BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2414 (AGPA) DE:Alpha-glucan phosphorylase
(835 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75107 alpha-glucan phosphorylase PAB2414 - Pyrococcus abys... 1725 0.0
pir||D71027 hypothetical protein PH1512 - Pyrococcus horikoshii ... 1543 0.0
gb|AAD28735.1|AF115479_1 (AF115479) maltodextrin phosphorylase [... 1232 0.0
emb|CAA04523.1| (AJ001088) alpha-glucan phosphorylase [Thermotog... 1031 0.0
pir||D75304 probable alpha-glucan phosphorylase - Deinococcus ra... 623 e-177
dbj|BAB11741.1| (AB047267) alpha-glucan phosphorylase [Thermus a... 584 e-165
sp|O66932|PHSG_AQUAE GLYCOGEN PHOSPHORYLASE >gi|7514959|pir||H70... 564 e-159
sp|Q10639|PHSG_MYCTU GLYCOGEN PHOSPHORYLASE >gi|7478100|pir||D70... 550 e-155
emb|CAB40105.1| (AJ001205) putative glycogen phosphorylase [Stre... 536 e-151
emb|CAB72420.1| (AL138978) putative glycogen phosphorylase [Stre... 488 e-137
sp|Q59025|YG31_METJA HYPOTHETICAL PROTEIN MJ1631 >gi|2128981|pir... 237 4e-61
gb|AAK42667.1| Glucan phosphorylase, putative (glgP or malP) [Su... 106 1e-21
sp|P45180|PHSG_HAEIN GLYCOGEN PHOSPHORYLASE >gi|1073835|pir||D64... 103 7e-21
pir||T45633 starch phosphorylase (EC 2.4.1.1) H, cytosolic F13I1... 102 2e-20
gb|AAF39800.1| (AC006636) contains similarity to Pfam domain PF0... 101 3e-20
dbj|BAB04803.1| (AP001510) glycogen phosphorylase [Bacillus halo... 100 8e-20
sp|P53537|PHSH_VICFA ALPHA-GLUCAN PHOSPHORYLASE, H ISOZYME (STAR... 98 3e-19
gb|AAA58226.1| (U18997) alpha-glucan phosphorylase [Escherichia ... 94 8e-18
sp|P13031|PHSG_ECOLI GLYCOGEN PHOSPHORYLASE >gi|7427924|pir||PHE... 94 8e-18
gb|AAA23874.1| (J03966) alpha-glucan phosphorylase (EC 2.4.1.1) ... 94 8e-18
emb|CAA34807.1| (X16931) glycogen phosphorylase (AA 1 - 790) [Es... 91 4e-17
sp|P39123|PHSG_BACSU GLYCOGEN PHOSPHORYLASE >gi|480288|pir||S366... 91 5e-17
sp|P32811|PHSH_SOLTU ALPHA-GLUCAN PHOSPHORYLASE, H ISOZYME (STAR... 91 5e-17
gi|11560087 liver glycogen phosphorylase [Rattus norvegicus] >gi... 90 9e-17
pir||A82511 maltodextrin phosphorylase VCA0013 [imported] - Vibr... 89 2e-16
emb|CAA44069.1| (X62142) glycogen phosphorylase 1 [Dictyostelium... 89 2e-16
sp|Q00766|PHS1_DICDI GLYCOGEN PHOSPHORYLASE 1 (GP1) >gi|478597|p... 89 2e-16
gb|AAD46887.1|AF160947_1 (AF160947) BcDNA.LD24485 [Drosophila me... 89 3e-16
gi|4506353 phosphorylase, glycogen; liver (Hers disease, glycoge... 88 5e-16
pdb|1FA9|A Chain A, Human Liver Glycogen Phosphorylase A Complex... 88 5e-16
pdb|1FC0|A Chain A, Human Liver Glycogen Phosphorylase Complexed... 88 5e-16
gb|AAD27759.1|AF073178_1 (AF073178) glycogen phosphorylase [Dros... 87 1e-15
gb|AAG00588.1|AF288783_1 (AF288783) glycogen phosphorylase [Mus ... 85 2e-15
gb|AAC17450.1| (AF066858) liver glycogen phosphorylase [Homo sap... 85 2e-15
gb|AAC18079.1| (AF046798) glycogen phosphorylase [Homo sapiens] ... 85 3e-15
pir||A25518 glycogen phosphorylase (EC 2.4.1.1), hepatic - human... 84 5e-15
gb|AAB68800.1| (AF001899) glycogen myophosphorylase [Ovis aries] 83 1e-14
pir||S77252 phosphorylase (EC 2.4.1.1) 2 - Synechocystis sp. (st... 83 2e-14
prf||0401194A phosphorylase b,glycogen [Oryctolagus cuniculus] 82 2e-14
gb|AAB46846.1| (S82859) alpha-1,4-glucan orthophosphate glycosyl... 82 2e-14
sp|P34114|PHS2_DICDI GLYCOGEN PHOSPHORYLASE 2 (GP2) >gi|283457|p... 82 3e-14
gb|AAD03471.1| (AF033856) glycogen phosphorylase [Agrobacterium ... 81 5e-14
prf||1402394A glycogen phosphorylase [Homo sapiens] 81 5e-14
pdb|1C8K|A Chain A, Flavopiridol Inhibits Glycogen Phosphorylase... 80 8e-14
pdb|8GPB| Glycogen Phosphorylase b (E.C.2.4.1.1) (T State) Com... 80 8e-14
pdb|1ABB|A Chain A, Glycogen Phosphorylase (E.C.2.4.1.1) Complex... 80 8e-14
pdb|1C50|A Chain A, Identification And Structural Characterizati... 80 8e-14
sp|P00489|PHS2_RABIT GLYCOGEN PHOSPHORYLASE, MUSCLE FORM (MYOPHO... 80 1e-13
prf||1103304A phosphorylase,maltodextrin [Escherichia coli] 80 1e-13
pdb|1E1Y|A Chain A, Lavopiridol Inhibits Glycogen Phosphorylase ... 80 1e-13
sp|Q9Z8N1|PHSG_CHLPN GLYCOGEN PHOSPHORYLASE >gi|7433827|pir||C72... 80 1e-13
pdb|1C8L|A Chain A, Synergistic Inhibition Of Glycogen Phosphory... 80 1e-13
gb|AAD53957.1|AF181035_1 (AF181035) glycogen phosphorylase [Rhod... 80 1e-13
pir||S34624 glycogen phosphorylase (EC 2.4.1.1), muscle - rat (f... 79 2e-13
gb|AAA58215.1| (U18997) maltodextrin phosphorylase [Escherichia ... 79 2e-13
sp|P09812|PHS2_RAT GLYCOGEN PHOSPHORYLASE, MUSCLE FORM (MYOPHOSP... 79 2e-13
pir||PHECGM phosphorylase (EC 2.4.1.1) malP - Escherichia coli >... 79 2e-13
gi|6755256 muscle glycogen phosphorylase [Mus musculus] >gi|4836... 79 2e-13
pdb|1E4O|A Chain A, Phosphorylase Recognition And Phosphorolysis... 79 2e-13
pir||S00596 maltodextrin phosphorylase (EC 2.4.1.1) - Escherichi... 78 3e-13
pdb|1NOJ| Complex Of Glycogen Phosphorylase With A Transition ... 78 3e-13
pdb|1AHP|A Chain A, Oligosaccharide Substrate Binding In Escheri... 78 3e-13
pdb|2ECP|A Chain A, The Crystal Structure Of The E. Coli Maltode... 78 3e-13
emb|CAA29949.1| (X06791) maltodextrin phosphorylase [Escherichia... 78 4e-13
sp|P00490|PHSM_ECOLI MALTODEXTRIN PHOSPHORYLASE 78 4e-13
pdb|1A8I| Spirohydantoin Inhibitor Of Glycogen Phosphorylase >... 78 4e-13
emb|CAA27816.1| (X04265) glycogen phosphorylase (aa 1-843) [Oryc... 78 5e-13
pir||A83379 glycogen phosphorylase PA2144 [imported] - Pseudomon... 77 7e-13
pir||A27335 glycogen phosphorylase (EC 2.4.1.1), muscle - human ... 77 7e-13
gi|5032009 phosphorylase, glycogen; muscle (McArdle syndrome, gl... 77 7e-13
pir||A29949 glycogen phosphorylase (EC 2.4.1.1), brain (astrocyt... 76 2e-12
sp|P73511|PHSG_SYNY3 GLYCOGEN PHOSPHORYLASE >gi|7433823|pir||S77... 73 1e-11
gi|4506351 phosphorylase, glycogen; brain [Homo sapiens] >gi|173... 72 2e-11
gi|11420375 phosphorylase, glycogen; brain [Homo sapiens] >gi|96... 72 2e-11
sp|P53534|PHS3_RAT GLYCOGEN PHOSPHORYLASE, BRAIN FORM >gi|204421... 71 7e-11
pir||S37300 glycogen phosphorylase (EC 2.4.1.1), brain - rat 71 7e-11
>pir||A75107 alpha-glucan phosphorylase PAB2414 - Pyrococcus abyssi (strain
Orsay) >gi|5458081|emb|CAB49570.1| (AJ248285)
Alpha-glucan phosphorylase [Pyrococcus abyssi]
Length = 835
Score = 1725 bits (4418), Expect = 0.0
Identities = 835/835 (100%), Positives = 835/835 (100%)
Query: 1 MKVDNSVKERILRRLPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYKNPVKLLL 60
MKVDNSVKERILRRLPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYKNPVKLLL
Sbjct: 1 MKVDNSVKERILRRLPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYKNPVKLLL 60
Query: 61 EVPESRLRQLSRDDSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGK 120
EVPESRLRQLSRDDSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGK
Sbjct: 61 EVPESRLRQLSRDDSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGK 120
Query: 121 SLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIRE 180
SLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIRE
Sbjct: 121 SLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIRE 180
Query: 181 MPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYL 240
MPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYL
Sbjct: 181 MPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYL 240
Query: 241 YNAEPDKRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEE 300
YNAEPDKRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEE
Sbjct: 241 YNAEPDKRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEE 300
Query: 301 ALELVRATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVTPEDTNFNM 360
ALELVRATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVTPEDTNFNM
Sbjct: 301 ALELVRATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVTPEDTNFNM 360
Query: 361 TVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKL 420
TVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKL
Sbjct: 361 TVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKL 420
Query: 421 YDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDE 480
YDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDE
Sbjct: 421 YDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDE 480
Query: 481 PLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAG 540
PLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAG
Sbjct: 481 PLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAG 540
Query: 541 KEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAG 600
KEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAG
Sbjct: 541 KEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAG 600
Query: 601 LNGVINLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYE 660
LNGVINLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYE
Sbjct: 601 LNGVINLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYE 660
Query: 661 NRSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLSRDNFKWAKELAKWKE 720
NRSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLSRDNFKWAKELAKWKE
Sbjct: 661 NRSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLSRDNFKWAKELAKWKE 720
Query: 721 KIRREWGEVEIEDAKVSEDSIEVTLRLGNLRPEDVRVELYYGVKGDGKIAEPSTVELRKM 780
KIRREWGEVEIEDAKVSEDSIEVTLRLGNLRPEDVRVELYYGVKGDGKIAEPSTVELRKM
Sbjct: 721 KIRREWGEVEIEDAKVSEDSIEVTLRLGNLRPEDVRVELYYGVKGDGKIAEPSTVELRKM 780
Query: 781 KELGDGRYVYSYSGKALKYINHDCWHYSVRVYAYHSMIPGKFLLGGYIKWKVLKN 835
KELGDGRYVYSYSGKALKYINHDCWHYSVRVYAYHSMIPGKFLLGGYIKWKVLKN
Sbjct: 781 KELGDGRYVYSYSGKALKYINHDCWHYSVRVYAYHSMIPGKFLLGGYIKWKVLKN 835
>pir||D71027 hypothetical protein PH1512 - Pyrococcus horikoshii
>gi|3257937|dbj|BAA30620.1| (AP000006) 837aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 837
Score = 1543 bits (3952), Expect = 0.0
Identities = 721/834 (86%), Positives = 785/834 (93%)
Query: 1 MKVDNSVKERILRRLPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYKNPVKLLL 60
MKVDNS KERIL +LPEN+S+LADLAYNYWWSWD KAMKLWQ+IDEEHWREYKNPVKLLL
Sbjct: 4 MKVDNSTKERILEKLPENLSRLADLAYNYWWSWDHKAMKLWQKIDEEHWREYKNPVKLLL 63
Query: 61 EVPESRLRQLSRDDSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGK 120
E PESRLR+LSRDD+FLDLYELVIERF++YM+ T TW + NYPRWDKPI+YLCMEYGIGK
Sbjct: 64 EAPESRLRELSRDDNFLDLYELVIERFDDYMKETATWFSTNYPRWDKPIIYLCMEYGIGK 123
Query: 121 SLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIRE 180
SLPIYSGGLGILAGDHLKTASDLGLP++AIGLLYKHGYFKQEID +GRQIE+FPEYN++E
Sbjct: 124 SLPIYSGGLGILAGDHLKTASDLGLPMVAIGLLYKHGYFKQEIDINGRQIERFPEYNVKE 183
Query: 181 MPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYL 240
MPIRQVL+NDG+PLLIDVPIEDR++KARVFLVEVGRVKLYLLDTDVPEN E DR+ICDYL
Sbjct: 184 MPIRQVLDNDGSPLLIDVPIEDRMIKARVFLVEVGRVKLYLLDTDVPENSEADRKICDYL 243
Query: 241 YNAEPDKRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEE 300
YNAEPDKRIKQEILIGIGGMRLLKALEI+PGV+HLNEGH +FANFERIRWF+EKGL+FEE
Sbjct: 244 YNAEPDKRIKQEILIGIGGMRLLKALEIDPGVVHLNEGHAAFANFERIRWFIEKGLSFEE 303
Query: 301 ALELVRATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVTPEDTNFNM 360
ALE+VR TSVFTTHTPVPAGHDVFPV+FVREKLR F LP+DK LGLGKV D NFNM
Sbjct: 304 ALEIVRGTSVFTTHTPVPAGHDVFPVEFVREKLRAFFDGLPEDKLLGLGKVNDSDPNFNM 363
Query: 361 TVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKL 420
TVL+IRTSEFVNAVSKLHAKVTREMW+NLWPGVP DEIPI+ ITNG+HTPTWVNENLAKL
Sbjct: 364 TVLAIRTSEFVNAVSKLHAKVTREMWANLWPGVPPDEIPIEPITNGIHTPTWVNENLAKL 423
Query: 421 YDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDE 480
Y+IYIGKIWREHVNLEGIWYAIERIPD ELWEAHLKAKRE+IELIRRKIMKRNERLGIDE
Sbjct: 424 YEIYIGKIWREHVNLEGIWYAIERIPDHELWEAHLKAKRELIELIRRKIMKRNERLGIDE 483
Query: 481 PLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAG 540
P+PD+DENALIIGFARRFATYKRAILLFTDLERLKRIVNN +RPVYIIFGGKAHPMDEAG
Sbjct: 484 PIPDVDENALIIGFARRFATYKRAILLFTDLERLKRIVNNRDRPVYIIFGGKAHPMDEAG 543
Query: 541 KEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAG 600
KE+LRRVYEVSQMPEFKGKIILIENYD+GSARIL+SGVDVWLNTP+RPLEASGTSGMKAG
Sbjct: 544 KEYLRRVYEVSQMPEFKGKIILIENYDLGSARILISGVDVWLNTPKRPLEASGTSGMKAG 603
Query: 601 LNGVINLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYE 660
LNGV+NLS FDGWWVEGYNGRNGWVIGDATLEPETE DDYLDAMSLYDLLENVV+P+YYE
Sbjct: 604 LNGVLNLSTFDGWWVEGYNGRNGWVIGDATLEPETEEDDYLDAMSLYDLLENVVIPMYYE 663
Query: 661 NRSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLSRDNFKWAKELAKWKE 720
NR WIR+MKESI SIAPRFSTYRM+KEY++KFYSRAMETG+YLSRDNF+WAKELA WKE
Sbjct: 664 NREGWIRIMKESIKSIAPRFSTYRMLKEYMTKFYSRAMETGIYLSRDNFRWAKELASWKE 723
Query: 721 KIRREWGEVEIEDAKVSEDSIEVTLRLGNLRPEDVRVELYYGVKGDGKIAEPSTVELRKM 780
KI W +VEIED KV+E+ IE +RLG +RPEDVRVELYYGV+GDGKI EP TVELRK
Sbjct: 724 KIMLGWNDVEIEDVKVNENRIEAIIRLGTIRPEDVRVELYYGVRGDGKIMEPYTVELRKT 783
Query: 781 KELGDGRYVYSYSGKALKYINHDCWHYSVRVYAYHSMIPGKFLLGGYIKWKVLK 834
KELG G+Y+Y+YSGKALK NH+CWHYS+RVYAYH MIPGKFLLGGYIKW+ LK
Sbjct: 784 KELGTGKYLYTYSGKALKNFNHECWHYSIRVYAYHPMIPGKFLLGGYIKWRDLK 837
>gb|AAD28735.1|AF115479_1 (AF115479) maltodextrin phosphorylase [Thermococcus litoralis]
Length = 831
Score = 1232 bits (3154), Expect = 0.0
Identities = 577/829 (69%), Positives = 686/829 (82%), Gaps = 8/829 (0%)
Query: 6 SVKERILRRLPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYKNPVKLLLEVPES 65
+V +I +LPEN+ L DLAYNYWWSW+ +A KLW++ID EHW EYKNPVKLLL+ PE
Sbjct: 3 TVVNQIKSKLPENLEGLLDLAYNYWWSWNRRATKLWEKIDPEHWWEYKNPVKLLLDTPEE 62
Query: 66 RLRQLSRDDSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGKSLPIY 125
RL++LS+DD F++LYELVI++F +YM +TW + NYP+W++P++YLCMEYGI KSLPIY
Sbjct: 63 RLKELSKDDDFINLYELVIDQFRHYMNPESTWFSTNYPKWEEPVIYLCMEYGISKSLPIY 122
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQ 185
SGGLGILAGDH+KTASDLG+PLIAIGLLYKHGYFKQEID+DG+QIE FPEYN EMPI+
Sbjct: 123 SGGLGILAGDHIKTASDLGIPLIAIGLLYKHGYFKQEIDKDGKQIEVFPEYNPEEMPIKP 182
Query: 186 VLNNDGTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEP 245
+ G PLLI+VPIEDRIV AR F V VGRVKLYLLDTDVP+N DDR ICDYLYNAE
Sbjct: 183 LTTEKGKPLLIEVPIEDRIVYARAFEVNVGRVKLYLLDTDVPQNSPDDRTICDYLYNAEI 242
Query: 246 DKRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEALELV 305
DKRIKQEIL+GIGGMRLL+ L I+P VIHLNEGHP+FANF+RI W+ME+GL F EAL +V
Sbjct: 243 DKRIKQEILLGIGGMRLLRMLGIDPAVIHLNEGHPAFANFQRIAWYMEEGLNFLEALTVV 302
Query: 306 RATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVTPEDTNFNMTVLSI 365
R T++FTTHTPVPAGHD FP+ V ++L FL LP+D+FL LG+ E FNMT+LSI
Sbjct: 303 RGTTIFTTHTPVPAGHDKFPIAEVEKRLAKFLEGLPKDEFLNLGR---EGDQFNMTLLSI 359
Query: 366 RTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYI 425
RTS +VNAVSKLH+KVT+EMW +LW GVP DEIP++ ITNGVHT TW++ + KL D YI
Sbjct: 360 RTSSYVNAVSKLHSKVTKEMWRHLWNGVPLDEIPVEGITNGVHTKTWLHNEIKKLVDRYI 419
Query: 426 GKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDI 485
G++WR++ LEG+WY +ERIPD ELWEAHLKAKRE IELI+RKI +RNERLGI+EPLP+I
Sbjct: 420 GRVWRDYAELEGLWYGVERIPDEELWEAHLKAKREFIELIKRKIKERNERLGIEEPLPEI 479
Query: 486 DENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
DENALIIGFARRFATYKRA L+ TDLERLK+IVNNPERPVYIIFGGKAHP DEAGKEFLR
Sbjct: 480 DENALIIGFARRFATYKRATLILTDLERLKKIVNNPERPVYIIFGGKAHPRDEAGKEFLR 539
Query: 546 RVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLNGVI 605
+VYEVSQMPEFK KI++ ENYDMGSAR +V+GVDVWLN PRRPLEASGTSGMKAGLNGV+
Sbjct: 540 KVYEVSQMPEFKNKIMVFENYDMGSARAMVAGVDVWLNNPRRPLEASGTSGMKAGLNGVL 599
Query: 606 NLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYENRSAW 665
NLSV+DGWWVEGYNG+NGWVIGD +LEPETE D+ DA SLY+LLEN V+P YYENR+ W
Sbjct: 600 NLSVYDGWWVEGYNGKNGWVIGDESLEPETEKDNIRDAQSLYNLLENEVIPTYYENRARW 659
Query: 666 IRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLSRDNFKWAKELAKWKEKIRRE 725
I MMKESI SIAPRFST+RMVKEY+ KFYS+A+ + L RD+FK +E+A WK KI
Sbjct: 660 IYMMKESIKSIAPRFSTHRMVKEYVDKFYSKALANAILLQRDSFKATREIASWKAKIFNS 719
Query: 726 WGEVEIEDAKVSEDS--IEVTLRLGNLRPEDVRVELYYGVKGDG-KIAEPSTVELRKMKE 782
W +VEIE ++ D+ +EV + L L PEDV+VE+YYGVK +G I +P +EL+ +
Sbjct: 720 WDKVEIERI-ITHDATGVEVIVNLDGLSPEDVKVEIYYGVKAEGYAIEKPYVIELKHPQS 778
Query: 783 LGDGRYVYSYSGKALKYINHDCWHYSVRVYAYHSMIPGKFLLGGYIKWK 831
LG R++Y Y G ALK + H CWHY+VRVY YH +P KFLL G IKWK
Sbjct: 779 LGGNRWLYRYEGNALKNLGHPCWHYAVRVYPYHDKLPHKFLL-GLIKWK 826
>emb|CAA04523.1| (AJ001088) alpha-glucan phosphorylase [Thermotoga maritima]
Length = 822
Score = 1031 bits (2638), Expect = 0.0
Identities = 491/825 (59%), Positives = 622/825 (74%), Gaps = 10/825 (1%)
Query: 11 ILRRLPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYKNPVKLLLEVPESRLRQL 70
+L +LPEN+ +L LAYN WWSW A +LW+ ID E W E++NPVK+L EV + RL +L
Sbjct: 1 MLEKLPENLKELESLAYNLWWSWSRPAQRLWRMIDSEKWEEHRNPVKILREVSKERLEEL 60
Query: 71 SRDDSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGKSLPIYSGGLG 130
S+D+ F+ LYEL +ERF +YM TW +NYP WD+ IVY+CMEYG+ K+LPIYSGGLG
Sbjct: 61 SKDEDFIALYELTLERFTDYMEREDTWFNVNYPEWDEKIVYMCMEYGLTKALPIYSGGLG 120
Query: 131 ILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQVLNND 190
ILAGDHLK+ASDLGLPLIA+GLLYKHGYF Q+ID DGRQIE FPEY+I +P++ + + D
Sbjct: 121 ILAGDHLKSASDLGLPLIAVGLLYKHGYFTQQIDSDGRQIEIFPEYDIEGLPMKPLRDED 180
Query: 191 GTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIK 250
G ++++VPI++ VKARVF V+VGRVKLYLLDTD EN + R+ICDYLYN EPD R+
Sbjct: 181 GNQVIVEVPIDNDTVKARVFEVQVGRVKLYLLDTDFEENEDRFRKICDYLYNPEPDVRVS 240
Query: 251 QEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEALELVRATSV 310
QEIL+GIGGM+LLK L+I+PGVIHLNEGHP+F++ ERI+ +ME+G +F EALE+VR T+V
Sbjct: 241 QEILLGIGGMKLLKTLKIKPGVIHLNEGHPAFSSLERIKSYMEEGYSFTEALEIVRQTTV 300
Query: 311 FTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFL-GLGKVTPEDTNFNMTVLSIRTSE 369
FTTHTPVPAGHD FP DFV +KL F + L LGK ED NFNMT L++RTS
Sbjct: 301 FTTHTPVPAGHDRFPFDFVEKKLTKFFEGFESKELLMNLGK--DEDGNFNMTYLALRTSS 358
Query: 370 FVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIW 429
F+N VSKLHA V+R M+ N+W GVP +EIPI+ ITNGVH TW+N + KL+D Y+G++W
Sbjct: 359 FINGVSKLHADVSRRMFKNVWKGVPVEEIPIEGITNGVHMGTWINREMRKLFDRYLGRVW 418
Query: 430 REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENA 489
REH +LEGIWY ++RIPD ELWEAHL AK+ I+ IR I +RNERLGI+EPLP+I EN
Sbjct: 419 REHTDLEGIWYGVDRIPDEELWEAHLNAKKRFIDYIRESIKRRNERLGINEPLPEISENV 478
Query: 490 LIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRVYE 549
LIIGFARRFATYKRA+LLF+DLERLKRIVNN ERPVYI++ GKAHP DE GKEFLRR+YE
Sbjct: 479 LIIGFARRFATYKRAVLLFSDLERLKRIVNNSERPVYIVYAGKAHPRDEGGKEFLRRIYE 538
Query: 550 VSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSV 609
VSQMP+FK KII++ENYD+G AR++VSGVDVWLN PRRP+EASGTSGMKA NGV+N SV
Sbjct: 539 VSQMPDFKNKIIVLENYDIGMARLMVSGVDVWLNNPRRPMEASGTSGMKAAANGVLNASV 598
Query: 610 FDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYENRSAWIRMM 669
+DGWWVEGYNGRNGWVIGD ++ PETEADD DA +LY+LLEN ++P YYENR WI MM
Sbjct: 599 YDGWWVEGYNGRNGWVIGDESVLPETEADDPKDAEALYELLENEIIPTYYENREKWIFMM 658
Query: 670 KESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLSRDNFKWAKELAKWKEKIRREWGEV 729
KESI + + KEY KFY + + +L R + +++ WKE+I + W V
Sbjct: 659 KESIKAWLQNSAPPACCKEYTEKFYIKGLVNREWLERR--ENVEKIGAWKERILKNWENV 716
Query: 730 EIEDAKVSED-SIEVTLRLGNLRPEDVRVELYYGVKGDG--KIAEPSTVELRKMKELGDG 786
IE + + S+EVT++LG+L P DV VEL G +G+G + + +R+ ++ +
Sbjct: 717 SIERIVLEDSKSVEVTVKLGDLTPNDVIVELVAG-RGEGMEDLEVWKVIHIRRYRKENES 775
Query: 787 RYVYSYSGKALKYINHDCWHYSVRVYAYHSMIPGKFLLGGYIKWK 831
++ + L ++ W Y+VRV YH +P KFL + WK
Sbjct: 776 IRLHLHQW-CLGHLGSPGWFYAVRVIPYHPRLPIKFLPEVPVVWK 819
>pir||D75304 probable alpha-glucan phosphorylase - Deinococcus radiodurans
(strain R1) >gi|6459995|gb|AAF11742.1|AE002052_5
(AE002052) alpha-glucan phosphorylase, putative
[Deinococcus radiodurans]
Length = 838
Score = 623 bits (1589), Expect = e-177
Identities = 316/775 (40%), Positives = 469/775 (59%), Gaps = 25/775 (3%)
Query: 8 KERILRRLPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYK-NPVKLLLEVPESR 66
K +L +LP I++L++LAYN +WSW +A L++ + E W ++ NPV+LLLE + R
Sbjct: 6 KVTVLPQLPAEIARLSELAYNLYWSWTPRAQALYRDLSPELWERFQHNPVRLLLEADQDR 65
Query: 67 LRQLSRDDSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGKSLPIYS 126
L ++D ++L Y V+ F+ YM TW + P+ KP+ Y MEY +SLPIYS
Sbjct: 66 LNAAAQDPAYLGRYAQVMADFDAYMGKKDTWAARHAPQM-KPVAYFSMEYAFHESLPIYS 124
Query: 127 GGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQV 186
GGLG+LAGDH K+ASDLGLP A+G+L+ GYF+Q D+DG Q E + E ++ +PI+
Sbjct: 125 GGLGVLAGDHCKSASDLGLPFTAVGMLFSQGYFRQLFDKDGWQNEAYDELDLTTLPIQPA 184
Query: 187 LNNDGTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPD 246
+ G + + V I R V +V+ ++VGRV++ LLD++VP+N EDDR++ LY +
Sbjct: 185 QSAAGEDIRVSVRIAGREVAVKVWTLQVGRVRVLLLDSNVPDNSEDDRKLTARLYGGNQE 244
Query: 247 KRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEALELVR 306
R++Q +L+G+ G+R L+AL++ V H+NEGH + ER+R ++ G F A EL
Sbjct: 245 LRVQQYVLLGVAGIRALRALDVPASVYHMNEGHAALMALERMREYVAAGQDFRTAAELAA 304
Query: 307 ATSVFTTHTPVPAGHDVFPVDFVREKLRLF--LRDLPQDKFLGLGKVTPEDTN-----FN 359
++++FTTHTPV AG+D F + + + + + L +D+ L + + F+
Sbjct: 305 SSTLFTTHTPVAAGNDAFTYELMDKYIGEWPGLLHAGRDELYALARHDQQWDGHTVPAFS 364
Query: 360 MTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAK 419
MTV ++ S N VS+LH +V+R MW+ L+PG +E+PI +TNG H T+ ++ +
Sbjct: 365 MTVFALSMSRAANGVSELHGEVSRGMWNFLYPGAEENEVPIGHVTNGAHNLTFTSQRMRD 424
Query: 420 LYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMK---RNERL 476
L + + W E + E +W A+E++ + +L + KRE+I +R ++ + RN
Sbjct: 425 LLSTVLPEDWTERLEDETMWQAVEQLTEEQLSNVQREMKREMITFVRGRVREQLLRNGAS 484
Query: 477 GIDEPLPD--IDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAH 534
D D +DE L IGFARRFATYKRA LL D RL IVNNPERPV +F GKAH
Sbjct: 485 AADVAATDNLLDEGTLTIGFARRFATYKRATLLLRDKPRLAAIVNNPERPVQFVFAGKAH 544
Query: 535 PMDEAGKEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
P D GK F++ +Y SQ PEF+GKI+++ENYDM AR LV GVD+WLN PRRPLEASGT
Sbjct: 545 PADNPGKAFIQEIYRTSQEPEFRGKIVILENYDMNVARHLVQGVDIWLNNPRRPLEASGT 604
Query: 595 SGMKAGLNGVINLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVV 654
SGMKA NG N SV DGWW EGY+G NGW IG+ + D DA LY LE+ +
Sbjct: 605 SGMKASFNGSPNFSVLDGWWREGYDGTNGWPIGEEREYADLNVQDDADAFDLYQRLEHEI 664
Query: 655 VPLYY---ENRSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLSRDNFKW 711
P YY + ++W ++++I +++PRFS R V +Y+ ++Y + G L+
Sbjct: 665 APRYYGHAQGNASWAHTVRDAIETVSPRFSMQRQVLDYVQQYYLPLGQRGTQLADHGGAR 724
Query: 712 AKELAKWKEKIRREWGEVEIE-------DAKVSED-SIEVTLRLGNLRPEDVRVE 758
A++LA WK +R++W I A+ E ++ + +RPE++RVE
Sbjct: 725 ARDLAAWKAWVRQQWPHTSISAQANLPATARPGEQVTVSAQVNPAGIRPEELRVE 779
>dbj|BAB11741.1| (AB047267) alpha-glucan phosphorylase [Thermus aquaticus]
Length = 819
Score = 584 bits (1489), Expect = e-165
Identities = 310/700 (44%), Positives = 439/700 (62%), Gaps = 29/700 (4%)
Query: 15 LPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYK-NPVKLLLEVPESRLRQLSRD 73
LPE + L ++AYN WWSW+ +A +L+Q +D W+ ++ NPVKLLLE+ +RL LS
Sbjct: 13 LPEPLEGLKEIAYNLWWSWNPEAAELFQELDPALWKRFRGNPVKLLLELDPARLEALSAS 72
Query: 74 DSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGKSLPIYSGGLGILA 133
+ + E Y+ A T + + Y EYG SLPIY+GGLG+LA
Sbjct: 73 -GYAARVQATREALRAYLEARRT-------KRGPLVAYFSAEYGFHSSLPIYAGGLGVLA 124
Query: 134 GDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQVLNNDGTP 193
GDH+K ASDLGL L+ +GL Y GYF Q + +G Q+E + E+P+ V + +G P
Sbjct: 125 GDHVKAASDLGLNLVGVGLFYHEGYFHQRLSPEGEQVEVYEPLRPEELPLVPVQDAEGRP 184
Query: 194 LLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQEI 253
+ + V R+V + V+VG V +YLL TD+PEN +DR+I LY A + RI+QE+
Sbjct: 185 VRVAVEFPGRLVHVGGYRVQVGAVPVYLLTTDLPENAPEDRQITARLYAAGLEARIQQEL 244
Query: 254 LIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEALELVRATSVFTT 313
++G+GG+R L+AL + P H+NEGH +F ER+R + +G F EALEL RA+++FTT
Sbjct: 245 VLGLGGVRFLRALGLAPAFFHMNEGHSAFLGLERLRELVAEGYPFREALELARASALFTT 304
Query: 314 HTPVPAGHDVFPVDFVREKLRLFLRDL--PQDKFLGLG-KVTPEDTNFNMTVLSIRTSEF 370
HTPVPAGHDVFP+D V L F L +D FLGLG + P F+M+ L++RT+
Sbjct: 305 HTPVPAGHDVFPLDLVDRYLGGFWEKLGVDRDTFLGLGLEEKPWGPVFSMSNLALRTAAQ 364
Query: 371 VNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWR 430
N VS+LH +V+R M+ +LWPG+ +E+PI +TNGVHT T+++ L + Y G W
Sbjct: 365 ANGVSRLHGEVSRNMFRHLWPGLLAEEVPIGHVTNGVHTWTFLHPRLRRHYAEVFGPEWV 424
Query: 431 EHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLG-----IDEPLPDI 485
E W +E + ++ W K ++ +R+++ ++ R G + E +
Sbjct: 425 ERPEDPETW-RVEGLGEA-FWRIRQDLKLFLVREVRQRLYEQRRRNGEGPARLREAEKAL 482
Query: 486 DENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
D AL IGFARRFATYKRA+LLF D ERL RI+ P PV +F GKAHP DEAGK +L+
Sbjct: 483 DPEALTIGFARRFATYKRAVLLFKDPERLLRILKGP-YPVQFVFAGKAHPKDEAGKAYLK 541
Query: 546 RVYEVSQMPEF--KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLNG 603
+ VS++ E+ + +++++E+YDM AR+L G DVWLNTPRRP+EASGTSGMKA LNG
Sbjct: 542 EL--VSKIREYGLEDRMVVLEDYDMYLARVLTHGSDVWLNTPRRPMEASGTSGMKAALNG 599
Query: 604 VINLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYEN-- 661
+NLSV DGWW E YNG+NG+ IGD + EA D DA +LYDLLE+ V+PL+Y
Sbjct: 600 ALNLSVLDGWWAEAYNGKNGFAIGDERVYESEEAQDVADAQALYDLLESEVIPLFYAKGL 659
Query: 662 ---RSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAM 698
S W+ M+ ES+ ++ P FS RMV++Y++ + A+
Sbjct: 660 EGYSSGWMSMVHESLRTVGPYFSAGRMVRDYLALYERGAL 699
>sp|O66932|PHSG_AQUAE GLYCOGEN PHOSPHORYLASE >gi|7514959|pir||H70362 glycogen
phosphorylase - Aquifex aeolicus
>gi|2983305|gb|AAC06896.1| (AE000704) glycogen
phosphorylase [Aquifex aeolicus]
Length = 692
Score = 564 bits (1438), Expect = e-159
Identities = 304/694 (43%), Positives = 439/694 (62%), Gaps = 30/694 (4%)
Query: 22 LADLAYNYWWSWDTKAMKLWQRIDEEHWREYK-NPVKLLLEVPESRLRQLSRDDSFLDLY 80
L +LAYN WW+W+ A +L++ ID W+E K NP++LL + L +D+ F+ +
Sbjct: 10 LWELAYNLWWTWNPPAKELFRSIDPLLWKETKENPIELLRKT--KLLENKLKDEDFISHF 67
Query: 81 ELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGKSLPIYSGGLGILAGDHLKTA 140
+ V ++ YM + + + KPIV+L EYG+ +L IY+GGLG LAGD LK +
Sbjct: 68 KYVYSLYKTYMNRHSKYEDT----YKKPIVFLSPEYGLHHTLLIYAGGLGFLAGDILKES 123
Query: 141 SDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQVLNNDGTPLLIDVPI 200
SDLG PLI +G +Y GY KQ I DG Q + + MP+++VL+ +G L V +
Sbjct: 124 SDLGFPLIGVGFMYPQGYVKQRIRVDGWQEDLDAQNQKELMPVKKVLDKEGKWLKCYVYV 183
Query: 201 EDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM 260
D V V+ V VG+ KLYLLDT+V EN +R I LY + D R++Q+I++G G +
Sbjct: 184 RDEKVYFGVWEVNVGKTKLYLLDTNVEENTPWNREISSRLYVPDKDLRLRQQIVLGFGTV 243
Query: 261 RLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEALELVRATSVFTTHTPVPAG 320
LL+ L I+ G H+NE +PSF I ++KGLT+++A+E VR S+FTTHTP+
Sbjct: 244 ILLEKLGIDAGGFHINEDYPSFVFLAEIFKLLKKGLTWDKAIEEVRKISLFTTHTPLRVA 303
Query: 321 HDVFPVDFVREKLRLFLRD---LPQDKFLGLGKVTPEDTN--FNMTVLSIRTSEFVNAVS 375
+ +P + E+ LF++D + K L LG PED + FN T++S+R +++VNAVS
Sbjct: 304 VNTYPFHMIEEQF-LFVKDVYGIDVKKVLELG-TNPEDPSEGFNSTIMSLRLAKYVNAVS 361
Query: 376 KLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREHVNL 435
K H +V+ +MWS L+ E PID +TNGVH PTW+ +L +LY+ Y+G+ + E +
Sbjct: 362 KRHQEVSSKMWSFLFK---EKENPIDYVTNGVHFPTWICSDLRRLYEEYLGENFVELHDH 418
Query: 436 EGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPD-----IDENAL 490
+ +W I IPD ELWE H++ K +IE I+ + +R + D + +D + L
Sbjct: 419 KSLWELIRDIPDEELWEYHIRNKERLIEHIKDRARERWVKEKADPSILMAEGLFLDSDVL 478
Query: 491 IIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRVYEV 550
+GFARR YKR L+FTD+ERLK+IVN+ ERPV IIF GKAHP D GK+ ++R++
Sbjct: 479 TVGFARRMTGYKRPDLIFTDVERLKKIVNDSERPVQIIFAGKAHPADIEGKKIIQRIFNF 538
Query: 551 SQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVF 610
++ PEF G+I +E+YD A +V GVDVWLN P PLEA GTSGMKA +NGV++LS+
Sbjct: 539 AKDPEFGGRIAFVEDYDELLAHYMVRGVDVWLNNPLPPLEACGTSGMKASMNGVLHLSIL 598
Query: 611 DGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYDLLENVVVPLYYENRS-----AW 665
DGWW+EGYNG+NGW GD +E + + DA ++Y++LEN V+PLYYE W
Sbjct: 599 DGWWIEGYNGKNGWAFGDYEVEGDR---NRADAEAIYNILENEVIPLYYERDERGVPVKW 655
Query: 666 IRMMKESIMSIAPRFSTYRMVKEYISKFYSRAME 699
I MMKE+I SI P F + RM+K+YI+KFYS+ ++
Sbjct: 656 ISMMKEAIKSITPNFCSRRMLKDYINKFYSKILK 689
>sp|Q10639|PHSG_MYCTU GLYCOGEN PHOSPHORYLASE >gi|7478100|pir||D70770 probable glycogen
phosphorylase - Mycobacterium tuberculosis (strain
H37RV) >gi|1340094|emb|CAA98092.1| (Z73902) glgP
[Mycobacterium tuberculosis]
Length = 863
Score = 550 bits (1403), Expect = e-155
Identities = 316/853 (37%), Positives = 472/853 (55%), Gaps = 49/853 (5%)
Query: 15 LPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREY-KNPVKLLLEVPESRLRQLSRD 73
LPE ++ L L+ N WSWD L+ ID W + +PV LL V +RL +L+ D
Sbjct: 13 LPERLAALDQLSTNLRWSWDKPTQDLFAAIDPALWEQCGHDPVALLGAVNPARLDELALD 72
Query: 74 DSFLDLYELVIERFENYMRATTTWMTMN-----YPRWDKPIVYLCMEYGIGKSLPIYSGG 128
FL + + +Y+ + I Y +E+G+ + LP YSGG
Sbjct: 73 AEFLGALDELAADLNDYLSRPLWYQEQQDAGVAAQALPTGIAYFSLEFGVAEVLPNYSGG 132
Query: 129 LGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQVLN 188
LGILAGDHLK+ASDLG+PLIA+GL Y+ GYF+Q + DG Q E +P + + +P+R + +
Sbjct: 133 LGILAGDHLKSASDLGVPLIAVGLYYRSGYFRQSLTADGWQHETYPSLDPQGLPLRLLTD 192
Query: 189 NDGTPLLIDVPIEDR-IVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPDK 247
+G P+L++V + D +++AR+++ +VGRV L LLD+D+PEN D R + D LY + +
Sbjct: 193 ANGDPVLVEVALGDNAVLRARIWVAQVGRVPLLLLDSDIPENEHDLRNVTDRLYGGDQEH 252
Query: 248 RIKQEILIGIGGMRLLKALEI-----EPGVIHLNEGHPSFANFERIRWFM-EKGLTFEEA 301
RIKQEIL GIGG+R ++A P V H+NEGH F ERIR + + GL F+ A
Sbjct: 253 RIKQEILAGIGGVRAIRAYTAVEKLTPPEVFHMNEGHAGFLGIERIRELVTDAGLDFDTA 312
Query: 302 LELVRATSVFTTHTPVPAGHDVFPVDFVREKLR--------LFLRDLPQDKFLGLGKVTP 353
L +VR+++VFTTHTPVPAG D FP++ V+ + L LP D+ + LG
Sbjct: 313 LTVVRSSTVFTTHTPVPAGIDRFPLEMVQRYVNDQRGDGRSRLLPGLPADRIVALG-AED 371
Query: 354 EDTNFNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWV 413
+ FNM + +R ++ N VS LH +V+R M++ LW G DE+PI ++TNGVH PTW
Sbjct: 372 DPAKFNMAHMGLRLAQRANGVSLLHGRVSRAMFNELWAGFDPDEVPIGSVTNGVHAPTWA 431
Query: 414 NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKR- 472
+L G + + +W + ++ + LW + + ++E +R ++ +
Sbjct: 432 APQWLQLGRELAGS---DSLREPVVWQRLHQVDPAHLWWIRSQLRSMLVEDVRARLRQSW 488
Query: 473 NERLGIDEPLPDI----DENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYII 528
ER D L I D N L +GFARR TYKR L+ D +RL++++ + +RP+ +I
Sbjct: 489 LERGATDAELGWIATAFDPNVLTVGFARRVPTYKRLTLMLRDPDRLEQLLLDEQRPIQLI 548
Query: 529 FGGKAHPMDEAGKEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRP 588
GK+HP D+ GK +++V + P+ + +I + NYDM AR+L G DVWLN P RP
Sbjct: 549 VAGKSHPADDGGKALIQQVVRFADRPQVRHRIAFLPNYDMSMARLLYWGCDVWLNNPLRP 608
Query: 589 LEASGTSGMKAGLNGVINLSVFDGWWVEGYNGRNGWVIGDATLEPETEADDYLDAMSLYD 648
LEA GTSGMK+ LNG +NLS+ DGWW E Y+G NGW I A + D L+A +LYD
Sbjct: 609 LEACGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADENRRDDLEAGALYD 668
Query: 649 LLENVVVPLYYEN-----RSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVY 703
LL V P +YE W+ M++ ++ ++ P+ RMV++Y+ +Y+ A ++
Sbjct: 669 LLAQAVAPKFYERDERGVPQRWVEMVRHTLQTLGPKVLASRMVRDYVEHYYAPAAQSFRR 728
Query: 704 LSRDNFKWAKELAKWKEKIRREWGEVEIEDAKV----------SEDSIEVTLRLGNLRPE 753
+ F A+ELA ++ + W ++EI D S+ ++ T+RL LRP
Sbjct: 729 TAGAQFDAARELADYRRRAEEAWPKIEIADVDSTGLPDTPLLGSQLTLTATVRLAGLRPN 788
Query: 754 DVRVELYYG-VKGDGKIAEPSTVELRKMKELGDGRYVYSYSGKALKYINHDCWHYSVRVY 812
DV V+ G V + +P TVE+ GDG Y + L Y+VRV
Sbjct: 789 DVTVQGVLGRVDAGDVLMDPVTVEMAH-TGTGDGGYEIFSTTTPLPLAGP--VGYTVRVL 845
Query: 813 AYHSMIPGKFLLG 825
H M+ LG
Sbjct: 846 PRHPMLAASNELG 858
>emb|CAB40105.1| (AJ001205) putative glycogen phosphorylase [Streptomyces coelicolor
A3(2)]
Length = 872
Score = 536 bits (1366), Expect = e-151
Identities = 318/846 (37%), Positives = 462/846 (54%), Gaps = 53/846 (6%)
Query: 15 LPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYK-NPVKLLLEVPESRLRQLSRD 73
LP+ + L+DLA N WSW + L+ +D E W +PV+LL V +RL +L+ D
Sbjct: 13 LPDPLRPLSDLARNLRWSWHPETRDLFHSVDPECWTASGGDPVRLLGTVRPARLAELAED 72
Query: 74 DSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGKSLPIYSGGLGILA 133
FL V ++YM W R + Y E+GI +LP YSGGLGILA
Sbjct: 73 RRFLRRLTAVAYDLDHYMTGDR-WYQAQSGRLPAAVAYFSPEFGITAALPQYSGGLGILA 131
Query: 134 GDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQVLNNDGTP 193
GDHLK ASDLG+PL+ +GLLY+HGYF+Q + RDG Q E +P + E+P+ + DGTP
Sbjct: 132 GDHLKAASDLGVPLVGVGLLYRHGYFRQSLSRDGWQQEHYPVLDPHELPLAPLKERDGTP 191
Query: 194 LLIDVPIED-RIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQE 252
+ + + R ++ARV+L +VGRV L LLD+DV EN +R + D LY + R+ QE
Sbjct: 192 AHVALALPGGRELRARVWLAQVGRVPLLLLDSDVEENDPGERGVTDRLYGGGSEHRLLQE 251
Query: 253 ILIGIGGMRLLKAL-----EIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEALELVRA 307
+L+GIGG+R ++ P V H NEGH F ERI + G F ALE VRA
Sbjct: 252 MLLGIGGVRAVRTYCRITGHPAPEVFHTNEGHAGFLGLERIAELCDAGSDFGSALEAVRA 311
Query: 308 TSVFTTHTPVPAGHDVFPVDFVREKLR--LFLRDLPQDKFLGLGKVT---PEDTNFNMTV 362
+VFTTHTPVPAG D F + V L + ++ L LG T E FNM V
Sbjct: 312 GTVFTTHTPVPAGIDRFDRELVARHFGPDAELPRIEVERVLRLGMETYPGGEPNLFNMAV 371
Query: 363 LSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYD 422
+ +R ++ N VS LH V+R M++ LWPG DE+PI ++TNGVH PTWV + +L
Sbjct: 372 MGLRLAQRANGVSVLHGGVSRGMFAGLWPGFDADEVPITSVTNGVHAPTWVAPEVFRLGA 431
Query: 423 IYIGKIWREHVNLEG---IWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLG-- 477
IG E G W ++ IPD ++WE + +++E +R ++ + G
Sbjct: 432 RQIGVQRAEDALAVGGSDRWDSVADIPDRDIWELRRTLRAQLVEEVRERLRASWRQRGAG 491
Query: 478 ------IDEPLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGG 531
ID+ L D + L IGFARR +YKR L+ D ERL ++ +PERP+ I+ G
Sbjct: 492 TAELGWIDDAL---DPDVLTIGFARRVPSYKRLTLMLRDRERLTELLLHPERPIQIVVAG 548
Query: 532 KAHPMDEAGKEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEA 591
KAHP D+ GK ++ + + + +I+ + +Y M A+ L G D+WLN P RPLEA
Sbjct: 549 KAHPADDGGKRLVQELVRFADDARVRHRIVFLPDYGMAMAQKLYPGCDIWLNNPLRPLEA 608
Query: 592 SGTSGMKAGLNGVINLSVFDGWWVEGYNGRNGWVIGDAT-LEPETEADDYLDAMSLYDLL 650
GTSGMKA LNG +NLSV DGWW E Y GW I A + + D ++A +LYDLL
Sbjct: 609 CGTSGMKAALNGCLNLSVLDGWWDEWYQPDFGWAIPTADGAGTDPDRRDAIEADALYDLL 668
Query: 651 ENVVVPLYYENRSA-----WIRMMKESIMSIAPRFSTYRMVKEYISKFYSRAMETGVYLS 705
E + P +YE ++ W+ M++ ++ + P+ RMV+EY+ + Y+ A E +
Sbjct: 669 EQRITPRFYERGASGLPDRWLEMVRRTLSLLGPKVLAGRMVREYVERLYTPAAEAHRAMD 728
Query: 706 RDNFKWAKELAKWKEKIRREWGEVEIEDAKVSED----------SIEVTLRLGNLRPEDV 755
D+ A+ LA+WK ++R W V ++ + S ++ V ++LG+L PEDV
Sbjct: 729 PDS---ARGLAEWKARVRAAWPGVSVDHVETSAATASAELGTTLALRVRVKLGDLAPEDV 785
Query: 756 RVELYYG-VKGDGKIAEPSTVELRKM--KELGDGRYVYSYSGKALKYINHDCWHYSVRVY 812
V+ G V + +I + + L+ + +L +GR+ Y L + Y+VRV
Sbjct: 786 EVQAVSGRVDSEDRITDAARTSLKPVGGPDL-EGRWAYE---GPLALDRTGPFGYTVRVL 841
Query: 813 AYHSMI 818
H ++
Sbjct: 842 PAHRLL 847
>emb|CAB72420.1| (AL138978) putative glycogen phosphorylase [Streptomyces coelicolor
A3(2)]
Length = 705
Score = 488 bits (1244), Expect = e-137
Identities = 277/694 (39%), Positives = 389/694 (55%), Gaps = 33/694 (4%)
Query: 15 LPENISKLADLAYNYWWSWDTKAMKLWQRIDEEHWREYK-NPVKLLLEVPESRLRQLSRD 73
LP+ + L+DLA N WSW + L+ +D E W +PV+LL V +RL +L+ D
Sbjct: 15 LPDPLRPLSDLARNLRWSWHPETRDLFHSVDPECWTASGGDPVRLLGTVRPARLAELAED 74
Query: 74 DSFLDLYELVIERFENYMRATTTWMTMNYPRWDKPIVYLCMEYGIGKSLPIYSGGLGILA 133
FL V ++YM W R + Y E+GI +LP YSGGLGILA
Sbjct: 75 RRFLRRLTAVAYDLDHYMTGDR-WYQAQSGRLPAAVAYFSPEFGITAALPQYSGGLGILA 133
Query: 134 GDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQVLNNDGTP 193
GDHLK ASDLG+PL+ +GLLY+HGYF+Q + RDG Q E +P + E+P+ + DGTP
Sbjct: 134 GDHLKAASDLGVPLVGVGLLYRHGYFRQSLSRDGWQQEHYPVLDPHELPLAPLKERDGTP 193
Query: 194 LLIDVPIED-RIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQE 252
+ + + R ++ARV+L +VGRV L LLD+DV EN +R + D LY + R+ QE
Sbjct: 194 AHVALALPGGRELRARVWLAQVGRVPLLLLDSDVEENDPGERGVTDRLYGGGSEHRLLQE 253
Query: 253 ILIGIGGMRLLKAL-----EIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEALELVRA 307
+L+GIGG+R ++ P V H NEGH F ERI + G F ALE VRA
Sbjct: 254 MLLGIGGVRAVRTYCRITGHPAPEVFHTNEGHAGFLGLERIAELCDAGSDFGSALEAVRA 313
Query: 308 TSVFTTHTPVPAGHDVFPVDFVREKLR--LFLRDLPQDKFLGLGKVT---PEDTNFNMTV 362
+VFTTHTPVPAG D F + V L + ++ L LG T E FNM V
Sbjct: 314 GTVFTTHTPVPAGIDRFDRELVARHFGPDAELPRIEVERVLRLGMETYPGGEPNLFNMAV 373
Query: 363 LSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYD 422
+ +R ++ N VS LH V+R M++ LWPG DE+PI ++TNGVH PTWV + +L
Sbjct: 374 MGLRLAQRANGVSVLHGGVSRGMFAGLWPGFDADEVPITSVTNGVHAPTWVAPEVFRLGA 433
Query: 423 IYIGKIWREHVNLEG---IWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLG-- 477
IG E G W ++ IPD ++WE + +++E +R ++ + G
Sbjct: 434 RQIGVQRAEDALAVGGSDRWDSVADIPDRDIWELRRTLRAQLVEEVRERLRASWRQRGAG 493
Query: 478 ------IDEPLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGG 531
ID+ L D + L IGFARR +YKR L+ D ERL ++ +PERP+ I+ G
Sbjct: 494 TAELGWIDDAL---DPDVLTIGFARRVPSYKRLTLMLRDRERLTELLLHPERPIQIVVAG 550
Query: 532 KAHPMDEAGKEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEA 591
KAHP D+ GK ++ + + + +I+ + +Y M A+ L G D+WLN P RPLEA
Sbjct: 551 KAHPADDGGKRLVQELVRFADDARVRHRIVFLPDYGMAMAQKLYPGCDIWLNNPLRPLEA 610
Query: 592 SGTSGMKAGLNGVINLSVFDGWWVEGYNGRNGWVIGDAT-LEPETEADDYLDAMSLYDLL 650
GTSGMKA LNG +NLSV DGWW E Y GW I A + + D ++A +LYDLL
Sbjct: 611 CGTSGMKAALNGCLNLSVLDGWWDEWYQPDFGWAIPTADGAGTDPDRRDAIEADALYDLL 670
Query: 651 ENVVVPLYYENRSA-----WIRMMKESIMSIAPR 679
E + P +YE ++ W+ M++ ++ + P+
Sbjct: 671 EQRITPRFYERGASGLPDRWLEMVRRTLSLLGPK 704
>sp|Q59025|YG31_METJA HYPOTHETICAL PROTEIN MJ1631 >gi|2128981|pir||E64503 hypothetical
protein MJ1631 - Methanococcus jannaschii
>gi|1500530|gb|AAB99652.1| (U67603) glycogen
phosphorylase (glgP) [Methanococcus jannaschii]
Length = 519
Score = 237 bits (598), Expect = 4e-61
Identities = 187/598 (31%), Positives = 279/598 (46%), Gaps = 91/598 (15%)
Query: 107 KPIVYLCMEYGIGKSLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRD 166
KP Y CME+ I + L Y+GGLG LAG H + A L PL+ + +L+ +GY+ Q DR+
Sbjct: 2 KPTAYFCMEFAIHQPLKTYAGGLGFLAGSHFRAAKRLNQPLVGVSILWSYGYYDQLRDRE 61
Query: 167 GR-QIEKFPEYNIREMPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVE---VGRVKLYLL 222
G+ ++E +Y I+ L + V I + V + + +E G +Y L
Sbjct: 62 GKMKVEYIRKYYDFLEDIK---------LKVPVTINNNTVWVKAYKLEEDVFGTCPIYFL 112
Query: 223 DTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSF 282
TD+PEN + R I LY+A I Q+I++GIGG +++K E + H+NE HP
Sbjct: 113 TTDIPENDDFSRTITHNLYDANNILHIAQQIVLGIGGYKVIKECE-NVKLFHMNEPHPLP 171
Query: 283 ANFERIRWFMEKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQ 342
F+ I E LE R +VFTTHTP+P G++ ++ ++ D+
Sbjct: 172 LVFKLIE---------EYGLEYTREHTVFTTHTPLPEGNETQDINLLKSMGFFGNVDVKL 222
Query: 343 DKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDA 402
+ LG FN TV ++R + NAVSK H +V MWS W D I A
Sbjct: 223 AEKLG-------GNPFNYTVCALRVCKRANAVSKKHKEVCDRMWS--W---VKDRCEIVA 270
Query: 403 ITNGVHTPTW---VNENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKR 459
ITN W V AK YDI + RE K
Sbjct: 271 ITNAQDKYYWQDPVIREAAKKYDI---DMLRER-------------------------KM 302
Query: 460 EVIELIRRKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVN 519
E+ E++ ++ + ++ ++ L + +ARRF YKR +L D RL ++
Sbjct: 303 ELKEILFEEVADQTGKI--------FKKDRLTVVWARRFTAYKRPHILLHDEMRLLELLK 354
Query: 520 NPERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVD 579
++ + +I+ GK HP D + VS+ + KG IL Y++ +++L G D
Sbjct: 355 --KKRIQVIWAGKPHPNDH--NMIATFNWIVSKTRDMKGATIL-TGYELKLSKMLKQGSD 409
Query: 580 VWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGW---WVEGYNGRNGWVIGDATLEPETE 636
+WLNTP+ EASGTSGM A +N I++S DGW W + Y + + IGD +
Sbjct: 410 IWLNTPKLNHEASGTSGMTASMNASIHMSTLDGWHVEWAKMYPD-DSFTIGDGVRD---- 464
Query: 637 ADDYLDAMSLYDLLENVVVPLYYENRSAWIRMMKESIMSIAPRFSTYRMVKEYISKFY 694
DD A +Y+LLE V Y+ W++ + I F RM KEY K Y
Sbjct: 465 -DDAYVANCIYNLLEEVAD--MYDTERWWMKAC-NCVNHIVEYFDAERMAKEYAEKLY 518
>gb|AAK42667.1| Glucan phosphorylase, putative (glgP or malP) [Sulfolobus
solfataricus]
Length = 465
Score = 106 bits (262), Expect = 1e-21
Identities = 122/511 (23%), Positives = 205/511 (39%), Gaps = 127/511 (24%)
Query: 125 YSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIR 184
++GGLGIL GD A+ LG+ I LLY+ GY D +G+Q R
Sbjct: 17 FAGGLGILEGDKFYAAARLGINYTVITLLYRRGY----ADGEGKQ--------------R 58
Query: 185 QVLNNDGTPLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPENREDDRRICDYLYNAE 244
++L++ ++ + D+ + + K+ + P N + ++ Y+ N+
Sbjct: 59 ELLSHLNKEWENEITVGDQRIMVEYLAYTLNTAKVIFAN---PLNTNLNDQL--YVENSN 113
Query: 245 PDKRIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFMEKGLTFEEA--- 301
++ K +L + E + S ERI W K + +EA
Sbjct: 114 DERFYKCLLLAKVA------------------ENYIS----ERIGWDKVKFVDMQEACPA 151
Query: 302 -LELVRATSVF--TTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVTPEDTNF 358
L L+R + HTP P GH FP +++ F + P D V D
Sbjct: 152 FLPLLRYFPRYRIVVHTPAPWGHPTFPSHLFKKE---FSFEFPLDH------VVMTDIGL 202
Query: 359 NMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLA 418
+ ++ I V+++M ++ P I A+TNG+ W N +L
Sbjct: 203 SASIEGI--------------VVSKKMLKHVSRTFPQHMHKIRAVTNGIEISRWRNPSLN 248
Query: 419 KLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGI 478
+ D+ + + ++ KR+ I ++LG
Sbjct: 249 MVKDL------------------------DDFMKKRIEVKRDSI-----------KKLGK 273
Query: 479 DEPLPDIDENALIIGFARRFATYKRAILLFTDLERLKRIVNNPERPVYIIFGGKAHPMDE 538
D P I + RR YKR + + R++++ + V+ I GG AHP D
Sbjct: 274 DTDKP-------TIAWLRRITGYKRP-------DFILRLIDDLKDDVFFIIGGLAHPKDY 319
Query: 539 AGKEFLRRVYEVSQMPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMK 598
+ E R+ E+S + + +I I D ++ + D+W TP EASGTS MK
Sbjct: 320 SAVEIERKFKEIS---DKRNNVIYIRGADANFMKLAIWASDIWTFTPYSGWEASGTSFMK 376
Query: 599 AGLNGVINLSVFDGWWVEGYN-GRNGWVIGD 628
AG+NG+ +++ DG E N G NGW+ G+
Sbjct: 377 AGINGIPSVASRDGAVTEIINDGYNGWLYGE 407
>sp|P45180|PHSG_HAEIN GLYCOGEN PHOSPHORYLASE >gi|1073835|pir||D64119 glycogen
phosphorylase (EC 2.4.1.1) - Haemophilus influenzae
(strain Rd KW20) >gi|1574824|gb|AAC23008.1| (U32815)
glycogen phosphorylase (glgP) [Haemophilus influenzae
Rd]
Length = 821
Score = 103 bits (255), Expect = 7e-21
Identities = 138/576 (23%), Positives = 243/576 (41%), Gaps = 103/576 (17%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQ------EIDRDGRQIEKFPEYNIR 179
+GGLG LA + + + LGLP + G+ Y++G F+Q +++R +EK +
Sbjct: 128 NGGLGRLAACFMDSIATLGLPGMGYGIRYEYGMFRQKIENGQQVERPDAWLEKGAPWEFI 187
Query: 180 EMPIRQVLNNDG-----------------TPLLIDVPI----EDRIVKARVFLVEVGRVK 218
R + G T L D I + R++ G V
Sbjct: 188 RPSKRFTVEFGGNIHFEGKKCIWQDTEKVTALAYDQMIPGYQNNSAATLRLWSAHAGEV- 246
Query: 219 LYLLDTD------VPENREDDRRICDYLYNAEP-----DKRIKQEILIGIGGM------- 260
L D + E ++ + LY + + R++QE + +
Sbjct: 247 FNLADFNRGEHLAALEEHSANKNLSRVLYPDDSTWNGRELRLRQEYFLVSASLQDILRRH 306
Query: 261 -RLLKALE--IEPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTP 316
R +LE + IHLN+ HP+ A E +R ++ +G +++A E+ R +T HT
Sbjct: 307 KRTHNSLENLADKVAIHLNDTHPALAIPELMRILVDDEGFEWKKAWEMTRNIFSYTCHTL 366
Query: 317 VPAGHDVFPVDFVREKLRLFLRDLPQ--DKFLGLGKV-TPEDTNF--------------- 358
+ + +PV+ + + L L+ + + D FL + D +F
Sbjct: 367 MSEALETWPVEMMAKILPRHLQMIFEINDHFLEYVRTYVTTDNDFIRRVSLIEEGYQRKV 426
Query: 359 NMTVLSIRTSEFVNAVSKLHAKV----TREMWSNLWPGVPTDEIPIDAITNGVHTPTWV- 413
M LS+ S +N V+++H+ + T ++ ++P T+ +TNG+ W+
Sbjct: 427 RMGWLSVVGSHKINGVAEIHSDLMVTSTFADFARIFPERFTN------VTNGITPRRWLA 480
Query: 414 --NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMK 471
N LA L+D YIG WR ++ IE++ +A +A ++ + K+ +
Sbjct: 481 VANPQLAALFDKYIGSEWRCDLS------QIEKLKPFAQEKAFKEAVADIKFANKVKLAE 534
Query: 472 R-NERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVY 526
LG++ +D +AL +R YKR +L + + R ++ NPE+ P
Sbjct: 535 YVKSELGVE-----LDPHALFDVQVKRIHEYKRQMLNVLHIIARYNEMLTNPEKDWQPRV 589
Query: 527 IIFGGKAHPMDEAGKEFLRRVYEVSQM----PEFKG--KIILIENYDMGSARILVSGVDV 580
I GKA A K+ + + +V+ + KG K++ I NY + A++++ D+
Sbjct: 590 FILAGKAASAYYAAKQTIHLINDVANVINNDERLKGRLKVVFIPNYSVSLAQLIIPAADI 649
Query: 581 WLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
EASGTS MK LNG + L DG VE
Sbjct: 650 SEQISLAGTEASGTSNMKFALNGALTLGTLDGANVE 685
>pir||T45633 starch phosphorylase (EC 2.4.1.1) H, cytosolic F13I12.20
[similarity] - Arabidopsis thaliana
>gi|6522578|emb|CAB61943.1| (AL133292) starch
phosphorylase H (cytosolic form)-like protein
[Arabidopsis thaliana]
Length = 841
Score = 102 bits (251), Expect = 2e-20
Identities = 143/595 (24%), Positives = 246/595 (41%), Gaps = 117/595 (19%)
Query: 120 KSLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQ------IEKF 173
K + +GGLG LA L + + L LP GL Y+HG FKQ I + G++ +EKF
Sbjct: 130 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKF 189
Query: 174 PEYNIRE----MPIRQV----LNNDGT----------PLLIDVPIEDRIVKARVFLVEVG 215
+ I P+R +N DG+ L DVPI K + L +
Sbjct: 190 SPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISL-RLW 248
Query: 216 RVKLYLLDTDVPENREDD-----------RRICDYLYNAEPDK-----RIKQEILIGIGG 259
K D D+ + E + ++IC LY + + R+KQ+ +
Sbjct: 249 EAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSAS 308
Query: 260 MRLL--------------KALEIEPGV-IHLNEGHPSFANFERIRWFME-KGLTFEEALE 303
++ + K E V + +N+ HP+ A E +R M+ GL ++EA +
Sbjct: 309 LQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWD 368
Query: 304 LVRATSVFTTHTPVPAGHDVFP-----------VDFVREKLRLFLRDLP------QDKFL 346
+ T +T HT +P + + ++ + E + F++ + +DK
Sbjct: 369 VTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKIS 428
Query: 347 GLGKV--TPEDTNFNMTVLSIRTSEFVNAVSKLHAKVTR-EMWSN---LWPGVPTDEIPI 400
L + P+ M L + +S VN V++LH+ + + E++++ +WP ++
Sbjct: 429 SLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNK--- 485
Query: 401 DAITNGVHTPTWVNENLAKLYDIYIGKI----WREHVNL-EGI-WYAIERIPDSELWEAH 454
TNG+ W+ +L DI + W ++L G+ +A SE A
Sbjct: 486 ---TNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAK 542
Query: 455 LKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL-------L 507
K+ + + I R G+ ID +L +R YKR ++
Sbjct: 543 TANKKRLAQYIERVT-------GVS-----IDPTSLFDIQVKRIHEYKRQLMNILGVVYR 590
Query: 508 FTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQM----PEFKG--KII 561
F L+ +K P ++ GGKA K ++ V +V + PE K++
Sbjct: 591 FKKLKEMKPEERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVV 650
Query: 562 LIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
+ NY++ A +L+ G ++ + +EASGTS MK LNG + + DG VE
Sbjct: 651 FVPNYNVTVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVE 705
>gb|AAF39800.1| (AC006636) contains similarity to Pfam domain PF00343
(phosphorylase), Score=1562.5, E-value=0, N=1
[Caenorhabditis elegans]
Length = 882
Score = 101 bits (250), Expect = 3e-20
Identities = 143/582 (24%), Positives = 232/582 (39%), Gaps = 104/582 (17%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEK------------- 172
+GGLG LA L + + LG+P GL Y++G FKQ I RDG QIE+
Sbjct: 168 NGGLGRLAACFLDSMATLGIPAYGYGLRYEYGIFKQLI-RDGWQIEEPDDWLRFGNPWEK 226
Query: 173 -FPEYNIREMPIRQVLNNDGTPLLID------VPIEDRIVKARVFLVEVGRV-------- 217
PEY + +V+ DG ID +P + + + +V R+
Sbjct: 227 ARPEYMLPVNFYGKVVKEDGKSKWIDTQVVFAMPYDTPVPGYKNNIVNTLRLWSAKAENH 286
Query: 218 --KLYLLDTDVPE---NREDDRRICDYLYNAE-----PDKRIKQEILI------------ 255
+ D D + +R I LY + + R+KQ+ +
Sbjct: 287 FHLKFFNDGDYVQAVMDRNLSENITRVLYPNDNMFLGKELRLKQQYFLVAATLQDIIRRF 346
Query: 256 --GIGGMRLLKALEIEPG----VIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRAT 308
I G R + E I LN+ HPS E IR ++ +GLT+++A ++ T
Sbjct: 347 KSSIYGNREAVRVNFETFPDKVAIQLNDTHPSIGIPELIRLLIDVEGLTWDQAWDICIKT 406
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKL-----------RLFLRDLPQ------DKFLGLGKV 351
+T HT +P + +PV ++ L + F+ + Q D+ + V
Sbjct: 407 YAYTNHTLLPEALERWPVSLMQNLLPRHLEIIYEINQKFMNTISQRFPGDFDRMRRMSIV 466
Query: 352 TPEDT----NFNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGV 407
D NM L I S +N V+ LH+ + + + D TNG+
Sbjct: 467 EEADQFGEKRINMAHLCIVASHAINGVAALHSDLLKSSTFRDFYEFYPDRFQNK--TNGI 524
Query: 408 HTPTWV---NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIEL 464
W+ N +LA L IG+ W NL+ + E D+ ++ + K E +
Sbjct: 525 TPRRWLLLSNPSLADLIVEKIGESWI--TNLDELQKLKEYANDAGFLDSIRRVKLENKQQ 582
Query: 465 IRRKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAILLFTDLERL-KRIVNNPER 523
+ + + DE +++ +L +R YKR +L + L RI NP
Sbjct: 583 VAQYLS--------DEYNVNVNAASLFDVHVKRIHEYKRQLLNILHVIALYNRIKENPNI 634
Query: 524 PVY---IIFGGKAHPMDEAGKEFLRRVYEVSQMPEFKG------KIILIENYDMGSARIL 574
+ +++GGKA P K+ +R + V++ K+I +ENY + A +
Sbjct: 635 DMVKRTVLYGGKAAPGYHMAKQIIRLITAVAEQVNNDAIVGDRLKVIFLENYRVSMAEKI 694
Query: 575 VSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
+ D+ EASGT MK LNG + + DG VE
Sbjct: 695 IPASDLSEQISTAGTEASGTGNMKFMLNGALTIGTLDGANVE 736
>dbj|BAB04803.1| (AP001510) glycogen phosphorylase [Bacillus halodurans]
Length = 815
Score = 100 bits (246), Expect = 8e-20
Identities = 143/575 (24%), Positives = 238/575 (40%), Gaps = 99/575 (17%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQ 185
+G LG LA L + + L LP G+ YK+G F+Q+I DG Q+E P+Y ++ + +
Sbjct: 114 NGDLGRLAACFLDSLASLELPGHGCGIRYKYGLFQQKIV-DGNQVE-LPDYWLKNEYVWE 171
Query: 186 VLNNDGT-PLLIDVPIEDRIVKARVFLVEVGRVKLYLLDTDVPEN--------------- 229
D T + IE R+ K+ + D+P +
Sbjct: 172 TKRLDQTVEVHFGGEIETVEESGRLTFKHHHYEKVLAVPYDIPVSGYQNHTVNTLRLWSA 231
Query: 230 -------------REDDRRICDYLYNAE-------PDK--------RIKQEILIGIGGMR 261
R+D DY + E PD R+KQ+ + G++
Sbjct: 232 ESTTNDFHFYSIDRKDYYHYLDYKRSVEQISEFLYPDDSSYEGRLLRLKQQYFLVSAGLQ 291
Query: 262 LL--------KALEIEPG--VIHLNEGHPSFANFERIRWFMEKG-LTFEEALELVRATSV 310
+ ++++ P I +N+ HPS E +R +++ L++E+A EL T
Sbjct: 292 CILREFKNSYPSVDLLPEKIAIQINDTHPSLVIPELMRLLLDQEQLSWEKAWELTTRTVA 351
Query: 311 FTTHTPVPAGHDVFPVDFVRE---KLRLFLRDLPQD--KFLGLGKVTPEDTNFNMTVLS- 364
+T HT + + +PVD V+ ++ + + ++ + + L L T D +M ++S
Sbjct: 352 YTNHTTMSEALETWPVDMVKTLLPRIYMIIHEINERFCRHLWLAHPTLRDEIKHMAIISY 411
Query: 365 ---------IRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWV-- 413
I S VN V+KLH + + S + P + TNG+ W+
Sbjct: 412 GQIHMAHLAIVGSYSVNGVAKLHTDILKN--SVMKPFYTVFPEKFNNKTNGITHRRWLLM 469
Query: 414 -NENLAKLYDIYIGKIW-REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMK 471
N LA L IG+ W RE L + ++ D+ E K+ + + I
Sbjct: 470 ANPPLASLITEAIGETWVREPKQLITL---LKYAGDAAFQEKIAGVKQANKTALAKYIQ- 525
Query: 472 RNERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYI 527
ER GI +D+ ++ +R YKR +L +F L + I +NP P
Sbjct: 526 --ERTGIR-----VDDRSIFDVHIKRLHGYKRQLLNVFHILHLYEMIRDNPNMDMVPRTF 578
Query: 528 IFGGKAHPMDEAGKEFLRRVY----EVSQMPEFKGKI--ILIENYDMGSARILVSGVDVW 581
IFG KA P K+ ++ + +++ P + KI + +ENY++ A ++ DV
Sbjct: 579 IFGAKAAPGYHFAKKVIKLITTTAAKIAADPIVREKIRVVFLENYNVSLAEQIIPATDVS 638
Query: 582 LNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
EASGT MK LNG I + DG VE
Sbjct: 639 EQISTASKEASGTGNMKFMLNGAITIGTLDGANVE 673
>sp|P53537|PHSH_VICFA ALPHA-GLUCAN PHOSPHORYLASE, H ISOZYME (STARCH PHOSPHORYLASE H)
>gi|7433824|pir||T12091 starch phosphorylase (EC
2.4.1.1) H, cytosolic isoform - fava bean
>gi|510932|emb|CAA84494.1| (Z35117) alpha 1,4-glucan
phosphorylase type H [Vicia faba]
Length = 842
Score = 98.3 bits (241), Expect = 3e-19
Identities = 142/590 (24%), Positives = 253/590 (42%), Gaps = 109/590 (18%)
Query: 120 KSLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQ------IEKF 173
K + +GGLG LA L + + L LP GL Y++G FKQ I ++G++ +EKF
Sbjct: 133 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRYGLFKQIITKEGQEEVAEDWLEKF 192
Query: 174 PEYNIRE----MPIR---QV-LNNDGT----------PLLIDVPIEDRIVKARVFLVEVG 215
+ I PIR QV +N DG+ L DVPI K + L +
Sbjct: 193 SPWEIVRHDVLYPIRFFGQVEVNPDGSRQWIGGEVIQALAYDVPIPGYQTKNTISL-RLW 251
Query: 216 RVK-------LYLLDTDVPEN----REDDRRICDYLYNAEPDK-----RIKQEILIGIGG 259
K L+L + E+ ++IC LY + + R+KQ+ +
Sbjct: 252 EAKACADDFDLFLFNDGQLESASVLHSRAQQICSVLYPGDATEGGKLLRLKQQYFLCSAS 311
Query: 260 MR--LLKALEIEPG-----------VIHLNEGHPSFANFERIRWFME-KGLTFEEALELV 305
++ + + E G + LN+ HP+ + E +R M+ +GL ++EA +
Sbjct: 312 LQDIISRFKERRQGPWNWSEFPTKVAVQLNDTHPTLSIPELMRLLMDDEGLGWDEAWAVT 371
Query: 306 RATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQ--DKFLGLGKVTP---EDTNFNM 360
T +T HT +P + + + + L + + + +F+ L T ED NM
Sbjct: 372 SKTVAYTNHTVLPEALEKWSQPVMWKLLPRHMEIIEEIDRRFVALISKTRLDLEDEVSNM 431
Query: 361 TVLS--------------IRTSEFVNAVSKLHAKVTRE----MWSNLWPGVPTDEIPIDA 402
+L + +S VN V++LH+ + + + ++WP ++
Sbjct: 432 RILDNNLQKPVVRMANLCVVSSHTVNGVAQLHSDILKSELFASYVSIWPTKFQNK----- 486
Query: 403 ITNGVHTPTWVN---ENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKR 459
TNG+ W+N L+++ ++ K + NL+ + E + +L L AKR
Sbjct: 487 -TNGITPRRWINFCSPELSRIITKWL-KTDKWVTNLDLLTGLREFADNEDLQAEWLSAKR 544
Query: 460 EVIELIRRKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLERLKRIV 518
+ + + +++ +ID ++L +R YKR +L + + R K++
Sbjct: 545 ANKQRLAQYVLQVTGE--------NIDPDSLFDIQVKRIHEYKRQLLNILGVIYRYKKLK 596
Query: 519 N-NPERPVY-----IIFGGKAHPMDEAGKEFLRRVYEVSQM----PEFKG--KIILIENY 566
+PE ++ GGKA K ++ V +V + PE K++ + NY
Sbjct: 597 EMSPEERKSTTARTVMIGGKAFATYTNAKRIVKLVDDVGSVVNSDPEVNSYLKVVFVPNY 656
Query: 567 DMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
++ A +L+ G ++ + +EASGTS MK LN V+ + DG VE
Sbjct: 657 NVSVAEVLIPGSELSQHISTAGMEASGTSNMKFALNRVLIIGTLDGANVE 706
>gb|AAA58226.1| (U18997) alpha-glucan phosphorylase [Escherichia coli]
Length = 815
Score = 93.6 bits (229), Expect = 8e-18
Identities = 98/382 (25%), Positives = 176/382 (45%), Gaps = 56/382 (14%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
IHLN+ HP + E +R + E ++++A E+ +T HT + + +PVD + +
Sbjct: 317 IHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGK 376
Query: 332 KLRLFLRDLPQ--DKFLG-LGKVTPEDTNF---------------NMTVLSIRTSEFVNA 373
L L+ + + D FL L + P DT+ M L++ S VN
Sbjct: 377 ILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNG 436
Query: 374 VSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
VS+LH+ + + ++ ++PG T+ +TNGV W+ N +L+ + D ++G
Sbjct: 437 VSELHSNLMVQSLFADFAKIFPGRFTN------VTNGVTPRRWLAVANPSLSAVLDEHLG 490
Query: 427 KIWREHVNL--EGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPD 484
+ WR ++L E + + + + +A L+ K+ + E I +++
Sbjct: 491 RNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVV------------ 538
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
++ AL +R YKR ++ + + R RI +P+ P IFGGKA
Sbjct: 539 VNPKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMA 598
Query: 541 KEFLRRVYEVSQM----PEF--KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+++ P+ K K++ I NY + A++++ D+ EASGT
Sbjct: 599 KHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGT 658
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
S MK LNG + + DG VE
Sbjct: 659 SNMKFALNGALTIGTLDGANVE 680
>sp|P13031|PHSG_ECOLI GLYCOGEN PHOSPHORYLASE >gi|7427924|pir||PHECGG phosphorylase (EC
2.4.1.1) glgP - Escherichia coli
>gi|2367228|gb|AAC76453.1| (AE000419) glycogen
phosphorylase [Escherichia coli K12]
Length = 815
Score = 93.6 bits (229), Expect = 8e-18
Identities = 98/382 (25%), Positives = 176/382 (45%), Gaps = 56/382 (14%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
IHLN+ HP + E +R + E ++++A E+ +T HT + + +PVD + +
Sbjct: 317 IHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGK 376
Query: 332 KLRLFLRDLPQ--DKFLG-LGKVTPEDTNF---------------NMTVLSIRTSEFVNA 373
L L+ + + D FL L + P DT+ M L++ S VN
Sbjct: 377 ILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNG 436
Query: 374 VSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
VS+LH+ + + ++ ++PG T+ +TNGV W+ N +L+ + D ++G
Sbjct: 437 VSELHSNLMVQSLFADFAKIFPGRFTN------VTNGVTPRRWLAVANPSLSAVLDEHLG 490
Query: 427 KIWREHVNL--EGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPD 484
+ WR ++L E + + + + +A L+ K+ + E I +++
Sbjct: 491 RNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVV------------ 538
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
++ AL +R YKR ++ + + R RI +P+ P IFGGKA
Sbjct: 539 VNPKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMA 598
Query: 541 KEFLRRVYEVSQM----PEF--KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+++ P+ K K++ I NY + A++++ D+ EASGT
Sbjct: 599 KHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGT 658
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
S MK LNG + + DG VE
Sbjct: 659 SNMKFALNGALTIGTLDGANVE 680
>gb|AAA23874.1| (J03966) alpha-glucan phosphorylase (EC 2.4.1.1) [Escherichia coli]
Length = 809
Score = 93.6 bits (229), Expect = 8e-18
Identities = 98/382 (25%), Positives = 176/382 (45%), Gaps = 56/382 (14%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
IHLN+ HP + E +R + E ++++A E+ +T HT + + +PVD + +
Sbjct: 311 IHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGK 370
Query: 332 KLRLFLRDLPQ--DKFLG-LGKVTPEDTNF---------------NMTVLSIRTSEFVNA 373
L L+ + + D FL L + P DT+ M L++ S VN
Sbjct: 371 ILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNG 430
Query: 374 VSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
VS+LH+ + + ++ ++PG T+ +TNGV W+ N +L+ + D ++G
Sbjct: 431 VSELHSNLMVQSLLADFAKIFPGRFTN------VTNGVTPRRWLAVANPSLSAVLDEHLG 484
Query: 427 KIWREHVNL--EGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPD 484
+ WR ++L E + + + + +A L+ K+ + E I +++
Sbjct: 485 RNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVV------------ 532
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
++ AL +R YKR ++ + + R RI +P+ P IFGGKA
Sbjct: 533 VNPKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMA 592
Query: 541 KEFLRRVYEVSQM----PEF--KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+++ P+ K K++ I NY + A++++ D+ EASGT
Sbjct: 593 KHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGT 652
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
S MK LNG + + DG VE
Sbjct: 653 SNMKFALNGALTIGTLDGANVE 674
>emb|CAA34807.1| (X16931) glycogen phosphorylase (AA 1 - 790) [Escherichia coli]
Length = 790
Score = 91.3 bits (223), Expect = 4e-17
Identities = 97/382 (25%), Positives = 176/382 (45%), Gaps = 56/382 (14%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
IHLN+ HP + E +R + E ++++A E+ +T HT + + +PVD + +
Sbjct: 292 IHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGK 351
Query: 332 KLRLFLRDLPQ--DKFLG-LGKVTPEDTNF---------------NMTVLSIRTSEFVNA 373
L L+ + + D FL L + P DT+ M L++ S VN
Sbjct: 352 ILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNG 411
Query: 374 VSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
VS+LH+ + + ++ ++PG T+ +TNGV W+ N +L+ + D +G
Sbjct: 412 VSELHSNLMVQSLFADFAKIFPGRFTN------VTNGVTPRRWLAVANPSLSAVLDGTLG 465
Query: 427 KIWREHVNL--EGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPD 484
+ WR ++L E + + + + +A+++ K+ + E I +++
Sbjct: 466 RNWRTDLSLLNELQQHCDFPMVNHAVHQANVENKKRLAEYIAQQLNVV------------ 513
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
++ AL +R YKR ++ + + R RI +P+ P IFGGKA
Sbjct: 514 VNPKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMA 573
Query: 541 KEFLRRVYEVSQM----PEF--KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+++ P+ K K++ I NY + A++++ D+ EASGT
Sbjct: 574 KHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGT 633
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
S MK LNG + + DG VE
Sbjct: 634 SNMKFALNGALTIGTLDGANVE 655
>sp|P39123|PHSG_BACSU GLYCOGEN PHOSPHORYLASE >gi|480288|pir||S36628 glycogen
phosphorylase (EC 2.4.1.1) - Bacillus subtilis
>gi|2145607|pir||S40052 glycogen phosphorylase (EC
2.4.1.1) glgP - Bacillus subtilis
>gi|397492|emb|CAA81044.1| (Z25795) Glycogen
Phosphorylase [Bacillus subtilis]
>gi|2293140|gb|AAC00218.1| (AF008220) glycogen
phosphorylase [Bacillus subtilis]
>gi|2635578|emb|CAB15072.1| (Z99119) glycogen
phosphorylase [Bacillus subtilis]
Length = 798
Score = 90.9 bits (222), Expect = 5e-17
Identities = 134/576 (23%), Positives = 229/576 (39%), Gaps = 110/576 (19%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPEYNIREMPIRQ 185
+GGLG LA L + + L LP +G+ YKHG F+Q+I DG Q+E PE ++ + +
Sbjct: 114 NGGLGRLAACFLDSLASLNLPGHGMGIRYKHGLFEQKIV-DGHQVE-LPEQWLKNGNVWE 171
Query: 186 VLNNDGTPLLIDVPI------------------EDRIVKARVFLV-----EVGRVKLYLL 222
V N D +DVP + IV A + + E G V L
Sbjct: 172 VRNADQA---VDVPFWGEVHMTEKSGRLHFRHEQATIVTAVPYDIPIIGYETGTVNTLRL 228
Query: 223 DTDVPENREDDRRICDYLYNAE-------PDK--------RIKQEILIGIGGMRLL---- 263
P I Y E PD R+KQ+ + ++ +
Sbjct: 229 WNAEPYAHYHGGNILSYKRETEAVSEFLYPDDTHDEGKILRLKQQYFLVCASLKSIVNNY 288
Query: 264 -KALEIEPGV-----IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTP 316
K + G+ IH+N+ HP+ A E +R + E+ +++EEA + T +T HT
Sbjct: 289 RKTHKSLSGLHKKVSIHINDTHPALAVPELMRILLDEENMSWEEAWHITVHTISYTNHTT 348
Query: 317 VPAGHDVFPVDFVRE---KLRLFLRDLPQDKFLGLGKVTPEDTN------------FNMT 361
+ + +P+ + ++ + + ++ + + + P D M
Sbjct: 349 LSEALEKWPIHLFKPLLPRMYMIIEEINERFCRAVWEKYPGDWKRIENMAITAHGVVKMA 408
Query: 362 VLSIRTSEFVNAVSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---N 414
L+I S VN V+K+H+ + +E + L+P ++ TNG+ W+ N
Sbjct: 409 HLAIVGSYSVNGVAKIHSDILKEREMRDFHLLFPNRFNNK------TNGIAHRRWLLKAN 462
Query: 415 ENLAKLYDIYIGKIWREH----VNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIM 470
L+ + IG W + + LE YA + + K K+E+ +LI
Sbjct: 463 PGLSAIITEAIGDEWVKQPESLIRLEP--YATDPAFIEQFQNNKSKKKQELADLIFCTA- 519
Query: 471 KRNERLGIDEPLPDIDENALIIGFARRFATYKRAILLFTDL----ERLKRIVNNPERPVY 526
G+ ++ ++ +R YKR +L + RLK P
Sbjct: 520 ------GVV-----VNPESIFDVQVKRLHAYKRQLLNVLHIMYLYNRLKEDSGFSIYPQT 568
Query: 527 IIFGGKAHPMDEAGKEFLRRVYEVSQMPEFKG------KIILIENYDMGSARILVSGVDV 580
IFG KA P K+ ++ ++ V++ + K++ +ENY + A + DV
Sbjct: 569 FIFGAKASPSYYYAKKIIKLIHSVAEKVNYDPAVKQLIKVVFLENYRVSMAERIFPASDV 628
Query: 581 WLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
EASGT MK +NG + + DG +E
Sbjct: 629 SEQISTASKEASGTGNMKFMMNGALTIGTHDGANIE 664
>sp|P32811|PHSH_SOLTU ALPHA-GLUCAN PHOSPHORYLASE, H ISOZYME (STARCH PHOSPHORYLASE H)
>gi|100452|pir||A40995 starch phosphorylase (EC 2.4.1.1)
H [similarity] - potato >gi|169473|gb|AAA33809.1|
(M69038) alpha-glucan phosphorylase type H isozyme
[Solanum tuberosum]
Length = 838
Score = 90.9 bits (222), Expect = 5e-17
Identities = 140/596 (23%), Positives = 242/596 (40%), Gaps = 119/596 (19%)
Query: 120 KSLPIYSGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQ------IEKF 173
K + +GGLG LA L + + L LP GL Y++G FKQ I + G++ +EKF
Sbjct: 127 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRYGLFKQLITKAGQEEVPEDWLEKF 186
Query: 174 PEYNIRE----MPIRQVLNNDGTP--------------LLIDVPIEDRIVK----ARVFL 211
+ I PIR + + P L DVPI K R++
Sbjct: 187 SPWEIVRHDVVFPIRFFGHVEVLPSGSRKWVGGEVLQALAYDVPIPGYRTKNTNSLRLWE 246
Query: 212 VEVGR--VKLYLLDTD----VPENREDDRRICDYLYNAEPDK-----RIKQEILIGIGGM 260
+ L+L + + ++IC LY + + R+KQ+ + +
Sbjct: 247 AKASSEDFNLFLFNDGQYDAAAQLHSRAQQICAVLYPGDATENGKLLRLKQQFFLCSASL 306
Query: 261 R--LLKALEIEPG-------------VIHLNEGHPSFANFERIRWFME-KGLTFEEALEL 304
+ + + E E G I LN+ HP+ E +R M+ +GL ++E+ +
Sbjct: 307 QDIIARFKEREDGKGSHQWSEFPKKVAIQLNDTHPTLTIPELMRLLMDDEGLGWDESWNI 366
Query: 305 VRATSVFTTHTPVPAGHDVFP-----------VDFVREKLRLFL-----------RDLPQ 342
T +T HT +P + + ++ + E + F+ +P
Sbjct: 367 TTRTIAYTNHTVLPEALEKWSQAVMWKLLPRHMEIIEEIDKRFVATIMSERPDLENKMPS 426
Query: 343 DKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVSKLHAKVTR-EMWS---NLWPGVPTDEI 398
+ L P N+ V+S T VN V++LH+ + + E+++ ++WP
Sbjct: 427 MRILDHNATKPVVHMANLCVVSSHT---VNGVAQLHSDILKAELFADYVSVWP------T 477
Query: 399 PIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH--VNLEGIWYAIERIPDSEL---WEA 453
TNG+ W+ +L I + + NLE + E +SEL WE+
Sbjct: 478 KFQNKTNGITPRRWIRFCSPELSHIITKWLKTDQWVTNLELLANLREFADNSELHAEWES 537
Query: 454 HLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLE 512
A ++ R + + ID N+L +R YKR +L + +
Sbjct: 538 AKMANKQ-----------RLAQYILHVTGVSIDPNSLFDIQVKRIHEYKRQLLNILGVIY 586
Query: 513 RLKRIVN-NPER-----PVYIIFGGKAHPMDEAGKEFLRRVYEVSQM----PEFKG--KI 560
R K++ +PE P ++ GGKA K ++ V +V + P+ K+
Sbjct: 587 RYKKLKGMSPEERKNTTPRTVMIGGKAFATYTNAKRIVKLVTDVGDVVNSDPDVNDYLKV 646
Query: 561 ILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
+ + NY++ A +L+ G ++ + +EASGTS MK LNG + + DG VE
Sbjct: 647 VFVPNYNVSVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVE 702
>gi|11560087 liver glycogen phosphorylase [Rattus norvegicus]
>gi|585688|sp|P09811|PHS1_RAT GLYCOGEN PHOSPHORYLASE,
LIVER FORM >gi|111725|pir||S22338 glycogen phosphorylase
(EC 2.4.1.1), hepatic - rat >gi|56314|emb|CAA45083.1|
(X63515) glycogen phosphorylase liver type [Rattus
norvegicus]
Length = 850
Score = 90.1 bits (220), Expect = 9e-17
Identities = 136/576 (23%), Positives = 236/576 (40%), Gaps = 95/576 (16%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEID------------RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y++G F Q+I R G EK
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKA 193
Query: 174 -PEYNIREMPIRQVLNNDG------TPLLIDVPIED-------------RIVKARV---F 210
PE+ + +V + T +++ +P + R+ AR F
Sbjct: 194 RPEFMLPVHFYGRVEHTQAGTKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDF 253
Query: 211 LVEVGRVKLYL---LDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM----RLL 263
++ V Y+ LD ++ EN D + + + R+KQE + + R
Sbjct: 254 NLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDVIRRF 312
Query: 264 KALEI--EPGV------------IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRAT 308
KA + + GV I LN+ HP+ A E +R F++ + L + +A E+ + T
Sbjct: 313 KASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKT 372
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PVD V + L L+ + + L ++ P+D +
Sbjct: 373 FAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLI 432
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTP 410
NM L I VN V+K+H+ + + + + D+ TNG+
Sbjct: 433 EEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNK--TNGITPR 490
Query: 411 TWVNENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIM 470
W+ L D+ KI ++V + +++ RE+ ++ + +
Sbjct: 491 RWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVGDDIF------LREIAKVKQENKL 544
Query: 471 KRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVY 526
K ++ L + + I+ +++ +R YKR +L + T R+K+ P
Sbjct: 545 KFSQFLEKEYKVK-INPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFVPRT 603
Query: 527 IIFGGKAHPMDEAGKEFLRRVYEVSQ------MPEFKGKIILIENYDMGSARILVSGVDV 580
+I GGKA P K ++ V V++ M K K+I +ENY + A ++ D+
Sbjct: 604 VIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDL 663
Query: 581 WLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
EASGT MK LNG + + DG VE
Sbjct: 664 SEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVE 699
>pir||A82511 maltodextrin phosphorylase VCA0013 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9657392|gb|AAF95927.1|
(AE004345) maltodextrin phosphorylase [Vibrio cholerae]
Length = 817
Score = 89.3 bits (218), Expect = 2e-16
Identities = 136/587 (23%), Positives = 231/587 (39%), Gaps = 120/587 (20%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQ---------IEKFPEY 176
+GGLG LA + + + P + GL Y++G FKQ + +GRQ +E +P +
Sbjct: 120 NGGLGRLAACFMDSCAAQEYPTVGYGLHYEYGLFKQSFE-EGRQKEAPDAWCGVEGYP-W 177
Query: 177 NIREMPIRQ---------VLNNDGTP-------LLI-----DVPI----EDRIVKARVF- 210
+ ++Q V+N +G +L+ D+PI D + R++
Sbjct: 178 EVARPELKQEIGFYGHVEVVNENGKERRRWVPGMLVQAMPWDLPIVGYQSDTVYPLRLWE 237
Query: 211 -----------------------LVEVGRVKLYLLDTDVPENREDDRRICDYLYNAEPDK 247
L++ G + L D E + R + Y ++A +
Sbjct: 238 CRAIAPFSLESFNNGNYFEAQHALIDAGNITKVLYPNDNHEKGKTLRLMQQYFHSAASVR 297
Query: 248 RIKQEILIGIGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVR 306
I + + L E I LN+ HP+ A E +R + EK +++E A +
Sbjct: 298 DILRRHEAAGHALADLPKYE----TIQLNDTHPTIAIPELMRILIDEKLMSWEAAWAICS 353
Query: 307 ATSVFTTHTPVPAGHDVFPVDFVREKLRLFL--------RDLPQDKFLGLGKVTPE---- 354
T +T HT +P + + ++ L + R L Q + G V +
Sbjct: 354 HTFAYTNHTLLPEALETWSESLIQRLLPRHMEIIYEINHRFLQQVRAKWPGDVAKQQKLS 413
Query: 355 --DTNFNMTV----LSIRTSEFVNAVSKLHAK-VTREMWSN---LWPGVPTDEIPIDAIT 404
+ F+ V L + S VN V+ LH++ V R+++ L+PG I +T
Sbjct: 414 IIEEGFHRMVRMANLCVVGSYAVNGVAALHSELVKRDLFPEFVELYPG------KIQNVT 467
Query: 405 NGVHTPTWV---NENLAKLYDIYIGKIWREHVN--LEGIWYAIERIPDSELWEAHLKAKR 459
NG+ W+ N L+ L IG W ++ + YA + E K
Sbjct: 468 NGITPRRWLKFCNPGLSALISEKIGHEWPAKLDQLTKVAQYAEDAAFQKRFMEVKKANKA 527
Query: 460 EVIELIRRKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLERLKRIV 518
+ + ++ + +GI+ +D NA+ +R YKR L + L R++
Sbjct: 528 RLADWVK-------DHMGIE-----LDTNAIFDVQIKRLHEYKRQHLNMLHILSLYHRLI 575
Query: 519 NNPE---RPVYIIFGGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMG 569
N+P P + F KA P KE + + ++Q K K++ I +Y +
Sbjct: 576 NDPSFDMHPRVVFFAAKAAPGYHLAKEIIYAINMIAQKVNNDPRVGNKLKVVFIPDYRVS 635
Query: 570 SARILVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
A I++ DV EASGT MK LNG + + DG VE
Sbjct: 636 MAEIIIPAADVSEQISTAGKEASGTGNMKMALNGALTIGTMDGANVE 682
>emb|CAA44069.1| (X62142) glycogen phosphorylase 1 [Dictyostelium discoideum]
Length = 846
Score = 88.9 bits (217), Expect = 2e-16
Identities = 97/383 (25%), Positives = 165/383 (42%), Gaps = 54/383 (14%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ E R + E+GL +EEA ++V T +T HT +P +++PV + +
Sbjct: 341 IQLNDTHPTIGVVELFRKLIDEEGLQWEEAWDIVTKTFAYTNHTILPEALEMWPVSLIED 400
Query: 332 KL-----------RLFLRDLPQD------KFLGLGKVTP-EDTNFNMTVLSIRTSEFVNA 373
L FL + Q K GL + E+ M L+I S VN
Sbjct: 401 LLPRHMQLIYGINHRFLIQVTQKWPGDIGKMRGLSIIQEGEEKRVRMAHLAIVGSHCVNG 460
Query: 374 VSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
V+ +H+++ + + LWP ++ TNGV W+ N L+ ++ ++G
Sbjct: 461 VAAMHSELVKHKVFPDFFCLWPEKFQNK------TNGVTPRRWIEQANPGLSAIFTKWLG 514
Query: 427 KIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDID 486
+ NLE + E + + EL K+ + + I+K GI ++
Sbjct: 515 TD-KWTTNLELVKGIKEHMDNPELIAEWKYVKQGNKQRLAEFILKH---CGIH-----VN 565
Query: 487 ENALIIGFARRFATYKRAIL-------LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEA 539
NAL +R YKR +L + ++++ P +IF GKA P
Sbjct: 566 PNALFDVHIKRIHEYKRQLLNILSVIYRYLSIKKMSPKDRAQVVPRVVIFAGKAAPGYVM 625
Query: 540 GKEFLRRVYEVSQMPEFKG------KIILIENYDMGSARILVSGVDVWLNTPRRPLEASG 593
K ++ + V+++ K++ I NY++ A+++V D+ EASG
Sbjct: 626 AKRHIKLINSVAEVINRDKEVDQYLKVVFIANYNVSIAQVIVPASDINQQISTAGTEASG 685
Query: 594 TSGMKAGLNGVINLSVFDGWWVE 616
TS MK +NG + + DG VE
Sbjct: 686 TSNMKFTMNGSLIIGTLDGANVE 708
>sp|Q00766|PHS1_DICDI GLYCOGEN PHOSPHORYLASE 1 (GP1) >gi|478597|pir||S20595 glycogen
phosphorylase (EC 2.4.1.1) 1 - slime mold
(Dictyostelium discoideum)
Length = 853
Score = 88.9 bits (217), Expect = 2e-16
Identities = 97/383 (25%), Positives = 165/383 (42%), Gaps = 54/383 (14%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ E R + E+GL +EEA ++V T +T HT +P +++PV + +
Sbjct: 348 IQLNDTHPTIGVVELFRKLIDEEGLQWEEAWDIVTKTFAYTNHTILPEALEMWPVSLIED 407
Query: 332 KL-----------RLFLRDLPQD------KFLGLGKVTP-EDTNFNMTVLSIRTSEFVNA 373
L FL + Q K GL + E+ M L+I S VN
Sbjct: 408 LLPRHMQLIYGINHRFLIQVTQKWPGDIGKMRGLSIIQEGEEKRVRMAHLAIVGSHCVNG 467
Query: 374 VSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
V+ +H+++ + + LWP ++ TNGV W+ N L+ ++ ++G
Sbjct: 468 VAAMHSELVKHKVFPDFFCLWPEKFQNK------TNGVTPRRWIEQANPGLSAIFTKWLG 521
Query: 427 KIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDID 486
+ NLE + E + + EL K+ + + I+K GI ++
Sbjct: 522 TD-KWTTNLELVKGIKEHMDNPELIAEWKYVKQGNKQRLAEFILKH---CGIH-----VN 572
Query: 487 ENALIIGFARRFATYKRAIL-------LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEA 539
NAL +R YKR +L + ++++ P +IF GKA P
Sbjct: 573 PNALFDVHIKRIHEYKRQLLNILSVIYRYLSIKKMSPKDRAQVVPRVVIFAGKAAPGYVM 632
Query: 540 GKEFLRRVYEVSQMPEFKG------KIILIENYDMGSARILVSGVDVWLNTPRRPLEASG 593
K ++ + V+++ K++ I NY++ A+++V D+ EASG
Sbjct: 633 AKRHIKLINSVAEVINRDKEVDQYLKVVFIANYNVSIAQVIVPASDINQQISTAGTEASG 692
Query: 594 TSGMKAGLNGVINLSVFDGWWVE 616
TS MK +NG + + DG VE
Sbjct: 693 TSNMKFTMNGSLIIGTLDGANVE 715
>gb|AAD46887.1|AF160947_1 (AF160947) BcDNA.LD24485 [Drosophila melanogaster]
>gi|7296006|gb|AAF51303.1| (AE003584) GlyP gene product
[Drosophila melanogaster]
Length = 844
Score = 88.5 bits (216), Expect = 3e-16
Identities = 95/377 (25%), Positives = 161/377 (42%), Gaps = 46/377 (12%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R + E+ LT+E+A ++ + +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPVSLLES 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + FL + V P+D + NM LSI S VN
Sbjct: 396 ILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKRINMAHLSIVGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIW 429
V+ +H+++ ++ ++ + + P TNG+ W+ N L+ L IG W
Sbjct: 456 VAAIHSQILKDSLFHDFYEMEPQK---FQNKTNGITPRRWLLLCNPGLSDLIAEKIGDEW 512
Query: 430 REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENA 489
H ++++ + W +R V + + +K L D + I+ ++
Sbjct: 513 PVH---------LDQLVALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYGVK-INPSS 562
Query: 490 LIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
+ +R YKR +L + T R+K+ P I+ GGKA P K+ ++
Sbjct: 563 MFDIQVKRIHEYKRQLLNCLHIITLYNRIKKDPTANFTPRTIMIGGKAAPGYYVAKQIIK 622
Query: 546 RVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKA 599
+ V + K K+I +ENY + A ++ D+ EASGT MK
Sbjct: 623 LICAVGNVVNNDPIVGDKLKVIFLENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKF 682
Query: 600 GLNGVINLSVFDGWWVE 616
LNG + + DG VE
Sbjct: 683 QLNGALTIGTLDGANVE 699
>gi|4506353 phosphorylase, glycogen; liver (Hers disease, glycogen storage
disease type VI); Phosphorylase, glycogen, liver [Homo
sapiens] >gi|11433353|ref|XP_007225.1| phosphorylase,
glycogen; liver (Hers disease, glycogen storage disease
type VI) [Homo sapiens] >gi|6648082|sp|P06737|PHS1_HUMAN
GLYCOGEN PHOSPHORYLASE, LIVER FORM
>gi|11514105|pdb|1EM6|A Chain A, Human Liver Glycogen
Phosphorylase A Complexed With Glcnac And Cp-526,423
>gi|11514106|pdb|1EM6|B Chain B, Human Liver Glycogen
Phosphorylase A Complexed With Glcnac And Cp-526,423
>gi|11514121|pdb|1EXV|A Chain A, Human Liver Glycogen
Phosphorylase A Complexed With Glcnac And Cp-403,700
>gi|11514122|pdb|1EXV|B Chain B, Human Liver Glycogen
Phosphorylase A Complexed With Glcnac And Cp-403,700
>gi|3157406|emb|CAA75517.1| (Y15233) liver glycogen
phosphorylase [Homo sapiens]
Length = 847
Score = 87.8 bits (214), Expect = 5e-16
Identities = 167/712 (23%), Positives = 278/712 (38%), Gaps = 160/712 (22%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQ---------EID---RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y++G F Q E D R G EK
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKS 193
Query: 174 -PEYNIREMPIRQVLN-NDGTP---------LLIDVPIED---------RIVKARV---F 210
PE+ + +V + N GT L D P+ R+ AR F
Sbjct: 194 RPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDF 253
Query: 211 LVEVGRVKLYL---LDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM----RLL 263
+ V Y+ LD ++ EN D + + + R+KQE + + R
Sbjct: 254 NLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIIRRF 312
Query: 264 KALEI--------------EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRAT 308
KA + + I LN+ HP+ A E +R F++ + L + +A EL + T
Sbjct: 313 KASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKT 372
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PVD V + L L + + L ++ P+D +
Sbjct: 373 FAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLI 432
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTP 410
NM L I S VN V+K+H+ + + + + D+ TNG+
Sbjct: 433 EEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNK--TNGITPR 490
Query: 411 TWV---NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRR 467
W+ N LA+L IG+ + + + S+L + H +V
Sbjct: 491 RWLLLCNPGLAELIAEKIGEDYVKDL--------------SQLTKLHSFLGDDVFLRELA 536
Query: 468 KIMKRNE----RLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVN 519
K+ + N+ + E I+ +++ +R YKR +L + T R+K+
Sbjct: 537 KVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPK 596
Query: 520 NPERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQ------MPEFKGKIILIENYDMGSARI 573
P +I GGKA P K ++ + V+ M K K+I +ENY + A
Sbjct: 597 KLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEK 656
Query: 574 LVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWV---EGYNGRNGWVIG--- 627
++ D+ EASGT MK LNG + + DG V E N ++ G
Sbjct: 657 VIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRI 716
Query: 628 --DATLEPE-TEADDYLDAM-----------------SLYDLLENVVVPLYYENR----- 662
A L+ + EA +Y +A+ DL ++++ L+Y +R
Sbjct: 717 DDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFA 776
Query: 663 -------------------SAWIRMMKESIMSIAPRFSTYRMVKEYISKFYS 695
AW M+ ++I + + +FS+ R +KEY ++
Sbjct: 777 DYEAYVKCQDKVSQLYMNPKAWNTMVLKNI-AASGKFSSDRTIKEYAQNIWN 827
>pdb|1FA9|A Chain A, Human Liver Glycogen Phosphorylase A Complexed With Amp
Length = 846
Score = 87.8 bits (214), Expect = 5e-16
Identities = 167/712 (23%), Positives = 278/712 (38%), Gaps = 160/712 (22%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQ---------EID---RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y++G F Q E D R G EK
Sbjct: 133 NGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKS 192
Query: 174 -PEYNIREMPIRQVLN-NDGTP---------LLIDVPIED---------RIVKARV---F 210
PE+ + +V + N GT L D P+ R+ AR F
Sbjct: 193 RPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDF 252
Query: 211 LVEVGRVKLYL---LDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM----RLL 263
+ V Y+ LD ++ EN D + + + R+KQE + + R
Sbjct: 253 NLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIIRRF 311
Query: 264 KALEI--------------EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRAT 308
KA + + I LN+ HP+ A E +R F++ + L + +A EL + T
Sbjct: 312 KASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKT 371
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PVD V + L L + + L ++ P+D +
Sbjct: 372 FAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLI 431
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTP 410
NM L I S VN V+K+H+ + + + + D+ TNG+
Sbjct: 432 EEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNK--TNGITPR 489
Query: 411 TWV---NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRR 467
W+ N LA+L IG+ + + + S+L + H +V
Sbjct: 490 RWLLLCNPGLAELIAEKIGEDYVKDL--------------SQLTKLHSFLGDDVFLRELA 535
Query: 468 KIMKRNE----RLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVN 519
K+ + N+ + E I+ +++ +R YKR +L + T R+K+
Sbjct: 536 KVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPK 595
Query: 520 NPERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQ------MPEFKGKIILIENYDMGSARI 573
P +I GGKA P K ++ + V+ M K K+I +ENY + A
Sbjct: 596 KLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEK 655
Query: 574 LVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWV---EGYNGRNGWVIG--- 627
++ D+ EASGT MK LNG + + DG V E N ++ G
Sbjct: 656 VIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRI 715
Query: 628 --DATLEPE-TEADDYLDAM-----------------SLYDLLENVVVPLYYENR----- 662
A L+ + EA +Y +A+ DL ++++ L+Y +R
Sbjct: 716 DDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFA 775
Query: 663 -------------------SAWIRMMKESIMSIAPRFSTYRMVKEYISKFYS 695
AW M+ ++I + + +FS+ R +KEY ++
Sbjct: 776 DYEAYVKCQDKVSQLYMNPKAWNTMVLKNI-AASGKFSSDRTIKEYAQNIWN 826
>pdb|1FC0|A Chain A, Human Liver Glycogen Phosphorylase Complexed With
N-Acetyl- Beta-D-Glucopyranosylamine
>gi|10120743|pdb|1FC0|B Chain B, Human Liver Glycogen
Phosphorylase Complexed With N-Acetyl-
Beta-D-Glucopyranosylamine
Length = 846
Score = 87.8 bits (214), Expect = 5e-16
Identities = 167/712 (23%), Positives = 278/712 (38%), Gaps = 160/712 (22%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQ---------EID---RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y++G F Q E D R G EK
Sbjct: 133 NGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKS 192
Query: 174 -PEYNIREMPIRQVLN-NDGTP---------LLIDVPIED---------RIVKARV---F 210
PE+ + +V + N GT L D P+ R+ AR F
Sbjct: 193 RPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDF 252
Query: 211 LVEVGRVKLYL---LDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM----RLL 263
+ V Y+ LD ++ EN D + + + R+KQE + + R
Sbjct: 253 NLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIIRRF 311
Query: 264 KALEI--------------EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRAT 308
KA + + I LN+ HP+ A E +R F++ + L + +A EL + T
Sbjct: 312 KASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKT 371
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PVD V + L L + + L ++ P+D +
Sbjct: 372 FAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLI 431
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTP 410
NM L I S VN V+K+H+ + + + + D+ TNG+
Sbjct: 432 EEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNK--TNGITPR 489
Query: 411 TWV---NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRR 467
W+ N LA+L IG+ + + + S+L + H +V
Sbjct: 490 RWLLLCNPGLAELIAEKIGEDYVKDL--------------SQLTKLHSFLGDDVFLRELA 535
Query: 468 KIMKRNE----RLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVN 519
K+ + N+ + E I+ +++ +R YKR +L + T R+K+
Sbjct: 536 KVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPK 595
Query: 520 NPERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQ------MPEFKGKIILIENYDMGSARI 573
P +I GGKA P K ++ + V+ M K K+I +ENY + A
Sbjct: 596 KLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEK 655
Query: 574 LVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWV---EGYNGRNGWVIG--- 627
++ D+ EASGT MK LNG + + DG V E N ++ G
Sbjct: 656 VIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRI 715
Query: 628 --DATLEPE-TEADDYLDAM-----------------SLYDLLENVVVPLYYENR----- 662
A L+ + EA +Y +A+ DL ++++ L+Y +R
Sbjct: 716 DDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFA 775
Query: 663 -------------------SAWIRMMKESIMSIAPRFSTYRMVKEYISKFYS 695
AW M+ ++I + + +FS+ R +KEY ++
Sbjct: 776 DYEAYVKCQDKVSQLYMNPKAWNTMVLKNI-AASGKFSSDRTIKEYAQNIWN 826
>gb|AAD27759.1|AF073178_1 (AF073178) glycogen phosphorylase [Drosophila melanogaster]
>gi|4689102|gb|AAD27760.1|AF073179_1 (AF073179) glycogen
phosphorylase [Drosophila melanogaster]
>gi|5305433|gb|AAD41649.1|AF073177_1 (AF073177) glycogen
phosphorylase [Drosophila melanogaster]
Length = 844
Score = 86.6 bits (211), Expect = 1e-15
Identities = 94/377 (24%), Positives = 160/377 (41%), Gaps = 46/377 (12%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R + E+ LT+E+A ++ + +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPVSLLES 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + FL + V P+D + NM LSI S VN
Sbjct: 396 ILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKRINMAHLSIVGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIW 429
V+ +H+++ ++ ++ + + P TNG+ W+ N L+ L IG W
Sbjct: 456 VAAIHSQILKDSLFHDFYEMEPQK---FQNKTNGITPRRWLLLCNPGLSDLIAEKIGDEW 512
Query: 430 REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENA 489
H ++++ + W +R V + + +K L D + I+ ++
Sbjct: 513 PVH---------LDQLVALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYGVK-INPSS 562
Query: 490 LIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
+ +R YKR +L + T R+K+ P I+ GGKA P K+ ++
Sbjct: 563 MFDIQVKRIHEYKRQLLNCLHIITLYNRIKKDPTANFTPRTIMIGGKAAPGYYVAKQIIK 622
Query: 546 RVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKA 599
+ V + K +I +ENY + A ++ D+ EASGT MK
Sbjct: 623 LICAVGNVVNNDPIVGDKLNVIFLENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKF 682
Query: 600 GLNGVINLSVFDGWWVE 616
LNG + + DG VE
Sbjct: 683 QLNGALTIGTLDGANVE 699
>gb|AAG00588.1|AF288783_1 (AF288783) glycogen phosphorylase [Mus musculus]
Length = 850
Score = 85.4 bits (208), Expect = 2e-15
Identities = 159/708 (22%), Positives = 279/708 (38%), Gaps = 152/708 (21%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFK---------QEID---RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y++G F +E D R G EK
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKA 193
Query: 174 -PEYNIREMPI----RQVLNNDGTP---------LLIDVPIED---------RIVKARV- 209
PE+ +P+ R GT L D P+ R+ AR
Sbjct: 194 RPEF---VLPVHFYGRVEHTQTGTKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAP 250
Query: 210 --FLVEVGRVKLYL---LDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM---- 260
F ++ V Y+ LD ++ EN D + + + R+KQE + +
Sbjct: 251 NDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDVI 309
Query: 261 RLLKALEI--------------EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELV 305
R KA + + I LN+ HP+ A E +R F++ + L + +A E+
Sbjct: 310 RRFKASKFGSKDGMGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWAKAWEIT 369
Query: 306 RATSVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN----- 357
+ T +T HT +P + +PV+ V + L L + + L ++ P+D +
Sbjct: 370 KKTFAYTNHTVLPEALERWPVELVEKLLPRHLEIIYEINQKHLDRIVALFPKDISRMRRM 429
Query: 358 ----------FNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGV 407
NM L I VN V+K+H+ + + + + D+ TNG+
Sbjct: 430 SLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNK--TNGI 487
Query: 408 HTPTWVNENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRR 467
W+ L D+ KI ++V + +++ RE+ ++ +
Sbjct: 488 TPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVSDDIF------LREIAKVKQE 541
Query: 468 KIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPER 523
+K ++ L + + I+ +++ +R YKR +L + T R+K+
Sbjct: 542 NKLKFSQFLEKEYKVK-INPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFV 600
Query: 524 PVYIIFGGKAHPMDEAGKEFLRRVYEVSQ------MPEFKGKIILIENYDMGSARILVSG 577
P +I GGKA P K ++ + V++ M K K+I +ENY + A ++
Sbjct: 601 PRTVIIGGKAAPGYHMAKMIIKLITSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPA 660
Query: 578 VDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWV---EGYNGRNGWVIG-----DA 629
D+ EASGT MK LNG + + DG V E N ++ G A
Sbjct: 661 TDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVA 720
Query: 630 TLEPE-TEADDYLDAM-----------------SLYDLLENVVVPLYYE----------- 660
L+ + EA +Y +A+ + DL ++++ L+Y
Sbjct: 721 ALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEA 780
Query: 661 -------------NRSAWIRMMKESIMSIAPRFSTYRMVKEYISKFYS 695
N+ AW M+ ++I + + +FS+ R +KEY ++
Sbjct: 781 YVKCQEKVSQLYMNQKAWNTMVLKNI-AASGKFSSDRTIKEYAKDIWN 827
>gb|AAC17450.1| (AF066858) liver glycogen phosphorylase [Homo sapiens]
Length = 847
Score = 85.4 bits (208), Expect = 2e-15
Identities = 166/712 (23%), Positives = 277/712 (38%), Gaps = 160/712 (22%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQ---------EID---RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y++G F Q E D R G EK
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKS 193
Query: 174 -PEYNIREMPIRQVLN-NDGTP---------LLIDVPIED---------RIVKARV---F 210
PE+ + +V + N GT L D P+ R+ AR F
Sbjct: 194 RPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDF 253
Query: 211 LVEVGRVKLYL---LDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM----RLL 263
+ V Y+ LD ++ EN D + + + R+KQE + + R
Sbjct: 254 NLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIIRRF 312
Query: 264 KALEI--------------EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRAT 308
KA + + I LN+ HP+ A E +R F++ + L + +A EL + T
Sbjct: 313 KASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKT 372
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PVD V + L L + + L ++ P+D +
Sbjct: 373 FAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLI 432
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTP 410
NM L I S VN V+K+H+ + + + + D+ TNG+
Sbjct: 433 EEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNK--TNGITPR 490
Query: 411 TWV---NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRR 467
W+ N LA+L IG+ + + + S+L + H +V
Sbjct: 491 RWLLLCNPGLAELIAEKIGEDYVKDL--------------SQLTKLHSFLGDDVFLRELA 536
Query: 468 KIMKRNE----RLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVN 519
K+ + N+ + E I+ +++ + YKR +L + T R+K+
Sbjct: 537 KVKQENKLKFSQFLETEYKVKINPSSMFDVQVKSIHEYKRQLLNCLHVITMYNRIKKDPK 596
Query: 520 NPERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQ------MPEFKGKIILIENYDMGSARI 573
P +I GGKA P K ++ + V+ M K K+I +ENY + A
Sbjct: 597 KLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEK 656
Query: 574 LVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWV---EGYNGRNGWVIG--- 627
++ D+ EASGT MK LNG + + DG V E N ++ G
Sbjct: 657 VIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRI 716
Query: 628 --DATLEPE-TEADDYLDAM-----------------SLYDLLENVVVPLYYENR----- 662
A L+ + EA +Y +A+ DL ++++ L+Y +R
Sbjct: 717 DDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFA 776
Query: 663 -------------------SAWIRMMKESIMSIAPRFSTYRMVKEYISKFYS 695
AW M+ ++I + + +FS+ R +KEY ++
Sbjct: 777 DYEAYVKCQDKVSQLYMNPKAWNTMVLKNI-AASGKFSSDRTIKEYAQNIWN 827
>gb|AAC18079.1| (AF046798) glycogen phosphorylase [Homo sapiens]
>gi|3219697|gb|AAC23504.1| (AF046785) liver glycogen
phosphorylase [Homo sapiens]
Length = 847
Score = 85.0 bits (207), Expect = 3e-15
Identities = 120/509 (23%), Positives = 205/509 (39%), Gaps = 103/509 (20%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ A E +R F++ + L + +A EL + T +T HT +P + +PVD V +
Sbjct: 336 IQLNDTHPALAIPELMRIFVDIEKLPWSKAWELNQKTFAYTNHTVLPEALERWPVDLVEK 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L + + L ++ P+D + NM L I S VN
Sbjct: 396 LLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKRINMAHLCIVGSHAVNG 455
Query: 374 VSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIWR 430
V+K+H+ + + + + D+ TNG+ W+ N LA+L IG+ +
Sbjct: 456 VAKIHSDIVKTKVFKDFSELEPDKFQNK--TNGITPRRWLLLCNPGLAELIAEKIGEDYV 513
Query: 431 EHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNE----RLGIDEPLPDID 486
+ + S+L + H +V K+ + N+ + E I+
Sbjct: 514 KDL--------------SQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYKVKIN 559
Query: 487 ENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKE 542
+++ +R YKR +L + T R+K+ P +I GGKA P K
Sbjct: 560 PSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPKKLFVPRTVIIGGKAAPGYHMAKM 619
Query: 543 FLRRVYEVSQ------MPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSG 596
++ + V+ M K K+I +ENY + A ++ D+ EASGT
Sbjct: 620 IIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGN 679
Query: 597 MKAGLNGVINLSVFDGWWVEGYNGRN-------GWVIGD-ATLEPE-TEADDYLDAM--- 644
MK LNG + + DG VE G I D A L+ + EA +Y +A+
Sbjct: 680 MKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMSIDDVAALDKKGYEAKEYYEALPEL 739
Query: 645 --------------SLYDLLENVVVPLYYENR------------------------SAWI 666
DL ++++ L+Y +R AW
Sbjct: 740 KLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFADYEAYVKCQDKVSQLYMNPKAWN 799
Query: 667 RMMKESIMSIAPRFSTYRMVKEYISKFYS 695
M+ ++I + + +FS+ R +KEY ++
Sbjct: 800 TMVLKNI-AASGKFSSDRTIKEYAQNIWN 827
>pir||A25518 glycogen phosphorylase (EC 2.4.1.1), hepatic - human
>gi|183353|gb|AAA52577.1| (M14636) glycogen
phosphorylase (EC 2.4.1.1) [Homo sapiens]
Length = 847
Score = 84.3 bits (205), Expect = 5e-15
Identities = 120/509 (23%), Positives = 204/509 (39%), Gaps = 103/509 (20%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP A E +R F++ + L + +A EL + T +T HT +P + +PVD V +
Sbjct: 336 IQLNDTHPRIAIPELMRIFVDIEKLPWSKAWELNQKTFAYTNHTVLPEALERWPVDLVEK 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L + + L ++ P+D + NM L I S VN
Sbjct: 396 LLPRHLEIIYEINQKHLDRIVALFPKDVDPLRRMSLIEEEGSKRINMAHLCIVGSHAVNG 455
Query: 374 VSKLHAKVTREMWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIWR 430
V+K+H+ + + + + D+ TNG+ W+ N LA+L IG+ +
Sbjct: 456 VAKIHSDIVKTKVFKDFSELEPDKFQNK--TNGITPRRWLLLCNPGLAELIAEKIGEDYV 513
Query: 431 EHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNE----RLGIDEPLPDID 486
+ + S+L + H +V K+ + N+ + E I+
Sbjct: 514 KDL--------------SQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYKVKIN 559
Query: 487 ENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKE 542
+++ +R YKR +L + T R+K+ P +I GGKA P K
Sbjct: 560 PSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPKKLFVPRTVIIGGKAAPGYHMAKM 619
Query: 543 FLRRVYEVSQ------MPEFKGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSG 596
++ + V+ M K K+I +ENY + A ++ D+ EASGT
Sbjct: 620 IIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGN 679
Query: 597 MKAGLNGVINLSVFDGWWVEGYNGRN-------GWVIGD-ATLEPE-TEADDYLDAM--- 644
MK LNG + + DG VE G I D A L+ + EA +Y +A+
Sbjct: 680 MKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMSIDDVAALDKKGYEAKEYYEALPEL 739
Query: 645 --------------SLYDLLENVVVPLYYENR------------------------SAWI 666
DL ++++ L+Y +R AW
Sbjct: 740 KLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFADYEAYVKCQDKVSQLYMNPKAWN 799
Query: 667 RMMKESIMSIAPRFSTYRMVKEYISKFYS 695
M+ ++I + + +FS+ R +KEY ++
Sbjct: 800 TMVLKNI-AASGKFSSDRTIKEYAQNIWN 827
>gb|AAB68800.1| (AF001899) glycogen myophosphorylase [Ovis aries]
Length = 842
Score = 83.1 bits (202), Expect = 1e-14
Identities = 132/578 (22%), Positives = 227/578 (38%), Gaps = 99/578 (17%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEID------------RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y+ G F Q+I R G EK
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEADDWLRYGNPWEKA 193
Query: 174 -PEYNI------REMPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVE------------- 213
PE+ + R Q T +++ +P + + R +V
Sbjct: 194 RPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDF 253
Query: 214 ------VGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM----RLL 263
VG +LD ++ EN D + + + R+KQE + + R
Sbjct: 254 NLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIIRRF 312
Query: 264 KALEI--------------EPGVIHLNEGHPSFANFERIRWFMEKG-LTFEEALELVRAT 308
K+ + + I LN+ HPS A E +R +++ L +E+A E+ T
Sbjct: 313 KSSKFGCLDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDQERLEWEKAWEVTVKT 372
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PV + L L+ + + L +V P D +
Sbjct: 373 CAYTNHTVLPEALERWPVHLIETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLV 432
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHT 409
NM L I S VN V+++H+++ ++ ++ + + P TNG+
Sbjct: 433 EEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHK---FQNKTNGITP 489
Query: 410 PTWVNENLAKLYDIYIGKIWREHV-NLEGIWYAIERIPDSELWEAHLKAKREVIELIRRK 468
W+ L ++ +I E++ +L+ + + + D K K+E + K
Sbjct: 490 RRWLVMCNPGLAEVIAERIGEEYIADLDQLRKLLSYVDDESFIRDVAKVKQEN----KLK 545
Query: 469 IMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERP 524
E+ E I+ N+L +R YKR +L + T R+K+ N P
Sbjct: 546 FSAYLEK----EYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFFVP 601
Query: 525 VYIIFGGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGV 578
++ GGKA P K +R + + + + ++I +ENY + A ++
Sbjct: 602 RTVMIGGKAAPGYHMAKMIIRLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAA 661
Query: 579 DVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
D+ EASGT MK LNG + + DG VE
Sbjct: 662 DLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVE 699
>pir||S77252 phosphorylase (EC 2.4.1.1) 2 - Synechocystis sp. (strain PCC 6803)
>gi|1652666|dbj|BAA17586.1| (D90907) glycogen
phosphorylase [Synechocystis sp.]
Length = 855
Score = 82.7 bits (201), Expect = 2e-14
Identities = 96/381 (25%), Positives = 162/381 (42%), Gaps = 54/381 (14%)
Query: 273 IHLNEGHPSFANFERIRWFMEK-GLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ A E +R F+++ +++A ++ + T +T HT +P + + VD +
Sbjct: 346 IQLNDTHPAVAIAELMRLFVDRYDYDWDKAWDITQKTFAYTNHTLMPEALERWSVDLFAK 405
Query: 332 KLRLFLRDLPQ--DKFL-GLGKVTPEDT---------------NFNMTVLSIRTSEFVNA 373
L L + + +FL GL P D M L+ S +N
Sbjct: 406 LLPRHLEIIYEINHRFLTGLQTWFPNDEALVESLSLIEENHGKKIRMANLACVGSHAING 465
Query: 374 VSKLHAKV----TREMWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
V+ LH ++ T ++ LWP ++ TNGV W+ N L+ L IG
Sbjct: 466 VAALHTELLKKDTLRDFAKLWPQKFFNK------TNGVTPRRWILLSNPELSALVTEKIG 519
Query: 427 KIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMK-RNERLGIDEPLPDI 485
W + NL+ + + + D E + K+ + ++K RN + I
Sbjct: 520 DGWLK--NLDEMRQIEKFVDDPEFCRRWREIKQNNKRNLAAYLLKYRNVQ---------I 568
Query: 486 DENALIIGFARRFATYKRAILLFTDLERL-KRIVNNPER---PVYIIFGGKAHPMDEAGK 541
D N+L +R YKR L ++ L RI NP P IFGGKA P K
Sbjct: 569 DVNSLFDVQVKRIHEYKRQHLAALEIIHLYNRIKQNPHAEIVPRTFIFGGKAAPGYFMAK 628
Query: 542 EFLRRVYEVSQM----PEFKG--KIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTS 595
++ + V ++ P+ +G K++ + N+++ + + D+ EASGT
Sbjct: 629 LIIKLINAVGEVVNNDPDVRGRLKVVFVSNFNVSLGQRIYPAADLSEQISTAGKEASGTG 688
Query: 596 GMKAGLNGVINLSVFDGWWVE 616
MK +NG + + DG +E
Sbjct: 689 NMKFAMNGALTIGTLDGANIE 709
>prf||0401194A phosphorylase b,glycogen [Oryctolagus cuniculus]
Length = 841
Score = 82.3 bits (200), Expect = 2e-14
Identities = 130/577 (22%), Positives = 230/577 (39%), Gaps = 98/577 (16%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEID------------RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y+ G F Q+I R G EK
Sbjct: 133 NGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKA 192
Query: 174 -PEYNI------REMPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVE------------- 213
PE+ + R Q T +++ +P + + R +V
Sbjct: 193 RPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDF 252
Query: 214 ------VGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGMRLLKALE 267
VG +LD ++ EN D + + + R+KQE + ++ ++ +
Sbjct: 253 NLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIRRFK 311
Query: 268 I-----------------EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATS 309
+ I LN+ HPS A E +R ++ + L +++A E+ T
Sbjct: 312 SSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTC 371
Query: 310 VFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN--------- 357
+T HT +P + +PV + L L+ + + L +V P D +
Sbjct: 372 AYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVE 431
Query: 358 ------FNMTVLSIRTSEFVNAVSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTP 410
NM L I S VN V+++H+++ ++ ++ + + P TNG+
Sbjct: 432 EGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPR 488
Query: 411 TWVNENLAKLYDIYIGKIWREHVN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKI 469
W+ L +I +I E+++ L+ + + + D EA ++ +V + + K
Sbjct: 489 RWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKF 544
Query: 470 MKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPV 525
ER E I+ N+L +R YKR +L + T R+K+ N P
Sbjct: 545 AAYLER----EYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPR 600
Query: 526 YIIFGGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVD 579
++ GGKA P K ++ + + + + ++I +ENY + A ++ D
Sbjct: 601 TVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAAD 660
Query: 580 VWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
+ EASGT MK LNG + + DG VE
Sbjct: 661 LSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVE 697
>gb|AAB46846.1| (S82859) alpha-1,4-glucan orthophosphate glycosyl transferase,
myophosphorylase, glycogen phosphorylase isozyme
[cattle, skeletal muscle, Peptide, 842 aa] [Bos taurus]
>gi|1589006|prf||2209429A myophosphorylase [Bos taurus]
Length = 842
Score = 82.3 bits (200), Expect = 2e-14
Identities = 132/578 (22%), Positives = 227/578 (38%), Gaps = 99/578 (17%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEID------------RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y+ G F Q+I R G EK
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEADDWLRYGNPWEKA 193
Query: 174 -PEYNI------REMPIRQVLNNDGTPLLIDVPIEDRIVKARVFLVE------------- 213
PE+ + R Q T +++ +P + + R +V
Sbjct: 194 RPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDF 253
Query: 214 ------VGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGM----RLL 263
VG +LD ++ EN D + + + R+KQE + + R
Sbjct: 254 NLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIIRRF 312
Query: 264 KALEI--------------EPGVIHLNEGHPSFANFERIRWFMEKG-LTFEEALELVRAT 308
K+ + + I LN+ HPS A E +R +++ L +E+A E+ T
Sbjct: 313 KSSKFGCLDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDQERLEWEKAWEVTVKT 372
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PV + L L+ + + L +V P D +
Sbjct: 373 CAYTNHTVLPEALERWPVHLIETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLV 432
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHT 409
NM L I S VN V+++H+++ ++ ++ + + P TNG+
Sbjct: 433 EEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHK---FQNKTNGITP 489
Query: 410 PTWVNENLAKLYDIYIGKIWREHV-NLEGIWYAIERIPDSELWEAHLKAKREVIELIRRK 468
W+ L +I +I E++ +L+ + + + D K K+E + K
Sbjct: 490 RRWLVMCNPGLAEIIAERIGEEYIADLDQLRKLLSYVDDESFIRDVAKVKQEN----KLK 545
Query: 469 IMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERP 524
E+ E I+ N+L +R YKR +L + T R+K+ N P
Sbjct: 546 FSAYLEK----EYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFFVP 601
Query: 525 VYIIFGGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGV 578
++ GGKA P K ++ + + + + ++I +ENY + A ++
Sbjct: 602 RTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAA 661
Query: 579 DVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
D+ EASGT MK LNG + + DG VE
Sbjct: 662 DLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVE 699
>sp|P34114|PHS2_DICDI GLYCOGEN PHOSPHORYLASE 2 (GP2) >gi|283457|pir||A42318 glycogen
phosphorylase (EC 2.4.1.1) 2 - slime mold
(Dictyostelium discoideum) >gi|167802|gb|AAA33211.1|
(M77492) glycogen phosphorylase 2 [Dictyostelium
discoideum]
Length = 992
Score = 81.5 bits (198), Expect = 3e-14
Identities = 128/582 (21%), Positives = 232/582 (38%), Gaps = 112/582 (19%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKFPE--------YN 177
+GGLG LA + + + P GL YK G F Q + DG Q+E P+ +
Sbjct: 220 NGGLGRLAACFMDSLATCNFPGYGYGLRYKFGMFYQTLV-DGEQVE-LPDLWLNYGSPWE 277
Query: 178 IREMPIRQVLNNDGTPLLIDVPIEDRIVK--------ARVFLVEVGRVKLYL-------- 221
I + + +N G ++ +++K A + + K Y
Sbjct: 278 IERLDVSYPINFYGKVSEVEDENGKKVMKWDQGEQMLAIAYDYPIPGFKTYNTVAIRLWS 337
Query: 222 --------LDT-------DVPENREDDRRICDYLYNAE-----PDKRIKQEILIGIGGMR 261
LD+ E +E I + LY + + R+KQ+ L ++
Sbjct: 338 SKPSDEFNLDSFNRGDYLGAIEEKEKSENITNVLYPNDNTMQGKELRLKQQYLFVSATIQ 397
Query: 262 LLKALEIEPG---------VIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVF 311
+ + E G I LN+ HP+ E +R + E+ +++EA ++ T +
Sbjct: 398 DIISQFKETGKPFSEFTFHAIQLNDTHPTLGIPELMRILIDEEKKSWDEAWDITTKTFSY 457
Query: 312 TTHTPVPAGHDVFPVDFVREKL-----------RLFLRDLPQ------DKFLGLGKVTPE 354
T HT +P + + V V L FL+ + Q K L +
Sbjct: 458 TNHTVLPEALEKWSVSMVENVLPRHIMIIYEINERFLKLVDQKWPGDMSKRRALSIIDES 517
Query: 355 DTNFN-MTVLSIRTSEFVNAVSKLHAKVTRE----MWSNLWPGVPTDEIPIDAITNGVHT 409
D F M L+I + +N V+ LH+++ + ++ +WP + T+GV
Sbjct: 518 DGKFIVMAFLAIVGAHTINGVAYLHSELVKHDVFPLFYEVWPN------KFQSKTSGVTP 571
Query: 410 PTWVNENLAKLYDIYIGKIWREH--VNLEGIWYAIERIPDSELWEAHLKAKREVIELIRR 467
+W+ ++ +L ++ + + VNL+ I + +S + + R + +
Sbjct: 572 SSWIEQSNPQLAELITRSLNSDRWLVNLDIIKDLVHLADNSSFQKEWMTINRNNKIRLAK 631
Query: 468 KIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL-------LFTDLERLKRIVNN 520
I KR + + L D+ +RF YKR +L + D++ K++
Sbjct: 632 YIEKRCDIQVNVDVLFDVQ--------VKRFHEYKRQLLNVLSVINRYLDIKEGKKVA-- 681
Query: 521 PERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQM----PEFKG--KIILIENYDMGSARIL 574
P +IFGGKA P K ++ + V+ + P+ K++ I NY + +A I+
Sbjct: 682 ---PRVVIFGGKAAPGYYMAKLIIKLINSVADVVNNDPKVGDLLKVVFIPNYCVSNAEII 738
Query: 575 VSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
+ D+ + EASGTS MK +NG + + DG +E
Sbjct: 739 IPASDISQHISTAGTEASGTSNMKFSMNGGLIIGTLDGANIE 780
>gb|AAD03471.1| (AF033856) glycogen phosphorylase [Agrobacterium tumefaciens]
Length = 821
Score = 81.1 bits (197), Expect = 5e-14
Identities = 98/399 (24%), Positives = 172/399 (42%), Gaps = 46/399 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ + E IR + GL F+EA + + T +T HT +P + +PV +
Sbjct: 329 IQLNDTHPAISICEMIRLLCDVHGLEFDEAWRITQGTFSYTNHTLLPEALESWPVPLLER 388
Query: 332 KLR--------------LFLRDLPQDKFLGLGKVTPEDTNFNMTV----LSIRTSEFVNA 373
L LF R + + ++ D V L+ S +N
Sbjct: 389 LLPRHMQIVYAINANTLLFARKEKKMADQQIRSISLIDEGGERRVRMGNLAFIGSHSING 448
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
VS LH ++ +E ++++L P I+ TNG+ W+ + L + I +
Sbjct: 449 VSALHTELMKETVFADLHSLYPER---INNKTNGITPRRWLMQCNPGLTGLIREAIGDDF 505
Query: 433 VNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRN--ERLGIDEPLPDIDENAL 490
++ A++R D +A + K ++ + + + +R+G+ +D +A+
Sbjct: 506 LDDAEKLIALDRFAD----DAGFREKFAEVKRLNKVRLANTVAQRMGLR-----VDPSAM 556
Query: 491 IIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAGKEFLRR 546
+R YKR +L L + +I ++PE P F GKA P K ++
Sbjct: 557 FDIQIKRIHEYKRQLLNLIETVALYDQIRSHPELDWVPRVKFFAGKAAPSYHNAKLIIKL 616
Query: 547 VYEVSQM----PEFKG--KIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAG 600
+++++ P +G K++ I NY++ A I+V D+ +EASGT MK
Sbjct: 617 ANDIARVINNDPAVRGLLKVVFIPNYNVSLAEIMVPAADLSEQISTAGMEASGTGNMKFA 676
Query: 601 LNGVINLSVFDGWWVE--GYNGRNGWVIGDATLEPETEA 637
LNG + + DG VE + G + VI T E + A
Sbjct: 677 LNGALTIGTLDGANVEMLEHVGADNIVIFGMTAEEVSRA 715
>prf||1402394A glycogen phosphorylase [Homo sapiens]
Length = 842
Score = 81.1 bits (197), Expect = 5e-14
Identities = 133/580 (22%), Positives = 232/580 (39%), Gaps = 103/580 (17%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEID------------RDGRQIEKF 173
+GGLG LA L + + LGL G+ Y+ G F Q+I R G EK
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEADDWLRYGNPWEKA 193
Query: 174 -PEYNIREMPIRQVLNND------GTPLLIDVPIEDRIVKARVFLVE------------- 213
PE+ + V + T +++ +P + + R +V
Sbjct: 194 RPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDF 253
Query: 214 ------VGRVKLYLLDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGGMR--LLKA 265
VG +LD ++ EN D + + + R+KQE + ++ + +
Sbjct: 254 NLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFVVAATLQDIIRRF 312
Query: 266 LEIEPG----------------VIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRAT 308
+PG I LN+ HPS A E +R ++ + + +++A ++ T
Sbjct: 313 KSSKPGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERMDWDKAWDVTVRT 372
Query: 309 SVFTTHTPVPAGHDVFPVDFVREKLRLFLRDLPQDKFLGLGKVT---PEDTN-------- 357
+T HT +P + +PV + L L+ + + L +V P D +
Sbjct: 373 CAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLV 432
Query: 358 -------FNMTVLSIRTSEFVNAVSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHT 409
NM L I S VN V+++H+++ ++ ++ + + P TNG+
Sbjct: 433 EEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHK---FQNKTNGITP 489
Query: 410 PTWV---NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIR 466
W+ N LA++ IG+ + +L+ + + + D EA ++ +V + +
Sbjct: 490 RRWLVLCNPGLAEVIAERIGEDFIS--DLDQLRKLLSFVDD----EAFIRDVAKVKQENK 543
Query: 467 RKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVNNPE 522
K ER E I+ N+L +R YKR +L + T R+KR N
Sbjct: 544 LKFAAYLER----EYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFF 599
Query: 523 RPVYIIFGGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVS 576
P ++ GGKA P K +R V + + + ++I +ENY + A ++
Sbjct: 600 VPRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIP 659
Query: 577 GVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
D+ EASGT MK LNG + + DG VE
Sbjct: 660 AADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVE 699
>pdb|1C8K|A Chain A, Flavopiridol Inhibits Glycogen Phosphorylase By Binding At
The Inhibitor Site >gi|9955129|pdb|1GFZ|A Chain A,
Flavopiridol Inhibits Glycogen Phosphorylase By Binding
At The Inhibitor Site >gi|10120835|pdb|1GG8|A Chain A,
Design Of Inhibitors Of Glycogen Phosphorylase: A Study
Of Alpha-And Beta-C-Glucosides And 1-Thio-Beta-D-Glucose
Compounds >gi|10835439|pdb|1FS4|A Chain A, Structures Of
Glycogen Phosphorylase-Inhibitor Complexes And The
Implications For Structure-Based Drug Design
>gi|10835441|pdb|1FTQ|A Chain A, Structures Of Glycogen
Phosphorylase-Inhibitor Complexes And The Implications
For Structure-Based Drug Design >gi|10835442|pdb|1FTW|A
Chain A, Structures Of Glycogen Phosphorylase-Inhibitor
Complexes And The Implications For Structure-Based Drug
Design >gi|10835443|pdb|1FTY|A Chain A, Structures Of
Glycogen Phosphorylase-Inhibitor Complexes And The
Implications For Structure-Based Drug Design
>gi|10835444|pdb|1FU4|A Chain A, Structures Of Glycogen
Phosphorylase-Inhibitor Complexes And The Implications
For Structure-Based Drug Design >gi|10835445|pdb|1FU7|A
Chain A, Structures Of Glycogen Phosphorylase-Inhibitor
Complexes And The Implications For Structure-Based Drug
Design >gi|10835446|pdb|1FU8|A Chain A, Structures Of
Glycogen Phosphorylase-Inhibitor Complexes And The
Implications For Structure-Based Drug Design
>gi|10835850|pdb|1GGN|A Chain A, Structures Of Glycogen
Phosphorylase-Inhibitor Complexes And The Implications
For Structure-Based Drug Design >gi|231141|pdb|5GPB|
Glycogen Phosphorylase b (E.C.2.4.1.1) (T State) Complex
With Alpha-D-Glucose-1-Methylene-Phosphate And
Maltohexaose >gi|230866|pdb|3GPB| Glycogen
Phosphorylase b (E.C.2.4.1.1) (T State) Complex With
Alpha-D-Glucose-1-Phosphate >gi|231016|pdb|4GPB|
Glycogen Phosphorylase b (E.C.2.4.1.1) (T State) Complex
With 2-Fluoro-2-Deoxy-Alpha-D-Glucose-1-Phosphate
>gi|230542|pdb|2GPB| Glycogen Phosphorylase b
(E.C.2.4.1.1) (T State) Complex With Alpha-D-Glucose
>gi|6729833|pdb|2PRJ|A Chain A, Binding Of
2-Deoxy-Glucose-6-Phosphate To Glycogen Phosphorylase B
>gi|6729832|pdb|2PRI|A Chain A, Binding Of
2-Deoxy-Glucose-6-Phosphate To Glycogen Phosphorylase B
>gi|6729837|pdb|2SKC|A Chain A, Pyridoxal Phosphorylase
B In Complex With Fluorophosphate, Glucose And
Inosine-5'-Monophosphate >gi|6729838|pdb|2SKD|A Chain A,
Pyridoxal Phosphorylase B In Complex With Phosphate,
Glucose And Inosine-5'-Monophosphate
>gi|6729839|pdb|2SKE|A Chain A, Pyridoxal Phosphorylase
B In Complex With Phosphite, Glucose And
Inosine-5'-Monophosphate >gi|231213|pdb|6GPB| Glycogen
Phosphorylase b (E.C.2.4.1.1) (T State) Complex With
Heptulose 2-Phosphate And Maltoheptaose And AMP
>gi|229948|pdb|1GPA|A Chain A, Glycogen Phosphorylase a
(E.C.2.4.1.1) (R State) >gi|229950|pdb|1GPA|C Chain C,
Glycogen Phosphorylase a (E.C.2.4.1.1) (R State)
>gi|229951|pdb|1GPA|D Chain D, Glycogen Phosphorylase a
(E.C.2.4.1.1) (R State) >gi|229949|pdb|1GPA|B Chain B,
Glycogen Phosphorylase a (E.C.2.4.1.1) (R State)
>gi|231257|pdb|7GPB|A Chain A, Glycogen Phosphorylase b
(E.C.2.4.1.1) (R State) Complex With AMP
>gi|231258|pdb|7GPB|B Chain B, Glycogen Phosphorylase b
(E.C.2.4.1.1) (R State) Complex With AMP
>gi|231259|pdb|7GPB|C Chain C, Glycogen Phosphorylase b
(E.C.2.4.1.1) (R State) Complex With AMP
>gi|231260|pdb|7GPB|D Chain D, Glycogen Phosphorylase b
(E.C.2.4.1.1) (R State) Complex With AMP
>gi|231322|pdb|9GPB|A Chain A, Glycogen Phosphorylase b
(E.C.2.4.1.1) (R State) >gi|231323|pdb|9GPB|B Chain B,
Glycogen Phosphorylase b (E.C.2.4.1.1) (R State)
>gi|231325|pdb|9GPB|D Chain D, Glycogen Phosphorylase b
(E.C.2.4.1.1) (R State) >gi|231324|pdb|9GPB|C Chain C,
Glycogen Phosphorylase b (E.C.2.4.1.1) (R State)
>gi|229952|pdb|1GPB| Glycogen Phosphorylase b
(E.C.2.4.1.1) (T State) >gi|6729697|pdb|1B4D|A Chain A,
Amidocarbamate Inhibitor Of Glycogen Phosphorylase
>gi|6729759|pdb|1BX3|A Chain A, Effects Of Commonly Used
Cryoprotectants On Glycogen Phosphorylase Activity And
Structure
Length = 842
Score = 80.4 bits (195), Expect = 8e-14
Identities = 91/375 (24%), Positives = 162/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 335 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLET 394
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 395 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 454
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 455 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 511
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 512 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 563
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 564 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 623
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 624 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 683
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 684 NGALTIGTMDGANVE 698
>pdb|8GPB| Glycogen Phosphorylase b (E.C.2.4.1.1) (T State) Complex With AMP
Length = 832
Score = 80.4 bits (195), Expect = 8e-14
Identities = 91/375 (24%), Positives = 162/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 325 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLET 384
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 385 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 444
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 445 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 501
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 502 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 553
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 554 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 613
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 614 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 673
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 674 NGALTIGTMDGANVE 688
>pdb|1ABB|A Chain A, Glycogen Phosphorylase (E.C.2.4.1.1) Complex With
Pyridoxal-5'-Diphosphate >gi|442606|pdb|1ABB|B Chain B,
Glycogen Phosphorylase (E.C.2.4.1.1) Complex With
Pyridoxal-5'-Diphosphate >gi|442607|pdb|1ABB|C Chain C,
Glycogen Phosphorylase (E.C.2.4.1.1) Complex With
Pyridoxal-5'-Diphosphate >gi|442608|pdb|1ABB|D Chain D,
Glycogen Phosphorylase (E.C.2.4.1.1) Complex With
Pyridoxal-5'-Diphosphate
Length = 828
Score = 80.4 bits (195), Expect = 8e-14
Identities = 91/375 (24%), Positives = 162/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 326 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLET 385
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 386 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 445
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 446 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 502
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 503 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 554
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 555 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 614
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 615 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 674
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 675 NGALTIGTMDGANVE 689
>pdb|1C50|A Chain A, Identification And Structural Characterization Of A Novel
Allosteric Binding Site Of Glycogen Phosphorylase B
Length = 830
Score = 80.4 bits (195), Expect = 8e-14
Identities = 91/375 (24%), Positives = 162/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 323 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLET 382
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 383 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 442
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 443 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 499
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 500 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 551
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 552 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 611
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 612 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 671
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 672 NGALTIGTMDGANVE 686
>sp|P00489|PHS2_RABIT GLYCOGEN PHOSPHORYLASE, MUSCLE FORM (MYOPHOSPHORYLASE)
>gi|90033|pir||A24302 glycogen phosphorylase (EC
2.4.1.1) - rabbit >gi|7427923|pir||PHRBG glycogen
phosphorylase (EC 2.4.1.1), muscle - rabbit
Length = 843
Score = 79.6 bits (193), Expect = 1e-13
Identities = 91/375 (24%), Positives = 162/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLET 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 396 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 456 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 512
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 513 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 564
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 565 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 624
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 625 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 684
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 685 NGALTIGTMDGANVE 699
>prf||1103304A phosphorylase,maltodextrin [Escherichia coli]
Length = 688
Score = 79.6 bits (193), Expect = 1e-13
Identities = 95/382 (24%), Positives = 157/382 (40%), Gaps = 57/382 (14%)
Query: 272 VIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVR 330
VI LN+ HP+ A E +R + E +++++A + T +T HT +P + + V V+
Sbjct: 303 VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVK 362
Query: 331 EKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVS 375
L L + P D+ + D +M L + VN V+
Sbjct: 363 GLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHMANLCVVGGFAVNGVA 422
Query: 376 KLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKI 428
LH+ V +++ + LWP +TNG+ W+ N LA L D + K
Sbjct: 423 ALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQCNPALAALLDKSLQKE 476
Query: 429 WREHVNLEGIWYAIERIPDSELWEAHLKAKR----EVIELIRRKIMKRNERLGIDEPLPD 484
W +L+ + ++ D++ E + K+ + E ++ R GID
Sbjct: 477 WAN--DLDQLINLVKLADDAKFRELYRVIKQANKVRLAEFVK-------VRTGID----- 522
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
I+ A+ +R YKR L L L K I NP+ P +FG KA P
Sbjct: 523 INPQAIFDIQIKRLHEYKRQHLNLLRILALYKEIRQNPQADRVPRVFLFGAKAAPGYYLA 582
Query: 541 KEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+ + K K++ + +Y + +A L+ D+ EASGT
Sbjct: 583 KNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASGT 642
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG VE
Sbjct: 643 GNMKLALNGALTVGTLDGANVE 664
>pdb|1E1Y|A Chain A, Lavopiridol Inhibits Glycogen Phosphorylase By Binding At
The Inhibitor Site >gi|2914396|pdb|1AXR| Cooperativity
Between Hydrogen-Bonding And Charge-Dipole Interactions
In The Inhibition Of Beta-Glycosidases By
Azolopyridines: Evidence From A Study With Glycogen
Phosphorylase B >gi|6729822|pdb|2AMV|A Chain A, The
Structure Of Glycogen Phosphorylase B With An Alkyl-
Dihydropyridine-Dicarboxylic Acid >gi|442964|pdb|1GPY|
Glycogen Phosphorylase B (E.C.2.4.1.1) (T State) Complex
With Alpha-D-Glucose-6-Phosphate >gi|4558003|pdb|2GPA|A
Chain A, Allosteric Inhibition Of Glycogen Phosphorylase
A By A Potential Antidiabetic Drug
>gi|4558004|pdb|3AMV|A Chain A, Allosteric Inhibition Of
Glycogen Phosphorylase A By A Potential Antidiabetic
Drug >gi|494494|pdb|1PYG|A Chain A, Glycogen
Phosphorylase B (Pyridoxal-5'-Pyrophosphoryl Derivative)
(E.C.2.4.1.1) Complex With Adenosine Monophosphate
>gi|494496|pdb|1PYG|C Chain C, Glycogen Phosphorylase B
(Pyridoxal-5'-Pyrophosphoryl Derivative) (E.C.2.4.1.1)
Complex With Adenosine Monophosphate
>gi|494497|pdb|1PYG|D Chain D, Glycogen Phosphorylase B
(Pyridoxal-5'-Pyrophosphoryl Derivative) (E.C.2.4.1.1)
Complex With Adenosine Monophosphate
>gi|494495|pdb|1PYG|B Chain B, Glycogen Phosphorylase B
(Pyridoxal-5'-Pyrophosphoryl Derivative) (E.C.2.4.1.1)
Complex With Adenosine Monophosphate
Length = 842
Score = 79.6 bits (193), Expect = 1e-13
Identities = 91/375 (24%), Positives = 162/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 335 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLET 394
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 395 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 454
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 455 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 511
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 512 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 563
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 564 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 623
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 624 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 683
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 684 NGALTIGTMDGANVE 698
>sp|Q9Z8N1|PHSG_CHLPN GLYCOGEN PHOSPHORYLASE >gi|7433827|pir||C72095 phosphorylase (EC
2.4.1.1) CP0451 [similarity] - Chlamydophila pneumoniae
(strains CWL029 and AR39) >gi|4376583|gb|AAD18456.1|
(AE001615) Glycogen Phosphorylase [Chlamydophila
pneumoniae CWL029] >gi|7189373|gb|AAF38289.1| (AE002205)
glycogen phosphorylase [Chlamydophila pneumoniae AR39]
>gi|8978681|dbj|BAA98517.1| (AP002546) glycogen
phosphorylase [Chlamydophila pneumoniae J138]
Length = 824
Score = 79.6 bits (193), Expect = 1e-13
Identities = 90/382 (23%), Positives = 157/382 (40%), Gaps = 54/382 (14%)
Query: 272 VIHLNEGHPSFANFERIRWFMEKG-LTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVR 330
V+ LN+ HP+ E + +++ L +++A E+ +T HT +P + +P+D
Sbjct: 321 VVQLNDTHPALGIAEMMHILVDREELPWDKAWEMTTVIFNYTNHTILPEALERWPLDLFS 380
Query: 331 EKLRLFLRDLPQDKFLGLGKVTPE------------------DTNFNMTVLSIRTSEFVN 372
+ L L + + L KV NM L++ S VN
Sbjct: 381 KLLPRHLEIIYEINSRWLEKVGSRYPKNDDKRRSLSIVEEGYQKRINMANLAVVGSAKVN 440
Query: 373 AVSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKI 428
VS H+++ ++ ++ + P I + TNGV W+ N L+KL + IG
Sbjct: 441 GVSSFHSQLIKDTLFKEFYEFFPEKFINV---TNGVTPRRWIALCNPRLSKLLNETIGD- 496
Query: 429 WREHVNLEGIWYAIERIPDS---ELWEA-HLKAKREVIELIRRKIMKRNERLGIDEPLPD 484
R ++L + DS + W+ LK K+++ I ++ +
Sbjct: 497 -RYIIDLSHLSLIRSFAEDSGFRDHWKGVKLKNKQDLTSRIYNEVGEI------------ 543
Query: 485 IDENALIIGFARRFATYKRAILLFTDL----ERLKRIVNNPERPVYIIFGGKAHPMDEAG 540
+D N+L +R YKR ++ + LK N P +IF GKA P
Sbjct: 544 VDPNSLFDCHIKRIHEYKRQLMNILRVIYVYNDLKENPNQDVVPTTVIFSGKAAPGYVMA 603
Query: 541 KEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K ++ + V+ + K K++ + NY + A ++ G D+ +EASGT
Sbjct: 604 KLIIKLINSVADVVNQDSRVNDKLKVLFLPNYRVSMAEHIIPGTDLSEQISTAGMEASGT 663
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG +E
Sbjct: 664 GNMKFALNGALTIGTMDGANIE 685
>pdb|1C8L|A Chain A, Synergistic Inhibition Of Glycogen Phosphorylase A By A
Potential Antidiabetic Drug And Caffeine
Length = 842
Score = 79.6 bits (193), Expect = 1e-13
Identities = 91/375 (24%), Positives = 162/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 335 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLET 394
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 395 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 454
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 455 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 511
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 512 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 563
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 564 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 623
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 624 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 683
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 684 NGALTIGTMDGANVE 698
>gb|AAD53957.1|AF181035_1 (AF181035) glycogen phosphorylase [Rhodobacter sphaeroides]
Length = 519
Score = 79.6 bits (193), Expect = 1e-13
Identities = 113/418 (27%), Positives = 178/418 (42%), Gaps = 56/418 (13%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHD--------- 322
I +N+ HP+ A E IR + E GL+F+EAL + + +T HT +P +
Sbjct: 31 IQMNDTHPAIAGPELIRLLVDEHGLSFDEALPVAQECLGYTNHTLLPEALERWATFTFGN 90
Query: 323 VFP--VDFVREKLRLFLRDLP-QDKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVSKLHA 379
V P + V R P + ++G+ K M L+ S VN VS LH
Sbjct: 91 VLPRHMQIVERIDGWHRRTFPARPHYVGIVK----HHEVRMGELAFIMSHKVNGVSALHT 146
Query: 380 KVTREMWSNLWPGVPTDEIPIDAI---TNGVHTPTWV---NENLAKLYDIYIGKIWREHV 433
+ + +NL+P + D + + I TNGV W+ N LA+L IG+ W + +
Sbjct: 147 DLVK---ANLFPEL--DRLHPEKIVNQTNGVTPRRWLKMANAPLARLIGETIGEGWEDDL 201
Query: 434 N-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALII 492
+ L+G+ + D A AKR+ K+ N LG + + + +AL
Sbjct: 202 DRLKGLE---PHVKDQGFLGAFDAAKRQ------NKVTLSNW-LGAECGVK-VSPDALFD 250
Query: 493 GFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAGKEFLRRVY 548
+R YKR +L + + R + I NP+ P IFGGK+ P KE + +
Sbjct: 251 VQVKRIHEYKRQLLNILETVARWQAIRANPDAGWVPRVKIFGGKSAPGYAVAKEIIHLIN 310
Query: 549 EVSQMPEFKG------KIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGLN 602
+V+ + K+I NY++ A LV D+ EASGT MK +N
Sbjct: 311 DVAAVINADPLVGDLLKVIYPANYNVSMAERLVPAADLSEQISTAGKEASGTGNMKFMMN 370
Query: 603 GVINLSVFDGWWVEGYN--GRNGWVIGDATLEP----ETEADDYLDAMSLYDLLENVV 654
G + DG VE GR + + T E + D A+ +++NV+
Sbjct: 371 GAPTIGTLDGANVEILQEVGRENFFLFGLTAEEVMKRREDPDHARKAIEASQIMQNVL 428
>pir||S34624 glycogen phosphorylase (EC 2.4.1.1), muscle - rat (fragment)
>gi|204423|gb|AAA41253.1| (L10669) glycogen
phosphorylase [Rattus norvegicus]
Length = 841
Score = 79.2 bits (192), Expect = 2e-13
Identities = 90/375 (24%), Positives = 160/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E IR ++ + L +++A ++ T +T HT +P + +PV +
Sbjct: 335 IQLNDTHPSLAIPELIRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMET 394
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 395 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 454
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L ++ +I E+
Sbjct: 455 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEVIAERIGEEY 511
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D K K+E +K + L + + I+ N+L
Sbjct: 512 ISDLDQLRKLLSYLDDQAFIRDVAKVKQE-------NKLKFSAYLETEYKV-HINPNSLF 563
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+KR N P I+ GGKA P K ++ +
Sbjct: 564 DVQVKRIHEYKRQLLNCLHIITLYNRIKREPNRFMVPRTIMIGGKAAPGYHMAKMIIKLI 623
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 624 TAIGDVVNHDPAVGDRFRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 683
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 684 NGALTIGTMDGANVE 698
>gb|AAA58215.1| (U18997) maltodextrin phosphorylase [Escherichia coli]
Length = 797
Score = 79.2 bits (192), Expect = 2e-13
Identities = 95/393 (24%), Positives = 162/393 (41%), Gaps = 51/393 (12%)
Query: 257 IGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHT 315
+ G +L + + E VI LN+ HP+ A E +R + E +++++A + T +T HT
Sbjct: 290 LAGRKLHELADYE--VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHT 347
Query: 316 PVPAGHDVFPVDFVREKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNM 360
+P + + V V+ L L + P D+ + D +M
Sbjct: 348 LMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHM 407
Query: 361 TVLSIRTSEFVNAVSKLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV--- 413
L + VN V+ LH+ V +++ + LWP +TNG+ W+
Sbjct: 408 ANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQC 461
Query: 414 NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRN 473
N LA L D + K W ++ +E+ D + + ++ ++ + +K
Sbjct: 462 NPALAALLDKSLQKEWANDLDQ---LINLEKFADDAKFRQQYREIKQANKVRLAEFVK-- 516
Query: 474 ERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIF 529
R GI+ I+ A+ +R YKR L L L K I NP+ P +F
Sbjct: 517 VRTGIE-----INPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVPRVFLF 571
Query: 530 GGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLN 583
G KA P K + + +V+ + K K++ + +Y + +A L+ D+
Sbjct: 572 GAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQ 631
Query: 584 TPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
EASGT MK LNG + + DG VE
Sbjct: 632 ISTAGKEASGTGNMKLALNGALTVGTLDGANVE 664
>sp|P09812|PHS2_RAT GLYCOGEN PHOSPHORYLASE, MUSCLE FORM (MYOPHOSPHORYLASE)
Length = 842
Score = 79.2 bits (192), Expect = 2e-13
Identities = 90/375 (24%), Positives = 160/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E IR ++ + L +++A ++ T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELIRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMET 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 396 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L ++ +I E+
Sbjct: 456 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEVIAERIGEEY 512
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D K K+E +K + L + + I+ N+L
Sbjct: 513 ISDLDQLRKLLSYLDDQAFIRDVAKVKQE-------NKLKFSAYLETEYKV-HINPNSLF 564
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+KR N P I+ GGKA P K ++ +
Sbjct: 565 DVQVKRIHEYKRQLLNCLHIITLYNRIKREPNRFMVPRTIMIGGKAAPGYHMAKMIIKLI 624
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 625 TAIGDVVNHDPAVGDRFRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 684
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 685 NGALTIGTMDGANVE 699
>pir||PHECGM phosphorylase (EC 2.4.1.1) malP - Escherichia coli
>gi|2367221|gb|AAC76442.1| (AE000417) maltodextrin
phosphorylase [Escherichia coli K12]
Length = 797
Score = 79.2 bits (192), Expect = 2e-13
Identities = 95/393 (24%), Positives = 162/393 (41%), Gaps = 51/393 (12%)
Query: 257 IGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHT 315
+ G +L + + E VI LN+ HP+ A E +R + E +++++A + T +T HT
Sbjct: 290 LAGRKLHELADYE--VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHT 347
Query: 316 PVPAGHDVFPVDFVREKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNM 360
+P + + V V+ L L + P D+ + D +M
Sbjct: 348 LMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHM 407
Query: 361 TVLSIRTSEFVNAVSKLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV--- 413
L + VN V+ LH+ V +++ + LWP +TNG+ W+
Sbjct: 408 ANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQC 461
Query: 414 NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRN 473
N LA L D + K W ++ +E+ D + + ++ ++ + +K
Sbjct: 462 NPALAALLDKSLQKEWANDLDQ---LINLEKFADDAKFRQQYREIKQANKVRLAEFVK-- 516
Query: 474 ERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIF 529
R GI+ I+ A+ +R YKR L L L K I NP+ P +F
Sbjct: 517 VRTGIE-----INPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVPRVFLF 571
Query: 530 GGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLN 583
G KA P K + + +V+ + K K++ + +Y + +A L+ D+
Sbjct: 572 GAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQ 631
Query: 584 TPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
EASGT MK LNG + + DG VE
Sbjct: 632 ISTAGKEASGTGNMKLALNGALTVGTLDGANVE 664
>gi|6755256 muscle glycogen phosphorylase [Mus musculus]
>gi|4836513|gb|AAD30476.1|AF124787_1 (AF124787) muscle
glycogen phosphorylase [Mus musculus]
Length = 842
Score = 78.8 bits (191), Expect = 2e-13
Identities = 90/375 (24%), Positives = 162/375 (43%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A ++ T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELMRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMET 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 396 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L ++ +I ++
Sbjct: 456 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEVIAERIGEDY 512
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 513 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFSAYLER----EYKVHINPNSLF 564
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+KR N P I+ GGKA P K ++ +
Sbjct: 565 DVQVKRIHEYKRQLLNCLHIITLYNRIKREPNRFMVPRTIMIGGKAAPGYHMAKMIIKLI 624
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 625 TAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 684
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 685 NGALTIGTMDGANVE 699
>pdb|1E4O|A Chain A, Phosphorylase Recognition And Phosphorolysis Of Its
Oligosaccharide Substrate: Answers To A Long Outstanding
Question >gi|10120894|pdb|1E4O|B Chain B, Phosphorylase
Recognition And Phosphorolysis Of Its Oligosaccharide
Substrate: Answers To A Long Outstanding Question
>gi|7246003|pdb|1QM5|A Chain A, Phosphorylase
Recognition And Phosphorylysis Of Its Oligosaccharide
Substrate: Answers To A Long Outstanding Question
>gi|7246004|pdb|1QM5|B Chain B, Phosphorylase
Recognition And Phosphorylysis Of Its Oligosaccharide
Substrate: Answers To A Long Outstanding Question
Length = 796
Score = 78.8 bits (191), Expect = 2e-13
Identities = 95/393 (24%), Positives = 162/393 (41%), Gaps = 51/393 (12%)
Query: 257 IGGMRLLKALEIEPGVIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHT 315
+ G +L + + E VI LN+ HP+ A E +R + E +++++A + T +T HT
Sbjct: 289 LAGRKLHELADYE--VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHT 346
Query: 316 PVPAGHDVFPVDFVREKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNM 360
+P + + V V+ L L + P D+ + D +M
Sbjct: 347 LMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHM 406
Query: 361 TVLSIRTSEFVNAVSKLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV--- 413
L + VN V+ LH+ V +++ + LWP +TNG+ W+
Sbjct: 407 ANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQC 460
Query: 414 NENLAKLYDIYIGKIWREHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRN 473
N LA L D + K W ++ +E+ D + + ++ ++ + +K
Sbjct: 461 NPALAALLDKSLQKEWANDLDQ---LINLEKFADDAKFRDQYREIKQANKVRLAEFVK-- 515
Query: 474 ERLGIDEPLPDIDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIF 529
R GI+ I+ A+ +R YKR L L L K I NP+ P +F
Sbjct: 516 VRTGIE-----INPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVPRVFLF 570
Query: 530 GGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLN 583
G KA P K + + +V+ + K K++ + +Y + +A L+ D+
Sbjct: 571 GAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQ 630
Query: 584 TPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
EASGT MK LNG + + DG VE
Sbjct: 631 ISTAGKEASGTGNMKLALNGALTVGTLDGANVE 663
>pir||S00596 maltodextrin phosphorylase (EC 2.4.1.1) - Escherichia coli
>gi|225544|prf||1305411A phosphorylase,maltodextrin
[Escherichia coli]
Length = 797
Score = 78.4 bits (190), Expect = 3e-13
Identities = 94/382 (24%), Positives = 157/382 (40%), Gaps = 57/382 (14%)
Query: 272 VIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVR 330
VI LN+ HP+ A E +R + E +++++A + T +T HT +P + + V V+
Sbjct: 303 VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVK 362
Query: 331 EKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVS 375
L L + P D+ + D +M L + VN V+
Sbjct: 363 GLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHMANLCVVGGFAVNGVA 422
Query: 376 KLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKI 428
LH+ V +++ + LWP +TNG+ W+ N LA L D + K
Sbjct: 423 ALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQCNPALAALLDKSLQKE 476
Query: 429 WREHVNLEGIWYAIERIPDSELWEAHLKAKR----EVIELIRRKIMKRNERLGIDEPLPD 484
W +L+ + ++ D++ + + K+ + E ++ R GID
Sbjct: 477 WAN--DLDQLINLVKLADDAKFRDLYRVIKQANKVRLAEFVK-------VRTGID----- 522
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
I+ A+ +R YKR L L L K I NP+ P +FG KA P
Sbjct: 523 INPQAIFDIQIKRLHEYKRQHLNLLRILALYKEIRENPQADRVPRVFLFGAKAAPGYYLA 582
Query: 541 KEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+ + K K++ + +Y + +A L+ D+ EASGT
Sbjct: 583 KNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASGT 642
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG VE
Sbjct: 643 GNMKLALNGALTVGTLDGANVE 664
>pdb|1NOJ| Complex Of Glycogen Phosphorylase With A Transition State Analogue
Nojirimycin Tetrazole And Phosphate In The T State
>gi|1633146|pdb|1NOK| Complex Of Glycogen Phosphorylase
With A Transition State Analogue Nojirimycin Tetrazole
And Phosphate In The T State >gi|1827888|pdb|1NOI|A
Chain A, Complex Of Glycogen Phosphorylase With A
Transition State Analogue Nojirimycin Tetrazole And
Phosphate In The T And R States >gi|1827889|pdb|1NOI|B
Chain B, Complex Of Glycogen Phosphorylase With A
Transition State Analogue Nojirimycin Tetrazole And
Phosphate In The T And R States >gi|1827890|pdb|1NOI|C
Chain C, Complex Of Glycogen Phosphorylase With A
Transition State Analogue Nojirimycin Tetrazole And
Phosphate In The T And R States >gi|1827891|pdb|1NOI|D
Chain D, Complex Of Glycogen Phosphorylase With A
Transition State Analogue Nojirimycin Tetrazole And
Phosphate In The T And R States
Length = 842
Score = 78.4 bits (190), Expect = 3e-13
Identities = 90/375 (24%), Positives = 161/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 335 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLET 394
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 395 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 454
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 455 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 511
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 512 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 563
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGK P K ++ +
Sbjct: 564 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKPAPGYHMAKMIIKLI 623
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 624 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 683
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 684 NGALTIGTMDGANVE 698
>pdb|1AHP|A Chain A, Oligosaccharide Substrate Binding In Escherichia Coli
Maltodextrin Phsphorylase >gi|2624862|pdb|1AHP|B Chain
B, Oligosaccharide Substrate Binding In Escherichia Coli
Maltodextrin Phsphorylase
Length = 797
Score = 78.4 bits (190), Expect = 3e-13
Identities = 94/382 (24%), Positives = 157/382 (40%), Gaps = 57/382 (14%)
Query: 272 VIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVR 330
VI LN+ HP+ A E +R + E +++++A + T +T HT +P + + V V+
Sbjct: 303 VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVK 362
Query: 331 EKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVS 375
L L + P D+ + D +M L + VN V+
Sbjct: 363 GLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHMANLCVVGGFAVNGVA 422
Query: 376 KLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKI 428
LH+ V +++ + LWP +TNG+ W+ N LA L D + K
Sbjct: 423 ALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQCNPALAALLDKSLQKE 476
Query: 429 WREHVNLEGIWYAIERIPDSELWEAHLKAKR----EVIELIRRKIMKRNERLGIDEPLPD 484
W +L+ + ++ D++ + + K+ + E ++ R GID
Sbjct: 477 WAN--DLDQLINLVKLADDAKFRDLYRVIKQANKVRLAEFVK-------VRTGID----- 522
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
I+ A+ +R YKR L L L K I NP+ P +FG KA P
Sbjct: 523 INPQAIFDIQIKRLHEYKRQHLNLLRILALYKEIRENPQADRVPRVFLFGAKAAPGYYLA 582
Query: 541 KEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+ + K K++ + +Y + +A L+ D+ EASGT
Sbjct: 583 KNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASGT 642
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG VE
Sbjct: 643 GNMKLALNGALTVGTLDGANVE 664
>pdb|2ECP|A Chain A, The Crystal Structure Of The E. Coli Maltodextrin
Phosphorylase Complex >gi|5542507|pdb|2ECP|B Chain B,
The Crystal Structure Of The E. Coli Maltodextrin
Phosphorylase Complex
Length = 796
Score = 78.4 bits (190), Expect = 3e-13
Identities = 94/382 (24%), Positives = 157/382 (40%), Gaps = 57/382 (14%)
Query: 272 VIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVR 330
VI LN+ HP+ A E +R + E +++++A + T +T HT +P + + V V+
Sbjct: 302 VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVK 361
Query: 331 EKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVS 375
L L + P D+ + D +M L + VN V+
Sbjct: 362 GLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHMANLCVVGGFAVNGVA 421
Query: 376 KLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKI 428
LH+ V +++ + LWP +TNG+ W+ N LA L D + K
Sbjct: 422 ALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQCNPALAALLDKSLQKE 475
Query: 429 WREHVNLEGIWYAIERIPDSELWEAHLKAKR----EVIELIRRKIMKRNERLGIDEPLPD 484
W +L+ + ++ D++ + + K+ + E ++ R GID
Sbjct: 476 WAN--DLDQLINLVKLADDAKFRDLYRVIKQANKVRLAEFVK-------VRTGID----- 521
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
I+ A+ +R YKR L L L K I NP+ P +FG KA P
Sbjct: 522 INPQAIFDIQIKRLHEYKRQHLNLLRILALYKEIRENPQADRVPRVFLFGAKAAPGYYLA 581
Query: 541 KEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+ + K K++ + +Y + +A L+ D+ EASGT
Sbjct: 582 KNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASGT 641
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG VE
Sbjct: 642 GNMKLALNGALTVGTLDGANVE 663
>emb|CAA29949.1| (X06791) maltodextrin phosphorylase [Escherichia coli]
Length = 797
Score = 78.0 bits (189), Expect = 4e-13
Identities = 94/382 (24%), Positives = 157/382 (40%), Gaps = 57/382 (14%)
Query: 272 VIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVR 330
VI LN+ HP+ A E +R + E +++++A + T +T HT +P + + V V+
Sbjct: 303 VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVK 362
Query: 331 EKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVS 375
L L + P D+ + D +M L + VN V+
Sbjct: 363 GLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHMANLCVVGGFAVNGVA 422
Query: 376 KLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKI 428
LH+ V +++ + LWP +TNG+ W+ N LA L D + K
Sbjct: 423 ALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQCNPALAALLDKSLQKE 476
Query: 429 WREHVNLEGIWYAIERIPDSELWEAHLKAKR----EVIELIRRKIMKRNERLGIDEPLPD 484
W +L+ + ++ D++ + + K+ + E ++ R GID
Sbjct: 477 WAN--DLDQLINLVKLADDAKFRDLYRVIKQANKVRLAEFVK-------VRTGID----- 522
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
I+ A+ +R YKR L L L K I NP+ P +FG KA P
Sbjct: 523 INPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVPRVFLFGAKAAPGYYLA 582
Query: 541 KEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+ + K K++ + +Y + +A L+ D+ EASGT
Sbjct: 583 KNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASGT 642
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG VE
Sbjct: 643 GNMKLALNGALTVGTLDGANVE 664
>sp|P00490|PHSM_ECOLI MALTODEXTRIN PHOSPHORYLASE
Length = 797
Score = 78.0 bits (189), Expect = 4e-13
Identities = 94/382 (24%), Positives = 157/382 (40%), Gaps = 57/382 (14%)
Query: 272 VIHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVR 330
VI LN+ HP+ A E +R + E +++++A + T +T HT +P + + V V+
Sbjct: 303 VIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVK 362
Query: 331 EKL---------------RLFLRDLPQDKFLGLGKVTPEDTNFNMTVLSIRTSEFVNAVS 375
L L + P D+ + D +M L + VN V+
Sbjct: 363 GLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQVHMANLCVVGGFAVNGVA 422
Query: 376 KLHAK-VTREM---WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKI 428
LH+ V +++ + LWP +TNG+ W+ N LA L D + K
Sbjct: 423 ALHSDLVVKDLFPEYHQLWPN------KFHNVTNGITPRRWIKQCNPALAALLDKSLQKE 476
Query: 429 WREHVNLEGIWYAIERIPDSELWEAHLKAKR----EVIELIRRKIMKRNERLGIDEPLPD 484
W +L+ + ++ D++ + + K+ + E ++ R GID
Sbjct: 477 WAN--DLDQLINLVKLADDAKFRQLYRVIKQANKVRLAEFVK-------VRTGID----- 522
Query: 485 IDENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAG 540
I+ A+ +R YKR L L L K I NP+ P +FG KA P
Sbjct: 523 INPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVPRVFLFGAKAAPGYYLA 582
Query: 541 KEFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGT 594
K + + +V+ + K K++ + +Y + +A L+ D+ EASGT
Sbjct: 583 KNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASGT 642
Query: 595 SGMKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG VE
Sbjct: 643 GNMKLALNGALTVGTLDGANVE 664
>pdb|1A8I| Spirohydantoin Inhibitor Of Glycogen Phosphorylase
>gi|3318706|pdb|2GPN| 100 K Structure Of Glycogen
Phosphorylase At 2.0 Angstroms Resolution
Length = 842
Score = 78.0 bits (189), Expect = 4e-13
Identities = 90/375 (24%), Positives = 161/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 335 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLET 394
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 395 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 454
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 455 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 511
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 512 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 563
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGKA P K ++ +
Sbjct: 564 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLI 623
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT M L
Sbjct: 624 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMXFML 683
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 684 NGALTIGTMDGANVE 698
>emb|CAA27816.1| (X04265) glycogen phosphorylase (aa 1-843) [Oryctolagus cuniculus]
>gi|217748|dbj|BAA00027.1| (D00040) glycogen
phosphorylase [Oryctolagus cuniculus]
Length = 843
Score = 77.6 bits (188), Expect = 5e-13
Identities = 90/375 (24%), Positives = 161/375 (42%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + L +++A E+ T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLET 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 396 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L +I +I E+
Sbjct: 456 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEIIAERIGEEY 512
Query: 433 VN-LEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
++ L+ + + + D EA ++ +V + + K ER E I+ N+L
Sbjct: 513 ISDLDQLRKLLSYVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNSLF 564
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+K+ N P ++ GGK P K ++ +
Sbjct: 565 DVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKPAPGYHMAKMIIKLI 624
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + ++I +ENY + A ++ D+ EASGT MK L
Sbjct: 625 TAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFML 684
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 685 NGALTIGTMDGANVE 699
>pir||A83379 glycogen phosphorylase PA2144 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948161|gb|AAG05532.1|AE004641_11
(AE004641) glycogen phosphorylase [Pseudomonas
aeruginosa]
Length = 812
Score = 77.3 bits (187), Expect = 7e-13
Identities = 95/380 (25%), Positives = 160/380 (42%), Gaps = 43/380 (11%)
Query: 269 EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVD 327
E I LN+ HP+ A E +R ++ L + +A L AT +T HT +P + +PV
Sbjct: 314 EQVAIQLNDTHPAIAVAELMRQLVDVHQLAWPDAWALSVATLSYTNHTLLPEALESWPVA 373
Query: 328 FVREKLRLFLRDLPQDKFLGLGKVTPEDTN------------------FNMTVLSIRTSE 369
+ L ++ + + + +D + M L+ S
Sbjct: 374 LMERLLPRHMQIIYLINAFHIDALRAQDIHDFDLLRSVSLIEEGHGRRVRMGNLAFLGSH 433
Query: 370 FVNAVSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKI 428
+N VS LH ++ RE ++ +L P I TNGV W+ + L ++ + +
Sbjct: 434 QINGVSALHTELMRETVFHDLHRLYPQR---ISNKTNGVSFRRWLFQANPGLTELLVETL 490
Query: 429 WREHVNLEGIWYAIERIPDSE--LWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDID 486
+ ++ R+PD E + +A L+A+ RR+ RL +D I+
Sbjct: 491 GADLLDTPE-----RRLPDLEEHVEDARLRAR---FAEQRRQNKTALARLVLDSLGVAIE 542
Query: 487 ENALIIGFARRFATYKRAIL-LFTDLERLKRIVNNPER---PVYIIFGGKAHPMDEAGKE 542
AL +R YKR +L L + + I N+P P IF GKA K
Sbjct: 543 PEALFDVHIKRIHEYKRQLLNLLHTVALYQEIRNDPTADRVPRVKIFAGKAAASYHQAKL 602
Query: 543 FLRRVYEVSQM----PEFKG--KIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSG 596
++ ++++ P +G K++ + NY++ A ++ D+ LEASGTS
Sbjct: 603 IIKLANDIARTINDDPTVRGLLKLVFLPNYNVSLAEAIIPAADLSEQISTAGLEASGTSN 662
Query: 597 MKAGLNGVINLSVFDGWWVE 616
MK LNG + + DG VE
Sbjct: 663 MKFALNGALTIGTLDGANVE 682
>pir||A27335 glycogen phosphorylase (EC 2.4.1.1), muscle - human
>gi|190784|gb|AAA60231.1| (M32598) glycogen
phosphorylase [Homo sapiens]
Length = 842
Score = 77.3 bits (187), Expect = 7e-13
Identities = 93/377 (24%), Positives = 163/377 (42%), Gaps = 46/377 (12%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + + +++A ++ T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELMRILVDLERMDWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLET 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 396 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIW 429
V+++H+++ ++ ++ + + P TNG+ W+ N LA++ IG+ +
Sbjct: 456 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEVIAERIGEDF 512
Query: 430 REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENA 489
+L+ + + + D EA ++ +V + + K ER E I+ N+
Sbjct: 513 IS--DLDQLRKLLSFVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNS 562
Query: 490 LIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
L +R YKR +L + T R+KR N P ++ GGKA P K +R
Sbjct: 563 LFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFVPRTVMIGGKAAPGYHMAKMIIR 622
Query: 546 RVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKA 599
V + + + ++I +ENY + A ++ D+ EASGT MK
Sbjct: 623 LVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKF 682
Query: 600 GLNGVINLSVFDGWWVE 616
LNG + + DG VE
Sbjct: 683 MLNGALTIGTMDGANVE 699
>gi|5032009 phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage
disease type V); Phosphorylase, glycogen, muscle [Homo
sapiens] >gi|11441366|ref|XP_006535.1| phosphorylase,
glycogen; muscle (McArdle syndrome, glycogen storage
disease type V) [Homo sapiens]
>gi|3041717|sp|P11217|PHS2_HUMAN GLYCOGEN PHOSPHORYLASE,
MUSCLE FORM (MYOPHOSPHORYLASE)
>gi|2232007|gb|AAC52081.1| (U94777) muscle glycogen
phosphorylase [Homo sapiens] >gi|3153910|gb|AAC17451.1|
(AF066859) muscle glycogen phosphorylase [Homo sapiens]
Length = 842
Score = 77.3 bits (187), Expect = 7e-13
Identities = 93/377 (24%), Positives = 163/377 (42%), Gaps = 46/377 (12%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HPS A E +R ++ + + +++A ++ T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPSLAIPELMRILVDLERMDWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLET 395
Query: 332 KLRLFLRDLPQDKFLGLGKVT---PEDTN---------------FNMTVLSIRTSEFVNA 373
L L+ + + L +V P D + NM L I S VN
Sbjct: 396 LLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIW 429
V+++H+++ ++ ++ + + P TNG+ W+ N LA++ IG+ +
Sbjct: 456 VARIHSEILKKTIFKDFYELEPHK---FQNKTNGITPRRWLVLCNPGLAEVIAERIGEDF 512
Query: 430 REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENA 489
+L+ + + + D EA ++ +V + + K ER E I+ N+
Sbjct: 513 IS--DLDQLRKLLSFVDD----EAFIRDVAKVKQENKLKFAAYLER----EYKVHINPNS 562
Query: 490 LIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
L +R YKR +L + T R+KR N P ++ GGKA P K +R
Sbjct: 563 LFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFVPRTVMIGGKAAPGYHMAKMIIR 622
Query: 546 RVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKA 599
V + + + ++I +ENY + A ++ D+ EASGT MK
Sbjct: 623 LVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKF 682
Query: 600 GLNGVINLSVFDGWWVE 616
LNG + + DG VE
Sbjct: 683 MLNGALTIGTMDGANVE 699
>pir||A29949 glycogen phosphorylase (EC 2.4.1.1), brain (astrocytoma cell line)
- human >gi|307200|gb|AAA59597.1| (J03544) brain
glycogen phosphorylase [Homo sapiens]
Length = 863
Score = 76.1 bits (184), Expect = 2e-12
Identities = 129/583 (22%), Positives = 232/583 (39%), Gaps = 109/583 (18%)
Query: 126 SGGLGILAGDHLKTASDLGLPLIAIGLLYKHGYFKQEIDRDGRQIEKF------------ 173
+GGLG LA L + + LGL G+ Y+ G F Q+I +G Q+E+
Sbjct: 134 NGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIV-NGWQVEEADDWLRYGNPWEK 192
Query: 174 --PEYNIREMPIRQVLNNDGTP-------------LLIDVPIED---------RIVKARV 209
PEY + P+ + TP + D P+ R+ AR
Sbjct: 193 ARPEYML---PVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSARA 249
Query: 210 ---FLVEVGRVKLYL---LDTDVPENREDDRRICDYLYNAEPDKRIKQEILIGIGG---- 259
F ++ V Y+ LD ++ EN D + + + R+KQE + +G
Sbjct: 250 PNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGK-ELRLKQEYFV-VGATLQD 307
Query: 260 -MRLLKALEI--------------EPGVIHLNEGHPSFANFERIRWFME-KGLTFEEALE 303
+R K+ + + I LN+ HP+ + E +R ++ + + +++A E
Sbjct: 308 IIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWE 367
Query: 304 LVRATSVFTTHTPVPAGHDVFPVDFVREKLRLFLR---DLPQDKFLGLGKVTPEDTN--- 357
+ + T +T HT +P + +PV + L L + Q + + P D +
Sbjct: 368 ITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLR 427
Query: 358 ------------FNMTVLSIRTSEFVNAVSKLHAKVTRE-MWSNLWPGVPTDEIPIDAIT 404
NM L + S VN V+++H+++ ++ ++ + + P T
Sbjct: 428 RMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEK---FQNKT 484
Query: 405 NGVHTPTWVNENLAKLYDIYIGKIWREHV-NLEGIWYAIERIPDSELWEAHLKAKREVIE 463
NG+ W+ L D + KI E + +L + + + D K K+E +
Sbjct: 485 NGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQEN-K 543
Query: 464 LIRRKIMKRNERLGIDEPLPDIDENALIIGFARRFATYKRAIL----LFTDLERLKRIVN 519
L +++ ++ I+ +++ +R YKR +L + T R+KR
Sbjct: 544 LKFSAFLEKEYKV-------KINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPA 596
Query: 520 NPERPVYIIFGGKAHPMDEAGKEFLRRVYEVSQMPEF------KGKIILIENYDMGSARI 573
P ++ GGKA P K ++ V + + + K+I +ENY + A
Sbjct: 597 KAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEK 656
Query: 574 LVSGVDVWLNTPRRPLEASGTSGMKAGLNGVINLSVFDGWWVE 616
++ D+ EASGT MK LNG + + DG VE
Sbjct: 657 VIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVE 699
>sp|P73511|PHSG_SYNY3 GLYCOGEN PHOSPHORYLASE >gi|7433823|pir||S77217 phosphorylase (EC
2.4.1.1) 1 - Synechocystis sp. (strain PCC 6803)
>gi|1652631|dbj|BAA17551.1| (D90907) glycogen
phosphorylase [Synechocystis sp.]
Length = 849
Score = 73.4 bits (177), Expect = 1e-11
Identities = 102/409 (24%), Positives = 170/409 (40%), Gaps = 58/409 (14%)
Query: 273 IHLNEGHPSFANFERIRWFM-EKGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
+ +N+ HPS A E +R + E ++ A + AT FT HT +P + + + E
Sbjct: 334 VQMNDTHPSIAVAELMRLLVDEHHYEWQRAWAITEATFGFTNHTLLPEALEKWSLPLFGE 393
Query: 332 KLRLFLRDLPQ--DKFLGLGKVT-PED---------------TNFNMTVLSIRTSEFVNA 373
L L + + +FL ++ P D + M L+ S +N
Sbjct: 394 MLPRHLEIIYEINQRFLDQVRMKYPNDGDRLARLSIIDEAGEKSVRMAYLATVGSHAING 453
Query: 374 VSKLHAKVTREM----WSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIG 426
V+ LH+++ +E + LWP +++ TNGV W+ N L+ L IG
Sbjct: 454 VAALHSQLVKETILKDFYELWPEKFSNK------TNGVTPRRWMVLSNPRLSNLISSRIG 507
Query: 427 KIWREHVNLEGIWYAIERIPD-SELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDI 485
W + NL+ + +E D + + K KREV + + R I R + + + L D+
Sbjct: 508 DGWIK--NLDEL-KQLEPFADLAGFRQDWCKVKREVKQDLARYIHTRTDLVVNPDSLFDV 564
Query: 486 DENALIIGFARRFATYKRAILLFTDLERLK-RIVNNPE---RPVYIIFGGKAHPMDEAGK 541
+R YKR L + L +I NNP P I+GGKA P K
Sbjct: 565 Q--------VKRIHEYKRQHLNILHVIHLYLQIKNNPNLDVTPRTFIYGGKAAPGYFTAK 616
Query: 542 EFLRRVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTS 595
++ + V+ + + K+I + +Y++ + + D+ EASGT
Sbjct: 617 LIIKLINSVADVVNNDPTIGDRLKVIFLPDYNVKFGQRVYPAADLSEQISTAGKEASGTG 676
Query: 596 GMKAGLNGVINLSVFDGWWV---EGYNGRNGWVIGDATLEPE-TEADDY 640
MK +NG + + DG + E N ++ G T E E T A+ Y
Sbjct: 677 NMKFSMNGALTIGTLDGANIEIREEVGAENFFLFGLTTPEVEKTLAEGY 725
>gi|4506351 phosphorylase, glycogen; brain [Homo sapiens]
>gi|1730558|sp|P11216|PHS3_HUMAN GLYCOGEN PHOSPHORYLASE,
BRAIN FORM >gi|106138|pir||A40138 glycogen phosphorylase
(EC 2.4.1.1), brain - human >gi|1172226|gb|AAB60395.1|
(U47025) glycogen phosphorylase B [Homo sapiens]
>gi|227307|prf||1701409A glycogen phosphorylase [Homo
sapiens]
Length = 843
Score = 72.2 bits (174), Expect = 2e-11
Identities = 84/375 (22%), Positives = 157/375 (41%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ + E +R ++ + + +++A E+ + T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEK 395
Query: 332 KLRLFLR---DLPQDKFLGLGKVTPEDTN---------------FNMTVLSIRTSEFVNA 373
L L + Q + + P D + NM L + S VN
Sbjct: 396 LLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L D + KI E
Sbjct: 456 VARIHSEIVKQSVFKDFYELEPEK---FQNKTNGITPRRWLLLCNPGLADTIVEKIGEEF 512
Query: 433 V-NLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
+ +L + + + D K K+E +L +++ ++ I+ +++
Sbjct: 513 LTDLSQLKKLLPLVSDEVFIRDVAKVKQEN-KLKFSAFLEKEYKV-------KINPSSMF 564
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+KR P ++ GGKA P K ++ V
Sbjct: 565 DVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLV 624
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + K+I +ENY + A ++ D+ EASGT MK L
Sbjct: 625 TSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFML 684
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 685 NGALTIGTMDGANVE 699
>gi|11420375 phosphorylase, glycogen; brain [Homo sapiens]
>gi|9650807|emb|CAC00661.1| (AL121772) dJ965G21.1
(Glycogen Phosphorylase, brain form (EC 2.4.1.1)) [Homo
sapiens]
Length = 843
Score = 72.2 bits (174), Expect = 2e-11
Identities = 84/375 (22%), Positives = 157/375 (41%), Gaps = 42/375 (11%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ + E +R ++ + + +++A E+ + T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEK 395
Query: 332 KLRLFLR---DLPQDKFLGLGKVTPEDTN---------------FNMTVLSIRTSEFVNA 373
L L + Q + + P D + NM L + S VN
Sbjct: 396 LLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWVNENLAKLYDIYIGKIWREH 432
V+++H+++ ++ ++ + + P TNG+ W+ L D + KI E
Sbjct: 456 VARIHSEIVKQSVFKDFYELEPEK---FQNKTNGITPRRWLLLCNPGLADTIVEKIGEEF 512
Query: 433 V-NLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENALI 491
+ +L + + + D K K+E +L +++ ++ I+ +++
Sbjct: 513 LTDLSQLKKLLPLVSDEVFIRDVAKVKQEN-KLKFSAFLEKEYKV-------KINPSSMF 564
Query: 492 IGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLRRV 547
+R YKR +L + T R+KR P ++ GGKA P K ++ V
Sbjct: 565 DVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLV 624
Query: 548 YEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKAGL 601
+ + + K+I +ENY + A ++ D+ EASGT MK L
Sbjct: 625 TSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFML 684
Query: 602 NGVINLSVFDGWWVE 616
NG + + DG VE
Sbjct: 685 NGALTIGTMDGANVE 699
>sp|P53534|PHS3_RAT GLYCOGEN PHOSPHORYLASE, BRAIN FORM >gi|204421|gb|AAA41252.1|
(L10668) glycogen phosphorylase [Rattus norvegicus]
Length = 838
Score = 70.6 bits (170), Expect = 7e-11
Identities = 84/377 (22%), Positives = 160/377 (42%), Gaps = 46/377 (12%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ + E +R ++ + + +++A E+ + T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEK 395
Query: 332 KLRLFLR---DLPQDKFLGLGKVTPEDTN---------------FNMTVLSIRTSEFVNA 373
L L + Q + + P D + NM L + S VN
Sbjct: 396 LLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIW 429
V+++H+++ ++ ++ + + P TNG+ W+ N LA++ IG+ +
Sbjct: 456 VARIHSEIVKQSVFKDFYELEPEK---FQNKTNGITPRRWLLLCNPGLAEIIVERIGEGF 512
Query: 430 REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENA 489
+L + + + D EA ++ +V + + K + E+ E I+ +
Sbjct: 513 L--TDLSQLKKLLSLVDD----EAFIRDVAKVKQENKLKFSAQLEK----EYKVKINPCS 562
Query: 490 LIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
+ +R YKR +L + T R+K+ P ++ GGKA P K ++
Sbjct: 563 MFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIK 622
Query: 546 RVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKA 599
V + + + ++I +ENY + A ++ D+ EASGT MK
Sbjct: 623 LVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKF 682
Query: 600 GLNGVINLSVFDGWWVE 616
LNG + + DG VE
Sbjct: 683 MLNGALTIGTMDGANVE 699
>pir||S37300 glycogen phosphorylase (EC 2.4.1.1), brain - rat
Length = 843
Score = 70.6 bits (170), Expect = 7e-11
Identities = 84/377 (22%), Positives = 160/377 (42%), Gaps = 46/377 (12%)
Query: 273 IHLNEGHPSFANFERIRWFME-KGLTFEEALELVRATSVFTTHTPVPAGHDVFPVDFVRE 331
I LN+ HP+ + E +R ++ + + +++A E+ + T +T HT +P + +PV +
Sbjct: 336 IQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEK 395
Query: 332 KLRLFLR---DLPQDKFLGLGKVTPEDTN---------------FNMTVLSIRTSEFVNA 373
L L + Q + + P D + NM L + S VN
Sbjct: 396 LLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNG 455
Query: 374 VSKLHAKVTRE-MWSNLWPGVPTDEIPIDAITNGVHTPTWV---NENLAKLYDIYIGKIW 429
V+++H+++ ++ ++ + + P TNG+ W+ N LA++ IG+ +
Sbjct: 456 VARIHSEIVKQSVFKDFYELEPEK---FQNKTNGITPRRWLLLCNPGLAEIIVERIGEGF 512
Query: 430 REHVNLEGIWYAIERIPDSELWEAHLKAKREVIELIRRKIMKRNERLGIDEPLPDIDENA 489
+L + + + D EA ++ +V + + K + E+ E I+ +
Sbjct: 513 L--TDLSQLKKLLSLVDD----EAFIRDVAKVKQENKLKFSAQLEK----EYKVKINPCS 562
Query: 490 LIIGFARRFATYKRAIL----LFTDLERLKRIVNNPERPVYIIFGGKAHPMDEAGKEFLR 545
+ +R YKR +L + T R+K+ P ++ GGKA P K ++
Sbjct: 563 MFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIK 622
Query: 546 RVYEVSQMPEF------KGKIILIENYDMGSARILVSGVDVWLNTPRRPLEASGTSGMKA 599
V + + + ++I +ENY + A ++ D+ EASGT MK
Sbjct: 623 LVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKF 682
Query: 600 GLNGVINLSVFDGWWVE 616
LNG + + DG VE
Sbjct: 683 MLNGALTIGTMDGANVE 699
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.140 0.429
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 333467390
Number of Sequences: 2977
Number of extensions: 15220593
Number of successful extensions: 40171
Number of sequences better than 1.0e-10: 76
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 39839
Number of HSP's gapped (non-prelim): 193
length of query: 835
length of database: 189,106,746
effective HSP length: 54
effective length of query: 781
effective length of database: 156,788,448
effective search space: 122451777888
effective search space used: 122451777888
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 169 (70.2 bits)