International Summer School

   From Genome to Life:

    Structural, Functional and Evolutionary approaches

 


GAUTHERET Daniel

AGC INSERM ERM206, Luminy case 906, 13 288 Marseille Cedex 09, France

title: RNA bioinformatics: identification of non coding RNA in genomic sequences

Following the recent discovery of hundreds of new regulatory RNAs in eukaryotic genomes, there has been a surging interest in computational tools for the identification of non coding transcripts. I will present the different methodologies available for this purpose, based on free energy calculation, probabilistic grammars, identification of known secondary structures, or phylogenetic comparisons. I will also introduce recent developments in the characterization of untranslated regions at the 5' and 3' end of genes.

ADDITIONAL DATA



HTTP LINK:

http://tagc.univ-mrs.fr/pub/erpin/