I started working in the Molecular Biology of Extremophiles Laboratory, located in Orsay, near Paris, in September 1992 shortly after Pr. Patrick Forterre offered me the opportunity to lead a project aiming at the design and setup of the first cloning vector for hyperthermophilic Archeae, a set of fascinating microorganisms recently discovered in various extreme biototopes, beeing able to live at temperatures as high as 100*C. This was a long-term challenge, as the background was rather scarce in the lab, and I had to setup various facilities for the peculiar growth conditions of these hyperthermophilic and anaerobic microbes. My previous expertise was rather different from microbiology and hyperthermophily in general, as I spent 8 years in Dr. Ariel Prunell's laboratory (Institut Jacques Monod,Paris), working on DNA structure and conformation in the eucaryotic nucleosome. This led me to a good understanding of DNA topology and supercoiling problems, a field of long standing interest for Patrick. This common ground facilitated my adaptation to the "extreme" living conditions of the lab.
My CV can be found here.
You may also have a look on a poster displayed by myself and other members of the lab during the " First Internationnal Congress on Hyperthermophiles ", held in Estoril 2-6 June 96, Portugal.
Some additional informations will be available soon. Stay tuned.
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