BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2354 (putP-3) DE:PROLINE SYMPORTER (PROLINE PERMEASE).
(492 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75188 proline symporter (proline permease). PAB2354 - Pyro... 961 0.0
dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodur... 443 e-123
pir||C71008 probable proline permease - Pyrococcus horikoshii >g... 365 e-100
pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyss... 360 2e-98
sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/P... 332 6e-90
pir||T44298 proline transporter [imported] - Bacillus halodurans... 327 2e-88
gb|AAA24465.1| (L01152) proline permease [Escherichia coli] 313 3e-84
pir||B81297 sodium/proline symporter Cj1502c [imported] - Campyl... 312 4e-84
gb|AAA24463.1| (L01150) proline permease [Escherichia coli] >gi|... 312 4e-84
pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens >... 312 4e-84
sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 312 4e-84
gb|AAA24462.1| (L01133) proline permease [Escherichia coli] 312 6e-84
gb|AAA24461.1| (L01132) proline permease [Escherichia coli] >gi|... 312 6e-84
gb|AAA24466.1| (L01153) proline permease [Escherichia coli] >gi|... 311 1e-83
pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio... 311 1e-83
gb|AAA24468.1| (L01155) proline permease [Escherichia coli] 311 1e-83
pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Ps... 308 1e-82
gb|AAA99282.1| (L01140) proline permease [Salmonella sp.] >gi|15... 308 1e-82
gb|AAA99288.1| (L01146) proline permease [Salmonella sp.] >gi|15... 308 1e-82
gb|AAA99291.1| (L01149) proline permease [Salmonella sp.] 307 1e-82
gb|AAA99290.1| (L01148) proline permease [Salmonella sp.] 307 1e-82
sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 307 2e-82
gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi] 307 2e-82
gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium] 307 2e-82
gb|AAA99279.1| (L01137) proline permease [Salmonella sp.] 307 3e-82
gb|AAA99281.1| (L01139) proline permease [Salmonella sp.] 307 3e-82
gb|AAA99278.1| (L01136) proline permease [Salmonella sp.] 307 3e-82
emb|CAA70363.1| (Y09163) proline transport system [Corynebacteri... 306 3e-82
pir||S10220 sodium/proline symporter - Salmonella typhimurium 306 3e-82
gb|AAA99286.1| (L01144) proline permease [Salmonella sp.] >gi|15... 306 3e-82
gb|AAA99280.1| (L01138) proline permease [Salmonella sp.] 305 6e-82
gb|AAA99284.1| (L01142) proline permease [Salmonella sp.] >gi|15... 305 6e-82
pir||A71980 sodium/proline symporter - Helicobacter pylori (stra... 304 1e-81
pir||G64526 sodium/proline symporter - Helicobacter pylori (stra... 303 2e-81
gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus... 300 2e-80
pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis >g... 298 1e-79
pir||T48676 proline uptake protein [validated] - Staphylococcus ... 298 1e-79
gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomona... 296 4e-79
sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 280 2e-74
pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisse... 276 5e-73
gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium ... 260 3e-68
pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococc... 248 1e-64
pir||D65118 pantothenate permease [validated] - Escherichia coli... 221 1e-56
sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE... 221 1e-56
sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE... 219 6e-56
pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|... 189 6e-47
pir||C69115 sodium/proline symporter (proline permease) - Methan... 176 5e-43
gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgid... 165 1e-39
gb|AAF45263.1| (AF230602) proline permease [Escherichia coli] >g... 160 3e-38
gb|AAF45280.1| (AF230619) proline permease [Escherichia coli] 160 3e-38
gb|AAF45283.1| (AF230622) proline permease [Escherichia coli] 160 3e-38
gb|AAF45285.1| (AF230624) proline permease [Escherichia coli] 160 3e-38
gb|AAF45264.1| (AF230603) proline permease [Escherichia coli] >g... 158 1e-37
gb|AAF45286.1| (AF230625) proline permease [Escherichia coli] 157 3e-37
pir||E70201 pantothenate permease (panF) homolog - Lyme disease ... 157 3e-37
gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus] >... 154 2e-36
sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK IN... 146 7e-34
gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus] >... 141 2e-32
sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS IN... 141 2e-32
emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas... 140 3e-32
pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii ... 139 5e-32
pir||F83241 probable sodium:solute symporter PA3234 [imported] -... 139 9e-32
pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xy... 133 4e-30
pir||E70480 probable sodium/proline symporter ssf [similarity] -... 131 2e-29
pir||T03475 transmembrane protein - Rhodobacter capsulatus >gi|3... 130 3e-29
sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE... 128 1e-28
pir||S52839 dhlC protein - Xanthobacter autotrophicus >gi|763398... 128 2e-28
dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemo... 127 2e-28
gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus] >... 125 8e-28
sp|P11170|SL51_RABIT SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCO... 121 2e-26
gb|AAF17249.1|AF208031_1 (AF208031) SGLT1 protein [Mus musculus] 119 8e-26
dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Ba... 118 1e-25
pir||G83610 probable sodium:solute symporter PA0287 [imported] -... 117 2e-25
pir||E83468 probable sodium:solute symport protein PA1418 [impor... 117 2e-25
emb|CAB59438.1| (AL132644) putative transmembrane transport prot... 117 3e-25
gi|6981552 solute carrier family 5, member alpha 1 (Na+/glucose ... 115 9e-25
dbj|BAA19172.1| (AB000729) Na/glucose cotransporter [Rattus norv... 115 9e-25
emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Str... 115 9e-25
gi|11528510 solute carrier family 5 (choline transporter), membe... 115 2e-24
gb|AAG36945.1| (AF276872) sodium and chloride-dependent high-aff... 115 2e-24
gi|8394316 solute carrier family 5, member alpha 3 [Mus musculus... 114 3e-24
gi|4507031 solute carrier family 5 (sodium/glucose cotransporter... 113 4e-24
dbj|BAA90484.1| (AB030947) high-affinity choline transporter CHT... 113 4e-24
gi|9790215 sodium-glucose cotransporter 1 [Mus musculus] >gi|668... 113 6e-24
gi|11526219 solute carrier family 5 (inositol transporters), mem... 113 6e-24
pir||H75513 probable sodium/proline symporter DR0477 [similarity... 112 8e-24
sp|P53793|SL53_BOVIN SODIUM/MYO-INOSITOL COTRANSPORTER (NA(+)/MY... 112 1e-23
gi|5902092 solute carrier family 5 (inositol transporters), memb... 112 1e-23
gi|11141885 solute carrier family 5 (choline transporter), membe... 112 1e-23
pir||T35201 probable transmembrane transport - Streptomyces coel... 111 1e-23
gb|AAB68775.1| (U95125) Na+/myo-inositol cotransporter [Bos taurus] 111 2e-23
sp|P31637|SL53_CANFA SODIUM/MYO-INOSITOL COTRANSPORTER (NA(+)/MY... 110 4e-23
sp|P53791|SL51_SHEEP SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCO... 109 7e-23
gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgid... 109 7e-23
pir||S48858 glucose transport protein homolog - sheep 108 1e-22
dbj|BAA22950.1| (AB008225) Na+-glucose cotransporter type 1 (SGL... 108 2e-22
gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgid... 108 2e-22
pir||S48857 glucose transport protein - sheep >gi|2148056|pir||S... 107 4e-22
gb|AAF54633.1| (AE003691) CG6723 gene product [Drosophila melano... 107 4e-22
sp|P31636|SL54_PIG SODIUM/GLUCOSE COTRANSPORTER 3 (NA(+)/GLUCOSE... 103 4e-21
gi|4507035 solute carrier family 5 (sodium iodide symporter), me... 102 1e-20
pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC... 101 2e-20
emb|CAC00574.1| (AL109659) dJ1024N4.1 (novel Sodium:solute sympo... 101 2e-20
emb|CAB51758.1| (AL008723) dJ90G24.4 (SAAT1 (low affinity sodium... 101 2e-20
dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens] 101 2e-20
dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacil... 101 2e-20
gb|AAG01742.1|AF251268_1 (AF251268) low affinity sodium-glucose ... 101 3e-20
gb|AAG01741.1|AF251267_1 (AF251267) low affinity sodium-glucose ... 100 4e-20
pir||G71705 alkaline phosphatase synthesis sensor protein phor (... 100 4e-20
emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa] 100 5e-20
emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa] 100 5e-20
gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transpo... 98 2e-19
pir||B69833 metabolite permease homolog yhjB - Bacillus subtilis... 97 4e-19
gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacte... 96 1e-18
pir||A82432 sodium/solute symporter VCA0667 [imported] - Vibrio ... 95 2e-18
pir||S68513 thyroid iodide transport protein - rat >gi|1399954|g... 94 3e-18
emb|CAA04650.1| (AJ001290) sodium myo-inositol transporter [Ratt... 94 3e-18
pir||A71662 sodium/pantothenate symporter (panF) RP571 - Rickett... 94 5e-18
prf||2204393A Na/I symporter [Rattus norvegicus] 93 8e-18
pir||C69903 proline permease homolog yodF - Bacillus subtilis >g... 92 1e-17
gb|AAF57489.1| (AE003792) CG10444 gene product [Drosophila melan... 92 2e-17
gb|AAB81169.1| (AF006665) YolC [Bacillus subtilis] 91 3e-17
gb|AAK42614.1| Metabolite permease, putative [Sulfolobus solfata... 89 9e-17
pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (str... 89 9e-17
gb|AAD37480.1|AF080067_1 (AF080067) sodium-dependent multi-vitam... 89 2e-16
sp|P31448|YIDK_ECOLI HYPOTHETICAL 62.1 KD PROTEIN IN EMRD-GLVG I... 89 2e-16
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr... 88 2e-16
gi|11429441 solute carrier family 5 (sodium-dependent vitamin tr... 88 2e-16
sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 84 4e-15
gb|AAF52616.1| (AE003620) CG8451 gene product [Drosophila melano... 83 7e-15
emb|CAC16517.1| (AL450223) putative integral membrane transport ... 83 9e-15
emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Str... 82 1e-14
emb|CAC11445.1| (AL445063) conserved hypothetical membrane prote... 79 1e-13
gb|AAF57193.1| (AE003779) CG2191 gene product [Drosophila melano... 77 5e-13
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter... 76 7e-13
prf||1909123A Na glucose cotransporter [Homo sapiens] 76 7e-13
sp|P53792|SL52_RAT SODIUM/GLUCOSE COTRANSPORTER 2 (NA(+)/GLUCOSE... 76 7e-13
sp|P26430|SL52_RABIT SODIUM/NUCLEOSIDE COTRANSPORTER (NA(+)/NUCL... 76 9e-13
emb|CAB94614.1| (AL359214) putative permease [Streptomyces coeli... 75 3e-12
gb|AAF55596.1| (AE003723) CG7720 gene product [alt 1] [Drosophil... 71 2e-11
>pir||D75188 proline symporter (proline permease). PAB2354 - Pyrococcus abyssi
(strain Orsay) >gi|5457464|emb|CAB48955.1| (AJ248283)
PROLINE SYMPORTER (PROLINE PERMEASE). [Pyrococcus
abyssi]
Length = 492
Score = 961 bits (2458), Expect = 0.0
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 1 MSNAYEMLKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSS 60
MSNAYEMLKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSS
Sbjct: 1 MSNAYEMLKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSS 60
Query: 61 GRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFE 120
GRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFE
Sbjct: 61 GRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFE 120
Query: 121 ARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYM 180
ARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYM
Sbjct: 121 ARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYM 180
Query: 181 ILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAG 240
ILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAG
Sbjct: 181 ILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAG 240
Query: 241 VVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV 300
VVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV
Sbjct: 241 VVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV 300
Query: 301 PDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQ 360
PDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQ
Sbjct: 301 PDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQ 360
Query: 361 EVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLI 420
EVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLI
Sbjct: 361 EVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLI 420
Query: 421 LSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKP 480
LSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKP
Sbjct: 421 LSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKP 480
Query: 481 PENVEELMKAME 492
PENVEELMKAME
Sbjct: 481 PENVEELMKAME 492
>dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodurans]
Length = 507
Score = 443 bits (1126), Expect = e-123
Identities = 214/498 (42%), Positives = 331/498 (65%), Gaps = 17/498 (3%)
Query: 11 PVALVAFLFTLILPILVGFYAMKRTK-SEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
P+A+ + L+ +L+G + K++ DFF+ GR ++K TVALSAVSSGRS+WLVLG
Sbjct: 6 PLAVAILIAYLVALLLIGLLSSKKSSVGMTDFFIAGRNLNKWTVALSAVSSGRSAWLVLG 65
Query: 70 LSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKI 129
++G AY G+ AVWA GYI E+F F Y+ R R +SE+ +IT+PD E RF D + I
Sbjct: 66 VTGTAYATGLDAVWAVAGYITVEVFLFFYVARRFRAYSEQTGSITIPDILETRFNDKTHI 125
Query: 130 LRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVA 189
LR ++ II+ F+ +YV +Q AG +T++G+S T + ++ ++++ Y +LGGF AV+
Sbjct: 126 LRGGSAFIIMFFMIAYVASQLVAGGGAFATSMGVSSSTGMWVTAVILLAYTMLGGFHAVS 185
Query: 190 YNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIGFLGIG 249
DV++A M + LV+LPV+A+ +GG + +L+V+H +P+AFG G VIG LGIG
Sbjct: 186 KTDVVQAGFMFVSLVILPVVAIIGLGGFDPLLQVMHTEGGGFTSPFAFGFGAVIGLLGIG 245
Query: 250 FGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGK 309
FGSPG PHI+VRYMS+ + ++R + ++ + WNV++ WGA+ +GLAGRA PDVS LP
Sbjct: 246 FGSPGNPHILVRYMSLKNVKEMRQAALISSVWNVLMGWGAVMIGLAGRAYFPDVSLLPNG 305
Query: 310 NAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKI 369
+ E ++ L ++ P+ +G L+ + AAI+S+ADSQLLV +S V+D+YQ++ ++ K+
Sbjct: 306 DQEQVFLMLGSEILHPLFFGFLLVAVLAAIMSSADSQLLVGSSAFVRDIYQKMFRRNRKL 365
Query: 370 DEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTT 429
+K + +SR+T +V L+ ILA+ A++ +FW VLFA+GGLGA FGP L+LS YWKG T
Sbjct: 366 SQKKLVRLSRLTTVVFMGLSLILAFTAQEFVFWMVLFAFGGLGACFGPALLLSFYWKGVT 425
Query: 430 KWGVLAGMIVGTITTIVWK-------LYLKPITGL---------YELVPAFIFSLIATII 473
+ GVL GMI G +T I+ K +L + L YE VP FI + T++
Sbjct: 426 RQGVLWGMIAGLLTVILVKQQPQWTYAFLPDVKELLNTYFFGITYEAVPGFIVATTITVV 485
Query: 474 VSMITKPPENVEELMKAM 491
+S+ TK P++ +++++ +
Sbjct: 486 ISLFTKRPKHAKQIIERL 503
>pir||C71008 probable proline permease - Pyrococcus horikoshii
>gi|3257784|dbj|BAA30467.1| (AP000006) 537aa long
hypothetical proline permease [Pyrococcus horikoshii]
Length = 537
Score = 365 bits (927), Expect = e-100
Identities = 186/501 (37%), Positives = 305/501 (60%), Gaps = 26/501 (5%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
L+ FL L+L +G++A + TK+EE +F+GGR + + LS +S S WL+LG G
Sbjct: 6 LLGFLIYLVLLAYIGWWANRYTKTEEQYFIGGRKVHVLAATLSDKASDFSGWLMLGYPGT 65
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133
A+K G+ A WAA+G + + ++ +G RLR ++ +F +IT+PDY EAR +D +K++RI
Sbjct: 66 AFKTGLGAFWAAIGCLFGTLADYLLIGPRLRIYAGKFRSITLPDYLEARLKDNTKLIRIL 125
Query: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193
++ II+IF+T+YV AQF AG KT S A G+S+ T ++I+V+++ Y+I GGF AV + DV
Sbjct: 126 SAAIILIFMTAYVAAQFAAGGKTFSEAFGVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
Query: 194 IRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIGFLGIGF--- 250
++A+ M++ L+++P++A+A++GG ++ +++ +++P ++P+ G+ IG+
Sbjct: 186 VQAMFMLLTLIIMPILALAEIGGLDKATQIIGSVNPAKLHPFGGATGLAAIVFAIGYASW 245
Query: 251 --GSPGQPHIIVRYMSIDDPNKLRVSTV-VGTFWNVVLAWGAIFVGLAGRAIVPDVSQLP 307
G GQPHI+ RYMS++DP KLR + + W ++ WGA F G G A+ + S +
Sbjct: 246 IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALAINGS-IK 304
Query: 308 GKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGT 367
+ E I P ++ + P + G +I GI +A++STADSQLLV +S + +D+Y +V+ G
Sbjct: 305 IDDPEKIVPAMAVHFLPSWIAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL--GQ 362
Query: 368 KIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKG 427
++ +K + ISRV V +V +A A +I+ V AWGGL FGP L LSL+WK
Sbjct: 363 ELGKKQMVNISRVVVAIVSLIAMWFAISGPKVIYQMVATAWGGLAVGFGPILTLSLWWKR 422
Query: 428 TTKWGVLAGMIVGTITTIVWKLYL-----------------KPITGLYELVPAFIFSLIA 470
TK + GM G I+ ++ + + K G+ F +L+
Sbjct: 423 VTKEAGIIGMGYGLISEVLLEAKIYGWAFNPNAPGFFGTLGKWFNGVPVFFINFFITLLV 482
Query: 471 TIIVSMITKPPENVEELMKAM 491
IIVS++TKPPE+V +L K +
Sbjct: 483 IIIVSLLTKPPEDVVKLHKEL 503
>pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyssi (strain
Orsay) >gi|5458209|emb|CAB49698.1| (AJ248285) proline
permease (putP-2) [Pyrococcus abyssi]
Length = 537
Score = 360 bits (914), Expect = 2e-98
Identities = 186/503 (36%), Positives = 299/503 (58%), Gaps = 30/503 (5%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
L FL L++ +G++A K TK+E+ +FVGGR + + LS +S S WL+LG G
Sbjct: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133
A+K G+ A WA +G + + ++ +G RLR ++ +F AIT+PDY EAR +D +K++RI
Sbjct: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
Query: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193
++ II++F+T+YV AQF AG KT + A +S+ T ++I+V+++ Y+I GGF AV + DV
Sbjct: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
Query: 194 IRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIGFLGIGF--- 250
++A+ M++ L+++P++A+ ++GG + +++ ++DP ++P+ G IG+
Sbjct: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASW 245
Query: 251 --GSPGQPHIIVRYMSIDDPNKLRVSTV-VGTFWNVVLAWGAIFVGLAGRAIVPDVSQLP 307
G GQPHI+ RYMS++DP KLR + + W ++ WGA F G G A+V S +
Sbjct: 246 IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGS-IK 304
Query: 308 GKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGT 367
++ E I P ++ + P + G +I GI +A++STADSQLLV +S + +D+Y +V+ G
Sbjct: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL--GQ 362
Query: 368 KIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKG 427
++ +K + ISR+ V V +A A +I+ V AWGGL FGP L LSL+WK
Sbjct: 363 ELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKR 422
Query: 428 TTKWGVLAGMIVGTITTIV-------WKL------YLKPITGLYELVPAFIFSLIAT--- 471
TK + GM G I+ ++ W + + + VP F + T
Sbjct: 423 VTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFI 482
Query: 472 -IIVSMITKPPENV----EELMK 489
IIVS++TKPPE+V EEL K
Sbjct: 483 IIIVSLLTKPPEDVVKLHEELFK 505
>sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/PROLINE SYMPORTER)
>gi|7442757|pir||H69670 sodium/proline symporter opuE -
Bacillus subtilis >gi|2114423|gb|AAB66512.1| (U92466)
osmoregulated proline transporter [Bacillus subtilis]
>gi|2465556|gb|AAB72182.1| (AF011545) OpuE [Bacillus
subtilis] >gi|2632980|emb|CAB12486.1| (Z99107) proline
transporter [Bacillus subtilis]
Length = 492
Score = 332 bits (842), Expect = 6e-90
Identities = 172/464 (37%), Positives = 276/464 (59%), Gaps = 8/464 (1%)
Query: 22 ILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTA 81
I +L+G+YA K+T D+ +GGR + ALSA ++ S W+++G+ G + G++
Sbjct: 14 IAMLLIGWYAFKKTTDINDYMLGGRGLGPFVTALSAGAADMSGWMLMGVPGAMFATGLST 73
Query: 82 VWAAVGYIVAEMFQFVYMGIRLRKFSERFN-AITVPDYFEARFRDTSKILRIAASIIIII 140
+W A+G + ++ + RLR ++E + AIT+PD+F+ RF+ +S +L+I +++II+I
Sbjct: 74 LWLALGLTIGAYSNYLLLAPRLRAYTEAADDAITIPDFFDKRFQHSSSLLKIVSALIIMI 133
Query: 141 FLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMI 200
F T Y + +G + +A G L ++ ++++Y + GGF+AV+ D ++ IM
Sbjct: 134 FFTLYTSSGMVSGGRLFESAFGADYKLGLFLTTAVVVLYTLFGGFLAVSLTDFVQGAIMF 193
Query: 201 IGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGV--VIGFLGIGFGSPGQPHI 258
LV++P++A VGG + A++P L++ + GA V +I +L G G GQPHI
Sbjct: 194 AALVLVPIVAFTHVGGVAPTFHEIDAVNPHLLDIFK-GASVISIISYLAWGLGYYGQPHI 252
Query: 259 IVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGKNAEMIYPYL 318
IVR+M+I D L+ + +G W ++ G++ GL G A + K+ EMI+
Sbjct: 253 IVRFMAIKDIKDLKPARRIGMSWMIITVLGSVLTGLIGVAYAHKFG-VAVKDPEMIFIIF 311
Query: 319 SAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTIS 378
S F P++ G L+ I AAI+S+ SQLLV AS V +DLY+ ++ K +K + I
Sbjct: 312 SKILFHPLITGFLLSAILAAIMSSISSQLLVTASAVTEDLYRSFFRR--KASDKELVMIG 369
Query: 379 RVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMI 438
R++VLV+ +A +L+ I V +AW G G++FGP ++LSLYWK +WG LA MI
Sbjct: 370 RLSVLVIAVIAVLLSLNPNSTILDLVGYAWAGFGSAFGPAILLSLYWKRMNEWGALAAMI 429
Query: 439 VGTITTIVW-KLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
VG T ++W L TG+YE++P FI S+IA IIVSMITK P
Sbjct: 430 VGAATVLIWITTGLAKSTGVYEIIPGFILSMIAGIIVSMITKRP 473
>pir||T44298 proline transporter [imported] - Bacillus halodurans
>gi|4512352|dbj|BAA75317.1| (AB011836) proline
transporter [Bacillus halodurans]
>gi|10173274|dbj|BAB04379.1| (AP001509) sodium/proline
symporter [Bacillus halodurans]
Length = 501
Score = 327 bits (830), Expect = 2e-88
Identities = 174/490 (35%), Positives = 282/490 (57%), Gaps = 21/490 (4%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
L+ F+ L+ +++G A + T + D+ +GGR + ALSA +S SSWL+LGL G
Sbjct: 6 LITFIVYLVGMLVIGLIAYRMTNNLSDYVLGGRRLGGSVAALSAGASDMSSWLLLGLPGA 65
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
Y G+ +W AVG + + ++ RLR ++E ++IT+PD+ E RF D SKILRI
Sbjct: 66 LYVGGMGEIWIAVGLAIGAYLNWQFLAARLRNYTEIAKDSITLPDFLENRFHDKSKILRI 125
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y A GA + G++ AL I ++II Y LGGF+AV++ D
Sbjct: 126 VSALVILVFFTFYTSAGLVGGALLFEASFGMTYIQALWIGAIVIISYTFLGGFLAVSWTD 185
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIG---FLGIG 249
+ ++M + L+++P++A+ K+GG E L + A+D ++ AF VIG L G
Sbjct: 186 FFQGILMFLALIIVPIVAINKMGGFSETLNAVGAIDTAYLD--AFQGATVIGVASLLAWG 243
Query: 250 FGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVS---QL 306
G GQPHI+ R+M++ ++ + +G W V+ +GAIF G G A ++
Sbjct: 244 LGYFGQPHIVTRFMAVKSLKEIPKARFIGMTWMVLALFGAIFTGFVGIAYFSATGPGPEI 303
Query: 307 PGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKG 366
G+ E ++ + F P + G L+ I +AI+ST DSQLLV +S + +D Y+ +++K
Sbjct: 304 AGEARETVFILFTQILFDPWVAGFLLAAILSAIMSTIDSQLLVSSSALAEDFYKGMLRKN 363
Query: 367 TKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWK 426
+K + + R V+++ +A +LAY + V +AW G GA+FGP L+LSL+WK
Sbjct: 364 A--SQKELVWVGRFGVVLIALVAIVLAYNPDSTVLDLVGYAWAGFGAAFGPVLLLSLFWK 421
Query: 427 GTTKWGVLAGMIVGTITTIVW---------KLYLKPITGLYELVPAFIFSLIATIIVSMI 477
T+ G LAGM+VG T I+W + PI GLYE++P FI + IA I+VS +
Sbjct: 422 RMTRNGALAGMVVGGATVIIWAELTNWFNLSVEQYPILGLYEIIPGFILASIAIIVVSRL 481
Query: 478 -TKPPENVEE 486
+PP+ +++
Sbjct: 482 DQEPPQEIQD 491
>gb|AAA24465.1| (L01152) proline permease [Escherichia coli]
Length = 489
Score = 313 bits (793), Expect = 3e-84
Identities = 171/473 (36%), Positives = 270/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S+ILRI
Sbjct: 68 VFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL V I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGVAATILYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PVI + VGG + L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV---PDVSQLPG 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A P V+
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNEHPAVAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+NAE ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRK--H 365
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
+K + + RV VLVV +A LA ++ + V +AW G GA+FGP ++ S+ W
Sbjct: 366 ASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK + GLYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGALTVIVWKQF--GWLGLYEIIPGFIFGSIGIVVFSLLGKAP 476
>pir||B81297 sodium/proline symporter Cj1502c [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6968927|emb|CAB73923.1|
(AL139078) sodium/proline symporter [Campylobacter
jejuni]
Length = 495
Score = 312 bits (792), Expect = 4e-84
Identities = 164/474 (34%), Positives = 275/474 (57%), Gaps = 10/474 (2%)
Query: 8 LKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLV 67
+ P+A++ ++ L++ + +GFY K+ K+ ED+F+GGR M + ALSA +S S WL+
Sbjct: 12 INTPIAVMFVVYALLM-LYIGFYFYKQNKNSEDYFLGGRTMGPVISALSAGASDMSGWLL 70
Query: 68 LGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRDT 126
+GL G Y G + A+G + ++++ RLR ++ N++T+PDYFE RF D
Sbjct: 71 MGLPGALYVSGFIDSYIAIGLTIGASLNWIFVAKRLRIYTSVIANSLTIPDYFETRFDDD 130
Query: 127 SKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFI 186
ILRI +++I+IF T YV + +GAK + GI AL ++I+ Y LGG+
Sbjct: 131 KHILRIVCAVVILIFFTFYVSSGLVSGAKLFESTFGIRYDYALTTGTIIIVAYTFLGGYK 190
Query: 187 AVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVV--IG 244
AV + D+I+ ++M++ L+++P++ + +GG E + ++ + P+ ++ G G+V I
Sbjct: 191 AVCWTDMIQGLLMMMALIIVPLVMLYHLGGFGEAMNIVREIKPQALS-MGEGVGIVSIIS 249
Query: 245 FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVS 304
L G G GQPHI+VR+MSI + ++T +G W V A +G+ G A V
Sbjct: 250 ALAWGLGYFGQPHILVRFMSIRSTKDIPMATFIGIAWMAVCLLSACMIGILGIAYVHKF- 308
Query: 305 QLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIK 364
+L ++ E I+ +S F P + GIL+ I AAI+STA SQLLV +ST+ +D Y+++ +
Sbjct: 309 ELSLQDPEKIFIVMSQLLFNPWIAGILLSAILAAIMSTASSQLLVSSSTIAEDFYKKIFR 368
Query: 365 KGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLY 424
+ L + ++ VL+V +A +++ + V +AW G GASFG ++ SL+
Sbjct: 369 EDA--PSHIVLNLGKLGVLLVAVIAFLISTDKNSSVLSIVSYAWAGFGASFGSVMLFSLF 426
Query: 425 WKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMIT 478
W T+ G + GMI G T ++WK + +GLYE+VP F+ + + II S+ T
Sbjct: 427 WSRMTRVGAILGMITGAATVVLWKNFAN--SGLYEIVPGFLVASVVIIIASLFT 478
>gb|AAA24463.1| (L01150) proline permease [Escherichia coli]
>gi|147441|gb|AAA24464.1| (L01151) proline permease
[Escherichia coli]
Length = 489
Score = 312 bits (792), Expect = 4e-84
Identities = 171/473 (36%), Positives = 269/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S+ILRI
Sbjct: 68 VFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PVI + VGG + L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A D L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNDHPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+NAE ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRK--H 365
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
+K + + RV VLVV +A LA ++ + V +AW G GA+FGP ++ S+ W
Sbjct: 366 ASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK + GLYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGALTVIVWKQF--GWLGLYEIIPGFIFGSIGIVVFSLLGKAP 476
>pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens
>gi|509694|dbj|BAA06838.1| (D32069) proline permease
[Pseudomonas fluorescens] >gi|913690|gb|AAC60490.1|
(S76070) proline permease [Pseudomonas fluorescens,
Peptide, 494 aa] >gi|1092517|prf||2024229A Pro permease
[Pseudomonas fluorescens]
Length = 494
Score = 312 bits (792), Expect = 4e-84
Identities = 169/493 (34%), Positives = 276/493 (55%), Gaps = 16/493 (3%)
Query: 8 LKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLV 67
+ NP L+ F+ + +L+G A + T + D+ +GGR++ + ALSA +S S WL+
Sbjct: 3 VSNPT-LITFVIYIAAMVLIGLMAYRSTNNLSDYILGGRSLGSVVTALSAGASDMSGWLL 61
Query: 68 LGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRDT 126
+GL G Y G++ W A+G IV ++++ RLR +E +A+T+PDYF +RF D
Sbjct: 62 MGLPGAIYMSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDK 121
Query: 127 SKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFI 186
S +LRI ++++I++F T Y + AGA+ + G+S TAL I Y +GGF+
Sbjct: 122 SGLLRIISAVVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFIGGFL 181
Query: 187 AVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDP----KLINPWAFGAGVV 242
AV++ D ++A +MI L++ P+I + GG + + A DP L N G +
Sbjct: 182 AVSWTDTVQATLMIFALILTPIIVLLATGGVDTTFLAIEAKDPTSFDMLKNTTFIG---I 238
Query: 243 IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV-- 300
I +G G G GQPHI+ R+M+ D + + + W ++ G + VG G A
Sbjct: 239 ISLMGWGLGYFGQPHILARFMAADSVKSIAKARRISMTWMILCLGGTVAVGFFGIAYFSA 298
Query: 301 -PDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLY 359
P+V+ +N E ++ L+ F P + G+L+ I AA++ST QLLV +S + +D Y
Sbjct: 299 HPEVAGPVTENPERVFIELAKILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSALTEDFY 358
Query: 360 QEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTL 419
+ ++KG ++ + + R+ VLVV +A +A ++ + V +AW G GA+FGP +
Sbjct: 359 KAFLRKGA--SQRELVWVGRLMVLVVALIAIAMAANPENRVLGLVSYAWAGFGAAFGPVV 416
Query: 420 ILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITK 479
++S+ WK T+ G LAG++VG IT IVWK + + GLYE++P FIF+ +A VS +
Sbjct: 417 LISVIWKHMTRNGALAGILVGAITVIVWKHF--ELLGLYEIIPGFIFASLAIYFVSKMGA 474
Query: 480 PPENVEELMKAME 492
P + E A E
Sbjct: 475 PTLGMVERFDAAE 487
>sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|72512|pir||JGECPP
sodium/proline symporter - Escherichia coli
>gi|42602|emb|CAA29143.1| (X05653) putP proline carrier
(AA 1-502) [Escherichia coli]
>gi|1651504|dbj|BAA35793.1| (D90738) Proline carrier
protein [Escherichia coli] >gi|1787251|gb|AAC74100.1|
(AE000203) major sodium/proline symporter [Escherichia
coli K12] >gi|225963|prf||1404369A Pro carrier protein
[Escherichia coli]
Length = 502
Score = 312 bits (792), Expect = 4e-84
Identities = 171/473 (36%), Positives = 269/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S+ILRI
Sbjct: 68 VFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PVI + VGG + L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A D L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNDHPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+NAE ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRK--H 365
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
+K + + RV VLVV +A LA ++ + V +AW G GA+FGP ++ S+ W
Sbjct: 366 ASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK + GLYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGALTVIVWKQF--GWLGLYEIIPGFIFGSIGIVVFSLLGKAP 476
>gb|AAA24462.1| (L01133) proline permease [Escherichia coli]
Length = 489
Score = 312 bits (791), Expect = 6e-84
Identities = 170/473 (35%), Positives = 269/473 (55%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S+ILRI
Sbjct: 68 VFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PVI + VGG + L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV---PDVSQLPG 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A P V+
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNEHPSVAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+NAE ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRK--H 365
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
+K + + RV VLVV +A LA ++ + V +AW G GA+FGP ++ S+ W
Sbjct: 366 ASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK + GLYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGALTVIVWKQF--GWLGLYEIIPGFIFGSIGIVVFSLLGKAP 476
>gb|AAA24461.1| (L01132) proline permease [Escherichia coli]
>gi|147447|gb|AAA24467.1| (L01154) proline permease
[Escherichia coli] >gi|147451|gb|AAA24469.1| (L01156)
proline permease [Escherichia coli]
Length = 489
Score = 312 bits (791), Expect = 6e-84
Identities = 170/473 (35%), Positives = 270/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S+ILRI
Sbjct: 68 VFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PVI + VGG + L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV---PDVSQLPG 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A P V+
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNEHPAVAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+NAE ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K +
Sbjct: 308 QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRK--Q 365
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
+K + + RV VLVV +A LA ++ + V +AW G GA+FGP ++ S+ W
Sbjct: 366 ASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK + GLYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGALTVIVWKQF--GWLGLYEIIPGFIFGSIGIVVFSLLGKAP 476
>gb|AAA24466.1| (L01153) proline permease [Escherichia coli]
>gi|147453|gb|AAA24470.1| (L01157) proline permease
[Escherichia coli] >gi|147455|gb|AAA24471.1| (L01158)
proline permease [Escherichia coli]
>gi|147457|gb|AAA24472.1| (L01159) proline permease
[Escherichia coli]
Length = 489
Score = 311 bits (789), Expect = 1e-83
Identities = 170/473 (35%), Positives = 269/473 (55%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S+ILRI
Sbjct: 68 VFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PVI + VGG + L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV---PDVSQLPG 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A P V+
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNEHPAVAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+NAE ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRK--H 365
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
+K + + RV VLVV +A LA ++ + V +AW G GA+FGP ++ S+ W
Sbjct: 366 ASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK + GLYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGALTVIVWKQF--GWLGLYEIIPGFIFGSIGIVVFSLLGKAP 476
>pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9658517|gb|AAF96965.1|
(AE004432) sodium/proline symporter [Vibrio cholerae]
Length = 496
Score = 311 bits (788), Expect = 1e-83
Identities = 163/482 (33%), Positives = 269/482 (54%), Gaps = 11/482 (2%)
Query: 8 LKNPVALVA-FLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWL 66
++N A+ F+ LIL + +G YA +RTK+ D+F+GGR++ ALSA +S S WL
Sbjct: 1 MENSFAITTTFIVYLILMLAIGVYAYQRTKNSADYFLGGRSLGPWPAALSAGASDMSGWL 60
Query: 67 VLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDT 126
+LGL G AY G+ + W A G +V ++ RLR +S +++T+P++ RF D
Sbjct: 61 LLGLPGYAYAAGIESFWLAGGLLVGTWANWLVNAKRLRTYSITTDSLTLPEFLSRRFNDN 120
Query: 127 SKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFI 186
SK+++ ++ I++F Y + AG K T G+ TA++I + ++ Y + GGF+
Sbjct: 121 SKLIQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLDYSTAVIIGTVCVVSYTLFGGFL 180
Query: 187 AVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAG------ 240
AV++ D+++ ++M L+++P+ A+ GG ++ L A++P+L+ W G
Sbjct: 181 AVSWTDLVQGLLMAAALMIVPIAAMN--GGFTQLNHDLAAINPELLTLWNDAKGEPLSAI 238
Query: 241 VVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV 300
+I + G G GQPHI+ R+ + L + + W + GAI VGL G V
Sbjct: 239 AIISLVAWGLGYFGQPHILARFKASRSNKDLITARRIAVVWTGLSMAGAILVGLTGLIFV 298
Query: 301 PDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQ 360
+ + E I+ L F P++ GIL+ I AAI+STADSQLLV +S + +D Y+
Sbjct: 299 TQSGTIGLDDGEKIFMLLVNSLFHPVIAGILLAAILAAIMSTADSQLLVSSSALAEDFYK 358
Query: 361 EVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLI 420
+V K T + + + R+ V+++ +A LA + V +AW G GA+FGP L+
Sbjct: 359 QVFK--TDASSEDIVRVGRIAVILISLIALFLAMTPDSSVLGLVSYAWAGFGAAFGPALV 416
Query: 421 LSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKP 480
LSLYW + G L+G+IVG +T +VWK +YE+VP I S ++ ++VS++T
Sbjct: 417 LSLYWPRMNRHGALSGIIVGGVTIVVWKQLSGGWFDVYEIVPGIILSTLSIVVVSLLTGE 476
Query: 481 PE 482
P+
Sbjct: 477 PD 478
>gb|AAA24468.1| (L01155) proline permease [Escherichia coli]
Length = 489
Score = 311 bits (788), Expect = 1e-83
Identities = 170/473 (35%), Positives = 269/473 (55%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S+ILRI
Sbjct: 68 VFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PVI + VGG + L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV---PDVSQLPG 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A P V+
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNEHPAVAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+NAE ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFMRK--H 365
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
+K + + RV VLVV +A LA ++ + V +AW G GA+FGP ++ S+ W
Sbjct: 366 ASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK + GLYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGALTVIVWKQF--GWLGLYEIIPGFIFGSIGIVVFSLLGKAP 476
>pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946673|gb|AAG04172.1|AE004513_4 (AE004513)
sodium/proline symporter PutP [Pseudomonas aeruginosa]
Length = 506
Score = 308 bits (780), Expect = 1e-82
Identities = 166/480 (34%), Positives = 266/480 (54%), Gaps = 8/480 (1%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWL 66
M N L+ F+ + +L+G A + T + D+ +GGR++ ALSA +S S WL
Sbjct: 1 MSVNTPTLITFVIYIAAMVLIGLAAYRSTNNFSDYILGGRSLGSFVTALSAGASDMSGWL 60
Query: 67 VLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRD 125
++GL G Y G++ W A+G IV ++++ RLR +E NA+T+PDYF RF D
Sbjct: 61 LMGLPGAVYLSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGNALTLPDYFTNRFED 120
Query: 126 TSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGF 185
S++LRI ++++I++F T Y + AGA+ + G+S TAL I Y +GGF
Sbjct: 121 NSRLLRIFSALVILVFFTIYCASGIVAGARLFESTFGLSYETALWAGAAATIAYTFIGGF 180
Query: 186 IAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGV-VIG 244
+AV++ D ++A +MI L++ PVI + GG E + D + + + VI
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVMLATGGVEPTFTAIELKDATSFDMLKGASFIGVIS 240
Query: 245 FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV---P 301
+ G G GQPHI+ R+M+ D + + + W ++ GA+ VG G A P
Sbjct: 241 LMAWGLGYFGQPHILARFMAADSVKSIPAARRISMTWMILCLGGAVAVGFFGIAYFQAHP 300
Query: 302 DVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQE 361
+ + +N E ++ L+ F P + G+L+ I AA++ST QLLV +S + +D Y+
Sbjct: 301 EQAGAVSENPERVFIELAKILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSALTEDFYKA 360
Query: 362 VIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLIL 421
++KG + + + R VL+V +A LA ++ + V +AW G GA+FGP ++
Sbjct: 361 FLRKGA--SQLELVWVGRAMVLLVAVIAIWLASNPENRVLGLVSYAWAGFGAAFGPLVLF 418
Query: 422 SLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
SL WK T+ G LAGMIVG T I+WK L TGLYE++P F+F+ +A ++ S++ K P
Sbjct: 419 SLLWKRMTRNGALAGMIVGAATVILWK-NLLGWTGLYEIIPGFLFASVAIVVFSLLGKAP 477
>gb|AAA99282.1| (L01140) proline permease [Salmonella sp.]
>gi|154302|gb|AAA99283.1| (L01141) proline permease
[Salmonella sp.]
Length = 489
Score = 308 bits (780), Expect = 1e-82
Identities = 166/473 (35%), Positives = 268/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF +RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTSRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLTGAVAVGFFGIAFFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -GQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF I +I S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSIGIVIFSLLGKAP 476
>gb|AAA99288.1| (L01146) proline permease [Salmonella sp.]
>gi|154314|gb|AAA99289.1| (L01147) proline permease
[Salmonella sp.]
Length = 489
Score = 308 bits (780), Expect = 1e-82
Identities = 167/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPNNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLELYEIIPGFIFGSIGIVVFSLLGKAP 476
>gb|AAA99291.1| (L01149) proline permease [Salmonella sp.]
Length = 489
Score = 307 bits (779), Expect = 1e-82
Identities = 166/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVTYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSIGIVLFSLLGKAP 476
>gb|AAA99290.1| (L01148) proline permease [Salmonella sp.]
Length = 489
Score = 307 bits (779), Expect = 1e-82
Identities = 166/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVTYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF I ++ S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSIVIVLFSLLGKAP 476
>sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)
>gi|47849|emb|CAA36802.1| (X52573) proline permease (AA
1-502) [Salmonella typhimurium]
Length = 502
Score = 307 bits (778), Expect = 2e-82
Identities = 166/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF + +I S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSLGIVIFSLLGKAP 476
>gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi]
Length = 489
Score = 307 bits (778), Expect = 2e-82
Identities = 166/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF + +I S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSLGIVIFSLLGKAP 476
>gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium]
Length = 489
Score = 307 bits (778), Expect = 2e-82
Identities = 166/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF + +I S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSLGIVIFSLLGKAP 476
>gb|AAA99279.1| (L01137) proline permease [Salmonella sp.]
Length = 489
Score = 307 bits (777), Expect = 3e-82
Identities = 166/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF I +I S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSIGIVIFSLLGKAP 476
>gb|AAA99281.1| (L01139) proline permease [Salmonella sp.]
Length = 489
Score = 307 bits (777), Expect = 3e-82
Identities = 165/473 (34%), Positives = 268/473 (55%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F ++ +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF + ++ S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSMGIVVFSLLGKAP 476
>gb|AAA99278.1| (L01136) proline permease [Salmonella sp.]
Length = 489
Score = 307 bits (777), Expect = 3e-82
Identities = 166/473 (35%), Positives = 267/473 (56%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF I +I S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSIGIVIFSLLGKAP 476
>emb|CAA70363.1| (Y09163) proline transport system [Corynebacterium glutamicum]
Length = 524
Score = 306 bits (776), Expect = 3e-82
Identities = 165/502 (32%), Positives = 284/502 (55%), Gaps = 22/502 (4%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWL 66
M N ++A + +++ +L+G+++ ++T+ +D+ + GR ++ A+SA +S S WL
Sbjct: 1 MSDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWL 60
Query: 67 VLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRD 125
++GL G + G++ +W AVG + ++++ RLR +SE N+IT+P +FE R RD
Sbjct: 61 LMGLPGALFVTGMSELWIAVGLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRD 120
Query: 126 TSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGF 185
S+ LRI A++III+F T Y+ + AG + G + I + ++Y +GGF
Sbjct: 121 KSRALRIIAALIIIVFFTFYISSGMVAGGVYWESTFGGDYLLGMAIVAGVTVLYTFIGGF 180
Query: 186 IAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALD-----PKLINPWAF--- 237
+AV+Y D ++ IM L+++PV+A + ++ ++ D + NP F
Sbjct: 181 LAVSYTDAVQGTIMFFSLIIVPVMAYFALANPMDIWSFANSNDYGPHTDGIGNPTYFSMI 240
Query: 238 ---GAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGL 294
A +IG LG G G GQPHI+VR+M++ P + + +G W ++ GA F +
Sbjct: 241 SGISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGATFTAI 300
Query: 295 AGRAIV---PDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVA 351
PD + + E I+ L+ F P++ G+++ + AAI+ST SQLLV A
Sbjct: 301 ISTVFFAQNPDANITDTRAYESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVTA 360
Query: 352 STVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGL 411
S++++DL +V+KK + + E+T + +SR TV+++ +AA +A D I V FAW G
Sbjct: 361 SSLIEDLL-KVVKKDS-LSERTLIMLSRATVIILAIIAAAMAINPSDSILGLVGFAWAGF 418
Query: 412 GASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITG-LYELVPAFIFSLIA 470
G++FGP ++ SLYWK G ++GMI G I +I W + P++ LYE++P F + I
Sbjct: 419 GSAFGPIILASLYWKRLNAAGAISGMITGAIVSIAWG--MSPLSDTLYEIIPGFALATIV 476
Query: 471 TIIVSMITKPPENVEELMKAME 492
++VS++TK P EE++ E
Sbjct: 477 MVVVSLLTKEPS--EEILNEFE 496
>pir||S10220 sodium/proline symporter - Salmonella typhimurium
Length = 502
Score = 306 bits (776), Expect = 3e-82
Identities = 165/471 (35%), Positives = 267/471 (56%), Gaps = 9/471 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F + IL+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y G+ AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCGSGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST Q+LV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQMLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITK 479
T+ G LAGMI+G +T IVWK Y LYE++P FIF + +I S++ K
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSLGIVIFSLLGK 474
>gb|AAA99286.1| (L01144) proline permease [Salmonella sp.]
>gi|154310|gb|AAA99287.1| (L01145) proline permease
[Salmonella sp.]
Length = 489
Score = 306 bits (776), Expect = 3e-82
Identities = 165/473 (34%), Positives = 268/473 (55%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F ++ +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALVAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF + ++ S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSMGIVVFSLLGKEP 476
>gb|AAA99280.1| (L01138) proline permease [Salmonella sp.]
Length = 489
Score = 305 bits (774), Expect = 6e-82
Identities = 165/473 (34%), Positives = 267/473 (55%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F ++ +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHYSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + GIL+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF + ++ S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSMGIVVFSLLGKAP 476
>gb|AAA99284.1| (L01142) proline permease [Salmonella sp.]
>gi|154306|gb|AAA99285.1| (L01143) proline permease
[Salmonella sp.]
Length = 489
Score = 305 bits (774), Expect = 6e-82
Identities = 164/473 (34%), Positives = 268/473 (55%), Gaps = 9/473 (1%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F ++ +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRI 132
+ G++ W A+G + + + RLR +E NA+T+PDYF RF D S++LRI
Sbjct: 68 IFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLRI 127
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++++I++F T Y + AGA+ + G+S TAL I+Y +GGF+AV++ D
Sbjct: 128 ISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWTD 187
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFG 251
++A +MI L++ PV+ + VGG E L+V+ + ++ +I +G G G
Sbjct: 188 TVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLNFVAIISLMGWGLG 247
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG--- 308
GQPHI+ R+M+ D + + + + W ++ GA+ VG G A + L G
Sbjct: 248 YFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNNNPALAGAVN 307
Query: 309 KNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTK 368
+N+E ++ L+ F P + G+L+ I AA++ST QLLV +S + +DLY+ ++K
Sbjct: 308 QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKSA- 366
Query: 369 IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGT 428
++ + + RV VLVV +A LA + + V +AW G GA+FGP ++ S+ W
Sbjct: 367 -SQQELVWVGRVMVLVVALVAIALAANPDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRM 425
Query: 429 TKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
T+ G LAGMI+G +T IVWK Y LYE++P FIF + ++ S++ K P
Sbjct: 426 TRNGALAGMIIGAVTVIVWKQY--GWLDLYEIIPGFIFGSMGIVVFSLLGKAP 476
>pir||A71980 sodium/proline symporter - Helicobacter pylori (strain J99)
>gi|4154554|gb|AAD05631.1| (AE001444) sodium/proline
symporter [Helicobacter pylori J99]
Length = 496
Score = 304 bits (771), Expect = 1e-81
Identities = 170/488 (34%), Positives = 278/488 (56%), Gaps = 8/488 (1%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWL 66
+L P+ + +++L++ + +GFY K+ ++ ED+F+G R+M + ALSA +S S WL
Sbjct: 5 VLSTPIVTMFVVYSLLM-LYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWL 63
Query: 67 VLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRD 125
++GL G Y G+ A+G + + +V++ RLR ++ N+IT+ DYFE RF D
Sbjct: 64 LMGLPGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSD 123
Query: 126 TSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGF 185
ILR+ ++ +I+IF Y+ + +GAK GI AL I L+I+ Y LGG+
Sbjct: 124 DKHILRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGY 183
Query: 186 IAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVV--I 243
AV + D+I+ ++M+ L+V+P++ + +GG E +K++ + P+ ++ + G+ VV I
Sbjct: 184 KAVCWTDLIQGLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLS-FLQGSSVVAII 242
Query: 244 GFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDV 303
L G G GQPHI+VR+MSI + +T +G W V+ GA +GL G A V
Sbjct: 243 SSLAWGLGYFGQPHILVRFMSIRSIRDVPKATTIGISWMVISLIGACVMGLLGVAYVHKF 302
Query: 304 SQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVI 363
L ++ E I+ +S F P + GIL+ I AA++STA SQLLV +ST+ +D Y +
Sbjct: 303 -DLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIF 361
Query: 364 KKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSL 423
K +K +TISR++VL V +A ++ I V +AW G GASFG ++ SL
Sbjct: 362 NKNA--PQKLVMTISRLSVLGVACIAFFISTDKNASILSIVSYAWAGFGASFGSVILFSL 419
Query: 424 YWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPPEN 483
+W T+ G +AGM+ G T I++ + K +YE+VP FI + +A + S+ +
Sbjct: 420 FWSRMTRIGAIAGMLSGASTVILYDKFGKSFLDIYEIVPGFIVASVAIVAFSLFSSVRSG 479
Query: 484 VEELMKAM 491
+E + M
Sbjct: 480 TKEAFETM 487
>pir||G64526 sodium/proline symporter - Helicobacter pylori (strain 26695)
>gi|2313133|gb|AAD07125.1| (AE000527) proline permease
(putP) [Helicobacter pylori 26695]
Length = 496
Score = 303 bits (769), Expect = 2e-81
Identities = 169/488 (34%), Positives = 278/488 (56%), Gaps = 8/488 (1%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWL 66
+L P+ + +++L++ + +GFY K+ ++ ED+F+G R+M + ALSA +S S WL
Sbjct: 5 VLSTPIVTMFIVYSLLM-LYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWL 63
Query: 67 VLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRD 125
++GL G Y G+ A+G + + +V++ RLR ++ N+IT+ DYFE RF D
Sbjct: 64 LMGLPGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSD 123
Query: 126 TSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGF 185
ILR+ ++ +I+IF Y+ + +GAK GI AL I L+I+ Y LGG+
Sbjct: 124 DKHILRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGY 183
Query: 186 IAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVV--I 243
AV + D+I+ ++M+ L+V+P++ + +GG E +K++ + P+ ++ + G+ VV I
Sbjct: 184 KAVCWTDLIQGLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLS-FLQGSSVVAII 242
Query: 244 GFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDV 303
L G G GQPHI+VR+MSI + +T +G W V+ GA +GL G A V
Sbjct: 243 SSLAWGLGYFGQPHILVRFMSIRSIRDVPKATTIGISWMVISLIGACVMGLLGVAYVHKF 302
Query: 304 SQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVI 363
L ++ E I+ +S F P + GIL+ I AA++STA SQLLV +ST+ +D Y +
Sbjct: 303 -DLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIF 361
Query: 364 KKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSL 423
K +K + ISR++VL V +A ++ I V +AW G GASFG ++ SL
Sbjct: 362 NKDA--PQKLVMAISRLSVLGVACIAFFISTDRNASILSIVSYAWAGFGASFGSVILFSL 419
Query: 424 YWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPPEN 483
+W T+ G +AGM+ G T I++ + K +YE+VP FI + +A ++ S+ +
Sbjct: 420 FWSRMTRIGAIAGMLSGASTVILYDKFGKSFLDIYEIVPGFIVASVAIVVFSLFSSVRTG 479
Query: 484 VEELMKAM 491
+E + M
Sbjct: 480 TKEAFETM 487
>gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus aureus]
Length = 497
Score = 300 bits (760), Expect = 2e-80
Identities = 167/477 (35%), Positives = 274/477 (57%), Gaps = 13/477 (2%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
++A F +++ L+ F + T + ++ +GGR++ ALSA +S S W+++GL G
Sbjct: 21 MIAVYFLILM--LLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGS 78
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRDTSKILRI 132
Y G++A+W +G + + + RLR ++E +AIT+PD+F+ R D + +L+I
Sbjct: 79 VYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKI 138
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
+ +II++F T Y + F +G K +A G+ L++ ++I Y GG++AV+ D
Sbjct: 139 ISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITD 198
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGV-VIGFLGIGFG 251
+ VIM+I +V++P++A+ + G V A+ P +N + + + +I G G
Sbjct: 199 FFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVA-AMKPTNLNLFKGLSFIGIISLFSWGLG 257
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGKNA 311
GQPHIIVR+MSI L + +G W V GA+ VGL G A VP + ++
Sbjct: 258 YFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVP-AYHIKLEDP 316
Query: 312 EMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVI-KKGTKID 370
E ++ +S F P++ G L+ I AAI+ST SQLLV +S++ +D Y+ + ++ K D
Sbjct: 317 ETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEKAKTD 376
Query: 371 EKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
+K + I R++VLVV +A +A+ D I V AW G GASF P ++ +LYWKG T+
Sbjct: 377 QKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTR 436
Query: 431 WGVLAGMIVGTITTIVWKLYLKP------ITGLYELVPAFIFSLIATIIVSMITKPP 481
G ++GM+ G + IVW ++KP I GLYE++P FI S+I T +VS +TK P
Sbjct: 437 AGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKP 493
>pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis
>gi|1805394|dbj|BAA08956.1| (D50453) homologue of
proline permease of E. coli [Bacillus subtilis]
>gi|2632608|emb|CAB12116.1| (Z99105) similar to proline
permease [Bacillus subtilis]
Length = 449
Score = 298 bits (754), Expect = 1e-79
Identities = 158/439 (35%), Positives = 255/439 (57%), Gaps = 12/439 (2%)
Query: 48 MDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFS 107
M ALSA ++ S WL++GL G + G++ W +G + ++Y+ RLR ++
Sbjct: 1 MGPAVTALSAGAADMSGWLLMGLPGAMFSTGLSGAWIVIGLCLGAWANWLYVAPRLRTYT 60
Query: 108 ERF-NAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIF 166
E+ N+IT+P + E RF D +K+LR+ + I+I++F T YV + +G ++ LG+
Sbjct: 61 EKAGNSITIPGFLENRFGDQTKLLRLFSGIVILVFFTFYVSSGMVSGGVLFNSILGMDYH 120
Query: 167 TALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHA 226
T L I +++ Y + GGF+AV++ D ++ +IM L+++P++ GG + + + +
Sbjct: 121 TGLWIVTGVVVAYTLFGGFLAVSWTDFVQGIIMFAALILVPIVTFFHTGGAGDTVAEIRS 180
Query: 227 LDPKLINPWAFGAGVVIGFLGI---GFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNV 283
+DP + N F V+G + + G G GQPHIIVR+M+I +++ + +G W +
Sbjct: 181 VDPDMFN--IFKGTSVLGIISLFAWGLGYFGQPHIIVRFMAITSVKEIKRARRIGMGWMI 238
Query: 284 VLAWGAIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTA 343
+ A GA+ GL G A + K+ E I+ L F PI+ G LI I AAI+ST
Sbjct: 239 LSAVGAVLTGLGGIAYYHQ-RGMTLKDPETIFIQLGNILFHPIITGFLISAILAAIMSTI 297
Query: 344 DSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWF 403
SQLLV +S++V+DLY+ + ++ +K + + R+ VL V +A +LA+ + I
Sbjct: 298 SSQLLVTSSSLVEDLYKSMFRRSA--SDKELVFLGRLAVLAVSIVALVLAWEKNNTILGL 355
Query: 404 VLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVW-KLYLKPITGLYELVP 462
V +AW G GASFGP ++LSL+WK TKWG LAGMIVG T I+W L LYE++P
Sbjct: 356 VSYAWAGFGASFGPVVLLSLFWKRMTKWGALAGMIVGAATVIIWANAGLSDF--LYEMIP 413
Query: 463 AFIFSLIATIIVSMITKPP 481
F SL++ VS++T+ P
Sbjct: 414 GFAASLLSVFFVSILTQAP 432
>pir||T48676 proline uptake protein [validated] - Staphylococcus aureus
>gi|2565311|gb|AAC38087.1| (AF024571) high affinity
proline permease [Staphylococcus aureus]
Length = 497
Score = 298 bits (754), Expect = 1e-79
Identities = 167/477 (35%), Positives = 273/477 (57%), Gaps = 13/477 (2%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
++A F +++ L+ F + T + ++ +GGR++ ALSA +S S W+++GL G
Sbjct: 21 MIAVYFLILM--LLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGS 78
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRDTSKILRI 132
Y G++A+W +G + + + RLR ++E +AIT+PD+F+ R D + +L+I
Sbjct: 79 VYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKI 138
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
+ +III+F T Y + F +G K +A G+ L++ ++I Y GG++AV+ D
Sbjct: 139 ISGLIIIVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITD 198
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGV-VIGFLGIGFG 251
+ VIM+I +V++P++A+ + G V A+ P +N + + + +I G G
Sbjct: 199 FFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVA-AMKPTNLNLFKGLSFIGIISLFSWGLG 257
Query: 252 SPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGKNA 311
GQPHIIVR+MSI L + +G W V GA+ VGL G A VP + ++
Sbjct: 258 YFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVP-AYHIKLEDP 316
Query: 312 EMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVI-KKGTKID 370
E ++ +S F P++ G L+ I AAI+ST SQLLV +S++ +D Y+ + ++ K
Sbjct: 317 ETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEKAKTH 376
Query: 371 EKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
+K + I R++VLVV +A +A+ D I V AW G GASF P ++ +LYWKG T+
Sbjct: 377 QKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTR 436
Query: 431 WGVLAGMIVGTITTIVWKLYLKP------ITGLYELVPAFIFSLIATIIVSMITKPP 481
G ++GM+ G + IVW ++KP I GLYE++P FI S+I T +VS +TK P
Sbjct: 437 AGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKP 493
>gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomonas putida]
>gi|8132050|gb|AAF73192.1|AF151964_1 (AF151964) proline
permease [Pseudomonas putida]
Length = 492
Score = 296 bits (750), Expect = 4e-79
Identities = 155/488 (31%), Positives = 274/488 (55%), Gaps = 10/488 (2%)
Query: 10 NPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
NP+ + F+ + +L+GF A + T + D+ +GGR++ + ALSA +S S WL++G
Sbjct: 3 NPLT-ITFVIYIAAMVLIGFAAYRATNNLSDYILGGRSLGSVVTALSAGASDMSGWLLMG 61
Query: 70 LSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERF-NAITVPDYFEARFRDTSK 128
L G Y G++ W A+G V ++++ RLR +E +A+T+PDYF +RF D S
Sbjct: 62 LPGAIYFAGLSEAWIAIGLTVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDNSG 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
+LRI ++I+I++F T Y + AGA+ + G+S TAL I Y +GGF+AV
Sbjct: 122 LLRIISAIVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFVGGFLAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGV-VIGFLG 247
++ D ++A +MI L++ PVI + GG ++ + A++ + + + +I +G
Sbjct: 182 SWTDTVQASLMIFALILTPVIVLISTGGFDQTFAAIEAVNRRNFDMLKGATFIGIISLMG 241
Query: 248 IGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV---PDVS 304
G G PHI+ R+M+ D N + + + W ++ G VG G A P+++
Sbjct: 242 WGLGYFRPPHILARFMAADSVNSIAKARRISMTWMILCLAGTCAVGFCGIAYFSAHPELA 301
Query: 305 QLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIK 364
+N + ++ L+ F P + G+L+ I AA++ T QLLV +S + ++ Y+ ++
Sbjct: 302 GPVSENHKRVFIELAKILFNPWVAGVLLSAILAAVMITLSCQLLVCSSALTENFYKAFLR 361
Query: 365 KGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLY 424
K + + + R+ VL V +A +A ++ + V +AW G GA+FGP +++S+
Sbjct: 362 KNA--SQVELVWVGRLMVLAVALIAIAMAANPENRVLGLVAYAWAGFGAAFGPVVLISVL 419
Query: 425 WKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKPPENV 484
WKG T+ G LAG++VG +T I+WK + GLYE++P F+F+ IA ++VS + P + +
Sbjct: 420 WKGMTRNGALAGIVVGALTVILWKNF--DTLGLYEIIPGFLFASIAIVLVSKLGSPSQTM 477
Query: 485 EELMKAME 492
+ +A +
Sbjct: 478 VKRFEAAD 485
>sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|1075316|pir||E64118
sodium/proline symporter - Haemophilus influenzae
(strain Rd KW20) >gi|1574814|gb|AAC22999.1| (U32814)
sodium/proline symporter (proline permease) (putP)
[Haemophilus influenzae Rd]
Length = 504
Score = 280 bits (709), Expect = 2e-74
Identities = 159/486 (32%), Positives = 258/486 (52%), Gaps = 22/486 (4%)
Query: 13 ALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSG 72
+L+ F + +L+G A T + D+ +GGR + A+SA +S S WL++GL G
Sbjct: 7 SLITFTIYIFGMLLIGVLAYYYTNNLSDYILGGRRLGSFVTAMSAGASDMSGWLLMGLPG 66
Query: 73 MAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRDTSKILR 131
Y G+ W A+G + F ++ + RLR ++E NA+T+P+YF RF + K+L+
Sbjct: 67 AVYLSGLVEGWIAIGLTIGAYFNWLLVAGRLRVYTELNNNALTLPEYFHNRFGSSHKLLK 126
Query: 132 IAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYN 191
+ ++ II++FLT Y + AGAK + TAL I Y +GGF+AV++
Sbjct: 127 LVSATIILVFLTIYCASGVVAGAKLFQNIFSVEYSTALWYGAAATIAYTFIGGFLAVSWT 186
Query: 192 DVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWA--FGAGVVIGFLGI- 248
D I+A +MI L++ PV + T + VL + + + F + +G L +
Sbjct: 187 DTIQATLMIFALILTPVFVLLSFADTAQFSAVLEQAEAAVNKDFTDLFTSTTPLGLLSLA 246
Query: 249 --GFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGL-------AGRAI 299
G G GQPHI+ R+M+ D L + + W V+ GAI +GL A AI
Sbjct: 247 AWGLGYFGQPHILARFMAADSVKSLIKARRISMGWMVLCLAGAIGIGLFAIPYFFANPAI 306
Query: 300 VPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLY 359
V++ P E ++ L+ F P + GIL+ I AA++ST +QLL+ +S++ +D Y
Sbjct: 307 AGTVNREP----EQVFIELAKLLFNPWIAGILLSAILAAVMSTLSAQLLISSSSITEDFY 362
Query: 360 QEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTL 419
+ I+ EK + + R+ VLV+ LA +A + V FAW G G++FGP +
Sbjct: 363 KGFIRPNA--SEKELVWLGRIMVLVIAALAIWIAQDENSKVLKLVEFAWAGFGSAFGPVV 420
Query: 420 ILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITG---LYELVPAFIFSLIATIIVSM 476
+ SL+WK T G +AGM+VG +T WK + T +YE++P F F+ +A I++S+
Sbjct: 421 LFSLFWKRMTSSGAMAGMLVGAVTVFAWKEVVPADTDWFKVYEMIPGFAFASLAIIVISL 480
Query: 477 ITKPPE 482
++ PE
Sbjct: 481 LSNKPE 486
>pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisseria
meningitidis (group B strain MD58, group A strain Z2491)
>gi|7225624|gb|AAF40841.1| (AE002396) sodium/proline
symporter [Neisseria meningitidis MC58]
>gi|7380708|emb|CAB85299.1| (AL162758) sodium/proline
symporter [Neisseria meningitidis Z2491]
Length = 508
Score = 276 bits (698), Expect = 5e-73
Identities = 164/503 (32%), Positives = 268/503 (52%), Gaps = 26/503 (5%)
Query: 10 NPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
NP+ + F L+ +L+G A T++ +D+ +GGR++ A+SA +S S WL++G
Sbjct: 2 NPM-YITFAIYLVAVLLIGLAAYFSTRNFDDYILGGRSLGPFVTAMSAGASDMSGWLLMG 60
Query: 70 LSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFN-AITVPDYFEARFRDTSK 128
L G Y G+ W A+G +V F ++ + RLR +E N A+T+PDYF RF
Sbjct: 61 LPGAIYLSGLNEAWIAIGLLVGAYFNWLLVAGRLRVHTEYANNALTLPDYFFHRFGAGGH 120
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTAL-GISIFTALMISVLMIIVYMILGGFIA 187
++++ +++II+ F T Y + AGA + G++ A+ + I Y LGGF+A
Sbjct: 121 LMKVVSALIILFFFTIYCASGIVAGATLFQSLFEGMTYNQAMWLGAGATIAYTFLGGFLA 180
Query: 188 VAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWA--FGAGVVIGF 245
V++ D ++A +MI L++ PV+ +GG E++ + ++ + F VIG
Sbjct: 181 VSWTDTLQASLMIFALILTPVMVYLGLGGAEQMSAAIQSVAAGTGKEYGSLFAGTTVIGI 240
Query: 246 LGI---GFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV-- 300
+ G G GQPHI+ R+M+ + L + +G W + GA+ VG G A
Sbjct: 241 ISTAAWGLGYFGQPHILARFMAAESAKSLVSARRIGMTWMALCLAGAVAVGYFGIAYFGA 300
Query: 301 -PD-VSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDL 358
PD VS + G N E I+ LS F P + GI++ I AA++ST QLLV +S + +D
Sbjct: 301 NPDKVSSMSG-NHERIFIALSTLLFNPWIAGIILSAILAAVMSTLSCQLLVCSSAITEDF 359
Query: 359 YQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPT 418
Y+ ++K + E + + R+ VL + ++ ++A + V +AW G GA+FGP
Sbjct: 360 YKGFLRKNAQQSE--LVWVGRLMVLAIAVISILIASDPNSKVLGLVSYAWAGFGAAFGPI 417
Query: 419 LILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKP---------ITGLYELVPAFIFSLI 469
+ILS+ WK T +G L+GM+ G +T +VW ++K + +YE+VP FI LI
Sbjct: 418 VILSVLWKRITAYGALSGMVAGALTVVVWAEWVKKPAQAAGESGLLTMYEIVPGFIVCLI 477
Query: 470 ATIIVSMITKPP--ENVEELMKA 490
++VS+ K P E E KA
Sbjct: 478 VAVLVSLFNKEPSRETQERFEKA 500
>gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium sp. NRC-1]
Length = 522
Score = 260 bits (657), Expect = 3e-68
Identities = 154/465 (33%), Positives = 249/465 (53%), Gaps = 30/465 (6%)
Query: 40 DFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYM 99
D+ +GGR + + S +S S WL LG+ G AY G+ A + VG I A++ + +
Sbjct: 6 DYVIGGRDVGPVVTGFSERASEMSGWLTLGVPGDAYTTGIMAFYNGVGMIPADLAAWAGL 65
Query: 100 GIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLST 159
RLRK+SE A+T+P +F R D + +++ +S ++I+F SYVGAQ A L
Sbjct: 66 AKRLRKYSEIVRAVTLPTFFATRLNDDTGVVKAVSSFVLIVFEGSYVGAQIVAAGTLLRV 125
Query: 160 ALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVG-GTE 218
G+ ++ ++ ++++ Y +LGG+ AVA++D + I++ +LP+IA A G
Sbjct: 126 LTGVDMWVGIVAGGVIVVGYTMLGGYFAVAWSDYFQGAIILAAFAILPIIAYATWGLPFA 185
Query: 219 EVLKVLHALDPKLINPWAFGAGV---VIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVST 275
++ + + I A G +I + +G G PG PHI+VR+M ID +R +
Sbjct: 186 DLAAMDNGASLTSITGGATGWAALFGIISYAAVGLGIPGNPHIMVRFMGIDRVRNVRTAA 245
Query: 276 VVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG-KNAEMIYPYLSAQYFPPILYGILIGG 334
VV + V GA VGL ++Q G +N + P ++ + P + G+++
Sbjct: 246 VVAQLFMFVAYIGAALVGLYA------LTQFGGLENTDNAMPLVTLELLPSAVAGVVLAA 299
Query: 335 IFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAY 394
AA++S+ADSQLLV S VV+D+Y + + + E + SR L +GF + AY
Sbjct: 300 ALAAMMSSADSQLLVATSAVVEDVYHGFLNE--QATEAQLVRYSRYVTLAIGFASIGFAY 357
Query: 395 VAKDI-IFWFVL-FAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLY-- 450
VA++ I+ VL +AWGGLGA+ GP LI L+W+ T G +A M+ GT T I+W +
Sbjct: 358 VARNTPIYELVLNYAWGGLGAALGPLLIAVLWWRRVTAAGAVASMVTGTATMILWTQWPT 417
Query: 451 -LKPIT------------GLYELVPAFIFSLIATIIVSMITKPPE 482
L P T +Y L PAF+ S + ++VS++T PP+
Sbjct: 418 ILGPETVNSFHPAVSGMLTVYGLFPAFVVSAVVLVVVSLLTTPPD 462
>pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococcus abyssi
(strain Orsay) >gi|5458333|emb|CAB49822.1| (AJ248285)
OSMOREGULATED PROLINE TRANSPORTER [Pyrococcus abyssi]
Length = 484
Score = 248 bits (627), Expect = 1e-64
Identities = 151/482 (31%), Positives = 251/482 (51%), Gaps = 31/482 (6%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
L +F L I VG Y ++ KS +DF + GR + ALS ++G S+W +LGL G
Sbjct: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133
A+ G+ A+W A+G ++ + + RLRK +E+++A+T DY R + K +RI
Sbjct: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127
Query: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193
S I F YVGAQ+ G K L+T G+ ++I+ L+I+ Y ++GG +VAY D
Sbjct: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187
Query: 194 IRAVIMIIGLVVLPVIAVAKVGGTEEV--LKVLHALD------PKLINPWAFGAGVV--- 242
++A++MI+ L+V P++ V + E+ V AL ++ A A +V
Sbjct: 188 VQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVI 247
Query: 243 ------IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAG 296
G+LG G P + +R+M+I D +++ +G W ++ GA+ +G G
Sbjct: 248 AEFSWFFGYLG------GMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIG 301
Query: 297 RAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVK 356
AI K+ E + P + + FPP L + I G AA+LSTADS L++ ++ +
Sbjct: 302 IAIFGPNGL---KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSE 358
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVA-KDIIFWFVLFAWGGLGASF 415
++ + I K + D + +L +SR+T + +G +A I+AYV +I+ V + W G+G +F
Sbjct: 359 NILKPYIYK-NEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTF 417
Query: 416 GPTLILSLYWKGTTKWGVLAGMIVGTITTIVW---KLYLKPITGLYELVPAFIFSLIATI 472
+IL+L+WK V +I G + T+ W L K L + FI ++IAT
Sbjct: 418 SVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATY 477
Query: 473 IV 474
+
Sbjct: 478 AI 479
>pir||D65118 pantothenate permease [validated] - Escherichia coli
>gi|606198|gb|AAA58061.1| (U18997) pantothenate permease
[Escherichia coli] >gi|1789656|gb|AAC76290.1| (AE000404)
sodium/pantothenate symporter [Escherichia coli K12]
Length = 485
Score = 221 bits (558), Expect = 1e-56
Identities = 145/470 (30%), Positives = 243/470 (50%), Gaps = 23/470 (4%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSE---EDFFVGGRAMDKITVALSAVSSGRSSWLVLGL 70
LVA+L ++ + YAM++ + ++F+G R+M I +A++ ++ S+ +G
Sbjct: 11 LVAYL---VVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISASSFIGG 67
Query: 71 SGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKIL 130
G AYK G+ V A+ + A +G + + R+NA+T+ D AR++ S++L
Sbjct: 68 PGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ--SRLL 125
Query: 131 RIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAY 190
AS+ +++ + QF GA+ L TA GI T L+I + I +Y GGF A
Sbjct: 126 VWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFRASVL 185
Query: 191 NDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIG------ 244
ND ++ ++M+IG VVL + V GG ++ L +DP+L+ P GA ++
Sbjct: 186 NDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQTIDPQLVTPQ--GADDILSPAFMTS 243
Query: 245 -FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDV 303
++ + FG G PH VR +S D + ++GT +L +G G GRA++PD+
Sbjct: 244 FWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIGTIVVAILMFGMHLAGALGRAVIPDL 303
Query: 304 SQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVI 363
+ +++ P L + PP GI + AAI+ST ++QLL ++T++KDLY I
Sbjct: 304 TV-----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKDLYLN-I 357
Query: 364 KKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSL 423
+ +E +S V LV+G L + A+ ++I W L A+GGL A F L+L L
Sbjct: 358 RPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMIIWLNLLAFGGLEAVFLWPLVLGL 417
Query: 424 YWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATII 473
YW+ G L+ MIVG + V G + +VP+ + SL+A ++
Sbjct: 418 YWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSLLAFLV 467
>sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE)
Length = 483
Score = 221 bits (558), Expect = 1e-56
Identities = 145/470 (30%), Positives = 243/470 (50%), Gaps = 23/470 (4%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSE---EDFFVGGRAMDKITVALSAVSSGRSSWLVLGL 70
LVA+L ++ + YAM++ + ++F+G R+M I +A++ ++ S+ +G
Sbjct: 9 LVAYL---VVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISASSFIGG 65
Query: 71 SGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKIL 130
G AYK G+ V A+ + A +G + + R+NA+T+ D AR++ S++L
Sbjct: 66 PGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ--SRLL 123
Query: 131 RIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAY 190
AS+ +++ + QF GA+ L TA GI T L+I + I +Y GGF A
Sbjct: 124 VWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFRASVL 183
Query: 191 NDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIG------ 244
ND ++ ++M+IG VVL + V GG ++ L +DP+L+ P GA ++
Sbjct: 184 NDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQTIDPQLVTPQ--GADDILSPAFMTS 241
Query: 245 -FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDV 303
++ + FG G PH VR +S D + ++GT +L +G G GRA++PD+
Sbjct: 242 FWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIGTIVVAILMFGMHLAGALGRAVIPDL 301
Query: 304 SQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVI 363
+ +++ P L + PP GI + AAI+ST ++QLL ++T++KDLY I
Sbjct: 302 TV-----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKDLYLN-I 355
Query: 364 KKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSL 423
+ +E +S V LV+G L + A+ ++I W L A+GGL A F L+L L
Sbjct: 356 RPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMIIWLNLLAFGGLEAVFLWPLVLGL 415
Query: 424 YWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATII 473
YW+ G L+ MIVG + V G + +VP+ + SL+A ++
Sbjct: 416 YWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSLLAFLV 465
>sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE)
>gi|1075105|pir||H64105 pantothenate transport protein -
Haemophilus influenzae (strain Rd KW20)
>gi|1574003|gb|AAC22634.1| (U32778) sodium/pantothenate
symporter (panF) [Haemophilus influenzae Rd]
Length = 484
Score = 219 bits (552), Expect = 6e-56
Identities = 139/472 (29%), Positives = 242/472 (50%), Gaps = 30/472 (6%)
Query: 21 LILPILVG---------FYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+ILP+++ F +KRTK + +++VG R+M +A++ S+ S+ +G
Sbjct: 5 IILPLIIYLTFVFGAAIFAYVKRTKGDFLTEYYVGNRSMTGFVLAMTTASTYASASSFVG 64
Query: 70 LSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKI 129
G AYK G+ V A+ + +G + S NA+T+ D F R+++ K
Sbjct: 65 GPGAAYKYGLGWVLLAMIQVPVVWLALGALGKKFALLSRETNALTINDLFFYRYKN--KY 122
Query: 130 LRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVA 189
L +S+ +++ + + QF GA+ L T +GIS AL++ L + +Y +GGF AV
Sbjct: 123 LVWLSSLALLLAFFAAMTVQFIGGARLLETTIGISYTQALLLFALTVGIYTFIGGFRAVV 182
Query: 190 YNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIGFLG-- 247
D I+ +MI G ++L + + +GG E + L +DP L+ P+ + F+
Sbjct: 183 LTDTIQGTVMIFGTIILLIGTIYALGGVESAVNKLTEIDPDLVTPYGPNGMLDFQFMASF 242
Query: 248 ---IGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVS 304
+ FG G PH VR M+ D L ++GT ++ G G GRA++P+++
Sbjct: 243 WILVCFGVVGLPHTAVRCMAFKDSKALHRGMLIGTIVLSIIMLGMHLAGALGRAVIPNLT 302
Query: 305 QLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIK 364
++ + P L + PPI+ GI + +AI+ST D+QL+ +S VKDLY
Sbjct: 303 V-----SDQVIPTLMIKVLPPIVAGIFLAAPMSAIMSTIDAQLIQSSSIFVKDLYLSAKP 357
Query: 365 KGTKIDEKTALTISRVTVLVVGFLAAILAYVA---KDIIFWFVLFAWGGLGASFGPTLIL 421
+ K ++K + S +T++ L A+L + A D+I W LFA+GGL A+F ++L
Sbjct: 358 EAAKNEKKVSYFSSIITLI----LTALLIFAALNPPDMIIWLNLFAFGGLEAAFLWVIVL 413
Query: 422 SLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATII 473
+YW +G L+ MI+G + I+ + +++VP+ +F LIA ++
Sbjct: 414 GIYWDKANAYGALSSMIIGLGSYILLTQLGIKLFNFHQIVPSLVFGLIAFLV 465
>pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|gb|AAA24276.1|
(M30953) pantothenate permease (panF) [Escherichia coli]
Length = 482
Score = 189 bits (475), Expect = 6e-47
Identities = 138/471 (29%), Positives = 234/471 (49%), Gaps = 26/471 (5%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSE---EDFFVGGRAMDKITVALSAVSSGRSSWLVLGL 70
LVA+L ++ + YAM++ + ++F+G R+M I +A++ ++ S+ +G
Sbjct: 9 LVAYL---VVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISASSFIGG 65
Query: 71 SGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKIL 130
G AYK G+ V A+ + A +G + + R+NA+T+ D AR++ S++L
Sbjct: 66 PGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ--SRLL 123
Query: 131 RIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAY 190
AS+ +++ + QF GA+ L TA GI T L+I + I +Y GGF A
Sbjct: 124 VWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFAPAAE 183
Query: 191 NDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIG------ 244
RA + GG ++ L +DP+L+ P GA ++
Sbjct: 184 RHHARACDADWHRCAAYWRSTC-AGGLSNAVQTLQTIDPQLVTPQ--GADDILSPAFMTS 240
Query: 245 -FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDV 303
++ + FG G H VR +S D + ++GT +L +G G GRA++PD+
Sbjct: 241 FWVLVCFGVIGLAHTAVRCISYKDSKAVHRGIIIGTIVVAILMFGMHLAGALGRAVIPDL 300
Query: 304 SQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVI 363
+P +++ P L + PP GI + AAI+ST ++QLL ++T++KDLY +
Sbjct: 301 -HVP----DLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKDLYLNI- 354
Query: 364 KKGTKIDEKTALT-ISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILS 422
+ ++ +T L +S V LV+G L + A+ ++I W L A+GGL A F L+L
Sbjct: 355 -RPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMIIWLNLLAFGGLEAVFLWPLVLG 413
Query: 423 LYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATII 473
LYW+ G L+ MIVG + V G + +VP+ + SL+A ++
Sbjct: 414 LYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSLLAFLV 464
>pir||C69115 sodium/proline symporter (proline permease) - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622992|gb|AAB86322.1| (AE000938) sodium/proline
symporter (proline permease) [Methanobacterium
thermoautotrophicum]
Length = 526
Score = 176 bits (442), Expect = 5e-43
Identities = 120/461 (26%), Positives = 216/461 (46%), Gaps = 32/461 (6%)
Query: 15 VAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMA 74
+ L +L VG+ A +RT++ ED+ V GR +A+S ++ S+ ++G GMA
Sbjct: 8 IVVLIYFLLVGYVGYVAWRRTETSEDYMVAGRRTHPYIMAMSYGATFISTAAIVGFGGMA 67
Query: 75 YKMGVTAVWAAVGYIVAEMF-QFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133
G+ +W I+ +F FV+ G R K +A+T P++ RF S+ L+
Sbjct: 68 GVFGMGILWLVFLNILVGIFIAFVFFGKRTMKMGHNMSALTFPEFLGRRFN--SRFLQYF 125
Query: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193
II + + Y A+ + T LG+ AL++ +++ VY++LGG V Y D
Sbjct: 126 GGAIIFLGMPLYASVVLIGAARFIETTLGLDFSIALILMAVIVAVYVVLGGIRGVMYTDA 185
Query: 194 IRAVIMIIGLVVLPVIAVAKVGGT----EEVLKVLHALDPK--LINPWAFGAGVVIG--- 244
++ IM +G++ L V +GG + + + H + K I + + + G
Sbjct: 186 LQGTIMFLGMIFLVVSTYYLLGGVVDAHQALTNISHLIPAKARAIGATGWTSMPLYGSPY 245
Query: 245 --------FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAG 296
LG+G G QP +IVR+M++ +L ++G + V+ W A VG
Sbjct: 246 WWTLLSTIILGVGVGVLAQPQLIVRFMTVKSNRELNRGVLIGALFIFVMTWSAYVVGALS 305
Query: 297 -----RAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVA 351
R + Q G NA+ I P+ P I + + +A +ST +Q V
Sbjct: 306 NVYFFRKMGMIAVQAAGGNADKIIPFFIKSAMPEWFSYIFMLTLLSAAMSTLSAQFHVQG 365
Query: 352 STVVKDLYQEV-IKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAK-DIIFWFVLFAWG 409
+ + +D+Y+ V +KG + ++ I+R +++ +A +L Y+ I+ +G
Sbjct: 366 TAIGRDVYETVRRRKGDR-----SVLITRGGIIIAVLIAVVLGYLLPGSIVAQGTALFFG 420
Query: 410 GLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLY 450
ASF + +++WK T+ G +AGM+ G I ++ W L+
Sbjct: 421 ICAASFLSVYVAAIFWKRATRQGAIAGMVSGAIVSLFWLLF 461
>gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgidus]
>gi|7442768|pir||E69383 pantothenate permease (panF-1)
homolog - Archaeoglobus fulgidus
>gi|2649519|gb|AAB90171.1| (AE001029) pantothenate
permease (panF-1) [Archaeoglobus fulgidus]
Length = 491
Score = 165 bits (413), Expect = 1e-39
Identities = 114/490 (23%), Positives = 234/490 (47%), Gaps = 35/490 (7%)
Query: 21 LILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVT 80
L + +L+G Y ++T+ D+++ G+ + + V+ S ++ S+ LG G + +G
Sbjct: 11 LAVVLLIGIYEYRKTRGLLDYYLAGKKLGTLVVSFSFFATYFSTAAFLGGGGTGFLLGFQ 70
Query: 81 AVWAAV---GYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASII 137
W+A +++ + ++ + +++ ++ + A+T+P+ F R S+I+ A+++
Sbjct: 71 --WSAFLTFFHVLFAILAWMVIAPPMKRIADEYGALTIPELFRKRAGVFSQIV---AAVV 125
Query: 138 IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAV 197
II F Y+ + + L L + T L+I+ ++++VY +GGF AV D+I+ V
Sbjct: 126 IIFFFELYMVSIYKGAGNLLQVMLSMDYTTGLVITAVIVMVYTAIGGFRAVVMTDLIQGV 185
Query: 198 IMIIGLVVLPVIAVAKVGGTEEVLKVLHALD-------------PKLINPWAFGAGVVIG 244
I++IG V L + + +GG ++ L K+ P AG+++
Sbjct: 186 IVLIGGVALFLTLIYSLGGFSSAIEALSNAKIFGEMVGKALFEIGKVGPPPIVKAGMIVP 245
Query: 245 FL-----GIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAI 299
F+ I P ++VR+++ D + ++ + A +G G +
Sbjct: 246 FVLSLTFAISVAQLASPQLVVRFVAARDSRVIANGMILTPLIIGIFAICVFSIGPFGWLV 305
Query: 300 VP----DVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVV 355
+P DV+Q K+ +++ P+++ + FP + +L+ I AA +ST +S + +VA+ V
Sbjct: 306 IPKYTDDVTQFL-KDVDLVVPFIAMKLFPAGINALLLTAIIAAAMSTINSLIHLVATAFV 364
Query: 356 KDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASF 415
+DL Q V KI+E+TAL ++R V + + I A +I V ++ + ++F
Sbjct: 365 RDLVQNV----KKIEERTALNLTRFAVFIFATIPVIFAINPMGVIVEIVGVSFSVITSAF 420
Query: 416 GPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVS 475
LI LY + + A M+ + +++W Y + +Y +VP + S+ S
Sbjct: 421 LVPLIACLYSEKPNSAAISASMVAAVLASVLWYFYYYKVYWIYPVVPGLLVSIAVFAAFS 480
Query: 476 MITKPPENVE 485
+ P E
Sbjct: 481 LAFPQPSKAE 490
>gb|AAF45263.1| (AF230602) proline permease [Escherichia coli]
>gi|7288753|gb|AAF45265.1| (AF230604) proline permease
[Escherichia coli] >gi|7288757|gb|AAF45267.1| (AF230606)
proline permease [Escherichia coli]
>gi|7288765|gb|AAF45271.1| (AF230610) proline permease
[Escherichia coli] >gi|7288769|gb|AAF45273.1| (AF230612)
proline permease [Escherichia coli]
>gi|7288771|gb|AAF45274.1| (AF230613) proline permease
[Escherichia coli] >gi|7288773|gb|AAF45275.1| (AF230614)
proline permease [Escherichia coli]
>gi|7288775|gb|AAF45276.1| (AF230615) proline permease
[Escherichia coli] >gi|7288777|gb|AAF45277.1| (AF230616)
proline permease [Escherichia coli]
>gi|7288779|gb|AAF45278.1| (AF230617) proline permease
[Escherichia coli] >gi|7288781|gb|AAF45279.1| (AF230618)
proline permease [Escherichia coli]
>gi|7288785|gb|AAF45281.1| (AF230620) proline permease
[Escherichia coli] >gi|7288787|gb|AAF45282.1| (AF230621)
proline permease [Escherichia coli]
>gi|7288791|gb|AAF45284.1| (AF230623) proline permease
[Escherichia coli] >gi|7288797|gb|AAF45287.1| (AF230626)
proline permease [Escherichia coli]
>gi|7288799|gb|AAF45288.1| (AF230627) proline permease
[Escherichia coli] >gi|7288801|gb|AAF45289.1| (AF230628)
proline permease [Escherichia coli]
>gi|7288803|gb|AAF45290.1| (AF230629) proline permease
[Escherichia coli] >gi|7288805|gb|AAF45291.1| (AF230630)
proline permease [Escherichia coli]
>gi|7288807|gb|AAF45292.1| (AF230631) proline permease
[Escherichia coli] >gi|7288809|gb|AAF45293.1| (AF230632)
proline permease [Escherichia coli]
>gi|7288811|gb|AAF45294.1| (AF230633) proline permease
[Escherichia coli] >gi|7288813|gb|AAF45295.1| (AF230634)
proline permease [Escherichia coli]
>gi|7288815|gb|AAF45296.1| (AF230635) proline permease
[Escherichia coli]
Length = 232
Score = 160 bits (401), Expect = 3e-38
Identities = 82/230 (35%), Positives = 133/230 (57%), Gaps = 2/230 (0%)
Query: 39 EDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVY 98
+D+ +GGR++ ALSA +S S WL++GL G + G++ W A+G + +
Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61
Query: 99 MGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTL 157
+ RLR +E NA+T+PDYF RF D S+ILRI ++++I++F T Y + AGA+
Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121
Query: 158 STALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGT 217
+ G+S TAL I+Y +GGF+AV++ D ++A +MI L++ PVI + VGG
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181
Query: 218 EEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFGSPGQPHIIVRYMSID 266
+ L+V+ + ++ +I +G G G GQPHI+ R+M+ D
Sbjct: 182 GDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAAD 231
>gb|AAF45280.1| (AF230619) proline permease [Escherichia coli]
Length = 232
Score = 160 bits (401), Expect = 3e-38
Identities = 82/230 (35%), Positives = 133/230 (57%), Gaps = 2/230 (0%)
Query: 39 EDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVY 98
+D+ +GGR++ ALSA +S S WL++GL G + G++ W A+G + +
Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61
Query: 99 MGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTL 157
+ RLR +E NA+T+PDYF RF D S+ILRI ++++I++F T Y + AGA+
Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121
Query: 158 STALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGT 217
+ G+S TAL I+Y +GGF+AV++ D ++A +MI L++ PVI + VGG
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181
Query: 218 EEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFGSPGQPHIIVRYMSID 266
+ L+V+ + ++ +I +G G G GQPHI+ R+M+ D
Sbjct: 182 GDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAAD 231
>gb|AAF45283.1| (AF230622) proline permease [Escherichia coli]
Length = 232
Score = 160 bits (401), Expect = 3e-38
Identities = 82/230 (35%), Positives = 133/230 (57%), Gaps = 2/230 (0%)
Query: 39 EDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVY 98
+D+ +GGR++ ALSA +S S WL++GL G + G++ W A+G + +
Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61
Query: 99 MGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTL 157
+ RLR +E NA+T+PDYF RF D S+ILRI ++++I++F T Y + AGA+
Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121
Query: 158 STALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGT 217
+ G+S TAL I+Y +GGF+AV++ D ++A +MI L++ PVI + VGG
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181
Query: 218 EEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFGSPGQPHIIVRYMSID 266
+ L+V+ + ++ +I +G G G GQPHI+ R+M+ D
Sbjct: 182 GDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAAD 231
>gb|AAF45285.1| (AF230624) proline permease [Escherichia coli]
Length = 232
Score = 160 bits (401), Expect = 3e-38
Identities = 82/230 (35%), Positives = 133/230 (57%), Gaps = 2/230 (0%)
Query: 39 EDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVY 98
+D+ +GGR++ ALSA +S S WL++GL G + G++ W A+G + +
Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61
Query: 99 MGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTL 157
+ RLR +E NA+T+PDYF RF D S+ILRI ++++I++F T Y + AGA+
Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121
Query: 158 STALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGT 217
+ G+S TAL I+Y +GGF+AV++ D ++A +MI L++ PVI + VGG
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181
Query: 218 EEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFGSPGQPHIIVRYMSID 266
+ L+V+ + ++ +I +G G G GQPHI+ R+M+ D
Sbjct: 182 GDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGMGYFGQPHILARFMAAD 231
>gb|AAF45264.1| (AF230603) proline permease [Escherichia coli]
>gi|7288755|gb|AAF45266.1| (AF230605) proline permease
[Escherichia coli] >gi|7288759|gb|AAF45268.1| (AF230607)
proline permease [Escherichia coli]
>gi|7288761|gb|AAF45269.1| (AF230608) proline permease
[Escherichia coli] >gi|7288763|gb|AAF45270.1| (AF230609)
proline permease [Escherichia coli]
>gi|7288767|gb|AAF45272.1| (AF230611) proline permease
[Escherichia coli]
Length = 232
Score = 158 bits (396), Expect = 1e-37
Identities = 81/228 (35%), Positives = 132/228 (57%), Gaps = 2/228 (0%)
Query: 39 EDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVY 98
+D+ +GGR++ ALSA +S S WL++GL G + G++ W A+G + +
Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61
Query: 99 MGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTL 157
+ RLR +E NA+T+PDYF RF D S+ILRI ++++I++F T Y + AGA+
Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121
Query: 158 STALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGT 217
+ G+S TAL I+Y +GGF+AV++ D ++A +MI L++ PVI + VGG
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181
Query: 218 EEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFGSPGQPHIIVRYMS 264
+ L+V+ + ++ +I +G G G GQPHI+ R+M+
Sbjct: 182 GDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMA 229
>gb|AAF45286.1| (AF230625) proline permease [Escherichia coli]
Length = 232
Score = 157 bits (392), Expect = 3e-37
Identities = 80/230 (34%), Positives = 132/230 (56%), Gaps = 2/230 (0%)
Query: 39 EDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVY 98
+D+ +GGR++ ALS +S S WL++GL G + G++ W A+G + +
Sbjct: 2 DDYILGGRSLGPFVTALSVGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61
Query: 99 MGIRLRKFSE-RFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTL 157
+ RLR +E NA+T+P+YF RF D S+ILRI ++++I++F T Y + AGA+
Sbjct: 62 VAGRLRVHTEYNNNALTLPNYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121
Query: 158 STALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGT 217
+ G+S TAL I+Y +GGF+AV++ D ++A +MI L++ PVI + VGG
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181
Query: 218 EEVLKVLHALDPKLINPW-AFGAGVVIGFLGIGFGSPGQPHIIVRYMSID 266
+ L+V+ + ++ +I +G G G GQPHI+ R+M+ D
Sbjct: 182 GDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAAD 231
>pir||E70201 pantothenate permease (panF) homolog - Lyme disease spirochete
>gi|2688763|gb|AAC67168.1| (AE001180) pantothenate
permease (panF) [Borrelia burgdorferi]
Length = 444
Score = 157 bits (392), Expect = 3e-37
Identities = 116/450 (25%), Positives = 208/450 (45%), Gaps = 18/450 (4%)
Query: 41 FFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMG 100
+F+ R ++ I +AL SS S+ + YK G++ + A I + F+ +G
Sbjct: 6 YFLANRNINFIVMALLFSSSYISASSFISGPSAVYKYGLSFILLATIQIPTTLIVFIIVG 65
Query: 101 IRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTA 160
RL + S++ NAI + DY R+ S L + + ++I F + AQ GAK +
Sbjct: 66 QRLNRESKKINAINIIDYIRHRYE--SDFLALMSGFVLIFFSMFLISAQLIGGAKLIEVF 123
Query: 161 LGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEV 220
GI L ++ +Y+ GGF AVAY D+I+ +M++ V+L + GG +
Sbjct: 124 WGIDYVVGLTFFAFLVFIYVFFGGFKAVAYTDLIQGFLMLVSSVILFSKMLDLGGGINNL 183
Query: 221 LK-VLHALDPKLINPWAFGAG---VVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTV 276
K +LD L+ P ++ ++ IG G GQP II +++ D N ++ S
Sbjct: 184 FKTATSSLDKSLLLPSNADLKPQYIISFWILIGIGILGQPQIINNFIAFKDENAIKFSLP 243
Query: 277 VGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIF 336
+ TF L +G + PD+S + + ++ + P + G+
Sbjct: 244 ISTFIISFLIVLMHLIGFFAIILFPDLSP-----NDKVVLNVALKVLNPFSCFMFFIGLL 298
Query: 337 AAILSTADSQLLVVASTVVKD--LYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAY 394
+AI+ST DS LL++ S ++K +Y+E +K+ KI + IS + +++ I +
Sbjct: 299 SAIMSTVDSNLLLITSVLIKSIFIYKEDLKEDVKIGR--IIMISNIFFILI---ILIFSL 353
Query: 395 VAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPI 454
+ +F+ +FA+G L SF P ++ LY +K A M +G I + + I
Sbjct: 354 FPPNFLFFINIFAFGALEVSFFPIIVFGLYLNFVSKIAAFASMFLGLIFYLSILFFGLNI 413
Query: 455 TGLYELVPAFIFSLIATIIVSMITKPPENV 484
+ + P+F S+ ++V+ K V
Sbjct: 414 WFFHPVFPSFFVSIFTFLVVNFFCKKNSKV 443
>gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus]
>gi|7442766|pir||G69251 proline permease (putP-1)
homolog - Archaeoglobus fulgidus
>gi|2650635|gb|AAB91210.1| (AE001105) proline permease
(putP-1) [Archaeoglobus fulgidus]
Length = 491
Score = 154 bits (385), Expect = 2e-36
Identities = 107/479 (22%), Positives = 219/479 (45%), Gaps = 24/479 (5%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
+ L F+ TL L GF+A ++ K+ E ++ + A++ S S++ +G
Sbjct: 9 IVLAYFVVTLAL----GFFAARKIKTAEHYYGARKLFGMFVTAVAVFSGIASAFTFIGGP 64
Query: 72 GMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILR 131
G+ Y MG T W +++ + +G R++ +E T+PD ARF+ S +R
Sbjct: 65 GLVYPMGGTVNWVIWTPVISMPLIWYLLGKRIKLITEARPVATLPDLTAARFK--SDAVR 122
Query: 132 IAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYN 191
++ +I + +Y+ L+ LG + ++ I +I++Y GG +A
Sbjct: 123 FLTAVALIFGIITYLAGNVMGAGLVLTDMLGTPLELSIAIVFGIIMLYTAFGGMVASILT 182
Query: 192 DVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFG---AGVVIGFLGI 248
D + ++M++ ++ V + GG E + + +P+ I+P G G++ + +
Sbjct: 183 DFFQGLVMMVAAIIFVVFILIMTGGVENLFATIAESNPRHIDPIGVGPIWLGIMGWWWAL 242
Query: 249 GFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTF-WNVV-LAWGAIFVGLAG-RAIVPDVSQ 305
GS QPH + ++ ++ D L+ +V T W + L W F G A ++ +++
Sbjct: 243 NIGSSVQPHAVTKFFALKDYRDLKWGALVTTIAWTLACLMW--FFGGYASVWVVIKGLAE 300
Query: 306 LPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKK 365
P ++ + I+ ++ P +L ++ G+ AAI+ST + + + VV+D+ +
Sbjct: 301 APARSDQAIFGVIA--QMPVVLKAVIYAGVLAAIMSTVSGFISMGTAAVVRDIPTAI--- 355
Query: 366 GTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYW 425
G + ++ + RV +++ +AA+ Y ++ V G + P L++ L W
Sbjct: 356 GKSLSQRGQILWGRVVTVILTVVAALFGYYGGYVVGILVTLGLGYFASMLFPLLVIGLNW 415
Query: 426 KGTTKWGVLAGMIVGTITTIVWKLYLKPIT-----GLYELVPAFIFSLIATIIVSMITK 479
K TK + + + + +Y K ++ GL F +I ++VS+ITK
Sbjct: 416 KRATKEAAIITTALTVAMNLGFLVYEKVLSMSLPYGLPGYGVTFAVGIITMVLVSLITK 474
>sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK INTERGENIC REGION
>gi|7442759|pir||S39686 Na+-dependent symport homolog
ywcA - Bacillus subtilis >gi|580869|emb|CAA51587.1|
(X73124) ipa-31r [Bacillus subtilis]
>gi|2636359|emb|CAB15850.1| (Z99123) alternate gene
name: ipa-31r~similar to Na+-dependent symport [Bacillus
subtilis]
Length = 516
Score = 146 bits (364), Expect = 7e-34
Identities = 106/426 (24%), Positives = 198/426 (45%), Gaps = 16/426 (3%)
Query: 30 YAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYI 89
+ KRTK+ +F+ G + + L+ S+ LG++GM G + ++G++
Sbjct: 25 FCAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFYSIGFL 84
Query: 90 VAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQ 149
VA + + LR + T+ D ARF++ K +R A++ I T Y+ AQ
Sbjct: 85 VAYLVVLYIVAEPLRNLGK----YTMADMIAARFKE--KKIRGVAALNTIAISTFYMIAQ 138
Query: 150 FNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVI 209
+ LG+ A++I +++ +Y++ GG IA ++ +I+AV+++ G +V+ +I
Sbjct: 139 LVGAGALIKLLLGLDYTAAVLIVGVLMTIYVVFGGMIATSWVQIIKAVLLMAGTLVISII 198
Query: 210 AVAKVGGT----EEVLKVLHALDPKLINP---WAFGAGVVIGFLGIGFGSPGQPHIIVRY 262
+K G + E +K L +NP + + L + G+ G PHI++R+
Sbjct: 199 VFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLALVLGTAGLPHILIRF 258
Query: 263 MSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVP-DVSQLPGKNAEMIYPYLSAQ 321
++ D R S V T+ V +F+G A V D + M P L+
Sbjct: 259 YTVKDAKTARTSVVSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQAGNMAAPLLAKA 318
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
L+ + FA IL+ +L AS D+Y ++I+KG + EK + +R
Sbjct: 319 LGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKG-EATEKEQMKAARWA 377
Query: 382 VLVVGFLAAILAYVAKDI-IFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVG 440
+ V L+ +LA A+ + + + V A+ ++ P ++ +++WK G L G + G
Sbjct: 378 SVAVSVLSILLAIFAQSLNVAFLVALAFAVAASANLPLIVFTVFWKRFNASGALWGSLTG 437
Query: 441 TITTIV 446
I+ +V
Sbjct: 438 LISALV 443
>gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus]
>gi|7483927|pir||E69402 proline permease (putP-3)
homolog - Archaeoglobus fulgidus
>gi|2649354|gb|AAB90016.1| (AE001019) proline permease
(putP-3) [Archaeoglobus fulgidus]
Length = 479
Score = 141 bits (352), Expect = 2e-32
Identities = 117/488 (23%), Positives = 224/488 (44%), Gaps = 60/488 (12%)
Query: 40 DFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAV-GYIVAEMFQFVY 98
DF + T L + S S ++G++G+A+ G VW + G A F +
Sbjct: 3 DFVAASGQLGFWTYCLLMIGSVFSGMTLIGVAGLAFTTGYANVWERIIGPPFAIAFGTIL 62
Query: 99 MGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLS 158
+G +L ++ +T+ DY R+ D KI+RI A +I + Y+ Q+ A
Sbjct: 63 IGYKLFNLKDKNGILTIQDYLAFRY-DDPKIIRILAGLISAVTCFVYLIGQYTAIGVVSY 121
Query: 159 TALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTE 218
LGI + +I+ ++++ Y++ GG + A+ +++++M++G+ V +A VGG E
Sbjct: 122 VVLGIPYWLGAVIAAVIVVAYVMSGGMFSTAWTTFLQSILMLLGIYVTVPFIIAWVGGFE 181
Query: 219 EVLKVLHALDPKLIN-----------------PWAFGAGVVIGF--------LGIGFGSP 253
+ + L A+ P++ N P+A + + G+ + + G
Sbjct: 182 AMNQALAAM-PEIQNATRGVAENFMFAKYLSKPFAPASVPLAGWVYNLTLFGITVPLGLM 240
Query: 254 GQPHIIVRYMSIDDPNKLRVSTVVGTFWN----VVLAWGAIFV-GLAGRAI--------- 299
PHI+ N L + T W V+ + AIF+ LAG A
Sbjct: 241 VAPHIV--------NNMLTFRKIEYTRWGPLVMYVIGFSAIFLTALAGMAARVAWAKGMI 292
Query: 300 -VPDVS--QLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVK 356
+P ++ + K ++M YP ++++ P L+ +L+ I A ++ST D +L A+ +
Sbjct: 293 DIPSLTLGSIEVKWSDMAYPTIASKALPYWLFVLLLPTILAGVMSTTDRLILTAANNISY 352
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFG 416
D+ + + G + E ++ + V ++GF + ++A + ++ WF+ A + F
Sbjct: 353 DVLRNAL--GKNLSENALKKVNMLVVPLIGFGSLLIALFPQQLLAWFIWAALSLMTNCFF 410
Query: 417 PTLILSLYWKGTTKWGVLAGMIVGTITTI-VWKLYLKP--ITGL--YELVPAFIFSLIAT 471
++L LYW TK MI G + T+ + +Y K I G+ Y ++P F+ S +
Sbjct: 411 FPIMLGLYWDRMTKNAARLSMIAGFVVTLATFAIYGKTIYIAGIPAYSVLPGFVASFVLA 470
Query: 472 IIVSMITK 479
+ VS++ K
Sbjct: 471 VGVSLLEK 478
>sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS INTERGENIC REGION (F549)
>gi|7442761|pir||B65215 hypothetical 59.2 kD protein in
soxR-acs intergenic region - Escherichia coli (strain
K-12) >gi|396402|gb|AAC43161.1| (U00006) similar to
Salmonella proline permease [Escherichia coli]
>gi|1790503|gb|AAC77037.1| (AE000480) putative transport
protein [Escherichia coli K12]
Length = 549
Score = 141 bits (351), Expect = 2e-32
Identities = 110/450 (24%), Positives = 208/450 (45%), Gaps = 26/450 (5%)
Query: 13 ALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSG 72
A++ FL ++ + + ++A KR +S D++ G + L+ S+ LG+S
Sbjct: 35 AIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISA 94
Query: 73 MAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
+ + G + ++G++V + RLR R+ V A +R +RI
Sbjct: 95 LVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLG-RYTFADV-----ASYRLKQGPIRI 148
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++ ++ + Y+ AQ K + G++ A+++ +++++Y++ GG +A +
Sbjct: 149 LSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQ 208
Query: 193 VIRAVIMIIGLVVLPVIAVAKVG-GTEEVLKVLHALDPKLINPWAFG-------AGVVIG 244
+I+AV+++ G + + + VG + A+ PK ++ G + + +G
Sbjct: 209 IIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLG 268
Query: 245 FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGT-------FWNVVLAWGAIFVGLAGR 297
LG+ FG+ G PHI++R+ ++ D + R S T ++ +GAI + A
Sbjct: 269 -LGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANP 327
Query: 298 AIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKD 357
L G N M +L+ + G + FA IL+ L AS V D
Sbjct: 328 EYKDAAGHLIGGN-NMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHD 386
Query: 358 LYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFG- 416
LY V KKG E+ L +S++TVL++G +A IL + ++ F++ + AS
Sbjct: 387 LYANVFKKGA--TEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNF 444
Query: 417 PTLILSLYWKGTTKWGVLAGMIVGTITTIV 446
P ++LS+YW T G + G +G IT +V
Sbjct: 445 PIILLSMYWSKLTTRGAMMGGWLGLITAVV 474
>emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas putida]
>gi|3253206|gb|AAC24338.1| (AF029714) PhaJ [Pseudomonas
putida]
Length = 520
Score = 140 bits (350), Expect = 3e-32
Identities = 119/462 (25%), Positives = 209/462 (44%), Gaps = 43/462 (9%)
Query: 10 NPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
N A+ F+ + +LV +A RT+S DF+ G + + L+ S+ LG
Sbjct: 2 NWTAISMFMVFVCFTLLVTRWAALRTRSASDFYTAGGGLTGMQNGLAIAGDMISAASFLG 61
Query: 70 LS---------GMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFE 120
+S G+ Y +GV A W + +++AE RLR + T D
Sbjct: 62 ISAMMFMNGYDGLLYALGVLAGWPIILFLIAE---------RLRNLGK----YTFADVVS 108
Query: 121 ARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYM 180
R T L A +++ + Y+ AQ K + GIS A+M+ ++++ Y+
Sbjct: 109 YRLAQTPVRLTSAFGTLVVALM--YLVAQMVGAGKLIELLFGISYLYAVMLVGVLMVAYV 166
Query: 181 ILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL----KVLHALDPKLINPWA 236
GG +A + +I+AV+++ G + + + G + E + +HA ++ P
Sbjct: 167 TFGGMLATTWVQIIKAVMLLSGTSFMAFMVLKHFGFSTEAMFASAVAVHAKGQAIMAPGG 226
Query: 237 FGAGVVIGF---LGIGFGSPGQPHIIVRYMSIDDPNKLRVST-----VVGTFW--NVVLA 286
+ V LG+ FG+ G PHI++R+ ++ D + R S +G F+ +V+
Sbjct: 227 LLSNPVDAISLGLGMMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYLLLIVIG 286
Query: 287 WGAIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQ 346
+GAI V + D + MI +L+ + G + FA IL+
Sbjct: 287 FGAI-VMVGTEPSYRDATGAIIGGGNMIAVHLAQAVGGNLFLGFISAVAFATILAVVAGL 345
Query: 347 LLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILA--YVAKDIIFWFV 404
L AS V DLY VI++G K E+ + +SR+ L++G LA +L + +++I F
Sbjct: 346 ALSGASAVSHDLYACVIRQG-KATEQEEMRVSRIATLLIGLLAVLLGLMFESQNIAFLSG 404
Query: 405 LFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIV 446
L +F P L+LS++WKG T G + G + G + ++
Sbjct: 405 LVLAVAASVNF-PVLLLSMFWKGLTTRGAVCGSMAGLASAVL 445
>pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii
>gi|3257459|dbj|BAA30142.1| (AP000004) 491aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 491
Score = 139 bits (348), Expect = 5e-32
Identities = 135/485 (27%), Positives = 235/485 (47%), Gaps = 32/485 (6%)
Query: 13 ALVAFLFTLILPILVGFYA-MKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
AL+ L + L ++VG A +KR + E + V GR + I + + S++ LG
Sbjct: 16 ALIIVLGWVFLSLIVGVMAGIKRKFTLEGYLVSGRTLGLIFLYVLMAGEIYSAYAFLGTG 75
Query: 72 GMAYKMGVTAVWAAVGYIVAEMFQFVYMGIR-LRKFSERFNAITVPDYFEARFRDTSKIL 130
G AY G+ ++A +GY A + F Y R + K + F +T DYF+ R+ SK L
Sbjct: 76 GWAYSYGMPIMYA-IGY-GALAYSFGYFYARYVWKAGKAFGCVTQADYFQVRYN--SKAL 131
Query: 131 RIAASIIIIIFLTSYVGAQFNA-GAKTLSTALG-ISIFTALMISVLMIIVYMILGGFIAV 188
+ ++I IIF Y+ Q G +LG I+ ++I ++++++Y+ G +
Sbjct: 132 AVLVALIGIIFNIPYLQLQLQGLGYIVHVGSLGSITPKAGIVIGMIIMMIYVYTSGLRGI 191
Query: 189 AYNDVIRAVIM-IIGLVVLPVIAVAKVGGTEEVLKVLHALDPK--LINPWAFGAGVVIGF 245
++ ++++A +M I+ VVL I + GG E+ K L P +++P + V
Sbjct: 192 SWTNLLQATLMFIVAWVVLFTIPFKQFGGIGELFKTLAQTKPDHLILHPPLGISWYVSTL 251
Query: 246 LGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNV----VLAWGAIFVGLAGRAIVP 301
+ G G P + D L+ + V+ +++ V+ G L + P
Sbjct: 252 ILSGLGFFMYPQLYPSIYGARDLKTLKRNYVLLPLYSIFMIPVILAGFTVAALGIKLSAP 311
Query: 302 DVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQE 361
D + L K E+ YP + G++ FAA STA + LL +A + K+LY
Sbjct: 312 DEAVL--KAVEITYPSW--------VLGVVGAAGFAAAASTASAILLSLAGLLSKNLY-- 359
Query: 362 VIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLIL 421
I K T D++ L +SR++V+++G LA LA + + +L A+ G+ F P +
Sbjct: 360 AIAKPTASDKELVL-VSRISVILLGLLAMGLALYSPGRLVSLLLLAYAGMTQMF-PGAVF 417
Query: 422 SLYWKGTTKWGVLAGMIVGTITTIVWKLYLK--PITGLYELVPAFIFSLIATIIVSMITK 479
L+WK K+ G+I G IT +L LK P+ G++ + + ++I T+IV+ +TK
Sbjct: 418 GLFWKRMNKYATGTGIIAGLITVAYLRLVLKKNPL-GIHFGLWGLLVNIIVTLIVAYLTK 476
Query: 480 PPENV 484
P E +
Sbjct: 477 PEEEL 481
>pir||F83241 probable sodium:solute symporter PA3234 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949356|gb|AAG06622.1|AE004746_6 (AE004746) probable
sodium:solute symporter [Pseudomonas aeruginosa]
Length = 551
Score = 139 bits (346), Expect = 9e-32
Identities = 115/489 (23%), Positives = 215/489 (43%), Gaps = 35/489 (7%)
Query: 10 NPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
N A+V F+ + + + ++A KR +S D++ G + L+ S+ LG
Sbjct: 33 NVSAIVMFVAFVGATLCITYWASKRNRSAADYYAAGGRITGFQNGLAIAGDYMSAASFLG 92
Query: 70 LSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTS-K 128
+S + + G + ++G++V + RLR + T D R + +
Sbjct: 93 ISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGK----YTFADVASYRLKQKQIR 148
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
L S++++ F Y+ AQ K + G++ A+++ +++++Y++ GG +A
Sbjct: 149 TLSACGSLVVVAF---YLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVLYVLFGGMLAT 205
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGT-----EEVLKVLHALDPKLINPWAFGAGVVI 243
+ +I+AV+++ G + ++ + V E +KV H +++P +
Sbjct: 206 TWVQIIKAVLLLSGASFMAIMVLKHVNFDVSTLFSEAIKV-HPKGEAIMSPGGLVKDPIS 264
Query: 244 GF---LGIGFGSPGQPHIIVRYMSIDDPNKLRVST-----VVGTFW--NVVLAWGAIFVG 293
F + FG+ G PHI++R+ ++ D + R S +G F+ ++ +GAI +
Sbjct: 265 AFSLGFALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLV 324
Query: 294 LAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVAST 353
L G N M +L+ + G + FA IL+ L AS
Sbjct: 325 STNPDFKDATGALIGGN-NMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLAGASA 383
Query: 354 VVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYV-AKDIIFWFVLFAWGGLG 412
V DLY V KG K +EK L +S++T + +G +A +L + K I + V A+
Sbjct: 384 VSHDLYASVF-KGGKANEKDELRVSKMTTVALGVVAIVLGILFEKQNIAFMVGLAFSIAA 442
Query: 413 ASFGPTLILSLYWKGTTKWGVLAGMIVGTITTI--------VWKLYLKPITGLYELVPAF 464
+ P L+LS+YWK T G + G +G IT + +W L +Y
Sbjct: 443 SCNFPVLLLSMYWKKLTTRGAMIGGWMGLITAVGLMVLGPTIWVQILGHEKAIYPYEYPA 502
Query: 465 IFSLIATII 473
+FS+I +
Sbjct: 503 LFSMIVAFV 511
>pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107405|gb|AAF85050.1|AE004037_11 (AE004037)
solute:Na+ symporter [Xylella fastidiosa]
Length = 577
Score = 133 bits (332), Expect = 4e-30
Identities = 129/479 (26%), Positives = 216/479 (44%), Gaps = 58/479 (12%)
Query: 10 NPVALVAFLFTLILPILVGFYAMKRTKSEEDF---------FVGGRAMDKITVALSAVSS 60
N V + F+ +++ + + +A KRT+S DF F G AM ++ +A
Sbjct: 35 NWVVISIFVVFVLITLWITKWAAKRTRSSADFYTAGGTITGFQNGLAMAGDYMSAAAFLG 94
Query: 61 GRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFE 120
S+ ++ G GM Y +G W + ++VAE RLR + T D
Sbjct: 95 ITSAVMISGYDGMLYAIGSLVGWPILVFLVAE---------RLRNLGK----YTFADVVA 141
Query: 121 ARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYM 180
RF L +AS ++++ L S V AGA + G+ + A+++ +++VY+
Sbjct: 142 YRFAAVPVRLFTSASTLVVV-LCSLVAQMVGAGA-LIKLLFGLDYWVAVILVGGLMMVYV 199
Query: 181 ILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL------------------- 221
+ GG A + +I+AV+++ L + V+ + + G E L
Sbjct: 200 MFGGMAATTWVQIIKAVLLLTCLTFMAVMIMWRFGFNFEGLFASAVGVKTQIAMAGGKSG 259
Query: 222 KVLHALDPKLINPWAFGAGVVIGF-LGIG--FGSPGQPHIIVRYMSIDDPNKLRVSTVVG 278
+ AL ++ P +F + LGI FG+ G PHI++R+ ++ D ++R S +
Sbjct: 260 EEAKALGLSIMAPGSFIKDPISAISLGIALVFGNVGLPHILMRFFAVPDAREVRHSVLWA 319
Query: 279 TFW-------NVVLAWGAIFVGLAGR--AIVPDVSQLPGKNAEMIYPYLSAQYFP-PILY 328
W ++ +GAI L A + + G+ A + L A+ +
Sbjct: 320 ITWIGYCYILMFIVGFGAIVFVLTNPQYADIATGTIRGGQGAANMAAVLVAKVVGGDVFM 379
Query: 329 GILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFL 388
G + FA IL+ A L AS V D+Y VIK+G K T L +SRVT V+G +
Sbjct: 380 GFVSAVAFATILAVAAGLALSGASAVSHDVYAMVIKQG-KPSSDTELLVSRVTTAVLGVV 438
Query: 389 AAILAYV-AKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIV 446
A +L V K + + V A+ ++ P LILSL WK T WG + G +G I+++V
Sbjct: 439 AVLLGIVFQKQNVAFMVSLAFAIAASANFPVLILSLLWKNCTTWGAVIGGFLGLISSLV 497
>pir||E70480 probable sodium/proline symporter ssf [similarity] - Aquifex
aeolicus >gi|2984319|gb|AAC07841.1| (AE000773)
Na(+):solute symporter (Ssf family) [Aquifex aeolicus]
Length = 487
Score = 131 bits (326), Expect = 2e-29
Identities = 118/466 (25%), Positives = 201/466 (42%), Gaps = 70/466 (15%)
Query: 86 VGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSY 145
+ YI+ +V + + + + +F TVPD+ R+ S R+ A II II +Y
Sbjct: 19 LAYIMGWTGGYVLLALLIAPYLRKFGKFTVPDFIAERYE--SNFARLVALIIAIIISFTY 76
Query: 146 VGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVV 205
+ Q + G+ + I +++II +LGG ++ + V + +++I ++
Sbjct: 77 MVGQVAGVGIIMGRLFGVPFEIGIAIGMIVIIATTVLGGMKSITWTQVAQYIVLITAYLL 136
Query: 206 -------------LPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIGFLGIGF-- 250
LP V L+ H + P I P+ +I FL + F
Sbjct: 137 PVSLLAMQWFGIPLPQFLYGNVLQWIVDLEKQHGISPHYIEPYV--KFNMIQFLALMFVL 194
Query: 251 --GSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGA-IFVGLAGRAIVPDV---- 303
G+ PH+++R+ + R S F+ +L A + A ++ DV
Sbjct: 195 MAGTAALPHVLMRFFTTPSVKDARWSAGWALFFIAILYLTAPAYAAFARYVVLKDVVGKP 254
Query: 304 -SQLPG---------------KNAEMIYPYLSAQYFPPIL---------------YGILI 332
QLP +N + I + Q I+ Y ++
Sbjct: 255 IDQLPAWAQKWAETGLFKVIDQNGDGIIQWAELQLHRDIVVLATPEIAGLSLLVGYFVMA 314
Query: 333 GGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAIL 392
GG+ AA LSTAD LLV+A+ V DLY ++I EK + + ++ V V G + +
Sbjct: 315 GGL-AAALSTADGLLLVIAAAVSNDLYAKMINPNA--PEKKIVMLGKIAVAVAGVIGGFV 371
Query: 393 AYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLK 452
A + I V +A+ ASF P L+L ++WK K G +AGM+ G + TI++ +YL
Sbjct: 372 AAMKIGFIVQIVAWAFSLATASFFPALVLGIFWKRLNKEGAIAGMVAGLLVTIIY-IYLN 430
Query: 453 PITGLYEL--------VPAFIFSLIATIIVSMITKPP-ENVEELMK 489
G L V + +LI + IV+M+T PP E V++L++
Sbjct: 431 KTQGFSILGIQHTASGVFGLLVNLIVSYIVTMMTPPPSERVQKLVE 476
>pir||T03475 transmembrane protein - Rhodobacter capsulatus
>gi|3128276|gb|AAC16128.1| (AF010496) transmembrane
protein DhlC homolog [Rhodobacter capsulatus]
Length = 578
Score = 130 bits (324), Expect = 3e-29
Identities = 115/474 (24%), Positives = 202/474 (42%), Gaps = 50/474 (10%)
Query: 10 NPVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
N A+ F F ++ + + +A RTKS DF+ G + L+ S+ LG
Sbjct: 39 NWTAIAMFGFFVVATLFITKWAAGRTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLG 98
Query: 70 LSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKI 129
+S G + ++G++V M RLR + T D F T
Sbjct: 99 ISAAVMLQGYDGLIYSIGFLVGWPILTFLMAERLRNLGK----FTFADVAAFPFAQTP-- 152
Query: 130 LRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVA 189
+R+ A++ ++ + Y+ AQ + + G+ A+++ ++++VY++ GG A
Sbjct: 153 VRVFAAMSTLVVVAFYLIAQMVGAGQLIKLLFGLEYLYAVIVVGILMMVYVLFGGMTATT 212
Query: 190 YNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVV------- 242
+ +I+A +++ G + ++ + G + L+ L A K+ A AG
Sbjct: 213 WVQIIKACLLLGGASFMALMVMVHYGFS---LESLFADSVKVKTDLALAAGKTPEEAAAA 269
Query: 243 -IGFLGIG-----------------FGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFW--- 281
I +G G FG+ G PHI++R+ ++ + R S + T W
Sbjct: 270 GISIMGPGTFVKDPISAISFGMALMFGTAGLPHILMRFFTVPSAKEARKSVMWATVWIGY 329
Query: 282 ----NVVLAWGAIFVGLAGRAIVP-----DVSQLPGKNAEMIYPYLSAQYFPPILYGILI 332
++ +GAI L +V ++ + G N I +L+ I G +
Sbjct: 330 FYMLTFIIGFGAIVYVLTNPGLVSYDAKGALTLVGGNNMAAI--HLAQAVGGNIFLGFIS 387
Query: 333 GGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAIL 392
FA IL+ L AS V DLY V K G K D + L +SR+T + +G +A +L
Sbjct: 388 AVAFATILAVVAGLTLSGASAVSHDLYSTVFKNG-KADSASELRVSRITTICLGIVAVVL 446
Query: 393 AYV-AKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTI 445
K I + V A+ ++ P L +SL WKG T G + G +G I+++
Sbjct: 447 GLAFEKQNIAFMVSLAFAIAASANFPVLFMSLLWKGMTTRGAVIGGSLGLISSV 500
>sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE SYMPORTER)
>gi|8886895|gb|AAF80602.1|AF255301_1 (AF255301)
Na+/galactose cotransporter SGLT [Vibrio
parahaemolyticus]
Length = 543
Score = 128 bits (319), Expect = 1e-28
Identities = 117/514 (22%), Positives = 225/514 (43%), Gaps = 58/514 (11%)
Query: 12 VALVAFLFTLILPILVGFYAMK----RTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLV 67
+ ++ F + + I VG + + KS ED+F+ G+++ V S +++ S+
Sbjct: 11 IDIMVFAIYVAIIIGVGLWVSRDKKGTQKSTEDYFLAGKSLPWWAVGASLIAANISAEQF 70
Query: 68 LGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTS 127
+G+SG Y +G+ A Y + +G T+P++ E RF
Sbjct: 71 IGMSGSGYSIGL----AIASYEWMSAITLIIVGKYFLPIFIEKGIYTIPEFVEKRFN--K 124
Query: 128 KILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIA 187
K+ I A I +++ + + G L T LGI + +++ L +VY I GG A
Sbjct: 125 KLKTILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYGGLSA 184
Query: 188 VAYNDVIRAVIMIIGLVVLPVIAVAKVGGTE---------------EVLKVLHALDPKLI 232
V + DVI+ +++G + +AV+ +GGT+ +L +P+ +
Sbjct: 185 VVWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFAGVSKMVDAAPGHFEMILDQSNPQYM 244
Query: 233 NPWAFGAGVVIGFLGI------GFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLA 286
N G V+IG L + GF +II R ++ ++ + V F +++
Sbjct: 245 N--LPGIAVLIGGLWVANLYYWGFNQ----YIIQRTLAAKSVSEAQKGIVFAAFLKLIVP 298
Query: 287 WGAIFVGLAGRAIVPD-----------VSQLP-GKNAEMIYPYLSAQYFPPILYGILIGG 334
+ + G+A I D + LP NA+ YP+L+ Q+ P + G++
Sbjct: 299 FLVVLPGIAAYVITSDPQLMASLGDIAATNLPSAANADKAYPWLT-QFLPVGVKGVVFAA 357
Query: 335 IFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAY 394
+ AAI+S+ S L A+ D+Y+E I + + + + R +V +A ++A
Sbjct: 358 LAAAIVSSLASMLNSTATIFTMDIYKEYISPDS--GDHKLVNVGRTAAVVALIIACLIAP 415
Query: 395 VAKDI--IFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLK 452
+ I F ++ G + +L L+WK TT G I+G + +I + L+LK
Sbjct: 416 MLGGIGQAFQYIQEYTGLVSPGILAVFLLGLFWKKTTS----KGAIIGVVASIPFALFLK 471
Query: 453 PITGLYELVPAFIFSLIATIIVSMITKPPENVEE 486
+ + +++L+ T++V T ++ +
Sbjct: 472 FMPLSMPFMDQMLYTLLFTMVVIAFTSLSTSIND 505
>pir||S52839 dhlC protein - Xanthobacter autotrophicus
>gi|763398|emb|CAA60038.1| (X86084) dhlC [Xanthobacter
autotrophicus]
Length = 516
Score = 128 bits (318), Expect = 2e-28
Identities = 114/474 (24%), Positives = 215/474 (45%), Gaps = 39/474 (8%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
+AL F+ L L + + ++A +RT++ DF+ + I + S+ LG S
Sbjct: 4 LALAIFVAILALTLAITWWAARRTRTASDFYTADGTLGPIQNGFALAGDWMSAAAFLGFS 63
Query: 72 GMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILR 131
G+A G+ A G +VA + + + +R + RF T+ D FR R
Sbjct: 64 GLAALYGMDGSLYAAGALVAFLAILMLVAEPIRN-TGRF---TLGDVIA--FRMQRPQAR 117
Query: 132 IAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYN 191
+AA + ++ +Y+ Q GA + LG+ ++++ L ++VY++ GG IA +
Sbjct: 118 LAAVLGTVVVSLAYLVPQMAGGAALIKLLLGVPYAISIVVVGLGMLVYVVFGGMIATTWV 177
Query: 192 DVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALD----PKLINPWAFGA----GVVI 243
+I+AV+++ VL + +A G + V A + K++ P + + +
Sbjct: 178 QIIKAVMLLSAAAVLVALLLAHFG--FDPFSVFAAAEDTYGAKILAPGNYLKHPLDQLSL 235
Query: 244 GFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIF-----VGLAGRA 298
G L FG+ G PH++ R+ ++ D R S V W + LA G+ F +GL
Sbjct: 236 G-LSFAFGTAGLPHVMTRFYTVPDAQTARRSAV----WLMFLA-GSFFLVTTLIGLGSAV 289
Query: 299 IV-PDVSQLPGKNAEMIYPYLSAQYF--------PPILYGILIGGIFAAILSTADSQLLV 349
+V D + K + P L AQ+ + +++ FA IL+ + L
Sbjct: 290 LVGQDAIRAADKGGNLALPLL-AQHLGGGPDSIGGQVFLAVVVAVAFATILAVVAALTLS 348
Query: 350 VASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI-IFWFVLFAW 408
+ + DLY V+ +G + E+ + ++R++ ++V A + +A+ I + V+ A
Sbjct: 349 TSGAIAHDLYVNVL-RGGHVSEQEQVKVARISTVIVSAFAILFGLLAQGINVAVLVILAI 407
Query: 409 GGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVP 462
++ P ++LSL+W+ GV+ GM+ G ++ + L G L P
Sbjct: 408 SVAASANFPVIVLSLFWQRFNTAGVVTGMVAGLVSAVALALTGPAFMGADALFP 461
>dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemolyticus]
Length = 530
Score = 127 bits (317), Expect = 2e-28
Identities = 113/486 (23%), Positives = 214/486 (43%), Gaps = 54/486 (11%)
Query: 36 KSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQ 95
KS ED+F+ G+++ V S +++ S+ +G+SG Y +G+ A Y
Sbjct: 26 KSTEDYFLAGKSLPWWAVGASLIAANISAEQFIGMSGSGYSIGL----AIASYEWMSAIT 81
Query: 96 FVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAK 155
+ +G T+P++ E RF K+ I A I +++ + + G
Sbjct: 82 LIIVGKYFLPIFIEKGIYTIPEFVEKRFN--KKLKTILAVFWISLYIFVNLTSVLYLGGL 139
Query: 156 TLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVG 215
L T LGI + +++ L +VY I GG AV + DVI+ +++G + +AV+ +G
Sbjct: 140 ALETILGIPLMYSILGLALFALVYSIYGGLSAVVWTDVIQVFFLVLGGFMTTYMAVSFIG 199
Query: 216 GTE---------------EVLKVLHALDPKLINPWAFGAGVVIGFLGI------GFGSPG 254
GT+ +L +P+ +N G V+IG L + GF
Sbjct: 200 GTDGWFAGVSKMVDAAPGHFEMILDQSNPQYMN--LPGIAVLIGGLWVANLYYWGFNQ-- 255
Query: 255 QPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD-----------V 303
+II R ++ ++ + V F +++ + + G+A I D
Sbjct: 256 --YIIQRTLAAKSVSEAQKGIVFAAFLKLIVPFLVVLPGIAAYVITSDPQLMASLGDIAA 313
Query: 304 SQLP-GKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEV 362
+ LP NA+ YP+L+ Q+ P + G++ + AAI+S+ S L A+ D+Y+E
Sbjct: 314 TNLPSAANADKAYPWLT-QFLPVGVKGVVFAALAAAIVSSLASMLNSTATIFTMDIYKEY 372
Query: 363 IKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI--IFWFVLFAWGGLGASFGPTLI 420
I + + + + R +V +A ++A + I F ++ G + +
Sbjct: 373 ISPDS--GDHKLVNVGRTAAVVALIIACLIAPMLGGIGQAFQYIQEYTGLVSPGILAVFL 430
Query: 421 LSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKP 480
L L+WK TT G I+G + +I + L+LK + + +++L+ T++V T
Sbjct: 431 LGLFWKKTTS----KGAIIGVVASIPFALFLKFMPLSMPFMDQMLYTLLFTMVVIAFTSL 486
Query: 481 PENVEE 486
++ +
Sbjct: 487 STSIND 492
>gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus]
>gi|7442764|pir||A69371 proline permease (putP-2)
homolog - Archaeoglobus fulgidus
>gi|2649629|gb|AAB90273.1| (AE001037) proline permease
(putP-2) [Archaeoglobus fulgidus]
Length = 531
Score = 125 bits (312), Expect = 8e-28
Identities = 136/526 (25%), Positives = 220/526 (40%), Gaps = 70/526 (13%)
Query: 11 PVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGL 70
PV + L+ L + I++G+Y+ +R KS D++V GR + + L+ S+ S +LGL
Sbjct: 7 PVIGITVLYFLAI-IIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASMLGL 65
Query: 71 SGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKIL 130
+ +G WA I + LRK++ A DY+ R+ D L
Sbjct: 66 PAYIFILGYPFWWAMSAIIAGMPIATLLTASALRKYAPTSFA----DYYADRYNDQR--L 119
Query: 131 RIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAY 190
R I+ +I Y+ A L + L++ +++++Y++ GG IA ++
Sbjct: 120 RWLVGIVTVIGAVLYITLSLVGMALFLLAVAKVPYIIGLIVGTIIVMLYVVWGGMIATSW 179
Query: 191 NDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN------PWAFGAGVVIG 244
N +A +M + V+ + V K+GG + + A +PK N P +G I
Sbjct: 180 NAAFQAFLMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNTPSDPEPPHLLSGTWIA 239
Query: 245 FLGIGF----GSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGL----AG 296
+G F G P+ +VR+ + D R S FW LA G ++ L A
Sbjct: 240 VIGWFFVWHYGFATMPYTVVRFFTTMDIKTARRS----IFW-CTLAAGIFYMALEIIGAA 294
Query: 297 RAIVPDVSQLPGK--NAEMIYPYLSAQY-----------------FPPILYGILIGGIFA 337
++ + + G+ NA I AQY P + GIL G A
Sbjct: 295 SKLMIETGPMGGEGANAVKILQSYMAQYGVGGWTDYSMIAAVEALQNPWVLGILCAGGLA 354
Query: 338 AILSTADSQLLVVASTVVKDLYQEVIK-KGTKIDEKTALTISRVTVLVVGFLAAI-LAYV 395
+STA ++VV + + +D ++K K K T I V L+VGFL AI +
Sbjct: 355 IAMSTAAGWVMVVNTLLTRDWGDMLLKSKFAKEKPVTLARIISVIFLIVGFLVAINPPGL 414
Query: 396 AKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPIT 455
D+ W A+ + ++ GP L+L L+WK T+ + IV T + L K +
Sbjct: 415 VLDLSGW----AFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTPLHLYAWLKAKLVL 470
Query: 456 GLYEL-------------------VPAFIFSLIATIIVSMITKPPE 482
G + V A + IIVS+ITKP E
Sbjct: 471 GHHAFFFLNDVLFGNAKALITPHQVWAIPVGFLLFIIVSLITKPVE 516
>sp|P11170|SL51_RABIT SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE COTRANSPORTER 1)
(HIGH AFFINITY SODIUM-GLUCOSE COTRANSPORTER)
>gi|2119799|pir||A37226 glucose transport protein -
rabbit >gi|1641|emb|CAA29727.1| (X06419) put.
Na(+)/glucose co-transporter (AA 1-662) [Oryctolagus
cuniculus] >gi|1717|emb|CAA39040.1| (X55355) cortical
sodium-D-glucose cotransporter [Oryctolagus cuniculus]
>gi|225827|prf||1314254A Na/glucose co-transporter
[Oryctolagus cuniculus]
Length = 662
Score = 121 bits (301), Expect = 2e-26
Identities = 123/552 (22%), Positives = 241/552 (43%), Gaps = 87/552 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
+YE ++N + + ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 19 SYERIRNAADISVIVIYFLVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ +V + FV + IR +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAASGIATGGFEWNALIMVVVLGWVFVPIYIRA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMII 177
+ RF K ++I SI+ +++++ + + A +GA + LG+ I+ A++I +++
Sbjct: 132 LQKRFG--GKRIQIYLSILSLLLYIFTKISADIFSGAIFIQLTLGLDIYVAIIILLVITG 189
Query: 178 VYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN---- 233
+Y I GG AV Y D ++ IM++G V+L A +VGG E + P I+
Sbjct: 190 LYTITGGLAAVIYTDTLQTAIMMVGSVILTGFAFHEVGGYEAFTEKYMRAIPSQISYGNT 249
Query: 234 -------------------------PWAFGAGVVIG--FLGIGFGSPGQPHIIVRYMSID 266
PW G+V G L + + Q I+ R +S
Sbjct: 250 SIPQKCYTPREDAFHIFRDAITGDIPW---PGLVFGMSILTLWYWCTDQV-IVQRCLSAK 305
Query: 267 DPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD-VSQLPGKNAE-----------MI 314
+ + ++ ++ + V+ + + +G+ R + D V+ + E +
Sbjct: 306 NLSHVKAGCILCGYLKVMPMFLIVMMGMVSRILYTDKVACVVPSECERYCGTRVGCTNIA 365
Query: 315 YPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTA 374
+P L + P L G+++ + A+++S+ S ++ D+Y ++ KK + EK
Sbjct: 366 FPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKAS---EKEL 422
Query: 375 LTISRVTVL-VVGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
+ R+ +L ++G A I+ +F ++ LG +L+++WK +
Sbjct: 423 MIAGRLFMLFLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNE 482
Query: 431 ----WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATI 472
WG++ G ++G I Y ++P + LY + F+ S+I +
Sbjct: 483 PGAFWGLVLGFLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVISIITVV 542
Query: 473 IVSMITKPPENV 484
+VS+ TKP +V
Sbjct: 543 VVSLFTKPIPDV 554
>gb|AAF17249.1|AF208031_1 (AF208031) SGLT1 protein [Mus musculus]
Length = 665
Score = 119 bits (295), Expect = 8e-26
Identities = 122/552 (22%), Positives = 240/552 (43%), Gaps = 87/552 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
+YE ++N + + ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 19 SYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ +V + FV + I+ +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVVLGWIFVPIYIKA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMII 177
RF K ++I S++ +++++ + + A +GA ++ ALG+ I+ A+ I + +
Sbjct: 132 LRKRFG--GKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITA 189
Query: 178 VYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHALDPKLIN--- 233
+Y I GG AV Y D ++ IM++G +L A +VGG E + K + A+ K+ N
Sbjct: 190 LYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNF 249
Query: 234 -------------------------PWAFGAGVVIG--FLGIGFGSPGQPHIIVRYMSID 266
PW G++ G L + + Q I+ R +S
Sbjct: 250 TAKEECYTPRADSFHIFRDPITGDMPW---PGLIFGLAILALWYWCTDQV-IVQRCLSAK 305
Query: 267 DPNKLRVSTVVGTFWNVVLAWGAIFVGLAGR--------AIVPDVSQ----LPGKNAEMI 314
+ + ++ + + ++ + + G+ R ++P+ Q P +
Sbjct: 306 NMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIA 365
Query: 315 YPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTA 374
YP L + P L G+++ + A+++S+ S ++ D+Y ++ KK + EK
Sbjct: 366 YPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKAS---EKEL 422
Query: 375 LTISRVTVLV-VGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
+ R+ +LV +G A I+ +F ++ LG +L+++ K +
Sbjct: 423 MIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNE 482
Query: 431 ----WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATI 472
WG++ G ++G I Y ++P + LY + F+ S+I +
Sbjct: 483 QGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFVISVITIL 542
Query: 473 IVSMITKPPENV 484
I+S +TKP +V
Sbjct: 543 IISFLTKPIPDV 554
>dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Bacillus halodurans]
Length = 554
Score = 118 bits (293), Expect = 1e-25
Identities = 122/538 (22%), Positives = 220/538 (40%), Gaps = 90/538 (16%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
V+++ L T L I + Y R ++ DF+V R + ++ S+ +G++
Sbjct: 7 VSILMILATFGLYIGISIY--NRARATSDFYVASRGVPPFWNGMAIGGDWMSAASFIGMA 64
Query: 72 GMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILR 131
G +G + +G+ +F +LRK+ TVP++ R+ S R
Sbjct: 65 GTIMILGYDGLAYIMGWTGGYLFLTFLFAPQLRKYGR----YTVPEFIGDRYG--SNTAR 118
Query: 132 IAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYN 191
+ A+I II +Y+ Q + + L I MI V++I +Y LGG + +
Sbjct: 119 LIAAIATIIISFTYIIGQLSGSGVVIGRILNIPAMYGTMIGVVVIAIYATLGGMKGITWT 178
Query: 192 DVIRAVIMIIGLVVLPVIAVAKVGGTE-------EVLKVLHALDPKL-----INPWAFGA 239
V + +I+I+ ++ V ++ G + L LD +L + P F
Sbjct: 179 QVAQYIILIVAYIIPIVFMSLQLSGNPFPWLTYGNFISQLDGLDQELGLSQILQP--FME 236
Query: 240 GVVIGFLGIGF----GSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLA 295
F+ + F G+ PH+IVR+ + V+T+ W+ AW IF+ L
Sbjct: 237 SDKSQFIALMFTLMVGTAALPHVIVRFYT--------VTTMKAARWSG--AWALIFIALL 286
Query: 296 ----------GRAIV------PDVSQLPG---------------KNAEMIYPYLSAQYFP 324
R I+ + QLP N + I + +
Sbjct: 287 YLSAPAYAAFSRFILMTQVANQPIDQLPAWTEAWINTGLLEMADANGDGILQWEELRISN 346
Query: 325 PILY--------------GILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKID 370
I+ G++ G AA LSTA L+ ++S+ D+Y ++ K
Sbjct: 347 DIVVMATPEIANLGMFVIGLVAAGAMAAALSTAGGLLITISSSFAHDIYYRLMNP--KAS 404
Query: 371 EKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
++ L R+ +++ +A ++A +I V +A+G G +F P L+L ++WK
Sbjct: 405 DQKRLLAGRIAIVLATIVAGVVALDPPGVITQIVAWAFGLAGGAFFPVLLLGVWWKRANA 464
Query: 431 WGVLAGMIVGTITTIVWKLYLKPIT----GLYELVPAFI---FSLIATIIVSMITKPP 481
G +AGM+ G T+V+ + T G+ + I +L TI+VS++T P
Sbjct: 465 KGAIAGMLSGLAVTLVYIFLARTGTFTLFGIQDTGAGLIGVPVNLFVTIVVSLMTAAP 522
>pir||G83610 probable sodium:solute symporter PA0287 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946130|gb|AAG03676.1|AE004466_10 (AE004466)
probable sodium:solute symporter [Pseudomonas
aeruginosa]
Length = 461
Score = 117 bits (291), Expect = 2e-25
Identities = 115/476 (24%), Positives = 218/476 (45%), Gaps = 38/476 (7%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDK--ITVALSAVSSGRSSWLVLGLS 71
L+ ++ L + + +G+Y M++ KS+ DF V GR + ++AV G +S +G
Sbjct: 6 LIMLVYALAM-LGLGWYGMRKAKSQSDFLVAGRRLGPGLYLGTMAAVVLGGAS--TIGTV 62
Query: 72 GMAYKMGVTAVWAA----VGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTS 127
+ Y+ G++ +W +G IV + F RLR F TV E R++ +S
Sbjct: 63 KLGYQFGLSGLWLVFMLGLGIIVLSLV-FSRQIARLRVF-------TVTQVLEQRYQASS 114
Query: 128 KILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIA 187
++ I +++ L V A G+ T GI A++ ++IVY ++GG +
Sbjct: 115 RL--IGGVVMVAYDLMVAVTATIAIGSVT-EVVFGIPRIPAILCGGGIVIVYSVIGGMWS 171
Query: 188 VAYNDVIRAVIMIIG--LVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIG- 244
+ D+I+ VI +G LV+LP +++ GG + +VL A + G ++
Sbjct: 172 LTLTDIIQFVIKTVGIFLVLLP-LSIDGAGGLARMQEVLPA---GFFDLGHIGLDTILTY 227
Query: 245 FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVS 304
FL FG+ I R + +R + + + ++ +G A R ++PD++
Sbjct: 228 FLLYFFGALIGQDIWQRVFTARSETVVRYAGLGAGVYCMLYGAACALIGAAARVLLPDLA 287
Query: 305 QLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIK 364
E Y ++ + P L G+++ +AI+STA LL A+ + +D+Y ++
Sbjct: 288 V-----PENAYAEITREVLAPGLRGLVVAAALSAIMSTASGCLLAAATVLQEDIYARFLR 342
Query: 365 KGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLY 424
GT D + +SR L++G +LA + D+I + A+ L ++ +L
Sbjct: 343 PGTTSD----IRLSRCITLLMGVAMLVLACLVNDVIA-ALSIAYNLLVGGLLVPIVGALL 397
Query: 425 WKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMITKP 480
W+ + G +A ++ G + I + + +V + SL + VS+ T+P
Sbjct: 398 WRRASPQGAIASIVAGCLAVIAC-MARDGLLANSPIVYGLLASLATFVAVSLATRP 452
>pir||E83468 probable sodium:solute symport protein PA1418 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9947366|gb|AAG04807.1|AE004571_6 (AE004571) probable
sodium:solute symport protein [Pseudomonas aeruginosa]
Length = 463
Score = 117 bits (291), Expect = 2e-25
Identities = 109/471 (23%), Positives = 214/471 (45%), Gaps = 38/471 (8%)
Query: 25 ILVGFYAMKRTKSEEDFFVGGRAMDK---ITVALSAVSSGRSSWLVLGLSGMAYKMGVTA 81
I +G+Y M+R K+ +D+ V GR + + + V G S+ +G + Y G++
Sbjct: 16 IALGWYGMRRAKTRDDYLVAGRNLGPGFYLGTMAATVLGGAST---IGTVRLGYVHGISG 72
Query: 82 VW--AAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIII 139
W A+G + + F L K + TV E R+ ++ AS +I+
Sbjct: 73 FWLCGAIGLGIVGLSLF------LAKPLLKLKIYTVTQVLERRYNPAAR----HASALIM 122
Query: 140 IFLTSYVGAQFNAGAKTLSTAL-GISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVI 198
+ +GA T+ L G+ + +++I ++++Y +GG ++ D+++ +I
Sbjct: 123 LVYALMIGATSTIAIGTVMQVLFGLPFWVSILIGGGVVVLYSTIGGMWSLTLTDIVQFLI 182
Query: 199 MIIGLV-VLPVIAVAKVGGTEEVLKVLHA--LDPKLINPWAFGAGVVIGFLGIGFGSPGQ 255
M +GLV +L +++ GG + ++ L A D I +I F GI G
Sbjct: 183 MTVGLVFLLMPLSINDAGGWDALVAKLPASYFDFTAIGWDTIVTYFLIYFFGIFIGQ--- 239
Query: 256 PHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGKNAEMIY 315
I R + +V+ + V+ +G+A + ++PD+ + A ++
Sbjct: 240 -DIWQRVFTARSETVAKVAGSAAGIYCVLYGMAGALIGMAAKVLLPDLENVNNAFASVVE 298
Query: 316 PYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTAL 375
L P + G++I AA++STA + LL ++TV +DL +++G + +
Sbjct: 299 HSL-----PNGIRGLVIAAALAALMSTASAGLLAASTTVTQDLLPR-LRRGRGQSDNGDV 352
Query: 376 TISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLA 435
+R+ L++G + +A V D+I + A+ L LI ++YWK T G +
Sbjct: 353 HENRIATLLLGLVVLGIALVVSDVISALTV-AYNLLVGGMLIPLIGAIYWKRATTAGAIT 411
Query: 436 GMIVGTITTIVWKLY--LKPITGLYELVPAFIFSLIATIIVSMITKPPENV 484
M +G +T +V+ + L T +Y + L++ ++VS+ ++ P V
Sbjct: 412 SMTLGFLTVLVFMIKDGLDANTPIYY---SLAVGLLSFVLVSLFSRRPTGV 459
>emb|CAB59438.1| (AL132644) putative transmembrane transport protein [Streptomyces
coelicolor A3(2)]
Length = 544
Score = 117 bits (290), Expect = 3e-25
Identities = 111/472 (23%), Positives = 209/472 (43%), Gaps = 36/472 (7%)
Query: 11 PVALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGL 70
P+ + F ++ + + +A ++TK DF+ GGR L+ S+ LG+
Sbjct: 22 PLIITLFAVFVLATLGITVWAGRQTKDAADFYAGGRQFSAFQNGLAVSGDYMSAASFLGI 81
Query: 71 SGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKIL 130
+G G ++G++VA + + + LR S R+ T+ D R R + +
Sbjct: 82 AGAIALFGYDGFLYSIGFLVAWLVALLLVAEPLRN-SGRY---TMGDVLAYRMR--QRPV 135
Query: 131 RIAASIIIIIFLTSYVGAQFNAGAKTLSTALGIS-----IFTALMISVLMIIVYMILGGF 185
R AA I+ Y+ AQ +S LGI+ I ++ VLM IVY+ +GG
Sbjct: 136 RTAAGTSTIVVSIFYLLAQMAGAGILVSLLLGITSDAGKILIVALVGVLM-IVYVTIGGM 194
Query: 186 IAVAYNDVIRAVIMIIGLVVLPVIAVAK--------VGGTEEVLKVLHA-LDPKLINPWA 236
+ +++AV++I G +++ + + K +G E A L+P L +
Sbjct: 195 KGTTWVQMVKAVLLIGGTILITFLVLLKFDFNISDLLGKAAENSGAGSAFLEPGL--QYG 252
Query: 237 FGAGVVIGFLGIG----FGSPGQPHIIVRYMSIDDPNKLRVST-----VVGTFWNVVLAW 287
+ F+ +G G+ G PHI++R+ ++ + R S ++G F+ + +A
Sbjct: 253 ASGTTKLDFISLGIALVLGTAGLPHILIRFYTVPNAKAARKSVNWAIGIIGAFYLMTIAL 312
Query: 288 GAIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSA--QYFPPILYGILIGGIFAAILSTADS 345
G L G+ + + A ++ ++ + IL + FA IL+
Sbjct: 313 GFGAAALVGKDEIIASNPSGNTAAPLLALHVGGVDSTWGAILLATISAVAFATILAVVAG 372
Query: 346 QLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI-IFWFV 404
L +S+ D+Y VI+KG + EK + +R + +G ++ L +A+D+ + V
Sbjct: 373 LTLASSSSFAHDIYANVIRKG-QATEKEEMRAARWATVFIGIVSIALGALARDLNVAGLV 431
Query: 405 LFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITG 456
A+ ++ PT++ SL+WK T G L + G I + L+ ++G
Sbjct: 432 ALAFAVAASANLPTILYSLFWKRFTTQGALWSIYGGLIVAVGLVLFSPVVSG 483
>gi|6981552 solute carrier family 5, member alpha 1 (Na+/glucose cotransporter)
[Rattus norvegicus] >gi|1709218|sp|P53790|SL51_RAT
SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE
COTRANSPORTER 1) (HIGH AFFINITY SODIUM-GLUCOSE
COTRANSPORTER) >gi|1083725|pir||A53582 Na+/glucose
cotransporter SGLT1 - rat >gi|286259|dbj|BAA03676.1|
(D16101) Sodium/glucose cotransporter [Rattus
norvegicus] >gi|414572|gb|AAA19015.1| (U03120)
sodium-glucose cotransporter 1 [Rattus norvegicus]
Length = 665
Score = 115 bits (286), Expect = 9e-25
Identities = 119/552 (21%), Positives = 237/552 (42%), Gaps = 87/552 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
+YE ++N + + ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 19 SYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ ++V + FV + I+ +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMII 177
RF K ++I S++ +++++ + + A +GA ++ ALG+ I+ A+ I + +
Sbjct: 132 LRKRFG--GKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITA 189
Query: 178 VYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN---- 233
+Y I GG AV Y D ++ IM++G +L A +VGG E + P L++
Sbjct: 190 LYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNI 249
Query: 234 -------------------------PWAFGAGVVIG--FLGIGFGSPGQPHIIVRYMSID 266
PW G++ G L + + Q I+ R +S
Sbjct: 250 TVKEECYTPRADSFHIFRDPITGDMPW---PGLIFGLSILALWYWCTDQV-IVQRCLSAK 305
Query: 267 DPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD--VSQLPGK----------NAEMI 314
+ + ++ + + ++ + + G+ R + D LP + +
Sbjct: 306 NMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIA 365
Query: 315 YPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTA 374
YP L + P L G+++ + A+++S+ S ++ D+Y + I+KG EK
Sbjct: 366 YPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTK-IRKGA--SEKEL 422
Query: 375 LTISRVTVLV-VGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
+ R+ +LV +G A I+ +F ++ LG +L+++ K +
Sbjct: 423 MIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNE 482
Query: 431 ----WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATI 472
WG++ G ++G I Y ++P + LY + F S++ +
Sbjct: 483 PGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVL 542
Query: 473 IVSMITKPPENV 484
++S++TKP +V
Sbjct: 543 VISLLTKPIPDV 554
>dbj|BAA19172.1| (AB000729) Na/glucose cotransporter [Rattus norvegicus]
Length = 665
Score = 115 bits (286), Expect = 9e-25
Identities = 119/552 (21%), Positives = 237/552 (42%), Gaps = 87/552 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
+YE ++N + + ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 19 SYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ ++V + FV + I+ +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMII 177
RF K ++I S++ +++++ + + A +GA ++ ALG+ I+ A+ I + +
Sbjct: 132 LRKRFG--GKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITA 189
Query: 178 VYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN---- 233
+Y I GG AV Y D ++ IM++G +L A +VGG E + P L++
Sbjct: 190 LYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNI 249
Query: 234 -------------------------PWAFGAGVVIG--FLGIGFGSPGQPHIIVRYMSID 266
PW G++ G L + + Q I+ R +S
Sbjct: 250 TVKEECYTPRADSFHIFRDPITGDMPW---PGLIFGLSILALWYWCTDQV-IVQRCLSAK 305
Query: 267 DPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD--VSQLPGK----------NAEMI 314
+ + ++ + + ++ + + G+ R + D LP + +
Sbjct: 306 NMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKHCGTPVGCTNIA 365
Query: 315 YPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTA 374
YP L + P L G+++ + A+++S+ S ++ D+Y + I+KG EK
Sbjct: 366 YPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTK-IRKGA--SEKEL 422
Query: 375 LTISRVTVLV-VGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
+ R+ +LV +G A I+ +F ++ LG +L+++ K +
Sbjct: 423 MIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNE 482
Query: 431 ----WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATI 472
WG++ G ++G I Y ++P + LY + F S++ +
Sbjct: 483 PGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVL 542
Query: 473 IVSMITKPPENV 484
++S++TKP +V
Sbjct: 543 VISLLTKPIPDV 554
>emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Streptomyces
coelicolor A3(2)]
Length = 562
Score = 115 bits (286), Expect = 9e-25
Identities = 111/500 (22%), Positives = 220/500 (43%), Gaps = 48/500 (9%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
++ F ++L I GF A + ++ DFF+ GR++ L+ V++ + +LG++
Sbjct: 25 ILGIYFVVVLGI--GFAARRSVRTSLDFFLSGRSLPAWVTGLAFVAANLGATEILGMAAN 82
Query: 74 AYKMGV-TAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
+ + GV T W +G I A V++G+ + F +VP++ RF S +L
Sbjct: 83 SAQYGVYTTHWYWIGAIPA----MVFLGLVMMPFYYGSKVRSVPEFLLLRFDKASHLLSS 138
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
A I I + G A A + LG + A++++ ++ Y+ LGG + YN+
Sbjct: 139 ALFAIAAILIA---GVNLYALAIVVEALLGWPEWVAIVVAGFFVLAYITLGGLSSAIYNE 195
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTE---EVLKVLHALDPKLINPWA---------FGAG 240
V++ +++ GL+ + ++ + KVGG + + L H D + W GA
Sbjct: 196 VLQFFVILAGLIPITILGLKKVGGWDGLSDSLSKSHGSD--FMTAWGGTGIGSENPLGAN 253
Query: 241 VVIGFLGIGFG-SPGQPHI----IVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLA 295
+ LG+GF S G + R +S + + + + ++ F + + + + GL
Sbjct: 254 WLTIVLGLGFVLSFGYWTTNFAEVQRALSAKNLSAAQRTPLIAAFPKIFIVFVVMIPGLV 313
Query: 296 GRAIVPDVSQLPGKNAEM--IYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVAST 353
+VP + PG + + PYL Q P + GI + G+ AA ++ + + +
Sbjct: 314 AAVLVPKIG-TPGSDLQYNDAIPYLMQQLLPNGVLGIAVTGLLAAFMAGMAANISSFNTV 372
Query: 354 VVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAI-LAYVAKDI--IFWFVLFAWGG 410
D++Q+ + K ++ + R+ + V+G LA+I A++A I ++ +
Sbjct: 373 FTTDIWQKYVVKDR--EDGYYVRFGRL-ITVIGVLASIGTAFLASSFSNIMSYLQTLFSF 429
Query: 411 LGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIV--WKLYLKPI--------TGLYEL 460
I+ ++WK + G+I GT +V + +Y + I
Sbjct: 430 FNVPMFVVFIIGMFWKRASMKSGFWGLIAGTTAAMVNYFVIYKQGIIDIPSDQGANFVSA 489
Query: 461 VPAFIFSLIATIIVSMITKP 480
+ F+ + + VS+ T P
Sbjct: 490 IAGFVAGAVVMVAVSLFTAP 509
>gi|11528510 solute carrier family 5 (choline transporter), member 7 [Mus
musculus] >gi|9843809|emb|CAC03719.1| (AJ401467) high
affinity choline transporter [Mus musculus]
Length = 580
Score = 115 bits (284), Expect = 2e-24
Identities = 116/469 (24%), Positives = 207/469 (43%), Gaps = 45/469 (9%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSE-------EDFFVGGRAMDKITVALSAVSSGRSSWL 66
LVA + +L LVG +A +TK+ E VGGR + + + ++
Sbjct: 8 LVAIILFYLLIFLVGIWAAWKTKNSGNPEEHSEAIIVGGRDIGLLVGGFTMTATWVGGGY 67
Query: 67 VLGLSGMAYKMGVTAVWAA--VGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+ G + Y G WA +GY ++ + G+ K +T+ D F+ +
Sbjct: 68 INGTAVAVYGPGCGLAWAQAPIGYSLS----LILGGLFFAKPMRSKGYVTMLDPFQQIYG 123
Query: 125 DTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGG 184
L +++ +F + A F+A T+S + + + ++++S L+ I+Y ++GG
Sbjct: 124 KRMGGLLFIPALMGEMF---WAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGG 180
Query: 185 FIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVV-- 242
+VAY DV++ + IGL + A++ T+ +HA K +PW V
Sbjct: 181 LYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHA---KYQSPWLGTIESVEV 237
Query: 243 ----IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRA 298
FL + G R +S +V + + F +V+A AI +G G +
Sbjct: 238 YTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSYLAAFGCLVMALPAICIGAIGAS 297
Query: 299 I--------VPDVSQLPGKNAEMIYPYLSAQYFPPILYGIL-IGGIFAAILSTADSQLLV 349
PD + A+MI P + QY P+ +G + AA++S+ADS +L
Sbjct: 298 TDWNQTAYGYPDPK--TKEEADMILP-IVLQYLCPVYISFFGLGAVSAAVMSSADSSILS 354
Query: 350 VASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDII-FWFVLFAW 408
+S +++YQ ++ +K + + R+TVLV G A +A + K + W++ +
Sbjct: 355 ASSMFARNIYQLSFRQNA--SDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYL--SS 410
Query: 409 GGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVW---KLYLKPI 454
+ P L+ L+ KGT +G +AG I G I LYL+P+
Sbjct: 411 DLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPL 459
>gb|AAG36945.1| (AF276872) sodium and chloride-dependent high-affinity choline
transporter [Mus musculus]
Length = 580
Score = 115 bits (284), Expect = 2e-24
Identities = 116/469 (24%), Positives = 207/469 (43%), Gaps = 45/469 (9%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSE-------EDFFVGGRAMDKITVALSAVSSGRSSWL 66
LVA + +L LVG +A +TK+ E VGGR + + + ++
Sbjct: 8 LVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGY 67
Query: 67 VLGLSGMAYKMGVTAVWA--AVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+ G + Y G WA +GY ++ + G+ K +T+ D F+ +
Sbjct: 68 INGTAEAVYGPGCGLAWAHAPIGYSLS----LILGGLFFAKPMRSKGYVTMLDPFKQIYG 123
Query: 125 DTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGG 184
L +++ +F + A F+A T+S + + + ++++S L+ I+Y ++GG
Sbjct: 124 KRMGGLLFIPALMGEMF---WAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGG 180
Query: 185 FIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVV-- 242
+VAY DV++ + IGL + A++ T+ +HA K +PW V
Sbjct: 181 LYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHA---KYQSPWLGTIESVEV 237
Query: 243 ----IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRA 298
FL + G R +S +V + + F +V+A AI +G G +
Sbjct: 238 YTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGAS 297
Query: 299 I--------VPDVSQLPGKNAEMIYPYLSAQYFPPILYGIL-IGGIFAAILSTADSQLLV 349
PD + A+MI P + QY P+ +G + AA++S+ADS +L
Sbjct: 298 TDWNQTAYGYPDPK--TKEEADMILP-IVLQYLCPVYISFFGLGAVSAAVMSSADSSILS 354
Query: 350 VASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDII-FWFVLFAW 408
+S +++YQ ++ +K + + R+TVLV G A +A + K + W++ +
Sbjct: 355 ASSMFARNIYQLSFRQNA--SDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYL--SS 410
Query: 409 GGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVW---KLYLKPI 454
+ P L+ L+ KGT +G +AG I G I LYL+P+
Sbjct: 411 DLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPL 459
>gi|8394316 solute carrier family 5, member alpha 3 [Mus musculus]
>gi|7248788|gb|AAF43668.1|AF220915_1 (AF220915)
osmoregulatory Na+/myo-inositol cotransporter [Mus
musculus]
Length = 718
Score = 114 bits (282), Expect = 3e-24
Identities = 115/540 (21%), Positives = 233/540 (42%), Gaps = 83/540 (15%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+A+VA F L++ +GF+AM ++ +F+ GR+M + + S S S +G
Sbjct: 10 IAVVALYFILVM--CIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIG 67
Query: 70 LSGMAYKMG-VTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
L+G G W ++ ++ +V++ I +R T+P+Y RF +
Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRS-----GVYTMPEYLSKRFGG-HR 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I A++ +++++ + + +GA + +LG +++ ++++ + M + + GG +AV
Sbjct: 122 IQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN--------------- 233
Y D ++A++MIIG + L VI++ K+GG EEV + P + +
Sbjct: 182 IYTDTLQALLMIIGALTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYNLSNTNACMV 241
Query: 234 ------------------PWAFGAGVVIGF--LGIGFGSPGQPHIIVRYMSIDDPNKLRV 273
PW G ++G + + Q I+ R ++ + +
Sbjct: 242 HPKANALKMLRDPTDEDVPW---PGFILGQTPASVWYWCADQV-IVQRVLAAKNIAHAKG 297
Query: 274 STVVGTFWNVVLAWGAIFVGLAGRAIVPD---------VSQLPGKNA---EMIYPYLSAQ 321
ST++ F ++ + + G+ R + D Q+ G A + YP L
Sbjct: 298 STLMAGFLKLLPMFIIVVPGMISRIVFADEIACINPEHCMQVCGSRAGCSNIAYPRLVMT 357
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
P L G+++ + AA++S DS ++ D+Y ++I+K E + V
Sbjct: 358 LVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVY-KLIRKSASSRELMIVGRIFVA 416
Query: 382 VLVVGFLA--AILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLA 435
+VV +A I+ + ++ ++ L +L+++WK + +G +A
Sbjct: 417 FMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMA 476
Query: 436 GMIVGTITTIVWKLY--------------LKPITGLYELVPAFIFSLIATIIVSMITKPP 481
G ++G + I+ Y +K I +Y F + + T+IVS++T PP
Sbjct: 477 GFVLGAVRLILAFTYRAPECDQPDNRPGFIKDIHYMYVATALFWITGLITVIVSLLTPPP 536
>gi|4507031 solute carrier family 5 (sodium/glucose cotransporter), member 1;
Human Na+/glucose cotransporter 1 mRNA, complete cds;
solute carrier family 5 (sodium/glucose transporter),
member 1 [Homo sapiens] >gi|11418010|ref|XP_009937.1|
solute carrier family 5 (sodium/glucose cotransporter),
member 1 [Homo sapiens] >gi|127803|sp|P13866|SL51_HUMAN
SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE
COTRANSPORTER 1) (HIGH AFFINITY SODIUM-GLUCOSE
COTRANSPORTER) >gi|106106|pir||A33545 Na+/glucose
cotransporter SGLT1 - human >gi|338055|gb|AAA60320.1|
(M24847) Na+/glucose cotransporter [Homo sapiens]
>gi|529056|gb|AAB59448.1| (L29339) Na+/glucose
cotransporter [Homo sapiens] >gi|3646043|emb|CAB06087.1|
(Z83839) dJ127L4.1 (solute carrier family 5
(sodium/glucose cotransporter), member 1 (SGLT1, High
Affinity Sodium-Glucose Cotransporter)) [Homo sapiens]
Length = 664
Score = 113 bits (281), Expect = 4e-24
Identities = 114/550 (20%), Positives = 239/550 (42%), Gaps = 85/550 (15%)
Query: 5 YEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGR 62
+E+++N + + ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 20 HELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNI 79
Query: 63 SSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYF 119
S +GL+G G+ W A+ +V + FV + I+ +T+P+Y
Sbjct: 80 GSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKA-------GVVTMPEYL 132
Query: 120 EARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVY 179
RF +I + + +++++ + + A +GA ++ ALG++++ A+ + + + +Y
Sbjct: 133 RKRFGG-QRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALY 191
Query: 180 MILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN------ 233
I GG AV Y D ++ VIM++G ++L A +VGG + ++ P +++
Sbjct: 192 TITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTF 251
Query: 234 -----------------------PWAFGAGVVIG--FLGIGFGSPGQPHIIVRYMSIDDP 268
PW G + G L + + Q I+ R +S +
Sbjct: 252 QEKCYTPRADSFHIFRDPLTGDLPW---PGFIFGMSILTLWYWCTDQV-IVQRCLSAKNM 307
Query: 269 NKLRVSTVVGTFWNVVLAWGAIFVGLAGR--------AIVP-DVSQLPGKN---AEMIYP 316
+ ++ ++ + ++ + + G+ R +VP + + G + YP
Sbjct: 308 SHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYP 367
Query: 317 YLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALT 376
L + P L G+++ + A+++S+ S ++ D+Y +V K+ + EK +
Sbjct: 368 TLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRAS---EKELMI 424
Query: 377 ISRVTVLV-VGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK-- 430
R+ +LV +G A I+ +F ++ LG +L+++WK +
Sbjct: 425 AGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPG 484
Query: 431 --WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATIIV 474
WG++ G+++G I Y ++P + LY + F S I +++
Sbjct: 485 AFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVI 544
Query: 475 SMITKPPENV 484
S++TKP +V
Sbjct: 545 SLLTKPIPDV 554
>dbj|BAA90484.1| (AB030947) high-affinity choline transporter CHT1 [Rattus
norvegicus]
Length = 580
Score = 113 bits (281), Expect = 4e-24
Identities = 115/469 (24%), Positives = 206/469 (43%), Gaps = 45/469 (9%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSE-------EDFFVGGRAMDKITVALSAVSSGRSSWL 66
LVA + +L LVG +A +TK+ E VGGR + + + ++
Sbjct: 8 LVAIILFYLLIFLVGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGY 67
Query: 67 VLGLSGMAYKMGVTAVWAA--VGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+ G + Y G WA +GY ++ + G+ K +T+ D F+ +
Sbjct: 68 INGTAEAVYGPGCGLAWAQAPIGYSLS----LILGGLFFAKPMRSKGYVTMLDPFQQIYG 123
Query: 125 DTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGG 184
L +++ +F + A F+A T+S + + + ++++S L+ I+Y ++GG
Sbjct: 124 KRMGGLLFIPALMGEMF---WAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGG 180
Query: 185 FIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVV-- 242
+VAY DV++ + IGL + A++ T+ +HA K +PW V
Sbjct: 181 LYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHA---KYQSPWLGTIESVEV 237
Query: 243 ----IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRA 298
FL + G R +S +V + + F +V+A AI +G G +
Sbjct: 238 YTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGAS 297
Query: 299 I--------VPDVSQLPGKNAEMIYPYLSAQYFPPILYGIL-IGGIFAAILSTADSQLLV 349
PD + A+MI P + QY P+ +G + AA++S+ADS +L
Sbjct: 298 TDWNQTAYGFPDPK--TKEEADMILP-IVLQYLCPVYISFFGLGAVSAAVMSSADSSILS 354
Query: 350 VASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDII-FWFVLFAW 408
+S +++YQ ++ +K + + R+TV V G A +A + K + W++ +
Sbjct: 355 ASSMFARNIYQLSFRQNA--SDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYL--SS 410
Query: 409 GGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVW---KLYLKPI 454
+ P L+ L+ KGT +G +AG I G I LYL+P+
Sbjct: 411 DLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPL 459
>gi|9790215 sodium-glucose cotransporter 1 [Mus musculus]
>gi|6681727|gb|AAF23269.1| (AF163846) sodium-glucose
cotransporter 1 [Mus musculus]
Length = 665
Score = 113 bits (279), Expect = 6e-24
Identities = 121/552 (21%), Positives = 235/552 (41%), Gaps = 87/552 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
+YE ++N ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 19 SYERIRNAADTSVIAIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ +V + FV + I+ +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVVLGWIFVPIYIKA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMII 177
RF K ++I S++ +++++ + + A +GA ++ LG+ I+ A+ I + +
Sbjct: 132 LRKRFG--GKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLTLGLDIYLAIFILLAITA 189
Query: 178 VYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHALDPKLIN--- 233
+Y I GG AV Y D ++ IM++G +L A +VGG E + K + A+ K+ N
Sbjct: 190 LYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNL 249
Query: 234 -------------------------PWAFGAGVVIG--FLGIGFGSPGQPHIIVRYMSID 266
PW G++ G L + + Q I+ R +S
Sbjct: 250 TAKEECYTPRADSFHIFRDPITGDMPW---PGLIFGLAILALWYWCTDQV-IVQRCLSAK 305
Query: 267 DPNKLRVSTVVGTFWNVVLAWGAIFVGLAGR--------AIVPDVSQ----LPGKNAEMI 314
+ + ++ + + ++ + + G+ R ++P+ Q P
Sbjct: 306 NMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCPTSA 365
Query: 315 YPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTA 374
P L + P L G+ + G+ A+++S+ S ++ D+Y ++ KK + EK
Sbjct: 366 TPTLVVELMPNGLQGLKLSGMMASLMSSLTSIFNSASTLFTMDIYTKIRKKAS---EKEL 422
Query: 375 LTISRVTVLV-VGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK 430
+ R+ +LV +G A I+ +F ++ LG +L+++ K +
Sbjct: 423 MIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNE 482
Query: 431 ----WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATI 472
WG++ G ++G I Y ++P + LY + F+ S+I +
Sbjct: 483 QGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFVISVITIL 542
Query: 473 IVSMITKPPENV 484
I+S +TKP +V
Sbjct: 543 IISFLTKPIPDV 554
>gi|11526219 solute carrier family 5 (inositol transporters), member 3 [Homo
sapiens] >gi|3334498|sp|P53794|SL53_HUMAN
SODIUM/MYO-INOSITOL COTRANSPORTER (NA(+)/MYO-INOSITOL
COTRANSPORTER) >gi|2739094|gb|AAC39548.1| (AF027153)
sodium/myo-inositol cotransporter [Homo sapiens]
Length = 718
Score = 113 bits (279), Expect = 6e-24
Identities = 112/540 (20%), Positives = 237/540 (43%), Gaps = 83/540 (15%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+A+VA F L++ +GF+AM ++ +F+ GR+M +T+ S S S +G
Sbjct: 10 IAIVALYFILVM--CIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67
Query: 70 LSGMAYKMG-VTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
L+G G W ++ ++ +V++ I +R T+P+Y RF +
Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRS-----GVYTMPEYLSKRFGG-HR 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I A++ +I+++ + + +GA + +LG +++ ++++ + M + + GG +AV
Sbjct: 122 IQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN--------------- 233
Y D ++A++MIIG + L +I++ ++GG EEV + P + +
Sbjct: 182 IYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNV 241
Query: 234 ------------------PWAFGAGVVIGF--LGIGFGSPGQPHIIVRYMSIDDPNKLRV 273
PW G ++G + + Q I+ R ++ + +
Sbjct: 242 SPKKEALKMLRNPTDEDVPW---PGFILGQTPASVWYWCADQV-IVQRVLAAKNIAHAKG 297
Query: 274 STVVGTFWNVVLAWGAIFVGLAGRAI-VPDVSQLPGKNAEMI-----------YPYLSAQ 321
ST++ F ++ + + G+ R + D++ + ++ ++ YP L +
Sbjct: 298 STLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMK 357
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
P L G+++ + AA++S DS ++ D+Y ++I+K E + V
Sbjct: 358 LVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVY-KLIRKSASSRELMIVGRIFVA 416
Query: 382 VLVVGFLA--AILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLA 435
+VV +A I+ + ++ ++ L +L+++WK + +G +A
Sbjct: 417 FMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMA 476
Query: 436 GMIVGTITTIVWKLY--------------LKPITGLYELVPAFIFSLIATIIVSMITKPP 481
G ++G + I+ Y +K I +Y F + + T+IVS++T PP
Sbjct: 477 GFVLGAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPP 536
>pir||H75513 probable sodium/proline symporter DR0477 [similarity] - Deinococcus
radiodurans (strain R1)
>gi|6458165|gb|AAF10057.1|AE001907_3 (AE001907)
sodium:solute symporter protein [Deinococcus
radiodurans]
Length = 528
Score = 112 bits (278), Expect = 8e-24
Identities = 111/461 (24%), Positives = 201/461 (43%), Gaps = 48/461 (10%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
L+A L LI + V F+A R S DF+V G + ++ S+ LG++G+
Sbjct: 4 LLAALIVLIT-LGVTFWASSRNTSAGDFYVAGGKISATQNGIAIAGDYMSAASFLGITGL 62
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133
G +VG+ +A + + LR + T+ D R +D +R
Sbjct: 63 IALNGYDGFMYSVGWFIAYLTVLFIVAEPLRNLGK----YTLADMLVYRLKDQR--VRFY 116
Query: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISV--LMIIVYMILGGFIAVAYN 191
A+ I T Y+ AQ +S G + L I + L++IVY+++GG +A +
Sbjct: 117 AAFSTITVSTFYMIAQVVGAGSLISLLSGGLLKPTLAIPLVGLLMIVYVVVGGMLATTWV 176
Query: 192 DVIRAVIMIIGLVVLPVIAVAKVG-------GTEEVLKVLHALDP--KLINPWAFGAGVV 242
+I+A++++ +V+ V+ +A+ G G L+P K NP ++
Sbjct: 177 QIIKAMLLMFATIVMSVLILARFGFSFSDLLGAATDKNGAAFLEPGLKYKNP----LDLI 232
Query: 243 IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVV-----GTFWNVVLAWG---AIFVGL 294
L + G+ G PHI+VR+ ++ R S VV G F+ + G + VG
Sbjct: 233 SLCLALVLGTAGLPHILVRFFTVPTAQDARKSVVVAMGLIGAFYIMTALMGNAANVLVGK 292
Query: 295 --------AGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQ 346
AG P ++Q G A + + + FA IL+
Sbjct: 293 DTIVAANPAGNMAAPLLAQALGGGAGTLGGEFGLAFVTAV--------AFATILAVVAGL 344
Query: 347 LLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKD-IIFWFVL 405
+ +++ D+Y V+ KG K +E+ ++R+ + VG L+ +L +AKD + + V
Sbjct: 345 TISASTSFTHDIYNGVM-KGGKANEQEQFKVARMATVAVGLLSIVLGLLAKDQNVAFLVA 403
Query: 406 FAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIV 446
A+ ++ P ++ +L+W+G G + G++ G T+V
Sbjct: 404 LAFAIAASANLPVILYTLFWRGFNANGAVWGIVGGLAVTLV 444
>sp|P53793|SL53_BOVIN SODIUM/MYO-INOSITOL COTRANSPORTER (NA(+)/MYO-INOSITOL
COTRANSPORTER) >gi|1237437|gb|AAA93188.1| (U41338)
Na+/myo-inositol cotransporter [Bos taurus]
Length = 718
Score = 112 bits (277), Expect = 1e-23
Identities = 112/540 (20%), Positives = 231/540 (42%), Gaps = 83/540 (15%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+A+VA F L++ +GF+AM ++ +F+ GR+M + + S S S +G
Sbjct: 10 IAIVALYFILVM--CIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIG 67
Query: 70 LSGMAYKMG-VTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
L+G G W ++ ++ +V++ I +R T+P+Y RF +
Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRS-----GVYTMPEYLSKRFGG-HR 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I A++ +I+++ + + +GA + ++G +++ ++++ + M + + GG +AV
Sbjct: 122 IQVYFAALSLILYIFTKLSVDLYSGALFIQESMGWNLYVSVILLIGMTALLTVTGGLVAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN--------------- 233
Y D ++A++MI+G + L VI++ ++GG EEV + P + +
Sbjct: 182 IYTDTLQALLMIVGALTLMVISMMEIGGFEEVKRRYMLASPNVTSILLTYNLSNTNSCNV 241
Query: 234 ------------------PWAFGAGVVIGF--LGIGFGSPGQPHIIVRYMSIDDPNKLRV 273
PW G ++G + + Q I+ R ++ + +
Sbjct: 242 HPKKDALKMLRNPTDEDVPW---PGFILGQTPASVWYWCADQV-IVQRVLAAKNIAHAKG 297
Query: 274 STVVGTFWNVVLAWGAIFVGLAGRAIVPD---------VSQLPGKNA---EMIYPYLSAQ 321
ST++ F ++ + + G+ R + D Q+ G A + YP L +
Sbjct: 298 STLMAGFLKLLPMFIIVVPGMISRILFADDIACINPEHCMQVCGSRAGCSNIAYPRLVMK 357
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
P L G+++ + AA++S DS ++ D+Y ++I+K E + V
Sbjct: 358 LVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVY-KLIRKSASSRELMIVGRIFVA 416
Query: 382 VLVVGFLA--AILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIV 439
+VV +A I+ + ++ ++ L +L+++WK + G G +
Sbjct: 417 FMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMA 476
Query: 440 GTITTIV------------------WKLYLKPITGLYELVPAFIFSLIATIIVSMITKPP 481
G I +V +++K I +Y F + + T+IVS++T PP
Sbjct: 477 GFILVVVRLTLAFAYRAPECDQPDNRPVFIKDIHYMYVATALFWITGLITVIVSLLTPPP 536
>gi|5902092 solute carrier family 5 (inositol transporters), member 3; solute
carrier family 5 (inositol transporter), member 3; human
solute carrier family 5, member 3, Sodium/myo-inositol
cotransporter [Homo sapiens] >gi|1082630|pir||A56851
Na+/myo-inositol cotransporter - human
>gi|662843|gb|AAC41747.1| (L38500) Na+/myo-inositol
cotransporter [Homo sapiens]
Length = 718
Score = 112 bits (277), Expect = 1e-23
Identities = 112/540 (20%), Positives = 236/540 (42%), Gaps = 83/540 (15%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+A+VA F L++ +GF+AM + +F+ GR+M +T+ S S S +G
Sbjct: 10 IAIVALYFILVM--CIGFFAMWKCNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67
Query: 70 LSGMAYKMG-VTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
L+G G W ++ ++ +V++ I +R T+P+Y RF +
Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRS-----GVYTMPEYLSKRFGG-HR 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I A++ +I+++ + + +GA + +LG +++ ++++ + M + + GG +AV
Sbjct: 122 IQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN--------------- 233
Y D ++A++MIIG + L +I++ ++GG EEV + P + +
Sbjct: 182 IYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNV 241
Query: 234 ------------------PWAFGAGVVIGF--LGIGFGSPGQPHIIVRYMSIDDPNKLRV 273
PW G ++G + + Q I+ R ++ + +
Sbjct: 242 SPKKEALKMLRNPTDEDVPW---PGFILGQTPASVWYWCADQV-IVQRVLAAKNIAHAKG 297
Query: 274 STVVGTFWNVVLAWGAIFVGLAGRAI-VPDVSQLPGKNAEMI-----------YPYLSAQ 321
ST++ F ++ + + G+ R + D++ + ++ ++ YP L +
Sbjct: 298 STLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMK 357
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
P L G+++ + AA++S DS ++ D+Y ++I+K E + V
Sbjct: 358 LVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVY-KLIRKSASSRELMIVGRIFVA 416
Query: 382 VLVVGFLA--AILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLA 435
+VV +A I+ + ++ ++ L +L+++WK + +G +A
Sbjct: 417 FMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMA 476
Query: 436 GMIVGTITTIVWKLY--------------LKPITGLYELVPAFIFSLIATIIVSMITKPP 481
G ++G + I+ Y +K I +Y F + + T+IVS++T PP
Sbjct: 477 GFVLGAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPP 536
>gi|11141885 solute carrier family 5 (choline transporter), member 7; high
affinity choline transporter; hemicholinium-3-sensitive
choline transporter [Homo sapiens]
>gi|9843754|emb|CAC03717.1| (AJ401466) high affinity
choline transporter [Homo sapiens]
>gi|10998442|gb|AAG25940.1| (AF276871) high affinity
choline transporter [Homo sapiens]
>gi|11231081|dbj|BAB18161.1| (AB043997) high-affinity
choline transporter CHT1 [Homo sapiens]
Length = 580
Score = 112 bits (277), Expect = 1e-23
Identities = 115/472 (24%), Positives = 208/472 (43%), Gaps = 51/472 (10%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSE-------EDFFVGGRAMDKITVALSAVSSGRSSWL 66
L+A + +L +LVG +A RTK+ E VGGR + + + ++
Sbjct: 8 LIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGY 67
Query: 67 VLGLSGMAYKMGVTAVWAA--VGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+ G + Y G WA +GY ++ + G+ K +T+ D F+ +
Sbjct: 68 INGTAEAVYVPGYGLAWAQAPIGYSLS----LILGGLFFAKPMRSKGYVTMLDPFQQIYG 123
Query: 125 DTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGG 184
L +++ +F + A F+A T+S + + + +++IS L+ +Y ++GG
Sbjct: 124 KRMGGLLFIPALMGEMF---WAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG 180
Query: 185 FIAVAYNDVIRAVIMIIGLVV-----LPVIAVAKVGGTEEVLKV----LHALDPKLINPW 235
+VAY DV++ + +GL + L AVA +G T K L +D + W
Sbjct: 181 LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW 240
Query: 236 AFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLA 295
+ FL + G R +S +V + + F +V+A AI +G
Sbjct: 241 ------LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAI 294
Query: 296 GRAI--------VPDVSQLPGKNAEMIYPYLSAQYFPPILYGIL-IGGIFAAILSTADSQ 346
G + +PD + A+MI P + QY P+ +G + AA++S+ADS
Sbjct: 295 GASTDWNQTAYGLPDPKTT--EEADMILP-IVLQYLCPVYISFFGLGAVSAAVMSSADSS 351
Query: 347 LLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDII-FWFVL 405
+L +S +++YQ ++ +K + + R+TV V G A +A + K + W++
Sbjct: 352 ILSASSMFARNIYQLSFRQNA--SDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYL- 408
Query: 406 FAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVW---KLYLKPI 454
+ + P L+ L+ KGT +G +AG + G I LYL+P+
Sbjct: 409 -SSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPL 459
>pir||T35201 probable transmembrane transport - Streptomyces coelicolor
>gi|3036892|emb|CAA18525.1| (AL022374) SC5B8.17,
probable transmembrane transport protein, len: 530 aa;
member of the sodium:solute symporter family, similar to
many e.g. YJCG_ECOLI P32705 hypothetical protein , (549
aa), fasta scores; opt: 935 z-score: 1534.8 E(): 0,
43.6% ident>
Length = 530
Score = 111 bits (276), Expect = 1e-23
Identities = 113/477 (23%), Positives = 216/477 (44%), Gaps = 49/477 (10%)
Query: 14 LVAFLFTLILPILVG---FYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGL 70
L LF+ + + +G + +R S E+F+ GGR + + S+ LG+
Sbjct: 8 LALLLFSTFVAVTLGITTWVGRRRQGSAEEFYAGGRLFSPMENGFAISGDYMSAASFLGI 67
Query: 71 SGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKIL 130
SG+ G + +VG++VA + +++ L + RF T+ D AR R+ + +
Sbjct: 68 SGLIALNGYDGMLYSVGFLVAWLV-VLFLVAELVRNCGRF---TLADVVAARMRE--RPV 121
Query: 131 RIAASIIIIIFLTSYVGAQFNAGAKTLSTALG-----ISIFTALMISVLMIIVYMILGGF 185
RIAA + Y+ AQ ++ LG +T + + LM+I Y+ LGG
Sbjct: 122 RIAAGTSSVTVSVLYLVAQMVGAGSLVALLLGGTSEAARTWTVIGVGALMVI-YVSLGGM 180
Query: 186 IAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGA-GVVIG 244
A + +++AV+++ G V L + + + G +V ++L + + AF A G+ G
Sbjct: 181 RATTWIQIVKAVLLLGGTVALTALVLVRFHG--DVDRLLRTAAERSGHGEAFLAPGLAYG 238
Query: 245 --------FLGIG----FGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWG---- 288
F+ +G G+ G PHI+ R+ ++ R S V W++ L G
Sbjct: 239 GDWVARFDFISLGLALVLGTAGLPHILSRFYTVPTARAARRSVV----WSIGLIGGFYLM 294
Query: 289 AIFVGLAGRAIV-PDVSQLPGKNAEMIYPYLSAQY-------FPPILYGILIGGIFAAIL 340
I +G A+V P+ + P L+ +L+ ++ FA IL
Sbjct: 295 TIVLGFGAAALVGPNAVRASNAAGNTAVPLLALDLGGGAHSTGGTVLFAVVAAVAFATIL 354
Query: 341 STADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI- 399
+ L +++V DLY + ++ +K ++ + ++RV + +G +A L +A+D+
Sbjct: 355 AVVAGITLASSASVAHDLYASLRRRHSK--PRSEVAVARVAAVGIGAVAIGLGLLARDLN 412
Query: 400 IFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITG 456
+ + V A+ ++ P L+ SL+W+G T G + + G + ++V L ++G
Sbjct: 413 VAFLVGLAFAVAASANLPVLLYSLFWRGFTTRGAVWAVYGGLVPSVVLVLLSPVVSG 469
>gb|AAB68775.1| (U95125) Na+/myo-inositol cotransporter [Bos taurus]
Length = 718
Score = 111 bits (275), Expect = 2e-23
Identities = 113/542 (20%), Positives = 238/542 (43%), Gaps = 87/542 (16%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+A+VA F L++ +GF+AM ++ +F+ GR+M + + S S S +G
Sbjct: 10 IAIVALYFILVM--CIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIG 67
Query: 70 LSGMAYKMG-VTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
L+G G W ++ ++ +V++ I +R T+P+Y RF +
Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRS-----GVYTMPEYLSKRFGG-HR 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I A++ +I+++ + + +GA + +LG +++ ++++ + M + + GG +AV
Sbjct: 122 IQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN--------------- 233
Y D ++A++MI+G + L VI++ ++GG EEV + P + +
Sbjct: 182 IYTDTLQALLMIVGALTLMVISMMEIGGFEEVKRRYMLASPNVTSILLTYNLSNTNSCNV 241
Query: 234 ------------------PWAFGAGVVIGF--LGIGFGSPGQPHIIVRYMSIDDPNKLRV 273
PW G ++G + + Q I+ R ++ + +
Sbjct: 242 HPKKDALKMLRNPTDEDVPW---PGFILGQTPASVWYWCADQV-IVQRVLAAKNIAHAKG 297
Query: 274 STVVGTFWNVVLAWGAIFVGLAGRAIVPD---------VSQLPGKNA---EMIYPYLSAQ 321
ST++ F ++ + + G+ R + D Q+ G A + YP L +
Sbjct: 298 STLMAGFLKLLPMFIIVVPGMISRILFADDIACINPEHCMQVCGSRAGCSNIAYPRLVMK 357
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
P L G+++ + AA++S DS + D+Y+ + K+ + + + + R+
Sbjct: 358 LVPVGLRGLMMAVMIAALMSDLDSIFNSAQAIFTLDVYKLIRKRPS---SRELMIVGRIF 414
Query: 382 V--LVVGFLA--AILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGV 433
V +VV +A I+ + ++ ++ L +L+++WK + +G
Sbjct: 415 VAFMVVISIAEVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGG 474
Query: 434 LAGMIVGTI-TTIVW-------------KLYLKPITGLYELVPAFIFSLIATIIVSMITK 479
+AG I+G + T+ + +++K I +Y F + + T+IVS++T
Sbjct: 475 MAGFILGAVRLTLAFAYRAPECDQPDNRPVFIKDIHYMYVATALFWITGLITVIVSLLTP 534
Query: 480 PP 481
PP
Sbjct: 535 PP 536
>sp|P31637|SL53_CANFA SODIUM/MYO-INOSITOL COTRANSPORTER (NA(+)/MYO-INOSITOL
COTRANSPORTER) >gi|539710|pir||A42163 Na+/myo-inositol
cotransporter - dog
Length = 718
Score = 110 bits (272), Expect = 4e-23
Identities = 112/540 (20%), Positives = 233/540 (42%), Gaps = 83/540 (15%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+A+VA F L++ +GF+AM ++ +F+ GR+M + + S S S +G
Sbjct: 10 IAIVALYFILVM--CIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIG 67
Query: 70 LSGMAYKMG-VTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
L+G G W ++ ++ +V++ I +R T+P+Y RF +
Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRS-----GVYTMPEYLSKRFGG-HR 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I A++ +I+++ + + +GA + +LG +++ ++++ + M + + GG +AV
Sbjct: 122 IQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN--------------- 233
Y D ++A++MI+G + L +I++ ++GG EEV + P + +
Sbjct: 182 IYTDTLQALLMIVGALTLMIISMMEIGGFEEVKRRYMLASPNVTSILLTYNLSNTNSCNV 241
Query: 234 ------------------PWAFGAGVVIGF--LGIGFGSPGQPHIIVRYMSIDDPNKLRV 273
PW G V+G + + Q I+ R ++ + +
Sbjct: 242 HPKKDALKMLRNPTDEDVPW---PGFVLGQTPASVWYWCADQV-IVQRVLAAKNIAHAKG 297
Query: 274 STVVGTFWNVVLAWGAIFVGLAGRAIVPD---------VSQLPGKNA---EMIYPYLSAQ 321
ST++ F ++ + + G+ R + D Q+ G A + YP L +
Sbjct: 298 STLMAGFLKLLPMFIIVVPGMISRILFADDIACINPEHCMQVCGSRAGCSNIAYPRLVMK 357
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
P L G+++ + AA++S DS ++ D+Y ++I++ E + V
Sbjct: 358 LVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVY-KLIRRSASSRELMIVGRIFVA 416
Query: 382 VLVVGFLA--AILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLA 435
+VV +A I+ + ++ ++ L +L+++WK + +G +A
Sbjct: 417 FMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMA 476
Query: 436 GMIVGTITTIVWKLY--------------LKPITGLYELVPAFIFSLIATIIVSMITKPP 481
G ++G + + Y +K I +Y F + + T+IVS++T PP
Sbjct: 477 GFVLGAVRLTLAFAYRAPECDQPDNRPGFIKDIHYMYVATALFWVTGLITVIVSLLTPPP 536
>sp|P53791|SL51_SHEEP SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE COTRANSPORTER 1)
(HIGH AFFINITY SODIUM-GLUCOSE COTRANSPORTER)
>gi|2119800|pir||S59637 glucose transport protein SGLT1,
intestinal - sheep >gi|861071|emb|CAA57808.1| (X82410)
sodium/glucose cotransporter [Ovis aries]
>gi|861073|emb|CAA57809.1| (X82411) sodium/glucose
cotransporter-like protein [Ovis aries]
>gi|2326776|emb|CAA04483.1| (AJ001026) sodium/glucose
symporter-like protein [Ovis aries]
Length = 664
Score = 109 bits (270), Expect = 7e-23
Identities = 118/550 (21%), Positives = 236/550 (42%), Gaps = 83/550 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
AYE ++N + + ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 19 AYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ +V + FV + I+ +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAAAGIATGGFEWNALILVVLLGWVFVPIYIKA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIV 178
RF +I + + +++++ + + A +GA ++ ALG+ ++ A+ I + + +
Sbjct: 132 LRKRFGG-QRIQVYLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITAL 190
Query: 179 YMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGG-TEEVLKVLHAL---------- 227
Y I GG AV Y D ++ VIM++G +L A +VGG + V K ++A+
Sbjct: 191 YTITGGLAAVIYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVTKYMNAIPTVTSYGNTT 250
Query: 228 -----------------DP-KLINPWAFGAGVVIGFLGIGFGSPGQPHIIV-RYMSIDDP 268
DP K PW G++ G I +IV R +S +
Sbjct: 251 VKKECYTPRADSFHIFRDPLKGDLPW---PGLIFGLTIISLWYWCTDQVIVQRCLSAKNM 307
Query: 269 NKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD--VSQLPGK----------NAEMIYP 316
+ ++ ++ + ++ + + G+ R + + +P + + YP
Sbjct: 308 SHVKAGCIMCGYMKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYP 367
Query: 317 YLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALT 376
L + P L G+++ + A+++S+ S ++ D+Y ++ KK + EK +
Sbjct: 368 TLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYTKIRKKAS---EKELMI 424
Query: 377 ISRVTVLV-VGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK-- 430
R+ +LV +G A I+ +F ++ LG +L+++ K +
Sbjct: 425 AGRLFMLVLIGVSIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPG 484
Query: 431 --WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATIIV 474
WG++ G ++G I Y ++P + LY + F+ ++I + +
Sbjct: 485 AFWGLIIGFLIGVSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544
Query: 475 SMITKPPENV 484
S+ TKP +V
Sbjct: 545 SLFTKPIADV 554
>gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgidus]
>gi|7442767|pir||D69400 pantothenate permease (panF-2)
homolog - Archaeoglobus fulgidus
>gi|2649380|gb|AAB90040.1| (AE001021) pantothenate
permease (panF-2) [Archaeoglobus fulgidus]
Length = 474
Score = 109 bits (270), Expect = 7e-23
Identities = 114/471 (24%), Positives = 209/471 (44%), Gaps = 29/471 (6%)
Query: 18 LFTLILPILVGFYAMKRT-KSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYK 76
++ L+ + VGFY MKR KSEED+ V R + + V ++ + + +LG+ AY
Sbjct: 1 MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYD 60
Query: 77 MGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASI 136
+G+ AVW + + + ++ G +++ + +VP++ + F + L + A I
Sbjct: 61 IGLPAVWFSFAHAIMLAIVCLFTG----RWARKLKVESVPEFLDVIFSNYWLRLMVGAVI 116
Query: 137 IIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRA 196
IF + Q +S G SI ++I L+ I+Y++L G VA+ +V+ A
Sbjct: 117 AGAIFGICTLETQ--GLGVFVSILTGTSIEVGIVIGALIGILYVVLSGMKEVAWLNVLNA 174
Query: 197 VIMIIGLVVLP-VIAVAKVGGTEEVLKVLHALD----PKLINPWAFGAG-VVIGFLGIGF 250
VI+ IG++ V+ G E V + + D + W G ++ L F
Sbjct: 175 VILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGSWEVFVGFALVNVLATVF 234
Query: 251 GSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGKN 310
+ ++ P+ LR + ++ N A A +G+A RA P+ ++L K
Sbjct: 235 FQGISQQGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARA-TPEFAELGAKT 293
Query: 311 AEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKID 370
A P + P +L+ A+LS+ LL + V D+Y+ V+K +
Sbjct: 294 AT---PAMIVSVLPTWASALLLATCLVAVLSSYAITLLAPTTIFVNDIYKAVLKPNASHE 350
Query: 371 EKTALTISRVTVLVVGFLAAILAYVAKDII---FWFVLFAWGGLGASFGPTLILSLYWKG 427
E L +SR+ +++ A I A I+ W LF+W L F +I L+WK
Sbjct: 351 E--LLRLSRILTVLLAVAALIPAVSLPPILAAMMW--LFSW--LVPVFW-FVIFGLFWKR 403
Query: 428 TTKWGVLAGMIVGTITTIVWKLY-LKPITGLYELVPAFIFSLIATIIVSMI 477
+ ++ ++V +T W + L + G + +LI T+++ +
Sbjct: 404 SAPAAIITCLLV-WVTINAWTMTPLPEVLGAPGWLHQVYLALIVTLVIGSL 453
>pir||S48858 glucose transport protein homolog - sheep
Length = 664
Score = 108 bits (268), Expect = 1e-22
Identities = 119/550 (21%), Positives = 236/550 (42%), Gaps = 83/550 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
AYE ++N + + ++ + VG +AM T + FF+ GR+M + S +S
Sbjct: 19 AYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ +V + FV + I+ +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAAAGIATGGFEWNALILVVLLGWVFVPIYIKA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIV 178
RF +I + + +++++ + + A +GA ++ ALG+ ++ A+ I + + +
Sbjct: 132 LRKRFGG-QRIQVYLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITAL 190
Query: 179 YMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGG-TEEVLKVLHAL---------- 227
Y I GG AV Y D ++ VIM++G +L A +VGG + V K ++A+
Sbjct: 191 YTITGGLAAVIYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVRKYMNAIPTVTSYGNTT 250
Query: 228 -----------------DP-KLINPWAFGAGVVIGFLGIGFGSPGQPHIIV-RYMSIDDP 268
DP K PW G++ G I +IV R +S +
Sbjct: 251 VKKECYTPRADSFHIFRDPLKGDLPW---PGLIFGLTIISLWYWCTDQVIVQRCLSAKNM 307
Query: 269 NKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD--VSQLPGK----------NAEMIYP 316
+ ++ ++ + ++ + + G+ R + + +P + + YP
Sbjct: 308 SHVKAGCIMCGYMKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYP 367
Query: 317 YLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALT 376
L + P L G+++ + A+++S+ S ++ D+Y ++ KK + EK +
Sbjct: 368 TLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYTKIRKKAS---EKELMI 424
Query: 377 ISRVTVLVV-GFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK-- 430
R+ +LVV G A I+ +F ++ LG +L+++ K +
Sbjct: 425 AGRLFMLVVIGVSIAWVPIVQSAQSGQLFDYIQSITSYLGPPMRAVFLLAIFCKRVNEPG 484
Query: 431 --WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATIIV 474
WG++ G ++G I Y ++P + LY + F+ ++I + +
Sbjct: 485 AFWGLIIGFLIGVSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544
Query: 475 SMITKPPENV 484
S+ TKP +V
Sbjct: 545 SLFTKPIADV 554
>dbj|BAA22950.1| (AB008225) Na+-glucose cotransporter type 1 (SGLT-1)-like protein
[Xenopus laevis]
Length = 673
Score = 108 bits (266), Expect = 2e-22
Identities = 112/535 (20%), Positives = 227/535 (41%), Gaps = 80/535 (14%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+ +V + + + VG +M RTK + + +F+ G+ M V S +S S +G
Sbjct: 26 IDIVVLVLYFVFVLAVGLLSMCRTKRGTVKGYFLAGKDMAWWPVGASLFASNVGSGHFIG 85
Query: 70 LSGMAYKMGVTAV---WAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDT 126
L+G G+ W + ++A + F+ + I T+P+Y + RF
Sbjct: 86 LAGSGAASGIAVTAYEWNGLFCVLALAWLFLPIYISA-------GVTTMPEYLQRRFGG- 137
Query: 127 SKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFI 186
+I A + + I++ + + AGA + AL ++ A++ +++ +Y + GG
Sbjct: 138 KRIQIFLAILYLFIYIFTKISVDMYAGALFIQQALQWDLYVAVIGLLVITAIYTVAGGLA 197
Query: 187 AVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHAL------------------ 227
AV Y D ++ VIMIIG ++L + ++GG E + K HA+
Sbjct: 198 AVIYTDTLQTVIMIIGALILMAYSFIEIGGFEALQEKYFHAIPNTHSGNSTCGIPREDAF 257
Query: 228 ----DPKLIN-PWAFGAGVVIGFL--GIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTF 280
DP + PW GV++G + + Q I+ R +S + + + +++
Sbjct: 258 HIFRDPVTSDLPW---PGVLVGMTIPSLWYWCTDQV-IVQRSLSAKNLSHAKAGSLLAAS 313
Query: 281 WNVVLAWGAIFVGLAGRAIVPD------------VSQLPGKNAEMIYPYLSAQYFPPILY 328
V+ + + G+ R + D + P +++ YP + + P L
Sbjct: 314 LKVLPLFMMVLPGMISRVLFTDQVACADPELCKEICGNPSGCSDIAYPKMVIELLPTGLR 373
Query: 329 GILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFL 388
G+++ + AA++S+ S ++ DL++ + + T E + + RV VLV+ +
Sbjct: 374 GLMMSVMIAALMSSLTSIFNSASTIFTMDLWRHIRPRST---EWELMIVGRVFVLVLVVV 430
Query: 389 AAILAYVAK----DIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLAGMIVG 440
+ + + + +F ++ L I +WK T + WG+ G++VG
Sbjct: 431 SILWIPLVQASQGGQLFIYIQSISSYLQPPVAVVFIAGCFWKRTNEKGAFWGMTIGLVVG 490
Query: 441 TITTIVWKLYLKP--------------ITGLYELVPAFIFSLIATIIVSMITKPP 481
I ++ +Y+ P + LY + + +L+ + VS+ T+PP
Sbjct: 491 LIRMVLDFIYVAPQCDQPDTRPGVVKYVHYLYLSMILGLLTLLVVVAVSLWTEPP 545
>gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgidus]
>gi|7442769|pir||E69279 pantothenate permease (panF-3)
homolog - Archaeoglobus fulgidus
>gi|2650404|gb|AAB90996.1| (AE001089) pantothenate
permease (panF-3) [Archaeoglobus fulgidus]
Length = 461
Score = 108 bits (266), Expect = 2e-22
Identities = 114/483 (23%), Positives = 220/483 (44%), Gaps = 36/483 (7%)
Query: 12 VALVAFLFTLILPILVG----FYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLV 67
V L+ FL+ I I++G AMK +++E++++ GR + + AL+ ++ S++++
Sbjct: 2 VKLIEFLYAFIGYIIIGTAIAIMAMKGLRTQEEYYIAGRKVSGVISALTYAATTYSAFMM 61
Query: 68 LGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTS 127
+GL G++Y GV A+ + Y+V +F Y R+ + ++ +T D R+ S
Sbjct: 62 VGLVGLSYFSGVGALGFELFYLVGTLFLLSYYAPRVWEMAKERGYVTPGDMIAERY--GS 119
Query: 128 KILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIA 187
++ ++ A +I+ I L Y+ Q + LS +S ++ S ++I ++ LGG
Sbjct: 120 EVAKLMA-VIVSIALIPYISVQLIGVSLILSKTNAMSFEAGIVASAILIALWAFLGGLRG 178
Query: 188 VAYNDVIRAVIMIIGLVVLPVIAVAKVGGTE-EVLKVLHALDPKLINPWAFGAGVVIGFL 246
VA+ D ++ V M++ + + ++ V + G E + + L L+ P + V L
Sbjct: 179 VAWTDALQGVFMLL-MAIAAILWVHQYGFAEKDFFTEVSRLGELLVVPNSIWTPVKFISL 237
Query: 247 GIG--FGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAI--VPD 302
+ F + P + R D + LR ++ F+ ++ +GL R + +
Sbjct: 238 TLPWFFFALTNPQVFQRLYIPKDRSALRRMVILFGFFGLIYTVIVTLIGLELRTMTEMGV 297
Query: 303 VSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLY-QE 361
++P ++A + P + A PP+L + IFAA ++TA+S +L ++S + +DL E
Sbjct: 298 FPKVPDRDA--VTPTMLAM-MPPLLGAAISLSIFAAAITTANSIVLTLSSMITRDLLGSE 354
Query: 362 VIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLIL 421
+ G RV ++++ A+ AY I + + L LIL
Sbjct: 355 KVGSG------------RVLIVILTVAVALFAYSRPGYIVELSVLSSTILLCQL--PLIL 400
Query: 422 SLYWKGTTKWGVLAG---MIVGTITTIVWKLYLKPITGLYELVPAFIFSLIATIIVSMIT 478
++ + G LAG + G IT +V + V FI S + +S
Sbjct: 401 GVF--HLNRGGRLAGIATLSAGFITAVVLSFQKLSPLSIPASVWTFIISFAVFLALSSSE 458
Query: 479 KPP 481
K P
Sbjct: 459 KQP 461
>pir||S48857 glucose transport protein - sheep >gi|2148056|pir||S59638 glucose
transport protein SGLT1, parotid gland - sheep
Length = 664
Score = 107 bits (264), Expect = 4e-22
Identities = 117/550 (21%), Positives = 235/550 (42%), Gaps = 83/550 (15%)
Query: 4 AYEMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSG 61
AYE ++N + + ++ + VG + M T + FF+ GR+M + S +S
Sbjct: 19 AYERIRNAADISVIVIYFVVVMAVGLWHMFSTNRGTVGGFFLAGRSMVWWPIGASLFASN 78
Query: 62 RSSWLVLGLSGMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDY 118
S +GL+G G+ W A+ +V + FV + I+ +T+P+Y
Sbjct: 79 IGSGHFVGLAGTGAAAGIATGGFEWNALILVVLLGWVFVPIYIKA-------GVVTMPEY 131
Query: 119 FEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIV 178
RF +I + + +++++ + + A +GA ++ ALG+ ++ A+ I + + +
Sbjct: 132 LRKRFGG-QRIQVYLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITAL 190
Query: 179 YMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGG-TEEVLKVLHAL---------- 227
Y I GG AV Y D ++ VIM++G +L A +VGG + V K ++A+
Sbjct: 191 YTITGGLAAVIYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVTKYMNAIPTVTSYGNTT 250
Query: 228 -----------------DP-KLINPWAFGAGVVIGFLGIGFGSPGQPHIIV-RYMSIDDP 268
DP K PW G++ G I +IV R +S +
Sbjct: 251 VKKECYTPRADSFHIFRDPLKGDLPW---PGLIFGLTIISLWYWCTDQVIVQRCLSAKNM 307
Query: 269 NKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD--VSQLPGK----------NAEMIYP 316
+ ++ ++ + ++ + + G+ R + + +P + + YP
Sbjct: 308 SHVKAGCIMCGYMKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYP 367
Query: 317 YLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALT 376
L + P L G+++ + A+++S+ S ++ D+Y ++ KK + EK +
Sbjct: 368 TLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYTKIRKKAS---EKELMI 424
Query: 377 ISRVTVLV-VGFLAA---ILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK-- 430
R+ +LV +G A I+ +F ++ LG +L+++ K +
Sbjct: 425 AGRLFMLVLIGVSIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPG 484
Query: 431 --WGVLAGMIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATIIV 474
WG++ G ++G I Y ++P + LY + F+ ++I + +
Sbjct: 485 AFWGLIIGFLIGVSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544
Query: 475 SMITKPPENV 484
S+ TKP +V
Sbjct: 545 SLFTKPIADV 554
>gb|AAF54633.1| (AE003691) CG6723 gene product [Drosophila melanogaster]
Length = 587
Score = 107 bits (264), Expect = 4e-22
Identities = 104/398 (26%), Positives = 178/398 (44%), Gaps = 24/398 (6%)
Query: 15 VAFLFTLILPILVGFYA--MKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSG 72
VAF+ +L I +G Y M ++ SE+D+ +GGR M I +A S V+S S +LGL
Sbjct: 20 VAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPT 79
Query: 73 MAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
Y G+ ++ + G I V MG+ N + +Y E RF + LR+
Sbjct: 80 EVYSYGIQYLYVSCGVIGMG----VVMGVFYLPVFHDLNITSTYEYLEVRF---DRRLRL 132
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
S++ I +Y+ A + GI + T I ++ + Y LGG AV + D
Sbjct: 133 YGSVMFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTD 192
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALD----PKL-INPWAFGAGVVIGFLG 247
V++A+ M+ L ++ + +GG VL+ + D P L I+P + F G
Sbjct: 193 VVQAISMLGALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTFWCLFFGG 252
Query: 248 IGFGSPG---QPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVS 304
I + + ++I RY+S+ R + + ++L + GL A +
Sbjct: 253 IVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLIYATYQNCD 312
Query: 305 QLPGKNA---EMIYPYLSAQYFP--PILYGILIGGIFAAILSTADSQLLVVASTVVKDLY 359
L K A + + P + P + G+ I G+F+A LS+ + L +++ V++D
Sbjct: 313 PLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFV 372
Query: 360 QEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAK 397
+ +KK + I R+ V+ VG L L YV +
Sbjct: 373 KPYVKK--PLSSSAINWIMRLVVVGVGVLCVCLVYVVE 408
>sp|P31636|SL54_PIG SODIUM/GLUCOSE COTRANSPORTER 3 (NA(+)/GLUCOSE COTRANSPORTER 3) (LOW
AFFINITY SODIUM-GLUCOSE COTRANSPORTER)
>gi|346476|pir||A44432 amino acid transport protein -
pig >gi|164667|gb|AAC37325.1| (L02900) low-affinity
Na-dependent glucose cotransporter [Sus scrofa]
Length = 660
Score = 103 bits (255), Expect = 4e-21
Identities = 112/543 (20%), Positives = 233/543 (42%), Gaps = 73/543 (13%)
Query: 6 EMLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGRS 63
E ++N + + ++ + VG +AM RT + FF+ GR + + S +S
Sbjct: 21 ERIQNAADISVIVIYFVVVMAVGLWAMLRTNRGTVGGFFLAGRDVTWWPMGASLFASNIG 80
Query: 64 SWLVLGLSGMAYKMGVTAV---WAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFE 120
S +GL+G G+ W A+ ++ + FV + I+ +T+P+Y
Sbjct: 81 SGHFVGLAGTGAASGIAIAAFEWNALLLLLVLGWFFVPIYIKA-------GVMTMPEYLR 133
Query: 121 ARFRDTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVY 179
RF K L+I SI+ + I + + + +GA + ALG+ ++ A+ + + +Y
Sbjct: 134 KRFG--GKRLQIYLSILSLFICVALRISSDIFSGAIFIKLALGLDLYLAIFSLLAITAIY 191
Query: 180 MILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGG----TEEVLKVLH--------AL 227
I GG +V Y D ++ +IM+IG +L A +VGG TE+ + + +
Sbjct: 192 TITGGLASVIYTDTLQTIIMLIGSFILMGFAFVEVGGYESFTEKYMNAIPTIVEGDNLTI 251
Query: 228 DPKLINPWAFGAGVV-------IGFLGIGFGSP--------GQPHIIVRYMSIDDPNKLR 272
PK P + I + G+ FG I+ R +S D + ++
Sbjct: 252 SPKCYTPQGDSFHIFRDAVTGDIPWPGMIFGMTVVAAWYWCTDQVIVQRCLSGKDMSHVK 311
Query: 273 VSTVVGTFWNVVLAWGAIFVGLAGRAIVPD--VSQLPGK----------NAEMIYPYLSA 320
+ ++ + ++ + + G+ R + + +P + + YP L
Sbjct: 312 AACIMCGYLKLLPMFLMVMPGMISRILYTEKVACVVPSECVKHCGTEVGCSNYAYPLLVM 371
Query: 321 QYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRV 380
+ P L G+++ + A+++S+ S ++ DLY ++ K+ ++ + A + +
Sbjct: 372 ELMPSGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYTKIRKQASEKELLIAGRLFII 431
Query: 381 TVLVVGFLAAILAYVAKD-IIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLA 435
++V+ + L VA++ +F ++ LG +L+++ K + WG++
Sbjct: 432 LLIVISIVWVPLVQVAQNGQLFHYIESISSYLGPPIAAVFLLAIFCKRVNEQGAFWGLII 491
Query: 436 GMIVGTITTIVWKLY--------------LKPITGLYELVPAFIFSLIATIIVSMITKPP 481
G ++G I I +Y + + LY + F S++ + +S++TKP
Sbjct: 492 GFVMGLIRMIAEFVYGTGSCLAASNCPQIICGVHYLYFALILFFVSILVVLAISLLTKPI 551
Query: 482 ENV 484
+V
Sbjct: 552 PDV 554
>gi|4507035 solute carrier family 5 (sodium iodide symporter), member 5 [Homo
sapiens] >gi|11526040|ref|XP_009295.1| solute carrier
family 5 (sodium iodide symporter), member 5 [Homo
sapiens] >gi|2136179|pir||JC4974 sodium iodide symporter
- human >gi|1628579|gb|AAB17378.1| (U66088) sodium
iodide symporter [Homo sapiens]
>gi|3702269|gb|AAC62827.1| (AC005796) sodium iodide
symporter [Homo sapiens]
Length = 643
Score = 102 bits (251), Expect = 1e-20
Identities = 104/447 (23%), Positives = 194/447 (43%), Gaps = 37/447 (8%)
Query: 18 LFTLILPILVGF-----YAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSG 72
+F L+L + G A +S EDFF GGR + + V LS +S S+ VLG+
Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPS 78
Query: 73 MAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
AY+ G+ +W +G ++ V + R + +Y E RF S+ +R+
Sbjct: 79 EAYRYGLKFLWMCLG----QLLNSVLTALLFMPVFYRLGLTSTYEYLEMRF---SRAVRL 131
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++ I+ Y G A A L+ G+ I+ +L+ + ++ Y +GG AV + D
Sbjct: 132 CGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTD 191
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLH---ALDPKLINP--------WAFGAGV 241
V + V+M+ G V+ V VGG +VL + ++ NP W F G
Sbjct: 192 VFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGG 251
Query: 242 VIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVP 301
+ +L + + Q + RY++ + +++ ++ ++ A G+
Sbjct: 252 TLVWLSMYGVNQAQ---VQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYT 308
Query: 302 DVSQ-LPGKNA--EMIYPYLSAQYFP--PILYGILIGGIFAAILSTADSQLLVVASTVVK 356
D L G+ + + P L F P + G+ + ++ LSTA + + +A+ V+
Sbjct: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVE 368
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFG 416
DL + ++ + + + IS+ L+ G +A ++ + + ++ +G G
Sbjct: 369 DLIKPRLR---SLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISG 425
Query: 417 PTL---ILSLYWKGTTKWGVLAGMIVG 440
P L IL ++ GVLAG+ G
Sbjct: 426 PLLGAFILGMFLPACNTPGVLAGLGAG 452
>pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1653432|dbj|BAA18346.1| (D90913) sodium-coupled
permease [Synechocystis sp.]
Length = 512
Score = 101 bits (250), Expect = 2e-20
Identities = 103/443 (23%), Positives = 187/443 (41%), Gaps = 38/443 (8%)
Query: 25 ILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWA 84
I +G A ++ + +++F G + + + S +++ S+ +LG G Y G
Sbjct: 17 IAIGAIASRKQDNTDEYFRGAKQIPWWALGFSIIATSFSAASLLGGPGEGYGHGFL---- 72
Query: 85 AVGYIVAEMFQFVYMGIRLRKFSE---RFNAITVPDYFEARFRDTSKILRIAASIIIIIF 141
Y+ ++ + G+ + F R N T +Y E RF ++ L S+ ++F
Sbjct: 73 ---YLQLQLGDLIGYGLVIAVFLPFFVRLNLTTAYEYLERRFDAKTRSL---GSLCFLLF 126
Query: 142 LTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMII 201
+ + +G A A LS GIS TA+++ ++ I+Y + GG AV + DV++ ++ +
Sbjct: 127 VIARLGGLLYAAALVLSVLTGISTNTAILMVGVVSIIYTVAGGITAVVWTDVLQFGMIFV 186
Query: 202 GLVVLPVIAVAKV-GGTEEVLKVL----------HALDPKLIN--PWAFGAGVVIGFLGI 248
GL AV V GG E+ ++ DP I P A A ++ F
Sbjct: 187 GLGAGIWAAVTAVPGGFGELWRIAGENGKLVVFNFDWDPASIRSLPTALIAYGILAFAVA 246
Query: 249 GFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG 308
G + RY+S D R + +G F V+ + +G+ + LPG
Sbjct: 247 GTNQQS----VQRYVSCADEQSARKAIFLGWFSGVLGVGATLLLGVLLFSFYQLQGGLPG 302
Query: 309 K-NAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGT 367
+ I Y PP G L+ IFAA +S+ DS L +A+ + D Y I
Sbjct: 303 NIKPDEILSYFIVNQVPPGASGFLVAAIFAAAMSSIDSALHSLATCMTVDFYDRYI--NI 360
Query: 368 KIDEKTALTISRVTVLVVG----FLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSL 423
+ E ++ +++ ++V G F A A +D++ + V + LG G ++ +
Sbjct: 361 QASEMRSVRVAQGLIIVWGVVAIFSAIYAASTGQDLLEFLVSYTTMFLGPLLG-IFLMGV 419
Query: 424 YWKGTTKWGVLAGMIVGTITTIV 446
+ G G + + I+
Sbjct: 420 LFPRINALGAFYGTVAAVLLVII 442
>emb|CAC00574.1| (AL109659) dJ1024N4.1 (novel Sodium:solute symporter family member
similar to SLC5A1 (SGLT1)) [Homo sapiens]
Length = 552
Score = 101 bits (250), Expect = 2e-20
Identities = 117/531 (22%), Positives = 223/531 (41%), Gaps = 78/531 (14%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
V ++ F+F + + I A + T +F+ GR+M + S +SS S L +GL+
Sbjct: 33 VVVIYFVFVIAVGIWSSIRASRGTIG--GYFLAGRSMSWWPIGASLMSSNVGSGLFIGLA 90
Query: 72 GMAYKMGVTA---VWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
G G+ W A ++A + FV + I +T+P Y + RF +
Sbjct: 91 GTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAA-------GVVTMPQYLKKRFGG-QR 142
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I + + +I+++ + + +GA + ALG +++ + I +++ VY I GG +AV
Sbjct: 143 IQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAV 202
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVG---GTEEVLK-----------VLHALDPKLIN- 233
Y D ++ VIM+ G +VL + VG G E+ + H P +
Sbjct: 203 IYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHI 262
Query: 234 ---------PWAFGAGVVIGFLGIGFGSPGQPHIIV-RYMSIDDPNKLRVSTVVGTFWNV 283
PW G++ G + +IV R +S + + +V+G + +
Sbjct: 263 LRDPVSGDIPW---PGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKI 319
Query: 284 VLAWGAIFVGLAGRAIVPD---------VSQLPGKN---AEMIYPYLSAQYFPPILYGIL 331
+ + + G+ RA+ PD ++ G + + YP L P L G++
Sbjct: 320 LPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLM 379
Query: 332 IGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAI 391
I I AA++S+ S ++ D++Q +K T E+ + + RV V+ + ++ +
Sbjct: 380 IAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKST---EQELMVVGRVFVVFLVVISIL 436
Query: 392 LAYVAKDI----IFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLAGMIVGTIT 443
+ + +F ++ L +L+++ K T+ WG++ G+ VG +
Sbjct: 437 WIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLR 496
Query: 444 TIVWKLYLKPITGLYELVPAFI--------------FSLIATIIVSMITKP 480
I+ Y P G + PA + + I +IVS+ T P
Sbjct: 497 MILEFSYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTP 547
>emb|CAB51758.1| (AL008723) dJ90G24.4 (SAAT1 (low affinity sodium glucose
cotransporter (sodium:solute symporter family))) [Homo
sapiens] >gi|7263938|emb|CAB81772.1| (AJ133127)
sodium-glucose cotransporter [Homo sapiens]
Length = 659
Score = 101 bits (249), Expect = 2e-20
Identities = 118/542 (21%), Positives = 231/542 (41%), Gaps = 75/542 (13%)
Query: 8 LKNPVALVAFLFTLILPILVGFYAMKRTKSEE--DFFVGGRAMDKITVALSAVSSGRSSW 65
++N + + ++ + VG +AM +T FF+ GR M + S +S S
Sbjct: 23 IRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSN 82
Query: 66 LVLGLSGMAYKMGV-TAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+GL+G GV T + ++ + ++++ I ++ +T+P+Y + RF
Sbjct: 83 HYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKS-----GVMTMPEYLKKRFG 137
Query: 125 DTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+ L++ SI+ + I + + A AGA + ALG+ ++ A+ I + M VY G
Sbjct: 138 --GERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTG 195
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLI----------- 232
G +V Y D ++ +IM+IG +L A +VGG E + P ++
Sbjct: 196 GLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASC 255
Query: 233 -NPWAFGAGVV-------IGFLGIGFGSP--------GQPHIIVRYMSIDDPNKLRVSTV 276
P A + I + GI FG P I+ R + D + ++ + +
Sbjct: 256 YTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACI 315
Query: 277 VGTFWNVVLAWGAIFVGLAGRAIVPDV--SQLPGKNAE----------MIYPYLSAQYFP 324
+ + ++ + + G+ R + D+ +P + + YP + + P
Sbjct: 316 MCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMP 375
Query: 325 PILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVL- 383
L G+++ + A+++S+ S ++ DLY ++ K+ + EK L R+ VL
Sbjct: 376 QGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQAS---EKELLIAGRIFVLL 432
Query: 384 --VVGFLAAILAYVAKD-IIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLAG 436
VV + L V+++ + + LG +L+++ K + WG++ G
Sbjct: 433 LTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVG 492
Query: 437 MIVGTITTIVWKLY-----LKP---------ITGLYELVPAFIFSLIATIIVSMITKPPE 482
+ +G I I Y L P + LY + F S++ T+ +S++TKP
Sbjct: 493 LAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIP 552
Query: 483 NV 484
+V
Sbjct: 553 DV 554
>dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens]
Length = 643
Score = 101 bits (249), Expect = 2e-20
Identities = 104/447 (23%), Positives = 194/447 (43%), Gaps = 37/447 (8%)
Query: 18 LFTLILPILVGF-----YAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSG 72
+F L+L + G A +S EDFF GGR + + V LS +S S+ VLG+
Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPS 78
Query: 73 MAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
AY+ G+ +W +G ++ V + R + +Y E RF S+ +R+
Sbjct: 79 EAYRYGLKFLWMCLG----QLLNSVLTPLLFMPVFYRLGLTSTYEYLEMRF---SRAVRL 131
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++ I+ Y G A A L+ G+ I+ +L+ + ++ Y +GG AV + D
Sbjct: 132 CGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTD 191
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLH---ALDPKLINP--------WAFGAGV 241
V + V+M+ G V+ V VGG +VL + ++ NP W F G
Sbjct: 192 VFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGG 251
Query: 242 VIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVP 301
+ +L + + Q + RY++ + +++ ++ ++ A G+
Sbjct: 252 TLVWLSMYGVNQAQ---VQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYT 308
Query: 302 DVSQ-LPGKNA--EMIYPYLSAQYFP--PILYGILIGGIFAAILSTADSQLLVVASTVVK 356
D L G+ + + P L F P + G+ + ++ LSTA + + +A+ V+
Sbjct: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVE 368
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFG 416
DL + ++ + + + IS+ L+ G +A ++ + + ++ +G G
Sbjct: 369 DLIKPRLR---SLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISG 425
Query: 417 PTL---ILSLYWKGTTKWGVLAGMIVG 440
P L IL ++ GVLAG+ G
Sbjct: 426 PLLGAFILGMFLPACNTPGVLAGLGAG 452
>dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacillus halodurans]
Length = 580
Score = 101 bits (249), Expect = 2e-20
Identities = 118/496 (23%), Positives = 212/496 (41%), Gaps = 39/496 (7%)
Query: 12 VALVAFLFTLILPILVGFYAMKRT--KSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+ L +FL I + +Y + T S + +F+GGR++ I +A S + + S+ V+G
Sbjct: 4 IILASFLMYSIFVMWFSWYKTRGTDLSSSDGYFLGGRSLTGIVIASSLILTNLSTEQVVG 63
Query: 70 LSGMAY-KMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARF----R 124
L+G A+ + V W I + FV++ L+ T+PD+ E RF R
Sbjct: 64 LNGQAFGESMVVMAWEVTAPIALILMAFVFLPRYLK-----LGITTIPDFLEQRFDLRTR 118
Query: 125 DTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFT-ALMISVLMIIV---YM 180
+L + + + Y GA +LS+ + IS F L IS+ + I+ Y+
Sbjct: 119 QIVSVLFLLGYATVFLPTVLYSGALVIDSIFSLSSVMDISPFMIVLCISIAIGIISCGYV 178
Query: 181 ILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKV--LHALDPKLIN----- 233
ILGG A A +D I + +IIG +++P++A+ +G + V L + +P +N
Sbjct: 179 ILGGLKACAMSDTINGIGLIIGGLLIPILALFVLGRGDFASGVGELVSANPTKLNAIGND 238
Query: 234 ----PWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGA 289
PWA ++ F + + Q II R ++ + + + + + + A
Sbjct: 239 QASVPWAVLLTGLL-FNNLFYWCTNQS-IIQRTLAAKNLAEGQKGVLFAGMFKIFGAAFL 296
Query: 290 IFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLV 349
+ G+ + DV NA+M YP L P L G L +F AILS+ ++ L
Sbjct: 297 VLPGIIAYLLYGDVLA----NADMAYPSLVIDVMPVALSGFLAAVLFGAILSSFNNVLNS 352
Query: 350 VASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILA---YVAKDIIFWFVLF 406
+ D+Y+ + K K E + R+ + A ++A A +++F+
Sbjct: 353 SITLFTLDIYKPIFKPNAK--EPELVKAGRIFAACLAITAVVIAPFILYAPQGLYYFLQE 410
Query: 407 AWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVPAFIF 466
G +I+ + K + V + K+ L + LY L F
Sbjct: 411 MNGFYSLPIIAMVIVGFFSKYVPASAPKVLVAVHVVLYAGSKVVLGEVNFLYVLSVLFPI 470
Query: 467 SLIATIIVSMITKPPE 482
+++ +IV + KP E
Sbjct: 471 NVLVMLIVGRL-KPRE 485
>gb|AAG01742.1|AF251268_1 (AF251268) low affinity sodium-glucose cotransporter [Mus musculus]
Length = 616
Score = 101 bits (248), Expect = 3e-20
Identities = 118/542 (21%), Positives = 234/542 (42%), Gaps = 74/542 (13%)
Query: 8 LKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGRSSW 65
++N + + I+ + VG +AM R+ + FF+ G M + S +S S
Sbjct: 23 IQNAADISVIVIYFIVVLAVGLWAMVRSNRGTVGGFFLAGHDMAWWPMGASLFASNIGSN 82
Query: 66 LVLGLSGMAYKMGVTAV---WAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEAR 122
+GL+G G+ W A+ ++ + +V++ I ++ +T+P+Y R
Sbjct: 83 HFVGLAGTGAASGIAIAAVEWNAL--LMVLVLGWVFLPIYIKA-----GVMTMPEYLRKR 135
Query: 123 FRDTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMI 181
F K L+I S++ + I + A +GA + ALG++++ A+ I + + Y
Sbjct: 136 FG--GKRLQIYLSVLSLFIMVALQTSAIIFSGAIFIQLALGLNLYLAVFILLAITAFYTA 193
Query: 182 LGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGG----TEEVLKVLHA--------LDP 229
GG +V Y D ++ IM++G ++L A A+VGG TE+ + + + + P
Sbjct: 194 TGGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAIPSVVEGDNLTISP 253
Query: 230 KLINPWAFGAGVV-------IGFLGIGFGSP--------GQPHIIVRYMSIDDPNKLRVS 274
K P V I + G+ FG I+ R + + + ++ +
Sbjct: 254 KCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYWCADQVIVQRCLCGKNMSHVKAA 313
Query: 275 TVVGTFWNVVLAWGAIFVGLAGR---------AIVPDVSQLPGKNA----EMIYPYLSAQ 321
++ + ++ + + G+ R +VP + A YP L +
Sbjct: 314 CILCGYLKLLPMFLMVMPGMISRILYTADKVACVVPSECEKQCGTAVGCTNYAYPTLVLE 373
Query: 322 YFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
P L G+++ + A+++S+ S ++ DLY ++ KK ++ + A I +
Sbjct: 374 LMPEGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRKKASERELMIAGRIFGMV 433
Query: 382 VLVVGFLAAILAYVAKD-IIFWFVLFAWGGLGASFGPTLILSLYWKGTTK----WGVLAG 436
++ V L L V+++ +F ++ LG G +L++++K + WG++ G
Sbjct: 434 LIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRVNEQGAFWGLMVG 493
Query: 437 MIVGTITTIVWKLY-----------LKPITG---LYELVPAFIFSLIATIIVSMITKPPE 482
++VG I I +Y K I G +Y + F S+I + VS +T+P
Sbjct: 494 LVVGLIRLIAEFVYGTGSCVAPSNCPKIICGVHYMYFAIILFFVSIIVILGVSFLTEPIP 553
Query: 483 NV 484
+V
Sbjct: 554 DV 555
>gb|AAG01741.1|AF251267_1 (AF251267) low affinity sodium-glucose cotransporter [Mus musculus]
Length = 656
Score = 100 bits (247), Expect = 4e-20
Identities = 119/549 (21%), Positives = 239/549 (42%), Gaps = 75/549 (13%)
Query: 1 MSNAYEMLKNPVALVAFLFTLILPILVGFYAMKRTKSEE--DFFVGGRAMDKITVALSAV 58
+S+ + N + + ++ + VG +AM +T FF+ GR+M + S
Sbjct: 16 LSSLSNNINNAADISVIVIYFVVVMAVGVWAMLKTNRSTVGGFFLAGRSMTWWPMGASLF 75
Query: 59 SSGRSSWLVLGLSGMAYKMGVTAV-WAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPD 117
+S S +GL+G G+ + + + + + ++++ I ++ +T+P+
Sbjct: 76 ASNIGSGHFVGLAGTGAASGIAVTAFESHSFALLLVLGWIFVPIYIKA-----GVMTMPE 130
Query: 118 YFEARFRDTSKILRIAASIIII-IFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMI 176
Y + RF K L+I SI+ + I + + A +GA + ALG++++ A++I + +
Sbjct: 131 YLKKRFG--GKRLQIYLSILFLFICVILTISADIFSGAIFIKLALGLNLYLAILILLAIT 188
Query: 177 IVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHAL------DP 229
++ I GG +V Y D ++AVIM++G +L V A +VGG E K ++A+ D
Sbjct: 189 AIFTITGGLASVIYTDTVQAVIMLVGSFILMVFAFVEVGGYESFTEKFMNAIPSVVEGDN 248
Query: 230 KLINPWAFG---------AGVVIGFL---GIGFGSP--------GQPHIIVRYMSIDDPN 269
IN + V G + G FG P I+ R + + +
Sbjct: 249 LTINSRCYTPQPDSFHIFRDPVTGDIPWPGTAFGMPITALWYWCINQVIVQRCLCGKNLS 308
Query: 270 KLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDV--SQLPGKNAE----------MIYPY 317
++ + ++ + ++ + + G+ R + D+ +P + + YP
Sbjct: 309 HVKAACILCGYLKLLPLFFMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPM 368
Query: 318 LSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTI 377
L + PP L G+++ + A+++S+ S ++ DLY ++ KK + E+ L
Sbjct: 369 LVLKLMPPGLRGLMLSVMLASLMSSLTSVFNSASTLFTIDLYTKIRKKAS---ERELLIA 425
Query: 378 SR--VTVLVVGFL--AAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK--- 430
R V+VL+V + I+ + + LG +++++ K +
Sbjct: 426 GRLFVSVLIVTSILWVPIVEVSQGGQLVHYTEAISSYLGPPIAAVFLVAVFCKRANEQGA 485
Query: 431 -WGVLAGMIVGTITTIVWKLY-----------LKPITGLYELVPAFIFSLIATII---VS 475
WG++ G+++G I I Y K I G++ L A I + ++ VS
Sbjct: 486 FWGLMVGLVMGLIRMIAEFSYGTGSCLAPSSCPKIICGVHYLYFAIILFFVCILVILGVS 545
Query: 476 MITKPPENV 484
+TKP +V
Sbjct: 546 YLTKPIPDV 554
>pir||G71705 alkaline phosphatase synthesis sensor protein phor (phoR) RP465 -
Rickettsia prowazekii >gi|3861021|emb|CAA14921.1|
(AJ235271) ALKALINE PHOSPHATASE SYNTHESIS SENSOR PROTEIN
PHOR (phoR) [Rickettsia prowazekii]
Length = 921
Score = 100 bits (247), Expect = 4e-20
Identities = 107/490 (21%), Positives = 214/490 (42%), Gaps = 60/490 (12%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSS--GRSSWLVLG 69
+ L+ F L++ +L G +K K+ ++ VG R T+ + +++ G S++L+
Sbjct: 4 IDLLIFTSFLVINLLFGLLNIKNIKNNREYAVGERNFSTGTIVATLIATWIGTSTFLID- 62
Query: 70 LSGMAYKMGVTAVWAAV-GYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
+ + Y G+ + ++ G +V+ + ++ R F +++V + A + +
Sbjct: 63 -NSIIYPDGLFYLLPSIFGSVVSWLLMSYFIAPRFENF---LGSLSVAEIIGAAYGNK-- 116
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
+RI SI+ I+ + QF+ L IS F + +II Y GG +V
Sbjct: 117 -VRILTSIVSILMSIGRIAMQFHVAGLILQLFFNISNFYINLCIATVIISYSAFGGVKSV 175
Query: 189 AYNDVIR-----AVIMIIGLVVLPVIAVAKVGGTEEVLK-------VLHALDPKLINPWA 236
+ + ++ A+I +IG+++ V + + V + H PK W
Sbjct: 176 TFTEAVQFFTYSAIIPVIGIIIWNVFSDPYIVINSNVQNHLIDLQGLFHCTSPKF---W- 231
Query: 237 FGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLR----VSTVVGTFWNVVLAWGAIFV 292
+ I F FG P I R + D ++ ++ V+ W+++ W I +
Sbjct: 232 IALNIFIYFAIPSFG----PSIFQRILMAKDTKQISHTFFIAAVICLCWSILFIW--ITI 285
Query: 293 GLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVAS 352
L + V + ++L +I Y+ + G+++G + A I+++ +S + V A
Sbjct: 286 LLFSQNSVIETNEL---FLRIIKSYIGFK-------GLIVGVVMAMIIASTNSDINVAAV 335
Query: 353 TVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLG 412
T D I +K +L + +T +++G + I++ +D+I F+L L
Sbjct: 336 TFTND-----------IIKKASLHYNYITAIIIGLIGFIISLYTQDLINLFLLLTSIYLP 384
Query: 413 ASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLY-LKPITGLYELVPAFIFSLIAT 471
P ++L +K TTK I T I W+++ L+ + G+Y ++PA I +LI
Sbjct: 385 LITLPLILLIYGFKSTTK-SFFISTIAAIFTIIAWQIFSLRTVLGIYPILPATIVTLIFF 443
Query: 472 IIVSMITKPP 481
+ I K P
Sbjct: 444 LGRHYILKQP 453
>emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa]
Length = 643
Score = 100 bits (246), Expect = 5e-20
Identities = 100/447 (22%), Positives = 193/447 (42%), Gaps = 37/447 (8%)
Query: 18 LFTLILPILVGF-----YAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSG 72
+F L+L + G A +S EDFF GGR + + V LS +S S+ VLG+
Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVPA 78
Query: 73 MAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
AY+ G+ +W +G ++ + + R + Y E RF S+ +R+
Sbjct: 79 EAYRYGLKFLWMCLGQLLNSLLT----ALLFLPVFYRLGLTSTYQYLELRF---SRAVRL 131
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++ ++ Y G A A L+ G+ I+ +L+ + ++ Y +GG AV + D
Sbjct: 132 CGTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWTD 191
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVL--HA--------LDP-KLINPWAFGAGV 241
V + ++M+ G V+ VGG VL++ H+ LDP + W F G
Sbjct: 192 VFQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTFWTFVVGG 251
Query: 242 VIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVP 301
+ +L + + Q + RY++ + +++ ++ ++ A G+ A+
Sbjct: 252 TLVWLSMYGVNQAQ---VQRYVACRTEKQAKLALLINQVGLFLIVSSAAACGIVMFALYV 308
Query: 302 DVSQLPGKN---AEMIYPYLSAQYFP--PILYGILIGGIFAAILSTADSQLLVVASTVVK 356
D L + + P L F P + G+ + ++ LSTA + + +A+ V+
Sbjct: 309 DCDPLLAGHISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVE 368
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFG 416
DL + + + + + IS+ L+ G +A ++ + + ++ +G G
Sbjct: 369 DLIKPRL---PNLAPRRLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISG 425
Query: 417 PTL---ILSLYWKGTTKWGVLAGMIVG 440
P L +L ++ GVL+G+ G
Sbjct: 426 PLLGAFVLGMFLPSCNTSGVLSGLAAG 452
>emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa]
Length = 636
Score = 100 bits (246), Expect = 5e-20
Identities = 100/447 (22%), Positives = 193/447 (42%), Gaps = 37/447 (8%)
Query: 18 LFTLILPILVGF-----YAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSG 72
+F L+L + G A +S EDFF GGR + + V LS +S S+ VLG+
Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVPA 78
Query: 73 MAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
AY+ G+ +W +G ++ + + R + Y E RF S+ +R+
Sbjct: 79 EAYRYGLKFLWMCLGQLLNSLLT----ALLFLPVFYRLGLTSTYQYLELRF---SRAVRL 131
Query: 133 AASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYND 192
++ ++ Y G A A L+ G+ I+ +L+ + ++ Y +GG AV + D
Sbjct: 132 CGTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWTD 191
Query: 193 VIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVL--HA--------LDP-KLINPWAFGAGV 241
V + ++M+ G V+ VGG VL++ H+ LDP + W F G
Sbjct: 192 VFQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTFWTFVVGG 251
Query: 242 VIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVP 301
+ +L + + Q + RY++ + +++ ++ ++ A G+ A+
Sbjct: 252 TLVWLSMYGVNQAQ---VQRYVACRTEKQAKLALLINQVGLFLIVSSAAACGIVMFALYV 308
Query: 302 DVSQLPGKN---AEMIYPYLSAQYFP--PILYGILIGGIFAAILSTADSQLLVVASTVVK 356
D L + + P L F P + G+ + ++ LSTA + + +A+ V+
Sbjct: 309 DCDPLLAGHISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVE 368
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFG 416
DL + + + + + IS+ L+ G +A ++ + + ++ +G G
Sbjct: 369 DLIKPRL---PNLAPRRLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISG 425
Query: 417 PTL---ILSLYWKGTTKWGVLAGMIVG 440
P L +L ++ GVL+G+ G
Sbjct: 426 PLLGAFVLGMFLPSCNTSGVLSGLAAG 452
>gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transporter [Rattus
norvegicus] >gi|3746793|gb|AAC64060.1| (AF081204) sodium
dependent multivitamin transporter [Rattus norvegicus]
>gi|3746795|gb|AAC64061.1| (AF081205) sodium dependent
multivitamin transporter [Rattus norvegicus]
Length = 634
Score = 97.9 bits (240), Expect = 2e-19
Identities = 117/510 (22%), Positives = 203/510 (38%), Gaps = 62/510 (12%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSEE---DFFVGGRAMDKITVALSAVSSGRSSWLVL 68
V V F L+L +++G Y R + + R M + VALS +++ +S+ +L
Sbjct: 26 VDYVVFGLLLVLSLVIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAIL 85
Query: 69 GLSGMAYKMGVTAVWAAVGY-----IVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARF 123
G Y+ G + Y I A +F V+ + L E Y E RF
Sbjct: 86 GGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYE---------YLELRF 136
Query: 124 RDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+K +RI ++ I + Y+G A + L+ G ++ +++ ++ +Y LG
Sbjct: 137 ---NKAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALG 193
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVL--HAL--------DPKLIN 233
G AV + DV + +IM +G +V+ ++ AKVGG V V H L DP + +
Sbjct: 194 GLKAVIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPDPFVRH 253
Query: 234 P-WAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFV 292
W G V L + + Q + RY+S +S V + +
Sbjct: 254 TFWTLAFGGVFMMLSLYGVNQAQ---VQRYLSSHSEKAAVLSCYAVFPCQQVALCMSCLI 310
Query: 293 GLAGRAIVPDVSQLPGKNAEMIYPYLSAQYF-------PPILYGILIGGIFAAILSTADS 345
GL A S P E P YF P L G+ + +F+ LST S
Sbjct: 311 GLVMFAYYKKYSMSP--QQEQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISS 368
Query: 346 QLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI--IFWF 403
+A+ ++DL Q ++ E A+ +SR G + +AYV+ + +
Sbjct: 369 AFNSLATVTMEDLIQPWF---PQLTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQA 425
Query: 404 VLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVW------------KLYL 451
L +G +G L +++ G + G++ G +T W
Sbjct: 426 ALSIFGMVGGPLLGLFCLGMFFPCANPLGAIVGLLTG-LTMAFWIGIGSIVSRMSSAAAS 484
Query: 452 KPITGLYELVPA-FIFSLIATIIVSMITKP 480
P+ G +P+ + + T++ S ++KP
Sbjct: 485 PPLNGSSSFLPSNLTVATVTTLMPSTLSKP 514
>pir||B69833 metabolite permease homolog yhjB - Bacillus subtilis
>gi|2226174|emb|CAA74464.1| (Y14081) hypothetical
protein [Bacillus subtilis] >gi|2633381|emb|CAB12885.1|
(Z99109) similar to metabolite permease [Bacillus
subtilis]
Length = 489
Score = 97.1 bits (238), Expect = 4e-19
Identities = 106/449 (23%), Positives = 204/449 (44%), Gaps = 33/449 (7%)
Query: 13 ALVAFLFTLILPILVGFYAMK-RTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
AL+ L+L I +G A K + + E + VGGR + V L +++ LG S
Sbjct: 4 ALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFLGGS 63
Query: 72 GMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILR 131
G AY G A + +A + + ++ + ++++ ++ D+F ++ S +L
Sbjct: 64 GWAYGKGGPAFYIIAYGCLAYILSY-WLLPAVWTYAKQHKLMSQSDFFTKKYN--SPLLG 120
Query: 132 IAASIIIIIFLTSYVGAQFNA-GAKTLSTALG-ISIFTALMISVLMIIVYMILGGFIAVA 189
I S++ I L Y+ Q G T+ G I+ A+ I + I VY+++ G A
Sbjct: 121 ILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAIWIGAVSITVYVMVSGIHGSA 180
Query: 190 YNDVIRAVIMIIGLVVLPV-IAVAKVGGTEEVLKVLHALDPKLIN--------PWAFGAG 240
+ V++ +++++ ++ L V + + GG +++ + + P + W F +
Sbjct: 181 WISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAW-FSST 239
Query: 241 VVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIV 300
V++ LG PH S ++P R + ++ + +VL + +FVG A V
Sbjct: 240 VLLTALGFYMW----PHTFSASYSAENPKVFRKNAIIMPLYQLVLLF-VLFVGFAAILQV 294
Query: 301 PDVSQLPGKNAEMIYPYLSAQYFPPILYGIL-IGGIFAAILSTADSQLLVVASTV-VKDL 358
PD++ G + ++ LS Q F P GI+ G+ A++ S +L+ AST+ K++
Sbjct: 295 PDLN---GADGDLSLLRLSLQAFDPWFVGIIGAAGLLTALV--PGSMILMSASTLFAKNV 349
Query: 359 YQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPT 418
Y+ + + T E+ +++ V V+ ++ + + I +L + + F
Sbjct: 350 YKVIAPRTT---EQQVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVTQLFPAL 406
Query: 419 LILSLYWKGTTKWGVLAGMI--VGTITTI 445
L L TK G AG+I VG +T I
Sbjct: 407 LFSLLKHNMVTKQGAFAGIIAGVGAVTYI 435
>gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacterium sp. NRC-1]
Length = 482
Score = 95.6 bits (234), Expect = 1e-18
Identities = 105/480 (21%), Positives = 203/480 (41%), Gaps = 30/480 (6%)
Query: 21 LILPILVGFYAMKRT-KSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGV 79
+++ + VG A + T + ED+++ GR + + + ++ S++ +AY G
Sbjct: 1 MVVALAVGLVAYRVTDRDAEDYYLAGRGLGTGVLLFTTFATLLSAFTFFAGPNIAYANGP 60
Query: 80 TAVWAAVGYIVAEMFQFVY--MGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASII 137
+ +G + +F ++ +G R + +T+ + RF S+ LR + +
Sbjct: 61 EWI-LVMGLMDGVLFGLLWYVLGYRQWLLGKANGYVTLGEMLGDRFG--SRGLRGLVAGV 117
Query: 138 IIIFLTSYVGAQFNAGAKTLSTALG--ISIFTALMISVLMIIVYMILGGFIAVAYNDVIR 195
I +L YV Q + L G + + L ++VY+ + G VA+ D ++
Sbjct: 118 SIFWLFPYVMLQQIGAGEALVGLTGGAVPYWAGAGFITLFMVVYVAISGMRGVAWTDTLQ 177
Query: 196 AVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIG-FLGIGFGSPG 254
V M+ V V A++ GT L + + + A+ ++ +GI G
Sbjct: 178 GVFMLGITWVAFVWVAAEIAGTTGGLAGALPAEFRALGGGAYSPQWMLSQAIGIAVGVSM 237
Query: 255 QPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPGKNAEMI 314
P + R+ D L+ + + V+L A +G + LP + E I
Sbjct: 238 FPQVNQRFFVADSKRTLKRTFAIWPLLVVLLFVPAFLMGAWANGV-----GLPLPDGENI 292
Query: 315 YPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTA 374
P L ++Y P +++ G AA++S++DS LL +S +D+Y+ + +
Sbjct: 293 VPILLSEYTPGWFAALVVAGALAAMMSSSDSMLLSGSSYFTRDIYRPFVNADATARRED- 351
Query: 375 LTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVL 434
T+ RV V A + + + A+GG A P + L++YW+ TTK G+
Sbjct: 352 -TLGRVGVAAFAVAAFGGSLLRPGSLLEVGSTAFGGF-AQLAPPVALAMYWRRTTKAGMF 409
Query: 435 AGMIVGTITTIVWKLYLKPIT------------GLYELVPAFIFSLIATIIVSMITKPPE 482
AG ++GT + ++ P+T G + V ++ T+ VS +T P +
Sbjct: 410 AG-VLGTQAFYLATVFGPPVTLAGVPIIASSYFGWFAQVVGLPLGVVLTVGVSAVTAPSD 468
>pir||A82432 sodium/solute symporter VCA0667 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9658084|gb|AAF96568.1| (AE004396)
sodium/solute symporter [Vibrio cholerae]
Length = 513
Score = 94.8 bits (232), Expect = 2e-18
Identities = 103/471 (21%), Positives = 193/471 (40%), Gaps = 49/471 (10%)
Query: 21 LILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVT 80
LIL IL+ ++ +R+ DF GGR T +S +++ S+ +G+ G Y+ G+
Sbjct: 14 LILTILISWFVNQRSIGNTDFSTGGRQFGWFTAGVSILATYISAMTFIGMPGWVYQSGME 73
Query: 81 AVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIII 140
A+ + Y + F V+ R ++ +Y E RF R S++ I+
Sbjct: 74 ALNIHLNYPIVIFFAVVF----FIPVFYRMGFTSIYEYLEHRF---GVYARTINSVVFIL 126
Query: 141 FLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMI 200
G A A L L ISI A++ L Y GG V + D++++ ++I
Sbjct: 127 VQCISSGVILYAIALILIQILPISIVEAIVYITLFTACYTYAGGISTVIWTDMLQSAVLI 186
Query: 201 IGLVVLPVIAVAKVGG----TEEVLKVLHALDPKLINPWAFGAGVVIGFLGIGFGSPGQP 256
G V + V+ + +V G + E L +++ ++ + V + FL
Sbjct: 187 AGSVAIFVLLLLQVDGVHGVSREQLNIINLQFDLGVDTTLWAGVVAVSFL---------- 236
Query: 257 HIIVRYMSIDDPNKLRVSTVVGTFWN-------VVLAWGAIFV----GLAGRAIVPDVSQ 305
+MS+ N+L + + T ++ +GA F+ L G + +
Sbjct: 237 -----HMSVYGTNQLIIQRTLATRCEKTAQKSMLLCGYGAFFIYFFFALLGVLLSIFYQE 291
Query: 306 LPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKK 365
N+ + + P + G++I + AA +ST DS +A+ DLYQ I++
Sbjct: 292 RHFTNSNEVILDFVFHHTNPWVIGLIISALAAAAMSTLDSTYNSMATVATFDLYQRFIRR 351
Query: 366 GTKIDEKTALTISRVTVLVVGF--LAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSL 423
D +++++ G + A+LA + ++ +G G + +L L
Sbjct: 352 NAP-DHHYQAVARKMSLVAAGLVVIPALLAVSNESVLKTIASLTSIFVGIRLG-SFVLGL 409
Query: 424 YWKGTTKWGVLAGMIV-------GTITTIVWKLYLKPITGLYELVPAFIFS 467
+ + GV+AG I+ + I W + PI ++ LV + S
Sbjct: 410 FSNQANEKGVIAGSIISIAAVLGARLMDIAWP-WFAPIGTVFFLVSGVVIS 459
>pir||S68513 thyroid iodide transport protein - rat >gi|1399954|gb|AAB03338.1|
(U60282) thyroid sodium/iodide symporter NIS [Rattus
norvegicus]
Length = 618
Score = 94.0 bits (230), Expect = 3e-18
Identities = 96/430 (22%), Positives = 185/430 (42%), Gaps = 34/430 (7%)
Query: 36 KSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQ 95
+S +DFF GGR + + V LS +S S+ VLG+ A + G+ +W G ++ +
Sbjct: 42 RSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCAGQLLNSLLT 101
Query: 96 -FVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGA 154
F+++ I R + Y E RF S+ +R+ ++ ++ Y G A A
Sbjct: 102 AFLFLPIFYR-----LGLTSTYQYLELRF---SRAVRLCGTLQYLVATMLYTGIVIYAPA 153
Query: 155 KTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKV 214
L+ G+ I+ +L+ + ++ +Y +GG AV + DV + V+M++G V+ V +
Sbjct: 154 LILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVILL 213
Query: 215 GGTEEVLKV--------LHALDP---KLINPWAFGAGVVIGFLGIGFGSPGQPHIIVRYM 263
GG VL + L DP W F G + +L + + Q + RY+
Sbjct: 214 GGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGGTLVWLSMYGVNQAQ---VQRYV 270
Query: 264 SIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQ-LPGKNA--EMIYPYLSA 320
+ K +++ +V ++ A G+ D L G+ + + P L
Sbjct: 271 ACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPDQYMPLLVL 330
Query: 321 QYFP--PILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTIS 378
F P + G+ + ++ LSTA + + +A+ V+DL + + + + + IS
Sbjct: 331 DIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDL---IKPRMPGLAPRKLVFIS 387
Query: 379 RVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTL---ILSLYWKGTTKWGVLA 435
+ + G +A ++ + + ++ +G GP L L + GVL+
Sbjct: 388 KGLSFIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLS 447
Query: 436 GMIVGTITTI 445
G+ G ++
Sbjct: 448 GLAAGLAVSL 457
>emb|CAA04650.1| (AJ001290) sodium myo-inositol transporter [Rattus norvegicus]
Length = 385
Score = 94.0 bits (230), Expect = 3e-18
Identities = 57/212 (26%), Positives = 112/212 (51%), Gaps = 11/212 (5%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSE--EDFFVGGRAMDKITVALSAVSSGRSSWLVLG 69
+A+VA F L+ + +GF+AM ++ +F+ GR+M + + S S S +G
Sbjct: 10 IAIVALYFVLV--VCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIG 67
Query: 70 LSGMAYKMG-VTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSK 128
L G G W ++ ++ +V++ I +R T+P+Y RF +
Sbjct: 68 LVGTGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRS-----GVYTMPEYLSKRFGG-HR 121
Query: 129 ILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAV 188
I A++ +++++ + + +GA + +LG +++ ++++ + M + + GG +AV
Sbjct: 122 IQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAV 181
Query: 189 AYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEV 220
Y D ++A++MIIG + L VI++ KVGG EEV
Sbjct: 182 IYTDTLQALLMIIGALTLMVISMMKVGGFEEV 213
>pir||A71662 sodium/pantothenate symporter (panF) RP571 - Rickettsia prowazekii
>gi|3861119|emb|CAA15019.1| (AJ235272)
SODIUM/PANTOTHENATE SYMPORTER (panF) [Rickettsia
prowazekii]
Length = 461
Score = 93.6 bits (229), Expect = 5e-18
Identities = 75/372 (20%), Positives = 168/372 (45%), Gaps = 29/372 (7%)
Query: 107 SERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIF 166
++ + A ++ D + +T + + +++I+ + ++ AQ + LGI
Sbjct: 100 AKHYGAESIGDIMSRYYGNTGRFICGISTVIVSV---GFLAAQISVSGYIFKYILGIHYV 156
Query: 167 TALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHA 226
+++S ++++Y +GG ++ + ++++ MII + + I++ K+G + +
Sbjct: 157 NGVVLSYSIVLIYTTIGGLQSIIFTNLLQFFAMIIAIPTITFISLNKIGVVYFIDNFTNT 216
Query: 227 -LDPKLINPWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNK----LRVSTVVGTFW 281
D + A + + + P I R + +P + V + + F+
Sbjct: 217 NFDQNNRLYYTITAALNFSVMNL------YPTFIQRALINKNPTHTTKAIYVKSAIYFFF 270
Query: 282 NVVLAWGAIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILS 341
+ + + P + + ++ PYL Q PP++ G +I G+ AA++S
Sbjct: 271 LICITLNGLIA----------FKLYPNQPSNLVLPYLINQIIPPVMQGFVISGLLAAVMS 320
Query: 342 TADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIF 401
TADS L V + ++VKD+ ++K ++K L I R+ +++G A I+A ++I
Sbjct: 321 TADSDLNVTSISIVKDIINPIVKVK---NQKKLLLIVRIINVIIGSFAIIVALKFSNVID 377
Query: 402 WFVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELV 461
V+F G G LI +L+ T+K ++ G T + W+ Y + + L
Sbjct: 378 -LVMFFTGFWGPVILVPLITTLFDIRTSKIIIVLSSFSGATTFLTWEYYSFSLQ-YFNLR 435
Query: 462 PAFIFSLIATII 473
F+ ++++ +I
Sbjct: 436 GVFVGTIMSLVI 447
>prf||2204393A Na/I symporter [Rattus norvegicus]
Length = 618
Score = 92.8 bits (227), Expect = 8e-18
Identities = 96/430 (22%), Positives = 184/430 (42%), Gaps = 34/430 (7%)
Query: 36 KSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQ 95
+S +DFF GGR + + V LS +S S+ VLG+ A + G+ +W G ++ +
Sbjct: 42 RSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCAGQLLNSLLT 101
Query: 96 -FVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGA 154
F+++ I R + Y E RF S+ +R+ ++ ++ Y G A A
Sbjct: 102 AFLFLPIFYR-----LGLTSTYQYLELRF---SRAVRLCGTLQYLVATMLYTGIVIYAPA 153
Query: 155 KTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKV 214
L+ G+ I+ +L+ + ++ +Y +GG AV + DV + V+M++G V+ V +
Sbjct: 154 LILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVILL 213
Query: 215 GGTEEVLKV--------LHALDP---KLINPWAFGAGVVIGFLGIGFGSPGQPHIIVRYM 263
GG VL + L DP W F G + +L + + Q + RY+
Sbjct: 214 GGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFYVGGTLVWLSMYGVNQAQ---VQRYV 270
Query: 264 SIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQ-LPGKNA--EMIYPYLSA 320
+ K +++ +V ++ A G+ D L G+ + + P L
Sbjct: 271 ACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPDQYMPLLVL 330
Query: 321 QYFP--PILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTIS 378
F P + G+ + + LSTA + + +A+ V+DL + + + + + IS
Sbjct: 331 DIFEDLPGVPGLFLACAVSGTLSTASTSINAMAAVTVEDL---IKPRMPGLAPRKLVFIS 387
Query: 379 RVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTL---ILSLYWKGTTKWGVLA 435
+ + G +A ++ + + ++ +G GP L L + GVL+
Sbjct: 388 KGLSFIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLS 447
Query: 436 GMIVGTITTI 445
G+ G ++
Sbjct: 448 GLAAGLAVSL 457
>pir||C69903 proline permease homolog yodF - Bacillus subtilis
>gi|2415386|gb|AAB72054.1| (AF015775) permease [Bacillus
subtilis] >gi|2634350|emb|CAB13849.1| (Z99114) similar
to proline permease [Bacillus subtilis]
Length = 496
Score = 92.4 bits (226), Expect = 1e-17
Identities = 109/488 (22%), Positives = 205/488 (41%), Gaps = 41/488 (8%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTKSE---EDFFVGGRAMDKITVALSAVSSGRS 63
M N AL+ ++ + +GF A + S E++ VGGR + V + +
Sbjct: 1 MQGNLTALLITAIIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRRFGGLLVWFLVGADLYT 60
Query: 64 SWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARF 123
++ LGL+ A+ G A +A + Y V F + +L K ++ T+ DY RF
Sbjct: 61 AYTFLGLTSTAFTGGSVAFFA-IPYSVLAYFIAYFFLPKLWKVAKIHKLTTLADYARERF 119
Query: 124 RDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALG--ISIFTALMISVLMIIVYMI 181
SK+L +I+ ++ L Y+ Q + TL A I++ ++IS +++ +Y
Sbjct: 120 N--SKLLASLVAIVGVLMLIPYICLQLSGIQDTLQVAGTGYINVKFVVIISFILVALYTF 177
Query: 182 LGGFIAVAYNDVIRA----VIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN---- 233
G Y +I+ VIM+ +V LP+I G ++ L P+++
Sbjct: 178 FSGIKGPTYTAIIKDILVWVIMLFMVVSLPLI---HFNGWTPMIDTLVKEAPQMLTIPSE 234
Query: 234 -----PWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWG 288
PW A +V + H + + +R +++ +N+VL
Sbjct: 235 GPKGIPWFITASIVSALALFMWA-----HAATGVFTAKSADAVRKNSMFLPLYNIVLIL- 288
Query: 289 AIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLL 348
IF+G ++P+ + N + +L + + G I A L +
Sbjct: 289 VIFLGFIAFLVLPEDT-----NPRLALLHLIQTSYGGVAQGFAYATIALASLIPCSIMAI 343
Query: 349 VVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAW 408
++ +LY+++I + T +T S V V V+G LA + + + L
Sbjct: 344 GASNLFANNLYRDLIHPNVSQSKLTLVTRSMVFV-VIG-LALLFGMLFPTALVTLQLLGV 401
Query: 409 GGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYL-KPITGLYELVPAFIFS 467
G+ F P + +SL+WK TK + G++ G T + +Y+ + G+YE +
Sbjct: 402 SGMVQIF-PAIAVSLFWKNQTKEATVIGLLAGLAVTFI--VYITQSAHGIYEGFWGLAAN 458
Query: 468 LIATIIVS 475
+IA +I++
Sbjct: 459 MIAVVILN 466
>gb|AAF57489.1| (AE003792) CG10444 gene product [Drosophila melanogaster]
Length = 545
Score = 91.7 bits (224), Expect = 2e-17
Identities = 104/439 (23%), Positives = 192/439 (43%), Gaps = 70/439 (15%)
Query: 46 RAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAE---MFQFVYMGIR 102
++M V+ S ++S S+ ++G+S +Y+ G + Y+++ + F+ + R
Sbjct: 4 QSMTTFPVSFSLMASFMSAISLMGVSNESYEFGTIFCVINIAYVLSTPIAAYFFLPVFYR 63
Query: 103 LRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALG 162
+R S V +Y E RF + R++AS+ + + Y+G A A L G
Sbjct: 64 MRTTS-------VYEYLERRFGQAT---RLSASLAFTVQMVLYMGIALYAPALALEAVTG 113
Query: 163 ISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLK 222
I A+++ L+ Y LGG AV DV ++ +M + + ++ K GG +
Sbjct: 114 IHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLMFAAIYAVIAVSAIKAGGFAAIWD 173
Query: 223 VL----------HALDPKLINPWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLR 272
V +LDP + + W ++IG + V Y+S+ N+ +
Sbjct: 174 VAVERGRVNFIEFSLDPTVRHTW---WSLIIGGM-------------VTYLSLYGVNQTQ 217
Query: 273 VSTVVGT----------FWNV----VLAWGAIFVGLAGRAIVPDVSQ-LPGK--NAEMIY 315
V ++ +WN+ +L++ IF GL+ D L G+ + I
Sbjct: 218 VQRLLSVRNLKSAQSALWWNLPILGMLSFSTIFSGLSIFYYYRDCDPLLKGRIDKRDQIM 277
Query: 316 PYLS----AQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKD----LYQEVIKKGT 367
P + QY P L G+ + GIF+A LST S + +++ ++D LY+ + K+ T
Sbjct: 278 PLFALETMGQY--PGLCGLFVSGIFSASLSTISSAVTSLSAVTLEDYLKPLYKAIFKR-T 334
Query: 368 KIDEKTALTISRVTVLVVGFLAAILAYVAKDI--IFWFVLFAWGGLGASFGPTLILSLYW 425
ID K+ + +++ + G L LA+VA + + L +G +G L +
Sbjct: 335 LIDSKSTMP-TKIVACIFGLLCIGLAFVAGSMGGVLQASLTIFGVVGGPLLAIFTLGVCT 393
Query: 426 KGTTKWGVLAGMIVGTITT 444
+ + GVL G +V I +
Sbjct: 394 TRSNQRGVLLGFLVSLIVS 412
>gb|AAB81169.1| (AF006665) YolC [Bacillus subtilis]
Length = 496
Score = 90.9 bits (222), Expect = 3e-17
Identities = 108/488 (22%), Positives = 204/488 (41%), Gaps = 41/488 (8%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTKSE---EDFFVGGRAMDKITVALSAVSSGRS 63
M N AL+ ++ + +GF A + S E++ VGGR + V + +
Sbjct: 1 MQGNLTALLITAIIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRRFGGLLVWFLVGADLYT 60
Query: 64 SWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARF 123
++ LGL+ + G A +A + Y V F + +L K ++ T+ DY RF
Sbjct: 61 AYTFLGLTSTTFTGGSVAFFA-IPYSVLAYFIAYFFLPKLWKVAKIHKLTTLADYARERF 119
Query: 124 RDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALG--ISIFTALMISVLMIIVYMI 181
SK+L +I+ ++ L Y+ Q + TL A I++ ++IS +++ +Y
Sbjct: 120 N--SKLLASLVAIVGVLMLIPYICLQLSGIQDTLQVAGTGYINVKFVVIISFILVALYTF 177
Query: 182 LGGFIAVAYNDVIRA----VIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLIN---- 233
G Y +I+ VIM+ +V LP+I G ++ L P+++
Sbjct: 178 FSGIKGPTYTAIIKDILVWVIMLFMVVSLPLI---HFNGWTPMIDTLVKEAPQMLTIPSE 234
Query: 234 -----PWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWG 288
PW A +V + H + + +R +++ +N+VL
Sbjct: 235 GPKGIPWFITASIVSALALFMWA-----HAATGVFTAKSADAVRKNSMFLPLYNIVLIL- 288
Query: 289 AIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLL 348
IF+G ++P+ + N + +L + + G I A L +
Sbjct: 289 VIFLGFIAFLVLPEDT-----NPRLALLHLIQTSYGGVAQGFAYATIALASLIPCSIMAI 343
Query: 349 VVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAW 408
++ +LY+++I + T +T S V V V+G LA + + + L
Sbjct: 344 GASNLFANNLYRDLIHPNVSQSKLTLVTRSMVFV-VIG-LALLFGMLFPTALVTLQLLGV 401
Query: 409 GGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYL-KPITGLYELVPAFIFS 467
G+ F P + +SL+WK TK + G++ G T + +Y+ + G+YE +
Sbjct: 402 SGMVQIF-PAIAVSLFWKNQTKEATVIGLLAGLAVTFI--VYITQSAHGIYEGFWGLAAN 458
Query: 468 LIATIIVS 475
+IA +I++
Sbjct: 459 MIAVVILN 466
>gb|AAK42614.1| Metabolite permease, putative [Sulfolobus solfataricus]
Length = 505
Score = 89.3 bits (218), Expect = 9e-17
Identities = 109/491 (22%), Positives = 197/491 (39%), Gaps = 42/491 (8%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFF----VGGRAMDKITVALSAVSSGRSSWLVLG 69
++ F+ I+ I +GFY K D + GR + + V + +++ +
Sbjct: 7 IIVFIALFIVFIFLGFYGAFWRKGNLDLLHEWGLAGRRLGTVLVWFLMGADLYTAYTFIA 66
Query: 70 LSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKI 129
+ Y G +A V Y+ + +L S +T D+ + RF S I
Sbjct: 67 VPSSLYAKGAIYFFA-VPYVSLTFAIAMLTMPKLWIVSRNRGYVTAADFVKDRFN--SSI 123
Query: 130 LRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMIL------- 182
L ++ ++ Y+ Q G K++ + + I A ++S + +IV I+
Sbjct: 124 LAALIALTGVVAELPYIALQI-VGMKSVLQMMLLGIGNATLVSEISLIVSFIILAAFTYT 182
Query: 183 GGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKL----------I 232
G A V + +++ I ++ + VI + GG V+++ + I
Sbjct: 183 SGLRGAALTGVFKDILIWITVISVIVIVPLQYGGFTHAFSVINSANLSARYTTLPSNLQI 242
Query: 233 NPWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFV 292
W+ FLG PH I +S DD N+L ST + + + LA A+F
Sbjct: 243 AYWSL-------FLGSALALYLYPHSINGSLSADDKNRLMYSTALLPIYGIGLAIIALF- 294
Query: 293 GLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVAS 352
G+ A+ +S + ++ P L P GI++ GIF L A + ++
Sbjct: 295 GILVYAVPNALSVVSKYGGALVVPALITSTMPDWAAGIMLLGIFVGGLVPAAIMAIAASN 354
Query: 353 TVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLG 412
+V+++ +EV I K T+++ V+ FLA ++ + G L
Sbjct: 355 LLVRNVIKEV---NPSITPKGETTLAKWISAVIKFLALAFVFLVPSTYAINLQLLGGILI 411
Query: 413 ASFGPTLILSLYWKGTTKWGVLAGMIVGTI--TTIVWKLYLKPITGLYE----LVPAFIF 466
P + L LY K W + AG G I T + + L T LY L+ A +
Sbjct: 412 TQTLPAVFLGLYTKWFNPWALTAGWTTGIISGTYMFFTFGLPRATSLYPTLFGLMYAAVI 471
Query: 467 SLIATIIVSMI 477
+L+ ++VS+I
Sbjct: 472 ALVLNLVVSVI 482
>pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (strain K1)
>gi|5104641|dbj|BAA79956.1| (AP000060) 460aa long
hypothetical protein [Aeropyrum pernix]
Length = 460
Score = 89.3 bits (218), Expect = 9e-17
Identities = 98/444 (22%), Positives = 192/444 (43%), Gaps = 33/444 (7%)
Query: 36 KSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQ 95
+ E +F++ GR + A++ ++ SS++++GL G+AY G+ ++ + Y+VA +
Sbjct: 3 RGEGEFYLAGRRLTGFLSAMTYAATTYSSFMIVGLVGLAYFTGIGSLVFELAYLVATVIL 62
Query: 96 FVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAK 155
R+ + S ++ + S + + AS++ ++ L Y AQ A+
Sbjct: 63 LSLFSRRVWRMSRERGWVSPGEMLADLL--GSPWVALTASLVFLVSLVPYASAQLKGIAE 120
Query: 156 TLSTALGIS------IFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVI 209
T+ G S A+ +++L+++ + +L G V D + + M+ +L +
Sbjct: 121 TIVAIAGYSPGDNTAYMVAVGVALLILLAWSLLAGVRGVVLTDAFQGLWMLTAGSLLFLW 180
Query: 210 AVAKVGGTEEVLKVLHALDPK-LINPWAFGAGVVIGFLGIG-FGSPGQPHIIVRYMSIDD 267
++V +VL A++ L + W+ A ++IGF+ F + P ++ R D
Sbjct: 181 LASRVFSKSGASEVLSAMESAGLFDMWS--ATLLIGFVTPWVFFAVTNPQVVQRLYMPKD 238
Query: 268 PNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVP-DVSQLPGKNAEMIYPYLSAQYFPPI 326
LR + + + + +G RA V + + + + + P L P+
Sbjct: 239 EESLRRMILYFFLFGLYYTVLVVAIGFLARAGVELGILSIEPQGRDQVTPQL-LSLAHPL 297
Query: 327 LYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTI-----SRVT 381
L ++ I AA +STADS +L +AS+ +D+ V+ ++DEK L + + T
Sbjct: 298 LAALVFTSIVAASVSTADSIILALASSASRDIGLLVL----RLDEKGRLRLGYAAAALFT 353
Query: 382 VLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVL--AGMIV 439
VL+ F A + Y+ + + V+ P I + W G L A +
Sbjct: 354 VLMAVFAATRIGYIVQLSVLSSVML------LGLAPVTIAA--WVGLRVHPALAVASIAT 405
Query: 440 GTITTIVWKLYLKPITGLYELVPA 463
G + LY + G L PA
Sbjct: 406 GPVLVAANVLYSLAVGGEVSLSPA 429
>gb|AAD37480.1|AF080067_1 (AF080067) sodium-dependent multi-vitamin transporter [Oryctolagus
cuniculus]
Length = 636
Score = 88.5 bits (216), Expect = 2e-16
Identities = 103/459 (22%), Positives = 188/459 (40%), Gaps = 48/459 (10%)
Query: 12 VALVAFLFTLILPILVGFYAMKRTKSEE---DFFVGGRAMDKITVALSAVSSGRSSWLVL 68
V V F L+ + +G Y R + + R M + VALS +++ +S+ +L
Sbjct: 27 VDYVVFSLLLVFSLAIGLYHACRGWGKHTVGQLLLADRRMGCLPVALSLLATFQSAVAIL 86
Query: 69 GLSGMAYKMGVTAVWAAVGY-----IVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARF 123
G+ Y+ G + Y I A +F V+ + L E Y E RF
Sbjct: 87 GVPSEIYRFGTQYWFLGCCYFLGLLIPAHVFIPVFYRLHLTSAYE---------YLELRF 137
Query: 124 RDTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+K++RI ++ I + Y+G A + L+ G ++ +++ ++ +Y LG
Sbjct: 138 ---NKVVRICGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLTLGIVCTIYTALG 194
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVL--HAL--------DPKLIN 233
G AV + DV + ++M +G + + ++ AKVGG V V H L DP + +
Sbjct: 195 GLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWDVASQHGLISGIELDPDPFVRH 254
Query: 234 P-WAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTF--WNVVLAWGAI 290
W G V L + + Q + RY+S K V + F V L+ G +
Sbjct: 255 TFWTLAFGGVFMMLSLYGVNQAQ---VQRYLS-SRTEKAAVLSCYAVFPCQQVALSMGCL 310
Query: 291 FVGLAGRAIVPDV-----SQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADS 345
+GL A + + ++Y + P L G+ + +F+ LST S
Sbjct: 311 -IGLVMFAYYQEYPMSTQQSQAASDQFVLYFVMDLLKGLPGLPGLFVACLFSGSLSTISS 369
Query: 346 QLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI--IFWF 403
+A+ ++DL + + E A+ +SR G L +AY++ + +
Sbjct: 370 AFNSLATVTMEDLIRPWF---PECSEAQAIMLSRSLAFGYGLLCLGMAYISSQMGPVLQA 426
Query: 404 VLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTI 442
+ +G +G L +++ G + G++ G I
Sbjct: 427 AISIFGMVGGPLLGLFCLGMFFPCANPPGAIVGLLAGLI 465
>sp|P31448|YIDK_ECOLI HYPOTHETICAL 62.1 KD PROTEIN IN EMRD-GLVG INTERGENIC REGION
>gi|7430324|pir||H65169 probable transport protein yidK
- Escherichia coli (strain K-12)
>gi|290528|gb|AAA62031.1| (L10328) similar to glucose
transport proteins [Escherichia coli]
>gi|1790113|gb|AAC76702.1| (AE000445) putative
cotransporter [Escherichia coli K12]
Length = 571
Score = 88.5 bits (216), Expect = 2e-16
Identities = 103/496 (20%), Positives = 216/496 (42%), Gaps = 44/496 (8%)
Query: 10 NPVALVAFL-FTLILPILVGFYAMKR-TKSEEDFFVGGRAMDKITVALSAVSSGRSSWLV 67
N + +++F+ FTL++ ++ + K T S++ +F+ GR++ +A S + + S+ +
Sbjct: 2 NSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQL 61
Query: 68 LGLSGMAYKMGVTAV-WAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDT 126
+GLSG AYK G++ + W + +++ L++ T+PD+ E R+ T
Sbjct: 62 VGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKR-----GIATIPDFLEERYDKT 116
Query: 127 SKIL----RIAASIIIIIFLTSYVGA-----QFNAGAKTLSTALGISIFTALMISVLMII 177
++I+ + A+ + + + Y GA F+ G ++L + G +I+ +++ L I
Sbjct: 117 TRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVG-ESLQISHGAAIWLLVILLGLAGI 175
Query: 178 VYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTE-----EVLKVLHALDPKLI 232
+Y ++GG A+A D I + ++IG +++PV + +G E L +HA I
Sbjct: 176 LYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFMQGIEQLTTVHAEKLNSI 235
Query: 233 ----NPWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWG 288
+P GA L F I+ R ++ + + ++ ++
Sbjct: 236 GGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLAEGQKGALLTAVLKMLDPLV 295
Query: 289 AIFVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLL 348
+ GL + D+ + A+M YP L P + G +F A++ST + L
Sbjct: 296 LVLPGLIAFHLYQDLPK-----ADMAYPTLVNNVLPVPMVGFFGAVLFGAVISTFNGFLN 350
Query: 349 VVASTVVKDLYQEVIKKGTK------IDEKTALTISRVTVLVVGFLAAILAYVAKDIIFW 402
++ +Y+ +I + + + K I+ V+VLV ++A A ++
Sbjct: 351 SASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLVAPWIAN-----APQGLYS 405
Query: 403 FVLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLK-PITGLYELV 461
++ G +I+ ++ M +G I+ I +K LY L
Sbjct: 406 WMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITINYLVKFDFHFLYVLA 465
Query: 462 PAFIFSLIATIIVSMI 477
F +++ +++ I
Sbjct: 466 CTFCINVVVMLVIGFI 481
>gi|10863879 solute carrier family 5 (sodium-dependent vitamin transporter),
member 6 [Homo sapiens]
>gi|4884550|gb|AAD31727.1|AF069307_1 (AF069307)
sodium-dependent multivitamin transporter [Homo sapiens]
>gi|5006365|gb|AAD37481.1|AF081571_1 (AF081571)
sodium-dependent multi-vitamin transporter [Homo
sapiens] >gi|5006439|gb|AAD37502.1| (AF116241)
sodium-dependent multivitamin transporter [Homo sapiens]
Length = 635
Score = 88.2 bits (215), Expect = 2e-16
Identities = 103/455 (22%), Positives = 186/455 (40%), Gaps = 46/455 (10%)
Query: 15 VAFLFTLILPILVGFYAMKRTKSEE---DFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
V F+ L+L + +G Y R + + R M + VALS +++ +S+ +LG+
Sbjct: 30 VVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGVP 89
Query: 72 GMAYKMGVTAVWAAVGY-----IVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDT 126
Y+ G + Y I A +F V+ + L E Y E RF
Sbjct: 90 SEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE---------YLELRF--- 137
Query: 127 SKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFI 186
+K +R+ ++ I + Y+G A + L+ G ++ +++ ++ VY LGG
Sbjct: 138 NKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLK 197
Query: 187 AVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVL--------HALDPKLI---NPW 235
AV + DV + ++M +G + + ++ AKVGG V V LDP W
Sbjct: 198 AVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFW 257
Query: 236 AFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVST-VVGTFWNVVLAWGAIFVGL 294
G V L + + Q + RY+S +S V F V L G + +GL
Sbjct: 258 TLAFGGVFMMLSLYGVNQAQ---VQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCL-IGL 313
Query: 295 AGRAIVPD----VSQLPGKNAE-MIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLV 349
A + + Q + ++Y + P L G+ I +F+ LST S
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 350 VASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI--IFWFVLFA 407
+A+ ++DL + + E A+ +SR G L +AY++ + + +
Sbjct: 374 LATVTMEDLIRPWF---PEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISI 430
Query: 408 WGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTI 442
+G +G L +++ G + G++ G +
Sbjct: 431 FGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLV 465
>gi|11429441 solute carrier family 5 (sodium-dependent vitamin transporter),
member 6 [Homo sapiens]
Length = 635
Score = 88.2 bits (215), Expect = 2e-16
Identities = 103/455 (22%), Positives = 186/455 (40%), Gaps = 46/455 (10%)
Query: 15 VAFLFTLILPILVGFYAMKRTKSEE---DFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
V F+ L+L + +G Y R + + R M + VALS +++ +S+ +LG+
Sbjct: 30 VVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGVP 89
Query: 72 GMAYKMGVTAVWAAVGY-----IVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDT 126
Y+ G + Y I A +F V+ + L E Y E RF
Sbjct: 90 SEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE---------YLELRF--- 137
Query: 127 SKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFI 186
+K +R+ ++ I + Y+G A + L+ G ++ +++ ++ VY LGG
Sbjct: 138 NKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLK 197
Query: 187 AVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVL--------HALDPKLI---NPW 235
AV + DV + ++M +G + + ++ AKVGG V V LDP W
Sbjct: 198 AVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFW 257
Query: 236 AFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVST-VVGTFWNVVLAWGAIFVGL 294
G V L + + Q + RY+S +S V F V L G + +GL
Sbjct: 258 TLAFGGVFMMLSLYGVNQAQ---VQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCL-IGL 313
Query: 295 AGRAIVPD----VSQLPGKNAE-MIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLV 349
A + + Q + ++Y + P L G+ I +F+ LST S
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 350 VASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI--IFWFVLFA 407
+A+ ++DL + + E A+ +SR G L +AY++ + + +
Sbjct: 374 LATVTMEDLIRPWF---PEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISI 430
Query: 408 WGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTI 442
+G +G L +++ G + G++ G +
Sbjct: 431 FGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLV 465
>sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)
>gi|443996|emb|CAA52889.1| (X74934) proline permease
[Klebsiella pneumoniae]
Length = 160
Score = 83.9 bits (204), Expect = 4e-15
Identities = 42/113 (37%), Positives = 65/113 (57%), Gaps = 1/113 (0%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV F+ + +L+GF A + TK+ +D+ +GGR++ ALSA +S S WL++GL G
Sbjct: 8 LVTFIVYIFGMVLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGA 67
Query: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSE-RFNAITVPDYFEARFRD 125
+ G++ W A+G + + + RLR +E NA+T PDYF RF D
Sbjct: 68 IFISGISESWIAIGLTLGAWINWKLVAGRLRVHTEVNNNALTXPDYFTGRFED 120
>gb|AAF52616.1| (AE003620) CG8451 gene product [Drosophila melanogaster]
Length = 568
Score = 83.1 bits (202), Expect = 7e-15
Identities = 98/429 (22%), Positives = 183/429 (41%), Gaps = 39/429 (9%)
Query: 40 DFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTAVWAAVGYIVAEM-FQFVY 98
++ +G R + VA+S ++S S +LG + Y G + A+ ++ + +VY
Sbjct: 64 EYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVY 123
Query: 99 MGIRLRKFSERFNAITVP---DYFEARFRDTSKILRIAASIIIIIFLTSYVGAQFNAGAK 155
+ + F+A+ V +Y E RF ++R AS + I+ ++ A
Sbjct: 124 IPV--------FSALQVGSSYEYLEMRFHS---VVRSIASFMFILDEILFLPFIVYVPAI 172
Query: 156 TLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVG 215
L+ GI++ ++ V++ + Y +GG AV + D + ++M + ++ + ++A
Sbjct: 173 ALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYAN 232
Query: 216 GTEEVLKVLHALDPKLI----NPWAFGAGVVIGFLGIGFG-----SPGQPHIIVRYMSID 266
G VL A +LI NP + V L GF + ++ RYMS+
Sbjct: 233 GL-NVLFDDAAKGGRLIFNNTNPSPYVRHTVWSVLIGGFSYWTSFNAVNQTMVQRYMSLP 291
Query: 267 DPNKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLPG---KNAEMIYPYLSAQYF 323
K R S + T +VGL + D L + + + P Q
Sbjct: 292 SLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQLLPLFVVQSV 351
Query: 324 PPI--LYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVT 381
I + G+ I GIF A LS+ L + +++D+ + K + E+ + + + T
Sbjct: 352 GHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFK--MQPSERASTILVKST 409
Query: 382 VLVVGFLAAILAYVAKD---IIFWFVLFAWGGLGASFGP-TLILSLYWK---GTTKWGVL 434
V+V+GF+A L +V + I+ G +FG TL + + W GT G+
Sbjct: 410 VIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVGGIA 469
Query: 435 AGMIVGTIT 443
+ ++ G I+
Sbjct: 470 SALLAGWIS 478
>emb|CAC16517.1| (AL450223) putative integral membrane transport protein
[Streptomyces coelicolor]
Length = 523
Score = 82.7 bits (201), Expect = 9e-15
Identities = 122/510 (23%), Positives = 214/510 (41%), Gaps = 58/510 (11%)
Query: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73
LV + LI +G R KS +D+FVG M TV+ S V++ S V+ + G
Sbjct: 6 LVVIVVYLIGIAWIGLRKAGRQKSAKDYFVGEGHMPWWTVSFSVVATETSVLTVISVPGG 65
Query: 74 AYK-MGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRI 132
AY G V A+GY+V V + L +R ++ Y RF L+
Sbjct: 66 AYSGQGFGNVELALGYVVGR----VVVATVLIPLYKRGGFVSAYQYLGDRF---GLKLQG 118
Query: 133 AASIIIIIFLTSYVGAQFNAGA---KTLSTALGI--SIFTALMISVLMIIVYMILGGFIA 187
AS+ + G + A A K L G+ S +++ L+ +VY LGG A
Sbjct: 119 LASVTFVFTRLLAEGVRLFASAIPIKLLLDEFGVHASYRAIIIVITLITVVYTYLGGIKA 178
Query: 188 VAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHA-----------LDPKLINPWA 236
V + D I+ V+ + G V+ + A VGG + + L A L L +P+A
Sbjct: 179 VIWTDAIQMVLYLGGAVLAVAVLSAHVGG-DGYARALDAGKFQLFDTDFNLAHILTSPFA 237
Query: 237 FGAGVVIGFLGIGFGSPGQPHIIVRYM----SIDDPNKLRVSTVVGTFWNVVLAWGAIFV 292
++ G + S G +IV+ + ++ + K +++ G F V A ++
Sbjct: 238 LPTAIIGGAI-FAMASHGSDQLIVQRVLATRTLREGQKAMIAS--GVFVTVQFAAFSLVG 294
Query: 293 GL-----AGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQL 347
L GR+ ++L +++ +YP P ++ G+L+ GI A + + S L
Sbjct: 295 ALLWSYNEGRSF----AELGLSSSDNLYPEFILHGLPVVVSGLLVAGILGAAMGSLSSAL 350
Query: 348 LVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYV----AKDIIFWF 403
++++ V D+ + + E+ L ++R LV L A+ A ++
Sbjct: 351 NSMSNSTVADIIHSFFR--STPSEEALLRLARWMTLVWATLMAVFACAFSASTGNVYLTG 408
Query: 404 VLFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMI-VGTITTIVWKLYLKPITG------ 456
+ A GA G L+ L + V+A ++ +G +T IV + + TG
Sbjct: 409 LTIAGYTYGALLGAFLLGRLVKRANEVDSVVAFLVTIGVMTYIVRGVKIDVTTGGTTVSQ 468
Query: 457 ---LYELVP-AFIFSLIATIIVSMITKPPE 482
LVP + +L+ ++S+ + PE
Sbjct: 469 AIAAQWLVPIGVLITLLVGGVLSLFHRAPE 498
>emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Streptomyces
coelicolor A3(2)]
Length = 527
Score = 81.9 bits (199), Expect = 1e-14
Identities = 95/418 (22%), Positives = 184/418 (43%), Gaps = 40/418 (9%)
Query: 25 ILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKMGVTA--V 82
+ +G ++ KR DFF G M +S SG S+ + G +G+AY GVT+
Sbjct: 17 VAIGVWSHKRVDDVSDFFTAGGKMPWWLSGISHHMSGYSAVMFTGYAGIAYTYGVTSFVT 76
Query: 83 WA---AVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR-DTSKILRIAASIII 138
W+ A+G + R+ + R + + +Y + R+ T + L + ++
Sbjct: 77 WSFPIALGVAIGSKL----FAPRINRLRSRLHVASPLEYLKNRYNLPTQQALAWSGMLLK 132
Query: 139 IIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDVIRAVI 198
I+ V A++ A A LS GI++ ++I+ ++ +Y +GG A A ++ + +I
Sbjct: 133 IV----DVAAKWAAIATLLSVFTGITLNQGILITGVITGIYCTIGGLWADALTELGQFII 188
Query: 199 MIIGLVVLPVIAVAKVGGTEEVLKV-----LHALDPKLINPWAFGAGVVIGFLGIGF--G 251
++ V + V V K+G V L L+ P +G ++ FL I
Sbjct: 189 QLLAGVAMFVAVVMKLGDHGGFFGVWDEPALQGHGKPLVGP--YGTVFLLAFLFIKLFEY 246
Query: 252 SPGQPHIIVRYMSIDDPNK----LRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPDVSQLP 307
+ G + RYM+ + + R+S V+ W +VL F + ++ + +
Sbjct: 247 NGGMLNQAQRYMATANAREATRGARLSAVLWLVWPLVL-----FFPMWMSPLLVESQKAD 301
Query: 308 GKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGT 367
G ++ Y ++ Q P L G++I G F+ ++ S +A+ +D+ + K+
Sbjct: 302 GSDS---YALMTEQLLPHGLLGLVIVGFFSHTMAMCSSDANAIAAVFTRDVAPVLSKRAR 358
Query: 368 KIDEKTALTISRV-TVLVVGFLAAILAYV----AKDIIFWFVLFAWGGLGASFGPTLI 420
+++ L +R+ TV+ +G A+ V KDII + + G +G P ++
Sbjct: 359 GWGQRSGLLAARLTTVIFLGLSMAVATQVDSPTFKDIITVVIKWVAGLMGPIAIPMML 416
>emb|CAC11445.1| (AL445063) conserved hypothetical membrane protein [Thermoplasma
acidophilum]
Length = 495
Score = 78.8 bits (191), Expect = 1e-13
Identities = 109/489 (22%), Positives = 205/489 (41%), Gaps = 53/489 (10%)
Query: 22 ILPILVGFYAMKRTKSE----EDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKM 77
+L +L+GF A + ++ +GGR + V + +++ + + Y +
Sbjct: 4 VLFVLIGFLAKNFRRGNLNQLPEWALGGRRLGTFLVWFLVGADLYTAYTFIAVPSSMYAV 63
Query: 78 GVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIAASII 137
G + + AV Y+ + +L S++ +T D+ RF + + IA + I
Sbjct: 64 G-SIYFFAVPYVSLAFAIAMITMPKLWTLSKKRGYVTAGDFVSDRFNSNALAMIIALTGI 122
Query: 138 IIIFLTSYVGAQFNAGAKTLSTAL--------GISIFTALMISVLMIIVYMILGGFIAVA 189
+ Y+ Q G + + T + ++ AL++++L++I + G +
Sbjct: 123 VAEL--PYIALQI-VGMRAILTGMLTPLGGNVDLASNIALVLAILVLIGFTYTSGLRGTS 179
Query: 190 YNDVIR-AVIMIIGLVVLPVIAVAKVGGTEEV--LKVLHA-LDPKLINP-WAFGAGVVIG 244
V++ A+I +VV+ + VA E +K ++A L PK N W
Sbjct: 180 LTAVMKDAIIFTTVIVVIVTVFVAYHSALHEAFTVKPVYADLPPKFYNAYWTL------- 232
Query: 245 FLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIF-VGLAGRAIVPDV 303
FL PH I +S KLR+ST + + + LA+ A+F V + G V
Sbjct: 233 FLMSAAALYLYPHAINGSLSSMSAQKLRLSTALLPIYGIGLAFLALFGVIIYGVPAAEHV 292
Query: 304 SQLP-GKNAEMIYPYLSAQYFPP-----ILYGILIGGIF-AAILSTADSQLLVVASTVVK 356
++ N M+ P L A P GI IGG+ AAI+S SQ ++ V+K
Sbjct: 293 LKITYANNGAMVVPTLIATVTPSWFTGFAFLGIFIGGLVPAAIMSM--SQATLLTRNVIK 350
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFG 416
L G +++EK I++V+++ LA ++ + + G +
Sbjct: 351 YL-------GRELEEKRETFIAKVSMIFFQLLALAFVFIVPETYSISLQLIGGIIILQTL 403
Query: 417 PTLILSLYWKGTTKWGVLAGMIVGTITTIVWKLYLKPITGLYELVP--------AFIFSL 468
P + L +Y K K+ V AG + G + I +++Y + Y ++ FIF
Sbjct: 404 PAVFLGMYVKRLEKYAVAAGWLAGIVAGIYFEVYSNFVYFKYSIIKTTLMPSSLGFIFVG 463
Query: 469 IATIIVSMI 477
+++++I
Sbjct: 464 FTALVINLI 472
>gb|AAF57193.1| (AE003779) CG2191 gene product [Drosophila melanogaster]
Length = 591
Score = 76.9 bits (186), Expect = 5e-13
Identities = 98/434 (22%), Positives = 181/434 (41%), Gaps = 61/434 (14%)
Query: 18 LFTLILPILV------GFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLS 71
+F L+L I GF+A K + E++ +GG+ M I +A+S V+S S+ ++ +
Sbjct: 31 VFALVLSISAAIGVYFGFFA-KGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIP 89
Query: 72 GMAYKMGVTAVWAAVGYI-VAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKIL 130
Y G+ V+ V + V + ++ + + N +Y E RF ++L
Sbjct: 90 AEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNN-----NITNCYEYLEMRFCRKVRVL 144
Query: 131 RIAASII-------IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+ I+ I IFL S AQ T + + ++ S+ + Y + G
Sbjct: 145 QTFIFILTMFFMLPIFIFLPSLAFAQV--------TGFNVHLINTVVCSIC--VFYTMFG 194
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVL---HALD----------PK 230
G AV + DVI+A IM+ +V++ V+ +VGG EVL++ LD
Sbjct: 195 GIKAVVWTDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDINYNFDLTTRST 254
Query: 231 LINPWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAI 290
+ N + + G++G+ + R +S+ R S V+ F +++ +
Sbjct: 255 IWNIFTSATMMWTGYVGL------NQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNC 308
Query: 291 FVGLAGRAIVPDVSQLPG---KNAEMIYPYLSAQYFPPI--LYGILIGGIFAAILSTADS 345
F G+ + D + + + PY + + G+ I +F+A LST +
Sbjct: 309 FTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSA 368
Query: 346 QLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDI-IFWFV 404
+ + V Y + IK + E A I ++ V G + V ++ V
Sbjct: 369 SINSLGGVV----YFDYIKPHIRHTEHRANVIMKLFVFFTGIYCILGGMVIENFNSILQV 424
Query: 405 LFAWGGLGASFGPT 418
+++ GG+ SFG T
Sbjct: 425 IYSIGGM--SFGST 436
>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter), member 2;
solute carrier family 5 (sodium/glucose transporter),
member 2 [Homo sapiens] >gi|400337|sp|P31639|SL52_HUMAN
SODIUM/GLUCOSE COTRANSPORTER 2 (NA(+)/GLUCOSE
COTRANSPORTER 2) (LOW AFFINITY SODIUM-GLUCOSE
COTRANSPORTER) >gi|1082791|pir||A56765 sodium-glucose
cotransporter homolog - human >gi|338053|gb|AAA36608.1|
(M95549) sodium/glucose cotransporter-like protein [Homo
sapiens]
Length = 672
Score = 76.5 bits (185), Expect = 7e-13
Identities = 106/547 (19%), Positives = 214/547 (38%), Gaps = 88/547 (16%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGRSS 64
++ NP ++ +L I VG ++M RT + +F+ GR+M V S +S S
Sbjct: 19 LIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGS 78
Query: 65 WLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+GL+G G+ A G+ +F + +G IT+P Y RF
Sbjct: 79 GHFVGLAGTGAASGL----AVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFG 134
Query: 125 DTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+ +R+ S++ + +++ + + +GA + ALG +I+ +++ + + ++Y + G
Sbjct: 135 --GRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTG 192
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHAL-------DPKLIN-- 233
G A+ Y D ++ +++ G +L A +VGG + K L A DP + N
Sbjct: 193 GLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNIS 252
Query: 234 ----------------------PW---AFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDP 268
PW G +V G+ I+ R ++
Sbjct: 253 SFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWC-----SDQVIVQRCLAGKSL 307
Query: 269 NKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD------------VSQLPGKNAEMIYP 316
++ ++ + + + + G+ R + PD V + + YP
Sbjct: 308 THIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYP 367
Query: 317 YLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALT 376
L + P L G+++ + AA++S+ S ++ D+Y + + ++ L
Sbjct: 368 RLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRL---RPRAGDRELLL 424
Query: 377 ISR-----VTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK- 430
+ R + V+ V +L + A +F ++ L +L+L+ +
Sbjct: 425 VGRLWVVFIVVVSVAWLPVVQAAQGGQ-LFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQ 483
Query: 431 ---WGVLAGMIVGTITTI--------------VWKLYLKPITGLYELVPAFIFSLIATII 473
WG++ G+++G I +L + LY + F S + T+
Sbjct: 484 GAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLT 543
Query: 474 VSMITKP 480
VS+ T P
Sbjct: 544 VSLCTAP 550
>prf||1909123A Na glucose cotransporter [Homo sapiens]
Length = 672
Score = 76.5 bits (185), Expect = 7e-13
Identities = 106/547 (19%), Positives = 214/547 (38%), Gaps = 88/547 (16%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGRSS 64
++ NP ++ +L I VG ++M RT + +F+ GR+M V S +S S
Sbjct: 19 LIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGS 78
Query: 65 WLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+GL+G G+ A G+ +F + +G IT+P Y RF
Sbjct: 79 GHFVGLAGTGAASGL----AVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFG 134
Query: 125 DTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+ +R+ S++ + +++ + + +GA + ALG +I+ +++ + + ++Y + G
Sbjct: 135 --GRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTG 192
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHAL-------DPKLIN-- 233
G A+ Y D ++ +++ G +L A +VGG + K L A DP + N
Sbjct: 193 GLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNIS 252
Query: 234 ----------------------PW---AFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDP 268
PW G +V G+ I+ R ++
Sbjct: 253 SFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWC-----SDQVIVQRCLAGKSL 307
Query: 269 NKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD------------VSQLPGKNAEMIYP 316
++ ++ + + + + G+ R + PD V + + YP
Sbjct: 308 THIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYP 367
Query: 317 YLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALT 376
L + P L G+++ + AA++S+ S ++ D+Y + + ++ L
Sbjct: 368 RLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRL---RPRAGDRELLL 424
Query: 377 ISR-----VTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK- 430
+ R + V+ V +L + A +F ++ L +L+L+ +
Sbjct: 425 VGRLWVVFIVVVSVAWLPVVQAAQGGQ-LFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQ 483
Query: 431 ---WGVLAGMIVGTITTI--------------VWKLYLKPITGLYELVPAFIFSLIATII 473
WG++ G+++G I +L + LY + F S + T+
Sbjct: 484 GAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLT 543
Query: 474 VSMITKP 480
VS+ T P
Sbjct: 544 VSLCTAP 550
>sp|P53792|SL52_RAT SODIUM/GLUCOSE COTRANSPORTER 2 (NA(+)/GLUCOSE COTRANSPORTER 2) (LOW
AFFINITY SODIUM-GLUCOSE COTRANSPORTER)
>gi|1098607|gb|AAC52325.1| (U29881) low affinity
sodium-glucose cotransporter [Rattus norvegicus]
Length = 670
Score = 76.5 bits (185), Expect = 7e-13
Identities = 101/512 (19%), Positives = 207/512 (39%), Gaps = 76/512 (14%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGRSS 64
++ NP ++ +L I VG ++M RT + +F+ GR+M V S +S S
Sbjct: 17 LIDNPADILVIAAYFLLVIGVGLWSMFRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGS 76
Query: 65 WLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+GL+G G+ A G+ +F + +G IT+P Y RF
Sbjct: 77 GHFVGLAGTGAASGL----AVAGFEWNALFVVLLLGWLFVPVYLTAGVITMPQYLRKRFG 132
Query: 125 DTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+ +R+ S++ + +++ + + +GA + ALG +I+ +++ + + ++Y + G
Sbjct: 133 --GRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTG 190
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHAL-------DPKLIN-- 233
G A+ Y D ++ +++ G +L A +VGG + K L A+ DP + N
Sbjct: 191 GLAALMYTDTVQTFVILAGAFILTGYAFHEVGGYSGLFDKYLGAVTSLTVSKDPAVGNIS 250
Query: 234 ----------------------PWAFGAGVVIGFLGI-GFGSPGQPHIIVRYMSIDDPNK 270
PW +++G + G+ I+ R ++ +
Sbjct: 251 STCYQPRPDSYHLLRDPVTGGLPW---PALLLGLTIVSGWHWCSDQVIVQRCLAGKNLTH 307
Query: 271 LRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD---------VSQLPGKN---AEMIYPYL 318
++ ++ + ++ + + G+ R + PD ++ G + + YP L
Sbjct: 308 IKAGCILCGYLKLMPMFLMVMPGMISRILYPDEVACVVPEVCKRVCGTEVGCSNIAYPRL 367
Query: 319 SAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALTIS 378
+ P L G+++ + AA++S+ S ++ D+Y + + ++ L +
Sbjct: 368 VVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRL---RPRAGDRELLLVG 424
Query: 379 RV-TVLVVGFLAAILAYVAK---DIIFWFVLFAWGGLGASFGPTLILSLYWKGTTKWGVL 434
R+ V +V A L V +F ++ L +L+L+ + G
Sbjct: 425 RLWVVFIVAVSVAWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVLALFVPRVNEKGAF 484
Query: 435 AGMIVGTITTIVWKLYLKPITGLYELVPAFIF 466
G+I G + GL L+P F F
Sbjct: 485 WGLIGGL------------LMGLARLIPEFFF 504
>sp|P26430|SL52_RABIT SODIUM/NUCLEOSIDE COTRANSPORTER (NA(+)/NUCLEOSIDE COTRANSPORTER)
>gi|284676|pir||A42251 nucleoside transport protein -
rabbit >gi|165551|gb|AAA31421.1| (M84020) Na+/nucleoside
cotransporter [Oryctolagus cuniculus]
Length = 672
Score = 76.1 bits (184), Expect = 9e-13
Identities = 110/546 (20%), Positives = 214/546 (39%), Gaps = 87/546 (15%)
Query: 7 MLKNPVALVAFLFTLILPILVGFYAMKRTK--SEEDFFVGGRAMDKITVALSAVSSGRSS 64
++ NP + +L I VG ++M RT + +F+ GR+M V S +S S
Sbjct: 19 LIDNPADIAVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGS 78
Query: 65 WLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+GL+G G+ A G+ +F + +G IT+P Y RF
Sbjct: 79 GHFVGLAGTGAANGL----AVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFG 134
Query: 125 DTSKILRIAASII-IIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILG 183
+R+ S++ + +++ + + +GA + ALG +I+ +++ + + +VY + G
Sbjct: 135 GHR--IRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMVYTVTG 192
Query: 184 GFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVL-KVLHAL-------DPKLIN-- 233
G A+ Y D ++ ++I G +L A +VGG + K + A+ DP + N
Sbjct: 193 GLAALMYTDTVQTFVIIAGAFILTGYAFHEVGGYSGLFDKYMGAMTSLTVSEDPAVGNIS 252
Query: 234 ----------------------PW---AFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDP 268
PW G +V G+ I+ R ++ +
Sbjct: 253 SSCYRPRPDSYHLLRDPVTGDLPWPALLLGLTIVSGWYWC-----SDQVIVQRCLAGRNL 307
Query: 269 NKLRVSTVVGTFWNVVLAWGAIFVGLAGRAIVPD---------VSQLPGKN---AEMIYP 316
++ ++ + + + + G+ R + PD ++ G + + YP
Sbjct: 308 THIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVAPEVCKRVCGTEVGCSNIAYP 367
Query: 317 YLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGTKIDEKTALT 376
L + P L G+++ + AA++S+ S ++ D+Y + G E L
Sbjct: 368 RLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTLRPRAG----EGELLL 423
Query: 377 ISRV-TVLVVGFLAAILAYVAK---DIIFWFVLFAWGGLGASFGPTLILSLYWKGTTK-- 430
+ R+ V +V A L V +F ++ L +++L+ +
Sbjct: 424 VGRLWVVFIVAVSVAWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVVALFVPRVNEKG 483
Query: 431 --WGVLAGMIVGTITTI--------------VWKLYLKPITGLYELVPAFIFSLIATIIV 474
WG++ G+++G I +L + LY + F S + IIV
Sbjct: 484 AFWGLIGGLLMGLARLIPEFSFGTGSCVRPSACPAFLCRVHYLYFAIVLFFCSGLLIIIV 543
Query: 475 SMITKP 480
S+ T P
Sbjct: 544 SLCTAP 549
>emb|CAB94614.1| (AL359214) putative permease [Streptomyces coelicolor A3(2)]
Length = 532
Score = 74.5 bits (180), Expect = 3e-12
Identities = 103/521 (19%), Positives = 205/521 (38%), Gaps = 62/521 (11%)
Query: 10 NPVALVAFLFTLILPILVGFYAMKRTKSE-----EDFFVGGRAMDKITVALSAVSSGRSS 64
N VAL F+F +L +GF A + ++E +++ +GGR+ ++
Sbjct: 2 NGVALAVFIFFFVLVTAMGFLAARWRRAENEHSLDEWGLGGRSFGTWVTWFLLGGDLYTA 61
Query: 65 WLVLGLSGMAYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFR 124
+ + + Y G + +A I+ F ++ RL S + +T D+ RF
Sbjct: 62 YTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLP-RLWSVSHKHGYVTTSDFVRGRF- 119
Query: 125 DTSKILRIAASIIIIIFLTSYVGAQFNAGAKTLSTALGIS---------IFTALMISVLM 175
SK L +A ++ I+ Y+ Q G + + +G+ L+I+ +
Sbjct: 120 -GSKGLSLAVAVTGILATMPYIALQL-VGIQAVLDVMGVGGGEDTNWFVKDLPLLIAFGV 177
Query: 176 IIVYMILGGFIAVAYNDVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLH---------A 226
+ Y G A A ++ ++ I + V + K+GG +++
Sbjct: 178 LAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGGFDDIFASASDKFTAAGKGG 237
Query: 227 LDPKLINPWAFGAGVVIGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLA 286
+ P W + LG PH I +S +R +T + ++++L
Sbjct: 238 VVPDAGGQWTYATLA----LGSALALFMYPHSITATLSSRSREVIRRNTTILPLYSLMLG 293
Query: 287 WGAI--FVGLAGRAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTAD 344
A+ F+ +A V N ++ P L FP G+ I L A
Sbjct: 294 LLALLGFMAIAAGVKV--------DNGQLAIPQLFENMFPDWFAGVAFAAIGIGALVPAA 345
Query: 345 SQLLVVASTVVKDLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFV 404
+ A+ +++Y++ IK ++T ++ ++ VG L +L + K + F
Sbjct: 346 IMSIAAANLFTRNIYKDFIKPDATPQQETKVSKLVSLLVKVGALIFVLG-MDKTVAINFQ 404
Query: 405 LFAWGGLGASFGPTLILSLYWKGTTKWGVLAGMIVGTI-TTIVWKLYLKP---------- 453
L + +F P L+ L+ + +W +L G VG + T+ P
Sbjct: 405 LLGGIWILQTF-PALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPTQKHFGGSSD 463
Query: 454 -ITGLYEL----VPAFIFSLIATIIVSMI---TKPPENVEE 486
I G+ E+ + AF+ +++ T++++ + K P+ V+E
Sbjct: 464 EIPGIGEIGYIGLTAFVLNVLVTVVLTFVLRAVKAPDGVDE 504
>gb|AAF55596.1| (AE003723) CG7720 gene product [alt 1] [Drosophila melanogaster]
>gi|7300440|gb|AAF55597.1| (AE003723) CG7720 gene
product [alt 2] [Drosophila melanogaster]
Length = 681
Score = 71.4 bits (172), Expect = 2e-11
Identities = 101/448 (22%), Positives = 189/448 (41%), Gaps = 50/448 (11%)
Query: 20 TLILPILVGFYAMKRTKSEED--FFVGGRAMDKITVALSAVSSGRSSWLVLGLSGMAYKM 77
T++ P+ + K+ +S+ D F GG ++ + ++++ + G S VLG Y
Sbjct: 22 TVLGPLWKRIFGKKKERSKADYVFATGGVSIVAVMISIARGTLGVRS--VLGYPSELYYR 79
Query: 78 GVTAVWAAV-----GY-IVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILR 131
G +A+W + Y IV MF VY + + +V Y + RF+ S+ +R
Sbjct: 80 G-SAMWEIIYGMMSAYPIVCFMFVPVYFNLGIT---------SVYQYIDLRFK--SRTVR 127
Query: 132 IAASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYN 191
AS I+ +G + LST +GI + ++ ++ I + I+GG A
Sbjct: 128 CLASATYIVRQICNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINA 187
Query: 192 DVIRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVI------GF 245
DVI+ V +++ V + + GG ++V ++ D +N W F + + +
Sbjct: 188 DVIQTVTILVVTVAVCIQGTISTGGVKKVYQLNR--DNGRLNFWNFTGDMTVRVDTTSAW 245
Query: 246 LGIGFGSPG----QPHIIVRYMSIDDPNKLR---VSTVVGTFWNVVLAWGAIFVGLAGRA 298
LG F S Q + + RY+S+ ++R ++ V F+ ++W + V +
Sbjct: 246 LGQLFMSLSQIGCQQNFMQRYVSLKSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYI 305
Query: 299 IVPDVSQLPGKNAEMIYPYLSAQY--FPPILYGILIGGIFAAILSTADSQLLVVASTVVK 356
++ K + I P+ F P GI + +F L S L +A+ + +
Sbjct: 306 NCDPYAEGYIKKPDEILPFFVEDQLGFLPGFVGIFMATLFNGALCMMVSNLNSLATVIWE 365
Query: 357 DLYQEVIKKGTKIDEKTALTISRVTVLV------VGFLAAILAYVAKDIIFWFVLFAWGG 410
D ++ K D++ + +TV+ V F +LA V + + F +
Sbjct: 366 DFISQLPKFKGLSDKQQLRILKSITVVCGLIIMGVAFGVGLLAGVIESSLLVFSATSGPL 425
Query: 411 LGASFGPTLILSLYWKGTTKWGVLAGMI 438
LG ++ WKGT+ AGM+
Sbjct: 426 LGCFILAMMVPIANWKGTS-----AGMV 448
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.327 0.143 0.421
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 168319373
Number of Sequences: 2977
Number of extensions: 6928813
Number of successful extensions: 27778
Number of sequences better than 1.0e-10: 143
Number of HSP's better than 0.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 27201
Number of HSP's gapped (non-prelim): 203
length of query: 492
length of database: 189,106,746
effective HSP length: 54
effective length of query: 438
effective length of database: 156,788,448
effective search space: 68673340224
effective search space used: 68673340224
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 167 (69.5 bits)