BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2320 (cobS) DE:cobalamin (5'-phosphate) synthase (cobS-1)
(232 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75189 cobalamin (5'-phosphate) synthase (cobs-1) PAB2320 -... 458 e-128
dbj|BAA11941.1| (D83525) cobalamin (5'-phosphate) synthase [Pyro... 358 3e-98
pir||B71145 probable cobalamin synthase - Pyrococcus horikoshii ... 340 9e-93
gi|11499904 cobalamin (5'-phosphate) synthase (cobS-2) [Archaeog... 128 5e-29
gi|11497658 cobalamin (5'-phosphate) synthase (cobS-1) [Archaeog... 119 3e-26
pir||E64479 cobalamin (5'-phosphate) synthase - Methanococcus ja... 103 2e-21
emb|CAC12207.1| (AL445066) cobalamin synthase related protein [T... 98 7e-20
gb|AAK43328.1| Cobalamin synthase related protein [Sulfolobus so... 82 8e-15
sp|Q05602|COBS_SALTY COBALAMIN [5'-PHOSPHATE] SYNTHASE >gi|15443... 81 1e-14
pir||G83486 cobalamin (5'-phosphate) synthase PA1281 [imported] ... 79 4e-14
sp|P36561|COBS_ECOLI COBALAMIN [5'-PHOSPHATE] SYNTHASE >gi|74454... 78 9e-14
gb|AAA78907.1| (U33333) cobalamin synthase [Escherichia coli] 78 1e-13
pir||H75576 cobalamin synthase - Deinococcus radiodurans (strain... 72 7e-12
pir||T03519 cobalamin (5'-phosphate) synthase homolog - Rhodobac... 70 2e-11
pir||A69015 cobalamin (5'-phosphate) synthase - Methanobacterium... 69 4e-11
gb|AAA56875.1| (L25054) cobalamine (5'-phosphate) synthase; CobS... 69 5e-11
>pir||H75189 cobalamin (5'-phosphate) synthase (cobs-1) PAB2320 - Pyrococcus
abyssi (strain Orsay) >gi|5457476|emb|CAB48967.1|
(AJ248283) cobalamin (5'-phosphate) synthase (cobS-1)
[Pyrococcus abyssi]
Length = 232
Score = 458 bits (1166), Expect = e-128
Identities = 232/232 (100%), Positives = 232/232 (100%)
Query: 1 MRNILPFLTRIPVKGDFEKARNELWAFPLVSLVSSIIPIAILYLRIPLANVLALLSLYFV 60
MRNILPFLTRIPVKGDFEKARNELWAFPLVSLVSSIIPIAILYLRIPLANVLALLSLYFV
Sbjct: 1 MRNILPFLTRIPVKGDFEKARNELWAFPLVSLVSSIIPIAILYLRIPLANVLALLSLYFV 60
Query: 61 IGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPFYA 120
IGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPFYA
Sbjct: 61 IGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPFYA 120
Query: 121 IYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDPSA 180
IYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDPSA
Sbjct: 121 IYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDPSA 180
Query: 181 LFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILSFSLCFTT 232
LFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILSFSLCFTT
Sbjct: 181 LFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILSFSLCFTT 232
>dbj|BAA11941.1| (D83525) cobalamin (5'-phosphate) synthase [Pyrococcus sp.]
Length = 231
Score = 358 bits (910), Expect = 3e-98
Identities = 170/225 (75%), Positives = 206/225 (91%)
Query: 1 MRNILPFLTRIPVKGDFEKARNELWAFPLVSLVSSIIPIAILYLRIPLANVLALLSLYFV 60
MRNILPFLTRIPVKGDFEKARNELWAFPLV+LVSS +P ILYL +PL+N+LA+L+LY+
Sbjct: 1 MRNILPFLTRIPVKGDFEKARNELWAFPLVALVSSALPTLILYLGLPLSNLLAVLALYWT 60
Query: 61 IGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPFYA 120
IGLLHLDGLADWADGIM KGDRERKI+ MKD+NTGIAG+FAVV+VL LQVYSL +LPFYA
Sbjct: 61 IGLLHLDGLADWADGIMAKGDRERKIEVMKDVNTGIAGLFAVVIVLLLQVYSLQLLPFYA 120
Query: 121 IYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDPSA 180
+++AELNSK++MLL LATK+PLG+GLGAYFMEGMNGRQLA+G +LYVLL L VV+++P A
Sbjct: 121 LFLAELNSKYAMLLALATKRPLGKGLGAYFMEGMNGRQLALGTLLYVLLGLSVVLFEPRA 180
Query: 181 LFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILS 225
L G++GL+F ++IR+SL+NF G+NGDCLGA AEITRAGTLV+++
Sbjct: 181 LAGILGLLFGVHIIRISLKNFDGLNGDCLGATAEITRAGTLVVMA 225
>pir||B71145 probable cobalamin synthase - Pyrococcus horikoshii
>gi|3256764|dbj|BAA29447.1| (AP000002) 230aa long
hypothetical cobalamin synthase [Pyrococcus horikoshii]
Length = 230
Score = 340 bits (863), Expect = 9e-93
Identities = 156/225 (69%), Positives = 196/225 (86%)
Query: 1 MRNILPFLTRIPVKGDFEKARNELWAFPLVSLVSSIIPIAILYLRIPLANVLALLSLYFV 60
M+NILPFLTRIP+KGDFEKAR ELWAFPLVS+ +S +P ILYL++PLA++LALLSLYF
Sbjct: 1 MKNILPFLTRIPIKGDFEKARRELWAFPLVSVFTSPLPALILYLKVPLASILALLSLYFT 60
Query: 61 IGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPFYA 120
IGLLHLDGLADWADGIMVKGDRE+KIKAMKD+N G+AG+FAVV VL LQ+YSL ++PFYA
Sbjct: 61 IGLLHLDGLADWADGIMVKGDREKKIKAMKDINVGVAGIFAVVTVLMLQIYSLQLVPFYA 120
Query: 121 IYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDPSA 180
I++AELNSKF+MLL +ATKKPLG+GLGAYFME ++ QL G ++Y+LLY+PV+I +P
Sbjct: 121 IFLAELNSKFAMLLAMATKKPLGKGLGAYFMEALDRNQLLYGTLIYLLLYIPVIIAEPRN 180
Query: 181 LFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILS 225
L +GL Y +++SL+NFGG+NGDC+GA+AEITR GTLV+++
Sbjct: 181 LVSFLGLFIGLYAVKISLDNFGGLNGDCIGAVAEITRVGTLVVIT 225
>gi|11499904 cobalamin (5'-phosphate) synthase (cobS-2) [Archaeoglobus fulgidus]
>gi|7430169|pir||C69540 cobalamin (5'-phosphate)
synthase (cobS-2) homolog - Archaeoglobus fulgidus
>gi|2648196|gb|AAB88933.1| (AE000944) cobalamin
(5'-phosphate) synthase (cobS-2) [Archaeoglobus
fulgidus]
Length = 231
Score = 128 bits (319), Expect = 5e-29
Identities = 86/232 (37%), Positives = 139/232 (59%), Gaps = 13/232 (5%)
Query: 1 MRNILPFLTRIPVKGDFEKARNELWAFPLVSLVSSIIPIAILYLRIPL-ANVLALLSLYF 59
+R+ + FLT +P+ GD E+ R LW FP +++ ++I ++R + LAL+
Sbjct: 5 IRSAISFLTTLPLGGDVEELRKNLWLFPYAAILIALIVSVPHFIRNFVDIRFLALVLYLG 64
Query: 60 VIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYS-LSMLPF 118
G+ H+DGLAD+ D + +R+R+ A+KDLNTG GV AVVVV FL +Y+ L F
Sbjct: 65 AEGINHVDGLADFGDALFAPKNRKRE--AIKDLNTGAGGV-AVVVVYFLLLYTLLYRSDF 121
Query: 119 YAIYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDP 178
+ I ++++ +K+SMLL + +P G+G+YFME ++ + + IG V VLL V I
Sbjct: 122 WEIALSQVLAKYSMLLLMLLSRPSWDGMGSYFMEKISSKDVFIGAVPVVLLCYKVGIESL 181
Query: 179 SAL---FGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILSFS 227
+AL F V+ L+ A+ S ++FGG+NGD +G+ +T A +L L+ +
Sbjct: 182 AALASGFAVVLLLKAY-----SEKHFGGVNGDVIGSANCLTFAASLSALTIA 228
>gi|11497658 cobalamin (5'-phosphate) synthase (cobS-1) [Archaeoglobus fulgidus]
>gi|7430168|pir||E69254 cobalamin (5'-phosphate)
synthase (cobS-1) homolog - Archaeoglobus fulgidus
>gi|2650615|gb|AAB91192.1| (AE001104) cobalamin
(5'-phosphate) synthase (cobS-1) [Archaeoglobus
fulgidus]
Length = 265
Score = 119 bits (295), Expect = 3e-26
Identities = 81/229 (35%), Positives = 120/229 (52%), Gaps = 15/229 (6%)
Query: 1 MRNILPFLTRIPVKGDFEKARNELWAFPLVSL-VSSIIPIAILYLRIPLANVLALLSLYF 59
+R+ L FLT +PVKGD + R LW F V + + S+I I + L + LY
Sbjct: 46 LRSSLGFLTTLPVKGDVDVLRRNLWVFSFVGIFIGSVISIPAV-----LGFWFLCVLLYV 100
Query: 60 VI-GLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPF 118
I G+ H+DGLAD+ D ERK A+KDLN G G + V + YS +
Sbjct: 101 AIEGVNHIDGLADFGDAFFAP--EERKKVAIKDLNLGTGGAVFLCVYFLILFYSFQRVSA 158
Query: 119 YAIYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDP 178
+ I +++ +KFSMLL L T KP QG+ + ME R + IG L L +V+ P
Sbjct: 159 FYIIFSQVLAKFSMLLLLTTSKPAWQGMTGFMMEFARKRDVVIG-----SLPLLLVVLKP 213
Query: 179 SALFGVM-GLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILSF 226
A+F ++ + + V R + E FGG++GD +GA + AG+L++ F
Sbjct: 214 LAVFPLLFAITISLLVKRYAEEKFGGVSGDVVGASNCLVFAGSLLVCYF 262
>pir||E64479 cobalamin (5'-phosphate) synthase - Methanococcus jannaschii
>gi|1592086|gb|AAB99447.1| (U67584) cobalamin
(5'-phosphate) synthase (cobS) [Methanococcus
jannaschii]
Length = 258
Score = 103 bits (255), Expect = 2e-21
Identities = 75/238 (31%), Positives = 121/238 (50%), Gaps = 13/238 (5%)
Query: 4 ILPFLTRIPV---KGDFEKARNELWAFPLVSLVSSIIPIAILYL---RIP--LANVLALL 55
+L F TRIP+ DFE N + L+ V I + + Y+ +P L+ VL L
Sbjct: 12 LLSFFTRIPIYVEDFDFENIANYFYLIILIGYVFGIFSLILGYIFSFLLPNFLSAVLILF 71
Query: 56 SLYFVIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLS- 114
+ ++ G H+DGL D+ DG M GD+ +K+ AMKD G GV + + V SLS
Sbjct: 72 FIEYLNGFHHIDGLIDFGDGWMAVGDKRKKLMAMKDRYIGCGGVVFAIFFNLMAVISLSY 131
Query: 115 MLPFYAIY--IAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLY--VLLY 170
+L +Y + E+ +K ML PL +G G YF++ + + L IG++L +LL
Sbjct: 132 ILDINILYLLVGEVCAKLGMLSCSTFGNPLIEGTGRYFVKKADEKFLTIGIILSLPLLLI 191
Query: 171 LPVVIYDPSALFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILSFSL 228
+ + + ++ + +++ +FGG+NGD LGA EITR L+ + S+
Sbjct: 192 FSGIERKIVIIAIITTIITGLCMAKIAKRHFGGVNGDVLGASNEITRVVVLLSIIASI 249
>emb|CAC12207.1| (AL445066) cobalamin synthase related protein [Thermoplasma
acidophilum]
Length = 255
Score = 98.3 bits (241), Expect = 7e-20
Identities = 69/234 (29%), Positives = 130/234 (55%), Gaps = 16/234 (6%)
Query: 1 MRNILPFLTRIPVKGDFEKARNELWAF-PLVSLVSSIIP----IAILYLRIPLANVLALL 55
+R+ F T IP+K + ++ L A+ PLV+L + + +AI + LA+ +++
Sbjct: 4 LRSAFSFFTIIPIKSELDE---HLIAYVPLVALFDAALAASLYVAIYGISKLLASFISVS 60
Query: 56 SLYFVIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSM 115
++Y V GL H+D +AD D +M++ +R R + +D + G GVF ++ V L + SLS
Sbjct: 61 AIYIVNGLNHVDAVADAGDAMMIR-NRSRIREVFEDHDVGAGGVFTLIFVYLLALISLSS 119
Query: 116 LPFY----AIYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYL 171
+ Y +I +AE SK M++ L +PL QG+G+ F++ + + ++ V +V++ +
Sbjct: 120 MDLYIGIFSIILAEFLSKSMMMITLHRSRPLFQGIGSLFID-LYRKHDSLYTVEFVVIPI 178
Query: 172 PVVIYDPSALFGVMGLVFAWYVI--RLSLENFGGINGDCLGAMAEITRAGTLVI 223
+ + +++ + L F ++I + FGGINGD G + E+ R+ L+I
Sbjct: 179 VLALLSRASIMISVALAFLIFIIVKMAVIRRFGGINGDLAGFIGELGRSIFLMI 232
>gb|AAK43328.1| Cobalamin synthase related protein [Sulfolobus solfataricus]
Length = 253
Score = 81.5 bits (198), Expect = 8e-15
Identities = 60/218 (27%), Positives = 108/218 (49%), Gaps = 23/218 (10%)
Query: 7 FLTRIPVKGD--FEKARNELWAFPLV-----SLVSSIIPIAILYLRIPLANVLALLSLYF 59
F T IPVK E+ + P++ L+ S+ + + + L ++ L +
Sbjct: 12 FFTAIPVKSSASLEEIAESSYISPIIVGISLGLIESVAYLILYRILGELTGIVLLGIIEL 71
Query: 60 VIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPF- 118
+ G HLDGL D D +M++G+RE+KIKA+KD+ G G+ ++V L +Q+ +L L F
Sbjct: 72 LRGFNHLDGLLDLGDALMIRGNREKKIKALKDVEVGSGGIGLLLVYLSIQIVALLKLDFS 131
Query: 119 -YAIYIAELNSKFSMLLG---LATKKPLGQ-GLGAYFMEGMNGRQLAIGVVLYVLLYLPV 173
Y I+ ++ SM L L+T P+ + LG F + + G+ + +L +P
Sbjct: 132 LYTIFYLISSNVLSMSLSLYILSTISPIPESNLGRIFHDKLKGKS-----TILLLELIPF 186
Query: 174 VIYDPSALFGVMGLVFAWYVIRLSLENFGGINGDCLGA 211
+ +L+ V+ + + ++ + GG +GD GA
Sbjct: 187 I-----SLYNVIVFIIFYMIMYKICGSLGGSSGDIAGA 219
>sp|Q05602|COBS_SALTY COBALAMIN [5'-PHOSPHATE] SYNTHASE >gi|154438|gb|AAA27270.1|
(L12006) cobalamin synthase [Salmonella typhimurium]
Length = 247
Score = 81.1 bits (197), Expect = 1e-14
Identities = 74/240 (30%), Positives = 116/240 (47%), Gaps = 23/240 (9%)
Query: 4 ILPFLTRIPVKG------DFEKARNELWAFPLVSL----VSSIIPIAIL-YLRIPLANVL 52
+L F++R+PV DFE+ + FP + L VS +I I + + IPLA +
Sbjct: 8 MLAFISRLPVPSRRSQGLDFEQYSRGIVMFPFIGLILGGVSGLIFILLQPWCGIPLAALF 67
Query: 53 ALLSLYFVIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYS 112
+L+L + G HLDGLAD DGI RER ++ M+D G G A++ VL ++
Sbjct: 68 CILALALLTGGFHLDGLADTCDGIFSARRRERMLEIMRDSRLGTHGGLALIFVLLAKILV 127
Query: 113 LSML-----PFYAIYIA--ELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVL 165
+S L P A A ++LL + +GLG F+ ++GRQ I + L
Sbjct: 128 VSELALRGTPMLAALAAACAAGRGSAVLLMYRHRYAREEGLGNVFIGKVSGRQTCITLGL 187
Query: 166 YVLLYLPVVIYDPSALFGVMGLVFAWYVI-RLSLENFGGINGDCLGAMAEITRAGTLVIL 224
V++ V++ L ++ A +++ +L GG GD LGA E+ G L+ L
Sbjct: 188 AVIV-ATVLLPGMQGLAAMVVTCAAIFILGQLLKRTLGGQTGDTLGAAIEL---GELIFL 243
>pir||G83486 cobalamin (5'-phosphate) synthase PA1281 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947215|gb|AAG04670.1|AE004557_11 (AE004557)
cobalamin (5'-phosphate) synthase [Pseudomonas
aeruginosa]
Length = 245
Score = 79.2 bits (192), Expect = 4e-14
Identities = 79/243 (32%), Positives = 113/243 (45%), Gaps = 32/243 (13%)
Query: 5 LPFLTRIPVKGDF----EKARNELWAFPLVSLVSSIIPIAI---LYLRIPLANVLALLSL 57
L FLTR+PV+ E+ + +PLV ++ ++ A L PL LLSL
Sbjct: 12 LQFLTRLPVRLSAMPTPEQFGRAVLCYPLVGVLIGVVLYAAARSLDGTPPLLQAALLLSL 71
Query: 58 YFVI-GLLHLDGLADWADG-IMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSM 115
+ + G LHLDGLAD AD + GDRER + MKD +G V +V+VL L+ +L+
Sbjct: 72 WVALSGALHLDGLADMADAWVGGLGDRERTLAIMKDPRSGPVAVVVLVLVLLLKFSALAA 131
Query: 116 L----PFYAIYIAELNSKFSM-LLGLATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLY 170
L + +A ++ S+ LL L T GLG E + R L +
Sbjct: 132 LLGQGEAGLLPLAPWLARSSLPLLFLTTPYARPGGLGQAIAEHLPARSLP---------W 182
Query: 171 LPVVIYDPSALFGVMGL--------VFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLV 222
+ V + + FG+ GL +FAW R L GG GD GA+ E+T LV
Sbjct: 183 VLGVSFGLALAFGLAGLLALLVTLMLFAWLRSRF-LARLGGTTGDTAGALVELTECAVLV 241
Query: 223 ILS 225
L+
Sbjct: 242 ALA 244
>sp|P36561|COBS_ECOLI COBALAMIN [5'-PHOSPHATE] SYNTHASE >gi|7445489|pir||G64963 cobalamin
(5'-phosphate) synthase - Escherichia coli
>gi|1736653|dbj|BAA15809.1| (D90837) Cobalamin
(5'-phosphate) synthase. [Escherichia coli]
>gi|1736659|dbj|BAA15814.1| (D90838) Cobalamin
(5'-phosphate) synthase. [Escherichia coli]
>gi|1788301|gb|AAC75053.1| (AE000291) cobalamin
5'-phosphate synthase [Escherichia coli K12]
Length = 247
Score = 78.0 bits (189), Expect = 9e-14
Identities = 71/243 (29%), Positives = 114/243 (46%), Gaps = 29/243 (11%)
Query: 4 ILPFLTRIPVKG------DFEKARNELWAFPLVSLV-SSIIPIAILYLRI----PLANVL 52
+L F+TR+PV DFE + FPL+ L+ +I + + L+ PLA +
Sbjct: 8 MLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAISGLVFMVLQAWCGAPLAALF 67
Query: 53 ALLSLYFVIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYS 112
++L L + G HLDGLAD DG+ R+R ++ M+D G G A++ V+ ++
Sbjct: 68 SVLVLVLMTGGFHLDGLADTCDGVFSARSRDRMLEIMRDSRLGTHGGLALIFVVLAKILV 127
Query: 113 LSMLPFYA-IYIAELNSKFSMLLGLAT------KKPLGQGLGAYFMEGMNGRQLAIGVVL 165
LS L +A L + ++ G A + +GLG F+ ++GRQ + + L
Sbjct: 128 LSELALRGESILASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTCVTLGL 187
Query: 166 YVLLYLPVVIYDPSALFGVMGLVFAWYVI----RLSLENFGGINGDCLGAMAEITRAGTL 221
++ V++ + GV +V I +L GG GD LGA E+ G L
Sbjct: 188 -AAIFAAVLL---PGMHGVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIEL---GEL 240
Query: 222 VIL 224
V L
Sbjct: 241 VFL 243
>gb|AAA78907.1| (U33333) cobalamin synthase [Escherichia coli]
Length = 247
Score = 77.6 bits (188), Expect = 1e-13
Identities = 70/243 (28%), Positives = 111/243 (44%), Gaps = 29/243 (11%)
Query: 4 ILPFLTRIPVKG------DFEKARNELWAFPLVSLVSSIIPIAIL-----YLRIPLANVL 52
+L F+TR+PV DFE + FPL+ L+ I + + PLA +
Sbjct: 8 MLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAIRRLVFMVLQAWCGAPLAALF 67
Query: 53 ALLSLYFVIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYS 112
++L L + G HLDGLAD DG+ R+R ++ M+D G G A++ V+ ++
Sbjct: 68 SVLVLVLMTGGFHLDGLADTCDGVFSARSRDRMLEIMRDSRLGTHGGLALIFVVLAKILV 127
Query: 113 LSMLPFYA-IYIAELNSKFSMLLGLAT------KKPLGQGLGAYFMEGMNGRQLAIGVVL 165
LS L +A L + ++ G A + +GLG F+ ++GRQ + + L
Sbjct: 128 LSELALRGESILASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTCVTLGL 187
Query: 166 YVLLYLPVVIYDPSALFGVMGLVFAWYVI----RLSLENFGGINGDCLGAMAEITRAGTL 221
++ V++ + GV +V I +L GG GD LGA E+ G L
Sbjct: 188 -AAIFAAVLL---PGMHGVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIEL---GEL 240
Query: 222 VIL 224
V L
Sbjct: 241 VFL 243
>pir||H75576 cobalamin synthase - Deinococcus radiodurans (strain R1)
>gi|6460693|gb|AAF12398.1|AE001863_23 (AE001863)
cobalamin synthase [Deinococcus radiodurans]
Length = 269
Score = 71.8 bits (173), Expect = 7e-12
Identities = 74/236 (31%), Positives = 113/236 (47%), Gaps = 28/236 (11%)
Query: 5 LPFLTRIPVK-------GDFEKARNELWAFPLVSLVSSIIPIAILYLRIPLA-NVLALLS 56
L FLT +P+ GDF +A +PL + +LYL +PL V+A L
Sbjct: 40 LAFLTTLPLPHVRDVQPGDFARASAY---YPLAGYAVGGLVAGLLYLNVPLPPGVVAALG 96
Query: 57 LYFVIGL---LHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSL 113
+ +GL LH DGL D AD + E+++ +KD++ G G+ V+ L L ++SL
Sbjct: 97 VGLWLGLTGMLHFDGLVDSADALFAMKSPEQRLDILKDVHVGAFGLATGVLALLL-LWSL 155
Query: 114 --SMLPFYAIYIAELNSKFSMLLGL-ATKKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLY 170
+ LP+YA +A + ++ +L+ + A + LGA +G G LA L LL
Sbjct: 156 LGAGLPWYAPLVAAVVARMVVLMPMNAYPAARQESLGAQSRQGRWG--LAFLFALPALLL 213
Query: 171 LPVVIYDPSALFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILSF 226
+ AL GV LV AW RL GG++GD G + + L++L F
Sbjct: 214 PHAWLAALVALLGVT-LVAAWAARRLG----GGLSGDVYGLLIVVAE---LLVLGF 261
>pir||T03519 cobalamin (5'-phosphate) synthase homolog - Rhodobacter capsulatus
>gi|3128320|gb|AAC16172.1| (AF010496) Cobalamin
[Rhodobacter capsulatus]
Length = 255
Score = 70.2 bits (169), Expect = 2e-11
Identities = 73/243 (30%), Positives = 112/243 (46%), Gaps = 30/243 (12%)
Query: 8 LTRIPVKGDFEKA---RNELWAFPLVSLV----SSIIPIAILYLRIP--LANVLALLSLY 58
LTR+P+ + A +WA+PL LV S++ A+L L +P LA LA+
Sbjct: 20 LTRLPMPRLADPAPTLAQSVWAYPLAGLVVGAISALALFAMLALGLPPALAAGLAVTLQV 79
Query: 59 FVIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVY------- 111
+ G LH DGLAD ADG + R+++ M+D G GV A+V+ L L+
Sbjct: 80 VITGALHEDGLADVADGFWGGREVARRLEIMRDSRIGSYGVTALVLSLGLRWQGVAALAA 139
Query: 112 ---SLSMLPFYAIYIAELNSKFSMLLGLATKKPLGQG---LGAYFMEGMNGRQLAIGVVL 165
+L+M + I + ++ GL +P G G GA + + G +AIG
Sbjct: 140 ASPALAMAGLIGLAILSRAACGVLMAGLPAARPDGMGRYASGAAWQRVIAGGAVAIGAAF 199
Query: 166 YVLLYLPVVIYDPSALFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTLVILS 225
L LPVV L V G + A + ++ GG GD LG ++ G ++L+
Sbjct: 200 G--LGLPVV-----PLLIVQGALVAGLAL-VARAKIGGQTGDVLGTAQQLAEIGGWLVLA 251
Query: 226 FSL 228
+L
Sbjct: 252 AAL 254
>pir||A69015 cobalamin (5'-phosphate) synthase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622214|gb|AAB85601.1| (AE000881) cobalamin
(5'-phosphate) synthase [Methanobacterium
thermoautotrophicum]
Length = 249
Score = 69.5 bits (167), Expect = 4e-11
Identities = 67/250 (26%), Positives = 114/250 (44%), Gaps = 28/250 (11%)
Query: 1 MRNILPFLTRIPVKGD--FEKARNELWAFPLVSLVSSI------IPIAILYLRIPLANVL 52
+R ++ F T +P+K + E + +PLV + + + ++++ +A V
Sbjct: 7 LRGLISFSTVLPLKSEASIEDIASLTLHWPLVGALIGVAVGSAGVAASLVFPGAVVACVA 66
Query: 53 ALLSLYFVIGLLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYS 112
+++F G HLDGL D D +M G ERKI+ M+D G G+ +++V + +
Sbjct: 67 YGFAIWFT-GFHHLDGLIDMGDALMSHGSFERKIEIMRDPRIGTGGLGLLLIVSSTTIAA 125
Query: 113 LSMLP----FYAIYIAELNSKFSMLLGLATKKPLGQGLGAYFMEGMNGRQLAIGVV---- 164
+ LP F + I E+++K + +PL G G +F+ M R G+V
Sbjct: 126 IYSLPQGVLFQGLLIGEVSAKVCLTGCARVSRPLDGGTGRHFI--MASRSPFTGMVWIFW 183
Query: 165 ---LYVLLYLPVVIYDPSALFGVMGLVFAWYVIRLSLENFGGINGDCLGAMAEITRAGTL 221
Y+L +P + S V+ VF V R NF GD LGA E+ R +L
Sbjct: 184 AVAAYLLAGVPGAV---SVAVAVLSGVFIGLVAR---RNFYWSTGDVLGASNEVGRMMSL 237
Query: 222 VILSFSLCFT 231
+ L ++ T
Sbjct: 238 LGLLAAIRLT 247
>gb|AAA56875.1| (L25054) cobalamine (5'-phosphate) synthase; CobS [Escherichia
coli]
Length = 217
Score = 69.1 bits (166), Expect = 5e-11
Identities = 61/214 (28%), Positives = 99/214 (45%), Gaps = 23/214 (10%)
Query: 27 FPLVSLVSSIIPIAIL-----YLRIPLANVLALLSLYFVIGLLHLDGLADWADGIMVKGD 81
FPL+ L+ I + + PLA + ++L L + G HLDGLAD DG+
Sbjct: 7 FPLIGLLLGAIRRLVFMVLQAWCGAPLAALFSVLVLVLMTGGFHLDGLADTCDGVFSARS 66
Query: 82 RERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPFYA-IYIAELNSKFSMLLGLAT-- 138
R+R ++ M+D G G A++ V+ ++ LS L +A L ++ ++ G A
Sbjct: 67 RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGESILASLAARCAVSRGTAALL 126
Query: 139 ----KKPLGQGLGAYFMEGMNGRQLAIGVVLYVLLYLPVVIYDPSALFGVMGLVFAWYVI 194
+ +GLG F+ ++GRQ + + L ++ V++ + GV +V I
Sbjct: 127 MYRHRYAREEGLGNVFIGKIDGRQTCVTLGL-AAIFAAVLL---PGMHGVTAMVVTMVAI 182
Query: 195 ----RLSLENFGGINGDCLGAMAEITRAGTLVIL 224
+L GG GD LGA E+ G LV L
Sbjct: 183 FILGQLLKRTLGGQTGDTLGAAIEL---GELVFL 213
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.329 0.147 0.437
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79621146
Number of Sequences: 2977
Number of extensions: 3153695
Number of successful extensions: 9906
Number of sequences better than 1.0e-10: 16
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 9879
Number of HSP's gapped (non-prelim): 16
length of query: 232
length of database: 189,106,746
effective HSP length: 50
effective length of query: 182
effective length of database: 159,182,396
effective search space: 28971196072
effective search space used: 28971196072
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.8 bits)
S2: 164 (68.3 bits)