BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2277 (guaB-like2) DE:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE RELATED (136 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75197 yhcV homolog PAB2277 - Pyrococcus abyssi (strain Ors... 265 1e-70 pir||A71231 yhcV homolog PH0107 - Pyrococcus horikoshii >gi|3256... 235 1e-61 sp|P54606|YHCV_BACSU HYPOTHETICAL 14.9 KD PROTEIN IN CSPB-GLPP I... 81 6e-15 sp|P32987|YBP3_ACIAM HYPOTHETICAL 17.7 KD PROTEIN IN BPS2 3'REGI... 78 5e-14 gb|AAK43272.1| Conserved hypothetical protein [Sulfolobus solfat... 77 9e-14 dbj|BAB07461.1| (AP001519) unknown conserved protein in others [... 77 9e-14 pir||A72481 yhcV homolog APE2489 - Aeropyrum pernix (strain K1) ... 75 3e-13 gb|AAK43324.1| Conserved hypothetical protein [Sulfolobus solfat... 74 6e-13 pir||E72569 yhcV homolog APE1838 - Aeropyrum pernix (strain K1) ... 73 1e-12 sp|Q58069|Y653_METJA HYPOTHETICAL PROTEIN MJ0653 >gi|2128024|pir... 73 1e-12 gb|AAK42712.1| Hypothetical protein [Sulfolobus solfataricus] 72 2e-12 sp|O58045|IMDH_PYRHO INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP... 71 4e-12 pir||G69030 MJ0653 homolog MTH1226 - Methanobacterium thermoauto... 71 5e-12 pir||D71451 MJ0653 homolog PH0267 - Pyrococcus horikoshii >gi|32... 71 5e-12 pir||H72290 conserved hypothetical protein - Thermotoga maritima... 71 5e-12 sp|P42851|IMDH_PYRFU INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP... 70 9e-12 sp|Q57892|Y450_METJA HYPOTHETICAL PROTEIN MJ0450 >gi|2128329|pir... 70 9e-12 pir||E75015 IMP dehydrogenase (EC 1.1.1.205) PAB1250 - Pyrococcu... 70 9e-12 pir||F72730 yhcV homolog APE0383 - Aeropyrum pernix (strain K1) ... 70 1e-11 pir||S41583 yhcV homolog - Methanothermus fervidus 69 3e-11 pir||A75215 MJ0653 homolog PAB2191 - Pyrococcus abyssi (strain O... 69 3e-11 gi|11498453 inosine monophosphate dehydrogenase (guaB-1) [Archae... 68 3e-11 pir||G75056 dehydrogenase PAB0961 - Pyrococcus abyssi (strain Or... 68 6e-11 gb|AAK40465.1| Conserved hypothetical protein [Sulfolobus solfat... 67 8e-11 pir||S75379 MJ1232 protein homolog c04012 - Sulfolobus solfatari... 67 8e-11 pir||E69030 conserved hypothetical protein MJ1225 homolog - Meth... 67 8e-11 >pir||H75197 yhcV homolog PAB2277 - Pyrococcus abyssi (strain Orsay) >gi|5457540|emb|CAB49031.1| (AJ248283) INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE RELATED [Pyrococcus abyssi] Length = 136 Score = 265 bits (671), Expect = 1e-70 Identities = 136/136 (100%), Positives = 136/136 (100%) Query: 1 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR 60 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR Sbjct: 1 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR 60 Query: 61 VIVPGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSD 120 VIVPGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSD Sbjct: 61 VIVPGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSD 120 Query: 121 LLEASRRRLETAISTE 136 LLEASRRRLETAISTE Sbjct: 121 LLEASRRRLETAISTE 136 >pir||A71231 yhcV homolog PH0107 - Pyrococcus horikoshii >gi|3256493|dbj|BAA29176.1| (AP000001) 139aa long hypothetical protein [Pyrococcus horikoshii] Length = 139 Score = 235 bits (594), Expect = 1e-61 Identities = 116/136 (85%), Positives = 129/136 (94%) Query: 1 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR 60 MD+KAPIKVYMTKKL+GVKP T+VQEAS+LMMEFDVGSLVV++D+GNVVGFFTKSDIIRR Sbjct: 4 MDMKAPIKVYMTKKLLGVKPSTSVQEASRLMMEFDVGSLVVINDDGNVVGFFTKSDIIRR 63 Query: 61 VIVPGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSD 120 VIVPGL YDIPV+ IMT+ LIT N NTPLG+VL+KM+EHRIKHILIE+EGKIVGIFTLSD Sbjct: 64 VIVPGLPYDIPVERIMTRNLITANVNTPLGEVLRKMAEHRIKHILIEEEGKIVGIFTLSD 123 Query: 121 LLEASRRRLETAISTE 136 LLEASRRRLETAIS E Sbjct: 124 LLEASRRRLETAISAE 139 >sp|P54606|YHCV_BACSU HYPOTHETICAL 14.9 KD PROTEIN IN CSPB-GLPP INTERGENIC REGION >gi|7429338|pir||B69824 conserved hypothetical protein yhcV - Bacillus subtilis >gi|1239998|emb|CAA65706.1| (X96983) hypothetical protein [Bacillus subtilis] >gi|2633246|emb|CAB12751.1| (Z99108) similar to hypothetical proteins [Bacillus subtilis] Length = 140 Score = 80.8 bits (196), Expect = 6e-15 Identities = 43/115 (37%), Positives = 68/115 (58%), Gaps = 1/115 (0%) Query: 7 IKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGL 66 +K MT ++ V P+ T+QEA+ LM + +VG++ VV+ +G + G T DI R G Sbjct: 4 VKDTMTTQVATVSPNQTIQEAASLMKQHNVGAIPVVE-QGVLKGMLTDRDIALRTTAQGR 62 Query: 67 SYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSDL 121 PV E+M+ EL++ N N L D + M++H+I+ + I D+ +VGI L DL Sbjct: 63 DGQTPVSEVMSTELVSGNPNMSLEDASQLMAQHQIRRLPIVDQNNLVGIVALGDL 117 >sp|P32987|YBP3_ACIAM HYPOTHETICAL 17.7 KD PROTEIN IN BPS2 3'REGION (ORF3) >gi|99249|pir||S22196 MJ0653 homolog - Desulfurolobus ambivalens >gi|40783|emb|CAA45529.1| (X64202) ORF3 [Acidianus ambivalens] Length = 164 Score = 77.6 bits (188), Expect = 5e-14 Identities = 43/114 (37%), Positives = 68/114 (58%), Gaps = 3/114 (2%) Query: 12 TKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYDIP 71 T K+ VKP+ T+ EA+K M E ++GSLVV+D + VVG T+ DI++ D P Sbjct: 10 TTKVYVVKPNVTIAEAAKEMKEHNLGSLVVIDSQNRVVGIITERDIVK--AASNRDIDSP 67 Query: 72 VKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSDLLEA 124 V++ MTK++ V +T + D L M + +H+ +I+ GK+ GI ++ DL A Sbjct: 68 VEKYMTKDVKGVTEDTEVTDALDIMLNNGFRHLPIIKSNGKLYGIVSIRDLARA 121 >gb|AAK43272.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 131 Score = 76.9 bits (186), Expect = 9e-14 Identities = 36/115 (31%), Positives = 74/115 (64%), Gaps = 2/115 (1%) Query: 11 MTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYDI 70 +T+ + VKP+T++++A+K+M ++GSL++VD+ +G T+ DI+ R + ++ D Sbjct: 7 ITRNPLTVKPETSIRDAAKIMKRENLGSLIIVDETNKPIGIVTERDIL-RAVADEVALDS 65 Query: 71 PVKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSDLLEA 124 PV IMT+ LIT+ N + + L M ++ ++H+ ++ G++VG+ ++ D +A Sbjct: 66 PVSTIMTRGLITIPPNKDVTEALIIMYQNNVRHLAVVGQSGELVGVISIRDAAKA 120 >dbj|BAB07461.1| (AP001519) unknown conserved protein in others [Bacillus halodurans] Length = 643 Score = 76.9 bits (186), Expect = 9e-14 Identities = 41/129 (31%), Positives = 71/129 (54%) Query: 7 IKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGL 66 I+ MT+ + V+ VQE ++ MM+ S++V++DE + G T+ D++ RVI G Sbjct: 174 IQDVMTEPAVTVQEQALVQEVARKMMDEGTSSVIVLNDENKLSGIITEKDLVGRVIASGQ 233 Query: 67 SYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSDLLEASR 126 S E+MTK T++ + + + ++IKH+ +E+ G+ +G+ TLSDLL+ Sbjct: 234 SKTQKAYEVMTKNPYTISRHAYYYEAMSMFLMNKIKHLPVEEAGRPLGMVTLSDLLQKKN 293 Query: 127 RRLETAIST 135 R I T Sbjct: 294 RGTLEVIQT 302 >pir||A72481 yhcV homolog APE2489 - Aeropyrum pernix (strain K1) >gi|5106194|dbj|BAA81505.1| (AP000064) 150aa long hypothetical protein [Aeropyrum pernix] Length = 150 Score = 74.9 bits (181), Expect = 3e-13 Identities = 46/123 (37%), Positives = 74/123 (59%), Gaps = 3/123 (2%) Query: 4 KAPIKV--YMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRV 61 K P++ M +++ VKPD V A+KLM+E +GS++VVDDEG + G T+ DI+ V Sbjct: 12 KIPVRASDIMITEVVTVKPDDPVTRAAKLMVENLIGSVLVVDDEGRLRGIVTERDIVYVV 71 Query: 62 IVPGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSD 120 V EIMT+ I V + L V++KMSE ++H+ +++++G VGI + D Sbjct: 72 SEAWDPTKHRVWEIMTENPIVVRPDDDLLTVVRKMSETNVRHLPVVDEKGAPVGIISFRD 131 Query: 121 LLE 123 +L+ Sbjct: 132 VLD 134 >gb|AAK43324.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 156 Score = 74.1 bits (179), Expect = 6e-13 Identities = 40/119 (33%), Positives = 74/119 (61%), Gaps = 3/119 (2%) Query: 7 IKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGL 66 +K YM +++ V +T ++E +++M + +VGS++VVD+ G +G T+ D++R I G Sbjct: 33 VKEYMKTRVITVGRNTMLKEVTRIMTDNNVGSVIVVDN-GKPIGIITERDVVR-AIGKGK 90 Query: 67 SYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSDLLEA 124 S D +EIMT LIT+ ++P+ L M + I+H+ +I+ +G + GI ++ D+ A Sbjct: 91 SLDTIAEEIMTASLITIKEDSPITGALSLMRTYNIRHLPVIDYDGNLRGIISIRDIARA 149 >pir||E72569 yhcV homolog APE1838 - Aeropyrum pernix (strain K1) >gi|5105529|dbj|BAA80842.1| (AP000062) 109aa long hypothetical protein [Aeropyrum pernix] Length = 109 Score = 73.4 bits (177), Expect = 1e-12 Identities = 39/103 (37%), Positives = 59/103 (56%), Gaps = 2/103 (1%) Query: 29 KLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYDIPVKEIMTKELITVNANTP 88 K+M + VVVD + +G FT+ D++R V+ G D PV+E MT+ + V N Sbjct: 2 KMMYTQGKSAAVVVDQDNRPIGIFTERDVVR-VVATGGDLDAPVEEYMTRNPVAVRDNES 60 Query: 89 LGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSDLLEASRRRLE 130 L L M EHR++H+ +++ EGK+VGI T S + E +R E Sbjct: 61 LTKALALMIEHRVRHLPVVDQEGKLVGIITASSITEVLKRYKE 103 >sp|Q58069|Y653_METJA HYPOTHETICAL PROTEIN MJ0653 >gi|2128024|pir||E64381 conserved hypothetical protein MJ0653 - Methanococcus jannaschii >gi|1592300|gb|AAB98648.1| (U67513) inosine-5'-monophosphate dehydrogenase (guaB) [Methanococcus jannaschii] Length = 194 Score = 73.0 bits (176), Expect = 1e-12 Identities = 37/129 (28%), Positives = 76/129 (58%), Gaps = 2/129 (1%) Query: 6 PIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPG 65 P+ M+ ++ + ++ + + +M E ++G++V+V++ +G T+ DI++RV+ Sbjct: 8 PVSEVMSFPVIKATKNMSIYDIANIMTENNIGAVVIVENN-KPIGIVTERDIVKRVVSKN 66 Query: 66 LS-YDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSDLLEA 124 L D+ +E+M+K++IT+ N + + K M+ H IK + + +G++VGI T SD++ Sbjct: 67 LKPKDVLAEEVMSKKIITIPQNASITEAAKIMATHGIKRLPVVKDGELVGIVTQSDIVRV 126 Query: 125 SRRRLETAI 133 S LE I Sbjct: 127 SPELLEIVI 135 >gb|AAK42712.1| Hypothetical protein [Sulfolobus solfataricus] Length = 142 Score = 72.2 bits (174), Expect = 2e-12 Identities = 36/107 (33%), Positives = 73/107 (67%), Gaps = 3/107 (2%) Query: 18 VKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYDIPVKEIMT 77 VK T +A K+M + ++GS+V+V+++ VG FT+ D++R V G + V+ + T Sbjct: 16 VKVGTKAIDACKIMYQNNIGSVVIVNEKDYPVGIFTERDVLRAVAC-GKDLNDKVENLGT 74 Query: 78 -KELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSDLL 122 +L+TV +N+ +G++ +KM ++ I+HI +++DEGK++G+ ++ D++ Sbjct: 75 FGKLVTVKSNSSIGEIAEKMVKNNIRHIVVVDDEGKLIGVVSIKDIV 121 >sp|O58045|IMDH_PYRHO INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP DEHYDROGENASE) (IMPDH) (IMPD) >gi|7427688|pir||E71456 IMP dehydrogenase (EC 1.1.1.205) - Pyrococcus horikoshii >gi|3256697|dbj|BAA29380.1| (AP000001) 486aa long hypothetical inosine-5'-monophosphate dehydrogenase [Pyrococcus horikoshii] Length = 486 Score = 71.4 bits (172), Expect = 4e-12 Identities = 49/127 (38%), Positives = 74/127 (57%), Gaps = 11/127 (8%) Query: 11 MTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYDI 70 + + ++ + PD TV A LM + + L VV+DE VVG TK DI R Sbjct: 99 IVEDVITIAPDETVDFALFLMEKHGIDGLPVVEDE-KVVGIITKKDIAARE-------GK 150 Query: 71 PVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDE-GKIVGIFTLSDLLEASRRRL 129 VKE+MTKE+ITV + + + LK M E+RI + + DE GK+VG+ T+SDL+ +R++ Sbjct: 151 LVKELMTKEVITVPESIEVEEALKIMIENRIDRLPVVDERGKLVGLITMSDLV--ARKKY 208 Query: 130 ETAISTE 136 + A+ E Sbjct: 209 KNAVRDE 215 >pir||G69030 MJ0653 homolog MTH1226 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622337|gb|AAB85715.1| (AE000890) inosine-5'-monophosphate dehydrogenase related protein V [Methanobacterium thermoautotrophicum] Length = 187 Score = 71.0 bits (171), Expect = 5e-12 Identities = 39/123 (31%), Positives = 71/123 (57%), Gaps = 2/123 (1%) Query: 1 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR 60 M+ K + MT ++ P +V EA+ +M E VGS ++V G T+SDIIR+ Sbjct: 3 METKVTVHDAMTSNVITADPGISVAEAASIMTEKKVGS-IIVKSNSEPEGLITESDIIRK 61 Query: 61 VIVPGL-SYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLS 119 V+ L + ++ V E+MT+ LI++ + L + + M+++ I+ + + +G +VGI T S Sbjct: 62 VVSRDLRASEVTVGEVMTRNLISIEPDRELSEAARLMAKNSIRRLPVVRDGALVGILTSS 121 Query: 120 DLL 122 D++ Sbjct: 122 DVM 124 >pir||D71451 MJ0653 homolog PH0267 - Pyrococcus horikoshii >gi|3256656|dbj|BAA29339.1| (AP000001) 178aa long hypothetical protein [Pyrococcus horikoshii] Length = 178 Score = 71.0 bits (171), Expect = 5e-12 Identities = 41/125 (32%), Positives = 74/125 (58%), Gaps = 2/125 (1%) Query: 1 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR 60 M K ++ + +K + VKP +V + +K++ + VGS VV+D +G V+G T+ DI+ + Sbjct: 1 MAPKILVEQIVKRKAVVVKPTDSVHKVAKVLSKNKVGSAVVMD-KGEVLGVVTERDILDK 59 Query: 61 VIVPGLS-YDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLS 119 V+ G ++ V+EIMTK + + + + D ++ M+E ++ IL+ GK +G T + Sbjct: 60 VVAKGKDPKEVKVEEIMTKNPVKIEYDYDVQDAIELMTEKGVRRILVTKFGKPIGFVTAT 119 Query: 120 DLLEA 124 DLL A Sbjct: 120 DLLAA 124 >pir||H72290 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981687|gb|AAD36216.1|AE001771_9 (AE001771) conserved hypothetical protein [Thermotoga maritima] Length = 215 Score = 71.0 bits (171), Expect = 5e-12 Identities = 40/128 (31%), Positives = 74/128 (57%), Gaps = 12/128 (9%) Query: 7 IKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGL 66 +K +MT+ + + P+T+ EA KLM + + L+V+ +E +VG T+ D++ Sbjct: 3 VKDFMTRNPITIAPETSFSEALKLMKQNKIKRLIVMKNE-KIVGIVTEKDLLYASPSKAT 61 Query: 67 SYDI----------PVKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGI 115 + +I ++EIMTK+++TVN NTP+ D + M E I + +++D G++VGI Sbjct: 62 TLNIWELHYLLSKLKIEEIMTKDVVTVNENTPIEDAARIMEEKDISGLPVVDDAGRLVGI 121 Query: 116 FTLSDLLE 123 T +D+ + Sbjct: 122 ITQTDIFK 129 >sp|P42851|IMDH_PYRFU INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP DEHYDROGENASE) (IMPDH) (IMPD) >gi|2117506|pir||JC4998 IMP dehydrogenase (EC 1.1.1.205) - Pyrococcus furiosus >gi|595287|gb|AAC44532.1| (U08814) IMP dehydrogenase [Pyrococcus furiosus] Length = 485 Score = 70.2 bits (169), Expect = 9e-12 Identities = 43/128 (33%), Positives = 76/128 (58%), Gaps = 11/128 (8%) Query: 10 YMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYD 69 ++ + ++ + PD T+ A LM + + L VV+++ VVG TK DI R Sbjct: 98 FIVEDVITIAPDETIDYALFLMEKHGIDGLPVVEED-RVVGIITKKDIAARE-------G 149 Query: 70 IPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSDLLEASRRR 128 VKE+MT+E+ITV + + + LK M E+RI + ++ ++GK+VG+ T+SDL+ +R++ Sbjct: 150 RTVKELMTREVITVPESVDVEEALKIMMENRIDRLPVVNEDGKLVGLITMSDLV--ARKK 207 Query: 129 LETAISTE 136 + A+ E Sbjct: 208 YKNAVRNE 215 >sp|Q57892|Y450_METJA HYPOTHETICAL PROTEIN MJ0450 >gi|2128329|pir||B64356 hypothetical protein MJ0450 - Methanococcus jannaschii >gi|1591154|gb|AAB98439.1| (U67496) inosine monophosphate dehydrogenase isolog [Methanococcus jannaschii] Length = 186 Score = 70.2 bits (169), Expect = 9e-12 Identities = 41/129 (31%), Positives = 78/129 (59%), Gaps = 4/129 (3%) Query: 6 PIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGN--VVGFFTKSDIIRRVIV 63 P+ + M K ++ V D +V + +KLM+E DV ++VV + N + T DII++V++ Sbjct: 6 PVLLIMKKPIV-VSGDVSVYDVAKLMVEQDVPCVLVVCERPNHESIEVATDKDIIKKVLI 64 Query: 64 PGLSYD-IPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLSDLL 122 L D + V++I + +L+T+ NT + + L+ M++++ + I D+GKIVG+ T DL+ Sbjct: 65 RKLPPDKVKVEDISSGKLVTIPPNTTIDEALEIMNKYKTNELFIVDDGKIVGVITEEDLI 124 Query: 123 EASRRRLET 131 + + + T Sbjct: 125 KIAPEIIST 133 >pir||E75015 IMP dehydrogenase (EC 1.1.1.205) PAB1250 - Pyrococcus abyssi (strain Orsay) >gi|5459077|emb|CAB50563.1| (AJ248288) INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (EC 1.1.1.205) (IMP DEHYDROGENASE) (IMPDH) (IMPD). [Pyrococcus abyssi] Length = 485 Score = 70.2 bits (169), Expect = 9e-12 Identities = 44/128 (34%), Positives = 77/128 (59%), Gaps = 11/128 (8%) Query: 10 YMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYD 69 ++ + ++ + P+ TV A LM + D+ L VV++E VVG +K DI R Sbjct: 98 FIVEDVITISPEETVDFALFLMEKHDIDGLPVVENE-KVVGIISKKDIAARE-------G 149 Query: 70 IPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTLSDLLEASRRR 128 VKE+MTK++ITV N + + LK M E+RI + +++ EG+++G+ T+SDL+ +R++ Sbjct: 150 KLVKELMTKDVITVPENIEVEEALKIMIENRIDRLPVVDKEGRLIGLITMSDLV--ARKK 207 Query: 129 LETAISTE 136 + A+ E Sbjct: 208 YKNAVRDE 215 >pir||F72730 yhcV homolog APE0383 - Aeropyrum pernix (strain K1) >gi|5104022|dbj|BAA79338.1| (AP000059) 147aa long hypothetical protein [Aeropyrum pernix] Length = 147 Score = 69.9 bits (168), Expect = 1e-11 Identities = 41/107 (38%), Positives = 65/107 (60%), Gaps = 3/107 (2%) Query: 20 PDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGLSYD-IPVKEIMTK 78 P T+V+EA+K+M+E VGSL+VV++ ++G TK+DIIR V+ GL + + V +IMT+ Sbjct: 14 PMTSVKEAAKIMLENRVGSLIVVNERNTLLGILTKTDIIREVVAKGLDPESVRVGDIMTR 73 Query: 79 ELITVNANTPLGDVLKKMSEHRIKH--ILIEDEGKIVGIFTLSDLLE 123 V + + M EH I H +L + K VGI T +D+++ Sbjct: 74 NPYYVYTDDSVERAASLMGEHNIGHLPVLDPETEKPVGIVTKTDIVK 120 >pir||S41583 yhcV homolog - Methanothermus fervidus Length = 135 Score = 68.7 bits (165), Expect = 3e-11 Identities = 42/129 (32%), Positives = 72/129 (55%), Gaps = 6/129 (4%) Query: 7 IKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIVPGL 66 +K MTK ++ V P+ V A + +M+ + +L VV +G ++G T +D+ +I+ Sbjct: 7 VKDVMTKNVITVDPEEDVVFAFEKLMKNKISALPVVK-KGKLLGIVTATDLGHNLILDKY 65 Query: 67 SYDIPVKEIMTKELITVNANTPLGDVLKKMSEHR-----IKHILIEDEGKIVGIFTLSDL 121 VKEIM K+++ V+ N L DV+KKM EH I +++++ +I GI + D+ Sbjct: 66 KLGTKVKEIMVKDVVCVSPNDTLADVVKKMYEHGDKDEIINQLVVKENDEIKGIISDGDI 125 Query: 122 LEASRRRLE 130 + A R LE Sbjct: 126 IRALRSTLE 134 >pir||A75215 MJ0653 homolog PAB2191 - Pyrococcus abyssi (strain Orsay) >gi|5457677|emb|CAB49168.1| (AJ248283) INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE related [Pyrococcus abyssi] Length = 179 Score = 68.7 bits (165), Expect = 3e-11 Identities = 39/125 (31%), Positives = 71/125 (56%), Gaps = 2/125 (1%) Query: 1 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR 60 M K ++ + +K + VKP +V ++++ + VGS VV+D + V+G T+ DI+ + Sbjct: 1 MATKILVEQVVKRKAVVVKPSDSVHRVARILSKNKVGSAVVMDKD-EVLGIVTERDILDK 59 Query: 61 VIVPGLS-YDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDEGKIVGIFTLS 119 V+ G ++ V+EIMTK + + + + D + M+E ++ IL+ GK +G T + Sbjct: 60 VVAKGKDPKEVKVEEIMTKNPVKIEYDYDVQDAIDLMTEKGVRRILVTKFGKPIGFVTAA 119 Query: 120 DLLEA 124 DLL A Sbjct: 120 DLLSA 124 >gi|11498453 inosine monophosphate dehydrogenase (guaB-1) [Archaeoglobus fulgidus] >gi|7429344|pir||G69355 MJ0653 homolog AF0847 - Archaeoglobus fulgidus >gi|2649754|gb|AAB90390.1| (AE001045) inosine monophosphate dehydrogenase (guaB-1) [Archaeoglobus fulgidus] Length = 189 Score = 68.3 bits (164), Expect = 3e-11 Identities = 39/127 (30%), Positives = 73/127 (56%), Gaps = 3/127 (2%) Query: 1 MDVKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRR 60 M P+K MT + VK +V +K ++E+ VGS VVV+D G VG T+ D+I + Sbjct: 1 MQTDLPVKEVMTTVVCTVKRTDSVHNLAKKLVEYGVGSAVVVED-GRPVGIVTEKDLISK 59 Query: 61 VIVPG-LSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHI-LIEDEGKIVGIFTL 118 ++ + + V+E+M++ +IT+ NT L + + M + I+ + ++ + +++GI T Sbjct: 60 IVARNKVPSKVLVEEVMSQPVITIGPNTSLREAARIMMKRGIRRLPVVNNNQELIGIITD 119 Query: 119 SDLLEAS 125 +D+L S Sbjct: 120 NDILSVS 126 >pir||G75056 dehydrogenase PAB0961 - Pyrococcus abyssi (strain Orsay) >gi|5458861|emb|CAB50348.1| (AJ248287) dehydrogenase [Pyrococcus abyssi] Length = 392 Score = 67.5 bits (162), Expect = 6e-11 Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 14/141 (9%) Query: 4 KAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIV 63 K ++ +MTK ++ + PD TV +A M + + + VVD+EG + G T D+I R I Sbjct: 129 KRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIK 188 Query: 64 PGLS-------------YDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIEDE- 109 P + + ++E M K +IT+ + + + M ++ I +++ DE Sbjct: 189 PRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDEN 248 Query: 110 GKIVGIFTLSDLLEASRRRLE 130 K+VGI T+ DLL R +E Sbjct: 249 NKVVGILTVKDLLLPISRMVE 269 >gb|AAK40465.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 300 Score = 67.1 bits (161), Expect = 8e-11 Identities = 38/122 (31%), Positives = 69/122 (56%), Gaps = 3/122 (2%) Query: 4 KAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIV 63 K +K ++KKL+ +KP+T+++EAS + + + V++ + VVG T +DII+ Sbjct: 171 KEKVKNLISKKLIALKPETSLREASMIFYKEAIRGAPVINQDEKVVGILTTADIIKAFFE 230 Query: 64 PGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIED-EGKIVGIFTLSDLL 122 +Y V + M +I++N N L D ++KM + + +L+ D K VGI T +D+L Sbjct: 231 G--NYTAKVSDYMKTNVISINENEDLLDAIRKMIIYNVGRLLVLDSNNKAVGIVTRTDIL 288 Query: 123 EA 124 + Sbjct: 289 RS 290 >pir||S75379 MJ1232 protein homolog c04012 - Sulfolobus solfataricus >gi|1707784|emb|CAA69582.1| (Y08257) orf c04012 [Sulfolobus solfataricus] Length = 300 Score = 67.1 bits (161), Expect = 8e-11 Identities = 38/122 (31%), Positives = 69/122 (56%), Gaps = 3/122 (2%) Query: 4 KAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVIV 63 K +K ++KKL+ +KP+T+++EAS + + + V++ + VVG T +DII+ Sbjct: 171 KEKVKNLISKKLIALKPETSLREASMIFYKEAIRGAPVINQDEKVVGILTTADIIKAFFE 230 Query: 64 PGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILIED-EGKIVGIFTLSDLL 122 +Y V + M +I++N N L D ++KM + + +L+ D K VGI T +D+L Sbjct: 231 G--NYTAKVSDYMKTNVISINENEDLLDAIRKMIIYNVGRLLVLDSNNKAVGIVTRTDIL 288 Query: 123 EA 124 + Sbjct: 289 RS 290 >pir||E69030 conserved hypothetical protein MJ1225 homolog - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622335|gb|AAB85713.1| (AE000890) inosine-5'-monophosphate dehydrogenase related protein III [Methanobacterium thermoautotrophicum] Length = 313 Score = 67.1 bits (161), Expect = 8e-11 Identities = 38/130 (29%), Positives = 71/130 (54%), Gaps = 11/130 (8%) Query: 3 VKAPIKVYMTKKLMGVKPDTTVQEASKLMMEFDVGSLVVVDDEGNVVGFFTKSDIIRRVI 62 V P+K MT+ ++ + ++ +A +M+E VG+L VVDD+ + G ++ D + ++ Sbjct: 107 VNEPVKSIMTRDVISITTRDSIADAVSMMLENSVGALPVVDDDEKIAGIVSERDFV--LL 164 Query: 63 VPGLSYDIPVKEIMTKELITVNANTPLGDVLKKMSEHRIKHILI---------EDEGKIV 113 + G+ D +E MT ++I+ TP+ K M +R++ I + +E K+V Sbjct: 165 MAGVFNDEVTEEHMTADVISTTPGTPIEGASKIMVRNRLRRIPVLGEERKTPHPEEEKLV 224 Query: 114 GIFTLSDLLE 123 GI T +D+LE Sbjct: 225 GIVTSTDILE 234 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.318 0.137 0.367 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 44133125 Number of Sequences: 2977 Number of extensions: 1673832 Number of successful extensions: 6283 Number of sequences better than 1.0e-10: 26 Number of HSP's better than 0.0 without gapping: 3 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 6202 Number of HSP's gapped (non-prelim): 54 length of query: 136 length of database: 189,106,746 effective HSP length: 57 effective length of query: 79 effective length of database: 154,992,987 effective search space: 12244445973 effective search space used: 12244445973 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 160 (66.7 bits)