BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2313 (PAB2313) DE:ATP-dependent RNA helicase, putative
(855 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75191 probable ATP-dependent RNA helicase PAB2313 - Pyroco... 1695 0.0
pir||A71223 hypothetical protein PH0044 - Pyrococcus horikoshii ... 1516 0.0
pir||C69187 conserved hypothetical protein MTH656 - Methanobacte... 640 0.0
pir||H64474 hypothetical protein MJ1401 - Methanococcus jannasch... 603 e-171
gb|AAG20308.1| (AE005105) DNA repair protein; Rad24a [Halobacter... 433 e-120
pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii ... 204 4e-51
pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus ab... 198 3e-49
pir||T43854 helicase [imported] - Pyrococcus furiosus >gi|337450... 190 7e-47
gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus] 178 3e-43
pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain... 171 4e-41
gb|AAK42601.1| DNA helicase related protein [Sulfolobus solfatar... 166 7e-40
gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacter... 162 2e-38
pir||C64440 DNA repair protein RAD24 homolog (intein-containing)... 148 3e-34
pir||C69208 DNA helicase related protein - Methanobacterium ther... 147 5e-34
emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermop... 144 4e-33
gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharom... 116 7e-25
gb|AAF49564.2| (AE003529) CG5931 gene product [Drosophila melano... 114 5e-24
dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens] 110 7e-23
emb|CAB60351.1| (AL110485) contains similarity to Pfam domain: P... 108 2e-22
gi|6321710 Ygr271wp [Saccharomyces cerevisiae] >gi|1723776|sp|P5... 108 3e-22
gb|AAC49699.1| (U35242) G9365 ORF [Saccharomyces cerevisiae] 108 3e-22
emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo s... 107 6e-22
dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens] 106 8e-22
pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabi... 104 3e-21
gi|9755332 C4 zinc finger DNA-binding protein of low sequence sp... 104 3e-21
pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (str... 102 1e-20
gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melano... 102 2e-20
pir||T39188 probable U5 snRNP-specific 200kd protein - fission y... 102 2e-20
gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus ... 100 6e-20
gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus] 99 1e-19
gb|AAG20341.1| (AE005107) pre-mRNA splicing helicase; Brr2 [Halo... 99 1e-19
pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae) >gi|... 99 1e-19
sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22... 99 2e-19
pir||T27149 hypothetical protein Y54E2A.6 - Caenorhabditis elega... 98 4e-19
pir||C71004 probable ATP-dependent helicase - Pyrococcus horikos... 93 1e-17
pir||T39411 RNA helicase - fission yeast (Schizosaccharomyces po... 88 5e-16
pir||T09159 RNA helicase prh75 - spinach >gi|1488647|emb|CAA6819... 87 6e-16
dbj|BAA34508.1| (AB018331) KIAA0788 protein [Homo sapiens] 87 6e-16
pir||S76892 hypothetical protein - Synechocystis sp. (strain PCC... 87 1e-15
pir||A69140 ATP-dependent helicase - Methanobacterium thermoauto... 87 1e-15
emb|CAB59484.1| (AL132648) putative helicase [Streptomyces coeli... 87 1e-15
emb|CAC11967.1| (AL445065) Large helicase related protein [Therm... 86 1e-15
gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobu... 86 2e-15
dbj|BAB02697.1| (AB018114) helicase-like protein [Arabidopsis th... 85 2e-15
emb|CAA11251.1| (AJ223310) helicase [Streptomyces avermitilis] >... 85 4e-15
pir||T35049 probable ATP-dependent helicase - Streptomyces coeli... 83 2e-14
gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus] 82 3e-14
pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyr... 80 8e-14
pir||T20430 hypothetical protein E03A3.2 - Caenorhabditis elegan... 78 3e-13
gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus] 76 1e-12
emb|CAA22943.1| (AL035310) putative helicase [Mycobacterium leprae] 76 1e-12
gb|AAA24517.1| (M30198) recQ [Escherichia coli] 75 3e-12
gb|AAA67618.1| (M87049) DNA-dependent ATPase, DNA helicase [Esch... 75 3e-12
sp|Q10701|HELY_MYCTU PUTATIVE HELICASE HELY >gi|7478108|pir||G70... 75 3e-12
sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|... 75 3e-12
gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobu... 75 3e-12
sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGEN... 75 3e-12
pir||BVECRQ DNA helicase recQ - Escherichia coli (strain K-12) >... 75 3e-12
sp|P15043|RECQ_ECOLI ATP-DEPENDENT DNA HELICASE RECQ 75 3e-12
gi|6323844 has DNA helicase signature motifs; Sgs1p [Saccharomyc... 74 8e-12
emb|CAA68194.1| (X99938) RNA helicase [Arabidopsis thaliana] 73 1e-11
dbj|BAA97183.1| (AB019235) RNA helicase [Arabidopsis thaliana] 73 2e-11
pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported... 73 2e-11
gb|AAF59592.1| (AC024820) contains similarity to TR:O18475 [Caen... 72 2e-11
sp|P46064|YMR1_CAEEL PUTATIVE ATP-DEPENDENT DNA HELICASE K02F3.1... 72 3e-11
gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobact... 71 4e-11
gb|AAD18127.1| (U89166) ECORLD_ORF3; putative DNA enzyme; simila... 71 7e-11
pir||F72253 hypothetical protein TM1450 - Thermotoga maritima (s... 70 9e-11
gb|AAF40306.1|AF156667_1 (AF156667) RNA helicase [Vigna radiata] 70 9e-11
pir||H81794 ATP-dependent DNA helicase (EC 3.6.1.-) NMA2213 [imp... 70 9e-11
>pir||B75191 probable ATP-dependent RNA helicase PAB2313 - Pyrococcus abyssi
(strain Orsay) >gi|5457486|emb|CAB48977.1| (AJ248283)
ATP-dependent RNA helicase, putative [Pyrococcus abyssi]
Length = 855
Score = 1695 bits (4342), Expect = 0.0
Identities = 855/855 (100%), Positives = 855/855 (100%)
Query: 1 MLFVIRPGRKKGELEALVIENPPEKLSQIRNVKADRVLRLIMREGRLFKVLEGSQYRNPK 60
MLFVIRPGRKKGELEALVIENPPEKLSQIRNVKADRVLRLIMREGRLFKVLEGSQYRNPK
Sbjct: 1 MLFVIRPGRKKGELEALVIENPPEKLSQIRNVKADRVLRLIMREGRLFKVLEGSQYRNPK 60
Query: 61 EIEKLLRQSRIVLVNADEWEDYFKRRLMNKNVEKASLCRLCLLEGRITVLTEGNRIKYRG 120
EIEKLLRQSRIVLVNADEWEDYFKRRLMNKNVEKASLCRLCLLEGRITVLTEGNRIKYRG
Sbjct: 61 EIEKLLRQSRIVLVNADEWEDYFKRRLMNKNVEKASLCRLCLLEGRITVLTEGNRIKYRG 120
Query: 121 EYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITK 180
EYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITK
Sbjct: 121 EYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITK 180
Query: 181 WDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSA 240
WDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSA
Sbjct: 181 WDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSA 240
Query: 241 TASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRI 300
TASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRI
Sbjct: 241 TASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRI 300
Query: 301 KTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDG 360
KTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDG
Sbjct: 301 KTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDG 360
Query: 361 LIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWR 420
LIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWR
Sbjct: 361 LIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWR 420
Query: 421 LIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKI 480
LIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKI
Sbjct: 421 LIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKI 480
Query: 481 TEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH 540
TEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH
Sbjct: 481 TEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH 540
Query: 541 EKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNR 600
EKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNR
Sbjct: 541 EKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNR 600
Query: 601 LSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRATSMSFLLPREAEFI 660
LSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRATSMSFLLPREAEFI
Sbjct: 601 LSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRATSMSFLLPREAEFI 660
Query: 661 RENLDNMNPLDIAIMLSPFENAYLPGFLQREIESAVRGRISSNVFSSSFASVLEELDKII 720
RENLDNMNPLDIAIMLSPFENAYLPGFLQREIESAVRGRISSNVFSSSFASVLEELDKII
Sbjct: 661 RENLDNMNPLDIAIMLSPFENAYLPGFLQREIESAVRGRISSNVFSSSFASVLEELDKII 720
Query: 721 PEISPNAADKLFLIYQDFFNCPEEDCTEFAMLMMGKKIVELRRDGKEPSKISEHFRKVYG 780
PEISPNAADKLFLIYQDFFNCPEEDCTEFAMLMMGKKIVELRRDGKEPSKISEHFRKVYG
Sbjct: 721 PEISPNAADKLFLIYQDFFNCPEEDCTEFAMLMMGKKIVELRRDGKEPSKISEHFRKVYG 780
Query: 781 LILYPGDVFTWLDTLVRKLEAVQRIARVFGKRGAEMEAMIVQREIEEGRRFKGPRNNNLI 840
LILYPGDVFTWLDTLVRKLEAVQRIARVFGKRGAEMEAMIVQREIEEGRRFKGPRNNNLI
Sbjct: 781 LILYPGDVFTWLDTLVRKLEAVQRIARVFGKRGAEMEAMIVQREIEEGRRFKGPRNNNLI 840
Query: 841 GGEKSWRKVRRERKP 855
GGEKSWRKVRRERKP
Sbjct: 841 GGEKSWRKVRRERKP 855
>pir||A71223 hypothetical protein PH0044 - Pyrococcus horikoshii
>gi|3256429|dbj|BAA29112.1| (AP000001) 855aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 855
Score = 1516 bits (3881), Expect = 0.0
Identities = 747/854 (87%), Positives = 807/854 (94%)
Query: 1 MLFVIRPGRKKGELEALVIENPPEKLSQIRNVKADRVLRLIMREGRLFKVLEGSQYRNPK 60
MLFVIR GRKKGELEA +IENPPEKLSQIRNVKADR+ RLIMR+GRLFKVLEGSQYRNPK
Sbjct: 1 MLFVIREGRKKGELEAFLIENPPEKLSQIRNVKADRIFRLIMRDGRLFKVLEGSQYRNPK 60
Query: 61 EIEKLLRQSRIVLVNADEWEDYFKRRLMNKNVEKASLCRLCLLEGRITVLTEGNRIKYRG 120
EIEKLLR SRI+L +ADEWEDYF+++LMNKNVEKASLCRLCLLEGRITVLTEGNRIKYR
Sbjct: 61 EIEKLLRSSRIILADADEWEDYFRKKLMNKNVEKASLCRLCLLEGRITVLTEGNRIKYRN 120
Query: 121 EYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITK 180
EYICERCAEEELK ELR RFNS+GM EQAKRLL KFRDLDKVLYAFDPRFDPT+HPE+TK
Sbjct: 121 EYICERCAEEELKNELRVRFNSLGMLEQAKRLLAKFRDLDKVLYAFDPRFDPTEHPEVTK 180
Query: 181 WDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSA 240
WDELKAK ++VERM +DE+DIPE FK++LKLEGI ELLPVQVLAIK+GLL+GENLLVVSA
Sbjct: 181 WDELKAKHVRVERMKVDEVDIPESFKNVLKLEGITELLPVQVLAIKNGLLKGENLLVVSA 240
Query: 241 TASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRI 300
TASGKTLIGELAGIPKAL GKKMLFLVPLVALANQKYEDF+RRYSKLGLKVAIRVGMSRI
Sbjct: 241 TASGKTLIGELAGIPKALEGKKMLFLVPLVALANQKYEDFKRRYSKLGLKVAIRVGMSRI 300
Query: 301 KTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDG 360
KTREEPVVVDTGIDADIIVGTYEG+DYLLR+GKKIGNVGT+VIDEIHM+DDEERGPRLDG
Sbjct: 301 KTREEPVVVDTGIDADIIVGTYEGVDYLLRSGKKIGNVGTVVIDEIHMIDDEERGPRLDG 360
Query: 361 LIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWR 420
LIARLRKLYP AQFIGLSAT+GNP+ELA++LGMKLVLYDERPVDLERHL+IARNESEKWR
Sbjct: 361 LIARLRKLYPKAQFIGLSATVGNPQELARSLGMKLVLYDERPVDLERHLIIARNESEKWR 420
Query: 421 LIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKI 480
+IAKLCK E MR+SSKGFKGQTIVFTYSR+RCHELASFLTGKGLKAKPYHSGLPYKQRKI
Sbjct: 421 IIAKLCKAEVMRKSSKGFKGQTIVFTYSRKRCHELASFLTGKGLKAKPYHSGLPYKQRKI 480
Query: 481 TEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH 540
TEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH
Sbjct: 481 TEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH 540
Query: 541 EKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNR 600
EKGKVYL+VEPG+KYSAQM+ TEDEVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNR
Sbjct: 541 EKGKVYLIVEPGKKYSAQMDETEDEVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNR 600
Query: 601 LSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRATSMSFLLPREAEFI 660
LSVIEEVNSLTLGANRSA+KVLEKLEELGMV + G IVRVTPYGRA SMSFLLP E EFI
Sbjct: 601 LSVIEEVNSLTLGANRSAKKVLEKLEELGMVSIRGDIVRVTPYGRAVSMSFLLPSEGEFI 660
Query: 661 RENLDNMNPLDIAIMLSPFENAYLPGFLQREIESAVRGRISSNVFSSSFASVLEELDKII 720
RENL++M+PL +AI L PFENAYLPGFLQREIESAVRGRISSN+FSSSFASVLEELDKII
Sbjct: 661 RENLESMDPLGMAIHLLPFENAYLPGFLQREIESAVRGRISSNIFSSSFASVLEELDKII 720
Query: 721 PEISPNAADKLFLIYQDFFNCPEEDCTEFAMLMMGKKIVELRRDGKEPSKISEHFRKVYG 780
PEISPNAAD+LFLIYQDFFNC E+DCTEFAM M+ +KI ELRRDG EPSKISE+FRKVYG
Sbjct: 721 PEISPNAADRLFLIYQDFFNCLEQDCTEFAMEMLSRKIAELRRDGYEPSKISEYFRKVYG 780
Query: 781 LILYPGDVFTWLDTLVRKLEAVQRIARVFGKRGAEMEAMIVQREIEEGRRFKGPRNNNLI 840
LILYPGDVFTWLD L+RKLEA+QRIA VF K+ E EA++V++E+EEGRRFK + L
Sbjct: 781 LILYPGDVFTWLDGLIRKLEAIQRIAGVFKKKEVENEALLVKKELEEGRRFKVRGKDKLK 840
Query: 841 GGEKSWRKVRRERK 854
GGE+ W+K+ RER+
Sbjct: 841 GGEERWKKIARERR 854
>pir||C69187 conserved hypothetical protein MTH656 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621738|gb|AAB85161.1| (AE000845) ATP-dependent RNA
helicase related protein [Methanobacterium
thermoautotrophicum]
Length = 837
Score = 640 bits (1634), Expect = 0.0
Identities = 370/843 (43%), Positives = 522/843 (61%), Gaps = 39/843 (4%)
Query: 9 RKKGELEALVIENPPEKLS-----------QIRNVKAD-RVLRLIMREGRLFKVLEGSQY 56
R+K ++ + NP + L+ +IR+ +A R+ R + +G E
Sbjct: 10 RRKRSVDFIPAGNPKKILNTRRKPAYWGRLKIRSTEAGPRISRFTVEKG------ERETL 63
Query: 57 RNPKEIEKLLRQSRIVLVNAD-EWEDYFKRRLMNKNVEKASLCRLCLLEGRITVLTEGNR 115
R P E K+L++ ++L D E ED + A +C+ CL EG +TV++ +
Sbjct: 64 RKPSEALKILKKQAVILTGRDPEIEDLLSS--YGISYRYARVCQHCLHEGYLTVVSSRSS 121
Query: 116 IKYRGEYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQH 175
+ G+ IC RC +E +KREL+ F +RL+ + LDK+L PRFDP ++
Sbjct: 122 TVHAGQIICSRCVDELIKRELKFAGMDGSTFRNFRRLIRRGVSLDKILEMMSPRFDPLEN 181
Query: 176 PEITKWDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENL 235
E+T++D + ++ + R+ +D+L +PEKFK +LK EG L PVQVLA+ +GLLEGE+L
Sbjct: 182 HELTRYDTVTSESERTPRVPLDKLAVPEKFKRMLKREGNTVLRPVQVLAVDAGLLEGEDL 241
Query: 236 LVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRV 295
+VVSATASGKTLI ELAGIP+AL G+K ++L PLVALANQKY DFRRRYS L LK AI+V
Sbjct: 242 MVVSATASGKTLIAELAGIPRALGGEKFIYLTPLVALANQKYRDFRRRYSPLKLKTAIKV 301
Query: 296 GMSRIKTREEPVVVDTGID-ADIIVGTYEGIDYLLRAGKK--IGNVGTIVIDEIHMLDDE 352
GMSRI+ R+E + +T + ADI+VGTYEG+DY+LRAG+ +G+VG +VIDEIH L+DE
Sbjct: 302 GMSRIRARDELRIPETDVSKADIVVGTYEGMDYILRAGRSGILGDVGVVVIDEIHTLEDE 361
Query: 353 ERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIA 412
ERG RL G+I R+R+L+P AQ I LSAT+ N E+A G++LV YD RPV LERHLV +
Sbjct: 362 ERGSRLKGMIKRIRRLFPDAQIIALSATVKNNLEVASEFGLRLVEYDRRPVPLERHLVFS 421
Query: 413 RNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSG 472
R E +K LI +L + E S KGF+GQTIVFT SRR+ +A +LT +G++A YH+G
Sbjct: 422 RGEEDKKNLILRLAEREFSTESEKGFRGQTIVFTNSRRKTRLIADYLTRRGVRAAAYHAG 481
Query: 473 LPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLG 532
L Y++R+ E F +Q + +VTTAAL AGVDFPASQV+FE+L MGN+WL EF QMLG
Sbjct: 482 LSYRERQRIERAFASQELAAIVTTAALAAGVDFPASQVVFETLLMGNRWLMPNEFAQMLG 541
Query: 533 RAGRPLYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEIEEDNVL 592
RAGRP YH++G VY++ E G ++ + +E+ +ALKLL S +PV V +++E +N+L
Sbjct: 542 RAGRPSYHDRGVVYVLAEVGMEFDGE---SEEAMALKLLESGPDPVDVNYTEEDVLENIL 598
Query: 593 AH--ACVFNRLSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRATSMS 650
A + S I S L E L+ LE GM+ GG+ R T YG A S S
Sbjct: 599 ADITSGAIKSESEISPDPSWPL----DPEGALDILESHGMIVRDGGL-RATGYGVAVSKS 653
Query: 651 FLLPREAEFIRENLD--NMNPLDIAIMLSPFENAYLPGFLQREIESAVRGRISSNVFSSS 708
F+ +AE+IR +L + PLDIA+ L PFE AYL G L R + A R S N+ + S
Sbjct: 654 FIGVTDAEYIRGHLKGASRRPLDIALELEPFEGAYLSGRLHRALSRAAGARFSMNLMADS 713
Query: 709 FASVLEELDKIIPEISPNAADKLFLIYQDFFNCPEEDCTEFAMLM--MGKKIVELRRDGK 766
+L + D ++ ++ + + + DF +C D + + + I+ R G+
Sbjct: 714 TLDILSDGDNLV-KLDSKLQEAVLNLQMDFLSCECRDRPFCGCIQRRLSEHIIAERISGR 772
Query: 767 EPSKISEHFRKVYGLILYPGDVFTWLDTLVRKLEAVQRIARVFGKRGAEMEAMIVQREIE 826
+P +IS Y + YPGD+F+WLDT VR LE++ RIA F +R E + R IE
Sbjct: 773 DPVEISRGLLSRYQIQAYPGDIFSWLDTTVRALESIGRIASAFKRRRYLKECSGIVRAIE 832
Query: 827 EGR 829
+GR
Sbjct: 833 KGR 835
>pir||H64474 hypothetical protein MJ1401 - Methanococcus jannaschii
>gi|1592049|gb|AAB99409.1| (U67580) putative ATP
dependent RNA helicase [Methanococcus jannaschii]
Length = 808
Score = 603 bits (1539), Expect = e-171
Identities = 362/821 (44%), Positives = 510/821 (62%), Gaps = 32/821 (3%)
Query: 1 MLFVIRPGRKKGELEALVIENPPEKLSQIRN-VKADRVLRLIMREGRLFKVLEGSQYRNP 59
ML V +P +KK E+E + + E +++N K + + + +L++ G + P
Sbjct: 1 MLIVRKPKKKKDEIEIVKVGGKIEDGIEVKNNQKIFANYKKVGDKYKLYRCRVGDKLIQP 60
Query: 60 KEIEKLLRQSRIVLVNADEWEDYFKRRLMNKNVEKASLCRLCLLEGRITVLTEGNRIKYR 119
++ +LL+ +I ++ +E E + N + LC CLL+ LT NR +Y
Sbjct: 61 SKVLELLKSDKIFILKENEEEIEEVLKSYNLKFDYIELCPFCLLKNIYKRLTRNNRCRYG 120
Query: 120 GEYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEIT 179
IC C E+K E++ I F L++F+D+DKVL R +P PE+T
Sbjct: 121 NLEICINCGINEIKEEVKISEEFIEKF------LKRFKDVDKVLSLLRIR-NPLDKPELT 173
Query: 180 KWDELK-AKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVV 238
++D + ++ K+E IDELDIPE+ K+I+K GI+ELLPVQ L++K+GLL G++LL++
Sbjct: 174 RYDIITGSEEDKIENYKIDELDIPEELKEIIKSRGIEELLPVQTLSVKAGLLNGDDLLII 233
Query: 239 SATASGKTLIGELAGIPKALN-GKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGM 297
SAT+SGKTLIGELAGI + GKK LFLVPLVALANQKY +F+ RY KLG KV++RVG+
Sbjct: 234 SATSSGKTLIGELAGIKNLIKTGKKFLFLVPLVALANQKYLEFKERYEKLGFKVSLRVGL 293
Query: 298 SRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPR 357
RI + V V+T +DADIIVGTYEGIDYL+R K++ ++GT+VIDEIH L+ EERG R
Sbjct: 294 GRIGKK---VDVETSLDADIIVGTYEGIDYLIRT-KRLKDIGTVVIDEIHSLNLEERGAR 349
Query: 358 LDGLIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESE 417
LDGLI RLR L+ AQ I LSATIGNP+ELAK L KLVLY+ RPV LERH++ +N+
Sbjct: 350 LDGLIGRLRFLFKEAQKIYLSATIGNPKELAKQLNAKLVLYNGRPVPLERHIIFCKNDFA 409
Query: 418 KWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQ 477
K +I ++ K E S G++GQ ++FTYSR+R LA L KG+KA+ YH G+ Y +
Sbjct: 410 KLNIIKEIVKREWQNISKFGYRGQCLIFTYSRKRAEYLAKALKSKGIKAEFYHGGMEYIK 469
Query: 478 RKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRP 537
R+ E +F Q I VVTTAAL AGVDFPAS VI ESLAMG WL+ EF QM GRAGR
Sbjct: 470 RRKVEDDFANQKIQCVVTTAALSAGVDFPASTVILESLAMGADWLNPAEFQQMCGRAGRK 529
Query: 538 LYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEIEEDNVLA--HA 595
HE GKVYL+VE G+KY A+ME TEDEVA KLL + E V VE++++ EE+ +LA A
Sbjct: 530 GMHEIGKVYLLVEIGKKYHAKMENTEDEVAFKLLNAVPEDVKVEYNEDEEEEQILATISA 589
Query: 596 CVFNRLSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRATSMSFLLPR 655
+ NR I+ V +G S K+L LE GM+K + V++T YG A ++SFL P+
Sbjct: 590 GITNRYD-IDRVP--YIGRAFSLNKILSNLESYGMIKANND-VKLTNYGSAVAISFLYPK 645
Query: 656 EAEFIREN-LDNMNPLDIAIMLSPFENAYLPGFLQREIESAVRGRISSNVFSSSFASVLE 714
AE I+E ++N + + + PFEN YL L+ ++ + + S F + + E
Sbjct: 646 VAEKIKEGIIENKEIIKLITEIMPFENVYLSNNLKIKLSKILNINVPSRFF-DALEVIRE 704
Query: 715 ELDKIIPEISPNAADKLFLIYQDFFNCPEEDCTEFAMLMMGKKIVELRRDGKEPSKISEH 774
++KI + + L LI +F E+ + + I+ LR GK P +IS+
Sbjct: 705 GMEKIKDK---KLKEDLTLIIMEFEGVEVEE-------KILEMIINLRISGKTPGQISKT 754
Query: 775 FRKVYGLILYPGDVFTWLDTLVRKLEAVQRIARVFGKRGAE 815
+ + + Y GD++ +L+ L+ L+A +RIAR+F KR AE
Sbjct: 755 LYEEFKIQTYSGDIYYYLEQLLNLLDATERIARIFNKRYAE 795
>gb|AAG20308.1| (AE005105) DNA repair protein; Rad24a [Halobacterium sp. NRC-1]
Length = 592
Score = 433 bits (1102), Expect = e-120
Identities = 260/572 (45%), Positives = 363/572 (63%), Gaps = 33/572 (5%)
Query: 98 CRLCLLEGRITVLTEGNRIKYRGEYICERCAEEELKRELRARFNSIGMFE-QAKRLLEKF 156
CR C GR + LT I+ GE+IC CA EEL+REL G + + + LL
Sbjct: 15 CRYCAGRGRYSPLTAETAIEADGEFICRDCAVEELERELSFSGAVSGAAQDRLEELLFAE 74
Query: 157 RDLDKVLYAFDPRFDPTQHPEITKWDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKE 216
+DL+KV DP ++TK+DE+ A V+ + + ELD+ + + + + +E
Sbjct: 75 QDLEKVTGLLGGELDP----DLTKYDEVSATTDDVDPVAVSELDLHPDVQGLFE-DRFEE 129
Query: 217 LLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGK-KMLFLVPLVALANQ 275
LLPVQ LA+++GL+EG++ +VVSATA+GKTL+GE+AG+ + +G K+LFLVPLVALANQ
Sbjct: 130 LLPVQSLAVENGLVEGDDQMVVSATATGKTLVGEIAGLHRLQSGNGKLLFLVPLVALANQ 189
Query: 276 KYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKI 335
K+EDF+ Y L V IRVG SRI R++ D ADIIVGTYEGID+ LR G+ +
Sbjct: 190 KHEDFQDEYGHLA-NVTIRVGSSRI--RDDGHAFDPA--ADIIVGTYEGIDHALRTGRDL 244
Query: 336 GNVGTIVIDEIHMLDDEERGPRLDGLIARL----------RKLYPGAQFIGLSATIGNPE 385
G++GT+VIDE+H L +++RG RLDGLI+RL R Y GAQ++ LSAT+GNP
Sbjct: 245 GDIGTVVIDEVHTLKEDDRGHRLDGLISRLKYYCEQRREERAGYDGAQWVYLSATVGNPG 304
Query: 386 ELAKALGMKLVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVF 445
ELA L LV ++ERPV +ERH+ A + +EK + L + E + SS G++GQTI+F
Sbjct: 305 ELAGKLRANLVEFEERPVPIERHVTFA-DGAEKPDIENTLVRREFDQESSMGYRGQTIIF 363
Query: 446 TYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDF 505
T SRRRC+E++ L ++PYH+GL Y +RK E +F Q + VVTTAAL AGVDF
Sbjct: 364 TNSRRRCNEISRKLD---YPSRPYHAGLDYGERKSVERQFGDQDLAAVVTTAALAAGVDF 420
Query: 506 PASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYHEKGKVYLMVEPGRKYSAQMEGTEDE 565
PA+QVIF++LAMG +WLSV+EF QMLGRAGRP YH++GKVY++VEP Y + MEGTE+E
Sbjct: 421 PANQVIFDTLAMGIEWLSVQEFEQMLGRAGRPDYHDRGKVYVLVEPDASYHSSMEGTEEE 480
Query: 566 VALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNRLSVIEEVNSLTLGANRSAEKVLEKL 625
+A LL +E V+ + ++ + LA+ V + + +N +G + + L KL
Sbjct: 481 IAFTLLKGDMENVVTHYDEDAAVEETLANVTVGG--TAAKRLNDRMVG-DIPTKHALGKL 537
Query: 626 EELGMVKLHGGIVRVTPYGRATSMSFLLPREA 657
E + + T GRA + FL P A
Sbjct: 538 LEYEFI----DGLEPTDRGRAVTTHFLDPDSA 565
>pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii
>gi|3257700|dbj|BAA30383.1| (AP000005) 715aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 715
Score = 204 bits (513), Expect = 4e-51
Identities = 178/549 (32%), Positives = 273/549 (49%), Gaps = 94/549 (17%)
Query: 194 MTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAG 253
M ++EL I E+ K++LK GI EL P Q A+ SG+L+GEN L+ TASGKTLI E+A
Sbjct: 1 MKVEELRIDERIKEVLKKRGISELYPPQAEALTSGILKGENALIAIPTASGKTLIAEIAI 60
Query: 254 IPKAL-NGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTG 312
+ + L G K ++LVPL ALA +K+++F + + +LGLKVA+ G K D
Sbjct: 61 VNRLLKEGGKAVYLVPLKALAEEKFKEF-KDWEELGLKVAMATGDYDSK--------DEW 111
Query: 313 IDA-DIIVGTYEGIDYLLRAGKK-IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYP 370
+ DII+ T E D LLR G I NV +V+DEIH++ +RG L+ +I ++
Sbjct: 112 LGGYDIIIATAEKFDSLLRHGSSWIRNVKVLVVDEIHLIGSRDRGATLEFIITQMLN--- 168
Query: 371 GAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVI------ARNESEKWRLIAK 424
AQ IGLSATIGNPEELA+ L KL+ D RPV L R + ++EK+ +
Sbjct: 169 RAQIIGLSATIGNPEELAEWLNAKLIKSDWRPVKLRRGVFYQGFVFWEDGKTEKFNSWEE 228
Query: 425 LCKVEAMRRSSKGFKGQTIVFTYSRRRCHELA--------SFLTGKGLK----------- 465
L +A++R SKG ++VF RR+ + A +FLT K L+
Sbjct: 229 LV-YDAIKR-SKG----SLVFVNMRRKAEKTALELSKKIRNFLTKKELRELKELAESLEE 282
Query: 466 -------AKP-------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVI 511
AK +H+GL ++R + E F+ +I VVV T L AG++ PA +VI
Sbjct: 283 NPTNEKLAKALQGGVAFHHAGLGREERVLVEENFKKGLIKVVVATPTLSAGINTPAFRVI 342
Query: 512 FESL----AMGNKWLSVREFHQMLGRAGRPLYHEKGKVYLM---VEPGRKYSAQMEGTED 564
G + + + E QM+GRAGRP Y E G+ ++ EP ++G +
Sbjct: 343 VRDTWRYSEFGMERIPILEIQQMMGRAGRPKYDEVGEAIIVSTTEEPSTVMERYIKGKPE 402
Query: 565 EVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNRLSVIEEVNSL--TLGANRSAE--K 620
++ +L ++ I +LA FN S E + L T A + +
Sbjct: 403 KLFSQLS-----------NESILRGQILALIATFNFSSFREIYDFLERTFYAYQGKDPYT 451
Query: 621 VLEKLEELGMVKLHGGIVRVT--------PYGRATSMSFLLPREAEFIRENLDNM----N 668
+ +++ ++ L + +T P G T+ ++ P A+ ++ L + N
Sbjct: 452 LEDRIRDIVYFLLENEFIEITLDDEIKALPLGIRTAKLYIDPMTAKIFKDTLPKIEKDPN 511
Query: 669 PLDIAIMLS 677
PL I ++S
Sbjct: 512 PLGILHVIS 520
>pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus abyssi (strain
Orsay) >gi|5458306|emb|CAB49795.1| (AJ248285) DNA
HELICASE RELATED PROTEIN [Pyrococcus abyssi]
Length = 715
Score = 198 bits (497), Expect = 3e-49
Identities = 177/548 (32%), Positives = 262/548 (47%), Gaps = 92/548 (16%)
Query: 194 MTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAG 253
M + EL++ EK K+IL+ GI+EL P Q A+ SG+LEGENLLV TASGKTLI E+A
Sbjct: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
Query: 254 IPKAL-NGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTG 312
K L G K +++VPL ALA +K+ +F + + +LGLKVA+ G +++E +
Sbjct: 61 ANKLLEEGGKAVYIVPLKALAEEKFREF-KDWERLGLKVAMATG--DYDSKDEWLG---- 113
Query: 313 IDADIIVGTYEGIDYLLRAGKK-IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPG 371
DII+ T E D LLR G I +V +VIDEIH++ +RG L+ +I ++
Sbjct: 114 -KYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIIT---QMLGR 169
Query: 372 AQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVI------ARNESEKWRLIAKL 425
AQ IGLSATIGNPEELA+ L KL+ D RPV L + + SE++ +L
Sbjct: 170 AQIIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL 229
Query: 426 CKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGK------------------GLKAK 467
V + KG +VF RR+ + A L K L+
Sbjct: 230 --VYDAVKKGKG----ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN 283
Query: 468 P---------------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIF 512
P +H+GL +R + E F+ +I VVV T L AG++ PA +VI
Sbjct: 284 PTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVII 343
Query: 513 ESL----AMGNKWLSVREFHQMLGRAGRPLYHEKGKVYLM---VEPGRKYSAQMEGTEDE 565
G + + V E QM+GRAGRP Y E G+ ++ EP ++G ++
Sbjct: 344 RDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEK 403
Query: 566 VALKLLTSPIEPVIVEWSDEIEEDNVLAHACVF--NRLSVIEEVNSLTLGANRSAEKVL- 622
+ +L ++ I +LA F + I + T A++ + +
Sbjct: 404 LFSQLS-----------NESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYML 452
Query: 623 -EKLEELGMVKLHGGIVRVT--------PYGRATSMSFLLPREAEFIRENL----DNMNP 669
EK+ + L + VT P G T+ ++ P A+ ++ L N NP
Sbjct: 453 EEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNP 512
Query: 670 LDIAIMLS 677
L I M+S
Sbjct: 513 LGIFHMIS 520
>pir||T43854 helicase [imported] - Pyrococcus furiosus
>gi|3374506|dbj|BAA32016.1| (AB016521) helicase
[Pyrococcus furiosus]
Length = 720
Score = 190 bits (477), Expect = 7e-47
Identities = 138/390 (35%), Positives = 204/390 (51%), Gaps = 50/390 (12%)
Query: 194 MTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAG 253
M +DEL + E+ K LK GI+ P Q A+KSG+LEG+N L+ TASGKTLI E+A
Sbjct: 1 MRVDELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAM 60
Query: 254 IPKAL-NGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTG 312
+ + L G K +++VPL ALA +K+++F + + K+GL+VA+ G +++E +
Sbjct: 61 VHRILTQGGKAVYIVPLKALAEEKFQEF-QDWEKIGLRVAMATG--DYDSKDEWLG---- 113
Query: 313 IDADIIVGTYEGIDYLLRAGKK-IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPG 371
DII+ T E D LLR G I +V +V DEIH++ +RG L+ ++A +
Sbjct: 114 -KYDIIIATAEKFDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILAH---MLGK 169
Query: 372 AQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAM 431
AQ IGLSATIGNPEELA+ L +L++ D RPV L R + + + I + E +
Sbjct: 170 AQIIGLSATIGNPEELAEWLNAELIVSDWRPVKLRRGVFYQGFVTWEDGSIDRFSSWEEL 229
Query: 432 RRSSKGFKGQTIVFTYSRRRCHELASFLTG--KGLKAKP--------------------- 468
+ K ++F RR+ +A L+ K L KP
Sbjct: 230 VYDAIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEKL 289
Query: 469 ----------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESL--- 515
+H+GL +R + E F+ +I VV T L AG++ PA +VI +
Sbjct: 290 AKAIRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWRY 349
Query: 516 -AMGNKWLSVREFHQMLGRAGRPLYHEKGK 544
G + + + E HQMLGRAGRP Y E G+
Sbjct: 350 SDFGMERIPIIEVHQMLGRAGRPKYDEVGE 379
>gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus]
Length = 691
Score = 178 bits (446), Expect = 3e-43
Identities = 137/395 (34%), Positives = 205/395 (51%), Gaps = 49/395 (12%)
Query: 194 MTIDEL--DIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGEL 251
M ++EL I ILK EGI+EL P Q A++ + G+NLL+ TA+GKTL+ E+
Sbjct: 1 MKVEELAESISSYAVGILKEEGIEELFPPQAEAVEK-VFSGKNLLLAMPTAAGKTLLAEM 59
Query: 252 AGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDT 311
A + +A+ G K L++VPL ALA +KYE F +++ K+GL++ I G ++R+E +
Sbjct: 60 AMVREAIKGGKSLYVVPLRALAGEKYESF-KKWEKIGLRIGISTG--DYESRDEHLG--- 113
Query: 312 GIDADIIVGTYEGIDYLLR-AGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYP 370
D DIIV T E D L+R I V +V+DEIH+LD E+RG L+ L+ ++R++
Sbjct: 114 --DCDIIVTTSEKADSLIRNRASWIKAVSCLVVDEIHLLDSEKRGATLEILVTKMRRMNK 171
Query: 371 GAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWR---LIAKLCK 427
+ IGLSAT N E+A+ L + D RPV L V+ E + ++ K
Sbjct: 172 ALRVIGLSATAPNVTEIAEWLDADYYVSDWRPVPLVEG-VLCEGTLELFDGAFSTSRRVK 230
Query: 428 VEAMRRSSKGFKGQTIVFTYSRRRCHE--------LASFLTGKGLK-------------- 465
E + G +VF +RR + A ++ +GL+
Sbjct: 231 FEELVEECVAENGGVLVFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRK 290
Query: 466 --------AKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAM 517
A +H+GL QR++ E F+ I VVV T L AGV+ PA +VI SL
Sbjct: 291 LAECVRKGAAFHHAGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYR 350
Query: 518 ---GNKWLSVREFHQMLGRAGRPLYHEKGKVYLMV 549
+K + V E+ QM GRAGRP E+G+ ++V
Sbjct: 351 FDGYSKRIKVSEYKQMAGRAGRPGMDERGEAIIIV 385
>pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain K1)
>gi|5103582|dbj|BAA79103.1| (AP000058) 702aa long
hypothetical helicase [Aeropyrum pernix]
Length = 702
Score = 171 bits (428), Expect = 4e-41
Identities = 150/513 (29%), Positives = 246/513 (47%), Gaps = 77/513 (15%)
Query: 223 LAIKSGLLEGENLLVVSATASGKTLIGELAGIPK-ALNGKKMLFLVPLVALANQKYEDFR 281
+A+++G+ +GENL+V + T SGKT I +A + A G + +LVPL ++A +KY F
Sbjct: 1 MALQAGVEKGENLVVAAPTGSGKTFIALVAIVNSLARAGGRAFYLVPLKSVAYEKYTSFS 60
Query: 282 RRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIG-NVGT 340
S++GLK+ I VG R E PVV+ TYE D LLR + NV
Sbjct: 61 I-LSRMGLKLKISVGDFREGPPEAPVVI----------ATYEKFDSLLRVSPSLARNVSV 109
Query: 341 IVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDE 400
+++DEIH + D +RGP L+ +++R+ AQ +GLSAT+ N E+A+ +G K+V
Sbjct: 110 LIVDEIHSVSDPKRGPILESIVSRMLASAGEAQLVGLSATVPNAGEIAEWIGGKIVESSW 169
Query: 401 RPVDLERHL---VIARNESEKWRLIAKLCKVEAMRRSSKGFK--GQTIVFTYSRRRCHEL 455
RPV L ++ + + R + ++ + + +++ + GQ +VFTYSRRR L
Sbjct: 170 RPVPLREYVFKEYKLYSPTGGLREVPRVYGLYDLDLAAEAIEDGGQALVFTYSRRRAVTL 229
Query: 456 ASFLT---GKGLKAKP--------------------------------YHSGLPYKQRKI 480
A G+ L ++ +H+GLP RK
Sbjct: 230 AKRAAKRLGRRLSSREARVYSAEASRAEGAPRSVAEELASLIAAGIAYHHAGLPPSLRKT 289
Query: 481 TEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESL----AMGNKWLSVREFHQMLGRAGR 536
E F+A + VV +T L AGV+ PA +V+ +S A + + V E+ QM GRAGR
Sbjct: 290 VEEAFRAGAVKVVYSTPTLAAGVNLPARRVVIDSYYRYEAGFREPIRVAEYKQMAGRAGR 349
Query: 537 PLYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSD-EIEEDNVLAHA 595
P E G+ ++ E +++ ED ++ + +P E V + +L
Sbjct: 350 PGLDEFGEAIIVAE-------RLDRPEDLIS-GYIRAPPERVESRLAGLRGLRHFILGIV 401
Query: 596 CVFNRLSV--IEEVNSLTLGA------NRSAEKVLEKLEELGMVKLHGGIVRVTPYGRAT 647
+S+ IE+V+ LTL + + + +E L G+V++ G + T GR
Sbjct: 402 APEGEVSIGSIEKVSGLTLYSLQRGLPRETIARAVEDLSAWGLVEVKGWRIAATSLGREV 461
Query: 648 SMSFLLPREAEFIRENLDNM---NPLDIAIMLS 677
+ +L P RE + ++ N DI ++S
Sbjct: 462 AAVYLDPESVPVFREEVKHLSFDNEFDILYLIS 494
>gb|AAK42601.1| DNA helicase related protein [Sulfolobus solfataricus]
Length = 715
Score = 166 bits (417), Expect = 7e-40
Identities = 139/447 (31%), Positives = 210/447 (46%), Gaps = 80/447 (17%)
Query: 189 IKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLI 248
+++E M+ID+L +P DI+K GIK+L P Q A+K GLL+G LL+ S T SGKTLI
Sbjct: 3 LELEWMSIDDLKLPSNVIDIIKNRGIKKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKTLI 62
Query: 249 GELAGIPKAL-NGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPV 307
E+ I L NG K +++ PL AL N+KY F + + +G KVA+ G +
Sbjct: 63 AEMGIISFLLKNGGKAIYVTPLRALTNEKYLTF-KDWESIGFKVAMTSG--------DYD 113
Query: 308 VVDTGI-DADIIVGTYEGIDYLLRAGKK-IGNVGTIVIDEIHMLDDEERGPRLDGLIARL 365
D + + DII+ TYE +D L R + V+DE+H L+D ERGP ++ + R
Sbjct: 114 TDDAWLKNYDIIITTYEKLDSLWRHRPDWLNEANYFVLDELHYLNDPERGPVVESVTIRA 173
Query: 366 RKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWRLIAK- 424
++ + LSATI N +++AK LG + V + RPV L ++ + +++ ++ +
Sbjct: 174 KR----RNLLALSATISNYKQIAKWLGAEPVATNWRPVPLMEGVMYPERKKKEYTILFRD 229
Query: 425 --LCKVE------AMRRSSKGFKGQTIVFTYSRRRCH----------------------- 453
KV A S GQ +VF SR+
Sbjct: 230 NTARKVHGDDAIIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDEKAISEI 289
Query: 454 ---------------ELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAA 498
EL L KG+ +H+GL R I E F+ + I V+V T
Sbjct: 290 LKQLDDIEEGGSDEKELLKSLISKGVAY--HHAGLSKALRDIIEESFRKRKIKVIVATPT 347
Query: 499 LGAGVDFPASQVIFESLAMGNK-------WLSVREFHQMLGRAGRPLYHEKGKVYLMVEP 551
L AGV+ PA VI + N+ + V E+ QM GRAGRP + + G+ ++V
Sbjct: 348 LAAGVNLPARTVIIGDIYRFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGESIIVVRD 407
Query: 552 GRKYSAQMEGTEDEVALKLLTSPIEPV 578
+ D V K + S +EP+
Sbjct: 408 --------KEDVDRVFKKYILSDVEPI 426
>gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacterium sp. NRC-1]
Length = 783
Score = 162 bits (405), Expect = 2e-38
Identities = 152/533 (28%), Positives = 238/533 (44%), Gaps = 85/533 (15%)
Query: 201 IPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNG 260
+P D + EG++EL P Q A++ G+ EG NL+ TASGKTLI +LA + G
Sbjct: 9 LPGGVADHFEGEGVEELYPPQAEAVERGVTEGANLVASVPTASGKTLIAQLAMLSAIAEG 68
Query: 261 KKM---------LFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDT 311
L++VPL ALA +K ++F + + GL V + G R+ + D
Sbjct: 69 GDSPTFSGDGTALYIVPLRALAGEKAQEFEA-FERFGLSVGVSTGNYE---RDGARLADN 124
Query: 312 GIDADIIVGTYEGIDYLLRAGKK-IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYP 370
DI+V T E +D L+R G I ++ +V DE+H++DD+ RGP L+ +A+LR+
Sbjct: 125 ----DIVVATSEKVDSLVRNGAGWIDDLSCVVADEVHLVDDDHRGPTLEVTLAKLRQQVA 180
Query: 371 GAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIAR-----NESEKWRLIAKL 425
Q + LSAT+GN ELA L +LV D RP++L + + + ++ +
Sbjct: 181 DLQVVALSATVGNAGELAAWLDAELVDSDWRPIELRTGVHYGQSLHYDDGTQAELSVGSG 240
Query: 426 CKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFL---TGKGLK----------------- 465
+ A+ + G T+VF SRR A L TG L
Sbjct: 241 SQTAAVVADTLADDGSTLVFVNSRRNAEASARRLADVTGNALSSAERERLADIAAEIRGV 300
Query: 466 ----------------AKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQ 509
A +H+GL + R++ E F+ +++ V T L AGV+ PA +
Sbjct: 301 SDTETSDELADAVASGAAFHHAGLAREHRELVEEAFRDRLVKAVSATPTLAAGVNTPARR 360
Query: 510 VI------FESLAMGNKWLSVREFHQMLGRAGRPLYHEKGKVYLMVEPGRKYSAQMEGTE 563
V+ ++ A G + L V E HQM GRAGRP G+ L+ A
Sbjct: 361 VVVRDWQRYDGTAGGMQPLDVLEVHQMFGRAGRPGLDPYGEAVLL--------ANSHDEL 412
Query: 564 DEVALKLLTSPIEPVIVEWSDE--IEEDNVLAHACVFNRL-SVIEEVNSLTLGANRSAE- 619
+E+ + + + EPV + + E + + A A F + E TL A ++ +
Sbjct: 413 EELFDRYVYADPEPVRSKLAAEPALRTHVLAAIATGFTTTEDGLHEFLGGTLYATQTDDT 472
Query: 620 --------KVLEKLEELGMVKLHGGIVRVTPYGRATSMSFLLPREAEFIRENL 664
VL L+ G V+ G +R T G+ S ++ P A I + L
Sbjct: 473 GRLRSVTGDVLRYLDRNGFVERDGAALRATATGQLVSRLYVDPMSAATIIDGL 525
>pir||C64440 DNA repair protein RAD24 homolog (intein-containing) -
Methanococcus jannaschii >gi|1499976|gb|AAB99126.1|
(U67555) putative SKI2-family helicase [Methanococcus
jannaschii]
Length = 1195
Score = 148 bits (369), Expect = 3e-34
Identities = 121/356 (33%), Positives = 180/356 (49%), Gaps = 79/356 (22%)
Query: 203 EKFKDILKLEGIKELLPVQVLAIKSGLLE-GENLLVVSATASGKTLIGELAGIPKALNG- 260
+K +ILK GI EL P Q A++ GLL+ +N L+ TASGKTLIGE+A I L+G
Sbjct: 2 DKILEILKDFGIVELRPPQKKALERGLLDKNKNFLISIPTASGKTLIGEMALINHLLDGN 61
Query: 261 -----KKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDA 315
KK +F+VPL ALA++KYE+F+ +Y + GL++A+ +G D D
Sbjct: 62 KNPTNKKGIFIVPLKALASEKYEEFKSKYERYGLRIALSIG-------------DYDEDE 108
Query: 316 D-----IIVGTYEGIDYLLRAG-KKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLY 369
D +I+ T E +D L R I +V +V+DEIH+++DE RG L+ L+ +L++
Sbjct: 109 DLSKYHLIITTAEKLDSLWRHKIDWINDVSVVVVDEIHLINDETRGGTLEILLTKLKEF- 167
Query: 370 PGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLER---------------------- 407
Q IGLSATIGNP+ELA+ L +L++ D RPV+L++
Sbjct: 168 -NVQIIGLSATIGNPDELAEWLNAELIVDDWRPVELKKGIYKNEAIEFINGEIREIKAVD 226
Query: 408 -----HLVI------------------ARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIV 444
+LV+ A NE++K L L + E +R + +I+
Sbjct: 227 NNDIYNLVVDCVKEGGCCLVFCNTKRNAVNEAKKLNLKKFLTEEEKIRLKEIAEEILSIL 286
Query: 445 FTYSRRRCHELAS-FLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAAL 499
C LA L G +H+GL Y+ RKI E F+ ++I V+ T L
Sbjct: 287 -EPPTEMCKTLAECILNGSAF----HHAGLTYQHRKIVEDAFRKRLIKVICCTPTL 337
>pir||C69208 DNA helicase related protein - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621900|gb|AAB85310.1| (AE000858)
DNA helicase related protein [Methanobacterium
thermoautotrophicum]
Length = 690
Score = 147 bits (367), Expect = 5e-34
Identities = 116/383 (30%), Positives = 183/383 (47%), Gaps = 70/383 (18%)
Query: 214 IKELLPVQVLAIKSGLLEGE-NLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVAL 272
I+EL P Q AI++G LE E N ++ TASGKTL+G +A + + G ++++ VPL+++
Sbjct: 19 IRELNPAQRSAIEAGYLESEDNYIIAIPTASGKTLLGIIAALKTVMEGGRVIYTVPLLSI 78
Query: 273 ANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAG 332
N+K ++FR+ IRVG ++P +DI V +E D L R
Sbjct: 79 QNEKIKEFRKLEEH-----GIRVG-------KDPRT------SDIAVMVFESFDSLTRFS 120
Query: 333 KKI-GNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKAL 391
I V +++DE HM+ + RGP ++ I R R L P + + LSAT+ N +E+A L
Sbjct: 121 WNILREVDLLIVDEFHMIGEYTRGPVIESAITRARTLNPSVRIVALSATLSNMDEIAGWL 180
Query: 392 GMKLVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRR 451
++V +D RPV L R ++ ++E + + K V + S QT+ F +RR
Sbjct: 181 DARVVEHDYRPVPLHREVL----DTEMFGVREKNDVVLKVLERSLEDGSQTLAFVSTRRF 236
Query: 452 CHELASFL-------------------TGKGLKAKP-----------------------Y 469
LAS L GK L+ +
Sbjct: 237 TESLASHLADKISGKIPDDMVESFREVAGKVLEVPKSRGSPPTSTCLKLAECLEAGIAFH 296
Query: 470 HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFES----LAMGNKWLSVR 525
H+GL +QR+I E EF+ I ++ T +L GV+ P+ V+ + G + + V
Sbjct: 297 HAGLFNRQREIIEDEFRDGNILMITATPSLMYGVNLPSRTVVIRDYTRWTSQGPRRIPVF 356
Query: 526 EFHQMLGRAGRPLYHEKGKVYLM 548
++ QM GRAGRP Y + G YL+
Sbjct: 357 DYEQMSGRAGRPQYDDAGYSYLI 379
>emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermoplasma acidophilum]
Length = 674
Score = 144 bits (360), Expect = 4e-33
Identities = 151/522 (28%), Positives = 231/522 (43%), Gaps = 62/522 (11%)
Query: 194 MTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAG 253
M I EL F + +L Q +AI+ + +G N++V TA+GKTLI A
Sbjct: 1 MKISELGYDRAFLQLFDGNDF-QLYDHQRMAIEQ-IRKGRNVVVSVPTAAGKTLIAYSAI 58
Query: 254 IPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGI 313
K +++VPL +LA +K+ + R LGLKV + +G + P +
Sbjct: 59 YETFQRNLKSIYIVPLRSLAMEKFSELSR-LRDLGLKVKMSIG----DYDDSPDFIKR-- 111
Query: 314 DADIIVGTYEGIDYLLRAGKKIGN-VGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGA 372
D ++ T E D LL I N VG +V+DEIH + DE RGP L+ + + R + P
Sbjct: 112 -YDAVILTSEKADSLLHHDPYILNDVGLLVLDEIHTIGDESRGPTLETVASIARYVNPDV 170
Query: 373 QFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAMR 432
+ + LSAT+ N ELA L L+ D RPV L+ ++ R++ + +
Sbjct: 171 RILALSATVSNAMELASWLDASLIKSDFRPVPLKTG-ILYRDQLYLDGKRRSGVSINQII 229
Query: 433 RSSKGFKGQTIVFTYSRRRCHELASFLT---GKGLKAKP--------------------- 468
R + GQ ++F SR++ + A L G K
Sbjct: 230 RETVEDNGQVLMFVSSRKKAEDTARDLAQIFGSDANIKISSDETNVYDDMLNEILPRGVA 289
Query: 469 -YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAM----GNKWLS 523
+H+GL QR E EF+A+ I V+V T L AGV+ PA VI + G +L+
Sbjct: 290 FHHAGLSNDQRAFIEREFRARRIKVIVATPTLAAGVNLPARLVIVRDITRWGSDGISYLT 349
Query: 524 VREFHQMLGRAGRPLYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWS 583
E QM+GRAGRP Y + G + V Y E A L++ EPV+
Sbjct: 350 NMEIKQMIGRAGRPGYDQYGIGLIYVSSQSSY---------EAAKDYLSTDPEPVVSYLG 400
Query: 584 DEIE-EDNVLAHAC--VFNRLSVIEEVNSLTLGANRSAEKVLEK--------LEELGMVK 632
+E + N LA + S I + TL +++ + +LE+ LE+ G +K
Sbjct: 401 NEAKVRFNTLAAISMGLARSPSDIMKFYETTLFFSQNGKDLLEEKISASLKFLEKNGFIK 460
Query: 633 LHGGIVRVTPYGRATSMSFLLPREAEFIRENLDNMNPLDIAI 674
+R T G+ TS ++ P A + + D +D AI
Sbjct: 461 -QSPDLRTTQLGKVTSDLYIDPESALRLVDFFDGPADVDHAI 501
>gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharomyces
cerevisiae] >gi|731380|sp|P32639|BRR2_YEAST PRE-MRNA
SPLICING HELICASE BRR2 >gi|1077724|pir||S50675 pre-mRNA
splicing helicase BRR2 - yeast (Saccharomyces
cerevisiae) >gi|603413|gb|AAB64699.1| (U18922) Brr2p:
Putative ATP-dependent RNA helicase [Saccharomyces
cerevisiae] >gi|1699380|gb|AAB37500.1|
Rss1p=ATP-dependent RNA helicase homolog [Saccharomyces
cerevisiae, Peptide Mutant, 2163 aa]
Length = 2163
Score = 116 bits (289), Expect = 7e-25
Identities = 122/454 (26%), Positives = 199/454 (42%), Gaps = 106/454 (23%)
Query: 187 KRIKVERMTIDELDIPEKFKDILKLEGIKELL-------------------PVQVLAIKS 227
KR+K + DE+ IP K ++ E +KE+ P+Q +
Sbjct: 454 KRVKPQ---YDEIHIPAPSKPVIDYE-LKEITSLPDWCQEAFPSSETTSLNPIQSKVFHA 509
Query: 228 GLLEGENLLVVSATASGKTLIGELAGI--------PKA----LNGKKMLFLVPLVALANQ 275
N+L+ + T SGKT I L + PK L+ K++++ PL AL +
Sbjct: 510 AFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIVYIAPLKALVQE 569
Query: 276 KYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKI 335
+ +F+RR + LG+KVA G SR+ ++ +D + ++V T E D R +
Sbjct: 570 QVREFQRRLAFLGIKVAELTGDSRLSRKQ----ID---ETQVLVSTPEKWDITTRNSNNL 622
Query: 336 GNVGTI---VIDEIHMLDDEERGPRLDGLIAR------LRKLYPGAQFIGLSATIGNPEE 386
V + +IDEIH+L D +RGP L+ ++AR + YP + IGLSAT+ N E+
Sbjct: 623 AIVELVRLLIIDEIHLLHD-DRGPVLESIVARTFWASKYGQEYP--RIIGLSATLPNYED 679
Query: 387 LAKALGMK---LVLYDE--RPVDLERHL--VIARNESEKWRLIAKLCKVEAMRRSSKGFK 439
+ + L + L +D RP L + + RN +K + + C + + ++G
Sbjct: 680 VGRFLRVPKEGLFYFDSSFRPCPLSQQFCGIKERNSLKKLKAMNDACYEKVLESINEG-- 737
Query: 440 GQTIVFTYSRRRCHELASFLTGKGLKAK-------------------------------- 467
Q IVF +SR+ A++L K +
Sbjct: 738 NQIIVFVHSRKETSRTATWLKNKFAEENITHKLTKNDAGSKQILKTEAANVLDPSLRKLI 797
Query: 468 -----PYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAM----G 518
+H+GL R ++E F ++ V+V TA L GV+ PA VI + +
Sbjct: 798 ESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVIIKGTDVYSPEK 857
Query: 519 NKW--LSVREFHQMLGRAGRPLYHEKGKVYLMVE 550
W LS ++ QMLGRAGRP Y G+ ++ +
Sbjct: 858 GSWEQLSPQDVLQMLGRAGRPRYDTFGEGIIITD 891
>gb|AAF49564.2| (AE003529) CG5931 gene product [Drosophila melanogaster]
Length = 2149
Score = 114 bits (282), Expect = 5e-24
Identities = 120/406 (29%), Positives = 190/406 (46%), Gaps = 80/406 (19%)
Query: 212 EGIKELLPVQVLAIKSGLLEGENLLVVSATASGKT---LIGELAGIPKALNGK------- 261
EG K L +Q K+ L EN+L+ + T +GKT L+ + I K +N
Sbjct: 495 EGFKTLNRIQSRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQD 554
Query: 262 -KMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVG 320
K++++ P+ +L + +F RR + L V+ G ++ TRE+ +IV
Sbjct: 555 FKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGDHQL-TREQIAA------TQVIVC 607
Query: 321 TYEGIDYLLRAGKK---IGNVGTIVIDEIHMLDDEERGPRLDGLIAR----LRKLYPGAQ 373
T E D + R G + + V ++IDEIH+L D ERGP L+ L+AR + +
Sbjct: 608 TPEKWDIITRKGGERTFVSLVRLVIIDEIHLLHD-ERGPVLEALVARTIRNIETTQEEVR 666
Query: 374 FIGLSATIGNPEELAKALGMK----LVLYDE--RPVDLERHL--VIARNESEKWRLIAKL 425
+GLSAT+ N +++A L +K L +D RPV LE+ V + ++++++ ++
Sbjct: 667 LVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYRPVSLEQQYIGVTEKKALKRFQVMNEI 726
Query: 426 CKVEAMRRSSKGFKGQTIVFTYSRRR-----------CHE---LASFLTG---------- 461
+ M + + Q +VF +SR+ C E L SFL
Sbjct: 727 VYEKTMEHAG---RNQVLVFVHSRKETGKTARAVRDMCLEQDTLGSFLKEGSASMEVLRT 783
Query: 462 -----KGLKAK---PY-----HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPAS 508
K + K PY H+G+ R + E F + I V+V+TA L GV+ PA
Sbjct: 784 EAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAH 843
Query: 509 QVIFESLAMGN----KW--LSVREFHQMLGRAGRPLYHEKGKVYLM 548
VI + + N +W LS + QMLGRAGRP Y KG+ L+
Sbjct: 844 TVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILI 889
>dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens]
Length = 774
Score = 110 bits (272), Expect = 7e-23
Identities = 139/527 (26%), Positives = 219/527 (41%), Gaps = 109/527 (20%)
Query: 122 YICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPR---------FDP 172
Y +E+L RE R+R + L + DLD+ A PR F
Sbjct: 36 YQLHETEKEDLIREERSRRERVRQSRMDTDL--ETMDLDQGGEALAPRQVLDLEDLVFTQ 93
Query: 173 TQHPEITKWDELKAKRIKVERMTIDELDIP----------EKFKDILKL--------EGI 214
H K +L + +R +E+ +P E+ + KL EG
Sbjct: 94 GSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGF 153
Query: 215 KELLPVQVLAIKSGLLEGENLLVVSATASGKT---LIGELAGIPKALN--------GKKM 263
K L +Q ++ L ENLL+ + T +GKT L+ L I K +N K+
Sbjct: 154 KTLNRIQSKLYRAALETAENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKI 213
Query: 264 LFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYE 323
+++ P+ +L + F +R + G+ VA G ++ E IIV T E
Sbjct: 214 IYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLSKEEISA-------TQIIVCTPE 266
Query: 324 GIDYLLRAGKK---IGNVGTIVIDEIHMLDDEERGPRLDGLIAR----LRKLYPGAQFIG 376
D + R G + V I++DEIH+L D +RGP L+ L+AR + + IG
Sbjct: 267 KWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIG 325
Query: 377 LSATIGNPEELAKALGMK----LVLYDE--RPVDLERHLV--IARNESEKWRLIAKLCKV 428
LSAT+ N E++A L + L +D RPV LER V + ++++++ ++
Sbjct: 326 LSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLERTYVGITEKKAIKRFQIMNEIVYE 385
Query: 429 EAMRRSSKGFKGQTIVFTYSRRRCHELASFLTG--------------------------- 461
+ M + K Q +VF +SR+ + A +
Sbjct: 386 KIMEHAG---KNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAE 442
Query: 462 --KGLKAKP--------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVI 511
K L+ K +H+G+ R + E F + I V+V+TA L GV+ PA VI
Sbjct: 443 QCKNLELKDLLLYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVI 502
Query: 512 FESLAM----GNKW--LSVREFHQMLGRAGRPLYHEKGKVYLMVEPG 552
+ + +W L + QMLGRAGRP Y KG+ L+ G
Sbjct: 503 IKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHG 549
>emb|CAB60351.1| (AL110485) contains similarity to Pfam domain: PF00270 (DEAD/DEAH
box helicase), Score=204.5, E-value=3.2e-64, N=2~cDNA
EST yk45c4.3 comes from this gene~cDNA EST yk25a5.3
comes from this gene~cDNA EST yk34b6.3 comes from this
gene~cDNA EST yk35b7.3 co>
Length = 2145
Score = 108 bits (268), Expect = 2e-22
Identities = 146/592 (24%), Positives = 252/592 (41%), Gaps = 114/592 (19%)
Query: 161 KVLYAFDPRFDPTQHPEITKWDELKAKRIKVERMTIDELDIP----------EKFKDILK 210
K+L D F H K EL + ++ + +E+ +P EK + +
Sbjct: 401 KMLDLNDLTFSQGSHLMSNKRCELPDGSYRRQKKSYEEIHVPALKPRPFAEGEKLVSVSE 460
Query: 211 L--------EGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKA----- 257
L +G K L +Q S L E+LL+ + T +GKT + L + +
Sbjct: 461 LPKWAQPAFDGYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNVALLTMLQEIGNHLA 520
Query: 258 ------LNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDT 311
L+ K++++ P+ +L + F +R + G+ V G +++ +
Sbjct: 521 EDGSVKLDEFKIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSKEQF------ 574
Query: 312 GIDADIIVGTYEGIDYLLR-AGKKIGN--VGTIVIDEIHMLDDEERGPRLDGLIAR---- 364
+ +IV T E D + R G++ N V ++IDEIH+L D+ RGP L+ ++ R
Sbjct: 575 -MATQVIVCTPEKYDVVTRKGGERAYNQMVRLLIIDEIHLLHDD-RGPVLESIVVRTIRQ 632
Query: 365 LRKLYPGAQFIGLSATIGNPEELAKALGMK---LVLYDE--RPVDLERHLVIARNESEKW 419
+ + + + +GLSAT+ N +++A L +K L +D RPV LE+ I E +
Sbjct: 633 MEQNHDECRLVGLSATLPNYQDVATFLRVKPEHLHFFDNSYRPVPLEQQ-YIGVTEKKAL 691
Query: 420 RLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRR-----------CHE---LASFL------ 459
+ + +V + K Q +VF +SR+ C E L++F+
Sbjct: 692 KRFQAMNEVVYDKIMEHAGKSQVLVFVHSRKETAKTAKAIRDACLEKDTLSAFMREGSAS 751
Query: 460 ---------TGKGLKAK---PY-----HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAG 502
K L K PY H+G+ R + E F + I V+ +TA L G
Sbjct: 752 TEILRTEAEQAKNLDLKDLLPYGFAIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWG 811
Query: 503 VDFPASQVIFESLAMGN----KW--LSVREFHQMLGRAGRPLYHEKGKVYLMVEPGR-KY 555
V+ PA VI + + N +W L + QMLGRAGRP Y ++G+ L+ +Y
Sbjct: 812 VNLPAHTVIIKGTQIYNPEKGRWTELGALDIMQMLGRAGRPQYDDRGEGILITNHSELQY 871
Query: 556 SAQMEGTEDEVALKLLTS-----PIEPVIVEWSDEIEEDNVLAHACVFNRLSVIEEVNSL 610
+ + V ++++ E V+ S E N L + +F R+ + +
Sbjct: 872 YLSLMNQQLPVESQMVSRLTDMLNAEVVLGTVSSVSEATNWLGYTFLFVRMLKNPTLYGI 931
Query: 611 TLGANRSAEKVLEK------------LEELGMVKL--HGGIVRVTPYGRATS 648
T R A+ +LE+ L++ G++K GI++ T GR S
Sbjct: 932 THEQAR-ADPLLEQRRADLIHTACVLLDKAGLIKYDKRSGIIQATELGRIAS 982
>gi|6321710 Ygr271wp [Saccharomyces cerevisiae] >gi|1723776|sp|P53327|YG5O_YEAST
PUTATIVE HELICASE YGR271W >gi|2131712|pir||S64604
hypothetical protein YGR271w - yeast (Saccharomyces
cerevisiae) >gi|1323493|emb|CAA97301.1| (Z73056) ORF
YGR271w [Saccharomyces cerevisiae]
Length = 1967
Score = 108 bits (267), Expect = 3e-22
Identities = 133/542 (24%), Positives = 235/542 (42%), Gaps = 83/542 (15%)
Query: 182 DELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSAT 241
+ L+ K +K+ + L P I + K P+Q + + EN V S T
Sbjct: 1109 ETLQTKLLKLRPLPTSALQNPL----IESIYPFKYFNPMQTMTFYTLYNTNENAFVGSPT 1164
Query: 242 ASGKTLIGELA--GIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKL-GLKVAIRVGMS 298
SGKT++ ELA K GKK++++ P+ AL ++ +D+R++ + + G KV G S
Sbjct: 1165 GSGKTIVAELAIWHAFKTFPGKKIVYIAPMKALVRERVDDWRKKITPVTGDKVVELTGDS 1224
Query: 299 RIKTREEPVVVDTGIDADIIVGT---YEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERG 355
++ DA I++ T ++GI + K + +V I++DEIH+L +RG
Sbjct: 1225 LPDPKDVH-------DATIVITTPEKFDGISRNWQTRKFVQDVSLIIMDEIHLL-ASDRG 1276
Query: 356 PRLDGLIARLR----KLYPGAQFIGLSATIGNPEELAKALGMK-LVLYD----ERPVDLE 406
P L+ +++R+ + + +G+S + N ++A LG+K LY+ RPV L+
Sbjct: 1277 PILEMIVSRMNYISSQTKQPVRLLGMSTAVSNAYDMAGWLGVKDHGLYNFPSSVRPVPLK 1336
Query: 407 RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELA---------- 456
++ + L+ + K M ++F SRR+ A
Sbjct: 1337 MYIDGFPDNLAFCPLMKTMNKPVFMAIKQHSPDKPALIFVASRRQTRLTALDLIHLCGME 1396
Query: 457 -------------------SFLTGKGLKAK------PYHSGLPYKQRKITEMEFQAQMID 491
S +T LK +H+GL K R I+ FQ I
Sbjct: 1397 DNPRRFLNIDDEEELQYYLSQVTDDTLKLSLQFGIGLHHAGLVQKDRSISHQLFQKNKIQ 1456
Query: 492 VVVTTAALGAGVDFPASQVI------FESLAMGNKWLSVREFHQMLGRAGRPLYHEKGKV 545
+++ T+ L GV+ PA VI F++ G + + + + QM+GRAGRP Y G
Sbjct: 1457 ILIATSTLAWGVNLPAHLVIIKGTQFFDAKIEGYRDMDLTDILQMMGRAGRPAYDTTGTA 1516
Query: 546 YLMVEPGRK--YSAQME-GTEDEVAL-KLLTSPIEPVIVEWS--DEIEEDNVLAHACVFN 599
+ + +K Y + G E +L K+L + I S ++ E + L+ +F
Sbjct: 1517 IVYTKESKKMFYKHFLNVGFPVESSLHKVLDDHLGAEITSGSITNKQEALDFLSWTFLFR 1576
Query: 600 R-------LSVIEEVNSLTLGANRSA--EKVLEKLEELGMVKLHGGIVRVTPYGRATSMS 650
R + ++ ++ + + S+ + LE L E V LHG + TP+ +S
Sbjct: 1577 RAHHNPTYYGIEDDTSTAGVSEHLSSLIDSTLENLRESQCVLLHGDDIVATPFLSISSYY 1636
Query: 651 FL 652
++
Sbjct: 1637 YI 1638
>gb|AAC49699.1| (U35242) G9365 ORF [Saccharomyces cerevisiae]
Length = 1967
Score = 108 bits (267), Expect = 3e-22
Identities = 133/542 (24%), Positives = 235/542 (42%), Gaps = 83/542 (15%)
Query: 182 DELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSAT 241
+ L+ K +K+ + L P I + K P+Q + + EN V S T
Sbjct: 1109 ETLQTKLLKLRPLPTSALQNPL----IESIYPFKYFNPMQTMTFYTLYNTNENAFVGSPT 1164
Query: 242 ASGKTLIGELA--GIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKL-GLKVAIRVGMS 298
SGKT++ ELA K GKK++++ P+ AL ++ +D+R++ + + G KV G S
Sbjct: 1165 GSGKTIVAELAIWHAFKTFPGKKIVYIAPMKALVRERVDDWRKKITPVTGDKVVELTGDS 1224
Query: 299 RIKTREEPVVVDTGIDADIIVGT---YEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERG 355
++ DA I++ T ++GI + K + +V I++DEIH+L +RG
Sbjct: 1225 LPDPKDVH-------DATIVITTPEKFDGISRNWQTRKFVQDVSLIIMDEIHLL-ASDRG 1276
Query: 356 PRLDGLIARLR----KLYPGAQFIGLSATIGNPEELAKALGMK-LVLYD----ERPVDLE 406
P L+ +++R+ + + +G+S + N ++A LG+K LY+ RPV L+
Sbjct: 1277 PILEMIVSRMNYISSQTKQPVRLLGMSTAVSNAYDMAGWLGVKDHGLYNFPSSVRPVPLK 1336
Query: 407 RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELA---------- 456
++ + L+ + K M ++F SRR+ A
Sbjct: 1337 MYIDGFPDNLAFCPLMKTMNKPVFMAIKQHSPDKPALIFVASRRQTRLTALDLIHLCGME 1396
Query: 457 -------------------SFLTGKGLKAK------PYHSGLPYKQRKITEMEFQAQMID 491
S +T LK +H+GL K R I+ FQ I
Sbjct: 1397 DNPRRFLNIDDEEELQYYLSQVTDDTLKLSLQFGIGLHHAGLVQKDRSISHQLFQKNKIQ 1456
Query: 492 VVVTTAALGAGVDFPASQVI------FESLAMGNKWLSVREFHQMLGRAGRPLYHEKGKV 545
+++ T+ L GV+ PA VI F++ G + + + + QM+GRAGRP Y G
Sbjct: 1457 ILIATSTLAWGVNLPAHLVIIKGTQFFDAKIEGYRDMDLTDILQMMGRAGRPAYDTTGTA 1516
Query: 546 YLMVEPGRK--YSAQME-GTEDEVAL-KLLTSPIEPVIVEWS--DEIEEDNVLAHACVFN 599
+ + +K Y + G E +L K+L + I S ++ E + L+ +F
Sbjct: 1517 IVYTKESKKMFYKHFLNVGFPVESSLHKVLDDHLGAEITSGSITNKQEALDFLSWTFLFR 1576
Query: 600 R-------LSVIEEVNSLTLGANRSA--EKVLEKLEELGMVKLHGGIVRVTPYGRATSMS 650
R + ++ ++ + + S+ + LE L E V LHG + TP+ +S
Sbjct: 1577 RAHHNPTYYGIEDDTSTAGVSEHLSSLIDSTLENLRESQCVLLHGDDIVATPFLSISSYY 1636
Query: 651 FL 652
++
Sbjct: 1637 YI 1638
>emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo sapiens]
Length = 1701
Score = 107 bits (264), Expect = 6e-22
Identities = 117/410 (28%), Positives = 182/410 (43%), Gaps = 80/410 (19%)
Query: 212 EGIKELLPVQVLAIKSGLLEGENLLVVSATASGKT---LIGELAGIPKALN--------G 260
EG K L +Q ++ L ENLL+ + T +GKT L+ L I K +N
Sbjct: 41 EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDD 100
Query: 261 KKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVG 320
K++++ P+ +L + F +R + G+ VA G ++ E IIV
Sbjct: 101 FKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISA-------TQIIVC 153
Query: 321 TYEGIDYLLRAGKK---IGNVGTIVIDEIHMLDDEERGPRLDGLIAR----LRKLYPGAQ 373
T E D + R G + V IV+DEIH+L D +RGP L+ L+AR + +
Sbjct: 154 TPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVR 212
Query: 374 FIGLSATIGNPEELAKALGMK----LVLYDE--RPVDLERHLV--IARNESEKWRLIAKL 425
IGLSAT+ N E++A L + L +D RPV LE+ V + ++++++ ++
Sbjct: 213 LIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEI 272
Query: 426 CKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTG------------------------ 461
+ M + K Q +VF +SR+ + A +
Sbjct: 273 VYEKIMEHAG---KNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRT 329
Query: 462 -----KGLKAK---PY-----HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPAS 508
K L+ K PY H+G+ R + E F + I V+V+TA L GV+ PA
Sbjct: 330 EAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFGDKHIQVLVSTATLAWGVNLPAH 389
Query: 509 QVIFESLAM----GNKW--LSVREFHQMLGRAGRPLYHEKGKVYLMVEPG 552
VI + + +W L + QMLGRAGRP Y KG+ L+ G
Sbjct: 390 TVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHG 439
>dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens]
Length = 1811
Score = 106 bits (263), Expect = 8e-22
Identities = 140/527 (26%), Positives = 219/527 (40%), Gaps = 109/527 (20%)
Query: 122 YICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPR---------FDP 172
Y +E+L RE R+R + L + DLD+ A PR F
Sbjct: 36 YQLHETEKEDLIREERSRRERVRQSRMDTDL--ETMDLDQGGEALAPRQVLDLEDLVFTQ 93
Query: 173 TQHPEITKWDELKAKRIKVERMTIDELDIP----------EKFKDILKL--------EGI 214
H K +L + +R +E+ +P E+ + KL EG
Sbjct: 94 GSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGF 153
Query: 215 KELLPVQVLAIKSGLLEGENLLVVSATASGKT---LIGELAGIPKALN--------GKKM 263
K L +Q ++ L ENLL+ + T +GKT L+ L I K +N K+
Sbjct: 154 KTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKI 213
Query: 264 LFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYE 323
+++ P+ +L + F +R + G+ VA G ++ E IIV T E
Sbjct: 214 IYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISA-------TQIIVCTPE 266
Query: 324 GIDYLLRAGKK---IGNVGTIVIDEIHMLDDEERGPRLDGLIAR----LRKLYPGAQFIG 376
D + R G + V I++DEIH+L D +RGP L+ L+AR + + IG
Sbjct: 267 KWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIG 325
Query: 377 LSATIGNPEELAKALGMK----LVLYDE--RPVDLERHLV--IARNESEKWRLIAKLCKV 428
LSAT+ N E++A L + L +D RPV LE+ V + ++++++ ++
Sbjct: 326 LSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYE 385
Query: 429 EAMRRSSKGFKGQTIVFTYSRRRCHELASFLTG--------------------------- 461
+ M + K Q +VF +SR+ + A +
Sbjct: 386 KIMEHAG---KNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAE 442
Query: 462 --KGLKAK---PY-----HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVI 511
K L+ K PY H+G+ R + E F + I V+V+TA L GV+ PA VI
Sbjct: 443 QCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVI 502
Query: 512 FESLAM----GNKW--LSVREFHQMLGRAGRPLYHEKGKVYLMVEPG 552
+ + W L + QMLGRAGRP Y KG+ L+ G
Sbjct: 503 IKGTQVYSPEKGHWTELGALDILQMLGRAGRPQYDTKGEGILITSHG 549
Score = 87.8 bits (214), Expect = 5e-16
Identities = 98/392 (25%), Positives = 168/392 (42%), Gaps = 66/392 (16%)
Query: 219 PVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGK--KMLFLVPLVALANQK 276
P+Q + +N+ V + T SGKT+ E A + L + +++ P+ ALA Q
Sbjct: 1005 PIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQV 1064
Query: 277 YEDFRRRY-SKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK- 334
Y D+ ++ +L KV + G +T + ++ G +II+ T E D L R K+
Sbjct: 1065 YMDWYEKFQDRLNKKVVLLTG----ETSTDLKLLGKG---NIIISTPEKWDILSRRWKQR 1117
Query: 335 --IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQ----FIGLSATIGNPEELA 388
+ N+ V+DE+H++ E GP L+ + +R+R + + + LS+++ N +++A
Sbjct: 1118 KNVQNINLFVVDEVHLIGG-ENGPVLEVICSRMRNISSQIERPIRIVALSSSLSNAKDVA 1176
Query: 389 KALGMKLVLY-----DERPVDLERHLVIARNESEKWRLIAKLCKV-EAMRRSSKGFKGQT 442
LG + RPV LE H+ + RL++ V A+ + S K
Sbjct: 1177 HWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSP--KKPV 1234
Query: 443 IVFTYSRRRCHELA--------------SFLTGKGLKAKPY------------------- 469
IVF SR++ A FL PY
Sbjct: 1235 IVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGY 1294
Query: 470 -HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWL------ 522
H GL +R++ E F + I VVV + +L G++ A VI N +
Sbjct: 1295 LHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDY 1354
Query: 523 SVREFHQMLGRAGRPLYHEKGKVYLMVEPGRK 554
+ + QM+G A RPL ++G+ +M + +K
Sbjct: 1355 PIYDVLQMVGHANRPLQDDEGRCVIMCQGSKK 1386
>pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabidopsis thaliana
>gi|2673917|gb|AAB88651.1| (AC002561) putative U5 small
nuclear ribonucleoprotein-specific protein [Arabidopsis
thaliana]
Length = 2172
Score = 104 bits (258), Expect = 3e-21
Identities = 117/447 (26%), Positives = 202/447 (45%), Gaps = 95/447 (21%)
Query: 170 FDPTQHPEITKWDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGL 229
FD P ++K + K +K+ D+PE + + G+++L VQ + L
Sbjct: 468 FDEVHVPWVSKKFDSNEKLVKIS-------DLPEWAQPAFR--GMQQLNRVQSKVYGTAL 518
Query: 230 LEGENLLVVSATASGKTLIGELAGIPK-ALN----------GKKMLFLVPLVALANQKYE 278
+ +N+L+ + T +GKT + L + + LN K++++ P+ AL + +
Sbjct: 519 FKADNILLCAPTGAGKTNVAVLTILHQLGLNMNPGGTFNHGNYKIVYVAPMKALVAEVVD 578
Query: 279 DFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGN- 337
+R G+ V G + +E + IIV T E D + R K G+
Sbjct: 579 SLSQRLKDFGVTVKELSGDQSLTGQEIK-------ETQIIVTTPEKWDIITR---KSGDR 628
Query: 338 -----VGTIVIDEIHMLDDEERGPRLDGLIAR-LRKLYPGAQ---FIGLSATIGNPEELA 388
V ++IDEIH+LDD RGP L+ ++AR LR++ + +GLSAT+ N +++A
Sbjct: 629 TYTQLVRLLIIDEIHLLDD-NRGPVLESIVARTLRQIESTKEHIRLVGLSATLPNCDDVA 687
Query: 389 KALGMK----LVLYDE--RPVDLERHL--VIARNESEKWRLIAKLCKVEAMRRSSKGFKG 440
L + L ++D RPV L + + + +++L+ +C + + + K
Sbjct: 688 SFLRVDLKNGLFIFDRSYRPVPLGQQYIGINVKKPLRRFQLMNDICYQKVVAVAG---KH 744
Query: 441 QTIVFTYSRRRCHE-------------------------------LASFLTGKGLK-AKP 468
Q ++F +SR+ + LA L LK P
Sbjct: 745 QVLIFVHSRKETAKTARAIRDTAMANDTLSRFLKEDSQSREILKCLAGLLKNNDLKELLP 804
Query: 469 Y-----HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGN---- 519
Y H+GL R+I E +F+ + V+++TA L GV+ PA VI + + N
Sbjct: 805 YGFAIHHAGLTRTDREIVENQFRWGNLQVLISTATLAWGVNLPAHTVIIKGTQVYNPERG 864
Query: 520 KW--LSVREFHQMLGRAGRPLYHEKGK 544
+W LS + QM+GRAGRP Y ++G+
Sbjct: 865 EWMELSPLDVMQMIGRAGRPQYDQQGE 891
>gi|9755332 C4 zinc finger DNA-binding protein of low sequence specificity in
vitro; Probable 119 kD DNA/RNA helicase family member;
Hfm1p [Saccharomyces cerevisiae]
Length = 1187
Score = 104 bits (258), Expect = 3e-21
Identities = 130/553 (23%), Positives = 234/553 (41%), Gaps = 83/553 (15%)
Query: 166 FDPRFDPTQHPEITKWDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAI 225
FD + T E K ++ + K + + +P+ F+ + K E +Q A
Sbjct: 93 FDHDLEQTPDEEAKKPKKVTIR--KSAKKCLSTTILPDSFRGVFKFT---EFNKMQSEAF 147
Query: 226 KSGLLEGENLLVVSATASGKTLIGELAGIP------KALNGKKMLFLVPLVALANQKYED 279
S EN ++ S T SGKT++ ELA + N K++++ P +L + Y++
Sbjct: 148 PSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKN 207
Query: 280 FRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGN-- 337
+ + V + VGM T + + +II+ T E D L R
Sbjct: 208 WFPSF------VNLSVGMLTSDTSF--LETEKAKKCNIIITTPEKWDLLTRRWSDYSRLF 259
Query: 338 --VGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELA------K 389
V +++DEIH + E+RG L+ ++ R+ + +F+ LSAT+ N E+LA
Sbjct: 260 ELVKLVLVDEIHTIK-EKRGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNN 318
Query: 390 ALGMKLVLYDE--RPVDLERHLV----IARNESEKW-----------------RLIAKLC 426
L ++ +DE R V L + + +N+ +K R + C
Sbjct: 319 ELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFC 378
Query: 427 KVEAMRRSSKGFKGQTIVFTYSRRRCH-----ELASFLTGKGLKAKPYHSGLPYKQRKIT 481
A S+ F +F+ S++RC+ ++ + +G+ +H+G+ + R
Sbjct: 379 PTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIAF--HHAGISLEDRTAV 436
Query: 482 EMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFH-----QMLGRAGR 536
E EF A I+++ +T+ L GV+ PA VI + N ++E+ QM+GRAGR
Sbjct: 437 EKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNS-SEIQEYSDLDVLQMIGRAGR 495
Query: 537 PLYHEKGKVYLMVEPGRK--YSAQMEGT---EDEVALKLLTSPIEPVIVEWSDEIEED-N 590
P + G +M + K Y + GT E + L L+ +E IE N
Sbjct: 496 PQFETHGCAVIMTDSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAVN 555
Query: 591 VLAHACVFNRL----SVIEEVNSLT-------LGANRSAEKVLEKLEELGMVKLHGGIVR 639
L + + R + +EVN N+ + +L+ L ++ ++ + G +
Sbjct: 556 WLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVKVKIIDISNGEYK 615
Query: 640 VTPYGRATSMSFL 652
T YG A + ++
Sbjct: 616 STAYGNAMTRHYI 628
>pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (strain K1)
>gi|5105887|dbj|BAA81199.1| (AP000063) 977aa long
hypothetical protein [Aeropyrum pernix]
Length = 977
Score = 102 bits (253), Expect = 1e-20
Identities = 122/480 (25%), Positives = 208/480 (42%), Gaps = 54/480 (11%)
Query: 192 ERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGEL 251
E ++E +P ++L+ G K LLP+Q A + G N LVV+ T SGKT
Sbjct: 26 EWWAMEESAVPGWVLELLREAGYKSLLPIQEKAFPI-IYRGLNALVVAPTGSGKTEAALA 84
Query: 252 AGIPKALNGK-------KMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVG----MSRI 300
+ + NG+ K++++ PL AL R G V +R G SR
Sbjct: 85 PLLARLRNGRVASGGGVKVVYVTPLRALNRDLEGRVERLAGLFGYTVQVRHGDTVQSSRR 144
Query: 301 KTREEPVVVDTGIDADIIVGTYEGIDYLL---RAGKKIGNVGTIVIDEIHMLDDEERGPR 357
+ E P DI++ T E + LL RA + + +V+DEIH L + +RG
Sbjct: 145 RFLERP--------PDIVITTPESLALLLTVKRAKEVLKQARAVVVDEIHELMESKRGVE 196
Query: 358 LDGLIARLRKLYPG--AQFIGLSATIGNPE--ELAKALG----MKLVLYDERPVDLERHL 409
L + +L +L G Q IGLSAT+ A LG + +VL D P + + +
Sbjct: 197 LSLNLEKL-ELMAGRRLQRIGLSATVSRHSLYRAASLLGAGRHVSMVL-DTSPKEYDVRV 254
Query: 410 VIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGK-GLKAKP 468
V+ +E W V+A+ KG G ++F +R LA L+ + G +
Sbjct: 255 VVVGDEGRFWE-----NSVKAIAELVKGEGGSVLIFANTRSTVETLAFALSRELGEEVPA 309
Query: 469 YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFH 528
+H L R+ E +F+ + +V T++L G+D +A+ ++LS R+
Sbjct: 310 HHGSLSRHVRERVERDFKEGRVKAIVATSSLELGID-------VGRVALVVQFLSPRQVT 362
Query: 529 QMLGRAGRP--LYHEKGKVYLMVEPGRKYSAQMEGTEDEV-ALKLLTSPIEPVIVEWSDE 585
M+ RAGR + E+ + ++ E E V A + + +E + +
Sbjct: 363 AMVQRAGRSGHRFGERSRAVIVT-----IDNVFEVLESHVIAFRAMKGDLEDISIPKKPY 417
Query: 586 IEEDNVLAHACVFNRLSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGR 645
+ +A A + + +E V L + + +E++EE+ V ++R+ P G+
Sbjct: 418 DALAHFMAGAAIDSEPPTLEGVYKLAVSTAPYEDLKMEEVEEIARVLSDVRVIRLGPGGK 477
>gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melanogaster]
Length = 1809
Score = 102 bits (252), Expect = 2e-20
Identities = 107/379 (28%), Positives = 177/379 (46%), Gaps = 69/379 (18%)
Query: 234 NLLVVSATASGKTLIGELAGIPKALNGK---KMLFLVPLVALANQKYEDFRRRY--SKLG 288
N+L+ + T SGKT++ E+A I +ALN K++++ PL AL ++ D+ +R+ S LG
Sbjct: 980 NVLLGAPTGSGKTIVAEIA-IFRALNQNPKCKVVYIAPLKALVKERIADWEQRFQRSSLG 1038
Query: 289 LKVAIRVG---MSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDE 345
LKV G RE ++V T D I +++ +Y + +V IVIDE
Sbjct: 1039 LKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREY-------VQHVSLIVIDE 1091
Query: 346 IHMLDDEERGPRLDGLIARLRKLYP----GAQFIGLSATIGNPEELAKALGM-KLVLYD- 399
IH+L E+RGP ++ +++R + + +GLS + N ++LA LG+ K+ LY+
Sbjct: 1092 IHLL-GEDRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNF 1150
Query: 400 ---ERPVDLERHLVIARNESEKWRLIA-KLCKVEAMRRSSKGFKGQTIVFTYSRRRCH-- 453
RPV L+ H+ + R+ +A+R S TIVF SRR+
Sbjct: 1151 KPSVRPVPLQVHINGFPGKHYCPRMATMNRPTFQAIRTYSP--CEPTIVFVSSRRQTRLT 1208
Query: 454 --ELASFLTGKGLKAK------------------------------PYHSGLPYKQRKIT 481
+L +F+ G+ + +H+GL + RK
Sbjct: 1209 ALDLITFVAGESNPKQFLHIPEDEIELILQNIREQNLKFCLAFGIGLHHAGLQEQDRKCV 1268
Query: 482 EMEFQAQMIDVVVTTAALGAGVDFPASQVI------FESLAMGNKWLSVREFHQMLGRAG 535
E F + I ++V TA L GV+ PA V+ F+ + + + QM+GRAG
Sbjct: 1269 EELFLNRKIQILVATATLAWGVNLPAHLVVIKGTEYFDGKVKKYVDMPITDVLQMMGRAG 1328
Query: 536 RPLYHEKGKVYLMVEPGRK 554
RP + +G ++V +K
Sbjct: 1329 RPQFDNEGVAVVLVHDEKK 1347
Score = 90.1 bits (220), Expect = 9e-17
Identities = 110/449 (24%), Positives = 189/449 (41%), Gaps = 90/449 (20%)
Query: 171 DPTQHPEITKWDELKAKR-------IKVERMTIDELDIPEKFKDILKLEGIKELLPVQVL 223
D Q + +W+E+K + +R+ I+ELD + L KEL +Q +
Sbjct: 64 DNAQRIDNKQWEEVKIPASEPPPLSVGNKRVQIEELDDVGR----LAFANCKELNRIQSV 119
Query: 224 AIKSGLLEGENLLVVSATASGKTLIGELAGI--------PKALNGK--KMLFLVPLVALA 273
EN+LV + T +GKT + L+ + +N K++++ P+ ALA
Sbjct: 120 VFPVAYHSNENMLVCAPTGAGKTNVAMLSIVHTIRCHLEQGVINRDEFKIVYIAPMKALA 179
Query: 274 NQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGK 333
+ ++F +R L + V G ++ E I+V T E D + R G
Sbjct: 180 AEMVDNFSKRLKSLQIAVRELTGDIQLTKAEMAA-------TQILVTTPEKWDVVTRKGS 232
Query: 334 ----KIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQ----FIGLSATIGNPE 385
I V ++IDE+H+L ERGP ++ L+AR +L +Q +GLSAT+ N
Sbjct: 233 GDVALISLVELLIIDEVHLLHG-ERGPVVEALVARTLRLVESSQSMIRIVGLSATLPNYI 291
Query: 386 ELAKAL---GMKLVLYDE---RPVDLERHLVIARNESEKWRL--IAKLCKVEAMRRSSKG 437
++A L MK + Y + RPV L+ + V ++ + ++ + + C + + +G
Sbjct: 292 DVAHFLRVNPMKGLFYFDSRFRPVPLDTNFVGIKSVKQLQQIADMDQCCYQKCVEMVQEG 351
Query: 438 FKGQTIVFTYSRRRCHELASFL------------------TGKGLKAKP----------- 468
Q +VF ++R A+ + GL +
Sbjct: 352 H--QIMVFVHARNATVRTANVIRELAQQNNTSALFLPKDSAAHGLATRSIQRSRNKQLVE 409
Query: 469 --------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNK 520
+H+G+ R++ E F I V+V TA L GV+ PA VI + +
Sbjct: 410 LFSCGLAMHHAGMLRADRQMVEKYFVEGHISVLVCTATLAWGVNLPAHAVIIRGTDIYDA 469
Query: 521 W------LSVREFHQMLGRAGRPLYHEKG 543
L + + Q+ GRAGRP + + G
Sbjct: 470 KHGSFVDLGILDVLQIFGRAGRPQFDKSG 498
>pir||T39188 probable U5 snRNP-specific 200kd protein - fission yeast
(Schizosaccharomyces pombe) >gi|6014422|emb|CAB57421.1|
(AL121764) putative U5 snRNP-specific 200kd protein
[Schizosaccharomyces pombe]
Length = 2176
Score = 102 bits (252), Expect = 2e-20
Identities = 97/381 (25%), Positives = 171/381 (44%), Gaps = 80/381 (20%)
Query: 233 ENLLVVSATASGKTLIGELAGIPKA-----------LNGKKMLFLVPLVALANQKYEDFR 281
EN+L+ + T +GKT + L + + L K++++ PL AL + +F
Sbjct: 536 ENILLCAPTGAGKTNVAMLCILNELQKHLREDLSFNLQNFKIVYIAPLKALVQEMVNNFS 595
Query: 282 RRYSKLGLKVAIRVGMSRIKTR---EEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNV 338
+R + ++VA G S++ + E ++V T DII + Y + V
Sbjct: 596 KRLTPYNIRVAELTGDSQLTKQQISETQIIVTTPEKWDIITRKANDLSY-------VNLV 648
Query: 339 GTIVIDEIHMLDDEERGPRLDGLIARL----RKLYPGAQFIGLSATIGNPEELAKALGMK 394
++IDE+H+L DE RGP L+ ++AR+ + + +GLSAT+ N ++A L +
Sbjct: 649 RLVIIDEVHLLHDE-RGPVLESIVARIFRHQEETLEQVRLVGLSATLPNYTDVASFLHVD 707
Query: 395 ----LVLYDE--RPVDLERHLV--IARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFT 446
L +D RP L++ + + ++ + + C + M+ + K Q ++F
Sbjct: 708 PKKGLFYFDSTYRPCPLKQEFIGITEKTPFKRMQTTNEACYEKVMQHAGKN---QVLIFV 764
Query: 447 YSRRRCHELASFLTGKGLKAK--------------------------------PY----- 469
+SR+ + A F+ K L+ + PY
Sbjct: 765 HSRKETAKTARFIRDKALEEETIGHLLRSDAASREILRAEADSTSDENLKDLLPYGFAIH 824
Query: 470 HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNK----W--LS 523
H+G+ + R+ +E F I V+V+TA L GV+ PA VI + + + W LS
Sbjct: 825 HAGMRREDRQTSEDLFADGTIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGIWTELS 884
Query: 524 VREFHQMLGRAGRPLYHEKGK 544
++ QMLGRAGRP + G+
Sbjct: 885 PQDVLQMLGRAGRPQFDTYGE 905
>gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus]
>gi|7446072|pir||G69550 ATP-dependent RNA helicase
homolog AF2406 - Archaeoglobus fulgidus
>gi|2650686|gb|AAB91259.1| (AE001109) ATP-dependent RNA
helicase, putative [Archaeoglobus fulgidus]
Length = 766
Score = 100 bits (247), Expect = 6e-20
Identities = 145/539 (26%), Positives = 227/539 (41%), Gaps = 61/539 (11%)
Query: 121 EYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITK 180
E C +C LKR + R SI ++ LL+K + +L FD EI
Sbjct: 3 ELFCPQCGM--LKRRCKCRKRSIR--QRNLELLKKVGYKEFLLPLFDT------DDEIVL 52
Query: 181 WDELKAKRIKVERMTIDELD-IPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVS 239
+ L+ R K +ELD +P + L+ GI L P Q A+ L+EG ++++ +
Sbjct: 53 YKVLRPFREK----PTEELDFLPSELASCLRKRGIGRLYPFQKEAMIR-LMEGRDVVITA 107
Query: 240 ATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSR 299
T GKT + + +AL+G K + P ALA + E + S LGL+ G S
Sbjct: 108 PTGFGKTEAFAVPMLWRALHGGKAMVFYPTKALARDQEEKIKFYTSSLGLRAVRFDGDSG 167
Query: 300 IKTREEPVVVDTGIDADIIVGTYEGIDYLLR---AGKKI-GNVGTIVIDEIHMLDDEERG 355
REE V +G DII+ + +DY LR A ++I + I +DE+H G
Sbjct: 168 ---REERRAVLSG-KCDIILTNPDMVDYHLRNTPAFRRICRELSFIAVDELHTYTGV-LG 222
Query: 356 PRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKAL---GMKLVLYDERPVDLERHLVIA 412
+ L+ RL + + Q SAT+ N E A+ L LV + R L HL+
Sbjct: 223 SNMHYLVKRLSR-FAEFQIACASATLSNAAEFAEELFDRDFVLVSGEHRKGTL--HLIFR 279
Query: 413 RNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSG 472
S L + + ++ R+ K IVF S + + L GLK+ + SG
Sbjct: 280 YTPS----LYSAVREIVTALRNRK-----IIVFGNSYKSVETINLILRRHGLKSAIHKSG 330
Query: 473 LPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLG 532
LP + R+ E +F+ I++VV+T L GVD V+ L + + Q +G
Sbjct: 331 LPKEVREEVEAKFKRGEINIVVSTPTLELGVDIGDVDVVVSELVPYGQMI------QRVG 384
Query: 533 RAGRPLYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEIEEDNVL 592
RAGR G V L +D ++ T P + E + +E N
Sbjct: 385 RAGRKGQESVGVVILR-------------EDDSISTYYRTKPEDYFKEEANGYVERHN-- 429
Query: 593 AHACVFNRLSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRATSMSF 651
F +S+ E +R + ++++KL+ G+V G T S +F
Sbjct: 430 EEVMKFQLISMCIEKPVRLEELDRQSAEIMQKLQAQGIVVEREGAFHPTAKAIELSRAF 488
>gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 913
Score = 99.5 bits (244), Expect = 1e-19
Identities = 99/358 (27%), Positives = 169/358 (46%), Gaps = 33/358 (9%)
Query: 199 LDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKAL 258
+++ +F LK G ++L P+Q +AI +L G+N+L+++ T GKT L
Sbjct: 2 INVTNEFLVRLKKLGYEDLTPIQKIAIPK-VLSGKNVLIIAPTGYGKTEAAILPIFYTIF 60
Query: 259 NGK----KMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGID 314
K L++ PL AL RR + V +R G S K R+E ++D
Sbjct: 61 KDKPEKISTLYITPLRALNRDLELRLRRLGEAFNISVNVRHGDSSQKERKE--ILDN--P 116
Query: 315 ADIIVGTYEGIDYLLRAG---KKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYP- 370
D+++ T E + YL+ K N+ I+IDE+ + DE+RG L LI R++K+
Sbjct: 117 PDVLLVTPETLLYLVLNDTFRKYFTNLKWIIIDELQEMLDEKRGIELSVLIQRIKKIATR 176
Query: 371 -GAQFIGLSATIGNPEELAKAL---GMKLVLYDERPVDLERHLVIARNESEKWRLIAKL- 425
Q IG+SATIG+ E + L G + D++ L++ + E + L KL
Sbjct: 177 NKIQLIGISATIGDVEIAKRYLDREGEVEIANINAIKDIKVDLILPKVEKKDADLAVKLG 236
Query: 426 ------CKVEAMRRSSKGFKGQTIVFTYSRRRCHELAS-FLTGKGLKAKPYHSGLPYKQR 478
++E + K K I+FT +R +A+ ++ LK +H L + R
Sbjct: 237 LRPDTIARLEKLNEIIKNNK-PIIIFTNTRETSEFIANQLMSNYSLKIASHHGSLSREIR 295
Query: 479 KITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
TE +F+ ID +V T++L G+D ++ + ++S R+ +++ R GR
Sbjct: 296 IKTENDFKNGNIDAIVATSSLELGIDIGRINLVVQ-------YMSPRQVIRLIQRVGR 346
>gb|AAG20341.1| (AE005107) pre-mRNA splicing helicase; Brr2 [Halobacterium sp.
NRC-1]
Length = 779
Score = 99.5 bits (244), Expect = 1e-19
Identities = 109/397 (27%), Positives = 164/397 (40%), Gaps = 65/397 (16%)
Query: 199 LDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKAL 258
+D+ E + + E +Q A+ + L N++ + T SGKT + ELA
Sbjct: 1 MDVAEVVPEFAEAFPFDEFNAMQREAVPALLESDANVVASAPTGSGKTALAELAICQTLA 60
Query: 259 NGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADII 318
+G LF+ PL AL N+K ED R+ LG V + G + R AD++
Sbjct: 61 DGGTALFVAPLRALTNEK-EDEWERFEALGYSVYVVTGERDLNPRRAE-------RADVL 112
Query: 319 VGTYEGIDYLLRAGKK-----IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQ 373
V T E D R + +V +VIDE+H+LD E RG L+ +++RLR+L +
Sbjct: 113 VMTPEKADSATRKHDSPRYAFVTDVECVVIDEVHLLDSETRGSVLEVVVSRLRRLC-DPR 171
Query: 374 FIGLSATIGNPEELAKALGMKLVLY-----DERPVDLERHLVIARNESEKW-----RLIA 423
+ LSAT+ N ++A L D RPVDL + + + RL
Sbjct: 172 VVALSATMPNIGDVADWLDATPDTTFEFDDDYRPVDLHAGVRTYDHGDNPFADKYRRLFT 231
Query: 424 KLCKVEAMRRSSKGFKGQTIVFTYSRRRC--------------------------HELAS 457
L E R GQ++VF SR+ H
Sbjct: 232 ALDLAEPHLRED----GQSLVFVASRQDTVQAAKKTRDEIAQRDIPVGSRGDYDFHTATE 287
Query: 458 FLTGKGLKAKP------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVI 511
L + L+ +H+GL + E F+ I V+ +T+ L GV+ PA V+
Sbjct: 288 ALDNETLRKSVLDGVAFHHAGLSTTDKSHVEQWFREGKIRVLFSTSTLAWGVNLPARCVV 347
Query: 512 FESLAM-----GNKWLSVREFHQMLGRAGRPLYHEKG 543
+ G +S + QMLGRAGRP Y + G
Sbjct: 348 IRDTKLHDPLEGEVDMSPLDVLQMLGRAGRPGYDDVG 384
>pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae)
>gi|1150588|emb|CAA64136.1| (X94357) ORF NRE1041;
EMBL:SC22156;U22156 [Saccharomyces cerevisiae]
>gi|1322927|emb|CAA96971.1| (Z72773) ORF YGL251c
[Saccharomyces cerevisiae]
Length = 1046
Score = 99.5 bits (244), Expect = 1e-19
Identities = 117/486 (24%), Positives = 210/486 (43%), Gaps = 78/486 (16%)
Query: 233 ENLLVVSATASGKTLIGELAGIP------KALNGKKMLFLVPLVALANQKYEDFRRRYSK 286
EN ++ S T SGKT++ ELA + N K++++ P +L + Y+++ +
Sbjct: 14 ENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKNWFPSF-- 71
Query: 287 LGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGN----VGTIV 342
V + VGM T + + +II+ T E D L R V ++
Sbjct: 72 ----VNLSVGMLTSDTSF--LETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVL 125
Query: 343 IDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELA------KALGMKLV 396
+DEIH + E+RG L+ ++ R+ + +F+ LSAT+ N E+LA L ++
Sbjct: 126 VDEIHTIK-EKRGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNNELPANIL 184
Query: 397 LYDE--RPVDLERHLV----IARNESEKW-----------------RLIAKLCKVEAMRR 433
+DE R V L + + +N+ +K R + C A
Sbjct: 185 SFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTI 244
Query: 434 SSKGFKGQTIVFTYSRRRCH-----ELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQ 488
S+ F +F+ S++RC+ ++ + +G+ +H+G+ + R E EF A
Sbjct: 245 STAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIAF--HHAGISLEDRTAVEKEFLAG 302
Query: 489 MIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFH-----QMLGRAGRPLYHEKG 543
I+++ +T+ L GV+ PA VI + N ++E+ QM+GRAGRP + G
Sbjct: 303 SINILCSTSTLAVGVNLPAYLVIIKGTKSWNS-SEIQEYSDLDVLQMIGRAGRPQFETHG 361
Query: 544 KVYLMVEPGRK--YSAQMEGT---EDEVALKLLTSPIEPVIVEWSDEIEED-NVLAHACV 597
+M + K Y + GT E + L L+ +E IE N L +
Sbjct: 362 CAVIMTDSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAVNWLRNTFF 421
Query: 598 FNRL----SVIEEVNSLT-------LGANRSAEKVLEKLEELGMVKLHGGIVRVTPYGRA 646
+ R + +EVN N+ + +L+ L ++ ++ + G + T YG A
Sbjct: 422 YVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVKVKIIDISNGEYKSTAYGNA 481
Query: 647 TSMSFL 652
+ ++
Sbjct: 482 MTRHYI 487
>sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22156) Hfm1p
[Saccharomyces cerevisiae]
Length = 1048
Score = 98.7 bits (242), Expect = 2e-19
Identities = 117/488 (23%), Positives = 210/488 (42%), Gaps = 80/488 (16%)
Query: 233 ENLLVVSATASGKTLIGELAGIP------KALNGKKMLFLVPLVALANQKYEDFRRRYSK 286
EN ++ S T SGKT++ ELA + N K++++ P +L + Y+++ +
Sbjct: 14 ENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKNWFPSF-- 71
Query: 287 LGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGN----VGTIV 342
V + VGM T + + +II+ T E D L R V ++
Sbjct: 72 ----VNLSVGMLTSDTSF--LETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVL 125
Query: 343 IDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELA------KALGMKLV 396
+DEIH + E+RG L+ ++ R+ + +F+ LSAT+ N E+LA L ++
Sbjct: 126 VDEIHTIK-EKRGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNNELPANIL 184
Query: 397 LYDE--RPVDLERHLV----IARNESEKW-----------------RLIAKLCKVEAMRR 433
+DE R V L + + +N+ +K R + C A
Sbjct: 185 SFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTI 244
Query: 434 SSKGFKGQTIVFTYSRRRCH-----ELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQ 488
S+ F +F+ S++RC+ ++ + +G+ +H+G+ + R E EF A
Sbjct: 245 STAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIAF--HHAGISLEDRTAVEKEFLAG 302
Query: 489 MIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFH-----QMLGRAGRPLYHEKG 543
I+++ +T+ L GV+ PA VI + N ++E+ QM+GRAGRP + G
Sbjct: 303 SINILCSTSTLAVGVNLPAYLVIIKGTKSWNS-SEIQEYSDLDVLQMIGRAGRPQFETHG 361
Query: 544 KVYLMVEPGRK--YSAQMEGT---EDEVALKLLTSPIEPVIVEWSDEIEED---NVLAHA 595
+M + K Y + GT E + L L+ +E IE N L +
Sbjct: 362 CAVIMTDSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAAAVNWLRNT 421
Query: 596 CVFNRL----SVIEEVNSLT-------LGANRSAEKVLEKLEELGMVKLHGGIVRVTPYG 644
+ R + +EVN N+ + +L+ L ++ ++ + G + T YG
Sbjct: 422 FFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVKVKIIDISNGEYKSTAYG 481
Query: 645 RATSMSFL 652
A + ++
Sbjct: 482 NAMTRHYI 489
>pir||T27149 hypothetical protein Y54E2A.6 - Caenorhabditis elegans
>gi|3881104|emb|CAA21682.1| (AL032646) contains
similarity to Pfam domain: PF00270 (DEAD/DEAH box
helicase), Score=243.2, E-value=1.9e-76, N=2~cDNA EST
CEMSC91F comes from this gene~cDNA EST yk36e11.3 comes
from this gene~cDNA EST yk42a9.3 comes from this
gene~cDNA EST yk42a9.5 c>
Length = 1798
Score = 97.9 bits (240), Expect = 4e-19
Identities = 122/446 (27%), Positives = 192/446 (42%), Gaps = 101/446 (22%)
Query: 176 PEITKWDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENL 235
P K D K + + V+ M DEL + FK KL I+ ++ Q K ENL
Sbjct: 61 PPSNKGDIEKIQHVYVKDM--DELG-QKGFKGFEKLNVIQSIVFEQAYKTK------ENL 111
Query: 236 LVVSATASGKTLIGELA---GIPKALNGK--------KMLFLVPLVALANQKYEDFRRRY 284
L+ + T +GKT I L I + N + K++++ P+ ALA + E F +R
Sbjct: 112 LICAPTGAGKTNIAMLTILNTIHEHQNSRGDIMKDDFKIIYIAPMKALATEMTESFGKRL 171
Query: 285 SKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK----IGNVGT 340
+ LGLKV G +++ E V DT ++V T E D + R I V
Sbjct: 172 APLGLKVKELTGDTQLSRNE---VADT----QMLVLTPEKWDVITRKSTSDNSLINVVRL 224
Query: 341 IVIDEIHMLDDEERGPRLDGLIAR-LRKL---YPGAQFIGLSATIGNPEELAKALGMK-- 394
++IDE+H+L D ERGP ++ L+AR LR++ G + +GLSAT+ N ++A+ L +
Sbjct: 225 LIIDEVHLLHD-ERGPVIETLVARTLRQVEMSQSGIRIVGLSATLPNFIDVARFLRVNPY 283
Query: 395 --LVLYDE--RPVDLERHLVIAR---NESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTY 447
L +D RPV L + + R N + L+ +C E + +G Q +VF +
Sbjct: 284 KGLFFFDGRFRPVPLTQKFIGTRKAGNFRDNLTLMDNVCYDEVVDFVKRGH--QVLVFVH 341
Query: 448 SRRRCHELAS--------------------------------------------FLTGKG 463
+R +L F G G
Sbjct: 342 TRNGTAKLGEAFCARASVLGQMDLFLPKDRASSKYIQADKAINICRNRAQISPLFQRGMG 401
Query: 464 LKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKW-- 521
+ +H+GL + R + E F + V+ TA L GV+ PA V+ + + +
Sbjct: 402 I----HHAGLCRQDRILMERCFAEGHVSVLFCTATLAWGVNLPAHAVVIKGTDVFDAEKG 457
Query: 522 ----LSVREFHQMLGRAGRPLYHEKG 543
L V + Q+ GRAGRP + +G
Sbjct: 458 VFTDLGVLDVQQIFGRAGRPQFENEG 483
>pir||C71004 probable ATP-dependent helicase - Pyrococcus horikoshii
>gi|3257752|dbj|BAA30435.1| (AP000006) 912aa long
hypothetical ATP-dependent helicase [Pyrococcus
horikoshii]
Length = 912
Score = 93.2 bits (228), Expect = 1e-17
Identities = 119/471 (25%), Positives = 206/471 (43%), Gaps = 66/471 (14%)
Query: 201 IPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNG 260
I EKF + KL Q+ A K+ EGE++L+++ T SGKT + I L
Sbjct: 9 IKEKFGKLNKL---------QIQAFKAIYGEGESVLIIAPTGSGKTEAAIIPVINSILKD 59
Query: 261 K----KMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDAD 316
L++ PL AL E + K G+KV +R G + R + V
Sbjct: 60 NLRPISCLYIAPLKALNRDLLERLKWWGEKTGIKVEVRHGDTPQSMRAKQV----KNPPH 115
Query: 317 IIVGTYEGIDYLLRA---GKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQ 373
I++ T E + +L K + NV +++DEI L D +RG + LI L++L A
Sbjct: 116 ILITTPESLPAILTTKSLRKYLENVKFVIVDEITELVDNKRGIQ---LILNLKRLSLIAD 172
Query: 374 F--IGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWRLIAKL------ 425
F IGLSAT+GN EE+ + K ++ + ++ + + E L KL
Sbjct: 173 FIRIGLSATVGNEEEIREWFEAKRIIKPHLKKRYKFKVLYPQPKPEDQELAEKLKVPGDV 232
Query: 426 -CKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEME 484
++ + + +K + ++F +R+ L L G + +H L + R E +
Sbjct: 233 ATRLRTLWEIVEKYK-KALIFVNTRQFAEILGHRLKTWGKPVEVHHGSLSKEARIEAERK 291
Query: 485 FQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH--EK 542
+ I ++ T+++ G+D V+ + ++S R+ ++++ RAGR + E
Sbjct: 292 LKEGKIKALICTSSMELGIDIGDVDVVIQ-------YMSPRQVNRLIQRAGRSRHRLWEV 344
Query: 543 GKVYL-----------MVEPGRKYSAQMEGTED-EVALKLLTSPIEPVIVEWSD-EIEED 589
+ Y+ +V R ++EG + E AL +L I +++E+ D +I E
Sbjct: 345 SEAYIITTGVEDYLQGLVIAKRALEGKLEGVKPYENALDVLAHFIVGLLIEYRDLKINEP 404
Query: 590 NVLAHACVFNRLSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVRV 640
LA R E+ +VLE LEE G++K H +R+
Sbjct: 405 YRLAKDTYPYRKLRWEDY-----------LRVLEILEEAGIIKRHEDRLRL 444
>pir||T39411 RNA helicase - fission yeast (Schizosaccharomyces pombe)
>gi|3080535|emb|CAA18663.1| (AL022600) DEAD box helicase
[Schizosaccharomyces pombe]
Length = 1935
Score = 87.8 bits (214), Expect = 5e-16
Identities = 97/405 (23%), Positives = 169/405 (40%), Gaps = 85/405 (20%)
Query: 220 VQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALN-------------------G 260
+Q L EN+L+ + T +GKT + LA + N
Sbjct: 281 IQSLVYPIAYKTNENMLICAPTGAGKTDVALLAMLQTISNYVESMNLMDESEPLDVHRDD 340
Query: 261 KKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVG---MSRIKTREEPVVVDTGIDADI 317
K++++ P+ ALA + E +R + LGLK G +++ + E ++V T D+
Sbjct: 341 FKIVYIAPMKALAAEVVEKMGKRLAWLGLKTRELTGDMQLTKTEIAETQILVTTPEKWDV 400
Query: 318 IVGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQ---- 373
+ G L V ++IDE+HML D ERG ++ L+AR ++L +Q
Sbjct: 401 VTRKSVGDTQLAE------KVRLVIIDEVHMLHD-ERGAVIESLVARTQRLVETSQQMIR 453
Query: 374 FIGLSATIGNPEELAKALGM---KLVLYDE---RPVDLERHLVIARNESEKWRL-IAKLC 426
+GLSAT+ N ++A LG+ K + Y RP +E+H + A+ + I + C
Sbjct: 454 IVGLSATLPNYLDVADFLGVNRYKGLFYFSSAFRPCPIEQHFIGAKGSPKIVNSNIDEAC 513
Query: 427 KVEAMRRSSKGFKGQTIVFTYSRRRC------------------------HELASFLTGK 462
+ ++ +G Q ++F +SR+ HE S
Sbjct: 514 FDKVLKLIQEGH--QVMIFVHSRKETINSAKKLREQFFHEGEADLLDNSQHEKYSLAQRD 571
Query: 463 GLKAKP-------------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQ 509
K+K +++G+ R +TE F ++ ++ TA L GV+ PA
Sbjct: 572 VSKSKNKELKELFKYSMGIHNAGMLRSDRHLTERLFSMGILKILCCTATLAWGVNLPAYA 631
Query: 510 VIFESLAMGNKW------LSVREFHQMLGRAGRPLYHEKGKVYLM 548
V+ + + + L V + Q+ GRAGRP + Y++
Sbjct: 632 VLIKGTQLYDPQKGSFVDLGVLDVLQIFGRAGRPQFESSAVAYII 676
>pir||T09159 RNA helicase prh75 - spinach >gi|1488647|emb|CAA68193.1| (X99937)
RNA helicase [Spinacia oleracea]
Length = 685
Score = 87.4 bits (213), Expect = 6e-16
Identities = 121/481 (25%), Positives = 204/481 (42%), Gaps = 80/481 (16%)
Query: 147 EQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITKWDELKAKRIKVERMTIDELDIPEKF- 205
E+ K+ K DLD D E+ + D+LK K+ KV + E + P
Sbjct: 57 EKEKKKKRKAVDLD------DSSDKSDNSSELVQADDLKPKKAKVMEEAVVEAEDPNSLS 110
Query: 206 --------KDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKA 257
KD+L +GIK L P+Q + + +++G +L+ + T GKTL L +
Sbjct: 111 NFRISKPLKDVLISKGIKALFPIQAMTFDN-VIDGCDLVGRARTGQGKTLAFVLPIVESL 169
Query: 258 LNGK-------------KMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTRE 304
+NG+ +L L+P LA Q DF+ +GL G + ++
Sbjct: 170 VNGRTKDLRRSGHGRLPSVLVLLPTRELATQVLADFQVYGGAVGLTACSVYGGAPFHSQI 229
Query: 305 EPVVVDTGIDADIIVGTYEGIDYLLRAGK-KIGNVGTIVIDE------IHMLDDEERGPR 357
+ G+D I+VGT + LL G K+G++ V+DE + +DD E
Sbjct: 230 SSLT--RGVD--IVVGTPGRVKDLLEKGVLKLGSLLFRVLDEADEMLKMGFVDDVEL--- 282
Query: 358 LDGLIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYDERPVDLE----------- 406
+ G + + K+ Q + SAT+ + K + + + ++ VDL
Sbjct: 283 ILGKVDHVSKV----QTLLFSATLPS---WVKQISTRFLKSAKKTVDLVSDQKMKASISV 335
Query: 407 RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKA 466
RH+VI + S + LI + + G G++I+FT ++ +LA LTG A
Sbjct: 336 RHIVIPCSASARPDLIPDIIRCY-------GSGGRSIIFTETKESASQLAGLLTG----A 384
Query: 467 KPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVRE 526
+P H + QR++T F+ +V T G+D Q+I + V +
Sbjct: 385 RPLHGDIQQTQREVTLKGFRTGKFMTLVATNVAARGLDINDVQLIIQC----EPPRDVED 440
Query: 527 FHQMLGRAGRPLYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVEWSDEI 586
+ GR GR G ++ +P R ++E E V + L++P +PV V + I
Sbjct: 441 YIHRSGRTGRA--GNTGVAVMLYDPKRSSVTKIE-RESGVKFEHLSAP-QPVDVAKAVGI 496
Query: 587 E 587
E
Sbjct: 497 E 497
>dbj|BAA34508.1| (AB018331) KIAA0788 protein [Homo sapiens]
Length = 1324
Score = 87.4 bits (213), Expect = 6e-16
Identities = 98/392 (25%), Positives = 169/392 (43%), Gaps = 66/392 (16%)
Query: 219 PVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGK--KMLFLVPLVALANQK 276
P+Q + +N+ V + T SGKT+ E A + L + +++ P+ ALA Q
Sbjct: 518 PIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQV 577
Query: 277 YEDFRRRY-SKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK- 334
Y D+ ++ +L KV + G +T + ++ G +II+ T E D L R K+
Sbjct: 578 YMDWYEKFQDRLNKKVVLLTG----ETSTDLKLLGKG---NIIISTPEKWDILSRRWKQR 630
Query: 335 --IGNVGTIVIDEIHMLDDEERGPRLDGLIARLR----KLYPGAQFIGLSATIGNPEELA 388
+ N+ V+DE+H++ E GP L+ + +R+R ++ + + LS+++ N +++A
Sbjct: 631 KNVQNINLFVVDEVHLIGG-ENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVA 689
Query: 389 KALGMKLVLY-----DERPVDLERHLVIARNESEKWRLIAKLCKV-EAMRRSSKGFKGQT 442
LG + RPV LE H+ + RL++ V A+ + S K
Sbjct: 690 HWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSP--KKPV 747
Query: 443 IVFTYSRRRCHELA--------------SFLTGKGLKAKPY------------------- 469
IVF SR++ A FL PY
Sbjct: 748 IVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGY 807
Query: 470 -HSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWL------ 522
H GL +R++ E F + I VVV + +L G++ A VI N +
Sbjct: 808 LHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDY 867
Query: 523 SVREFHQMLGRAGRPLYHEKGKVYLMVEPGRK 554
+ + QM+G A RPL ++G+ +M + +K
Sbjct: 868 PIYDVLQMVGHANRPLQDDEGRCVIMCQGSKK 899
>pir||S76892 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1653894|dbj|BAA18804.1| (D90917) antiviral protein
[Synechocystis sp.]
Length = 1006
Score = 86.6 bits (211), Expect = 1e-15
Identities = 57/168 (33%), Positives = 88/168 (51%), Gaps = 13/168 (7%)
Query: 227 SGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSK 286
+ L + ++++V + T SGKT++GE A GK++ + PL AL+NQK DF+ + K
Sbjct: 26 AALDQDQSVVVCAPTGSGKTVVGEYAIYRAIARGKRVFYTTPLKALSNQKIRDFQEKLEK 85
Query: 287 LGLK-----VAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTI 341
LGL+ V + G + I VV+ T I +++ T G G + +V T+
Sbjct: 86 LGLENAAQLVGLITGDTVINADAPVVVMTTEIFRNMLYETPIG-----EVGTSLEDVETV 140
Query: 342 VIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAK 389
V DE+H + D RG + I Q +GLSATIGNPE+L +
Sbjct: 141 VFDEVHYISDRGRGTVWEESIIYCPST---IQLVGLSATIGNPEQLTE 185
>pir||A69140 ATP-dependent helicase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621366|gb|AAB84818.1| (AE000816)
ATP-dependent helicase [Methanobacterium
thermoautotrophicum]
Length = 702
Score = 86.6 bits (211), Expect = 1e-15
Identities = 100/341 (29%), Positives = 156/341 (45%), Gaps = 43/341 (12%)
Query: 213 GIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIP-------KALNGKKMLF 265
G + L VQ A+++ + GE+ L+V+ TASGKT E A IP + L ML+
Sbjct: 19 GWRSLRDVQKSALEA-IGRGEDTLIVAPTASGKT---EAALIPVFNSILSEGLPPVSMLY 74
Query: 266 LVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGI 325
+ PL AL N + + L+V G + + + DI++ T E +
Sbjct: 75 VSPLKALINDMHSRLELWGNHFNLEVMKWHGDVPANRKRRFIKNPS----DILLITPESL 130
Query: 326 DYLL----RAGKK--IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGA--QFIGL 377
+ ++ RA K+ +GN+ I++DEIH + +RG +L+ L+ARL + Y G Q IGL
Sbjct: 131 EVMMINRSRAEKERILGNLRYIIVDEIHQFIEADRGVQLNSLLARLER-YTGVRPQRIGL 189
Query: 378 SATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAMRRSSKG 437
SAT+GNPEE+ + + + ER L E +LI E +RR
Sbjct: 190 SATVGNPEEVLNWMSPSGAVVRD---TAERKLQYRIFELNHHKLI------EVLRR---- 236
Query: 438 FKGQTIVFTYSRRRCHELASFLTGKGLKAKPY--HSGLPYKQRKITEMEFQAQMIDVVVT 495
F G+ ++ RR E + K L + HS + R+ E F++ +V
Sbjct: 237 FTGKKVLIFVPSRRDAEKYYNIIRKCLDVDVFIHHSSINRDSREEAEERFRSVSAAFMVN 296
Query: 496 TAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
T+ L G+D V+ + SV F Q GR+GR
Sbjct: 297 TSTLELGIDVGDIDVVIHIRSP----TSVNRFLQRTGRSGR 333
>emb|CAB59484.1| (AL132648) putative helicase [Streptomyces coelicolor A3(2)]
Length = 950
Score = 86.6 bits (211), Expect = 1e-15
Identities = 63/201 (31%), Positives = 103/201 (50%), Gaps = 23/201 (11%)
Query: 219 PVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYE 278
P Q+ A ++ L G+ +LV + T SGKT++GE A G+K + P+ AL+NQKY
Sbjct: 53 PFQIEACQA-LEAGKGVLVAAPTGSGKTIVGEFAVHLALQQGRKCFYTTPIKALSNQKYA 111
Query: 279 DFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK-IGN 337
D RRY KV + G + + + +A ++V T E + +L AG + +
Sbjct: 112 DLCRRYGT--DKVGLLTGDNSVNS-----------EAPVVVMTTEVLRNMLYAGSQTLLG 158
Query: 338 VGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKAL-----G 392
+G +V+DE+H L D RG + +I L + + LSAT+ N EE L
Sbjct: 159 LGHVVMDEVHYLSDRFRGAVWEEVIIHLPE---SVTLVSLSATVSNAEEFGDWLDTVRGD 215
Query: 393 MKLVLYDERPVDLERHLVIAR 413
++++ + RPV L +H++ R
Sbjct: 216 TQVIVSEHRPVPLFQHVLAGR 236
>emb|CAC11967.1| (AL445065) Large helicase related protein [Thermoplasma
acidophilum]
Length = 894
Score = 86.2 bits (210), Expect = 1e-15
Identities = 88/329 (26%), Positives = 150/329 (44%), Gaps = 37/329 (11%)
Query: 229 LLEGENLLVVSATASGKTLIGELAGIPKALNGKKM----LFLVPLVALANQKYEDFRRRY 284
+LEG+N+L++S T SGKT L + L K L++ PL AL
Sbjct: 35 VLEGKNVLLLSPTGSGKTEAAVLPVFQRILREKPKKVFALYITPLRALNRDILSRLVDYG 94
Query: 285 SKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK----IGNVGT 340
+LG+ V +R S + ++ + ++ DI+V T E + LL GK I NV
Sbjct: 95 RELGIDVQVR--HSDMSDADKRRMAES--PPDILVTTPESLQILLN-GKNLRRFIANVRV 149
Query: 341 IVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKAL---GMKLVL 397
+++DE+H + ERG +L + RLR L Q IGLSAT+GNP +LA+ L G ++
Sbjct: 150 VIVDELHDAAENERGSQLSLALERLRDLAGNFQRIGLSATVGNPGDLARFLVPNGTCEII 209
Query: 398 YDERPVDLERHLVIARNESEK--------WRLIAKLCKVEAMRRSSKGFKGQTIVFTYSR 449
++ +++ SE+ + + KV + G ++VF R
Sbjct: 210 STTLKKNMSIDVMVPDESSEEDAEVMGCDRQYAGAILKVWDLINRHAG----SLVFVNRR 265
Query: 450 RRCHELASFLTGK--GLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPA 507
+LA L K + +H L + R+ E F+ + ++ T++L G+D
Sbjct: 266 FVAEDLAFRLKLKFGEIPVLVHHGSLSKETREFAERSFKNGEVKALICTSSLELGIDVGT 325
Query: 508 SQVIFESLAMGNKWLSVREFHQMLGRAGR 536
+ + + + S R+ ++M+ R GR
Sbjct: 326 ANAVIQ-------FNSPRQINKMIQRIGR 347
>gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobus fulgidus]
>gi|7446074|pir||D69393 large helicase-related protein
(lhr-1) homolog - Archaeoglobus fulgidus
>gi|2649437|gb|AAB90094.1| (AE001024) large
helicase-related protein (lhr-1) [Archaeoglobus
fulgidus]
Length = 892
Score = 85.8 bits (209), Expect = 2e-15
Identities = 90/352 (25%), Positives = 162/352 (45%), Gaps = 38/352 (10%)
Query: 203 EKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIP------- 255
++ ++ L GI+EL +Q+ A + +L G+++L+++ T SGKT E A IP
Sbjct: 4 QRLREALSAAGIEELTELQLEAFRK-ILSGKDVLIIAPTGSGKT---EAAIIPIFEAMLK 59
Query: 256 -KALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGID 314
+ G +++ PL AL R LG++V +R G T + +
Sbjct: 60 MEKPEGIVAIYITPLRALNRDMLRRIRGIAEFLGIRVDVRHG----DTPDSQRARQSRKP 115
Query: 315 ADIIVGTYEGIDYLL---RAGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPG 371
+++ T E L K + NV +V+DEIH L D ERG +L + RLR++
Sbjct: 116 PHLLITTPETFQILFLGKNLRKALKNVRYVVVDEIHELIDSERGVQLSVALERLREM-AR 174
Query: 372 AQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAM 431
Q IGLSAT+ P+ +++ +G + E + E + + + E ++ +L AKL V+A
Sbjct: 175 FQTIGLSATVSRPKLVSRFVGADAEVL-EWKAEKEYEIEVVKPEVDE-KLAAKL-GVDAE 231
Query: 432 RRSSKGF-------KGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEME 484
F G ++F +R+ L L K + + +H L + R E
Sbjct: 232 IAGELKFIADAVKEHGSALIFVNTRQTAEALGIKLK-KLIDVEVHHGSLSRETRVEAEER 290
Query: 485 FQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
F +D ++ T+++ G+D ++ + + S R+ +++ R GR
Sbjct: 291 FAKGELDALICTSSMELGIDIGHVNLVVQ-------YNSPRQAVRLVQRVGR 335
>dbj|BAB02697.1| (AB018114) helicase-like protein [Arabidopsis thaliana]
Length = 1111
Score = 85.4 bits (208), Expect = 2e-15
Identities = 106/384 (27%), Positives = 172/384 (44%), Gaps = 52/384 (13%)
Query: 234 NLLVVSATASGKTLIGELAGI---PKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLK 290
N+++ + T SGKT++ EL + K+++ K+ FL AL +K D+ ++++ G+
Sbjct: 42 NMIISAPTGSGKTVLFELCILRLFSKSIS-KEGSFLHAKGALKTEKLRDWNQKFNSWGIS 100
Query: 291 VAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVG------TIVID 344
G + + + DADII+ T E D + R G +G ++ID
Sbjct: 101 CLELTGDNETYSTKNIQ------DADIILTTPEKFDAVSRYRVTSGGLGFFSDIALVLID 154
Query: 345 EIHMLDDEERGPRLDGLIARLRKL----------YPGAQFIGLSATIGNPEELAKAL--- 391
E+H+L+D RG L+ +++RL+ L + + +SATI N E+LA+ L
Sbjct: 155 EVHLLNDP-RGAALEAIVSRLKILSSNHELRSSTLASVRLLAVSATIPNIEDLAEWLKVP 213
Query: 392 --GMKLVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSR 449
G+K + RPV L + LI+K+ + M S K + + +
Sbjct: 214 TAGIKRFGEEMRPVKLTTKVFGTG-------LISKVMLLPRMTSSLKREQLERLREASPM 266
Query: 450 RRCHELASFLTGKGLKAKP---YHSG-LPYKQRKITEMEFQAQMIDVVVTTAALGAGVDF 505
++ S++ K YH+G L K R + E F I V+ TT L G++
Sbjct: 267 CSDKQMQSYILQGVTKMSQLVGYHNGGLCQKDRSLVEGLFLNGDIQVICTTNTLAHGINL 326
Query: 506 PASQVIFESLAMGNKWLS-VREFH-----QMLGRAGRPLYHEKGKVYLMV--EPGRKYSA 557
PA V+ +S NK E+ QM GRAGRP + + G V +M E Y
Sbjct: 327 PAHTVVIKSTQHFNKEKGHYMEYDRSTLLQMSGRAGRPPFDDTGMVIIMTRRETVHLYEN 386
Query: 558 QMEGTEDEVALKLLTSPIEPVIVE 581
+ G E V +LL IE + E
Sbjct: 387 LLNGCE-VVESQLLPCLIEHLTAE 409
>emb|CAA11251.1| (AJ223310) helicase [Streptomyces avermitilis]
>gi|4098452|gb|AAD00270.1| (U77894) helicase-like
protein [Streptomyces avermitilis]
Length = 612
Score = 84.7 bits (206), Expect = 4e-15
Identities = 62/193 (32%), Positives = 95/193 (49%), Gaps = 22/193 (11%)
Query: 227 SGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSK 286
SG G+ AT SGKT++GE A GKK + P+ AL+NQKY D RRY
Sbjct: 44 SGTRGGQGGAGGRATGSGKTIVGEFAVHLALQQGKKCFYTTPIKALSNQKYADLARRYG- 102
Query: 287 LGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK-IGNVGTIVIDE 345
KV + G + + + DA ++V T E + +L AG + + +G +V+DE
Sbjct: 103 -ADKVGLLTGDNSVNS-----------DAPVVVMTTEVLRNMLYAGSQTLLGLGYVVMDE 150
Query: 346 IHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKAL-----GMKLVLYDE 400
+H L D RG + +I L + + LSAT+ N EE L ++++ +
Sbjct: 151 VHYLSDRFRGAVWEEVIIHLPE---SVTLVSLSATVSNAEEFGDWLDTVRGDTQVIVSEH 207
Query: 401 RPVDLERHLVIAR 413
RPV L +H++ R
Sbjct: 208 RPVPLFQHVLAGR 220
>pir||T35049 probable ATP-dependent helicase - Streptomyces coelicolor
>gi|3483040|emb|CAA20551.1| (AL031371) putative
ATP-dependent helicase [Streptomyces coelicolor A3(2)]
Length = 731
Score = 82.7 bits (201), Expect = 2e-14
Identities = 98/375 (26%), Positives = 163/375 (43%), Gaps = 52/375 (13%)
Query: 196 IDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIP 255
+D LD P I+ G +L P+Q AI + L+EGE+ ++++ TA GKT E A P
Sbjct: 16 LDRLD-PVVLHHIVNTLGWSDLRPLQRAAI-TPLMEGEDAVLLAPTAGGKT---EAACFP 70
Query: 256 -------KALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVV 308
+ G +L+L PL AL N LG + A+ G ++ R+
Sbjct: 71 LLSAMAEQKWTGTSVLYLCPLKALLNNLVSRVDTYTQWLGRRAALWHGDTKESQRQR--- 127
Query: 309 VDTGIDADIIVGTYEGIDYLLRAGKK-----IGNVGTIVIDEIHMLDDEERGPRLDGLIA 363
+ T D+++ T E ++ +L K +G+V +V+DE+H ++RG L ++
Sbjct: 128 IRTEAP-DVLLTTPESLEAMLIGVKTDHARLLGSVRAVVVDEVHAFAGDDRGWHLLAVLE 186
Query: 364 RLRKLY-PGAQFIGLSATIGNPEEL---------------AKALGMKLVLY-----DERP 402
RL ++ Q IGLSAT+GNP++L A G+ L + D +P
Sbjct: 187 RLEQVTGRPIQRIGLSATVGNPDQLLDWLQGAGVETRAGRVVAPGVTLPAFEAVGSDRKP 246
Query: 403 VDLERHLVIARNESEKWRLIAKLCK-VEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTG 461
E E + + K + + R K +VF SR + +L + L
Sbjct: 247 TAEEVPRPAGEVELDYVGSLDNAAKLIATLHRGEK-----RLVFCDSRAQVEQLGAALRA 301
Query: 462 KGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKW 521
+ + H+ L +R +E F V+V+T+ L G+D + + +
Sbjct: 302 REVTVFLSHASLSVDERTRSEQAFAEARDCVIVSTSTLELGIDVGDLDRVIQI----DSP 357
Query: 522 LSVREFHQMLGRAGR 536
+V F Q +GR GR
Sbjct: 358 ATVASFLQRIGRTGR 372
>gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 739
Score = 81.9 bits (199), Expect = 3e-14
Identities = 94/395 (23%), Positives = 169/395 (41%), Gaps = 27/395 (6%)
Query: 195 TIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGI 254
+I+E+DI +K K + GI+ L Q A + + EN++++S T +GKT + +
Sbjct: 34 SINEIDIDDKLKKSIIEYGIERLYKYQYDAYRK-IKNKENVMIISGTGTGKTEAFLIPIL 92
Query: 255 PKALNGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREE-----PVVV 309
AL G++ + + P ALA + + +LGL V I G + K RE P ++
Sbjct: 93 DLALKGERSVLVYPTKALARDQLTRVYKLARELGLNVGIFDGDTPEKERERLYRNPPHIL 152
Query: 310 DTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLY 369
T D + G+ R + + DE+H+ + G + L R+++
Sbjct: 153 ITNPDM-----IHLGLALSTRFRFLLRTADHFIFDEVHVYEG-VLGAHIRNLADRIKEFK 206
Query: 370 PGAQFIGLSATIGNPEELAKAL-GMKLVLYD--ERPVDLERHLVIARNESEKWRLIAKLC 426
+ SAT+G + L + L G++ + + R + H +I S +W L A L
Sbjct: 207 NDIHIVASSATVGATKYLFEELFGVEGEIIEGIRRRKGIAIHSIIDSGNSSRWTLAAYLA 266
Query: 427 KVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQ 486
V G K +VFT S++ +A + + + +GL ++R E + +
Sbjct: 267 AVLV----KNGLK--VLVFTDSQQMAELVAKIADRFRVNLEVHRAGLIAEERIKVEEKLR 320
Query: 487 AQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYHEKGKVY 546
+D VV T L G+D +++ M S ++ Q GRAGR + G V+
Sbjct: 321 NGELDGVVATPTLELGIDIGT----IDAVIMAENPPSYTKYVQRAGRAGR--RNNAGLVF 374
Query: 547 LMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIVE 581
++ S + E+ K+ +P +E
Sbjct: 375 TILGDDPIDSYYLRHPEEFFTRKIQALTFDPTNIE 409
>pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyrococcus abyssi
(strain Orsay) >gi|5458242|emb|CAB49731.1| (AJ248285)
large helicase-related protein (lhr-1) [Pyrococcus
abyssi]
Length = 912
Score = 80.4 bits (195), Expect = 8e-14
Identities = 89/348 (25%), Positives = 156/348 (44%), Gaps = 46/348 (13%)
Query: 212 EGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGK----KMLFLV 267
E +EL +Q+ A K + EG+++L+++ T SGKT L + L L++
Sbjct: 11 EKFRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIA 69
Query: 268 PLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDY 327
PL AL E + +K G+++ +R G + R + V +++ T E +
Sbjct: 70 PLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQV----RNPPHVLITTPETLPA 125
Query: 328 LLRAGKK---IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFI--GLSATIG 382
LL + NV +V+DE+ L D +RG +L I L++L A FI GLSAT+G
Sbjct: 126 LLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQL---ILNLKRLSLIADFIRIGLSATVG 182
Query: 383 NPEELAKALGM--------------KLVLYDERPVDLERHLVIARNESEKWRLIAKLCKV 428
N EE+ + LG+ K++ RP D E ++ + RL V
Sbjct: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIV 242
Query: 429 EAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQ 488
E +R +VF +R+ LA L G + +H L + R E + +
Sbjct: 243 EKHKR--------VLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEG 294
Query: 489 MIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
+ ++ T+++ G+D + + ++S R+ ++++ RAGR
Sbjct: 295 KVKALICTSSMELGIDIGEVDAVIQ-------YMSPRQVNRLIQRAGR 335
>pir||T20430 hypothetical protein E03A3.2 - Caenorhabditis elegans
>gi|3875424|emb|CAA86232.1| (Z38112) contains similarity
to Pfam domain: PF00270 (DEAD/DEAH box helicase),
Score=109.8, E-value=2.8e-34, N=1; PF00271 (Helicases
conserved C-terminal domain), Score=81.1,
E-value=7.4e-21, N=1~cDNA EST yk146e7.5 comes from this
gene [Caenorhabditis >
Length = 809
Score = 78.4 bits (190), Expect = 3e-13
Identities = 96/388 (24%), Positives = 156/388 (39%), Gaps = 55/388 (14%)
Query: 220 VQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYED 279
+Q+ AI L ++ V T +GK+L +L P ++G + + PL+AL +
Sbjct: 182 LQMQAINCILKRKCDVYVSLPTGAGKSLCYQL---PAVVHGGITVVISPLIALMKDQISS 238
Query: 280 FRRRYSKLGL--KVAIRVGMSRIK---TREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK 334
+R+ V SRI +E+P + + A+ + +G LL
Sbjct: 239 LKRKGIPCETLNSTLTTVERSRIMGELAKEKPTIRMLYLTAEGVAT--DGTKKLLNGLAN 296
Query: 335 IGNVGTIVIDEIHMLDDEERGPRLDGL-IARLRKLYPGAQFIGLSAT------------- 380
+ IV+DE H + R D L + LR + PG ++ L+AT
Sbjct: 297 RDVLRYIVVDEAHCVTQWGHDFRPDYLTLGSLRDVCPGVPWVALTATANAKAQDDIAFQL 356
Query: 381 -IGNPEELAKALGMKLVLYDERPVD-LERHLVIARNESEKWRLIAKLCKVEAMRRSS--K 436
+ NPE + YD + + L + S + L K E RS K
Sbjct: 357 KLRNPESFKSGTYRDNLFYDNHMASFITKCLTVDAKTSS-----SNLTKHEKAERSQNKK 411
Query: 437 GFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTT 496
F G IV+ SR C ++A L G+ A YH+GL K R + ++ I VV T
Sbjct: 412 TFTGSAIVYCRSRNECGQVAKMLEIAGIPAMAYHAGLGKKDRNEVQEKWMNNEIPVVAAT 471
Query: 497 AALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRP-------LYHEK------- 542
A G G+D P + + N + ++Q GRAGR +Y+ K
Sbjct: 472 VAFGMGIDKPDVRAVIHWSPSQN----LAGYYQEAGRAGRDGKRSYCRIYYSKQDKNALN 527
Query: 543 ----GKVYLMVEPGRKYSAQMEGTEDEV 566
G++ + E +K +A+ E E ++
Sbjct: 528 FLVSGELAKLREKAKKNNAEGEKAEMQI 555
>gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 933
Score = 76.5 bits (185), Expect = 1e-12
Identities = 121/492 (24%), Positives = 215/492 (43%), Gaps = 67/492 (13%)
Query: 196 IDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIP 255
+D LD ++ + +++ + +L VQ ++ + + G N LV++ T GKT L +
Sbjct: 2 LDHLD--QRLRKLIEEKNWMKLTRVQEMSFEP-ISNGYNTLVIAPTGYGKTEAALLPILN 58
Query: 256 KALNGK----KMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDT 311
+ L ++++ PL AL N S+LG V + G + +E+ + +
Sbjct: 59 RMLKEDVKPVTVIYITPLKALINDLLYRIDWWASRLGFLVNRKHG--EVPQKEKNLRLKR 116
Query: 312 GIDADIIVGTYEGI----DYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRK 367
IIV T EG+ D+ R + NV +V+DEIH L + +RG +L L+ RL K
Sbjct: 117 --IPHIIVTTPEGLEIDLDWASRFREHYKNVKWVVVDEIHELINSKRGTQLSILLERL-K 173
Query: 368 LYPGAQF--IGLSATIGNPEELAKAL------GMKLV-LYDERPVDLERHLVIARNESEK 418
+ G F IGLSAT+ + +++A+ L MK++ L D R +++ + + N
Sbjct: 174 YFIGYDFQRIGLSATVSDEDKVAQFLFGSSERKMKIIRLNDTRNFEIKINKLGNDNSFAL 233
Query: 419 WRLIAKLCKVEAMRRSSKGFKGQTIVFTYSR---RRCHELASFLTGKGLKAKPYHSGLPY 475
W+ A + ++ + T+VFT SR R HE L K + +HS +
Sbjct: 234 WK--------SAAEKINQLIEKPTLVFTNSRFSTERLHEELEKLGNKEIYV--HHSSVSR 283
Query: 476 KQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAG 535
+ + E E + VV T L G+ + + M SV F Q LGR+G
Sbjct: 284 DLKNLAEGELRNGNAKAVVCTKTLELGIHVGD----IKKVIMLRPPTSVSSFLQRLGRSG 339
Query: 536 RPLYH-EKGKV--------------YLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVIV 580
++ KG++ YL + G+ ++ D VA ++ + ++
Sbjct: 340 HIVHGVPKGEIICFYDFDVLESLALYLSAKDGKMEKPFIDDGLDVVAREI----VGMILQ 395
Query: 581 EWSDEIEE-DNVLAHACVFNRLSVIEEVNSLTLGANRSAEKVLEKLEELGMVKLHGGIVR 639
IEE N++ ++ L E++ L N + + K+EE +KL G +
Sbjct: 396 NQKMSIEEIFNIIRGTYIYRNL----ELSKLLDLVNYLVKNNIIKIEE-NYLKLGQGFFK 450
Query: 640 VTPYGRATSMSF 651
+ + R S+
Sbjct: 451 IWRFNRDAKNSW 462
>emb|CAA22943.1| (AL035310) putative helicase [Mycobacterium leprae]
Length = 920
Score = 76.5 bits (185), Expect = 1e-12
Identities = 60/193 (31%), Positives = 96/193 (49%), Gaps = 22/193 (11%)
Query: 227 SGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSK 286
+ L G +LV + T +GKT++GE A G K + PL AL+NQKY D RY +
Sbjct: 27 AALERGHGVLVCAPTGAGKTVVGEFAVHLALAAGGKCFYTTPLKALSNQKYTDLTARYGR 86
Query: 287 LGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGK-KIGNVGTIVIDE 345
R+G + T ++ V D+ ++V T E + +L A + + +V+DE
Sbjct: 87 ------NRIG---LLTGDQSV----NGDSPVVVMTTEVLRNMLYADSFALQGLSHVVMDE 133
Query: 346 IHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEE----LAKALGMKLVLYDE- 400
+H + D RGP + +I L + + LSAT+ N EE + G V+ DE
Sbjct: 134 VHFIADRMRGPVWEEVILHLP---DDVRMVSLSATVSNAEEFGGWVQTVRGDTTVVVDEH 190
Query: 401 RPVDLERHLVIAR 413
RPV L +H+++ +
Sbjct: 191 RPVPLWQHVLVGK 203
>gb|AAA24517.1| (M30198) recQ [Escherichia coli]
Length = 610
Score = 75.3 bits (182), Expect = 3e-12
Identities = 81/333 (24%), Positives = 150/333 (44%), Gaps = 34/333 (10%)
Query: 213 GIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVAL 272
G ++ P Q I + +L G + LVV T GK+L ++ + LNG ++ + PL++L
Sbjct: 24 GYQQFRPGQEEIIDT-VLSGRDCLVVMPTGGGKSLCYQIPAL--LLNGLTVV-VSPLISL 79
Query: 273 ANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAG 332
+ + + G+ A ++ +TRE+ + V TG I Y + L+
Sbjct: 80 MKDQVDQLQAN----GVAAAC---LNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDN 132
Query: 333 ----KKIGNVGTIVIDEIHMLDDEERGPRLD-GLIARLRKLYPGAQFIGLSATIGNP--E 385
N + +DE H + R + + +LR+ +P F+ L+AT + +
Sbjct: 133 FLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDTTRQ 192
Query: 386 ELAKALGMKLVLYDERPVDLE--RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTI 443
++ + LG+ L D R++++ EK++ + +L + +R G I
Sbjct: 193 DIVRLLGLNDPLIQISSFDRPNIRYMLM-----EKFKPLDQLMRYVQEQRGKSG-----I 242
Query: 444 VFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGV 503
++ SR + + A+ L KG+ A YH+GL R + +FQ + +VV T A G G+
Sbjct: 243 IYCNSRAKVEDTAAALQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGI 302
Query: 504 DFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
+ P + + N + ++Q GRAGR
Sbjct: 303 NKPNVRFVVHFDIPRN----IESYYQETGRAGR 331
>gb|AAA67618.1| (M87049) DNA-dependent ATPase, DNA helicase [Escherichia coli]
Length = 610
Score = 75.3 bits (182), Expect = 3e-12
Identities = 81/333 (24%), Positives = 150/333 (44%), Gaps = 34/333 (10%)
Query: 213 GIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVAL 272
G ++ P Q I + +L G + LVV T GK+L ++ + LNG ++ + PL++L
Sbjct: 24 GYQQFRPGQEEIIDT-VLSGRDCLVVMPTGGGKSLCYQIPAL--LLNGLTVV-VSPLISL 79
Query: 273 ANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAG 332
+ + + G+ A ++ +TRE+ + V TG I Y + L+
Sbjct: 80 MKDQVDQLQAN----GVAAAC---LNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDN 132
Query: 333 ----KKIGNVGTIVIDEIHMLDDEERGPRLD-GLIARLRKLYPGAQFIGLSATIGNP--E 385
N + +DE H + R + + +LR+ +P F+ L+AT + +
Sbjct: 133 FLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDTTRQ 192
Query: 386 ELAKALGMKLVLYDERPVDLE--RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTI 443
++ + LG+ L D R++++ EK++ + +L + +R G I
Sbjct: 193 DIVRLLGLNDPLIQISSFDRPNIRYMLM-----EKFKPLDQLMRYVQEQRGKSG-----I 242
Query: 444 VFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGV 503
++ SR + + A+ L KG+ A YH+GL R + +FQ + +VV T A G G+
Sbjct: 243 IYCNSRAKVEDTAAALQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGI 302
Query: 504 DFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
+ P + + N + ++Q GRAGR
Sbjct: 303 NKPNVRFVVHFDIPRN----IESYYQETGRAGR 331
>sp|Q10701|HELY_MYCTU PUTATIVE HELICASE HELY >gi|7478108|pir||G70767 probable helicase
helY - Mycobacterium tuberculosis (strain H37RV)
>gi|1370259|emb|CAA98204.1| (Z73966) helY [Mycobacterium
tuberculosis]
Length = 906
Score = 75.3 bits (182), Expect = 3e-12
Identities = 57/195 (29%), Positives = 93/195 (47%), Gaps = 26/195 (13%)
Query: 227 SGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRYSK 286
S L G +LV + T +GKT++GE A G K + PL AL+NQK+ D RY +
Sbjct: 27 SALERGHGVLVCAPTGAGKTVVGEFAVHLALAAGSKCFYTTPLKALSNQKHTDLTARYGR 86
Query: 287 LGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVG---TYEGIDYLLRAGKKIGNVGTIVI 343
++ + G + VV+ T + +++ +G+ Y +V+
Sbjct: 87 --DQIGLLTGDLSVNGNAPVVVMTTEVLRNMLYADSPALQGLSY-------------VVM 131
Query: 344 DEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEE----LAKALGMKLVLYD 399
DE+H L D RGP + +I +L + + LSAT+ N EE + G V+ D
Sbjct: 132 DEVHFLADRMRGPVWEEVILQLP---DDVRVVSLSATVSNAEEFGGWIQTVRGDTTVVVD 188
Query: 400 E-RPVDLERHLVIAR 413
E RPV L +H+++ +
Sbjct: 189 EHRPVPLWQHVLVGK 203
>sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|2129094|pir||G64336
large helicase related protein LHR homolog -
Methanococcus jannaschii >gi|1591016|gb|AAB98279.1|
(U67484) large helicase-related protein (LHR), probably
RNA helicase [Methanococcus jannaschii]
Length = 841
Score = 75.3 bits (182), Expect = 3e-12
Identities = 99/365 (27%), Positives = 165/365 (45%), Gaps = 53/365 (14%)
Query: 215 KELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKK---------MLF 265
K P Q AIK + EG+N+L+ S T SGKTL LAGI + + +L+
Sbjct: 33 KTFTPPQRYAIKE-IHEGKNVLICSPTGSGKTLSAFLAGINELIKLSMENKLEDRIYILY 91
Query: 266 LVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGID---------AD 316
+ PL AL N + + ++ VA +G+ + R DT
Sbjct: 92 VSPLRALNNDIERNLKEPLKEI-YDVAKEIGIELDEIRVAVRTSDTTSSQKQRMLKKPPH 150
Query: 317 IIVGTYEGIDYLLRAGK---KIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQ 373
I++ T E + L + K + + +++DEIH L + +RG L + RL ++ A
Sbjct: 151 ILITTPESLAIALNSPKFSQLLSGIKYVIVDEIHALTN-KRGVHLSLSLERLNRI---AN 206
Query: 374 F--IGLSATIGNPEELAKAL---GMKLVLYD---ERPVDLE-----RHLVIARNESEKWR 420
F IGLSATI E+AK L G + D ++ ++++ + +E R
Sbjct: 207 FIRIGLSATIHPLTEVAKFLVGNGRDCYIVDVSYKKEIEIKVISPVDDFIYTPSEEISKR 266
Query: 421 LIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGL-KAKPYHSGLPYKQRK 479
L L K+ ++ T++FT +R +A +L G+ K + +HS L + R
Sbjct: 267 LYNLLKKLIEEHKT-------TLIFTNTRSATERVAFYLKQLGVEKVETHHSSLSREHRL 319
Query: 480 ITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLY 539
E + + I V +++ +L GVD + ++ + +G+ SV Q +GR+G L
Sbjct: 320 EVEEKLKKGEIRVCISSTSLELGVDIGSIDLV---ILLGSP-KSVSRALQRIGRSGHRL- 374
Query: 540 HEKGK 544
HEK K
Sbjct: 375 HEKSK 379
>gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobus fulgidus]
Length = 862
Score = 75.3 bits (182), Expect = 3e-12
Identities = 102/372 (27%), Positives = 162/372 (43%), Gaps = 60/372 (16%)
Query: 211 LEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIP----KALNGKK---- 262
L E P Q AI +G N+L+ S T SGKTL LA I KA G+
Sbjct: 26 LSKYSEFTPPQKYAIVEAF-KGRNVLITSPTGSGKTLAAFLAAISMLVEKAEKGELEDRV 84
Query: 263 -MLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDAD----- 316
++++ PL AL N D R+ + ++ IK ++ V TG D D
Sbjct: 85 YVVYVSPLKALNN----DIRKNLEEPLEEIYALAEKKGIKLQKIRAAVRTG-DTDAAEKQ 139
Query: 317 --------IIVGTYEGIDYLL---RAGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARL 365
I++ T E + +L + K + NV +++DEIH + + +RG L + RL
Sbjct: 140 KQARKPPHILITTPETLAIVLCSPKFSKSLTNVRFLIVDEIHAIAENKRGVHLTLSMERL 199
Query: 366 RKLYPGAQF-IGLSATIGNPEELAKAL-------GMKLVLYD---ERPVDLE-----RHL 409
+++ G IGLSATI EE+A+ L V+ D E+P+D++
Sbjct: 200 QRIQEGEMVRIGLSATISPLEEIARFLVGYNYGEERDCVIADVTFEKPMDIKVVSPINDF 259
Query: 410 VIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTG--KGLKAK 467
A E RL L + +SSK T++FT +R + L K K
Sbjct: 260 FSASAEEISDRLYDLLAEYV---KSSK----TTLIFTNTRSATERVVYHLKKRLKDFPIK 312
Query: 468 PYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREF 527
+HS L + R E E + + VV++ +L G+D ++ + +G+ S+
Sbjct: 313 AHHSSLSKEVRLEVENELKNGELRCVVSSTSLELGIDIGYIDLV---ILLGSP-KSINRA 368
Query: 528 HQMLGRAGRPLY 539
Q +GR+G L+
Sbjct: 369 LQRIGRSGHRLH 380
>sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGENIC REGION
>gi|7446091|pir||B69941 ATP-dependent RNA helicase
homolog yprA - Bacillus subtilis
>gi|1146178|gb|AAB38468.1| (L47838) helicase [Bacillus
subtilis] >gi|2634641|emb|CAB14139.1| (Z99115) similar
to ATP-dependent helicase [Bacillus subtilis]
Length = 749
Score = 74.9 bits (181), Expect = 3e-12
Identities = 108/382 (28%), Positives = 161/382 (41%), Gaps = 36/382 (9%)
Query: 178 ITKWDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLV 237
+ W E++ + K M I E+ K L GI EL Q A + + +GE+++
Sbjct: 19 VVNWHEIEPREAKTRPMPES---IDERIKAALSKRGIDELYTHQYSAFQY-VQKGESIVT 74
Query: 238 VSATASGKTLIGELAGIPKALNGK--KMLFLVPLVALANQKYEDFRRRYSKLGLKV---- 291
V+ TASGKTL L + + + L+L P ALA + + ++G+ +
Sbjct: 75 VTPTASGKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSELNEIIDEMGIDIKSFT 134
Query: 292 --AIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVIDEIHML 349
R K R+ +V T + D++ + + + N+ IVIDE+H
Sbjct: 135 YDGDTSPAIRQKVRKAGHIVIT--NPDMLHSAI--LPHHTKWVSLFENLKYIVIDELHTY 190
Query: 350 DDEERGPRLDGLIARLRKL--YPGAQ--FIGLSATIGNPEELAKAL-GMKLVLYDERPVD 404
G + +I RL+++ + G+ FI SATI NP+EL + L G + L D+
Sbjct: 191 RG-VFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPMRLVDDNGAP 249
Query: 405 LER-HLVIARNESEKWRLIAKLCKVEAMRRSSKGF---KGQTIVFTYSRRRCHELASF-- 458
R H V L + + +K F K QTIVF SR R + S
Sbjct: 250 SGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVEIILSHIQ 309
Query: 459 -LTGKGLKAKP---YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFES 514
L K + K Y G K+R+ E + I VV+T AL GVD QV +
Sbjct: 310 ELVKKEIGTKSIRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDIGQLQVCVMT 369
Query: 515 LAMGNKWLSVREFHQMLGRAGR 536
G SV Q GRAGR
Sbjct: 370 GYPG----SVASAWQQAGRAGR 387
>pir||BVECRQ DNA helicase recQ - Escherichia coli (strain K-12)
>gi|2367301|gb|AAC76825.1| (AE000458) ATP-dependent DNA
helicase [Escherichia coli K12]
Length = 610
Score = 74.9 bits (181), Expect = 3e-12
Identities = 81/333 (24%), Positives = 150/333 (44%), Gaps = 34/333 (10%)
Query: 213 GIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVAL 272
G ++ P Q I + +L G + LVV T GK+L ++ + LNG ++ + PL++L
Sbjct: 24 GYQQFRPGQEEIIDT-VLSGRDCLVVMPTGGGKSLCYQIPAL--LLNGLTVV-VSPLISL 79
Query: 273 ANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAG 332
+ + + G+ A ++ +TRE+ + V TG I Y + L+
Sbjct: 80 MKDQVDQLQAN----GVAAAC---LNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDN 132
Query: 333 ----KKIGNVGTIVIDEIHMLDDEERGPRLD-GLIARLRKLYPGAQFIGLSATIGNP--E 385
N + +DE H + R + + +LR+ +P F+ L+AT + +
Sbjct: 133 FLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDTTRQ 192
Query: 386 ELAKALGMKLVLYDERPVDLE--RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTI 443
++ + LG+ L D R++++ EK++ + +L + +R G I
Sbjct: 193 DIVRLLGLNDPLIQISSFDRPNIRYMLM-----EKFKPLDQLMRYVQEQRGKSG-----I 242
Query: 444 VFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGV 503
++ SR + + A+ L KG+ A YH+GL R + +FQ + +VV T A G G+
Sbjct: 243 IYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGI 302
Query: 504 DFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
+ P + + N + ++Q GRAGR
Sbjct: 303 NKPNVRFVVHFDIPRN----IESYYQETGRAGR 331
>sp|P15043|RECQ_ECOLI ATP-DEPENDENT DNA HELICASE RECQ
Length = 608
Score = 74.9 bits (181), Expect = 3e-12
Identities = 81/333 (24%), Positives = 150/333 (44%), Gaps = 34/333 (10%)
Query: 213 GIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVAL 272
G ++ P Q I + +L G + LVV T GK+L ++ + LNG ++ + PL++L
Sbjct: 22 GYQQFRPGQEEIIDT-VLSGRDCLVVMPTGGGKSLCYQIPAL--LLNGLTVV-VSPLISL 77
Query: 273 ANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAG 332
+ + + G+ A ++ +TRE+ + V TG I Y + L+
Sbjct: 78 MKDQVDQLQAN----GVAAAC---LNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDN 130
Query: 333 ----KKIGNVGTIVIDEIHMLDDEERGPRLD-GLIARLRKLYPGAQFIGLSATIGNP--E 385
N + +DE H + R + + +LR+ +P F+ L+AT + +
Sbjct: 131 FLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDTTRQ 190
Query: 386 ELAKALGMKLVLYDERPVDLE--RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTI 443
++ + LG+ L D R++++ EK++ + +L + +R G I
Sbjct: 191 DIVRLLGLNDPLIQISSFDRPNIRYMLM-----EKFKPLDQLMRYVQEQRGKSG-----I 240
Query: 444 VFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGV 503
++ SR + + A+ L KG+ A YH+GL R + +FQ + +VV T A G G+
Sbjct: 241 IYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGI 300
Query: 504 DFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
+ P + + N + ++Q GRAGR
Sbjct: 301 NKPNVRFVVHFDIPRN----IESYYQETGRAGR 329
>gi|6323844 has DNA helicase signature motifs; Sgs1p [Saccharomyces cerevisiae]
>gi|464912|sp|P35187|SGS1_YEAST HELICASE SGS1 (HELICASE
TPS1) >gi|1077094|pir||S50918 DNA helicase TPS1 - yeast
(Saccharomyces cerevisiae) >gi|349194|gb|AAA35167.1|
(L07870) bps. 390..881 = homology to E.coli recQ; bps.
414..430 = ATP binding site [Saccharomyces cerevisiae]
>gi|642282|emb|CAA87811.1| (Z47815) Tps1p [Saccharomyces
cerevisiae] >gi|726279|gb|AAB60289.1| (U22341) Sgs1p
[Saccharomyces cerevisiae]
Length = 1447
Score = 73.7 bits (178), Expect = 8e-12
Identities = 79/345 (22%), Positives = 153/345 (43%), Gaps = 32/345 (9%)
Query: 204 KFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKK- 262
+ ++ KL G + P Q+ A+ + L+G+++ V+ T GK+L +L + K+ GK
Sbjct: 669 RLHEVFKLPGFR---PNQLEAVNA-TLQGKDVFVLMPTGGGKSLCYQLPAVVKS--GKTH 722
Query: 263 --MLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPV--VVDTGIDADII 318
+ + PL++L + E + K + + R +T + ++D + +
Sbjct: 723 GTTIVISPLISLMQDQVEHLLNKNIKASMFSSRGTAEQRRQTFNLFINGLLDLVYISPEM 782
Query: 319 VGTYEGIDYLLRAGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARL-RKLYPGAQFIGL 377
+ E + G + IV+DE H + + R D + ++ YP I L
Sbjct: 783 ISASEQCKRAISRLYADGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIAL 842
Query: 378 SATIGNPEELAKALGMKLVLYDERPVDLER-----HLVIARNESEKWRLIAKLCKVEAMR 432
+AT + ++L + PV L++ +L N+ K I ++C R
Sbjct: 843 TATASEQVRMDIIHNLEL----KEPVFLKQSFNRTNLYYEVNKKTK-NTIFEICDAVKSR 897
Query: 433 RSSKGFKGQT-IVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMID 491
FK QT I++ +S++ C + ++ + G+K YH+G+ +R + +QA I
Sbjct: 898 -----FKNQTGIIYCHSKKSCEQTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQADEIQ 952
Query: 492 VVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
V+ T A G G+D P + ++ ++ ++Q GRAGR
Sbjct: 953 VICATVAFGMGIDKPDVRFVYHFTVP----RTLEGYYQETGRAGR 993
>emb|CAA68194.1| (X99938) RNA helicase [Arabidopsis thaliana]
Length = 671
Score = 73.4 bits (177), Expect = 1e-11
Identities = 125/525 (23%), Positives = 206/525 (38%), Gaps = 66/525 (12%)
Query: 133 KRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITKWDELKAKRIKVE 192
K+E + + + E K+ K + DK A + + K K ++ VE
Sbjct: 32 KKEQKLKLSDSDEEESEKK---KSKKKDKKRKASEEEDEVKSDSSSEKKKSSKKVKLGVE 88
Query: 193 RMTIDELDIPEKFK------DILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKT 246
+ +D + KF+ + LK GI+ L P+Q +L+G +L+ + T GKT
Sbjct: 89 DVEVDNPNAVSKFRISAPLREKLKANGIEALFPIQASTFDM-VLDGADLVGRARTGQGKT 147
Query: 247 LIGELAGIPKALNG-----KKM--------LFLVPLVALANQKYEDFRRRYSKLGLKVAI 293
L L + +NG +KM L L+P LA Q DF LGL
Sbjct: 148 LAFVLPILESLVNGPAKSKRKMGYGRSPSVLVLLPTRELAKQVAADFDAYGGSLGLSSCC 207
Query: 294 RVGMSRIKTREEPVVVDTGIDADIIVGTYEGI-DYLLRAGKKIGNVGTIVIDEIHMLDDE 352
G I +E + G+D I+VGT I D++ R V+DE D+
Sbjct: 208 LYGGDSIPVQEGKL--KRGVD--IVVGTPGRIKDHIERQNLDFSYFKFRVLDEA---DEM 260
Query: 353 ERGPRLDGLIARLRKLYPGA--QFIGLSATIGNPEELAKALGMKLVLYDERPVDLE---- 406
R ++ + L K+ Q + SAT+ + K + + + D++ +DL
Sbjct: 261 LRMGFVEDVELILGKVEDSTKVQTLLFSATLPS---WVKNISNRFLKRDQKTIDLVGNDK 317
Query: 407 -------RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFL 459
RH+ I N++ RLI + S GQTI+F ++ + EL+ L
Sbjct: 318 MKASNSVRHIAIPCNKAAMARLIPDII-------SCYSSGGQTIIFAETKVQVSELSGLL 370
Query: 460 TGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGN 519
G ++ H +P QR++T F+ +V T G+D Q+I +
Sbjct: 371 DG----SRALHGEIPQSQREVTLAGFRNGKFATLVATNVAARGLDINDVQLIIQC----- 421
Query: 520 KWLSVREFHQMLGRAGRPLYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVI 579
RE + R+GR V + + RK S E + + L +P +P
Sbjct: 422 --EPPREVEAYIHRSGRTGRAGNTGVPVTLYDSRKSSVSRIEKEAGIKFEHLAAP-QPDE 478
Query: 580 VEWSDEIEEDNVLAHACVFNRLSVIEEVNSLTLGANRSAEKVLEK 624
+ S +E + C + +E L + SAE +L K
Sbjct: 479 IARSGGMEAAEKVKQVCDSVVPAFLEAAKELLETSGLSAEVLLAK 523
>dbj|BAA97183.1| (AB019235) RNA helicase [Arabidopsis thaliana]
Length = 671
Score = 72.6 bits (175), Expect = 2e-11
Identities = 124/525 (23%), Positives = 206/525 (38%), Gaps = 66/525 (12%)
Query: 133 KRELRARFNSIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQHPEITKWDELKAKRIKVE 192
K+E + + + E K+ K + DK A + + K K ++ VE
Sbjct: 32 KKEQKLKLSDSDEEESEKK---KSKKKDKKRKASEEEDEVKSDSSSEKKKSSKKVKLGVE 88
Query: 193 RMTIDELDIPEKFK------DILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKT 246
+ +D + KF+ + LK GI+ L P+Q +L+G +L+ + T GKT
Sbjct: 89 DVEVDNPNAVSKFRISAPLREKLKANGIEALFPIQASTFDM-VLDGADLVGRARTGQGKT 147
Query: 247 LIGELAGIPKALNG-----KKM--------LFLVPLVALANQKYEDFRRRYSKLGLKVAI 293
L L + +NG +KM L L+P LA Q DF LGL
Sbjct: 148 LAFVLPILESLVNGPAKSKRKMGYGRSPSVLVLLPTRELAKQVAADFDAYGGSLGLSSCC 207
Query: 294 RVGMSRIKTREEPVVVDTGIDADIIVGTYEGI-DYLLRAGKKIGNVGTIVIDEIHMLDDE 352
G +E + G+D I+VGT I D++ R + V+DE D+
Sbjct: 208 LYGGDSYPVQEGKL--KRGVD--IVVGTPGRIKDHIERQNLDFSYLQFRVLDEA---DEM 260
Query: 353 ERGPRLDGLIARLRKLYPGA--QFIGLSATIGNPEELAKALGMKLVLYDERPVDLE---- 406
R ++ + L K+ Q + SAT+ + K + + + D++ +DL
Sbjct: 261 LRMGFVEDVELILGKVEDSTKVQTLLFSATLPS---WVKNISNRFLKRDQKTIDLVGNDK 317
Query: 407 -------RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFL 459
RH+ I N++ RLI + S GQTI+F ++ + EL+ L
Sbjct: 318 MKASNSVRHIAIPCNKAAMARLIPDII-------SCYSSGGQTIIFAETKVQVSELSGLL 370
Query: 460 TGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGN 519
G ++ H +P QR++T F+ +V T G+D Q+I +
Sbjct: 371 DG----SRALHGEIPQSQREVTLAGFRNGKFATLVATNVAARGLDINDVQLIIQC----- 421
Query: 520 KWLSVREFHQMLGRAGRPLYHEKGKVYLMVEPGRKYSAQMEGTEDEVALKLLTSPIEPVI 579
RE + R+GR V + + RK S E + + L +P +P
Sbjct: 422 --EPPREVEAYIHRSGRTGRAGNTGVAVTLYDSRKSSVSRIEKEAGIKFEHLAAP-QPDE 478
Query: 580 VEWSDEIEEDNVLAHACVFNRLSVIEEVNSLTLGANRSAEKVLEK 624
+ S +E + C + +E L + SAE +L K
Sbjct: 479 IARSGGMEAAEKVKQVCDSVVPAFLEAAKELLETSGLSAEVLLAK 523
>pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949397|gb|AAG06660.1|AE004749_9 (AE004749) probable
ATP-dependent DNA helicase [Pseudomonas aeruginosa]
Length = 1448
Score = 72.6 bits (175), Expect = 2e-11
Identities = 98/361 (27%), Positives = 163/361 (45%), Gaps = 59/361 (16%)
Query: 219 PVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKAL-----------NGKKMLFLV 267
P QV A + + EG + LV + T SGKTL LA I + + +++++
Sbjct: 38 PAQVEAWPA-IREGLSTLVAAPTGSGKTLTAFLAAIDALVVEGLAAGGELADATQVVYVS 96
Query: 268 PLVALAN-------QKYEDFRRRYSKLGLK-VAIRVGMSRIKTREEPVVVDTGI---DAD 316
PL AL+N Q R ++LGL V IR S ++T + P V +
Sbjct: 97 PLKALSNDIRINLEQPLAGIREELARLGLPDVDIR---SAVRTGDTPQVERGAMRKRPPH 153
Query: 317 IIVGTYEGIDYLL--RAGKK-IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQ 373
I+V T E + LL +G++ + V ++++DEIH L +RG L + RL+ L P
Sbjct: 154 ILVTTPESLYILLGSESGRQMLAGVRSVIVDEIHALAGSKRGSHLALSLERLQALCPRPL 213
Query: 374 F-IGLSATIGNPEELAKAL----------GMKLV-LYDERPVDLERHL----VIARNESE 417
IGLSAT E++A+ L ++V + RP DL + + A ++
Sbjct: 214 LRIGLSATQKPIEKVARFLVGASGNPRDPACRIVDVGYTRPRDLGIEVPPVALEAVMSND 273
Query: 418 KWRLI-AKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGK--GLKAKPYHSGLP 474
W L+ +L + R+ T+VF +RR + FL + + +H L
Sbjct: 274 TWELVYDRLAHLAGEHRT-------TLVFVNTRRMAERVTRFLAERLGSRQVAAHHGSLA 326
Query: 475 YKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRA 534
+ R E +A + V+V TA+L G+D +++ + + S+ F Q +GR+
Sbjct: 327 KELRLDAEQRLKAGQLKVLVATASLELGIDIGDVELVCQL----SSPRSIAAFLQRVGRS 382
Query: 535 G 535
G
Sbjct: 383 G 383
>gb|AAF59592.1| (AC024820) contains similarity to TR:O18475 [Caenorhabditis
elegans]
Length = 563
Score = 72.2 bits (174), Expect = 2e-11
Identities = 58/190 (30%), Positives = 97/190 (50%), Gaps = 12/190 (6%)
Query: 229 LLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLV-PLVALANQKYEDFRRRYSKL 287
LL+GEN ++ T +GKTLI E+ + +A+ K+ LV P VA+ +K
Sbjct: 213 LLDGENCILSLPTGAGKTLIAEVLMLREAIVRKRNAILVLPYVAIVQEKISALAPFEDAF 272
Query: 288 GLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRA---GKKIGNVGTIVID 344
G+ + + K R P+ + + V T E + L+ + ++ VG +V+D
Sbjct: 273 GINIE---EYASNKGRFPPIKRRKRVS--VYVATIEKANMLINSLITQGQLDRVGMVVVD 327
Query: 345 EIHMLDDEERGPRLDGLIARLRKLYPG-AQFIGLSATIGNPEELAKALGMKLVLYDERPV 403
E+HM+ D RG L+ L+A+ LY G Q +G+SAT+ N ++L AL + + RPV
Sbjct: 328 ELHMIGDGGRGAILEQLLAKF--LYKGTGQIVGMSATLPNIDDLKFALRAFVYSTNFRPV 385
Query: 404 DLERHLVIAR 413
+L + I +
Sbjct: 386 ELTEFVKIGQ 395
>sp|P46064|YMR1_CAEEL PUTATIVE ATP-DEPENDENT DNA HELICASE K02F3.1 IN CHROMOSOME III
>gi|7505165|pir||T16536 hypothetical protein K02F3.1 -
Caenorhabditis elegans
Length = 886
Score = 71.8 bits (173), Expect = 3e-11
Identities = 102/457 (22%), Positives = 190/457 (41%), Gaps = 54/457 (11%)
Query: 123 ICERCA----EEELKRELRARFN---SIGMFEQAKRLLEKFRDLDKVLYAFDPRFDPTQH 175
+ ERC EE+ ++ RF+ ++ +L + DLD + D + +
Sbjct: 373 LAERCGVGYENEEIIHQICDRFSLHPNLMSDVLLSKLSTELADLDGEIGQIDQQISQLRR 432
Query: 176 PEITKWDELKAKRIKVERMTIDELDI-------------PEKFKDILKLEGIKELLPVQV 222
+ + +A K+E T ++ D+ E K + + +++ P+Q
Sbjct: 433 KKSELTQKRQAIERKIELKTNEDSDVVTDRWDRDGFPWSDEATKILKEQFHLEKFRPLQR 492
Query: 223 LAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRR 282
AI + ++ E+ +V+ +T GK+L +L P L L + PL++L + R
Sbjct: 493 AAINA-VMSKEDAVVILSTGGGKSLCYQL---PALLANGLALVVSPLISLVEDQILQLR- 547
Query: 283 RYSKLGL-KVAIRVGMSRIKT-REEPVVVDTGIDADIIVGTYEGIDYLLRAGKK------ 334
LG+ ++ S+ + R E + + ++ T E + + K
Sbjct: 548 ---SLGIDSSSLNANTSKEEAKRVEDAITNKDSKFRLLYVTPEKLAKSKKMMNKLEKSLS 604
Query: 335 IGNVGTIVIDEIHMLDDEERGPRLD-GLIARLRKLYPGAQFIGLSATIGNP--EELAKAL 391
+G + I IDE+H R D + L++ + G +GL+AT + +++ L
Sbjct: 605 VGFLKLIAIDEVHCCSQWGHDFRTDYSFLNVLKRQFKGVPILGLTATATSNVLDDVKDML 664
Query: 392 GMKLVLYDERPVDLE--RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQT-IVFTYS 448
G++ L + ++ V+ + SE C E + + F GQT I++ S
Sbjct: 665 GIQAALTFRAGFNRSNLKYKVVQKPGSEDE------CTEEIAKTIKRDFAGQTGIIYCLS 718
Query: 449 RRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPAS 508
R C ++A L G+KAK YH+ + R + + I V+V T A G G+D P
Sbjct: 719 RNDCEKVAKALKSHGIKAKHYHAYMEPVDRSGAHQGWISGKIQVIVATVAFGMGIDKPNV 778
Query: 509 Q-VIFESLAMGNKWLSVREFHQMLGRAGRPLYHEKGK 544
+ VI SL S+ ++Q R + +K K
Sbjct: 779 RFVIHHSLPK-----SIENYYQASARILLRMTKQKNK 810
>gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobacterium sp. NRC-1]
Length = 946
Score = 71.4 bits (172), Expect = 4e-11
Identities = 86/330 (26%), Positives = 140/330 (42%), Gaps = 36/330 (10%)
Query: 229 LLEGENLLVVSATASGKTLIGELAGIP--KAL-------NGKKMLFLVPLVALANQKYED 279
L +G N LVV+ T +GKT E A +P AL +G L++ PL AL E
Sbjct: 42 LADGRNGLVVAPTGTGKT---ETAMLPVFDALVSDGGPPDGFGALYVTPLRALNRDMRER 98
Query: 280 FRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKK---IG 336
LGL+V +R G + R + D++V T E + +L +
Sbjct: 99 LDWWGETLGLEVDVRHGDTTDYQRRQQATDPP----DVLVTTPETLQAMLTGSTLRDGLA 154
Query: 337 NVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKAL----G 392
+V +V+DE+H L +RG +L + RL ++ Q IGLSAT+G+P E+ L G
Sbjct: 155 DVEHVVVDEVHELAGAKRGAQLAIGLERLVEVAGRVQRIGLSATVGDPHEIGAFLTGGRG 214
Query: 393 MKLVLYD-ERPVDLERHLVIARNESEKWRLIAKLCKVEAMRRSSKGFK------GQTIVF 445
+++ D V E + E RL ++L AM + + ++F
Sbjct: 215 CEIIEVDVTSNVSFEVREPAVTDADE--RLASELLTTPAMASHVRAIREIVDRHDSVLIF 272
Query: 446 TYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDF 505
+R+ L S +H L R E F++ +D ++ T+++ G+D
Sbjct: 273 VNTRQTAEALGSRFKELDANIGVHHGSLSKDARIDVEDRFKSGDLDGLLCTSSMELGIDV 332
Query: 506 PASQVIFESLAMGNKWLSVREFHQMLGRAG 535
+ + N V+ Q +GRAG
Sbjct: 333 GG----IDHVVQYNSPREVKRLLQRVGRAG 358
>gb|AAD18127.1| (U89166) ECORLD_ORF3; putative DNA enzyme; similar to H. influenzae
DNA-dependent ATPase/DNA helicase encoded by GenBank
Accession Number U32756 [Eikenella corrodens]
Length = 439
Score = 70.6 bits (170), Expect = 7e-11
Identities = 81/321 (25%), Positives = 133/321 (41%), Gaps = 32/321 (9%)
Query: 225 IKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRRY 284
I + L EG+NLLV+ T GK+L + IP + + + PL+AL + + +
Sbjct: 26 IVNALAEGQNLLVLMPTGGGKSLCYQ---IPALMRRGLAVVVSPLIALMDDQVAALQAA- 81
Query: 285 SKLGLKVA-IRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLLRAGKKIGNVGTIVI 343
G+ A + G+S + ++ ++ G + V + + I
Sbjct: 82 ---GVAAASVHSGISSSQVQQIADTIEAGYLKLLYVSPERLVSERFLRFLDHTEISLFAI 138
Query: 344 DEIHMLD----DEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLYD 399
DE H + D R GL+A YP I L+AT +KL
Sbjct: 139 DEAHCVSQWGHDFRPEYRQLGLLA---DRYPSIPRIALTATADAETRADIKHYLKLENAA 195
Query: 400 ERPVDLER----HLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRCHEL 455
E +R + +I +N +K L + + G G IV+ SR++ +
Sbjct: 196 EYIASFDRPNIYYQIIEKNNGKKQLL-------DFLHSRPHGESG--IVYCLSRKKVEDT 246
Query: 456 ASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFESL 515
A+FL G +A PYH+GL +R + F + ++V T A G G+D P + +
Sbjct: 247 AAFLNEHGYRALPYHAGLTMTERNENQHRFTREEGLIIVATVAFGMGIDKPDVRFV---- 302
Query: 516 AMGNKWLSVREFHQMLGRAGR 536
A + S+ F+Q GRAGR
Sbjct: 303 AHLDMPQSIEHFYQESGRAGR 323
>pir||F72253 hypothetical protein TM1450 - Thermotoga maritima (strain MSB8)
>gi|4982014|gb|AAD36518.1|AE001796_10 (AE001796)
transcription-repair coupling factor, putative
[Thermotoga maritima]
Length = 893
Score = 70.2 bits (169), Expect = 9e-11
Identities = 128/515 (24%), Positives = 203/515 (38%), Gaps = 70/515 (13%)
Query: 61 EIEKLLRQSRIVLVNADEWEDYFKRRLMN---KNVEKASLCRLCLLEGR-------ITVL 110
E K ++ R +L + + D+F R++ KNVEK S +E + + +
Sbjct: 193 EYRKFRKEMRDLL--KERYNDFFDERVVEVILKNVEKGSAPLSTRVEKKESLPILDVDEI 250
Query: 111 TEGNRIKYRGEYICERCAEEELKRELRARFNSIGMFEQAKRLLEKFRDLDKV-LYAFDPR 169
EG + +R I LK L R +E A L +D+V Y DP
Sbjct: 251 EEGGLVVHREHGIAIFEGIVRLKGVLGERDYLKLKYEDAI-LYVPIEKIDRVHKYIGDPS 309
Query: 170 FDPTQHPEITKWDE-LKAKRIKVERMTIDELDIPEKFKDI--LKLEGIKEL--------- 217
KW + LK R +E+ + +++ K ++ L L G EL
Sbjct: 310 QVKLDRMNRGKWKQTLKKVREDIEKKIKELVELYMKRQEAQGLSLPGDPELEEKFAESFP 369
Query: 218 ---LPVQVLAIKSGL--LEGE---NLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPL 269
P Q +I+ L L E + L+ GKT + A +GK++ LVP
Sbjct: 370 YIETPDQQQSIEEVLSDLASEKPMDRLLCGDAGVGKTEVALRAAFRAVASGKQVAVLVPT 429
Query: 270 VALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDYLL 329
LA Q YE+F+ R G+KV + + ++E + + DII+GT+ LL
Sbjct: 430 TVLARQHYENFKERMEPFGVKVELLDSSRTAREKKEIIEKLKKGEIDIIIGTHS----LL 485
Query: 330 RAGKKIGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAK 389
+ ++G ++IDE E++ R +KL + LSAT P L
Sbjct: 486 NERIEFSDLGLVIIDEEQKFGVEQK--------ERFKKLRLSVNVLTLSAT-PIPRTLHM 536
Query: 390 AL-GMK--LVLYDERPVDLERHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFT 446
AL GMK V+ P ++ +A + L K +R ++G GQ I
Sbjct: 537 ALSGMKDFSVINSPPPGRKPVYVYVAEYSDD-------LVKGAVIREINRG--GQVI--- 584
Query: 447 YSRRRCHELASFLTG-----KGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGA 501
Y R EL L+ H + K + EF IDV++ T +
Sbjct: 585 YVHNRVEELPEVFEKLKRMFPELEIAVAHGKMSRKTMERIVHEFYRGNIDVLLCTTIIEN 644
Query: 502 GVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536
GVD P + + A + + + +Q+ GR GR
Sbjct: 645 GVDIPNANTLIVDDA---QRYGLSQLYQLRGRVGR 676
>gb|AAF40306.1|AF156667_1 (AF156667) RNA helicase [Vigna radiata]
Length = 713
Score = 70.2 bits (169), Expect = 9e-11
Identities = 125/557 (22%), Positives = 226/557 (40%), Gaps = 85/557 (15%)
Query: 174 QHPEITKWDELKAKRIKVERMTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGE 233
+ P + + +E + K K + + +L I E + LK +GI+ L P+Q + +L+G
Sbjct: 111 EQPLVMEAEEKEEK--KEDPNAVSKLRISEPLRLKLKEKGIESLFPIQAMTFDL-VLDGS 167
Query: 234 NLLVVSATASGKTLIGELAGIPKALNGK-------------KMLFLVPLVALANQKYEDF 280
+L+ + T GKTL L + +NG +L L+P LA + + DF
Sbjct: 168 DLVGRARTGQGKTLAFVLPILESLINGPTKSSRKTGYGRTPSVLVLLPTRELACRVHADF 227
Query: 281 RRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGI-DYLLRAGKKIGNVG 339
+GL G + T+E + + G+D I++GT + D++ R + +
Sbjct: 228 EVYGGAMGLSSCCLYGGAPYNTQE--IKLRRGVD--IVIGTPGRVKDHIERGNIDLSQLK 283
Query: 340 TIVIDE------IHMLDDEERGPRLDGLIARLRKLYPGAQFIGLSATIGNPEELAKALGM 393
V+DE + ++D E + G + + K+ Q + SAT+ + K +
Sbjct: 284 FRVLDEADEMLRMGFVEDVEL---ILGKVENVNKV----QTLLFSATL---PDWVKHIAA 333
Query: 394 KLVLYDERPVDLE-----------RHLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQT 442
+ + D++ DL RH+V+ + + +LI + +R S G G+T
Sbjct: 334 QFLKPDKKTADLVGNTKMKASTNVRHIVLPCSAPARSQLIPDI-----IRCYSSG--GRT 386
Query: 443 IVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAG 502
I+FT ++ +LA L G A+ H + QR++T F++ +V T G
Sbjct: 387 IIFTETKESASQLAGLLPG----ARALHGDIQQAQREVTLFGFRSGKFMTLVATNVAARG 442
Query: 503 VDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYHEKGKVYLMVEPGRKYSAQMEGT 562
+D Q+I + V + GR GR G + +P R +++E
Sbjct: 443 LDINDVQLIIQC----EFPREVESYIHRSGRTGRA--GNTGVAGTLYDPKRSNISKIE-R 495
Query: 563 EDEVALKLLTSPIEPVIVEWSDEIEEDNVLAHACVFNRLSVIEEVNSLTLGANRSAEKVL 622
E V + +++P + +A A +I +V+ + A + + L
Sbjct: 496 ESGVKFEHISAP-------------RPDDIAKAVGGEAAEMITQVSDSVIPAFKETAEEL 542
Query: 623 EKLEELGMVKLHG-GIVRVTPYGRATSMSFLLPREAEFIRENLDNMNPLDIAIMLSPFEN 681
K L +V+L + + Y S L E ++ L+ P I F
Sbjct: 543 LKSSGLTVVELLAKALAKAVGYTEIKQRSLLTSME-NYVTLLLEIGKP----IFTPSFAY 597
Query: 682 AYLPGFLQREIESAVRG 698
L FL E AV+G
Sbjct: 598 GILRRFLPEEKVEAVKG 614
>pir||H81794 ATP-dependent DNA helicase (EC 3.6.1.-) NMA2213 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380832|emb|CAB85424.1| (AL162758) ATP-dependent DNA
helicase [Neisseria meningitidis Z2491]
Length = 766
Score = 70.2 bits (169), Expect = 9e-11
Identities = 88/324 (27%), Positives = 140/324 (43%), Gaps = 36/324 (11%)
Query: 224 AIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGKKMLFLVPLVALANQKYEDFRRR 283
+I + L G +L+V+ T GK+L + IP + + + PL+AL N + +
Sbjct: 25 SIVNALAGGRSLMVLMPTGGGKSLCYQ---IPALMREGVAVVVSPLIALMNDQVANLH-- 79
Query: 284 YSKLGLKVA-IRVGMSRIKTREEPVVVDTGIDADIIVGTYEGI-DYLLRAGKKIGNVGTI 341
G++ A + G S + RE + G + V + D LR + V
Sbjct: 80 --VAGIEAAAVNSGTSADEAREIADKLAQGRLKLLYVAPERLVTDRFLRFLDQ-QTVSLF 136
Query: 342 VIDEIHMLDDEERGPRLD-GLIARLRKLYPGAQFIGLSATIGNPEELAKALGMKLVLY-D 399
IDE H + R + + L + YP I L+AT + A +K L+ D
Sbjct: 137 AIDEAHCVSQWGHDFRPEYQQLGMLAERYPNVPRIALTATA----DAATRADIKHYLHLD 192
Query: 400 ERPVDLER-------HLVIARNESEKWRLIAKLCKVEAMRRSSKGFKGQTIVFTYSRRRC 452
+ P + + VI +N +K L + +R+ G G IV+ SR++
Sbjct: 193 DAPEFVSSFDRPNIYYQVIEKNNGKKQLL-------DFIRKEMTGQSG--IVYCLSRKKV 243
Query: 453 HELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIF 512
++A FL GL A PYH+GL R+ + F + +VV T A G G+D P + +
Sbjct: 244 EDVAQFLRENGLNAIPYHAGLSMDVREENQRRFTHEDNIIVVATVAFGMGIDKPDVRFV- 302
Query: 513 ESLAMGNKWLSVREFHQMLGRAGR 536
A + SV F+Q GRAGR
Sbjct: 303 ---AHLDMPQSVEHFYQESGRAGR 323
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.140 0.396
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 306202883
Number of Sequences: 2977
Number of extensions: 12986680
Number of successful extensions: 35625
Number of sequences better than 1.0e-10: 70
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 35355
Number of HSP's gapped (non-prelim): 143
length of query: 855
length of database: 189,106,746
effective HSP length: 59
effective length of query: 796
effective length of database: 153,796,013
effective search space: 122421626348
effective search space used: 122421626348
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 169 (70.2 bits)