Our lab has been involved for some years in genome biology.
Several WEB-based tools where implemented on this server in order to respond
to specific needs in comparative genomics, genome annotation and deciphering
for people working on various projects locally as well as remotely.
We maintain a local sequence database of most complete microorganisms genomes, which can
be accessed individually or by selected groups ( all - bacteria - archaea - eucarya - thermophiles)
BLASTP cross-match is used to link genes from multiple genomes. Multiple genes environments and scatter plots from genome pairs are graphically displayed
1 (Altschul et al. , 1997, Nucleic Acids Res. 25:3389-3402)
2 (Tatusov, R.L., Koonin, E.V., and Lipman, D.J. (1997). Science 278: 631-637; Tatusov, et al. (2001). Nucleic Acids Res 29: 22-28.)
3 (F.Corpet, 1988, Nucl. Acids Res. 16 10881-10890.) 4 see InterPro Database and InterProScan at EMBL-EBI web site 5 Marchler-Bauer & al.. CDD: a Conserved Domain Database for protein classification. Nucleic Acids Res. 2005;33 Database Issue:D192-6.