BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2364 (metS) DE:methionyl-tRNA synthetase (metS)
(722 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75074 methionyl-tRNA synthetase (mets) PAB2364 - Pyrococcu... 1499 0.0
sp|O58721|SYM_PYRHO METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 1410 0.0
sp|O26687|SYM_METTH METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 598 e-169
sp|Q58659|SYM_METJA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 564 e-160
emb|CAC12287.1| (AL445066) probable methionyl-tRNA synthetase [T... 482 e-135
gi|11499048 methionyl-tRNA synthetase (metS) [Archaeoglobus fulg... 474 e-132
pir||T05247 methionine--tRNA ligase homolog F18A5.170 - Arabidop... 474 e-132
sp|Q9YCY3|SYM_AERPE METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 467 e-130
gb|AAC99620.1| (AF040700) methionyl-tRNA synthetase [Oryza sativa] 462 e-129
emb|CAB57741.1| (Y18930) methionyl-trna synthetase [Sulfolobus s... 444 e-123
gb|AAK40875.1| Methionyl-tRNA synthetase (metS) [Sulfolobus solf... 444 e-123
gb|AAG18903.1| (AE004992) methionine-tRNA synthetase; MetS [Halo... 430 e-119
sp|Q44951|SYM_BORBU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 415 e-114
sp|O83776|SYM_TREPA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 403 e-111
dbj|BAA95668.1| (D84224) methionyl tRNA synthetase [Homo sapiens] 399 e-110
gi|4826826 methionine-tRNA synthetase; Methioninyl-tRNA syntheta... 398 e-109
pir||H81552 methionyl-tRNA synthetase CP0651 [imported] - Chlamy... 394 e-108
pir||H81718 methionyl-tRNA synthetase TC0301 [imported] - Chlamy... 393 e-108
sp|Q9Z959|SYM_CHLPN METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 392 e-108
sp|O84035|SYM_CHLTR METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 391 e-107
sp|P00959|SYM_ECOLI METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 382 e-105
gb|AAA60526.1| (U00007) methionyl-tRNA synthetase [Escherichia c... 382 e-105
pir||D82249 methionyl-tRNA synthetase VC1036 [imported] - Vibrio... 378 e-103
emb|CAA24627.1| (V01316) tRNA synthetase [Saccharomyces cerevisi... 374 e-102
gi|6321704 methionyl tRNA synthetase; Mes1p [Saccharomyces cerev... 374 e-102
sp|Q20970|SYM_CAEEL PROBABLE METHIONYL-TRNA SYNTHETASE (METHIONI... 371 e-101
sp|P43828|SYM_HAEIN METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 368 e-100
pir||T39696 methionyl trna synthetase - fission yeast (Schizosa... 364 2e-99
dbj|BAA21422.1| (AB004537) methionyl-tRNA synthetase [Schizosacc... 364 2e-99
pir||C83210 methionyl-tRNA synthetase PA3482 [imported] - Pseudo... 345 1e-93
pir||C82792 methionyl-tRNA synthetase XF0549 [imported] - Xylell... 344 2e-93
pir||G82022 methionine--tRNA ligase (EC 6.1.1.10) NMA0275 [impor... 339 5e-92
pir||A81246 methionyl-tRNA synthetase NMB0030 [imported] - Neiss... 339 7e-92
sp|P23920|SYM_BACST METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 324 2e-87
pdb|1QQT|A Chain A, Methionyl-Trna Synthetase From Escherichia Coli 323 6e-87
sp|O33925|SYM_THEMA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 316 6e-85
dbj|BAB03772.1| (AP001507) methionyl-tRNA synthetase [Bacillus h... 297 2e-79
sp|P57210|SYM_BUCAI METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 283 4e-75
sp|P37465|SYM_BACSU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 280 3e-74
sp|P23395|SYM_THETH METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 280 5e-74
pir||F81356 methionine--tRNA ligase (EC 6.1.1.10) Cj0838c [impor... 273 4e-72
pir||C75395 methionyl-tRNA synthetase - Deinococcus radiodurans ... 269 7e-71
emb|CAA89153.1| (Z49216) mitoxantrone-resistance associated gene... 250 3e-65
sp|Q9ZKG9|SYM_HELPJ METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 242 1e-62
sp|P56127|SYM_HELPY METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 236 8e-61
emb|CAC10330.1| (AL442629) putative methionyl tRNA synthetase [S... 218 2e-55
sp|O67298|SYM_AQUAE METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 215 1e-54
sp|Q9ZCP0|SYM_RICPR METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 204 3e-51
pir||T47679 methionine--tRNA ligase (EC 6.1.1.10) - Arabidopsis ... 200 4e-50
sp|Q55729|SYM_SYNY3 METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 200 5e-50
emb|CAB98261.1| (AL390096) methionyl-tRNA synthetase [Leishmania... 193 5e-48
pir||T50641 methionine--tRNA ligase (EC 6.1.1.10) [imported] - A... 193 7e-48
pdb|1A8H| Methionyl-Trna Synthetase From Thermus Thermophilus 190 6e-47
sp|O05593|SYM_MYCTU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 190 6e-47
pir||C82922 methionyl-tRNA synthetase UU197 [imported] - Ureapla... 179 8e-44
sp|P47267|SYM_MYCGE METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 166 1e-39
sp|P75091|SYM_MYCPN METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 163 7e-39
sp|Q9ZHD7|SYM_BUCAP METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 161 2e-38
emb|CAB81970.1| (AL132880) predicted using Genefinder; prelimina... 152 2e-35
pir||T35923 probable tRNA synthetase - Streptomyces coelicolor >... 150 4e-35
pir||T38454 methionyl-trna synthetase, mitochondrial - fission y... 149 1e-34
emb|CAA32778.1| (X14629) methionyl-tRNA synthase (AA 1 - 575) [S... 127 3e-28
gi|6321610 mitochondrial methionyl-tRNA synthetase; Msm1p [Sacch... 127 3e-28
gb|AAF55037.1| (AE003703) CG8684 gene product [Drosophila melano... 121 2e-26
sp|O74634|SYMM_CANAL METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL (M... 115 1e-24
pir||F70338 methionine--tRNA ligase (EC 6.1.1.10) beta - Aquifex... 115 2e-24
sp|P42589|YGJH_ECOLI HYPOTHETICAL 12.3 KD PROTEIN IN ILEX-EBGR I... 101 2e-20
pir||H72655 protein secretion chaperonin APE0675 [similarity] - ... 99 2e-19
gb|AAF59019.1| (AE003835) CG8235 gene product [Drosophila melano... 96 1e-18
pir||F82090 methionyl-tRNA synthetase-related protein VC2336 [im... 94 4e-18
gb|AAK40936.1| Methionyl-tRNA synthetase N-term homolog (metS-li... 92 2e-17
emb|CAB57675.1| (Y18930) homolog of methionyl-tRNA synthetase [S... 92 2e-17
gi|4507947 tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase; tyr... 92 3e-17
gb|AAB95207.1| (AF021800) multisynthetase complex auxiliary comp... 92 3e-17
gi|11423982 tyrosyl-tRNA synthetase [Homo sapiens] 92 3e-17
gb|AAC82467.1| (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRN... 91 5e-17
gi|6679639 endothelial monocyte activating polypeptide 2 [Mus mu... 88 3e-16
gi|4758266 small inducible cytokine subfamily E, member 1; endot... 88 4e-16
pir||B55053 endothelial monocyte-activating protein II precursor... 88 4e-16
gb|AAF49462.1| (AE003527) CG4561 gene product [Drosophila melano... 88 4e-16
gi|11435649 small inducible cytokine subfamily E, member 1 [Homo... 88 4e-16
gi|6321333 G4 nucleic acid binding protein, involved in tRNA ami... 86 1e-15
gb|AAC49072.1| (U31348) G4p1 [Saccharomyces cerevisiae] 85 3e-15
pdb|1EUJ|A Chain A, A Novel Anti-Tumor Cytokine Contains A Rna-B... 85 3e-15
pir||I40248 methionyl tRNA synthetase - Lyme disease spirochete ... 83 1e-14
sp|P57519|SYL_BUCAI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 82 2e-14
sp|P43827|SYL_HAEIN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 82 2e-14
sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 82 3e-14
emb|CAA10534.1| (AJ131940) aminoacyl-tRNA synthetase cofactor [E... 82 3e-14
sp|O66680|SYLA_AQUAE LEUCYL-TRNA SYNTHETASE ALPHA SUBUNIT (LEUCI... 80 7e-14
gb|AAD32818.1|AC007660_19 (AC007660) putative methionyl-tRNA syn... 79 2e-13
emb|CAC12407.1| (AL445067) fragment of probable methionine--tRNA... 79 2e-13
pir||A64379 isoleucine--tRNA ligase (EC 6.1.1.5) - Methanococcus... 79 2e-13
sp|Q58050|SYL_METJA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 79 2e-13
pir||G82260 leucyl-tRNA synthetase VC0956 [imported] - Vibrio ch... 79 2e-13
pir||T47822 hypothetical protein F24G16.250 - Arabidopsis thalia... 78 3e-13
sp|Q9ZJ63|SYL_HELPJ LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 77 6e-13
pir||H75156 methionine--tRNA ligase truncated homolog PAB0278 [i... 76 1e-12
emb|CAA75164.1| (Y14947) endothelial-monocyte-activating polypep... 76 2e-12
sp|O83595|SYL_TREPA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 74 5e-12
gb|AAG20349.1| (AE005108) leucine-tRNA synthetase; LeuS [Halobac... 73 9e-12
sp|P36430|SYL_BACSU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 73 1e-11
pir||A41882 leucine--tRNA ligase (EC 6.1.1.4) - Bacillus subtili... 72 2e-11
pir||F71453 methionine--tRNA ligase truncated homolog PH0285 [im... 72 2e-11
emb|CAB90791.1| (AL355652) putative Cofactor for methionyl-and g... 72 3e-11
dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halo... 70 8e-11
>pir||B75074 methionyl-tRNA synthetase (mets) PAB2364 - Pyrococcus abyssi
(strain Orsay) >gi|5458407|emb|CAB49895.1| (AJ248286)
methionyl-tRNA synthetase (metS) [Pyrococcus abyssi]
Length = 722
Score = 1499 bits (3838), Expect = 0.0
Identities = 722/722 (100%), Positives = 722/722 (100%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA
Sbjct: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK
Sbjct: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI
Sbjct: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
SFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP
Sbjct: 181 SFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI
Sbjct: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD
Sbjct: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
Query: 361 VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP
Sbjct: 361 VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK
Sbjct: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
Query: 481 EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHKVRK 540
EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHKVRK
Sbjct: 481 EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHKVRK 540
Query: 541 PEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRR 600
PEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRR
Sbjct: 541 PEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRR 600
Query: 601 VYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLV 660
VYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLV
Sbjct: 601 VYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLV 660
Query: 661 AGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAK 720
AGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAK
Sbjct: 661 AGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAK 720
Query: 721 VR 722
VR
Sbjct: 721 VR 722
>sp|O58721|SYM_PYRHO METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437669|pir||D71091 methionine--tRNA ligase (EC
6.1.1.10) - Pyrococcus horikoshii
>gi|3257407|dbj|BAA30090.1| (AP000004) 723aa long
hypothetical methionyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 723
Score = 1410 bits (3609), Expect = 0.0
Identities = 663/723 (91%), Positives = 706/723 (96%), Gaps = 1/723 (0%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA
Sbjct: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
LKEGRSPREIVDEFHE IKITFQRAKISFDFFGRTELPIHYKLSQ+FFLKAYENGHLVKK
Sbjct: 61 LKEGRSPREIVDEFHEHIKITFQRAKISFDFFGRTELPIHYKLSQQFFLKAYENGHLVKK 120
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
VTKQAYCEHDKMFLPDRFVIGTCP+CGAE+Q+GDQCEVCGRPLTPEILINPRCA+CGRPI
Sbjct: 121 VTKQAYCEHDKMFLPDRFVIGTCPFCGAENQRGDQCEVCGRPLTPEILINPRCALCGRPI 180
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
SFR+SAHYYIKMQDFAE+LKRWIE QPWKPNVKNMVL WIEEGLEERAITRDLNWGIPVP
Sbjct: 181 SFRESAHYYIKMQDFAEKLKRWIENQPWKPNVKNMVLKWIEEGLEERAITRDLNWGIPVP 240
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
LDEEDMK KVLYVWFEAPIGYISIT+E+FKR+GKPNEWKKYWLNID +TRVIHFIGKDNI
Sbjct: 241 LDEEDMKNKVLYVWFEAPIGYISITMEYFKRLGKPNEWKKYWLNIDSETRVIHFIGKDNI 300
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD
Sbjct: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
Query: 361 VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
VFPADYLRYYLTTIMPETRDSDFSF++FK RINEELVNNLGNFVHRA+TFVNRYFDG+VP
Sbjct: 361 VFPADYLRYYLTTIMPETRDSDFSFAEFKTRINEELVNNLGNFVHRAMTFVNRYFDGIVP 420
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
ERGELDELDR+ALEEIEKAF+EVGELIMNYRFKDALKRVM LASFGN+YFDHKQPWKTAK
Sbjct: 421 ERGELDELDRQALEEIEKAFEEVGELIMNYRFKDALKRVMELASFGNKYFDHKQPWKTAK 480
Query: 481 EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHKVRK 540
ED+ RTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVK+W+F+ELPAGH+VRK
Sbjct: 481 EDRARTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKKWKFKELPAGHRVRK 540
Query: 541 PEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRR 600
EILFKKVTD+QIIYFILNYM + NPEGA++LL+KYYKREDVI+VAKEKFG+E++++L+R
Sbjct: 541 AEILFKKVTDEQIIYFILNYMGRNNPEGAKMLLEKYYKREDVIKVAKEKFGEESKIILKR 600
Query: 601 VYKDIKLKEKKEGKEM-YVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTL 659
+YKDIKL+E KE KEM YVKF+DFAKLDLRVGKIIEVKDHPNADKLY+VKVDLG EVRTL
Sbjct: 601 IYKDIKLEEGKEEKEMEYVKFEDFAKLDLRVGKIIEVKDHPNADKLYIVKVDLGKEVRTL 660
Query: 660 VAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGA 719
VAGLKKYYKPEELLN+YV++VANLEPKKLRG+ SQGMLLAADDGE VALLMPDKEVKLGA
Sbjct: 661 VAGLKKYYKPEELLNKYVIIVANLEPKKLRGVESQGMLLAADDGENVALLMPDKEVKLGA 720
Query: 720 KVR 722
KVR
Sbjct: 721 KVR 723
>sp|O26687|SYM_METTH METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437664|pir||G69177 methionine--tRNA ligase (EC
6.1.1.10) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621666|gb|AAB85093.1| (AE000841)
methionyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 651
Score = 598 bits (1524), Expect = e-169
Identities = 308/722 (42%), Positives = 432/722 (59%), Gaps = 71/722 (9%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M + +T ALPYANGP H GHL Y+PADI+ RY RL+G+DV+F+C TDEHGTPI+ +A
Sbjct: 1 MSKVFITCALPYANGPTHLGHLRSTYIPADIYARYRRLRGDDVLFVCATDEHGTPIAVKA 60
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
EGR+P E+ +HE I+ +R ISFD F RT +H++++Q+FFLK YE G + +K
Sbjct: 61 EAEGRTPLEVATRYHEMIRGDLERCDISFDSFTRTTDELHHEIAQKFFLKLYEKGFIYEK 120
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
KQ YC + FLPDR+V GTCPYCG+E +GD CE CGR L P L +PRC +CG
Sbjct: 121 DIKQLYCGDCQRFLPDRYVEGTCPYCGSEGARGDHCEGCGRHLEPLQLEDPRCMVCGSEP 180
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
RDS HY+ ++ F + ++ WIE NV+N + W+ EGL++ +TRD+ WG+ VP
Sbjct: 181 EVRDSRHYFFRLNQFQDEIREWIEGSEMPSNVRNYAIQWLREGLKDWILTRDMEWGVQVP 240
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
L E +GK++YVW EA +GYIS K+ G+ +W++YW + IHFIGKD I
Sbjct: 241 L--EGNEGKIIYVWGEAFLGYISSAAAWSKKTGR--DWREYW-----DSGAIHFIGKDII 291
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
HAIFWPA LMAYG P +I A EYL+LEG+K STS+NW +W +FL+
Sbjct: 292 YHHAIFWPALLMAYG----------CRTPANIIAGEYLSLEGQKMSTSKNWVVWTSDFLE 341
Query: 361 VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
F D LRYYLT P TRD+DFS+ DF+ R+N+EL + LGNF+HR +F R+FDG VP
Sbjct: 342 RFDRDLLRYYLTVNAPLTRDTDFSWDDFQRRVNDELADVLGNFLHRTFSFTGRFFDGRVP 401
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
GEL D E LE I A V EL+ ++F+DAL ++ LA GN+YF+ ++PWK K
Sbjct: 402 AAGELTAEDLEFLESIRAAHDTVAELLDKFQFRDALMHIIKLAKRGNKYFNDQEPWKAVK 461
Query: 481 EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHKVRK 540
E R T +++ + LG LL PF+P A+ +I ++NL++ + W F EL G + +
Sbjct: 462 ESPARASTCLHLCNLLAANLGKLLRPFMPSAAGRILSIMNLED-EAWGFHELREGQVIER 520
Query: 541 PEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRR 600
+ LF K+TD+ I E A+++ ED DE E
Sbjct: 521 AKPLFSKITDEAI-----------EEEKAKLI------EED----------DEVET---- 549
Query: 601 VYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLV 660
V DDF +D+RVG I + +DKL + +D+G+ +V
Sbjct: 550 -----------------VTIDDFTTMDIRVGVIRSAERIEGSDKLLKLIIDVGEREMQVV 592
Query: 661 AGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAK 720
AGL + Y PE+L+ R + V+ NL+P KL G+ S+GM+LA GE + +L P + ++G +
Sbjct: 593 AGLAEKYSPEDLVERKITVLVNLKPAKLFGVKSEGMVLAT--GESLNILDPG-DAEVGER 649
Query: 721 VR 722
+R
Sbjct: 650 IR 651
>sp|Q58659|SYM_METJA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|2129107|pir||F64457 methionine--tRNA ligase (EC
6.1.1.10) - Methanococcus jannaschii
>gi|1591898|gb|AAB99269.1| (U67567) methionyl-tRNA
synthetase (metS) [Methanococcus jannaschii]
Length = 651
Score = 564 bits (1439), Expect = e-160
Identities = 305/725 (42%), Positives = 440/725 (60%), Gaps = 78/725 (10%)
Query: 2 VRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
+RY++T+AL Y NGP+H GH Y+PADI +YL+L+GEDV+ + GTD HG PI+ A
Sbjct: 1 MRYLITTALAYTNGPLHLGHARSTYIPADIIYKYLKLRGEDVIHVGGTDNHGVPITLTAE 60
Query: 62 KEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKV 121
KEG+SP EIV+++H +IK + FD FG+T IH + +QEF+LK ENG++ +K
Sbjct: 61 KEGKSPEEIVEKYHNEIKEDLDLLGVEFDAFGKTHSQIHIETAQEFYLKLKENGYIYEKE 120
Query: 122 TKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPIS 181
+Q YC + K FLPDR+V G CPYCG E +GD CEVCGR L P L +P C IC
Sbjct: 121 IEQFYCPNCKKFLPDRYVEGICPYCGGE-ARGDHCEVCGRHLEPFELKDPYCVICKGKPE 179
Query: 182 FRDSAHYYIKMQDFAERLKRWIEKQPWKP-NVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
R + H++ K+ + L+ +I+ P +VKNM L+WI+E L + I+RD++WG+P+P
Sbjct: 180 IRKTKHHFFKLSALKKELEEYIKNAKEMPEHVKNMALNWIKE-LHDWDISRDISWGVPIP 238
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
+V+YVW EAPIGYIS T K +G+ WKKYWL D T++ HFIGKD
Sbjct: 239 -----GTNQVMYVWLEAPIGYISFT----KMLGE--IWKKYWLEKD--TKIYHFIGKDIT 285
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
HA+FWP L+A+G + NLP + + YLTLEG+K STS+ W +WV +F+
Sbjct: 286 VHHAVFWPGMLIAHGSF---------NLPTAVVSGGYLTLEGRKMSTSKRWVVWVKDFVK 336
Query: 361 VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV-V 419
F ADYLRYYL P +D DFSF DFK +IN EL+N +GNF HR LTF +R F V +
Sbjct: 337 NFDADYLRYYLIMSAPLFKDCDFSFDDFKNKINNELINIIGNFTHRVLTFTHRKFKKVPI 396
Query: 420 PERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTA 479
+ L E D+E L++ E+ + V + I +++F+DAL ++ LA GN YF +PW A
Sbjct: 397 VDEDRLKEEDKELLKKCEETLEAVDKNIRSFKFRDALVNILHLAIEGNSYFQKMEPW--A 454
Query: 480 KEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHKVR 539
+D+ R + + VK L LL P++P S + L+N E E R G++++
Sbjct: 455 VDDEERLKEILYTCCKTVKTLVYLLYPYMPKKSLALLELMN--EELDLELR----GNELK 508
Query: 540 KPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLR 599
KP+I+FKK+ + +I E + +
Sbjct: 509 KPKIIFKKIDNKKI-----------------------------------------EEMKK 527
Query: 600 RVYKDIKLKEKKEGKEM-YVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRT 658
++Y++ K +E K G++M + K+DLRVG+++E +D P + KL + VDLGDE R
Sbjct: 528 KLYEN-KKEETKGGEKMEQIDISYLEKIDLRVGEVVEAEDIPKSKKLLKLMVDLGDEKRQ 586
Query: 659 LVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGE-RVALLMPDKEVKL 717
+V+G+K YYKPE+L+ + V+V+ NL+P KL G+ S+GM+LAA+D E V+LL DK++K
Sbjct: 587 IVSGIKGYYKPEDLVGKKVIVICNLKPAKLCGVLSEGMILAAEDDEGNVSLLTVDKDIKA 646
Query: 718 GAKVR 722
G+KVR
Sbjct: 647 GSKVR 651
>emb|CAC12287.1| (AL445066) probable methionyl-tRNA synthetase [Thermoplasma
acidophilum]
Length = 547
Score = 482 bits (1227), Expect = e-135
Identities = 239/556 (42%), Positives = 351/556 (62%), Gaps = 20/556 (3%)
Query: 2 VRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
++ +V ALPYANGP+H GH+AGAYL AD+FVRY RL G V+++ G+DE+GTPI+ RA
Sbjct: 4 IKILVNCALPYANGPLHIGHIAGAYLGADVFVRYNRLMGNQVLYVSGSDEYGTPITVRAE 63
Query: 62 KEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKV 121
KEGRSP+EI D ++E+ TF+ ISFD F RT P H + +Q+FF+K G++ K
Sbjct: 64 KEGRSPKEIADIYYEEHLRTFENLGISFDIFMRTTWPEHSENAQDFFIKLLNEGYIEKGT 123
Query: 122 TKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPIS 181
+C F+PDR++ GTCPYC +GDQC+ CGR L P+ LI+P+C + G
Sbjct: 124 MIAPFCRKIGRFMPDRYIEGTCPYCHYPKARGDQCDNCGRTLDPQDLIDPKCILSGETPE 183
Query: 182 FRDSAHYYIKMQDFAERLKRWI-EKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
FR++ H+++++ +RLK WI K WKPNV ++I GL++R ITRD++WG+ +P
Sbjct: 184 FRETEHFFLRLDLLEDRLKSWISSKNFWKPNVLAYTQNFISGGLKKRPITRDIDWGVKIP 243
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
LD D K +YVWFEA IGYI+ E+ KR G P+ WK+Y++ D + R +FIGKDNI
Sbjct: 244 LDGYD--SKRIYVWFEALIGYITGAKEYSKRTGNPDLWKEYYM--DPEVRNYYFIGKDNI 299
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFHAI WPA LM YG + NLPYDIPANEYLT +G++FS SR V + L
Sbjct: 300 PFHAIIWPAMLMGYGGF---------NLPYDIPANEYLTFKGQQFSKSRGIGYSVDDLLK 350
Query: 361 VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
PADYLRYY+ +I+PET DSDFS + +N +L++ GN V+R L+F++RY + P
Sbjct: 351 AVPADYLRYYVASILPETGDSDFSLEELVNTVNSDLIDKYGNLVYRILSFMDRY--SINP 408
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
+ +D E + +++F+ E + K L R + LA + N +F+ +PWKT K
Sbjct: 409 D--PVDVSGDEEFKYAQRSFELWSEDLSGVHVKRGLLRWLDLAIYANGFFNRSEPWKTIK 466
Query: 481 EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGH--KV 538
D+ + + +SL+I + L +++ P++P ++EKIW++L + +R L H V
Sbjct: 467 NDRQKLNHDLYLSLKITEVLTVMVYPYIPSSAEKIWNMLGIPFAIGQSYRHLYEMHAFSV 526
Query: 539 RKPEILFKKVTDDQII 554
+ I F+K+ + ++
Sbjct: 527 HRGAIPFEKIDLESLV 542
>gi|11499048 methionyl-tRNA synthetase (metS) [Archaeoglobus fulgidus]
>gi|3122911|sp|O28819|SYM_ARCFU METHIONYL-TRNA
SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437665|pir||D69431 methionine--tRNA ligase (EC
6.1.1.10) - Archaeoglobus fulgidus
>gi|2649118|gb|AAB89796.1| (AE001003) methionyl-tRNA
synthetase (metS) [Archaeoglobus fulgidus]
Length = 658
Score = 474 bits (1207), Expect = e-132
Identities = 266/722 (36%), Positives = 401/722 (54%), Gaps = 72/722 (9%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
+VT LPYANG H GHL Y+PAD++VRYLR+ GE+VVF+CG+D HGTPI A ++G
Sbjct: 3 LVTCGLPYANGKAHVGHLR-TYVPADVYVRYLRMSGEEVVFVCGSDCHGTPIVVNAEQQG 61
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
SP+E+VD +HE F I FDF+GRT+ H+ + E + E G++ K +
Sbjct: 62 LSPKELVDIYHEHFIKIFDALNIKFDFYGRTDSDYHHHRTTEIVKRLIEKGYVYPKEIQL 121
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEV-CGRPLTPEILINPRCAICGRPISFR 183
AYC + FLPDR+V G CPYCGA +GD+C+ CGR L P + PRC ICG FR
Sbjct: 122 AYCPKCQRFLPDRYVEGICPYCGAL-ARGDECDQGCGRHLEPGEIKEPRCKICGSKAEFR 180
Query: 184 DSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVPLDE 243
HY+ K+ +F + L+ ++ K N N +W+ + L + ITR+L WG+ P +
Sbjct: 181 SQRHYFFKLTEFQDFLEDYLSKLKGTENALNYARNWV-KNLRDWCITRNLEWGVRFPGE- 238
Query: 244 EDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPFH 303
V+YVW +APIGYIS T + + K +W+K W IDG +IHFIG D + H
Sbjct: 239 ---PNLVVYVWVDAPIGYISFTEKACEE--KGCDWRKIW--IDGDAEIIHFIGLDIVYHH 291
Query: 304 AIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHE--FLDV 361
IFWPA L A++ LP + A+ + +EGK FS SR + +WV E
Sbjct: 292 CIFWPAMLKG----------ADYALPSAVVASGMVKVEGKTFSKSRGYVVWVEEDYLKSG 341
Query: 362 FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVPE 421
DYLRYY+ +D +FS+ F+ ++N E++ LGNF++R L F + F V
Sbjct: 342 LSPDYLRYYIVNYTSHQKDLNFSWEVFREKVNNEVIATLGNFLYRVLLFAWKNFGEV--- 398
Query: 422 RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAKE 481
++ +D E LE+I + +++ + + FK A M LA++GN YF + +PW+ K
Sbjct: 399 --RMEGVDEEVLEKIRETEQKILSALEEWEFKAASDAFMELATYGNVYFQNAKPWELIKT 456
Query: 482 DKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLD--EVKRWEFRELPAGHKVR 539
DK V LQ+ KAL I P +P++ E++ + LD V+ + ++ K+
Sbjct: 457 DKEAARRAVASCLQLAKALIIFAYPVMPESMERMAKAIGLDLENVRLSDAYKVDEVMKLS 516
Query: 540 KPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLR 599
KPE+ F KV D+ I E + +V +++F E E
Sbjct: 517 KPEVPFAKVEDEVI--------------------------EKLQKVMEKRFRGEGE---- 546
Query: 600 RVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTL 659
K+++K+E + +DF KLD+R+G++++ + + KL + +D+GDE R +
Sbjct: 547 ------KMEQKEE-----ISIEDFQKLDIRIGRVLKAEKVKKSKKLIKLIIDIGDEQRQI 595
Query: 660 VAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGA 719
V+G+ + Y PEEL + VVV+ANL+P K G+ S+GM+LAA+ + LL P+KEV+ G
Sbjct: 596 VSGIAEDYTPEELEGKLVVVLANLKPAKFMGVESRGMILAAEKDGKAVLLTPEKEVEPGT 655
Query: 720 KV 721
+V
Sbjct: 656 RV 657
>pir||T05247 methionine--tRNA ligase homolog F18A5.170 - Arabidopsis thaliana
>gi|4455307|emb|CAB36842.1| (AL035528) methionyl-tRNA
synthetase-like protein [Arabidopsis thaliana]
>gi|7268082|emb|CAB78420.1| (AL161537) methionyl-tRNA
synthetase-like protein [Arabidopsis thaliana]
Length = 797
Score = 474 bits (1206), Expect = e-132
Identities = 278/751 (37%), Positives = 408/751 (54%), Gaps = 67/751 (8%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++TSALPY N H G++ G L AD++ RY RL+G + ++ICGTDE+GT +AL+E
Sbjct: 20 LITSALPYVNNVPHLGNIIGCVLSADVYARYCRLRGYNAIYICGTDEYGTATETKALEEN 79
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
+P+EI D++H K + ISFD FGRT P ++ Q F K ++N L + +Q
Sbjct: 80 CTPKEICDKYHAIHKEVYDWFGISFDKFGRTSTPEQTEVCQAIFNKLWDNKWLSENTMQQ 139
Query: 125 AYCEHDKMFLPDRFVIGTCPY--CGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
YC+ K FL DR V G+CP+ C + +GDQCE CG+ L P L +P+C +C
Sbjct: 140 LYCDTCKKFLADRLVEGSCPFEGCNYDSARGDQCEKCGKLLNPTELKDPKCKVCQNTPRI 199
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQ----PWKPNVKNMVLSWIEEGLEERAITRDLNWGIP 238
RD+ H +I++ +RL+ +I+K W N +W+ +GL +R ITRDL WG+P
Sbjct: 200 RDTDHLFIELPLLKDRLEAYIKKTSVTGSWSQNAIQTTNAWLRDGLRQRCITRDLKWGVP 259
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKD 298
VP E K KV YVWF+APIGY+SIT + +EW+K+W N + + F+GKD
Sbjct: 260 VP--HEKYKDKVFYVWFDAPIGYVSITSCY------TSEWEKWWKNPE-NVELYQFMGKD 310
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
N+PFH + +P+ + E W L I EYL E KFS S+ ++ ++
Sbjct: 311 NVPFHTVMFPSTQLG--------TEENWTLMKTISVTEYLNYEDGKFSKSKGVGVFGNDV 362
Query: 359 LDV-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFV----NR 413
D P + RYYL T PE D+ FS++D + ++N EL++NLGNFV+R L+F+ N
Sbjct: 363 KDTNIPVEVWRYYLLTNRPEVSDTSFSWTDLQAKLNGELLSNLGNFVNRVLSFIAKPDNA 422
Query: 414 YFDGVVPER--GELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFD 471
+ V+P+ E L + E++EK E E + + K LK M ++S GN Y
Sbjct: 423 GYGSVIPDAHDAESHSLTKSLAEKVEKFVAEYVEAMEKVKLKQGLKTAMLISSEGNYYLQ 482
Query: 472 HKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNL-------DE- 523
Q WK KEDK + + +V L LLEPF+P S +++ LNL DE
Sbjct: 483 ASQFWKLYKEDKPLCAVVIRTAAGLVHLLAQLLEPFMPSFSCEVFKQLNLPPQFSLSDER 542
Query: 524 ------VKRWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYY 577
+ W+ LP H++ P+ LFK++ +D++ + + + AR D+
Sbjct: 543 GEVLLASRPWDI--LPPSHRIGTPQPLFKELENDEVARYREKFAGSQSDRRAR---DEAA 597
Query: 578 KREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDD----FAKLDLRVGKI 633
D ++ K K D K K K GK D A+LD+RVGKI
Sbjct: 598 NLAD--QLNKTKLSDA---------KKQKASSKGGGKPKPQPAADREITMARLDIRVGKI 646
Query: 634 IEVKDHPNADKLYVVKVDL-GDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIG 692
++ + HP AD LYV ++D+ G E+RT+V+GL KY EE+ NR V V+ NL+P K+R I
Sbjct: 647 VKAEKHPKADALYVEEIDVGGGEIRTVVSGLVKYIPLEEMQNRMVCVLCNLKPAKMRDIV 706
Query: 693 SQGMLLAA--DDGERVALLMPDKEVKLGAKV 721
SQ M+LAA DG +V L+ P K +G +V
Sbjct: 707 SQAMVLAASSSDGSKVELVEPPKTANIGERV 737
>sp|Q9YCY3|SYM_AERPE METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7521196|pir||B72714 probable methionyl-tRNA
synthetase APE1129 - Aeropyrum pernix (strain K1)
>gi|5104799|dbj|BAA80114.1| (AP000060) 572aa long
hypothetical methionyl-tRNA synthetase [Aeropyrum
pernix]
Length = 572
Score = 467 bits (1189), Expect = e-130
Identities = 241/563 (42%), Positives = 343/563 (60%), Gaps = 29/563 (5%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M +Y+VTSA PY N H G L G+ L ADI+ RYLRL+G VVF+ G+DEHGTPI A
Sbjct: 1 MAKYVVTSAWPYVNHVPHLGTLIGSVLSADIYARYLRLRGRQVVFVSGSDEHGTPIELEA 60
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
K+G P+E+ D+ HE ++ +ISFD + RTE P+H + EF K ENG++ +
Sbjct: 61 RKKGVHPKELTDQVHEYDVKMWREYRISFDNYSRTESPVHKEFVMEFMKKLEENGYIFSQ 120
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
YCE DK+FLPDRFV GTCPYCG E +GDQC+ CGR L P L NPRCA+CG
Sbjct: 121 EEVLPYCERDKIFLPDRFVEGTCPYCGYEKARGDQCDECGRLLHPTELKNPRCALCGSKP 180
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQ-PWKPNVKNMVLSWIEEGLEERAITRDLNWGIPV 239
++ + H++I ++ +RL +W+E + +VK ++W+ +GL+ R++TRDL+WG+P
Sbjct: 181 VYKSTRHWFIDLRRVQDRLLKWLESHGELQDSVKKYSINWVAQGLKPRSVTRDLSWGVPA 240
Query: 240 PLDEEDMKGKVLYVWFEAPIGYISITIEHF-KRIGKPNEWKKYWLNIDGQTRVIHFIGKD 298
P + +GK +YVWF+A +GY+S T E F R G P EWK +W D TR ++FIGKD
Sbjct: 241 PF--KGAEGKTIYVWFDALLGYVSATKELFIMRRGDPEEWKSWWW--DSGTRTVYFIGKD 296
Query: 299 NIPFHAIFWPA-FLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHE 357
NIPFHAI PA FL ++ Y LP+ I A EYL EG++FS SR +W+ E
Sbjct: 297 NIPFHAIILPALFLASHDPYV---------LPWRISATEYLMYEGQQFSKSRRIGVWIDE 347
Query: 358 FLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
L++ PADY R+ L + PE RD++F++ +F +N EL +++GNFV+R L+ V G
Sbjct: 348 ALEIAPADYWRWALARMRPEARDTNFTWKEFYRIVNTELNDDIGNFVNRVLSLVRSRMSG 407
Query: 418 VVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
V PE +L E + +E + +A V E + R K A + ++ +A GN Y + QPWK
Sbjct: 408 VAPEPEDLGE-HQGFVERVRRAAWAVAEDLEAIRIKRATEGILEIAREGNAYLNRTQPWK 466
Query: 478 TAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNL---------DEVKRWE 528
+D+ ++ +L VK L LL PF PDA++++W +L L DE W
Sbjct: 467 LLSQDREEGVRALSAALYAVKTLAHLLAPFTPDAADRLWSMLGLAGSVHEAVWDE---WL 523
Query: 529 FRELPAGHKVRKPEILFKKVTDD 551
R LP G ++ + E LF+K+ DD
Sbjct: 524 DRPLPGGARIVRVEPLFQKLPDD 546
>gb|AAC99620.1| (AF040700) methionyl-tRNA synthetase [Oryza sativa]
Length = 804
Score = 462 bits (1175), Expect = e-129
Identities = 270/751 (35%), Positives = 406/751 (53%), Gaps = 62/751 (8%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
+VTSALPY N H G++ G L AD+F RY RL+G +V++ICGTDE+GT +A++E
Sbjct: 22 LVTSALPYVNNVPHLGNIIGCVLSADVFARYCRLRGYNVIYICGTDEYGTATETKAMEEK 81
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
SP+EI D++H ++ I FD FGRT P ++ Q F K EN L + +Q
Sbjct: 82 CSPKEICDKYHAVHSEVYKWFDIKFDKFGRTSSPQQTEVCQAIFQKLMENNWLTENTMQQ 141
Query: 125 AYCEHDKMFLPDRFVIGTCPY--CGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
YC+ + FL DR V G CP C E +GDQCE C + L P LI+P+C +C
Sbjct: 142 LYCDTCQRFLADRLVEGKCPTEGCNYEAARGDQCENCSKLLNPTELIDPKCKVCKNTPRV 201
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQP----WKPNVKNMVLSWIEEGLEERAITRDLNWGIP 238
RD+ H ++++ +++L +I + W N +W++EGL+ R ITRDL WG+P
Sbjct: 202 RDTDHLFLELPLLSDKLVNYINETSVAGMWSQNAIQATNAWLKEGLKPRCITRDLKWGVP 261
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKD 298
VP E K KV YVWF+APIGY+SIT + +W+K+W + D + F+GKD
Sbjct: 262 VP--HEKYKDKVFYVWFDAPIGYVSITASY------TPDWEKWWKDPD-NVELFQFMGKD 312
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
N+PFH + +P+ L+ G+ +W + I EYL E KFS S ++ ++
Sbjct: 313 NVPFHTVMFPSTLLGTGE--------KWTMMKTISVTEYLNYEAGKFSKSHGIGVFGNDA 364
Query: 359 LDV-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNR---- 413
D P + RYYL T PE D+ F+++D + ++N EL+NNLGNF++R L+FV +
Sbjct: 365 KDTNIPPEVWRYYLLTNRPEVSDTLFTWADLQAKLNSELLNNLGNFINRVLSFVAKPAGA 424
Query: 414 YFDGVVPE--RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFD 471
+D +VP+ E L + E+ K ++ E + + K LK M ++S GN Y
Sbjct: 425 GYDSIVPDAPNAESHPLTKALAEKTNKWVEQYLEAMEKVKLKQGLKSAMGISSDGNAYLQ 484
Query: 472 HKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLD--------- 522
Q WK KED + S+ +V L LLEPF+P S ++ LN+
Sbjct: 485 ESQFWKLYKEDPAACAVVMKTSVGVVYLLACLLEPFMPSFSNEVLLQLNMTPEESLSFCD 544
Query: 523 ------EVKR-WEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDK 575
+ KR W+F + AGHK+ KP LFK++ D+++ F + ++ D
Sbjct: 545 DKGEIAKAKRPWDF--VSAGHKIGKPSPLFKELKDEEVESFRNKFAGSQAERSSKAQADA 602
Query: 576 YYKR-EDVIRVAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFD-DFAKLDLRVGKI 633
K+ D ++ K G + K + K+ K + D AKLD+RVG I
Sbjct: 603 EAKKVADKLKGTKLSDGGQ---------KKEQKKQSGGSKSKNAEVDVTVAKLDIRVGLI 653
Query: 634 IEVKDHPNADKLYVVKVDLGDEV-RTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIG 692
+ + HP+AD LYV ++D+G+E RT+V+GL K+ EE+ NR V V+ NL+P +RGI
Sbjct: 654 RKAQKHPDADSLYVEEIDVGEEAPRTVVSGLVKFIPLEEMQNRKVCVLCNLKPVAMRGIK 713
Query: 693 SQGMLLAA--DDGERVALLMPDKEVKLGAKV 721
S M+LAA +D +V L+ P + +G +V
Sbjct: 714 SHAMVLAASNEDHTKVELVEPPESAAVGERV 744
>emb|CAB57741.1| (Y18930) methionyl-trna synthetase [Sulfolobus solfataricus]
Length = 573
Score = 444 bits (1131), Expect = e-123
Identities = 230/559 (41%), Positives = 342/559 (61%), Gaps = 26/559 (4%)
Query: 2 VRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLK--GEDVVFICGTDEHGTPISFR 59
++ +VT+A PY N H G+L G+ L AD+F RY RL+ E+V+F+ G+DEHGTPI
Sbjct: 1 MKVLVTAAWPYVNSVPHLGNLIGSILSADVFARYARLRYGKENVLFVSGSDEHGTPIEIE 60
Query: 60 ALKEGRSPREIVDEFHEQIKITFQRA-KISFDFFGRTELPIHYKLSQEFFLKAYENGHLV 118
A+K +P+E+ D+ HE + F KISFD + RTE IH K +EF LK + ++
Sbjct: 61 AIKRKVNPKELTDQAHEYDRHLFLNVWKISFDNYTRTESEIHKKFVREFLLKLTK--YIK 118
Query: 119 KKVTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGR 178
+ YCE+DK++LPDRFV GTCPYCG ED +GDQC+ CG+ LTP +L+NP+C+ICG+
Sbjct: 119 VSEDEIPYCENDKLYLPDRFVKGTCPYCGFEDARGDQCDNCGKLLTPSLLVNPKCSICGK 178
Query: 179 PISFRDSAHYYIKMQDFAERLKRWIEKQPWKP-NVKNMVLSWIEEGLEERAITRDLNWGI 237
F+ + H++ + +F ++++ WI P NVK++ LSW+ EGL+ R+ITRD WGI
Sbjct: 179 TPVFKKTKHWFFDLSEFNDKIRGWISSSNEMPDNVKSVALSWVGEGLKPRSITRDNKWGI 238
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
P P E + K +YVWFEA +GYIS IE+F+R G +WK+YW + +FIGK
Sbjct: 239 PAPF--EGAQDKSIYVWFEALLGYISAVIEYFERKGDQEKWKEYWFG--PNIKSYYFIGK 294
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHE 357
DNIPFHA+ PA LMA E E++LP I A EYL EG+KFS SR +W+ E
Sbjct: 295 DNIPFHAVILPAMLMA--------SEEEYHLPDVIAATEYLLYEGQKFSKSRKIGVWIDE 346
Query: 358 FLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
++ +Y R+ L + PE +D++F++ + +N EL +++GN+V+R L+ VNRY+ G
Sbjct: 347 APELMDVEYWRFVLIRLRPEEKDTNFTWRETVRIVNTELNDDIGNYVNRVLSMVNRYYSG 406
Query: 418 VVPE--RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQP 475
+VPE LD+ DR+ + I + K VG+L + K + ++ N Y + K P
Sbjct: 407 IVPEFKIDILDDNDRKIISLINETPKVVGDLFEKGKLKAGTEEMLKFVRECNAYLNMKAP 466
Query: 476 WKTAKEDK-VRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEV--KRWEFR-- 530
W K K + T+ I VK + ILL P +P ++KI+ +LN+ + ++W+
Sbjct: 467 WDLYKSGKEIELKNTLYIGTNSVKTIAILLYPLMPSHAQKIYEMLNMGNIENEKWDVAST 526
Query: 531 -ELPAGHKVRKPEILFKKV 548
+ GHK+ K +LFKK+
Sbjct: 527 LSVNPGHKIGKVNVLFKKL 545
>gb|AAK40875.1| Methionyl-tRNA synthetase (metS) [Sulfolobus solfataricus]
Length = 573
Score = 444 bits (1131), Expect = e-123
Identities = 230/559 (41%), Positives = 342/559 (61%), Gaps = 26/559 (4%)
Query: 2 VRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLK--GEDVVFICGTDEHGTPISFR 59
++ +VT+A PY N H G+L G+ L AD+F RY RL+ E+V+F+ G+DEHGTPI
Sbjct: 1 MKVLVTAAWPYVNSVPHLGNLIGSILSADVFARYARLRYGKENVLFVSGSDEHGTPIEIE 60
Query: 60 ALKEGRSPREIVDEFHEQIKITFQRA-KISFDFFGRTELPIHYKLSQEFFLKAYENGHLV 118
A+K +P+E+ D+ HE + F KISFD + RTE IH K +EF LK + ++
Sbjct: 61 AIKRKVNPKELTDQAHEYDRHLFLNVWKISFDNYTRTESEIHKKFVREFLLKLTK--YIK 118
Query: 119 KKVTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGR 178
+ YCE+DK++LPDRFV GTCPYCG ED +GDQC+ CG+ LTP +L+NP+C+ICG+
Sbjct: 119 VSEDEIPYCENDKLYLPDRFVKGTCPYCGFEDARGDQCDNCGKLLTPSLLVNPKCSICGK 178
Query: 179 PISFRDSAHYYIKMQDFAERLKRWIEKQPWKP-NVKNMVLSWIEEGLEERAITRDLNWGI 237
F+ + H++ + +F ++++ WI P NVK++ LSW+ EGL+ R+ITRD WGI
Sbjct: 179 TPVFKKTKHWFFDLSEFNDKIRGWISSSNEMPDNVKSVALSWVGEGLKPRSITRDNKWGI 238
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
P P E + K +YVWFEA +GYIS IE+F+R G +WK+YW + +FIGK
Sbjct: 239 PAPF--EGAQDKSIYVWFEALLGYISAVIEYFERKGDQEKWKEYWFG--PNIKSYYFIGK 294
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHE 357
DNIPFHA+ PA LMA E E++LP I A EYL EG+KFS SR +W+ E
Sbjct: 295 DNIPFHAVILPAMLMA--------SEEEYHLPDVIAATEYLLYEGQKFSKSRKIGVWIDE 346
Query: 358 FLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
++ +Y R+ L + PE +D++F++ + +N EL +++GN+V+R L+ VNRY+ G
Sbjct: 347 APELMDVEYWRFVLIRLRPEEKDTNFTWRETVRIVNTELNDDIGNYVNRVLSMVNRYYSG 406
Query: 418 VVPE--RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQP 475
+VPE LD+ DR+ + I + K VG+L + K + ++ N Y + K P
Sbjct: 407 IVPEFKIDILDDNDRKIISLINETPKVVGDLFEKGKLKAGTEEMLKFVRECNAYLNMKAP 466
Query: 476 WKTAKEDK-VRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEV--KRWEFR-- 530
W K K + T+ I VK + ILL P +P ++KI+ +LN+ + ++W+
Sbjct: 467 WDLYKSGKEIELKNTLYIGTNSVKTIAILLYPLMPSHAQKIYEMLNMGNIENEKWDVAST 526
Query: 531 -ELPAGHKVRKPEILFKKV 548
+ GHK+ K +LFKK+
Sbjct: 527 LSVNPGHKIGKVNVLFKKL 545
>gb|AAG18903.1| (AE004992) methionine-tRNA synthetase; MetS [Halobacterium sp.
NRC-1]
Length = 689
Score = 430 bits (1093), Expect = e-119
Identities = 260/724 (35%), Positives = 390/724 (52%), Gaps = 55/724 (7%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
+VT LPY G +H GHL Y+ D F R LR G++ VF+ GTD HGTPI+ +A++ G
Sbjct: 13 VVTCGLPYPTGDLHIGHLR-TYVSGDAFSRALRKLGQETVFVSGTDMHGTPIAVQAIEAG 71
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
P ++ E HEQ TF+ ++FD +G T+ + +L++EF +N H+ + +
Sbjct: 72 VGPLDLGLERHEQYADTFEEFSVAFDTYGHTDEETNVELTREFVGAWEDNDHVYETEIQV 131
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQC-EVCGRPLTPEILINPRCAICGRPISFR 183
AY +LPDR+V GTCPYCG E +GD+C E C R L P + P I G +
Sbjct: 132 AYDPDADQWLPDRYVEGTCPYCG-EHARGDECDEGCQRHLEPGEIEAPVSTITGNSAEYH 190
Query: 184 DSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVPLDE 243
+ AH ++++ DF E L+ +I + N KN WIE GLE+ ITRDL+WGI P +
Sbjct: 191 ERAHKFLRLSDFQEYLEGFINRMEGTNNAKNQPREWIEGGLEDFCITRDLDWGIDYPGEG 250
Query: 244 EDMKGKVLYVWFEAPIGYISITIEHFKRIGKPN-EWKKYWLNIDGQTRVIHFIGKDNIPF 302
D VLYVW +API Y++ T ++ +R+G +W W + DG+ +IH IG+D I
Sbjct: 251 GD--DLVLYVWVDAPIEYVAATKQYSERVGTEEFDWASVWKDGDGE--IIHVIGRDIIQH 306
Query: 303 HAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV- 361
H +FWP+ L A++ P + A ++ ++G+ STS+N AIW E+LD
Sbjct: 307 HTVFWPSMLAG----------ADYAEPRAVCATGFVNIDGRGLSTSKNRAIWAAEYLDAG 356
Query: 362 FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVPE 421
F D LRYYL T RD +FS+++F R+N EL + +GNF +RAL F NR FDG E
Sbjct: 357 FHPDLLRYYLATASGFERDVNFSWAEFAQRVNTELADAVGNFAYRALLFANRNFDGTPQE 416
Query: 422 RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAKE 481
D+++ EI +A + + + Y + A +R ++LA FGN Y H +PW
Sbjct: 417 VSLTDDVE----TEIAQAMDDYEDALNEYDLRTAGERAVALARFGNEYIQHNEPWNL--- 469
Query: 482 DKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLD----EVKRWEFRELPAGHK 537
D + +Q+VKA+ +LL+PFLP+ +E +W L D + + + P +
Sbjct: 470 DSEAAAPVMRDCVQLVKAVAVLLQPFLPEKTETLWAQLGEDGRVSDATIADCLQAPPA-E 528
Query: 538 VRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVV 597
+P LF+K+ DD++ AK I A + D +
Sbjct: 529 FGEPAELFEKIEDDRVTELDEALAAK-------------------IEAASSEDADGEGMA 569
Query: 598 LRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVR 657
I+L+ E + F++F LDLRVG+++E + AD L ++VD+G EVR
Sbjct: 570 DETADDGIELEPLAEDD---ISFEEFQALDLRVGEVVEAEGIEGADDLARLEVDIGHEVR 626
Query: 658 TLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKL 717
+VAG+K+ + + L VVVVAN+EP +L G+ S GM+LAA GE LL ++ +
Sbjct: 627 QIVAGIKQLHDLDALPGTRVVVVANMEPSELFGVESNGMVLAA--GEDADLLTTHEDSEP 684
Query: 718 GAKV 721
G KV
Sbjct: 685 GTKV 688
>sp|Q44951|SYM_BORBU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437660|pir||B70173 methionine--tRNA ligase (EC
6.1.1.10) (metG) - Lyme disease spirochete
>gi|2688510|gb|AAB91520.1| (AE001160) methionyl-tRNA
synthetase (metG) [Borrelia burgdorferi]
Length = 734
Score = 415 bits (1055), Expect = e-114
Identities = 243/705 (34%), Positives = 372/705 (52%), Gaps = 66/705 (9%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
+VT+ALPY N H G+L L AD F RY ++ G + +++CGTDE+GT +AL E
Sbjct: 6 LVTAALPYVNNIPHLGNLVQV-LSADAFARYSKMSGIETLYVCGTDEYGTATETKALIEN 64
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
+P E+ ++++E K ++ I FD FGRT H + Q FFL+ +NG++ ++ T+Q
Sbjct: 65 TTPLELCNKYYEIHKSIYKWFNIEFDIFGRTTNKNHQDIVQNFFLQLEKNGYIKERETEQ 124
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
YC D MFL DR+VIG CP C + KGDQC+ C + L P LINP+C IC +
Sbjct: 125 FYCNKDSMFLADRYVIGECPECQSM-AKGDQCDNCSKLLNPTDLINPKCIICKNKPILKK 183
Query: 185 SAHYYIKMQDFAERLKRWIE----KQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
+ H Y+ + +L++WI+ + W N M +++ +GL+ERAITRDL WGIPVP
Sbjct: 184 TNHLYLDLPKIKTKLEKWIKNPDTSKNWNTNALKMTKAFLRDGLKERAITRDLKWGIPVP 243
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
++ + KV YVWF+APIGYISIT K W+ +W N D Q ++ FIGKDNI
Sbjct: 244 --KKGFENKVFYVWFDAPIGYISITKNIIK------NWESWWKNND-QVNLVQFIGKDNI 294
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
FH I +P + E W + + ++EYL E KFS S I+ ++ +
Sbjct: 295 LFHTIIFPCIEIG--------SEENWTILNQLSSSEYLNYENLKFSKSEGTGIFGNDAIT 346
Query: 361 V-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVV 419
P+D R+Y+ PE D F + D R+N EL++N N V+R LTF ++F V+
Sbjct: 347 TGIPSDIWRFYIYYNRPEKSDFQFMWQDLMERVNTELIDNFSNLVNRVLTFQRKFFGDVI 406
Query: 420 PERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTA 479
E E+ + ++I + ++ L K ALK ++ ++S GN+ F +PWK
Sbjct: 407 ----ETIEIQNKFWKQITPKYNKILNLFKKTELKSALKEILKISSLGNKIFQDNEPWKRK 462
Query: 480 KEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAG-HKV 538
T ++ + +++ L IL+ PF+P+ S+KI + +G K+
Sbjct: 463 NNSPQETKELISNLIYLIRDLSILMMPFIPETSKKIQQFFGNSYQFSTKILGTKSGIKKI 522
Query: 539 RKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGD-EAEVV 597
EILF K+ +I L Y N K ++ + + +AKE+ + E V
Sbjct: 523 EFTEILFNKLEQKKINNLKLKYSGDKNM--------KENEQAENLPIAKEQPENLFREKV 574
Query: 598 LRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVR 657
L RV K K++ E K ++ I+++ D N DK
Sbjct: 575 LLRVVKINKIERNPEAKNLF---------------ILKLDDGTNKDK------------- 606
Query: 658 TLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADD 702
+V+GL+ YY EELL +++++V NL+P K RGI S+GML+AA+D
Sbjct: 607 QIVSGLEGYYTEEELLGKHIIIVDNLKPAKFRGIKSEGMLIAAED 651
>sp|O83776|SYM_TREPA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437668|pir||E71281 methionine--tRNA ligase (EC
6.1.1.10) (metG) - syphilis spirochete
>gi|3323103|gb|AAC65761.1| (AE001250) methionyl-tRNA
synthetase (metG) [Treponema pallidum]
Length = 811
Score = 403 bits (1024), Expect = e-111
Identities = 250/759 (32%), Positives = 380/759 (49%), Gaps = 89/759 (11%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M R ++T+ALPY N H G+L L AD+F R+ R++G F+CGTDE+GT RA
Sbjct: 1 MTRKLITAALPYVNNVPHLGNLIQG-LSADVFARFCRMRGYHTCFVCGTDEYGTASETRA 59
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
++G SP ++ +H + +Q +SFD+FGRT H +L+Q F G + +
Sbjct: 60 AEQGLSPAQLCAHYHALHRDIYQWFDLSFDYFGRTTSDAHTELTQALFRHLDARGFISEH 119
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
+ QAYC H FL DR++ GTCP+C + + DQCE CG L PE L+N RC CG
Sbjct: 120 ESAQAYCLHCARFLADRYLRGTCPHCRNAEARADQCEHCGVLLEPETLLNARCVSCGTAP 179
Query: 181 SFRDSAHYYIKMQDFAERLKRWI--EKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIP 238
FR + H Y+ + + + W W N M W+ GL+ERAITRDL WG+P
Sbjct: 180 EFRPTRHLYLNLPALEKAYRSWFCTTNHLWTKNAVRMTEGWLRTGLQERAITRDLRWGVP 239
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRI----------GKPNEWKKYWLNIDGQ 288
VP + + KV YVWF+AP+GYISIT + G +W+ +WL+
Sbjct: 240 VP--KAGFEQKVFYVWFDAPVGYISITKCGTEAASSQEGGGTDDGVKEKWQSWWLD-QQD 296
Query: 289 TRVIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTS 348
++ F+GKDNIPFH +F+P L+ G+ W + + A EYL EG KFS S
Sbjct: 297 VELVQFVGKDNIPFHTLFFPCMLIGSGQ--------RWTMLTRLSATEYLNYEGGKFSKS 348
Query: 349 RNWAIWVHEFLDV-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRA 407
++ + + P+D R+YL PE D+ F++ +F+ R+N EL+ NL N V+R
Sbjct: 349 LGVGVFGSDAKESGIPSDLWRFYLLYHRPEKSDAHFTWHEFQERVNSELIGNLCNLVNRT 408
Query: 408 LTFVNRYFDGVVPERGELDELDREALEE-------IEKAFKEVGELIMNYRFKDALKRVM 460
LTFV R + GVVP + + +EE + K + +L+ + ++A + V
Sbjct: 409 LTFVARTYGGVVPAQDGARSTRAQVMEETLALREAVRNTAKRMTDLMEQVQLREAFREVF 468
Query: 461 SLASFGNRYFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLN 520
+L++ N+ PWKT +D+ R + +++ + IL PFLP +++ L
Sbjct: 469 ALSARANKALQDGAPWKTRAQDRERADALMRELCYVIRDVLILAHPFLPWYTQQAARFLG 528
Query: 521 L-------------------------DEVK---RW-EFRELPAGHKVRKPEILFKKVTDD 551
+ D V+ RW + E +V P ILF+ + +
Sbjct: 529 VQLSSCAPEGGGAVCAAKKDADTAQPDTVQPTLRWSDVGERKGLTQVHPPVILFRPLETE 588
Query: 552 QIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEKK 611
I + Y +GA + V R A+ G K+ ++KK
Sbjct: 589 TIAAYRARYAGTAR-DGAGV---------SVPRTAQMPTGMNK--------KETDAQQKK 630
Query: 612 EGKEMYVKFDDFAKLD--------LRVGKIIEVKDHPNADKLYVVKVDLGDEV-RTLVAG 662
E +EM D A+L L+V ++++V+ HPNAD L+V +D G V R +V+G
Sbjct: 631 EEREMPPP-SDTARLSAFFSERVVLKVARVLQVERHPNADMLFVETLDDGSGVERVIVSG 689
Query: 663 LKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAAD 701
L Y + L +V++V NL+P+ LRG+ S GMLLAA+
Sbjct: 690 LVPYMAADALRGAHVLIVDNLQPRSLRGVRSCGMLLAAE 728
>dbj|BAA95668.1| (D84224) methionyl tRNA synthetase [Homo sapiens]
Length = 900
Score = 399 bits (1013), Expect = e-110
Identities = 224/642 (34%), Positives = 351/642 (53%), Gaps = 51/642 (7%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++TSALPY N H G++ G L AD+F RY RL+ + +++CGTDE+GT +AL+EG
Sbjct: 267 LITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEEG 326
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
+P+EI D++H ++ ISFD FGRT P K++Q+ F + + G +++ +Q
Sbjct: 327 LTPQEICDKYHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQDTVEQ 386
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
CEH FL DRFV G CP+CG E+ +GDQC+ CG+ + L P+C +C +
Sbjct: 387 LRCEHCARFLADRFVEGVCPFCGYEEARGDQCDKCGKLINAVELKKPQCKVCRSCPVVQS 446
Query: 185 SAHYYIKMQDFAERLKRWIEK----QPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
S H ++ + +RL+ W+ + W PN + + SW+ +GL+ R ITRDL WG PVP
Sbjct: 447 SQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQFITRSWLRDGLKPRCITRDLKWGTPVP 506
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
L E + KV YVWF+A IGY+SIT + ++W+++W N + Q + F+ KDN+
Sbjct: 507 L--EGFEDKVFYVWFDATIGYLSITANY------TDQWERWWKNPE-QVDLYQFMAKDNV 557
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFH++ +P + E + L + A EYL E KFS SR ++ D
Sbjct: 558 PFHSLVFPCSALG--------AEDNYTLVSHLIATEYLNYEDGKFSKSRGVGVFGDMAQD 609
Query: 361 V-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVV 419
PAD R+YL I PE +DS FS++D ++ N EL+NNLGNF++RA FV+++F G V
Sbjct: 610 TGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMFVSKFFGGYV 669
Query: 420 PERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTA 479
PE L D+ L + + +L+ R +DAL+ +++++ GN+Y +PWK
Sbjct: 670 PEM-VLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQVNEPWKRI 728
Query: 480 K---EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLD----EVKRWEFR-E 531
K D+ R GT +++ I L ++L+P++P S I L L + F
Sbjct: 729 KGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSILLTNFLCT 788
Query: 532 LPAGHKVRKPEILFKKVTDDQIIYF----------------ILNYMAKGNPEGARILLDK 575
LPAGH++ LF+K+ +DQI ++ + P+ + L+D+
Sbjct: 789 LPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQQIQALMDE 848
Query: 576 YYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEK---KEGK 614
K+ +++R K + D+ EV V K + LK++ EGK
Sbjct: 849 VTKQGNIVRELKAQKADKNEVA-AEVAKLLDLKKQLAVAEGK 889
>gi|4826826 methionine-tRNA synthetase; Methioninyl-tRNA synthetase [Homo
sapiens] >gi|2829461|sp|P56192|SYM_HUMAN METHIONYL-TRNA
SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|2135628|pir||JC5224 methionine--tRNA ligase (EC
6.1.1.10) - human >gi|1702932|emb|CAA64381.1| (X94754)
yeast methionyl-tRNA synthetase homolog [Homo sapiens]
Length = 900
Score = 398 bits (1012), Expect = e-109
Identities = 224/642 (34%), Positives = 351/642 (53%), Gaps = 51/642 (7%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++TSALPY N H G++ G L AD+F RY RL+ + +++CGTDE+GT +AL+EG
Sbjct: 267 LITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEEG 326
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
+P+EI D++H ++ ISFD FGRT P K++Q+ F + + G +++ +Q
Sbjct: 327 LTPQEICDKYHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQDTVEQ 386
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
CEH FL DRFV G CP+CG E+ +GDQC+ CG+ + L P+C +C +
Sbjct: 387 LRCEHCARFLADRFVEGVCPFCGYEEARGDQCDKCGKLINAVELKKPQCKVCRSCPVVQS 446
Query: 185 SAHYYIKMQDFAERLKRWIEK----QPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
S H ++ + +RL+ W+ + W PN + + SW+ +GL+ R ITRDL WG PVP
Sbjct: 447 SQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQFITRSWLRDGLKPRCITRDLKWGTPVP 506
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
L E + KV YVWF+A IGY+SIT + ++W+++W N + Q + F+ KDN+
Sbjct: 507 L--EGFEDKVFYVWFDATIGYLSITANY------TDQWERWWKNPE-QVDLYQFMAKDNV 557
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFH++ +P + E + L + A EYL E KFS SR ++ D
Sbjct: 558 PFHSLVFPCSALG--------AEDNYTLVSHLIATEYLNYEDGKFSKSRGVGVFGDMAQD 609
Query: 361 V-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVV 419
PAD R+YL I PE +DS FS++D ++ N EL+NNLGNF++RA FV+++F G V
Sbjct: 610 TGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMFVSKFFGGYV 669
Query: 420 PERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTA 479
PE L D+ L + + +L+ R +DAL+ +++++ GN+Y +PWK
Sbjct: 670 PEM-VLTPDDQRLLGHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQVNEPWKRI 728
Query: 480 K---EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLD----EVKRWEFR-E 531
K D+ R GT +++ I L ++L+P++P S I L L + F
Sbjct: 729 KGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSILLTNFLCT 788
Query: 532 LPAGHKVRKPEILFKKVTDDQIIYF----------------ILNYMAKGNPEGARILLDK 575
LPAGH++ LF+K+ +DQI ++ + P+ + L+D+
Sbjct: 789 LPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQQIQALMDE 848
Query: 576 YYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEK---KEGK 614
K+ +++R K + D+ EV V K + LK++ EGK
Sbjct: 849 VTKQGNIVRELKAQKADKNEVA-AEVAKLLDLKKQLAVAEGK 889
>pir||H81552 methionyl-tRNA synthetase CP0651 [imported] - Chlamydophila
pneumoniae (strain AR39) >gi|7189567|gb|AAF38466.1|
(AE002223) methionyl-tRNA synthetase [Chlamydophila
pneumoniae AR39] >gi|8978496|dbj|BAA98333.1| (AP002545)
methionyl-tRNA synthetase [Chlamydophila pneumoniae
J138]
Length = 551
Score = 394 bits (1001), Expect = e-108
Identities = 205/521 (39%), Positives = 313/521 (59%), Gaps = 19/521 (3%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ ++TSALPYANGP+H GH+AG YLPAD++ R+ RL G+DV++ICG+DE G I+ A +
Sbjct: 4 KVLITSALPYANGPLHFGHIAGVYLPADVYARFRRLLGDDVLYICGSDEFGIAITLNADR 63
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
EG +E VD +H+ K TF++ + DFF RT P H +L Q+F+ + +G + +++
Sbjct: 64 EGLGYQEYVDMYHKLHKDTFEKLGFALDFFSRTTNPFHAELVQDFYSQLKASGLIENRIS 123
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
+Q Y E ++ FL DR+V GTCP CG + +GD+C+ CG LI+P+ I G +
Sbjct: 124 EQLYSEQEQRFLADRYVEGTCPRCGFDHARGDECQSCGADYEAIDLIDPKSKISGVELVK 183
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVPLD 242
+++ H Y + + L +I+ +V+ V+ +IE + RAITRDL+WGIPVP
Sbjct: 184 KETEHSYFLLDRMKDALLSFIQGCYLPDHVRKFVVDYIEH-VRSRAITRDLSWGIPVP-- 240
Query: 243 EEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPF 302
D GKV YVWF+APIGYIS T+E G P+EWK++WL DG + FIGKDN+PF
Sbjct: 241 --DFPGKVFYVWFDAPIGYISGTMEWAASQGNPDEWKRFWLE-DG-VEYVQFIGKDNLPF 296
Query: 303 HAIFWPAFLMAYGKYKD-EEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV 361
H++ +PA M G+ D ++V+A + +E+ LEG++FS S + + +FL
Sbjct: 297 HSVVFPA--MELGQKLDYKKVDA-------LVVSEFYLLEGRQFSKSEGNYVDMDKFLSS 347
Query: 362 FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNR-YFDGVVP 420
+ D LRY L PET DS+F+F DFK R N ELV GNF++R L F + ++D +
Sbjct: 348 YSLDKLRYVLAATAPETSDSEFTFLDFKTRCNSELVGKFGNFINRVLAFAEKNHYDKLSY 407
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
L++ DR LEE+ + ++ + Y + A +MSLA+ GN YF+ + PWK K
Sbjct: 408 HSVVLEDSDRAFLEEVRQLVRDAEKCYREYSLRKATSVIMSLAALGNVYFNQQAPWKLLK 467
Query: 481 E-DKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLN 520
E + R + + K L ++ P +P+++ IW +++
Sbjct: 468 EGTRERVEAILFCACYCQKLLALISYPIIPESAVAIWEMIS 508
>pir||H81718 methionyl-tRNA synthetase TC0301 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190341|gb|AAF39166.1| (AE002297)
methionyl-tRNA synthetase [Chlamydia muridarum]
Length = 550
Score = 393 bits (999), Expect = e-108
Identities = 204/523 (39%), Positives = 306/523 (58%), Gaps = 27/523 (5%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
R ++TSALPYANGP+H GH+ GAYLPAD++ R+ RL G++V++ICG+DE+G I+ A
Sbjct: 5 RILITSALPYANGPLHFGHITGAYLPADVYARFQRLLGKEVLYICGSDEYGIAITLNAEL 64
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +E VD +H+ K T ++ IS DFF RT P H + Q+F+ + G + VT
Sbjct: 65 AGMGYQEYVDMYHKLHKDTLKKLGISVDFFSRTTNPHHPAIVQDFYRNLQDKGLMENLVT 124
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q Y E ++ FL DR+V+GTCP CG + +GD+C+ CG L +PR + G+ +S
Sbjct: 125 DQLYSEEEEKFLADRYVVGTCPKCGFDRARGDECQQCGADYEARDLKDPRSKLTGKALSL 184
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVPLD 242
R++ H Y ++ E L ++E +P+++N V+ +I + L RA+TRDL+WG+PVP
Sbjct: 185 RETEHAYFHLERMKEELLTFVEGIYLRPHMRNFVIDYI-KNLRPRAVTRDLSWGVPVP-- 241
Query: 243 EEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPF 302
++ KV YVWF+APIGYIS T++ IG P+ WKK+WL D + F+GKDN F
Sbjct: 242 --GLENKVFYVWFDAPIGYISGTMDWAASIGDPDAWKKFWL--DDKVTYTQFVGKDNTSF 297
Query: 303 HAIFWPAFLMAYGKYKDEEVEAEWNLPYD----IPANEYLTLEGKKFSTSRNWAIWVHEF 358
H++ +PA +E +LPY + +E+L LEG +FS S I + F
Sbjct: 298 HSVIFPA------------MEMGQSLPYKKVDALVTSEFLLLEGFQFSKSEGNIIDMDAF 345
Query: 359 LDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV 418
L+ + D LRY L I PET DS+F+F +FK R N +LV GNFV+R + F + +G
Sbjct: 346 LETYSLDKLRYVLAAIAPETSDSEFAFQEFKTRCNSDLVGKFGNFVNRVVAFAAK--NGC 403
Query: 419 VP-ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
+L++ D E + E +K KE + Y + A +M LA+ GN YF+ + PWK
Sbjct: 404 TELSHPQLEQQDLEFIAEAQKLAKEAADHYQQYSLRKACSTIMELAALGNGYFNDQAPWK 463
Query: 478 TAKEDK-VRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLL 519
AKED R + + + K L ++ P +P+ + IW ++
Sbjct: 464 LAKEDLWNRVRSILFCACYCQKLLALISYPIMPETAWTIWGMI 506
>sp|Q9Z959|SYM_CHLPN METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7468456|pir||H72117 methionine--tRNA ligase (EC
6.1.1.10) - Chlamydophila pneumoniae (strain CWL029)
>gi|4376385|gb|AAD18275.1| (AE001598) Methionyl-tRNA
Synthetase [Chlamydophila pneumoniae CWL029]
Length = 551
Score = 392 bits (996), Expect = e-108
Identities = 205/521 (39%), Positives = 311/521 (59%), Gaps = 19/521 (3%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ ++TSALPYANGP+H GH+AG YLPAD++ R+ RL G+DV++ICG+DE G I+ A +
Sbjct: 4 KVLITSALPYANGPLHFGHIAGVYLPADVYARFRRLLGDDVLYICGSDEFGIAITLNADR 63
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
EG +E VD +H+ K TF++ + DFF RT P H +L Q+F+ + +G + +++
Sbjct: 64 EGLGYQEYVDMYHKLHKDTFEKLGFALDFFSRTTNPFHAELVQDFYSQLKASGLIENRIS 123
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
+Q Y E ++ FL DR+V GTCP CG + +GD+C+ CG LI P+ I G +
Sbjct: 124 EQLYSEQEQRFLADRYVEGTCPRCGFDHARGDECQSCGADYEAIDLIGPKSKISGVELVK 183
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVPLD 242
+++ H Y + + L +I+ +V+ V+ +IE + RAITRDL+WGIPVP
Sbjct: 184 KETEHSYFLLDRMKDALLSFIQGCYLPDHVRKFVVDYIEH-VRSRAITRDLSWGIPVP-- 240
Query: 243 EEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPF 302
D GKV YVWF+APIGYIS T+E G P+EWK++WL DG + FIGKDN+PF
Sbjct: 241 --DFPGKVFYVWFDAPIGYISGTMEWAASQGNPDEWKRFWLE-DG-VEYVQFIGKDNLPF 296
Query: 303 HAIFWPAFLMAYGKYKD-EEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV 361
H++ +PA M G+ D ++V+A + +E+ LEG++FS S + + +FL
Sbjct: 297 HSVVFPA--MELGQKLDYKKVDA-------LVVSEFYLLEGRQFSKSEGNYVDMDKFLSS 347
Query: 362 FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNR-YFDGVVP 420
+ D LRY L PET DS+F+F DFK R N ELV GNF++R L F + ++D +
Sbjct: 348 YSLDKLRYVLAATAPETSDSEFTFLDFKTRCNSELVGKFGNFINRVLAFAEKNHYDKLSY 407
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
L++ DR LEE + ++ + Y + A +MSLA+ GN YF+ + PWK K
Sbjct: 408 HSVVLEDSDRAFLEEARQLVRDAEKCYREYSLRKATSVIMSLAALGNVYFNQQAPWKLLK 467
Query: 481 E-DKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLN 520
E + R + + K L ++ P +P+++ IW +++
Sbjct: 468 EGTRERVEAILFCACYCQKLLALISYPIIPESAVAIWEMIS 508
>sp|O84035|SYM_CHLTR METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7468858|pir||C71567 methionine--tRNA ligase (EC
6.1.1.10) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328422|gb|AAC67622.1| (AE001277)
Methionyl-tRNA Synthetase [Chlamydia trachomatis]
Length = 550
Score = 391 bits (993), Expect = e-107
Identities = 210/523 (40%), Positives = 302/523 (57%), Gaps = 27/523 (5%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
R ++TSALPYANGP+H GH+ GAYLPAD++ R+ RL+G++V++ICG+DE+G I+ A
Sbjct: 5 RILITSALPYANGPLHFGHITGAYLPADVYARFQRLQGKEVLYICGSDEYGIAITLNAEL 64
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +E VD +H+ K TF++ IS DFF RT H + Q+F+ E G + +VT
Sbjct: 65 AGMGYQEYVDMYHKLHKDTFKKLGISVDFFSRTTNTYHPAIVQDFYRNLQERGLVENQVT 124
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
+Q Y E + FL DR+V+GTCP CG + +GD+C+ CG L PR + G +S
Sbjct: 125 EQLYSEEEGKFLADRYVVGTCPKCGFDRARGDECQQCGADYEARDLKEPRSKLTGAALSL 184
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVPLD 242
RD+ H Y+ ++ E L +++ +P+++N V +IE L RA+TRDL+WGIPVP
Sbjct: 185 RDTEHAYLHLERMKEDLLAFVQGIYLRPHMRNFVTDYIEH-LRPRAVTRDLSWGIPVP-- 241
Query: 243 EEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPF 302
D++ KV YVWF+APIGYIS T++ IG P WKK+WL D FIGKDN F
Sbjct: 242 --DLENKVFYVWFDAPIGYISGTMDWAASIGDPEAWKKFWL--DDTVTYAQFIGKDNTSF 297
Query: 303 HAIFWPAFLMAYGKYKDEEVEAEWNLPYD----IPANEYLTLEGKKFSTSRNWAIWVHEF 358
HA +PA +E +LPY + +E+L LEG +FS S I + F
Sbjct: 298 HAAIFPA------------MEIGQSLPYKKVDALVTSEFLLLEGFQFSKSDGNFIDMDAF 345
Query: 359 LDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV 418
L+ + D LRY L I PET DS+FSF +FK R N ELV GNFV+R L F + +G
Sbjct: 346 LETYSLDKLRYVLAAIAPETSDSEFSFQEFKTRCNSELVGKYGNFVNRVLAFAVK--NGC 403
Query: 419 VP-ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
+L++ D + + + +K K+ E Y + A +M LA+ GN YF+ + PWK
Sbjct: 404 TELSSPQLEQKDLDFISKSQKLAKDAAEHYAQYSLRKACSTIMELAALGNGYFNDEAPWK 463
Query: 478 TAKEDK-VRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLL 519
AKE R + + K L ++ P +P+ + KI ++
Sbjct: 464 LAKEGNWNRVRAILFCACYCQKLLALISYPIMPETALKILEMI 506
>sp|P00959|SYM_ECOLI METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|68542|pir||SYECMT methionine--tRNA ligase (EC
6.1.1.10) [validated] - Escherichia coli
>gi|42016|emb|CAA39315.1| (X55791) methionyl-tRNA
synthetase [Escherichia coli] >gi|146829|gb|AAA24161.1|
(K02671) methionyl-tRNA synthetase (metG) [Escherichia
coli] >gi|1788432|gb|AAC75175.1| (AE000300) methionine
tRNA synthetase [Escherichia coli K12]
Length = 677
Score = 382 bits (971), Expect = e-105
Identities = 237/727 (32%), Positives = 369/727 (50%), Gaps = 63/727 (8%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VT ALPYANG IH GH+ ++ AD++VRY R++G +V FIC D HGTPI +A +
Sbjct: 7 KILVTCALPYANGSIHLGHML-EHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQ 65
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P +++ E ++ + F IS+D + T + +LS+ + + ENG + +
Sbjct: 66 LGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTI 125
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q Y MFLPDRFV GTCP C + DQ GD CEVCG +P LI P+ + G
Sbjct: 126 SQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVM 185
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNW-GIPVPL 241
RDS H++ + F+E L+ W + V N + W E GL++ I+RD + G +P
Sbjct: 186 RDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIP- 244
Query: 242 DEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIP 301
+ GK YVW +APIGY+ + G + +YW D + HFIGKD +
Sbjct: 245 ---NAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKK-DSTAELYHFIGKDIVY 300
Query: 302 FHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV 361
FH++FWPA L + + P ++ + Y+T+ G K S SR I +L+
Sbjct: 301 FHSLFWPAMLEG----------SNFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNH 350
Query: 362 FPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
F AD LRYY T + D D + DF R+N ++VN + N R F+N+ FDGV+
Sbjct: 351 FDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLA 410
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
+ D + + A + +GE + F A++ +M+LA NRY D + PW AK
Sbjct: 411 S----ELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAK 466
Query: 481 ED--KVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP-AGHK 537
++ ++ + + + L L+P LP +E+ LN + W+ + P GHK
Sbjct: 467 QEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTE--LTWDGIQQPLLGHK 524
Query: 538 VRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVV 597
V + L+ ++ Q+ E ++ +KE+ A V
Sbjct: 525 VNPFKALYNRIDMRQV--------------------------EALVEASKEEVKAAAAPV 558
Query: 598 LRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVR 657
+ D ++E + FDDFAK+DLRV I + +DKL + +DLG E R
Sbjct: 559 TGPLADD-PIQET-------ITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKR 610
Query: 658 TLVAGLKKYY-KPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGER-VALLMPDKEV 715
+ +G++ Y P+ L+ R+ ++VANL P+K+R S+GM++AA G + + LL PD
Sbjct: 611 NVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGA 670
Query: 716 KLGAKVR 722
K G +V+
Sbjct: 671 KPGHQVK 677
>gb|AAA60526.1| (U00007) methionyl-tRNA synthetase [Escherichia coli]
>gi|744213|prf||2014253G Met-tRNA synthetase
[Escherichia coli]
Length = 680
Score = 382 bits (971), Expect = e-105
Identities = 237/727 (32%), Positives = 369/727 (50%), Gaps = 63/727 (8%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VT ALPYANG IH GH+ ++ AD++VRY R++G +V FIC D HGTPI +A +
Sbjct: 10 KILVTCALPYANGSIHLGHML-EHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQ 68
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P +++ E ++ + F IS+D + T + +LS+ + + ENG + +
Sbjct: 69 LGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTI 128
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q Y MFLPDRFV GTCP C + DQ GD CEVCG +P LI P+ + G
Sbjct: 129 SQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVM 188
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNW-GIPVPL 241
RDS H++ + F+E L+ W + V N + W E GL++ I+RD + G +P
Sbjct: 189 RDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIP- 247
Query: 242 DEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIP 301
+ GK YVW +APIGY+ + G + +YW D + HFIGKD +
Sbjct: 248 ---NAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKK-DSTAELYHFIGKDIVY 303
Query: 302 FHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV 361
FH++FWPA L + + P ++ + Y+T+ G K S SR I +L+
Sbjct: 304 FHSLFWPAMLEG----------SNFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNH 353
Query: 362 FPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
F AD LRYY T + D D + DF R+N ++VN + N R F+N+ FDGV+
Sbjct: 354 FDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLA 413
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
+ D + + A + +GE + F A++ +M+LA NRY D + PW AK
Sbjct: 414 S----ELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAK 469
Query: 481 ED--KVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP-AGHK 537
++ ++ + + + L L+P LP +E+ LN + W+ + P GHK
Sbjct: 470 QEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTE--LTWDGIQQPLLGHK 527
Query: 538 VRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVV 597
V + L+ ++ Q+ E ++ +KE+ A V
Sbjct: 528 VNPFKALYNRIDMRQV--------------------------EALVEASKEEVKAAAAPV 561
Query: 598 LRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVR 657
+ D ++E + FDDFAK+DLRV I + +DKL + +DLG E R
Sbjct: 562 TGPLADD-PIQET-------ITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKR 613
Query: 658 TLVAGLKKYY-KPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGER-VALLMPDKEV 715
+ +G++ Y P+ L+ R+ ++VANL P+K+R S+GM++AA G + + LL PD
Sbjct: 614 NVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGA 673
Query: 716 KLGAKVR 722
K G +V+
Sbjct: 674 KPGHQVK 680
>pir||D82249 methionyl-tRNA synthetase VC1036 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655500|gb|AAF94195.1|
(AE004185) methionyl-tRNA synthetase [Vibrio cholerae]
Length = 731
Score = 378 bits (960), Expect = e-103
Identities = 238/730 (32%), Positives = 365/730 (49%), Gaps = 65/730 (8%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VT ALPYANG IH GH+ ++ ADI+VRY RL+G V FIC D HGTPI +A +
Sbjct: 55 KLLVTCALPYANGSIHLGHML-EHIQADIWVRYQRLRGNTVNFICADDAHGTPIMLKAQQ 113
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P +++ E+ + F ISFD + T + +L+ +L+ +NG + +
Sbjct: 114 MGMTPEAMIEMVSEEHQRDFAGFDISFDNYHSTHSDENRELASHIYLQLKKNGFISSRTI 173
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q + +MFLPDRFV GTCP C +EDQ GD C+ CG +P LINP+ A+ G
Sbjct: 174 SQLFDPEKEMFLPDRFVKGTCPKCKSEDQYGDNCDACGETYSPTELINPKSAVSGATPVM 233
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNW-GIPVPL 241
+DS H++ + F LK W + N + W E GL++ I+RD + G +P
Sbjct: 234 KDSEHFFFDLPQFESMLKEWTRSGSLQSETANKMQEWFEGGLQQWDISRDAPYFGFEIPG 293
Query: 242 DEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPN---EWKKYWLNIDGQTRVIHFIGKD 298
+ K K YVW +APIGY+ FK + ++ +YW N D +T + HFIGKD
Sbjct: 294 E----KDKFFYVWLDAPIGYMG----SFKNLCDKRGDLDFNEYW-NKDSKTELYHFIGKD 344
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
+ FH++FWPA L G K P ++ + Y+T+ G K S S+ + +
Sbjct: 345 IVYFHSLFWPAMLDGSGFRK----------PTNVFVHGYVTVNGAKMSKSKGTFVKASTY 394
Query: 359 LDVFPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
L+ + LRYY + D D + DF R+N ++VN + N R F+ + FDG
Sbjct: 395 LNHLDPECLRYYYAAKLNNRIDDLDLNLEDFTQRVNADVVNKIVNLASRNAGFITKRFDG 454
Query: 418 VVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
+ EL E A + EL F A++ + +LA N+Y D K PW
Sbjct: 455 KLSAHFAEPEL----YAEFAGAADRIAELFEAREFGRAIREITALADKANQYVDEKAPWV 510
Query: 478 TAKED----KVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP 533
AK++ ++ TV I+L + L L+P +P +E+ LN + WE P
Sbjct: 511 VAKQEGQDQALQDICTVGINL--FRVLMTYLKPVMPALAERTEAFLN--QELTWEGVATP 566
Query: 534 -AGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGD 592
H V + LF ++ Q+ E +I +K +
Sbjct: 567 LTDHAVTPFKALFNRIDPKQV--------------------------EAMIEASKAEAAA 600
Query: 593 EAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDL 652
E K + + K+ ++FDDFAK+DLR+ KI+ + +DKL ++D+
Sbjct: 601 EKAAADAAKPKSAETELSKDPLAAEIEFDDFAKVDLRIAKILSCEAVEKSDKLLKFELDI 660
Query: 653 GDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAA-DDGERVALLMP 711
G E R + +G+K Y+PE+L+ +Y VVVANL+P+K++ S+GM+LAA G + LL P
Sbjct: 661 GGETRQVFSGIKSAYQPEDLIGKYTVVVANLKPRKMKFGMSEGMILAAGPGGSDLWLLEP 720
Query: 712 DKEVKLGAKV 721
+ + G +V
Sbjct: 721 HQGAQAGMRV 730
>emb|CAA24627.1| (V01316) tRNA synthetase [Saccharomyces cerevisiae]
>gi|171934|gb|AAA88726.1| (J01339) methionyl-tRNA
synthetase [Saccharomyces cerevisiae]
Length = 751
Score = 374 bits (950), Expect = e-102
Identities = 205/566 (36%), Positives = 316/566 (55%), Gaps = 42/566 (7%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++TSALPY N H G++ G+ L ADIF RY + + + +FICGTDE+GT +AL+EG
Sbjct: 199 LITSALPYVNNVPHLGNIIGSVLSADIFARYCKGRNYNALFICGTDEYGTATETKALEEG 258
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
+PR++ D++H+ ++ +I FD+FGRT +++Q F K NG+L ++ KQ
Sbjct: 259 VTPRQLCDKYHKIHSDVYKWFQIGFDYFGRTTTDKQTEIAQHIFTKLNSNGYLEEQSMKQ 318
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
YC +L DR+V G CP C +D +GDQC+ CG L P LINPRC + +
Sbjct: 319 LYCPVHNSYLADRYVEGECPKCHYDDARGDQCDKCGALLDPFELINPRCKLDDASPEPKY 378
Query: 185 SAHYYIKMQDFAERLKRWIEKQP----WKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
S H ++ + ++ W+EK W N K + SW+++GL+ R ITRDL WG PVP
Sbjct: 379 SDHIFLSLDKLESQISEWVEKASEEGNWSKNSKTITQSWLKDGLKPRCITRDLVWGTPVP 438
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
L E K KVLYVWF+A IGY+SIT + K EWK++W N + + F+GKDN+
Sbjct: 439 L--EKYKDKVLYVWFDATIGYVSITSNYTK------EWKQWWNNPE-HVSLYQFMGKDNV 489
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFH + +P + E W + + + EYL E KFS SR ++ + D
Sbjct: 490 PFHTVVFPGSQLG--------TEENWTMLHHLNTTEYLQYENGKFSKSRGVGVFGNNAQD 541
Query: 361 --VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV 418
+ P+ + RYYL ++ PE+ DS FS+ DF R N EL+ NLGNFV+R + FVN ++GV
Sbjct: 542 SGISPSVW-RYYLASVRPESSDSHFSWDDFVARNNSELLANLGNFVNRLIKFVNAKYNGV 600
Query: 419 VPERGELDELDREALEEIEKAFKEVGELIMNY-------RFKDALKRVMSLASFGNRYFD 471
VP + D + + + K++ E++ NY + L+ MSL++ GN++
Sbjct: 601 VP------KFDPKKVSNYDGLVKDINEILSNYVKEMELGHERRGLEIAMSLSARGNQFLQ 654
Query: 472 HKQPWKTA-KEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVK---RW 527
+ T + ++ V + L I+ A+ ++ P++P+ EKI +LN +K R+
Sbjct: 655 ENKLDNTLFSQSPEKSDAVVAVGLNIIYAVSSIITPYMPEIGEKINKMLNAPALKIDDRF 714
Query: 528 EFRELPAGHKVRKPEILFKKVTDDQI 553
L GH + K E LF+++ + +I
Sbjct: 715 HLAIL-EGHNINKAEYLFQRIDEKKI 739
>gi|6321704 methionyl tRNA synthetase; Mes1p [Saccharomyces cerevisiae]
>gi|1711639|sp|P00958|SYMC_YEAST METHIONYL-TRNA
SYNTHETASE, CYTOPLASMIC (METHIONINE--TRNA LIGASE)
(METRS) >gi|2144553|pir||SYBYMT methionine--tRNA ligase
(EC 6.1.1.10), cytosolic - yeast (Saccharomyces
cerevisiae) >gi|1323481|emb|CAA97293.1| (Z73049) ORF
YGR264c [Saccharomyces cerevisiae]
>gi|1536956|emb|CAA69086.1| (Y07777) methionine--tRNA
ligase [Saccharomyces cerevisiae]
Length = 751
Score = 374 bits (950), Expect = e-102
Identities = 205/566 (36%), Positives = 316/566 (55%), Gaps = 42/566 (7%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++TSALPY N H G++ G+ L ADIF RY + + + +FICGTDE+GT +AL+EG
Sbjct: 199 LITSALPYVNNVPHLGNIIGSVLSADIFARYCKGRNYNALFICGTDEYGTATETKALEEG 258
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
+PR++ D++H+ ++ +I FD+FGRT +++Q F K NG+L ++ KQ
Sbjct: 259 VTPRQLCDKYHKIHSDVYKWFQIGFDYFGRTTTDKQTEIAQHIFTKLNSNGYLEEQSMKQ 318
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
YC +L DR+V G CP C +D +GDQC+ CG L P LINPRC + +
Sbjct: 319 LYCPVHNSYLADRYVEGECPKCHYDDARGDQCDKCGALLDPFELINPRCKLDDASPEPKY 378
Query: 185 SAHYYIKMQDFAERLKRWIEKQP----WKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
S H ++ + ++ W+EK W N K + SW+++GL+ R ITRDL WG PVP
Sbjct: 379 SDHIFLSLDKLESQISEWVEKASEEGNWSKNSKTITQSWLKDGLKPRCITRDLVWGTPVP 438
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
L E K KVLYVWF+A IGY+SIT + K EWK++W N + + F+GKDN+
Sbjct: 439 L--EKYKDKVLYVWFDATIGYVSITSNYTK------EWKQWWNNPE-HVSLYQFMGKDNV 489
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFH + +P + E W + + + EYL E KFS SR ++ + D
Sbjct: 490 PFHTVVFPGSQLG--------TEENWTMLHHLNTTEYLQYENGKFSKSRGVGVFGNNAQD 541
Query: 361 --VFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV 418
+ P+ + RYYL ++ PE+ DS FS+ DF R N EL+ NLGNFV+R + FVN ++GV
Sbjct: 542 SGISPSVW-RYYLASVRPESSDSHFSWDDFVARNNSELLANLGNFVNRLIKFVNAKYNGV 600
Query: 419 VPERGELDELDREALEEIEKAFKEVGELIMNY-------RFKDALKRVMSLASFGNRYFD 471
VP + D + + + K++ E++ NY + L+ MSL++ GN++
Sbjct: 601 VP------KFDPKKVSNYDGLVKDINEILSNYVKEMELGHERRGLEIAMSLSARGNQFLQ 654
Query: 472 HKQPWKTA-KEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVK---RW 527
+ T + ++ V + L I+ A+ ++ P++P+ EKI +LN +K R+
Sbjct: 655 ENKLDNTLFSQSPEKSDAVVAVGLNIIYAVSSIITPYMPEIGEKINKMLNAPALKIDDRF 714
Query: 528 EFRELPAGHKVRKPEILFKKVTDDQI 553
L GH + K E LF+++ + +I
Sbjct: 715 HLAIL-EGHNINKAEYLFQRIDEKKI 739
>sp|Q20970|SYM_CAEEL PROBABLE METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE)
(METRS) >gi|7504593|pir||T22898 hypothetical protein
F58B3.5 - Caenorhabditis elegans
>gi|3877884|emb|CAA97803.1| (Z73427) Similarity to Yeast
methionyl-tRNA synthetase (SW:SYMC_YEAST), contains
similarity to Pfam domain: PF00133 (tRNA synthetases
class I (I, L, M and V)), Score=92.3, E-value=3.2e-24,
N=1; PF01588 (Putative tRNA binding domain),
Score=170.4, E-val>
Length = 917
Score = 371 bits (942), Expect = e-101
Identities = 210/602 (34%), Positives = 319/602 (52%), Gaps = 30/602 (4%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++T+ALPY N H G++ G L AD+F RY L+G ++ GTDE+GT +AL+EG
Sbjct: 38 LITAALPYVNNVPHLGNIIGCVLSADVFARYCNLRGHQTFYVGGTDEYGTATETKALQEG 97
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
+PRE+ D++H K ++ I F FGRT ++ Q+ FLK ++NG+ + Q
Sbjct: 98 CTPRELCDKYHAIHKGIYEWFGIDFSHFGRTTTDHQTEICQDMFLKLHKNGYTSSQSVDQ 157
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
YC + FL DRFV GTCP C +D +GDQC+ CG+ + L + +C +C +
Sbjct: 158 LYCNQCEKFLADRFVTGTCPMCAYDDARGDQCDGCGKLINAVDLKDAKCHMCKATPEVKQ 217
Query: 185 SAHYYIKM----QDFAERLKRWIEKQP--WKPNVKNMVLSWIEEGLEERAITRDLNWGIP 238
S H ++ + Q E L R + K+ W N + +W++ GL+ R ITRDL WG
Sbjct: 218 STHIFLSLDKLQQKTTEHLDRELAKEDNRWSSNAVGITKAWMKLGLDPRCITRDLKWGTA 277
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKD 298
VPLD + KV YVWF+APIGY+SIT + + W K+W N + + +F+GKD
Sbjct: 278 VPLD--GFEKKVFYVWFDAPIGYLSIT-----KCVLGDNWTKWWKNPE-NVELFNFVGKD 329
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
N+ FHA+ +P + + + ++ A EYL E KFS SR I+
Sbjct: 330 NVAFHAVMFPCSQLG--------ANDNYTVVNNLCATEYLNYEDTKFSKSRGTGIFGDAA 381
Query: 359 LDV-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
PAD R+YL + PE++D+ FS+ DF +++N EL+NNLGNF++RAL+FV F G
Sbjct: 382 QGTEIPADIWRFYLLYMRPESQDTAFSWDDFVLKVNSELLNNLGNFINRALSFVANSFGG 441
Query: 418 VVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
VVPE L D E L EI + + KDA+K +++++ GN+Y + PW
Sbjct: 442 VVPEM-NLTNDDAEVLSEIHNECMQWDKQFDGVHLKDAVKTILNVSRLGNQYMQAQTPWV 500
Query: 478 TAKED---KVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEV---KRWEFRE 531
K+D K R GT + ++ I + +LL P +P S I L + +
Sbjct: 501 LMKKDEEGKKRAGTIIGVAANIAYHVSVLLYPIMPTISATIREQCGLPALPLFTPFPICY 560
Query: 532 LPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFG 591
L AGHK+ +P LF+K+ QI F + + + + + K++ K+K G
Sbjct: 561 LKAGHKIGQPSPLFQKLDPAQIAEFKAKFGGSQDAQSSAPKTAEKPKQQKKQAPTKDKKG 620
Query: 592 DE 593
D+
Sbjct: 621 DK 622
Score = 86.6 bits (211), Expect = 9e-16
Identities = 46/122 (37%), Positives = 77/122 (62%), Gaps = 6/122 (4%)
Query: 606 KLKEKKEGKEMYVKFD-----DFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEV-RTL 659
K KE+K+GK D +LD+RVG+II+ + HP+AD LYV ++D+G+ RT+
Sbjct: 735 KAKEQKKGKGGAAAAPVDDTIDVGRLDMRVGRIIKCEKHPDADALYVEQIDVGESAPRTV 794
Query: 660 VAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGA 719
V+GL ++ +++ NR VVV+ NL+P K+RG+ S+ M++ A ++V ++ + K G
Sbjct: 795 VSGLVRHVPLDQMQNRLVVVLCNLKPAKMRGVESRAMVMCASSPDKVEIMEVPADSKPGT 854
Query: 720 KV 721
V
Sbjct: 855 PV 856
>sp|P43828|SYM_HAEIN METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|1075016|pir||I64113 methionine--tRNA ligase (EC
6.1.1.10) - Haemophilus influenzae (strain Rd KW20)
>gi|1574731|gb|AAC22924.1| (U32807) methionyl-tRNA
synthetase (metG) [Haemophilus influenzae Rd]
Length = 682
Score = 368 bits (934), Expect = e-100
Identities = 234/727 (32%), Positives = 360/727 (49%), Gaps = 58/727 (7%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VT ALPYANG IH GH+ ++ ADI+VR+ R++G + F+C D HGTPI A K
Sbjct: 7 KILVTCALPYANGAIHLGHML-EHIQADIWVRFQRMRGNKIHFVCADDAHGTPIMLNADK 65
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P E++ + F ISFD + T + +L+ E + K NG + KV
Sbjct: 66 LGITPEELIAKAKADHIRDFAGFNISFDNYHSTHSEENKQLTAEIYNKLKANGFIKSKVI 125
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q + MFLPDRFV GTCP C AEDQ GD CEVC +P LINPR A+ G
Sbjct: 126 SQLFDPEKNMFLPDRFVKGTCPKCKAEDQYGDNCEVCASTYSPMDLINPRSAVSGTTPIV 185
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNW-GIPVPL 241
++S H++ + F LK W + + N + W E L++ I+RD + G +P
Sbjct: 186 KESEHFFFDLPAFEGMLKEWTRSGSLQSEIANKMQEWFESDLQQWDISRDAPYFGFEIP- 244
Query: 242 DEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIP 301
K K YVW +APIGY++ R G ++ ++W + HFIGKD +
Sbjct: 245 ---GAKDKFFYVWLDAPIGYMASFKNLCNREG--IDFNEFWAE-GSDAELYHFIGKDIVY 298
Query: 302 FHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV 361
FH++FWPA L G K P ++ A+ Y+T++G K S SR I +L+
Sbjct: 299 FHSLFWPAMLEGSGYRK----------PTNVFAHGYVTVDGAKMSKSRGTFIQASTYLNH 348
Query: 362 FPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
+ LRYY + D DF+ DF R+N ++VN L N R F+ + F+G +
Sbjct: 349 IDPECLRYYYAAKLNDRIEDLDFNLEDFVQRVNTDIVNKLVNLASRNAGFIAKRFEGKLA 408
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
++ E D+ E +++ + + ++ +M+L N+Y D K PW AK
Sbjct: 409 DKLE----DKSLFAEFTAQAEQIAAYYESREYNKTIREIMALTDKANKYIDEKAPWVIAK 464
Query: 481 ED--KVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP-AGHK 537
E+ + ++ +++ + L L+P LP +E+ L + RW+ P GH
Sbjct: 465 EEGKEAELQAVCSMGIELFRVLMSYLKPVLPKLAERAETFLQAE--LRWDNIHQPLLGHT 522
Query: 538 VRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVV 597
+ + LF ++ QI D + + A K ++ E
Sbjct: 523 LAPFKALFSRLEKKQI--------------------DAVVEETKALFAAANKAAEKTEA- 561
Query: 598 LRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVR 657
K L + E + DDFAKLD+RV K+++ + P ++KL ++DLGD R
Sbjct: 562 -----KPTALSAVEPIAET-ITIDDFAKLDMRVAKVLKCEAVPESNKLLRFELDLGDHTR 615
Query: 658 TLVAGLK-KYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAA-DDGERVALLMPDKEV 715
+ +G+K Y KPEEL R+V++VANL P+K++ S+GM+L+A G + LL D V
Sbjct: 616 QVFSGIKAAYNKPEELEGRFVIMVANLAPRKMKFGVSEGMILSAGTGGSDLFLLSADSGV 675
Query: 716 KLGAKVR 722
G +V+
Sbjct: 676 TAGMQVK 682
>pir||T39696 methionyl trna synthetase - fission yeast (Schizosaccharomyces
pombe) >gi|5679723|emb|CAB51763.1| (AL109652) methionyl
trna synthetase [Schizosaccharomyces pombe]
Length = 782
Score = 364 bits (924), Expect = 2e-99
Identities = 194/560 (34%), Positives = 308/560 (54%), Gaps = 32/560 (5%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++TSALPY N H G++ G+ L AD+F RY R + + ++ICGTDE+GT +AL+EG
Sbjct: 225 LITSALPYVNNVPHLGNIVGSTLSADVFARYHRARNHNTLYICGTDEYGTATETKALEEG 284
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
SP+E+ D++H K + +I FD FGRT P ++Q F K Y N ++ Q
Sbjct: 285 VSPKELCDKYHALHKEVYDWFEIDFDHFGRTTTPKQTGIAQHIFTKLYNNDYMAIDTMTQ 344
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
YCE + +L DR+V GTCP CG +D +GDQC+ CG L LI+P+C + R+
Sbjct: 345 LYCEVHQGYLADRYVEGTCPKCGYDDARGDQCDGCGGLLNAFELIDPKCKLDRATPVKRE 404
Query: 185 SAHYYIKMQDFAERLKRWIEKQ----PWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
+ H ++ + ++ W + W N +++ SW++EGL R ITRDL WG PVP
Sbjct: 405 TKHVFLSLDKLQPAVESWAMQSAVEGKWSNNGRSITESWLKEGLRPRCITRDLKWGTPVP 464
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
L E+ KGKVLYVWF+A IGYISIT + +EW+K+W N + Q ++ F+GKDN+
Sbjct: 465 L--EEFKGKVLYVWFDATIGYISITANY------TDEWEKWWRNPE-QVKLYQFMGKDNV 515
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFH + +P+ L+ G+ +W + + I +YL E KFS SR ++ + D
Sbjct: 516 PFHTVIFPSSLLGTGE--------KWTMLHHINTTDYLNYETGKFSKSRGVGVFGNTAQD 567
Query: 361 V-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVV 419
+ RYYL + PET D+ F++ +F R N EL+ NLGNFV+R L F ++G+V
Sbjct: 568 IGLSPSVWRYYLLSSRPETSDTMFTWKEFITRHNSELLANLGNFVNRTLKFTTAKYNGLV 627
Query: 420 PE-----RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYF-DHK 473
P +L + ++++ + + + ++ L+ M +++ GN+Y D++
Sbjct: 628 PHYLTDPSVGAGKLKADFVKDVNALLAKYNAALEASKLREGLRLAMEISARGNQYLQDNR 687
Query: 474 QPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEV---KRWEFR 530
K ++ + + +L ++ L + P++P S I+ LN WE
Sbjct: 688 IDNKCYLYERQKCADAIGYALNLIYLLAAIFYPYMPSTSTSIYKQLNAPAAAIPDTWELC 747
Query: 531 ELPAGHKVRKPEILFKKVTD 550
LP GH++ +PE LF ++ +
Sbjct: 748 LLP-GHRIGEPEYLFTRIDE 766
>dbj|BAA21422.1| (AB004537) methionyl-tRNA synthetase [Schizosaccharomyces pombe]
Length = 577
Score = 364 bits (924), Expect = 2e-99
Identities = 194/560 (34%), Positives = 308/560 (54%), Gaps = 32/560 (5%)
Query: 5 MVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG 64
++TSALPY N H G++ G+ L AD+F RY R + + ++ICGTDE+GT +AL+EG
Sbjct: 20 LITSALPYVNNVPHLGNIVGSTLSADVFARYHRARNHNTLYICGTDEYGTATETKALEEG 79
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
SP+E+ D++H K + +I FD FGRT P ++Q F K Y N ++ Q
Sbjct: 80 VSPKELCDKYHALHKEVYDWFEIDFDHFGRTTTPKQTGIAQHIFTKLYNNDYMAIDTMTQ 139
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
YCE + +L DR+V GTCP CG +D +GDQC+ CG L LI+P+C + R+
Sbjct: 140 LYCEVHQGYLADRYVEGTCPKCGYDDARGDQCDGCGGLLNAFELIDPKCKLDRATPVKRE 199
Query: 185 SAHYYIKMQDFAERLKRWIEKQ----PWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVP 240
+ H ++ + ++ W + W N +++ SW++EGL R ITRDL WG PVP
Sbjct: 200 TKHVFLSLDKLQPAVESWAMQSAVEGKWSNNGRSITESWLKEGLRPRCITRDLKWGTPVP 259
Query: 241 LDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNI 300
L E+ KGKVLYVWF+A IGYISIT + +EW+K+W N + Q ++ F+GKDN+
Sbjct: 260 L--EEFKGKVLYVWFDATIGYISITANY------TDEWEKWWRNPE-QVKLYQFMGKDNV 310
Query: 301 PFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLD 360
PFH + +P+ L+ G+ +W + + I +YL E KFS SR ++ + D
Sbjct: 311 PFHTVIFPSSLLGTGE--------KWTMLHHINTTDYLNYETGKFSKSRGVGVFGNTAQD 362
Query: 361 V-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVV 419
+ RYYL + PET D+ F++ +F R N EL+ NLGNFV+R L F ++G+V
Sbjct: 363 IGLSPSVWRYYLLSSRPETSDTMFTWKEFITRHNSELLANLGNFVNRTLKFTTAKYNGLV 422
Query: 420 PE-----RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYF-DHK 473
P +L + ++++ + + + ++ L+ M +++ GN+Y D++
Sbjct: 423 PHYLTDPSVGAGKLKADFVKDVNALLAKYNAALEASKLREGLRLAMEISARGNQYLQDNR 482
Query: 474 QPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEV---KRWEFR 530
K ++ + + +L ++ L + P++P S I+ LN WE
Sbjct: 483 IDNKCYLYERQKCADAIGYALNLIYLLAAIFYPYMPSTSTSIYKQLNAPAAAIPDTWELC 542
Query: 531 ELPAGHKVRKPEILFKKVTD 550
LP GH++ +PE LF ++ +
Sbjct: 543 LLP-GHRIGEPEYLFTRIDE 561
>pir||C83210 methionyl-tRNA synthetase PA3482 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949627|gb|AAG06870.1|AE004769_3 (AE004769)
methionyl-tRNA synthetase [Pseudomonas aeruginosa]
Length = 677
Score = 345 bits (875), Expect = 1e-93
Identities = 228/731 (31%), Positives = 355/731 (48%), Gaps = 70/731 (9%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VTSALPYANG IH GH+ Y+ D++VR+ +++G V++C D HG+ I RA +
Sbjct: 6 KILVTSALPYANGSIHLGHML-EYIQTDMWVRFQKMRGNQAVYVCADDAHGSAIMLRAER 64
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
EG + +++D + F + FD + T + +LS +LK + GH+ +
Sbjct: 65 EGITSEQLIDAVRAEHMGDFADFLVDFDNYHSTHSEENRELSSAIYLKLRDAGHIDTRPV 124
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q + +MFL DRF+ GTCP CG DQ GD CE CG P L +P+ AI G
Sbjct: 125 TQYFDPEKQMFLADRFIKGTCPKCGTADQYGDNCEACGATYAPTELKDPKSAISGATPVL 184
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNW-GIPVPL 241
++S HY+ K+ DF LK+W + +V N + W++ GL++ I+RD + G +P
Sbjct: 185 KESLHYFFKLPDFEAMLKQWTRSGALQESVANKLAEWLDSGLQQWDISRDAPYFGFEIP- 243
Query: 242 DEEDMKGKVLYVWFEAPIGYISITIEHFKRI--GKPN-EWKKYWLNIDGQTRVIHFIGKD 298
D GK YVW +APIGY++ FK + +P ++ +W D + HFIGKD
Sbjct: 244 ---DAPGKYFYVWLDAPIGYMA----SFKNLCARRPELDFDAFW-GKDSGAELYHFIGKD 295
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
+ FHA+FWPA L G K P + + YLT+ G+K S SR + +
Sbjct: 296 IVNFHALFWPAMLEGAGYRK----------PTALNVHGYLTVNGQKMSKSRGTFVKARTY 345
Query: 359 LDVFPADYLRYYLTTIMPE-TRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
LD +YLRYY + + D D + DF ++N +LV + N R F+++ G
Sbjct: 346 LDHLDPEYLRYYYASKLGRGVEDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNAG 405
Query: 418 VVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
V+ EL L +A + E F A++ +M+LA N + + PW
Sbjct: 406 VLVGADPAPEL----LAAFREAAPGIAEAYEARDFNRAMREIMALADRANAWIAEQAPWA 461
Query: 478 TAK----EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP 533
AK +DKV+ + + + + L I L+P LP + LN+ + + + L
Sbjct: 462 LAKQEGQQDKVQ--AVCGLGINLFRQLVIFLKPVLPKLAAAAEAFLNVAPLTWADHQTLL 519
Query: 534 AGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDE 593
A H++ + L ++ E A++ +ED+ A +
Sbjct: 520 ANHQLNPFQPLMTRI------------------EPAKVEAMIEASKEDL--AAASQPAGN 559
Query: 594 AEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLG 653
E+V KE + FD FA +DLR+ I + + ADKL + +D+G
Sbjct: 560 GELV-------------KEPIAAEIDFDAFAAVDLRIALIEKCEFVEGADKLLRLSLDIG 606
Query: 654 DEVRTLVAGLKKYY-KPEELLNRYVVVVANLEPKKLRGIGSQGMLLAA-DDGERVALLMP 711
D R + +G+K Y P L R + VANL P+K++ S+GM+LAA GE + LL P
Sbjct: 607 DAKRNVFSGIKSAYPDPSALEGRLTLYVANLAPRKMKFGVSEGMVLAAGPGGEEIYLLSP 666
Query: 712 DKEVKLGAKVR 722
D K G +V+
Sbjct: 667 DSGAKPGQRVK 677
>pir||C82792 methionyl-tRNA synthetase XF0549 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105408|gb|AAF83359.1|AE003902_4
(AE003902) methionyl-tRNA synthetase [Xylella
fastidiosa]
Length = 702
Score = 344 bits (873), Expect = 2e-93
Identities = 244/738 (33%), Positives = 347/738 (46%), Gaps = 64/738 (8%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M +VT+ALPYANGP+H GHL G Y+ ADI+VR RL G + F+C D HGTPI A
Sbjct: 13 MTTALVTTALPYANGPLHLGHLVG-YIQADIWVRARRLGGHNTWFVCADDTHGTPIMLAA 71
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
K G P + + F ++FD + T P++ L+++ +L + GH+ +
Sbjct: 72 EKAGMPPEAFIATTQASHERDFAAFNVAFDHYDSTHSPVNRHLTEQSYLTLKQAGHITCR 131
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
Q Y MFLPDR+V GTCP CGA DQ GD CE CG P L NP I G
Sbjct: 132 SVAQFYDPAKGMFLPDRYVKGTCPNCGATDQYGDNCEACGATYDPTELKNPYSVISGTTP 191
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEE--GLEERAITRDLNW-GI 237
RDS H++ ++ F L+ W+ P+VKN + W++ GL I+RD + G
Sbjct: 192 ELRDSEHFFFEVAHFDTFLRHWLSGDVALPSVKNKLKEWLDAKGGLRPWDISRDAPYFGF 251
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
+P + GK YVW +APIGY+ RIG+ + L T + HFIGK
Sbjct: 252 EIP----NQPGKYFYVWLDAPIGYLCSFKTLCTRIGEDFDTH---LRSGTTTELHHFIGK 304
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHE 357
D + FHA+FWPA L G P + N YLT++G K S SR I
Sbjct: 305 DIVNFHALFWPAVLHGTGH----------RAPTRLHVNGYLTVDGAKMSKSRGTFIMART 354
Query: 358 FLDV-FPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYF 415
+LD D LRYY + D D + SDF R+N +LV L N R +F+ F
Sbjct: 355 YLDAGLEPDALRYYFAAKSSGDVDDLDLNLSDFVARVNADLVGKLVNLASRCASFIGTRF 414
Query: 416 DG----VVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFD 471
+G +P+R + D+ AL I A++ A+++ M LA N+Y D
Sbjct: 415 NGQLADTLPDRIQYDQF-VAALTPIRDAYERNDT-------ASAIRQTMQLADEANKYID 466
Query: 472 HKQPWKTAKEDK--VRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEF 529
+PW AK+ + L + + L L+P LP S + L V W+
Sbjct: 467 ETKPWIIAKQHNADAQLHAVCTQGLNLFRVLITALKPILPHTSIQAETFL-AAPVTAWQD 525
Query: 530 RELP--AGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAK 587
P GH + LF ++ D ++I ++N +D + A
Sbjct: 526 VNQPLIGGHTIHPYSPLFTRI-DKKVIEVMIN------------------ASKDTL--AP 564
Query: 588 EKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYV 647
+ + EK E + DDFAKLDLR+GK++ + +DKL
Sbjct: 565 PPASAKQQNASMSNTAPPPTAEKPETTAPTIGIDDFAKLDLRIGKVLVCEYVEGSDKLLR 624
Query: 648 VKVDLGD-EVRTLVAGLK-KYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAAD-DGE 704
++D G R + +G++ Y PE L+ R VV +ANL P+K+R SQGM+L+A D
Sbjct: 625 FELDAGPLGKRQIFSGIRASYSNPETLIGRNVVFIANLAPRKMRFGISQGMILSAGFDSG 684
Query: 705 RVALLMPDKEVKLGAKVR 722
+ALL D + G VR
Sbjct: 685 TLALLDADSSAQPGMPVR 702
>pir||G82022 methionine--tRNA ligase (EC 6.1.1.10) NMA0275 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379037|emb|CAB83583.1| (AL162752) methionyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 685
Score = 339 bits (861), Expect = 5e-92
Identities = 227/739 (30%), Positives = 361/739 (48%), Gaps = 78/739 (10%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VTSALPYANG IH GH+ ++ D++VR+ +L+G + + C D HGTP+ A K
Sbjct: 4 KILVTSALPYANGSIHLGHMV-EHIQTDVWVRFQKLRGNECHYCCADDTHGTPVMLAAQK 62
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
+G +P +++ + E+ F I +D + T P + + SQ+ + NG + +V
Sbjct: 63 QGIAPEDMIAKVREEHLADFTGFFIGYDNYYSTHSPENKQFSQDIYRALKANGKIESRVI 122
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
+Q + +MFLPDRFV G CP C A+DQ GD CEVCG +P LINP A+ G
Sbjct: 123 EQLFDPEKQMFLPDRFVKGECPKCHAQDQYGDNCEVCGTTYSPTELINPYSAVSGAKPEL 182
Query: 183 RDSAHYYIKMQDFAERLKRWI---EKQPWKPNVK----NMVLSWIEEG----LEERAITR 231
R+S H++ K+ + A+ LK W KP+++ N + W+ EG L + I+R
Sbjct: 183 RESEHFFFKLGECADFLKAWTSGNNPHDGKPHLQAEALNKMKEWLGEGEETTLSDWDISR 242
Query: 232 DLNW-GIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTR 290
D + G +P D GK YVW +AP+GY++ RIG ++ +Y+ D QT
Sbjct: 243 DAPYFGFEIP----DAPGKYFYVWLDAPVGYMASFKNLCDRIGV--DFDEYF-KADSQTE 295
Query: 291 VIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRN 350
+ HFIGKD + FHA+FWPA L G P + A+ +LT++G+K S SR
Sbjct: 296 MYHFIGKDILYFHALFWPAMLHFSGH----------RAPTGVYAHGFLTVDGQKMSKSRG 345
Query: 351 WAIWVHEFLDV-FPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRAL 408
I +L+ +++RYY+ + + D D + DF R+N +LV N RA
Sbjct: 346 TFITAKSYLEQGLNPEWMRYYIAAKLNSKIEDIDLNLQDFISRVNSDLVGKYVNIAARAS 405
Query: 409 TFVNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNR 468
F+ + F+G + D D E L ++ + + E + + AL+ +M+LA N
Sbjct: 406 GFIAKRFEGRLK-----DVADSELLAKLTAQSEAIAECYESREYARALRDIMALADIVNE 460
Query: 469 YFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGIL---LEPFLPDASEKIWHLLNLDEVK 525
Y D +PW+ AK++ + + +++ A +L L P LP + LNL+ +
Sbjct: 461 YVDANKPWELAKQEG-QDARLHEVCSELINAFTMLTAYLAPVLPQTAANAAKFLNLEAIT 519
Query: 526 RWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRV 585
RE H + K E L ++V Q+ +D+I
Sbjct: 520 WANTRETLGKHAINKYEHLMQRVEQKQV--------------------------DDLIEA 553
Query: 586 AKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKL 645
K+ ++ + + E FDDF K+D+RV K++ + + KL
Sbjct: 554 NKQS--------IQTTPAPAAEESQYEKVAEQASFDDFMKIDMRVAKVLNCEAVEGSTKL 605
Query: 646 YVVKVDLGDEVRTLVAGL-KKYYKPEELLNRYVVVVANLEPKKLRGIG-SQGMLLAADDG 703
+D G E R + +G+ Y P EL R V+ VAN P+K+ G S+GM+L+A
Sbjct: 606 LKFDLDFGFEKRIIFSGIAASYPNPAELNGRMVIAVANFAPRKMAKFGVSEGMILSAATA 665
Query: 704 E-RVALLMPDKEVKLGAKV 721
+ ++ LL D + G KV
Sbjct: 666 DGKLKLLDVDAGAQPGDKV 684
>pir||A81246 methionyl-tRNA synthetase NMB0030 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225249|gb|AAF40501.1| (AE002361) methionyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 685
Score = 339 bits (860), Expect = 7e-92
Identities = 228/739 (30%), Positives = 359/739 (47%), Gaps = 78/739 (10%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VTSALPYANG IH GH+ ++ D++VR+ +L+G + C D HGTP+ A K
Sbjct: 4 KILVTSALPYANGSIHLGHMV-EHIQTDVWVRFQKLRGHACHYCCADDTHGTPVMLAAQK 62
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
+G +P +++ + E+ F I +D + T P + + SQ+ + NG + +V
Sbjct: 63 QGIAPEDMIAKVREEHLADFTGFFIGYDNYYSTHSPENKQFSQDIYRALKANGKIESRVI 122
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
+Q + +MFLPDRFV G CP C A+DQ GD CEVCG +P LINP A+ G
Sbjct: 123 EQLFDPEKQMFLPDRFVKGECPKCHAQDQYGDNCEVCGTTYSPTELINPYSAVSGTKPEL 182
Query: 183 RDSAHYYIKMQDFAERLKRWI---EKQPWKPNVK----NMVLSWIEEG----LEERAITR 231
R+S H++ K+ + A+ LK W KP+++ N + W+ EG L + I+R
Sbjct: 183 RESEHFFFKLGECADFLKAWTSGNNPHDGKPHLQAEALNKMKEWLGEGEETTLSDWDISR 242
Query: 232 DLNW-GIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTR 290
D + G +P D GK YVW +AP+GY++ RIG ++ +Y+ D QT
Sbjct: 243 DAPYFGFEIP----DAPGKYFYVWLDAPVGYMASFKNLCDRIGV--DFDEYF-KADSQTE 295
Query: 291 VIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRN 350
+ HFIGKD + FHA+FWPA L G P + A+ +LT++G+K S SR
Sbjct: 296 MYHFIGKDILYFHALFWPAMLHFSGH----------RAPTGVYAHGFLTVDGQKMSKSRG 345
Query: 351 WAIWVHEFLDV-FPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRAL 408
I +L+ +++RYY+ + + D D + DF R+N +LV N RA
Sbjct: 346 TFITAKSYLEQGLNPEWMRYYIAAKLNSKIEDIDLNLQDFISRVNSDLVGKYVNIAARAS 405
Query: 409 TFVNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNR 468
F+ + F+G + D D E L ++ + + E + + AL+ +M+LA N
Sbjct: 406 GFIAKRFEGRLK-----DVADSELLAKLTAQSEAIAECYESREYAKALRDIMALADIVNE 460
Query: 469 YFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGIL---LEPFLPDASEKIWHLLNLDEVK 525
Y D +PW+ AK++ + + +++ A +L L P LP + LNL+ +
Sbjct: 461 YVDANKPWELAKQEG-QDERLHEVCSELINAFTMLTAYLAPVLPQTAANAAKFLNLEAIT 519
Query: 526 RWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRV 585
R+ H + K E L ++V Q+ +D+I
Sbjct: 520 WANTRDTLGKHAINKYEHLMQRVEQKQV--------------------------DDLIEA 553
Query: 586 AKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKL 645
K+ A + K E FDDF K+D+RV K++ + + KL
Sbjct: 554 NKQSIAAAAAPAAE--------EGKYEKVAEQASFDDFMKIDMRVAKVLNCEAVEGSTKL 605
Query: 646 YVVKVDLGDEVRTLVAGL-KKYYKPEELLNRYVVVVANLEPKKLRGIG-SQGMLLAADDG 703
+D G E R + +G+ Y P EL R V+ VAN P+K+ G S+GM+L+A
Sbjct: 606 LKFDLDFGFEKRIIFSGIAASYPNPAELNGRMVIAVANFAPRKMAKFGVSEGMILSAATA 665
Query: 704 E-RVALLMPDKEVKLGAKV 721
+ ++ LL D + G KV
Sbjct: 666 DGKLKLLDVDTGAQPGDKV 684
>sp|P23920|SYM_BACST METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|98214|pir||S16682 methionine--tRNA ligase (EC
6.1.1.10) - Bacillus stearothermophilus
>gi|39989|emb|CAA40999.1| (X57925) methionyl-tRNA
synthetase [Bacillus stearothermophilus]
Length = 649
Score = 324 bits (823), Expect = 2e-87
Identities = 221/736 (30%), Positives = 355/736 (48%), Gaps = 109/736 (14%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ +T+ + Y + +H GH A + D RY RL+G DV+++ GTDEHG I +A ++
Sbjct: 6 FYLTTPIYYPSDKLHIGH-AYTTVAGDAMARYKRLRGYDVMYLTGTDEHGQKIQRKAQEK 64
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
G +P++ VD+ I+ +++ IS+D F RT H K+ ++ F + E G +
Sbjct: 65 GVTPQQYVDDIVAGIQELWRKLDISYDDFIRTTQERHKKIVEKIFARLVEQGDI------ 118
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y G + +G C C T L++ C CGRP+
Sbjct: 119 ---------------------YLG--EYEGWYCTPCESFYTERQLVDGNCPDCGRPVEKV 155
Query: 184 DSAHYYIKMQDFAERLKRWIEKQPW----KPNVKNMVLSWIEEGLEERAITRD-LNWGIP 238
Y+ +M + +RL ++ E+ P + M+ ++I+ GLE+ A++R +WGI
Sbjct: 156 KEESYFFRMSKYVDRLLQYYEENPDFIQPESRKNEMINNFIKPGLEDLAVSRTTFDWGIK 215
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNE--WKKYWLNIDGQTRVIHFIG 296
VP D + V+YVW +A YI+ G N+ ++KYW +H +G
Sbjct: 216 VPGDPKH----VIYVWIDALANYITAL-----GYGTDNDEKFRKYW------PADVHLVG 260
Query: 297 KDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVH 356
K+ + FH I+WP LMA G LP + + +L ++ K S S+ +
Sbjct: 261 KEIVRFHTIYWPIMLMALGL----------PLPKKVFGHGWLLMKDGKMSKSKGNVVDPV 310
Query: 357 EFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFD 416
+D + D LRYYL +P D F+ F RIN +L N+LGN +HR + + +YF
Sbjct: 311 MIIDRYGLDALRYYLLREVPFGSDGVFTPEGFIERINYDLANDLGNLLHRTVAMIEKYFG 370
Query: 417 GVVPE-RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQP 475
G +P RG DR+ E + ++ E + F AL V L N+Y D QP
Sbjct: 371 GAIPPYRGPKTPFDRDLSETAREVVRQYEEAMERMEFSVALSAVWQLIGRTNKYIDETQP 430
Query: 476 WKTAKEDKVRTGTTVNISLQIVKAL---GILLEPFLPDASEKIWHLLNLDE--VKRW--- 527
W AKE+ R ++ + ++L +LL+PFL E+I+ L + + +K W
Sbjct: 431 WVLAKEESKRE-ELASVMAHLAESLRYTAVLLQPFLTRTPERIFTQLGISDRSLKEWDSL 489
Query: 528 -EFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVA 586
+F +P G V+K E LF ++ + +I +M G P A A
Sbjct: 490 YDFGLIPEGTNVQKGEPLFPRLDIGVEVEYIKAHMQGGKPAEA----------------A 533
Query: 587 KEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLY 646
KE EK+ + + DDFAK+DLRV ++++ + NADKL
Sbjct: 534 KE--------------------EKQAARAEEISIDDFAKVDLRVAEVVQPERMKNADKLL 573
Query: 647 VVKVDLGDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERV 706
+++DLG E R +++G+ ++YKPEEL+ + V+ VANL+P KLRG S+GM+LA G
Sbjct: 574 KLQLDLGGEKRQVISGIAEFYKPEELIGKKVICVANLKPAKLRGEWSEGMILAGGSGGGF 633
Query: 707 ALLMPDKEVKLGAKVR 722
+L D+ V G K++
Sbjct: 634 SLATVDQHVPNGTKIK 649
>pdb|1QQT|A Chain A, Methionyl-Trna Synthetase From Escherichia Coli
Length = 551
Score = 323 bits (818), Expect = 6e-87
Identities = 186/556 (33%), Positives = 285/556 (50%), Gaps = 27/556 (4%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VT ALPYANG IH GH+ ++ AD++VRY R++G +V FIC D HGTPI +A +
Sbjct: 6 KILVTCALPYANGSIHLGHML-EHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQ 64
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P +++ E ++ + F IS+D + T + +LS+ + + ENG + +
Sbjct: 65 LGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTI 124
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q Y MFLPDRFV GTCP C + DQ GD CEVCG +P LI P+ + G
Sbjct: 125 SQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVM 184
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNW-GIPVPL 241
RDS H++ + F+E L+ W + V N + W E GL++ I+RD + G +P
Sbjct: 185 RDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIP- 243
Query: 242 DEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIP 301
+ GK YVW +APIGY+ + G + +YW D + HFIGKD +
Sbjct: 244 ---NAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKK-DSTAELYHFIGKDIVY 299
Query: 302 FHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV 361
FH++FWPA L + + P ++ + Y+T+ G K S SR I +L+
Sbjct: 300 FHSLFWPAMLEG----------SNFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNH 349
Query: 362 FPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVP 420
F AD LRYY T + D D + DF R+N ++VN + N R F+N+ FDGV+
Sbjct: 350 FDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLA 409
Query: 421 ERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAK 480
+ D + A + +GE + F A++ +M+LA NRY D + PW AK
Sbjct: 410 S----ELADPALYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAK 465
Query: 481 E--DKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP-AGHK 537
+ ++ + + + L L+P LP +E+ LN + W+ + P GHK
Sbjct: 466 QAGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTE--LTWDGIQQPLLGHK 523
Query: 538 VRKPEILFKKVTDDQI 553
V + L+ ++ Q+
Sbjct: 524 VNPFKALYNRIDMRQV 539
>sp|O33925|SYM_THEMA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437661|pir||E72297 methionine--tRNA ligase (EC
6.1.1.10) - Thermotoga maritima (strain MSB8)
>gi|2645225|gb|AAB87143.1| (U76417) methionyl-tRNA
synthetase [Thermotoga maritima]
>gi|4981630|gb|AAD36162.1|AE001768_11 (AE001768)
methionyl-tRNA synthetase [Thermotoga maritima]
Length = 629
Score = 316 bits (801), Expect = 6e-85
Identities = 226/729 (31%), Positives = 348/729 (47%), Gaps = 110/729 (15%)
Query: 2 VRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
+++ +T+ + Y N H G A + ADI RY R G DV F+ GTDEHG + A
Sbjct: 1 MKFYITTPIYYVNSEPHIGS-AYTTIVADIIARYKRFMGYDVFFLTGTDEHGQKVLQAAQ 59
Query: 62 KEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKV 121
+ G+ P+E DE E+ K ++ KI+ D+F RT +H K QEF K ENG + K +
Sbjct: 60 QAGKDPQEFCDELAEKFKRLWKELKITNDYFIRTTDEMHMKTVQEFVAKMKENGDVYKGI 119
Query: 122 TKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPIS 181
K YC + F + VI ++G++ C C RP+
Sbjct: 120 YKGWYCVPCETFWNEDEVI----------KEGEE---------------RFCPECKRPVK 154
Query: 182 FRDSAHYYIKMQDFAERLKRWIEKQP--WKPNV-KNMVLSWIEEGLEERAITR-DLNWGI 237
+ + +Y+ ++ + + L ++ E+ P +P+ +N +L +E GL++ +ITR WG+
Sbjct: 155 WVEEENYFFRLSKYRDSLLKYYEEHPDFVEPDFRRNEMLKILEGGLKDLSITRTTFKWGV 214
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
P+ D E V+YVW +A I YIS G +E W D +H IGK
Sbjct: 215 PMKDDPE----HVIYVWVDALINYISAI-----GYGWNDEMFNKWWPAD-----LHLIGK 260
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHE 357
+ FH+I WPA LM+ G LP + A+ +LT+ G+K S S AI
Sbjct: 261 EINRFHSIIWPAMLMSVG----------LPLPKKVFAHGWLTVNGQKISKSLGNAIDPRF 310
Query: 358 FLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
F+ + D +RYYL + +D DFS R+N +L N+ GN +HR + +YF+G
Sbjct: 311 FVKRYGNDVVRYYLIRDIMFGKDGDFSEERLVHRLNSDLANDYGNLLHRITAMIKKYFNG 370
Query: 418 VVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
+P + D E + EL+ +YR +AL ++ + N+YF+ +PW
Sbjct: 371 RLPSPSAQEGFDSWLKERFFETKDAYHELMDSYRLTEALDKIWEFIADVNKYFNDTKPWI 430
Query: 478 TAKEDKV-RTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRE----L 532
KE + R GT + SL+ V + ++ P +PD SE+++ ++ +E E E L
Sbjct: 431 LGKEGNMERLGTVLYNSLEAVFKVALMTLPVMPDTSEEVFRRVSFEEKPSKEHLENWGVL 490
Query: 533 PAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGD 592
G V E LFKK+ + A+ N I +D + K
Sbjct: 491 KPGSTVIHGEPLFKKIDAKDFKKVVETVSAEQN----AITIDDFSK-------------- 532
Query: 593 EAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDL 652
+DLR+ K++E + PN+ KL + +DL
Sbjct: 533 ---------------------------------VDLRIAKVLEAEKVPNSRKLLRLIIDL 559
Query: 653 GDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPD 712
G E R +VAG+ ++Y+PEEL+ + +VVVANL+P KL GI SQGMLLAA G+ + LL D
Sbjct: 560 GTEKRQIVAGIAEHYRPEELVGKLIVVVANLKPAKLMGIESQGMLLAAKSGDTLRLLTVD 619
Query: 713 KEVKLGAKV 721
E+ GAKV
Sbjct: 620 GEITPGAKV 628
>dbj|BAB03772.1| (AP001507) methionyl-tRNA synthetase [Bacillus halodurans]
Length = 660
Score = 297 bits (753), Expect = 2e-79
Identities = 207/733 (28%), Positives = 354/733 (48%), Gaps = 94/733 (12%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ +T+ + Y + +H GH A + D RY RL+G +V+++ GTDEHG I +A +
Sbjct: 8 FYLTTPIYYPSDKLHIGH-AYTTVAGDAMARYKRLRGYNVMYLTGTDEHGQKIEQKAEAK 66
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
G +P++ VDE I+ +++ IS+D F RT H K+ Q+ F + + G + +
Sbjct: 67 GLTPKQFVDEIVSGIQDLWKKLDISYDDFIRTTEERHIKVVQQIFEQLLDQGDIYLGDYE 126
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y D+ F + ++ D G+ LI + G P+
Sbjct: 127 GWYSIPDETFYTETQLVDK-----EYDADGN-------------LIGGKSPDSGHPVEKV 168
Query: 184 DSAHYYIKMQDFAERLKRWIEKQPW----KPNVKNMVLSWIEEGLEERAITR-DLNWGIP 238
Y+ +M +A+RL ++ E+ P + M+ ++I+ GLE+ A++R WG+P
Sbjct: 169 REQSYFFRMSKYADRLLQFYEENPQFIQPESRKNEMINNFIKPGLEDLAVSRTSFTWGVP 228
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKD 298
VP D + V+YVW +A YI+ + +++ YW +H +GK+
Sbjct: 229 VPRDPK----HVVYVWIDALSNYITAL---GYGSDQQEKYENYW------PADVHLVGKE 275
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
+ FH I+WP LMA + LP + + +L ++ K S S+ +
Sbjct: 276 IVRFHTIYWPIMLMA----------LDLPLPKKVFGHGWLLMKDGKMSKSKGNVVDPVPL 325
Query: 359 LDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV 418
+D + D LRYYL +P D F+ F R+N +L N+LGN ++R + + +YFDG
Sbjct: 326 IDRYGLDALRYYLLREVPFGSDGVFTPEAFVERVNYDLANDLGNLLNRTVAMIEKYFDGK 385
Query: 419 VPER-GELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
+P + D + +E + K+V + + F AL + L S N+Y D QPW
Sbjct: 386 IPSYVKDGTPFDADLVELVYSTVKKVEDAMEEMEFSIALTAIGQLISRTNKYIDETQPWV 445
Query: 478 TAKEDKVR--TGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLD-EVKRWE----FR 530
AK++ R G + + ++ + +LL+PF+ A +KIW L +D + WE F
Sbjct: 446 LAKDESKREQLGAAMYHLAESIRYVSVLLQPFMTKAPQKIWEQLGIDSSLTTWESLETFG 505
Query: 531 ELPAGHKVRKPEILFKKVTDDQIIYFILNYM-AKGNPEGARILLDKYYKREDVIRVAKEK 589
++P V+K + LF ++ ++ + I + M PE A
Sbjct: 506 QIPGNTNVQKGQPLFPRLDVEEEVAHIKSLMGGSKKPEEAP------------------- 546
Query: 590 FGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVK 649
KD EK+E E + DDF+K++LR+ ++I+ + AD+L ++
Sbjct: 547 -------------KD----EKEESDE--ITIDDFSKVELRIAEVIDAEPVKKADRLLKIQ 587
Query: 650 VDLGDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALL 709
+DLG E R +V+G+ KYY P +L+ + V+ V NL+P KLRG SQGM+LA +G+++ L
Sbjct: 588 LDLGYEKRQVVSGIAKYYSPSDLIGKKVICVTNLKPVKLRGELSQGMILAGSEGDQLRLA 647
Query: 710 MPDKEVKLGAKVR 722
D + G+ V+
Sbjct: 648 TVDGALPNGSLVK 660
>sp|P57210|SYM_BUCAI METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|10038793|dbj|BAB12828.1| (AP001118) methionyl-tRNA
synthetase [Buchnera sp. APS]
Length = 547
Score = 283 bits (717), Expect = 4e-75
Identities = 179/563 (31%), Positives = 283/563 (49%), Gaps = 34/563 (6%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VT ALPYANG IH GH+ ++ ADI+VRY R++G +V F+ D HGT I +A
Sbjct: 7 KILVTCALPYANGSIHIGHML-EHIQADIWVRYHRMRGHEVWFVSADDAHGTAIMLKAQD 65
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
SP +++ + +I F KIS D + T + LS++ F E G + +K
Sbjct: 66 LEISPNKLIKNIRIEHQIDFSNFKISHDNYYSTHSLENLYLSRKIFTCLNEKGLIKEKKI 125
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q Y K+FLPDRF+ GTCP C +++Q GD CE+C P LINP I G+
Sbjct: 126 FQLYDTVKKIFLPDRFIKGTCPICKSKNQYGDNCEICSATYEPTDLINPISVISGKKPIL 185
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNW-GIPVPL 241
+++ H Y + F LK+WI + +V W + GL+ AI+RD + G +P
Sbjct: 186 KNTKHLYFDLPSFTNMLKKWIHSGVLEESVIKKTEEWFKVGLKSWAISRDAPYFGFKIP- 244
Query: 242 DEEDMKGKVLYVWFEAPIGYISITIEHFKRI---GKPNEWKKYWLNIDGQTRVIHFIGKD 298
+ K YVW +APIGYIS FK + K + + W N + + HFIGKD
Sbjct: 245 ---NYPNKYFYVWLDAPIGYISA----FKNLCFKSKKLNFNELW-NQNSNYELYHFIGKD 296
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
I FH +FWPA L A + P I + +LT+ G K S SR I ++
Sbjct: 297 IIYFHTLFWPAILEA----------VSFRQPSGIFVHGHLTMNGLKLSKSRGALIKASDW 346
Query: 359 LDVFPADYLRYYLTT-IMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
+ F +D LRYY + + +T D + + DF +IN ++VN L N R +F+N+YF+G
Sbjct: 347 IQYFDSDSLRYYYASKLSNKTHDIEINLEDFIQKINSDIVNKLVNLAARNASFINKYFNG 406
Query: 418 VVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
+ ++ L + + + + + N F +K M L N+Y + K+PWK
Sbjct: 407 YLSDK--LSNI--KLYKYFVNTSSSIEDFFENREFSFIVKESMRLLDVANQYINEKKPWK 462
Query: 478 TAK-EDKVRTGTTV-NISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP-A 534
+ E+ +R + + + + + + I L+P +PD + K L W+ + P
Sbjct: 463 IKRTEENIRELQNICTMGINLFRIIMIFLKPIVPDLAIKTESF--LISKLTWDGIKKPLL 520
Query: 535 GHKVRKPEILFKKVTDDQIIYFI 557
H++ K L+K++ +++ F+
Sbjct: 521 SHQINKFFPLYKRIDVEKMFEFM 543
>sp|P37465|SYM_BACSU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|2127140|pir||S66067 methionine--tRNA ligase (EC
6.1.1.10) metS - Bacillus subtilis
>gi|467427|dbj|BAA05273.1| (D26185) methionyl-tRNA
synthetase [Bacillus subtilis]
>gi|2632305|emb|CAB11814.1| (Z99104) methionyl-tRNA
synthetase [Bacillus subtilis]
Length = 664
Score = 280 bits (710), Expect = 3e-74
Identities = 208/738 (28%), Positives = 357/738 (48%), Gaps = 100/738 (13%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ +T+ + Y +G +H GH A + D RY RLKG DV ++ GTDEHG I +A +E
Sbjct: 8 FYITTPIYYPSGKLHIGH-AYTTVAGDAMARYKRLKGFDVRYLTGTDEHGQKIQQKAEQE 66
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
+P+E VD I+ +++ +IS D F RT H + ++ F K +NG + +
Sbjct: 67 NITPQEYVDRAAADIQKLWKQLEISNDDFIRTTEKRHKVVIEKVFQKLLDNGDIYLDEYE 126
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y D+ F + ++ ++KG+ +I + G P+
Sbjct: 127 GWYSIPDETFYTETQLVDI-----ERNEKGE-------------VIGGKSPDSGHPVELI 168
Query: 184 DSAHYYIKMQDFAERLKRWIEKQPW----KPNVKNMVLSWIEEGLEERAITRD-LNWGIP 238
Y+ +M +A+RL ++ E+ P + M+ ++I+ GLE+ A++R +WG+
Sbjct: 169 KEESYFFRMGKYADRLLKYYEENPTFIQPESRKNEMINNFIKPGLEDLAVSRTTFDWGVK 228
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNE----WKKYWLNIDGQTRVIHF 294
VP + + V+YVW +A Y++ +G E ++KYW +H
Sbjct: 229 VPENPKH----VVYVWIDALFNYLTA-------LGYDTENDELYQKYW------PADVHL 271
Query: 295 IGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIW 354
+GK+ + FH I+WP LMA + LP + A+ +L ++ K S S+ +
Sbjct: 272 VGKEIVRFHTIYWPIMLMAL----------DLPLPKQVFAHGWLLMKDGKMSKSKGNVVD 321
Query: 355 VHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRY 414
++ + D LRYYL +P D F+ F RIN +L N+LGN ++R + +N+Y
Sbjct: 322 PVTLIERYGLDELRYYLLREVPFGSDGVFTPEGFVERINYDLANDLGNLLNRTVAMINKY 381
Query: 415 FDGVVPE-RGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHK 473
FDG + +G + E D E+ K + + N F AL + L S N+Y D
Sbjct: 382 FDGQIGSYKGAVTEFDHTLTSVAEETVKAYEKAMENMEFSVALSTLWQLISRTNKYIDET 441
Query: 474 QPWKTAKEDKVRTGTTVNISLQIVKAL---GILLEPFLPDASEKIWHLLNL--DEVKRWE 528
PW AK D + ++ + ++L +LL+PFL EK++ L + + +K W+
Sbjct: 442 APWVLAK-DPAKEEELRSVMYHLAESLRISAVLLQPFLTKTPEKMFEQLGITDESLKAWD 500
Query: 529 ----FRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIR 584
F +L KV+K E LF ++ ++ I +I KG +G+
Sbjct: 501 SITAFGQLK-DTKVQKGEPLFPRLEAEEEIAYI-----KGKMQGSA-------------- 540
Query: 585 VAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADK 644
AKE+ +E + R+ + + D F ++LRV ++IE + AD+
Sbjct: 541 PAKEETKEEEPQEVDRLPE--------------ITIDQFMDVELRVAEVIEAEPVKKADR 586
Query: 645 LYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGE 704
L +++DLG E R +V+G+ K+Y PEEL+ + +V V NL+P KLRG SQGM+LA +
Sbjct: 587 LLKLQLDLGFEKRQVVSGIAKHYTPEELVGKKLVCVTNLKPVKLRGELSQGMILAGEADG 646
Query: 705 RVALLMPDKEVKLGAKVR 722
+ ++ D+ + G +++
Sbjct: 647 VLKVVSIDQSLPKGTRIK 664
>sp|P23395|SYM_THETH METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|68543|pir||SYTWMT methionine--tRNA ligase (EC
6.1.1.10) - Thermus aquaticus >gi|155136|gb|AAA27510.1|
(M64273) transfer RNA-Met synthetase [Thermus
thermophilus]
Length = 616
Score = 280 bits (708), Expect = 5e-74
Identities = 211/734 (28%), Positives = 332/734 (44%), Gaps = 143/734 (19%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ VT+ + Y N H GH A + AD R+ RL G F+ GTDEHG + A
Sbjct: 5 FYVTTPIYYVNAEPHLGH-AYTTVVADFLARWHRLDGYRTFFLTGTDEHGETVYRAAQAA 63
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
G P+ VD + K + I++D F RT H K+ Q K YE G +
Sbjct: 64 GEDPKAFVDRVSGRFKRAWDLLGIAYDDFIRTTEERHKKVVQLVLKKVYEAGDIY----- 118
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y E++ ++ C C R T + L+ C I GRP+ R
Sbjct: 119 --YGEYEGLY----------------------CVSCERFYTEKELVEGLCPIHGRPVERR 154
Query: 184 DSAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEGLEERAITRD---LNWGI 237
+Y+ +M+ + L+ +I++ P +N VL+ + E + + +I+R + WGI
Sbjct: 155 KEGNYFFRMEKYRPWLQEYIQENPDLIRPEGYRNEVLAMLAEPIGDLSISRPKSRVPWGI 214
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
P+P DE V YVWF+A + Y+S +++ + W W H IGK
Sbjct: 215 PLPWDE----NHVTYVWFDALLNYVS-ALDYPEGEAYRTFWPHAW----------HLIGK 259
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTL-------EGKKFSTSRN 350
D + HA+FWP L A G IP +L + +G+K S +
Sbjct: 260 DILKPHAVFWPTMLKAAG----------------IPMYRHLNVGGFLLGPDGRKMSKTLG 303
Query: 351 WAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTF 410
+ L+ + D LRYYL +P +D+ S + R +L ++LGN V R
Sbjct: 304 NVVDPFALLEKYGRDALRYYLLREIPYGQDTPVSEEALRTRYEADLADDLGNLVQRTRAM 363
Query: 411 VNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYF 470
+ R+ +G +PE + E L E + L+ +F AL+ M+ NRY
Sbjct: 364 LFRFAEGRIPE-----PVAGEELAEGTGLAGRLRPLVRELKFHVALEEAMAYVKALNRYI 418
Query: 471 DHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLL------NLDEV 524
+ K+PW+ K++ + ++ ++ ILL P +PD ++ L L+E
Sbjct: 419 NEKKPWELFKKEPEEARAVLYRVVEGLRIASILLTPAMPDKMAELRRALGLKEEVRLEEA 478
Query: 525 KRWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIR 584
+RW E + PE A +L K
Sbjct: 479 ERWGLAE------------------------------PRPIPEEAPVLFPK--------- 499
Query: 585 VAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADK 644
EA+V + K K+E ++ +DFAK++LRV +++ + HPNAD+
Sbjct: 500 -------KEAKV---------EAKPKEEA---WIGIEDFAKVELRVAEVLAAEKHPNADR 540
Query: 645 LYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGE 704
L V+++ LG+E RT+V+G+ K+Y+PEEL+ + VV+VANL+P KLRGI SQGM+LAA +GE
Sbjct: 541 LLVLRLSLGNEERTVVSGIAKWYRPEELVGKKVVLVANLKPAKLRGIESQGMILAAQEGE 600
Query: 705 RVALLMPDKEVKLG 718
+AL+ + EV G
Sbjct: 601 ALALVTVEGEVPPG 614
>pir||F81356 methionine--tRNA ligase (EC 6.1.1.10) Cj0838c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968284|emb|CAB73103.1| (AL139076) methionyl-tRNA
synthetase [Campylobacter jejuni]
Length = 628
Score = 273 bits (692), Expect = 4e-72
Identities = 197/725 (27%), Positives = 342/725 (47%), Gaps = 103/725 (14%)
Query: 2 VRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
+RY +T+ + Y N H GH A + AD R+ RL+G + F+ GTDEHG I A
Sbjct: 1 MRY-ITTPIYYVNDVPHLGH-AYTTIIADTLARFYRLQGHETRFLTGTDEHGQKIEEAAK 58
Query: 62 KEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKV 121
+P+E D+ + K + +I++D + RT H + + FLK ++ G + K
Sbjct: 59 LRNSTPQEYADKISFEFKKLWDEFEITYDIYARTTDTRHIEFIKAMFLKMWQKGDIYKDE 118
Query: 122 TKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPIS 181
+ YC + F +I C C CG+
Sbjct: 119 YEGHYCISCESFFTQSQLINDCS----------------------------CPDCGKQTR 150
Query: 182 FRDSAHYYIKMQDFAERLKRWIE-KQPWKP-NVKNMVLSWIEEGLEERAITR-DLNWGIP 238
Y+ K+ + +++ +W E K P P N KN ++++++ GL++ +ITR +WGI
Sbjct: 151 ILKEESYFFKLSKYQDKILQWYEEKDPILPKNKKNELINFVQNGLKDLSITRTSFDWGIK 210
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKD 298
+P + D K ++YVW +A Y+S F+ G E K+W +H +GKD
Sbjct: 211 LPQEINDDK-HIIYVWLDALFIYVSSL--DFQNKG---ENAKFW------PAHVHLVGKD 258
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
+ FHAI+WPAFLM+ + LP I A+ + T EG+K S S+ + E
Sbjct: 259 ILRFHAIYWPAFLMS----------VDLPLPKFIGAHGWWTKEGEKMSKSKGNVVKPKEV 308
Query: 359 LDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV 418
+D + ++ RY+L +P D DFS + RIN EL N GN ++R + +Y G
Sbjct: 309 VDAYGSEAFRYFLLREVPFGNDGDFSENMLINRINAELSNEFGNLLNRIIGMSTKYSQGN 368
Query: 419 VPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKT 478
+ + G L + E L + ++ E + N + L+ + S N +PW
Sbjct: 369 ISKEGVLKFYNAE-LNQAKEHLNLAVEFLENLQCNRYLEELFKALSVANLAISKYEPWSL 427
Query: 479 AKEDK-VRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHK 537
KE+K + V + I+ +LL P LP +S+K+ LN E+ +
Sbjct: 428 IKENKHEQANALVALCANILAKTSLLLSPTLPKSSQKVALALNF-EISSANYT------- 479
Query: 538 VRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVV 597
K + D++++ F K NP + F + +
Sbjct: 480 --------KMILDNELLDF------KANP-------------------CEALFPKVEKAL 506
Query: 598 LRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGD-EV 656
L++ K+ E K+ + +K DDFAK++++V K+++ ++ ++KL +++L D E+
Sbjct: 507 LKQEIKE----EPKKEESPKIKIDDFAKIEIKVAKVLDCQNIEGSEKLLKFQLELDDKEI 562
Query: 657 RTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVK 716
R +++G+ KYYK +L+ + V V++NL+ K+ G S GM+L+A G+++ L+ P++ V+
Sbjct: 563 RQVLSGIAKYYKASDLIGKQVCVISNLKKAKIFGHESDGMILSAKSGDKLVLIAPEQLVQ 622
Query: 717 LGAKV 721
G+ V
Sbjct: 623 NGSLV 627
>pir||C75395 methionyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459194|gb|AAF11005.1|AE001988_1 (AE001988)
methionyl-tRNA synthetase [Deinococcus radiodurans]
Length = 681
Score = 269 bits (681), Expect = 7e-71
Identities = 211/738 (28%), Positives = 331/738 (44%), Gaps = 95/738 (12%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ +T+A+ YANG H GH+ L AD RY RL G DV F+ GTDEHG IS A K
Sbjct: 20 FFITAAIDYANGTPHIGHVYEKIL-ADAIARYQRLAGRDVTFVMGTDEHGEKISKAAAKG 78
Query: 64 GRSPREIVDEFHEQ-IKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P+E+VD+ E+ + +++ IS+DFF RT H K Q+ + Y+ G +
Sbjct: 79 GVTPQELVDDLSERAFQGLWKKLGISYDFFIRTTSAKHKKYVQDVLQRVYDAGDIYFAEY 138
Query: 123 KQAYCEHDKMFLPDRFVI----GTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGR 178
+ Y + ++ ++ ++ G + G +D
Sbjct: 139 EGLYSVGAERYVTEKELVEGPDGVRRFPGDKD---------------------------- 170
Query: 179 PISFRDSAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEGLEERAITRD--- 232
P R A+Y+ MQ + L +++ P +N VL ++E + +I+R
Sbjct: 171 PPELRREANYFFNMQKYQPWLLETLQQNPDLIQPAGYRNEVLEMLKEDIGPLSISRPKAR 230
Query: 233 LNWGIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVI 292
+ WGI +P D + V YVWF+A + Y++ + + K W
Sbjct: 231 VPWGIELPWDTDH----VTYVWFDALLSYLTPLVSQGQDASMSG---KAW---------- 273
Query: 293 HFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWA 352
H IGKD + HA+FWP L A G + + + L +G+K S A
Sbjct: 274 HVIGKDILKPHAVFWPTMLRAAGLPLYRRL---------VVHSHILAEDGRKMGKSLGNA 324
Query: 353 IWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVN 412
I E + +P D +RY L DS F R+N +L N+LGN + R ++ +
Sbjct: 325 IDPEELVAAWPVDAIRYALLREASLGADSPFGEGVLVSRLNSDLANDLGNLLSRTVSMIQ 384
Query: 413 RYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDH 472
+Y GV+P E + +RE EV L+ + A+ MS NRY
Sbjct: 385 KYRGGVIPAATEPTDREREIEAAARALPDEVLRLVDELKINMAIDAAMSFVRDLNRYIAE 444
Query: 473 KQPWKTAK--EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDE-----VK 525
PW AK E + R T + + + ++ + LE +P ++++ L L
Sbjct: 445 STPWTLAKSPETQGRLDTVLYTAAEGLRVASVALEAVIPTKAKELREQLGLGRQGYPLQA 504
Query: 526 RWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRV 585
W PAG +V+ ILF K P+ + + +
Sbjct: 505 AWGL--TPAGTRVQGGAILF----------------PKPEPKADETKNAEAKPPKPQAKK 546
Query: 586 AKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKL 645
K+ D A + + +G + DDFAK+DLR+ +++ + ADKL
Sbjct: 547 EKKTVTDTAPAKTTEQKPEAAAPAQNDG---LISIDDFAKIDLRIAEVVACEAVEKADKL 603
Query: 646 YVVKVDLGDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAA-DDGE 704
+ V LGDE RT+V+G++K+Y+PE L+ R VV+VANL+P KLRGI SQGM+LAA DD
Sbjct: 604 LKLTVKLGDETRTVVSGIRKWYEPEALVGRKVVLVANLKPAKLRGIESQGMILAAEDDAG 663
Query: 705 RVALLMPDKEVKLGAKVR 722
+ L+ + ++ G KVR
Sbjct: 664 NLDLVGTELDLPSGTKVR 681
>emb|CAA89153.1| (Z49216) mitoxantrone-resistance associated gene [Homo sapiens]
Length = 478
Score = 250 bits (633), Expect = 3e-65
Identities = 155/479 (32%), Positives = 248/479 (51%), Gaps = 51/479 (10%)
Query: 168 LINPRCAICGRPISFRDSAHYYIKMQDFAERLKRWIEK----QPWKPNVKNMVLSWIEEG 223
L P+C +C + S H ++ + +RL+ W+ + W PN + + SW+ +G
Sbjct: 8 LKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQFITRSWLRDG 67
Query: 224 LEERAITRDLNWGIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWL 283
L+ R ITRDL WG PVPL E + KV YVWF+A IGY+SIT + ++W+++W
Sbjct: 68 LKPRCITRDLKWGTPVPL--EGFEDKVFYVWFDATIGYLSITANY------TDQWERWWK 119
Query: 284 NIDGQTRVIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGK 343
N + Q + F+ KDN+PFH++ +P + E + L + A EYL E
Sbjct: 120 NPE-QVDLYQFMAKDNVPFHSLVFPCSALG--------AEDNYTLVSHLIATEYLNYEDG 170
Query: 344 KFSTSRNWAIWVHEFLDV-FPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGN 402
KFS SR ++ D PAD R+YL I PE +DS FS++D ++ N EL+NNLGN
Sbjct: 171 KFSKSRGVGVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGN 230
Query: 403 FVHRALTFVNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSL 462
F++RA FV+++F G VPE L D+ L + + +L+ R +DAL+ ++++
Sbjct: 231 FINRAGMFVSKFFGGYVPEM-VLTPDDQRLLGHVTLELQHYHQLLEKVRIRDALRSILTI 289
Query: 463 ASFGNRYFDHKQPWKTAK---EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLL 519
+ GN+Y +PWK K D+ R GT +++ I L ++L+P++P S I L
Sbjct: 290 SRHGNQYIQVNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQL 349
Query: 520 NLD----EVKRWEFR-ELPAGHKVRKPEILFKKVTDDQIIYF----------------IL 558
L + F LPAGH++ LF+K+ +DQI ++
Sbjct: 350 QLPPPACSILLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVV 409
Query: 559 NYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEK---KEGK 614
+ P+ + L+D+ K+ +++R K + D+ EV V K + LK++ EGK
Sbjct: 410 ETVTTAKPQQIQALMDEVTKQGNIVRELKAQKADKNEVA-AEVAKLLDLKKQLAVAEGK 467
>sp|Q9ZKG9|SYM_HELPJ METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437662|pir||H71867 methionine--tRNA ligase (EC
6.1.1.10) - Helicobacter pylori (strain J99)
>gi|4155547|gb|AAD06543.1| (AE001525) METHIONYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 656
Score = 242 bits (610), Expect = 1e-62
Identities = 199/732 (27%), Positives = 326/732 (44%), Gaps = 88/732 (12%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M + ++T+ + Y N H GH A L AD +Y L+GE+V F+ GTDEHG I A
Sbjct: 1 MQKSLITTPIYYVNDIPHIGH-AYTTLIADTLKKYYTLQGEEVFFLTGTDEHGQKIEQSA 59
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
+SP+ D K + + +D F RT H K Q F +E G + K
Sbjct: 60 RLRNQSPKAYADSISAIFKNQWDFFNLDYDGFIRTTDSEHQKCVQNAFEIMFEKGDIYKG 119
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
YC + YC +V C C R
Sbjct: 120 TYSGYYC------------VSCESYCAVSKVDNTDSKVL-------------CPDCLRET 154
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEGLEERAITR-DLNWG 236
+ + Y+ K+ + + L + K P KN V S+IE+GL + +ITR WG
Sbjct: 155 TLLEEESYFFKLSAYEKPLLEFYAKNPEAILPIYRKNEVTSFIEQGLLDLSITRTSFEWG 214
Query: 237 IPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIG 296
IP+P D K V+YVW +A + Y S +G N + + R H +G
Sbjct: 215 IPLPKKMNDPK-HVVYVWLDALLNYAS-------ALGYLNGLDNKMAHFE---RARHIVG 263
Query: 297 KDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPY--DIPANEYLTLEGKKFSTSRNWAIW 354
KD + FHAI+WPAFLM+ NLP + + + T+EG K S S +
Sbjct: 264 KDILRFHAIYWPAFLMSL------------NLPLFKQLCVHGWWTIEGVKMSKSLGNVLD 311
Query: 355 VHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRY 414
+ + + LRY+L +P +D DFS RIN L N+LGN ++R L +Y
Sbjct: 312 AQKLAMEYGIEELRYFLLREVPFGQDGDFSKKALVERINANLNNDLGNLLNRLLGMAKKY 371
Query: 415 FDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQ 474
F+ + + ++ + LE+ + + + AL+ + ++ F N+ ++
Sbjct: 372 FNYSL-KSTKITAYYPKELEKAHQILDNANSFVPKMQLHKALEELFNIYDFLNKLIAKEE 430
Query: 475 PWKTAK-EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP 533
PW K + + +++ + LL F+P ++ K+ ++ R
Sbjct: 431 PWVLHKNNESEKLEALLSLIANTLLQSSFLLYAFMPKSAMKLASAFRVEITPNNYERFFK 490
Query: 534 AGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDE 593
A KK+ D M + E ++K K E + ++ K + G+E
Sbjct: 491 A-----------KKLQD----------MVLQDTEPLFSKIEKIEKIEKIEKIEKIEKGEE 529
Query: 594 AEVVLRRVYKDIKLKEKKEG---KEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKV 650
A + + + KEK++ +E Y+ +DF K++++VG I E + ++KL +KV
Sbjct: 530 A------LAEKAEKKEKEKAPPTQENYISIEDFKKVEIKVGLIKEAQRIEKSNKLLRLKV 583
Query: 651 DLGD-EVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALL 709
DLG+ +R +++G+ Y+PE L+ + V VVANL+P KL G S+GM+LA D + +AL+
Sbjct: 584 DLGENRLRQIISGIALDYEPESLVGQMVCVVANLKPAKLMGEMSEGMILAVRDNDNLALI 643
Query: 710 MPDKEVKLGAKV 721
P +E G+ +
Sbjct: 644 SPTREKIAGSLI 655
>sp|P56127|SYM_HELPY METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437663|pir||A64572 methionine--tRNA ligase (EC
6.1.1.10) - Helicobacter pylori (strain 26695)
>gi|2313521|gb|AAD07483.1| (AE000557) methionyl-tRNA
synthetase (metS) [Helicobacter pylori 26695]
Length = 650
Score = 236 bits (595), Expect = 8e-61
Identities = 199/730 (27%), Positives = 322/730 (43%), Gaps = 90/730 (12%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M + ++T+ + Y N H GH A L AD +Y L+GE+V F+ GTDEHG I A
Sbjct: 1 MQKSLITTPIYYVNDIPHIGH-AYTTLIADTLKKYYTLQGEEVFFLTGTDEHGQKIEQSA 59
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
+SP+ D K + + +D F RT H K Q F +E G + K
Sbjct: 60 RLRNQSPKAYADSISTIFKDQWDFFNLDYDGFIRTTDSEHQKCVQNAFEIMFEKGDIYKG 119
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
YC + YC +V C C R
Sbjct: 120 AYSGYYC------------VSCESYCAISKADNTNDKVL-------------CPDCLRET 154
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEGLEERAITR-DLNWG 236
+ + Y+ ++ + + L + K P KN V S+IE+GL + +ITR WG
Sbjct: 155 TLLEEESYFFRLSAYEKPLLDFYAKNPEAILPVYRKNEVTSFIEQGLLDLSITRTSFEWG 214
Query: 237 IPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIG 296
IP+P D K V+YVW +A + Y S +G N+ + + H +G
Sbjct: 215 IPLPKKMNDPK-HVVYVWLDALLNYAS-------ALGYLNDLDNKMAHFECAR---HIVG 263
Query: 297 KDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPY--DIPANEYLTLEGKKFSTSRNWAIW 354
KD + FHAI+WPAFLM+ NLP + + + T+EG K S S +
Sbjct: 264 KDILRFHAIYWPAFLMSL------------NLPLFKQLCVHGWWTIEGVKMSKSLGNVLD 311
Query: 355 VHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRY 414
+ + + LRY+L +P +D DFS RIN L N+LGN ++R L +Y
Sbjct: 312 AQKIAMEYGIEELRYFLLREVPFGQDGDFSKKALIERINANLNNDLGNLLNRLLGMAKKY 371
Query: 415 FDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQ 474
F+ + + ++ + LE++ + + + AL+ + ++ F N+ ++
Sbjct: 372 FNHSL-KSTKITAYYSKELEKVHQILDNANSFVPKMQLHKALEELFNVYDFLNKLIAKEE 430
Query: 475 PWKTAK-EDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP 533
PW K + + +++ + LL F+P ++ K+ + N + P
Sbjct: 431 PWVLHKNNESEKLEALLSLIANALLQSSFLLYAFMPKSAVKLANAFNTEIT--------P 482
Query: 534 AGHKVRKPEILFK-KVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGD 592
+ E FK K D I+ + L K K E EK G+
Sbjct: 483 DNY-----ERFFKAKKLQDMIL------------QDTEPLFSKMEKIEKT-----EKAGE 520
Query: 593 EAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDL 652
+ + KD K K + +E Y+ +DF K++++VG I E + ++KL +KVDL
Sbjct: 521 ASPEKNEKEKKDAKEKAPLK-QENYIGIEDFKKVEIKVGLIKEAQRIEKSNKLLRLKVDL 579
Query: 653 GD-EVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMP 711
G+ +R +++G+ Y+PE L+ + V VVANL+P KL G S+GM+LA D + +AL+ P
Sbjct: 580 GEGRLRQIISGIALDYEPESLVGQMVCVVANLKPAKLMGEMSEGMILAVRDSDNLALISP 639
Query: 712 DKEVKLGAKV 721
+E G+ +
Sbjct: 640 TREKIAGSLI 649
>emb|CAC10330.1| (AL442629) putative methionyl tRNA synthetase [Streptomyces
coelicolor]
Length = 538
Score = 218 bits (550), Expect = 2e-55
Identities = 159/573 (27%), Positives = 258/573 (44%), Gaps = 78/573 (13%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
Y V++ + Y N H GH A + D+ R+ R +GE V ++ GTDEHG I A
Sbjct: 14 YYVSTPIYYVNDAPHLGH-AYTTVAGDVLTRWHRQRGEKVWYLTGTDEHGQKIMRTAEAN 72
Query: 64 GRSPREIVDEF-HEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P+ D+ E K ++ I+ D F RT H QEF Y+ G + K
Sbjct: 73 GVTPQAWADKLVTESWKPLWEHLDIANDDFIRTTQKRHTDRVQEFVQDLYDKGEIYKGGY 132
Query: 123 KQAYCEHDKMF-LPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPIS 181
+ YC + + LP + G Y G + C I +P+
Sbjct: 133 EGPYCVGCEEYKLPGELLDGEGEYAGQK----------------------LCPIHKKPVE 170
Query: 182 FRDSAHYYIKMQDFAERLKRWIEKQPW---KPNVKNMVLSWIEEGLEERAITRD-LNWGI 237
+Y+ K+ +++E+L E P + +N V++++ +GL++ +I+R +WG+
Sbjct: 171 ILSEENYFFKLSEYSEKLLAHYEANPGFVQPESARNEVVNFVRQGLQDLSISRSTFDWGV 230
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
PVP D++ V+YVW +A + Y + +G +K+ +H +GK
Sbjct: 231 PVPWDDKH----VIYVWVDALLNYATA-------VGYNENPEKFESTFPAD---VHLVGK 276
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHE 357
D + FHAI WPA LMA G LP I AN +L + G+K S S I +
Sbjct: 277 DILRFHAIIWPAMLMAQGL----------PLPGKIAANGWLMVGGEKMSKSNLTGIKPQD 326
Query: 358 FLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDG 417
F D R+Y + +D FS+ DF R EL N+ GN R V +YF G
Sbjct: 327 LTTHFGVDAYRWYFLRAIAFGQDGSFSWEDFSARYTSELANDYGNLASRVAAMVGKYFGG 386
Query: 418 VVPER---GELDELDREAL-EEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHK 473
+P G+ ++ + L + + +A +++GE F+ + V N Y +
Sbjct: 387 ELPAATADGDAEQAIHDGLTKAVAEADRKIGE---ELDFQGGILAVFDFVKQVNGYITEQ 443
Query: 474 QPWKTAKED----KVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLL---------- 519
+PWK AK+D K R T + + + ++A+ +LL P +PD S+K+W L
Sbjct: 444 EPWKVAKDDSPEGKARLATILYTAAEALRAVAVLLNPIMPDTSQKLWDSLGAEPSLGALA 503
Query: 520 --NLDEVKRWEFRELPAGHKVRKPEILFKKVTD 550
++ + W LPAG V K +LF ++ +
Sbjct: 504 DQHVQDAADW--GRLPAGATVTKGAVLFPRLEE 534
>sp|O67298|SYM_AQUAE METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7519960|pir||G70408 methionine--tRNA ligase (EC
6.1.1.10) alpha - Aquifex aeolicus
>gi|2983692|gb|AAC07256.1| (AE000731) methionyl-tRNA
synthetase alpha subunit [Aquifex aeolicus]
Length = 497
Score = 215 bits (543), Expect = 1e-54
Identities = 160/554 (28%), Positives = 259/554 (45%), Gaps = 70/554 (12%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M ++ VT+ + Y N H GH A + AD RY RL+ DV F+ GTDEHG I +A
Sbjct: 4 MKKFYVTTPIYYVNDVPHLGH-AYTTIAADTIARYYRLRDYDVFFLTGTDEHGLKIQKKA 62
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
+ G SP+E+VD E+ K ++ KI + F RT P H K Q+ F + Y+ G +
Sbjct: 63 EELGISPKELVDRNAERFKKLWEFLKIEYTKFIRTTDPYHVKFVQKVFEECYKRGDIYLG 122
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
+ YC G E+ K + E+ + C I +
Sbjct: 123 EYEGWYC------------------VGCEEFKSE----------AELAEDHTCPIHQKKC 154
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQP--WKPNV-KNMVLSWIEEGLEERAITRD---LN 234
+ Y+ ++ + ++L EK P +P+ +N ++S++++GL++ ++TR +
Sbjct: 155 EYIKEPSYFFRLSKYQDKLLELYEKNPEFIQPDYRRNEIISFVKQGLKDLSVTRPRSRVK 214
Query: 235 WGIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHF 294
WGIPVP D E +YVWF+A YIS ++ + YW +H
Sbjct: 215 WGIPVPFDPE----HTIYVWFDALFNYIS---------ALEDKVEIYW------PADLHL 255
Query: 295 IGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIW 354
+GKD + FH ++WPAFLM+ G + LP + A+ + T+EGKK S + +
Sbjct: 256 VGKDILRFHTVYWPAFLMSLG----------YELPKKVFAHGWWTVEGKKMSKTLGNVVD 305
Query: 355 VHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRY 414
+E + + D +RY+L +P +D DFS RIN EL N +GN R + +++
Sbjct: 306 PYEVVQEYGLDEVRYFLLREVPFGQDGDFSKKAILNRINGELANEIGNLYSRVVNMAHKF 365
Query: 415 FDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQ 474
G V G DE + +E K ++ E + Y+ A++ ++ S+ N+Y D KQ
Sbjct: 366 LGGEV--SGARDEEYAKIAQESIKNYENYMEKVNFYK---AIEEILKFTSYLNKYVDEKQ 420
Query: 475 PWKTAKEDKVRTGTTVNISL-QIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELP 533
PW KE K V +L + L LL P P+ ++ +L E +
Sbjct: 421 PWALNKERKKEELQKVLYALVDGLFVLTHLLYPITPNKMKEALQMLGEKEFLKELKPYSK 480
Query: 534 AGHKVRKPEILFKK 547
+K+ + +ILF K
Sbjct: 481 NTYKLGERKILFPK 494
>sp|Q9ZCP0|SYM_RICPR METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7467887|pir||F71674 methionine--tRNA ligase (EC
6.1.1.10) (metS) RP683 - Rickettsia prowazekii
>gi|3861220|emb|CAA15120.1| (AJ235272) METHIONYL-TRNA
SYNTHETASE (metS) [Rickettsia prowazekii]
Length = 508
Score = 204 bits (514), Expect = 3e-51
Identities = 152/559 (27%), Positives = 264/559 (47%), Gaps = 72/559 (12%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
Y +T+ + Y N H GH A + +D+ R++R G+DV+F+ GTDEHG + A+ +
Sbjct: 5 YYITTPIYYVNDVAHIGH-AYTSVASDVIARFMRFCGKDVMFLTGTDEHGQKVEKAAINQ 63
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
P+ D+ + + IS D F RT H K F+ K +NG + + +
Sbjct: 64 NIDPQTFTDKTSQNFRDLMVAMNISNDDFIRTTENRHKKAVAVFWKKLLDNGAIYEGFYE 123
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y D+ F D+ E+ L P G P+ +
Sbjct: 124 GWYSVRDEAFY-------------------DESEINEDKLAP----------TGAPVEWV 154
Query: 184 DSAHYYIKMQDFAERLKRWIEKQP--WKP-NVKNMVLSWIEEGLEERAITR-DLNWGIPV 239
Y+ + + ++L + E P +P + +N V+S+I+ GL++ +I+R +WGI V
Sbjct: 155 KEPSYFFNLAKWQDKLLEFYELNPDFVRPISRRNEVISFIKSGLKDLSISRTTFHWGIKV 214
Query: 240 PLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNE---WKKYWLNIDGQTRVIHFIG 296
P + + V+YVW +A + YIS +G P++ + K+W + +G
Sbjct: 215 P----NNRKHVIYVWLDALVNYIS-------ALGYPDKQSNYAKFW------PANLQIVG 257
Query: 297 KDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVH 356
KD + FHA++WPAFLMA AE LP I + + T EG+K S S I
Sbjct: 258 KDILRFHAVYWPAFLMA----------AEIPLPKAIMVHGWWTNEGQKISKSLGNTIDPI 307
Query: 357 EFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFD 416
+D F D +RY+L + D++F+ ++ RIN EL N +GN +HR ++FV + D
Sbjct: 308 TLIDEFGVDQVRYFLMREVIFGADANFARNNLITRINSELSNKIGNLLHRIVSFVYKNND 367
Query: 417 GVVP--ERGELDELDREALEEIEKAFKEVGELIMN-YRFKDALKRVMSLASFGNRYFDHK 473
VP + G +D++ + + F + L+M+ L+ +++LA N Y ++
Sbjct: 368 AKVPLIKSGVIDKIYELPILKTAIKFAQENILLMDKTEINKILENIINLAEDANIYITNE 427
Query: 474 QPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRW-----E 528
PW D + + L++++ + I+L+PF+P+++ K+ L + + +R
Sbjct: 428 APWNLKTTDPDKMLEVLYSLLEVLRYIAIMLQPFVPNSANKMLDQLGVSKEERLFKHLVR 487
Query: 529 FRELPAGHKVRKPEILFKK 547
L AG + +P I+F K
Sbjct: 488 DHALKAGSNILEPSIIFPK 506
>pir||T47679 methionine--tRNA ligase (EC 6.1.1.10) - Arabidopsis thaliana
>gi|7076783|emb|CAB75898.1| (AL132975) methionyl-tRNA
synthetase (AtcpMetRS) [Arabidopsis thaliana]
Length = 616
Score = 200 bits (504), Expect = 4e-50
Identities = 143/527 (27%), Positives = 240/527 (45%), Gaps = 56/527 (10%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+++T+ L Y N P H G A + AD R+ RL G+ V+FI GTDEHG I+ A
Sbjct: 71 FVLTTPLYYVNAPPHMGS-AYTTIAADSIARFQRLLGKKVIFITGTDEHGEKIATSAAAN 129
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
GR+P E D + + ++ I++D F RT P H + +EF+ + + NG + + +
Sbjct: 130 GRNPPEHCDLISQSYRTLWKDLDIAYDKFIRTTDPKHEAIVKEFYARVFANGDIYRADYE 189
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
YC + + + +D+K E+L N C + P R
Sbjct: 190 GLYCVNCEEY---------------KDEK-------------ELLENNCCPVHQMPCVAR 221
Query: 184 DSAHYYIKMQDFAERLKRWIEKQP--WKPNVK-NMVLSWIEEGLEERAITRDL-NWGIPV 239
+Y+ + + + L+ + + P +P+ + N V SWI+ GL + +I+R L +WGIPV
Sbjct: 222 KEDNYFFALSKYQKPLEDILAQNPRFVQPSYRLNEVQSWIKSGLRDFSISRALVDWGIPV 281
Query: 240 PLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDN 299
P D++ + +YVWF+A +GYIS E K+ W +H IGKD
Sbjct: 282 PDDDK----QTIYVWFDALLGYISALTEDNKQQNLETAVSFGW------PASLHLIGKDI 331
Query: 300 IPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFL 359
+ FHA++WPA LM+ G LP + + +LT +G K S + E +
Sbjct: 332 LRFHAVYWPAMLMSAG----------LELPKMVFGHGFLTKDGMKMGKSLGNTLEPFELV 381
Query: 360 DVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVV 419
F D +RY+ + D D+S F +N L N +GN ++R L + + + +
Sbjct: 382 QKFGPDAVRYFFLREVEFGNDGDYSEDRFIKIVNAHLANTIGNLLNRTLGLLKKNCESTL 441
Query: 420 PERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTA 479
+ + +EK ++ N A + V+ + + GN Y D + PW
Sbjct: 442 VVDSTVAAEGVPLKDTVEKLVEKARTNYENLSLSSACEAVLEIGNAGNTYMDQRAPWFLF 501
Query: 480 KEDKV---RTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDE 523
K+ V + I L++++ + + L P P S +I+ L E
Sbjct: 502 KQGGVSAEEAAKDLVIILEVMRVIAVALSPVAPCLSLRIYSQLGYTE 548
>sp|Q55729|SYM_SYNY3 METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437666|pir||S76525 methionine--tRNA ligase (EC
6.1.1.10) - Synechocystis sp. (strain PCC 6803)
>gi|1001640|dbj|BAA10371.1| (D64002) methionyl-tRNA
synthetase [Synechocystis sp.]
Length = 532
Score = 200 bits (503), Expect = 5e-50
Identities = 147/533 (27%), Positives = 241/533 (44%), Gaps = 60/533 (11%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ VT+ L Y N H G A + AD R+ RL+G DV+ I GTDEHG I A +
Sbjct: 9 FSVTTPLYYVNDVPHLGS-AYTTVVADTLARFKRLQGYDVLMITGTDEHGQKIQRTAEAQ 67
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
P+ D + K ++ I +D F RT P H + ++FF + ++ G + +
Sbjct: 68 ELDPQTHCDRTVVKFKELWRSLNILYDRFSRTTDPRHLAIVKDFFQRVWDKGDIYLAQQQ 127
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y C C +K D E PL P R +R
Sbjct: 128 GWY----------------CVACEEFKEKRDLLEDNHCPLHP-----------NRKAEWR 160
Query: 184 DSAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEGLEERAITR-DLNWGIPV 239
D +Y+ ++ + L+ ++P + +N VL+++ +GL++ +I+R +L+WG P+
Sbjct: 161 DEENYFFRLSRYQHPLEELYAQRPEFIQPSSRRNEVLNFVAQGLQDFSISRVNLDWGFPL 220
Query: 240 PLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYW-LNIDGQTRVIHFIGKD 298
P D +YVWF+A +GY++ ++ + N K+W +N +H IGKD
Sbjct: 221 PND----PNHTIYVWFDALLGYVTALLDEDEEPNLTNALVKWWPIN-------LHLIGKD 269
Query: 299 NIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEF 358
+ FHA++WPA LM+ AE +P + + +LT +G+K S + +
Sbjct: 270 ILRFHAVYWPAMLMS----------AELAIPAQVFGHGFLTKDGQKMGKSLGNTVDPLDL 319
Query: 359 LDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGV 418
++ + D RYY + +D DF+ F +N +L N+LGN ++R L V +Y G
Sbjct: 320 INRYGEDAFRYYFLKEIEFGKDGDFNEQRFVNVLNADLANDLGNLLNRTLGMVKKYCQGQ 379
Query: 419 VPERGELDELDREALEEIEKAF-KEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWK 477
P+ D L+ + +EV F DA + + +L GN+Y D PWK
Sbjct: 380 GPQVMATDLAPDNPLKALGSHLGEEVSSAYERLSFTDACEAIFTLVRAGNKYIDDMAPWK 439
Query: 478 TAKEDKVRTGTTVNIS-LQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEF 529
K+ + V S L+ ++ LL P +P S KI+ L W+F
Sbjct: 440 LFKQGSQKEVEDVLYSVLESIRLSAYLLSPIVPRLSTKIYQQLGF----TWDF 488
>emb|CAB98261.1| (AL390096) methionyl-tRNA synthetase [Leishmania major]
Length = 747
Score = 193 bits (486), Expect = 5e-48
Identities = 150/561 (26%), Positives = 246/561 (43%), Gaps = 52/561 (9%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ T+ + Y N H GH+ + D+ RY R+KGE+V + GTDEHG ++ A K+
Sbjct: 211 FFATTPIYYVNASPHIGHVYSTLI-VDVLGRYHRVKGEEVFVMTGTDEHGQKVAEAAAKQ 269
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
G SP + + K FQ ++F RT P H KL Q+ + K G + +
Sbjct: 270 GVSPMDFTTSVSSEFKQCFQEMNYDMNYFIRTTNPTHEKLVQDIWKKLAAKGDIYLGKYE 329
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y D+ FL + V D+ G C+V G +++
Sbjct: 330 GWYSVSDESFLTAQNV------ADGVDRDGKPCKV--------------SLESGHVVTWV 369
Query: 184 DSAHYYIKMQDFAERLKRWIEKQP--WKPNVKNM-VLSWIEEGLEERAITRD----LNWG 236
+ +Y ++ F ERL ++ P P + V+ +E+GL + +I+R +NW
Sbjct: 370 EEENYMFRLSAFRERLLKYFHDHPNCIVPEFRRREVIKTVEKGLFDLSISRKRESVMNWS 429
Query: 237 IPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIG 296
IPVP DE +YVW +A Y + + G + + ++ +H +G
Sbjct: 430 IPVPGDER----HCIYVWLDALFNYYTGALTRVATDGTETLDEDHHA-LNRWPADVHVVG 484
Query: 297 KDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVH 356
KD + FHAI+WPAFLM+ AE LP + ++ + T + KK S S A
Sbjct: 485 KDILKFHAIYWPAFLMS----------AELPLPERLVSHGWWTKDHKKISKSLGNAFDPV 534
Query: 357 EFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFD 416
E F D L+Y+L D D+S + R+N EL + LGN V R + +
Sbjct: 535 EKAKEFGIDALKYFLMRESNFQDDGDYSDKNMVARLNGELADTLGNLVSRCVA-PKINVN 593
Query: 417 GVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPW 476
G+ PE E E D+ + + V + AL + + N Y PW
Sbjct: 594 GMWPEPAEYSESDKTLIASLNNLAGTVDHYYCLPDIQHALIAIFDVLRSLNAYVTENAPW 653
Query: 477 KTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKR-----WEFRE 531
K K D R GT + ++++ ++ + L+P +P +++I L + E R + F
Sbjct: 654 KLVKMDTARLGTVLYVTMEGLRICTMFLQPVMPQKAKEIMDALGVPEAARVGMENYLFGI 713
Query: 532 LPAGHKV---RKPEILFKKVT 549
+ G K+ + +++F+KVT
Sbjct: 714 VKPGTKIAGLAEGQVVFQKVT 734
>pir||T50641 methionine--tRNA ligase (EC 6.1.1.10) [imported] - Arabidopsis
thaliana >gi|2266985|emb|CAA74281.1| (Y13943) MEtRS
[Arabidopsis thaliana]
Length = 616
Score = 193 bits (485), Expect = 7e-48
Identities = 140/527 (26%), Positives = 239/527 (44%), Gaps = 56/527 (10%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+++T+ L Y N P H G A + AD R+ RL G+ V+FI GTDEHG I+ A
Sbjct: 71 FVLTTPLYYVNAPPHMGS-AYTTIAADSISRFQRLLGKKVIFITGTDEHGEKIATSAAAN 129
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
GR+P E D + + ++ I++D F RT P H + +EF+ + + NG + + +
Sbjct: 130 GRNPPEHCDLISQSYRTLWKDLDIAYDKFIRTTDPKHEAIVKEFYARVFANGDIYRADYE 189
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
YC + + + +D+K E+L N C + P R
Sbjct: 190 GLYCVNCEEY---------------KDEK-------------ELLENNCCPVHQMPCVAR 221
Query: 184 DSAHYYIKMQDFAERLKRWIEKQP--WKPNVK-NMVLSWIEEGLEERAITRDL-NWGIPV 239
+Y+ + + + L+ + + P +P+ + N V SWI+ GL + +I+R L + GIPV
Sbjct: 222 KEDNYFFALSKYQKPLEDILAQNPRFVQPSYRLNEVQSWIKSGLRDFSISRALVDXGIPV 281
Query: 240 PLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDN 299
P D++ + +YVWF+A +GYIS E K+ W +H IGKD
Sbjct: 282 PDDDK----QTIYVWFDALLGYISALTEDNKQQNLETAVSFGW------PASLHLIGKDI 331
Query: 300 IPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFL 359
+ FHA++WPA L++ G LP + + +LT +G K S + E +
Sbjct: 332 LRFHAVYWPAMLISAG----------LELPKMVFGHGFLTKDGMKMGKSLGNTLEPFELV 381
Query: 360 DVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVV 419
F D +RY+ + D D+S F +N L N +GN ++R L + + + +
Sbjct: 382 QKFGPDAVRYFFLREVEFGNDGDYSEDRFIKIVNAHLANTIGNLLNRTLGLLKKNCESTL 441
Query: 420 PERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTA 479
+ + +EK ++ N A + V+ + + GN Y D + PW
Sbjct: 442 VVDSTVAAEGVPLKDTVEKLVEKARTNYENLSLSSACEAVLEIGNAGNTYMDQRAPWFLF 501
Query: 480 KEDKV---RTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDE 523
K+ V + I L++++ + + L P P S +++ L E
Sbjct: 502 KQGGVSAEEAAKDLVIILEVMRVIAVALSPVAPCLSLRVYSQLGYSE 548
>pdb|1A8H| Methionyl-Trna Synthetase From Thermus Thermophilus
Length = 500
Score = 190 bits (477), Expect = 6e-47
Identities = 147/541 (27%), Positives = 233/541 (42%), Gaps = 79/541 (14%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKE 63
+ VT+ + Y N H GH A + AD R+ RL G F+ GTDEHG + A
Sbjct: 5 FYVTTPIYYVNAEPHLGH-AYTTVVADFLARWHRLDGYRTFFLTGTDEHGETVYRAAQAA 63
Query: 64 GRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTK 123
G P+ VD + K + I++D F RT H K+ Q K YE G +
Sbjct: 64 GEDPKAFVDRVSGRFKRAWDLLGIAYDDFIRTTEERHKKVVQLVLKKVYEAGDIY----- 118
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
Y E++ ++ C C R T + L+ C I GRP+ R
Sbjct: 119 --YGEYEGLY----------------------CVSCERFYTEKELVEGLCPIHGRPVERR 154
Query: 184 DSAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEGLEERAITRD---LNWGI 237
+Y+ +M+ + L+ +I++ P +N VL+ + E + + +I+R + WGI
Sbjct: 155 KEGNYFFRMEKYRPWLQEYIQENPDLIRPEGYRNEVLAMLAEPIGDLSISRPKSRVPWGI 214
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
P+P DE V YVWF+A + Y+S +++ + W W H IGK
Sbjct: 215 PLPWDE----NHVTYVWFDALLNYVS-ALDYPEGEAYRTFWPHAW----------HLIGK 259
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTL-------EGKKFSTSRN 350
D + HA+FWP L A G IP +L + +G+K S +
Sbjct: 260 DILKPHAVFWPTMLKAAG----------------IPMYRHLNVGGFLLGPDGRKMSKTLG 303
Query: 351 WAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTF 410
+ L+ + D LRYYL +P +D+ S + R +L ++LGN V R
Sbjct: 304 NVVDPFALLEKYGRDALRYYLLREIPYGQDTPVSEEALRTRYEADLADDLGNLVQRTRAM 363
Query: 411 VNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYF 470
+ R+ +G +PE + E L E + L+ +F AL+ M+ NRY
Sbjct: 364 LFRFAEGRIPE-----PVAGEELAEGTGLAGRLRPLVRELKFHVALEEAMAYVKALNRYI 418
Query: 471 DHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFR 530
+ K+PW+ K++ + ++ ++ ILL P +PD ++ L L E R E
Sbjct: 419 NEKKPWELFKKEPEEARAVLYRVVEGLRIASILLTPAMPDKMAELRRALGLKEEVRLEEA 478
Query: 531 E 531
E
Sbjct: 479 E 479
>sp|O05593|SYM_MYCTU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7478379|pir||B70603 probable methionyl-tra
synthetase - Mycobacterium tuberculosis (strain H37RV)
>gi|2052144|emb|CAB08142.1| (Z94752) metS [Mycobacterium
tuberculosis]
Length = 519
Score = 190 bits (477), Expect = 6e-47
Identities = 147/531 (27%), Positives = 236/531 (43%), Gaps = 65/531 (12%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M Y VT+A+ Y N H GH A Y+ D R+ RL DV F+ GTDEHG ++ A
Sbjct: 1 MKPYYVTTAIAYPNAAPHVGH-AYEYIATDAIARFKRLDRYDVRFLTGTDEHGLKVAQAA 59
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
G + + + + ISFD F RT H++ S+E + + G +
Sbjct: 60 AAAGVPTAALARRNSDVFQRMQEALNISFDRFIRTTDADHHEASKELWRRMSAAGDIYLD 119
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
Y D+ F + +E Q D G LT E G P+
Sbjct: 120 NYSGWYSVRDERFFVE-----------SETQLVD-----GTRLTVET---------GTPV 154
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEGLEERAITR-DLNWG 236
++ + Y+ ++ + ++L P +N V+S++ GL++ +I+R +WG
Sbjct: 155 TWTEEQTYFFRLSAYTDKLLAHYHANPDFIAPETRRNEVISFVSGGLDDLSISRTSFDWG 214
Query: 237 IPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNE----WKKYWLNIDGQTRVI 292
+ VP + V+YVW +A Y++ G P+ +++YW +
Sbjct: 215 VQVP----EHPDHVMYVWVDALTNYLT-------GAGFPDTDSELFRRYW------PADL 257
Query: 293 HFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWA 352
H IGKD I FHA++WPAFLM+ G LP I A+ +L G+K S S
Sbjct: 258 HMIGKDIIRFHAVYWPAFLMSAGI----------ELPRRIFAHGFLHNRGEKMSKSVGNI 307
Query: 353 IWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVN 412
+ + D +RY+L +P +D +S RIN +L N LGN R+L+ V
Sbjct: 308 VDPVALAEALGVDQVRYFLLREVPFGQDGSYSDEAIVTRINTDLANELGNLAQRSLSMVA 367
Query: 413 RYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDH 472
+ DG VP GE + D L + + V AL+ + + N+YF
Sbjct: 368 KNLDGRVPNPGEFADADAALLATADGLLERVRGHFDAQAMHLALEAIWLMLGDANKYFSV 427
Query: 473 KQPWKTAKE----DKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLL 519
+QPW K D+ R TT+ ++ ++V+ +L++P +P+++ KI LL
Sbjct: 428 QQPWVLRKSESEADQARFRTTLYVTCEVVRIAALLIQPVMPESAGKILDLL 478
>pir||C82922 methionyl-tRNA synthetase UU197 [imported] - Ureaplasma urealyticum
>gi|6899162|gb|AAF30604.1|AE002119_9 (AE002119)
methionyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 521
Score = 179 bits (450), Expect = 8e-44
Identities = 145/532 (27%), Positives = 238/532 (44%), Gaps = 61/532 (11%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
++ +++ + Y++G H GH A + AD+ RY RL G DV F+ G DEHG I +A +
Sbjct: 6 KFFISTPIYYSSGNPHIGH-AYTTIIADVLARYKRLFGYDVFFLTGMDEHGQKIQQKAFE 64
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
E SP+ +VD ++R ISF F RT H + Q+ F Y+ G +
Sbjct: 65 ENISPKALVDRNSIIFLNLWKRLNISFSKFIRTTQMDHEESVQKVFSYLYKQGKI----- 119
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAIC----GR 178
Y G G C C P +I + I G
Sbjct: 120 ----------------------YLG--QWTGYYCVSCEENYNPAEIIKSQDNIMLCRMGH 155
Query: 179 PISFRDSAHYYIKMQDFAERLKRWIEKQP--WKPNVK-NMVLSWIEEGLEERAITRD-LN 234
+ + Y+ KM D A LK + + P PN + N +++ LE+ +I+R +
Sbjct: 156 KLETKSEESYFYKMSDQAPFLKTYYQNHPNFIIPNERANEMVNNFLNNLEDLSISRTTFD 215
Query: 235 WGIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNE-WKKYWLNIDGQTRVIH 293
WGIP+ + + V+YVW +A + Y++ T + E ++KYW D +T ++H
Sbjct: 216 WGIPIAENPKH----VIYVWLDALMNYLTAT----GYLSNNEELFQKYWC--DNETEIVH 265
Query: 294 FIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAI 353
+ K+ FH I+WP FL + + P I ++ ++ + K S S I
Sbjct: 266 LLSKEIARFHCIYWPIFLN----------DLQIRFPSTILSHGWIITKEGKMSKSLGNVI 315
Query: 354 WVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNR 413
+ +D + D LRYYL + RD+ FS + N +L N+ GN + R L + +
Sbjct: 316 DPNVLIDTYGVDALRYYLMADLSLFRDAIFSEDNLIETYNTQLANSYGNMISRTLGMLKK 375
Query: 414 YFDGVVPERGELDELDREALEE-IEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDH 472
Y + +VP+ + E LE I K + V E I Y AL + + N+Y +
Sbjct: 376 YRNNIVPKYVGCVLKNDEKLENLINKNIELVQENINKYSIDKALNCIQEILVEANKYIED 435
Query: 473 KQPWKTAKEDKVRTGTTVNISL-QIVKALGILLEPFLPDASEKIWHLLNLDE 523
+PW+ AK + + ++ + L ++++ LL P L + S+K LN DE
Sbjct: 436 NKPWELAKNQQEQELDSLLVHLVKVIQVTTTLLSPILIEGSKKAVEQLNFDE 487
>sp|P47267|SYM_MYCGE METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|1361720|pir||C64202 methionine--tRNA ligase (EC
6.1.1.10) - Mycoplasma genitalium
>gi|3844630|gb|AAC71237.1| (U39681) methionyl-tRNA
synthetase (metS) [Mycoplasma genitalium]
Length = 512
Score = 166 bits (415), Expect = 1e-39
Identities = 143/562 (25%), Positives = 240/562 (42%), Gaps = 65/562 (11%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M R +T+ + YA+G H GH L AD+ R+ G + + G+DEHG I +A
Sbjct: 1 MKRCYITTPIYYASGKPHIGHAFTTIL-ADVIKRFKIQNGYEAFLLVGSDEHGNKIESKA 59
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
P+ VD + K+ ++ ISFD F RT IH + Q+ F Y+ + +
Sbjct: 60 KSLNLDPKTFVDINAQAFKLMWKTLNISFDHFIRTTDEIHKQQVQKTFQDLYDKKLIYQS 119
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAIC--GR 178
K AYC +CE N + +C G
Sbjct: 120 EWKGAYCV--------------------------ECE------QNYFTFNKQTMLCEIGH 147
Query: 179 PISFRDSAHYYIKMQDFAERLKRWIEKQPW----KPNVKNMVLSWIEEGLEERAITR-DL 233
+S ++I ++ I K K + ++I GL + A+TR ++
Sbjct: 148 NLSLVQEPCWFISFSSTKNWIETTIGKNQLNIIPKSRASELKNNFINNGLNDLALTRKNV 207
Query: 234 NWGIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIH 293
WGI VP D + +YVWF+A YI+ R G PN + K+W N + + VIH
Sbjct: 208 TWGIKVPFDPN----QTIYVWFDALFSYIT---NLGFRNGDPN-FIKWWNNDNKEREVIH 259
Query: 294 FIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTL-EGKKFSTSRNWA 352
I ++ FH I+WP FL + LP ++ ++ EG+K S S N
Sbjct: 260 LISREITRFHCIYWPIFLHLL----------DIKLPTQFLSHGWIVDGEGRKMSKSLNNV 309
Query: 353 IWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVN 412
I + +D F D RY L M +D+ S S K N +L N+ GN V R +
Sbjct: 310 ISPEQLIDQFGVDGTRYCLLKEMRLDKDNRCSVSILKEIYNADLANSFGNHVSRTFGMIK 369
Query: 413 RYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDH 472
+Y +G + + D ++ + I+++ + +Y F A+ ++ + ++ D
Sbjct: 370 KYLNGKLEYQIITDNALQKIMILIDESIVQFDHYFNSYEFYRAINLLLKIVFELSKLIDD 429
Query: 473 KQPWKTAKEDKVRTGTTVNIS-LQIVKALGILLEPFLPDASEKIWHLLNL--DEVKRWEF 529
+PW+ K + + + ++ V+ +LL P L + + K++HL N D ++ +
Sbjct: 430 FKPWELFKNQEFSLLKQLLFTCVRCVQVCYVLLTPILVNTASKVFHLFNFADDACRKDQL 489
Query: 530 RELPAGHKV---RKPEILFKKV 548
R+ K+ E+LFK+V
Sbjct: 490 RDATLLKKIIISNSMEVLFKRV 511
>sp|P75091|SYM_MYCPN METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|2146334|pir||S73457 methionine--tRNA ligase (EC
6.1.1.10) metS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1673790|gb|AAB95779.1| (AE000015)
methionyl-tRNA synthetase [Mycoplasma pneumoniae]
Length = 512
Score = 163 bits (408), Expect = 7e-39
Identities = 140/531 (26%), Positives = 233/531 (43%), Gaps = 52/531 (9%)
Query: 1 MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRA 60
M R +T+ + YA+G H GH L AD+ RY + G + F+ GTDEHG I +A
Sbjct: 1 MKRCYITTPIYYASGKPHIGHAFTTIL-ADVIKRYKQQNGYEAYFLTGTDEHGNKIESKA 59
Query: 61 LKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKK 120
G P+ VD+ + +++ I+FD F RT H Q F Y+ G + +
Sbjct: 60 KSLGLDPQTFVDQNVAYFQQMWKQLDINFDHFIRTTDLSHKAQVQHAFQLLYDKGLIYQS 119
Query: 121 VTKQAYC-EHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRP 179
+ AYC E ++ + D++ CE+ G LT ++ P
Sbjct: 120 NWEGAYCVECEQNYF-------------TYDKQTMLCEI-GHQLT--LVQEPSLF----- 158
Query: 180 ISFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITR-DLNWGIP 238
I+F+DS + + + K I + +KN ++++ GL + A+TR ++ WGIP
Sbjct: 159 IAFKDSKDW---IGEMIATNKLNITPESRAAELKN---NFLDGGLNDLALTRQNVTWGIP 212
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYI-SITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGK 297
VP D + + +YVWF+A YI ++ H ++ K+W N D + VIH I +
Sbjct: 213 VPFDNK----QTIYVWFDALFNYITNLGFAH-----NDPKFNKWWNNNDEEHEVIHLISR 263
Query: 298 DNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLT-LEGKKFSTSRNWAIWVH 356
+ FH I+WP FL G + LP ++ ++ G K S S I
Sbjct: 264 EITRFHCIYWPIFLHQLG----------FKLPTQFLSHGWIVDGNGHKMSKSLGNVISPE 313
Query: 357 EFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFD 416
E L F D RY L M +D+ S + FK N +L N+ GN R + +Y
Sbjct: 314 ELLAQFGVDGTRYCLLKEMRLDKDNRCSMAIFKDIYNADLANSFGNHASRTFGMIKKYLG 373
Query: 417 GVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPW 476
G + D ++ +++ +A + N++F + ++ L ++ D +PW
Sbjct: 374 GQLDFIEVQDPQVKQLMDQANQAMVQFDTAWNNFQFYKGINGLLQLVFQASKLIDQLKPW 433
Query: 477 KTAKE-DKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKR 526
+ K+ D + ++ + +LL P L S +I+ L N R
Sbjct: 434 ELVKQTDYTLLKQLLFACVRCTQVCFVLLAPILVHTSTQIFDLFNFSAQAR 484
>sp|Q9ZHD7|SYM_BUCAP METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|4038324|gb|AAC97364.1| (AF067228) methionyl-tRNA
synthetase [Buchnera aphidicola]
Length = 234
Score = 161 bits (404), Expect = 2e-38
Identities = 84/229 (36%), Positives = 125/229 (53%), Gaps = 1/229 (0%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+ +VT ALPYANGPIH GH+ ++ ADI+VRY R++ +V FI D HGT I ++ K
Sbjct: 7 KILVTCALPYANGPIHIGHML-EHIQADIWVRYQRMRNNEVWFISSDDAHGTAIMLKSEK 65
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G +P +++ + E+ I F IS D + T + L ++ FL E + +K
Sbjct: 66 LGITPIKLIKKIKEEHIIDFSNFNISHDNYHSTHCVENLFLLRKIFLSLSEQKLINEKKI 125
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Q Y KMFLPDRF+ GTCP+C +++Q GD CE+CG P L+NP I
Sbjct: 126 FQFYDNTKKMFLPDRFIKGTCPFCSSKNQNGDNCEICGSIYEPTDLVNPISVISNSVPIL 185
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITR 231
+++ H Y + F L +WI + +V W++ GL+E I+R
Sbjct: 186 KNTTHLYFNLPLFTNMLNKWIHSGILEKSVAKKTEEWLKSGLKEWGISR 234
>emb|CAB81970.1| (AL132880) predicted using Genefinder; preliminary prediction
[Caenorhabditis elegans]
Length = 622
Score = 152 bits (379), Expect = 2e-35
Identities = 121/437 (27%), Positives = 203/437 (45%), Gaps = 62/437 (14%)
Query: 18 HAGHLAGAYLPADIFVRYLRLK--GEDVVFICGTDEHGTPISFRALKEGRSPREIVDEFH 75
H GH A L D+ R+ RLK G F GTDEHG+ I AL +P++ D
Sbjct: 200 HIGHAYTAVL-CDVAHRWNRLKHPGAQAQFSIGTDEHGSKIFQAALAAKSTPKQFCDRVS 258
Query: 76 EQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQAYCEHDKMFLP 135
+ F ++S F RT P H + Q F++K +NG++ K Y D+ F+P
Sbjct: 259 SKFSDLFTDLELSHTNFIRTTDPAHLEAVQHFWMKIQDNGYIYKSTYSGYYSITDECFIP 318
Query: 136 DRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRDSAHYYIKMQDF 195
+ V+ GAE ++ + G P+ + + +Y ++ +F
Sbjct: 319 EEDVVKKIVEGGAE----------------KLTLKSN----GTPVEWIEEENYMFRLSEF 358
Query: 196 AERLKRWIEKQ---PWKPNVKNMVLSWIEEGLEERAITRD---LNWGIPVPLDEEDMKGK 249
E++ WI ++ K++ L+ +E E+ +I+R L+WGIPVP D +
Sbjct: 359 REKVAEWINRENIVVHPSKYKSLALTSLEMS-EDLSISRSRSRLSWGIPVPNDPT----Q 413
Query: 250 VLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPFHAIFWPA 309
+YVW +A + Y+++T G PN + W IGKD FH +WPA
Sbjct: 414 TIYVWLDALVNYLTVT-------GFPNA-QSVW------PPTCQVIGKDITKFHLYYWPA 459
Query: 310 FLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDVFPADYLRY 369
FLMA G +LP + + + ++ K S S + E + F A+ LRY
Sbjct: 460 FLMAAG----------LSLPQKVFIHGHWLIDNVKMSKSLGNVVNPSEAITKFTAEGLRY 509
Query: 370 YLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRA-LTFVNRYFDGVVPERGELDEL 428
+L + D F+++ IN +LVNN+GN ++R+ + +N+ +G+ P+ E++++
Sbjct: 510 FLLKHGNPSYDCSFNWNSCLQTINSDLVNNVGNLLNRSTVEKINK--EGMYPKM-EIEDI 566
Query: 429 DREALEEIEKAFKEVGE 445
+ E E +K + V E
Sbjct: 567 EAEIRENAKKLMEMVEE 583
>pir||T35923 probable tRNA synthetase - Streptomyces coelicolor
>gi|4158182|emb|CAA22745.1| (AL035206) putative tRNA
synthetase [Streptomyces coelicolor A3(2)]
Length = 506
Score = 150 bits (376), Expect = 4e-35
Identities = 109/393 (27%), Positives = 176/393 (44%), Gaps = 25/393 (6%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
R++VT+ P NG +H GHL+G YL AD+F R R+ G V++ G D+H T + A +
Sbjct: 7 RFLVTATPPTTNGDVHVGHLSGPYLGADVFSRAQRMLGHTVLYASGGDDHQTYVVTTAER 66
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G P E+ + +I T + A I D F + ++ +EFF + G L +
Sbjct: 67 LGLDPVELAARCNREIVGTLELAGIDIDAFTSPDDAYRAEV-REFFTGLHRAGRLKTRTW 125
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
YC +L + F G CP C G CE CG P + L+ P G +
Sbjct: 126 TFPYCGRTGRYLLEAFATGYCPEC-LVGTCGAICENCGHPNDVDSLLFPASTGAGPAATT 184
Query: 183 --RDSAHYYIKMQDFAERLKRW--IEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIP 238
R++ + ++++ E+ + + +P+V V + L + ++ +WGIP
Sbjct: 185 QPRETEILVLPLEEYREQFTEFYRARRATMRPHVLRFVDEMLSRPLPDFPVSYPADWGIP 244
Query: 239 VPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIG---KPNEWKKYWLNIDGQTRVIHFI 295
V +D D G+V VW E G + R G P W D ++ F+
Sbjct: 245 VGIDGFD--GQVFNVWAEMLPGLRHMAEAARARRGPATPPGVWA-----ADSGFELVQFL 297
Query: 296 GKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWV 355
G DN + A A+G + P I NE+ L+G KFSTSR +W
Sbjct: 298 GYDNTFYFAFAHLGLTFAHGGLTE---------PAAIVTNEFYHLDGAKFSTSRRHLVWA 348
Query: 356 HEFLDVFPADYLRYYLTTIMPETRDSDFSFSDF 388
+ + + AD +R++L PE + ++F+ +DF
Sbjct: 349 RDLVGKYGADNVRFHLALDNPEHQPANFTEADF 381
>pir||T38454 methionyl-trna synthetase, mitochondrial - fission yeast
(Schizosaccharomyces pombe) >gi|2388946|emb|CAB11680.1|
(Z98978) methionyl-trna synthetase, mitochondrial
[Schizosaccharomyces pombe]
Length = 539
Score = 149 bits (372), Expect = 1e-34
Identities = 137/539 (25%), Positives = 231/539 (42%), Gaps = 66/539 (12%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGE-DVVFICGTDEHGTPISFRALK 62
Y +T+ + Y N H GHL L D R+ LK + V+ GTDEHG + A
Sbjct: 21 YFLTTPIFYVNAAPHLGHLYSLVL-TDAIARFQNLKPDVSVISSTGTDEHGLKVQTVAQT 79
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
EG SP ++ D ++ A F F RT P H QEF+ + G + +
Sbjct: 80 EGVSPLQLCDRNSKRFADLAVAANTKFTHFIRTTNPKHQASVQEFWKTIQKAGMISFERH 139
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAI-CGRPIS 181
+ YC D+ F P+ + + + P R ++ G+ +
Sbjct: 140 EGWYCVSDETFYPESAI--------------------QKVVDPATKQEKRVSMETGKEVQ 179
Query: 182 FRDSAHYYIKMQDFAERLKRWIEKQP--WKPNV-KNMVLSWIEEGLEERAITRD---LNW 235
+ +Y+ + F RL K P +P++ VL ++ G+ + +I+R L+W
Sbjct: 180 WSSEMNYHFLLSKFQSRLIEHYNKNPNFVQPSIFHTQVLEELKTGISDLSISRPKQRLSW 239
Query: 236 GIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNID-----GQTR 290
GIPVP + + + +YVW +A I YIS+ IG P WLN G
Sbjct: 240 GIPVPGNSQ----QTIYVWLDALINYISV-------IGYP------WLNEKSSLSAGWPA 282
Query: 291 VIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRN 350
+H IGKD I FH I+WPAFLMA G LP I + + T+ K S S
Sbjct: 283 NMHVIGKDIIRFHCIYWPAFLMAAG----------LPLPEKILVHSHWTMNKVKMSKSLG 332
Query: 351 WAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALT- 409
+ ++ + D +RYYL T DS+F + + +L +LG + R +
Sbjct: 333 NVVDPFWLIEKYGVDTIRYYLLKRGRLTSDSNFDIEELEKDEEHDLRRSLGVLLSRLQSK 392
Query: 410 --FVNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGN 467
F++ ++ + E + + + E+ + + I + + V S+
Sbjct: 393 KLFISNEIQKQWHKKDDFTEYE-DIVHELIELPVVCAQSIDGGCVYEVINLVQSVLRRVT 451
Query: 468 RYFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKR 526
+ F K+PWK + + + + T + ++ ++ GILL+P +P S ++ L + + +R
Sbjct: 452 KLFQLKEPWKLSDDSQEKIDTLMLVA-HSLRISGILLQPIMPTKSTELLDQLGIPKNQR 509
>emb|CAA32778.1| (X14629) methionyl-tRNA synthase (AA 1 - 575) [Saccharomyces
cerevisiae]
Length = 575
Score = 127 bits (317), Expect = 3e-28
Identities = 127/558 (22%), Positives = 225/558 (39%), Gaps = 78/558 (13%)
Query: 6 VTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG- 64
VT+ + Y N H GHL + L +D++ R+ KG F GTDEHG I + G
Sbjct: 17 VTTPIFYPNAKPHLGHLYSSLL-SDVYHRWQLFKGNLSFFTTGTDEHGLKIQCASESNGF 75
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
P++ VD+ + + + I++ F RT P H + + + +NG++ K
Sbjct: 76 DQPKKFVDKLYPEFVQLDKIYGINYTRFIRTTDPDHIENVMKLWELCLKNGYIYMGEHKG 135
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
Y D+ F P+ VI +D K D G+ L E + ++
Sbjct: 136 WYSISDETFYPESKVI--------KDPKND-----GKYLNTE---------SKNEVVYQS 173
Query: 185 SAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEG--LEERAITRD---LNWG 236
+Y+ ++ F +++ I K P + + ++ +L +E G L + +I+R L WG
Sbjct: 174 ETNYFFRLSLFNKKIVDHIRKNPDFIFPASKRDQILKELETGGTLPDLSISRPSARLKWG 233
Query: 237 IPVPLDEEDMKGKVLYVWFEAPIGYIS--------------ITIEHFKRIGKPNEWKKYW 282
IP P D +YVWF+A Y+S + H+
Sbjct: 234 IPTPNDPSQK----VYVWFDALCNYLSSIGGIPSILSNATEVVSRHYSDKSNVKGQLLIP 289
Query: 283 LNIDGQTRVIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEG 342
+ Q IH IGKD FH ++WP+FL+A G LP I + + G
Sbjct: 290 YPKEVQRNTIHVIGKDIAKFHTVYWPSFLLAAG----------LPLPRQIVVHGHWLCNG 339
Query: 343 KKFSTSRNWAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGN 402
K S S + + + AD +R++L D DF + E LV+ GN
Sbjct: 340 MKMSKSLGNVVDPIDMARYYGADIVRWFLLENSKLEEDGDFQEAKL-YETRELLVSKWGN 398
Query: 403 FVHR-----------ALTF---VNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIM 448
++R + F N F + + E + + K+ + E I
Sbjct: 399 LINRCCGSKFNIERAVMKFSDKANFQFQEIFQNEPIVSERIENLAKLLNKSQEVFDEKIA 458
Query: 449 NYRFKDALKRVMSLASFGNRYFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFL 508
+++ L+ V S+ + N + +PW+ + + + ++++ + L IL + +
Sbjct: 459 IFQYPQLLRHVWSIINDANTLVQNSKPWERELDQQ---DNIIFLAMETSRILSILCQSII 515
Query: 509 PDASEKIWHLLNLDEVKR 526
P S+ +++ + KR
Sbjct: 516 PSLSQSFLDRIDVSKEKR 533
>gi|6321610 mitochondrial methionyl-tRNA synthetase; Msm1p [Saccharomyces
cerevisiae] >gi|1711640|sp|P22438|SYMM_YEAST
METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL
(METHIONINE--TRNA LIGASE) (METRS)
>gi|2144554|pir||SYBYMM methionine--tRNA ligase (EC
6.1.1.10), mitochondrial - yeast (Saccharomyces
cerevisiae) >gi|1323302|emb|CAA97197.1| (Z72956) ORF
YGR171c [Saccharomyces cerevisiae]
Length = 575
Score = 127 bits (317), Expect = 3e-28
Identities = 127/558 (22%), Positives = 225/558 (39%), Gaps = 78/558 (13%)
Query: 6 VTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEG- 64
VT+ + Y N H GHL + L +D++ R+ KG F GTDEHG I + G
Sbjct: 17 VTTPIFYPNAKPHLGHLYSSLL-SDVYHRWQLFKGNLSFFTTGTDEHGLKIQCASESNGF 75
Query: 65 RSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQ 124
P++ VD+ + + + I++ F RT P H + + + +NG++ K
Sbjct: 76 DQPKKFVDKLYPEFVQLDKIYGINYTRFIRTTDPDHIENVMKLWELCLKNGYIYMGEHKG 135
Query: 125 AYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRD 184
Y D+ F P+ VI +D K D G+ L E + ++
Sbjct: 136 WYSISDETFYPESKVI--------KDPKND-----GKYLNTE---------SKNEVVYQS 173
Query: 185 SAHYYIKMQDFAERLKRWIEKQP---WKPNVKNMVLSWIEEG--LEERAITRD---LNWG 236
+Y+ ++ F +++ I K P + + ++ +L +E G L + +I+R L WG
Sbjct: 174 ETNYFFRLSLFNKKIVDHIRKNPDFIFPASKRDQILKELETGGTLPDLSISRPSARLKWG 233
Query: 237 IPVPLDEEDMKGKVLYVWFEAPIGYIS--------------ITIEHFKRIGKPNEWKKYW 282
IP P D +YVWF+A Y+S + H+
Sbjct: 234 IPTPNDPSQK----VYVWFDALCNYLSSIGGIPSILSNATEVVSRHYSDKSNVKGQLLIP 289
Query: 283 LNIDGQTRVIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEG 342
+ Q IH IGKD FH ++WP+FL+A G LP I + + G
Sbjct: 290 YPKEVQRNTIHVIGKDIAKFHTVYWPSFLLAAG----------LPLPRQIVVHGHWLCNG 339
Query: 343 KKFSTSRNWAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGN 402
K S S + + + AD +R++L D DF + E LV+ GN
Sbjct: 340 MKMSKSLGNVVDPIDMARYYGADIVRWFLLENSKLEEDGDFQEAKL-YETRELLVSKWGN 398
Query: 403 FVHR-----------ALTF---VNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIM 448
++R + F N F + + E + + K+ + E I
Sbjct: 399 LINRCCGSKFNIERAVMKFSDKANFQFQEIFQNEPIVSERIENLAKLLNKSQEVFDEKIA 458
Query: 449 NYRFKDALKRVMSLASFGNRYFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFL 508
+++ L+ V S+ + N + +PW+ + + + ++++ + L IL + +
Sbjct: 459 IFQYPQLLRHVWSIINDANTLVQNSKPWERELDQQ---DNIIFLAMETSRILSILCQSII 515
Query: 509 PDASEKIWHLLNLDEVKR 526
P S+ +++ + KR
Sbjct: 516 PSLSQSFLDRIDVSKEKR 533
>gb|AAF55037.1| (AE003703) CG8684 gene product [Drosophila melanogaster]
Length = 356
Score = 121 bits (301), Expect = 2e-26
Identities = 99/376 (26%), Positives = 163/376 (43%), Gaps = 59/376 (15%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLK--GEDVVFICGTDEHGTPISFRAL 61
+ VT+ + Y N H GHL A + AD RY RL+ +DV GTDEHGT I A
Sbjct: 20 HYVTTPIFYVNAAPHIGHLYSAVI-ADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAAS 78
Query: 62 KEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKV 121
G + D+ ++ + F+ A I D F RT H + F+ + GH+
Sbjct: 79 LHGVPVAKYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAA 138
Query: 122 TKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPIS 181
YC D+ FL D + D E G + E G P+
Sbjct: 139 YSGWYCVSDETFLTD------------SQLRLD--EATGTRYSLE---------SGHPVE 175
Query: 182 FRDSAHYYIKMQDFAERLKRWI--EKQPWKPNVKNMVLSWIEEGLEERAITRDLN---WG 236
+ + +Y ++ F + ++ W+ E + + ++L + E L + +++R N W
Sbjct: 176 WTEETNYMFRLSQFQDDVRHWVKTEARVRPAKFEKILLDTLSEPLPDVSVSRPSNRVHWA 235
Query: 237 IPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNE-WKKYWLNIDGQTRVIHFI 295
IPVP D+ + +YVW +A + Y+S +G P+E + +W I
Sbjct: 236 IPVPDDDS----QTVYVWLDALVNYLS-------SVGYPDEKFSAHWPPAQ------QVI 278
Query: 296 GKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWV 355
GKD + FH I+W AFL+A G P + + + T++G+K S S++ +
Sbjct: 279 GKDILKFHGIYWTAFLLAAG----------LEPPGQLYVHSHWTVDGQKMSKSKHNVVDP 328
Query: 356 HEFLDVFPADYLRYYL 371
+ + + LRY+L
Sbjct: 329 LQAAQQYTMEGLRYFL 344
>sp|O74634|SYMM_CANAL METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL (METHIONINE--TRNA LIGASE)
(METRS) >gi|3641642|dbj|BAA33373.1| (AB006140)
mitochondrial methionyl-tRNA synthetase [Candida
albicans]
Length = 577
Score = 115 bits (286), Expect = 1e-24
Identities = 127/563 (22%), Positives = 240/563 (42%), Gaps = 88/563 (15%)
Query: 4 YMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLK-GEDVVFICGTDEHGTPISFRALK 62
+ +T+ + Y N H GHL + L AD ++ +L ++ + GTDEHG I A K
Sbjct: 20 FYITTPIFYVNAAPHIGHLY-SMLIADTRNKWEKLNPSKESFMLTGTDEHGLKIQSTAEK 78
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVT 122
G P+ +VD+ + ++ +++D F RT H +L + F+ E G +
Sbjct: 79 LGLEPKVLVDKVSQNFSKLAEQFDVNYDRFIRTTDNDHIELVRYFWNLMMEKGFIYTDTH 138
Query: 123 KQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISF 182
Y D+ F P+ + E K + E++ +
Sbjct: 139 SGWYSISDETFFPETQI--------EEVVKNGKAVKISSETKNEVV-------------Y 177
Query: 183 RDSAHYYIKMQDFAERLKRWIEKQPW--KPNVK-NMVLSWIEEG-LEERAITRD---LNW 235
++ +Y+ K+ F E+L +++++ P KP + +L +E+ L + +I+R L W
Sbjct: 178 QEETNYFFKLSMFQEQLIQFLKQNPEFIKPKHRYQFILKELEDTKLPDLSISRPSSRLKW 237
Query: 236 GIPVPLDEEDMKGKVLYVWFEAPIGYISIT-IEHFKRIGKPNEWKKYWLNIDGQTRVIHF 294
I VP D +YVWF+A + Y++ T H G + K+ + H
Sbjct: 238 SIEVPNDSTQK----IYVWFDALLNYLTATKFPH----GFEVQDSKFVTPENSIWPATHV 289
Query: 295 IGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIW 354
IGKD I FH I+WP FLMA G LP + + + +G K S S +
Sbjct: 290 IGKDIIRFHCIYWPIFLMAAG----------IELPKQVIVHSHWLCDGFKMSKSLGNLVD 339
Query: 355 VHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEE--------LVNNLG--NF- 403
E + + D +R++L + D D FS+ ++ + + L++ +G NF
Sbjct: 340 PMEISEYYGVDPVRFFL--VENSNIDDDCKFSEELLQRSRDAVLGKYCNLISRIGGKNFS 397
Query: 404 VHRAL-TFVNRYFDGVVPERGELDELDREALE-----------EIEKAFKEVGELIMNYR 451
+ A+ +F + F+ + E E ++++++E ++ + ++ N+
Sbjct: 398 IEEAVKSFASGEFNN-IREIIETYTINKDSVEGLLSSLNKLTTDLNDLYNQMDHYFTNFD 456
Query: 452 FKDALKRVMSLASFGNRYFDHKQPWKTAK-------------EDKVRTGTTVNISLQIVK 498
+ A++ S+ + N+ F +PW K + ++ V + + +
Sbjct: 457 YIRAIQCWWSVINQANQIFQSAEPWTYVKLINSPETPAELKEKYRILNNYFVYLCAETTR 516
Query: 499 ALGILLEPFLPDASEKIWHLLNL 521
IL++P +P S+KI LN+
Sbjct: 517 ISSILIQPVMPQLSKKILDRLNV 539
>pir||F70338 methionine--tRNA ligase (EC 6.1.1.10) beta - Aquifex aeolicus
>gi|2983087|gb|AAC06693.1| (AE000689) methionyl-tRNA
synthetase beta subunit [Aquifex aeolicus]
Length = 111
Score = 115 bits (285), Expect = 2e-24
Identities = 52/104 (50%), Positives = 80/104 (76%)
Query: 618 VKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYV 677
+ +DF K+DLRV K++ + ++KL + + LGDE RT+VAG+ KYY PEEL+ + +
Sbjct: 7 IGIEDFLKVDLRVAKVLSAERVEGSEKLLKLTLSLGDEERTVVAGIAKYYTPEELVGKKI 66
Query: 678 VVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAKV 721
V+VANL+P+K+ GI SQGM+LAA DGE +++++PD++VK GAK+
Sbjct: 67 VIVANLKPRKIFGIESQGMILAASDGENLSVIVPDRDVKEGAKL 110
>sp|P42589|YGJH_ECOLI HYPOTHETICAL 12.3 KD PROTEIN IN ILEX-EBGR INTERGENIC REGION
>gi|7451808|pir||G65095 hypothetical 12.3 kD protein in
ileX-ebgR intergenic region - Escherichia coli (strain
K-12) >gi|606012|gb|AAA57875.1| (U18997) ORF_f110
[Escherichia coli] >gi|1789455|gb|AAC76109.1| (AE000389)
putative tRNA synthetase [Escherichia coli K12]
Length = 110
Score = 101 bits (250), Expect = 2e-20
Identities = 52/106 (49%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
Query: 618 VKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYV 677
V + DFA+L++RVGKI+EVK H NADKLY+V+VD+G + V L YY EEL+ + V
Sbjct: 4 VAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGQKTLQTVTSLVPYYSEEELMGKTV 63
Query: 678 VVVANLEPKKLRGIGSQGMLLAA--DDGERVALLMPDKEVKLGAKV 721
VV+ NL+ K+RG S+ MLL A DDG LL P++ + G +V
Sbjct: 64 VVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERMMPAGVRV 109
>pir||H72655 protein secretion chaperonin APE0675 [similarity] - Aeropyrum
pernix (strain K1) >gi|5104333|dbj|BAA79648.1|
(AP000060) 117aa long hypothetical methionyl-tRNA
synthetase [Aeropyrum pernix]
Length = 117
Score = 98.7 bits (242), Expect = 2e-19
Identities = 50/111 (45%), Positives = 78/111 (70%), Gaps = 2/111 (1%)
Query: 613 GKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEEL 672
G+ + +DFAK+DLRVG++++ + P++ KL + VD+G E R ++AG+ K+Y PEEL
Sbjct: 6 GEAGLIGIEDFAKVDLRVGRVVKAERLPHSKKLLKLIVDIGGEERQVLAGIAKWYSPEEL 65
Query: 673 LNRYVVVVANLEPKKLRGIGSQGMLLAA--DDGERVALLMPDKEVKLGAKV 721
+ R V+VVANL+PK++ G SQGM+LAA D E+ LL + V+ G++V
Sbjct: 66 VGRLVIVVANLQPKRMAGEVSQGMVLAAPCGDSEKPVLLTVSEPVEPGSRV 116
>gb|AAF59019.1| (AE003835) CG8235 gene product [Drosophila melanogaster]
Length = 294
Score = 96.3 bits (236), Expect = 1e-18
Identities = 53/114 (46%), Positives = 73/114 (63%), Gaps = 5/114 (4%)
Query: 603 KDIKLKEKKEGKEMYVKFD----DFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEV-R 657
K+ K KEKK E D +LDLRVGKI+EV HP+AD LY+ K+D G+ R
Sbjct: 110 KEKKSKEKKPAAEKPAAAPEAPVDVGRLDLRVGKIVEVGRHPDADSLYLEKIDCGEAAPR 169
Query: 658 TLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMP 711
T+V+GL K+ EE+ NR VVV+ NL+P K+RG+ S+ M++ A E+V +L P
Sbjct: 170 TVVSGLVKFVPLEEMQNRLVVVMCNLKPAKMRGVTSEAMVMCASTPEKVEVLSP 223
>pir||F82090 methionyl-tRNA synthetase-related protein VC2336 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9656903|gb|AAF95480.1| (AE004303) methionyl-tRNA
synthetase-related protein [Vibrio cholerae]
Length = 114
Score = 94.4 bits (231), Expect = 4e-18
Identities = 46/106 (43%), Positives = 69/106 (64%), Gaps = 2/106 (1%)
Query: 618 VKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYV 677
V +DDFA+LDLR+G I+E K HP + + Y+V++ LG+++ V L YY E+LLN+ V
Sbjct: 8 VGYDDFARLDLRIGTIVEAKLHPRSTRNYIVQIALGEQMLQAVTALAPYYSAEQLLNQQV 67
Query: 678 VVVANLEPKKLRGIGSQGMLLAAD--DGERVALLMPDKEVKLGAKV 721
VV+ NL+P + G+ S MLL A+ DGE LL P + + G ++
Sbjct: 68 VVLCNLKPSLVAGVESHCMLLCAETQDGEESVLLTPQRIIANGVRI 113
>gb|AAK40936.1| Methionyl-tRNA synthetase N-term homolog (metS-like) [Sulfolobus
solfataricus]
Length = 162
Score = 92.4 bits (226), Expect = 2e-17
Identities = 50/110 (45%), Positives = 70/110 (63%), Gaps = 7/110 (6%)
Query: 618 VKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYV 677
+ DDFAKLDL+VG I+ + +L + +DLG E R ++AGL +YY PEELLN+ +
Sbjct: 53 ITIDDFAKLDLKVG-IVRQAERIEGTRLLKLLIDLGSEQRQIIAGLGEYYTPEELLNKRI 111
Query: 678 VVVANLEPKKLRGIGSQGMLLAAD------DGERVALLMPDKEVKLGAKV 721
+V+ANL+P+ +RG SQGMLLAA G + +L D EV G K+
Sbjct: 112 IVIANLKPRVIRGFESQGMLLAAGCKEDEAKGIKPRILTVDGEVPPGTKI 161
>emb|CAB57675.1| (Y18930) homolog of methionyl-tRNA synthetase [Sulfolobus
solfataricus]
Length = 162
Score = 92.4 bits (226), Expect = 2e-17
Identities = 50/110 (45%), Positives = 70/110 (63%), Gaps = 7/110 (6%)
Query: 618 VKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYV 677
+ DDFAKLDL+VG I+ + +L + +DLG E R ++AGL +YY PEELLN+ +
Sbjct: 53 ITIDDFAKLDLKVG-IVRQAERIEGTRLLKLLIDLGSEQRQIIAGLGEYYTPEELLNKRI 111
Query: 678 VVVANLEPKKLRGIGSQGMLLAAD------DGERVALLMPDKEVKLGAKV 721
+V+ANL+P+ +RG SQGMLLAA G + +L D EV G K+
Sbjct: 112 IVIANLKPRVIRGFESQGMLLAAGCKEDEAKGIKPRILTVDGEVPPGTKI 161
>gi|4507947 tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase; tyrosyl tRNA
ligase [Homo sapiens] >gi|2665519|gb|AAB88409.1|
(U89436) tyrosyl-tRNA synthetase [Homo sapiens]
Length = 528
Score = 91.7 bits (224), Expect = 3e-17
Identities = 45/78 (57%), Positives = 63/78 (80%), Gaps = 1/78 (1%)
Query: 624 AKLDLRVGKIIEVKDHPNADKLYVVKVDLGD-EVRTLVAGLKKYYKPEELLNRYVVVVAN 682
++LD+RVGKII V+ HP+AD LYV K+D+G+ E RT+V+GL ++ EEL +R VVV+ N
Sbjct: 366 SRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCN 425
Query: 683 LEPKKLRGIGSQGMLLAA 700
L+P+K+RG+ SQGMLL A
Sbjct: 426 LKPQKMRGVESQGMLLCA 443
>gb|AAB95207.1| (AF021800) multisynthetase complex auxiliary component p43
[Cricetulus griseus]
Length = 359
Score = 91.7 bits (224), Expect = 3e-17
Identities = 52/127 (40%), Positives = 79/127 (61%), Gaps = 4/127 (3%)
Query: 589 KFGDEAEVVLRRVYKDIKLKEKK---EGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKL 645
K G E + V + K + KEKK K D ++LDLR+G+I+ VK HP+AD L
Sbjct: 162 KGGGEEKKVKEKTDKKGEKKEKKLQSAAPSADSKPVDVSRLDLRIGRIVTVKKHPDADSL 221
Query: 646 YVVKVDLGDEV-RTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGE 704
YV +VD+G+ RT+++GL + +++ NR VV++ NL+P K+RGI SQ M++ A E
Sbjct: 222 YVEEVDVGEAAPRTVISGLVNHVPLDQMQNRMVVLLCNLKPAKMRGILSQAMVMCASSPE 281
Query: 705 RVALLMP 711
+V +L P
Sbjct: 282 KVEILAP 288
>gi|11423982 tyrosyl-tRNA synthetase [Homo sapiens]
Length = 500
Score = 91.7 bits (224), Expect = 3e-17
Identities = 45/78 (57%), Positives = 63/78 (80%), Gaps = 1/78 (1%)
Query: 624 AKLDLRVGKIIEVKDHPNADKLYVVKVDLGD-EVRTLVAGLKKYYKPEELLNRYVVVVAN 682
++LD+RVGKII V+ HP+AD LYV K+D+G+ E RT+V+GL ++ EEL +R VVV+ N
Sbjct: 338 SRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCN 397
Query: 683 LEPKKLRGIGSQGMLLAA 700
L+P+K+RG+ SQGMLL A
Sbjct: 398 LKPQKMRGVESQGMLLCA 415
>gb|AAC82467.1| (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRNA ligase [Bos
taurus]
Length = 528
Score = 90.9 bits (222), Expect = 5e-17
Identities = 44/78 (56%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Query: 624 AKLDLRVGKIIEVKDHPNADKLYVVKVDLGD-EVRTLVAGLKKYYKPEELLNRYVVVVAN 682
++LD+RVGK+I V HP+AD LYV K+D+G+ E RT+V+GL ++ EEL +R VVV+ N
Sbjct: 366 SRLDIRVGKVISVDKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCN 425
Query: 683 LEPKKLRGIGSQGMLLAA 700
L+P+K+RG+ SQGMLL A
Sbjct: 426 LKPQKMRGVKSQGMLLCA 443
>gi|6679639 endothelial monocyte activating polypeptide 2 [Mus musculus]
>gi|1083307|pir||A55053 endothelial monocyte-activating
protein II precursor - mouse >gi|498912|gb|AAA62203.1|
(U10118) endothelial-monocyte activating polypeptide II
[Mus musculus]
Length = 310
Score = 88.2 bits (215), Expect = 3e-16
Identities = 52/126 (41%), Positives = 79/126 (62%), Gaps = 4/126 (3%)
Query: 589 KFGDEAEVVLRRVYKDIKLKEKKEGKEMYV--KFDDFAKLDLRVGKIIEVKDHPNADKLY 646
K G+E +V + K K KEK++ K D ++LDLR+G I+ K HP+AD LY
Sbjct: 115 KAGEEKKVKEKTEKKGEK-KEKQQSAAASTDSKPIDASRLDLRIGCIVTAKKHPDADSLY 173
Query: 647 VVKVDLGDEV-RTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGER 705
V +VD+G+ RT+V+GL + E++ NR VV++ NL+P K+RG+ SQ M++ A E+
Sbjct: 174 VEEVDVGEAAPRTVVSGLVNHVPLEQMQNRMVVLLCNLKPAKMRGVLSQAMVMCASSPEK 233
Query: 706 VALLMP 711
V +L P
Sbjct: 234 VEILAP 239
>gi|4758266 small inducible cytokine subfamily E, member 1; endothelial
monocyte-activating polypeptide [Homo sapiens]
>gi|498910|gb|AAA62202.1| (U10117) endothelial-monocyte
activating polypeptide II [Homo sapiens]
Length = 312
Score = 87.8 bits (214), Expect = 4e-16
Identities = 47/113 (41%), Positives = 73/113 (64%), Gaps = 7/113 (6%)
Query: 606 KLKEKKEGKEMYV------KFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEV-RT 658
K EKKE K+ + K D ++LDLR+G II + HP+AD LYV +VD+G+ RT
Sbjct: 129 KKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRT 188
Query: 659 LVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMP 711
+V+GL + E++ NR V+++ NL+P K+RG+ SQ M++ A E++ +L P
Sbjct: 189 VVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAP 241
>pir||B55053 endothelial monocyte-activating protein II precursor - human
Length = 310
Score = 87.8 bits (214), Expect = 4e-16
Identities = 47/113 (41%), Positives = 73/113 (64%), Gaps = 7/113 (6%)
Query: 606 KLKEKKEGKEMYV------KFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEV-RT 658
K EKKE K+ + K D ++LDLR+G II + HP+AD LYV +VD+G+ RT
Sbjct: 127 KKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRT 186
Query: 659 LVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMP 711
+V+GL + E++ NR V+++ NL+P K+RG+ SQ M++ A E++ +L P
Sbjct: 187 VVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAP 239
>gb|AAF49462.1| (AE003527) CG4561 gene product [Drosophila melanogaster]
Length = 525
Score = 87.8 bits (214), Expect = 4e-16
Identities = 52/154 (33%), Positives = 89/154 (57%), Gaps = 18/154 (11%)
Query: 573 LDKYYKREDV----IRVAKEKFGDEAEVVLRRVYKDIKLKEK-----------KEGKEMY 617
L+KYY + + ++ EK+ + +R+ +++ +L++ K G
Sbjct: 297 LEKYYAEDKLHPGDLKATVEKYINRLLDPIRKAFENPELQKLSAAAYPPPAKVKAGAAPA 356
Query: 618 VKFDDFA--KLDLRVGKIIEVKDHPNADKLYVVKVDLGD-EVRTLVAGLKKYYKPEELLN 674
D+ A +LD+RVGK++EV HP+AD LYV+K+DL + + RT+++GL K+ EEL
Sbjct: 357 AGADEDAPHRLDIRVGKVVEVARHPDADTLYVLKIDLAEAQPRTIISGLVKFVTEEELNQ 416
Query: 675 RYVVVVANLEPKKLRGIGSQGMLLAADDGERVAL 708
R V V+ NL+P K+RGI S+GM+L + + +
Sbjct: 417 RLVAVLCNLKPSKMRGILSEGMVLCTSNADHTVV 450
>gi|11435649 small inducible cytokine subfamily E, member 1 [Homo sapiens]
Length = 321
Score = 87.8 bits (214), Expect = 4e-16
Identities = 47/113 (41%), Positives = 73/113 (64%), Gaps = 7/113 (6%)
Query: 606 KLKEKKEGKEMYV------KFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEV-RT 658
K EKKE K+ + K D ++LDLR+G II + HP+AD LYV +VD+G+ RT
Sbjct: 138 KKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRT 197
Query: 659 LVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMP 711
+V+GL + E++ NR V+++ NL+P K+RG+ SQ M++ A E++ +L P
Sbjct: 198 VVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAP 250
>gi|6321333 G4 nucleic acid binding protein, involved in tRNA aminoacylation;
Arc1p [Saccharomyces cerevisiae]
>gi|1730165|sp|P46672|G4P1_YEAST GU4 NUCLEIC-BINDING
PROTEIN 1 (P42) (ARC1 PROTEIN) >gi|2131260|pir||S64113
ARC1 protein - yeast (Saccharomyces cerevisiae)
>gi|1310719|emb|CAA66247.1| (X97644) G4p1-like
[Saccharomyces cerevisiae] >gi|1322648|emb|CAA96812.1|
(Z72627) ORF YGL105w [Saccharomyces cerevisiae]
>gi|1620460|emb|CAA64750.1| (X95481) Arc1p
[Saccharomyces]
Length = 376
Score = 86.2 bits (210), Expect = 1e-15
Identities = 57/157 (36%), Positives = 88/157 (55%), Gaps = 15/157 (9%)
Query: 580 EDVIRVAKEKF---GDEAEVVLRRVYKDIKLKEK-------KEGKEMYVKFDDFAK---L 626
EDV + AK++ G E L+++ ++ K K+ K+ +E K + K +
Sbjct: 150 EDVSKKAKKQDHPRGKPDEETLKKLREEAKAKKAAKKAANAKQQQEQQNKAPEKPKPSAI 209
Query: 627 DLRVGKIIEVKDHPNADKLYVVKVDLGDEV--RTLVAGLKKYYKPEELLNRYVVVVANLE 684
D RVG I + HP+AD LYV +D+GDE RT+ +GL K++ + + RYVVVV NL+
Sbjct: 210 DFRVGFIQKAIKHPDADSLYVSTIDVGDEEGPRTVCSGLVKHFPLDAMQERYVVVVCNLK 269
Query: 685 PKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAKV 721
P +RGI S M+L + ++V + P K+ K G KV
Sbjct: 270 PVNMRGIKSTAMVLCGSNDDKVEFVEPPKDSKAGDKV 306
>gb|AAC49072.1| (U31348) G4p1 [Saccharomyces cerevisiae]
Length = 375
Score = 85.0 bits (207), Expect = 3e-15
Identities = 50/136 (36%), Positives = 79/136 (57%), Gaps = 3/136 (2%)
Query: 588 EKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYV 647
+K +EA+ +L K K+++E + + + +D RVG I + HP+AD LYV
Sbjct: 171 KKLREEAKALLA-AKKAANAKQQQEQQNKAPEKPKPSAIDFRVGFIQKAIKHPDADSLYV 229
Query: 648 VKVDLGDEV--RTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGER 705
+D+GDE RT+ +GL K++ + + RYVVVV NL+P +RGI S M+L + ++
Sbjct: 230 STIDVGDEEGPRTVCSGLVKHFPLDAMQERYVVVVCNLKPVNMRGIKSTAMVLCGSNDDK 289
Query: 706 VALLMPDKEVKLGAKV 721
V + P K+ K G KV
Sbjct: 290 VEFVEPPKDSKAGDKV 305
>pdb|1EUJ|A Chain A, A Novel Anti-Tumor Cytokine Contains A Rna-Binding Motif
Present In Aminoacyl-Trna Synthetases
>gi|10120517|pdb|1EUJ|B Chain B, A Novel Anti-Tumor
Cytokine Contains A Rna-Binding Motif Present In
Aminoacyl-Trna Synthetases >gi|1619592|emb|CAA69993.1|
(Y08737) human EMAPII [synthetic construct]
Length = 166
Score = 84.7 bits (206), Expect = 3e-15
Identities = 40/91 (43%), Positives = 64/91 (69%), Gaps = 1/91 (1%)
Query: 622 DFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEV-RTLVAGLKKYYKPEELLNRYVVVV 680
D ++LDLR+G II + HP+AD LYV +VD+G+ RT+V+GL + E++ NR V+++
Sbjct: 5 DVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILL 64
Query: 681 ANLEPKKLRGIGSQGMLLAADDGERVALLMP 711
NL+P K+RG+ SQ M++ A E++ +L P
Sbjct: 65 CNLKPAKMRGVLSQAMVMCASSPEKIEILAP 95
>pir||I40248 methionyl tRNA synthetase - Lyme disease spirochete (fragment)
>gi|476006|gb|AAC41404.1| (L32146) methionyl tRNA
synthetase [Borrelia burgdorferi]
Length = 115
Score = 83.1 bits (202), Expect = 1e-14
Identities = 47/126 (37%), Positives = 66/126 (52%), Gaps = 16/126 (12%)
Query: 247 KGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPFHAIF 306
+ KV YVWF+APIGYISIT K W+ +W N D Q ++ FIGKDNI FH I
Sbjct: 3 ENKVFYVWFDAPIGYISITKNIIK------NWESWWKNND-QVNLVQFIGKDNILFHTII 55
Query: 307 WPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDV-FPAD 365
+P + E W + + ++EYL E KFS S I+ ++ + P+D
Sbjct: 56 FPCIEIG--------SEENWTILNQLSSSEYLNYENLKFSKSEGTGIFGNDAITTGIPSD 107
Query: 366 YLRYYL 371
R+Y+
Sbjct: 108 IWRFYI 113
>sp|P57519|SYL_BUCAI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|10039108|dbj|BAB13142.1| (AP001119) leucyl-tRNA
synthetase [Buchnera sp. APS]
Length = 859
Score = 82.3 bits (200), Expect = 2e-14
Identities = 78/315 (24%), Positives = 128/315 (39%), Gaps = 47/315 (14%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+Y LPY +G +H GH+ Y +D+ RY R+ G++V+ G D G P A++
Sbjct: 34 KYYCLPMLPYPSGKLHMGHVRN-YTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIR 92
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGR--TELPIHYKLSQEFFLKAYENGHLVKK 120
P + + +K Q S+D+ T P +Y Q FF K YE + KK
Sbjct: 93 NNTDPFSWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKK 152
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
+ +C +DK L + VI C C C I
Sbjct: 153 NSLVNWCSYDKTVLANEQVIDGC-----------------------------CWRCQNKI 183
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQP-WKPNVKNMVLSWIE--EGLEERAITRDLNWGI 237
+ ++IK++++AE L + ++K W NVKNM +WI +G E + +
Sbjct: 184 RIKQIPQWFIKIRNYAESLYQDLKKLTHWPENVKNMQRNWIGRIKGFEITLNVFNTCQKL 243
Query: 238 PVPLDEEDMKGKVLYVWFEAPIGYISIT-----------IEHFKRIGKPNEWKKYWLNID 286
V D+ V Y+ + +SI I+ ++ I + ++K + I+
Sbjct: 244 KVFTQRLDLLMGVTYISISS-CHKLSINLSKKNELIKKFIKKYRYISQEEQYKVKYTGIN 302
Query: 287 GQTRVIHFIGKDNIP 301
V+H I K IP
Sbjct: 303 TNLFVVHPITKKTIP 317
>sp|P43827|SYL_HAEIN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|1074962|pir||H64102 leucine--tRNA ligase (EC
6.1.1.4) - Haemophilus influenzae (strain Rd KW20)
>gi|1573943|gb|AAC22581.1| (U32774) leucyl-tRNA
synthetase (leuS) [Haemophilus influenzae Rd]
Length = 861
Score = 81.9 bits (199), Expect = 2e-14
Identities = 63/228 (27%), Positives = 99/228 (42%), Gaps = 35/228 (15%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+Y S PY +G +H GH+ Y D+ RY R+ G++V+ G D G P A+K
Sbjct: 34 KYYCLSMFPYPSGRLHMGHVRN-YTIGDVISRYQRMLGKNVLQPFGWDAFGLPAEGAAIK 92
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGR--TELPIHYKLSQEFFLKAYENGHLVKK 120
+P + E +K Q FD+ T P +YK Q FF + Y+ G + KK
Sbjct: 93 NKTAPAKWTYENIAYMKKQLQLLGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKK 152
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
+ +C +D+ L A +Q + C C C P+
Sbjct: 153 TSTVNWCPNDETVL-------------ANEQVHEGC----------------CWRCDTPV 183
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEKQP-WKPNVKNMVLSWI--EEGLE 225
++ ++IK+ D+AE+L ++ P W VK M +WI EG+E
Sbjct: 184 EQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVE 231
>sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437543|pir||F72408 leucine--tRNA ligase (EC
6.1.1.4) - Thermotoga maritima (strain MSB8)
>gi|4980663|gb|AAD35261.1|AE001702_1 (AE001702)
leucyl-tRNA synthetase [Thermotoga maritima]
Length = 824
Score = 81.5 bits (198), Expect = 3e-14
Identities = 60/221 (27%), Positives = 97/221 (43%), Gaps = 33/221 (14%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
+Y PY +G +H GH+ Y+ DI RY R++G +V+ G D G P A++
Sbjct: 33 KYYALVMFPYPSGTLHVGHVKN-YVIGDIVARYKRMRGYNVLHPFGYDAFGLPAENAAIE 91
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGR--TELPIHYKLSQEFFLKAYENGHLVKK 120
+G P E + I+ ++ IS+D+ T +YK +Q FL+ Y+NG KK
Sbjct: 92 KGIHPEEWTRKNIATIRQQVKKLGISYDWSREIATCDEEYYKWTQWIFLQLYKNGLAYKK 151
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
+ + CP C L E + + +C CG +
Sbjct: 152 ----------------KAAVNWCPKCKT-------------VLANEQVKDGKCERCGTSV 182
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEK-QPWKPNVKNMVLSWI 220
+ R ++ K+ D+AERL ++K W +VK M +WI
Sbjct: 183 TIRHLEQWFFKITDYAERLLNDLDKLTGWPEHVKTMQRNWI 223
>emb|CAA10534.1| (AJ131940) aminoacyl-tRNA synthetase cofactor [Euplotes
octocarinatus] >gi|4140279|emb|CAA10535.1| (AJ131941)
aminoacyl-tRNA synthetase cofactor [Euplotes
octocarinatus] >gi|4140281|emb|CAA10536.1| (AJ131942)
aminoacyl-tRNA synthetase cofactor [Euplotes
octocarinatus]
Length = 441
Score = 81.5 bits (198), Expect = 3e-14
Identities = 50/152 (32%), Positives = 84/152 (54%), Gaps = 8/152 (5%)
Query: 567 EGARILLDKYYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMY------VKF 620
EG + K K + + +EK D E+ KD K K++ K+ K
Sbjct: 221 EGPEEIKSKDVKHPEKNKDEEEKKVDN-EIKPSEGKKDKKSKQQNSSKKQSEQPKKEAKV 279
Query: 621 DDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDE-VRTLVAGLKKYYKPEELLNRYVVV 679
+ ++LD+R+GKI ++ HP +D LY ++D+GDE R + +GL+++ E++ N V+V
Sbjct: 280 EPVSQLDIRIGKITKIWKHPESDNLYCEEIDIGDEKPRQIASGLQQFVPIEQMENALVLV 339
Query: 680 VANLEPKKLRGIGSQGMLLAADDGERVALLMP 711
+ANL+P+KL G SQGM+L A + + +P
Sbjct: 340 LANLKPRKLGGFESQGMVLMAGNNDYTYFELP 371
>sp|O66680|SYLA_AQUAE LEUCYL-TRNA SYNTHETASE ALPHA SUBUNIT (LEUCINE--TRNA LIGASE ALPHA
SUBUNIT) (LEURS) >gi|7519891|pir||D70331 leucine--tRNA
ligase (EC 6.1.1.4) alpha chain - Aquifex aeolicus
>gi|2983033|gb|AAC06643.1| (AE000685) leucyl-tRNA
synthetase alpha subunit [Aquifex aeolicus]
Length = 634
Score = 80.4 bits (195), Expect = 7e-14
Identities = 71/271 (26%), Positives = 114/271 (41%), Gaps = 59/271 (21%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
++ V PY +G IH GH+ Y D RYL+++G++++ G D G P A+K
Sbjct: 33 KFYVLEMFPYPSGRIHMGHVRN-YTIGDAIARYLKMRGKNILHPMGWDAFGLPAENAAIK 91
Query: 63 EGRSPR----EIVDEFHEQIKITFQRAKISFDFFGRTEL----PIHYKLSQEFFLKAYEN 114
G P E +D +Q+KI + F + E+ P +YK +Q FLK E
Sbjct: 92 HGIHPAKWTYENIDYMKKQLKI------LGFSYDWDREIATCDPEYYKWNQWIFLKMLER 145
Query: 115 GHLVKKVTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCA 174
G +K K +C HD+ L + E +I +C
Sbjct: 146 GIAYRKTAKVNWCPHDQTVLAN-----------------------------EQVIEGKCW 176
Query: 175 ICGRPISFRDSAHYYIKMQDFAERLKRWIEK--QPWKPNVKNMVLSWIEEGLEERAITR- 231
CG PI ++ +++++ +A+RL ++K W V +WI G E A+ R
Sbjct: 177 RCGTPIVQKEVPSWFLRITAYADRLLEDLKKLEGKWPERVIAQQRNWI--GRSEGALIRF 234
Query: 232 ---------DLNWGIPVPLDEEDMKGKVLYV 253
LN +P L E +K K +Y+
Sbjct: 235 YVEIEEPEKFLNC-VPEELKETLLKEKRIYI 264
>gb|AAD32818.1|AC007660_19 (AC007660) putative methionyl-tRNA synthetase [Arabidopsis
thaliana]
Length = 440
Score = 79.2 bits (192), Expect = 2e-13
Identities = 48/125 (38%), Positives = 76/125 (60%), Gaps = 6/125 (4%)
Query: 603 KDIKLKEKKEGKEMYVKFD---DFAKLDLRVGKIIEVKDHPNADKLYVVKVDLG-DEVRT 658
KD K ++KK + K + + L+++VG I + HP+AD L V ++D+G D+VR
Sbjct: 257 KDAKKEKKKPAEPEPAKKEAELSVSLLNIQVGLIRKAWKHPSADSLLVEEIDVGEDKVRQ 316
Query: 659 LVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAA--DDGERVALLMPDKEVK 716
+V+GL K+ PE+L NR V ++ N++P KLR + SQG++L A +D V L+P K
Sbjct: 317 VVSGLAKFCSPEDLTNRLVALITNVKPGKLRDVMSQGLVLCASSEDHSVVEPLLPPAGAK 376
Query: 717 LGAKV 721
G +V
Sbjct: 377 PGERV 381
>emb|CAC12407.1| (AL445067) fragment of probable methionine--tRNA ligase
[Thermoplasma acidophilum]
Length = 107
Score = 79.2 bits (192), Expect = 2e-13
Identities = 38/106 (35%), Positives = 65/106 (60%)
Query: 616 MYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNR 675
M + + F +LD+R K++ + + L + VDLG E + +++ + YY P +L+ +
Sbjct: 1 MEIDINYFRQLDIRAVKVVSAEKVEKSRSLLRLIVDLGGEQKQIISSIADYYNPSDLVGK 60
Query: 676 YVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAKV 721
++++ NL+P K G+ SQGMLLA D+ + V LL D EVK G++V
Sbjct: 61 TIIILNNLKPAKFMGLESQGMLLAVDNEDGVKLLTVDGEVKPGSRV 106
>pir||A64379 isoleucine--tRNA ligase (EC 6.1.1.5) - Methanococcus jannaschii
Length = 942
Score = 78.8 bits (191), Expect = 2e-13
Identities = 111/497 (22%), Positives = 200/497 (39%), Gaps = 67/497 (13%)
Query: 176 CGRPISFRD-SAHYYIKMQD--FAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRD 232
CG P + ++IK D + E + I+K + P V + ++++A R
Sbjct: 442 CGTPCIVKMVKGQWFIKYSDEKWKELAHKCIDKMRFIPENLRQVFHEKIDWMKDKACVRR 501
Query: 233 LNWGIPVPLDE----EDMKGKVLYVWFEAPIGYIS--------ITIEHFKRI--GKPNEW 278
G P +E E + +Y + YI+ +T+E F + GK +
Sbjct: 502 RGLGTKFPFEEGWVIESLSDSTIYPAYYTVAKYINQHNIKPEQLTLELFDYVFLGK-GDV 560
Query: 279 KKYWLNIDGQTRVIHFIGKDNIPFHAIFW--------PAFLMAYGKYKDEEVEAEWNLPY 330
K +I + K+ I ++ + W P L Y + + E P
Sbjct: 561 DKIAKETGIPKDIIEGMRKEFIYYYPVDWRCSAKDLIPNHLTFY-IFNHVAIFPEEFWPR 619
Query: 331 DIPANEYLTLEGKKFSTSRNWAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKV 390
I N Y+T+EGKK S S+ + V E + F AD R+Y+TT +D+D F +
Sbjct: 620 GIVVNGYVTIEGKKLSKSKGPVLPVLEVAEKFGADVGRFYITTCAELPQDADIKFKE--- 676
Query: 391 RINEELVNNLGNFVHRALTFVNRYFDGVVPERGELDE----LDREALEEIEKAFKEVGEL 446
+ N + R F + RGE E +D+ L + KA K+ E
Sbjct: 677 ------MENTKKVLERLYLFAKE----IAERRGETGEEFSYIDKWLLSRLYKAVKQYDEY 726
Query: 447 IMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEP 506
+ N+ + A + L K + R G + + + ++ + L+ P
Sbjct: 727 MENFELRKAGILLYQLLD-------------DLKWYRRRGGNNIRVLEEFLEVIIKLMMP 773
Query: 507 FLPDASEKIWHLLN----LDEVKRWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMA 562
F P E++W +L + K E +E ++ K E K V +D I I+N +A
Sbjct: 774 FTPHLCEEMWEILGKEGFVSLAKFPEVKEEFINDEIEKGEEYLKAVMED--IKEIIN-VA 830
Query: 563 KGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDD 622
K P+ + +K E ++++ KE G + ++ + K+ + +K GKE+ +
Sbjct: 831 KVQPKRIYLYTADDWKYE-ILKIIKENEGKTIKELMPIIMKNPEF--RKYGKEIPKLVNQ 887
Query: 623 FAKLDLRVGKIIEVKDH 639
KL+ + +EV ++
Sbjct: 888 LIKLNAEIINEVEVLEN 904
>sp|Q58050|SYL_METJA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|2826301|gb|AAB98628.1| (U67511) leucyl-tRNA
synthetase (leuS) [Methanococcus jannaschii]
Length = 942
Score = 78.8 bits (191), Expect = 2e-13
Identities = 111/497 (22%), Positives = 200/497 (39%), Gaps = 67/497 (13%)
Query: 176 CGRPISFRD-SAHYYIKMQD--FAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRD 232
CG P + ++IK D + E + I+K + P V + ++++A R
Sbjct: 442 CGTPCIVKMVKGQWFIKYSDEKWKELAHKCIDKMRFIPENLRQVFHEKIDWMKDKACVRR 501
Query: 233 LNWGIPVPLDE----EDMKGKVLYVWFEAPIGYIS--------ITIEHFKRI--GKPNEW 278
G P +E E + +Y + YI+ +T+E F + GK +
Sbjct: 502 RGLGTKFPFEEGWVIESLSDSTIYPAYYTVAKYINQHNIKPEQLTLELFDYVFLGK-GDV 560
Query: 279 KKYWLNIDGQTRVIHFIGKDNIPFHAIFW--------PAFLMAYGKYKDEEVEAEWNLPY 330
K +I + K+ I ++ + W P L Y + + E P
Sbjct: 561 DKIAKETGIPKDIIEGMRKEFIYYYPVDWRCSAKDLIPNHLTFY-IFNHVAIFPEEFWPR 619
Query: 331 DIPANEYLTLEGKKFSTSRNWAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKV 390
I N Y+T+EGKK S S+ + V E + F AD R+Y+TT +D+D F +
Sbjct: 620 GIVVNGYVTIEGKKLSKSKGPVLPVLEVAEKFGADVGRFYITTCAELPQDADIKFKE--- 676
Query: 391 RINEELVNNLGNFVHRALTFVNRYFDGVVPERGELDE----LDREALEEIEKAFKEVGEL 446
+ N + R F + RGE E +D+ L + KA K+ E
Sbjct: 677 ------MENTKKVLERLYLFAKE----IAERRGETGEEFSYIDKWLLSRLYKAVKQYDEY 726
Query: 447 IMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEP 506
+ N+ + A + L K + R G + + + ++ + L+ P
Sbjct: 727 MENFELRKAGILLYQLLD-------------DLKWYRRRGGNNIRVLEEFLEVIIKLMMP 773
Query: 507 FLPDASEKIWHLLN----LDEVKRWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMA 562
F P E++W +L + K E +E ++ K E K V +D I I+N +A
Sbjct: 774 FTPHLCEEMWEILGKEGFVSLAKFPEVKEEFINDEIEKGEEYLKAVMED--IKEIIN-VA 830
Query: 563 KGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDD 622
K P+ + +K E ++++ KE G + ++ + K+ + +K GKE+ +
Sbjct: 831 KVQPKRIYLYTADDWKYE-ILKIIKENEGKTIKELMPIIMKNPEF--RKYGKEIPKLVNQ 887
Query: 623 FAKLDLRVGKIIEVKDH 639
KL+ + +EV ++
Sbjct: 888 LIKLNAEIINEVEVLEN 904
>pir||G82260 leucyl-tRNA synthetase VC0956 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655415|gb|AAF94118.1| (AE004177)
leucyl-tRNA synthetase [Vibrio cholerae]
Length = 894
Score = 78.8 bits (191), Expect = 2e-13
Identities = 66/260 (25%), Positives = 107/260 (40%), Gaps = 35/260 (13%)
Query: 3 RYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALK 62
++ S PY +G +H GH+ Y D+ R+ RL+G++V+ G D G P A+K
Sbjct: 70 KFYCLSMFPYPSGRLHMGHVRN-YTIGDVVSRFQRLQGKNVLQPIGWDAFGLPAENAAVK 128
Query: 63 EGRSPREIVDEFHEQIKITFQRAKISFDFFGR--TELPIHYKLSQEFFLKAYENGHLVKK 120
+P E E +K + +D+ T P +Y+ QEFF K + G + KK
Sbjct: 129 NNTAPAPWTYENIEYMKNQLKLLGFGYDWNREFATCRPEYYRWEQEFFTKLFAKGLVYKK 188
Query: 121 VTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPI 180
+ +C +D+ L A +Q D C C C P+
Sbjct: 189 TSSVNWCPNDQTVL-------------ANEQVEDGC----------------CWRCDTPV 219
Query: 181 SFRDSAHYYIKMQDFAERLKRWIEK-QPWKPNVKNMVLSWI--EEGLEERAITRDLNWGI 237
++ ++IK+ +A+ L ++ W VK M +WI EG+E + + N +
Sbjct: 220 EQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTDL 279
Query: 238 PVPLDEEDMKGKVLYVWFEA 257
V D V YV A
Sbjct: 280 EVYTTRPDTLMGVTYVGIAA 299
>pir||T47822 hypothetical protein F24G16.250 - Arabidopsis thaliana
>gi|7019692|emb|CAB75817.1| (AL138647) putative protein
[Arabidopsis thaliana]
Length = 273
Score = 78.0 bits (189), Expect = 3e-13
Identities = 45/99 (45%), Positives = 64/99 (64%), Gaps = 3/99 (3%)
Query: 626 LDLRVGKIIEVKDHPNADKLYVVKVDLGD-EVRTLVAGLKKYYKPEELLNRYVVVVANLE 684
LD++VG+I++ H AD LYV +VD+G+ E R + +GL KY + L VVV+ANL+
Sbjct: 109 LDIKVGRIVKAWQHEEADSLYVEEVDIGEAEPRIICSGLVKYVPLDLLQGASVVVLANLK 168
Query: 685 PKKLRGIGSQGMLLAADDG--ERVALLMPDKEVKLGAKV 721
P+ +RG+ S GMLLAA D E V LL+P + G +V
Sbjct: 169 PRNMRGVKSCGMLLAASDAAHENVELLVPPEGSVPGDRV 207
>sp|Q9ZJ63|SYL_HELPJ LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437531|pir||G71805 leucine--tRNA ligase (EC
6.1.1.4) - Helicobacter pylori (strain J99)
>gi|4156066|gb|AAD07021.1| (AE001567) LEUCYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 806
Score = 77.3 bits (187), Expect = 6e-13
Identities = 60/221 (27%), Positives = 93/221 (41%), Gaps = 38/221 (17%)
Query: 6 VTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEGR 65
+ S LPY +G IH GH+ Y D RY RL +V+ G D G P A+K G
Sbjct: 33 ILSMLPYPSGEIHMGHVRN-YTIGDALARYYRLHHYNVLHPMGFDSFGMPAENAAIKHGI 91
Query: 66 SPREIVDEFHEQIKITFQRAKISF----DFFGRTELPIHYKLSQEFFLKAYENGHLVKKV 121
P+ E E ++ F+ SF +F T P + K Q+FF+ +E G + +K
Sbjct: 92 HPKTWTYENIEAMQKEFEALGFSFSKNREF--ATSDPDYTKFEQQFFIDLWEKGLIYRKK 149
Query: 122 TKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPIS 181
+C +DK L + E +I+ RC C +
Sbjct: 150 AMLNWCPNDKTVLAN-----------------------------EQVIDGRCWRCDTEVI 180
Query: 182 FRDSAHYYIKMQDFAERLKRWIE--KQPWKPNVKNMVLSWI 220
++ YY+K+ ++AE L + +E + W V M +WI
Sbjct: 181 QKELYQYYLKITNYAEELLKDLETLENHWPSQVLTMQKNWI 221
>pir||H75156 methionine--tRNA ligase truncated homolog PAB0278 [imported] -
Pyrococcus abyssi (strain Orsay)
>gi|5457845|emb|CAB49335.1| (AJ248284) fragment of
methionyl-tRNA synthetase [Pyrococcus abyssi]
Length = 109
Score = 76.1 bits (184), Expect = 1e-12
Identities = 40/102 (39%), Positives = 60/102 (58%), Gaps = 1/102 (0%)
Query: 621 DDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYVVVV 680
++F K D+RVG + + + KL + VD G E RT++ G+ Y PE+L + + V
Sbjct: 7 EEFWKFDMRVGLVKKAEKLKRTRKLIRLDVDFGSEERTIITGIADQYNPEDLEGKKFIFV 66
Query: 681 ANLEPKKLRGIGSQGMLLAADDGERVALLMP-DKEVKLGAKV 721
NL+PKK G+ SQGMLL A+ + L+P +EV +G KV
Sbjct: 67 LNLKPKKFSGVESQGMLLVAETEDGKVYLIPVPEEVPVGTKV 108
>emb|CAA75164.1| (Y14947) endothelial-monocyte-activating polypeptide related
protein [Geodia cydonium]
Length = 149
Score = 75.7 bits (183), Expect = 2e-12
Identities = 38/95 (40%), Positives = 61/95 (64%), Gaps = 1/95 (1%)
Query: 628 LRVGKIIEVKDHPNADKLYVVKVDLGDEV-RTLVAGLKKYYKPEELLNRYVVVVANLEPK 686
+R+G+I V+ HP+AD LYV ++D+G+E RT+ +GL + E + NR VVV+ NL+P
Sbjct: 1 MRIGRITSVERHPDADTLYVEQIDVGEEKPRTVCSGLVTHVAIETMNNRLVVVLCNLKPV 60
Query: 687 KLRGIGSQGMLLAADDGERVALLMPDKEVKLGAKV 721
K+RG+ S+ M++ A E + +L P G +V
Sbjct: 61 KMRGVTSEAMVMCASSPENIEILDPPDSCVPGDRV 95
>sp|O83595|SYL_TREPA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437534|pir||C71305 leucine--tRNA ligase (EC
6.1.1.4) - syphilis spirochete
>gi|3322882|gb|AAC65562.1| (AE001234) leucyl-tRNA
synthetase (leuS) [Treponema pallidum]
Length = 878
Score = 74.1 bits (179), Expect = 5e-12
Identities = 63/224 (28%), Positives = 91/224 (40%), Gaps = 39/224 (17%)
Query: 3 RYMVTSALPYANGP-IHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
R V PY + +H GH G Y DI+ RYLR+ G +V+ G D G P AL
Sbjct: 35 RAYVLDMFPYPSAQGLHVGHPEG-YTATDIYCRYLRMGGYNVLHPMGFDAFGLPAENFAL 93
Query: 62 KEGRSPREIVDEFHEQIKITFQRAKISFDFFGR--TELPIHYKLSQEFFLKAYENGHLVK 119
K G PR + + Q S+D+ T P +Y+ +Q FLK YE G L
Sbjct: 94 KTGTHPRVSTSANCDTFRRQIQSFGFSYDWEREISTADPEYYRWTQWLFLKLYEKG-LAY 152
Query: 120 KVTKQAYCEHDKMFLPDRFVIGTCPYCG---AEDQKGDQCEVCGRPLTPEILINPRCAIC 176
+ T I CP C A ++ D C C C
Sbjct: 153 EATAP---------------INWCPSCKTGLANEEVRDAC----------------CERC 181
Query: 177 GRPISFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWI 220
G ++ R + +++ +AERL +++ W +VK M +WI
Sbjct: 182 GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWI 225
>gb|AAG20349.1| (AE005108) leucine-tRNA synthetase; LeuS [Halobacterium sp. NRC-1]
Length = 885
Score = 73.4 bits (177), Expect = 9e-12
Identities = 56/218 (25%), Positives = 94/218 (42%), Gaps = 31/218 (14%)
Query: 6 VTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEGR 65
V + PY +G +H GH+ Y D F RY R+ GEDV+ G D G P A +
Sbjct: 38 VLAMFPYTSGQLHMGHVRN-YAITDAFARYRRMDGEDVLHPMGWDSFGLPAENAANERDT 96
Query: 66 SPREIVDEFHEQIKITFQRAKISFDFFGR--TELPIHYKLSQEFFLKAYENGHLVKKVTK 123
+PRE + +Q++ F+ +D+ T P +YK +Q F + + G + ++
Sbjct: 97 NPREWTERCIDQMRDQFEALGFGYDWEREITTCDPDYYKWNQWLFTEFRDAGLVDRRAAT 156
Query: 124 QAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFR 183
+C + L D E +GD E+C R C P++ R
Sbjct: 157 VNWCPSCETVLAD------------EQVEGDD-ELCWR--------------CDTPVTER 189
Query: 184 DSAHYYIKMQDFAERLKRWI-EKQPWKPNVKNMVLSWI 220
D ++ + +A+ L + E W NV++M +W+
Sbjct: 190 DLDQWFFETTAYADELLDGLDELDGWPSNVRDMQRNWV 227
>sp|P36430|SYL_BACSU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437539|pir||D69650 leucine--tRNA ligase (EC
6.1.1.4) - Bacillus subtilis >gi|2293181|gb|AAC00259.1|
(AF008220) leucine tRNA synthetase [Bacillus subtilis]
>gi|2635516|emb|CAB15010.1| (Z99119) leucyl-tRNA
synthetase [Bacillus subtilis]
Length = 804
Score = 73.0 bits (176), Expect = 1e-11
Identities = 61/225 (27%), Positives = 92/225 (40%), Gaps = 41/225 (18%)
Query: 3 RYMVTSALPYANGP-IHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
++ PY +G +H GH G Y DI R R++G DV+ G D G P AL
Sbjct: 32 KFYALDMFPYPSGAGLHVGHPEG-YTATDILSRMKRMQGYDVLHPMGWDAFGLPAEQYAL 90
Query: 62 KEGRSP----REIVDEFHEQIKITFQRAKISFDFFG--RTELPIHYKLSQEFFLKAYENG 115
G P ++ +D F QI Q S+D+ T P +YK +Q FLK YE G
Sbjct: 91 DTGNDPAVFTKQNIDNFRRQI----QALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKG 146
Query: 116 HLVKKVTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAI 175
+ D + CP G L E +I+ +
Sbjct: 147 ----------------LAYVDEVPVNWCP-------------ALGTVLANEEVIDGKSER 177
Query: 176 CGRPISFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWI 220
G P+ R + +K+ +A+RL +E+ W ++K+M +WI
Sbjct: 178 GGHPVERRPMKQWMLKITAYADRLLEDLEELDWPESIKDMQRNWI 222
>pir||A41882 leucine--tRNA ligase (EC 6.1.1.4) - Bacillus subtilis
>gi|143148|gb|AAA22571.1| (M88581) transfer RNA-Leu
synthetase [Bacillus subtilis]
Length = 804
Score = 72.2 bits (174), Expect = 2e-11
Identities = 61/225 (27%), Positives = 92/225 (40%), Gaps = 41/225 (18%)
Query: 3 RYMVTSALPYANGP-IHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
++ PY +G +H GH G Y DI R R++G DV+ G D G P AL
Sbjct: 32 KFYALDMFPYPSGAGLHVGHPEG-YTATDILSRMKRMQGYDVLHPMGWDAFGLPAEQYAL 90
Query: 62 KEGRSP----REIVDEFHEQIKITFQRAKISFDFFG--RTELPIHYKLSQEFFLKAYENG 115
G P ++ +D F QI Q S+D+ T P +YK +Q FLK YE G
Sbjct: 91 DTGNDPAVFTKQNIDNFRRQI----QALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKG 146
Query: 116 HLVKKVTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAI 175
+ D + CP G L E +I+ +
Sbjct: 147 ----------------LAYVDEVPVNWCP-------------ALGTVLANEEVIDGKSER 177
Query: 176 CGRPISFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWI 220
G P+ R + +K+ +A+RL +E+ W ++K+M +WI
Sbjct: 178 GGHPVERRLMKQWMLKINAYADRLLEDLEELDWPESIKDMQRNWI 222
>pir||F71453 methionine--tRNA ligase truncated homolog PH0285 [imported] -
Pyrococcus horikoshii >gi|3256674|dbj|BAA29357.1|
(AP000001) 112aa long hypothetical methionyl-tRNA
synthetase [Pyrococcus horikoshii]
Length = 112
Score = 72.2 bits (174), Expect = 2e-11
Identities = 39/102 (38%), Positives = 60/102 (58%), Gaps = 1/102 (0%)
Query: 621 DDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYVVVV 680
D+F K ++VG + + + KL + VD G+E RT+V G+ PEEL + + V
Sbjct: 10 DEFWKFQMKVGLVKKAEKIKRTKKLIKLIVDFGNEERTIVTGIADQIPPEELEGKKFIFV 69
Query: 681 ANLEPKKLRGIGSQGMLLAADDGERVALLMP-DKEVKLGAKV 721
NL+PKK G+ SQGML+ A+ + L+P +EV +GA+V
Sbjct: 70 VNLKPKKFSGVESQGMLILAETEDGKVYLIPVPEEVPVGARV 111
>emb|CAB90791.1| (AL355652) putative Cofactor for methionyl-and glutamyl-tRNA
synthetases and G4 quadruplex nucleic acid binding
protein by similarity to yeast G4P1 [Schizosaccharomyces
pombe]
Length = 450
Score = 71.8 bits (173), Expect = 3e-11
Identities = 44/124 (35%), Positives = 68/124 (54%), Gaps = 10/124 (8%)
Query: 608 KEKKEGKEMYVKFDDFAK------LDLRVGKIIEVKDHPNADKLYVVKVDLGDEV--RTL 659
K+KK+ KE K A +D R+G I + HPNAD LYV + GD RT+
Sbjct: 258 KDKKDKKEKAPKEPPKAATPVPSMIDFRIGFIEKAVKHPNADSLYVSTIHCGDAEGPRTV 317
Query: 660 VAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGER--VALLMPDKEVKL 717
+GL KY E++ R V+VVANL+P +R + SQ M+ A ++ V ++P + ++
Sbjct: 318 CSGLVKYIPLEQMQQRKVIVVANLKPVNMRSVKSQAMVFCASSPDKSVVEFVLPPENAEI 377
Query: 718 GAKV 721
G ++
Sbjct: 378 GDRL 381
>dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halodurans]
Length = 806
Score = 70.2 bits (169), Expect = 8e-11
Identities = 58/228 (25%), Positives = 94/228 (40%), Gaps = 35/228 (15%)
Query: 3 RYMVTSALPYANGP-IHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL 61
++ PY +G +H GH G Y DI R R++G +V+ G D G P A+
Sbjct: 32 KFYALDMFPYPSGAGLHVGHPEG-YTATDILSRMKRMQGYNVLHPMGWDAFGLPAEQYAI 90
Query: 62 KEGRSPREIVDEFHEQIKITFQRAKISFDFFG--RTELPIHYKLSQEFFLKAYENGHLVK 119
G SP E ++ + + S+D+ T P +YK +Q F++ Y G
Sbjct: 91 DTGNSPAEFTEKNINTFRRQIKSLGFSYDWDREVNTTDPDYYKWTQWIFIQLYNKG---- 146
Query: 120 KVTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRP 179
AY D + CP G L E +I+ + G P
Sbjct: 147 ----LAYI--------DEVAVNWCP-------------ALGTVLANEEVIDGKSERGGHP 181
Query: 180 ISFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWI--EEGLE 225
+ R + +K+ ++A+RL +E+ W ++K+M +WI EG E
Sbjct: 182 VERRPMKQWMLKITEYADRLLEDLEELDWPESIKDMQRNWIGRSEGAE 229
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.322 0.142 0.433
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 286262086
Number of Sequences: 2977
Number of extensions: 13370488
Number of successful extensions: 32963
Number of sequences better than 1.0e-10: 106
Number of HSP's better than 0.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 32395
Number of HSP's gapped (non-prelim): 161
length of query: 722
length of database: 189,106,746
effective HSP length: 54
effective length of query: 668
effective length of database: 156,788,448
effective search space: 104734683264
effective search space used: 104734683264
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 168 (69.9 bits)