National Center for
Biotechnology NIH, Bldg 38A, Rm5N503, 8600
Rockville Pike, Bethesda, MD 20894, USA
title:
Evolutionary inferences from whole-genome
comparisons
I plan to
discuss the use of comparative genomics for the
construction of phylogenetic trees and detection of
massive horizontal gene transfer. I will show that
different methods developed for building
"genome-trees" contain a mixture of phylogenetic
and phenetic signals. Those enriched in
phylogenetic information may be highly sensitive
and allow us to delineate potential new major taxa.
I will also discuss the effect of selecting
different subsets of sites for phylogenetic
analysis on major aspects of tree topology.
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