+ G AR+A+DLLR + +A + VTE V A ++E+ +++ IK L + +L
Sbjct: 248 DRGSARQAIDLLRESVNVAIEDERETVTEDDVETAVRRVERGRIKDSIKDLTTHGQYVLL 307
Query: 330 AIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKG 389
A+ D P E+Y VY ++ +PL+QR + D +N+L MLG + + G
Sbjct: 308 AVTQTAIADDTPVRAKELYEVYADIAAEYASDPLSQRSVHDHLNDLSMLGFLRQHDRNYG 367
Query: 390 RYG 392
R G
Sbjct: 368 RGG 370
>gi|10954477 ORF1 [Methanobacterium thermoautotrophicum]
>gi|267538|sp|P29570|YPZ1_METTF HYPOTHETICAL 40.6 KD
PROTEIN (ORF1') >gi|282613|pir||S26458 hypothetical
protein 1' - Methanobacterium thermoformicicum plasmid
pFZ1 >gi|44656|emb|CAA48438.1| (X68367) ORF1
[Methanobacterium thermoautotrophicum]
Length = 364
Score = 206 bits (520), Expect = 3e-52
Identities = 133/362 (36%), Positives = 200/362 (54%), Gaps = 30/362 (8%)
Query: 31 KARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVT 90
K K+FKN++VL + P L R E++ A++Q L +L G TP ++ + G G+GKTVT
Sbjct: 4 KRPKLFKNRDVLSPLFVPDTLQDRKEEVGAISQYLGYILDGATPPHLLIVGPPGSGKTVT 63
Query: 91 VKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDE 150
K+V EL +K+ + YI + T Y+V +I P G
Sbjct: 64 TKYVINEL----EKHTSDAVIEYIVAD--GTAYQVATSIAR---------APRRGLGFLN 108
Query: 151 VYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLK 210
+ K+++ E +IIV+DEIDK + + GD++LY L+R V ++G+SN L
Sbjct: 109 IVEKIRE--RASEGKMIIVMDEIDKTLSRDGDKLLYHLSR------EPNVCIVGLSNKLT 160
Query: 211 FKEYL-DPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAR 269
+ + D V+SS + F PY A QL++IL R E AF GVLE+ V+PLCAALAA+
Sbjct: 161 VMDMIGDSGVISSFKPRRISFAPYSAPQLEEILNYRVEMAFNDGVLEDDVVPLCAALAAQ 220
Query: 270 EHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLY 329
+GDAR ALDLL A +IA R+ V+E V A +++E + + I+ L K+LLY
Sbjct: 221 RNGDARYALDLLSFAADIAIRQLKGVVSESDVRMATDEVEVEFIRRSIEQLRDNQKILLY 280
Query: 330 AIVLLDENGDLPANTGEVYSVYRELC-EYLDLEPLTQRRISDLINELDMLGIINAKVVSK 388
A+ + G P E+Y Y ++ E LTQRR+S L+ EL++ G++ +VV +
Sbjct: 281 AV--MTSQGGTPT---EIYRKYNKMAEEQFGGNALTQRRLSQLLRELELYGLVEIEVVGR 335
Query: 389 GR 390
GR
Sbjct: 336 GR 337
>gi|10954475 orf1 [Methanobacterium thermoautotrophicum]
>gi|267528|sp|P29569|YPV1_METTF HYPOTHETICAL 40.7 KD
PROTEIN (ORF1) >gi|282612|pir||S26448 hypothetical
protein 1 - Methanobacterium thermoformicicum plasmid
pFV1 >gi|44645|emb|CAA48437.1| (X68366) orf1
[Methanobacterium thermoautotrophicum]
Length = 364
Score = 205 bits (517), Expect = 6e-52
Identities = 132/362 (36%), Positives = 201/362 (55%), Gaps = 30/362 (8%)
Query: 31 KARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVT 90
K ++FKN++VL + P L R E++ A++Q L +L G TP ++ + G G+GKTVT
Sbjct: 4 KRPRLFKNRDVLSPLFVPDTLQDRKEEVGAISQYLGYILDGATPPHLLIVGPPGSGKTVT 63
Query: 91 VKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDE 150
K+V EL +K+ + YI + T Y+V +I P G
Sbjct: 64 TKYVINEL----EKHTSDAVIEYIVAD--GTAYQVATSIAR---------APRRGLGFLN 108
Query: 151 VYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLK 210
+ K+++ E +IIV+DEIDK + + GD++LY L+R V ++G+SN L
Sbjct: 109 IVEKIRE--RASEGKMIIVMDEIDKTLSRDGDKLLYHLSR------EPNVCIVGLSNKLT 160
Query: 211 FKEYL-DPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAR 269
+ + D V+SS + F PY A QL++IL R E AF GVLE+ V+PLCAALAA+
Sbjct: 161 VMDMIGDSGVISSFKPRRISFAPYSAPQLEEILNYRVEMAFNDGVLEDDVVPLCAALAAQ 220
Query: 270 EHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLY 329
+GDAR ALDLL A +IA R+ V+E V A +++E + + I+ L K+LLY
Sbjct: 221 RNGDARYALDLLSFAADIAIRQLKGVVSESDVRMATDEVEVEFIRRSIEQLRDNQKILLY 280
Query: 330 AIVLLDENGDLPANTGEVYSVYRELC-EYLDLEPLTQRRISDLINELDMLGIINAKVVSK 388
A+ + +G P E+Y Y ++ E LTQRR+S L+ EL++ G++ +VV +
Sbjct: 281 AV--MTSHGGTPT---EIYRKYNKMTEEQFGGNALTQRRLSQLLRELELYGLVEIEVVGR 335
Query: 389 GR 390
GR
Sbjct: 336 GR 337
>gb|AAG20915.1| (AE005158) orc / cell division control protein 6; Orc5
[Halobacterium sp. NRC-1]
Length = 481
Score = 202 bits (509), Expect = 6e-51
Identities = 123/353 (34%), Positives = 196/353 (54%), Gaps = 17/353 (4%)
Query: 54 RHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIY 113
R EQ+E++ L P L+G P N+ +YG GTGK++ + VT+++ ++ V+
Sbjct: 84 RDEQLESVVSFLKPTLQGNRPPNMLLYGPAGTGKSLIIGAVTQQIIELCHSKGERFGVVQ 143
Query: 114 INCEIVDTHYRVLANIVNHFKDETGIE--VPLVGWPTDEVYAKLKQVIDMKERFVIIVLD 171
+NC+ ++T + + +V + GIE VP G T Y +L +I+ VI +LD
Sbjct: 144 VNCQPINTLDQAVYELVQTVASDVGIEPGVPETGVSTKRKYRRLYDLINEHYDSVIFILD 203
Query: 172 EIDKLV-KKSGDE-----VLYSLTRI-NTELKRAKVSVIGISNDLKFKEYLDPRVLSSLS 224
EID LV +++ DE +LY L+R NT +VSV ++ND KF E +D R SS +
Sbjct: 204 EIDLLVGRRANDEPAYSKLLYQLSRASNTNDIEGQVSVAALTNDPKFMENIDGRAESSFN 263
Query: 225 EEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVA 284
++ FP YDA QL+ IL R +AF L + V+PL +A AA+ HGDARKA+DL R A
Sbjct: 264 PRDIYFPDYDATQLRQILENR-RDAFRQDALTDDVLPLVSAFAAQSHGDARKAIDLFRGA 322
Query: 285 GEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDE-----NGD 339
G++A+ +G V E HV +Q++I++D ++I L Q K+ LYA +
Sbjct: 323 GDLADEQGDQTVREDHVRESQDEIDKDRSLKLIAGLTTQKKISLYATAAVAHCSSATRNS 382
Query: 340 LPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYG 392
+P+ G + VY+ + E +D + +T+ + EL G+++ S+GR G
Sbjct: 383 VPSPVG--FQVYQWVTEEIDADQMTRETYVKYVKELSTYGLVSTARKSRGRGG 433
>gb|AAK42358.1| Cell division control 6/orc1 protein homolog (cdc6-3) [Sulfolobus
solfataricus]
Length = 394
Score = 200 bits (503), Expect = 3e-50
Identities = 134/357 (37%), Positives = 206/357 (57%), Gaps = 28/357 (7%)
Query: 49 KDLPHRHEQIEALAQILVPVLKGETP-SNIFVYGKTGTGKTVTVKFV---TEELKKVSQK 104
K++P R + + A + +K E SN+F+ G TGTGKT K++ EE+KK ++
Sbjct: 30 KEIPFREDILRDAAIAIRYFVKNEVKFSNLFL-GLTGTGKTFVSKYIFNEIEEVKKEDEE 88
Query: 105 YNIPVEVIYINC-EIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKE 163
Y V+ Y+NC E+ T VL+++ TG VP G E K+K +
Sbjct: 89 YK-DVKQAYVNCREVGGTPQAVLSSLAGKL---TGFSVPKHGINLGEYIDKIKN--GTRN 142
Query: 164 RFVIIVLDEIDKLVKK-SGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSS 222
II LDE+D LVK+ GD VLY L R + A +SVI ISND+ ++Y++PRVLSS
Sbjct: 143 IRAIIYLDEVDTLVKRRGGDIVLYQLLRSD-----ANISVIMISNDINVRDYMEPRVLSS 197
Query: 223 LSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLR 282
L V+F PYDA QLK IL++ AE G ++ ++ AA++A+EHGDARKA++LL
Sbjct: 198 LGPS-VIFKPYDAEQLKFILSKYAEYGLIKGTYDDEILSYIAAISAKEHGDARKAVNLLF 256
Query: 283 VAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPA 342
A ++A G + ++HV +A EQ+ + E +K LP K+ L +++ E+ D+ +
Sbjct: 257 RAAQLA--SGGGIIRKEHVDKAIVDYEQERLIEAVKALPFHYKLALRSLI---ESEDVMS 311
Query: 343 NTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRL 399
+ +Y +LC +PL+ RR SD+I+ELDM GI+ +++++GR G K+ L
Sbjct: 312 ----AHKMYTDLCNKFKQKPLSYRRFSDIISELDMFGIVKIRIINRGRAGGVKKYAL 364
>gb|AAK41068.1| Cell division control 6/orc1 protein homolog (cdc6-2) [Sulfolobus
solfataricus]
Length = 413
Score = 168 bits (421), Expect = 1e-40
Identities = 118/414 (28%), Positives = 205/414 (49%), Gaps = 20/414 (4%)
Query: 23 DKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSN--IFVY 80
D L + L + I K+K+ L Y P++LPHR E+I+ L I +L G+ + + +
Sbjct: 6 DILSDSLRSSVLIIKHKDKLSPDYVPENLPHREEKIKELGFIFKDLLAGDAKDSERVVIL 65
Query: 81 GKTGTGKTVTVKFVTEELKKVSQK-YNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGI 139
G+TGTGKT TV+ + + ++++ Y + V+ ++INC T Y + I N K +
Sbjct: 66 GRTGTGKTATVRLFGKNFEDIAEREYGVKVKYVHINCYRHRTLYLISQEIANALK----L 121
Query: 140 EVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRA- 198
+P G EV+ + + +D + +I+ LDE + + E +Y L R+ E+
Sbjct: 122 PIPSRGLSAQEVFKMIHEYLDRRNIHLIVALDEFGHFLNTANTEEIYFLVRLYDEISAII 181
Query: 199 -KVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEE 257
++S I I N+ LD + ++ + FPPY + +L DIL R +EAF +++
Sbjct: 182 KRISYIFIVNESHSIYKLDRSIRDHIARRLIEFPPYKSMELYDILKYRVDEAFNDNAVDD 241
Query: 258 GVIPLCAALAARE---HGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMME 314
V+ + + +G+AR A++ L +AGEIAE+EG+ V H +A I ++ E
Sbjct: 242 EVLQFISNTYGYDKGGNGNARIAIETLSLAGEIAEKEGSPVVLLDHAKKANSTINPEIQE 301
Query: 315 --EVIKTLPLQSKVLLYAIV-LLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDL 371
+ + L L +LL A++ L++ G + Y L + EP ++ +
Sbjct: 302 IIDSLSYLDLHQLILLKALIRALNKTKADEITMGTLEEEYISLSREFNEEPRRHTQVYEY 361
Query: 372 INELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLLTVSLK 425
+ +L ++GIIN + KG GRT + L++ K R D I + V LK
Sbjct: 362 LRKLKVIGIINTRQSGKGMRGRTTLVSLSLPLDK-----RLDDYIMQQIMVRLK 410
>emb|CAB57532.1| (Y18930) cell division control 6 (cdc6) protein [Sulfolobus
solfataricus]
Length = 413
Score = 168 bits (421), Expect = 1e-40
Identities = 118/414 (28%), Positives = 205/414 (49%), Gaps = 20/414 (4%)
Query: 23 DKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSN--IFVY 80
D L + L + I K+K+ L Y P++LPHR E+I+ L I +L G+ + + +
Sbjct: 6 DILSDSLRSSVLIIKHKDKLSPDYVPENLPHREEKIKELGFIFKDLLAGDAKDSERVVIL 65
Query: 81 GKTGTGKTVTVKFVTEELKKVSQK-YNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGI 139
G+TGTGKT TV+ + + ++++ Y + V+ ++INC T Y + I N K +
Sbjct: 66 GRTGTGKTATVRLFGKNFEDIAEREYGVKVKYVHINCYRHRTLYLISQEIANALK----L 121
Query: 140 EVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRA- 198
+P G EV+ + + +D + +I+ LDE + + E +Y L R+ E+
Sbjct: 122 PIPSRGLSAQEVFKMIHEYLDRRNIHLIVALDEFGHFLNTANTEEIYFLVRLYDEISAII 181
Query: 199 -KVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEE 257
++S I I N+ LD + ++ + FPPY + +L DIL R +EAF +++
Sbjct: 182 KRISYIFIVNESHSIYKLDRSIRDHIARRLIEFPPYKSMELYDILKYRVDEAFNDNAVDD 241
Query: 258 GVIPLCAALAARE---HGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMME 314
V+ + + +G+AR A++ L +AGEIAE+EG+ V H +A I ++ E
Sbjct: 242 EVLQFISNTYGYDKGGNGNARIAIETLSLAGEIAEKEGSPVVLLDHAKKANSTINPEIQE 301
Query: 315 --EVIKTLPLQSKVLLYAIV-LLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDL 371
+ + L L +LL A++ L++ G + Y L + EP ++ +
Sbjct: 302 IIDSLSYLDLHQLILLKALIRALNKTKADEITMGTLEEEYISLSREFNEEPRRHTQVYEY 361
Query: 372 INELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLLTVSLK 425
+ +L ++GIIN + KG GRT + L++ K R D I + V LK
Sbjct: 362 LRKLKVIGIINTRQSGKGMRGRTTLVSLSLPLDK-----RLDDYIMQQIMVRLK 410
>pir||D69080 Cdc6 related protein - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622723|gb|AAB86072.1| (AE000919)
Cdc6 related protein [Methanobacterium
thermoautotrophicum]
Length = 379
Score = 159 bits (397), Expect = 8e-38
Identities = 101/368 (27%), Positives = 182/368 (49%), Gaps = 19/368 (5%)
Query: 29 LLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKT 88
LL +F+N Y P++ +R Q+EALA + P L+ P N + G TGKT
Sbjct: 13 LLHDETLFRNMNAFDPDYVPENYRYRESQMEALAVCIRPALRNGRPVNAVILGSCATGKT 72
Query: 89 VTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPT 148
+K + E ++ S+ V YINC++ T + + + I + G + P G P
Sbjct: 73 TAIKKIFEMVESTSEG----VVCCYINCQLHTTRFGIFSQIYSKI---FGHQPPETGVPF 125
Query: 149 DEVYAKLKQVIDMKERFVIIVLDEIDKLV-KKSGDEVLYSLTRINTELKRAKVSVIGISN 207
+Y + Q + ++R +++ LD+I+ L K+ ++VLY + R + + + V + +
Sbjct: 126 SRIYQTIMQHLASEKRALVVALDDINHLFYSKNANKVLYDILRAHEVFEGVRTGVFAVLS 185
Query: 208 DLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALA 267
D++F+ LD V S +E+VFPPY ++ +IL R FYPGV+ + ++
Sbjct: 186 DIEFRYALDKNVDSIFIPQEIVFPPYTREEVFNILRDRVRVGFYPGVISDELLERITD-H 244
Query: 268 AREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVL 327
+ GD R +DLLRV G +AE + + + E+H+ RA + + ++TL +
Sbjct: 245 TMDTGDLRYGIDLLRVCGNLAEADASPVIGEEHLERALKSTGPVNLIHTVRTLNENEREF 304
Query: 328 LYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVS 387
L +L D D+ A G +Y ++RE + + +I +L+ L +I+ ++
Sbjct: 305 LR--ILADAGEDMTA--GALYELFRE------STGSSYSSFNRIIEKLEFLRLIDTRLTG 354
Query: 388 KGRYGRTK 395
KG G ++
Sbjct: 355 KGVRGNSR 362
>gb|AAG20387.1| (AE005112) orc / cell division control protein 6; Orc6
[Halobacterium sp. NRC-1]
Length = 374
Score = 148 bits (370), Expect = 1e-34
Identities = 106/370 (28%), Positives = 177/370 (47%), Gaps = 27/370 (7%)
Query: 35 IFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFV 94
+F+++ V Y P+ HR Q++ L L P ++G P N+ G GTGKT V+ +
Sbjct: 16 VFRDEHVFEIDYVPEVFRHRESQLQTLQYALRPAVRGSRPLNVVARGPPGTGKTTAVQKL 75
Query: 95 TEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAK 154
EL V+ + +NC++ T Y V + + F++ E P G +++ +
Sbjct: 76 FGELSG-----QPGVQTVRVNCQVDSTRYAVFSRV---FEEIFDYEPPSSGISFKKLFGQ 127
Query: 155 LKQVIDMKERFVIIVLDEIDKL-VKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFK- 212
+ + I + +++ LD+++ L + + LYSL R + AKV V+ +S+DL+
Sbjct: 128 VAERIADDDEVLVVALDDVNYLFYEDEAGDTLYSLLRAHETQPGAKVGVVVVSSDLELDV 187
Query: 213 -EYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAR-- 269
E LD RV S EE F YD ++ DIL R E F G + E P+ A+ R
Sbjct: 188 IEALDGRVQSVFRPEEAYFSAYDRAEITDILRDRVEVGFREGAVAE---PVLDAVGGRTD 244
Query: 270 EHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLY 329
E GD R +D+LR AG AE + V + V E + + + L + L+
Sbjct: 245 EAGDLRVGIDVLRRAGLHAESRASKTVEMEDVDAVYEDAKHVHLSRTLAALSDNERALVR 304
Query: 330 AIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKG 389
+ ++ GD G+VY V+ D L R ++++N+LD LG+I+A +
Sbjct: 305 TVA--EQEGD---RAGDVYDVFN------DRTDLGYTRYTEIVNKLDELGVIDAAYEQRS 353
Query: 390 RYGRTKEIRL 399
GR++ +RL
Sbjct: 354 GRGRSRTLRL 363
>gi|11498302 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7429756|pir||G69336 conserved hypothetical protein
AF0695 - Archaeoglobus fulgidus
>gi|2649923|gb|AAB90547.1| (AE001057) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 376
Score = 132 bits (328), Expect = 9e-30
Identities = 105/384 (27%), Positives = 182/384 (47%), Gaps = 34/384 (8%)
Query: 20 LHLDKLFERLLK-ARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIF 78
+H++ F +L +FKN EV Y P +L R QI L + P + +P N F
Sbjct: 7 IHINVSFTLMLSWDETLFKNPEVFDPDYIPDELLFRDGQIRQLVSCIKPAMLNSSPINAF 66
Query: 79 VYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETG 138
G TGKT T+++V E ++ + YI Y+V + I F+D G
Sbjct: 67 CLGPPSTGKTSTIRYVLREAER-----ETGLLYSYIRIPRFKEPYKVFSKI---FQDVLG 118
Query: 139 IEVPLVGWP----TDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTE 194
+ P G D V++ L + + ++VLD+I+ L K +E+LY + + E
Sbjct: 119 QQSPPSGISKTVLMDRVWSNLDEPL-------LVVLDDINFLGKNYANEILYEILKAPDE 171
Query: 195 LKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGV 254
KV ++ + D+KF LDP V +S E+ +P Y +++ IL +R E FY GV
Sbjct: 172 Y-GVKVGIVAAATDVKFPLLLDPFVGASFHYMEIHYPSYGYAEIEGILRKRVEHGFYEGV 230
Query: 255 LEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMME 314
++G LA R D R + LL+ AG AE G+ KV E+ V A +
Sbjct: 231 FDDGAFRRVVELAYRA-SDVRYGIYLLKAAGMNAESRGSRKVEERDVEVAHAGESLSFIA 289
Query: 315 EVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINE 374
+++ L + + +L ++ +N +TG+ +Y ++C + ++ R+ +++ +
Sbjct: 290 KILTALNSEERAVLR--MIYSQNA---ISTGD---LYEQVCSEI---KMSYRKYYNILEK 338
Query: 375 LDMLGIINAKVVSKGRYGRTKEIR 398
L+ L +I KGR G+T+ ++
Sbjct: 339 LERLKLIEISFGEKGR-GKTRYVQ 361
>gb|AAG20835.1| (AE005152) orc / cell division control protein 6; Orc2
[Halobacterium sp. NRC-1]
Length = 264
Score = 126 bits (314), Expect = 4e-28
Identities = 80/230 (34%), Positives = 128/230 (54%), Gaps = 12/230 (5%)
Query: 23 DKLFERLLKARKIFKNKEVLRHSYTPKD--LPHRHEQIEALAQILVPVLKGETPSNIFVY 80
D LFE +IF NK++L+ + P+ + R E+I LA+ L + G +P N+ +Y
Sbjct: 12 DPLFE---SGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGYSPENVMIY 68
Query: 81 GKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDE--TG 138
GKTGTGK++ K V + + +Q + + YI+C +T + ++++ +E TG
Sbjct: 69 GKTGTGKSLVSKHVCQRAQNAAQD-GVEIGTAYIDCAEDNTETQAISSLAAKLNNESSTG 127
Query: 139 IEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELK-R 197
I VP G T + Y L + +D + VII+LDEID + + D VL L+R K
Sbjct: 128 ISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILDEIDLM---NDDSVLMKLSRAEEAGKID 184
Query: 198 AKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAE 247
V VI ISN +++ + ++ RV SS +E+ F PYDANQL++I+ R +
Sbjct: 185 CSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNRED 234
>gi|10803617 ORF H0761 [Halobacterium sp. NRC-1] >gi|7484055|pir||T08287 cell
division control protein 6 homolog H0761 - Halobacterium
sp. (strain NRC-1) plasmid pNRC100
>gi|2822348|gb|AAC82854.1| (AF016485) ORF H0761
[Halobacterium sp. NRC-1] >gi|10584152|gb|AAG20777.1|
(AE005146) orc / cell division control protein 6; Orc9
[Halobacterium sp. NRC-1]
Length = 354
Score = 123 bits (306), Expect = 4e-27
Identities = 100/357 (28%), Positives = 172/357 (48%), Gaps = 30/357 (8%)
Query: 35 IFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFV 94
+ ++ VLR + P+++ HR ++ L+ +L P+ GE V G +GTGKT +FV
Sbjct: 13 MIRDARVLRAGFVPREVEHRDAEVNHLSSVLEPITNGEPADTAIVTGPSGTGKTCISQFV 72
Query: 95 TEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAK 154
TE L++ + VE Y+NC T +R L I++ F + I++ P DE+ +
Sbjct: 73 TERLREEV----LNVEATYVNCWRNYTRFRTLYQILDDFGET--IDIHRQSTPHDELIDR 126
Query: 155 LKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEY 214
L+Q + +I+LDE+D+L L+SL A + + DL +
Sbjct: 127 LQQYDGPR---TVIILDEVDQLEDPGIIYDLHSLPHF------AVICIANKEEDLFSR-- 175
Query: 215 LDPRVLSSL-SEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGD 273
+D R++S L S E V Y QL DIL R + V+ + A AA GD
Sbjct: 176 VDDRLVSRLRSSEHVRMDKYHDEQLHDILAARVKGGLDQDVITTNQLDRIADAAA---GD 232
Query: 274 ARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVL 333
AR A+ +LR A A+RE ++T+ + A E + ++ + +L + + L+Y +V
Sbjct: 233 ARLAIGILRTAASKADRESRERITDDILLNAAEDARAQIKQKNLDSL-IPHQRLVYDVV- 290
Query: 334 LDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGR 390
E+G P E+Y Y+ + +P T+R I ++++ ++ A+ S+ R
Sbjct: 291 -REHG--PLGPSEIYDHYKRKVD----DPRTKRTIRTYLSKMTQYNVLEAEGTSRDR 340
>pdb|1FNN|A Chain A, Crystal Structure Of Cdc6p From Pyrobaculum Aerophilum
>gi|10835435|pdb|1FNN|B Chain B, Crystal Structure Of
Cdc6p From Pyrobaculum Aerophilum
Length = 389
Score = 119 bits (296), Expect = 5e-26
Identities = 100/384 (26%), Positives = 175/384 (45%), Gaps = 29/384 (7%)
Query: 35 IFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLK--GETPSNIFVYGKTGTGKTVTVK 92
I + V SY PK LPHR +Q++ L +L L+ G + G+ GTGKTVT++
Sbjct: 3 IVVDDSVFSPSYVPKRLPHREQQLQQLDILLGNWLRNPGHHYPRATLLGRPGTGKTVTLR 62
Query: 93 FVTEELK-KVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEV 151
+ E K K + ++ +YIN I YR I+ I P G DE
Sbjct: 63 KLWELYKDKTTARF------VYINGFI----YRNFTAIIGEIARSLNIPFPRRGLSRDEF 112
Query: 152 YAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRA---KVSVIGISND 208
A L + + ++ ++ +VLD+ L ++L + R+ E + +++++ + ++
Sbjct: 113 LALLVEHLRERDLYMFLVLDDAFNLAP----DILSTFIRLGQEADKLGAFRIALVIVGHN 168
Query: 209 LKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAA 268
LDP + + + F PY +Q+ DIL RA+ G E ++ + A +
Sbjct: 169 DAVLNNLDPSTRGIMGKYVIRFSPYTKDQIFDILLDRAKAGLAEGSYSEDILQMIADITG 228
Query: 269 RE------HGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPL 322
+ GDAR A+D+L + A++ G + + V ++ +++ + EEV+ LPL
Sbjct: 229 AQTPLDTNRGDARLAIDILYRSAYAAQQNGRKHIAPEDVRKSSKEVLFGISEEVLIGLPL 288
Query: 323 QSKVLLYAIVLLDENGDLPANT-GEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGII 381
K+ L AIV + P T G+ Y+ +CE P ++ +N+L GI+
Sbjct: 289 HEKLFLLAIVRSLKISHTPYITFGDAEESYKIVCEEYGERPRVHSQLWSYLNDLREKGIV 348
Query: 382 NAKVVSKGR--YGRTKEIRLNVTP 403
+ +G GRT I + P
Sbjct: 349 ETRQNKRGEGVRGRTTLISIGTEP 372
>gi|4502703 CDC6 (cell division cycle 6, S. cerevisiae) homolog; CDC18 (cell
division cycle 18, S.pombe, homolog)-like [Homo sapiens]
>gi|1684903|gb|AAB38317.1| (U77949) Cdc6-related protein
[Homo sapiens] >gi|2465437|gb|AAC52071.1| (AF022109)
HsCdc18p [Homo sapiens]
Length = 560
Score = 113 bits (281), Expect = 3e-24
Identities = 103/400 (25%), Positives = 179/400 (44%), Gaps = 49/400 (12%)
Query: 36 FKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVT 95
++ +++ ++ P LP R +++ + L + G+ ++++ G GTGKT + +
Sbjct: 157 YQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRIL 216
Query: 96 EELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTD-EVYAK 154
++LKK + + + I +NC + T V I E V P ++ K
Sbjct: 217 QDLKKELKGF----KTIMLNCMSLRTAQAVFPAIAQEICQEE------VSRPAGKDMMRK 266
Query: 155 L-KQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE 213
L K + K +++VLDE+D+L K G +VLY+L L + + +IGI+N L +
Sbjct: 267 LEKHMTAEKGPMIVLVLDEMDQLDSK-GQDVLYTLFEWPW-LSNSHLVLIGIANTLDLTD 324
Query: 214 YLDPRVLS--SLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREH 271
+ PR+ + + + FPPY NQ+ IL R + VL+ + CA +
Sbjct: 325 RILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVS 384
Query: 272 GDARKALDLLRVAGEIAEREGASKVTEK--------------------HVWRAQEKIEQD 311
GD RKALD+ R A EI E + S+ K H+ + +++ +
Sbjct: 385 GDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGN 444
Query: 312 MM----EEVIKTLPLQSKVLLYAIVLLDENGDLPANT-GEVYSVYRELCEYLDLEPLTQR 366
M E + PLQ K+L+ +++LL + T G++Y Y ++C + + Q
Sbjct: 445 RMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQS 504
Query: 367 RISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKI 406
L L+ GI+ K R KE RL +KI
Sbjct: 505 ECLSLSGLLEARGILGLK--------RNKETRLTKVFFKI 536
>gi|6753368 cell division cycle 6 homolog (S. cerevisiae); CDC18(S.pombe); cell
division cycle 18 homolog (S.pombe)-like [Mus musculus]
>gi|3646345|emb|CAA08752.1| (AJ009559) CDC6 protein [Mus
musculus] >gi|4049492|emb|CAA11110.1| (AJ223087)
Cdc6-related protein [Mus musculus]
Length = 589
Score = 111 bits (276), Expect = 1e-23
Identities = 98/401 (24%), Positives = 181/401 (44%), Gaps = 40/401 (9%)
Query: 36 FKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVT 95
++ +++ ++ P LP R +++ + L + G+ ++++ G GTGKT + +
Sbjct: 186 YQQAKLVLNTAVPDRLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRIL 245
Query: 96 EELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKL 155
++ KK + + + I +NC + + V I E G E D +
Sbjct: 246 QDFKKEVKGF----KSILLNCMSLRSAQAVFPAIAQ----EIGREELCRPAGKDLMRKLE 297
Query: 156 KQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYL 215
K + K +++VLDE+D+L K G +VLY+L L +++ +IGI+N L + +
Sbjct: 298 KHLTAEKGPMIVLVLDEMDQLDSK-GQDVLYTLFEWPW-LSNSRLVLIGIANTLDLTDRI 355
Query: 216 DPRVLS--SLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGD 273
PR+ + + + + FPPY NQ+ IL R + VL+ I CA + GD
Sbjct: 356 LPRLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGD 415
Query: 274 ARKALDLLRVAGEIAEREGASKVTEK--------------------HVWRAQEKIEQDMM 313
RKALD+ R A EI E + S+ K H+ + +++ + +
Sbjct: 416 IRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPSESPVPKRVGLAHISQVISEVDGNRV 475
Query: 314 ----EEVIKTLPLQSKVLLYAIVLLDENGDLPANT-GEVYSVYRELCEYLDLEPLTQRRI 368
E +LPLQ K+L+ +++LL + T G++Y Y +C + + Q
Sbjct: 476 TLSQENTQDSLPLQQKILVCSLLLLTRRLKIKEVTLGKLYEAYSSICRKQQVTAVDQSEC 535
Query: 369 SDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNV 409
L L+ G++ K K + R ++ L + +I +V
Sbjct: 536 LSLSGLLESRGLVGLK---KNKESRLTKVSLKIEEKEIEHV 573
>pir||E72770 hypothetical protein APE0152 - Aeropyrum pernix (strain K1)
>gi|5103542|dbj|BAA79063.1| (AP000058) 412aa long
hypothetical protein [Aeropyrum pernix]
Length = 412
Score = 109 bits (270), Expect = 6e-23
Identities = 98/383 (25%), Positives = 182/383 (46%), Gaps = 22/383 (5%)
Query: 35 IFKNKEVLRHSYTPKDLPHRHEQIEALAQI-LVPVLKGETPSNI-FVYG---KTGTGKTV 89
+FK++ V +Y P +L R + EALA+I L +L G S++ +YG + G GKT
Sbjct: 8 LFKDRRVFDENYIPPELRVRRGEAEALARIYLNRLLSGAGLSDVNMIYGSIGRVGIGKTT 67
Query: 90 TVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTD 149
KF + + + + K + V+ Y+N Y +L+ IV +TG + + G P
Sbjct: 68 LAKFTVKRVSEAAAKEGLTVKQAYVNAFNAPNLYTILSLIVR----QTGYPIQVRGAPAL 123
Query: 150 EVYAKLKQVIDMKERFVIIVLDEIDKLVK--KSGDEVLYSLTRINTEL-KRAKVSVIG-- 204
++ L + ++ +++++LDE ++ + E LY+L R++ E+ R V+ IG
Sbjct: 124 DILKALVDNLYVENHYLLVILDEFQSMLSSPRIAAEDLYTLLRVHEEIPSRDGVNRIGFL 183
Query: 205 -ISNDLKFKEYLDPRV--LSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIP 261
+++D++ Y+ ++ + S ++ P Y + +L IL QRAE V E +
Sbjct: 184 LVASDVRALSYMREKIPQVESQIGFKLHLPAYKSRELYTILEQRAELGLRDTVWEPRHLE 243
Query: 262 LCAALAARE---HGDARKALDLLRVAGEIAEREGASKVTEKHVWRA-QEKIEQDMMEEVI 317
L + + + G AR+A+ L++A E+AE G ++E V +A E + +
Sbjct: 244 LISDVYGEDKGGDGSARRAIVALKMACEMAEAMGRDSLSEDLVRKAVSENEAASIQTHEL 303
Query: 318 KTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYREL-CEYLDLEPLTQRRISDLINELD 376
+ L + ++L I G N G + Y + +++P + + L
Sbjct: 304 EALSIHELIILRLIAEATLGGMEWINAGLLRQRYEDASLTMYNVKPRGYTQYHIYLKHLT 363
Query: 377 MLGIINAKVVSKGRYGRTKEIRL 399
LG+++AK +G GRT RL
Sbjct: 364 SLGLVDAKPSGRGMRGRTTLFRL 386
>gb|AAF50387.1| (AE003554) CG5971 gene product [Drosophila melanogaster]
Length = 662
Score = 109 bits (269), Expect = 8e-23
Identities = 101/405 (24%), Positives = 187/405 (45%), Gaps = 59/405 (14%)
Query: 32 ARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTV 91
+R ++N + +S ++LP R Q++ L + L+ +T +++V G+ GTGKT +
Sbjct: 248 SRNKYQNARRVLNSAETQNLPGRESQLQELREFFSNHLESQTSGSLYVSGQPGTGKTACL 307
Query: 92 KFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEV 151
+ + ++ ++ +YINC + + V + T +++ + G +
Sbjct: 308 SLLLRD-----PDFSKRLQRVYINCTSIASVGAVYKKLC------TELQLKVSGRTERDH 356
Query: 152 YAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISN--DL 209
+++ + +R +++VLDEID+L S EVLY++ L +++ ++GI+N DL
Sbjct: 357 LEAIQRHLKTAKRMLLLVLDEIDQLCT-SRQEVLYTIFEWPA-LPGSRILLVGIANSLDL 414
Query: 210 KFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAR 269
+ + L + FPPY Q+ +I R EA V + L AA +
Sbjct: 415 TDRALMRLNARCELKPRLMHFPPYSKQQIVEIFKSRLAEAEVLDVFPPVTLQLLAAKVSA 474
Query: 270 EHGDARKALDLLRVAGEIAE---REG-------ASKVTEKHVWRAQEK------------ 307
GD R+ALD+ R EIAE R+G A ++ K A+EK
Sbjct: 475 ISGDVRRALDIGRRVVEIAEQQKRDGEKEFNMKALQLEGKDAVEAKEKQDTLKPVQVTQV 534
Query: 308 ---------IEQDMMEEVIKTLPLQSKVLLYAIVLL---DENGDLPANTGEVYSVYRELC 355
Q++ E++ + PLQ K++L +VL+ + N D+ + G ++ VYR +C
Sbjct: 535 AAVLNKVYGASQNLEEDIEASFPLQQKLMLCTLVLMLRNERNKDI--SMGRLHEVYRRVC 592
Query: 356 EYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLN 400
++ L Q + ++ ++ GI+ R R KE RL+
Sbjct: 593 AKRNILALDQAEFTGTVDLVETRGIL--------RIMRKKEPRLH 629
>pir||T26734 hypothetical protein Y39A1A.12 - Caenorhabditis elegans
>gi|3880850|emb|CAA21023.1| (AL031633) contains
similarity to Pfam domain: PF00004 (ATPases associated
with various cellular activities (AAA)), Score=-1.1,
E-value=1e-05, N=1~cDNA EST yk33b7.3 comes from this
gene~cDNA EST yk33b7.5 comes from this gene~cDNA EST
yk117h1.3 comes fr>
Length = 636
Score = 104 bits (257), Expect = 2e-21
Identities = 107/410 (26%), Positives = 185/410 (45%), Gaps = 29/410 (7%)
Query: 6 TISTGGTSMSEGEQLH--LDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRH---EQIEA 60
T+ T + E+L +D L R K ++ L S P+ LP R +IE
Sbjct: 222 TLRTRRRARQNSEELEDLVDPLDSRSASTLKELASR--LHLSKVPEKLPCRDIESREIEK 279
Query: 61 LAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVD 120
+ ++ +GE+ S +++ G GTGKT TV+ V +KK S+K + +Y+ +
Sbjct: 280 FIREVIDPKRGES-SAMYISGVPGTGKTATVRAVVNSMKK-SKKCQ---KFVYVEVNAMI 334
Query: 121 THYRVLANIVNHFKDETGIE-----VPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDK 175
V I N ++E I + + + + D K +++++DE+D
Sbjct: 335 FKKTVFVEIYNGIQEEYNISKKPQRAKITATAARQELNSIFKREDPKRPPIVVLIDELDS 394
Query: 176 LVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YLDPRVLSSLSEEEVVFPPYD 234
L + D VLY + T L ++KV++IGI+N L F E L R S L + +VF PY
Sbjct: 395 LCNRKQD-VLYDIFEW-TALPQSKVTIIGIANTLDFPERMLCQRNASRLDKRRLVFQPYQ 452
Query: 235 ANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGAS 294
Q+++I+ R + + +++ + L A A GD R+ALD L A +A +
Sbjct: 453 HEQIEEIVRARLQGS---NLIDPKAVELVAKKVAMNTGDLRQALDFLCRAIRVAVERKSE 509
Query: 295 KVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYREL 354
K+ HV AQ + + + ++K L L L I + + +Y Y +
Sbjct: 510 KLELSHVIAAQNAVLEPLKYRLVKGLRLHQFTLFRTIESMTREQE-EIIFANIYKNYCII 568
Query: 355 C-EYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYG-RTKEIRLNVT 402
C E + P T ++ +L +IN +SKG +G + ++L +T
Sbjct: 569 CSEVSGIGPATDSFAYGMLLQLASTSLIN---LSKGDHGMMNRRVKLGMT 615
>gb|AAG20823.1| (AE005151) orc / cell division control protein 6; Orc1
[Halobacterium sp. NRC-1]
Length = 308
Score = 102 bits (253), Expect = 6e-21
Identities = 89/331 (26%), Positives = 161/331 (47%), Gaps = 34/331 (10%)
Query: 41 VLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKK 100
VL+ + P+++ HR ++ L+ +L P+ KGE + +YG +G GKT +F+ E+L+
Sbjct: 7 VLQPEFIPREVQHRDAEVNYLSSVLNPLTKGERADSALLYGPSGVGKTCIAQFLVEQLRG 66
Query: 101 VSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVID 160
N Y+NC + ++ L +++ +++ PTD +L+ D
Sbjct: 67 EVVALNYQ----YVNCWEDHSRFQTLYRLLDGIGKT--VDIHRQSTPTDVHLNRLRTADD 120
Query: 161 MKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLK-FKEYLDPRV 219
+++LDE+D+L KS +LY L RI +++I I+ND + LD R+
Sbjct: 121 TS---YVVILDEVDQLEDKS---LLYDLYRI------PHITMILIANDEEDLFASLDQRL 168
Query: 220 LSSLSE-EEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKAL 278
S L++ E + F PY N+L IL R V+ + + L AA A GDAR +
Sbjct: 169 NSRLTDCERIHFDPYHENELIPILHDRVHWGLEEDVISDSHLQLIAANAG---GDARVVI 225
Query: 279 DLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVI-KTLPLQSKVLLYAIVLLDEN 337
+LR + A G+ ++T + + + ++ + + + P Q LLY I+ E+
Sbjct: 226 GILRHSARTARETGSDQITADLIEEVTPEAKSEIKQRTVDRFTPHQE--LLYNII--TEH 281
Query: 338 GDLPANTGEVYSVYRELCEYLDLEPLTQRRI 368
G++ + ++Y Y C D +P T+R +
Sbjct: 282 GEI--SPQDLYDAY---CTRTD-DPKTKRMV 306
>gb|AAC69366.1| (U76834) Cdc6-related protein [Xenopus laevis]
Length = 554
Score = 101 bits (250), Expect = 1e-20
Identities = 96/394 (24%), Positives = 172/394 (43%), Gaps = 45/394 (11%)
Query: 48 PKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNI 107
P+ L R + + L + ++++ G GTGKT + + +E K ++
Sbjct: 163 PERLLARESETAFIKTFLTSHVSARKAGSLYISGAPGTGKTACLNKLLQESKDDLKQ--- 219
Query: 108 PVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVI 167
+ +YINC + + V I +G + L ++ L++++ K ++
Sbjct: 220 -CKTVYINCMSLRSSQAVFPAIAEEI---SGGKSSLAA---KDMVRNLEKLVTSKGPIIL 272
Query: 168 IVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLS--SLSE 225
+VLDE+D+L + G +VLY++ L +++ +IGI+N L + + PR+ +
Sbjct: 273 LVLDEMDQLDSR-GQDVLYTVFEWPW-LPNSRMVLIGIANALDLTDRILPRLQARPQCKP 330
Query: 226 EEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAG 285
+ + F PY +Q+ IL R + VL+ I CA + GDARKALD+ R A
Sbjct: 331 QLLNFSPYTKDQIATILQDRLNQVSGDQVLDNAAIQFCARKISAVSGDARKALDICRRAV 390
Query: 286 EIAE-------------------REGAS-----KVTEKHVWRAQEKIEQDMMEE---VIK 318
EI E +E S KV+ H+ R + D M
Sbjct: 391 EIVEADVRGQTVLKPLTECLSPSKEAPSNPVPKKVSLPHISRVLSDVYGDKMASNGGSSD 450
Query: 319 TLPLQSKVLLYAIVLLDENGDLPANT-GEVYSVYRELCEYLDLEPLTQRRISDLINELDM 377
+ PLQ K+L+ A++L+ + T G+V+ Y ++C + + Q L L+
Sbjct: 451 SFPLQQKLLVCALLLITRQSKIKEVTLGKVHEAYSKVCRKQQVPGVGQSECLSLCQLLET 510
Query: 378 LGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFR 411
GI+ K K + R ++ L + I + F+
Sbjct: 511 RGILGLK---KAKEARLTKVSLKIEERDIEHAFK 541
>pir||T46977 cell division control protein 6 [validated] - African clawed frog
>gi|1655928|gb|AAB17973.1| (U66558) cell division
control protein 6 [Xenopus laevis]
Length = 554
Score = 98.7 bits (242), Expect = 1e-19
Identities = 95/394 (24%), Positives = 171/394 (43%), Gaps = 45/394 (11%)
Query: 48 PKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNI 107
P+ L R + + L + ++++ G GTGKT + + +E K ++
Sbjct: 163 PERLLARESETAFIKTFLTSHVSAGKAGSLYISGAPGTGKTACLNKLLQESKDDLKQ--- 219
Query: 108 PVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVI 167
+ +YINC + + V I +G + L ++ L++++ K ++
Sbjct: 220 -CKTVYINCMSLRSSQAVFPAIAEEI---SGGKSSLAA---KDMVRNLEKLVTSKGPIIL 272
Query: 168 IVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLS--SLSE 225
+VLDE+D+L + G +VLY++ L +++ +IGI+N L + + PR+ +
Sbjct: 273 LVLDEMDQLDSR-GQDVLYTVFEWPW-LPNSRMVLIGIANALDLTDRILPRLQARPQCKP 330
Query: 226 EEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAG 285
+ + F PY +Q+ IL R + VL+ I CA + GDARKALD+ R A
Sbjct: 331 QLLNFSPYTKDQIATILQDRLNQVSGDQVLDNAAIQFCARKISAVSGDARKALDICRRAV 390
Query: 286 EIAE-------------------REGAS-----KVTEKHVWRAQEKIEQDMME---EVIK 318
EI E +E S K + H+ R + D M
Sbjct: 391 EIVEADVRGQTVLKPLTECLSPSKEAPSNPVPKKASLPHISRVLSDVYGDKMAINGGSSD 450
Query: 319 TLPLQSKVLLYAIVLLDENGDLPANT-GEVYSVYRELCEYLDLEPLTQRRISDLINELDM 377
+ PLQ K+L+ A++L+ + T G+V+ Y ++C + + Q L L+
Sbjct: 451 SFPLQQKLLVCALLLITRQSKIKEVTLGKVHEAYSKVCRKQQVPGVGQSECLSLCQLLET 510
Query: 378 LGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFR 411
GI+ K K + R ++ L + I + F+
Sbjct: 511 RGILGLK---KAKEARLTKVSLKIEERDIEHAFK 541
>emb|CAB53755.1| (AL049730) origin recognition complex subunit 1-like protein
[Arabidopsis thaliana] >gi|7267964|emb|CAB78305.1|
(AL161534) origin recognition complex subunit 1-like
protein [Arabidopsis thaliana]
Length = 813
Score = 98.7 bits (242), Expect = 1e-19
Identities = 89/354 (25%), Positives = 173/354 (48%), Gaps = 43/354 (12%)
Query: 6 TISTGGTSMSEGEQLHLDKLFERLL-------KARKIFKNKEVLRHSYTPKDLPHRHEQI 58
T + GG + +G ++K+ +L+ K ++ K K L + PK LP R +++
Sbjct: 387 TSARGGANSRKGRFFGVEKVGMKLIPEHVRCHKQSELEKAKATLLLATRPKSLPCRSKEM 446
Query: 59 EALAQILVPVLKGETPSN--IFVYGKTGTGKTVTVKFVTEELKKVSQKYNIP----VEVI 112
E + + + + ++++G GTGKT++V V + LK ++ ++ VE+
Sbjct: 447 EEITSFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVMKNLKAEVEEGSVSPYCFVEIN 506
Query: 113 YINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPT-----DEVYAKLKQVIDMKERFVI 167
+ + Y V+ ++ + VGW +E +A+ K++ E+ I
Sbjct: 507 GLKLASPENIYSVIYEALSGHR---------VGWKKALQCLNERFAEGKRIGKEDEKPCI 557
Query: 168 IVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEE 227
+++DE+D LV ++ VLY++ T+ +K+ V+GI+N + E L PR+ S + +
Sbjct: 558 LLIDELDLLVTRN-QSVLYNILDWPTK-PNSKLVVLGIANTMDLPEKLLPRISSRMGIQR 615
Query: 228 VVFPPYDANQLKDILTQRAE--EAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAG 285
+ F PY+ QL++I++ R +AF E+ I + A GDAR+AL++ R A
Sbjct: 616 LCFGPYNHTQLQEIISTRLNGIDAF-----EKTAIEFASRKVAAISGDARRALEICRRAA 670
Query: 286 EIAEREGASKVTEKHVWRAQEKIEQDMME-------EVIKTLPLQSKVLLYAIV 332
E+A+ + + K+ +E + E +V+K++ SK+ L A+V
Sbjct: 671 EVADHRLNTNKSAKNQLVIMADVEAAIQEMFQAPHIQVMKSVSKLSKIFLTAMV 724
>pir||G71409 probable replication control protein - Arabidopsis thaliana
>gi|2244826|emb|CAB10249.1| (Z97336) replication control
protein 1 like [Arabidopsis thaliana]
>gi|7268176|emb|CAB78512.1| (AL161539) replication
control protein 1 like [Arabidopsis thaliana]
Length = 771
Score = 96.7 bits (237), Expect = 4e-19
Identities = 91/349 (26%), Positives = 168/349 (48%), Gaps = 40/349 (11%)
Query: 10 GGTSMSEGEQLHLDKL-------FERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALA 62
GG + +G L+K+ R K ++ K K L + PK LP R +++E +
Sbjct: 348 GGANSRKGRFFGLEKVGMKRIPEHVRCHKQSELEKAKATLLLATRPKSLPCRSKEMEEIT 407
Query: 63 QILVPVLKGETPSN--IFVYGKTGTGKTVTVKFVTEELKKVSQKYNIP----VEVIYINC 116
+ + + ++++G GTGKT++V V + LK + ++ VE+ +
Sbjct: 408 AFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVMKNLKAEVEAGSVSPYCFVEINGLKL 467
Query: 117 EIVDTHYRVLANIVNHFKDETGIEVPLVGWPT-----DEVYAKLKQVIDMKERFVIIVLD 171
+ Y V+ G+ VGW +E +A+ K++ E+ I+++D
Sbjct: 468 ASPENIYSVIYE---------GLSGHRVGWKKALQSLNERFAEGKKIGKENEKPCILLID 518
Query: 172 EIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFP 231
E+D LV ++ VLY++ T+ +K+ V+GI+N + E L PR+ S + + + F
Sbjct: 519 ELDVLVTRN-QSVLYNILDWPTK-PNSKLVVLGIANTMDLPEKLLPRISSRMGIQRLCFG 576
Query: 232 PYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAE-R 290
PY+ QL++I++ R E E+ I + A GDAR+AL++ R A E+A+ R
Sbjct: 577 PYNHRQLQEIISTRLEGI---NAFEKTAIEFASRKVAAISGDARRALEICRRAAEVADYR 633
Query: 291 EGASKVTEKHVWRAQEKIE---QDMME----EVIKTLPLQSKVLLYAIV 332
S ++ K +E Q+M + +V+K++ S++ L A+V
Sbjct: 634 LKKSNISAKSQLVIMADVEVAIQEMFQAPHIQVMKSVSKLSRIFLTAMV 682
>sp|P54789|ORC1_SCHPO ORIGIN RECOGNITION COMPLEX SUBUNIT 1 >gi|7492260|pir||T40070 origin
recognition complex protein, subunit 1 - fission yeast
(Schizosaccharomyces pombe) >gi|1127741|gb|AAC49129.1|
(U38522) Orp1 [Schizosaccharomyces pombe]
>gi|1161930|gb|AAC49141.1| (U40378) orc1+ protein
[Schizosaccharomyces pombe] >gi|4007803|emb|CAA22443.1|
(AL034463) origin recognition complex protein, subunit
1. [Schizosaccharomyces pombe]
Length = 707
Score = 96.0 bits (235), Expect = 7e-19
Identities = 98/396 (24%), Positives = 171/396 (42%), Gaps = 38/396 (9%)
Query: 37 KNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTE 96
K + +L + P L R + + L ++ ET + +++ G GTGKT TV V
Sbjct: 324 KARAMLHVASVPSTLQCRDNEFSTIFSNLESAIEEETGACLYISGTPGTGKTATVHEVIW 383
Query: 97 ELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWP--TDEVYAK 154
L+++S++ +P + CEI N + + + + W T E
Sbjct: 384 NLQELSREGQLPE---FSFCEI------------NGMRVTSANQAYSILWESLTGERVTP 428
Query: 155 LKQVIDMKERFV---------IIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGI 205
+ + + RF ++++DE+D+LV + +VLY+ + L +++ V+ +
Sbjct: 429 IHAMDLLDNRFTHASPNRSSCVVLMDELDQLVTHN-QKVLYNFFNWPS-LPHSRLIVVAV 486
Query: 206 SNDLKFKE-YLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCA 264
+N + E L R+ S L V F PY QL+ I+ R E V I A
Sbjct: 487 ANTMDLPERILSNRISSRLGLSRVPFEPYTHTQLEIIIAARLEAVRDDDVFSSDAIRFAA 546
Query: 265 ALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQS 324
A GDAR+ALD+ R A E+AE + KVT + +A ++ +++V++ L
Sbjct: 547 RKVAAVSGDARRALDICRRASELAENKN-GKVTPGLIHQAISEMTASPLQKVLRNLSFMQ 605
Query: 325 KVLLYAIV-LLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGII-- 381
KV L AIV + +G + EV L + P + + +LI G +
Sbjct: 606 KVFLCAIVNRMRRSGFAESYVYEVLEEAERLLRVM-TTPDAEAKFGELILRRPEFGYVLS 664
Query: 382 ----NAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYD 413
N + + + R +RL + +I+ FR D
Sbjct: 665 SLSENGVLYLENKSSRNARVRLAIADDEIKLAFRGD 700
>gb|AAB38247.1| (U43392) origin recognition protein Orc1+p [Schizosaccharomyces
pombe]
Length = 544
Score = 96.0 bits (235), Expect = 7e-19
Identities = 98/396 (24%), Positives = 171/396 (42%), Gaps = 38/396 (9%)
Query: 37 KNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTE 96
K + +L + P L R + + L ++ ET + +++ G GTGKT TV V
Sbjct: 161 KARAMLHVASVPSTLQCRDNEFSTIFSNLESAIEEETGACLYISGTPGTGKTATVHEVIW 220
Query: 97 ELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWP--TDEVYAK 154
L+++S++ +P + CEI N + + + + W T E
Sbjct: 221 NLQELSREGQLPE---FSFCEI------------NGMRVTSANQAYSILWESLTGERVTP 265
Query: 155 LKQVIDMKERFV---------IIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGI 205
+ + + RF ++++DE+D+LV + +VLY+ + L +++ V+ +
Sbjct: 266 IHAMDLLDNRFTHASPNRSSCVVLMDELDQLVTHN-QKVLYNFFNWPS-LPHSRLIVVAV 323
Query: 206 SNDLKFKE-YLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCA 264
+N + E L R+ S L V F PY QL+ I+ R E V I A
Sbjct: 324 ANTMDLPERILSNRISSRLGLSRVPFEPYTHTQLEIIIAARLEAVRDDDVFSSDAIRFAA 383
Query: 265 ALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQS 324
A GDAR+ALD+ R A E+AE + KVT + +A ++ +++V++ L
Sbjct: 384 RKVAAVSGDARRALDICRRASELAENKN-GKVTPGLIHQAISEMTASPLQKVLRNLSFMQ 442
Query: 325 KVLLYAIV-LLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGII-- 381
KV L AIV + +G + EV L + P + + +LI G +
Sbjct: 443 KVFLCAIVNRMRRSGFAESYVYEVLEEAERLLRVM-TTPDAEAKFGELILRRPEFGYVLS 501
Query: 382 ----NAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYD 413
N + + + R +RL + +I+ FR D
Sbjct: 502 SLSENGVLYLENKSSRNARVRLAIADDEIKLAFRGD 537
>gb|AAF66067.1|AF254572_1 (AF254572) origin recognition complex subunit 1 [Cricetulus
griseus]
Length = 850
Score = 95.2 bits (233), Expect = 1e-18
Identities = 98/370 (26%), Positives = 162/370 (43%), Gaps = 21/370 (5%)
Query: 41 VLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKK 100
+L S P LP R ++ + + + L T +++ G GTGKT TV V L++
Sbjct: 483 MLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTATVNEVIRCLQQ 542
Query: 101 VSQKYNI-PVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVI 159
+Q ++ P E + +N + ++V I+ + ++ AK
Sbjct: 543 AAQTNDVPPFEYVDVNGMKLTEPHQVYVQILQKLTGQKA-----TANHAAQLLAKRFCSQ 597
Query: 160 DMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YLDPR 218
++ ++++DE+D L+ S +V+Y+L T K A++ V+ I+N + E + R
Sbjct: 598 GSQQETTVLLVDELD-LLWTSKQDVMYNLFDWPTH-KGARLIVLAIANTMDLPERIMMNR 655
Query: 219 VLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKAL 278
V S L + F PY NQLK+IL R + + E+ I L A A GDAR+ L
Sbjct: 656 VSSRLGLTRMSFQPYSHNQLKEILVSRLK---HLKAFEDDAIQLVARKVAALSGDARRCL 712
Query: 279 DLLRVAGEIAE-----REGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVL 333
D+ R A EI E VT H+ A +++ IK L + L AI+
Sbjct: 713 DICRRATEICELSHNHGNSLGPVTVSHLMEAIDEMFSSSYITAIKNCSLLEQGFLRAIIA 772
Query: 334 -LDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYG 392
+G A ++YS + LC +E L +S+ + LG +V R
Sbjct: 773 EFRRSGLEEATFQQIYSQHVALCR---MEGLPYPTMSETMAVCSNLGSCRLLLVEPSRND 829
Query: 393 RTKEIRLNVT 402
+RLNV+
Sbjct: 830 LLLRVRLNVS 839
>gb|AAC60033.1| (U67190) origin recognition complex protein 1 [Xenopus laevis]
Length = 886
Score = 91.7 bits (224), Expect = 1e-17
Identities = 99/371 (26%), Positives = 161/371 (42%), Gaps = 26/371 (7%)
Query: 42 LRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKV 101
L S P+ LP R ++ + + + L T +++ G GTGKT TV V L++
Sbjct: 521 LHVSAVPESLPCREQEYQDVYNFVESKLLDGTGGCMYISGVPGTGKTATVHEVIRSLQES 580
Query: 102 SQKYNIPV-EVIYIN-CEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVI 159
+++ +P+ I IN ++ D H V K TG + D A L++
Sbjct: 581 AEEEELPMFHYIEINGMKLTDPHQA----YVQILKLLTGQKA-----TADHAAALLEKRF 631
Query: 160 D---MKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YL 215
K+ ++++DE+D L + V+YSL T K+AK+ V+ I+N + E +
Sbjct: 632 STPASKKETTVLLVDELDLLWTRK-QNVMYSLFDWPTR-KQAKLIVLAIANTMDLPERIM 689
Query: 216 DPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDAR 275
RV S L + F PY QL+ I+T R + ++ I L A A GDAR
Sbjct: 690 MNRVASRLGLTRMSFQPYTHKQLQQIITSRLN---HIKAFDDDAIQLVARKVAALSGDAR 746
Query: 276 KALDLLRVAGEIAE----REGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAI 331
+ LD+ R A EI E +S V HV A E++ I+ L + L A+
Sbjct: 747 RCLDICRRATEICEFSHSMADSSLVKMSHVIEALEEMFSSPYVTAIRNSSLMEQTFLRAV 806
Query: 332 VLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRY 391
+ L T + +YR+ +E L ++S+ + LG +V R
Sbjct: 807 IAEFRRSGLEEATFQ--QIYRQHVALCRIEGLQPPQMSETMAVCHRLGASRLLLVESSRN 864
Query: 392 GRTKEIRLNVT 402
+R+NV+
Sbjct: 865 DLHLRVRINVS 875
>sp|O16810|ORC1_DROME ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (DMORC1)
>gi|2576416|gb|AAC47802.1| (AF017647) origin recognition
complex subunit 1 [Drosophila melanogaster]
Length = 924
Score = 91.3 bits (223), Expect = 2e-17
Identities = 85/298 (28%), Positives = 136/298 (45%), Gaps = 18/298 (6%)
Query: 39 KEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEEL 98
+E L S PK LP R + E + L ++ + ++V G GTGKT TV V L
Sbjct: 556 REQLHVSVVPKSLPCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTL 615
Query: 99 KKVSQKYNIPV-EVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQ 157
++++++ +P E + IN + + I +K TG V W + +
Sbjct: 616 QRMAKQNELPAFEYLEINGMRLTEPRQAYVQI---YKQLTG---KTVSWEQAHALLEKRF 669
Query: 158 VIDMKERF-VIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YL 215
R ++++DE+D L + D V+Y+L T+ AK+ V+ I+N + E L
Sbjct: 670 TTPAPRRVTTVLLVDELDILCNRRQD-VVYNLLDWPTK-SAAKLVVVTIANTMDLPERLL 727
Query: 216 DPRVLSSLSEEEVVFPPYDANQLKDILTQR--AEEAFYPGVLEEGVIPLCAALAAREHGD 273
+V S L + F PY QL++I+T R E F + + L A A GD
Sbjct: 728 MGKVTSRLGLTRLTFQPYSHKQLQEIVTARLGGSETF-----KGEAVQLVARKVAAVSGD 782
Query: 274 ARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAI 331
AR+ALD+ R A EIA+ VT HV +A ++ + I+ ++ L AI
Sbjct: 783 ARRALDICRRATEIADTAAVKCVTMLHVQQALAEMIASAKVQAIRNCSRMEQIFLQAI 840
>gb|AAF59236.1| (AE003840) Orc1 gene product [Drosophila melanogaster]
Length = 924
Score = 91.3 bits (223), Expect = 2e-17
Identities = 85/298 (28%), Positives = 136/298 (45%), Gaps = 18/298 (6%)
Query: 39 KEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEEL 98
+E L S PK LP R + E + L ++ + ++V G GTGKT TV V L
Sbjct: 556 REQLHVSVVPKSLPCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTL 615
Query: 99 KKVSQKYNIPV-EVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQ 157
++++++ +P E + IN + + I +K TG V W + +
Sbjct: 616 QRMAKQNELPAFEYLEINGMRLTEPRQAYVQI---YKQLTG---KTVSWEQAHALLEKRF 669
Query: 158 VIDMKERF-VIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YL 215
R ++++DE+D L + D V+Y+L T+ AK+ V+ I+N + E L
Sbjct: 670 TTPAPRRVTTVLLVDELDILCNRRQD-VVYNLLDWPTK-SAAKLVVVTIANTMDLPERLL 727
Query: 216 DPRVLSSLSEEEVVFPPYDANQLKDILTQR--AEEAFYPGVLEEGVIPLCAALAAREHGD 273
+V S L + F PY QL++I+T R E F + + L A A GD
Sbjct: 728 MGKVTSRLGLTRLTFQPYSHKQLQEIVTARLGGSETF-----KGEAVQLVARKVAAVSGD 782
Query: 274 ARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAI 331
AR+ALD+ R A EIA+ VT HV +A ++ + I+ ++ L AI
Sbjct: 783 ARRALDICRRATEIADTAAVKCVTMLHVQQALAEMIASAKVQAIRNCSRMEQIFLQAI 840
>sp|P41411|CC18_SCHPO CELL DIVISION CONTROL PROTEIN 18 >gi|539072|pir||A40726 cell
division control protein CDC18+ - fission yeast
(Schizosaccharomyces pombe) >gi|7490208|pir||T39435 cell
division control protein 18 - fission yeast
(Schizosaccharomyces pombe) >gi|311174|gb|AAA02871.1|
(L16793) cell division cycle protein
[Schizosaccharomyces pombe] >gi|3006165|emb|CAA18425.1|
(AL022305) cell division control protein 18
[Schizosaccharomyces pombe]
Length = 577
Score = 90.1 bits (220), Expect = 4e-17
Identities = 102/402 (25%), Positives = 167/402 (41%), Gaps = 60/402 (14%)
Query: 42 LRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKV 101
LR SY + R + + L ++V G GTGKTV + V + +
Sbjct: 160 LRKSYRSAGVVGRENEKSIVESFFRQHLDANAGGALYVSGAPGTGKTVLLHNVLDHVVSD 219
Query: 102 SQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVP--LVGWPTDEVYAKLKQVI 159
K N V YINC ++ + I + E +E + + E+ + Q
Sbjct: 220 YPKVN----VCYINCMTINEPKAIFEKIHSKIVKEEILENEDHHINFQC-ELESHFTQSA 274
Query: 160 DMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRV 219
+ VIIVLDE+D L+ + +VLY+L + +++ ++GI+N L + PR+
Sbjct: 275 NELYNPVIIVLDEMDHLIARE-QQVLYTLFEWPSR-PTSRLILVGIANALDMTDRFLPRL 332
Query: 220 LSS-LSEEEVVFPPYDANQLKDILTQRAEEA---------FYP----------------- 252
+ ++ + + F PY A ++ I+ R + A F P
Sbjct: 333 RTKHITPKLLSFTPYTAQEISTIIKARLKTAATTSEKNNPFTPIKSISEVSDDSINVVSQ 392
Query: 253 -----GVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGAS------------K 295
+ I LCA A GD RKALD+ R A E+AERE + +
Sbjct: 393 HADETPFIHPAAIELCARKVAASSGDLRKALDICRHAIELAEREWKAQHDNTLSSVDIPR 452
Query: 296 VTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELC 355
+ HV RA + Q +K L LQ K +L +V+ ++ + +V+ Y LC
Sbjct: 453 ASIAHVVRATSAMSQSASAR-LKNLGLQQKAILCTLVVCEKTS---LSVADVFEKYSSLC 508
Query: 356 -EYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKE 396
+ PLT D+ N L+ L II + +K R G+ ++
Sbjct: 509 LRDRLIYPLTSSEFCDVANSLETLAIIRLR--TKQRNGKPQD 548
>gi|4758850 origin recognition complex, subunit 1 (yeast homolog)-like; Origin
recognition complex, subunit 1, S. cerevisiae,
homolog-like [Homo sapiens]
>gi|2498705|sp|Q13415|ORC1_HUMAN ORIGIN RECOGNITION
COMPLEX SUBUNIT 1 (REPLICATION CONTROL PROTEIN 1)
>gi|1113101|gb|AAC50325.1| (U40152) HsORC1 [Homo
sapiens]
Length = 861
Score = 88.2 bits (215), Expect = 2e-16
Identities = 95/369 (25%), Positives = 159/369 (42%), Gaps = 21/369 (5%)
Query: 42 LRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKV 101
L S P+ LP R ++ + + + L T +++ G GTGKT TV V L++
Sbjct: 495 LHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQA 554
Query: 102 SQKYNI-PVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVID 160
+Q ++ P + I +N + ++V +I+ + E+ AK
Sbjct: 555 AQANDVPPFQYIEVNGMKLTEPHQVYVHILQKLTGQKA-----TANHAAELLAKQFCTRG 609
Query: 161 MKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YLDPRV 219
+ ++++DE+D L D ++Y+L T K A++ V+ I+N + E + RV
Sbjct: 610 SPQETTVLLVDELDLLWTHKQD-IMYNLFDWPTH-KEARLVVLAIANTMDLPERIMMNRV 667
Query: 220 LSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALD 279
S L + F PY +QL+ IL R + + E+ I L A A GDAR+ LD
Sbjct: 668 SSRLGLTRMCFQPYTYSQLQQILRSRLK---HLKAFEDDAIQLVARKVAALSGDARRCLD 724
Query: 280 LLRVAGEIAE-----REGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVL- 333
+ R A EI E + VT H A +++ IK + + L AI+
Sbjct: 725 ICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAE 784
Query: 334 LDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGR 393
+G A ++YS + LC +E L +S+ + LG +V R
Sbjct: 785 FRRSGLEEATFQQIYSQHVALCR---MEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDL 841
Query: 394 TKEIRLNVT 402
+RLNV+
Sbjct: 842 LLRVRLNVS 850
>pir||G02329 replication control protein 1 - human >gi|1171204|gb|AAA86260.1|
(U43416) replication control protein 1 [Homo sapiens]
Length = 861
Score = 87.8 bits (214), Expect = 2e-16
Identities = 95/369 (25%), Positives = 158/369 (42%), Gaps = 21/369 (5%)
Query: 42 LRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKV 101
L S P+ LP R ++ + + + L T +++ G GTGKT TV V L++
Sbjct: 495 LHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQA 554
Query: 102 SQKYNI-PVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVID 160
+Q ++ P + I +N + ++V I+ + E+ AK
Sbjct: 555 AQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKA-----TANHAAELLAKQFCTRG 609
Query: 161 MKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YLDPRV 219
+ ++++DE+D L D ++Y+L T K A++ V+ I+N + E + RV
Sbjct: 610 SPQETTVLLVDELDLLWTHKQD-IMYNLFDWPTH-KEARLVVLAIANTMDLPERIMMNRV 667
Query: 220 LSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALD 279
S L + F PY +QL+ IL R + + E+ I L A A GDAR+ LD
Sbjct: 668 SSRLGLTRMCFQPYTYSQLQQILRSRLK---HLKAFEDDAIQLVARKVAALSGDARRCLD 724
Query: 280 LLRVAGEIAE-----REGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVL- 333
+ R A EI E + VT H A +++ IK + + L AI+
Sbjct: 725 ICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAE 784
Query: 334 LDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGR 393
+G A ++YS + LC +E L +S+ + LG +V R
Sbjct: 785 FRRSGLEEATFQQIYSQHVALCR---MEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDL 841
Query: 394 TKEIRLNVT 402
+RLNV+
Sbjct: 842 LLRVRLNVS 850
>gi|11422006 origin recognition complex, subunit 1 (yeast homolog)-like [Homo
sapiens]
Length = 502
Score = 87.4 bits (213), Expect = 3e-16
Identities = 94/369 (25%), Positives = 159/369 (42%), Gaps = 21/369 (5%)
Query: 42 LRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKV 101
L S P+ LP R ++ + + + L T +++ G GTGKT TV V L++
Sbjct: 136 LHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQA 195
Query: 102 SQKYNI-PVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVID 160
+Q ++ P + I +N + ++V +++ + E+ AK
Sbjct: 196 AQANDVPPFQYIEVNGMKLTEPHQVYVHLMQKLTGQKA-----TANHAAELLAKQFCTRG 250
Query: 161 MKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YLDPRV 219
+ ++++DE+D L D ++Y+L T K A++ V+ I+N + E + RV
Sbjct: 251 SPQETTVLLVDELDLLWTHKQD-IMYNLFDWPTH-KEARLVVLAIANTMDLPERIMMNRV 308
Query: 220 LSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALD 279
S L + F PY +QL+ IL R + + E+ I L A A GDAR+ LD
Sbjct: 309 SSRLGLTRMCFQPYTYSQLQQILRSRLK---HLKAFEDDAIQLVARKVAALSGDARRCLD 365
Query: 280 LLRVAGEIAE-----REGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVL- 333
+ R A EI E + VT H A +++ IK + + L AI+
Sbjct: 366 ICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAE 425
Query: 334 LDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGR 393
+G A ++YS + LC +E L +S+ + LG +V R
Sbjct: 426 FRRSGLEEATFQQIYSQHVALCR---MEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDL 482
Query: 394 TKEIRLNVT 402
+RLNV+
Sbjct: 483 LLRVRLNVS 491
>gi|6754944 origin recognition complex, subunit 1 homolog (S. cerevisiae);
origin of replication 1 homolog (S. cerevisiae) [Mus
musculus] >gi|4034785|emb|CAA05890.1| (AJ003133)
ORC1-related protein [Mus musculus]
Length = 840
Score = 87.0 bits (212), Expect = 4e-16
Identities = 99/369 (26%), Positives = 160/369 (42%), Gaps = 21/369 (5%)
Query: 42 LRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKV 101
L S P LP R ++ + + + L T +++ G GTGKT TV V L++
Sbjct: 474 LHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTATVHEVIRCLQQA 533
Query: 102 SQKYNI-PVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVID 160
++ ++ P + + +N + ++V I+ K TG + E+ AK
Sbjct: 534 AETDDVPPFQYVEVNGMKLTEPHQVYVQIL---KKLTGQKA--TANHAAELLAKQFCGQG 588
Query: 161 MKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKE-YLDPRV 219
++ ++++DE+D L D V+Y+L T K A + V+ I+N + E + RV
Sbjct: 589 SQKETTVLLVDELDLLWTHKQD-VMYNLFDWPTH-KGAHLIVLTIANTMDLPERIMMNRV 646
Query: 220 LSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALD 279
S L + F PY +QLK IL R E+ I L A A GDAR+ LD
Sbjct: 647 SSRLGLTRMSFQPYSHSQLKQILVSRLRNL---RAFEDDAIQLVARKVAALSGDARRCLD 703
Query: 280 LLRVAGEIAE-----REGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVL- 333
+ R A EI E + S VT H+ A +++ IK + + L AI+
Sbjct: 704 ICRRATEICELSHLRGDSLSLVTVAHLMEAIDEMFSSSYITAIKNSSVVEQSFLRAIIAE 763
Query: 334 LDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGR 393
+G A ++YS + LC +E L +S+ + LG +V R
Sbjct: 764 FRRSGLEEATFQQIYSQHVALCR---MEGLPYPTMSETMAVCSRLGSCRLLLVEPSRNDL 820
Query: 394 TKEIRLNVT 402
+RLNV+
Sbjct: 821 LLRVRLNVS 829
>emb|CAC11593.1| (AL445064) cell division control protein 6 related protein
[Thermoplasma acidophilum]
Length = 347
Score = 84.7 bits (206), Expect = 2e-15
Identities = 88/370 (23%), Positives = 166/370 (44%), Gaps = 42/370 (11%)
Query: 54 RHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIY 113
R +IE + + ++ K +N+ +YG +GTGKTVT++++ E++ +V+Y
Sbjct: 3 RDGEIERIMETVIKPTKNGITTNLILYGDSGTGKTVTMRYLAREIR--------DPQVVY 54
Query: 114 INCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEI 173
+N YR + N++ F + GI VP ++ +++ ++ + + VI+V+DE
Sbjct: 55 VNA----IAYRYVKNVLIDFLSKFGIIVPERS-SYASLFTRIEGLLRNQGKNVILVIDEA 109
Query: 174 DKLVKKSGDEVLYSLTRINTELKRAKVSV-IGISNDLKFKEYLDPRVLSSLS-------E 225
++K D + Y L R+K S + IS E DP +L
Sbjct: 110 ANILKGDYDGLYY--------LFRSKDSFDVNISTIFVVME--DPAILFDAKIRKSYGIF 159
Query: 226 EEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAG 285
E+ F Y ++ I+ RA ++ +E V+ A ++A E+G AR +D+L A
Sbjct: 160 SEIKFRRYTKGEIYQIVMNRAVQSLTGEGYDEDVLDYIAEVSA-EYGSARVGIDILAKAA 218
Query: 286 EIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTG 345
IAE + K++ V A+ I + E + ++ + ++L +I +
Sbjct: 219 HIAEYRRSPKISFDDVRAARSMISPFVTESKLASMDYEDLMVLLSICRCLS----ASRFT 274
Query: 346 EVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTK------EIRL 399
+V + R L + + D I L+ GII++ + +GR K +I +
Sbjct: 275 DVDCISRNLSVISEQYGKKDINLYDRIKRLENNGIISSSIEGQGRGEGVKKVISIYDIPV 334
Query: 400 NVTPYKIRNV 409
+V KI N+
Sbjct: 335 SVLTEKIENL 344
>dbj|BAA89785.1| (AB037135) origin recognition complex 1 [Oryza sativa]
Length = 779
Score = 82.7 bits (201), Expect = 7e-15
Identities = 84/324 (25%), Positives = 151/324 (45%), Gaps = 48/324 (14%)
Query: 37 KNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSN--IFVYGKTGTGKTVTVKFV 94
K K L + PK LP R +++E ++ + + + ++++G GTGKT++V V
Sbjct: 420 KAKATLLLANLPKSLPCRDKEMEEISAFVKDAICNDQCIGRCLYIHGVPGTGKTMSVLAV 479
Query: 95 TEELKKVSQKYNI-PVEVIYIN---CEIVDTHYRVLANIVNHFKDETGIEVPLVGWPT-- 148
L+ N+ P I IN + Y+V+ ++ + VGW
Sbjct: 480 MRRLRSELDSGNLRPYSFIEINGLKLASPENIYKVIYEQLSGHR---------VGWKKAL 530
Query: 149 ---DEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSL----TRINTELKRAKVS 201
E ++ ++ + +I+++DE+D L+ ++ VLY++ TR N+ L
Sbjct: 531 HYLTEHFSGGTKIGKQANQPIILLIDELDLLLTRN-QSVLYNILDWPTRPNSNLV----- 584
Query: 202 VIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAE--EAFYPGVLEEGV 259
VIGI+N + E L R+ S + + + F PY+ QL++I+T R + +AF E+
Sbjct: 585 VIGIANTMDLPEKLLLRISSRMGIQRLCFGPYNYRQLQEIITSRLKGIDAF-----EDQA 639
Query: 260 IPLCAALAAREHGDARKALDLLRVAGEIAE-----------REGASKVTEKHVWRAQEKI 308
I + A GDAR+AL++ R A E A+ G + V + A +++
Sbjct: 640 IEFASRKVAAMSGDARRALEICRRAAEFADYRVKQSGHTSVNRGKNVVCMGDIEAAIQEV 699
Query: 309 EQDMMEEVIKTLPLQSKVLLYAIV 332
Q +V+K P K++L A+V
Sbjct: 700 FQAPHIQVMKNCPKFGKIILVAMV 723
>pir||T46606 cell cycle control protein cdc6 [imported] - yeast (Candida
albicans) >gi|4688625|emb|CAB41412.1| (AJ238026) CDC6
protein [Candida albicans]
Length = 481
Score = 80.4 bits (195), Expect = 4e-14
Identities = 68/285 (23%), Positives = 138/285 (47%), Gaps = 27/285 (9%)
Query: 31 KARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVT 90
+A+ +F+ + HS L R ++ + + + ++ + +++++ G GTGKT
Sbjct: 76 QAKALFQRGSNVSHS-NDYFLTSREKEAKYITDFVANSIQQKISNSLYISGPPGTGKTAQ 134
Query: 91 VKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDE 150
V+ + + ++ S+ + V+ INC ++ ++ I ++ I D+
Sbjct: 135 VQLILQPYQQNSR-----IRVVKINCMTLNNPEQIYHEIYCKIMNKLSISFHKRK-TCDD 188
Query: 151 VYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINT----ELKRAKVSVIGIS 206
+ + + VI++LDE+D L+ S +VL+ L ++ + + K+ +IGIS
Sbjct: 189 FMTLMNDNENQQFDSVIVLLDELDSLIT-SDQQVLFQLFKMASINCIPQTKIKLVLIGIS 247
Query: 207 NDLKFKEYLDPRVL-SSLSEEEVVFPPYDANQLKDILTQRA----EEAFYPGVLEEGVIP 261
N L PR++ +++ + + F PY+A+Q+K I+ R +E F+PG ++
Sbjct: 248 NTLDLNSKFLPRLVRNNIQLDNLQFLPYNADQIKSIIMNRLSNLKQEIFHPGAIQ----- 302
Query: 262 LCAALAAREHGDARKALDLLRVAGEIAER-----EGASKVTEKHV 301
C +A GD RKA D+ + E+ ER + +KV +HV
Sbjct: 303 FCCKKSASISGDLRKAFDICYKSIELVERSCQGTDTINKVMIQHV 347
>gb|AAB37629.1| (U80437) similar to several cell division control proteins
[Caenorhabditis elegans]
Length = 518
Score = 78.0 bits (189), Expect = 2e-13
Identities = 82/333 (24%), Positives = 143/333 (42%), Gaps = 33/333 (9%)
Query: 51 LPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVE 110
L R E+ ++L ++ + T +I+V G+ GTGKT T V + L K V
Sbjct: 172 LKGRREEFDSLKLWIMKSKETNTSLSIYVSGQPGTGKTATTMRVLKSLGK-------SVR 224
Query: 111 VIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAK-LKQVIDMKERFVIIV 169
+NC +T + I + L G P +E++ K +KQ + +++V
Sbjct: 225 SCIVNCASTNTKSALFKTIFE--------SLDLDGKPNEEIFEKHVKQF----KTPLVLV 272
Query: 170 LDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVV 229
LDEID L + + LY+ + L R K+ ++GI+N + E L P+++ + + +V
Sbjct: 273 LDEIDHLANRK-NAALYAAFQWPETLSR-KIIILGIANSIDLTERLLPKLMLAKPPKRLV 330
Query: 230 FPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAE 289
F PY + + +IL + + ++ I L A A GD R AL + +
Sbjct: 331 FEPYTKDDIVEILNDKMKNE--ETSIDAKAIELTARKVAAMSGDLRTALHIFKQQKSRMI 388
Query: 290 REGASKVTEKHVWRAQEKIEQDMMEEVIKT------LPLQSKVLLYAIVLLDENGDLPAN 343
+ SKV V +E + ++ V + LPLQ ++LL + L N +
Sbjct: 389 PDD-SKVPGTPVNGCREVL--GIINNVYSSPLARARLPLQPRILLAVSLTLSANKKCTFD 445
Query: 344 TGEVYSVYRELCEYLDLEPLTQRRISDLINELD 376
+ Y + CE L + L + L+
Sbjct: 446 RNSLLRAYYKACEALRMPALDDDELHSAFQTLE 478
>gi|10803686 ORF H1602 [Halobacterium sp. NRC-1] >gi|7484016|pir||T08356 cell
division control protein 6 truncated homolog H1602 -
Halobacterium sp. (strain NRC-1) plasmid pNRC100
>gi|2822417|gb|AAC82923.1| (AF016485) ORF H1602
[Halobacterium sp. NRC-1]
Length = 153
Score = 78.0 bits (189), Expect = 2e-13
Identities = 45/142 (31%), Positives = 77/142 (53%), Gaps = 9/142 (6%)
Query: 35 IFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFV 94
+ ++ VLR + P+++ HR ++ L+ +L P+ GE V G +GTGKT +FV
Sbjct: 13 MIRDARVLRAGFVPREVEHRDAEVNHLSSVLEPITNGEPADTAIVTGPSGTGKTCISQFV 72
Query: 95 TEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAK 154
TE L++ + VE Y+NC T +R L I++ F + I++ P DE+ +
Sbjct: 73 TERLREEV----LNVEATYVNCWRNYTRFRTLYQILDDFGET--IDIHRQSTPHDELIDR 126
Query: 155 LKQVIDMKERFVIIVLDEIDKL 176
L+Q + +I+LDE+D+L
Sbjct: 127 LQQYDGPR---TVIILDEVDQL 145
>gb|AAC35241.1| (AC005496) putative CDC6 protein [Arabidopsis thaliana]
Length = 535
Score = 76.9 bits (186), Expect = 4e-13
Identities = 78/382 (20%), Positives = 171/382 (44%), Gaps = 29/382 (7%)
Query: 39 KEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEEL 98
KE L S P + R ++ + + + ++ + ++++ G GTGK+++++ V +
Sbjct: 117 KEALHVSKAPSTVVCREDEQRRVFEFVKGCMEQKKAGSLYICGCPGTGKSLSMEKVRLQA 176
Query: 99 KKVSQKYNIPV-EVIYINCEIVDTHYRVLANIVNHF---KDETGIEVPLVGWPTDEVYAK 154
++ +++ + E + +NC + + + I+ ++ K G PL ++++
Sbjct: 177 EEWAKQAGLHCPETVSVNCTSLTKSTDIFSKILGNYESGKKANGSFSPLQ--QLQRLFSQ 234
Query: 155 LKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEY 214
+Q + + ++I+ DE+D L+ + VL+ L + T L ++ +IG++N + +
Sbjct: 235 KQQ--QSRSKMMLIIADEMDYLITRDRG-VLHELFMLTT-LPLSRCILIGVANAIDLADR 290
Query: 215 LDPRVLSSLSEEEVV-FPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGD 273
P++ S + VV F Y +Q+ IL +R + + + +CA + GD
Sbjct: 291 FLPKLKSLNCKPLVVTFRAYSKDQILRILQERLVALPFVA-FQSNALEICARKVSAASGD 349
Query: 274 ARKALDLLRVAGEIAEREGASKVTEK--------------HVWRAQEKIEQDMMEEVIKT 319
RKAL + R A EI E E + ++ H+ A K + + + I++
Sbjct: 350 MRKALCVCRSALEILEIEVRGSIDQEPKGPVPECQVVKMDHMIAALSKTFKSPIVDTIQS 409
Query: 320 LPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLG 379
LP ++++ + E+ +Y E+C+ + P S++ L+ G
Sbjct: 410 LPQHQQIIVCSAAKAFRGSKKDRTIAELNKLYLEICKSSMITPAGITEFSNMCTVLNDQG 469
Query: 380 IINAKVVSKGRYGRTKEIRLNV 401
I+ +S R + K + L V
Sbjct: 470 ILK---LSLARDDKLKRVSLRV 488
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.137 0.381
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 156687222
Number of Sequences: 2977
Number of extensions: 6640909
Number of successful extensions: 21967
Number of sequences better than 1.0e-10: 51
Number of HSP's better than 0.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 21829
Number of HSP's gapped (non-prelim): 53
length of query: 432
length of database: 189,106,746
effective HSP length: 59
effective length of query: 373
effective length of database: 153,796,013
effective search space: 57365912849
effective search space used: 57365912849
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)