BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2273 (moaA) DE:molybdenum cofactor biosynthesis protein
(moaA)
(306 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75198 molybdopterin biosynthesis protein moaA PAB2273 - Py... 617 e-176
sp|O57854|MOAA_PYRHO PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS P... 580 e-165
emb|CAC11585.1| (AL445064) molybdopterin biosynthesis protein mo... 265 7e-70
sp|Q58234|MOAA_METJA PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS P... 260 2e-68
pir||H69073 molybdopterin biosynthesis protein moaA - Methanobac... 259 2e-68
sp|O27593|MOAA_METTH PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS P... 259 2e-68
gi|11499588 molybdenum cofactor biosynthesis protein (moaA) [Arc... 252 5e-66
gb|AAK40692.1| Molybdenum cofactor biosynthesis protein A (moaA)... 218 6e-56
sp|Q9YEV3|MOAA_AERPE PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS P... 199 3e-50
sp|Q9WX96|MOAA_CLOPE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 181 1e-44
sp|Q39055|CNX2_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX2 PROTEIN (MO... 176 4e-43
pir||A81434 molybdenum cofactor biosynthesis protein A Cj0161c [... 171 1e-41
pir||T22465 hypothetical protein F49H6.5 - Caenorhabditis elegan... 167 1e-40
gb|AAG18718.1| (AE004976) molybdenum cofactor biosynthesis prote... 167 1e-40
sp|Q20624|YL71_CAEEL HYPOTHETICAL 64.9 KD PROTEIN F49E2.1 IN CHR... 166 3e-40
emb|CAB59437.1| (AL132644) molybdenum cofactor biosynthesis prot... 165 7e-40
gb|AAF50108.1| (AE003546) Mocs1 gene product [Drosophila melanog... 163 3e-39
sp|O67929|MOAA_AQUAE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 163 3e-39
gb|AAF67855.1|AF214021_1 (AF214021) molybdenum cofactor synthesi... 162 5e-39
emb|CAA11897.1| (AJ224328) MOCS1A protein [Homo sapiens] 162 5e-39
pir||S57490 molybdopterin cofactor synthesis protein - Arthrobac... 161 1e-38
sp|Q44118|MOAA_ARTNI PROBABLE MOLYBDOPTERIN COFACTOR SYNTHESIS P... 161 1e-38
gb|AAB87523.1| (AF034374) molybdenum cofactor biosynthesis prote... 161 1e-38
sp|P39757|MOAA_BACSU MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 160 2e-38
sp|Q9ZIM6|MOAA_STACA MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 157 1e-37
sp|Q9ZL75|MOAA_HELPJ MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 157 2e-37
sp|P56414|MOAA_HELPY MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 151 9e-36
sp|O53881|MOA2_MYCTU MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 150 3e-35
pir||E83457 molybdopterin biosynthetic protein A2 PA1505 [import... 148 6e-35
sp|O05786|MOA1_MYCTU MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 145 7e-34
emb|CAA76291.1| (Y16569) moaA [Mycobacterium tuberculosis] 145 9e-34
dbj|BAB06245.1| (AP001515) molybdopterin cofactor biosynthesis [... 144 1e-33
pir||B83162 molybdopterin biosynthetic protein A1 PA3870 [import... 142 4e-33
sp|Q9X5W3|MOAA_RHOCA MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 141 8e-33
sp|Q56211|MOAA_SYNP7 MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 138 1e-31
sp|Q55369|MOAA_SYNY3 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A ... 137 2e-31
gb|AAB84030.1| (AF027213) molybdopterin cofactor biosynthetic pr... 134 2e-30
sp|P45311|MOAA_HAEIN MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 132 4e-30
sp|P30745|MOAA_ECOLI MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A ... 129 4e-29
emb|CAA75545.1| (Y15252) molybdopterin co-factor synthesis prote... 128 1e-28
pir||F82250 molybdenum cofactor biosynthesis protein A VC1024 [i... 116 4e-25
sp|Q50746|MOAA_METTM PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS P... 99 8e-20
pir||G71040 hypothetical protein PH1615 - Pyrococcus horikoshii ... 85 1e-15
pir||H69210 conserved hypothetical protein MTH831 - Methanobacte... 82 9e-15
pir||B75174 molybdenum cofactor biosynthesis protein A related P... 82 1e-14
gi|11499897 conserved hypothetical protein [Archaeoglobus fulgid... 81 2e-14
sp|Q58036|Y619_METJA HYPOTHETICAL PROTEIN MJ0619 >gi|2128410|pir... 79 6e-14
gb|AAK41845.1| Coenzyme PQQ synthesis protein E (pqqE-3) [Sulfol... 78 1e-13
gb|AAK42035.1| Coenzyme PQQ synthesis protein E (pqqE-4) [Sulfol... 76 7e-13
emb|CAC11421.1| (AL445063) molybdenum cofactor synthesis-step 1 ... 76 7e-13
sp|Q57567|Y103_METJA HYPOTHETICAL PROTEIN MJ0103 >gi|2128126|pir... 73 3e-12
pir||D64400 hypothetical protein MJ0804 - Methanococcus jannaschii 73 6e-12
sp|Q58214|Y804_METJA HYPOTHETICAL PROTEIN MJ0804 >gi|2826326|gb|... 73 6e-12
gi|11498523 pyruvate formate-lyase activating enzyme (act-2) [Ar... 71 2e-11
sp|P71517|PQQE_METEX COENZYME PQQ SYNTHESIS PROTEIN E >gi|216068... 70 3e-11
gi|11499591 heme biosynthesis protein (nirJ-2) [Archaeoglobus fu... 70 4e-11
>pir||E75198 molybdopterin biosynthesis protein moaA PAB2273 - Pyrococcus abyssi
(strain Orsay) >gi|5457545|emb|CAB49036.1| (AJ248283)
molybdenum cofactor biosynthesis protein (moaA)
[Pyrococcus abyssi]
Length = 306
Score = 617 bits (1574), Expect = e-176
Identities = 306/306 (100%), Positives = 306/306 (100%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKV 60
MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKV
Sbjct: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKV 60
Query: 61 KLTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDR 120
KLTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDR
Sbjct: 61 KLTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDR 120
Query: 121 KKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQL 180
KKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQL
Sbjct: 121 KKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQL 180
Query: 181 IEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEVEV 240
IEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEVEV
Sbjct: 181 IEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEVEV 240
Query: 241 VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVLM 300
VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVLM
Sbjct: 241 VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVLM 300
Query: 301 RRPYWT 306
RRPYWT
Sbjct: 301 RRPYWT 306
>sp|O57854|MOAA_PYRHO PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A
>gi|7451234|pir||H71231 molybdopterin biosynthesis
protein moaA - Pyrococcus horikoshii
>gi|3256500|dbj|BAA29183.1| (AP000001) 316aa long
hypothetical molybdenum cofactor biosynthesis protein
[Pyrococcus horikoshii]
Length = 316
Score = 580 bits (1480), Expect = e-165
Identities = 275/306 (89%), Positives = 303/306 (98%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKV 60
MLIDRFGRPVTNLRISLTKECNL+CFYCHREGQLDGER M PEEIERIVR+ASRLGIKKV
Sbjct: 7 MLIDRFGRPVTNLRISLTKECNLSCFYCHREGQLDGERFMTPEEIERIVRVASRLGIKKV 66
Query: 61 KLTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDR 120
KLTGGEPTIRKDI+EIIRR++PYVVDLSLTTNGTT+Y LAE+LKEAGLDRVNISLDTLDR
Sbjct: 67 KLTGGEPTIRKDILEIIRRLKPYVVDLSLTTNGTTMYVLAEKLKEAGLDRVNISLDTLDR 126
Query: 121 KKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQL 180
KKYKMITGF+VLD+VIKGI+KATKLFYPVKLNMVVM+G+NDDEIWD++RFAG+VNAILQL
Sbjct: 127 KKYKMITGFNVLDEVIKGIKKATKLFYPVKLNMVVMKGVNDDEIWDMMRFAGEVNAILQL 186
Query: 181 IEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEVEV 240
IE+EVPREMENSQFFKDFFYPLKPLEE+FEK+AV+++ERRMHRRRKYF+P+DGK+VEVEV
Sbjct: 187 IELEVPREMENSQFFKDFFYPLKPLEEKFEKLAVKVKERRMHRRRKYFIPIDGKIVEVEV 246
Query: 241 VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVLM 300
VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDA+L++IFKRAVL+
Sbjct: 247 VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDADLIEIFKRAVLL 306
Query: 301 RRPYWT 306
RRPYWT
Sbjct: 307 RRPYWT 312
>emb|CAC11585.1| (AL445064) molybdopterin biosynthesis protein moaA related protein
[Thermoplasma acidophilum]
Length = 324
Score = 265 bits (669), Expect = 7e-70
Identities = 132/306 (43%), Positives = 199/306 (64%), Gaps = 6/306 (1%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVK 61
+ DR+GRPV +LRI L CN +CF+CH EG + PEEIER+V+I+ G+ KVK
Sbjct: 3 IYDRYGRPVLSLRIQLNTTCNFSCFFCHMEGTDVNGEELTPEEIERVVKISHEFGVNKVK 62
Query: 62 LTGGEPTIRKDIVEIIRRIRPYVV-DLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDR 120
+TGGEPT+R DI++II RIR ++ ++S+TTNGT L +A++LK+AGLDRVNISL + D
Sbjct: 63 ITGGEPTLRADIIDIIGRIRKHITGNISMTTNGTMLPKIAKDLKKAGLDRVNISLHSPDD 122
Query: 121 KKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQ 179
+++ ITG ++D+V++ + A PVK+N VV++ +N ++I ++ A + NAILQ
Sbjct: 123 ERFHFITGTRMIDRVLEAVRSANDAGLTPVKINFVVLKDLNVNDIPRMLEIAAENNAILQ 182
Query: 180 LIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEVE 239
LIE E RE E+S+ ++ + L P+E + K A+ + +H R +Y + D VV++E
Sbjct: 183 LIEYETDREGESSEEYRRYHISLDPIEAQIRKKAIGVEYNDLHNRPRYLMKNDHGVVKIE 242
Query: 240 VVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVL 299
V+ N FC +CTRLR+T+ G KTCL+R D + P + + L D+F+ AV
Sbjct: 243 FVKPQRNPDFCAHCTRLRITSRGEFKTCLMRSDTNV----PFKGVTDENRLRDLFRIAVS 298
Query: 300 MRRPYW 305
+R PYW
Sbjct: 299 LREPYW 304
>sp|Q58234|MOAA_METJA PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A
>gi|2129127|pir||H64402 molybdopterin biosynthesis
protein moaA - Methanococcus jannaschii
>gi|1591511|gb|AAB98823.1| (U67526) molybdenum cofactor
biosynthesis protein (moaA) [Methanococcus jannaschii]
Length = 298
Score = 260 bits (657), Expect = 2e-68
Identities = 142/305 (46%), Positives = 206/305 (66%), Gaps = 15/305 (4%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQ-LDGERTMKPEEIERIVRIASRLGIKKVKL 62
D+FGR + +LRIS+T +CNL CFYCHREG + +R M PEEI I + +++ G+KK+K+
Sbjct: 3 DKFGREIRSLRISITNKCNLQCFYCHREGHDSNNDRYMTPEEIGIIAKTSTKFGVKKIKI 62
Query: 63 TGGEPTIRKDIVEIIRRIRPY-VVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDRK 121
+GGEP +RKD+ EII I+ + D+SLTTNG L LAE+LK+AGL+RVN+SLDTL+ +
Sbjct: 63 SGGEPLLRKDVCEIIENIKDERIKDISLTTNGILLENLAEKLKDAGLNRVNVSLDTLNPE 122
Query: 122 KYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQL 180
YK IT F +++VI GI+KA + P+K+N + M IN ++ D++ F + AILQ+
Sbjct: 123 LYKKITKFGDVERVINGIKKAIDVSLTPLKVNFLAM-SINIKDLPDIMEFCRDIGAILQI 181
Query: 181 IEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEVEV 240
IE +P + E K ++Y + P+E E ++ A ++ R + RK ++ VDG +E+E
Sbjct: 182 IEF-IPLKEE----LKGYYYNISPIENEIKEKADKVITRNFMQNRKKYI-VDG--LEIEF 233
Query: 241 VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVLM 300
VR M N+ FCM+CTR+RLT DGYLK CLLR D+L+D+L PLR G + L F +
Sbjct: 234 VRPMDNSEFCMHCTRIRLTYDGYLKPCLLRDDNLVDVLTPLRKGEN---LEPYFIECINR 290
Query: 301 RRPYW 305
R PY+
Sbjct: 291 REPYF 295
>pir||H69073 molybdopterin biosynthesis protein moaA - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622671|gb|AAB86024.1| (AE000915) molybdenum
cofactor biosynthesis MoaA [Methanobacterium
thermoautotrophicum]
Length = 316
Score = 259 bits (656), Expect = 2e-68
Identities = 140/306 (45%), Positives = 195/306 (62%), Gaps = 9/306 (2%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVKLT 63
DR GRPV +LR+S+T CN+NC YCHR+G + +IE++ R+AS LG+ K++L+
Sbjct: 16 DRHGRPVMSLRLSITGRCNVNCIYCHRDGMTSSRGELSAADIEKLCRVASDLGVGKIRLS 75
Query: 64 GGEPTIRKDIVEIIRRIRPY-VVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDRKK 122
GGEP IR DIVEI+ RI D+S+TTNGT L + L EAGLDRVN+S DTL+ +
Sbjct: 76 GGEPLIRDDIVEIVERINNIGFRDISITTNGTLLEGYSAALSEAGLDRVNVSFDTLNPET 135
Query: 123 YKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQLI 181
Y+ IT D L++V GI A + PVK+NMV++RG+N E+WD+ F + A+LQ+I
Sbjct: 136 YRFITRKDYLERVKSGITSAVDVGLDPVKINMVILRGVNHHEVWDMFEFCREKGAVLQII 195
Query: 182 EIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERR-MHRRRKYFLPVDGKVVEVEV 240
E+ + E + + + + P+E E ++A IR R+ M R+KY+ +DG E+EV
Sbjct: 196 EL-LKTESCHDDAVERYHCDITPIEAELAEMADRIRTRKFMQDRKKYY--IDGG--EIEV 250
Query: 241 VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVLM 300
VR M NT FC NCTRLR+T DG LK CLLR D+L+D LR L ++F A+
Sbjct: 251 VRPMDNTRFCANCTRLRVTPDGKLKPCLLRNDNLVDTRDALREN-DTGRLRELFFEAIRR 309
Query: 301 RRPYWT 306
R PY+T
Sbjct: 310 RSPYYT 315
>sp|O27593|MOAA_METTH PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A
Length = 305
Score = 259 bits (656), Expect = 2e-68
Identities = 140/306 (45%), Positives = 195/306 (62%), Gaps = 9/306 (2%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVKLT 63
DR GRPV +LR+S+T CN+NC YCHR+G + +IE++ R+AS LG+ K++L+
Sbjct: 5 DRHGRPVMSLRLSITGRCNVNCIYCHRDGMTSSRGELSAADIEKLCRVASDLGVGKIRLS 64
Query: 64 GGEPTIRKDIVEIIRRIRPY-VVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDRKK 122
GGEP IR DIVEI+ RI D+S+TTNGT L + L EAGLDRVN+S DTL+ +
Sbjct: 65 GGEPLIRDDIVEIVERINNIGFRDISITTNGTLLEGYSAALSEAGLDRVNVSFDTLNPET 124
Query: 123 YKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQLI 181
Y+ IT D L++V GI A + PVK+NMV++RG+N E+WD+ F + A+LQ+I
Sbjct: 125 YRFITRKDYLERVKSGITSAVDVGLDPVKINMVILRGVNHHEVWDMFEFCREKGAVLQII 184
Query: 182 EIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERR-MHRRRKYFLPVDGKVVEVEV 240
E+ + E + + + + P+E E ++A IR R+ M R+KY+ +DG E+EV
Sbjct: 185 EL-LKTESCHDDAVERYHCDITPIEAELAEMADRIRTRKFMQDRKKYY--IDGG--EIEV 239
Query: 241 VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVLM 300
VR M NT FC NCTRLR+T DG LK CLLR D+L+D LR L ++F A+
Sbjct: 240 VRPMDNTRFCANCTRLRVTPDGKLKPCLLRNDNLVDTRDALREN-DTGRLRELFFEAIRR 298
Query: 301 RRPYWT 306
R PY+T
Sbjct: 299 RSPYYT 304
>gi|11499588 molybdenum cofactor biosynthesis protein (moaA) [Archaeoglobus
fulgidus] >gi|6685645|sp|O28273|MOAA_ARCFU PUTATIVE
MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A
>gi|7451232|pir||E69500 molybdopterin biosynthesis
protein moaA - Archaeoglobus fulgidus
>gi|2648531|gb|AAB89248.1| (AE000964) molybdenum
cofactor biosynthesis protein (moaA) [Archaeoglobus
fulgidus]
Length = 296
Score = 252 bits (636), Expect = 5e-66
Identities = 137/311 (44%), Positives = 196/311 (62%), Gaps = 23/311 (7%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKV 60
ML D +GR VTNLRI++TK+CNL CFYCH+EG+ + + E I I R LG++K+
Sbjct: 1 MLKDEYGRVVTNLRIAVTKKCNLRCFYCHKEGESNPGEEISAERIVEIARAFKELGVRKL 60
Query: 61 KLTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDR 120
K+TGGEP +RKD+ +II + P ++S+TTNG L AEEL+E GL RVN+SLDTLD
Sbjct: 61 KITGGEPLLRKDLPDIILNL-PEFEEISMTTNGILLEKYAEELRECGLSRVNVSLDTLDA 119
Query: 121 KKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFA-----GKV 174
+KY+ ITG + +V+ GIEKA ++ PVK+NM+V+ G+ND+E+ +L+ F G
Sbjct: 120 EKYRWITGGGEVQKVVNGIEKACEVGLTPVKINMLVLGGVNDNEVDELLEFTNSFNRGNT 179
Query: 175 NAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGK 234
AILQ+IE+ VP F+ +F+ + +EE++ ++A + R R MHRR +YF P
Sbjct: 180 KAILQVIEL-VP-----FPGFEKYFFDISTIEEKYARMATQRRVRAMHRRTQYFTPKG-- 231
Query: 235 VVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIF 294
+E V+ M NT FCM+C R+R+T+DG LK CLLR + + +G EL
Sbjct: 232 --VIEFVKPMDNTAFCMHCNRMRVTSDGKLKPCLLRNETI------TIDGKHGEELARAI 283
Query: 295 KRAVLMRRPYW 305
V R PY+
Sbjct: 284 IETVRKREPYF 294
>gb|AAK40692.1| Molybdenum cofactor biosynthesis protein A (moaA) [Sulfolobus
solfataricus]
Length = 308
Score = 218 bits (550), Expect = 6e-56
Identities = 127/301 (42%), Positives = 185/301 (61%), Gaps = 8/301 (2%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVK 61
+IDRFGRP+ +LRI+LT CN CF+CH EG+ + E+I + ++A + GI VK
Sbjct: 1 MIDRFGRPLEDLRITLTHACNFECFFCHMEGEEGDNYLLSKEDILLVAKVARKFGINSVK 60
Query: 62 LTGGEPTIRKDIVEIIRRIRPY-VVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDR 120
LTGGEPT+R+D+VEI+R ++ D+S+TTNG L LA +LK AGLDR+NISL + R
Sbjct: 61 LTGGEPTLRRDLVEIVRGLKQLGYEDVSMTTNGFLLKDLAHKLKLAGLDRINISLHAVSR 120
Query: 121 KKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQ 179
+K ITG D D+VI+GI+ A + PVKLN VV R N +E + I + + + +
Sbjct: 121 DTFKKITGVDAFDRVIEGIKSAIDVGLVPVKLNFVVNRR-NREEAFKFIELSQNL-GVNE 178
Query: 180 LIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEVE 239
+ IE+ FK+ L+ +EE EKI+++ R+ H R +Y LP G + VE
Sbjct: 179 IHLIELHPVGLGKLAFKE-HDDLREIEEYIEKISIKKLIRKKHFRPRYVLP-SGLI--VE 234
Query: 240 VVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAVL 299
VV+ N +FC C R+RL+ DG LKTCL R D++ID+L L+ S+ ++ RA +
Sbjct: 235 VVKPYANPIFCAGCNRIRLSVDGKLKTCLYREDNVIDVLDILKGEYSEDVKEELLGRAFM 294
Query: 300 M 300
+
Sbjct: 295 I 295
>sp|Q9YEV3|MOAA_AERPE PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A
>gi|7521225|pir||G72743 probable molybdopterin cofactor
biosynthesis protein A APE0478 - Aeropyrum pernix
(strain K1) >gi|5104127|dbj|BAA79443.1| (AP000059) 355aa
long hypothetical molybdopterin cofactor biosynthesis
protein A [Aeropyrum pernix]
Length = 355
Score = 199 bits (501), Expect = 3e-50
Identities = 121/316 (38%), Positives = 174/316 (54%), Gaps = 20/316 (6%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKP---------EEIERIVRI 51
M+ D +GRP+ +LRI++T ECNL+CF+CH EG + M+P E+ + I
Sbjct: 1 MVADAYGRPLKDLRIAVTPECNLDCFFCHMEGATESG-PMRPGSWSPVLSVEDYDIIGEA 59
Query: 52 ASRLGIKKVKLTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRV 111
ASRLG+ KLTGGEP IR D+ +I+ + Y ++S+TTNG L A LK AGL RV
Sbjct: 60 ASRLGVDSFKLTGGEPLIRGDVDKIVAVLARYG-EVSMTTNGILLPLKASSLKRAGLARV 118
Query: 112 NISLDTLDRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFA 171
N+SL ++ + Y+ IT + +KG+E A K VK+NMV++RG+N+ E W L+R A
Sbjct: 119 NVSLHSISEEVYEKITRRRAVKLALKGVEAALKAGLRVKVNMVLLRGLNEGEFWRLLRLA 178
Query: 172 GKVNAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPV 231
+ LQ+IE+ + F P+ +EE +AV + R+H RR Y LP
Sbjct: 179 EDLGFDLQVIEVHPAG--RGRKVLSSFRRPIDVVEERLSSMAVAVETGRLHNRRVYRLP- 235
Query: 232 DGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAE-- 289
V V +V + N VFCM C R+RLT DG L C+ + + L+ G S E
Sbjct: 236 --SGVRVYLVDPVENPVFCMGCYRVRLTWDGRLLPCIYWKGPYPSVAEALKRGGSREEKV 293
Query: 290 --LVDIFKRAVLMRRP 303
++ I A +RRP
Sbjct: 294 WRVMKILLEANALRRP 309
>sp|Q9WX96|MOAA_CLOPE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A
>gi|4589922|dbj|BAA76928.1| (AB017192) molybdenum
cofactor biosynthesis protein A [Clostridium
perfringens]
Length = 323
Score = 181 bits (454), Expect = 1e-44
Identities = 112/300 (37%), Positives = 178/300 (59%), Gaps = 10/300 (3%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQLD---GERTMKPEEIERIVRIASRLGIKKV 60
D++GR + LRISLT +CNL C YC + D ++ M +EI R+V+ + +GIKKV
Sbjct: 3 DKYGREIDYLRISLTDKCNLRCAYCMEKDHNDFIHNDKLMTLDEILRVVKECASIGIKKV 62
Query: 61 KLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTL 118
+LTGGEP +R+ IV++I+ I P + ++ LTTNG L +EL E GL RVNISLDTL
Sbjct: 63 RLTGGEPLVREGIVDLIKNINKIPEIEEICLTTNGILLGDKVKELSENGLKRVNISLDTL 122
Query: 119 DRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAIL 178
++K IT LD+V+ IEK + VK+N V++ N DEI DLI A K L
Sbjct: 123 KEDRFKEITRIGTLDKVLYSIEKCLENNVKVKINTVILEDFNKDEILDLINLAYKNPIDL 182
Query: 179 QLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVEV 238
+ IE+ +P E +F + + ++ +K+ + + R++ KY + ++G ++
Sbjct: 183 RFIEL-MPIG-EGKKFKGVTNSEILEIIKKEKKVLSDGKPLRLNGPAKY-ISIEGFKGKI 239
Query: 239 EVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFKRAV 298
+ +M + FC +C R+R+T +G++K CL + I++ +RNG SD EL +I K+++
Sbjct: 240 GFISAM-SDCFCEDCNRIRVTPEGFMKQCLHWKYG-INLRDKMRNGISDEELREIIKKSI 297
>sp|Q39055|CNX2_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX2 PROTEIN (MOLYBDENUM COFACTOR
BIOSYNTHESIS ENZYME CNX2) >gi|662871|emb|CAA88107.1|
(Z48047) Cnx2 [Arabidopsis thaliana]
>gi|6598535|gb|AAD15381.2| (AC006223) molybdopterin
synthase (CNX2) [Arabidopsis thaliana]
Length = 390
Score = 176 bits (441), Expect = 4e-43
Identities = 121/312 (38%), Positives = 168/312 (53%), Gaps = 18/312 (5%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPE-----EIERIVRIASRL 55
MLID+FGR T LRISLT+ CNL C YC + E T KP+ EI R+ +
Sbjct: 65 MLIDKFGRLHTYLRISLTERCNLRCQYCMPSEGV--ELTPKPQLLSQSEIVRLAGLFVSA 122
Query: 56 GIKKVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVNI 113
G+ K++LTGGEPT+RKDI EI ++ + +L++TTNG TL LKE GLD +NI
Sbjct: 123 GVNKIRLTGGEPTVRKDIEEICLQLSSLKGLKNLAITTNGITLAKKLPRLKECGLDSLNI 182
Query: 114 SLDTLDRKKYKMITGFDVLDQVIKGIEKATKLFY-PVKLNMVVMRGINDDEIWDLIRFAG 172
SLDTL K++ +T D+V+K I+ A +L Y PVK+N V+MRG+NDDEI D +
Sbjct: 183 SLDTLVPAKFEFLTRRKGHDRVMKSIDTAIELGYNPVKVNCVIMRGLNDDEICDFVELTR 242
Query: 173 KVNAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMH--RRRKYFLP 230
++ IE + + + P + ++ K I+ + H K F
Sbjct: 243 DKPINVRFIEF---MPFDGNVWNVKKLVPYAEVMDKVVKRFPSIKRMQDHPTETAKNF-T 298
Query: 231 VDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAEL 290
+DG V + SM FC C RLRL ADG K CL + + + PLR+GA D L
Sbjct: 299 IDGHCGSVSFITSM-TEHFCAGCNRLRLLADGNFKVCLFGPSE-VSLRDPLRSGADDEAL 356
Query: 291 VDIFKRAVLMRR 302
+I AV ++
Sbjct: 357 REIIGAAVKRKK 368
>pir||A81434 molybdenum cofactor biosynthesis protein A Cj0161c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967655|emb|CAB72645.1| (AL139074) molybdenum
cofactor biosynthesis protein A [Campylobacter jejuni]
Length = 320
Score = 171 bits (428), Expect = 1e-41
Identities = 117/309 (37%), Positives = 173/309 (55%), Gaps = 17/309 (5%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLD---GERTMKPEEIERIVRIASRLGI 57
MLID+FGR + LRIS+T+ CN C YC + D E + EE+ V+ A GI
Sbjct: 1 MLIDQFGRKINYLRISVTQRCNFRCLYCMPKIPFDYQPKENLLSFEELFLFVKAAIDEGI 60
Query: 58 KKVKLTGGEPTIRKDIVEIIRRIRPYV--VDLSLTTNGTTLYTLAEELKEAGLDRVNISL 115
+K+++TGGEP +RKD+ I+ I Y +DL++TTNG L A++LK AGL R+NISL
Sbjct: 61 EKIRITGGEPLLRKDLSIFIKMISDYKSDIDLAITTNGFLLKDFAKDLKNAGLKRLNISL 120
Query: 116 DTLDRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVN 175
DTLD KK K + DVLD V+ GI++A L VKLN V ++ +NDDE+ L+ FA
Sbjct: 121 DTLDHKKAKTLAQKDVLDSVLSGIDEALNLDLKVKLNTVALKNLNDDELISLLEFAKSKK 180
Query: 176 AILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKV 235
A ++ IE MEN+ + LK +E +I + + ++ ++ + K
Sbjct: 181 AQIRFIEF-----MENTHAYGK-LQGLK--RDEIIQILSQKYQIQLIKKDEKAPVSIYKA 232
Query: 236 VEVEV-VRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIF 294
+ E + H+ FC +C R+RL+A+G L CL D+ + I +R G A V+I
Sbjct: 233 DDYEFGIIDPHSHEFCDSCNRIRLSAEGLLIPCLY-FDEALSIKEAVRKGDIKA-AVEIL 290
Query: 295 KRAVLMRRP 303
+ VL +P
Sbjct: 291 QE-VLRNKP 298
>pir||T22465 hypothetical protein F49H6.5 - Caenorhabditis elegans
>gi|3947550|emb|CAB04440.1| (Z81545) contains similarity
to Pfam domain: PF01444 (moaA / nifB / pqqE family),
Score=276.1, E-value=1.4e-79, N=1 [Caenorhabditis
elegans]
Length = 389
Score = 167 bits (419), Expect = 1e-40
Identities = 107/303 (35%), Positives = 169/303 (55%), Gaps = 14/303 (4%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQLD---GERTMKPEEIERIVRIASRLGIKKV 60
D F R T LRISLT++CN C YC + ++ + E+ R+V++ + G+ KV
Sbjct: 67 DMFMREHTYLRISLTEKCNFRCLYCMPAEGIPLKPKDKMLSNSEVLRLVKLFAAHGVDKV 126
Query: 61 KLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTL 118
+LTGGEPTIR D+V+I+ I P + ++ +TTNG L +LK+AGL ++NIS+D+L
Sbjct: 127 RLTGGEPTIRNDLVQIVEGISSTPGIKEVGITTNGLVLPRFLPKLKDAGLTKINISIDSL 186
Query: 119 DRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAIL 178
DR+K+ +T D D+V K IE A F VKLN+VV++ N++EI D + N +
Sbjct: 187 DREKFAKMTRRDGFDKVWKAIELARGYFPKVKLNVVVLKHQNENEIVDFVNLTKGRNLDI 246
Query: 179 QLIEIEVP---REMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKV 235
+ IE +P E +N F + L + +++ + + + + Y +DG
Sbjct: 247 RFIEF-MPFGGNEFKNDSFM-SYREMLNLIVDKYGDAVIRLSDLPNDTTKAY--KIDGFQ 302
Query: 236 VEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFK 295
+ + SM + FC C RLR+TADG LK CL + + + +R G SDA+L ++ +
Sbjct: 303 GQFGFITSMSDH-FCNTCNRLRITADGNLKVCLHGNSE-VSLRDRIRCGDSDAKLSEVIQ 360
Query: 296 RAV 298
AV
Sbjct: 361 TAV 363
>gb|AAG18718.1| (AE004976) molybdenum cofactor biosynthesis protein; MoaA
[Halobacterium sp. NRC-1]
Length = 367
Score = 167 bits (419), Expect = 1e-40
Identities = 123/333 (36%), Positives = 163/333 (48%), Gaps = 40/333 (12%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIE----RIVR---IAS 53
ML D FGR V+ +R+SLT CN +C YCH EG D + P E E R+VR +A
Sbjct: 11 MLEDDFGRDVSGVRVSLTDRCNFDCVYCHNEGLGDTRGPIDPRENELSTDRVVRFLSVAH 70
Query: 54 RLGIKKVKLTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNI 113
G+ VKLTGGEP +R D+ IIRR P + +S+TTNGT L A +L +AGL+RVNI
Sbjct: 71 EFGVDAVKLTGGEPMLRSDLEAIIRRT-PDDMAVSMTTNGTFLPGRAADLVDAGLERVNI 129
Query: 114 SLDTLDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAG 172
S D +D + +T D V++G+E A PVKLNMVV + A
Sbjct: 130 SQDAMDNDAFAELTQSGAYDAVLEGVEAALDAGLAPVKLNMVVFEPTAGYVPEMVDHVAA 189
Query: 173 KVNAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFL--- 229
+ LQLIE M ++ + + + A I R MH RR+Y++
Sbjct: 190 RDGLRLQLIEY-----MPELAGHPEWAIDIDRVHDWLADRADRIETREMHDRRRYWVSSR 244
Query: 230 --------------PVDGKVVE---VEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRD 272
P G + VE+V + N FC NC R+RLT DGYLK CL R D
Sbjct: 245 DAGSTADDAAQSVTPDGGAHPDQGMVEIVDPVGNPQFCANCHRVRLTHDGYLKGCLNRND 304
Query: 273 DLIDILGPLRNGASDAELVDIFKRAVLMRRPYW 305
DL I G + + F+ V R PY+
Sbjct: 305 DLRGI------GETTQSMRAAFRETVANRVPYY 331
>sp|Q20624|YL71_CAEEL HYPOTHETICAL 64.9 KD PROTEIN F49E2.1 IN CHROMOSOME X
>gi|7503858|pir||T22460 hypothetical protein F49E2.1 -
Caenorhabditis elegans >gi|3877388|emb|CAA86430.1|
(Z46267) contains similarity to Pfam domain: PF01444
(moaA / nifB / pqqE family), Score=280.9,
E-value=5.2e-81, N=1; PF01967 (MoaC family),
Score=299.5, E-value=1.3e-86, N=1~cDNA EST yk433a8.5
comes from this gene~cDNA EST yk433a8.3 comes from this
gene
Length = 577
Score = 166 bits (416), Expect = 3e-40
Identities = 107/303 (35%), Positives = 170/303 (55%), Gaps = 14/303 (4%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCH-REGQ--LDGERTMKPEEIERIVRIASRLGIKKV 60
D F R T LRISLT++CN C YC EG ++ + E+ R+V++ + G+ KV
Sbjct: 67 DMFMREHTYLRISLTEKCNFRCLYCMPAEGVPLKPKDKMLSNSEVLRLVKLFAAHGVDKV 126
Query: 61 KLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTL 118
+LTGGEPTIRKDIV I+ I P + ++ +TTNG L +L++AGL ++NIS+D+L
Sbjct: 127 RLTGGEPTIRKDIVHIVEGISSTPGIKEVGITTNGLVLQRFLPQLRDAGLTKINISIDSL 186
Query: 119 DRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAIL 178
DR+K+ +T D D+V K IE A + VKLN+VV++ N++E+ D + N +
Sbjct: 187 DREKFAKMTRRDGFDKVWKAIELARGYYPKVKLNVVVLKHQNENEVVDFVNLTKDRNLDV 246
Query: 179 QLIEIEVP---REMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKV 235
+ IE +P E +N F + L + +++ + + + + Y +DG
Sbjct: 247 RFIEF-MPFGGNEFKNDNFI-GYREMLNLIVDKYGDGVIRLSDSPNDTTKAY--KIDGFQ 302
Query: 236 VEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDIFK 295
+ + SM + FC C RLR+TADG LK CL + + + +R G SD +L ++ +
Sbjct: 303 GQFGFITSMSDH-FCNTCNRLRITADGNLKVCLHGNSE-VSLRDRIRCGDSDEQLSEVIQ 360
Query: 296 RAV 298
+AV
Sbjct: 361 KAV 363
>emb|CAB59437.1| (AL132644) molybdenum cofactor biosynthesis protein A [Streptomyces
coelicolor A3(2)]
Length = 341
Score = 165 bits (413), Expect = 7e-40
Identities = 119/311 (38%), Positives = 171/311 (54%), Gaps = 21/311 (6%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDG---ERTMKPEEIERIVRIA-SRLG 56
+LID +GR T+LR+SLT CNL C YC E L + +EI R++ IA + LG
Sbjct: 13 VLIDTYGRVATDLRVSLTDRCNLRCTYCMPEEGLQWLAKPDLLTDDEIVRLIDIAVTSLG 72
Query: 57 IKKVKLTGGEPTIRKDIVEIIRRI-----RPYVVDLSLTTNGTTLYTLAEELKEAGLDRV 111
I++V+ TGGEP +R +V I+ R+ RP +SLTTNG L A LK AGLDRV
Sbjct: 73 IEEVRFTGGEPLLRPGLVGIVERVAALEPRP---QMSLTTNGIGLRRTATALKAAGLDRV 129
Query: 112 NISLDTLDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRF 170
N+SLDTL +K +T D V++G+ A + PVK+N V+M G+NDDE DL+ +
Sbjct: 130 NVSLDTLRPDVFKTLTRRDRHKDVLEGLAAAREAGLTPVKVNSVLMPGLNDDEAPDLLAW 189
Query: 171 AGKVNAILQLIEIEVPREMENSQFFKDFFYP---LKPLEEEFEKIAVEIRERRMHRRRKY 227
A + + L+ IE ++P + ++ + L L FE A ER ++
Sbjct: 190 AVEHDYELRFIE-QMPLDAQHGWKREGMVTAGDILTSLRTRFELTAEGSEERGSAPAERW 248
Query: 228 FLPVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASD 287
VDG V V+ S+ FC C R RLTADG ++TCL ++ D+ LR+ A D
Sbjct: 249 L--VDGGPHRVGVIASV-TRPFCSACDRTRLTADGQVRTCLFATEE-TDLRAALRSDAPD 304
Query: 288 AELVDIFKRAV 298
E+ I++ A+
Sbjct: 305 EEIARIWRLAM 315
>gb|AAF50108.1| (AE003546) Mocs1 gene product [Drosophila melanogaster]
Length = 552
Score = 163 bits (408), Expect = 3e-39
Identities = 114/311 (36%), Positives = 167/311 (53%), Gaps = 18/311 (5%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCH-REGQ--LDGERTMKPEEIERIVRIASRLGIK 58
L D FGR T LRISLT+ CNL C YC EG + + EEI R+ RI G++
Sbjct: 61 LTDSFGRHHTYLRISLTERCNLRCDYCMPAEGVPLQPKNKLLTTEEILRLARIFVEQGVR 120
Query: 59 KVKLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLD 116
K++LTGGEPT+R+DIVEI+ +++ P + + +TTNG L L L+ AGLD +NISLD
Sbjct: 121 KIRLTGGEPTVRRDIVEIVAQMKALPELEQIGITTNGLVLTRLLLPLQRAGLDNLNISLD 180
Query: 117 TLDRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNA 176
TL R +++ IT ++VI GI+ A +L Y K+N V+MR N+DEI D + F
Sbjct: 181 TLKRDRFEKITRRKGWERVIAGIDLAVQLGYRPKVNCVLMRDFNEDEICDFVEFTRNRPV 240
Query: 177 ILQLIEIEV----PREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVD 232
++ IE E +KD ++ +F+ + + + Y +P
Sbjct: 241 DVRFIEYMPFSGNKWHTERLISYKDTLQIIRQRWPDFKALPNGPND----TSKAYAVP-- 294
Query: 233 GKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRN-GASDAELV 291
G +V + SM FC C RLRLTADG +K CL + + +R+ S+ +LV
Sbjct: 295 GFKGQVGFITSM-TEHFCGTCNRLRLTADGNIKVCLFGNKE-FSLRDAMRDESVSEEQLV 352
Query: 292 DIFKRAVLMRR 302
D+ AV ++
Sbjct: 353 DLIGAAVQRKK 363
>sp|O67929|MOAA_AQUAE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A >gi|7429624|pir||E70487
molybdenum cofactor biosynthesis protein A - Aquifex
aeolicus >gi|2984358|gb|AAC07877.1| (AE000776)
molybdenum cofactor biosynthesis protein A [Aquifex
aeolicus]
Length = 320
Score = 163 bits (408), Expect = 3e-39
Identities = 106/279 (37%), Positives = 157/279 (55%), Gaps = 19/279 (6%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQ----LDGERTMKPEEIERIVRIASRLG 56
ML+D+ RP+ LRISLT CNL C +C G+ L + + PEEIE V+I ++LG
Sbjct: 1 MLLDKLSRPLKVLRISLTDRCNLRCNFCMPPGKEYNFLPKRQLLTPEEIEEYVKIFAKLG 60
Query: 57 IKKVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVNIS 114
++KV+LTGGEP +R+D+ EII+RI + D++LTTNG L + LKEAGL R+ +S
Sbjct: 61 VEKVRLTGGEPLLREDLEEIIQRISKVEGIKDIALTTNGVFLKERLKALKEAGLKRITVS 120
Query: 115 LDTLDRKKYKMITGFDV-LDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGK 173
+ +L+ +K + + V L +V + I +A +L + VK+N V+++G NDDEI DL RF
Sbjct: 121 VHSLNPEKNQKLVNRSVNLGEVFEVIIRAKELGFKVKVNSVIIKGFNDDEILDLARFFKN 180
Query: 174 VNAILQLIEIEVPREMENSQFFK----DFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFL 229
+ L+ IE + + F K D L E F + + M F+
Sbjct: 181 LGVTLRFIEYMDVGTVNDWDFSKVVSADEILNLMKKEFTFYPLPKRPEDTSMD-----FI 235
Query: 230 PVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCL 268
DG + ++ S+ FC C R+RL+ADG L TCL
Sbjct: 236 YEDGN--KFGIIASV-TKPFCRGCNRIRLSADGKLYTCL 271
>gb|AAF67855.1|AF214021_1 (AF214021) molybdenum cofactor synthesis-step 1 protein A splice
type I [Drosophila melanogaster]
Length = 385
Score = 162 bits (406), Expect = 5e-39
Identities = 114/311 (36%), Positives = 167/311 (53%), Gaps = 18/311 (5%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCH-REGQ--LDGERTMKPEEIERIVRIASRLGIK 58
L D FGR T LRISLT+ CNL C YC EG + + EEI R+ RI G++
Sbjct: 61 LTDSFGRHHTYLRISLTERCNLRCDYCMPAEGVPLQPKNKLLTTEEILRLARIFVDQGVR 120
Query: 59 KVKLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLD 116
K++LTGGEPT+R+DIVEI+ +++ P + + +TTNG L L L+ AGLD +NISLD
Sbjct: 121 KIRLTGGEPTVRRDIVEIVAQMKALPELEQIGITTNGLVLTRLLLPLQRAGLDNLNISLD 180
Query: 117 TLDRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNA 176
TL R +++ IT ++VI GI+ A +L Y K+N V+MR N+DEI D + F
Sbjct: 181 TLKRDRFEKITRRKGWERVIAGIDLAVQLGYRPKVNCVLMRDFNEDEICDFVEFTRNRPV 240
Query: 177 ILQLIEIEV----PREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVD 232
++ IE E +KD ++ +F+ + + + Y +P
Sbjct: 241 DVRFIEYMPFSGNKWHTERLISYKDTLQIIRQRWPDFKALPNGPND----TSKAYAVP-- 294
Query: 233 GKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRN-GASDAELV 291
G +V + SM FC C RLRLTADG +K CL + + +R+ S+ +LV
Sbjct: 295 GFKGQVGFITSM-TEHFCGTCNRLRLTADGNIKVCLFGNKE-FSLRDAMRDESVSEEQLV 352
Query: 292 DIFKRAVLMRR 302
D+ AV ++
Sbjct: 353 DLIGAAVQRKK 363
>emb|CAA11897.1| (AJ224328) MOCS1A protein [Homo sapiens]
Length = 385
Score = 162 bits (406), Expect = 5e-39
Identities = 111/305 (36%), Positives = 170/305 (55%), Gaps = 14/305 (4%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLD---GERTMKPEEIERIVRIASRLGIK 58
L D FGR + LRISLT++CNL C YC E + + EEI + R+ + GI
Sbjct: 61 LTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGID 120
Query: 59 KVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVNISLD 116
K++LTGGEP IR D+V+I+ +++ + + +TTNG L L +L++AGL +NISLD
Sbjct: 121 KIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLD 180
Query: 117 TLDRKKYKMITGFDVLDQVIKGIEKATKLFY-PVKLNMVVMRGINDDEIWDLIRFAGKVN 175
TL K++ I +V++GI KA +L Y PVK+N VVMRG+N+DE+ D +
Sbjct: 181 TLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLP 240
Query: 176 AILQLIEIEVPREMENSQFFKDFFYP--LKPLEEEFEKIAVEIRERRMHRRRKYFLPVDG 233
++ IE +P + F K Y L + +++ ++ ++ E + + +P G
Sbjct: 241 LDVRFIEY-MPFDGNKWNFKKMVSYKEMLDTVRQQWPELE-KVPEEESSTAKAFKIP--G 296
Query: 234 KVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDI 293
++ + SM + FC C RLR+TADG LK CL + + + LR GAS+ EL+ I
Sbjct: 297 FQGQISFITSM-SEHFCGTCNRLRITADGNLKVCLFGNSE-VSLRDHLRAGASEQELLRI 354
Query: 294 FKRAV 298
AV
Sbjct: 355 IGAAV 359
>pir||S57490 molybdopterin cofactor synthesis protein - Arthrobacter
nicotinovorans (fragment) >gi|2147736|pir||I39637
molybdopterin cofactor synthesis protein - Arthrobacter
nicotinovorans (fragment) >gi|871980|emb|CAA55583.1|
(X78980) molybdopterin cofactor synthesis protein
[Arthrobacter nicotinovorans]
Length = 374
Score = 161 bits (403), Expect = 1e-38
Identities = 120/321 (37%), Positives = 175/321 (54%), Gaps = 27/321 (8%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCH-REGQ--LDGERTMKPEEIERIVRIA-SRLGI 57
L+DR+GR T++R+SLT +CNL C YC EG L + M EI RIV I RLG+
Sbjct: 32 LVDRYGRRATDMRLSLTDKCNLRCTYCMPAEGLEWLSKQAVMSASEIVRIVGIGVGRLGV 91
Query: 58 KKVKLTGGEPTIRKDIVEIIRRIRPYVVDL--SLTTNGTTLYTLAEELKEAGLDRVNISL 115
++++LTGGEP +R D+V+II +R +L S+TTNG L LK AGL R+N+SL
Sbjct: 92 RELRLTGGEPLVRHDLVDIIAELRRNHPELPISMTTNGVGLAKKVAPLKAAGLTRINVSL 151
Query: 116 DTLDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKV 174
D+L + + +T LDQV+ G++ A PVKLN V+MRGIND E L+ +A +
Sbjct: 152 DSLHEETFTKLTRRPFLDQVLAGVDAAWAAGLGPVKLNAVLMRGINDAEAPSLLAWAVER 211
Query: 175 NAILQLIEIEVP---------REMENSQFFKDFF---YPLKPLEEEFEKIAVEIRE--RR 220
L+ IE ++P R M + +D + L P + E E RR
Sbjct: 212 GYELRFIE-QMPLDADHGWTRRNMITAAEIRDLLSTDFVLTPDPRARDGAPAERFEVRRR 270
Query: 221 MHRRRKYFLPVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGP 280
+ PV G V + V FC +C R R+TA+G + +CL R++ D+L
Sbjct: 271 VAGSGAGLGPVLGTVGIIASV----TEPFCSDCRRTRITAEGRIMSCLFSREE-FDLLVL 325
Query: 281 LRNGASDAELVDIFKRAVLMR 301
LR+GASD +L ++ A+ ++
Sbjct: 326 LRSGASDDDLARRWQDAMWLK 346
>sp|Q44118|MOAA_ARTNI PROBABLE MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A
>gi|11278718|pir||T44850 molybdopterin co-factor
synthesis protein moaA [imported] - Arthrobacter
nicotinovorans plasmid pAO1 >gi|2288875|emb|CAA71779.1|
(Y10817) molybdopterin co-factor synthesis protein
[Arthrobacter nicotinovorans]
Length = 355
Score = 161 bits (403), Expect = 1e-38
Identities = 120/321 (37%), Positives = 175/321 (54%), Gaps = 27/321 (8%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCH-REGQ--LDGERTMKPEEIERIVRIA-SRLGI 57
L+DR+GR T++R+SLT +CNL C YC EG L + M EI RIV I RLG+
Sbjct: 13 LVDRYGRRATDMRLSLTDKCNLRCTYCMPAEGLEWLSKQAVMSASEIVRIVGIGVGRLGV 72
Query: 58 KKVKLTGGEPTIRKDIVEIIRRIRPYVVDL--SLTTNGTTLYTLAEELKEAGLDRVNISL 115
++++LTGGEP +R D+V+II +R +L S+TTNG L LK AGL R+N+SL
Sbjct: 73 RELRLTGGEPLVRHDLVDIIAELRRNHPELPISMTTNGVGLAKKVAPLKAAGLTRINVSL 132
Query: 116 DTLDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKV 174
D+L + + +T LDQV+ G++ A PVKLN V+MRGIND E L+ +A +
Sbjct: 133 DSLHEETFTKLTRRPFLDQVLAGVDAAWAAGLGPVKLNAVLMRGINDAEAPSLLAWAVER 192
Query: 175 NAILQLIEIEVP---------REMENSQFFKDFF---YPLKPLEEEFEKIAVEIRE--RR 220
L+ IE ++P R M + +D + L P + E E RR
Sbjct: 193 GYELRFIE-QMPLDADHGWTRRNMITAAEIRDLLSTDFVLTPDPRARDGAPAERFEVRRR 251
Query: 221 MHRRRKYFLPVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGP 280
+ PV G V + V FC +C R R+TA+G + +CL R++ D+L
Sbjct: 252 VAGSGAGLGPVLGTVGIIASV----TEPFCSDCRRTRITAEGRIMSCLFSREE-FDLLVL 306
Query: 281 LRNGASDAELVDIFKRAVLMR 301
LR+GASD +L ++ A+ ++
Sbjct: 307 LRSGASDDDLARRWQDAMWLK 327
>gb|AAB87523.1| (AF034374) molybdenum cofactor biosynthesis protein A [Homo
sapiens]
Length = 385
Score = 161 bits (402), Expect = 1e-38
Identities = 111/305 (36%), Positives = 169/305 (55%), Gaps = 14/305 (4%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLD---GERTMKPEEIERIVRIASRLGIK 58
L D FGR + LRISLT++CNL C YC E + + EEI + R+ + GI
Sbjct: 61 LTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGID 120
Query: 59 KVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVNISLD 116
K++LTGGEP IR D+V+I+ +++ + + +TTNG L L +L++AGL +NISLD
Sbjct: 121 KIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLD 180
Query: 117 TLDRKKYKMITGFDVLDQVIKGIEKATKLFY-PVKLNMVVMRGINDDEIWDLIRFAGKVN 175
TL K++ I +V++GI KA +L Y PVK+N VVMRG+N+DE+ D
Sbjct: 181 TLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGHP 240
Query: 176 AILQLIEIEVPREMENSQFFKDFFYP--LKPLEEEFEKIAVEIRERRMHRRRKYFLPVDG 233
++ IE +P + F K Y L + +++ ++ ++ E + + +P G
Sbjct: 241 LDVRFIEY-MPFDGNKWNFKKMVSYKEMLDTVRQQWPELE-KVPEEESSTAKAFKIP--G 296
Query: 234 KVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELVDI 293
++ + SM + FC C RLR+TADG LK CL + + + LR GAS+ EL+ I
Sbjct: 297 FQGQISFITSM-SEHFCGTCNRLRITADGNLKVCLFGNSE-VSLRDHLRAGASEQELLRI 354
Query: 294 FKRAV 298
AV
Sbjct: 355 IGAAV 359
>sp|P39757|MOAA_BACSU MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A (NARA PROTEIN)
>gi|7429623|pir||D69664 molybdenum cofactor biosynthesis
protein narA - Bacillus subtilis
>gi|516272|emb|CAA84540.1| (Z35277) unknown [Bacillus
subtilis] >gi|1648856|emb|CAB03683.1| (Z81356) MoaA-like
protein [Bacillus subtilis] >gi|2636195|emb|CAB15687.1|
(Z99122) alternate gene name: narAB [Bacillus subtilis]
Length = 341
Score = 160 bits (401), Expect = 2e-38
Identities = 109/305 (35%), Positives = 174/305 (56%), Gaps = 18/305 (5%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDG--------ERTMKPEEIERIVRI-A 52
++D+ RP+ +LRIS+T CN C YC +L G E + EE+ER+ +
Sbjct: 8 MLDKRNRPLRDLRISVTDRCNFRCTYC-MPAELFGPDYPFLKKEELLSFEELERLATLFV 66
Query: 53 SRLGIKKVKLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDR 110
+R G++K++LTGGEP +RKD+ E+I+++ P + D+++TTNG+ L A+ LKEAGL R
Sbjct: 67 TRFGVEKIRLTGGEPLMRKDMPELIKKLARIPGIRDIAMTTNGSLLPVYAKRLKEAGLKR 126
Query: 111 VNISLDTLDRKKYKMITGFDV-LDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIR 169
V ISLD+L+ +++K I G V + +V++GIE A + VK+NMVV +G+N+ +I + R
Sbjct: 127 VTISLDSLEDERFKKINGRGVSVSKVLEGIEAAKQAGLGVKINMVVQKGVNEKDILPMAR 186
Query: 170 FAGKVNAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVE-IRERRMHRRRKYF 228
+ + IL+ IE + N KD + ++ + + VE I + F
Sbjct: 187 YFKEKGHILRFIEF-MDVGNTNQWEKKDVMTKAEIIDLINKHMPVEPIAPNYIGEVASRF 245
Query: 229 LPVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDA 288
+DG E+ V+ S+ + FC +C R RL+A G L TCL D+ P+R SD
Sbjct: 246 RYLDGS-GEIGVISSV-SDAFCGSCNRARLSARGELFTCLFASSG-FDLRAPVRQELSDD 302
Query: 289 ELVDI 293
EL ++
Sbjct: 303 ELSEM 307
>sp|Q9ZIM6|MOAA_STACA MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A
>gi|3955209|gb|AAC83144.1| (AF109295) MoaA
[Staphylococcus carnosus]
Length = 340
Score = 157 bits (394), Expect = 1e-37
Identities = 97/301 (32%), Positives = 164/301 (54%), Gaps = 16/301 (5%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPE-------EIERIVRIASR 54
+ D+ GRP+ +LR+S+T CN C YC + + P+ E+ERI R+ +
Sbjct: 5 ITDKLGRPIRDLRLSVTDRCNFRCDYCMPKEIFGDDFVFLPKDELLSFSEMERIARVYTH 64
Query: 55 LGIKKVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVN 112
LG+KK+++TGGEP +R+D+ ++I + V D+ LTTNG L ++L +AGL R+N
Sbjct: 65 LGVKKIRITGGEPLMRRDLYKLIAALNEIEGVEDIGLTTNGLLLKKHGQKLYDAGLRRIN 124
Query: 113 ISLDTLDRKKYKMITGFDV-LDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFA 171
+SLD +D + ++ I ++ D +++ I+ A + + VK+N+VV +G+NDD+I ++++
Sbjct: 125 VSLDAIDNELFQSINNRNIKADTILEQIDYAVSIGFKVKINVVVQKGVNDDQIIPMVQYF 184
Query: 172 GKVNAILQLIEIEVPREMENSQFFKDFFYP--LKPLEEEFEKIAVEIRERRMHRRRKYFL 229
N ++ IE F K L ++EEF+ AVE + KY+
Sbjct: 185 KDKNIQVRFIEFMDVGNDNGWDFSKVVSKDEMLSMIQEEFDIEAVE--PKYYGEVAKYYR 242
Query: 230 PVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAE 289
D + ++ S+ + FC CTR RL++DG CL D ++ +R+G SD E
Sbjct: 243 HKDNG-AQFGLITSVSQS-FCSTCTRARLSSDGKFYGCLFSTVDGFNVKEFMRSGVSDDE 300
Query: 290 L 290
L
Sbjct: 301 L 301
>sp|Q9ZL75|MOAA_HELPJ MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A >gi|7445220|pir||A71900
molybdopterin cofactor biosynthetic protein -
Helicobacter pylori (strain J99)
>gi|4155260|gb|AAD06280.1| (AE001501) MOLYBDOPTERIN
COFACTOR BIOSYNTHETIC PROTEIN [Helicobacter pylori J99]
Length = 321
Score = 157 bits (393), Expect = 2e-37
Identities = 99/282 (35%), Positives = 159/282 (56%), Gaps = 21/282 (7%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQLD---GERTMKPEEIERIVRIASRLGI 57
ML+D F R + +R+S+TK+CN C YC LD E + + + ++IA G+
Sbjct: 1 MLVDSFNRVIDYIRVSVTKQCNFRCQYCMPTTPLDFFDDEELLPLDNVLEFLKIAIDEGV 60
Query: 58 KKVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVNISL 115
KK+++TGGEP +RK + E I ++ Y V L L+TNG +L +A+ LK+AGL RVN+SL
Sbjct: 61 KKIRITGGEPLLRKGLDEFIAKLHAYNKEVALVLSTNGFSLKKMAKGLKDAGLSRVNVSL 120
Query: 116 DTLDRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVN 175
D+L + I+ D L ++GIE++ K+ +KLN VVM+G+NDDEI +L+ +A +
Sbjct: 121 DSLKSDRVLKISQKDALKNTLEGIEESLKVGLKLKLNTVVMKGVNDDEILELLEYAKNRS 180
Query: 176 AILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKV 235
++ IE MEN+ K LK +E + IA + + M + ++ K+
Sbjct: 181 IQIRYIEF-----MENTH-AKSLVKGLKE-KEILDLIAQKYKIMGMEKPKQ----GSSKI 229
Query: 236 VEVE-----VVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRD 272
+E + + H+ FC +C R+RL +DG + CL +D
Sbjct: 230 YTLENGYQFGIIAPHSDDFCQSCNRIRLASDGKICPCLYYQD 271
>sp|P56414|MOAA_HELPY MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A >gi|7429628|pir||H64615
molybdenum cofactor biosynthesis protein A -
Helicobacter pylori (strain 26695)
>gi|2313896|gb|AAD07817.1| (AE000589) molybdenum
cofactor biosynthesis protein A (moaA) [Helicobacter
pylori 26695]
Length = 321
Score = 151 bits (378), Expect = 9e-36
Identities = 95/280 (33%), Positives = 154/280 (54%), Gaps = 17/280 (6%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQL---DGERTMKPEEIERIVRIASRLGI 57
ML+D F R + +R+S+TK+CN C YC L D E + + + ++IA G+
Sbjct: 1 MLVDSFNRVIDYIRVSVTKQCNFRCQYCMPATPLNFFDNEELLPLDNVLEFLKIAIDEGV 60
Query: 58 KKVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVNISL 115
KK+++TGGEP +RK + E I ++ Y V+L L+TNG L +A++LK AGL +VN+SL
Sbjct: 61 KKIRITGGEPLLRKGLDEFIAKLHAYNKEVELVLSTNGFLLKKMAKDLKNAGLAQVNVSL 120
Query: 116 DTLDRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVN 175
D+L + I+ D L ++GIE++ K+ +KLN VV++ +NDDEI +L+ +A +
Sbjct: 121 DSLKSDRVLKISQKDALKNTLEGIEESLKVGLKLKLNTVVIKSVNDDEILELLEYAKNRH 180
Query: 176 AILQLIEIEVPREMENSQFFKDFFYPLKP---LEEEFEKIAVEIRERRMHRRRKYFLPVD 232
++ IE MEN+ K LK L+ +K + E+ K + +
Sbjct: 181 IQIRYIEF-----MENTH-AKSLVKGLKEREILDLIAQKYQIIEAEKPKQGSSKIYTLEN 234
Query: 233 GKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRD 272
G + + H+ FC +C R+RL +DG + CL +D
Sbjct: 235 GYQFG---IIAPHSDDFCQSCNRIRLASDGKICPCLYYQD 271
>sp|O53881|MOA2_MYCTU MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A 2
>gi|7429625|pir||E70816 probable moaA2 protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2916928|emb|CAA17675.1| (AL022004) moaA2
[Mycobacterium tuberculosis]
Length = 360
Score = 150 bits (374), Expect = 3e-35
Identities = 110/323 (34%), Positives = 168/323 (51%), Gaps = 35/323 (10%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQL---DGERTMKPEEIERIVRIA-SRLGI 57
L+D FGR +LR+SLT CNL C YC E L GE+ ++P+E+ R++ IA +RLG+
Sbjct: 30 LVDTFGRVANDLRVSLTDRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLGV 89
Query: 58 KKVKLTGGEPTIRKDIVEIIR---RIRPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNIS 114
V+ TGGEP + + E++ R+RP ++SLTTNG L A L EAGLDRVN+S
Sbjct: 90 TSVRFTGGEPLLAHHLDEVVAATARLRPRP-EISLTTNGVGLARRAGALAEAGLDRVNVS 148
Query: 115 LDTLDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGK 173
LD++DR + IT D L V+ G+ A PVK+N V+ +++ DL+RF +
Sbjct: 149 LDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTPVKVNAVLDPTTGREDVVDLLRFCLE 208
Query: 174 VNAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDG 233
L++IE ++P + +S + + + + +R R R P
Sbjct: 209 RGYQLRVIE-QMPLDAGHSW--------RRNIALSADDVLAALRPH--FRLRPDPAPRGS 257
Query: 234 KVVEVEVVRSMHNT-------------VFCMNCTRLRLTADGYLKTCLLRRDDLIDILGP 280
E+ +V + NT FC C R RLTADG +++CL ++ D+
Sbjct: 258 APAELWLVDAGPNTPRGRFGVIASVSHAFCSTCDRTRLTADGQIRSCLFSTEE-TDLRRL 316
Query: 281 LRNGASDAELVDIFKRAVLMRRP 303
LR GA D + ++ RA + +P
Sbjct: 317 LRGGADD-DAIEAAWRAAMWSKP 338
>pir||E83457 molybdopterin biosynthetic protein A2 PA1505 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9947461|gb|AAG04894.1|AE004579_6 (AE004579)
molybdopterin biosynthetic protein A2 [Pseudomonas
aeruginosa]
Length = 331
Score = 148 bits (371), Expect = 6e-35
Identities = 104/317 (32%), Positives = 164/317 (50%), Gaps = 28/317 (8%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQ--LDGERTMKPEEIERIVRIASRLGIKK 59
L+D FGR +T LR+S+T C+ C YC E L ++ + EE+ + LG+++
Sbjct: 6 LVDPFGRRITYLRLSVTDRCDFRCTYCMSEDMQFLPRDQVLSLEELYAVADAFIGLGVRR 65
Query: 60 VKLTGGEPTIRKDIVEIIRRI--RPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDT 117
+++TGGEP +RK I ++ R+ R + DL++TTNG+ L A ELK AG+ R+N+SLD+
Sbjct: 66 IRITGGEPLVRKGITGLLARLGQRAELEDLAITTNGSQLRERAAELKAAGVRRLNVSLDS 125
Query: 118 LDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNA 176
L R+++ T D L+QV+ GI+ A + F +KLN VV +G NDDEI DL+ +A
Sbjct: 126 LQRERFAAFTRSDRLEQVLDGIQAAREAGFERIKLNCVVQKGRNDDEILDLVEYALANQL 185
Query: 177 ILQLIEIEVP--------REME--NSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRK 226
+ IE E+P RE+ S + PL + R
Sbjct: 186 DISFIE-EMPLGSITSHRRELTLCTSDEVRAIIERRWPLTPSLARSGGPSR--------- 235
Query: 227 YFLPVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGAS 286
+ + + + + S H+ FC +C R+R+TA+G L C L + +D+ LR+
Sbjct: 236 -YYQIGDEPSRIGFI-SPHSNNFCGDCNRVRVTAEGKLVLC-LGHEGALDLRELLRSHPG 292
Query: 287 DAELVDIFKRAVLMRRP 303
D E + A L +P
Sbjct: 293 DRERLSAALVAALNLKP 309
>sp|O05786|MOA1_MYCTU MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A 1
>gi|7429627|pir||D70920 probable moaA protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2076684|emb|CAB08366.1| (Z95150) moaA [Mycobacterium
tuberculosis]
Length = 359
Score = 145 bits (362), Expect = 7e-34
Identities = 108/301 (35%), Positives = 158/301 (51%), Gaps = 18/301 (5%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQ---LDGERTMKPEEIERIVRIASRLGIKKV 60
DR R + +LR+S+ +CNL C YC E L + + +EI IV + +G+ KV
Sbjct: 20 DRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKV 79
Query: 61 KLTGGEPTIRKDIVEIIRRIRPYVV------DLSLTTNGTTLYTLAEELKEAGLDRVNIS 114
++TGGEP IR D+ EI+R + V DL++TTNG L + LK AG+ R+ +S
Sbjct: 80 RITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVS 139
Query: 115 LDTLDRKKYKMITGFDVLDQVIKGIEK-ATKLFYPVKLNMVVMRGINDDEIWDLIRFAGK 173
LDTL +++K I+ + D+VI GI+ A F K++ VMRG N DE+ DLI FA
Sbjct: 140 LDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFART 199
Query: 174 VNAILQLIEIEVPREMENSQFFKDFFYP--LKPLEEEFEKIAVEIRERRMHRRRKYFLPV 231
VNA ++ IE + + K F L+ LE+ + +I + + +Y LP
Sbjct: 200 VNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRIE-PLPKHDTAPANRYALP- 257
Query: 232 DGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELV 291
DG + + FC C R RLTADG CL I++ PLR GA+ +LV
Sbjct: 258 DGTTFG---IIASTTEPFCATCDRSRLTADGLWLHCLYAISG-INLREPLRAGATHDDLV 313
Query: 292 D 292
+
Sbjct: 314 E 314
>emb|CAA76291.1| (Y16569) moaA [Mycobacterium tuberculosis]
Length = 378
Score = 145 bits (361), Expect = 9e-34
Identities = 113/305 (37%), Positives = 155/305 (50%), Gaps = 18/305 (5%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQ---LDGERTMKPEEIERIVRIASRLGIKKV 60
DR GR + +LR+S+ +CNL C YC E + L + +EI IV +G+ K+
Sbjct: 39 DRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKI 98
Query: 61 KLTGGEPTIRKDIVEIIRRIRPYV------VDLSLTTNGTTLYTLAEELKEAGLDRVNIS 114
+LTGGEP IR D+ II I V DL++TTNG L A +LK AG+ R+ IS
Sbjct: 99 RLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITIS 158
Query: 115 LDTLDRKKYKMITGFDVLDQVIKGIEK-ATKLFYPVKLNMVVMRGINDDEIWDLIRFAGK 173
LDTL ++K I+ +VI+GIE A F KL+ VV+RG NDDE+ DLI FA
Sbjct: 159 LDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARN 218
Query: 174 VNAILQLIEIEVPREMENSQFFKDFFYP--LKPLEEEFEKIAVEIRERRMHRRRKYFLPV 231
VNA ++ IE K F L L +++ IA + + +Y LP
Sbjct: 219 VNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAA-LPKYDSAPANRYRLP- 276
Query: 232 DGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGPLRNGASDAELV 291
DG + + FC C R RLTADG CL I++ +R GAS ++V
Sbjct: 277 DGTTFGIIASTT---EPFCATCDRSRLTADGIWLHCLYALSG-INLRESVRAGASANDVV 332
Query: 292 DIFKR 296
I +R
Sbjct: 333 QILQR 337
>dbj|BAB06245.1| (AP001515) molybdopterin cofactor biosynthesis [Bacillus
halodurans]
Length = 338
Score = 144 bits (359), Expect = 1e-33
Identities = 102/312 (32%), Positives = 164/312 (51%), Gaps = 38/312 (12%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQ-------LDGERTMKPEEIERIVRIASR 54
+ DR RP +LRIS+T CN C YC L + EE R+V + +
Sbjct: 6 MTDRLNRPFRDLRISVTDRCNFRCHYCMPADIFGPDYPFLKKTEILSFEETNRLVHLFHQ 65
Query: 55 LG-IKKVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRV 111
IKK+++TGGEP +RKD+ ++I + + D+++TTNGT L +A++LK+AGL RV
Sbjct: 66 TSPIKKIRITGGEPLMRKDVDQLISMLTATTGIEDVAMTTNGTLLPKMADKLKKAGLKRV 125
Query: 112 NISLDTLDRKKYKMITGFDV-LDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRF 170
+SLD+L+ +++ I G + V+ G+E A + VK+NMVV +G+ND ++ + +F
Sbjct: 126 TVSLDSLEDEQFGKINGRGIGTKPVLDGMEAAKEAGLGVKVNMVVQKGVNDQDVLPMAQF 185
Query: 171 AGKVNAILQLIE-IEVPR----EMENSQFFKDFF------YPLKPLEEEFE-KIAVEIRE 218
+ L+ IE ++V M++ +D +PL+P++ E+ ++A R
Sbjct: 186 FKEKGYTLRFIEYMDVGNSNGWRMDDVVAKRDILEMIHKVHPLEPVDPEYPGEVATRYRY 245
Query: 219 RRMHRRRKYFLPVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDIL 278
+ G VE+ V+ S+ FC C R RL+ +G L TCL D
Sbjct: 246 K-------------GTSVEIGVISSV-TDAFCTTCNRARLSVEGKLYTCLFATKG-HDFR 290
Query: 279 GPLRNGASDAEL 290
LR+GASD E+
Sbjct: 291 ELLRSGASDEEI 302
>pir||B83162 molybdopterin biosynthetic protein A1 PA3870 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9950049|gb|AAG07257.1|AE004804_5 (AE004804)
molybdopterin biosynthetic protein A1 [Pseudomonas
aeruginosa]
Length = 329
Score = 142 bits (355), Expect = 4e-33
Identities = 105/302 (34%), Positives = 154/302 (50%), Gaps = 20/302 (6%)
Query: 3 IDRFGRPVTNLRISLTKECNLNCFYCHREGQ--LDGERTMKPEEIERIVRIASRLGIKKV 60
ID GR + LR+S+T C+ C YC E L ++ + EEIER+ R+ G++K+
Sbjct: 5 IDGQGRQIDYLRLSVTDRCDFRCVYCMAEDMRFLPRQQVLTLEEIERVARLFVAGGVRKL 64
Query: 61 KLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTL 118
+LTGGEP +R IV + R+ P + +L +T+NG+ L A L +AGL R+NISLDTL
Sbjct: 65 RLTGGEPLVRPGIVGLCERLAALPGLRELCMTSNGSQLVRYARPLYDAGLSRLNISLDTL 124
Query: 119 DRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNAI 177
D +++ IT LD+V+ GI+ A F +KLN VVM+G N DE+ L+ FA
Sbjct: 125 DPLRFRAITRNGELDKVLAGIDAAQAAGFRRIKLNAVVMKGRNADEVPALVDFAIARGLD 184
Query: 178 LQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVVE 237
+ IE E+P + + F + ++ A+ + +Y V+
Sbjct: 185 ISFIE-EMPLGQVGRERGESFCSSDEVRALIAQRHALLDSAEQSGGPARYVRLVEHPQTR 243
Query: 238 VEVVRSMHNTVFCMNCTRLRLTADGYLKTC-----------LLRRDDLIDILGPLRNGAS 286
+ + S H+ FC C RLRLT +G L C LLRR L D GPL
Sbjct: 244 IGFI-SPHSHNFCATCNRLRLTVEGRLLLCLGHEHSLDLRALLRRHPLHD--GPLLEAIG 300
Query: 287 DA 288
+A
Sbjct: 301 EA 302
>sp|Q9X5W3|MOAA_RHOCA MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A
>gi|4457225|gb|AAD21201.1| (AF128444) MoaA [Rhodobacter
capsulatus]
Length = 328
Score = 141 bits (353), Expect = 8e-33
Identities = 109/323 (33%), Positives = 163/323 (49%), Gaps = 46/323 (14%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQ--LDGERTMKPEEIERIVRIASRLGIKK 59
L D FGR V LR+S+T C+L C YC +E L + + EE++R LG++K
Sbjct: 6 LCDGFGRDVRYLRVSVTDRCDLRCSYCMKEDVTFLPRNQVLSLEELDR-------LGVRK 58
Query: 60 VKLTGGEPTIRKDIVEIIRRIRPYVV-----DLSLTTNGTTLYTLAEELKEAGLDRVNIS 114
+++TGGEP +R+ I + ++ +L+LTTNGT L A+ L E G+ RVN+S
Sbjct: 59 LRVTGGEPLVRRGIGTFFAAMGTHLRAGRLDELTLTTNGTQLAAHAQSLAECGVKRVNVS 118
Query: 115 LDTLDRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKV 174
LDTL +KY +T F ++QV GI A VKLN + ++G+NDDEI+ L +A
Sbjct: 119 LDTLQAEKYARLTRFGRIEQVFAGIAAAQAAGLRVKLNAMALKGVNDDEIFALTDWAAAH 178
Query: 175 NAILQLIEI----EVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLP 230
+ L IE+ ++P QF+ PL++ + +E R R + L
Sbjct: 179 HCDLTFIELMPMGDIPAGTRLDQFW--------PLDD--VRAHLETRFRLIDNG----LN 224
Query: 231 VDGKVVEVEVVRS----------MHNTVFCMNCTRLRLTADGYLKTCLLRRDDLIDILGP 280
G V V ++ HN FC +C R+RLT G L TC L ++ D+
Sbjct: 225 TGGPARYVTVAQTGQRIGFISPLSHN--FCTSCNRVRLTCKGELYTC-LGQEGSSDLRPV 281
Query: 281 LRNGASDAELVDIFKRAVLMRRP 303
LR G + E + RA + R+P
Sbjct: 282 LRAGV-EGEALAREIRAAIARKP 303
>sp|Q56211|MOAA_SYNP7 MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A
>gi|1480154|emb|CAA67948.1| (X99625) moaA [Synechococcus
sp.]
Length = 327
Score = 138 bits (343), Expect = 1e-31
Identities = 92/277 (33%), Positives = 155/277 (55%), Gaps = 15/277 (5%)
Query: 1 MLIDRFGRPVTNLRISLTKECNLNCFYCHREGQ-LDGERT--MKPEEIERIVRIASRLGI 57
+L D R LR+SLT CN C YC +GQ LD +R + EI ++ LGI
Sbjct: 3 VLADHHDRQFRYLRLSLTDVCNFRCGYCLPKGQQLDPQRPALLTLPEIRHLIEGFVALGI 62
Query: 58 KKVKLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISL 115
+KV+LTGGEPT+R D+V+I+R + P + ++LT+NG L +L+ AGL ++N+SL
Sbjct: 63 EKVRLTGGEPTLRSDLVDIVRAVAAVPGIRRVALTSNGWNLRDRLADLQAAGLTQLNLSL 122
Query: 116 DTLDRKKYKMITGFDVLDQVIKGIEKATKLFYPV-KLNMVVMRGINDDEIWDLIRFAGKV 174
D+LD +++ ITG + V+ +E+A L P+ K+N V+++ +N ++ D + F
Sbjct: 123 DSLDAARFQAITGSSRFEAVMAALEQAIALRLPILKVNAVLLKTLNYPQLSDFVEFVR-- 180
Query: 175 NAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVE--IRERRMHRRRKYFLP-V 231
+ + + IE+ + ++N +F+ F L E++ + R+R ++Y P
Sbjct: 181 DRPISIRFIELMQTLDNHDYFQQEFLSGSVLTEQWLAQGWQPIKRDRTAGPAQEYCHPNY 240
Query: 232 DGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCL 268
GK+ + + ++ FC NC RLR+T+ G L+ CL
Sbjct: 241 QGKL----GIIAPYSPNFCQNCNRLRVTSRGALRLCL 273
>sp|Q55369|MOAA_SYNY3 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A >gi|7429626|pir||S75716
molybdenum cofactor biosynthesis protein A -
Synechocystis sp. (strain PCC 6803)
>gi|1001211|dbj|BAA10451.1| (D64003) molybdenum cofactor
biosynthesis protein A [Synechocystis sp.]
Length = 327
Score = 137 bits (341), Expect = 2e-31
Identities = 90/287 (31%), Positives = 150/287 (51%), Gaps = 29/287 (10%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERT--MKPEEIERIVRIASRLGIKK 59
L+D +GR + LR+SLT +CNL C YC + E++ + +E I+ LG+++
Sbjct: 18 LVDSYGRRIRKLRVSLTDQCNLRCHYCMPVDAIFLEQSSYLSCQEYGEIIGELIALGLEE 77
Query: 60 VKLTGGEPTIRKDIVEIIRRIRPYVVD-LSLTTNGTTLYTLAEELKEAGLDRVNISLDTL 118
V+LTGGEP +R++ EI+R I + + LTTNG L + L E + +N+SLD+L
Sbjct: 78 VRLTGGEPLLRRNFTEIVRAIGQLKLKKIGLTTNGIVLDRHLDTLGENNVLDLNVSLDSL 137
Query: 119 DRKKYKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAIL 178
+ K + IT + L+ +++ +E A++ + +KLN VVMR IND EI+DLI +A + +
Sbjct: 138 NAKTFSEITHRNCLNTILRNLELASRQGFKIKLNTVVMREINDREIFDLIEYAKRWEMEI 197
Query: 179 QLIEIE----VPREMENSQFFKDFF-------YPLKPLEEEFEKIAVEIRERRMHRRRKY 227
+ +EI R E + Y LKP++ + A +Y
Sbjct: 198 RFLEIMRIGYACRHQEKTFISAQELLAKIQQKYSLKPIQSALDATAF-----------RY 246
Query: 228 FLPVDGKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRDDL 274
G + + + + FC +C+R RL+ DG L+ CLL+ + +
Sbjct: 247 STSCGGIIGFI----ASESQPFCGHCSRWRLSVDGTLRACLLKNEGI 289
>gb|AAB84030.1| (AF027213) molybdopterin cofactor biosynthetic protein [Aspergillus
nidulans]
Length = 694
Score = 134 bits (333), Expect = 2e-30
Identities = 107/303 (35%), Positives = 158/303 (51%), Gaps = 29/303 (9%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEI---ERIVRIASRL--- 55
L D F R LRIS+T+ CNL C YC E +G P + IV ++S
Sbjct: 85 LTDTFNRQHDYLRISVTERCNLRCLYCMPE---EGVPLSPPAHVLTSPEIVYLSSLFVSQ 141
Query: 56 GIKKVKLTGGEPTIRKDIVEIIRRIRPY----VVDLSLTTNGTTLYTLAEELKEAGLDRV 111
G+ K++LTGGEPT+RKDIV +++ I + +L LTTNG +L+ E + EAGL V
Sbjct: 142 GVTKIRLTGGEPTVRKDIVPLMQSIGELRHHGLRELCLTTNGISLHRKLEPMVEAGLTGV 201
Query: 112 NISLDTLDRKKYKMIT---GFDVLDQVIKGIEKATKLFYPVKL--NMVVMRGINDDEIWD 166
N+SLDTLD +++++T GFD + + I I++ K+ +KL N VVMRG+N+ EI
Sbjct: 202 NLSLDTLDPFQFQIMTRRKGFDAVMKSIDRIQELNKMGAGIKLKINCVVMRGLNEREIIP 261
Query: 167 LIRFAGKVNAILQLIEIEVPREMENSQFFKDFFYP--LKPLEEEFEKIAVEIRERRMHRR 224
+ ++ IE +P + K Y L + E++ + ++ + +
Sbjct: 262 FVEMGRDSPIEVRFIEY-MPFDGNKWSKGKMVSYQEMLALIREKYPTLE-KVVDHKNDTS 319
Query: 225 RKYFLPVDGKVVEVEVVRSM-HNTVFCMNCTRLRLTADGYLKTCLLRRDD--LIDILGPL 281
+ Y +P G V + SM HN FC C RLR+T DG LK CL + L DI+
Sbjct: 320 KTYRIP--GFQGRVGFITSMTHN--FCGTCNRLRITCDGNLKVCLFGNSEVSLRDIIRQQ 375
Query: 282 RNG 284
NG
Sbjct: 376 NNG 378
>sp|P45311|MOAA_HAEIN MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A >gi|1075029|pir||B64136
molybdenum cofactor biosynthesis protein A - Haemophilus
influenzae (strain Rd KW20) >gi|1574526|gb|AAC23321.1|
(U32840) molybdenum cofactor biosynthesis protein A
(moaA) [Haemophilus influenzae Rd]
Length = 337
Score = 132 bits (330), Expect = 4e-30
Identities = 88/286 (30%), Positives = 151/286 (52%), Gaps = 13/286 (4%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREG---QLDGERTMKPEEIERIVRIASRLGIK 58
L+D F R LR+S+T +CN C YC +G + + + +EI + + + +G +
Sbjct: 14 LVDPFQRQYYYLRLSITDQCNFRCTYCLPDGYQPEANKPSFLTLKEITHLAQAFAEMGTE 73
Query: 59 KVKLTGGEPTIRKDIVEIIRRIRPY--VVDLSLTTNGTTLYTLAEELKEAGLDRVNISLD 116
K++LTGGEPT+RKD + I I + L++TTNG + + K+AG+ +N+S+D
Sbjct: 74 KIRLTGGEPTLRKDFISIAESITNIDGIRQLAVTTNGYRMAKDVADWKKAGITSINVSVD 133
Query: 117 TLDRKKYKMITGFDVLDQVIKGIEKATKLFY-PVKLNMVVMRGINDDEIWDLIRFAGKVN 175
+LD K + ITG + D V++GI++A ++ Y VK+N V+M+ +ND E + +
Sbjct: 134 SLDPKMFHQITGINKFDDVMRGIDRAFEVGYNKVKVNSVLMKNLNDKEFEQFLAWVKDRP 193
Query: 176 AILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRER-RMHRRRKYFLPVDGK 234
++ IE+ EM++ FF F + L ++ K ++ + K F D
Sbjct: 194 IQMRFIELMQTGEMDS--FFDKFHLSGQVLADKLLKNGWTLQHKSHTDGPAKVFTHPD-Y 250
Query: 235 VVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCLLRRD--DLIDIL 278
E+ ++ FC +C RLR++A G L CL + +L D+L
Sbjct: 251 AGEIGLIMPYEKN-FCASCNRLRVSAKGKLHLCLFGEEGIELRDLL 295
>sp|P30745|MOAA_ECOLI MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A >gi|321842|pir||S31879
molybdenum cofactor biosynthesis protein A - Escherichia
coli >gi|42008|emb|CAA49861.1| (X70420) moaA
[Escherichia coli] >gi|1651354|dbj|BAA35439.1| (D90716)
Molybdenum cofactor biosynthesis protein A. [Escherichia
coli] >gi|1786999|gb|AAC73868.1| (AE000181)
molybdopterin biosynthesis, protein A [Escherichia coli
K12]
Length = 329
Score = 129 bits (321), Expect = 4e-29
Identities = 89/276 (32%), Positives = 146/276 (52%), Gaps = 14/276 (5%)
Query: 2 LIDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKP----EEIERIVRIASRLGI 57
L D F R LR+S+T CN C YC +G T K +EI R+ R +RLG
Sbjct: 5 LTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFARLGT 64
Query: 58 KKVKLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISL 115
+KV+LTGGEP++R+D +II +R + +++TTNG L ++AGL +N+S+
Sbjct: 65 EKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVASWRDAGLTGINVSV 124
Query: 116 DTLDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKV 174
D+LD +++ ITG D +QV+ GI+ A + F VK+N V+MR +N ++ + +
Sbjct: 125 DSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWI--Q 182
Query: 175 NAILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIA--VEIRERRMHRRRKYFLPVD 232
+ +QL IE+ E S+ F+ + L +E + ++R+R + + P
Sbjct: 183 HRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHP-- 240
Query: 233 GKVVEVEVVRSMHNTVFCMNCTRLRLTADGYLKTCL 268
E+ ++ + FC C RLR+++ G L CL
Sbjct: 241 DYAGEIGLIMP-YEKDFCATCNRLRVSSIGKLHLCL 275
>emb|CAA75545.1| (Y15252) molybdopterin co-factor synthesis protein [Pseudomonas
aeruginosa]
Length = 184
Score = 128 bits (318), Expect = 1e-28
Identities = 74/174 (42%), Positives = 107/174 (60%), Gaps = 5/174 (2%)
Query: 3 IDRFGRPVTNLRISLTKECNLNCFYCHREGQ--LDGERTMKPEEIERIVRIASRLGIKKV 60
ID GR + LR+S+T C+ C YC E L ++ + EEIER+ R+ G++K+
Sbjct: 5 IDGQGRQIDYLRLSVTDRCDFRCVYCMAEDMRFLPRQQVLTLEEIERVARLFVAGGVRKL 64
Query: 61 KLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTL 118
+LTGGEP +R IV + R+ P + +L +T+NG+ L A L +AGL R+NISLDTL
Sbjct: 65 RLTGGEPLVRPGIVGLCERLAALPGLRELCMTSNGSQLVRYARPLYDAGLSRLNISLDTL 124
Query: 119 DRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFA 171
D +++ IT LD+V+ GI+ A F +KLN VVM+G N DE+ L+ FA
Sbjct: 125 DPLRFRAITRNGELDKVLAGIDAAQAAGFRRIKLNAVVMKGRNADEVPALVDFA 178
>pir||F82250 molybdenum cofactor biosynthesis protein A VC1024 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9655487|gb|AAF94183.1| (AE004184) molybdenum
cofactor biosynthesis protein A [Vibrio cholerae]
Length = 334
Score = 116 bits (287), Expect = 4e-25
Identities = 86/272 (31%), Positives = 139/272 (50%), Gaps = 10/272 (3%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERT----MKPEEIERIVRIASRLGIKK 59
DRF R LR+S+T CN C YC +G + EI R+V + G K
Sbjct: 12 DRFQRKFYYLRLSITDVCNFKCTYCLPDGYKPSAGRPASFLTVNEIRRVVSAFAHCGTSK 71
Query: 60 VKLTGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDT 117
V++TGGEP++RKD EII I P + ++ TTNG L E +EAGL ++N+S+D+
Sbjct: 72 VRITGGEPSLRKDFGEIIHTIAQTPGIQKVATTTNGYRLAKHIGEWREAGLTQLNVSVDS 131
Query: 118 LDRKKYKMITGFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGKVNA 176
LD + + ITG + QV+ GI++A ++ F VK+N+V+M+ +N E+ + +
Sbjct: 132 LDPRMFAQITGENRFQQVMSGIDRAFEVGFEQVKVNVVLMKNLNHLELPQFMAWIKTRPI 191
Query: 177 ILQLIEIEVPREMENSQFFKDFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLPVDGKVV 236
L+ IE+ EM+ + F + + + F + + F+ D +
Sbjct: 192 QLRFIELMQTGEMD-ALFARHHVSGISIRDYLFGNGWLLKARADNDGPAQVFIHPDFQ-G 249
Query: 237 EVEVVRSMHNTVFCMNCTRLRLTADGYLKTCL 268
E+ ++ + FC +C RLR++A G L CL
Sbjct: 250 EIGLIMP-YEKDFCRSCNRLRVSALGKLHLCL 280
>sp|Q50746|MOAA_METTM PUTATIVE MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A
>gi|1361913|pir||S57481 molybdopterin biosynthesis
protein moaA - Methanobacterium thermoautotrophicum
(strain Marburg) (fragment) >gi|2127701|pir||S63553
moaA protein - Methanobacterium thermoautotrophicum
(fragment) >gi|871467|emb|CAA61207.1| (X87968) putative
[Methanobacterium thermoautotrophicum]
Length = 87
Score = 98.7 bits (242), Expect = 8e-20
Identities = 43/77 (55%), Positives = 58/77 (74%)
Query: 4 DRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVKLT 63
D RP+ +LRIS+T CN++C YCHR+G L + M PE+IE I R+AS LG+KK++L+
Sbjct: 5 DNHRRPLVSLRISVTGRCNVSCIYCHRDGILRSDEEMSPEDIENICRVASDLGVKKIRLS 64
Query: 64 GGEPTIRKDIVEIIRRI 80
GGEP IR DIVEI+ +I
Sbjct: 65 GGEPLIRDDIVEIVEKI 81
>pir||G71040 hypothetical protein PH1615 - Pyrococcus horikoshii
>gi|3258044|dbj|BAA30727.1| (AP000006) 420aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 420
Score = 84.7 bits (206), Expect = 1e-15
Identities = 83/267 (31%), Positives = 133/267 (49%), Gaps = 31/267 (11%)
Query: 2 LIDRFGRPVTNL-RISLTKECNLNCFYCH-REGQLDGERTMK-PEEIERIVRIASRLGIK 58
LIDR TNL ++ + CN++C +C EG R + +I+ +++ + + +
Sbjct: 109 LIDRG----TNLIQVRGSTGCNMSCIFCSVDEGPYSRTRKLDFVVDIDYLMKWFNLVAKE 164
Query: 59 KVKL------TGGEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYT-LAEELKEAGLD 109
K K GEP + IVE+++ +R P+V +S+ +NG L L EEL EAGLD
Sbjct: 165 KGKGLEAHLDAQGEPLMYPFIVELVQALRDHPHVSVISMQSNGVLLDDKLVEELAEAGLD 224
Query: 110 RVNISLDTLDRKKYKMITGFDVLD--QVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDL 167
RVN+S+ +LD KK KM+ G D V++ E V + V++ GINDDE
Sbjct: 225 RVNLSIHSLDPKKAKMLMGIKDYDLSHVLEMAEALVNAGIDVLIAPVIIFGINDDEAEAF 284
Query: 168 IRFAGKVNAILQL----IEIEVPREMENSQF------FKDFFYPLKPLEEEFEKIAVEIR 217
I FA K+ A + + VP + + FK+F+ L+ LEE+ + ++
Sbjct: 285 IEFARKIGAGKRWPALGFQNYVPYKFGRNPVIAKPISFKEFYEWLRKLEEKTGMKPLVLK 344
Query: 218 ERRMHRRRKYFLPV---DGKVVEVEVV 241
+ F+P+ G+VV+ EVV
Sbjct: 345 PHHFGMHPRPFIPLAFKRGEVVKAEVV 371
>pir||H69210 conserved hypothetical protein MTH831 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621921|gb|AAB85329.1| (AE000860) molybdenum
cofactor biosynthesis MoaA homolog [Methanobacterium
thermoautotrophicum]
Length = 497
Score = 81.9 bits (199), Expect = 9e-15
Identities = 55/167 (32%), Positives = 87/167 (51%), Gaps = 12/167 (7%)
Query: 15 ISLTKECNLNCFYCHREGQLDG---ERTMKPEEIERIVRIASR---LGIKKVKLTGGEPT 68
I +T CNL C C + E T EEI ++R R + ++ GGEPT
Sbjct: 97 IDVTNRCNLKCPICFANAAVSNYIYEPTY--EEIREMLRNLRRNRPVPTPAIQYAGGEPT 154
Query: 69 IRKDIVEIIRRIRPY-VVDLSLTTNGTTLYT---LAEELKEAGLDRVNISLDTLDRKKYK 124
+RKDIV++++ R + + TNG L LA EL+EAGL+ V + D + + Y
Sbjct: 155 VRKDIVDLVKLAREEGFTHVQIATNGVRLARKPELAAELREAGLNTVYLQFDGVTEEPYI 214
Query: 125 MITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFA 171
G ++L ++ IE K+ + L ++RG+ND+++ D+IRFA
Sbjct: 215 TSRGKNLLPIKLQAIENCRKVGLGIVLVPTLVRGLNDNQVGDIIRFA 261
>pir||B75174 molybdenum cofactor biosynthesis protein A related PAB1998 -
Pyrococcus abyssi (strain Orsay)
>gi|5457983|emb|CAB49473.1| (AJ248284) MOLYBDENUM
COFACTOR BIOSYNTHESIS PROTEIN A related [Pyrococcus
abyssi]
Length = 419
Score = 81.5 bits (198), Expect = 1e-14
Identities = 80/271 (29%), Positives = 132/271 (48%), Gaps = 39/271 (14%)
Query: 2 LIDRFGRPVTNL-RISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLG---- 56
LIDR TNL ++ + CN+ C +C +D + +++ +V I L
Sbjct: 109 LIDRG----TNLIQVRGSTGCNMRCIFC----SVDEGPYSRTRKLDFVVDIDYLLKWFDW 160
Query: 57 IKKVKLTG--------GEPTIRKDIVEIIRRIR--PYVVDLSLTTNGTTLYT-LAEELKE 105
+ K K G GEP + IVE+++ +R P+V +S+ +NG L L EEL E
Sbjct: 161 VAKEKGKGLEAHLDAQGEPLLYPFIVELVQALREHPHVSVISMQSNGVLLNDKLVEELAE 220
Query: 106 AGLDRVNISLDTLDRKKYKMITGFD--VLDQVIKGIEKATKLFYPVKLNMVVMRGINDDE 163
AGLDRVN+S+ +LD +K KM+ G L+ V++ E V + V+M G+NDDE
Sbjct: 221 AGLDRVNLSIHSLDPEKAKMLMGIKDYDLNHVLEMAEALVNAGIDVLIAPVIMFGVNDDE 280
Query: 164 IWDLIRFAGKVNAILQL----IEIEVPREMENSQF------FKDFFYPLKPLEEEFEKIA 213
I FA ++ A + + +P + + FK+F+ L+ LEE+
Sbjct: 281 AEAFIEFARRIGAGKRWPALGFQNYIPYKFGRNPVIAKPVPFKEFYRWLRELEEKTGMKP 340
Query: 214 VEIRERRMHRRRKYFLPV---DGKVVEVEVV 241
+ ++ + F+P+ G+VV+ EV+
Sbjct: 341 LILKPHHFGMYPRPFIPLAFKRGEVVKAEVI 371
>gi|11499897 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7451255|pir||D69539 conserved hypothetical protein
AF2316 - Archaeoglobus fulgidus
>gi|2648203|gb|AAB88940.1| (AE000944) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 518
Score = 80.8 bits (196), Expect = 2e-14
Identities = 68/213 (31%), Positives = 109/213 (50%), Gaps = 25/213 (11%)
Query: 13 LRISLTKECNLNCFYCHREGQLDG---ERTMKPEEIERIVRIASRL---GIKKVKLTGGE 66
L I LT C+L C+YC + G E T+ E+I +VR A + G V+LTGGE
Sbjct: 102 LNIVLTNRCDLACWYCFFYARRAGYVYEPTI--EQIREMVRKAKNMKPIGCNAVQLTGGE 159
Query: 67 PTIRKDIVEIIRRIRPYVVD-LSLTTNGTTLY---TLAEELKEAGLDRVNISLDTLDRKK 122
PT+R D+++IIR I+ D + L TNG L A ++ AG++ V +S D +D K
Sbjct: 160 PTLRDDLIDIIRMIKEEGYDHIQLNTNGIRLAEDPDFALRVRVAGVNTVYLSFDGVDEK- 218
Query: 123 YKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQLIE 182
T ++ K +E + + L V++G+ND ++ D+IRFA + I++ +
Sbjct: 219 ----TNPKNHHEIPKILENCRRAQLGLVLVPTVIKGVNDHQLGDIIRFAAENIDIVRGVN 274
Query: 183 IE-------VPREMENSQFFKDFFYPLKPLEEE 208
+ +PR+ E QF +K +EE+
Sbjct: 275 FQPVSLVGSMPRK-EREQFRITIPDCIKAIEEQ 306
>sp|Q58036|Y619_METJA HYPOTHETICAL PROTEIN MJ0619 >gi|2128410|pir||C64377 hypothetical
protein MJ0619 - Methanococcus jannaschii
>gi|1591330|gb|AAB98614.1| (U67510) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 506
Score = 79.2 bits (192), Expect = 6e-14
Identities = 54/167 (32%), Positives = 88/167 (52%), Gaps = 9/167 (5%)
Query: 15 ISLTKECNLNCFYCHREGQLDGERTMKP--EEIERIVRIASRL--GIKKVKLTGGEPTIR 70
I +T CNLNC C G + +P E+I+R++ + ++ GGEPT+R
Sbjct: 92 IDVTNRCNLNCPICFANANKSG-KVYEPSFEDIKRMMENLRKEIPPTPAIQFAGGEPTVR 150
Query: 71 KDIVEIIRRIRPY-VVDLSLTTNGTTLYTL--AEELKEAGLDRVNISLDTLDRKKYKMIT 127
D+ E+I+ R + + L TNG L + ++LKEAGL + + D + K Y +
Sbjct: 151 SDLPELIKLARDMGFLHVQLATNGIKLKNINYLKKLKEAGLSTIYLQFDGISEKPYLVAR 210
Query: 128 GFDVLDQVIKGIEKATKL-FYPVKLNMVVMRGINDDEIWDLIRFAGK 173
G ++L K IE K+ F V L ++RG+ND+E+ +IR+A +
Sbjct: 211 GKNLLPIKQKVIENCKKVGFDSVVLVPTLVRGVNDNEVGGIIRYAAE 257
>gb|AAK41845.1| Coenzyme PQQ synthesis protein E (pqqE-3) [Sulfolobus solfataricus]
Length = 378
Score = 78.0 bits (189), Expect = 1e-13
Identities = 47/150 (31%), Positives = 80/150 (53%), Gaps = 4/150 (2%)
Query: 8 RPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVKLTGGEP 67
RPV +LT++CNL C +C+ +GE EE R++ + + I + ++GGEP
Sbjct: 35 RPVVTW--NLTRKCNLKCLHCYINASPEGEDGSTTEEALRLIDEMAEMRIPLIIMSGGEP 92
Query: 68 TIRKDIVEIIRRIRPYVVDLSLTTNGTTL-YTLAEELKEAGLDRVNISLDTLDRKKYKMI 126
+R+D E+ R + L+L+TNGT + ++A++LKE V ISLD+ D + +
Sbjct: 93 LMRRDFFELASYARIKGIKLALSTNGTLITESVAKKLKELDFSYVGISLDSYDPEFHDRF 152
Query: 127 TGFD-VLDQVIKGIEKATKLFYPVKLNMVV 155
G + + +KGI+ A + V L +
Sbjct: 153 RGLNGAFNMTVKGIKNAINVGLNVGLRFTI 182
>gb|AAK42035.1| Coenzyme PQQ synthesis protein E (pqqE-4) [Sulfolobus solfataricus]
Length = 378
Score = 75.7 bits (183), Expect = 7e-13
Identities = 46/150 (30%), Positives = 78/150 (51%), Gaps = 4/150 (2%)
Query: 8 RPVTNLRISLTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVKLTGGEP 67
RPV +LT++CNL C +C+ +GE + EE ++ + + I + ++GGEP
Sbjct: 35 RPVVTW--NLTRKCNLKCLHCYINASPEGEDGLTTEEALGLIDEMAEMKIPLIIMSGGEP 92
Query: 68 TIRKDIVEIIRRIRPYVVDLSLTTNGTTL-YTLAEELKEAGLDRVNISLDTLDRKKYKMI 126
+R+D E+ R + L+L+TNGT + ++A+ LKE V ISLD+ D + +
Sbjct: 93 LMRRDFFELASYARSKGIKLALSTNGTLISESVAKRLKELDFSYVGISLDSYDPEFHDKF 152
Query: 127 TGFD-VLDQVIKGIEKATKLFYPVKLNMVV 155
G + + +KGI A + V L +
Sbjct: 153 RGLNGAFNMTVKGIGNAINVGLNVGLRFTI 182
>emb|CAC11421.1| (AL445063) molybdenum cofactor synthesis-step 1 (MOCS1) related
protein [Thermoplasma acidophilum]
Length = 310
Score = 75.7 bits (183), Expect = 7e-13
Identities = 60/222 (27%), Positives = 102/222 (45%), Gaps = 22/222 (9%)
Query: 21 CNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVKLTGGEPTIRKDIVEIIRRI 80
CNL C C+ G+ ++I++ ++ GIK V +TGGEPT+ K++V+IIR++
Sbjct: 9 CNLRCKSCNA---WQGKIFFPEDQIDKHLQEMKNNGIKIVSVTGGEPTLNKNVVDIIRKL 65
Query: 81 RPYVVDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDRKKYKMITGFDVLDQVIKGIE 140
+ + TNGT Y L + LD V ISLD+ +++ G + D V+ I+
Sbjct: 66 KENHFFTHIATNGTNPYVLRKLYPY--LDAVTISLDSNIPEEHNAYRGLKIFDTVVSNIK 123
Query: 141 KATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAILQLIEIEVPREM----ENSQFFK 196
+A V NM+V N ++ ++ FA E+ VP M +++ +F+
Sbjct: 124 EAKSKVKIVTANMLV-TNFNYFKVGEIADFANN--------ELGVPLSMCFPEQDAYYFQ 174
Query: 197 DFFYPLKPLEEEFEKIAVEIRERRMHRRRKYFLP----VDGK 234
DF + + F + R Y+ +DGK
Sbjct: 175 DFQVTNDMIRQAFSYAYENYHKHVFGNMRSYYKEAVDFIDGK 216
>sp|Q57567|Y103_METJA HYPOTHETICAL PROTEIN MJ0103 >gi|2128126|pir||G64312 hypothetical
protein MJ0103 - Methanococcus jannaschii
>gi|1498868|gb|AAB98083.1| (U67467) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 433
Score = 73.4 bits (177), Expect = 3e-12
Identities = 76/268 (28%), Positives = 127/268 (47%), Gaps = 50/268 (18%)
Query: 21 CNLNCFYCH-REGQLDGERTMKP--------EEIERIVRIASRLGIKKVKLTGGEPTIRK 71
CNLNC +C EG+ R E ++IV I+ GEP++
Sbjct: 118 CNLNCIFCSVDEGEFSKTRKNDYYVDLEYLIENYKKIVDFKENKFIEAHLDGQGEPSLYY 177
Query: 72 DIVEIIRRIRPYVVD----LSLTTNGTTL-YTLAEELKEAGLDRVNISLDTLDRKKYKMI 126
+V++++ + +S+ TNGT L Y L +EL+EAGL R+N+S++ LD K KM+
Sbjct: 178 PLVDLVQELAEINKKGNGIVSMQTNGTVLNYKLIDELEEAGLHRINLSINALDEKMAKML 237
Query: 127 TGFDVLDQVIKGIEKATKLFYPVKLNMVV----MRGINDDEIWDLIRFA----------- 171
+G D IK I + K+++++ + IND+E +I +A
Sbjct: 238 SG--RRDYNIKKILDIAEYIKNSKIHLLIAPLLLPNINDEEFKRVIEYAVDLEQKNPQNI 295
Query: 172 -----GKVNAIL--QLIEI----EVPREMENSQFFKDFFYPLKPLEEEFEKIAVEI---- 216
GK + IL QL + P++M+ F K F+Y L E E++K +E+
Sbjct: 296 INPLTGKKDPILGCQLCRVYQLGRRPKKMKVWDFEK-FYYLLGKYELEYKKKGIEVKLIT 354
Query: 217 --RERRMHRRRKYFLPVD-GKVVEVEVV 241
++ H+R++ P G+V +V+VV
Sbjct: 355 SPKDFGTHKRKRLPYPFKVGEVTKVKVV 382
>pir||D64400 hypothetical protein MJ0804 - Methanococcus jannaschii
Length = 286
Score = 72.6 bits (175), Expect = 6e-12
Identities = 51/162 (31%), Positives = 86/162 (52%), Gaps = 23/162 (14%)
Query: 15 ISLTKECNLNCFYCHREGQLDGERTMKP------EEIERIVRIASRLGIKKVKLTGGEPT 68
I LT++CNLNC YC+ +T+K EE E + S+ G + L G
Sbjct: 44 IELTQKCNLNCIYCYSR-----LKTVKRGIYGNLEEAETVT--ISQYGEPLLDLEG---- 92
Query: 69 IRKDIVEIIRRIRPYVVDLSLTTNGTTLYT-LAEELKEAGLDRVNISLDTLDRKKYKMIT 127
+ + I + + + L TNGT L + +ELK+ GLD + ISL + R+KYK++T
Sbjct: 93 ----VKKAIEFCKDLGLRVDLQTNGTLLNEEIIKELKDLGLDLIMISLSSFSREKYKLLT 148
Query: 128 GFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIR 169
G D ++V+ I+ A+K + + + + + G ND+E+ +L +
Sbjct: 149 GKDYFNRVLNNIKIASKYLHTI-VRSIYIPGFNDNELLNLAK 189
>sp|Q58214|Y804_METJA HYPOTHETICAL PROTEIN MJ0804 >gi|2826326|gb|AAB98804.1| (U67525)
pyruvate formate-lyase activating enzyme (act)
[Methanococcus jannaschii]
Length = 286
Score = 72.6 bits (175), Expect = 6e-12
Identities = 51/162 (31%), Positives = 86/162 (52%), Gaps = 23/162 (14%)
Query: 15 ISLTKECNLNCFYCHREGQLDGERTMKP------EEIERIVRIASRLGIKKVKLTGGEPT 68
I LT++CNLNC YC+ +T+K EE E + S+ G + L G
Sbjct: 44 IELTQKCNLNCIYCYSR-----LKTVKRGIYGNLEEAETVT--ISQYGEPLLDLEG---- 92
Query: 69 IRKDIVEIIRRIRPYVVDLSLTTNGTTLYT-LAEELKEAGLDRVNISLDTLDRKKYKMIT 127
+ + I + + + L TNGT L + +ELK+ GLD + ISL + R+KYK++T
Sbjct: 93 ----VKKAIEFCKDLGLRVDLQTNGTLLNEEIIKELKDLGLDLIMISLSSFSREKYKLLT 148
Query: 128 GFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIR 169
G D ++V+ I+ A+K + + + + + G ND+E+ +L +
Sbjct: 149 GKDYFNRVLNNIKIASKYLHTI-VRSIYIPGFNDNELLNLAK 189
>gi|11498523 pyruvate formate-lyase activating enzyme (act-2) [Archaeoglobus
fulgidus] >gi|7450322|pir||F69364 pyruvate formate-lyase
activating enzyme (act-2) homolog - Archaeoglobus
fulgidus >gi|2649678|gb|AAB90319.1| (AE001040) pyruvate
formate-lyase activating enzyme (act-2) [Archaeoglobus
fulgidus]
Length = 283
Score = 71.0 bits (171), Expect = 2e-11
Identities = 65/195 (33%), Positives = 96/195 (48%), Gaps = 23/195 (11%)
Query: 9 PVTNLRISLTKECNLNCFYCH-REGQLDGERTMKPEEIERIVRIASRLGIKKVKLTG-GE 66
PV + +T CNL C +C+ R QL G KP L K + ++ GE
Sbjct: 34 PVHHPSYEVTPSCNLRCIFCYSRVAQLKGTAP-KPGYY-------GSLNPKAITISQYGE 85
Query: 67 PTI--RKDIVEIIRRIRPYV--VDLSLTTNGTTLYTLAEELKEAGLDRVNISLDTLDRKK 122
P + +VEIIR++R V + + TNGT L E+ + D V ISLD R+
Sbjct: 86 PFVVGTSRVVEIIRKLRERFGEVRIDIQTNGTLL---EPEILGSEADIVMISLDAGSRES 142
Query: 123 YKMITGFDVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNAI-LQLI 181
Y ITG D ++V+K IEK ++ Y V + V M GIND+E+ + A + + + LQ +
Sbjct: 143 YAEITGKDFFERVVKNIEKMSEHTYTV-VRTVFMPGINDEELERIAEIASQADELFLQPL 201
Query: 182 EIEVPREMENSQFFK 196
I EN++ K
Sbjct: 202 SI----YRENTELLK 212
>sp|P71517|PQQE_METEX COENZYME PQQ SYNTHESIS PROTEIN E >gi|2160686|gb|AAB58898.1|
(U72662) PqqE [Methylobacterium extorquens]
Length = 384
Score = 70.2 bits (169), Expect = 3e-11
Identities = 57/177 (32%), Positives = 85/177 (47%), Gaps = 5/177 (2%)
Query: 3 IDRFGRPVTNLRISLTKECNLNCFYCHREGQLDGERT-MKPEEIERIVRIASRLGIKKVK 61
+D PV L LT C L C YC +LD + + R++ A+ LG+ V
Sbjct: 11 VDVIPAPV-GLLAELTHRCPLRCPYCSNPLELDRRSAELDTQTWLRVLTEAAGLGVLHVH 69
Query: 62 LTGGEPTIRKDIVEIIRRIRPYVVDLSLTTNGT-TLYTLAEELKEAGLDRVNISLDTLDR 120
L+GGEPT R DIVEI + + +L T+G + L + GLD V +S+ +D
Sbjct: 70 LSGGEPTARPDIVEITAKCAELGLYSNLITSGVGGALAKLDALYDVGLDHVQLSVQGVDA 129
Query: 121 KKYKMITGF-DVLDQVIKGIEKATKLFYPVKLNMVVMRGINDDEIWDLIRFAGKVNA 176
+ I G + Q ++ + T+L P+ LN V+ RG N E+ I A K+ A
Sbjct: 130 ANAEKIGGLKNAQPQKMQFAARVTELGLPLTLNSVIHRG-NIHEVPGFIDLAVKLGA 185
>gi|11499591 heme biosynthesis protein (nirJ-2) [Archaeoglobus fulgidus]
>gi|7483317|pir||H69500 heme biosynthesis protein
(nirJ-2) homolog - Archaeoglobus fulgidus
>gi|2648528|gb|AAB89245.1| (AE000964) heme biosynthesis
protein (nirJ-2) [Archaeoglobus fulgidus]
Length = 468
Score = 69.9 bits (168), Expect = 4e-11
Identities = 42/143 (29%), Positives = 74/143 (51%), Gaps = 3/143 (2%)
Query: 17 LTKECNLNCFYCHREGQLDGERTMKPEEIERIVRIASRLGIKKVKLTGGEPTIRKDIVEI 76
+T CNL C +C+ + + +E + RLG+ + +GGEP +R+DI E+
Sbjct: 120 ITYSCNLRCKHCYATAGKPLQDELTTDEALETIDKLDRLGVTIIAFSGGEPLVRRDIFEL 179
Query: 77 IRRIRPYVVDLSLTTNGTTL-YTLAEELKEAGLDRVNISLDTLDRKKYKMITGF-DVLDQ 134
R + +++ TNGT + +A+ +KE G+ V ISLD + ++ ++ G D+
Sbjct: 180 TRYAAEKGIYVAIATNGTLITEEIAKRMKENGVGYVQISLDGM-KETHEAFRGIRGCFDK 238
Query: 135 VIKGIEKATKLFYPVKLNMVVMR 157
++GI A K V ++M V R
Sbjct: 239 TVEGIRNAVKTGLFVNVSMTVTR 261
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.325 0.143 0.418
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107772972
Number of Sequences: 2977
Number of extensions: 4380456
Number of successful extensions: 16135
Number of sequences better than 1.0e-10: 56
Number of HSP's better than 0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 15940
Number of HSP's gapped (non-prelim): 68
length of query: 306
length of database: 189,106,746
effective HSP length: 53
effective length of query: 253
effective length of database: 157,386,935
effective search space: 39818894555
effective search space used: 39818894555
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.6 bits)
S2: 165 (68.7 bits)