BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2388 (PAB2388) DE:DIPEPTIDASE
(307 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75070 dipeptidase PAB2388 - Pyrococcus abyssi (strain Orsa... 618 e-176
pir||E71095 probable membrane dipeptidase - Pyrococcus horikoshi... 553 e-156
gb|AAF97793.1|AF268476_1 (AF268476) thermostable dipeptidase Bdp... 167 1e-40
dbj|BAB05990.1| (AP001515) dipeptidase [Bacillus halodurans] 158 9e-38
emb|CAA63656.1| (X93169) orfD [Listeria monocytogenes] 144 1e-33
pir||JC4222 membrane dipeptidase (EC 3.4.13.19) homolog - Acinet... 139 3e-32
gb|AAF56581.1| (AE003755) CG6154 gene product [Drosophila melano... 134 2e-30
dbj|BAA02431.1| (D13138) dipeptidase precursor [Homo sapiens] 133 3e-30
sp|P16444|MDP1_HUMAN MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEH... 129 6e-29
gi|4758190 dipeptidase 1 (renal) [Homo sapiens] >gi|598189|gb|AA... 129 6e-29
gi|11641269 putative dipeptidase [Homo sapiens] >gi|11071729|emb... 128 7e-29
sp|P31430|MDP1_RAT MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEHYD... 126 3e-28
gb|AAA41094.1| (L07315) dipeptidase [Rattus norvegicus] >gi|4599... 126 3e-28
gb|AAF49997.1| (AE003543) CG5917 gene product [Drosophila melano... 125 5e-28
pir||T41665 probable dipeptidase - fission yeast (Schizosaccharo... 125 6e-28
pir||S33757 membrane dipeptidase (EC 3.4.13.19) precursor - mouse 125 8e-28
sp|P43477|MDP1_SHEEP MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEH... 125 8e-28
gi|6681217 dipeptidase 1 (renal) [Mus musculus] >gi|400238|sp|P3... 124 1e-27
sp|P31429|MDP1_RABIT MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEH... 124 1e-27
sp|P22412|MDP1_PIG MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEHYD... 124 1e-27
pir||T01637 gene R protein - Acinetobacter calcoaceticus (fragme... 120 2e-26
sp|P07783|YPQR_ACICA HYPOTHETICAL PROTEIN IN PQQ-III 3'REGION (O... 120 2e-26
pir||H72724 probable microsomal dipeptidase APE0337 - Aeropyrum ... 119 5e-26
sp|P27509|YPQQ_KLEPN HYPOTHETICAL PROTEIN IN PQQA 5'REGION (ORF ... 117 2e-25
pir||T11632 membrane dipeptidase (EC 3.4.13.19) - fission yeast ... 115 5e-25
pir||D82971 hypothetical protein PA5396 [imported] - Pseudomonas... 113 4e-24
pir||B71089 hypothetical protein PH0975 - Pyrococcus horikoshii ... 112 5e-24
gi|11641273 putative metallopeptidase (family M19) [Homo sapiens... 111 8e-24
gb|AAK42051.1| Microsomal dipeptidase [Sulfolobus solfataricus] 105 8e-22
gi|11431942 dipeptidase 1 (renal) [Homo sapiens] 87 3e-16
gb|AAF53657.1| (AE003658) CG7198 gene product [Drosophila melano... 84 2e-15
pir||C71552 probable dipeptidase - Chlamydia trachomatis (seroty... 80 3e-14
pir||H81704 dipeptidase, probable TC0415 [imported] - Chlamydia ... 78 1e-13
pir||B72098 dipeptidase, probable CP0490 [imported] - Chlamydoph... 77 2e-13
pir||C75406 probable peptidase - Deinococcus radiodurans (strain... 77 3e-13
pir||C83347 probable dipeptidase precursor PA2393 [imported] - P... 75 8e-13
>pir||D75070 dipeptidase PAB2388 - Pyrococcus abyssi (strain Orsay)
>gi|5458377|emb|CAB49865.1| (AJ248286) DIPEPTIDASE
[Pyrococcus abyssi]
Length = 307
Score = 618 bits (1577), Expect = e-176
Identities = 307/307 (100%), Positives = 307/307 (100%)
Query: 1 MIFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTGISARVMSVWSRPDKRPVILRYALEA 60
MIFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTGISARVMSVWSRPDKRPVILRYALEA
Sbjct: 1 MIFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTGISARVMSVWSRPDKRPVILRYALEA 60
Query: 61 YNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIESLDILEIFHSMGLRV 120
YNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIESLDILEIFHSMGLRV
Sbjct: 61 YNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIESLDILEIFHSMGLRV 120
Query: 121 LTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAF 180
LTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAF
Sbjct: 121 LTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAF 180
Query: 181 PVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEKPTLEKYVRHIEYM 240
PVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEKPTLEKYVRHIEYM
Sbjct: 181 PVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEKPTLEKYVRHIEYM 240
Query: 241 VDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDTLNEKFSEKEVKAIAFENFKR 300
VDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDTLNEKFSEKEVKAIAFENFKR
Sbjct: 241 VDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDTLNEKFSEKEVKAIAFENFKR 300
Query: 301 VFERVVG 307
VFERVVG
Sbjct: 301 VFERVVG 307
>pir||E71095 probable membrane dipeptidase - Pyrococcus horikoshii
>gi|3257440|dbj|BAA30123.1| (AP000004) 320aa long
hypothetical membrane dipeptidase [Pyrococcus
horikoshii]
Length = 320
Score = 553 bits (1409), Expect = e-156
Identities = 272/309 (88%), Positives = 290/309 (93%), Gaps = 2/309 (0%)
Query: 1 MIFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTGISARVMSVWSRPDKRPVILRYALEA 60
MIFDAHSDLPT+VY EREKG+TRVLESNFEKFFTGISARVMSVWSRP+K+P+ILRYALEA
Sbjct: 12 MIFDAHSDLPTYVYEEREKGRTRVLESNFEKFFTGISARVMSVWSRPEKKPIILRYALEA 71
Query: 61 YNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIESLDILEIFHSMGLRV 120
YNRLFKDVSESE+ IVGTVKEM++AIK+GKVALWLGMEGGEPIESLDILEIFHS+GLRV
Sbjct: 72 YNRLFKDVSESEKLVIVGTVKEMEDAIKDGKVALWLGMEGGEPIESLDILEIFHSIGLRV 131
Query: 121 LTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAF 180
LTLTWSLRNQIGDGVFERT+GGLTNFGAEVVGKCEELGII+D+SHINEQGFWDVLDIT F
Sbjct: 132 LTLTWSLRNQIGDGVFERTRGGLTNFGAEVVGKCEELGIIIDLSHINEQGFWDVLDITGF 191
Query: 181 PVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEKPTLEKYVRHIEYM 240
PVIASHSNAK+LCD+ RNLTD+QIKAIAERDGVIGAVAIP FVDK+ PTLEKYV+HIEYM
Sbjct: 192 PVIASHSNAKSLCDNPRNLTDEQIKAIAERDGVIGAVAIPAFVDKDNPTLEKYVKHIEYM 251
Query: 241 VDLVGYKHVGIGLDFVYYL--GSKKSVEGLEDESKIPALIDTLNEKFSEKEVKAIAFENF 298
VDLVGYKHVGIG DFVYYL S KSVEGLEDESKIP LI L E FSEKEVK I FENF
Sbjct: 252 VDLVGYKHVGIGFDFVYYLPGWSGKSVEGLEDESKIPDLIKALEENFSEKEVKGITFENF 311
Query: 299 KRVFERVVG 307
KRVFERVVG
Sbjct: 312 KRVFERVVG 320
>gb|AAF97793.1|AF268476_1 (AF268476) thermostable dipeptidase Bdp [Brevibacillus
borstelensis]
Length = 307
Score = 167 bits (419), Expect = 1e-40
Identities = 104/304 (34%), Positives = 166/304 (54%), Gaps = 12/304 (3%)
Query: 2 IFDAHSDLPTFVYNEREKGKTR---VLESNFEKFFTG-ISARVMSVWSRPD-KRPVILRY 56
I D H D ++ +E R L +N E+ G + + +++ P K +
Sbjct: 3 IIDFHCDALYKMWKSKEPLSFRDSAELHTNLERLKQGRVKLQCFALYVPPQLKSEQQFQA 62
Query: 57 ALEAYNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPI-ESLDILEIFHS 115
L+ + +++V + + V ++D + +G++ L +EG + I L L I
Sbjct: 63 VLDQIDYFYEEVLKQPEMKHVKEWADLD-TLGDGEIGAMLTLEGVDAIGNDLKKLRILFQ 121
Query: 116 MGLRVLTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVL 175
+G+R + LTW+ N DG E+ GLT FG E+V E ++ DVSH+ EQ FWDV+
Sbjct: 122 LGVRSVGLTWNFANLAADGALEKRNAGLTAFGKEIVRLNNEHKVLTDVSHLCEQSFWDVM 181
Query: 176 DITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDK-EKPTLEKYV 234
++ +P IASHSNA+A+CDH RNL D+Q KA+ ++ G+I V P FV K + T++ +
Sbjct: 182 ELADYP-IASHSNARAICDHPRNLYDEQAKAMFDKGGMIHIVYYPHFVKKGGQATIDDLI 240
Query: 235 RHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDTLNEKFSEKEVKAIA 294
RHI++ L G + +G+G DF G + VEGLE I L++ L +++SE EV+ A
Sbjct: 241 RHIDHFCSLGGVRQIGLGSDFD---GIESFVEGLEHAGMIDNLLNELLKRYSESEVRGFA 297
Query: 295 FENF 298
ENF
Sbjct: 298 SENF 301
>dbj|BAB05990.1| (AP001515) dipeptidase [Bacillus halodurans]
Length = 310
Score = 158 bits (395), Expect = 9e-38
Identities = 104/307 (33%), Positives = 167/307 (53%), Gaps = 18/307 (5%)
Query: 2 IFDAHSDLPTFVYNE--REKGKTRVLESNFEKFFTG-ISARVMSVWSRPD-----KRPVI 53
IFDAH D ++ + RE +E+N + G + A+ +++ P+ K V
Sbjct: 3 IFDAHCDALLKLWEDPAREYTDDPAIEANAVRLMEGGVRAQCFAIFVGPNIPFDQKFQVA 62
Query: 54 LRYALEAYNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPI-ESLDILEI 112
L+ A + ++ K + +F + ++ + ++ L +EG +P + L+
Sbjct: 63 LQQAELFHEKILK---KHPQFSFIERWDDL-LTLDADQIGAILTLEGADPFGDDPTKLKT 118
Query: 113 FHSMGLRVLTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFW 172
+ +G+R L LTW+ N DGV E GGLT +G VV E ++ DVSH++E+GFW
Sbjct: 119 LYRLGVRSLGLTWNQANLCADGVGEPRGGGLTEWGKAVVSLNNEHHVLTDVSHLSERGFW 178
Query: 173 DVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFV-DKEKPTLE 231
DV++ FPV A+HSNAKA+C H RNLTD Q+KA+ E G IG V P F+ + +++
Sbjct: 179 DVIEYAQFPV-ATHSNAKAICKHRRNLTDAQLKALIEAGGFIGIVFHPHFLTGTDDASID 237
Query: 232 KYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDTLNEKFSEKEVK 291
++HIE++ L G KHVG G DF G V+GLE + +D L +++ E+ V+
Sbjct: 238 DVMKHIEHICSLGGQKHVGFGSDFD---GIPCFVDGLEHAGRFQWFMDELLKRYDEELVR 294
Query: 292 AIAFENF 298
A++NF
Sbjct: 295 GFAWDNF 301
>emb|CAA63656.1| (X93169) orfD [Listeria monocytogenes]
Length = 258
Score = 144 bits (359), Expect = 1e-33
Identities = 82/216 (37%), Positives = 122/216 (55%), Gaps = 6/216 (2%)
Query: 85 EAIKEGKVALWLGMEGGEPI-ESLDILEIFHSMGLRVLTLTWSLRNQIGDGVFERTKGGL 143
E + E K+ L +EG EPI LD L G+ + LTW+ N DG+ E GL
Sbjct: 41 ENLPEDKIGAMLTLEGIEPIGRDLDKLTQLLDGGVLSVGLTWNNANLAADGIMEERGAGL 100
Query: 144 TNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQ 203
T FG +++ E + DVSH++ + FW+ L+ F VIASHS+AKA+C H RNL D+Q
Sbjct: 101 TRFGKDIIHLLNERKVFTDVSHLSVKAFWETLEQAEF-VIASHSSAKAICAHPRNLDDEQ 159
Query: 204 IKAIAERDGVIGAVAIPEFVDKE-KPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSK 262
IKA+ E D +I + P F + +E +RHI+++ +L G K++G G DF G
Sbjct: 160 IKAMIEHDAMIHVIFHPLFTTNDGVADIEDVIRHIDHICELGGMKNIGFGSDFD---GIP 216
Query: 263 KSVEGLEDESKIPALIDTLNEKFSEKEVKAIAFENF 298
V+GLE K ++TL + ++++EV+ A NF
Sbjct: 217 DHVKGLEHAGKYQNFLETLGKHYTKEEVEGFASRNF 252
>pir||JC4222 membrane dipeptidase (EC 3.4.13.19) homolog - Acinetobacter
calcoaceticus >gi|1088400|dbj|BAA08867.1| (D50330) acdp
[Acinetobacter calcoaceticus] >gi|1582793|prf||2119304A
dipeptidase [Acinetobacter calcoaceticus]
Length = 350
Score = 139 bits (348), Expect = 3e-32
Identities = 82/268 (30%), Positives = 145/268 (53%), Gaps = 17/268 (6%)
Query: 53 ILRYALEAYNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIE-SLDILE 111
I + LE + + S +I +V+++ + K+ + L MEG E ++ + D+L+
Sbjct: 86 IEQICLEQLDIAHQLAQRSTDIQICTSVQDIQSCVNTQKLGIVLHMEGAEALQQNSDLLD 145
Query: 112 IFHSMGLRVLTLTWSLRNQIGDGVFER------TKGGLTNFGAEVVGKCEELGIIVDVSH 165
+F+ GLR + W+ + G G+ + T GLT G + +C + +++DVSH
Sbjct: 146 VFYDRGLRSIGPLWNRPSLFGHGLNAKFPHSPDTGAGLTQDGKAFIKRCADKKMVIDVSH 205
Query: 166 INEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDK 225
+NEQ FWD +D+ P++A+HSNA ALC RNLTD Q+KAI E G++G F+
Sbjct: 206 MNEQAFWDTVDLLQQPIVATHSNAHALCPQARNLTDQQLKAIRESKGIVGVNFDVAFLRS 265
Query: 226 E-----KPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDT 280
+ +++ + H++Y++D +G +HV G DF G+ E LED + LI
Sbjct: 266 DGQRNANTSIDVILDHLDYLLDRLGEEHVAFGSDFD---GALIGTE-LEDVMGLHKLIHR 321
Query: 281 LNEK-FSEKEVKAIAFENFKRVFERVVG 307
+ ++ +S + ++ + F N+ V R++G
Sbjct: 322 MQQRAYSSELIEKLCFTNWINVLYRILG 349
>gb|AAF56581.1| (AE003755) CG6154 gene product [Drosophila melanogaster]
Length = 404
Score = 134 bits (333), Expect = 2e-30
Identities = 107/337 (31%), Positives = 164/337 (47%), Gaps = 39/337 (11%)
Query: 2 IFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTGISARVMSVWSRPDKRPVI-------- 53
+ D H+DLP +N R+ K ++ + +F ++ S WS D R +
Sbjct: 67 LIDGHNDLP---WNIRKFLKNQLKDFHFGGDLRELAPWSSSAWSHTDLRRLKEGMVSAQF 123
Query: 54 -LRYA------LEAYNRLFKDVSESERF--------RIVGTVKEMDEAIKEGKVALWLGM 98
YA L+A + + R +V T +++ + GK+A +G+
Sbjct: 124 WSAYAPCSSQHLDAVQLTLEQIDLIRRLVQLYPHHMALVTTASGIEQTHRTGKIASLIGV 183
Query: 99 EGGEPI-ESLDILEIFHSMGLRVLTLTWSLRNQIGD--GVFERTK----GGLTNFGAEVV 151
EGG I SL +L +F+ +G R LTLT + D V E K GGL+ FG VV
Sbjct: 184 EGGHAIGTSLSVLRMFYQLGARYLTLTHTCNTPWADCCKVDEPGKYPHIGGLSQFGKLVV 243
Query: 152 GKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERD 211
+ LG+IVD+SH++ D L + P+I SHS+A A+C+ RN+ D ++ IA
Sbjct: 244 KEMNRLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAHAICNSSRNVPDHVLQRIAING 303
Query: 212 GVIGAVAIPEFVD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLED 270
G++ P FV + TL V HI ++ ++ G HVGIG Y G +GLED
Sbjct: 304 GLVMVAFYPHFVSCSGQATLHDVVAHINHIREVAGIDHVGIGAG---YDGVNLVPKGLED 360
Query: 271 ESKIPALIDTL--NEKFSEKEVKAIAFENFKRVFERV 305
SK P L L ++K+SE+++ +A N RVF+ V
Sbjct: 361 VSKYPHLFAALLESDKWSEEDIAKLAGRNLIRVFKEV 397
>dbj|BAA02431.1| (D13138) dipeptidase precursor [Homo sapiens]
Length = 411
Score = 133 bits (331), Expect = 3e-30
Identities = 101/325 (31%), Positives = 164/325 (50%), Gaps = 24/325 (7%)
Query: 2 IFDAHSDLP---TFVYNER---EKGKTRVL---ESNFEKFFTG-ISARVMSVWSRPD-KR 50
+ D H+DLP ++N R E+ L +N K G + + SV++ D +
Sbjct: 32 VIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQN 91
Query: 51 PVILRYALEAYNRLFKDVSE-SERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LD 108
+R LE + + + E F V + + +A +EGKVA +G+EGG PI+S L
Sbjct: 92 KDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHPIDSSLG 151
Query: 109 ILEIFHSMGLRVLTLT------WSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVD 162
+L + +G+R LTLT WS + G E GL+ FG VV + LG+++D
Sbjct: 152 VLRALYQLGMRYLTLTHSCNTPWSDNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLID 211
Query: 163 VSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEF 222
++H++ L ++ PVI SHS+A ++C RN+ DD ++ + + D ++ +
Sbjct: 212 LAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNY 271
Query: 223 VD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DT 280
+ K L + H++++ ++ G + VG G DF G + EGLED SK P LI +
Sbjct: 272 ISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFD---GVPRVPEGLEDVSKYPDLIAEL 328
Query: 281 LNEKFSEKEVKAIAFENFKRVFERV 305
L ++E EVK +N RVFE V
Sbjct: 329 LRRNWTEAEVKGALADNLLRVFEAV 353
>sp|P16444|MDP1_HUMAN MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEHYDROPEPTIDASE-I) (RENAL
DIPEPTIDASE) (RDP) >gi|345825|pir||S29848 membrane
dipeptidase (EC 3.4.13.19) precursor - human
>gi|219600|dbj|BAA02430.1| (D13137) dipeptidase
precursor [Homo sapiens] >gi|8248922|gb|AAC60630.2|
(S70330) renal dipeptidase; RDP [Homo sapiens]
Length = 411
Score = 129 bits (320), Expect = 6e-29
Identities = 100/325 (30%), Positives = 162/325 (49%), Gaps = 24/325 (7%)
Query: 2 IFDAHSDLP---TFVYNER---EKGKTRVL---ESNFEKFFTG-ISARVMSVWSRPD-KR 50
+ D H+DLP ++N R E+ L +N K G + + SV++ D +
Sbjct: 32 VIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQN 91
Query: 51 PVILRYALEAYNRLFKDVSE-SERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LD 108
+R LE + + + E F V + + +A +EGKVA +G+EGG I+S L
Sbjct: 92 KDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLG 151
Query: 109 ILEIFHSMGLRVLTLTWSLRNQIGD------GVFERTKGGLTNFGAEVVGKCEELGIIVD 162
+L + +G+R LTLT S D G E GL+ FG VV + LG+++D
Sbjct: 152 VLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLID 211
Query: 163 VSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEF 222
++H++ L ++ PVI SHS+A ++C RN+ DD ++ + + D ++ +
Sbjct: 212 LAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNY 271
Query: 223 VD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DT 280
+ K L + H++++ ++ G + VG G DF G + EGLED SK P LI +
Sbjct: 272 ISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFD---GVPRVPEGLEDVSKYPDLIAEL 328
Query: 281 LNEKFSEKEVKAIAFENFKRVFERV 305
L ++E EVK +N RVFE V
Sbjct: 329 LRRNWTEAEVKGALADNLLRVFEAV 353
>gi|4758190 dipeptidase 1 (renal) [Homo sapiens] >gi|598189|gb|AAB59410.1|
(J05257) microsomal dipeptidase [Homo sapiens]
>gi|444784|prf||1908219A dipeptidase [Homo sapiens]
>gi|744584|prf||2015206A dipeptidase [Homo sapiens]
Length = 411
Score = 129 bits (320), Expect = 6e-29
Identities = 100/325 (30%), Positives = 162/325 (49%), Gaps = 24/325 (7%)
Query: 2 IFDAHSDLP---TFVYNER---EKGKTRVL---ESNFEKFFTG-ISARVMSVWSRPD-KR 50
+ D H+DLP ++N R E+ L +N K G + + SV++ D +
Sbjct: 32 VIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQN 91
Query: 51 PVILRYALEAYNRLFKDVSE-SERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LD 108
+R LE + + + E F V + + +A +EGKVA +G+EGG I+S L
Sbjct: 92 KDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLG 151
Query: 109 ILEIFHSMGLRVLTLTWSLRNQIGD------GVFERTKGGLTNFGAEVVGKCEELGIIVD 162
+L + +G+R LTLT S D G E GL+ FG VV + LG+++D
Sbjct: 152 VLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLID 211
Query: 163 VSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEF 222
++H++ L ++ PVI SHS+A ++C RN+ DD ++ + + D ++ +
Sbjct: 212 LAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNY 271
Query: 223 VD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DT 280
+ K L + H++++ ++ G + VG G DF G + EGLED SK P LI +
Sbjct: 272 ISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFD---GVPRVPEGLEDVSKYPDLIAEL 328
Query: 281 LNEKFSEKEVKAIAFENFKRVFERV 305
L ++E EVK +N RVFE V
Sbjct: 329 LRRNWTEAEVKGALADNLLRVFEAV 353
>gi|11641269 putative dipeptidase [Homo sapiens] >gi|11071729|emb|CAC14667.1|
(AJ295149) putative dipeptidase [Homo sapiens]
Length = 486
Score = 128 bits (319), Expect = 7e-29
Identities = 98/324 (30%), Positives = 167/324 (51%), Gaps = 28/324 (8%)
Query: 2 IFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTG--------ISARVMSVW--SRPDKRP 51
+ D H+DLP + +KG V NF T + A+ S + + R
Sbjct: 85 LVDGHNDLPLVLRQVYQKGLQDVNLRNFSYGQTSLDRLRDGLVGAQFWSAYVPCQTQDRD 144
Query: 52 VILRYALEAYNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIE-SLDIL 110
LR LE + + + + +V + K +++ K+A +G+EGG ++ SL IL
Sbjct: 145 A-LRLTLEQIDLIRRMCASYSELELVTSAKALNDT---QKLACLIGVEGGHSLDNSLSIL 200
Query: 111 EIFHSMGLRVLTLT------WSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVS 164
F+ +G+R LTLT W+ + G F GLT+FG +VV + LG++VD+S
Sbjct: 201 RTFYMLGVRYLTLTHTCNTPWAESSAKGVHSFYNNISGLTDFGEKVVAEMNRLGMMVDLS 260
Query: 165 HINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVD 224
H+++ L+++ PVI SHS A+ +C+ RN+ DD ++ + + GV+ V++ V
Sbjct: 261 HVSDAVARRALEVSQAPVIFSHSAARGVCNSARNVPDDILQLLKKNGGVV-MVSLSMGVI 319
Query: 225 KEKPT--LEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DTL 281
+ P+ + H +++ ++G K +GIG D Y G+ K +GLED S P LI + L
Sbjct: 320 QCNPSANVSTVADHFDHIKAVIGSKFIGIGGD---YDGAGKFPQGLEDVSTYPVLIEELL 376
Query: 282 NEKFSEKEVKAIAFENFKRVFERV 305
+ +SE+E++ + N RVF +V
Sbjct: 377 SRGWSEEELQGVLRGNLLRVFRQV 400
>sp|P31430|MDP1_RAT MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEHYDROPEPTIDASE-I) (RENAL
DIPEPTIDASE) (RDP) >gi|285150|pir||S27204 membrane
dipeptidase (EC 3.4.13.19) precursor - rat
>gi|203970|gb|AAA41093.1| (M94056) dipeptidase [Rattus
norvegicus]
Length = 410
Score = 126 bits (314), Expect = 3e-28
Identities = 96/331 (29%), Positives = 158/331 (47%), Gaps = 36/331 (10%)
Query: 2 IFDAHSDLP----TFVYNEREKGKTRV-----LESNFEKFFTG-ISARVMSVWSRPDKRP 51
+ D H+DLP T N+ K + + +N K G + + S + D +
Sbjct: 32 VIDGHNDLPWQMLTLFNNQLRKSEANLSALAETHTNIPKLRAGFVGGQFWSAYMPCDTQN 91
Query: 52 VILRYALEAYNRLFKDVSESER--------FRIVGTVKEMDEAIKEGKVALWLGMEGGEP 103
+A R+ + + R F V ++ +A + GKVA +G+EGG
Sbjct: 92 K------DAVKRILEQIDVIHRMCQLYPETFECVTNSSDILQAFRRGKVASLIGVEGGHL 145
Query: 104 IES-LDILEIFHSMGLRVLTLT------WSLRNQIGDGVFERTKGGLTNFGAEVVGKCEE 156
I+S L +L + +G+R LTLT W+ + G E GL+ FG V+ +
Sbjct: 146 IDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDKGDDEAESQGLSPFGKLVLNEMNR 205
Query: 157 LGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGA 216
LG+++D+SH++ D L ++ PVI SHS+A ++C H RN+ DD ++ + + ++
Sbjct: 206 LGVMIDLSHVSVATMKDALQLSKAPVIFSHSSAYSVCPHRRNVPDDVLQLVKSTNSLVMV 265
Query: 217 VAIPEFVD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIP 275
+FV + TL + H++++ + G VG+G D Y G GLED SK P
Sbjct: 266 NFYNQFVSCSDSATLSQVADHLDHIKKVAGAGAVGLGGD---YDGVTNLPVGLEDVSKYP 322
Query: 276 ALI-DTLNEKFSEKEVKAIAFENFKRVFERV 305
LI + L ++E EV+ + EN RVF V
Sbjct: 323 DLIAELLRRNWTETEVRGLLAENLLRVFSAV 353
>gb|AAA41094.1| (L07315) dipeptidase [Rattus norvegicus] >gi|459935|gb|AAA41095.1|
(L07316) dipeptidase [Rattus norvegicus]
Length = 410
Score = 126 bits (314), Expect = 3e-28
Identities = 96/331 (29%), Positives = 158/331 (47%), Gaps = 36/331 (10%)
Query: 2 IFDAHSDLP----TFVYNEREKGKTRV-----LESNFEKFFTG-ISARVMSVWSRPDKRP 51
+ D H+DLP T N+ K + + +N K G + + S + D +
Sbjct: 32 VIDGHNDLPWQMLTLFNNQLRKSEANLSALAETHTNIPKLRAGFVGGQFWSAYMPCDTQN 91
Query: 52 VILRYALEAYNRLFKDVSESER--------FRIVGTVKEMDEAIKEGKVALWLGMEGGEP 103
+A R+ + + R F V ++ +A + GKVA +G+EGG
Sbjct: 92 K------DAVKRILEQIDVIHRMCQLYPETFECVTNSSDILQAFRRGKVASLIGVEGGHL 145
Query: 104 IES-LDILEIFHSMGLRVLTLT------WSLRNQIGDGVFERTKGGLTNFGAEVVGKCEE 156
I+S L +L + +G+R LTLT W+ + G E GL+ FG V+ +
Sbjct: 146 IDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDKGDDEAESQGLSPFGKLVLNEMNR 205
Query: 157 LGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGA 216
LG+++D+SH++ D L ++ PVI SHS+A ++C H RN+ DD ++ + + ++
Sbjct: 206 LGVMIDLSHVSVATMKDALQLSKAPVIFSHSSAYSVCPHRRNVPDDVLQLVKSTNSLVMV 265
Query: 217 VAIPEFVD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIP 275
+FV + TL + H++++ + G VG+G D Y G GLED SK P
Sbjct: 266 NFYNQFVSCSDSATLSQVADHLDHIKKVAGAGAVGLGGD---YDGVTNLPVGLEDVSKYP 322
Query: 276 ALI-DTLNEKFSEKEVKAIAFENFKRVFERV 305
LI + L ++E EV+ + EN RVF V
Sbjct: 323 DLIAELLRRNWTETEVRGLLAENLLRVFSAV 353
>gb|AAF49997.1| (AE003543) CG5917 gene product [Drosophila melanogaster]
Length = 521
Score = 125 bits (312), Expect = 5e-28
Identities = 81/229 (35%), Positives = 126/229 (54%), Gaps = 7/229 (3%)
Query: 81 KEMDEAIKEGKVALWLGMEGGEPI-ESLDILEIFHSMGLRVLTLTWSLRNQIGDGVFERT 139
+++ +A + G +A +G+EGG I SL +L F+S+G R L+LT
Sbjct: 265 QDIVDAHRRGLLASLIGVEGGHTIGSSLGVLRSFYSLGARYLSLTHRCDVSWAGSSASPA 324
Query: 140 KGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNL 199
+ GLT FG +V + LG+++D+SH ++ DVL +T PVI SHS A+ LC+ RN+
Sbjct: 325 EQGLTPFGKAIVREMNRLGMMIDLSHSSDATARDVLQVTRAPVIFSHSAARQLCNSTRNV 384
Query: 200 TDDQIKAIAERDGVIGAVAIPEFVD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYY 258
DD ++ +AE G+I E V + L+ + HI+Y+ + G +H+G+G Y
Sbjct: 385 PDDILRLVAENGGLIMLSFDSEDVACGRQARLQDVIEHIKYVRAIAGIQHIGLGAG---Y 441
Query: 259 LGSKKSVEGLEDESKIPALIDTLNE--KFSEKEVKAIAFENFKRVFERV 305
G + GLED SK P L+ L E +SE++V +A NF R+ E V
Sbjct: 442 DGIELPPLGLEDVSKYPELLAALLEDHNWSEEDVAMLAGRNFLRIMETV 490
>pir||T41665 probable dipeptidase - fission yeast (Schizosaccharomyces pombe)
>gi|3136041|emb|CAA19072.1| (AL023590) putative
dipeptidase [Schizosaccharomyces pombe]
Length = 416
Score = 125 bits (311), Expect = 6e-28
Identities = 77/235 (32%), Positives = 134/235 (56%), Gaps = 17/235 (7%)
Query: 84 DEAI----KEGKVALWLGMEGGEPIE-SLDILEIFHSMGLRVLTLTWSLRNQIGDGVFER 138
D+AI GK+A+ LG+EG ++ SL +L ++S+G+R +TLT + N
Sbjct: 125 DDAIAAFRNNGKIAIALGVEGLHQVDTSLAVLRQYYSLGVRYITLTHNCDNPFATAASSI 184
Query: 139 TKG----GLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCD 194
T G GL+ +G E + + LG++VD+SH++ + D LD+T PVI SHS+A L +
Sbjct: 185 TGGLPDRGLSAYGIECIFEMNRLGMMVDLSHVSHRTMHDALDVTKAPVIFSHSSAYTLTE 244
Query: 195 HVRNLTDDQIKAIAERDGVIGAVAIPEFVDK---EKPTLEKYVRHIEYMVDLVGYKHVGI 251
H RN+ DD ++ + GV+ +F+ K ++ T++ HI +++ + G++HVG+
Sbjct: 245 HERNVRDDVLERLKTNGGVVQVNFYQDFIRKPGSDRATIDDAADHILHIIKVAGWEHVGL 304
Query: 252 GLDFVYYLGSKKSVEGLEDESKIPALIDTLNEK--FSEKEVKAIAFENFKRVFER 304
G DF G + +GLED SK P LI + E+ + ++++ + N RV+++
Sbjct: 305 GSDFD---GIPQGPKGLEDVSKYPDLICKIIERTNATNEQIEGLMGLNVLRVWKK 356
>pir||S33757 membrane dipeptidase (EC 3.4.13.19) precursor - mouse
Length = 410
Score = 125 bits (310), Expect = 8e-28
Identities = 81/243 (33%), Positives = 127/243 (51%), Gaps = 12/243 (4%)
Query: 72 ERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LDILEIFHSMGLRVLTLT------ 124
E F V ++ +A + GKVA +G+EGG I+S L +L + +G+R LTLT
Sbjct: 114 ETFMCVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTP 173
Query: 125 WSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIA 184
W+ + G E GL+ FG ++ + LG+++D+SH++ D L I+ PVI
Sbjct: 174 WADNWLVDRGDDEAESHGLSPFGKRLLNEMNRLGVMIDLSHVSVATMKDALQISRAPVIF 233
Query: 185 SHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVD-KEKPTLEKYVRHIEYMVDL 243
SHS+A +LC H RN+ DD ++ + ++ FV + TL + H++++ +
Sbjct: 234 SHSSAYSLCPHRRNVPDDVLQLVKNTSSLVMVNFFSNFVSCSDSATLPQVADHLDHIKKV 293
Query: 244 VGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DTLNEKFSEKEVKAIAFENFKRVF 302
G VG+G D Y G GLED SK P LI + L ++E EV+ + +N RVF
Sbjct: 294 AGAGAVGLGGD---YDGVTMLPVGLEDVSKYPDLIAELLRRNWTETEVRGLLADNLIRVF 350
Query: 303 ERV 305
V
Sbjct: 351 SEV 353
>sp|P43477|MDP1_SHEEP MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEHYDROPEPTIDASE-I) (RENAL
DIPEPTIDASE) (RDP) >gi|436191|gb|AAA21725.1| (L27113)
microsomal dipeptidase [Ovis ammon]
>gi|1090532|prf||2019262A dipeptidase [Ovis aries]
Length = 410
Score = 125 bits (310), Expect = 8e-28
Identities = 82/243 (33%), Positives = 129/243 (52%), Gaps = 12/243 (4%)
Query: 72 ERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LDILEIFHSMGLRVLTLTWSLRNQ 130
E F V + +A +EGKVA +G+EGG I+S L +L + +G+R LTLT S
Sbjct: 114 ETFLCVTDSAGIQQAFQEGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYLTLTHSCNTP 173
Query: 131 IGD------GVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIA 184
D G + GL++FG VV + LGII+D++H++ L ++ PVI
Sbjct: 174 WADNWLVDTGEDKAQSQGLSSFGQSVVKEMNRLGIIIDLAHVSVATMEAALQLSKAPVIF 233
Query: 185 SHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVD-KEKPTLEKYVRHIEYMVDL 243
SHS+A +LC H RN+ D ++ + + ++ ++V K + L + H++Y+ +
Sbjct: 234 SHSSAYSLCHHRRNVPDHVLQLVKQTGSLVMVNFYNDYVSCKAEANLSQVADHLDYIKKV 293
Query: 244 VGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DTLNEKFSEKEVKAIAFENFKRVF 302
G VG G D Y G + GLED SK P L+ + L +++E+EV+ EN RVF
Sbjct: 294 AGAGAVGFGGD---YDGVSRLPSGLEDVSKYPDLVAELLRRQWTEEEVRGALAENLLRVF 350
Query: 303 ERV 305
+ V
Sbjct: 351 KAV 353
>gi|6681217 dipeptidase 1 (renal) [Mus musculus]
>gi|400238|sp|P31428|MDP1_MOUSE MICROSOMAL DIPEPTIDASE
PRECURSOR (MDP) (DEHYDROPEPTIDASE-I) (RENAL DIPEPTIDASE)
(RDP) >gi|220398|dbj|BAA02432.1| (D13139) dipeptidase
precursor [Mus musculus]
Length = 410
Score = 124 bits (309), Expect = 1e-27
Identities = 81/243 (33%), Positives = 127/243 (51%), Gaps = 12/243 (4%)
Query: 72 ERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LDILEIFHSMGLRVLTLT------ 124
E F V ++ +A + GKVA +G+EGG I+S L +L + +G+R LTLT
Sbjct: 114 ETFMCVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTP 173
Query: 125 WSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIA 184
W+ + G E GL+ FG ++ + LG+++D+SH++ D L I+ PVI
Sbjct: 174 WADNWLVDRGDDEAESHGLSPFGKRLLNEMTRLGVMIDLSHVSVATMKDALQISRAPVIF 233
Query: 185 SHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVD-KEKPTLEKYVRHIEYMVDL 243
SHS+A +LC H RN+ DD ++ + ++ FV + TL + H++++ +
Sbjct: 234 SHSSAYSLCPHRRNVPDDVLQLVKNTSSLVMVNFFSNFVSCSDSATLPQVADHLDHIKKV 293
Query: 244 VGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DTLNEKFSEKEVKAIAFENFKRVF 302
G VG+G D Y G GLED SK P LI + L ++E EV+ + +N RVF
Sbjct: 294 AGAGAVGLGGD---YDGVTMLPVGLEDVSKYPDLIAELLRRNWTETEVRGLLADNLIRVF 350
Query: 303 ERV 305
V
Sbjct: 351 SEV 353
>sp|P31429|MDP1_RABIT MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEHYDROPEPTIDASE-I) (RENAL
DIPEPTIDASE) (RDP) (43 KDA RENAL BAND 3-RELATED PROTEIN)
>gi|109139|pir||S18442 membrane dipeptidase (EC
3.4.13.19) precursor - rabbit >gi|1424|emb|CAA43720.1|
(X61503) 43-KDa rabbit renal band 3-related protein
[Oryctolagus cuniculus]
Length = 410
Score = 124 bits (308), Expect = 1e-27
Identities = 97/325 (29%), Positives = 158/325 (47%), Gaps = 24/325 (7%)
Query: 2 IFDAHSDLPTFVYN------EREKGKTRVL---ESNFEKFFTG-ISARVMSVWSRPD-KR 50
+ D H+DLP + N + + VL +N K G + + S ++ D +
Sbjct: 32 VIDGHNDLPWQLLNKFNNRLQDSRANLTVLADTHTNIPKLRAGFVGGQFWSAYTPCDTQN 91
Query: 51 PVILRYALEAYNRLFKDVS-ESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LD 108
+R LE + + + E F V + +A +EGKVA +G+EGG I+S L
Sbjct: 92 KDTVRRTLEQMDVVHRMCQLYPETFLCVTDSAGIQQAFREGKVASLIGVEGGHSIDSSLG 151
Query: 109 ILEIFHSMGLRVLTLT------WSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVD 162
+L + +G+R LTLT W+ + G E GGL+ FG VV + LG+++D
Sbjct: 152 VLRALYRLGMRYLTLTHNCNTPWADNWLVDRGDDEAQSGGLSVFGQRVVREMNRLGVMID 211
Query: 163 VSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEF 222
++H++ L ++ PVI SHS+A +C H RN+ DD ++ + E ++ ++
Sbjct: 212 LAHVSVATMKAALQLSTAPVIFSHSSAFTVCAHKRNVPDDVLQLVKETGSLVMVNFYNDY 271
Query: 223 VD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DT 280
V + TL + H++Y+ ++ G V G DF G + GLED SK P L+ +
Sbjct: 272 VSCASEATLSQVADHLDYIKNVAGAAAVRFGGDFD---GVTRLPVGLEDVSKYPDLVAEL 328
Query: 281 LNEKFSEKEVKAIAFENFKRVFERV 305
L ++E EV+ EN RVF V
Sbjct: 329 LRRGWTEAEVRGALAENLLRVFREV 353
>sp|P22412|MDP1_PIG MICROSOMAL DIPEPTIDASE PRECURSOR (MDP) (DEHYDROPEPTIDASE-I) (RENAL
DIPEPTIDASE) (RDP) >gi|280890|pir||JS0759 membrane
dipeptidase (EC 3.4.13.19) precursor - pig
>gi|2102|emb|CAA37762.1| (X53730) dipeptidase [Sus
scrofa] >gi|217705|dbj|BAA02433.1| (D13142) dipeptidase
precursor [Sus scrofa]
Length = 409
Score = 124 bits (308), Expect = 1e-27
Identities = 80/243 (32%), Positives = 129/243 (52%), Gaps = 12/243 (4%)
Query: 72 ERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LDILEIFHSMGLRVLTLTWSLRNQ 130
E F V + + +A +EGKVA +G+EGG I+S L +L + +G+R +TLT S
Sbjct: 114 ETFACVTSSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTP 173
Query: 131 IGD------GVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIA 184
D G + GL++FG VV + LG+++D++H++ L ++ PVI
Sbjct: 174 WADNWLVDTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIF 233
Query: 185 SHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVD-KEKPTLEKYVRHIEYMVDL 243
SHS+A +LC H RN+ DD ++ + E ++ ++V K L + H++++ +
Sbjct: 234 SHSSAYSLCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKV 293
Query: 244 VGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DTLNEKFSEKEVKAIAFENFKRVF 302
G VG G D Y G + GLED SK P L+ + L +++E EV+ +N RVF
Sbjct: 294 AGAAAVGFGGD---YDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVF 350
Query: 303 ERV 305
E V
Sbjct: 351 EAV 353
>pir||T01637 gene R protein - Acinetobacter calcoaceticus (fragment)
>gi|38746|emb|CAA29758.1| (X06452) R protein
[Acinetobacter calcoaceticus]
Length = 316
Score = 120 bits (299), Expect = 2e-26
Identities = 62/186 (33%), Positives = 111/186 (59%), Gaps = 12/186 (6%)
Query: 71 SERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIE-SLDILEIFHSMGLRVLTLTWSLRN 129
S+ +I +V+++ + E K+A+ L MEG E ++ + D+L++F+ GLR + W+ +
Sbjct: 104 SKNIKICTSVQDIQDCRAEKKLAIVLHMEGAEALQQNPDLLDVFYERGLRSIGPLWNRPS 163
Query: 130 QIGDGVFER------TKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVI 183
+ G G+ + T GLT+ G + + +C +++DVSH+NE+ FW+ +DI P++
Sbjct: 164 RFGHGLNAKFPHSPDTGAGLTSDGKDFIKRCANKKMVIDVSHMNEKAFWNTVDILQQPIV 223
Query: 184 ASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKE-----KPTLEKYVRHIE 238
A+HSN+ ALC RNLTD Q+KAI E G++G F+ + +++ + H+E
Sbjct: 224 ATHSNSHALCPQARNLTDPQLKAIRESKGMVGVNFDVAFLRSDGQRNADTSIDVILEHLE 283
Query: 239 YMVDLV 244
Y++D V
Sbjct: 284 YLMDRV 289
>sp|P07783|YPQR_ACICA HYPOTHETICAL PROTEIN IN PQQ-III 3'REGION (ORF R)
>gi|95322|pir||G32252 gene R protein - Acinetobacter
calcoaceticus (fragment)
Length = 315
Score = 120 bits (299), Expect = 2e-26
Identities = 62/186 (33%), Positives = 111/186 (59%), Gaps = 12/186 (6%)
Query: 71 SERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIE-SLDILEIFHSMGLRVLTLTWSLRN 129
S+ +I +V+++ + E K+A+ L MEG E ++ + D+L++F+ GLR + W+ +
Sbjct: 104 SKNIKICTSVQDIQDCRAEKKLAIVLHMEGAEALQQNPDLLDVFYERGLRSIGPLWNRPS 163
Query: 130 QIGDGVFER------TKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVI 183
+ G G+ + T GLT+ G + + +C +++DVSH+NE+ FW+ +DI P++
Sbjct: 164 RFGHGLNAKFPHSPDTGAGLTSDGKDFIKRCANKKMVIDVSHMNEKAFWNTVDILQQPIV 223
Query: 184 ASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKE-----KPTLEKYVRHIE 238
A+HSN+ ALC RNLTD Q+KAI E G++G F+ + +++ + H+E
Sbjct: 224 ATHSNSHALCPQARNLTDPQLKAIRESKGMVGVNFDVAFLRSDGQRNADTSIDVILEHLE 283
Query: 239 YMVDLV 244
Y++D V
Sbjct: 284 YLMDRV 289
>pir||H72724 probable microsomal dipeptidase APE0337 - Aeropyrum pernix (strain
K1) >gi|5103976|dbj|BAA79292.1| (AP000059) 313aa long
hypothetical microsomal dipeptidase [Aeropyrum pernix]
Length = 313
Score = 119 bits (295), Expect = 5e-26
Identities = 67/218 (30%), Positives = 120/218 (54%), Gaps = 3/218 (1%)
Query: 91 KVALWLGMEGGEPIESLDILEIFHSMGLRVLTLTWSLRNQIGDGVFERTKGGLTNFGAEV 150
++ L L +EG + + + LE+ H +G R L LTW+ N+ R GLT G ++
Sbjct: 94 RLGLLLHLEGADALADILDLELLHRLGFRSLGLTWNHDNRWAASCKTRRDYGLTQSGEDL 153
Query: 151 VGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAER 210
V K ELG+I+D++H +++ D + PVI SH+N + D RN+ ++ ++A+ +
Sbjct: 154 VKKAAELGVIIDLAHASDKTVADAASASPKPVIVSHANFRWKVDSPRNVGEEAVEAVVSK 213
Query: 211 DGVIGAVAIPEFVDKEK-PTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLE 269
GVIG I + + + PTL + V++ G++H+ IG D+ + L + GLE
Sbjct: 214 GGVIGYSLISTLITRGRHPTLHDVASQMAEFVEVYGHRHLAIGTDY-HGLLDIRPPTGLE 272
Query: 270 DESKIPALIDTLNEK-FSEKEVKAIAFENFKRVFERVV 306
++P L++ L + S+++++AIA+ N RV V+
Sbjct: 273 SIDRLPRLLEALADAGLSDRQIEAIAYGNIARVIREVL 310
>sp|P27509|YPQQ_KLEPN HYPOTHETICAL PROTEIN IN PQQA 5'REGION (ORF X) >gi|78961|pir||S20452
hypothetical protein X - Klebsiella pneumoniae
(fragment) >gi|43904|emb|CAA41578.1| (X58778) orfX
[Klebsiella pneumoniae]
Length = 271
Score = 117 bits (290), Expect = 2e-25
Identities = 78/248 (31%), Positives = 131/248 (52%), Gaps = 21/248 (8%)
Query: 73 RFRIVGTVKEMDEAIKEGKVALWLGMEG--GEPIESLDILEIFHSMGLRVLTLTWSLRNQ 130
R R+ + +++ ++ +A+ +EG G E D L+ F++ G+R + W++ N+
Sbjct: 27 RLRLCLSAADIERCREDKVLAMVAHIEGAGGFDGEGRD-LQAFYAAGVRSIGPFWNIANR 85
Query: 131 IGDGVFERTKG------GLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIA 184
G GV G GLT G +++ + L + +DVSH+NE+ FWD P++A
Sbjct: 86 FGSGVNGSFPGSPDTGPGLTAAGIDLIKQVNALKMQIDVSHMNEKAFWDTAHHATSPLVA 145
Query: 185 SHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFV------DKEKPTLEKYVRHIE 238
+HSNA ALC RNLTD Q++AI + GV+G F+ D + P L VRHI+
Sbjct: 146 THSNAHALCPQPRNLTDQQLRAIRDSGGVVGVNFGNAFLRADGRRDSDTP-LTTIVRHID 204
Query: 239 YMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDTLNEK-FSEKEVKAIAFEN 297
Y+++++G HV +G DF + L D + +P LI+TL + + + + + N
Sbjct: 205 YLINIMGEDHVALGSDF----DGITLPDELGDVAGLPRLINTLRASGYDQLVLDKLLWRN 260
Query: 298 FKRVFERV 305
+ RV + V
Sbjct: 261 WLRVLKNV 268
>pir||T11632 membrane dipeptidase (EC 3.4.13.19) - fission yeast
(Schizosaccharomyces pombe) >gi|2414638|emb|CAB16385.1|
(Z99260) putative microsomal dipeptidase precursor
[Schizosaccharomyces pombe]
Length = 409
Score = 115 bits (286), Expect = 5e-25
Identities = 77/219 (35%), Positives = 116/219 (52%), Gaps = 10/219 (4%)
Query: 92 VALWLGMEGGEPIE-SLDILEIFHSMGLRVLTLTWSLRNQIGDGVFE--RTKGGLTNFGA 148
++ +G+EG I S IL F+ +G+R TL + N D + RT GL+ G
Sbjct: 174 ISSMMGIEGLHQIAGSPSILRQFYDLGVRYATLAHNCDNVFADAAVDGKRTNKGLSPAGR 233
Query: 149 EVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIA 208
++V + LG+IVD+SH + LD++ P SHS+AK + DH RN+ DD + +
Sbjct: 234 DIVREMNRLGMIVDLSHTTPETMHQALDVSVAPAFFSHSSAKGVYDHPRNVPDDVLIRVK 293
Query: 209 ERDGVIGAVAIPEFVD--KEKPTLEKYVRHIEYMVDLVG-YKHVGIGLDFVYYLGSKKSV 265
E DGV+ P F+ E T++ V HI ++ ++ G Y+H+G+G DF G
Sbjct: 294 ETDGVVMVNFYPAFISPHPENATIDTVVEHIMHIANVTGSYRHIGLGGDFD---GIDMVP 350
Query: 266 EGLEDESKIPALIDTLNEK-FSEKEVKAIAFENFKRVFE 303
+GLED SK P L L E+ S E+ IA N RV++
Sbjct: 351 KGLEDVSKYPDLFVKLAERGLSITELADIAGRNVLRVWK 389
>pir||D82971 hypothetical protein PA5396 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9951721|gb|AAG08781.1|AE004952_3
(AE004952) hypothetical protein [Pseudomonas aeruginosa]
Length = 325
Score = 113 bits (279), Expect = 4e-24
Identities = 75/274 (27%), Positives = 136/274 (49%), Gaps = 27/274 (9%)
Query: 58 LEAYNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LDILEIFHSM 116
+ A N+L +D S+ V + ++ +A ++GK + G + E + +E+F +
Sbjct: 54 IAASNKLIRD--NSDLVIPVRSTADIRKAKEQGKTGILYGFQNAHAFEDQIGYVEVFKQL 111
Query: 117 GLRVLTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLD 176
G+ ++ + ++ +N +G G +ER GGL+ FG E+V + +GI+ D+SH+ + +V+
Sbjct: 112 GVGIVQMCYNTQNLVGTGCYERD-GGLSGFGREIVAEMNRVGIMCDLSHVGSKTSEEVIL 170
Query: 177 ITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKE-KPTLEKYVR 235
+ PV SH L +H RN +D+++K IA+ G +G F+ K T++ Y
Sbjct: 171 ESKKPVCYSHCLPSGLKEHPRNKSDEELKFIADHGGFVGVTMFAPFLKKGIDSTIDDYAE 230
Query: 236 HIEYMVDLVGYKHVGIGLDF---------------------VYYLGSKKSVEGLEDESKI 274
IEY++++VG +GIG DF + G + G+ +
Sbjct: 231 AIEYVMNIVGEDAIGIGTDFTQGHGHDFFEWLTHDKGYARRLTNFGKIVNPLGIRTVGEF 290
Query: 275 PALIDTLNEK-FSEKEVKAIAFENFKRVFERVVG 307
P L +TL E+ E+ V+ + EN+ RV V G
Sbjct: 291 PNLTETLLERGMPERVVRKVMGENWVRVLRDVWG 324
>pir||B71089 hypothetical protein PH0975 - Pyrococcus horikoshii
>gi|3257389|dbj|BAA30072.1| (AP000004) 110aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 110
Score = 112 bits (278), Expect = 5e-24
Identities = 55/101 (54%), Positives = 73/101 (71%), Gaps = 6/101 (5%)
Query: 98 MEGGEPI-ESLDILEIFHSMGLRVLTLTWSLRNQIGDGVFER-----TKGGLTNFGAEVV 151
MEG EP+ +++L IF+ +GLRVLT T S RN +GDG F + T GGLT FG EVV
Sbjct: 1 MEGAEPLGNDIEMLRIFYKLGLRVLTFTHSRRNYVGDGAFLKPQKSGTPGGLTPFGVEVV 60
Query: 152 GKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKAL 192
+ E+LGII+DVSH+N+ GFWDV++ + P+IA HSN +AL
Sbjct: 61 EQAEKLGIIIDVSHLNDPGFWDVIEFSKGPIIAPHSNCRAL 101
>gi|11641273 putative metallopeptidase (family M19) [Homo sapiens]
>gi|11125344|emb|CAC15385.1| (AJ291679) putative
metallopeptidase [Homo sapiens]
Length = 513
Score = 111 bits (276), Expect = 8e-24
Identities = 85/325 (26%), Positives = 166/325 (50%), Gaps = 30/325 (9%)
Query: 2 IFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTG-----------ISARVMSVW-SRPDK 49
+ D H+DLP + R++ K + + N F G + A+ S S +
Sbjct: 118 LVDGHNDLPQVL---RQRYKNVLQDVNLRNFSHGQTSLDRLRDGLVGAQFWSASVSCQSQ 174
Query: 50 RPVILRYALEAYNRLFKDVSESERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIES-LD 108
+R ALE + + + + +V + + ++ + K+A +G+EGG ++S L
Sbjct: 175 DQTAVRLALEQIDLIHRMCASYSELELVTSAEGLNSS---QKLACLIGVEGGHSLDSSLS 231
Query: 109 ILEIFHSMGLRVLTLTWSLRNQIGDGVFE------RTKGGLTNFGAEVVGKCEELGIIVD 162
+L F+ +G+R LTLT++ + + GLT+FG +VV + LG+++D
Sbjct: 232 VLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMID 291
Query: 163 VSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVI-GAVAIPE 221
+S+ ++ VL+++ PVI SHS A+A+CD++ N+ DD ++ + + G++ +++
Sbjct: 292 LSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKKNGGIVMVTLSMGV 351
Query: 222 FVDKEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALI-DT 280
+ H +++ ++G + +GIG + Y G+ + +GLED S P LI +
Sbjct: 352 LQCNLLANVSTVADHFDHIRAVIGSEFIGIGGN---YDGTGRFPQGLEDVSTYPVLIEEL 408
Query: 281 LNEKFSEKEVKAIAFENFKRVFERV 305
L+ +SE+E++ + N RVF +V
Sbjct: 409 LSRSWSEEELQGVLRGNLLRVFRQV 433
>gb|AAK42051.1| Microsomal dipeptidase [Sulfolobus solfataricus]
Length = 314
Score = 105 bits (259), Expect = 8e-22
Identities = 67/206 (32%), Positives = 110/206 (52%), Gaps = 6/206 (2%)
Query: 72 ERFRIVGTVKEMDEAIKEGKVALWLGMEGGEPIESLDILEIFHSMGLRVLTLTWSLRNQI 131
ER +V V+ ++ KEG V L L +EG + + + + + + L LTW+ N+
Sbjct: 90 ERKNLVKIVRSANDLEKEG-VKLLLSLEGADVLRDYSDIYLLKELHVLNLGLTWNYDNKF 148
Query: 132 GDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKA 191
+ GLT+ G E+V +LGII+D++H ++ DV + PVI SH+N
Sbjct: 149 ASSCMSKKDYGLTSEGEELVRLANKLGIIIDLAHAGKRTVLDVTSTSKKPVIDSHTNFTR 208
Query: 192 LCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEKPTLEKYVRHIEYMVDLVGYKHVGI 251
L H RNL D++I+AI + GVIG AI + ++ ++ V I+Y+ + G+ +V I
Sbjct: 209 LKQHRRNLDDEEIEAIVKTKGVIGITAIVATL--KEASISGIVESIKYLGESFGWDYVAI 266
Query: 252 GLDFVYYLGSKKSVEGLEDESKIPAL 277
G DF LG ++ +G E+ K+ L
Sbjct: 267 GTDF---LGIGEAPKGFENILKVKEL 289
>gi|11431942 dipeptidase 1 (renal) [Homo sapiens]
Length = 573
Score = 86.6 bits (211), Expect = 3e-16
Identities = 51/158 (32%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Query: 150 VVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAE 209
VV + LG+++D++H++ L ++ PVI SHS+A ++C RN+ DD ++ + +
Sbjct: 361 VVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQ 420
Query: 210 RDGVIGAVAIPEFVD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGL 268
D ++ ++ K L + H++++ ++ G + VG G DF G + EGL
Sbjct: 421 TDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFD---GVPRVPEGL 477
Query: 269 EDESKIPALI-DTLNEKFSEKEVKAIAFENFKRVFERV 305
ED SK P LI + L ++E EVK +N RVFE V
Sbjct: 478 EDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAV 515
>gb|AAF53657.1| (AE003658) CG7198 gene product [Drosophila melanogaster]
Length = 183
Score = 84.3 bits (205), Expect = 2e-15
Identities = 51/151 (33%), Positives = 86/151 (56%), Gaps = 5/151 (3%)
Query: 157 LGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGA 216
LG++VD+SH+++ D L+++ PVI SHS+A LC+ RN+ DD ++A+A+ G++
Sbjct: 4 LGMMVDLSHVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMV 63
Query: 217 VAIPEFVD-KEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIP 275
+F+ + T+ V HI ++ + G HVG+G Y G + +GLED S P
Sbjct: 64 NFYSKFLSCSDNSTVHDAVAHINHIKRVAGIDHVGLGAG---YDGINYTPKGLEDVSSYP 120
Query: 276 ALI-DTLNEKFSEKEVKAIAFENFKRVFERV 305
L + L ++ E+ +A NF RV ++V
Sbjct: 121 TLFAELLGGGWTIDELTKLAGGNFLRVMQQV 151
>pir||C71552 probable dipeptidase - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328538|gb|AAC67729.1| (AE001287)
Dipeptidase [Chlamydia trachomatis]
Length = 315
Score = 80.4 bits (195), Expect = 3e-14
Identities = 73/259 (28%), Positives = 117/259 (44%), Gaps = 16/259 (6%)
Query: 58 LEAYNRLFKD-VSESERFRIVGTVKEMD---EAIKEGKVALWLGMEGGEPIESLDILEIF 113
L+ N+LF + + ER + +++ + ++ + A LG + E L +
Sbjct: 51 LDEQNQLFFSLIEQDERLTPLSYEPQVESSLQVVRSIENASGLGSDAQPLQELFHKLLLL 110
Query: 114 HSMG-LRVLTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFW 172
H G L + L W+ N+ G G+ E + L+ G ++ L I VD+SH ++
Sbjct: 111 HEQGPLAYIGLVWNFANRFGGGILEPKR--LSRDGKNLLELLHALAIPVDLSHCSDPLAD 168
Query: 173 DVLDITAFP-----VIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEK 227
D+LD TA V+ASHSN +A+ D RNL D K I RDGVIG + FV
Sbjct: 169 DILDFTADKMPDMFVLASHSNFRAVQDIERNLLDVHAKEIFARDGVIGLNGVNYFVG--- 225
Query: 228 PTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLEDESKIPALIDTLNEKFSE 287
+LE +HI + +L + +G DF +Y +K P L + E
Sbjct: 226 ASLEDIKKHIAHAQELGILDSLVLGTDF-FYTEEEKFFPNFSTAKDHPKLHALIKEAIPI 284
Query: 288 KEVKAIAFENFKRVFERVV 306
+ +++ E +R RVV
Sbjct: 285 DKAQSLLEERAQRFLNRVV 303
>pir||H81704 dipeptidase, probable TC0415 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190457|gb|AAF39271.1| (AE002308)
dipeptidase, putative [Chlamydia muridarum]
Length = 315
Score = 78.4 bits (190), Expect = 1e-13
Identities = 85/296 (28%), Positives = 138/296 (45%), Gaps = 27/296 (9%)
Query: 1 MIFDAHSDLPTFVYNEREKGKTRVLESNFEKFFTGISARVMSVWSRPDKRPVILRYALEA 60
MI D H D+ + + V S + G++ +V ++++ + L+
Sbjct: 1 MIVDMHCDMLS--HENFSPANPAVRSSPDQLIEGGVNVQVCALFTESQEFTT-----LDQ 53
Query: 61 YNRLFKD-VSESERFRIVGTVKEMD---EAIKEGKVALWLGMEGGEPIESL-DILEIFHS 115
N+LF + + ER + +M+ + I+ + A LG + P+++L L I HS
Sbjct: 54 QNQLFFSLIEQDERLTPIAYEPQMEGSLQMIRSVENASGLGSDK-IPLQALFQKLLILHS 112
Query: 116 MG-LRVLTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDV 174
G L + L W+ N+ G GV E + L+ G ++ L I VD+SH ++Q D+
Sbjct: 113 QGPLAYVGLVWNFANRFGGGVLEPKR--LSKDGKNLLEFLYALAIPVDLSHCSDQLTEDI 170
Query: 175 LDITAFP-----VIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEKPT 229
LD T ++ASHSN + + RNL D K I R+GVIG + FV + +
Sbjct: 171 LDFTVDKLPNMFILASHSNFRKVQGVARNLLDVHAKEIFARNGVIGLNGVNYFVGE---S 227
Query: 230 LEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSK--KSVEGLEDESKIPALI-DTLN 282
LE +HI Y +L + +G DF Y K + +D K+ ALI DTL+
Sbjct: 228 LEDMRKHIAYAQELGILDGLVLGTDFFYTDEEKFFPNFSTAKDHPKLQALIEDTLS 283
>pir||B72098 dipeptidase, probable CP0490 [imported] - Chlamydophila pneumoniae
(strains CWL029 and AR39) >gi|4376542|gb|AAD18418.1|
(AE001612) Dipeptidase [Chlamydophila pneumoniae CWL029]
>gi|7189408|gb|AAF38320.1| (AE002210) dipeptidase,
putative [Chlamydophila pneumoniae AR39]
>gi|8978643|dbj|BAA98479.1| (AP002546) dipeptidase
[Chlamydophila pneumoniae J138]
Length = 325
Score = 77.3 bits (187), Expect = 2e-13
Identities = 52/145 (35%), Positives = 74/145 (50%), Gaps = 10/145 (6%)
Query: 118 LRVLTLTWSLRNQIGDGVFERTKGGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDI 177
L L + W N+ G G + L+N G ++ ELG+ +D+SH +++ D+LD
Sbjct: 123 LAYLGIVWKGDNRFGGGTEAPKR--LSNDGKVLLDIMYELGVPIDLSHCSDKLAEDILDY 180
Query: 178 TA-----FPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIGAVAIPEFVDKEKPTLEK 232
TA VIASHSN +++ DH RNL D K I R GVIG + +V LEK
Sbjct: 181 TADKLPNLAVIASHSNFRSVLDHRRNLVDAHAKEIVRRKGVIGLNLVRSYVGDSLGDLEK 240
Query: 233 YVRHIEYMVDLVGYKHVGIGLDFVY 257
+V H E + L + +G DF Y
Sbjct: 241 HVLHAENLGIL---SSIVLGSDFFY 262
>pir||C75406 probable peptidase - Deinococcus radiodurans (strain R1)
>gi|6459099|gb|AAF10917.1|AE001981_2 (AE001981)
peptidase, putative [Deinococcus radiodurans]
Length = 160
Score = 76.9 bits (186), Expect = 3e-13
Identities = 40/135 (29%), Positives = 74/135 (54%), Gaps = 7/135 (5%)
Query: 156 ELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNLTDDQIKAIAERDGVIG 215
+LG+ +D SH+++ FWD ++ ++++H+NA+AL R L+D+ + I GV+G
Sbjct: 6 DLGLTLDASHLDDVSFWDAAEL-GVRMVSTHANARALVPGNRQLSDEMARHIVSTGGVLG 64
Query: 216 AVAIPEFV------DKEKPTLEKYVRHIEYMVDLVGYKHVGIGLDFVYYLGSKKSVEGLE 269
V +F E+ L VRH E+ LVG++H+G+G D G++K+ G++
Sbjct: 65 MVVHSKFTRPGWRPGAERAPLGDLVRHAEHFAALVGWEHLGLGSDLDGGFGAEKTPAGID 124
Query: 270 DESKIPALIDTLNEK 284
+ +D L ++
Sbjct: 125 RYRDLTRFLDLLPQE 139
>pir||C83347 probable dipeptidase precursor PA2393 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9948434|gb|AAG05781.1|AE004665_8 (AE004665) probable
dipeptidase precursor [Pseudomonas aeruginosa]
Length = 448
Score = 75.3 bits (182), Expect = 8e-13
Identities = 49/154 (31%), Positives = 81/154 (51%), Gaps = 10/154 (6%)
Query: 89 EGKVALWLGMEGGEPI-ESLDILEIFHSMGLRVLTLTWSLRNQIGDG-----VFERTK-- 140
EGK A+ + M P+ + L L+ + + G+R+ + N D F T
Sbjct: 159 EGKFAIVMSMLNAYPLGDDLSQLDKWAARGVRMFGFNYVGNNDWSDSSRPLPFFNDTADA 218
Query: 141 -GGLTNFGAEVVGKCEELGIIVDVSHINEQGFWDVLDITAFPVIASHSNAKALCDHVRNL 199
GGL+ G + V + +LG+I+DVS ++ + V ++ P++ASHS +AL D RNL
Sbjct: 219 LGGLSPLGKQAVERLNDLGVIIDVSQMSTKALEQVAALSRAPIVASHSAPRALVDIKRNL 278
Query: 200 TDDQIKAIAERDGVIGAVAIPEFV-DKEKPTLEK 232
+D +++ I + GVI V P ++ KPTL+K
Sbjct: 279 SDHEMQLIKDSGGVIQVVGFPAYLRPLSKPTLDK 312
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.140 0.403
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112986613
Number of Sequences: 2977
Number of extensions: 4828305
Number of successful extensions: 11642
Number of sequences better than 1.0e-10: 36
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 11529
Number of HSP's gapped (non-prelim): 39
length of query: 307
length of database: 189,106,746
effective HSP length: 55
effective length of query: 252
effective length of database: 156,189,961
effective search space: 39359870172
effective search space used: 39359870172
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)