BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2385 (RAD3) DE:DNA REPAIR HELICASE RAD3
(637 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75044 DNA repair helicase rad3 PAB2385 - Pyrococcus abyssi... 1270 0.0
pir||B71116 probable helicase protein PH0697 - Pyrococcus horiko... 1071 0.0
emb|CAC11205.1| (AL445063) DNA repair helicase Rad3 related prot... 235 9e-61
gi|6321019 DNA repair helicase component of transcription factor... 167 4e-40
pir||S22660 excision repair protein rad15 [validated] - fission ... 159 9e-38
sp|P26659|RA15_SCHPO DNA REPAIR HELICASE RAD15 (RHP3) >gi|749046... 159 9e-38
emb|CAA43022.1| (X60499) rad15 [Schizosaccharomyces pombe] 159 1e-37
gb|AAF14582.1|AF188623_1 (AF188623) nucleotide excision repair p... 152 1e-35
pir||T49560 probable excision repair protein rhp3 [imported] - N... 152 2e-35
pir||I51720 probable DNA helicase ERCC2/XPD - southern platyfish... 149 8e-35
gi|6679681 excision repair 2 [Mus musculus] >gi|2495146|sp|O0881... 148 1e-34
sp|Q60452|XPD_CRIGR DNA-REPAIR PROTEIN COMPLEMENTING XP-D CELLS ... 148 1e-34
pir||T38730 probable helicase - fission yeast (Schizosaccharomyc... 148 1e-34
sp|P18074|XPD_HUMAN DNA-REPAIR PROTEIN COMPLEMENTING XP-D CELLS ... 146 5e-34
emb|CAA36463.1| (X52221) ercc2 gene product [Homo sapiens] 146 5e-34
pir||A72723 hypothetical protein APE0322 - Aeropyrum pernix (str... 137 4e-31
gb|AAD33587.1|AF132140_1 (AF132140) excision repair protein ERCC... 136 7e-31
pir||T21356 hypothetical protein F25H2.13 - Caenorhabditis elega... 132 1e-29
gb|AAF09041.1|AC011717_8 (AC011717) hypothetical protein; 30600-... 123 7e-27
gb|AAD55463.1|AC009322_3 (AC009322) Hypothetical protein [Arabid... 111 2e-23
gb|AAK40649.1| DNA helicase [Sulfolobus solfataricus] 109 9e-23
pir||T23694 hypothetical protein M03C11.2 - Caenorhabditis elega... 104 2e-21
gb|AAB62733.1| (U77066) RepD [Dictyostelium discoideum] 101 2e-20
pir||E83413 hypothetical protein PA1866 [imported] - Pseudomonas... 96 1e-18
gi|6325249 kinetochore protein in the DEAH box family; Chl1p [Sa... 95 2e-18
emb|CAA22963.1| (AL035331) /prediction=(method:""genefinder"", v... 93 8e-18
gb|AAC72116.1| (AC005278) Strong similarity to gb|U04968 nucleot... 90 5e-17
pir||T45294 hypothetical protein KIAA1088 [imported] - human (fr... 80 1e-13
gi|7706541 helicase-like protein NHL [Homo sapiens] >gi|11420403... 80 1e-13
gb|AAF35243.1| (AF217796) helicase-like protein NHL [Homo sapiens] 80 1e-13
gb|AAF59650.1| (AC024801) contains similarity to TR:Q91941 [Caen... 80 1e-13
emb|CAC16224.1| (AL353715) bK3184A7.3.2 (KIAA1088) [Homo sapiens] 80 1e-13
gb|AAF46074.1| (AE003435) CG4078 gene product [Drosophila melano... 80 1e-13
pir||T21711 hypothetical protein F33H2.1 - Caenorhabditis elegan... 75 3e-12
>pir||E75044 DNA repair helicase rad3 PAB2385 - Pyrococcus abyssi (strain Orsay)
>gi|5458763|emb|CAB50250.1| (AJ248287) DNA REPAIR
HELICASE RAD3 [Pyrococcus abyssi]
Length = 637
Score = 1270 bits (3251), Expect = 0.0
Identities = 637/637 (100%), Positives = 637/637 (100%)
Query: 1 MFEYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGYKV 60
MFEYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGYKV
Sbjct: 1 MFEYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGYKV 60
Query: 61 IYLARTHKQMDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSL 120
IYLARTHKQMDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSL
Sbjct: 61 IYLARTHKQMDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSL 120
Query: 121 KRLGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLELCPYEVTRKVGEKANV 180
KRLGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLELCPYEVTRKVGEKANV
Sbjct: 121 KRLGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLELCPYEVTRKVGEKANV 180
Query: 181 IVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIK 240
IVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIK
Sbjct: 181 IVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIK 240
Query: 241 EANEYGEKDIENFLSIFLRGLEIIYKEKLENYEISEVPLSPASIFEHVSSILGLRERDLL 300
EANEYGEKDIENFLSIFLRGLEIIYKEKLENYEISEVPLSPASIFEHVSSILGLRERDLL
Sbjct: 241 EANEYGEKDIENFLSIFLRGLEIIYKEKLENYEISEVPLSPASIFEHVSSILGLRERDLL 300
Query: 301 RFLQEMVEVGDAIREDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALE 360
RFLQEMVEVGDAIREDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALE
Sbjct: 301 RFLQEMVEVGDAIREDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALE 360
Query: 361 IVALDPSVALEFLEDVHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVLVAR 420
IVALDPSVALEFLEDVHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVLVAR
Sbjct: 361 IVALDPSVALEFLEDVHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVLVAR 420
Query: 421 DVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGK 480
DVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGK
Sbjct: 421 DVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGK 480
Query: 481 KVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIP 540
KVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIP
Sbjct: 481 KVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIP 540
Query: 541 YARPTPRVQAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDYRV 600
YARPTPRVQAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDYRV
Sbjct: 541 YARPTPRVQAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDYRV 600
Query: 601 LWNTVKRDLPDWMVETMQPVTLPLMRIKLRKFWRAVK 637
LWNTVKRDLPDWMVETMQPVTLPLMRIKLRKFWRAVK
Sbjct: 601 LWNTVKRDLPDWMVETMQPVTLPLMRIKLRKFWRAVK 637
>pir||B71116 probable helicase protein PH0697 - Pyrococcus horikoshii
>gi|3257105|dbj|BAA29788.1| (AP000003) 641aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 641
Score = 1071 bits (2739), Expect = 0.0
Identities = 517/632 (81%), Positives = 581/632 (91%)
Query: 3 EYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGYKVIY 62
+YFPY+ RP+Q EFIE+V++ VKRGE +I+EAPTGFGKTISVLAGVLP+AIS GYKV+Y
Sbjct: 5 QYFPYEKFRPNQREFIEIVKEAVKRGENLIVEAPTGFGKTISVLAGVLPYAISLGYKVVY 64
Query: 63 LARTHKQMDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSLKR 122
LARTHKQMDRVIEEL++I E ++VSGIEFRSRKDLCLH+YI+TFAQDAYTSMIVCKSL++
Sbjct: 65 LARTHKQMDRVIEELRKIGEKSEVSGIEFRSRKDLCLHAYIQTFAQDAYTSMIVCKSLRK 124
Query: 123 LGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLELCPYEVTRKVGEKANVIV 182
LGKCKY+ENLKEKRD+V EIV+FFL P +P EVIEYS LLELCPYE+T+KVGEKANV+V
Sbjct: 125 LGKCKYYENLKEKRDRVDEIVKFFLSFPPFPREVIEYSELLELCPYEITKKVGEKANVVV 184
Query: 183 ASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIKEA 242
ASYLYM++P IRQAFL+ LG++YSDLIVIFDEAHNLPDQAISALSDRLS+RS+ERAIKEA
Sbjct: 185 ASYLYMISPPIRQAFLENLGVDYSDLIVIFDEAHNLPDQAISALSDRLSVRSIERAIKEA 244
Query: 243 NEYGEKDIENFLSIFLRGLEIIYKEKLENYEISEVPLSPASIFEHVSSILGLRERDLLRF 302
EYGEKDIENFLSI LRGLEI+YKEKLENYE E+P+ P +F H +SILG R RD+
Sbjct: 245 EEYGEKDIENFLSILLRGLEILYKEKLENYESEEIPIRPEEVFLHPASILGWRGRDIGMM 304
Query: 303 LQEMVEVGDAIREDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALEIV 362
L++M+EVGDAIRED+IERNLPPRSYVGRVGEFLWNW+SL DR DYLH+FT+EKGLALE+V
Sbjct: 305 LEDMIEVGDAIREDRIERNLPPRSYVGRVGEFLWNWLSLRDREDYLHLFTKEKGLALELV 364
Query: 363 ALDPSVALEFLEDVHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVLVARDV 422
ALDPSVAL+FLE+VHSAI MSGTLSPLEAFRDIIGVNARLKKFPR+VK ENAIVLVARDV
Sbjct: 365 ALDPSVALDFLEEVHSAIFMSGTLSPLEAFRDIIGVNARLKKFPRIVKRENAIVLVARDV 424
Query: 423 STRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGKKV 482
STRG ERSP LYK++AEYIFEAVK PKNVGVFTASYEVLEG++STNVHI+IEEE+GKKV
Sbjct: 425 STRGIERSPPLYKRIAEYIFEAVKNTPKNVGVFTASYEVLEGVLSTNVHIKIEEEVGKKV 484
Query: 483 FIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYA 542
FIEK+DA S END ++ EFK E+KG G VLFGVMGGRNSEGQDYSGDEMNGVILVGIPYA
Sbjct: 485 FIEKKDAPSRENDEMIREFKEESKGKGAVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYA 544
Query: 543 RPTPRVQAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDYRVLW 602
RPTPRVQAQ RY+EKKFPGKGRYYGY+LPAHRKLAQAAGRVHRSE EKGSIVILDYRVLW
Sbjct: 545 RPTPRVQAQTRYFEKKFPGKGRYYGYILPAHRKLAQAAGRVHRSENEKGSIVILDYRVLW 604
Query: 603 NTVKRDLPDWMVETMQPVTLPLMRIKLRKFWR 634
VK+DLPDWMVETM PVTLP +RIKLR+FWR
Sbjct: 605 KNVKKDLPDWMVETMIPVTLPTLRIKLRRFWR 636
>emb|CAC11205.1| (AL445063) DNA repair helicase Rad3 related protein [Thermoplasma
acidophilum]
Length = 602
Score = 235 bits (594), Expect = 9e-61
Identities = 173/605 (28%), Positives = 292/605 (47%), Gaps = 40/605 (6%)
Query: 31 VIIEAPTGFGKTISVLAGVLPHAISFGYKVIYLARTHKQMDRVIEELKRIREIAKVSGIE 90
V +E+PTG GKTI L L ++ KV+YL RT+ Q ++VI+EL+ + K+ I
Sbjct: 7 VALESPTGSGKTIMALKSALQYSSERKLKVLYLVRTNSQEEQVIKELRSLSSTMKIRAIP 66
Query: 91 FRSRKDLC-LHSYIRTFAQ-DAYTSMIVCKSLKRL------GKCKYFENLKEKRDKVKEI 142
+ R ++C L+ + + +A + C KR C YF N K + D+ K
Sbjct: 67 MQGRVNMCILYRMVDDLHEINAESLAKFCNMKKREVMAGNEAACPYF-NFKIRSDETKRF 125
Query: 143 VEFFLENPSYPWEVIEYSNLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLG 202
+ F E P+ E +Y +CPYE + A++++A Y Y +N + + FL G
Sbjct: 126 L--FDELPTAE-EFYDYGERNNVCPYESMKAALPDADIVIAPYAYFLNRSVAEKFLSHWG 182
Query: 203 LEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIKEANEYGEKD------IENFLSI 256
+ + +++I DEAHNLPD S S R+S+ S+ RA +EA YG+ + + + + +
Sbjct: 183 VSRNQIVIILDEAHNLPDIGRSIGSFRISVESLNRADREAQAYGDPELSQKIHVSDLIEM 242
Query: 257 FLRGLEIIYKEKLENYEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVEVGDAIRED 316
L+ + E+ +V + E++ + ER++ L + G+ + +
Sbjct: 243 IRSALQSMVSERCGK---GDVRIRFQEFMEYMRIMNKRSEREIRSLLNYLYLFGEYVENE 299
Query: 317 KIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALEIVALDPSVALEFLEDV 376
K + P SY V + + S D Y + + E G ++ LDPS LE L++
Sbjct: 300 KEKVGKVPFSYCSSVASRIIAF-SDQDEEKYAAILSPEDGGYMQAACLDPSGILEVLKE- 357
Query: 377 HSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVLVARDVSTRGEERSPVLYKK 436
I MSGTL P + + DI G KK + EN + VS++ + +
Sbjct: 358 SKTIHMSGTLDPFDFYSDITGFEIPFKKIGEIFPPENRYIAYYDGVSSKYDTLDEKELDR 417
Query: 437 LAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGKKVFIEKRDASSSENDA 496
+A I + + + KN V+ SY +++ R+E + + E R E +
Sbjct: 418 MATVIEDIILKVKKNTIVYFPSYSLMD---------RVENRVSFEHMKEYRGIDQKELYS 468
Query: 497 LVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRVQAQIRYYE 556
++ +F+ + G +F V GGR SEG ++ G+E+ +IL G+P+ RP ++ YYE
Sbjct: 469 MLKKFRRD----HGTIFAVSGGRLSEGINFPGNELEMIILAGLPFPRPDAINRSLFDYYE 524
Query: 557 KKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVET 616
+K+ GKG Y + P K+ Q GR+ RS E+ G+ VILD R ++ +PD M +T
Sbjct: 525 RKY-GKGWEYSVVYPTAIKIRQEIGRLIRSAEDTGACVILDKRA--GQFRKFIPD-MKKT 580
Query: 617 MQPVT 621
P +
Sbjct: 581 SDPAS 585
>gi|6321019 DNA repair helicase component of transcription factor b; Rad3p
[Saccharomyces cerevisiae]
>gi|131812|sp|P06839|RAD3_YEAST DNA REPAIR HELICASE RAD3
>gi|83445|pir||A23308 transcription initiation factor b
85K chain RAD3 - yeast (Saccharomyces cerevisiae)
>gi|4269|emb|CAA26215.1| (X02368) RAD3 protein
[Saccharomyces cerevisiae] >gi|172331|gb|AAA34943.1|
(K03293) RAD3 protein [Saccharomyces cerevisiae]
>gi|603412|gb|AAB64698.1| (U18922) Rad3p: DNA repair
helicase component of transcription factor b
[Saccharomyces cerevisiae]
Length = 778
Score = 167 bits (418), Expect = 4e-40
Identities = 179/718 (24%), Positives = 321/718 (43%), Gaps = 119/718 (16%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGY--KVIY 62
FPY + P Q ++ ++ + G I+E P+G GKT+S+L+ + + + + K+IY
Sbjct: 12 FPYPKIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQMHYPEHRKIIY 71
Query: 63 LARTHKQMDRVIEELK-----RIREIA---KVSGIEFRSRKDLCLHSYIR-----TFAQD 109
+RT ++++ + EL+ R +E+ G+ SRK+LCLH + T +
Sbjct: 72 CSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEVSKERKGTVVDE 131
Query: 110 AYTSMIVCKSLKRLGK--------CKYFENLKEKRDKVKEIVEFFLENPSYPWE-VIEYS 160
M ++ ++L + C+Y ENL VE +L + +E +++Y
Sbjct: 132 KCRRMTNGQAKRKLEEDPEANVELCEYHENLYNIE------VEDYLPKGVFSFEKLLKYC 185
Query: 161 NLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPD 220
LCPY + R++ N+I+ SY Y+++P I + + + D IVIFDEAHN+ +
Sbjct: 186 EEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVS---KDSIVIFDEAHNIDN 242
Query: 221 QAISALSDRLSIRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLENYEIS----- 275
I +LS L+ ++ RA + AN E+ I + + L+ Y++ ++ +
Sbjct: 243 VCIESLSLDLTTDALRRATRGANALDER-ISEVRKVDSQKLQDEYEKLVQGLHSADILTD 301
Query: 276 ------EVPLSPASIF-----------EHVSSILGLRERDLLRFLQEMVEVGDAIREDK- 317
E P+ P + EH S L + L+ +L+ ++V I E
Sbjct: 302 QEEPFVETPVLPQDLLTEAIPGNIRRAEHFVSFL----KRLIEYLKTRMKVLHVISETPK 357
Query: 318 -----------IERNLPPRSYVGRVGEFLWNWISLADRSDYLH----------VFTREKG 356
IER P + L + + + D+ + T E+G
Sbjct: 358 SFLQHLKQLTFIERK--PLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEG 415
Query: 357 LALEI-----------------VALDPSVALE-FLEDVHSAILMSGTLSPLEAFRDIIGV 398
L I LD S+A++ E S I+ SGT+SPL+ + ++
Sbjct: 416 FLLIIEPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMYPRMLNF 475
Query: 399 NARLKKFPRMVKSENA----IVLVARD---VSTRGEERS-PVLYKKLAEYIFEAVKIIPK 450
L+K M ++ + I+ D +S+R E R+ P + + + E KI P
Sbjct: 476 KTVLQKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPD 535
Query: 451 NVGVFTASYEVLEGLISTNVHIRIEEEIGKK--VFIEKRDASSSENDALVAEFKAEAKGN 508
+ VF SY +E ++S + I +E+ K + +E DA + + AL KA + G
Sbjct: 536 GMVVFFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQET-SLALETYRKACSNGR 594
Query: 509 GGVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYG 567
G +L V G+ SEG D+ V+++GIP+ R+ +A++ + + + + R
Sbjct: 595 GAILLSVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENY--RIREND 652
Query: 568 YL-LPAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
+L A R AQ GRV R +++ G +V+ D R ++ + LP W+ + + L L
Sbjct: 653 FLSFDAMRHAAQCLGRVLRGKDDYGVMVLADRR--FSRKRSQLPKWIAQGLSDADLNL 708
>pir||S22660 excision repair protein rad15 [validated] - fission yeast
(Schizosaccharomyces pombe) >gi|5044|emb|CAA45870.1|
(X64583) rhp3+ [Schizosaccharomyces pombe]
Length = 772
Score = 159 bits (398), Expect = 9e-38
Identities = 173/697 (24%), Positives = 297/697 (41%), Gaps = 100/697 (14%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISF--GYKVIY 62
FPY + P Q +++ ++ + G ++E P+G GKTIS+L+ ++ + + K+IY
Sbjct: 12 FPYPRIYPEQYQYMCDLKHSLDAGGIALLEMPSGTGKTISLLSLIVSYQQHYPEHRKLIY 71
Query: 63 LARTHKQMDRVIEELKRIREIAKVS--------GIEFRSRKDLCLHSYIRTFAQDAYTSM 114
+RT ++D+ + ELKR+ G+ SRK+LCLH +R ++
Sbjct: 72 CSRTMSEIDKALAELKRLMAYRTSQLGYEEPFLGLGLTSRKNLCLHPSVRR-EKNGNVVD 130
Query: 115 IVCKSL-------KRLG-----KCKYFENLKEKRDKVKEIVEFFLENPSYPW-EVIEYSN 161
C+SL +RL C++ +NL++ + N + ++ EY
Sbjct: 131 ARCRSLTAGFVREQRLAGMDVPTCEFHDNLEDLEP------HSLISNGVWTLDDITEYGE 184
Query: 162 LLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQ 221
CPY R++ NVI+ SY Y+++P I + L D IV+FDEAHN+ +
Sbjct: 185 KTTRCPYFTVRRMLPFCNVIIYSYHYLLDPKIAERVSRELN---KDCIVVFDEAHNIDNV 241
Query: 222 AISALSDRL----------SIRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLEN 271
I +LS L SI S+E+ + E + K +++ +RGL+ E+
Sbjct: 242 CIESLSIDLTESSLRKASKSILSLEQKVNEVKQSDSKKLQDEYQKLVRGLQDANAANDED 301
Query: 272 YEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVEVGDAIREDKIERNLPPRSYVGRV 331
++ P+ P + + R + FL+ VE + P S++ V
Sbjct: 302 QFMAN-PVLPEDVLKEAVPGNIRRAEHFIAFLKRFVEYLKTRMKVLHVIAETPTSFLQHV 360
Query: 332 GEFLW-------------------NWISLADRSDYLH--------VFTREKGLAL----- 359
+ + ISL + L V T E+G L
Sbjct: 361 KDITFIDKKPLRFCAERLTSLVRALQISLVEDFHSLQQVVAFATLVATYERGFILILEPF 420
Query: 360 ------------EIVALDPSVALE-FLEDVHSAILMSGTLSPLEAFRDIIGVNARLKKFP 406
LD S+A++ E S I+ SGTLSPL+ + ++ N +++
Sbjct: 421 ETENATVPNPILRFSCLDASIAIKPVFERFRSVIITSGTLSPLDMYPKMLQFNTVMQESY 480
Query: 407 RMVKSENAI--VLVARD-----VSTRGEERS-PVLYKKLAEYIFEAVKIIPKNVGVFTAS 458
M + N ++V R +S++ E R+ P + + + E KI P + F S
Sbjct: 481 GMSLARNCFLPMVVTRGSDQVAISSKFEARNDPSVVRNYGNILVEFSKITPDGLVAFFPS 540
Query: 459 YEVLEGLISTNVHIRIEEEIGKKVFIEKRDASSSENDALVAEFKAE-AKGNGGVLFGVMG 517
Y LE ++S+ + I +E+ K I E + ++A + G G VL V
Sbjct: 541 YLYLESIVSSWQSMGILDEVWKYKLILVETPDPHETTLALETYRAACSNGRGAVLLSVAR 600
Query: 518 GRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAHRKL 576
G+ SEG D+ VI+ GIPY RV +A++ + + + + A R
Sbjct: 601 GKVSEGVDFDHHYGRAVIMFGIPYQYTESRVLKARLEFLRDTYQIREADF-LTFDAMRHA 659
Query: 577 AQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWM 613
AQ GRV R +++ G +V+ D R + + LP W+
Sbjct: 660 AQCLGRVLRGKDDHGIMVLADKRYGRSDKRTKLPKWI 696
>sp|P26659|RA15_SCHPO DNA REPAIR HELICASE RAD15 (RHP3) >gi|7490468|pir||T38053 dna repair
helicase rad15 - fission yeast (Schizosaccharomyces
pombe) >gi|1177345|emb|CAA93221.1| (Z69239) dna repair
helicase rad15 [Schizosaccharomyces pombe]
Length = 772
Score = 159 bits (398), Expect = 9e-38
Identities = 173/697 (24%), Positives = 297/697 (41%), Gaps = 100/697 (14%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISF--GYKVIY 62
FPY + P Q +++ ++ + G ++E P+G GKTIS+L+ ++ + + K+IY
Sbjct: 12 FPYPRIYPEQYQYMCDLKHSLDAGGIALLEMPSGTGKTISLLSLIVSYQQHYPEHRKLIY 71
Query: 63 LARTHKQMDRVIEELKRIREIAKVS--------GIEFRSRKDLCLHSYIRTFAQDAYTSM 114
+RT ++D+ + ELKR+ G+ SRK+LCLH +R ++
Sbjct: 72 CSRTMSEIDKALAELKRLMAYRTSQLGYEEPFLGLGLTSRKNLCLHPSVRR-EKNGNVVD 130
Query: 115 IVCKSL-------KRLG-----KCKYFENLKEKRDKVKEIVEFFLENPSYPW-EVIEYSN 161
C+SL +RL C++ +NL++ + N + ++ EY
Sbjct: 131 ARCRSLTAGFVREQRLAGMDVPTCEFHDNLEDLEP------HSLISNGVWTLDDITEYGE 184
Query: 162 LLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQ 221
CPY R++ NVI+ SY Y+++P I + L D IV+FDEAHN+ +
Sbjct: 185 KTTRCPYFTVRRMLPFCNVIIYSYHYLLDPKIAERVSRELS---KDCIVVFDEAHNIDNV 241
Query: 222 AISALSDRL----------SIRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLEN 271
I +LS L SI S+E+ + E + K +++ +RGL+ E+
Sbjct: 242 CIESLSIDLTESSLRKASKSILSLEQKVNEVKQSDSKKLQDEYQKLVRGLQDANAANDED 301
Query: 272 YEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVEVGDAIREDKIERNLPPRSYVGRV 331
++ P+ P + + R + FL+ VE + P S++ V
Sbjct: 302 QFMAN-PVLPEDVLKEAVPGNIRRAEHFIAFLKRFVEYLKTRMKVLHVIAETPTSFLQHV 360
Query: 332 GEFLW-------------------NWISLADRSDYLH--------VFTREKGLAL----- 359
+ + ISL + L V T E+G L
Sbjct: 361 KDITFIDKKPLRFCAERLTSLVRALQISLVEDFHSLQQVVAFATLVATYERGFILILEPF 420
Query: 360 ------------EIVALDPSVALE-FLEDVHSAILMSGTLSPLEAFRDIIGVNARLKKFP 406
LD S+A++ E S I+ SGTLSPL+ + ++ N +++
Sbjct: 421 ETENATVPNPILRFSCLDASIAIKPVFERFRSVIITSGTLSPLDMYPKMLQFNTVMQESY 480
Query: 407 RMVKSENAI--VLVARD-----VSTRGEERS-PVLYKKLAEYIFEAVKIIPKNVGVFTAS 458
M + N ++V R +S++ E R+ P + + + E KI P + F S
Sbjct: 481 GMSLARNCFLPMVVTRGSDQVAISSKFEARNDPSVVRNYGNILVEFSKITPDGLVAFFPS 540
Query: 459 YEVLEGLISTNVHIRIEEEIGKKVFIEKRDASSSENDALVAEFKAE-AKGNGGVLFGVMG 517
Y LE ++S+ + I +E+ K I E + ++A + G G VL V
Sbjct: 541 YLYLESIVSSWQSMGILDEVWKYKLILVETPDPHETTLALETYRAACSNGRGAVLLSVAR 600
Query: 518 GRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAHRKL 576
G+ SEG D+ VI+ GIPY RV +A++ + + + + A R
Sbjct: 601 GKVSEGVDFDHHYGRAVIMFGIPYQYTESRVLKARLEFLRDTYQIREADF-LTFDAMRHA 659
Query: 577 AQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWM 613
AQ GRV R +++ G +V+ D R + + LP W+
Sbjct: 660 AQCLGRVLRGKDDHGIMVLADKRYGRSDKRTKLPKWI 696
>emb|CAA43022.1| (X60499) rad15 [Schizosaccharomyces pombe]
Length = 772
Score = 159 bits (397), Expect = 1e-37
Identities = 173/697 (24%), Positives = 296/697 (41%), Gaps = 100/697 (14%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISF--GYKVIY 62
FPY + P Q +++ ++ + G ++E P+G GKTIS+L+ ++ + + K+IY
Sbjct: 12 FPYPRIYPEQYQYMCDLKHSLDAGGIALLEMPSGTGKTISLLSLIVSYQQHYPEHRKLIY 71
Query: 63 LARTHKQMDRVIEELKRIREIAKVS--------GIEFRSRKDLCLHSYIRTFAQDAYTSM 114
+RT ++D+ + ELKR+ G+ SRK+LCLH +R ++
Sbjct: 72 CSRTMSEIDKALAELKRLMAYRTSQLGYEEPFLGLGLTSRKNLCLHPSVRR-EKNGNVVD 130
Query: 115 IVCKSL-------KRLG-----KCKYFENLKEKRDKVKEIVEFFLENPSYPW-EVIEYSN 161
C+SL +RL C++ +NL++ + N + ++ EY
Sbjct: 131 ARCRSLTAGFVREQRLAGMDVPTCEFHDNLEDLEP------HSLISNGVWTLDDITEYGE 184
Query: 162 LLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQ 221
CPY R++ NVI+ SY Y+++P I + L D IV+FDEAHN+ +
Sbjct: 185 KTTRCPYFTVRRMLPFCNVIIYSYHYLLDPKIAERVSRELS---KDCIVVFDEAHNIDNV 241
Query: 222 AISALSDRL----------SIRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLEN 271
I +LS L SI S+E+ + E + K +++ +RGL+ E+
Sbjct: 242 CIESLSIDLTESSLRKASKSILSLEQKVNEVKQSDSKKLQDEYQKLVRGLQDANAANDED 301
Query: 272 YEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVEVGDAIREDKIERNLPPRSYVGRV 331
++ P+ P + + R + FL+ VE + P S++ V
Sbjct: 302 QFMAN-PVLPEDVLKEAVPGNIRRAEHFIAFLKRFVEYLKTRMKVLHVIAETPTSFLQHV 360
Query: 332 GEFLW-------------------NWISLADRSDYLH--------VFTREKGLAL----- 359
+ + ISL + L V T E+G L
Sbjct: 361 KDITFIDKKPLRFCAERLTSLVRALQISLVEDFHSLQQVVAFATLVATYERGFILILEPF 420
Query: 360 ------------EIVALDPSVALE-FLEDVHSAILMSGTLSPLEAFRDIIGVNARLKKFP 406
LD S+A++ E S I+ SGTLSPL+ + ++ N +++
Sbjct: 421 ETENATVPNPILRFSCLDASIAIKPVFERFRSVIITSGTLSPLDMYPKMLQFNTVMQESY 480
Query: 407 RMVKSENAI--VLVARD-----VSTRGEERS-PVLYKKLAEYIFEAVKIIPKNVGVFTAS 458
M + N ++V R +S++ E R+ P + + + E KI P + F S
Sbjct: 481 GMSLARNCFLPMVVTRGSDQVAISSKFEARNDPSVVRNYGNILVEFSKITPDGLVAFFPS 540
Query: 459 YEVLEGLISTNVHIRIEEEIGKKVFIEKRDASSSENDALVAEFKAE-AKGNGGVLFGVMG 517
Y LE ++S+ + I +E+ K I E + ++A G G VL V
Sbjct: 541 YLYLESIVSSWQSMGILDEVWKYKLILVETPDPHETTLALETYRAACTNGRGAVLLSVAR 600
Query: 518 GRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAHRKL 576
G+ SEG D+ VI+ GIPY RV +A++ + + + + A R
Sbjct: 601 GKVSEGVDFDHHYGRAVIMFGIPYQYTESRVLKARLEFLRDTYQIREADF-LTFDAMRHA 659
Query: 577 AQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWM 613
AQ GRV R +++ G +V+ D R + + LP W+
Sbjct: 660 AQCLGRVLRGKDDHGIMVLADKRYGRSDKRTKLPKWI 696
>gb|AAF14582.1|AF188623_1 (AF188623) nucleotide excision repair protein XP-D homolog
[Arabidopsis thaliana]
Length = 758
Score = 152 bits (380), Expect = 1e-35
Identities = 176/712 (24%), Positives = 314/712 (43%), Gaps = 105/712 (14%)
Query: 4 YFPYKTLRPHQDEF-IELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAIS---FGYK 59
YFPY + P Q E+ +EL R + +G ++E PTG GKTI++L+ + + +S K
Sbjct: 11 YFPYDNIYPEQYEYMVELKRALDAKGH-CLLEMPTGTGKTIALLSLITSYRLSRPDSPIK 69
Query: 60 VIYLARTHKQMDRVIEELKRIREI--------AKVSGIEFRSRKDLCLHSYIRTFAQDAY 111
++Y RT +M++ + ELK + + AK+ + SRK+LC+++ + A++
Sbjct: 70 LVYCTRTVHEMEKTLGELKLLHDYQVRHLGTQAKILALGLSSRKNLCVNTKVLA-AENRD 128
Query: 112 TSMIVCKSLKRLGKCKYFENLKEKRDKVKEIVEFF------LENPSYPWEVIEYSNLLEL 165
+ C R + L + V E+ +FF EN P V +L
Sbjct: 129 SVDAAC----RKRTASWVRALSTENPNV-ELCDFFENYEKAAENALLPPGVYTLEDLRAF 183
Query: 166 ------CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLP 219
CPY + R + + ANVIV SY Y+++P + L + +V+FDEAHN+
Sbjct: 184 GKNRGWCPYFLARHMIQFANVIVYSYQYLLDPKVAGFISKEL---QKESVVVFDEAHNID 240
Query: 220 DQAISALSDRLSIRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLENYEIS---- 275
+ I ALS + ++E A + N+ ++I+ F + L Y +E +
Sbjct: 241 NVCIEALSVSVRRVTLEGANRNLNKI-RQEIDRFKATDAGRLRAEYNRLVEGLALRGDLS 299
Query: 276 ------EVPLSPASIFEHVSSILGLRERDLLRFLQEMVE-VGDAIREDKIERNLPPRSYV 328
P P I + R + L+ +++ +G + + +E+ P S+V
Sbjct: 300 GGDQWLANPALPHDILKEAVPGNIRRAEHFVHVLRRLLQYLGVRLDTENVEKE-SPVSFV 358
Query: 329 GRVG-----------------EFLWNWISLADRSDYLH----------VFTREKGLA--- 358
+ + L + + D ++L V T +G +
Sbjct: 359 SSLNSQAGIEQKTLKFCYDRLQSLMLTLEITDTDEFLPIQTVCDFATLVGTYARGFSIII 418
Query: 359 --------------LEIVALDPSVALEFLED-VHSAILMSGTLSPLEAFRDIIGVNARLK 403
L++ D S+A++ + D S ++ SGTLSP++ + ++ +
Sbjct: 419 EPYDERMPHIPDPILQLSCHDASLAIKPVFDRFQSVVITSGTLSPIDLYPRLLNFTPVVS 478
Query: 404 KFPRMVKSENAI--VLVAR-----DVSTRGEERS-PVLYKKLAEYIFEAVKIIPKNVGVF 455
+ +M + + I +++ R VST+ + RS P + + + + E V I+P V F
Sbjct: 479 RSFKMSMTRDCICPMVLTRGSDQLPVSTKFDMRSDPGVVRNYGKLLVEMVSIVPDGVVCF 538
Query: 456 TASYEVLEGLISTNVHIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNGGVLF 513
SY ++G+I+T I EEI K VFIE +D + AL +A G G V F
Sbjct: 539 FVSYSYMDGIIATWNETGILEEIMQQKLVFIETQDVVET-TLALDNYRRACDCGRGAVFF 597
Query: 514 GVMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPA 572
V G+ +EG D+ V++ G+P+ ++ +A++ Y F K + A
Sbjct: 598 SVARGKVAEGIDFDRHYGRLVVMYGVPFQYTLSKILRARLEYLHDTFQIKEGDF-LTFDA 656
Query: 573 HRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
R+ AQ GRV RS+ + G ++ D R + + LP W++ ++ L L
Sbjct: 657 LRQAAQCVGRVIRSKADYGMMIFADKRYSRHDKRSKLPGWILSHLRDAHLNL 708
>pir||T49560 probable excision repair protein rhp3 [imported] - Neurospora
crassa >gi|7800963|emb|CAB91361.1| (AL355930) probable
excision repair protein rhp3 [Neurospora crassa]
Length = 821
Score = 152 bits (379), Expect = 2e-35
Identities = 167/709 (23%), Positives = 309/709 (43%), Gaps = 126/709 (17%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISF--GYKVIY 62
FPY + P Q ++ ++ + G ++E P+G GKT+++L+ ++ + + K+IY
Sbjct: 27 FPYPRIYPEQYAYMVDLKKTLDAGGNCVLEMPSGTGKTVTLLSLIVAYQQYYPEHRKLIY 86
Query: 63 LARTHKQMDRVIEELK--------RIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSM 114
+RT ++++ + EL+ R+ + G+ SRK+LCLH ++ A
Sbjct: 87 CSRTMSEIEKALVELRALMKFRAERLGHEEEFRGLGLTSRKNLCLHPSVKREKSGAIVD- 145
Query: 115 IVCKSL------------KRLGKCKYFENLKEKRDKVKEIVEFFLENPSYPWE---VIEY 159
C+SL + + C Y +NL +++E P+ W ++ Y
Sbjct: 146 ARCRSLTAGFVKEKREKGENVETCVYHDNL--------DLLEPHNLIPNGIWTLDGLMRY 197
Query: 160 SNLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLP 219
+ CPY R++ + NVI+ SY Y+++P I + L D IV+FDEAHN+
Sbjct: 198 GEEKKQCPYFTARRMMQHCNVIIYSYHYLLDPKIAERVSKDLS---KDCIVVFDEAHNID 254
Query: 220 DQAISALSDRLSIRSVERA----------IKEANEYGEKDIENFLSIFLRGLEIIYKEKL 269
+ I +LS ++ S+ RA I E + ++ +++ + GL+ + + +
Sbjct: 255 NVCIESLSTDITQDSLMRATRGAQNLEAKISEMKDSDQEKLQSEYEKLVEGLKGLDEGRQ 314
Query: 270 ENYEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVE-VGDAIREDKIERNLPPRSYV 328
E+ ++ L + E V + R + FL+ +E + ++ ++ PP S++
Sbjct: 315 EDAFMANPTLPDDLLKEAVPGNI-RRAEHFVAFLRRFIEYLKTRMKVRQVISETPP-SFL 372
Query: 329 GRVGEF-----------------LWNWISLADRSDY----------LHVFTREKGL---- 357
+ E+ L + L + DY V T EKG
Sbjct: 373 AHLKEYTFIEKKPLRFCAERLTSLVRTLELTNIEDYRPLQEVATFATLVATYEKGFLLIL 432
Query: 358 -------------ALEIVALDPSVALEFLED-VHSAILMSGTLSPLEAFRDIIGVNARLK 403
L LD ++A++ + D S I+ SGT+SPLE + ++
Sbjct: 433 EPYESDTAKTPNPVLHFTCLDAAIAIKPVFDRFSSVIITSGTISPLEMY-------PKML 485
Query: 404 KFPRMVKSENAIVLVARD----VSTRGEERS-----------PVLYKKLAEYIFEAVKII 448
F +V+ A+ L R + TRG +++ P + + + E +I
Sbjct: 486 NFETVVQESYAMTLARRSFLPMIVTRGSDQASISTSFQVRNEPSVVRNYGNLLTEFARIT 545
Query: 449 PKNVGVFTASYEVLEGLISTNVHIRIEEEIGKK--VFIEKRDASSSENDALVAEFKAEAK 506
P + VF SY +E +IS + I +E+ K + +E DA + + AL A
Sbjct: 546 PDGMVVFFPSYLYMESIISMWQGMGILDEVWKHKLILVETPDAQET-SLALETYRTACCN 604
Query: 507 GNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRY 565
G G +L V G+ SEG D+ V+ +G+P+ R+ +A++ + + + + R
Sbjct: 605 GRGAILLCVARGKVSEGIDFDHQYGRTVLCIGVPFQYTESRILKARLEFLRETY--RIRE 662
Query: 566 YGYL-LPAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWM 613
+L A R AQ GRV R +++ G +V+ D R + + LP W+
Sbjct: 663 NDFLSFDAMRHAAQCLGRVLRGKDDYGVMVLADRRFM--KKRAQLPKWI 709
>pir||I51720 probable DNA helicase ERCC2/XPD - southern platyfish
>gi|604371|gb|AAA85822.1| (U17896) ERCC2/XPD gene
product [Xiphophorus maculatus]
Length = 760
Score = 149 bits (373), Expect = 8e-35
Identities = 173/711 (24%), Positives = 302/711 (42%), Gaps = 103/711 (14%)
Query: 4 YFPYKTLRPHQDEF-IELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGY---K 59
YFPY + P Q + +EL R + +G V+ E P+G GKTIS+L+ ++ + +F K
Sbjct: 11 YFPYDYIYPEQYSYMLELKRTLDAKGHGVL-EMPSGTGKTISLLSLIVAYQRAFPLDVTK 69
Query: 60 VIYLARTHKQMDRVIEELKRIREI-AKVSG-------IEFRSRKDLCLHSYIRT--FAQD 109
+IY +RT ++++V+EEL+++ E AK +G + SRK+LC+H + + F ++
Sbjct: 70 LIYCSRTVPEIEKVVEELRKLMEFYAKETGEVNNFLALSLSSRKNLCIHPEVSSLRFGKE 129
Query: 110 AYTSMIVCKSLKRLG-KCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLEL--- 165
C SL + + N + + E + P + +L +
Sbjct: 130 VDGK---CHSLTASYIRAQRHSNPNQPVCRFYEEFDAVGRQVPLPAGIYNLDDLKDFGRR 186
Query: 166 ---CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQA 222
CPY + R AN++V SY Y+++P I L + +V+FDEAHN+ +
Sbjct: 187 KGWCPYYLARYSILHANIVVYSYHYLLDPKIADLVSKELAKKS---VVVFDEAHNIDNVC 243
Query: 223 ISALSDRLSIRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLENYEISEV----- 277
I ++S ++ R+V+R + + I L Y+ +E + + V
Sbjct: 244 IDSMSVNITRRTVDRCQNNVDTL-QNTIHKIKETDAAKLREEYRRLVEGLKEANVARETD 302
Query: 278 -----PLSPASIF-EHVSSILGLRE------RDLLRFLQEMVEVGDAIRE---------- 315
P+ P + E V + E R L +L+ + V ++E
Sbjct: 303 IYLANPVLPDEVLQEAVPGSIRTAEHFVGFLRRFLEYLKARLRVQHVVQESAPQFLKDIF 362
Query: 316 DKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVF----------TREKGLA------- 358
DK+ + P + + L + +AD +D+ V T +G
Sbjct: 363 DKVCIDRKPLRFCAERLQCLLRTLEIADIADFSAVTLISNFATLVSTYSQGFTIIIEPFE 422
Query: 359 ----------LEIVALDPSVALE-FLEDVHSAILMSGTLSPLEAFRDIIGVN-------- 399
L +DPS+A++ + S I+ SGTLSPL+ + I+
Sbjct: 423 DRTPTIANPVLHFSCMDPSIAIKPVFQRFQSVIITSGTLSPLDIYPRILDFRPVTMASFT 482
Query: 400 ---ARLKKFPRMVKSENAIVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFT 456
AR P +V N V ++ TR + + + + E ++P + F
Sbjct: 483 MTLARTCLCPLIVGRGNDQVALSSKFETREDF---AVIRNYGNLLLEMSAVVPDGIVAFF 539
Query: 457 ASYEVLEGLISTNVHIRIEEEIGKK--VFIEKRDASSSENDALVAEFKAEAKGNGGVLFG 514
SY +E ++++ I E I K +FIE +DA+ + AL +A G G +L
Sbjct: 540 TSYVYMENIVASWYEQGILENIQKNKLIFIETQDAAETSM-ALEKYQEACENGRGAILLS 598
Query: 515 VMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAH 573
V G+ SEG D+ VI+ G+PY R+ +A++ Y +F + + A
Sbjct: 599 VARGKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDF-LTFDAM 657
Query: 574 RKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
R AQ GR R + + G ++ D R + + LP W+ E + +L L
Sbjct: 658 RHAAQCLGRAIRGKTDYGLMIFADKRYARSDKRGKLPRWIQEHINDGSLNL 708
>gi|6679681 excision repair 2 [Mus musculus] >gi|2495146|sp|O08811|XPD_MOUSE
DNA-REPAIR PROTEIN COMPLEMENTING XP-D CELLS (XERODERMA
PIGMENTOSUM GROUP D COMPLEMENTING PROTEIN) (DNA EXCISION
REPAIR PROTEIN ERCC-2) >gi|2114484|gb|AAB58296.1|
(U97572) DNA helicase [Mus musculus]
Length = 760
Score = 148 bits (371), Expect = 1e-34
Identities = 184/716 (25%), Positives = 303/716 (41%), Gaps = 113/716 (15%)
Query: 4 YFPYKTLRPHQDEF-IELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGY---K 59
YFPY + P Q + +EL R + +G V+ E P+G GKT+S+LA ++ + ++ K
Sbjct: 11 YFPYDYIYPEQFSYMLELKRTLDAKGHGVL-EMPSGTGKTVSLLALIVAYQRAYPLEVTK 69
Query: 60 VIYLARTHKQMDRVIEELKRI--------REIAKVSGIEFRSRKDLCLHSYIR--TFAQD 109
+IY +RT ++++VIEEL+++ E G+ SRK+LC+H + F +D
Sbjct: 70 LIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKD 129
Query: 110 AYTSMIVCKSL-KRLGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLEL--- 165
C SL + +Y ++ + E + P + +L L
Sbjct: 130 VDGK---CHSLTASYVRAQYQQDASLPHCRFYEEFDIHGRQMPLPAGIYNLDDLKALGQR 186
Query: 166 ---CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQA 222
CPY + R ANV+V SY Y+++P I L + +V+FDEAHN+ +
Sbjct: 187 QGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARK---AVVVFDEAHNIDNVC 243
Query: 223 ISALSDRLSIRSVERA-------------IKEANEYGEKDIENFLSIFLRGLEIIYK--E 267
I ++S L+ R+++R IKE +E +D L LR + +
Sbjct: 244 IDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASVARETDA 303
Query: 268 KLENYEISEVPLS---PASI--FEHVSSILGLRERDLLRFLQEMVEVGDAIREDK----- 317
L N + + L P SI EH L R LL +++ + V ++E
Sbjct: 304 HLANPVLPDEVLQEAVPGSIRTAEHFLGFL----RRLLEYVKWRLRVQHVVQESPPAFLS 359
Query: 318 -------IERNLPPRSYVGRVGEFLWNWISLADRSDY----------LHVFTREKGL--- 357
I+R P R R+ L + + +AD +D+ V T KG
Sbjct: 360 GLAQRVCIQRK-PLRFCAERLRSLL-HTLEIADLADFSPLTLLANFATLVSTYAKGFTII 417
Query: 358 --------------ALEIVALDPSVALE-FLEDVHSAILMSGTLSPLEAFRDIIGVN--- 399
L +D S+A++ E S I+ SGTLSPL+ + I+ +
Sbjct: 418 IEPFDDRTPTIANPVLHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVT 477
Query: 400 --------ARLKKFPRMVKSENAIVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKN 451
AR+ P ++ N V ++ TR + + + E ++P
Sbjct: 478 MATFTMTLARVCLCPMIIGRGNDQVAISSKFETR---EDIAVIRNYGNLLLEMSAVVPDG 534
Query: 452 VGVFTASYEVLEGLISTNVHIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNG 509
+ F SY+ +E +++ I E I K +FIE +D + + + AL +A G G
Sbjct: 535 IVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAET-SVALEKYQEACENGRG 593
Query: 510 GVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGY 568
VL V G+ SEG D+ VI+ G+PY R+ +A++ Y +F + +
Sbjct: 594 AVLLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDF-L 652
Query: 569 LLPAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
A R AQ GR R + + G +V D R + LP W+ E + L L
Sbjct: 653 TFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNL 708
>sp|Q60452|XPD_CRIGR DNA-REPAIR PROTEIN COMPLEMENTING XP-D CELLS (XERODERMA PIGMENTOSUM
GROUP D COMPLEMENTING PROTEIN) (DNA EXCISION REPAIR
PROTEIN ERCC-2) >gi|1083179|pir||A55732 excision repair
protein ERCC2 - Chinese hamster
>gi|604908|gb|AAC13749.1| (U04968) nucleotide excision
repair protein [Cricetulus griseus]
Length = 760
Score = 148 bits (371), Expect = 1e-34
Identities = 175/711 (24%), Positives = 296/711 (41%), Gaps = 103/711 (14%)
Query: 4 YFPYKTLRPHQDEF-IELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGY---K 59
YFPY + P Q + +EL R + +G V+ E P+G GKT+S+LA ++ + +F K
Sbjct: 11 YFPYDYIYPEQFSYMLELKRTLDAKGHGVL-EMPSGTGKTVSLLALIVAYQRAFPLEVTK 69
Query: 60 VIYLARTHKQMDRVIEELKRI--------REIAKVSGIEFRSRKDLCLHSYIR--TFAQD 109
+IY +RT ++++VIEEL+++ E G+ SRK+LC+H + F +D
Sbjct: 70 LIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKD 129
Query: 110 AYTSMIVCKSL-KRLGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLEL--- 165
C SL + +Y ++ + E + P + +L L
Sbjct: 130 VDGK---CHSLTASYVRAQYQQDASLPHCRFYEEFDAHGRQVPLPAGIYNLDDLKALGQR 186
Query: 166 ---CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQA 222
CPY + R ANV+V SY Y+++P I L + +V+FDEAHN+ +
Sbjct: 187 QGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARK---AVVVFDEAHNIDNVC 243
Query: 223 ISALSDRLSIRSVER----------AIKEANEYGEKDIENFLSIFLRGLEIIYKEKLENY 272
I ++S L+ R+++R + E E+ + + + GL + +
Sbjct: 244 IDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDA 303
Query: 273 EISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVE-VGDAIREDKIERNLPPRSYVGRV 331
++ L + E V + E L FL+ ++E V +R + + PP G
Sbjct: 304 HLANPVLPDEVLQEAVPGSIRTAEH-FLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLA 362
Query: 332 GEF----------------LWNWISLADRSDY----------LHVFTREKGLALEIVALD 365
L + + +AD +D+ V T KG + I D
Sbjct: 363 QRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFD 422
Query: 366 ---PSVALEFL---------------EDVHSAILMSGTLSPLEAFRDIIGVN-------- 399
P++A L E S I+ SGTLSPL+ + I+ +
Sbjct: 423 DRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFT 482
Query: 400 ---ARLKKFPRMVKSENAIVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFT 456
AR+ P ++ N V ++ TR + + + E ++P + F
Sbjct: 483 MTLARVCLCPMIIGRGNDQVAISSKFETR---EDIAVIRNYGNLLLEMSAVVPDGIVAFF 539
Query: 457 ASYEVLEGLISTNVHIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNGGVLFG 514
SY+ +E +++ I E I K +FIE +D + + + AL +A G G +L
Sbjct: 540 TSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAET-SVALEKYQEACENGRGAILLS 598
Query: 515 VMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAH 573
V G+ SEG D+ VI+ G+PY R+ +A++ Y +F + + A
Sbjct: 599 VARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDF-LTFDAM 657
Query: 574 RKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
R AQ GR R + + G +V D R + LP W+ E + L L
Sbjct: 658 RHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNL 708
>pir||T38730 probable helicase - fission yeast (Schizosaccharomyces pombe)
>gi|2408082|emb|CAB16287.1| (Z99167) putative helicase
[Schizosaccharomyces pombe]
Length = 844
Score = 148 bits (371), Expect = 1e-34
Identities = 166/647 (25%), Positives = 279/647 (42%), Gaps = 86/647 (13%)
Query: 59 KVIYLARTHKQMDRVIEELKRIRE---IAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMI 115
K+ + +RTH Q+ ++++E+K++ + + SRK+LC+++ +R TS +
Sbjct: 213 KIYFTSRTHSQLQQLVQEIKKLNNQTFSTPIRVVSLASRKNLCINNEVRKLRP---TSAL 269
Query: 116 VCKSLKRLG---KCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLELCPYEVTR 172
K ++ G KC + ++ + D E + ++ E++E L++CPY TR
Sbjct: 270 NEKCIELQGSAHKCPFLQDNTQLWDFRDEALAEIMDIE----ELVELGQRLKVCPYYGTR 325
Query: 173 KVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSI 232
+ + A ++ Y ++ R A L L D I I DEAHNL D S S +S
Sbjct: 326 EAVDSAQIVTLPYPLLLQESARNA----LNLTLKDNICIIDEAHNLIDAICSMHSSSISF 381
Query: 233 RSVERAIKEANEY---------GE---------KDIENFLSIFLRGLEIIYKEKLENYE- 273
R V A + +Y G K + N S FL LE K+ N +
Sbjct: 382 RQVCIAETQLQQYFLRFEKRLNGNNRMHIKQLIKVVYNLKSFFLNCLETNTNSKVINVDS 441
Query: 274 ------ISEVPLSPASIFEHVSSI-------------LGLRERDLLRFLQ-EMVEVGDAI 313
++ L S + +VS + LG +E + L L+ E G+
Sbjct: 442 LLVSNGADQINLHHLSEYLNVSKLARKVDGYTKYMHSLGTQELESLNDLRSERFSNGNGY 501
Query: 314 REDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALEIVALDPSVALEFL 373
ED P + ++ FL N + A + L+ + LDPS +E L
Sbjct: 502 EED------PYTPVLMQLESFLLNIANPAPEGKLFYEKQTGDNPYLKYLLLDPSKHVEIL 555
Query: 374 -EDVHSAILMSGTLSPLEAFRDIIGVNARLKKFP----RMVKSEN-AIVLVARDVS---- 423
E S L GT+SP++ F ++ + + + P +V EN +LV++ +
Sbjct: 556 TEQCRSVNLAGGTMSPIDDFITLLFSDEQSRILPFSCDHIVPPENITTILVSQGPAGVPF 615
Query: 424 --TRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGKK 481
T + L K L + IIP V VF S+ L+ + I + K
Sbjct: 616 EFTHKRKDDENLLKDLGRTFQNFISIIPDGVVVFFPSFAFLQQAVKVWEMNGITNRLNAK 675
Query: 482 --VFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGI 539
+FIE +D + D ++ G G+LF V+GGR SEG ++S V++VG+
Sbjct: 676 KPLFIESKDFGDNPLDTFEHYKQSVDAGLSGMLFSVIGGRLSEGINFSDKLGRAVMVVGM 735
Query: 540 PYARPTP-RVQAQIRYYEKKFPGKG------RYYGYLLPAHRKLAQAAGRVHRSEEEKGS 592
P+ QA++ Y E+K KG Y R + Q+ GR R ++ S
Sbjct: 736 PFPNSQDVEWQAKVSYVEEKAKEKGINAKQASQEFYENTCMRAVNQSIGRAIRHRDDYAS 795
Query: 593 IVILDYRVLWNTVKRDLPDWMVETM--QPVTLPLMRIKLRKFWRAVK 637
I++LD R ++++R LP+W+ + + P P +R +L F+RA K
Sbjct: 796 IILLDSRYNRSSIQRKLPNWLSKNIHSSPNFGPAIR-QLATFFRAKK 841
>sp|P18074|XPD_HUMAN DNA-REPAIR PROTEIN COMPLEMENTING XP-D CELLS (XERODERMA PIGMENTOSUM
GROUP D COMPLEMENTING PROTEIN) (DNA EXCISION REPAIR
PROTEIN ERCC-2) >gi|105956|pir||S10888 ERCC2 protein -
human
Length = 760
Score = 146 bits (366), Expect = 5e-34
Identities = 176/714 (24%), Positives = 297/714 (40%), Gaps = 109/714 (15%)
Query: 4 YFPYKTLRPHQDEFI-ELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGY---K 59
YFPY + P Q ++ EL R + +G V+ E P+G GKT+S+LA ++ + ++ K
Sbjct: 11 YFPYDYIYPEQFSYMRELKRTLDAKGHGVL-EMPSGTGKTVSLLALIMAYQRAYPLEVTK 69
Query: 60 VIYLARTHKQMDRVIEELKRIREIAKVS--------GIEFRSRKDLCLHSYIRT--FAQD 109
+IY +RT ++++VIEEL+++ + G+ SRK+LC+H + F +D
Sbjct: 70 LIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKD 129
Query: 110 AYTSMIVCKSLKR-LGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLEL--- 165
C SL + +Y + + E + P + +L L
Sbjct: 130 VDGK---CHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRR 186
Query: 166 ---CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQA 222
CPY + R ANV+V SY Y+++P I L + +V+FDEAHN+ +
Sbjct: 187 QGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARK---AVVVFDEAHNIDNVC 243
Query: 223 ISALSDRLSIRSVERA-------------IKEANEYGEKDIENFLSIFLRGLEIIYKEKL 269
I ++S L+ R+++R IKE +E +D L + GL +
Sbjct: 244 IDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRL---VEGLREASAARE 300
Query: 270 ENYEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVE-VGDAIREDKIERNLPPRSYV 328
+ ++ L + E V + E L FL+ ++E V +R + + PP
Sbjct: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEH-FLGFLRRLLEYVKWRLRVQHVVQESPPAFLS 359
Query: 329 GRVGEF----------------LWNWISLADRSDYLH----------VFTREKGLALEIV 362
G L + + + D +D+ V T KG + I
Sbjct: 360 GLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIE 419
Query: 363 ALD---PSVALEFL---------------EDVHSAILMSGTLSPLEAFRDIIGVN----- 399
D P++A L E S I+ SGTLSPL+ + I+ +
Sbjct: 420 PFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMA 479
Query: 400 ------ARLKKFPRMVKSENAIVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVG 453
AR+ P ++ N V ++ TR + + + + E ++P +
Sbjct: 480 TFTMTLARVCLCPMIIGRGNDQVAISSKFETREDI---AVIRNYGNLLLEMSAVVPDGIV 536
Query: 454 VFTASYEVLEGLISTNVHIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNGGV 511
F SY+ +E +++ I E I K +FIE +D + + + AL +A G G +
Sbjct: 537 AFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAET-SVALEKYQEACENGRGAI 595
Query: 512 LFGVMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLL 570
L V G+ SEG D+ VI+ G+PY R+ +A++ Y +F + +
Sbjct: 596 LLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDF-LTF 654
Query: 571 PAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
A R AQ GR R + + G +V D R + LP W+ E + L L
Sbjct: 655 DAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNL 708
>emb|CAA36463.1| (X52221) ercc2 gene product [Homo sapiens]
Length = 730
Score = 146 bits (366), Expect = 5e-34
Identities = 176/714 (24%), Positives = 297/714 (40%), Gaps = 109/714 (15%)
Query: 4 YFPYKTLRPHQDEFI-ELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGY---K 59
YFPY + P Q ++ EL R + +G V+ E P+G GKT+S+LA ++ + ++ K
Sbjct: 11 YFPYDYIYPEQFSYMRELKRTLDAKGHGVL-EMPSGTGKTVSLLALIMAYQRAYPLEVTK 69
Query: 60 VIYLARTHKQMDRVIEELKRIREIAKVS--------GIEFRSRKDLCLHSYIRT--FAQD 109
+IY +RT ++++VIEEL+++ + G+ SRK+LC+H + F +D
Sbjct: 70 LIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKD 129
Query: 110 AYTSMIVCKSLKR-LGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLEL--- 165
C SL + +Y + + E + P + +L L
Sbjct: 130 VDGK---CHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRR 186
Query: 166 ---CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQA 222
CPY + R ANV+V SY Y+++P I L + +V+FDEAHN+ +
Sbjct: 187 QGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARK---AVVVFDEAHNIDNVC 243
Query: 223 ISALSDRLSIRSVERA-------------IKEANEYGEKDIENFLSIFLRGLEIIYKEKL 269
I ++S L+ R+++R IKE +E +D L + GL +
Sbjct: 244 IDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRL---VEGLREASAARE 300
Query: 270 ENYEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVE-VGDAIREDKIERNLPPRSYV 328
+ ++ L + E V + E L FL+ ++E V +R + + PP
Sbjct: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEH-FLGFLRRLLEYVKWRLRVQHVVQESPPAFLS 359
Query: 329 GRVGEF----------------LWNWISLADRSDYLH----------VFTREKGLALEIV 362
G L + + + D +D+ V T KG + I
Sbjct: 360 GLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIE 419
Query: 363 ALD---PSVALEFL---------------EDVHSAILMSGTLSPLEAFRDIIGVN----- 399
D P++A L E S I+ SGTLSPL+ + I+ +
Sbjct: 420 PFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMA 479
Query: 400 ------ARLKKFPRMVKSENAIVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVG 453
AR+ P ++ N V ++ TR + + + + E ++P +
Sbjct: 480 TFTMTLARVCLCPMIIGRGNDQVAISSKFETREDI---AVIRNYGNLLLEMSAVVPDGIV 536
Query: 454 VFTASYEVLEGLISTNVHIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNGGV 511
F SY+ +E +++ I E I K +FIE +D + + + AL +A G G +
Sbjct: 537 AFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAET-SVALEKYQEACENGRGAI 595
Query: 512 LFGVMGGRNSEGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLL 570
L V G+ SEG D+ VI+ G+PY R+ +A++ Y +F + +
Sbjct: 596 LLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDF-LTF 654
Query: 571 PAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
A R AQ GR R + + G +V D R + LP W+ E + L L
Sbjct: 655 DAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNL 708
>pir||A72723 hypothetical protein APE0322 - Aeropyrum pernix (strain K1)
>gi|5103961|dbj|BAA79277.1| (AP000059) 549aa long
hypothetical protein [Aeropyrum pernix]
Length = 549
Score = 137 bits (341), Expect = 4e-31
Identities = 139/518 (26%), Positives = 242/518 (45%), Gaps = 62/518 (11%)
Query: 117 CKSLKRLGKCKYFENLKEKRDKVKEIVEFFLENP-----SYPWEVIEYSNLLELCPYEVT 171
C+ + G C Y+E L + E+ ++ P W++ ++ CP+
Sbjct: 41 CRIARAKGVCSYYEELSRLDEA--EVAQYVRSRPVISAYRLAWDIAKFKGA---CPFFAL 95
Query: 172 RKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSD-RL 230
+ + E + IVA+Y Y+ I ++FL+ +Y D + + DEAH+L + I +L + R+
Sbjct: 96 KGLVEDSQFIVATYPYLFKEDIFRSFLEPY--DYGDFVAVVDEAHSLLN--IHSLHEYRV 151
Query: 231 SIRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLENYEISEVPLSPASIFEHVSS 290
S R ++ A+KE EY + F+ LE + K K ++S + L F
Sbjct: 152 SQRDLDLALKEVREYASSARD-----FIAWLESVLK-KASRLKVSRITLLDKQPF----- 200
Query: 291 ILGLRERDLLRFLQEMVEVGDAIREDKIER--NLPPRSYVGRVGEF---LWNWISLADRS 345
L D L ++++VE IR K E +L S +GRV +++W+S+ R
Sbjct: 201 ---LEGLDDLSVVEDVVET---IRARKAEEALSLSGPSGIGRVKTMASRIYSWLSVLVRD 254
Query: 346 DYLHVFTREKGLALEIVA--LDPS-VALEFLEDVHSAILMSGTLSPLEAFRDIIGVNARL 402
D +++G L ++A LDPS V E LE V +A+L+SGT+ + + +++GV +R
Sbjct: 255 DSYLFAEKDEGGVLWLIATPLDPSRVVKEPLEKVKAAVLLSGTMPSTKLYMEVLGV-SRS 313
Query: 403 KKFPRMVKSENA------IVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFT 456
KF + A +VA DV+T R +Y+ +A I A +++P
Sbjct: 314 FKFVDVNLMYGARGFGRFFTIVAADVTTAYRSRGDSMYRLIASRIAMADRLLPGLKLAVY 373
Query: 457 ASYEVLEGLISTNVHIRIEEEIGKKVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVM 516
SYEV+ ++ R+ ++ + +E R S E +A + A G ++ V
Sbjct: 374 PSYEVMYRVVE-----RLPADV--ETIVETRGISLDEVEAKIL---ARDPGEKIIINAVA 423
Query: 517 GGRNSEG---QDYSG-DEMNGVILVGIPYARPTPRVQAQIRYYEKKF-PGKGRYYGYLLP 571
GG+ EG DY G + ++ VI+VG+P+ +P + + + R YL+
Sbjct: 424 GGKLVEGVEFVDYEGRNLLSTVIVVGVPFPQPDDYTRKHLEVMASRIGVSNARKLVYLVN 483
Query: 572 AHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDL 609
K+ QA GR R E++ +++DYR L +K L
Sbjct: 484 PMIKVRQALGRGIRGPEDRALYILMDYRYLRRDLKEVL 521
>gb|AAD33587.1|AF132140_1 (AF132140) excision repair protein ERCC2/XPD [Drosophila
melanogaster] >gi|7291258|gb|AAF46689.1| (AE003453) Xpd
gene product [Drosophila melanogaster]
Length = 745
Score = 136 bits (339), Expect = 7e-31
Identities = 160/695 (23%), Positives = 291/695 (41%), Gaps = 118/695 (16%)
Query: 18 IELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGY---KVIYLARTHKQMDRVI 74
+EL R + +G ++E P+G GKT ++L+ ++ + + K+IY +RT ++++VI
Sbjct: 2 LELKRSLDAKGH-CLLEMPSGTGKTATLLSLIVAYMVEHPETVRKLIYCSRTVPEIEKVI 60
Query: 75 EELKRIREIAK--------VSGIEFRSRKDLCLHSYIRTF----AQDAYTSMIVCKSLKR 122
EL+ + + +G+ SRK++C+H + A D + ++
Sbjct: 61 AELQNLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRE 120
Query: 123 LGK-------CKYFENLK-EKRDKVKEIVEFFLENPSYPWEVIEYSNLLELCPYEVTRKV 174
+ C+YFE E ++ + + ++ ++ EY CPY + R
Sbjct: 121 RHEMDTETPICQYFEGFSLEGKESTLPVGVYSID------DLKEYGRSRNWCPYFLARYA 174
Query: 175 GEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRS 234
A+++V SY Y+++P I Q + E V+FDEAHN+ + I ++S +++ R+
Sbjct: 175 IAHAHIVVYSYHYLLDPKIAQVVSKEMSRESC---VVFDEAHNIDNVCIDSMSVKINRRT 231
Query: 235 VERAIKEAN-------EYGEKDIENFLSIFLRGLE-------------IIYKEKLENYEI 274
VER+ N + E+D + R ++ I+ L N +
Sbjct: 232 VERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASVQRDTDMILANPVLPNDVL 291
Query: 275 SEVPLSPASIFEHVSSILGLRERDLLRFLQEMVEVGDAIREDK------------IERNL 322
+EV +H S L R + +++ + V ++E IER
Sbjct: 292 TEVVPGNIRNADHFLSFL----RRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIERK- 346
Query: 323 PPRSYVGRVGEFLWNWISLADRSDY----------LHVFTREKGLA-------------- 358
P R R+ L + ++D ++Y V T KG
Sbjct: 347 PLRFCAERLSSLL-RTLEISDLTEYGALTLITHFATLVSTYTKGFTIIIEPFDDKTPTVS 405
Query: 359 ---LEIVALDPSVALE-FLEDVHSAILMSGTLSPLEAFRDIIGVN-----------ARLK 403
L LD S+A+ + ++ SGTLSP++ + I+ + AR
Sbjct: 406 NPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPC 465
Query: 404 KFPRMVKSENAIVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLE 463
P +V N V ++ TR + + + + + E K +P + F SY LE
Sbjct: 466 LLPMIVSKGNDQVTISSKFETREDT---AVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLE 522
Query: 464 GLISTNVHIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNS 521
++++ I + + K +FIE +D ++ + AL+ KA G G VL V G+ S
Sbjct: 523 SVVASWYDQGIVDTLLRYKLLFIETQD-NAETSYALMNYVKACDCGRGAVLLAVARGKVS 581
Query: 522 EGQDYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAA 580
EG D+ V++ GIPY R+ +A++ Y +F + + A R AQ
Sbjct: 582 EGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRENDF-LTFDAMRHAAQCV 640
Query: 581 GRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVE 615
GR R + + G ++ D R + + LP W+ E
Sbjct: 641 GRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQE 675
>pir||T21356 hypothetical protein F25H2.13 - Caenorhabditis elegans
>gi|3876338|emb|CAB02102.1| (Z79754) similar to
DEAH-type helicase~cDNA EST yk3b8.5 comes from this
gene~cDNA EST yk3b8.3 comes from this gene~cDNA EST
yk35b1.5 comes from this gene~cDNA EST yk421c9.3 comes
from this gene~cDNA EST yk421c9.5 comes from this
gene~cDNA EST yk277h10.> >gi|3876497|emb|CAB05720.1|
(Z83224) similar to DEAH-type helicase~cDNA EST yk3b8.5
comes from this gene~cDNA EST yk3b8.3 comes from this
gene~cDNA EST yk35b1.5 comes from this gene~cDNA EST
yk421c9.3 comes from this gene~cDNA EST yk421c9.5 comes
from this gene~cDNA EST yk277h10.>
Length = 994
Score = 132 bits (329), Expect = 1e-29
Identities = 174/766 (22%), Positives = 313/766 (40%), Gaps = 154/766 (20%)
Query: 2 FEYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLP---------- 51
F + PY+ R F++ V DV+ R +E+PTG GKT+S+L L
Sbjct: 21 FPFEPYECQRI----FMKNVVDVLDRKLDAALESPTGTGKTLSLLCSTLAWVQRQKETKP 76
Query: 52 ------------------HAISFGY--KVIYLARTHKQMDRVIEELKRIREIAKVSGIEF 91
+ Y + Y +RTH Q+++V+ EL R E V
Sbjct: 77 LDFATWQTSGAGGAEKTDEKLKSAYVPTIFYASRTHSQLEQVVHELNRT-EYKWVKTTIL 135
Query: 92 RSRKDLCLHSYIRTFAQDAYTSMIVCKSLKRLGKCKYFENLKEKRDKVKEIVEFFLENPS 151
SR+ C++ ++ +++ VC+ L C Y+ K ++ EF + +
Sbjct: 136 GSREHFCINQKVKKI-KESNRQAHVCRGLVSKRACHYYN--KFDACTTDKMTEFLDKGEA 192
Query: 152 YPWE-VIEYSNLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIV 210
E ++ LCPY ++R+ E A +I+ Y Y+++P +R+ + L+ + IV
Sbjct: 193 MDIEDFVKLGTQNSLCPYFMSRQRSETAELILLPYNYIIDPKMRRRYK----LDLKNSIV 248
Query: 211 IFDEAHNLPDQAISALSDRLS----------IRSVERAIKEANEYGEKDIENFLSIFLRG 260
IFDEAHNL S S L+ ++ V + + E + + F
Sbjct: 249 IFDEAHNLESICESNASAELTSTSIALCIEELKKVLALLVDEEETARSEADAETGAFGSA 308
Query: 261 LEIIYKEKLENYEISEVPLSPASIF---EHVSSILGLRERDLLRFLQEMVEVGDAIRE-- 315
+ K+ +EN ++ IF E + + G + + L G+ + E
Sbjct: 309 KIDLTKKLIENLRTEDLMTVLEKIFSLEEEMDKLFGSSQLKSVPPLSGKASDGEILLETL 368
Query: 316 ------------------DKIERNLPPRSYVG---------RVGEFLWN----------- 337
D I L V +V +FL +
Sbjct: 369 AKAGFDANSVERLVDVLRDAISYLLSKNEEVALTEKGDGMEKVADFLLSIYSTHAQDVAA 428
Query: 338 -----WISLADRSD----------YLHVFTREKGLALEIVALDPSVALEFLE--DVHSAI 380
+ L DR D Y+ + L ++ S+++ L+ V + +
Sbjct: 429 AVGEETVKLVDRVDPKTVARNCKLYIQKDKDNEKLTIKYFCFQASISMRMLKMRGVRNVL 488
Query: 381 LMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAI--VLVARDVSTRG---------EER 429
L SGTLSP++AF +G+N F ++++E+A+ V V + TRG + R
Sbjct: 489 LASGTLSPIQAFTYNMGLN-----FGAILENEHALKQVPVLTSIVTRGKRGGLAGSFQNR 543
Query: 430 SPVLYKK-LAEYIFEAVKIIPKNVGVFTASYEVLEGLIST----------NVHIRIEEEI 478
+ Y +AE + +++IP+ + +F +SY ++ L++T N + E
Sbjct: 544 KNLDYVTGVAEALLRVMEVIPQGILIFFSSYSQMDELVATWKTTKWSSNSNESFWEKMEK 603
Query: 479 GKKVFIEKRDASSSENDALVAEF-KAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILV 537
K+V +E R + E A+ + + ++ +G L V G+ SEG D+ E VI++
Sbjct: 604 TKRVVVEPR--AKEELAAIRLRYTQGVSEQHGAALLAVCRGKVSEGIDFCDAESRAVIII 661
Query: 538 GIPYAR-PTPRVQAQIRYY-------EKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEE 589
GIPY RV + Y + K + Y + A R + QA GRV R +++
Sbjct: 662 GIPYPPIHDERVVLKKMYLDDLMGRKDTKSERQSSQDWYQMEAFRAVNQAIGRVLRHKDD 721
Query: 590 KGSIVILDYRVLWNTVKRDL-PDWMVETMQPVTLPLMRIKLRKFWR 634
G++V++D R + + K ++ P W+ T+ +K +F++
Sbjct: 722 FGTVVLMDTR--YASAKPEMFPKWLRNTISRSDTDGCALKTSRFFK 765
>gb|AAF09041.1|AC011717_8 (AC011717) hypothetical protein; 30600-24965 [Arabidopsis thaliana]
Length = 959
Score = 123 bits (305), Expect = 7e-27
Identities = 164/698 (23%), Positives = 288/698 (40%), Gaps = 129/698 (18%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEK--VIIEAPTGFGKTISVLAGVLPHAISFGY---- 58
FP++ +Q + I + R + K ++E+PTG GKT+ +L L S G
Sbjct: 58 FPFEA---YQSQIIYMDRVIESLQNKCHALLESPTGTGKTLCLLCATLAWRKSLGSFSTR 114
Query: 59 -----------------------------KVIYLARTHKQMDRVIEELKRIREIAKVSGI 89
++Y +RTH Q+ +VI+ELKR K+ +
Sbjct: 115 KDRKNSAIPWSDSDEPLSQSGGGGGGAFPTIVYASRTHSQLRQVIKELKRSSYRPKM--V 172
Query: 90 EFRSRKDLCLHSYIRTFAQDAYTSMIVCKSL-KRLGK--CKYFENLKEKRDKVKEIVEFF 146
SR+ LC++ + + A T+ C+ L K+ GK C +F L ++
Sbjct: 173 VLGSREQLCVNEEVNSLRGKALTN--ACQYLCKKRGKRQCNHFNRLP----------DYL 220
Query: 147 LENPSYPWEVIEYSNLLEL------CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDG 200
NP E ++ +L+ + CPY +TR++ + ++I A Y Y+++ R+
Sbjct: 221 KHNPHIGDEPVDIEDLVNIGKDSGPCPYYITRELHKDVDIIFAPYNYLISNGYRKF---- 276
Query: 201 LGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIKEANE-----YGEKDIENFLS 255
L + +++ ++IFDEAHNL + S L + I EA E +D N +S
Sbjct: 277 LKVNWTNSVLIFDEAHNLESLCADSASFDLPSVLLSACISEAQECVQLAAARRDSLNDVS 336
Query: 256 IFLRGLEIIYKEKLENYE-ISEVPL--------SPASIFEHVSSILGLRERDLLRFLQEM 306
I I+ L+ E IS+VP+ P + L + + + +
Sbjct: 337 INPENFAILKGLLLKLQELISKVPIPKRDEGFTKPGPYIYEMLKSLNITHETAPKLIGTV 396
Query: 307 VEVGDAIREDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALEIV---- 362
E + E+K S + + + L I + S++ V+ + + +++
Sbjct: 397 EEAAVFLEEEKQRTATNAGSKLEIIADML-KLIFRENGSNHADVYRELEQNSTDVMKGKV 455
Query: 363 -------ALDPSVALEFL--EDVHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSEN 413
P + + + + V S IL SGTLSP+++ + ++ ++ V S N
Sbjct: 456 SRTLSWWCFSPGITMLDIAQKGVGSIILTSGTLSPMDSLAQELKLDFPIRLENPHVISSN 515
Query: 414 AIVLVARDVSTRG--------EERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGL 465
+ G P ++L I +++P+ + +F SY +++
Sbjct: 516 QLWAGVVSTGPSGYVLNSSYRNRDVPEYKQELGNAIVNFSRVVPEGLLIFFPSYYLMDSC 575
Query: 466 I----------STNVHIRIEEEIGKKVFIEKRDASSSENDALVAEFKAEAKG---NGGVL 512
I S V RI + KK IE +D SS A + +F + + +G V
Sbjct: 576 ITFWKNGCYRNSMTVWERICKL--KKPVIEPKD--SSLFPAAMRDFSEKLQDRATSGVVF 631
Query: 513 FGVMGGRNSEGQDYSGDEMNGVILVGIPYARPT-PRVQAQIRYYEK-------KFPGKGR 564
F V G+ SEG D++ V++ G+PYAR T PRV+ + + ++ K P
Sbjct: 632 FAVCRGKVSEGLDFADGAGRAVVITGLPYARVTDPRVKLKREFLDEQSQLADVKLPRSTL 691
Query: 565 YYG---YLLPAHRKLAQAAGRVHRSEEEKGSIVILDYR 599
G Y A R + QA GRV R + G+I+ D R
Sbjct: 692 LSGSMWYSQEAARAVNQAIGRVIRHRHDYGAIIFCDDR 729
>gb|AAD55463.1|AC009322_3 (AC009322) Hypothetical protein [Arabidopsis thaliana]
Length = 912
Score = 111 bits (276), Expect = 2e-23
Identities = 162/684 (23%), Positives = 279/684 (40%), Gaps = 148/684 (21%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEK--VIIEAPTGFGKTISVLAGVLPHAISFGY---- 58
FP++ +Q + I + R + K ++E+PTG GKT+ +L L S G
Sbjct: 58 FPFEA---YQSQIIYMDRVIESLQNKCHALLESPTGTGKTLCLLCATLAWRKSLGSFSTR 114
Query: 59 -----------------------------KVIYLARTHKQMDRVIEELKRIREIAKVSGI 89
++Y +RTH Q+ +VI+ELKR K+ +
Sbjct: 115 KDRKNSAIPWSDSDEPLSQSGGGGGGAFPTIVYASRTHSQLRQVIKELKRSSYRPKM--V 172
Query: 90 EFRSRKDLCLHSYIRTFAQDAYTSMIVCKSL-KRLGK--CKYFENLKEKRDKVKEIVEFF 146
SR+ LC++ + + A T+ C+ L K+ GK C +F L ++
Sbjct: 173 VLGSREQLCVNEEVNSLRGKALTN--ACQYLCKKRGKRQCNHFNRLP----------DYL 220
Query: 147 LENPSYPWEVIEYSNLLEL------CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDG 200
NP E ++ +L+ + CPY +TR++ + ++I A Y Y+++ R+
Sbjct: 221 KHNPHIGDEPVDIEDLVNIGKDSGPCPYYITRELHKDVDIIFAPYNYLISNGYRKF---- 276
Query: 201 LGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIKEANE-----YGEKDIENFLS 255
L + +++ ++IFDEAHNL + S L + I EA E +D N +S
Sbjct: 277 LKVNWTNSVLIFDEAHNLESLCADSASFDLPSVLLSACISEAQECVQLAAARRDSLNDVS 336
Query: 256 IFLRGLEIIYKEKLENYE-ISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVEVGDAIR 314
I I+ L+ E IS+VP+ +RD F + + + ++
Sbjct: 337 INPENFAILKGLLLKLQELISKVPIP---------------KRD-EGFTKPGPYIYEMLK 380
Query: 315 EDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALEIVALDPSVALEFLE 374
I P+ +G V E VF E+ + A + LE +
Sbjct: 381 SLNITHETAPK-LIGTVEE--------------AAVFLEEE---KQRTATNAGSKLEIIA 422
Query: 375 DVHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVLVARDV------------ 422
D+ I + + +R I+ + K+ ++ EN V+ + +
Sbjct: 423 DMLKLIFRENGSNHADVYRLIMETSFFGKRRDFPIRLENPHVISSNQLWAGVVSTGPSGY 482
Query: 423 ---STRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLI----------STN 469
S+ P ++L I +++P+ + +F SY +++ I S
Sbjct: 483 VLNSSYRNRDVPEYKQELGNAIVNFSRVVPEGLLIFFPSYYLMDSCITFWKNGCYRNSMT 542
Query: 470 VHIRIEEEIGKKVFIEKRDASSSENDALVAEFKAEAKG---NGGVLFGVMGGRNSEGQDY 526
V RI + KK IE +D SS A + +F + + +G V F V G+ SEG D+
Sbjct: 543 VWERICKL--KKPVIEPKD--SSLFPAAMRDFSEKLQDRATSGVVFFAVCRGKVSEGLDF 598
Query: 527 SGDEMNGVILVGIPYARPT-PRVQAQIRYYEK-------KFPGKGRYYG---YLLPAHRK 575
+ V++ G+PYAR T PRV+ + + ++ K P G Y A R
Sbjct: 599 ADGAGRAVVITGLPYARVTDPRVKLKREFLDEQSQLADVKLPRSTLLSGSMWYSQEAARA 658
Query: 576 LAQAAGRVHRSEEEKGSIVILDYR 599
+ QA GRV R + G+I+ D R
Sbjct: 659 VNQAIGRVIRHRHDYGAIIFCDDR 682
>gb|AAK40649.1| DNA helicase [Sulfolobus solfataricus]
Length = 550
Score = 109 bits (270), Expect = 9e-23
Identities = 141/604 (23%), Positives = 253/604 (41%), Gaps = 82/604 (13%)
Query: 10 LRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGYKVIYLARTHKQ 69
LR Q + E + + ++ V ++APTG GKT+ L A+ KV ++ RTH +
Sbjct: 3 LREWQSKIAEKIVEALRNNFLVSLQAPTGSGKTLFALYT----ALKVKPKVAFVVRTHNE 58
Query: 70 MDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSLKRLGKCKYF 129
V EL + K + +S C+ S AQD Y C
Sbjct: 59 FFPVYRELSLHFKDKKYGFLVGKS--SACVFSSSDVDAQDIY--------------CNGC 102
Query: 130 ENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLELCPYEVTRKVGEKANVIVASYLYMV 189
E V + + L ++ E L CPY + + A+VI+ +Y Y+
Sbjct: 103 EIFNASAVTVTDSPKVSLN------KLKEEGKKLGFCPYYSLLETIKTADVILLTYPYLF 156
Query: 190 NPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIKEANEYGEKD 249
PW+R++ L + + D +VI DEAHN+ + + +L+ R +E AI +++ K
Sbjct: 157 IPWLRES----LDINWEDYVVIVDEAHNI-ENVSNIEEKKLNKRIIEMAISQSHSQNVKV 211
Query: 250 IENFLSIFLRGLEIIYKEKLENYEISEVPLSPASIFEHVSSILGLRERDLLRFLQEMVEV 309
I L + + +Y E + Y + E + + +IL E ++ + E
Sbjct: 212 ILERLKENVE--KAVYSE--DKYILIEK--------DKLDNILPSNEE-----IEILSEE 254
Query: 310 GDAIREDKIERNLPPRSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALEIVALDPSVA 369
D IR+ I+ R+Y+G + F L + + + VF+ L + + PS
Sbjct: 255 YDEIRKIMIKNKTVSRNYLGSILRF----FDLVN-DEGIRVFSYSGSLIAKYII--PSYF 307
Query: 370 LEFLEDVH-SAILMSGTLSPLEAFRDIIGVNARL-----KKFPRMVKSENAIVLVARDVS 423
+ L D + +LMSGT+ PL+ R+IIG+ ++ +K + + L++ DV+
Sbjct: 308 TDILNDEKITYMLMSGTMQPLDYLRNIIGIKRKILYIDAEKVMKKRLTGTYECLISIDVT 367
Query: 424 TRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGKKVF 483
T RS + +K A Y+ + ++V SYE + ++S ++IR E
Sbjct: 368 TTYSLRSEQMARKYASYLLKIFYNSRRHVLAIFPSYEFMR-IVSKFLNIRYLAE------ 420
Query: 484 IEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEG---QDYSGDEMNGVILVGIP 540
+ + + E + K ++ G+ G+ +EG + ++ V +VGIP
Sbjct: 421 ---------DTETSIEEIMSNLKKEKTIIMGIARGKLAEGIEIVENGSSLISDVAMVGIP 471
Query: 541 YARPTPRVQAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILD--Y 598
Y ++ ++ K + A + Q+ GR R + +I +LD Y
Sbjct: 472 YPPIDDYLKIRVEEISKILKKDISNELISIQALIAVKQSIGRAIRGPTDNATIWLLDKRY 531
Query: 599 RVLW 602
LW
Sbjct: 532 DSLW 535
>pir||T23694 hypothetical protein M03C11.2 - Caenorhabditis elegans
>gi|3878642|emb|CAA88959.1| (Z49128) similar to CHL1
protein~cDNA EST yk392d9.3 comes from this gene~cDNA EST
yk392d9.5 comes from this gene~cDNA EST yk429f8.3 comes
from this gene~cDNA EST yk429f8.5 comes from this
gene~cDNA EST yk576a7.3 comes from this gene~cDNA EST
yk576a7.5 >
Length = 848
Score = 104 bits (258), Expect = 2e-21
Identities = 151/678 (22%), Positives = 275/678 (40%), Gaps = 119/678 (17%)
Query: 59 KVIYLARTHKQMDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCK 118
K+ Y +RTH Q++++ EEL + R ++ + SR LC++ ++ + + C
Sbjct: 185 KIFYASRTHSQLEQLAEELAKTRFQPRI--VTCASRGTLCVNEEVKKLKLNHLINE-KCM 241
Query: 119 SLKRLG-----KCKYFENLKEKRDK-------------VKEIVEFFLENP-SYPWEVIEY 159
L++ G K + E K+ K ++++V L N EV +
Sbjct: 242 ELRKNGMSEKEKVQKLEKGTTKKTKTCATSCEFYNSTQIEDVVNGVLSNKLKSTLEVSKQ 301
Query: 160 SNLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLP 219
L CPY TRK + +++ Y +++ R+A+ G+E D +++ DEAHN+
Sbjct: 302 GKLSNGCPYFATRKSVPQCQLVLLPYQVLLHDGTRKAW----GIELKDNVIVLDEAHNVL 357
Query: 220 D------------------QAISALSDRLSIRSVERAIKEANEYGE-------------- 247
+ + S S +S +S+ A++ EY
Sbjct: 358 NTISSFFFRKLEKVSKNGFKNCSLYSAEISTKSLTLALRLIREYNAHYKLKLLAHNLLYM 417
Query: 248 KDIENFLSIFLRGLEIIYKEKL-------ENYEISEVPLSPASIFEHVSSILGL------ 294
K +E+ S L L KE + N I E+ L + + + +
Sbjct: 418 KQLESLTSKMLIFLNSQSKEDVMTMAQLARNLNILEINLFKLAEYMEKTDLCKKFHGFYM 477
Query: 295 ----------RERDLLRFLQEMVEVGDAIREDKIERNLPPRSYVGRVGEFLWNWISLADR 344
E+ L +Q+++ +A E + E PP+ + +L ++
Sbjct: 478 RLQKEEIKKENEKPKLTGIQKLMAAKEAEPEPEAEPLPPPKPVPSPLFSLKSFIDALTNK 537
Query: 345 SDYLHVFTREKGLALEI--VALDPSVAL-EFLEDVHSAILMSGTLSPLEAF-----RDII 396
+ + + + + L+P+ L E + + IL+ GT+ P + R I
Sbjct: 538 CEDGRIIVEKSATEAKFRFMLLNPADRLSEVVTSARATILVGGTMEPAQLLVETLSRGSI 597
Query: 397 GVNARLKKFPR---MVKSENAIVLVARDVS---------TRGEERSPVLYKKLAEYIFEA 444
G ++ +++F + S+ V V R V TRG + + + LA I
Sbjct: 598 GADS-IRRFSCCHVIDDSQLLAVTVERTVDGKPFQLTYQTRGADTT---LRSLATSIQAL 653
Query: 445 VKIIPKNVGVFTASYEVL----EGLISTNVHIRIEEEIGKKVFIEKRDASSSENDALVAE 500
+ IP V +F SY+ L + + + RIEE+ K VF E R +S D
Sbjct: 654 IPHIPNGVVIFVPSYDFLFNFQKKMKEFGILKRIEEK--KAVFTESRQPTSDVWDRFS-- 709
Query: 501 FKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYARPTP-RVQAQIRYYEKKF 559
+A G +LF V+GG+ SEG ++ + VI++G+PY T ++ ++++ + +
Sbjct: 710 -RAAKTSKGAILFAVVGGKMSEGINFCDELGRAVIVIGLPYPNKTSVELRERMKFLDTQM 768
Query: 560 PGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQP 619
P G L H + QA GR R + ++ + D R + +R L W+ + Q
Sbjct: 769 PNGGNLLYESLCMH-AVNQAIGRAIRHRRDYAAVYLFDDRYAKESTRRKLSTWIGDRTQ- 826
Query: 620 VTLPLMRI--KLRKFWRA 635
V L I K R F+ A
Sbjct: 827 VKLGFGEIIRKTRSFFEA 844
>gb|AAB62733.1| (U77066) RepD [Dictyostelium discoideum]
Length = 776
Score = 101 bits (250), Expect = 2e-20
Identities = 74/286 (25%), Positives = 137/286 (47%), Gaps = 38/286 (13%)
Query: 4 YFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAI-SFGYKVIY 62
YFPY + P Q ++ ++ + G I+E P+G GKT+S+L+ + + + + K+IY
Sbjct: 11 YFPYSYIYPEQYSYMVALKRSLDNGGPCILEMPSGTGKTVSLLSLISSYQVKNPSIKLIY 70
Query: 63 LARTHKQMDRVIEELKRI---------REIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTS 113
+RT ++++ EE +R+ E K + SR++LC+ + + +D
Sbjct: 71 CSRTVPEIEQATEEARRVLQYRNSEMGEESPKTLCMSMSSRRNLCIQPRV-SEERDGKVV 129
Query: 114 MIVCKSL--------KRLGKCKYFENLKEKRDKVKEIVEFFLENPSYPWEVIEYSNLLEL 165
+C+ L KCK+FEN + E LE ++ EY ++
Sbjct: 130 DALCRELTSSWNRESPTSEKCKFFENFESNGK------EILLEGVYSLEDLKEYGLKHQM 183
Query: 166 CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISA 225
CPY ++R + AN+++ SY Y+++P I S+ IV+FDEAHN+ + I+A
Sbjct: 184 CPYFLSRHMLNFANIVIFSYQYLLDPKIASLISSSFP---SNSIVVFDEAHNIDNVCINA 240
Query: 226 LSDRL----------SIRSVERAIKEANEYGEKDIENFLSIFLRGL 261
LS + +I + + I++ + EK +++ + GL
Sbjct: 241 LSINIDNKLLDTSSKNIAKINKQIEDIKKVDEKRLKDEYQRLVNGL 286
Score = 86.6 bits (211), Expect = 8e-16
Identities = 78/287 (27%), Positives = 131/287 (45%), Gaps = 17/287 (5%)
Query: 360 EIVALDPSVALEFLEDVH-SAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIV-- 416
+ LD S+ ++ + D + S ++ SGTLSPL+ + ++ + + M + N I
Sbjct: 427 QFCCLDASIGMKPIFDKYRSVVITSGTLSPLDIYTKMLNFRPTVVERLTMSLNRNCICPC 486
Query: 417 LVAR-----DVSTRGEERSPV-LYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNV 470
++ R +ST+ + RS + + + E I+P + F SY +E ++S
Sbjct: 487 ILTRGSDQISISTKFDVRSDTAVVRNYGALLVEVSAIVPDGIICFFTSYSYMEQIVSVWN 546
Query: 471 HIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSG 528
+ + I K +F+E D + S AL KA G G VL V G+ SEG D+
Sbjct: 547 EMGLLNNILTNKLIFVETSDPAESAL-ALQNYKKACDSGRGAVLLSVARGKVSEGIDFDN 605
Query: 529 DEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSE 587
VIL GIPY +V +A++ + ++ + + A R +Q GRV R +
Sbjct: 606 QYGRCVILYGIPYINTESKVLRARLEFLRDRYQIRENEF-LTFDAMRTASQCVGRVIRGK 664
Query: 588 EEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL---MRIKLRK 631
+ G ++ D R + LP W+++ QP L L M I L K
Sbjct: 665 SDYGIMIFADKRYNRLDKRNKLPQWILQFCQPQHLNLSTDMAISLSK 711
>pir||E83413 hypothetical protein PA1866 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9947855|gb|AAG05255.1|AE004612_9
(AE004612) hypothetical protein [Pseudomonas aeruginosa]
Length = 758
Score = 96.0 bits (235), Expect = 1e-18
Identities = 151/637 (23%), Positives = 251/637 (38%), Gaps = 96/637 (15%)
Query: 5 FPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAISFGYKVIYLA 64
FP+ R Q + E V G ++ +APTG GKTI L L A
Sbjct: 185 FPHAEFRHGQRQLAEAVYKAASAGCCLMAQAPTGIGKTIGTLFPQLK------------A 232
Query: 65 RTHKQMDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSLKRLG 124
+++DR+ AK G + L LH+ + + V + + R
Sbjct: 233 MPGQRLDRLFFLA------AKTPG------RALALHALRSLEGETGGLPVRVLELVARDK 280
Query: 125 KCKYFENLKEKRDKVKEIVEFFLEN-PSYPWEVIE-----YSNLLEL------CPYEVTR 172
C++ + K + + + F E P+ +E + L E+ CPY + +
Sbjct: 281 ACEHPD--KACHGESCPLAQGFYERLPAARAAAVEARWLDQARLREVALAHRVCPYYLGQ 338
Query: 173 KVGEKANVIVASYLYMVNPWIRQAFLDGLG-LEYSDLIVIFDEAHNLPDQAISALSDRLS 231
++ ++ V Y Y + A L GL + + V+ DEAHNL ++ S L
Sbjct: 339 ELARWCDLAVGDYNYYFD---LGAMLHGLAQVNQWRVAVLVDEAHNLVERGRRMYSAELD 395
Query: 232 IRSVERAIKEANEYGEKDIENFLSIFLRGLEIIYKEKLENYEISEVPLSPASIFEHVSSI 291
K A E K +E R + K + ++Y+ + P
Sbjct: 396 QGDFLGVRKTAPEALRKPLERIQ----RAWNELGKTQADDYQAYDEP------------- 438
Query: 292 LGLRERDLLRFLQEMVEVGDAIREDKIERNLPPRSYVGRVGEFLWNWIS---LADRSDYL 348
++ LL + + D + E P++ + EF + + LA+
Sbjct: 439 ---PQKLLLALQNAVAAINDLLAEQ-------PQALEPALQEFYFAILQFGRLAELFGEH 488
Query: 349 HVFTREK-----GLALEIVALDPSVALEFLED----VHSAILMSGTLSPLEAFRDIIGVN 399
+F EK G +L + L V FL + S +L S TL P + + D++G+
Sbjct: 489 SLFDIEKRPGRNGRSLARLCLRNVVPAAFLAERFAASRSTVLFSATLGPRDYYADLLGLP 548
Query: 400 ARLK--KFPRMVKSENAIVLVARDVSTRGEERSPVLYKKLAEYIFEAVKIIPKNVGVFTA 457
A + +E V + R VSTR +R L +A + E + P N F +
Sbjct: 549 AGTPWLEVDSPFSAEQLEVHIQRRVSTRYAQRQASL-APIAAILGEQFRQRPGNYLAFFS 607
Query: 458 SYEVLEGLISTNVHIRIEEEIGKKVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMG 517
S++ L+ + + + + + +E + F A G G+ F V+G
Sbjct: 608 SFDYLQQALD----VFRQAYPWVPCWSQTPRMDEAERRVFLERFVA---GGEGIGFAVLG 660
Query: 518 GRNSEGQDYSGDEMNGVIL--VGIPYARPTPRVQAQIRYYEKKFPGKGRYYGYLLPAHRK 575
G EG D G+ + G + +G+P P V QIR ++ G G Y YL P +K
Sbjct: 661 GAFGEGIDLPGERLIGAFIATLGLPQVNP---VNEQIRLRMQRLFGDGYDYTYLYPGLQK 717
Query: 576 LAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDW 612
+ QAAGRV RS ++G + ++D R V+R LP W
Sbjct: 718 VVQAAGRVIRSRSDRGVVHLIDDRFAQAKVRRLLPGW 754
>gi|6325249 kinetochore protein in the DEAH box family; Chl1p [Saccharomyces
cerevisiae] >gi|116351|sp|P22516|CHL1_YEAST CHL1 PROTEIN
>gi|82952|pir||S12499 CHL1 protein - yeast
(Saccharomyces cerevisiae) >gi|3538|emb|CAA39922.1|
(X56584) CHL1 [Saccharomyces cerevisiae]
>gi|683782|emb|CAA88378.1| (Z48483) Chl1p [Saccharomyces
cerevisiae] >gi|965085|gb|AAB68097.1| (U33335) Chl1p
[Saccharomyces cerevisiae] >gi|1314068|emb|CAA95033.1|
(Z71255) Chl1p [Saccharomyces cerevisiae]
Length = 861
Score = 95.2 bits (233), Expect = 2e-18
Identities = 128/625 (20%), Positives = 254/625 (40%), Gaps = 86/625 (13%)
Query: 59 KVIYLARTHKQMDRVIEELK------RIREIA---KVSGIEFRSRKDLCLHSYIRTFAQ- 108
K+ Y +RT+ Q+ + +L+ R+ KV + S+K LC++ + +
Sbjct: 232 KIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTL 291
Query: 109 DAYTSMIVCKSLKRLGK-CKYFENLKEKRDKVKEIV--EFFLENPSYPWEVIEYSNLLEL 165
+A C L+ + C +++N E R + + +++ L +
Sbjct: 292 EAIND--ACADLRHSKEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGI 349
Query: 166 CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISA 225
CPY +R+ A V+ Y Y+++ R + L + + IVI DEAHNL + S
Sbjct: 350 CPYYASREALPIAEVVTLPYQYLLSESTRSS----LQINLENSIVIIDEAHNLIETINSI 405
Query: 226 LSDRLSIRSVERAIKEANEYGEK-----------DIENFLSIFLRGLEIIYKEKLENYEI 274
S ++S+ ++ K Y K ++ S+ + ++ I K N++
Sbjct: 406 YSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVK----NFKK 461
Query: 275 SEVPLSPASIFEHVSSILGLRERDLLRFLQ------EMVEVGDAIREDKIERNLPP---- 324
+ P +F S+I L LLR+++ ++ A++E++ +N P
Sbjct: 462 IGQEIDPNDMFTG-SNIDTLNIHKLLRYIKVSKIAYKIDTYNQALKEEESSKNENPIKET 520
Query: 325 -------RSYVGRVGEFLWNWISLADRSDYLHVFTREKGLALEIVALDPSVALE-FLEDV 376
+ + +V +FL+ +L + EK +++ + L+PS E L
Sbjct: 521 HKKSVSSQPLLFKVSQFLYCLTNLTSEGQFFF----EKNYSIKYMLLEPSKPFESILNQA 576
Query: 377 HSAILMSGTLSPLEAFR-----DIIGVNARLKKFPRMVKSENAIVLVARDVS---TRGEE 428
+L GT+ P+ F ++ + ++ EN + T +
Sbjct: 577 KCVVLAGGTMEPMSEFLSNLLPEVPSEDITTLSCNHVIPKENLQTYITNQPELEFTFEKR 636
Query: 429 RSPVLYKK-LAEYIFEAVKIIPKNVGV--FTASYEVLEGLIST---NVHIRIEEEIGKKV 482
SP L L ++ + K +PK G+ F SY+ L +I N + +K+
Sbjct: 637 MSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNV-RKI 695
Query: 483 FIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYA 542
F E +D +D L + A+G G +L ++GG+ SEG ++ D V++VG+P+
Sbjct: 696 FYEAKDG----DDILSGYSDSVAEGRGSLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFP 751
Query: 543 RP-TPRVQAQIRYYEKKFPGKGRYYGYLLPAHRK---------LAQAAGRVHRSEEEKGS 592
+ + + ++ K G A ++ + Q+ GR R + +
Sbjct: 752 NIFSGELIVKRKHLAAKIMKSGGTEEEASRATKEFMENICMKAVNQSVGRAIRHANDYAN 811
Query: 593 IVILDYRVLWNTVKRDLPDWMVETM 617
I +LD R ++ L W+ +++
Sbjct: 812 IYLLDVRYNRPNFRKKLSRWVQDSI 836
>emb|CAA22963.1| (AL035331) /prediction=(method:""genefinder"", version:""084"",
score:""114.88"")~/prediction=(method:""genscan"",
version:""1.0"", score:""280.47"")~/match=(desc:""CHL1
POTENTIAL HELICASE"", species:""HOMO SAPIENS (HUMAN)"",
ranges:(query:20397..20645> >gi|6018910|emb|CAB58099.1|
(AL121806) /prediction=(method:""genscan"",
version:""1.0"",
score:""280.47"")~/prediction=(method:""genefinder"",
version:""084"", score:""114.88"")~/match=(desc:""CHL1
POTENTIAL HELICASE"", species:""Homo sapiens (Human)"",
ranges:(query:130984..1312> >gi|7290134|gb|AAF45598.1|
(AE003420) EG:33C11.2 gene product [Drosophila
melanogaster]
Length = 861
Score = 93.2 bits (228), Expect = 8e-18
Identities = 140/658 (21%), Positives = 257/658 (38%), Gaps = 116/658 (17%)
Query: 59 KVIYLARTHKQMDRVIEELKRIREIAKVSGIEFRSRKDLCLHSYIRTFAQ-----DAYTS 113
++ + +RTH Q+ +++ EL++ V I SR+ LC + +R +
Sbjct: 189 QIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLD 248
Query: 114 MIVCKSLKRLGKCKYFENLKEKR------DKVKEIVEFFLENPSYPWEVIEYSNLLELCP 167
M K+ K R V+ + + L P E+ C
Sbjct: 249 MATKKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPLDIEELANEGTACGGCS 308
Query: 168 YEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLPDQAISALS 227
Y +R E A +I+ Y ++ R LG+ IVI DEAHNL D
Sbjct: 309 YYASRSAVEHAQLILLPYQLLLQKSARNQ----LGISLKGSIVIVDEAHNLLDSVAQLHG 364
Query: 228 DRLSIRSVERAIKEANEYGEK-----------DIENFLSIFLRGLEIIYKEK-------- 268
+S + +ERA + + Y + I + I R L+I+ + K
Sbjct: 365 SEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCS 424
Query: 269 -LENYEIS------------------------------------------EVPLSPAS-- 283
+ YE++ + P+S A
Sbjct: 425 MMRTYELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTARSL 484
Query: 284 IFEHVSSILGLRERDLLRFLQEMVEVGDAIREDKIE----RNLPPRSYVGRVGE-----F 334
I + ++S L+E+ + ++ VE D +EDK E + P + V V
Sbjct: 485 ILQRLASEQKLKEKT--KSVKRRVE--DINKEDKAEELQEQQKPTKKPVEEVAPSPIRPL 540
Query: 335 LWNWISLADRSDYLHVFTREKGLALEIVALDPSVAL-EFLEDVHSAILMSGTLSPLEAFR 393
L +L ++ + G L+ + LDP+ + + + + ++ GT+ P + +
Sbjct: 541 LAFLETLTSNAEDGRILVDPVGGTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKELK 600
Query: 394 DII--GVNARL-KKFPRMVKSENAIVLVARDVSTRGEERSPVLYK-----------KLAE 439
+ + G + RL ++F V + +AI+ V + G +P+ +K +L+
Sbjct: 601 EQLFTGCHDRLVERFYNHVVANDAILPF---VISNGPSGAPLSFKFAHRGSAEMLRELSM 657
Query: 440 YIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIG--KKVFIEKRDASSSENDAL 497
+ +++P V F SYE L+ + E I K VF E ++ D
Sbjct: 658 ILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAEQLLDNY 717
Query: 498 VAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVGIPYARP-TPRVQAQIRYYE 556
K A G +L V+GG+ SEG +++ D V++VG+PY+ +P ++ ++++ +
Sbjct: 718 ALAIKRPAS-YGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLD 776
Query: 557 KKF-PGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPDWM 613
+K PG G Y Y + + Q GR R ++ + +LD R ++ LP W+
Sbjct: 777 EKLGPGAGNEY-YENLCVKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWI 833
>gb|AAC72116.1| (AC005278) Strong similarity to gb|U04968 nucleotide excision
repair protein (ERCC2) from Cricetulus grisseus.
[Arabidopsis thaliana]
Length = 735
Score = 90.5 bits (221), Expect = 5e-17
Identities = 77/265 (29%), Positives = 130/265 (49%), Gaps = 34/265 (12%)
Query: 4 YFPYKTLRPHQDEF-IELVRDVVKRGEKVIIEAPTGFGKTISVLAGVLPHAIS---FGYK 59
YFPY + P Q E+ +EL R + +G ++E PTG GKTI++L+ + + +S K
Sbjct: 11 YFPYDNIYPEQYEYMVELKRALDAKGH-CLLEMPTGTGKTIALLSLITSYRLSRPDSPIK 69
Query: 60 VIYLARTHKQMDRVIEELKRIREI--------AKVSGIEFRSRKDLCLHSYIRTFAQDAY 111
++Y RT +M++ + ELK + + AK+ + SRK+LC+++ + A++
Sbjct: 70 LVYCTRTVHEMEKTLGELKLLHDYQVRHLGTQAKILALGLSSRKNLCVNTKVLA-AENRD 128
Query: 112 TSMIVCKSLKRLGKCKYFENLKEKRDKVKEIVEFF------LENPSYPWEVIEYSNLLEL 165
+ C R + L + V E+ +FF EN P V +L
Sbjct: 129 SVDAAC----RKRTASWVRALSTENPNV-ELCDFFENYEKAAENALLPPGVYTLEDLRAF 183
Query: 166 ------CPYEVTRKVGEKANVIVASYLYMVNPWIRQAFLDGLGLEYSDLIVIFDEAHNLP 219
CPY + R + + ANVIV SY Y+++P + L + +V+FDEAHN+
Sbjct: 184 GKNRGWCPYFLARHMIQFANVIVYSYQYLLDPKVAGFISKEL---QKESVVVFDEAHNID 240
Query: 220 DQAISALSDRLSIRSVERAIKEANE 244
+ I ALS + ++E A + N+
Sbjct: 241 NVCIEALSVSVRRVTLEGANRNLNK 265
Score = 87.8 bits (214), Expect = 3e-16
Identities = 76/281 (27%), Positives = 134/281 (47%), Gaps = 20/281 (7%)
Query: 359 LEIVALDPSVALEFLED-VHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVL 417
L++ D S+A++ + D S ++ SGTLSP++ + ++ + + +M + + I
Sbjct: 446 LQLSCHDASLAIKPVFDRFQSVVITSGTLSPIDLYPRLLNFTPVVSRSFKMSMTRDCICP 505
Query: 418 VARDVSTRGEERSPV-----------LYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLI 466
+ V TRG ++ PV + + + + E V I+P V F SY ++G+I
Sbjct: 506 M---VLTRGSDQLPVSTKFDMRSDPGVVRNYGKLLVEMVSIVPDGVVCFFVSYSYMDGII 562
Query: 467 STNVHIRIEEEI--GKKVFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQ 524
+T I +EI K VFIE +D + AL +A G G V F V G+ +EG
Sbjct: 563 ATWNETGILKEIMQQKLVFIETQDVVETTL-ALDNYRRACDCGRGAVFFSVARGKVAEGI 621
Query: 525 DYSGDEMNGVILVGIPYARPTPRV-QAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRV 583
D+ V++ G+P+ ++ +A++ Y F K + A R+ AQ GRV
Sbjct: 622 DFDRHYGRLVVMYGVPFQYTLSKILRARLEYLHDTFQIKEGDF-LTFDALRQAAQCVGRV 680
Query: 584 HRSEEEKGSIVILDYRVLWNTVKRDLPDWMVETMQPVTLPL 624
RS+ + G ++ D R + + LP W++ ++ L L
Sbjct: 681 IRSKADYGMMIFADKRYSRHDKRSKLPGWILSHLRDAHLNL 721
>pir||T45294 hypothetical protein KIAA1088 [imported] - human (fragment)
>gi|5689513|dbj|BAA83040.1| (AB029011) KIAA1088 protein
[Homo sapiens]
Length = 1161
Score = 79.6 bits (193), Expect = 1e-13
Identities = 78/302 (25%), Positives = 131/302 (42%), Gaps = 38/302 (12%)
Query: 342 ADRSD-YLHVFTREKGLALEIVALDPSVALEFL--EDVHSAILMSGTLSPLEAFRDIIGV 398
A RSD + R++G L P ++ L + V S IL SGTL+P+ +F
Sbjct: 196 AQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSF------ 249
Query: 399 NARLKKFPRMVKSENAIVLVARDV-------STRGEERSPVLYKKLAEYIFEAV------ 445
A + P V EN ++ + G + S ++ +E ++
Sbjct: 250 -ALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGN 308
Query: 446 --KIIPKNVGVFTASYEVLEGLIS--TNVHIRIEEEIGKKVFIEKRDASSSENDALVAEF 501
+++P + +F SY V+E + + + E K +F+E R S
Sbjct: 309 IARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYA 368
Query: 502 KAEAKGNGGVLF-GVMGGRNSEGQDYSGDEMNGVILVGIPYA-RPTPRVQAQIRYYEKKF 559
+ A G+ G F V G+ SEG D+S GVI+ G+PY R PRV ++++ ++
Sbjct: 369 RVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDE-M 427
Query: 560 PGKGRYYGYLLP--------AHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPD 611
G+G G L A R + QA GRV R ++ G++ + D+R + + LP
Sbjct: 428 KGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPS 487
Query: 612 WM 613
W+
Sbjct: 488 WV 489
>gi|7706541 helicase-like protein NHL [Homo sapiens]
>gi|11420403|ref|XP_009441.1| helicase-like protein NHL
[Homo sapiens] >gi|6969265|gb|AAF33687.1|AF217795_1
(AF217795) helicase-like protein NHL [Homo sapiens]
>gi|11190529|emb|CAC16223.1| (AL353715) bK3184A7.3.1
(helicase-like protein NHL) [Homo sapiens]
Length = 1219
Score = 79.6 bits (193), Expect = 1e-13
Identities = 78/302 (25%), Positives = 131/302 (42%), Gaps = 38/302 (12%)
Query: 342 ADRSD-YLHVFTREKGLALEIVALDPSVALEFL--EDVHSAILMSGTLSPLEAFRDIIGV 398
A RSD + R++G L P ++ L + V S IL SGTL+P+ +F
Sbjct: 435 AQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSF------ 488
Query: 399 NARLKKFPRMVKSENAIVLVARDV-------STRGEERSPVLYKKLAEYIFEAV------ 445
A + P V EN ++ + G + S ++ +E ++
Sbjct: 489 -ALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGN 547
Query: 446 --KIIPKNVGVFTASYEVLEGLIS--TNVHIRIEEEIGKKVFIEKRDASSSENDALVAEF 501
+++P + +F SY V+E + + + E K +F+E R S
Sbjct: 548 IARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYA 607
Query: 502 KAEAKGNGGVLF-GVMGGRNSEGQDYSGDEMNGVILVGIPYA-RPTPRVQAQIRYYEKKF 559
+ A G+ G F V G+ SEG D+S GVI+ G+PY R PRV ++++ ++
Sbjct: 608 RVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDE-M 666
Query: 560 PGKGRYYGYLLP--------AHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPD 611
G+G G L A R + QA GRV R ++ G++ + D+R + + LP
Sbjct: 667 KGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPS 726
Query: 612 WM 613
W+
Sbjct: 727 WV 728
Score = 75.3 bits (182), Expect = 2e-12
Identities = 65/260 (25%), Positives = 119/260 (45%), Gaps = 60/260 (23%)
Query: 2 FEYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLA-----------GVL 50
F + PYK Q E++ V + +++ I+E+PTG GKT+ +L G+
Sbjct: 13 FPFQPYKC----QQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGIS 68
Query: 51 PHAI---------------SFGY----------------KVIYLARTHKQMDRVIEELKR 79
I S+G K+IY +RTH Q+ +VI EL+
Sbjct: 69 ARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRN 128
Query: 80 IREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSLKRLGKCKYFENLKEKRDKV 139
KV + SR+ LC+H ++ + + + +C+ C ++ N++EK
Sbjct: 129 TSYRPKVCVL--GSREQLCIHPEVKK-QESNHLQIHLCRKKVASRSCHFYNNVEEKS--- 182
Query: 140 KEIVEFFLENPSYPWE-VIEYSNLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFL 198
+E L +P E +++ + +CPY ++R + ++A++I Y Y+++ R+A
Sbjct: 183 ---LEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAH- 238
Query: 199 DGLGLEYSDLIVIFDEAHNL 218
++ +VIFDEAHN+
Sbjct: 239 ---NIDLKGTVVIFDEAHNV 255
>gb|AAF35243.1| (AF217796) helicase-like protein NHL [Homo sapiens]
Length = 1400
Score = 79.6 bits (193), Expect = 1e-13
Identities = 78/302 (25%), Positives = 131/302 (42%), Gaps = 38/302 (12%)
Query: 342 ADRSD-YLHVFTREKGLALEIVALDPSVALEFL--EDVHSAILMSGTLSPLEAFRDIIGV 398
A RSD + R++G L P ++ L + V S IL SGTL+P+ +F
Sbjct: 435 AQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSF------ 488
Query: 399 NARLKKFPRMVKSENAIVLVARDV-------STRGEERSPVLYKKLAEYIFEAV------ 445
A + P V EN ++ + G + S ++ +E ++
Sbjct: 489 -ALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGN 547
Query: 446 --KIIPKNVGVFTASYEVLEGLIS--TNVHIRIEEEIGKKVFIEKRDASSSENDALVAEF 501
+++P + +F SY V+E + + + E K +F+E R S
Sbjct: 548 IARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYA 607
Query: 502 KAEAKGNGGVLF-GVMGGRNSEGQDYSGDEMNGVILVGIPYA-RPTPRVQAQIRYYEKKF 559
+ A G+ G F V G+ SEG D+S GVI+ G+PY R PRV ++++ ++
Sbjct: 608 RVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDE-M 666
Query: 560 PGKGRYYGYLLP--------AHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPD 611
G+G G L A R + QA GRV R ++ G++ + D+R + + LP
Sbjct: 667 KGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPS 726
Query: 612 WM 613
W+
Sbjct: 727 WV 728
Score = 75.3 bits (182), Expect = 2e-12
Identities = 65/260 (25%), Positives = 119/260 (45%), Gaps = 60/260 (23%)
Query: 2 FEYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVLA-----------GVL 50
F + PYK Q E++ V + +++ I+E+PTG GKT+ +L G+
Sbjct: 13 FPFQPYKC----QQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGIS 68
Query: 51 PHAI---------------SFGY----------------KVIYLARTHKQMDRVIEELKR 79
I S+G K+IY +RTH Q+ +VI EL+
Sbjct: 69 ARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRN 128
Query: 80 IREIAKVSGIEFRSRKDLCLHSYIRTFAQDAYTSMIVCKSLKRLGKCKYFENLKEKRDKV 139
KV + SR+ LC+H ++ + + + +C+ C ++ N++EK
Sbjct: 129 TSYRPKVCVL--GSREQLCIHPEVKK-QESNHLQIHLCRKKVASRSCHFYNNVEEKS--- 182
Query: 140 KEIVEFFLENPSYPWE-VIEYSNLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQAFL 198
+E L +P E +++ + +CPY ++R + ++A++I Y Y+++ R+A
Sbjct: 183 ---LEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAH- 238
Query: 199 DGLGLEYSDLIVIFDEAHNL 218
++ +VIFDEAHN+
Sbjct: 239 ---NIDLKGTVVIFDEAHNV 255
>gb|AAF59650.1| (AC024801) contains similarity to TR:Q91941 [Caenorhabditis
elegans]
Length = 667
Score = 79.6 bits (193), Expect = 1e-13
Identities = 65/201 (32%), Positives = 95/201 (46%), Gaps = 15/201 (7%)
Query: 422 VSTRGEERSPV-LYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIRIEEEIGK 480
+++R E+R+ V + + + E ++P + VF SY +E +I I +E+ K
Sbjct: 22 MTSRFEQRADVAVIRNYGNLVLEMASLVPDGMVVFFTSYLYMENVIGVWYEQHIIDELMK 81
Query: 481 K--VFIEKRDASSSENDALVAEFKAEAKGNGGVLFGVMGGRNSEGQDYSGDEMNGVILVG 538
+FIE DA + + AL +A G G VLF V G+ SEG D+S VI++G
Sbjct: 82 YKLLFIETNDALET-SAALEKYVEACDSGRGAVLFSVARGKVSEGIDFSHHLGRCVIMLG 140
Query: 539 IPYARPTPRVQAQIRYYEKKFPGKGRYYGYLLPAHRKLAQAAGRVHRSEEEKGSIVILDY 598
IPY RV +R E F A R AQ GR RS+ + G +V D
Sbjct: 141 IPYMYTESRV---LRARENDF--------LTFDAMRHTAQCMGRALRSKTDYGLMVFADK 189
Query: 599 RVLWNTVKRDLPDWMVETMQP 619
R N + LP WM E ++P
Sbjct: 190 RFSRNDKRGKLPRWMQEYLEP 210
>emb|CAC16224.1| (AL353715) bK3184A7.3.2 (KIAA1088) [Homo sapiens]
Length = 1060
Score = 79.6 bits (193), Expect = 1e-13
Identities = 78/302 (25%), Positives = 131/302 (42%), Gaps = 38/302 (12%)
Query: 342 ADRSD-YLHVFTREKGLALEIVALDPSVALEFL--EDVHSAILMSGTLSPLEAFRDIIGV 398
A RSD + R++G L P ++ L + V S IL SGTL+P+ +F
Sbjct: 196 AQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSF------ 249
Query: 399 NARLKKFPRMVKSENAIVLVARDV-------STRGEERSPVLYKKLAEYIFEAV------ 445
A + P V EN ++ + G + S ++ +E ++
Sbjct: 250 -ALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGN 308
Query: 446 --KIIPKNVGVFTASYEVLEGLIS--TNVHIRIEEEIGKKVFIEKRDASSSENDALVAEF 501
+++P + +F SY V+E + + + E K +F+E R S
Sbjct: 309 IARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYA 368
Query: 502 KAEAKGNGGVLF-GVMGGRNSEGQDYSGDEMNGVILVGIPYA-RPTPRVQAQIRYYEKKF 559
+ A G+ G F V G+ SEG D+S GVI+ G+PY R PRV ++++ ++
Sbjct: 369 RVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDE-M 427
Query: 560 PGKGRYYGYLLP--------AHRKLAQAAGRVHRSEEEKGSIVILDYRVLWNTVKRDLPD 611
G+G G L A R + QA GRV R ++ G++ + D+R + + LP
Sbjct: 428 KGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPS 487
Query: 612 WM 613
W+
Sbjct: 488 WV 489
>gb|AAF46074.1| (AE003435) CG4078 gene product [Drosophila melanogaster]
Length = 985
Score = 79.6 bits (193), Expect = 1e-13
Identities = 74/304 (24%), Positives = 129/304 (42%), Gaps = 70/304 (23%)
Query: 2 FEYFPYKTLRPHQDEFIELVRDVVKRGEKVIIEAPTGFGKTISVL--------------- 46
F + PY R + ++ I +RD G ++E+PTG GKT+S+L
Sbjct: 13 FPFEPYPVQRAYMEKVIHCLRD----GTNGVLESPTGTGKTLSLLCSSLAWIRTRQSEHQ 68
Query: 47 --------------------------AGVLPHAISFGY-KVIYLARTHKQMDRVIEELKR 79
A + A ++G KVIY +RTH Q+ + + ELKR
Sbjct: 69 KQMVKMEKADFSGLGGGAPGGDLSELAKTMGRANNWGVPKVIYASRTHSQLTQAMRELKR 128
Query: 80 IREIAKVSGIEFRSRKDLCLHSYI-RTFAQDAYTSMIVCKSLKRLGKCKYFENLKEKRDK 138
A + + SR LC+H + R T+M CK C + ++ ++D
Sbjct: 129 TA-YANMRSVVLGSRDQLCIHPEVMREQGNSNKTNM--CKLRVHSKTCSFQMRVESRKDH 185
Query: 139 VKEIVEFFLENPSYP--WEVIEYSNLLELCPYEVTRKVGEKANVIVASYLYMVNPWIRQA 196
L P+ ++++ L++CPY +R++ +A++ Y Y+++P R+A
Sbjct: 186 PD------LRGPTIMDIEDLVKVGQRLKICPYFASRELVPQADITFMPYNYLLDPKARKA 239
Query: 197 FLDGLGLEYSDLIVIFDEAHNLPDQAISALSDRLSIRSVERAIKEANEYGEKDIENFLSI 256
+E + IVI DEAHN+ + S ++ V AI +D+ + + +
Sbjct: 240 ----NKIELGNTIVILDEAHNIEKICEESASVQIKSSDVAMAI--------EDVTHIMQV 287
Query: 257 FLRG 260
F G
Sbjct: 288 FASG 291
>pir||T21711 hypothetical protein F33H2.1 - Caenorhabditis elegans
>gi|3876642|emb|CAB04262.1| (Z81526) predicted using
Genefinder~cDNA EST yk39f5.3 comes from this gene~cDNA
EST yk39f5.5 comes from this gene~cDNA EST yk185a6.5
comes from this gene~cDNA EST yk160h7.5 comes from this
gene~cDNA EST yk160h7.3 comes from this gene~cDNA EST
yk224f7.3>
Length = 983
Score = 74.9 bits (181), Expect = 3e-12
Identities = 68/259 (26%), Positives = 112/259 (42%), Gaps = 25/259 (9%)
Query: 367 SVALEFLE---DVHSAILMSGTLSPLEAFRDIIGVNARLKKFPRMVKSENAIVLVARDVS 423
S AL F + + S +L SGTL P++ + +G+ + + V +++ I +
Sbjct: 668 SPALSFFDAFNETRSIVLASGTLCPMDTLKTELGMEFKQQVEGDQVINKDNIFAAVLPIG 727
Query: 424 TRGE----------ERSPVLYKKLAEYIFEAVKIIPKNVGVFTASYEVLEGLISTNVHIR 473
G + Y +L I +P + F SY VL+ L +
Sbjct: 728 PFGNRIQCTYRNTSDPESSFYCELGAIIKYVCSNVPAGILCFLPSYRVLDQLKQCMIRNS 787
Query: 474 IEEEIGKKVFIEKRDASSSENDALVAEFKAE--------AKGNGGVLFGVMGGRNSEGQD 525
+I K + SSE +++ +F A A NG ++F V G+ SEG D
Sbjct: 788 TMRQIEMKKVVLYEPRRSSELTSVMDQFDAAIFDPSRFGANINGSLMFAVFRGKVSEGID 847
Query: 526 YSGDEMNGVILVGIPYARP-TPRVQAQIRYYEKKFPGKGRYYG---YLLPAHRKLAQAAG 581
++ D VI VGIPY +V A+ Y ++ KG G Y A+R L QA G
Sbjct: 848 FADDRARVVISVGIPYPNAMDDQVNAKKLYNDQNSKEKGILTGDEWYTTQAYRALNQALG 907
Query: 582 RVHRSEEEKGSIVILDYRV 600
R R + + G+++++D R+
Sbjct: 908 RCLRHKNDWGAMLMIDERL 926
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.140 0.401
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 228973106
Number of Sequences: 2977
Number of extensions: 9750674
Number of successful extensions: 27865
Number of sequences better than 1.0e-10: 34
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 27677
Number of HSP's gapped (non-prelim): 79
length of query: 637
length of database: 189,106,746
effective HSP length: 58
effective length of query: 579
effective length of database: 154,394,500
effective search space: 89394415500
effective search space used: 89394415500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 168 (69.9 bits)