Saccharomyces cerevisiae chromosome IV
>YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication 
MTIPHMKYAVSKTSENKVSNTVSPTQDKDAIRKQPDDIINNDEPSHKKIKVAQPDSLRETNTTDPLGHTKAALGEVASME
LKPTNDMDPLAVSAASVVSMSNDVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDLN
SLYIYYLIKLLGFEVKDQALIGTINSIVHINSQERVQDLGSAISVTNVEDPLAKKQTVRLIKDLQRAINKVLCTRLRLSN
FFTIDHFIQKLHTARKILVLTGAGVSTSLGIPDFRSSEGFYSKIKHLGLDDPQDVFNYNIFMHDPSVFYNIANMVLPPEK
IYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTCHWNLPGERIFNKIRNLELPLCPYCY
KKRREYFPEGYNNKVGVAASQGSMSERPPYILNSYGVLKPDITFFGEALPNKFHKSIREDILECDLLICIGTSLKVAPVS
EIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCGWTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPK
TL



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GenBank id: 6320163                 
Gene name:  SIR2                                                                                        
COG:        K COG0846 NAD-dependent protein deacetylases, SIR2 family                                   
Taxon:      4932 
Lineage:    Eukaryota:                                                                                  
            Opisthokonta:                                                                               
            Fungi:                                                                                      
            Dikarya:                                                                                    
            Ascomycota:                                                                                 
            saccharomyceta:                                                                             
            Saccharomycotina:                                                                           
            Saccharomycetes:                                                                            
            Saccharomycetales:                                                                          
            Saccharomycetaceae:                                                                         
            Saccharomyces:                                                                              
            Saccharomyces cerevisiae                                                                    

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