BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB2359 (korA-1) DE:2-ketoglutarate ferredoxin oxidoreductase,
subunit alpha (korA-1)
         (408 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp...   837  0.0
pir||B71047 probable ferredoxin oxidoreductase alpha subunit - P...   790  0.0
pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp...   437  e-121
pir||F71046 probable ferredoxin oxidoreductase alpha subunit - P...   435  e-121
sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET...   373  e-102
pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7....   358  7e-98
sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET...   358  7e-98
pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7....   351  9e-96
pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7....   282  6e-75
gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit a...   279  4e-74
pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   268  1e-70
pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacte...   266  3e-70
gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:accepto...   257  2e-67
pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (s...   246  4e-64
dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Baci...   204  1e-51
sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB...   202  5e-51
pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   202  5e-51
gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, su...   200  2e-50
pir||F70864 probable oxidoreductase alpha subunit - Mycobacteriu...   190  3e-47
emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit...   186  3e-46
emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces...   186  3e-46
pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha ...   180  3e-44
pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validate...   176  4e-43
gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin ox...   176  4e-43
emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidore...   176  4e-43
emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidored...   168  1e-40
pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha...   167  2e-40
gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain...   162  5e-39
pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit -...   153  4e-36
pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   143  4e-33
pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   141  2e-32
emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma a...   138  2e-31
gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (...   123  3e-27
pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase...   113  4e-24
sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA...   109  7e-23
pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 -...   108  2e-22
pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit -...   107  2e-22
sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   106  4e-22
pir||A71114 probable ferredoxin oxidoreductase alpha subunit - P...   106  5e-22
sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA...   106  6e-22
dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase al...   106  6e-22
sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   104  3e-21
sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   103  3e-21
gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...   100  4e-20
emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin ox...    99  1e-19
pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex ae...    98  2e-19
gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...    97  4e-19
gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit...    96  6e-19
gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alph...    96  9e-19
pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex ae...    94  2e-18
pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicob...    94  3e-18
pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter py...    93  5e-18
gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alp...    92  1e-17
emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin ox...    83  5e-15
sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...    83  5e-15
gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta s...    77  4e-13
gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...    76  9e-13
pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolo...    76  9e-13
pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alph...    71  3e-11
sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA ...    69  9e-11

>pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha  (kora-1)
           PAB2359 - Pyrococcus abyssi (strain Orsay)
           >gi|5457936|emb|CAB49426.1| (AJ248284) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA-1)
           [Pyrococcus abyssi]
           Length = 408
           
 Score =  837 bits (2138), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI 60
           MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI
Sbjct: 1   MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI 60

Query: 61  TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL 120
           TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL
Sbjct: 61  TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL 120

Query: 121 GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE 180
           GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE
Sbjct: 121 GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE 180

Query: 181 TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH 240
           TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH
Sbjct: 181 TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH 240

Query: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE 300
           GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE
Sbjct: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE 300

Query: 301 YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360
           YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI
Sbjct: 301 YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360

Query: 361 LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA 408
           LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA
Sbjct: 361 LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA 408


>pir||B71047 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3258095|dbj|BAA30778.1| (AP000006) 408aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 408
           
 Score =  790 bits (2018), Expect = 0.0
 Identities = 376/408 (92%), Positives = 398/408 (97%)

Query: 1   MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI 60
           M R C+S KVV MIIRGDEPEQK LLRKLY+PGNYFMMGDEA+AYGAIFAGCRFYAGYPI
Sbjct: 1   MSRLCNSRKVVVMIIRGDEPEQKALLRKLYRPGNYFMMGDEAIAYGAIFAGCRFYAGYPI 60

Query: 61  TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL 120
           TPSSEIAETMARELPKVGGYYLQMEDEI SIAAM+GASWTGLK MTATSGPGFSLMQEN+
Sbjct: 61  TPSSEIAETMARELPKVGGYYLQMEDEIGSIAAMIGASWTGLKAMTATSGPGFSLMQENI 120

Query: 121 GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE 180
           GYAVMTETP+V+V+VQRSGPSTGQATKGAQGDFFQARWGTHGDHP++A+SP+SVEDAFWE
Sbjct: 121 GYAVMTETPIVVVNVQRSGPSTGQATKGAQGDFFQARWGTHGDHPMIAVSPISVEDAFWE 180

Query: 181 TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH 240
           TIRAFN+AE+LRTPV+VLFDGILGHTREQIRIPDPDEVEI YRKLP +EEEA+LPFGDPH
Sbjct: 181 TIRAFNIAEKLRTPVIVLFDGILGHTREQIRIPDPDEVEITYRKLPGSEEEAKLPFGDPH 240

Query: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE 300
           GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNR+VYEKYEE
Sbjct: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNRDVYEKYEE 300

Query: 301 YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360
           YYTDDAEILVVSWGVSARPSLGAVLKAR+EGIK GLFVPKTVHPFPGERMRELGKKVRAI
Sbjct: 301 YYTDDAEILVVSWGVSARPSLGAVLKAREEGIKAGLFVPKTVHPFPGERMRELGKKVRAI 360

Query: 361 LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA 408
           LVPEMNLGQM+LEVQRFVNDDV+LKGVNKIGGVPLTVEEIL+EIRGVA
Sbjct: 361 LVPEMNLGQMVLEVQRFVNDDVILKGVNKIGGVPLTVEEILKEIRGVA 408


>pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha  (kora-2)
           PAB0346 - Pyrococcus abyssi (strain Orsay)
           >gi|5457939|emb|CAB49429.1| (AJ248284) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA-2)
           [Pyrococcus abyssi]
           Length = 385
           
 Score =  437 bits (1111), Expect = e-121
 Identities = 217/370 (58%), Positives = 273/370 (73%)

Query: 36  FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95
           F+ GDEA+A  AI AGCRFYAGYPITP+SEI E MA  +P V G  +QMEDEIASIAA++
Sbjct: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71

Query: 96  GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155
           GASW G K MTATSGPGFSLMQEN+GYAVMTETP+V+VDVQR GPSTGQ T  +QGD  Q
Sbjct: 72  GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131

Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215
           + WGTHGDH ++ +SP +V++AF  TIRAFN+AE+ RTPV++L D  +GH RE++ IP+P
Sbjct: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191

Query: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275
           DE+EIV RKLPQNEEEA+LPFGDPHGD VPPMP+FG GY T+VTG TH E G      +E
Sbjct: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251

Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335
           VH++++RRI  KIE+N++    YE    DDAE+ +V+ G+ AR +L A+ + R+ GIK G
Sbjct: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311

Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395
           L    T+ PF  E + ++  KV  I VPEMNLGQ+   V+   N    +K ++KIGG   
Sbjct: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371

Query: 396 TVEEILREIR 405
           T  EI+  IR
Sbjct: 372 TPMEIVDFIR 381


>pir||F71046 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3258091|dbj|BAA30774.1| (AP000006) 385aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 385
           
 Score =  435 bits (1107), Expect = e-121
 Identities = 215/370 (58%), Positives = 273/370 (73%)

Query: 36  FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95
           F+ GDEA+A  AI AGCRFYAGYPITP+SEI E MA  +P + G  +QMEDEI SIAA++
Sbjct: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLIDGVVIQMEDEIGSIAAVI 71

Query: 96  GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155
           GASW G+K MTATSGPGFSLMQEN+GYAVMTETP+V+V+VQR GPSTGQ T  +QGD  Q
Sbjct: 72  GASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRGGPSTGQPTLPSQGDIMQ 131

Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215
           + WGTHGDH ++ +SP +V++AF  TIRAFN+AE+ RTPV++L D  +GH RE++ IP+P
Sbjct: 132 SIWGTHGDHTLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191

Query: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275
           DE+EIV RKLP +EEEA+LPFGDPHGDGVPPMP+FG GY T+VTG TH E G      +E
Sbjct: 192 DEIEIVNRKLPGSEEEAKLPFGDPHGDGVPPMPIFGKGYRTYVTGLTHDEKGRPRTVERE 251

Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335
           VH++L+RRI  KIE+N++    YE    DDAEI +V+ G+ AR +L A+ + R  GIK G
Sbjct: 252 VHERLIRRIFEKIEKNKKDIFDYEARELDDAEIAIVTTGIVARSALRAIKELRNLGIKAG 311

Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395
           L    T+ PF  E + ++ +KV  I VPEMNLGQ+   V+   N    +K ++KIGG   
Sbjct: 312 LLKINTIWPFDFELIEKVAEKVERIYVPEMNLGQLYHLVKEGANGKAEVKLISKIGGEVH 371

Query: 396 TVEEILREIR 405
           T  EI+  IR
Sbjct: 372 TPMEIIDFIR 381


>sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
           OXIDOREDUCTASE ALPHA CHAIN) (KOR)
           (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           >gi|2127893|pir||E64334 2-oxoacid--ferredoxin
           oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus
           jannaschii >gi|1592279|gb|AAB98264.1| (U67483)
           2-ketoglutarate ferredoxin oxidoreductase, subunit alpha
           (korA) [Methanococcus jannaschii]
           Length = 366
           
 Score =  373 bits (948), Expect = e-102
 Identities = 200/373 (53%), Positives = 263/373 (69%), Gaps = 13/373 (3%)

Query: 36  FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95
           FM G++A A GAI AGCRF+AGYPITPS+EIAE MARELPKVGGYY+QMEDEI SIAA++
Sbjct: 5   FMQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELPKVGGYYIQMEDEIGSIAAVI 64

Query: 96  GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155
           GASW GLK MTATSGPGFSLMQEN+G+A MTETP V+VD+QR GPSTGQ T  +QGD  Q
Sbjct: 65  GASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQRGGPSTGQPTMASQGDMMQ 124

Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215
            RWG+HGD+ ++A++P SV++ +  TI AFN AE+ R PV V+ D I+GH RE++ +   
Sbjct: 125 CRWGSHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRIPVFVMADEIVGHMREKVIL--H 182

Query: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275
           D +EI+ RK P+ E+  + P+  P    +P MP+FG GY  H+TG TH E G  DV + E
Sbjct: 183 DNIEIINRKKPE-EKPCKKPY--PFDKLIPEMPVFGEGYNVHITGLTHDERGYPDV-SPE 238

Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335
            HDKLVRRI  KI +N++   K+E     DAEI+ V +G  +R    AV   R++G+ VG
Sbjct: 239 THDKLVRRIVNKIRKNKDEIIKWEGENL-DAEIVFVCYGSPSRTVKHAVRNLREKGLDVG 297

Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVN--DDVLLKGVNKIGGV 393
                TV+PFP + +++L  K + ++VPEMNLGQ+  EV+R     ++V+L  V+KIGG 
Sbjct: 298 YIRLITVYPFPDDLLKKL--KAKKVVVPEMNLGQIYYEVERVCKKAEEVIL--VDKIGGE 353

Query: 394 PLTVEEILREIRG 406
               EE+ R + G
Sbjct: 354 LHRPEELERAVLG 366


>pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           - Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622136|gb|AAB85529.1| (AE000875) 2-oxoglutarate
           oxidoreductase, alpha subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 378
           
 Score =  358 bits (909), Expect = 7e-98
 Identities = 191/370 (51%), Positives = 247/370 (66%), Gaps = 3/370 (0%)

Query: 35  YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAM 94
           YF+ G++A A GAI AGCRF+AGYPITPS+EIAE MA  LP+ GG ++QMEDEI ++ A+
Sbjct: 7   YFIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAV 66

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
           +GA W+G++ MTATSGPGFSLMQE++GYA MTETPLV+V+VQR  PSTGQ T  +Q D  
Sbjct: 67  IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 126

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD 214
           QARWG+HGD+ I+A+SP SV++ F  T+RAFN+AE  R PV+V+ D I+GH RE+I I  
Sbjct: 127 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI-- 184

Query: 215 PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQ 274
           PD V+I  R+ P    E  LPF  P  DGVP MP FG GY   VTG TH E G  D    
Sbjct: 185 PDRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNP 243

Query: 275 EVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKV 334
           E H +LV+R+  KI ++R+     +E  T+DA I V+S+G  +R    AV  AR++G++ 
Sbjct: 244 EGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRA 303

Query: 335 GLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVP 394
           G     T  PFP   +R   ++   +LV EMNLGQM  EVQR       ++ + KIGG  
Sbjct: 304 GYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEI 363

Query: 395 LTVEEILREI 404
              EEIL  I
Sbjct: 364 HRPEEILNMI 373


>sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
           OXIDOREDUCTASE ALPHA CHAIN) (KOR)
           (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           Length = 376
           
 Score =  358 bits (909), Expect = 7e-98
 Identities = 191/370 (51%), Positives = 247/370 (66%), Gaps = 3/370 (0%)

Query: 35  YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAM 94
           YF+ G++A A GAI AGCRF+AGYPITPS+EIAE MA  LP+ GG ++QMEDEI ++ A+
Sbjct: 5   YFIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAV 64

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
           +GA W+G++ MTATSGPGFSLMQE++GYA MTETPLV+V+VQR  PSTGQ T  +Q D  
Sbjct: 65  IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 124

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD 214
           QARWG+HGD+ I+A+SP SV++ F  T+RAFN+AE  R PV+V+ D I+GH RE+I I  
Sbjct: 125 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI-- 182

Query: 215 PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQ 274
           PD V+I  R+ P    E  LPF  P  DGVP MP FG GY   VTG TH E G  D    
Sbjct: 183 PDRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNP 241

Query: 275 EVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKV 334
           E H +LV+R+  KI ++R+     +E  T+DA I V+S+G  +R    AV  AR++G++ 
Sbjct: 242 EGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRA 301

Query: 335 GLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVP 394
           G     T  PFP   +R   ++   +LV EMNLGQM  EVQR       ++ + KIGG  
Sbjct: 302 GYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEI 361

Query: 395 LTVEEILREI 404
              EEIL  I
Sbjct: 362 HRPEEILNMI 371


>pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           TM0878 [similarity] - Thermotoga maritima (strain MSB8)
           >gi|4981412|gb|AAD35959.1|AE001753_15 (AE001753)
           pyruvate:ferredoxin 2-oxidoreductase-related protein
           [Thermotoga maritima]
           Length = 386
           
 Score =  351 bits (891), Expect = 9e-96
 Identities = 191/374 (51%), Positives = 247/374 (65%), Gaps = 5/374 (1%)

Query: 32  PGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASI 91
           P   F+ G+EA A GAI AGCRF+AGYPITPS+EIAE MARELPKVGG ++QMEDEIAS 
Sbjct: 4   PEMMFLQGNEACALGAIKAGCRFFAGYPITPSTEIAEVMARELPKVGGVFVQMEDEIASA 63

Query: 92  AAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQG 151
           AA+VGAS  G+K MTATSGPGFSL+QE +GYA+MTETP V  +V R GPSTG  TK AQG
Sbjct: 64  AAVVGASLAGVKSMTATSGPGFSLIQEVIGYAIMTETPCVFANVMRLGPSTGLPTKPAQG 123

Query: 152 DFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIR 211
           D  Q RWGTHGDH I+A+ P SV + +   I AFN+AE  RTPVV L D +LGH RE   
Sbjct: 124 DIMQTRWGTHGDHAIIALYPSSVAEVYRYIITAFNLAEEYRTPVVFLMDAMLGHMRESFY 183

Query: 212 IPDPDEVEIVYRKLPQN--EEEARLPFGDPHGDGVPPMPLFGHGYFT-HVTGSTHKENGL 268
            P  +E+ I+ R    +  EE+  +PF +       P P+   G    HV+G  H E+G 
Sbjct: 184 PPKDEELFIIERLKDTSFGEEDLFVPFSESEYAEPTPFPMAEMGKTKFHVSGLVHDESGF 243

Query: 269 RDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAR 328
             + + +  +KL+RR+  KI  + +    YEEY T+DAEILVV++G+ AR ++ AV  AR
Sbjct: 244 -PLSSPDAAEKLIRRLTNKIRLHADEIAFYEEYETEDAEILVVAYGIVARSAMKAVKIAR 302

Query: 329 KEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILE-VQRFVNDDVLLKGV 387
           ++ IKVGLF P T+ P P  R R+L +KV  I++ EMNLGQ   E +        +++ +
Sbjct: 303 RDRIKVGLFKPITIWPAPVSRFRKLAEKVNTIVIAEMNLGQYAKELISSIDRRSKVIRTI 362

Query: 388 NKIGGVPLTVEEIL 401
           NK+ G  +  EEIL
Sbjct: 363 NKVNGELIKPEEIL 376


>pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           Cj0536 [similarity] - Campylobacter jejuni (strain NCTC
           11168) >gi|6968004|emb|CAB75172.1| (AL139075) OORA
           subunit of 2-oxoglutarate:acceptor oxidoreductase
           [Campylobacter jejuni]
           Length = 374
           
 Score =  282 bits (713), Expect = 6e-75
 Identities = 148/367 (40%), Positives = 230/367 (62%), Gaps = 3/367 (0%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G+  +A  AI  GC+F+ GYPITPSSEIA  ++  LP   G ++QMEDEI+ I+  +GA+
Sbjct: 8   GNVLIAKAAIDCGCKFFGGYPITPSSEIAHELSHMLPANDGTFIQMEDEISGISVAIGAA 67

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
            +G+K MTA+SGPG SL  E +G A + E PLV+V+V R GPSTG  T+ AQGD FQA+ 
Sbjct: 68  MSGVKSMTASSGPGISLKAEQIGLAFIAEIPLVIVNVMRGGPSTGLPTRVAQGDLFQAKA 127

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218
            THGD   +AI+P S+E+A+ ETIRAFN+AE+  TPV +L D  +GH   +  +PD  ++
Sbjct: 128 PTHGDFASIAIAPASLEEAYTETIRAFNLAEKYMTPVFLLMDETVGHMNGKAVLPDLKDI 187

Query: 219 EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHD 278
           ++  RK  + +++   P+     +     P F  GY  HVTG  H + G        +  
Sbjct: 188 KVYNRKKFEGDKKDYKPYAAGENEPATLNPFF-TGYRYHVTGLHHGDIGF-PTEDGVIVK 245

Query: 279 KLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFV 338
           K + R+  KI+ N+E    YEEY  DDAE L++++G  +R +  A+ + R++GIKVGLF 
Sbjct: 246 KNMERLIGKIKNNQEDICTYEEYMLDDAEFLIIAYGSVSRSAKEAIQRLREQGIKVGLFR 305

Query: 339 PKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVE 398
           P T++P   +++ E+  K + ++V E+N+GQ + E++R  +    +  +++  G P+T  
Sbjct: 306 PITLYPVAEKKIAEVVSKFKKVMVSELNMGQYLEEIERVTSRRDFI-SLHRANGRPITPS 364

Query: 399 EILREIR 405
           EI+ +++
Sbjct: 365 EIIAKVK 371


>gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA)
           [Archaeoglobus fulgidus]
           >gi|6685587|sp|O29781|KORA_ARCFU 2-OXOGLUTARATE SYNTHASE
           SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA
           CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE
           ALPHA SUBUNIT) >gi|7433685|pir||E69308
           2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain korA - Archaeoglobus fulgidus
           >gi|2650159|gb|AAB90768.1| (AE001072) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA)
           [Archaeoglobus fulgidus]
           Length = 346
           
 Score =  279 bits (706), Expect = 4e-74
 Identities = 157/370 (42%), Positives = 224/370 (60%), Gaps = 31/370 (8%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96
           + G+EA   GAI AGC F+AGYPITPSSEIA  MA  LPK GG ++QMEDEIASI+A++G
Sbjct: 6   IQGNEAAVRGAINAGCNFFAGYPITPSSEIAHGMAELLPKFGGVFIQMEDEIASISAVIG 65

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156
           AS  G   MTATSGPGFSLMQE +GYA +TE+P+V+ +V R+GPSTG  T  +QGD  QA
Sbjct: 66  ASMAGAVAMTATSGPGFSLMQEGMGYAAITESPVVIFNVMRAGPSTGIPTAPSQGDAMQA 125

Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPD 216
           R+G+HGD+PIV ++P SV+D ++ T+ AF +A R  TPV+VL D I+GH RE + +P   
Sbjct: 126 RYGSHGDYPIVVLAPASVKDMYYLTVEAFKIAFRFSTPVIVLSDEIVGHMRESVALPPLG 185

Query: 217 EVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276
           E+E  Y K  +N  + R                       H TG  H ENGL     +E 
Sbjct: 186 EIE-SYEKRAKNLIDGRR---------------------RHRTGLVHTENGLPTTDLEE- 222

Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGL 336
           ++KL+R +  K +  R +       +  +  +L V++G S R +  +     ++G+  G+
Sbjct: 223 YEKLLRLLFAKFDDFRPMVR-----FEGEEGVLFVAYGSSYRLAKSSAKLLAEKGVSAGI 277

Query: 337 FVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLT 396
              +++ PFP + +R   KK   ++VPEMN GQ++ EV+R     V  KGV+  G + L 
Sbjct: 278 LKLESLFPFPEDAVRRYSKKADLVVVPEMNAGQVVKEVERVCCCRV--KGVSYFGSLILP 335

Query: 397 VEEILREIRG 406
            E+++  + G
Sbjct: 336 -EKLVEIVEG 344


>pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Helicobacter pylori (strain 26695)
           >gi|2313707|gb|AAD07654.1| (AE000572) ferredoxin
           oxidoreductase, alpha subunit [Helicobacter pylori
           26695]
           Length = 375
           
 Score =  268 bits (677), Expect = 1e-70
 Identities = 152/370 (41%), Positives = 224/370 (60%), Gaps = 7/370 (1%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G+E VA  AI  GCRF+ GYPITPSS+I   M+  LPK GG+++QMEDEI+ I+  +GAS
Sbjct: 8   GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
            +G K MTA+SGPG SL  E +GY+ M E PLV+ DV RSGPSTG  T+ AQGD    R 
Sbjct: 68  MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218
             HGD   VA++P ++E+A+ ET+RAFN+AE L TPV +L D  +GH   +++IPD +EV
Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187

Query: 219 E--IVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276
           +   + RK    +++   P+G    +     P F  GY  HV+G  H   G       ++
Sbjct: 188 QKMTINRKEFLGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGF-PTEDAKI 245

Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG-IKVG 335
              L+ R+  KIE  +++  + EE   + AEI+V+++G  +     A+    KE   KVG
Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVVIAYGSVSLAVKEALKDYHKESKQKVG 305

Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395
            F PKT+ P P +R++E+G K   ILV E+N GQ + E++R +   V   G  +  G  +
Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERAMQRKVHFLG--QANGRTI 363

Query: 396 TVEEILREIR 405
           + ++I+ +++
Sbjct: 364 SPKQIIAKLK 373


>pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacter pylori
           (strain J99) >gi|4155084|gb|AAD06119.1| (AE001486)
           SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE [Helicobacter
           pylori J99]
           Length = 375
           
 Score =  266 bits (673), Expect = 3e-70
 Identities = 150/370 (40%), Positives = 223/370 (59%), Gaps = 7/370 (1%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G+E VA  AI  GCRF+ GYPITPSS+I   M+  LPK GG+++QMEDEI+ I+  +GAS
Sbjct: 8   GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
            +G K MTA+SGPG SL  E +GY+ M E PLV+ DV RSGPSTG  T+ AQGD    R 
Sbjct: 68  MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218
             HGD   VA++P ++E+A+ ET+RAFN+AE L TPV +L D  +GH   +++IPD +EV
Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187

Query: 219 E--IVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276
           +   + RK    +++   P+G    +     P F  GY  HV+G  H   G       ++
Sbjct: 188 QKMTINRKEFAGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGF-PTEDAKI 245

Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG-IKVG 335
              L+ R+  KIE  +++  + EE   +  EI+++++G  +     A+    KE   KVG
Sbjct: 246 GGDLIDRLFHKIESKQDIINENEEMDLEGTEIVIIAYGSVSLAVKEALKDYNKESKQKVG 305

Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395
            F PKT+ P P +R++E+G K   ILV E+N GQ + E++R +   V   G  +  G  +
Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERVMQRKVHFFG--QANGRTI 363

Query: 396 TVEEILREIR 405
           + ++I+ +++
Sbjct: 364 SPKQIIAKLK 373


>gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:acceptor oxidoreductase
           [Helicobacter pylori]
           Length = 371
           
 Score =  257 bits (649), Expect = 2e-67
 Identities = 144/340 (42%), Positives = 206/340 (60%), Gaps = 5/340 (1%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G+E VA  AI  GCRF+ GYPITPSS+I   M+  LP  GG+++QMEDEI+ I+  +GAS
Sbjct: 8   GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPNCGGHFIQMEDEISGISVSLGAS 67

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
            +G K MTA+SGPG SL  E +GY+ M E PLV+ DV RSGPSTG  T+  QGD    R 
Sbjct: 68  MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVDQGDVNFLRH 127

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218
             HGD   VA++P S+E+A+ ET RAFN+AE L TPV +L D  +GH   +++IPD +EV
Sbjct: 128 PIHGDFKAVALAPASLEEAYTETARAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187

Query: 219 E--IVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276
           +   + RK    +++   P+G    +     P F  GY  HV+G  H   G       ++
Sbjct: 188 QKTTINRKEFVGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGF-PTEDAKI 245

Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE-GIKVG 335
              L+ R+  KIE  +++  + EE   + AEI+++++G  +     A+    KE   KVG
Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVIIAYGSVSLAVKEALKDYHKESNQKVG 305

Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQ 375
            F PKT+ P P +R++E+G K   ILV E+N GQ + +++
Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLKKLK 345


>pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8)
           >gi|4982338|gb|AAD36824.1|AE001814_6 (AE001814)
           2-oxoisovalerate oxidoreductase, beta subunit, putative
           [Thermotoga maritima]
           Length = 356
           
 Score =  246 bits (621), Expect = 4e-64
 Identities = 150/380 (39%), Positives = 209/380 (54%), Gaps = 46/380 (12%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96
           M G+EA+A  AI AGCR Y  YPITP SEIAE MAR LP+VGG +LQ E EIA++  + G
Sbjct: 9   MKGNEAIAESAIRAGCRLYFAYPITPQSEIAEYMARRLPEVGGVFLQTESEIATVNMVYG 68

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156
           A+ TG +VMT+TS PGFSLMQE + Y    E P V VDV R GP  G   + +QGD+FQA
Sbjct: 69  AACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGN-IQPSQGDYFQA 127

Query: 157 -RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD- 214
            + G HGD+ ++ ++P ++++A   T  AF++A+R R PV++L DG++G   E + +P+ 
Sbjct: 128 VKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLADRYRNPVLILADGMIGQMMEPVELPEM 187

Query: 215 ------PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGL 268
                 PD  +   R     E      F       + P+ L                   
Sbjct: 188 RDLSTLPDHSDWALRGARNREPHRIAAF------NIDPVGL------------------- 222

Query: 269 RDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAR 328
                    +K+ +R+  K        +++EEY  D AE L+V +G   R     V   R
Sbjct: 223 ---------EKMNKRLQEKYRLIEASEQRWEEYRVDGAEYLMVGYGTMGRILKSVVDSLR 273

Query: 329 KEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVN 388
           +EGI  GLF P T+ PFP  R++EL KKV+ I V EM+ GQM+ +VQ  V   V +    
Sbjct: 274 EEGIPAGLFRPVTLWPFPKRRLKELAKKVQLIFVVEMSSGQMVEDVQISVEGKVPVHFYG 333

Query: 389 KIGGVPLTVEEIL---REIR 405
           ++GGV  T EEIL   +E+R
Sbjct: 334 RMGGVVPTPEEILFAFKEVR 353


>dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Bacillus halodurans]
           Length = 579
           
 Score =  204 bits (514), Expect = 1e-51
 Identities = 125/374 (33%), Positives = 199/374 (52%), Gaps = 10/374 (2%)

Query: 36  FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95
           FM+G++A+  GA+ AG RF A YPITP+SEI E + ++LP+ GG  +Q EDEIA+    +
Sbjct: 199 FMIGNDAIGMGAVAAGSRFMAAYPITPASEIMEYLIKKLPEFGGAVIQTEDEIAACTMAI 258

Query: 96  GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155
           GA++ G++  TA++GPG SLM E +G + MTETPLV+VD QR GPS G  TK  Q D   
Sbjct: 259 GANYAGVRSFTASAGPGLSLMAEAIGLSGMTETPLVIVDTQRGGPSIGLPTKQEQSDLMA 318

Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215
             + THGD P V ++P +VE+AF++T+ AFN+AE  + PV+++ D  L   ++ +   D 
Sbjct: 319 MIYSTHGDIPKVVMAPSTVEEAFYDTVEAFNIAEEYQCPVILVTDLALSLGKQTVEPLDF 378

Query: 216 DEVEIVYRKLPQNEEEARLPFGDPH------GDGVPPMPLFGH-GYFTHVTGSTHKENGL 268
            +VEI    L   ++      G+ +        GV P  L G      HVTG  H + G 
Sbjct: 379 SKVEIRRGSLQNEDQLTEQEKGEYYKRYELTETGVSPRVLPGQKNGIHHVTGVEHDQTGK 438

Query: 269 RDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYT--DDAEILVVSWGVSARPSLGAVLK 326
                    +++ +R+ RK+E   E +      +   ++ ++LV+    +      A+ +
Sbjct: 439 PSESATNRIEQMEKRL-RKVEALPERFPTPVHIHAPHEEPDLLVIGINSTRGAIEEAIPR 497

Query: 327 ARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKG 386
              + I+V     + VHPFP   ++    K + ++V E N    +  + +   D   ++ 
Sbjct: 498 LEADSIRVNHAHIRLVHPFPKHELQPYLTKAKKVVVVEHNATAQLASLIKMNCDVKAIEN 557

Query: 387 VNKIGGVPLTVEEI 400
           V +  G P    EI
Sbjct: 558 VLRYDGNPFLPGEI 571


>sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE BETA SUBUNIT)
           Length = 352
           
 Score =  202 bits (509), Expect = 5e-51
 Identities = 134/371 (36%), Positives = 200/371 (53%), Gaps = 32/371 (8%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G+ AV  GA++AGC  Y GYPITP+SEI    +R  P VG  ++Q E E A+I  + GA+
Sbjct: 8   GNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAA 67

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ-AR 157
             G +VMTA+SGPG SL QE + +    E P V+VDV R+GP  G      QGD+ Q  +
Sbjct: 68  AAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGP-EQGDYNQIVK 126

Query: 158 WGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDE 217
            G HG++  + ++P SV++    T+ AF +A++ R PVVVL D +LG   E +R P+ + 
Sbjct: 127 GGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPE-EA 185

Query: 218 VEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVH 277
           VE                    H                ++  S   +    + +   + 
Sbjct: 186 VE--------------------HRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQ 225

Query: 278 DKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLF 337
           +K  R     IE+N     +YEEY  DDAEI++V++G+S+R +  AV  AR EGI VGL 
Sbjct: 226 EKYAR-----IEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLL 277

Query: 338 VPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTV 397
            P T+ PFP +R+REL       +  EM+ GQM  ++ R  +    ++ VN++GG  + +
Sbjct: 278 RPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDI-RMASGCRDVELVNRMGGNLIEL 336

Query: 398 EEILREIRGVA 408
            ++L +IR VA
Sbjct: 337 RDVLEKIREVA 347


>pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621790|gb|AAB85209.1| (AE000849) 2-oxoisovalerate
           oxidoreductase, beta subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 348
           
 Score =  202 bits (509), Expect = 5e-51
 Identities = 134/371 (36%), Positives = 200/371 (53%), Gaps = 32/371 (8%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G+ AV  GA++AGC  Y GYPITP+SEI    +R  P VG  ++Q E E A+I  + GA+
Sbjct: 4   GNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAA 63

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ-AR 157
             G +VMTA+SGPG SL QE + +    E P V+VDV R+GP  G      QGD+ Q  +
Sbjct: 64  AAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGP-EQGDYNQIVK 122

Query: 158 WGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDE 217
            G HG++  + ++P SV++    T+ AF +A++ R PVVVL D +LG   E +R P+ + 
Sbjct: 123 GGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPE-EA 181

Query: 218 VEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVH 277
           VE                    H                ++  S   +    + +   + 
Sbjct: 182 VE--------------------HRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQ 221

Query: 278 DKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLF 337
           +K  R     IE+N     +YEEY  DDAEI++V++G+S+R +  AV  AR EGI VGL 
Sbjct: 222 EKYAR-----IEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLL 273

Query: 338 VPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTV 397
            P T+ PFP +R+REL       +  EM+ GQM  ++ R  +    ++ VN++GG  + +
Sbjct: 274 RPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDI-RMASGCRDVELVNRMGGNLIEL 332

Query: 398 EEILREIRGVA 408
            ++L +IR VA
Sbjct: 333 RDVLEKIREVA 343


>gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, subunit alpha; PorA
           [Halobacterium sp. NRC-1]
           Length = 582
           
 Score =  200 bits (504), Expect = 2e-50
 Identities = 140/381 (36%), Positives = 199/381 (51%), Gaps = 22/381 (5%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           GDEA+  GAI AGCRFYAGYPITP++++ E +   + + GG+ +Q EDE+A+I   +GA+
Sbjct: 204 GDEAIGMGAIAAGCRFYAGYPITPATDVMEYLTGRIEQFGGHVVQAEDELAAINLALGAA 263

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
             G + MTATSGPG  LM E  G    +ETPLV+ +V RSGPSTG  TK  QGD      
Sbjct: 264 RAGARSMTATSGPGIDLMSETFGLVATSETPLVIANVMRSGPSTGMPTKQEQGDLNMMLK 323

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIP---DP 215
           G HG+ P   ++P SV + F +T+ AFN+AE+ + PV V  D  +  T E+   P   D 
Sbjct: 324 GGHGEIPRFVVAPTSVAECFHKTVEAFNLAEKYQLPVYVTADLSMAVT-ERTYPPEEFDM 382

Query: 216 DEVEIVYRKLP--------QNEEEARLPFGDPHGDGVPPMPLFGHGYFTHV-TGSTHKEN 266
           D VEI   KL         QN+ E   P  D   DG+ P  + G     H+ TG  H E 
Sbjct: 383 DAVEIERGKLVDEDEISAWQNDTEQFRPHADT-ADGISPRAVPGTEGGVHMSTGLEHDEL 441

Query: 267 GLRDVYTQEVHDKLVRRIHRKIEQNREVYE-KYEEYYTDDAEILVVSWGVSARPSLGAVL 325
           G R   T    D++ +R +RK++  RE  +  Y E+   DA+ LVVSWG S   ++   L
Sbjct: 442 GRRTEDTDVRVDQVDKR-YRKVDTAREREQFDYREFGDSDADNLVVSWG-SNEGTIVEAL 499

Query: 326 KARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVL-- 383
           +         + V    + +P   + +  +    ++V E N      +V   +  DVL  
Sbjct: 500 EYLDGDDDPDIRVVSVPYIYPRPDLTDEVEAADDVVVVEANATGQFADV---IEHDVLER 556

Query: 384 LKGVNKIGGVPLTVEEILREI 404
           +  +N   GV    +E+  EI
Sbjct: 557 VTRINNYTGVDFKADELAAEI 577


>pir||F70864 probable oxidoreductase alpha subunit - Mycobacterium tuberculosis
           (strain H37RV) >gi|2791495|emb|CAA16032.1| (AL021246)
           hypothetical protein Rv2455c [Mycobacterium
           tuberculosis]
           Length = 653
           
 Score =  190 bits (477), Expect = 3e-47
 Identities = 131/381 (34%), Positives = 193/381 (50%), Gaps = 13/381 (3%)

Query: 32  PGNYFMM-GDEAVAYGAIFAGCR-----FYAGYPITPSSEIAETMARELPKVGGYYLQME 85
           PG Y  + G+ A+AYG + AG           YPITP+S+I   +++          Q E
Sbjct: 248 PGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYPITPASDILHELSKH-KNFNVVTFQAE 306

Query: 86  DEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQA 145
           DEI  I A +GA++ G   +T+TSGPG SL  E LG  VMTE PL+++DVQR GPSTG  
Sbjct: 307 DEIGGICAALGAAYGGALGVTSTSGPGISLKSEALGLGVMTELPLLVIDVQRGGPSTGLP 366

Query: 146 TKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGH 205
           TK  Q D  QA +G +G+ P+  ++P S  D F   + A  +A    TPV++L DG + +
Sbjct: 367 TKTEQADLLQALYGRNGESPVAVLAPRSPADCFETALEAVRIAVSYHTPVILLSDGAIAN 426

Query: 206 TREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKE 265
             E  RIPD + +  +     +  E  + P+            + G     H  G     
Sbjct: 427 GSEPWRIPDVNALPPIKHTFAKPGEPFQ-PYARDRETLARQFAIPGTPGLEHRIGGLEAA 485

Query: 266 NGLRDV-YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAV 324
           NG  D+ Y    HD +VR    KI+    V +   +  T DAE+L++ WG S  P   A 
Sbjct: 486 NGSGDISYEPTNHDLMVRLRQAKID-GIHVPDLEVDDPTGDAELLLIGWGSSYGPIGEAC 544

Query: 325 LKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLL 384
            +AR+ G KV     + ++PFP   + E+ ++   ++ PE+NLGQ+   ++     DV  
Sbjct: 545 RRARRRGTKVAHAHLRYLNPFPA-NLGEVLRRYPKVVAPELNLGQLAQVLRGKYLVDV-- 601

Query: 385 KGVNKIGGVPLTVEEILREIR 405
           + V K+ GV    +EI R IR
Sbjct: 602 QSVTKVKGVSFLADEIGRFIR 622


>emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit [Streptomyces
           coelicolor]
           Length = 630
           
 Score =  186 bits (468), Expect = 3e-46
 Identities = 130/387 (33%), Positives = 200/387 (51%), Gaps = 24/387 (6%)

Query: 30  YKPGNYF-MMGDEAVAYGAIFAGCR-----FYAGYPITPSSEIAETMARELPKVGGYYLQ 83
           + PG Y  + G+ A+AYG I A  R     F   YPITP+S+I   +++     G    Q
Sbjct: 242 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKH-KNFGVRTFQ 300

Query: 84  MEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTG 143
            EDEIA I A +GA++ G   +T TSGPG +L  E +G AV  E PL++VD+QR GPSTG
Sbjct: 301 AEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPSTG 360

Query: 144 QATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGIL 203
             TK  Q D  QA +G +G+ P+  ++P +  D F   + A  +A   RTPV +L DG L
Sbjct: 361 LPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGYL 420

Query: 204 GHTREQIRIPDPDEVEIVYRKLPQ-------NEEEARLPF-GDPHGDGVPPMPLFGHGYF 255
            +  E  RIP+PDE+  +  +  Q       +  E   P+  DPH     P  + G    
Sbjct: 421 ANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPGL 479

Query: 256 THVTGSTHKENGLRDV-YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWG 314
            H  G   K++G  ++ Y    HD +VR    KI+         ++   D A  LV+ WG
Sbjct: 480 EHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKIDGITVPDLAVDD--PDGARTLVLGWG 537

Query: 315 VSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEV 374
            +  P   AV + RKE  ++     + ++PFP   +  + ++   ++VPEMNLGQ+   +
Sbjct: 538 STYGPITAAVRRIRKEVGQIAQAHLRHLNPFPA-NLGAVLERYDKVVVPEMNLGQLATLI 596

Query: 375 Q-RFVNDDVLLKGVNKIGGVPLTVEEI 400
           + +++ D    +  N++ G+P   E++
Sbjct: 597 RAKYLVD---AQSYNQVNGMPFKAEQL 620


>emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces coelicolor]
           Length = 645
           
 Score =  186 bits (468), Expect = 3e-46
 Identities = 130/387 (33%), Positives = 200/387 (51%), Gaps = 24/387 (6%)

Query: 30  YKPGNYF-MMGDEAVAYGAIFAGCR-----FYAGYPITPSSEIAETMARELPKVGGYYLQ 83
           + PG Y  + G+ A+AYG I A  R     F   YPITP+S+I   +++     G    Q
Sbjct: 257 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKH-KNFGVRTFQ 315

Query: 84  MEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTG 143
            EDEIA I A +GA++ G   +T TSGPG +L  E +G AV  E PL++VD+QR GPSTG
Sbjct: 316 AEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPSTG 375

Query: 144 QATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGIL 203
             TK  Q D  QA +G +G+ P+  ++P +  D F   + A  +A   RTPV +L DG L
Sbjct: 376 LPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGYL 435

Query: 204 GHTREQIRIPDPDEVEIVYRKLPQ-------NEEEARLPF-GDPHGDGVPPMPLFGHGYF 255
            +  E  RIP+PDE+  +  +  Q       +  E   P+  DPH     P  + G    
Sbjct: 436 ANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPGL 494

Query: 256 THVTGSTHKENGLRDV-YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWG 314
            H  G   K++G  ++ Y    HD +VR    KI+         ++   D A  LV+ WG
Sbjct: 495 EHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKIDGITVPDLAVDD--PDGARTLVLGWG 552

Query: 315 VSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEV 374
            +  P   AV + RKE  ++     + ++PFP   +  + ++   ++VPEMNLGQ+   +
Sbjct: 553 STYGPITAAVRRIRKEVGQIAQAHLRHLNPFPA-NLGAVLERYDKVVVPEMNLGQLATLI 611

Query: 375 Q-RFVNDDVLLKGVNKIGGVPLTVEEI 400
           + +++ D    +  N++ G+P   E++
Sbjct: 612 RAKYLVD---AQSYNQVNGMPFKAEQL 635


>pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha chain APE2126 -
           Aeropyrum pernix (strain K1) >gi|5105825|dbj|BAA81137.1|
           (AP000063) 644aa long hypothetical 2-oxoacid--ferredoxin
           oxidoreductase alpha chain [Aeropyrum pernix]
           Length = 644
           
 Score =  180 bits (452), Expect = 3e-44
 Identities = 123/359 (34%), Positives = 192/359 (53%), Gaps = 28/359 (7%)

Query: 31  KPGNYFMM-GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMAR-ELPKVGGY------YL 82
           K G Y +  G++ VA G +  G R+ A YPITP+S+ +  +   E  K+ G        L
Sbjct: 243 KSGEYVVASGNDVVAMGKVVGGVRYQAYYPITPASDESVLLEEFEGLKIDGESLGSIAIL 302

Query: 83  QMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPST 142
           Q EDEIA++++++GA+ TG +  TATSGPGFSLM E LG+A   + P+V+   QR GPST
Sbjct: 303 QTEDEIAAVSSVIGAALTGARASTATSGPGFSLMVEALGWAGKNDVPMVITYYQRGGPST 362

Query: 143 GQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGI 202
           G  T+G+Q D   + + +HG+ P + +S     +AF++ I A+N+AER + PV+ L D  
Sbjct: 363 GLPTRGSQSDLLFSLFASHGEFPRIILSSGDHLEAFYDAIEAYNLAERFQMPVIHLLDKF 422

Query: 203 LGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGD----PHGDGVPPMPLFGHGYFTHV 258
           L +    +  PD   +     K+ + +   + P G     P    +   P+ G G  T  
Sbjct: 423 LANMVASVPFPDWKAI-----KIDRGKTLFKAPTGPFKRFPRDQPLADRPVLGSGAITWY 477

Query: 259 TGSTHKENGLRDVYTQEVHDKLV--RRIHRKIE-QNREVYEKYE-EYYTD-DAEILVVSW 313
           TG  + E G  D   ++  ++LV   R  +K+E  +RE+ E +  +YY D DAE+L+V W
Sbjct: 478 TGDENDEYGHID---EDPVNRLVMYERRWKKMEIADREIPEDFRVKYYGDEDAEVLLVGW 534

Query: 314 GVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKV---RAILVPEMNLGQ 369
           G    P+L A+ + R+ G+       + + P P  R+ E+  +    R I V    LGQ
Sbjct: 535 GSVKIPALEAIERLREMGVNAAYLHLRMLSPLPKRRVSEVLSRFDADRVIAVEANYLGQ 593


>pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validated] -
           Halobacterium salinarum >gi|43498|emb|CAA45825.1|
           (X64521) pyruvate synthase [Halobacterium halobium]
           Length = 628
           
 Score =  176 bits (442), Expect = 4e-43
 Identities = 129/398 (32%), Positives = 191/398 (47%), Gaps = 45/398 (11%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96
           M G  A+AYGAI AGCRF +GYP+TP ++    M + LP +GG   Q+EDEIA+ A  VG
Sbjct: 223 MSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVEDEIAAAAMAVG 282

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156
           AS  G K M+ +SG GF+LM E LG A MTETPLVL++ QR+GPSTG  TK  Q D    
Sbjct: 283 ASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMPTKPEQADLEHV 342

Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFD---------------- 200
            + + GD   VA  P   ++ + +T  AF +A   + PV++L+D                
Sbjct: 343 LYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSGEYRNVDASFFD 402

Query: 201 ----GILGHTREQIRIPD-PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYF 255
                 LG T  + +IPD P +    Y +   + E           DGV P  + G    
Sbjct: 403 REPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVE-----------DGVSPRTIPGQSGG 451

Query: 256 THV-TGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE------YYTDDAEI 308
            ++ +G+ H  NG    +  E  D  V ++ R++++   + +  +E      Y  +DA+I
Sbjct: 452 RYLASGNEHWPNG----HISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADI 507

Query: 309 LVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLG 368
            +++WG        AV +   +G  V       + PFP    R     V   +V EM+  
Sbjct: 508 GLIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSST 567

Query: 369 QMILE-VQRFVND-DVLLKGVNKIGGVPLTVEEILREI 404
           +     +Q+ V D    L  + K  G P    EI+  +
Sbjct: 568 KQFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 605


>gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin oxidoreductase
           (alpha); KorA [Halobacterium sp. NRC-1]
           Length = 640
           
 Score =  176 bits (442), Expect = 4e-43
 Identities = 129/398 (32%), Positives = 191/398 (47%), Gaps = 45/398 (11%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96
           M G  A+AYGAI AGCRF +GYP+TP ++    M + LP +GG   Q+EDEIA+ A  VG
Sbjct: 235 MSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVEDEIAAAAMAVG 294

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156
           AS  G K M+ +SG GF+LM E LG A MTETPLVL++ QR+GPSTG  TK  Q D    
Sbjct: 295 ASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMPTKPEQADLEHV 354

Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFD---------------- 200
            + + GD   VA  P   ++ + +T  AF +A   + PV++L+D                
Sbjct: 355 LYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSGEYRNVDASFFD 414

Query: 201 ----GILGHTREQIRIPD-PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYF 255
                 LG T  + +IPD P +    Y +   + E           DGV P  + G    
Sbjct: 415 REPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVE-----------DGVSPRTIPGQSGG 463

Query: 256 THV-TGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE------YYTDDAEI 308
            ++ +G+ H  NG    +  E  D  V ++ R++++   + +  +E      Y  +DA+I
Sbjct: 464 RYLASGNEHWPNG----HISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADI 519

Query: 309 LVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLG 368
            +++WG        AV +   +G  V       + PFP    R     V   +V EM+  
Sbjct: 520 GLIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSST 579

Query: 369 QMILE-VQRFVND-DVLLKGVNKIGGVPLTVEEILREI 404
           +     +Q+ V D    L  + K  G P    EI+  +
Sbjct: 580 KQFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 617


>emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidoreductase, alpha
           chain [Thermoplasma acidophilum]
           Length = 629
           
 Score =  176 bits (442), Expect = 4e-43
 Identities = 118/397 (29%), Positives = 193/397 (47%), Gaps = 18/397 (4%)

Query: 26  LRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETM------------ARE 73
           L  L  P    + G++A A G +  G RF   YPITP+S+ + T+            A  
Sbjct: 222 LPALPTPRKLLLTGNDASALGKLLGGLRFQTYYPITPASDESTTIEEHQNIKWLDKEAAN 281

Query: 74  LPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLV 133
           L K G   +Q EDE++++   +G + TG++  TATSGPGFSLM E L +A M E PLV+ 
Sbjct: 282 LKKGGVVIVQTEDELSAVNMAIGGALTGVRSATATSGPGFSLMAEGLSFAGMDEVPLVVT 341

Query: 134 DVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRT 193
             +R GPSTG  T+  Q D   A    HG++P +  S  +V++  ++  +A N A + + 
Sbjct: 342 FYERGGPSTGLPTRNGQSDLLFALNAGHGEYPRIVFSSGTVDECIYDAAKALNYAAKYQM 401

Query: 194 PVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHG 253
           PV+ L D  L +T + I   D D ++I   KL +  ++ +  +     +GV P    G  
Sbjct: 402 PVIHLIDKNLANTLDLISKVDLDRIKIETVKLAKEGDDVK-RYDLNTDNGVSPYTTMGRN 460

Query: 254 YFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE-QNRE--VYEKYEEYYTDDAEILV 310
            F  +TG  H E G       ++ D+++ +  +K+E  +RE  + EK       +A+I  
Sbjct: 461 IF-WMTGDEHDELG-HVTEDSDIRDRMMEKRFKKLETADREIPIDEKAVLIGEKEADITF 518

Query: 311 VSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQM 370
           V+WG    P L  +   ++EGI   L   K   PFP E ++ +      ++  E N    
Sbjct: 519 VTWGSQKGPILDVIEDLKEEGISANLLYLKMFSPFPTEFVKNVLSSANLVIDVESNYTAQ 578

Query: 371 ILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGV 407
             ++ +      +   + K  G  +T +EIL+  + +
Sbjct: 579 AAQMIKLYTGIDIKNKILKYNGRHMTEDEILKSAKEI 615


>emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidoreductase, alpha
           subunit [Thermoplasma acidophilum]
           Length = 588
           
 Score =  168 bits (420), Expect = 1e-40
 Identities = 116/371 (31%), Positives = 184/371 (49%), Gaps = 16/371 (4%)

Query: 26  LRKLYKPGN--YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQ 83
           L K +K G   Y + G  AVA GA+  G + Y  YP+TP+S     +A+   K G +   
Sbjct: 195 LGKKFKFGKKKYMISGGMAVALGAVAGGLKMYVAYPMTPASSALHFLAQHAKKYGVFVKI 254

Query: 84  MEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTG 143
            EDEI++I  ++GA++ G++ MT +SG GF+LM E +G + MTE PLV+ + QR GPSTG
Sbjct: 255 PEDEISAINTVIGANYAGVRAMTGSSGGGFALMTEAVGLSGMTEVPLVIYEAQRPGPSTG 314

Query: 144 QATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGIL 203
             TK  QGD  Q    + GD P +  +P  +E+AF+ T  A N+AE+ +TPV V+ D  L
Sbjct: 315 LPTKTEQGDLNQVLGASQGDFPRIVFAPGDIEEAFYLTREAMNIAEKYQTPVFVMSDLYL 374

Query: 204 GHTREQIRIPDPD-EVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGH-GYFTHVTGS 261
               + I   D +  ++   R     ++  R    +    G+ P  + G  G   +    
Sbjct: 375 AEHYDTIDSFDLNFNIDHGLRAKDNEQDYKRYLITE---TGISPRAIPGQPGNMHNEDSD 431

Query: 262 THKENGLRDVYTQEVHD-----KLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVS 316
            H E G  DV +  V +     K++++  RK++   E  +    Y   DAE +++ WG +
Sbjct: 432 EHNEYG--DVVSDAVTNPQDRIKMMQKRMRKLDTYIEEMKPTPTYRIQDAEYVIIQWGST 489

Query: 317 ARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQM--ILEV 374
                 A+   R +GIK+G    K V P   +    L  + + + V     GQ+   +  
Sbjct: 490 KGAVEEAIDILRAKGIKIGAIEVKNVFPLNPDIGTLLKNRKKILAVENNYSGQLSKYIAA 549

Query: 375 QRFVNDDVLLK 385
           Q  V  +++ K
Sbjct: 550 QFLVKPELITK 560


>pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha chain APE1473
           - Aeropyrum pernix (strain K1)
           >gi|5105157|dbj|BAA80471.1| (AP000061) 616aa long
           hypothetical 2-oxoacid--ferredoxin oxidoreductase ,
           alpha chain [Aeropyrum pernix]
           Length = 616
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 127/393 (32%), Positives = 192/393 (48%), Gaps = 32/393 (8%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSE------------IAETMAREL--PKVGGYYLQM 84
           G++ VA G I  G      YPITPSS+            I   +A +L   K+    +QM
Sbjct: 218 GNDLVAMGKIVGGLGVITYYPITPSSDEALYVEKHSYISIDGPLAEKLGYDKIAVAIVQM 277

Query: 85  EDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQ 144
           EDE+ASI A++GA+  G +  T TSGPGFSLM E +  AV  E P+V+    R+GPSTG 
Sbjct: 278 EDELASINAVLGAAAAGARASTTTSGPGFSLMNEAVSLAVEAEIPVVVTLWMRAGPSTGM 337

Query: 145 ATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILG 204
            T+  Q D   + +  HGD P + ++     +AF++ I+AFN AE  +TPV+ L D  L 
Sbjct: 338 PTRTGQQDLLHSIFSGHGDAPKIVLASGDHVEAFYDAIKAFNWAEEFQTPVIHLLDKYLA 397

Query: 205 HT-----REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVT 259
            +     RE +   DP +V I   KL  N       + +   DG+ P    G      +T
Sbjct: 398 SSMVSLAREDL---DPSKVPITRGKLLDNPPADYRRY-EVVEDGISPRARLGSATMV-IT 452

Query: 260 GSTHKENG--LRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSA 317
           G  H E G    D   +E+      R  + IE+     EK   +   +A + +VS+G + 
Sbjct: 453 GLEHDEYGYATEDPVMREIMMFKRERKFKVIEERIPDEEKAVLHGDSEASVALVSFGSTK 512

Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN-LGQ--MILEV 374
           +P L A+   R EG++      + ++PFPG  + E+ + V  +++ E N LGQ  M+L  
Sbjct: 513 QPILEALEMLRDEGVRARFAQVRLLYPFPGRLVEEMLEGVEKVIMVEQNLLGQLAMLLRA 572

Query: 375 QRFVNDDVLLKGVNKIGGVPLTVEEILREIRGV 407
              +  D     + KI G PL   E+   ++ +
Sbjct: 573 HTSIKPD---SSIVKINGRPLYSFEVAGAVKRI 602


>gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain [Sulfolobus
           solfataricus]
           Length = 632
           
 Score =  162 bits (407), Expect = 5e-39
 Identities = 120/385 (31%), Positives = 182/385 (47%), Gaps = 17/385 (4%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSS------EIAETMARELPKVGG------YYLQMED 86
           G+ A A G I+ G RF + YPITP+S      E  +T+    PK G         +Q ED
Sbjct: 235 GNTAAAIGKIYGGLRFQSYYPITPASDESVFIEAHQTVFTVDPKTGEKRKSTIVVVQAED 294

Query: 87  EIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQAT 146
           E+A+I    GA+ TG++  TATSGPGFSLM E +G+A M E P+V+    R GPSTGQ T
Sbjct: 295 ELAAINMASGAALTGVRAATATSGPGFSLMVEGMGWAGMNEVPVVITYYIRGGPSTGQPT 354

Query: 147 KGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHT 206
           + +Q D   A    HG+ P + I+     +AF +   A N+A++ +TPV+ L D  L ++
Sbjct: 355 RTSQADLMFALNAGHGEFPRIVIASGDHVEAFHDGTWALNLAQKYQTPVIHLVDKALANS 414

Query: 207 REQI--RIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHK 264
              I  +    + + I   K+  N     L   +   DG+ P    G     H TG  H 
Sbjct: 415 YSIIPKKTLGMENIRIEKGKIVINTNTPELKRFEITEDGISPFAPLGTAR-VHYTGDEHD 473

Query: 265 ENGLRDVYTQEVHDKLVRRIHRKIEQNREVYE--KYEEYYTDDAEILVVSWGVSARPSLG 322
           E G     ++       +RI + +  ++E+ E  +   Y   D+++ +++WG      L 
Sbjct: 474 EYGFIAEASENREKMYEKRIKKLMTADKEIPEESRVNVYGNTDSKVAIITWGSPKGAILD 533

Query: 323 AVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDV 382
           A+ +   EGIK  L   +   PFP   MR+L      I+  E N      EV +      
Sbjct: 534 AMEELENEGIKPMLIQIRMFSPFPKNLMRKLLNGKEFIIDVESNYFGQAGEVLKLNTGIE 593

Query: 383 LLKGVNKIGGVPLTVEEILREIRGV 407
               + K  G P+  +E+   I+ V
Sbjct: 594 PTHYILKWNGRPMMRDEVKEGIKAV 618


>pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit - Thermotoga
           maritima (strain MSB8)
           >gi|4981713|gb|AAD36240.1|AE001773_9 (AE001773)
           2-oxoacid ferredoxin oxidoreductase, alpha subunit
           [Thermotoga maritima]
           Length = 558
           
 Score =  153 bits (382), Expect = 4e-36
 Identities = 115/372 (30%), Positives = 184/372 (48%), Gaps = 14/372 (3%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G EAV  GAI  GC F + YP++PS+ +   +A+     G    Q EDEIA++  ++GA 
Sbjct: 197 GAEAVGLGAIAGGCNFVSSYPMSPSTSVLVFLAQHKNDFGIVVEQAEDEIAAMNMIIGAW 256

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
           + G + +  TSG GF+LM+E L  A M E+P V+   QR GP+TG  T+  QGD   A +
Sbjct: 257 YAGARGLVTTSGGGFALMEEALSLAGMIESPAVIHLAQRPGPATGLPTRTEQGDLNLALY 316

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218
             HGD P V  +P +VE+AF+ T +AFNVA++ + PV VL D  L  +   +   D +E+
Sbjct: 317 AGHGDFPRVIYAPGNVEEAFYLTQKAFNVADKYQVPVFVLTDQYLVDSYYNLPGFDLNEL 376

Query: 219 EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGY-FTHVTGSTHKENG-LRDVYTQEV 276
           ++    +    +  R    +   DG+ P  + G+G     V    H E G + + +   V
Sbjct: 377 KVEKHFIKTTRDYIRYAITE---DGISPRGIPGYGEGLVRVDSDEHDEFGHITEDFNTRV 433

Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIK-VG 335
             ++V +  RK E  ++   K +    ++  +L+V+WG +  P     +K   EG+  V 
Sbjct: 434 --RMVNKRLRKGETLKKEIVKPKLIGDENYRVLLVAWGSTLEP-----IKEAIEGLDGVA 486

Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395
           L     V P   E +    +K   ++  E N       + R V    +   + K  G+  
Sbjct: 487 LLHFSQVWPI-DESVATYFEKAEKVVAVEGNATGQFANLIRQVTGFHIKDRILKYNGLQF 545

Query: 396 TVEEILREIRGV 407
           +VEE+  +I  V
Sbjct: 546 SVEELKEKIAEV 557


>pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621610|gb|AAB85042.1| (AE000836)
           2-oxoacid:ferredoxin oxidoreductase, alpha subunit
           [Methanobacterium thermoautotrophicum]
           Length = 512
           
 Score =  143 bits (357), Expect = 4e-33
 Identities = 113/365 (30%), Positives = 173/365 (46%), Gaps = 17/365 (4%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G EAV  G I  GCRF + YP+TPS+ +   ++    +    + Q EDEIA+I   +GAS
Sbjct: 153 GTEAVGIGCIAGGCRFMSSYPMTPSTPLQVFISENAAEFDMVFEQAEDEIAAINMCLGAS 212

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
           + G + + ATSG GF+LM+E +G A M ETP+V+   QR GP+ G  T+ AQ D   A +
Sbjct: 213 YAGARSLVATSGSGFALMEEAVGLAGMIETPVVIYIGQRPGPAVGLPTRTAQEDLNLALY 272

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218
              G+ P   ++P  +EDA      AFN+A+R + PV +L D  L      +  P   E 
Sbjct: 273 AGPGEFPRAILAPGKLEDAPEIAAHAFNLADRYQIPVFLLSDQYLADLYYDLPSPQIGE- 331

Query: 219 EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFT-HVTGSTHKENGLRDVYTQEVH 277
           E  Y      E   R  F     DG+ P  + G+G  T  V    H E GL      +V 
Sbjct: 332 EPSYHITRTWEGYRRFEF---TADGISPRGIPGYGSGTVRVDSDEHDEEGL-ITEDLDVR 387

Query: 278 DKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLF 337
            ++V + + ++E  ++   K E Y   D    ++ WG +      A+      G  V + 
Sbjct: 388 RRMVEKRNLRLEMLKDDTLKPEVY--GDNSSALICWGSTYWLVREAI---ESSGADVSMV 442

Query: 338 VPKTVHPFPGERMRELGKKVRAILVPEMNLGQM--ILEVQRFVNDDVLLKGVNKIGGVPL 395
               V+P P + +  L    R  +V     GQ   +L+++ F  D+       +  G+P 
Sbjct: 443 HFSQVYPLPHDTLELLESFDRTAVVENNYRGQFADLLKLEGFEADE----RFRRYDGMPF 498

Query: 396 TVEEI 400
           +VE +
Sbjct: 499 SVEGV 503


>pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           [validated] - Sulfolobus sp. (strain 7)
           >gi|1565183|dbj|BAA10898.1| (D64024)
           2-oxoacid:ferredoxin oxidoreductase subunit alpha
           [Sulfolobus sp. 7]
           Length = 632
           
 Score =  141 bits (351), Expect = 2e-32
 Identities = 121/403 (30%), Positives = 197/403 (48%), Gaps = 38/403 (9%)

Query: 19  EPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSS------EIAETMAR 72
           +P  KE  R       +++ G+ AVA G I+ G RF + YPITP+S      E  + +  
Sbjct: 221 KPSSKERRR-------FWLDGNTAVAIGKIYGGVRFQSYYPITPASDESVYIEAHQDVLM 273

Query: 73  ELPKVGG------YYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMT 126
           E P  G         +Q EDE+A+I   +GA+ TG++  TATSGPGFSLM E LG+A M 
Sbjct: 274 EDPITGDKKKGTIVVVQAEDELAAINMAIGAALTGVRAATATSGPGFSLMVEGLGWAGMN 333

Query: 127 ETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFN 186
           E P+V+    R GPSTG  T+ AQ D     +  HG+ P + ++     +AF + I A N
Sbjct: 334 EVPVVITYYIRGGPSTGLPTRTAQSDLIFPIFAGHGEFPKIVLASGDHAEAFKDAIWALN 393

Query: 187 VAERLRTPVVVLFDGILGHTREQIRIP--DPDEVEIVYRKLPQNEEEA--RLPFGDPHGD 242
           +AE+ +TPV+ L +  L ++   I     + D+++    K+ ++ + +  R  F +   D
Sbjct: 394 LAEKYQTPVIHLVEKTLANSYSTIPYEELELDKLKAERGKIVESGDISYKRFKFTE---D 450

Query: 243 GVPPMPLFGHGYFTHVTGSTHKENG--LRDVYTQE-VHDKLVRRIHRKIEQNREVYEKYE 299
           G+ P    G     + TG  H E G    DV  +  +++K ++++  ++       E   
Sbjct: 451 GISPRAFLGKATM-YYTGDEHNEEGHISEDVVNRTMMYEKRMKKL--EVADKEIPEESRV 507

Query: 300 EYYTD-DAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVR 358
           + Y D ++  L+++WG S    L  +L+  +      L   +   PFP   + +L +   
Sbjct: 508 KIYGDLNSRNLIITWG-SPTGVLRDILE--ESNFDFTLLQIRMFSPFPKNLVSKLMEGRD 564

Query: 359 AILVPEMN-LGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEI 400
            I+  E N L Q  L V+ +   DV    + K  G P   +E+
Sbjct: 565 KIITVEGNYLAQTSLLVKMYTGKDV-TNSILKWNGRPFLRDEL 606


>emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma and alpha subunit in
           fusion) [Thermus thermophilus]
           Length = 617
           
 Score =  138 bits (343), Expect = 2e-31
 Identities = 127/412 (30%), Positives = 188/412 (44%), Gaps = 27/412 (6%)

Query: 9   KVVGMIIRGDEPEQKELLRKLYK-PGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIA 67
           KV   + R + P     L  L   PG  ++ G +A A G +  G RF   YPI+P+++ +
Sbjct: 205 KVAEAVYREEAPRLPFRLEVLGPAPGRIYLTGAQAAALGKLAGGLRFQTYYPISPATDES 264

Query: 68  ETMARE--LPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVM 125
             +     LP      +Q EDEIA++   VGA+  G K  TATSGPGFSLM E LG+A M
Sbjct: 265 VFLEAHTHLPGADVAVVQTEDEIAAVNMAVGAALAGAKAATATSGPGFSLMAEGLGFAGM 324

Query: 126 TETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAF 185
            E PLV+   QR        T+  QGD   A  G HG++P + ++   + DAF +  +A 
Sbjct: 325 IEAPLVVTLYQRGRAQHRLPTRTEQGDLMFAIRGGHGEYPRLVLASGDILDAFLDAQKAL 384

Query: 186 NVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGD-----PH 240
             A R +T VV L D  L    + +    P E   V     +     R  FG      P 
Sbjct: 385 AWAWRYQTVVVHLLDKFLASLAQSL----PKEALKVLSLDGEKRLSPREGFGPYQRYAPG 440

Query: 241 GDGVPP-MPLFGHGYFTHVTGSTHKENG--LRDVYTQEVHDKLVRRIHRKIEQNREVYEK 297
            DG+ P +P+   G F  +T   H   G    DV  +E+  ++ +R+ +     +E+   
Sbjct: 441 EDGLSPFIPIGTPGGFYWMTSDEHDPLGHITEDVELREL--QMEKRMEKLELARKEI--P 496

Query: 298 YEEYYT--DDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGK 355
            E+ YT   D E+LV+ WG       G +L+A      VG    + + PFP  R+  L +
Sbjct: 497 LEDQYTLFRDGEVLVLGWGTVK----GTLLEALDHLEGVGYLHLRLLWPFP--RIAPLLE 550

Query: 356 KVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGV 407
               + V     GQ+   VQ+     V  + V   G  P  +EE +  ++ V
Sbjct: 551 GKTLVTVEHNYSGQLADLVQQETLKRVHHRVVKYNGRAPSPLEEAVEALKVV 602


>gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA)
           [Archaeoglobus fulgidus] >gi|7433693|pir||E69343
           2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha
           chain orA - Archaeoglobus fulgidus
           >gi|2649863|gb|AAB90491.1| (AE001053) 2-oxoacid
           ferredoxin oxidoreductase, subunit alpha (orA)
           [Archaeoglobus fulgidus]
           Length = 532
           
 Score =  123 bits (306), Expect = 3e-27
 Identities = 97/314 (30%), Positives = 151/314 (47%), Gaps = 29/314 (9%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98
           G  A+A G + AG +FY  YP+TP+S I   +A +   V    LQ E+EIA+I   +G++
Sbjct: 184 GARAIAEGMLAAGLKFYYAYPMTPASPILHILAADSRCVA---LQPENEIAAIMMAIGSA 240

Query: 99  WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158
           + G +    TSG GF+LM E++  A M E P++++  QRSGPSTG AT  AQ D + A  
Sbjct: 241 FGGERAAVGTSGGGFALMSESISLAGMAEVPVLIILAQRSGPSTGMATYTAQQDLYFALN 300

Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD--PD 216
             HG+ P++  SP+++ED++       N+A + +TP ++L +  +  +    ++      
Sbjct: 301 PAHGEFPLIVASPITIEDSYRLAGELLNLAWQFQTPAILLTEKHITESLATAKLEGVVKR 360

Query: 217 EVEIVYRKLPQNEEEARLPFG-DPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275
           EVEI   K    +  A    G  P+    PP              + H E G       E
Sbjct: 361 EVEIFREKGELFKRYAITESGISPY--AAPPA-------IFKANSNEHDEYGFA-TDDAE 410

Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEY-YTDDAEILVVSWGVSARPSLGAVLKARKE-GIK 333
              K+  +  RK E+ R V      Y    + +  +V+WG     + GAV +  +E G  
Sbjct: 411 TATKMYAKRMRKEEEIRRVVANLNPYVVVKNGKDWIVTWG----SNFGAVKEVAEELGFS 466

Query: 334 VG-------LFVPK 340
           V        LF+PK
Sbjct: 467 VAAIRYMRPLFLPK 480


>pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain PAB1472 [similarity] - Pyrococcus abyssi
           (strain Orsay) >gi|5458784|emb|CAB50271.1| (AJ248287)
           KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-)
           (VOR) [Pyrococcus abyssi]
           Length = 395
           
 Score =  113 bits (280), Expect = 4e-24
 Identities = 98/349 (28%), Positives = 155/349 (44%), Gaps = 39/349 (11%)

Query: 30  YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87
           YKP    + G+ A AY  + A  +  A YPITP + I E +A  +   +    Y+ +E E
Sbjct: 4   YKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 63

Query: 88  IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147
            +++AA +GAS TG +V TATS  G +LM E L +A     P+V+VDV R+  +   +  
Sbjct: 64  HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRA-MAPPWSVW 122

Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-ILGHT 206
             Q D    R     D   +     + ++ +   + AF VAE +  P +V+    IL HT
Sbjct: 123 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHT 177

Query: 207 REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTH-------VT 259
            E            +   +PQ   +  LP         P  PL+    F +        T
Sbjct: 178 YE------------IVNMIPQELVDEFLP---------PRKPLYSLADFENPIAVGALAT 216

Query: 260 GSTHKENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSA 317
            + + E   +     E   K+++ + R+  +   R+  E  E+ Y DDA+ + +  G   
Sbjct: 217 PADYYEFRYKLARAHEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLM 276

Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366
                AV   RK+G KVG    +   PFP E + E+ + V+ I V + N
Sbjct: 277 GTVKEAVELLRKQGYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325


>sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280154|pir||T45085
           2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain vorA - Pyrococcus furiosus
           >gi|1197360|emb|CAA59502.1| (X85250) 2-ketovalerate
           ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus]
           Length = 394
           
 Score =  109 bits (269), Expect = 7e-23
 Identities = 96/349 (27%), Positives = 153/349 (43%), Gaps = 39/349 (11%)

Query: 30  YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87
           YKP    + G+ A AY A+ A  +  A YPITP + I E +A  +   +    Y+ +E E
Sbjct: 3   YKPIRKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 62

Query: 88  IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147
            +++AA +GAS TG +  TATS  G +LM E L +A     P+V+VDV R+  +   +  
Sbjct: 63  HSAMAACIGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRA-MAPPWSVW 121

Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-ILGHT 206
             Q D    R     D   +     + ++ +   + A+ VAE +  P +V+    IL HT
Sbjct: 122 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAYKVAETVNVPAMVVESAFILSHT 176

Query: 207 REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTH-------VT 259
            +            V   +PQ   +  LP         P  PL+    F          T
Sbjct: 177 YD------------VVEMIPQELVDEFLP---------PRKPLYSLANFDEPIAVGALAT 215

Query: 260 GSTHKENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSA 317
            + + E   +     E   K+++ + ++  +   R+  +  E  Y DDA+ + +  G   
Sbjct: 216 PNDYYEFRYKLAKAHEEAKKVIKEVGKEFGERFGRDYSQMIETGYIDDADFVFMGMGSLM 275

Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366
                AV   RKEG KVG    +   PFP E + E+ + V+ I V + N
Sbjct: 276 GTVKEAVDLLRKEGYKVGYAKVRWFRPFPKEELVEIAESVKGIAVLDRN 324


>pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 - Pyrococcus
           abyssi (strain Orsay) >gi|5458781|emb|CAB50268.1|
           (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1)
           (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus
           abyssi]
           Length = 395
           
 Score =  108 bits (266), Expect = 2e-22
 Identities = 102/337 (30%), Positives = 155/337 (45%), Gaps = 26/337 (7%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           M  +EA A+ A  A  +  A +PITPS+ + E ++  +   ++   ++++E E ++I+A+
Sbjct: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
           VGAS  G++  TAT+  G +LM E L  A     P+V+    R+  +        Q    
Sbjct: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211
           Q   G       +     + ++A    + A+ VAE  R+  P +V FD  IL HT E + 
Sbjct: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180

Query: 212 IPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270
           IPD    E+V   L + E + A L    P   G    P   H            EN  + 
Sbjct: 181 IPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFP--AHYMEARYLVWEAMENARKV 235

Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330
           +   E   +  ++  RK       Y+K EEY TDDAEI+ V+ G  A      V K R+E
Sbjct: 236 I--DEAFAEFEKKFGRK-------YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREE 286

Query: 331 GIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367
           G KVG        PFP E +REL KK + +   E ++
Sbjct: 287 GYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDI 323


>pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit - Pyrococcus
           horikoshii >gi|3257092|dbj|BAA29775.1| (AP000003) 398aa
           long hypothetical ferredoxin oxidoreductase alpha-2
           subunit [Pyrococcus horikoshii]
           Length = 398
           
 Score =  107 bits (265), Expect = 2e-22
 Identities = 103/337 (30%), Positives = 153/337 (44%), Gaps = 26/337 (7%)

Query: 30  YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87
           + P    M  +EA A+ A  A  +  A +PITPS+ + E ++  +   ++   ++++E E
Sbjct: 3   FMPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESE 62

Query: 88  IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147
            ++I+A+VGAS  G++  TAT+  G +LM E L  A     P+V+    RS  +      
Sbjct: 63  HSAISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWN 122

Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILG 204
             Q    Q   G       +     + ++A    + A+ VAE  R+  P +V FD  IL 
Sbjct: 123 DWQDSISQRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILT 176

Query: 205 HTREQIRIPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTH 263
           HT E + IPD    E+V   L + E + A L    P   G    P         V  +  
Sbjct: 177 HTVEPVEIPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAME 233

Query: 264 KENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGA 323
           K   + D    E   +  +R  RK       Y+K EEY TDDAEI+ V+ G  A      
Sbjct: 234 KARKVID----EAFAEFEKRFGRK-------YQKIEEYKTDDAEIIFVTMGSLAGTLKDW 282

Query: 324 VLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360
           V K R+EG KVG        PFP E +R L KK + +
Sbjct: 283 VDKKREEGYKVGAAKMTVYRPFPVEEIRALAKKAKVL 319


>sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT)
           Length = 395
           
 Score =  106 bits (263), Expect = 4e-22
 Identities = 102/330 (30%), Positives = 151/330 (44%), Gaps = 26/330 (7%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           M  +EA A+ A  A  +  A +PITPS+ + E ++  +   ++   ++++E E ++I+A+
Sbjct: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAV 66

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
           VGAS  G++  TAT+  G +LM E L  A     P+V+    RS  +        Q    
Sbjct: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWNDWQDSIS 126

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211
           Q   G       +     + ++A    + A+ VAE  R+  P +V FD  IL HT E + 
Sbjct: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180

Query: 212 IPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270
           IPD    E+V   L + E + A L    P   G    P         V  +  K   + D
Sbjct: 181 IPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVID 237

Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330
               E   +  +R  RK       Y+K EEY TDDAEI+ V+ G  A      V K R+E
Sbjct: 238 ----EAFAEFEKRFGRK-------YQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREE 286

Query: 331 GIKVGLFVPKTVHPFPGERMRELGKKVRAI 360
           G KVG        PFP E +R L KK + +
Sbjct: 287 GYKVGAAKMTVYRPFPVEEIRALAKKAKVL 316


>pir||A71114 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3257088|dbj|BAA29771.1| (AP000003) 397aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 397
           
 Score =  106 bits (262), Expect = 5e-22
 Identities = 97/347 (27%), Positives = 158/347 (44%), Gaps = 29/347 (8%)

Query: 27  RKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQM 84
           R  Y P    + G+ A AY A+ A  +  A YPITP + I E +A  +   +    Y+ +
Sbjct: 3   RMEYNPIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV 62

Query: 85  EDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQ 144
           E E +++AA +GAS TG +V TATS  G +LM E L +A  +  P+V+V+V R+  +   
Sbjct: 63  ESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRA-MAPPW 121

Query: 145 ATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-IL 203
           +    Q D    R     D   +     + ++ +   + A+ VAE +  P +++    IL
Sbjct: 122 SVWDDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFIL 176

Query: 204 GHTREQIR-IPDPDEVEIVYRKLPQNEEEARL-PFGDPHGDGVPPMPLFGHGYFTHVTGS 261
            HT E +  IP     E+V   LP  +    L  F +P   G    P   +  F +    
Sbjct: 177 SHTYEVVNMIPQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPA-DYYEFRYKIAK 231

Query: 262 THKENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSARP 319
            H+E             K+++ + ++  +   R+  +  E  Y +DA+ + +  G     
Sbjct: 232 AHEE-----------AKKVIKSVGKEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGT 280

Query: 320 SLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366
              AV   RKEG KVG    +   PFP E + E+ + V+ I V + N
Sbjct: 281 VKEAVDLLRKEGYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 327


>sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE ALPHA SUBUNIT)
           Length = 394
           
 Score =  106 bits (261), Expect = 6e-22
 Identities = 96/344 (27%), Positives = 157/344 (44%), Gaps = 29/344 (8%)

Query: 30  YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87
           Y P    + G+ A AY A+ A  +  A YPITP + I E +A  +   +    Y+ +E E
Sbjct: 3   YNPIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 62

Query: 88  IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147
            +++AA +GAS TG +V TATS  G +LM E L +A  +  P+V+V+V R+  +   +  
Sbjct: 63  HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRA-MAPPWSVW 121

Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-ILGHT 206
             Q D    R     D   +     + ++ +   + A+ VAE +  P +++    IL HT
Sbjct: 122 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHT 176

Query: 207 REQIR-IPDPDEVEIVYRKLPQNEEEARL-PFGDPHGDGVPPMPLFGHGYFTHVTGSTHK 264
            E +  IP     E+V   LP  +    L  F +P   G    P   +  F +     H+
Sbjct: 177 YEVVNMIPQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPA-DYYEFRYKIAKAHE 231

Query: 265 ENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSARPSLG 322
           E             K+++ + ++  +   R+  +  E  Y +DA+ + +  G        
Sbjct: 232 E-----------AKKVIKSVGKEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKE 280

Query: 323 AVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366
           AV   RKEG KVG    +   PFP E + E+ + V+ I V + N
Sbjct: 281 AVDLLRKEGYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 324


>dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase alpha subunit
           [Hydrogenobacter thermophilus]
           Length = 400
           
 Score =  106 bits (261), Expect = 6e-22
 Identities = 110/391 (28%), Positives = 170/391 (43%), Gaps = 54/391 (13%)

Query: 35  YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVG--GYYLQMEDEIASIA 92
           +FM G EAV      A       YPITP SE A  +  EL   G  G Y + E E   ++
Sbjct: 31  HFMTGSEAVKEAVKRASVDASVSYPITPQSEAAHLIG-ELWVEGYVGVYFRGESEFGVMS 89

Query: 93  AMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGD 152
            + G +  G + +T TSGPG     EN      T  P+ LV + R       A    Q D
Sbjct: 90  EIAGCALAGARTITTTSGPGTLRAMENFPMWAGTRIPVQLVLMARGV----NAPLSIQPD 145

Query: 153 FFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDGI-LGHTREQ 209
             +  +    D   +     + +D F   +  F VAE+  +  PV+ + DG  + HTRE 
Sbjct: 146 NLEVSFLL--DTGCMIWYAETAQDLFDMILAGFVVAEQPDVHVPVITVVDGFFVSHTRET 203

Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLR 269
           + +P PD++ +     P N   A +P  D     VPP      G F            LR
Sbjct: 204 VMLP-PDDIALP----PYNPYRAPMPVIDAE---VPP------GRF------------LR 237

Query: 270 DVYTQE-------VHDKLVRRIHRKIEQNREVYEKY-----EEYYTDDAEILVVSWGVSA 317
           D +  +        H      +   IE++R   + Y     E +   +A+++ V+ G ++
Sbjct: 238 DPFVMKSNYISYATHASWQWEVRAAIERSRPYAKHYLRGLIEHFGDPEADLVFVACGTAS 297

Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN-LGQMILEVQR 376
             +  AV     EGI   +   KT+ PFP E +RE  K  + I VPE N +G +  EV+R
Sbjct: 298 AQAKEAVRMLEDEGISARVVKLKTIRPFPIEELREATKGAKYIFVPEFNVVGWLEREVRR 357

Query: 377 FV--NDDVLLKGVNKI-GGVPLTVEEILREI 404
           ++  +    + G  ++ GG+ +  E I+RE+
Sbjct: 358 YLYGHSSAEIIGAPRVAGGMTMPAEVIVREV 388


>sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|7449945|pir||E69099 pyruvate synthase (EC
           1.2.7.1) alpha chain - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622870|gb|AAB86209.1| (AE000929) pyruvate
           oxidoreductase, alpha subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 383
           
 Score =  104 bits (256), Expect = 3e-21
 Identities = 102/378 (26%), Positives = 172/378 (44%), Gaps = 37/378 (9%)

Query: 40  DEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAMVGA 97
           ++AVA  A  A  +    YPITP + I+E +A+ +   ++   Y+++E E ++++A VGA
Sbjct: 9   NQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFVADGELKAEYIRVESEHSAMSACVGA 68

Query: 98  SWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQAR 157
           S  G++V TATS  G +LM E +  A     P+V+ +  R+  S   +    Q D    R
Sbjct: 69  SGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRA-LSAPLSIWNDQQDSIAER 127

Query: 158 WGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIRIPD 214
                D   + I   S ++A    + ++ V+E   +  P +V  DG IL HT E + IP 
Sbjct: 128 -----DSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEPVDIPS 182

Query: 215 PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQ 274
            ++V+     LP+ + +  L   +P   G    P     Y+        K          
Sbjct: 183 QEDVDSF---LPEFQPQVMLDPDEPMSLGTFTDP----DYYMEARYEVEK--------AM 227

Query: 275 EVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGI 332
           E   K++ R  R+  +   RE Y   EEY  +DAEI++V+ G         + + R +G 
Sbjct: 228 ERSRKIIERACREFSEMFGRE-YGLVEEYRCEDAEIILVAMGSVCSTLREVIDELRDKGK 286

Query: 333 KVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-----GQMILEVQRFVNDDVLLKGV 387
            VGL   +   PFP E ++   +    + V + N+     G +  E+   + D  +   +
Sbjct: 287 AVGLLKVRVHRPFPAEEIKSAVRNASKVAVLDKNITFSVGGALYTEISALLRDREVYGFI 346

Query: 388 NKIGG---VPLTVEEILR 402
             +GG    P  +EEI+R
Sbjct: 347 VGLGGRDITPAHIEEIVR 364


>sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|11280155|pir||T45088 pyruvate synthase (EC
           1.2.7.1) alpha-2 chain [imported] - Pyrococcus furiosus
           >gi|1197363|emb|CAA59505.1| (X85250) pyruvate ferredoxin
           oxidoreductase alpha-2 [Pyrococcus furiosus]
           Length = 396
           
 Score =  103 bits (255), Expect = 3e-21
 Identities = 96/336 (28%), Positives = 155/336 (45%), Gaps = 24/336 (7%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           M  +EA A+ A  A  +  A +PITPS+ I E ++  +   ++   ++++E E ++I+A 
Sbjct: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAISAC 66

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
           VGA+  G++  TAT+  G +LM E L  A     P+V+    R+  +        Q    
Sbjct: 67  VGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211
           Q   G       +     + ++A    + A+ VAE  R+  P +V FD  IL HT E + 
Sbjct: 127 QRDTGW------MQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180

Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271
           IPD + V+         E E +  + DP      P+      +  H   S +      + 
Sbjct: 181 IPDQEVVDEFL-----GEYEPKHAYIDP----ARPITQGSLAFPAHYMESRYTVWEAME- 230

Query: 272 YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG 331
             ++V D+      +K  +    Y+K EEY T+DA+I+ V+ G  A      + K R+EG
Sbjct: 231 RAKKVIDEAFAEFEKKFGRK---YQKIEEYKTEDADIIFVTMGSLAGTLNEWIDKKREEG 287

Query: 332 IKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367
            KVG        PFP E +REL KK + +   E N+
Sbjct: 288 YKVGAAKITVYRPFPVEEIRELAKKAKVLAFLEKNI 323


>gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-2) [Sulfolobus solfataricus]
           Length = 400
           
 Score =  100 bits (246), Expect = 4e-20
 Identities = 102/385 (26%), Positives = 182/385 (46%), Gaps = 48/385 (12%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVG 96
           G+EAVA G   A       YPITP + I E +A  R   ++    +++E E +++AA  G
Sbjct: 8   GNEAVALGVKLARVGVTGIYPITPQTTIIEKLAEMRAKGEIETEIVRVESEHSAMAATFG 67

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156
           A+  G++  TAT+  G   M E + +   +  P+V+V         G    GA  +    
Sbjct: 68  AALGGVRAFTATASQGLLYMHEMVWWVAGSRVPVVMV--------VGTRAVGAPWNI--- 116

Query: 157 RWGTHGDHP-------IVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHT 206
            W  H D         I+A +  + ++A   T++AF ++E  R+  P+++  DG IL HT
Sbjct: 117 -WNEHTDFTSERDSGWIMAFAS-NPQEALDLTLQAFRISEDERVFLPMMIGMDGFILSHT 174

Query: 207 REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDG--VPPMPLFGHGYFTHVTGSTHK 264
           +  + IPD D+V+     LP   +   +   DP G G   PP      GY         +
Sbjct: 175 KTNVLIPDQDQVDDF---LPPRRQPYVIDPEDPVGMGNIFPP-----EGYMR-----LRE 221

Query: 265 ENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAV 324
              L    +++V  ++ R  ++KI    +       Y  +DA+  VV  G  A  ++ AV
Sbjct: 222 SIDLALRNSEDVIKEIGREYNKKINPLGDYSTLNVSYKLEDADYAVVLMGAWAGDAMEAV 281

Query: 325 LKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL------GQMILEVQRFV 378
              R++GIK+G+   + + P+  + +R   K  +A+LV + +       G + +E++  +
Sbjct: 282 DTLREKGIKIGMLRIRYLRPWSEKEIRNTLKDKKAVLVLDRSTSFGRGGGPLYVEIKSTI 341

Query: 379 NDDV-LLKG-VNKIGGVPLTVEEIL 401
           ++ V  +KG V+ +GGV +   +++
Sbjct: 342 SNVVPQIKGVVSGLGGVTVNKNDLV 366


>emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin oxidoreductase
           alpha-2 chain [Thermoplasma acidophilum]
           Length = 402
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 93/351 (26%), Positives = 155/351 (43%), Gaps = 32/351 (9%)

Query: 15  IRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMAREL 74
           IRGD  +     R +       M G++AVAYGA  A  +F + YPITP + I E +A  +
Sbjct: 6   IRGDRMKSVNEFRTI-------MTGNDAVAYGAKLARVKFISAYPITPQTTIVEKLASMI 58

Query: 75  --PKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVL 132
              ++   Y+++E E +++AA+  +  TG++  TATS  G   M E L +      P+V+
Sbjct: 59  ANDELDAKYVEVESEHSALAAVFASELTGVRSYTATSSHGLLYMHEMLHWVAGQRLPIVM 118

Query: 133 VDVQRS-GPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER- 190
             V R+ GP         Q D    R     D   + +   S ++A    I  + +AE  
Sbjct: 119 SVVNRAIGPPWN--IWADQSDTINQR-----DTGWMQVYSESNQEAMDTIIMGYKIAENS 171

Query: 191 -LRTPVVVLFDG-ILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMP 248
            +  P++ + D  IL HT E + + D D   +V   LP  + + R+   +P G G    P
Sbjct: 172 GVMLPLMSMEDAFILSHTSEPVTMRDQD---LVNEYLPDLDLKFRIDPENPMGYGSYDTP 228

Query: 249 LFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEI 308
                +           N  R V  +E      ++ +   E N       E Y  DDA+ 
Sbjct: 229 --DGSFMEFKKDMIDSMNNARKVIKEE-----TQKFNEMFETNYGAL--IERYRMDDADY 279

Query: 309 LVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRA 359
            +++ G  A  +   + + R+ G+ +GL   +   PFP + + E  K V++
Sbjct: 280 AIIAMGTVASTARFVIDRLRENGLNIGLIRIRYFRPFPYDEILEDLKNVKS 330


>pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
           >gi|2983615|gb|AAC07184.1| (AE000726) ferredoxin
           oxidoreductase alpha subunit [Aquifex aeolicus]
           Length = 389
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 105/381 (27%), Positives = 163/381 (42%), Gaps = 39/381 (10%)

Query: 36  FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGY---YLQMEDEIASIA 92
           F+ G +A A     A       YPITP SE    +     +  GY   Y + E+E  +++
Sbjct: 22  FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ--GYVKDYYRAEEEYGAMS 79

Query: 93  AMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGD 152
           A+ GA   G +  TATSGPG     E +        P VL  + R       A    Q D
Sbjct: 80  AIAGAVRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLGVMTR----VVNAPLSIQPD 135

Query: 153 FFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRT--PVVVLFDGI-LGHTREQ 209
             +  +  +    +V +   + +D F  T+  F ++E++    PVVV  +G  + H +  
Sbjct: 136 NVEISYLLNSG--LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193

Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPP----MPLFGHGYFTHVTGSTHKE 265
           + +P                E+ +LP  DP+   VPP    +P         V  S    
Sbjct: 194 VELPP---------------EDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238

Query: 266 NGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVL 325
             +  V+ QEV         R  +  +       E    DAE+ VV+ G +A     A  
Sbjct: 239 YLIHAVWQQEVWSAN----RRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQR 294

Query: 326 KARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-GQMILEVQRFV-NDDVL 383
            A  EG+ VGL   K++ PFP + +RE  K  +A++VPE N+ G +  EV+  + N  ++
Sbjct: 295 YATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIV 354

Query: 384 LKGVNKIGGVPLTVEEILREI 404
           + G    GG+ L VE I+ EI
Sbjct: 355 VDGPRVYGGMTLPVELIMEEI 375


>gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-1) [Sulfolobus solfataricus]
           Length = 385
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 88/331 (26%), Positives = 153/331 (45%), Gaps = 25/331 (7%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           ++G+ AVAY    A  +  A +PITP + + E ++  +   ++    +++E E +++A++
Sbjct: 11  LVGNHAVAYAVKQAKPKVLAVFPITPQTTMLEKLSEYISSEELKAELIKVESEHSALASI 70

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
            GA+  G +V TATS  G   M E + +A     P+V     R+           Q DF 
Sbjct: 71  YGAALAGARVFTATSSQGLLYMTEMIYWAGGQRVPIVAAVATRAIAEPWSIWDDHQ-DFV 129

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211
             R     D   + I   +V++A+  TI+AF ++E  R+  PV++ FDG IL HT E+I 
Sbjct: 130 SKR-----DAIWIQIMAENVQEAYDMTIQAFRISEDERVILPVMMGFDGFILTHTMERIE 184

Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271
           + + +EV+     LP  +    + F DP   G    P     Y      +  +  G+ + 
Sbjct: 185 VLEDNEVD---NFLPPRQFNL-IDFSDPIAIGPIATPEEYIKYRYEAMKAMERAKGVIEE 240

Query: 272 YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG 331
              E      R+ H  +E           Y  +DA+ + V+ G  +     AV + R  G
Sbjct: 241 IMGEYERISGRKQHGLVEC----------YKCEDAKYVFVTMGAWSGDGKAAVDRLRDSG 290

Query: 332 IKVGLFVPKTVHPFPGERMRELGKKVRAILV 362
           +K GL   +   PFP E++ E  + ++ ++V
Sbjct: 291 VKTGLLKIRVFRPFPKEKVEEYLRSMKGVVV 321


>gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA)
           [Archaeoglobus fulgidus] >gi|7449955|pir||D69506
           probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC
           1.2.7.-) alpha chain AF2053 [similarity] - Archaeoglobus
           fulgidus >gi|2648476|gb|AAB89196.1| (AE000961)
           2-ketoisovalerate ferredoxin oxidoreductase, subunit
           alpha (vorA) [Archaeoglobus fulgidus]
           Length = 366
           
 Score = 96.3 bits (236), Expect = 6e-19
 Identities = 100/383 (26%), Positives = 168/383 (43%), Gaps = 71/383 (18%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           +  +EA+A     A     A YPITP S I E ++  +   ++   ++++E E +++  +
Sbjct: 17  LTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHSAMGVV 76

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
           +GA+  G +V TATS  G + M E   +A  +  P+V+    RS                
Sbjct: 77  IGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAARS---------------I 121

Query: 155 QARWGTHGDHP----------IVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGI-L 203
            A W  HGDH           I++++  + ++AF  T+ AF ++E +  PV V  DG  +
Sbjct: 122 GAPWNIHGDHLDLMAMRDLGWIISVAE-NAQEAFDMTLNAFMLSEEVNIPVAVAIDGFTM 180

Query: 204 GHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTH 263
            HT E + +    EVEI     P  ++  R+         +P M +              
Sbjct: 181 SHTAEVVEV---REVEI-----PPRKQAYRI---------LPGMDV-------------- 209

Query: 264 KENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEK-----YEEYYTDDAEILVVSWGVSAR 318
               L  V   E        + + +E + E+ EK      E Y  +DA+  VV  G  + 
Sbjct: 210 ---ALNAVTFGEARMTARYDLAKDLENSAELIEKEYGGLVERYRLEDADYAVVVTGGLSG 266

Query: 319 PSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-GQMILEVQRF 377
               AV   R+EG+K+G+   K + PFP + ++ L  +V  +     +L G + +EV   
Sbjct: 267 DVKDAVDMLREEGVKMGVLRLKFIRPFPKKAVKSLPSQVLVVDRANTDLRGTLSVEVAAC 326

Query: 378 VNDDVLLKGVNKIGGVPLTVEEI 400
             ++V +  V  IGG   TVEE+
Sbjct: 327 GVENVNV--VAGIGGRYPTVEEL 347


>gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alpha subunit [Methanococcus
           maripaludis]
           Length = 387
           
 Score = 95.6 bits (234), Expect = 9e-19
 Identities = 93/381 (24%), Positives = 161/381 (41%), Gaps = 42/381 (11%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAMVG 96
           G  A A  A  A     A YPITP +   E +A  +   ++   Y+++E E ++++A +G
Sbjct: 9   GTSAAAEAAKLADVDVIAAYPITPQTTCVEKLADFVANGELNAEYIKVESEHSAMSASIG 68

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156
           AS  G +  TATS  G +LM E L  A     P+V+++  R+  +        Q    Q 
Sbjct: 69  ASAAGARAFTATSSQGLALMHEVLFAAAGMRVPVVMMNANRALSAPINIWNDQQDSLSQR 128

Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVA--ERLRTPVVVLFDG-ILGHTREQIRIP 213
             G       + +     ++     I+AF +A  E++  PV+V  DG IL HT E + +P
Sbjct: 129 DTGW------IQLYAEDNQEVLDLVIQAFKIAEDEKVLLPVMVNLDGFILTHTVEPVTLP 182

Query: 214 DPDEV-------EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKEN 266
             + V       E  +  L   +   +   GDP+           +   T     T  EN
Sbjct: 183 KQENVLDFIGTYEPKHAYLDPKKPMTQGALGDPN-----------YYMETRYAIETAMEN 231

Query: 267 GLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLK 326
             + +   +VHD    + +R            E Y  + AE ++V+ G         +  
Sbjct: 232 AKKVI--ADVHDAFAEKFNRAYGNG-----LIESYNLEKAENVIVAMGSICGTIKDMIDL 284

Query: 327 ARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPE------MNLGQMILEVQRFVND 380
            +KEG+++GL   +   P P E +++  K  + + + +      MN G +  +V   + D
Sbjct: 285 KKKEGVEIGLLKIRCYRPLPIEMIKDALKNAKNVAILDKSISLGMNKGAIYADVASHLKD 344

Query: 381 DVLLKGVNKIGGVPLTVEEIL 401
              +  +  +GG  +T E+IL
Sbjct: 345 KKTVNYIVGLGGRDITPEDIL 365


>pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
           >gi|2983644|gb|AAC07211.1| (AE000728) ferredoxin
           oxidoreductase alpha subunit [Aquifex aeolicus]
           Length = 404
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 106/392 (27%), Positives = 166/392 (42%), Gaps = 51/392 (13%)

Query: 35  YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVG--GYYLQMEDEIASIA 92
           +F+ G EAV   A  A       YPITP SE A  M  EL + G  G Y + E E   ++
Sbjct: 34  HFITGSEAVKEAAKRASVDASISYPITPQSEAAH-MLGELWREGYIGVYFRGESEFGVMS 92

Query: 93  AMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGD 152
            + G +  G + +T TSGPG     E       +  P+ LV + R   S           
Sbjct: 93  EVAGCAMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMARGINSPLSIQPDNLEI 152

Query: 153 FFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDGI-LGHTREQ 209
            F    G    H   A      ++ F   I  F VAE+  +  P++   DG  + HTRE 
Sbjct: 153 SFLLDTGCMVWHAETA------QELFDMIIAGFVVAEQPDVHVPIITAIDGFFISHTREA 206

Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGD---PHGDGVPPMPLFGHGYFTHVTGSTHKEN 266
           + +P P+++ +     P N  +A +P  D   P G  +    +    Y ++ T       
Sbjct: 207 VYLP-PEDIALP----PYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISYAT------- 254

Query: 267 GLRDVYTQEVHDKLVRRIHRKIEQNREVYEKY-----EEYYTDDAEILVVSWGVSARPSL 321
                     H      +   IE++R   + Y     E +   + E+L ++ G +A  + 
Sbjct: 255 ----------HASWQFEVRAAIERSRPYAKHYLRGLVEHFGDPEGEVLFIASGTAAAQAK 304

Query: 322 GAV-LKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN-LGQMILEVQR--F 377
            A  +   +EGIK  +   KT+ PFP E +RE  K  + I +PE N +G +  EV+R  +
Sbjct: 305 EATQILIHEEGIKARVLRLKTLRPFPTEEVREAVKGAKYIFIPEFNVVGWLEREVKRALY 364

Query: 378 VNDDVLLKGVNKIGG-----VPLTVEEILREI 404
              D+ + G  ++GG         V+E+LR I
Sbjct: 365 GYTDIPIFGTPRVGGGMTMPPEFIVQEVLRLI 396


>pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicobacter pylori
           (strain 26695) >gi|2314261|gb|AAD08154.1| (AE000617)
           pyruvate ferredoxin oxidoreductase, alpha subunit
           [Helicobacter pylori 26695]
           Length = 407
           
 Score = 94.0 bits (230), Expect = 3e-18
 Identities = 90/330 (27%), Positives = 156/330 (47%), Gaps = 31/330 (9%)

Query: 56  AGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGF 113
           A YPITPS+ I +     ++   V G ++ +E E A+++A VGA+  G +V TATS  G 
Sbjct: 32  AAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVGAAAAGGRVSTATSSQGL 91

Query: 114 SLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVS 173
           +LM E L  A     P+VL  V R+  +      G   D + +R     D   +++   +
Sbjct: 92  ALMVEVLYQASGMRLPIVLNLVNRA-LAAPLNIHGDHSDMYLSR-----DSGWISLCTCN 145

Query: 174 VEDAFWETIRAFNVAE--RLRTPVVVLFDGIL-GHTREQIRIPDPDEVEIVYRKLPQNE- 229
            ++A+  T+ AF +AE  ++R P +V  DG L  HT + +R   P    + Y+ + + + 
Sbjct: 146 PQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVR---PLSDAVAYQFVGEYQT 202

Query: 230 EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE 289
           + + L F  P   G      +   ++ H     H       V  +EV +   +   R+  
Sbjct: 203 KHSLLDFDKPVSYGAQAEEEW---HYEHKAQLHHAIMSASSVI-EEVFNDFAKLTGRQ-- 256

Query: 290 QNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGER 349
                Y   + +  +DAEI + + G +   ++ A  + RK+GIK G+    ++ PFP ER
Sbjct: 257 -----YHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311

Query: 350 MRELGKKVRAILV-----PEMNLGQMILEV 374
           + +  K ++A+ +     P   +G M  EV
Sbjct: 312 LGQDLKNLKALAILDKSSPAGTMGAMFNEV 341


>pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter pylori  (strain
           J99) >gi|4155626|gb|AAD06616.1| (AE001531) Pyruvate
           ferrodoxin oxidoreductase [Helicobacter pylori J99]
           Length = 407
           
 Score = 93.2 bits (228), Expect = 5e-18
 Identities = 90/330 (27%), Positives = 156/330 (47%), Gaps = 31/330 (9%)

Query: 56  AGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGF 113
           A YPITPS+ I +     ++   V G ++ +E E A+++A VGA+  G +V TATS  G 
Sbjct: 32  AAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVGAAAAGGRVSTATSSQGL 91

Query: 114 SLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVS 173
           +LM E L  A     P+VL  V R+  +      G   D + +R     D   +++   +
Sbjct: 92  ALMVEVLYQASGMRLPIVLNLVNRA-LAAPLNIHGDHSDMYLSR-----DSGWISLCTCN 145

Query: 174 VEDAFWETIRAFNVAE--RLRTPVVVLFDGIL-GHTREQIRIPDPDEVEIVYRKLPQNE- 229
            ++A+  T+ AF +AE  ++R P +V  DG L  HT + +R   P    + Y+ + + + 
Sbjct: 146 PQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVR---PLSDAVAYQFVGEYQT 202

Query: 230 EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE 289
           + + L F  P   G      +   ++ H     H       V  +EV +   +   R+  
Sbjct: 203 KHSLLDFDKPVSYGAQAEEEW---HYEHKAQLHHAIMSASSVI-EEVFNDFAKLTGRQ-- 256

Query: 290 QNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGER 349
                Y   + +  +DAEI + + G +   ++ A  + RK+GIK G+    ++ PFP ER
Sbjct: 257 -----YHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311

Query: 350 MRELGKKVRAILV-----PEMNLGQMILEV 374
           + +  K ++A+ +     P   +G M  EV
Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEV 341


>gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit
           [Helicobacter pylori]
           Length = 396
           
 Score = 91.7 bits (224), Expect = 1e-17
 Identities = 88/330 (26%), Positives = 155/330 (46%), Gaps = 31/330 (9%)

Query: 56  AGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGF 113
           A YPITPS+ I +     ++   + G ++ +E E A+++A VGA+  G +V TATS  G 
Sbjct: 32  AAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMSACVGAAAAGGRVSTATSSQGL 91

Query: 114 SLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVS 173
           +LM E L  A     P+VL  V R+  +      G   D + +R     D   +++   +
Sbjct: 92  ALMVEVLYQASGMRLPIVLNLVNRA-LAAPLNIHGDHSDMYLSR-----DSGWISLCTCN 145

Query: 174 VEDAFWETIRAFNVAE--RLRTPVVVLFDGIL-GHTREQIRIPDPDEVEIVYRKLPQNE- 229
            ++A+  T+ AF +AE  ++R P +V  DG L  HT + +R   P    + Y+ + + + 
Sbjct: 146 PQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCSHTVQNVR---PLSDAVAYQFVGEYQT 202

Query: 230 EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE 289
           + + L F  P   G          ++ H     H       V  +EV +   +   R+  
Sbjct: 203 KHSLLDFDKPVSYGAQAEE---EWHYEHKAQLHHAIMSASSV-IEEVFNDFAKLTGRQ-- 256

Query: 290 QNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGER 349
                Y   + +  +DAEI + + G +   ++ A  + RK+GIK G+    ++ PFP E+
Sbjct: 257 -----YHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYEK 311

Query: 350 MRELGKKVRAILV-----PEMNLGQMILEV 374
           + +  K ++A+ +     P   +G M  EV
Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEV 341


>emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase
           [Thermotoga maritima]
           >gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate
           ferredoxin oxidoreductase, alpha subunit [Thermotoga
           maritima]
           Length = 394
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 101/340 (29%), Positives = 150/340 (43%), Gaps = 32/340 (9%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPK--VGGYYLQMEDEIASIAAMVG 96
           G EAVA           A YPITP + I E  AR +    V    + +E E ++++A+VG
Sbjct: 14  GAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAVVG 73

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQR--SGPSTGQATKGAQGDFF 154
           A+  G + MTATS  G +LM E +  A     P+V+  V R  SGP           D  
Sbjct: 74  AAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCD---HSDAM 130

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDG-ILGHTREQIR 211
             R     D   + +   + ++A+  TI A  +AE   +R PV+V  DG IL H  E + 
Sbjct: 131 AER-----DSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVE 185

Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGD-PHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270
              PDE+     K    E +   P  D  H     P+ L+ + YF H          ++ 
Sbjct: 186 F-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDY-YFEHKRQQIEAMENVKK 239

Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330
           V+  E+  +      RK       Y   E Y  +DAE ++V+ G +       V + R+E
Sbjct: 240 VF-PEIAKEFEETFGRK-------YWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREE 291

Query: 331 GIKVGLFVPKTVHPFPGERMREL--GKKVRAILVPEMNLG 368
           G KVG        PFP E+++EL  G+K   +L   ++ G
Sbjct: 292 GYKVGSLKIWMFRPFPKEQLQELLNGRKSVVVLDRAVSFG 331


>sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|7449946|pir||C72427 pyruvate synthase (EC
           1.2.7.1) alpha chain - Thermotoga maritima (strain MSB8)
           Length = 392
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 101/340 (29%), Positives = 150/340 (43%), Gaps = 32/340 (9%)

Query: 39  GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPK--VGGYYLQMEDEIASIAAMVG 96
           G EAVA           A YPITP + I E  AR +    V    + +E E ++++A+VG
Sbjct: 12  GAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAVVG 71

Query: 97  ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQR--SGPSTGQATKGAQGDFF 154
           A+  G + MTATS  G +LM E +  A     P+V+  V R  SGP           D  
Sbjct: 72  AAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCD---HSDAM 128

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDG-ILGHTREQIR 211
             R     D   + +   + ++A+  TI A  +AE   +R PV+V  DG IL H  E + 
Sbjct: 129 AER-----DSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVE 183

Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGD-PHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270
              PDE+     K    E +   P  D  H     P+ L+ + YF H          ++ 
Sbjct: 184 F-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDY-YFEHKRQQIEAMENVKK 237

Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330
           V+  E+  +      RK       Y   E Y  +DAE ++V+ G +       V + R+E
Sbjct: 238 VF-PEIAKEFEETFGRK-------YWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREE 289

Query: 331 GIKVGLFVPKTVHPFPGERMREL--GKKVRAILVPEMNLG 368
           G KVG        PFP E+++EL  G+K   +L   ++ G
Sbjct: 290 GYKVGSLKIWMFRPFPKEQLQELLNGRKSVVVLDRAVSFG 329


>gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta subunit [Prevotella
           albensis]
           Length = 104
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 41/88 (46%), Positives = 54/88 (60%), Gaps = 2/88 (2%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           M G+EA+A+ AI  G   + GYPITP SEI ET+A   P    G   LQ E E+ASI  +
Sbjct: 8   MKGNEAIAHAAIRCGADGFFGYPITPQSEIIETLALLKPWETTGMVVLQAESEVASINML 67

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGY 122
            G +  G +V+T +S PG +LMQE + Y
Sbjct: 68  YGGAGAGKRVLTTSSSPGVALMQEGIAY 95


>gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-like) [Sulfolobus solfataricus]
           Length = 415
           
 Score = 75.7 bits (183), Expect = 9e-13
 Identities = 87/408 (21%), Positives = 169/408 (41%), Gaps = 69/408 (16%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           M G +AVA+ A++A     A YPI P +E+ +T+++ +   ++   ++  E E      +
Sbjct: 14  MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
             AS  G + +  +SG G+    E +        P+V +   R+    G A      D  
Sbjct: 74  KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPG-AYGVEHNDAL 132

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211
             R     D   + +   + ++AF   + A+ +AE  R+  P+ +  DG  L H+ + +R
Sbjct: 133 MVR-----DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187

Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271
           +P         R+L +N       F  P+  G          Y  H          + + 
Sbjct: 188 LPP--------RELVKN-------FLPPYNRGK---------YLVHPDNPITVAPQVNED 223

Query: 272 YTQEV---HDKLVRRIHRKI----EQNREVYEKY---------------EEYYTDDAEIL 309
           +  E+   H++ + R    I    E+ ++V+ +Y               E Y  DDAE++
Sbjct: 224 WVMEIRRQHEEAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVV 283

Query: 310 VVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEM---- 365
           ++  G  ++P   A+   R++G KVG+   +   PFP + +       R + V +     
Sbjct: 284 LIGMGTVSKPMKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSM 343

Query: 366 ---NLGQMILEVQRFVNDDV-----LLKGVNKIGGVPLTVEEILREIR 405
              N G +I    R    D+     ++  +  +GG  +T++++ + I+
Sbjct: 344 GSPNRGGVIYHEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391


>pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolobus
           solfataricus >gi|1707735|emb|CAA69455.1| (Y08256)
           pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus
           solfataricus]
           Length = 415
           
 Score = 75.7 bits (183), Expect = 9e-13
 Identities = 87/408 (21%), Positives = 169/408 (41%), Gaps = 69/408 (16%)

Query: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94
           M G +AVA+ A++A     A YPI P +E+ +T+++ +   ++   ++  E E      +
Sbjct: 14  MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73

Query: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154
             AS  G + +  +SG G+    E +        P+V +   R+    G A      D  
Sbjct: 74  KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPG-AYGVEHNDAL 132

Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211
             R     D   + +   + ++AF   + A+ +AE  R+  P+ +  DG  L H+ + +R
Sbjct: 133 MVR-----DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187

Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271
           +P         R+L +N       F  P+  G          Y  H          + + 
Sbjct: 188 LPP--------RELVKN-------FLPPYNRGK---------YLVHPDNPITVAPQVNED 223

Query: 272 YTQEV---HDKLVRRIHRKI----EQNREVYEKY---------------EEYYTDDAEIL 309
           +  E+   H++ + R    I    E+ ++V+ +Y               E Y  DDAE++
Sbjct: 224 WVMEIRRQHEEAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVV 283

Query: 310 VVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEM---- 365
           ++  G  ++P   A+   R++G KVG+   +   PFP + +       R + V +     
Sbjct: 284 LIGMGTVSKPMKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSM 343

Query: 366 ---NLGQMILEVQRFVNDDV-----LLKGVNKIGGVPLTVEEILREIR 405
              N G +I    R    D+     ++  +  +GG  +T++++ + I+
Sbjct: 344 GSPNRGGVIYHEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391


>pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alpha  (iora-1)
           PAB0855 - Pyrococcus abyssi (strain Orsay)
           >gi|5458715|emb|CAB50202.1| (AJ248287) indolepyruvate
           ferredoxin oxidoreductase, subunit alpha (iorA-1)
           [Pyrococcus abyssi]
           Length = 648
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 58/209 (27%), Positives = 92/209 (43%), Gaps = 17/209 (8%)

Query: 31  KPGN-YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIA 89
           KPG    ++G++A+  GA+      YA YP TPSSEI +TMA    + G Y     +E  
Sbjct: 12  KPGERVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAAVASRAGVYMEYSTNEKV 71

Query: 90  SIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGA 149
           +    + ASW GL+ MTA    G ++  ++            LV V    PS   +++  
Sbjct: 72  AFETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGVNGGLVVVVADDPSM-WSSQNE 130

Query: 150 QGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQ 209
           Q     A++       I  + P SV++A      AF ++E+    V++       H R  
Sbjct: 131 QDTRAIAKFAN-----IPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG- 184

Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGD 238
                    ++V  +LPQ  +E +  FGD
Sbjct: 185 ---------DVVLGELPQEIKEGKRKFGD 204


>sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE
           FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           >gi|7450338|pir||F71124 probable indolepyruvate
           ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3257173|dbj|BAA29856.1| (AP000003) 648aa
           long hypothetical indolepyruvate ferredoxin
           oxidoreductase alpha subunit [Pyrococcus horikoshii]
           Length = 648
           
 Score = 69.1 bits (166), Expect = 9e-11
 Identities = 57/209 (27%), Positives = 92/209 (43%), Gaps = 17/209 (8%)

Query: 31  KPGN-YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIA 89
           KPG    ++G++A+  GA+      YA YP TPSSEI +TMA    K G Y     +E  
Sbjct: 12  KPGEKVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAMVAKKAGVYMEYSTNEKV 71

Query: 90  SIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGA 149
           +    + ASW GL+ MTA    G ++  ++            L+ V    PS   +++  
Sbjct: 72  AFETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGINGGLIVVVADDPSM-WSSQNE 130

Query: 150 QGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQ 209
           Q     A++       I  + P SV++A      AF ++E+    V++       H R  
Sbjct: 131 QDTRAIAKFAN-----IPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG- 184

Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGD 238
                    ++V  +LPQ  +E +  FG+
Sbjct: 185 ---------DVVLGELPQEIKEGKRKFGN 204


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.140    0.417 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 165402996
Number of Sequences: 2977
Number of extensions: 7505885
Number of successful extensions: 15791
Number of sequences better than 1.0e-10: 60
Number of HSP's better than  0.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 15648
Number of HSP's gapped (non-prelim): 64
length of query: 408
length of database: 189,106,746
effective HSP length: 54
effective length of query: 354
effective length of database: 156,788,448
effective search space: 55503110592
effective search space used: 55503110592
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)