Sulfolobus solfataricus P2

 

Sulfolobus P2 hits in COG database:

 

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STATUS legend:
good         =  match length > 50 % of orf length, number of best COG matches > 1/4 total number of matched COGs
suspect: MH  =  multiple hits in COG database, number of best COG matches < 1/4 total number of matched COGs
suspect: LH  =  Less than 3 Hits in COG database
suspect: HSP =  match length <= 40 % of orf length
suspect: Pn  =  expect value (Pn) for best match is near cut off value (1e-07)
suspect: %id =  % identity of best hits is less than 25% over matched length
normal       =  all the rest

ORF STATUS Function Best COG Functional category Pathways and functional systems Code
SSO0002 good H COG0351 Coenzyme metabolism Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase SSO0004 good G COG0524 Carbohydrate transport and metabolism Sugar kinases, ribokinase family SSO0006 good R COG1234 General function prediction only Metal-dependent hydrolases of the beta-lactamase superfamily III SSO0008 suspect: Pn L COG0675 DNA replication, recombination and repair Predicted transposases SSO0009 good R COG0123 General function prediction only Deacetylases, including yeast histone deacetylase and acetoin utilization protein SSO0010 good E COG0006 Amino acid transport and metabolism Xaa-Pro aminopeptidase SSO0011 suspect: LH S COG1361 Function unknown Predicted membrane protein SSO0015 good R COG0730 General function prediction only Predicted permeases SSO0016 normal R COG0603 General function prediction only Predicted ATPase (PP-loop superfamily), confers aluminum resistance SSO0017 check: MH R COG1205 General function prediction only Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster SSO0019 good H COG0521 Coenzyme metabolism Molybdopterin biosynthesis enzymes SSO0021 suspect: LH R COG0665 General function prediction only Predicted oxidoreductases SSO0026 check: MH F COG0027 Nucleotide transport and metabolism Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) PurT SSO0028 good R COG0123 General function prediction only Deacetylases, including yeast histone deacetylase and acetoin utilization protein SSO0029 good R COG0517 General function prediction only CBS domains SSO0031 good R COG0388 General function prediction only Predicted amidohydrolase SSO0034 good D COG1192 Cell division and chromosome partitioning ATPases involved in chromosome partitioning SSO0038 suspect: LH K COG1695 Transcription Predicted transcriptional regulators SSO0039 good S COG1992 Function unknown Uncharacterized ACR SSO0044 normal C COG0843 Energy production and conversion Cytochrome c oxidase, heme b and copper-binding subunit SSO0046 good R COG0084 General function prediction only Predicted hydrolases of PHP superfamily SSO0049 good K COG1695 Transcription Predicted transcriptional regulators SSO0050 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO0052 good O COG0309 Posttranslational modification, protein turnover, chaperones Hydrogenase formation factor SSO0053 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO0054 suspect: LH M COG1208 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis/translation and initiation factor eIF2B subunits SSO0060 good M COG0472 Cell envelope biogenesis, outer membrane UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase SSO0061 good H COG0142 Coenzyme metabolism Geranylgeranyl pyrophosphate synthase SSO0063 good C COG1304 Energy production and conversion L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases SSO0064 good R COG1608 General function prediction only Predicted archaeal kinases SSO0066 good S COG1355 Function unknown Uncharacterized ACR SSO0067 good J COG0052 Translation, ribosomal structure and biogenesis Ribosomal protein S2 SSO0068 good J COG0103 Translation, ribosomal structure and biogenesis Ribosomal protein S9 SSO0069 good J COG0102 Translation, ribosomal structure and biogenesis Ribosomal protein L13 SSO0070 good J COG1727 Translation, ribosomal structure and biogenesis Ribosomal protein L18E SSO0071 good K COG0202 Transcription DNA-dependent RNA polymerase alpha subunit SSO0072 good J COG0100 Translation, ribosomal structure and biogenesis Ribosomal protein S11 SSO0073 good J COG0522 Translation, ribosomal structure and biogenesis Ribosomal protein S4 and related proteins SSO0074 good J COG0099 Translation, ribosomal structure and biogenesis Ribosomal protein S13 SSO0076 good O COG1973 Posttranslational modification, protein turnover, chaperones Hydrogenase expression/formation protein HypE SSO0078 good J COG0162 Translation, ribosomal structure and biogenesis Tyrosyl-tRNA synthetase SSO0079 good L COG0358 DNA replication, recombination and repair DNA primase (bacterial type) SSO0081 good L COG0417 DNA replication, recombination and repair DNA-dependent DNA polymerase elongation subunit (family B) SSO0082 good R COG0456 General function prediction only Acetyltransferases SSO0083 good R COG1537 General function prediction only Predicted RNA-binding proteins SSO0084 good R COG2108 General function prediction only Uncharacterized ArCR related to pyruvate formate-lyase activating enzyme SSO0087 good M COG0750 Cell envelope biogenesis, outer membrane Predicted membrane-associated Zn-dependent proteases 1 SSO0090 good J COG1190 Translation, ribosomal structure and biogenesis Lysyl-tRNA synthetases SSO0091 good J COG1358 Translation, ribosomal structure and biogenesis Ribosomal protein HS6-type (S12/L30/L7a) SSO0093 good J COG0008 Translation, ribosomal structure and biogenesis Glutamyl- and glutaminyl-tRNA synthetases SSO0094 good R COG0561 General function prediction only Predicted hydrolases of the HAD superfamily SSO0095 good R COG1078 General function prediction only HD superfamily phosphohydrolases SSO0098 good J COG0024 Translation, ribosomal structure and biogenesis Methionine aminopeptidase SSO0099 good R COG2220 General function prediction only Predicted Zn-dependent hydrolases of the beta-lactamase fold SSO0100 good J COG0016 Translation, ribosomal structure and biogenesis Phenylalanyl-tRNA synthetase alpha subunit SSO0101 good J COG0072 Translation, ribosomal structure and biogenesis Phenylalanyl-tRNA synthetase beta subunit SSO0102 normal R COG0596 General function prediction only Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) SSO0103 good S COG1058 Function unknown Uncharacterized ACR SSO0104 check: MH K COG1167 Transcription Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs SSO0110 good R COG0517 General function prediction only CBS domains SSO0112 check: MH R COG1201 General function prediction only Lhr-like helicases SSO0114 suspect: %id M COG1215 Cell envelope biogenesis, outer membrane Glycosyltransferases, probably involved in cell wall biogenesis SSO0116 good L COG0177 DNA replication, recombination and repair Predicted EndoIII-related endonuclease SSO0120 good N COG0630 Cell motility and secretion Predicted ATPases involved in pili biogenesis SSO0122 good J COG0144 Translation, ribosomal structure and biogenesis Predicted rRNA methylase SSO0125 good H COG0382 Coenzyme metabolism 4-hydroxybenzoate octaprenyltranferase SSO0127 good E COG0119 Amino acid transport and metabolism Isopropylmalate/homocitrate/citramalate synthases SSO0128 good P COG0614 Inorganic ion transport and metabolism Ferrichrome-binding periplasmic proteins SSO0129 suspect: LH H COG2073 Coenzyme metabolism Cobalamin biosynthesis protein CbiG SSO0143 suspect: LH L COG0582 DNA replication, recombination and repair Integrase SSO0144 good P COG1055 Inorganic ion transport and metabolism Arsenite permease SSO0151 good M COG0794 Cell envelope biogenesis, outer membrane Predicted sugar phosphate aminotransferases involved in capsule formation SSO0152 suspect: LH R COG0433 General function prediction only Predicted ATPase SSO0155 good E COG0002 Amino acid transport and metabolism Acetylglutamate semialdehyde dehydrogenase SSO0156 good E COG0548 Amino acid transport and metabolism Acetylglutamate kinase SSO0157 good K COG1522 Transcription Transcriptional regulators, Lrp family SSO0159 good H COG0189 Coenzyme metabolism Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) SSO0160 good E COG0160 Amino acid transport and metabolism PLP-dependent aminotransferases SSO0162 good E COG0624 Amino acid transport and metabolism Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SSO0163 good I COG0020 Lipid metabolism Undecaprenyl pyrophosphate synthase SSO0164 good J COG2007 Translation, ribosomal structure and biogenesis Ribosomal protein S8E SSO0166 good M COG0451 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar epimerases SSO0167 check: MH P COG1122 Inorganic ion transport and metabolism ABC-type cobalt transport system, ATPase component SSO0170 good E COG0028 Amino acid transport and metabolism Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] SSO0172 suspect: LH K COG0195 Transcription Transcription terminator NusA SSO0173 good J COG0017 Translation, ribosomal structure and biogenesis Aspartyl/asparaginyl-tRNA synthetases SSO0174 good S COG0585 Function unknown Uncharacterized ACR, YgbO/UPF0024 family SSO0175 good S COG1990 Function unknown Uncharacterized ACR SSO0176 good O COG0464 Posttranslational modification, protein turnover, chaperones AAA+ class ATPases SSO0179 good L COG0258 DNA replication, recombination and repair 5'-3' exonuclease (including N-terminal domain of PolI) SSO0180 good H COG0373 Coenzyme metabolism Glutamyl-tRNA reductase SSO0181 good H COG0113 Coenzyme metabolism Delta-aminolevulinic acid dehydratase SSO0182 check: MH H COG0001 Coenzyme metabolism Glutamate-1-semialdehyde aminotransferase SSO0183 good H COG0181 Coenzyme metabolism Porphobilinogen deaminase SSO0184 suspect: LH H COG1587 Coenzyme metabolism Uroporphyrinogen-III synthase HemD SSO0186 suspect: LH R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO0187 good R COG0665 General function prediction only Predicted oxidoreductases SSO0188 normal R COG1236 General function prediction only Predicted Zn-dependent hydrolases (beta-lactamase superfamily) SSO0189 good L COG1793 DNA replication, recombination and repair ATP-dependent DNA ligase SSO0190 good F COG0717 Nucleotide transport and metabolism Deoxycytidine deaminase SSO0192 good O COG0526 Posttranslational modification, protein turnover, chaperones Thiol-disulfide isomerase and thioredoxins SSO0193 good S COG2078 Function unknown Uncharacterized ACR SSO0194 good S COG1656 Function unknown Uncharacterized ACR SSO0195 good M COG1293 Cell envelope biogenesis, outer membrane Fibronectin-binding protein (function unknown) SSO0197 good T COG0478 Signal transduction mechanisms Predicted serine/threonine protein kinases SSO0198 suspect: %id L COG0419 DNA replication, recombination and repair ATPase involved in DNA repair SSO0199 good S COG1812 Function unknown Uncharacterized ACR SSO0200 good K COG0640 Transcription Predicted transcriptional regulators SSO0201 good F COG0504 Nucleotide transport and metabolism CTP synthase (UTP-ammonia lyase) SSO0202 good G COG0269 Carbohydrate transport and metabolism 3-hexulose-6-phosphate synthase and related proteins SSO0207 good G COG1109 Carbohydrate transport and metabolism Phosphomannomutase SSO0209 good R COG0456 General function prediction only Acetyltransferases SSO0210 good H COG0452 Coenzyme metabolism Flavoprotein involved in panthothenate metabolism SSO0212 good S COG1767 Function unknown Uncharacterized proteins, CitG homologs SSO0213 suspect: %id S COG1665 Function unknown Uncharacterized ArCR SSO0215 good J COG0051 Translation, ribosomal structure and biogenesis Ribosomal protein S10 SSO0216 good J COG0050 Translation, ribosomal structure and biogenesis GTPases - translation elongation factors and sulfate adenylate transferase subunit 1 SSO0217 good J COG0049 Translation, ribosomal structure and biogenesis Ribosomal protein S7 SSO0218 suspect: LH S COG1259 Function unknown Uncharacterized ACR SSO0219 good J COG0048 Translation, ribosomal structure and biogenesis Ribosomal protein S12 SSO0220 good K COG0195 Transcription Transcription terminator NusA SSO0221 good J COG1911 Translation, ribosomal structure and biogenesis Ribosomal protein L30E SSO0223 good K COG0086 Transcription DNA-dependent RNA polymerase beta' subunit (split gene in Mjan, Mthe, Aful, and Synechocystis) SSO0225 good K COG0086 Transcription DNA-dependent RNA polymerase beta' subunit (split gene in Mjan, Mthe, Aful, and Synechocystis) SSO0227 good K COG0085 Transcription DNA-dependent RNA polymerase beta subunit (split gene in Mjan, Mthe, Aful) SSO0228 good J COG0532 Translation, ribosomal structure and biogenesis Translation initiation factor 2 (GTPase) SSO0230 good F COG0105 Nucleotide transport and metabolism Nucleoside diphosphate kinase SSO0231 good F COG0035 Nucleotide transport and metabolism Uracil phosphoribosyltransferase SSO0232 good J COG0064 Translation, ribosomal structure and biogenesis Glu-tRNAGln amidotransferase B subunit (PET112 homolog) SSO0233 good F COG0503 Nucleotide transport and metabolism Adenine/guanine phosphoribosyltransferases SSO0235 good R COG1964 General function prediction only MoaA-related oxidoreductases II SSO0237 good H COG0611 Coenzyme metabolism Thiamine monophosphate kinase SSO0239 good R COG1759 General function prediction only ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) SSO0240 good F COG0015 Nucleotide transport and metabolism Adenylosuccinate lyase SSO0241 good R COG1759 General function prediction only ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) SSO0242 good F COG0104 Nucleotide transport and metabolism Adenylosuccinate synthase SSO0244 good R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO0245 suspect: LH K COG1522 Transcription Transcriptional regulators, Lrp family SSO0246 good E COG0077 Amino acid transport and metabolism Prephenate dehydratase SSO0248 good E COG1171 Amino acid transport and metabolism Threonine dehydratase SSO0249 good F COG0537 Nucleotide transport and metabolism Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases SSO0250 good L COG0468 DNA replication, recombination and repair RecA/RadA recombinase SSO0252 good J COG0144 Translation, ribosomal structure and biogenesis Predicted rRNA methylase SSO0253 good F COG1437 Nucleotide transport and metabolism Adenylate cyclase, class 2 (thermophilic) SSO0254 good S COG1912 Function unknown Uncharacterized ACR SSO0255 good H COG1056 Coenzyme metabolism Nicotinamide mononucleotide adenylyltransferase SSO0256 good S COG1628 Function unknown Uncharacterized ArCR SSO0257 good L COG1474 DNA replication, recombination and repair Cdc6-related protein, AAA superfamily ATPase SSO0258 good S COG1571 Function unknown Uncharacterized ArCR SSO0259 good R COG1646 General function prediction only Predicted phosphate-binding enzymes, TIM-barrel fold SSO0265 good L COG0270 DNA replication, recombination and repair Site-specific DNA methylase dcm SSO0266 good K COG1675 Transcription Transcription initiation factor IIE, large subunit SSO0267 good S COG1303 Function unknown Uncharacterized ArCR SSO0269 good R COG1159 General function prediction only Predicted GTPases, Era/HflX family SSO0270 good K COG1813 Transcription Predicted transcription factor, homolog of eukaryotic MBF1 SSO0271 check: MH O COG1222 Posttranslational modification, protein turnover, chaperones ATP-dependent 26S proteasome regulatory subunit SSO0274 good J COG0343 Translation, ribosomal structure and biogenesis Queuine/archaeosine tRNA-ribosyltransferase SSO0275 good J COG0343 Translation, ribosomal structure and biogenesis Queuine/archaeosine tRNA-ribosyltransferase SSO0278 good O COG0638 Posttranslational modification, protein turnover, chaperones Proteasome protease subunit HslV SSO0279 good J COG0124 Translation, ribosomal structure and biogenesis Histidyl-tRNA synthetase SSO0280 suspect: LH K COG1405 Transcription Transcription initiation factor IIB SSO0282 good O COG0459 Posttranslational modification, protein turnover, chaperones Chaperonin GroEL (HSP60 family) SSO0283 good R COG0433 General function prediction only Predicted ATPase SSO0286 good S COG1980 Function unknown Uncharacterized ACR SSO0287 check: MH R COG1245 General function prediction only RNase L inhibitor homolog, predicted ATPase SSO0290 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO0291 good K COG1594 Transcription DNA-directed RNA polymerase subunit M/Transcription elongation factor TFIIS SSO0292 good J COG1096 Translation, ribosomal structure and biogenesis Predicted RNA-binding proteins (consist of S1 domain and C4 Zn-finger domain) SSO0293 good J COG1736 Translation, ribosomal structure and biogenesis Diphthamide synthase subunit DPH2 SSO0294 good J COG0197 Translation, ribosomal structure and biogenesis Ribosomal protein L16/L10E SSO0297 good G COG0021 Carbohydrate transport and metabolism Transketolase SSO0298 good H COG0476 Coenzyme metabolism Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 SSO0299 good H COG1154 Coenzyme metabolism Deoxyxylulose-5-phosphate synthase SSO0302 good E COG0287 Amino acid transport and metabolism Prephenate dehydrogenase SSO0304 good E COG0722 Amino acid transport and metabolism DAHP synthase/3-Deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase SSO0305 good E COG0337 Amino acid transport and metabolism 3-dehydroquinate synthetase SSO0306 good E COG0169 Amino acid transport and metabolism Shikimate 5-dehydrogenase SSO0307 good E COG0082 Amino acid transport and metabolism Chorismate synthase SSO0308 good R COG1685 General function prediction only Uncharacterized archaeal kinases distantly related to homoserine/aspartokinases SSO0309 good E COG0128 Amino acid transport and metabolism 5-enolpyruvylshikimate-3-phosphate synthase SSO0311 good E COG0710 Amino acid transport and metabolism 3-dehydroquinate dehydratase SSO0313 good L COG1199 DNA replication, recombination and repair Rad3-related DNA helicases SSO0315 suspect: LH M COG1293 Cell envelope biogenesis, outer membrane Fibronectin-binding protein (function unknown) SSO0316 good P COG0605 Inorganic ion transport and metabolism Superoxide dismutase SSO0317 good M COG1208 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis/translation and initiation factor eIF2B subunits SSO0321 good S COG1351 Function unknown Uncharacterized ACR, THY1 family SSO0323 good C COG0852 Energy production and conversion NADH-ubiquinone oxidoreductase 27 kD subunit, NuoC/NQO5/Nad9 SSO0324 good C COG0649 Energy production and conversion Formate hydrogenlyase subunit 5 and NADH-ubiquinone oxidoreductase 49 kD subunit 7 (chain D), NuoD/NQO4/Nad7 SSO0325 good C COG1005 Energy production and conversion NADH-ubiquinone oxidoreductase subunit 1 (chain H), NuoH/NQO8/Nad1 SSO0326 good C COG1143 Energy production and conversion Formate hydrogenlyase subunit 6/NADH-ubiquinone oxidoreductase 23 kD subunit (chain I), NuoI/NQO9/FrxB SSO0328 suspect: HSP C COG0651 Energy production and conversion Formate hydrogenlyase subunit 3, HycC SSO0329 good C COG0651 Energy production and conversion Formate hydrogenlyase subunit 3, HycC SSO0330 good I COG1260 Lipid metabolism Myo-inositol-1-phosphate synthase SSO0333 good H COG0301 Coenzyme metabolism Enzyme of thiamine biosynthesis (ThiI); contains a PP-loop superfamily ATPase domain and an uncharacterized conserved domain SSO0341 good J COG0013 Translation, ribosomal structure and biogenesis Alanyl-tRNA synthetase SSO0342 good J COG2058 Translation, ribosomal structure and biogenesis Ribosomal protein L12E SSO0344 good J COG0244 Translation, ribosomal structure and biogenesis Ribosomal protein L10 SSO0345 good J COG0081 Translation, ribosomal structure and biogenesis Ribosomal protein L1 SSO0346 good J COG0080 Translation, ribosomal structure and biogenesis Ribosomal protein L11 SSO0347 good K COG0250 Transcription Transcription antiterminator NusG/RfaH SSO0348 good N COG0552 Cell motility and secretion Signal recognition particle GTPase FtsY SSO0351 good J COG1976 Translation, ribosomal structure and biogenesis Eukaryotic translation initiation factor 6 (EIF6) SSO0352 good S COG2118 Function unknown Uncharacterized ACR SSO0353 good J COG2238 Translation, ribosomal structure and biogenesis Ribosomal protein S19E (S16A) SSO0354 good H COG1488 Coenzyme metabolism Nicotinic acid phosphoribosyltransferase SSO0356 good P COG0704 Inorganic ion transport and metabolism Phosphate uptake regulator SSO0360 good E COG0031 Amino acid transport and metabolism Cysteine synthase/cystathionine beta-synthase SSO0362 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO0363 good E COG0006 Amino acid transport and metabolism Xaa-Pro aminopeptidase SSO0364 good H COG0302 Coenzyme metabolism GTP cyclohydrolase I SSO0366 good E COG0174 Amino acid transport and metabolism Glutamine synthase SSO0367 check: MH P COG1118 Inorganic ion transport and metabolism ABC-type sulfate/molybdenum transport system, ATPase component SSO0368 good O COG0526 Posttranslational modification, protein turnover, chaperones Thiol-disulfide isomerase and thioredoxins SSO0369 check: MH H COG2228 Coenzyme metabolism o-Succinylbenzoate-CoA synthase SSO0370 good R COG1907 General function prediction only Predicted archaeal sugar kinases SSO0371 good J COG0144 Translation, ribosomal structure and biogenesis Predicted rRNA methylase SSO0372 good R COG0663 General function prediction only Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily SSO0373 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO0375 good L COG0582 DNA replication, recombination and repair Integrase SSO0376 suspect: %id P COG0475 Inorganic ion transport and metabolism K efflux system, membrane domain SSO0377 good S COG2096 Function unknown Uncharacterized ACR SSO0381 good M COG1208 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis/translation and initiation factor eIF2B subunits SSO0382 good M COG0449 Cell envelope biogenesis, outer membrane Glucosamine-fructose-6-phosphate aminotransferase, contains aminotransferase and phosphosugar isomerase domains SSO0383 good I COG1577 Lipid metabolism Mevalonate kinase SSO0384 suspect: HSP J COG0441 Translation, ribosomal structure and biogenesis Threonyl-tRNA synthetase SSO0385 good K COG1308 Transcription Transcription factor homologous to NACalpha-BTF3 SSO0386 good R COG1236 General function prediction only Predicted Zn-dependent hydrolases (beta-lactamase superfamily) SSO0387 good K COG1709 Transcription Predicted transcriptional regulators SSO0388 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO0391 good S COG1444 Function unknown Uncharacterized ACR SSO0392 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0393 good J COG0130 Translation, ribosomal structure and biogenesis Pseudouridine synthase SSO0394 check: MH R COG1201 General function prediction only Lhr-like helicases SSO0395 suspect: %id R COG0433 General function prediction only Predicted ATPase SSO0397 suspect: %id L COG0592 DNA replication, recombination and repair DNA polymerase III beta subunit SSO0398 good F COG0402 Nucleotide transport and metabolism Cytosine deaminase and related metal-dependent hydrolases SSO0400 good H COG0054 Coenzyme metabolism Riboflavin synthase beta-chain SSO0401 good H COG1731 Coenzyme metabolism Archaeal riboflavin synthase SSO0402 good H COG0108 Coenzyme metabolism 3,4-dihydroxy-2-butanone 4-phosphate synthase SSO0404 good H COG1797 Coenzyme metabolism Cobyrinic acid a,c-diamide synthase CobB SSO0405 good L COG0592 DNA replication, recombination and repair DNA polymerase III beta subunit SSO0406 good E COG0620 Amino acid transport and metabolism Methionine synthase II (cobalamin-independent) SSO0407 good E COG0620 Amino acid transport and metabolism Methionine synthase II (cobalamin-independent) SSO0408 good J COG0184 Translation, ribosomal structure and biogenesis Ribosomal protein S15P/S13E SSO0410 good S COG2138 Function unknown Uncharacterized ACR, YlnE family SSO0411 normal J COG2125 Translation, ribosomal structure and biogenesis Ribosomal protein S6E (S10) SSO0412 good J COG0050 Translation, ribosomal structure and biogenesis GTPases - translation elongation factors and sulfate adenylate transferase subunit 1 SSO0414 good R COG1412 General function prediction only Uncharacterized proteins of PilT N-term./Vapc superfamily SSO0415 good K COG1095 Transcription DNA-directed RNA polymerase subunit E SSO0416 good S COG1909 Function unknown Uncharacterized ArCR SSO0417 good G COG1015 Carbohydrate transport and metabolism Phosphopentomutase and related enzymes SSO0420 check: MH L COG1110 DNA replication, recombination and repair Reverse gyrase SSO0421 good O COG0464 Posttranslational modification, protein turnover, chaperones AAA+ class ATPases SSO0422 good R COG0388 General function prediction only Predicted amidohydrolase SSO0426 good K COG1378 Transcription Predicted transcriptional regulators SSO0427 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0430 good C COG0667 Energy production and conversion Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) SSO0432 good F COG0127 Nucleotide transport and metabolism Xanthosine triphosphate pyrophosphatase, HAM1/YggV family SSO0433 good T COG0515 Signal transduction mechanisms Serine/threonine protein kinases SSO0434 good O COG0533 Posttranslational modification, protein turnover, chaperones Metal-dependent proteases with possible chaperone activity SSO0435 good J COG2004 Translation, ribosomal structure and biogenesis Ribosomal protein S24E SSO0436 good R COG1635 General function prediction only Flavoproteins, possibly involved in thiazole biosynthesis SSO0437 good H COG0163 Coenzyme metabolism 3-octaprenyl-4-hydroxybenzoate decarboxylase SSO0439 good J COG1676 Translation, ribosomal structure and biogenesis tRNA splicing endonuclease SSO0444 good J COG0423 Translation, ribosomal structure and biogenesis Glycyl-tRNA synthetase, class II SSO0445 good E COG0010 Amino acid transport and metabolism Arginase/agmatinase/formimionoglutamate hydrolase, arginase family SSO0446 good K COG1405 Transcription Transcription initiation factor IIB SSO0448 good E COG0079 Amino acid transport and metabolism Histidinol-phosphate aminotransferase SSO0449 suspect: LH S COG2246 Function unknown Uncharacterized membrane protein SSO0450 good J COG0013 Translation, ribosomal structure and biogenesis Alanyl-tRNA synthetase SSO0452 good J COG0180 Translation, ribosomal structure and biogenesis Tryptophanyl-tRNA synthetase SSO0453 good S COG1801 Function unknown Uncharacterized ACR SSO0455 suspect: LH S COG1280 Function unknown Conserved membrane proteins, YahN/YigJ family SSO0456 good H COG0212 Coenzyme metabolism 5-formyltetrahydrofolate cyclo-ligase SSO0460 good D COG0489 Cell division and chromosome partitioning ATPases involved in chromosome partitioning, mrp family SSO0461 good F COG1936 Nucleotide transport and metabolism Predicted nucleotide kinase (related to CMP and AMP kinases) SSO0463 good R COG0705 General function prediction only Uncharacterized membrane protein (homolog of Drosophila rhomboid) SSO0464 good R COG1994 General function prediction only Zn-dependent proteases SSO0466 suspect: LH R COG1033 General function prediction only Membrane proteins related to SecD/SecF SSO0468 normal S COG1992 Function unknown Uncharacterized ACR SSO0469 suspect: LH R COG0433 General function prediction only Predicted ATPase SSO0470 suspect: LH J COG0050 Translation, ribosomal structure and biogenesis GTPases - translation elongation factors and sulfate adenylate transferase subunit 1 SSO0472 check: MH C COG1062 Energy production and conversion Alcohol dehydrogenase class III and related dehydrogenases SSO0473 good L COG1061 DNA replication, recombination and repair DNA or RNA helicases of superfamily II SSO0477 good C COG1032 Energy production and conversion Fe-S oxidoreductases family 2 SSO0478 normal R COG0312 General function prediction only Predicted Zn-dependent proteases and their inactivated homologs SSO0479 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0480 good K COG1243 Transcription ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetyltransferase domain (only BioB/LipA-like domain in Thermotoga) SSO0481 good R COG0546 General function prediction only Predicted phosphatases SSO0484 suspect: %id N COG0805 Cell motility and secretion Sec-independent protein secretion pathway component TatC SSO0485 suspect: %id P COG0614 Inorganic ion transport and metabolism Ferrichrome-binding periplasmic proteins SSO0486 good P COG0609 Inorganic ion transport and metabolism Iron, hemin, cobalamine permeases SSO0487 check: MH P COG1120 Inorganic ion transport and metabolism ABC-type iron (III) transport system, ATPase component SSO0488 check: MH P COG1117 Inorganic ion transport and metabolism ABC-type phosphate transport system, ATPase component SSO0489 good P COG0226 Inorganic ion transport and metabolism Periplasmic phosphate-binding protein SSO0490 good P COG0573 Inorganic ion transport and metabolism Phosphate permease SSO0491 good P COG0581 Inorganic ion transport and metabolism Phosphate permease component of ATP-dependent phosphate uptake system SSO0493 good E COG0498 Amino acid transport and metabolism Threonine synthase SSO0494 good S COG1801 Function unknown Uncharacterized ACR SSO0495 good E COG0345 Amino acid transport and metabolism Pyrroline-5-carboxylate reductase SSO0504 good J COG0495 Translation, ribosomal structure and biogenesis Leucyl-tRNA synthetase SSO0505 good F COG1957 Nucleotide transport and metabolism Inosine-uridine nucleoside N-ribohydrolase SSO0511 normal L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO0527 good G COG0126 Carbohydrate transport and metabolism 3-phosphoglycerate kinase SSO0528 good G COG0057 Carbohydrate transport and metabolism Glyceraldehyde-3-phosphate dehydrogenase SSO0529 suspect: Pn T COG0589 Signal transduction mechanisms Universal stress protein UspA and related nucleotide-binding proteins SSO0530 good E COG0112 Amino acid transport and metabolism Glycine hydroxymethyltransferase SSO0531 good I COG1257 Lipid metabolism Hydroxymethylglutaryl-CoA reductase SSO0532 good S COG1545 Function unknown Uncharacterized ACR SSO0534 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO0535 good I COG0332 Lipid metabolism 3-oxoacyl-[acyl-carrier-protein] synthase III SSO0536 good S COG1586 Function unknown Uncharacterized ACR SSO0541 suspect: HSP L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO0544 good R COG0603 General function prediction only Predicted ATPase (PP-loop superfamily), confers aluminum resistance SSO0546 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO0548 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO0550 suspect: LH S COG0668 Function unknown Uncharacterized ACR, integral membrane protein, YjeP/UPF0003 family SSO0551 good S COG2042 Function unknown Uncharacterized ACR SSO0552 good L COG0417 DNA replication, recombination and repair DNA-dependent DNA polymerase elongation subunit (family B) SSO0554 suspect: LH R COG0500 General function prediction only SAM-dependent methyltransferases SSO0556 good I COG0558 Lipid metabolism Phosphatidylglycerophosphate synthase SSO0557 suspect: LH L COG2219 DNA replication, recombination and repair Eukaryotic-type DNA primase, large subunit SSO0558 good J COG0143 Translation, ribosomal structure and biogenesis Methionyl-tRNA synthetase SSO0559 suspect: %id C COG1269 Energy production and conversion Archaeal/vacuolar-type H+-ATPase subunit I SSO0563 check: MH C COG1155 Energy production and conversion Vacuolar ATPase/archaeal ATP synthase A subunit (NtpA) SSO0564 check: MH C COG1156 Energy production and conversion Vacuolar ATPase/archaeal ATP synthase B subunit (NtpB) SSO0566 good C COG1394 Energy production and conversion Archaeal/vacuolar type H+-ATPase subunit D SSO0569 good J COG0442 Translation, ribosomal structure and biogenesis Prolyl-tRNA synthetase SSO0570 good F COG0214 Nucleotide transport and metabolism Predicted phosphate-utilizing enzyme involved in pyridoxine/purine/histidine biosynthesis SSO0571 good F COG0311 Nucleotide transport and metabolism Glutamine amidotransferase (possibly involved in histidine and purine biosynthesis) SSO0572 good R COG1855 General function prediction only ATPases of the PilT family SSO0575 good L COG1591 DNA replication, recombination and repair Holliday junction resolvase - archaeal type SSO0576 good E COG0059 Amino acid transport and metabolism Ketol-acid reductoisomerase (isoleucine biosynthesis) SSO0579 good E COG0028 Amino acid transport and metabolism Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] SSO0580 suspect: LH R COG0546 General function prediction only Predicted phosphatases SSO0581 good R COG1161 General function prediction only Predicted GTPases SSO0583 good H COG0382 Coenzyme metabolism 4-hydroxybenzoate octaprenyltranferase SSO0584 suspect: LH C COG0644 Energy production and conversion Dehydrogenases (flavoproteins) SSO0585 good S COG1586 Function unknown Uncharacterized ACR SSO0586 good R COG0037 General function prediction only Predicted ATPases of the PP-loop superamily SSO0588 good S COG2096 Function unknown Uncharacterized ACR SSO0589 good J COG0495 Translation, ribosomal structure and biogenesis Leucyl-tRNA synthetase SSO0592 good E COG0079 Amino acid transport and metabolism Histidinol-phosphate aminotransferase SSO0593 good E COG0040 Amino acid transport and metabolism ATP phosphoribosyltransferase (histidine biosynthesis) SSO0594 good E COG0106 Amino acid transport and metabolism Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase SSO0596 good E COG0131 Amino acid transport and metabolism Imidazoleglycerol-phosphate dehydratase SSO0597 good E COG0107 Amino acid transport and metabolism Imidazoleglycerol-phosphate synthase SSO0599 good E COG0141 Amino acid transport and metabolism Histidinol dehydrogenase SSO0600 good E COG0118 Amino acid transport and metabolism Glutamine amidotransferase (HisH) SSO0601 good R COG2151 General function prediction only Putative aromatic ring hydroxylating enzyme SSO0602 good J COG0172 Translation, ribosomal structure and biogenesis Seryl-tRNA synthetase SSO0604 good C COG1032 Energy production and conversion Fe-S oxidoreductases family 2 SSO0605 suspect: LH K COG1594 Transcription DNA-directed RNA polymerase subunit M/Transcription elongation factor TFIIS SSO0606 good K COG1522 Transcription Transcriptional regulators, Lrp family SSO0607 good S COG2095 Function unknown Integral membrane proteins of the MarC family SSO0610 good F COG0167 Nucleotide transport and metabolism Dihydroorotate dehydrogenase SSO0611 good F COG0044 Nucleotide transport and metabolism Dihydroorotase SSO0613 good F COG1781 Nucleotide transport and metabolism Aspartate carbamoyltransferase regulatory subunit SSO0614 good F COG0540 Nucleotide transport and metabolism Aspartate carbamoyltransferase, catalytic chain SSO0615 good F COG0461 Nucleotide transport and metabolism Orotate phosphoribosyltransferase SSO0616 good F COG0284 Nucleotide transport and metabolism Orotidine-5'-phosphate decarboxylase SSO0618 good P COG0704 Inorganic ion transport and metabolism Phosphate uptake regulator SSO0622 good S COG1590 Function unknown Uncharacterized ACR SSO0624 good O COG0602 Posttranslational modification, protein turnover, chaperones Organic radical activating enzymes SSO0625 check: MH R COG1084 General function prediction only Predicted GTPase SSO0626 good F COG0152 Nucleotide transport and metabolism Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase SSO0627 good R COG0073 General function prediction only EMAP domain SSO0628 good F COG0047 Nucleotide transport and metabolism Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain SSO0629 good F COG0046 Nucleotide transport and metabolism Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain SSO0632 good F COG0034 Nucleotide transport and metabolism Glutamine phosphoribosylpyrophosphate amidotransferase SSO0633 good F COG0034 Nucleotide transport and metabolism Glutamine phosphoribosylpyrophosphate amidotransferase SSO0635 good F COG0151 Nucleotide transport and metabolism Phosphoribosylamine-glycine ligase SSO0636 good F COG0150 Nucleotide transport and metabolism Phosphoribosylaminoimidazol (AIR) synthetase PurM SSO0638 good E COG0137 Amino acid transport and metabolism Argininosuccinate synthase SSO0639 good E COG0165 Amino acid transport and metabolism Argininosuccinate lyase SSO0640 good E COG0505 Amino acid transport and metabolism Carbamoylphosphate synthase small subunit SSO0641 good E COG0458 Amino acid transport and metabolism Carbamoylphosphate synthase large subunit (split gene in MJ) SSO0643 good E COG0458 Amino acid transport and metabolism Carbamoylphosphate synthase large subunit (split gene in MJ) SSO0645 good H COG0189 Coenzyme metabolism Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) SSO0646 good L COG2178 DNA replication, recombination and repair Translin (RNA-binding protein, recombination hotspot binding in eukaryotes) SSO0647 good I COG1250 Lipid metabolism 3-Hydroxyacyl-CoA dehydrogenase SSO0648 suspect: LH S COG1791 Function unknown Uncharacterized ACR, double-stranded beta-helix domain SSO0649 good S COG1814 Function unknown Uncharacterized membrane proteins SSO0651 good S COG1839 Function unknown Uncharacterized ACR SSO0653 good O COG1180 Posttranslational modification, protein turnover, chaperones Pyruvate-formate lyase-activating enzyme SSO0654 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO0656 good H COG0109 Coenzyme metabolism Polyprenyltransferase (cytochrome oxidase assembly factor) SSO0657 good E COG0460 Amino acid transport and metabolism Homoserine dehydrogenase SSO0659 good S COG0864 Function unknown Uncharacterized ACR, YhhG family SSO0660 good R COG0312 General function prediction only Predicted Zn-dependent proteases and their inactivated homologs SSO0661 suspect: %id R COG0312 General function prediction only Predicted Zn-dependent proteases and their inactivated homologs SSO0662 good H COG0340 Coenzyme metabolism Biotin-(acetyl-CoA carboxylase) ligase SSO0664 good J COG0009 Translation, ribosomal structure and biogenesis Putative translation factor (SUA5) SSO0665 good C COG0377 Energy production and conversion NADH:ubiquinone oxidoreductase 20 kD subunit NuoB/Nqo6/NdhK and related Fe-S oxidoreductases SSO0669 good R COG1321 General function prediction only Predicted iron-dependent transcription repressor SSO0673 normal R COG0500 General function prediction only SAM-dependent methyltransferases SSO0674 good R COG0517 General function prediction only CBS domains SSO0675 good H COG1763 Coenzyme metabolism Molybdopterin-guanine dinucleotide biosynthesis protein MobB SSO0676 good H COG0303 Coenzyme metabolism Molybdopterin biosynthesis enzyme SSO0677 suspect: LH H COG0746 Coenzyme metabolism Molybdopterin-guanine dinucleotide biosynthesis protein A SSO0678 good R COG2102 General function prediction only Predicted ATPases of PP-loop superfamily SSO0679 good F COG0402 Nucleotide transport and metabolism Cytosine deaminase and related metal-dependent hydrolases SSO0681 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO0683 suspect: HSP E COG0070 Amino acid transport and metabolism Glutamate synthetase domain 3 SSO0684 normal E COG0069 Amino acid transport and metabolism Glutamate synthetase domain 2 SSO0686 good R COG0577 General function prediction only Predicted permease SSO0687 suspect: LH S COG1361 Function unknown Predicted membrane protein SSO0688 check: MH R COG1136 General function prediction only ABC-type (unclassified) transport system, ATPase component SSO0689 good R COG1913 General function prediction only Predicted Zn-dependent proteases SSO0690 good S COG1371 Function unknown Uncharacterized ACR SSO0692 good F COG1102 Nucleotide transport and metabolism Cytidylate kinase 2 SSO0694 good F COG2019 Nucleotide transport and metabolism Archaeal adenylate kinase SSO0695 good N COG0201 Cell motility and secretion Preprotein translocase subunit SecY SSO0696 good J COG0200 Translation, ribosomal structure and biogenesis Ribosomal protein L15 SSO0697 good J COG1841 Translation, ribosomal structure and biogenesis Ribosomal protein L30/L7E SSO0698 good J COG0098 Translation, ribosomal structure and biogenesis Ribosomal protein S5 SSO0699 good J COG0256 Translation, ribosomal structure and biogenesis Ribosomal protein L18 SSO0700 good J COG2147 Translation, ribosomal structure and biogenesis Ribosomal protein L19E SSO0701 good J COG1717 Translation, ribosomal structure and biogenesis Ribosomal protein L32E SSO0702 good J COG0097 Translation, ribosomal structure and biogenesis Ribosomal protein L6 SSO0703 good J COG0096 Translation, ribosomal structure and biogenesis Ribosomal protein S8 SSO0704 good J COG0094 Translation, ribosomal structure and biogenesis Ribosomal protein L5 SSO0705 good J COG1471 Translation, ribosomal structure and biogenesis Ribosomal protein S4E SSO0707 good J COG0198 Translation, ribosomal structure and biogenesis Ribosomal protein L24 SSO0708 good J COG0093 Translation, ribosomal structure and biogenesis Ribosomal protein L14 SSO0709 good J COG0186 Translation, ribosomal structure and biogenesis Ribosomal protein S17 SSO0712 good J COG0092 Translation, ribosomal structure and biogenesis Ribosomal protein S3 SSO0713 good J COG0091 Translation, ribosomal structure and biogenesis Ribosomal protein L22 SSO0715 good J COG0185 Translation, ribosomal structure and biogenesis Ribosomal protein S19 SSO0716 good J COG0090 Translation, ribosomal structure and biogenesis Ribosomal protein L2 SSO0718 good J COG0088 Translation, ribosomal structure and biogenesis Ribosomal protein L4 SSO0719 good J COG0087 Translation, ribosomal structure and biogenesis Ribosomal protein L3 SSO0720 suspect: LH S COG2106 Function unknown Uncharacterized ACR SSO0722 good J COG0060 Translation, ribosomal structure and biogenesis Isoleucyl-tRNA synthetase SSO0723 good E COG0473 Amino acid transport and metabolism Isopropylmalate dehydrogenase SSO0726 good R COG1011 General function prediction only Predicted hydrolases of the HAD superfamily SSO0728 good J COG0480 Translation, ribosomal structure and biogenesis Translation elongation and release factors (GTPases) SSO0729 good L COG1948 DNA replication, recombination and repair ERCC4-type nucleases SSO0730 good S COG1382 Function unknown Uncharacterized ArCR SSO0731 suspect: LH S COG2136 Function unknown Uncharacterized ACR SSO0732 good L COG2123 DNA replication, recombination and repair Predicted nuclease related to RNase PH SSO0735 good J COG0689 Translation, ribosomal structure and biogenesis RNase PH SSO0736 good J COG1097 Translation, ribosomal structure and biogenesis Predicted RNA-binding proteins (S1 domain) SSO0737 good S COG1500 Function unknown Uncharacterized ACR SSO0738 good O COG0638 Posttranslational modification, protein turnover, chaperones Proteasome protease subunit HslV SSO0739 suspect: LH S COG1369 Function unknown Uncharacterized ACR SSO0741 good S COG1325 Function unknown Uncharacterized ArCR SSO0742 good J COG1632 Translation, ribosomal structure and biogenesis Ribosomal protein L15E SSO0743 good R COG0012 General function prediction only Predicted GTPase SSO0745 check: MH M COG1208 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis/translation and initiation factor eIF2B subunits SSO0746 good J COG1890 Translation, ribosomal structure and biogenesis Ribosomal protein S3AE SSO0747 good J COG0565 Translation, ribosomal structure and biogenesis rRNA methylase SSO0748 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0749 good J COG0030 Translation, ribosomal structure and biogenesis Dimethyladenosine transferase (rRNA methylation) SSO0750 good L COG1491 DNA replication, recombination and repair Predicted DNA-binding protein SSO0752 good J COG2139 Translation, ribosomal structure and biogenesis Ribosomal protein L21E SSO0755 good H COG0499 Coenzyme metabolism S-adenosylhomocysteine hydrolase SSO0757 good E COG0421 Amino acid transport and metabolism Spermidine synthase SSO0758 good O COG1047 Posttranslational modification, protein turnover, chaperones FKBP-type peptidyl-prolyl cis-trans isomerases 2 SSO0760 good C COG0371 Energy production and conversion Glycerol dehydrogenase SSO0761 good R COG1236 General function prediction only Predicted Zn-dependent hydrolases (beta-lactamase superfamily) SSO0764 check: MH C COG0604 Energy production and conversion NADPH:quinone reductase and related Zn-dependent oxidoreductases SSO0765 good J COG0154 Translation, ribosomal structure and biogenesis Glu-tRNAGln amidotransferase A subunit (amidase) SSO0766 good O COG0638 Posttranslational modification, protein turnover, chaperones Proteasome protease subunit HslV SSO0767 good S COG1881 Function unknown Uncharacterized ACR, YbhB family SSO0768 good L COG0470 DNA replication, recombination and repair ATPase involved in DNA replication SSO0769 good L COG0470 DNA replication, recombination and repair ATPase involved in DNA replication SSO0770 good H COG0315 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme SSO0771 good L COG1474 DNA replication, recombination and repair Cdc6-related protein, AAA superfamily ATPase SSO0774 good L COG1241 DNA replication, recombination and repair Predicted ATPase involved in replication control, Cdc46/Mcm family SSO0776 good I COG0575 Lipid metabolism CDP-diglyceride synthetase SSO0777 suspect: Pn L COG0468 DNA replication, recombination and repair RecA/RadA recombinase SSO0779 suspect: %id R COG1341 General function prediction only Predicted GTPase or GTP-binding protein SSO0780 good F COG0125 Nucleotide transport and metabolism Thymidylate kinase SSO0781 suspect: LH R COG1645 General function prediction only Uncharacterized Zn-finger containing protein SSO0782 suspect: LH L COG0582 DNA replication, recombination and repair Integrase SSO0786 suspect: LH E COG1113 Amino acid transport and metabolism Gamma-aminobutyrate and related permeases SSO0788 suspect: %id C COG0277 Energy production and conversion FAD/FMN-containing dehydrogenases SSO0790 good E COG0624 Amino acid transport and metabolism Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SSO0791 suspect: %id M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO0794 suspect: LH L COG0675 DNA replication, recombination and repair Predicted transposases SSO0797 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO0801 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO0809 good M COG0451 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar epimerases SSO0810 good M COG1004 Cell envelope biogenesis, outer membrane Predicted UDP-glucose 6-dehydrogenase SSO0813 good M COG1210 Cell envelope biogenesis, outer membrane UDP-glucose pyrophosphorylase SSO0814 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0818 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0819 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO0821 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0822 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO0829 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO0830 check: MH M COG1088 Cell envelope biogenesis, outer membrane dTDP-D-glucose 4,6-dehydratase SSO0831 check: MH M COG1209 Cell envelope biogenesis, outer membrane dTDP-glucose pyrophosphorylase SSO0832 good M COG1091 Cell envelope biogenesis, outer membrane dTDP-4-dehydrorhamnose reductase SSO0833 good M COG1898 Cell envelope biogenesis, outer membrane dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes SSO0842 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO0857 good J COG0018 Translation, ribosomal structure and biogenesis Arginyl-tRNA synthetase SSO0862 good O COG0459 Posttranslational modification, protein turnover, chaperones Chaperonin GroEL (HSP60 family) SSO0871 good E COG0078 Amino acid transport and metabolism Ornithine carbamoyltransferase SSO0872 good S COG1602 Function unknown Uncharacterized ACR SSO0873 good R COG0613 General function prediction only Predicted metal-dependent phosphoesterases (PHP family) SSO0874 good E COG0136 Amino acid transport and metabolism Aspartate-semialdehyde dehydrogenase SSO0876 good E COG0527 Amino acid transport and metabolism Aspartokinases SSO0878 good E COG0498 Amino acid transport and metabolism Threonine synthase SSO0879 good S COG0043 Function unknown Uncharacterized ACR, YigC family SSO0883 good G COG0574 Carbohydrate transport and metabolism Phosphoenolpyruvate synthase SSO0886 good I COG1260 Lipid metabolism Myo-inositol-1-phosphate synthase SSO0887 good C COG1254 Energy production and conversion Acylphosphatases SSO0888 check: MH R COG1350 General function prediction only Homologs of tryptophan synthase beta subunit SSO0889 suspect: %id E COG0159 Amino acid transport and metabolism Tryptophan synthase alpha chain SSO0890 good E COG0547 Amino acid transport and metabolism Anthranilate phosphoribosyltransferase SSO0892 suspect: %id E COG0135 Amino acid transport and metabolism Phosphoribosylanthranilate isomerase SSO0893 good E COG0147 Amino acid transport and metabolism Anthranilate/para-aminobenzoate synthases component II SSO0894 good E COG0512 Amino acid transport and metabolism Anthranilate/para-aminobenzoate synthases component I SSO0895 good E COG0134 Amino acid transport and metabolism Indole-3-glycerol phosphate synthase SSO0897 good E COG0436 Amino acid transport and metabolism PLP-dependent aminotransferases SSO0898 suspect: %id C COG0644 Energy production and conversion Dehydrogenases (flavoproteins) SSO0899 good J COG0525 Translation, ribosomal structure and biogenesis Valyl-tRNA synthetase SSO0904 good L COG1059 DNA replication, recombination and repair Endonuclease III-related proteins SSO0905 good E COG0111 Amino acid transport and metabolism Phosphoglycerate dehydrogenase SSO0906 good E COG0075 Amino acid transport and metabolism Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase SSO0907 good L COG0550 DNA replication, recombination and repair Topoisomerase IA SSO0909 good O COG0464 Posttranslational modification, protein turnover, chaperones AAA+ class ATPases SSO0911 suspect: LH R COG0845 General function prediction only Membrane permeases, predicted cation efflux pumps SSO0913 good G COG0148 Carbohydrate transport and metabolism Enolase SSO0916 good N COG0681 Cell motility and secretion Signal peptidase I SSO0917 good E COG1003 Amino acid transport and metabolism Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain SSO0918 good E COG0403 Amino acid transport and metabolism Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain SSO0919 good E COG0404 Amino acid transport and metabolism Glycine cleavage system T protein (aminomethyltransferase) SSO0920 good E COG0509 Amino acid transport and metabolism Glycine cleavage system H protein (lipoate-binding) SSO0921 good R COG1938 General function prediction only Archaeal enzymes of ATP-grasp superfamily SSO0923 good P COG0704 Inorganic ion transport and metabolism Phosphate uptake regulator SSO0925 check: MH R COG0396 General function prediction only Iron-regulated ABC transporter ATPase subunit SufC SSO0927 good R COG0719 General function prediction only Predicted membrane components of an uncharacterized iron-regulated ABC-type transporter SufB SSO0928 suspect: HSP R COG0719 General function prediction only Predicted membrane components of an uncharacterized iron-regulated ABC-type transporter SufB SSO0929 good F COG0209 Nucleotide transport and metabolism Ribonucleotide reductase alpha subunit SSO0936 good J COG0064 Translation, ribosomal structure and biogenesis Glu-tRNAGln amidotransferase B subunit (PET112 homolog) SSO0938 good E COG0252 Amino acid transport and metabolism L-asparaginase SSO0939 good J COG1498 Translation, ribosomal structure and biogenesis Protein implicated in ribosomal biogenesis, Nop56p homolog SSO0940 good J COG1889 Translation, ribosomal structure and biogenesis Fibrillarin-like rRNA methylase SSO0942 good K CKG1397 Transcription Predicted transcriptional regulators SSO0943 good J COG1867 Translation, ribosomal structure and biogenesis N2,N2-dimethylguanosine tRNA methyltransferase SSO0946 good K COG1405 Transcription Transcription initiation factor IIB SSO0947 suspect: %id S COG1340 Function unknown Uncharacterized archaeal coiled-coil domain SSO0949 good S COG2237 Function unknown Predicted membrane protein SSO0951 good K COG2101 Transcription Transcription initiation factor TFIID (TATA-binding protein) SSO0952 good R COG1407 General function prediction only Predicted ICC-like phosphoesterases SSO0953 good J COG1798 Translation, ribosomal structure and biogenesis Diphthamide biosynthesis methyltransferase DPH5 SSO0954 good R COG0615 General function prediction only Predicted cytidylyltransferases SSO0955 good S COG1339 Function unknown Uncharacterized ACR SSO0956 good C COG0731 Energy production and conversion Fe-S oxidoreductases SSO0957 good J COG0154 Translation, ribosomal structure and biogenesis Glu-tRNAGln amidotransferase A subunit (amidase) SSO0959 check: MH L COG1061 DNA replication, recombination and repair DNA or RNA helicases of superfamily II SSO0962 good S COG1581 Function unknown Uncharacterized ArCR SSO0963 check: MH L COG1110 DNA replication, recombination and repair Reverse gyrase SSO0965 check: MH R COG1201 General function prediction only Lhr-like helicases SSO0966 good S COG1690 Function unknown Uncharacterized ACR, RtcB/UPF0027 family SSO0967 good J COG1899 Translation, ribosomal structure and biogenesis Deoxyhypusine synthase SSO0968 good L COG1389 DNA replication, recombination and repair DNA topoisomerase VI, subunit B SSO0969 good L COG1697 DNA replication, recombination and repair DNA topoisomerase VI, subunit A SSO0970 good J COG0231 Translation, ribosomal structure and biogenesis Translation elongation factor P/translation initiation factor eIF5-a SSO0971 good N COG0541 Cell motility and secretion Signal recognition particle GTPase Ffh SSO0972 suspect: LH J COG1258 Translation, ribosomal structure and biogenesis Predicted pseudouridylate synthase SSO0974 good I COG2084 Lipid metabolism 3-hydroxyisobutyrate dehydrogenase and related proteins SSO0975 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO0976 good F COG0528 Nucleotide transport and metabolism Uridylate kinase SSO0977 good E COG0119 Amino acid transport and metabolism Isopropylmalate/homocitrate/citramalate synthases SSO0978 good G COG0120 Carbohydrate transport and metabolism Ribose 5-phosphate isomerase SSO0979 suspect: LH S COG2149 Function unknown Predicted membrane protein SSO0981 good G COG0469 Carbohydrate transport and metabolism Pyruvate kinase SSO0985 suspect: %id R COG0665 General function prediction only Predicted oxidoreductases SSO0987 check: MH G COG0297 Carbohydrate transport and metabolism Glycogen synthase SSO0988 suspect: LH G COG1449 Carbohydrate transport and metabolism Alpha-amylase/alpha-mannosidase SSO0989 good M COG1208 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis/translation and initiation factor eIF2B subunits SSO0991 suspect: LH G COG0366 Carbohydrate transport and metabolism Glycosidases SSO0992 suspect: LH G COG0477 Carbohydrate transport and metabolism Permeases SSO0996 good H COG0157 Coenzyme metabolism Nicotinate-nucleotide pyrophosphorylase SSO0997 check: MH H COG0029 Coenzyme metabolism Aspartate oxidase SSO0998 good H COG0379 Coenzyme metabolism Quinolinate synthase SSO0999 suspect: %id G COG1653 Carbohydrate transport and metabolism Sugar-binding periplasmic proteins/domains SSO1000 good G COG1175 Carbohydrate transport and metabolism ABC-type sugar transport systems, permease components SSO1001 suspect: %id G COG0395 Carbohydrate transport and metabolism Sugar permeases SSO1003 check: MH G COG1130 Carbohydrate transport and metabolism ABC-type sugar transport system, ATPase component SSO1004 suspect: %id C COG0277 Energy production and conversion FAD/FMN-containing dehydrogenases SSO1007 good E COG0624 Amino acid transport and metabolism Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SSO1009 suspect: %id E COG0833 Amino acid transport and metabolism Amino acid transporters SSO1010 good R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO1012 good E COG0028 Amino acid transport and metabolism Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] SSO1019 good P COG0607 Inorganic ion transport and metabolism Rhodanese-related sulfurtransferases SSO1021 good C COG0651 Energy production and conversion Formate hydrogenlyase subunit 3, HycC SSO1022 good C COG0377 Energy production and conversion NADH:ubiquinone oxidoreductase 20 kD subunit NuoB/Nqo6/NdhK and related Fe-S oxidoreductases SSO1023 good C COG0649 Energy production and conversion Formate hydrogenlyase subunit 5 and NADH-ubiquinone oxidoreductase 49 kD subunit 7 (chain D), NuoD/NQO4/Nad7 SSO1024 good C COG0651 Energy production and conversion Formate hydrogenlyase subunit 3, HycC SSO1026 good C COG0650 Energy production and conversion Formate hydrogenlyase subunit 4, HycD SSO1028 good R COG0084 General function prediction only Predicted hydrolases of PHP superfamily SSO1029 good C COG0243 Energy production and conversion Anaerobic dehydrogenases, typically selenocysteine-containing SSO1030 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO1031 good P COG0725 Inorganic ion transport and metabolism Molybdenum-binding periplasmic protein SSO1032 good E COG0555 Amino acid transport and metabolism ABC-type cysteine/molybdate transport systems, permease components SSO1034 check: MH R COG1136 General function prediction only ABC-type (unclassified) transport system, ATPase component SSO1038 suspect: LH S COG2112 Function unknown Uncharacterized ACR SSO1039 good J COG1746 Translation, ribosomal structure and biogenesis tRNA nucleotidyltransferase (CCA-adding enzyme) SSO1040 good J COG1514 Translation, ribosomal structure and biogenesis 2'-5' RNA ligase and related enzymes SSO1041 good F COG1616 Nucleotide transport and metabolism Predicted nucleotide kinases SSO1042 good S COG1931 Function unknown Uncharacterized ArCR SSO1043 good R COG1234 General function prediction only Metal-dependent hydrolases of the beta-lactamase superfamily III SSO1044 good L COG1041 DNA replication, recombination and repair Predicted DNA modification methylase SSO1045 good F COG0462 Nucleotide transport and metabolism Phosphoribosylpyrophosphate synthetase SSO1046 good R COG1100 General function prediction only GTPases SSO1047 good L COG0592 DNA replication, recombination and repair DNA polymerase III beta subunit SSO1048 good L COG1467 DNA replication, recombination and repair DNA primase, small subunit SSO1050 good J COG1093 Translation, ribosomal structure and biogenesis Translation initiation factor eIF2alpha SSO1052 suspect: %id S COG1287 Function unknown Uncharacterized membrane protein, required for N-linked glycosylation SSO1054 good P COG0004 Inorganic ion transport and metabolism Ammonia permeases SSO1060 good H COG0095 Coenzyme metabolism Lipoate-protein ligase A SSO1061 good E COG0509 Amino acid transport and metabolism Glycine cleavage system H protein (lipoate-binding) SSO1063 suspect: LH C COG0277 Energy production and conversion FAD/FMN-containing dehydrogenases SSO1064 good F COG0041 Nucleotide transport and metabolism Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase PurE SSO1065 good F COG0026 Nucleotide transport and metabolism Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) PurK SSO1066 suspect: LH R COG2005 General function prediction only N-terminal domain of molybdenum-binding protein ModE SSO1067 good R COG0693 General function prediction only Putative intracellular protease/amidase SSO1069 good E COG0531 Amino acid transport and metabolism Amino acid transporters SSO1072 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1074 suspect: LH O COG1651 Posttranslational modification, protein turnover, chaperones Protein-disulfide isomerases DsbC/DsbG SSO1075 good R COG0517 General function prediction only CBS domains SSO1077 good C COG0114 Energy production and conversion Fumarase SSO1078 check: MH R COG1136 General function prediction only ABC-type (unclassified) transport system, ATPase component SSO1080 good R COG0577 General function prediction only Predicted permease SSO1082 suspect: LH K COG1846 Transcription Transcriptional regulators, MarR/EmrR family SSO1083 good I COG1788 Lipid metabolism Acyl-CoA:acetate CoA transferase alpha subunit SSO1085 suspect: LH I COG2057 Lipid metabolism Coenzyme A transferases, subunit B SSO1088 suspect: LH S COG1716 Function unknown Uncharacterized BCR SSO1090 good T COG0639 Signal transduction mechanisms Diadenosine tetraphosphatase and related serine/threonine protein phosphatases SSO1093 suspect: LH J COG1530 Translation, ribosomal structure and biogenesis Ribonucleases G and E SSO1095 check: MH C COG1048 Energy production and conversion Aconitase A SSO1103 suspect: HSP G COG0477 Carbohydrate transport and metabolism Permeases SSO1105 good E COG0509 Amino acid transport and metabolism Glycine cleavage system H protein (lipoate-binding) SSO1110 suspect: LH K COG0640 Transcription Predicted transcriptional regulators SSO1111 good S COG1832 Function unknown Uncharacterized ACR SSO1112 good H COG0095 Coenzyme metabolism Lipoate-protein ligase A SSO1114 good S COG1856 Function unknown Uncharacterized ACR, biotin synthetase homolog SSO1115 good H COG1060 Coenzyme metabolism Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes SSO1117 good R COG0123 General function prediction only Deacetylases, including yeast histone deacetylase and acetoin utilization protein SSO1119 suspect: LH N COG1536 Cell motility and secretion Flagellar motor switch protein FliG SSO1120 good O COG0526 Posttranslational modification, protein turnover, chaperones Thiol-disulfide isomerase and thioredoxins SSO1123 good C COG1249 Energy production and conversion Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes SSO1125 good R COG2044 General function prediction only Predicted peroxiredoxins SSO1126 good S COG2210 Function unknown Uncharacterized ACR SSO1127 good C COG1150 Energy production and conversion Heterodisulfide reductase, subunit C SSO1129 good C COG2048 Energy production and conversion Heterodisulfide reductase subunit B SSO1131 good C COG1148 Energy production and conversion Polyferredoxins SSO1134 good C COG1150 Energy production and conversion Heterodisulfide reductase, subunit C SSO1135 good C COG2048 Energy production and conversion Heterodisulfide reductase subunit B SSO1138 suspect: %id P COG0475 Inorganic ion transport and metabolism K efflux system, membrane domain SSO1140 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO1142 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO1143 suspect: %id M COG1682 Cell envelope biogenesis, outer membrane Membrane permeases involved in cell wall biosynthesis SSO1144 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO1145 good R COG1350 General function prediction only Homologs of tryptophan synthase beta subunit SSO1146 suspect: Pn G COG0477 Carbohydrate transport and metabolism Permeases SSO1148 suspect: LH E COG1834 Amino acid transport and metabolism N-Dimethylarginine dimethylaminohydrolase SSO1151 good R COG0312 General function prediction only Predicted Zn-dependent proteases and their inactivated homologs SSO1152 good R COG0312 General function prediction only Predicted Zn-dependent proteases and their inactivated homologs SSO1153 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO1154 good E COG2030 Amino acid transport and metabolism Monoamine oxidase SSO1155 good R COG1373 General function prediction only Uncharacterized ATPases of the AAA superfamily SSO1156 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO1157 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO1159 suspect: LH R COG1011 General function prediction only Predicted hydrolases of the HAD superfamily SSO1160 suspect: LH R COG1708 General function prediction only Predicted nucleotidyltransferases SSO1161 suspect: LH S COG2250 Function unknown Uncharacterized ACR SSO1162 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1168 check: MH G COG1130 Carbohydrate transport and metabolism ABC-type sugar transport system, ATPase component SSO1169 good G COG0395 Carbohydrate transport and metabolism Sugar permeases SSO1170 good G COG1175 Carbohydrate transport and metabolism ABC-type sugar transport systems, permease components SSO1171 good G COG2182 Carbohydrate transport and metabolism Maltose-binding periplasmic proteins/domains SSO1172 suspect: HSP G COG1449 Carbohydrate transport and metabolism Alpha-amylase/alpha-mannosidase SSO1174 suspect: Pn P COG0530 Inorganic ion transport and metabolism Ca2+/Na+ antiporter SSO1176 good L COG1591 DNA replication, recombination and repair Holliday junction resolvase - archaeal type SSO1177 good E COG0436 Amino acid transport and metabolism PLP-dependent aminotransferases SSO1178 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO1182 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1183 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO1184 good R COG1335 General function prediction only Amidases related to nicotinamidase SSO1187 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1188 suspect: %id R COG1233 General function prediction only Phytoene dehydrogenase and related proteins SSO1189 good S COG2159 Function unknown Uncharacterized ACR, putative hydrolase SSO1191 suspect: %id F COG0125 Nucleotide transport and metabolism Thymidylate kinase SSO1192 good F COG0125 Nucleotide transport and metabolism Thymidylate kinase SSO1193 suspect: %id F COG0248 Nucleotide transport and metabolism Exopolyphosphatase SSO1194 good F COG0248 Nucleotide transport and metabolism Exopolyphosphatase SSO1195 good T COG2062 Signal transduction mechanisms Phosphohistidine phosphatase SixA SSO1196 good R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO1204 suspect: LH R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO1206 good C COG1013 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit SSO1207 good C COG0674 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit SSO1208 good C COG1014 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit SSO1209 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO1213 suspect: LH C COG0680 Energy production and conversion Hydrogenase formation/expression factor HyaD/HupD SSO1214 good P COG0288 Inorganic ion transport and metabolism Carbonic anhydrase SSO1216 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1218 good C COG1012 Energy production and conversion NAD-dependent aldehyde dehydrogenases SSO1220 check: MH C COG1062 Energy production and conversion Alcohol dehydrogenase class III and related dehydrogenases SSO1225 good R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO1230 suspect: LH P COG2146 Inorganic ion transport and metabolism Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases SSO1234 suspect: LH R COG2151 General function prediction only Putative aromatic ring hydroxylating enzyme SSO1251 good R COG1708 General function prediction only Predicted nucleotidyltransferases SSO1252 suspect: LH S COG2250 Function unknown Uncharacterized ACR SSO1253 suspect: LH R COG2050 General function prediction only Uncharacterized protein PaaI, possibly involved in aromatic compounds catabolism SSO1255 good K COG1802 Transcription Transcriptional regulators, GntR family SSO1256 suspect: %id L COG0419 DNA replication, recombination and repair ATPase involved in DNA repair SSO1258 good H COG1441 Coenzyme metabolism O-succinylbenzoate synthase and related enzymes SSO1261 suspect: LH R COG1611 General function prediction only Predicted Rossmann fold nucleotide-binding protein SSO1266 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO1268 good M COG0449 Cell envelope biogenesis, outer membrane Glucosamine-fructose-6-phosphate aminotransferase, contains aminotransferase and phosphosugar isomerase domains SSO1271 good J COG0013 Translation, ribosomal structure and biogenesis Alanyl-tRNA synthetase SSO1274 good E COG0601 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel permeases SSO1275 good E COG1173 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, permease components SSO1276 check: MH E COG0444 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO1277 check: MH E COG1124 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO1279 good E COG1124 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO1281 check: MH E COG1124 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO1282 check: MH E COG0444 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO1283 good E COG1173 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, permease components SSO1284 good E COG0601 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel permeases SSO1289 good R COG1373 General function prediction only Uncharacterized ATPases of the AAA superfamily SSO1292 suspect: LH S COG1975 Function unknown Uncharacterized BCR SSO1294 suspect: Pn D COG1192 Cell division and chromosome partitioning ATPases involved in chromosome partitioning SSO1299 good M COG1215 Cell envelope biogenesis, outer membrane Glycosyltransferases, probably involved in cell wall biogenesis SSO1300 good R COG1064 General function prediction only Zn-dependent alcohol dehydrogenases SSO1303 good H COG1441 Coenzyme metabolism O-succinylbenzoate synthase and related enzymes SSO1305 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1309 good E COG1305 Amino acid transport and metabolism Transglutaminase-like enzymes, putative cysteine proteases SSO1311 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO1314 good I COG0318 Lipid metabolism Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SSO1316 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1319 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO1322 good E COG0059 Amino acid transport and metabolism Ketol-acid reductoisomerase (isoleucine biosynthesis) SSO1324 suspect: LH H COG0422 Coenzyme metabolism Thiamine biosynthesis protein ThiC SSO1327 suspect: Pn R COG0433 General function prediction only Predicted ATPase SSO1328 normal L COG1401 DNA replication, recombination and repair McrB and related restriction endonucleases SSO1330 suspect: LH R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO1333 suspect: LH C COG2224 Energy production and conversion Isocitrate lyase SSO1334 normal C COG2225 Energy production and conversion Malate synthase SSO1336 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1338 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1340 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO1341 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1342 good I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO1343 good C COG1804 Energy production and conversion Predicted acyl-CoA transferases/carnitine dehydratase SSO1347 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1348 suspect: LH L COG0675 DNA replication, recombination and repair Predicted transposases SSO1351 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1352 good K COG1846 Transcription Transcriptional regulators, MarR/EmrR family SSO1355 good R COG1473 General function prediction only Metal-dependent amidohydrolases/aminoacylases SSO1357 suspect: %id M COG0463 Cell envelope biogenesis, outer membrane Glycosyltransferases involved in cell wall biogenesis SSO1361 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1368 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1369 good C COG1071 Energy production and conversion Thiamine pyrophosphate-dependent dehydrogenases, E1 component alpha subunit SSO1370 good C COG0022 Energy production and conversion Thiamine pyrophosphate-dependent dehydrogenases, E1 component beta subunit SSO1372 suspect: LH L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO1389 good S COG1517 Function unknown Uncharacterized ACR SSO1392 suspect: LH R COG1468 General function prediction only Predicted metal-binding, possibly nucleic acid-binding protein similar to domains found in Superfamily I helicases SSO1399 good S COG1857 Function unknown Uncharacterized ArCR SSO1402 good R COG1203 General function prediction only Predicted helicases SSO1403 suspect: LH S COG2254 Function unknown Uncharacterized ACR SSO1404 suspect: LH S COG1343 Function unknown Uncharacterized ACR SSO1405 good S COG1518 Function unknown Uncharacterized ACR SSO1418 good R COG1373 General function prediction only Uncharacterized ATPases of the AAA superfamily SSO1419 suspect: %id E COG1506 Amino acid transport and metabolism Dipeptidyl aminopeptidases/acylaminoacyl-peptidases SSO1425 good S COG1337 Function unknown Uncharacterized ACR SSO1436 suspect: LH L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO1439 suspect: LH S COG2254 Function unknown Uncharacterized ACR SSO1440 good R COG1203 General function prediction only Predicted helicases SSO1442 good S COG1857 Function unknown Uncharacterized ArCR SSO1449 suspect: LH R COG1468 General function prediction only Predicted metal-binding, possibly nucleic acid-binding protein similar to domains found in Superfamily I helicases SSO1450 suspect: %id S COG1518 Function unknown Uncharacterized ACR SSO1456 good L COG1112 DNA replication, recombination and repair Superfamily I DNA helicases and helicase subunits SSO1457 good E COG0334 Amino acid transport and metabolism Glutamate dehydrogenase/leucine dehydrogenase SSO1459 normal L COG0417 DNA replication, recombination and repair DNA-dependent DNA polymerase elongation subunit (family B) SSO1463 suspect: %id E COG0531 Amino acid transport and metabolism Amino acid transporters SSO1464 suspect: LH R COG1750 General function prediction only Archaeal serine proteases SSO1465 good O COG2039 Posttranslational modification, protein turnover, chaperones Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) SSO1468 good R COG1373 General function prediction only Uncharacterized ATPases of the AAA superfamily SSO1469 normal N COG0840 Cell motility and secretion Methyl-accepting chemotaxis protein SSO1471 good R COG1708 General function prediction only Predicted nucleotidyltransferases SSO1474 good L COG1943 DNA replication, recombination and repair Predicted transposase SSO1475 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1498 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1501 suspect: LH L COG0419 DNA replication, recombination and repair ATPase involved in DNA repair SSO1503 good O COG0225 Posttranslational modification, protein turnover, chaperones Peptide methionine sulfoxide reductase SSO1504 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1505 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1510 suspect: LH S COG1604 Function unknown Uncharacterized ACR SSO1514 suspect: %id S COG1336 Function unknown Uncharacterized ACR SSO1519 suspect: LH F COG0813 Nucleotide transport and metabolism Purine-nucleoside (and uridine) phosphorylase SSO1520 suspect: LH S COG2250 Function unknown Uncharacterized ACR SSO1524 good C COG1249 Energy production and conversion Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes SSO1525 good C COG1071 Energy production and conversion Thiamine pyrophosphate-dependent dehydrogenases, E1 component alpha subunit SSO1526 good C COG0022 Energy production and conversion Thiamine pyrophosphate-dependent dehydrogenases, E1 component beta subunit SSO1529 good C COG0508 Energy production and conversion Dihydrolipoamide acyltransferases SSO1530 good C COG0508 Energy production and conversion Dihydrolipoamide acyltransferases SSO1531 good C COG0277 Energy production and conversion FAD/FMN-containing dehydrogenases SSO1532 good C COG2141 Energy production and conversion Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases SSO1535 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO1537 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO1538 good E COG0624 Amino acid transport and metabolism Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SSO1539 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1542 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO1545 good R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO1552 good R COG0641 General function prediction only Arylsulfatase regulator (Fe-S oxidoreductase) SSO1560 good I COG2084 Lipid metabolism 3-hydroxyisobutyrate dehydrogenase and related proteins SSO1562 good R COG1373 General function prediction only Uncharacterized ATPases of the AAA superfamily SSO1563 suspect: LH R COG1373 General function prediction only Uncharacterized ATPases of the AAA superfamily SSO1565 good C COG1249 Energy production and conversion Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes SSO1566 good R COG0641 General function prediction only Arylsulfatase regulator (Fe-S oxidoreductase) SSO1567 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO1570 good S COG1917 Function unknown Uncharacterized ACR, double-stranded beta-helix domain SSO1577 suspect: %id C COG1145 Energy production and conversion Ferredoxin 2 SSO1579 good C COG0437 Energy production and conversion Fe-S-cluster-containing hydrogenase components 1 SSO1580 good C COG0243 Energy production and conversion Anaerobic dehydrogenases, typically selenocysteine-containing SSO1581 suspect: Pn C COG0348 Energy production and conversion Polyferredoxin SSO1589 good K COG1725 Transcription Predicted transcriptional regulators SSO1593 suspect: LH G COG0477 Carbohydrate transport and metabolism Permeases SSO1594 suspect: LH S COG1865 Function unknown Uncharacterized ACR SSO1595 good H COG1541 Coenzyme metabolism Coenzyme F390 synthetase SSO1597 check: MH H COG2228 Coenzyme metabolism o-Succinylbenzoate-CoA synthase SSO1598 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO1600 good C COG0554 Energy production and conversion Glycerol kinase SSO1601 good G COG0580 Carbohydrate transport and metabolism Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) SSO1605 suspect: LH R COG1768 General function prediction only Predicted phosphohydrolases SSO1606 suspect: Pn D COG1196 Cell division and chromosome partitioning Chromosome segregation ATPases SSO1607 good O COG2039 Posttranslational modification, protein turnover, chaperones Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) SSO1613 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO1614 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1618 suspect: HSP M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1619 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1620 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1621 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1622 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1623 normal R COG0500 General function prediction only SAM-dependent methyltransferases SSO1624 suspect: LH R COG0728 General function prediction only Uncharacterized membrane protein, putative virulence factor MviN SSO1626 suspect: %id M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1629 good C COG1012 Energy production and conversion NAD-dependent aldehyde dehydrogenases SSO1631 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO1632 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO1640 suspect: LH R COG1708 General function prediction only Predicted nucleotidyltransferases SSO1641 suspect: LH S COG2250 Function unknown Uncharacterized ACR SSO1646 good R COG1064 General function prediction only Zn-dependent alcohol dehydrogenases SSO1647 good E COG0028 Amino acid transport and metabolism Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] SSO1652 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1653 good K COG0553 Transcription Superfamily II DNA/RNA helicases, SNF2 family SSO1654 suspect: LH L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO1655 good K COG0553 Transcription Superfamily II DNA/RNA helicases, SNF2 family SSO1659 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1662 good E COG0146 Amino acid transport and metabolism N-methylhydaintoinase B SSO1663 good E COG0145 Amino acid transport and metabolism N-methylhydaintoinase A SSO1664 suspect: LH K COG1522 Transcription Transcriptional regulators, Lrp family SSO1665 suspect: %id F COG1953 Nucleotide transport and metabolism Cytosine/uracil/thiamine/allantoin permeases SSO1668 suspect: %id E COG0145 Amino acid transport and metabolism N-methylhydaintoinase A SSO1672 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1674 good S COG2250 Function unknown Uncharacterized ACR SSO1680 good R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO1681 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1682 suspect: Pn L COG0675 DNA replication, recombination and repair Predicted transposases SSO1683 suspect: LH L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO1693 suspect: %id E COG0531 Amino acid transport and metabolism Amino acid transporters SSO1726 suspect: %id S COG1336 Function unknown Uncharacterized ACR SSO1729 suspect: LH S COG1353 Function unknown Uncharacterized ACR, HD hydrolase domain with permuted motifs SSO1734 good M COG1088 Cell envelope biogenesis, outer membrane dTDP-D-glucose 4,6-dehydratase SSO1740 suspect: LH K COG1318 Transcription Predicted transcriptional regulators SSO1746 good T COG1848 Signal transduction mechanisms Archaeal proteins containing PIN domain SSO1752 suspect: %id R COG1418 General function prediction only Uncharacterized hydrolases of the HD superfamily SSO1755 good S COG2013 Function unknown Uncharacterized ACR SSO1757 suspect: %id P COG1226 Inorganic ion transport and metabolism Eukaryotic-type potassium channels SSO1759 suspect: LH O COG0826 Posttranslational modification, protein turnover, chaperones Protease related to collagenase SSO1777 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO1780 suspect: LH R COG0728 General function prediction only Uncharacterized membrane protein, putative virulence factor MviN SSO1781 check: MH M COG1088 Cell envelope biogenesis, outer membrane dTDP-D-glucose 4,6-dehydratase SSO1782 check: MH M COG1209 Cell envelope biogenesis, outer membrane dTDP-glucose pyrophosphorylase SSO1783 good M COG1091 Cell envelope biogenesis, outer membrane dTDP-4-dehydrorhamnose reductase SSO1785 normal M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO1787 good S COG1517 Function unknown Uncharacterized ACR SSO1806 good C COG1042 Energy production and conversion Acyl-CoA synthetases SSO1808 good H COG2226 Coenzyme metabolism Methylase involved in ubiquinone/menaquinone biosynthesis UbiE/COQ5 SSO1810 suspect: %id R COG0577 General function prediction only Predicted permease SSO1811 good R COG1228 General function prediction only Imidazolonepropionase and related amidohydrolases SSO1817 good P COG0607 Inorganic ion transport and metabolism Rhodanese-related sulfurtransferases SSO1818 check: MH L COG0419 DNA replication, recombination and repair ATPase involved in DNA repair SSO1824 good R COG1078 General function prediction only HD superfamily phosphohydrolases SSO1829 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1834 good S COG2250 Function unknown Uncharacterized ACR SSO1835 good R COG1708 General function prediction only Predicted nucleotidyltransferases SSO1839 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO1840 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO1842 good C COG1012 Energy production and conversion NAD-dependent aldehyde dehydrogenases SSO1844 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1857 good F COG0518 Nucleotide transport and metabolism GMP synthase - Glutamine amidotransferase domain SSO1859 good O COG0501 Posttranslational modification, protein turnover, chaperones Predicted Zn-dependent proteases (possible chaperone function) SSO1860 good S COG1968 Function unknown Uncharacterized ACR, bacitracin resistance protein BacA SSO1861 good T COG0467 Signal transduction mechanisms RecA-superfamily ATPases implicated in signal transduction SSO1863 suspect: LH G COG0477 Carbohydrate transport and metabolism Permeases SSO1865 good T COG0589 Signal transduction mechanisms Universal stress protein UspA and related nucleotide-binding proteins SSO1866 good R COG2151 General function prediction only Putative aromatic ring hydroxylating enzyme SSO1876 suspect: Pn K COG1522 Transcription Transcriptional regulators, Lrp family SSO1879 good L COG0513 DNA replication, recombination and repair Superfamily II DNA and RNA helicases SSO1880 suspect: LH R COG0697 General function prediction only Predicted permeases SSO1889 good L COG0513 DNA replication, recombination and repair Superfamily II DNA and RNA helicases SSO1892 suspect: LH P COG0619 Inorganic ion transport and metabolism Cobalt permease and related transporters SSO1893 check: MH P COG1122 Inorganic ion transport and metabolism ABC-type cobalt transport system, ATPase component SSO1896 good R COG1011 General function prediction only Predicted hydrolases of the HAD superfamily SSO1898 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO1900 good C COG1902 Energy production and conversion NADH:flavin oxidoreductases, Old Yellow Enzyme family SSO1901 normal R COG0500 General function prediction only SAM-dependent methyltransferases SSO1903 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO1905 good F COG1953 Nucleotide transport and metabolism Cytosine/uracil/thiamine/allantoin permeases SSO1906 good E COG0531 Amino acid transport and metabolism Amino acid transporters SSO1907 good E COG0334 Amino acid transport and metabolism Glutamate dehydrogenase/leucine dehydrogenase SSO1909 good G COG0477 Carbohydrate transport and metabolism Permeases SSO1916 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1918 good R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO1923 good M COG1898 Cell envelope biogenesis, outer membrane dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes SSO1930 good E COG0334 Amino acid transport and metabolism Glutamate dehydrogenase/leucine dehydrogenase SSO1934 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO1936 suspect: %id S COG1277 Function unknown Predicted membrane protein SSO1939 good R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO1941 good H COG0422 Coenzyme metabolism Thiamine biosynthesis protein ThiC SSO1942 good E COG0059 Amino acid transport and metabolism Ketol-acid reductoisomerase (isoleucine biosynthesis) SSO1952 good R COG1473 General function prediction only Metal-dependent amidohydrolases/aminoacylases SSO1954 good M COG0463 Cell envelope biogenesis, outer membrane Glycosyltransferases involved in cell wall biogenesis SSO1958 suspect: LH G COG0477 Carbohydrate transport and metabolism Permeases SSO1963 suspect: LH R COG1373 General function prediction only Uncharacterized ATPases of the AAA superfamily SSO1967 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO1968 good T COG1848 Signal transduction mechanisms Archaeal proteins containing PIN domain SSO1974 normal L COG0675 DNA replication, recombination and repair Predicted transposases SSO1975 suspect: Pn S COG1487 Function unknown Uncharacterized proteins, VapC family SSO1976 good S COG0393 Function unknown Uncharacterized ACR, MJ1170 family SSO1987 suspect: LH S COG1336 Function unknown Uncharacterized ACR SSO1990 suspect: %id S COG1604 Function unknown Uncharacterized ACR SSO1991 suspect: %id S COG1353 Function unknown Uncharacterized ACR, HD hydrolase domain with permuted motifs SSO1994 good R COG1106 General function prediction only Predicted ATPases SSO1997 good S COG1857 Function unknown Uncharacterized ArCR SSO1999 good R COG1203 General function prediction only Predicted helicases SSO2001 suspect: LH S COG2254 Function unknown Uncharacterized ACR SSO2008 good E COG0145 Amino acid transport and metabolism N-methylhydaintoinase A SSO2010 good E COG0146 Amino acid transport and metabolism N-methylhydaintoinase B SSO2015 suspect: %id O COG0826 Posttranslational modification, protein turnover, chaperones Protease related to collagenase SSO2017 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO2020 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO2021 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO2025 good C COG1902 Energy production and conversion NADH:flavin oxidoreductases, Old Yellow Enzyme family SSO2027 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO2028 good R COG1011 General function prediction only Predicted hydrolases of the HAD superfamily SSO2030 check: MH P COG1122 Inorganic ion transport and metabolism ABC-type cobalt transport system, ATPase component SSO2031 normal P COG0619 Inorganic ion transport and metabolism Cobalt permease and related transporters SSO2036 good L COG0513 DNA replication, recombination and repair Superfamily II DNA and RNA helicases SSO2039 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2040 good R COG1228 General function prediction only Imidazolonepropionase and related amidohydrolases SSO2041 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO2042 good F COG1953 Nucleotide transport and metabolism Cytosine/uracil/thiamine/allantoin permeases SSO2043 good E COG0531 Amino acid transport and metabolism Amino acid transporters SSO2044 good E COG0334 Amino acid transport and metabolism Glutamate dehydrogenase/leucine dehydrogenase SSO2047 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2055 good R COG1853 General function prediction only Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family SSO2057 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO2059 good I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO2060 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO2061 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2062 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2063 good S COG1545 Function unknown Uncharacterized ACR SSO2064 good S COG1545 Function unknown Uncharacterized ACR SSO2067 normal C COG0674 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit SSO2069 normal C COG1014 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit SSO2070 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO2071 good O COG1225 Posttranslational modification, protein turnover, chaperones Peroxiredoxins SSO2072 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO2073 good K COG1378 Transcription Predicted transcriptional regulators SSO2074 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO2078 suspect: HSP P COG1914 Inorganic ion transport and metabolism Putative Mn transporter, NRAMP family SSO2080 suspect: LH P COG2146 Inorganic ion transport and metabolism Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases SSO2085 suspect: HSP R COG2129 General function prediction only Predicted phosphoesterases, related to the Icc protein SSO2087 good R COG0412 General function prediction only Dienelactone hydrolase and related enzymes SSO2091 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO2093 check: MH G COG0296 Carbohydrate transport and metabolism 1,4-alpha-glucan branching enzyme SSO2094 good G COG1523 Carbohydrate transport and metabolism Pullulanase and related glycosidases SSO2095 good G COG0366 Carbohydrate transport and metabolism Glycosidases SSO2096 suspect: LH S COG1487 Function unknown Uncharacterized proteins, VapC family SSO2097 good H COG1985 Coenzyme metabolism Pyrimidine reductase, riboflavin biosynthesis SSO2098 suspect: LH M COG0793 Cell envelope biogenesis, outer membrane Periplasmic protease SSO2101 suspect: %id R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO2106 suspect: LH S COG2250 Function unknown Uncharacterized ACR SSO2111 suspect: LH G COG0477 Carbohydrate transport and metabolism Permeases SSO2112 good S COG2159 Function unknown Uncharacterized ACR, putative hydrolase SSO2113 good E COG0591 Amino acid transport and metabolism Na+/proline, Na+/panthothenate symporters and related permeases SSO2114 suspect: LH K COG1846 Transcription Transcriptional regulators, MarR/EmrR family SSO2116 check: MH P COG1122 Inorganic ion transport and metabolism ABC-type cobalt transport system, ATPase component SSO2119 suspect: HSP E COG1305 Amino acid transport and metabolism Transglutaminase-like enzymes, putative cysteine proteases SSO2121 good O COG0450 Posttranslational modification, protein turnover, chaperones Thiol - alkyl hydroperoxide reductases SSO2122 good J COG0154 Translation, ribosomal structure and biogenesis Glu-tRNAGln amidotransferase A subunit (amidase) SSO2123 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO2124 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO2126 good C COG1620 Energy production and conversion L-lactate permease SSO2127 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2128 suspect: HSP C COG1144 Energy production and conversion Ferredoxin-like subunits of formate hydrogenlyase SSO2129 good C COG0674 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit SSO2130 good C COG1013 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit SSO2131 good K COG1522 Transcription Transcriptional regulators, Lrp family SSO2133 good C COG0554 Energy production and conversion Glycerol kinase SSO2134 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2135 good S COG0842 Function unknown Predicted integral membrane protein SSO2137 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO2138 suspect: Pn K COG1695 Transcription Predicted transcriptional regulators SSO2139 good R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO2140 suspect: LH R COG2050 General function prediction only Uncharacterized protein PaaI, possibly involved in aromatic compounds catabolism SSO2141 good E COG1506 Amino acid transport and metabolism Dipeptidyl aminopeptidases/acylaminoacyl-peptidases SSO2143 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO2150 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO2151 good P COG0607 Inorganic ion transport and metabolism Rhodanese-related sulfurtransferases SSO2154 good E COG0308 Amino acid transport and metabolism Aminopeptidase N SSO2156 good L COG0648 DNA replication, recombination and repair Endonuclease IV SSO2157 suspect: HSP R COG0561 General function prediction only Predicted hydrolases of the HAD superfamily SSO2158 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO2159 good R COG1011 General function prediction only Predicted hydrolases of the HAD superfamily SSO2161 good M COG1091 Cell envelope biogenesis, outer membrane dTDP-4-dehydrorhamnose reductase SSO2162 normal C COG0277 Energy production and conversion FAD/FMN-containing dehydrogenases SSO2163 good F COG0537 Nucleotide transport and metabolism Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases SSO2167 good L COG0494 DNA replication, recombination and repair NTP pyrophosphohydrolases (MutT family) including oxidative damage repair enzymes SSO2171 good R COG1618 General function prediction only Predicted ATPases or kinases SSO2172 good H COG0171 Coenzyme metabolism NAD synthase SSO2174 good R COG0388 General function prediction only Predicted amidohydrolase SSO2177 suspect: %id R COG0500 General function prediction only SAM-dependent methyltransferases SSO2178 good E COG0136 Amino acid transport and metabolism Aspartate-semialdehyde dehydrogenase SSO2182 good C COG0538 Energy production and conversion Isocitrate dehydrogenases SSO2184 good L COG1474 DNA replication, recombination and repair Cdc6-related protein, AAA superfamily ATPase SSO2187 good H COG2154 Coenzyme metabolism Pterin-4a-carbinolamine dehydratase SSO2191 good R COG0457 General function prediction only TPR-repeat-containing proteins SSO2192 normal S COG2105 Function unknown Uncharacterized ACR, YkqA family SSO2193 suspect: LH S COG1585 Function unknown Uncharacterized ACR SSO2195 good O COG0330 Posttranslational modification, protein turnover, chaperones Membrane protease subunits, stomatin/prohibitin homologs SSO2199 suspect: LH L COG0419 DNA replication, recombination and repair ATPase involved in DNA repair SSO2200 suspect: %id R COG0433 General function prediction only Predicted ATPase SSO2201 normal J COG1549 Translation, ribosomal structure and biogenesis Queuine tRNA-ribosyltransferases, contain PUA domain SSO2204 good R COG1331 General function prediction only Highly conserved protein containing a thioredoxin domain SSO2205 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO2206 good K COG0819 Transcription Putative transcription activator SSO2208 good S COG1637 Function unknown Uncharacterized ACR SSO2209 suspect: LH M COG0463 Cell envelope biogenesis, outer membrane Glycosyltransferases involved in cell wall biogenesis SSO2211 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO2213 good H COG2038 Coenzyme metabolism NaMN:DMB phosphoribosyltransferase (cobalamin biosynthesis enzyme CobT) SSO2215 good E COG0520 Amino acid transport and metabolism Selenocysteine lyase SSO2216 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO2218 good J COG1439 Translation, ribosomal structure and biogenesis Ribosomal protein S15A SSO2219 good R COG0061 General function prediction only Predicted kinase SSO2220 suspect: Pn G COG0477 Carbohydrate transport and metabolism Permeases SSO2222 good O COG0492 Posttranslational modification, protein turnover, chaperones Thioredoxin reductase/alkyl hydroperoxide reductase SSO2223 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO2224 good S COG2090 Function unknown Uncharacterized ArCR SSO2225 good R COG2023 General function prediction only Uncharacterized archaeal Zn-finger domain SSO2226 good S COG1756 Function unknown Uncharacterized ACR, Mra1/C2f family SSO2228 suspect: %id P COG0053 Inorganic ion transport and metabolism Predicted Co/Zn/Cd cation transporters SSO2229 suspect: %id S COG2107 Function unknown Uncharacterized ACR SSO2230 good S COG1986 Function unknown Uncharacterized ACR SSO2232 suspect: LH O COG0526 Posttranslational modification, protein turnover, chaperones Thiol-disulfide isomerase and thioredoxins SSO2233 suspect: LH R COG0665 General function prediction only Predicted oxidoreductases SSO2234 good S COG1650 Function unknown Uncharacterized ArCR SSO2236 good G COG0406 Carbohydrate transport and metabolism Phosphoglycerate mutase/fructose-2,6-bisphosphatase SSO2237 suspect: LH R COG2129 General function prediction only Predicted phosphoesterases, related to the Icc protein SSO2241 suspect: HSP L COG0419 DNA replication, recombination and repair ATPase involved in DNA repair SSO2243 good F COG1957 Nucleotide transport and metabolism Inosine-uridine nucleoside N-ribohydrolase SSO2244 good P COG0735 Inorganic ion transport and metabolism Ferric uptake regulation protein SSO2246 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO2247 suspect: %id P COG1230 Inorganic ion transport and metabolism Co/Zn/Cd efflux system component SSO2248 suspect: LH S COG1630 Function unknown Uncharacterized ArCR SSO2249 suspect: %id L COG0419 DNA replication, recombination and repair ATPase involved in DNA repair SSO2250 suspect: LH L COG0420 DNA replication, recombination and repair DNA repair exonuclease SSO2251 good R COG0433 General function prediction only Predicted ATPase SSO2254 good G COG0063 Carbohydrate transport and metabolism Predicted sugar kinase SSO2255 good O COG1225 Posttranslational modification, protein turnover, chaperones Peroxiredoxins SSO2256 good S COG1892 Function unknown Uncharacterized ArCR SSO2261 suspect: LH R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO2262 good R COG0596 General function prediction only Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) SSO2265 suspect: LH E COG1703 Amino acid transport and metabolism ArgK, kinase of periplasmic Arg,Orn-binding proteins SSO2266 good I COG2185 Lipid metabolism Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) SSO2272 suspect: LH R COG0730 General function prediction only Predicted permeases SSO2273 good R COG1321 General function prediction only Predicted iron-dependent transcription repressor SSO2274 suspect: LH E COG0329 Amino acid transport and metabolism Dihydrodipicolinate synthetase/N-acetylneuraminate lyase SSO2275 good L COG1573 DNA replication, recombination and repair Uracil-DNA glycosylase SSO2276 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO2277 good R COG1106 General function prediction only Predicted ATPases SSO2278 good F COG1051 Nucleotide transport and metabolism ADP-ribose pyrophosphatase SSO2280 good J COG0215 Translation, ribosomal structure and biogenesis Cysteinyl-tRNA synthetase SSO2281 suspect: LH G COG0166 Carbohydrate transport and metabolism Glucose-6-phosphate isomerase SSO2283 suspect: LH R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO2287 suspect: HSP I COG1607 Lipid metabolism Acyl-CoA hydrolase SSO2289 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO2290 good L COG0708 DNA replication, recombination and repair Exonuclease III SSO2291 suspect: HSP T COG0515 Signal transduction mechanisms Serine/threonine protein kinases SSO2295 suspect: LH R COG0824 General function prediction only Predicted esterase SSO2296 check: MH H COG2241 Coenzyme metabolism Precorrin-6B methylase 1 CobL1/CbiE SSO2297 good H COG2073 Coenzyme metabolism Cobalamin biosynthesis protein CbiG SSO2299 good H COG0007 Coenzyme metabolism Uroporphyrinogen-III methylase SSO2301 check: MH H COG2243 Coenzyme metabolism Precorrin-2 methylase CobI/CbiL SSO2303 check: MH H COG2242 Coenzyme metabolism Precorrin-6B methylase 2 CobL2/CbiT SSO2305 good H COG1903 Coenzyme metabolism Cobalamin biosynthesis protein CbiD SSO2306 check: MH H COG1010 Coenzyme metabolism Precorrin-3B methylase CobJ/CbiH SSO2308 good H COG2082 Coenzyme metabolism Precorrin isomerase SSO2309 good H COG0535 Coenzyme metabolism Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases SSO2310 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO2315 suspect: %id S COG1955 Function unknown Uncharacterized family of membrane proteins SSO2316 good N COG0630 Cell motility and secretion Predicted ATPases involved in pili biogenesis SSO2318 good T COG0467 Signal transduction mechanisms RecA-superfamily ATPases implicated in signal transduction SSO2320 suspect: LH L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO2323 suspect: LH N COG1681 Cell motility and secretion Flagellin SSO2331 suspect: Pn D COG1192 Cell division and chromosome partitioning ATPases involved in chromosome partitioning SSO2332 suspect: LH D COG0455 Cell division and chromosome partitioning ATPases involved in chromosome partitioning SSO2334 check: MH C COG0604 Energy production and conversion NADPH:quinone reductase and related Zn-dependent oxidoreductases SSO2339 good J COG1503 Translation, ribosomal structure and biogenesis Peptide chain release factor eRF, subunit 1 SSO2342 good R COG2236 General function prediction only Predicted phosphoribosyltransferases SSO2343 good F COG0005 Nucleotide transport and metabolism Purine nucleoside phosphorylase SSO2345 good H COG0142 Coenzyme metabolism Geranylgeranyl pyrophosphate synthase SSO2346 good H COG0189 Coenzyme metabolism Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) SSO2347 good K COG1522 Transcription Transcriptional regulators, Lrp family SSO2348 suspect: %id C COG0644 Energy production and conversion Dehydrogenases (flavoproteins) SSO2350 good E COG1446 Amino acid transport and metabolism Asparaginase SSO2353 good C COG0644 Energy production and conversion Dehydrogenases (flavoproteins) SSO2355 good G COG0647 Carbohydrate transport and metabolism Predicted sugar phosphatases of the HAD superfamily SSO2356 good C COG1053 Energy production and conversion Succinate dehydrogenase/fumarate reductase, flavoprotein subunits SSO2357 good C COG0479 Energy production and conversion Succinate dehydrogenase/fumarate reductase Fe-S protein SSO2358 good C COG2048 Energy production and conversion Heterodisulfide reductase subunit B SSO2363 suspect: LH R COG0714 General function prediction only MoxR-like ATPases SSO2364 suspect: LH L COG1599 DNA replication, recombination and repair Predicted single-stranded DNA binding protein (homolog of replication factor A large subunit) SSO2365 good H COG0303 Coenzyme metabolism Molybdopterin biosynthesis enzyme SSO2367 good E COG0083 Amino acid transport and metabolism Homoserine kinase SSO2368 suspect: LH E COG0626 Amino acid transport and metabolism Cystathionine beta-lyases/cystathionine gamma-synthases SSO2373 good J COG1094 Translation, ribosomal structure and biogenesis Predicted RNA-binding proteins (consist of S1 domain and KH domain) SSO2374 suspect: LH T COG1718 Signal transduction mechanisms Predicted serine/threonine protein kinases SSO2375 good J COG0361 Translation, ribosomal structure and biogenesis Translation initiation factor IF-1 SSO2377 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2380 suspect: LH C COG0621 Energy production and conversion Fe-S oxidoreductases family 1 SSO2381 good J COG1601 Translation, ribosomal structure and biogenesis Translation initiation factor eIF-2, beta subunit/eIF-5 N-terminal domain SSO2383 good K COG1499 Transcription NMD protein affecting ribosome stability and mRNA decay SSO2384 suspect: LH L COG0164 DNA replication, recombination and repair Ribonuclease HII SSO2385 good R COG1163 General function prediction only Predicted GTPase SSO2386 suspect: LH S COG2064 Function unknown Uncharacterized membrane proteins SSO2387 good N COG0630 Cell motility and secretion Predicted ATPases involved in pili biogenesis SSO2389 check: MH M COG0463 Cell envelope biogenesis, outer membrane Glycosyltransferases involved in cell wall biogenesis SSO2390 good C COG0221 Energy production and conversion Inorganic pyrophosphatase SSO2391 good S COG1896 Function unknown Uncharacterized ACR SSO2393 good H COG0351 Coenzyme metabolism Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase SSO2394 normal H COG0314 Coenzyme metabolism Molybdopterin converting factor, large subunit SSO2397 good R COG1829 General function prediction only Predicted archaeal kinases of the sugar kinase superfamily SSO2398 suspect: LH C COG0247 Energy production and conversion Fe-S oxidoreductases SSO2399 good S COG1701 Function unknown Uncharacterized ArCR SSO2400 good H COG0413 Coenzyme metabolism Ketopantoate hydroxymethyltransferase SSO2402 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO2404 suspect: LH C COG1668 Energy production and conversion ATP-dependent Na+ efflux pump membrane component NatB SSO2406 good R COG2220 General function prediction only Predicted Zn-dependent hydrolases of the beta-lactamase fold SSO2407 good E COG0119 Amino acid transport and metabolism Isopropylmalate/homocitrate/citramalate synthases SSO2408 good S COG1634 Function unknown Uncharacterized ArCR SSO2412 normal H COG0720 Coenzyme metabolism 6-pyruvoyl-tetrahydropterin synthase SSO2415 good H COG0294 Coenzyme metabolism Dihydropteroate synthase SSO2416 good O COG0492 Posttranslational modification, protein turnover, chaperones Thioredoxin reductase/alkyl hydroperoxide reductase SSO2418 good G COG0483 Carbohydrate transport and metabolism Inositol phosphatase family proteins SSO2420 good O COG0464 Posttranslational modification, protein turnover, chaperones AAA+ class ATPases SSO2422 good R COG1233 General function prediction only Phytoene dehydrogenase and related proteins SSO2423 suspect: LH R COG1524 General function prediction only Uncharacterized proteins of the AP superfamily SSO2424 good R COG2236 General function prediction only Predicted phosphoribosyltransferases SSO2425 good I COG1884 Lipid metabolism Methylmalonyl-CoA mutase, N-terminal domain/subunit SSO2426 good E COG0346 Amino acid transport and metabolism Lactoylglutathione lyase SSO2427 good O COG0071 Posttranslational modification, protein turnover, chaperones Molecular chaperone (small heat shock protein) SSO2428 good R COG1779 General function prediction only C4-type Zn finger family SSO2429 good J COG0050 Translation, ribosomal structure and biogenesis GTPases - translation elongation factors and sulfate adenylate transferase subunit 1 SSO2432 good H COG0746 Coenzyme metabolism Molybdopterin-guanine dinucleotide biosynthesis protein A SSO2433 good C COG2080 Energy production and conversion Predicted aldehyde dehydrogenases SSO2434 good R COG1319 General function prediction only FeS-containing oxidoreductases, xanthine dehydrogenase homologs SSO2435 good H COG0007 Coenzyme metabolism Uroporphyrinogen-III methylase suspect: %id F COG0402 Nucleotide transport and metabolism Cytosine deaminase and related metal-dependent hydrolases SSO2439 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO2440 good E COG0174 Amino acid transport and metabolism Glutamine synthase SSO2441 good E COG1063 Amino acid transport and metabolism Threonine dehydrogenase and related Zn-dependent dehydrogenases SSO2446 good K COG0430 Transcription RNA phosphate cyclase SSO2448 good L COG0389 DNA replication, recombination and repair Nucleotidyltransferase/DNA polymerase involved in DNA repair SSO2449 suspect: %id G COG0524 Carbohydrate transport and metabolism Sugar kinases, ribokinase family SSO2450 check: MH L COG1224 DNA replication, recombination and repair DNA helicase TIP49, TBP-interacting protein SSO2451 good F COG0518 Nucleotide transport and metabolism GMP synthase - Glutamine amidotransferase domain SSO2452 good T COG0467 Signal transduction mechanisms RecA-superfamily ATPases implicated in signal transduction SSO2454 good L COG1515 DNA replication, recombination and repair Deoxyinosine 3'endonuclease (endonuclease V) SSO2455 good R COG1335 General function prediction only Amidases related to nicotinamidase SSO2458 suspect: LH R COG1409 General function prediction only Predicted phosphohydrolases, Icc family SSO2459 good S COG1415 Function unknown Uncharacterized ACR SSO2460 good S COG1392 Function unknown Uncharacterized ACR SSO2461 suspect: %id P COG0306 Inorganic ion transport and metabolism Phosphate permease SSO2462 check: MH R COG1204 General function prediction only Predicted helicases SSO2463 normal I COG0777 Lipid metabolism Acetyl-CoA carboxylase beta subunit SSO2464 good I COG0511 Lipid metabolism Biotin carboxyl carrier protein of acetyl-CoA carboxylase SSO2466 good I COG0439 Lipid metabolism Biotin carboxylase SSO2468 suspect: HSP R COG0600 General function prediction only Uncharacterized permeases SSO2469 check: MH P COG1116 Inorganic ion transport and metabolism ABC-type nitrate transport system, ATPase component SSO2470 good E COG0066 Amino acid transport and metabolism 3-isopropylmalate dehydratase small subunit SSO2471 good E COG0065 Amino acid transport and metabolism 3-Isopropylmalate dehydratase large subunit SSO2472 good L COG0415 DNA replication, recombination and repair Deoxypyrimidine photolyase SSO2476 good E COG0591 Amino acid transport and metabolism Na+/proline, Na+/panthothenate symporters and related permeases SSO2478 good H COG0846 Coenzyme metabolism Putative NaMN:DMB phosphoribosyltransferase (CobB)/SIR2 transcriptional regulator SSO2479 good M COG1208 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis/translation and initiation factor eIF2B subunits SSO2482 good C COG0074 Energy production and conversion Succinyl-CoA synthetase, alpha subunit SSO2483 good C COG0045 Energy production and conversion Succinyl-CoA synthetase beta chain SSO2484 check: MH L COG2231 DNA replication, recombination and repair Endonuclease III related proteins SSO2485 suspect: LH M COG0707 Cell envelope biogenesis, outer membrane UDP-glucuronosyltransferases SSO2486 good J COG0441 Translation, ribosomal structure and biogenesis Threonyl-tRNA synthetase SSO2487 good L COG0350 DNA replication, recombination and repair Methylated DNA-protein cysteine methyltransferase SSO2490 suspect: %id C COG1454 Energy production and conversion Alcohol dehydrogenase IV SSO2493 good I COG0657 Lipid metabolism Acetyl esterase SSO2494 check: MH C COG0604 Energy production and conversion NADPH:quinone reductase and related Zn-dependent oxidoreductases SSO2496 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2497 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO2498 good F COG0208 Nucleotide transport and metabolism Ribonucleotide reductase beta subunit SSO2500 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO2501 check: MH C COG1062 Energy production and conversion Alcohol dehydrogenase class III and related dehydrogenases SSO2505 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2506 good K COG1309 Transcription Transcriptional regulators, AcrR family SSO2508 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2509 suspect: Pn S COG1545 Function unknown Uncharacterized ACR SSO2510 good I COG0318 Lipid metabolism Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SSO2511 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO2514 good I COG1250 Lipid metabolism 3-Hydroxyacyl-CoA dehydrogenase SSO2515 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO2516 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2517 good I COG0657 Lipid metabolism Acetyl esterase SSO2519 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO2520 good R COG0179 General function prediction only 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) SSO2521 good I COG0657 Lipid metabolism Acetyl esterase SSO2522 suspect: LH R COG1735 General function prediction only Phosphotriesterase homology protein PHP/1bf6A (activity unknown) SSO2523 good I COG0318 Lipid metabolism Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SSO2526 good C COG0578 Energy production and conversion Anaerobic glycerol-3-phosphate dehydrogenase SSO2527 good R COG1228 General function prediction only Imidazolonepropionase and related amidohydrolases SSO2528 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2530 good S COG2250 Function unknown Uncharacterized ACR SSO2531 suspect: LH R COG1768 General function prediction only Predicted phosphohydrolases SSO2532 good S COG0432 Function unknown Uncharacterized ACR, YjbQ/UPF0047 family SSO2535 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO2536 good R COG1064 General function prediction only Zn-dependent alcohol dehydrogenases SSO2537 good C COG1274 Energy production and conversion Phosphoenolpyruvate carboxykinase SSO2538 suspect: %id G COG0058 Carbohydrate transport and metabolism Glucan phosphorylase SSO2553 suspect: LH S COG2159 Function unknown Uncharacterized ACR, putative hydrolase SSO2554 good E COG0174 Amino acid transport and metabolism Glutamine synthase SSO2558 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2559 good C COG1249 Energy production and conversion Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes SSO2560 good C COG0778 Energy production and conversion Nitroreductase family proteins SSO2568 good S COG1814 Function unknown Uncharacterized membrane proteins SSO2571 good G COG1489 Carbohydrate transport and metabolism Sugar fermentation stimulation protein (uncharacterized) SSO2574 suspect: Pn C COG1145 Energy production and conversion Ferredoxin 2 SSO2575 suspect: LH O COG0265 Posttranslational modification, protein turnover, chaperones Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain SSO2581 suspect: Pn K COG1522 Transcription Transcriptional regulators, Lrp family SSO2583 good M COG0451 Cell envelope biogenesis, outer membrane Nucleoside-diphosphate-sugar epimerases SSO2585 good C COG0039 Energy production and conversion Malate/lactate dehydrogenases SSO2586 good R COG2079 General function prediction only Uncharacterized protein involved in propionate catabolism SSO2587 good C COG2224 Energy production and conversion Isocitrate lyase SSO2588 good R COG0517 General function prediction only CBS domains SSO2589 good C COG0372 Energy production and conversion Citrate synthase SSO2592 good G COG0149 Carbohydrate transport and metabolism Triosephosphate isomerase SSO2595 good S COG1673 Function unknown Uncharacterized ArCR SSO2597 good E COG0075 Amino acid transport and metabolism Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase SSO2598 good K COG0819 Transcription Putative transcription activator SSO2599 good R COG0500 General function prediction only SAM-dependent methyltransferases SSO2600 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO2603 good O COG0071 Posttranslational modification, protein turnover, chaperones Molecular chaperone (small heat shock protein) SSO2605 good R COG0661 General function prediction only Predicted unusual protein kinase SSO2609 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO2612 good O COG0265 Posttranslational modification, protein turnover, chaperones Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain SSO2613 good O COG1225 Posttranslational modification, protein turnover, chaperones Peroxiredoxins SSO2615 check: MH E COG1124 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO2616 check: MH E COG0444 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO2617 good E COG1173 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, permease components SSO2618 good E COG0601 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel permeases SSO2619 suspect: %id E COG0747 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic components SSO2620 suspect: %id P COG0704 Inorganic ion transport and metabolism Phosphate uptake regulator SSO2622 suspect: LH R COG2050 General function prediction only Uncharacterized protein PaaI, possibly involved in aromatic compounds catabolism SSO2623 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO2624 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO2625 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2626 good S COG1545 Function unknown Uncharacterized ACR SSO2627 good H COG1541 Coenzyme metabolism Coenzyme F390 synthetase SSO2629 good R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO2631 suspect: LH S COG2210 Function unknown Uncharacterized ACR SSO2634 suspect: LH P COG0607 Inorganic ion transport and metabolism Rhodanese-related sulfurtransferases SSO2635 suspect: LH E COG0709 Amino acid transport and metabolism Selenophosphate synthase SSO2636 good R COG1319 General function prediction only FeS-containing oxidoreductases, xanthine dehydrogenase homologs SSO2637 good C COG2080 Energy production and conversion Predicted aldehyde dehydrogenases SSO2639 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO2642 good C COG1592 Energy production and conversion Rubrerythrin SSO2643 good C COG0247 Energy production and conversion Fe-S oxidoreductases SSO2646 good S COG0842 Function unknown Predicted integral membrane protein SSO2647 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO2651 good P COG2217 Inorganic ion transport and metabolism Cation transport ATPases SSO2652 suspect: LH K COG1522 Transcription Transcriptional regulators, Lrp family SSO2653 good R COG0671 General function prediction only Predicted phosphatases SSO2656 suspect: HSP C COG1290 Energy production and conversion Cytochrome b (b6-like) SSO2657 suspect: %id C COG0843 Energy production and conversion Cytochrome c oxidase, heme b and copper-binding subunit SSO2664 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO2665 good H COG1441 Coenzyme metabolism O-succinylbenzoate synthase and related enzymes SSO2668 good E COG0601 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel permeases SSO2669 good E COG0747 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic components SSO2670 check: MH E COG0444 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO2671 good E COG1173 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, permease components SSO2672 check: MH E COG1124 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO2673 good G COG1820 Carbohydrate transport and metabolism N-acetylglucosamine-6-phosphate deacetylase SSO2675 good E COG0308 Amino acid transport and metabolism Aminopeptidase N SSO2679 suspect: LH S COG2064 Function unknown Uncharacterized membrane proteins SSO2680 good N COG0630 Cell motility and secretion Predicted ATPases involved in pili biogenesis SSO2687 suspect: LH S COG1531 Function unknown Uncharacterized ArCR SSO2688 good K COG0640 Transcription Predicted transcriptional regulators SSO2689 good C COG1249 Energy production and conversion Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes SSO2691 good R COG0517 General function prediction only CBS domains SSO2693 good E COG1506 Amino acid transport and metabolism Dipeptidyl aminopeptidases/acylaminoacyl-peptidases SSO2694 normal O COG0501 Posttranslational modification, protein turnover, chaperones Predicted Zn-dependent proteases (possible chaperone function) SSO2697 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2701 suspect: LH G COG0477 Carbohydrate transport and metabolism Permeases SSO2704 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2706 good F COG0813 Nucleotide transport and metabolism Purine-nucleoside (and uridine) phosphorylase SSO2708 good O COG0309 Posttranslational modification, protein turnover, chaperones Hydrogenase formation factor SSO2710 suspect: %id R COG0457 General function prediction only TPR-repeat-containing proteins SSO2713 check: MH G COG1130 Carbohydrate transport and metabolism ABC-type sugar transport system, ATPase component SSO2714 normal G COG1175 Carbohydrate transport and metabolism ABC-type sugar transport systems, permease components SSO2716 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2717 good E COG1063 Amino acid transport and metabolism Threonine dehydrogenase and related Zn-dependent dehydrogenases SSO2718 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2719 good E COG0624 Amino acid transport and metabolism Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SSO2720 good E COG0160 Amino acid transport and metabolism PLP-dependent aminotransferases SSO2725 good R COG2129 General function prediction only Predicted phosphoesterases, related to the Icc protein SSO2726 suspect: LH E COG0531 Amino acid transport and metabolism Amino acid transporters SSO2727 good E COG0160 Amino acid transport and metabolism PLP-dependent aminotransferases SSO2728 suspect: Pn E COG0531 Amino acid transport and metabolism Amino acid transporters SSO2729 suspect: HSP R COG2129 General function prediction only Predicted phosphoesterases, related to the Icc protein SSO2730 good R COG1672 General function prediction only Predicted ATPases of the AAA superfamily SSO2732 good E COG0010 Amino acid transport and metabolism Arginase/agmatinase/formimionoglutamate hydrolase, arginase family SSO2733 good L COG1573 DNA replication, recombination and repair Uracil-DNA glycosylase SSO2737 good E COG0624 Amino acid transport and metabolism Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SSO2740 good R COG0517 General function prediction only CBS domains SSO2743 good S COG1602 Function unknown Uncharacterized ACR SSO2744 good S COG1533 Function unknown Uncharacterized ACR SSO2746 suspect: LH G COG0477 Carbohydrate transport and metabolism Permeases SSO2747 good G COG2017 Carbohydrate transport and metabolism Galactose mutarotase and related enzymes SSO2749 suspect: LH S COG1633 Function unknown Uncharacterized ACR SSO2750 suspect: LH L COG1197 DNA replication, recombination and repair Transcription-repair coupling factor - helicase of superfamily II SSO2755 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO2756 good C COG1013 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit SSO2757 good C COG0674 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit SSO2758 good C COG1014 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit SSO2759 normal C COG0437 Energy production and conversion Fe-S-cluster-containing hydrogenase components 1 SSO2760 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO2761 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO2762 good C COG2025 Energy production and conversion Electron transfer flavoprotein alpha-subunit SSO2763 good C COG2086 Energy production and conversion Electron transfer flavoprotein beta-subunit SSO2764 suspect: LH C COG1145 Energy production and conversion Ferredoxin 2 SSO2765 good O COG0492 Posttranslational modification, protein turnover, chaperones Thioredoxin reductase/alkyl hydroperoxide reductase SSO2766 suspect: Pn D COG1196 Cell division and chromosome partitioning Chromosome segregation ATPases SSO2769 suspect: %id S COG0668 Function unknown Uncharacterized ACR, integral membrane protein, YjeP/UPF0003 family SSO2770 good F COG0402 Nucleotide transport and metabolism Cytosine deaminase and related metal-dependent hydrolases SSO2773 good R COG0179 General function prediction only 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) SSO2774 good E COG0028 Amino acid transport and metabolism Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] SSO2775 suspect: %id M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO2776 good C COG0644 Energy production and conversion Dehydrogenases (flavoproteins) SSO2778 good T COG0589 Signal transduction mechanisms Universal stress protein UspA and related nucleotide-binding proteins SSO2779 good R COG0656 General function prediction only Aldo/keto reductases, related to diketogulonate reductase SSO2781 good R COG1708 General function prediction only Predicted nucleotidyltransferases SSO2782 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO2785 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO2786 good S COG0668 Function unknown Uncharacterized ACR, integral membrane protein, YjeP/UPF0003 family SSO2787 good S COG0586 Function unknown Uncharacterized membrane-associated protein, DedA family SSO2792 suspect: Pn C COG2221 Energy production and conversion Oxidoreductases related to nitrate reductase SSO2794 good C COG0437 Energy production and conversion Fe-S-cluster-containing hydrogenase components 1 SSO2795 suspect: HSP C COG0243 Energy production and conversion Anaerobic dehydrogenases, typically selenocysteine-containing SSO2796 good R COG0457 General function prediction only TPR-repeat-containing proteins SSO2800 check: MH C COG0604 Energy production and conversion NADPH:quinone reductase and related Zn-dependent oxidoreductases SSO2805 good C COG1290 Energy production and conversion Cytochrome b (b6-like) SSO2808 good I COG0318 Lipid metabolism Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SSO2811 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO2813 good R COG0454 General function prediction only Predicted acetyltransferases SSO2815 good C COG0674 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit SSO2816 good C COG1013 Energy production and conversion Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit SSO2817 good C COG2025 Energy production and conversion Electron transfer flavoprotein alpha-subunit SSO2819 good C COG0644 Energy production and conversion Dehydrogenases (flavoproteins) SSO2820 good G COG0574 Carbohydrate transport and metabolism Phosphoenolpyruvate synthase SSO2821 good C COG1526 Energy production and conversion Uncharacterized protein FdhD/NarQ required for formate dehydrogenase activity SSO2824 check: MH C COG1034 Energy production and conversion NADH dehydrogenase 75 kD subunit (chain G), NuoG/NQO3/Nad11 SSO2826 good R COG2041 General function prediction only Uncharacterized enzymes, related to nitrate reductase SSO2829 suspect: LH S COG0668 Function unknown Uncharacterized ACR, integral membrane protein, YjeP/UPF0003 family SSO2831 good O COG0464 Posttranslational modification, protein turnover, chaperones AAA+ class ATPases SSO2832 good R COG1402 General function prediction only Uncharacterized protein, putative amidase SSO2835 good E COG0683 Amino acid transport and metabolism Periplasmic leucine/isoleucine/valine-binding protein SSO2836 check: MH E COG0411 Amino acid transport and metabolism High-affinity branched amino acid transport system ATPase SSO2838 check: MH E COG0410 Amino acid transport and metabolism High-affinity branched amino acid transport system ATPase SSO2839 good E COG0559 Amino acid transport and metabolism Branched-chain amino acid ABC-type transport system, permease components SSO2841 good E COG0559 Amino acid transport and metabolism Branched-chain amino acid ABC-type transport system, permease components SSO2847 suspect: LH G COG1653 Carbohydrate transport and metabolism Sugar-binding periplasmic proteins/domains SSO2848 good G COG1175 Carbohydrate transport and metabolism ABC-type sugar transport systems, permease components SSO2849 good G COG0395 Carbohydrate transport and metabolism Sugar permeases SSO2850 check: MH G COG1130 Carbohydrate transport and metabolism ABC-type sugar transport system, ATPase component SSO2852 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2853 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO2861 suspect: LH R COG2050 General function prediction only Uncharacterized protein PaaI, possibly involved in aromatic compounds catabolism SSO2863 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO2864 good R COG1584 General function prediction only Predicted membrane protein SSO2868 suspect: %id R COG0697 General function prediction only Predicted permeases SSO2869 good C COG0281 Energy production and conversion Malic enzyme SSO2870 good R COG0454 General function prediction only Predicted acetyltransferases SSO2871 good I COG1250 Lipid metabolism 3-Hydroxyacyl-CoA dehydrogenase SSO2872 good S COG1545 Function unknown Uncharacterized ACR SSO2874 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO2875 good I COG0318 Lipid metabolism Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SSO2877 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO2878 check: MH R COG1065 General function prediction only Zn-dependent oxidoreductases SSO2879 suspect: %id S COG1975 Function unknown Uncharacterized BCR SSO2881 good C COG1032 Energy production and conversion Fe-S oxidoreductases family 2 SSO2884 suspect: LH S COG0599 Function unknown Uncharacterized ACR, homolog of gamma-carboxymuconolactone decarboxylase subunit SSO2885 good R COG0656 General function prediction only Aldo/keto reductases, related to diketogulonate reductase SSO2890 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO2892 good R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO2896 good P COG2217 Inorganic ion transport and metabolism Cation transport ATPases SSO2897 good K COG1733 Transcription Predicted transcriptional regulators SSO2899 good R COG2110 General function prediction only Predicted NA binding protein/domain related to histone macroH2A1 SSO2900 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO2901 good S COG2120 Function unknown Uncharacterized proteins, LmbE homologs SSO2905 good I COG1562 Lipid metabolism Phytoene/squalene synthetase SSO2907 good R COG1233 General function prediction only Phytoene dehydrogenase and related proteins SSO2908 good H COG0007 Coenzyme metabolism Uroporphyrinogen-III methylase SSO2909 good P COG0155 Inorganic ion transport and metabolism Sulfite reductase hemoprotein beta-component SSO2910 good P COG0155 Inorganic ion transport and metabolism Sulfite reductase hemoprotein beta-component SSO2911 good E COG0175 Amino acid transport and metabolism 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes SSO2912 good P COG2046 Inorganic ion transport and metabolism ATP sulfurylase SSO2914 suspect: LH R COG0730 General function prediction only Predicted permeases SSO2934 good E COG0146 Amino acid transport and metabolism N-methylhydaintoinase B SSO2935 good E COG0146 Amino acid transport and metabolism N-methylhydaintoinase B SSO2936 good E COG0145 Amino acid transport and metabolism N-methylhydaintoinase A SSO2938 good G COG0477 Carbohydrate transport and metabolism Permeases SSO2940 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO2941 good R COG0179 General function prediction only 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) SSO2942 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO2944 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO2950 suspect: LH L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO2954 good F COG0717 Nucleotide transport and metabolism Deoxycytidine deaminase SSO2960 good C COG1252 Energy production and conversion NADH dehydrogenase, FAD-containing subunit SSO2962 good E COG0028 Amino acid transport and metabolism Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] SSO2963 suspect: LH R COG0500 General function prediction only SAM-dependent methyltransferases SSO2965 suspect: Pn P COG0475 Inorganic ion transport and metabolism K efflux system, membrane domain SSO2969 good C COG1622 Energy production and conversion Cytochrome oxidase aa3/quinol oxidase, subunit II SSO2970 suspect: %id C COG1290 Energy production and conversion Cytochrome b (b6-like) SSO2973 good C COG0843 Energy production and conversion Cytochrome c oxidase, heme b and copper-binding subunit SSO2978 good J COG0182 Translation, ribosomal structure and biogenesis Translation initiation factor eIF-2B alpha subunit SSO2981 suspect: LH M COG0702 Cell envelope biogenesis, outer membrane Predicted nucleoside-diphosphate-sugar epimerases SSO2983 good M COG0438 Cell envelope biogenesis, outer membrane Glycosyltransferases I SSO2986 suspect: LH K COG1733 Transcription Predicted transcriptional regulators SSO2988 suspect: LH I COG1577 Lipid metabolism Mevalonate kinase SSO2995 suspect: %id P COG1914 Inorganic ion transport and metabolism Putative Mn transporter, NRAMP family SSO2996 good I COG1250 Lipid metabolism 3-Hydroxyacyl-CoA dehydrogenase SSO2998 normal H COG1441 Coenzyme metabolism O-succinylbenzoate synthase and related enzymes SSO3000 good O COG0459 Posttranslational modification, protein turnover, chaperones Chaperonin GroEL (HSP60 family) SSO3002 suspect: Pn M COG0463 Cell envelope biogenesis, outer membrane Glycosyltransferases involved in cell wall biogenesis SSO3003 good E COG1063 Amino acid transport and metabolism Threonine dehydrogenase and related Zn-dependent dehydrogenases SSO3004 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO3006 good G COG0383 Carbohydrate transport and metabolism Alpha-mannosidase SSO3008 suspect: %id R COG0673 General function prediction only Predicted dehydrogenases and related proteins SSO3009 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO3010 suspect: Pn G COG0477 Carbohydrate transport and metabolism Permeases SSO3011 good R COG0673 General function prediction only Predicted dehydrogenases and related proteins SSO3012 good R COG1132 General function prediction only ABC-type multidrug/protein/lipid transport system, ATPase component SSO3013 good R COG0673 General function prediction only Predicted dehydrogenases and related proteins SSO3014 good C COG0667 Energy production and conversion Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) SSO3015 good R COG0673 General function prediction only Predicted dehydrogenases and related proteins SSO3016 suspect: LH S COG2159 Function unknown Uncharacterized ACR, putative hydrolase SSO3022 good G COG1501 Carbohydrate transport and metabolism Alpha-glucosidases, family 31 of glycosyl hydrolases SSO3032 good G COG1472 Carbohydrate transport and metabolism Beta-glucosidase-related glycosidases SSO3035 good E COG0329 Amino acid transport and metabolism Dihydrodipicolinate synthetase/N-acetylneuraminate lyase SSO3042 check: MH R COG1065 General function prediction only Zn-dependent oxidoreductases SSO3043 suspect: %id E COG0747 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic components SSO3045 check: MH E COG1124 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO3046 check: MH E COG0444 Amino acid transport and metabolism ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSO3047 good E COG1173 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, permease components SSO3048 good E COG0601 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel permeases SSO3049 good R COG0673 General function prediction only Predicted dehydrogenases and related proteins SSO3051 good G COG1501 Carbohydrate transport and metabolism Alpha-glucosidases, family 31 of glycosyl hydrolases SSO3053 good E COG0747 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic components SSO3054 good C COG0667 Energy production and conversion Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) SSO3055 check: MH R COG1123 General function prediction only ATPase components of uncharacterized ABC-type transport system, contain duplicated ATPase domain SSO3058 good E COG0601 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel permeases SSO3059 good E COG1173 Amino acid transport and metabolism Dipeptide/oligopeptide/nickel ABC-type transport systems, permease components SSO3062 good F COG1957 Nucleotide transport and metabolism Inosine-uridine nucleoside N-ribohydrolase SSO3064 good I COG0318 Lipid metabolism Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SSO3066 suspect: LH G COG1653 Carbohydrate transport and metabolism Sugar-binding periplasmic proteins/domains SSO3067 good G COG1175 Carbohydrate transport and metabolism ABC-type sugar transport systems, permease components SSO3068 good G COG0395 Carbohydrate transport and metabolism Sugar permeases SSO3069 check: MH G COG1130 Carbohydrate transport and metabolism ABC-type sugar transport system, ATPase component SSO3071 good R COG1878 General function prediction only Uncharacterized ACR, predicted metal-dependent hydrolases SSO3072 good E COG0329 Amino acid transport and metabolism Dihydrodipicolinate synthetase/N-acetylneuraminate lyase SSO3074 suspect: %id R COG0697 General function prediction only Predicted permeases SSO3079 good G COG0477 Carbohydrate transport and metabolism Permeases SSO3083 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO3084 suspect: LH R COG2044 General function prediction only Predicted peroxiredoxins SSO3088 suspect: LH K COG0425 Transcription Predicted transcriptional regulators SSO3093 check: MH E COG0411 Amino acid transport and metabolism High-affinity branched amino acid transport system ATPase SSO3107 good E COG0129 Amino acid transport and metabolism Dihydroxyacid dehydratase/phosphogluconate dehydratase SSO3108 good N COG0805 Cell motility and secretion Sec-independent protein secretion pathway component TatC SSO3112 good S COG1545 Function unknown Uncharacterized ACR SSO3113 good I COG0183 Lipid metabolism Acetyl-CoA acetyltransferases SSO3114 good R COG1028 General function prediction only Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) SSO3115 good R COG0596 General function prediction only Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) SSO3117 good C COG1012 Energy production and conversion NAD-dependent aldehyde dehydrogenases SSO3118 good R COG0179 General function prediction only 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) SSO3120 good G COG0477 Carbohydrate transport and metabolism Permeases SSO3121 good G COG0477 Carbohydrate transport and metabolism Permeases SSO3124 good H COG1441 Coenzyme metabolism O-succinylbenzoate synthase and related enzymes SSO3125 good R COG1078 General function prediction only HD superfamily phosphohydrolases SSO3129 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO3130 good C COG1139 Energy production and conversion Uncharacterized conserved protein containing a ferredoxin-like domain SSO3131 good C COG0247 Energy production and conversion Fe-S oxidoreductases SSO3132 good R COG0491 General function prediction only Zn-dependent hydrolases, including glyoxylases SSO3136 good E COG2030 Amino acid transport and metabolism Monoamine oxidase SSO3143 good G COG0477 Carbohydrate transport and metabolism Permeases SSO3144 good C COG1804 Energy production and conversion Predicted acyl-CoA transferases/carnitine dehydratase SSO3145 good I COG1960 Lipid metabolism Acyl-CoA dehydrogenases SSO3147 suspect: %id G COG0477 Carbohydrate transport and metabolism Permeases SSO3148 good R COG0446 General function prediction only Uncharacterized NAD(FAD)-dependent dehydrogenases SSO3149 good G COG0477 Carbohydrate transport and metabolism Permeases SSO3153 suspect: LH L COG0675 DNA replication, recombination and repair Predicted transposases SSO3155 good R COG0655 General function prediction only Multimeric flavodoxin WrbA SSO3157 good H COG0095 Coenzyme metabolism Lipoate-protein ligase A SSO3158 good H COG0320 Coenzyme metabolism Lipoate synthase SSO3159 good H COG0095 Coenzyme metabolism Lipoate-protein ligase A SSO3161 good C COG0247 Energy production and conversion Fe-S oxidoreductases SSO3163 good C COG0277 Energy production and conversion FAD/FMN-containing dehydrogenases SSO3165 good C COG0277 Energy production and conversion FAD/FMN-containing dehydrogenases SSO3167 good F COG1051 Nucleotide transport and metabolism ADP-ribose pyrophosphatase SSO3169 check: MH R COG1131 General function prediction only ABC-type multidrug transport system, ATPase component SSO3170 good S COG1720 Function unknown Uncharacterized ACR, YaeB/UPF0066 family SSO3172 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO3174 good R COG0517 General function prediction only CBS domains SSO3176 good K COG1733 Transcription Predicted transcriptional regulators SSO3180 good G COG0477 Carbohydrate transport and metabolism Permeases SSO3182 suspect: %id T COG0515 Signal transduction mechanisms Serine/threonine protein kinases SSO3183 good T COG0589 Signal transduction mechanisms Universal stress protein UspA and related nucleotide-binding proteins SSO3184 suspect: %id E COG0531 Amino acid transport and metabolism Amino acid transporters SSO3187 good E COG0111 Amino acid transport and metabolism Phosphoglycerate dehydrogenase SSO3189 suspect: LH E COG0531 Amino acid transport and metabolism Amino acid transporters SSO3190 good C COG0243 Energy production and conversion Anaerobic dehydrogenases, typically selenocysteine-containing SSO3191 good C COG0243 Energy production and conversion Anaerobic dehydrogenases, typically selenocysteine-containing SSO3194 good C COG1012 Energy production and conversion NAD-dependent aldehyde dehydrogenases SSO3195 good G COG0524 Carbohydrate transport and metabolism Sugar kinases, ribokinase family SSO3197 good E COG0329 Amino acid transport and metabolism Dihydrodipicolinate synthetase/N-acetylneuraminate lyase SSO3198 good H COG1441 Coenzyme metabolism O-succinylbenzoate synthase and related enzymes SSO3200 good S COG1833 Function unknown Uncharacterized ACR SSO3201 good R COG2041 General function prediction only Uncharacterized enzymes, related to nitrate reductase SSO3202 good P COG0038 Inorganic ion transport and metabolism Permease, putative chloride channel SSO3203 check: MH I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO3204 good E COG1063 Amino acid transport and metabolism Threonine dehydrogenase and related Zn-dependent dehydrogenases SSO3205 good R COG0517 General function prediction only CBS domains SSO3206 good J COG0251 Translation, ribosomal structure and biogenesis Putative translation initiation inhibitor SSO3207 normal T COG0515 Signal transduction mechanisms Serine/threonine protein kinases SSO3209 good R COG0656 General function prediction only Aldo/keto reductases, related to diketogulonate reductase SSO3210 suspect: %id E COG0028 Amino acid transport and metabolism Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] SSO3211 good E COG0160 Amino acid transport and metabolism PLP-dependent aminotransferases SSO3214 good S COG1444 Function unknown Uncharacterized ACR SSO3216 good E COG0405 Amino acid transport and metabolism Gamma-glutamyltranspeptidase SSO3217 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO3219 check: MH M COG1209 Cell envelope biogenesis, outer membrane dTDP-glucose pyrophosphorylase SSO3224 suspect: %id E COG0531 Amino acid transport and metabolism Amino acid transporters SSO3226 good G COG1830 Carbohydrate transport and metabolism DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes SSO3228 suspect: LH R COG2244 General function prediction only Membrane protein involved in the export of O-antigen and teichoic acid, RfbX family SSO3230 good R COG0517 General function prediction only CBS domains SSO3231 good O COG0501 Posttranslational modification, protein turnover, chaperones Predicted Zn-dependent proteases (possible chaperone function) SSO3232 good F COG0519 Nucleotide transport and metabolism GMP synthase - PP-ATPase domain SSO3233 good H COG1492 Coenzyme metabolism Cobyric acid synthase CbiP/CobQ SSO3234 suspect: %id H COG0368 Coenzyme metabolism Cobalamin-5-phosphate synthase SSO3235 good H COG1270 Coenzyme metabolism Cobyrinic acid a,c-diamide synthase CobB/CbiA SSO3237 good E COG1063 Amino acid transport and metabolism Threonine dehydrogenase and related Zn-dependent dehydrogenases SSO3238 suspect: Pn O COG0501 Posttranslational modification, protein turnover, chaperones Predicted Zn-dependent proteases (possible chaperone function) SSO3239 good R COG1529 General function prediction only Oxidoreductases related to 4-hydroxybenzoyl-CoA reductase SSO3240 good J COG2016 Translation, ribosomal structure and biogenesis PUA domain (predicted RNA-binding domain) SSO3241 good M COG0463 Cell envelope biogenesis, outer membrane Glycosyltransferases involved in cell wall biogenesis SSO3245 good K COG1167 Transcription Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs SSO3250 suspect: LH S COG1814 Function unknown Uncharacterized membrane proteins SSO3251 good R COG2248 General function prediction only Predicted metal-dependent hydrolases SSO5140 good K COG1644 Transcription DNA-dependent RNA polymerase, subunit N (RpoN/RPB10) SSO5336 good J COG1552 Translation, ribosomal structure and biogenesis Ribosomal protein L40E SSO5345 good J COG2092 Translation, ribosomal structure and biogenesis Translation elongation factor EF-1beta SSO5357 suspect: Pn H COG1648 Coenzyme metabolism Precorrin-2 dehydrogenase SSO5410 good K COG1958 Transcription Small nuclear riboprotein (snRNP) homologs SSO5468 good K COG2012 Transcription DNA-directed RNA polymerase, subunit H, RpoH/RPB5 SSO5478 good J COG2075 Translation, ribosomal structure and biogenesis Ribosomal protein L24E SSO5479 good J COG2053 Translation, ribosomal structure and biogenesis Ribosomal protein S28E/S33 SSO5522 suspect: LH K COG1522 Transcription Transcriptional regulators, Lrp family SSO5542 good J COG1370 Translation, ribosomal structure and biogenesis Predicted RNA-binding proteins (contain PUA domain) SSO5544 good R COG1938 General function prediction only Archaeal enzymes of ATP-grasp superfamily SSO5561 good J COG1383 Translation, ribosomal structure and biogenesis Ribosomal protein S17E SSO5577 good K COG1761 Transcription DNA-directed RNA polymerase, subunit L (RPC19) SSO5672 suspect: Pn J COG2167 Translation, ribosomal structure and biogenesis Ribosomal protein L39E SSO5761 good J COG0130 Translation, ribosomal structure and biogenesis Pseudouridine synthase SSO5763 good J COG2163 Translation, ribosomal structure and biogenesis Ribosomal protein L14E SSO5782 suspect: Pn H COG0108 Coenzyme metabolism 3,4-dihydroxy-2-butanone 4-phosphate synthase SSO5798 good K COG2093 Transcription DNA-dependent RNA polymerase subunit E'' SSO5826 suspect: Pn S COG0864 Function unknown Uncharacterized ACR, YhhG family SSO5844 good J COG1998 Translation, ribosomal structure and biogenesis Ribosomal protein S27AE SSO5865 suspect: LH K COG1996 Transcription DNA-dependent RNA polymerase subunit RPC10 (contains C4-type Zn-finger) SSO5866 good J COG0023 Translation, ribosomal structure and biogenesis Translation initiation factor (SUI1) SSO6105 suspect: LH L COG1662 DNA replication, recombination and repair Insertion element IS1 protein InsB, putative transposase SSO6206 good S COG1888 Function unknown Uncharacterized ArCR SSO6223 good E COG0140 Amino acid transport and metabolism Phosphoribosyl-ATP pyrophosphohydrolase SSO6227 good E COG0139 Amino acid transport and metabolism Phosphoribosyl-AMP cyclohydrolase SSO6264 suspect: LH S COG1828 Function unknown Uncharacterized ACR, YexA/UPF0062 family SSO6374 good J COG2174 Translation, ribosomal structure and biogenesis Ribosomal protein L34E SSO6391 good J COG0199 Translation, ribosomal structure and biogenesis Ribosomal protein S14 SSO6401 good J COG0089 Translation, ribosomal structure and biogenesis Ribosomal protein L23 SSO6418 good J COG1997 Translation, ribosomal structure and biogenesis Ribosomal protein L37AE SSO6453 good J COG2126 Translation, ribosomal structure and biogenesis Ribosomal protein L37E SSO6454 good K COG1958 Transcription Small nuclear riboprotein (snRNP) homologs SSO6503 good S COG1698 Function unknown Uncharacterized ArCR SSO6550 suspect: LH L COG0675 DNA replication, recombination and repair Predicted transposases SSO6768 good K COG1919 Transcription DNA-directed RNA polymerase subunit K, RpoK/RPB6 SSO6855 good J COG0721 Translation, ribosomal structure and biogenesis Glu-tRNAGln amidotransferase C subunit SSO6877 suspect: Pn S COG1581 Function unknown Uncharacterized ArCR SSO7111 good J COG1631 Translation, ribosomal structure and biogenesis Ribosomal protein L44E SSO7114 good J COG2051 Translation, ribosomal structure and biogenesis Ribosomal protein S27E SSO7239 good K COG0425 Transcription Predicted transcriptional regulators SSO7348 suspect: Pn G COG0477 Carbohydrate transport and metabolism Permeases SSO7412 check: MH C COG1144 Energy production and conversion Ferredoxin-like subunits of formate hydrogenlyase SSO8090 suspect: LH S COG1343 Function unknown Uncharacterized ACR SSO8155 suspect: Pn R COG1078 General function prediction only HD superfamily phosphohydrolases SSO8284 suspect: LH S COG2250 Function unknown Uncharacterized ACR SSO8288 good L COG0675 DNA replication, recombination and repair Predicted transposases SSO8620 suspect: LH K COG2002 Transcription Regulators of stationary/sporulation gene expression SSO8813 suspect: LH T COG1848 Signal transduction mechanisms Archaeal proteins containing PIN domain SSO8814 suspect: LH K COG2002 Transcription Regulators of stationary/sporulation gene expression SSO8823 suspect: LH K COG2002 Transcription Regulators of stationary/sporulation gene expression SSO8861 good K COG0425 Transcription Predicted transcriptional regulators SSO8958 suspect: LH C COG1145 Energy production and conversion Ferredoxin 2 SSO9043 suspect: LH L COG1943 DNA replication, recombination and repair Predicted transposase SSO9136 suspect: LH S COG2250 Function unknown Uncharacterized ACR SSO9201 good I COG0365 Lipid metabolism Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases SSO9221 good K COG1594 Transcription DNA-directed RNA polymerase subunit M/Transcription elongation factor TFIIS SSO9378 suspect: LH K COG2002 Transcription Regulators of stationary/sporulation gene expression SSO9379 suspect: LH K COG2002 Transcription Regulators of stationary/sporulation gene expression SSO9485 good E COG0146 Amino acid transport and metabolism N-methylhydaintoinase B SSO9500 good K COG0425 Transcription Predicted transcriptional regulators SSO9509 good I COG1024 Lipid metabolism Enoyl-CoA hydratase/carnithine racemase SSO9518 good I COG0318 Lipid metabolism Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SSO9953 suspect: Pn K COG0640 Transcription Predicted transcriptional regulators SSO10051 suspect: LH R COG1534 General function prediction only Predicted RNA-binding protein containing KH domain SSO10784 good H COG1541 Coenzyme metabolism Coenzyme F390 synthetase SSO10788 suspect: Pn K COG0425 Transcription Predicted transcriptional regulators SSO10802 suspect: Pn C COG2080 Energy production and conversion Predicted aldehyde dehydrogenases SSO11071 check: MH C COG1144 Energy production and conversion Ferredoxin-like subunits of formate hydrogenlyase SSO11114 good C COG0437 Energy production and conversion Fe-S-cluster-containing hydrogenase components 1 SSO11231 good C COG1142 Energy production and conversion Fe-S-cluster-containing hydrogenase components 2 SSO11379 suspect: LH S COG1791 Function unknown Uncharacterized ACR, double-stranded beta-helix domain SSO11386 suspect: LH T COG1848 Signal transduction mechanisms Archaeal proteins containing PIN domain SSO11387 suspect: LH K COG2002 Transcription Regulators of stationary/sporulation gene expression SSO11412 suspect: LH P COG2217 Inorganic ion transport and metabolism Cation transport ATPases SSO11870 suspect: LH F COG1957 Nucleotide transport and metabolism Inosine-uridine nucleoside N-ribohydrolase SSO11873 suspect: LH F COG1957 Nucleotide transport and metabolism Inosine-uridine nucleoside N-ribohydrolase SSO11939 good K COG0425 Transcription Predicted transcriptional regulators SSO11972 suspect: LH N COG1826 Cell motility and secretion Component of Sec-independent protein secretion pathway TatA (homolog of Tha4/Hcf106) SSO12018 suspect: LH K COG2002 Transcription Regulators of stationary/sporulation gene expression SSO12093 suspect: Pn C COG0508 Energy production and conversion Dihydrolipoamide acyltransferases SSO12199 good S COG1694 Function unknown Uncharacterized ACR, MazG family SSO12256 good M COG1215 Cell envelope biogenesis, outer membrane Glycosyltransferases, probably involved in cell wall biogenesis
Last modified Friday January 27 13:08:00 2006