Biology of Extremophiles

Jonathan Filée


Curiculum vitae


Born in Charleroi (Belgium) 20/12/1976

33 bis Villa de Chennevières

78700, Conflans-Sainte-Honorine

06 67 68 16 53



Education :

  • 1998 : Masters degree in Biochemistery, Université de Cergy-Pontoise (France).
  • Present : PhD degree, Université Paris-Sud Orsay (France), Institut de Génétique et Microbiologie, Laboratoire de Biologie moléculaire des Extrémophiles.
    PhD supervisor : Patrick Forterre.

    Subject : Phylogeny of viral protein involved in the replication and the metabolism of DNA.


Work experience :

  • 1999 : 7-months internship in the "Unité de Physiologie Microbienne" (Institut Pasteur, France) : Study of the 16S-23S ribosomal intergenic region of toxic Cyanobacteria by PCR-RFLP. DNA sequencing of this region and phylogeny. Primers designing to identify specifically toxic Cyanobacteria.
  • 2000 : 6-months internship in the "Laboratoire de Biologie Moléculaire du gène chez les Extrêmophiles" (IGM Orsay, France): Bioinformatic, sequence analysis of virus, molecular phylogeny and evolutionary consequences on the mecanisms of the DNA replication.


Skills :

  • Molecular Biology : PCR, Cloning, Sequencing, RFLP.
  • Computing : Phylogeny (Molphy, PAUP, Puzzle, Phylip...), Sequence analysis (BLAST, Clustal, COG, MUST), UNIX (Linux, C-programming language), DOS (Windows).


Presentations and abstracts :

  • 2000 : Origins, Diversity, and Evolution of Viruses. Fondation Des Treilles (France). Lecture : "Early or late virus ? A view on viral origin from DNA polymerase phylogenies." Jonathan Filée, Jacqueline Laurent & Patrick Forterre.
  • 2001 : School "Exobiology". CNRS. La Colle sur Loup (France).
  • 2002 : The Molecular Evolution Meeting. Sorrento (Italy). Poster : "What viral gene tel us about the evolution of the DNA world". Jonathan Filée, Patrick Forterre & Jacqueline Laurent
  • 2002: The Thirteen International Conference on Origin of Life. Oaxaca (Mexico). Poster : "Origin of DNA and DNA genome." Patrick Forterre, Hannu Myllykallio & Jonathan Filée.


Publications :


Thesis :