BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2306 (flpa) DE:FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN (227 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75191 fibrillarin-like pre-rRNA processing protein PAB2306... 459 e-128 sp|O57811|FLPA_PYRHO FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEI... 448 e-125 pir||G72527 probable fibrillarin APE2196 - Aeropyrum pernix (str... 259 2e-68 sp|P35553|FLPA_METVO FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEI... 258 3e-68 sp|Q58108|FLPA_METJA FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEI... 252 2e-66 sp|P35552|FLPA_METVA FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEI... 252 3e-66 pdb|1FBN|A Chain A, Crystal Structure Of A Fibrillarin Homologue... 247 9e-65 gb|AAF69254.1| (AF201093) fibrillarin homolog [Sulfolobus acidoc... 241 5e-63 gb|AAK41216.1| Fibrillarin-like pre-rRNA processing protein [Sul... 234 6e-61 sp|O27283|FLPA_METTH FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEI... 221 5e-57 sp|Q22053|FBRL_CAEEL FIBRILLARIN >gi|7506840|pir||T24279 hypothe... 219 2e-56 gb|AAB62872.1| (AF007112) fibrillarin [Plasmodium falciparum] 216 2e-55 pir||T09555 fibrillarin - Arabidopsis thaliana >gi|4914455|emb|C... 214 8e-55 gb|AAG10103.1|AF233443_1 (AF233443) fibrillarin 1 [Arabidopsis t... 213 1e-54 sp|P22232|FBRL_XENLA FIBRILLARIN >gi|2134062|pir||I51417 fibrill... 212 3e-54 gb|AAF46950.1| (AE003459) Fib gene product [Drosophila melanogas... 210 1e-53 gb|AAF00542.1| (AF187871) fibrillarin homolog [Arabidopsis thali... 210 2e-53 gi|11425985 fibrillarin [Homo sapiens] >gi|105987|pir||A38712 fi... 209 3e-53 gi|4503661 fibrillarin [Homo sapiens] >gi|119853|sp|P22087|FBRL_... 209 3e-53 gb|AAC28913.1| (AC005393) FBRL_HUMAN; 34 KD NUCLEOLAR SCLERODERM... 209 3e-53 gi|6679755 fibrillarin [Mus musculus] >gi|544284|sp|P35550|FBRL_... 208 5e-53 emb|CAC18188.1| (AL451014) probable fibrillarin (NOP1) [Neurospo... 208 6e-53 gi|6320190 nucleolar protein, homologous to mammalian fibrillari... 207 1e-52 sp|Q27200|FBRL_TETTH FIBRILLARIN >gi|2654298|emb|CAA54924.1| (X7... 205 3e-52 gb|AAD13616.1| (AF110181) fibrillarin [Euglena gracilis] 205 5e-52 gb|AAC32120.1| (AF051216) probable fibrillarin [Picea mariana] 203 2e-51 sp|Q24957|FBRL_GIALA FIBRILLARIN >gi|11280294|pir||T47231 fibril... 201 6e-51 gb|AAF71690.1|AF168719_1 (AF168719) fibrillarin [Trypanosoma bru... 199 3e-50 sp|P35551|FBRL_SCHPO FIBRILLARIN >gi|422056|pir||S33690 fibrilla... 196 2e-49 sp|P35549|FBRL_LEIMA FIBRILLARIN >gi|425152|gb|AAA67420.1| (L262... 189 3e-47 sp|O53133|FLPA_METMA FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEI... 187 1e-46 dbj|BAB10546.1| (AB019226) fibrillarin-like [Arabidopsis thaliana] 184 9e-46 gi|11499669 fibrillarin (fib) [Archaeoglobus fulgidus] >gi|60160... 162 2e-39 emb|CAC12078.1| (AL445066) fibrillarin-like pre-rRNA processing ... 152 5e-36 emb|CAA98571.1| (Z74061) ORF YDL014w [Saccharomyces cerevisiae] 139 2e-32 gb|AAD15623.1| (AC006950) FBRL_HUMAN [AA 1- 227]; 34 KD NUCLEOLA... 138 4e-32 gb|AAG19552.1| (AE005045) fibrillarin; Fib [Halobacterium sp. NR... 127 1e-28 gb|AAF54870.1| (AE003697) CG10909 gene product [Drosophila melan... 121 6e-27 gb|AAG21982.1| (AF263383) SKP1 interacting partner 7 [Arabidopsi... 81 1e-14 >pir||H75191 fibrillarin-like pre-rRNA processing protein PAB2306 - Pyrococcus abyssi (strain Orsay) >gi|5457492|emb|CAB48983.1| (AJ248283) FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN [Pyrococcus abyssi] Length = 227 Score = 459 bits (1169), Expect = e-128 Identities = 227/227 (100%), Positives = 227/227 (100%) Query: 1 MVEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGA 60 MVEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGA Sbjct: 1 MVEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGA 60 Query: 61 AIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVED 120 AIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVED Sbjct: 61 AIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVED 120 Query: 121 RKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKS 180 RKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKS Sbjct: 121 RKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKS 180 Query: 181 RSIDVTKEPEQVFREVEKELSEYFEVIERLNLEPYEKDHALFVVRKT 227 RSIDVTKEPEQVFREVEKELSEYFEVIERLNLEPYEKDHALFVVRKT Sbjct: 181 RSIDVTKEPEQVFREVEKELSEYFEVIERLNLEPYEKDHALFVVRKT 227 >sp|O57811|FLPA_PYRHO FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN >gi|7450786|pir||A71224 probable fibrillarin-like pre-rRNA processing protein - Pyrococcus horikoshii >gi|3256437|dbj|BAA29120.1| (AP000001) 227aa long hypothetical fibrillarin-like pre-rRNA processing protein [Pyrococcus horikoshii] Length = 227 Score = 448 bits (1139), Expect = e-125 Identities = 218/227 (96%), Positives = 226/227 (99%) Query: 1 MVEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGA 60 MVEVKKHKFPGVY VIDDDGSE+IATKNLVPGQRVYGERVIKWEGEEYRIWNP+RSKLGA Sbjct: 1 MVEVKKHKFPGVYTVIDDDGSERIATKNLVPGQRVYGERVIKWEGEEYRIWNPNRSKLGA 60 Query: 61 AIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVED 120 AIMNGLKNFPIKPGKSVLYLGIASGTTASHVSD++GWEGKIFGIEFSPRVLRELVPIVE+ Sbjct: 61 AIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDIVGWEGKIFGIEFSPRVLRELVPIVEE 120 Query: 121 RKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKS 180 R+NIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLK+GGYGMIAVKS Sbjct: 121 RRNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKRGGYGMIAVKS 180 Query: 181 RSIDVTKEPEQVFREVEKELSEYFEVIERLNLEPYEKDHALFVVRKT 227 RSIDVTKEPEQVFREVE+ELSEYFEVIERLNLEPYEKDHALFVVRKT Sbjct: 181 RSIDVTKEPEQVFREVERELSEYFEVIERLNLEPYEKDHALFVVRKT 227 >pir||G72527 probable fibrillarin APE2196 - Aeropyrum pernix (strain K1) >gi|5105895|dbj|BAA81207.1| (AP000063) 233aa long hypothetical fibrillarin [Aeropyrum pernix] Length = 233 Score = 259 bits (655), Expect = 2e-68 Identities = 123/223 (55%), Positives = 175/223 (78%), Gaps = 2/223 (0%) Query: 1 MVEVKKH-KFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLG 59 +V V++H ++ GVY+V +DGS +IATKNLVPGQRVYGER+ ++ GEEYR WN +RSKL Sbjct: 4 VVSVREHDRWRGVYVVELEDGSLRIATKNLVPGQRVYGERIFRYNGEEYREWNAYRSKLA 63 Query: 60 AAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVE 119 AA++ GL P+K G +LYLGIASGTTASH+SD+IG G+I+G+EF+PRV+R+L+ +V Sbjct: 64 AALLKGLIELPVKEGDRILYLGIASGTTASHMSDIIGPRGRIYGVEFAPRVMRDLLTVVR 123 Query: 120 DRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVK 179 DR+NI PILGDA PE+YR LV VD ++ DVAQP QA I++ NA +L+ GGY ++A+K Sbjct: 124 DRRNIFPILGDARFPEKYRHLVEGVDGLYADVAQPEQAAIVVRNARFFLRDGGYMLMAIK 183 Query: 180 SRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHAL 221 +RSIDVT EP +V+ RE++ + E+ + ++L+P+++DHA+ Sbjct: 184 ARSIDVTTEPSEVYKREIKTLMDGGLEIKDVVHLDPFDRDHAM 226 >sp|P35553|FLPA_METVO FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN >gi|421710|pir||S34646 fibrillarin-like protein - Methanococcus voltae >gi|394800|emb|CAA52166.1| (X73988) pre-rRNA processing protein [Methanococcus voltae] Length = 228 Score = 258 bits (653), Expect = 3e-68 Identities = 123/220 (55%), Positives = 169/220 (75%), Gaps = 4/220 (1%) Query: 6 KHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGAAIMNG 65 K KF V+ + DG ++I TK+LVP +RVYGE+++ + EYR+WNP++SKLGA+I+NG Sbjct: 5 KEKFDNVFELDLGDGIKRIGTKSLVPNKRVYGEKLVNVKNTEYRVWNPNKSKLGASIING 64 Query: 66 LKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRKNIV 125 LK PIK G VLYLG ++GTT SHV+DV + ++ +EF+PR++RE + E RKN+ Sbjct: 65 LKEMPIKKGSKVLYLGASAGTTPSHVADVAE-DSPVYAVEFAPRIMREFIESCEGRKNLF 123 Query: 126 PILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDV 185 PILGDA KPEEY +V KVDVIFEDVAQP QA+ILI NA+ +LKKGGYGMI++K+RS+DV Sbjct: 124 PILGDANKPEEYANIVEKVDVIFEDVAQPNQAEILIKNAKWFLKKGGYGMISIKARSVDV 183 Query: 186 TKEPEQVFREVEKELSEY--FEVIERLNLEPYEKDHALFV 223 T+ P +F E +KE+ E F++++ +N+EP+EKDH LFV Sbjct: 184 TENPRVIF-EAQKEIMEQNGFKIVDAINIEPFEKDHMLFV 222 >sp|Q58108|FLPA_METJA FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN >gi|2127901|pir||A64387 fibrillarin-like pre-rRNA processing protein homolog - Methanococcus jannaschii >gi|1591412|gb|AAB98690.1| (U67516) fibrillarin (fib) [Methanococcus jannaschii] Length = 230 Score = 252 bits (638), Expect = 2e-66 Identities = 123/226 (54%), Positives = 177/226 (77%), Gaps = 5/226 (2%) Query: 1 MVEVK-KHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLG 59 M ++K K F +Y V DG ++IATK++V G++VY E++IK EEYRIWNP++SKL Sbjct: 1 MEDIKIKEIFENIYEVDLGDGLKRIATKSIVKGKKVYDEKIIKIGDEEYRIWNPNKSKLA 60 Query: 60 AAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVE 119 AAI+ GLK PIK +LYLG ++GTT SHV+D+ +G ++ IE++PR++REL+ Sbjct: 61 AAIIKGLKVMPIKRDSKILYLGASAGTTPSHVADIAD-KGIVYAIEYAPRIMRELLDACA 119 Query: 120 DRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVK 179 +R+NI+PILGDA KP+EY +V KVDVI+EDVAQP QA+ILI NA+ +LKKGGYGMIA+K Sbjct: 120 ERENIIPILGDANKPQEYANIVEKVDVIYEDVAQPNQAEILIKNAKWFLKKGGYGMIAIK 179 Query: 180 SRSIDVTKEPEQVFREVEKELSEY--FEVIERLNLEPYEKDHALFV 223 +RSIDVTK+P+++F+E +KE+ E F++++ +++EP+EKDH +FV Sbjct: 180 ARSIDVTKDPKEIFKE-QKEILEAGGFKIVDEVDIEPFEKDHVMFV 224 >sp|P35552|FLPA_METVA FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN >gi|421708|pir||S34645 fibrillarin-like protein - Methanococcus vannielii >gi|394798|emb|CAA52165.1| (X73987) pre-rRNA processing protein [Methanococcus vannielii] Length = 230 Score = 252 bits (636), Expect = 3e-66 Identities = 123/219 (56%), Positives = 167/219 (76%), Gaps = 2/219 (0%) Query: 6 KHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGAAIMNG 65 K F VY V DG ++IATK+L PG+RVYGE++I E +EYRIWNP++SKLGAAI+NG Sbjct: 7 KEIFSNVYGVDLGDGLKRIATKSLAPGKRVYGEKLIYSENKEYRIWNPNKSKLGAAIING 66 Query: 66 LKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRKNIV 125 LK PIK G VLYLG ++GTT SHVSD I + ++ +EF+PR++RE + +R N++ Sbjct: 67 LKKMPIKKGTKVLYLGASAGTTPSHVSD-ISEDTIVYAVEFAPRIMREFIDSCNERINLI 125 Query: 126 PILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDV 185 PILGDA +P EY +V KVDVIFEDVAQP QA+IL+ NA+ +L K GY MI++K+RSIDV Sbjct: 126 PILGDANRPFEYSNIVGKVDVIFEDVAQPNQAEILVKNAKWFLNKDGYAMISIKARSIDV 185 Query: 186 TKEPEQVFREVEKELSE-YFEVIERLNLEPYEKDHALFV 223 TK P+++F E +K L E F++++ +N+EP+EKDH +FV Sbjct: 186 TKNPKEIFLEQKKILIEGGFDIVDEINIEPFEKDHIMFV 224 >pdb|1FBN|A Chain A, Crystal Structure Of A Fibrillarin Homologue From Methanococcus Jannaschii, A Hyperthermophile, At 1.6 A Length = 230 Score = 247 bits (624), Expect = 9e-65 Identities = 120/220 (54%), Positives = 170/220 (76%), Gaps = 4/220 (1%) Query: 6 KHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGAAIMNG 65 K F +Y V DG ++IATK++V G++VY E++IK EEYRIWNP++SKL AAI+ G Sbjct: 7 KEIFENIYEVDLGDGLKRIATKSIVKGKKVYDEKIIKIGDEEYRIWNPNKSKLAAAIIKG 66 Query: 66 LKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRKNIV 125 LK PIK +LYLG ++GTT SHV+D+ +G ++ IE++PR+ REL+ +R+NI+ Sbjct: 67 LKVXPIKRDSKILYLGASAGTTPSHVADIAD-KGIVYAIEYAPRIXRELLDACAERENII 125 Query: 126 PILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDV 185 PILGDA KP+EY +V KVDVI+EDVAQP QA+ILI NA+ +LKKGGYG IA+K+RSIDV Sbjct: 126 PILGDANKPQEYANIVEKVDVIYEDVAQPNQAEILIKNAKWFLKKGGYGXIAIKARSIDV 185 Query: 186 TKEPEQVFREVEKELSEY--FEVIERLNLEPYEKDHALFV 223 TK+P+++F+E +KE+ E F++++ +++EP+EKDH FV Sbjct: 186 TKDPKEIFKE-QKEILEAGGFKIVDEVDIEPFEKDHVXFV 224 >gb|AAF69254.1| (AF201093) fibrillarin homolog [Sulfolobus acidocaldarius] Length = 231 Score = 241 bits (609), Expect = 5e-63 Identities = 115/224 (51%), Positives = 161/224 (71%), Gaps = 1/224 (0%) Query: 3 EVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGAAI 62 +V K +F VY I +DG+ ++ TKNL PG VYGER+IK+ G EYR WN RSKL AI Sbjct: 6 KVTKTQFDNVYECIFNDGTTRLCTKNLSPGHNVYGERLIKYGGVEYREWNAFRSKLAGAI 65 Query: 63 MNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRK 122 + GLK PI G +LYLG ASGTT SH+SD++ +GK++ +EFSPRV+REL+ + + R Sbjct: 66 VKGLKYNPIVKGSKILYLGAASGTTPSHISDIVELQGKVYSVEFSPRVIRELLLVAQYRP 125 Query: 123 NIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRS 182 N+ PIL DA P+ Y++LV VD+++ D+AQP + +I + NA +LKK GY MIA+KSRS Sbjct: 126 NMFPILADARFPQYYKSLVENVDIVYVDIAQPNETEIAMYNARFFLKKNGYMMIAIKSRS 185 Query: 183 IDVTKEPEQVFREVEKELSEY-FEVIERLNLEPYEKDHALFVVR 225 IDVTK+P +++ K+L + F++ E L L+PY+KDHA+ VV+ Sbjct: 186 IDVTKDPREIYNAEAKKLEDAGFDIREVLELDPYDKDHAMIVVK 229 >gb|AAK41216.1| Fibrillarin-like pre-rRNA processing protein [Sulfolobus solfataricus] Length = 232 Score = 234 bits (591), Expect = 6e-61 Identities = 114/222 (51%), Positives = 159/222 (71%), Gaps = 1/222 (0%) Query: 1 MVEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGA 60 ++ VK+ +Y +DGS ++ T+NLVP VYGER+IK+EG EYR WN RSKL Sbjct: 4 VITVKQTNMENIYECEFNDGSFRLCTRNLVPNFNVYGERLIKYEGVEYREWNAFRSKLAG 63 Query: 61 AIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVED 120 AI+ GLK PI+ G VLYLG ASGTT SHVSD+I GK +G+EFSPRV+REL+ + + Sbjct: 64 AILKGLKTNPIRKGTKVLYLGAASGTTISHVSDIIELNGKAYGVEFSPRVVRELLLVAQR 123 Query: 121 RKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKS 180 R NI P+L DA P+ Y+++V VDV++ D+AQP Q I I NA+ +LK G ++ +K+ Sbjct: 124 RPNIFPLLADARFPQSYKSVVENVDVLYVDIAQPDQTDIAIYNAKFFLKVNGDMLLVIKA 183 Query: 181 RSIDVTKEPEQVFR-EVEKELSEYFEVIERLNLEPYEKDHAL 221 RSIDVTK+P+++++ EVEK + FE I+ +NL+PY+KDHA+ Sbjct: 184 RSIDVTKDPKEIYKTEVEKLENSNFETIQIINLDPYDKDHAI 225 >sp|O27283|FLPA_METTH FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN >gi|7450787|pir||C69029 fibrillarin-like pre-rRNA processing protein - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622325|gb|AAB85704.1| (AE000889) fibrillarin-like pre-rRNA processing protein [Methanobacterium thermoautotrophicum] Length = 224 Score = 221 bits (558), Expect = 5e-57 Identities = 108/228 (47%), Positives = 160/228 (69%), Gaps = 8/228 (3%) Query: 1 MVEVKKHK-FPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLG 59 M VK+ K GV+I+ + + T N PG +VYGER+I W G EYR+W+P RSKL Sbjct: 1 MYAVKEVKGMDGVFIM-----NNSLLTINPNPGVKVYGERIIDWGGREYRVWDPRRSKLA 55 Query: 60 AAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVE 119 AAI+NGL+ F + VLYLG ++GTTASH+SD++ +G+++ IEFSPR++REL+ + E Sbjct: 56 AAILNGLRGFSLNSDSRVLYLGASAGTTASHISDIVT-DGRVYCIEFSPRMMRELLGVCE 114 Query: 120 DRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVK 179 RKN+ P+L DA++P Y +V D+++ DVAQP Q ++ I+N + +LK+ GYG+I +K Sbjct: 115 SRKNMAPLLEDASRPLSYLRMVEAADLVYCDVAQPDQTRLFIENMDCFLKRDGYGLIMIK 174 Query: 180 SRSIDVTKEPEQVFR-EVEKELSEYFEVIERLNLEPYEKDHALFVVRK 226 +RSIDVT+ P ++FR EV K S F +I+++ L PYEKDH +V++ Sbjct: 175 ARSIDVTRSPRKIFREEVGKLESSGFRIIDQVGLNPYEKDHMAVLVKR 222 >sp|Q22053|FBRL_CAEEL FIBRILLARIN >gi|7506840|pir||T24279 hypothetical protein T01C3.7 - Caenorhabditis elegans >gi|3879244|emb|CAB01657.1| (Z78413) predicted using Genefinder~Similarity to Xenopus fibrillarin protein (SW:FBRL_XENLA), contains similarity to Pfam domain: PF01269 (Fibrillarin), Score=608.3, E-value=1.4e-179, N=1~cDNA EST yk51g11.5 comes from this gene; cDNA EST EMBL:M89444 c> Length = 352 Score = 219 bits (552), Expect = 2e-56 Identities = 115/227 (50%), Positives = 157/227 (68%), Gaps = 7/227 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE----EYRIWNPHRSK 57 V V+ H+ GV+IV + + +ATKN+V G+ VYGE+ + + EYR+WNP RSK Sbjct: 117 VVVEPHRLGGVFIVKGKE--DALATKNMVVGESVYGEKRVSVDDGAGSIEYRVWNPFRSK 174 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 L A+IM GL+N IKPG +LYLG ASGTT SH SDV+G EG ++ +EFS R R+L+ + Sbjct: 175 LAASIMGGLENTHIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLGV 234 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R N+VPI+ DA P +YR LV VDVIF DVAQP QA+I+ NA+ +L+ GG+ +I+ Sbjct: 235 AKKRPNVVPIVEDARHPHKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGGHAVIS 294 Query: 178 VKSRSIDVTKEPEQVFR-EVEKELSEYFEVIERLNLEPYEKDHALFV 223 +K+ ID T EPE VF EV K E F+ +E++ LEPYE+DHA+ V Sbjct: 295 IKANCIDSTAEPEAVFAGEVNKLKEEKFKPLEQVTLEPYERDHAVVV 341 >gb|AAB62872.1| (AF007112) fibrillarin [Plasmodium falciparum] Length = 301 Score = 216 bits (544), Expect = 2e-55 Identities = 112/225 (49%), Positives = 156/225 (68%), Gaps = 7/225 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGER----VIKWEGEEYRIWNPHRSK 57 V V H+FPGVY++ S+ + TKNLVPG+ VYGE+ + + E EYR+WNP RSK Sbjct: 73 VIVVPHRFPGVYLL--KGKSDILVTKNLVPGESVYGEKRYEVMTEDEKIEYRVWNPFRSK 130 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 LGA +M G+ N PI+PG VLYLG A+GT+ SHVSD++G EG ++ +EFS R R+L + Sbjct: 131 LGACLMGGVGNMPIRPGSKVLYLGAANGTSVSHVSDMVGDEGVVYAVEFSHRSGRDLTNM 190 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R NIVPI+ DA +P +YR LV VDV+F DVAQP QA+I+ NA ++LK GG+ +I+ Sbjct: 191 SKKRSNIVPIVEDARQPTKYRMLVDMVDVVFADVAQPDQARIVAMNAHMFLKTGGWFIIS 250 Query: 178 VKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHAL 221 +K+ +D T +PE VF E+EK E + E+L LEP+ + HA+ Sbjct: 251 IKANCVDSTAKPEVVFASEMEKLKKENCKPKEKLTLEPFHRHHAI 295 >pir||T09555 fibrillarin - Arabidopsis thaliana >gi|4914455|emb|CAB43694.1| (AL050400) fibrillarin-like protein [Arabidopsis thaliana] >gi|7269413|emb|CAB81373.1| (AL161563) fibrillarin-like protein [Arabidopsis thaliana] >gi|9965655|gb|AAG10104.1|AF233444_1 (AF233444) fibrillarin 2 [Arabidopsis thaliana] >gi|9965796|gb|AAG10153.1| (AF267171) fibrillarin 2 [Arabidopsis thaliana] Length = 320 Score = 214 bits (539), Expect = 8e-55 Identities = 115/228 (50%), Positives = 153/228 (66%), Gaps = 8/228 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----EYRIWNPHRS 56 V V+ H+ GV+I + + + TKNLVPG+ VY E+ I + E EYR+WNP RS Sbjct: 80 VIVEPHRHAGVFIAKGKE--DALVTKNLVPGEAVYNEKRISVQNEDGTKTEYRVWNPFRS 137 Query: 57 KLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVP 116 KL AAI+ G+ N IKPG VLYLG ASGTT SHVSD++G EG ++ +EFS R R+LV Sbjct: 138 KLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVN 197 Query: 117 IVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMI 176 + + R N++PI+ DA P +YR LV VDVIF DVAQP QA+IL NA +LK GG+ +I Sbjct: 198 MAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKSGGHFVI 257 Query: 177 AVKSRSIDVTKEPEQVFR-EVEKELSEYFEVIERLNLEPYEKDHALFV 223 ++K+ ID T E VF+ EV+K E F+ E++ LEP+E+DHA V Sbjct: 258 SIKANCIDSTVPAEAVFQTEVKKLQQEQFKPAEQVTLEPFERDHACVV 305 >gb|AAG10103.1|AF233443_1 (AF233443) fibrillarin 1 [Arabidopsis thaliana] >gi|9965751|gb|AAG10152.1| (AF265547) fibrillarin 1 [Arabidopsis thaliana] >gi|10177413|dbj|BAB10544.1| (AB019226) fibrillarin-like [Arabidopsis thaliana] Length = 308 Score = 213 bits (538), Expect = 1e-54 Identities = 115/228 (50%), Positives = 153/228 (66%), Gaps = 8/228 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----EYRIWNPHRS 56 V V+ H+ GV+I + + + TKNLVPG+ VY E+ I + E EYR+WNP RS Sbjct: 69 VIVEPHRHAGVFIAKGKE--DALVTKNLVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRS 126 Query: 57 KLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVP 116 KL AAI+ G+ N IKPG VLYLG ASGTT SHVSD++G EG ++ +EFS R R+LV Sbjct: 127 KLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVN 186 Query: 117 IVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMI 176 + + R N++PI+ DA P +YR LV VDVIF DVAQP QA+IL NA +LK GG+ +I Sbjct: 187 MAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASFFLKTGGHFVI 246 Query: 177 AVKSRSIDVTKEPEQVFR-EVEKELSEYFEVIERLNLEPYEKDHALFV 223 ++K+ ID T E VF+ EV+K E F+ E++ LEP+E+DHA V Sbjct: 247 SIKANCIDSTVAAEAVFQSEVKKLQQEQFKPAEQVTLEPFERDHACVV 294 >sp|P22232|FBRL_XENLA FIBRILLARIN >gi|2134062|pir||I51417 fibrillarin - African clawed frog >gi|214144|gb|AAA49710.1| (M28874) fibrillarin [Xenopus laevis] Length = 323 Score = 212 bits (534), Expect = 3e-54 Identities = 114/227 (50%), Positives = 152/227 (66%), Gaps = 7/227 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWE-GE---EYRIWNPHRSK 57 V V+ H+ G++I + + + TKNLVPG+ VYGE+ I E GE EYR WNP RSK Sbjct: 88 VIVEPHRHEGIFICRGKE--DALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSK 145 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 + AAI+ G+ IKPG VLYLG ASGTT SHVSDV+G EG ++ +EFS R R+L+ + Sbjct: 146 IAAAILGGVDQIHIKPGVKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINV 205 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R NI+P++ DA P +YR LV VDV+F DVAQP Q +I+ NA +LK GG+ +I+ Sbjct: 206 AKKRTNIIPVIEDARHPHKYRILVGMVDVVFADVAQPDQTRIVALNAHNFLKNGGHFVIS 265 Query: 178 VKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 +K+ ID T PE VF EV+K E + E+L LEPYE+DHA+ V Sbjct: 266 IKANCIDSTAAPEAVFAAEVKKMQQENMKPQEQLTLEPYERDHAVVV 312 >gb|AAF46950.1| (AE003459) Fib gene product [Drosophila melanogaster] Length = 344 Score = 210 bits (529), Expect = 1e-53 Identities = 110/227 (48%), Positives = 153/227 (66%), Gaps = 7/227 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWE--GE--EYRIWNPHRSK 57 V ++ H+ GV+I + + + T+N VPG VYGE+ I E GE EYR+WNP RSK Sbjct: 111 VTIEPHRHEGVFIARGKE--DALVTRNFVPGSEVYGEKRISVETNGEKIEYRVWNPFRSK 168 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 L AA++ G++ + PG VLYLG ASGTT SHVSDV+G EG ++ +EFS R R+L+ + Sbjct: 169 LAAAVLGGVEQIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINV 228 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R NI+PI+ DA P +YR LV VD IF DVAQP Q +I+ NA+ +LK GG+ +I+ Sbjct: 229 AKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVIS 288 Query: 178 VKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 +K+ ID T +PE VF EV+K ++ + E+L LEPYE+DHA+ V Sbjct: 289 IKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVV 335 >gb|AAF00542.1| (AF187871) fibrillarin homolog [Arabidopsis thaliana] Length = 310 Score = 210 bits (528), Expect = 2e-53 Identities = 116/230 (50%), Positives = 153/230 (66%), Gaps = 10/230 (4%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----EYRIWNPHRS 56 V V+ H+ GV+I + + + TKNLVPG+ VY E+ I + E EYR+WNP RS Sbjct: 69 VIVEPHRHAGVFIAKGKE--DALVTKNLVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRS 126 Query: 57 KLGAAIMNG--LKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLREL 114 KL AAI+ G L N IKPG VLYLG ASGTT SHVSD++G EG ++ +EFS R R+L Sbjct: 127 KLAAAILGGVDLDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDL 186 Query: 115 VPIVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYG 174 V + + R N++PI+ DA P +YR LV VDVIF DVAQP QA+IL NA +LK GG+ Sbjct: 187 VNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASFFLKTGGHF 246 Query: 175 MIAVKSRSIDVTKEPEQVFR-EVEKELSEYFEVIERLNLEPYEKDHALFV 223 +I++K+ ID T E VF+ EV+K E F+ E++ LEP+E+DHA V Sbjct: 247 VISIKANCIDSTVAAEAVFQSEVKKLQQEQFKPAEQVTLEPFERDHACVV 296 >gi|11425985 fibrillarin [Homo sapiens] >gi|105987|pir||A38712 fibrillarin [validated] - human >gi|31395|emb|CAA39935.1| (X56597) fibrillarin [Homo sapiens] Length = 321 Score = 209 bits (526), Expect = 3e-53 Identities = 112/227 (49%), Positives = 151/227 (66%), Gaps = 7/227 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGE-RVIKWEGE---EYRIWNPHRSK 57 V V+ H+ GV+I + + + TKNLVPG+ VYGE RV EG+ EYR WNP RSK Sbjct: 86 VMVEPHRHEGVFICRGKE--DALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSK 143 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 L AAI+ G+ IKPG VLYLG ASGTT SHVSD++G +G ++ +EFS R R+L+ + Sbjct: 144 LAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINL 203 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R NI+P++ DA P +YR L+ VDVIF DVAQP Q +I+ NA +L+ GG+ +I+ Sbjct: 204 AKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVIS 263 Query: 178 VKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 +K+ ID T E VF EV+K E + E+L LEPYE+DHA+ V Sbjct: 264 IKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVV 310 >gi|4503661 fibrillarin [Homo sapiens] >gi|119853|sp|P22087|FBRL_HUMAN FIBRILLARIN (34 KD NUCLEOLAR SCLERODERMA ANTIGEN) >gi|182592|gb|AAA52453.1| (M59849) fibrillarin [Homo sapiens] Length = 321 Score = 209 bits (526), Expect = 3e-53 Identities = 112/227 (49%), Positives = 151/227 (66%), Gaps = 7/227 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGE-RVIKWEGE---EYRIWNPHRSK 57 V V+ H+ GV+I + + + TKNLVPG+ VYGE RV EG+ EYR WNP RSK Sbjct: 86 VMVEPHRHEGVFICRGKE--DALVTKNLVPGESVYGEKRVSISEGDDKFEYRAWNPFRSK 143 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 L AAI+ G+ IKPG VLYLG ASGTT SHVSD++G +G ++ +EFS R R+L+ + Sbjct: 144 LAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINL 203 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R NI+P++ DA P +YR L+ VDVIF DVAQP Q +I+ NA +L+ GG+ +I+ Sbjct: 204 AKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVIS 263 Query: 178 VKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 +K+ ID T E VF EV+K E + E+L LEPYE+DHA+ V Sbjct: 264 IKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVV 310 >gb|AAC28913.1| (AC005393) FBRL_HUMAN; 34 KD NUCLEOLAR SCLERODERMA ANTIGEN [Homo sapiens] Length = 318 Score = 209 bits (526), Expect = 3e-53 Identities = 112/227 (49%), Positives = 151/227 (66%), Gaps = 7/227 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGE-RVIKWEGE---EYRIWNPHRSK 57 V V+ H+ GV+I + + + TKNLVPG+ VYGE RV EG+ EYR WNP RSK Sbjct: 83 VMVEPHRHEGVFICRGKE--DALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSK 140 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 L AAI+ G+ IKPG VLYLG ASGTT SHVSD++G +G ++ +EFS R R+L+ + Sbjct: 141 LAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINL 200 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R NI+P++ DA P +YR L+ VDVIF DVAQP Q +I+ NA +L+ GG+ +I+ Sbjct: 201 AKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVIS 260 Query: 178 VKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 +K+ ID T E VF EV+K E + E+L LEPYE+DHA+ V Sbjct: 261 IKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVV 307 >gi|6679755 fibrillarin [Mus musculus] >gi|544284|sp|P35550|FBRL_MOUSE FIBRILLARIN (NUCLEOLAR PROTEIN 1) >gi|481220|pir||S38342 fibrillarin - mouse >gi|296548|emb|CAA80307.1| (Z22593) fibrillarin [Mus musculus] Length = 327 Score = 208 bits (524), Expect = 5e-53 Identities = 112/227 (49%), Positives = 151/227 (66%), Gaps = 7/227 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGE-RVIKWEGE---EYRIWNPHRSK 57 V V+ H+ GV+I + + + TKNLVPG+ VYGE RV EG+ EYR WNP RSK Sbjct: 92 VMVEPHRHEGVFICRGKE--DALFTKNLVPGESVYGEKRVSISEGDDTIEYRAWNPFRSK 149 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 L AAI+ G+ IKPG VLYLG ASGTT SHVSD++G +G ++ +EFS R R+L+ + Sbjct: 150 LAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINL 209 Query: 118 VEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIA 177 + R NI+P++ DA P +YR L+ VDVIF DVAQP Q +I+ NA +L+ GG+ +I+ Sbjct: 210 AKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVIS 269 Query: 178 VKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 +K+ ID T E VF EV+K E + E+L LEPYE+DHA+ V Sbjct: 270 IKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVV 316 >emb|CAC18188.1| (AL451014) probable fibrillarin (NOP1) [Neurospora crassa] Length = 342 Score = 208 bits (523), Expect = 6e-53 Identities = 112/232 (48%), Positives = 152/232 (65%), Gaps = 13/232 (5%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----------EYRI 50 V V+ H+ GV++ + +AT NLVPG+ VYGE+ I E EYRI Sbjct: 99 VIVEPHRHKGVFVARGGK-EDLLATVNLVPGESVYGEKRISVENASKEEGGASTKTEYRI 157 Query: 51 WNPHRSKLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRV 110 WNP RSKL A I+ GL+ +KPG VLYLG ASGT+ SHV+D++G G ++ +EFS R Sbjct: 158 WNPFRSKLAAGILGGLETIYMKPGSKVLYLGAASGTSVSHVADIVGPTGSVYAVEFSHRS 217 Query: 111 LRELVPIVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKK 170 R+L+ + R N++PI+ DA KP YR L+P VDVIF DVAQP QA+I+ NA+++LK+ Sbjct: 218 GRDLINMATRRTNVIPIVEDARKPMAYRMLLPMVDVIFADVAQPDQARIVGINAKLFLKQ 277 Query: 171 GGYGMIAVKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHAL 221 GG +I++K+ ID T PEQVF EV+K + F E+L LEPYE+DHA+ Sbjct: 278 GGGLLISIKASCIDSTAPPEQVFASEVQKLREDKFFPKEQLTLEPYERDHAM 329 >gi|6320190 nucleolar protein, homologous to mammalian fibrillarin; Nop1p [Saccharomyces cerevisiae] >gi|119857|sp|P15646|FBRL_YEAST FIBRILLARIN (NUCLEOLAR PROTEIN 1) >gi|101461|pir||S25421 nucleolar protein NOP1 - yeast (Saccharomyces cerevisiae) >gi|172048|gb|AAA34816.1| (J05230) fibrillarin [Saccharomyces cerevisiae] >gi|683683|emb|CAA88345.1| (Z48432) nucleolar protein NOP1 (J05230) [Saccharomyces cerevisiae] >gi|1430979|emb|CAA98572.1| (Z74062) ORF YDL014w [Saccharomyces cerevisiae] Length = 327 Score = 207 bits (521), Expect = 1e-52 Identities = 111/236 (47%), Positives = 151/236 (63%), Gaps = 14/236 (5%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----------EYRI 50 V ++ H+ GVYI + + + TKN+ PG+ VYGE+ I E EYR+ Sbjct: 86 VVIEPHRHAGVYIARGKE--DLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRV 143 Query: 51 WNPHRSKLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRV 110 WNP RSKL A IM GL I PGK VLYLG ASGT+ SHVSDV+G EG ++ +EFS R Sbjct: 144 WNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRP 203 Query: 111 LRELVPIVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKK 170 REL+ + + R NI+PI+ DA P++YR L+ VD +F DVAQP QA+I+ N+ ++LK Sbjct: 204 GRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKD 263 Query: 171 GGYGMIAVKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFVVR 225 G +I++K+ ID T + E VF REV+K E + +E+L LEPYE+DH + V R Sbjct: 264 QGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGR 319 >sp|Q27200|FBRL_TETTH FIBRILLARIN >gi|2654298|emb|CAA54924.1| (X77962) fibrillarin [Tetrahymena thermophila] Length = 294 Score = 205 bits (517), Expect = 3e-52 Identities = 110/223 (49%), Positives = 149/223 (66%), Gaps = 7/223 (3%) Query: 4 VKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWE--GE--EYRIWNPHRSKLG 59 + KH+ GV+I E + TKN PG+ VY E+ + E GE EYR+WNP+RSK+ Sbjct: 67 IVKHRLEGVFICKGQ--LEALVTKNFFPGESVYNEKRMSVEENGEKIEYRVWNPYRSKIA 124 Query: 60 AAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVE 119 AA++ G+ + IKPG VLYLG ASGTT SHV+D++G G ++ +EFS R R+LV + + Sbjct: 125 AAVVGGISDIHIKPGSKVLYLGGASGTTVSHVADIVGPTGVVYAVEFSHRSGRDLVNMAK 184 Query: 120 DRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVK 179 R N+VPI+GDA KP+EYR LV VDV+F DVAQP QA+I+ N +LK GG+ +I++K Sbjct: 185 KRTNVVPIIGDARKPQEYRFLVGMVDVVFADVAQPDQARIMGMNCLYFLKNGGHFLISIK 244 Query: 180 SRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHAL 221 + ID T EP VF EV+K E + L LEPYE+DHA+ Sbjct: 245 ACCIDSTNEPAVVFAAEVQKLKEEGLKPELLLTLEPYERDHAM 287 >gb|AAD13616.1| (AF110181) fibrillarin [Euglena gracilis] Length = 281 Score = 205 bits (515), Expect = 5e-52 Identities = 112/232 (48%), Positives = 148/232 (63%), Gaps = 10/232 (4%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEG---------EEYRIWN 52 V V+ HK V + +AT NLVPG VYGE+ ++ E +EYR+WN Sbjct: 40 VVVEPHKVHAGIFVSRGKSEDSLATLNLVPGVSVYGEKRVQTETTDANGAPEKKEYRVWN 99 Query: 53 PHRSKLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLR 112 P+RSKL AA++ G+ N + PG VLYLG ASGTT SHVSD++G G ++ +EFS R R Sbjct: 100 PYRSKLAAAVVGGIDNCKVAPGAKVLYLGAASGTTVSHVSDIVGPTGIVYAVEFSHRSGR 159 Query: 113 ELVPIVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGG 172 +LV + + R NIVPI+ DA P+ YR LV VD IF DVAQP QA+IL NA+ +LK G Sbjct: 160 DLVEMSKRRPNIVPIVADARNPKAYRMLVGMVDCIFMDVAQPDQARILAINAKQFLKADG 219 Query: 173 YGMIAVKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 + MI++K+ ID T EP VF EVEK +E E++ LEP+E+DHA+ V Sbjct: 220 WFMISIKAPCIDSTIEPAVVFAAEVEKMKAEQLRPKEQITLEPFERDHAVVV 271 >gb|AAC32120.1| (AF051216) probable fibrillarin [Picea mariana] Length = 249 Score = 203 bits (511), Expect = 2e-51 Identities = 108/228 (47%), Positives = 149/228 (64%), Gaps = 8/228 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----EYRIWNPHRS 56 V ++ H+ GV+I + + + TKN+ G+ VYGE+ I + E EYR+WNP RS Sbjct: 8 VVIEPHRHEGVFIAKAKE--DALVTKNMAAGESVYGEKRISVQNEDSTKTEYRVWNPFRS 65 Query: 57 KLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVP 116 KL AAI+ G+ N IKPG VLYLG ASGTT SHVSD++G G ++ +E S R R+LV Sbjct: 66 KLAAAILGGVDNIWIKPGTHVLYLGAASGTTVSHVSDIVGPTGIVYAVEMSHRSGRDLVN 125 Query: 117 IVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMI 176 + + R N++PI+ DA P YR LV VDVIF DVAQP QA+I+ NA +LK GG+ ++ Sbjct: 126 MAKKRTNVIPIIEDARYPVRYRMLVGMVDVIFADVAQPDQARIVALNAHYFLKNGGHFVL 185 Query: 177 AVKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 ++K+ ID T E VF +EV+K E F+ E++ LEP+E+DHA V Sbjct: 186 SIKANCIDSTVPAEAVFAQEVKKLQKEQFKPFEQVTLEPFERDHACVV 233 >sp|Q24957|FBRL_GIALA FIBRILLARIN >gi|11280294|pir||T47231 fibrillarin [imported] - Giardia intestinalis >gi|520825|gb|AAA21687.1| (L28115) fibrillarin [Giardia intestinalis] Length = 327 Score = 201 bits (506), Expect = 6e-51 Identities = 107/228 (46%), Positives = 149/228 (64%), Gaps = 8/228 (3%) Query: 4 VKKH-KFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEE----YRIWNPHRSKL 58 VK H K+ G++I + + TK+L PG VYGE+ I EG E YR WNP RSKL Sbjct: 96 VKPHPKYDGIFI--SHGRGDVLVTKSLAPGVAVYGEKRISVEGTESKIEYREWNPFRSKL 153 Query: 59 GAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIV 118 GAA+ + + PIKPG VLYLG ASGTT SHVSD++G G ++ +EFS R R+L+ + Sbjct: 154 GAAVRLNVLDMPIKPGAKVLYLGAASGTTVSHVSDIVGPTGAVYAVEFSQRSGRDLLEVA 213 Query: 119 EDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAV 178 + R N+ PI+ DA P +YR +VP+VD IF DVAQP QA+I+ +NA YLK G +I++ Sbjct: 214 KARTNVYPIIADARHPYKYRMIVPEVDCIFSDVAQPDQARIVAENARYYLKANGGMLISI 273 Query: 179 KSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFVVR 225 K+ S+D T +PE VF RE+E F+ E+L++ + ++HA+ V R Sbjct: 274 KASSVDSTLKPEAVFAREIETLREHDFKCKEQLDIGEFHRNHAIVVGR 321 >gb|AAF71690.1|AF168719_1 (AF168719) fibrillarin [Trypanosoma brucei rhodesiense] Length = 300 Score = 199 bits (500), Expect = 3e-50 Identities = 105/222 (47%), Positives = 150/222 (67%), Gaps = 10/222 (4%) Query: 10 PGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKW-------EGEEYRIWNPHRSKLGAAI 62 PGV+I ++ + T N+VPG VYGE+ ++ E +EYR+WNP+RSKL AAI Sbjct: 69 PGVFI--SKGKADSLCTLNMVPGVSVYGEKRVEVGATQSGDEKKEYRLWNPYRSKLAAAI 126 Query: 63 MNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRK 122 G+ + +KPG VLYLG ASGTT SHVSD++G EG ++ +EFS R R+LV + + R Sbjct: 127 YAGIGSIHMKPGSKVLYLGAASGTTVSHVSDLVGPEGMVYAVEFSNRSGRDLVDMSKRRP 186 Query: 123 NIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRS 182 NIVPI+ DA P +YR L+P VD IF DVAQP QA+IL NA+ +LK GG+ +I++K+ Sbjct: 187 NIVPIIEDARYPMKYRMLMPMVDCIFMDVAQPDQARILALNAQAFLKNGGHYVISIKANC 246 Query: 183 IDVTKE-PEQVFREVEKELSEYFEVIERLNLEPYEKDHALFV 223 ID T + P + E++K + + +E+ +LEP+E+DHA+ V Sbjct: 247 IDSTLDAPVVIAAELDKLRKDRLKPLEQASLEPFERDHAVVV 288 >sp|P35551|FBRL_SCHPO FIBRILLARIN >gi|422056|pir||S33690 fibrillarin - fission yeast (Schizosaccharomyces pombe) >gi|296704|emb|CAA49550.1| (X69930) fibrillarin [Schizosaccharomyces pombe] >gi|3687500|emb|CAA21168.1| (AL031788) fibrillarin. [Schizosaccharomyces pombe] Length = 305 Score = 196 bits (493), Expect = 2e-49 Identities = 106/228 (46%), Positives = 148/228 (64%), Gaps = 8/228 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----EYRIWNPHRS 56 V ++ H+ GV+I + + + T+NLVPG+ VY E+ I + EYR+WNP RS Sbjct: 73 VIIEPHRHAGVFIARGKE--DLLVTRNLVPGESVYNEKRISVDSPDGTKVEYRVWNPFRS 130 Query: 57 KLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVP 116 KL A I+ GL N IKPG VLYLG A+GT+ SHV+DV+G EG ++ +EFS R R+L+ Sbjct: 131 KLAAGILGGLDNIYIKPGARVLYLGAANGTSVSHVADVVGPEGLVYAVEFSHRSGRDLLN 190 Query: 117 IVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMI 176 + + R N++PI+ DA ++YR LV VDV+F DVAQP QA+I+ NA +LK G +I Sbjct: 191 MAKKRTNVIPIVEDARHVQKYRMLVGMVDVVFADVAQPDQARIVALNAAAFLKNEGGVVI 250 Query: 177 AVKSRSIDVTKEPEQVF-REVEKELSEYFEVIERLNLEPYEKDHALFV 223 +VK+ ID T + VF REV+K E + E+L LEPYE+DH + V Sbjct: 251 SVKASCIDSTADAAVVFAREVKKMQEEKIKPQEQLTLEPYERDHCIIV 298 >sp|P35549|FBRL_LEIMA FIBRILLARIN >gi|425152|gb|AAA67420.1| (L26252) fibrillarin [Leishmania major] Length = 297 Score = 189 bits (474), Expect = 3e-47 Identities = 103/222 (46%), Positives = 149/222 (66%), Gaps = 11/222 (4%) Query: 10 PGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKW-------EGEEYRIWNPHRSKLGAAI 62 PGV+I ++ + T N+VPG VYGE+ I+ + +EYR+WNP+RSKL +AI Sbjct: 68 PGVFI--SKAKTDSLCTLNMVPGISVYGEKRIELGATQGGDDKKEYRLWNPYRSKLASAI 125 Query: 63 MNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRK 122 G+ + + PG VLYLG A+GTT SHVSD++G EG ++ +EFS RV R+LV + R+ Sbjct: 126 YAGVSSIHMGPGSKVLYLGGATGTTVSHVSDLVGPEGMVYAVEFSHRVGRDLVE-MSKRR 184 Query: 123 NIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRS 182 IVPI+ DA P +YR LVP VD IF DVAQP QA+IL NA+ +L+ GG+ +I++K+ Sbjct: 185 PIVPIVEDARYPMKYRMLVPMVDCIFMDVAQPDQARILALNAQAFLQNGGHYVISIKANC 244 Query: 183 IDVTKE-PEQVFREVEKELSEYFEVIERLNLEPYEKDHALFV 223 ID T E P + E+ K + + +E+++LEP+E+DHA+ V Sbjct: 245 IDSTLEAPVVIASELNKLKKDKLKPLEQVSLEPFERDHAVVV 286 >sp|O53133|FLPA_METMA FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN >gi|11357085|pir||T47220 fibrillarin [imported] - Methanosarcina mazei (fragment) >gi|2791993|emb|CAA76128.1| (Y16231) fibrillarin [Methanosarcina mazei] Length = 193 Score = 187 bits (469), Expect = 1e-46 Identities = 92/188 (48%), Positives = 131/188 (68%), Gaps = 4/188 (2%) Query: 11 GVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGAAIMNGLKNFP 70 G++ V D ++++T NL PG+ VYGE++I EG+EYR W+P RSKLGA ++ + P Sbjct: 10 GIFEVTKD--KKQLSTLNLDPGKVVYGEKLISVEGDEYRTWDPRRSKLGAMVLKKF-DIP 66 Query: 71 IKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRKNIVPILGD 130 +K VLYLG ASGTT SHVSD++ EG ++ +EF+PR +R+ + + RKNI PIL D Sbjct: 67 LKRNSKVLYLGAASGTTVSHVSDIVS-EGAVYSVEFAPRSMRDFIGLASRRKNIFPILAD 125 Query: 131 ATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDVTKEPE 190 A KP+ Y +V VDVIF+DVAQP QA+I NA +LKK GY ++++K+RSID P+ Sbjct: 126 AGKPDSYAHIVEPVDVIFQDVAQPNQAEIAARNAVRFLKKDGYLLLSIKARSIDTAASPK 185 Query: 191 QVFREVEK 198 ++F+E K Sbjct: 186 EIFKEEVK 193 >dbj|BAB10546.1| (AB019226) fibrillarin-like [Arabidopsis thaliana] Length = 292 Score = 184 bits (462), Expect = 9e-46 Identities = 103/225 (45%), Positives = 139/225 (61%), Gaps = 8/225 (3%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGE-----EYRIWNPHRS 56 V V H+ GV++ ++ + TKNLVPG+ +Y E+ I + E EYR+WNPHRS Sbjct: 59 VLVTPHRHAGVFVA--KSKADALVTKNLVPGEIIYNEKRIFVQNEDRSTVEYRVWNPHRS 116 Query: 57 KLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVP 116 KL AI G+ N IKPG VLYLG +SG T SHVSD++G EG ++ +E S + L+ Sbjct: 117 KLADAITTGVDNIWIKPGVKVLYLGASSGYTVSHVSDIVGPEGCVYAVEHSDICGKVLMN 176 Query: 117 IVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMI 176 + E R N++PI+ DA P +YR LV VD+IF DV P QA IL NA +LK GG+ MI Sbjct: 177 MAEKRTNVIPIIEDARHPAKYRMLVGMVDIIFSDVNHPEQANILSLNASYFLKSGGHFMI 236 Query: 177 AVKSRSIDVTKEPEQVFR-EVEKELSEYFEVIERLNLEPYEKDHA 220 ++K+ SID T E V++ EVEK E E L+L+ E+ HA Sbjct: 237 SIKANSIDSTIAAETVYQMEVEKLQMEELRPTEILHLDSCEEKHA 281 >gi|11499669 fibrillarin (fib) [Archaeoglobus fulgidus] >gi|6016032|sp|O28192|FLPA_ARCFU FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN >gi|7450788|pir||F69510 fibrillarin (fib) homolog - Archaeoglobus fulgidus >gi|2648447|gb|AAB89169.1| (AE000960) fibrillarin (fib) [Archaeoglobus fulgidus] Length = 210 Score = 162 bits (407), Expect = 2e-39 Identities = 84/184 (45%), Positives = 125/184 (67%), Gaps = 6/184 (3%) Query: 36 YGERVIKWEGEEYRIWNPHRSKLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVI 95 YGE+V + YR W P RSKL A I+ G ++ + VLYLG ASGTT SH++D++ Sbjct: 25 YGEKVF----DGYREWVPWRSKLAAMILKG-HRLKLRGDERVLYLGAASGTTVSHLADIV 79 Query: 96 GWEGKIFGIEFSPRVLRELVPIVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVAQPT 155 EG I+ +E+S + +L+ +V +R NI+P+L DA+KP +Y +V KVD+I++D+AQ Sbjct: 80 D-EGIIYAVEYSAKPFEKLLELVRERNNIIPLLFDASKPWKYSGIVEKVDLIYQDIAQKN 138 Query: 156 QAKILIDNAEVYLKKGGYGMIAVKSRSIDVTKEPEQVFREVEKELSEYFEVIERLNLEPY 215 Q +IL NAE +LK+ G +I VK+RSID T EPE+VF+ V KE+ F++++ +L PY Sbjct: 139 QIEILKANAEFFLKEKGEVVIMVKARSIDSTAEPEEVFKSVLKEMEGDFKIVKHGSLMPY 198 Query: 216 EKDH 219 +DH Sbjct: 199 HRDH 202 >emb|CAC12078.1| (AL445066) fibrillarin-like pre-rRNA processing protein related protein [Thermoplasma acidophilum] Length = 230 Score = 152 bits (379), Expect = 5e-36 Identities = 80/192 (41%), Positives = 119/192 (61%), Gaps = 4/192 (2%) Query: 33 QRVYGERVIKWEGEEYRIWNPHRSKLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVS 92 ++VYGE +I++E YR W P RSKL AAI+ GL N PI S+LYLG ++GTT SHVS Sbjct: 36 KKVYGEDIIRFEHANYREWRPDRSKLAAAILKGLHNMPIGESSSILYLGASTGTTVSHVS 95 Query: 93 DVIGWEGKIFGIEFSPRVLRELVPIVEDRKNIVPILGDATKPEEYRALVPKVDVIFEDVA 152 D I G+I+ +E + +L+ + E R NI PIL DA PE YR V VDVI++D++ Sbjct: 96 D-IAPSGRIYAVEVAYEPFSKLLDLAEQRDNIYPILEDANLPERYRFFVDHVDVIYQDIS 154 Query: 153 QPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDVTKEPEQVFREVEKELSEYFEVIERLNL 212 Q Q I N + + + + + +K+RSI T++ + + R+ ++LS Y + E ++L Sbjct: 155 QRNQIAIFKRNMDEFQPRSAF--LVLKTRSIASTEDAKTILRKTIEQLSSY-NIREVIDL 211 Query: 213 EPYEKDHALFVV 224 PY+ DH L +V Sbjct: 212 SPYDTDHYLILV 223 >emb|CAA98571.1| (Z74061) ORF YDL014w [Saccharomyces cerevisiae] Length = 154 Score = 139 bits (348), Expect = 2e-32 Identities = 71/146 (48%), Positives = 101/146 (68%), Gaps = 1/146 (0%) Query: 81 GIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRKNIVPILGDATKPEEYRAL 140 G ASGT+ SHVSDV+G EG ++ +EFS R REL+ + + R NI+PI+ DA P++YR L Sbjct: 1 GAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRML 60 Query: 141 VPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDVTKEPEQVF-REVEKE 199 + VD +F DVAQP QA+I+ N+ ++LK G +I++K+ ID T + E VF REV+K Sbjct: 61 IGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKL 120 Query: 200 LSEYFEVIERLNLEPYEKDHALFVVR 225 E + +E+L LEPYE+DH + V R Sbjct: 121 REERIKPLEQLTLEPYERDHCIVVGR 146 >gb|AAD15623.1| (AC006950) FBRL_HUMAN [AA 1- 227]; 34 KD NUCLEOLAR SCLERODERMA ANTIGEN [Homo sapiens] Length = 227 Score = 138 bits (345), Expect = 4e-32 Identities = 72/144 (50%), Positives = 97/144 (67%), Gaps = 6/144 (4%) Query: 2 VEVKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGE-RVIKWEGE---EYRIWNPHRSK 57 V V+ H+ GV+I + + + TKNLVPG+ VYGE RV EG+ EYR WNP RSK Sbjct: 86 VMVEPHRHEGVFICRGKE--DALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSK 143 Query: 58 LGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPI 117 L AAI+ G+ IKPG VLYLG ASGTT SHVSD++G +G ++ +EFS R R+L+ + Sbjct: 144 LAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINL 203 Query: 118 VEDRKNIVPILGDATKPEEYRALV 141 + R NI+P++ DA P +YR L+ Sbjct: 204 AKKRTNIIPVIEDARHPHKYRMLI 227 >gb|AAG19552.1| (AE005045) fibrillarin; Fib [Halobacterium sp. NRC-1] Length = 210 Score = 127 bits (316), Expect = 1e-28 Identities = 79/208 (37%), Positives = 120/208 (56%), Gaps = 16/208 (7%) Query: 17 DDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGAAIMNGLKNFPIKPGKS 76 D+DG +AT+ G+ YGE V+ + +R W+ HRSKLGA GL + G + Sbjct: 14 DEDGV--LATR----GEPAYGEPVV----DGWRRWDAHRSKLGATFELGLDT-GLSGGDA 62 Query: 77 VLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVEDRKNIVPILGDATKPEE 136 VLYLG A+GTT SHV+D + G + +EF+PR + +L+ + + R+ + P+L DA PE Sbjct: 63 VLYLGAANGTTVSHVAD---FAGPTYAVEFAPRPVTDLLAVADSRERLFPLLKDARAPET 119 Query: 137 YRALVPK-VDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDVTKEPEQVFRE 195 Y +V VD I +DVA QA + + N + +L G + A+K+RS DVT +P VF + Sbjct: 120 YAHVVESGVDAIVQDVATRGQADVALSNRQ-FLADDGRLVAALKARSEDVTADPAAVFED 178 Query: 196 VEKELSEYFEVIERLNLEPYEKDHALFV 223 + L + +EV +EP+ +DH V Sbjct: 179 LLGRLRDGYEVRATARMEPFHEDHLAVV 206 >gb|AAF54870.1| (AE003697) CG10909 gene product [Drosophila melanogaster] Length = 349 Score = 121 bits (301), Expect = 6e-27 Identities = 75/228 (32%), Positives = 123/228 (53%), Gaps = 10/228 (4%) Query: 4 VKKHKFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEE----YRIWNPHRSKLG 59 ++ H+ GVY++ + + ++ T+N YGER + E E +R+W+P +SKL Sbjct: 114 IEPHRHYGVYLLRNRFDAIQLLTRNTSSSADDYGERRVISEYREMRCEFRVWSPFQSKLA 173 Query: 60 AAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDVIGWEGKIFGIEFSPRVLRELVPIVE 119 A IM G+ + ++ G VLYLG G + SH+SD++G G ++ +E P R+L + Sbjct: 174 AGIMGGVSDLHLQIGSKVLYLGAGFGRSVSHISDIVGDSGMVYAVEQIPWAGRQLTIMAN 233 Query: 120 DRKNIVPILGDATKPEEYRALVPK-VDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMI-- 176 R NIVPI+ DAT P +YR VP +D+IF D+ + L+ NA +L GG+ + Sbjct: 234 RRSNIVPIVEDATMPYKYRYEVPACIDIIFADLPPSVLIRALMLNARHFLNPGGHFVAYL 293 Query: 177 -AVKSRSIDVTKEPEQVFREVEKELSEYFEVIERLNLEPYEKDHALFV 223 + S+ + K+ R + KE + E E + LEP++ +A V Sbjct: 294 HSPTSQGVVFNKDSFAAERRLLKE--KQLEPKEMVLLEPFKAGYAFVV 339 >gb|AAG21982.1| (AF263383) SKP1 interacting partner 7 [Arabidopsis thaliana] Length = 100 Score = 80.8 bits (196), Expect = 1e-14 Identities = 44/85 (51%), Positives = 58/85 (67%), Gaps = 1/85 (1%) Query: 140 LVPKVDVIFEDVAQPTQAKILIDNAEVYLKKGGYGMIAVKSRSIDVTKEPEQVFR-EVEK 198 LV VDVIF DVAQP QA+IL NA +LK GG+ +I++K+ ID T E VF+ EV+K Sbjct: 2 LVGMVDVIFSDVAQPDQARILALNASFFLKTGGHFVISIKANCIDSTVAAEAVFQSEVKK 61 Query: 199 ELSEYFEVIERLNLEPYEKDHALFV 223 E F+ E++ LEP+E+DHA V Sbjct: 62 LQQEQFKPAEQVTLEPFERDHACVV 86 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.317 0.139 0.401 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88239464 Number of Sequences: 2977 Number of extensions: 3715400 Number of successful extensions: 10746 Number of sequences better than 1.0e-10: 39 Number of HSP's better than 0.0 without gapping: 37 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 10636 Number of HSP's gapped (non-prelim): 40 length of query: 227 length of database: 189,106,746 effective HSP length: 54 effective length of query: 173 effective length of database: 156,788,448 effective search space: 27124401504 effective search space used: 27124401504 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 163 (67.9 bits)