BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB2302 (moeB) DE:MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN
(MOEB).
         (230 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||D75192 molybdenum cofactor biosynthesis protein (moeb) PAB2...   459  e-128
pir||E71224 probable HESA protein - Pyrococcus horikoshii >gi|32...   422  e-117
pir||E72538 probable HESA protein APE1594 - Aeropyrum pernix (st...   178  5e-44
pir||A70415 molybdopterin biosynthesis protein MoeB - Aquifex ae...   176  3e-43
gi|11498163 thiamine biosynthesis protein (thiF) [Archaeoglobus ...   172  3e-42
gb|AAG18717.1| (AE004976) molybdenum cofactor biosynthesis prote...   167  1e-40
pir||C70921 probable molybdopterin biosynthesis protein moeB - M...   162  2e-39
sp|P46048|HEA2_ANAVA HESA PROTEIN, VEGETATIVE >gi|1075650|pir||S...   162  3e-39
gi|11498142 molybdenum cofactor biosynthesis protein (moeB) [Arc...   162  4e-39
pir||D82801 molybdopterin biosynthesis protein XF0466 [imported]...   160  1e-38
gb|AAD18050.1| (AF124159) molybdopterin synthase sulphurylase [A...   158  6e-38
emb|CAA76284.1| (Y16560) MPT-synthase sulfurylase [Synechococcus...   157  1e-37
gb|AAF52691.1| (AE003621) CG13090 gene product [Drosophila melan...   156  2e-37
pir||A49890 fdxH 5'-region hypothetical protein 1 - Plectonema b...   154  9e-37
sp|P46037|HESA_PLEBO HESA PROTEIN >gi|481924|pir||S40167 hypothe...   154  9e-37
sp|P18500|HESA_ANASP HESA PROTEIN >gi|97697|pir||S11900 hypothet...   150  2e-35
pir||F83381 probable molybdopterin biosynthesis protein MoeB PA2...   149  2e-35
emb|CAC01308.1| (AL390968) putative sulfurylase [Streptomyces co...   148  4e-35
dbj|BAB05138.1| (AP001512) molybdopterin biosynthesis [Bacillus ...   148  5e-35
pir||G70594 probable MOEB- homolog - Mycobacterium tuberculosis ...   147  1e-34
gb|AAD18052.1| (AF124161) molybdopterin synthase sulphurylase [N...   147  1e-34
gb|AAF82644.1|AF167538_11 (AF167538) HesA [Trichodesmium sp. IMS...   146  2e-34
pir||F64621 thiamin biosynthesis protein - Helicobacter pylori (...   146  2e-34
pir||H83062 molybdopterin biosynthesis MoeB protein PA4663 [impo...   146  3e-34
sp|P45211|MOEB_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN >gi...   145  6e-34
pir||S76179 hypothetical protein - Synechocystis sp. (strain PCC...   144  8e-34
gi|7657339 molybdopterin synthase sulfurylase [Homo sapiens] >gi...   144  1e-33
pir||F69659 molybdopterin biosynthesis protein moeB - Bacillus s...   143  1e-33
gb|AAD21552.1| (AF088896) molybdopterin biosynthesis protein [Zy...   143  2e-33
pir||H71891 molybdopterin-synthase sulfurylase - Helicobacter py...   140  2e-32
gb|AAD39225.1|AF149851_6 (AF149851) MoeB-like protein [Pseudomon...   139  3e-32
pir||F82439 molybdopterin biosynthesis MoeB protein VCA0618 [imp...   138  6e-32
pir||E69845 thiamin biosynthesis homolog yjbU - Bacillus subtili...   138  6e-32
gb|AAD21203.1| (AF128444) MoaB [Rhodobacter capsulatus]               137  1e-31
sp|Q56067|MOEB_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN >gi...   133  2e-30
gi|11465801 ORF382 [Porphyra purpurea] >gi|1723404|sp|P51335|YCX...   130  1e-29
sp|P12282|MOEB_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN >gi...   130  2e-29
pir||T32638 hypothetical protein F42G8.6 - Caenorhabditis elegan...   129  2e-29
sp|Q09810|YABA_SCHPO HYPOTHETICAL 44.4 KD PROTEIN C2G11.10C IN C...   128  5e-29
gb|AAC35198.1| (AF003700) HesA [Cyanothece PCC8801]                   128  5e-29
emb|CAB77681.1| (AL161416) molybdopterin synthase sulphurylase [...   128  5e-29
pir||C49695 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate...   128  7e-29
sp|P30138|THIF_ECOLI THIF PROTEIN                                     128  7e-29
pir||C65206 thiF protein - Escherichia coli >gi|396331|gb|AAC430...   126  2e-28
gb|AAC83136.1| (AF109295) MoeB [Staphylococcus carnosus]              126  3e-28
gb|AAF33509.1| (AF170176) 84% identity over 251 amino acids with...   125  3e-28
gb|AAC24520.1| (AF055287) molybdenum cofactor biosynthetic prote...   123  2e-27
gb|AAD17271.1| (AF119361) unknown [Frankia sp. EuIK1]                 123  2e-27
gi|6321903 moeB, thiF, UBA1; Yhr111wp [Saccharomyces cerevisiae]...   122  3e-27
gi|11465494 unknown; protochlorophyllide reductase chlN chain [C...   122  4e-27
pir||B82369 thiF protein VC0063 [imported] - Vibrio cholerae (gr...   119  3e-26
pir||G69076 molybdopterin biosynthesis protein MoeB homolog - Me...   118  7e-26
gb|AAA87953.1| (U47055) HesA [Anabaena PCC7120]                       116  3e-25
pir||H75294 molybdopterin biosynthesis MoeB - Deinococcus radiod...   112  3e-24
emb|CAC11973.1| (AL445065) molybdopterin biosynthesis protein mo...   109  2e-23
pir||B81010 thiF protein NMB2062 [imported] - Neisseria meningit...   108  8e-23
pir||C81953 ThiF protein NMA0373 [imported] - Neisseria meningit...   107  1e-22
gb|AAK40637.1| Thiamine biosynthesis protein related protein (th...   107  1e-22
gb|AAG31053.1|AF264948_15 (AF264948) thiamine biosynthesis prote...    90  2e-17
gb|AAD00512.2| (U81376) PaaA [Erwinia herbicola]                       87  2e-16
gb|AAB37569.1| (U40566) ubiquitin activating enzyme 2 [Arabidops...    86  3e-16
pir||T39623 ubiquitin-activating enzyme e1-like - fission yeast ...    83  3e-15
dbj|BAB15587.1| (AK026904) unnamed protein product [Homo sapiens]      81  1e-14
pir||T38013 hypothetical protein SPAC1A6.10 - fission yeast  (Sc...    81  1e-14
emb|CAA75816.1| (Y15895) ubiquitin activating enzyme [Drosophila...    81  1e-14
gb|AAF58910.1| (AE003832) Uba1 gene product [Drosophila melanoga...    81  1e-14
gb|AAG23434.1|AC078892_6 (AC078892) Ubiquitin activating enzyme ...    80  2e-14
pir||S48571 ubiquitin--protein ligase E1-like protein - yeast (S...    79  4e-14
gi|4507763 ubiquitin-activating enzyme E1 (A1S9T and BN75 temper...    79  5e-14
gb|AAB71466.1| (AC000098) Similar to Caenorhabditis unknown prot...    79  5e-14
dbj|BAB10670.1| (AB025630) gene_id:MPA22.7~pir||T38013~similar t...    79  5e-14
sp|Q29504|UBA1_RABIT UBIQUITIN-ACTIVATING ENZYME E1 >gi|1381183|...    78  7e-14
pir||A38564 ubiquitin--protein ligase (EC 6.3.2.19) E1 - human >...    78  9e-14
gi|6320598 similar to ubiquitin activating enzyme (E1); Uba2p [S...    76  3e-13
pir||T29201 hypothetical protein T03F1.1 - Caenorhabditis elegan...    76  3e-13
emb|CAA40809.1| (X57583) mccB [Escherichia coli]                       76  5e-13
gi|6678483 ubiquitin-activating enzyme E1, Chr X [Mus musculus] ...    75  6e-13
dbj|BAA94076.1| (AB035495) ubiquitin-activating enzyme E1 [Caras...    75  6e-13
gb|AAF25197.1|AF193553_1 (AF193553) ubiquitin-like protein activ...    75  8e-13
gb|AAF50484.2| (AE003556) Uba2 gene product [Drosophila melanoga...    75  8e-13
pir||C81307 probable molybdopterin biosynthesis protein Cj1046c ...    75  1e-12
pir||I49380 ubiquitin-activating enzyme - mouse (fragment) >gi|5...    74  1e-12
gb|AAD23691.1|AC006841_24 (AC006841) putative ubiquitin activati...    74  1e-12
gb|AAF48050.1| (AE003486) CG1749 gene product [Drosophila melano...    74  1e-12
dbj|BAB04974.1| (AP001511) unknown conserved protein [Bacillus h...    74  1e-12
pir||T00587 probable ubiquitin--protein ligase (EC 6.3.2.19) - A...    74  2e-12
pir||T20004 hypothetical protein C47E12.5 - Caenorhabditis elega...    74  2e-12
gb|AAD18053.1| (AF124162) molybdopterin synthase sulphurylase [N...    73  2e-12
gi|6322639 ubiquitin activating enzyme, similar to Uba2p; Uba1p ...    73  3e-12
gi|6755923 ubiquitin activating enzyme E1, Chr Y 1 [Mus musculus...    73  3e-12
gb|AAF00149.1|AF150963_1 (AF150963) ubiquitin-activating enzyme ...    73  3e-12
gb|AAF31704.1|AF218864_1 (AF218864) Smt3 activating enzyme 2 [Dr...    73  3e-12
gb|AAG03059.1|AF288693_1 (AF288693) Ube1l [Mus musculus]               73  3e-12
emb|CAA39056.1| (X55386) ubiquitin-activating enzyme [Saccharomy...    71  9e-12
emb|CAB54319.2| (Z82062) contains similarity to Pfam domain: PF0...    71  9e-12
pir||T51083 related to ubiquitin-activating enzyme homolog UBA2 ...    71  2e-11
sp|P20973|UBA1_WHEAT UBIQUITIN-ACTIVATING ENZYME E1 1 >gi|100841...    70  2e-11
sp|P31252|UBA3_WHEAT UBIQUITIN-ACTIVATING ENZYME E1 3 >gi|743798...    70  3e-11
pir||A48195 ubiquitin--protein ligase E1 homolog - human               69  6e-11
gi|4507767 ubiquitin-activating enzyme E1-like; Ubiquitin-activa...    69  6e-11
pir||T03964 probable ubiquitin--protein ligase (EC 6.3.2.19) - c...    69  6e-11
sp|P31251|UBA2_WHEAT UBIQUITIN-ACTIVATING ENZYME E1 2 >gi|170684...    68  8e-11

>pir||D75192 molybdenum cofactor biosynthesis protein (moeb) PAB2302 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5457496|emb|CAB48987.1| (AJ248283) MOLYBDENUM
           COFACTOR BIOSYNTHESIS PROTEIN (MOEB) [Pyrococcus abyssi]
           Length = 230
           
 Score =  459 bits (1168), Expect = e-128
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MLSESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           MLSESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ
Sbjct: 1   MLSESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
           VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD
Sbjct: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKG 180
           VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKG
Sbjct: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKG 180

Query: 181 KFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           KFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI
Sbjct: 181 KFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230


>pir||E71224 probable HESA protein - Pyrococcus horikoshii
           >gi|3256441|dbj|BAA29124.1| (AP000001) 230aa long
           hypothetical HESA protein [Pyrococcus horikoshii]
           Length = 230
           
 Score =  422 bits (1074), Expect = e-117
 Identities = 201/230 (87%), Positives = 221/230 (95%)

Query: 1   MLSESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           MLSE ELERYDRQIM+FGVEGQEKLK+AKVAV GVGGLGSPVAYYL AAGVGR+LLID+Q
Sbjct: 1   MLSERELERYDRQIMLFGVEGQEKLKRAKVAVAGVGGLGSPVAYYLVAAGVGRVLLIDDQ 60

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
           +PELSNLNRQILHWEED+G+NPKPLSAKWKLE+FNSDV++ET+VGKLTEEN+ +VL GVD
Sbjct: 61  IPELSNLNRQILHWEEDVGKNPKPLSAKWKLERFNSDVRVETYVGKLTEENVNEVLDGVD 120

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKG 180
           VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEG+YGQVTTI+PGKTKRLR+IFP+IKK G
Sbjct: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGMYGQVTTIVPGKTKRLRDIFPKIKKTG 180

Query: 181 KFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           KFPILGATAGVI SIQV EVVKLITGYGEPL NKLL+VDLANN+FEI+EI
Sbjct: 181 KFPILGATAGVIASIQVAEVVKLITGYGEPLLNKLLLVDLANNIFEIVEI 230


>pir||E72538 probable HESA protein APE1594 - Aeropyrum pernix (strain K1)
           >gi|5105281|dbj|BAA80594.1| (AP000062) 267aa long
           hypothetical HESA protein [Aeropyrum pernix]
           Length = 267
           
 Score =  178 bits (447), Expect = 5e-44
 Identities = 99/226 (43%), Positives = 143/226 (62%), Gaps = 2/226 (0%)

Query: 6   ELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELS 65
           +L  Y RQ+ + GV GQ +L  +KVAVVG+GGLG+  A YL A+GVGR++L+D  V E S
Sbjct: 19  DLNVYSRQLGLLGVRGQLRLSSSKVAVVGLGGLGNLAAAYLAASGVGRLILVDRDVVEPS 78

Query: 66  NLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDC 125
           NLNRQ+L+ + D+GR  K ++A  +L + N + +IE     L     ED+    DVIVD 
Sbjct: 79  NLNRQVLYGKGDVGRY-KAVAAAERLGELNPEAEIEPVPEALDPALAEDLAREADVIVDG 137

Query: 126 LDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFP-RIKKKGKFPI 184
           LDN+  R  LD  + + G PLVHGA E ++GQVTT+  G++  L  I P   ++ G   I
Sbjct: 138 LDNWMARLWLDAASWRRGKPLVHGAAERMHGQVTTVERGRSSCLACIAPSNPERAGCTTI 197

Query: 185 LGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           +  T GV+ S++V E +KL+TG GEPL N+L ++DL     E++ +
Sbjct: 198 IAPTVGVVSSLEVLEAIKLLTGVGEPLYNRLAVIDLTTPRIEVLRL 243


>pir||A70415 molybdopterin biosynthesis protein MoeB - Aquifex aeolicus
           >gi|2983752|gb|AAC07312.1| (AE000735) molybdopterin
           biosynthesis protein MoeB [Aquifex aeolicus]
           Length = 271
           
 Score =  176 bits (441), Expect = 3e-43
 Identities = 104/240 (43%), Positives = 144/240 (59%), Gaps = 14/240 (5%)

Query: 3   SESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           +E +++RY R I++   G +GQ KL ++KV V+G GGLGSP  YYL AAGVG I ++D  
Sbjct: 5   TEEQIKRYARHIILPEVGGKGQAKLLQSKVLVIGAGGLGSPALYYLAAAGVGTIGIVDFD 64

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
           V + SNL RQILH  E +G  PK  SAK  LE  N DVK+ T+  K+ + N+ D++   D
Sbjct: 65  VVDFSNLQRQILHTTERVG-TPKVESAKKTLEALNPDVKVITYNTKINKNNVMDIIKDYD 123

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKR----LREIFPRI 176
           VI+D  DNF TR+L++D  +  G PLV  A+    GQ  T+   + K      R +FP  
Sbjct: 124 VILDGTDNFPTRFLINDACYFAGKPLVSAAMLRFEGQ-CTVFDFRDKENSPCYRCLFPEP 182

Query: 177 KKKGKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
              G  P      ILG+  G++GSIQ TE +KL+ G GEPL  KLLI+D  +  F  +++
Sbjct: 183 PPPGLVPSCQEAGILGSVGGIMGSIQATEAIKLLLGIGEPLVGKLLIMDALSMDFRKVKL 242


>gi|11498163 thiamine biosynthesis protein (thiF) [Archaeoglobus fulgidus]
           >gi|7448806|pir||A69319 thiamin biosynthesis protein
           (thiF) homolog - Archaeoglobus fulgidus
           >gi|2650075|gb|AAB90689.1| (AE001066) thiamine
           biosynthesis protein (thiF) [Archaeoglobus fulgidus]
           Length = 267
           
 Score =  172 bits (432), Expect = 3e-42
 Identities = 100/238 (42%), Positives = 139/238 (58%), Gaps = 10/238 (4%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           ML++ +++RY RQI+I   G  GQEKL KAKV VVG GGLGSP   +L AAGVGRI + D
Sbjct: 1   MLNKEQVKRYGRQILIPEIGGRGQEKLLKAKVLVVGAGGLGSPAIEFLAAAGVGRIGIAD 60

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
               +++NL+RQ +H   +LG N K  SA   +EK N DV+++ +   L+ EN  +V+  
Sbjct: 61  GDEVDITNLHRQTIH-AGNLGVN-KAESAASFVEKLNPDVEVDVYPFHLSAENAREVISK 118

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK 178
            DV++DC D+F +R+L++D       P VH AV    GQ+ T+IP +T   R   P    
Sbjct: 119 YDVVLDCTDSFSSRFLINDACVLESKPFVHAAVLRFEGQIMTVIPHETACYRCFLPEAPP 178

Query: 179 KGKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
            G  P      I+G T    G +Q  E +KLI G GE   N+LL  D+ +N F  IE+
Sbjct: 179 PGSVPSCREAGIIGTTTAFFGVLQANEAIKLILGTGELFTNRLLYADILHNDFNFIEV 236


>gb|AAG18717.1| (AE004976) molybdenum cofactor biosynthesis protein; MoeB
           [Halobacterium sp. NRC-1]
           Length = 278
           
 Score =  167 bits (419), Expect = 1e-40
 Identities = 99/238 (41%), Positives = 133/238 (55%), Gaps = 10/238 (4%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L  ++L+RY R I++   G  GQ  L++A V VVG GGLGSPV  YL AAGVG I + D+
Sbjct: 6   LDATQLDRYSRHIIMDDVGATGQAALREAAVLVVGAGGLGSPVIQYLAAAGVGTIGIADD 65

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
              ELSNL RQ +H  +D+G   K  SA   ++  N DV ++    ++T + + D++   
Sbjct: 66  DAVELSNLQRQTIHGTDDVGEQ-KVDSAAAFVDTLNPDVDVQRHDQRVTADTVTDLIAAY 124

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKT-KRLREIFPRIKK 178
           DV+VD  DNF TRYL++D     G+P  HGA+    GQVTT   G      R +FP    
Sbjct: 125 DVVVDASDNFRTRYLINDACTLAGVPFSHGAIFQFEGQVTTFTGGDDGPCYRCLFPEAPP 184

Query: 179 KGKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
            G  P      +LG   G IGSIQ TE VK I G G+ L  +LL  D A+  FE + +
Sbjct: 185 AGTVPDCATAGVLGVLPGTIGSIQATETVKHILGVGDSLDGRLLFYDAADMSFETVAL 242


>pir||C70921 probable molybdopterin biosynthesis protein moeB - Mycobacterium
           tuberculosis (strain H37RV) >gi|2076691|emb|CAB08373.1|
           (Z95150) moeB [Mycobacterium tuberculosis]
           Length = 389
           
 Score =  162 bits (407), Expect = 2e-39
 Identities = 97/237 (40%), Positives = 133/237 (55%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+  E+ RY R ++I   GV GQ++LK A+V  +G GGLGSP   YL AAGVG I +ID 
Sbjct: 14  LTRDEVRRYSRHLIIPDIGVNGQQRLKDARVLCIGAGGLGSPALLYLAAAGVGTIGIIDG 73

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
              + SNL RQI+H   D+GR PK  SA   + + N  V++  +   LT +N  ++    
Sbjct: 74  DHVDESNLQRQIIHGTSDVGR-PKVESAAEAVAEINPHVRVTQYREMLTHDNALEIFGDH 132

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK 179
           D+IVD  DNF TRYL++D A   G P V G++    GQ +   PG+    R + P     
Sbjct: 133 DLIVDGTDNFTTRYLINDAAVLAGKPYVWGSIYRFNGQTSVFWPGRGPCYRCLHPAPPPP 192

Query: 180 GKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           G  P      +LGA    I SIQVTEV+KL+TG G PL  +LL+ +  +  +  I I
Sbjct: 193 GLVPSCAEGGVLGAICATIASIQVTEVLKLLTGVGTPLVGRLLMYEALDATYHQIRI 249


>sp|P46048|HEA2_ANAVA HESA PROTEIN, VEGETATIVE >gi|1075650|pir||S49994 hypothetical
           protein 1 (fdxH2 5' region) - Anabaena variabilis
           >gi|7448802|pir||S70247 hypothetical protein 1 (fdxH2 5'
           region) - Anabaena variabilis >gi|599649|emb|CAA86989.1|
           (Z46890) unknown [Anabaena variabilis]
           Length = 265
           
 Score =  162 bits (406), Expect = 3e-39
 Identities = 91/228 (39%), Positives = 139/228 (60%), Gaps = 5/228 (2%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+ +ELERY RQI++  FG E Q++LK A V V GVGGLG   A YL  AGVGR++L+  
Sbjct: 4   LTSTELERYRRQIILPGFGQEAQQRLKSATVLVTGVGGLGGTAALYLAIAGVGRLILVRG 63

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               L ++NRQIL  ++ +G+ P+   AK +LE  N DV++E     +T +N++ ++   
Sbjct: 64  GELRLDDMNRQILMSDDWVGK-PRVFKAKKRLEDINPDVEVEAIFDYVTPDNVDSLIQSA 122

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK- 178
           DV +DC  NF  R LL+    +   P+V  A++G+   +TTIIPG T  L  +FP   + 
Sbjct: 123 DVALDCAHNFGERDLLNAACVRWRKPMVEAAMDGMDAYLTTIIPGVTPCLSCLFPEKPEW 182

Query: 179 -KGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVF 225
            +  F +LGA +G +  +   E +KLITG+ +PL+++LL ++L    F
Sbjct: 183 DRRGFGVLGAVSGTLACLTALEAMKLITGFSQPLSSELLTMNLHQLTF 230


>gi|11498142 molybdenum cofactor biosynthesis protein (moeB) [Archaeoglobus
           fulgidus] >gi|7448807|pir||C69316 molybdenum cofactor
           biosynthesis protein (moeB) homolog - Archaeoglobus
           fulgidus >gi|2650094|gb|AAB90707.1| (AE001068)
           molybdenum cofactor biosynthesis protein (moeB)
           [Archaeoglobus fulgidus]
           Length = 243
           
 Score =  162 bits (405), Expect = 4e-39
 Identities = 98/216 (45%), Positives = 131/216 (60%), Gaps = 4/216 (1%)

Query: 15  MIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHW 74
           MIFG EGQ +L KAKV VVG GGLGSPV  YL AAGVG+I ++D    E+SNL RQI+H 
Sbjct: 1   MIFGEEGQRRLSKAKVLVVGAGGLGSPVIAYLAAAGVGKIGIVDGDTVEVSNLQRQIIH- 59

Query: 75  EEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLDNFETRYL 134
             +LG N K  SA   ++K N DV+++ +   +T EN+ +V+   DV+  C D+F +R+L
Sbjct: 60  AGNLGEN-KAESAAEFVKKLNPDVEVDVYPFSITPENVLEVVERYDVVAGCPDSFRSRFL 118

Query: 135 LDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFPILGATAGVIGS 194
           L+D    +    VH AV    G+V T   GK    R   P+  ++    ILGATAG  G 
Sbjct: 119 LNDACMILKKTFVHAAVYAWEGEVAT-FTGK-PCYRCYIPKSPEESGRAILGATAGAFGC 176

Query: 195 IQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           +Q  EV+K+ITG GEPL  +L+  +LA   F  I I
Sbjct: 177 LQAAEVIKIITGSGEPLIGRLIRGNLAEMEFFTINI 212


>pir||D82801 molybdopterin biosynthesis protein XF0466 [imported] - Xylella
           fastidiosa (strain 9a5c)
           >gi|9105314|gb|AAF83276.1|AE003897_1 (AE003897)
           molybdopterin biosynthesis protein [Xylella fastidiosa]
           Length = 379
           
 Score =  160 bits (401), Expect = 1e-38
 Identities = 92/236 (38%), Positives = 131/236 (54%), Gaps = 13/236 (5%)

Query: 7   LERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPEL 64
           +ERY R + +   G  GQ++L +A+V ++G GGLGSP A+YLTAAGVG + + D    E 
Sbjct: 116 IERYARHLRLPHIGPHGQQRLAEARVLLIGAGGLGSPAAFYLTAAGVGHLRIADHDTVER 175

Query: 65  SNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVD 124
           SNL RQILH + +LG  PK  SA  +L   N  V++E    +    NIE +L  VDV +D
Sbjct: 176 SNLQRQILHVDAELG-VPKAASAARRLSALNPRVQVEAMQVRANSSNIEALLQDVDVAID 234

Query: 125 CLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFP- 183
             DNF  RYLL+D   K+G PLV+GAV    GQ++    G+ +     +  +  +  +P 
Sbjct: 235 GADNFPARYLLNDACVKMGTPLVYGAVHQFEGQISVFDAGRQRGQAPCYRCLFPEPPYPE 294

Query: 184 ---------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
                    +LG   GVIG +Q TE +KL+   G+PL  ++L  D     F  I +
Sbjct: 295 FAPSCSEAGVLGVLPGVIGMLQATEALKLLLDIGKPLRGRVLCFDALAMQFREIRL 350


>gb|AAD18050.1| (AF124159) molybdopterin synthase sulphurylase [Arabidopsis
           thaliana] >gi|4337042|gb|AAD18051.1| (AF124160)
           molybdopterin synthase sulphurylase [Arabidopsis
           thaliana] >gi|9758110|dbj|BAB08582.1| (AB010071)
           molybdopterin synthase sulphurylase [Arabidopsis
           thaliana]
           Length = 464
           
 Score =  158 bits (395), Expect = 6e-38
 Identities = 91/237 (38%), Positives = 134/237 (56%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS  ++ RY RQ+++  F VEGQ  L K+ V V+G GGLGSP   YL A GVG++ +ID 
Sbjct: 64  LSPDQIYRYSRQLLLPSFAVEGQSNLLKSSVLVIGAGGLGSPALLYLAACGVGQLGIIDH 123

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            V EL+N++RQI+H E  +G +PK  SA       NS +K++ +V  L   N  ++L   
Sbjct: 124 DVVELNNMHRQIIHTEAFIG-HPKVKSAAAACRSINSTIKVDEYVEALRTSNALEILSQY 182

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFP----- 174
           D+IVD  DN  +RY++ D    +G PLV GA  G+ GQ+T          R +FP     
Sbjct: 183 DIIVDATDNPPSRYMISDCCVLLGKPLVSGAALGMEGQLTVYNHNGGPCYRCLFPTPPPT 242

Query: 175 -RIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
              ++     +LG   GVIG +Q  E +KL +  GEPL+ ++L+ D  +    I++I
Sbjct: 243 SACQRCSDSGVLGVVPGVIGCLQALETIKLASLVGEPLSERMLLFDALSARMRIVKI 299


>emb|CAA76284.1| (Y16560) MPT-synthase sulfurylase [Synechococcus PCC7942]
           Length = 391
           
 Score =  157 bits (393), Expect = 1e-37
 Identities = 88/237 (37%), Positives = 138/237 (58%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L++ +  RY R +++   G+EGQ++LK AKV  +G GGLGSP+  YL AAG+GRI ++D 
Sbjct: 11  LTQDDYARYSRHLILPEVGLEGQKRLKAAKVLCIGTGGLGSPLLLYLAAAGIGRIGIVDF 70

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            + + SNL RQ++H    +G+ PK  SAK ++ + N   +++ +   L+ EN   +L   
Sbjct: 71  DIVDHSNLQRQVIHGTSWVGK-PKIESAKNRIHEINPYCQVDLYETALSSENALSILEPY 129

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK 179
           DVIVD  DNF TRYL++D    +G P V+G++    GQ T          R+++P     
Sbjct: 130 DVIVDGTDNFPTRYLVNDACVLLGKPNVYGSIFRFEGQATVFNYEDGPNYRDLYPEPPPP 189

Query: 180 GKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           G  P      +LG   G+IG IQ TE VK+I G G+ L+ +LL+ +  +  F  +++
Sbjct: 190 GMVPSCAEGGVLGILPGIIGVIQATETVKIILGQGQTLSGRLLLYNALDMKFRELKL 246


>gb|AAF52691.1| (AE003621) CG13090 gene product [Drosophila melanogaster]
           Length = 453
           
 Score =  156 bits (391), Expect = 2e-37
 Identities = 95/237 (40%), Positives = 131/237 (55%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+  ++ RY RQ+++  FGV+GQ KLK + V +VG+GGLG P A YL AAG G + L+D 
Sbjct: 64  LTNDDIARYSRQLILPDFGVQGQLKLKNSSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDY 123

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
              E SN +RQILH E+  G + K  SA+  L + N   +I+     L   N   ++ G 
Sbjct: 124 DEVERSNFHRQILHSEDRCGMS-KAESARIALLELNPHCEIQCHSRMLYPHNAMHIIRGY 182

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFP----- 174
           DV++DC DN  TRYLL D    +  PLV G+   + GQ+T          R IFP     
Sbjct: 183 DVVLDCTDNVPTRYLLSDACVMLSKPLVSGSALKMDGQLTVYNYANGPCYRCIFPVPPPP 242

Query: 175 -RIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
             +   G   +LGA  G IG++Q  E +K+I G G+ LA +LLI D  + VF  I I
Sbjct: 243 EAVTNCGDGGVLGAVTGTIGAMQALEAIKVIVGMGDVLAGRLLIFDGGSGVFRNIRI 299


>pir||A49890 fdxH 5'-region hypothetical protein 1 - Plectonema boryanum  (PCC
           73110)
           Length = 277
           
 Score =  154 bits (385), Expect = 9e-37
 Identities = 82/228 (35%), Positives = 135/228 (58%), Gaps = 5/228 (2%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+ +ELERY RQ+M+  F  + Q +LK     V GVGGLG   A YL  AG+G+++L+  
Sbjct: 4   LTPTELERYRRQMMLPGFDEDAQRRLKSFTALVTGVGGLGGTAALYLAVAGIGKLILVRG 63

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               L ++NRQ+L   + +G+ P+   AK  LEK N DV++E     +T +N++ ++   
Sbjct: 64  GELRLDDMNRQVLMTHDTVGQ-PRVFKAKETLEKINPDVEVEAVFDYITPDNVDHLVRST 122

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK- 178
           D+ +DC  NF  R LL++   +   P+V  A++G+   +TTI+PG+T  L  +FP   + 
Sbjct: 123 DITLDCAHNFAERDLLNEACVRYRKPMVEAAMDGMEAYLTTILPGQTGCLTCLFPEKPEW 182

Query: 179 -KGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVF 225
            +  F ++GA +G +  +   E +KLITG+ +PL ++LL ++L    F
Sbjct: 183 DRRGFAVVGAVSGTLACLAALEAIKLITGFEKPLVSELLTMNLGRLEF 230


>sp|P46037|HESA_PLEBO HESA PROTEIN >gi|481924|pir||S40167 hypothetical protein 1 -
           Plectonema boryanum >gi|581441|emb|CAA50696.1| (X71865)
           ORF1 [Plectonema boryanum]
           Length = 277
           
 Score =  154 bits (385), Expect = 9e-37
 Identities = 82/228 (35%), Positives = 135/228 (58%), Gaps = 5/228 (2%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+ +ELERY RQ+M+  F  + Q +LK     V GVGGLG   A YL  AG+G+++L+  
Sbjct: 4   LTPTELERYRRQMMLPGFDEDAQRRLKSFTALVTGVGGLGGTAALYLAVAGIGKLILVRG 63

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               L ++NRQ+L   + +G+ P+   AK  LEK N DV++E     +T +N++ ++   
Sbjct: 64  GELRLDDMNRQVLMTHDTVGQ-PRVFKAKETLEKINPDVEVEAVFDYITPDNVDHLVRST 122

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK- 178
           D+ +DC  NF  R LL++   +   P+V  A++G+   +TTI+PG+T  L  +FP   + 
Sbjct: 123 DITLDCAHNFAERDLLNEACVRYRKPMVEAAMDGMEAYLTTILPGQTGCLTCLFPEKPEW 182

Query: 179 -KGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVF 225
            +  F ++GA +G +  +   E +KLITG+ +PL ++LL ++L    F
Sbjct: 183 DRRGFAVVGAVSGTLACLAALEAIKLITGFEKPLVSELLTMNLGRLEF 230


>sp|P18500|HESA_ANASP HESA PROTEIN >gi|97697|pir||S11900 hypothetical protein 1 -
           Anabaena sp >gi|39032|emb|CAA33558.1| (X15553) hesA
           product (AA 1-266) [Anabaena sp.]
           Length = 266
           
 Score =  150 bits (374), Expect = 2e-35
 Identities = 81/206 (39%), Positives = 122/206 (58%), Gaps = 3/206 (1%)

Query: 17  FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEE 76
           FG   Q++LK A V V GVGGLG   A YL  AGVGR++L+      L ++NRQ+L  ++
Sbjct: 6   FGEAAQKRLKSATVLVTGVGGLGGTAALYLAVAGVGRLILVRGGDLRLDDMNRQVLMTDD 65

Query: 77  DLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLDNFETRYLLD 136
            +G+ P+   AK  L+  N D++IET    +T EN++ ++   D+ +DC  NF  R LL+
Sbjct: 66  WVGK-PRVFKAKETLQAINPDIQIETIHDYITSENVDSLVQSADMALDCAHNFTERDLLN 124

Query: 137 DYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIK--KKGKFPILGATAGVIGS 194
               +   P+V  A++G+   +TTIIPG T  L  IFP      +  F +LGA +G +  
Sbjct: 125 SACVRWRKPMVEAAMDGMEAYLTTIIPGVTPCLSCIFPEKPDWDRRGFSVLGAVSGTLAC 184

Query: 195 IQVTEVVKLITGYGEPLANKLLIVDL 220
           +   E +KLITG+ +PL ++LL +DL
Sbjct: 185 LTALEAIKLITGFSQPLLSQLLTIDL 210


>pir||F83381 probable molybdopterin biosynthesis protein MoeB PA2103 [imported]
           - Pseudomonas aeruginosa (strain PAO1)
           >gi|9948117|gb|AAG05491.1|AE004638_1 (AE004638) probable
           molybdopterin biosynthesis protein MoeB [Pseudomonas
           aeruginosa]
           Length = 392
           
 Score =  149 bits (373), Expect = 2e-35
 Identities = 88/226 (38%), Positives = 130/226 (56%), Gaps = 9/226 (3%)

Query: 2   LSESELERYDRQIMIFGV--EGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS+ E++RY R I + GV  EGQ++LK+A+V ++G GGLGSP   YL AAGVG I L+D 
Sbjct: 13  LSDEEVQRYVRHITLPGVGREGQQRLKQARVLIIGTGGLGSPACLYLAAAGVGTIGLVDF 72

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            V E SNL RQ++H    LG  PK  SA+ +++  N  +++ T    +  +N + ++   
Sbjct: 73  DVVESSNLQRQVVHGYSTLGM-PKVESAQRRMQDLNPYIEVVTHRYAIDADNAQSLIQSY 131

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK 179
           D+++D  DNF TRYL++    K+G PLV GA+    GQV+          + +FP     
Sbjct: 132 DLVLDGTDNFATRYLVNAVCAKLGKPLVFGAIYRFEGQVSVFNLEGGPCYQCLFPNNPPP 191

Query: 180 GKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
              P      ++G   GVIG +Q TE VK + G G+ L+ +LL  D
Sbjct: 192 EMAPSCNAGGVIGVLPGVIGLLQATEAVKALVGLGKSLSGRLLRFD 237


>emb|CAC01308.1| (AL390968) putative sulfurylase [Streptomyces coelicolor A3(2)]
           Length = 392
           
 Score =  148 bits (371), Expect = 4e-35
 Identities = 87/237 (36%), Positives = 129/237 (53%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+  E+ RY R ++I   G++GQ++LK AKV  VG GGLGSP   YL AAGVG + +I+ 
Sbjct: 13  LTVDEVRRYSRHLIIPDVGMDGQKRLKNAKVLAVGAGGLGSPTLMYLAAAGVGTLGIIEF 72

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
              + SNL RQ++H + D+GR PK  SA+  ++  N  V +     +L  +N+ D+    
Sbjct: 73  DEVDESNLQRQVIHSQADIGR-PKAESARDTIQGINPLVDVILHQERLEADNVMDIFSQY 131

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK 179
           D+IVD  DNF TRYL++D    +  P V G++    GQ +          R ++P     
Sbjct: 132 DLIVDGTDNFATRYLVNDACVLLNKPYVWGSIYRFDGQASVFWSEHGPCYRCLYPEPPPP 191

Query: 180 GKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           G  P      +LG     IGSIQ  E +KL+ G GEPL  +L+I D     +  +++
Sbjct: 192 GMVPSCAEGGVLGVLCASIGSIQTNEAIKLLQGIGEPLVGRLMIYDALEMTYRQVKV 248


>dbj|BAB05138.1| (AP001512) molybdopterin biosynthesis [Bacillus halodurans]
           Length = 340
           
 Score =  148 bits (370), Expect = 5e-35
 Identities = 78/223 (34%), Positives = 128/223 (56%), Gaps = 7/223 (3%)

Query: 8   ERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELS 65
           ERY RQ++    G EGQ+KL+ + V +VG+G LG+ +A +   AG+G + ++D    E S
Sbjct: 7   ERYSRQMLFAPIGKEGQQKLQNSAVLIVGIGALGTVLANHFVRAGIGHVRMVDRDYVEAS 66

Query: 66  NLNRQILHWEEDLGRN-PKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVD 124
           NL RQ+L  E D+    PK ++A+ KL+K NSD+K+E  V  +T ENI +++ G+D+++D
Sbjct: 67  NLQRQLLFDENDVRECLPKAVAAQQKLQKVNSDIKVEGIVADVTVENIHELMEGMDLVLD 126

Query: 125 CLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGK--- 181
             DNF+TR+L++D   ++G+P ++G      G     IP KT  LR      +  G+   
Sbjct: 127 GTDNFQTRFLINDACFQMGLPFIYGGAVSSRGMTAMFIPEKTPCLRCFIQEGQGSGQTCD 186

Query: 182 -FPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANN 223
              +LG    ++ S Q  E +K +T   +   + L+  D+  N
Sbjct: 187 TVGVLGPVVDIVASFQAIEALKYLTDNEQAYRHSLMSFDVWRN 229


>pir||G70594 probable MOEB- homolog - Mycobacterium tuberculosis (strain H37RV)
           >gi|2072679|emb|CAB08310.1| (Z95120) moeZ [Mycobacterium
           tuberculosis]
           Length = 392
           
 Score =  147 bits (367), Expect = 1e-34
 Identities = 89/241 (36%), Positives = 129/241 (52%), Gaps = 13/241 (5%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS  E+ RY R ++I   GV+GQ++LK A+V V+G GGLG+P   YL AAGVG I ++D 
Sbjct: 15  LSREEVARYSRHLIIPDLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVDF 74

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            V + SNL RQ++H   D+GR+ K  SA+  +   N  +++     +L   N  D+    
Sbjct: 75  DVVDESNLQRQVIHGVADVGRS-KAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQY 133

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTI----IPGKTKRLREIFPR 175
           D+I+D  DNF TRYL++D A   G P V G++    GQ +        G     R+++P 
Sbjct: 134 DLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAPDGLGVNYRDLYPE 193

Query: 176 IKKKGKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIE 229
               G  P      +LG     + S+  TE +KLITG GE L  +LL+ D     +  I 
Sbjct: 194 PPPPGMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLVYDALEMSYRTIT 253

Query: 230 I 230
           I
Sbjct: 254 I 254


>gb|AAD18052.1| (AF124161) molybdopterin synthase sulphurylase [Nicotiana
           plumbaginifolia]
           Length = 401
           
 Score =  147 bits (367), Expect = 1e-34
 Identities = 87/237 (36%), Positives = 128/237 (53%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS   + RY R +++  FGV+GQ  L K+ V V+G GGLGSP   YL A GVGRI ++D 
Sbjct: 3   LSPDMIYRYSRHLLLPSFGVQGQANLLKSSVLVIGAGGLGSPALLYLAACGVGRIGIVDH 62

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            V EL+NL RQI+H E  +G++ K  SA       NS  +I          N  +++   
Sbjct: 63  DVVELNNLQRQIIHTEAYIGKS-KVKSAAAACRSINSSTQIVEHKEAFRTSNALEIVSKY 121

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFP----- 174
           DV+VD  DN  +RY+++D    +G PL+ GA  GL GQ+T          R +FP     
Sbjct: 122 DVVVDATDNAPSRYMINDCCFVLGKPLISGAALGLEGQLTVYNYNGGPCYRCLFPTPPPT 181

Query: 175 -RIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
              ++     +LG   GVIG +Q  E +K+ +  GEPL+ ++L+ D  +    I++I
Sbjct: 182 NACQRCADSGVLGVVPGVIGCLQALEAIKVASLVGEPLSGRMLLFDALSGRIRIVKI 238


>gb|AAF82644.1|AF167538_11 (AF167538) HesA [Trichodesmium sp. IMS101]
           Length = 273
           
 Score =  146 bits (366), Expect = 2e-34
 Identities = 83/228 (36%), Positives = 132/228 (57%), Gaps = 5/228 (2%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+  ELERY RQ+M+  FG E Q++LK     V GVGGLG  VA YL  AG+G+++L+  
Sbjct: 5   LTPKELERYSRQMMLPGFGEEAQQRLKSTTAVVTGVGGLGGTVALYLAVAGIGKLILVRG 64

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               L ++NRQIL  ++ +G+  +   AK  L   N D++IE     +T EN++ ++   
Sbjct: 65  GELRLDDMNRQILMTDDWVGK-VRVDKAKETLSAINPDIEIEAVPEYVTAENVDPLVQSA 123

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK- 178
           D+ +DC  NF+ R LL+    +   P+V  A+  +   +TTI PGKT  L  +FP   + 
Sbjct: 124 DIAIDCAHNFDERNLLNAACVRWRKPMVEAAMNSMEAYLTTIDPGKTPCLSCLFPEKPQW 183

Query: 179 -KGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVF 225
            +  F +LG  +G +  +  +E +K ITG+ +PL ++LL ++L +  F
Sbjct: 184 DRRGFGVLGIVSGTLACLAASEAIKQITGFSKPLWSQLLTMNLDSMEF 231


>pir||F64621 thiamin biosynthesis protein - Helicobacter pylori (strain 26695)
           >gi|2313946|gb|AAD07863.1| (AE000593) thiamin
           biosynthesis protein (thiF) [Helicobacter pylori 26695]
           Length = 255
           
 Score =  146 bits (365), Expect = 2e-34
 Identities = 91/234 (38%), Positives = 132/234 (55%), Gaps = 7/234 (2%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           MLS  E ERY R IM+   G EGQ KL K+ V V+G GGLGS V  YL AAG+G+I ++D
Sbjct: 1   MLSRLEKERYLRHIMLEDVGEEGQLKLLKSSVLVIGAGGLGSAVLMYLCAAGIGKIGIVD 60

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
             V ++SNL RQI+H ++ L ++ K  SAK +L++ N+ ++IE F  +    N   ++  
Sbjct: 61  FDVVDMSNLQRQIIHSQDFLNQS-KASSAKARLKQLNAGIEIEAFEERFKAHNALSLIEP 119

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK 178
            D I+D  DNF  ++L++D       P  H  V    GQ  +++P  +  L  +F +  K
Sbjct: 120 YDFIIDATDNFNAKFLINDACVLAQKPYSHAGVLEYRGQSMSVLP-HSACLACVFDKPPK 178

Query: 179 KGKFPI---LGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIE 229
           KG  PI    G   GV+G IQ +E +K   G+   L N LLI D+    F+ I+
Sbjct: 179 KGLNPISGLFGVLPGVLGCIQASECLKYFLGFETLLINTLLIADIKTMDFKKIQ 232


>pir||H83062 molybdopterin biosynthesis MoeB protein PA4663 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9950918|gb|AAG08050.1|AE004880_6 (AE004880)
           molybdopterin biosynthesis MoeB protein [Pseudomonas
           aeruginosa]
           Length = 252
           
 Score =  146 bits (364), Expect = 3e-34
 Identities = 86/240 (35%), Positives = 136/240 (55%), Gaps = 13/240 (5%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           MLS+ EL RY RQI++    VEGQ +LK+++  +VG+GGLGSPVA YL AAGVG + L D
Sbjct: 1   MLSDEELLRYSRQILLAQVDVEGQLRLKRSRALIVGLGGLGSPVALYLAAAGVGELHLAD 60

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
               +L+NL RQ++H    +G   K  SA  +L   N  +++ +    L E++++  +  
Sbjct: 61  FDTVDLTNLQRQVIHDGASVGIG-KVESAMRRLGALNPQIRLVSHSAALDEDSLDAAVAA 119

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK 178
           VD+++DC DNF TR  ++    + G PLV GA   L GQ++     + +     +  +  
Sbjct: 120 VDLVLDCTDNFATREAVNVACVRAGKPLVSGAAIRLEGQLSVFDTRRDE--SPCYHCLYG 177

Query: 179 KG--------KFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
            G        +  ++G   G++GS+Q  E +KL+ G+GEPL  +LL+VD     F  + +
Sbjct: 178 HGSEAELTCSEAGVIGPLVGLVGSLQALEALKLLAGFGEPLVGRLLLVDALGTRFRELRV 237


>sp|P45211|MOEB_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN >gi|1075035|pir||C64124
           molybdopterin biosynthesis protein moeB - Haemophilus
           influenzae (strain Rd KW20) >gi|1574288|gb|AAC23099.1|
           (U32823) molybdopterin biosynthesis protein (moeB)
           [Haemophilus influenzae Rd]
           Length = 243
           
 Score =  145 bits (361), Expect = 6e-34
 Identities = 88/234 (37%), Positives = 132/234 (55%), Gaps = 9/234 (3%)

Query: 2   LSESELERYDRQIMIFGVE--GQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS  E  RY+RQI++  V+  GQEKLK +K+ +VG+GGLG   + YL AAGVG + L+D 
Sbjct: 4   LSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTLLDF 63

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               LSNL RQ+LH +  L   PK  SAK  LE+ N  + IET   KL EE + +++   
Sbjct: 64  DTVSLSNLQRQVLHCDARLNM-PKVESAKIALEQINPHINIETINAKLDEEKLAEIIPHF 122

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTI-IPGKTKRLREIFPRIKK 178
           D+++DC DN E R  LD   + + +PL+ GA   + GQV+       T   R++    ++
Sbjct: 123 DIVLDCTDNVEIRNQLDRQCNHMKVPLISGAAIRMEGQVSVFTYEPNTPTYRDLSKLFRQ 182

Query: 179 K----GKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD-LANNVFEI 227
                 +  +L    G++G IQ  E +K+    G+ L  +LL++D  + N+ EI
Sbjct: 183 NVLSCVEAGVLAPIVGIVGCIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREI 236


>pir||S76179 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1653525|dbj|BAA18438.1| (D90914) molybdopterin
           biosynthesis MoeB protein [Synechocystis sp.]
           Length = 392
           
 Score =  144 bits (360), Expect = 8e-34
 Identities = 80/237 (33%), Positives = 135/237 (56%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS+ + +RY R I++   G++GQ+++K A V  +G GGLG+P+  YL AAGVGRI L+D 
Sbjct: 11  LSQDDYQRYSRHIILPEVGLDGQKRIKAASVLCIGSGGLGAPLLLYLAAAGVGRIGLVDF 70

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            + + SNL RQI+H    +G+ PK  SAK  + + N   +++ +  +++  N  D++   
Sbjct: 71  DIVDTSNLQRQIIHGTSWVGK-PKIESAKQSIMEINPFCQVDLYETQISSANALDIIAPY 129

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK 179
           D+++D  DNF TRYL +D    +  P V+G++    GQ T          R+++P     
Sbjct: 130 DIVIDGTDNFPTRYLTNDACVLLNKPNVYGSIFRFEGQATVFNYQGGPNYRDLYPEPPPP 189

Query: 180 GKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
           G  P      +LG   G++G+IQ TE +K+I G    L+ +LL+ +  +  F  +++
Sbjct: 190 GMVPSCSEGGVLGILPGIVGTIQATEALKIILGAPNTLSGRLLLFNAWDMKFRELKL 246


>gi|7657339 molybdopterin synthase sulfurylase [Homo sapiens]
           >gi|11420522|ref|XP_009466.1| molybdopterin synthase
           sulfurylase [Homo sapiens] >gi|3851719|gb|AAC72412.1|
           (AF102544) molybdopterin synthase sulfurylase [Homo
           sapiens] >gi|5817252|emb|CAB53750.1| (AL034553)
           dJ914P20.3 (molybdopterin synthase sulfurylase (MOCS3))
           [Homo sapiens]
           Length = 460
           
 Score =  144 bits (359), Expect = 1e-33
 Identities = 91/237 (38%), Positives = 122/237 (51%), Gaps = 9/237 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS  E+ RY RQ+++   GV GQ +L  A V +VG GGLG P+A YL AAGVGR+ L+D 
Sbjct: 55  LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY 114

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            V E+SNL RQ+LH E  L    K  SA   L + NS V+   +   LT     D++   
Sbjct: 115 DVVEMSNLARQVLHGEA-LAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRY 173

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPR---- 175
           DV+ DC DN  TRYL++D     G PLV  +     GQ+T          R IFP+    
Sbjct: 174 DVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPPPA 233

Query: 176 --IKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
             +       +LG   GV+G +Q  EV+K+  G G   +  LL+ D     F  I +
Sbjct: 234 ETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRL 290


>pir||F69659 molybdopterin biosynthesis protein moeB - Bacillus subtilis
           >gi|2633798|emb|CAB13300.1| (Z99111) molybdopterin
           biosynthesis protein [Bacillus subtilis]
           >gi|3282111|gb|AAC24901.1| (AF012285) molybdopterin
           biosynthesis protein MoeB [Bacillus subtilis]
           Length = 339
           
 Score =  143 bits (358), Expect = 1e-33
 Identities = 92/229 (40%), Positives = 126/229 (54%), Gaps = 19/229 (8%)

Query: 8   ERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELS 65
           ERY RQI     G EGQ++L  + V +VG G LG+  A  L+ AGVG I +ID    E S
Sbjct: 3   ERYSRQIRFKQIGEEGQKRLADSHVLIVGAGALGTAGAEGLSRAGVGTITIIDRDYVEWS 62

Query: 66  NLNRQILHWEEDLG-RNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVD 124
           NL RQ L+ E D   R PK ++AK  L   NS++ IE +V + T E +E ++   DV++D
Sbjct: 63  NLQRQQLYTESDAKLRMPKAMAAKEHLSAINSEIHIEAYVTEGTAETLEPLIEKADVVID 122

Query: 125 CLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFPI 184
             DNFETR L++D A K   P V+GA     G   T+IPG+T  L  +F +I      P+
Sbjct: 123 ATDNFETRMLINDLAQKTKTPWVYGACVSSQGMFMTVIPGETPCLSCLFEQI------PV 176

Query: 185 LGA---TAGVI-------GSIQVTEVVKLITGYGEPLANKLLIVDLANN 223
            GA   TAG+I        + Q  E +KL+TG  E +    +  D+ NN
Sbjct: 177 GGATCDTAGIIPPAVHIVSAYQQAEALKLLTGQKEAIQRGFVTFDVWNN 225


>gb|AAD21552.1| (AF088896) molybdopterin biosynthesis protein [Zymomonas mobilis]
           Length = 251
           
 Score =  143 bits (357), Expect = 2e-33
 Identities = 86/239 (35%), Positives = 134/239 (55%), Gaps = 11/239 (4%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           +L++++L+RY R I++   G +GQ+KL  A VA+VG GG+GSPV  YL AAGVGR+ ++D
Sbjct: 2   ILTDNQLDRYARHIVLPEIGGKGQKKLLSAHVAIVGAGGIGSPVIQYLAAAGVGRLTIVD 61

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
                LSNL RQ L    D+G +   ++A   +++ N DVK+  +  KL  EN + ++  
Sbjct: 62  NDEVSLSNLQRQTLFATRDIGAHKVAMAAN-VVQRLNPDVKVLPYDQKLDAENAKKLIGQ 120

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIF----- 173
            D+IVD  DNF TR ++ D A ++ IPLV  AV     Q+      +  +    F     
Sbjct: 121 ADIIVDGSDNFGTRLVVSDVATELKIPLVSAAVIRFEAQLAVFKGYEASKPYRCFVGDDP 180

Query: 174 --PRIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
             P +    +  +LGA  G IGS+   E ++LIT +G    +KLL++D  +  F  + +
Sbjct: 181 GEPEMTCSSQ-GVLGALTGTIGSLAAIETIRLITRFGSESGDKLLLIDAKDFRFRTVSL 238


>pir||H71891 molybdopterin-synthase sulfurylase - Helicobacter pylori  (strain
           J99) >gi|4155314|gb|AAD06329.1| (AE001506)
           MOLYBDOPTERIN-SYNTHASE SULFURYLASE [Helicobacter pylori
           J99]
           Length = 255
           
 Score =  140 bits (349), Expect = 2e-32
 Identities = 87/234 (37%), Positives = 129/234 (54%), Gaps = 7/234 (2%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           MLS  + ERY R IM+   G EGQ KL K+ V V+G GGLGS V  YL  AG+G+I ++D
Sbjct: 1   MLSRLDKERYLRHIMLEDVGEEGQLKLLKSSVLVIGAGGLGSAVLMYLCTAGIGKIGIVD 60

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
               ++SNL RQI+H  +D   + K  SAK +L++ N+ +++ETF  +    N   ++  
Sbjct: 61  FDSVDMSNLKRQIIH-SQDCLNHSKASSAKARLKQLNAGIEVETFEERFKAHNALPLIEP 119

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK 178
            D I+D  DNF  ++L++D       P  H  V    GQ  +++P  +  L  +F +  K
Sbjct: 120 YDFIIDATDNFNAKFLINDACVLAQKPYSHAGVLKYRGQSMSVLP-HSACLACVFDKPPK 178

Query: 179 KGKFP---ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIE 229
           KG  P   + G   GV+G IQ +E +K   G+   L N LLI D+    F+ I+
Sbjct: 179 KGFNPTSGLWGVLPGVLGCIQASECLKYFLGFETLLINTLLIADIKTMDFKKIQ 232


>gb|AAD39225.1|AF149851_6 (AF149851) MoeB-like protein [Pseudomonas stutzeri KC]
           >gi|6959513|gb|AAF33130.1|AF196567_6 (AF196567) putative
           sulfurylase [Pseudomonas stutzeri]
           Length = 391
           
 Score =  139 bits (346), Expect = 3e-32
 Identities = 87/230 (37%), Positives = 123/230 (52%), Gaps = 13/230 (5%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS +E+ RY R ++I   G+ GQ +LK AKV V+G GGLGSP   YL AAGVG I +ID 
Sbjct: 13  LSRAEINRYSRHLLIPDVGMIGQRRLKNAKVLVIGAGGLGSPTLLYLAAAGVGTIGIIDF 72

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
              + SNL RQ++H  + +G   K  SAK  + + N  V++ET+  +L  +   ++    
Sbjct: 73  DRVDDSNLQRQVIHGVDTVG-ELKVDSAKKAIARLNPFVQVETYTDRLERDMAIELFSRY 131

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRL----REIFPR 175
           D+I+D  DNF TRYL++D       P V G++    GQ +         L    R+++P 
Sbjct: 132 DLIMDGTDNFATRYLVNDACVLANKPYVWGSIFRFEGQASVFWENAPNDLGLNYRDLYPE 191

Query: 176 IKKKGKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
                  P      + G     I SI  TE VKLITG GEPL  +L++ D
Sbjct: 192 PPPPEMAPSCSEGGVFGILCASIASIMATEAVKLITGIGEPLLGRLVVYD 241


>pir||F82439 molybdopterin biosynthesis MoeB protein VCA0618 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9658030|gb|AAF96519.1| (AE004391) molybdopterin
           biosynthesis MoeB protein [Vibrio cholerae]
           Length = 254
           
 Score =  138 bits (344), Expect = 6e-32
 Identities = 84/227 (37%), Positives = 131/227 (57%), Gaps = 9/227 (3%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           +LS++E+ RY+RQI++  F  EGQEKLK++ V ++G GGLG     YL  AG+G I L+D
Sbjct: 5   ILSDAEMLRYNRQIILKAFDFEGQEKLKQSTVLILGAGGLGCASGQYLATAGIGHITLVD 64

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
           + V ELSNL RQ+LH + D+GR  K  SA   L   N  +++ET   +L+++ ++ ++  
Sbjct: 65  DDVVELSNLQRQVLHHDADIGR-AKVDSAADSLRLLNPHLQVETIQARLSDDELDALIAR 123

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTII---PGKT--KRLREIF 173
            D+++D  DN  TR  L+    K   PLV GA   + GQV+      P +   + L  +F
Sbjct: 124 HDLVLDACDNVGTRNQLNRLCFKHKTPLVSGAAIRMEGQVSVFTYQDPAQPCYQCLSALF 183

Query: 174 -PRIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
                   +  I+    G+IG++Q  E +K++T  G P   K+LI+D
Sbjct: 184 GSSALSCVEAGIMAPVVGIIGAVQAMETIKVLTELGTPKQGKILILD 230


>pir||E69845 thiamin biosynthesis homolog yjbU - Bacillus subtilis
           >gi|2633524|emb|CAB13027.1| (Z99110) similar to thiamin
           biosynthesis [Bacillus subtilis]
           Length = 336
           
 Score =  138 bits (344), Expect = 6e-32
 Identities = 83/211 (39%), Positives = 117/211 (55%), Gaps = 19/211 (9%)

Query: 9   RYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSN 66
           RY RQ +    G  GQ+KLK+A+  ++G G LG+  A  L  AGVG + + D    E SN
Sbjct: 4   RYSRQELFAPIGPSGQKKLKEARAVIIGAGALGTASAEMLVRAGVGSVKIADRDYVEWSN 63

Query: 67  LNRQILHWEEDLGRN-PKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDC 125
           L RQ L+ E+D+ +  PK  +A+ +L   NSDV +   V  +T ENI +++    +IVD 
Sbjct: 64  LQRQQLYTEDDVKKEMPKAAAAERRLRSINSDVDVTGLVMDVTAENIFELIRDASIIVDA 123

Query: 126 LDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFPIL 185
            DNFETR +++D A K GIP ++GA  G YG   T++PG T  L  +   +      PI 
Sbjct: 124 ADNFETRLIVNDAAVKEGIPFLYGACVGSYGLTFTVVPGSTPCLHCLLDAL------PIG 177

Query: 186 GATAGVIGSI----------QVTEVVKLITG 206
           GAT    G I          QVT+ +KL+TG
Sbjct: 178 GATCDTAGIISPAVLQVAVFQVTDALKLLTG 208


>gb|AAD21203.1| (AF128444) MoaB [Rhodobacter capsulatus]
           Length = 253
           
 Score =  137 bits (342), Expect = 1e-31
 Identities = 82/220 (37%), Positives = 123/220 (55%), Gaps = 14/220 (6%)

Query: 9   RYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSN 66
           RY R +++   G  GQ +L  A V V+G GGLGSPV  YL AAG+GR+ L D+ V  LSN
Sbjct: 11  RYARHLILPEIGPVGQARLNAASVLVIGAGGLGSPVLLYLAAAGIGRLALADDDVVSLSN 70

Query: 67  LNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCL 126
           L RQ+LH    LG++ K  SA+ +L   N +V+IET   +   E    ++ G D+++DC 
Sbjct: 71  LQRQVLHGTARLGQS-KTASARARLADLNPEVQIETHAIRFGVETAV-LVAGFDLVIDCT 128

Query: 127 DNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGK-------TKRLREIFPRIKKK 179
           DN   R+L++      G+PL+ GA+    GQ+    PG+       T    +  P  + K
Sbjct: 129 DNLAARHLINRACVAAGVPLLSGAIAQWEGQIGLYAPGRGGACYACTFPEPDHLPPAQSK 188

Query: 180 GKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
           G   ++GA  GV+G+    E +K +TG G+ L  +L ++D
Sbjct: 189 G---VVGALPGVVGARMALEAIKHLTGAGQSLLGRLWMID 225


>sp|Q56067|MOEB_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN >gi|1256835|gb|AAA96530.1|
           (U53178) moeB gene product [Salmonella typhimurium]
           Length = 249
           
 Score =  133 bits (332), Expect = 2e-30
 Identities = 78/225 (34%), Positives = 123/225 (54%), Gaps = 8/225 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS+ E+ RY+RQI++  F  EGQE LK A+V VV +GGLG     YL  AGVG++ L+D 
Sbjct: 4   LSDQEILRYNRQIILRGFDFEGQEALKDARVLVVRLGGLGCAATQYLAGAGVGQLTLLDF 63

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               +SNL RQ LH +  +G+ PK  SA+  L + N  + I     +L ++ +  ++ G 
Sbjct: 64  DTVSVSNLQRQTLHSDATVGQ-PKVESARDALARINPHITITPVNARLDDDAMTALIAGH 122

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK 179
            +++DC DN   R  L+   +   +PL+ GA   + GQVT     +T+       R+  +
Sbjct: 123 SLVLDCTDNVSVRNQLNAGCYTAKVPLISGAAIRMEGQVTVFTYRETEPCYRCLSRLFGE 182

Query: 180 GKFP-----ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
                    ++    GVIGS+Q  E +KL+  YG+P + K+++ D
Sbjct: 183 NALTCVEAGVMAPLIGVIGSLQAMEAIKLLAHYGQPASEKIVMYD 227


>gi|11465801 ORF382 [Porphyra purpurea] >gi|1723404|sp|P51335|YCXH_PORPU
           HYPOTHETICAL 43.4 KD PROTEIN IN RPL9-RPL11 INTERGENIC
           REGION (ORF382) >gi|2147563|pir||S73256 hypothetical
           protein 382 - red alga (Porphyra purpurea) chloroplast
           >gi|1276801|gb|AAC08221.1| (U38804) ORF382 [Porphyra
           purpurea]
           Length = 382
           
 Score =  130 bits (324), Expect = 1e-29
 Identities = 76/237 (32%), Positives = 129/237 (54%), Gaps = 10/237 (4%)

Query: 3   SESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           S  E  RY + +++    +EGQE+LK++ +  VG GGLGSP   YL A+G+G+I ++D  
Sbjct: 12  SLEEYTRYSKHLILPQIKLEGQERLKQSSILCVGAGGLGSPALIYLAASGIGKIGIVDND 71

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
           + ++SNL RQIL+   D+G + K   AK K+ + N    ++ F  +L   N  +++   D
Sbjct: 72  IIDISNLQRQILYTVNDIGLS-KAYIAKKKILEINPTCNVQIFNTRLQSINAIEIIRQYD 130

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK- 179
           +I+D  DNF +RY++ D   ++    ++GA+    GQV+T       + R+    I+ + 
Sbjct: 131 IIIDGTDNFGSRYIISDSCLELNKIHIYGAIFQFEGQVSTFNYQGGPKYRDFHNNIETEN 190

Query: 180 ------GKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
                     +LG   G+IG++Q TE +K+I GY   L+  +L  +     FE  +I
Sbjct: 191 NPEDTCSNAGVLGLLPGIIGTLQATEAIKIILGYKSVLSGIILKYNAMTISFEKFKI 247


>sp|P12282|MOEB_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN >gi|78706|pir||B32352
           molybdopterin biosynthesis protein moeB - Escherichia
           coli >gi|145540|gb|AAA23580.1| (M21151) chlN protein
           [Escherichia coli] >gi|1651375|dbj|BAA35514.1| (D90720)
           Molybdopterin biosynthesis MoeB protein. [Escherichia
           coli] >gi|1651378|dbj|BAA35521.1| (D90721) Molybdopterin
           biosynthesis MoeB protein. [Escherichia coli]
           >gi|1787048|gb|AAC73913.1| (AE000185) molybdopterin
           biosynthesis [Escherichia coli K12]
           Length = 249
           
 Score =  130 bits (323), Expect = 2e-29
 Identities = 76/225 (33%), Positives = 121/225 (53%), Gaps = 8/225 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS+ E+ RY+RQI++  F  +GQE LK ++V +VG+GGLG   + YL +AGVG + L+D 
Sbjct: 4   LSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDF 63

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               LSNL RQ LH +  +G+ PK  SA+  L + N  + I      L +  +  ++   
Sbjct: 64  DTVSLSNLQRQTLHSDATVGQ-PKVESARDALTRINPHIAITPVNALLDDAELAALIAEH 122

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK 179
           D+++DC DN   R  L+       +PLV GA   + GQ+T       +       R+  +
Sbjct: 123 DLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQITVFTYQDGEPCYRCLSRLFGE 182

Query: 180 GKFP-----ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
                    ++    GVIGS+Q  E +K++ GYG+P + K+++ D
Sbjct: 183 NALTCVEAGVMAPLIGVIGSLQAMEAIKMLAGYGKPASGKIVMYD 227


>pir||T32638 hypothetical protein F42G8.6 - Caenorhabditis elegans
           >gi|2702447|gb|AAB92067.1| (AF038618) contains
           similarity to the HESA/MOEB/THIF family [Caenorhabditis
           elegans]
           Length = 353
           
 Score =  129 bits (322), Expect = 2e-29
 Identities = 81/228 (35%), Positives = 124/228 (53%), Gaps = 12/228 (5%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           +S+ +  RY RQ+++  FGV GQ+ LK   V +VG GGLG PVA YL AAG+G I ++D 
Sbjct: 10  ISKKDAGRYSRQLLVDDFGVSGQKNLKNLNVLIVGAGGLGCPVATYLGAAGIGTIGIVDY 69

Query: 60  QVPELSNLNRQILHWEEDLGRN-PKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
               L NL+RQ+ + E+ +G++  + L+   KL+  NSD+ ++     L   N   +   
Sbjct: 70  DHISLDNLHRQVAYKEDQVGKSKAQALADNIKLQ--NSDLNVQVHNTSLDSSNAMQLFKN 127

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGK-TKRLREIFP--- 174
            +++ DC DN  TRYL++D    + IPLV G+     GQ++    G      R +FP   
Sbjct: 128 YEIVCDCTDNVATRYLINDVCVLLNIPLVSGSALRWDGQLSVYHYGSDCPCYRCLFPSPP 187

Query: 175 ---RIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
               +    +  +LG   GVIGS+Q  EV+K+       LA +LL+ D
Sbjct: 188 DPNSVTNCNEGGVLGPIVGVIGSMQALEVMKIAAKVRTTLAGQLLLFD 235


>sp|Q09810|YABA_SCHPO HYPOTHETICAL 44.4 KD PROTEIN C2G11.10C IN CHROMOSOME I
           >gi|2130396|pir||S62465 probable molybdopterin synthase
           sulfurylase - fission yeast  (Schizosaccharomyces pombe)
           >gi|1019408|emb|CAA91175.1| (Z54354) similar to yeast
           molybdopterin synthase sulfurylase [Schizosaccharomyces
           pombe]
           Length = 401
           
 Score =  128 bits (319), Expect = 5e-29
 Identities = 80/209 (38%), Positives = 114/209 (54%), Gaps = 7/209 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS  E  RY RQ+++   G+ GQ  LK++ V V+G GGLG P   YL AAG+G + ++D 
Sbjct: 16  LSLDEYSRYGRQMLLSEIGLPGQLSLKRSSVLVIGAGGLGCPAMQYLVAAGIGTLGIMDG 75

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
            V + SNL+RQI+H     G + K +SAK  LE  N +V I T++   +  N+  ++   
Sbjct: 76  DVVDKSNLHRQIIHSTSKQGMH-KAISAKQFLEDLNPNVIINTYLEFASASNLFSIIEQY 134

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPR---- 175
           DV++DC DN  TRYL+ D    +G PLV  +   L GQ+           R +FP     
Sbjct: 135 DVVLDCTDNQYTRYLISDTCVLLGRPLVSASALKLEGQLCIYNYCNGPCYRCMFPNPTPV 194

Query: 176 IKKKGKFPILGATAGVIGSIQVTEVVKLI 204
           +    K  ILG   G +G++Q  E VKLI
Sbjct: 195 VASCAKSGILGPVVGTMGTMQALETVKLI 223


>gb|AAC35198.1| (AF003700) HesA [Cyanothece PCC8801]
           Length = 188
           
 Score =  128 bits (319), Expect = 5e-29
 Identities = 72/175 (41%), Positives = 107/175 (61%), Gaps = 3/175 (1%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+  ELERY RQ+ +  FG +GQ++LK +   V GVGGLG  VA YL  AG+G+++L+  
Sbjct: 3   LTPIELERYSRQMQLPGFGEKGQKQLKASTALVTGVGGLGGTVALYLAVAGIGKLILVRG 62

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
                 +LNRQIL  ++ +G+ P+   AK  L K N DV+IE     +T EN+++++   
Sbjct: 63  GELRRDDLNRQILMTDDWVGK-PRVFKAKETLSKINPDVEIEAVYDYVTPENVDELVQQA 121

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFP 174
           D+ +DC  +F  R LL+    + G P+V  A+ G+   +TTIIPG+T  L  IFP
Sbjct: 122 DIALDCSFDFAERDLLNAACVRWGRPMVEAAMSGMDAYLTTIIPGETPCLSCIFP 176


>emb|CAB77681.1| (AL161416) molybdopterin synthase sulphurylase [Leishmania major]
           Length = 463
           
 Score =  128 bits (319), Expect = 5e-29
 Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 9/224 (4%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L++ ++ER+ RQ+++   G     ++++A V  VG GGLGS +  YL A+GVGR+ ++D 
Sbjct: 22  LTKEDVERFGRQMLVEEIGAAHMGQIRQAHVVCVGAGGLGSTILLYLAASGVGRLTIVDF 81

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
              ELSNL+RQ++H    +G+ PK LSAK    +      ++  V  L+  N E +    
Sbjct: 82  DDVELSNLHRQVIHTTAAIGQ-PKALSAKASCLRLFPAACVDAVVEALSPANAERLFATC 140

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPR---- 175
           DV+VD  DN   RYL++D A + G PLV G+  G  GQ++          R +FP+    
Sbjct: 141 DVVVDGTDNVAARYLINDAAMRCGKPLVSGSAMGWEGQLSVYGYRGGPCYRCLFPQPPPQ 200

Query: 176 --IKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLI 217
             +       ++G   G+IG +Q  EV+K+ TG GE L  +L +
Sbjct: 201 ETVGSCNDSGVMGPLPGMIGCLQALEVLKVATGVGETLNGRLFL 244


>pir||C49695 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis
           protein ThiF - Escherichia coli
           >gi|414234|gb|AAB95618.1| (M88701) thiF [Escherichia
           coli]
           Length = 250
           
 Score =  128 bits (318), Expect = 7e-29
 Identities = 74/225 (32%), Positives = 129/225 (56%), Gaps = 9/225 (4%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           +++ +  RY RQI++    ++GQ+KL  ++V ++G+GGLG+P A YL  AGVG ++L D+
Sbjct: 1   MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADD 60

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               LSNL RQIL   ED+ R PK   ++ +L + N D+++     +LT E ++D +   
Sbjct: 61  DDVHLSNLQRQILFTTEDIDR-PKSQVSQQRLTQLNPDIQLTALQQRLTGEALKDAVARA 119

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTII-PGKTKRLREIFPRIKK 178
           DV++DC DN  TR  ++     +  PL+  +  G  GQ+  +  P +    R ++P  ++
Sbjct: 120 DVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMVLTPPWEQGCYRCLWPDNQE 179

Query: 179 KGK----FPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
             +      ++G   GV+G++Q  E +KL++G   P A +L + D
Sbjct: 180 PERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETP-AGELRLFD 223


>sp|P30138|THIF_ECOLI THIF PROTEIN
           Length = 251
           
 Score =  128 bits (318), Expect = 7e-29
 Identities = 74/225 (32%), Positives = 129/225 (56%), Gaps = 9/225 (4%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           +++ +  RY RQI++    ++GQ+KL  ++V ++G+GGLG+P A YL  AGVG ++L D+
Sbjct: 1   MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADD 60

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               LSNL RQIL   ED+ R PK   ++ +L + N D+++     +LT E ++D +   
Sbjct: 61  DDVHLSNLQRQILFTTEDIDR-PKSQVSQQRLTQLNPDIQLTALQQRLTGEALKDAVARA 119

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTII-PGKTKRLREIFPRIKK 178
           DV++DC DN  TR  ++     +  PL+  +  G  GQ+  +  P +    R ++P  ++
Sbjct: 120 DVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMVLTPPWEQGCYRCLWPDNQE 179

Query: 179 KGK----FPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
             +      ++G   GV+G++Q  E +KL++G   P A +L + D
Sbjct: 180 PERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETP-AGELRLFD 223


>pir||C65206 thiF protein - Escherichia coli >gi|396331|gb|AAC43090.1| (U00006)
           similar to E. coli ChlN [Escherichia coli]
           >gi|1790425|gb|AAC76966.1| (AE000473) thiamin
           biosynthesis, thiazole moiety [Escherichia coli K12]
           Length = 245
           
 Score =  126 bits (314), Expect = 2e-28
 Identities = 74/218 (33%), Positives = 125/218 (56%), Gaps = 9/218 (4%)

Query: 9   RYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSN 66
           RY RQI++    ++GQ+KL  ++V ++G+GGLG+P A YL  AGVG ++L D+    LSN
Sbjct: 2   RYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSN 61

Query: 67  LNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCL 126
           L RQIL   ED+ R PK   ++ +L + N D+++     +LT E ++D +   DV++DC 
Sbjct: 62  LQRQILFTTEDIDR-PKSQVSQQRLTQLNPDIQLTALQQRLTGEALKDAVARADVVLDCT 120

Query: 127 DNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTII-PGKTKRLREIFPRIKKKGK---- 181
           DN  TR  ++     +  PL+  +  G  GQ+  +  P +    R ++P  ++  +    
Sbjct: 121 DNMATRQEINAACVALNTPLITASAVGFGGQLMVLTPPWEQGCYRCLWPDNQEPERNCRT 180

Query: 182 FPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
             ++G   GV+G++Q  E +KL++G   P A +L + D
Sbjct: 181 AGVVGPVVGVMGTLQALEAIKLLSGIETP-AGELRLFD 217


>gb|AAC83136.1| (AF109295) MoeB [Staphylococcus carnosus]
           Length = 333
           
 Score =  126 bits (313), Expect = 3e-28
 Identities = 74/226 (32%), Positives = 124/226 (54%), Gaps = 21/226 (9%)

Query: 8   ERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELS 65
           ERY RQI+    GVEGQEK+ +  V ++G+G LG+ +A  L  AGV ++ ++D    E S
Sbjct: 3   ERYSRQILFKNIGVEGQEKISQKHVLIIGMGALGTHLADGLVRAGVRKLTIVDRDYIEFS 62

Query: 66  NLNRQILHWEEDLGRN-PKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVD 124
           NL RQ ++ E D     PK ++AK +L +  SD++I+ ++ ++    +E+    VD+I+D
Sbjct: 63  NLQRQTMYTENDAKEALPKVIAAKERLTEIRSDIEIDAYIDQVNPPFLEEHAQHVDLILD 122

Query: 125 CLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFPI 184
             DNF+TR L++D+A+K  IP ++G V          IPG+T     + P++      P+
Sbjct: 123 ATDNFDTRLLVNDFAYKYNIPWIYGGVVQSTYIEAAFIPGQTPCFNCVMPQL------PV 176

Query: 185 LGATAGVIG----------SIQVTEVVKLITGYGEPLANKLLIVDL 220
           +  T   +G          S+Q+ + +K++T    P   KL   D+
Sbjct: 177 INMTCDTVGVIQPAVTMTTSLQLRDALKILT--DTPFTPKLTYGDI 220


>gb|AAF33509.1| (AF170176) 84% identity over 251 amino acids with E. coli THIF
           protein (SW:P30138); contains similarity to Pfam domain
           PF00899 (ThiF_family), Score=199.9, E=3.9e-56, N=1
           [Salmonella typhimurium LT2]
           Length = 252
           
 Score =  125 bits (312), Expect = 3e-28
 Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 8/216 (3%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           +++ +  RY RQI++    +EGQ+KL  + V +VG+GGLGSP A YL  AG+G++ L+D+
Sbjct: 1   MNDHDFMRYSRQILLGDIAIEGQQKLLNSHVLIVGLGGLGSPAALYLAGAGIGKLTLVDD 60

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               LSNL RQIL   +D+  +PK  +AK +L + N   K+     +LT + +++ +   
Sbjct: 61  DDVHLSNLQRQILFTTDDIA-HPKAQAAKLRLAQLNPGSKLIVLQQRLTGDVLKNAVAHA 119

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTII-PGKTKRLREIFPRIKK 178
           DV++DC DN  TR  ++     +  PL+  +  G  GQ+  +  P +    R ++P   +
Sbjct: 120 DVVLDCTDNMATRQEINAACVALNTPLISASAVGFGGQLMVLTPPWEQGCYRCLWPDDVE 179

Query: 179 KGK----FPILGATAGVIGSIQVTEVVKLITGYGEP 210
             +      I+G   GV+G++Q  E +KL++G   P
Sbjct: 180 PERNCRTAGIVGPVVGVMGTLQALEAIKLLSGIETP 215


>gb|AAC24520.1| (AF055287) molybdenum cofactor biosynthetic protein [Aspergillus
           nidulans]
           Length = 560
           
 Score =  123 bits (305), Expect = 2e-27
 Identities = 85/224 (37%), Positives = 116/224 (50%), Gaps = 17/224 (7%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L   E  RY RQ+++  FG++GQ KL+ AKV +VG GGLG P A YL  AGVG I L+D 
Sbjct: 139 LHGEEYRRYGRQMIVPQFGLQGQLKLRDAKVLIVGAGGLGCPAALYLAGAGVGTIGLVDG 198

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
              E SNL+RQ+LH   ++G+  K  SA   L + N           LT     D+    
Sbjct: 199 DTVEASNLHRQVLHRSRNVGK-LKVDSAIEYLRELNPHPTYIAHQAHLTPREAPDIFKDY 257

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTI-----IPG-KT--KRLRE 171
           D+I+DC DN  TRYL+ D A  +G PLV  +     GQ+  +      PG KT     R 
Sbjct: 258 DLILDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLMVLNNPPQPPGDKTGGPCYRC 317

Query: 172 IFPR------IKKKGKFPILGATAGVIGSIQVTEVVKLITGYGE 209
           +FP+      +       ILG   G +G +Q +E +K++T  GE
Sbjct: 318 VFPKPPPANSVTSCADGGILGPVVGTMGVLQASEAIKVLTSAGE 361


>gb|AAD17271.1| (AF119361) unknown [Frankia sp. EuIK1]
           Length = 325
           
 Score =  123 bits (305), Expect = 2e-27
 Identities = 82/227 (36%), Positives = 126/227 (55%), Gaps = 10/227 (4%)

Query: 9   RYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSN 66
           RYDRQ+ +  FG   QE+L+ A V V G+GG+G   A YL AAGVGR++L+     E ++
Sbjct: 75  RYDRQLGLPGFGPAAQERLRGATVLVAGIGGVGGAAATYLAAAGVGRLVLVHPGALEEAD 134

Query: 67  LNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTE-ENIEDVLHGVDVIVDC 125
           LNRQ L   E +G   +   A+  L   +  V+I     +L++   +  ++   DV+VD 
Sbjct: 135 LNRQTLMRPEWIG-GSRVACAEQTLRAHHPGVEIVALDRELSQLPELGRLVAEADVVVDA 193

Query: 126 LDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIF----PRIKKKGK 181
             NF  RYLL+D       P V  A+    G +  + PG +  LR +F    P  +  G 
Sbjct: 194 RHNFPDRYLLNDVCVATRTPAVVAAMNATEGNMLVVRPG-SPCLRCVFAEGDPSWQPLG- 251

Query: 182 FPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEII 228
           F +LGA +G++G +  TE +K+I+G+GEP A +LL  DL +  F+++
Sbjct: 252 FTVLGAVSGMVGCLAATEAIKIISGFGEPAAGRLLQFDLWDLDFQVL 298


>gi|6321903 moeB, thiF, UBA1; Yhr111wp [Saccharomyces cerevisiae]
           >gi|731699|sp|P38820|YHR1_YEAST HYPOTHETICAL 49.4 KD
           PROTEIN IN CDC12-ORC6 INTERGENIC REGION
           >gi|630126|pir||S48953 hypothetical protein YHR111w -
           yeast (Saccharomyces cerevisiae)
           >gi|529119|gb|AAB68852.1| (U00059) Yhr111wp
           [Saccharomyces cerevisiae]
           Length = 440
           
 Score =  122 bits (304), Expect = 3e-27
 Identities = 78/215 (36%), Positives = 113/215 (52%), Gaps = 11/215 (5%)

Query: 2   LSESELERYDRQIMIF---GVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           LS  E +RY RQ+++    GV GQ KLK  KV VVG GGLG P   YL  AGVG+I ++D
Sbjct: 39  LSLEEYQRYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVD 98

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
             V E SNL+RQ+LH    +G   K  SA+  + K N  + + T+  +L   N  D+  G
Sbjct: 99  NDVVETSNLHRQVLHDSSRVGM-LKCESARQYITKLNPHINVVTYPVRLNSSNAFDIFKG 157

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIF----- 173
            + I+DC D+  TRYL+ D A  +GI +V  +  G  GQ+T +           F     
Sbjct: 158 YNYILDCTDSPLTRYLVSDVAVNLGITVVSASGLGTEGQLTILNFNNIGPCYRCFYPTPP 217

Query: 174 --PRIKKKGKFPILGATAGVIGSIQVTEVVKLITG 206
               +    +  ++G   G++G++   E +KLI G
Sbjct: 218 PPNAVTSCQEGGVIGPCIGLVGTMMAVETLKLILG 252


>gi|11465494 unknown; protochlorophyllide reductase chlN chain [Cyanidium
           caldarium] >gi|6466397|gb|AAF12979.1|AF022186_102
           (AF022186) unknown; protochlorophyllide reductase chlN
           chain [Cyanidium caldarium]
           Length = 395
           
 Score =  122 bits (303), Expect = 4e-27
 Identities = 74/238 (31%), Positives = 128/238 (53%), Gaps = 9/238 (3%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           +L++ +   Y+RQ+++   G+ GQ  +KK++V  VG G LG+    YL AAG GR+ ++D
Sbjct: 7   ILTDFDYRMYNRQMILPELGLNGQINIKKSRVLCVGAGALGASSLMYLCAAGFGRLGIVD 66

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
                +SNL RQI+H  E +    K  SA   L++ N  +KI+ +  +L+  N   ++  
Sbjct: 67  FDRVAISNLQRQIIHTYEAI-NTYKTFSAFNVLKQLNIHIKIDLYTTRLSSLNAVKLISY 125

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK 178
            D+++D  DNFET+ +++D    +  P+++ AV    GQ++          R I  ++  
Sbjct: 126 YDLVIDASDNFETKCIINDTCQLLKKPMIYAAVLKFIGQISVFNYRGGPSYRTICSKLPD 185

Query: 179 KGKFP------ILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
             +F       ++GA  GV+GS+Q  E VK+I G G+ L+  +L +D+      I  I
Sbjct: 186 SREFASCSESGVIGALPGVLGSLQAIEAVKVIIGKGQVLSGGILTLDVFKMFIRIFGI 243


>pir||B82369 thiF protein VC0063 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9654458|gb|AAF93241.1| (AE004097) thiF
           protein [Vibrio cholerae]
           Length = 258
           
 Score =  119 bits (296), Expect = 3e-26
 Identities = 76/233 (32%), Positives = 123/233 (52%), Gaps = 23/233 (9%)

Query: 1   MLSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           ML++ +  RY RQI +   G EGQ+KL  ++V +VG GGLG+ VA YL  AGVG++++ D
Sbjct: 1   MLTDKQFLRYQRQISLAELGEEGQQKLLNSRVLIVGCGGLGNVVAPYLVGAGVGQVIIAD 60

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
               EL NL+RQI + E  +G N   L A++ L + NS+V++     ++ E  +   ++ 
Sbjct: 61  SDRLELHNLHRQICYHEAQIGHNKAELLARY-LRELNSEVRVRVIAREVDELILNLEINQ 119

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTT------------IIPGKT 166
           VD+++DC DN  TR+ ++   +    PL+ GAV G  G +              ++P   
Sbjct: 120 VDLVLDCSDNLPTRHAINRACYAAQRPLISGAVIGWEGHLMAFDYRQSTPCYQCVVPDMA 179

Query: 167 KRLREIFPRIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVD 219
           +R      R   +G   ++G   G+IG+ Q    +  + G     AN+LL  D
Sbjct: 180 ER-----QRCSDRG---VIGPVVGMIGNGQALIALHALMGSAHFPANQLLRFD 224


>pir||G69076 molybdopterin biosynthesis protein MoeB homolog - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622694|gb|AAB86045.1| (AE000917) molybdopterin
           biosynthesis protein MoeB homolog [Methanobacterium
           thermoautotrophicum]
           Length = 251
           
 Score =  118 bits (292), Expect = 7e-26
 Identities = 80/240 (33%), Positives = 122/240 (50%), Gaps = 18/240 (7%)

Query: 8   ERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNL 67
           E   RQ+ +     Q KLK + V+V+G GG+G      L   GVG + +ID  V ++SN+
Sbjct: 12  EMVSRQMGLLSRADQLKLKDSTVSVIGCGGIGGAAVEMLARMGVGSLRIIDSDVFDVSNI 71

Query: 68  NRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLD 127
           NRQ++    DL R PK   A  ++   N   +++ +     EEN  +++ G D +VD LD
Sbjct: 72  NRQLMSSFRDL-RIPKVDVAAERIRTVNPFSRVKVYHEIFDEENAAEIIPGSDAVVDALD 130

Query: 128 NFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK-----RL----REIFPRIKK 178
           N  +R +        GIP +HGA+ G  GQVT    G        RL     E+   +K 
Sbjct: 131 NITSRVIASRRCTSEGIPFIHGAIHGSMGQVTVFREGSPSYEELFRLPSVGLELTADVKA 190

Query: 179 KGKF------PILGATAGVIGSIQVTEVVKLITGYGEPL-ANKLLIVDL-ANNVFEIIEI 230
           K +       P++G  A + G +Q  EV+KLITG G+ + A ++L  DL     F+I+E+
Sbjct: 191 KLRDLSSKTPPVIGPVANITGCLQAAEVLKLITGRGDVIAAPRMLKFDLFQGEPFKIVEL 250


>gb|AAA87953.1| (U47055) HesA [Anabaena PCC7120]
           Length = 159
           
 Score =  116 bits (287), Expect = 3e-25
 Identities = 62/155 (40%), Positives = 95/155 (61%), Gaps = 3/155 (1%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           L+ +ELERY RQ+M+  FG   Q++LK A V V GVGGLG   A YL  AGVGR++L+  
Sbjct: 4   LTPTELERYSRQMMLPNFGEAAQKRLKSATVLVTGVGGLGGTAALYLAVAGVGRLILVRG 63

Query: 60  QVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGV 119
               L ++NRQ+L  ++ +G+ P+   AK  L+  N D++IET    +T EN++ ++   
Sbjct: 64  GDLRLDDMNRQVLMTDDWVGK-PRVFKAKETLQAINPDIQIETIHDYITSENVDSLVQSA 122

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGL 154
           D+ +DC  NF  R LL+    +   P+V  A++G+
Sbjct: 123 DMALDCAHNFTERDLLNSACVRWRKPMVEAAMDGM 157


>pir||H75294 molybdopterin biosynthesis MoeB - Deinococcus radiodurans  (strain
           R1) >gi|6460075|gb|AAF11815.1|AE002059_5 (AE002059)
           molybdopterin biosynthesis MoeB [Deinococcus
           radiodurans]
           Length = 235
           
 Score =  112 bits (278), Expect = 3e-24
 Identities = 76/235 (32%), Positives = 118/235 (49%), Gaps = 10/235 (4%)

Query: 2   LSESELERYDRQIMI---FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLID 58
           L+  EL R  R +++        QEKL+ A+V VVG GGLG PV   L  AGVG + + D
Sbjct: 3   LTREELRRVSRPLLVPEWAEAGAQEKLRAARVLVVGAGGLGGPVIRQLAGAGVGALTVAD 62

Query: 59  EQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG 118
                ++NL+RQ L+   D+GR+ K  +A    +  N  V+I+     LT E    ++  
Sbjct: 63  GDTVSVTNLHRQQLYRTADVGRS-KAETACAVAQGVNPFVQIQA-APALTPETAPTLIAA 120

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKK 178
            D+ VD  DNFETRYL+ D   ++G   V GA  G+ G  +    G    LR++FP  + 
Sbjct: 121 HDLTVDATDNFETRYLIADTCRELGREWVWGAASGVSGLCSVF--GPHLGLRDVFPTPED 178

Query: 179 KG---KFPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFEIIEI 230
                +  +LG    ++G +   + + ++ G GEPL  KL   D       ++++
Sbjct: 179 DSSCDELGVLGPVPNLVGDLMALQALLVLGGVGEPLRGKLWTFDALTGRVRVLKM 233


>emb|CAC11973.1| (AL445065) molybdopterin biosynthesis protein moeB related protein
           [Thermoplasma acidophilum]
           Length = 261
           
 Score =  109 bits (271), Expect = 2e-23
 Identities = 70/207 (33%), Positives = 115/207 (54%), Gaps = 13/207 (6%)

Query: 9   RYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSN 66
           +Y RQ+++  F  +   K+++A++ VVG+GG+GS +A  L  +GV +++LID      SN
Sbjct: 7   KYARQMVLRQFDKDDIAKIRRARILVVGLGGVGSLIADLLVRSGVKKVVLIDRDYVSSSN 66

Query: 67  LNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCL 126
           L RQ L+ EED+G + K  +AK +L+K N++V++E         N E ++  VD+++D  
Sbjct: 67  LYRQTLYSEEDIG-DSKVEAAKRRLQKVNTEVEVEAINETFDATNAEALVSSVDLVMDGT 125

Query: 127 DNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIF-------PRIKKK 179
           DN  +R +++D   K+  P V  +    YGQV  +IP KT   R  F       P   + 
Sbjct: 126 DNLTSRLIINDACVKLKRPWVMASAIETYGQVKAVIPEKTSCYRCYFTSEPFAQPTCAEV 185

Query: 180 GKFPILGATAGVIGSIQVTEVVKLITG 206
           G   +L +    I SI  T  +K++TG
Sbjct: 186 G---VLNSLVTAISSIAFTLAMKILTG 209


>pir||B81010 thiF protein NMB2062 [imported] - Neisseria meningitidis  (group B
           strain MD58) >gi|7227324|gb|AAF42381.1| (AE002556) thiF
           protein [Neisseria meningitidis MC58]
           Length = 256
           
 Score =  108 bits (266), Expect = 8e-23
 Identities = 69/221 (31%), Positives = 106/221 (47%), Gaps = 13/221 (5%)

Query: 7   LERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPEL 64
           L RY R I++   G+EGQ+KL  A + VVG GGLG+    YL A+GVG + + D    EL
Sbjct: 13  LLRYSRHILLDEIGIEGQQKLSAAHILVVGCGGLGAAALPYLAASGVGTLTIADSDTVEL 72

Query: 65  SNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVD 124
            NL RQ+   E D+G+  K  +   +L++ N  V +     KL    +  ++   D+++D
Sbjct: 73  HNLQRQVAFDEGDVGK-LKTEALAGRLKRINHTVNVRAVNEKLDGCRLTGLVQAADIVLD 131

Query: 125 CLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGK--- 181
           C DN+ TR  ++    +   PLV GA     GQ+    P         +  +   G    
Sbjct: 132 CCDNYATRQAVNRACVQTKTPLVSGAAVRFEGQLAVYRPDLPD--SPCYACLFDGGSASD 189

Query: 182 -----FPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLI 217
                F +     G+IGS Q  E +K++   GEP   +L +
Sbjct: 190 GICSLFGVFSPLVGIIGSTQAAEALKILLDAGEPSHGRLAV 230


>pir||C81953 ThiF protein NMA0373 [imported] - Neisseria meningitidis  (group A
           strain Z2491) >gi|7379126|emb|CAB83674.1| (AL162753)
           ThiF protein [Neisseria meningitidis Z2491]
           Length = 256
           
 Score =  107 bits (265), Expect = 1e-22
 Identities = 69/221 (31%), Positives = 104/221 (46%), Gaps = 13/221 (5%)

Query: 7   LERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPEL 64
           L RY R I++   G+EGQ+KL  A + VVG GGLG+    YL A+G+G + + D    EL
Sbjct: 13  LLRYSRHILLDEIGIEGQQKLSAAHILVVGCGGLGAAALPYLAASGIGTLTIADSDTVEL 72

Query: 65  SNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVD 124
            NL RQ+   E D+G+      A  +L   N  V + T   KL    +  ++   D+++D
Sbjct: 73  HNLQRQVAFDEGDVGKLKTEALAD-RLRHINHTVDVRTINEKLDGCRLTGLVQAADIVLD 131

Query: 125 CLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGK--- 181
           C DN+ TR  ++    +   PLV GA     GQ+    P         +  +   G    
Sbjct: 132 CCDNYATRQAVNRACVQAKTPLVSGAAVRFEGQLAVYRPDLPD--SPCYACLFDGGSASD 189

Query: 182 -----FPILGATAGVIGSIQVTEVVKLITGYGEPLANKLLI 217
                F +     G+IGS Q  E +K++   GEP   +L +
Sbjct: 190 GICSLFGVFSPLVGIIGSTQAAEALKILLDAGEPSHGRLAV 230


>gb|AAK40637.1| Thiamine biosynthesis protein related protein (thiF) [Sulfolobus
           solfataricus]
           Length = 333
           
 Score =  107 bits (265), Expect = 1e-22
 Identities = 57/163 (34%), Positives = 93/163 (56%), Gaps = 1/163 (0%)

Query: 7   LERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSN 66
           +ERY RQ+++ G+  Q++L + K+ + G G LG+ VA  L   GV  + ++D  V +++N
Sbjct: 43  VERYSRQLIVLGLGIQQRLNELKILIAGCGALGTAVAELLARLGVKELTIVDADVVDITN 102

Query: 67  LNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCL 126
           L+R  L  E D+G+    + AK K+   NS +KI   +  L EEN+E ++   D + D L
Sbjct: 103 LHRVHLFDENDVGKPKAEVCAK-KISLINSSIKINYIIDILDEENVERLISDKDYVFDAL 161

Query: 127 DNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRL 169
           D+   + LL+D   K+G  L++G + G YG    I P +T  L
Sbjct: 162 DSLYYKLLLNDAIVKLGKILIYGGINGEYGSAKLIDPSQTSCL 204


>gb|AAG31053.1|AF264948_15 (AF264948) thiamine biosynthesis protein ThiF [Erwinia amylovora]
           Length = 321
           
 Score = 90.5 bits (221), Expect = 2e-17
 Identities = 64/207 (30%), Positives = 96/207 (45%), Gaps = 8/207 (3%)

Query: 7   LERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPEL 64
           + RY RQ M+   G  GQ++L +A+V V+G GGLGS +   L AAG G + L D    E 
Sbjct: 1   MSRYQRQSMLPEIGESGQQRLAQARVLVIGAGGLGSALLPLLAAAGAGYLRLYDGDRVEE 60

Query: 65  SNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVD 124
            NL+RQ L+  +D+G   K   A+  L   N    ++     LT       L G+D+ +D
Sbjct: 61  HNLHRQTLYGMQDIGEE-KVFCARRALAIRNPACVVDARPHALTASATAAALDGIDLAID 119

Query: 125 CLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKK----G 180
             DNF   Y L D      IPLV  +V G  G V     G     R +FP++        
Sbjct: 120 AADNFALTYQLSDACLAHRIPLVSASVLGRRGYVGGFC-GGAPSYRALFPQLPGSAANCN 178

Query: 181 KFPILGATAGVIGSIQVTEVVKLITGY 207
              ++G     +G++Q    + ++  +
Sbjct: 179 TAGVMGPAVATLGAMQAQMALSILLNF 205


>gb|AAD00512.2| (U81376) PaaA [Erwinia herbicola]
           Length = 373
           
 Score = 86.6 bits (211), Expect = 2e-16
 Identities = 74/266 (27%), Positives = 123/266 (45%), Gaps = 47/266 (17%)

Query: 1   MLSESELERYDRQIMIFGVEG---------QEKLKKAKVAVVGVGGLGSPVAYYLTAAGV 51
           +LS  E+ERY+RQI+ F +           QE+LK++KVA+ G+GG G+  A  L  +G+
Sbjct: 97  VLSGEEVERYNRQILQFSLIDADNQHPFVYQERLKQSKVAIFGMGGWGTWCALQLAMSGI 156

Query: 52  GRILLIDEQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETF-------- 103
           G + LID    ELSN+NRQ+L+  +D+G+N K  +AK  +  +N +V +ETF        
Sbjct: 157 GTLRLIDGDDVELSNINRQVLYRTDDVGKN-KVDAAKDTILAYNENVHVETFFEFASPDR 215

Query: 104 -------------------VGKLTEENIEDVLHGV---------DVIVDCLDNFETRYLL 135
                              +G   ++  E+++H +         ++  D L+       L
Sbjct: 216 ARLEELVGDSTFIILAWAALGYYRKDTAEEIIHSIAKDKAIPVIELGGDPLEISVGPIYL 275

Query: 136 DDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFPILGATAGVIGSI 195
           +D  H     + +   +  Y   + I   +  RL+  F    +K        +  ++  I
Sbjct: 276 NDGVHSGFDEVKNSVKDKYYDSNSDIRKFQEARLKHSFIDGDRKVNAWQSAPSLSIMAGI 335

Query: 196 QVTEVVKLITGYGEP-LANKLLIVDL 220
              +VVK ITGY +P L  K  I+ L
Sbjct: 336 VTDQVVKTITGYDKPHLVGKKFILSL 361


>gb|AAB37569.1| (U40566) ubiquitin activating enzyme 2 [Arabidopsis thaliana]
           >gi|9758426|dbj|BAB08968.1| (AB006700) ubiquitin
           activating enzyme 2 [Arabidopsis thaliana]
           Length = 1077
           
 Score = 86.2 bits (210), Expect = 3e-16
 Identities = 55/157 (35%), Positives = 88/157 (56%), Gaps = 7/157 (4%)

Query: 4   ESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPE 63
           E + + + RQ+ ++G E   KL  + V + G+ GLG  +A  +  AGV  + L DE V E
Sbjct: 69  EIDEDLHSRQLAVYGRETMRKLFASNVLISGMQGLGVEIAKNIILAGVKSVTLHDENVVE 128

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIV 123
           L +L+   +  EED+G+N + L++  KL++ N+ V + T  GKLT+E + D    V V V
Sbjct: 129 LWDLSSNFVFTEEDIGKN-RALASVHKLQELNNAVAVSTLTGKLTKEQLSD--FQVVVFV 185

Query: 124 DCLDNFETRYLLDDY--AHKVGIPLVHGAVEGLYGQV 158
           D   +FE    +DDY  +H+  I  +   V GL+G +
Sbjct: 186 DI--SFEKATEIDDYCHSHQPPIAFIKADVRGLFGSL 220


 Score = 69.5 bits (167), Expect = 3e-11
 Identities = 55/168 (32%), Positives = 78/168 (45%), Gaps = 10/168 (5%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD QI +FG   Q+KL+ A+V VVG G LG      L   GV     G++ + D+ V E
Sbjct: 471 RYDAQISVFGSTLQKKLEDARVFVVGAGALGCEFLKNLALMGVSCGTQGKLTVTDDDVIE 530

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETF---VGKLTEENIEDVL-HGV 119
            SNL+RQ L  + ++G+  K   A       NS + I+     VG  TE   +D     +
Sbjct: 531 KSNLSRQFLFRDWNIGQ-AKSTVAATAAAGINSRLNIDALQNRVGPETENVFDDSFWENL 589

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            V+V+ LDN   R  +D        PL+     G       +IP  T+
Sbjct: 590 TVVVNALDNVTARLYVDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTE 637


>pir||T39623 ubiquitin-activating enzyme e1-like - fission yeast
           (Schizosaccharomyces pombe) >gi|2956755|emb|CAA17901.1|
           (AL022104) ubiquitin-activating enzyme e1-like
           [Schizosaccharomyces pombe]
           Length = 628
           
 Score = 83.1 bits (202), Expect = 3e-15
 Identities = 49/150 (32%), Positives = 75/150 (49%), Gaps = 2/150 (1%)

Query: 19  VEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDL 78
           VE     K AKV +VG GG+G  +   L  +GV  + +ID    +LSNLNRQ L  ++ +
Sbjct: 17  VEALRNFKSAKVLLVGAGGIGCELLKNLLMSGVKEVHIIDLDTIDLSNLNRQFLFRKKHV 76

Query: 79  GRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDV-LHGVDVIVDCLDNFETRYLLDD 137
            + PK + A      FN +VK+E +   + E+          D++ + LDN + R  ++ 
Sbjct: 77  -KQPKAIVAAKTASSFNPNVKLEAYHANIKEDRFNVAWFRQFDLVFNALDNLDARRHVNK 135

Query: 138 YAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
                 +PL+     G  GQV  II GKT+
Sbjct: 136 QCLLASVPLIESGTTGFLGQVQVIIHGKTE 165


>dbj|BAB15587.1| (AK026904) unnamed protein product [Homo sapiens]
           Length = 404
           
 Score = 80.8 bits (196), Expect = 1e-14
 Identities = 62/216 (28%), Positives = 102/216 (46%), Gaps = 29/216 (13%)

Query: 19  VEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDL 78
           V   EK++   VA+VGVGG+GS  A  LT  G+G++LL D    EL+N+NR  L ++   
Sbjct: 65  VSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNR--LFFQPHQ 122

Query: 79  GRNPKPLSAKWKLEKFNSDVKIET-------------FVGKLTEENIEDVLHGVDVIVDC 125
               K  +A+  L   N DV  E              F+ +++   +E+    VD+++ C
Sbjct: 123 AGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEG-KPVDLVLSC 181

Query: 126 LDNFETRYLLDDYAHKVGIPLVHGAV--EGLYGQVTTIIPGKTKRLREIFP--------- 174
           +DNFE R  ++   +++G   +   V    + G +  IIPG++       P         
Sbjct: 182 VDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAANIDE 241

Query: 175 -RIKKKGKFPI-LGATAGVIGSIQVTEVVKLITGYG 208
             +K++G     L  T GV+  I V  V+K +  +G
Sbjct: 242 KTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFG 277


>pir||T38013 hypothetical protein SPAC1A6.10 - fission yeast
           (Schizosaccharomyces pombe) >gi|2414593|emb|CAB16360.1|
           (Z99258) hypothetical protein [Schizosaccharomyces
           pombe]
           Length = 485
           
 Score = 80.8 bits (196), Expect = 1e-14
 Identities = 58/220 (26%), Positives = 106/220 (47%), Gaps = 12/220 (5%)

Query: 8   ERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNL 67
           E+  R    FG +G E+L+ + V VVG GG+GS V   L  +GV +I ++D     LS+L
Sbjct: 107 EQLARNYAFFGEDGMERLRNSFVIVVGCGGVGSWVINMLARSGVQKIRIVDFDQVSLSSL 166

Query: 68  NRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG-VDVIVDCL 126
           NR  +   +D+G  PK L+ K  ++KF   ++++        ++ +D+L G  D ++D +
Sbjct: 167 NRHSIATLQDVG-TPKTLAIKKAIKKFAPWIEVDARNALFNPDSADDLLSGNPDFVIDAI 225

Query: 127 DNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFPILG 186
           DN +T+  L  Y +   +P++           +T    K+   R     I    + P+  
Sbjct: 226 DNIQTKVDLLSYCYNHKLPVI----------ASTGSACKSDPTRVNIADISATSEDPLSR 275

Query: 187 ATAGVIGSIQVTEVVKLITGYGEPLANKLLIVDLANNVFE 226
           AT   +  + + E + ++    +P   K  ++ L+   FE
Sbjct: 276 ATRRRLRLLGIMEGIPVVFSTEKPDPRKASLLPLSEEEFE 315


>emb|CAA75816.1| (Y15895) ubiquitin activating enzyme [Drosophila melanogaster]
           Length = 1008
           
 Score = 80.8 bits (196), Expect = 1e-14
 Identities = 57/167 (34%), Positives = 84/167 (50%), Gaps = 9/167 (5%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV----GRILLIDEQVPEL 64
           RYD QI IFG + QEKL  +K  +VG G +G  +       G+    G+I + D  + E 
Sbjct: 403 RYDSQIAIFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEK 462

Query: 65  SNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETF---VGKLTEENI-EDVLHGVD 120
           SNLNRQ L    D+ + PK ++A   +++ N +V +  +   VG  TE+   ED    +D
Sbjct: 463 SNLNRQFLFRPHDV-QKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLD 521

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            + + LDN + R  +D       IPLV     G  G V  I+P  T+
Sbjct: 522 GVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATE 568


>gb|AAF58910.1| (AE003832) Uba1 gene product [Drosophila melanogaster]
           Length = 1008
           
 Score = 80.8 bits (196), Expect = 1e-14
 Identities = 57/167 (34%), Positives = 84/167 (50%), Gaps = 9/167 (5%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV----GRILLIDEQVPEL 64
           RYD QI IFG + QEKL  +K  +VG G +G  +       G+    G+I + D  + E 
Sbjct: 403 RYDSQIAIFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEK 462

Query: 65  SNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETF---VGKLTEENI-EDVLHGVD 120
           SNLNRQ L    D+ + PK ++A   +++ N +V +  +   VG  TE+   ED    +D
Sbjct: 463 SNLNRQFLFRPHDV-QKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLD 521

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            + + LDN + R  +D       IPLV     G  G V  I+P  T+
Sbjct: 522 GVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATE 568


>gb|AAG23434.1|AC078892_6 (AC078892) Ubiquitin activating enzyme [Leishmania major]
           Length = 673
           
 Score = 80.0 bits (194), Expect = 2e-14
 Identities = 53/167 (31%), Positives = 83/167 (48%), Gaps = 10/167 (5%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD  I IFG   Q+ L+  ++ +VG G LG          G+     G +++ D    E
Sbjct: 468 RYDHIISIFGKGFQQLLQNLRLFMVGCGALGCENVKNFALCGITCGTGGSLVVTDNDRIE 527

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIET---FVGKLTEENIEDVL-HGV 119
           +SNL+RQ L  EE++G++ K  +A  ++ + N D  ++    F+G  TE    D     +
Sbjct: 528 VSNLSRQFLFREENVGQS-KSAAATARMRQMNPDANVDARQDFIGTTTEHLYPDTFWQSL 586

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKT 166
           +V+V+ LDN E R  +D    +    LV     G  G V  I+PG+T
Sbjct: 587 NVVVNALDNIEARLYVDQQCVRFQKVLVEAGTMGTGGNVDIIVPGRT 633


>pir||S48571 ubiquitin--protein ligase E1-like protein - yeast (Saccharomyces
           cerevisiae) >gi|475916|emb|CAA82980.1| (Z30326)
           ubiquitin activating enzyme E1-like protein
           [Saccharomyces cerevisiae]
           Length = 294
           
 Score = 79.2 bits (192), Expect = 4e-14
 Identities = 48/166 (28%), Positives = 86/166 (50%), Gaps = 4/166 (2%)

Query: 4   ESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPE 63
           E ++ R    + I G +  +KL+ ++  +VG GG+GS +   +     G I ++D    +
Sbjct: 31  EKKMPRETSLVTIIGEDSYKKLRSSRCLLVGAGGIGSELLKDIILMEFGEIHIVDLDTID 90

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDV--LHGVDV 121
           LSNLNRQ L  ++D+ + PK  +A   ++ FN+  K+  + G L + +   +      D+
Sbjct: 91  LSNLNRQFLFRQKDI-KQPKSTTAVKAVQHFNNS-KLVPYQGNLMDISTFPLHWFEQFDI 148

Query: 122 IVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
           I + LDN   R  ++  +  + +PL+     G  G +  IIPGKT+
Sbjct: 149 IFNALDNLAARRYVNKISKFLSLPLIESGTAGFDGYMQPIIPGKTE 194


>gi|4507763 ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature
           sensitivity complementing); Ubiquitin-activating enzyme
           E1 (teA1S9) [Homo sapiens]
           >gi|267189|sp|P22314|UBA1_HUMAN UBIQUITIN-ACTIVATING
           ENZYME E1 (A1S9 PROTEIN) >gi|478678|pir||S23770
           ubiquitin-activating enzyme E1 - human
           >gi|35830|emb|CAA40296.1| (X56976) ubiquitin activating
           enzyme E1 [Homo sapiens]
           Length = 1058
           
 Score = 78.8 bits (191), Expect = 5e-14
 Identities = 49/158 (31%), Positives = 83/158 (52%), Gaps = 7/158 (4%)

Query: 3   SESELER--YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           SE++++   Y RQ+ + G E  ++L+ + V V G+ GLG  +A  +   GV  + L D+ 
Sbjct: 46  SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
             + ++L+ Q    EED+G+N   +S   +L + NS V +  + G L    +ED L G  
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQP-RLAELNSYVPVTAYTGPL----VEDFLSGFQ 160

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           V+V      E +  + ++ H  GI LV     GL+GQ+
Sbjct: 161 VVVLTNTPLEDQLRVGEFCHNRGIKLVVAGTRGLFGQL 198


>gb|AAB71466.1| (AC000098) Similar to Caenorhabditis unknown protein T03F1.1
           (gb|U88169). [Arabidopsis thaliana]
           Length = 445
           
 Score = 78.8 bits (191), Expect = 5e-14
 Identities = 50/166 (30%), Positives = 87/166 (52%), Gaps = 20/166 (12%)

Query: 19  VEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDL 78
           V+  E++++  VA+VG+GG+GS  A  LT  G+GR+LL D    EL+N+NR  L +  D 
Sbjct: 74  VDNYERIREFSVAIVGIGGVGSVAAEMLTRCGIGRLLLYDYDTVELANMNR--LFFRPDQ 131

Query: 79  GRNPKPLSAKWKLEKFNSDVKI-------------ETFVGKLTEENI---EDVLHGVDVI 122
               K  +A   L + N DV +             ETF   LT ++    ++   GVD++
Sbjct: 132 VGMTKTDAAVQTLAEINPDVVLESFTMNITTVQGFETFTSSLTNKSFCPSKEGGSGVDLV 191

Query: 123 VDCLDNFETRYLLDDYAHKVGIPLVHGAV--EGLYGQVTTIIPGKT 166
           + C+DN+E R  ++   +++    +   V  + + G +  ++PG+T
Sbjct: 192 LSCVDNYEARMAVNQACNELRQTWMESGVSEDAVSGHIQLLVPGET 237


>dbj|BAB10670.1| (AB025630) gene_id:MPA22.7~pir||T38013~similar to unknown protein
           [Arabidopsis thaliana]
           Length = 414
           
 Score = 78.8 bits (191), Expect = 5e-14
 Identities = 51/155 (32%), Positives = 77/155 (48%), Gaps = 2/155 (1%)

Query: 8   ERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNL 67
           E   R I  FG+E Q K+  + V V+G+GG+GS  A  L  +GVG++LL+D     LS+L
Sbjct: 31  EHLTRNIQFFGLESQHKVTGSYVVVIGLGGVGSHAASMLLRSGVGKLLLVDFDQVSLSSL 90

Query: 68  NRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHG-VDVIVDCL 126
           NR  +    D+G  PK +  K        +  IE  V      + E++L G  D ++DC+
Sbjct: 91  NRHAVATRADVG-IPKAMCLKKHFSSIFPECHIEAKVMLYDSSSEEEILSGKPDFVLDCI 149

Query: 127 DNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTI 161
           DN +T+  L     K G+ ++     G     T I
Sbjct: 150 DNIDTKVGLLAACVKRGLKVLSATGAGARADPTRI 184


>sp|Q29504|UBA1_RABIT UBIQUITIN-ACTIVATING ENZYME E1 >gi|1381183|gb|AAC48768.1| (U58653)
           ubiquitin-activating enzyme E1 [Oryctolagus cuniculus]
           Length = 1058
           
 Score = 78.4 bits (190), Expect = 7e-14
 Identities = 49/158 (31%), Positives = 83/158 (52%), Gaps = 7/158 (4%)

Query: 3   SESELER--YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           SE++++   Y RQ+ + G E  ++L+ + V V G+ GLG  +A  +   GV  + L D+ 
Sbjct: 46  SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
             + ++L+ Q    EED+G+N   +S   +L + NS V +  + G L    +ED L G  
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQP-RLAELNSYVPVTAYTGPL----VEDFLSGFQ 160

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           V+V      E +  + ++ H  GI LV     GL+GQ+
Sbjct: 161 VVVLTNSPLEDQLRVGEFCHSRGIKLVVADTRGLFGQL 198


>pir||A38564 ubiquitin--protein ligase (EC 6.3.2.19) E1 - human
           >gi|340072|gb|AAA61246.1| (M58028) ubiquitin-activating
           enzyme E1 [Homo sapiens]
           Length = 1058
           
 Score = 78.0 bits (189), Expect = 9e-14
 Identities = 49/158 (31%), Positives = 83/158 (52%), Gaps = 7/158 (4%)

Query: 3   SESELER--YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           SE++++   Y RQ+ + G E  ++L+ + V V G+ GLG  +A  +   GV  + L D+ 
Sbjct: 46  SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
             + ++L+ Q    EED+G+N   +S   +L + NS V +  + G L    +ED L G  
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQP-RLAELNSYVPVTAYTGPL----VEDFLSGFQ 160

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           V+V      E +  + ++ H  GI LV     GL+GQ+
Sbjct: 161 VVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQL 198


>gi|6320598 similar to ubiquitin activating enzyme (E1); Uba2p [Saccharomyces
           cerevisiae] >gi|1717852|sp|P52488|UBA2_YEAST
           UBIQUITIN-ACTIVATING ENZYME E1-LIKE
           (POLYMERASE-INTERACTING PROTEIN 2)
           >gi|1362482|pir||A57178 ubiquitin-activating enzyme
           homolog UBA2 - yeast  (Saccharomyces cerevisiae)
           >gi|793879|emb|CAA88617.1| (Z48725) Uba2 protein
           [Saccharomyces cerevisiae] >gi|927323|gb|AAB64832.1|
           (U32274) Uba2p; CAI: 0.15 [Saccharomyces cerevisiae]
           >gi|1835684|gb|AAB46626.1| (U17263) Pip2p [Saccharomyces
           cerevisiae]
           Length = 636
           
 Score = 76.1 bits (184), Expect = 3e-13
 Identities = 45/156 (28%), Positives = 82/156 (51%), Gaps = 4/156 (2%)

Query: 14  IMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILH 73
           + I G +  +KL+ ++  +VG GG+GS +   +     G I ++D    +LSNLNRQ L 
Sbjct: 8   VTIIGEDSYKKLRSSRCLLVGAGGIGSELLKDIILMEFGEIHIVDLDTIDLSNLNRQFLF 67

Query: 74  WEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDV--LHGVDVIVDCLDNFET 131
            ++D+ + PK  +A   ++ FN+  K+  + G + + +   +      D+I + LDN   
Sbjct: 68  RQKDI-KQPKSTTAVKAVQHFNNS-KLVPYQGNVMDISTFPLHWFEQFDIIFNALDNLAA 125

Query: 132 RYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
           R  ++  +  + +PL+     G  G +  IIPGKT+
Sbjct: 126 RRYVNKISQFLSLPLIESGTAGFDGYMQPIIPGKTE 161


>pir||T29201 hypothetical protein T03F1.1 - Caenorhabditis elegans
           >gi|1825606|gb|AAB42231.1| (U88169) similar to
           molybdoterin biosynthesis MOEB proteins [Caenorhabditis
           elegans]
           Length = 419
           
 Score = 76.1 bits (184), Expect = 3e-13
 Identities = 60/217 (27%), Positives = 101/217 (45%), Gaps = 30/217 (13%)

Query: 19  VEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDL 78
           V   E++++  VAVVGVGG+GS VA  LT  G+G+++L D    E++N+NR  L ++ + 
Sbjct: 76  VNEYERIREKTVAVVGVGGVGSVVAEMLTRCGIGKLILFDYDKVEIANMNR--LFYQPNQ 133

Query: 79  GRNPKPLSAKWKLEKFNSDVKIE-------------TFVGKLTEENIEDVLHGVDVIVDC 125
               K  +A+  L   N DV+IE             TFV ++ + ++ D    +D+++ C
Sbjct: 134 AGLSKVEAARDTLIHVNPDVQIEVHNFNITTMDNFDTFVNRIRKGSLTD--GKIDLVLSC 191

Query: 126 LDNFETRYLLDDYAHKVGIPLVHGAV--EGLYGQVTTIIPGKTKRLREIFPRIKKKG--- 180
           +DNFE R  ++   ++     +   V    + G +  I PGKT     + P +   G   
Sbjct: 192 VDNFEARMAVNMACNEENQIWMESGVSENAVSGHIQYIEPGKTACFACVPPLVVASGIDE 251

Query: 181 --------KFPILGATAGVIGSIQVTEVVKLITGYGE 209
                       L  T  V+    V   +K +  +GE
Sbjct: 252 RTLKRDGVCAASLPTTMAVVAGFLVMNTLKYLLNFGE 288


>emb|CAA40809.1| (X57583) mccB [Escherichia coli]
           Length = 350
           
 Score = 75.7 bits (183), Expect = 5e-13
 Identities = 62/235 (26%), Positives = 104/235 (43%), Gaps = 26/235 (11%)

Query: 3   SESELERYDRQIMIFGVEG------QEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILL 56
           + +E  RY R  + +   G      Q+KLK AKV ++G GG+G+ V+  L  +G+G I+L
Sbjct: 85  NSTENNRYSRNFLHYQSYGANPVLVQDKLKNAKVVILGCGGIGNHVSVILATSGIGEIIL 144

Query: 57  IDEQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVL 116
           ID    E +NL RQ+L  E+D+G+N K    K +L K NS++ +      + +      +
Sbjct: 145 IDNDQIENTNLTRQVLFSEDDVGKN-KTEVIKRELLKRNSEISVSEIALNINDYTDLHKV 203

Query: 117 HGVDVIVDCLDN-FETRYLLDDYAHKVGIPLVH-GAVEGLYGQVTTIIPGKT-------- 166
              D+ V   D+ F     ++ Y  +   P ++ G V  +       +PGKT        
Sbjct: 204 PEADIWVVSADHPFNLINWVNKYCVRANQPYINAGYVNDIAVFGPLYVPGKTGCYECQKV 263

Query: 167 ---------KRLREIFPRIKKKGKFPILGATAGVIGSIQVTEVVKLITGYGEPLA 212
                    + +      I  + K         V  ++   +V+K I  Y EPL+
Sbjct: 264 VADLYGSEKENIDHKIKLINSRFKPATFAPVNNVAAALCAADVIKFIGKYSEPLS 318


>gi|6678483 ubiquitin-activating enzyme E1, Chr X [Mus musculus]
           >gi|267190|sp|Q02053|UBA1_MOUSE UBIQUITIN-ACTIVATING
           ENZYME E1 1 >gi|111228|pir||JC1254 ubiquitin--protein
           ligase (EC 6.3.2.19) E1 - mouse
           >gi|220629|dbj|BAA01433.1| (D10576) ubiquitin activating
           enzyme E1 [Mus musculus]
           Length = 1058
           
 Score = 75.3 bits (182), Expect = 6e-13
 Identities = 48/158 (30%), Positives = 81/158 (50%), Gaps = 7/158 (4%)

Query: 3   SESELER--YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQ 60
           SE++++   Y RQ+ + G E  + L+ + V V G+ GLG  +A  +   GV  + L D+ 
Sbjct: 46  SEADIDESLYSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105

Query: 61  VPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD 120
             + ++L+ Q    EED+G+N   +S   +L + NS V +  + G L    +ED L    
Sbjct: 106 TTQWADLSSQFYLREEDIGKNRAEVSQP-RLAELNSYVPVTAYTGPL----VEDFLSSFQ 160

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           V+V      E +  + ++ H  GI LV     GL+GQ+
Sbjct: 161 VVVLTNSPLEAQLRVGEFCHSRGIKLVVADTRGLFGQL 198


 Score = 68.3 bits (164), Expect = 8e-11
 Identities = 48/167 (28%), Positives = 75/167 (44%), Gaps = 8/167 (4%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD Q+ +FG + QEKL K K  +VG G +G  +       G+     G +++ D    E
Sbjct: 450 RYDGQVAVFGSDFQEKLSKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEVVVTDMDTIE 509

Query: 64  LSNLNRQILH--WEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENI-EDVLHGVD 120
            SNLNRQ L   W+    ++    +A  ++  +      +  VG  TE    +D    +D
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPYIQVTSHQNRVGPDTERIYDDDFFQNLD 569

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            + + LDN + R  +D        PL+     G  G V  +IP  T+
Sbjct: 570 GVANALDNIDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTE 616


>dbj|BAA94076.1| (AB035495) ubiquitin-activating enzyme E1 [Carassius auratus]
           Length = 1058
           
 Score = 75.3 bits (182), Expect = 6e-13
 Identities = 46/149 (30%), Positives = 77/149 (50%), Gaps = 5/149 (3%)

Query: 10  YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNR 69
           Y RQ+ + G E  ++++ + V + G+ GLG  +A  +   GV  + L D+ V E  +L+ 
Sbjct: 55  YSRQLYVLGHEAMKRMQSSSVLISGLRGLGVEIAKNVILGGVKSVTLHDQGVAEWKDLSS 114

Query: 70  QILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLDNF 129
           Q    EEDLG+N   +S + +L + NS V + ++ G L  E     L    V+V    + 
Sbjct: 115 QFYLREEDLGKNRAEVS-QTRLAELNSYVPVTSYTGALNNE----FLTKFQVVVLTNSSL 169

Query: 130 ETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           + +  L D+ H  GI L+     GL+GQ+
Sbjct: 170 DEQIRLGDFCHSNGIKLIVADTRGLFGQL 198


 Score = 67.9 bits (163), Expect = 1e-10
 Identities = 53/167 (31%), Positives = 80/167 (47%), Gaps = 9/167 (5%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPV----AYYLTAAGVGRILLIDEQVPEL 64
           RYD QI +FG + QE L K +  +VG G +G  +    A    A+G G +++ D    E 
Sbjct: 451 RYDGQIAVFGSKLQELLAKQRYFLVGAGAIGCELLKNFAMMGLASGEGEVIVTDMDTIEK 510

Query: 65  SNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKI---ETFVGKLTEENI-EDVLHGVD 120
           SNLNRQ L    D+ +  K  +A   ++  N  V+I   +  VG  TE+   +D    +D
Sbjct: 511 SNLNRQFLFRPWDVTK-MKSETAAAAVKLMNPSVRITGHQNRVGPETEKVYDDDFFESLD 569

Query: 121 VIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            + + LDN + R  +D        PL+     G  G V  +IP  T+
Sbjct: 570 GVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTE 616


>gb|AAF25197.1|AF193553_1 (AF193553) ubiquitin-like protein activating enzyme [Drosophila
           melanogaster]
           Length = 700
           
 Score = 74.9 bits (181), Expect = 8e-13
 Identities = 55/163 (33%), Positives = 80/163 (48%), Gaps = 4/163 (2%)

Query: 22  QEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDLGRN 81
           QE +KK+KV VVG GG+G  V   L  +G   I +ID    +LSNLNRQ L   E +G++
Sbjct: 14  QELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKS 73

Query: 82  PKPLSAKWKLEKFNSDVKIETFVGKLTEENI-EDVLHGVDVIVDCLDNFETRYLLDDYAH 140
            K   A+     FN D KI  +   +T  +   +     D+++  LDN   R  ++    
Sbjct: 74  -KARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCL 132

Query: 141 KVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFP 183
              +PL+     G  GQV  I  G T +  E  P+ K++  FP
Sbjct: 133 NADVPLIESGTAGYNGQVELIKRGLT-QCYECTPKDKQR-SFP 173


>gb|AAF50484.2| (AE003556) Uba2 gene product [Drosophila melanogaster]
           Length = 700
           
 Score = 74.9 bits (181), Expect = 8e-13
 Identities = 55/163 (33%), Positives = 80/163 (48%), Gaps = 4/163 (2%)

Query: 22  QEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDLGRN 81
           QE +KK+KV VVG GG+G  V   L  +G   I +ID    +LSNLNRQ L   E +G++
Sbjct: 14  QELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKS 73

Query: 82  PKPLSAKWKLEKFNSDVKIETFVGKLTEENI-EDVLHGVDVIVDCLDNFETRYLLDDYAH 140
            K   A+     FN D KI  +   +T  +   +     D+++  LDN   R  ++    
Sbjct: 74  -KARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCL 132

Query: 141 KVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFP 183
              +PL+     G  GQV  I  G T +  E  P+ K++  FP
Sbjct: 133 NADVPLIESGTAGYNGQVELIKRGLT-QCYECTPKDKQR-SFP 173


>pir||C81307 probable molybdopterin biosynthesis protein Cj1046c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968482|emb|CAB73302.1| (AL139077) putative
           molybdopterin biosynthesis protein [Campylobacter
           jejuni]
           Length = 267
           
 Score = 74.5 bits (180), Expect = 1e-12
 Identities = 51/154 (33%), Positives = 85/154 (55%), Gaps = 9/154 (5%)

Query: 23  EKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDLGRNP 82
           +KLK  +VAV G+GGLGS +A  L  +GVG + LID  V E SNLNRQ  +   DLG+  
Sbjct: 80  DKLKNGRVAVCGLGGLGSHIAINLARSGVGYLKLIDFDVIEPSNLNRQ-AYRVSDLGKF- 137

Query: 83  KPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLDNFETRYLLDDYAH-- 140
           K  + K ++ + N  + +E    K+ E+N+E +   +D++ +  D+   + ++    H  
Sbjct: 138 KTEALKEQISEINPYISVEICTLKIDEDNLESLFKDIDIVCEAFDSAIAKAMIAQNFHRF 197

Query: 141 -KVGIPLVHGAVEGLYGQVTTIIPGKTKRLREIF 173
            K GI +    + G YG   +I   +T+++ + F
Sbjct: 198 YKDGILICASGLAG-YGDSNSI---QTRKIAKNF 227


>pir||I49380 ubiquitin-activating enzyme - mouse (fragment)
           >gi|558992|gb|AAA81009.1| (U15990) ubiquitin-activating
           enzyme [Mus musculus]
           Length = 179
           
 Score = 74.1 bits (179), Expect = 1e-12
 Identities = 46/149 (30%), Positives = 77/149 (50%), Gaps = 5/149 (3%)

Query: 10  YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNR 69
           Y RQ+ + G E  + L+ + V + G+ GLG  +A  +   GV  + L D+ + + ++L+ 
Sbjct: 14  YSRQLYVLGHEAMKHLQASSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGIAQWADLSS 73

Query: 70  QILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLDNF 129
           Q+   EED+G+N   +S   +L + NS V +  + G L    IE+ L G  V+V      
Sbjct: 74  QVCLREEDIGKNRAEISQP-RLAELNSYVPVFAYTGPL----IEEFLSGFQVVVLTNTPL 128

Query: 130 ETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           E +  + ++ H  GI LV     GL GQ+
Sbjct: 129 EYQLQVGEFCHSHGIKLVVADTRGLVGQL 157


>gb|AAD23691.1|AC006841_24 (AC006841) putative ubiquitin activating enzyme [Arabidopsis
           thaliana]
           Length = 700
           
 Score = 74.1 bits (179), Expect = 1e-12
 Identities = 47/147 (31%), Positives = 74/147 (49%), Gaps = 2/147 (1%)

Query: 22  QEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDLGRN 81
           Q  +K AKV +VG GG+G  +   L  +G   I +ID    E+SNLNRQ L     +G++
Sbjct: 7   QSAIKGAKVLMVGAGGIGCELLKTLALSGFEDIHIIDMDTIEVSNLNRQFLFRRSHVGQS 66

Query: 82  PKPLSAKWKLEKFNSDVKIETFVGKLTEENIE-DVLHGVDVIVDCLDNFETRYLLDDYAH 140
            K   A+  + +F  ++ I ++   +     + D     DV+++ LDN + R  ++    
Sbjct: 67  -KAKVARDAVLRFRPNINIRSYHANVKNPEFDVDFFKQFDVVLNGLDNLDARRHVNRLCL 125

Query: 141 KVGIPLVHGAVEGLYGQVTTIIPGKTK 167
              +PLV     G  GQVT  I GKT+
Sbjct: 126 AADVPLVESGTTGFLGQVTVHIKGKTE 152


>gb|AAF48050.1| (AE003486) CG1749 gene product [Drosophila melanogaster]
           Length = 404
           
 Score = 74.1 bits (179), Expect = 1e-12
 Identities = 62/216 (28%), Positives = 97/216 (44%), Gaps = 27/216 (12%)

Query: 19  VEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDL 78
           V+  E+++   VA+VGVGG+GS  A  LT  G+G+++L D    EL+N+NR  L +  D 
Sbjct: 65  VKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNR--LFFTPDQ 122

Query: 79  GRNPKPLSAKWKLEKFNSDVKIETFVGKLTE-ENIEDVL-----------HGVDVIVDCL 126
               K  +A   L   N DV+IET    +T  EN +  L             VD+++ C+
Sbjct: 123 AGLSKVAAAAATLSFINPDVEIETHNYNITTVENFDRFLDTISQGGRIAGQPVDLVLSCV 182

Query: 127 DNFETRYLLDDYAHKVGIPLVHGAV--EGLYGQVTTIIPGKTKRLREIFP---------- 174
           DNFE R  ++   ++  +      V    + G +  I PG T       P          
Sbjct: 183 DNFEARMAINAACNERNLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVAENIDEK 242

Query: 175 RIKKKGKFPI-LGATAGVIGSIQVTEVVKLITGYGE 209
            +K++G     L  T G+     V   +K +  +GE
Sbjct: 243 TLKREGVCAASLPTTMGITAGFLVQNALKYLLNFGE 278


>dbj|BAB04974.1| (AP001511) unknown conserved protein [Bacillus halodurans]
           Length = 259
           
 Score = 74.1 bits (179), Expect = 1e-12
 Identities = 47/145 (32%), Positives = 77/145 (52%), Gaps = 2/145 (1%)

Query: 4   ESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPE 63
           E  L ++ R  +  G +G E+LK++KVAV+GVGG+GS     L  +GVGRI+++D+   +
Sbjct: 5   EGMLHQFSRNELAIGHDGLERLKQSKVAVLGVGGVGSFSVEALARSGVGRIVIVDKDDVD 64

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVL-HGVDVI 122
           ++N+NRQI      +GR PK    K ++   N + ++       TEE  E    +  D +
Sbjct: 65  ITNVNRQIHALLSTVGR-PKVDLMKERISDINPECEVIALKMFYTEETYEQFFSYEPDYV 123

Query: 123 VDCLDNFETRYLLDDYAHKVGIPLV 147
           +D  D    +  L     K  IP++
Sbjct: 124 IDASDTITYKIHLMKECLKRNIPII 148


>pir||T00587 probable ubiquitin--protein ligase (EC 6.3.2.19) - Arabidopsis
           thaliana >gi|1750376|gb|AAB39246.1| (U80808) ubiquitin
           activating enzyme [Arabidopsis thaliana]
           >gi|3150409|gb|AAC16961.1| (AC004165) ubiquitin
           activating enzyme (UBA1) [Arabidopsis thaliana]
           Length = 1080
           
 Score = 73.7 bits (178), Expect = 2e-12
 Identities = 50/157 (31%), Positives = 82/157 (51%), Gaps = 7/157 (4%)

Query: 4   ESELERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPE 63
           E + + + RQ+ ++G E   +L  + V + G+ GLG+ +A  L  AGV  + L DE+V E
Sbjct: 72  EIDEDLHSRQLAVYGRETMRRLFASNVLISGMHGLGAEIAKNLILAGVKSVTLHDERVVE 131

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIV 123
           L +L+   +  E+D+G+N    S + KL+  N+ V + +    L +E+    L G  V+V
Sbjct: 132 LWDLSSNFVFSEDDVGKNRADASVQ-KLQDLNNAVVVSSLTKSLNKED----LSGFQVVV 186

Query: 124 DCLDNFETRYLLDDY--AHKVGIPLVHGAVEGLYGQV 158
               + E     DDY  +H+  I  V   V GL+G V
Sbjct: 187 FSDISMERAIEFDDYCHSHQPPIAFVKADVRGLFGSV 223


 Score = 71.8 bits (173), Expect = 7e-12
 Identities = 52/168 (30%), Positives = 81/168 (47%), Gaps = 10/168 (5%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD QI +FG + Q+KL+ AKV  VG G LG      L   GV     G++ + D+ + E
Sbjct: 474 RYDAQISVFGAKFQKKLEDAKVFTVGSGALGCEFLKNLALMGVSCGSQGKLTVTDDDIIE 533

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKL---EKFNSDVKIETFVGKLTEENIEDVL-HGV 119
            SNL+RQ L  + ++G+    ++A        +FN +  ++  VG  TE   +D     +
Sbjct: 534 KSNLSRQFLFRDWNIGQAKSTVAASAAAVINPRFNIEA-LQNRVGAETENVFDDAFWENL 592

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            V+V+ LDN   R  +D        PL+     G      ++IP  T+
Sbjct: 593 TVVVNALDNVNARLYVDSRCLYFQKPLLESGTLGTKCNTQSVIPHLTE 640


>pir||T20004 hypothetical protein C47E12.5 - Caenorhabditis elegans
           >gi|3875106|emb|CAA93101.1| (Z68882) predicted using
           Genefinder~Similarity to Mouse ubiquitin-activating
           enzyme (SW:UBA_MOUSE), contains similarity to Pfam
           domain: PF00899 (ThiF family), Score=374.3,
           E-value=4e-109, N=2; PF02134 (Repeat in
           ubiquitin-activating (UBA) proteins), Sc>
           Length = 1113
           
 Score = 73.7 bits (178), Expect = 2e-12
 Identities = 58/179 (32%), Positives = 84/179 (46%), Gaps = 14/179 (7%)

Query: 2   LSESELE----RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----G 52
           LSE++ +    RYD Q  +FG   QE L + +  VVG G +G  +   L+  GV     G
Sbjct: 488 LSETDCQPRQSRYDGQAAVFGWPYQECLFRQRWFVVGAGAIGCELLKNLSMMGVACGEGG 547

Query: 53  RILLIDEQVPELSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETF---VGKLTE 109
            I + D    E+SNLNRQ L    D+G      +A+  +  FNSDV+IE     VG  TE
Sbjct: 548 LIKITDMDQIEISNLNRQFLFRRRDVGGKKSECAAR-AVTAFNSDVRIEALAERVGLETE 606

Query: 110 ENIEDVLHG-VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
               D   G ++ + + LDN + R  +D       +PL+     G  G    + P  T+
Sbjct: 607 HIFNDEFFGELNGVANALDNVDARRYMDRRCVYYRLPLLESGTMGTKGNTQVVYPYLTE 665


>gb|AAD18053.1| (AF124162) molybdopterin synthase sulphurylase [Nicotiana
           plumbaginifolia]
           Length = 140
           
 Score = 73.4 bits (177), Expect = 2e-12
 Identities = 37/71 (52%), Positives = 47/71 (66%), Gaps = 2/71 (2%)

Query: 2   LSESELERYDRQIMI--FGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDE 59
           LS   + RY R +++  FGV+GQ  L K+ V V+G GGLGSP   YL A GVGRI ++D 
Sbjct: 70  LSPDMIYRYSRHLLLPSFGVQGQANLLKSSVLVIGAGGLGSPALLYLAACGVGRIGIVDH 129

Query: 60  QVPELSNLNRQ 70
            V EL+NL RQ
Sbjct: 130 DVVELNNLQRQ 140


>gi|6322639 ubiquitin activating enzyme, similar to Uba2p; Uba1p [Saccharomyces
           cerevisiae] >gi|549145|sp|P22515|UBA1_YEAST
           UBIQUITIN-ACTIVATING ENZYME E1 1 >gi|538616|pir||S38048
           ubiquitin--protein ligase (EC 6.3.2.19) - yeast
           (Saccharomyces cerevisiae) >gi|486375|emb|CAA82055.1|
           (Z28210) ORF YKL210w [Saccharomyces cerevisiae]
           Length = 1024
           
 Score = 73.0 bits (176), Expect = 3e-12
 Identities = 54/170 (31%), Positives = 82/170 (47%), Gaps = 12/170 (7%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGR-----ILLIDEQVPE 63
           RYD QI +FG++ Q+K+  +KV +VG G +G  +       G+G      I++ D    E
Sbjct: 416 RYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIE 475

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIE-----TFVGKLTEENIEDVL-H 117
            SNLNRQ L   +D+G+N   ++A+  +   N D+K +       VG  TEE   D    
Sbjct: 476 KSNLNRQFLFRPKDVGKNKSEVAAE-AVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWE 534

Query: 118 GVDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            +D + + LDN + R  +D        PL+     G  G    IIP  T+
Sbjct: 535 SLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTE 584


>gi|6755923 ubiquitin activating enzyme E1, Chr Y 1 [Mus musculus]
           >gi|5929777|gb|AAD56603.1| (AF127490) ubiquitin
           activating enzyme E1 [Mus musculus]
           Length = 1058
           
 Score = 73.0 bits (176), Expect = 3e-12
 Identities = 46/149 (30%), Positives = 76/149 (50%), Gaps = 5/149 (3%)

Query: 10  YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNR 69
           Y RQ+ + G E  + L+ + V + G+ GLG  +A  +   GV  + L D+ + + ++L+ 
Sbjct: 54  YSRQLYVLGHEAMKHLQASSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGIAQWADLSS 113

Query: 70  QILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLDNF 129
           Q    EED+G+N   +S   +L + NS V +  + G L    IE+ L G  V+V      
Sbjct: 114 QFCLREEDIGKNRAEISQP-RLAELNSYVPVFAYTGPL----IEEFLSGFQVVVLTNTPL 168

Query: 130 ETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           E +  + ++ H  GI LV     GL GQ+
Sbjct: 169 EYQLQVGEFCHSHGIKLVVADTRGLVGQL 197


>gb|AAF00149.1|AF150963_1 (AF150963) ubiquitin-activating enzyme E1 [Mus musculus]
           Length = 1058
           
 Score = 73.0 bits (176), Expect = 3e-12
 Identities = 46/149 (30%), Positives = 76/149 (50%), Gaps = 5/149 (3%)

Query: 10  YDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNR 69
           Y RQ+ + G E  + L+ + V + G+ GLG  +A  +   GV  + L D+ + + ++L+ 
Sbjct: 54  YSRQLYVLGHEAMKHLQASSVLISGLQGLGVEIAKNIILCGVKAVTLHDQGIAQWADLSS 113

Query: 70  QILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLDNF 129
           Q    EED+G+N   +S   +L + NS V +  + G L    IE+ L G  V+V      
Sbjct: 114 QFCLREEDIGKNRAEISQP-RLAELNSYVPVFAYTGPL----IEEFLSGFQVVVLTNTPL 168

Query: 130 ETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
           E +  + ++ H  GI LV     GL GQ+
Sbjct: 169 EYQLQVGEFCHSHGIKLVVADTRGLVGQL 197


>gb|AAF31704.1|AF218864_1 (AF218864) Smt3 activating enzyme 2 [Drosophila melanogaster]
           Length = 700
           
 Score = 73.0 bits (176), Expect = 3e-12
 Identities = 54/162 (33%), Positives = 80/162 (49%), Gaps = 4/162 (2%)

Query: 23  EKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDLGRNP 82
           E +KK+KV VVG GG+G  V   L  +G   I +ID    +LSNLNRQ L   E +G++ 
Sbjct: 15  ELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKS- 73

Query: 83  KPLSAKWKLEKFNSDVKIETFVGKLTEENI-EDVLHGVDVIVDCLDNFETRYLLDDYAHK 141
           K   A+     FN D KI  +   +T  +   +     D++++ LDN   R  ++     
Sbjct: 74  KARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLNALDNRADRNHVNRMCLN 133

Query: 142 VGIPLVHGAVEGLYGQVTTIIPGKTKRLREIFPRIKKKGKFP 183
             +PL+     G  GQV  I  G T +  E  P+ K++  FP
Sbjct: 134 ADVPLIESGTAGYNGQVELIKRGLT-QCYECTPKDKQR-SFP 173


>gb|AAG03059.1|AF288693_1 (AF288693) Ube1l [Mus musculus]
           Length = 775
           
 Score = 73.0 bits (176), Expect = 3e-12
 Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 5/151 (3%)

Query: 8   ERYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNL 67
           E Y RQ+ + G+   +++++AKV + G+ GLG+ VA  L   GVG + L D      ++L
Sbjct: 4   ELYSRQLYVLGLPAMQRIQEAKVLLCGLQGLGAEVAKNLVLTGVGSLTLHDPHPTCWADL 63

Query: 68  NRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVDVIVDCLD 127
             Q    EE LGRN +  +++ +L + N  V+I    G +T    ED+L G  V+V    
Sbjct: 64  AAQCFLSEESLGRN-RAEASQAQLAQLNEAVQISVHSGDIT----EDLLQGFQVVVLTDS 118

Query: 128 NFETRYLLDDYAHKVGIPLVHGAVEGLYGQV 158
             E +  +    HK G+  +     GL G++
Sbjct: 119 KLEDQLKVGPLCHKHGVRFLMAETRGLVGRL 149


>emb|CAA39056.1| (X55386) ubiquitin-activating enzyme [Saccharomyces cerevisiae]
           Length = 1024
           
 Score = 71.4 bits (172), Expect = 9e-12
 Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 12/170 (7%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGR-----ILLIDEQVPE 63
           RYD QI +FG++ Q+K+  +KV +VG G +G  +       G+G      I++ D    E
Sbjct: 416 RYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIE 475

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIE-----TFVGKLTEENIEDVL-H 117
            SNLNRQ L   +D+G+N   ++A+  +   N D+K +       VG  TE+   D    
Sbjct: 476 KSNLNRQFLFRPKDVGKNKSEVAAE-AVCAMNPDLKGKINAKIDKVGPETEKIFNDSFWE 534

Query: 118 GVDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            +D + + LDN + R  +D        PL+     G  G    IIP  T+
Sbjct: 535 SLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTE 584


>emb|CAB54319.2| (Z82062) contains similarity to Pfam domain: PF00899 (ThiF family),
           Score=156.7, E-value=1.3e-43, N=1; PF02134 (Repeat in
           ubiquitin-activating (UBA) proteins), Score=97.6,
           E-value=3.1e-26, N=1 [Caenorhabditis elegans]
           Length = 438
           
 Score = 71.4 bits (172), Expect = 9e-12
 Identities = 41/149 (27%), Positives = 77/149 (51%), Gaps = 2/149 (1%)

Query: 20  EGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDLG 79
           E  EK+ ++K+ V+G GG+G  +   L   G  ++ +ID    ++SNLNRQ L  +E + 
Sbjct: 6   EKHEKIVQSKILVIGAGGIGCELLKNLAVTGFRKVHVIDLDTIDISNLNRQFLFRKEHVS 65

Query: 80  RNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIE-DVLHGVDVIVDCLDNFETRYLLDDY 138
            + K  +A   +++F   +++      + E+    +     D++++ LDN   R  ++  
Sbjct: 66  -SSKAATATQVVKQFCPQIELTFDHDSIFEKKYNMEFFQAYDIVLNALDNRAARNYVNRM 124

Query: 139 AHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            H    PL+     G +GQV+ I+ GKT+
Sbjct: 125 CHAANRPLIDSGSGGYFGQVSVIMRGKTE 153


>pir||T51083 related to ubiquitin-activating enzyme homolog UBA2 [imported] -
           Neurospora crassa >gi|9368587|emb|CAB98247.1| (AL390092)
           related to ubiquitin-activating enzyme homolog UBA2
           [Neurospora crassa]
           Length = 641
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 47/146 (32%), Positives = 69/146 (47%), Gaps = 12/146 (8%)

Query: 27  KAKVAVVGVGGLGSPVAYYLTAAGVGRILLIDEQVPELSNLNRQILHWEEDLGRNPKPLS 86
           +A+V +VG GG+G  +   L   G G + ++D    +LSNLNRQ L   E + +  K L 
Sbjct: 28  QARVLMVGAGGIGCELLKNLVLTGFGEVHVVDLDTIDLSNLNRQFLFRHEHI-KKSKALV 86

Query: 87  AKWKLEKFNSDVKIETFVGKLTEENIEDVLHGVD------VIVDCLDNFETRYLLDDYAH 140
           AK   +KFN  VKI          NI+D    ++      ++ + LDN E R  ++    
Sbjct: 87  AKEAAQKFNPAVKIVAH-----HANIKDAQFNIEWFSSFRIVFNALDNLEARRHVNKMCL 141

Query: 141 KVGIPLVHGAVEGLYGQVTTIIPGKT 166
              +PL+     G  GQV  I  G T
Sbjct: 142 AADVPLIESGTTGFNGQVQVIKKGVT 167


>sp|P20973|UBA1_WHEAT UBIQUITIN-ACTIVATING ENZYME E1 1 >gi|100841|pir||A38373
           ubiquitin--protein ligase (EC 6.3.2.19) E1 - wheat
           >gi|285451|pir||A42873 ubiquitin-activating enzyme E1,
           UBA1 - Wheat >gi|170780|gb|AAA34308.1| (M55604)
           ubiquitin-activating enzyme E1 [Triticum aestivum]
           Length = 1051
           
 Score = 70.2 bits (169), Expect = 2e-11
 Identities = 52/169 (30%), Positives = 79/169 (45%), Gaps = 12/169 (7%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD QI +FG + Q KL++AK+ +VG G LG      L   G+     G + L D+ V E
Sbjct: 444 RYDAQISVFGSKLQNKLEEAKIFMVGSGALGCEFLKNLALMGISCSQNGNLTLTDDDVIE 503

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLH-----G 118
            SNL+RQ L  + ++G+ PK   A       N  + +E    + + E  E+V +      
Sbjct: 504 KSNLSRQFLFRDWNIGQ-PKSTVAATAAMVINPKLHVEALQNRASPET-ENVFNDAFWEN 561

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
           +D +V+ LDN   R  +D        PL+     G       +IP  T+
Sbjct: 562 LDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTE 610


>sp|P31252|UBA3_WHEAT UBIQUITIN-ACTIVATING ENZYME E1 3 >gi|7437981|pir||T06483 probable
           ubiquitin--protein ligase (EC 6.3.2.19) E1 - wheat
           >gi|170686|gb|AAA34266.1| (M90664) ubiquitin activating
           enzyme [Triticum aestivum]
           Length = 1053
           
 Score = 69.9 bits (168), Expect = 3e-11
 Identities = 49/169 (28%), Positives = 80/169 (46%), Gaps = 12/169 (7%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD Q+ +FG + Q+K+++A   VVG G LG      L   GV     G++ + D+ + E
Sbjct: 447 RYDAQVSVFGSKLQKKMEEANTFVVGSGALGCEFLKNLALMGVSCSSKGKLTITDDDIIE 506

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLH-----G 118
            SNL+RQ L  + ++G+  K   A       N  + I+    +   +  E+V H     G
Sbjct: 507 KSNLSRQFLFRDWNIGQ-AKSTVAATAASAINPSLHIDALQNRACPDT-ENVFHDTFWEG 564

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
           +DV+++ LDN   R  +D        PL+     G    +  +IP  T+
Sbjct: 565 LDVVINALDNVNARMYMDMRCLYFQKPLLESGTLGAKCNIQMVIPHLTE 613


>pir||A48195 ubiquitin--protein ligase E1 homolog - human
           Length = 1058
           
 Score = 68.7 bits (165), Expect = 6e-11
 Identities = 53/172 (30%), Positives = 81/172 (46%), Gaps = 12/172 (6%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGR-----ILLIDEQVPE 63
           RYD QI +FG   QEKL++    +VG G +G  +       G+G      + ++D    E
Sbjct: 460 RYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIE 519

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKL--TEENI--EDVLHGV 119
            SNL+RQ L   +D+GR PK   A       N D+++      L  T E+I  ++    V
Sbjct: 520 RSNLSRQFLFRSQDVGR-PKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 578

Query: 120 DVIVDCLDNFET-RYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLR 170
           D +   LD+F+  RY+     H +  PL+     G +G  T  +P  T+  R
Sbjct: 579 DGVAAALDSFQARRYVAARCTHYLK-PLLEAGTSGTWGSATVFMPHVTEAYR 629


>gi|4507767 ubiquitin-activating enzyme E1-like; Ubiquitin-activating enzyme-2;
           ubiquitin-activating enzyme E1, like [Homo sapiens]
           >gi|731039|sp|P41226|UBAL_HUMAN UBIQUITIN-ACTIVATING
           ENZYME E1 HOMOLOG (D8) >gi|986881|gb|AAA75388.1|
           (L13852) ubiquitin-activating enzyme E1-related protein
           [Homo sapiens]
           Length = 1011
           
 Score = 68.7 bits (165), Expect = 6e-11
 Identities = 53/172 (30%), Positives = 81/172 (46%), Gaps = 12/172 (6%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGVGR-----ILLIDEQVPE 63
           RYD QI +FG   QEKL++    +VG G +G  +       G+G      + ++D    E
Sbjct: 413 RYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIE 472

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKL--TEENI--EDVLHGV 119
            SNL+RQ L   +D+GR PK   A       N D+++      L  T E+I  ++    V
Sbjct: 473 RSNLSRQFLFRSQDVGR-PKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 531

Query: 120 DVIVDCLDNFET-RYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTKRLR 170
           D +   LD+F+  RY+     H +  PL+     G +G  T  +P  T+  R
Sbjct: 532 DGVAAALDSFQARRYVAARCTHYLK-PLLEAGTSGTWGSATVFMPHVTEAYR 582


>pir||T03964 probable ubiquitin--protein ligase (EC 6.3.2.19) - common tobacco
           >gi|1808656|emb|CAA71762.1| (Y10804) Ubiquitin
           activating enzyme E1 [Nicotiana tabacum]
           Length = 1080
           
 Score = 68.7 bits (165), Expect = 6e-11
 Identities = 51/168 (30%), Positives = 78/168 (46%), Gaps = 10/168 (5%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD QI +FG + Q+KL++AK  VVG G LG      L   GV     G++ + D+ V E
Sbjct: 474 RYDAQISVFGNKLQKKLEEAKAFVVGSGALGCEFLKNLALMGVCCGDKGKLTITDDDVIE 533

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKL---TEENIEDVL-HGV 119
            SNL+RQ L  + ++G+    ++A       N  + IE    +    TE   +D     +
Sbjct: 534 KSNLSRQFLFRDWNIGQAKSTVAAA-AASLINPRIHIEALQNRASPETESVFDDTFWENL 592

Query: 120 DVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
            V+++ LDN   R  +D        PL+     G       +IP  T+
Sbjct: 593 SVVINALDNVNARLYIDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTE 640


>sp|P31251|UBA2_WHEAT UBIQUITIN-ACTIVATING ENZYME E1 2 >gi|170684|gb|AAA34265.1| (M90663)
           ubiquitin activating enyme [Triticum aestivum]
           Length = 1051
           
 Score = 68.3 bits (164), Expect = 8e-11
 Identities = 51/169 (30%), Positives = 78/169 (45%), Gaps = 12/169 (7%)

Query: 9   RYDRQIMIFGVEGQEKLKKAKVAVVGVGGLGSPVAYYLTAAGV-----GRILLIDEQVPE 63
           RYD QI +FG   Q KL++AK+ +VG G LG      L   G+     G + + D+ V E
Sbjct: 444 RYDAQISVFGSTLQNKLEEAKIFMVGSGALGCEFLKNLALMGISCSQNGNLTVTDDDVIE 503

Query: 64  LSNLNRQILHWEEDLGRNPKPLSAKWKLEKFNSDVKIETFVGKLTEENIEDVLH-----G 118
            SNL+RQ L  + ++G+ PK   A       N  + +E    + + E  E+V +      
Sbjct: 504 KSNLSRQFLFRDWNIGQ-PKSTVAATAAMVINPKLHVEALQNRASPET-ENVFNDAFWEN 561

Query: 119 VDVIVDCLDNFETRYLLDDYAHKVGIPLVHGAVEGLYGQVTTIIPGKTK 167
           +D +V+ LDN   R  +D        PL+     G       +IP  T+
Sbjct: 562 LDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTE 610


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.142    0.403 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84603704
Number of Sequences: 2977
Number of extensions: 3650550
Number of successful extensions: 11397
Number of sequences better than 1.0e-10: 102
Number of HSP's better than  0.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 11133
Number of HSP's gapped (non-prelim): 135
length of query: 230
length of database: 189,106,746
effective HSP length: 54
effective length of query: 176
effective length of database: 156,788,448
effective search space: 27594766848
effective search space used: 27594766848
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 163 (67.9 bits)