2

Mining Archaeal Proteomes for Eukaryotic Proteins with Novel Functions

 

 

PACE 2

Orthologs in Archaea

Gene

Blast Expect

Paralogs

Pyrococcus abyssi

PAB0133

e-169

 

Pyrococcus furiosus

Pf_136581

3e-58

 

Pyrococcus horikoshii

PH0216

1e-107

 

Aeropyrum pernix

 

 

 

Archaeoglobus fulgidus

AF0447

5e-23

AF0446

Methanobacterium thermoautotrophicum

 

 

 

Methanococcus jannaschii

 

 

 

Homologs in Eucarya

Human

 

Yeast

 

Other

F6E13.19  A. thaliana

 

Size of P. abyssi protein

296 aa.

Best Hits outside Archaea

Gene

Blast Expect

 

Best Eucaryotic Hit

F6E13.19  

7e-04

 A. thaliana

Best Bacterial Hit

AAC45010.1

2.3

S. enterica

 

Module (Pfam, Prosite, Prints)

Initiation and regulation of replication

PRODOM domain

LEA-like (Late embryogenesis)

PDB hit

 

COG group

 

Gene Environment in Archaea

Not conserved:
not highly conserved/ unknown/ Repair/ ribosomal proteins

See Environment

Phylogeny

 See Unrooted Distance Tree

 

Function Prediction

 Informational