BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2345 (nadA) DE:QUINOLINATE SYNTHETASE A
(308 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75186 quinolinate synthetase A PAB2345 - Pyrococcus abyssi... 616 e-175
pir||B71219 probable quinolinate synthetase - Pyrococcus horikos... 547 e-155
sp|Q57850|NADA_METJA PROBABLE QUINOLINATE SYNTHETASE A >gi|21292... 335 4e-91
pir||C69111 quinolinate synthetase - Methanobacterium thermoauto... 320 1e-86
pir||A72227 quinolinate synthetase A - Thermotoga maritima (stra... 319 2e-86
gi|11500029 quinolinate synthetase (nadA) [Archaeoglobus fulgidus] 282 4e-75
pir||H70462 quinolinate synthetase A - Aquifex aeolicus >gi|2984... 276 3e-73
gb|AAK41269.1| Quinolinate synthetase (nadA) [Sulfolobus solfata... 271 7e-72
gi|11467328 quinolinate synthetase [Cyanophora paradoxa] >gi|400... 235 5e-61
gb|AAF35373.1|AF225957_1 (AF225957) quinolinate synthetase [Syne... 231 1e-59
pir||H82620 quinolinate synthetase A XF1923 [imported] - Xylella... 229 2e-59
sp|P74578|NADA_SYNY3 QUINOLINATE SYNTHETASE A >gi|7438204|pir||S... 227 1e-58
pir||S72703 quinolinate synthetase nadA - Mycobacterium leprae >... 212 6e-54
pir||D70543 probable nadA protein - Mycobacterium tuberculosis (... 208 5e-53
gb|AAB50414.1| (U90899) quinolinate synthetase [Ehrlichia chaffe... 199 2e-50
sp|P24519|NADA_SALTY QUINOLINATE SYNTHETASE A >gi|96809|pir||C37... 184 9e-46
sp|P11458|NADA_ECOLI QUINOLINATE SYNTHETASE A >gi|7428533|pir||S... 178 7e-44
pir||E82151 quinolinate synthetase A VC1833 [imported] - Vibrio ... 177 2e-43
pir||E83519 quinolinate synthetase A PA1004 [imported] - Pseudom... 170 2e-41
pir||B81204 quinolinate synthetase A NMB0394 [imported] - Neisse... 166 2e-40
pir||C81780 quinolinate synthetase A NMA2090 [imported] - Neisse... 166 3e-40
gb|AAB50416.1| (U90901) quinolinate synthetase [Ehrlichia muris] 164 9e-40
emb|CAA31216.1| (X12713) nadA gene product (AA 1 - 280) [Escheri... 156 3e-37
pir||D64689 quinolinate synthetase A - Helicobacter pylori (stra... 152 7e-36
pir||A71828 quinolinate synthetase - Helicobacter pylori (strain... 151 1e-35
gb|AAG20079.1| (AE005087) quinolinate synthetase; NadA [Halobact... 144 1e-33
pir||E69663 quinolinate synthetase nadA - Bacillus subtilis >gi|... 143 2e-33
emb|CAB75321.1| (Y15896) quinolinate synthetase A [Bacillus subt... 143 2e-33
dbj|BAB04939.1| (AP001511) quinolinate synthetase [Bacillus halo... 140 2e-32
gb|AAB50415.1| (U90900) quinolinate synthetase [Ehrlichia canis] 95 1e-18
emb|CAC12800.1| (AL445343) putative quinolinate synthetase (frag... 83 3e-15
dbj|BAB09392.1| (AB024031) gb|AAF26953.1~gene_id:K6A12.7~similar... 73 5e-12
pir||T35544 probable quinolinate synthetase - Streptomyces coeli... 69 6e-11
>pir||A75186 quinolinate synthetase A PAB2345 - Pyrococcus abyssi (strain Orsay)
>gi|5457445|emb|CAB48936.1| (AJ248283) QUINOLINATE
SYNTHETASE A [Pyrococcus abyssi]
Length = 308
Score = 616 bits (1571), Expect = e-175
Identities = 308/308 (100%), Positives = 308/308 (100%)
Query: 1 MSNSIMGVEMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDAD 60
MSNSIMGVEMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDAD
Sbjct: 1 MSNSIMGVEMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDAD 60
Query: 61 VIVFAGVDFMAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVN 120
VIVFAGVDFMAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVN
Sbjct: 61 VIVFAGVDFMAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVN 120
Query: 121 STAETKAYADVTVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCY 180
STAETKAYADVTVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCY
Sbjct: 121 STAETKAYADVTVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCY 180
Query: 181 VHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHDEWVVFTE 240
VHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHDEWVVFTE
Sbjct: 181 VHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHDEWVVFTE 240
Query: 241 REMVYRLKKLYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRA 300
REMVYRLKKLYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRA
Sbjct: 241 REMVYRLKKLYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRA 300
Query: 301 IERMLEMS 308
IERMLEMS
Sbjct: 301 IERMLEMS 308
>pir||B71219 probable quinolinate synthetase - Pyrococcus horikoshii
>gi|3256398|dbj|BAA29081.1| (AP000001) 300aa long
hypothetical quinolinate synthetase [Pyrococcus
horikoshii]
Length = 300
Score = 547 bits (1395), Expect = e-155
Identities = 265/299 (88%), Positives = 286/299 (95%)
Query: 10 MDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDF 69
MD+VEEIL+LKEERNA+ILAHNYQLPEVQDIADFIGDSLELAR+AT+VDADVIVFAGVDF
Sbjct: 1 MDLVEEILRLKEERNAIILAHNYQLPEVQDIADFIGDSLELARRATRVDADVIVFAGVDF 60
Query: 70 MAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYA 129
MAETAKILNPDK VL+PSR ATCAMANMLKVEHI+EAKRKYPNAPVVLYVNSTAE KAYA
Sbjct: 61 MAETAKILNPDKVVLIPSREATCAMANMLKVEHILEAKRKYPNAPVVLYVNSTAEAKAYA 120
Query: 130 DVTVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIED 189
DVTVTSANAV++V KLD+DVVIFGPDKNLAHYVAKMTGKK+IPVP GHCYVHQKFT++D
Sbjct: 121 DVTVTSANAVEVVKKLDSDVVIFGPDKNLAHYVAKMTGKKIIPVPSKGHCYVHQKFTLDD 180
Query: 190 VERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHDEWVVFTEREMVYRLKK 249
VERAKKL+PNAKLM+HPECIPEVQEKADII STGGMIK AC DEWVVFTEREMVYRL+K
Sbjct: 181 VERAKKLHPNAKLMIHPECIPEVQEKADIIASTGGMIKRACEWDEWVVFTEREMVYRLRK 240
Query: 250 LYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIERMLEMS 308
LYP+KKFYPAREDA CIGMKAITLK+IYESL+DMKYKVEVP +IA KAR+AIERMLEMS
Sbjct: 241 LYPQKKFYPAREDAFCIGMKAITLKNIYESLKDMKYKVEVPEEIARKARKAIERMLEMS 299
>sp|Q57850|NADA_METJA PROBABLE QUINOLINATE SYNTHETASE A >gi|2129232|pir||G64350
quinolinate synthetase - Methanococcus jannaschii
>gi|1591113|gb|AAB98397.1| (U67493) quinolinate
synthetase (nadA) [Methanococcus jannaschii]
Length = 307
Score = 335 bits (850), Expect = 4e-91
Identities = 172/307 (56%), Positives = 226/307 (73%), Gaps = 7/307 (2%)
Query: 8 VEMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGV 67
+ MDIVE I KLKEE+NAVILAHNYQ E+Q IADF+GDSLEL KA + DAD+IVF GV
Sbjct: 1 MSMDIVERINKLKEEKNAVILAHNYQPKEIQKIADFLGDSLELCIKAKETDADIIVFCGV 60
Query: 68 DFMAETAKILNPDKTVLLPSRRAT-CAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETK 126
DFM E+AKILNP+K VL+P T C MA+ L E I + + YP AP+V+YVN+TAETK
Sbjct: 61 DFMGESAKILNPEKKVLMPEIEGTQCPMAHQLPPEIIKKYRELYPEAPLVVYVNTTAETK 120
Query: 127 AYADVTVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFT 186
A AD+T TSANA ++V+ LDAD V+FGPD NLA+YV K T KKVI +P G CYVH+KFT
Sbjct: 121 ALADITCTSANADRVVNSLDADTVLFGPDNNLAYYVQKRTDKKVIAIPEGGGCYVHKKFT 180
Query: 187 IEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHD--EWVVFTEREMV 244
I+D++R K YPNAK+++HPEC PE+Q+ AD I ST G+++ D E+++ TE M+
Sbjct: 181 IDDLKRVKSKYPNAKVLIHPECSPELQDNADYIASTSGILRIVLESDDEEFIIGTEVGMI 240
Query: 245 YR----LKKLYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRA 300
R L+KL +K P R+DAIC MK ITL+ I + L + +Y++++ ++I EKA++A
Sbjct: 241 NRLEIELEKLGKKKTLIPLRKDAICHEMKRITLEKIEKCLLEERYEIKLEKEIIEKAQKA 300
Query: 301 IERMLEM 307
IERML +
Sbjct: 301 IERMLRI 307
>pir||C69111 quinolinate synthetase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622961|gb|AAB86293.1| (AE000936)
quinolinate synthetase [Methanobacterium
thermoautotrophicum]
Length = 304
Score = 320 bits (811), Expect = 1e-86
Identities = 161/297 (54%), Positives = 218/297 (73%), Gaps = 4/297 (1%)
Query: 15 EILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDA-DVIVFAGVDFMAET 73
+IL+LK+E+NA+ILAHNYQ E+Q+IADF GDSLEL +A++++ D++VF GVDFMAET
Sbjct: 8 DILRLKKEKNAIILAHNYQSREIQEIADFKGDSLELCIEASRIEGKDIVVFCGVDFMAET 67
Query: 74 AKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTV 133
A ILNPDK +L+P R A C MA+ML E + A+++YP+A VVLYVN+ AE KA AD+
Sbjct: 68 AYILNPDKKILIPDRGAECPMAHMLSAEDVRMARKRYPDAAVVLYVNTLAEAKAEADILC 127
Query: 134 TSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERA 193
TSANAV++V LD D+V+FGPD+NLA YV + T K +IP+P GHCYVH+ FT DV A
Sbjct: 128 TSANAVRVVESLDEDLVLFGPDRNLAWYVQEHTDKTIIPIPEEGHCYVHKMFTAGDVMAA 187
Query: 194 KKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHD--EWVVFTEREMVYRLKKLY 251
K+ YP A+L++HPEC PEVQE AD I+STGGM++ D +++ TE +M R+ L
Sbjct: 188 KEKYPEAELLIHPECDPEVQELADHILSTGGMLRRVLESDAESFIIGTEVDMTTRI-SLE 246
Query: 252 PEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIERMLEMS 308
+KK P E+AIC MK TL+ + SL + ++ V VP +IA +ARRA+ERM+ +S
Sbjct: 247 SDKKTIPLLEEAICENMKLHTLEKVKNSLINEEFVVTVPDEIARRARRAVERMIRVS 303
>pir||A72227 quinolinate synthetase A - Thermotoga maritima (strain MSB8)
>gi|4982218|gb|AAD36711.1|AE001807_2 (AE001807)
quinolinate synthetase A [Thermotoga maritima]
Length = 298
Score = 319 bits (809), Expect = 2e-86
Identities = 162/298 (54%), Positives = 219/298 (73%), Gaps = 4/298 (1%)
Query: 12 IVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFMA 71
+V+EILKLK+E+ +ILAHNYQ+PE+QDIADF+GDSL+LARKA ++ I+F GVDFMA
Sbjct: 1 MVDEILKLKKEKGYIILAHNYQIPELQDIADFVGDSLQLARKAMELSEKKILFLGVDFMA 60
Query: 72 ETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADV 131
E KILNPDK V++P R ATC MAN L E I E + K+P+APVVLYVNST+E K ADV
Sbjct: 61 ELVKILNPDKKVIVPDRSATCPMANRLTPEIIREYREKFPDAPVVLYVNSTSECKTLADV 120
Query: 132 TVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVE 191
TSANAV++V KLD+ VVIFGPD+NL YVA+ TGKKVI +P NGHC VHQ F E ++
Sbjct: 121 ICTSANAVEVVKKLDSSVVIFGPDRNLGEYVAEKTGKKVITIPENGHCPVHQ-FNAESID 179
Query: 192 RAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGM--IKNACLHDEWVVFTEREMVYRLKK 249
+K YP+AK++VHPEC V++KAD + STG M I +V+ TE M+++LKK
Sbjct: 180 AVRKKYPDAKVIVHPECPKPVRDKADYVGSTGQMEKIPEKDPSRIFVIGTEIGMIHKLKK 239
Query: 250 LYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIERMLEM 307
+P+++F P E A+C+ MK TL++ +L+ ++V +P+++ EKA++ I RM E+
Sbjct: 240 KFPDREFVPL-EMAVCVNMKKNTLENTLHALQTESFEVILPKEVIEKAKKPILRMFEL 296
>gi|11500029 quinolinate synthetase (nadA) [Archaeoglobus fulgidus]
Length = 300
Score = 282 bits (713), Expect = 4e-75
Identities = 152/295 (51%), Positives = 203/295 (68%), Gaps = 5/295 (1%)
Query: 15 EILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFMAETA 74
+I +LK ++NAVILAHNYQ+ +Q +ADF+GDSLEL+ A VDAD+I+F GVDFMAETA
Sbjct: 8 DIERLKRQKNAVILAHNYQILPIQGVADFVGDSLELSMAAKDVDADIILFCGVDFMAETA 67
Query: 75 KILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTVT 134
ILNPDK VL+PS A C MA + E + +AK KY NAP V YVN+ AETKA ADV T
Sbjct: 68 AILNPDKKVLIPSTEAICPMAMQIDAEMVKKAKEKY-NAPFVAYVNTHAETKAVADVCCT 126
Query: 135 SANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERAK 194
SAN K+V LDA+ V+ GPD NLA Y A+ TGK+VI VP G+C VHQ FT +DV A+
Sbjct: 127 SANVAKVVENLDAERVLLGPDANLAWYAAEKTGKEVIAVPQYGNCCVHQSFTAKDVLTAR 186
Query: 195 KLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHD--EWVVFTEREMVYRLKKLYP 252
+ +P+A ++VHPEC PEVQ+ AD + ST M++ D + ++ TE ++ RL++
Sbjct: 187 EKHPDATIIVHPECRPEVQKLADFVGSTSQMVRFVEQSDAEKVIIGTEIGLIERLRQ-QS 245
Query: 253 EKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIERMLEM 307
+K P +E ++C MK T+ + ++L + + V V IAEKARRAIERM E+
Sbjct: 246 DKTILPLKE-SVCRAMKRNTMDGVVKALVEERNVVRVDEKIAEKARRAIERMFEL 299
>pir||H70462 quinolinate synthetase A - Aquifex aeolicus
>gi|2984153|gb|AAC07687.1| (AE000761) quinolinate
synthetase A [Aquifex aeolicus]
Length = 322
Score = 276 bits (698), Expect = 3e-73
Identities = 146/305 (47%), Positives = 210/305 (67%), Gaps = 8/305 (2%)
Query: 11 DIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFM 70
++ +E+ +L +E+NAVILAH YQ PEVQDIADF+GDSLELARKA++ DAD+IVF GV FM
Sbjct: 19 ELQKEVRRLAKEKNAVILAHYYQRPEVQDIADFVGDSLELARKASQTDADIIVFCGVRFM 78
Query: 71 AETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYAD 130
ETAKI+NP+K VL P+ + C MA+M+ + + E + K+P+A V Y+N+TA+ KA D
Sbjct: 79 CETAKIVNPEKKVLHPNPESGCPMADMITAKQVRELREKHPDAEFVAYINTTADVKAEVD 138
Query: 131 VTVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDV 190
+ VTSANA KI+ KL+A ++F PD+ L ++VAK +K + G C H +FT +++
Sbjct: 139 ICVTSANAPKIIKKLEAKKIVFLPDQALGNWVAKQVPEKEF-IIWKGFCPPHFEFTYKEL 197
Query: 191 ERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHD--EWVVFTEREMVYRLK 248
E+ K++YP+AK+ VHPEC P V E AD + ST ++K A D +V TE + Y L+
Sbjct: 198 EKLKEMYPDAKVAVHPECHPRVIELADFVGSTSQILKYATSVDAKRVIVVTEVGLKYTLE 257
Query: 249 KLYPEKKF-YPARED----AICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIER 303
K+ P K++ +P + C MK ITL +YE+L++ +V +P+DI E+ARR IER
Sbjct: 258 KINPNKEYIFPQSMNYCGTVYCCTMKGITLPKVYETLKNEINEVTLPKDIIERARRPIER 317
Query: 304 MLEMS 308
MLE+S
Sbjct: 318 MLELS 322
>gb|AAK41269.1| Quinolinate synthetase (nadA) [Sulfolobus solfataricus]
Length = 311
Score = 271 bits (686), Expect = 7e-72
Identities = 148/305 (48%), Positives = 198/305 (64%), Gaps = 8/305 (2%)
Query: 11 DIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFM 70
+++ +I LK E+NA+IL HNY VQ ++DF GDS +LA KA K +A +I+FAGV FM
Sbjct: 6 ELLSQIKNLKTEKNAIILGHNYMEYSVQLVSDFTGDSYDLAVKAMKTNAKIILFAGVYFM 65
Query: 71 AETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYAD 130
AE A LNP+K VL P A C +++ L V+ + E K KYPNAPVVLY+N++ KA AD
Sbjct: 66 AEQASALNPNKKVLSPDPNAGCTLSDSLDVKTLQEYKEKYPNAPVVLYINTSIYAKALAD 125
Query: 131 VTVTSANAVKIVSKLDADVVIFGPDKNLAHYV-AKMTGKKVIPVPPNGHCYVHQKFTIED 189
VTS+ AVK+V KL+AD ++FGPD NLA+YV K+ KK+I VPPNG C VH +T +
Sbjct: 126 YIVTSSTAVKVVQKLNADTILFGPDANLANYVQQKVPNKKIIKVPPNGRCIVHANYTKQL 185
Query: 190 VERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIK--NACLHDEWVVFTEREMVYRL 247
VE A+K YPNA LM HPE E+ E AD + ST MI+ ++E++V TE M+ L
Sbjct: 186 VELARKKYPNALLMAHPEAPLEILESADFVGSTNQMIQFSKENKNEEFIVATEIGMINAL 245
Query: 248 KKLYPEKKFYP-----AREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIE 302
K P KKFYP A A C M I L+ + SL + Y+V+VP DIAE+ +RA E
Sbjct: 246 KIKNPSKKFYPLVTTEACACARCPYMNMINLEKVKRSLEEEVYEVKVPEDIAERVKRAFE 305
Query: 303 RMLEM 307
+++
Sbjct: 306 NTMKL 310
>gi|11467328 quinolinate synthetase [Cyanophora paradoxa]
>gi|400324|sp|P31179|NADA_CYAPA QUINOLINATE SYNTHETASE A
>gi|7438205|pir||T06873 quinolinate synthetase A (EC
1.4.3.-) - Cyanophora paradoxa cyanelle
>gi|336640|gb|AAA65473.1| (M37111) quinolinate
synthetase [Cyanophora paradoxa]
>gi|1016129|gb|AAA81216.1| (U30821) quinolinate
synthetase [Cyanophora paradoxa]
>gi|228689|prf||1808319A quinolinate synthetase
[Cyanophora paradoxa]
Length = 329
Score = 235 bits (593), Expect = 5e-61
Identities = 129/306 (42%), Positives = 195/306 (63%), Gaps = 12/306 (3%)
Query: 12 IVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFMA 71
++ +I LK++ NA+ILAH YQ P++QD+ADF+GDSL LAR+A K +AD+IVFAGV FMA
Sbjct: 26 LINDIQTLKKDLNAIILAHYYQEPDIQDVADFLGDSLGLAREAAKTNADIIVFAGVHFMA 85
Query: 72 ETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADV 131
ETAKILNP+K VLLP A C++A+ E E K+ + + V+ Y+N +A KA +D+
Sbjct: 86 ETAKILNPEKMVLLPDLNAGCSLADSCPPEIFSEFKKAHSDHLVISYINCSASIKAMSDI 145
Query: 132 TVTSANAVKIVSKLD-ADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDV 190
TSANAV IV+K+ ++F PD+NL YV TG+ ++ P G C VH+ F+ + +
Sbjct: 146 ICTSANAVDIVNKIPLTQPILFAPDQNLGRYVISKTGRDLLLWP--GSCIVHETFSEKKI 203
Query: 191 ERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGM---IKNACLHDEWVVFTEREMVYRL 247
+ LYP A+++ HPEC P + + A+ I ST + +KN+ ++V TE +++++
Sbjct: 204 FEFQSLYPTAEVIAHPECEPTILKHANYIGSTTSLLQYVKNS-KKTTFIVITEPGIIHQM 262
Query: 248 KKLYPEKKF--YPAREDAI---CIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIE 302
KK PEK+F P C M+ TL+ +Y +++ ++E+P I A++ IE
Sbjct: 263 KKSCPEKQFLALPTVSGCACNECPHMRLNTLEKLYLAMKTRSPQIEIPESILLNAKKPIE 322
Query: 303 RMLEMS 308
RMLEMS
Sbjct: 323 RMLEMS 328
>gb|AAF35373.1|AF225957_1 (AF225957) quinolinate synthetase [Synechococcus PCC7942]
Length = 320
Score = 231 bits (582), Expect = 1e-59
Identities = 133/308 (43%), Positives = 193/308 (62%), Gaps = 13/308 (4%)
Query: 11 DIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFM 70
D+ I LK+E NAVILAH YQ +QD+AD+IGDSL L+R+A DADVIVFAGV FM
Sbjct: 15 DLPAAIAALKQELNAVILAHYYQEAAIQDVADYIGDSLGLSRQAAAADADVIVFAGVHFM 74
Query: 71 AETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYAD 130
AETAKILNP + VLLP A C++A+ E K +PN V+ Y+N TAE KA +D
Sbjct: 75 AETAKILNPQRQVLLPDLAAGCSLADSCPPEAFAAFKAAHPNHIVISYINCTAEIKALSD 134
Query: 131 VTVTSANAVKIVSKLDAD-VVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIED 189
+ TS+NAVKIV ++ D +IF PD+NL YV + TG+ + V +G C VH+ F+ +
Sbjct: 135 IICTSSNAVKIVQQIPVDQPIIFAPDRNLGRYVMQQTGRDL--VLWDGSCIVHETFSEQR 192
Query: 190 VERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHD---EWVVFTEREMVYR 246
+ + +P+A+++ HPEC V ++A I ST ++ N L+ E++V TE ++++
Sbjct: 193 LLELQARHPDAEIIAHPECETPVLDQARFIGSTTALL-NYSLNSPSREFIVVTEPGIIHQ 251
Query: 247 LKKLYPEKKFYPA-REDAICI-----GMKAITLKHIYESLRDMKYKVEVPRDIAEKARRA 300
+++ PEK F PA +D C M+ TL+ +Y +RD + ++++P + A R
Sbjct: 252 MQQAAPEKTFIPAPPQDTTCACNECPFMRLNTLEKLYLCMRDRRPEIQIPEETRLAALRP 311
Query: 301 IERMLEMS 308
IERML MS
Sbjct: 312 IERMLAMS 319
>pir||H82620 quinolinate synthetase A XF1923 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107023|gb|AAF84729.1|AE004012_3
(AE004012) quinolinate synthetase A [Xylella fastidiosa]
Length = 348
Score = 229 bits (579), Expect = 2e-59
Identities = 130/296 (43%), Positives = 180/296 (59%), Gaps = 7/296 (2%)
Query: 13 VEEILKLKEERNAVILAHNYQLPEV-QDIADFIGDSLELARKATKVDADVIVFAGVDFMA 71
+E I +LK +RNAVILAHNYQ PE+ +AD +GDSL LARKA VDADVIV AGV FMA
Sbjct: 55 IEAIFELKRKRNAVILAHNYQTPEIFHGVADIVGDSLALARKAIDVDADVIVLAGVHFMA 114
Query: 72 ETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADV 131
ETAK+LNP+KTVL+P A C++A + E + ++ YP P+V YVN++A KA +D+
Sbjct: 115 ETAKLLNPEKTVLIPDMEAGCSLAESITPEDVALLRQTYPGIPIVTYVNTSAAVKAASDI 174
Query: 132 TVTSANAVKIVSKLDADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVE 191
TS NA K+V L V+ PD+ LA VAK T ++I +GHC VH+ F+ D+
Sbjct: 175 CCTSGNAKKVVEALGVPKVLMIPDEYLARNVAKETEVQIISW--HGHCEVHELFSASDIL 232
Query: 192 RAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHD--EWVVFTEREMVYRLKK 249
+ ++ +P ++ HPEC P+V AD ST M V+ TE M +
Sbjct: 233 QLRENHPGVTVLAHPECPPDVVAAADFAGSTAAMSDYVTTKQPKRVVLLTECSMSDNIAV 292
Query: 250 LYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIERML 305
+P+ +F + +C MK ITL +I +L + +++V V IA ARRA+ERML
Sbjct: 293 HHPDVEFISSCN--LCPHMKRITLANIRTALEENRHEVTVDAKIAAPARRAVERML 346
>sp|P74578|NADA_SYNY3 QUINOLINATE SYNTHETASE A >gi|7438204|pir||S76773 hypothetical
protein - Synechocystis sp. (strain PCC 6803)
>gi|1653774|dbj|BAA18685.1| (D90916) quinolinate
synthetase [Synechocystis sp.]
Length = 318
Score = 227 bits (573), Expect = 1e-58
Identities = 129/306 (42%), Positives = 187/306 (60%), Gaps = 10/306 (3%)
Query: 11 DIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFM 70
D+V I LK+E NAVILAH YQ +QDIAD++GDSL L+++A DADVIVFAGV FM
Sbjct: 15 DLVGAIQSLKKELNAVILAHYYQEAAIQDIADYLGDSLGLSQQAASTDADVIVFAGVHFM 74
Query: 71 AETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYAD 130
AETAKILNP K VLLP A C++A+ E K+++P+ V+ Y+N TAE KA +D
Sbjct: 75 AETAKILNPHKLVLLPDLEAGCSLADSCPPREFAEFKQRHPDHLVISYINCTAEIKALSD 134
Query: 131 VTVTSANAVKIVSKLDAD-VVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIED 189
+ TS+NAVKIV +L D +IF PD+NL YV + TG+++ V G C VH+ F+
Sbjct: 135 IICTSSNAVKIVQQLPPDQKIIFAPDRNLGRYVMEQTGREM--VLWQGSCIVHETFSERR 192
Query: 190 VERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMI--KNACLHDEWVVFTEREMVYRL 247
+ K YP A+++ HPEC + AD I ST ++ E++V TE +++++
Sbjct: 193 LLELKTQYPQAEIIAHPECEKAILRHADFIGSTTALLNYSGKSQGKEFIVGTEPGIIHQM 252
Query: 248 KKLYPEKKFYPAREDA-----ICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIE 302
+KL P K+F P ++ C M+ TL+ +Y +++ ++ +P A + I+
Sbjct: 253 EKLSPSKQFIPLPNNSNCDCNECPYMRLNTLEKLYWAMQRRSPEITLPEATMAAALKPIQ 312
Query: 303 RMLEMS 308
RML MS
Sbjct: 313 RMLAMS 318
>pir||S72703 quinolinate synthetase nadA - Mycobacterium leprae
>gi|466791|gb|AAA17067.1| (U00010) nadA; quinolinate
synthetase, A protein; Lepb1170_C2_201 [Mycobacterium
leprae]
Length = 368
Score = 212 bits (533), Expect = 6e-54
Identities = 127/310 (40%), Positives = 187/310 (59%), Gaps = 21/310 (6%)
Query: 15 EILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFMAETA 74
EI +L R A +LAHNYQLP +QDIAD++GDSL L+R A +V + IVF GV FMAETA
Sbjct: 56 EIRRLTRLRGATVLAHNYQLPAIQDIADYVGDSLALSRIAAEVPEETIVFCGVHFMAETA 115
Query: 75 KILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTVT 134
KIL+P+KTVL+P +RA C++A+ + + + K ++P A VV YVN+TAE KA D+ T
Sbjct: 116 KILSPNKTVLIPDQRAGCSLADSITPDELCAWKDEHPGAAVVSYVNTTAEVKALTDICCT 175
Query: 135 SANAVKIVSKLD-ADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERA 193
S+NAV +V +D + V+F PD+ L +V ++TG+K + V G C+VH +++
Sbjct: 176 SSNAVDVVESIDPSREVLFCPDQFLGAHVRRVTGRKNVYV-WMGECHVHAGINGDELVDQ 234
Query: 194 KKLYPNAKLMVHPEC--------------IPEVQEKADIIVSTGGMIKNA--CLHDEWVV 237
+ P+A+L VHPEC P + K I+STGGM+ A + + +V
Sbjct: 235 ARANPDAELFVHPECGCSTSALYLAGEGAFPPDRVK---ILSTGGMLTAARQTQYRKILV 291
Query: 238 FTEREMVYRLKKLYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKA 297
TE M+Y+L++ PE F + A C MK IT + L + +V V +IA
Sbjct: 292 ATEVGMLYQLRRAAPEIDFRAVNDRASCKYMKMITPGALLRCLVEGTDEVHVDSEIAAAG 351
Query: 298 RRAIERMLEM 307
RR+++RM+E+
Sbjct: 352 RRSVQRMIEI 361
>pir||D70543 probable nadA protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2117243|emb|CAB09075.1| (Z95586) nadA [Mycobacterium
tuberculosis]
Length = 349
Score = 208 bits (525), Expect = 5e-53
Identities = 125/310 (40%), Positives = 184/310 (59%), Gaps = 21/310 (6%)
Query: 15 EILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFMAETA 74
EI +L R A +LAHNYQLP +QD+AD +GDSL L+R A + D IVF GV FMAETA
Sbjct: 37 EIRRLAHLRGATVLAHNYQLPAIQDVADHVGDSLALSRVAAEAPEDTIVFCGVHFMAETA 96
Query: 75 KILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTVT 134
KIL+P KTVL+P +RA C++A+ + + + K ++P A VV YVN+TA KA D+ T
Sbjct: 97 KILSPHKTVLIPDQRAGCSLADSITPDELRAWKDEHPGAVVVSYVNTTAAVKALTDICCT 156
Query: 135 SANAVKIVSKLDAD-VVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERA 193
S+NAV +V+ +D D V+F PD+ L +V ++TG+K + V G C+VH +++
Sbjct: 157 SSNAVDVVASIDPDREVLFCPDQFLGAHVRRVTGRKNLHVWA-GECHVHAGINGDELADQ 215
Query: 194 KKLYPNAKLMVHPEC--------------IPEVQEKADIIVSTGGMIKNA--CLHDEWVV 237
+ +P+A+L VHPEC P + K I+STGGM++ A + +V
Sbjct: 216 ARAHPDAELFVHPECGCATSALYLAGEGAFPAERVK---ILSTGGMLEAAHTTRARQVLV 272
Query: 238 FTEREMVYRLKKLYPEKKFYPAREDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKA 297
TE M+++L++ PE F + A C MK IT + L + +V V IA
Sbjct: 273 ATEVGMLHQLRRAAPEVDFRAVNDRASCKYMKMITPAALLRCLVEGADEVHVDPGIAASG 332
Query: 298 RRAIERMLEM 307
RR+++RM+E+
Sbjct: 333 RRSVQRMIEI 342
>gb|AAB50414.1| (U90899) quinolinate synthetase [Ehrlichia chaffeensis]
Length = 314
Score = 199 bits (502), Expect = 2e-50
Identities = 117/314 (37%), Positives = 187/314 (59%), Gaps = 16/314 (5%)
Query: 9 EMDIV---EEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFA 65
E+D++ +EI L +E NAVILAH YQ E+QDIADFIGDSLEL+RKA ADVIVF
Sbjct: 3 ELDVITLLQEIRHLAQESNAVILAHYYQDSEIQDIADFIGDSLELSRKAATTTADVIVFC 62
Query: 66 GVDFMAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAET 125
GV FMAE AKI+NP K VLLP A C++A+ E + + + + + Y+NS AE
Sbjct: 63 GVYFMAEVAKIINPAKKVLLPDLNAGCSLADSCDAESFKKFRELHKDCVSITYINSLAEV 122
Query: 126 KAYADVTVTSANAVKIVSKL-DADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQK 184
KAY+D+ T+++A KI+ ++ + ++F PDK L ++ K T +K+I P G C VH+
Sbjct: 123 KAYSDIICTTSSAEKIIRQIPEEKQILFAPDKFLGAFLEKKTNRKMILWP--GTCIVHES 180
Query: 185 FTIEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNAC--LHDEWVVFTERE 242
F+ ++ + A ++ HPEC + + A I ST ++K + + E++V TE
Sbjct: 181 FSERELIDMMVRHDKAYVLAHPECPGHLLKYAHFIGSTTQLLKFSSDNPNSEFIVLTEEG 240
Query: 243 MVYRLKKLYPEKKFYPARED--------AICIGMKAITLKHIYESLRDMKYKVEVPRDIA 294
+++++KK+ FY + + C M+ TL+ +Y L++ ++ + +I+
Sbjct: 241 IIHQMKKVSSGSTFYIVKTSDSGGCVSCSKCPHMRLNTLEKLYLCLKNGYPEITLEPEIS 300
Query: 295 EKARRAIERMLEMS 308
A+R+++ ML+MS
Sbjct: 301 SMAKRSLDAMLKMS 314
>sp|P24519|NADA_SALTY QUINOLINATE SYNTHETASE A >gi|96809|pir||C37753 quinolinate synthase
A - Salmonella typhimurium
Length = 365
Score = 184 bits (463), Expect = 9e-46
Identities = 115/295 (38%), Positives = 172/295 (57%), Gaps = 23/295 (7%)
Query: 14 EEILKLKEERNAVILAHNYQLPEVQDIADFIG----DSLELARKATKVDADVIVFAGVDF 69
E+I +L +ERNAV++AH Y PE+Q +A+ G DSLE+AR TK A ++ AGV F
Sbjct: 31 EKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGTKHAASTLLVAGVRF 90
Query: 70 MAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYA 129
M ETAKIL+P+KT+L+P+ A C++ ++ +P+ VV+Y N++A KA A
Sbjct: 91 MGETAKILSPEKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARA 150
Query: 130 DVTVTSANAVKIVSKLDA--DVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTI 187
D VTS+ AV+++ LD+ + +I+ PD++L +YV K TG V+ G C VH +F
Sbjct: 151 DWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCW--QGACIVHDEFKT 208
Query: 188 EDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNA--CLHDEWVVFTEREMVY 245
+ + R KK+YP+A L+VHPE + E AD + ST +IK A H + +V T+R + Y
Sbjct: 209 QALTRLKKIYPDAALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFY 268
Query: 246 RLKKLYPEKKFYPA---------REDAICIGMKAITLKHIYESLRD----MKYKV 287
++++ PEK+ A R A C M LK I E L MKY++
Sbjct: 269 KMQQAVPEKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGARMKYRL 323
>sp|P11458|NADA_ECOLI QUINOLINATE SYNTHETASE A >gi|7428533|pir||SYECQA quinolinate
synthetase nadA [validated] - Escherichia coli
>gi|1651334|dbj|BAA35409.1| (D90713) Quinolinate
synthetase A. [Escherichia coli]
>gi|1651337|dbj|BAA35412.1| (D90714) Quinolinate
synthetase A. [Escherichia coli]
>gi|1786964|gb|AAC73837.1| (AE000177) quinolinate
synthetase, A protein [Escherichia coli K12]
Length = 347
Score = 178 bits (447), Expect = 7e-44
Identities = 113/314 (35%), Positives = 178/314 (55%), Gaps = 21/314 (6%)
Query: 14 EEILKLKEERNAVILAHNYQLPEVQDIADFIG----DSLELARKATKVDADVIVFAGVDF 69
E+I +L +ERNAV++AH Y PE+Q +A+ G DSLE+AR K A ++ AGV F
Sbjct: 31 EKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRF 90
Query: 70 MAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYA 129
M ETAKIL+P+KT+L+P+ +A C++ VE +P+ VV+Y N++A KA A
Sbjct: 91 MGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARA 150
Query: 130 DVTVTSANAVKIVSKLDA--DVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTI 187
D VTS+ AV+++ LD+ + +I+ PDK+L YV K TG ++ G C VH +F
Sbjct: 151 DWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCW--QGACIVHDEFKT 208
Query: 188 EDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNA--CLHDEWVVFTEREMVY 245
+ + R ++ YP+A ++VHPE + + AD + ST +I A H +V T+R + Y
Sbjct: 209 QALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFY 268
Query: 246 RLKKLYPEKKFYPA---------REDAICIGMKAITLKHIYESLRD--MKYKVEVPRDIA 294
++++ P+K+ A R A C M L+ I E+L ++V V +
Sbjct: 269 KMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLR 328
Query: 295 EKARRAIERMLEMS 308
E+A + RML+ +
Sbjct: 329 ERALVPLNRMLDFA 342
>pir||E82151 quinolinate synthetase A VC1833 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9656360|gb|AAF94981.1| (AE004259)
quinolinate synthetase A [Vibrio cholerae]
Length = 353
Score = 177 bits (444), Expect = 2e-43
Identities = 108/315 (34%), Positives = 183/315 (57%), Gaps = 21/315 (6%)
Query: 13 VEEILKLKEERNAVILAHNYQLPEVQDIAD----FIGDSLELARKATKVDADVIVFAGVD 68
+ EI +L E++AV++AH Y PE+Q +A+ F+GDSLE+A+ + A ++ AGV
Sbjct: 30 IAEIKQLLIEKDAVLIAHYYTDPEIQALAESTGGFVGDSLEMAKFGNRYPATTLIIAGVR 89
Query: 69 FMAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAY 128
FM E+AKIL P+K +L+P+ A C++ + E +P+ VV+Y N++A KA
Sbjct: 90 FMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKAR 149
Query: 129 ADVTVTSANAVKIVSKLDAD--VVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFT 186
AD VTS+ A++IV LD++ +I+GPD++L Y+AK TG ++ G C VH +F+
Sbjct: 150 ADWVVTSSIALEIVEHLDSEGKPIIWGPDRHLGAYIAKKTGADMLLW--QGECVVHDEFS 207
Query: 187 IEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNA--CLHDEWVVFTEREMV 244
+ + + K LYP+A ++VHPE V E AD + ST +IK A + +V T++ +
Sbjct: 208 ADALRKMKALYPDAAILVHPESPASVVELADAVGSTSQLIKAAKTLPQQKMIVATDKGIF 267
Query: 245 YRLKKLYPEKKFYPA---------REDAICIGMKAITLKHIYESLRD--MKYKVEVPRDI 293
++++++ PEK+ A R A C M L+ I ++LR+ ++++ V +
Sbjct: 268 FKMQQMVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLQAIAQALREGGKQHEIFVDEAL 327
Query: 294 AEKARRAIERMLEMS 308
K+ + RML+ +
Sbjct: 328 RVKSLIPLNRMLDFA 342
>pir||E83519 quinolinate synthetase A PA1004 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946914|gb|AAG04393.1|AE004533_4
(AE004533) quinolinate synthetase A [Pseudomonas
aeruginosa]
Length = 352
Score = 170 bits (427), Expect = 2e-41
Identities = 109/303 (35%), Positives = 172/303 (55%), Gaps = 19/303 (6%)
Query: 23 RNAVILAHNYQLPEVQDIADFIG----DSLELARKATKVDADVIVFAGVDFMAETAKILN 78
+NAV++AH Y P +Q +A+ G DSLE+AR + A +V AGV FM ETAKILN
Sbjct: 41 QNAVLVAHYYCDPVIQALAEETGGCVSDSLEMARFGNQHPAQTVVVAGVRFMGETAKILN 100
Query: 79 PDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTVTSANA 138
P+K VL+P+ ATC++ V+ ++P VV+Y N++A KA AD VTS+ A
Sbjct: 101 PEKRVLMPTLEATCSLDLGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCA 160
Query: 139 VKIVSKL--DADVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERAKKL 196
V+IV L + + +++ PD++L Y+ + TG ++ +G C VH++F + +E K L
Sbjct: 161 VEIVEHLMDNGEPILWAPDQHLGRYIQRETGADMLLW--DGACIVHEEFKAKQLEDMKAL 218
Query: 197 YPNAKLMVHPECIPEVQEKADIIVSTGGMIKNA--CLHDEWVVFTEREMVYRLKKLYPEK 254
YP+A ++VHPE V AD + ST +IK A + ++V T+R + Y++++L P+K
Sbjct: 219 YPDAAILVHPESPESVVALADAVGSTSQLIKAAQTLPNKTFIVATDRGIFYKMQQLCPDK 278
Query: 255 KFYPA---------REDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEKARRAIERML 305
F A R A C M TL+ LR+ ++ V + +A R ++RML
Sbjct: 279 DFIEAPTAGNGAACRSCAHCPWMAMNTLERTLACLREGSGEIFVDPALIPRAVRPLKRML 338
Query: 306 EMS 308
+ +
Sbjct: 339 DFT 341
>pir||B81204 quinolinate synthetase A NMB0394 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225616|gb|AAF40834.1| (AE002395) quinolinate
synthetase A [Neisseria meningitidis MC58]
Length = 370
Score = 166 bits (417), Expect = 2e-40
Identities = 107/312 (34%), Positives = 177/312 (56%), Gaps = 19/312 (6%)
Query: 14 EEILKLKEERNAVILAHNYQLPEVQDIA----DFIGDSLELARKATKVDADVIVFAGVDF 69
+EI L +E+NAV++AH Y P +QD+A +GDSLE+AR + +A +V AGV F
Sbjct: 46 DEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRF 105
Query: 70 MAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYA 129
M E+AKIL P+KTVL+P A C++ E ++P+ VV+Y N++A KA A
Sbjct: 106 MGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARA 165
Query: 130 DVTVTSANAVKIVSKLDA--DVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTI 187
D VTS+ A++IVS L + + +I+GPD++L Y+ + TG ++ G C VH +F
Sbjct: 166 DWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLW--QGSCIVHNEFKG 223
Query: 188 EDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHDE--WVVFTEREMVY 245
+++ K +P A ++VHPE V E D++ ST ++K A E ++V T+ +++
Sbjct: 224 QELAALKAEHPEAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILH 283
Query: 246 RLKKLYPEKKFYPA---------REDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEK 296
++K P+K+F A + A C M +L I +L + ++ + R + E
Sbjct: 284 EMQKQAPDKQFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEA 343
Query: 297 ARRAIERMLEMS 308
A+ ++RML+ +
Sbjct: 344 AKLPLQRMLDFA 355
>pir||C81780 quinolinate synthetase A NMA2090 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380715|emb|CAB85306.1| (AL162758) quinolinate
synthetase A [Neisseria meningitidis Z2491]
Length = 370
Score = 166 bits (416), Expect = 3e-40
Identities = 107/312 (34%), Positives = 178/312 (56%), Gaps = 19/312 (6%)
Query: 14 EEILKLKEERNAVILAHNYQLPEVQDIA----DFIGDSLELARKATKVDADVIVFAGVDF 69
+EI L +E NAV++AH Y P +QD+A +GDSLE+AR + +A +V AGV F
Sbjct: 46 DEIKALLKETNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRF 105
Query: 70 MAETAKILNPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYA 129
M E+AKIL P+KTVL+P A C++ E ++P+ VV+Y N++A KA A
Sbjct: 106 MGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARA 165
Query: 130 DVTVTSANAVKIVSKLDA--DVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTI 187
D VTS+ A++IVS L + + +I+GPD++L Y+ + TG ++ G C VH +F
Sbjct: 166 DWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLW--QGSCIVHNEFKG 223
Query: 188 EDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGMIKNACLHDE--WVVFTEREMVY 245
+++ K +P+A ++VHPE V E +D++ ST ++K A E ++V T+ +++
Sbjct: 224 QELAALKAEHPDAVVLVHPESPQSVIELSDVVGSTSKLLKAAVSRPEKKFIVATDLGILH 283
Query: 246 RLKKLYPEKKFYPA---------REDAICIGMKAITLKHIYESLRDMKYKVEVPRDIAEK 296
++K P+K+F A + A C M +L I +L + ++ + R + E
Sbjct: 284 EMQKQAPDKQFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEA 343
Query: 297 ARRAIERMLEMS 308
A+ ++RML+ +
Sbjct: 344 AKLPLQRMLDFA 355
>gb|AAB50416.1| (U90901) quinolinate synthetase [Ehrlichia muris]
Length = 232
Score = 164 bits (412), Expect = 9e-40
Identities = 90/226 (39%), Positives = 137/226 (59%), Gaps = 5/226 (2%)
Query: 35 PEVQDIADFIGDSLELARKATKVDADVIVFAGVDFMAETAKILNPDKTVLLPSRRATCAM 94
PE+QD+ADFIGDSLEL+RKA ADVIVF GV FMAE AKI+NP K VLLP A C++
Sbjct: 2 PEIQDVADFIGDSLELSRKAATTTADVIVFCGVYFMAEVAKIINPTKRVLLPDLNAGCSL 61
Query: 95 ANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTVTSANAVKIVSKL-DADVVIFG 153
A+ E + + + + + Y+NS AE KAY+D+ TS++A KI+ ++ + ++F
Sbjct: 62 ADSCDAESFKKFRELHKDCVSITYINSLAEVKAYSDIICTSSSAEKIIRQIPEEKQILFA 121
Query: 154 PDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQ 213
PDK L ++ K T +K+I P G C VH+ F+ + + A ++ HPEC +
Sbjct: 122 PDKFLGSFLEKKTNRKMILWP--GTCMVHESFSERKLIDMMVRHSKAYVIAHPECPGHLL 179
Query: 214 EKADIIVSTGGMIK--NACLHDEWVVFTEREMVYRLKKLYPEKKFY 257
A+ I ST ++K + + E++V TE +++++KK+ FY
Sbjct: 180 RHANFIGSTTQLLKFSSERPNSEFIVLTEEGIIHQMKKVSSGSTFY 225
>emb|CAA31216.1| (X12713) nadA gene product (AA 1 - 280) [Escherichia coli]
Length = 280
Score = 156 bits (390), Expect = 3e-37
Identities = 90/242 (37%), Positives = 144/242 (59%), Gaps = 10/242 (4%)
Query: 26 VILAHNYQLPEVQDIADFIG----DSLELARKATKVDADVIVFAGVDFMAETAKILNPDK 81
+++AH Y PE+Q +A+ G DSLE+AR K A ++ AGV FM ETAKIL+P+K
Sbjct: 1 MMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK 60
Query: 82 TVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTVTSANAVKI 141
T+L+P+ +A C++ VE +P+ VV+Y N++A KA AD VTS+ AV++
Sbjct: 61 TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWGVTSSIAVEL 120
Query: 142 VSKLDA--DVVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERAKKLYPN 199
+ LD+ + +I+ PDK+L YV K TG ++ G C VH +F + + R ++ YP+
Sbjct: 121 IDHLDSLCEKIIWAPDKHLGRYVQKQTGGDILCW--QGACIVHDEFKTQALTRLQEEYPD 178
Query: 200 AKLMVHPECIPEVQEKADIIVSTGGMIKNA--CLHDEWVVFTEREMVYRLKKLYPEKKFY 257
A ++VHPE + + AD + ST +I A H +V T+R + Y++++ P+K+
Sbjct: 179 AAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELL 238
Query: 258 PA 259
A
Sbjct: 239 EA 240
>pir||D64689 quinolinate synthetase A - Helicobacter pylori (strain 26695)
>gi|2314524|gb|AAD08398.1| (AE000636) quinolinate
synthetase A (nadA) [Helicobacter pylori 26695]
Length = 336
Score = 152 bits (379), Expect = 7e-36
Identities = 113/341 (33%), Positives = 174/341 (50%), Gaps = 43/341 (12%)
Query: 6 MGVEMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFA 65
M + D+ IL+L + + +++AH YQ E+ ++A + GDSLELA+ A++ D ++IVF
Sbjct: 1 MPTDNDLKAAILELLRDLDVLLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFC 60
Query: 66 GVDFMAETAKILNPDKTVLLPSRRATCAMANML------KVEHIIE---AKRKYPNAPVV 116
GV FM E+ K L DK V++P + + C+MA M+ + H+++ K YP +
Sbjct: 61 GVHFMGESVKALAFDKQVIMP-KLSCCSMARMIDSHYYDRSVHLLKECGVKEFYP----I 115
Query: 117 LYVNSTAETKAYA----DVTVTSANAVKIVSKL--DADVVIFGPDKNLAHYVAKMTG--- 167
Y+NS AE KA V TS NA KI + + F PDK L +A G
Sbjct: 116 TYINSNAEVKAKVAKDDGVVCTSRNASKIFNHALKQNKKIFFLPDKCLGENLALENGLKS 175
Query: 168 -----------KKVIPVPPNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQEKA 216
K V NG C VHQ F +ED+E ++ YP+ + VHPEC P V A
Sbjct: 176 AILGANSQEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNA 235
Query: 217 DIIVSTGGMI---KNACLHDEWVVFTEREMVYRLK-KLYPEKKFYPAREDAICIGMKAIT 272
D ST +I + + + + TE +V RLK K + + F + A+C M T
Sbjct: 236 DFSGSTSQIIEFVEKLSPNQKVAIGTESHLVNRLKAKRHHQNTFILSSTLALCPTMNETT 295
Query: 273 LKHIYESLRDMK-----YKVEVPRDIAEKARRAIERMLEMS 308
LK ++E L+ K +E+ ++A A+ A+ +M+E+S
Sbjct: 296 LKDLFEVLKAYKNHRAYNTIELKDEVARLAKLALTKMMELS 336
>pir||A71828 quinolinate synthetase - Helicobacter pylori (strain J99)
>gi|4155875|gb|AAD06846.1| (AE001550) QUINOLINATE
SYNTHETASE [Helicobacter pylori J99]
Length = 336
Score = 151 bits (377), Expect = 1e-35
Identities = 113/341 (33%), Positives = 173/341 (50%), Gaps = 43/341 (12%)
Query: 6 MGVEMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFA 65
M + D+ I++L + +A+++AH YQ E+ ++A + GDSLELA+ A++ D ++IVF
Sbjct: 1 MPTDNDLKTSIVELLRDLDALLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFC 60
Query: 66 GVDFMAETAKILNPDKTVLLPSRRATCAMANML------KVEHIIE---AKRKYPNAPVV 116
GV FM E+ K L +K V++P + + C+MA M+ + H+++ K YP +
Sbjct: 61 GVHFMGESVKALAFNKQVIMP-KLSCCSMARMIDSHYYDRSVHLLKEYGVKEFYP----I 115
Query: 117 LYVNSTAETKAYA----DVTVTSANAVKIVSKL--DADVVIFGPDKNLAHYVAKMTG--- 167
Y+NS AE KA V TS NA KI + + F PDK L +A G
Sbjct: 116 TYINSNAEVKAKVAKDDGVVCTSRNASKIFNHALKQNKKIFFLPDKCLGENLALENGLKS 175
Query: 168 -----------KKVIPVPPNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQEKA 216
K V NG C VHQ F +ED+E ++ YP+ + VHPEC P V A
Sbjct: 176 AILGINSPEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNA 235
Query: 217 DIIVSTGGMI---KNACLHDEWVVFTEREMVYRLK-KLYPEKKFYPAREDAICIGMKAIT 272
D ST +I + H + + TE +V RLK K + F + A C M T
Sbjct: 236 DFSGSTSQIIEFVEKLSPHQKVAIGTESHLVNRLKAKRNHQNTFILSSTLAFCPTMNETT 295
Query: 273 LKHIYESLRDMK-----YKVEVPRDIAEKARRAIERMLEMS 308
LK ++E L+ K +E+ ++A A+ A+ +M+E+S
Sbjct: 296 LKDLFEVLKAYKNHRAYNAIELKDEVARLAKLALTKMMELS 336
>gb|AAG20079.1| (AE005087) quinolinate synthetase; NadA [Halobacterium sp. NRC-1]
Length = 374
Score = 144 bits (360), Expect = 1e-33
Identities = 103/328 (31%), Positives = 163/328 (49%), Gaps = 44/328 (13%)
Query: 24 NAVILAHNYQLPEVQDIADFIGDSLELARKATKVDADVIVFAGVDFMAETAKILNPD-KT 82
+ V+L HNYQ E+ + ADF+GDS +L+++A DAD ++F GV FMAE+A I+ D ++
Sbjct: 47 DVVVLGHNYQRREIVEHADFVGDSYQLSKEAANADADYVIFGGVTFMAESADIITDDSQS 106
Query: 83 VLLPSRRATCAMANMLKVEHI------IEAKRKYPNAPVVLYVNSTAETKAY----ADVT 132
V+LPS A+C MA M + + I A + Y+NS A+ KA+ +
Sbjct: 107 VILPSMEASCPMAGMAEALQVDAAWADITAAAPDETIIPITYMNSYADLKAFCAEQGGLV 166
Query: 133 VTSANAVKIVSKL--DADVVIFGPDKNLAHYVAKMTGKKVIPVP---------------- 174
TS+NA + D V+F PDK+L A G V
Sbjct: 167 CTSSNAHRAFEWAFERGDKVLFLPDKHLGENTAHRLGMADATVEWDPWAAEGKTAEEVAD 226
Query: 175 -----PNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTGGM---I 226
+G+C VH++FT E V + + +A ++VHPEC EV E AD++ ST + +
Sbjct: 227 ADIVLWDGYCQVHERFTPEHVAEVRADHEDANVVVHPECRREVVEAADVVGSTATITETV 286
Query: 227 KNACLHDEWVVFTEREMVYRLKKLYPEKKFYPAREDAI--CIGMKAITLKHIYESLRDM- 283
+A + W + TE + L++ +PE P DA C M+ I ++ L ++
Sbjct: 287 ADADPGETWAIGTEIHLANHLQRWHPEVNVVPLCGDACMDCNAMRQIDPNYLAWVLEELV 346
Query: 284 ----KYKVEVPRDIAEKARRAIERMLEM 307
+ +EV + AE A+ ++RMLE+
Sbjct: 347 EGRERNVIEVDSEEAELAQVGLDRMLEL 374
>pir||E69663 quinolinate synthetase nadA - Bacillus subtilis
>gi|2635250|emb|CAB14745.1| (Z99118) quinolinate
synthetase [Bacillus subtilis]
Length = 368
Score = 143 bits (357), Expect = 2e-33
Identities = 114/345 (33%), Positives = 171/345 (49%), Gaps = 46/345 (13%)
Query: 9 EMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATK-VDADVIVFAGV 67
+M+ +K K I H+YQ EV AD GDSL+LA+ A K +AD IVF GV
Sbjct: 25 DMETRVAAIKKKFGSRLFIPGHHYQKDEVIQFADQTGDSLQLAQVAEKNKEADYIVFCGV 84
Query: 68 DFMAETAKILNPDK-TVLLPSRRATCAMANMLKVEHIIEAKRKYPNA------PVVLYVN 120
FMAETA +L ++ TV+LP RA C+MA+M ++ A +K + P+ YVN
Sbjct: 85 HFMAETADMLTSEQQTVVLPDMRAGCSMADMADMQQTNRAWKKLQHIFGDTIIPLT-YVN 143
Query: 121 STAETKAYAD----VTVTSANAVKIV--SKLDADVVIFGPDKNLAH-------------- 160
STAE KA+ TVTS+NA K++ + ++F PD++L
Sbjct: 144 STAEIKAFVGKHGGATVTSSNAKKVLEWAFTQKKRILFLPDQHLGRNTAYDLGIALEDMA 203
Query: 161 --------YVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEV 212
VA+ V + GHC VH+KFT +++ ++ P+ +++VHPEC EV
Sbjct: 204 VWDPMKDELVAESGHTNVKVILWKGHCSVHEKFTTKNIHDMRERDPDIQIIVHPECSHEV 263
Query: 213 QEKADIIVSTG---GMIKNACLHDEWVVFTEREMVYRLKKLYPEKKFYPAREDAI-CIGM 268
+D ST I A +W + TE +V R+ +P+K+ D C+ M
Sbjct: 264 VTLSDDNGSTKYIIDTINQAPAGSKWAIGTEMNLVQRIIHEHPDKQIESLNPDMCPCLTM 323
Query: 269 KAITLKHIYESLRDMKY-----KVEVPRDIAEKARRAIERMLEMS 308
I L H+ SL ++ ++VP+ I E A A+ RML ++
Sbjct: 324 NRIDLPHLLWSLEQIEKGEPSGVIKVPKAIQEDALLALNRMLSIT 368
>emb|CAB75321.1| (Y15896) quinolinate synthetase A [Bacillus subtilis]
Length = 363
Score = 143 bits (357), Expect = 2e-33
Identities = 114/345 (33%), Positives = 171/345 (49%), Gaps = 46/345 (13%)
Query: 9 EMDIVEEILKLKEERNAVILAHNYQLPEVQDIADFIGDSLELARKATK-VDADVIVFAGV 67
+M+ +K K I H+YQ EV AD GDSL+LA+ A K +AD IVF GV
Sbjct: 20 DMETRVAAIKKKFGSRLFIPGHHYQKDEVIQFADQTGDSLQLAQVAEKNKEADYIVFCGV 79
Query: 68 DFMAETAKILNPDK-TVLLPSRRATCAMANMLKVEHIIEAKRKYPNA------PVVLYVN 120
FMAETA +L ++ TV+LP RA C+MA+M ++ A +K + P+ YVN
Sbjct: 80 HFMAETADMLTSEQQTVVLPDMRAGCSMADMADMQQTNRAWKKLQHIFGDTIIPLT-YVN 138
Query: 121 STAETKAYAD----VTVTSANAVKIV--SKLDADVVIFGPDKNLAH-------------- 160
STAE KA+ TVTS+NA K++ + ++F PD++L
Sbjct: 139 STAEIKAFVGKHGGATVTSSNAKKVLEWAFTQKKRILFLPDQHLGRNTAYDLGIALEDMA 198
Query: 161 --------YVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEV 212
VA+ V + GHC VH+KFT +++ ++ P+ +++VHPEC EV
Sbjct: 199 VWDPMKDELVAESGHTNVKVILWKGHCSVHEKFTTKNIHDMRERDPDIQIIVHPECSHEV 258
Query: 213 QEKADIIVSTG---GMIKNACLHDEWVVFTEREMVYRLKKLYPEKKFYPAREDAI-CIGM 268
+D ST I A +W + TE +V R+ +P+K+ D C+ M
Sbjct: 259 VTLSDDNGSTKYIIDTINQAPAGSKWAIGTEMNLVQRIIHEHPDKQIESLNPDMCPCLTM 318
Query: 269 KAITLKHIYESLRDMKY-----KVEVPRDIAEKARRAIERMLEMS 308
I L H+ SL ++ ++VP+ I E A A+ RML ++
Sbjct: 319 NRIDLPHLLWSLEQIEKGEPSGVIKVPKAIQEDALLALNRMLSIT 363
>dbj|BAB04939.1| (AP001511) quinolinate synthetase [Bacillus halodurans]
Length = 367
Score = 140 bits (349), Expect = 2e-32
Identities = 113/343 (32%), Positives = 173/343 (49%), Gaps = 46/343 (13%)
Query: 10 MDIVEEILKLKEE--RNAVILAHNYQLPEVQDIADFIGDSLELARKATKV-DADVIVFAG 66
+++ E I + KE + ++L H+YQ EV AD GDSL+LA+ A K +A IVF G
Sbjct: 23 VELEERIRQHKERLGKKLLMLGHHYQRDEVFQFADQTGDSLQLAQIAAKEKEAQFIVFCG 82
Query: 67 VDFMAETAKIL-NPDKTVLLPSRRATCAMANMLKVEHIIEAKRKYP-----NAPVVLYVN 120
V FMAETA +L + ++TVLLP RA C+MA+M + A + + YVN
Sbjct: 83 VHFMAETADLLTSEEQTVLLPDLRAGCSMADMADIHQTERAWERLQLMFGDTILPLTYVN 142
Query: 121 STAETKAYAD----VTVTSANAVKIV--SKLDADVVIFGPDKNLAHYVAKMTG------- 167
STA KA+ TVTS+NA K++ + + ++F PD++L A G
Sbjct: 143 STAAIKAFCGRNGGATVTSSNAKKMLEWAFTQKERLLFLPDQHLGRNTAYELGIPLEAMA 202
Query: 168 ---------------KKVIPVPPNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEV 212
+ + + GHC VH+KFT++ +E +K P+ ++VHPEC +V
Sbjct: 203 VWNPETERLETDQPLENIRVILWKGHCSVHEKFTVKHIEHLRKNEPDMSIIVHPECTHDV 262
Query: 213 QEKADIIVSTGGMIK---NACLHDEWVVFTEREMVYRLKKLYPEKKFYPAREDAI-CIGM 268
AD ST +IK +A +W V TE +V RL +P+K+ C+ M
Sbjct: 263 VIHADDAGSTHYIIKTIESADSGTKWAVGTEMNLVNRLANEHPDKEIVSLNPTMCPCLTM 322
Query: 269 KAITLKHIYESLRDMKYKV-EVPRDIAEKAR----RAIERMLE 306
I ++H+ SL + V + P + +K R A++RML+
Sbjct: 323 NRIDIEHLCWSLDQLAEGVFQHPIKVEDKDRGPALLALQRMLD 365
>gb|AAB50415.1| (U90900) quinolinate synthetase [Ehrlichia canis]
Length = 194
Score = 94.8 bits (232), Expect = 1e-18
Identities = 51/172 (29%), Positives = 97/172 (55%), Gaps = 5/172 (2%)
Query: 89 RATCAMANMLKVEHIIEAKRKYPNAPVVLYVNSTAETKAYADVTVTSANAVKIVSKLDAD 148
+A C++A+ + + + + + + Y+NS+AE KAY+D+ TS++A KI+ ++ D
Sbjct: 6 KAGCSLADSCDAKSFKKFRELHKDCVSITYINSSAEVKAYSDIICTSSSAEKIIRQIPED 65
Query: 149 -VVIFGPDKNLAHYVAKMTGKKVIPVPPNGHCYVHQKFTIEDVERAKKLYPNAKLMVHPE 207
++F PDK L ++ K T +K+I P G C VH+ F+ ++ + A ++ HPE
Sbjct: 66 KQILFAPDKFLGGFLEKKTNRKMILWP--GTCMVHESFSERELIDMMVRHDKAYVLAHPE 123
Query: 208 CIPEVQEKADIIVSTGGMIKNAC--LHDEWVVFTEREMVYRLKKLYPEKKFY 257
C + + I ST ++K + + E+++ TE +++++KKL P FY
Sbjct: 124 CPDNLLRHSHFIGSTTQLLKFSAERPNSEFIILTEEGIIHQMKKLSPGSTFY 175
>emb|CAC12800.1| (AL445343) putative quinolinate synthetase (fragment) [Streptomyces
coelicolor A3(2)]
Length = 279
Score = 83.5 bits (203), Expect = 3e-15
Identities = 77/275 (28%), Positives = 126/275 (45%), Gaps = 47/275 (17%)
Query: 80 DKTVLLPSRRATCAMANMLKVEHIIEAKRKYPNAPV------VLYVNSTAETKAYAD--- 130
D+ V+LP A C+MA+M E + E A + V Y+NS+A+ KA+
Sbjct: 4 DQKVVLPDLAAGCSMADMATAEQVAECWDVLTEAGIAEQVVPVSYMNSSADIKAFTGKHG 63
Query: 131 -VTVTSANAVKIVSKL--DADVVIFGPDKNLAHYVAK----MTGKKVI---PVPPNG--- 177
TS+NA + ++ + V+F PD++L A M+ + + P PNG
Sbjct: 64 GTICTSSNAERALNWAFEQGEKVLFLPDQHLGRNTAVRDLGMSLEDCVVYNPHRPNGGLT 123
Query: 178 --------------HCYVHQKFTIEDVERAKKLYPNAKLMVHPECIPEVQEKADIIVSTG 223
HC VH +F+++ V ++ P ++VHPEC EV AD + ST
Sbjct: 124 AKELRDANMILWRGHCSVHGRFSLDSVNDVRERIPGVNVLVHPECKHEVVAAADYVGSTE 183
Query: 224 GMIK---NACLHDEWVVFTEREMVYRLKKLY---PEKKFYPAREDAICIGMKAITLKHI- 276
+IK A +W + TE +V RL + ++ + + C M I L H+
Sbjct: 184 YIIKALEAAPAGSKWAIGTELNLVRRLANRFAAEDKEIVFLDKTVCFCSTMNRIDLPHLV 243
Query: 277 --YESLRD--MKYKVEVPRDIAEKARRAIERMLEM 307
ESL + + ++EV ++ A+ A+ERML +
Sbjct: 244 WTLESLAEGTLVNRIEVDQETEAFAKLALERMLAL 278
>dbj|BAB09392.1| (AB024031) gb|AAF26953.1~gene_id:K6A12.7~similar to unknown protein
[Arabidopsis thaliana]
Length = 718
Score = 72.6 bits (175), Expect = 5e-12
Identities = 67/250 (26%), Positives = 107/250 (42%), Gaps = 55/250 (22%)
Query: 13 VEEILKLKEERNAVILAHNYQLPEVQDIADF---------IGDSLELARKAT---KVDAD 60
VEE++ + +E+ ++AH Y PEVQ + I DSL +A A K
Sbjct: 263 VEELVNVLKEKKIGVVAHFYMDPEVQGVLTAAQKHWPHISISDSLVMADSAVTMAKAGCQ 322
Query: 61 VIVFAGVDFMAETAKILNPDK------TVLLPSRRATCAMANMLKVE---HIIEAKRKYP 111
I GVDFM+E + + + C++A+ + +EA + P
Sbjct: 323 FITVLGVDFMSENVRAILDQAGFEKVGVYRMSDETIGCSLADAASAPAYLNYLEAASRSP 382
Query: 112 NAPVVLYVNSTAETKAYAD-----VTVTSANAVKIVSKLDADV----VIFGPDKNLAHYV 162
+ V+Y+N++ ETKA+A +T TS+N V+ + + A + V +GPD + +
Sbjct: 383 PSLHVVYINTSLETKAFAHELVPTITCTSSNVVQTILQAFAQMPELTVWYGPDSYMGANI 442
Query: 163 AK-------MTGKKVIPVPPN------------------GHCYVHQKFTIEDVERAKKLY 197
K MT +++ + P G C VH F E VER K +Y
Sbjct: 443 VKLFQQMTLMTNEEIANIHPKHSLDSIKSLLPRLHYFQEGTCIVHHLFGHEVVERIKYMY 502
Query: 198 PNAKLMVHPE 207
+A L H E
Sbjct: 503 CDAFLTAHLE 512
>pir||T35544 probable quinolinate synthetase - Streptomyces coelicolor
(fragment) >gi|4539231|emb|CAB39889.1| (AL049497)
putative quinolinate synthetase [Streptomyces coelicolor
A3(2)]
Length = 154
Score = 69.1 bits (166), Expect = 6e-11
Identities = 43/99 (43%), Positives = 58/99 (58%), Gaps = 4/99 (4%)
Query: 11 DIVEEILKLKEERN--AVILAHNYQLPEVQDIADFIGDSLELAR-KATKVDADVIVFAGV 67
D+V KE+ +L H+YQ EV AD GDS +LAR A + +A+ IVF GV
Sbjct: 46 DLVARARAAKEKLGDKVFVLGHHYQRDEVIQFADVTGDSFKLARDAAARPEAEYIVFCGV 105
Query: 68 DFMAETAKIL-NPDKTVLLPSRRATCAMANMLKVEHIIE 105
FMAE+A IL + D+ V+LP A C+MA+M E + E
Sbjct: 106 HFMAESADILTSNDQKVVLPDLAAGCSMADMATAEQVAE 144
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.135 0.380
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105999428
Number of Sequences: 2977
Number of extensions: 4250033
Number of successful extensions: 11587
Number of sequences better than 1.0e-10: 33
Number of HSP's better than 0.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 11404
Number of HSP's gapped (non-prelim): 35
length of query: 308
length of database: 189,106,746
effective HSP length: 58
effective length of query: 250
effective length of database: 154,394,500
effective search space: 38598625000
effective search space used: 38598625000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)