BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2278 (icc) DE:lacZ expression regulatory protein (icc) (505 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||G75197 lacz expression regulatory protein (icc) PAB2278 - P... 1037 0.0 pir||F71230 hypothetical protein PH0104 - Pyrococcus horikoshii ... 969 0.0 pir||C69097 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.... 170 3e-41 pir||A70360 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.... 150 4e-35 gi|11500006 lacZ expression regulatory protein (icc) [Archaeoglo... 146 5e-34 pir||F69104 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.... 140 3e-32 sp|P36650|ICC_ECOLI ICC PROTEIN >gi|7428142|pir||F65090 3',5'-cy... 74 3e-12 gb|AAA69200.1| (U28377) icc gene product [Escherichia coli] 69 9e-11 pir||T35867 hypothetical protein SC9B1.22c - Streptomyces coelic... 69 9e-11 >pir||G75197 lacz expression regulatory protein (icc) PAB2278 - Pyrococcus abyssi (strain Orsay) >gi|5457539|emb|CAB49030.1| (AJ248283) lacZ expression regulatory protein (icc) [Pyrococcus abyssi] Length = 505 Score = 1037 bits (2651), Expect = 0.0 Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 1 MMKMLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASY 60 MMKMLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASY Sbjct: 1 MMKMLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASY 60 Query: 61 LLKKIEKPLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRVG 120 LLKKIEKPLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRVG Sbjct: 61 LLKKIEKPLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRVG 120 Query: 121 GYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLYM 180 GYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLYM Sbjct: 121 GYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLYM 180 Query: 181 CGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITKDKVKVVIRRLTGDEEEK 240 CGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITKDKVKVVIRRLTGDEEEK Sbjct: 181 CGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITKDKVKVVIRRLTGDEEEK 240 Query: 241 EHKPIRPKIFIPRGRRLLRIVHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGD 300 EHKPIRPKIFIPRGRRLLRIVHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGD Sbjct: 241 EHKPIRPKIFIPRGRRLLRIVHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGD 300 Query: 301 VVEKGIERYFEMALEYYEKVKAEKIIVPGHNDISYLGYELFKEYFGEPEIVERGDFVFIP 360 VVEKGIERYFEMALEYYEKVKAEKIIVPGHNDISYLGYELFKEYFGEPEIVERGDFVFIP Sbjct: 301 VVEKGIERYFEMALEYYEKVKAEKIIVPGHNDISYLGYELFKEYFGEPEIVERGDFVFIP 360 Query: 361 ILSAQYETQIGVVGRTGQKMLSRLLDDFEEKFRIIVMHHNLVPVPGVREIGYLEDAGNVL 420 ILSAQYETQIGVVGRTGQKMLSRLLDDFEEKFRIIVMHHNLVPVPGVREIGYLEDAGNVL Sbjct: 361 ILSAQYETQIGVVGRTGQKMLSRLLDDFEEKFRIIVMHHNLVPVPGVREIGYLEDAGNVL 420 Query: 421 KIITDKKTELTLTGHGGNSNAVKVEKSPIINAGSISWELHRNPFGNSFNVIDIYEDMIVA 480 KIITDKKTELTLTGHGGNSNAVKVEKSPIINAGSISWELHRNPFGNSFNVIDIYEDMIVA Sbjct: 421 KIITDKKTELTLTGHGGNSNAVKVEKSPIINAGSISWELHRNPFGNSFNVIDIYEDMIVA 480 Query: 481 FEIQATWGSRKLLGMWKIKSEIPWL 505 FEIQATWGSRKLLGMWKIKSEIPWL Sbjct: 481 FEIQATWGSRKLLGMWKIKSEIPWL 505 >pir||F71230 hypothetical protein PH0104 - Pyrococcus horikoshii >gi|3256490|dbj|BAA29173.1| (AP000001) 505aa long hypothetical protein [Pyrococcus horikoshii] Length = 505 Score = 969 bits (2478), Expect = 0.0 Identities = 459/505 (90%), Positives = 487/505 (95%) Query: 1 MMKMLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASY 60 MM MLIAHISDTHITNEVAFKSYAYDLI NEINT+PFDLV+HTGDVTNNGLREEYEHASY Sbjct: 1 MMDMLIAHISDTHITNEVAFKSYAYDLIVNEINTKPFDLVVHTGDVTNNGLREEYEHASY 60 Query: 61 LLKKIEKPLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRVG 120 L+KKIEKPL+V PGNHDARNVGYELFEKYIGPL GVYEF +GVIIWLDSTIPDLSDGRVG Sbjct: 61 LIKKIEKPLVVVPGNHDARNVGYELFEKYIGPLYGVYEFDNGVIIWLDSTIPDLSDGRVG 120 Query: 121 GYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLYM 180 GYKFKWLK KLE YSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLL+H+VTLYM Sbjct: 121 GYKFKWLKEKLEAYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLTHEVTLYM 180 Query: 181 CGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITKDKVKVVIRRLTGDEEEK 240 CGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKIT VKVVIRRLTGDEE K Sbjct: 181 CGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITDKGVKVVIRRLTGDEESK 240 Query: 241 EHKPIRPKIFIPRGRRLLRIVHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGD 300 EH PIRPKIFIPRGRRLLRIV +SESNVSDRVYFRKRTLENAI+AINEKYKPDIV+HCGD Sbjct: 241 EHNPIRPKIFIPRGRRLLRIVQISESNVSDRVYFRKRTLENAIKAINEKYKPDIVIHCGD 300 Query: 301 VVEKGIERYFEMALEYYEKVKAEKIIVPGHNDISYLGYELFKEYFGEPEIVERGDFVFIP 360 VVEKGIERY+E A+EYYEKVK EKIIVPGHNDISYLGYELF+EYFGEPE++E GDFVFIP Sbjct: 301 VVEKGIERYYEKAMEYYEKVKGEKIIVPGHNDISYLGYELFREYFGEPEVLELGDFVFIP 360 Query: 361 ILSAQYETQIGVVGRTGQKMLSRLLDDFEEKFRIIVMHHNLVPVPGVREIGYLEDAGNVL 420 ILSAQYETQIGVVGRTGQKMLSR+L++F EKFRI++MHHNLVPVPGV+EIGYLEDAGNVL Sbjct: 361 ILSAQYETQIGVVGRTGQKMLSRMLEEFREKFRIVIMHHNLVPVPGVKEIGYLEDAGNVL 420 Query: 421 KIITDKKTELTLTGHGGNSNAVKVEKSPIINAGSISWELHRNPFGNSFNVIDIYEDMIVA 480 KIIT+ +TELTLTGHGGN++AVKVEKSPIINAGSISWELHRNPFGNSFN+IDIYEDM+VA Sbjct: 421 KIITENETELTLTGHGGNTSAVKVEKSPIINAGSISWELHRNPFGNSFNIIDIYEDMVVA 480 Query: 481 FEIQATWGSRKLLGMWKIKSEIPWL 505 FEIQATWGSRK+LGMWKIKSEIPWL Sbjct: 481 FEIQATWGSRKVLGMWKIKSEIPWL 505 >pir||C69097 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA homolog - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622852|gb|AAB86192.1| (AE000928) transcriptional regulator Icc related protein [Methanobacterium thermoautotrophicum] Length = 262 Score = 170 bits (427), Expect = 3e-41 Identities = 92/229 (40%), Positives = 134/229 (58%), Gaps = 3/229 (1%) Query: 2 MKMLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASYL 61 M+ IA ISD H E F + +++ DL+I +GD+T G EYE A+ Sbjct: 1 MEKKIAQISDVHF-GEKNFSDQLRKNLLHQLENENPDLIIVSGDLTTEGYSHEYELAAAF 59 Query: 62 LKKIEK--PLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRV 119 + ++ PGNHDARNVG FEK IG V+ + +I LDS+ PD++DG++ Sbjct: 60 VDELRTITSTYTIPGNHDARNVGLIHFEKLIGRRKFVHHDSEFAVIGLDSSEPDINDGQI 119 Query: 120 GGYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLY 179 G + WL+ +LE KIV HHHL+P+P+TGRERN+L ++GD+L LL + V Sbjct: 120 GMDQLDWLRKELERVPDHLCKIVTFHHHLLPIPNTGRERNILLDSGDLLKLLKEYGVDFV 179 Query: 180 MCGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITKDKVKV 228 + GHKHVPNV+ +E +V N+G A+ RK R S+N ++I D++ V Sbjct: 180 LNGHKHVPNVWMIEGMVTLNSGTATTRKLRGETFPSHNQLRINDDRISV 228 Score = 84.3 bits (205), Expect = 3e-15 Identities = 61/246 (24%), Positives = 115/246 (45%), Gaps = 12/246 (4%) Query: 261 VHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGDVVEKGIERYFEMALEYYEKV 320 VH E N SD++ RK L E PD+++ GD+ +G +E+A + +++ Sbjct: 11 VHFGEKNFSDQL--RKNLLHQL-----ENENPDLIIVSGDLTTEGYSHEYELAAAFVDEL 63 Query: 321 KA--EKIIVPGHNDISYLGYELFKEYFGEPEIVER-GDFVFIPILSAQYETQIGVVGRTG 377 + +PG++D +G F++ G + V +F I + S++ + G +G Sbjct: 64 RTITSTYTIPGNHDARNVGLIHFEKLIGRRKFVHHDSEFAVIGLDSSEPDINDGQIGMDQ 123 Query: 378 QKMLSRLLDDFEEKF-RIIVMHHNLVPVPGV-REIGYLEDAGNVLKIITDKKTELTLTGH 435 L + L+ + +I+ HH+L+P+P RE L D+G++LK++ + + L GH Sbjct: 124 LDWLRKELERVPDHLCKIVTFHHHLLPIPNTGRERNILLDSGDLLKLLKEYGVDFVLNGH 183 Query: 436 GGNSNAVKVEKSPIINAGSISWELHRNPFGNSFNVIDIYEDMIVAFEIQATWGSRKLLGM 495 N +E +N+G+ + R S N + I +D I I GS + + Sbjct: 184 KHVPNVWMIEGMVTLNSGTATTRKLRGETFPSHNQLRINDDRISVDLINTENGSVREIAS 243 Query: 496 WKIKSE 501 + ++ E Sbjct: 244 YSVRVE 249 >pir||A70360 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA homolog - Aquifex aeolicus >gi|2983283|gb|AAC06876.1| (AE000702) putative protein [Aquifex aeolicus] Length = 249 Score = 150 bits (375), Expect = 4e-35 Identities = 85/223 (38%), Positives = 135/223 (60%), Gaps = 3/223 (1%) Query: 4 MLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASYLLK 63 M IAHISD H+ E +L+ +N + DL+I TGD+T+ G EY+ A L+ Sbjct: 1 MKIAHISDLHVKCEWYEDRLGNNLV-KYLNAQKPDLLIITGDLTDYGYYAEYKRAYSFLE 59 Query: 64 KIE-KPLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRVGGY 122 IE + +V PGNHDARN GYELFE++ G + YE + VII +DS++PD +G +G Sbjct: 60 LIEVEKRVVVPGNHDARNEGYELFEEFFGTRMPYYEDEYMVIIGMDSSLPDREEGHIGRK 119 Query: 123 KFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLYMCG 182 +K+L+ L++ K+KIVA HHH+VP+P TG + +L +AG+++ ++ V L + G Sbjct: 120 GYKFLRETLKD-KGDKLKIVALHHHVVPIPATGSDLAILTDAGNLMKVVDELGVELVLTG 178 Query: 183 HKHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITKDK 225 HKH V+++ + AG A+ R+ + D S+ ++ + +K Sbjct: 179 HKHKAWVWKLNETYYVTAGTATTRRLKAKDYPSFYMLYLEDEK 221 Score = 113 bits (279), Expect = 6e-24 Identities = 62/200 (31%), Positives = 116/200 (58%), Gaps = 5/200 (2%) Query: 258 LRIVHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGDVVEKGIERYFEMALEYY 317 ++I H+S+ +V ++ R N ++ +N + KPD+++ GD+ + G ++ A + Sbjct: 1 MKIAHISDLHVKCE-WYEDRLGNNLVKYLNAQ-KPDLLIITGDLTDYGYYAEYKRAYSFL 58 Query: 318 EKVKAEK-IIVPGHNDISYLGYELFKEYFGEPEIVERGDF-VFIPILSAQYETQIGVVGR 375 E ++ EK ++VPG++D GYELF+E+FG ++ V I + S+ + + G +GR Sbjct: 59 ELIEVEKRVVVPGNHDARNEGYELFEEFFGTRMPYYEDEYMVIIGMDSSLPDREEGHIGR 118 Query: 376 TGQKMLSRLLDDFEEKFRIIVMHHNLVPVPGV-REIGYLEDAGNVLKIITDKKTELTLTG 434 G K L L D +K +I+ +HH++VP+P ++ L DAGN++K++ + EL LTG Sbjct: 119 KGYKFLRETLKDKGDKLKIVALHHHVVPIPATGSDLAILTDAGNLMKVVDELGVELVLTG 178 Query: 435 HGGNSNAVKVEKSPIINAGS 454 H + K+ ++ + AG+ Sbjct: 179 HKHKAWVWKLNETYYVTAGT 198 >gi|11500006 lacZ expression regulatory protein (icc) [Archaeoglobus fulgidus] >gi|7428147|pir||G69553 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA homolog - Archaeoglobus fulgidus >gi|2650659|gb|AAB91233.1| (AE001107) lacZ expression regulatory protein (icc) [Archaeoglobus fulgidus] Length = 372 Score = 146 bits (365), Expect = 5e-34 Identities = 82/245 (33%), Positives = 134/245 (54%), Gaps = 5/245 (2%) Query: 4 MLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASYLLK 63 M I HISD H E+ + + +IN DL++ TGD++ G+ E A L Sbjct: 1 MRIVHISDLHFGEELIREKV--EKAVRQINEIEPDLLVITGDLSCWGIHSEMRDAYETLL 58 Query: 64 KIEKPLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRVGGYK 123 ++ I PGNHDARN+GYE F+ Y G ++ +I DST PDL DG +G + Sbjct: 59 DLKPDYIAVPGNHDARNIGYEFFQLYFGETKKYWKNDVVSLIAADSTQPDLDDGYIGKEQ 118 Query: 124 FKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLYMCGH 183 W+ +K+ + + I+A HHH+ P+P TGRERNVL +AG++++LL+++ ++ + GH Sbjct: 119 RDWIVSKIRK---DRFNILALHHHIAPIPKTGRERNVLIDAGEMVELLIANGISAVLAGH 175 Query: 184 KHVPNVYRVEDLVVDNAGCASCRKTRKGDVNSYNIVKITKDKVKVVIRRLTGDEEEKEHK 243 +H+P R+ V +AG K ++YN+++I + + + +R + E E Sbjct: 176 RHMPYSLRLMRTHVIHAGTLGSFKVLGMPDHNYNVIEIKDNTLTLKLRFVDYGEVEIGRY 235 Query: 244 PIRPK 248 I P+ Sbjct: 236 TINPE 240 Score = 99.5 bits (244), Expect = 8e-20 Identities = 73/250 (29%), Positives = 136/250 (54%), Gaps = 12/250 (4%) Query: 258 LRIVHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGDVVEKGIERYFEMALEYY 317 +RIVH+S+ + + + K +E A+R INE +PD++V GD+ GI A E Sbjct: 1 MRIVHISDLHFGEELIREK--VEKAVRQINE-IEPDLLVITGDLSCWGIHSEMRDAYETL 57 Query: 318 EKVKAEKIIVPGHNDISYLGYELFKEYFGEPEIVERGDFV-FIPILSAQYETQIGVVGRT 376 +K + I VPG++D +GYE F+ YFGE + + D V I S Q + G +G+ Sbjct: 58 LDLKPDYIAVPGNHDARNIGYEFFQLYFGETKKYWKNDVVSLIAADSTQPDLDDGYIGKE 117 Query: 377 GQK-MLSRLLDDFEEKFRIIVMHHNLVPVPGV-REIGYLEDAGNVLKIITDKKTELTLTG 434 + ++S++ D +F I+ +HH++ P+P RE L DAG +++++ L G Sbjct: 118 QRDWIVSKIRKD---RFNILALHHHIAPIPKTGRERNVLIDAGEMVELLIANGISAVLAG 174 Query: 435 HGGNSNAVKVEKSPIINAGSI-SWELHRNPFGNSFNVIDIYEDMIVAFEIQATWGSRKLL 493 H ++++ ++ +I+AG++ S+++ P +++NVI+I +D + +++ + Sbjct: 175 HRHMPYSLRLMRTHVIHAGTLGSFKVLGMP-DHNYNVIEI-KDNTLTLKLRFVDYGEVEI 232 Query: 494 GMWKIKSEIP 503 G + I E P Sbjct: 233 GRYTINPETP 242 >pir||F69104 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA homolog MTH178 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621221|gb|AAB84684.1| (AE000805) Icc related protein [Methanobacterium thermoautotrophicum] Length = 196 Score = 140 bits (350), Expect = 3e-32 Identities = 77/185 (41%), Positives = 109/185 (58%), Gaps = 2/185 (1%) Query: 4 MLIAHISDTHITNEVAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREEYEHASYLLK 63 +LIAHISD H+ FK +IN D + TGD+T+NG E+ A+ L Sbjct: 2 VLIAHISDLHV-GAPNFKEDILLEAIRQINKLKPDATVITGDLTDNGYYLEFLQAAEYLS 60 Query: 64 KIEKPLIVAPGNHDARNVGYELFEKYIGPLIGVYEFKDGVIIWLDSTIPDLSDGRVGGYK 123 ++ P I PGNHDAR+VG E FE G + II LDS+ PDL G++G + Sbjct: 61 DLKGPHIFVPGNHDARHVGNETFEDVFRYRRGTFVMDGLTIIGLDSSEPDLDYGKIGRSQ 120 Query: 124 FKWLKAKLEEYSHK-KIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLSHDVTLYMCG 182 W++ +L+ S + I+++A HHH++P+P TGRERNVL +AGD+L ++S L + G Sbjct: 121 QIWMEDELDRASSRGHIRVIALHHHIIPVPKTGRERNVLADAGDILQSIISKGADLVISG 180 Query: 183 HKHVP 187 HKHVP Sbjct: 181 HKHVP 185 Score = 95.2 bits (233), Expect = 2e-18 Identities = 64/187 (34%), Positives = 99/187 (52%), Gaps = 14/187 (7%) Query: 257 LLRIVHVSESNVSDRVYFRKRTLENAIRAINEKYKPDIVVHCGDVVEKGIERYFEMALEY 316 ++ I H+S+ +V F++ L AIR IN K KPD V GD+ + G F A EY Sbjct: 1 MVLIAHISDLHVG-APNFKEDILLEAIRQIN-KLKPDATVITGDLTDNGYYLEFLQAAEY 58 Query: 317 YEKVKAEKIIVPGHNDISYLGYELFKEYFGEPEIVERGDFV-----FIPILSAQYETQIG 371 +K I VPG++D ++G E F++ F RG FV I + S++ + G Sbjct: 59 LSDLKGPHIFVPGNHDARHVGNETFEDVFR----YRRGTFVMDGLTIIGLDSSEPDLDYG 114 Query: 372 VVGRTGQKMLSRLLDDFEEK--FRIIVMHHNLVPVPGV-REIGYLEDAGNVLKIITDKKT 428 +GR+ Q + LD + R+I +HH+++PVP RE L DAG++L+ I K Sbjct: 115 KIGRSQQIWMEDELDRASSRGHIRVIALHHHIIPVPKTGRERNVLADAGDILQSIISKGA 174 Query: 429 ELTLTGH 435 +L ++GH Sbjct: 175 DLVISGH 181 >sp|P36650|ICC_ECOLI ICC PROTEIN >gi|7428142|pir||F65090 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA - Escherichia coli (strain K-12) >gi|453396|dbj|BAA03989.1| (D16557) Icc [Escherichia coli] >gi|1789410|gb|AAC76068.1| (AE000385) regulator of lacZ [Escherichia coli K12] Length = 275 Score = 74.1 bits (179), Expect = 3e-12 Identities = 53/194 (27%), Positives = 96/194 (49%), Gaps = 13/194 (6%) Query: 3 KMLIAHISDTHITNEV--------AFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREE 54 ++ I I+DTH+ + ++SY L A + FDL++ TGD+ + Sbjct: 14 RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73 Query: 55 YEHASYLLKKIEKPLIVAPGNHDARNVGYE-LFEKYIGPLIGVYEFKDGVIIWLDSTIPD 113 Y+H + + P + PGNHD + Y L + I P V+ + I+ LDS + Sbjct: 74 YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133 Query: 114 LSDGRVGGYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLS 173 + G + ++ +WL+ KL + + ++ ++ HHH +P + +++ L NAG+ LD +L+ Sbjct: 134 VPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGE-LDTVLA 191 Query: 174 H--DVTLYMCGHKH 185 V +CGH H Sbjct: 192 KFPHVKYLLCGHIH 205 >gb|AAA69200.1| (U28377) icc gene product [Escherichia coli] Length = 231 Score = 69.5 bits (167), Expect = 9e-11 Identities = 44/152 (28%), Positives = 79/152 (51%), Gaps = 5/152 (3%) Query: 37 FDLVIHTGDVTNNGLREEYEHASYLLKKIEKPLIVAPGNHDARNVGYE-LFEKYIGPLIG 95 FDL++ TGD+ + Y+H + + P + PGNHD + Y L + I P Sbjct: 12 FDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKR 71 Query: 96 VYEFKDGVIIWLDSTIPDLSDGRVGGYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTG 155 V+ + I+ LDS + + G + ++ +WL+ KL + + ++ ++ HHH +P + Sbjct: 72 VFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSW 130 Query: 156 RERNVLFNAGDVLDLLLSH--DVTLYMCGHKH 185 +++ L NAG+ LD +L+ V +CGH H Sbjct: 131 LDQHSLRNAGE-LDTVLAKFPHVKYLLCGHIH 161 >pir||T35867 hypothetical protein SC9B1.22c - Streptomyces coelicolor >gi|4691401|emb|CAB41568.1| (AL049727) hypothetical protein [Streptomyces coelicolor A3(2)] Length = 273 Score = 69.5 bits (167), Expect = 9e-11 Identities = 60/215 (27%), Positives = 98/215 (44%), Gaps = 31/215 (14%) Query: 4 MLIAHISDTHITNEVAFKSYAYDLIANEINTRP--FDLVIHTGDVTNNGLREEYEHASYL 61 +++AHISD H+ A + + + P D ++ TGD+ ++G EYE A+ + Sbjct: 24 LVLAHISDLHLDGSPRATERA-ERVRERLWRLPGRVDALLVTGDIADHGTEAEYEEAARV 82 Query: 62 LKKIEK----PLIVAPGNHDARNVGYELFEKYI-------GPLIGVYEFKDGVIIWLDST 110 L + P++ PGNHD+R + K + GP V+ F G ++ DS+ Sbjct: 83 LGLRDGSAPFPVLTCPGNHDSRAP----YRKALLGRPAADGPANEVHVFDGGAVLMCDSS 138 Query: 111 IPDLSDGRVGGYKFKWLKAKLEEYSHKKIKIVAAHHHLV----PLPDTGRERNVLFNAGD 166 IP +G + G + W++A L+ ++A HH PLPD+ R R+ + Sbjct: 139 IPGSDEGELDGETYDWIEASLDGLDDGLPALLAFHHPPTPVHHPLPDSYRLRH-----PE 193 Query: 167 VLDLLLSH--DVTLYMCGHKHVP--NVYRVEDLVV 197 L LL + + GH H P V+ LVV Sbjct: 194 RLAALLERRPGIAGLITGHAHSPAATVFAGRPLVV 228 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.141 0.418 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 199545313 Number of Sequences: 2977 Number of extensions: 9085850 Number of successful extensions: 19809 Number of sequences better than 1.0e-10: 9 Number of HSP's better than 0.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 19761 Number of HSP's gapped (non-prelim): 15 length of query: 505 length of database: 189,106,746 effective HSP length: 55 effective length of query: 450 effective length of database: 156,189,961 effective search space: 70285482450 effective search space used: 70285482450 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 167 (69.5 bits)