BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2405 (gptA) DE:purine phosphoribosyltransferase
(215 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75215 purine phosphoribosyltransferase PAB2405 - Pyrococcu... 451 e-126
pir||H71451 hypothetical protein PH0271 - Pyrococcus horikoshii ... 432 e-120
emb|CAC12472.1| (AL445067) purine phosphoribosyltransferase rela... 195 4e-49
gb|AAK42493.1| Purine phosphoribosyltransferase (gpT-1) [Sulfolo... 164 1e-39
gi|11497855 xanthine-guanine phosphoribosyltransferase (gptA-1) ... 160 2e-38
pir||C72745 hypothetical protein APE0490 - Aeropyrum pernix (str... 148 5e-35
gb|AAG18909.1| (AE004993) purine phosphoribosyltransferase; GptA... 144 1e-33
pir||A72512 probable hypoxanthine phosphoribosyltransferase APE2... 102 3e-21
gi|11499378 xanthine-guanine phosphoribosyltransferase (gptA-2) ... 102 3e-21
gb|AAK42568.1| Purine phosphoribosyltransferase (gpT-2) [Sulfolo... 101 6e-21
pir||A75197 purine phosphoribosyltransferase related protein PAB... 74 1e-12
pir||E71229 probable purine phosphoribosyltransferase - Pyrococc... 71 8e-12
>pir||D75215 purine phosphoribosyltransferase PAB2405 - Pyrococcus abyssi
(strain Orsay) >gi|5457680|emb|CAB49171.1| (AJ248283)
purine phosphoribosyltransferase [Pyrococcus abyssi]
Length = 215
Score = 451 bits (1148), Expect = e-126
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MKAFPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVS 60
MKAFPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVS
Sbjct: 1 MKAFPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVS 60
Query: 61 IKVEHWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIR 120
IKVEHWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIR
Sbjct: 61 IKVEHWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIR 120
Query: 121 TATLLNIKGSKFVPDYYAKDIDWAWIIFPWNFVEDMINLTNNLFEEKERLTTEEIISLFK 180
TATLLNIKGSKFVPDYYAKDIDWAWIIFPWNFVEDMINLTNNLFEEKERLTTEEIISLFK
Sbjct: 121 TATLLNIKGSKFVPDYYAKDIDWAWIIFPWNFVEDMINLTNNLFEEKERLTTEEIISLFK 180
Query: 181 ELHGIEVPKEKLEEALKMAEKRNIFKFENGFWVKV 215
ELHGIEVPKEKLEEALKMAEKRNIFKFENGFWVKV
Sbjct: 181 ELHGIEVPKEKLEEALKMAEKRNIFKFENGFWVKV 215
>pir||H71451 hypothetical protein PH0271 - Pyrococcus horikoshii
>gi|3256660|dbj|BAA29343.1| (AP000001) 215aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 215
Score = 432 bits (1099), Expect = e-120
Identities = 198/215 (92%), Positives = 211/215 (98%)
Query: 1 MKAFPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVS 60
MKAFPAYLASW+DIEEWAK GAWKVLESGWMPDV+VGLARGGWIAARLYCDYLGVKDLVS
Sbjct: 1 MKAFPAYLASWEDIEEWAKTGAWKVLESGWMPDVIVGLARGGWIAARLYCDYLGVKDLVS 60
Query: 61 IKVEHWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIR 120
+KVEHWGITATPDGRARLKYG QYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEI+
Sbjct: 61 VKVEHWGITATPDGRARLKYGTQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIK 120
Query: 121 TATLLNIKGSKFVPDYYAKDIDWAWIIFPWNFVEDMINLTNNLFEEKERLTTEEIISLFK 180
TATLLNIKGSKF+PDYYAKDIDW W++FPWNFVEDMINLT+NLFEEKE+LT EEI+SLFK
Sbjct: 121 TATLLNIKGSKFIPDYYAKDIDWVWVVFPWNFVEDMINLTSNLFEEKEKLTIEEIVSLFK 180
Query: 181 ELHGIEVPKEKLEEALKMAEKRNIFKFENGFWVKV 215
ELHGIEVPKEKLEEAL++AEKRNIFKFENGFW+KV
Sbjct: 181 ELHGIEVPKEKLEEALRIAEKRNIFKFENGFWMKV 215
>emb|CAC12472.1| (AL445067) purine phosphoribosyltransferase related protein
[Thermoplasma acidophilum]
Length = 217
Score = 195 bits (490), Expect = 4e-49
Identities = 99/196 (50%), Positives = 131/196 (66%), Gaps = 6/196 (3%)
Query: 4 FPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKV 63
F A L SW DI+ W + KV ++ + D ++G+ARGG + AR+ D L VKDL+S+K
Sbjct: 5 FKATLVSWADIDRWCGNISRKV-QASFDVDTIIGIARGGLVPARILSDRLWVKDLLSVKT 63
Query: 64 EHWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTAT 123
EHWGITAT DG A LK D GK VL+VDDITDTGESMSLAY+Y+KS P E+R+AT
Sbjct: 64 EHWGITATKDGEAVLKTKINMDLSGKNVLVVDDITDTGESMSLAYDYVKSLKPRELRSAT 123
Query: 124 LLNIKGSKFVPDYYAKDI---DWAWIIFPWNFVEDMINLTNNLFEEKERLTTEEIISLFK 180
+L+I SKFVPDYY++ I +WAW IFPWN ED+ NL F +R+ +E++ K
Sbjct: 124 MLHISRSKFVPDYYSELITEKNWAWFIFPWNVYEDLNNLIRKSF--TDRINADEVVDALK 181
Query: 181 ELHGIEVPKEKLEEAL 196
E + ++V +EE L
Sbjct: 182 EDYDLDVSSLNMEEIL 197
>gb|AAK42493.1| Purine phosphoribosyltransferase (gpT-1) [Sulfolobus solfataricus]
Length = 210
Score = 164 bits (410), Expect = 1e-39
Identities = 88/209 (42%), Positives = 131/209 (62%), Gaps = 5/209 (2%)
Query: 1 MKAFPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVS 60
M+ P + +WD+I + A K+ + +V+V +ARGG + ARL D LGV D++S
Sbjct: 1 MQKIPVKVVTWDEIVSLSTKLAEKIKADEYNVNVIVAIARGGLVPARLVADVLGVFDILS 60
Query: 61 IKVEHWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEY-MKSRNPAEI 119
IK+EHW TA+ A++KY + D K VLI+DDITDTG+S+ LA +Y M++ P E+
Sbjct: 61 IKIEHWIETASHTPEAKVKYPFKVDLSDKNVLIIDDITDTGDSIELARKYVMENFRPTEV 120
Query: 120 RTATLLNIK-GSKFVPDYYAKDI-DWAWIIFPWNFVEDMINLTNNLFEEKER--LTTEEI 175
+TATL IK +K +PDYYA++I WAW ++PWN+ ED INL N + E++ + E+
Sbjct: 121 KTATLQYIKPAAKIIPDYYAEEIVSWAWFMYPWNYWEDEINLVNKILIERKTKDIDINEL 180
Query: 176 ISLFKELHGIEVPKEKLEEALKMAEKRNI 204
F E +GIE P L++ L ++R I
Sbjct: 181 KRNFVESYGIENPPISLDKILTEMKRRKI 209
>gi|11497855 xanthine-guanine phosphoribosyltransferase (gptA-1) [Archaeoglobus
fulgidus] >gi|7484010|pir||G69279 xanthine-guanine
phosphoribosyltransferase (gptA-1) homolog -
Archaeoglobus fulgidus >gi|2650402|gb|AAB90994.1|
(AE001089) xanthine-guanine phosphoribosyltransferase
(gptA-1) [Archaeoglobus fulgidus]
Length = 194
Score = 160 bits (400), Expect = 2e-38
Identities = 78/194 (40%), Positives = 117/194 (60%), Gaps = 6/194 (3%)
Query: 4 FPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKV 63
F L +WD+I + K A KV ESG+ PD VV +ARGGW+ AR+ CDYL +++L S+K
Sbjct: 3 FKCVLYTWDEIRKLCKELAMKVRESGYQPDAVVAIARGGWVPARIVCDYLDIRELYSVKT 62
Query: 64 EHWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTAT 123
EHW + A A++ D GKK+LIVDD+ DTG+++ + +++ PAEIR A
Sbjct: 63 EHWDV-AEKREEAKITQPLNVDVSGKKILIVDDVADTGDTIRVVVDHVNQYRPAEIRVAV 121
Query: 124 LLNIKGSKFVPDYYAKDID-WAWIIFPWNFVEDMINLTNNLFEEKERLTTEEIISLFKEL 182
+ SKFVPDYYA ++ W WI++PW+ E++ +L E+ T +E + KE
Sbjct: 122 VDYKTTSKFVPDYYAAKMEAWRWIVYPWSVKEEL----RDLIEKVNAKTVDEAVRALKEE 177
Query: 183 HGIEVPKEKLEEAL 196
+EV +E + + L
Sbjct: 178 FDLEVDEELVRDVL 191
>pir||C72745 hypothetical protein APE0490 - Aeropyrum pernix (strain K1)
>gi|5104139|dbj|BAA79455.1| (AP000059) 226aa long
hypothetical protein [Aeropyrum pernix]
Length = 226
Score = 148 bits (370), Expect = 5e-35
Identities = 79/190 (41%), Positives = 113/190 (58%), Gaps = 8/190 (4%)
Query: 5 PAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKVE 64
P L W DI EW+ + + ESG+ PDVV+ ++RGG++ ARL CD+L V +L+SI+ +
Sbjct: 2 PVKLVDWSDIVEWSLGLSNMIRESGYEPDVVIAVSRGGFVPARLLCDFLDVTNLLSIQSQ 61
Query: 65 HWGITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYM-KSRNPAEIRTAT 123
HW A +A LK+ + D G K L+VDDI DTG+++ LA E++ K P E+R A
Sbjct: 62 HWVEAARMAEKAILKFPYRVDLSGLKALLVDDIVDTGDTLLLAKEFIEKEWKPGELRVAA 121
Query: 124 LLNIKG-SKFVPDYYAKDI-DWAWIIFPWNFVEDMINLTNNLFEEKERL-----TTEEII 176
L I +KF PDYY ++ +WAW +PW +ED + LF E E L E++
Sbjct: 122 LQWISSVAKFKPDYYYMEVREWAWFQYPWTRLEDTMQFITRLFREHEDLRGKAVAPEKLE 181
Query: 177 SLFKELHGIE 186
FKE +GIE
Sbjct: 182 EAFKEFYGIE 191
>gb|AAG18909.1| (AE004993) purine phosphoribosyltransferase; GptA1 [Halobacterium
sp. NRC-1]
Length = 230
Score = 144 bits (359), Expect = 1e-33
Identities = 76/204 (37%), Positives = 121/204 (59%), Gaps = 4/204 (1%)
Query: 4 FPAYLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKV 63
F + +W+ I + + +V + + PDVVV LARGGW A R CD+LG+ DL S+K+
Sbjct: 8 FNCTITNWEYIYGLCRDVSDQVKAADFEPDVVVALARGGWFAGRCLCDFLGLNDLTSLKM 67
Query: 64 EHWGITATPDGRARLKYG-AQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTA 122
EH+ TA ++Y + E K VLI+DDI DTG S+ A+EY++ R+ +RTA
Sbjct: 68 EHYVGTAEKSAEPEVRYPMPEGSVEDKDVLIIDDIADTGGSIEHAHEYVQDRDANAVRTA 127
Query: 123 TLLNIKGSKFVPDYYAKDID-WAWIIFPWNFVEDMINLTNNLF--EEKERLTTEEIISLF 179
TL ++ S F PDY + +D WAWI++PWNF+EDMI++ + ++ TT I L
Sbjct: 128 TLQLLQTSAFEPDYVGERLDEWAWIVYPWNFIEDMIDIIAGVMATDDDGPYTTAGIRDLL 187
Query: 180 KELHGIEVPKEKLEEALKMAEKRN 203
+ H ++ + ++ + ++ E R+
Sbjct: 188 ADYHDVDRIQMEIAQPDRLTEVRS 211
>pir||A72512 probable hypoxanthine phosphoribosyltransferase APE2071 - Aeropyrum
pernix (strain K1) >gi|5105769|dbj|BAA81081.1|
(AP000063) 272aa long hypothetical hypoxanthine
phosphoribosyltransferase [Aeropyrum pernix]
Length = 272
Score = 102 bits (253), Expect = 3e-21
Identities = 53/141 (37%), Positives = 86/141 (60%), Gaps = 1/141 (0%)
Query: 10 SWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKVEHWGIT 69
SW DIE+ + A K++ SG+ PDV+VG+ RGG + A L D LGVK++ ++++ +
Sbjct: 117 SWRDIEDAVRDVADKIVGSGFEPDVIVGILRGGIVPALLLADALGVKNIGVMEIKLYTSV 176
Query: 70 ATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTATLLNIKG 129
R L+ + + + VL+VDD++D+G ++ A E + PA+++TATL
Sbjct: 177 GVRKPRPFLRQPLVIEVKDRNVLVVDDVSDSGLTLQHAIEAVDLYLPAQVKTATLYIKPW 236
Query: 130 SKFVPDYYAKDIDWAWIIFPW 150
+ VPDYY+K +D WI+FPW
Sbjct: 237 TNLVPDYYSKSLD-KWIVFPW 256
>gi|11499378 xanthine-guanine phosphoribosyltransferase (gptA-2) [Archaeoglobus
fulgidus] >gi|7484011|pir||D69473 xanthine-guanine
phosphoribosyltransferase (gptA-2) homolog -
Archaeoglobus fulgidus >gi|2648768|gb|AAB89468.1|
(AE000979) xanthine-guanine phosphoribosyltransferase
(gptA-2) [Archaeoglobus fulgidus]
Length = 203
Score = 102 bits (252), Expect = 3e-21
Identities = 61/203 (30%), Positives = 112/203 (55%), Gaps = 25/203 (12%)
Query: 10 SWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKVEHWGIT 69
SW +E + A++++E ++P+ +V LA+GG L DYLGV +V + V+
Sbjct: 6 SWRYVESLCRKIAFEIVEDKFIPERIVALAKGGIFVGSLLSDYLGVSRIVCLDVK----- 60
Query: 70 ATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTATLLNIKG 129
DG+ ++ G ++L+VDD +TG++MS A E ++ E+RTA+LL ++
Sbjct: 61 ---DGKEKV--------GGSRLLVVDDFINTGKTMSRALELVEG---DEVRTASLLMLEK 106
Query: 130 SKFVPDYYAKDI-DWAWIIFPWNFVEDMINLTNNLFEEKERLTTEEIISLFKE----LHG 184
S F+PDY + ++ W+IFPWN ED+ +L + + E+ ++ ++ + E +H
Sbjct: 107 SDFIPDYLGDYLTEYYWVIFPWNVFEDISSLISEILREEGEMSQSKLRRIVSERGLNIHS 166
Query: 185 IE-VPKEKLEEALKMAEKRNIFK 206
+E V K E+ L+ E + + +
Sbjct: 167 LEAVFPGKFEDVLEFMELKGLIE 189
>gb|AAK42568.1| Purine phosphoribosyltransferase (gpT-2) [Sulfolobus solfataricus]
Length = 179
Score = 101 bits (250), Expect = 6e-21
Identities = 55/163 (33%), Positives = 93/163 (56%), Gaps = 1/163 (0%)
Query: 7 YLASWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKVEHW 66
++ SWD+IE+ + +++S ++PDV++ + GG I A+L D L +K + I ++ +
Sbjct: 5 HIPSWDEIEDAVFSIGEALVKSNYIPDVLIAVLTGGIIPAKLLSDLLDLKVIRYIDIKFY 64
Query: 67 GITATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTATLLN 126
+ + ++ EGKKVL+VDD+ DTGE++ + NPA++ TA L
Sbjct: 65 RSVGKTESKPVIRSVYTDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVMTAALYL 124
Query: 127 IKGSKFVPDYYAKDIDWAWIIFPWNFVEDMINLTNNLFEEKER 169
SK +PD+Y K ID WIIFPW+ + + +N ++KER
Sbjct: 125 KPWSKRIPDFYYKQID-KWIIFPWDKWDVVRENSNVPVDKKER 166
>pir||A75197 purine phosphoribosyltransferase related protein PAB0060 -
Pyrococcus abyssi (strain Orsay)
>gi|5457533|emb|CAB49024.1| (AJ248283) PURINE
PHOSPHORIBOSYLTRANSFERASE related protein [Pyrococcus
abyssi]
Length = 153
Score = 74.1 bits (179), Expect = 1e-12
Identities = 48/141 (34%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query: 10 SWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKVEHWGIT 69
+W ++ A A K+ E + PDV+VG+ARGG I A L L I V+ +
Sbjct: 7 TWWQVDRAIFALAEKLRE--YKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGI 64
Query: 70 ATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTATLLNIKG 129
+ + D +GKKV+IVDD++DTG+++ + + +K EI+ A L
Sbjct: 65 DERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAMKPW 124
Query: 130 SKFVPDYYAKDIDWAWIIFPW 150
+ VPDYY D WI+FPW
Sbjct: 125 TSVVPDYYVFRTD-KWIVFPW 144
>pir||E71229 probable purine phosphoribosyltransferase - Pyrococcus horikoshii
>gi|3256481|dbj|BAA29164.1| (AP000001) 153aa long
hypothetical purine phosphoribosyltransferase
[Pyrococcus horikoshii]
Length = 153
Score = 71.4 bits (172), Expect = 8e-12
Identities = 46/141 (32%), Positives = 72/141 (50%), Gaps = 3/141 (2%)
Query: 10 SWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKVEHWGIT 69
+W ++ A A K+ E + PDV++G+ARGG I A LG L I V+ +
Sbjct: 7 TWWQVDRAIFALAEKLRE--YKPDVIIGVARGGLIPAVRLSHILGDIPLKVIDVKFYKGI 64
Query: 70 ATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTATLLNIKG 129
+ + D + K+V+IVDD++DTG+++ + E +K EI+ A L
Sbjct: 65 DERGEKPVITIPIHGDLKDKRVVIVDDVSDTGKTLEVVIEEVKKLGAKEIKIACLAMKPW 124
Query: 130 SKFVPDYYAKDIDWAWIIFPW 150
+ VPDYY + WI+FPW
Sbjct: 125 TSVVPDYYVFRTE-KWIVFPW 144
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.138 0.432
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86187509
Number of Sequences: 2977
Number of extensions: 3576045
Number of successful extensions: 11101
Number of sequences better than 1.0e-10: 12
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 11072
Number of HSP's gapped (non-prelim): 13
length of query: 215
length of database: 189,106,746
effective HSP length: 50
effective length of query: 165
effective length of database: 159,182,396
effective search space: 26265095340
effective search space used: 26265095340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 163 (67.9 bits)