BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2389 (idsA-like) DE:bifunctional short chain isoprenyl
diphosphate synthase (idsA)
(346 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75139 bifunctional short chain isoprenyl diphosphate synth... 683 0.0
pir||E71101 probable geranylgeranyl pyrophosphate synthetase - P... 590 e-168
sp|O26156|IDSA_METTH BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPH... 287 2e-76
sp|Q53479|IDSA_METTM BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPH... 285 5e-76
sp|Q58270|IDSA_METJA BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPH... 277 1e-73
pir||T47275 geranylgeranyl diphosphate synthase [validated] - Ar... 274 9e-73
gi|11499867 bifunctional short chain isoprenyl diphosphate synth... 274 9e-73
gb|AAK40423.1| Geranylgeranyl pyrophosphate synthetase (gdS-1) ... 241 1e-62
gb|AAG19532.1| (AE005044) geranylgeranyl diphosphate synthase; I... 240 2e-62
sp|P95999|GGPP_SULSO GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 238 5e-62
sp|P39464|GGPP_SULAC GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 233 2e-60
pir||B72560 probable geranyltranstransferase APE1764 - Aeropyrum... 208 1e-52
dbj|BAA88983.1| (AB025791) farnesylgeranyl diphosphate synthase ... 197 1e-49
sp|Q50727|GGPP_MYCTU PROBABLE GERANYLGERANYL PYROPHOSPHATE SYNTH... 179 5e-44
dbj|BAA82615.1| (AB016095) farnesyl, geranylgeranyl, geranylfarn... 176 2e-43
sp|P44916|ISPB_HAEIN OCTAPRENYL-DIPHOSPHATE SYNTHASE (OCTAPRENYL... 176 4e-43
pir||T10452 farnesyltranstransferase (EC 2.5.1.29) precursor, ch... 174 1e-42
sp|P80042|GGPP_CAPAN GERANYLGERANYL PYROPHOSPHATE SYNTHETASE, CH... 174 1e-42
gb|AAD08933.1| (AC005724) putative geranylgeranyl pyrophosphate ... 173 2e-42
emb|CAB16803.1| (Z99708) geranylgeranyl pyrophosphate synthase [... 172 6e-42
dbj|BAA82613.1| (AB016093) geranylgeranyl diphosphate synthase (... 171 8e-42
pir||T11021 farnesyltranstransferase (EC 2.5.1.29) - white lupin... 171 1e-41
dbj|BAB02387.1| (AB023038) geranylgeranyl pyrophosphate synthase... 171 1e-41
pir||S74538 geranylgeranyl pyrophosphate synthase - Synechocysti... 170 2e-41
dbj|BAB02385.1| (AB023038) geranylgeranyl pyrophosphate synthase... 169 3e-41
dbj|BAA32241.1| (AB006850) decaprenyl diphosphate synthase [Gluc... 169 4e-41
gi|11467424 CrtE [Cyanophora paradoxa] >gi|1345836|sp|P48368|CRT... 168 7e-41
sp|P31114|HEP2_BACSU HEPTAPRENYL DIPHOSPHATE SYNTHASE COMPONENT ... 167 2e-40
sp|P19641|ISPB_ECOLI OCTAPRENYL-DIPHOSPHATE SYNTHASE (OCTAPRENYL... 166 3e-40
sp|P34802|GGPP_ARATH GERANYLGERANYL PYROPHOSPHATE SYNTHETASE, CH... 166 3e-40
pir||T35403 probable polyprenyl synthatase - Streptomyces coelic... 166 3e-40
dbj|BAA19583.1| (D85029) geranylgeranyl pyrophosphate synthase [... 166 3e-40
pir||T02429 geranylgeranyl pyrophosphate synthase (EC 2.5.1.-) -... 166 3e-40
dbj|BAA99946.1| (AP001309) geranylgeranyl pyrophosphate synthase... 166 5e-40
dbj|BAB01936.1| (AP002033) geranylgeranyl pyrophosphate synthase... 165 8e-40
gb|AAD16018.1| (AF081514) geranylgeranyl diphosphate synthase [T... 164 1e-39
gb|AAG10424.1| (AF251012) GGDP synthase [Tagetes erecta] 164 2e-39
sp|P55785|HEP2_BACST HEPTAPRENYL DIPHOSPHATE SYNTHASE COMPONENT ... 163 2e-39
pir||S71230 geranylgeranyl pyrophosphate synthase (EC 2.5.1.-) 2... 162 5e-39
dbj|BAA86284.1| (AB034249) geranylgeranyl pyrophosphate synthase... 162 5e-39
pir||T09966 farnesyltranstransferase (EC 2.5.1.29) - Madagascar ... 162 7e-39
gb|AAD12206.1| (AC006135) putative geranylgeranyl pyrophosphate ... 162 7e-39
gb|AAD47627.1| (AF153713) octylprenyl diphosphate synthase-like ... 161 9e-39
pir||A82688 octaprenyl-diphosphate synthase XF1391 [imported] - ... 161 9e-39
dbj|BAA86285.1| (AB034250) geranylgeranyl pyrophosphate synthase... 160 2e-38
pir||E70549 probable heptaprenyl diphosphate syntetase - Mycobac... 159 3e-38
sp|O66126|ISPA_MICLU GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHA... 159 3e-38
sp|Q08291|ISPA_BACST GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHA... 159 6e-38
gb|AAC77874.1| (AF020041) geranylgeranyl pyrophosphate synthase ... 159 6e-38
dbj|BAA22867.1| (AB001997) solanesyl diphosphate synthase [Rhodo... 158 8e-38
dbj|BAA78047.1| (AB027706) GGPP synthase [Daucus carota] 157 2e-37
pir||A81213 octaprenyl-diphosphate synthase (EC 2.5.1.-) NMA2161... 157 2e-37
gb|AAF08793.1|AF182828_1 (AF182828) geranyl diphosphate synthase... 157 2e-37
emb|CAC05969.1| (AL391763) polyprenyl synthetase [Streptomyces c... 157 2e-37
pir||C83075 octaprenyl-diphosphate synthase PA4569 [imported] - ... 156 3e-37
dbj|BAB05372.1| (AP001512) heptaprenyl diphosphate synthase comp... 156 4e-37
pir||F70973 probable transferase - Mycobacterium tuberculosis (s... 155 5e-37
pir||A70377 octoprenyl-diphosphate synthase - Aquifex aeolicus >... 155 5e-37
dbj|BAB01876.1| (AP000383) geranyl geranyl pyrophosphate synthas... 155 7e-37
pir||A82267 geranyltranstransferase VC0890 [imported] - Vibrio c... 155 9e-37
dbj|BAB07816.1| (AB037907) geranyl geranyl diphosphate synthase ... 155 9e-37
emb|CAC08284.1| (AL392148) putative transferase [Streptomyces co... 154 1e-36
gb|AAD50025.1|AC007651_20 (AC007651) Very similar to prenyl tran... 154 1e-36
dbj|BAA78046.1| (AB027705) GGPP synthase [Daucus carota] 154 1e-36
sp|P54383|ISPA_BACSU GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHA... 152 6e-36
emb|CAC11578.1| (AL445064) bifunctional short chain isoprenyl di... 152 8e-36
dbj|BAB06500.1| (AP001516) geranyltranstransferase [Bacillus hal... 151 1e-35
dbj|BAA82614.1| (AB016094) farnesyl diphosphate synthase (SelFPS... 150 3e-35
gb|AAF12843.1|AF203881_16 (AF203881) geranyltransferase [Zymomon... 149 4e-35
sp|P45204|ISPA_HAEIN GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHA... 149 5e-35
sp|O66952|ISPA_AQUAE GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHA... 149 5e-35
gb|AAD38295.1|AC007789_21 (AC007789) putative geranylgeranyl pyr... 149 5e-35
gb|AAD30584.1|AC007260_15 (AC007260) lcl|prt_seq No definition l... 148 9e-35
pir||B75457 polyprenyl synthase - Deinococcus radiodurans (strai... 146 3e-34
gi|11465734 prenyl transferase [Porphyra purpurea] >gi|1709766|s... 146 3e-34
sp|P22939|ISPA_ECOLI GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHA... 146 4e-34
pir||A82322 octaprenyl-diphosphate synthase VC0434 [imported] - ... 145 6e-34
gb|AAD43148.1|AC007504_3 (AC007504) geranyl geranyl pyrophosphat... 145 7e-34
pir||F83139 geranyltranstransferase PA4043 [imported] - Pseudomo... 144 1e-33
gi|11467329 prenyl transferase [Cyanophora paradoxa] >gi|399307|... 143 2e-33
pir||D71651 octaprenyl-diphosphate synthase (ispB) RP479 - Ricke... 143 2e-33
dbj|BAA23157.1| (AB000835) geranyl geranyl pyrophosphate synthas... 142 5e-33
dbj|BAA25268.1| (AB003188) component B of hexaprenyl diphosphate... 142 6e-33
pir||G72410 geranyltranstransferase - Thermotoga maritima (strai... 141 8e-33
pir||T50879 phytoene synthase [imported] - Rubrivivax gelatinosu... 140 2e-32
pir||D82778 geranyltranstransferase (farnesyl-diphosphate syntha... 140 2e-32
pir||E81796 geranyltranstransferase (EC 2.5.1.10) NMA2226 [impor... 140 2e-32
gb|AAF25540.1|AF104994_10 (AF104994) geranyl transferase [Strept... 139 4e-32
pir||T05674 farnesyltranstransferase homolog F20M13.20 - Arabido... 138 1e-31
dbj|BAA96457.1| (AB028044) farnesyl diphosphate synthase [Rhodob... 138 1e-31
pir||E81400 polyprenyl synthetase (EC 2.5.1.-) Cj0541 [imported]... 137 2e-31
gb|AAB41847.1| (U61168) spore germination protein C3 [Bacillus f... 136 5e-31
gb|AAA81879.1| (L40577) geranylgeranyl pyrophosphate synthase-re... 135 6e-31
pir||S76966 geranylgeranyl pyrophosphate synthase crtE homolog -... 135 6e-31
dbj|BAA96458.1| (AB028046) farnesyl diphosphate synthase [Rhodob... 135 8e-31
gb|AAG20290.1| (AE005103) putative isopentenyl pyrophosphate iso... 135 8e-31
pir||F81217 geranyltranstransferase NMB0261 [imported] - Neisser... 131 1e-29
gi|11465411 unknown; prenyl transferase [Cyanidium caldarium] >g... 129 4e-29
dbj|BAA96459.1| (AB028047) farnesyl diphosphate synthase [Rhodov... 129 5e-29
pir||C75400 geranylgeranyl diphosphate synthase - Deinococcus ra... 126 3e-28
gb|AAG28699.1|AF272737_2 (AF272737) CrtE [Streptomyces griseus] 125 7e-28
pir||T50750 farnesyltranstransferase (EC 2.5.1.29) crtE [importe... 123 2e-27
emb|CAC12434.1| (AL445067) geranylgeranyl pyrophosphate synthase... 123 4e-27
gi|7657653 trans-prenyltransferase; polyprenyl pyrophosphate syn... 122 5e-27
pir||B81261 geranyltranstransferase (EC 2.5.1.10) Cj1644 [import... 121 1e-26
pir||A70139 octaprenyl-diphosphate synthase (ispB) homolog - Lym... 120 2e-26
gi|9507201 trans-prenyltransferase [Mus musculus] >gi|4580645|gb... 118 9e-26
gb|AAF57135.1| (AE003777) CG3684 gene product [Drosophila melano... 118 1e-25
sp|P54976|CRTE_RHOSH GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 117 2e-25
gb|AAA91949.1| (L37405) geranylgeranyl pyrophosphate synthase [S... 117 2e-25
sp|P17060|CRTE_RHOCA GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 116 5e-25
gb|AAF78199.1|AF218415_1 (AF218415) geranylgeranyl synthase [Bra... 115 1e-24
gi|11499146 octaprenyl-diphosphate synthase (ispB) [Archaeoglobu... 113 4e-24
dbj|BAA16579.1| (D90899) prenyltransferase [Synechocystis sp.] 112 5e-24
emb|CAC16849.1| (Y17376) geranyl diphosphate synthase [Arabidops... 112 7e-24
pir||JC5429 di-trans,poly-cis-decaprenylcistransferase (EC 2.5.1... 110 3e-23
pir||G70935 probable idsA2 protein - Mycobacterium tuberculosis ... 110 3e-23
pir||H70600 probable transferase - Mycobacterium tuberculosis (s... 109 6e-23
pir||S32168 dimethylallyltranstransferase (EC 2.5.1.1) - Myxococ... 108 8e-23
sp|P21684|CRTE_PANAN GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 108 1e-22
pir||T51127 GGPP synthase [imported] - Brevibacterium linens >gi... 107 2e-22
gb|AAB37678.1| (U80443) Similar to hexaprenyl pyrophosphate synt... 106 3e-22
sp|Q45220|ISPA_BRAJA PROBABLE GERANYLTRANSTRANSFERASE (FARNESYL-... 104 2e-21
pir||S52584 crtE protein - Erwinia herbicola >gi|148394|gb|AAA21... 102 6e-21
pir||H64549 octaprenyl-diphosphate synthase - Helicobacter pylor... 102 8e-21
pir||D71959 probable octaprenyl-diphosphate synthase - Helicobac... 100 2e-20
sp|P55539|ISPA_RHISN PROBABLE GERANYLTRANSTRANSFERASE (FARNESYL-... 100 3e-20
sp|P57537|ISPA_BUCAI GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHA... 100 4e-20
emb|CAC16851.1| (AJ243739) geranyl diphosphate synthase [Citrus ... 99 5e-20
pir||C71295 probable octaprenyl-diphosphate synthase - syphilis ... 98 1e-19
dbj|BAA13462.1| (D87817) geranylgeranyl diphosphate synthetase [... 96 4e-19
sp|P22873|CRTE_ERWHE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 95 1e-18
pir||C72242 hypothetical protein TM1535 - Thermotoga maritima (s... 95 1e-18
pir||T43193 trans-pentaprenyltranstransferase homolog - fission ... 94 2e-18
pir||C39273 phytoene synthase - Erwinia herbicola 94 2e-18
emb|CAB75644.1| (AL157416) possible geranylgeranyl diphosphate s... 93 5e-18
emb|CAA05825.1| (AJ003049) IspA protein; partial [Wolinella succ... 89 7e-17
pir||E81650 geranylgeranyl pyrophosphate synthase, probable TC09... 89 7e-17
emb|CAB94793.1| (AJ133724) geranylgeranyl pyrophosphate synthase... 88 2e-16
dbj|BAA90525.1| (AB037600) geranylgeranyl diphosphate synthase [... 85 1e-15
sp|P24322|GGPP_NEUCR GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 80 5e-14
gb|AAC26705.1| (AC004077) putative trans-prenyltransferase [Arab... 79 8e-14
sp|Q92236|GGPP_GIBFU GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 76 6e-13
gb|AAC05273.1| (AF049659) geranylgeranyl pyrophosphate synthase ... 74 3e-12
gb|AAF50574.1| (AE003559) qm gene product [Drosophila melanogaster] 74 3e-12
emb|CAB57417.1| (AL121746) putative polyprenyl synthetase [Strep... 73 4e-12
gi|6325188 geranylgeranyl diphosphate synthase; Bts1p [Saccharom... 73 5e-12
gi|4758430 geranylgeranyl diphosphate synthase 1 [Homo sapiens] ... 73 5e-12
gi|11422894 geranylgeranyl diphosphate synthase 1 [Homo sapiens] 73 5e-12
gi|6806915 geranylgeranyl diphosphate synthase 1; GGPP synthase ... 73 6e-12
emb|CAA08919.1| (AJ009963) farnesyl pyrophosphate synthase [Dros... 71 2e-11
gb|AAD27853.1|AF132554_1 (AF132554) farnesyl pyrophosphate synth... 71 2e-11
sp|P56966|GGPP_BOVIN GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GG... 71 2e-11
pir||T06272 farnesyl-pyrophosphate synthetase FPS1 - tomato >gi|... 71 2e-11
emb|CAA59170.1| (X84695) dimethylallyltransferase [Capsicum annuum] 70 4e-11
pir||T23962 hypothetical protein R06C1.2 - Caenorhabditis elegan... 69 5e-11
pir||PV0010 hypothetical protein 131 (nlp 5' region) - Escherich... 69 7e-11
pir||T03687 farnesyl-pyrophosphate synthetase - rice >gi|2073375... 69 9e-11
gb|AAC05595.1| (AF049658) geranylgeranyl pyrophosphate synthase ... 69 9e-11
>pir||C75139 bifunctional short chain isoprenyl diphosphate synthase (idsa)
PAB2389 - Pyrococcus abyssi (strain Orsay)
>gi|5458339|emb|CAB49828.1| (AJ248285) bifunctional
short chain isoprenyl diphosphate synthase (idsA)
[Pyrococcus abyssi]
Length = 346
Score = 683 bits (1743), Expect = 0.0
Identities = 346/346 (100%), Positives = 346/346 (100%)
Query: 1 MKMGVGKYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLT 60
MKMGVGKYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLT
Sbjct: 1 MKMGVGKYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLT 60
Query: 61 ATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDL 120
ATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDL
Sbjct: 61 ATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDL 120
Query: 121 LFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISG 180
LFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISG
Sbjct: 121 LFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISG 180
Query: 181 KTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGS 240
KTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGS
Sbjct: 181 KTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGS 240
Query: 241 DIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKE 300
DIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKE
Sbjct: 241 DIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKE 300
Query: 301 HGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
HGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY
Sbjct: 301 HGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
>pir||E71101 probable geranylgeranyl pyrophosphate synthetase - Pyrococcus
horikoshii >gi|3257488|dbj|BAA30171.1| (AP000004) 342aa
long hypothetical geranylgeranyl pyrophosphate
synthetase [Pyrococcus horikoshii]
Length = 342
Score = 590 bits (1504), Expect = e-168
Identities = 281/340 (82%), Positives = 325/340 (94%)
Query: 7 KYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVG 66
KY+ELF RIKE+AKL+DEK+FELIPEK+P+VLYEAARHYPLAGGKR+RPFVVLT+TEAVG
Sbjct: 3 KYEELFARIKEKAKLIDEKIFELIPEKDPRVLYEAARHYPLAGGKRVRPFVVLTSTEAVG 62
Query: 67 GNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAF 126
G+ L+AIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVH++WG+NMAILAGDLLFSKAF
Sbjct: 63 GDPLRAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHRIWGVNMAILAGDLLFSKAF 122
Query: 127 EAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALF 186
EA++RAEI PEKKA+VLE IVKASNELCEGQA DLEFE + V+IEEYM MISGKTGALF
Sbjct: 123 EAVARAEIPPEKKARVLEVIVKASNELCEGQARDLEFEKKSTVTIEEYMEMISGKTGALF 182
Query: 187 DASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGK 246
+ASAKVGGI+GT+NEEYI+ALS WGRNVG+AFQIWDDVLDLIADE+KLGKPVGSDIRKGK
Sbjct: 183 EASAKVGGIIGTDNEEYIKALSSWGRNVGIAFQIWDDVLDLIADEKKLGKPVGSDIRKGK 242
Query: 247 KTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDY 306
KTLIVAHFFENADEK K++FLK+FGKYAGDVKG+GIIEED+K++VMEAI+LLK++GSIDY
Sbjct: 243 KTLIVAHFFENADEKDKQRFLKIFGKYAGDVKGRGIIEEDIKSDVMEAIDLLKKYGSIDY 302
Query: 307 ASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
A+ IA+++++KANEAL +LP+S+AR DLELLA F+VEREY
Sbjct: 303 AAEIAKDMIKKANEALRILPKSKARMDLELLAKFIVEREY 342
>sp|O26156|IDSA_METTH BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPHATE SYNTHASE [INCLUDES:
FARNESYL PYROPHOSPHATE SYNTHETASE (FPP SYNTHETASE)
(DIMETHYLALLYLTRANSFERASE); GERANYLTRANSTRANSFERASE ]
>gi|7447565|pir||G69165 bifunctional short chain
isoprenyl diphosphate synthase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621086|gb|AAB84557.1| (AE000797) bifunctional short
chain isoprenyl diphosphate synthase [Methanobacterium
thermoautotrophicum]
Length = 325
Score = 287 bits (726), Expect = 2e-76
Identities = 161/340 (47%), Positives = 223/340 (65%), Gaps = 20/340 (5%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA 69
E+ + +++ +++ DE++ E I + P+ L A+ H AGGK+IRP + L ++EAVGG+
Sbjct: 3 EVMDILRKYSEMADERIRESISDITPETLLRASEHLITAGGKKIRPSLALLSSEAVGGDP 62
Query: 70 LKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAI 129
A A AIELIH +SL+HDDIMD DE RRG+P VH +WG MAILAGD+LFSKAFEA+
Sbjct: 63 GDAAGVAAAIELIHTFSLIHDDIMDDDEIRRGEPAVHVLWGEPMAILAGDVLFSKAFEAV 122
Query: 130 SR---AEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALF 186
R +E+ E A V+++ VK +CEGQALD+ FE R V+ EEYM MI KT AL
Sbjct: 123 IRNGDSEMVKEALAVVVDSCVK----ICEGQALDMGFEERLDVTEEEYMEMIYKKTAALI 178
Query: 187 DASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGK 246
A+ K G I+G + + I AL +GR +G+AFQI DD LD+++DEE LGKPVGSDI +GK
Sbjct: 179 AAATKAGAIMGGGSPQEIAALEDYGRCIGLAFQIHDDYLDVVSDEESLGKPVGSDIAEGK 238
Query: 247 KTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDY 306
TL+V E A EK +E+ + + G +GD K V EAIE+ + +G+ +Y
Sbjct: 239 MTLMVVKALERASEKDRERLISILG--SGDEK-----------LVAEAIEIFERYGATEY 285
Query: 307 ASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
A +A + V A E L VL ES AR+ L ++A F++ERE+
Sbjct: 286 AHAVALDHVRMAKERLEVLEESDAREALAMIADFVLEREH 325
>sp|Q53479|IDSA_METTM BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPHATE SYNTHASE [INCLUDES:
FARNESYL PYROPHOSPHATE SYNTHETASE (FPP SYNTHETASE)
(DIMETHYLALLYLTRANSFERASE); GERANYLTRANSTRANSFERASE ]
>gi|11279236|pir||T45152 bifunctional short chain
isoprenyl diphosphate synthase [imported] -
Methanobacterium thermoautotrophicum
>gi|913252|gb|AAB32421.1| (S75695) bifunctional short
chain isoprenyl diphosphate synthase, IDSase,
FPP/GGPPSase=farnesyl diphosphate and geranylgeranyl
diphosphate synthase [Methanobacterium
thermoautotrophicum, Marburg, Peptide, 325 aa]
Length = 325
Score = 285 bits (722), Expect = 5e-76
Identities = 154/337 (45%), Positives = 218/337 (63%), Gaps = 14/337 (4%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA 69
E+ + +++ +++ D+++ E I + P L +A+ H AGGK+IRP + L + EAVGGN
Sbjct: 3 EVLDILRKYSEVADKRIMECISDITPDTLLKASEHLITAGGKKIRPSLALLSCEAVGGNP 62
Query: 70 LKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAI 129
A A AIELIH +SL+HDDIMD DE RRG+P+VH +WG MAILAGD+LFSKAFEA+
Sbjct: 63 EDAAGVAAAIELIHTFSLIHDDIMDDDEMRRGEPSVHVIWGEPMAILAGDVLFSKAFEAV 122
Query: 130 SRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDAS 189
R S E+ L +V + ++CEGQALD+ FE R V+ +EYM MI KT AL A+
Sbjct: 123 IRNGDS-ERVKDALAVVVDSCVKICEGQALDMGFEERLDVTEDEYMEMIYKKTAALIAAA 181
Query: 190 AKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTL 249
K G I+G +E +EAL +G+ +G+AFQI DD LD+++DEE LGKPVGSDI +GK TL
Sbjct: 182 TKAGAIMGGASEREVEALEDYGKFIGLAFQIHDDYLDVVSDEESLGKPVGSDIAEGKMTL 241
Query: 250 IVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASR 309
+V E A E+ +E+ + + G +GD + V EAIE+ + +G+ YA
Sbjct: 242 MVVKALEEASEEDRERLISILG--SGD-----------EGSVAEAIEIFERYGATQYAHE 288
Query: 310 IARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
+A + V A E L +L +S AR L +A F++ERE+
Sbjct: 289 VALDYVRMAKERLEILEDSDARDALMRIADFVLEREH 325
>sp|Q58270|IDSA_METJA BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPHATE SYNTHASE [INCLUDES:
FARNESYL PYROPHOSPHATE SYNTHETASE (FPP SYNTHETASE)
(DIMETHYLALLYLTRANSFERASE); GERANYLTRANSTRANSFERASE ]
>gi|2127782|pir||D64407 bifunctional short chain
isoprenyl diphosphate synthase homolog - Methanococcus
jannaschii >gi|1591545|gb|AAB98865.1| (U67530)
bifunctional short chain isoprenyl diphosphate synthase
(idsA) [Methanococcus jannaschii]
Length = 327
Score = 277 bits (702), Expect = 1e-73
Identities = 159/326 (48%), Positives = 220/326 (66%), Gaps = 20/326 (6%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIEL 81
+DE+L + +K+ K LY A++H AGGKRIRP++ + + + + A A+EL
Sbjct: 21 IDEELKTYV-DKDDK-LYNASKHLLFAGGKRIRPYLTVVTYMLKKDDIEEVLPAAAAVEL 78
Query: 82 IHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKA- 140
IHNY+L+HDDIMD D+ RRGKPTVH V+G MAILAGDLL++KAFEA+SR I KKA
Sbjct: 79 IHNYTLIHDDIMDNDDERRGKPTVHVVYGEPMAILAGDLLYAKAFEAVSR--IKDNKKAH 136
Query: 141 KVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTEN 200
+VL+ + KA E+CEGQA+D+EFEN ++EEY+ MI KTGAL +AS +G ++ N
Sbjct: 137 EVLKILSKACVEVCEGQAMDMEFENY-YPTMEEYLDMIRKKTGALLEASVGIGAVMADCN 195
Query: 201 EEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADE 260
EE EAL + + +G+ FQI DDVLDLI D++KLGKPVGSDIR+GKKT+IV H + DE
Sbjct: 196 EEEREALKEYAKRIGLTFQIQDDVLDLIGDQKKLGKPVGSDIREGKKTIIVIHALKTLDE 255
Query: 261 KAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANE 320
K++ L++ G K + +E++K EAIE+LK SI+YA + ++ E+A E
Sbjct: 256 DKKKRLLEILG-------NKNVKDEEIK----EAIEILKP--SIEYAKELMKQKTEEAKE 302
Query: 321 ALNVLPESRARKDLELLASFMVEREY 346
L + + R RK LE LA F++ R Y
Sbjct: 303 YLKIFNKDR-RKVLEDLADFIMSRIY 327
>pir||T47275 geranylgeranyl diphosphate synthase [validated] - Archaeoglobus
fulgidus >gi|4633648|gb|AAD26851.1| (AF120272)
geranylgeranyl diphosphate synthase [Archaeoglobus
fulgidus]
Length = 317
Score = 274 bits (694), Expect = 9e-73
Identities = 156/335 (46%), Positives = 216/335 (63%), Gaps = 20/335 (5%)
Query: 11 LFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNAL 70
L I +RA+++++ + EL+PE+EP LY+AARH AGGKR+RP + L A EA+G +
Sbjct: 2 LKEEIAKRAEIINKAIEELLPEREPIGLYKAARHLIKAGGKRLRPVISLLAVEALGKDYR 61
Query: 71 KAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAIS 130
K I AV+IE IHN++LVHDDIMD DE RRG PTVH+V+G AILAGD LF++AF+ ++
Sbjct: 62 KIIPAAVSIETIHNFTLVHDDIMDRDEMRRGVPTVHRVYGEATAILAGDTLFAEAFKLLT 121
Query: 131 RAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASA 190
+ ++ E K E + ++CEGQ D+ FE +E VS EEY+RM+ KTG L ASA
Sbjct: 122 KCDVESEGIRKATEMLSDVCIKICEGQYYDMSFEKKESVSEEEYLRMVELKTGVLIAASA 181
Query: 191 KVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLI 250
+ ++ E+EE ++AL +G G+ FQI DD+LDL E+ GK GSD+ KGKKTLI
Sbjct: 182 ALPAVLFGESEEIVKALWDYGVLSGIGFQIQDDLLDL---TEETGKDWGSDLLKGKKTLI 238
Query: 251 VAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRI 310
V FE K LK FGK DV +E+ + IE L+E G+IDYA+ +
Sbjct: 239 VIKAFE------KGVKLKTFGKEKADV-----------SEIRDDIEKLRECGAIDYAASM 281
Query: 311 ARELVEKANEALNVLPESRARKDLELLASFMVERE 345
AR++ E+A L VLPES+A++ L L F+V R+
Sbjct: 282 ARKMAEEAKRKLEVLPESKAKETLLELTDFLVTRK 316
>gi|11499867 bifunctional short chain isoprenyl diphosphate synthase (idsA)
{Methanobacterium thermoautotrophicum [Archaeoglobus
fulgidus] >gi|7447566|pir||F69535 bifunctional short
chain isoprenyl diphosphate synthase (idsA) homolog -
Archaeoglobus fulgidus >gi|2648237|gb|AAB88971.1|
(AE000947) bifunctional short chain isoprenyl
diphosphate synthase (idsA) {Methanobacterium
thermoautotrophicum [Archaeoglobus fulgidus]
Length = 326
Score = 274 bits (694), Expect = 9e-73
Identities = 156/335 (46%), Positives = 216/335 (63%), Gaps = 20/335 (5%)
Query: 11 LFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNAL 70
L I +RA+++++ + EL+PE+EP LY+AARH AGGKR+RP + L A EA+G +
Sbjct: 11 LKEEIAKRAEIINKAIEELLPEREPIGLYKAARHLIKAGGKRLRPVISLLAVEALGKDYR 70
Query: 71 KAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAIS 130
K I AV+IE IHN++LVHDDIMD DE RRG PTVH+V+G AILAGD LF++AF+ ++
Sbjct: 71 KIIPAAVSIETIHNFTLVHDDIMDRDEMRRGVPTVHRVYGEATAILAGDTLFAEAFKLLT 130
Query: 131 RAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASA 190
+ ++ E K E + ++CEGQ D+ FE +E VS EEY+RM+ KTG L ASA
Sbjct: 131 KCDVESEGIRKATEMLSDVCIKICEGQYYDMSFEKKESVSEEEYLRMVELKTGVLIAASA 190
Query: 191 KVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLI 250
+ ++ E+EE ++AL +G G+ FQI DD+LDL E+ GK GSD+ KGKKTLI
Sbjct: 191 ALPAVLFGESEEIVKALWDYGVLSGIGFQIQDDLLDL---TEETGKDWGSDLLKGKKTLI 247
Query: 251 VAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRI 310
V FE K LK FGK DV +E+ + IE L+E G+IDYA+ +
Sbjct: 248 VIKAFE------KGVKLKTFGKEKADV-----------SEIRDDIEKLRECGAIDYAASM 290
Query: 311 ARELVEKANEALNVLPESRARKDLELLASFMVERE 345
AR++ E+A L VLPES+A++ L L F+V R+
Sbjct: 291 ARKMAEEAKRKLEVLPESKAKETLLELTDFLVTRK 325
>gb|AAK40423.1| Geranylgeranyl pyrophosphate synthetase (gdS-1) [Sulfolobus
solfataricus]
Length = 332
Score = 241 bits (608), Expect = 1e-62
Identities = 136/341 (39%), Positives = 206/341 (59%), Gaps = 24/341 (7%)
Query: 8 YDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG 67
++E+ N + R K + F K L EA+ H AGGKR+RP V++++++ +GG
Sbjct: 10 FNEIVNNVNFRIKNFVKSNF--------KTLEEASFHLFTAGGKRLRPLVLVSSSDLIGG 61
Query: 68 NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
+ +A A A+E++HN++LVHDDIMD D RRG PTVH WG MAILAGD L +KAFE
Sbjct: 62 DRERAYKAAAAVEILHNFTLVHDDIMDNDGLRRGLPTVHVKWGEPMAILAGDYLHAKAFE 121
Query: 128 AISRA--EISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL 185
A++ A + K + + + EGQA+D+ FENR V+ EEY++MI GKT L
Sbjct: 122 ALNEALKGLDGNTFYKAFSIFITSIEIISEGQAMDMSFENRLDVTEEEYIQMIKGKTAML 181
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
F SA +GGI+ N++ ++ L+ +G N+G++FQI DD+L +I DE++LGKP+ SDIR+G
Sbjct: 182 FSCSAALGGIINKANDDVVKKLTEYGLNLGISFQIVDDILGIIGDEKELGKPIYSDIREG 241
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID 305
KKT++V A E K+ + G +E K ++ A E++++H S+
Sbjct: 242 KKTILVIKTLSEATEDEKKILVSTLGN-----------KEAKKEDLERASEIIRKH-SLQ 289
Query: 306 YASRIARELVEKANEALNVLPESR--ARKDLELLASFMVER 344
YA +A++ + A E L +P S A K L+ LA F ++R
Sbjct: 290 YAYDLAKKYSDLAIENLREIPVSNKTAEKALKYLAQFTIQR 330
>gb|AAG19532.1| (AE005044) geranylgeranyl diphosphate synthase; IdsA [Halobacterium
sp. NRC-1]
Length = 347
Score = 240 bits (606), Expect = 2e-62
Identities = 135/352 (38%), Positives = 205/352 (57%), Gaps = 38/352 (10%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVG-------- 66
++ER + V++ + + +P EP+ LYEA+R+ AGGKR+RP V+L EA+
Sbjct: 14 VRERRQQVNDAIDDDLPVAEPERLYEASRYILEAGGKRLRPAVLLLTAEALADTSDTPPY 73
Query: 67 -------GNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGD 119
G + + AV+IE+I +++L+HDDIMD D+ RRG P VH+ + AILAGD
Sbjct: 74 REFPDCIGGHVDVMSAAVSIEVIQSFTLIHDDIMDDDDLRRGSPAVHREYDTETAILAGD 133
Query: 120 LLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMIS 179
L+SKAFE + PE+ + + T+ + +CEGQA+D++FE R V +EY+ M+
Sbjct: 134 TLYSKAFEIMLETGAPPERGLRAMRTLAETCTHICEGQAMDIDFETRGDVVTDEYLEMVE 193
Query: 180 GKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVG 239
KT L+ A+A + G++ + +EE +EAL +G VG AFQI DDVLDL +LGK G
Sbjct: 194 LKTAVLYAAAATLPGLLLSADEETVEALYNYGLRVGQAFQIQDDVLDLTVPSAELGKQRG 253
Query: 240 SDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVME-----A 294
SD+ + K T+I H E+ V G+++ + A+V E A
Sbjct: 254 SDLVEDKTTIITLHAAEHG------------------VDVDGLLDAEDPADVTEAAVQAA 295
Query: 295 IELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
++ L++ GSI YAS +A +LVE+ L VLPE+ AR LE +A +++ER Y
Sbjct: 296 VQALQDAGSIQYASDLAEDLVEEGKAHLEVLPENEARHRLEQIADYLIERGY 347
>sp|P95999|GGPP_SULSO GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
[INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
>gi|7447562|pir||S75427 farnesyltranstransferase (EC
2.5.1.29) - Sulfolobus solfataricus
>gi|1707833|emb|CAA69541.1| (Y08257) geranylgeranyl
pyrophosphate synthetase [Sulfolobus solfataricus]
Length = 332
Score = 238 bits (602), Expect = 5e-62
Identities = 134/341 (39%), Positives = 206/341 (60%), Gaps = 24/341 (7%)
Query: 8 YDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG 67
++E+ N + R K + F K L EA+ H AGGKR+RP V++++++ +GG
Sbjct: 10 FNEIVNNVNFRIKNFVKSNF--------KTLEEASFHLFTAGGKRLRPLVLVSSSDLIGG 61
Query: 68 NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
+ +A A A+E++HN++LVHDDIMD D RRG PTVH WG MAILAGD L +KAFE
Sbjct: 62 DRERAYKAAAAVEILHNFTLVHDDIMDNDGLRRGLPTVHVKWGEPMAILAGDYLHAKAFE 121
Query: 128 AISRA--EISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL 185
+++ + + K + + + EGQA+D+ FENR V+ EEY++MI GKT L
Sbjct: 122 SLNESLKGLDGNTFYKAFSIFITSIEIISEGQAMDMSFENRLDVTEEEYIQMIKGKTAML 181
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
F SA +GGI+ N++ ++ L+ +G N+G++FQI DD+L +I DE++LGKP+ SDIR+G
Sbjct: 182 FSCSAALGGIINKANDDVVKKLTEYGLNLGISFQIVDDILGIIGDEKELGKPIYSDIREG 241
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID 305
KKT++V A E K+ + G +E K ++ A E++++H S+
Sbjct: 242 KKTILVIKTLSEATEDEKKILVSTLGN-----------KEAKKEDLERASEIIRKH-SLQ 289
Query: 306 YASRIARELVEKANEALNVLPESR--ARKDLELLASFMVER 344
YA +A++ + A E L +P S A K L+ LA F ++R
Sbjct: 290 YAYDLAKKYSDLAIENLREIPVSNKTAEKALKYLAQFTIQR 330
>sp|P39464|GGPP_SULAC GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
[INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
>gi|625954|pir||A54058 farnesyltranstransferase (EC
2.5.1.29) - Sulfolobus acidocaldarius
>gi|506371|dbj|BAA43200.1| (D28748) geranylgeranyl
diphosphate synthase [Sulfolobus acidocaldarius]
Length = 330
Score = 233 bits (588), Expect = 2e-60
Identities = 134/341 (39%), Positives = 204/341 (59%), Gaps = 20/341 (5%)
Query: 8 YDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG 67
+D FN I V++ + I PK LYEA+ H +GGKR+RP ++ +++ GG
Sbjct: 4 FDNYFNEI---VNSVNDIIKSYISGDVPK-LYEASYHLFTSGGKRLRPLILTISSDLFGG 59
Query: 68 NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
+A Y AIE++H ++LVHDDIMD D RRG PTVH +G+ +AILAGDLL +KAF+
Sbjct: 60 QRERAYYAGAAIEVLHTFTLVHDDIMDQDNIRRGLPTVHVKYGLPLAILAGDLLHAKAFQ 119
Query: 128 AISRA--EISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL 185
+++A + E K + ++ + EGQA+D+EFE+R + +EY+ MIS KT AL
Sbjct: 120 LLTQALRGLPSETIIKAFDIFTRSIIIISEGQAVDMEFEDRIDIKEQEYLDMISRKTAAL 179
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
F AS+ +G ++ N+ + +S +G N+G+AFQI DD+L L ADE++LGKPV SDIR+G
Sbjct: 180 FSASSSIGALIAGANDNDVRLMSDFGTNLGIAFQIVDDILGLTADEKELGKPVFSDIREG 239
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID 305
KKT++V E E K+ LK G + K E+M + +++K++ S+D
Sbjct: 240 KKTILVIKTLELCKEDEKKIVLKALGNKSAS-----------KEELMSSADIIKKY-SLD 287
Query: 306 YASRIARELVEKANEALNVLPESR--ARKDLELLASFMVER 344
YA +A + + A ++LN + K L+ LA F + R
Sbjct: 288 YAYNLAEKYYKNAIDSLNQVSSKSDIPGKALKYLAEFTIRR 328
>pir||B72560 probable geranyltranstransferase APE1764 - Aeropyrum pernix
(strain K1) >gi|5105454|dbj|BAA80767.1| (AP000062) 337aa
long hypothetical geranyltranstransferase [Aeropyrum
pernix]
Length = 337
Score = 208 bits (523), Expect = 1e-52
Identities = 126/352 (35%), Positives = 198/352 (55%), Gaps = 23/352 (6%)
Query: 1 MKMGVGKYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLT 60
M + V K+D LF + L+D + + + P L A+ H AGGKR+RP + L
Sbjct: 1 MGVSVLKWDRLFEASSRYSMLIDHYIMDFM-SITPDRLSGASLHLIKAGGKRLRPLITLL 59
Query: 61 ATEAVGG--NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAG 118
+GG +AI A +IE H +SL+HDDIMD DE RRG PT H V+G + AILAG
Sbjct: 60 TARMLGGLEAEARAIPLAASIETAHTFSLIHDDIMDRDEVRRGVPTTHVVYGDDWAILAG 119
Query: 119 DLLFSKAFEAISRAE---ISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYM 175
D L + AF+ I+ + +S E+ + + + +A+ ++ GQA D+ FE V + +Y+
Sbjct: 120 DTLHAAAFKMIADSREWGMSHEQAYRAFKVLSEAAIQISRGQAYDMLFEETWDVDVADYL 179
Query: 176 RMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLG 235
M+ KTGAL +A+A++G + E + + G N G+AFQI DD+L +I D + G
Sbjct: 180 NMVRLKTGALIEAAARIGAVAAGAGSEIEKMMGEVGMNAGIAFQIRDDILGVIGDPKVTG 239
Query: 236 KPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAI 295
KPV +D+R+GKKTL+V + + A + D+ G E+D+K A
Sbjct: 240 KPVYNDLRRGKKTLLVIYAVKKAGRRE-----------IVDLIGPKASEDDLK----RAA 284
Query: 296 ELLKEHGSIDYASRIARELVEKANEALNVLP--ESRARKDLELLASFMVERE 345
++ + G++DYA AR VE+A + L+ +P ++ +++ L LL ++VERE
Sbjct: 285 SIIVDSGALDYAESRARFYVERARDILSRVPAVDAESKELLNLLLDYIVERE 336
>dbj|BAA88983.1| (AB025791) farnesylgeranyl diphosphate synthase [Aeropyrum pernix]
Length = 318
Score = 197 bits (496), Expect = 1e-49
Identities = 117/317 (36%), Positives = 182/317 (56%), Gaps = 22/317 (6%)
Query: 35 PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG--NALKAIYPAVAIELIHNYSLVHDDI 92
P L A+ H AGGKR+RP + L +GG +AI A +IE H +SL+HDDI
Sbjct: 15 PDRLSGASLHLIKAGGKRLRPLITLLTARMLGGLEAEARAIPLAASIETAHTFSLIHDDI 74
Query: 93 MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE---ISPEKKAKVLETIVKA 149
MD DE RRG PT H V+G + AILAGD L + AF+ I+ + +S E+ + + + +A
Sbjct: 75 MDRDEVRRGVPTTHVVYGDDWAILAGDTLHAAAFKMIADSREWGMSHEQAYRAFKVLSEA 134
Query: 150 SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSR 209
+ ++ GQA D+ FE V + +Y+ M+ KTGAL +A+A++G + E + +
Sbjct: 135 AIQISRGQAYDMLFEETWDVDVADYLNMVRLKTGALIEAAARIGAVAAGAGSEIEKMMGE 194
Query: 210 WGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKV 269
G N G+AFQI DD+L +I D + GKPV +D+R+GKKTL+V + + A +
Sbjct: 195 VGMNAGIAFQIRDDILGVIGDPKVTGKPVYNDLRRGKKTLLVIYAVKKAGRRE------- 247
Query: 270 FGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLP--E 327
D+ G E+D+K A ++ + G++DYA AR VE+A + L+ +P +
Sbjct: 248 ----IVDLIGPKASEDDLK----RAASIIVDSGALDYAESRARFYVERARDILSRVPAVD 299
Query: 328 SRARKDLELLASFMVER 344
+ +++ L LL ++VER
Sbjct: 300 AESKELLNLLLDYIVER 316
>sp|Q50727|GGPP_MYCTU PROBABLE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(GGPPSASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE)
[INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
>gi|7447579|pir||C70735 probable idsA protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|1449389|emb|CAB01025.1| (Z77165) idsA [Mycobacterium
tuberculosis]
Length = 359
Score = 179 bits (449), Expect = 5e-44
Identities = 117/297 (39%), Positives = 164/297 (54%), Gaps = 11/297 (3%)
Query: 50 GKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVW 109
GK IRP +V A EA G + AI AV++EL+HN+SLVHDD+MD DE RR +PTV +W
Sbjct: 72 GKAIRPALVFVAAEAAGADPHSAIPGAVSVELVHNFSLVHDDLMDRDEHRRHRPTVWALW 131
Query: 110 GINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMV 169
G MA+LAGD + S A E + + SP A L I +A+ EL GQA D FE+R V
Sbjct: 132 GDAMALLAGDAMLSLAHEVLLDCD-SPHVGA-ALRAISEATRELIRGQAADTAFESRTDV 189
Query: 170 SIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIA 229
+++E ++M GKT AL ASA+VG ++ EAL +GR++G+AFQ+ DD+L +
Sbjct: 190 ALDECLKMAEGKTAALMAASAEVGALLAGAPRSVREALVAYGRHIGLAFQLVDDLLGIWG 249
Query: 230 DEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKA 289
E GKPV SD+R KKTL V + + + D G +D A
Sbjct: 250 RPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRR-----LAAWLVDETGSQTASDDELA 304
Query: 290 EVMEAIELLKEHGSIDYASRIARELVEKANEAL-NVLPESRARKDLELLASFMVERE 345
V E IE G +AS AR V + + + + R +L+ LA ++V+R+
Sbjct: 305 AVAELIEC---GGGRRWASAEARRHVTQGIDMVARIGIPDRPAAELQDLAHYIVDRQ 358
>dbj|BAA82615.1| (AB016095) farnesyl, geranylgeranyl, geranylfarnesyl, hexaprenyl,
heptaprenyl diphosphate synthase (SelF-HepPS)
[Synechococcus elongatus]
Length = 324
Score = 176 bits (443), Expect = 2e-43
Identities = 114/308 (37%), Positives = 162/308 (52%), Gaps = 18/308 (5%)
Query: 35 PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMD 94
P +L E R+ +GGKR+RP + L A EA G + A A A+E++HN++L+HDDIMD
Sbjct: 23 PPILDEPVRYALASGGKRLRPLITLLAAEACGSSPADAAPVAAAVEILHNFTLIHDDIMD 82
Query: 95 MDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR---AEISPEKKAKVLETIVKASN 151
RRG+PTV++ W AILAGD + A+ +S AE+ A+ V
Sbjct: 83 RSPLRRGRPTVYRAWDDATAILAGDTMMGIAYRLLSEHYPAEVCQHLVAECSSAFV---- 138
Query: 152 ELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWG 211
++C GQA DL F V++++Y+RMI KT LF +A GGIV + + AL +G
Sbjct: 139 DVCIGQAEDLAFRTMPSVTMDDYLRMIGRKTARLFATAAVAGGIVARAPHDVLAALRTYG 198
Query: 212 RNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFG 271
+GMAFQI DDVLDL E GK +G D+R+GKKT +A + L F
Sbjct: 199 TALGMAFQIRDDVLDLFGSPE-FGKELGQDLREGKKTFPTLSAAAHATD---PNDLATFA 254
Query: 272 KYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEAL-NVLPESRA 330
Y G D E+ + E + G++++A + + AN AL + LP + A
Sbjct: 255 AYFA-----GTPPTD-SEEIAQMRERCRRLGALEHAESLIAHYLSTANAALESHLPSTSA 308
Query: 331 RKDLELLA 338
R L LA
Sbjct: 309 RDRLCALA 316
>sp|P44916|ISPB_HAEIN OCTAPRENYL-DIPHOSPHATE SYNTHASE (OCTAPRENYL PYROPHOSPHATE
SYNTHETASE) (OPP SYNTHETASE) >gi|1074549|pir||I64160
hypothetical protein HI0881 - Haemophilus influenzae
(strain Rd KW20) >gi|1573899|gb|AAC22540.1| (U32770)
octaprenyl-diphosphate synthase (ispB) [Haemophilus
influenzae Rd]
Length = 329
Score = 176 bits (441), Expect = 4e-43
Identities = 103/299 (34%), Positives = 161/299 (53%), Gaps = 19/299 (6%)
Query: 49 GGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKV 108
GGKRIRP + + A ++G +I A +E IH SL+HDD++D + RRG+ T +
Sbjct: 49 GGKRIRPLIAVLAARSLGFEGSNSITCATFVEFIHTASLLHDDVVDESDMRRGRATANAE 108
Query: 109 WGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREM 168
+G ++L GD ++++AF+ +++ E K+L + A+N L EG+ L N
Sbjct: 109 FGNAASVLVGDFIYTRAFQLVAQLE-----SLKILSIMADATNVLAEGEVQQLMNVNDPE 163
Query: 169 VSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLI 228
S YMR+I KT LF+ + + IV E +AL +GR +G AFQ+ DDVLD
Sbjct: 164 TSEANYMRVIYSKTARLFEVAGQAAAIVAGGTEAQEKALQDYGRYLGTAFQLVDDVLDYS 223
Query: 229 ADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVK 288
A+ + LGK VG D+ +GK TL + H + + + + IE+ K
Sbjct: 224 ANTQALGKNVGDDLAEGKPTLPLLHAMRHGNAQQAALI-------------REAIEQGGK 270
Query: 289 AEVM-EAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
E + E + ++ EH S+DYA A+E +KA +A+ +LPES ++ L LA V+R Y
Sbjct: 271 REAIDEVLAIMTEHKSLDYAMNRAKEEAQKAVDAIEILPESEYKQALISLAYLSVDRNY 329
>pir||T10452 farnesyltranstransferase (EC 2.5.1.29) precursor, chloroplast -
white mustard >gi|1419758|emb|CAA67330.1| (X98795)
geranylgeranyl pyrophosphate synthase [Sinapis alba]
Length = 366
Score = 174 bits (437), Expect = 1e-42
Identities = 99/248 (39%), Positives = 151/248 (59%), Gaps = 9/248 (3%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA 69
+ + I +A V++ L +P +EP ++EA R+ LAGGKR+RP + + A E VGG
Sbjct: 71 DFMSYIIRKADSVNKALDSAVPLREPLKIHEAMRYSLLAGGKRVRPVLCIAACELVGGEE 130
Query: 70 LKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
A+ A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++A+LAGD L S AFE
Sbjct: 131 SLAMPARCAVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVYGEDVAVLAGDALLSFAFE 190
Query: 128 AISRA---EISPEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMISG 180
++ A E+SP + + + + KA + L GQ +D+ E ++ V +E +
Sbjct: 191 HLASATSSEVSPARVVRAVGELAKAIGTEGLVAGQVVDISSEGLDLNNVGLEHLKFIHLH 250
Query: 181 KTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGS 240
KT AL +ASA +GGI+G ++E IE L ++ R +G+ FQ+ DD+LD+ ++LGK G
Sbjct: 251 KTAALLEASAVLGGIIGGGSDEEIERLRKFARCIGLLFQVVDDILDVTKSSQELGKTAGK 310
Query: 241 DIRKGKKT 248
D+ K T
Sbjct: 311 DLIADKLT 318
>sp|P80042|GGPP_CAPAN GERANYLGERANYL PYROPHOSPHATE SYNTHETASE, CHLOROPLAST PRECURSOR
(GGPP SYNTHETASE) [INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
>gi|1076576|pir||S53722 farnesyltranstransferase (EC
2.5.1.29) precursor - pepper >gi|643094|emb|CAA56554.1|
(X80267) geranylgeranyl diphosphate synthase [Capsicum
annuum]
Length = 369
Score = 174 bits (437), Expect = 1e-42
Identities = 104/256 (40%), Positives = 149/256 (57%), Gaps = 6/256 (2%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIY 74
+ E+A V++ L E I KEP V++EA R+ LAGGKR+RP + L A E VGGN A+
Sbjct: 82 VTEKAISVNKALDEAIIVKEPHVIHEAMRYSLLAGGKRVRPMLCLAACELVGGNQENAMA 141
Query: 75 PAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAI--S 130
A A+E+IH SL+HDD+ MD D+ RRGKPT HK++G ++A+LAGD L + AFE I S
Sbjct: 142 AACAVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKIYGEDVAVLAGDSLLAFAFEHIVNS 201
Query: 131 RAEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDA 188
A ++P + + + K+ + L GQ D++ VS+E + KT AL ++
Sbjct: 202 TAGVTPSRIVGAVAELAKSIGTEGLVAGQVADIKCTGNASVSLETLEFIHVHKTAALLES 261
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
S +G I+G +E L R+ R +G+ FQ+ DD+LD+ E+LGK G D+ K T
Sbjct: 262 SVVLGAILGGGTNVEVEKLRRFARCIGLLFQVVDDILDVTKSSEELGKTAGKDLVVDKTT 321
Query: 249 LIVAHFFENADEKAKE 264
E A E A E
Sbjct: 322 YPKLLGLEKAKEFAAE 337
>gb|AAD08933.1| (AC005724) putative geranylgeranyl pyrophosphate synthase
[Arabidopsis thaliana]
Length = 372
Score = 173 bits (435), Expect = 2e-42
Identities = 98/237 (41%), Positives = 145/237 (60%), Gaps = 6/237 (2%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ ++ L E IP EP +++A R+ LAGGKR+RP + L A E VGG AI A
Sbjct: 88 KAETINRALDEAIPLIEPLNIHKAMRYAILAGGKRVRPILCLAACELVGGEERLAIQAAC 147
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEIS 135
A+E+IH SL+ DD+ MD D+ RRGKPT HKV+G ++AIL+G L + AFE ++ A++S
Sbjct: 148 AVEMIHTMSLIKDDLPCMDNDDLRRGKPTTHKVFGESVAILSGGALLALAFEHLTEADVS 207
Query: 136 PEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMISGKTGALFDASAK 191
+K + ++ + K+ + L GQA DL E E V +E+ + KTG+L +ASA
Sbjct: 208 SKKMVRAVKELAKSIGTKGLVAGQAKDLSSEGLEQNDVGLEDLEYIHVHKTGSLLEASAV 267
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G ++G E+ IE + + R +G+ FQ+ DD+LD E+LGK G D GK T
Sbjct: 268 IGAVIGGGTEKEIEKVRNFARCIGLLFQVVDDILDETKSSEELGKTAGKDKVAGKLT 324
>emb|CAB16803.1| (Z99708) geranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana] >gi|7270630|emb|CAB80347.1| (AL161590)
geranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 371
Score = 172 bits (431), Expect = 6e-42
Identities = 99/249 (39%), Positives = 152/249 (60%), Gaps = 10/249 (4%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA 69
+ + I +A+LV++ L +P +EP ++EA R+ LAGGKR+RP + + A E VGG
Sbjct: 75 DFMSYIITKAELVNKALDSAVPLREPLKIHEAMRYSLLAGGKRVRPVLCIAACELVGGEE 134
Query: 70 LKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
A+ A A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++A+LAGD L S AFE
Sbjct: 135 STAMPAACAVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVFGEDVAVLAGDALLSFAFE 194
Query: 128 AISRAE----ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMIS 179
++ A +SP + + + + KA + L GQ +D+ E ++ V +E +
Sbjct: 195 HLASATSSDVVSPVRVVRAVGELAKAIGTEGLVAGQVVDISSEGLDLNDVGLEHLEFIHL 254
Query: 180 GKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVG 239
KT AL +ASA +G IVG +++ IE L ++ R +G+ FQ+ DD+LD+ ++LGK G
Sbjct: 255 HKTAALLEASAVLGAIVGGGSDDEIERLRKFARCIGLLFQVVDDILDVTKSSKELGKTAG 314
Query: 240 SDIRKGKKT 248
D+ K T
Sbjct: 315 KDLIADKLT 323
>dbj|BAA82613.1| (AB016093) geranylgeranyl diphosphate synthase (SelGGPS)
[Synechococcus elongatus]
Length = 307
Score = 171 bits (430), Expect = 8e-42
Identities = 102/242 (42%), Positives = 144/242 (59%), Gaps = 10/242 (4%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIY 74
+KER LV+ L IP P+ +Y+A R+ +AGGKR+RP + L E +GG A+
Sbjct: 21 LKERQALVEAALEASIPVAYPEKIYDAMRYSLMAGGKRLRPILCLATCELMGGTVEMAMP 80
Query: 75 PAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRA 132
A A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++AILAGD L + AFE +
Sbjct: 81 TACALEMIHTMSLIHDDLPAMDNDDYRRGKPTNHKVYGEDIAILAGDGLLAYAFEYV--V 138
Query: 133 EISPEKKAKVLETIVK------ASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALF 186
E + A+ L IV A+ L GQ +DLE E + + +E + S KTGAL
Sbjct: 139 EQTKNVPAEYLLKIVARLGHAVAATGLVGGQVVDLECEGQPDIGLETLHFIHSHKTGALL 198
Query: 187 DASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGK 246
+AS G ++ +E + LSR+ N+G+AFQI DD+LD+ + + LGK VG D+ K
Sbjct: 199 EASVVSGALLTGAHESDVARLSRYAANIGLAFQIVDDILDITSTRDVLGKTVGKDVAAQK 258
Query: 247 KT 248
T
Sbjct: 259 MT 260
>pir||T11021 farnesyltranstransferase (EC 2.5.1.29) - white lupine
>gi|558925|gb|AAA86688.1| (U15778) geranylgeranyl
pyrophosphate synthase [Lupinus albus]
Length = 316
Score = 171 bits (429), Expect = 1e-41
Identities = 99/254 (38%), Positives = 152/254 (58%), Gaps = 6/254 (2%)
Query: 17 ERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPA 76
E+++ V++ L + + +EP ++EA R+ LAGGKR+RP + + A E VGGN A+ A
Sbjct: 31 EKSRSVNQALNDAVSLREPHKIHEAMRYSLLAGGKRVRPVLCIAACEVVGGNESTAMAAA 90
Query: 77 VAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE--AISRA 132
+IE+IH SL+HDD+ MD D+ RRGKPT HKV+G N+A+LAGD L + AFE A+S +
Sbjct: 91 CSIEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVFGENIAVLAGDALLAFAFEHIAVSTS 150
Query: 133 EISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASA 190
+SPE+ + + K+ + L GQ +D+ E + +E+ + KT AL + S
Sbjct: 151 GVSPERIIGAIGELAKSIGTEGLVAGQVVDINSEGLCDIGLEKLEFIHLHKTAALLEGSV 210
Query: 191 KVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLI 250
VG I+G E +E L + R +G+ FQ+ DDVLD+ ++LGK G D+ K T
Sbjct: 211 VVGAILGGGCNEEVEKLRMFARYIGLMFQVVDDVLDVTKSSKELGKTAGKDLVADKVTYP 270
Query: 251 VAHFFENADEKAKE 264
E ++E A++
Sbjct: 271 KLLGIEKSNEFAQK 284
>dbj|BAB02387.1| (AB023038) geranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 360
Score = 171 bits (428), Expect = 1e-41
Identities = 98/240 (40%), Positives = 145/240 (59%), Gaps = 9/240 (3%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ V+ L +P +EP + EA R+ LAGGKR+RP + + E VGG+ A+ A
Sbjct: 73 KAESVNAALDVSVPLREPLTVQEAVRYSLLAGGKRVRPLLCIAVCELVGGDEATAMSAAC 132
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE---AISRA 132
A+E+IH SL+HDD+ MD + RRGKPT HKV+G +MA+LAGD L + AFE +S
Sbjct: 133 AVEMIHTSSLIHDDLPCMDNADLRRGKPTNHKVYGEDMAVLAGDALLALAFEHMTVVSSG 192
Query: 133 EISPEKKAKVLETIVKA--SNELCEGQALDLEFE--NREMVSIEEYMRMISGKTGALFDA 188
++PE+ + + + +A + L GQ +DL E N + V +E + KT AL +A
Sbjct: 193 LVAPERMIRAVVELARAIGTTGLVAGQMIDLASERLNPDKVGLEHLEFIHLHKTAALLEA 252
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+A +G I+G EE IE L ++ R +G+ FQ+ DD+LD+ E+LGK G D+ GK T
Sbjct: 253 AAVLGVIMGGGTEEEIEKLRKYARCIGLLFQVVDDILDVTKSTEELGKTAGKDVMAGKLT 312
>pir||S74538 geranylgeranyl pyrophosphate synthase - Synechocystis sp. (strain
PCC 6803) >gi|1651762|dbj|BAA16690.1| (D90899)
geranylgeranyl pyrophosphate synthase [Synechocystis
sp.]
Length = 302
Score = 170 bits (426), Expect = 2e-41
Identities = 97/245 (39%), Positives = 147/245 (59%), Gaps = 6/245 (2%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA 69
+L ++ + +V+ L + P+ +YEA R+ LAGGKR+RP + +TA E GG+
Sbjct: 11 DLAQYLQVKKGVVEAALDSSLAIARPEKIYEAMRYSLLAGGKRLRPILCITACELCGGDE 70
Query: 70 LKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
A+ A A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++AILAGD L + AFE
Sbjct: 71 ALALPTACALEMIHTMSLIHDDLPSMDNDDFRRGKPTNHKVYGEDIAILAGDGLLAYAFE 130
Query: 128 AI--SRAEISPEKKAKVLETIVKASNE--LCEGQALDLEFENREMVSIEEYMRMISGKTG 183
+ + P+ +V+ + + L GQ LDLE E R ++ E + + KTG
Sbjct: 131 YVVTHTPQADPQALLQVIARLGRTVGAAGLVGGQVLDLESEGRTDITPETLTFIHTHKTG 190
Query: 184 ALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIR 243
AL +AS G I+ E + L+R+ +N+G+AFQ+ DD+LD+ A +E+LGK G D++
Sbjct: 191 ALLEASVLTGAILAGATGEQQQRLARYAQNIGLAFQVVDDILDITATQEELGKTAGKDVK 250
Query: 244 KGKKT 248
K T
Sbjct: 251 AQKAT 255
>dbj|BAB02385.1| (AB023038) geranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 360
Score = 169 bits (425), Expect = 3e-41
Identities = 98/240 (40%), Positives = 145/240 (59%), Gaps = 9/240 (3%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ V+ L +P +P + EA R+ LAGGKR+RP + + A E VGG+ A+ A
Sbjct: 73 KAESVNAALDVSVPLLKPLTIQEAVRYSLLAGGKRVRPLLCIAACELVGGDEATAMSAAC 132
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE---AISRA 132
A+E+IH SL+HDD+ MD + RRGKPT HKV+G +MA+LAGD L + AFE +S
Sbjct: 133 AVEMIHTSSLIHDDLPCMDNADLRRGKPTNHKVYGEDMAVLAGDALLALAFEHMTVVSSG 192
Query: 133 EISPEKKAKVLETIVKA--SNELCEGQALDLEFE--NREMVSIEEYMRMISGKTGALFDA 188
++PEK + + + +A + L GQ +DL E N + V +E + KT AL +A
Sbjct: 193 LVAPEKMIRAVVELARAIGTTGLVAGQMIDLASERLNPDKVGLEHLEFIHLHKTAALLEA 252
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+A +G I+G E+ IE L ++ R +G+ FQ+ DD+LD+ E+LGK G D+ GK T
Sbjct: 253 AAVLGVIMGGGTEQEIEKLRKYARCIGLLFQVVDDILDVTKSTEELGKTAGKDVMAGKLT 312
>dbj|BAA32241.1| (AB006850) decaprenyl diphosphate synthase [Gluconobacter
suboxydans]
Length = 315
Score = 169 bits (424), Expect = 4e-41
Identities = 102/317 (32%), Positives = 167/317 (52%), Gaps = 20/317 (6%)
Query: 32 EKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVG----GNALKAIYPAVAIELIHNYSL 87
E ++ + H AGGKR+RP + L + G + + + A +E IH +L
Sbjct: 13 ESPVPLIPQLGAHLVAAGGKRLRPLLTLASARLCGYQPGPDHQRHVGLAACVEFIHTATL 72
Query: 88 VHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIV 147
+HDD++D RRG + + V+G ++L GD LF+++F+ ++ + KV+ +
Sbjct: 73 LHDDVVDESTLRRGLASANAVFGNKASVLVGDFLFARSFQLMTA-----DGSLKVMAILS 127
Query: 148 KASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEAL 207
AS + EG+ L + +N +E Y+ +I GKT ALF A+ +VG +V E EAL
Sbjct: 128 DASATIAEGEVLQMVVQNDLTTPVERYLEVIHGKTAALFAAACRVGAVVAERPEAEEEAL 187
Query: 208 SRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFL 267
R+G N+GMAFQ+ DD LD AD++ LGK VG D+R+GK TL V +E + + +
Sbjct: 188 ERFGTNLGMAFQLVDDALDYAADQQVLGKTVGDDMREGKITLPVLAAYEAGSPEDRIFWE 247
Query: 268 KVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPE 327
+V G+ E + ++ A+ L+ + G+I+ A+ + A EAL++ P+
Sbjct: 248 RVIGE-----------GEQTEDDLPHALNLIAKTGAINTTIARAQVYADAAVEALSIFPD 296
Query: 328 SRARKDLELLASFMVER 344
S R+ L F V R
Sbjct: 297 SELRRLLIETVQFTVNR 313
>gi|11467424 CrtE [Cyanophora paradoxa] >gi|1345836|sp|P48368|CRTE_CYAPA
GERANYLGERANYL PYROPHOSPHATE SYNTHETASE HOMOLOG (GGPP
SYNTHETASE) (FARNESYLTRANSTRANSFERASE)
>gi|7447351|pir||T06969 farnesyltranstransferase (EC
2.5.1.29) - Cyanophora paradoxa cyanelle
>gi|1016225|gb|AAA81312.1| (U30821) CrtE [Cyanophora
paradoxa]
Length = 300
Score = 168 bits (422), Expect = 7e-41
Identities = 95/244 (38%), Positives = 145/244 (58%), Gaps = 6/244 (2%)
Query: 11 LFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNAL 70
L + ER ++V++ L + IP P +Y++ R+ AGGKRIRP + L + E GG
Sbjct: 10 LLTYLYERKEIVEDTLNKSIPRGNPTFIYDSIRYSLSAGGKRIRPILCLASCELAGGTME 69
Query: 71 KAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEA 128
A+ A A+E+IH SL+HDD+ MD D RRGKPT H ++G ++AILAGD L + AFE
Sbjct: 70 MALPTACALEMIHTMSLIHDDLPAMDNDSYRRGKPTNHIIYGEDLAILAGDALLAYAFEF 129
Query: 129 ISRA--EISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGA 184
I+ + + KV+ + + ++ L GQ +DL E + ++E + KTGA
Sbjct: 130 IATQTKNVPADLIVKVIAQVAHSVTTSGLVGGQIIDLSSEGKSDTTLETLNFIHIHKTGA 189
Query: 185 LFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRK 244
L +A+ G ++ E+ + R+ +N+G+AFQI DDVLD+I+ EEKLGK +G D++
Sbjct: 190 LLEAAVLSGALLAGAKEKDMNRFLRYAQNIGLAFQIIDDVLDIISTEEKLGKSIGKDLKT 249
Query: 245 GKKT 248
K T
Sbjct: 250 QKAT 253
>sp|P31114|HEP2_BACSU HEPTAPRENYL DIPHOSPHATE SYNTHASE COMPONENT II (HEPPP SYNTHASE
SUBUNIT 2) (SPORE GERMINATION PROTEIN C3)
>gi|7447567|pir||E69630 heptaprenyl diphosphate synthase
component II gerCC - Bacillus subtilis
>gi|143803|gb|AAA20856.1| (M80245) GerC3 [Bacillus
subtilis] >gi|2634692|emb|CAB14190.1| (Z99115)
heptaprenyl diphosphate synthase component II [Bacillus
subtilis]
Length = 348
Score = 167 bits (418), Expect = 2e-40
Identities = 108/341 (31%), Positives = 182/341 (52%), Gaps = 23/341 (6%)
Query: 7 KYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVG 66
K+ ++ + + +++ +L + + P +L EA H AGGKRIRP VL +
Sbjct: 30 KFKMAYSFLNDDIDVIERELEQTVRSDYP-LLSEAGLHLLQAGGKRIRPVFVLLSGMFGD 88
Query: 67 GNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAF 126
+ K Y AV +E+IH SLVHDD++D E RRGKPT+ W +A+ GD + + +
Sbjct: 89 YDINKIKYVAVTLEMIHMASLVHDDVIDDAELRRGKPTIKAKWDNRIAMYTGDYMLAGSL 148
Query: 127 EAISRAEISPEKKAKVL-ETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL 185
E ++R I+ K ++L +TIV E+C G+ ++ + ++ Y+R I KT L
Sbjct: 149 EMMTR--INEPKAHRILSQTIV----EVCLGEIEQIKDKYNMEQNLRTYLRRIKRKTALL 202
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
S ++G I +E+ +AL +G VGM++QI DD+LD + EE+LGKPVG D+ +G
Sbjct: 203 IAVSCQLGAIASGADEKIHKALYWFGYYVGMSYQIIDDILDFTSTEEELGKPVGGDLLQG 262
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID 305
TL V + +N K + K + E + ++ IE +K+ +I+
Sbjct: 263 NVTLPVLYALKNPALKNQLKLIN---------------SETTQEQLEPIIEEIKKTDAIE 307
Query: 306 YASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
+ ++ ++KA + LN LP RAR L +A ++ +R++
Sbjct: 308 ASMAVSEMYLQKAFQKLNTLPRGRARSSLAAIAKYIGKRKF 348
>sp|P19641|ISPB_ECOLI OCTAPRENYL-DIPHOSPHATE SYNTHASE (OCTAPRENYL PYROPHOSPHATE
SYNTHETASE) (OPP SYNTHETASE) >gi|7447561|pir||E65109
octaprenyl-diphosphate synthase (EC 2.5.1.-) -
Escherichia coli >gi|606125|gb|AAA57988.1| (U18997)
ORF_o323 [Escherichia coli] >gi|1789578|gb|AAC76219.1|
(AE000399) octaprenyl diphosphate synthase [Escherichia
coli K12]
Length = 323
Score = 166 bits (417), Expect = 3e-40
Identities = 103/298 (34%), Positives = 161/298 (53%), Gaps = 19/298 (6%)
Query: 49 GGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKV 108
GGKRIRP + + A AVG + A IE IH +L+HDD++D + RRGK T +
Sbjct: 43 GGKRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA 102
Query: 109 WGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREM 168
+G ++L GD ++++AF+ ++ KVLE + +A N + EG+ L L N
Sbjct: 103 FGNAASVLVGDFIYTRAFQMMTSLG-----SLKVLEVMSEAVNVIAEGEVLQLMNVNDPD 157
Query: 169 VSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLI 228
++ E YMR+I KT LF+A+A+ GI+ E + L +GR +G AFQ+ DD+LD
Sbjct: 158 ITEENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYN 217
Query: 229 ADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVK 288
AD E+LGK VG D+ +GK TL + H + + + + IE+
Sbjct: 218 ADGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMI-------------RTAIEQGNG 264
Query: 289 AEVME-AIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVERE 345
++E +E + GS+++ + A E +KA AL VLP++ R+ L LA V+R+
Sbjct: 265 RHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRD 322
>sp|P34802|GGPP_ARATH GERANYLGERANYL PYROPHOSPHATE SYNTHETASE, CHLOROPLAST PRECURSOR
(GGPP SYNTHETASE) [INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
>gi|413730|gb|AAA32797.1| (L25813) geranylgeranyl
pyrophosphate synthase [Arabidopsis thaliana]
Length = 371
Score = 166 bits (417), Expect = 3e-40
Identities = 96/249 (38%), Positives = 150/249 (59%), Gaps = 10/249 (4%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA 69
+ + I +A+LV++ L +P +EP ++EA + LAGGKR+RP + + A E VGG
Sbjct: 75 DFMSYIITKAELVNKALDSAVPLREPLKIHEAMSYSLLAGGKRVRPVLCIAACELVGGEE 134
Query: 70 LKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
A+ A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++A+LAGD L S +FE
Sbjct: 135 STAMPARCAVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVFGEDVAVLAGDALLSFSFE 194
Query: 128 AISRAE----ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMIS 179
++ A +SP + + + + KA + L GQ +D+ E ++ V +E +
Sbjct: 195 HLASATSSDVVSPVRVVRAVGELAKAIGTEGLVAGQVVDISSEGLDLNDVGLEHLEFIHL 254
Query: 180 GKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVG 239
KT AL +ASA +G IVG +++ IE L ++ R +G+ FQ+ DD+LD+ ++LGK G
Sbjct: 255 HKTAALLEASAVLGAIVGGGSDDEIERLRKFARCIGLLFQVVDDILDVTKSSKELGKTAG 314
Query: 240 SDIRKGKKT 248
D+ K T
Sbjct: 315 KDLIADKLT 323
>pir||T35403 probable polyprenyl synthatase - Streptomyces coelicolor
>gi|4539167|emb|CAB39696.1| (AL049485) putative
polyprenyl synthatase [Streptomyces coelicolor A3(2)]
Length = 378
Score = 166 bits (416), Expect = 3e-40
Identities = 105/298 (35%), Positives = 160/298 (53%), Gaps = 8/298 (2%)
Query: 49 GGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKV 108
GGK +RP + + + E G + AVA+EL+HN+SL+HDD+MD DE RR + TV KV
Sbjct: 87 GGKAVRPALAVLSAEVTGAAPEVGVPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKV 146
Query: 109 WGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREM 168
G AIL GD LF+ A E + E+ + + + KAS L +GQA D+ +E+R+
Sbjct: 147 HGPAQAILVGDALFALANEVL--LELGTVEAGRATRRLTKASRSLIDGQAQDISYEHRDR 204
Query: 169 VSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLI 228
VS+EE + M KTGAL ++ +G ++G +E + L ++G ++G+AFQ DD+L +
Sbjct: 205 VSVEECLEMEGNKTGALLACASSIGAVLGGADERTADTLEKYGYHLGLAFQAVDDLLGIW 264
Query: 229 ADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVK 288
D + GK SD+R+ KK+L V A A E+ ++ A EE+
Sbjct: 265 GDPDATGKQTWSDLRQRKKSLPVVAALA-AGGAASERLGEILTADAKASDFANFSEEEFA 323
Query: 289 AEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLP-ESRARKDLELLASFMVERE 345
A L++E G ++ + AR A EAL+ + R R LA F+V R+
Sbjct: 324 ARA----ALIEEAGGREWTADEARRQHTIAIEALDAVDMPDRVRDRFTALADFVVVRK 377
>dbj|BAA19583.1| (D85029) geranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 373
Score = 166 bits (416), Expect = 3e-40
Identities = 95/237 (40%), Positives = 143/237 (60%), Gaps = 6/237 (2%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ V++ L E IP EP ++EA R+ LA GKR+RP + L + E VGG A+ A
Sbjct: 89 KAESVNKALEEAIPVGEPLKIHEAMRYAILAAGKRVRPILCLASCELVGGQENAAMPAAC 148
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEIS 135
A+E+IH SL+ DD+ MD D+ RRGKPT HKV+G +AIL+G L S AFE ++ AEIS
Sbjct: 149 AVEMIHTMSLIKDDLPCMDNDDLRRGKPTTHKVYGEGVAILSGGALLSLAFEHMTTAEIS 208
Query: 136 PEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMISGKTGALFDASAK 191
E+ + + ++ + L GQA+D+ E ++ V +E + KT L + +A
Sbjct: 209 SERMVWAVRELARSIGTRGLVAGQAMDISSEGLDLNEVGLEHLEFIHVHKTAVLLETAAV 268
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G I+G ++E IE++ ++ R +G+ FQ+ DD+LD E+LGK G D GK T
Sbjct: 269 LGAIIGGGSDEEIESVRKFARCIGLLFQVVDDILDETKSSEELGKTAGKDQLAGKLT 325
>pir||T02429 geranylgeranyl pyrophosphate synthase (EC 2.5.1.-) - Arabidopsis
thaliana >gi|3152604|gb|AAC17083.1| (AC004482)
pregeranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 376
Score = 166 bits (416), Expect = 3e-40
Identities = 95/237 (40%), Positives = 143/237 (60%), Gaps = 6/237 (2%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ V++ L E IP EP ++EA R+ LA GKR+RP + L + E VGG A+ A
Sbjct: 92 KAESVNKALEEAIPVGEPLKIHEAMRYAILAAGKRVRPILCLASCELVGGQENAAMPAAC 151
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEIS 135
A+E+IH SL+ DD+ MD D+ RRGKPT HKV+G +AIL+G L S AFE ++ AEIS
Sbjct: 152 AVEMIHTMSLIKDDLPCMDNDDLRRGKPTTHKVYGEGVAILSGGALLSLAFEHMTTAEIS 211
Query: 136 PEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMISGKTGALFDASAK 191
E+ + + ++ + L GQA+D+ E ++ V +E + KT L + +A
Sbjct: 212 SERMVWAVRELARSIGTRGLVAGQAMDISSEGLDLNEVGLEHLEFIHVHKTAVLLETAAV 271
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G I+G ++E IE++ ++ R +G+ FQ+ DD+LD E+LGK G D GK T
Sbjct: 272 LGAIIGGGSDEEIESVRKFARCIGLLFQVVDDILDETKSSEELGKTAGKDQLAGKLT 328
>dbj|BAA99946.1| (AP001309) geranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 357
Score = 166 bits (415), Expect = 5e-40
Identities = 97/240 (40%), Positives = 143/240 (59%), Gaps = 9/240 (3%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ V L +P +EP + EA R+ LAGGKR+RP + + A E VGG+ A+ A
Sbjct: 70 KAESVSAALNVSVPLQEPLTIQEAVRYSLLAGGKRVRPLLCIAACELVGGDEATAMSAAC 129
Query: 78 AIELIHNYSLVHDDIMDMDET--RRGKPTVHKVWGINMAILAGDLLFSKAFE---AISRA 132
A+E+IH SL+HDD+ MD+ RRGKPT HK +G +MA+LAGD L + AFE +S
Sbjct: 130 AVEMIHTSSLIHDDLPCMDDADLRRGKPTNHKEFGEDMAVLAGDALLALAFEHMTFVSNG 189
Query: 133 EISPEKKAKVLETIVKA--SNELCEGQALDL--EFENREMVSIEEYMRMISGKTGALFDA 188
++PE+ + + + KA + L GQ DL + N + V +E + KT AL +A
Sbjct: 190 LVAPERMIRAVMELAKAIGTKGLVAGQVTDLCSQGLNPDDVGLERLEFIHLHKTAALLEA 249
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+A +G I+G EE IE L ++ R +G+ FQ+ DD+LD+ ++LGK G D+ GK T
Sbjct: 250 AAVLGAIMGGGTEEEIEKLRKYARCIGLLFQVVDDILDVTESTKELGKTAGKDVMAGKLT 309
>dbj|BAB01936.1| (AP002033) geranylgeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 360
Score = 165 bits (413), Expect = 8e-40
Identities = 96/240 (40%), Positives = 143/240 (59%), Gaps = 9/240 (3%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ V L +P ++P + EA R+ LAGGKR+RP + + A E VGG+ A+ A
Sbjct: 73 KAESVSMALNVSVPPQDPLAIQEAVRYSLLAGGKRVRPLLCIAACELVGGDEATAMSAAC 132
Query: 78 AIELIHNYSLVHDDIMDMDET--RRGKPTVHKVWGINMAILAGDLLFSKAFE---AISRA 132
A+E+IH SL+HDD+ MD+ RRGKPT HKV+G +MA+LAGD L + AFE +S
Sbjct: 133 AVEMIHTSSLIHDDLPCMDDADLRRGKPTNHKVFGEHMAVLAGDALLALAFEHMTVVSSG 192
Query: 133 EISPEKKAKVLETIVKA--SNELCEGQALDL--EFENREMVSIEEYMRMISGKTGALFDA 188
++PE+ + + + KA + L GQ DL + N V +E + KT AL +A
Sbjct: 193 LVAPERMIRSVTELAKAIGTKGLVAGQVSDLCSQGLNPYDVGLERLEFIHLHKTAALLEA 252
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+A +G I+G EE I+ L ++GR +G+ FQ+ DD++D+ E+LGK G D+ K T
Sbjct: 253 AAVLGAIIGGGTEEEIQKLRKYGRCIGLLFQVVDDIIDVTESTEELGKTAGKDVMARKLT 312
>gb|AAD16018.1| (AF081514) geranylgeranyl diphosphate synthase [Taxus canadensis]
Length = 393
Score = 164 bits (411), Expect = 1e-39
Identities = 101/257 (39%), Positives = 146/257 (56%), Gaps = 7/257 (2%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIY 74
+K +A VD L + IP + P+ ++E+ R+ LAGGKR+RP + + A E VGG+ A+
Sbjct: 105 MKSKAVAVDAALDKAIPLEYPEKIHESMRYSLLAGGKRVRPALCIAACELVGGSQDLAMP 164
Query: 75 PAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRA 132
A A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G + A+LAGD L S AFE I+ A
Sbjct: 165 TACAMEMIHTMSLIHDDLPCMDNDDFRRGKPTNHKVFGEDTAVLAGDALLSFAFEHIAVA 224
Query: 133 ---EISPEKKAKVLETIVK--ASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFD 187
+ ++ +V+ + K S L GQ +D+ E V ++ + KT L +
Sbjct: 225 TSKTVPSDRTLRVISELGKTIGSQGLVGGQVVDITSEGDANVDLKTLEWIHIHKTAVLLE 284
Query: 188 ASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKK 247
S GGI+G E+ I + R+ R VG+ FQ+ DD+LD+ E+LGK G D+ K
Sbjct: 285 CSVVSGGILGGATEDEIARIRRYARCVGLLFQVVDDILDVTKSSEELGKTAGKDLLTDKA 344
Query: 248 TLIVAHFFENADEKAKE 264
T E A E A E
Sbjct: 345 TYPKLMGLEKAKEFAAE 361
>gb|AAG10424.1| (AF251012) GGDP synthase [Tagetes erecta]
Length = 361
Score = 164 bits (410), Expect = 2e-39
Identities = 97/254 (38%), Positives = 150/254 (58%), Gaps = 7/254 (2%)
Query: 17 ERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPA 76
E+A LV++ L +P K+P ++E+ R+ LAGGKR+RP + + A E VGG+ L A+ A
Sbjct: 77 EKANLVNQALDLAVPLKDPIKIHESMRYSLLAGGKRVRPVLCIAACELVGGDGLTAMPAA 136
Query: 77 VAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE- 133
A+E+IH SL+HDD+ MD D+ RRGKPT H V+G +A+L GD + S AFE ++ A
Sbjct: 137 CAVEMIHTMSLMHDDLPCMDNDDFRRGKPTNHMVYGEEIAVLGGDAMLSFAFEHMATATK 196
Query: 134 -ISPEKKAKVLETIVK--ASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASA 190
+S ++ + + + K S L GQ +D+ E + V +E + KT AL + S
Sbjct: 197 GVSSDRILRAIGELAKCIGSEGLVAGQVVDICSEGAD-VGLEHLEFIHLHKTAALLEGSV 255
Query: 191 KVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLI 250
+G I+G ++ IE L ++ R++G+ FQ+ DD+LD+ E+LGK G D+ K T
Sbjct: 256 VLGAILGGGSDGEIEKLRKFARSIGLLFQVVDDILDVTKSSEELGKTAGKDLVSDKTTYP 315
Query: 251 VAHFFENADEKAKE 264
E + E A+E
Sbjct: 316 KLLGIEKSREFAEE 329
>sp|P55785|HEP2_BACST HEPTAPRENYL DIPHOSPHATE SYNTHASE COMPONENT II (HEPPP SYNTHASE
SUBUNIT 2) >gi|1731683|dbj|BAA08725.1| (D49976)
component II of heptaprenyl diphosphate synthase
[Bacillus stearothermophilus]
Length = 320
Score = 163 bits (409), Expect = 2e-39
Identities = 118/341 (34%), Positives = 180/341 (52%), Gaps = 23/341 (6%)
Query: 7 KYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVG 66
K +++ + + V+E+L E + E L EAA H AGGKRIRP VL A
Sbjct: 2 KLKAMYSFLSDDLAAVEEEL-ERAVQSEYGPLGEAALHLLQAGGKRIRPVFVLLAARFGQ 60
Query: 67 GNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAF 126
+ + + AVA+ELIH SLVHDD++D + RRG+PT+ W A+ GD LF+++
Sbjct: 61 YDLERMKHVAVALELIHMASLVHDDVIDDADLRRGRPTIKAKWSNRFAMYTGDYLFARSL 120
Query: 127 EAISRAEISPEKKAKVL-ETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL 185
E + AE+ + +VL +TIV E+C G+ ++ + R + Y+R I KT L
Sbjct: 121 ERM--AELGNPRAHQVLAKTIV----EVCRGEIEQIKDKYRFDQPLRTYLRRIRRKTALL 174
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
AS ++G + E ++ L +G VGM+FQI DD+LD EE+LGKP GSD+ +G
Sbjct: 175 IAASCQLGALAAGAPEPIVKRLYWFGHYVGMSFQITDDILDFTGTEEQLGKPAGSDLLQG 234
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID 305
TL V + +DE+ K V E DV AE+ I +K +I+
Sbjct: 235 NVTLPV--LYALSDERVKAAIAAVGP------------ETDV-AEMAAVISAIKRTDAIE 279
Query: 306 YASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
+ ++ ++KA L+ LP + AR L LA ++ +R+Y
Sbjct: 280 RSYALSDRYLDKALHLLDGLPMNEARGLLRDLALYIGKRDY 320
>pir||S71230 geranylgeranyl pyrophosphate synthase (EC 2.5.1.-) 2 precursor -
Arabidopsis thaliana >gi|1229164|gb|AAB67730.1| (U44876)
pregeranygeranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 378
Score = 162 bits (406), Expect = 5e-39
Identities = 94/237 (39%), Positives = 141/237 (58%), Gaps = 6/237 (2%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A+ V++ L E IP EP ++EA R+ LA GKR+RP + L + E VGG I A
Sbjct: 94 KAESVNKALEEAIPVGEPLKIHEAMRYAILAAGKRVRPILCLASCELVGGQENATIPAAC 153
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEIS 135
A+E+IH SL+ DD+ MD D+ RRGKPT KV+G +AIL+G L S AFE ++ AEIS
Sbjct: 154 AVEMIHTMSLIKDDLPCMDNDDLRRGKPTTDKVYGEGVAILSGGALLSLAFEHMTTAEIS 213
Query: 136 PEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMISGKTGALFDASAK 191
E+ + + ++ + L GQA+D+ E ++ V +E + KT L + +A
Sbjct: 214 SERMVWAVRELARSIGTRGLVAGQAMDISSEGLDLNEVGLEHLEFIHVHKTAVLLETAAV 273
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G I+G ++E IE++ ++ R +G+ FQ+ DD+LD E+LGK G D GK T
Sbjct: 274 LGAIIGGGSDEEIESVRKFARCIGLLFQVVDDILDETKSSEELGKTAGKDQLAGKLT 330
>dbj|BAA86284.1| (AB034249) geranylgeranyl pyrophosphate synthase [Croton
sublyratus]
Length = 368
Score = 162 bits (406), Expect = 5e-39
Identities = 90/238 (37%), Positives = 143/238 (59%), Gaps = 6/238 (2%)
Query: 17 ERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPA 76
++A +++ L + +EP ++E+ R+ LAGGKR+RP + L A E VGG+ A+ A
Sbjct: 83 QKASAINQALEAAVSLREPLKIHESMRYSLLAGGKRVRPALCLAACELVGGDESMAMPAA 142
Query: 77 VAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE--AISRA 132
A+E+IH SL+HDD+ MD D+ RRGKPT H V+G N+A+LAGD L + AFE A+S
Sbjct: 143 CAVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHIVFGENVAVLAGDALLAFAFEHIAVSTL 202
Query: 133 EISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASA 190
+SP + + + + KA + L GQ +D+ E V +E+ + KT L + +
Sbjct: 203 NVSPVRIVRGVGELAKAIGAEGLVAGQVVDICSEGLSEVDLEKLEFIHIHKTAKLLEGAV 262
Query: 191 KVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G I+G +E +E L ++ R++G+ FQ+ DD+LD+ ++LGK G D+ K T
Sbjct: 263 VLGAIMGGGTDEEVEKLRKYARDIGLLFQVVDDILDVTKSSQELGKTAGKDLVADKVT 320
>pir||T09966 farnesyltranstransferase (EC 2.5.1.29) - Madagascar periwinkle
>gi|1063276|emb|CAA63486.1| (X92893) geranylgeranyl
pyrophosphate synthase [Catharanthus roseus]
Length = 357
Score = 162 bits (405), Expect = 7e-39
Identities = 94/237 (39%), Positives = 141/237 (58%), Gaps = 6/237 (2%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A V++ L + + +EP ++E+ R+ LAGGKR+RP + + A E GG A+ A
Sbjct: 73 KANSVNKALEDAVLVREPLKIHESMRYSLLAGGKRVRPMLCIAACELFGGTESVAMPSAC 132
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE-- 133
A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++A+LAGD L + AFE I+ A
Sbjct: 133 AVEMIHTMSLMHDDLPCMDNDDLRRGKPTNHKVFGEDVAVLAGDALLAFAFEHIATATKG 192
Query: 134 ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAK 191
+S E+ +V+ + K S L GQ +D+ E V +E + KT AL + S
Sbjct: 193 VSSERIVRVVGELAKCIGSEGLVAGQVVDVCSEGIADVGLEHLEFIHIHKTAALLEGSVV 252
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G IVG N+E I L ++ R +G+ FQ+ DD+LD+ ++LGK G D+ K T
Sbjct: 253 LGAIVGGANDEQISKLRKFARCIGLLFQVVDDILDVTKSSQELGKTAGKDLVADKVT 309
>gb|AAD12206.1| (AC006135) putative geranylgeranyl pyrophosphate synthase
[Arabidopsis thaliana]
Length = 347
Score = 162 bits (405), Expect = 7e-39
Identities = 95/238 (39%), Positives = 141/238 (58%), Gaps = 7/238 (2%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+A V+E L + +EP ++EA R+ LA GKR+RP + + A E VGG A+ A
Sbjct: 62 KANAVNEALDSAVSLREPIKIHEAIRYSLLARGKRVRPVLCIAACELVGGEESVALPAAC 121
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRA-EI 134
A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++A+LAGD L S AFE ++ + +
Sbjct: 122 AVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVFGEDVAVLAGDALISFAFEHLATSTAV 181
Query: 135 SPEKKAKVLETIVKA--SNELCEGQALDLEFENREM--VSIEEYMRMISGKTGALFDASA 190
SP + + + + KA S L GQ +DL + V +E + KT L +A+
Sbjct: 182 SPARVVRAIGELAKAIGSKGLVAGQVVDLTSGGMDQNDVGLEVLEFIHVHKTAVLLEAAT 241
Query: 191 KVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G IVG ++E +E L R+ R +G+ FQ+ DD+LD+ E+LGK G D+ K T
Sbjct: 242 VLGAIVGGGSDEEVEKLRRFARCIGLLFQVVDDILDVTKSSEELGKTAGKDLIADKLT 299
>gb|AAD47627.1| (AF153713) octylprenyl diphosphate synthase-like protein
[Pseudomonas sp. BG33R]
Length = 322
Score = 161 bits (404), Expect = 9e-39
Identities = 104/302 (34%), Positives = 159/302 (52%), Gaps = 24/302 (7%)
Query: 48 AGGKRIRPFVVLTATEAVG--GNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTV 105
AGGKR+RP +VL +A+G G+ L+ + A IE +H +L+HDD++DM RRG+ T
Sbjct: 42 AGGKRLRPLLVLLCGKALGREGDDLRLL--AATIEFLHTATLLHDDVVDMSGMRRGRETA 99
Query: 106 HKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFEN 165
+ +WG ++L GD ++S++FE + P V++ + +A+ + EG+ L L
Sbjct: 100 NAMWGNAPSVLVGDFMYSRSFEMMVELGSMP-----VMKILSQATRIIAEGEVLQLSKVR 154
Query: 166 REMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVL 225
+ E YM +I GKT F+AS + E EAL +G N+G+AFQ+ DD+L
Sbjct: 155 DASTTEETYMEVIRGKTAMFFEASTHSAAALCGATAEQAEALRTFGDNLGVAFQLVDDLL 214
Query: 226 DLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEE 285
D D E LGK VG D+ +GK TL + + + K KG IE+
Sbjct: 215 DYKGDAETLGKNVGDDLAEGKPTLPLIYTMREGTPEQAALVRKAI--------QKGGIED 266
Query: 286 DVKAEVMEAIELLKE-HGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVER 344
+EAI E GS++Y +++AR+ V +A + L LP S R L L+ F V R
Sbjct: 267 ------LEAIRAAVEASGSLEYTAQLARDYVARAIQCLEALPASEYRDALVELSEFAVAR 320
Query: 345 EY 346
+
Sbjct: 321 TH 322
>pir||A82688 octaprenyl-diphosphate synthase XF1391 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106399|gb|AAF84200.1|AE003970_7 (AE003970)
octaprenyl-diphosphate synthase [Xylella fastidiosa]
Length = 332
Score = 161 bits (404), Expect = 9e-39
Identities = 98/310 (31%), Positives = 160/310 (51%), Gaps = 18/310 (5%)
Query: 37 VLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMD 96
++ + A H +GGKR+RP + + A A+G A IE IH +L+HDD++D
Sbjct: 41 LINQIADHIICSGGKRLRPMLTMLAGHAIGPTGPHHHQLAAIIEFIHTATLLHDDVVDGS 100
Query: 97 ETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEG 156
E RR + T + +WG ++L GD L+S++F+ ++ +V++ + + +N + EG
Sbjct: 101 ELRRSRSTANALWGNAPSVLVGDFLYSRSFQLMTELA-----NLEVMQILAETTNRISEG 155
Query: 157 QALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGM 216
+ L L + Y+R+I KT LF A+A++G + + + + +G +G
Sbjct: 156 EVLQLLHVHNPDTDETTYLRVIERKTAILFAAAAQLGALASHADTQTQTRMYEYGMQLGY 215
Query: 217 AFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGD 276
AFQI DDVLD A+ +LGK +G D+ +GK TL V H ++D E+ + K GD
Sbjct: 216 AFQITDDVLDYTANNSQLGKNLGDDLAEGKATLPVIHAMTHSDAATCERLRMIISK--GD 273
Query: 277 VKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLEL 336
D EV+ AI + GS+DY+ + A A AL+ L E+ A L
Sbjct: 274 --------RDAMPEVLNAI---RTTGSLDYSRQRASAYAATAERALDGLLETEAVAALRG 322
Query: 337 LASFMVEREY 346
LA + ++R Y
Sbjct: 323 LARYAIQRTY 332
>dbj|BAA86285.1| (AB034250) geranylgeranyl pyrophosphate synthase [Scoparia dulcis]
Length = 351
Score = 160 bits (401), Expect = 2e-38
Identities = 92/238 (38%), Positives = 140/238 (58%), Gaps = 6/238 (2%)
Query: 17 ERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPA 76
E+A V++ L + KEP ++E+ R+ LAGGKR+RP + L A E VGG+ A+ A
Sbjct: 66 EKASSVNKALESAVSLKEPLKIHESMRYSLLAGGKRVRPMLCLAACELVGGHPSTAMPAA 125
Query: 77 VAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE- 133
+IE+IH SL+HDD+ MD D RRG PT H V+G ++A+LAGD L + +FE ++ A
Sbjct: 126 CSIEMIHTMSLMHDDLPCMDNDHLRRGHPTNHIVFGEDVAVLAGDALLAYSFEYLATATE 185
Query: 134 -ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASA 190
+ PE+ +V+ + K S L GQ +D+ E + +E + KT AL + S
Sbjct: 186 GVLPERIVRVIAELAKCIRSEGLLAGQVVDICSEGVSEIGLEHLEYIHLHKTAALLEGSV 245
Query: 191 KVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G I+G N+E +E L ++ R +G+ FQ+ DD+LD+ +LGK G D+ K T
Sbjct: 246 VLGAILGGGNDEEVERLRKFARCIGLLFQVVDDILDVTKTSVELGKTAGKDLVADKTT 303
>pir||E70549 probable heptaprenyl diphosphate syntetase - Mycobacterium
tuberculosis (strain H37RV) >gi|2114024|emb|CAB08957.1|
(Z95558) grcC1 [Mycobacterium tuberculosis]
Length = 335
Score = 159 bits (399), Expect = 3e-38
Identities = 104/323 (32%), Positives = 171/323 (52%), Gaps = 21/323 (6%)
Query: 24 EKLFELIPEKEPKVLYEAARHYPLAGGKRIRP-FVVLTATEAVGGNALKAIYPAVAIELI 82
E+L + + +V+ ++ H AGGKR RP F VL+A +A IE+I
Sbjct: 30 EQLMDTELRQADEVMSDSLLHLFNAGGKRFRPLFTVLSAQIGPQPDAAAVTVAGAVIEMI 89
Query: 83 HNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKV 142
H +L HDD+MD + RRG P+ + WG N+AILAGD L + A ++R + PE +
Sbjct: 90 HLATLYHDDVMDEAQVRRGAPSANAQWGNNVAILAGDYLLATASRLVAR--LGPEAVRII 147
Query: 143 LETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEE 202
+T +L GQ + + + SIE+Y++++ KTG+L A+ ++GG+ +E
Sbjct: 148 ADTFA----QLVTGQMRETRGTSENVDSIEQYLKVVQEKTGSLIGAAGRLGGMFSGATDE 203
Query: 203 YIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFF-ENADEK 261
+E LSR G VG AFQI DD++D+ ++ ++ GK G+D+R+G TL + + E+ +
Sbjct: 204 QVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPGTDVREGVHTLPMLYALRESGPDC 263
Query: 262 AKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEA 321
A+ + L G +++D AEV EA+ LL+ + A + + +A
Sbjct: 264 ARLRALL-----------NGPVDDD--AEVREALTLLRASPGMARAKDVLAQYAAQARHE 310
Query: 322 LNVLPESRARKDLELLASFMVER 344
L +LP+ R+ L L + V R
Sbjct: 311 LALLPDVPGRRALAALVDYTVSR 333
>sp|O66126|ISPA_MICLU GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP
SYNTHASE) >gi|2982677|dbj|BAA25265.1| (AB003187)
farnesyl diphosphate synthase [Micrococcus luteus]
Length = 291
Score = 159 bits (399), Expect = 3e-38
Identities = 96/254 (37%), Positives = 147/254 (57%), Gaps = 6/254 (2%)
Query: 21 LVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIE 80
L++E L + + L+EA + AGGKRIRP +VLT +++GGNA + +A+E
Sbjct: 15 LINESLLNKYHPAQSR-LHEAINYSLSAGGKRIRPLLVLTTLDSLGGNAHDGLPFGIALE 73
Query: 81 LIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEK 138
+IH YSL+HDD+ MD D+ RRGK T HK + AILAGD L + AF+ I +++ E
Sbjct: 74 MIHTYSLIHDDLPAMDNDDYRRGKLTNHKRFDEATAILAGDALLTDAFQCILNTQLNAEI 133
Query: 139 KAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIV 196
K ++ + A SN + GQ LD++ E++ + ++ E R+ KTG L A+ GI+
Sbjct: 134 KLSLINLLSTASGSNGMVYGQMLDMQGEHKTL-TLNELERIHIHKTGELIRAAIVSAGII 192
Query: 197 GTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFE 256
N+ IE L+ G+NVG+ FQI DD+LD+ E +GK VGSD+ K T + E
Sbjct: 193 MNFNDAQIEQLNIIGKNVGLMFQIKDDILDVEGSFENIGKTVGSDLNNDKSTYVSLLGLE 252
Query: 257 NADEKAKEKFLKVF 270
+ + +K + +
Sbjct: 253 ASKQLLNDKLTETY 266
>sp|Q08291|ISPA_BACST GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP
SYNTHASE) >gi|421467|pir||JX0257 geranyltranstransferase
(EC 2.5.1.10) - Bacillus stearothermophilus
>gi|391610|dbj|BAA02551.1| (D13293) farnesyl diphosphate
synthase [Bacillus stearothermophilus]
Length = 297
Score = 159 bits (397), Expect = 6e-38
Identities = 100/256 (39%), Positives = 142/256 (55%), Gaps = 11/256 (4%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPL-AGGKRIRPFVVLTATEAVGGNALKAI 73
+ E+ + V+ L I E + A Y L AGGKRIRP ++L+ A+G + +
Sbjct: 10 LNEQKQAVETALSRYIERLEGPAKLKKAMAYSLEAGGKRIRPLLLLSTVRALGKDPAVGL 69
Query: 74 YPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
A AIE+IH YSL+HDD+ MD D+ RRGKPT HKV+G MAILAGD L + AF+ I+
Sbjct: 70 PVACAIEMIHTYSLIHDDLPSMDNDDLRRGKPTNHKVFGEAMAILAGDGLLTYAFQLITE 129
Query: 132 AE---ISPEKKAKVLETIVKASNE--LCEGQALDLEFENREMVSIE-EYMRMISGKTGAL 185
+ I P + +++E + KA+ + GQA D+E E + + E EY+ KTG +
Sbjct: 130 IDDERIPPSVRLRLIERLAKAAGPEGMVAGQAADMEGEGKTLTLSELEYIHR--HKTGKM 187
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
S G ++G + L + ++G+AFQI DD+LD+ EEK+GKPVGSD
Sbjct: 188 LQYSVHAGALIGGADARQTRELDEFAAHLGLAFQIRDDILDIEGAEEKIGKPVGSDQSNN 247
Query: 246 KKTLIVAHFFENADEK 261
K T A EK
Sbjct: 248 KATYPALLSLAGAKEK 263
>gb|AAC77874.1| (AF020041) geranylgeranyl pyrophosphate synthase [Helianthus
annuus]
Length = 356
Score = 159 bits (397), Expect = 6e-38
Identities = 92/233 (39%), Positives = 138/233 (58%), Gaps = 6/233 (2%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIEL 81
V + L E I K P ++EA R+ LAGGKR+RP + + A E VGG A+ A A+E+
Sbjct: 75 VHKALDESIMIKNPPTIHEAMRYSLLAGGKRVRPILCIAACELVGGEEATAMPAACAVEM 134
Query: 82 IHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAI-SRAE-ISPE 137
IH SL+HDD+ MD D+ RRGKPT HKV+G ++A+LAGD L + AFE + SR E SP
Sbjct: 135 IHTMSLIHDDLPCMDNDDFRRGKPTNHKVYGEDVAVLAGDSLLAFAFEYVSSRTEGASPA 194
Query: 138 KKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGI 195
+ + + K+ + L GQ +D+ + + +++ + KT AL +AS +G I
Sbjct: 195 RVLAAIGELAKSIGTEGLVAGQVVDIASTGGQDIGLDQLEFIHIHKTAALLEASVVLGAI 254
Query: 196 VGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G ++ +E L + R +G+ FQ+ DD+LD+ E+LGK G D+ K T
Sbjct: 255 LGGGSDAQVEKLRTFARCIGLLFQVVDDILDVTKSSEELGKTAGKDLLVDKTT 307
>dbj|BAA22867.1| (AB001997) solanesyl diphosphate synthase [Rhodobacter capsulatus]
Length = 325
Score = 158 bits (396), Expect = 8e-38
Identities = 101/324 (31%), Positives = 170/324 (52%), Gaps = 21/324 (6%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALK-AIYPAVAIE 80
+D+ + E I K V+ ++H AGGKR+RP + L A A G LK A A IE
Sbjct: 20 MDQFINEGISSKVALVM-SVSKHVVEAGGKRMRPIMCLLAAYACGETNLKHAQKLAAIIE 78
Query: 81 LIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKA 140
++H +LVHDD++D RRG+PT + W A+L GD L ++AF+ + +
Sbjct: 79 MLHTATLVHDDVVDESGLRRGRPTANATWNNQTAVLVGDFLIARAFDLLVDLD-----NM 133
Query: 141 KVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTEN 200
+L+ + E+ EG+ L L+ +++ + + Y+++I GKT LF+ + + G +
Sbjct: 134 ILLKDFSTGTCEIAEGEVLQLQAQHQPDTTEDIYLQIIHGKTSRLFELATE-GAAILAGK 192
Query: 201 EEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADE 260
EY E L R+ + G AFQI DD+LD +D + LGK +G D+ +GK TL + +N
Sbjct: 193 PEYREPLRRFAGHFGNAFQIIDDILDYTSDADTLGKNIGDDLMEGKPTLPLIAAMQNTQG 252
Query: 261 KAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANE 320
+ ++ + I +++ + I +++ G++DY + A E E+A +
Sbjct: 253 EQRDLI-------------RRSIATGGTSQLEQVIAIVQNSGALDYCHKRATEETERALQ 299
Query: 321 ALNVLPESRARKDLELLASFMVER 344
AL +LPES R+ L L ++R
Sbjct: 300 ALEILPESTYRQALVNLTRLALDR 323
>dbj|BAA78047.1| (AB027706) GGPP synthase [Daucus carota]
Length = 367
Score = 157 bits (393), Expect = 2e-37
Identities = 95/256 (37%), Positives = 145/256 (56%), Gaps = 7/256 (2%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIY 74
+K K +++ L E +P ++P +++EA R+ LAGGKR+RP + + + E VGG A+
Sbjct: 80 MKTSGKKINKALDEAVPVQKPAIIHEAMRYSLLAGGKRVRPVLCIASCELVGGLESWAMP 139
Query: 75 PAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRA 132
A A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G AILAGD L S AFE ++ A
Sbjct: 140 MACALEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVYGEETAILAGDALLSLAFEHVADA 199
Query: 133 E--ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDA 188
++P + + + + A S L GQ +D+ + ++ V + + + KT L +A
Sbjct: 200 TDMVTPGRVVRAIAELGSAVGSQGLVAGQIMDICNQGKD-VDLNDLEYIHVHKTSKLLEA 258
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
S G I+G N +E L ++ R +G+ FQ+ DD+LD+ +LGK G D+ K T
Sbjct: 259 SVVCGAILGGGNVIEVERLRKYARCIGLLFQVVDDILDVTKSSAELGKTAGKDLVTDKTT 318
Query: 249 LIVAHFFENADEKAKE 264
E A A E
Sbjct: 319 YPKLMGLERAKRFATE 334
>pir||A81213 octaprenyl-diphosphate synthase (EC 2.5.1.-) NMA2161 [imported] -
Neisseria meningitidis (group B strain MD58, group A
strain Z2491) >gi|7225547|gb|AAF40771.1| (AE002389)
octaprenyl-diphosphate synthase [Neisseria meningitidis
MC58] >gi|7380782|emb|CAB85373.1| (AL162758)
octaprenyl-diphosphate synthase [Neisseria meningitidis
Z2491]
Length = 324
Score = 157 bits (393), Expect = 2e-37
Identities = 96/291 (32%), Positives = 160/291 (53%), Gaps = 18/291 (6%)
Query: 48 AGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHK 107
AGGKR+RP + + A +AVG + K A +E IH +L+HDD++D + RRG+ T +
Sbjct: 44 AGGKRLRPIMTILAGKAVGYDDEKLYSLAAMVEFIHTSTLLHDDVVDESDLRRGRATANN 103
Query: 108 VWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENRE 167
++G A+L GD L+++AF+ + + +VLE + A+N + EG+ + L
Sbjct: 104 LFGNAAAVLVGDFLYTRAFQLMVASG-----SMRVLEVMADATNIIAEGEVMQLMNIGNT 158
Query: 168 MVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDL 227
++ E+Y+++I KT LF+A+A+VG I+G + E+ AL +G VG AFQI DDVLD
Sbjct: 159 DITEEQYIQVIQYKTAKLFEAAAQVGAILGKASPEHERALKDYGMYVGTAFQIIDDVLDY 218
Query: 228 IADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDV 287
+ E+ GK VG D+ +GK TL + + E+ A DV + +E
Sbjct: 219 SGETEETGKNVGDDLAEGKPTLPLIYLMRQGSEQV-----------ANDV--RTALENAD 265
Query: 288 KAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLA 338
++ + + + ++ Y+ AR+ V+ A AL+ LP+S + + LA
Sbjct: 266 RSYFEKIHDYVVRSDALAYSIGEARKAVDCAVTALDALPDSEVKDAMIQLA 316
>gb|AAF08793.1|AF182828_1 (AF182828) geranyl diphosphate synthase large subunit [Mentha x
piperita] >gi|10637876|emb|CAC10561.1| (AJ249453) gpp
synthase large subunit [Mentha x piperita]
Length = 377
Score = 157 bits (392), Expect = 2e-37
Identities = 93/237 (39%), Positives = 138/237 (57%), Gaps = 6/237 (2%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAV 77
+AK V++ L + KEP ++E+ R+ LAGGKR+RP + + A E VGG+ A+ A
Sbjct: 93 KAKSVNKALEAAVQMKEPLKIHESMRYSLLAGGKRVRPMLCIAACELVGGDESTAMPAAC 152
Query: 78 AIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE-- 133
A+E+IH SL+HDD+ MD D+ RRGKPT H +G ++A+LAGD L S AFE ++ A
Sbjct: 153 AVEMIHTMSLMHDDLPCMDNDDLRRGKPTNHMAFGESVAVLAGDALLSFAFEHVAAATKG 212
Query: 134 ISPEKKAKVL-ETIVKASNE-LCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAK 191
PE+ +VL E V +E L GQ +D+ E V ++ + KT AL S
Sbjct: 213 APPERIVRVLGELAVSIGSEGLVAGQVVDVCSEGMAEVGLDHLEFIHHHKTAALLQGSVV 272
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+G I+G EE + L ++ +G+ FQ+ DD+LD+ ++LGK G D+ K T
Sbjct: 273 LGAILGGGKEEEVAKLRKFANCIGLLFQVVDDILDVTKSSKELGKTAGKDLVADKTT 329
>emb|CAC05969.1| (AL391763) polyprenyl synthetase [Streptomyces coelicolor]
Length = 386
Score = 157 bits (392), Expect = 2e-37
Identities = 113/307 (36%), Positives = 152/307 (48%), Gaps = 22/307 (7%)
Query: 46 PLAG--GKRIRPFVVLTATEAVGGNALKA--IYPAVAIELIHNYSLVHDDIMDMDETRRG 101
P AG GK IRP +VLTA A+GG +A + A A+EL+HN++L+HDD+MD D TRR
Sbjct: 92 PAAGNAGKAIRPALVLTAAAALGGPGARAAAVRAAAAVELVHNFTLLHDDVMDRDATRRH 151
Query: 102 KPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDL 161
+PT V+G AILAGD L + A + A+ P A + ELCEGQ D
Sbjct: 152 RPTAWTVFGDADAILAGDALQALALRLFA-ADPHPASAAAATR-LADCVMELCEGQHADT 209
Query: 162 EFENR--EMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQ 219
E R + V+++E + M KTGAL + VG + E +EAL +GR GMAFQ
Sbjct: 210 AMERRPPDEVTLDETLVMAEAKTGALLGCACAVGALYAGAATEDVEALDAFGREAGMAFQ 269
Query: 220 IWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKG 279
+ DDV+ + D GKP G+D+ KK+L V + A E G Y
Sbjct: 270 LIDDVIGIWGDPRHTGKPAGADLAARKKSLPVVAALTSGTPAAAELAELYTGPY------ 323
Query: 280 KGIIEEDVKAEVMEAIELLKEH-GSIDYASRIARELVEKA-NEALNVLPESRARKDLELL 337
D E +E L E G D+A A + + +A E +PE A L L
Sbjct: 324 ------DENKEDLERTALAVERAGGRDWAQAQAADRMARAMQELARAVPEPEAAGGLLAL 377
Query: 338 ASFMVER 344
A F+ R
Sbjct: 378 AEFVTRR 384
>pir||C83075 octaprenyl-diphosphate synthase PA4569 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950815|gb|AAG07957.1|AE004870_8 (AE004870)
octaprenyl-diphosphate synthase [Pseudomonas aeruginosa]
Length = 322
Score = 156 bits (391), Expect = 3e-37
Identities = 95/300 (31%), Positives = 153/300 (50%), Gaps = 20/300 (6%)
Query: 48 AGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHK 107
AGGKR+RP +VL A + +G A IE +H +L+HDD++D RRG+ T +
Sbjct: 42 AGGKRLRPLLVLLAGKTLGYKGDDLCLLAATIEFLHTSTLLHDDVVDASGLRRGRSTANA 101
Query: 108 VWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENRE 167
+WG ++L GD L++++FE + P V+ I +A+ + EG+ L L
Sbjct: 102 LWGNAPSVLVGDFLYARSFEMMVELGSMP-----VMRIISQATRVIAEGEVLQLSKVRDA 156
Query: 168 MVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDL 227
+ E YM +I GKT LF+AS + EE EAL R+G +G+AFQ+ DD+LD
Sbjct: 157 STTEETYMEVIRGKTAMLFEASTHSAAALCQAGEEQSEALRRFGDYLGIAFQLVDDLLDY 216
Query: 228 IADEEKLGKPVGSDIRKGKKTL-IVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEED 286
D LGK VG D+ +GK TL ++ + +E+A + I++
Sbjct: 217 RGDAATLGKNVGDDLAEGKPTLPLIVTMRDGTEEQA--------------ALVRKAIQQG 262
Query: 287 VKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
++ ++ G++DY + +AR+ +A L+ LP++ R L L+ F V R +
Sbjct: 263 GSQDLESVCAAVEAAGALDYTANLARDYAARAIACLDTLPDNEYRSALVELSEFAVARTH 322
>dbj|BAB05372.1| (AP001512) heptaprenyl diphosphate synthase component II (spore
germination protein C3) [Bacillus halodurans]
Length = 323
Score = 156 bits (390), Expect = 4e-37
Identities = 107/342 (31%), Positives = 175/342 (50%), Gaps = 22/342 (6%)
Query: 7 KYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATE--A 64
K +++ +E ++ +L E + + +L +A+ H AGGKRIRP VL A +
Sbjct: 2 KLADIYAHFQEDIFTIERELEEAVQARHD-ILRKASVHLLKAGGKRIRPVFVLLAGKFGT 60
Query: 65 VGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSK 124
N LK I AV +ELIH SLVHDD++D + RRGK T+ W +A+ GD +F+K
Sbjct: 61 YDVNVLKHI--AVPLELIHMASLVHDDVIDDADLRRGKKTIKSQWDNRIAMYTGDYMFAK 118
Query: 125 AFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGA 184
A + + + + + I A NE+C G+ + + + Y R I KT
Sbjct: 119 AVQTATYFD-----DPNIHQIISNAINEMCLGEVEQIRDQYNPNQHLRIYFRRIKRKTAL 173
Query: 185 LFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRK 244
L S ++G + + ++ L +G VGM+FQI DDVLD + EE+LGKP GSD+ +
Sbjct: 174 LIAVSCQLGALAAKADPAIVQKLYYFGYYVGMSFQITDDVLDFVGTEEQLGKPAGSDLLQ 233
Query: 245 GKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSI 304
G TL + + D AK ++ + D + E+V A ++ + G I
Sbjct: 234 GNVTLPALYALHH-DMHAK----RLIEQVLADRGNNSVHMEEVIAAIVSS-------GGI 281
Query: 305 DYASRIARELVEKANEALNVLPESRARKDLELLASFMVEREY 346
DYA I+ ++KA L+ LP+ ++ L+ +A+++ R++
Sbjct: 282 DYALSISDLYLKKAMRMLDHLPDDEPKQFLQEIANYIGRRKF 323
>pir||F70973 probable transferase - Mycobacterium tuberculosis (strain H37RV)
>gi|2661662|emb|CAA15768.1| (AL009198) idsB
[Mycobacterium tuberculosis]
Length = 350
Score = 155 bits (389), Expect = 5e-37
Identities = 100/299 (33%), Positives = 155/299 (51%), Gaps = 17/299 (5%)
Query: 48 AGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHK 107
+ GK R +V A A GG+ A + A+EL+HN++L+HDD+MD D TRRG+PTV
Sbjct: 67 SSGKYFRAALVYAAAAACGGDVGDATPVSAAVELVHNFTLLHDDVMDGDATRRGRPTVWS 126
Query: 108 VWGINMAILAGDLLFSKAFEAISRAEISPEKKA-KVLETIVKASNELCEGQALDLEFENR 166
VWG+ +AIL GD L + A ++ ++ E A + + + + +LC GQ D E +
Sbjct: 127 VWGVGVAILLGDALHATAVRILT--GLTDECVAVRAIRRLQMSCLDLCIGQFEDCLLEGQ 184
Query: 167 EMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLD 226
V++++Y+RM +GKT AL +G +V ++ I AL R+G +G+AFQ DD++
Sbjct: 185 PEVTVDDYLRMAAGKTAALTGCCCALGALVANADDATIAALERFGHELGLAFQCVDDLIG 244
Query: 227 LIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEED 286
+ D GKPVG+D+ + K TL V + E A E + Y
Sbjct: 245 IWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAATE----LAALYQAPA-------AM 293
Query: 287 VKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVERE 345
++V A L+K G A R A E ++ A+ LP++ DL L+ + RE
Sbjct: 294 TASDVERATALVKVAGGGHVAQRCADERIQ---AAIAALPDAVRSPDLIALSQLICRRE 349
>pir||A70377 octoprenyl-diphosphate synthase - Aquifex aeolicus
>gi|2983415|gb|AAC06998.1| (AE000712)
octoprenyl-diphosphate synthase [Aquifex aeolicus]
Length = 304
Score = 155 bits (389), Expect = 5e-37
Identities = 105/331 (31%), Positives = 177/331 (52%), Gaps = 31/331 (9%)
Query: 17 ERAKLVDEKLFELIPEKEPKV--LYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIY 74
E K ++++L E E PKV + E R+ +GGKR+RP L + GG+ KA+
Sbjct: 2 EILKAIEDRLVE---ELNPKVRLVLETGRYIVESGGKRLRPLFTLLVSGMCGGDPSKALP 58
Query: 75 PAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEI 134
VA+E IH SL+HDD++D +TRRG+ + + V+G +A+L GD +++K+
Sbjct: 59 LGVALEYIHVASLLHDDVVDRAKTRRGRESANLVFGNGVAVLTGDYMYAKSLHL-----F 113
Query: 135 SPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGG 194
S +++ + ++ EGQ L++ + +++S EEY ++I GKTG LF A VG
Sbjct: 114 STYGNMEMIRLVSGVVMDMAEGQVLEIS-KVGDIISEEEYFQIIDGKTGVLFGACFGVGA 172
Query: 195 IVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHF 254
+ G E ++ E L G +G AFQ+ DD LD D + LGKPVG+D+R+GK T +
Sbjct: 173 MSG-ECGDWRE-LYEAGLRLGRAFQLIDDALDYEGDPKVLGKPVGNDLREGKCTYPLISV 230
Query: 255 FENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIAREL 314
+N D + ++ L+ ED + + +EL G ++ A+E
Sbjct: 231 LDNLDREEVKRVLRGL--------------EDSEKLRKKVVEL----GGVEKTKERAKEE 272
Query: 315 VEKANEALNVLPESRARKDLELLASFMVERE 345
++ E ++ PE+ ++++ L F+VER+
Sbjct: 273 LKVVKEIISKYPENEYKREILKLIDFVVERK 303
>dbj|BAB01876.1| (AP000383) geranyl geranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 344
Score = 155 bits (388), Expect = 7e-37
Identities = 98/240 (40%), Positives = 142/240 (58%), Gaps = 9/240 (3%)
Query: 18 RAKLVDEKLFELIPEKEPKV-LYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPA 76
+AK V++ L E +P +EP++ + EA R+ L+ GKR+RP + L A E VGG A+ A
Sbjct: 57 KAKSVNKALEEAVPLREPELKIREAMRYTLLSDGKRVRPMLCLAACELVGGQESTAMSAA 116
Query: 77 VAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR--- 131
AIE++H SL+ DD+ MD D RRGKPT H V+G ++AILA L + A + +
Sbjct: 117 CAIEMLHASSLILDDLPCMDNDSLRRGKPTNHIVFGESIAILASQALIALAVQKTTSSTF 176
Query: 132 AEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIE--EYMRMIS-GKTGALFDA 188
A++ PE+ K ++ +VKA L GQ DL E S E++ I KT AL +A
Sbjct: 177 ADVPPERILKTVQEMVKAVEGLVAGQQADLAGEGMRFDSDTGLEHLEFIHIHKTAALLEA 236
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
+A +G I+G ++E IE L + R +G+ FQ+ DDVLD+ E+LGK G D+ GK T
Sbjct: 237 AAVMGAIMGGGSDEEIERLRSYARCIGLMFQVVDDVLDVTKSSEELGKTAGKDLIAGKLT 296
>pir||A82267 geranyltranstransferase VC0890 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655345|gb|AAF94052.1| (AE004173)
geranyltranstransferase [Vibrio cholerae]
Length = 294
Score = 155 bits (387), Expect = 9e-37
Identities = 95/233 (40%), Positives = 133/233 (56%), Gaps = 9/233 (3%)
Query: 38 LYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDM 95
L EA R+ L GGKR RP++V + +G PA A+E IH YSL+HDD+ MD
Sbjct: 30 LIEAMRYGLLLGGKRARPYLVYITGQMLGCELSDLDTPASAVECIHAYSLIHDDLPAMDD 89
Query: 96 DETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPE---KKAKVLETIVKASNE 152
DE RRGKPT H + AIL GD L + AF ++ ++S ++ +L+ + +AS
Sbjct: 90 DELRRGKPTCHIQFDEATAILTGDALQTLAFTILAEGDLSAAGETQRVAMLQALAEASGA 149
Query: 153 --LCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIV-GTENEEYIEALSR 209
+C GQALDL ENR ++S+EE + KTGAL + ++G + G + + L R
Sbjct: 150 QGMCLGQALDLAAENR-LISLEELETIHRNKTGALMRCAIRLGALAAGEKGRAMLPHLDR 208
Query: 210 WGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKA 262
+ VG+AFQ+ DD+LD+I+D E LGKP GSD K T E A +KA
Sbjct: 209 YAEAVGLAFQVQDDILDIISDTETLGKPQGSDQELNKSTYPALLGLEGAQQKA 261
>dbj|BAB07816.1| (AB037907) geranyl geranyl diphosphate synthase [Streptomyces
griseolosporeus]
Length = 348
Score = 155 bits (387), Expect = 9e-37
Identities = 85/215 (39%), Positives = 125/215 (57%), Gaps = 3/215 (1%)
Query: 50 GKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVW 109
GK IR + + A EA GG+ +A+ AVA+EL+HN+SL+HDD+MD D RRG+PTV
Sbjct: 65 GKMIRAALTVLAAEACGGDVQRAVCGAVAVELVHNFSLLHDDVMDGDLERRGRPTVWATL 124
Query: 110 GINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMV 169
G+ AILAGD+L ++ + E E + E + + L EGQ D+ FE+R +
Sbjct: 125 GVPAAILAGDVLLARGCAIL---EGDSEHRTWATELLTETIATLAEGQMADVAFEHRTTI 181
Query: 170 SIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIA 229
S+EE + + KT AL + ++G + E E L+++G ++GMAFQ+ DDVL +
Sbjct: 182 SLEEALAVSEAKTAALLSCACELGAGLSGGGAEARERLAKFGWHLGMAFQLVDDVLGIWG 241
Query: 230 DEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKE 264
D GKP GSD+R KK++ VA A+E
Sbjct: 242 DPAATGKPAGSDLRNRKKSIPVAAAMNGTGAAAEE 276
>emb|CAC08284.1| (AL392148) putative transferase [Streptomyces coelicolor]
Length = 336
Score = 154 bits (386), Expect = 1e-36
Identities = 103/325 (31%), Positives = 166/325 (50%), Gaps = 19/325 (5%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIEL 81
V+E L E + P + EAA+H AGGKR RP +V+ + + A + AV +EL
Sbjct: 27 VEEGLLEATKSEVPFIT-EAAQHLVRAGGKRFRPLLVMLSAQFGDPYAPGIVPSAVVVEL 85
Query: 82 IHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAK 141
H +L HDD+MD RRG P+ + W ++A+L GD LF++A + + A++ PE
Sbjct: 86 THLATLYHDDVMDEAAVRRGVPSANTRWDNSVAVLTGDFLFARASQIL--ADLGPE---- 139
Query: 142 VLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENE 201
+ A L GQ L+ ++ Y+ ++ GKTG+L S + G ++ +E
Sbjct: 140 AVRVQALAFERLVTGQILETAGPQDGRDPVDHYLDVLGGKTGSLVAVSCRFGAMMSGADE 199
Query: 202 EYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEK 261
++ L+++G +G+AFQ+ DDVLD+ +D ++ GK G+D+R+G TL V E A
Sbjct: 200 TVVDVLTQYGERLGVAFQLADDVLDIASDSDESGKTPGTDLREGIPTLPVLRLRERAARL 259
Query: 262 AKEKFLKVFGKYAGDVKGKGIIEEDVK--AEVMEAIELLKEHGSIDYASRIARELVEKAN 319
A D+ +++ D+ A EA+ LL+ H +++ A R E+A
Sbjct: 260 G----------LAEDLALCELLDSDLSDDARHAEALRLLRAHPALEQARRDTVRYAEEAR 309
Query: 320 EALNVLPESRARKDLELLASFMVER 344
AL L E A+ L L +V R
Sbjct: 310 AALAPLRECDAKAALVELCDAVVHR 334
>gb|AAD50025.1|AC007651_20 (AC007651) Very similar to prenyl transferase [Arabidopsis
thaliana]
Length = 379
Score = 154 bits (385), Expect = 1e-36
Identities = 111/347 (31%), Positives = 180/347 (50%), Gaps = 38/347 (10%)
Query: 9 DELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRP---FVVLTAT-EA 64
+ LF + + + +++ L ++ + P VL AA AGGKR+RP F+V AT E
Sbjct: 58 ETLFEVVADDLQRLNDNLLSIVGAENP-VLISAAEQIFSAGGKRMRPGLVFLVSRATAEL 116
Query: 65 VGGNALKAIYPAVA--IELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLF 122
G L + + IE+IH SL+HDD++D + RRG+ TVH+++G +A+LAGD +F
Sbjct: 117 AGLKELTVEHRRLGEIIEMIHTASLIHDDVLDESDMRRGRETVHELFGTRVAVLAGDFMF 176
Query: 123 SKAFEAISRAEISPEKKAKVLETIVK--ASNELCEGQAL-DLEFENREMVSIEEYMRMIS 179
++A + A + + K++ ++K AS E+ + +L D + V +++YM
Sbjct: 177 AQASWYL--ANLENLEVIKLISQVIKDFASGEIKQASSLFDCD------VKLDDYMLKSY 228
Query: 180 GKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVG 239
KT +L AS K I + E + ++G+N+G++FQ+ DD+LD E+LGKP
Sbjct: 229 YKTASLVAASTKGAAIFSKVESKVAEQMYQFGKNLGLSFQVVDDILDFTQSTEQLGKPAA 288
Query: 240 SDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDV--KAEVMEAIEL 297
+D+ KG T V EN + + + IIE + + EAIE+
Sbjct: 289 NDLAKGNITAPVIFALEN------------------EPRLREIIESEFCEPGSLEEAIEI 330
Query: 298 LKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVER 344
++ G I A +A+E E A + LN LP S R LE + F +ER
Sbjct: 331 VRNRGGIKKAQELAKEKAELALKNLNCLPRSGFRSALEDMVMFNLER 377
>dbj|BAA78046.1| (AB027705) GGPP synthase [Daucus carota]
Length = 366
Score = 154 bits (385), Expect = 1e-36
Identities = 92/266 (34%), Positives = 151/266 (56%), Gaps = 7/266 (2%)
Query: 17 ERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPA 76
E+A V++ L + +EP ++E+ R+ LAGGKR+RP + + A E GG+ A+ A
Sbjct: 80 EKAISVNKALDASVSLQEPVKIHESMRYSLLAGGKRVRPLLSIAACELFGGHEAVAMPSA 139
Query: 77 VAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE- 133
A+E+IH SL+HDD+ MD D+ RRGKPT HKV+G ++A+LAGD + + A + E
Sbjct: 140 CAVEMIHTMSLMHDDLPFMDNDDLRRGKPTNHKVYGESVAVLAGDAMLALAAFHLVATET 199
Query: 134 --ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDAS 189
+S ++ +V+ + KA + L GQ +D+ E + +E+ + KT AL + S
Sbjct: 200 RGVSSDQVVRVIVELAKAIGAEGLVAGQIVDVCSEGDPNLGLEDLEFIHRSKTAALLEGS 259
Query: 190 AKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTL 249
+G I+G N+E +E + ++ R +G+ FQ+ DD+LD+ ++LGK G D+ K T
Sbjct: 260 VVMGAILGGANDEEVEKVRKYARCIGLLFQVVDDILDVTKSSKELGKTAGKDLVADKTTY 319
Query: 250 IVAHFFENADEKAKEKFLKVFGKYAG 275
E + E + E + + AG
Sbjct: 320 PKLIGIEKSREFSDELKREAIDQLAG 345
>sp|P54383|ISPA_BACSU GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP
SYNTHASE) >gi|7447348|pir||A69961
geranyltranstransferase homolog yqiD - Bacillus subtilis
>gi|1303919|dbj|BAA12575.1| (D84432) YqiD [Bacillus
subtilis] >gi|2634862|emb|CAB14359.1| (Z99116) similar
to geranyltranstransferase [Bacillus subtilis]
Length = 272
Score = 152 bits (380), Expect = 6e-36
Identities = 96/261 (36%), Positives = 145/261 (54%), Gaps = 9/261 (3%)
Query: 9 DELFNRIKERAKLVDEKLFELIPEKE-PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG 67
++L + + +R K ++ +L + + P L ++ + AGGKR+RP +VL A G
Sbjct: 3 NKLTSFLADRKKTIENQLSVYTEKLDMPDSLKKSMLYSLQAGGKRLRPLIVLAVLNAYGK 62
Query: 68 NALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKA 125
+ I A+E+IH YSL+HDD+ MD D+ RRGKPT HKV+G A+LAGD L +++
Sbjct: 63 SEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTNHKVFGEATAVLAGDGLLTES 122
Query: 126 FEAISRA---EISPEKKAKVLETIVKASNE--LCEGQALDLEFENREMVSIEEYMRMISG 180
F+ I+ E+S EK+ +++ ++ A+ + GQ D+E NR+ V++EE +
Sbjct: 123 FKLITSHVSDEVSAEKRLRLVNELISAAGTEGMVGGQVADMEAGNRQ-VTLEELESIHER 181
Query: 181 KTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGS 240
KT L G I+ EE IE L + ++G+ FQI DD+LDL EEK+GK VGS
Sbjct: 182 KTSKLLGFCVIAGAILADAPEEDIETLRTFSSHIGIGFQIRDDILDLEGSEEKIGKRVGS 241
Query: 241 DIRKGKKTLIVAHFFENADEK 261
D K T E A K
Sbjct: 242 DTTNDKSTYPSLLSLEGAKHK 262
>emb|CAC11578.1| (AL445064) bifunctional short chain isoprenyl diphosphate synthase
related protein [Thermoplasma acidophilum]
Length = 322
Score = 152 bits (379), Expect = 8e-36
Identities = 109/336 (32%), Positives = 168/336 (49%), Gaps = 25/336 (7%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA 69
EL ++++E V+ +L E + +EP L AR+ AGGKR RP + + A E+
Sbjct: 6 ELHSKVEE----VNARLLETVKSEEPD-LDRMARYTIEAGGKRFRPLLTILAYESSTDEP 60
Query: 70 -LKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEA 128
K + A ELIH SL+HDDI+D RRG+PT+ G+N AI+ D LF+KA+E
Sbjct: 61 YFKILDLATGYELIHTASLIHDDIIDNSPMRRGRPTLSYKEGVNNAIVVADYLFAKAYEL 120
Query: 129 ISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDA 188
SR V + + AS+ L EGQ L+ +S + Y R+I KT F+A
Sbjct: 121 GSRYG------PIVSKVMADASSRLAEGQILEAVNLGNLNISEDTYYRIIENKTAHFFEA 174
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
A+ I + LS + N+GMAFQ+ DD+LD+ D++ GKP DI+ T
Sbjct: 175 CARGATIAANADLNTRNMLSGFAFNLGMAFQVTDDILDITGDDKYTGKPTFVDIKHDALT 234
Query: 249 LIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYAS 308
L + + N+DE ++K + G + G I++D+ + G+IDY+
Sbjct: 235 LPIIYALHNSDENDRDKIV-------GMINGSIEIDKDLLKRI------FLRSGAIDYSF 281
Query: 309 RIARELVEKANEALNVLPESRARKDLELLASFMVER 344
IA+ + A + L + S L LA +++R
Sbjct: 282 GIAKRFITSAMDYLKNVTRSPDIDLLMELALMVIDR 317
>dbj|BAB06500.1| (AP001516) geranyltranstransferase [Bacillus halodurans]
Length = 294
Score = 151 bits (377), Expect = 1e-35
Identities = 97/258 (37%), Positives = 147/258 (56%), Gaps = 12/258 (4%)
Query: 9 DELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGN 68
DE+ + I+ER E+L P +L + + AGGKRIRP ++L ++ +
Sbjct: 10 DEIKDIIEERMPAHIERL------NSPDMLKNSMLYSLKAGGKRIRPALLLATMKSFQKD 63
Query: 69 ALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAF 126
+ I A AIE+IH YSL+HDD+ MD D+ RRGKPT HKV+G AILAGD L + +F
Sbjct: 64 ISQGIDLACAIEMIHTYSLIHDDLPSMDDDDIRRGKPTNHKVFGEAHAILAGDALLTYSF 123
Query: 127 EAISRAE-ISPEKKAKVLETIVKASNE--LCEGQALDLEFENREMVSIEEYMRMISGKTG 183
E +++ + + P K ++E + +A+ + GQ D+E EN+++ ++E + KTG
Sbjct: 124 EIVAKMKGVDPAKTLCLIEELARAAGPEGMVGGQVADIEGENQKL-TVEGLEYIHHHKTG 182
Query: 184 ALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIR 243
AL + G + +E+ IE + R+ R +G+ FQI DD+LD+ D+ +GKPVGSD
Sbjct: 183 ALLSFAIVAGARLADASEQDIENIRRFSRELGLLFQIKDDILDVEGDQAAIGKPVGSDDG 242
Query: 244 KGKKTLIVAHFFENADEK 261
K T E A EK
Sbjct: 243 NQKSTYPSLLTLEGAKEK 260
>dbj|BAA82614.1| (AB016094) farnesyl diphosphate synthase (SelFPS) [Synechococcus
elongatus]
Length = 300
Score = 150 bits (374), Expect = 3e-35
Identities = 101/258 (39%), Positives = 143/258 (55%), Gaps = 10/258 (3%)
Query: 16 KERAKLVDEKLFELIPEKE--PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAI 73
+ R LV+E L L+P E P+ L++A R+ L GGKR+RP + A E G +
Sbjct: 13 RSRQALVEEALNRLLPPAEVAPQRLHQAMRYAVLGGGKRVRPLLCYAAGEVSGAELERLS 72
Query: 74 YPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAIS- 130
A A+ELIH YSLVHDD+ MD D RRGKPT H + A+LAGD L S AF+ ++
Sbjct: 73 TAAAALELIHVYSLVHDDLPCMDDDVLRRGKPTCHVEYDEATALLAGDSLQSLAFQLLAE 132
Query: 131 -RAEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFD 187
R SP+ + ++LE + +A S + GQA+DLE + + ++ E M KTGAL
Sbjct: 133 YRVADSPQTQLRMLEHLARAAGSRGMAGGQAIDLEATGKTL-TLPELEFMHIHKTGALIR 191
Query: 188 ASAKVGGIVGTE-NEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGK 246
AS +G G + ++ L + + +G+AFQ+ DDVLD + LGK G D R+GK
Sbjct: 192 ASVILGANCGRALASKDMDRLDHFAKRIGLAFQVVDDVLDAQSTTATLGKTAGKDARQGK 251
Query: 247 KTLIVAHFFENADEKAKE 264
T + E A A+E
Sbjct: 252 PTYVSTVGVEAARAMAQE 269
>gb|AAF12843.1|AF203881_16 (AF203881) geranyltransferase [Zymomonas mobilis]
Length = 298
Score = 149 bits (373), Expect = 4e-35
Identities = 93/258 (36%), Positives = 140/258 (54%), Gaps = 13/258 (5%)
Query: 30 IPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVH 89
+PE + L EA R+ + GGKR+RP +V+ + A+ +AIE IH YSL+H
Sbjct: 26 VPEDPRRRLVEAMRYAAIGGGKRLRPLLVVATCALFNVDREAALRVGMAIECIHVYSLIH 85
Query: 90 DDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEI--SPEKKAKVLET 145
DD+ MD D+ RRGKPTVHK + A+L+GD L + AFE +S +I P + ++++
Sbjct: 86 DDMPCMDNDDLRRGKPTVHKAFDDASAVLSGDALQALAFEILSEEKIHTDPHVRLELIQA 145
Query: 146 IVK--ASNELCEGQALDLEFENREM-VSIEEYMRMISGKTGALFDASAKVGGIVGTENEE 202
++ + + GQA+DL E + + R+ KTGALF + G I+G +N++
Sbjct: 146 LLSPPVKDGMVGGQAIDLAAETSTVPFDLPTITRLQQLKTGALFGFCLEAGAIMGRQNKD 205
Query: 203 YIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKA 262
+ L + R++G+AFQI DD++D DE GK VG D GK T + E A +A
Sbjct: 206 IRDRLKAYARDIGLAFQIADDLIDAEGDEAVAGKAVGKDAAAGKATFLSLLGLEKARSQA 265
Query: 263 KE------KFLKVFGKYA 274
+ L VFG A
Sbjct: 266 QALVDQAIAHLSVFGSEA 283
>sp|P45204|ISPA_HAEIN GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP
SYNTHASE) >gi|1074074|pir||C64123
geranyltranstransferase (EC 2.5.1.10) - Haemophilus
influenzae (strain Rd KW20) >gi|1574277|gb|AAC23087.1|
(U32822) geranyltranstransferase (ispA) [Haemophilus
influenzae Rd]
Length = 295
Score = 149 bits (372), Expect = 5e-35
Identities = 96/269 (35%), Positives = 150/269 (55%), Gaps = 9/269 (3%)
Query: 5 VGKYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEA 64
+G + E +++ R E FE I E L EA ++ L GGKR+RPF+V +
Sbjct: 1 MGHFSEELQQVQTRINRFLEAQFEGI-ESHNAPLLEAMKYALLLGGKRVRPFLVYATGQM 59
Query: 65 VGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLF 122
+G Y A AIE IH YSL+HDD+ MD D RRG PT H + AILAGD L
Sbjct: 60 LGAEKQTLDYAAAAIEAIHAYSLIHDDLPAMDDDNLRRGHPTCHIQFDEATAILAGDALQ 119
Query: 123 SKAFEAISRA-EISPEKKAKVLETIVKAS--NELCEGQALDLEFENREMVSIEEYMRMIS 179
S AFE +++ IS E+K +++ + + + +C GQ+LDL E+++ +S+ E +
Sbjct: 120 SFAFEILTKTPNISTEQKLALIQILAQGAGVQGMCLGQSLDLISEHKQ-ISLSELELIHR 178
Query: 180 GKTGALFDASAKVGGIVGTE--NEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKP 237
KTGAL A+ K+G I ++ ++L+++ +G+AFQ+ DD+LD+ D ++GK
Sbjct: 179 NKTGALLIAALKLGFICSPHFTDKRLEQSLTQYAEAIGLAFQVQDDILDIEGDSAEIGKQ 238
Query: 238 VGSDIRKGKKTLIVAHFFENADEKAKEKF 266
VG+D+ K T A +KA++ +
Sbjct: 239 VGADLDLDKSTYPKLLGLSGAKQKAQDLY 267
>sp|O66952|ISPA_AQUAE GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP
SYNTHASE) >gi|7447352|pir||E70365 geranylgeranyl
pyrophosphate synthase - Aquifex aeolicus
>gi|2983323|gb|AAC06913.1| (AE000705) geranylgeranyl
pyrophosphate synthase [Aquifex aeolicus]
Length = 262
Score = 149 bits (372), Expect = 5e-35
Identities = 97/256 (37%), Positives = 146/256 (56%), Gaps = 18/256 (7%)
Query: 14 RIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAI 73
RI+ + ++++L E++ + P+ L EA ++YPL GKRIRP + A+GGN AI
Sbjct: 3 RIETWKEKIEKRLNEILKPEGPEELIEAMKYYPLQKGKRIRPLFTVAVASALGGNEDDAI 62
Query: 74 YPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
IELIHNYSL+HDD+ MD D RRG PT H +G MA+LAGD L + FE +S+
Sbjct: 63 TVGSGIELIHNYSLIHDDLPCMDNDVWRRGLPTCHIKFGEAMALLAGDALLTYTFEVLSQ 122
Query: 132 AE----ISPEKKAKVLETIVK--ASNELCEGQALDLE-FENREMVSIEEYMRMISGKTGA 184
E +S E+ ++ + I + SN + GQ LD++ +E+ VS++ KTGA
Sbjct: 123 RENYKTLSCEEILEINKIIAQKAGSNGMVGGQVLDIKGYEDLYEVSVK--------KTGA 174
Query: 185 LFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRK 244
LF+A G +V E+ ++ + GR VG+ FQ+ DD LD EKLG+ + +I+K
Sbjct: 175 LFEACFMCGAVVAKRREK-LKEMESIGRKVGLLFQMVDDYLDKDGFYEKLGECLKEEIKK 233
Query: 245 GKKTLIVAHFFENADE 260
+ L F+ + E
Sbjct: 234 LYEELKEKEIFKESQE 249
>gb|AAD38295.1|AC007789_21 (AC007789) putative geranylgeranyl pyrophosphate synthase [Oryza
sativa] >gi|11320851|dbj|BAB18334.1| (AP002865) putative
geranylgeranyl pyrophosphate synthase [Oryza sativa]
Length = 376
Score = 149 bits (372), Expect = 5e-35
Identities = 97/256 (37%), Positives = 144/256 (55%), Gaps = 14/256 (5%)
Query: 3 MGVGKYDELFNR-IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTA 61
+G G +D F R + RA V + L +P P+ L E+ R+ LAGGKR+RP + L A
Sbjct: 77 VGGGSFD--FQRYLSARADAVHDALDRAMPRGFPERLCESMRYSVLAGGKRVRPVLALAA 134
Query: 62 TEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGD 119
E VGG+A A A A+E+IH SL+HDD+ MD D RRG+P+ H +G A+LAGD
Sbjct: 135 CELVGGDAAAATPVACAVEMIHTMSLIHDDMPCMDDDALRRGRPSNHVAFGEFTALLAGD 194
Query: 120 LLFSKAFEAISRA----EISPEKKAKVLETIVKASNE--LCEGQALDLEFENREM-VSIE 172
L + AFE ++R + ++ + + + AS + GQ D E E + +++
Sbjct: 195 ALHALAFEHVARGCGDHGVPADRTLRAVAELGSASGTGGVAAGQVADKESEGLPVSLAML 254
Query: 173 EYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEE 232
EY+ + KT L +A+A G IVG + +E + R+ R VG+ FQ+ DDVLD+ + E
Sbjct: 255 EYIHV--HKTARLLEAAAVSGAIVGGGADAEVERVRRYARCVGLLFQVVDDVLDMTSTSE 312
Query: 233 KLGKPVGSDIRKGKKT 248
+LGK G D+ K T
Sbjct: 313 QLGKTAGKDVEADKAT 328
>gb|AAD30584.1|AC007260_15 (AC007260) lcl|prt_seq No definition line found [Arabidopsis
thaliana]
Length = 390
Score = 148 bits (370), Expect = 9e-35
Identities = 112/347 (32%), Positives = 175/347 (50%), Gaps = 42/347 (12%)
Query: 11 LFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRP---FVVLTATEAVGG 67
LF + + +++ L ++ + P VL AA AGGKR+RP F+V AT + G
Sbjct: 71 LFELVAVDLQTLNDNLLSIVGAENP-VLISAAEQIFGAGGKRMRPGLVFLVSHATAELAG 129
Query: 68 NALKAIYP-----AVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLF 122
LK + A IE+IH SL+HDD++D + RRGK TVH+++G +A+LAGD +F
Sbjct: 130 --LKELTTEHRRLAEIIEMIHTASLIHDDVLDESDMRRGKETVHELFGTRVAVLAGDFMF 187
Query: 123 SKAFEAISRAEISPEKKAKVLETIVK--ASNELCEGQAL-DLEFENREMVSIEEYMRMIS 179
++A + A + + K++ ++K AS E+ + +L D + ++EY+
Sbjct: 188 AQASWYL--ANLENLEVIKLISQVIKDFASGEIKQASSLFDCD------TKLDEYLLKSF 239
Query: 180 GKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVG 239
KT +L AS K I + E + +G+N+G++FQI DD+LD E+LGKP G
Sbjct: 240 YKTASLVAASTKGAAIFSRVEPDVTEQMYEFGKNLGLSFQIVDDILDFTQSTEQLGKPAG 299
Query: 240 SDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDV--KAEVMEAIEL 297
SD+ KG T V E + + + IIE + + EAIE
Sbjct: 300 SDLAKGNLTAPVIFALER------------------EPRLREIIESEFCEAGSLEEAIEA 341
Query: 298 LKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVER 344
+ + G I A +ARE + A + L LP S R LE + + +ER
Sbjct: 342 VTKGGGIKRAQELAREKADDAIKNLQCLPRSGFRSALEDMVLYNLER 388
>pir||B75457 polyprenyl synthase - Deinococcus radiodurans (strain R1)
>gi|6458656|gb|AAF10509.1|AE001946_1 (AE001946)
polyprenyl synthase [Deinococcus radiodurans]
Length = 320
Score = 146 bits (366), Expect = 3e-34
Identities = 96/308 (31%), Positives = 159/308 (51%), Gaps = 27/308 (8%)
Query: 48 AGGKRIRPFVVLTATEAVGG--NALKAIYP-------AVAIELIHNYSLVHDDIMDMDET 98
AGGKR+RP V L A +A+G +AL + +V +EL+H+ SL+HDD++D +
Sbjct: 31 AGGKRVRPLVTLLAAQALGAGPDALATSHSWDELLRLSVCVELLHSASLLHDDLIDDSDK 90
Query: 99 RRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQA 158
RRG+ T + +G +++++GD + ++ +S SP + +A++ +CEG+
Sbjct: 91 RRGQETAFRRFGNVVSVMSGDFMLARLLGELSGMPGSPA----LTRAFGQAASVICEGEV 146
Query: 159 LDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAF 218
L + + S E Y ++I GKT AL + +A+ ++ ++ +ALS +GR GMAF
Sbjct: 147 LQFQVASYADYSFENYFQVIHGKTAALLELAAQAPAMLLGADDSARDALSTFGREYGMAF 206
Query: 219 QIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVK 278
Q+ DD+LDL+ +E ++GKPVG D+R+GK T V + L+ + AG+
Sbjct: 207 QMQDDLLDLLGEEAQIGKPVGGDLREGKATYPVLCLLGGPHDAEVRAILE---RRAGE-- 261
Query: 279 GKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLA 338
+V I L ++ + D R A AL+ LP S AR L LA
Sbjct: 262 ---------DGDVARMIALARQERTDDCTREEIRRRARLAIAALDALPPSPARTALAALA 312
Query: 339 SFMVEREY 346
+ R +
Sbjct: 313 ERELNRTH 320
>gi|11465734 prenyl transferase [Porphyra purpurea]
>gi|1709766|sp|P51268|PREA_PORPU PRENYL TRANSFERASE
>gi|2147960|pir||S73189 prenyl transferase A - red alga
(Porphyra purpurea) chloroplast
>gi|1276734|gb|AAC08154.1| (U38804) prenyl transferase
[Porphyra purpurea]
Length = 323
Score = 146 bits (365), Expect = 3e-34
Identities = 105/339 (30%), Positives = 168/339 (48%), Gaps = 29/339 (8%)
Query: 11 LFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNAL 70
LF+ I++ V+ L + + P +LY AA+H AGGKR+RP +VL ++
Sbjct: 7 LFHPIEKELYSVEHNLKSVAGTRHP-ILYAAAKHLFEAGGKRLRPAIVLLVAKSTSEQ-- 63
Query: 71 KAIYP-----AVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKA 125
+ I P A E+IH SLVHDD++D TRRG+ TVHK++ +A+LAGD LF+++
Sbjct: 64 QEIKPGQRRLAEITEIIHTASLVHDDVIDECSTRRGEKTVHKLFNTKIAVLAGDFLFAQS 123
Query: 126 FEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL 185
++ +V++ I K + EG+ +SI++Y+ KT +L
Sbjct: 124 SWYLANIG-----NLEVVKVITKVITDFAEGEIRQGLVHFDPSISIDDYIEKSFYKTASL 178
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
AS + ++ N + L +G+++G+AFQI DDVLD+ + LGKP G+D G
Sbjct: 179 VAASCRGAAMLNDLNSQMHNDLYLYGKHMGLAFQIMDDVLDIAGSTKSLGKPSGADFMNG 238
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID 305
T + F + K + + F E D+ A+ L+K+ G I
Sbjct: 239 NLTAPIL-FALTQEGKLDQLIQREFSD-----------ERDISL----ALFLIKKSGGIT 282
Query: 306 YASRIARELVEKANEALNVLPESRARKDLELLASFMVER 344
A +A+E V+ A L LP+S L+ L F++ R
Sbjct: 283 KAKDLAKEQVQAALCCLQFLPKSAPVSSLKELTHFIITR 321
>sp|P22939|ISPA_ECOLI GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP
SYNTHASE) >gi|78395|pir||JQ0665 geranyltranstransferase
(EC 2.5.1.10) - Escherichia coli
>gi|216584|dbj|BAA00599.1| (D00694) ORF2 for farnesyl
diphosphate synthase [Escherichia coli]
>gi|1773105|gb|AAB40177.1| (U82664) geranyltransperase
[Escherichia coli] >gi|1786623|gb|AAC73524.1| (AE000148)
geranyltranstransferase (farnesyldiphosphate synthase)
[Escherichia coli K12]
Length = 299
Score = 146 bits (364), Expect = 4e-34
Identities = 88/233 (37%), Positives = 131/233 (55%), Gaps = 9/233 (3%)
Query: 40 EAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDE 97
E ++ L GGKR+RPF+V G + PA A+E IH YSL+HDD+ MD D+
Sbjct: 34 ETMQYGALLGGKRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDD 93
Query: 98 TRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRA---EISPEKKAKVLETIVKASN--E 152
RRG PT H +G AILAGD L + AF +S A E+S + ++ + AS
Sbjct: 94 LRRGLPTCHVKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAG 153
Query: 153 LCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGI-VGTENEEYIEALSRWG 211
+C GQALDL+ E + V ++ R+ KTGAL A+ ++G + G + + L ++
Sbjct: 154 MCGGQALDLDAEGKH-VPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYA 212
Query: 212 RNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKE 264
++G+AFQ+ DD+LD++ D LGK G+D + GK T E A +KA++
Sbjct: 213 ESIGLAFQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARD 265
>pir||A82322 octaprenyl-diphosphate synthase VC0434 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9654858|gb|AAF93607.1|
(AE004131) octaprenyl-diphosphate synthase [Vibrio
cholerae]
Length = 348
Score = 145 bits (363), Expect = 6e-34
Identities = 86/296 (29%), Positives = 153/296 (51%), Gaps = 17/296 (5%)
Query: 49 GGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKV 108
GGKR+RP + + + +A+G A IE IH +L+HDD++D + RRGK T +
Sbjct: 68 GGKRLRPLLAVLSAKALGYQGSHHTTAAAFIEFIHTATLLHDDVVDESDLRRGKATANAA 127
Query: 109 WGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREM 168
+G ++L GD +++++F+ ++ K+L+ + A N + EG+ L N
Sbjct: 128 FGNAASVLVGDFIYTRSFQMMTELG-----SMKILKLMSDAVNVIAEGEVQQLMNCNDPD 182
Query: 169 VSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLI 228
+ YM++I KT LF+A+ ++G I+ + E A+ +G+ +G AFQ+ DDV+D
Sbjct: 183 TTEASYMQVIYSKTARLFEAATQIGAILCDASPEVELAMQNYGKYLGTAFQLIDDVMDYT 242
Query: 229 ADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVK 288
+D +++GK VG D+ +GK TL + + ++ + + + K G
Sbjct: 243 SDGDEMGKNVGDDLAEGKPTLPLLYAMQHGNPEQAAMIREAIEKANG------------M 290
Query: 289 AEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDLELLASFMVER 344
+ + E + +++ GS+ Y A +KA L +LPES ++ L LA V R
Sbjct: 291 SRLNEILAAMEQTGSLQYTIEKALHEADKAIAELAILPESEYKQALITLAHMAVNR 346
>gb|AAD43148.1|AC007504_3 (AC007504) geranyl geranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 336
Score = 145 bits (362), Expect = 7e-34
Identities = 100/273 (36%), Positives = 149/273 (53%), Gaps = 19/273 (6%)
Query: 10 ELFNRIKERAKLVDEKLFE-------LIPEKEPKV-LYEAARHYPLAGGKRIRPFVVLTA 61
E + +K +AK +++ L +P EP + +++A R+ L GGKR+RP + L A
Sbjct: 31 EFISYMKNKAKSINKALDNSIPLCNNFVPLWEPVLEVHKAMRYTLLPGGKRVRPMLCLVA 90
Query: 62 TEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGD 119
E VGG A+ A A+E+IH SL+ DD+ MD D RRGKPT HKV+G +ILA +
Sbjct: 91 CELVGGQESTAMPAACAVEMIHAASLILDDLPCMDDDSLRRGKPTNHKVFGEKTSILASN 150
Query: 120 LLFSKAFE---AISRAEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEY 174
L S A + A + ++ E+ + ++ + +A + L GQA DL E + ++
Sbjct: 151 ALRSLAVKQTLASTSLGVTSERVLRAVQEMARAVGTEGLVAGQAADLAGERMSFKNEDDE 210
Query: 175 MRMIS----GKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIAD 230
+R + KT L +A+A VG I+G ++E IE L + R VG+ FQ+ DDVLD
Sbjct: 211 LRYLELMHVHKTAVLVEAAAVVGAIMGGGSDEEIERLKSYARCVGLMFQVMDDVLDETKS 270
Query: 231 EEKLGKPVGSDIRKGKKTLIVAHFFENADEKAK 263
E+LGK G D+ GK T +NA E AK
Sbjct: 271 SEELGKTAGKDLITGKLTYPKVMGVDNAREYAK 303
>pir||F83139 geranyltranstransferase PA4043 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950239|gb|AAG07430.1|AE004821_3
(AE004821) geranyltranstransferase [Pseudomonas
aeruginosa]
Length = 295
Score = 144 bits (360), Expect = 1e-33
Identities = 94/245 (38%), Positives = 136/245 (55%), Gaps = 14/245 (5%)
Query: 14 RIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAI 73
R + R + LF + P +E + LYEA R+ + GGKR+RP + A EA+GG +A
Sbjct: 8 RCQARVDAALDALF-VAPREELQRLYEAMRYSVMNGGKRVRPLLAYAACEALGGAPQRAD 66
Query: 74 YPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
A A+ELIH YSLVHDD+ MD D+ RRG+PT H+ + AILA D L + AFE ++
Sbjct: 67 AAACAVELIHAYSLVHDDLPAMDDDDLRRGQPTTHRAFDEATAILAADGLQALAFEVLAD 126
Query: 132 AEISPEKKAKVLETIVK-----ASNELCEGQALDLEFEN--REMVSIEEYMRMISGKTGA 184
+P++ A LE + + S + GQA+DL + ++E R KTGA
Sbjct: 127 TRRNPQEHAVCLEMLTRLARAAGSAGMVGGQAIDLGSVGVALDQAALEVMHR---HKTGA 183
Query: 185 LFDASAKVGGIV-GTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIR 243
L +AS ++G + G + AL R+ +G+AFQ+ DD+LD+ +D LGK G D
Sbjct: 184 LIEASVRLGALASGRAEPASLAALERYAEAIGLAFQVQDDILDVESDTATLGKTQGKDQA 243
Query: 244 KGKKT 248
K T
Sbjct: 244 HNKPT 248
>gi|11467329 prenyl transferase [Cyanophora paradoxa]
>gi|399307|sp|P31171|PREA_CYAPA PRENYL TRANSFERASE
>gi|99282|pir||A40433 prephytoene pyrophosphatase
dehydrogenase (crtE) homolog - Cyanophora paradoxa
>gi|7447564|pir||T06874 probable prenyl transferase (EC
2.5.1.-) - Cyanophora paradoxa cyanelle
>gi|336639|gb|AAA65472.1| (M37111) prephytoene
pyrophosphate dehydrogenase [Cyanophora paradoxa]
>gi|1016130|gb|AAA81217.1| (U30821) prenyl transferase
[Cyanophora paradoxa]
Length = 323
Score = 143 bits (358), Expect = 2e-33
Identities = 100/335 (29%), Positives = 171/335 (50%), Gaps = 25/335 (7%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNAL---K 71
++ L+ + L +L+ P +L A+ H A GKR RP +VL ++A N + +
Sbjct: 11 VENELDLLTKNLKKLVGSGHP-ILSAASEHLFSASGKRPRPAIVLLISKATMENEIITSR 69
Query: 72 AIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
A E+IH SLVHDDI+D + RRG PTVH +G +AILAGD LF+++ ++
Sbjct: 70 HRRLAEITEIIHTASLVHDDILDESDVRRGIPTVHSDFGTKIAILAGDFLFAQSSWYLAN 129
Query: 132 AEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAK 191
E +V++ I K + EG+ + + +++EEY+ KT +L AS+K
Sbjct: 130 LE-----SLEVVKLISKVITDFAEGEIRRGLNQFKVDLTLEEYLEKSFYKTASLLAASSK 184
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIV 251
++ + L +GR++G+AFQI DD+LD + E+LGKP SD++KG T V
Sbjct: 185 AAALLSHVDLTVANDLYNYGRHLGLAFQIVDDILDFTSSTEELGKPSCSDLKKGNLTAPV 244
Query: 252 AHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIA 311
E E + + + + K + +++++E +I+ +A
Sbjct: 245 LFALEQNSE-----LIPLIQRQFSEPK-----------DFEYTLQIVEETKAIEKTRELA 288
Query: 312 RELVEKANEALNVLPESRARKDLELLASFMVEREY 346
E + A + L LP S +++ L+L+ +++ER Y
Sbjct: 289 MEHAQVAIQCLENLPPSSSKEALKLITKYVLERLY 323
>pir||D71651 octaprenyl-diphosphate synthase (ispB) RP479 - Rickettsia
prowazekii >gi|3861034|emb|CAA14934.1| (AJ235272)
OCTAPRENYL-DIPHOSPHATE SYNTHASE (ispB) [Rickettsia
prowazekii]
Length = 327
Score = 143 bits (358), Expect = 2e-33
Identities = 88/317 (27%), Positives = 163/317 (50%), Gaps = 18/317 (5%)
Query: 32 EKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDD 91
+ + +++ + ++ AGGKRIRP + + + I A A+E IH +L+HDD
Sbjct: 27 KSDAELIEKVGKYLVEAGGKRIRPLLTIITAKMFDYKGNNHIKLASAVEFIHAATLLHDD 86
Query: 92 IMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASN 151
++D RR KPT + +WG +IL GD LFS++F+ + + K + + KAS
Sbjct: 87 VVDNSTLRRFKPTANVIWGSKTSILVGDFLFSQSFKLMVASGC-----IKAMNVLAKASV 141
Query: 152 ELCEGQALDL-EFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRW 210
+ EG+ + L + R +++I+EY +++ KT LF A+ +VG I+ + + + + +
Sbjct: 142 IISEGEVVQLVKLNERRIITIDEYQQIVKSKTAELFGAACEVGAIIAEQVDRVSKDVQNF 201
Query: 211 GRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVF 270
GR +G FQ+ DD+LD + ++++GK +G D +GK TL + + E+ K+ +L+
Sbjct: 202 GRLLGTIFQVIDDLLDYLGSDKQVGKNIGDDFLEGKVTLPLIFLYHKL-EQDKQLWLENM 260
Query: 271 GKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRA 330
K ++ K + ++ +L+ +H + L +AN LN +P
Sbjct: 261 LK----------SDKRTKDDFVKIRDLMLKHAIYNETVNYLSSLENEANNLLNKIPVQNI 310
Query: 331 RK-DLELLASFMVEREY 346
K L + F++ R Y
Sbjct: 311 YKYYLFSIIRFILYRSY 327
>dbj|BAA23157.1| (AB000835) geranyl geranyl pyrophosphate synthase [Arabidopsis
thaliana]
Length = 343
Score = 142 bits (355), Expect = 5e-33
Identities = 98/273 (35%), Positives = 146/273 (52%), Gaps = 19/273 (6%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKV--------LYEAARHYPLAGGKRIRPFVVLTA 61
E + + +AK +++ L IP V +++A R+ L+GGKR+RP + L A
Sbjct: 38 EFISYMNNKAKSINKALDNSIPLCNNSVPLWEPVLEVHKAMRYTLLSGGKRVRPMLCLVA 97
Query: 62 TEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGD 119
E VGG A+ A A+E+IH SL+ DD+ MD D RRG PT HKV+G +ILA +
Sbjct: 98 CELVGGQESTAMPAACAVEMIHAASLILDDLPCMDDDSLRRGIPTNHKVFGEKTSILASN 157
Query: 120 LLFSKAFE---AISRAEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEY 174
L S A + A + ++ E+ + ++ + +A + L GQA DL E + ++
Sbjct: 158 ALMSLAVKQTLASTSLGVTSERVLRAVQEMARAVGTEGLVAGQAADLAGERMSFKNEDDE 217
Query: 175 MRMIS----GKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIAD 230
+R + KT L +A+A VG I+G ++E IE L + R VG+ FQ+ DDVLD
Sbjct: 218 LRYLELMHVHKTAVLVEAAAVVGAIMGGGSDEEIERLKSYARCVGLMFQVMDDVLDETKS 277
Query: 231 EEKLGKPVGSDIRKGKKTLIVAHFFENADEKAK 263
E+LGK G D+ GK T +NA E AK
Sbjct: 278 SEELGKTAGKDLITGKLTYPKVMGVDNAREYAK 310
>dbj|BAA25268.1| (AB003188) component B of hexaprenyl diphosphate synthase
[Micrococcus luteus]
Length = 325
Score = 142 bits (354), Expect = 6e-33
Identities = 103/325 (31%), Positives = 163/325 (49%), Gaps = 16/325 (4%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIEL 81
V+++L+E I + + + + +AA H +GGKR+RP VL + I AV++EL
Sbjct: 17 VEKRLYECI-QSDSETINKAAHHILSSGGKRVRPMFVLLSGFLNDTQKDDLIRTAVSLEL 75
Query: 82 IHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAK 141
+H SLVHDD +D + RRG +VH + + AI G L ++A + I+ S K
Sbjct: 76 VHMASLVHDDYIDNSDMRRGNTSVHIAFDKDTAIRTGHFLLARALQNIATINNS-----K 130
Query: 142 VLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENE 201
+ K E+C G+ + VS Y+R I+ KT L +AS +G + +E
Sbjct: 131 FHQIFSKTILEVCFGEFDQMADRFNYPVSFTAYLRRINRKTAILIEASCHLGALSSQLDE 190
Query: 202 EYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEK 261
+ + ++G +GM++QI DD+LD +DE LGKPVGSDIR G T + N E+
Sbjct: 191 QSTYHIKQFGHCIGMSYQIIDDILDYTSDEATLGKPVGSDIRNGHITYPLMAAIANLKEQ 250
Query: 262 AKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEA 321
+K V VK +D EV + I + I+ A ++R+ +KA
Sbjct: 251 DDDKLEAV-------VKHLTSTSDD---EVYQYIVSQVKQYGIEPAELLSRKYGDKAKYH 300
Query: 322 LNVLPESRARKDLELLASFMVEREY 346
L+ L +S + LE + M++R Y
Sbjct: 301 LSQLQDSNIKDYLEEIHEKMLKRVY 325
>pir||G72410 geranyltranstransferase - Thermotoga maritima (strain MSB8)
>gi|4980655|gb|AAD35254.1|AE001701_7 (AE001701)
geranyltranstransferase [Thermotoga maritima]
Length = 272
Score = 141 bits (353), Expect = 8e-33
Identities = 94/251 (37%), Positives = 143/251 (56%), Gaps = 13/251 (5%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIEL 81
V+E++ E++ + EA + GGKRIRP +VLT E +G K + AVA+EL
Sbjct: 6 VEERIREILRPGWDLLTEEAMLYSATVGGKRIRPLLVLTLGEDLGVEEEKLLDVAVAVEL 65
Query: 82 IHNYSLVHDDIMDMD--ETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
H SL+HDD+ +D + RRGKP+ H+ +G ++A+LAGD LF AF IS+
Sbjct: 66 FHTASLIHDDLPPIDNADFRRGKPSCHRTYGEDIALLAGDGLFFLAFSQISKI-----GN 120
Query: 140 AKVLETIVKASNELCEGQALDLEFENREM-VSIEEYMRMISGKTGALFDASAKVGGIVGT 198
+K+ E + + +L G+A+D+EFE R+M VS E RM + KTGALF I+
Sbjct: 121 SKIFEEFSETAYKLLLGEAMDVEFERRKMEVSQEMVERMYAFKTGALFAFCFSAPFILKG 180
Query: 199 ENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENA 258
++ ++ L G G+AFQI+DD+ D++ EK+GK +G D K TL+ + A
Sbjct: 181 KDHTKMKLL---GEKFGVAFQIYDDLKDILGSFEKVGKDLGKDTE--KVTLVKKVGIQKA 235
Query: 259 DEKAKEKFLKV 269
E A + + +V
Sbjct: 236 REMADKYYEEV 246
>pir||T50879 phytoene synthase [imported] - Rubrivivax gelatinosus
>gi|7416783|dbj|BAA94032.1| (AB034704) phytoene synthase
[Rubrivivax gelatinosus]
Length = 310
Score = 140 bits (350), Expect = 2e-32
Identities = 106/292 (36%), Positives = 147/292 (50%), Gaps = 26/292 (8%)
Query: 35 PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG-NALKAIYPAVAIELIHNYSLVHDDIM 93
P L A RH GG RIRP + + A G + A A AIELIH SLVHDD+
Sbjct: 24 PPKLAAAIRHAVFPGGARIRPQLCIAVAMANGDTDPALADAAASAIELIHCASLVHDDLP 83
Query: 94 DMDE--TRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE-ISPEKKAKVLETIVKAS 150
D+ TRRG+P+VHK +G +A+LAGD L AF+ + A PE+ A VL+T+ +
Sbjct: 84 CFDDAPTRRGQPSVHKAYGERLAVLAGDALIVTAFQTLGAAGGRHPERMAHVLQTVARGV 143
Query: 151 NE---LCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEAL 207
+ GQA + E V++ +Y R KTGALF A+ G + E AL
Sbjct: 144 GTPLGIIAGQAWECE----PRVALSDYQR---AKTGALFAAATAAGAQASGGDGETWRAL 196
Query: 208 SRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFL 267
W +G A+Q+ DDV D +AD E+LGKPVG D+ G+ + + H A E E+ +
Sbjct: 197 GDW---LGEAYQVADDVRDALADPEQLGKPVGRDVALGRPSAAIQHGLVGAVEHF-ERLV 252
Query: 268 KVFGKYAGDVKGKGIIEEDVKAEVMEA--------IELLKEHGSIDYASRIA 311
+ D KG G++ + V+ E IE L E ++ A R A
Sbjct: 253 QGAIDVIPDCKGAGMLRQIVRMEAERLVPKAWCANIEALAERAAVRAAERSA 304
>pir||D82778 geranyltranstransferase (farnesyl-diphosphate synthase) XF0661
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9105539|gb|AAF83471.1|AE003910_7 (AE003910)
geranyltranstransferase (farnesyl-diphosphate synthase)
[Xylella fastidiosa]
Length = 291
Score = 140 bits (350), Expect = 2e-32
Identities = 87/244 (35%), Positives = 135/244 (54%), Gaps = 6/244 (2%)
Query: 9 DELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGN 68
+ LF R ++R E+ IP + P+ L+ A R+ L+ GKRIRP +V A +
Sbjct: 3 EALFTRWRQRTDSYLERTLS-IPTQAPQRLHAAMRYTVLSRGKRIRPLLVYAAGHLFHVD 61
Query: 69 ALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAF 126
PA A+ELIH YSLVHDD+ MD D RRG+PTVH + AIL GD L + AF
Sbjct: 62 EPLLDVPAAAVELIHAYSLVHDDLPAMDDDLLRRGRPTVHIAFDEATAILTGDALQTLAF 121
Query: 127 EAISRAEISPEKKAKVLETIVKASNE--LCEGQALDLEFENREMVSIEEYMRMISGKTGA 184
E ++ A + L+T+ A+ +C GQA+D++ + +++ M + K+G
Sbjct: 122 ECLADAPSDTSLRIAWLQTLTHAAGVAGMCGGQAIDIDATGQSQ-TLKALEAMHALKSGT 180
Query: 185 LFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRK 244
L A+ ++G + G + E + +L + +G+AFQ+ DD+LD+ + E+LGK G D +
Sbjct: 181 LMRAAVRMGALAGDPSAEDLHSLDTFAATLGLAFQVRDDILDIESSSEQLGKTAGKDAIQ 240
Query: 245 GKKT 248
K T
Sbjct: 241 QKST 244
>pir||E81796 geranyltranstransferase (EC 2.5.1.10) NMA2226 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380845|emb|CAB85437.1| (AL162758)
geranyltranstransferase [Neisseria meningitidis Z2491]
Length = 298
Score = 140 bits (349), Expect = 2e-32
Identities = 97/245 (39%), Positives = 139/245 (56%), Gaps = 12/245 (4%)
Query: 16 KERAKLVDEKLFELIPEKE---PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKA 72
++RA+ E L E E P L+EA R+ L GGKR+RP +VL A+E +G +A
Sbjct: 11 QQRAQAQTELLLERFLPSENEIPHTLHEAMRYAALDGGKRLRPMLVLAASE-LGEAVHEA 69
Query: 73 IYPAVA-IELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAI 129
+ A+A IE+IH YSLVHDD+ MD D RRGKPT H +G A+L GD L ++AF+ +
Sbjct: 70 VGQAMAAIEMIHAYSLVHDDMPAMDNDSLRRGKPTCHVKYGEATALLTGDALQTQAFDVL 129
Query: 130 SR-AEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALF 186
SR E+ ++ +L + KA S + GQA+DL ++M + +M S KTGAL
Sbjct: 130 SRPTELPAARQLAMLSVLAKAGGSMGMAGGQAIDLANVGKQMAQ-TDLEQMHSLKTGALI 188
Query: 187 DASAKVGGI-VGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
A+ +G + +E+ + L + +G+AFQ+ DDVLD AD LGK G D
Sbjct: 189 RAAVLLGAMSCPNLSEDSLAVLDDYAAKLGLAFQVIDDVLDCEADTATLGKTAGKDADND 248
Query: 246 KKTLI 250
K T +
Sbjct: 249 KPTYV 253
>gb|AAF25540.1|AF104994_10 (AF104994) geranyl transferase [Streptomyces coelicolor A3(2)]
Length = 386
Score = 139 bits (347), Expect = 4e-32
Identities = 108/307 (35%), Positives = 147/307 (47%), Gaps = 22/307 (7%)
Query: 46 PLAG--GKRIRPFVVLTATEAVGGNALKA--IYPAVAIELIHNYSLVHDDIMDMDETRRG 101
P AG GK IRP +VLTA A+GG +A + A A+EL+HN++L+HDD+MD D TRR
Sbjct: 92 PAAGNAGKAIRPALVLTAAAALGGPGARAAAVRAAAAVELVHNFTLLHDDVMDRDATRRH 151
Query: 102 KPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDL 161
+PT V+G AILAGD L + A + A+ P A + ELCEGQ D
Sbjct: 152 RPTAWTVFGDADAILAGDALQALALRLFA-ADPHPASAAAATR-LADCVMELCEGQHADT 209
Query: 162 EFEN--REMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQ 219
E + V+++E + M KTGAL + VG + E +EAL +GR GMAFQ
Sbjct: 210 AMERPPPDEVTLDETLVMAEAKTGALLGCACAVGALYAGAATEDVEALDAFGREPGMAFQ 269
Query: 220 IWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKG 279
+ DDV+ + D + D+ KK+L V + A E G Y
Sbjct: 270 LIDDVIGIWGDPAPHRQAGRCDLAARKKSLPVVAALTSGTPAAAELAELYTGPY------ 323
Query: 280 KGIIEEDVKAEVMEAIELLKEH-GSIDYASRIARELVEKA-NEALNVLPESRARKDLELL 337
D E +E L E G D+A A + + +A E +PE A L L
Sbjct: 324 ------DENKEDLERTALAVERAGGRDWAQAQAADRMARAMQELARAVPEPEAAGGLLAL 377
Query: 338 ASFMVER 344
A F+ R
Sbjct: 378 AEFVTRR 384
>pir||T05674 farnesyltranstransferase homolog F20M13.20 - Arabidopsis thaliana
>gi|4467133|emb|CAB37502.1| (AL035540) geranylgeranyl
pyrophosphate synthase-related protein [Arabidopsis
thaliana] >gi|7270829|emb|CAB80510.1| (AL161593)
geranylgeranyl pyrophosphate synthase-related protein
[Arabidopsis thaliana]
Length = 326
Score = 138 bits (344), Expect = 1e-31
Identities = 97/263 (36%), Positives = 141/263 (52%), Gaps = 26/263 (9%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLA-GGKRIRPFVVLTATEAVGGNALKAIYPAVAIE 80
+++KL E IP K P +YEA R+ LA G KR P + + A E GG+ L A A A+E
Sbjct: 58 INQKLDEAIPVKHPAGIYEAMRYSVLAQGAKRAPPVMCVAACELFGGDRLAAFPTACALE 117
Query: 81 LIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE-AISRAEISPE 137
++H SL+HDD+ MD D RRGKP+ H V+G MAILAGD LF AF+ +S
Sbjct: 118 MVHAASLIHDDLPCMDDDPVRRGKPSNHTVYGSGMAILAGDALFPLAFQHIVSHTPPDLV 177
Query: 138 KKAKVLETIVK-----ASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKV 192
+A +L I + S + GQ +DLE + ++E K GA+ + SA
Sbjct: 178 PRATILRLITEIARTVGSTGMAAGQYVDLEGGPFPLSFVQE------KKFGAMGECSAVC 231
Query: 193 GGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVA 252
GG++G E+ +++L R+GR VGM +Q+ DD I +++K G++ KG +
Sbjct: 232 GGLLGGATEDELQSLRRYGRAVGMLYQVVDD----ITEDKKKSYDGGAE--KG-----MM 280
Query: 253 HFFENADEKAKEKFLKVFGKYAG 275
E EKAK++ KY G
Sbjct: 281 EMAEELKEKAKKELQVFDNKYGG 303
>dbj|BAA96457.1| (AB028044) farnesyl diphosphate synthase [Rhodobacter sphaeroides]
Length = 256
Score = 138 bits (343), Expect = 1e-31
Identities = 90/243 (37%), Positives = 135/243 (55%), Gaps = 15/243 (6%)
Query: 45 YPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGK 102
Y + GGKR+R F+VL + G A+ A +IE +H YSLVHDD+ MD D+ RRG
Sbjct: 3 YAVQGGKRLRGFLVLESARLHGIAPEAAVSAAASIEALHAYSLVHDDMPCMDDDDLRRGL 62
Query: 103 PTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEK-KAKVLETIVKASNE--LCEGQAL 159
PTVH+ W A+LAGD L + AFE ++ + P + +++ ++ KAS + GQAL
Sbjct: 63 PTVHRKWDECTAVLAGDALQTLAFELLADPALGPAAVRIELVASLAKASGAEGMVLGQAL 122
Query: 160 DLEFENREM-VSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAF 218
D+ E + +++++ + +GKTGAL SA+ G I+G + L R+ +G+AF
Sbjct: 123 DIAAETAAVPLTLDQITHLQAGKTGALIRWSAEAGAILGQADR---VPLRRYATALGLAF 179
Query: 219 QIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAK------EKFLKVFGK 272
QI DD+LD+ D EK GK + D GK T + + A +A+ E L +G
Sbjct: 180 QIADDILDVEGDAEKAGKRLQKDAEAGKATFVSLLGLDGAKARARALVEDAEAALAPYGP 239
Query: 273 YAG 275
AG
Sbjct: 240 EAG 242
>pir||E81400 polyprenyl synthetase (EC 2.5.1.-) Cj0541 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968009|emb|CAB75177.1| (AL139075) polyprenyl
synthetase [Campylobacter jejuni]
Length = 297
Score = 137 bits (342), Expect = 2e-31
Identities = 100/326 (30%), Positives = 173/326 (52%), Gaps = 33/326 (10%)
Query: 24 EKLFELIPEKEPKVLYEAARHY--PLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIEL 81
+K+ ELI + ++ YE + + GK++R ++L A+ + A AIEL
Sbjct: 2 QKIDELIKQFLQELGYEPILNMLSNVKSGKKLRSKLLL----AIADESEIAFKICAAIEL 57
Query: 82 IHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAK 141
IH SL+HDDI+D E RRG +V+ +G A++ GD+L+SKAF +S+ + A+
Sbjct: 58 IHLASLLHDDIIDESELRRGARSVNAEFGTKNALMLGDILYSKAFYELSKMD------AR 111
Query: 142 VLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIV-GTEN 200
I A +L G+ +D++ + ++ E Y++MI KT L +ASA+ G I+ G
Sbjct: 112 FASIISDAVVKLAIGELMDVDLGEKFNINKEAYLKMIYNKTAVLIEASARCGAILAGLYE 171
Query: 201 EEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADE 260
+++ E +G+N+G+AFQ+ DD+LD+ +DE+ LGKP +D ++GK TL + +EN E
Sbjct: 172 KDFAE----YGKNLGLAFQMIDDILDIKSDEKILGKPAMNDFKEGKTTLPYIYLYENLQE 227
Query: 261 KAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANE 320
+ + +F K + E+ K + E E +++ A A+ +KA +
Sbjct: 228 QDRIYLQTLF---------KKDLNENEKEWLKTKFE---EQKALEKAILEAKTYAKKARK 275
Query: 321 ALNVLPESRARKDLELLASFMVEREY 346
A+ E L + M++RE+
Sbjct: 276 AI----EKYDNNKLNDIIKAMIDREF 297
>gb|AAB41847.1| (U61168) spore germination protein C3 [Bacillus firmus]
Length = 288
Score = 136 bits (338), Expect = 5e-31
Identities = 87/256 (33%), Positives = 137/256 (52%), Gaps = 10/256 (3%)
Query: 7 KYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATE--A 64
K +++ + + +++++L E + VL A+ H AGGKRIRP VL A +
Sbjct: 9 KLADIYMQFQSDITIIEQEL-EASVQARHDVLKNASTHLLKAGGKRIRPVFVLLAAKFGT 67
Query: 65 VGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSK 124
+ LK I AV +EL+H SLVHDD++D E RRGK TV W +A+ G+ +F+K
Sbjct: 68 YDIHVLKNI--AVPLELVHMASLVHDDVIDDAELRRGKRTVKSQWDNKVAMYTGNYIFAK 125
Query: 125 AFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGA 184
A EA + + P + T+V E+C G+ + + ++ Y+R I KT
Sbjct: 126 AVEASAYFD-HPRVHQVLSNTLV----EMCIGEVEQIRDQYNWGQNLRVYLRRIKRKTAL 180
Query: 185 LFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRK 244
L S ++G + + + L +G NVGM+FQI DD+LD + E++LGKP G D+R+
Sbjct: 181 LIAVSCELGALAADADPVIQKHLYNFGYNVGMSFQITDDILDFVGTEKQLGKPAGGDLRQ 240
Query: 245 GKKTLIVAHFFENADE 260
G TL + + +E
Sbjct: 241 GNVTLPALYAMHHDEE 256
>gb|AAA81879.1| (L40577) geranylgeranyl pyrophosphate synthase-related protein
[Arabidopsis thaliana]
Length = 326
Score = 135 bits (337), Expect = 6e-31
Identities = 96/263 (36%), Positives = 140/263 (52%), Gaps = 26/263 (9%)
Query: 22 VDEKLFELIPEKEPKVLYEAARHYPLAGG-KRIRPFVVLTATEAVGGNALKAIYPAVAIE 80
+++KL E IP K P +YEA R+ L G KR P + + A E GG+ L A A A+E
Sbjct: 58 INQKLDEAIPVKHPAGIYEAMRYSVLPQGPKRAPPVMCVAACELFGGDRLAAFPTACALE 117
Query: 81 LIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE-AISRAEISPE 137
++H SL+HDD+ MD D RRGKP+ H V+G MAILAGD LF AF+ +S
Sbjct: 118 MVHAASLIHDDLPCMDDDPVRRGKPSNHTVYGSGMAILAGDALFPLAFQHIVSHTPPDLV 177
Query: 138 KKAKVLETIVK-----ASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKV 192
+A +L I + S + GQ +DLE + ++E K GA+ + SA
Sbjct: 178 PRATILRLITEIARTVGSTGMAAGQYVDLEGGPFPLSFVQE------KKFGAMGECSAVC 231
Query: 193 GGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVA 252
GG++G E+ +++L R+GR VGM +Q+ DD I +++K G++ KG +
Sbjct: 232 GGLLGGATEDELQSLRRYGRAVGMLYQVVDD----ITEDKKKSYDGGAE--KG-----MM 280
Query: 253 HFFENADEKAKEKFLKVFGKYAG 275
E EKAK++ KY G
Sbjct: 281 EMAEELKEKAKKELQVFDNKYGG 303
>pir||S76966 geranylgeranyl pyrophosphate synthase crtE homolog - Synechocystis
sp. (strain PCC 6803)
Length = 323
Score = 135 bits (337), Expect = 6e-31
Identities = 101/338 (29%), Positives = 171/338 (49%), Gaps = 27/338 (7%)
Query: 11 LFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEA-VGGNA 69
LF + + +L+ + L L+ + P +L AA H AGGKR+RP +VL + A +
Sbjct: 7 LFAPVDQDLRLLTDNLKRLVGARHP-ILGAAAEHLFEAGGKRVRPAIVLLVSRATLLDQE 65
Query: 70 LKAIYPAVA--IELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
L A + +A E+IH SLVHDD++D + RR PTV+ ++ +A+LAGD LF+++
Sbjct: 66 LTARHRRLAEITEMIHTASLVHDDVVDEADLRRNVPTVNSLFDNRVAVLAGDFLFAQSSW 125
Query: 128 AISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFD 187
++ + +V++ + + + EG+ L +E Y+ KT +L
Sbjct: 126 YLANLD-----NLEVVKLLSEVIRDFAEGEILQSINRFDTDTDLETYLEKSYFKTASLIA 180
Query: 188 ASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKK 247
SAK G++ + + L +G+++G+AFQI DD+LD + E LGKP GSD+ G
Sbjct: 181 NSAKAAGVLSDAPRDVCDHLYEYGKHLGLAFQIVDDILDFTSPTEVLGKPAGSDLISGNI 240
Query: 248 TLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKA-EVMEAIELLKEHGSIDY 306
T A EK+ + GK I E +A ++ +A+EL+++ I
Sbjct: 241 TAPALF--------AMEKY---------PLLGKLIEREFAQAGDLEQALELVEQGDGIRR 283
Query: 307 ASRIARELVEKANEALNVLPESRARKDLELLASFMVER 344
+ +A + A + L+VL S R+ L L +++ R
Sbjct: 284 SRELAANQAQLARQHLSVLEMSAPRESLLELVDYVLGR 321
>dbj|BAA96458.1| (AB028046) farnesyl diphosphate synthase [Rhodobacter capsulatus]
Length = 288
Score = 135 bits (336), Expect = 8e-31
Identities = 90/259 (34%), Positives = 141/259 (53%), Gaps = 17/259 (6%)
Query: 42 ARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDETR 99
A Y GGKR+R F+ + + G + +A+ A+A+E +H YSLVHDD+ MD D+ R
Sbjct: 32 AMAYAAQGGKRLRAFLAIESAAIHGISMEQAMPAALAVEALHAYSLVHDDMPCMDNDDLR 91
Query: 100 RGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEI-SPEKKAKVLETIVKASNE--LCEG 156
RG PTVH+ W A+LAGD L + AFE + + S E + ++ + +AS + G
Sbjct: 92 RGLPTVHRKWDEATAVLAGDALQTLAFELCTDPVLGSAENRVALVAALAQASGAEGMVYG 151
Query: 157 QALDLEFENREM-VSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVG 215
QALD+ E + ++++E +R+ +GKTGAL +A+ G I+ + + A + +G
Sbjct: 152 QALDIAAETAAVPLTLDEIIRLQAGKTGALISFAAQAGAIIAGADRALLAA---YATALG 208
Query: 216 MAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKA------KEKFLKV 269
+AFQI DD+LD+ DEE GK +G D K T + A +A E L
Sbjct: 209 LAFQIADDILDVEGDEEAAGKRLGKDAEAHKATFVSLLGLPGAKARAADLVAEAEAALAP 268
Query: 270 FGKYAGDVK--GKGIIEED 286
+G+ A ++ + +IE D
Sbjct: 269 YGEAAATLRACARYVIERD 287
>gb|AAG20290.1| (AE005103) putative isopentenyl pyrophosphate isomerase; Fps
[Halobacterium sp. NRC-1]
Length = 300
Score = 135 bits (336), Expect = 8e-31
Identities = 87/247 (35%), Positives = 124/247 (49%), Gaps = 30/247 (12%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG------- 67
++ R +++++ E + EP L + H LAGGKR+RP + + EA GG
Sbjct: 4 VEARRAAIEQRITEAVGGVEPTELGDQLEHVVLAGGKRVRPTLTVLVCEAAGGAVWTGAA 63
Query: 68 -------NAL------KAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMA 114
NA A+ AV +EL+HN SLV DDI+D E RRG + +G
Sbjct: 64 EAAAVRENAALSAGGEDALDYAVGVELVHNASLVVDDIIDRSELRRGSASAWAEYGYGPG 123
Query: 115 ILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEY 174
I+A D L +AF SR + +E + + EL EG+A++L + EY
Sbjct: 124 IVASDGLLGEAFALFSR-------DPRAMECVTDSLVELGEGEAIELVARPE---TEREY 173
Query: 175 MRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKL 234
M + KTGALF A+A++G I + +E + VG+AFQI DDVLD AD + L
Sbjct: 174 MELARRKTGALFRAAAELGAIAADADGRAVERFGEYAERVGVAFQIRDDVLDATADSDAL 233
Query: 235 GKPVGSD 241
GKP G D
Sbjct: 234 GKPAGVD 240
>pir||F81217 geranyltranstransferase NMB0261 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7225485|gb|AAF40715.1|
(AE002383) geranyltranstransferase [Neisseria
meningitidis MC58]
Length = 259
Score = 131 bits (326), Expect = 1e-29
Identities = 87/215 (40%), Positives = 125/215 (57%), Gaps = 9/215 (4%)
Query: 43 RHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVA-IELIHNYSLVHDDI--MDMDETR 99
R+ L GGKR+RP +VL A+E +G +A+ A+A IE+IH YSLVHDD+ MD D R
Sbjct: 2 RYAALDGGKRLRPMLVLAASE-LGEAVHEAVEQAMAAIEMIHVYSLVHDDMPAMDNDSLR 60
Query: 100 RGKPTVHKVWGINMAILAGDLLFSKAFEAISR-AEISPEKKAKVLETIVKA--SNELCEG 156
RGKPT H +G A+L GD L ++AF+ +SR E+ ++ +L + KA S + G
Sbjct: 61 RGKPTCHIKYGEATALLTGDALQTQAFDVLSRPTELPAARQLAMLSVLAKAGGSRGMAGG 120
Query: 157 QALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTE-NEEYIEALSRWGRNVG 215
QA+DL ++MV + +M S KTGAL A+ +G + ++ + L + +G
Sbjct: 121 QAIDLANVGKQMVQ-ADLEQMHSLKTGALIRAAVLLGATACPDLSDAELSVLDAYAAKLG 179
Query: 216 MAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLI 250
+AFQ+ DDVLD AD LGK G D K T +
Sbjct: 180 LAFQVIDDVLDCEADTATLGKTAGKDADNDKPTYV 214
>gi|11465411 unknown; prenyl transferase [Cyanidium caldarium]
>gi|6466314|gb|AAF12896.1|AF022186_18 (AF022186)
unknown; prenyl transferase [Cyanidium caldarium]
Length = 323
Score = 129 bits (322), Expect = 4e-29
Identities = 98/335 (29%), Positives = 167/335 (49%), Gaps = 29/335 (8%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA-LKAI 73
+KE +++ L +LI P +L AA+H + K+IRP +VL +A+ N +K
Sbjct: 11 VKEDLLNIEQTLNKLIKVNNP-ILSAAAKHLLIVESKKIRPAIVLLVAKAIDKNKKIKTS 69
Query: 74 YPAVA--IELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
+A E+IH +L+HDD++D RRG +V+K +G +A+ AGD LF+++ ++
Sbjct: 70 QQRLAEVTEIIHTATLLHDDVVDESIIRRGTKSVNKTFGNKIAVFAGDFLFAQSSWYLAN 129
Query: 132 AEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAK 191
+V++ I K +L EG+ + SI +Y+ KT +L AS K
Sbjct: 130 IN-----NLEVVKAISKVITDLAEGELQQNLTQFNTYYSIIKYLEKSFNKTASLIAASCK 184
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIV 251
++ ++ +G+N+G+AFQI DD+LD+ + LGK SD++ G T V
Sbjct: 185 SCCLLSDFDQSLNSKFYNYGKNLGLAFQIIDDILDITSSSTALGKMTTSDLKLGNLTAPV 244
Query: 252 AHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDV--KAEVMEAIELLKEHGSIDYASR 309
A K K+F IIE + K+++ EAI ++KE +I+ +
Sbjct: 245 LF--------ALTKNSKLF----------KIIEREFCEKSDISEAINIIKETNAIEESFD 286
Query: 310 IARELVEKANEALNVLPESRARKDLELLASFMVER 344
+A E +E A ++ LP S + L +A ++ R
Sbjct: 287 LAYEHIEAAINSIKDLPTSSEKDSLIEIAYDLLNR 321
>dbj|BAA96459.1| (AB028047) farnesyl diphosphate synthase [Rhodovulum sulfidophilum]
Length = 289
Score = 129 bits (321), Expect = 5e-29
Identities = 92/277 (33%), Positives = 144/277 (51%), Gaps = 17/277 (6%)
Query: 15 IKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIY 74
+K A+ ++ +L E + + + +A R Y ++GGKR+R F+VL + A+
Sbjct: 6 LKSAAERIETRLTEALAGAADQPVTQAMR-YAVSGGKRLRGFLVLESAALYDIAPEAAVD 64
Query: 75 PAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRA 132
A A+E +H YSLVHDD+ MD D+ RRG+PTVH W A+L GD L + AFE +S
Sbjct: 65 AAAAVEALHAYSLVHDDMPCMDDDDLRRGQPTVHVKWDDGTALLTGDALQTLAFELLSAP 124
Query: 133 EISPEKKAKV--LETIVKAS--NELCEGQALDLEFENR-EMVSIEEYMRMISGKTGALFD 187
P+ ++ + ++ +AS + + GQA D+ E ++++E + + KTGAL
Sbjct: 125 ACHPDPAVRIDLVASLARASGIDGMVLGQAQDIAAETAGRSLTLDEITELQANKTGALIR 184
Query: 188 ASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKK 247
SA+ G + + I L+ + +G+AFQI DD+LD+ D K GK V D GK
Sbjct: 185 WSAEAGARLARAD---IAPLTAYSTALGLAFQIADDILDVEGDAAKTGKRVHKDAEAGKA 241
Query: 248 TLIVAHFFENADEKA------KEKFLKVFGKYAGDVK 278
T + + A +A E L FG A +K
Sbjct: 242 TFVSLLGLDGARARALALVEEAEAALDPFGGRADPLK 278
>pir||C75400 geranylgeranyl diphosphate synthase - Deinococcus radiodurans
(strain R1) >gi|6459152|gb|AAF10966.1|AE001985_3
(AE001985) geranylgeranyl diphosphate synthase
[Deinococcus radiodurans]
Length = 329
Score = 126 bits (314), Expect = 3e-28
Identities = 106/337 (31%), Positives = 167/337 (49%), Gaps = 32/337 (9%)
Query: 25 KLFELIPEKE--PKV--LYEAARHYPLAGGKRIRPFVVLTATEAVGGNAL-----KAIYP 75
++ L+PE P++ Y R YP GGK IR ++L + A G + A++
Sbjct: 8 RVLSLLPETSATPELARFYALLRDYPQRGGKGIRSELLLASARAHGLSESDTGWESALWL 67
Query: 76 AVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEIS 135
A A+EL N+ LVHDDI D E RRG+P +H + G+ +A+ GD L + + A+ +A +
Sbjct: 68 AAALELFQNWVLVHDDIEDDSEERRGRPALHHLCGMPVALNVGDALHAYMWAAVGKANV- 126
Query: 136 PEKKAKVLETIVKASNELCEGQALDLEF-ENREM-VSIEEYMRMISGKTG-ALFDASAKV 192
P + L+ + + + EGQ LDL + E RE + +Y++M+ KT ++
Sbjct: 127 PGAFEEFLQMVYRTA----EGQHLDLAWVEGREWGLRPADYLQMVGLKTAHYTVIVPLRL 182
Query: 193 GGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVA 252
G + + +A + G +G AFQI DDVL+L D K GK +G D+ +GK+TLIV
Sbjct: 183 GALAAGMAPQ--DAFTPAGLALGTAFQIRDDVLNLAGDPVKYGKEIGGDLLEGKRTLIVL 240
Query: 253 HFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSI----DYAS 308
+ A + K FL ++ D K +I+ E L E GS+ DYA
Sbjct: 241 DWLTTAPDDRKAIFLDQMRRHRAD-KDPAVID--------EIHRWLLESGSVEAAQDYAQ 291
Query: 309 RIARELVEKANEALNVLPESRARKDLELLASFMVERE 345
A E ++ +AL P+++A L + RE
Sbjct: 292 AQAAEGLDLLEKALADAPDAQAAAALLASVRELATRE 328
>gb|AAG28699.1|AF272737_2 (AF272737) CrtE [Streptomyces griseus]
Length = 425
Score = 125 bits (311), Expect = 7e-28
Identities = 93/311 (29%), Positives = 150/311 (47%), Gaps = 25/311 (8%)
Query: 45 YPLAGGKRIRPFVVLTATEAVGG-NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKP 103
+ L GGKR+RP ++ + G + A+ VA+ELI + +L+HDD+MD RRGKP
Sbjct: 79 FTLDGGKRVRPRLLWWGMRSCGAADTTAALRLGVALELIQSCALIHDDVMDRSRLRRGKP 138
Query: 104 TVH----------------KVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIV 147
VH +G + A+LAGDL + A + ++ +S ++ ++
Sbjct: 139 AVHIGLAERAGYSPDSGRGSAFGASAAVLAGDLALAWADDTVAETALSAVQRRRIGPLWR 198
Query: 148 KASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL-FDASAKVGGIVGTENEEYIEA 206
E+ GQ LDL + R S+E+ +R K+ + + +G + +E +A
Sbjct: 199 TMRTEMVAGQYLDLRGQVRGGSSVEQALRTACLKSASYSVERPLALGAALAGADEATTDA 258
Query: 207 LSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKF 266
L GR G+AFQ+ DD+L + D E GKP G DIR+GK T ++ A+ ++
Sbjct: 259 LRSAGRCAGIAFQLRDDLLGVFGDPELTGKPSGDDIREGKSTYLLPVARRWAEPAGNKQS 318
Query: 267 LKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLP 326
L V G++ G G + +ED+ E +L+E G+ + R A L + A L
Sbjct: 319 LAVLGRFPG---GGNLAKEDLP----EVRGVLEETGARAHVERKADPLRDHALGRLAQAV 371
Query: 327 ESRARKDLELL 337
E A +LL
Sbjct: 372 EVEAHGGRQLL 382
>pir||T50750 farnesyltranstransferase (EC 2.5.1.29) crtE [imported] -
Rhodobacter sphaeroides >gi|6690726|gb|AAF24294.1|
(AF195122) CrtE [Rhodobacter sphaeroides]
Length = 288
Score = 123 bits (307), Expect = 2e-27
Identities = 83/233 (35%), Positives = 119/233 (50%), Gaps = 9/233 (3%)
Query: 35 PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNA-LKAIYPAVAIELIHNYSLVHDDIM 93
P L A + GG RIRP ++L+ A G + + + AVA+ELIH SLVHDD+
Sbjct: 24 PSKLATALDYAVTPGGARIRPTLLLSVATACGDDRPVLSDAAAVALELIHCASLVHDDLP 83
Query: 94 DMD--ETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASN 151
D E RRGKPTVH+ + +AIL GD L FE ++RA ++A L T +
Sbjct: 84 CFDDAEIRRGKPTVHRAYSEPLAILTGDSLIVMGFEVLARAAADQPQRALQLVTALAVRT 143
Query: 152 ELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWG 211
+ G +E+ +++ Y R KTGALF A+ ++G I E E L G
Sbjct: 144 GMPMGICAGQGWESESQINLSAYHR---AKTGALFIAATQMGAIAAGYEAEPWEEL---G 197
Query: 212 RNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKE 264
+G AFQ+ DD+ D + D E LGKP G D + + + E A ++ K+
Sbjct: 198 ARIGEAFQVADDLRDALCDAETLGKPAGQDEIHARPNAVREYGVEGAAKRLKD 250
>emb|CAC12434.1| (AL445067) geranylgeranyl pyrophosphate synthase related protein
[Thermoplasma acidophilum]
Length = 354
Score = 123 bits (305), Expect = 4e-27
Identities = 95/361 (26%), Positives = 167/361 (45%), Gaps = 40/361 (11%)
Query: 10 ELFNRIKERAKLVDEKLFELIPEKEPKV-------LYEAARHYPLAGGKRIRPFVVLTAT 62
E N K R +DE++ KE + + R Y GGKR+RP ++
Sbjct: 10 ETINNYKLR---IDERISRFFDRKEAETKDDLSRRVIRMIREYTEGGGKRLRPIFLVLGY 66
Query: 63 EAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVH-KVW------------ 109
+++IEL +Y L+HDD++D + RRGKP++H ++W
Sbjct: 67 RLFADENNAIFDASISIELAQSYLLIHDDVIDDSDLRRGKPSMHIRLWRSFFPESEKGKK 126
Query: 110 -GINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREM 168
G +AI+AGDL + A E++ ++ P + K GQ LD+
Sbjct: 127 MGEGLAIVAGDLAETYAHESLINSDFDPSLLLLADMELTKTIEMTGYGQFLDVVSGTLND 186
Query: 169 VSIEEYMRMISGKTGAL-FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDL 227
+ +R+ KT + +G ++ +++ ++ L +GR +G+AFQ+ DD+L L
Sbjct: 187 FRENDLIRLHLWKTARYTLEGPLAMGALLSGRHDQIMD-LRLFGRTLGIAFQLKDDILGL 245
Query: 228 IADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDV 287
DE GK + SD+ +GK+TL++ E +D + E ++ + +V
Sbjct: 246 FGDEATTGKSIYSDVNEGKRTLLMIKAMEFSDRQDAEFIDRILRR------------GNV 293
Query: 288 KAEVMEAI-ELLKEHGSIDYASRIARELVEKANEALN-VLPESRARKDLELLASFMVERE 345
E E I ++ + GS DY+ ++ LV K+ E LN + S A+ L L+ ++V R+
Sbjct: 294 TQEEFERIRNIVMKSGSYDYSVKLMDSLVAKSKEYLNRIRGNSCAKTYLSWLSDYLVARD 353
Query: 346 Y 346
+
Sbjct: 354 H 354
>gi|7657653 trans-prenyltransferase; polyprenyl pyrophosphate synthetase [Homo
sapiens] >gi|4732024|gb|AAD28559.1|AF118395_1 (AF118395)
trans-prenyltransferase [Homo sapiens]
Length = 376
Score = 122 bits (304), Expect = 5e-27
Identities = 76/227 (33%), Positives = 118/227 (51%), Gaps = 16/227 (7%)
Query: 33 KEPKV----LYEAARHYPLAGGKRIRPFVVLTATEAVG-----GNALKAIYPAVAI--EL 81
KEP + L E + +Y GK RP +V+ A ++A A+A+ E+
Sbjct: 73 KEPLISTTELKEISEYYFDVKGKAFRPIIVVLMARACNIHHNNSRHVQASQRAIALIAEM 132
Query: 82 IHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAK 141
IH SLVHDD++D +RRGK TV+K+WG A+LAGDL+ S A A++R
Sbjct: 133 IHTASLVHDDVIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARI-----GNTT 187
Query: 142 VLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENE 201
V+ + + +L G+ L L + E Y+ KT +L S K ++G +
Sbjct: 188 VISILTQVIEDLVRGEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDP 247
Query: 202 EYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
E ++G+NVG+AFQ+ DDVLD + +++GKP +D++ G T
Sbjct: 248 VVHEIAYQYGKNVGIAFQLIDDVLDFTSCSDQMGKPTSADLKLGLAT 294
>pir||B81261 geranyltranstransferase (EC 2.5.1.10) Cj1644 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6969061|emb|CAB73632.1| (AL139079)
geranyltranstransferase [Campylobacter jejuni]
Length = 281
Score = 121 bits (301), Expect = 1e-26
Identities = 74/202 (36%), Positives = 116/202 (56%), Gaps = 6/202 (2%)
Query: 48 AGGKRIRPFVVLTATEAVGGNAL-KAIYPAVAIELIHNYSLVHDDIMDMDET--RRGKPT 104
AGGK R ++L+ ++ L +A+ A+A+E IH YSL+HDD+ MD RRG PT
Sbjct: 35 AGGKHFRAQLLLSVVQSNKPELLNQALDVALALEFIHTYSLIHDDLPAMDNADFRRGIPT 94
Query: 105 VHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIV--KASNELCEGQALDLE 162
+HK + AIL GD L ++AF +S A + E K K+++T+ N + GQA+D
Sbjct: 95 LHKSYDETTAILVGDALNTEAFLVLSHAHLKDEIKIKLIKTLAFNAGLNGMVIGQAIDCF 154
Query: 163 FENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWD 222
FE++ + S+ E + + KT L A+ K+G + N E + + G +G+ FQI D
Sbjct: 155 FEDKRL-SLNELEFLHTHKTARLIAAALKMGCEICELNNEESNQIYKLGLKLGLIFQIND 213
Query: 223 DVLDLIADEEKLGKPVGSDIRK 244
D++D+ +E+ GKP +DI K
Sbjct: 214 DIIDVTTSQEQSGKPTNNDIHK 235
>pir||A70139 octaprenyl-diphosphate synthase (ispB) homolog - Lyme disease
spirochete >gi|2688215|gb|AAC66696.1| (AE001138)
octaprenyl-diphosphate synthase (ispB) [Borrelia
burgdorferi]
Length = 347
Score = 120 bits (299), Expect = 2e-26
Identities = 82/291 (28%), Positives = 154/291 (52%), Gaps = 17/291 (5%)
Query: 49 GGKRIRPFVVLTATEAVG--GNALKAIYP-AVAIELIHNYSLVHDDIMDMDETRRGKPTV 105
GGKRIRP +++ A+G K IY ++ +EL H+ SL+ DDI D RRG +
Sbjct: 57 GGKRIRPMIMILLAYALGLKEKNTKLIYKLSLLLELPHSGSLIIDDIEDNSLKRRGASAI 116
Query: 106 HKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFEN 165
H ++GI+ +I AG+L++ + I ++ + +K + E + L GQ +D++F N
Sbjct: 117 HLIYGIDNSINAGNLIYFLPAKLIEKSNLKENQKLLIYENFFTTLSNLHLGQGIDIKFHN 176
Query: 166 REMV-SIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDV 224
+ SI+EY+ ++ KT +LF ++ + I+ T NE+ + + +G+ FQI DD+
Sbjct: 177 ESYIPSIKEYISLVELKTASLFGMASFLAAIL-TNNEDKAKKIYSTFLKLGVYFQIIDDI 235
Query: 225 LDLIADEEKL-GKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGII 283
++ + K+ GK G D+ +GKK+L + +F + ++K + K + F + K
Sbjct: 236 KNI---KNKINGKEFGDDLLEGKKSLPIIYFLQ--EKKFEPKIISKFNQI------KNTK 284
Query: 284 EEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKDL 334
+ E+ + E++ SI ++ +A + + + LN+ P + K+L
Sbjct: 285 TTKARKEIFKLTEMINSSKSIKNSTIVALKYLNEFKNELNLYPLTNRYKNL 335
>gi|9507201 trans-prenyltransferase [Mus musculus]
>gi|4580645|gb|AAD24462.1|AF118855_1 (AF118855)
trans-prenyltransferase [Mus musculus]
Length = 336
Score = 118 bits (293), Expect = 9e-26
Identities = 70/218 (32%), Positives = 114/218 (52%), Gaps = 12/218 (5%)
Query: 38 LYEAARHYPLAGGKRIRPFVVLTATEAVG-----GNALKAIYPAVAI--ELIHNYSLVHD 90
L + + +Y GK RP +V+ A ++A ++A+ E+IH +LVHD
Sbjct: 42 LKDMSEYYFDGKGKAFRPIIVVLMARACNIHHNNAREMQASQRSIALVAEMIHTATLVHD 101
Query: 91 DIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKAS 150
D++D +RRGK TV+K+WG A+LAGDL+ S A A++R V+ + +
Sbjct: 102 DVIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASVALARI-----GNTAVVSMLAQVI 156
Query: 151 NELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRW 210
+L G+ L L + E Y+ KT +L S K ++G + E ++
Sbjct: 157 EDLVRGEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHEIAYQY 216
Query: 211 GRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
G+NVG+AFQ+ DDVLD + +++GKP +D++ G T
Sbjct: 217 GKNVGIAFQLIDDVLDFTSCSDQMGKPTSADLKLGIAT 254
>gb|AAF57135.1| (AE003777) CG3684 gene product [Drosophila melanogaster]
Length = 430
Score = 118 bits (292), Expect = 1e-25
Identities = 84/313 (26%), Positives = 149/313 (46%), Gaps = 33/313 (10%)
Query: 42 ARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYP--------AVAIELIHNYSLVHDDIM 93
A +Y GK +RP V + +A+ + + A+ E++H+ SLVHDD++
Sbjct: 139 ASYYFDGQGKALRPMVTMLMAKAINYHLNNESHQLVHKQRQIALFSEMVHSASLVHDDVI 198
Query: 94 DMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNEL 153
D + RRGKP+V+ +W +AGD + S A +I A + + VL I+ +L
Sbjct: 199 DQSDFRRGKPSVNALWNHKKVTMAGDYILSIA--SIMIARLRSDDVTIVLSQIL---TDL 253
Query: 154 CEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRN 213
+G+ + L E Y+ KT +L + K ++ ++ E ++GRN
Sbjct: 254 VQGEFMQLGSRETENERFAHYLTKTYRKTASLIANALKATAVIAQADDNVAEVAFQYGRN 313
Query: 214 VGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKY 273
+G+AFQ+ DD+LD ++ E++GKP +D++ G T V A EK E V ++
Sbjct: 314 IGLAFQLVDDMLDFVSSTEQMGKPTAADLKLGLATAPVLF----ACEKYPELNPMVMRRF 369
Query: 274 A--GDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRAR 331
+ GDV+ A EL+ + ++ +A++ +A L ES +
Sbjct: 370 SEPGDVE--------------RAFELVHKSHGLEQTRFLAKKHCNEAIRLAQELTESPYQ 415
Query: 332 KDLELLASFMVER 344
K L+++A ++ R
Sbjct: 416 KGLQVVADLVINR 428
>sp|P54976|CRTE_RHOSH GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(FARNESYLTRANSTRANSFERASE) >gi|1075563|pir||S49625
geranylgeranyl pyrophosphate synthase - Rhodobacter
sphaeroides >gi|4490594|emb|CAB38744.1| (AJ010302)
geranylgeranyl pyrophosphate synthase [Rhodobacter
sphaeroides]
Length = 288
Score = 117 bits (291), Expect = 2e-25
Identities = 82/233 (35%), Positives = 116/233 (49%), Gaps = 9/233 (3%)
Query: 35 PKVLYEAARHYPLAGGKRIRPFVVLT-ATEAVGGNALKAIYPAVAIELIHNYSLVHDDIM 93
P L A + GG RIRP ++L+ AT + AVA+ELIH SLVHDD+
Sbjct: 24 PSKLATALDYAVTPGGARIRPTLLLSVATRCGDSRPALSDAAAVALELIHCASLVHDDLP 83
Query: 94 DMD--ETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASN 151
D E RRGKPTVH+ + +AIL GD L FE ++ A ++A L T +
Sbjct: 84 CFDDAEIRRGKPTVHRAYSEPLAILTGDSLIVMGFEVLAGAAADRPQRALQLVTALAVRT 143
Query: 152 ELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWG 211
+ G +E+ +++ Y R KTGALF A+ ++G I E E L G
Sbjct: 144 GMPMGICAGQGWESESQINLSAYHR---AKTGALFIAATQMGAIAAGYEAEPWEEL---G 197
Query: 212 RNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKE 264
+G AFQ+ DD+ D + D E LGKP G D + + + + E A + K+
Sbjct: 198 ARIGEAFQVADDLRDALCDAETLGKPAGQDEIHARPSAVREYGVEGAAKGLKD 250
>gb|AAA91949.1| (L37405) geranylgeranyl pyrophosphate synthase [Streptomyces
griseus] >gi|1632833|emb|CAA64849.1| (X95596) GGPP
synthase [Streptomyces griseus]
Length = 425
Score = 117 bits (291), Expect = 2e-25
Identities = 84/299 (28%), Positives = 144/299 (48%), Gaps = 23/299 (7%)
Query: 45 YPLAGGKRIRPFVVLTATEAVGG-NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKP 103
+ L GGKR+RP ++ + G A+ VA+ELI + +L+HDD+MD RRGKP
Sbjct: 78 FTLEGGKRMRPRLLWWGMRSCGAAETAAALRLGVALELIQSCALIHDDVMDRSRLRRGKP 137
Query: 104 TVH----------------KVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIV 147
+H +G + A+LAGDL A + ++ +S ++ ++
Sbjct: 138 AMHIGLAERAGLSPDSERGSDFGASAAVLAGDLALVWADDTVAETVLSAAQRRRIGALWR 197
Query: 148 KASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL-FDASAKVGGIVGTENEEYIEA 206
E+ GQ LDL + S+ + +R K+ + + +G + ++ +A
Sbjct: 198 AMRTEMVAGQYLDLRGQLSGGSSVAQALRTACLKSASYSVERPLAIGAALAGADDRTTDA 257
Query: 207 LSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKF 266
L GR G+AFQ+ DD+L + D GKP G DIR+GK T ++A +A+ E+
Sbjct: 258 LRSAGRCAGIAFQLRDDLLGVFGDPALTGKPSGDDIREGKSTYLLAVARNSAEASGDEQA 317
Query: 267 LKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID-YASRIARELVEKANEALNV 324
L V G+ G+ + EED+ A+V +E+ ++ A + V + +A++V
Sbjct: 318 LAVLGRATGNA---DLTEEDL-ADVRGVLEVTGARAHVERKAEHLRDHAVRRLGQAVDV 372
>sp|P17060|CRTE_RHOCA GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(FARNESYLTRANSTRANSFERASE) >gi|79512|pir||S04407
phytoene synthase - Rhodobacter capsulatus
>gi|46003|emb|CAA36538.1| (X52291) crtE gene product (AA
1-289) [Rhodobacter capsulatus]
>gi|46128|emb|CAA77545.1| (Z11165) 289 aa (30 kD)
phytoene synthase [Rhodobacter capsulatus]
>gi|227044|prf||1613414G crtE gene [Rhodobacter
capsulatus]
Length = 289
Score = 116 bits (287), Expect = 5e-25
Identities = 79/234 (33%), Positives = 123/234 (51%), Gaps = 19/234 (8%)
Query: 33 KEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAI-YPAVAIELIHNYSLVHDD 91
+ P +L A + GG RIRP ++++ A G + AVA+EL+H SLVHDD
Sbjct: 22 ESPPLLAAALPYGVFPGGARIRPTILVSVALACGDDCPAVTDAAAVALELMHCASLVHDD 81
Query: 92 IMDMD--ETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR-AEISPEKKAKVLETIVK 148
+ D + RRGKP++HK + +A+LAGD L + FE ++ ++P++ K++ + +
Sbjct: 82 LPAFDNADIRRGKPSLHKAYNEPLAVLAGDSLLIRGFEVLADVGAVNPDRALKLISKLGQ 141
Query: 149 ASNE---LCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGI-VGTENEEYI 204
S +C GQA +E+ V + Y + KTGALF A+ ++G I G E E +
Sbjct: 142 LSGARGGICAGQA----WESESKVDLAAYHQ---AKTGALFIAATQMGAIAAGYEAEPWF 194
Query: 205 EALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENA 258
+ G +G AFQI DD+ D + E +GKP G DI + + E A
Sbjct: 195 DL----GMRIGSAFQIADDLKDALMSAEAMGKPAGQDIANERPNAVKTMGIEGA 244
>gb|AAF78199.1|AF218415_1 (AF218415) geranylgeranyl synthase [Bradyrhizobium sp. ORS278]
Length = 316
Score = 115 bits (284), Expect = 1e-24
Identities = 85/242 (35%), Positives = 124/242 (51%), Gaps = 13/242 (5%)
Query: 35 PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMD 94
P L H LAGGKR R +VL +G + + AVAIE IH SLV DD+
Sbjct: 39 PAPLQAGMSHAVLAGGKRYRGMLVLALGSDLGVPEEQLLSSAVAIETIHAASLVVDDLPC 98
Query: 95 MDETRR--GKPTVHKVWGINMAILAGDLLFSKAFEAISR-AEISPEKKAKVLETIVKA-- 149
MD+ RR +P H +G AIL+ L ++A E ++R ++SP ++ +++T+ A
Sbjct: 99 MDDARRRRSQPATHVAFGEATAILSSIALIARAMEVVARDRQLSPASRSSIVDTLSHAIG 158
Query: 150 SNELCEGQALDL--EFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEAL 207
LC GQ DL + E I Y R KT ALF A+ + ++ + E + +
Sbjct: 159 PQALCGGQYDDLYPPYYATEQDLIHRYQR----KTSALFVAAFRCPALLAEVDPETLLRI 214
Query: 208 SRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFL 267
+R G+ +G+AFQI+DD+LDL D +GK VG D G TL A E+A ++
Sbjct: 215 ARAGQRLGVAFQIFDDLLDLTGDAHAIGKDVGQD--HGTVTLATLLGPARAAERAADELA 272
Query: 268 KV 269
V
Sbjct: 273 AV 274
>gi|11499146 octaprenyl-diphosphate synthase (ispB) [Archaeoglobus fulgidus]
>gi|7447581|pir||F69443 octaprenyl-diphosphate synthase
(ispB) homolog - Archaeoglobus fulgidus
>gi|2649009|gb|AAB89695.1| (AE000995)
octaprenyl-diphosphate synthase (ispB) [Archaeoglobus
fulgidus]
Length = 292
Score = 113 bits (279), Expect = 4e-24
Identities = 83/281 (29%), Positives = 140/281 (49%), Gaps = 31/281 (11%)
Query: 17 ERAKLVDEKLFELIPEKEPKVLYEAARHYPL-AGGKRIRPFVVLTATEAVGGNALKAIYP 75
E ++ ++ L + + E + Y + AGGKR RP +VL + + GG+ +
Sbjct: 6 EEYRIFEDSLKKFVESVEATPKIKKGLAYAITAGGKRSRPVIVLLSAKLCGGDYADVMNL 65
Query: 76 AVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEIS 135
A+++ELIH SLVHDD++D E RR + +HK + I++AI+ GD L SK+ E++
Sbjct: 66 ALSVELIHTASLVHDDVIDKAEKRRKREALHKKYDISLAIVLGDWLISKS------VELT 119
Query: 136 PEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGI 195
+ +++ + EG+ LD+ + +E + ++Y I KT ALF SAK
Sbjct: 120 SKYGEEIIRDFSNVGMMMSEGEVLDI-YSIKENFTEKDYFECIEKKTAALFAYSAKSACK 178
Query: 196 VGTENEEYIEALSRWGRNVGMAFQIWDDVLD---LIAD--------------EEKLGKPV 238
+ E+ + L +G N+G+A+QI DD+L+ L+ D EEK GK
Sbjct: 179 IVCEDRIAADKLFDYGLNLGIAYQIVDDLLEYLRLLDDKHSVFESRTLPQIYEEKYGKEE 238
Query: 239 GSDIRKGK------KTLIVAHFFENADEKAKEKFLKVFGKY 273
G + K ++L +F+ + EK K + + F Y
Sbjct: 239 GVNKVMEKISTFVERSLSSLEYFDESPEKEKLRKIVDFMTY 279
>dbj|BAA16579.1| (D90899) prenyltransferase [Synechocystis sp.]
Length = 256
Score = 112 bits (278), Expect = 5e-24
Identities = 78/266 (29%), Positives = 134/266 (50%), Gaps = 23/266 (8%)
Query: 80 ELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
E+IH SLVHDD++D + RR PTV+ ++ +A+LAGD LF+++ ++ +
Sbjct: 11 EMIHTASLVHDDVVDEADLRRNVPTVNSLFDNRVAVLAGDFLFAQSSWYLANLD-----N 65
Query: 140 AKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTE 199
+V++ + + + EG+ L +E Y+ KT +L SAK G++
Sbjct: 66 LEVVKLLSEVIRDFAEGEILQSINRFDTDTDLETYLEKSYFKTASLIANSAKAAGVLSDA 125
Query: 200 NEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENAD 259
+ + L +G+++G+AFQI DD+LD + E LGKP GSD+ G T
Sbjct: 126 PRDVCDHLYEYGKHLGLAFQIVDDILDFTSPTEVLGKPAGSDLISGNITAPALF------ 179
Query: 260 EKAKEKFLKVFGKYAGDVKGKGIIEEDVKA-EVMEAIELLKEHGSIDYASRIARELVEKA 318
A EK+ + GK I E +A ++ +A+EL+++ I + +A + A
Sbjct: 180 --AMEKY---------PLLGKLIEREFAQAGDLEQALELVEQGDGIRRSRELAANQAQLA 228
Query: 319 NEALNVLPESRARKDLELLASFMVER 344
+ L+VL S R+ L L +++ R
Sbjct: 229 RQHLSVLEMSAPRESLLELVDYVLGR 254
>emb|CAC16849.1| (Y17376) geranyl diphosphate synthase [Arabidopsis thaliana]
Length = 422
Score = 112 bits (277), Expect = 7e-24
Identities = 95/336 (28%), Positives = 157/336 (46%), Gaps = 41/336 (12%)
Query: 12 FNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAG--GKRIRPFVVLTATEAVGGNA 69
F+ + + L+ KL E++ + PK L AA ++ G GK+ R ++L A+
Sbjct: 85 FSLVADELSLLSNKLREMVLAEVPK-LASAAEYFFKRGVQGKQFRSTILLLMATALDVRV 143
Query: 70 LKAIYP-----------------AVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGIN 112
+A+ A E+IH SL+HDD++D +TRRG +++ V G
Sbjct: 144 PEALIGESTDIVTSELRVRQRGIAEITEMIHVASLLHDDVLDDADTRRGVGSLNVVMGNK 203
Query: 113 MAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIE 172
M++LAGD L S+A A++ K +V+ + A L G+ +++ + S++
Sbjct: 204 MSVLAGDFLLSRACGALAAL-----KNTEVVALLATAVEHLVTGETMEITSSTEQRYSMD 258
Query: 173 EYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEE 232
YM+ KT +L S K ++ + E +GRN+G+AFQ+ DD+LD
Sbjct: 259 YYMQKTYYKTASLISNSCKAVAVLTGQTAEVAVLAFEYGRNLGLAFQLIDDILDFTGTSA 318
Query: 233 KLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVM 292
LGK SDIR G T + A E+F ++ +V + +E+D + V
Sbjct: 319 SLGKGSLSDIRHGVITAPILF--------AMEEFPQL-----REVVDQ--VEKDPR-NVD 362
Query: 293 EAIELLKEHGSIDYASRIARELVEKANEALNVLPES 328
A+E L + I A +A E A A+ LPE+
Sbjct: 363 IALEYLGKSKGIQRARELAMEHANLAAAAIGSLPET 398
>pir||JC5429 di-trans,poly-cis-decaprenylcistransferase (EC 2.5.1.31)
[similarity] - fission yeast (Schizosaccharomyces pombe)
>gi|1845555|dbj|BAA12314.1| (D84311) decaprenyl
diphosphate synthase [Schizosaccharomyces pombe]
>gi|6714819|emb|CAB66154.1| (AL136498) decaprenyl
diphosphate synthase [Schizosaccharomyces pombe]
Length = 378
Score = 110 bits (272), Expect = 3e-23
Identities = 90/340 (26%), Positives = 158/340 (46%), Gaps = 53/340 (15%)
Query: 38 LYEAARHYPLAGGKRIRPFVVLTATEAVG-------------------------GNALKA 72
L E +++Y +A GK++RP +VL ++A G L +
Sbjct: 59 LEECSKYYTIAQGKQMRPSLVLLMSKATSLCHGIDRSVVGDKYIDDDDLRSFSTGQILPS 118
Query: 73 -IYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
+ A E+IH SL+HDD++D RRG P+ + +G +ILAG+ + ++A A++R
Sbjct: 119 QLRLAQITEMIHIASLLHDDVIDHANVRRGSPSSNVAFGNRRSILAGNFILARASTAMAR 178
Query: 132 AEISPEKKAKVLETIVKASNELCEGQALDLEFE------NREMVSIEEYMRMISGKTGAL 185
+ +V E + +L G+ L L+ + + + Y+ KT +L
Sbjct: 179 L-----RNPQVTELLATVIADLVRGEFLQLKNTMDPSSLEIKQSNFDYYIEKSFLKTASL 233
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
S K I+G + A +GR +G AFQ+ DDVLD + ++ LGK G+D++ G
Sbjct: 234 ISKSCKASTILGQCSPTVATAAGEYGRCIGTAFQLMDDVLDYTSKDDTLGKAAGADLKLG 293
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSID 305
T V A +K E + ++ + +++ A L++ +I+
Sbjct: 294 LATAPVLF----AWKKYPELGAMIVNRF------------NHPSDIQRARSLVECTDAIE 337
Query: 306 YASRIARELVEKANEALNVLPESRARKDLELLASFMVERE 345
A+E ++KA ++L LP+S ARK L LA ++ R+
Sbjct: 338 QTITWAKEYIKKAKDSLLCLPDSPARKALFALADKVITRK 377
>pir||G70935 probable idsA2 protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2911093|emb|CAA17477.1| (AL021957) idsA2
[Mycobacterium tuberculosis]
Length = 352
Score = 110 bits (272), Expect = 3e-23
Identities = 74/237 (31%), Positives = 115/237 (48%), Gaps = 22/237 (9%)
Query: 45 YPLAGGKRIRPFVVLTATEAVGGNALK--AIYPAVAIELIHNYSLVHDDIMDMDETRRGK 102
+ L GGKR+RP AV + A+EL+H ++LVHDD++D TRRG+
Sbjct: 37 FVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWALVHDDLIDRSATRRGR 96
Query: 103 PTVH---------KVW-------GINMAILAGDLLFSKAFEAISR---AEISPEKKAKVL 143
PT + W G++ AIL GDL A + +S+ + ++P+ + +V
Sbjct: 97 PTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVH 156
Query: 144 ETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL-FDASAKVGGIVGTENEE 202
NE+ GQ LD+ E SIE M + + KT ++G + +
Sbjct: 157 RVWADIRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSD 216
Query: 203 YIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENAD 259
+G ++G+AFQ+ DDVL + D GKP G D++ GK+T++VA E AD
Sbjct: 217 VAAIFEHFGADLGVAFQLRDDVLGVFGDPAVTGKPSGDDLKSGKRTVLVAEAVELAD 273
>pir||H70600 probable transferase - Mycobacterium tuberculosis (strain H37RV)
>gi|2052123|emb|CAB08149.1| (Z94752) grcC2
[Mycobacterium tuberculosis]
Length = 325
Score = 109 bits (269), Expect = 6e-23
Identities = 91/304 (29%), Positives = 139/304 (44%), Gaps = 25/304 (8%)
Query: 36 KVLYEAARHYPLAGGKRIRP-FVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMD 94
+V+ + H AGG RP F VL A + + AIEL+H +L HD ++D
Sbjct: 36 EVMRDTVAHLVDAGGTPFRPLFTVLAAQLGSDPDGWEVTVAGAAIELMHLGTLCHDRVVD 95
Query: 95 MDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELC 154
+ R P+ + W N AILAGD F+ A + SR + PE A V E EL
Sbjct: 96 ESDMSRKTPSDNTRWTNNFAILAGDYRFATASQLASR--LDPEAFAVVAEAFA----ELI 149
Query: 155 EGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNV 214
GQ + +IE Y+R++ KTG+L AS ++G + EE I ++R GR +
Sbjct: 150 TGQMRATRGPASHIDTIEHYLRVVHEKTGSLIAASGQLGAALSGAAEEQIRRVARLGRMI 209
Query: 215 GMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFF-ENADEKAKEKFLKVFGKY 273
G AF+I D++ + D L G+D+ + TL + + E + ++ + L
Sbjct: 210 GAAFEISRDIIAISGDSATLS---GADLGQAVHTLPMLYALREQTPDTSRLRELLA---- 262
Query: 274 AGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESRARKD 333
G I +D V EA+ LL+ I A + +A E L LP+ + R+
Sbjct: 263 -------GPIHDD---HVAEALTLLRCSPGIGKAKNVVAAYAAQAREELPYLPDRQPRRA 312
Query: 334 LELL 337
L L
Sbjct: 313 LATL 316
>pir||S32168 dimethylallyltranstransferase (EC 2.5.1.1) - Myxococcus xanthus
>gi|288220|emb|CAA79955.1| (Z21955) geranylgeranyl
pyrophosphate synthetase [Myxococcus xanthus]
Length = 361
Score = 108 bits (268), Expect = 8e-23
Identities = 90/325 (27%), Positives = 151/325 (45%), Gaps = 26/325 (8%)
Query: 25 KLFELIPEKEPKVLYEAA----RHYPLAGGKRIRPFVVLTATEAVGGNAL--KAIYP-AV 77
+LFEL E V + A R Y L KR+RP +V+ G+A+ ++ A
Sbjct: 35 ELFELPDEAGLDVRWTQALTQARAYTLRPAKRLRPALVMAGHCLARGSAVVPSGLWRFAA 94
Query: 78 AIELIHNYSLVHDDIMDMDETRRGKPTVHKVW-----GINMAILAGDLLFSKAFEAISRA 132
+EL+H + L+HDD+ D E RRG P +H++ G ++A++ GD LF++A E + +
Sbjct: 95 GLELLHTFLLIHDDVADQAELRRGAPPLHRMLAPGRAGEDLAVVVGDHLFARALEVMLGS 154
Query: 133 EISPEKKAKVLETIVKASNELCEGQALDLEFENREM--VSIEEYMRMISGKTGAL-FDAS 189
++ A V++ + S GQ LDL+ + V++ + +R+ KT F A
Sbjct: 155 GLTCV--AGVVQYYLGVSGHTAAGQYLDLDLGRAPLAEVTLFQTLRVAHLKTARYGFCAP 212
Query: 190 AKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTL 249
++G + +E L R GR+VG+A+Q+ DD+L L D GK D +GK+T
Sbjct: 213 LVCAAMLGGASSGLVEELERVGRHVGLAYQLRDDLLGLFGDSNVAGKAADGDFLQGKRTF 272
Query: 250 IVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASR 309
V F A E + + ++ +E+ A + A L++ G R
Sbjct: 273 PVLAAFARATEAERTELEALWAL---------PVEQKDAAALARARALVESCGGRAACER 323
Query: 310 IARELVEKANEALNVLPESRARKDL 334
+ A +L LP ++L
Sbjct: 324 MVVRASRAARRSLQSLPNPNGVREL 348
>sp|P21684|CRTE_PANAN GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(FARNESYLTRANSTRANSFERASE) >gi|95607|pir||A37802 crtE
protein - Erwinia uredovora >gi|216682|dbj|BAA14124.1|
(D90087) crtE [Pantoea ananas]
Length = 302
Score = 108 bits (266), Expect = 1e-22
Identities = 86/239 (35%), Positives = 127/239 (52%), Gaps = 18/239 (7%)
Query: 22 VDEKLFELIP-EKEPKVLYEAARHYPLAGGKRIRPFVVLTATE----AVGGNALKAIYPA 76
+D +L +L+P E E V+ A R LA GKRIRP ++L AV + L + A
Sbjct: 23 IDRRLDQLLPVEGERDVVGAAMREGALAPGKRIRPMLLLLTARDLGCAVSHDGLLDL--A 80
Query: 77 VAIELIHNYSLVHDDIMDMDET--RRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE- 133
A+E++H SL+ DD+ MD+ RRG+PT+H +G ++AILA L SKAF I+ A+
Sbjct: 81 CAVEMVHAASLILDDMPCMDDAKLRRGRPTIHSHYGEHVAILAAVALLSKAFGVIADADG 140
Query: 134 ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAK 191
++P K + + + A L +GQ DL E + S E + KT LF AS +
Sbjct: 141 LTPLAKNRAVSELSNAIGMQGLVQGQFKDLS-EGDKPRSAEAILMTNHFKTSTLFCASMQ 199
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLI 250
+ IV + E + L R+ ++G AFQ+ DD+ D + D GK D GK TL+
Sbjct: 200 MASIVANASSEARDCLHRFSLDLGQAFQLLDDLTDGMTD---TGKDSNQD--AGKSTLV 253
>pir||T51127 GGPP synthase [imported] - Brevibacterium linens
>gi|7648574|gb|AAF65590.1|AF139916_11 (AF139916) GGPP
synthase [Brevibacterium linens]
Length = 385
Score = 107 bits (264), Expect = 2e-22
Identities = 69/234 (29%), Positives = 119/234 (50%), Gaps = 21/234 (8%)
Query: 38 LYEAARHYPLAGGKRIRPFVVLTATEAVGG-NALKAIYPAVAIELIHNYSLVHDDIMDMD 96
L+++ H GGK IRP ++L A A+GG + A+ A A++L+H ++HDD++D D
Sbjct: 71 LWDSLTHMA-TGGKLIRPRMLLDAHAALGGRDEHAAVDAACAMQLLHIALVIHDDVIDND 129
Query: 97 ETRRGKPTVH-----------------KVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
RRG+ T+ WGI +IL GDL+ + + ++R +I K+
Sbjct: 130 TIRRGEATISGEFASEAMSRGALRRDANAWGIATSILGGDLILTLSHSLLARLDIEDTKR 189
Query: 140 AKVLETIVKASNELCEGQALDLEFE-NREMVSIEEYMRMISGKTGAL-FDASAKVGGIVG 197
+L+ E G+ D+ + E + + + M+ KT F A + ++
Sbjct: 190 RAILDIFDDTVVESAAGEHSDVWLSLHLEGANSPDVLAMVDQKTAVYSFQAPLLIAAVLA 249
Query: 198 TENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIV 251
+ I+ L+ R +G+ +Q+ DDVL L DE + GK SD+R+GK+TL++
Sbjct: 250 GADSGLIDDLANISRQIGVIYQLRDDVLGLFGDERETGKSNVSDLREGKETLLI 303
>gb|AAB37678.1| (U80443) Similar to hexaprenyl pyrophosphate synthetase; C24A11.9
[Caenorhabditis elegans]
Length = 277
Score = 106 bits (263), Expect = 3e-22
Identities = 74/272 (27%), Positives = 134/272 (49%), Gaps = 26/272 (9%)
Query: 80 ELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
E+IH SLVHDD++D TRRG +V+ VWG M++L GD + ++A + + K
Sbjct: 27 EMIHTASLVHDDVIDEANTRRGSASVNAVWGNKMSVLVGDFILARATQILCSI-----GK 81
Query: 140 AKVLETIVKASNELCEGQALDLEFENREMVSIEE---YMRMISGKTGALFDASAKVGGIV 196
++ + +L G+ + + + ++ Y+ KT +LF +S + I+
Sbjct: 82 PNIISVMASIIEDLVLGEFMQMSTTPTDATPVDRMKAYIEKTHRKTASLFASSCRSAAIL 141
Query: 197 GTENEEYIEALS-RWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFF 255
++ + ++ +GRN+G+AFQ+ DD+LD IA +++GKPV +D++ G T V +
Sbjct: 142 ADGSDLKLHEIAFEYGRNLGIAFQLADDLLDFIATADEMGKPVAADLKLGLATAPVLYAC 201
Query: 256 ENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELV 315
E E L+ F K+ GD + +A E++ +D R+
Sbjct: 202 EQYPE-LNTMLLRKF-KHDGDAE--------------KAREIVVNSDGMDKTRRLIDSYS 245
Query: 316 EKANEALNVLP-ESRARKDLELLASFMVEREY 346
+KA E + LP + + + L LA +R++
Sbjct: 246 QKAVEMASSLPNRNESTEHLIKLAMSQSDRKF 277
>sp|Q45220|ISPA_BRAJA PROBABLE GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE)
(FPP SYNTHASE) >gi|2120793|pir||I40213 probable
dimethylallyltranstransferase (EC 2.5.1.1) -
Bradyrhizobium japonicum >gi|529967|gb|AAC28894.1|
(U12678) putative dimethylallyltranstransferase; ORF6;
similar to E. coli dimethylallyltranstransferase,
Swiss-Prot Accession Number P22939 (Fujisaki et al., J.
Biochem. 108:995-1000(1990) [Bradyrhizobium japonicum]
Length = 332
Score = 104 bits (256), Expect = 2e-21
Identities = 80/244 (32%), Positives = 118/244 (47%), Gaps = 11/244 (4%)
Query: 15 IKERAKLVDEKLFELIPEKEP--KVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKA 72
+++ AK V+E L L+ ++ L A R+ L GGKR R + L A A
Sbjct: 37 MQDGAKRVEEALARLLCAEDDGETELMAAMRYATLHGGKRTRALLCLAAGALADTPAHML 96
Query: 73 IYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAIS 130
AIE++H +LVHDD+ MD D RRG PTVH +G AIL GD L + AF ++
Sbjct: 97 DDVGAAIEMMHACTLVHDDLPAMDDDVLRRGLPTVHVKFGEATAILVGDALQAHAFLTLA 156
Query: 131 RAEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDA 188
+ ++ + +A + GQA+DL + V ++ + M K+GAL A
Sbjct: 157 SLNAPGDSPIALVRELAQAVSAEGAAGGQAIDLSLVGKH-VELDRIVAMHRMKSGALVRA 215
Query: 189 SAKVGGI----VGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRK 244
S ++G + V + AL + G+A Q+ DD+LD+ AD LGK G D
Sbjct: 216 SVRMGALCAVGVNAAHAALYCALDHYSACFGLALQVIDDILDVTADTAALGKTPGKDAAA 275
Query: 245 GKKT 248
K T
Sbjct: 276 QKPT 279
>pir||S52584 crtE protein - Erwinia herbicola >gi|148394|gb|AAA21260.1| (M90698)
crtE protein [Erwinia herbicola]
Length = 302
Score = 102 bits (252), Expect = 6e-21
Identities = 85/239 (35%), Positives = 126/239 (52%), Gaps = 18/239 (7%)
Query: 22 VDEKLFELIP-EKEPKVLYEAARHYPLAGGKRIRPFVVLTATE----AVGGNALKAIYPA 76
+D +L +L+P E E + A R LA GKRIRP ++L AV L I A
Sbjct: 23 IDRRLEQLLPVEGERDFVGAAMREGALAPGKRIRPMLLLLTARDLGCAVSHEGLLDI--A 80
Query: 77 VAIELIHNYSLVHDDIMDMDETR--RGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE- 133
A+E++H SL+ DD+ MD+ + G+PTVH +G ++AILA L SKAF I+ A+
Sbjct: 81 CAVEMVHAASLILDDMPCMDDAQIVGGRPTVHCQYGEHVAILAAVALLSKAFGVIADADG 140
Query: 134 ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAK 191
++ K + + + A L +GQ DL E + S E + KT LF AS +
Sbjct: 141 LTALAKNRAVSELSNAIGMQGLVQGQFKDLS-EGDKRRSAEAILMTNHFKTSTLFCASMQ 199
Query: 192 VGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLI 250
+ IV + E + L R+ ++G AFQ+ DD+ D +AD GK + D +GK TL+
Sbjct: 200 MASIVANASSERRDYLHRFSLDLGQAFQLLDDLTDGMAD---TGKDINQD--EGKSTLV 253
>pir||H64549 octaprenyl-diphosphate synthase - Helicobacter pylori (strain
26695) >gi|2313331|gb|AAD07307.1| (AE000543)
octaprenyl-diphosphate synthase (ispB) [Helicobacter
pylori 26695]
Length = 307
Score = 102 bits (251), Expect = 8e-21
Identities = 81/314 (25%), Positives = 143/314 (44%), Gaps = 52/314 (16%)
Query: 9 DELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGN 68
DELF++I L + + L+ EK +L +
Sbjct: 26 DELFSKIGPSKMLRSKLMLALLNEKTDAILLD---------------------------- 57
Query: 69 ALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEA 128
KA +E+I SL+HDD++D RR P+++ ++G A++ GD+ +SKAF
Sbjct: 58 --KAFNLCAIVEMIQTASLLHDDVIDKAAMRRKLPSINALFGNFNAVMLGDVFYSKAFFE 115
Query: 129 ISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDA 188
+S+ S + +++ A L G+ D+ ++Y R++ KT +A
Sbjct: 116 LSKMGES------IAKSLSNAVLRLSRGEIEDVFVGGSFNSDKQKYWRILEDKTAHFIEA 169
Query: 189 SAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
S K I+ ++ + + +G N GMAFQI DD+LD+ D + LGKP SD ++GK T
Sbjct: 170 SLKSMAILLNKDAKMY---ADFGLNFGMAFQIIDDLLDITQDAKTLGKPNFSDFKEGKTT 226
Query: 249 LIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYAS 308
L +E +++ + + F ++D + E K++G+I+
Sbjct: 227 LPYLLLYEKLNQRDQGLLISYF-------------KQDSHEIIEWTKEKFKQYGTIEETL 273
Query: 309 RIARELVEKANEAL 322
+IA+ +KA EA+
Sbjct: 274 KIAQVYSKKALEAI 287
>pir||D71959 probable octaprenyl-diphosphate synthase - Helicobacter pylori
(strain J99) >gi|4154736|gb|AAD05797.1| (AE001460)
putative OCTAPRENYL-DIPHOSPHATE SYNTHASE [Helicobacter
pylori J99]
Length = 307
Score = 100 bits (247), Expect = 2e-20
Identities = 82/309 (26%), Positives = 144/309 (46%), Gaps = 26/309 (8%)
Query: 16 KERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNAL--KAI 73
++R K + K+ I E E + A + K +R ++L + L KA+
Sbjct: 3 EKRLKAIQNKIASWIKEIESGFI--DALFSKIGPSKMLRSKLMLALLDEKTDAILLDKAL 60
Query: 74 YPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE 133
+E+I SL+HDD++D RR P+++ ++G A++ GD+ +SKAF +S+
Sbjct: 61 NLCAIVEMIQTASLLHDDVIDKATMRRKLPSINALFGNFNAVMLGDVFYSKAFFELSKMG 120
Query: 134 ISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVG 193
S + + + A L G+ D+ ++Y R++ KT +AS K
Sbjct: 121 ES------IAQALSNAVLRLSRGEIEDVFVGECFNSDKQKYWRILEDKTAHFIEASLKSM 174
Query: 194 GIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAH 253
I+ ++ + + +G + GMAFQI DD+LD+ D LGKP SD ++GK TL
Sbjct: 175 AILLNKD---AKMYADFGLHFGMAFQIIDDLLDITQDANTLGKPNFSDFKEGKTTLPYLL 231
Query: 254 FFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARE 313
+E ++ + + F ++D + E K+HG I+ +IA+
Sbjct: 232 LYEKLNQHEQGLLISYF-------------KQDSHEIIEWTKEKFKQHGIIEETLKIAQV 278
Query: 314 LVEKANEAL 322
+KA EA+
Sbjct: 279 YSKKALEAI 287
>sp|P55539|ISPA_RHISN PROBABLE GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE)
(FPP SYNTHASE) >gi|7447859|pir||T10875 y4kU protein -
Rhizobium sp. (strain NGR234) plasmid pNGR234a
>gi|2182498|gb|AAB91752.1| (AE000082) Y4kU [Rhizobium
sp. NGR234]
Length = 332
Score = 100 bits (246), Expect = 3e-20
Identities = 78/240 (32%), Positives = 114/240 (47%), Gaps = 11/240 (4%)
Query: 19 AKLVDEKLFELIPEKE--PKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPA 76
AK V++ L L+ ++ L A R+ L GGKR R + L A A
Sbjct: 41 AKRVEQALARLLCAEDHGETELMAAMRYATLHGGKRTRALLCLAAGALADTPAHILDDVG 100
Query: 77 VAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEI 134
AIE++H +LVHDD+ MD D RRG PTVH +G AIL GD L + AF ++ +
Sbjct: 101 AAIEMMHACTLVHDDLPAMDDDVLRRGLPTVHVKFGEATAILVGDALQAHAFLTLASLDA 160
Query: 135 SPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKV 192
+ + ++ + +A + GQA+DL + V ++ + M K GAL AS ++
Sbjct: 161 PGDNRIALVRELAQAVSAEGAAGGQAMDLSLVGKH-VELDRIVAMHRMKCGALVRASVRM 219
Query: 193 GGIVGTENE----EYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKT 248
G + + AL + G+A Q+ DD+LD AD LGK G D K T
Sbjct: 220 GALCAIAEDAADATLYCALDHYSACFGLALQVVDDILDATADTATLGKTPGKDAAAQKPT 279
>sp|P57537|ISPA_BUCAI GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP
SYNTHASE) >gi|10039128|dbj|BAB13162.1| (AP001119)
geranyltranstransferase [Buchnera sp. APS]
Length = 282
Score = 99.8 bits (245), Expect = 4e-20
Identities = 80/270 (29%), Positives = 138/270 (50%), Gaps = 18/270 (6%)
Query: 11 LFNRIKERAKLVDEKLFELIPEK--EPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGN 68
L+ R K R +++KLF + + + L +A ++ +G KR+R ++ + + N
Sbjct: 6 LYERYKHR---INQKLFYTLNQLPFQKSSLLKAMKYSVFSGSKRLRSSLIYSTGDVFKVN 62
Query: 69 ALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAILAGDLLFSKAF 126
+ AIE IH+YSL+HDD+ MD D RRGK + H +G + ++LAGD L S AF
Sbjct: 63 ITTLDVISTAIEFIHSYSLIHDDLPCMDNDNFRRGKISCHVKYGESTSLLAGDALQSLAF 122
Query: 127 EAISRA---EISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEEYMRMISGK 181
+S + +S K+ K++ + + S+ +C GQ LDLE E ++ V++ E + K
Sbjct: 123 NILSNSFMPNVSNLKRIKMISELSYSIGSSGMCMGQNLDLEAEKKD-VNLSELEIINLYK 181
Query: 182 TGALFDASAKVGGIVGTE-NEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGS 240
T L ++ ++ ++ + L + ++G+AFQI DD+LD D K
Sbjct: 182 TSFLMRSAVRLVYFSSNNFSKSILSILDLFSISIGLAFQIQDDILDFKKDSVKTDNK--K 239
Query: 241 DIRKGKKTLIVAHFFENADEKAKEKFLKVF 270
I+K LI+ + + +K K+ K F
Sbjct: 240 IIKKHTYPLIIG--LDESRKKIKQLHKKSF 267
>emb|CAC16851.1| (AJ243739) geranyl diphosphate synthase [Citrus sinensis]
Length = 321
Score = 99.5 bits (244), Expect = 5e-20
Identities = 84/312 (26%), Positives = 142/312 (44%), Gaps = 44/312 (14%)
Query: 38 LYEAARHYPLAG--GKRIRPFVVLTATEAVGGNALKAIYPAVA----------------- 78
L AA ++ G GKR RP V+L A+ + ++ V
Sbjct: 9 LASAAEYFFKMGVEGKRFRPTVLLLMATALNVRVPEPLHDGVEDASATELRTRQQCIAEI 68
Query: 79 IELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEK 138
E+IH SL+HDD++D +TRRG +++ V G +A+LAGD L S+A A++ K
Sbjct: 69 TEMIHVASLLHDDVLDDADTRRGIGSLNFVMGNKLAVLAGDFLLSRACVALASL-----K 123
Query: 139 KAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGT 198
+V+ + L G+ + + + + S++ YM+ KT +L S K ++
Sbjct: 124 NTEVVTLLATVVEHLVTGETMQMTTSSDQRCSMDYYMQKTYYKTASLISNSCKAIALLAG 183
Query: 199 ENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENA 258
+ E +G+N+G+A+Q+ DDVLD LGK SDIR G T +
Sbjct: 184 QTAEVAILAFDYGKNLGLAYQLIDDVLDFTGTSASLGKGSLSDIRHGIITAPILF----- 238
Query: 259 DEKAKEKFLKVFGKYAGDVKGKGIIEE--DVKAEVMEAIELLKEHGSIDYASRIARELVE 316
A E+F ++ + ++E+ + + V A+E L + I +A +
Sbjct: 239 ---AMEEFPQL----------RTVVEQGFEDSSNVDIALEYLGKSRGIQKTRELAVKHAN 285
Query: 317 KANEALNVLPES 328
A A++ LPE+
Sbjct: 286 LAAAAIDSLPEN 297
>pir||C71295 probable octaprenyl-diphosphate synthase - syphilis spirochete
>gi|2072008|gb|AAB53642.1| (U95214)
octaprenyl-diphosphate synthase [Treponema pallidum]
>gi|3322980|gb|AAC65646.1| (AE001242)
octaprenyl-diphosphate synthase [Treponema pallidum]
Length = 364
Score = 98.3 bits (241), Expect = 1e-19
Identities = 81/309 (26%), Positives = 138/309 (44%), Gaps = 32/309 (10%)
Query: 29 LIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEA-----------VGGNALKAIYP-- 75
++ ++ +VL GGKR RP +++ + E + G+ K I
Sbjct: 35 VLASEDTRVLRTVCNACVSCGGKRWRPLLLILSAELAHACVQCTHRKLQGHKRKKISERE 94
Query: 76 ----AVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
+ +ELIH SL+HDDI D TRRGKP + +G + + A L+ A I
Sbjct: 95 WYTLSAVVELIHTASLLHDDIEDHSSTRRGKPCAYLRYGTDCVLNAASWLYFHAHALIDT 154
Query: 132 AEISPEKKAKVLETIVKASNELCEGQALDLEF-ENREMV-SIEEYMRMISGKTGALFDAS 189
I P KA + + A+ L GQALD+ + + E++ S +Y+RM++ KTGAL S
Sbjct: 155 LSIEPALKAALFSATISATRALHMGQALDIAWHRSPELIPSRAQYLRMVALKTGALIALS 214
Query: 190 AKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTL 249
++G + + + +G+ FQI DDV + D GK DI +GKK+
Sbjct: 215 GELGFLCAGYSAREARSFGAQVMPIGIGFQILDDVQGI--DGGVSGKAHADDIVEGKKSF 272
Query: 250 -IVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYAS 308
++ H + + F + + +G+ VK +A +L ++ +A
Sbjct: 273 PVILHVHTHPQD------APTFARLFAAARAEGLHSPAVK----QAQRILYSSEALTHAR 322
Query: 309 RIARELVEK 317
++E+
Sbjct: 323 AYGLRMIER 331
>dbj|BAA13462.1| (D87817) geranylgeranyl diphosphate synthetase [Thermus
thermophilus]
Length = 344
Score = 96.3 bits (236), Expect = 4e-19
Identities = 78/252 (30%), Positives = 125/252 (48%), Gaps = 17/252 (6%)
Query: 22 VDEKLFELIPEKEPKVLY-EAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIE 80
+ E+L + +P LY + + YP GGK +R + + + A G + A A+E
Sbjct: 12 LQERLIARLDHTDP--LYRDLLQDYPRRGGKMLRGLLTVYSALAHGAPLEAGLETATALE 69
Query: 81 LIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAF----EAISRAEISP 136
L N+ LVHDDI D E RRG+P +H++ + +A+ AGD + ++ + E ++R P
Sbjct: 70 LFQNWVLVHDDIEDGSEERRGRPALHRLHPMPLALNAGDAMHAEMWGLLAEGLARGLFPP 129
Query: 137 EKKAKVLETIVKASNELCEGQALDLEFENREMVSI--EEYMRMISGKTGALFDASAKVGG 194
E + E + + + GQ LDL + + E+Y RM++ K + A +
Sbjct: 130 EVLLEFHEVVRRTAY----GQHLDLLWTLGGTFDLRPEDYFRMVAHKA-VYYTAVVPLRL 184
Query: 195 IVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHF 254
V + A G +G AFQI DDVL+L E GK D+ +GK+TLI+ F
Sbjct: 185 GVLLVGKTPPAAYEEGGLRLGTAFQIVDDVLNLEGGEA-YGKERTGDLYEGKRTLILLRF 243
Query: 255 FENA--DEKAKE 264
E +E+A+E
Sbjct: 244 LEETPPEERARE 255
>sp|P22873|CRTE_ERWHE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(FARNESYLTRANSTRANSFERASE) >gi|95603|pir||C33120
phytoene synthase - Erwinia herbicola
>gi|148400|gb|AAA24819.1| (M38424) phytoene synthase
[Erwinia herbicola] >gi|148408|gb|AAA64977.1| (M87280)
same bases, 40..963, Genbank M38424, function has been
reassigned [Erwinia herbicola]
Length = 307
Score = 95.2 bits (233), Expect = 1e-18
Identities = 87/271 (32%), Positives = 133/271 (48%), Gaps = 18/271 (6%)
Query: 2 KMGVGKYDELFNRIKERAKLVDEKLFELIPEKEPK-VLYEAARHYPLAGGKRIRPFVVLT 60
K GV + E I+ + +D+ L L+PE + + ++ A R +A GKRIRP ++L
Sbjct: 6 KAGVSPHRE----IEVMRQSIDDHLAGLLPETDSQDIVSLAMREGVMAPGKRIRPLLMLL 61
Query: 61 ATEAVG--GNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAIL 116
A + G+ + A A+EL H SL+ DD+ MD E RRG+PT HK +G ++AIL
Sbjct: 62 AARDLRYQGSMPTLLDLACAVELTHTASLMLDDMPCMDNAELRRGQPTTHKKFGESVAIL 121
Query: 117 AGDLLFSKAFEAI-SRAEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEE 173
A L SKAF I + ++ E++A+ + + A L GQ DL + +
Sbjct: 122 ASVGLLSKAFGLIAATGDLPGERRAQAVNELSTAVGVQGLVLGQFRDLNDAALDRTP-DA 180
Query: 174 YMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEK 233
+ KTG LF A ++ I + E L + + G AFQ+ DD+ D D +
Sbjct: 181 ILSTNHLKTGILFSAMLQIVAIASASSPSTRETLHAFALDFGQAFQLLDDLRD---DHPE 237
Query: 234 LGKPVGSDIRKGKKTLIVAHFFENADEKAKE 264
GK D GK TL+ + A +K +E
Sbjct: 238 TGKDRNKD--AGKSTLVNRLGADAARQKLRE 266
>pir||C72242 hypothetical protein TM1535 - Thermotoga maritima (strain MSB8)
>gi|4982102|gb|AAD36602.1|AE001800_12 (AE001800)
octoprenyl-diphosphate synthase, putative [Thermotoga
maritima]
Length = 299
Score = 94.8 bits (232), Expect = 1e-18
Identities = 77/287 (26%), Positives = 144/287 (49%), Gaps = 28/287 (9%)
Query: 2 KMGVGKYDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGK-RIRPFVVLT 60
K+ Y+ ++KER +++ L + PE+ K L PL G R+R ++
Sbjct: 5 KLNQNSYE--LEKVKER---IEQILSQFFPEQIMKDL-------PLYGKMLRVRLSILSF 52
Query: 61 ATEAV--GGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAG 118
V G +A+ ++ A+EL+H SL+HDD++D RRGK T++ ++G A+ AG
Sbjct: 53 KNRGVEIGEDAISSL---AALELVHLASLLHDDVIDGARFRRGKETINFMYGDKAAVAAG 109
Query: 119 DLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMI 178
DL+ AF + EI K + ++ ++ E + ++ + + ++ EEY+R++
Sbjct: 110 DLVLVSAFHTVE--EIGNNKLRRAFLNVI---GKMSEAELIE-QLSRYKPITKEEYLRIV 163
Query: 179 SGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPV 238
GK+GALF + ++ ++ E E L G +G +Q++DD++D A EK+GK
Sbjct: 164 EGKSGALFGLALQLPALL---EGELGEDLYNLGVTIGTIYQMFDDIMD-FAGMEKIGKDG 219
Query: 239 GSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEE 285
D++ G + + E E + + + ++ KGI++E
Sbjct: 220 FLDLKNGVASFPLVTAMEKFPEARQMFENRDWSGLMSFMREKGILKE 266
>pir||T43193 trans-pentaprenyltranstransferase homolog - fission yeast
(Schizosaccharomyces pombe) >gi|1749738|dbj|BAA13926.1|
(D89265) similar to Saccharomyces cerevisiae hexaphenyl
pyrophosphate synthetase precursor, SWISS-PROT Accession
Number p18900 [Schizosaccharomyces pombe]
Length = 356
Score = 94.4 bits (231), Expect = 2e-18
Identities = 75/297 (25%), Positives = 136/297 (45%), Gaps = 40/297 (13%)
Query: 38 LYEAARHYPLAGGKRIRPFVVLTATEAVG-------------------------GNALKA 72
L E +++Y +A GK++RP +VL ++A G L +
Sbjct: 59 LEECSKYYTIAQGKQMRPSLVLLMSKATSLFHGIDRSVVGDKYTDDDDLRSFSTGQILPS 118
Query: 73 -IYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISR 131
+ A E+IH SL+HDD++D RRG P+ + +G +ILAG+ + ++A ++R
Sbjct: 119 QLRLAQITEMIHIASLLHDDVIDHANVRRGSPSSNVAFGNRRSILAGNFILARASTVMAR 178
Query: 132 AEISPEKKAKVLETIVKASNELCEGQALDLEFE------NREMVSIEEYMRMISGKTGAL 185
+ +V E + +L G+ L L+ + + + Y+ KT +L
Sbjct: 179 L-----RNPQVTELLATVIADLVRGEFLQLKNTMDPSSLEIKQSNFDYYIEKSFLKTASL 233
Query: 186 FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKG 245
S K I+G + A +GR +G AFQ+ DDVLD + ++ LGK G+D++ G
Sbjct: 234 ISKSCKASTILGQCSPTVATAAGEYGRCIGTAFQLMDDVLDYTSKDDTLGKAAGADLKLG 293
Query: 246 KKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIE--EDVKAEVMEAIELLKE 300
T V ++ E + F + + + ++E + ++ + AIE +K+
Sbjct: 294 LATAPVLFAWKKYPELG-AMIVNRFNHPSDIQRARSLVECSDAIEQPITWAIEYIKK 349
>pir||C39273 phytoene synthase - Erwinia herbicola
Length = 308
Score = 94.0 bits (230), Expect = 2e-18
Identities = 84/257 (32%), Positives = 127/257 (48%), Gaps = 18/257 (7%)
Query: 2 KMGVGKYDELFNRIKERAKLVDEKLFELIPEKEPK-VLYEAARHYPLAGGKRIRPFVVLT 60
K GV + E I+ + +D+ L L+PE + + ++ A R +A GKRIRP ++L
Sbjct: 6 KAGVSPHRE----IEVMRQSIDDHLAGLLPETDSQDIVSLAMREGVMAPGKRIRPLLMLL 61
Query: 61 ATEAVG--GNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPTVHKVWGINMAIL 116
A + G+ + A A+EL H SL+ DD+ MD E RRG+PT HK +G ++AIL
Sbjct: 62 AARDLRYQGSMPTLLDLACAVELTHTASLMLDDMPCMDNAELRRGQPTTHKKFGESVAIL 121
Query: 117 AGDLLFSKAFEAI-SRAEISPEKKAKVLETIVKA--SNELCEGQALDLEFENREMVSIEE 173
A L SKAF I + ++ E++A+ + + A L GQ DL + +
Sbjct: 122 ASVGLLSKAFGLIAATGDLPGERRAQAVNELSTAVGVQGLVLGQFRDLNDAALDRTP-DA 180
Query: 174 YMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEK 233
+ KTG LF A ++ I + E L + + G AFQ+ DD+ D D +
Sbjct: 181 ILSTNHLKTGILFSAMLQIVAIASASSPSTRETLHAFALDFGQAFQLLDDLRD---DHPE 237
Query: 234 LGKPVGSDIRKGKKTLI 250
GK D GK TL+
Sbjct: 238 TGKDRNKD--AGKSTLV 252
>emb|CAB75644.1| (AL157416) possible geranylgeranyl diphosphate synthase [Leishmania
major]
Length = 742
Score = 92.8 bits (227), Expect = 5e-18
Identities = 92/334 (27%), Positives = 142/334 (41%), Gaps = 39/334 (11%)
Query: 32 EKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDD 91
+K + L+ R GGK R ++++ A+ EL+H SL+ DD
Sbjct: 429 DKICETLFRPVRSIIDRGGKSWRSLILVSCCNALSRQYFDCRRYIAVAELLHVGSLIIDD 488
Query: 92 IMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASN 151
I D RRG VH +G+ AI AG + A ++ PEK +++ +
Sbjct: 489 IQDNSVVRRGGKCVHVEYGVATAINAGSACYFMGPRAARIQDLPPEKASRIYQLYFDVLL 548
Query: 152 ELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDA-----SAKVGGIVGT-------- 198
GQ LD+ + M + E +G LFDA + K GG VG
Sbjct: 549 AGHAGQGLDIYRLDYLMPKVVE-----TGDASTLFDALDAIHTYKTGGAVGALCSMACVL 603
Query: 199 --ENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGK---KTLIVAH 253
EA+ R+G +G+AFQI DD L++ EE L K DI+ GK T I
Sbjct: 604 CEAPTVLSEAVERFGLALGLAFQIVDDALNIRGFEENL-KEEAEDIKDGKITYPTAIAMG 662
Query: 254 FFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARE 313
E AD + L+ K A D++ +A+EL+ + + IAR
Sbjct: 663 RLEAADRQTLWAILRKPTKEAADIQ--------------QAVELIMKVDATSECFLIARH 708
Query: 314 LVEKANEALN-VLPESRARKDLELLASFMVEREY 346
+++ AL+ +L +S + + SF+VER+Y
Sbjct: 709 RLQEMWNALDPLLEDSFPKLLMRTFCSFLVERKY 742
>emb|CAA05825.1| (AJ003049) IspA protein; partial [Wolinella succinogenes]
Length = 163
Score = 88.9 bits (217), Expect = 7e-17
Identities = 56/157 (35%), Positives = 89/157 (56%), Gaps = 9/157 (5%)
Query: 17 ERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIY-P 75
ER + LFE + L+E R+ GGKR RP ++L A+ +K+ Y P
Sbjct: 11 ERFLEEEAPLFEGFHPHYNEYLWEMVRN----GGKRFRPRLLLGVVSALAPLLVKSAYAP 66
Query: 76 AVAIELIHNYSLVHDDIMDMDE--TRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE 133
A+A+E++H YSL+HDD+ MD TRRG PT+H + A+LAGD L + AF +++A
Sbjct: 67 ALALEILHTYSLIHDDLPAMDNAATRRGHPTLHVKYDEASAVLAGDALNTHAFYLLAQAP 126
Query: 134 ISPEKKAKVLETIVKA--SNELCEGQALDLEFENREM 168
+ + K ++ + A + + GQALD FE++++
Sbjct: 127 LGSDTKVALVRELASAGGAGGMVLGQALDCYFEHQKL 163
>pir||E81650 geranylgeranyl pyrophosphate synthase, probable TC0917 [imported] -
Chlamydia muridarum (strain Nigg)
>gi|7190945|gb|AAF39709.1| (AE002358) geranylgeranyl
pyrophosphate synthase, putative [Chlamydia muridarum]
Length = 292
Score = 88.9 bits (217), Expect = 7e-17
Identities = 75/252 (29%), Positives = 114/252 (44%), Gaps = 38/252 (15%)
Query: 47 LAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDI--MDMDETRRGKPT 104
L GGKR+RP +V +++ + A+A+E IH +L+ DD+ MD D+ RRGKP+
Sbjct: 38 LGGGKRVRPLLVCLFADSIQKRR-DVLDTAIAVEYIHTSTLIADDLPCMDNDDMRRGKPS 96
Query: 105 VHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEG--QALDL- 161
VHK + A+LA L A+ I K AK L+ +V E+ + LDL
Sbjct: 97 VHKAFDEASALLASYALIPAAYARI-------RKNAKALKEVVSVQREIEDAYEDVLDLI 149
Query: 162 ------------EFENREMVSI--EEYMRMISGKTGALFDASAKVGGIVGTENEEYIEAL 207
++E+ S E + +I+ KT ALF+ + G + G E +
Sbjct: 150 ELRFGVEGVLGGQYEDVFFQSFTEESVINIINKKTSALFEIACVSGWLFGGGAREKTPLV 209
Query: 208 SRWGRNVGMAFQIWDDVLDLIAD--EEK-------LGKPVGSDI--RKGKKTLIVAHFFE 256
+ RN G+ FQI DD+ DL D EEK G+ D+ R + + H +
Sbjct: 210 IEFARNFGILFQIGDDLADLSQDNQEEKHMNYALLFGEQAAKDLLNRSFNSCIEILHLLK 269
Query: 257 NADEKAKEKFLK 268
K E+ K
Sbjct: 270 EKGVKPLEELCK 281
>emb|CAB94793.1| (AJ133724) geranylgeranyl pyrophosphate synthase [Mycobacterium
aurum]
Length = 371
Score = 87.8 bits (214), Expect = 2e-16
Identities = 77/319 (24%), Positives = 131/319 (40%), Gaps = 32/319 (10%)
Query: 47 LAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVH 106
LA GK +R + + A+ A ++EL+H ++L+ DD+MD RRG+P+ H
Sbjct: 62 LAEGKCVRSTYLYLGWQCGAPADEAALRAAASLELLHAFALLQDDVMDESPMRRGRPSAH 121
Query: 107 KVW----------------GINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKAS 150
+ + G + A+L GDL A + + + + +
Sbjct: 122 RAFERWHRERGLPGSSARFGESAAVLLGDLCLVWAEQMLRESGVDEAALTRAWPRYDAMR 181
Query: 151 NELCEGQALDLEFENREMVSIEEYMRMISGKTGAL-FDASAKVGGIVGTENEEYIEALSR 209
EL GQ DL + ++E + + K+G ++G + + E I L R
Sbjct: 182 TELAVGQFADLVNDTAGFPQLDEVLDVARRKSGNYTVRRPLEIGAALAGCDAEVITVLGR 241
Query: 210 WGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKV 269
+G +G AFQ+ DD+L + + GKP G+D+ K T +V +E A + +F +
Sbjct: 242 YGEAIGEAFQLRDDLLGVFGAPQTTGKPTGTDLVARKATTVVVAGYELATGAQQRQFKEF 301
Query: 270 FGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVLPESR 329
E +V L+ E G++ + A +AL+ L +R
Sbjct: 302 M-----------TAPELSSGDVTRWQALISEVGTVQRIEDMIHRRFAVAVQALDSLDATR 350
Query: 330 ----ARKDLELLASFMVER 344
AR L +AS ER
Sbjct: 351 LDADARSALVAMASACTER 369
>dbj|BAA90525.1| (AB037600) geranylgeranyl diphosphate synthase [Nigrospora
sphaerica]
Length = 392
Score = 85.0 bits (207), Expect = 1e-15
Identities = 81/313 (25%), Positives = 139/313 (43%), Gaps = 37/313 (11%)
Query: 27 FELIPEKEPKVLYEAARHYPLAGGKRIRPFVV--LTATEAVGGNALKAIYPAVAIELIHN 84
F+ E + KV+ + + GK IR ++ A V L+ I AV ++H
Sbjct: 94 FDHWTEAKEKVVTGPYDYIAASPGKEIRSLMLACFNAWLEVPAQRLEVIKRAVG--MLHT 151
Query: 85 YSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLE 144
SL+ DDI D E RRG+P HK++G M I + + ++ A + E++ + V++
Sbjct: 152 ASLLIDDIQDNSELRRGRPVAHKIFGPAMTINSANHMYFLALQ-----ELNALETPGVVD 206
Query: 145 TIVKASNELCEGQALDLEFENREMVSIE-EYMRMISGKTGALFDAS---AKVGGIVGTEN 200
L GQA+DL + E +Y M S KTG LF + K V +
Sbjct: 207 IFTDELLRLHRGQAMDLYWRETLTCPTEADYFEMTSNKTGGLFRLAYRLMKAESAVSVDL 266
Query: 201 EEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADE 260
+E L G+ FQ+ DD +L + E K VG D+ +GK + + H
Sbjct: 267 MPVVELL-------GVLFQVADDYKNLCSREYGDLKGVGEDLTEGKFSFPIIHTIRT--- 316
Query: 261 KAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVME--AIELLKEHGSIDYASRIARELVEKA 318
D++ I+ E + ++ AIEL+++ GS Y + ++L +
Sbjct: 317 ------------NPADLQLLNILRERPTNDHVKRYAIELMEKTGSFRYTRGVLKKLATQV 364
Query: 319 NEALNVLPESRAR 331
+EA++++ + R +
Sbjct: 365 HEAVHLMDQGRGK 377
>sp|P24322|GGPP_NEUCR GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(GGPPSASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE)
[INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
>gi|101846|pir||S15662 farnesyltranstransferase (EC
2.5.1.29) [validated] - Neurospora crassa
>gi|903319|gb|AAC13867.1| (U20940) geranylgeranyl
pyrophosphate synthetase [Neurospora crassa]
Length = 428
Score = 79.6 bits (193), Expect = 5e-14
Identities = 78/306 (25%), Positives = 136/306 (43%), Gaps = 33/306 (10%)
Query: 32 EKEPKVL---YEAARHYPLAGGKRIRPFVV--LTATEAVGGNALKAIYPAVAIELIHNYS 86
E++ KVL Y+ +P GK IR +V A V +L+ I I ++H S
Sbjct: 123 EEKEKVLTGPYDYLNGHP---GKDIRSQMVKAFDAWLDVPSESLEVI--TKVISMLHTAS 177
Query: 87 LVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETI 146
L+ DD+ D RRG P H ++GI I + ++ A + E+ K K +
Sbjct: 178 LLVDDVEDNSVLRRGFPVAHSIFGIPQTINTSNYVYFYALQ-----ELQKLKNPKAVSIF 232
Query: 147 VKASNELCEGQALDLEFENREMVSIE-EYMRMISGKTGALFDASAKVGGIVGTENEEYIE 205
+ L GQ +DL + + E +Y+ M+S KTG LF K ++ E+ ++
Sbjct: 233 SEELLNLHRGQGMDLFWRDTLTCPTEDDYLEMVSNKTGGLFRLGIK---LMQAESRSPVD 289
Query: 206 ALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEK 265
+ +G+ FQI DD +L E K + D+ +GK + V H + + +
Sbjct: 290 CVP-LVNIIGLIFQIADDYHNLWNREYTANKGMCEDLTEGKFSFPVIHSIRS--NPSNMQ 346
Query: 266 FLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKANEALNVL 325
L + + GD E+VK A+ ++ GS +Y ++ + LV++A + +
Sbjct: 347 LLNILKQKTGD--------EEVK---RYAVAYMESTGSFEYTRKVIKVLVDRARQMTEDI 395
Query: 326 PESRAR 331
+ R +
Sbjct: 396 DDGRGK 401
>gb|AAC26705.1| (AC004077) putative trans-prenyltransferase [Arabidopsis thaliana]
Length = 297
Score = 78.8 bits (191), Expect = 8e-14
Identities = 68/249 (27%), Positives = 109/249 (43%), Gaps = 45/249 (18%)
Query: 80 ELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
E+IH SL+HDD++D +TRRG +++ V G
Sbjct: 70 EMIHVASLLHDDVLDDADTRRGVGSLNVVMG----------------------------- 100
Query: 140 AKVLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTE 199
KV+ + A L G+ +++ + S++ YM+ KT +L S K ++ +
Sbjct: 101 NKVVALLATAVEHLVTGETMEITSSTEQRYSMDYYMQKTYYKTASLISNSCKAVAVLTGQ 160
Query: 200 NEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENAD 259
E +GRN+G+AFQ+ DD+LD LGK SDIR G T +
Sbjct: 161 TAEVAVLAFEYGRNLGLAFQLIDDILDFTGTSASLGKGSLSDIRHGVITAPILF------ 214
Query: 260 EKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKAN 319
A E+F ++ +V + +E+D + V A+E L + I A +A E A
Sbjct: 215 --AMEEFPQL-----REVVDQ--VEKDPR-NVDIALEYLGKSKGIQRARELAMEHANLAA 264
Query: 320 EALNVLPES 328
A+ LPE+
Sbjct: 265 AAIGSLPET 273
>sp|Q92236|GGPP_GIBFU GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(GGPPSASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE)
[INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
>gi|1524045|emb|CAA65644.1| (X96943)
Geranylgeranylpyrophosphate Synthetase [Gibberella
fujikuroi]
Length = 418
Score = 76.1 bits (184), Expect = 6e-13
Identities = 59/254 (23%), Positives = 113/254 (44%), Gaps = 25/254 (9%)
Query: 79 IELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEK 138
+ ++H SL+ DD+ D E RRG P H ++G+ I +G+ ++ A + + + +PE
Sbjct: 171 VGMLHESSLLIDDVQDSSELRRGFPVAHNIFGVAQTINSGNYIYFVALQELHKLN-NPEL 229
Query: 139 KAKVLETIVKASNELCEGQALDLEF-ENREMVSIEEYMRMISGKTGALFDASAKV--GGI 195
+ +V L GQ +DL + + + E+Y+ M+ KTG LF K+
Sbjct: 230 ITIFSDELV----NLHRGQGMDLFWCDTLTCPTEEDYLEMVGNKTGGLFRLGIKLMAAEA 285
Query: 196 VGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFF 255
G + + ++ +G+ FQI DD ++L + E K + D+ +GK + V H
Sbjct: 286 NGPSPTDCVPLVNL----IGLIFQIRDDYMNLSSKEYSHNKGMCEDLTEGKFSFPVIHSI 341
Query: 256 ENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELV 315
+ + + + D + K A+ ++ GS +Y ++ L+
Sbjct: 342 RT--NPTNLQLINILKQKTSDTQIK-----------RYAVAYMESTGSFEYTRKVLSVLI 388
Query: 316 EKANEALNVLPESR 329
E+A + L + R
Sbjct: 389 ERARKMAEELDQGR 402
>gb|AAC05273.1| (AF049659) geranylgeranyl pyrophosphate synthase [Drosophila
melanogaster]
Length = 338
Score = 73.7 bits (178), Expect = 3e-12
Identities = 75/306 (24%), Positives = 131/306 (42%), Gaps = 28/306 (9%)
Query: 17 ERAKLVDEKLFELIPEKEP-KVLYEAARHYPLAGGKRIRPFVVLTATE--AVGGNALKAI 73
E ++ +K + +KE ++L + + GK+ R + L + G L I
Sbjct: 2 EELNIILQKTKDKSTQKEQDEILLQPFTYIQQIPGKQFRSELALAFNHWLLIPGEKLAQI 61
Query: 74 YPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE 133
V +++HN SL+ DDI D RRG P H ++G+ I A + A E + + +
Sbjct: 62 GDIV--QMLHNSSLLIDDIEDNSILRRGVPVAHSIYGVASTINAANYALFLALEKVQQLD 119
Query: 134 ISPEKKAKVLETIVKASNELCEGQALDLEF-ENREMVSIEEYMRMISGKTGALFDASAKV 192
PE E ++ EL GQ +++ + ++ S +Y M KTG LF + ++
Sbjct: 120 -HPEATKVYTEQLL----ELHRGQGMEIYWRDSFTCPSESDYKLMTVRKTGGLFMLAIRL 174
Query: 193 GGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVA 252
+ + E+Y S+ +G+ FQI DD +L E K D+ +GK V
Sbjct: 175 MQLFSSNKEDY----SKLTAILGLYFQIRDDYCNLSLKEYTENKSFAEDLTEGKFGFPVI 230
Query: 253 HFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIAR 312
H +K ++ L + + D++ K I LL++ GS Y ++
Sbjct: 231 HAVRT--QKQDKQVLHILRQRTHDIEVK-----------KYCITLLEKLGSFQYTRKVLE 277
Query: 313 ELVEKA 318
L +A
Sbjct: 278 SLDAEA 283
>gb|AAF50574.1| (AE003559) qm gene product [Drosophila melanogaster]
Length = 338
Score = 73.7 bits (178), Expect = 3e-12
Identities = 75/306 (24%), Positives = 131/306 (42%), Gaps = 28/306 (9%)
Query: 17 ERAKLVDEKLFELIPEKEP-KVLYEAARHYPLAGGKRIRPFVVLTATE--AVGGNALKAI 73
E ++ +K + +KE ++L + + GK+ R + L + G L I
Sbjct: 2 EELNIILQKTKDKSTQKEQDEILLQPFTYIQQIPGKQFRSELALAFNHWLLIPGEKLAQI 61
Query: 74 YPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE 133
V +++HN SL+ DDI D RRG P H ++G+ I A + A E + + +
Sbjct: 62 GDIV--QMLHNSSLLIDDIEDNSILRRGVPVAHSIYGVASTINAANYALFLALEKVQQLD 119
Query: 134 ISPEKKAKVLETIVKASNELCEGQALDLEF-ENREMVSIEEYMRMISGKTGALFDASAKV 192
PE E ++ EL GQ +++ + ++ S +Y M KTG LF + ++
Sbjct: 120 -HPEATKVYTEQLL----ELHRGQGMEIYWRDSFTCPSESDYKLMTVRKTGGLFMLAIRL 174
Query: 193 GGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVA 252
+ + E+Y S+ +G+ FQI DD +L E K D+ +GK V
Sbjct: 175 MQLFSSNKEDY----SKLTAILGLYFQIRDDYCNLSLKEYTENKSFAEDLTEGKFGFPVI 230
Query: 253 HFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIAR 312
H +K ++ L + + D++ K I LL++ GS Y ++
Sbjct: 231 HAVRT--QKQDKQVLHILRQRTHDIEVK-----------KYCITLLEKLGSFQYTRKVLE 277
Query: 313 ELVEKA 318
L +A
Sbjct: 278 SLDAEA 283
>emb|CAB57417.1| (AL121746) putative polyprenyl synthetase [Streptomyces coelicolor
A3(2)]
Length = 352
Score = 73.4 bits (177), Expect = 4e-12
Identities = 73/313 (23%), Positives = 130/313 (41%), Gaps = 36/313 (11%)
Query: 38 LYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVA-IELIHNYSLVHDDIMDMD 96
L +AA H GKR+R A G A+ A A +EL+H ++VHDD++D
Sbjct: 43 LRKAAGH-----GKRLRAAFCYWGWRAAGQPESDALVRAAASMELVHAAAVVHDDLIDDS 97
Query: 97 ETRRGKPTVH---------------KVWGINMAILAGDLLFSKAFEAISRAEISPEKKAK 141
R G PT H + ++A+L GD L A + + + A+
Sbjct: 98 RLRHGLPTAHVALEAVLARDGRPDARTAARSLAMLVGDQLMVLAGLLFTTSGLPAAYLAR 157
Query: 142 VLETIVKASNELCEGQALDLEFENREMVSIEEYMRMISGKTGAL-FDASAKVGGIVGTEN 200
+ + EL G+ L++ ++++ KT + +GG++
Sbjct: 158 ARDLWAVLARELVAGECLEI-LHTGGPPDTGTSLKVVRYKTAKYTVEHPLLIGGLLAGAA 216
Query: 201 EEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADE 260
+ + +G AFQ+ DD+L L D E+ GK D+R + T ++A ++ AD
Sbjct: 217 PALRDTYRAYALPLGEAFQLRDDLLGLFGDPERTGKASLDDLRAHRPTALLAETWKAADA 276
Query: 261 KAKEKFLKVFGK------YAGDVK-------GKGIIEEDVKAEVMEAIELLKEHGSIDYA 307
++ ++ G+ + DV+ +E+ + V A L G+ +A
Sbjct: 277 SQRQWLRRLLGRDDLDATHLHDVRRLMRELNAPQRVEQMIADRVERATRALDGAGTPPHA 336
Query: 308 SRIARELVEKANE 320
R REL ++A +
Sbjct: 337 RRALRELAQQATD 349
>gi|6325188 geranylgeranyl diphosphate synthase; Bts1p [Saccharomyces
cerevisiae] >gi|2131253|pir||S60921
farnesyltranstransferase (EC 2.5.1.29) - yeast
(Saccharomyces cerevisiae) >gi|1079673|gb|AAB68296.1|
(U39205) Lpe1p [Saccharomyces cerevisiae]
>gi|1098641|gb|AAA83262.1| (U31632) Bts1p [Saccharomyces
cerevisiae]
Length = 335
Score = 73.0 bits (176), Expect = 5e-12
Identities = 66/299 (22%), Positives = 131/299 (43%), Gaps = 20/299 (6%)
Query: 44 HYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKP 103
H L GK R +++ + + + +EL+HN SL+ DDI D RRG+
Sbjct: 29 HILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQT 88
Query: 104 TVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEF 163
T H ++G+ I + ++ +A + +S+ ++ + L GQ LD+ +
Sbjct: 89 TSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYW 148
Query: 164 EN--REMVSIEE-YMRMISGKTGALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQI 220
+ E++ +E Y+ M+ KTG LF + ++ + + + + +L + +G+ +QI
Sbjct: 149 RDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEAL-SPSSHHGHSLVPFINLLGIIYQI 207
Query: 221 WDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAK----EKFLKVFGKYAGD 276
DD L+L + K DI +GK + + H K + + L++ D
Sbjct: 208 RDDYLNLKDFQMSSEKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSD 267
Query: 277 VKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVE--KANEALNVLPESRARKD 333
+D+K ++++ +E + S+ Y +LV K + LP+ + D
Sbjct: 268 --------KDIKLKLIQILEF--DTNSLAYTKNFINQLVNMIKNDNENKYLPDLASHSD 316
>gi|4758430 geranylgeranyl diphosphate synthase 1 [Homo sapiens]
>gi|6831549|sp|O95749|GGPP_HUMAN GERANYLGERANYL
PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE) (GGPPSASE)
(GERANYLGERANYL DIPHOSPHATE SYNTHASE) [INCLUDES:
DIMETHYLALLYLTRANSFERASE ; GERANYLTRANSTRANSFERASE ;
FARNESYLTRANSTRANSFERASE ] >gi|4520350|dbj|BAA75909.1|
(AB017971) geranylgeranyl diphosphate synthase [Homo
sapiens] >gi|4586866|dbj|BAA76511.1| (AB016043) GGPP
synthase [Homo sapiens] >gi|4730813|dbj|BAA77251.1|
(AB019036) geranylgeranyl pyrophosphate synthase [Homo
sapiens] >gi|5410359|gb|AAD43050.1|AF125394_1 (AF125394)
gerannylgeranyl pyrophosphate synthase [Homo sapiens]
Length = 300
Score = 73.0 bits (176), Expect = 5e-12
Identities = 61/245 (24%), Positives = 108/245 (43%), Gaps = 23/245 (9%)
Query: 80 ELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
E++HN SL+ DDI D + RRG P H ++GI I + + ++ E + +
Sbjct: 54 EMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLD-----H 108
Query: 140 AKVLETIVKASNELCEGQALDLEF-ENREMVSIEEYMRMISGKTGALFDASAKVGGIVGT 198
++ + EL +GQ LD+ + +N + EEY M+ KTG LF + + +
Sbjct: 109 PDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLF-- 166
Query: 199 ENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENA 258
+Y E L +G+ FQI DD +L + E K D+ +GK + H +
Sbjct: 167 --SDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSR 224
Query: 259 DEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKA 318
E + + ++ + D+K + L++ GS +Y +EL KA
Sbjct: 225 PESTQVQ----------NILRQRTENIDIK---KYCVHYLEDVGSFEYTRNTLKELEAKA 271
Query: 319 NEALN 323
+ ++
Sbjct: 272 YKQID 276
>gi|11422894 geranylgeranyl diphosphate synthase 1 [Homo sapiens]
Length = 293
Score = 73.0 bits (176), Expect = 5e-12
Identities = 61/245 (24%), Positives = 108/245 (43%), Gaps = 23/245 (9%)
Query: 80 ELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
E++HN SL+ DDI D + RRG P H ++GI I + + ++ E + +
Sbjct: 47 EMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLD-----H 101
Query: 140 AKVLETIVKASNELCEGQALDLEF-ENREMVSIEEYMRMISGKTGALFDASAKVGGIVGT 198
++ + EL +GQ LD+ + +N + EEY M+ KTG LF + + +
Sbjct: 102 PDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLF-- 159
Query: 199 ENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENA 258
+Y E L +G+ FQI DD +L + E K D+ +GK + H +
Sbjct: 160 --SDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSR 217
Query: 259 DEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKA 318
E + + ++ + D+K + L++ GS +Y +EL KA
Sbjct: 218 PESTQVQ----------NILRQRTENIDIK---KYCVHYLEDVGSFEYTRNTLKELEAKA 264
Query: 319 NEALN 323
+ ++
Sbjct: 265 YKQID 269
>gi|6806915 geranylgeranyl diphosphate synthase 1; GGPP synthase [Mus musculus]
>gi|6831551|sp|Q9WTN0|GGPP_MOUSE GERANYLGERANYL
PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE) (GGPPSASE)
(GERANYLGERANYL DIPHOSPHATE SYNTHASE) [INCLUDES:
DIMETHYLALLYLTRANSFERASE ; GERANYLTRANSTRANSFERASE ;
FARNESYLTRANSTRANSFERASE ] >gi|4586868|dbj|BAA76512.1|
(AB016044) GGPP synthase [Mus musculus]
Length = 300
Score = 72.6 bits (175), Expect = 6e-12
Identities = 70/292 (23%), Positives = 121/292 (40%), Gaps = 23/292 (7%)
Query: 28 ELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGGNALKAIYPAVAIELIHNYSL 87
E EK ++L E R+ GK++R + + K E++HN SL
Sbjct: 2 EKTKEKAERILLEPYRYLLQLPGKQVRSKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASL 61
Query: 88 VHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKKAKVLETIV 147
+ DDI D + RRG P H ++G+ I + + ++ E + + ++
Sbjct: 62 LIDDIEDSSKLRRGFPVAHSIYGVPSVINSANYVYFLGLEKVLTLD-----HPDAVKLFT 116
Query: 148 KASNELCEGQALDLEF-ENREMVSIEEYMRMISGKTGALFDASAKVGGIVGTENEEYIEA 206
+ EL +GQ LD+ + + + EEY M+ KTG LF + + + +Y E
Sbjct: 117 RQLLELHQGQGLDIYWRDTYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLF----SDYKED 172
Query: 207 LSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAKEKF 266
L +G+ FQI DD +L + E K D+ +GK + H + E + +
Sbjct: 173 LKPLLDTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQ- 231
Query: 267 LKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKA 318
++ + D+K ++ L++ GS Y REL KA
Sbjct: 232 ---------NILRQRTENIDIK---KYCVQYLEDVGSFAYTRHTLRELEAKA 271
>emb|CAA08919.1| (AJ009963) farnesyl pyrophosphate synthase [Drosophila
melanogaster]
Length = 380
Score = 71.0 bits (171), Expect = 2e-11
Identities = 62/240 (25%), Positives = 107/240 (43%), Gaps = 19/240 (7%)
Query: 68 NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
N A Y +E++ ++ ++ DD+MD TRRG+P HKV + + + L+ A
Sbjct: 111 NIKLAQYLGWCVEMLQSFFIISDDVMDNSTTRRGQPCWHKVENVGLTAINDALMIENAMY 170
Query: 128 AISRAEISP-EKKAKVLETIVKASNELCEGQALDLEFENR--EMVSIEEYMRMISGKTG- 183
AI + S + ++E + + GQ+LD NR ++E Y ++ KT
Sbjct: 171 AILKKHFSHLDCYVALMELFHEITYITTCGQSLDQLNSNRCVSEFTMENYKAIVENKTAY 230
Query: 184 -ALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDI 242
+ + A + G ++ E +G FQ+ DD LD + E GK +G+DI
Sbjct: 231 YSFYLPFALALHLAGYKDAEAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGK-IGTDI 289
Query: 243 RKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHG 302
+ K + + + A+ + K+ + +GK EE K E ++ EL KE G
Sbjct: 290 QDNKCSWLAVVAMQRANVEQKQIMVDCYGK-----------EEPAKVERVK--ELYKELG 336
>gb|AAD27853.1|AF132554_1 (AF132554) farnesyl pyrophosphate synthase [Drosophila
melanogaster] >gi|7303618|gb|AAF58670.1| (AE003826) Fpps
gene product [Drosophila melanogaster]
Length = 419
Score = 71.0 bits (171), Expect = 2e-11
Identities = 62/240 (25%), Positives = 107/240 (43%), Gaps = 19/240 (7%)
Query: 68 NALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFE 127
N A Y +E++ ++ ++ DD+MD TRRG+P HKV + + + L+ A
Sbjct: 150 NIKLAQYLGWCVEMLQSFFIISDDVMDNSTTRRGQPCWHKVENVGLTAINDALMIENAMY 209
Query: 128 AISRAEISP-EKKAKVLETIVKASNELCEGQALDLEFENR--EMVSIEEYMRMISGKTG- 183
AI + S + ++E + + GQ+LD NR ++E Y ++ KT
Sbjct: 210 AILKKHFSHLDCYVALMELFHEITYITTCGQSLDQLNSNRCVSEFTMENYKAIVENKTAY 269
Query: 184 -ALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDI 242
+ + A + G ++ E +G FQ+ DD LD + E GK +G+DI
Sbjct: 270 YSFYLPFALALHLAGYKDAEAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGK-IGTDI 328
Query: 243 RKGKKTLIVAHFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHG 302
+ K + + + A+ + K+ + +GK EE K E ++ EL KE G
Sbjct: 329 QDNKCSWLAVVAMQRANVEQKQIMVDCYGK-----------EEPAKVERVK--ELYKELG 375
>sp|P56966|GGPP_BOVIN GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (GGPP SYNTHETASE)
(GGPPSASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE)
[INCLUDES: DIMETHYLALLYLTRANSFERASE ;
GERANYLTRANSTRANSFERASE ; FARNESYLTRANSTRANSFERASE ]
Length = 294
Score = 71.0 bits (171), Expect = 2e-11
Identities = 61/245 (24%), Positives = 107/245 (42%), Gaps = 23/245 (9%)
Query: 80 ELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAEISPEKK 139
E++HN SL+ DDI D + RRG P H ++GI I + + ++ E ++
Sbjct: 52 EMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLE-----KVLTLNH 106
Query: 140 AKVLETIVKASNELCEGQALDLEF-ENREMVSIEEYMRMISGKTGALFDASAKVGGIVGT 198
++ + EL +GQ LD+ + +N + EEY M+ KTG LF + + +
Sbjct: 107 PDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLF-- 164
Query: 199 ENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENA 258
+Y E L +G+ FQI DD +L + E K D+ +GK + H +
Sbjct: 165 --SDYKEDLKPLLDTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSR 222
Query: 259 DEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIARELVEKA 318
E + + ++ + D+K + L+ GS +Y +EL KA
Sbjct: 223 PESTQVQ----------NILRQRTENIDIK---KYCVHYLENVGSFEYTRNTLKELESKA 269
Query: 319 NEALN 323
+ ++
Sbjct: 270 YKQID 274
>pir||T06272 farnesyl-pyrophosphate synthetase FPS1 - tomato
>gi|2935459|gb|AAC73051.1| (AF048747) farnesyl
pyrophosphate synthase [Lycopersicon esculentum]
Length = 342
Score = 70.6 bits (170), Expect = 2e-11
Identities = 71/270 (26%), Positives = 126/270 (46%), Gaps = 19/270 (7%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAV-GGNALKA--IY 74
++ L+++ FE + V + Y + GGK R V+ + + G L A I+
Sbjct: 16 KSDLLEDTAFEFTDDSRKWV--DKMLDYNVPGGKLNRGLSVIDSLSLLKDGKELTADEIF 73
Query: 75 PAVA----IELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAIS 130
A A IE + Y LV DDIMD TRRG+P + + + M + +L I
Sbjct: 74 KASALGWCIEWLQAYFLVLDDIMDGSHTRRGQPCWYNLEKVGMIAINDGILLRNHITRIL 133
Query: 131 RAEISPEK-KAKVLETIVKASNELCEGQALDL-----EFENREMVSIEEYMRMISGKTG- 183
+ PE +L+ + + GQ +DL ++ S+ + R++ KT
Sbjct: 134 KKYFRPESYYVDLLDLFNEVEFQTASGQMIDLITTLVGEKDLSKYSLSIHRRIVQYKTAY 193
Query: 184 -ALFDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDI 242
+ + A +VG +++++ + + ++G+ FQ+ DD LD AD E LGK +G+DI
Sbjct: 194 YSFYLPVACALLMVGENLDKHVD-VKKILIDMGIYFQVQDDYLDCFADPEVLGK-IGTDI 251
Query: 243 RKGKKTLIVAHFFENADEKAKEKFLKVFGK 272
+ K + +V E +E+ K+ + +GK
Sbjct: 252 QDFKCSWLVVKALELCNEEQKKILFENYGK 281
>emb|CAA59170.1| (X84695) dimethylallyltransferase [Capsicum annuum]
Length = 342
Score = 69.9 bits (168), Expect = 4e-11
Identities = 69/269 (25%), Positives = 116/269 (42%), Gaps = 17/269 (6%)
Query: 18 RAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTA-------TEAVGGNAL 70
+++L+++ FE + V + Y + GGK R V+ + E
Sbjct: 16 KSELLNDPGFEFTDDSREWV--DKMLEYNVPGGKLNRGLSVIDSYSLVDDGKELTRDEIF 73
Query: 71 KAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAIS 130
KA IE + Y LV DDIMD TRRG+P +KV + M + +L I
Sbjct: 74 KASALGWCIEWLQAYFLVLDDIMDNSHTRRGQPCWYKVEKVGMIAVNDGILLRNHISRIL 133
Query: 131 RAEISPEK-KAKVLETIVKASNELCEGQALDL-----EFENREMVSIEEYMRMISGKTGA 184
+ P+ +L+ + + GQ +DL ++ S+ + R++ KT
Sbjct: 134 KNHFRPKSYYVDLLDLFNEVEFQTASGQMIDLITTHVGEKDLSKYSLPIHCRIVQYKTAY 193
Query: 185 L-FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIR 243
F ++ EN + + +G+ FQ+ DD LD AD E LGK +G+DI+
Sbjct: 194 YSFYLPVACALLMAGENLDNHVDVKNILIEMGIYFQVQDDYLDCFADPEVLGK-IGTDIQ 252
Query: 244 KGKKTLIVAHFFENADEKAKEKFLKVFGK 272
K + +V E +E+ K+ + +GK
Sbjct: 253 DFKCSWLVVKALELCNEEQKKILYENYGK 281
>pir||T23962 hypothetical protein R06C1.2 - Caenorhabditis elegans
>gi|5824560|emb|CAB03221.2| (Z81106) predicted using
Genefinder~contains similarity to Pfam domain: PF00348
(Polyprenyl synthetases), Score=132.0, E-value=3.5e-36,
N=1~cDNA EST yk573d7.3 comes from this gene~cDNA EST
yk573d7.5 comes from this gene [Caenorhabditis elegans]
Length = 352
Score = 69.5 bits (167), Expect = 5e-11
Identities = 62/237 (26%), Positives = 108/237 (45%), Gaps = 10/237 (4%)
Query: 70 LKAIYPAVA-IELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEA 128
L+A+ A A +E+I ++ L+ DDIMD ETRRGKP + G+ M+ + + E
Sbjct: 78 LQAVCEAAATLEIIQSFYLIADDIMDNSETRRGKPCWFRREGVGMSAINDAFIMDSFVED 137
Query: 129 ISRAEISPEKKA-KVLETIVKASNELCEGQALDLEFENR-EMVSIEEYMRMISGKTGALF 186
I R + ++ E K+ + GQ LD N+ + + Y M+ KT
Sbjct: 138 ILRLALPGHVNLDRLCEAYRKSKQKTLIGQFLDTSSVNQISSFTWDRYELMVENKTSHYT 197
Query: 187 DASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGK 246
++ ++ Y ++ + +G FQ DD LD+ D + GK +G+DI+ GK
Sbjct: 198 VFHPIQMALIISDVLAYHGSVKKVAYQIGFLFQSQDDFLDVYGDPKITGK-IGTDIQDGK 256
Query: 247 KTLIVAHFFE---NADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKE 300
T + + EK K ++ F G V + + E +K + + ++L +E
Sbjct: 257 CTWLAVRALQKMHKTPEKWGAKLIEEFKTSFGSVDPEKV--EKIK-RIYDELQLKQE 310
>pir||PV0010 hypothetical protein 131 (nlp 5' region) - Escherichia coli
(fragment) >gi|388220|emb|CAA48735.1| (X68873) OrfX in
[1] [Escherichia coli]
Length = 131
Score = 69.1 bits (166), Expect = 7e-11
Identities = 47/143 (32%), Positives = 74/143 (50%), Gaps = 14/143 (9%)
Query: 204 IEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVAHFFENADEKAK 263
I L +GR +G AFQ+ DD+LD AD E+LGK VG D+ +GK TL + H + +
Sbjct: 1 IPDLQDYGRYLGTAFQLIDDLLDYNADGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQA 60
Query: 264 EKFLKVFGKYAGDVKGKGIIEEDVKAEVME-AIELLKEHGSIDYASRIARELVEKANEAL 322
+ + IE+ ++E +E + GS+++ + A E +KA AL
Sbjct: 61 QMI-------------RTAIEQGNGRHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAAL 107
Query: 323 NVLPESRARKDLELLASFMVERE 345
VLP++ R+ L LA V+R+
Sbjct: 108 QVLPDTPWREALIGLAHIAVQRD 130
>pir||T03687 farnesyl-pyrophosphate synthetase - rice
>gi|2073375|dbj|BAA19856.1| (D85317) farnesyl
pyrophosphate synthase [Oryza sativa]
>gi|4063829|dbj|BAA36276.1| (AB021747) farnesyl
diphosphate synthase [Oryza sativa]
Length = 353
Score = 68.7 bits (165), Expect = 9e-11
Identities = 70/279 (25%), Positives = 120/279 (42%), Gaps = 19/279 (6%)
Query: 8 YDELFNRIKERAKLVDEKLFELIPEKEPKVLYEAARHYPLAGGKRIRPFVVLTATEAVGG 67
+ E+++R+KE +++++ FE E + + Y + GGK R V+ + + + G
Sbjct: 19 FAEIYSRLKE--EMLEDPAFEFTDESLQWI--DRMLDYNVLGGKCNRGISVIDSFKMLKG 74
Query: 68 N-------ALKAIYPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINM-AILAGD 119
A IE + Y LV DDIMD +TRRG+P +V + + A+ G
Sbjct: 75 TDVLNKEETFLACTLGWCIEWLQAYFLVLDDIMDNSQTRRGQPCWFRVPQVGLIAVNDGI 134
Query: 120 LLFSKAFEAISRAEISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIEEY----- 174
+L + + R +++ + + GQ LDL + + +Y
Sbjct: 135 ILRNHISRILQRHFKGKLYYVDLIDLFNEVEFKTASGQLLDLITTHEGEKDLTKYNLTVH 194
Query: 175 MRMISGKTGAL-FDASAKVGGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEK 233
R++ KT F ++ EN + + +G FQ+ DD LD D E
Sbjct: 195 RRIVQYKTAYYSFYLPVACALLLSGENLDNFGDVKNILVEMGTYFQVQDDYLDCYGDPEF 254
Query: 234 LGKPVGSDIRKGKKTLIVAHFFENADEKAKEKFLKVFGK 272
+GK +G+DI K + +V E ADE K + +GK
Sbjct: 255 IGK-IGTDIEDYKCSWLVVQALERADENQKHILFENYGK 292
>gb|AAC05595.1| (AF049658) geranylgeranyl pyrophosphate synthase [Drosophila
melanogaster]
Length = 335
Score = 68.7 bits (165), Expect = 9e-11
Identities = 73/313 (23%), Positives = 133/313 (42%), Gaps = 31/313 (9%)
Query: 17 ERAKLVDEKLFELIPEKEP-KVLYEAARHYPLAGGKRIRPFVVLTATE--AVGGNALKAI 73
E ++ +K + +KE ++L + + GK+ R + L + G L I
Sbjct: 2 EELNIILQKTKDKSTQKEQDEILLQPFTYIQQIPGKQFRSELALAFNHWLLIPGEKLAQI 61
Query: 74 YPAVAIELIHNYSLVHDDIMDMDETRRGKPTVHKVWGINMAILAGDLLFSKAFEAISRAE 133
++++HN SL+ I D RRG P H ++G+ I A + A E + + +
Sbjct: 62 --GNIVQMLHNSSLL---IEDNSILRRGVPVAHSIYGVASTINAANYALFLALEKVQQLD 116
Query: 134 ISPEKKAKVLETIVKASNELCEGQALDLEFENREMVSIE-EYMRMISGKTGALFDASAKV 192
PE + E ++ EL GQ +++ + + E +Y M KTG LF + ++
Sbjct: 117 -HPEVRKVYTEQLL----ELHRGQGMEIYWRDSFTCPSESDYKLMTVRKTGGLFMLAIRL 171
Query: 193 GGIVGTENEEYIEALSRWGRNVGMAFQIWDDVLDLIADEEKLGKPVGSDIRKGKKTLIVA 252
+ + E+Y S+ +G+ FQI DD +L E + K D+ +GK V
Sbjct: 172 MQLFSSNKEDY----SKLTAILGLYFQIRDDYCNLSLKEVSVNKSFAEDLTEGKFGFPVI 227
Query: 253 HFFENADEKAKEKFLKVFGKYAGDVKGKGIIEEDVKAEVMEAIELLKEHGSIDYASRIAR 312
H +K ++ L+ + D++ K I LL++ GS Y ++
Sbjct: 228 HAVRT--QKQDKQVLRKSSQRTHDIEVK-----------KYCITLLEKLGSFQYTRKVLE 274
Query: 313 ELVEKANEALNVL 325
L +A ++ L
Sbjct: 275 SLDAEARSEVSTL 287
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.136 0.376
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119347797
Number of Sequences: 2977
Number of extensions: 4892315
Number of successful extensions: 17713
Number of sequences better than 1.0e-10: 177
Number of HSP's better than 0.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 17272
Number of HSP's gapped (non-prelim): 185
length of query: 346
length of database: 189,106,746
effective HSP length: 59
effective length of query: 287
effective length of database: 153,796,013
effective search space: 44139455731
effective search space used: 44139455731
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)