BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB2359 (korA-1) DE:2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-1) (408 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 837 0.0 pir||B71047 probable ferredoxin oxidoreductase alpha subunit - P... 790 0.0 pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 437 e-121 pir||F71046 probable ferredoxin oxidoreductase alpha subunit - P... 435 e-121 sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 373 e-102 pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 358 7e-98 sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 358 7e-98 pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 351 9e-96 pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 282 6e-75 gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit a... 279 4e-74 pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 268 1e-70 pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacte... 266 3e-70 gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:accepto... 257 2e-67 pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (s... 246 4e-64 dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Baci... 204 1e-51 sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB... 202 5e-51 pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 202 5e-51 gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, su... 200 2e-50 pir||F70864 probable oxidoreductase alpha subunit - Mycobacteriu... 190 3e-47 emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit... 186 3e-46 emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces... 186 3e-46 pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha ... 180 3e-44 pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validate... 176 4e-43 gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin ox... 176 4e-43 emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidore... 176 4e-43 emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidored... 168 1e-40 pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha... 167 2e-40 gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain... 162 5e-39 pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit -... 153 4e-36 pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 143 4e-33 pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 141 2e-32 emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma a... 138 2e-31 gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (... 123 3e-27 pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase... 113 4e-24 sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 109 7e-23 pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 -... 108 2e-22 pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit -... 107 2e-22 sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 106 4e-22 pir||A71114 probable ferredoxin oxidoreductase alpha subunit - P... 106 5e-22 sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 106 6e-22 dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase al... 106 6e-22 sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 104 3e-21 sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 103 3e-21 gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 100 4e-20 emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin ox... 99 1e-19 pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 98 2e-19 gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 97 4e-19 gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit... 96 6e-19 gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alph... 96 9e-19 pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 94 2e-18 pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicob... 94 3e-18 pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter py... 93 5e-18 gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alp... 92 1e-17 emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin ox... 83 5e-15 sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 83 5e-15 gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta s... 77 4e-13 gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 76 9e-13 pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolo... 76 9e-13 pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alph... 71 3e-11 sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA ... 69 9e-11 >pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-1) PAB2359 - Pyrococcus abyssi (strain Orsay) >gi|5457936|emb|CAB49426.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-1) [Pyrococcus abyssi] Length = 408 Score = 837 bits (2138), Expect = 0.0 Identities = 408/408 (100%), Positives = 408/408 (100%) Query: 1 MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI 60 MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI Sbjct: 1 MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI 60 Query: 61 TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL 120 TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL Sbjct: 61 TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL 120 Query: 121 GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE 180 GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE Sbjct: 121 GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE 180 Query: 181 TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH 240 TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH Sbjct: 181 TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH 240 Query: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE 300 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE Sbjct: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE 300 Query: 301 YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360 YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI Sbjct: 301 YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360 Query: 361 LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA 408 LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA Sbjct: 361 LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA 408 >pir||B71047 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3258095|dbj|BAA30778.1| (AP000006) 408aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 408 Score = 790 bits (2018), Expect = 0.0 Identities = 376/408 (92%), Positives = 398/408 (97%) Query: 1 MPRFCHSCKVVGMIIRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPI 60 M R C+S KVV MIIRGDEPEQK LLRKLY+PGNYFMMGDEA+AYGAIFAGCRFYAGYPI Sbjct: 1 MSRLCNSRKVVVMIIRGDEPEQKALLRKLYRPGNYFMMGDEAIAYGAIFAGCRFYAGYPI 60 Query: 61 TPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENL 120 TPSSEIAETMARELPKVGGYYLQMEDEI SIAAM+GASWTGLK MTATSGPGFSLMQEN+ Sbjct: 61 TPSSEIAETMARELPKVGGYYLQMEDEIGSIAAMIGASWTGLKAMTATSGPGFSLMQENI 120 Query: 121 GYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWE 180 GYAVMTETP+V+V+VQRSGPSTGQATKGAQGDFFQARWGTHGDHP++A+SP+SVEDAFWE Sbjct: 121 GYAVMTETPIVVVNVQRSGPSTGQATKGAQGDFFQARWGTHGDHPMIAVSPISVEDAFWE 180 Query: 181 TIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPH 240 TIRAFN+AE+LRTPV+VLFDGILGHTREQIRIPDPDEVEI YRKLP +EEEA+LPFGDPH Sbjct: 181 TIRAFNIAEKLRTPVIVLFDGILGHTREQIRIPDPDEVEITYRKLPGSEEEAKLPFGDPH 240 Query: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE 300 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNR+VYEKYEE Sbjct: 241 GDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNRDVYEKYEE 300 Query: 301 YYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360 YYTDDAEILVVSWGVSARPSLGAVLKAR+EGIK GLFVPKTVHPFPGERMRELGKKVRAI Sbjct: 301 YYTDDAEILVVSWGVSARPSLGAVLKAREEGIKAGLFVPKTVHPFPGERMRELGKKVRAI 360 Query: 361 LVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGVA 408 LVPEMNLGQM+LEVQRFVNDDV+LKGVNKIGGVPLTVEEIL+EIRGVA Sbjct: 361 LVPEMNLGQMVLEVQRFVNDDVILKGVNKIGGVPLTVEEILKEIRGVA 408 >pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-2) PAB0346 - Pyrococcus abyssi (strain Orsay) >gi|5457939|emb|CAB49429.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-2) [Pyrococcus abyssi] Length = 385 Score = 437 bits (1111), Expect = e-121 Identities = 217/370 (58%), Positives = 273/370 (73%) Query: 36 FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95 F+ GDEA+A AI AGCRFYAGYPITP+SEI E MA +P V G +QMEDEIASIAA++ Sbjct: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71 Query: 96 GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155 GASW G K MTATSGPGFSLMQEN+GYAVMTETP+V+VDVQR GPSTGQ T +QGD Q Sbjct: 72 GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131 Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215 + WGTHGDH ++ +SP +V++AF TIRAFN+AE+ RTPV++L D +GH RE++ IP+P Sbjct: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 Query: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275 DE+EIV RKLPQNEEEA+LPFGDPHGD VPPMP+FG GY T+VTG TH E G +E Sbjct: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251 Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335 VH++++RRI KIE+N++ YE DDAE+ +V+ G+ AR +L A+ + R+ GIK G Sbjct: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311 Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395 L T+ PF E + ++ KV I VPEMNLGQ+ V+ N +K ++KIGG Sbjct: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 Query: 396 TVEEILREIR 405 T EI+ IR Sbjct: 372 TPMEIVDFIR 381 >pir||F71046 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3258091|dbj|BAA30774.1| (AP000006) 385aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 385 Score = 435 bits (1107), Expect = e-121 Identities = 215/370 (58%), Positives = 273/370 (73%) Query: 36 FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95 F+ GDEA+A AI AGCRFYAGYPITP+SEI E MA +P + G +QMEDEI SIAA++ Sbjct: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLIDGVVIQMEDEIGSIAAVI 71 Query: 96 GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155 GASW G+K MTATSGPGFSLMQEN+GYAVMTETP+V+V+VQR GPSTGQ T +QGD Q Sbjct: 72 GASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRGGPSTGQPTLPSQGDIMQ 131 Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215 + WGTHGDH ++ +SP +V++AF TIRAFN+AE+ RTPV++L D +GH RE++ IP+P Sbjct: 132 SIWGTHGDHTLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 Query: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275 DE+EIV RKLP +EEEA+LPFGDPHGDGVPPMP+FG GY T+VTG TH E G +E Sbjct: 192 DEIEIVNRKLPGSEEEAKLPFGDPHGDGVPPMPIFGKGYRTYVTGLTHDEKGRPRTVERE 251 Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335 VH++L+RRI KIE+N++ YE DDAEI +V+ G+ AR +L A+ + R GIK G Sbjct: 252 VHERLIRRIFEKIEKNKKDIFDYEARELDDAEIAIVTTGIVARSALRAIKELRNLGIKAG 311 Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395 L T+ PF E + ++ +KV I VPEMNLGQ+ V+ N +K ++KIGG Sbjct: 312 LLKINTIWPFDFELIEKVAEKVERIYVPEMNLGQLYHLVKEGANGKAEVKLISKIGGEVH 371 Query: 396 TVEEILREIR 405 T EI+ IR Sbjct: 372 TPMEIIDFIR 381 >sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|2127893|pir||E64334 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus jannaschii >gi|1592279|gb|AAB98264.1| (U67483) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Methanococcus jannaschii] Length = 366 Score = 373 bits (948), Expect = e-102 Identities = 200/373 (53%), Positives = 263/373 (69%), Gaps = 13/373 (3%) Query: 36 FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95 FM G++A A GAI AGCRF+AGYPITPS+EIAE MARELPKVGGYY+QMEDEI SIAA++ Sbjct: 5 FMQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELPKVGGYYIQMEDEIGSIAAVI 64 Query: 96 GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155 GASW GLK MTATSGPGFSLMQEN+G+A MTETP V+VD+QR GPSTGQ T +QGD Q Sbjct: 65 GASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQRGGPSTGQPTMASQGDMMQ 124 Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215 RWG+HGD+ ++A++P SV++ + TI AFN AE+ R PV V+ D I+GH RE++ + Sbjct: 125 CRWGSHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRIPVFVMADEIVGHMREKVIL--H 182 Query: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275 D +EI+ RK P+ E+ + P+ P +P MP+FG GY H+TG TH E G DV + E Sbjct: 183 DNIEIINRKKPE-EKPCKKPY--PFDKLIPEMPVFGEGYNVHITGLTHDERGYPDV-SPE 238 Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335 HDKLVRRI KI +N++ K+E DAEI+ V +G +R AV R++G+ VG Sbjct: 239 THDKLVRRIVNKIRKNKDEIIKWEGENL-DAEIVFVCYGSPSRTVKHAVRNLREKGLDVG 297 Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVN--DDVLLKGVNKIGGV 393 TV+PFP + +++L K + ++VPEMNLGQ+ EV+R ++V+L V+KIGG Sbjct: 298 YIRLITVYPFPDDLLKKL--KAKKVVVPEMNLGQIYYEVERVCKKAEEVIL--VDKIGGE 353 Query: 394 PLTVEEILREIRG 406 EE+ R + G Sbjct: 354 LHRPEELERAVLG 366 >pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622136|gb|AAB85529.1| (AE000875) 2-oxoglutarate oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 378 Score = 358 bits (909), Expect = 7e-98 Identities = 191/370 (51%), Positives = 247/370 (66%), Gaps = 3/370 (0%) Query: 35 YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAM 94 YF+ G++A A GAI AGCRF+AGYPITPS+EIAE MA LP+ GG ++QMEDEI ++ A+ Sbjct: 7 YFIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAV 66 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 +GA W+G++ MTATSGPGFSLMQE++GYA MTETPLV+V+VQR PSTGQ T +Q D Sbjct: 67 IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 126 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD 214 QARWG+HGD+ I+A+SP SV++ F T+RAFN+AE R PV+V+ D I+GH RE+I I Sbjct: 127 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI-- 184 Query: 215 PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQ 274 PD V+I R+ P E LPF P DGVP MP FG GY VTG TH E G D Sbjct: 185 PDRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNP 243 Query: 275 EVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKV 334 E H +LV+R+ KI ++R+ +E T+DA I V+S+G +R AV AR++G++ Sbjct: 244 EGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRA 303 Query: 335 GLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVP 394 G T PFP +R ++ +LV EMNLGQM EVQR ++ + KIGG Sbjct: 304 GYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEI 363 Query: 395 LTVEEILREI 404 EEIL I Sbjct: 364 HRPEEILNMI 373 >sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 376 Score = 358 bits (909), Expect = 7e-98 Identities = 191/370 (51%), Positives = 247/370 (66%), Gaps = 3/370 (0%) Query: 35 YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAM 94 YF+ G++A A GAI AGCRF+AGYPITPS+EIAE MA LP+ GG ++QMEDEI ++ A+ Sbjct: 5 YFIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAV 64 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 +GA W+G++ MTATSGPGFSLMQE++GYA MTETPLV+V+VQR PSTGQ T +Q D Sbjct: 65 IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 124 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD 214 QARWG+HGD+ I+A+SP SV++ F T+RAFN+AE R PV+V+ D I+GH RE+I I Sbjct: 125 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI-- 182 Query: 215 PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQ 274 PD V+I R+ P E LPF P DGVP MP FG GY VTG TH E G D Sbjct: 183 PDRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNP 241 Query: 275 EVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKV 334 E H +LV+R+ KI ++R+ +E T+DA I V+S+G +R AV AR++G++ Sbjct: 242 EGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRA 301 Query: 335 GLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVP 394 G T PFP +R ++ +LV EMNLGQM EVQR ++ + KIGG Sbjct: 302 GYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEI 361 Query: 395 LTVEEILREI 404 EEIL I Sbjct: 362 HRPEEILNMI 371 >pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain TM0878 [similarity] - Thermotoga maritima (strain MSB8) >gi|4981412|gb|AAD35959.1|AE001753_15 (AE001753) pyruvate:ferredoxin 2-oxidoreductase-related protein [Thermotoga maritima] Length = 386 Score = 351 bits (891), Expect = 9e-96 Identities = 191/374 (51%), Positives = 247/374 (65%), Gaps = 5/374 (1%) Query: 32 PGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASI 91 P F+ G+EA A GAI AGCRF+AGYPITPS+EIAE MARELPKVGG ++QMEDEIAS Sbjct: 4 PEMMFLQGNEACALGAIKAGCRFFAGYPITPSTEIAEVMARELPKVGGVFVQMEDEIASA 63 Query: 92 AAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQG 151 AA+VGAS G+K MTATSGPGFSL+QE +GYA+MTETP V +V R GPSTG TK AQG Sbjct: 64 AAVVGASLAGVKSMTATSGPGFSLIQEVIGYAIMTETPCVFANVMRLGPSTGLPTKPAQG 123 Query: 152 DFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIR 211 D Q RWGTHGDH I+A+ P SV + + I AFN+AE RTPVV L D +LGH RE Sbjct: 124 DIMQTRWGTHGDHAIIALYPSSVAEVYRYIITAFNLAEEYRTPVVFLMDAMLGHMRESFY 183 Query: 212 IPDPDEVEIVYRKLPQN--EEEARLPFGDPHGDGVPPMPLFGHGYFT-HVTGSTHKENGL 268 P +E+ I+ R + EE+ +PF + P P+ G HV+G H E+G Sbjct: 184 PPKDEELFIIERLKDTSFGEEDLFVPFSESEYAEPTPFPMAEMGKTKFHVSGLVHDESGF 243 Query: 269 RDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAR 328 + + + +KL+RR+ KI + + YEEY T+DAEILVV++G+ AR ++ AV AR Sbjct: 244 -PLSSPDAAEKLIRRLTNKIRLHADEIAFYEEYETEDAEILVVAYGIVARSAMKAVKIAR 302 Query: 329 KEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILE-VQRFVNDDVLLKGV 387 ++ IKVGLF P T+ P P R R+L +KV I++ EMNLGQ E + +++ + Sbjct: 303 RDRIKVGLFKPITIWPAPVSRFRKLAEKVNTIVIAEMNLGQYAKELISSIDRRSKVIRTI 362 Query: 388 NKIGGVPLTVEEIL 401 NK+ G + EEIL Sbjct: 363 NKVNGELIKPEEIL 376 >pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain Cj0536 [similarity] - Campylobacter jejuni (strain NCTC 11168) >gi|6968004|emb|CAB75172.1| (AL139075) OORA subunit of 2-oxoglutarate:acceptor oxidoreductase [Campylobacter jejuni] Length = 374 Score = 282 bits (713), Expect = 6e-75 Identities = 148/367 (40%), Positives = 230/367 (62%), Gaps = 3/367 (0%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G+ +A AI GC+F+ GYPITPSSEIA ++ LP G ++QMEDEI+ I+ +GA+ Sbjct: 8 GNVLIAKAAIDCGCKFFGGYPITPSSEIAHELSHMLPANDGTFIQMEDEISGISVAIGAA 67 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 +G+K MTA+SGPG SL E +G A + E PLV+V+V R GPSTG T+ AQGD FQA+ Sbjct: 68 MSGVKSMTASSGPGISLKAEQIGLAFIAEIPLVIVNVMRGGPSTGLPTRVAQGDLFQAKA 127 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218 THGD +AI+P S+E+A+ ETIRAFN+AE+ TPV +L D +GH + +PD ++ Sbjct: 128 PTHGDFASIAIAPASLEEAYTETIRAFNLAEKYMTPVFLLMDETVGHMNGKAVLPDLKDI 187 Query: 219 EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHD 278 ++ RK + +++ P+ + P F GY HVTG H + G + Sbjct: 188 KVYNRKKFEGDKKDYKPYAAGENEPATLNPFF-TGYRYHVTGLHHGDIGF-PTEDGVIVK 245 Query: 279 KLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFV 338 K + R+ KI+ N+E YEEY DDAE L++++G +R + A+ + R++GIKVGLF Sbjct: 246 KNMERLIGKIKNNQEDICTYEEYMLDDAEFLIIAYGSVSRSAKEAIQRLREQGIKVGLFR 305 Query: 339 PKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVE 398 P T++P +++ E+ K + ++V E+N+GQ + E++R + + +++ G P+T Sbjct: 306 PITLYPVAEKKIAEVVSKFKKVMVSELNMGQYLEEIERVTSRRDFI-SLHRANGRPITPS 364 Query: 399 EILREIR 405 EI+ +++ Sbjct: 365 EIIAKVK 371 >gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Archaeoglobus fulgidus] >gi|6685587|sp|O29781|KORA_ARCFU 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7433685|pir||E69308 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain korA - Archaeoglobus fulgidus >gi|2650159|gb|AAB90768.1| (AE001072) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Archaeoglobus fulgidus] Length = 346 Score = 279 bits (706), Expect = 4e-74 Identities = 157/370 (42%), Positives = 224/370 (60%), Gaps = 31/370 (8%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96 + G+EA GAI AGC F+AGYPITPSSEIA MA LPK GG ++QMEDEIASI+A++G Sbjct: 6 IQGNEAAVRGAINAGCNFFAGYPITPSSEIAHGMAELLPKFGGVFIQMEDEIASISAVIG 65 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156 AS G MTATSGPGFSLMQE +GYA +TE+P+V+ +V R+GPSTG T +QGD QA Sbjct: 66 ASMAGAVAMTATSGPGFSLMQEGMGYAAITESPVVIFNVMRAGPSTGIPTAPSQGDAMQA 125 Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPD 216 R+G+HGD+PIV ++P SV+D ++ T+ AF +A R TPV+VL D I+GH RE + +P Sbjct: 126 RYGSHGDYPIVVLAPASVKDMYYLTVEAFKIAFRFSTPVIVLSDEIVGHMRESVALPPLG 185 Query: 217 EVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276 E+E Y K +N + R H TG H ENGL +E Sbjct: 186 EIE-SYEKRAKNLIDGRR---------------------RHRTGLVHTENGLPTTDLEE- 222 Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGL 336 ++KL+R + K + R + + + +L V++G S R + + ++G+ G+ Sbjct: 223 YEKLLRLLFAKFDDFRPMVR-----FEGEEGVLFVAYGSSYRLAKSSAKLLAEKGVSAGI 277 Query: 337 FVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLT 396 +++ PFP + +R KK ++VPEMN GQ++ EV+R V KGV+ G + L Sbjct: 278 LKLESLFPFPEDAVRRYSKKADLVVVPEMNAGQVVKEVERVCCCRV--KGVSYFGSLILP 335 Query: 397 VEEILREIRG 406 E+++ + G Sbjct: 336 -EKLVEIVEG 344 >pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Helicobacter pylori (strain 26695) >gi|2313707|gb|AAD07654.1| (AE000572) ferredoxin oxidoreductase, alpha subunit [Helicobacter pylori 26695] Length = 375 Score = 268 bits (677), Expect = 1e-70 Identities = 152/370 (41%), Positives = 224/370 (60%), Gaps = 7/370 (1%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G+E VA AI GCRF+ GYPITPSS+I M+ LPK GG+++QMEDEI+ I+ +GAS Sbjct: 8 GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 +G K MTA+SGPG SL E +GY+ M E PLV+ DV RSGPSTG T+ AQGD R Sbjct: 68 MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218 HGD VA++P ++E+A+ ET+RAFN+AE L TPV +L D +GH +++IPD +EV Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187 Query: 219 E--IVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276 + + RK +++ P+G + P F GY HV+G H G ++ Sbjct: 188 QKMTINRKEFLGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGF-PTEDAKI 245 Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG-IKVG 335 L+ R+ KIE +++ + EE + AEI+V+++G + A+ KE KVG Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVVIAYGSVSLAVKEALKDYHKESKQKVG 305 Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395 F PKT+ P P +R++E+G K ILV E+N GQ + E++R + V G + G + Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERAMQRKVHFLG--QANGRTI 363 Query: 396 TVEEILREIR 405 + ++I+ +++ Sbjct: 364 SPKQIIAKLK 373 >pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacter pylori (strain J99) >gi|4155084|gb|AAD06119.1| (AE001486) SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE [Helicobacter pylori J99] Length = 375 Score = 266 bits (673), Expect = 3e-70 Identities = 150/370 (40%), Positives = 223/370 (59%), Gaps = 7/370 (1%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G+E VA AI GCRF+ GYPITPSS+I M+ LPK GG+++QMEDEI+ I+ +GAS Sbjct: 8 GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 +G K MTA+SGPG SL E +GY+ M E PLV+ DV RSGPSTG T+ AQGD R Sbjct: 68 MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218 HGD VA++P ++E+A+ ET+RAFN+AE L TPV +L D +GH +++IPD +EV Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187 Query: 219 E--IVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276 + + RK +++ P+G + P F GY HV+G H G ++ Sbjct: 188 QKMTINRKEFAGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGF-PTEDAKI 245 Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG-IKVG 335 L+ R+ KIE +++ + EE + EI+++++G + A+ KE KVG Sbjct: 246 GGDLIDRLFHKIESKQDIINENEEMDLEGTEIVIIAYGSVSLAVKEALKDYNKESKQKVG 305 Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395 F PKT+ P P +R++E+G K ILV E+N GQ + E++R + V G + G + Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERVMQRKVHFFG--QANGRTI 363 Query: 396 TVEEILREIR 405 + ++I+ +++ Sbjct: 364 SPKQIIAKLK 373 >gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:acceptor oxidoreductase [Helicobacter pylori] Length = 371 Score = 257 bits (649), Expect = 2e-67 Identities = 144/340 (42%), Positives = 206/340 (60%), Gaps = 5/340 (1%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G+E VA AI GCRF+ GYPITPSS+I M+ LP GG+++QMEDEI+ I+ +GAS Sbjct: 8 GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPNCGGHFIQMEDEISGISVSLGAS 67 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 +G K MTA+SGPG SL E +GY+ M E PLV+ DV RSGPSTG T+ QGD R Sbjct: 68 MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVDQGDVNFLRH 127 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218 HGD VA++P S+E+A+ ET RAFN+AE L TPV +L D +GH +++IPD +EV Sbjct: 128 PIHGDFKAVALAPASLEEAYTETARAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187 Query: 219 E--IVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEV 276 + + RK +++ P+G + P F GY HV+G H G ++ Sbjct: 188 QKTTINRKEFVGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGF-PTEDAKI 245 Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE-GIKVG 335 L+ R+ KIE +++ + EE + AEI+++++G + A+ KE KVG Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVIIAYGSVSLAVKEALKDYHKESNQKVG 305 Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQ 375 F PKT+ P P +R++E+G K ILV E+N GQ + +++ Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLKKLK 345 >pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8) >gi|4982338|gb|AAD36824.1|AE001814_6 (AE001814) 2-oxoisovalerate oxidoreductase, beta subunit, putative [Thermotoga maritima] Length = 356 Score = 246 bits (621), Expect = 4e-64 Identities = 150/380 (39%), Positives = 209/380 (54%), Gaps = 46/380 (12%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96 M G+EA+A AI AGCR Y YPITP SEIAE MAR LP+VGG +LQ E EIA++ + G Sbjct: 9 MKGNEAIAESAIRAGCRLYFAYPITPQSEIAEYMARRLPEVGGVFLQTESEIATVNMVYG 68 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156 A+ TG +VMT+TS PGFSLMQE + Y E P V VDV R GP G + +QGD+FQA Sbjct: 69 AACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGN-IQPSQGDYFQA 127 Query: 157 -RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD- 214 + G HGD+ ++ ++P ++++A T AF++A+R R PV++L DG++G E + +P+ Sbjct: 128 VKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLADRYRNPVLILADGMIGQMMEPVELPEM 187 Query: 215 ------PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGL 268 PD + R E F + P+ L Sbjct: 188 RDLSTLPDHSDWALRGARNREPHRIAAF------NIDPVGL------------------- 222 Query: 269 RDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAR 328 +K+ +R+ K +++EEY D AE L+V +G R V R Sbjct: 223 ---------EKMNKRLQEKYRLIEASEQRWEEYRVDGAEYLMVGYGTMGRILKSVVDSLR 273 Query: 329 KEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVN 388 +EGI GLF P T+ PFP R++EL KKV+ I V EM+ GQM+ +VQ V V + Sbjct: 274 EEGIPAGLFRPVTLWPFPKRRLKELAKKVQLIFVVEMSSGQMVEDVQISVEGKVPVHFYG 333 Query: 389 KIGGVPLTVEEIL---REIR 405 ++GGV T EEIL +E+R Sbjct: 334 RMGGVVPTPEEILFAFKEVR 353 >dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Bacillus halodurans] Length = 579 Score = 204 bits (514), Expect = 1e-51 Identities = 125/374 (33%), Positives = 199/374 (52%), Gaps = 10/374 (2%) Query: 36 FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95 FM+G++A+ GA+ AG RF A YPITP+SEI E + ++LP+ GG +Q EDEIA+ + Sbjct: 199 FMIGNDAIGMGAVAAGSRFMAAYPITPASEIMEYLIKKLPEFGGAVIQTEDEIAACTMAI 258 Query: 96 GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155 GA++ G++ TA++GPG SLM E +G + MTETPLV+VD QR GPS G TK Q D Sbjct: 259 GANYAGVRSFTASAGPGLSLMAEAIGLSGMTETPLVIVDTQRGGPSIGLPTKQEQSDLMA 318 Query: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215 + THGD P V ++P +VE+AF++T+ AFN+AE + PV+++ D L ++ + D Sbjct: 319 MIYSTHGDIPKVVMAPSTVEEAFYDTVEAFNIAEEYQCPVILVTDLALSLGKQTVEPLDF 378 Query: 216 DEVEIVYRKLPQNEEEARLPFGDPH------GDGVPPMPLFGH-GYFTHVTGSTHKENGL 268 +VEI L ++ G+ + GV P L G HVTG H + G Sbjct: 379 SKVEIRRGSLQNEDQLTEQEKGEYYKRYELTETGVSPRVLPGQKNGIHHVTGVEHDQTGK 438 Query: 269 RDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYT--DDAEILVVSWGVSARPSLGAVLK 326 +++ +R+ RK+E E + + ++ ++LV+ + A+ + Sbjct: 439 PSESATNRIEQMEKRL-RKVEALPERFPTPVHIHAPHEEPDLLVIGINSTRGAIEEAIPR 497 Query: 327 ARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKG 386 + I+V + VHPFP ++ K + ++V E N + + + D ++ Sbjct: 498 LEADSIRVNHAHIRLVHPFPKHELQPYLTKAKKVVVVEHNATAQLASLIKMNCDVKAIEN 557 Query: 387 VNKIGGVPLTVEEI 400 V + G P EI Sbjct: 558 VLRYDGNPFLPGEI 571 >sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) Length = 352 Score = 202 bits (509), Expect = 5e-51 Identities = 134/371 (36%), Positives = 200/371 (53%), Gaps = 32/371 (8%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G+ AV GA++AGC Y GYPITP+SEI +R P VG ++Q E E A+I + GA+ Sbjct: 8 GNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAA 67 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ-AR 157 G +VMTA+SGPG SL QE + + E P V+VDV R+GP G QGD+ Q + Sbjct: 68 AAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGP-EQGDYNQIVK 126 Query: 158 WGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDE 217 G HG++ + ++P SV++ T+ AF +A++ R PVVVL D +LG E +R P+ + Sbjct: 127 GGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPE-EA 185 Query: 218 VEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVH 277 VE H ++ S + + + + Sbjct: 186 VE--------------------HRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQ 225 Query: 278 DKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLF 337 +K R IE+N +YEEY DDAEI++V++G+S+R + AV AR EGI VGL Sbjct: 226 EKYAR-----IEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLL 277 Query: 338 VPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTV 397 P T+ PFP +R+REL + EM+ GQM ++ R + ++ VN++GG + + Sbjct: 278 RPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDI-RMASGCRDVELVNRMGGNLIEL 336 Query: 398 EEILREIRGVA 408 ++L +IR VA Sbjct: 337 RDVLEKIREVA 347 >pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621790|gb|AAB85209.1| (AE000849) 2-oxoisovalerate oxidoreductase, beta subunit [Methanobacterium thermoautotrophicum] Length = 348 Score = 202 bits (509), Expect = 5e-51 Identities = 134/371 (36%), Positives = 200/371 (53%), Gaps = 32/371 (8%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G+ AV GA++AGC Y GYPITP+SEI +R P VG ++Q E E A+I + GA+ Sbjct: 4 GNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAA 63 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ-AR 157 G +VMTA+SGPG SL QE + + E P V+VDV R+GP G QGD+ Q + Sbjct: 64 AAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGP-EQGDYNQIVK 122 Query: 158 WGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDE 217 G HG++ + ++P SV++ T+ AF +A++ R PVVVL D +LG E +R P+ + Sbjct: 123 GGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPE-EA 181 Query: 218 VEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVH 277 VE H ++ S + + + + Sbjct: 182 VE--------------------HRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQ 221 Query: 278 DKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLF 337 +K R IE+N +YEEY DDAEI++V++G+S+R + AV AR EGI VGL Sbjct: 222 EKYAR-----IEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLL 273 Query: 338 VPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTV 397 P T+ PFP +R+REL + EM+ GQM ++ R + ++ VN++GG + + Sbjct: 274 RPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDI-RMASGCRDVELVNRMGGNLIEL 332 Query: 398 EEILREIRGVA 408 ++L +IR VA Sbjct: 333 RDVLEKIREVA 343 >gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, subunit alpha; PorA [Halobacterium sp. NRC-1] Length = 582 Score = 200 bits (504), Expect = 2e-50 Identities = 140/381 (36%), Positives = 199/381 (51%), Gaps = 22/381 (5%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 GDEA+ GAI AGCRFYAGYPITP++++ E + + + GG+ +Q EDE+A+I +GA+ Sbjct: 204 GDEAIGMGAIAAGCRFYAGYPITPATDVMEYLTGRIEQFGGHVVQAEDELAAINLALGAA 263 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 G + MTATSGPG LM E G +ETPLV+ +V RSGPSTG TK QGD Sbjct: 264 RAGARSMTATSGPGIDLMSETFGLVATSETPLVIANVMRSGPSTGMPTKQEQGDLNMMLK 323 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIP---DP 215 G HG+ P ++P SV + F +T+ AFN+AE+ + PV V D + T E+ P D Sbjct: 324 GGHGEIPRFVVAPTSVAECFHKTVEAFNLAEKYQLPVYVTADLSMAVT-ERTYPPEEFDM 382 Query: 216 DEVEIVYRKLP--------QNEEEARLPFGDPHGDGVPPMPLFGHGYFTHV-TGSTHKEN 266 D VEI KL QN+ E P D DG+ P + G H+ TG H E Sbjct: 383 DAVEIERGKLVDEDEISAWQNDTEQFRPHADT-ADGISPRAVPGTEGGVHMSTGLEHDEL 441 Query: 267 GLRDVYTQEVHDKLVRRIHRKIEQNREVYE-KYEEYYTDDAEILVVSWGVSARPSLGAVL 325 G R T D++ +R +RK++ RE + Y E+ DA+ LVVSWG S ++ L Sbjct: 442 GRRTEDTDVRVDQVDKR-YRKVDTAREREQFDYREFGDSDADNLVVSWG-SNEGTIVEAL 499 Query: 326 KARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVL-- 383 + + V + +P + + + ++V E N +V + DVL Sbjct: 500 EYLDGDDDPDIRVVSVPYIYPRPDLTDEVEAADDVVVVEANATGQFADV---IEHDVLER 556 Query: 384 LKGVNKIGGVPLTVEEILREI 404 + +N GV +E+ EI Sbjct: 557 VTRINNYTGVDFKADELAAEI 577 >pir||F70864 probable oxidoreductase alpha subunit - Mycobacterium tuberculosis (strain H37RV) >gi|2791495|emb|CAA16032.1| (AL021246) hypothetical protein Rv2455c [Mycobacterium tuberculosis] Length = 653 Score = 190 bits (477), Expect = 3e-47 Identities = 131/381 (34%), Positives = 193/381 (50%), Gaps = 13/381 (3%) Query: 32 PGNYFMM-GDEAVAYGAIFAGCR-----FYAGYPITPSSEIAETMARELPKVGGYYLQME 85 PG Y + G+ A+AYG + AG YPITP+S+I +++ Q E Sbjct: 248 PGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYPITPASDILHELSKH-KNFNVVTFQAE 306 Query: 86 DEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQA 145 DEI I A +GA++ G +T+TSGPG SL E LG VMTE PL+++DVQR GPSTG Sbjct: 307 DEIGGICAALGAAYGGALGVTSTSGPGISLKSEALGLGVMTELPLLVIDVQRGGPSTGLP 366 Query: 146 TKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGH 205 TK Q D QA +G +G+ P+ ++P S D F + A +A TPV++L DG + + Sbjct: 367 TKTEQADLLQALYGRNGESPVAVLAPRSPADCFETALEAVRIAVSYHTPVILLSDGAIAN 426 Query: 206 TREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKE 265 E RIPD + + + + E + P+ + G H G Sbjct: 427 GSEPWRIPDVNALPPIKHTFAKPGEPFQ-PYARDRETLARQFAIPGTPGLEHRIGGLEAA 485 Query: 266 NGLRDV-YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAV 324 NG D+ Y HD +VR KI+ V + + T DAE+L++ WG S P A Sbjct: 486 NGSGDISYEPTNHDLMVRLRQAKID-GIHVPDLEVDDPTGDAELLLIGWGSSYGPIGEAC 544 Query: 325 LKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLL 384 +AR+ G KV + ++PFP + E+ ++ ++ PE+NLGQ+ ++ DV Sbjct: 545 RRARRRGTKVAHAHLRYLNPFPA-NLGEVLRRYPKVVAPELNLGQLAQVLRGKYLVDV-- 601 Query: 385 KGVNKIGGVPLTVEEILREIR 405 + V K+ GV +EI R IR Sbjct: 602 QSVTKVKGVSFLADEIGRFIR 622 >emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit [Streptomyces coelicolor] Length = 630 Score = 186 bits (468), Expect = 3e-46 Identities = 130/387 (33%), Positives = 200/387 (51%), Gaps = 24/387 (6%) Query: 30 YKPGNYF-MMGDEAVAYGAIFAGCR-----FYAGYPITPSSEIAETMARELPKVGGYYLQ 83 + PG Y + G+ A+AYG I A R F YPITP+S+I +++ G Q Sbjct: 242 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKH-KNFGVRTFQ 300 Query: 84 MEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTG 143 EDEIA I A +GA++ G +T TSGPG +L E +G AV E PL++VD+QR GPSTG Sbjct: 301 AEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPSTG 360 Query: 144 QATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGIL 203 TK Q D QA +G +G+ P+ ++P + D F + A +A RTPV +L DG L Sbjct: 361 LPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGYL 420 Query: 204 GHTREQIRIPDPDEVEIVYRKLPQ-------NEEEARLPF-GDPHGDGVPPMPLFGHGYF 255 + E RIP+PDE+ + + Q + E P+ DPH P + G Sbjct: 421 ANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPGL 479 Query: 256 THVTGSTHKENGLRDV-YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWG 314 H G K++G ++ Y HD +VR KI+ ++ D A LV+ WG Sbjct: 480 EHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKIDGITVPDLAVDD--PDGARTLVLGWG 537 Query: 315 VSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEV 374 + P AV + RKE ++ + ++PFP + + ++ ++VPEMNLGQ+ + Sbjct: 538 STYGPITAAVRRIRKEVGQIAQAHLRHLNPFPA-NLGAVLERYDKVVVPEMNLGQLATLI 596 Query: 375 Q-RFVNDDVLLKGVNKIGGVPLTVEEI 400 + +++ D + N++ G+P E++ Sbjct: 597 RAKYLVD---AQSYNQVNGMPFKAEQL 620 >emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces coelicolor] Length = 645 Score = 186 bits (468), Expect = 3e-46 Identities = 130/387 (33%), Positives = 200/387 (51%), Gaps = 24/387 (6%) Query: 30 YKPGNYF-MMGDEAVAYGAIFAGCR-----FYAGYPITPSSEIAETMARELPKVGGYYLQ 83 + PG Y + G+ A+AYG I A R F YPITP+S+I +++ G Q Sbjct: 257 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKH-KNFGVRTFQ 315 Query: 84 MEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTG 143 EDEIA I A +GA++ G +T TSGPG +L E +G AV E PL++VD+QR GPSTG Sbjct: 316 AEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPSTG 375 Query: 144 QATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGIL 203 TK Q D QA +G +G+ P+ ++P + D F + A +A RTPV +L DG L Sbjct: 376 LPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGYL 435 Query: 204 GHTREQIRIPDPDEVEIVYRKLPQ-------NEEEARLPF-GDPHGDGVPPMPLFGHGYF 255 + E RIP+PDE+ + + Q + E P+ DPH P + G Sbjct: 436 ANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPGL 494 Query: 256 THVTGSTHKENGLRDV-YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWG 314 H G K++G ++ Y HD +VR KI+ ++ D A LV+ WG Sbjct: 495 EHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKIDGITVPDLAVDD--PDGARTLVLGWG 552 Query: 315 VSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEV 374 + P AV + RKE ++ + ++PFP + + ++ ++VPEMNLGQ+ + Sbjct: 553 STYGPITAAVRRIRKEVGQIAQAHLRHLNPFPA-NLGAVLERYDKVVVPEMNLGQLATLI 611 Query: 375 Q-RFVNDDVLLKGVNKIGGVPLTVEEI 400 + +++ D + N++ G+P E++ Sbjct: 612 RAKYLVD---AQSYNQVNGMPFKAEQL 635 >pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha chain APE2126 - Aeropyrum pernix (strain K1) >gi|5105825|dbj|BAA81137.1| (AP000063) 644aa long hypothetical 2-oxoacid--ferredoxin oxidoreductase alpha chain [Aeropyrum pernix] Length = 644 Score = 180 bits (452), Expect = 3e-44 Identities = 123/359 (34%), Positives = 192/359 (53%), Gaps = 28/359 (7%) Query: 31 KPGNYFMM-GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMAR-ELPKVGGY------YL 82 K G Y + G++ VA G + G R+ A YPITP+S+ + + E K+ G L Sbjct: 243 KSGEYVVASGNDVVAMGKVVGGVRYQAYYPITPASDESVLLEEFEGLKIDGESLGSIAIL 302 Query: 83 QMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPST 142 Q EDEIA++++++GA+ TG + TATSGPGFSLM E LG+A + P+V+ QR GPST Sbjct: 303 QTEDEIAAVSSVIGAALTGARASTATSGPGFSLMVEALGWAGKNDVPMVITYYQRGGPST 362 Query: 143 GQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGI 202 G T+G+Q D + + +HG+ P + +S +AF++ I A+N+AER + PV+ L D Sbjct: 363 GLPTRGSQSDLLFSLFASHGEFPRIILSSGDHLEAFYDAIEAYNLAERFQMPVIHLLDKF 422 Query: 203 LGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGD----PHGDGVPPMPLFGHGYFTHV 258 L + + PD + K+ + + + P G P + P+ G G T Sbjct: 423 LANMVASVPFPDWKAI-----KIDRGKTLFKAPTGPFKRFPRDQPLADRPVLGSGAITWY 477 Query: 259 TGSTHKENGLRDVYTQEVHDKLV--RRIHRKIE-QNREVYEKYE-EYYTD-DAEILVVSW 313 TG + E G D ++ ++LV R +K+E +RE+ E + +YY D DAE+L+V W Sbjct: 478 TGDENDEYGHID---EDPVNRLVMYERRWKKMEIADREIPEDFRVKYYGDEDAEVLLVGW 534 Query: 314 GVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKV---RAILVPEMNLGQ 369 G P+L A+ + R+ G+ + + P P R+ E+ + R I V LGQ Sbjct: 535 GSVKIPALEAIERLREMGVNAAYLHLRMLSPLPKRRVSEVLSRFDADRVIAVEANYLGQ 593 >pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validated] - Halobacterium salinarum >gi|43498|emb|CAA45825.1| (X64521) pyruvate synthase [Halobacterium halobium] Length = 628 Score = 176 bits (442), Expect = 4e-43 Identities = 129/398 (32%), Positives = 191/398 (47%), Gaps = 45/398 (11%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96 M G A+AYGAI AGCRF +GYP+TP ++ M + LP +GG Q+EDEIA+ A VG Sbjct: 223 MSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVEDEIAAAAMAVG 282 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156 AS G K M+ +SG GF+LM E LG A MTETPLVL++ QR+GPSTG TK Q D Sbjct: 283 ASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMPTKPEQADLEHV 342 Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFD---------------- 200 + + GD VA P ++ + +T AF +A + PV++L+D Sbjct: 343 LYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSGEYRNVDASFFD 402 Query: 201 ----GILGHTREQIRIPD-PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYF 255 LG T + +IPD P + Y + + E DGV P + G Sbjct: 403 REPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVE-----------DGVSPRTIPGQSGG 451 Query: 256 THV-TGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE------YYTDDAEI 308 ++ +G+ H NG + E D V ++ R++++ + + +E Y +DA+I Sbjct: 452 RYLASGNEHWPNG----HISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADI 507 Query: 309 LVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLG 368 +++WG AV + +G V + PFP R V +V EM+ Sbjct: 508 GLIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSST 567 Query: 369 QMILE-VQRFVND-DVLLKGVNKIGGVPLTVEEILREI 404 + +Q+ V D L + K G P EI+ + Sbjct: 568 KQFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 605 >gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin oxidoreductase (alpha); KorA [Halobacterium sp. NRC-1] Length = 640 Score = 176 bits (442), Expect = 4e-43 Identities = 129/398 (32%), Positives = 191/398 (47%), Gaps = 45/398 (11%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVG 96 M G A+AYGAI AGCRF +GYP+TP ++ M + LP +GG Q+EDEIA+ A VG Sbjct: 235 MSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVEDEIAAAAMAVG 294 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156 AS G K M+ +SG GF+LM E LG A MTETPLVL++ QR+GPSTG TK Q D Sbjct: 295 ASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMPTKPEQADLEHV 354 Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFD---------------- 200 + + GD VA P ++ + +T AF +A + PV++L+D Sbjct: 355 LYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSGEYRNVDASFFD 414 Query: 201 ----GILGHTREQIRIPD-PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYF 255 LG T + +IPD P + Y + + E DGV P + G Sbjct: 415 REPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVE-----------DGVSPRTIPGQSGG 463 Query: 256 THV-TGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEE------YYTDDAEI 308 ++ +G+ H NG + E D V ++ R++++ + + +E Y +DA+I Sbjct: 464 RYLASGNEHWPNG----HISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADI 519 Query: 309 LVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLG 368 +++WG AV + +G V + PFP R V +V EM+ Sbjct: 520 GLIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSST 579 Query: 369 QMILE-VQRFVND-DVLLKGVNKIGGVPLTVEEILREI 404 + +Q+ V D L + K G P EI+ + Sbjct: 580 KQFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 617 >emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidoreductase, alpha chain [Thermoplasma acidophilum] Length = 629 Score = 176 bits (442), Expect = 4e-43 Identities = 118/397 (29%), Positives = 193/397 (47%), Gaps = 18/397 (4%) Query: 26 LRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETM------------ARE 73 L L P + G++A A G + G RF YPITP+S+ + T+ A Sbjct: 222 LPALPTPRKLLLTGNDASALGKLLGGLRFQTYYPITPASDESTTIEEHQNIKWLDKEAAN 281 Query: 74 LPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLV 133 L K G +Q EDE++++ +G + TG++ TATSGPGFSLM E L +A M E PLV+ Sbjct: 282 LKKGGVVIVQTEDELSAVNMAIGGALTGVRSATATSGPGFSLMAEGLSFAGMDEVPLVVT 341 Query: 134 DVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRT 193 +R GPSTG T+ Q D A HG++P + S +V++ ++ +A N A + + Sbjct: 342 FYERGGPSTGLPTRNGQSDLLFALNAGHGEYPRIVFSSGTVDECIYDAAKALNYAAKYQM 401 Query: 194 PVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHG 253 PV+ L D L +T + I D D ++I KL + ++ + + +GV P G Sbjct: 402 PVIHLIDKNLANTLDLISKVDLDRIKIETVKLAKEGDDVK-RYDLNTDNGVSPYTTMGRN 460 Query: 254 YFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE-QNRE--VYEKYEEYYTDDAEILV 310 F +TG H E G ++ D+++ + +K+E +RE + EK +A+I Sbjct: 461 IF-WMTGDEHDELG-HVTEDSDIRDRMMEKRFKKLETADREIPIDEKAVLIGEKEADITF 518 Query: 311 VSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQM 370 V+WG P L + ++EGI L K PFP E ++ + ++ E N Sbjct: 519 VTWGSQKGPILDVIEDLKEEGISANLLYLKMFSPFPTEFVKNVLSSANLVIDVESNYTAQ 578 Query: 371 ILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGV 407 ++ + + + K G +T +EIL+ + + Sbjct: 579 AAQMIKLYTGIDIKNKILKYNGRHMTEDEILKSAKEI 615 >emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidoreductase, alpha subunit [Thermoplasma acidophilum] Length = 588 Score = 168 bits (420), Expect = 1e-40 Identities = 116/371 (31%), Positives = 184/371 (49%), Gaps = 16/371 (4%) Query: 26 LRKLYKPGN--YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQ 83 L K +K G Y + G AVA GA+ G + Y YP+TP+S +A+ K G + Sbjct: 195 LGKKFKFGKKKYMISGGMAVALGAVAGGLKMYVAYPMTPASSALHFLAQHAKKYGVFVKI 254 Query: 84 MEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTG 143 EDEI++I ++GA++ G++ MT +SG GF+LM E +G + MTE PLV+ + QR GPSTG Sbjct: 255 PEDEISAINTVIGANYAGVRAMTGSSGGGFALMTEAVGLSGMTEVPLVIYEAQRPGPSTG 314 Query: 144 QATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGIL 203 TK QGD Q + GD P + +P +E+AF+ T A N+AE+ +TPV V+ D L Sbjct: 315 LPTKTEQGDLNQVLGASQGDFPRIVFAPGDIEEAFYLTREAMNIAEKYQTPVFVMSDLYL 374 Query: 204 GHTREQIRIPDPD-EVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGH-GYFTHVTGS 261 + I D + ++ R ++ R + G+ P + G G + Sbjct: 375 AEHYDTIDSFDLNFNIDHGLRAKDNEQDYKRYLITE---TGISPRAIPGQPGNMHNEDSD 431 Query: 262 THKENGLRDVYTQEVHD-----KLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVS 316 H E G DV + V + K++++ RK++ E + Y DAE +++ WG + Sbjct: 432 EHNEYG--DVVSDAVTNPQDRIKMMQKRMRKLDTYIEEMKPTPTYRIQDAEYVIIQWGST 489 Query: 317 ARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQM--ILEV 374 A+ R +GIK+G K V P + L + + + V GQ+ + Sbjct: 490 KGAVEEAIDILRAKGIKIGAIEVKNVFPLNPDIGTLLKNRKKILAVENNYSGQLSKYIAA 549 Query: 375 QRFVNDDVLLK 385 Q V +++ K Sbjct: 550 QFLVKPELITK 560 >pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha chain APE1473 - Aeropyrum pernix (strain K1) >gi|5105157|dbj|BAA80471.1| (AP000061) 616aa long hypothetical 2-oxoacid--ferredoxin oxidoreductase , alpha chain [Aeropyrum pernix] Length = 616 Score = 167 bits (419), Expect = 2e-40 Identities = 127/393 (32%), Positives = 192/393 (48%), Gaps = 32/393 (8%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSE------------IAETMAREL--PKVGGYYLQM 84 G++ VA G I G YPITPSS+ I +A +L K+ +QM Sbjct: 218 GNDLVAMGKIVGGLGVITYYPITPSSDEALYVEKHSYISIDGPLAEKLGYDKIAVAIVQM 277 Query: 85 EDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQ 144 EDE+ASI A++GA+ G + T TSGPGFSLM E + AV E P+V+ R+GPSTG Sbjct: 278 EDELASINAVLGAAAAGARASTTTSGPGFSLMNEAVSLAVEAEIPVVVTLWMRAGPSTGM 337 Query: 145 ATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILG 204 T+ Q D + + HGD P + ++ +AF++ I+AFN AE +TPV+ L D L Sbjct: 338 PTRTGQQDLLHSIFSGHGDAPKIVLASGDHVEAFYDAIKAFNWAEEFQTPVIHLLDKYLA 397 Query: 205 HT-----REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVT 259 + RE + DP +V I KL N + + DG+ P G +T Sbjct: 398 SSMVSLAREDL---DPSKVPITRGKLLDNPPADYRRY-EVVEDGISPRARLGSATMV-IT 452 Query: 260 GSTHKENG--LRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSA 317 G H E G D +E+ R + IE+ EK + +A + +VS+G + Sbjct: 453 GLEHDEYGYATEDPVMREIMMFKRERKFKVIEERIPDEEKAVLHGDSEASVALVSFGSTK 512 Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN-LGQ--MILEV 374 +P L A+ R EG++ + ++PFPG + E+ + V +++ E N LGQ M+L Sbjct: 513 QPILEALEMLRDEGVRARFAQVRLLYPFPGRLVEEMLEGVEKVIMVEQNLLGQLAMLLRA 572 Query: 375 QRFVNDDVLLKGVNKIGGVPLTVEEILREIRGV 407 + D + KI G PL E+ ++ + Sbjct: 573 HTSIKPD---SSIVKINGRPLYSFEVAGAVKRI 602 >gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain [Sulfolobus solfataricus] Length = 632 Score = 162 bits (407), Expect = 5e-39 Identities = 120/385 (31%), Positives = 182/385 (47%), Gaps = 17/385 (4%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSS------EIAETMARELPKVGG------YYLQMED 86 G+ A A G I+ G RF + YPITP+S E +T+ PK G +Q ED Sbjct: 235 GNTAAAIGKIYGGLRFQSYYPITPASDESVFIEAHQTVFTVDPKTGEKRKSTIVVVQAED 294 Query: 87 EIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQAT 146 E+A+I GA+ TG++ TATSGPGFSLM E +G+A M E P+V+ R GPSTGQ T Sbjct: 295 ELAAINMASGAALTGVRAATATSGPGFSLMVEGMGWAGMNEVPVVITYYIRGGPSTGQPT 354 Query: 147 KGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHT 206 + +Q D A HG+ P + I+ +AF + A N+A++ +TPV+ L D L ++ Sbjct: 355 RTSQADLMFALNAGHGEFPRIVIASGDHVEAFHDGTWALNLAQKYQTPVIHLVDKALANS 414 Query: 207 REQI--RIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHK 264 I + + + I K+ N L + DG+ P G H TG H Sbjct: 415 YSIIPKKTLGMENIRIEKGKIVINTNTPELKRFEITEDGISPFAPLGTAR-VHYTGDEHD 473 Query: 265 ENGLRDVYTQEVHDKLVRRIHRKIEQNREVYE--KYEEYYTDDAEILVVSWGVSARPSLG 322 E G ++ +RI + + ++E+ E + Y D+++ +++WG L Sbjct: 474 EYGFIAEASENREKMYEKRIKKLMTADKEIPEESRVNVYGNTDSKVAIITWGSPKGAILD 533 Query: 323 AVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDV 382 A+ + EGIK L + PFP MR+L I+ E N EV + Sbjct: 534 AMEELENEGIKPMLIQIRMFSPFPKNLMRKLLNGKEFIIDVESNYFGQAGEVLKLNTGIE 593 Query: 383 LLKGVNKIGGVPLTVEEILREIRGV 407 + K G P+ +E+ I+ V Sbjct: 594 PTHYILKWNGRPMMRDEVKEGIKAV 618 >pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit - Thermotoga maritima (strain MSB8) >gi|4981713|gb|AAD36240.1|AE001773_9 (AE001773) 2-oxoacid ferredoxin oxidoreductase, alpha subunit [Thermotoga maritima] Length = 558 Score = 153 bits (382), Expect = 4e-36 Identities = 115/372 (30%), Positives = 184/372 (48%), Gaps = 14/372 (3%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G EAV GAI GC F + YP++PS+ + +A+ G Q EDEIA++ ++GA Sbjct: 197 GAEAVGLGAIAGGCNFVSSYPMSPSTSVLVFLAQHKNDFGIVVEQAEDEIAAMNMIIGAW 256 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 + G + + TSG GF+LM+E L A M E+P V+ QR GP+TG T+ QGD A + Sbjct: 257 YAGARGLVTTSGGGFALMEEALSLAGMIESPAVIHLAQRPGPATGLPTRTEQGDLNLALY 316 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218 HGD P V +P +VE+AF+ T +AFNVA++ + PV VL D L + + D +E+ Sbjct: 317 AGHGDFPRVIYAPGNVEEAFYLTQKAFNVADKYQVPVFVLTDQYLVDSYYNLPGFDLNEL 376 Query: 219 EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGY-FTHVTGSTHKENG-LRDVYTQEV 276 ++ + + R + DG+ P + G+G V H E G + + + V Sbjct: 377 KVEKHFIKTTRDYIRYAITE---DGISPRGIPGYGEGLVRVDSDEHDEFGHITEDFNTRV 433 Query: 277 HDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIK-VG 335 ++V + RK E ++ K + ++ +L+V+WG + P +K EG+ V Sbjct: 434 --RMVNKRLRKGETLKKEIVKPKLIGDENYRVLLVAWGSTLEP-----IKEAIEGLDGVA 486 Query: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395 L V P E + +K ++ E N + R V + + K G+ Sbjct: 487 LLHFSQVWPI-DESVATYFEKAEKVVAVEGNATGQFANLIRQVTGFHIKDRILKYNGLQF 545 Query: 396 TVEEILREIRGV 407 +VEE+ +I V Sbjct: 546 SVEELKEKIAEV 557 >pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621610|gb|AAB85042.1| (AE000836) 2-oxoacid:ferredoxin oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 512 Score = 143 bits (357), Expect = 4e-33 Identities = 113/365 (30%), Positives = 173/365 (46%), Gaps = 17/365 (4%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G EAV G I GCRF + YP+TPS+ + ++ + + Q EDEIA+I +GAS Sbjct: 153 GTEAVGIGCIAGGCRFMSSYPMTPSTPLQVFISENAAEFDMVFEQAEDEIAAINMCLGAS 212 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 + G + + ATSG GF+LM+E +G A M ETP+V+ QR GP+ G T+ AQ D A + Sbjct: 213 YAGARSLVATSGSGFALMEEAVGLAGMIETPVVIYIGQRPGPAVGLPTRTAQEDLNLALY 272 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDPDEV 218 G+ P ++P +EDA AFN+A+R + PV +L D L + P E Sbjct: 273 AGPGEFPRAILAPGKLEDAPEIAAHAFNLADRYQIPVFLLSDQYLADLYYDLPSPQIGE- 331 Query: 219 EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFT-HVTGSTHKENGLRDVYTQEVH 277 E Y E R F DG+ P + G+G T V H E GL +V Sbjct: 332 EPSYHITRTWEGYRRFEF---TADGISPRGIPGYGSGTVRVDSDEHDEEGL-ITEDLDVR 387 Query: 278 DKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLF 337 ++V + + ++E ++ K E Y D ++ WG + A+ G V + Sbjct: 388 RRMVEKRNLRLEMLKDDTLKPEVY--GDNSSALICWGSTYWLVREAI---ESSGADVSMV 442 Query: 338 VPKTVHPFPGERMRELGKKVRAILVPEMNLGQM--ILEVQRFVNDDVLLKGVNKIGGVPL 395 V+P P + + L R +V GQ +L+++ F D+ + G+P Sbjct: 443 HFSQVYPLPHDTLELLESFDRTAVVENNYRGQFADLLKLEGFEADE----RFRRYDGMPF 498 Query: 396 TVEEI 400 +VE + Sbjct: 499 SVEGV 503 >pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7) >gi|1565183|dbj|BAA10898.1| (D64024) 2-oxoacid:ferredoxin oxidoreductase subunit alpha [Sulfolobus sp. 7] Length = 632 Score = 141 bits (351), Expect = 2e-32 Identities = 121/403 (30%), Positives = 197/403 (48%), Gaps = 38/403 (9%) Query: 19 EPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSS------EIAETMAR 72 +P KE R +++ G+ AVA G I+ G RF + YPITP+S E + + Sbjct: 221 KPSSKERRR-------FWLDGNTAVAIGKIYGGVRFQSYYPITPASDESVYIEAHQDVLM 273 Query: 73 ELPKVGG------YYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMT 126 E P G +Q EDE+A+I +GA+ TG++ TATSGPGFSLM E LG+A M Sbjct: 274 EDPITGDKKKGTIVVVQAEDELAAINMAIGAALTGVRAATATSGPGFSLMVEGLGWAGMN 333 Query: 127 ETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFN 186 E P+V+ R GPSTG T+ AQ D + HG+ P + ++ +AF + I A N Sbjct: 334 EVPVVITYYIRGGPSTGLPTRTAQSDLIFPIFAGHGEFPKIVLASGDHAEAFKDAIWALN 393 Query: 187 VAERLRTPVVVLFDGILGHTREQIRIP--DPDEVEIVYRKLPQNEEEA--RLPFGDPHGD 242 +AE+ +TPV+ L + L ++ I + D+++ K+ ++ + + R F + D Sbjct: 394 LAEKYQTPVIHLVEKTLANSYSTIPYEELELDKLKAERGKIVESGDISYKRFKFTE---D 450 Query: 243 GVPPMPLFGHGYFTHVTGSTHKENG--LRDVYTQE-VHDKLVRRIHRKIEQNREVYEKYE 299 G+ P G + TG H E G DV + +++K ++++ ++ E Sbjct: 451 GISPRAFLGKATM-YYTGDEHNEEGHISEDVVNRTMMYEKRMKKL--EVADKEIPEESRV 507 Query: 300 EYYTD-DAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVR 358 + Y D ++ L+++WG S L +L+ + L + PFP + +L + Sbjct: 508 KIYGDLNSRNLIITWG-SPTGVLRDILE--ESNFDFTLLQIRMFSPFPKNLVSKLMEGRD 564 Query: 359 AILVPEMN-LGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEI 400 I+ E N L Q L V+ + DV + K G P +E+ Sbjct: 565 KIITVEGNYLAQTSLLVKMYTGKDV-TNSILKWNGRPFLRDEL 606 >emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma and alpha subunit in fusion) [Thermus thermophilus] Length = 617 Score = 138 bits (343), Expect = 2e-31 Identities = 127/412 (30%), Positives = 188/412 (44%), Gaps = 27/412 (6%) Query: 9 KVVGMIIRGDEPEQKELLRKLYK-PGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIA 67 KV + R + P L L PG ++ G +A A G + G RF YPI+P+++ + Sbjct: 205 KVAEAVYREEAPRLPFRLEVLGPAPGRIYLTGAQAAALGKLAGGLRFQTYYPISPATDES 264 Query: 68 ETMARE--LPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVM 125 + LP +Q EDEIA++ VGA+ G K TATSGPGFSLM E LG+A M Sbjct: 265 VFLEAHTHLPGADVAVVQTEDEIAAVNMAVGAALAGAKAATATSGPGFSLMAEGLGFAGM 324 Query: 126 TETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAF 185 E PLV+ QR T+ QGD A G HG++P + ++ + DAF + +A Sbjct: 325 IEAPLVVTLYQRGRAQHRLPTRTEQGDLMFAIRGGHGEYPRLVLASGDILDAFLDAQKAL 384 Query: 186 NVAERLRTPVVVLFDGILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGD-----PH 240 A R +T VV L D L + + P E V + R FG P Sbjct: 385 AWAWRYQTVVVHLLDKFLASLAQSL----PKEALKVLSLDGEKRLSPREGFGPYQRYAPG 440 Query: 241 GDGVPP-MPLFGHGYFTHVTGSTHKENG--LRDVYTQEVHDKLVRRIHRKIEQNREVYEK 297 DG+ P +P+ G F +T H G DV +E+ ++ +R+ + +E+ Sbjct: 441 EDGLSPFIPIGTPGGFYWMTSDEHDPLGHITEDVELREL--QMEKRMEKLELARKEI--P 496 Query: 298 YEEYYT--DDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGK 355 E+ YT D E+LV+ WG G +L+A VG + + PFP R+ L + Sbjct: 497 LEDQYTLFRDGEVLVLGWGTVK----GTLLEALDHLEGVGYLHLRLLWPFP--RIAPLLE 550 Query: 356 KVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPLTVEEILREIRGV 407 + V GQ+ VQ+ V + V G P +EE + ++ V Sbjct: 551 GKTLVTVEHNYSGQLADLVQQETLKRVHHRVVKYNGRAPSPLEEAVEALKVV 602 >gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA) [Archaeoglobus fulgidus] >gi|7433693|pir||E69343 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain orA - Archaeoglobus fulgidus >gi|2649863|gb|AAB90491.1| (AE001053) 2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA) [Archaeoglobus fulgidus] Length = 532 Score = 123 bits (306), Expect = 3e-27 Identities = 97/314 (30%), Positives = 151/314 (47%), Gaps = 29/314 (9%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMVGAS 98 G A+A G + AG +FY YP+TP+S I +A + V LQ E+EIA+I +G++ Sbjct: 184 GARAIAEGMLAAGLKFYYAYPMTPASPILHILAADSRCVA---LQPENEIAAIMMAIGSA 240 Query: 99 WTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARW 158 + G + TSG GF+LM E++ A M E P++++ QRSGPSTG AT AQ D + A Sbjct: 241 FGGERAAVGTSGGGFALMSESISLAGMAEVPVLIILAQRSGPSTGMATYTAQQDLYFALN 300 Query: 159 GTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPD--PD 216 HG+ P++ SP+++ED++ N+A + +TP ++L + + + ++ Sbjct: 301 PAHGEFPLIVASPITIEDSYRLAGELLNLAWQFQTPAILLTEKHITESLATAKLEGVVKR 360 Query: 217 EVEIVYRKLPQNEEEARLPFG-DPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275 EVEI K + A G P+ PP + H E G E Sbjct: 361 EVEIFREKGELFKRYAITESGISPY--AAPPA-------IFKANSNEHDEYGFA-TDDAE 410 Query: 276 VHDKLVRRIHRKIEQNREVYEKYEEY-YTDDAEILVVSWGVSARPSLGAVLKARKE-GIK 333 K+ + RK E+ R V Y + + +V+WG + GAV + +E G Sbjct: 411 TATKMYAKRMRKEEEIRRVVANLNPYVVVKNGKDWIVTWG----SNFGAVKEVAEELGFS 466 Query: 334 VG-------LFVPK 340 V LF+PK Sbjct: 467 VAAIRYMRPLFLPK 480 >pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain PAB1472 [similarity] - Pyrococcus abyssi (strain Orsay) >gi|5458784|emb|CAB50271.1| (AJ248287) KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-) (VOR) [Pyrococcus abyssi] Length = 395 Score = 113 bits (280), Expect = 4e-24 Identities = 98/349 (28%), Positives = 155/349 (44%), Gaps = 39/349 (11%) Query: 30 YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87 YKP + G+ A AY + A + A YPITP + I E +A + + Y+ +E E Sbjct: 4 YKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 63 Query: 88 IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147 +++AA +GAS TG +V TATS G +LM E L +A P+V+VDV R+ + + Sbjct: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRA-MAPPWSVW 122 Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-ILGHT 206 Q D R D + + ++ + + AF VAE + P +V+ IL HT Sbjct: 123 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHT 177 Query: 207 REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTH-------VT 259 E + +PQ + LP P PL+ F + T Sbjct: 178 YE------------IVNMIPQELVDEFLP---------PRKPLYSLADFENPIAVGALAT 216 Query: 260 GSTHKENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSA 317 + + E + E K+++ + R+ + R+ E E+ Y DDA+ + + G Sbjct: 217 PADYYEFRYKLARAHEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLM 276 Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366 AV RK+G KVG + PFP E + E+ + V+ I V + N Sbjct: 277 GTVKEAVELLRKQGYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325 >sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280154|pir||T45085 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain vorA - Pyrococcus furiosus >gi|1197360|emb|CAA59502.1| (X85250) 2-ketovalerate ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus] Length = 394 Score = 109 bits (269), Expect = 7e-23 Identities = 96/349 (27%), Positives = 153/349 (43%), Gaps = 39/349 (11%) Query: 30 YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87 YKP + G+ A AY A+ A + A YPITP + I E +A + + Y+ +E E Sbjct: 3 YKPIRKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 62 Query: 88 IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147 +++AA +GAS TG + TATS G +LM E L +A P+V+VDV R+ + + Sbjct: 63 HSAMAACIGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRA-MAPPWSVW 121 Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-ILGHT 206 Q D R D + + ++ + + A+ VAE + P +V+ IL HT Sbjct: 122 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAYKVAETVNVPAMVVESAFILSHT 176 Query: 207 REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTH-------VT 259 + V +PQ + LP P PL+ F T Sbjct: 177 YD------------VVEMIPQELVDEFLP---------PRKPLYSLANFDEPIAVGALAT 215 Query: 260 GSTHKENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSA 317 + + E + E K+++ + ++ + R+ + E Y DDA+ + + G Sbjct: 216 PNDYYEFRYKLAKAHEEAKKVIKEVGKEFGERFGRDYSQMIETGYIDDADFVFMGMGSLM 275 Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366 AV RKEG KVG + PFP E + E+ + V+ I V + N Sbjct: 276 GTVKEAVDLLRKEGYKVGYAKVRWFRPFPKEELVEIAESVKGIAVLDRN 324 >pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 - Pyrococcus abyssi (strain Orsay) >gi|5458781|emb|CAB50268.1| (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1) (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus abyssi] Length = 395 Score = 108 bits (266), Expect = 2e-22 Identities = 102/337 (30%), Positives = 155/337 (45%), Gaps = 26/337 (7%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 M +EA A+ A A + A +PITPS+ + E ++ + ++ ++++E E ++I+A+ Sbjct: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 VGAS G++ TAT+ G +LM E L A P+V+ R+ + Q Sbjct: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211 Q G + + ++A + A+ VAE R+ P +V FD IL HT E + Sbjct: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Query: 212 IPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270 IPD E+V L + E + A L P G P H EN + Sbjct: 181 IPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFP--AHYMEARYLVWEAMENARKV 235 Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330 + E + ++ RK Y+K EEY TDDAEI+ V+ G A V K R+E Sbjct: 236 I--DEAFAEFEKKFGRK-------YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREE 286 Query: 331 GIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367 G KVG PFP E +REL KK + + E ++ Sbjct: 287 GYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDI 323 >pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit - Pyrococcus horikoshii >gi|3257092|dbj|BAA29775.1| (AP000003) 398aa long hypothetical ferredoxin oxidoreductase alpha-2 subunit [Pyrococcus horikoshii] Length = 398 Score = 107 bits (265), Expect = 2e-22 Identities = 103/337 (30%), Positives = 153/337 (44%), Gaps = 26/337 (7%) Query: 30 YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87 + P M +EA A+ A A + A +PITPS+ + E ++ + ++ ++++E E Sbjct: 3 FMPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESE 62 Query: 88 IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147 ++I+A+VGAS G++ TAT+ G +LM E L A P+V+ RS + Sbjct: 63 HSAISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWN 122 Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILG 204 Q Q G + + ++A + A+ VAE R+ P +V FD IL Sbjct: 123 DWQDSISQRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILT 176 Query: 205 HTREQIRIPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTH 263 HT E + IPD E+V L + E + A L P G P V + Sbjct: 177 HTVEPVEIPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAME 233 Query: 264 KENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGA 323 K + D E + +R RK Y+K EEY TDDAEI+ V+ G A Sbjct: 234 KARKVID----EAFAEFEKRFGRK-------YQKIEEYKTDDAEIIFVTMGSLAGTLKDW 282 Query: 324 VLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAI 360 V K R+EG KVG PFP E +R L KK + + Sbjct: 283 VDKKREEGYKVGAAKMTVYRPFPVEEIRALAKKAKVL 319 >sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 395 Score = 106 bits (263), Expect = 4e-22 Identities = 102/330 (30%), Positives = 151/330 (44%), Gaps = 26/330 (7%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 M +EA A+ A A + A +PITPS+ + E ++ + ++ ++++E E ++I+A+ Sbjct: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAV 66 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 VGAS G++ TAT+ G +LM E L A P+V+ RS + Q Sbjct: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWNDWQDSIS 126 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211 Q G + + ++A + A+ VAE R+ P +V FD IL HT E + Sbjct: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Query: 212 IPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270 IPD E+V L + E + A L P G P V + K + D Sbjct: 181 IPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVID 237 Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330 E + +R RK Y+K EEY TDDAEI+ V+ G A V K R+E Sbjct: 238 ----EAFAEFEKRFGRK-------YQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREE 286 Query: 331 GIKVGLFVPKTVHPFPGERMRELGKKVRAI 360 G KVG PFP E +R L KK + + Sbjct: 287 GYKVGAAKMTVYRPFPVEEIRALAKKAKVL 316 >pir||A71114 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3257088|dbj|BAA29771.1| (AP000003) 397aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 397 Score = 106 bits (262), Expect = 5e-22 Identities = 97/347 (27%), Positives = 158/347 (44%), Gaps = 29/347 (8%) Query: 27 RKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQM 84 R Y P + G+ A AY A+ A + A YPITP + I E +A + + Y+ + Sbjct: 3 RMEYNPIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV 62 Query: 85 EDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQ 144 E E +++AA +GAS TG +V TATS G +LM E L +A + P+V+V+V R+ + Sbjct: 63 ESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRA-MAPPW 121 Query: 145 ATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-IL 203 + Q D R D + + ++ + + A+ VAE + P +++ IL Sbjct: 122 SVWDDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFIL 176 Query: 204 GHTREQIR-IPDPDEVEIVYRKLPQNEEEARL-PFGDPHGDGVPPMPLFGHGYFTHVTGS 261 HT E + IP E+V LP + L F +P G P + F + Sbjct: 177 SHTYEVVNMIPQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPA-DYYEFRYKIAK 231 Query: 262 THKENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSARP 319 H+E K+++ + ++ + R+ + E Y +DA+ + + G Sbjct: 232 AHEE-----------AKKVIKSVGKEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGT 280 Query: 320 SLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366 AV RKEG KVG + PFP E + E+ + V+ I V + N Sbjct: 281 VKEAVDLLRKEGYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 327 >sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 394 Score = 106 bits (261), Expect = 6e-22 Identities = 96/344 (27%), Positives = 157/344 (44%), Gaps = 29/344 (8%) Query: 30 YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87 Y P + G+ A AY A+ A + A YPITP + I E +A + + Y+ +E E Sbjct: 3 YNPIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 62 Query: 88 IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147 +++AA +GAS TG +V TATS G +LM E L +A + P+V+V+V R+ + + Sbjct: 63 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRA-MAPPWSVW 121 Query: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-ILGHT 206 Q D R D + + ++ + + A+ VAE + P +++ IL HT Sbjct: 122 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHT 176 Query: 207 REQIR-IPDPDEVEIVYRKLPQNEEEARL-PFGDPHGDGVPPMPLFGHGYFTHVTGSTHK 264 E + IP E+V LP + L F +P G P + F + H+ Sbjct: 177 YEVVNMIPQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPA-DYYEFRYKIAKAHE 231 Query: 265 ENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSARPSLG 322 E K+++ + ++ + R+ + E Y +DA+ + + G Sbjct: 232 E-----------AKKVIKSVGKEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKE 280 Query: 323 AVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366 AV RKEG KVG + PFP E + E+ + V+ I V + N Sbjct: 281 AVDLLRKEGYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 324 >dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase alpha subunit [Hydrogenobacter thermophilus] Length = 400 Score = 106 bits (261), Expect = 6e-22 Identities = 110/391 (28%), Positives = 170/391 (43%), Gaps = 54/391 (13%) Query: 35 YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVG--GYYLQMEDEIASIA 92 +FM G EAV A YPITP SE A + EL G G Y + E E ++ Sbjct: 31 HFMTGSEAVKEAVKRASVDASVSYPITPQSEAAHLIG-ELWVEGYVGVYFRGESEFGVMS 89 Query: 93 AMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGD 152 + G + G + +T TSGPG EN T P+ LV + R A Q D Sbjct: 90 EIAGCALAGARTITTTSGPGTLRAMENFPMWAGTRIPVQLVLMARGV----NAPLSIQPD 145 Query: 153 FFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDGI-LGHTREQ 209 + + D + + +D F + F VAE+ + PV+ + DG + HTRE Sbjct: 146 NLEVSFLL--DTGCMIWYAETAQDLFDMILAGFVVAEQPDVHVPVITVVDGFFVSHTRET 203 Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLR 269 + +P PD++ + P N A +P D VPP G F LR Sbjct: 204 VMLP-PDDIALP----PYNPYRAPMPVIDAE---VPP------GRF------------LR 237 Query: 270 DVYTQE-------VHDKLVRRIHRKIEQNREVYEKY-----EEYYTDDAEILVVSWGVSA 317 D + + H + IE++R + Y E + +A+++ V+ G ++ Sbjct: 238 DPFVMKSNYISYATHASWQWEVRAAIERSRPYAKHYLRGLIEHFGDPEADLVFVACGTAS 297 Query: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN-LGQMILEVQR 376 + AV EGI + KT+ PFP E +RE K + I VPE N +G + EV+R Sbjct: 298 AQAKEAVRMLEDEGISARVVKLKTIRPFPIEELREATKGAKYIFVPEFNVVGWLEREVRR 357 Query: 377 FV--NDDVLLKGVNKI-GGVPLTVEEILREI 404 ++ + + G ++ GG+ + E I+RE+ Sbjct: 358 YLYGHSSAEIIGAPRVAGGMTMPAEVIVREV 388 >sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7449945|pir||E69099 pyruvate synthase (EC 1.2.7.1) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622870|gb|AAB86209.1| (AE000929) pyruvate oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 383 Score = 104 bits (256), Expect = 3e-21 Identities = 102/378 (26%), Positives = 172/378 (44%), Gaps = 37/378 (9%) Query: 40 DEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAMVGA 97 ++AVA A A + YPITP + I+E +A+ + ++ Y+++E E ++++A VGA Sbjct: 9 NQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFVADGELKAEYIRVESEHSAMSACVGA 68 Query: 98 SWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQAR 157 S G++V TATS G +LM E + A P+V+ + R+ S + Q D R Sbjct: 69 SGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRA-LSAPLSIWNDQQDSIAER 127 Query: 158 WGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIRIPD 214 D + I S ++A + ++ V+E + P +V DG IL HT E + IP Sbjct: 128 -----DSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEPVDIPS 182 Query: 215 PDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQ 274 ++V+ LP+ + + L +P G P Y+ K Sbjct: 183 QEDVDSF---LPEFQPQVMLDPDEPMSLGTFTDP----DYYMEARYEVEK--------AM 227 Query: 275 EVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGI 332 E K++ R R+ + RE Y EEY +DAEI++V+ G + + R +G Sbjct: 228 ERSRKIIERACREFSEMFGRE-YGLVEEYRCEDAEIILVAMGSVCSTLREVIDELRDKGK 286 Query: 333 KVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-----GQMILEVQRFVNDDVLLKGV 387 VGL + PFP E ++ + + V + N+ G + E+ + D + + Sbjct: 287 AVGLLKVRVHRPFPAEEIKSAVRNASKVAVLDKNITFSVGGALYTEISALLRDREVYGFI 346 Query: 388 NKIGG---VPLTVEEILR 402 +GG P +EEI+R Sbjct: 347 VGLGGRDITPAHIEEIVR 364 >sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280155|pir||T45088 pyruvate synthase (EC 1.2.7.1) alpha-2 chain [imported] - Pyrococcus furiosus >gi|1197363|emb|CAA59505.1| (X85250) pyruvate ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus] Length = 396 Score = 103 bits (255), Expect = 3e-21 Identities = 96/336 (28%), Positives = 155/336 (45%), Gaps = 24/336 (7%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 M +EA A+ A A + A +PITPS+ I E ++ + ++ ++++E E ++I+A Sbjct: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAISAC 66 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 VGA+ G++ TAT+ G +LM E L A P+V+ R+ + Q Sbjct: 67 VGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211 Q G + + ++A + A+ VAE R+ P +V FD IL HT E + Sbjct: 127 QRDTGW------MQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271 IPD + V+ E E + + DP P+ + H S + + Sbjct: 181 IPDQEVVDEFL-----GEYEPKHAYIDP----ARPITQGSLAFPAHYMESRYTVWEAME- 230 Query: 272 YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG 331 ++V D+ +K + Y+K EEY T+DA+I+ V+ G A + K R+EG Sbjct: 231 RAKKVIDEAFAEFEKKFGRK---YQKIEEYKTEDADIIFVTMGSLAGTLNEWIDKKREEG 287 Query: 332 IKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367 KVG PFP E +REL KK + + E N+ Sbjct: 288 YKVGAAKITVYRPFPVEEIRELAKKAKVLAFLEKNI 323 >gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-2) [Sulfolobus solfataricus] Length = 400 Score = 100 bits (246), Expect = 4e-20 Identities = 102/385 (26%), Positives = 182/385 (46%), Gaps = 48/385 (12%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVG 96 G+EAVA G A YPITP + I E +A R ++ +++E E +++AA G Sbjct: 8 GNEAVALGVKLARVGVTGIYPITPQTTIIEKLAEMRAKGEIETEIVRVESEHSAMAATFG 67 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156 A+ G++ TAT+ G M E + + + P+V+V G GA + Sbjct: 68 AALGGVRAFTATASQGLLYMHEMVWWVAGSRVPVVMV--------VGTRAVGAPWNI--- 116 Query: 157 RWGTHGDHP-------IVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHT 206 W H D I+A + + ++A T++AF ++E R+ P+++ DG IL HT Sbjct: 117 -WNEHTDFTSERDSGWIMAFAS-NPQEALDLTLQAFRISEDERVFLPMMIGMDGFILSHT 174 Query: 207 REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDG--VPPMPLFGHGYFTHVTGSTHK 264 + + IPD D+V+ LP + + DP G G PP GY + Sbjct: 175 KTNVLIPDQDQVDDF---LPPRRQPYVIDPEDPVGMGNIFPP-----EGYMR-----LRE 221 Query: 265 ENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAV 324 L +++V ++ R ++KI + Y +DA+ VV G A ++ AV Sbjct: 222 SIDLALRNSEDVIKEIGREYNKKINPLGDYSTLNVSYKLEDADYAVVLMGAWAGDAMEAV 281 Query: 325 LKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL------GQMILEVQRFV 378 R++GIK+G+ + + P+ + +R K +A+LV + + G + +E++ + Sbjct: 282 DTLREKGIKIGMLRIRYLRPWSEKEIRNTLKDKKAVLVLDRSTSFGRGGGPLYVEIKSTI 341 Query: 379 NDDV-LLKG-VNKIGGVPLTVEEIL 401 ++ V +KG V+ +GGV + +++ Sbjct: 342 SNVVPQIKGVVSGLGGVTVNKNDLV 366 >emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin oxidoreductase alpha-2 chain [Thermoplasma acidophilum] Length = 402 Score = 98.7 bits (242), Expect = 1e-19 Identities = 93/351 (26%), Positives = 155/351 (43%), Gaps = 32/351 (9%) Query: 15 IRGDEPEQKELLRKLYKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMAREL 74 IRGD + R + M G++AVAYGA A +F + YPITP + I E +A + Sbjct: 6 IRGDRMKSVNEFRTI-------MTGNDAVAYGAKLARVKFISAYPITPQTTIVEKLASMI 58 Query: 75 --PKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVL 132 ++ Y+++E E +++AA+ + TG++ TATS G M E L + P+V+ Sbjct: 59 ANDELDAKYVEVESEHSALAAVFASELTGVRSYTATSSHGLLYMHEMLHWVAGQRLPIVM 118 Query: 133 VDVQRS-GPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER- 190 V R+ GP Q D R D + + S ++A I + +AE Sbjct: 119 SVVNRAIGPPWN--IWADQSDTINQR-----DTGWMQVYSESNQEAMDTIIMGYKIAENS 171 Query: 191 -LRTPVVVLFDG-ILGHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMP 248 + P++ + D IL HT E + + D D +V LP + + R+ +P G G P Sbjct: 172 GVMLPLMSMEDAFILSHTSEPVTMRDQD---LVNEYLPDLDLKFRIDPENPMGYGSYDTP 228 Query: 249 LFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEI 308 + N R V +E ++ + E N E Y DDA+ Sbjct: 229 --DGSFMEFKKDMIDSMNNARKVIKEE-----TQKFNEMFETNYGAL--IERYRMDDADY 279 Query: 309 LVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRA 359 +++ G A + + + R+ G+ +GL + PFP + + E K V++ Sbjct: 280 AIIAMGTVASTARFVIDRLRENGLNIGLIRIRYFRPFPYDEILEDLKNVKS 330 >pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus >gi|2983615|gb|AAC07184.1| (AE000726) ferredoxin oxidoreductase alpha subunit [Aquifex aeolicus] Length = 389 Score = 97.9 bits (240), Expect = 2e-19 Identities = 105/381 (27%), Positives = 163/381 (42%), Gaps = 39/381 (10%) Query: 36 FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGY---YLQMEDEIASIA 92 F+ G +A A A YPITP SE + + GY Y + E+E +++ Sbjct: 22 FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ--GYVKDYYRAEEEYGAMS 79 Query: 93 AMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGD 152 A+ GA G + TATSGPG E + P VL + R A Q D Sbjct: 80 AIAGAVRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLGVMTR----VVNAPLSIQPD 135 Query: 153 FFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRT--PVVVLFDGI-LGHTREQ 209 + + + +V + + +D F T+ F ++E++ PVVV +G + H + Sbjct: 136 NVEISYLLNSG--LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193 Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPP----MPLFGHGYFTHVTGSTHKE 265 + +P E+ +LP DP+ VPP +P V S Sbjct: 194 VELPP---------------EDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238 Query: 266 NGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVL 325 + V+ QEV R + + E DAE+ VV+ G +A A Sbjct: 239 YLIHAVWQQEVWSAN----RRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQR 294 Query: 326 KARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-GQMILEVQRFV-NDDVL 383 A EG+ VGL K++ PFP + +RE K +A++VPE N+ G + EV+ + N ++ Sbjct: 295 YATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIV 354 Query: 384 LKGVNKIGGVPLTVEEILREI 404 + G GG+ L VE I+ EI Sbjct: 355 VDGPRVYGGMTLPVELIMEEI 375 >gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-1) [Sulfolobus solfataricus] Length = 385 Score = 96.7 bits (237), Expect = 4e-19 Identities = 88/331 (26%), Positives = 153/331 (45%), Gaps = 25/331 (7%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 ++G+ AVAY A + A +PITP + + E ++ + ++ +++E E +++A++ Sbjct: 11 LVGNHAVAYAVKQAKPKVLAVFPITPQTTMLEKLSEYISSEELKAELIKVESEHSALASI 70 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 GA+ G +V TATS G M E + +A P+V R+ Q DF Sbjct: 71 YGAALAGARVFTATSSQGLLYMTEMIYWAGGQRVPIVAAVATRAIAEPWSIWDDHQ-DFV 129 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211 R D + I +V++A+ TI+AF ++E R+ PV++ FDG IL HT E+I Sbjct: 130 SKR-----DAIWIQIMAENVQEAYDMTIQAFRISEDERVILPVMMGFDGFILTHTMERIE 184 Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271 + + +EV+ LP + + F DP G P Y + + G+ + Sbjct: 185 VLEDNEVD---NFLPPRQFNL-IDFSDPIAIGPIATPEEYIKYRYEAMKAMERAKGVIEE 240 Query: 272 YTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEG 331 E R+ H +E Y +DA+ + V+ G + AV + R G Sbjct: 241 IMGEYERISGRKQHGLVEC----------YKCEDAKYVFVTMGAWSGDGKAAVDRLRDSG 290 Query: 332 IKVGLFVPKTVHPFPGERMRELGKKVRAILV 362 +K GL + PFP E++ E + ++ ++V Sbjct: 291 VKTGLLKIRVFRPFPKEKVEEYLRSMKGVVV 321 >gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA) [Archaeoglobus fulgidus] >gi|7449955|pir||D69506 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain AF2053 [similarity] - Archaeoglobus fulgidus >gi|2648476|gb|AAB89196.1| (AE000961) 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA) [Archaeoglobus fulgidus] Length = 366 Score = 96.3 bits (236), Expect = 6e-19 Identities = 100/383 (26%), Positives = 168/383 (43%), Gaps = 71/383 (18%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 + +EA+A A A YPITP S I E ++ + ++ ++++E E +++ + Sbjct: 17 LTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHSAMGVV 76 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 +GA+ G +V TATS G + M E +A + P+V+ RS Sbjct: 77 IGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAARS---------------I 121 Query: 155 QARWGTHGDHP----------IVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGI-L 203 A W HGDH I++++ + ++AF T+ AF ++E + PV V DG + Sbjct: 122 GAPWNIHGDHLDLMAMRDLGWIISVAE-NAQEAFDMTLNAFMLSEEVNIPVAVAIDGFTM 180 Query: 204 GHTREQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTH 263 HT E + + EVEI P ++ R+ +P M + Sbjct: 181 SHTAEVVEV---REVEI-----PPRKQAYRI---------LPGMDV-------------- 209 Query: 264 KENGLRDVYTQEVHDKLVRRIHRKIEQNREVYEK-----YEEYYTDDAEILVVSWGVSAR 318 L V E + + +E + E+ EK E Y +DA+ VV G + Sbjct: 210 ---ALNAVTFGEARMTARYDLAKDLENSAELIEKEYGGLVERYRLEDADYAVVVTGGLSG 266 Query: 319 PSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-GQMILEVQRF 377 AV R+EG+K+G+ K + PFP + ++ L +V + +L G + +EV Sbjct: 267 DVKDAVDMLREEGVKMGVLRLKFIRPFPKKAVKSLPSQVLVVDRANTDLRGTLSVEVAAC 326 Query: 378 VNDDVLLKGVNKIGGVPLTVEEI 400 ++V + V IGG TVEE+ Sbjct: 327 GVENVNV--VAGIGGRYPTVEEL 347 >gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alpha subunit [Methanococcus maripaludis] Length = 387 Score = 95.6 bits (234), Expect = 9e-19 Identities = 93/381 (24%), Positives = 161/381 (41%), Gaps = 42/381 (11%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAMVG 96 G A A A A A YPITP + E +A + ++ Y+++E E ++++A +G Sbjct: 9 GTSAAAEAAKLADVDVIAAYPITPQTTCVEKLADFVANGELNAEYIKVESEHSAMSASIG 68 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQA 156 AS G + TATS G +LM E L A P+V+++ R+ + Q Q Sbjct: 69 ASAAGARAFTATSSQGLALMHEVLFAAAGMRVPVVMMNANRALSAPINIWNDQQDSLSQR 128 Query: 157 RWGTHGDHPIVAISPVSVEDAFWETIRAFNVA--ERLRTPVVVLFDG-ILGHTREQIRIP 213 G + + ++ I+AF +A E++ PV+V DG IL HT E + +P Sbjct: 129 DTGW------IQLYAEDNQEVLDLVIQAFKIAEDEKVLLPVMVNLDGFILTHTVEPVTLP 182 Query: 214 DPDEV-------EIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKEN 266 + V E + L + + GDP+ + T T EN Sbjct: 183 KQENVLDFIGTYEPKHAYLDPKKPMTQGALGDPN-----------YYMETRYAIETAMEN 231 Query: 267 GLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLK 326 + + +VHD + +R E Y + AE ++V+ G + Sbjct: 232 AKKVI--ADVHDAFAEKFNRAYGNG-----LIESYNLEKAENVIVAMGSICGTIKDMIDL 284 Query: 327 ARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPE------MNLGQMILEVQRFVND 380 +KEG+++GL + P P E +++ K + + + + MN G + +V + D Sbjct: 285 KKKEGVEIGLLKIRCYRPLPIEMIKDALKNAKNVAILDKSISLGMNKGAIYADVASHLKD 344 Query: 381 DVLLKGVNKIGGVPLTVEEIL 401 + + +GG +T E+IL Sbjct: 345 KKTVNYIVGLGGRDITPEDIL 365 >pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus >gi|2983644|gb|AAC07211.1| (AE000728) ferredoxin oxidoreductase alpha subunit [Aquifex aeolicus] Length = 404 Score = 94.4 bits (231), Expect = 2e-18 Identities = 106/392 (27%), Positives = 166/392 (42%), Gaps = 51/392 (13%) Query: 35 YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVG--GYYLQMEDEIASIA 92 +F+ G EAV A A YPITP SE A M EL + G G Y + E E ++ Sbjct: 34 HFITGSEAVKEAAKRASVDASISYPITPQSEAAH-MLGELWREGYIGVYFRGESEFGVMS 92 Query: 93 AMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGD 152 + G + G + +T TSGPG E + P+ LV + R S Sbjct: 93 EVAGCAMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMARGINSPLSIQPDNLEI 152 Query: 153 FFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDGI-LGHTREQ 209 F G H A ++ F I F VAE+ + P++ DG + HTRE Sbjct: 153 SFLLDTGCMVWHAETA------QELFDMIIAGFVVAEQPDVHVPIITAIDGFFISHTREA 206 Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGD---PHGDGVPPMPLFGHGYFTHVTGSTHKEN 266 + +P P+++ + P N +A +P D P G + + Y ++ T Sbjct: 207 VYLP-PEDIALP----PYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISYAT------- 254 Query: 267 GLRDVYTQEVHDKLVRRIHRKIEQNREVYEKY-----EEYYTDDAEILVVSWGVSARPSL 321 H + IE++R + Y E + + E+L ++ G +A + Sbjct: 255 ----------HASWQFEVRAAIERSRPYAKHYLRGLVEHFGDPEGEVLFIASGTAAAQAK 304 Query: 322 GAV-LKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN-LGQMILEVQR--F 377 A + +EGIK + KT+ PFP E +RE K + I +PE N +G + EV+R + Sbjct: 305 EATQILIHEEGIKARVLRLKTLRPFPTEEVREAVKGAKYIFIPEFNVVGWLEREVKRALY 364 Query: 378 VNDDVLLKGVNKIGG-----VPLTVEEILREI 404 D+ + G ++GG V+E+LR I Sbjct: 365 GYTDIPIFGTPRVGGGMTMPPEFIVQEVLRLI 396 >pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicobacter pylori (strain 26695) >gi|2314261|gb|AAD08154.1| (AE000617) pyruvate ferredoxin oxidoreductase, alpha subunit [Helicobacter pylori 26695] Length = 407 Score = 94.0 bits (230), Expect = 3e-18 Identities = 90/330 (27%), Positives = 156/330 (47%), Gaps = 31/330 (9%) Query: 56 AGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGF 113 A YPITPS+ I + ++ V G ++ +E E A+++A VGA+ G +V TATS G Sbjct: 32 AAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVGAAAAGGRVSTATSSQGL 91 Query: 114 SLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVS 173 +LM E L A P+VL V R+ + G D + +R D +++ + Sbjct: 92 ALMVEVLYQASGMRLPIVLNLVNRA-LAAPLNIHGDHSDMYLSR-----DSGWISLCTCN 145 Query: 174 VEDAFWETIRAFNVAE--RLRTPVVVLFDGIL-GHTREQIRIPDPDEVEIVYRKLPQNE- 229 ++A+ T+ AF +AE ++R P +V DG L HT + +R P + Y+ + + + Sbjct: 146 PQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVR---PLSDAVAYQFVGEYQT 202 Query: 230 EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE 289 + + L F P G + ++ H H V +EV + + R+ Sbjct: 203 KHSLLDFDKPVSYGAQAEEEW---HYEHKAQLHHAIMSASSVI-EEVFNDFAKLTGRQ-- 256 Query: 290 QNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGER 349 Y + + +DAEI + + G + ++ A + RK+GIK G+ ++ PFP ER Sbjct: 257 -----YHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311 Query: 350 MRELGKKVRAILV-----PEMNLGQMILEV 374 + + K ++A+ + P +G M EV Sbjct: 312 LGQDLKNLKALAILDKSSPAGTMGAMFNEV 341 >pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter pylori (strain J99) >gi|4155626|gb|AAD06616.1| (AE001531) Pyruvate ferrodoxin oxidoreductase [Helicobacter pylori J99] Length = 407 Score = 93.2 bits (228), Expect = 5e-18 Identities = 90/330 (27%), Positives = 156/330 (47%), Gaps = 31/330 (9%) Query: 56 AGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGF 113 A YPITPS+ I + ++ V G ++ +E E A+++A VGA+ G +V TATS G Sbjct: 32 AAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVGAAAAGGRVSTATSSQGL 91 Query: 114 SLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVS 173 +LM E L A P+VL V R+ + G D + +R D +++ + Sbjct: 92 ALMVEVLYQASGMRLPIVLNLVNRA-LAAPLNIHGDHSDMYLSR-----DSGWISLCTCN 145 Query: 174 VEDAFWETIRAFNVAE--RLRTPVVVLFDGIL-GHTREQIRIPDPDEVEIVYRKLPQNE- 229 ++A+ T+ AF +AE ++R P +V DG L HT + +R P + Y+ + + + Sbjct: 146 PQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVR---PLSDAVAYQFVGEYQT 202 Query: 230 EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE 289 + + L F P G + ++ H H V +EV + + R+ Sbjct: 203 KHSLLDFDKPVSYGAQAEEEW---HYEHKAQLHHAIMSASSVI-EEVFNDFAKLTGRQ-- 256 Query: 290 QNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGER 349 Y + + +DAEI + + G + ++ A + RK+GIK G+ ++ PFP ER Sbjct: 257 -----YHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311 Query: 350 MRELGKKVRAILV-----PEMNLGQMILEV 374 + + K ++A+ + P +G M EV Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEV 341 >gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit [Helicobacter pylori] Length = 396 Score = 91.7 bits (224), Expect = 1e-17 Identities = 88/330 (26%), Positives = 155/330 (46%), Gaps = 31/330 (9%) Query: 56 AGYPITPSSEIAETMA--RELPKVGGYYLQMEDEIASIAAMVGASWTGLKVMTATSGPGF 113 A YPITPS+ I + ++ + G ++ +E E A+++A VGA+ G +V TATS G Sbjct: 32 AAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMSACVGAAAAGGRVSTATSSQGL 91 Query: 114 SLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQARWGTHGDHPIVAISPVS 173 +LM E L A P+VL V R+ + G D + +R D +++ + Sbjct: 92 ALMVEVLYQASGMRLPIVLNLVNRA-LAAPLNIHGDHSDMYLSR-----DSGWISLCTCN 145 Query: 174 VEDAFWETIRAFNVAE--RLRTPVVVLFDGIL-GHTREQIRIPDPDEVEIVYRKLPQNE- 229 ++A+ T+ AF +AE ++R P +V DG L HT + +R P + Y+ + + + Sbjct: 146 PQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCSHTVQNVR---PLSDAVAYQFVGEYQT 202 Query: 230 EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQEVHDKLVRRIHRKIE 289 + + L F P G ++ H H V +EV + + R+ Sbjct: 203 KHSLLDFDKPVSYGAQAEE---EWHYEHKAQLHHAIMSASSV-IEEVFNDFAKLTGRQ-- 256 Query: 290 QNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGER 349 Y + + +DAEI + + G + ++ A + RK+GIK G+ ++ PFP E+ Sbjct: 257 -----YHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYEK 311 Query: 350 MRELGKKVRAILV-----PEMNLGQMILEV 374 + + K ++A+ + P +G M EV Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEV 341 >emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase [Thermotoga maritima] >gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate ferredoxin oxidoreductase, alpha subunit [Thermotoga maritima] Length = 394 Score = 83.1 bits (202), Expect = 5e-15 Identities = 101/340 (29%), Positives = 150/340 (43%), Gaps = 32/340 (9%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPK--VGGYYLQMEDEIASIAAMVG 96 G EAVA A YPITP + I E AR + V + +E E ++++A+VG Sbjct: 14 GAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAVVG 73 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQR--SGPSTGQATKGAQGDFF 154 A+ G + MTATS G +LM E + A P+V+ V R SGP D Sbjct: 74 AAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCD---HSDAM 130 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDG-ILGHTREQIR 211 R D + + + ++A+ TI A +AE +R PV+V DG IL H E + Sbjct: 131 AER-----DSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVE 185 Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGD-PHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270 PDE+ K E + P D H P+ L+ + YF H ++ Sbjct: 186 F-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDY-YFEHKRQQIEAMENVKK 239 Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330 V+ E+ + RK Y E Y +DAE ++V+ G + V + R+E Sbjct: 240 VF-PEIAKEFEETFGRK-------YWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREE 291 Query: 331 GIKVGLFVPKTVHPFPGERMREL--GKKVRAILVPEMNLG 368 G KVG PFP E+++EL G+K +L ++ G Sbjct: 292 GYKVGSLKIWMFRPFPKEQLQELLNGRKSVVVLDRAVSFG 331 >sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7449946|pir||C72427 pyruvate synthase (EC 1.2.7.1) alpha chain - Thermotoga maritima (strain MSB8) Length = 392 Score = 83.1 bits (202), Expect = 5e-15 Identities = 101/340 (29%), Positives = 150/340 (43%), Gaps = 32/340 (9%) Query: 39 GDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPK--VGGYYLQMEDEIASIAAMVG 96 G EAVA A YPITP + I E AR + V + +E E ++++A+VG Sbjct: 12 GAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAVVG 71 Query: 97 ASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQR--SGPSTGQATKGAQGDFF 154 A+ G + MTATS G +LM E + A P+V+ V R SGP D Sbjct: 72 AAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCD---HSDAM 128 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAER--LRTPVVVLFDG-ILGHTREQIR 211 R D + + + ++A+ TI A +AE +R PV+V DG IL H E + Sbjct: 129 AER-----DSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVE 183 Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGD-PHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270 PDE+ K E + P D H P+ L+ + YF H ++ Sbjct: 184 F-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDY-YFEHKRQQIEAMENVKK 237 Query: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330 V+ E+ + RK Y E Y +DAE ++V+ G + V + R+E Sbjct: 238 VF-PEIAKEFEETFGRK-------YWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREE 289 Query: 331 GIKVGLFVPKTVHPFPGERMREL--GKKVRAILVPEMNLG 368 G KVG PFP E+++EL G+K +L ++ G Sbjct: 290 GYKVGSLKIWMFRPFPKEQLQELLNGRKSVVVLDRAVSFG 329 >gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta subunit [Prevotella albensis] Length = 104 Score = 76.9 bits (186), Expect = 4e-13 Identities = 41/88 (46%), Positives = 54/88 (60%), Gaps = 2/88 (2%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 M G+EA+A+ AI G + GYPITP SEI ET+A P G LQ E E+ASI + Sbjct: 8 MKGNEAIAHAAIRCGADGFFGYPITPQSEIIETLALLKPWETTGMVVLQAESEVASINML 67 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGY 122 G + G +V+T +S PG +LMQE + Y Sbjct: 68 YGGAGAGKRVLTTSSSPGVALMQEGIAY 95 >gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-like) [Sulfolobus solfataricus] Length = 415 Score = 75.7 bits (183), Expect = 9e-13 Identities = 87/408 (21%), Positives = 169/408 (41%), Gaps = 69/408 (16%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 M G +AVA+ A++A A YPI P +E+ +T+++ + ++ ++ E E + Sbjct: 14 MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 AS G + + +SG G+ E + P+V + R+ G A D Sbjct: 74 KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPG-AYGVEHNDAL 132 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211 R D + + + ++AF + A+ +AE R+ P+ + DG L H+ + +R Sbjct: 133 MVR-----DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187 Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271 +P R+L +N F P+ G Y H + + Sbjct: 188 LPP--------RELVKN-------FLPPYNRGK---------YLVHPDNPITVAPQVNED 223 Query: 272 YTQEV---HDKLVRRIHRKI----EQNREVYEKY---------------EEYYTDDAEIL 309 + E+ H++ + R I E+ ++V+ +Y E Y DDAE++ Sbjct: 224 WVMEIRRQHEEAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVV 283 Query: 310 VVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEM---- 365 ++ G ++P A+ R++G KVG+ + PFP + + R + V + Sbjct: 284 LIGMGTVSKPMKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSM 343 Query: 366 ---NLGQMILEVQRFVNDDV-----LLKGVNKIGGVPLTVEEILREIR 405 N G +I R D+ ++ + +GG +T++++ + I+ Sbjct: 344 GSPNRGGVIYHEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391 >pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolobus solfataricus >gi|1707735|emb|CAA69455.1| (Y08256) pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus solfataricus] Length = 415 Score = 75.7 bits (183), Expect = 9e-13 Identities = 87/408 (21%), Positives = 169/408 (41%), Gaps = 69/408 (16%) Query: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 M G +AVA+ A++A A YPI P +E+ +T+++ + ++ ++ E E + Sbjct: 14 MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73 Query: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 AS G + + +SG G+ E + P+V + R+ G A D Sbjct: 74 KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPG-AYGVEHNDAL 132 Query: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211 R D + + + ++AF + A+ +AE R+ P+ + DG L H+ + +R Sbjct: 133 MVR-----DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187 Query: 212 IPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271 +P R+L +N F P+ G Y H + + Sbjct: 188 LPP--------RELVKN-------FLPPYNRGK---------YLVHPDNPITVAPQVNED 223 Query: 272 YTQEV---HDKLVRRIHRKI----EQNREVYEKY---------------EEYYTDDAEIL 309 + E+ H++ + R I E+ ++V+ +Y E Y DDAE++ Sbjct: 224 WVMEIRRQHEEAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVV 283 Query: 310 VVSWGVSARPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEM---- 365 ++ G ++P A+ R++G KVG+ + PFP + + R + V + Sbjct: 284 LIGMGTVSKPMKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSM 343 Query: 366 ---NLGQMILEVQRFVNDDV-----LLKGVNKIGGVPLTVEEILREIR 405 N G +I R D+ ++ + +GG +T++++ + I+ Sbjct: 344 GSPNRGGVIYHEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391 >pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alpha (iora-1) PAB0855 - Pyrococcus abyssi (strain Orsay) >gi|5458715|emb|CAB50202.1| (AJ248287) indolepyruvate ferredoxin oxidoreductase, subunit alpha (iorA-1) [Pyrococcus abyssi] Length = 648 Score = 70.6 bits (170), Expect = 3e-11 Identities = 58/209 (27%), Positives = 92/209 (43%), Gaps = 17/209 (8%) Query: 31 KPGN-YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIA 89 KPG ++G++A+ GA+ YA YP TPSSEI +TMA + G Y +E Sbjct: 12 KPGERVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAAVASRAGVYMEYSTNEKV 71 Query: 90 SIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGA 149 + + ASW GL+ MTA G ++ ++ LV V PS +++ Sbjct: 72 AFETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGVNGGLVVVVADDPSM-WSSQNE 130 Query: 150 QGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQ 209 Q A++ I + P SV++A AF ++E+ V++ H R Sbjct: 131 QDTRAIAKFAN-----IPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG- 184 Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGD 238 ++V +LPQ +E + FGD Sbjct: 185 ---------DVVLGELPQEIKEGKRKFGD 204 >sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7450338|pir||F71124 probable indolepyruvate ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3257173|dbj|BAA29856.1| (AP000003) 648aa long hypothetical indolepyruvate ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 648 Score = 69.1 bits (166), Expect = 9e-11 Identities = 57/209 (27%), Positives = 92/209 (43%), Gaps = 17/209 (8%) Query: 31 KPGN-YFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIA 89 KPG ++G++A+ GA+ YA YP TPSSEI +TMA K G Y +E Sbjct: 12 KPGEKVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAMVAKKAGVYMEYSTNEKV 71 Query: 90 SIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGA 149 + + ASW GL+ MTA G ++ ++ L+ V PS +++ Sbjct: 72 AFETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGINGGLIVVVADDPSM-WSSQNE 130 Query: 150 QGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQ 209 Q A++ I + P SV++A AF ++E+ V++ H R Sbjct: 131 QDTRAIAKFAN-----IPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG- 184 Query: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGD 238 ++V +LPQ +E + FG+ Sbjct: 185 ---------DVVLGELPQEIKEGKRKFGN 204 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.140 0.417 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 165402996 Number of Sequences: 2977 Number of extensions: 7505885 Number of successful extensions: 15791 Number of sequences better than 1.0e-10: 60 Number of HSP's better than 0.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 15648 Number of HSP's gapped (non-prelim): 64 length of query: 408 length of database: 189,106,746 effective HSP length: 54 effective length of query: 354 effective length of database: 156,788,448 effective search space: 55503110592 effective search space used: 55503110592 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 166 (69.1 bits)