BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB2426 (pheS) DE:phenylalanyl-tRNA synthetase, subunit alpha
(pheS)
(500 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75049 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain... 996 0.0
pir||C71111 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain... 847 0.0
pir||C69199 phenylalanine--tRNA ligase (EC 6.1.1.20) - Methanoba... 330 3e-89
gi|11499537 phenylalanyl-tRNA synthetase, subunit alpha (pheS) [... 320 3e-86
sp|Q57911|SYF_METJA PROBABLE PHENYLALANYL-TRNA SYNTHETASE (PHENY... 316 4e-85
gb|AAK40456.1| Phenylalanyl-tRNA synthetase alpha subunit (pheS)... 291 2e-77
sp|P95961|SYF_SULSO PROBABLE PHENYLALANYL-TRNA SYNTHETASE (PHENY... 291 2e-77
sp|O83938|SYFA_TREPA PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 279 7e-74
sp|P94282|SYFA_BORBU PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 268 1e-70
pir||B72457 probable phenylalanyl-tRNA synthetase alpha chain AP... 259 7e-68
gb|AAG20567.1| (AE005127) phenylalanyl-tRNA synthetase subunit a... 256 4e-67
dbj|BAA95666.1| (D84471) phenylalanyl tRNA synthetase beta subun... 246 5e-64
gi|4758340 phenylalanine-tRNA synthetase-like protein [Homo sapi... 245 6e-64
emb|CAC11777.1| (AL445064) phenylalanine--tRNA ligase beta chain... 244 1e-63
pir||T45074 probable phenylalanine--tRNA ligase (EC 6.1.1.20) [i... 242 6e-63
pir||T28752 phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain ... 238 1e-61
gb|AAF46332.1| (AE003443) CG2263 gene product [Drosophila melano... 231 2e-59
gb|AAA35152.1| (J03965) Phe-RNA synthetase [Saccharomyces cerevi... 221 1e-56
gi|6321087 Phenylalanyl-tRNA synthetase, beta subunit, cytoplasm... 221 2e-56
pir||T11642 phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain ... 217 2e-55
pir||T08576 phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain ... 195 9e-49
gb|AAB41018.1| (U82978) phenylalanyl-tRNA synthetase alpha subun... 142 1e-32
sp|P27001|SYFA_THETH PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 120 5e-26
dbj|BAB06830.1| (AP001517) phenylalanyl-tRNA synthetase alpha su... 114 3e-24
pir||C82225 phenylalanyl-tRNA synthetase, alpha chain VC1219 [im... 111 1e-23
pir||D70620 probable pheS protein - Mycobacterium tuberculosis (... 111 2e-23
pir||H72329 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain... 111 2e-23
sp|P17921|SYFA_BACSU PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 108 2e-22
sp|Q55187|SYFA_SYNY3 PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 105 1e-21
pir||T36830 probable phenylalanyl-tRNA synthetase alpha chain - ... 105 1e-21
emb|CAA37224.1| (X53057) phenylalanyl-tRNA synthetase alpha subu... 103 5e-21
sp|O67087|SYFA_AQUAE PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 102 1e-20
sp|P57229|SYFA_BUCAI PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 101 2e-20
sp|Q9ZDB5|SYFA_RICPR PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 100 4e-20
emb|CAA23564.1| (V00291) phenylalanyl-tRNA synthetase beta-subun... 100 5e-20
gb|AAA51469.1| (K02844) phenylalanyl-tRNA synthetase alpha-subun... 100 5e-20
sp|P08312|SYFA_ECOLI PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 100 6e-20
dbj|BAA15482.1| (D90813) Phenylalanine--tRNA ligase (EC 6.1.1.20... 100 6e-20
sp|Q9ZKF9|SYFA_HELPJ PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 99 1e-19
gb|AAB61946.1| (U01668) phenylalanyl-tRNA synthetase alpha subun... 98 2e-19
sp|P56146|SYFA_HELPY PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 98 2e-19
sp|P43819|SYFA_HAEIN PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 96 7e-19
pir||F81939 probable phenylalanine--tRNA ligase (EC 6.1.1.20) al... 96 7e-19
pir||H75283 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain... 96 9e-19
pir||G81165 phenylalanyl-tRNA synthetase, alpha chain NMB0724 [i... 96 9e-19
pir||B82767 phenylalanyl-tRNA synthetase alpha chain XF0741 [imp... 92 1e-17
pir||A81363 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain... 92 2e-17
pir||C82888 phenylalanine-tRNA synthetase alpha chain UU458 [imp... 87 4e-16
pir||D71465 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain... 84 3e-15
pir||B83303 phenylalanyl-tRNA synthetase, alpha-subunit PA2740 [... 82 1e-14
pir||B72011 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain... 81 3e-14
pir||T45974 phenylalanine-tRNA synthetase-like protein - Arabido... 80 8e-14
pir||F81727 phenylalanyl-tRNA synthetase, alpha chain TC0224 [im... 79 1e-13
pir||B64507 hypothetical protein MJ1660 - Methanococcus jannasch... 77 5e-13
sp|P47436|SYFA_MYCGE PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (P... 75 1e-12
>pir||D75049 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain PAB2426 -
Pyrococcus abyssi (strain Orsay)
>gi|5458802|emb|CAB50289.1| (AJ248287) phenylalanyl-tRNA
synthetase, subunit alpha (pheS) [Pyrococcus abyssi]
Length = 500
Score = 996 bits (2546), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 1 MTLGYNEKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIV 60
MTLGYNEKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIV
Sbjct: 1 MTLGYNEKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIV 60
Query: 61 LTDIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKD 120
LTDIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKD
Sbjct: 61 LTDIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKD 120
Query: 121 EKGLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVE 180
EKGLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVE
Sbjct: 121 EKGLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVE 180
Query: 181 RTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQP 240
RTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQP
Sbjct: 181 RTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQP 240
Query: 241 YRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGY 300
YRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGY
Sbjct: 241 YRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGY 300
Query: 301 LPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKY 360
LPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKY
Sbjct: 301 LPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKY 360
Query: 361 FTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDY 420
FTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDY
Sbjct: 361 FTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDY 420
Query: 421 YPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGID 480
YPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGID
Sbjct: 421 YPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGID 480
Query: 481 DIRYLFSYDLRWLREAKLIW 500
DIRYLFSYDLRWLREAKLIW
Sbjct: 481 DIRYLFSYDLRWLREAKLIW 500
>pir||C71111 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain - Pyrococcus
horikoshii >gi|3257066|dbj|BAA29749.1| (AP000003) 499aa
long hypothetical phenylalanyl-tRNA synthetase subunit
alpha chain [Pyrococcus horikoshii]
Length = 499
Score = 847 bits (2165), Expect = 0.0
Identities = 412/500 (82%), Positives = 464/500 (92%), Gaps = 1/500 (0%)
Query: 1 MTLGYNEKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIV 60
M LGYNEKLVLL +A+L+ A+VEE++++T LDQVAVMRA+LTL+ +GL K+HE + ++I
Sbjct: 1 MRLGYNEKLVLLKLAELKNATVEELIEKTNLDQVAVMRALLTLQSQGLAKVHEERRRMIK 60
Query: 61 LTDIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKD 120
LT+ GK Y +IGLPEIRAL++L+EK K L++LKDVL ++ELKAIVG+LR+EG A V K
Sbjct: 61 LTETGKRYIEIGLPEIRALKILKEKGKVTLNDLKDVLSDEELKAIVGVLRKEGWAEVSKT 120
Query: 121 EKGLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVE 180
++GL L+++EKG+K +R IDIAL++LS KGEVSV+EI +II VK+LKRRKIA E+E+V
Sbjct: 121 KEGLTLKLSEKGKKAEKRAIDIALEVLS-KGEVSVEEIEKIISVKELKRRKIAEEEEKVI 179
Query: 181 RTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQP 240
R VEIT+KG +LV KGIELKREV+ LTPELI +GKWREVE KPFNIKAPVK+IYPGKKQP
Sbjct: 180 RNVEITDKGLELVEKGIELKREVSILTPELIVTGKWREVEFKPFNIKAPVKKIYPGKKQP 239
Query: 241 YRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGY 300
YRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGY
Sbjct: 240 YRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGY 299
Query: 301 LPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKY 360
LPDE+LVS+VKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSAR+LAKGIEIPGKY
Sbjct: 300 LPDENLVSKVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARELAKGIEIPGKY 359
Query: 361 FTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDY 420
FTIQRVFRPDVLDRTHLIEFNQIDGFVA EDLTFRHLLGILKRFAIEIAGAKKVKFFPDY
Sbjct: 360 FTIQRVFRPDVLDRTHLIEFNQIDGFVASEDLTFRHLLGILKRFAIEIAGAKKVKFFPDY 419
Query: 421 YPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGID 480
YPFTEPSVQLSAYHPELGWVEFGGAG+FREEMTEALGIKVPVIAWGIGIDRLAMFKLG+D
Sbjct: 420 YPFTEPSVQLSAYHPELGWVEFGGAGIFREEMTEALGIKVPVIAWGIGIDRLAMFKLGVD 479
Query: 481 DIRYLFSYDLRWLREAKLIW 500
DIRYLFSYDL+WLRE+KLIW
Sbjct: 480 DIRYLFSYDLKWLRESKLIW 499
>pir||C69199 phenylalanine--tRNA ligase (EC 6.1.1.20) - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621831|gb|AAB85246.1| (AE000853) phenylalanyl-tRNA
synthetase [Methanobacterium thermoautotrophicum]
Length = 511
Score = 330 bits (836), Expect = 3e-89
Identities = 192/496 (38%), Positives = 301/496 (59%), Gaps = 17/496 (3%)
Query: 7 EKLVLLTIAKLEKA-SVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLTDIG 65
EK VL +K EEI + ++D +VM A LE G +++ + ++++ LT+ G
Sbjct: 15 EKKVLKAFEGSDKPLKPEEIAESQKIDIKSVMSASGALESRGFVRVMKDADEVVSLTEDG 74
Query: 66 KEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGI--LRREGLANVRKDEKG 123
+ ++ GLPE R + L+ +++ + EL D+ +A +GI L R+G + +G
Sbjct: 75 ESCAREGLPERRLIEALKGEEELEMSELSRRAGLDKKEAGIGIGWLMRKGWGRI---SQG 131
Query: 124 LVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIID--VKDLKRRKIAREDERVER 181
+V ++++ + G + L+LL E+G V + E+ + +KDLK RK + +++R
Sbjct: 132 MVSAVSDETPERGAD--ERLLELLLERGSVRIRELPDELRGALKDLKGRKGIVDIRKIKR 189
Query: 182 -TVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQP 240
T+E+T +G+KL+ +GIE+ E T++T E + SG WR++ + +NI A +YPGK P
Sbjct: 190 HTIELTTEGRKLLERGIEIVEEATQVTHEHLKSGAWRKLHYRGYNIDAEYPLVYPGKMHP 249
Query: 241 YRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGY 300
R +D+IR +++GF E + ++E+ FWNFD LFQPQ+H ARE DT+ +K P
Sbjct: 250 LRRIIDEIRSIFLKLGFTE-SRGPIVESAFWNFDCLFQPQDHAAREMQDTFYVKNPAVTD 308
Query: 301 LPDESLVSRVKEAHER-GLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGK 359
LP E LV V++AHE G GS GW Y W + A + R H T +SAR L++ E P K
Sbjct: 309 LPCEDLVRAVQDAHETGGSTGSEGWQYEWDRDVARQSVLRTHTTCVSARFLSEN-EPPLK 367
Query: 360 YFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPD 419
F++ RVFR + + HL EF+Q++G VAG+++ FR+LLGIL+ F ++ +V+F P
Sbjct: 368 MFSVGRVFRRETITYKHLPEFHQVEGIVAGDEVNFRNLLGILREFYRKL--GFEVRFRPA 425
Query: 420 YYPFTEPSVQLSAYHPE-LGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLG 478
Y+P+T S + Y PE W+E GGAG+FR E+ E LG++ PV A+G+GI+RLAM +
Sbjct: 426 YFPYTYLSTECEIYLPEKKSWIELGGAGMFRPEVLEPLGVETPVAAFGLGIERLAMIRFD 485
Query: 479 IDDIRYLFSYDLRWLR 494
I DIR L+ DL WLR
Sbjct: 486 IKDIRMLYQSDLGWLR 501
>gi|11499537 phenylalanyl-tRNA synthetase, subunit alpha (pheS) [Archaeoglobus
fulgidus] >gi|7437798|pir||B69494 phenylalanyl-tRNA
synthetase, subunit alpha (pheS) homolog - Archaeoglobus
fulgidus >gi|2648587|gb|AAB89300.1| (AE000968)
phenylalanyl-tRNA synthetase, subunit alpha (pheS)
[Archaeoglobus fulgidus]
Length = 474
Score = 320 bits (811), Expect = 3e-86
Identities = 191/491 (38%), Positives = 286/491 (57%), Gaps = 31/491 (6%)
Query: 8 KLVLLTIAKLEKASV---EEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLTDI 64
K+ L+ + LE EE + + L + AV++A L++ G +++ E LT+
Sbjct: 4 KIELMLLRSLETGKTYTPEEAAELSGLSKDAVLKAAYMLQERGYVRVIENVRTHYSLTEE 63
Query: 65 GKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKDEKGL 124
G+ Y K GLPE + +++ + +DEL+ + E + +G LRR+G V D+
Sbjct: 64 GERYLKEGLPEEKLYSLVKSGVNS-MDELRKRMGR-EFQIALGWLRRKGAVEVEGDK--- 118
Query: 125 VLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVE 184
+ ++ ER AL+ + E VDE + +K L +RK+ + E + +E
Sbjct: 119 --VVPKREPSFDER---AALQAIKEGR--GVDEGT----LKTLMKRKLVTKSETKQVYIE 167
Query: 185 ITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVF 244
+ +K + IEL+ +T LTPE++ G WR + ++I P K IY GK PY
Sbjct: 168 VMKKPE------IELEDIITDLTPEMLLEGTWRGKQFLKYDITIPAKEIYGGKIHPYERI 221
Query: 245 LDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDE 304
+++ R+ +EMGF E+ ++ FWNFDALFQPQ+HPAR+ DT+ Y ++ +
Sbjct: 222 IEECRKVFLEMGFTEIK-GHYVQPAFWNFDALFQPQDHPARDMQDTF---YLDRYIDLEG 277
Query: 305 SLVSRVKEAHERG-LAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTI 363
+V RVK HE G + GS GWG WS E+A L+ R H TA++ LA+ E P K F I
Sbjct: 278 EIVERVKATHENGWITGSTGWGGEWSLEKARQLVLRTHTTAITIHYLAENPEPPQKAFCI 337
Query: 364 QRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPF 423
RV+R + +D THL EF+Q++G V D+ F+HLLG+LK F ++ G + V+F P Y+P+
Sbjct: 338 DRVYRRETIDATHLPEFDQLEGVVLDRDVGFKHLLGLLKEFFTKM-GFEDVRFRPGYFPY 396
Query: 424 TEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDIR 483
TEPSV+ Y LGWVE GGAGVFR+E+TE LGI+ V+AWG+GI RLAM K+G+ D+R
Sbjct: 397 TEPSVEPEVYVEGLGWVELGGAGVFRKEVTEPLGIRGKVLAWGLGIGRLAMLKIGLKDLR 456
Query: 484 YLFSYDLRWLR 494
L+ DL WLR
Sbjct: 457 RLYLPDLGWLR 467
>sp|Q57911|SYF_METJA PROBABLE PHENYLALANYL-TRNA SYNTHETASE (PHENYLALANINE--TRNA LIGASE)
>gi|2129182|pir||G64360 phenylalanine--tRNA ligase (EC
6.1.1.20) alpha chain - Methanococcus jannaschii
>gi|1592293|gb|AAB98478.1| (U67499) phenylalanyl-tRNA
synthetase, subunit alpha (pheS) [Methanococcus
jannaschii]
Length = 480
Score = 316 bits (801), Expect = 4e-85
Identities = 183/469 (39%), Positives = 280/469 (59%), Gaps = 36/469 (7%)
Query: 36 VMRAILTLEKEGLIKLHERKEKIIVLTDIGKEYSKIGLPEIRALRVLREK--KKAYLDEL 93
++R L L+ + L++ E+ +KII L KE PE + L++ K+ + L
Sbjct: 36 ILRVSLWLKGKNLVETEEKVKKIIKLI---KEEE---FPERKIANYLKQHNIKEIEIKNL 89
Query: 94 KDVLREDELKAIVGILRREGLANVRKDEKGLVLEITEKGEKLGERPIDIALKLLSEKGEV 153
KD+L ++E+ A +G ++R+G+A + EKG ++ + L + ++ L L K
Sbjct: 90 KDILPKEEINAALGAIKRKGIARI---EKGKIIF-----DNLDYKDVEEQL-LQKIKENK 140
Query: 154 SVDEIS----RIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREVTRLTPE 209
+D+ S +IID+ LK+R DE E +++TEKGK+ + IE++ E+T+LT +
Sbjct: 141 YLDDFSEEEKKIIDI--LKKRGYVDFDEEKEIKIKLTEKGKEFIKNPIEIEEEITQLTRD 198
Query: 210 LIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQ 269
+I SGKW++ ++P+++K P K IYP K P + +++ L+ MGF E+ ++ET+
Sbjct: 199 IIISGKWKKAYIRPYDVKVPTKPIYPAKVHPLTRIIREVKEILLAMGFKEVK-SPIVETE 257
Query: 270 FWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWS 329
FWNFD LF+PQ+HPARE DT+ LKYP +G +P E L+S+VKE HER W Y +
Sbjct: 258 FWNFDMLFEPQDHPAREMQDTFFLKYPNEGDIP-EDLLSKVKEVHERC------WKYKFD 310
Query: 330 PERAMLLMPRAHATALSARQLAKGIEI----PGKYFTIQRVFRPDVLDRTHLIEFNQIDG 385
+ L+ R H TA S R LA + P K F I RVFR + +D HL EF Q +G
Sbjct: 311 ENVSRRLILRTHTTASSIRYLASLSDEEKNKPHKVFCIDRVFRNEAIDYKHLPEFYQCEG 370
Query: 386 FVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGA 445
+ +++ F +L+G+LK F + G +KV+F P Y+PFTEPS++ Y GW+E GA
Sbjct: 371 IIMDDNVNFNNLIGVLKEFLNRL-GFEKVRFRPAYFPFTEPSLEAEVYLEGKGWLEILGA 429
Query: 446 GVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLR 494
G+FR E+ E +GI+ PV+AWGIG RLAM + G+ DIR L DL WL+
Sbjct: 430 GIFRPEVLEPIGIEKPVLAWGIGFSRLAMLRYGLTDIRDLHKNDLDWLK 478
>gb|AAK40456.1| Phenylalanyl-tRNA synthetase alpha subunit (pheS) [Sulfolobus
solfataricus]
Length = 468
Score = 291 bits (736), Expect = 2e-77
Identities = 177/496 (35%), Positives = 282/496 (56%), Gaps = 35/496 (7%)
Query: 3 LGYNEKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLT 62
L NE +L + L+K + E+ + + + +V+ I L ++G +K + EK VLT
Sbjct: 5 LSENEAKILFFLKDLKKTNSVELAIKMGIPESSVLSLIELLREKGYVKTEVKSEKHYVLT 64
Query: 63 DIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKDEK 122
+ G++ + GLPE + L ++K L+E+K++L +D + +R+GL ++++
Sbjct: 65 EEGRKRKESGLPEDILINTLNGQEKD-LNEIKNILNKD-FNIAISWAKRKGLIDIKE--- 119
Query: 123 GLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERT 182
G+ + + SE +S E + + LK+R + E ER +
Sbjct: 120 -------------GKVIPKVKTYMSSEYLALSNLERADSNTINLLKKRGLIEEKERKIVS 166
Query: 183 VEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYR 242
VE+ ++ K E + ++ L ELI SG+W++ +LK +N++A KK +R
Sbjct: 167 VELIKEPK-------ESEIGISNLNRELIISGEWKKYKLKKYNVEAFPPYYTISKKHYFR 219
Query: 243 VFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLP 302
FL+K++ +I +GF E+ IE +F+NFD LFQPQ+HPARE D++ ++ G +
Sbjct: 220 EFLEKVKDIMISLGFKEINT-GYIEMEFYNFDLLFQPQDHPAREIHDSFSVE--GSGKIE 276
Query: 303 DESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFT 362
D+ L++ VKE HE+ W Y W + + LM R+ TA +AR LA + P K FT
Sbjct: 277 DKDLLNNVKEIHEKF------WKYEWKQDITLRLMLRSQTTATTARVLASRPKAPQKVFT 330
Query: 363 IQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYP 422
+ +VFRPD +D THLIEF+Q+DG + + TF+ LLG+LK + G K+VKF P Y+P
Sbjct: 331 LGKVFRPDAIDATHLIEFHQLDGVIIDNNFTFKELLGVLKEIFYRL-GIKEVKFKPAYFP 389
Query: 423 FTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDI 482
FTEPSV+ Y +LGWVE GAG+ R E+ ++GI AWGIGI+RLAM L I DI
Sbjct: 390 FTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDSTAGAWGIGIERLAMSFLNISDI 449
Query: 483 RYLFSYDLRWLREAKL 498
R L+S ++ ++R+ K+
Sbjct: 450 RLLYSNNIEYIRDTKV 465
>sp|P95961|SYF_SULSO PROBABLE PHENYLALANYL-TRNA SYNTHETASE (PHENYLALANINE--TRNA LIGASE)
>gi|7437796|pir||S75389 probable phenylalanine--tRNA
ligase (EC 6.1.1.20) alpha chain - Sulfolobus
solfataricus >gi|1707794|emb|CAA69551.1| (Y08257)
phenylalanyl-tRNA synthetase alpha chain [Sulfolobus
solfataricus]
Length = 468
Score = 291 bits (736), Expect = 2e-77
Identities = 177/496 (35%), Positives = 282/496 (56%), Gaps = 35/496 (7%)
Query: 3 LGYNEKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLT 62
L NE +L + L+K + E+ + + + +V+ I L ++G +K + EK VLT
Sbjct: 5 LSENEAKILFFLKDLKKTNSVELAIKMGIPESSVLSLIELLREKGYVKTEVKSEKHYVLT 64
Query: 63 DIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKDEK 122
+ G++ + GLPE + L ++K L+E+K++L +D + +R+GL ++++
Sbjct: 65 EEGRKRKESGLPEDILINTLNGQEKD-LNEIKNILNKD-FNIAISWAKRKGLIDIKE--- 119
Query: 123 GLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERT 182
G+ + + SE +S E + + LK+R + E ER +
Sbjct: 120 -------------GKVIPKVKTYMSSEYLALSNLERADSNTINLLKKRGLIEEKERKIVS 166
Query: 183 VEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYR 242
VE+ ++ K E + ++ L ELI SG+W++ +LK +N++A KK +R
Sbjct: 167 VELIKEPK-------ESEIGISNLNRELIISGEWKKYKLKKYNVEAFPPYYTISKKHYFR 219
Query: 243 VFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLP 302
FL+K++ +I +GF E+ IE +F+NFD LFQPQ+HPARE D++ ++ G +
Sbjct: 220 EFLEKVKDIMISLGFKEINT-GYIEMEFYNFDLLFQPQDHPAREIHDSFSVE--GSGKIE 276
Query: 303 DESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFT 362
D+ L++ VKE HE+ W Y W + + LM R+ TA +AR LA + P K FT
Sbjct: 277 DKDLLNNVKEIHEKF------WKYEWKQDITLRLMLRSQTTATTARVLASRPKAPQKVFT 330
Query: 363 IQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYP 422
+ +VFRPD +D THLIEF+Q+DG + + TF+ LLG+LK + G K+VKF P Y+P
Sbjct: 331 LGKVFRPDAIDATHLIEFHQLDGVIIDNNFTFKELLGVLKEIFYRL-GIKEVKFKPAYFP 389
Query: 423 FTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDI 482
FTEPSV+ Y +LGWVE GAG+ R E+ ++GI AWGIGI+RLAM L I DI
Sbjct: 390 FTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDSTAGAWGIGIERLAMSFLNISDI 449
Query: 483 RYLFSYDLRWLREAKL 498
R L+S ++ ++R+ K+
Sbjct: 450 RLLYSNNIEYIRDTKV 465
>sp|O83938|SYFA_TREPA PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7437801|pir||C71257
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain
(pheS) - syphilis spirochete >gi|3323297|gb|AAC65930.1|
(AE001265) phenylalanyl-tRNA synthetase alpha subunit
(pheS) [Treponema pallidum]
Length = 553
Score = 279 bits (705), Expect = 7e-74
Identities = 143/294 (48%), Positives = 187/294 (62%), Gaps = 3/294 (1%)
Query: 202 EVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMT 261
E+ LT E + SG W+ L+ +N+ P RI PG+ Y FL+ I+ RL+ +GF E
Sbjct: 259 EIGALTVECLKSGAWKTQHLRRYNVHIPPARIIPGRSNAYADFLEHIKDRLVALGFQEFD 318
Query: 262 VDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGL-AG 320
L+ET FWN DALF PQ HPAR+ D Y LK+P E +SRV HERG +G
Sbjct: 319 -GPLVETDFWNADALFMPQFHPARDIHDVYYLKHPTHAPTIPEPFLSRVAATHERGADSG 377
Query: 321 SRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEF 380
S GW Y + + L+ R+ TALSAR L IPGKYF I R FR D +D THL +F
Sbjct: 378 SLGWRYSFDRDFTRRLLLRSQGTALSARHLPTA-HIPGKYFGIARCFRHDQVDATHLADF 436
Query: 381 NQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPELGWV 440
Q +G V G D+ LLG+LK A EIAGA++V++ Y+PFTEPS++L A HP LGW
Sbjct: 437 YQTEGIVLGTDVNVCTLLGMLKILATEIAGAQEVRYVGGYFPFTEPSIELHALHPALGWF 496
Query: 441 EFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLR 494
E GGAG+ R E+T+ LG+ VPV+AWG+G+DR+A+ LGI D+R LFS D+ +R
Sbjct: 497 ELGGAGLLRPEVTDPLGVHVPVMAWGLGVDRMALLALGISDVRELFSPDIESVR 550
>sp|P94282|SYFA_BORBU PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7437804|pir||H70163
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain
pheS - Lyme disease spirochete
>gi|2688421|gb|AAC66871.1| (AE001153) phenylalanyl-tRNA
synthetase, alpha subunit (pheS) [Borrelia burgdorferi]
Length = 528
Score = 268 bits (677), Expect = 1e-70
Identities = 182/507 (35%), Positives = 276/507 (53%), Gaps = 56/507 (11%)
Query: 3 LGYNEKLVLLTIAKLE-KASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVL 61
LG+NE TI L K +EEI ++ + A R + L ++G ++ EKII L
Sbjct: 42 LGFNEGQANKTIEWLNSKGIIEEIYRKLNVFYKATERGLGAL-RDGFVE-----EKIINL 95
Query: 62 TDIGKEYSKIGLPEIRALRV---LREKKKAYLDELKDVLREDELKAIVGILRREGLANVR 118
K L AL + ++E +KA+ + LK+ + +L + I +G
Sbjct: 96 VS-----QKAVLASNLALELDIDVKEVRKAFGNLLKEGILSLDLDKQIIINCLDG-TETN 149
Query: 119 KDEKGLVLEITEKGEKLGERPIDIALKLLS----EKGEVSVDEISRIIDVKDLKRRKIAR 174
+ ++LE + + L E L L+S +KG SV +II+ DLK R
Sbjct: 150 YQKVRVLLERAKNSDLLRESLTTEELLLISNFAKKKGADSV--FFKIIEKLDLKFR---- 203
Query: 175 EDERVERTVEITEKGKKLVSKGIELKR----------EVTRLTPELIASGKWREVELKPF 224
L S G+E+K E+T+LTPE++ + + + + +
Sbjct: 204 -----------------LSSFGLEVKNFLMKSKLTGDELTKLTPEILKNKTYENKKFRAY 246
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
NI P + + G+ Y ++ KI+ +L+ +GF E L+ET+F+N DALF PQ HP+
Sbjct: 247 NIHIPSAKTFIGRANSYLDYISKIKDKLVGLGFQEFD-GPLVETEFFNNDALFMPQFHPS 305
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLA-GSRGWGYVWSPERAMLLMPRAHAT 343
R+ D Y + P E S VK AHE G A GSRGW Y +S + + L+ R H T
Sbjct: 306 RDIKDVYYISDPSMQESLPEPYFSNVKLAHETGYATGSRGWRYSFSEDLSKRLVLRTHGT 365
Query: 344 ALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKR 403
LSA+QL + P +YF + R FR D +D TH ++F Q +G V + ++ + LLG+L+
Sbjct: 366 VLSAKQLINA-KNPSRYFGVIRCFRYDQVDATHGVDFYQTEGIVIEDGVSIKTLLGLLEI 424
Query: 404 FAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVI 463
FA E+AGA ++K+ P Y+PFTEPS+++ HP LGW E GG+G+FR E+T+ LGI +PVI
Sbjct: 425 FAKELAGATEIKYVPAYFPFTEPSIEIHVKHPVLGWFELGGSGIFRPEVTKPLGIDLPVI 484
Query: 464 AWGIGIDRLAMFKLGIDDIRYLFSYDL 490
AWGIGIDR+A+ LG++D+R LF+YD+
Sbjct: 485 AWGIGIDRMALMHLGLNDLRDLFTYDI 511
>pir||B72457 probable phenylalanyl-tRNA synthetase alpha chain APE2302 -
Aeropyrum pernix (strain K1) >gi|5106003|dbj|BAA81314.1|
(AP000064) 473aa long hypothetical phenylalanyl-tRNA
synthetase alpha chain [Aeropyrum pernix]
Length = 473
Score = 259 bits (654), Expect = 7e-68
Identities = 175/485 (36%), Positives = 266/485 (54%), Gaps = 23/485 (4%)
Query: 19 KASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLTDIGKEYSKIGLPEIRA 78
+ ++EE K +D+ ++ L ++G++++ ER E+ VLT+ G++ + GLPE +
Sbjct: 8 EGTLEEASKILGVDKSSLASLSNLLAEKGVVEVEERVEEHYVLTERGRDALERGLPEEKL 67
Query: 79 LRVLREKK-KAYLDELKDVLREDELKAIVGILRREGLANVRKDEKGLVLEITEKGEKLGE 137
+ L + +A ++E++ L E E +G R+GL + G+V ++ E L
Sbjct: 68 VLFLAGRGGEASVEEVRRALGE-EAGIALGQAARKGLVVIAG---GVVRLAVDQAEAL-- 121
Query: 138 RPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGI 197
+ I KLL S + + + L R I RE R I + K ++ +
Sbjct: 122 KTITPLKKLLENVASGSKPTVGDELLREALSRGLIRREARR-----SIVLRLKVNPAEAL 176
Query: 198 ELKR-EVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMG 256
R E LT +++ SG+WR + KP+N+KA R+ P ++ F++++R L E+G
Sbjct: 177 ARARVEAAVLTRDMLKSGEWRRLRFKPYNVKAEPPRVLPARRHFLAEFIERLRDILRELG 236
Query: 257 FIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDES-LVSRVKEAHE 315
F E+ L+E + +NFD LFQ Q+HPARE D+ +K P +G L S LV RV HE
Sbjct: 237 FREVR-GPLVELELFNFDVLFQAQDHPAREIHDSLWIKSPRRGDLSGYSDLVERVASVHE 295
Query: 316 RGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRT 375
RG W Y WSPE A + R+ TA+SAR LA P ++FT+ +VFR D + T
Sbjct: 296 RG------WKYRWSPEVASRYILRSQTTAVSARILATRPNPPARFFTVGKVFRSDAVGPT 349
Query: 376 HLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHP 435
L EF+Q+DG E TFR LLG L A + K+KF P Y+PFTEPSV+ P
Sbjct: 350 RLPEFHQLDGIEGDEGYTFRDLLGRLDEIASMLG--LKLKFKPAYFPFTEPSVEGYVKLP 407
Query: 436 ELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLRE 495
W+E GAG+FR E+ EA+G+ PV AWG GI+RLAM G+ DIR L++ ++ +RE
Sbjct: 408 NGRWLELFGAGMFRPEVLEAVGVDYPVGAWGFGIERLAMAFYGVSDIRKLYTRNVDEVRE 467
Query: 496 AKLIW 500
++ W
Sbjct: 468 MRVRW 472
>gb|AAG20567.1| (AE005127) phenylalanyl-tRNA synthetase subunit alpha; PheS
[Halobacterium sp. NRC-1]
Length = 502
Score = 256 bits (647), Expect = 4e-67
Identities = 178/513 (34%), Positives = 263/513 (50%), Gaps = 44/513 (8%)
Query: 14 IAKLEKAS------VEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLTDIGKE 67
+A L+ AS +E + +T + A L LE EGL+ + E + LTD G
Sbjct: 8 VAVLDAASTDDPQRIEALAADTDYPPETIAGAALALEAEGLVAVTETTTTTVSLTDEGHA 67
Query: 68 YSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREG------LANVRKDE 121
Y+ GLPE+R R A LD D E+ +++G +G L+N +
Sbjct: 68 YATDGLPEVRLYR-------AALDAGADD-APVEMGSVIGAAGLDGPQVDIALSNYARKG 119
Query: 122 KGLV----LEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDE 177
G + L + + D AL L++ V D + V L R + E
Sbjct: 120 YGTIDSGALAADPDADPENDPEAD-ALATLTDGDSVDDDAV-----VDQLASRDLVTVSE 173
Query: 178 RVERTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGK 237
R R+V +TE G + G+E EV LTPEL+ASG+W +VE +N+ A PGK
Sbjct: 174 RTVRSVTLTEAGVTELMAGVEATDEVGELTPELLASGEWADVEFADYNVAADAADHTPGK 233
Query: 238 KQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPE 297
R +++ L+ MGF EM ++ F+ D LF PQ+HPAR D + L P
Sbjct: 234 THVLRQAAERVTDVLVGMGFQEM-AGPHVDADFYINDCLFMPQDHPARNHWDRFALSNPA 292
Query: 298 K-GYLPDESLVSRVKEAHERGLAGSRGWGY--VWSPERAMLLMPRAHATALSARQLA--- 351
+ LPD +LV RV+ AH G AG G GY W + A L R H T+L+AR LA
Sbjct: 293 RIDELPD-ALVERVERAHREG-AGDDGDGYHSPWDEDFARALALRGHTTSLTARHLAGLA 350
Query: 352 -KGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAG 410
+E P +YF++++ +R D LD THL+EF QI+G+V +DL+ R L+G + F + G
Sbjct: 351 DADVEAPARYFSVEKAYRNDTLDATHLLEFFQIEGWVLADDLSVRDLMGTFREFYSQF-G 409
Query: 411 AKKVKFFPDYYPFTEPSVQLSAYHPELG-WVEFGGAGVFREEMTEALGIKVPVIAWGIGI 469
++F P Y P+TEPS +L HPE G +E G +G+FR EM + L + V+AWG+ +
Sbjct: 410 IHDLQFKPTYNPYTEPSFELFGRHPETGELIEIGNSGIFRPEMLDPLDVDGDVMAWGLAL 469
Query: 470 DRLAMFKLGIDDIRYLFS--YDLRWLREAKLIW 500
+RL M G +DIR + D+ +LR A++++
Sbjct: 470 ERLLMLMTGFEDIRDVHGTLCDVGFLRNAEVVY 502
>dbj|BAA95666.1| (D84471) phenylalanyl tRNA synthetase beta subunit [Homo sapiens]
Length = 508
Score = 246 bits (621), Expect = 5e-64
Identities = 170/481 (35%), Positives = 253/481 (52%), Gaps = 41/481 (8%)
Query: 24 EIVKETRLDQVAVMRAILTLEKEG-LIKLHERKEKIIVLTDIGKEYSKIGLPEIRALRVL 82
E+ E ++ AV+ A+ +L+ G +I+ R K LT G+E ++ G E R R +
Sbjct: 25 ELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSI 84
Query: 83 REKKKAYLDELKDVLREDELKAIVGILRREGLANVRKDEKGL----VLEITEKGEKLGER 138
+ A +++R K VG + +R D+ V + + E +R
Sbjct: 85 PPEGLAQ----SELMRLPSGK--VGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQR 138
Query: 139 PIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKG-- 196
+ + +EK + E R +L++RK+ E+T K VSKG
Sbjct: 139 RLQLVRGGQAEK----LGEKER----SELRKRKLL---------AEVTLK-TYWVSKGGA 180
Query: 197 --IELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIE 254
+ ++ T L+PE+I+SG WR+ KP+N A G P + R+ +E
Sbjct: 181 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE 240
Query: 255 MGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAH 314
MGF EM D+ IE+ FWNFDALFQPQ HPAR+ DT+ L+ P + V RVK H
Sbjct: 241 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH 300
Query: 315 ERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIE----IPGKYFTIQRVFRPD 370
+G GS+G+ Y W + A + R H T+ SAR L + + P KYF+I RVFR +
Sbjct: 301 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE 360
Query: 371 VLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQL 430
LD THL EF+QI+G VA LT HL+G+L+ F ++ G +++F P Y P+TEPS+++
Sbjct: 361 TLDATHLAEFHQIEGLVADHGLTLGHLMGVLREFFTKL-GITQLRFKPAYNPYTEPSMEV 419
Query: 431 SAYHPEL-GWVEFGGAGVFREEMTEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLFS 487
+YH L WVE G +GVFR EM +G+ V VIAWG+ ++R M K GI++IR L
Sbjct: 420 FSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVG 479
Query: 488 Y 488
+
Sbjct: 480 H 480
>gi|4758340 phenylalanine-tRNA synthetase-like protein [Homo sapiens]
>gi|11525941|ref|XP_009056.1| phenylalanine-tRNA
synthetase-like protein [Homo sapiens]
>gi|2102679|gb|AAB61694.1| (U07424) putative tRNA
synthetase-like protein [Homo sapiens]
>gi|4104935|gb|AAD02221.1| (AF042347) putative
phenylalanyl-tRNA synthetase alpha-subunit; PheHA [Homo
sapiens]
Length = 508
Score = 245 bits (620), Expect = 6e-64
Identities = 170/481 (35%), Positives = 253/481 (52%), Gaps = 41/481 (8%)
Query: 24 EIVKETRLDQVAVMRAILTLEKEG-LIKLHERKEKIIVLTDIGKEYSKIGLPEIRALRVL 82
E+ E ++ AV+ A+ +L+ G +I+ R K LT G+E ++ G E R R +
Sbjct: 25 ELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSI 84
Query: 83 REKKKAYLDELKDVLREDELKAIVGILRREGLANVRKDEKGL----VLEITEKGEKLGER 138
+ A +++R K VG + +R D+ V + + E +R
Sbjct: 85 PPEGLAQ----SELMRLPSGK--VGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQR 138
Query: 139 PIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKG-- 196
+ + +EK + E R +L++RK+ E+T K VSKG
Sbjct: 139 RLQLVRGGQAEK----LGEKER----SELRKRKLL---------AEVTLK-TYWVSKGSA 180
Query: 197 --IELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIE 254
+ ++ T L+PE+I+SG WR+ KP+N A G P + R+ +E
Sbjct: 181 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE 240
Query: 255 MGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAH 314
MGF EM D+ IE+ FWNFDALFQPQ HPAR+ DT+ L+ P + V RVK H
Sbjct: 241 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH 300
Query: 315 ERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIE----IPGKYFTIQRVFRPD 370
+G GS+G+ Y W + A + R H T+ SAR L + + P KYF+I RVFR +
Sbjct: 301 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE 360
Query: 371 VLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQL 430
LD THL EF+QI+G VA LT HL+G+L+ F ++ G +++F P Y P+TEPS+++
Sbjct: 361 TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL-GITQLRFKPAYNPYTEPSMEV 419
Query: 431 SAYHPEL-GWVEFGGAGVFREEMTEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLFS 487
+YH L WVE G +GVFR EM +G+ V VIAWG+ ++R M K GI++IR L
Sbjct: 420 FSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVG 479
Query: 488 Y 488
+
Sbjct: 480 H 480
>emb|CAC11777.1| (AL445064) phenylalanine--tRNA ligase beta chain related protein
[Thermoplasma acidophilum]
Length = 499
Score = 244 bits (617), Expect = 1e-63
Identities = 156/495 (31%), Positives = 249/495 (49%), Gaps = 35/495 (7%)
Query: 7 EKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLTDIGK 66
E VL I ++E + L + AI LE +GL+ + R+ K L+ GK
Sbjct: 14 EYRVLRAIQSRGATAIESELSVEGLSDREIASAISWLEVKGLLDVERREIKTYALSSEGK 73
Query: 67 EYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIV-----GILRREGLANVRKDE 121
Y + GLPE+ R L+E+ + +DE++D++ + A+ GI +EG R
Sbjct: 74 RYLREGLPELVLYRKLKERGEMTMDEIRDLMPDTYRIALAQLAKFGITPKEGKLIYRNS- 132
Query: 122 KGLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEI---SRIIDVKDLKRRKIAREDER 178
G+ I E+ L+ + K +D S +ID K R + D
Sbjct: 133 -GIEAAIEERQR---------FLQSMDPKNTAMIDHFRHRSGVIDEKIRTERIVRLNDSA 182
Query: 179 VERTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKK 238
E E +G + L P +IASG+W+ + +++ +P I K
Sbjct: 183 YEAIAEFGGEGL------------IGSLDPSIIASGEWKTKNFRKYDLNSPSSVIRSSLK 230
Query: 239 QPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEK 298
P +++IR + MGF EM IE+ W+ D+LF PQ+HPAR+ DT+ ++ +
Sbjct: 231 HPMTYLIEEIREIFLNMGFTEMG-GHYIESTLWDMDSLFIPQDHPARDMQDTFYVE-ADS 288
Query: 299 GYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPG 358
+ + ++++ HE+G G GWGY WS A L+ R H T +AR L + E P
Sbjct: 289 FDIDHPEISKKIRKIHEKGFDGYSGWGYRWSDAEARKLVLRTHTTVSTARYLYENNEPPQ 348
Query: 359 KYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFP 418
F++++VFR + +D HL EF QI+G V +D++ L IL+ F ++ G +K P
Sbjct: 349 AIFSVEKVFRHESVDWKHLAEFYQIEGAVYSKDVSVSTLKWILRDFYAKL-GFNDIKLIP 407
Query: 419 DYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLG 478
YYP+TEPS+ + VE GG+G+FR E+ + LG+K PV+AWG+G++RLAM G
Sbjct: 408 SYYPYTEPSLDV-VVRVNGKEVELGGSGLFRPEVLKILGLKAPVMAWGMGLERLAMMYYG 466
Query: 479 IDDIRYLFSYDLRWL 493
+ D+R L++ D +L
Sbjct: 467 LTDVRDLYNTDFEFL 481
>pir||T45074 probable phenylalanine--tRNA ligase (EC 6.1.1.20) [imported] -
human >gi|1905910|gb|AAB51175.1| (AD000092) putative
human phenylalanine tRNA synthetase [Homo sapiens]
Length = 463
Score = 242 bits (612), Expect = 6e-63
Identities = 165/472 (34%), Positives = 247/472 (51%), Gaps = 51/472 (10%)
Query: 31 LDQVAVMRAILTLEKEG-LIKLHERKEKIIVLTDIGKEYSKIGLPEIRALRVLREKKKAY 89
++ AV+ A+ +L+ G +I+ R K LT G+E ++ G E R R + + A
Sbjct: 1 MEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSIPPEGLAQ 60
Query: 90 LDELKDVLREDELKAIVGILRREGLANVRKDEKGLVLEITEKG--EKLGERPIDIALKLL 147
+ ++ L ++ + + + +DE L++ G EKLGE+
Sbjct: 61 SELMR--LPSGKVGFSKAMSNKWIRVDSMEDEVQRRLQLVRGGQAEKLGEK--------- 109
Query: 148 SEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKG----IELKREV 203
+ +L++RK+ E+T K VSKG + ++
Sbjct: 110 ---------------ERSELRKRKLL---------AEVTLK-TYWVSKGSAFSTSISKQE 144
Query: 204 TRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVD 263
T L+PE+I+SG WR+ KP+N A G P + R+ +EMGF EM D
Sbjct: 145 TELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTD 204
Query: 264 SLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRG 323
+ IE+ FWNFDALFQPQ HPAR+ DT+ L+ P + V RVK H +G GS+G
Sbjct: 205 NFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQG 264
Query: 324 WGYVWSPERAMLLMPRAHATALSARQLAKGIE----IPGKYFTIQRVFRPDVLDRTHLIE 379
+ Y W + A + R H T+ SAR L + + P KYF+I RVFR + LD THL E
Sbjct: 265 YKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAE 324
Query: 380 FNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPEL-G 438
F+QI+G VA LT HL+G+L+ F ++ G +++F P Y P+TEPS+++ +YH L
Sbjct: 325 FHQIEGVVADHGLTLGHLMGVLREFFTKL-GITQLRFKPAYNPYTEPSMEVFSYHQGLKK 383
Query: 439 WVEFGGAGVFREEMTEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLFSY 488
WVE G +GVFR EM +G+ V VIAWG+ ++R M K GI++IR L +
Sbjct: 384 WVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH 435
>pir||T28752 phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain T08B2.9
[similarity] - Caenorhabditis elegans
>gi|9803007|gb|AAG00015.1| (AF000263) Similar to
phenylalanyl-tRNA synthetase; coded for by C. elegans
cDNA CEESP75F; coded for by C. elegans cDNA CEESV94F;
coded for by C. elegans cDNA CEMSA02F; coded for by C.
elegans cDNA CEMSA02R; coded for by C. elegans cDNA
cm02c4; coded f>
Length = 552
Score = 238 bits (600), Expect = 1e-61
Identities = 158/470 (33%), Positives = 242/470 (50%), Gaps = 30/470 (6%)
Query: 24 EIVKETRLDQVAVMRAILTL-EKEGLIKLHERKEKIIVLTDIGKEYSKIGLPEIRALRVL 82
++ ++ LD V+ AI +L EG++ + EK + LT+ G +++ G PE +
Sbjct: 87 QLAQQWNLDHQKVIGAIKSLLANEGVLTTKDVTEKRLELTNEGVQFANEGSPEYLVFEFV 146
Query: 83 REKKKAYLDELKDVLREDELKAIVGILRREGLANVRKDEKGLVLEITEKGEKLGERPIDI 142
A D K + +G+ + V D+ +V + TE + ++ +
Sbjct: 147 GTDGAAQADIQKKPFGK------IGMAKAMQFKWVSVDKGRVVRQATEVTDSTRKQLESL 200
Query: 143 ALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKRE 202
+ G V E + K+LK+RK+ E V + KG + L ++
Sbjct: 201 RI------GSSDVSENEK----KELKKRKLISE---VNIKALVVSKGTSFTTS---LAKQ 244
Query: 203 VTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTV 262
LTPE+IASG W++++ K +N + G P + R+ MGF EM
Sbjct: 245 EADLTPEMIASGSWKDMQFKKYNFDSLGVVPSSGHLHPLMKVRSEFRQIFFSMGFSEMAT 304
Query: 263 DSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSR 322
+ +E+ FWNFDALFQPQ HPAR+ DT+ + P E + RVK H +G GS
Sbjct: 305 NRYVESSFWNFDALFQPQQHPARDAHDTFFVSDPAISTKFPEDYLERVKTVHSKGGYGSA 364
Query: 323 GWGYVWSPERAMLLMPRAHATALSAR---QLAKGIEIPGKYFTIQRVFRPDVLDRTHLIE 379
G+ Y W E A + R H TA+SAR QLA+ P K F+I RVFR + LD THL E
Sbjct: 365 GYNYDWKIEEAQKNVLRTHTTAVSARQLYQLAQEGFRPSKLFSIDRVFRNETLDATHLAE 424
Query: 380 FNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPEL-G 438
F+Q++G +A ++L+ HL+GI F ++ G ++F P Y P+TEPS+++ AYH L
Sbjct: 425 FHQVEGVIAEKNLSLAHLIGIFTEFFKKL-GITNLRFKPTYNPYTEPSMEIFAYHQGLTK 483
Query: 439 WVEFGGAGVFREEMTEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLF 486
WVE G +G+FR EM +G+ V V +G+ ++R M K GI++IR LF
Sbjct: 484 WVEIGNSGMFRPEMLLPMGLPADVNVAGYGLSLERPTMIKYGINNIRDLF 533
>gb|AAF46332.1| (AE003443) CG2263 gene product [Drosophila melanogaster]
Length = 498
Score = 231 bits (582), Expect = 2e-59
Identities = 133/350 (38%), Positives = 199/350 (56%), Gaps = 25/350 (7%)
Query: 163 DVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREVTRL----TPELIASGKWRE 218
+V D K+RK+ +E T ++++G E +T+L T E++A+G W +
Sbjct: 154 EVADFKKRKLLQE----------TTTKSFVLARGPEFATTLTKLETDLTVEMLANGLWDQ 203
Query: 219 VELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQ 278
++ K +N A G P + R+ +EMGF EM ++ +E+ FWNFDAL+Q
Sbjct: 204 LKFKAYNFDALGAPPTRGHLHPLLKVRTEFRQIFLEMGFSEMPTNNYVESSFWNFDALYQ 263
Query: 279 PQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMP 338
PQ HPAR+ DT+ + +P K + + + RVK+ H G GS+G+GY W E A +
Sbjct: 264 PQQHPARDAHDTFFVNHPAKSHKFPQDYLERVKKVHSVGGYGSKGYGYDWKLEEAQKNLL 323
Query: 339 RAHATALSARQLAKGIEIPG-----KYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLT 393
R H TA+SAR L K G KYF+I +VFR + LD THL EF+Q++G +A LT
Sbjct: 324 RTHTTAVSARMLYKLANQEGGFKAAKYFSIDKVFRNETLDATHLAEFHQVEGVIADVGLT 383
Query: 394 FRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPELG-WVEFGGAGVFREEM 452
L+G L F ++ G +++F P Y P+TEPS+++ YHP L W+E G +GVFR EM
Sbjct: 384 LGDLIGTLYEFFRKL-GITQLEFKPAYNPYTEPSMEIFCYHPGLAKWIEVGNSGVFRPEM 442
Query: 453 TEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLF--SYDLRWLREAKL 498
+G+ V VIAWG+ ++R M K GI++IR L DL+ + E +
Sbjct: 443 LLPMGLPENVNVIAWGLSLERPTMIKYGINNIRDLVGPKVDLKMVEEGPI 492
>gb|AAA35152.1| (J03965) Phe-RNA synthetase [Saccharomyces cerevisiae]
Length = 503
Score = 221 bits (558), Expect = 1e-56
Identities = 147/458 (32%), Positives = 246/458 (53%), Gaps = 33/458 (7%)
Query: 49 IKLHERKE--KIIVLT-DIGKEYSKI---GLPEIRALRVLREKKKAYLDELKDVLREDEL 102
+K H + E K+ +T D+ KE ++I G EI+ +++++E + + ++ L
Sbjct: 40 LKAHNKLEFSKVDTVTYDLTKEGAQILNEGSYEIKLVKLIQELGQLQIKDVMSKLGPQVG 99
Query: 103 KAIVGILRREGLANVRKDEKG-LVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRI 161
K VG R + K+ L L + L E + L K +D I
Sbjct: 100 K--VGQARAFKNGWIAKNASNELELSAKLQNTDLNELTDETQSILAQIKNNSHLDSIDAK 157
Query: 162 IDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREVTRL----TPELIASGKWR 217
I + DLK+RK+ + + + +V +KG E ++T+L T +++++ ++
Sbjct: 158 I-LNDLKKRKLIAQGKITDFSV----------TKGPEFSTDLTKLETDLTSDMVSTNAYK 206
Query: 218 EVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALF 277
+++ KP+N + +I G P ++ R+ MGF EM + +ET FWNFDAL+
Sbjct: 207 DLKFKPYNFNSQGVQISSGALHPLNKVREEFRQIFFSMGFTEMPSNQYVETGFWNFDALY 266
Query: 278 QPQNHPAREWTDTYQLKYPEKGYLPDE-SLVSRVKEAHERGLAGSRGWGYVWSPERAMLL 336
PQ HPAR+ DT+ +K P LPD+ + + +K HE+G GS G+ Y W PE L
Sbjct: 267 VPQQHPARDLQDTFYIKDPLTAELPDDKTYMDNIKAVHEQGRFGSIGYRYNWKPEECQKL 326
Query: 337 MPRAHATALSAR---QLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLT 393
+ R H+TA+SAR LAK + P + F+I RVFR + +D THL EF+Q++G +A ++T
Sbjct: 327 VLRTHSTAISARMLHDLAKDPK-PTRLFSIDRVFRNEAVDATHLAEFHQVEGVLADYNIT 385
Query: 394 FRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPEL-GWVEFGGAGVFREEM 452
L+ ++ F E G ++F P Y P+TEPS+++ ++H L WVE G +G+FR EM
Sbjct: 386 LGDLIKFMEEF-FERMGVTGLRFKPTYNPYTEPSMEIFSWHEGLQKWVEIGNSGMFRPEM 444
Query: 453 TEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLFSY 488
E++G+ + V+ WG+ ++R M K + +IR L +
Sbjct: 445 LESMGLPKDLRVLGWGLSLERPTMIKYKVQNIRELLGH 482
>gi|6321087 Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic; Frs2p
[Saccharomyces cerevisiae]
>gi|1174509|sp|P15625|SYFB_YEAST PHENYLALANYL-TRNA
SYNTHETASE BETA CHAIN CYTOPLASMIC (PHENYLALANINE--TRNA
LIGASE BETA CHAIN) >gi|2144559|pir||YFBYAC
phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain,
cytosolic [validated] - yeast (Saccharomyces cerevisiae)
>gi|836732|dbj|BAA09216.1| (D50617) cytoplasmic
phenylalanyl-tRNA synthetase beta chain [Saccharomyces
cerevisiae]
Length = 503
Score = 221 bits (557), Expect = 2e-56
Identities = 149/458 (32%), Positives = 247/458 (53%), Gaps = 33/458 (7%)
Query: 49 IKLHERKE--KIIVLT-DIGKEYSKI---GLPEIRALRVLREKKKAYLDELKDVLREDEL 102
+K H + E K+ +T D+ KE ++I G EI+ +++++E + + ++ L
Sbjct: 40 LKAHNKLEFSKVDTVTYDLTKEGAQILNEGSYEIKLVKLIQELGQLQIKDVMSKLGPQVG 99
Query: 103 KAIVGILRREGLANVRKDEKG-LVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRI 161
K VG R + K+ L L + L E + L K +D I
Sbjct: 100 K--VGQARAFKNGWIAKNASNELELSAKLQNTDLNELTDETQSILAQIKNNSHLDSIDAK 157
Query: 162 IDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREVTRL----TPELIASGKWR 217
I + DLK+RK+ + + IT+ V+KG E ++T+L T +++++ ++
Sbjct: 158 I-LNDLKKRKLIAQGK-------ITDFN---VTKGPEFSTDLTKLETDLTSDMVSTNAYK 206
Query: 218 EVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALF 277
+++ KP+N + +I G P ++ R+ MGF EM + +ET FWNFDAL+
Sbjct: 207 DLKFKPYNFNSQGVQISSGALHPLNKVREEFRQIFFSMGFTEMPSNQYVETGFWNFDALY 266
Query: 278 QPQNHPAREWTDTYQLKYPEKGYLPDE-SLVSRVKEAHERGLAGSRGWGYVWSPERAMLL 336
PQ HPAR+ DT+ +K P LPD+ + + +K HE+G GS G+ Y W PE L
Sbjct: 267 VPQQHPARDLQDTFYIKDPLTADLPDDKTYMDNIKAVHEQGRFGSIGYRYNWKPEECQKL 326
Query: 337 MPRAHATALSAR---QLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLT 393
+ R H+TA+SAR LAK + P + F+I RVFR + +D THL EF+Q++G +A ++T
Sbjct: 327 VLRTHSTAISARMLHDLAKDPK-PTRLFSIDRVFRNEAVDATHLAEFHQVEGVLADYNIT 385
Query: 394 FRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPEL-GWVEFGGAGVFREEM 452
L+ ++ F E G ++F P Y P+TEPS+++ ++H L WVE G +G+FR EM
Sbjct: 386 LGDLIKFMEEF-FERMGVTGLRFKPTYNPYTEPSMEIFSWHEGLQKWVEIGNSGMFRPEM 444
Query: 453 TEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLFSY 488
E++G+ + V+ WG+ ++R M K + +IR L +
Sbjct: 445 LESMGLPKDLRVLGWGLSLERPTMIKYKVQNIRELLGH 482
>pir||T11642 phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain [similarity] -
fission yeast (Schizosaccharomyces pombe)
>gi|3845469|emb|CAA15915.1| (AL021046) phenylalanyl-trna
synthetase beta chain cytoplasmic [Schizosaccharomyces
pombe]
Length = 499
Score = 217 bits (548), Expect = 2e-55
Identities = 162/495 (32%), Positives = 247/495 (49%), Gaps = 37/495 (7%)
Query: 8 KLVLLTIAKLEKASVEEIVKET--------RLDQVAVMRAILTLEKEGLIKLHERKEKII 59
KL L + LEK + + + T +L AIL+L + +I+ + +I
Sbjct: 3 KLEALQVFLLEKLNEKNEIPNTSHLEFDGKKLGPQEAQSAILSLAAKNMIEFSRHEIEIY 62
Query: 60 VLTDIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRK 119
LT G+ G E + + L ELK +G G+ R
Sbjct: 63 NLTAEGENICANGSHEAKVYNEICASMSG--------LNIGELKKKLG--NSAGIGQGRA 112
Query: 120 DEKGLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERV 179
+ G + + +K K + D K+LSE E S+ + DLK+RK+ V
Sbjct: 113 FKLGWIKKDGDKLVKNTDSITDETPKVLSEIKEHGTISDSKTLT--DLKKRKL------V 164
Query: 180 ERTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQ 239
ER + +K + +++++ T LT E+I S W + K +N A G
Sbjct: 165 ERNKIMYFSLRKGPNFSLQIEKLNTDLTAEMITSRSWESAKFKSYNFAAEGIPPAGGCLH 224
Query: 240 PYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYP-EK 298
P ++ R+ E+GF EM ++ +E+ FWNFDALF PQ H AR+ DT+ LK P
Sbjct: 225 PLMKVREEFRKFFFELGFEEMPTNNFVESGFWNFDALFVPQQHSARDAQDTFFLKVPAST 284
Query: 299 GYLPDESLVSRVKEAHERGLAGSRGWGY--VWSPERAMLLMPRAHATALSARQLAKGIE- 355
LPD V+RVK HE G ++G GY +S E L+ R H TA+SA L K +
Sbjct: 285 DKLPDPEYVARVKATHENG-GETKGIGYRAPFSLEETRKLVLRTHTTAVSANMLYKLAQN 343
Query: 356 --IPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKK 413
P KYF+I RVFR + +D THL EF+Q++G + ++T L+G L+ F ++ K
Sbjct: 344 GFHPAKYFSIDRVFRNETVDATHLAEFHQVEGVICDRNITLGDLIGFLEVFFGKM-NVKN 402
Query: 414 VKFFPDYYPFTEPSVQLSAYHPELG-WVEFGGAGVFREEMTEALGI--KVPVIAWGIGID 470
++F P Y P+TEPS+++ +YH +LG WVE G +G+FR EM E +G+ V + +G+ ++
Sbjct: 403 LRFKPAYNPYTEPSLEVFSYHEKLGKWVEVGNSGMFRPEMLEPMGLPKDVRCLGFGLSLE 462
Query: 471 RLAMFKLGIDDIRYL 485
R M K G+ DIR L
Sbjct: 463 RPTMIKYGVADIRQL 477
>pir||T08576 phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain T22F8.180
[similarity] - Arabidopsis thaliana
>gi|4914440|emb|CAB43643.1| (AL050351) phenylalanyl-trna
synthetase-like protein [Arabidopsis thaliana]
>gi|7270911|emb|CAB80591.1| (AL161594) phenylalanyl-trna
synthetase-like protein [Arabidopsis thaliana]
Length = 428
Score = 195 bits (491), Expect = 9e-49
Identities = 143/467 (30%), Positives = 222/467 (46%), Gaps = 86/467 (18%)
Query: 28 ETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLTDIGKEYSKIGLPEIRALRVLREKKK 87
E +D ++ I +L I + + K++ +LTD GK+Y+ G PE++ + E+
Sbjct: 25 EFNIDHNELVNVIKSLHGFRYIDVQDIKKETWILTDEGKKYAAEGSPEVQLFLAVPEEGS 84
Query: 88 AYLDELKDVLREDELKAIVGILRREGLANVRKDEKGLVLEITEKGEKLGERPIDIALKLL 147
DEL+ K + + + G + K++ E G+++ + D+ K+
Sbjct: 85 ISKDELQ--------KKLAPAVFKIGCSQAGKNKW------VEMGKQVSRKVKDVEDKVK 130
Query: 148 SEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREVTRLT 207
+ ++ ++ ++ ++ K + KK + E K+ T LT
Sbjct: 131 GQLLQIQQGKLISLLLLRIWKGYSV-----------------KKGPNYAPERKKVATDLT 173
Query: 208 PELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIE 267
E + + W+E+E K +N KA K P
Sbjct: 174 RENLQN--WKELEFKEYNFKA--------KGAP--------------------------- 196
Query: 268 TQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYV 327
PQ HPAR+ DT+ LK P E V RVK HE G GSRG+ Y
Sbjct: 197 -----------PQQHPARDSHDTFFLKVPSTTRTLPEDYVERVKRVHESGGYGSRGYNYD 245
Query: 328 WSPERAMLLMPRAHATALSARQ---LAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQID 384
W E A + R H TA+S+R LA+ +P KYF+I RVFR + +DRTHL EF+QI+
Sbjct: 246 WKREEANKNLLRTHTTAVSSRMLYALAQKPFVPKKYFSIDRVFRNEAVDRTHLAEFHQIE 305
Query: 385 GFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPELG-WVEFG 443
G + LT L+G+L+ F + G K++F P Y P+TEPS+++ +YH LG WVE G
Sbjct: 306 GLICDRGLTLGDLIGVLEDFFSRL-GMSKLRFKPAYNPYTEPSMEIFSYHEGLGKWVEIG 364
Query: 444 GAGVFREEMTEALGI--KVPVIAWGIGIDRLAMFKLGIDDIRYLFSY 488
+G+FR EM +G+ V VIAWG+ ++R M GID+IR LF +
Sbjct: 365 NSGMFRPEMLLPMGLPEDVRVIAWGLSLERPTMILYGIDNIRDLFGH 411
>gb|AAB41018.1| (U82978) phenylalanyl-tRNA synthetase alpha subunit [Borrelia
burgdorferi]
Length = 413
Score = 142 bits (354), Expect = 1e-32
Identities = 126/404 (31%), Positives = 196/404 (48%), Gaps = 56/404 (13%)
Query: 3 LGYNEKLVLLTIAKLE-KASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVL 61
LG+NE TI L K +EEI ++ + A R + L ++G ++ EKII L
Sbjct: 37 LGFNEGQANKTIEWLNSKGIIEEIYRKLNVFYKATERGLGAL-RDGFVE-----EKIINL 90
Query: 62 TDIGKEYSKIGLPEIRALRV---LREKKKAYLDELKDVLREDELKAIVGILRREGLANVR 118
K L AL + ++E +KA+ + LK+ + +L + I +G +
Sbjct: 91 VS-----QKAVLASNLALELDIDVKEVRKAFGNLLKEGILSLDLDKQIIINCLDG-SETN 144
Query: 119 KDEKGLVLEITEKGEKLGERPIDIALKLLS----EKGEVSVDEISRIIDVKDLKRRKIAR 174
+ ++LE + + L E L L+S +KG SV +II+ DLK R
Sbjct: 145 YQKVRVLLERAKNSDLLRESLTTEELLLISNFAKKKGADSV--FFKIIEKLDLKFR---- 198
Query: 175 EDERVERTVEITEKGKKLVSKGIELKR----------EVTRLTPELIASGKWREVELKPF 224
L S G+E+K E+T+LTPE++ + + + + +
Sbjct: 199 -----------------LSSFGLEVKNFLMKSKLTGDELTKLTPEILKNKTYENKKFRAY 241
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
NI P + + G+ Y ++ KI+ +L+ +GF E L+ET+F+N DALF PQ HP+
Sbjct: 242 NIHIPSAKTFIGRANSYLDYISKIKDKLVGLGFQEFD-GPLVETEFFNNDALFMPQFHPS 300
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLA-GSRGWGYVWSPERAMLLMPRAHAT 343
R+ D Y + P E S VK AHE G A GSRGW Y +S + + L+ R H T
Sbjct: 301 RDIKDVYYISDPSMQESLPEPYFSNVKLAHETGYATGSRGWRYSFSEDLSKRLVLRTHGT 360
Query: 344 ALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFV 387
LSA+QL + P +YF + R FR D +D TH ++F Q +G +
Sbjct: 361 VLSAKQLINA-KNPSRYFGVIRCFRYDQVDATHGVDFYQTEGLL 403
>sp|P27001|SYFA_THETH PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|281500|pir||S22366
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Thermus aquaticus >gi|7245469|pdb|1EIY|A Chain A, The
Crystal Structure Of Phenylalanyl-Trna Synthetase From
Thermus Thermophilus Complexed With Cognate Trnaphe
>gi|2781285|pdb|1PYS|A Chain A, Phenylalanyl-Trna
Synthetase From Thermus Thermophilus
>gi|6980402|pdb|1B7Y|A Chain A, Phenylalanyl Trna
Synthetase Complexed With Phenylalaninyl- Adenylate
>gi|7245814|pdb|1B70|A Chain A, Phenylalanyl Trna
Synthetase Complexed With Phenylalanine
>gi|48251|emb|CAA46559.1| (X65609) phenylalanine--tRNA
ligase [Thermus thermophilus] >gi|48254|emb|CAA78104.1|
(Z12118) Phenylalanyl tRNA Synthetase,alpha subunit
[Thermus thermophilus] >gi|2624413|emb|CAA75644.1|
(Y15464) phenylalanyl-tRNA synthetase (alpha subunit)
[Thermus thermophilus]
Length = 350
Score = 120 bits (297), Expect = 5e-26
Identities = 102/371 (27%), Positives = 175/371 (46%), Gaps = 56/371 (15%)
Query: 156 DEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKR----EVTRLTPELI 211
+ ++ I + +DL+ K A + + + +T++ K L + +E +R E+ + L
Sbjct: 4 EALAAIQNARDLEELK-ALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAALE 62
Query: 212 ASGKWREVELKPFNIKAPVKR-----------IYPGKKQPYRVFLDKIRRRLIEMGFIEM 260
A+ + RE L+ +K ++R ++ G P + ++ +G+ +
Sbjct: 63 AALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGY-QA 121
Query: 261 TVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAG 320
+E++F+NFDAL P++HPAR+ DT+ L +G+ + L V+
Sbjct: 122 VEGPEVESEFFNFDALNIPEHHPARDMWDTFWLT--GEGFRLEGPLGEEVEGR------- 172
Query: 321 SRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEF 380
L+ R H + + R + P + RVFR + D TH F
Sbjct: 173 ---------------LLLRTHTSPMQVRYMVAHTP-PFRIVVPGRVFRFEQTDATHEAVF 216
Query: 381 NQIDGFVAGEDLTFRHLLGILKRFAIEIAGA-KKVKFFPDYYPFTEPSVQLSAYHPELG- 438
+Q++G V GE + HL G + A + G KV+F P Y+PF EP Q + + PE G
Sbjct: 217 HQLEGLVVGEGIAMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWWPEGGK 276
Query: 439 WVEFGGAGVFREEMTEA-------LGIK-----VPVIAWGIGIDRLAMFKLGIDDIRYLF 486
W+E GGAG+ ++ +A LG+ V A+G+G++RLAM + GI DIRY F
Sbjct: 277 WLELGGAGMVHPKVFQAVDAYRERLGLPPAYRGVTGFAFGLGVERLAMLRYGIPDIRYFF 336
Query: 487 SYDLRWLREAK 497
L++L + K
Sbjct: 337 GGRLKFLEQFK 347
>dbj|BAB06830.1| (AP001517) phenylalanyl-tRNA synthetase alpha subunit [Bacillus
halodurans]
Length = 344
Score = 114 bits (282), Expect = 3e-24
Identities = 103/401 (25%), Positives = 182/401 (44%), Gaps = 75/401 (18%)
Query: 117 VRKDEKGLVLEITEKGEKLGERPI--DIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAR 174
+R+ + L + +K E+ E+ + +I +K L +KG V+ E+ R + K++
Sbjct: 1 MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVT--EVLRGMG-------KLSP 51
Query: 175 EDERVERTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIY 234
E+ V ++ ++ + K IE K E L + R+++ + ++ P + +
Sbjct: 52 EERPV--IGQLANDVREAIGKAIESKMEA------LEQAEIHRKLQEETIDVTLPGRPVL 103
Query: 235 PGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLK 294
G P + ++ I +GF + IET ++NF+AL P++HPAR+ D++
Sbjct: 104 KGGAHPLTATITEVEDLFIGLGF-SVAEGPQIETDYYNFEALNLPKDHPARDMQDSF--- 159
Query: 295 YPEKGYLPDESLV-SRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKG 353
Y DE L+ ++ R + +G G +
Sbjct: 160 -----YFTDELLLRTQTSPVQARTMEKYKGKGPI-------------------------K 189
Query: 354 IEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKK 413
I PGK VFR D D TH +F QI+G + L G+L+ FA G ++
Sbjct: 190 IICPGK------VFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEER 243
Query: 414 -VKFFPDYYPFTEPSVQLSA-----------YHPELGWVEFGGAGVFREEMTEALGI--- 458
++ P ++PFTEPSV++ + GW+E GAG+ + E G
Sbjct: 244 SIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPN 303
Query: 459 KVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLREAKLI 499
+ A+G+G++RL+M K GIDDIR+ ++ D R+L + K +
Sbjct: 304 EYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRV 344
>pir||C82225 phenylalanyl-tRNA synthetase, alpha chain VC1219 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9655700|gb|AAF94378.1| (AE004202) phenylalanyl-tRNA
synthetase, alpha chain [Vibrio cholerae]
Length = 327
Score = 111 bits (276), Expect = 1e-23
Identities = 96/363 (26%), Positives = 164/363 (44%), Gaps = 67/363 (18%)
Query: 141 DIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELK 200
++ ++ L +KGE++V ++ + + +RR +E + V+ +K + EL+
Sbjct: 26 EVRVQYLGKKGELTV-QLQSLGKLPPEERRTAGQEINVAKEAVQKALAERKDALQSAELE 84
Query: 201 REVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEM 260
++ T ++ P +RI G P +++I E+GF
Sbjct: 85 AKLAAET----------------IDVTLPGRRIENGGLHPVTRTIERIESFFGELGF--- 125
Query: 261 TVDS--LIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGL 318
TV+S IE F NFDAL +HPAR DT+
Sbjct: 126 TVESGPEIEDDFHNFDALNIAADHPARTDHDTF--------------------------- 158
Query: 319 AGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLI 378
++P+ LM R H + + R L + + P ++ RV+R D D+TH
Sbjct: 159 --------FFNPK----LMLRTHTSGVQIRTLEER-QPPLRFIAPGRVYRNDY-DQTHTP 204
Query: 379 EFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPEL 437
F+Q++G + E++ F L GIL F +V+F P Y+PFTEPS ++
Sbjct: 205 MFHQVEGMLVDENVNFAQLKGILHDFLCNFFEEDLEVRFRPSYFPFTEPSAEVDVKGKNG 264
Query: 438 GWVEFGGAGVFREEMTEALGI---KVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLR 494
W+E G G+ + ++GI K A+G+G++RL M + G++D+R F DLR+L+
Sbjct: 265 KWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLK 324
Query: 495 EAK 497
+ K
Sbjct: 325 QFK 327
>pir||D70620 probable pheS protein - Mycobacterium tuberculosis (strain H37RV)
>gi|1839001|emb|CAB06643.1| (Z85982) pheS [Mycobacterium
tuberculosis]
Length = 341
Score = 111 bits (274), Expect = 2e-23
Identities = 87/329 (26%), Positives = 143/329 (43%), Gaps = 46/329 (13%)
Query: 172 IAREDERVERTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVK 231
+AR+ V + E GK++ + +R L A + + ++ P
Sbjct: 43 LARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATLRAERDAAVLVAEGIDVTLPST 102
Query: 232 RIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTY 291
R+ G + P + + + I MG+ E+ +ET+ +NFDAL P +HPAR DT+
Sbjct: 103 RVPAGARHPIIMLAEHVADTFIAMGW-ELAEGPEVETEQFNFDALNFPADHPARGEQDTF 161
Query: 292 QLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLA 351
+ +PE + L+ R H + + R L
Sbjct: 162 YI-----------------------------------APEDSRQLL-RTHTSPVQIRTLL 185
Query: 352 KGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFA-IEIAG 410
E+P +I R FR D LD TH F+Q++G L+ HL G L FA E
Sbjct: 186 AR-ELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLRGTLDAFARAEFGP 244
Query: 411 AKKVKFFPDYYPFTEPSVQLSAYHPE----LGWVEFGGAGVFREEMTEALGIKVPV---I 463
+ + + P ++PFTEPS ++ + WVE+GG G+ + A GI +
Sbjct: 245 SARTRIRPHFFPFTEPSAEVDVWFANKIGGAAWVEWGGCGMVHPNVLRATGIDPDLYSGF 304
Query: 464 AWGIGIDRLAMFKLGIDDIRYLFSYDLRW 492
A+G+G++R F+ GI D+R + D+R+
Sbjct: 305 AFGMGLERTLQFRNGIPDMRDMVEGDVRF 333
>pir||H72329 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain - Thermotoga
maritima (strain MSB8)
>gi|4981352|gb|AAD35903.1|AE001749_6 (AE001749)
phenylalanyl-tRNA synthetase, alpha subunit [Thermotoga
maritima]
Length = 325
Score = 111 bits (274), Expect = 2e-23
Identities = 96/334 (28%), Positives = 154/334 (45%), Gaps = 56/334 (16%)
Query: 164 VKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKP 223
+K+LK +R E+ EK +KL E ++++ R+ + ++E
Sbjct: 41 MKNLKNLPPEERPAYGKRVNELREKIEKLFE---EKRQQIQRILEQ-------EKMEKMR 90
Query: 224 FNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHP 283
++ P R G P +++I R + MGF ++ IET + NFDAL P+ HP
Sbjct: 91 IDVTVPGARRKLGHSHPVLKVMEEIERIFVSMGF-DVVEGPEIETTWHNFDALNTPEWHP 149
Query: 284 AREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHAT 343
AR+ D++ Y+ D+ L+ H SP + ++ R
Sbjct: 150 ARDEHDSF--------YITDDLLL----RTHT-------------SPVQIRTMLERKPPI 184
Query: 344 ALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKR 403
A+ + PGK V+R D D THL F+Q++G DL+ HL L+
Sbjct: 185 AIIS---------PGK------VYRRD-YDATHLPMFHQVEGLHVDRDLSVAHLKFTLEE 228
Query: 404 FAIEIAG-AKKVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGI---K 459
FA + G KV+ P ++PFTEPS ++ Y GW+E GAG+ + +G +
Sbjct: 229 FARRMFGEGAKVRLRPSFFPFTEPSFEVDVYLSGYGWLEILGAGMVDPNVFLNVGYDPEE 288
Query: 460 VPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWL 493
A+G+G++R+AM K GI DIR D+R+L
Sbjct: 289 WTGYAFGMGVERIAMLKYGIADIREFVRNDVRFL 322
>sp|P17921|SYFA_BACSU PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7428485|pir||YFBSA
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Bacillus subtilis >gi|1770030|emb|CAA99603.1| (Z75208)
phenylalany-tRNA synthetase beta subunit [Bacillus
subtilis] >gi|2635329|emb|CAB14824.1| (Z99118)
phenylalanyl-tRNA synthetase (alpha subunit) [Bacillus
subtilis]
Length = 344
Score = 108 bits (267), Expect = 2e-22
Identities = 97/380 (25%), Positives = 173/380 (45%), Gaps = 68/380 (17%)
Query: 144 LKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREV 203
LK L ++ V+ S + V D++ + + ++ E + + + K L EV
Sbjct: 5 LKQLEQEALEQVEAASSLKVVNDIRVQYLGKKGPITEVLRGMGKLSAEERPKMGALANEV 64
Query: 204 TRLTPELIA--SGKWREVELKP------FNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEM 255
IA + K E E+K ++ P + G + P V +++I I M
Sbjct: 65 RERIANAIADKNEKLEEEEMKQKLAGQTIDVTLPGNPVAVGGRHPLTVVIEEIEDLFIGM 124
Query: 256 GFIEMTVDS--LIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLV-SRVKE 312
G+ TV+ +ET ++NF++L P+ HPAR+ D++ Y+ +E+L+ ++
Sbjct: 125 GY---TVEEGPEVETDYYNFESLNLPKEHPARDMQDSF--------YITEETLMRTQTSP 173
Query: 313 AHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVL 372
R + G G V I PGK V+R D
Sbjct: 174 VQTRTMEKHEGKGPV-------------------------KIICPGK------VYRRDND 202
Query: 373 DRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGA-KKVKFFPDYYPFTEPSVQLS 431
D TH +F QI+G V ++++ L G L+ A ++ G ++++ P ++PFTEPSV++
Sbjct: 203 DATHSHQFMQIEGLVVDKNISMSDLKGTLELVAKKMFGQDREIRLRPSFFPFTEPSVEVD 262
Query: 432 -----------AYHPELGWVEFGGAGVFREEMTEALGI---KVPVIAWGIGIDRLAMFKL 477
+ GW+E GAG+ + + G + A+G+G++R+AM K
Sbjct: 263 VTCFKCGGNGCSVCKGTGWIEILGAGMVHPNVLKMAGFDPKEYQGFAFGMGVERIAMLKY 322
Query: 478 GIDDIRYLFSYDLRWLREAK 497
GIDDIR+ ++ D+R++ + K
Sbjct: 323 GIDDIRHFYTNDVRFISQFK 342
>sp|Q55187|SYFA_SYNY3 PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7437774|pir||S74410
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Synechocystis sp. (strain PCC 6803)
>gi|1001185|dbj|BAA10328.1| (D64001) phenylalanyl-tRNA
synthetase alpha chain [Synechocystis sp.]
Length = 331
Score = 105 bits (260), Expect = 1e-21
Identities = 77/264 (29%), Positives = 124/264 (46%), Gaps = 46/264 (17%)
Query: 236 GKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKY 295
G++ P +D++ + +G+ T +ET ++NF+AL P +HPAR+ DT+ LK
Sbjct: 109 GRRHPLNSTVDRVLDIFVGLGYTVATGPQ-VETDYYNFEALNIPADHPARDMQDTFFLK- 166
Query: 296 PEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIE 355
D L+ R H + + R + K +
Sbjct: 167 -------DGRLL-------------------------------RTHTSPVQIRYMEKH-D 187
Query: 356 IPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAG-AKKV 414
P + RV+R D +D TH F+Q++ + L F HL G ++ F ++ G A +
Sbjct: 188 PPIRIVAPGRVYRRDTVDATHSAVFHQVELLAIDKGLAFTHLKGTIQAFIKQMFGEALPI 247
Query: 415 KFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPV---IAWGIGIDR 471
+F Y+PFTEPS ++ + W+E G G+ + EA+G V A G G++R
Sbjct: 248 RFRASYFPFTEPSAEVDVQW-QGKWLEVMGCGMVDPNVMEAVGYDPEVYTGFAAGFGVER 306
Query: 472 LAMFKLGIDDIRYLFSYDLRWLRE 495
AM IDDIR L++ DLR+LR+
Sbjct: 307 FAMVLHQIDDIRRLYNSDLRFLRQ 330
>pir||T36830 probable phenylalanyl-tRNA synthetase alpha chain - Streptomyces
coelicolor >gi|3581850|emb|CAA20806.1| (AL031541)
putative phenylalanyl-tRNA synthetase alpha chain
[Streptomyces coelicolor A3(2)]
Length = 373
Score = 105 bits (260), Expect = 1e-21
Identities = 88/330 (26%), Positives = 143/330 (42%), Gaps = 56/330 (16%)
Query: 187 EKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLD 246
E GK++ + + + EL A R + + ++ P R+ G + P +
Sbjct: 72 EAGKRVGMARGAVNKALAARQEELEAERDARVLVEEAVDVTLPHDRVPAGARHPLTTLSE 131
Query: 247 KIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESL 306
+I + MG+ E+ E +++NFDAL +HPAR DT+ ++ PE G
Sbjct: 132 RIEDIFVAMGY-EVAEGPEAEAEWFNFDALNIGPDHPARGEADTFFVQGPEGG------- 183
Query: 307 VSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRV 366
E ++L R H + + R A E+P RV
Sbjct: 184 -----------------------AESGVVL--RTHTSPVQIRS-ALTRELPVYVICPGRV 217
Query: 367 FRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTE 425
+R D LD TH F+Q++ E LT L G L + GA+ K + P+++PFTE
Sbjct: 218 YRTDELDATHTPVFHQVELLAVDEGLTMADLKGTLDHMVQSLFGAEMKTRLRPNFFPFTE 277
Query: 426 PSVQL----------SAYHPEL--------GWVEFGGAGVFREEMTEALGI---KVPVIA 464
PS ++ S +P+ GW+E GG G+ + A GI K A
Sbjct: 278 PSAEMDMLCYVCKGASVGNPDRPCRTCSSEGWIELGGCGMVNPRVLTACGIDPEKYSGFA 337
Query: 465 WGIGIDRLAMFKLGIDDIRYLFSYDLRWLR 494
+G GI+R+ MF+ ++D+R + D+R+ R
Sbjct: 338 FGFGIERMLMFRHNVEDMRDMVEGDVRFTR 367
>emb|CAA37224.1| (X53057) phenylalanyl-tRNA synthetase alpha subunit [Bacillus
subtilis]
Length = 343
Score = 103 bits (254), Expect = 5e-21
Identities = 77/278 (27%), Positives = 135/278 (47%), Gaps = 60/278 (21%)
Query: 238 KQPYRVFLDKIRRRLIEMGFIEMTVDS--LIETQFWNFDALFQPQNHPAREWTDTYQLKY 295
+ P V +++I I MG+ TV+ +ET ++NF++L P+ HPAR+ D++
Sbjct: 106 RHPLTVVIEEIEDLFIGMGY---TVEEGPEVETDYYNFESLNLPKEHPARDMQDSF---- 158
Query: 296 PEKGYLPDESLV-SRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGI 354
Y+ +E+L+ ++ R + G G V I
Sbjct: 159 ----YITEETLMRTQTSPVQTRTMEKHEGKGPV-------------------------KI 189
Query: 355 EIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGA-KK 413
PGK V+R D D TH +F QI+G V ++++ L G L+ A ++ G ++
Sbjct: 190 ICPGK------VYRRDNDDATHSHQFMQIEGLVVDKNISMSDLKGTLELVAKKMFGQDRE 243
Query: 414 VKFFPDYYPFTEPSVQLS-----------AYHPELGWVEFGGAGVFREEMTEALGI---K 459
++ P ++PFTEPSV++ + GW+E GAG+ + + G +
Sbjct: 244 IRLRPSFFPFTEPSVEVDVTCFKCGGNGCSVCKGTGWIEILGAGMVHPNVLKMAGFDPKE 303
Query: 460 VPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLREAK 497
A+G+G++R+AM K GIDDIR+ ++ D+R++ + K
Sbjct: 304 YQGFAFGMGVERIAMLKYGIDDIRHFYTNDVRFISQFK 341
>sp|O67087|SYFA_AQUAE PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7437770|pir||D70382
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Aquifex aeolicus >gi|2983471|gb|AAC07051.1| (AE000715)
phenylalanyl-tRNA synthetase alpha subunit [Aquifex
aeolicus]
Length = 338
Score = 102 bits (251), Expect = 1e-20
Identities = 96/375 (25%), Positives = 168/375 (44%), Gaps = 65/375 (17%)
Query: 144 LKLLSEKGEVSVDEISRIIDVKDLKRRKIARED---ERVERTVEITEKGKKLVSKGIEL- 199
L + E+ ++ + +S + ++++++ + + + E +++ E+ + +K K + L
Sbjct: 4 LDKILEELKLLLSSVSSLKELQEVRSKFLGSKGVIKELLKKIKEVPSEERKEYGKRVNLL 63
Query: 200 KREVTRLTPELIASGKWREVELKP----FNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEM 255
K E +L E K RE+E K ++ P R G P V L++I M
Sbjct: 64 KEEAEKLIKEKEEELKERELEEKLKGEWVDLSIPPARTV-GSLHPITVTLERIVTIFRGM 122
Query: 256 GFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHE 315
GF E+ +E + +NFD L P+ HPAR+ DT+ + +GYL
Sbjct: 123 GF-EVEEGPEVEREEYNFDMLNIPKEHPARDMQDTFYVN--REGYLL------------- 166
Query: 316 RGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRT 375
R H + + R + K + P + +V+R D D T
Sbjct: 167 -----------------------RTHTSPVQIRTMLKK-KPPIQIIAPGKVYRRDD-DPT 201
Query: 376 HLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLSA-- 432
H F+Q++G V E FRH+ +++ F + V+F Y+PFTEPS ++
Sbjct: 202 HSPMFHQVEGLVVNEYANFRHMKYVIEEFLKKFFETDLPVRFRTSYFPFTEPSAEVDIGC 261
Query: 433 --YHPE-------LGWVEFGGAGVFREEMTEALGIKVPV---IAWGIGIDRLAMFKLGID 480
H E GW+E G G+ ++ E GI A+G+G++RLAM GID
Sbjct: 262 VICHQEGCRVCKHTGWLEVMGCGMVHPKVLENCGIDTDFYQGFAFGMGVERLAMLLFGID 321
Query: 481 DIRYLFSYDLRWLRE 495
+I+ + DLR++++
Sbjct: 322 NIKLFYENDLRFIKQ 336
>sp|P57229|SYFA_BUCAI PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|10038812|dbj|BAB12847.1|
(AP001118) phenylalanyl-tRNA synthetase alpha chain
[Buchnera sp. APS]
Length = 329
Score = 101 bits (250), Expect = 2e-20
Identities = 90/377 (23%), Positives = 174/377 (45%), Gaps = 63/377 (16%)
Query: 125 VLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVE 184
++EI + K I +K L +KG ++ +K+ K +++ + ++
Sbjct: 10 IIEIDIQNSKKISELDKIRIKYLGKKGVLTAF----------MKKLKDFSYEDKKKHSII 59
Query: 185 ITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVF 244
I +K ++++SK I +K++ +L+ ++ + ++ + +I P +R G P
Sbjct: 60 INKKKQEIISK-INIKKQ--KLSVYILE----QRIKSETIDISLPGRRTEHGGFHPITNT 112
Query: 245 LDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDE 304
+D I+ +++GF + IE ++ NFDAL + HPAR+ DT+
Sbjct: 113 IDYIKNFFLKLGFQSINSPE-IEDEYHNFDALNISKYHPARDSHDTF------------- 158
Query: 305 SLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQ 364
W +L R +++ R + K + P ++
Sbjct: 159 -----------------------WFDRNRLL---RTQTSSMQIR-IMKQEKPPIRFIFPG 191
Query: 365 RVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKK-VKFFPDYYPF 423
+V+R D D TH F+QI+G + +++ F +L I+ +F + G + +KF P Y+PF
Sbjct: 192 KVYRNDY-DITHTPMFHQIEGLIVDKNINFSNLKWIIYKFLYDFFGKEVLIKFRPSYFPF 250
Query: 424 TEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVI---AWGIGIDRLAMFKLGID 480
T PS ++ +E G G+ + + + I + A+G+GI+R+AM + GI
Sbjct: 251 TVPSAEVDIIDHNGKSLEILGCGMVHPNVLKNVNIDSKIYSACAFGLGIERIAMLRYGIT 310
Query: 481 DIRYLFSYDLRWLREAK 497
DIR F D+R+L++ K
Sbjct: 311 DIRSFFENDIRFLKQFK 327
>sp|Q9ZDB5|SYFA_RICPR PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7437771|pir||H71699
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Rickettsia prowazekii >gi|3860974|emb|CAA14874.1|
(AJ235271) PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN
(pheS) [Rickettsia prowazekii]
Length = 350
Score = 100 bits (247), Expect = 4e-20
Identities = 99/379 (26%), Positives = 167/379 (43%), Gaps = 74/379 (19%)
Query: 140 IDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVS----- 194
I+ LKL EK I + ++KDL+ K+ E + R +T + KKL S
Sbjct: 4 IETILKLAEEK-------IVLVHNLKDLQEYKV----EFLGRNGIVTSELKKLGSLINGQ 52
Query: 195 KGIELKREVTRLTPEL--IASGKWREVELKPFNIKA---------PVKRIYPGKKQPYRV 243
K E ++ L ++ I K + +E + ++K P +R G P
Sbjct: 53 KRKEFGLKINTLKDKIHDIIKAKAQNLEAEELHLKLAADKIDLTIPARRYKQGSIHPITQ 112
Query: 244 FLDKIRRRLIEMGFIEMTVDS--LIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYL 301
+D++ + + GF T+++ IE F+NF AL +HPAR+ DT+ LK
Sbjct: 113 CMDELIQVFSQFGF---TIENGPNIENDFYNFTALNFEYDHPARQMHDTFYLK------- 162
Query: 302 PDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYF 361
HE ++ +LL R H + + R + G + P ++
Sbjct: 163 -----------GHEN--------------DKPLLL--RTHTSTVQIRAMKNG-KPPFRFI 194
Query: 362 TIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKV--KFFPD 419
R +R D D TH F+QI+G V +++ HL ++ F + +F P
Sbjct: 195 APGRTYRSDS-DMTHTPMFHQIEGLVIDKNINMGHLKYVIITFIRSFFENSNIELRFRPS 253
Query: 420 YYPFTEPSVQLSA-YHPELGWVEFGGAGVFREEMTEALGI---KVPVIAWGIGIDRLAMF 475
++PFTEPS ++ + W+E G G+ + + + I + A+G+G++R AM
Sbjct: 254 FFPFTEPSAEVDIRMNKNDKWLEVLGCGMVHPNVLKNIDINRSEYQGFAFGLGVERFAML 313
Query: 476 KLGIDDIRYLFSYDLRWLR 494
K I D+R F D+RWL+
Sbjct: 314 KYNIKDLRRFFEGDIRWLK 332
>emb|CAA23564.1| (V00291) phenylalanyl-tRNA synthetase beta-subunit (pheS; EC
6.1.1.20) [Escherichia coli]
Length = 331
Score = 100 bits (246), Expect = 5e-20
Identities = 79/304 (25%), Positives = 133/304 (42%), Gaps = 46/304 (15%)
Query: 198 ELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGF 257
++++ + EL ++ + + ++ P +RI G P +D+I E+GF
Sbjct: 70 QVQQALNAAKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGF 129
Query: 258 IEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERG 317
T IE + NFDAL P +HPAR DT+
Sbjct: 130 TVATGPE-IEDDYHNFDALNIPGHHPARADHDTF-------------------------- 162
Query: 318 LAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHL 377
W +L R + + R + K + P + RV+R D D+TH
Sbjct: 163 ----------WFDTTRLL---RTQTSGVQIRTM-KAQQPPIRIIAPGRVYRNDY-DQTHT 207
Query: 378 IEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPE 436
F+Q++G + +++F +L G L F +++F P Y+PFTEPS ++
Sbjct: 208 PMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKN 267
Query: 437 LGWVEFGGAGVFREEMTEALGIKVPV---IAWGIGIDRLAMFKLGIDDIRYLFSYDLRWL 493
W+E G G+ + +GI V A+G+G++RL M + G+ D+R F DLR+L
Sbjct: 268 GKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFL 327
Query: 494 REAK 497
++ K
Sbjct: 328 KQFK 331
>gb|AAA51469.1| (K02844) phenylalanyl-tRNA synthetase alpha-subunit [Escherichia
coli]
Length = 327
Score = 100 bits (246), Expect = 5e-20
Identities = 79/304 (25%), Positives = 133/304 (42%), Gaps = 46/304 (15%)
Query: 198 ELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGF 257
++++ + EL ++ + + ++ P +RI G P +D+I E+GF
Sbjct: 66 QVQQALNAAKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGF 125
Query: 258 IEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERG 317
T IE + NFDAL P +HPAR DT+
Sbjct: 126 TVATGPE-IEDDYHNFDALNIPGHHPARADHDTF-------------------------- 158
Query: 318 LAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHL 377
W +L R + + R + K + P + RV+R D D+TH
Sbjct: 159 ----------WFDTTRLL---RTQTSGVQIRTM-KAQQPPIRIIAPGRVYRNDY-DQTHT 203
Query: 378 IEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPE 436
F+Q++G + +++F +L G L F +++F P Y+PFTEPS ++
Sbjct: 204 PMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKN 263
Query: 437 LGWVEFGGAGVFREEMTEALGIKVPV---IAWGIGIDRLAMFKLGIDDIRYLFSYDLRWL 493
W+E G G+ + +GI V A+G+G++RL M + G+ D+R F DLR+L
Sbjct: 264 GKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFL 323
Query: 494 REAK 497
++ K
Sbjct: 324 KQFK 327
>sp|P08312|SYFA_ECOLI PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7428484|pir||SYECFA
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Escherichia coli >gi|1788007|gb|AAC74784.1| (AE000266)
phenylalanine tRNA synthetase, alpha-subunit
[Escherichia coli K12]
Length = 327
Score = 99.8 bits (245), Expect = 6e-20
Identities = 77/277 (27%), Positives = 122/277 (43%), Gaps = 46/277 (16%)
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
++ P +RI G P +D+I E+GF T IE + NFDAL P +HPA
Sbjct: 93 DVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPE-IEDDYHNFDALNIPGHHPA 151
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATA 344
R DT+ W +L R +
Sbjct: 152 RADHDTF------------------------------------WFDTTRLL---RTQTSG 172
Query: 345 LSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRF 404
+ R + K + P + RV+R D D+TH F+Q++G + +++F +L G L F
Sbjct: 173 VQIRTM-KAQQPPIRIIAPGRVYRNDY-DQTHTPMFHQMEGLIVDTNISFTNLKGTLHDF 230
Query: 405 AIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPV- 462
+++F P Y+PFTEPS ++ W+E G G+ + +GI V
Sbjct: 231 LRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVY 290
Query: 463 --IAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLREAK 497
A+G+G++RL M + G+ D+R F DLR+L++ K
Sbjct: 291 SGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK 327
>dbj|BAA15482.1| (D90813) Phenylalanine--tRNA ligase (EC 6.1.1.20) a chain
[Escherichia coli] >gi|1742807|dbj|BAA15494.1| (D90814)
Phenylalanine--tRNA ligase (EC 6.1.1.20) a chain
[Escherichia coli]
Length = 331
Score = 99.8 bits (245), Expect = 6e-20
Identities = 77/277 (27%), Positives = 122/277 (43%), Gaps = 46/277 (16%)
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
++ P +RI G P +D+I E+GF T IE + NFDAL P +HPA
Sbjct: 97 DVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPE-IEDDYHNFDALNIPGHHPA 155
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATA 344
R DT+ W +L R +
Sbjct: 156 RADHDTF------------------------------------WFDTTRLL---RTQTSG 176
Query: 345 LSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRF 404
+ R + K + P + RV+R D D+TH F+Q++G + +++F +L G L F
Sbjct: 177 VQIRTM-KAQQPPIRIIAPGRVYRNDY-DQTHTPMFHQMEGLIVDTNISFTNLKGTLHDF 234
Query: 405 AIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPV- 462
+++F P Y+PFTEPS ++ W+E G G+ + +GI V
Sbjct: 235 LRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVY 294
Query: 463 --IAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLREAK 497
A+G+G++RL M + G+ D+R F DLR+L++ K
Sbjct: 295 SGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK 331
>sp|Q9ZKF9|SYFA_HELPJ PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7437775|pir||E71863
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Helicobacter pylori (strain J99)
>gi|4155565|gb|AAD06559.1| (AE001527) PHENYLALANYL-TRNA
SYNTHETASE ALPHA CHAIN [Helicobacter pylori J99]
Length = 328
Score = 98.7 bits (242), Expect = 1e-19
Identities = 94/364 (25%), Positives = 153/364 (41%), Gaps = 74/364 (20%)
Query: 144 LKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREV 203
L L +KG V D+ +++ ++ ++ A+E ++ E K ELK++
Sbjct: 22 LNALGKKG-VFADKFNQLKNLNGEEKNAFAKEIHHYKQAFE----------KAFELKKKA 70
Query: 204 TRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVD 263
+ EL K ++++ FN I P +KI +G+ ++ +
Sbjct: 71 I-MELELEERLKKEKIDVSLFNA------IKTSSSHPLNYTKNKIIEFFTPLGY-KLEIG 122
Query: 264 SLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRG 323
SL+E F NF AL P HPAR+ DT+ Y D L+
Sbjct: 123 SLVEDDFHNFSALNLPPYHPARDMQDTF--------YFKDHKLL---------------- 158
Query: 324 WGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQI 383
R H + + + + P K + FR D D TH F+QI
Sbjct: 159 ---------------RTHTSPVQIHTMQEQTP-PIKMICLGETFRCDY-DLTHTPMFHQI 201
Query: 384 DGFVAGE--DLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLS---------- 431
+G V + ++ F HL G+++ F G K+++ ++PFTEPS ++
Sbjct: 202 EGLVVDQKGNIRFTHLKGVIEDFLHYFFGGVKLRWRSSFFPFTEPSAEVDISCVFCKQEG 261
Query: 432 -AYHPELGWVEFGGAGVFREEMTEALGIK-VPVIAWGIGIDRLAMFKLGIDDIRYLFSYD 489
GW+E G G+ + EA+G + V A+G+GI+RLAM I+D+R F D
Sbjct: 262 CRVCSHTGWLEVLGCGMVNNAVFEAIGYENVSGFAFGMGIERLAMLTCQINDLRSFFETD 321
Query: 490 LRWL 493
LR L
Sbjct: 322 LRVL 325
>gb|AAB61946.1| (U01668) phenylalanyl-tRNA synthetase alpha subunit (Gly294
variant) [unidentified cloning vector]
Length = 327
Score = 98.3 bits (241), Expect = 2e-19
Identities = 76/277 (27%), Positives = 121/277 (43%), Gaps = 46/277 (16%)
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
++ P +RI G P +D+I E+GF T IE + NFDAL P +HPA
Sbjct: 93 DVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPE-IEDDYHNFDALNIPGHHPA 151
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATA 344
R DT+ W +L R +
Sbjct: 152 RADHDTF------------------------------------WFDTTRLL---RTQTSG 172
Query: 345 LSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRF 404
+ R + K + P + RV+R D D+TH F+Q++G + +++F +L G L F
Sbjct: 173 VQIRTM-KAQQPPIRIIAPGRVYRNDY-DQTHTPMFHQMEGLIVDTNISFTNLKGTLHDF 230
Query: 405 AIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPV- 462
+++F P Y+PFTEPS ++ W+E G G+ + +GI V
Sbjct: 231 LRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVY 290
Query: 463 --IAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLREAK 497
+G+G++RL M + G+ D+R F DLR+L++ K
Sbjct: 291 SGFGFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK 327
>sp|P56146|SYFA_HELPY PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|7437772|pir||C64570
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Helicobacter pylori (strain 26695)
>gi|2313509|gb|AAD07472.1| (AE000556) phenylalanyl-tRNA
synthetase, alpha subunit (pheS) [Helicobacter pylori
26695]
Length = 328
Score = 97.9 bits (240), Expect = 2e-19
Identities = 92/364 (25%), Positives = 151/364 (41%), Gaps = 74/364 (20%)
Query: 144 LKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREV 203
L L +KG V D+ +++ + ++ A+E ++ E + KK +EL+ +
Sbjct: 22 LNALGKKG-VFADKFNQLKHLNGEEKNAFAKEIHHYKQAFEKAFEWKKKAIIELELEERL 80
Query: 204 TRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVD 263
K ++++ FN I P +KI +G+ ++ +
Sbjct: 81 -----------KKEKIDVSLFNA------IKTSSSHPLNYTKNKIIEFFTPLGY-KLEIG 122
Query: 264 SLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRG 323
SL+E F NF AL P HPAR+ DT+ Y D L+
Sbjct: 123 SLVEDDFHNFSALNLPPYHPARDMQDTF--------YFKDHKLL---------------- 158
Query: 324 WGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQI 383
R H + + + + P K + FR D D TH F+QI
Sbjct: 159 ---------------RTHTSPVQIHTMQEQTP-PIKMICLGETFRRDY-DLTHTPMFHQI 201
Query: 384 DGFVAGE--DLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLS---------- 431
+G V + ++ F HL G+++ F G K+++ ++PFTEPS ++
Sbjct: 202 EGLVVDQKGNIRFTHLKGVIEDFLHYFFGGVKLRWRSSFFPFTEPSAEVDISCVFCKQEG 261
Query: 432 -AYHPELGWVEFGGAGVFREEMTEALGIK-VPVIAWGIGIDRLAMFKLGIDDIRYLFSYD 489
GW+E G G+ + EA+G + V A+G+GI+RLAM I+D+R F D
Sbjct: 262 CRVCSHTGWLEVLGCGMVNNAVFEAIGYENVSGFAFGMGIERLAMLTCQINDLRSFFETD 321
Query: 490 LRWL 493
LR L
Sbjct: 322 LRVL 325
>sp|P43819|SYFA_HAEIN PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|1075133|pir||H64115
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Haemophilus influenzae >gi|1574769|gb|AAC22957.1|
(U32810) phenylalanyl-tRNA synthetase, alpha subunit
(pheS) [Haemophilus influenzae Rd]
Length = 329
Score = 96.3 bits (236), Expect = 7e-19
Identities = 76/293 (25%), Positives = 131/293 (43%), Gaps = 52/293 (17%)
Query: 215 KWREVELKP------FNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIET 268
+W + EL ++ P +++ G P + ++++ + E+GF + IE+
Sbjct: 79 EWEQAELNSKLEKERVDVSLPGRKVETGGLHPVTMTINRVTKFFSELGF-SVENGPEIES 137
Query: 269 QFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVW 328
++NFDAL P++HPAR DT+ W +
Sbjct: 138 DYYNFDALNIPKHHPARADHDTF--------------------------------W---F 162
Query: 329 SPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVA 388
+PE L+ R + + R + K ++ P + RV+R D D+TH F+QI+
Sbjct: 163 NPE----LLLRTQTSGVQIRTMEK-MQPPIRIMAPGRVYRNDY-DQTHTPMFHQIELLYV 216
Query: 389 GEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGV 447
+ F L G+L F +V+F P Y+PFTEPS ++ W+E G G+
Sbjct: 217 DKKANFTELKGLLHDFLRAFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGM 276
Query: 448 FREEMTEALGI---KVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLREAK 497
+ +GI + A G+G++RL M + + D+R F DLR+L++ K
Sbjct: 277 VHPNVLRNVGIDPNEYSGFAVGMGVERLTMLRYNVTDLRSFFENDLRFLKQFK 329
>pir||F81939 probable phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain
NMA0933 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|6900402|emb|CAB72013.1| (AJ391257)
phenylalanine-tRNA-synthetase alpha chain [Neisseria
meningitidis] >gi|7379638|emb|CAB84205.1| (AL162754)
putative phenylalanyl-tRNA synthetase alpha chain
[Neisseria meningitidis Z2491]
Length = 330
Score = 96.3 bits (236), Expect = 7e-19
Identities = 77/276 (27%), Positives = 114/276 (40%), Gaps = 46/276 (16%)
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
+I P + G P + L ++ MGF E+ IE F NF AL P NHPA
Sbjct: 93 DITLPGRAQEGGSLHPVTLTLQRVVELFHGMGF-EVADGPEIEDDFHNFQALNIPANHPA 151
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATA 344
R DT+ Y E G + R H +
Sbjct: 152 RAMQDTF---YVENGDVL------------------------------------RTHTSP 172
Query: 345 LSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRF 404
+ R + E P + RV+R D D TH F+Q +G E +TF L + F
Sbjct: 173 IQIRYMLDKKEPPVRIIAPGRVYRVDS-DATHSPMFHQAEGLWVEEGVTFADLKAVFTDF 231
Query: 405 AIEIAGAK--KVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGI---K 459
+V+F P ++PFTEPS ++ W+E GG G+ + + + I K
Sbjct: 232 IRRFFERDDLQVRFRPSFFPFTEPSAEIDIMGENGKWLEVGGCGMVHPNVLKNVNIDPEK 291
Query: 460 VPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLRE 495
A+GIG+DR AM + ++D+R F DL +L++
Sbjct: 292 YTGFAFGIGLDRFAMLRYNVNDLRLFFDNDLNFLKQ 327
>pir||H75283 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain - Deinococcus
radiodurans (strain R1)
>gi|6460167|gb|AAF11900.1|AE002066_4 (AE002066)
phenylalanyl-tRNA synthetase, alpha subunit [Deinococcus
radiodurans]
Length = 339
Score = 96.0 bits (235), Expect = 9e-19
Identities = 73/244 (29%), Positives = 109/244 (43%), Gaps = 59/244 (24%)
Query: 266 IETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWG 325
+E + +NF+AL P HPAR+ DT+
Sbjct: 127 VEEEHYNFEALNVPWYHPARDLQDTF---------------------------------- 152
Query: 326 YVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDG 385
W + +L R H + + R + E P K +V+R + D TH F+Q++G
Sbjct: 153 --WLEDGRLL---RTHTSPMQIRYMVDH-EPPFKIVVRGKVYRYEATDATHEAMFHQLEG 206
Query: 386 FVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLSAY----HPELGWV 440
V G+ ++ L G + A + GA K +F P YYPF EP + Y E W+
Sbjct: 207 LVVGDGISMSDLKGTIAEMARGLYGASAKARFQPSYYPFVEPGADFAVYWENPRGESKWL 266
Query: 441 EFGGAG-----VFR--EEMTEALGIKVPV------IAWGIGIDRLAMFKLGIDDIRYLFS 487
E GG G VF+ +++ EA G K V A+G+G++R+AM K GI DIRY ++
Sbjct: 267 ELGGCGMVHPNVFKAVDDLREAAG-KDRVYEGKTGFAFGLGLERIAMLKYGIPDIRYFYA 325
Query: 488 YDLR 491
D R
Sbjct: 326 NDPR 329
>pir||G81165 phenylalanyl-tRNA synthetase, alpha chain NMB0724 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7225951|gb|AAF41137.1| (AE002427) phenylalanyl-tRNA
synthetase, alpha chain [Neisseria meningitidis MC58]
Length = 330
Score = 96.0 bits (235), Expect = 9e-19
Identities = 77/276 (27%), Positives = 114/276 (40%), Gaps = 46/276 (16%)
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
+I P + G P + L ++ MGF E+ IE F NF AL P NHPA
Sbjct: 93 DITLPGRAQEGGSLHPVTLTLQRVVELFHGMGF-EVADGPEIEDDFHNFQALNIPANHPA 151
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATA 344
R DT+ Y E G + R H +
Sbjct: 152 RAMQDTF---YVENGDVL------------------------------------RTHTSP 172
Query: 345 LSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRF 404
+ R + E P + RV+R D D TH F+Q +G E +TF L + F
Sbjct: 173 IQIRYMLDKKEPPIRIIAPGRVYRVDS-DATHSPMFHQAEGLWVEEGVTFADLKAVFTDF 231
Query: 405 AIEIAGAK--KVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGI---K 459
+V+F P ++PFTEPS ++ W+E GG G+ + + + I K
Sbjct: 232 IRRFFERDDLQVRFRPSFFPFTEPSAEIDIMGENGKWLEVGGCGMVHPNVLKNVNIDPEK 291
Query: 460 VPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLRE 495
A+GIG+DR AM + ++D+R F DL +L++
Sbjct: 292 YTGFAFGIGLDRFAMLRYNVNDLRLFFDNDLNFLKQ 327
>pir||B82767 phenylalanyl-tRNA synthetase alpha chain XF0741 [imported] -
Xylella fastidiosa (strain 9a5c)
>gi|9105631|gb|AAF83551.1|AE003916_5 (AE003916)
phenylalanyl-tRNA synthetase alpha chain [Xylella
fastidiosa]
Length = 333
Score = 92.1 bits (225), Expect = 1e-17
Identities = 74/279 (26%), Positives = 121/279 (42%), Gaps = 50/279 (17%)
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
++ P +R G P L++I +G+ E+ IE + NF+AL P +HPA
Sbjct: 95 DVTLPGRRGERGGLHPVTRTLERITEIFARLGY-ELVEGPEIEDDWHNFEALNFPLHHPA 153
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATA 344
R DT+ Y D L+ R H +
Sbjct: 154 RAMHDTF--------YFGDGRLL-------------------------------RTHTSG 174
Query: 345 LSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRF 404
+ R ++ P + +V+R D D+TH F+QI+G + + TF HL G L F
Sbjct: 175 VQVRYMSDH-RPPLRMIAAGKVYRSDS-DQTHSPMFHQIEGLLIDKHATFVHLKGTLSEF 232
Query: 405 AIEIAGAK-KVKFFPDYYPFTEPSVQLSAYHPE----LGWVEFGGAGVFREEMTEALGIK 459
+V+F P Y+PF EP ++ + + W+E G G+ + + +GI
Sbjct: 233 LRAFFERDFEVRFRPSYFPFVEPGAEVDIAWQQSDSSVRWLEVLGCGMVHPNVLKNVGID 292
Query: 460 VPV---IAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLRE 495
A+G+G++R AM + G+DD+R F D+R+LR+
Sbjct: 293 SECYTGFAFGLGVERFAMLRYGVDDLRAFFENDVRFLRQ 331
>pir||A81363 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain Cj0897c
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968335|emb|CAB73155.1| (AL139076) phenylalanyl-tRNA
synthetase alpha chain [Campylobacter jejuni]
Length = 330
Score = 91.7 bits (224), Expect = 2e-17
Identities = 81/277 (29%), Positives = 121/277 (43%), Gaps = 56/277 (20%)
Query: 233 IYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQ 292
I G P +DKI I + F + LIE F NF+AL P++HPAR+ DT+
Sbjct: 94 ITTGALHPVMSTMDKIIEYFIALNF-SIEKGPLIEDDFHNFEALNLPKSHPARDMQDTF- 151
Query: 293 LKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAK 352
Y D+ L+ SP + ++ A R +A
Sbjct: 152 -------YFDDKRLLRTQT-----------------SPVQIRTML----AQKPPIRMIAP 183
Query: 353 GIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVA--GEDLTFRHLLGILKRFAIEIAG 410
G VFR D D TH F+Q++G V G+ ++F +L +L+ F + G
Sbjct: 184 GA-----------VFRRD-FDITHTPMFHQVEGLVVEEGQKVSFANLKSVLEDFLRYMFG 231
Query: 411 AKKVKFFPDYYPFTEPSVQLS-----------AYHPELGWVEFGGAGVFREEMTEALGIK 459
KV+F P ++PFTEPS ++ GW+E G G+ + +G +
Sbjct: 232 DVKVRFRPSFFPFTEPSAEVDISCVFCKGKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYE 291
Query: 460 -VPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLRE 495
V A+G+G++R AM I D+R LF DLR L +
Sbjct: 292 NVSGYAFGLGVERFAMLLHQIPDLRSLFEGDLRLLEQ 328
>pir||C82888 phenylalanine-tRNA synthetase alpha chain UU458 [imported] -
Ureaplasma urealyticum
>gi|6899451|gb|AAF30870.1|AE002142_4 (AE002142)
phenylalanine-tRNA synthetase alpha chain [Ureaplasma
urealyticum]
Length = 333
Score = 87.0 bits (212), Expect = 4e-16
Identities = 81/317 (25%), Positives = 137/317 (42%), Gaps = 61/317 (19%)
Query: 200 KREVTRLTPELIA--SGKWREVELKPFNIK---APVKRIYPGKKQPYRVFLDKIRRRLIE 254
K+++ +T +++ + K +V+LK + K AP I G +D I +
Sbjct: 59 KQQIEFVTDQILKELNDKDDQVDLKKWTNKTLFAPF--INNGHHHILNSIIDDIASFFKK 116
Query: 255 MGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAH 314
+ F E+ S + + +NFD L +NHPAR D++ ++ +K
Sbjct: 117 LNF-EIVSGSEVVSPIYNFDHLNIDENHPARASADSF--------------FINSIK--- 158
Query: 315 ERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDR 374
M R H T +A+ L + + + V+R D D
Sbjct: 159 ----------------------MLRTHCTTTTAQFLENNVNKDIRIMSFGNVYRKDDDDA 196
Query: 375 THLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLS-- 431
TH +FNQ+D E LT +L ++ + G K ++ ++PFTEPS ++
Sbjct: 197 THSHQFNQVDFVWVKEGLTVANLKWLIDSLIKYLFGQNLKTRYRLSFFPFTEPSFEVDVQ 256
Query: 432 ---------AYHPELGWVEFGGAGVFREEMTEALGIKV--PVIAWGIGIDRLAMFKLGID 480
A + W+E G G+ E + +A I +A+G+GIDR+AM K ID
Sbjct: 257 CFKCDLKGCAVCKKSTWIEIMGTGMLHENVLKAANINDIRTGMAFGVGIDRIAMLKYEID 316
Query: 481 DIRYLFSYDLRWLREAK 497
DIRYL+S + ++ + K
Sbjct: 317 DIRYLYSNNFKFNAQIK 333
>pir||D71465 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain - Chlamydia
trachomatis (serotype D, strain UW3/Cx)
>gi|3329307|gb|AAC68433.1| (AE001356) Phenylalanyl tRNA
Synthetase, Alpha [Chlamydia trachomatis]
Length = 342
Score = 84.3 bits (205), Expect = 3e-15
Identities = 75/279 (26%), Positives = 120/279 (42%), Gaps = 65/279 (23%)
Query: 236 GKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKY 295
G K + LD + + GF + IE++ NF L ++HPAR+ DT+
Sbjct: 108 GGKHVIKKVLDDVVDIFVRFGFCVREAPN-IESEKNNFSLLNFEEDHPARQMQDTF---- 162
Query: 296 PEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKG-- 353
YL +++ R H + + +R+LA+
Sbjct: 163 ----YLDPTTVL-------------------------------RTHTSNVQSRELARNKP 187
Query: 354 ---IEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAG 410
I PG+ F + DV R+H+I F+Q++ F +D++F L +L F G
Sbjct: 188 PVRIVAPGECFRNE-----DVSARSHVI-FHQVEAFCVDKDISFSDLTSMLAGFYHIFFG 241
Query: 411 AK-KVKFFPDYYPFTEPSVQLS----------AYHPELGWVEFGGAGVFREEMTEALGI- 458
K +++F Y+PF EP +++ + GW+E GAG+ + I
Sbjct: 242 RKVELRFRHSYFPFVEPGIEVDISCECHGAGCSLCKHAGWLEVAGAGMIHPNVLRKASID 301
Query: 459 --KVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLRE 495
+ A G+GI+RLAM K GI DIR DLR+LR+
Sbjct: 302 PEEYSGYALGMGIERLAMLKYGISDIRLFSENDLRFLRQ 340
>pir||B83303 phenylalanyl-tRNA synthetase, alpha-subunit PA2740 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9948818|gb|AAG06128.1|AE004702_5 (AE004702)
phenylalanyl-tRNA synthetase, alpha-subunit [Pseudomonas
aeruginosa]
Length = 338
Score = 82.3 bits (200), Expect = 1e-14
Identities = 71/284 (25%), Positives = 121/284 (42%), Gaps = 57/284 (20%)
Query: 225 NIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPA 284
++ P + G P L++I + +G+ E+ +E + NF+AL P +HPA
Sbjct: 93 DVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGY-EVAEGPEVEDDYHNFEALNIPGHHPA 151
Query: 285 REWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATA 344
R DT+ A +L+ R H +
Sbjct: 152 RAMHDTFYFN--------------------------------------ANMLL-RTHTSP 172
Query: 345 LSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRF 404
+ R + + + P + RV+R D D TH F+Q++G + E ++F L G ++ F
Sbjct: 173 VQVRTM-ESQQPPIRIVCPGRVYRCDS-DLTHSPMFHQVEGLLVDEGVSFADLKGTIEEF 230
Query: 405 AIEIAGAK-KVKFFPDYYPFTEPSVQLSAYH-----------PELGWVEFGGAGVFREEM 452
+ +V+F P ++PFTEPS ++ + GW+E G G+ +
Sbjct: 231 LRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNV 290
Query: 453 TEALGI---KVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWL 493
I K A+G+G +RLAM + G++D+R F DLR+L
Sbjct: 291 LRMSNIDPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFL 334
>pir||B72011 phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain [similarity] -
Chlamydophila pneumoniae (strains CWL029 and AR39)
>gi|4377321|gb|AAD19130.1| (AE001679) Phenylalanyl tRNA
Synthetase, Alpha [Chlamydophila pneumoniae CWL029]
>gi|7189774|gb|AAF38651.1| (AE002245) phenylalanyl-tRNA
synthetase alpha chain [Chlamydophila pneumoniae AR39]
>gi|8979366|dbj|BAA99200.1| (AP002548) phenylalanyl tRNA
synthetase, alpha [Chlamydophila pneumoniae J138]
Length = 339
Score = 81.1 bits (197), Expect = 3e-14
Identities = 89/374 (23%), Positives = 155/374 (40%), Gaps = 65/374 (17%)
Query: 144 LKLLSEKGEVSVDEISRIIDVKDLKRRKIARED---ERVERTVEITEKGKKLVSKGIELK 200
++ + ++ +D+++ + DLK R + ++ E+ + T+K K L S + K
Sbjct: 7 IEAVKQQFHSELDQVNSSQALADLKVRYLGKKGIFRSFSEKLKQCTDKAK-LGSLINDFK 65
Query: 201 REVTRLTPE----LIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMG 256
V L E L+AS + + + P G + + LD + + +G
Sbjct: 66 TYVEDLLQEKSLVLLASEQAEAFSKEKIDSSLPGDSQPSGGRHILKSILDDVVDIFVHLG 125
Query: 257 FIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHER 316
F + IE++ NF L ++HPAR+ DT+ L
Sbjct: 126 FCVREAPN-IESEANNFTLLNFTEDHPARQMHDTFYLN---------------------- 162
Query: 317 GLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFR-PDVLDRT 375
+ R H + + AR+L K + P K FR D+ R+
Sbjct: 163 -----------------ATTVLRTHTSNVQARELKKQ-QPPIKVVAPGLCFRNEDISARS 204
Query: 376 HLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLS--- 431
H++ F+Q++ F ++TF L IL F K +++F Y+PF EP +++
Sbjct: 205 HVL-FHQVEAFYVDHNVTFSDLTAILSAFYHSFFQRKTELRFRHSYFPFVEPGIEVDVSC 263
Query: 432 -------AYHPELGWVEFGGAGVFREEMTEALGIKVPVI---AWGIGIDRLAMFKLGIDD 481
A GW+E GAG+ ++ + + A G+GI+RLAM K G+ D
Sbjct: 264 ECCGKGCALCKHTGWLEVAGAGMIHPQVLRNGNVDPEIYSGYAVGMGIERLAMLKYGVSD 323
Query: 482 IRYLFSYDLRWLRE 495
IR DLR+L++
Sbjct: 324 IRLFSENDLRFLQQ 337
>pir||T45974 phenylalanine-tRNA synthetase-like protein - Arabidopsis thaliana
>gi|6735326|emb|CAB68152.1| (AL137081)
phenylalanine-tRNA synthetase-like protein [Arabidopsis
thaliana]
Length = 435
Score = 79.6 bits (193), Expect = 8e-14
Identities = 67/242 (27%), Positives = 107/242 (43%), Gaps = 56/242 (23%)
Query: 264 SLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRG 323
S I T NFD + P +H +R DTY Y+ ++++
Sbjct: 129 SPIVTTKQNFDDVLVPADHVSRSLNDTY--------YVDSQTVL---------------- 164
Query: 324 WGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQI 383
R H +A A L KG ++ V+R D +D TH F+Q+
Sbjct: 165 ---------------RCHTSAHQAELLRKG---HSRFLVTGDVYRRDSIDSTHYPVFHQM 206
Query: 384 DGFV---------AGEDLTF---RHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLS 431
+GF +G+D T L L+ A + G+ ++++ Y+PFT PS +L
Sbjct: 207 EGFCVFSPEDWNGSGKDSTLYAAEDLKKCLEGLARHLFGSVEMRWVDTYFPFTNPSFELE 266
Query: 432 AYHPELGWVEFGGAGVFREEMTEALGIKVPVI-AWGIGIDRLAMFKLGIDDIRYLFSYDL 490
Y E W+E G GV + + + G++ V A+G+G++RLAM I DIR+ +S D
Sbjct: 267 IYFKE-DWLEVLGCGVTEQVILKQSGLENNVAWAFGLGLERLAMVLFDIPDIRFFWSSDE 325
Query: 491 RW 492
R+
Sbjct: 326 RF 327
>pir||F81727 phenylalanyl-tRNA synthetase, alpha chain TC0224 [imported] -
Chlamydia muridarum (strain Nigg)
>gi|7190263|gb|AAF39096.1| (AE002289) phenylalanyl-tRNA
synthetase, alpha subunit [Chlamydia muridarum]
Length = 341
Score = 79.2 bits (192), Expect = 1e-13
Identities = 74/305 (24%), Positives = 128/305 (41%), Gaps = 65/305 (21%)
Query: 210 LIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQ 269
++A + E + ++ P + G K + LD + + GF + IE++
Sbjct: 81 ILAKEEAEEFLKEKVDVSLPGEDAPLGGKHIIKKVLDDVVDIFVRFGFCVREAPN-IESE 139
Query: 270 FWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWS 329
NF L ++HPAR+ DT+ YL +++
Sbjct: 140 KNNFSLLNFEEDHPARQMQDTF--------YLDPVTVL---------------------- 169
Query: 330 PERAMLLMPRAHATALSARQLAKG-----IEIPGKYFTIQRVFRPDVLDRTHLIEFNQID 384
R H + + +R+LA+ + PG+ F + D+ R+H + F+Q++
Sbjct: 170 ---------RTHTSNVQSRELARNKPPVRVVAPGECFRNE-----DISARSH-VTFHQVE 214
Query: 385 GFVAGEDLTFRHLLGILKRFAIEIAGAK-KVKFFPDYYPFTEPSVQLS----------AY 433
F D++F L +L F G K ++++ Y+PF EP +++ +
Sbjct: 215 AFHVDRDVSFSDLTSMLSGFYHIFFGRKVELRYRHSYFPFVEPGIEVDISCECRGAGCSL 274
Query: 434 HPELGWVEFGGAGVFREEMTEALGI---KVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDL 490
GW+E GAG+ + I + A G+GI+RLAM K GI DIR DL
Sbjct: 275 CKHSGWLEVAGAGMIHPNVLRQANIDPEEYSGYALGMGIERLAMLKYGISDIRLFSENDL 334
Query: 491 RWLRE 495
R+LR+
Sbjct: 335 RFLRQ 339
>pir||B64507 hypothetical protein MJ1660 - Methanococcus jannaschii
>gi|1500562|gb|AAB99678.1| (U67606) phenylalanyl-tRNA
synthase alpha subunit [Methanococcus jannaschii]
Length = 549
Score = 76.9 bits (186), Expect = 5e-13
Identities = 57/167 (34%), Positives = 85/167 (50%), Gaps = 19/167 (11%)
Query: 330 PERAMLLMPRAHATA---LSARQLAKGIEIPGKYFTIQRVFRPDVL-DRTHLIEFNQIDG 385
PE L + R+H T+ ++ L K ++P K F+I R FR + DR+HL+ ++
Sbjct: 188 PESTTLTL-RSHMTSGWFITLSSLIKKRKLPLKLFSIDRCFRREQREDRSHLMSYHSASC 246
Query: 386 FVAGEDLTFRH----LLGILKRFAIEIAGAKKVKFFPDY----YPFTEPSVQLSAYHPEL 437
V GED++ G+L +F G K KF PD Y E ++ AYHP+L
Sbjct: 247 VVVGEDVSVDDGKVVAEGLLAQF-----GFTKFKFKPDEKKSKYYTPETQTEVYAYHPKL 301
Query: 438 G-WVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDIR 483
G W+E GV+ I VPV+ G+G++RLAM G +D+R
Sbjct: 302 GEWIEVATFGVYSPIALAKYNIDVPVMNLGLGVERLAMIIYGYEDVR 348
>sp|P47436|SYFA_MYCGE PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA
LIGASE ALPHA CHAIN) (PHERS) >gi|1361746|pir||D64221
phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain -
Mycoplasma genitalium >gi|3844791|gb|AAC71412.1|
(U39699) phenylalanyl-tRNA synthetase, subunit alpha
(pheS) [Mycoplasma genitalium]
Length = 341
Score = 75.3 bits (182), Expect = 1e-12
Identities = 53/181 (29%), Positives = 85/181 (46%), Gaps = 16/181 (8%)
Query: 331 ERAMLLMPRAHATALSARQLAKGIEIPG-KYFTIQRVFRPDVLDRTHLIEFNQIDGFVAG 389
++ LL AT L A + +K P + ++ VFR D D TH +F Q+D
Sbjct: 158 DKTSLLRTHCTATTLKAVRTSKKTNNPDIRVVSLGAVFRNDSDDATHSHQFTQLDFMWIK 217
Query: 390 EDLTFRHLLGILKRFAIEIAGAKK-VKFFPDYYPFTEPSVQLS----------AYHPELG 438
+ L+ +L + G +F ++PFTEPS ++ + +
Sbjct: 218 KGLSLANLKWFINNMITHFFGENTFTRFRLSHFPFTEPSFEIDIRCWLCQNGCSICKQTK 277
Query: 439 WVEFGGAGVFREEMTEALGI----KVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLR 494
W+E GAG+ ++ +GI + IA GIGI+RLAM K GIDDIR + + ++L
Sbjct: 278 WIEILGAGIIHPQVMNNMGIGDTENITGIAAGIGIERLAMLKYGIDDIRDFYDNNFKFLT 337
Query: 495 E 495
+
Sbjct: 338 Q 338
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.141 0.406
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 181561641
Number of Sequences: 2977
Number of extensions: 7920017
Number of successful extensions: 25273
Number of sequences better than 1.0e-10: 55
Number of HSP's better than 0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 25030
Number of HSP's gapped (non-prelim): 93
length of query: 500
length of database: 189,106,746
effective HSP length: 56
effective length of query: 444
effective length of database: 155,591,474
effective search space: 69082614456
effective search space used: 69082614456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 167 (69.5 bits)