BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2358 (thiL) DE:thiamine monophosphate kinase (thiL)
(310 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75153 thiamin monophosphate kinase (thil) PAB2358 - Pyroco... 613 e-175
sp|O59497|THIL_PYRHO PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THI... 457 e-128
sp|O27447|THIL_METTH PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THI... 194 1e-48
sp|Q60337|THIL_METJA PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THI... 166 2e-40
pir||G70481 thiamin monophosphate kinase - Aquifex aeolicus >gi|... 147 2e-34
gi|11498340 thiamine monophosphate kinase (thiL) [Archaeoglobus ... 134 1e-30
sp|P57532|THIL_BUCAI THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHO... 129 3e-29
sp|O05514|THIL_BACSU THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHO... 125 5e-28
dbj|BAA19714.1| (D88802) H. influenzae hypothetical protein; E64... 125 5e-28
pir||F83140 thiamine monophosphate kinase PA4051 [imported] - Ps... 125 6e-28
pir||T35646 probable thiamin monphosphate kinase - Streptomyces ... 119 5e-26
gb|AAG20179.1| (AE005095) thiamine monophosphate kinase; ThiL [H... 118 6e-26
pir||E64115 thiamin-phosphate kinase (EC 2.7.4.16) - Haemophilus... 116 4e-25
sp|Q57190|THIL_HAEIN THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHO... 116 4e-25
pir||A82098 thiamin-monophosphate kinase VC2266 [imported] - Vib... 115 9e-25
sp|P77785|THIL_ECOLI THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHO... 113 2e-24
dbj|BAA21778.1| (D17333) thiamine-monophosphate kinase [Escheric... 113 2e-24
sp|P55881|THIL_SALTY THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHO... 111 1e-23
pir||F70672 probable thiL - Mycobacterium tuberculosis (strain H... 108 1e-22
pir||F81205 thiamin-monophosphate kinase NMB0385 [imported] - Ne... 107 2e-22
pir||H81781 thiamin-phosphate kinase (EC 2.7.4.16) NMA2103 [impo... 106 3e-22
dbj|BAB04263.1| (AP001508) thiamin-monophosphate kinase [Bacillu... 106 5e-22
sp|Q58089|Y676_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION P... 101 9e-21
gb|AAF18279.1| (AF088897) thiamin-monophosphate kinase [Zymomona... 94 2e-18
emb|CAC11666.1| (AL445064) thiamine monophosphate kinase related... 92 1e-17
pir||S74650 hypothetical protein slr1787 - Synechocystis sp. (st... 88 1e-16
pir||E82741 thiamin monophosphate kinase XF0956 [imported] - Xyl... 87 3e-16
pir||A81292 probable thiamin-phosphate kinase (EC 2.7.4.16) Cj14... 84 2e-15
sp|Q54757|THIL_SYNP7 THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHO... 83 5e-15
pir||D71121 probable hydrogenase expression/formation protein - ... 81 2e-14
pir||E75040 hydrogenase expression/formation protein (hype) PAB0... 80 3e-14
pir||B69125 hydrogenase expression/formation protein HypE - Meth... 78 1e-13
pir||A70388 hydrogenase expression/formation protein - Aquifex a... 74 2e-12
emb|CAC02001.1| (AL390114) probable thiamine-monophosphate kinas... 72 1e-11
>pir||H75153 thiamin monophosphate kinase (thil) PAB2358 - Pyrococcus abyssi
(strain Orsay) >gi|5457821|emb|CAB49311.1| (AJ248284)
thiamine monophosphate kinase (thiL) [Pyrococcus abyssi]
Length = 310
Score = 613 bits (1564), Expect = e-175
Identities = 310/310 (100%), Positives = 310/310 (100%)
Query: 1 MVVSMREGEIISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAG 60
MVVSMREGEIISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAG
Sbjct: 1 MVVSMREGEIISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAG 60
Query: 61 RKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTN 120
RKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTN
Sbjct: 61 RKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTN 120
Query: 121 EADDIIIDGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKA 180
EADDIIIDGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKA
Sbjct: 121 EADDIIIDGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKA 180
Query: 181 RNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS 240
RNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS
Sbjct: 181 RNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS 240
Query: 241 DPVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWE 300
DPVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWE
Sbjct: 241 DPVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWE 300
Query: 301 HLAGGIDVEL 310
HLAGGIDVEL
Sbjct: 301 HLAGGIDVEL 310
>sp|O59497|THIL_PYRHO PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|7446700|pir||B71195 hypothetical protein PH1833 -
Pyrococcus horikoshii >gi|3258270|dbj|BAA30953.1|
(AP000007) 309aa long hypothetical protein [Pyrococcus
horikoshii]
Length = 309
Score = 457 bits (1164), Expect = e-128
Identities = 217/309 (70%), Positives = 266/309 (85%)
Query: 2 VVSMREGEIISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGR 61
+ MRE EII +F++ F+ H+LGDDAGF++ N+SWLLVTSDMLVW+TDVPDFMTPE+AG+
Sbjct: 1 MTKMRESEIIRMFIEEFDNHALGDDAGFVRFNDSWLLVTSDMLVWRTDVPDFMTPEEAGK 60
Query: 62 KVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNE 121
KVVTMNVSDIAAMGG P+AFFFSL VP + E LRGIA+GIN+G+K Y +KIVSGDTNE
Sbjct: 61 KVVTMNVSDIAAMGGLPLAFFFSLGVPENTDEKTLRGIAKGINKGAKEYGVKIVSGDTNE 120
Query: 122 ADDIIIDGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKAR 181
A +IIIDGG++G G RLLLRSNAKPGDLVCVTG+LGRPLTALLLW++GE+IP +I EKA+
Sbjct: 121 AREIIIDGGAIGRGSRLLLRSNAKPGDLVCVTGELGRPLTALLLWLKGEEIPPKILEKAK 180
Query: 182 NPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVSD 241
NP+AR EG++LS+ ANSAIDISDGLSKELWEIA +SNVRI+I+E+++P+++ V+EIV D
Sbjct: 181 NPKAREREGIELSNYANSAIDISDGLSKELWEIARSSNVRIVIDEDKIPVNEEVREIVKD 240
Query: 242 PVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWEH 301
P+K+ALASGEEFEL+FTIP+E + + DF IIGRVE G GVYIKR K+E L +LGWEH
Sbjct: 241 PIKIALASGEEFELVFTIPKENLGNISFDFTIIGRVEEGEGVYIKREDKMERLPILGWEH 300
Query: 302 LAGGIDVEL 310
L GG V L
Sbjct: 301 LKGGDYVNL 309
>sp|O27447|THIL_METTH PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|7482853|pir||G69052 thiamin monphosphate kinase -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622507|gb|AAB85873.1| (AE000902) thiamine
monphosphate kinase [Methanobacterium
thermoautotrophicum]
Length = 327
Score = 194 bits (487), Expect = 1e-48
Identities = 122/296 (41%), Positives = 176/296 (59%), Gaps = 14/296 (4%)
Query: 23 LGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFF 82
LGDDA I +L++TSD+L+ PD P D G K VT+N+SD+AAMG RP F
Sbjct: 33 LGDDAALIDAGEEFLVLTSDLLLETRHFPDPERPRDMGWKTVTVNMSDLAAMGSRPEGFI 92
Query: 83 FSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDGGSLGIGKR--LLL 140
S+A+P D+ + + G+ E Y+ ++ GDTNEAD+II+ G ++G ++ +L+
Sbjct: 93 LSVALP-DLELEFFDSLMDGVIEACCHYQAPLIGGDTNEADEIILSGTAIGRAEKDMVLM 151
Query: 141 RSNAKPGDLVCVTGDL--GRPLTALLLWMRGEKIPREIEEKARNPRARVEEGVKL--SSL 196
+S A+PGDLV VTG L G T L+L R E++ P AR+EEG+ L S L
Sbjct: 152 KSGARPGDLVAVTGPLGVGAAGTELILSGRDTGGFENAVERSLRPVARIEEGLILAESGL 211
Query: 197 ANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS----DPVKVALASGEE 252
+SA DI+DGL EL E+ +AS + I E+RLP+ V EI S DP+++AL GE+
Sbjct: 212 VSSATDITDGLVSELGELMDASGTGMRIYEDRLPLGREVPEIASILGRDPLELALYYGED 271
Query: 253 FELLFTIPREKVEELD--IDFKIIGRVEGGNGV-YIKRGRKIEELEVLGWEHLAGG 305
FEL+FT P +EEL ++ +IG V G G+ + + +L V G+EHL+ G
Sbjct: 272 FELVFTAPPTGMEELSDMMELHVIGEVTVGGGIEMVDKDGVTYKLHVRGYEHLSPG 327
>sp|Q60337|THIL_METJA PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|2127988|pir||D64303 hypothetical protein HI1305
homolog - Methanococcus jannaschii
>gi|1590830|gb|AAB98008.1| (U67461) thiamine
monphosphate kinase (thiL) [Methanococcus jannaschii]
Length = 319
Score = 166 bits (417), Expect = 2e-40
Identities = 112/323 (34%), Positives = 179/323 (54%), Gaps = 35/323 (10%)
Query: 5 MREGEIISLFMKHFERH---SLGDDAGFIKLN-NSWLLVTSDMLVWKTDVPDFMTPEDAG 60
M+ EII +K + + DD IK++ N +L+ T+DM+V K +P ++P + G
Sbjct: 4 MKVIEIIKKTLKFSNENIVKGIDDDCAIIKIDENFYLVATTDMMVKKAHIPSILSPYEIG 63
Query: 61 RKVVTMNVSDIAAMGGRPMAFFFSLAV-PGDVSEDILRGIARGINEGSKVYKLKIVSGDT 119
+++T NVSDIA+MG +P+AF S+++ + +E ++ + G+++ SK+Y +V GDT
Sbjct: 64 GRILTANVSDIASMGAKPLAFLVSISLSKEEANEKFIKELYSGLDDFSKLYDCPVVGGDT 123
Query: 120 NEADDIIIDGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLW--MRGEKIP-REI 176
N D++I+ G + GI + R K GD +CVT DLGR AL L+ ++ KI +E
Sbjct: 124 NRGDELILSGTAFGITDNPIYR-RGKVGDDICVTNDLGRVYCALTLYYMLKENKISYKEF 182
Query: 177 E----------EKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIAN----ASNVRI 222
E EK R P AR++EG+ ++ L N DISDGL KE+ N + +
Sbjct: 183 ERLCQKYPKIIEKLRKPIARIKEGLLMNKLINGCCDISDGLGKEITYFKNFEIYSDRIFK 242
Query: 223 IIEEERLPISDSVKEIVSDPVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNG 282
+I E+ + D+ +P+KVAL SGEEFELLFT + K+ ++G +
Sbjct: 243 LIPEDVIEFCDAFN---LNPIKVALNSGEEFELLFTTSKFN--------KVKDSLKGYSK 291
Query: 283 VYIKRGRKIEELEVLGWEHLAGG 305
+Y K G+ IE+ + + E GG
Sbjct: 292 IY-KIGKIIEDGQFIDGEEFYGG 313
>pir||G70481 thiamin monophosphate kinase - Aquifex aeolicus
>gi|2984327|gb|AAC07848.1| (AE000774) thiamine
monophosphate kinase [Aquifex aeolicus]
Length = 306
Score = 147 bits (367), Expect = 2e-34
Identities = 100/300 (33%), Positives = 161/300 (53%), Gaps = 13/300 (4%)
Query: 10 IISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVS 69
+I L K E +GDD ++ + LL+T+D+L PE G K +++NVS
Sbjct: 11 LIDLIKKTLESKVIGDDTAPVEYCSKKLLLTTDVLNEGVHFLRSYIPEAVGWKAISVNVS 70
Query: 70 DIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDG 129
D+ A GG P SL +P D+ + G+ + YK ++V G+ ++++ I I
Sbjct: 71 DVIANGGLPKWALISLNLPEDLEVSYVERFYIGVKRACEFYKCEVVGGNISKSEKIGISV 130
Query: 130 GSLGIGKRLLLRSNAKPGDLVCVTGDLG--RPLTALLLWMRGEKIPREIE--EKARNPRA 185
+G +R + R A+ GD V V+G LG R LLL + E P E+ ++ P A
Sbjct: 131 FLVGETERFVGRDGARLGDSVFVSGTLGDSRAGLELLLMEKEEYEPFELALIQRHLRPTA 190
Query: 186 RVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVK----EIVSD 241
R++ + AN+++DISDGL + +A S V+I I E+LP+S+ +K + +
Sbjct: 191 RIDYVKHIQKYANASMDISDGLVADANHLAQRSGVKIEILSEKLPLSNELKMYCEKYGKN 250
Query: 242 PVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWEH 301
P++ AL GE+++LLFT P+E+ +D IGRVE G GV++ G+K+E GW+H
Sbjct: 251 PIEYALFGGEDYQLLFTHPKERWNPF-LDMTEIGRVEEGEGVFVD-GKKVEP---KGWKH 305
>gi|11498340 thiamine monophosphate kinase (thiL) [Archaeoglobus fulgidus]
>gi|6226221|sp|O29525|THIL_ARCFU PROBABLE
THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE
KINASE) >gi|7483977|pir||E69341 thiamin monophosphate
kinase (thiL) homolog - Archaeoglobus fulgidus
>gi|2649878|gb|AAB90505.1| (AE001054) thiamine
monophosphate kinase (thiL) [Archaeoglobus fulgidus]
Length = 296
Score = 134 bits (335), Expect = 1e-30
Identities = 95/307 (30%), Positives = 163/307 (52%), Gaps = 25/307 (8%)
Query: 4 SMREGEIISLFMKHFERHSL-----GDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPED 58
+M+E E+I L + F + DA ++K+ N +++T D + K+D P +M PE+
Sbjct: 5 NMKEFELIKLVERLFGDEDVITPAGKHDAAYVKIGNRLIVLTCDTVNEKSDFPPYMLPEE 64
Query: 59 AGRKVVTMNVSDIAAMGGRPMAFFFSLAVPG-DVSEDILRGIARGINEGSKVYKLKIVSG 117
G + + +SD+AA G RP+ F S+++ + EDIL GI R + + +K+V G
Sbjct: 65 MGWMAIAVTLSDVAACGARPLYFLSSISLKSIEFFEDILLGIKRCADR----FGVKVVGG 120
Query: 118 DTNEADDIIIDGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRG---EKIPR 174
D + ++ I G ++G +R + R AK G+ V +T G+ L + RG E++P
Sbjct: 121 DIDFSEITTIAGFAIGEARRHITRRGAKVGEGVFITDLPGKAQLCLEMLERGAKREELP- 179
Query: 175 EIEEKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDS 234
EK P R+EEG++++ A++ D+SD L+ L +I+ +SNV+I+++ I S
Sbjct: 180 -YAEKLYTPVPRIEEGMRIARYASAMTDVSDSLAVSLHQISQSSNVKIVLDN----IVLS 234
Query: 235 VKEIVSDPVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEEL 294
+ +++ L G +FEL++T D IGRVE G GV+ + K E+
Sbjct: 235 HLSPAENALELFLYGGGDFELVYTAKSSD------DGIRIGRVERGKGVFAEIDGKTFEV 288
Query: 295 EVLGWEH 301
E G+ H
Sbjct: 289 EFRGYSH 295
>sp|P57532|THIL_BUCAI THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|10039123|dbj|BAB13157.1| (AP001119)
thiamin-monophosphate kinase [Buchnera sp. APS]
Length = 323
Score = 129 bits (322), Expect = 3e-29
Identities = 95/279 (34%), Positives = 147/279 (52%), Gaps = 18/279 (6%)
Query: 7 EGEIISLFMKHFERHS------LGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDA 59
E EIIS + K ++ +GDD+ IK+ N+ L +++D LV T ++PED
Sbjct: 5 EFEIISKYFKRNQKKDVNEIKGIGDDSALIKIPKNNILAISTDTLVEGTHFLKNISPEDL 64
Query: 60 GRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDT 119
G K V +N+SD+AAMG P S+ +P + + L+ + + Y ++++ GDT
Sbjct: 65 GYKTVAVNLSDLAAMGAEPKWTTLSITMP-ESNNIWLKKFSSSFFKILNKYNVRLIGGDT 123
Query: 120 NEADDIIIDGGSLGIGKR--LLLRSNAKPGDLVCVTGDLGRPLTALLL-----WMRGEKI 172
N + I G+ K+ LLRSNA GDL+ VTG LG L L +++ I
Sbjct: 124 NRGS-LSITLSMYGLLKKQIALLRSNANIGDLIYVTGTLGESAAGLFLLKKNIFIKNVNI 182
Query: 173 PREIEEKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPIS 232
+ +K NP RV EG+ L +AN+AID+SDGL +L I N S I ++PIS
Sbjct: 183 RNYLIKKHLNPIPRVSEGMALRKIANAAIDLSDGLIADLDHILNDSQCGANINLNKIPIS 242
Query: 233 DSVKEIVSDP--VKVALASGEEFELLFTIPREKVEELDI 269
+ + + AL GE++EL FTI ++ +++L I
Sbjct: 243 KVLIDNFQSQNYLNWALNVGEDYELCFTISKKNIDKLKI 281
>sp|O05514|THIL_BACSU THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|7475872|pir||B69786 thiamin-monophosphate kinase
homolog ydiA - Bacillus subtilis
>gi|2632903|emb|CAB12409.1| (Z99107) alternate gene
name: ydxA~similar to thiamin-monophosphate kinase
[Bacillus subtilis]
Length = 325
Score = 125 bits (312), Expect = 5e-28
Identities = 86/226 (38%), Positives = 127/226 (56%), Gaps = 12/226 (5%)
Query: 53 FMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKL 112
+ +PED G K + +N+SDIAAMGG P + SLAVP +E ++ + G+NE +K+Y +
Sbjct: 56 YSSPEDIGYKALAVNISDIAAMGGIPKFYLVSLAVPSKWTESEIKAMYEGMNELAKLYHM 115
Query: 113 KIVSGDT-NEADDIIIDGGSLG-IGK-RLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRG 169
++ GDT + AD +++ +G I K + LRS AKP D+V VTG++G L L +
Sbjct: 116 DLIGGDTVSTADKLVVTVTVIGEIEKGQACLRSLAKPNDIVFVTGEIGSSAAGLSLLLE- 174
Query: 170 EKIPREIE-------EKARNPRARVEEGVKLSSLANSAI-DISDGLSKELWEIANASNVR 221
E P+ + + P RV G S +A+ D+SDGL+ EL EIA AS V
Sbjct: 175 ETNPQNSSVETDYFIHRHKRPEPRVSVGRLCSIFKRAALNDVSDGLASELNEIAEASCVS 234
Query: 222 IIIEEERLPISDSVKEIVSDPVKVALASGEEFELLFTIPREKVEEL 267
I I E LPI + ++ + + AL GE+FEL T+ E+ E L
Sbjct: 235 IEIVESMLPIHSDLPKLHPNWKEWALFGGEDFELTGTVSNEEWEVL 280
>dbj|BAA19714.1| (D88802) H. influenzae hypothetical protein; E64115 (424) [Bacillus
subtilis]
Length = 351
Score = 125 bits (312), Expect = 5e-28
Identities = 86/226 (38%), Positives = 127/226 (56%), Gaps = 12/226 (5%)
Query: 53 FMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKL 112
+ +PED G K + +N+SDIAAMGG P + SLAVP +E ++ + G+NE +K+Y +
Sbjct: 82 YSSPEDIGYKALAVNISDIAAMGGIPKFYLVSLAVPSKWTESEIKAMYEGMNELAKLYHM 141
Query: 113 KIVSGDT-NEADDIIIDGGSLG-IGK-RLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRG 169
++ GDT + AD +++ +G I K + LRS AKP D+V VTG++G L L +
Sbjct: 142 DLIGGDTVSTADKLVVTVTVIGEIEKGQACLRSLAKPNDIVFVTGEIGSSAAGLSLLLE- 200
Query: 170 EKIPREIE-------EKARNPRARVEEGVKLSSLANSAI-DISDGLSKELWEIANASNVR 221
E P+ + + P RV G S +A+ D+SDGL+ EL EIA AS V
Sbjct: 201 ETNPQNSSVETDYFIHRHKRPEPRVSVGRLCSIFKRAALNDVSDGLASELNEIAEASCVS 260
Query: 222 IIIEEERLPISDSVKEIVSDPVKVALASGEEFELLFTIPREKVEEL 267
I I E LPI + ++ + + AL GE+FEL T+ E+ E L
Sbjct: 261 IEIVESMLPIHSDLPKLHPNWKEWALFGGEDFELTGTVSNEEWEVL 306
>pir||F83140 thiamine monophosphate kinase PA4051 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950247|gb|AAG07438.1|AE004821_11 (AE004821)
thiamine monophosphate kinase [Pseudomonas aeruginosa]
Length = 322
Score = 125 bits (311), Expect = 6e-28
Identities = 90/275 (32%), Positives = 148/275 (53%), Gaps = 14/275 (5%)
Query: 23 LGDDAGFIKLN-NSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAF 81
+GDD + L V++D LV P P ++ + ++ SD+AAMG P+AF
Sbjct: 27 IGDDCALLAPPAGEQLAVSTDTLVEGVHFPAGCDPFLLAQRALAVSASDLAAMGAAPLAF 86
Query: 82 FFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEA--DDIIIDGGSLGIGKRLL 139
+L +P + L+G ARG++ ++ L +V GDT + G + G+ L
Sbjct: 87 TLALTLP-QADAEWLQGFARGLDAMARQCGLALVGGDTTRGPLSMTLTVFGRVPAGQALT 145
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEK--AR--NPRARVEEGVKLSS 195
R+ A+PGDL+CV G LG AL L + P E+ E AR P + G+ L
Sbjct: 146 -RAGARPGDLLCVGGPLGEAGAALELVLERRSAPAEVAEPLLARYWTPAPQFGLGLALRG 204
Query: 196 LANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS--DPVKVALASGEEF 253
A++A+DISDGL + IA AS V +++E +RL S ++ +++ + ++ LA+G+++
Sbjct: 205 KASAALDISDGLLADCGHIARASGVALLVECQRLQASAALSGLLAGEEALRQQLAAGDDY 264
Query: 254 ELLFTIPREKVEELDIDF---KIIGRVEGGNGVYI 285
L+FT+P E + E+ + +IGRVE G GV++
Sbjct: 265 VLVFTLPPEYLGEIRAAWPAMAVIGRVEAGQGVHL 299
>pir||T35646 probable thiamin monphosphate kinase - Streptomyces coelicolor
>gi|4007721|emb|CAA22405.1| (AL034447) putative thiamine
monphosphate kinase [Streptomyces coelicolor A3(2)]
Length = 322
Score = 119 bits (295), Expect = 5e-26
Identities = 87/292 (29%), Positives = 136/292 (45%), Gaps = 10/292 (3%)
Query: 24 GDDAGFIKLNNSWLLVTSDMLVWKTDVP-DFMTPEDAGRKVVTMNVSDIAAMGGRPMAFF 82
GDDA + + ++ ++D+LV D+ T D GRK N++DIAAMG P A
Sbjct: 32 GDDAAVVAAPDRRVVASTDILVEGRHFRRDWSTAYDVGRKAAAQNLADIAAMGAVPTALL 91
Query: 83 FSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDGGSLG--IGKRLLL 140
L VP ++ + G+ + +V +V GD D I + +LG + +
Sbjct: 92 LGLVVPAELPVTWPTELMDGLRDECQVAGASVVGGDVVRGDTITVSITALGDLRNQEPVT 151
Query: 141 RSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKARNPRARVEEGVKLSSLANSA 200
R+ A+PGDLV VTG LG + RG + PR E R P G + L +A
Sbjct: 152 RAGAQPGDLVAVTGWLGWSAAGFAVLSRGFRSPRAFVEAHRRPEPPYHAGPAAAGLGATA 211
Query: 201 I-DISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS----DPVKVALASGEEFEL 255
+ D+SDGL +L IA AS VRI + ++ I + +I DP++ L GE+ +
Sbjct: 212 MCDVSDGLIADLGHIAEASKVRIDVRSGQIDIPSQMNDIGQAVGVDPMQWVLTGGEDHAI 271
Query: 256 LFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWEHLAGGID 307
+ T P + +L +K+IG V + + GW+H G ++
Sbjct: 272 VATFPPD--VKLPARWKVIGEVLNPSALPQVTVDGAPWTSKGGWDHFGGDVE 321
>gb|AAG20179.1| (AE005095) thiamine monophosphate kinase; ThiL [Halobacterium sp.
NRC-1]
Length = 288
Score = 118 bits (294), Expect = 6e-26
Identities = 87/286 (30%), Positives = 140/286 (48%), Gaps = 23/286 (8%)
Query: 24 GDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFF 83
GDDA + +T DML TD P T AG + V ++SD+AA G A
Sbjct: 18 GDDAAVV----GDTALTIDMLHDATDFPSGTTRYTAGWRSVGASLSDVAATGATATAAVA 73
Query: 84 SLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDGGSLGIGKRLLLRSN 143
+ PG +D L G + + V GD + + + ++G + RS
Sbjct: 74 AYGAPG-FDDDELAAFVTGARDVCTAVGAEYVGGDLDGHSEFTVATAAIGDADHRVTRSG 132
Query: 144 AKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKARNP---RARVEEGVKLSSLANSA 200
A+PGD V VTG LGR A+ L+ G+ E+A + RV G L + A +
Sbjct: 133 ARPGDSVVVTGSLGRSAAAMALFDAGDT------ERANDLFQFMPRVAAGRVLGAHATAM 186
Query: 201 IDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVSDPVKVALASGEEFELLFTIP 260
+D SDGL++ L ++A AS+ + ++ RLP++D++ E+ +DPV+ A++ G +FEL+ +P
Sbjct: 187 MDASDGLARSLHQLAAASDCGMAVDSGRLPVADALAEVTADPVERAVSFGGDFELVAAVP 246
Query: 261 REKVE----ELDIDFKIIGRV-EGGNGVYIKRGRKIEELEVLGWEH 301
E+VE + ++GRV +GV + ++ GW H
Sbjct: 247 PERVEAARAAVPGSLSVVGRVTAAADGVRLDGDALADD----GWTH 288
>pir||E64115 thiamin-phosphate kinase (EC 2.7.4.16) - Haemophilus influenzae
(strain Rd KW20) >gi|1574764|gb|AAC22952.1| (U32810)
thiamin-monophosphate kinase (thiL) [Haemophilus
influenzae Rd]
Length = 345
Score = 116 bits (287), Expect = 4e-25
Identities = 80/259 (30%), Positives = 131/259 (49%), Gaps = 9/259 (3%)
Query: 22 SLGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMA 80
S+GDD + + N L +T+D +V T ++PED K V N+SD+AAMG +P
Sbjct: 43 SIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMGAQPKW 102
Query: 81 FFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEAD-DIIIDGGSLGIGKRLL 139
+L +P +V E+ + ++ + K Y + ++ GDT + + I I + +
Sbjct: 103 VSLALTLP-NVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGI 161
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPRE----IEEKARNPRARVEEGVKLSS 195
R A+ GDL+ V+ LG L + G+ ++++ P R+E G L
Sbjct: 162 CRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIG 221
Query: 196 LANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSV--KEIVSDPVKVALASGEEF 253
+A+ AID+SDGL +L I S +E LP+S S+ K + + AL+ GE++
Sbjct: 222 IAHVAIDLSDGLISDLGHILERSQCSAEVELTALPLSSSILNKYDRTQAEQFALSGGEDY 281
Query: 254 ELLFTIPREKVEELDIDFK 272
EL FTIP E +EL++ K
Sbjct: 282 ELCFTIPPEYKDELELRLK 300
>sp|Q57190|THIL_HAEIN THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
Length = 328
Score = 116 bits (287), Expect = 4e-25
Identities = 80/259 (30%), Positives = 131/259 (49%), Gaps = 9/259 (3%)
Query: 22 SLGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMA 80
S+GDD + + N L +T+D +V T ++PED K V N+SD+AAMG +P
Sbjct: 26 SIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMGAQPKW 85
Query: 81 FFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEAD-DIIIDGGSLGIGKRLL 139
+L +P +V E+ + ++ + K Y + ++ GDT + + I I + +
Sbjct: 86 VSLALTLP-NVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGI 144
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPRE----IEEKARNPRARVEEGVKLSS 195
R A+ GDL+ V+ LG L + G+ ++++ P R+E G L
Sbjct: 145 CRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIG 204
Query: 196 LANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSV--KEIVSDPVKVALASGEEF 253
+A+ AID+SDGL +L I S +E LP+S S+ K + + AL+ GE++
Sbjct: 205 IAHVAIDLSDGLISDLGHILERSQCSAEVELTALPLSSSILNKYDRTQAEQFALSGGEDY 264
Query: 254 ELLFTIPREKVEELDIDFK 272
EL FTIP E +EL++ K
Sbjct: 265 ELCFTIPPEYKDELELRLK 283
>pir||A82098 thiamin-monophosphate kinase VC2266 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9656828|gb|AAF95410.1|
(AE004298) thiamin-monophosphate kinase [Vibrio
cholerae]
Length = 334
Score = 115 bits (284), Expect = 9e-25
Identities = 86/256 (33%), Positives = 128/256 (49%), Gaps = 10/256 (3%)
Query: 22 SLGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMA 80
+LGDD +K+ NS + +++D LV T P K + N+SD+AAMG P
Sbjct: 35 ALGDDCAIVKVPENSRVAISTDTLVAGTHFLAQANPAWVAHKALASNISDLAAMGATPAW 94
Query: 81 FFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEAD-DIIIDGGSLGIGKRLL 139
+L +P ++ + L E +K Y ++++ GDT + I + ++ +
Sbjct: 95 VSLALTLP-EIDDAWLTPFCDAFFELAKYYNVQLIGGDTTKGPLSITLTVQGFLPKEQAM 153
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRGEK----IPREIEEKARNPRARVEEGVKLSS 195
LRS AK GD + VTGDLG L + + EK +E++ R+ G L
Sbjct: 154 LRSGAKVGDWLYVTGDLGDSQAGLDVILDPEKRHLPFADILEQRHYLSTPRIVAGQALVH 213
Query: 196 LANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEI---VSDPVKVALASGEE 252
LA+SAIDISDGL +L I SNV I+ LP+S + + V+ + AL SGEE
Sbjct: 214 LASSAIDISDGLIADLQHILRRSNVGASIDVSLLPLSKELLQFVDSVTSAQQYALTSGEE 273
Query: 253 FELLFTIPREKVEELD 268
+EL FTIP E L+
Sbjct: 274 YELCFTIPEENRGSLE 289
>sp|P77785|THIL_ECOLI THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|7466933|pir||A64771 thiamin-phosphate kinase (EC
2.7.4.16) - Escherichia coli >gi|1773101|gb|AAB40173.1|
(U82664) similar to H. influenzae HI1305 [Escherichia
coli] >gi|1786619|gb|AAC73520.1| (AE000148)
thiamin-monophosphate kinase [Escherichia coli K12]
Length = 325
Score = 113 bits (281), Expect = 2e-24
Identities = 96/319 (30%), Positives = 149/319 (46%), Gaps = 29/319 (9%)
Query: 12 SLFMKHFERH---------SLGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDAGR 61
SL ++F+R +GDD + + L +++D LV + P D
Sbjct: 7 SLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAISTDTLVAGNHFLPDIDPADLAY 66
Query: 62 KVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNE 121
K + +N+SD+AAMG P +L +P DV E L + + + Y ++++ GDT
Sbjct: 67 KALAVNLSDLAAMGADPAWLTLALTLP-DVDEAWLESFSDSLFDLLNYYDMQLIGGDTTR 125
Query: 122 ADDIIIDG--GSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALL-----LWMRGEKIPR 174
+ G G + +G R L RS AKPGD + VTG G L L + K
Sbjct: 126 GPLSMTLGIHGFVPMG-RALTRSGAKPGDWIYVTGTPGDSAAGLAILQNRLQVADAKDAD 184
Query: 175 EIEEKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDS 234
+ ++ P R+ +G L LANSAID+SDGL +L I AS+ I+ LP SD+
Sbjct: 185 YLIKRHLRPSPRILQGQALRDLANSAIDLSDGLISDLGHIVKASDCGARIDLALLPFSDA 244
Query: 235 VKEIV--SDPVKVALASGEEFELLFTIPREKVEELD-------IDFKIIGRVEGG-NGVY 284
+ V ++ AL+ GE++EL FT+P LD + F IG++ G+
Sbjct: 245 LSRHVEPEQALRWALSGGEDYELCFTVPELNRGALDVALGHLGVPFTCIGQMTADIEGLC 304
Query: 285 IKRGRKIEELEVLGWEHLA 303
R + L+ G++H A
Sbjct: 305 FIRDGEPVTLDWKGYDHFA 323
>dbj|BAA21778.1| (D17333) thiamine-monophosphate kinase [Escherichia coli]
Length = 325
Score = 113 bits (281), Expect = 2e-24
Identities = 96/319 (30%), Positives = 149/319 (46%), Gaps = 29/319 (9%)
Query: 12 SLFMKHFERH---------SLGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDAGR 61
SL ++F+R +GDD + + L +++D LV + P D
Sbjct: 7 SLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAISTDTLVAGNHFLPDIDPADLAY 66
Query: 62 KVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNE 121
K + +N+SD+AAMG P +L +P DV E L + + + Y ++++ GDT
Sbjct: 67 KALAVNLSDLAAMGADPAWLTLALTLP-DVDEAWLESFSDSLFDLLNYYDMQLIGGDTTR 125
Query: 122 ADDIIIDG--GSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALL-----LWMRGEKIPR 174
+ G G + +G R L RS AKPGD + VTG G L L + K
Sbjct: 126 GPLSMTLGIHGFVPMG-RALTRSGAKPGDWIYVTGTPGDSAAGLAILQNRLQVADAKDAD 184
Query: 175 EIEEKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDS 234
+ ++ P R+ +G L LANSAID+SDGL +L I AS+ I+ LP SD+
Sbjct: 185 YLIKRHLRPSPRILQGQALRDLANSAIDLSDGLISDLGHIVKASDCGARIDLALLPFSDA 244
Query: 235 VKEIV--SDPVKVALASGEEFELLFTIPREKVEELD-------IDFKIIGRVEGG-NGVY 284
+ V ++ AL+ GE++EL FT+P LD + F IG++ G+
Sbjct: 245 LSRHVEPEQELRWALSGGEDYELCFTVPELNRGALDVALGHLGVPFTCIGQMTADIEGLC 304
Query: 285 IKRGRKIEELEVLGWEHLA 303
R + L+ G++H A
Sbjct: 305 FIRDGEPVTLDWKGYDHFA 323
>sp|P55881|THIL_SALTY THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|11279233|pir||T47117 thiamin-phosphate kinase (EC
2.7.4.16) [validated] - Salmonella typhimurium
>gi|1698893|gb|AAB37319.1| (U74758) thiamine
monphosphate kinase [Salmonella typhimurium]
Length = 325
Score = 111 bits (275), Expect = 1e-23
Identities = 91/322 (28%), Positives = 152/322 (46%), Gaps = 35/322 (10%)
Query: 12 SLFMKHFER---------HSLGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDAGR 61
SL ++F+R +GDD + + L +++D LV + P D
Sbjct: 7 SLIARYFDRVRSSRLDVETGIGDDCALLNIPEKQTLAISTDTLVAGNHFLPDIDPADLAY 66
Query: 62 KVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNE 121
K + +N+SD+AAMG P +L +P +V E L + + Y ++++ GDT
Sbjct: 67 KALAVNLSDLAAMGADPAWLTLALTLP-EVDEPWLEAFSDSLFALLNYYDMQLIGGDTTR 125
Query: 122 ADDIIIDG--GSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIE-- 177
+ G G + G R L RS AKPGD + VTG G L + ++ E +
Sbjct: 126 GPLSMTLGIHGYIPAG-RALKRSGAKPGDWIYVTGTPGDSAAGLAVLQNRLQVSEETDAH 184
Query: 178 ---EKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDS 234
++ P R+ G L +A++AID+SDGL +L I AS ++ + LP SD+
Sbjct: 185 YLIQRHLRPTPRILHGQALRDIASAAIDLSDGLISDLGHIVKASGCGARVDVDALPKSDA 244
Query: 235 VKEIVSD--PVKVALASGEEFELLFTIPR-------EKVEELDIDFKIIGR----VEGGN 281
+ V D ++ AL+ GE++EL FT+P + +L + F IG+ +EG N
Sbjct: 245 MMRHVDDGQALRWALSGGEDYELCFTVPELNRGALDVAIGQLGVPFTCIGQMSADIEGLN 304
Query: 282 GVYIKRGRKIEELEVLGWEHLA 303
+++ G + + G++H A
Sbjct: 305 --FVRDGMPV-TFDWKGYDHFA 323
>pir||F70672 probable thiL - Mycobacterium tuberculosis (strain H37RV)
>gi|1694854|emb|CAB05435.1| (Z83018) thiL [Mycobacterium
tuberculosis]
Length = 333
Score = 108 bits (266), Expect = 1e-22
Identities = 83/286 (29%), Positives = 131/286 (45%), Gaps = 15/286 (5%)
Query: 24 GDDAGFIKLNNSWLLVTSDMLVWKTDVP-DFMTPEDAGRKVVTMNVSDIAAMGGRPMAFF 82
GDDA + + +V++DMLV + D+ TP+D GRK + N +DI AMG R AF
Sbjct: 42 GDDAALVSAGDGRTVVSTDMLVQDSHFRLDWSTPQDVGRKAIAQNAADIEAMGARATAFV 101
Query: 83 FSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDGGSLG--IGKRLLL 140
P + + G+ E + IV GD ++ ++G G+ +L
Sbjct: 102 VGFGAPAETPAAQASALVDGMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPVL 161
Query: 141 RSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKARNPRARVEEGVKLSSL-ANS 199
RS AK G ++ V G+LGR LW G + E+ + P+ G +++ A +
Sbjct: 162 RSGAKAGSVLAVVGELGRSAAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQA 221
Query: 200 AIDISDGLSKELWEIANASNVRI-----IIEEERLPISDSVKEIVSDPVKVALASGEEFE 254
ID+SDGL +L IA AS VRI + +R ++ + + +DP L+ GE+
Sbjct: 222 MIDVSDGLLADLRHIAEASGVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHA 281
Query: 255 LLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWE 300
L+ V + ++ IGRV G + G E GW+
Sbjct: 282 LVACF----VGPVPAGWRTIGRVLDGPARVLVDGE--EWTGYAGWQ 321
>pir||F81205 thiamin-monophosphate kinase NMB0385 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225606|gb|AAF40825.1| (AE002394)
thiamin-monophosphate kinase [Neisseria meningitidis
MC58]
Length = 318
Score = 107 bits (264), Expect = 2e-22
Identities = 90/297 (30%), Positives = 148/297 (49%), Gaps = 21/297 (7%)
Query: 23 LGDDAGFIKLNNSW-LLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAF 81
+GDDA ++ + L ++DML+ + PED KV+ +N+SD+AAMG P
Sbjct: 23 IGDDAAIVRPREGFDLCFSADMLLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWV 82
Query: 82 FFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDI--IIDGGSLGIGKRLL 139
S A+P ++ E L+ +K + + ++ GDT + D + G L G R L
Sbjct: 83 LLSAALP-ELDEVWLKRFCGSFFGLAKKFGVTLIGGDTTKGDMAFNVTIIGELPKG-RAL 140
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREI----EEKARNPRARVEEGVKLSS 195
R A GD + V+G +G AL ++ +P E+ E+K +P RV G+ L
Sbjct: 141 RRDAAVAGDDIWVSGRIGMAAAALNCRLKRCVLPDEVFAECEQKLLHPEPRVGLGLALLP 200
Query: 196 LANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIV--SDPVKVALASGEEF 253
A +A D+SDGL+++L I AS I + LP +K+I+ + + LA G+++
Sbjct: 201 FARAAQDVSDGLAQDLGHILTASGKGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDY 260
Query: 254 ELLFTIPR-------EKVEELDIDFKIIGRVEGGNGVYI--KRGRKIEELEVLGWEH 301
EL+FT P + E + IG++ GG + + GR++ EL LG++H
Sbjct: 261 ELVFTAPESCRSRVFDAAERCGVPVTRIGKINGGCRLKVLDADGREL-ELHSLGFDH 316
>pir||H81781 thiamin-phosphate kinase (EC 2.7.4.16) NMA2103 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380728|emb|CAB85319.1| (AL162758)
thiamine-monophosphate kinase [Neisseria meningitidis
Z2491]
Length = 318
Score = 106 bits (263), Expect = 3e-22
Identities = 90/297 (30%), Positives = 147/297 (49%), Gaps = 21/297 (7%)
Query: 23 LGDDAGFIKLNNSW-LLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAF 81
+GDDA ++ + L ++DML+ + PED KV+ +N+SD+AAMG P
Sbjct: 23 IGDDAAIVRPREGFDLCFSADMLLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWV 82
Query: 82 FFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDI--IIDGGSLGIGKRLL 139
S A+P ++ E L +K + + ++ GDT + D + G L G R L
Sbjct: 83 LLSAALP-ELDEVWLERFCGSFFGLAKKFGVTLIGGDTTKGDMAFNVTIIGELPKG-RAL 140
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREI----EEKARNPRARVEEGVKLSS 195
R A GD + V+G +G AL ++ +P ++ E+K P RV G+ L
Sbjct: 141 RRDAAVAGDDIWVSGRVGMAAAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLALLP 200
Query: 196 LANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIV--SDPVKVALASGEEF 253
A +A D+SDGL+++L I AS V I + LP +K+I+ + + LA G+++
Sbjct: 201 FARAAQDVSDGLAQDLGHILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDY 260
Query: 254 ELLFTIPR-------EKVEELDIDFKIIGRVEGGNGVYI--KRGRKIEELEVLGWEH 301
EL+FT P + E + IG++ GG + + GR++ EL LG++H
Sbjct: 261 ELVFTAPESCRSRVLDAAERCGVPVTRIGKINGGCRLKVLDADGREL-ELHSLGFDH 316
>dbj|BAB04263.1| (AP001508) thiamin-monophosphate kinase [Bacillus halodurans]
Length = 328
Score = 106 bits (261), Expect = 5e-22
Identities = 82/273 (30%), Positives = 140/273 (51%), Gaps = 22/273 (8%)
Query: 52 DFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYK 111
D +TP G K + +N+SD+AAMG P + S+AVP S+ ++ + RG+ E + Y+
Sbjct: 56 DTLTPFQIGYKSLAINISDLAAMGATPKFYLVSIAVPPQWSDREIKTLYRGMAECAAPYR 115
Query: 112 LKIVSGDTNEADDIII----DGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTAL-LLW 166
+ ++ GDT + ++ G + G R LLR A+PGD+V +TG +G+ L LL
Sbjct: 116 MDLIGGDTVSTNAKLVVTVTAVGHVPKGTR-LLRQRARPGDVVFLTGTVGQSAAGLELLN 174
Query: 167 MRGEKIPREIEEKA-----RNPRARVEEG--VKLSSLANSAIDISDGLSKELWEIANASN 219
+G P EE+ + P+ +VE G S + D+SDG++ E E+A AS
Sbjct: 175 KKGLHGPFTEEEELLVLAHQQPQPQVEAGHLFARSGYRIALNDVSDGVASEANELAEASK 234
Query: 220 VRIIIEEERLPISDSVKEIVSD-PVKVALASGEEFELLFTIPREKVEELD-------IDF 271
V+++++ +P+ +++ + ++ AL GE+F+L+ T + L I
Sbjct: 235 VKLVLKANTIPLHPAMETFSKEQQLEWALFGGEDFQLIGTAAVDAFASLQQLAIQRGISL 294
Query: 272 KIIGRVEGGNGVY-IKRGRKIEELEVLGWEHLA 303
IG VE G+ V ++ G L+ G+ H A
Sbjct: 295 TEIGYVEAGSPVVELEEGTARSVLKKSGYNHFA 327
>sp|Q58089|Y676_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION PROTEIN MJ0676
>gi|2127980|pir||D64384 hydrogenase expression/formation
protein homolog - Methanococcus jannaschii
>gi|1591391|gb|AAB98671.1| (U67515) hydrogenase
expression/formation protein (hypE) [Methanococcus
jannaschii]
Length = 335
Score = 101 bits (250), Expect = 9e-21
Identities = 77/254 (30%), Positives = 129/254 (50%), Gaps = 23/254 (9%)
Query: 25 DDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFS 84
DD+ I + + ++ T D T P F D GR V+ V+D+A MG +P+A S
Sbjct: 41 DDSATIPIGDKEIVFTVD---GHTVKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLS 97
Query: 85 LAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDT---NEADDIIIDGGSLGIGKR--LL 139
L +P + + L I + INE SK ++ I++GDT + DDIII +GI R +
Sbjct: 98 LIIPEGFNLEDLEKIVKSINETSKEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAI 157
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRG----EKIPREIEEKARNPRARVEEGVKLSS 195
N + GD + V+G++G A+LL G I ++ + +EEG+++++
Sbjct: 158 RDCNVQEGDAIIVSGNIGEHGLAILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINA 217
Query: 196 LANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS----DPVKVALASGE 251
+ + GL+ L E+A SN+ I I E+++PISD V+ I DP+ +A
Sbjct: 218 MKDPT---RGGLADALNEMAEKSNIGITIFEDKIPISDEVQSICDILGLDPLTIA----N 270
Query: 252 EFELLFTIPREKVE 265
E +++ + +E E
Sbjct: 271 EGKVVMAVKKEDAE 284
>gb|AAF18279.1| (AF088897) thiamin-monophosphate kinase [Zymomonas mobilis]
Length = 323
Score = 94.0 bits (230), Expect = 2e-18
Identities = 80/304 (26%), Positives = 141/304 (46%), Gaps = 30/304 (9%)
Query: 22 SLGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAF 81
+L DDA + + L+++ D++V PE +K+V +N+SD+AA G +P+
Sbjct: 25 NLSDDAAVLPRPSGDLVLSHDIIVENVHYFPSDPPETVAQKLVGVNLSDLAAKGAKPIGA 84
Query: 82 FFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTN---------EADDIIIDGGSL 132
++ D D + +G+ Y L ++ GDT A +I S
Sbjct: 85 LMGYSLGPDYKWD--QAFLKGLESVCHQYNLPLLGGDTVAVPRHTGHFSAMTVIGLAPSC 142
Query: 133 GIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKA----RNPRARVE 188
G+ R AK GD + VT +G L L + + I +EK R+P R++
Sbjct: 143 GVPDRRA----AKEGDELWVTSPIGDAGFGLNLLKQKKNINHSAQEKLVQAYRSPEPRLK 198
Query: 189 EGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVSDPVKV--- 245
EG+ L+ ++ DISDGL + IANAS + + I +R+P+S D
Sbjct: 199 EGIWLAPHVHAMADISDGLLIDAERIANASGLAVRIRLDRVPLSSEAISCFGDTKSTRLQ 258
Query: 246 ALASGEEFELLFTIPREKVEEL-------DIDFKIIGRVEGGNGVYIKRGRK-IEELEVL 297
A+ +G++++L+ K +EL D +G++ G+G+ + G + I++ + L
Sbjct: 259 AVTAGDDYQLIMACAANKRQELLKLSKEKQFDLYRVGQLTAGSGLSLFYGAEPIKQPDRL 318
Query: 298 GWEH 301
G+ H
Sbjct: 319 GYLH 322
>emb|CAC11666.1| (AL445064) thiamine monophosphate kinase related protein
[Thermoplasma acidophilum]
Length = 275
Score = 91.7 bits (224), Expect = 1e-17
Identities = 70/268 (26%), Positives = 121/268 (45%), Gaps = 16/268 (5%)
Query: 50 VPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKV 109
+PD P AGR + ++N+SDIAAM G P++F + +V D+ + L I G+ +
Sbjct: 1 MPDGTDPHLAGRFMASINLSDIAAMAGHPISFMTAYSVSPDLDMEYLEAIEEGMMSVLRK 60
Query: 110 YKLKIVSGDTNEADDIIIDGGSLGIGKRLLL--RSNAKPGDLVCVTGDLGRPLTALLLWM 167
Y + + GD E DD+ + G ++G + L RS+ G +V T +GR + + +
Sbjct: 61 YSVDFIGGDLKEGDDLTLVGIAIGRQTKKLTRKRSDIAKGQMVGYTNRIGRAASGYIFYK 120
Query: 168 RGEKIPREIEEKARNPRARVEEGVKLSSL-ANSAIDISDGLSKELWEIANASNVRIIIEE 226
G R + R+ E +K+S A +D+SDGL L ++ V I
Sbjct: 121 SGYDRKRGL-SMLLGVEPRISEAIKMSEYGARFMMDLSDGLYASLDQMKQDYGVGFRIVR 179
Query: 227 ERLPISDSVKEIV----SDPVKVALASGEEFELLFTIPREKVEELD-------IDFKIIG 275
+ + DSV + SD +A G ++E+LF++ ++ I+ IG
Sbjct: 180 DEIAYDDSVNKASEISGSDVYDIAGNYGGDYEILFSVDEANYKDFQAAMDSEHIEVHFIG 239
Query: 276 RVEGGNGVYIKRGRKIEELEVLGWEHLA 303
G+ + G + G+EH +
Sbjct: 240 ETWNGDNIMFD-GNAWHPIIGRGYEHFS 266
>pir||S74650 hypothetical protein slr1787 - Synechocystis sp. (strain PCC 6803)
>gi|1651875|dbj|BAA16802.1| (D90900) hypothetical
protein [Synechocystis sp.]
Length = 364
Score = 88.2 bits (215), Expect = 1e-16
Identities = 92/323 (28%), Positives = 151/323 (46%), Gaps = 28/323 (8%)
Query: 7 EGEIISLFMKHFERHSLGDDAGFIKLNNS-WLLVTSDMLVWKTDVPDFMTPE-DAGRKVV 64
E +++ K GDDA L NS L++++DMLV D T D G +
Sbjct: 41 EQALLAQLQKFSPAEITGDDAAVFDLPNSDSLVISTDMLVENVHFSDQTTSAFDVGWRGA 100
Query: 65 TMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADD 124
N+SD+AAMG P +LA+P + + +G+ + ++ I+ GD + +
Sbjct: 101 AANLSDLAAMGATPTGITVALALPPSTPLAWILDVYKGLTACLEPWRTPILGGDVSRSPL 160
Query: 125 IIIDGGSLG--IGKRLLLRSNAKPGDLVCVTGDLGRP---LTALLLWMRGEKIPRE---I 176
I LG + L R AK GD + TGD G L LL + E +P E I
Sbjct: 161 KTISITVLGQVPQGKALYRHQAKVGDWIIATGDHGTSRAGLECLLHPHKTEHLPPEQKLI 220
Query: 177 EEKA-RNPRARVEEGVKLSSLANS--AIDISDGLSKELWEIANASNVRIIIEEERLPISD 233
++A + P+ R++ L SL S A+D SDGL+ + +I AS + + E+LPI
Sbjct: 221 WQRAHQRPQPRLDLVPSLLSLETSIGAMDSSDGLADAVLQICRASQMGAELWAEKLPIPQ 280
Query: 234 SVKEIV--SDPVKVALASGEEFELLFTIPREKVEE-------LDI----DFKIIGRVEGG 280
+ + V + L GE+FEL+ IP + ++ LD+ ++IG++ G
Sbjct: 281 GLTDWVGLETAREWTLYGGEDFELILAIPPLEAQKWLMAIASLDLSPNRSPRVIGQITNG 340
Query: 281 NGV-YIKRGRKIEELEV-LGWEH 301
V + ++E+L + G++H
Sbjct: 341 TEVLLVLEEERVEKLSLQRGFQH 363
>pir||E82741 thiamin monophosphate kinase XF0956 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105884|gb|AAF83766.1|AE003934_8
(AE003934) thiamine-monophosphate kinase [Xylella
fastidiosa]
Length = 324
Score = 87.0 bits (212), Expect = 3e-16
Identities = 91/307 (29%), Positives = 140/307 (44%), Gaps = 37/307 (12%)
Query: 23 LGDDAGFIKL-NNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAF 81
+GDDA ++ L+VT+D L P PED G K + ++VSD+AAMG P
Sbjct: 24 VGDDAALLQPPQGEPLVVTTDTLNAGVHFPVETHPEDLGWKTLAVSVSDLAAMGATPRWC 83
Query: 82 FFSLAVPGDVSEDI--LRGIARGINEGSKVYKLKIVSGDTNEAD--DIIIDGGSLGIGKR 137
SL++ + D+ + A G E + ++ L +V GDT + G + G
Sbjct: 84 TLSLSL---LQADMAWIDAFADGFFELADLHGLVLVGGDTTYGPLATSVTAIGCVPPGMA 140
Query: 138 LLLRSNAKPGDLVCVTGDLGRPLTALLLWMRG-------EKIPR--EIEEKARNPRARVE 188
L R A GD + VTG G AL +W G PR + ++ P RVE
Sbjct: 141 LR-RDGACIGDDIWVTGRPGEAAAALAMWCAGMLDITKCAPDPRCEILRQRLLRPTPRVE 199
Query: 189 EGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS---DPVKV 245
G+ L L ++A+D+SDGL +L I +S V ++E LP + V D +V
Sbjct: 200 VGLGLRGLVHAAVDLSDGLLADLGHICASSGVGAVLECASLP-----RVAVHGGWDEAQV 254
Query: 246 A---LASGEEFELLFTIP-------REKVEELDIDFKIIGRVEGGNGVYIKRGRKIE-EL 294
A LA G+++EL FT ++ L ++ IGR+ G V + + +L
Sbjct: 255 ASWQLAGGDDYELCFTAAPQCGAPIQDMCANLGVEVTRIGRIVVGETVQVLNAAGVPWQL 314
Query: 295 EVLGWEH 301
G++H
Sbjct: 315 SRKGYQH 321
>pir||A81292 probable thiamin-phosphate kinase (EC 2.7.4.16) Cj1458c [imported]
- Campylobacter jejuni (strain NCTC 11168)
>gi|6968886|emb|CAB73881.1| (AL139078) putative
thiamin-monophosphate kinase [Campylobacter jejuni]
Length = 273
Score = 83.9 bits (204), Expect = 2e-15
Identities = 70/248 (28%), Positives = 118/248 (47%), Gaps = 28/248 (11%)
Query: 52 DFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYK 111
++ + E K + +N+SD +M P LA+P ++SE+ ++ + +G + ++ +
Sbjct: 42 EWFSLEQIATKAMLVNISDAISMNAVPKYALLGLALPKNLSENEIKALQKGFLKTARKFN 101
Query: 112 LKIVSGDTNEADDIIIDGGSLG-IGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGE 170
+KI+ GDT D I I + I + + R K G L+ TG LGR L L + G
Sbjct: 102 IKIIGGDTISNDKIDISLTIISKINDKAVFRKGLKKGHLLAYTGKLGRSLKGLEILQNGG 161
Query: 171 KI-PREIEEKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERL 229
+ P + K P+ R +++ L + A+DISDGLSK+L + + I
Sbjct: 162 TLKPNHVFIK---PKLRASFFYEIAPLISCAMDISDGLSKDLSRLLALNKCGI------- 211
Query: 230 PISDSVKEIVSDPVKVALASGEEFELLFTIPREKVEELDIDFK-------IIGRVEGGNG 282
S + + D AL SGEE+E+LF ++ + ++I K I G+ G
Sbjct: 212 ----SWFKKLDD---YALYSGEEYEILFAFDEKERQNIEIIAKKHGVKLNIFGKAV--KG 262
Query: 283 VYIKRGRK 290
Y RGR+
Sbjct: 263 KYEFRGRE 270
>sp|Q54757|THIL_SYNP7 THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|7469242|pir||T30275 hypothetical protein -
Synechococcus sp. (PCC 7942) >gi|1399826|gb|AAB82022.1|
(U59235) unknown [Synechococcus PCC7942]
Length = 327
Score = 82.7 bits (201), Expect = 5e-15
Identities = 85/298 (28%), Positives = 137/298 (45%), Gaps = 22/298 (7%)
Query: 24 GDDAGFIKLN-NSWLLVTSDMLVWKTDVPDFMTPEDA-GRKVVTMNVSDIAAMGGRPMAF 81
GDDA + L+V+SD+LV + TP A G + N+SD+AAMG P
Sbjct: 28 GDDAAILTPPAGQQLVVSSDVLVEGIHFSEATTPPAAIGWRAAAANLSDLAAMGATPAGI 87
Query: 82 FFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDGGSLG--IGKRLL 139
+LA+P D L+ I +G++ K Y ++ GD + + + +LG R++
Sbjct: 88 TLALALPSDRRLSWLQQIYQGLDRCLKQYDCPLIGGDLSRSPTATLAVTALGWVNPNRVI 147
Query: 140 LRSNAKPGDLVCVTGDLGRPLTAL--LL--WMRGEKIPRE--IEEKARNPRARVEEGVKL 193
RS A+ GD + TG G L LL W E + + +A PR V +
Sbjct: 148 RRSTAQVGDWIMATGTHGLSRLGLGHLLGEWTLAEPLRDQAIAAHQAPKPRLDVVPLLAR 207
Query: 194 SSLAN-----SAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVSDPVKVALA 248
S A + +D SDGL+ + +I AS V +IE LP + S ++ AL
Sbjct: 208 SQPAGTVWRVAGMDSSDGLADAVLQICRASQVGAVIEALPLPATTSFDR--DRLIQAALY 265
Query: 249 SGEEFELLFTI----PREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEV-LGWEH 301
GE+FEL+ + + +E L ++IG++ V ++ + E L + G++H
Sbjct: 266 GGEDFELVLCLSPDWAQALLELLGEQAQVIGQITEKPVVQLRLSDRTEILSLDRGFQH 323
>pir||D71121 probable hydrogenase expression/formation protein - Pyrococcus
horikoshii >gi|3257147|dbj|BAA29830.1| (AP000003) 336aa
long hypothetical hydrogenase expression/formation
protein [Pyrococcus horikoshii]
Length = 336
Score = 80.8 bits (196), Expect = 2e-14
Identities = 69/252 (27%), Positives = 110/252 (43%), Gaps = 17/252 (6%)
Query: 25 DDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFS 84
DD I L+ T D T P F D GR V+ V+D+A MG +P+A S
Sbjct: 40 DDGATIPFEGKHLVFTID---GHTVRPLFFPGGDIGRLAVSGTVNDLAVMGAKPLALASS 96
Query: 85 LAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADD---IIIDGGSLGIGKRLLLR 141
L + D L I + +N +K + I++GDT +D I + +GI ++ +
Sbjct: 97 LIIGEGFDSDKLEEILKSMNRTAKEVPVPIITGDTKVVEDNIEIFVITAGIGIAEKPISD 156
Query: 142 SNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKAR---NPRARVEEGVKLSSLAN 198
+ AK GDLV V G +G AL+ G E++ + V + + ++
Sbjct: 157 AGAKVGDLVLVNGTIGDHGIALMSHREGISFETELKSDVAPIWDVVKTVADAIGWENIHA 216
Query: 199 SAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKE----IVSDPVKVALASGEEFE 254
GLS L E+A ++V I++ E +PI VK + P VA E +
Sbjct: 217 MKDPTRGGLSNALNEMARKADVGILVRESDIPIRPEVKAAGDMLGISPYDVA----NEGK 272
Query: 255 LLFTIPREKVEE 266
++ + RE E+
Sbjct: 273 VIMVVDREYAED 284
>pir||E75040 hydrogenase expression/formation protein (hype) PAB0868 -
Pyrococcus abyssi (strain Orsay)
>gi|5458731|emb|CAB50218.1| (AJ248287) hydrogenase
expression/formation protein (hypE) [Pyrococcus abyssi]
Length = 336
Score = 80.4 bits (195), Expect = 3e-14
Identities = 69/252 (27%), Positives = 114/252 (44%), Gaps = 17/252 (6%)
Query: 25 DDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFS 84
DD I ++ ++ T D T P F D GR V+ V+D+A MG +P+A S
Sbjct: 40 DDGATIPIDGRHIVFTID---GHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASS 96
Query: 85 LAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADD---IIIDGGSLGIGKRLLLR 141
L + L I + ++E +K + IV+GDT ++ I + +GI ++ +
Sbjct: 97 LIIGEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISD 156
Query: 142 SNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKAR---NPRARVEEGVKLSSLAN 198
+ AK GD V V+G +G AL+ G E++ + V + + ++
Sbjct: 157 AGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHA 216
Query: 199 SAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKE----IVSDPVKVALASGEEFE 254
GLS L E+A +NV I+I+E +PI VK + P +VA E +
Sbjct: 217 MKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVA----NEGK 272
Query: 255 LLFTIPREKVEE 266
++ + RE EE
Sbjct: 273 VVMIVEREYAEE 284
>pir||B69125 hydrogenase expression/formation protein HypE - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621250|gb|AAB84711.1| (AE000807) hydrogenase
expression/formation protein HypE [Methanobacterium
thermoautotrophicum]
Length = 376
Score = 78.0 bits (189), Expect = 1e-13
Identities = 73/295 (24%), Positives = 135/295 (45%), Gaps = 30/295 (10%)
Query: 25 DDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFS 84
DD I L + +++++D T P F D GR V V+DI+ MG RP+A +
Sbjct: 81 DDGASIPLGDYEIVISTD---GHTIDPLFFPGGDIGRIAVAGTVNDISVMGARPLAIANA 137
Query: 85 LAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTN-----EADDIIIDGGSLGI-GKRL 138
+ + + L I + ++ S+ + IV+GDT + D ++I +G+ G+
Sbjct: 138 MIISEGFPGEDLERIIKSMDAVSRETGVSIVTGDTKVMEQGKLDRMVITTTGIGVVGRGE 197
Query: 139 LLR-SNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKARNPRARVEEGVKLSSLA 197
+R S +PGD + +TG +G AL+ + G ++E VE + + +
Sbjct: 198 TVRDSGLRPGDKIILTGSVGDHGMALMAFREGFGFDTDLESDVAPVWGIVEAALNVGGVT 257
Query: 198 NSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVS----DPVKVALASGEEF 253
G++ L E+A+ S V ++++E+ +P+ + VK + DP +VA E
Sbjct: 258 AMKDPTRGGIANALNEMADKSGVGMVLDEDSIPVREEVKAVSEMLGIDPYEVA----NEG 313
Query: 254 ELLFTIPREKVEEL---------DIDFKIIGRVEGGNGVYIKR---GRKIEELEV 296
+++ + E E++ + +IIG V V ++ GR+I E V
Sbjct: 314 KVIIGVDPEYAEDVLAAVRSAPYGEEARIIGEVTDDKHVILETSLGGRRILEAPV 368
>pir||A70388 hydrogenase expression/formation protein - Aquifex aeolicus
>gi|2983521|gb|AAC07097.1| (AE000719) hydrogenase
expression/formation protein [Aquifex aeolicus]
Length = 332
Score = 74.1 bits (179), Expect = 2e-12
Identities = 60/238 (25%), Positives = 112/238 (46%), Gaps = 17/238 (7%)
Query: 10 IISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDV----PDFMTPEDAGRKVVT 65
I +LF+K+F L KL ++ LL S + + TD P F D G+ V
Sbjct: 19 IKNLFLKYFSNEILN------KLEDASLLNLSGKVAFTTDAFTVSPIFFRGGDIGKLAVA 72
Query: 66 MNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDT-----N 120
V+D++ MG RP S + +S + L + + + + + ++IV+GDT
Sbjct: 73 GTVNDLSVMGARPKYLSVSFVIEEGLSFEELEEVVKSMAQEASKTGVQIVAGDTKVVPKG 132
Query: 121 EADDIIIDGGSLG-IGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEK 179
+AD + I +G + L N + G+++ V+G +G +L G + +E
Sbjct: 133 QADKLFISASGIGEVVYEGLSAHNLREGNVIIVSGSVGDHGACILAQREGMEFEVPVESD 192
Query: 180 ARNPRARVEEGVKLSSLANSAIDIS-DGLSKELWEIANASNVRIIIEEERLPISDSVK 236
++ +E+ + + ++ D + GL+ L E A S V I +EEE++P+ ++V+
Sbjct: 193 CKSLWNMIEKVLSSGAEVHAIRDATRGGLAGVLNEWAEQSKVTIEVEEEKIPVKEAVR 250
>emb|CAC02001.1| (AL390114) probable thiamine-monophosphate kinase [Leishmania
major]
Length = 321
Score = 71.8 bits (173), Expect = 1e-11
Identities = 75/261 (28%), Positives = 119/261 (44%), Gaps = 25/261 (9%)
Query: 23 LGDDAGFIKLNNSWLL-VTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAF 81
+GDD + LL V++DMLV + P G K + +N+SD+AAMG P AF
Sbjct: 26 VGDDCALLDPRPGHLLAVSTDMLVIGRHFFPDVPPRALGHKALAVNLSDLAAMGAEPRAF 85
Query: 82 FFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDGGSLGIGKR--LL 139
+LA+P + L +A G+ E + + ++V GDT + + G R L
Sbjct: 86 TLALALP-EAEPAWLAELAAGMLELADAHGCELVGGDTTRG-PLTLSLTVFGDVPRGSAL 143
Query: 140 LRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIE-----------EKARNPR-ARV 187
R A+PGD + ++G LG A L RGE + E + + AR R
Sbjct: 144 RRDAARPGDDIWISGTLGDARLA-LGDCRGEWLLPEPDFTLGASAHGYADAARXARHGAA 202
Query: 188 EEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVSD-PVKVA 246
G + S++ + G S +L I S V +++ + LP ++ + D ++
Sbjct: 203 RAGPRGRSISRT------GXSXDLGHIXERSQVGALLDVDALPRTEVLASQPRDCQLECV 256
Query: 247 LASGEEFELLFTIPREKVEEL 267
LA G+++EL FT P E L
Sbjct: 257 LAGGDDYELCFTAPAGAREAL 277
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.140 0.396
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118770919
Number of Sequences: 2977
Number of extensions: 5148380
Number of successful extensions: 12511
Number of sequences better than 1.0e-10: 34
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 12429
Number of HSP's gapped (non-prelim): 34
length of query: 310
length of database: 189,106,746
effective HSP length: 56
effective length of query: 254
effective length of database: 155,591,474
effective search space: 39520234396
effective search space used: 39520234396
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)